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ALKYL POLYGLYCOSIDE (APG)
Alkyl polyglycoside (APG) is a surfactant commonly used in the formulation of personal care and cosmetic products.
Alkyl polyglycoside (APG) is derived from natural raw materials, combining decyl alcohol and glucose to create a gentle and environmentally friendly detergent.
Known for Alkyl polyglycoside (APG)'s mildness and ability to produce stable foam, decyl glucoside is often found in skincare, haircare, and baby care products.

CAS: 68515-73-1
MF: C16H32O6
MW: 320.22
EINECS: 500-220-1

Synonyms
68515-73-1, Decyl glucoside, (3R,4S,5S,6R)-2-(Decyloxy)-6-(hydroxymethyl)tetrahydro-2H-Pyran-3,4,5-triol, Decyl D-glucopyranoside, Decyl D-glucoside, 54549-25-6, 141464-42-8, D-Glucopyranoside, decyl, (3R,4S,5S,6R)-2-decoxy-6-(hydroxymethyl)oxane-3,4,5-triol, (3R,4S,5S,6R)-2-(Decyloxy)-6-(hydroxymethyl)-tetrahydro-2H-Pyran-3,4,5-triol, 1-decyl-D-glucopyranoside, Capryl glycoside, MFCD23103077, Caprylyl glycoside, decyl glucopyranoside, EINECS 259-218-1, C16H32O6, n-decyl-d-glucopyranoside, D-Glucose decyl octyl ether, SCHEMBL43196, APG0814, DTXSID30893008, JDRSMPFHFNXQRB-IWQYDBTJSA-N, AKOS016004985, DS-3841, A867031, W-111093, W-203522, (3R,4S,5S,6R)-2-(DECYLOXY)-6-(HYDROXYMETHYL)OXANE-3,4,5-TRIOL,APG0810;D-Glucopyranose, oligomeric, decyl octyl glycosides;(C8-10)Alkyl ether of corn sugar;alkyl(c8,c10)polyglycoside;DECYL OCTYL D-GLUCOSE;D-glucose, decyl octyl ethers, oligomeric;Decyl-octyl glycosides oligomer;Octyldecyl Glucoside

Alkyl polyglycoside (APG) is a non-ionic surfactant that has gained popularity in the personal care and cosmetic industry for its mild and gentle cleansing properties.
Alkyl polyglycoside (APG) is synthesized by combining decyl alcohol derived from coconut or palm kernel oil with glucose obtained from cornstarch.
Alkyl polyglycoside (APG) is environmentally friendly nature, originating from renewable resources, aligns with the growing demand for sustainable and green formulations in the beauty and skincare market.

One of the notable features of Alkyl polyglycoside (APG) is its ability to provide effective yet mild cleansing without causing irritation.
Due to Alkyl polyglycoside (APG) gentle nature, it is commonly used in formulations for sensitive skin, baby products, and natural cosmetics.
Moreover, Alkyl polyglycoside (APG) is valued for its excellent foaming capabilities and stability, contributing to the creation of rich and creamy lathers in shampoos, body washes, and facial cleansers.

Beyond its cleansing properties, Alkyl polyglycoside (APG) is known for its compatibility with other ingredients, making it a versatile choice for various formulations.
Alkyl polyglycoside (APG) is often included in skincare products, such as cleansers and makeup removers, as well as haircare items like shampoos and conditioners.
As consumers increasingly seek products with plant-derived and gentle ingredients, Alkyl polyglycoside (APG) continues to play a key role in meeting these demands and contributing to the formulation of modern, eco-conscious personal care items.

Alkyl polyglycoside (APG) Chemical Properties
Density: 1.15 g/mL at 20 °C
Form: liquid
InChI: InChI=1/C16H32O6/c1-2-3-4-5-6-7-8-9-10-21-16-15(20)14(19)13(18)12(11-17)22-16/h12-20H,2-11H2,1H3/t12-,13-,14+,15-,16?/s3
InChIKey: JDRSMPFHFNXQRB-TVHDANIINA-N
EPA Substance Registry System: Alkyl polyglycoside (APG) (68515-73-1)

Uses
Alkyl polyglycoside (APG) is a nonionic surfactant used as a foamer, detergent, conditioner or emulsifier.
Alkyl polyglycoside (APG) can be used as a base surfactant or co-surfactant in detergents.
Alkyl polyglycoside (APG) has excellent foaming ability and good skin compatibility.
Alkyl polyglycoside (APG) can be combined with other glucosides using to enhance foaming and skin conditioning properties.
Alkyl polyglycoside (APG) can also be utilised in ionic formulations in order to increase foam depth and emulsification properties. Commonly used in shampoos and body washes.

Personal Care and Cosmetics:
Alkyl polyglycoside (APG) is extensively utilized in the personal care and cosmetic industry for its gentle cleansing properties.
Alkyl polyglycoside (APG) is a common ingredient in facial cleansers, body washes, and shampoos.
Alkyl polyglycoside (APG) is mild nature makes it suitable for products designed for sensitive skin and for baby care items.
Hair Care Products:
In the formulation of shampoos and conditioners, Alkyl polyglycoside (APG) serves as a surfactant that provides effective cleansing without causing irritation.
Alkyl polyglycoside (APG) contributes to the creation of rich lathers, leaving the hair clean and manageable.
Baby Products:
Due to its mildness and biodegradability, Alkyl polyglycoside (APG) is a preferred choice for baby care products, including shampoos, body washes, and wipes.
Alkyl polyglycoside (APG) is gentle cleansing action aligns well with the delicate nature of baby skin.
Natural and Organic Cosmetics:
As a plant-derived and environmentally friendly ingredient, Alkyl polyglycoside (APG) is often incorporated into natural and organic cosmetic formulations.
Alkyl polyglycoside (APG) meets the demand for green and sustainable ingredients in the beauty industry.
Dermatological Formulations:
Alkyl polyglycoside (APG) is used in dermatological products, including cleansers and creams prescribed by dermatologists.
Alkyl polyglycoside (APG) non-irritating properties make it suitable for individuals with sensitive or problematic skin.
Household and Industrial Cleaners:
Beyond personal care, Alkyl polyglycoside (APG) is found in household and industrial cleaning products.
Alkyl polyglycoside (APG) is surfactant properties make it effective in removing dirt and grease, and its biodegradability aligns with environmentally conscious cleaning solutions.
Agricultural Formulations:
In agriculture, Alkyl polyglycoside (APG) can be used in the formulation of certain pesticide and herbicide products.
Alkyl polyglycoside (APG) is biodegradability is advantageous in agricultural applications where environmental impact is a consideration.
Textile Industry:
The surfactant properties of Alkyl polyglycoside (APG) can be utilized in the textile industry for fabric softeners and laundry detergents.

Production Process
Raw Materials:
Decyl Alcohol: Derived from natural sources like coconut or palm kernel oil, decyl alcohol serves as the fatty alcohol precursor.
Glucose: Usually sourced from corn or other plant-based materials, glucose acts as the carbohydrate component.

Reaction (Glycosidation):
Decyl alcohol reacts with glucose in the presence of an acid catalyst or enzymes.
The reaction forms a glycoside bond, linking the decyl alcohol molecule with the glucose molecule.
ALKYL POLYGLYCOSIDES (APG)
Alkyl polyglycosides (APG) are a new environmental-friendly surfactants.
Alkyl polyglycosides (APG) surfactant is made from natural fatty alcohol and glucoside.
Alkyl polyglycosides (APG) have the following features: low surface tension, good solubility, strong detergency, strong alkaline resistance, good thickening effect, and good compatibility.


CAS Number: 68515-73-1, 110615-47-9
EC Number: 936-722-6
INCI name: C8-14 Alkyl Polyglycoside
Molecular Formula:CnH2nO6



141464-42-8 [RN], 54549-25-6 [RN], 68515-73-1 [RN], Decyl D-glucopyranoside, Decyl glucoside, D-Glucopyranoside, decyl, (3R,4S,5S,6R)-2-(DECYLOXY)-6-(HYDROXYMETHYL)OXANE-3,4,5-TRIOL, (3R,4S,5S,6R)-2-(Decyloxy)-6-(hydroxymethyl)tetrahydro-2H-Pyran-3,4,5-triol, (3R,4S,5S,6R)-2-(Decyloxy)-6-(hydroxymethyl)-tetrahydro-2H-Pyran-3,4,5-triol, (3R,4S,5S,6R)-2-decoxy-6-(hydroxymethyl)oxane-3,4,5-triol, [68515-73-1], 197236-02-5 [RN], 259-218-1 [EINECS], 41444-55-7 [RN], 500-220-1 [EINECS], 58846-77-8 [RN], 6801-91-8 [RN], Capryl glycoside, Caprylyl glycoside, decyl D-glucoside, D-Glucose decyl octyl ether, DS-3841, Glucoside, decyl, MFCD00063297 [MDL number], MFCD23103077 [MDL number], n-Decyl-?-D-Glucoside, n-Decyl-D-glucopyranoside, D-Glucopyranose, oligomeric, C10-16-alkyl glycosides, D-GLUCOPYRANOSE, OLIGOMERIC, C10-C16-ALKYLGLYCOSIDES, ALKYL D-GLUCOPYRANOSIDE, (C10-16)alkyl D-glycopyranoside, Glucopyranose, oligometric, C10-16-alkyl glycosides, D-Glucopyranoside, C10-16-alkyl, oligomeric



Alkyl polyglycosides (APG) are green, non-ionic surfactants produced from natural and renewable sources.
The majority of the Alkyl polyglycosides (APG) range can also be offered as RSPO Mass-Balance or palm-free, which are coconut-based.
As Alkyl polyglycosides (APG) are of natural origin and are mild and less irritating to skin; they are becoming more popular within personal care formulations.


Alkyl polyglycosides (APG) are also becoming popular replacements to other sulphate-based surfactants in sulphate-free marketed formulations.
Alkyl polyglycosides (APG) are a relatively new generation of commercially available environmentally friendly, mild, low-toxic, less-irritating and readily biodegradable surfactants.


Alkyl polyglycosides (APG) act as detergents, wetting agents, emulsifiers, solubilisers and foaming agents.
Alkyl polyglycosides (APG) are biosurfactants formed by the reaction of sugar and fat.
Biosurfactants derived from Alkyl polyglycosides (APG) are non-ionic surfactants, which are manufactured from renewable plant-based sources.


As Alkyl polyglycosides (APG) are environmentally friendly and formed by reacting fatty alcohol with sugar utilising acid as a catalyst, their demand for sustainable products is growing.
Alkyl polyglycosides (APG) are hemiacetal hydroxyl groups of glucose and fatty alcohol hydroxyl groups, which are obtained by losing one molecule of water under the catalysis of acid.


Alkyl polyglycosides (APG) is called a new generation of environmentally friendly green surfactant, the foreign nineties only to be industrialized.
Alkyl polyglycosides (APG) are a non-ionic surfactant, the use of raw materials from renewable natural resources from the glucose and fatty alcohol derivatives, the alkyl polyglycoside is completely biodegradable.


Alkyl polyglycosides (APG) are a nonionic high performance surfactant made from renewable raw materials.
Alkyl polyglycosides (APG) offer excellent detergency, high alkali stability, and superior eco-toxicity.
Alkyl polyglycosides (APG) are a mild, compatible and readily biodegradable high-performance surfactants


Alkyl polyglycosides (APG) have superior wetting & low surface tension
Alkyl polyglycosides (APG) are compatible with other types of surfactants
Alkyl polyglycosides (APG) are environmental and health compatibility also available in RSPO MB quality


Alkyl polyglycosides (APG) are high-quality nonionic surfactants that provide andenvironmentally friendly and completely biodegradable alternative to nonyl phenol ethoxylates (NPEs) and alcohol ethoxylates.
Specialy surfactants such as Alkyl polyglycosides (APG) and NPEs have been developed for the purpose of cleaning.


In the old days, the term “lye soap” applied to any fat treated with caustic soda (sodium hydroxide) to yield a water soluble fatty acid salt – the earliest surfactant.
Washing clothes and hands with a salt was effective from a cleaning standpoint, but not the best for tough grease stains and definitely not friendly to the skin.


Alkyl polyglycosides (APG) are derived from sugars, usually glucose derivatives, and fatty alcohols.
Alkyl polyglycosides (APG) are used to enhance the formation of foams in detergents for dishwashing and for delicate fabrics.
In addition to their favorable foaming properties, Alkyl polyglycosides (APG) are attractive because they readily biodegrade.


Alkyl polyglycosides (APG) is an non-ionic surfactant that can be used as a foaming, cleansing, conditioning, and thickening agent to liquid cleansers, shampoos and green cleaning.
Alkyl polyglycosides (APG) are derived from renewable raw materials such as coconut, corn starch and sugars, and is completely biodegradable.


Alkyl polyglycosides (APG) are produced by combining a sugar such as glucose with a fatty alcohol in the presence of acid catalysts at elevated temperatures.
Sugar-based surfactants represent a growing market.
Among these, Alkyl polyglycosides (APG) is on top.


Alkyl polyglycosides (APG) are GMO-free and contains no diethanolamine, lauryl sulfates, laureth sulfates, parabens and phthalates, or formaldehyde.
Alkyl polyglycosides (APG) are a new kind nonionic surfactant with comprehensive nature, which is directly compounded by renewable natural glucose and fatty alcohol.


Alkyl polyglycosides (APG) ahve characteristic of both common nonionic and anionic surfactant with high surface activity, good ecological security and intermiscibility.
Almost no surfactant can compare favorably with Alkyl polyglycosides (APG) in terms of ecological security, irritation and toxicity.


Alkyl polyglycosides (APG) are internationally recognized as the preferred "green" functional surfactant.
The incremental oil recovery by using Alkyl polyglycosides (APG) surfactant at 90 °C and the salinity of 30 g/L can reach 10.1%, which is nearly two times higher than that of common EOR surfactants.


Alkyl polyglycosides (APG) are called a new generation environmentally friendly surfactant.
Alkyl polyglycosides (APG) are a nonionic surfactant.
Because it is made from natural plant starch and fatty alcohol from coconuts, Alkyl polyglycosides (APG) are biodegradable.


Alkyl polyglycosides (APG) are called new generation envirementally friendly surfactants.
Alkyl polyglycosides (APG) have not been produced on the commercial scale until the nineties in the world.
Alkyl polyglycosides (APG) are classified as nonionic surfactants.


The feedstock of APG is based on fatty alcohol and glucose, which are obtained from renewable native resources.
Alkyl polyglycosides (APG), new environmental-friendly surfactants.
Alkyl polyglycosides (APG) surfactant is made from natural fatty alcohol and glucoside.


Alkyl polyglycosides (APG) have the following features: low surface tension, good solubility, strong detergency, strong alkaline resistance, good thickening effect, and good compatibility.
Alkyl polyglycosides (APG), commonly called APG for short, is a sugar-based eco-friendly green surfactant.


Alkyl polyglycosides (APG)'s safe, non-toxic, readily biodegradable, and skin-friendly.
Alkyl polyglycosides (APG) were first synthesized by German Chemist Emil Fischer in 1893.
Nowadays, Alkyl polyglycosides (APG) are produced by reacting fatty alcohols and glucose, which can all be obtained from renewable vegetal sources like corn, sugarcane, and coconut or palm.


Alkyl polyglycosides (APG) surfactants can improve the effect when compounding with other non-ionic or ionic surfactants.
Moreover, Alkyl polyglycosides (APG) significantly improve the mildness of the formulation.
Alkyl polyglycosides (APG) are non-toxic, non-irritating, well-compatible with the skin, and completely degradable.


Alkyl polyglycosides (APG) are a new type of nonionic surfactant obtained by losing a molecule of water from the hemiacetal hydroxyl group of glucose and the hydroxyl group of fatty alcohol under the catalysis of acid.
Alkyl polyglycosides (APG) have good compatibility. It can be compounded with various ionic and nonionic surfactants to produce a synergistic effect.


Alkyl polyglycosides (APG) have good foaming properties: rich and fine foam, good solubility, strong alkali, and electrolyte resistance.
Alkyl polyglycosides (APG) are non-toxic, non-irritating, and biodegradable.
The Alkyl polyglycosides (APG) have a good thickening capacity and compatibility with the skin.


In addition, Alkyl polyglycosides (APG) can significantly improve the mildness of the formula.
Sugar-based surfactants are not a new class of compounds.
As early as 1893, Fisher reported the preparation of methyl glycosides.


However, it was not until more than 40 years later that long-chain Alkyl polyglycosides (APG) were recognized to have surface activity.
Alkyl polyglycosides (APG) are a class of non-ionic surfactants widely used in a variety of cosmetic, household, and industrial applications.
Biodegradable and plant-derived from sugars, Alkyl polyglycosides (APG) are usually glucose derivatives, and fatty alcohols.


Alkyl polyglycosides (APG) are typically starch and fat, and the final products are typically complex mixtures of compounds with different sugars comprising the hydrophilic end and alkyl groups of variable length comprising the hydrophobic end.
When derived from glucose, they are known as Alkyl polyglycosides (APG).



USES and APPLICATIONS of ALKYL POLYGLYCOSIDES (APG):
Alkyl polyglycosides (APG) are widely used in personal care and household cleaners such as shampoo, body wash, all purpose cleaner, dishwashing liquid, laundry detergent and hand sanitizer
also available on palm oil-free (coconut oil base)


Alkyl polyglycosides (APG) are used Hard surface cleaning, Liquid dish detergent, Laundry detergent, Industrial cleaners, Highly alkaline detergents, All-purpose cleaners
Alkyl polyglycosides (APG) can be used in cosmetics, biochemical, food processing, plastic, petroleum, textile, printing and dyeing, papermaking, pharmaceutical, and others.


Alkyl polyglycosides (APG) are a class of non-ionic surfactants widely used in various cosmetic, household, and industrial applications.
Biodegradable and plant-derived from sugars, these surfactants are usually glucose derivatives and fatty alcohols.
The raw materials are typically starch and fat.


The final products are typically complex compounds with different sugars comprising the hydrophilic end and alkyl groups of variable length comprising the hydrophobic end.
When derived from glucose, they are known as Alkyl polyglycosides (APG).


Alkyl polyglycosides (APG) are used to enhance the formation of foams in detergents.
Alkyl polyglycosides (APG) are also used in the personal care industry because it is biodegradable and safe for sensitive skin.
Alkyl polyglycosides (APG) can be used in the cosmetic, biochemical, food processing, plastic and petroleum industries, textile, printing and dyeing, papermaking and pharmaceutical industries, and others.


Alkyl polyglycosides (APG) is with low iritation to skin,good compatibility,without negative effect,rich,delicate, stable and emulsifying bubble, so it is suitable for the application in the high-end personal care products:shampoo,cleanser, hand sanitizer and baby shampoo& shower gel.
Alkyl polyglycosides (APG) are with different carbon chain,when it is used in laundry liquid, it can reduce the friction between clothes, improve pine canopy of fabric, softness of fiber and cotton, which make cloth with a good feel.


When Alkyl polyglycosides (APG) are mixed with anionic surfactant in dishwashing detergent,the dishwashing detergent have better property of oil remove,good foam,especially the excellent compatibility of skin,there is not any harm to skin, moreover,its green and environmental.
Due to Alkyl polyglycosides (APG) are high alkaline resistance,it could be used in special detergent, furniture cleaning,cleaning industry as hard surface cleaning, textile industry as refining agent to resist high temperature.


Alkyl polyglycosides (APG) are a green surfactant,so it could be applied to bubble water and oil exploration as excellent foaming agent.
Alkyl polyglycosides (APG) can be widely used in Personal care and Household detergents such as shampoo, body wash, all-purpose cleaners, dishwashing liquid, laundry detergent and hand sanitizer.


Alkyl polyglycosides (APG) are with different carbon chain length,when used in laundry liquid,with fine foam.
Alkyl polyglycosides (APG) can reduce the friction between clothes,improve pine canopy of fabric,softness of fiber and cotton,which make cloth with a good feel.


In cosmetic, Alkyl polyglycosides (APG) are used to formulate Shampoo, Face wash, Hand wash, Shower gel and many more cleansing products for skin and hair.
Alkyl polyglycosides (APG) are derived from glucose derivatives and fatty alcohols.
Alkyl polyglycosides (APG) have minimal impact on the environment while efficiently maintaining the standard of cleaning and hygiene.


Since the properties, Alkyl polyglycosides (APG) become very important as high-performance components for cosmetic preparations due to their excellent environmental and skin compatibility.
Alkyl polyglycosides (APG) product showed low irritation to human skin and eyes.


When formulated with anionic surfactants, Alkyl polyglycosides (APG) products can reduce the irritation of the anionic surfactants.
Alkyl polyglycosides (APG) are biodegradable, environmentally friendly, and have a wide range of uses in several applications, including detergents, food emulsifiers, industrial emulsifiers, pharmaceutical granulating agents, and cosmetic surfactants, among others.


Alkyl polyglycosides (APG) are good with biological compatibility, it could be largely used in Personal Care and Home Care, like shampoo, cleansing cream, hand sanitizer, laundry detergent, body lotion,children bubble water, dish washing, kitchen cleaning agent, floor cleaning, toilet cleaner and so on. Alkyl polyglucoside also can be applied to glyphosate pesticide adjuvant, foaming agent for oil extract.


Alkyl polyglycosides (APG) belongs to low carbon alcohol, good solubility and compatibility,the most important point is that the low/no foam APG could dissolve other insoluble matter, so it could be largely applied to high alkali system as surfactants, like hard surface cleaning industry, textile auxiliary, high temperature and alkali refining agent, steel plate cleaning agent, beer bottle cleaning agent.


Alkyl polyglycosides (APG) are widely used in the following application areas: Personal care products and household detergents: shampoo, body-cleaner, creamrinses, hand sanitizer, dishwashing, etc.
Alkyl polyglycosides (APG) are a category of nonionic surfactant, it’s been widely used in a variety of daily chemicals, cosmetic, detergent and industrial applications.


The raw materials, Alkyl polyglycosides (APG), are mainly extracted from palm and coconut oil so it is considered eco-friendly because of their complete biodegradation, this property makes almost no other surfactant comparable to it.
So Alkyl polyglycosides (APG) have been widely used in variety of filed.


Liquid Hand Dish Detergents uses of Alkyl polyglycosides (APG): In products such as liquid hand dish detergent, where high foaming and good detergency are required, Alkyl polyglycosides (APG) provides excellent performance coupled with outstanding mildness to skin.
Alkyl polyglycosides (APG) are a green, non-toxic surfactant sourced from renewable plant-derived materials.


Known for Alkyl polyglycosides (APG) are exceptional detergency and wetting properties.
Due to rapid climate change, consumers are increasingly focusing on sustainable development and the usage of environmentally friendly and biodegradable items is rising, hence driving the use of Alkyl polyglycosides (APG) surfactants.


Alkyl polyglycosides (APG) are utilized in various industries, particularly in manufacturing household and personal care products.
Such surface active agents because of its non-toxic, non-stimulating and excellent surface activity and Alkyl polyglycosides (APG) are widely used in detergents, cosmetics, food and pharmaceutical sectors.


Thanks to its safeness, environmental friendliness, and excellent cleansing performance, Alkyl polyglycosides (APG) have been an emerging non-ionic surfactant increasingly used to produce skin-friendly and eco-friendly consumer products for use in Home & Personal care, such as dishwashing liquid, hand soaps liquid, facial cleansers, and shampoos.


Alkyl polyglycosides (APG) also feature great compatibility with a wide range of other surfactants.
Alkyl polyglycosides (APG) are also known as APG, Sparteine, or Triton.
This Alkyl polyglycosides (APG) surfactants can often be found in personal care products, laundry products, bathroom cleaners, and other cleaning products.


Alkyl polyglycosides (APG) is a green surfactant with excellent interfacial activity, emulsified ability, foaming performance, and wettability, which has great potential in enhancing heavy oil recovery at high-temperature and high-salinity conditions.
Alkyl polyglycosides (APG) had excellent interfacial activity and emulsification properties among all these surfactants.


Besides, Alkyl polyglycosides (APG) surfactant’s interfacial activity and emulsification properties almost did not decrease.
Alkyl polyglycosides (APG) even got better along with the increasing temperature or salinity, while those of other surfactants worsened significantly.
Alkyl polyglycosides (APG) are used to enhance the formation of foams in detergents.


Alkyl polyglycosides (APG) can be used in cosmetics, biochemicals, food processing, plastic, and petroleum industry, textile, printing and dyeing, papermaking, and pharmaceuticals.
Alkyl polyglycosides (APG) are also used in the personal care industry because it is biodegradable and safe for sensitive skin.


Thus, Alkyl polyglycosides (APG) are completely biodegradable.
Because of their non-toxicity, non-irritation and many excellent surface-active performances, the Alkyl polyglycosides (APG) are widely used in the fields of detergents, cosmetics, food and medicines.


So Alkyl polyglycosides (APG) are mostly used in the cosmetics industry.
Alkyl polyglycosides (APG) are widely used in hard surface detergents, dish washing detergents, industrial cleaning agent, glyphosate additives, fire additives.


Alkyl polyglycosides (APG) are both found in products intended for household cleaning, industrial and institutional detergents, metalworking, textile and leather processing, emulsion polymerisation, paints and coatings, oil and gas exporation and production, agriculture, and production of pulp and paper.


However, because of their excellent foaming, wetting, emulsifying and cleansing performance; you can find formulators using Alkyl polyglycosides (APG) within agrochemical, cleaning I&I, oil & gas and other industrial applications.
Alkyl polyglycosides (APG) are suitable for a multitude of applications.


-Laundry Detergents, Liquid Hand Dish Detergents, I&I Cleaners uses of Alkyl polyglycosides (APG):
Alkyl polyglycosides (APG) are well suited for laundry applications, where micellar solubilization, emulsification and detergency are required.
These Alkyl polyglycosides (APG) surfactants function as conventional non-ionic surfactants, but are easy to formulate because they do not exhibit a gel phase upon dilution.

Alkyl polyglycosides (APG) is soluble and stable in liquid formulations containing high levels of builders and electrolytes.
Also, these Alkyl polyglycosides (APG) surfactants are compatible, and in some cases synergistic, with enzymes, optical brightners, and other surfactants, including cationic.



BIOCHEMICAL USES OF ALKYL POLYGLYCOSIDES (APG):
Compared with non-ionic surfactants, Alkyl polyglycosides (APG) have the advantages of high critical micelle concentration, can be removed by dialysis, are not easily denatured, and have high ultraviolet light penetration performance.
Therefore, Alkyl polyglycosides (APG) play a role in the biochemical field of solubilization and reconstitution of membrane proteins.
The effect of Alkyl polyglycosides (APG) is good.
At the same time, Alkyl polyglycosides (APG) can also be used for the purification of cytochrome C, RNA polymerase, rhodopsin, fatty acids, etc., to stabilize these proteins.



FOOD PROCESSING INDUSTRY USES OF ALKYL POLYGLYCOSIDES (APG):
Food toxicology testing shows that Alkyl polyglycosides (APG) can be used as food emulsifiers, preservatives, foaming agents demulsifiers, etc.
Alkyl polyglycosides (APG) can disperse oil and water conjugates in food manufacturing, have foaming, anti-sugar, and fatty acid polymerization effects, and have the function of mixing food components uniformly and improving food taste.

Alkyl polyglycosides (APG) have the same or similar properties as glycerol fatty acid esters, sucrose fatty acid esters and sorbitol fatty acid esters and other surfactants, and have broad applications in food processing prospect.
Alkyl polyglycosides (APG) also have good hydrophilicity (HLB10-19).
As a food emulsifier, Alkyl polyglycosides (APG) solve the problem that Chinese food emulsifiers only have lipophilic (HLB5-9) products, and increase product varieties.



PLASTICS AND BUILDING MATERIALS USES OF ALKYL POLYGLYCOSIDES (APG):
Alkyl polyglycosides (APG) are used in plastic film in greenhouses, which can stabilize and flame retardant, and the anti-fogging effect is particularly good.
Alkyl polyglycosides (APG) are used as a new type of emulsifier for emulsion polymerization, and various products with excellent properties can be obtained.
In concrete, Alkyl polyglycosides (APG) are used as an air-entraining agent can meet the requirements of rich, stable and uniform foam.



DETERGANT USES OF ALKYL POLYGLYCOSIDES (APG):
Alkyl polyglycosides (APG) are non-toxic, have little skin irritation, are safe, and have significant thickening, thickening and decontamination power.
Using Alkyl polyglycosides (APG) to replace part of AES, LAS, 6501, AEO, Pingpingjia, K12, AOS to prepare meal lotion, bath lotion, shampoo, hard surface cleaner, facial cleanser, washing powder, etc., the effect is significant.

The detergent made of Alkyl polyglycosides (APG) has good solubility, mildness, and degreasing ability, has little skin irritation, is non-toxic, and is easy to rinse.
Adding Alkyl polyglycosides (APG) to washing powder, instead of AEO and LAS, can maintain the original washing performance, its mildness, hard water resistance and washing performance to cortical dirt are obviously improved, and it has both softness, antistatic and antistatic properties.

The shrinkage can also increase the solid content during the batching, and the flow performance is good, which not only can effectively save energy, but also can increase the output per unit time and reduce the cost.
In addition, Alkyl polyglycosides (APG) also have the characteristics of sterilization and disinfection, reducing irritation, and white and delicate foam.

Alkyl polyglycosides (APG) have stable performance in strong alkalis, strong acids and high-concentration electrolytes, have low corrosiveness, and are easily biodegradable.

Alkyl polyglycosides (APG) will not cause environmental pollution.
Therefore, Alkyl polyglycosides (APG) can be used to prepare industrial cleaning agents, such as metal cleaning, industrial bottle washing and transportation cleaning.

In traditional dishwashing, LAS/AEO or AES is the main ingredient, and more toxic co-solvents need to be added to improve the solubility and mildness, resulting in weak degreasing power.
The LAS/Alkyl polyglycosides (APG) mixture has excellent synergy.

The foam is better than a single component, has good hard water resistance, is gentle on the skin, feels comfortable after use, and is easy to rinse without leaving traces.
Alkyl polyglycosides (APG) can not only be used as a co-surfactant, but are also more suitable for use in dishwashing detergent as the main surface activity.

In the liquid detergent, Alkyl polyglycosides (APG) can be used to replace part of AES and LAS, which can be used to clean all kinds of fabrics.
Alkyl polyglycosides (APG) can effectively remove soil and greasy dirt.
At the same time, Alkyl polyglycosides (APG) have soft, antistatic and anti-shrinking functions.
Alkyl polyglycosides (APG) are still effective when used in hard water.

Alkyl polyglycosides (APG) is used alcohol polyoxyethylene ether (AEO-9) non-ionic surface active agent and other compound toilet cleaners, the decontamination effect is remarkable,
Alkyl polyglycosides (APG) is used meet the requirements of environmental labeling product technology for cleaning agents. APG is used as a toilet cleaner to effectively protect the rubber and plastic parts of the toilet.



PLASTICS AND BUILDING MATERIALS USES OF ALKYL POLYGLYCOSIDES (APG):
Alkyl polyglycosides (APG) are used in plastic film in greenhouses, which can stabilize and flame retardant, and the anti-fogging effect is particularly good.
Alkyl polyglycosides (APG) are used as a new type of emulsifier for emulsion polymerization, and various products with excellent properties can be obtained.
In concrete, Alkyl polyglycosides (APG) as an air-entraining agent can meet the requirements of rich, stable and uniform foam.



PESTICIDE USES OF ALKYL POLYGLYCOSIDES (APG):
Alkyl polyglycosides (APG) has good wetting and penetrating properties, is not sensitive to high concentrations of electrolytes, is biodegradable, does not pollute crops and land, and has excellent hygroscopicity.
What's more, Alkyl polyglycosides (APG) is different from polyoxyethylene type nonionic surfactants.

There is no reverse phase cloud point, Alkyl polyglycosides (APG) can effectively reduce the surface tension of the liquid medicine, delay the evaporation of the liquid water, and maintain the hydrated and dissolved state of the pesticide for a long time, which helps improve the absorption speed and absorption rate of the plant leaf to the pesticide.

Alkyl polyglycosides (APG) are suitable for pesticide emulsification Agents, wettable powders, insecticides, plant growth regulators, which can adjust soil temperature and have a significant synergistic effect on herbicides, insecticides and fungicides.
Alkyl polyglycosides (APG) can also be used to fix nitrogen in the soil.
Alkyl polyglycosides (APG) can also use C8~C22 APG as a preservative for the preservation of grains, fish and meat products and flowers.



OIL INDUSTRY USES OF ALKYL POLYGLYCOSIDES (APG):
Alkyl polyglycosides (APG) have state of shale pore fluid, so it can be used as an inhibitor.
Adding to the drilling fluid has good lubricity, strong inhibition, strong anti-pollution ability and good reservoir protection.

Alkyl polyglycosides (APG) can interact with other water-soluble polymers to achieve the best fluid loss reduction effect.
The temperature limit range of natural polymer drilling fluid can be broadened, and Alkyl polyglycosides (APG) are biodegradable, which is conducive to environmental protection.

In tertiary oil recovery, the use of C12~C16 Alkyl polyglycosides (APG) compound solution as the body replacement fluid has significantly enhanced the effect.
Compared with water flooding, Alkyl polyglycosides (APG) can improve the oil recovery.



TEXTILE AND PRINTING USES OF ALKYL POLYGLYCOSIDES (APG):
Alkyl polyglycosides (APG) can be used as an anti-wrinkle agent for cotton cloth in the textile industry, a powder dispersant for aqueous solutions, and an anti-dust agent.
Alkyl polyglycosides (APG) is suitable for processing such as refining and dyeing.

The solution does not easy to produce foam and can reduce stains.
Alkyl polyglycosides (APG) are especially suitable for high-temperature refining agents, high-temperature dyeing dispersants and leveling agents.
Alkyl polyglycosides (APG) are easily soluble in alkaline solution, and forms a uniform solution in an aqueous solution with a NaOH mass fraction of 10%.

In high-concentration NaOH and high-concentration sodium silicate solutions, Alkyl polyglycosides (APG) still maintain high surface activity.
Short carbon chain Alkyl polyglycosides (APG) are more soluble in alkalis and is suitable for the preparation of high-alkaline liquid cleaning agents.
For example, high-alkali scouring agent is formulated with 20% branched polyoxyethylene ether + 10% Alkyl polyglycosides (APG)+ 10% AES.

Good penetration and good decontamination performance.
In the textile printing and dyeing industry, if the silk fiber is refined to remove the viscose protein too much, the strength, luster and softness of the silk fiber will be damaged.

If Alkyl polyglycosides (APG) are added, over-refining can be prevented.
Take alkyl glycosides as the main component of the active agent, and appropriately add various additives to develop a green and environmentally friendly three-in-one high-efficiency refining agent without phosphorus and alkylphenol polyoxyethylene ethers, which can be used for high-efficiency and short-flow processes for pure cotton fabrics In the pre-treatment process.

Taking Alkyl polyglycosides (APG), odd carbon alcohol derivatives and environmentally friendly double oxidation stabilizers as the main raw materials, the new environmentally friendly three-in-one high-efficiency scouring agent is compounded with strong alkali resistance, no cloud point, less foam, no phosphorus, The characteristics of the structure of silicon and alkylphenol free, thereby reducing the sewage discharge of the pre-treatment process of printing and dyeing, can be widely used in short-process pre-treatment processes such as cotton, yarn knots and knitting, which is helpful for printing and dyeing enterprises and environmentally friendly and clean production.

The environmentally-friendly high-efficiency refining agent synthesized with Alkyl polyglycosides (APG) and fatty acid amide ether succinate monoester sulfonate as the main surfactant not only has good permeability, strong alkali resistance, low foam, but also is green and environmentally friendly.
Alkyl polyglycosides (APG) have good effects in a short process and can It has a positive impact on the whiteness and wool effect of textile products.

Alkyl polyglycosides (APG) itself have a good product viscosity.
Alkyl polyglycosides (APG) can also be used as a paraffin emulsifier instead of Pingping in the textile industry.



COSMETIC USES OF ALKYL POLYGLYCOSIDES (APG):
Alkyl polyglycosides (APG) can be stored for a long time in a large temperature range, and at the same time, it has the function of humidification, which fully meets the performance requirements of active ingredients for cosmetics.

Alkyl polyglycosides (APG) have been used as an active ingredient to make cosmetics at home and abroad.
Alkyl polyglycosides (APG) of cosmetics show good skin moisturizing and skin care properties.

A new generation of shampoos and baths made with Alkyl polyglycosides (APG) as a base has great foaming power, white and fine foam, softness to the skin, no irritation to the eyes, no pollution to the environment, good hard water resistance, and good conditioning and conditioning.
The maintenance function is especially suitable for the preparation of high-end toiletries.

In shampoos, because Alkyl polyglycosides (APG) are non-irritating to human skin and eyes, it can also reduce the irritation of other active agents compounded with it.
Therefore, Alkyl polyglycosides (APG) are one of the essential raw materials in low-irritation shampoos and children's shampoos.

Alkyl polyglycosides (APG) mildness has a protective effect on damaged hair.
Alkyl polyglycosides (APG) can be used as an active agent for hair dyeing and perming.
The styling performance after compounding with protein hydrolysate can be comparable to the commonly used styling agent-polyvinylpyrrolidone.

Alkyl polyglycosides (APG) are easier to rinse.
Alkyl polyglycosides (APG) can be used to formulate a new generation of shampoos and body washes, with strong foaming power and fine foam.

In skin cleansing products, Alkyl polyglycosides (APG) have good safety, mildness, decontamination, foaming and foam stability, compatibility and rheology.
Therefore, Alkyl polyglycosides (APG) are often used in products such as skin cleansing bath lotion and facial cleanser.
Adding a small amount of Alkyl polyglycosides (APG) as a conditioning agent to the bath lotion formula will make the skin feel more comfortable after washing.

In the conditioner, Alkyl polyglycosides (APG) have a softening effect on the skin, no irritation to the eyes, and a good conditioning and maintenance effect on the hair.
The synergy with quaternary ammonium salt is beneficial to improve the wet combability of the hair, while the dry combability is basically unchanged.
Adding some oils, such as octyldodecanol, to the conditioner will further improve the wet combability.

The use of Alkyl polyglycosides (APG) as an emulsifier in cosmetics can reduce the irritation of the formula, increase the moisturizing effect of the formula, and improve the efficacy of functional products.



PAPERMAKING AND FIREDIGHTING USES OF ALKYL POLYGLYCOSIDES (APG):
Alkyl polyglycosides (APG) can improve the gluing effect of paper, and when combined with other surfactants, it can produce excellent waste paper flotation deinking agent.
Alkyl polyglycosides (APG) are also widely used in fire fighting agents.



MEDICINE USES OF ALKYL POLYGLYCOSIDES (APG):
Alkyl polyglycosides (APG) have broad-spectrum antibacterial activity.
Alkyl polyglycosides (APG) have antibacterial activity against Gram-negative bacteria, positive bacteria and fungi, and the activity increases with the increase of the number of alkyl carbon atoms, so it can be used as a sanitary cleaning agent.

Alkyl polyglycosides (APG) are compatible with Chinese herbal medicines, and uses its excellent compatibility and non-irritating properties to prepare health care skin care products with antipruritic effects.
Alkyl polyglycosides (APG) derivatives have broad prospects in pharmaceuticals.



THE PERFORMANCE OF ALKYL POLYGLYCOSIDES (APG):
The performance of Alkyl polyglycosides (APG) applied in enhancing heavy oil recovery.
Alkyl polyglycosides (APG) are a green surfactant with good interfacial activity, emulsification, foaming and wettability, and has the potential to improve heavy oil recovery under high temperature and high salinity conditions.

The surface tension, interfacial tension, emulsion property, emulsion stability and emulsion droplet size of Alkyl polyglycosides (APG) were studied.
Also the effects of temperature and salinity on the interfacial activity and emulsifying properties of Alkyl polyglycosides (APG) were studied.
The results show that Alkyl polyglycosides (APG) have good interfacial activity and emulsifying properties among all surfactants.

In addition, the interfacial activity and emulsifying performance of Alkyl polyglycosides (APG) are stable, and even became better with the increase of temperature or salinity, while the interfacial activity and emulsifying performance of other surfactants got worse to varying degrees.

For example, at 90℃ with a salinity of 30 g/L, the oil recovery by using Alkyl polyglycosides (APG) can reach up to 10.1%, nearly twice times higher than that ordinary EOR surfactant.
The results show that Alkyl polyglycosides (APG) are an effective surfactant for improving heavy oil recovery at high temperature and high salinity condition.



THE PROPERTIES OF ALKYL POLYGLYCOSIDES (APG):
The functional attributes of Alkyl polyglycosides (APG) surfactant,such as foaming,emulsification and bio-degradability.
*Foaming:
Alkyl polyglycosides (APG) surfactants are non-toxic, non-irritating, well compatible and have good foaming and surface activity.
Alkyl polyglycosides (APG) are widely used in detergents and personal care products to promote foam formation.



ALKYL POLYGLYCOSIDES (APG) MARKET OVERVIEW:
Alkyl polyglycosides (APG) Market size is forecast to reach around $911.10 million by 2026, after growing at a CAGR of 5.2% during 2021-2026.
Alkyl polyglycosides (APG) are a range of non-ionic surfactants derived from renewable raw materials like vegetable oils and starch and is used as active ingredients in personal care products, cosmetic, household, and industrial applications.

Alkyl polyglycosides (APG) are also called as a green surfactant owing to its less toxic nature than synthetic surfactants.
Alkyl polyglycosides (APG) offer excellent interfacial activity, emulsified ability, and foaming performance properties, which further drive the growth of
Alkyl polyglycosides (APG) Market. Furthermore, the high demand for environment-friendly Alkyl polyglycosides (APG) usage from end-use industries is expected to drive market growth.
However, growing demand for cosmetic and personal care products coupled with growing population, and improving living standards further propels the growth of the Alkyl polyglycosides (APG) Market.



FEATURES OF ALKYL POLYGLYCOSIDES (APG):
Alkyl polyglycosides (APG) are nonionic surfactants made from natural fatty alcohol and glucose whichare derived from plant resources.
Alkyl polyglycosides (APG) are mild to human skin and eyes, readily biodegradable.

Introductions and Properties:
1.Nonionic surfactant made from natural fatty alcohols and glucose derivedfromrenewable plants.
2.Superior detergency , wetting and surface active ability.
3.High solbility in concentrated alkaline solutions and other electrolytes andwill
solubilize other less soluble ingredients.
4.Good compatibility with all other types of surfactants and synergistic effects canbe found.
It can improve the mildness of formulations significantly.
5.Produces rich and stable foam.
6.Non-toxic, non-irritating to skin, readily biodegradable.



ALKYL POLYGLYCOSIDES (APG), APPLICATION IN INDUSTRY?
The use cases for Alkyl polyglycosides (APG) are innumerable, with an estimated global market worth $1.1B and projected to increase over 8% during 2021 – 2031.

Alkyl polyglycosides (APG) are typically used to enhance the formation of foams in detergents (surface cleaners, dishwashing and laundry detergents), but because it’s biodegradable and safe for sensitive skin, it has also found multiple applications in the personal care sector, including:
*Bath Products
*Cleansers & Wipes
*Oral Care
*Cosmetics

But its uses extend beyond these;
Alkyl polyglycosides (APG) can be used in fire equipment as a foaming agent, in the paper industry, it improves the softness of paper.
As a fabric softener and dyeing auxiliaries in the textile industry,
Alkyl polyglycosides (APG) can even be used as a gel, lubricant and wetting agent.



PROPERTIES OF ALKYL POLYGLYCOSIDES (APG):
Alkyl polyglycosides (APG) are a nonionic surfactant made by one step technology, its raw material is renewable plant: natural fatty alcohol and glucose.

Alkyl polyglycosides (APG) are with low surface tension, good solubility,strong detergency, and high concentration of electrolyte, strong alkali resistance, good thickening effect,good compatibility, it can improve the effect when compound with other nonionic or ionic surfactants, moreover,it can improve performance significantly. When use it, products could with good and abundant foam, stable,exquisite,nontoxic, seldom stimulating, good compatible with skin, readily biodegradable.

Alkyl polyglycosides (APG) stored with long time in room temperature, there will be a samll amount of solid precipitation or appearance of turbidity, it caused by magnesium, but this turbidity has no negative effect, as adjust the pH value to below 9, the cloudy would be disappeared.



BENEFIT FROM VERSATILE UTILITY OF ALKYL POLYGLYCOSIDES (APG):
Alkyl polyglycosides (APG) cater to different needs across the board.
Alkyl polyglycosides (APG) are an invaluable ingredient in personal care products such as shampoos and body cleansers, household cleaning agents, plus hard-surface cleaning solutions.
Whether it's lathering up your hair or tackling stubborn grime, Alkyl polyglycosides (APG) is your ally.



FEATURES AND BENEFITS OF ALKYL POLYGLYCOSIDES (APG):
*Mild performance, non-irritating to eyes, good ecological compatibility.
*Rich, fine and stable foaming power and strong decontamination power.
*Stable to acid, alkali and salt media, with good compatibility with anionic, cationic, non-amphoteric surfactants.
*Rapid and complete biodegradation with bactericidal properties.



YOUR GREEN TICKET TO SUPERIOR PERFORMANCE OF ALKYL POLYGLYCOSIDES (APG):
*Created from nature's renewable sources, a testament to its green credentials.
*Supplies extraordinary detergency and wetting properties for high-performance results.
*Imparts excellent solubility even in concentrated alkaline mediums and diverse electrolytes.
*Proves compatibility with all kinds of surfactants, guaranteeing adaptability.
*Generates abundant, prolonged foam to ensure optimal user experience.
*Safe to use being non-toxic, non-irritating, and fully biodegradable.



SPECIAL FEATURES INCLUDE OF ALKYL POLYGLYCOSIDES (APG):
*Organic and renewable: Made up of fatty alcohols and glucose derived from plants.
*Outstanding cleaning capability: Known for outstanding detergency and wetting properties.
*Wide compatibility: Works synergistically with other surfactants enhancing formulation mildness.
*Eco-friendly: Biodegradable, non-toxic, and non-irritative nature of APG enhances its environmental friendliness.



PROPERTIES OF ALKYL POLYGLYCOSIDES (APG):
Alkyl polyglycosides (APG) are called a new generation environmentally friendly surfactant.
Alkyl polyglycosides (APG) are a nonionic surfactant. Because it is made from natural raw materials, APG is very mild and readily biodegradable.
Alkyl polyglycosides (APG) have excellent mildness, foaming performance, and the ability to reduce irritation.
In addition, Alkyl polyglycosides (APG) exhibit excellent caustic stability and solubility in highly concentrated salt, alkali, and surfactant solutions.



PREPARATION OF ALKYL POLYGLYCOSIDES (APG):
Alkyl polyglycosides (APG) are produced by combining a sugar such as glucose with a fatty alcohol in the presence of acid catalysts at elevated temperatures
Alkyl polyglycosides (APG) are characterised by a saccharide unit and a hydrophobic alkyl chain.



ALKYL POLYGLYCOSIDES (APG) MARKET SIZE AND SHARE ANALYSIS - GROWTH TRENDS AND FORECASTS (2023-2028)
Alkyl polyglycosides (APG) Surfactants Market is segmented by product (fatty alcohol, sugar, cornstarch, vegetable oil, and other products), application (personal care and cosmetics, home care products, industrial cleaners, agricultural chemicals, and other applications), and Geography (Asia-Pacific, North America, Europe, South America, and Middle-East and Africa).



DERIVATIVES OF ALKYL POLYGLYCOSIDES (APG):
Nowadays, Alkyl polyglycosides (APG) are available in sufficient quantities and at competitive costs so that their use as a raw material for the development of new speciality surfactants based on Alkyl polyglycosides (APG) is arousing considerable interest.
Thus, the surfactants properties of Alkyl polyglycosides (APG), for example foam and wetting, could be modified as required by chemical transformation.

Derivation of Alkyl polyglycosides (APG) is a widely engaged work at present.
There are many kinds of Alkyl polyglycosides (APG) derivatives by means of nucleophilic substitution.
In addition to reacting with esters or ethoxides, ionic Alkyl polyglycosides (APG) derivatives, such as sulfates and phosphates, can also be synthesized.

Starting from Alkyl polyglycosides (APG) having alkyl chains(R) of 8,10,12,14 and 16 carbon atoms(C8 to C16)and an average degree of polymerization(DP) of 1.1 to 1.5, three series of Alkyl polyglycosides (APG) derivatives were prepared.
In order to investigate the change in the surfactant properties hydrophilic or hydrophobic substituents were introduced leading to Alkyl polyglycosides (APG) glycerol ethers.

In view of their numerous hydroxyl groups, Alkyl polyglycosides (APG) are over-functionalized molecules by far the most.
Alkyl polyglycosides (APG) derivatizations are carried out by chemical transformation of the free primary hydroxyl group at the C6 atom.
Although primary hydroxyl groups are more reactive than secondary hydroxyl groups, this difference is not sufficient in most cases to achieve a selective reaction without protective groups.

Accordingly, derivatization of an Alkyl polyglycosides (APG) can always be expected to produce a product mixture of which the characterization involves considerable analytical effort.
A combination of gas chromatography and mass spectrometry was shown to be the preferred analysis method.

In the synthesis of Alkyl polyglycosides (APG) derivatives, it has proved effective to use an Alkyl polyglycosides (APG) with a low DP value of 1.1, in the following referred to as alkyl aminoglycosides.
This leads to less complex product mixtures and as a consequence to less complicated analyses.



PHYSICAL and CHEMICAL PROPERTIES of ALKYL POLYGLYCOSIDES (APG):
CAS Number: 68515-73-1, 110615-47-9
EC Number: 936-722-6
Molecular Formula:CnH2nO6
Molecular Weight:320-370
CAS No.: 68515-73-1
Chemical Name: APGCH-0810
Molecular Formula/MF: C16H32O6
EINECS No.: 500-220-1
HS Code 3402420000
Classification: Organic Intermediate
Grade Standard: Cosmetic Grade
Purity: 50%,60%,62%,70%
Appearance: Colorless/Light yellow liquid

Appearance, 25ºC: Light yellow liquid
Solid Content: %50.0-52.0
Water (wt %): 48.0-50.0
PH Value (20% aq.): 11.5-12.5
Viscosity (20ºC, mPa.s): 2000-4000
Free Fatty Alcohol (wt %): 1 max
Sulfated Ash (wt %): 3 max
Appearance: Colorless, light yellow transparent liquid
Alkyl Carbon number: 8-10
Active Matter(Wt%): 50-52
PH value: 11.5-12.5
HLB value: 15-16
Residual alcohol: ≤1%
Glucose polymerization degree: 1.6-1.8



FIRST AID MEASURES of ALKYL POLYGLYCOSIDES (APG):
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person. Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ALKYL POLYGLYCOSIDES (APG):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of ALKYL POLYGLYCOSIDES (APG):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of ALKYL POLYGLYCOSIDES (APG):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ALKYL POLYGLYCOSIDES (APG):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of ALKYL POLYGLYCOSIDES (APG):
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


ALKYL SILANE EMULSION
Alkyl silane emulsion is a type of emulsion that contains alkyl silane molecules dispersed in water.
Alkyl silanes are organic compounds that contain a silane (SiH4) group attached to a hydrocarbon chain.
Alkyl silane emulsion is commonly used as adhesion promoters, water repellents, and surface modifiers in various industries.



APPLICATIONS


Alkyl silane emulsions have a wide range of applications in various industries.
Some of the common applications of alkyl silane emulsions include:


Surface modification:
Alkyl silane emulsions are commonly used to modify the surface properties of various substrates, such as glass, metal, concrete, and ceramics.
The alkyl silane molecules in the emulsion can react with the surface to form a thin layer that modifies the surface properties, such as improving adhesion, water repellency, and chemical resistance.


Coatings:
Alkyl silane emulsions are used to produce coatings for various substrates, including glass, metal, and concrete.
Alkyl silane emulsion can provide excellent adhesion, durability, and water repellency, making them ideal for use in harsh environments.


Adhesives and sealants:
Alkyl silane emulsions can be used as adhesion promoters in the production of adhesives and sealants.
Alkyl silane emulsion can improve the bonding strength and adhesion properties of the adhesive or sealant, making it more reliable and durable.


Composites:
Alkyl silane emulsions can be used to produce composites, where they can act as a coupling agent between the substrate and the matrix material.
This can improve the interfacial bonding between the substrate and the matrix, resulting in improved mechanical properties of the composite.


Textile treatment:
Alkyl silane emulsions can be used to treat textiles to improve their water repellency, stain resistance, and durability.
This makes them suitable for use in outdoor clothing, sportswear, and other applications where water resistance is important.

Overall, alkyl silane emulsions have a wide range of applications, and their use is expected to continue to grow as new formulations are developed and new applications are discovered.


Applications for alkyl silane emulsion:

Water repellent coatings for building materials, such as concrete, brick, and stone
Corrosion protection for metal surfaces in marine, automotive, and industrial applications
Adhesion promoter for paints, coatings, and adhesives
Hydrophobic treatment for textiles, paper, and leather
Dust and dirt repellent coatings for glass surfaces, such as windows and mirrors
Antistatic coatings for electronic devices and packaging materials
Release agent for molds and casting processes
Surface modification for nanoparticles and other fine particles
Enhancer for silicone rubbers, elastomers, and resins
Coating for automotive windshields to improve visibility in rain and snow
Waterproofing for outdoor fabrics, such as tents and awnings
Water and oil repellent coatings for food packaging, such as paper cups and containers
Surface treatment for ceramics and glassware to improve scratch resistance and durability
Antimicrobial coatings for medical devices and equipment
Protective coating for solar panels to improve efficiency and durability
Surface modification for carbon fibers to improve adhesion in composites
Hydrophobic coating for lenses and optical surfaces
Antifouling coating for ship hulls to prevent the growth of marine organisms
Coating for photovoltaic cells to improve durability and weather resistance
Adhesion promoter for glass fiber reinforced plastics (GRP)
Protective coating for metal substrates in the aerospace industry
Water and stain repellent coatings for carpets and upholstery
Surface modification for nanoparticles used in drug delivery systems
Adhesion promoter for pressure sensitive adhesives (PSAs)
Water repellent coatings for concrete roof tiles and slates
Hydrophobic coating for membranes used in fuel cells
Coating for electronic components to improve moisture resistance and reliability
Waterproofing for swimming pool tiles and grout
Adhesion promoter for sealants and caulks
Surface treatment for filler materials used in paints and coatings.


Alkyl silane emulsions are widely used as surface modifiers to improve the surface properties of various substrates.
Alkyl silane emulsions are commonly used in the production of coatings, adhesives, sealants, and composites.
Alkyl silane emulsions are used in the glass industry to produce water-repellent coatings for windows and windshields.

Alkyl silane emulsions are used in the automotive industry to improve the adhesion of paint coatings to metal surfaces.
Alkyl silane emulsions are used to improve the water resistance and durability of concrete and masonry surfaces.

Alkyl silane emulsions are used in the production of waterproofing membranes and roofing materials.
Alkyl silane emulsions are used in the textile industry to produce water-repellent and stain-resistant fabrics.

Alkyl silane emulsions are used to improve the adhesion of coatings to plastic and rubber surfaces.
Alkyl silane emulsions are used in the production of printing inks and toners.

Alkyl silane emulsions are used to improve the adhesion of tapes and labels to various surfaces.
Alkyl silane emulsions are used to modify the surface properties of electronic components and devices.

Alkyl silane emulsions are used to improve the adhesion of coatings to optical fibers and lenses.
Alkyl silane emulsions are used to produce hydrophobic coatings for medical implants and devices.
Alkyl silane emulsions are used to improve the water resistance and durability of wood and wood-based materials.

Alkyl silane emulsions are used in the production of high-performance paints and coatings.
Alkyl silane emulsions are used to improve the bonding strength of adhesives and sealants to various substrates.

Alkyl silane emulsions are used to produce anti-corrosion coatings for metal surfaces.
Alkyl silane emulsions are used in the production of composites for aerospace and automotive applications.
Alkyl silane emulsions are used to modify the surface properties of ceramics and glass-ceramics.

Alkyl silane emulsions are used to improve the water resistance and durability of paper and paper-based materials.
Alkyl silane emulsions are used in the production of self-cleaning surfaces and coatings.

Alkyl silane emulsions are used to improve the adhesion of coatings to concrete and asphalt surfaces.
Alkyl silane emulsions are used to produce water-repellent coatings for marine applications.

Alkyl silane emulsions are used to improve the water resistance and durability of outdoor furniture and equipment.
Alkyl silane emulsions are used to modify the surface properties of nanoparticles and nanomaterials.

Alkyl silane emulsions are used in the production of anti-fouling coatings for marine applications.
Alkyl silane emulsions are used to produce coatings for food packaging materials.
Alkyl silane emulsions are used to improve the adhesion of coatings to powder-coated surfaces.

Alkyl silane emulsions are used in the production of water-repellent coatings for solar panels.
Alkyl silane emulsions are used to improve the water resistance and durability of sports equipment and accessories.

Alkyl silane emulsion is widely used in the construction industry to improve the water resistance and durability of building materials.
Alkyl silane emulsion is used to produce waterproofing membranes, sealants, and coatings for roofs, walls, and floors.

Alkyl silane emulsion is used in the food industry to produce water-repellent coatings for packaging materials to improve their shelf life.
Alkyl silane emulsion can also be used to produce anti-fog coatings for food packaging.

Alkyl silane emulsion is used in the production of ceramics to improve their surface properties.
Alkyl silane emulsion can be used to improve the adhesion of glazes to ceramic surfaces, as well as to modify their electrical and thermal properties.

Alkyl silane emulsion is used in the production of nanomaterials to modify their surface properties and improve their stability.
Alkyl silane emulsion can be used to produce nanoparticles with controlled size and shape, and to enhance their dispersion in solvents and polymers.

Alkyl silane emulsion is used in the production of electronic devices to modify their surface properties and improve their performance.
Alkyl silane emulsion can be used to improve the adhesion of conductive coatings to electronic components, as well as to modify their optical and electrical properties.
Alkyl silane emulsion is used in the production of textiles to produce water-repellent and stain-resistant fabrics.

Alkyl silane emulsion can also be used to produce anti-static and anti-microbial fabrics.
Alkyl silane emulsion is used in the production of cosmetics to improve their water resistance and durability.

Alkyl silane emulsion can be used to produce water-repellent and long-lasting lipsticks, eyeliners, and mascaras.
Alkyl silane emulsion is used in the production of paints and coatings to improve their adhesion and durability.

Alkyl silane emulsion can be used to produce high-performance coatings for automotive, marine, and aerospace applications.
Alkyl silane emulsion is used in the production of paper to improve its water resistance and durability.
Alkyl silane emulsion can be used to produce water-repellent and anti-static paper, as well as to improve its printing properties.

Alkyl silane emulsion is used in the production of adhesives and sealants to improve their bonding strength and durability.
Alkyl silane emulsion can be used to produce structural adhesives for bonding metal, plastic, and composite materials.

Alkyl silane emulsion is used in the production of inks and toners to improve their adhesion and durability.
Alkyl silane emulsion can be used to produce water-resistant and fade-resistant inks and toners for printing applications.
Alkyl silane emulsion is used in the production of personal care products to improve their water resistance and durability.

Alkyl silane emulsion can be used to produce long-lasting and water-resistant sunscreens, lotions, and creams.
Alkyl silane emulsion is used in the production of medical devices and implants to improve their biocompatibility and durability.

Alkyl silane emulsion can be used to produce water-repellent and anti-fouling coatings for medical devices and implants.
Alkyl silane emulsion is used in the production of anti-reflective coatings for optical lenses and displays.

Alkyl silane emulsion can be used to reduce glare and improve the visibility and contrast of displays and lenses.
Alkyl silane emulsion is used in the production of automotive coatings to improve their durability and resistance to environmental factors.
Alkyl silane emulsion can be used to produce water-repellent and scratch-resistant coatings for automotive surfaces.



DESCRIPTION


Alkyl silane emulsion is a type of emulsion that contains alkyl silane molecules dispersed in water.
Alkyl silanes are organic compounds that contain a silane (SiH4) group attached to a hydrocarbon chain. Alkyl silane emulsions are commonly used as adhesion promoters, water repellents, and surface modifiers in various industries.

In an emulsion, the Alkyl silane emulsions are dispersed as tiny droplets throughout the water phase, stabilized by an emulsifying agent.
This allows Alkyl silane emulsions to be easily applied to a surface as a coating, where they can form a thin layer that modifies the surface properties of the substrate.

Alkyl silane emulsions are used in a variety of applications, including coatings for glass, metal, and concrete surfaces, as well as in the production of adhesives, sealants, and composites.
Alkyl silane emulsions can improve the adhesion of coatings, reduce water absorption, and provide other beneficial properties such as chemical resistance and durability.

Alkyl silane emulsion is a type of water-based solution that contains alkyl silane molecules.
The alkyl silane molecules in the emulsion can react with surfaces to modify their properties.
Alkyl silane emulsion is commonly used as a surface modifier to improve adhesion, water repellency, and chemical resistance.

Alkyl silane emulsion is used in various industries, including automotive, construction, textile, and electronics.
Alkyl silane emulsion is often used to produce coatings, adhesives, and sealants.

Alkyl silane emulsion can also be used to improve the properties of composites and nanomaterials.
Alkyl silane emulsion can provide a cost-effective and environmentally friendly solution for surface modification.
Alkyl silane emulsion is easy to apply and can be used on a wide range of substrates, including glass, metal, concrete, and plastics.

Alkyl silane emulsion can significantly improve the durability and lifespan of coated surfaces.
The development of new formulations and applications for alkyl silane emulsion is ongoing, making it a promising material for future use.


The properties of alkyl silane emulsion can vary depending on the specific formulation and intended application, but here are some general properties:

Hydrophobicity:
Alkyl silane emulsion is known for its water-repellent properties, which can make it useful for applications where water protection is required.


Adhesion:
Alkyl silane emulsion can adhere well to a variety of substrates, including metal, glass, ceramics, and some plastics.


Chemical resistance:
Alkyl silane emulsion can exhibit good resistance to chemicals, such as acids, bases, and organic solvents.


Stability:
Alkyl silane emulsion is stable under normal conditions and can have a long shelf life if stored properly.


Low surface tension:
Alkyl silane emulsion can have a low surface tension, which can help it spread evenly over a surface and penetrate into porous substrates.


Film-forming:
Alkyl silane emulsion can form a thin film on the surface of a substrate, which can help protect it from moisture, corrosion, and other types of damage.


Compatibility:
Alkyl silane emulsion can be compatible with a variety of other chemicals and additives, which can make it useful in a range of different formulations.


Temperature resistance:
Alkyl silane emulsion can exhibit good resistance to high and low temperatures, which can make it suitable for use in extreme environments.


Low VOC:
Alkyl silane emulsion can have a low VOC (volatile organic compound) content, which can make it environmentally friendly and compliant with various regulations.


Good coverage:
Alkyl silane emulsion can provide good coverage over large areas, which can help reduce the amount of product needed for a given application.



FIRST AID


Alkyl silane emulsion is a relatively safe chemical with low toxicity, but it is still important to take appropriate safety precautions and be aware of first aid measures in case of accidental exposure.
If a person comes into contact with alkyl silane emulsion, it is important to first remove any contaminated clothing and immediately flush the affected area with large amounts of water for at least 15 minutes.

If the chemical has entered the eyes, they should be flushed with water for at least 20 minutes, ensuring that the eyelids are held open to allow water to penetrate the eyes.
If the affected person is experiencing respiratory distress, they should be immediately removed from the area and taken to a location with fresh air. If the person is unconscious or not breathing, CPR may be necessary.

It is important to seek medical attention immediately after exposure to alkyl silane emulsion, even if there are no apparent symptoms.
Medical professionals can monitor the person for any delayed or long-term effects of exposure and provide appropriate treatment if necessary.

In the case of ingestion of alkyl silane emulsion, the affected person should not induce vomiting, as this can cause further harm. Instead, they should drink plenty of water and seek medical attention immediately.

When working with alkyl silane emulsion, it is important to wear appropriate personal protective equipment (PPE), such as gloves, goggles, and respiratory protection, to minimize the risk of exposure.
It is also important to ensure proper ventilation in the work area to prevent the inhalation of vapors.


In summary, if a person is exposed to alkyl silane emulsion, they should:

Remove contaminated clothing and flush the affected area with large amounts of water for at least 15 minutes.
Flush eyes with water for at least 20 minutes if the chemical has entered the eyes.
Seek medical attention immediately, even if there are no apparent symptoms.
Wear appropriate personal protective equipment when working with the chemical.
Ensure proper ventilation in the work area to prevent inhalation of vapors.



HANDLING AND STORAGE


Handling and storage of alkyl silane emulsion is critical to ensure its stability and minimize the risk of exposure to the chemical.
Here are some guidelines for handling and storing alkyl silane emulsion:


Handling:

Wear appropriate personal protective equipment (PPE), including gloves, goggles, and respiratory protection, when handling alkyl silane emulsion.
Avoid direct contact with the chemical, and handle it in a well-ventilated area to prevent inhalation of vapors.

Use only non-sparking tools and equipment when handling the chemical to prevent fires and explosions.
Keep the chemical away from heat, sparks, and open flames.
Never eat, drink, or smoke while handling alkyl silane emulsion.


Storage:

Store alkyl silane emulsion in a cool, dry, well-ventilated area, away from sources of heat and ignition.
Keep the chemical away from incompatible substances, such as oxidizers, acids, and bases.
Store alkyl silane emulsion in its original container, tightly closed and labeled with the appropriate hazard warnings.

Ensure that containers are stored upright and secured to prevent spills or leaks.
Keep containers of alkyl silane emulsion away from direct sunlight, and protect them from physical damage.

In addition to these general guidelines, it is important to follow any specific handling and storage instructions provided by the manufacturer or supplier of the chemical. These may include information on the appropriate temperature range for storage, shelf life, and any specific hazards associated with the product.

It is also important to train employees and other individuals who handle alkyl silane emulsion on proper handling and storage procedures to minimize the risk of exposure or accidents.
This may include providing appropriate PPE, ensuring proper ventilation and emergency response procedures, and conducting regular safety audits to identify and address potential hazards.

Overall, careful handling and storage of alkyl silane emulsion is essential to ensure its safety and effectiveness in various industrial applications.



SYNONYMS


Alkyl siloxane emulsion
Alkyl-functional siloxane emulsion
Alkylalkoxysilane emulsion
Alkylpolysiloxane emulsion
Alkylsilane polymer emulsion
Alkyltrimethoxysilane emulsion
Hydrophobic alkylsilane emulsion
Silane modified emulsion
Silane modified polymer emulsion
Silane-modified siloxane emulsion
Water repellent alkyl silane emulsion
Alkoxy-functional siloxane emulsion
Alkoxy-modified silane emulsion
Alkoxy-modified siloxane emulsion
Alkyl-functional silane polymer emulsion
Alkyl-functional siloxane polymer emulsion
Alkylsilane oligomer emulsion
Alkylsilane resin emulsion
Alkylsilane siloxane copolymer emulsion
Alkylsilane terpolymer emulsion
Alkylsilyl-terminated polyether emulsion
Alkylsilyl-terminated polyurethane emulsion
Cationic alkyl silane emulsion
Ethoxy-functional siloxane emulsion
Fluorinated alkyl silane emulsion
Hydrophilic alkyl silane emulsion
Methoxy-functional siloxane emulsion
Methoxy-modified silane emulsion
Methoxy-modified siloxane emulsion
Non-ionic alkyl silane emulsion
Octyl-functional silane emulsion
Organofunctional silane emulsion
Phenyl-functional silane emulsion
Polyalkylsiloxane emulsion
Polydimethylsiloxane emulsion
Silane coupling agent emulsion
Silane-modified acrylic emulsion
Silane-modified epoxy emulsion
Silane-modified urethane emulsion
Water-resistant alkyl silane emulsion
Water-repellent silane emulsion
ALKYL(C12-C16) ALCOHOL SULFATE SODIUM SALT
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is a kind of anionic surfactant with excellent performance.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt has excellent detergency, emulsification, wetting, dispersion, densifying and foamability performance, it is easy to dissolve in water.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salts are a widely used class of anionic surfactants.

CAS Number: 73296-89-6
EINECS Number: 277-362-3

Synonyms: Sulfuric acid, mono-C12-16-alkyl esters, sodium salts, 73296-89-6, Alkyl(C12-C16)alcohol sulfate sodium salt, DTXSID40104773, EC 277-362-3, EINECS 277-362-3,Sodium Laureth-7 Sulfate;Sodium Laureth-8 Sulfate;Sodium Laureth-5 Sulfate;Sodium lauryl ether sulphate;AES;Sodium Lauyl ether Sulphate;sodium 2-(2-dodecyloxyethoxy)ethyl sulphate;;Diethylene glycol monolauryl ether sodium sulfate;PEG-(1-4) Lauryl ether sulfate, sodium salt;Poly(oxy-1,2-ethanediyl), alpha-sulfo-omega(dodecyloxy)-, sodium salt;Polyethylene glycol (1-4) lauryl ether sulfate, sodium salt;Polyoxyethylene (1-4) lauryl ether sulfate, sodium salt;Sodium laureth sulfate;Sodium polyoxyethylene lauryl sulfate;2-(2-Dodecyloxyethoxy)ethyl sodium sulfate.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt, commonly referred to as Sodium Alkyl Sulfate, is a class of anionic surfactants widely used in various cleaning and personal care products.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is a sodium salt of the sulfate ester of long-chain alcohols ranging from C12 to C16
Consists of a hydrophobic Alkyl(C12-C16) Alcohol Sulfate Sodium Salt and a hydrophilic sulfate group, making it an effective surfactant.

They are used in household cleaning products, personal care products, institutional cleaners and industrial cleaning processes, and as industrial process aids in emulsion polymerisation and as additives during plastics and paint production.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt used in household cleaning products, the scope of HERA, include laundry detergents, hand dishwashing liquids, and various hard surface cleaners.
As well as has wide compatibility, favorable hard-water resistant and high-biodegradation ability and low irritation to skin and eye.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt effective at removing dirt and grease.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used for its ability to cut through grease and food residues.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt commonly found in all-purpose cleaners and surface cleaners.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt provides lathering and cleansing properties.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt helps to emulsify oils and dirt, allowing them to be rinsed away.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt acts as a foaming agent to help distribute the paste evenly in the mouth.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used in emulsion polymerization processes.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used in textile and paper processing for its wetting and emulsifying properties.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt included in formulations to create foam and improve texture.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt reduces surface tension, allowing for better interaction between water and oils/grease.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt creates a rich lather, which is desirable in many personal care products.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt efficient at removing dirt, oil, and other impurities.

Can cause irritation, especially with prolonged exposure or in individuals with sensitive skin.
Using lower concentrations and combining with other milder surfactants.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt an be irritating to the eyes.

Redness, watering, and stinging sensation.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt avoiding direct contact with eyes and ensuring proper formulation in products.
Harmful if swallowed in significant quantities.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt nausea, vomiting, and gastrointestinal distress.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt keeping products containing the compound out of reach of children and not using it in products meant for ingestion.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt readily biodegradable, but high concentrations can be toxic to aquatic life.

Proper disposal and treatment of wastewater to avoid environmental contamination.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt store in a cool, dry place, away from direct sunlight and moisture.
Use appropriate Alkyl(C12-C16) Alcohol Sulfate Sodium Salt such as gloves and safety goggles when handling concentrated forms of the substance.

Contain and clean up spills immediately, avoiding release into the environment.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt ubject to regulations by agencies such as the EPA, OSHA, and similar organizations globally to ensure safe use and disposal.
Products containing Alkyl(C12-C16) Alcohol Sulfate Sodium Salt must be properly labeled to inform users of potential hazards and safe handling instructions.

Boiling point: 187-208��� at 100.7-101kPa
vapor pressure: 0-97Pa at 20-25℃
form: Powder
LogP: -2.42--2.1 at 20℃
Surface tension 29.9-31.9mN/m at 1g/L and 23℃
Dissociation constant: 1.73-2.15 at 20℃

In textile, printing and dyeing, oil and leather industries, Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is the lubricant, dyeing agent, cleaner, foaming agent and degreasing agent.
Usually appears as a white or off-white powder or as a clear, viscous liquid in its aqueous form.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt highly soluble in water, forming clear solutions.

Significantly reduces the surface tension of water, enhancing its wetting and spreading properties.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt, enhances soil removal and suspension.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt uts through grease and food residues efficiently.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used in sprays and solutions for cleaning various surfaces like countertops, floors, and walls.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt creates rich foam that helps distribute the product evenly through hair.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt effective at removing oils and residues from the scalp and hair.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt provides a luxurious lather and enhances the sensory experience.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt helps emulsify and remove dirt and oils from the skin.
Acts as a foaming agent to help in the mechanical removal of plaque and food particles.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt ensures even distribution of the paste in the oral cavity.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used as a wetting agent and emulsifier in textile processing.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt assists in dyeing and finishing processes.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used in paper manufacturing to improve the wetting and penetration of chemical treatments.
Acts as an emulsifier in the production of synthetic latexes and other polymer dispersions.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt breaks down and removes dirt, oil, and grease from fabrics.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt enhances the cleaning power of detergents, making them more effective in both hard and soft water.
Often combined with other surfactants, builders, and enzymes to improve overall cleaning efficiency.
Removes food residues, grease, and oils from dishes and utensils.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt provides rich, stable foam that aids in the mechanical action of cleaning.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt works well with other ingredients like enzymes and fragrances to create a balanced formulation.
Effective in cleaning a wide range of surfaces, including countertops, floors, and walls.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt elps to lift and suspend dirt and grime for easy removal.
Readily dissolves in water, making it easy to formulate into liquid cleaners.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt provides rich foam, improving the user experience and ensuring even distribution.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt removes sebum, dirt, and styling product residues from hair and scalp.
Often used alongside conditioning agents to prevent dryness and maintain hair health.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt efficiently removes oils, sweat, and impurities from the skin.

Lathering: Creates a luxurious lather, enhancing the sensory feel of the product.
Frequently formulated with moisturizers to counteract potential drying effects.
Helps to distribute the paste evenly in the mouth and improves the cleaning process.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt assists in the mechanical removal of plaque and food particles from teeth and gums.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt lowers the surface tension of water, allowing it to penetrate fabrics more effectively.
Helps in the dyeing and finishing processes by emulsifying oils and other materials.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used in scouring agents to remove oils, waxes, and other impurities from fabrics before dyeing.
Improves the penetration and effectiveness of chemicals used in paper production.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used in recycling processes to help remove ink from paper fibers.

Stabilizes emulsions in the production of synthetic latexes and other polymer dispersions.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt enhances the formation and stability of polymer particles.
Wear protective gloves/protective clothing/eye protection/face protection.

Rinse cautiously with water for several minutes.
Remove contact lenses if present and easy to do. Continue rinsing.
If skin irritation occurs: Get medical advice/attention.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used appropriate personal protective equipment to avoid contact with skin and eyes.
Ensure adequate ventilation in work areas.
Avoid creating dust or aerosols.

Store in a cool, dry place away from direct sunlight and incompatible materials (e.g., strong oxidizers).
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt keep containers tightly closed when not in use.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt environmental Impact and Biodegradability.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salts are toxic to aquatic organisms, with potential long-term adverse effects in aquatic environments.
They are considered readily biodegradable, meaning they break down relatively quickly under environmental conditions.
However, their persistence in high concentrations can still pose risks to aquatic life.

Discharges to water bodies should be minimized and treated to comply with local environmental regulations.
In response to concerns about skin irritation, some formulations combine Sodium Alkyl Sulfates with milder surfactants such as Sodium Cocoamphoacetate or Cocamidopropyl Betaine to reduce potential irritation.
Development of more eco-friendly and sustainable surfactants derived from renewable resources is ongoing.

These alternatives aim to offer similar performance with reduced environmental and health impacts.
Store in a cool, dry place away from direct sunlight and moisture.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt keep containers tightly closed to prevent moisture absorption and contamination.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt tore away from strong oxidizing agents and acids to prevent hazardous reactions.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt use absorbent materials like sand or vermiculite to contain spills.
Collect spilled material and dispose of it according to local regulations.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt prevent the material from entering waterways and sewers.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salts are readily biodegradable, breaking down into harmless substances under environmental conditions.
However, their high concentrations can be toxic to aquatic life.

They pose a risk to aquatic organisms, emphasizing the need for proper wastewater treatment and disposal practices.
Compliance with environmental regulations ensures minimal impact on the ecosystem.
This includes adhering to guidelines set by agencies such as the EPA and the European Chemicals Agency (ECHA).

To reduce irritation, Alkyl(C12-C16) Alcohol Sulfate Sodium Salts are often combined with milder surfactants such as betaines or amides.
Incorporating moisturizing agents like glycerin or conditioners helps mitigate the drying effects of these surfactants.
Ensuring the product has a skin-friendly pH to prevent irritation and maintain skin barrier integrity.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt development of surfactants from renewable resources aims to reduce environmental impact and enhance sustainability.
Innovations in green chemistry focus on creating safer and more environmentally friendly surfactants with similar efficacy.
Continuous improvement in formulations seeks to maximize the benefits of Alkyl(C12-C16) Alcohol Sulfate Sodium Salts while minimizing potential adverse effects.

Uses:
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is widely used in liquid detergent, such as hair and bath shampoo, dish detergents, bubble bath and hand washing, complex soap etc.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt can also be used in washing powder and detergent for heavy dirty.
Using Alkyl(C12-C16) Alcohol Sulfate Sodium Salt to replace LABSA, phosphate can be saved or reduced, and general dosage of active matter is reduced.

Effective in removing dirt, stains, and odors from fabrics.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt cuts through grease and food residues on dishes and utensils.
Suitable for cleaning various surfaces like countertops, floors, and walls.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt provides lather and cleansing action for hair and scalp.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt leanses and refreshes the skin, often providing a luxurious lather.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt aids in the mechanical removal of plaque and food particles from teeth and gums.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used as a wetting agent and emulsifier in textile processing.
Helps in the production of paper by improving the wetting and penetration of chemicals.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt acts as a surfactant in the production of synthetic latexes and polymer dispersions.

Included in formulations to create foam in various cosmetic products.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used in facial cleansers, makeup removers, and other cleansing formulations.
Effective in removing oil and grease from industrial equipment and surfaces.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used in car wash soaps and cleaners for effective cleaning of vehicles.
Incorporated into disinfectant formulations for cleaning and sanitizing surfaces in healthcare facilities.
Utilized for cleaning and maintaining cleanliness in commercial and institutional settings.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used in animal hygiene products such as teat dips and udder sanitizers.
Incorporated into agricultural formulations for cleaning and disinfecting equipment and facilities.
Included in hair styling gels, mousses, and sprays to provide hold and texture.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt i used in shampoos and conditioners formulated for color-treated hair to cleanse without stripping color.
Found in liquid hand soaps and hand sanitizers for effective cleansing and germ-killing properties.
Included in formulations for intimate hygiene products to maintain cleanliness and freshness.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is utilized in pet shampoos and grooming products to cleanse and condition the fur and skin of pets.
Incorporated into pet wipes for quick and convenient cleaning of pets' paws, fur, and other areas.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used in industrial degreasers for cleaning heavy machinery, engines, and equipment in manufacturing and automotive industries.

Applied in degreasing solutions for cleaning metal parts and components during manufacturing processes.
Added to drilling mud formulations used in oil and gas exploration and production for lubrication and suspension of solids.
Utilized in chemical flooding and water injection processes to improve oil recovery from reservoirs.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used as an admixture in concrete formulations to improve workability, reduce water demand, and enhance strength and durability.
Added to grout and mortar mixes for tile installation and masonry work to improve flow and adhesion properties.
Included in adhesive formulations for bonding various construction materials such as wood, metal, and plastics.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used in sealant and caulk formulations for sealing gaps, joints, and cracks in buildings and structures.
Employed as a flocculating agent in water treatment processes to help coagulate and settle suspended particles for easier removal.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used in scale inhibitor formulations to prevent the formation of scale deposits in water systems and equipment.

Included in formulations for car wash soaps to remove dirt, road grime, and contaminants from vehicle surfaces.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used in wheel and tire cleaning products to dissolve brake dust, grease, and road tar.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt s utilized in formulations for cleaning boat hulls to remove algae, barnacles, and marine growth.

Formulated into cleaners for boat decks and surfaces to remove salt deposits and stains.
Incorporated into sanitizers for cleaning food processing equipment, utensils, and surfaces to maintain hygiene standards.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used in CIP systems to clean and sanitize processing equipment and pipelines without disassembly.

Added to pool cleaning solutions to remove algae, bacteria, and organic contaminants from pool water and surfaces.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt utilized in spa water clarifiers to improve water clarity by removing suspended particles.
Formulated into degreasing solutions for cleaning metal surfaces prior to painting, coating, or plating.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt is used in rust removal products to dissolve and remove rust from metal surfaces.
Included in disinfectant sprays and wipes for killing germs and bacteria on household surfaces.
Formulated into all-purpose cleaners with disinfectant properties for general household cleaning.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt added to pet shampoos and grooming products for cleaning and conditioning the fur and skin of pets and animals.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt utilized in disinfectant solutions for cleaning and disinfecting livestock facilities, equipment, and enclosures.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt used in solutions for disinfecting medical instruments, equipment, and surfaces in healthcare settings.

Included in hand sanitizers and antiseptic solutions for hand hygiene and infection control.
Formulated into floor cleaning solutions for removing dirt, stains, and scuff marks from various floor surfaces.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt s used in restroom cleaning products for removing soap scum, mineral deposits, and stains from toilets, sinks, and tiles.

Utilized in greenhouse cleaning solutions for removing dirt, algae, and residues from greenhouse structures and surfaces.
Incorporated into formulations for cleaning and disinfecting agricultural equipment, tools, and facilities.

Safety Profile:
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt can cause skin irritation, particularly in individuals with sensitive skin or prolonged exposure.
Symptoms may include redness, itching, and dermatitis.
Direct contact with concentrated solutions or prolonged exposure to diluted solutions may exacerbate irritation.

Contact with the eyes can cause irritation, redness, and discomfort.
In severe cases or with prolonged exposure, Alkyl(C12-C16) Alcohol Sulfate Sodium Salt may lead to eye damage or corneal injury.
Rinse thoroughly with water if contact occurs and seek medical attention if irritation persists.

Inhalation of dust or aerosols may cause respiratory irritation, coughing, or shortness of breath.
This hazard is more relevant in industrial settings where airborne particles may be generated during handling or processing.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt can cause gastrointestinal irritation, nausea, vomiting, and diarrhea.

Swallowing large amounts may result in more severe symptoms and require medical attention.
Alkyl(C12-C16) Alcohol Sulfate Sodium Salt's important to keep products containing this substance out of reach of children and to avoid ingestion.

Alkyl(C12-C16) Alcohol Sulfate Sodium Salt can be harmful to aquatic life if released into water bodies in high concentrations.
It may exhibit acute or chronic toxicity to aquatic organisms, depending on the concentration and exposure duration.


ALLANTOIN
1-(2,5-dioxoimidazolidin-4-yl)urée; No CAS 97-59-6; Alantoína, allantoina, ALLANTOIN,alantoin, Nom chimique : Urea, (2,5-dioxo-4-imidazolidinyl)-; Uréidohydantoïne; Glyoxyldiuréide; Hémocane; 5-uréidohydantoïne; N° EINECS/ELINCS : 202-592-8, L'allantoïne se présente sous la forme d'une poudre cristalline blanche. Il s'agit d'un composé azoté que l'on retrouve aussi bien dans le milieu végétal ou animal (dans l'urine des veaux). Elle peut être aussi obtenue synthétiquement à partir d'acide urique. Dans les cosmétiques, l'allantoïne est utilisée pour ses propriétés astringentes, anti-irritantes, anti-inflammatoires, cicatrisantes et hydratantes. Elle sert aussi dans le traitement de l'hypersensibilité dentinaire. L'allantoïne Écouter est un composé chimique azoté, de formule C4H6N4O3, d’origine organique ou végétale découvert par Louis-Nicolas Vauquelin dans le liquide amniotique de la vache ; il a été trouvé également dans l'urine du veau (Friedrich Wöhler) puis chez de nombreux mammifères à l'exception des grands primates (dont l'Homme). Bien qu'il soit possible d'extraire l'allantoïne à partir du mucus de certains gastéropodes (ex : escargots), l'industrie cosmétique privilégie la synthèse chimique pour sa production2. L'allantoïne est en effet le produit de l'oxydation de l'acide urique. Parmi les végétaux, on en trouve dans les racines de la grande consoude et dans les graines de céréales. C'est un uréide oxyglycollique, qui cristallise en prismes clinorhombiques, brillants, incolores, peu solubles dans l'eau, que la barite décompose à l'ébullition en ammoniaque et en oxalate de baryum.En cosmétique, on en trouve principalement dans les soins de la peau et les produits de maquillage, mais aussi dans les dentifrices, shampoings, crèmes à raser, rouges à lèvres, etc. L'allantoïne n'est pas antiseptique. En raison de possibles interactions, les préparations contenant de l'allantoïne ne doivent pas être stockées dans des récipients en métal.
ALLANTOIN
DESCRIPTION:
Allantoin is a naturally-occurring chemical compound.
In its pure form, Allantoin is a white, odorless powder.
Many plants contain allantoin, such as comfrey, horse chestnut, and bearberry.

CAS Number: 97-59-6
EC Number: 202-592-8
IUPAC Name: (2,5-dioxoimidazolidin-4-yl)urea

Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets.
In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l.
During exercise, the plasma allantoin concentration rapidly increases about two fold and remains elevated. In human muscle, urate is oxidized to allantoin during such exercise.

The concentration of allantoin in muscles increases from a resting value of about 5000 ug/kg to about 16000 ug/kg immediately after short-term exhaustive cycling exercise.
More specifically, allantoin is a diureide of glyoxylic acid that is produced from uric acid.
Allantoin is a major metabolic intermediate in most organisms.

Allantoin is found in OTC cosmetic products and other commercial products such as oral hygiene products, in shampoos, lipsticks, anti-acne products, sun care products, and clarifying lotions.
Allantoin has also demonstrated to ameliorate the wound healing process in some studies.









Additionally, some mammals excrete allantoin in urine.
While manufacturers can extract allantoin from plants, they prefer making Allantoin from urea and glyoxylic acid.

Companies add allantoin to many personal care products due to its ability to protect the skin from irritation.
Allantoin temporarily stops irritants from inflaming wounds or sensitive skin.
There are different forms of allantoin, in addition to its pure form.

These include:
• allantoin ascorbate
• allantoin biotin
• allantoin panthenol

Allantoin is a chemical compound with formula C4H6N4O3.
Allantoin is also called 5-ureidohydantoin or glyoxyldiureide.
Allantoin is a diureide of glyoxylic acid.

Allantoin is a major metabolic intermediate in most organisms including animals, plants and bacteria.
Allantoin is produced from uric acid, which itself is a degradation product of nucleic acids, by action of urate oxidase (uricase).
The occurs as a natural mineral compound (IMA symbol Aan).

Allantoin is a skin active ingredient with keratolytic, moisturizing, soothing, anti-irritant properties, promotes the renewal of epidermal cell and accelerates wounds healing.
Allantoin is safe and non-irritant, highly compatible with the skin and with cosmetic raw materials.
Allantoin enjoys a long history of use in cosmetics and topical pharmaceuticals with no findings of toxicity or adverse reactions.
Comply with CTFA and JSCI requirements.


MODE OF ACTION:
The beneficial effects on the skin of Allantoin were well documented.
Allantoin is a mild keratolytic agent that dissolves the intercellular cement that holds the cornified cells together, helping the natural desquamation of stratum corneum and increasing skin smoothness.
The moisturizing effect results from its ability to increase the water bounded to the intercellular matrix and keratin, thereby softening skin and making the skin look healthier.

The soothing, anti-irritant and skin protectant effect is due to the ability of Allantoin to form complexes and neutralize many irritant and sensitizing agents.
Allantoin enhances epidermal cell-proliferation, promotes the regeneration of damaged epitelium and accelerates wound healing.


ORIGIN OF ALLANTOIN:
Allantoin is a metabolic intermediate of a wide variety of organisms: from bacteria, to vegetals and animals.
Allantoin was found in many plants, and particularly in the leaves and roots of comfrey (Symphytum officinale), an herb of family Boraginacee.
The roots and leaves of this herb contain from 0.6 to 1% Allantoin and have a long history of use in the treatment of wounds in form of poultices and decoctions.

Allantoin is the end product of purine degradation in Mammalians (except Primates) and derives from the oxidation of uric acid.
Allantoin can’t be extracted from animals with industrial advantages, thus all internet alerts on the animal origin of Allantoin are completely unsubstantiated.
Allantoin CTFA manufactured by Akema is the natural-identical compound fully obtained via a chemical process that make no use of substances of animal origin.



PROPERTIES AND STABILITY OF ALLANTOIN:
Allantoin is a heterocyclic compound derived from purine.
Allantoin is an odourless white powder, soluble in water to 0.5%, very slightly soluble in alcohols, insoluble in oils and apolar solvents.
Allantoin is stable in the pH range 3-8 and to 80°C prolonged heating.
Allantoin is fully compatible with cosmetic ingredients and with anionic, non-ionic, cationic systems.


BACKGROUND INFORMATION ABOUT ALLANTOIN:
Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets Label.
In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l.
During exercise, the plasma allantoin concentration rapidly increases about two fold and remains elevated Label.

In human muscle, urate is oxidized to allantoin during such exercise Label.
The concentration of allantoin in muscles increases from a resting value of about 5000 ug/kg to about 16000 ug/kg immediately after short-term exhaustive cycling exercise Label.
More specifically, allantoin is a diureide of glyoxylic acid that is produced from uric acid.

It is a major metabolic intermediate in most organisms.
Allantoin is found in OTC cosmetic products and other commercial products such as oral hygiene products, in shampoos, lipsticks, anti-acne products, sun care products, and clarifying lotions 4.
Allantoin has also demonstrated to ameliorate the wound healing process in some studies



HISTORY OF ALLANTOIN:
Allantoin was first isolated in 1800 by the Italian physician Michele Francesco Buniva (1761–1834) and the French chemist Louis Nicolas Vauquelin, who mistakenly believed it to be present in the amniotic fluid.
In 1821, the French chemist Jean Louis Lassaigne found it in the fluid of the allantois; he called it "l'acide allantoique".
In 1837, the German chemists Friedrich Wöhler and Justus Liebig synthesized it from uric acid and renamed it "allantoïn".

Animals:
Named after the allantois (an amniote embryonic excretory organ in which it concentrates during development in most mammals except humans and other hominids), it is a product of oxidation of uric acid by purine catabolism.
After birth, it is the predominant means by which nitrogenous waste is excreted in the urine of these animals.
In humans and other higher apes, the metabolic pathway for conversion of uric acid to allantoin is not present, so the former is excreted.

Recombinant rasburicase is sometimes used as a drug to catalyze this metabolic conversion in patients.
In fish, allantoin is broken down further (into ammonia) before excretion.
Allantoin has been shown to improve insulin resistance when administered to rats and to increase lifespan when administered to the nematode worm Caenorhabditis elegans.

Bacteria:
In bacteria, purines and their derivatives (such as allantoin) are used as secondary sources of nitrogen under nutrient-limiting conditions.
Their degradation yields ammonia, which can then be utilized.
For instance, Bacillus subtilis is able to utilize allantoin as its sole nitrogen source.



Mutants in the B. subtilis pucI gene were unable to grow on allantoin, indicating that it encodes an allantoin transporter.
In Streptomyces coelicolor, allantoinase (EC 3.5.2.5) and allantoicase (EC 3.5.3.4) are essential for allantoin metabolism.
In this species the catabolism of allantoin, and the subsequent release of ammonium, inhibits antibiotic production (Streptomyces species synthesize about half of all known antibiotics of microbial origin).

APPLICATIONS OF ALLANTOIN:
Allantoin is present in botanical extracts of the comfrey plant and in the urine of most mammals.
Chemically synthesized bulk allantoin, which is chemically equivalent to natural allantoin, is safe, non-toxic, compatible with cosmetic raw materials and meets CTFA and JSCI requirements.
Over 10,000 patents reference allantoin.

Cosmetics:
Manufacturers may use allantoin as an ingredient in over-the-counter cosmetics.

Pharmaceuticals:
Allantoin is frequently present in toothpaste, mouthwash, and other oral hygiene products, in shampoos, lipsticks, anti-acne products, sun care products, and clarifying lotions, various cosmetic lotions and creams, and other cosmetic and pharmaceutical products.

Biomarker of oxidative stress:
Since uric acid is the end product of the purine metabolism in humans, only non-enzymatic processes with reactive oxygen species will give rise to allantoin, which is thus a suitable biomarker to measure oxidative stress in chronic illnesses and senescence


Allantoin is suitable for any personal care application.
Its use notably increases the performance of every cosmetic preparation: used at low levels on intact skin gives a smooth and healthy appearance; used on irritated, chapped and cracked skin provide relief from pain and promote healing. Allantoin is also useful as only active ingredient.

The many cosmetic applications include:
• Body and face care: tonics, gels, creams, lotions, wipes.
• Hand-care: gels, lotions, creams.
• Shaving-care: shaving soaps, aftershaves, gels, lotions, creams.
• Baby-care: diaper rash, bath products, gels, lotions, creams, powders, wipes.
• Lips-care: sticks, creams.
• Sun-care: sunscreens, aftersuns, suntans, gels, lotions, creams.
• Hair products: shampoos, tonics.
• Bath products: shower gels, bubble baths, intimate, powders, wipes.
• Oral preparations: toothpastes, mouthwashes.


USES OF ALLANTOIN:

Allantoin is used as a moisturizer to treat or prevent dry, rough, scaly, itchy skin and minor skin irritations (such as diaper rash, skin burns from radiation therapy).
Emollients are substances that soften and moisturize the skin and decrease itching and flaking.
Some products (such as zinc oxide, white petrolatum) are used mostly to protect the skin against irritation (such as from wetness).

Dry skin is caused by a loss of water in the upper layer of the skin.
Emollients/moisturizers work by forming an oily layer on the top of the skin that traps water in the skin.
Petrolatum, lanolin, mineral oil and dimethicone are common emollients.
Humectants, including glycerin, lecithin, and propylene glycol, draw water into the outer layer of skin.

Many products also have ingredients that soften the horny substance (keratin) that holds the top layer of skin cells together (including urea, alpha hydroxy acids such as lactic/citric/glycolic acid, and allantoin).
This helps the dead skin cells fall off, helps the skin keep in more water, and leaves the skin feeling smoother and softer.

HOW TO USE ALLANTOIN:
Use Allantoin as directed.
Some products require priming before use.
Follow all directions on the product package.
If you have any questions, ask your doctor or pharmacist.

Some products need to be shaken before use.
Check the label to see if you should shake the bottle well before using.
Apply to the affected areas of the skin as needed or as directed on the label or by your doctor.
How often you apply the medication will depend on the product and your skin condition.
To treat dry hands, you may need to use the product every time you wash your hands, applying it throughout the day.

If you are using this product to help treat diaper rash, clean the diaper area well before use and allow the area to dry before applying the product.

If you are using this product to help treat radiation skin burns, check with radiation personnel to see if your brand can be applied before radiation therapy.

Follow all the directions on the label for proper use.
Apply to the skin only.
Avoid sensitive areas such as your eyes, inside your mouth/nose, and the vaginal/groin area, unless the label or your doctor directs you otherwise.

Check the label for directions about any areas or types of skin where you should not apply the product (such as on the face, any areas of broken/chapped/cut/irritated/scraped skin, or on a recently shaved area of the skin).
Consult your doctor or pharmacist for more details.

Use this medication regularly to get the most benefit from it.
Most moisturizers need water to work well.
Apply the product after bathing/showering while the skin is still damp.

For very dry skin, your doctor may instruct you to soak the area before using the product.
Long, hot, or frequent bathing/washing can worsen dry skin.

If your condition lasts or gets worse, or if you think you may have a serious medical problem, get medical help right away.


BENEFITS AND USES OF ALLANTOIN:
Allantoin has many skin care benefits, including:

Reducing irritation:
One 2015 studyTrusted Source compared the anti-irritant effects of pure allantoin and comfrey extract, which also contains naturally-occurring allantoin.
The researchers found that both substances reduced irritation.

However, the comfrey extract was more effective than pure allantoin.
This suggests that a combination of compounds in comfrey root has a beneficial effect on irritation.

Child eczema:
Atopic dermatitis, or atopic eczema, causes inflamed, itchy, and dry skin.
It is especially important to soothe these symptoms in young children to prevent them from scratching and breaking the skin.

Allantoin, aloe vera, and oatmeal all have anti-inflammatory properties, which may make them useful additions to a treatment regimen for child eczema alongside medications.

Acne:
Benzoyl peroxide is a first-line acne treatment.
However, its drying effect on the skin may accelerate aging and discourage people from using it.
This may lead to worsened symptoms and more acne scarring.

In a small 2020 study of 31 women, participants responded well to a new acne regimen containing allantoin and a blend of ceramides.
Overall, they noticed a reduction in acne symptoms and improved skin barrier function.

Scars:
A combination of allantoin and onion extract has been available as a scar-treatment gel for several decades.
Proponents claim onion extract has anti-inflammatory properties, whereas allantoin is hydrating and epithelizing.
This means it helps to grow new skin cells.

A 2018 study including 125 participants found that their scars were less noticeable after wearing an allantoin and onion extract patch after skin surgery.
This supports the theory that allantoin has scar healing properties.

Wound healing:
Pectin and allantoin already have many uses in the pharmaceutical and beauty industry.
However, both show promise for aiding wound healing.
A 2020 study found that pectin-allantoin films sped up healing time by 25% in rats with skin wounds.

Studies that investigate the wound healing properties of allantoin tend to use animals, so the results may not apply to humans.
That said, the results of this study are promising and suggest that pectin and allantoin could have uses in wound care.


Moisturizes:
Allantoin acts as an emollient that keeps your skin moisturized and prevents dryness and irritation.

Soothes skin:
Allantoin has the additional functionality of being a calming agent.
It soothes and protects the skin by forming complexes with irritant and sensitizing agents, according to Herrmann.
Improves skin-healing:
Herrmann says it has been noted to help soothe injured skin and promote wound healing and is often used to treat skin irritation and rashes.
Exfoliates:
Herrmann adds that allantoin is also keratolytic, which means it exfoliates dead skin cells.
As explained by Shamban, it helps desquamation, the shedding of the outermost membrane or layer of tissue from the inside out.

Hydrates:
Shamban says its keratolytic property can increase the water contents of cells, therefore, fighting against the damage of transepidermal water loss (TEWL) in the dermis, which keeps the skin looking plump and youthful.
"Think of it as almost the expansion of a sponge when wet, holding the maximum amount of liquid," she says.

Improves skin dullness:
Allantoin promotes cell proliferation and supports overall "remodeling," as Shamban puts it.
"If the skin is stressed by the usual and customary list of offenders, then the skin is going to try to repair itself as opposed to having more cells turn over," she explains.
"What we want to do with the epidermis is to have it constantly exfoliating itself and having more cells be produced because that’s how you get a faster transit time of the epidermal cells.

As people get older, then that transit time from the base layer of the epidermis to the top layer takes longer, and also the skin is stressed, and those are some of the causes of dull, dry skin, too.
This is going to help with that cell proliferation."

Smoothes skin:
Herrmann says removing surface dead skin cells (stratum corneum), also helps keep the skin smooth and soft.
Rejuvenates the cells: Although it's gentle, it can still be an effective anti-aging ingredient.
"Allantoin is highly beneficial in facilitating collagen synthesis," Shamban says.
"As it stimulates the fibroblasts (cells responsible for producing collagen), it also boosts extracellular matrix synthesis, which is why it is a strong rejuvenator."







PRODUCTS OF ALLANTOIN:
There are a variety of products that contain allantoin, including:
• Haircare products
• shampoo
• conditioner
• hair serums
• hair masks
• Makeup products
• mascara
• eye shadow
• concealer
• lipstick
• eyeliner
• foundation
• Skincare products
• facial moisturizers
• serums
• hand creams
• foot creams
• body washes
• makeup removers
• Infant products
• baby sunscreen
• baby shampoo
• baby soap
• baby lotion



HOW TO USE ALLANTOIN:
Before using a product that contains allantoin, it is best to perform a patch test.
This can tell someone if the product is safe for them to use.

To do this, apply a small amount of the product to a patch of skin.
For example, a person might apply a moisturizer to a patch on the inside of the arm.
If no irritation occurs in the next 24 hours, it is likely safe to use.

How a person uses allantoin-containing products depends on the type of product, instructions for use, and what they are trying to achieve.
For example:

Cleansers:
People may wish to use allantoin within a gentle, pH-balanced cleanser suitable for sensitive skin.
Gently massage or lather the cleanser on the face before washing away and drying with a clean towel.
Avoid the eyes and any areas of broken skin.

Toners or serums.
Apply these products after cleansing and before applying thicker moisturizers.
Again, avoid damaged skin.

Allow to dry or sink in before moving on to other steps.
Creams and lotions.
Apply these last in the routine, concentrating on areas of dryness or irritation.



SAFETY INFORMATION ABOUT ALLANTOIN:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product





CHEMICAL AND PHYSICAL PROPERTIES OF ALLANTOIN:
Chemical formula C4H6N4O3
Molar mass 158.117 g•mol−1
Appearance colourless crystalline powder
Odor odorless
Density 1.45 g/cm3
Melting point 230 °C (446 °F; 503 K) (decomposes)
Boiling point 478 °C (892 °F; 751 K)
Solubility in water 0.57 g/100 mL (25 °C)
4.0 g/100 mL (75 °C)
Solubility soluble in alcohol, pyridine, NaOH
insoluble in ethyl ether
log P −3.14
Acidity (pKa) 8.48


SYNONYMS OF ALLANTOIN:
Allantoin
Herpecin L
Herpecin-L
HerpecinL
Sebical
Woun'dres
allantoin
97-59-6
5-Ureidohydantoin
Glyoxyldiureide
1-(2,5-dioxoimidazolidin-4-yl)urea
Cordianine
Glyoxyldiureid
Allantol
Sebical
Alantan
AVC/Dienestrolcream
Urea, (2,5-dioxo-4-imidazolidinyl)-
Psoralon
Septalan
Hydantoin, 5-ureido-
Cutemol emollient
Uniderm A
(2,5-Dioxo-4-imidazolidinyl)urea
(2,5-dioxoimidazolidin-4-yl)urea
Glyoxylic(acid) diureide
DL-Allantoin
Caswell No. 024
Glyoxylic diureide
NSC 7606
5-Ureido-2,4-imidazolidindion
Alwextin
Herpecin L
CCRIS 1958
2,5-Dioxo-4-imidazolidinyl-urea
(+/-)-Allantoin
N-(2,5-Dioxo-4-imidazolidinyl)urea
C4H6N4O3
EPA Pesticide Chemical Code 085701
Allantoin [USAN:BAN]
4-ureido-2,5-Imidazolidinedione
Idelalisib metabolite m1a
AI3-15281
NSC-7606
Fancol TOIN
5-Ureidohydrantoin
EINECS 202-592-8
BRN 0102364
5-Ureido-2,4-imidazolidindione
DTXSID3020043
UNII-344S277G0Z
CHEBI:15676
HSDB 7490
NSC7606
Allantoin (JAN/USP)
N-(2,5-dioxoimidazolidin-4-yl)urea
344S277G0Z
allantion
97-59-6 (racemic)
DTXCID0043
MLS000737882
5377-33-3
Sd 101
Allantoin [USAN:USP:BAN:JAN]
EC 202-592-8
5-25-15-00338 (Beilstein Handbook Reference)
DL-ALLANTOIN-5-13C; 1-15N
urea, N-(2,5-dioxo-4-imidazolidinyl)-
ALLANTOIN (II)
ALLANTOIN [II]
ALLANTOIN (MART.)
ALLANTOIN [MART.]
D00121
ALLANTOIN (USP-RS)
ALLANTOIN [USP-RS]
ALLANTOIN (EP MONOGRAPH)
ALLANTOIN [EP MONOGRAPH]
ALLANTOIN (USP MONOGRAPH)
ALLANTOIN [USP MONOGRAPH]
Ureidohydantoin
N-[2,5-dioxoimidazolidin-4-yl]urea
SMR000528073
SR-01000766252
MFCD00005260
Alantoina
Hemocane
CAS-97-59-6
Prestwick_11
NCGC00016358-01
Allation,(S)
5-ureido-Hydantoin
Allantoin (8CI)
Spectrum_001078
ALLANTOIN [JAN]
ALLANTOIN [MI]
ALLANTOIN [HSDB]
ALLANTOIN [INCI]
ALLANTOIN [USAN]
Allantoin, (.+.)-
Prestwick0_000002
Prestwick1_000002
Prestwick2_000002
Prestwick3_000002
Spectrum2_000219
Spectrum3_000876
Spectrum4_000716
Spectrum5_001526
ALLANTOIN [VANDF]
bmse000437
D01HNL
ALLANTOIN [WHO-DD]
SCHEMBL3208
Oprea1_621175
BSPBio_000003
BSPBio_002551
KBioGR_001271
KBioSS_001558
MLS002473300
Allantoin, analytical standard
DivK1c_000281
SPECTRUM1500801
SPBio_000237
SPBio_001924
BPBio1_000005
CHEMBL593429
SD 101 [WHO-DD]
5-Ureidohydantoin;Glyoxyldiureide
HMS500O03
KBio1_000281
KBio2_001558
KBio2_004126
KBio2_006694
KBio3_002051
Allantoin, >=98.0% (N)
NINDS_000281
Urea,5-dioxo-4-imidazolidinyl)-
HMS1568A05
HMS1921I10
HMS2092K16
HMS2095A05
HMS2268N08
HMS3712A05
HMS3885M08
Pharmakon1600-01500801
AMY13912
BCP31832
component of Skin-balm (Salt/Mix)
HY-N0543
2,5-Imidazolidinedione, 4-ureido-
Tox21_110395
Tox21_202087
Tox21_302912
BBL027508
CCG-39781
NSC757792
s3856
STL373778
AKOS000120642
AKOS016038547
Tox21_110395_1
CS-7741
DB11100
LS-7181
NSC-757792
SDCCGMLS-0066595.P001
IDI1_000281
USEPA/OPP Pesticide Code: 085701
Allantoin, p.a., 98.5-101.0%
N-(2,5-Dioxo-4-imidazolidinyl)urea #
NCGC00094854-01
NCGC00094854-02
NCGC00094854-03
NCGC00094854-04
NCGC00094854-05
NCGC00094854-06
NCGC00094854-07
NCGC00256403-01
NCGC00259636-01
AC-11040
AS-13865
NCI60_041675
Sodium Methanethiolate (~20% in Water)
Urea, n-(2,5-dioxo-4-imidazolidinil)-
N-(2,5-Dioxo-4(1h)-imidazolidinyl)urea
SBI-0051759.P002
A0211
AB00052307
FT-0604592
EN300-21043
C01551
D85069
Urea, (2,5-dioxo-4-imidazolidinyl)- (9CI)
AB00052307_11
3-Hydroxy-2-propyl-4-pentenoic Acid Ethyl Ester
Q409804
Urea, (2,5-dioxo-4-imidazolidinyl)-, (.+.)-
J-522839
SR-01000766252-2
SR-01000766252-3
SR-01000766252-4
W-100104
Z104486690
Allantoin, European Pharmacopoeia (EP) Reference Standard
A999F0D6-0285-41D9-A6BA-B705987B663C
Allantoin, United States Pharmacopeia (USP) Reference Standard
Allantoin, Pharmaceutical Secondary Standard; Certified Reference Material
5-Ureidohydantoin; Glyoxyldiureide; Glyoxylic diureide; Cordianine; Glyoxyldiureid; (2,5-Dioxo-4-imidazolidinyl)urea




ALLANTOIN COSMETIC GRADE
DESCRIPTION:
Allantoin Cosmetic Grade is a moisturizing and healing agent that has the ability to shed dead skin cells and leave the skin fresh and glowy.
Allantoin Cosmetic Grade is used in a variety of cosmetic and personal care products because of its many benefits.
Allantoin Cosmetic Grade is one of the latest trending ingredients that can be found in shampoos, scar creams, acne products and lotions.


CAS Number, 97-59-6
Chem/IUPAC Name:, Urea, (2,5-dioxo-4-imidazolidinyl)-
EINECS/ELINCS No:, 202-592-8
COSING REF No:, 31411


SYNONYMS OF ALLANTOIN COSMETIC GRADE:
5-ureidohydantoin, glyoxyl-diureide, 2,5-dioxo-4-imidazolidinyl-urea.



Allantoin Cosmetic Grade is a versatile ingredient used to improve the appearance and feel of the skin.
Allantoin Cosmetic Grade is a natural derivative of the comfrey plant highly effective at exfoliating dead skin cells, increasing skin hydration and softness, and causing calming and soothing effects.


Allantoin Cosmetic Grade improves the skin's moisture retention providing a smoothening effect.
Allantoin Cosmetic Grade is used in cosmetic products as an ideal addition to anti-aging products to help to minimize the appearance aging and skin damage.
In addition to its moisturizing properties, Allantoin Cosmetic Grade is an effective anti-irritant, protecting the skin.

Due to this multifunctionality Allantoin Cosmetic Grade is broadly used in a wide range of beauty care application, including skin care, toiletries, and sun and hair care products.
Allantoin Cosmetic Grade is a white to off-white, practically odorless crystalline powder.



Allantoin Cosmetic Grade occurs naturally in the roots & leaves of the comfrey plant, but to satisfy market needs allantoin is produced synthetically but nature identical.


Allantoin Cosmetic Grade improves skin irritation and hydration levels while also reducing the impacts of aging on the skin.
The chemical formula of Allantoin Cosmetic Grade is C4H6N4O3.

Allantoin Cosmetic Grade is a skin active ingredient with keratolytic, moisturizing, soothing, anti-irritant properties, promotes the renewal of epidermal cell and accelerates wounds healing.
Allantoin Cosmetic Grade is safe and non-irritant, highly compatible with the skin and with cosmetic raw materials.

Allantoin Cosmetic Grade enjoys a long history of use in cosmetics and topical pharmaceuticals with no findings of toxicity or adverse reactions.
Comply with CTFA and JSCI requirements.


USES OF ALLANTOIN COSMETIC GRADE:
Allantoin Cosmetic Grade is one of those magical cosmetic and personal care ingredients that isn't hyped enough in the world of overhyped ingredients.
Allantoin Cosmetic Grade serves many purposes such as moisturization and healing of scars and is added to a variety of products such as lotions, mascaras and shampoos.

Skin care:
Allantoin Cosmetic Grade is great for the skin as it helps in moisturizing and healing damaged surfaces.
Allantoin Cosmetic Grade also reduces skin irritation and inflammation.
Further, Allantoin Cosmetic Grade is helpful in treating scars.
Allantoin Cosmetic Grade makes the cosmetic products more hydrating and better textured.
Allantoin Cosmetic Grade is also an anti-aging ingredient that is a rage among Korean cosmetics.
Allantoin Cosmetic Grade helps reduce the appearance of fine lines and wrinkles.

Hair care:
Allantoin Cosmetic Grade is added to hair care products as it is beneficial in treating itchy and dry scalp by providing deep nourishment.
Allantoin Cosmetic Grade can soothe the scalp and make it feel refreshed.


Allantoin Cosmetic Grade has been used in a wide variety of personal care products and cosmetics for decades due to its gentleness and effectiveness including:
Skincare use for:
• Creams, lotions and cleansers for the face, hands and body
• Lip balms
• Shave and Aftershave products
• Serums, toners and masks
• Sunscreens
Bath and shower products
Makeup and cosmetics
Haircare
Infant products



ORIGIN OF ALLANTOIN COSMETIC GRADE:
Allantoin Cosmetic Grade is a naturally occurring ingredient that appears as a white powder in its raw form.
Allantoin Cosmetic Grade is derived from plants like chestnut, bearberry, and comfrey.
However, Allantoin Cosmetic Grade can also be made from urea and glyoxylic acid.
Lastly, Allantoin Cosmetic Grade can be synthetically made as well.


Allantoin Cosmetic Grade is a metabolic intermediate of a wide variety of organisms: from bacteria, to vegetals and animals.
Allantoin Cosmetic Grade was found in many plants, and particularly in the leaves and roots of comfrey (Symphytum officinale), an herb of family Boraginacee.
The roots and leaves of this herb contain from 0.6 to 1% Allantoin Cosmetic Grade and have a long history of use in the treatment of wounds in form of poultices and decoctions.

Allantoin Cosmetic Grade is the end product of purine degradation in Mammalians (except Primates) and derives from the oxidation of uric acid.
Allantoin Cosmetic Grade can’t be extracted from animals with industrial advantages, thus all internet alerts on the animal origin of Allantoin are completely unsubstantiated.
Allantoin Cosmetic Grade CTFA manufactured by Akema is the natural-identical compound fully obtained via a chemical process that make no use of substances of animal origin.


PROPERTIES AND STABILITY OF ALLANTOIN COSMETIC GRADE:
Allantoin Cosmetic Grade is a heterocyclic compound derived from purine.
Allantoin Cosmetic Grade is an odourless white powder, soluble in water to 0.5%, very slightly soluble in alcohols, insoluble in oils and apolar solvents.
Allantoin Cosmetic Grade is stable in the pH range 3-8 and to 80°C prolonged heating.
Allantoin Cosmetic Grade is fully compatible with cosmetic ingredients and with anionic, non-ionic, cationic systems.

BENEFITS OF ALLANTOIN COSMETIC GRADE:
Allantoin Cosmetic Grade has USP grade
Allantoin Cosmetic Grade Soothes and alleviates skin-irritations
Allantoin Cosmetic Grade Has moisturizing and hydrating effects

Allantoin Cosmetic Grade Recognized as skin protectant by the FDA (see below for making proper claims)
Allantoin Cosmetic Grade is Often used to minimize pore size
Allantoin Cosmetic Grade Has anti-aging properties making the skin look younger and rejuvenated


APPLICATIONS OF ALLANTOIN COSMETIC GRADE:
Allantoin Cosmetic Grade is used in Lotions, creams, sun care & after sun products, shampoos, scalp rinses, shower gels, lip & baby care products.

Allantoin Cosmetic Grade is a cosmetic ingredient that helps to hydrate the skin.
Allantoin Cosmetic Grade is a very multifunctional ingredient moisturizing and hydrating effect.
Allantoin's soothing properties are especially beneficial for dry skin, Cosmetic Grade Allantoin Cosmetic Grade helps to improve the overall texture of the skin.

USP Grade Allantoin Cosmetic Grade supports a mild exfoliating effect on the skin by promoting the elimination of old skin cells.
Allantoin Cosmetic Grade is used as a moisturizer to prevent dry skin.

Allantoin Cosmetic Grade is suitable for any personal care application.
Its use notably increases the performance of every cosmetic preparation: used at low levels on intact skin gives a smooth and healthy appearance; used on irritated, chapped and cracked skin provide relief from pain and promote healing. Allantoin is also useful as only active ingredient.

The many cosmetic applications include:
Body and face care: tonics, gels, creams, lotions, wipes.
Hand-care: gels, lotions, creams.
Shaving-care: shaving soaps, aftershaves, gels, lotions, creams.
Baby-care: diaper rash, bath products, gels, lotions, creams, powders, wipes.
Lips-care: sticks, creams.
Sun-care: sunscreens, aftersuns, suntans, gels, lotions, creams.
Hair products: shampoos, tonics.
Bath products: shower gels, bubble baths, intimate, powders, wipes.
Oral preparations: toothpastes, mouthwashes.


HOW ALLANTOIN COSMETIC GRADE WORKS
Allantoin Cosmetic Grade is a crystallized oxidation product of uric acid found naturally in many plants.
Allantoin Cosmetic Grade enhances the efficacy and appeal of dermatological and cosmetic formulations by acting as a skin protectant and providing necessary hydration.
The addition of Allantoin Cosmetic Grade to cosmetic formulations results in softer, suppler skin.

In addition to moisturizing, Allantoin Cosmetic Grade also helps to gently exfoliate the skin by softening the top layer of skin.
Because of its soothing properties as a keratolytic agent, Allantoin Cosmetic Grade can be a great ingredient in formulations developed to reduce dullness or for sensitive, acne-prone skin.

Since Allantoin Cosmetic Grade is both a skin protectant and moisturizer, it helps protect against trans-epidermal water loss.
Preventing moisture loss is important for calming irritated skin and improving skin texture for all skin types.






CHEMICAL AND PHYSICAL PROPERTIES OF ALLANTOIN COSMETIC GRADE:
Boiling Point, 478°C
Melting Point, 230°C
pH, 3.0-8.0
Solubility, Soluble in water
Purity 99-100%. Melting point 230°C (446°F).
Item Form, Powder
Material Type Free, Odorless
Product Benefits, Anti-aging,Hydrating,Moisturizing,Soothing
Recommended Uses For Product, Hydrating,Moisturizing,Anti-aging
Characteristic, White crystalline powder
Odor, Characteristically mild
Identification, Meets The Requirements
Angular Rotation, -0.10º~+0.10º
Acidity Or Alkalinity, Conform
Loss On Drying, ≤0.1%
Residue On Ignition, ≤0.1%
Reducing Substances, Complies
Related Compounds, ≤0.5%
Assay, 98.5 ~ 101.0%
Standard, USP32
Product Name, Allantoin
Synonyms, N-(2,5-dioxo-4-imidazolinidinyl)urea,allantoin
CAS, 97-59-6
Molecular formula, C4H6N4O3
Molecular Weight, 158.115
Physical and Chemical Properties, P.:230 °C (dec.)(lit.)
P.:478ºC
P.:230-234°C
Density:1.7±0.1 g/cm3
General Description, White Powder
Packing, 25kg/Drum
Storage condition, Stored in the dry and ventilated inside storeroom, prevent direct sunlight, slightly pile and put down
Specifications,
Appearance, White Powder
Odor, Orderless
Fineness, >500 Mesh
Assay %, 98.50-101.00%
PH(0.5%aq), 4.00-6.00
Nitroren%, 35.00-35.50
M.P ºC, >225
Heavy metals mg/kg, 10min
Loss on drying %, <0.20
Ash %, <0.10
Optical rotation, -0.1° - +0.1°
Product Name, Allantoin
Odor, Characteristically mild
Appearance, White crystalline powder
Assay , 98.5%-101.0%
Identification, Infrared spectrum is march with the spectrum of allantoin CRSThin-Layer ChromatographicConform
Acidity or alkalinity, Conform
Angular rotation, -0.10º~+0.10º
Loss on drying %, 0.1 max
Residue on ignition %, 0.1 max
M.P ºC, 226-240
Heavy metals( pb) %, <0.001
Ph value, 4.5-6.5
Related substances %, 0.5 max



SAFETY INFORMATION ABOUT ALLANTOIN COSMETIC GRADE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product


ALLANTOINE
Allantoine is a chemical compound with formula C4H6N4O3.
Allantoine is also called 5-ureidohydantoin or glyoxyldiureide.
Allantoine is a diureide of glyoxylic acid.
Allantoine is a major metabolic intermediate in most organisms including animals, plants and bacteria.


CAS Number: 97-59-6
EC Number: 202-592-8
MDL number: MFCD00005260
Chemical formula: C4H6N4O3


Allantoine is produced from uric acid, which itself is a degradation product of nucleic acids, by action of urate oxidase (uricase).
The occurs as a natural mineral compound (IMA symbol Aan).
Allantoine is a moisturizing and healing agent that has the ability to shed dead skin cells and leave the skin fresh and glowy.


The chemical formula of Allantoine is C4H6N4O3.
Allantoine is one of those magical cosmetic and personal care ingredients that isn't hyped enough in the world of overhyped ingredients.
Allantoine serves many purposes such as moisturization and healing of scars and is added to a variety of products such as lotions, mascaras and shampoos.


Allantoine is a naturally occurring ingredient that appears as a white powder in its raw form.
Allantoine is derived from plants like chestnut, bearberry, and comfrey.
However, Allantoine can also be made from urea and glyoxylic acid.


Lastly, Allantoine can be synthetically made as well.
Allantoine is renowned for its softening and soothing properties.
Allantoine is an ingredient of choice for your "homemade" repairing treatments and your preparations for sensitive or blemished skin.


Allantoine, as I-1R agonist, has the potential to develop as a new therapeutic agent for hypertension.
Allantoine has memory-enhancing, anti-oxidative and anti-inflammatory activities; it can enhance the antifungal activity of Nanoencapsulation.
Allantoine is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth.


Allantoine mediates PI3K-Akt-GSK-3β signal pathway.
Allantoine is a chemical compound with formula C4H6N4O3.
Allantoine is also called 5-ureidohydantoin or glyoxyldiureide.


Allantoine is a diureide of glyoxylic acid.
Named after the allantois, an amniote embryonic excretory organ in which Allantoine concentrates during development in most mammals except humans and higher apes, it is a product of oxidation of uric acid by purine catabolism.


After birth, Allantoine is the predominant means by which nitrogenous waste is excreted in the urine of these animals.
In humans and higher apes, the metabolic pathway for conversion of uric acid to Allantoine is not present, so the former is excreted.
Recombinant rasburicase is sometimes used as a drug to catalyze this metabolic conversion in patients.


In fish, Allantoine is broken down further (into ammonia) before excretion.
Allantoine is a major metabolic intermediate in many other organisms including plants and bacteria.
Allantoine, in its organic form, is a compound that is found and extracted from certain plants like sugar beets, chamomile and wheat sprouts.


It’s also known as aluminum dihydroxy allantoinate, but we’ll just call it Allantoine to keep things simple.
Most notably, Allantoine can be extracted from the comfrey plant, which is native to parts of Asia and Europe.
In skincare, Allantoine that is mainly used is recreated in labs to be chemically equivalent to its natural form.


This lab-created version, such as allantoin glycyrrhetinic acid, mimics the effects of natural Allantoine and has been proven to be safe enough to work in many different beauty products.
Allantoine’s core function is to be a non-toxic moisturising agent, so it’s a great ingredient to look out for if you’re in need of deep hydration or anti-ageing.


Allantoine’s a mild keratolytic, which means that it has the ability to increase the water content within cells and also helps to shed the outer layers of skin (desquamation).
Along with these major factors, Allantoine also has tons of other bonuses!


Allantoine is one of the main active principles of comfrey roots (regenerative and very healing plant).
Allantoine is a hygroscopic white powder.
Allantoine is stored away from moisture.


The cosmetics industry extracts Allantoine from the mucus of certain gastropods.
In plants, Allantoine is found in the roots of comfrey and in cereal seeds.
Recognized for its moisturizing, anti-irritant properties and its cellular trophic action (beneficial on cell growth), Allantoine is very effective even at low concentration (from 0.1%).


While Allantoine is present in botanical extracts from comfrey, it is usually synthesized chemically to meet global demand. Allantoine is a synthesized nature-identical product manufactured to USP specifications.
Allantoine is non-toxic, non-irritant and non-allergenic.


Allantoine is an ingredient for your restorative, soothing and anti-inflammatory preparations.
Allantoine is a powerful ingredient, which makes it a must-have for sensitive, damaged or irritated skin.
Allantoine can be of organic or plant origin, it is found in one of the active ingredients of comfrey, roots of a plant known as "donkey's ears", but also in cereal seeds.


Allantoine is used anti-wrinkle, regenerate new tissues, an antioxidant that fights free radicals that destroy skin and accelerate the ageing process.
Allantoine is used dissolve in water.
Allantoine is made from glycolic acid and urea.


The white odourless powder, Allantoine, is well soluble in water and not sensitive to heat.
Allantoine comes in the form of a white crystalline powder.
Allantoine is a nitrogenous compound that is found both in the plant environment (Comfrey root for example) or animal (in the urine of calves).


Allantoine can also be obtained synthetically from uric acid.
Allantoine is a moisturizing agent, almost as effective as urea in binding moisture.
Originally Allantoine is a plant metabolite, but today it is also made synthetically.


Ideal in care for oily or impure skin, Allantoine eliminates dead skin cells and excessive sebum.
Allantoine also has a healing, smoothing and regenerating action on skin cells.
Allantoine is an ideal cosmetic active ingredient to help regenerate and heal the skin.


Allantoine softens and soothes the skin.
Allantoine is useful for the preparation of moisturizing and soothing cosmetics.
Allantoine is an active substance present in, among other things, Comfrey (Symphytum officinale) and Horse chestnut (Aesculus hippocastanum).


Allantoine has a wound healing and skin regenerating effect.
Allantoine makes the skin smoother and softer by removing dead skin cells.
The skin can therefore also be better hydrated and the production of new skin cells is stimulated.


Allantoine is made biotechnologically from urea and glycolic acid.
Allantoine is suitable for all skin types, including sensitive (baby) skin.



USES and APPLICATIONS of ALLANTOINE:
Allantoine is used in a variety of cosmetic and personal care products because of its many benefits.
Allantoine is one of the latest trending ingredients that can be found in shampoos, scar creams, acne products and lotions.
Allantoine improves skin irritation and hydration levels while also reducing the impacts of ageing on the skin.


Allantoine has healing, soothing and regenerating properties for the skin, it tightens the pores, so it will be widely used in the event of wounds or burns.
Allantoine regulates the secretion of sebum,
Allantoine has a very gentle keratolytic action, it eliminates dead cells and stimulates cell regeneration.


Allantoine is also a moisturizing and softening ingredient, removes lesions, irritations and roughness of the skin.
Allantoine is a cosmetic active ingredient known for its regenerating and healing properties.
Moisturizing, Allantoine maintains the cutaneous hydrolipidic film and makes the skin supple and soft.


Also soothing and anti-inflammatory, Allantoine is ideal for fighting skin irritations.
For whom: Allantoine is used all skin types, especially sensitive, damaged, irritated skin, skin damaged by the sun, oily skin and prone to imperfections.
For what: Allantoine is used cream, balm, repairing milk or after-sun, shaving balm for men, face care for irritated skin.


Allantoine is frequently used in the treatment of wounds, burns and skin ulcers.
Allantoine helps in the regeneration of damaged tissues and acts as a healing accelerator.
Allantoine's many benefits make its use very beneficial for after-shave balms, for sensitive skin or for babies and children.


Allantoine has a moisturizing and keratolytic effect, increasing the water content of the extracellular matrix and improving the desquamation of the upper layers of dead skin cells, increasing the smoothness of the skin; promote cell proliferation and wound healing; and a soothing, anti-irritant and protective effect on the skin by forming complexes with irritating and sensitizing agents.


Free-flowing synthetic hygroscopic powder, Allantoine, widely used in cosmetic, dermatological and pharmaceutical formulations for its soothing and anti-irritant properties.
Allantoine stimulates the formation of healthy, normal tissue, even at low concentrations.


Allantoine is used in cosmetic formulation in body care, after shave lotion, antiperspirants.
The hand cream with Allantoine intensively repairs damaged hands.
Allantoine is used regularly, it's Repairing Hand Cream soothes and repairs damaged hands and restores their suppleness and softness


Allantoine is the star ingredient for promoting healthy skin.
Thanks to its restorative, soothing and moisturizing action; Allantoine stimulates skin renewal, regulates the inflammatory process, improves the skin's ability to retain water.
Thanks to its keratolytic effect, Allantoine helps eliminate dead cells, which regenerates the skin, restoring its radiance and softness.


Finally, thanks to its softening effect, Allantoine leaves the skin soft and supple.
Allantoine has traditionally been used to stimulate wound healing because of its stimulating effect on the production of new cells.
Allantoineis is now known for its exfoliating and keratolytic action.


Allantoine has a light exfoliating effect by removing dead skin cells and creating soft, smooth skin.
Allantoine has a keratolytic effect by softening and softening the cornea, making it better able to retain water.
Allantoine makes the skin moister, softer and more supple.


Allantoine is suitable for all skin types, including sensitive (baby) skin.
Allantoine can be used in creams and lotions especially for sensitive, dry and irritated skin.
In addition, Allantoine can be processed in acne creams and after-sun products.


In cosmetics, Allantoine is used for its astringent, anti-irritant, anti-inflammatory, healing and moisturizing properties.
Allantoine is also used in the treatment of dentin hypersensitivity.
Allantoine is traditionally used for its healing, regenerating and soothing properties.


In cosmetics, Allantoine is frequently obtained from snail slime.
Here we use a synthetic Allantoine, equivalent to natural in terms of non-toxicity and safety.
Allantoine has moisturizing and keratolytic properties.


By increasing the amount of water in the extracellular matrix and enhancing the elimination of dead cells , Allantoine softens the skin, stimulates tissue regeneration and brightens the complexion.
In addition, Allantoine reacts with irritants and sensitizers present on the skin and deactivates them.


Skin care uses of Allantoine: milk, cream, balm, treatment, lotion, gel, mask
Allantoine is also suitable as a moisturizing active ingredient in shampoos for an irritated scalp and eczema.
Allantoine is used in creams and lotions for sensitive, dry, irritated and acne-prone skin.


-Uses of Allantoine :
Skin care (irritations, sunburn, burning, dry skin, chapped lips, etc.), bath and shower products.
Allantoine promotes the cleansing of dead skin and the production of new cells.


-Skin care:
Allantoine is great for the skin as it helps in moisturizing and healing damaged surfaces.
Allantoine also reduces skin irritation and inflammation. Further, Allantoine is helpful in treating scars.
Allantoine makes cosmetic products more hydrating and better textured.
Allantoine is also an anti-ageing ingredient that is a rage among Korean cosmetics.
Allantoine helps reduce the appearance of fine lines and wrinkles.


-Hair care:
Allantoine is added to hair care products as it is beneficial in treating itchy and dry scalp by providing deep nourishment.
Allantoine can soothe the scalp and make it feel refreshed.


-Cosmetics:
Manufacturers may use Allantoine as an ingredient in over-the-counter cosmetics.


-Pharmaceuticals:
Allantoine is frequently present in toothpaste, mouthwash, and other oral hygiene products, in shampoos, lipsticks, anti-acne products, sun care products, and clarifying lotions, various cosmetic lotions and creams, and other cosmetic and pharmaceutical products.


-Biomarker of oxidative stress:
Since uric acid is the end product of the purine metabolism in humans, only non-enzymatic processes with reactive oxygen species will give rise to Allantoine, which is thus a suitable biomarker to measure oxidative stress in chronic illnesses and senescence.


-Applications of Allantoine:
*Face and body creams and lotions
*lip balms
*shaving care
*toothpastes
*lipstick
*anti-acne care (regulates sebum)
*sun creams and after sun care
*Deodorant
*baby care
*hand and foot creams



MAIN FUNCTIONS OF ALLANTOINE:
*Restorative
*Soothing
*Keratolytic



FUNCTIONS OF ALLANTOINE:
*Skin conditioning agent:
Allantoine keeps the skin in good condition
*Skin protection agent:
Allantoine helps to avoid the harmful effects of external factors on the skin
*Soothing Agent:
Allantoine helps alleviate skin or scalp discomfort
Allantoine is present in 6.12% of cosmetics.



PROPERTIES OF ALLANTOINE:
*Hydrates and naturally produces keratin.
*Repairs the skin, helps it heal and makes it softer.
*Anti-inflammatory & soothing:
Allantoine significantly reduces all feelings of irritation and discomfort (acne type, burns, itching, sunburn, chapping, aftershave).
*Healing:
Powerful repairer, Allantoine promotes the renewal of epidermal cells and accelerates the healing of wounds.
*Moisturizing:
Allantoine increases water content while maintaining skin hydration, making it smoother and suppler.
*Keratolytic:
Allantoine effectively helps eliminate dead skin cells to restore its softness.



ALLANTOINE CAN BE USED AS AN INGREDIENT IN PREPARATIONS:
*Soothing and restorative treatments
*After-sun care
*Hand and foot care
*Post-depilation or after-shave cream or gel
*Cleansing products for sensitive skin (soaps, shower gels, make-up remover lotions, etc.)
*Sensitive skin deodorant



WHAT DOES ALLANTOINE DO IN A FORMULATION?
*Moisturising
*Refreshing
*Soothing



WHAT ARE THE BENEFITS OF ALLANTOINE?
As mentioned, Allantoine’s an amazing ingredient for moisturising the skin and making sure that hydration is retained.
As a keratolytic, Allantoine’s also a light exfoliant that removes dead skin and helps to smooth out the texture of your skin.
In turn, this exfoliation process also helps to brighten and even out the skin tone.
On top of this, Allantoine’s also got soothing and wound-healing properties as well!

If you’re after a multi-purpose all-rounder, I’ll say that Allantoine is a strong candidate!
However, as it has exfoliating properties, Allantoine should be avoided for everyday use in high amounts.
Allantoine should also be used in precaution with other exfoliating ingredients in order to avoid irritation and sensitivity caused by over-exfoliation.



PROPERTIES OF ALLANTOINE:
*Healing and sebum regulator
*Hydrating and soothing
*Restorative and regenerating



SAFETY PROFILE OF ALLANTOINE:
Allantoine is safe for skin and hair and has no known risks or side effects.
Allantoine is a natural ingredient that is non-comedogenic and does not cause acne or breakouts.
Allantoine suits all the skin types and is also quite beneficial for sensitive skin.
Further, limited data has shown no risks when used during pregnancy.
Allantoine can or cannot be vegan depending on its source of derivation.



HISTORY OF ALLANTOINE:
Allantoine was first isolated in 1800 by the Italian physician Michele Francesco Buniva (1761–1834) and the French chemist Louis Nicolas Vauquelin, who mistakenly believed it to be present in the amniotic fluid.
In 1821, the French chemist Jean Louis Lassaigne found it in the fluid of the allantois; he called it "l'acide allantoique".
In 1837, the German chemists Friedrich Wöhler and Justus Liebig synthesized it from uric acid and renamed it "allantoïn".
Allantoine has been shown to improve insulin resistance when administered to rats and to increase lifespan when administered to the nematode worm Caenorhabditis elegans.



BACTERIA:
In bacteria, purines and their derivatives (such as allantoin) are used as secondary sources of nitrogen under nutrient-limiting conditions.
Their degradation yields ammonia, which can then be utilized.
For instance, Bacillus subtilis is able to utilize Allantoine as its sole nitrogen source.
Mutants in the B. subtilis pucI gene were unable to grow on allantoin, indicating that it encodes an Allantoine transporter.

In Streptomyces coelicolor, allantoinase (EC 3.5.2.5) and allantoicase (EC 3.5.3.4) are essential for Allantoine metabolism.
In this species the catabolism of Allantoine, and the subsequent release of ammonium, inhibits antibiotic production (Streptomyces species synthesize about half of all known antibiotics of microbial origin).

Allantoine is present in botanical extracts of the comfrey plant and in the urine of most mammals.
Chemically synthesized bulk Allantoine, which is chemically equivalent to natural allantoin, is safe, non-toxic, compatible with cosmetic raw materials and meets CTFA and JSCI requirements.
Over 10,000 patents reference Allantoine.



PROPERTIES OF ALLANTOINE:
As a cosmetic ingredient, the cosmetic active ingredient Allantoine is recognized for these properties:
*Restorative:
Allantoine stimulates skin renewal
*Soothing:
Allantoine regulates the inflammatory process
Allantoine maintains good skin hydration:
Allantoine improves the skin's ability to retain water
*Keratolytic:
Allantoine helps eliminate dead cells, which regenerates the skin, restoring its radiance and softness
*Softening:
Allantoine makes the skin softer and more supple



ALLANTOIN, FOR WHICH COSMETIC RECIPES?
*Cosmetic active ingredient for face care
*Ingredients for homemade cosmetic recipe for the body *Recipe for homemade cosmetics for the hands
*Balms, creams and after-sun milks
*Aftershave balms for men
*Soothing care after waxing, shaving
*Cream for damaged feet and hands
*Repairing facial care for sensitive skin
*Protective barrier cream



ALLANTOINE FOR THE BODY:
Allantoine is used in after-sun care, allantoin will promote cell regeneration.
Allantoine also fights effectively against irritation and mild sunburn.



ALLANTOINE FOR THE FACE:
Allantoine is hydrating, softening, soothing and regenerating.
Incorporated into your facial care, this active ingredient will protect your skin from external aggressions and repair irritations.



THE PROPERTIES OF ALLANTOINE:
In the cosmetics industry, Allantoine is recognized for its properties:
*Repairing: Allantoine stimulates the renewal of the skin
*Soothing: Allantoine regulates the inflammatory process and reduces redness
*Moisturizing: Allantoine improves the skin's ability to retain water
*Keratolytics: Allantoine helps eliminate dead cells, which regenerates the skin, restores radiance and softness
*Softening: Allantoine makes the skin softer and more supple



DIRECTIONS OF ALLANTOIN:
*Sensitive skins
*Skin prone to discomfort (after-shave, after-sun, etc.)
*Delicate skins
*Skin with imperfections
Allantoine enters into the composition of skin care: soaps, shower gels, hand and foot care, and deodorant.
Allantoine active and known for its softening and soothing properties.
Allantoine is an ingredient of choice for your "homemade" repairing care and your preparations for sensitive skin or skin with imperfections.
*Stimulates skin renewal
*Regulates the inflammatory process
*Maintains good skin hydration
*Improves the skin's ability to retain water
*Helps remove dead cells
*Makes the skin softer and more supple



PHYSICAL and CHEMICAL PROPERTIES of ALLANTOINE:
Chemical formula: C4H6N4O3
Molar mass: 158.117 g·mol−1
Appearance: colourless crystalline powder
Odor: odorless
Density: 1.45 g/cm3
Melting point: 230 °C (446 °F; 503 K)
Boiling point: 478 °C (892 °F; 751 K)
Solubility in water: 0.57 g/100 mL (25 °C), 4.0 g/100 mL (75 °C)
Solubility: soluble in alcohol, pyridine, NaOH, insoluble in ethyl ether
log P: −3.14
Acidity (pKa): 8.48
Boiling Point: 478°C
Melting Point: 230°C
pH: 3.0-8.0
Solubility: Soluble in water

Physical state: solid
Color: white
Odor: No data available
Melting point/freezing point:
Melting point/range: 230 °C - dec.
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available



FIRST AID MEASURES of ALLANTOINE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ALLANTOINE:
-Personal precautions, protective equipment and emergency procedures:
Advice for non-emergency personnel:
Evacuate the danger area, observe emergency procedures, consult an expert.
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ALLANTOINE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ALLANTOINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ALLANTOINE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of ALLANTOINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available
-Incompatible material:
no information available



SYNONYMS:
NSC 7606
5-Ureidohydantoin
Glyoxylic(acid) diureide


ALLOMALEIC ACID
Allomaleic acid has a role as a food acidity regulator, a fundamental metabolite and a geroprotector.
Allomaleic acid is the trans isomer of butenedioic acid, while maleic acid is the cis isomer.
Allomaleic acid is a butenedioic acid in which the C=C double bond has E geometry.

CAS Number: 110-17-8
EC Number: 203-743-0
Chemical Formula: HOOCCHCHCOOH
Molar Mass: 116.07 g/mol

Allomaleic acid is an organic compound with the formula HO2CCH=CHCO2H.
A white solid, Allomaleic acid occurs widely in nature.

Allomaleic acid has a fruit-like taste and has been used as a food additive.
Allomaleic acid E number is E297.

The salts and esters are known as fumarates.
Fumarate can also refer to the C4H2O2−4 ion (in solution).
Allomaleic acid is the trans isomer of butenedioic acid, while maleic acid is the cis isomer.

Allomaleic acid can be prepared by fermentation by employing Rhizopus species.
Recently, industrial-scale synthesis of Allomaleic acid from renewable feedstocks and lignocellulosic biomass has been proposed

Allomaleic acid is an organic compound (this means Allomaleic acid consists of carbon).
The chemical formula of Allomaleic acid is C4H4O4.

Allomaleic acid is mostly found in Allomaleic acid solid state and is white in color.
Allomaleic acid has a fruit-like taste.

Allomaleic acid is also known as Fumaric acid.
Allomaleic acid is a dicarboxylic acid.

Allomaleic acid is widely used as a food additive.
Even the human skin produces Allomaleic acid when Allomaleic acid is exposed to sunlight.

Allomaleic acid is a by-product of the urea cycle in human beings.
The salts and esters of Allomaleic acid are collectively known as fumarates.
Fumaric and maleic acids were discovered by Braconnet and by Vauquelin separately while they were performing the dry distillation of malic acid in the year 1817.

Allomaleic acid appears as a colorless crystalline solid.
The primary hazard is the threat to the environment.

Immediate steps should be taken to limit spread to the environment.
Combustible, though may be difficult to ignite.
Allomaleic acid is used to make paints and plastics, in food processing and preservation, and for other uses.

Allomaleic acid is a butenedioic acid in which the C=C double bond has E geometry.
Allomaleic acid is an intermediate metabolite in the citric acid cycle.

Allomaleic acid has a role as a food acidity regulator, a fundamental metabolite and a geroprotector.
Allomaleic acid is a conjugate acid of a fumarate(1-).

Allomaleic acid is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Allomaleic acid is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Allomaleic acid or trans-butenedioic acid, is a white crystalline chemical compound widely found in nature.
Allomaleic acid is a key intermediate in the tricarboxylic acid cycle for organic acid biosynthesis in humans and other mammals.
Allomaleic acid is also an essential ingredient in plant life.

When used as a food additive, the hydrophobic nature of Allomaleic acid results in persistent, long lasting sourness and flavor impact.
The versatile compound also decreases the pH with minimal added sourness in products with pHs greater than 4.5.
Allomaleic acid low molecular weight gives Allomaleic acid more buffering capacity than other food acids at pHs near 3.O.

Because of Allomaleic acid strength, less Allomaleic acid is required when compared to other organic food acids, therefore reducing costs per unit weight.

Allomaleic acid (C4H4O4) is an organic acid widely found in nature, and is a component of organic biosynthesis is humans.
Chemically, Allomaleic acid is an unsaturated dicarboxylic acid.

Allomaleic acid exists as white or nearly white crystals, odorless with a very tart taste.
Allomaleic acid is generally nontoxic and nonirritant.

Allomaleic acid has been used in food and beverage products since the 1940s.
Food research shows that Allomaleic acid can improve quality and reduce the costs of many food and beverage products.

Allomaleic acid is non-hygroscopic (absorbs no moisture).
In the cosmetic industry, Allomaleic acid is used as a bath salt cleaning agent for dentures.

Allomaleic acid also is used in animal feeds.
Allomaleic acid is used in oral pharmaceutical formulations and has been used clinically in the treatment of psoriasis.
Dimethyl fumarate (Tecfidera) is the methyl ester of Allomaleic acid, and was approved in 2013 for use in multiple sclerosis.

Allomaleic acid is obtained from the transformation of maleic anhydride or maleic acid solutions resulting from the isomerization process (washing) of phthalic anhydride.
Allomaleic acid application areas are unsaturated polyester resins, the acidifying animal feed and plasticized products.

Allomaleic acid is an important specialty chemical with wide industrial applications ranging from Allomaleic acid use as feedstock for the synthesis of polymeric resins to acidulant in foods and pharmaceuticals.
Currently, Allomaleic acid is mainly produced by petroleum-based chemical synthesis.
Limited petroleum resources, rising oil prices, and heightened environmental concern of chemical synthesis have prompted interest in the development of bio-based Allomaleic acid from renewable resources.

Filamentous fungal fermentation with Rhizopus spp can produce Allomaleic acid from glucose via a reductive tricarboxylic acid (TCA) pathway and was once used in the industry before the rising of the petrochemical industry.
However, conventional Allomaleic acid fermentation is expensive because of Allomaleic acid low product yield and productivity.

Filamentous fungal fermentation is also difficult to operate because of Allomaleic acid morphology.
Methods to control cell growth in the pellet form and to immobilize the mycelia in biofilm have been developed to improve fermentation performance.

Allomaleic acid attenuates the eotaxin-1 expression in TNF-α-stimulated fibroblasts by suppressing p38 MAPK-dependent NF-Κb signaling.
Allomaleic acid has recently been identified as an oncometabolite or an endogenous, cancer-causing metabolite.

High levels of this organic acid can be found in tumors or biofluids surrounding tumors.
Allomaleic acid oncogenic action appears due to Allomaleic acid ability to inhibit prolyl Hydroxylase-containing enzymes.

Allomaleic acid (Fumarate, 2-Butenedioic acid, Trans-Butenedioic acid) is an intermediate in the citric acid cycle used by cells to produce energy in the form of adenosine triphosphate (ATP) from food; also a product of the urea cycle.

Allomaleic acid is an organic compound with the formula (COOH)CH=CH(COOH).
A white solid, Allomaleic acid occurs widely in nature.

Allomaleic acid has a fruit-like taste and has been used as a food additive.
Allomaleic acid E number is E297.

Allomaleic acid is the trans isomer of butenedioic acid, while maleic acid is the cis isomer.

Allomaleic acid is produced naturally in eukaryotic organisms from succinate in complex 2 of the electron transport chain via the enzyme succinate dehydrogenase, which is involved in ATP production.
The food grade product can be obtained by chemical synthesis or by biosynthesis.
Allomaleic acid is used for controlling malolactic fermentation in wines under conditions stipulated by regulation.

Production by chemical synthesis is the most common:
Allomaleic acid involves the isomerisation of maleic acid obtained from the hydrolysis of maleic anhydride, produced from the oxidation of butane or benzene. Production by biosynthesis, which is more sustainable, should develop rapidly.
Allomaleic acid involves the fermentation by Rhizopus oryzae, in particular, of agri-food residues (e.g. from apples).

The Allomaleic acid is prepared in solution in a volume of wine before incorporation.

Applications of Allomaleic acid:
Allomaleic acid has been used as a standard for the quantitative determination of phenolic compounds in nettle samples by HPLC.
Allomaleic acid may be used in the preparation of L-Lysine-Allomaleic acid crystals.
Allomaleic acid may also be employed for the industrial manufacture of synthetic resins and eco-friendly/biodegradable polymers.

When used in wine, Allomaleic acid enables you to control malolactic fermentation.
In fact, when added at an early stage after the end of alcoholic fermentation (fructose/glucose under 1 g/L), Allomaleic acid blocks all malolactic fermentation.

Added during malolactic fermentation, Allomaleic acid allows the fermentation to be partially completed.
Allomaleic acid is a tool of great interest when you wish to limit [the use of SO2] or make wines without SO2.

Uses of Allomaleic acid:
The esters of Allomaleic acid are used for the treatment of psoriasis due to the antioxidants and anti-inflammation properties.
Allomaleic acid is used as a food additive.

Allomaleic acid helps preserve the taste and quality of the food products due to the low water absorption capacity of the Allomaleic acid.
Allomaleic acid is used by pharmacies to produce ferrous fumarate and alexipharmic.
Allomaleic acid is used in the production of Tartaric acid.

Allomaleic acid is related to malic acid, and, like malic acid, Allomaleic acid is involved in the production of energy (in the form of adenosine triphosphate [ATP]) from food.

Allomaleic acid is an essential biochemical in the cellular respiration of plants and animals.
Allomaleic acid is used as a fortifier (paper size resins, unsaturated polyester resins, and alkyd surface coating resins), food antioxidant, dye mordant, and medication.

Allomaleic acid is also used in dentifrices (stain remover) and to make other chemicals.
Allomaleic acid is used in rosin esters and adducts, drying oils, printing inks, and foods (acidulant and flavoring agent).

Allomaleic acid is used primarily in liquid pharmaceutical preparations as an acidulant and flavoring agent.
Allomaleic acid may be included as the acid part of effervescent tablet formulations, although this use is limited as Allomaleic acid has an extremely low solubility in water.

Allomaleic acid is also used as a chelating agent which exhibits synergism when used in combination with other true antioxidants.
In the design of novel pelletized formulations manufactured by extrusion-spheronization, Allomaleic acid was used to aid spheronization, favoring the production of fine pellets.

Allomaleic acid has also been investigated as an alternative filler to lactose in pellets.
Allomaleic acid has been investigated as a lubricant for effervescent tablets, and copolymers of Allomaleic acid and sebacic acid have been investigated as bioadhesive microspheres.

Allomaleic acid has also been used in film-coated pellet formulations as an acidifying agent and also to increase drug solubility.
Allomaleic acid is also used as a food additive at concentrations up to 3600 ppm, and as a therapeutic agent in the treatment of psoriasis and other skin disorders.

Allomaleic acid is naturally produced by the body, however for industrial applications Allomaleic acid is synthesized chemically.
Allomaleic acid is used to impart a tart taste to processed foods.

Allomaleic acid is also used as an antifungal agent in boxed foods such as cake mixes and flours, as well as tortillas.
Allomaleic acid is also added to bread to increase the porosity of the final baked product.

Allomaleic acid is used to impart a sour taste to sourdough and rye bread.
In cake mixes, Allomaleic acid is used to maintain a low pH and prevent clumping of the flours used in the mix.

In fruit drinks, Allomaleic acid is used to maintain a low pH which, in turn, helps to stabilize flavor and color.
Allomaleic acid also prevents the growth of E. coli in beverages when used in combination with sodium benzoate.

When added to wines, Allomaleic acid helps to prevent further fermentation and yet maintain low pH and eliminate traces of metallic elements.
In this fashion, Allomaleic acid helps to stabilize the taste of wine.

Allomaleic acid can also be added to dairy products, sports drinks, jams, jellies and candies.
Allomaleic acid helps to break down bonds between gluten proteins in wheat and helps to create a more pliable dough.
Allomaleic acid is used in paper sizing, printer toner, and polyester resin for making molded walls.

Food:
Allomaleic acid has been used as a food acidulant since 1946.
Allomaleic acid is approved for use as a food additive in the EU, USA and Australia and New Zealand.

As a food additive, Allomaleic acid is used as an acidity regulator and can be denoted by the E number E297.
Allomaleic acid is generally used in beverages and baking powders for which requirements are placed on purity.

Allomaleic acid is used in the making of wheat tortillas as a food preservative and as the acid in leavening.
Allomaleic acid is generally used as a substitute for tartaric acid and occasionally in place of citric acid, at a rate of 1 g of Allomaleic acid to every ~1.5 g of citric acid, in order to add sourness, similarly to the way malic acid is used.
As well as being a component of some artificial vinegar flavors, such as "Salt and Vinegar" flavored potato chips, Allomaleic acid is also used as a coagulant in stove-top pudding mixes.

The European Commission Scientific Committee on Animal Nutrition, part of DG Health, found in 2014 that Allomaleic acid is "practically non-toxic" but high doses are probably nephrotoxic after long-term use.

Medicine:
Allomaleic acid was developed as a medicine to treat the autoimmune condition psoriasis in the 1950s in Germany as a tablet containing 3 esters, primarily dimethyl fumarate, and marketed as Fumaderm by Biogen Idec in Europe.
Biogen would later go on to develop the main ester, dimethyl fumarate, as a treatment for multiple sclerosis.

In patients with relapsing-remitting multiple sclerosis, the ester dimethyl fumarate (BG-12, Biogen) significantly reduced relapse and disability progression in a phase 3 trial.
Allomaleic acid activates the Nrf2 antioxidant response pathway, the primary cellular defense against the cytotoxic effects of oxidative stress.

Widespread uses by professional workers:
Allomaleic acid is used in the following products: laboratory chemicals, adhesives and sealants, plant protection products, inks and toners and pH regulators and water treatment products. Allomaleic acid is used in the following areas: scientific research and development, building & construction work and agriculture, forestry and fishing. Allomaleic acid is used for the manufacture of: machinery and vehicles, furniture and electrical, electronic and optical equipment. Release to the environment of Allomaleic acid can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates). Other release to the environment of Allomaleic acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Uses at industrial sites:
Allomaleic acid is used in the following products: polymers, adhesives and sealants, coating products, pharmaceuticals, inks and toners and laboratory chemicals.
Allomaleic acid has an industrial use resulting in manufacture of another substance (use of intermediates).

Allomaleic acid is used in the following areas: formulation of mixtures and/or re-packaging and scientific research and development.
Allomaleic acid is used for the manufacture of: chemicals.
Release to the environment of Allomaleic acid can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture and as processing aid.

Industry Uses:
Agricultural chemicals (non-pesticidal)
Intermediates
Monomers
Not Known or Reasonably Ascertainable
Other (specify)
Paint additives and coating additives not described by other categories
Processing aids not otherwise specified
Processing aids, specific to petroleum production
Surface active agents
Waterproofing agent

Consumer Uses:
Allomaleic acid is used in the following products: adhesives and sealants, coating products, inks and toners and cosmetics and personal care products.
Other release to the environment of Allomaleic acid is likely to occur from: outdoor use and indoor use as processing aid.

Other Consumer Uses:
Agricultural chemicals (non-pesticidal)
Flavoring and nutrient
Not Known or Reasonably Ascertainable
Other (specify)

Therapeutic Uses:
Allomaleic acid is used in oral pharmaceutical formulations and food products, and is generally regarded as a relatively nontoxic and nonirritant material.

Allomaleic acid preparations are used as long term and effective treatment of psoriasis.

Allomaleic acid and Allomaleic acid esters (FAE) are already in use for treatment of psoriasis and are known to have an immunomodulatory effect.
A phase II clinical study in relapsing-remitting multiple sclerosis (RRMS) patients with the modified Allomaleic acid ester BG-12 showed as "proof of principle" in a frequent MRI design that FAE significantly reduce the number of gadolinium-enhancing lesions after 24 weeks of treatment.
Further phase III studies have been started to explore the long-term efficacy of this substance.

Oral treatment of psoriasis on an outpatient basis, using a preparation containing Allomaleic acid derivatives, was evaluated as initial monotherapy (3 months) and as long-term basic therapy (12-14 months) in 13 and 11 patients, respectively.
The course of the disease was analysed in each individual case.

After completion of both parts of the trial, half of the patients that had only responded poorly to conventional antipsoriatic therapy showed a significant improvement which occurred after several weeks of treatment.
In 4 patients the medication had to be stopped because of abdominal pain.

No severe side effects, particularly of renal, hepatic or hematological nature, could be established.
Studies in mice and rats disclosed only a low acute toxicity of the Allomaleic acid derivatives used.

In additional analyses, hypotheses were dealt with concerning the mechanism of action of Allomaleic acid in psoriasis.
To establish Allomaleic acid derivatives in the treatment of psoriasis, studies on chronic toxicity and pharmacokinetics will have to be conducted.
Further clinical trials should evaluate a single Allomaleic acid derivative instead of mixtures.

Other uses:
Allomaleic acid is used in the manufacture of polyester resins and polyhydric alcohols and as a mordant for dyes.
When Allomaleic acid is added to their feed, lambs produce up to 70% less methane during digestion.

Industrial Processes with risk of exposure:
Pulp and Paper Processing
Painting (Pigments, Binders, and Biocides)
Textiles (Printing, Dyeing, or Finishing)

Typical Properties of Allomaleic acid:

Physical Properties:
Allomaleic acid mostly appears as a white-colored solid.
Allomaleic acid has a fruit-like odor.

The molecular weight of Allomaleic acid is 116 amu.
Allomaleic acid is Combustible but Allomaleic acid is difficult to start a fire.

Allomaleic acid undergoes sublimation at 200 C.
The melting point of Allomaleic acid is 572 to 576 °F.

Chemical Properties:
Allomaleic acid is soluble in ethanol and concentrated sulfuric acid.
Allomaleic acid is soluble in alcohol but is insoluble in benzene, water, and chloroform.

The capacity to absorb atmospheric moisture is very less.
The pH of Allomaleic acid is 3.19
When Allomaleic acid is heated in presence of Bayers reagent Allomaleic acid gives rise to Racemic Tartaric Acid.

Characteristics of Allomaleic acid:
One of Allomaleic acid properties is to inhibit or block malolactic fermentation at a certain concentration.
Allomaleic acid is therefore a tool of choice to limit the use of the SO2 previously used for this purpose.

Synthesis and Reactions of Allomaleic acid:
Allomaleic acid was first prepared from succinic acid.
A traditional synthesis involves oxidation of furfural (from the processing of maize) using chlorate in the presence of a vanadium-based catalyst.

Currently, industrial synthesis of Allomaleic acid is mostly based on catalytic isomerisation of maleic acid in aqueous solutions at low pH.
Maleic acid is accessible in large volumes as a hydrolysis product of maleic anhydride, produced by catalytic oxidation of benzene or butane.

The chemical properties of Allomaleic acid can be anticipated from Allomaleic acid component functional groups.
This weak acid forms a diester, Allomaleic acid undergoes additions across the double bond, and Allomaleic acid is an excellent dienophile.

Allomaleic acid does not combust in a bomb calorimeter under conditions where maleic acid deflagrates smoothly.
For teaching experiments designed to measure the difference in energy between the cis- and trans- isomers, a measured quantity of carbon can be ground with the subject compound and the enthalpy of combustion computed by difference.

Formula of Allomaleic acid:
The Allomaleic acid formula, also named as Fumaric acid formula is discussed in this article.
Allomaleic acid is a dicarboxylic acid and a conjugate acid of fumarate.
The molecular or chemical formula of Allomaleic acid is C4H4O4.

Allomaleic acid is a precursor to L-malate in the TCA cycle.
Allomaleic acid is generated by oxidizing succinic acid using succinate dehydrogenase.

Fumarate is converted to malate by the enzyme fumarase.
High levels of Allomaleic acid is present in biofluids surrounding tumours or inside the tumours.

Manufacturing Methods of Allomaleic acid:
Commercially, Allomaleic acid may be prepared from glucose by the action of fungi such as Rhizopus nigricans, as a by-product in the manufacture of maleic and phthalic anhydrides, and by the isomerization of maleic acid using heat or a catalyst.
On the laboratory scale, Allomaleic acid can be prepared by the oxidation of furfural with sodium chlorate in the presence of vanadium pentoxide.

Maleic acid or maleic anhydride, especially the maleic acid-containing wash water from the production of maleic anhydride or phthalic anhydride, serves as starting material for the manufacture of Allomaleic acid.
The maleic acid concentration should be at least 30%.

Maleic acid is converted almost quantitatively by thermal or catalytic isomerization into the sparingly soluble Allomaleic acid, which is recovered by filtration.
Various substances have been proposed as catalysts: mineral acids (e.g., hydrochloric acid); sulfur compounds such as thiocyanates, thiazoles, thiosemicarbazides, thioureas; or bromine compounds in combination with peroxides (e.g., persulfate).

Thiourea is most commonly used in practice.
The maleic acid-containing wash water contains impurities that can affect quality and yield.

This problem can be largely avoided (1) by thermal pretreatment of the wash water, (2) by adding urea if thiourea is used as catalyst, and (3) by addition of sulfites or passaged of sulfur dioxide and addition of mineral acids.
The crude Allomaleic acid obtained is purified by recrystallization from water, combined with purification by active charcoal.
Losses during purification are about 10%.

General Manufacturing Information of Allomaleic acid:

Industry Processing Sectors:
Agriculture, Forestry, Fishing and Hunting
All Other Basic Organic Chemical Manufacturing
Asphalt Paving, Roofing, and Coating Materials Manufacturing
Construction
Food, beverage, and tobacco product manufacturing
Not Known or Reasonably Ascertainable
Oil and Gas Drilling, Extraction, and Support activities
Paint and Coating Manufacturing
Plastics Material and Resin Manufacturing
Textiles, apparel, and leather manufacturing

Human Metabolite Information of Allomaleic acid:

Tissue Locations:
Placenta
Prostate

Cellular Locations:
Extracellular
Membrane
Mitochondria

Biosynthesis and Occurrence of Allomaleic acid:
Allomaleic acid is produced in eukaryotic organisms from succinate in complex 2 of the electron transport chain via the enzyme succinate dehydrogenase.
Allomaleic acid is one of two isomeric unsaturated dicarboxylic acids, the other being maleic acid.
In Allomaleic acid the carboxylic acid groups are trans (E) and in maleic acid they are cis (Z).

Allomaleic acid is found in fumitory (Fumaria officinalis), bolete mushrooms (specifically Boletus fomentarius var. pseudo-igniarius), lichen, and Iceland moss.

Fumarate is an intermediate in the citric acid cycle used by cells to produce energy in the form of adenosine triphosphate (ATP) from food.
Allomaleic acid is formed by the oxidation of succinate by the enzyme succinate dehydrogenase.
Fumarate is then converted by the enzyme fumarase to malate.

Human skin naturally produces Allomaleic acid when exposed to sunlight.
Fumarate is also a product of the urea cycle.

Handling and storage of Allomaleic acid:

Conditions for safe storage, including any incompatibilities:

Storage conditions:
Tightly closed.
Dry.

Storage class:
Storage class (TRGS 510): 11: Combustible Solids

Stability and Reactivity of Allomaleic acid:

Reactivity
Forms explosive mixtures with air on intense heating.
A range from approx. 15 Kelvin below the flash point is to be rated as critical.

The following applies in general to flammable organic substances and mixtures:
In correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Chemical stability:
Allomaleic acid is chemically stable under standard ambient conditions (room temperature).

Possibility of hazardous reactions:

Violent reactions possible with:
Oxidizing agents
Bases
Reducing agents
Amines

Conditions to avoid:
Strong heating.

Incompatible materials:
No data available

Safety of Allomaleic acid:
Allomaleic acid is "practically non-toxic" but high doses are probably nephrotoxic after long-term use.

First Aid Measures of Allomaleic acid:

EYES:
First check the victim for contact lenses and remove if present.
Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center.

Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN:
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing.
Gently wash all affected skin areas thoroughly with soap and water.
If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital.

Provide proper respiratory protection to rescuers entering an unknown atmosphere.
Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION:
DO NOT INDUCE VOMITING.
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center.

Be prepared to transport the victim to a hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body.

DO NOT INDUCE VOMITING.
IMMEDIATELY transport the victim to a hospital.

Fire Fighting of Allomaleic acid:
Use water spray, dry powder, foam, carbon dioxide.

Fire Fighting Procedures:

If material on fire or involved in fire:
Use water in flooding quantities as fog.
Solid streams of water may spread fire.

Cool all affected containers with flooding quantities of water.
Apply water from as far a distance as possible.
Use foam, dry chemicals, or carbon dioxide.

Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special protective equipment for fire-fighters:
Wear self contained breathing apparatus for fire fighting if necessary.

Accidental release measures of Allomaleic acid:

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel:
Avoid inhalation of dusts.
Avoid substance contact.

Ensure adequate ventilation.
Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental precautions:
Do not let product enter drains.

Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.

Observe possible material restrictions.
Take up dry.

Dispose of properly.
Clean up affected area.
Avoid generation of dusts.

Identifiers of Allomaleic acid:
CAS Number: 110-17-8
Beilstein Reference: 605763
ChEBI: CHEBI:18012
ChEMBL: ChEMBL503160
ChemSpider: 10197150
DrugBank: DB04299
ECHA InfoCard: 100.003.404
EC Number: 203-743-0
E number: E297 (preservatives)
Gmelin Reference: 49855
KEGG: C00122
PubChem CID: 444972
RTECS number: LS9625000
UNII: 88XHZ13131
UN number: 9126
CompTox Dashboard (EPA): DTXSID3021518
InChI: InChI=1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1+
Key: VZCYOOQTPOCHFL-OWOJBTEDSA-N
InChI=1/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1+
Key: VZCYOOQTPOCHFL-OWOJBTEDBF
SMILES: C(=C/C(=O)O)\C(=O)O

CAS number: 110-17-8
EC index number: 607-146-00-X
EC number: 203-743-0
Grade: ChP,NF,JPE
Hill Formula: C₄H₄O₄
Chemical formula: HOOCCHCHCOOH
Molar Mass: 116.07 g/mol
HS Code: 2917 19 80

Synonym(s): (2E)-2-Butenedioic acid, trans-Butenedioic acid
Linear Formula: HOOCCH=CHCOOH
CAS Number: 110-17-8
Molecular Weight: 116.07
Beilstein: 605763
EC Number: 203-743-0
MDL number: MFCD00002700
eCl@ss: 39021709
PubChem Substance ID: 329757345
NACRES: NA.21

Properties of Allomaleic acid:
Chemical formula: C4H4O4
Molar mass: 116.072 g·mol−1
Appearance: White solid
Density: 1.635 g/cm3
Melting point: 287 °C (549 °F; 560 K) (decomposes)
Solubility in water: 4.9 g/L at 20 °C
Acidity (pKa): pka1 = 3.03, pka2 = 4.44 (15 °C, cis isomer)
Magnetic susceptibility (χ): −49.11·10−6 cm3/mol
Dipole moment: non zero

vapor pressure: 1.7 mmHg ( 165 °C)
Quality Level: 200
grade: purum
Assay: ≥99.0% (T)
form: powder
autoignition temp.: 1364 °F
expl. lim.: 40 %
mp: 298-300 °C (subl.) (lit.)
solubility: 95% ethanol: soluble 0.46 g/10 mL, clear, colorless
SMILES string: OC(=O)\C=C\C(O)=O
InChI: 1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1+
InChI key: VZCYOOQTPOCHFL-OWOJBTEDSA-N

Boiling point: 290 °C (1013 hPa) (sublimed)
Density: 1.64 g/cm3 (20 °C)
Flash point: 273 °C
Ignition temperature: 375 °C
Melting Point: 287 °C
pH value: 2.1 (4.9 g/l, H₂O, 20 °C)
Vapor pressure: Solubility: 4.9 g/l

Molecular Weight: 116.07 g/mol
XLogP3: -0.3
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 116.01095860 g/mol
Monoisotopic Mass: 116.01095860 g/mol
Topological Polar Surface Area: 74.6Ų
Heavy Atom Count: 8
Complexity: 119
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 1
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Allomaleic acid:
Assay (calc. on anhydrous substance): 99.5 - 100.5 %
Assay (HPLC; calc. on anhydrous substance): 98.0 - 102.0 %
Identity (IR): passes test
Identity (JPE 1): passes test
Identity (JPE 2/ChP 1): passes test
Identity (JPE 3): passes test
Identity (HPLC): passes test
Appearance of solution: passes test
Sulfate (SO₄): ≤ 0.010 %
Heavy metals (as Pb): ≤ 10 ppm
As (Arsenic): ≤ 2 ppm
Malic acid (HPLC) (NF): ≤ 1.5 %
Maleic acid (HPLC) (NF): ≤ 0.1 %
Maleic acid (HPLC) (JPE): passes test
Maleic acid (HPLC) (ChP): ≤ 0.1 %
Any individual unspecified impurity (HPLC): ≤ 0.1 %
Sum of all impurities (HPLC): ≤ 0.2 %
Residual solvents (ICH Q3C): excluded by production process
Water (K. F.): ≤ 0.5 %
Sulfated ash: ≤ 0.05 %

Related Products of Allomaleic acid:
Telaglenastat (CB-839)New
Setanaxib (GKT137831)New
LB-100New
Puromycin 2HCl
Cyclosporin A
Cyclophosphamide Monohydrate
Ganciclovir
Calcitriol
Ribavirin (ICN-1229)
BAPTA-AM

Related Compounds of Allomaleic acid:
Fumaryl chloride
Fumaronitrile
Dimethyl fumarate
Ammonium fumarate
Iron(II) fumarate

Related carboxylic acids:
Maleic acid
Succinic acid
Crotonic acid

Names of Fumaric acid:

Regulatory process names:
Fumaric acid
Fumaric acid
fumaric acid

Translated names:
acide fumarique (fr)
acido fumarico (it)
Fumaarhape (et)
Fumaarihappo (fi)
fumaarzuur (nl)
fumarna kiselina (hr)
fumarna kislina (sl)
fumaro rūgštis (lt)
fumarová kyselina (cs)
fumarsyra (sv)
fumarsyre (da)
fumarsyre (no)
Fumarsäure (de)
fumársav (hu)
fumārskābe (lv)
kyselina fumarová (sk)
ácido fumárico (es)
ácido fumárico (pt)
φουμαρικό οξύ (el)
фумарова киселина (bg)

IUPAC names:
(2E)-but-2-enedioic acid
(E) but-2-enedioic acid
(E)-but-2-enedioic acid
(E)-Butenedioic acid
1,2-ethylene dicarboxylic acid
2-BUTENEDIOIC ACID
2-Butenedioic acid (2E)-Fumaric acid
2-Butenedioic acid, E-
acide fumarique
But-2-enedioic acid
but-2-enedioic acid
E-butenedioic Acid
FA Flakes
FUMARIC ACID
Fumaric Acid
Fumaric acid
fumaric acid
Fumaric Acid
Fumaric acid
fumaric acid
fumaric acid ,Butenedioic acid , Allomaleic acid , Boletic acid , Donitic acid , Lichenic acid
Fumarsäure
trans-1,2-Ethylenedicarboxylic
trans-2-Butenedioïc acid
trans-Butendisäure
Trans-Butenedioic Acid

Preferred IUPAC name:
(2E)-But-2-enedioic acid

Trade names:
(E)-2-Butenedioic acid
1,2-ethylene dicarboxylic acid
Allomaleic acid
Boletic acid
Butenedioic acid, (E)-
Fumaric Acid
trans-1,2-Ethylenedicarboxylic acid
TRANS-BUTENEDICARBOXYLIC ACID

Other names:
Fumaric acid
trans-1,2-Ethylenedicarboxylic acid
2-Butenedioic acid
trans-Butenedioic acid
Allomaleic acid
Boletic acid
Donitic acid
Lichenic acid

Other identifiers:
110-17-8
607-146-00-X
623158-97-4
909873-99-0

Synonyms of Allomaleic acid:
fumaric acid
110-17-8
2-Butenedioic acid
trans-Butenedioic acid
Allomaleic acid
fumarate
Lichenic acid
Boletic acid
Tumaric acid
(2E)-but-2-enedioic acid
trans-1,2-Ethylenedicarboxylic acid
Allomalenic acid
But-2-enedioic acid
trans-2-Butenedioic acid
(E)-2-Butenedioic acid
Fumaricum acidum
2-Butenedioic acid, (E)-
Kyselina fumarova
Butenedioic acid
2-Butenedioic acid (E)-
USAF EK-P-583
Butenedioic acid, (E)-
FEMA No. 2488
(2E)-2-butenedioic acid
Caswell No. 465E
FEMA Number 2488
NSC-2752
Fumarsaeure
Allomaleic-acid
Boletic-acid
Lichenic acid (VAN)
2-Butenedioic acid (2E)-
1,2-Ethylenedicarboxylic acid, (E)
CCRIS 1039
HSDB 710
2-(E)-Butenedioic acid
Kyselina fumarova [Czech]
trans-but-2-enedioic acid
(E)-but-2-enedioic acid
U-1149
ammonium fumarate
(E)-Butenedioic acid
1,2-Ethenedicarboxylic acid, trans-
EPA Pesticide Chemical Code 051201
AI3-24236
6915-18-0
EINECS 203-743-0
fumarate, 10
BRN 0605763
Fumaric acid (NF)
Fumaric acid [NF]
INS NO.297
DTXSID3021518
UNII-88XHZ13131
CHEBI:18012
E-2-Butenedioic acid
Fumaric acid (8CI)
INS-297
NSC2752
ethylenedicarboxylic acid
FC 33 (acid)
88XHZ13131
E297
DTXCID601518
Maleic acid-2,3-13C2
E-297
2(TRANS)-BUTENEDIOIC ACID
EC 203-743-0
4-02-00-02202 (Beilstein Handbook Reference)
fum
Maleic-2,3-d2 acid
F0067
FUMARIC ACID (II)
FUMARIC ACID [II]
(E)-2-Butenedioate
Fumaric acid 1000 microg/mL in Acetonitrile:Water
FUMARIC ACID (MART.)
FUMARIC ACID [MART.]
FUMARIC ACID (USP-RS)
FUMARIC ACID [USP-RS]
(2E)-but-2-enedioate
FUMARIC ACID (USP IMPURITY)
FUMARIC ACID [USP IMPURITY]
Donitic acid
but-2-enedioicacid
CAS-110-17-8
trans-1,2-Ethenedicarboxylic acid
MALIC ACID IMPURITY A (EP IMPURITY)
MALIC ACID IMPURITY A [EP IMPURITY]
(E)-1,2-Ethylenedicarboxylic acid
trans-1,2-Ethylenediccarboxylic acid
SODIUM AUROTHIOMALATE IMPURITY B (EP IMPURITY)
SODIUM AUROTHIOMALATE IMPURITY B [EP IMPURITY]
fumarsaure
Allomaleate
Boletate
Lichenate
Acide fumarique
Acido lichenico
fumeric acid
Acido boletico
Acido fumarico
Acidum fumaricum
Acido allomaleico
trans-Butenedioate
NCGC00091192-02
24461-33-4
26099-09-2
Fumaric Acid,(S)
MFCD00002700
trans-2-Butendisaure
trans-2-Butenedioate
2-(E)-Butenedioate
Fumaric acid, 99%
Acido trans butendioico
FUM (CHRIS Code)
trans-Ethylendicarbonsaure
(Trans)-butenedioic acid
Fumaric acid, >=99%
FEMA Number: 2488
bmse000083
D03GOO
FUMARIC ACID [MI]
WLN: QV1U1VQ-T
FUMARIC ACID [FCC]
Futrans-2-Butenedioic Acid
SCHEMBL1177
FUMARIC ACID [FHFI]
FUMARIC ACID [HSDB]
FUMARIC ACID [INCI]
FUMARIC ACID [VANDF]
MLS002454406
1,2-ethylenedicarboxylic acid
2-butenedioic acid, (2E)-
(2E)-2-Butenedioic acid #
S04-0167
FUMARIC ACID [WHO-DD]
CHEMBL503160
FUMARICUM ACIDUM [HPUS]
trans-1,2-Ethylenedicarboxylate
BDBM26122
CHEBI:22958
2-Butenedioic acid (2E-(9CI)
HMS2270C12
Pharmakon1600-01301022
Fumaric acid, >=99.0% (T)
AMY30339
STR02646
Acido trans 1,2-etenedicarbossilico
Tox21_201769
Tox21_302826
2-Butenedioic acid (2E)- (9CI)
Acido trans 1,2-etilendicarbossilico
Fumaric acid, >=99%, FCC, FG
LS-500
NA9126
NSC760395
s4952
AKOS000118896
Fumaric acid, qNMR Standard for DMSO
CCG-266065
CS-W016599
DB01677
HY-W015883
NSC-760395
OR17920
USEPA/OPP Pesticide Code: 051201
NCGC00091192-01
NCGC00091192-03
NCGC00256360-01
NCGC00259318-01
BP-13087
Fumaric acid, tested according to USP/NF
SMR000112117
Fumaric acid, puriss., >=99.5% (T)
EN300-17996
Fumaric acid, Vetec(TM) reagent grade, 99%
1, (E)
C00122
D02308
D85166
Q139857
Fumaric acid, BioReagent, suitable for cell culture
J-002389
Fumarate; 2-Butenedioic acid; Trans-Butenedioic acid
Z57127460
F8886-8257
Fumaric acid, certified reference material, TraceCERT(R)
26B3632D-E93F-4655-90B0-3C17855294BA
Fumaric acid, anhydrous, free-flowing, Redi-Dri(TM), >=99%
Fumaric acid, European Pharmacopoeia (EP) Reference Standard
Fumaric acid, United States Pharmacopeia (USP) Reference Standard
Fumaric Acid, Pharmaceutical Secondary Standard; Certified Reference Material
623158-97-4
Fumaric acid [Wiki]
(2E)-2-Butendisäure [German] [ACD/IUPAC Name]
(2E)-2-Butenedioic acid [ACD/IUPAC Name]
(2E)-But-2-enedioic acid
(E)-1,2-Ethylenedicarboxylic acid
(E)-2-Butenedioic acid
(E)-Butenedioic acid
1,2-Ethenedicarboxylic acid, trans-
110-17-8 [RN]
203-743-0 [EINECS]
2-Butenedioic acid [ACD/IUPAC Name]
2-Butenedioic acid (2E)-
2-Butenedioic acid, (2E)- [ACD/Index Name]
2-Butenedioic acid, (E)-
605763 [Beilstein]
Acide (2E)-2-butènedioïque [French] [ACD/IUPAC Name]
Acidum fumaricum
Butenedioic acid, (E)-
E-2-Butenedioic acid
MFCD00002700 [MDL number]
trans-1,2-ethenedicarboxylic acid
trans-1,2-ethylenedicarboxylic acid
TRANS-2-BUTENEDIOIC ACID
trans-but-2-enedioic acid
trans-Butenedioic acid
(2E)-But-2-enedioate
(E)-2-Butenedioate
(E)-but-2-enedioate
(E)-but-2-enedioic acid
(E)-HO2CCH=CHCO2H
1,2-Ethylenedicarboxylic acid, (E)
2-(E)-Butenedioate
2-(E)-Butenedioic acid
2-Butenedioic acid (E)-
4-02-00-02202 [Beilstein]
605762 [Beilstein]
Allomalenic acid
Boletate
Boletic acid
cis-Butenedioic acid
Fumaric acidmissing
Fumaricum acidum
Fumarsaeure
Kyselina fumarova [Czech]
Lichenate
Lichenic acid (VAN)
phenanthrene-9,10-dione
phenanthrene-9,10-dione;9,10-Phenanthraquinone
QV1U1VQ-T [WLN]
STR02646
trans-1,2-Ethylenedicarboxylate
trans-1,2-Ethylentricarboxylic acid
trans-2-Butenedioate
trans-Butenedioate
延胡索酸 [Chinese]
ALLURA RED
C.I. Food red 17; C.I. 16035; D & C Red 40; Disodium 6-hydroxy- 5-[(2-methoxy-4-sulphonato-m-tolyl)azo]naphthalene- 2-sulphonate; Disodium 6-hydroxy-5-(2-methoxy-5-methyl-4-sulfonato- phenylazo)-2- naphthalene sulfonate; 2-Naphthalenesulfonic Acid 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfophenyl) Azo)-, Disodium Salt; Allura Red AC CAS NO: 25956-17-6
ALLURA RED AC
CAS Number: 25956-17-6
EC Number: 247-368-0
E number: E129
Molecular formula: C18H14N2Na2O8S2
Formula weight: 496.43

Allura Red AC is a red azo dye that goes by several names, including FD&C Red 40.
Allura Red AC is used as a food dye and has the E number E129.
Allura Red AC is usually supplied as its red sodium salt, but can also be used as the calcium and potassium salts.
These salts like Allura Red AC are soluble in water.
In solution, Allura Red ACs maximum absorbance lies at about 504 nm.

Applications of Allura Red AC:
Allura Red AC has been used:
-for the determination of fecal neutral sterols (FNS) in mice
-to evaluate its developmental toxicity
-as a coloring reagent for observing the experimental performance of liquid-handling robot

Allura Red AC is a lab-manufactured dye that’s used as a colorant in food, cosmetics, over-the-counter medicines, and even prescription drugs.
Allura Red AC’s what creates the bright red color in sodas, sauces, and cherry-flavored cough syrups.
Allura Red AC’s often the red used to color cosmetics and other items used on the skin, as well.
Allura Red AC is what is commonly used for things like cosmetics, red medicine coatings, candy coatings, and other solids.
Allura Red comprises disodium 2-hydroxy-1-nephthalene-6-sulfonate and is supported by subsidiary coloring matters in combination with sodium chloride/sodium sulfate as principal uncolored component. As a sodium salt, the organic compounds other than coloring matters it contains include 6-hydroxy-2-naphthalene sulfonic acid, sodium salt (Not more than 0.3%); 6,6-oxybis disodium salt (Not more than 0.1%) and 4-amino-5-methoxy-2-methylbenzene sulfonic acid (Not more than 0.2%).

Description of Allura Red AC:
FD & C Red No. 40 is principally the disodium salt of 6-hydroxy5-[(2-methoxy-5-methyl-4-sulfophenyl)azo]2-napthalenesulfonic acid.
The colorant is a red powder that dissolves in water to give a solution red at neutrality and in acid and dark red in base.
Allura Red AC is slightly soluble in 95% ethanol.

Allura Red AC is primarily an artificial colorant. And it provides a deep red color to the product.
Allura Red AC is available in powder or granular form. Very good water solubility.
Allura Red AC is insoluble in ethanol.
Allura Red AC is also called synthetic azo dye.
Allura Red AC can come across with names such as Allura red, CI Food Red 17.

Not all of the foods with Allura Red AC are red.
You will also find it in brown, blue, green, orange, and even white food products, too.
Take pickles for example.
A combination of artificial dyes, including Allura Red AC, are used to give some pickles a more pronounced yellow-green color.

Can find Allura Red AC in a wide range of foods and beverages, including:
-Candy
-Condiments
-Snack foods
-Baked goods
-Beverages
-Salad dressings
-Dairy products
-Frozen desserts
-Breakfast cereals
-Fruit bars
-Sauces

Red 40 is a food color additive that manufacturers use to control the color of their products. Specifically, Red 40 makes food the color red.
The food coloring dye also comes with other names such as Allura Red AC, FD&C Red 40, Food Red 17, Cosmetic Ingredient 16035, and E129.
A synthetic azo dye, the chemical structure of Red 40 makes this compound soluble in water as well as having a dark red color.
Under a spectrophotometer, Allura Red ACs absorbance is about 504 nm which appropriately puts the compound in the range of the red color spectrum.

Uses of Allura Red AC:
Allura Red AC is a colorant.
Allura Red AC has good stability to ph changes from ph 3 to 8, showing no appreciable change.
Allura Red AC has excellent solubility in water with a solubility of 22 g/100 ml at 25°c.

Allura Red AC has very good stability to light, fair to poor stability to oxidation, good stability to heat, and shows no appreciable change in stability in 10% sugar systems.
Allura Red AC has a yellowish-red hue and has a very good tinctorial strength.
Allura Red AC has very good compatibility with food components and is used in beverages, desserts, candy, confections, cereals, and ice cream.

Allura Red AC, a food colourant, is dark red and water-soluble powder or granules used in various applications, such as in drinks, syrups, sweets and cereals.
Allura Red AC has the ability to quench the intrinsic fluorescence of HSA through static quenching.

Purpose of Allura Red AC:
Allura Red AC is an artificial dye used to colour foods, medications, and cosmetics.

Description of Allura Red AC:
Byproducts of the petroleum industry are used to produce allura red.
In fact, many organic compounds used in food additives and pharmaceuticals come from petroleum products.
Allura Red AC looks like a dark red powder.

Common Uses of Allura Red AC:
Allura Red AC is commonly used in many processed foods including baked goods, candy, cereal, dairy products, drinks, sauces, and snacks.
Allura Red AC is a red azo dye that goes by several names, including FD&C Red 40.
Allura Red AC is used as a food dye and has the E number E129.
Allura Red AC is usually supplied as its red sodium salt, but can also be used as the calcium and potassium salts.
These salts are soluble in water. In solution, its maximum absorbance lies at about 504 nm.

Use as food color of Allura Red AC:
Allura Red AC is a popular dye used worldwide. Annual production in 1980 was greater than 2.3 million kilograms.
The European Union approves Allura Red AC as a food colorant.
In the United States, Allura Red AC is approved by the FDA for use in cosmetics, drugs, and food.
When prepared as a lake it is disclosed as Red 40 Lake or Red 40 Aluminum Lake.

Allura Red AC is used in some tattoo inks and is used in many products, such as cotton candy, soft drinks, cherry flavored products, children's medications, and dairy products.
Allura Red AC is by far the most commonly used red dye in the United States, completely replacing amaranth (Red 2) and also replacing erythrosine (Red 3) in most applications.
Allura Red AC is a red azo dye which looks like a dark red powder and used as a food dye.
Ungraded products supplied by TCI America are generally suitable for common industrial uses or for research purposes but typically are not suitable for human consumption or therapeutic use.

USES of Allura Red AC:
Relatived to the maintenance and repair of automobiles, products for cleaning and caring for automobiles (auto shampoo, polish/wax, undercarriage treatment, brake grease)
Related to products specifically designed for children (e.g. toys, children's cosmetics, etc)
Related to all forms of cleaning/washing, including cleaning products used in the home, laundry detergents, soaps, de-greasers, spot removers, etc; modifiers included when specific information is known, such as drycleaning, laundry, soap, window/floor, etc
Term used for colorants, dyes, or pigments; includes colorants for drugs, textiles, personal care products (cosmetics, tatoo inks, hair dye), food colorants, and inks for printing; modifiers included when application is known

Allura Red AC can be used in many products.
Allura Red AC is widely used in confectionery.
Apart from that, it can be used in bakery products, flavored drinks, edible ice, desserts, meat products, dried fruits and vegetables.
Apart from the food sector, it is used in pharmacy, cosmetics and in the toy industry (play dough).

Use as a consumable coloring agent
Allura Red AC is a popular dye used worldwide. Annual production in 1980 was greater than 2.3 million kilograms.

Allura Red AC is a synthetic color additive or food dye made from petroleum .
Allura Red AC is one of the nine certified color additives approved by the Food and Drug Administration (FDA) for use in foods and beverages (2Trusted Source).
Allura Red AC is also approved as a food dye for use within the European Union (3).
Certified color additives must undergo FDA certification every time a new batch is produced to ensure they contain what they’re legally supposed to.

Conversely, exempt color additives do not require batch certification, but the FDA must still approve them before they can be used in foods or beverages.
Exempt color additives come from natural sources, such as fruits, vegetables, herbs, minerals, and insects .
Manufacturers use color additives in foods and beverages to enhance naturally occurring colors, add color for visual appeal, and offset color loss that may occur due to storage conditions.
Compared with their natural alternatives, synthetically produced color additives provide a more uniform color, blend easier, are cheaper, and do not add undesirable flavors .
For this reason, synthetic color additives are used more widely than natural color additives.

How to identify Allura Red AC?
As one of the most widely used color additives, Allura Red AC is found in a variety of foods and beverages, including :
Dairy products: flavored milk, yogurt, puddings, ice cream, and popsicles
Sweets and baked goods: cakes, pastries, candy, and chewing gum
Snacks and other items: breakfast cereals and bars, jello, fruit snacks, chips
Beverages: soda, sports drinks, energy drinks, and powdered drink mixes, including some protein powders
According to studies, breakfast cereals, juice drinks, soft drinks, baked goods, and frozen dairy desserts are the greatest contributors of synthetic food dyes in the diet.
Like other color additives, Allura Red AC is also used in the production of cosmetics and pharmaceuticals (4Trusted Source).

You can identify Allura Red AC by reading the ingredient list. Allura Red AC’s also known as:
Red 40
Red 40 Lake
FD&C Red No. 40
FD&C Red No. 40 Aluminum Lake
Allura Red AC
CI Food Red 17
INS No. 129
E129

While manufacturers are not required to list the amount of an ingredient used, they must list ingredients in descending order by weight.
This means that the first ingredient listed contributes the most by weight while the last ingredient listed contributes the least.
Allura Red AC (E129) is an azo dye that widely used in drinks, juices, bakery, meat, and sweets products.
High consumption of Allura Red has claimed an adverse effects of human health including allergies, food intolerance, cancer, multiple sclerosis, attention deficit hyperactivity disorder, brain damage, nausea, cardiac disease and asthma due to the reaction of aromatic azo compounds (R = R′ = aromatic).
Several countries have banned and strictly controlled the uses of Allura Red in food and beverage products.
This review paper is critically summarized on the available analytical and advanced methods for determination of Allura Red and also concisely discussed on the acceptable daily intake, toxicology and extraction methods.

Physical Description of Allura Red AC:
Allura Red AC is principally the disodium salt of 6-hydroxy-5-[(2-methoxy-5-methyl-4-sulfophenyl)azo]-2-naphthalenesulfonic acid.
Allura red is an orange red dye that has a red to brownish shade in applications.

Common Uses of Allura Red AC:
Allura Red AC is used in cereal, beverages, gelatins, puddings, dairy products, frozen treats, powder mixes, icings, jellies, spices, dressings, sauces, baked goods and confections.
FD&C Red No.
40 is also used in pharmaceuticals and cosmetics.
Allura Red AC is a synthetic colouring agent that belongs to the class of monoazo dyes.

Manufacturing process of Allura Red AC:
Allura Red AC is manufactured by coupling diazotized 5-amino-4-methoxy-2-toluenesulphonic acid (also called 4-amino-5-methoxy-2-methylbenzenesulfonic acid or p-cresidine sulfonic acid, p-CSA) with 6- hydroxy-2-naphthalene sulphonic acid (the sodium salt is called Shaeffer’s salt) (HSDB, 2006). The resulting dye is purified and isolated as the sodium salt.
Allura Red AC may be converted to the corresponding aluminium lake under aqueous conditions by
reacting aluminium oxide with the colouring matter. Undried aluminium oxide is usually freshly prepared by reacting aluminium sulfate or aluminium chloride with sodium carbonate or sodium bicarbonate, or aqueous ammonia. Following lake formation, the product is filtered, washed with water, and dried.

Molecular formula C18H14N2Na2O8S2
Formula weight 496.43
CAS Registry Number 25956-17-6
Chemical name Disodium 6-hydroxy-5-[(2-methoxy-5-methyl-4-
sulfophenyl)azo]-2-naphthalenesulfonate
Synonyms Allura Red, Allura Red AC, INS No. 129, CI Food Red 17, CI
16035 (Colour Index, 1975), Food Red No. 40, E 129, certified
by USA as FD&C Red No. 40
Assay Not less than 85% total colouring matters
Description Dark red powder or granules
Functional uses Colour
Solubility Freely soluble in water and slightly soluble in 50% ethanol

Functional use
Allura Red AC is allowed as a food colour in the EU, Japan, Australia, USA, and other regions.
Allura Red AC is used in various types of foods including beverages, frozen treats, powder mixes, gelatin products, candies, icings, jellies, spices, dressings, sauces, baked goods, and dairy products

General description
Allura Red AC is a food azo dye.
Allura Red AC is a dark red powder or granules, that is soluble in water and insoluble in ethanol.

Chemical Properties
Red powder

Uses
Color additive in foods, drugs and cosmetics. Allura Red AC is used as a food dye and has the E number E129.

Uses
Color additive in foods, drugs and cosmetics.

Pharmaceutical related
-Includes spices, extracts, colorings, flavors, etc added to food for human consumption
-Personal care products, including cosmetics, shampoos, perfumes, soaps, lotions, toothpastes, etc
-General term used only when enough information is not provided to assign a more specific beauty/cosmetics/personal_care related term
-Subcategory of personal_care, includes fragrances, shampoos, make-up, etc.; appropriate modifiers included when known
-Products specifically designed for use by babies (includes diapers, baby toys, baby clothing, baby food, etc., with appropriate modifiers)
-General term used only when enough information is not provided to assign a more specific beauty/cosmetics/personalcare related term
-Products specifically designed for use by babies (includes diapers, baby toys, baby clothing, baby food, etc., with appropriate modifiers)
-Personal care products for general use on the body (body makeup, body powder, body treatments, body cleansers)

Oil-based or oil-soluble Allura Red AC food coloring, which is in the class of synthetic food dyes, is used in limited quantities in products permitted in the food codex.
Allura Red AC is used in ice cream production, iced beverages, carbonated drinks when necessary, fruit soda production.
In addition, it is used in the production of confectionery products, jellies, flavored beverages, chewing gum varieties with sugar and low sugar, bakery products, pastry, etc. in many food production.
Apart from food, it is also used in the coloring of many products that come into contact with people, such as medicine, cosmetics, detergent products, auto care products, very small amount of agricultural products, cleaning products, colored stones, play dough, etc.
Allura Red AC gives a bright red color and this food coloring is soluble in oil.

The European Union approves Allura Red AC as a food colorant, but EU countries' local laws banning food colorants are preserved. In the United States, Allura Red AC is approved by the FDA for use in cosmetics, drugs, and food. When prepared as a lake it is disclosed as Red 40 Lake or Red 40 Aluminum Lake.
Allura Red AC is used in some tattoo inks and is used in many products, such as cotton candy, soft drinks, cherry flavored products, children's medications, and dairy products.
Allura Red AC is occasionally used to dye medicinal pills, such as the antihistamine fexofenadine, for purely aesthetic reasons.
Allura Red AC is by far the most commonly used red dye in the United States, completely replacing amaranth (Red 2) and also replacing erythrosine (Red 3) in most applications due to the negative health effects of those two dyes.

Consumer Uses
Allura Red AC is used in the following products: biocides (e.g. disinfectants, pest control products), fertilisers, plant protection products, cosmetics and personal care products, inks and toners, washing & cleaning products, air care products and textile treatment products and dyes.
Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Article service life
Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).
Allura Red AC can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture), metal (e.g. cutlery, pots, toys, jewellery), wood (e.g. floors, furniture, toys) and plastic (e.g. food packaging and storage, toys, mobile phones).

Widespread uses by professional workers
Allura Red AC is used in the following products: inks and toners, cosmetics and personal care products, paper chemicals and dyes, textile treatment products and dyes, plant protection products, biocides (e.g. disinfectants, pest control products), fertilisers, washing & cleaning products, non-metal-surface treatment products, leather treatment products and water treatment chemicals.
Allura Red AC is used in the following areas: agriculture, forestry and fishing, printing and recorded media reproduction and building & construction work.

Allura Red AC is used for the manufacture of: textile, leather or fur, wood and wood products, food products and pulp, paper and paper products.
Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Formulation or re-packing
Allura Red AC is used in the following products: cosmetics and personal care products.
Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

Uses at industrial sites
Allura Red AC is used in the following products: washing & cleaning products, inks and toners, paper chemicals and dyes, textile treatment products and dyes, metal surface treatment products, biocides (e.g. disinfectants, pest control products), coating products, fillers, putties, plasters, modelling clay, fertilisers, plant protection products, leather treatment products and water treatment chemicals.
Allura Red AC is used in the following areas: agriculture, forestry and fishing and building & construction work.

Allura Red AC is used for the manufacture of: textile, leather or fur, wood and wood products, pulp, paper and paper products, chemicals and plastic products.
Release to the environment of this substance can occur from industrial use: in the production of articles and in processing aids at industrial sites.

Allura Red AC consists essentially of disodium 2-hydroxy-1-(2-methoxy-5-methyl-4-sulfonato-phenylazo) naphthalene-6-sulfonate and subsidiary colouring matters together with sodium chloride and/or sodium sulphate as the principal uncoloured components.
Allura Red AC is manufactured by coupling diazotized 5-amino-4-methoxy-2-toluenesulphonic acid with 6-hydroxy-2-naphthalene sulphonic acid; Allura Red AC is described as the sodium salt.
The calcium and the potassium salt are also permitted.

IUPAC NAMES:
Allura Red AC; FD&C Red 40
disodium (5E)-5-[2-(2-methoxy-5-methyl-4-sulfonatophenyl)hydrazin-1-ylidene]-6-oxo-5,6-dihydronaphthalene-2-sulfonate
disodium 6-hydroxy-5-[(2-methoxy-3-methyl-4-sulfonatophenyl)diazenyl]naphthalene-2-sulfonate
Disodium 6-hydroxy-5-[(2-methoxy-4-sulphonato-m-tolyl)azo]naphthalene-2-sulphonate
disodium 6-hydroxy-5-[(E)-2-(2-methoxy-5-methyl-4-sulfophenyl)diazen-1-yl]naphthalene-2-sulfonate

SYNONYMS:
Allura Red AC
25956-17-6
Allura Red
Allura red AC dye
C.I. Food Red 17
Food red 17
Food Red No. 40
FD&C Red No. 40
Curry red
ALLURA RED C.I.16035
UNII-WZB9127XOA
CI 16035
Red No. 40
FD and C Red No. 40
FD & C Red no. 40
WZB9127XOA
MFCD00059526
2-Naphthalenesulfonic acid, 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfophenyl)azo)-, disodium salt
E129
CI 16035; Food Red 17; Fancy Red;
Fancy Red
Disodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfophenyl)azo)-2-naphthalenesulfonate
Allura Red 40
FDC Red 40
CHEMBL174821
Japan Food Red No. 40
Disodium 6-hydroxy-5-[(2-methoxy-5-methyl-4-sulfophenyl)azo]-2-naphthalenesulfonate
2-Naphthalenesulfonic acid, 6-hydroxy-5-[(2-methoxy-5-methyl-4-sulfophenyl)azo]-, disodium salt
sodium (E)-6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate
C.I.16035
ALLURAREDAC
Japan Red 40
CCRIS 3493
HSDB 7260
disodium 6-hydroxy-5-[(E)-(2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl]naphthalene-2-sulfonate
disodium;6-hydroxy-5-[(E)-(2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl]naphthalene-2-sulfonate
2-Naphthalenesulfonic acid, 6-hydroxy-5-(2-(2-methoxy-5-methyl-4-sulfophenyl)diazenyl)-, sodium salt (1:2)
2-Naphthalenesulfonic acid, 6-hydroxy-5-[2-(2-methoxy-5-methyl-4-sulfophenyl)diazenyl]-, sodium salt (1:2)
Disodium 6-hydroxy-5-((6-methoxy-4-sulfo-m-tolyl)azo)-2-naphthalenesulfonate
2-Naphthalenesulfonic acid, 6-hydroxy-5-((6-methoxy-4-sulfo-m-tolyl)azo)-, disodium salt
Allura Red AC, analytical standard
Allura Red AC, Dye content 80 %
Disodium 6-hydroxy-5-((2-methoxy-4-sulphonato-m-tolyl)azo)naphthalene-2-sulphonate
Disodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfophenyl)azo)-2-naphthalene- sulfonate
Allura Red AC 100 microg/mL in Water
6-Hydroxy-5-((2-methoxy-5-methyl-4-sulfophenyl)azo)-2-naphthalene- sulfonic acid, disodium salt
Sodium 6-hydroxy-5-((2-methoxy-5-methyl-4-sulfonatophenyl)diazenyl)naphthalene-2-sulfonate
disodium;(5Z)-5-[(2-methoxy-5-methyl-4-sulfonatophenyl)hydrazinylidene]-6-oxonaphthalene-2-sulfonate
Allyl 2,3-epoxypropyl ether
agar gum; gelidium spp. gum; agar powder; agal agal gum ; agar high gel strength bacteriological grade; aloe wood gum; bengal gelatin cas no : 9002-18-0
ALLYL ACETOACETATE
Allyl Acetoacetate is an organic compound that is the simplest member of the acetic acid esters.
Allyl Acetoacetate is a clear colorless liquid.


CAS Number: 1118-84-9
EC Number: 214-269-9
MDL number: MFCD00009811
Linear Formula: CH3COCH2COOCH2CH=CH2
Molecular Formula: C7H10O3



SYNONYMS:
Allyl acetoacetate, 1118-84-9, Allyl 3-oxobutanoate, Allylacetoacetate, (2-Propenyl) 3-oxobutanoate, Allyl acetylacetate, Acetoacetic acid, allyl ester, Butanoic acid, 3-oxo-, 2-propenyl ester, prop-2-en-1-yl 3-oxobutanoate, prop-2-enyl 3-oxobutanoate, Acetoacetic Acid Allyl Ester, (2-Propenyl)3-oxobutanoate, 8HX066J62P, NSC-24280, 2-propenyl acetoacetate, UNII-8HX066J62P, AI3-04977, allyl aceto-acetate, EINECS 214-269-9, Allyl 3-oxobutanoate #, Allyl acetoacetate, 97%, Allyl acetoacetate, 98%, EC 214-269-9, SCHEMBL9513, Acetylacetic acid, allyl ester, 3-oxo-butyric acid allyl ester, DTXSID40149740, BCP12037, NSC24280, BBL011433, MFCD00009811, NSC 24280, STL146541, AKOS000120505, CS-W018294, VS-02949, DB-003129, NS00001809, EN300-20951, E75749, J-002655, J-519551, Q27270546, F0001-0255, Allyl acetoacetate, Prop-2-en-1-yl 3-oxobutanoate, Butanoic acid, 3-oxo-, 2-propen-1-yl ester, 1118-84-9, EINECS 214-269-9, Butanoic acid, 3-oxo-, 2-propen-1-yl ester, Acetoacetic acid, allyl ester, Butanoic acid, 3-oxo-, 2-propenyl ester, Allyl acetoacetate, Allyl acetylacetate, Allyl 3-oxobutanoate, NSC 24280, 3-Oxo-butyric acid allyl ester, Allyl acetoacetate, Acetoacetic acid allyl ester, allyl acetoacetate, allyl 3-oxobutanoate, allyl acetylacetate, acetoacetic acid, allyl ester, butanoic acid, 3-oxo-, 2-propenyl ester, prop-2-en-1-yl 3-oxobutanoate, acetoacetic acid allyl ester, 2-propenyl 3-oxobutanoate, ac-allyl, unii-8hx066j62p, prop-2-en-1-yl 3-oxobutanoate, allyl acetylacetate, 3-oxo-2-propenyl butanoic acid ester, Butanoic acid, 3-oxo-, 2-propenyl ester, [ChemIDplus] Allyl 3-oxobutanoate, allyl acetoacetate, allyl 3-oxobutanoate, allyl acetylacetate, acetoacetic acid, allyl ester, butanoic acid, 3-oxo-, 2-propenyl ester, prop-2-en-1-yl 3-oxobutanoate, acetoacetic acid allyl ester, 2-propenyl 3-oxobutanoate, ac-allyl, unii-8hx066j62p



Allyl Acetoacetate is an organic compound that is the simplest member of the acetic acid esters.
Allyl Acetoacetate can be synthesized by reacting allyl alcohol with hydrochloric acid and a particle.
Allyl Acetoacetate is a clear colorless liquid.


Allyl Acetoacetate has been shown to have cytotoxic effects on cardiac tissues, as well as certain reactive properties, which may be due to its ability to form cross-links with proteins.
Allyl Acetoacetate is registered under the REACH Regulation but is not currently being manufactured in and / or imported to the European Economic Area.


Allyl Acetoacetate is an adhesion promoter.
Allyl Acetoacetate is available in colorless to pale yellow colored liquid form.
Allyl Acetoacetate is recommended for coatings.


Allyl Acetoacetate holds significant importance as an organic compound widely utilized in chemical synthesis and scientific exploration.
As a colorless liquid with a potent fragrance, Allyl Acetoacetate effortlessly dissolves in various organic solvents.
Its versatility in the synthesis of numerous compounds makes Allyl Acetoacetate a valuable asset.



USES and APPLICATIONS of ALLYL ACETOACETATE:
Allyl Acetoacetate is also used as a cross-linking agent for polyvinyl chloride plastics.
Allyl Acetoacetate is used in the formulation of pharmaceuticals and as an intermediate for fine chemicals.
Allyl Acetoacetate is used in formulation or re-packing.


Release to the environment of Allyl Acetoacetate can occur from industrial use: formulation of mixtures.
Moreover, Allyl Acetoacetate plays a role in the creation of polymers, dyes, and catalysts.
Fascinatingly, Allyl Acetoacetate finds application in the synthesis of essential biochemicals, such as vitamins, hormones, and enzymes.


In scientific research, particularly in organic synthesis, Allyl Acetoacetate is highly regarded and employed.
The reaction involving allyl alcohol and acetic anhydride in the presence of a catalyst results in Allyl Acetoacetate as one of the primary products, along with acetic acid.


For this reaction, an inert atmosphere and a temperature of around 100°C are typically maintained.
The outcome of this process serves as a pivotal intermediate for a diverse range of compounds, making Allyl Acetoacetate an indispensable component in various scientific and industrial endeavors.



PHYSICAL and CHEMICAL PROPERTIES of ALLYL ACETOACETATE:
Solubility: 48 g/l (20 °C)
Molar Mass: 142.15 g/mol
Boiling Point: 87 - 91 °C (13 hPa)
Vapor Pressure: 0.2 hPa (20 °C)
Flash Point: 67 °C
Refractive Index: 1.438 (25 °C, 589 nm)
Explosion Limit: 1.15 %(V)
Density: 1.038 g/cm3 (20 °C)
pH: 3.7 (48 g/l, H2O, 20 °C)
Ignition Point: 300 °C
Chemical Name or Material: Allyl Acetoacetate
Melting Point: -85°C
Boiling Point: 195°C

MDL Number: MFCD00009811
CAS: 1118-84-9
Molecular Weight (g/mol): 142.154
InChI Key: AXLMPTNTPOWPLT-UHFFFAOYSA-N
PubChem CID: 70701
SMILES: CC(=O)CC(=O)OCC=C
UN Number: 2810
InChI Key: AXLMPTNTPOWPLT-UHFFFAOYSA-N
IUPAC Name: prop-2-enyl 3-oxobutanoate
PubChem CID: 70701
Percent Purity: ≥95.0% (GC)
SMILES: CC(=O)CC(=O)OCC=C
Molecular Weight (g/mol): 142.154

Formula Weight: 142.15
Physical Form: Liquid
Density: 1.0±0.1 g/cm3
Boiling Point: 192.0±15.0 °C at 760 mmHg
Melting Point: -70 °C
Molecular Formula: C7H10O3
Molecular Weight: 142.152
Flash Point: 75.6±0.0 °C
Exact Mass: 142.062988
PSA: 43.37000
LogP: 1.07
Vapour Pressure: 0.5±0.4 mmHg at 25°C
Index of Refraction: 1.429

Water Solubility: 50 g/L (20 ºC)
Molecular Weight: 142.15 g/mol
XLogP3-AA: 0.6
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 5
Exact Mass: 142.062994177 g/mol
Monoisotopic Mass: 142.062994177 g/mol
Topological Polar Surface Area: 43.4Ų
Heavy Atom Count: 10
Computed by PubChem
Formal Charge: 0

Computed by PubChem
Complexity: 149
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
CAS number: 1118-84-9
EC number: 214-269-9
Hill Formula: C₇H₁₀O₃
Chemical formula: CH₃COCH₂COOCH₂CH=CH₂
Molar Mass: 142.16 g/mol

HS Code: 2918 30 00
Boiling point: 87 - 91 °C (13 hPa)
Density: 1.037 g/cm3
Explosion limit: 1.15 %(V)
Flash point: 67 °C
Ignition temperature: 300 °C
Melting Point: pH value: 3.7 (48 g/l, H₂O, 20 °C)
Vapor pressure: 1 hPa (20 °C)
Solubility: 48 g/l
Appearance: colorless to pale yellow clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No

Melting Point: -85.00 °C. @ 760.00 mm Hg
Boiling Point: 196.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.501000 mmHg @ 25.00 °C. (est)
Flash Point: 168.00 °F. TCC (75.56 °C.)
logP (o/w): 0.703 (est)
Soluble in:
alcohol
water, 6.089e+004 mg/L @ 25 °C (est)
Insoluble in: water
Physical state: liquid
Color: colorless

Odor: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: 194 - 195 °C at 983 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: Lower explosion limit: 1,15 %(V)
Flash point: 67 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity:
Viscosity, kinematic: No data available,
Viscosity, dynamic: No data available

Water solubility: No data available
Partition coefficient: n-octanol/water: log Pow: 0,339 at 25 °C
Vapor pressure: 1 hPa at 20 °C
Density: 1,037 g/cm3
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Molecular Formula / Molecular Weight: C7H10O3 = 142.15
Physical State (20 deg.C): Liquid
Storage Temperature: Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN: 1118-84-9

Reaxys Registry Number: 1758569
PubChem Substance ID: 87559068
MDL Number: MFCD00009811
CAS: 1118-84-9
Molecular Formula: C7H10O3
Molecular Weight (g/mol): 142.154
MDL Number: MFCD00009811
InChI Key: AXLMPTNTPOWPLT-UHFFFAOYSA-N
Melting Point: -85°C
Boiling Point: 195°C
MDL Number: MFCD00009811
UN Number: 2810
InChI Key: AXLMPTNTPOWPLT-UHFFFAOYSA-N
IUPAC Name: prop-2-enyl 3-oxobutanoate

PubChem CID: 70701
Percent Purity: ≥95.0% (GC)
Chemical Name or Material: Allyl Acetoacetate
SMILES: CC(=O)CC(=O)OCC=C
Molecular Weight (g/mol): 142.154
Formula Weight: 142.15
Physical Form: Liquid
Formula: C₇H₁₀O₃
MW: 142.1525 g/mol
Storage Temperature: Ambient
MDL Number: MFCD00009811

CAS Number: 1118-84-9
EINECS: 214-269-9
UN: 2810
ADR: 6.1,III
CAS Number: 1118-84-9
MDL Number: MFCD00009811
Molecular Formula: C7H10O3
Molecular Weight: 142.15
Purity/Analysis Method: 95.0% (GC)
Form: Clear Liquid
Boiling point (°C): 195

Melting point (°C): -85
Flash Point (°C): 76
Specific Gravity (20/20): 1.04
Formula: C₇H₁₀O₃
MW: 142.1525 g/mol
Boiling Pt: 195 °C
Melting Pt: –85 °C
Density: 1.04 (20 °C)
Flash Pt: 76 °C
MDL Number: MFCD00009811
CAS Number: 1118-84-9
UN: 2810
ADR: 6.1,III



FIRST AID MEASURES of ALLYL ACETOACETATE:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ALLYL ACETOACETATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ALLYL ACETOACETATE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ALLYL ACETOACETATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls.
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 120 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A (acc. to DIN 3181)
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ALLYL ACETOACETATE:
-Precautions for safe handling:
*Advice on protection against fire and explosion:
Take precautionary measures against static discharge.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Protected from light.
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of ALLYL ACETOACETATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available


ALLYL ACETOACETATE
Allyl Acetoacetate is an organic compound that is the simplest member of the acetic acid esters.
Allyl Acetoacetate can be synthesized by reacting allyl alcohol with hydrochloric acid and a particle.
Allyl Acetoacetate has been shown to have cytotoxic effects on cardiac tissues, as well as certain reactive properties, which may be due to its ability to form cross-links with proteins.

CAS: 1118-84-9
MF: C7H10O3
MW: 142.15
EINECS: 214-269-9

Synonyms
3-oxo-butanoicaci2-propenylester;Allyl 3-oxobutanoate;Allyl acetylacetate;ACETOACETIC ACID ALLYL ESTER;AC-ALLYL;ALLYL ACETOACETATE;(2-PROPENYL) 3-OXOBUTANOATE;2-PROPENYL ACETOACETATE;Allyl acetoacetate;1118-84-9;Allyl 3-oxobutanoate;Allylacetoacetate;(2-Propenyl) 3-oxobutanoate;Allyl acetylacetate;Acetoacetic acid, allyl ester;Butanoic acid, 3-oxo-, 2-propenyl ester;prop-2-en-1-yl 3-oxobutanoate;prop-2-enyl 3-oxobutanoate;Acetoacetic Acid Allyl Ester;(2-Propenyl)3-oxobutanoate;8HX066J62P;NSC-24280;2-propenyl acetoacetate;UNII-8HX066J62P;AI3-04977;allyl aceto-acetate;EINECS 214-269-9;Allyl 3-oxobutanoate #;Allyl acetoacetate, 97%;Allyl acetoacetate, 98%;EC 214-269-9;SCHEMBL9513;Acetylacetic acid, allyl ester;3-oxo-butyric acid allyl ester;DTXSID40149740;BCP12037;NSC24280;BBL011433;MFCD00009811;NSC 24280;STL146541;AKOS000120505;CS-W018294;VS-02949;DB-003129;NS00001809;EN300-20951;E75749;J-002655;J-519551;Q27270546;F0001-0255

Allyl Acetoacetate is also used as a cross-linking agent for polyvinyl chloride plastics.
Allyl acetoacetate by Shanghai Deborn is an adhesion promoter.
Allyl Acetoacetate is available in colorless to pale yellow colored liquid form.
Allyl acetoacetate is recommended for coatings.

Allyl Acetoacetate Chemical Properties
Melting point: -70 °C
Boiling point: 194-195 °C737 mm Hg(lit.)
Density: 1.037 g/mL at 25 °C(lit.)
Vapor pressure: 0.2 hPa (20 °C)
Refractive index: n20/D 1.439(lit.)
Fp: 75 °C
Storage temp.: Sealed in dry,2-8°C
Solubility: 48g/l
pka: 10.53±0.46(Predicted)
Form: clear liquid
Color: Colorless to Light yellow to Light orange
PH: 3.7 (48g/l, H2O, 20℃)
Explosive limit: 1.15%(V)
Water Solubility: 50 g/L (20 ºC)
Sensitive: Air Sensitive
BRN: 1758569
LogP: 0.146 at 27℃
CAS DataBase Reference: 1118-84-9(CAS DataBase Reference)
NIST Chemistry Reference: Butanoic acid, 3-oxo-, 2-propenyl ester(1118-84-9)
Allyl Alcohol
Texanol ester; 2,2,4-Trimethyl-1,3-pentanediolmono(2-methylpropanoate); 2,2,4-Trimethyl-1,3-pentanediol monoisobutyrate; Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol; ácido isobutírico, monoéster con 2,2,4-trimetilpentano-1,3-diol; Acide isobutyrique, monoester avec 2,2,4-triméthylpentane-1,3-diol CAS NO : 25265-77-4
ALMOND OIL
Almond oil is simply the essential oil pressed out from the nut.
Almond oil can be used as a laxative and, in fact, is milder than most laxatives, including castor oil.
Almond oil is said to generally boost the immune system.

CAS Number: 8007-69-0
EC Number: 616-913-8

Synonyms: Almond oil, Almond oil, SWEET, AMYGDALAE OLEUM, SWEET Almond oil, almondoilfromprunusdulcis, expressedalmondoil, oilofsweetalmond, Oils,almond, stavitine, stavitini, Almond oil FROM PRUNUS DULCIS, PH EUR, Amygdalaeoleumvirginale,PhEur., Sweetalmondoil,virgin, Amygdalaeoleumraffinatum,PhEur., Sweetalmondoil,refined/Almondoil,refined, SWEETALMOND(PRUNUSAMYGDALUSDULCIS)OIL, ALMONDOIL,SWEET,NF, Fats and Glyceridicoils, alMond, PRUNUSAMYGDALUSDULCISOIL, Almond oil, sweet, Amygdalae oleum raffinatum, Almond oil sweet (prunis species), Almond oil (Organic), PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL, Almond oil – Cosmetic grade, Almond oil – 100% Pure, 1151-14-0 [RN], 2-(4-Ethylbenzoyl)benzoesäure [German] [ACD/IUPAC Name], 2-(4-Ethylbenzoyl)benzoic acid [ACD/IUPAC Name], Acide 2-(4-éthylbenzoyl)benzoïque [French] [ACD/IUPAC Name], Benzoic acid, 2-(4-ethylbenzoyl)- [ACD/Index Name], [1151-14-0] [RN], 2-(4-Ethyl-benzoyl)-benzoic acid, 2-(4-EthYl-Benzoyl)Benzoic Acid, 2-(4-ethylbenzoyl)benzoic acid (en), 2-(4-ETHYLBENZOYL)BENZOICACID, 2-[(4-ethylphenyl)carbonyl]benzoic acid, 214-566-3 [EINECS], AC1L2F0A, AC1Q2TDY, AC1Q2TE0, AC1Q5UTG, AGN-PC-0JL9YX, atoms 19 bonds 20, Certified Organic Almond, Certified Organic Almond Meal, Certified Organic Almond oil, EINECS 214-566-3, Oprea1_166141, ORTHO-(PARA-ETHYLBENZOYL)BENZOIC ACID, 100-52-7 [RN], 202-860-4 [EINECS], 471223 [Beilstein], Benzaldehyd [German] [ACD/IUPAC Name], Benzaldehyde [ACD/Index Name] [ACD/IUPAC Name], Benzaldéhyde [French] [ACD/IUPAC Name], VHR [WLN], 240 [PubChem CID], Benzenecarbinal, benzenecarbonal, Benzenemethylal, Benzoic acid aldehyde, Benzoic aldehyde, BEZ, Bitter Almond oil, CU4375000 [RTECS], DTXSID8039241 [CompTox], MFCD00801585 [MDL number], Phenylformaldehyde, Phenylmethanal, PS-11959, 苯甲醛 [Chinese], Almond oil, 66YXD4DKO9, Expressed Almond oil, Almond oil (II), Almond oil (MART.), Almond oil (USP-RS), AMYGDALUS COMMUNIS OIL, AMYGDALUS DULCIS OIL, Amygdalae oleum virginale, HSDB 7793, Huile d'amande, OIL, ALMOND, OIL,ALMOND, Oleo de amendoas, Olio di mandorla, PRUNUS AMYGDALUS OIL, PRUNUS COMMUNIS OIL, Stavitine, Stavitini, UNII-66YXD4DKO9

Almond oil that comes from these delicious tree nuts is commonly used as a natural ingredient in skin and hair care, but few people realize that it may also be good for your health.
Almonds are the edible seeds of the Prunus dulcis tree, more commonly known as the almond tree.

Although almonds are commonly referred to as nuts, they’re actually the seeds found at the center of the almond fruit, which closely resembles a peach.
Almonds can be consumed whole, ground into flour and even made into non-dairy milk.

They are very rich in fat, making them a perfect source of oil.
Sweet almonds are the variety typically eaten and used to make foods, oils and cosmetics.

Meanwhile, bitter almonds are believed to have medicinal properties, though they can be toxic if they’re not properly processed.
Moreover, they’re not widely available.

Most of us are aware of the health benefits of eating sweet almonds.
Almond oil has even more health benefits than crunching on the tasty nut.

Almond oil is simply the essential oil pressed out from the nut.
This pure oil has been found to be rich in Vitamin E, monounsaturated fatty acids, proteins, potassium, and zinc, making it not only heart healthy but good for our skin and hair.

Almond oil Information Almonds are not actually nuts, they are drupes.
There are both sweet and bitter almonds.

Bitter almonds are usually not eaten since they contain hydrogen cyanide, a toxin.
They are, however, pressed into bitter Almond oil.

Usually, though, Almond oil is derived from sweet almonds, the kind that are good to snack on.
Native to the Mediterranean and Middle East, the largest producer of almonds in the United States is California.

Today, 75% of the world’s almond supply is produced in California’s Central Valley.
There will be a subtle difference in Almond oil depending on the variety and location where the almond tree is grown.

People with nut allergies should avoid using Almond oil, but the rest of us are wondering how to use Almond oil.
How to Use Almond oil There are many Almond oil uses.

Almond oil can be used to cook with.
Almond oil is chock full of healthy fats that actually help to reduce cholesterol.

Almond oil can be used to cook with.
Almond oil is chock full of healthy fats that actually help to reduce cholesterol.

Cooking with Almond oil is certainly not the only way to use it.
For centuries, Almond oil has been used medicinally.

As mentioned, Ayurvedic practitioners have been using the oil for thousands of years as massage oil.
The oil has been used to treat vascular problems such as spider and varicose veins as well as to treat liver ailments.

Almond oil can be used as a laxative and, in fact, is milder than most laxatives, including castor oil.
Almond oil is said to generally boost the immune system.

The oil is also an anti-inflammatory and analgesic.
Almond oil has been found to possess mild antioxidant properties and can be used topically to improve the skin.

Almond oil is an excellent emollient as well and can be used to treat dry skin.
The oil improves the texture and moisture absorption of hair as well as treating dandruff.

Almond oil also treats chapped lips and purportedly can heal scars and stretch marks.
One caveat regarding the use of this oil on skin or hair is that it’s oily and can cause clogged pores or skin breakouts, so a little goes a long way.

Refined vs Unrefined Almond oil:
After harvesting, almonds are hulled and dried before different methods are used to extract their oil.
Refined Almond oil is extracted from almonds using high-heat processing and chemicals.

This method negatively affects the nutritional value of the oil, as many of the nutrients found in raw Almond oil are destroyed during high-heat or chemical treatments.
While this method results in a less nutritious oil, refined Almond oil can withstand much higher temperatures and is less expensive than the unrefined type, making it a more cost-effective option for consumers.

Unrefined Almond oil is made by pressing raw almonds without the use of high heat or chemical agents.
This low-heat process helps Almond oil retain much of its nutrient content, making unrefined Almond oil a better choice for culinary uses.

Almond oil is extracted from the seed of the almond fruit.
The methods used to produce refined Almond oil destroy certain nutrients.
Thus, unrefined Almond oil is a better choice for culinary purposes.

Almond oil is rich in vitamin E and unsaturated fats.
Adding Almond oil to your diet may promote heart health, aid weight loss and keep blood sugar levels stable.

Almond oil is a versatile fat that can be used as a food or natural beauty product.
Almond oil may promote heart health, stabilize blood sugar levels, prevent free radical damage and help you maintain a healthy weight.

What’s more, the oil makes an excellent moisturizer for both the skin and hair, and it may even help prevent stretch marks and protect your skin from sun damage.
Unrefined Almond oil retains more nutrients than refined Almond oil and is better for culinary uses.

Just make sure you don’t heat it, as doing so will destroy some of its nutrients.
No matter how you choose to use this interesting oil, it makes an excellent addition to both your pantry and vanity.

Nearly half of a dried almond’s weight is oil.
Ripe almonds are pressed to extract the oil with minimal heat.

This unrefined Almond oil protects the nutrients and the flavor of the oil.
High heat and sometimes chemicals are used to create refined Almond oil.

While refined Almond oil is more heat-tolerant, it may lack the nutritional value of unrefined varieties.
Almond oil, which is also called sweet Almond oil, is not the same as bitter Almond oil.

Bitter Almond oil is made from a different variety of almonds.
Almond oil is refined to remove toxins that are naturally present in the skin of the almonds.

There are two main types of Almond oil bitter and sweet and manufacturers make them from different varieties of the Prunus dulcis tree.
This tree is common in Mediterranean countries, and almonds are its seeds.

Manufacturers extract Almond oil by pressing or grinding almonds.
They may use heat or chemical solvents to refine the oil.

Cold-pressed Almond oil is extracted at a low temperature without solvents, and cold-pressed oils may be particularly beneficial for the skin.

Almond oil is an emollient with soothing properties.
Almond oil is the oil of the bitter almond after the removal of hydro- cyanic acid.

Almond oil is a colorless to slightly yellow liquid having a strong principally almond-like aroma.
Almond oil is used mainly in the pharmaceu- tical and cosmetic industry and also as a food flavoring agent.

Almond oil is both a moisturizer and an emollient.
Moisturizers supply water to the skin and hold it in with an oily substance.

Emollients smooth the skin, filling in little gaps.
Rather than adding moisture, they help the skin retain it by improving its barrier function.

Many people use Almond oil to help treat common skin conditions, such as dermatitis and eczema.
In general, there is good evidence that moisturizers improve eczema.

One study showed that a moisturizer containing sweet Almond oil reduced the symptoms of moderate or severe hand dermatitis.

Another showed that emollients containing refined Almond oil helped relieve itching and improved the skin’s barrier function in people with xerotic eczema, also known as asteatotic eczema, which causes the skin to become particularly dry, cracked, and itchy.

Some people with acne use Almond oil as a moisturizer, often alongside topical acne medication.
The Food and Drug Administration (FDA) caution that oil from moisturizers may make acne worse, but some doctors recommend moisturizing.

Almond oil produces kernels (nuts) that are a familiar food.
Almond and its oil, prepared by pressing the kernels, is used to make medicine.

Almond oil contains anti-inflammatory and immunity-boosting properties, both of which are super useful for the colder seasons, as well as cardiovascular benefits that help to improve your body's cholesterol.
Almond oil is rich in vitamin D, vitamin E (Tocopherol) and various minerals that help soothe the skin from irritation, protect the skin from UV radiation damage and restore the skin’s moisture barrier.

Almond oil has been used in Ancient Chinese and Ayurvedic medicine and healing practices for centuries to treat minor wounds, cuts, and abrasions and to prevent scarringi
You can find Almond oil—specifically, sweet Almond oil—in a wide variety of skincare products, thanks to its hydrating, soothing, and smoothing qualities.

Since Almond oil is an emollient, it's excellent for locking in hydration, especially when used as the last step in your skincare routine.
Almond oil is full of antioxidants like vitamins A and E, potassium, and zinc.
It's also great for soothing irritation and improving discoloration.

Cooking with Almond oil:
Your heart will thank you for eating Almond oil.
Full of monounsaturated fatty acids, Almond oil can elevate the levels of “good” cholesterol, or high-density lipoproteins (HDL).

Almond oil can also lower levels of “bad” cholesterol, or low-density lipoproteins (LDL), when it replaces saturated and trans fats.
Almond oil can help reduce the risk of cardiovascular disease because of its high levels of antioxidants, its ability to decrease inflammation in the body, and its effect on cholesterol.

When cooking with Almond oil, remember to keep unrefined or virgin oils at low heat to prevent burning the oil and destroying the nutritional value.
Almond oil is best used for salad dressing, low-heat baking, or as finishing oil on top of a dish to add extra flavor and nutrition.

Its mild flavor makes it perfect for slipping into dishes.
Refined oil can be used for roasting or sautéing because it has been processed to tolerate a much higher heat, up to 420°F (215°C).

Next steps
Though whole almonds will provide the most nutrition, Almond oil can be a healthy addition to your diet.
Whether you’re putting it on your body or on your salad, look for unrefined or virgin Almond oil.

Unrefined oil retains more of the nutrients that are beneficial for your skin, hair, and health.
If you’re unsure if you have a nut allergy, it’s best to get tested first before eating Almond oil or using it on your body.

If you don’t think you’re allergic, try a test small test patch of the oil on the inside of your wrist before using it in your skin care routine.

Applications of Almond oil:

Pharmaceutical Applications:
Almond oil is used therapeutically as an emollientand to soften ear wax.
It is uses as a pharmaceutical excipient it is employed as a vehicle in parenteral preparations, such as oily phenol injection.

Almond oil is also used in nasal spray, and topical preparations.
Almond oil is also consumed as a food substance.

Uses of Almond oil:
Almond oil is a multipurpose product that can be used as both a food and natural skin and hair care product.

Almond oil can be applied directly to the skin by massaging it.
It may help to rub Almond oil between your palms or fingertips first to warm it up.

Almond oil is serves as an emollient and a carrier, providing an elegant skin feel and promoting spreadability in creams, lotions, and bath oils.
Almond oil’s main constituent is olein with a small proportion of linoleic acid glyceride.

Almond oil is obtained from sweet almonds that have undergone a cleaning and crushing process, leaving them in powder form.
The powder is then cold-pressed and left to “rest” for one to two weeks.
After the resting period, the Almond oil is filtered and often bleached.

Almond oil is the triglyceride oil (vegetable oil) derived from almonds, and is very similar in composition to olive oil.

For most skin types though, Almond oil is a safe and effective ingredient for repairing the skin barrier and adding protection against dryness and irritation.

Uses for skin:
One of the best things about Almond oil is that you can add it to your routine in so many ways.

1. As makeup remover

Fun fact:
Makeup remover wipes can be a breeding ground for zits—they're known to rub bacteria, irritants, and residue all over your face, which then transfers to your pillow—so I like to use Almond oil instead.
Just pour three to four drops on a cotton pad and gently rub it over your eyelashes and eyelids until it breaks down your makeup.
Follow with your favorite face wash and your skin will be left clean (and soft!) as hell.

2. As an oil cleanser:
Oil cleansing isn't just about makeup removal, btw.
At the end of a long day, rub a couple drops of Almond oil between your palms and gently massage it into your skin before rinsing with water.
The oil will help break down any makeup, grime, or oil hanging out on your face, leaving you with a clean canvas for the rest of your skincare routine.

3. As a sealant:
The hydrating properties of sweet Almond oil make it a great final step in your skincare routine.
After your cleansers, serums, treatments, and moisturizers, pat two to three drops of Almond oil on your face to lock in (and level up) your products.
Pro tip: You can also massage a little Almond oil onto your skin after applying body moisturizer for the same effect.

4. As a cuticle oil:
Dropping a little Almond oil onto your cuticles to boost hydration and soothe irritation.
Repeat regularly (think: once every day) and pair with hand cream to keep your manicure looking and feeling fresh.

In the Kitchen:
Almond oil is a mild, nutty-tasting oil that makes a great addition to many dishes.
Unrefined Almond oil should not be used in cooking, as high temperatures can destroy its nutritional value.

Rather, this type of Almond oil should be treated more as a finishing oil and added to foods after the cooking process is completed.
However, refined Almond oil has a higher smoke point of 420°F (215°C) and can be used for cooking methods like roasting and sautéing.

It’s less expensive and more heat-tolerant than the unrefined kind, as the refinement process destroys much of the nutrients in unrefined Almond oil.

Here are several ways to use unrefined Almond oil:

As a tasty salad dressing:
Combine unrefined Almond oil with apple cider vinegar and chopped herbs.

To add a nutty flavor to meals:
Drizzle Almond oil over your favorite side dish to give it an extra kick.

Over pasta:
Add a bit of Almond oil to your pasta to add a boost of healthy fats.

As Part of Your Beauty Routine:
If you are looking to swap out some of your skin and hair products for more natural, non-toxic options, Almond oil is a great way to go.

Other uses include:
Mixing oil with sugar to make an exfoliating facial scrub
Mixing with salt to make a body scrub
Adding a few tablespoons to a warm bath
Applying oil to chapped lips
Applying to nails and cuticles

Almond oil Nutrition:
Although Almond oil is not as rich in nutrients as whole almonds, it has nutritional benefits.

Nutritional Breakdown:
Below is the nutritional breakdown of 1 tablespoon (14 grams) of Almond oil.

Calories: 119
Total fat: 13.5 grams
Saturated fat: 1.1 grams
Monounsaturated fat: 9.4 grams
Polyunsaturated fat: 2.3 grams
Vitamin E: 26% of the RDI
Phytosterols: 35.9 mg

Almond oil is an excellent source of vitamin E and contains a small amount of vitamin K.
Most of the health benefits related to Almond oil stem from its high amount of healthy fats.

Fatty Acid Breakdown:

Here are the proportions of fatty acids found in Almond oil:
Monounsaturated fat: 70%
Polyunsaturated fat: 20%
Saturated fat: 10%

A diet rich in unsaturated fats has been linked to many health benefits, including a reduced risk of heart disease and obesity.
What’s more, monounsaturated fats may help lower high blood pressure, a risk factor for heart disease.

Diets high in monounsaturated fats have also been linked to a lower risk of certain cancers like endometrial cancer, and they may even help you lose weight.
In fact, a recent review of 24 studies including 1,460 people found that a diet high in monounsaturated fats was more effective than a high-carb diet for weight loss.

Almond oil is a good source of the antioxidant vitamin E and unsaturated fats.
Diets rich in unsaturated fat may provide some health benefits, including a reduced risk of heart disease and obesity, and they may aid weight loss.

Benefits of Almond oil:

Potential Health Benefits:
Whole almonds are thought help lower blood pressure and cholesterol levels and aid in weight loss, and Almond oil may be good for your health as well.
In fact, Almond oil has been linked to a wide range of potential health benefits, including lowering the risk of heart disease and stabilizing blood sugar levels.

May Help Keep Your Heart Healthy:
Almond oil consists of 70% monounsaturated fat, which has been researched for its effects on heart health.
Monounsaturated fats have been shown to increase levels of “good” HDL cholesterol.

HDL is a type of protein that carries cholesterol away from the arteries and transports it to the liver, where it is broken down and excreted from the body.
Healthy levels of HDL cholesterol have been shown to help protect against heart disease.

Both almonds and Almond oil have also been shown to lower levels of “bad” LDL cholesterol and total cholesterol.

High levels of LDL cholesterol and total cholesterol are considered risk factors for heart disease.
Lowering these levels can help keep the heart healthy.

High in Antioxidants:
Almond oil is a great source of the potent antioxidant vitamin E.
In fact, 1 tablespoon (15 ml) of this nutty oil delivers 26% of the recommended daily intake.

Vitamin E is a group of eight fat-soluble compounds that have antioxidant properties.
These compounds protect cells from harmful substances called free radicals.

While free radicals are necessary for health, they can cause damage if their numbers grow too high in the body.
Free radical overload leads to oxidative damage and has been linked to a number of chronic diseases, including cancer and heart disease.

Studies have shown that higher intakes of vitamin E can help lower the risk of heart disease, age-related macular degeneration and cognitive decline in the elderly.

May Be Beneficial for Blood Sugar Control:
Adding Almond oil to your diet may help keep your blood sugar stable.

Almond oil is rich in monounsaturated and polyunsaturated fats, both of which have been shown to help lower blood sugar in people with diabetes.
In fact, replacing carbs with unsaturated fats has been shown to lower blood sugar levels and improve insulin resistance and levels of HbA1c, a marker for long-term blood sugar control.

What’s more, the participants who consumed Almond oil felt fuller after their meal, leading them to consume less throughout the day.

May Aid Weight Loss When Paired With a Reduced-Calorie Diet
A diet rich in healthy fats may help you lose weight.
Many people avoid fats when they’re trying to drop pounds, but consuming the right kinds of fats can be beneficial for weight loss.

A diet that includes a healthy amount of whole almonds has been shown to help people shed excess weight.
Likewise, adding Almond oil to your diet may help you lose fat.
Diets rich in monounsaturated and polyunsaturated fats have been shown to decrease body fat and promote weight loss.

Beauty Benefits:
Almond oil is a popular ingredient in natural beauty products.
This mild and soothing oil is beneficial for both the skin and hair.

This is partly thanks to its emollient properties, meaning it helps prevent water loss from the skin.
This quality makes Almond oil an excellent choice to keep the skin, hair and scalp soft and hydrated.

The moisturizing effects of Almond oil may be especially helpful for people who have dry or sensitive skin.
Almond oil is packed with vitamin E, which may help protect the skin from sun damage and premature aging.

This makes using unrefined Almond oil important in skin care as well, as unrefined oil is higher in vitamin E.
What’s more, this soothing oil may even help prevent the spread of stretch marks.

This versatile oil makes a great choice for people looking for natural beauty products that have a limited number of ingredients and can be used in many ways.
Almond oil can function as a gentle makeup remover, a natural skin or hair moisturizer or a velvety massage oil.

Almond oil may help protect the skin from sun damage and prevent stretch marks.
Almond oil can be used in many ways, including as a moisturizer, massage oil or makeup remover.

Almond oil is less expensive than most commercially made moisturizers and doesn’t contain any harmful ingredients.
Furthermore, it’s a multipurpose beauty product that can be used both on the skin and hair.

Below are some ways to add Almond oil to your skin or hair care routine.

As a moisturizer:
Almond oil is a perfect moisturizer for sensitive skin.

Apply it to extra-dry spots:
Rub Almond oil on the elbows, feet and any other areas that tend to get dry.

To make a homemade hair mask:
Make a hydrating hair mask by mixing Almond oil with mashed avocado and then smoothing it on damp hair.

Combine it with essential oils:
Use Almond oil as a carrier oil to dilute essential oils when you’re applying them to the skin.

When using unrefined Almond oil in the kitchen, don’t heat it.
Instead, use it as a finishing oil.
You can also use Almond oil as a beauty product.
Almond oil makes an excellent moisturizer for both the skin and hair.

General Benefits:
Almond oil is full of vitamin E, and it’s a great source of magnesium, phosphorus, and copper.
The antioxidant-rich oil is known for its free radical fighting abilities.
It’s also anti-inflammatory and boosts immunity.

Containing omega-3 fatty acids, Almond oil might help you maintain healthy cholesterol levels and improve your memory.
Almond oil may help lower your risk for diseases like cancer and heart disease.

Benefits for skin:
Almond oil has been used for centuries to soothe the skin and treat minor wounds and cuts.
Almond oil has been used in ancient Chinese and Ayurvedic practices to treat skin conditions like eczema and psoriasis.

More than soothing dry skin, Almond oil can improve complexion and skin tone.
It’s highly emollient, which means it helps to balance the absorption of moisture and water loss.

Because it is antibacterial and full of vitamin A, Almond oil can be used to treat acne.
Its concentration of vitamin E can also help to heal sun damage, reduce the signs of aging, and fade scars.

Almond oil soaks in quickly and is a powerful moisturizer, so it can be used on the face or body. You can apply it straight, or mix it with essential oils to get its benefits.
Beyond moisturizing your skin, Almond oil is a great massage oil or skin treatment.

Almond oil also has powerful antifungal properties.
Rub it on your feet to prevent athlete’s foot or to help remove other fungal infections like ringworm. You can use Almond oil as a cleanser or to gently remove makeup as well.

Reduced Skin Irritation:
Almond oil can be used to calm your skin in times of need.
Whether you're dealing with itchiness and swelling or something more clinical like psoriasis or eczema, Almond oil can soothe the irritation as a quick fix before finding a more permanent solution.
Applying it topically to the areas of need adds an extra dose of moisture, relieving any irritation your skin may be experiencing.

Calms Inflammation:
For acne patients, it is an alternative to harsher ingredients.
Because it not only dissolves excess oil on the face, but also decreases inflammation.

Benefits for hair:
Your skin isn’t the only thing that can benefit from Almond oil.
The nourishing oil can soften and strengthen your hair.

It’s rich in vitamin B-7, or biotin, so Almond oil helps to keep hair and nails healthy and strong.
Almond oil can also help protect your hair from sun damage, with a natural SPF 5.

You can use Almond oil as a scalp treatment.
Its antibacterial and fungicidal properties make it effective at balancing the yeast that causes dandruff.
Almond oil easily soaks into the skin, so Almond oil works well at hydrating the scalp and cleansing the hair follicles.

You can also smooth frizz and heal damaged hair with Almond oil.
Apply a dime-sized amount or less to the ends of your hair before drying to hydrate and decrease frizz.

Possible benefits for the skin:
Almond oil mostly remains at the surface of the skin, so any effects take place there.
Some believe that the oil has antioxidant, anti-inflammatory, antibacterial, or anticarcinogenic properties and that it may help wounds heal.

Stretch marks of pregnancy:
Pregnant women looking to prevent stretch marks or reduce associated itching might try massaging Almond oil into their abdomens.
One study found that massage with bitter Almond oil can reduce stretch marks, but that the application of the oil without massage did not.

Another study indicated that sweet Almond oil cream may reduce the itchiness of stretch marks and their spread.
Overall, the evidence that Almond oil helps with stretch marks is limited, and further research is necessary.

Anti-aging and UV protection:
Almond oil may help reduce signs of aging and restore or support the barrier function of the skin.
Some people also believe that Almond oil may help protect the skin from the damaging effects of ultraviolet radiation, though there is very limited evidence for this.
Instead, the Centers for Disease Control and Prevention (CDC) recommend covering the skin when outdoors, staying in the shade, and using sunscreen.

Circles under the eyes and skin lightening:
Some people rub Almond oil under their eyes to reduce bags or dark circles.
There is little reliable scientific evidence for this or for Almond oil helping to lighten patches of darker skin.

Lighten dark circles and reduces under eye puffiness:
This is due to Almond oils anti-inflammatory properties, helping skin to look brighter and fresher.

Relieve dark spots, eczema & rashes:
Almond oil contains emollient properties, which makes it an excellent substance for improving both complexion and skin tone.

Natural makeup remover:
Almond oil glides smoothly onto the skin and is a lightweight ingredient that doesn't leave residue, making it excellent for gently removing makeup from your face.
Deeply moisturises dry skin whilst also being gentle on sensitive skin.

Minimises stretch marks:
Almond oil for skin does this much the same way it helps to relieve acne scarring and dark spots.
Almond oil for skin has excellent softening properties which allows the skin to stretch without magnifying these marks.

Skin rejuvenation:
Almond oil for skin helps to even out skin tone and improve complexion if used frequently.

Handling and Storage of Almond oil:

Precautions for safe handling:
No special measures are necessary.

Advice on general occupational hygiene:
Keep away from food, drink and animal feedingstuffs.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed.

Incompatible substances or mixtures:
Observe hints for combined storage.

Consideration of other advice:

Specific designs for storage rooms or vessels:
Recommended storage temperature: 15–25 °C

Specific end use(s):
No information available.

Stability and Reactivity of Almond oil:

Reactivity:
This material is not reactive under normal ambient conditions.

If heated:
Vapours may form explosive mixtures with air.

Chemical stability:
The material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.

Possibility of hazardous reactions:
Violent reaction with: strong oxidiser

Conditions to avoid:
There are no specific conditions known which have to be avoided.

Incompatible materials:
There is no additional information.

First aid measures of Almond oil:

General notes:
No special measures are necessary.

Following inhalation:
Provide fresh air.

Following skin contact:
Rinse skin with water/shower.

Following eye contact:
Rinse cautiously with water for several minutes.

Following ingestion:
Rinse mouth.
Call a doctor if you feel unwell.

Most important symptoms and effects, both acute and delayed:
Symptoms and effects are not known to date.

Indication of any immediate medical attention and special treatment needed:
none

Firefighting measures of Almond oil:

Suitable extinguishing media:
co-ordinate firefighting measures to the fire surroundings
water spray, dry extinguishing powder, BC-powder, carbon dioxide (CO₂)

Unsuitable extinguishing media:
water jet

Special hazards arising from the substance or mixture:
Combustible.

Hazardous combustion products:
Carbon monoxide (CO), Carbon dioxide (CO₂), May produce toxic fumes of carbon monoxide if burning.

Advice for firefighters:
In case of fire and/or explosion do not breathe fumes.
Fight fire with normal precautions from a reasonable distance.
Wear self-contained breathing apparatus.

Accidental release measures of Almond oil:

Personal precautions, protective equipment and emergency procedures:

For non-emergency personnel:
No special measures are necessary.

Environmental precautions:
Keep away from drains, surface and ground water.

Methods and material for containment and cleaning up:

Advice on how to contain a spill:
Covering of drains.

Other information relating to spills and releases:
Place in appropriate containers for disposal.
Ventilate affected area.

Names of Almond oil:

Regulatory process names:
Oils, almond

IUPAC names:
Almond oil
Oils, almond

Other names:
Almond oil
Prunus amygdalus dulcis oil

Other identifiers:
8007-69-0
ALMOND OIL
ALMOND OIL Are There Benefits to Using Almond Oil on Your Face? Ancient Chinese and Ayurvedic practices have used almond oil for centuries to help soothe and soften the skin and to treat minor wounds and cuts. Today, it’s not uncommon to find almond oil in a wide variety of cosmetic and beauty products. In this article, we’ll take a closer look at the benefits of almond oil and the ways it can be used on your skin. What nutrients does almond oil have? There are two types of almond oil: sweet and bitter. Sweet almond oil is the kind that’s better suited to your skin. It contains the following nutrients: What are the benefits of using almond oil on your face? Although there’s plenty of research that touts the benefits of eating almondsTrusted Source, there’s less scientific evidence on the benefits of using almond oil on the skin. However, according to some clinical studies and anecdotal evidence, applying almond oil to the skin may have the following benefits: Reduces puffiness and under-eye circles. Because almond oil is an anti-inflammatoryTrusted Source, it may help ease swelling of the skin. Improves complexion and skin tone. Due to its emollient propertiesTrusted Source, almond oil has the potential to improve both complexion and skin tone. Treats dry skin. Almond oil has been used for centuries to treat dry skin conditions, including eczema and psoriasis. Helps reverse sun damage. Animal studiesTrusted Source have shown that vitamin E, one of the nutrients in almond oil, may help reduce damage to the skin caused by UV exposure. Reduces the appearance of scars. In ancient Chinese and Ayurvedic medicine, almond oil was used to reduce scarringTrusted Source. The vitamin E content may contribute to helping smooth the skin. Reduces the appearance of stretch marks. According to a 2016 study, sweet almond oil may be an effective treatment for preventing and reducing stretch marks. Is it safe to use almond oil on your skin? Almond oil is generally considered safe to use on your skin. However, there are some safety precautions to keep in mind. If you’re allergic to nuts, avoid using almond oil on your skin. If you’ve never used almond oil on your skin before, do a patch test before applying to your face. You can do a patch test by dabbing a small amount of almond oil on the inside of your wrist or elbow. If there are no signs of redness, itching, burning, or swelling within a few hours, the oil is likely safe to use on your skin. How to use almond oil? There are a few different ways to use almond oil on your face. Almond oil can also be used in a cleanser or moisturizer. Almond oil is known as a carrier oil, which means it has the ability to carry other essential oils more deeply into the skin. You can mix almond oil with an essential oil that’s known to benefit the skin, like rosehip, lavender, rose geranium, or lemon oil. Be sure to patch test the essential oil on the inside of your elbow or wrist before applying to your face. Add a few drops of the essential oil to each ounce of almond oil and mix well. Apply the oil mixture to damp skin and rinse with warm water. Because it’s an oil cleanser, you may need to rinse twice to remove any residue. As a moisturizer You can also use almond oil as a moisturizing oil. To do so, wash and dry your skin as usual. Then, gently pat a small amount of almond oil — about half the size of a dime — onto your face with your fingertips, and let it absorb into your skin. If you’re using it as a moisturizer, you don’t need to rinse it off. The bottom line Almond oil has been used for thousands of years to soothe, soften, and repair the skin. Due to its anti-inflammatory and emollient properties, as well as its high nutrient content, it’s still a popular skin care ingredient today. It’s generally considered safe, but if you’re allergic to nuts, don’t use almond oil on your skin. If you’ve never tried almond oil before, do a patch test before applying it to your face. If you’re unsure if almond oil is right for your skin, talk to your doctor or dermatologist before using it. Health Benefits and Uses of Almond Oil This article uncovers how almond oil may benefit your health and how it can be used as a multipurpose, non-toxic beauty treatment. What Is Almond Oil? Refined vs Unrefined Almond Oil After harvesting, almonds are hulled and dried before different methods are used to extract their oil. Refined almond oil is extracted from almonds using high-heat processing and chemicals. This method negatively affects the nutritional value of the oil, as many of the nutrients found in raw almond oil are destroyed during high-heat or chemical treatments (1). While this method results in a less nutritious oil, refined almond oil can withstand much higher temperatures and is less expensive than the unrefined type, making it a more cost-effective option for consumers. Unrefined almond oil is made by pressing raw almonds without the use of high heat or chemical agents. This low-heat process helps almond oil retain much of its nutrient content, making unrefined almond oil a better choice for culinary uses. SUMMARY Almond oil is extracted from the seed of the almond fruit. The methods used to produce refined almond oil destroy certain nutrients. Thus, unrefined almond oil is a better choice for culinary purposes. Almond Oil Nutrition Although almond oil is not as rich in nutrients as whole almonds, it has nutritional benefits. Nutritional Breakdown Below is the nutritional breakdown of 1 tablespoon (14 grams) of almond oil (2). Most of the health benefits related to almond oil stem from its high amount of healthy fats. Fatty Acid Breakdown Here are the proportions of fatty acids found in almond oil: SUMMARY Almond oil is a good source of the antioxidant vitamin E and unsaturated fats. Diets rich in unsaturated fat may provide some health benefits, including a reduced risk of heart disease and obesity, and they may aid weight loss. Potential Health Benefits of Almond Oil Whole almonds are thought help lower blood pressure and cholesterol levels and aid in weight loss, and almond oil may be good for your health as well. In fact, almond oil has been linked to a wide range of potential health benefits, including lowering the risk of heart disease and stabilizing blood sugar levels (10, 11Trusted Source, 12Trusted Source). May Help Keep Your Heart Healthy Almond oil consists of 70% monounsaturated fat, which has been researched for its effects on heart health. Both almonds and almond oil have also been shown to lower levels of “bad” LDL cholesterol and total cholesterol (14Trusted Source). In one small study, a diet rich in almond oil significantly lowered both LDL and total cholesterol levels, while raising HDL cholesterol by 6% (15). High in Antioxidants Almond oil is a great source of the potent antioxidant vitamin E. Adding almond oil to your diet may help keep your blood sugar stable. In one study, participants who consumed a breakfast with added almond oil had lower blood sugar, both after the meal and throughout the day, compared to participants who did not eat almond oil (22Trusted Source). What’s more, the participants who consumed almond oil felt fuller after their meal, leading them to consume less throughout the day. A diet that includes a healthy amount of whole almonds has been shown to help people shed excess weight. Likewise, adding almond oil to your diet may help you lose fat. SUMMARY Almond oil is rich in vitamin E and unsaturated fats. Adding almond oil to your diet may promote heart health, aid weight loss and keep blood sugar levels stable. Almond Oil Beauty Benefits Almond oil is a popular ingredient in natural beauty products. This mild and soothing oil is beneficial for both the skin and hair. This quality makes almond oil an excellent choice to keep the skin, hair and scalp soft and hydrated (25Trusted Source). The moisturizing effects of almond oil may be especially helpful for people who have dry or sensitive skin. Almond oil is packed with vitamin E, which may help protect the skin from sun damage and premature aging. SUMMARY Almond oil may help protect the skin from sun damage and prevent stretch marks. It can be used in many ways, including as a moisturizer, massage oil or makeup remover. How to Use Almond Oil Almond oil is a multipurpose product that can be used as both a food and natural skin and hair care product. In the Kitchen Almond oil is a mild, nutty-tasting oil that makes a great addition to many dishes. Unrefined almond oil should not be used in cooking, as high temperatures can destroy its nutritional value. Rather, this type of almond oil should be treated more as a finishing oil and added to foods after the cooking process is completed. However, refined almond oil has a higher smoke point of 420°F (215°C) and can be used for cooking methods like roasting and sautéing. It’s less expensive and more heat-tolerant than the unrefined kind, as the refinement process destroys much of the nutrients in unrefined almond oil. Here are several ways to use unrefined almond oil: As a tasty salad dressing: Combine unrefined almond oil with apple cider vinegar and chopped herbs. To add a nutty flavor to meals: Drizzle almond oil over your favorite side dish to give it an extra kick. Over pasta: Add a bit of almond oil to your pasta to add a boost of healthy fats. As Part of Your Beauty Routine If you are looking to swap out some of your skin and hair products for more natural, non-toxic options, almond oil is a great way to go. Almond oil is less expensive than most commercially made moisturizers and doesn’t contain any harmful ingredients. Furthermore, it’s a multipurpose beauty product that can be used both on the skin and hair. Below are some ways to add almond oil to your skin or hair care routine. As a moisturizer: Almond oil is a perfect moisturizer for sensitive skin. Apply it to extra-dry spots: Rub almond oil on the elbows, feet and any other areas that tend to get dry. To make a homemade hair mask: Make a hydrating hair mask by mixing almond oil with mashed avocado and then smoothing it on damp hair. Combine it with essential oils: Use almond oil as a carrier oil to dilute essential oils when you’re applying them to the skin. SUMMARY When using unrefined almond oil in the kitchen, don’t heat it. Instead, use it as a finishing oil. You can also use almond oil as a beauty product. It makes an excellent moisturizer for both the skin and hair. The Bottom Line Almond oil is a versatile fat that can be used as a food or natural beauty product. Almond oil may promote heart health, stabilize blood sugar levels, prevent free radical damage and help you maintain a healthy weight. Unrefined almond oil retains more nutrients than refined almond oil and is better for culinary uses. Just make sure you don’t heat it, as doing so will destroy some of its nutrients.. People can use almond oil to moisturize the skin and help treat conditions such as eczema. In this article, we look at how almond oil is made, the evidence of its benefits to the skin, and the risk of side effects. What is almond oil? There is little direct evidence that almond oil benefits the skin. There are two main types of almond oil — bitter and sweet — and manufacturers make them from different varieties of the Prunus dulcis tree. This tree is common in Mediterranean countries, and almonds are its seeds. Manufacturers extract almond oil by pressing or grinding almonds. They may use heat or chemical solvents to refine the oil. Cold-pressed almond oil is extracted at a low temperature without solvents, and cold-pressed oils may be particularly beneficial for the skin. Possible benefits of almond oil for the skin Almond oil mostly remains at the surface of the skin, so any effects take place there. Below, we describe common uses of almond oil on the skin and what researchers have to say. Dermatitis, eczema, or dry skin Almond oil is both a moisturizer and an emollient. Many people use almond oil to help treat common skin conditions, such as dermatitis and eczema. In general, there is good evidence that moisturizers improve eczema. One study showed that a moisturizer containing sweet almond oil reduced the symptoms of moderate or severe hand dermatitis. Another showed that emollients containing refined almond oil helped relieve itching and improved the skin’s barrier function in people with xerotic eczema, also known as asteatotic eczema, which causes the skin to become particularly dry, cracked, and itchy. Some people with acne use almond oil as a moisturizer, often alongside topical acne medication. The Food and Drug Administration (FDA) caution that oil from moisturizers may make acne worse, but some doctors recommend moisturizing. Stretch marks of pregnancy Pregnant women looking to prevent stretch marks or reduce associated itching might try massaging almond oil into their abdomens. One study found that massage with bitter almond oil can reduce stretch marks, but that the application of the oil without massage did not. Another study indicated that sweet almond oil cream may reduce the itchiness of stretch marks and their spread. Overall, the evidence that almond oil helps with stretch marks is limited, and further research is necessary. Anti-aging and UV protection Almond oil may help reduce signs of aging and restore or support the barrier function of the skin. Some people also believe that almond oil may help protect the skin from the damaging effects of ultraviolet radiation, though there is very limited evidence for this. Instead, the Centers for Disease Control and Prevention (CDC) recommend covering the skin when outdoors, staying in the shade, and using sunscreen. Circles under the eyes and skin lightening Some people rub almond oil under their eyes to reduce bags or dark circles. There is little reliable scientific evidence for this or for almond oil helping to lighten patches of darker skin. There are few known risks associated with using almond oil on the skin. First, it is a good idea to perform a patch test on a small area to check for an adverse reaction. People with sensitive skin should perform the test over several days to give the body more time to respond. Anyone with a nut allergy should not use almond oil. Also, having eczema can increase the likelihood of having allergies, so people with eczema may want to be extra careful when trying almond oil. One study linked preterm delivery to the daily application of almond oil during pregnancy. However, confirming this risk will require further research. Summary Although people have been using almond oil on the skin for a long time, there is very little evidence that it works better than any other moisturizer or emollient in most cases. Moisturizers and emollients can help relieve many skin conditions, and the choice of almond oil is often down to personal preference. A range of almond oil products is available for purchase online. 10 Health Benefits of Almond Oil Share Pin It The oils you stock in your pantry fill a variety of cooking needs. Whether you are sautéing onions in olive oil or adding almond oil to cookies, oil is an indispensable kitchen staple. Olive and nut oils are versatile and neutral, making them a common choice for everyday use. However you use oil in your kitchen, you likely understand its importance and feel its absence when you run out. What you may not realize are the amazing health benefits some of these oils have. Almond oil, in particular, packs a collection of health benefits when incorporated into your diet and beauty routine. If you have yet to try almond oil, there are quite a few reasons to consider switching. What Is Almond Oil? As its name suggests, almond oil is extracted from almond nuts. The characteristics of an almond oil vary depending on the way it is extracted, processed and the type of almonds used. Almond Oil Extraction There are two common methods used to make almond oil: chemical extraction or expeller pressed. Though chemical extraction produces the highest oil yield, it does so at the sacrifice of the almond oil’s taste, quality and nutrients. Expeller-pressed methods produce higher quality products because they allow the oils to maintain their physical and chemical properties better. As a consumer, choosing an expeller-pressed oil can help ensure you are making the most of the nutritional and quality benefits available. After extraction, some almond oils undergo additional processing to make them “refined.” These steps utilize high temperatures, high pressures, chemicals and deodorization measures to give the almond oil several advantages, including the following: The oil is tasteless. The oil has a higher smoke point than unrefined oils. The oil maintains its nutrient content. Unrefined oils, like a roasted almond oil, do not undergo these processing steps. As a result, they maintain lower smoke points and more full-bodied flavors. Both refined and unrefined almond oil can be beneficial for health applications depending on the taste and smoke point you need. Sweet vs. Bitter Almond Oil It is important to note that almond oils made for consumption are considered sweet almond oils. A type of oil known as bitter almond oil can be made from a different type of almond. Bitter almond oil is sometimes used in soap and massage therapy, but it has toxic properties when ingested. All of the almond oil benefits we describe are based on sweet almond oil. Health Benefits of Almond Oil Almond oil offers health benefits, both internally with a healthy diet and externally with a topical beauty routine. Whether you cook with almond oil or use it on your hair and skin, here are some the benefits you may see: Vitamin E is essential to help your body function well, and almond oil is a great way to add it to your diet. In fact, just one tablespoon of almond oil contains 27 percent of your recommended daily vitamin E intake. When you utilize almond oil in your cooking, you can help protect and nourish your body with powerful vitamin E. Studies show that the monounsaturated fats in almond oil can help stabilize blood sugar in adults with type 2 diabetes. Making simple diet changes like adding almond oil to your cooking, can help keep your blood sugar stable and healthy.. Monounsaturated fats like those in almond oil support several important functions, including: 5. Moisturizing Properties When applied to the skin, almond oil has emollient properties. These properties allow almond oil to soften and smooth skin over time. Accordingly, many bath oil, lipstick and skin cleansing products include almond oil to help moisturize your skin. Using products with almond oil as an ingredient or applying the oil directly to your skin can support smooth and supple skin. Because of its moisturizing properties, almond oil has also been used to treat dry skin conditions like eczema and psoriasis for centuries. Common topical treatments for these conditions include steroid creams, which have concerning long-term side effects. Many have turned to almond oil as a natural supplemental solution. The fatty acids in almond oil help to repair the skin’s natural barrier, lock in more moisture and reduce irritation. Regardless of your skin type, incorporating almond oil into your skin routine can help increase moisture and improve your skin’s appearance. Here are some simple ways to use almond oil for your skin: Sweet almond oil scrub: Combine two tablespoons of sweet almond oil with one tablespoon of white sugar to make a quick and simple exfoliating scrub. To use, massage the scrub into your skin with some warm water and rinse. Sweet almond massage oil: Mix sweet almond oil with a few drops of lavender essential oil and massage into the skin. Sweet almond lotion boost: To enhance your lotion’s moisturizing properties, add a few drops of almond oil to the bottle and use normally. Sweet almond under-eye treatment: Gently massage a few drops of sweet almond oil underneath your eyes to help soften and moisturize the area. 6. Increased Hair Health Using almond oil for your hair provides advantages for both hair appearance and hair health. When incorporated into a shampoo, almond oil helps give hair a natural sheen. At a cellular level, almond oil works to fill gaps in your hair, which contributes to smoother and softer hair over time. Though scientific studies have not confirmed that you can use almond oil for hair growth, it may still help your hair grow longer and stronger. Nut oils like almond oil help to lubricate your hair and protect it from breakage or split ends. In addition to this, the Mayo Clinic reports your diet and vitamin intake are major contributing factors to healthy hair. Consuming almond oil and incorporating it into your hair care can provide several of the necessary ingredients for hair growth. In more ways than one, almond oil can help you set yourself up for healthy hair growth success. Studies have shown that topical almond oil application can help prevent skin damage caused by UV radiation and help slow the aging process. Almond oil can help protect your cells by reducing DNA damage from UV rays and prevent the chemical and structural changes they can make. Applying almond oil to your face and body in tandem with sunscreen can help prevent sun damage and premature aging to keep your skin looking its best. Almond oil can aid with stretch marks in more than one way. Studies have shown that almond oil can both prevent stretch marks in pregnant women as well as reduce itching experienced from stretch marks. Applying almond oil topically can help improve your skin’s elasticity and keep it well-hydrated. This can be especially helpful in preventing stretch marks during the rapid growth in the later trimesters of pregnancy. Though no treatment can fully prevent stretch marks, almond oil can provide vital moisture to help your skin adapt through major changes. Almond oil can be a safe and simple solution to help remove excess earwax build-up. Warm up a few drops of almond oil to help soften earwax and dislodge it from the ear. While there are other influential factors behind acne, almond oil is equipped to fight both inflammation and vitamin deficiency. Its anti-inflammatory and antioxidant properties may help reduce inflammation, boost antioxidant levels and address scarring. Using almond oil for acne may provide a natural remedy to help calm and smooth your skin. Incorporating almond oil into your diet and beauty regime can provide numerous health benefits. When it comes to maximizing benefits, not all almond oils are the same. The production process used and ingredient quality can make all the difference. DIY COSMETICS – ALMOND OIL, THE VITAMIN SPA TREATMENT FOR YOUR SKIN SO WHAT IS ALMOND OIL EXACTLY? Almond oil is cold pressed from ripe almond fruit. When pressing, it’s important to keep the proportion of bitter almonds low to make sure the oil tastes good afterwards. The chopped almonds are gently cold pressed and filtered several times to obtain clear almond oil. Cold pressing is important because heat would destroy the valuable nutrients instantly. You can also buy refined or extracted almond oil, which are cheaper but contain less nutrients. Almonds on table WHY DOES MY SKIN NEED ALMOND OIL? The high level of oleic acid in almond oil is very good for skin. It keeps it supple and acts as a moisturizer. In addition to valuable fatty acids, almond oil also contains numerous important vitamins and minerals in a combination that promotes smooth skin and helps to protect and renew skin cells. Almond oil has a fragrance that is stimulating without being overpowering. Almond oil has a low UV protection factor, but will protect you on the first sunny days of spring. ALMOND SKIN – HOW TO MIX YOUR OWN ALMOND OIL FACE CREAM Our face cream boosts vitamin-rich almond oil with aloe vera and coconut oil. Here’s a list of the ingredients and the natural properties they bring to your skin: 1. 12 ml pure, cold pressed almond oil We’ve already outlined why almond oil should be part of your skin care regime; now it’s time for the details. Almond oil is very rich in vitamins A, B, D and E and also contains potassium, magnesium and calcium. It is rich in unsaturated fatty acids and penetrates deep to make your skin feel softer. The 19 percent linoleic acid it contains protects skin from UV radiation, adds moisture and soothes skin. The palmitic acid (saturated fatty acid) supports the skin barrier to protect us from external influences. Almond oil has a very low acidity, making it mild and beneficial for skin (acid-alkali balance). Step 1 – the oil phase Put the coconut oil, jojoba oil, almond oil and Emulsan in a glass. Today's agenda is to bring to spotlight the many benefits of almond oil, apart from it being a good-for-your-hair ingredient. Besides coconut oil, almond oil is also widely used as base or carrier oil by many hair oil manufacturing companies. Pure almond oil is excellent for hair and does wonders to dry and lifeless skin, nourishing it from root to tip. Some of the most noticeable benefits are stated below:1. Almond oil is excellent for treating dandruff and hair damage. 7. Sweet almond oil can also be used in cooking. almond oil 8. Almond oil can also be used to massage the body and facilitate muscle relaxation. almond oil How to Use Almond Oil According to a leading beauty expert Suparna Trikha, "Almond oil is great for dry skin. Massage about a teaspoon of almond oil on the dry areas." A mix of pure castor oil and almond oil is "Almond oil stimulates collagen. It is enriched with vitamin E which makes it great for both skin and hair. Those who have oily skin can use 2-3 drops of almond oil and apply it on their skin once a week. For dry skin I would recommend a few drops of almond oil massaged onto the skin 2-3 times a week. Also note that topical application of almond oil on facial skin should not exceed more than thrice a week as it can clog pores and trigger acne," notes Dr. Deepali Bharadwaj, a Delhi-based dermatologist and beauty expert. A blend of rosewater and almond oil is excellent as a skin nourishment. It can be used as a face and body moisturiser as well. COMMENTSBeauty Tip: Applying almond oil on lashes right before sleeping will make them thicker, shinier and longer. I have realized that a lot of you don’t know what the difference is between sweet almond oil and bitter almond oil. We use both in the making of our products. I wanted to help you understand more about them and how they are different. Because they are indeed very different. Note: The image above shows a vial of sweet almond oil (a fixed oil) on the left and natural benzaldehyde (which can be derived from bitter almond). Edible almonds surround both jars. What is the difference between Sweet Almond oil and Bitter Almond oil? Sweet almond oil is a fixed oil while bitter almond oil is considered an essential oil. Fixed oils are the carrier oils we use as a base oil whereas essential oils are extracts from plant material. We use sweet almond oil in our most delicate products: Our Face Serums. Both Anti- Aging and Susan’s Own each have their own unique blend of essential oils to benefit particular skin types or conditions. They do not smell like Almond at all even though sweet almond oil is used as their base oil. The two oils are very different from a skincare perspective as well. Sweet almond oil is an excellent lubricant and is beneficial for dry, sensitive skin. Often massage therapists and estheticians use sweet almond oil with their clients because it is so easily absorbed. Sweet almond oil is primarily composed of olein and also contains linoleic acid and glucosides. With its high level of protein, vitamins, and minerals it is nourishing and revitalizing. We use it as the carrier oil in our Susan’s Own Face Serum and Anti-aging Face Serum. Sweet almond oil is one of the most versatile, multipurpose skincare oils available. Sweet Almond oil is a fixed oil that is moisturizing and good for dry and sensitive skin. Great for massage and face care. Bitter Almond oil (or natural benzaldehyde) is an essential oil that provides wonderful scent
ALOE VERA
Nom INCI : ALOE VERA CALLUS EXTRACT Ses fonctions (INCI) Antioxydant : Inhibe les réactions favorisées par l'oxygène, évitant ainsi l'oxydation et la rancidité Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau Agent d'entretien de la peau : Maintient la peau en bon état Agent de protection de la peau : Aide à éviter les effets néfastes des facteurs externes sur la peau
Aloe Vera Ekstraktı
Aloe Barbadensis Leaf Extract; extract of the flowers of the aloe, aloe barbadensis, liliaceae; aloe vera flower extract; aloe barbadensis var. chinensis flower extract; aloe chinensis flower extract; barbados aloe flower extract; curacao aloe flower extract; medicinal aloe flower extract; true aloe flower extract; aloe perfoliata var. vera flower extract; aloe vera flower extract; aloe vera var. chinensis flower extract; aloe vulgaris flower extract; urguentine- cactus flower extract; chirukattali flower extract; extract of the flowers of the aloe, aloe barbadensis, liliaceae cas no:85507-69-3
ALOE VERA EXTRACT

Aloe Vera Extract is a natural botanical ingredient derived from the leaves of the Aloe barbadensis plant, known for its soothing, moisturizing, and healing properties.
Aloe Vera Extract is recognized for its ability to hydrate the skin, calm irritation, and support the skin's natural healing processes, making it a popular choice in skincare and personal care formulations.
This versatile extract offers both therapeutic and cosmetic benefits, helping to maintain healthy, smooth, and rejuvenated skin.

CAS Number: 85507-69-3
EC Number: 287-390-8

Synonyms: Aloe Vera Extract, Aloe Barbadensis Leaf Extract, Aloe Extract, Aloe Leaf Extract, Aloe Barbadensis Extract, Aloe Vera Gel Extract, Aloe Moisturizing Extract, Aloe Soothing Extract, Aloe Healing Extract, Aloe Skin Care Active, Aloe Phytoextract, Aloe Vera Phytocomplex, Aloe Vera Bioactive Extract, Aloe Herbal Extract, Aloe Plant Extract, Aloe Vera Gel, Aloe Vera Skin Protector, Aloe Vera Botanical Extract, Aloe Natural Extract



APPLICATIONS


Aloe Vera Extract is extensively used in the formulation of moisturizing creams, providing deep hydration and soothing benefits for dry and sensitive skin.
Aloe Vera Extract is favored in the creation of calming serums, where it helps to reduce redness and irritation while enhancing skin comfort.
Aloe Vera Extract is utilized in the development of face masks, offering intensive hydration and soothing effects that leave the skin feeling refreshed.

Aloe Vera Extract is widely used in the production of after-sun products, providing soothing and moisturizing benefits to sun-exposed skin.
Aloe Vera Extract is employed in the formulation of eye creams, providing gentle hydration and soothing care for the delicate skin around the eyes.
Aloe Vera Extract is essential in the creation of lotions for sensitive skin, offering lightweight hydration and relief from irritation.

Aloe Vera Extract is utilized in the production of anti-inflammatory creams, providing calming and protective benefits to irritated or inflamed skin.
Aloe Vera Extract is a key ingredient in the formulation of anti-redness treatments, offering targeted care that minimizes visible redness and discomfort.
Aloe Vera Extract is used in the creation of hydrating serums, where it enhances skin moisture levels and improves overall skin texture.

Aloe Vera Extract is applied in the formulation of facial mists, offering a quick and refreshing way to hydrate and soothe the skin throughout the day.
Aloe Vera Extract is employed in the production of body lotions, providing all-over hydration and protection for dry and irritated skin.
Aloe Vera Extract is used in the development of calming creams, providing deep relief and hydration for sensitive and reactive skin.

Aloe Vera Extract is widely utilized in the formulation of scalp treatments, providing hydration and soothing care that supports scalp health and comfort.
Aloe Vera Extract is a key component in the creation of prebiotic skincare products, supporting the skin’s microbiome while providing hydration and soothing benefits.
Aloe Vera Extract is used in the production of lip care products, providing hydration and protection for soft, smooth lips.

Aloe Vera Extract is employed in the formulation of hand creams, offering hydration and soothing care that helps to maintain skin softness and reduce irritation.
Aloe Vera Extract is applied in the creation of daily wear creams, offering balanced hydration and protection for everyday use.
Aloe Vera Extract is utilized in the development of skin repair treatments, providing intensive care that helps to restore and protect damaged or irritated skin.

Aloe Vera Extract is found in the formulation of facial oils, offering nourishing care that supports skin health and reduces sensitivity.
Aloe Vera Extract is used in the production of soothing gels, providing instant relief from irritation and helping to calm reactive skin.
Aloe Vera Extract is a key ingredient in the creation of multipurpose balms, providing versatile care for sensitive areas such as lips, hands, and face.

Aloe Vera Extract is widely used in the formulation of anti-inflammatory skincare products, offering soothing and protective benefits for sensitive skin.
Aloe Vera Extract is employed in the development of nourishing body butters, offering rich hydration and protection for dry, rough skin.
Aloe Vera Extract is applied in the production of anti-aging serums, offering deep hydration and soothing care that helps to maintain youthful-looking skin.

Aloe Vera Extract is utilized in the creation of facial oils, offering nourishing care that supports skin health and reduces oxidative stress.
Aloe Vera Extract is found in the formulation of sensitive skin repair treatments, providing targeted care for areas prone to irritation and discomfort.
Aloe Vera Extract is used in the production of sun care products, providing hydration and soothing care that preserves skin health.



DESCRIPTION


Aloe Vera Extract is a natural botanical ingredient derived from the leaves of the Aloe barbadensis plant, known for its soothing, moisturizing, and healing properties.
Aloe Vera Extract is recognized for its ability to hydrate the skin, calm irritation, and support the skin's natural healing processes, making it a popular choice in skincare and personal care formulations.

Aloe Vera Extract offers additional benefits such as improving skin texture and promoting a healthy skin barrier, ensuring long-lasting comfort and protection.
Aloe Vera Extract is often incorporated into formulations designed to provide comprehensive care for sensitive and dry skin, offering both immediate and long-term benefits.
Aloe Vera Extract is recognized for its ability to enhance the overall health and appearance of the skin, leaving it smooth, hydrated, and radiant.

Aloe Vera Extract is commonly used in both traditional and innovative skincare formulations, providing a reliable solution for maintaining healthy, hydrated skin.
Aloe Vera Extract is valued for its ability to support the skin's natural moisture balance, making it a key ingredient in products that aim to protect and soothe the skin.
Aloe Vera Extract is a versatile ingredient that can be used in a variety of products, including creams, lotions, serums, and oils.

Aloe Vera Extract is an ideal choice for products targeting sensitive, dry, and irritated skin, as it provides gentle yet effective hydration and soothing care.
Aloe Vera Extract is known for its compatibility with other skincare actives, allowing it to be easily integrated into multi-functional formulations.
Aloe Vera Extract is often chosen for formulations that require a balance between hydration, protection, and soothing care, ensuring comprehensive skin benefits.

Aloe Vera Extract enhances the overall effectiveness of personal care products by providing deep hydration, soothing relief, and skin protection in one ingredient.
Aloe Vera Extract is a reliable ingredient for creating products that offer a pleasant user experience, with noticeable improvements in skin comfort and moisture levels.
Aloe Vera Extract is an essential component in innovative skincare products that stand out in the market for their performance, safety, and ability to soothe and hydrate the skin.



PROPERTIES


Chemical Formula: N/A (Natural extract)
Common Name: Aloe Vera Extract (Aloe Barbadensis Leaf Extract)
Molecular Structure:
Appearance: Light yellow to brown liquid or gel
Density: Approx. 1.00-1.05 g/cm³ (for liquid extract)
Melting Point: N/A (liquid or gel form)
Solubility: Soluble in water and alcohols; insoluble in oils
Flash Point: >100°C (for liquid extract)
Reactivity: Stable under normal conditions; no known reactivity issues
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store between 15-25°C in a cool, dry place
Vapor Pressure: Low (for liquid extract)



FIRST AID


Inhalation:
If Aloe Vera Extract is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Wash the affected area with soap and water.
If skin irritation persists, seek medical attention.

Eye Contact:
In case of eye contact, flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
If Aloe Vera Extract is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles if handling large quantities.
Use in a well-ventilated area to avoid inhalation of vapors.

Ventilation:
Ensure adequate ventilation when handling large amounts of Aloe Vera Extract to control airborne concentrations below occupational exposure limits.

Avoidance:
Avoid direct contact with eyes and prolonged skin contact.
Do not eat, drink, or smoke while handling Aloe Vera Extract.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Contain spills to prevent further release and minimize exposure.
Absorb with inert material (e.g., sand, vermiculite) and collect for disposal.
Dispose of in accordance with local regulations.

Storage:
Store Aloe Vera Extract in a cool, dry, well-ventilated area away from incompatible materials (see SDS for specific details).
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and ignition sources.

Handling Cautions:
Avoid inhalation of vapors and direct contact with skin and eyes.
Use explosion-proof equipment in areas where vapors may be present.


Storage:

Temperature:
Store Aloe Vera Extract at temperatures between 15-25°C as recommended by the manufacturer.
Avoid exposure to extreme temperatures.

Containers:
Use approved containers made of compatible materials.
Check for leaks or damage in storage containers regularly.

Separation:
Store Aloe Vera Extract away from incompatible materials, including strong oxidizers.

Handling Equipment:
Use dedicated equipment for handling Aloe Vera Extract to avoid cross-contamination.
Ensure all handling equipment is in good condition.

Security Measures:
Restrict access to storage areas.
Follow all applicable local regulations regarding the storage of cosmetic ingredients.

Emergency Response:
Have emergency response equipment and materials readily available, including spill cleanup materials, fire extinguishers, and emergency eyewash stations.
ALPAFLOR ALP-SEBUM
Alpaflor Alp-sebum is an alpine plant organically planted in the Alps - willow orchid extract, high content of flavonoids, macrocyclic tannins, etc.
Alpaflor Alp-sebumcan inhibit the production of pro-inflammatory substances, has excellent soothing and inhibiting sebum secretion effects, and effectively inhibits acne Grows and shrinks pores.


CAS Number: 849775-73-1
INCI Name: Epilobium Fleischeri Flower/Leaf/Stem Extract, Epilobium Fleischeri Extract, Potassium Sorbate, Citric Acid


Alpaflor Alp-sebum is a clear to slightly opalescent, amber to brown colored slightly viscous liquid.
Alpaflor Alp-sebum is readily incorporated into the aqueous phase of a formulation.
Alpaflor Alp-sebum is an alpine plant organically planted in the Alps - willow orchid extract, high content of flavonoids, macrocyclic tannins, etc.


Alpaflor Alp-sebumcan inhibit the production of pro-inflammatory substances, has excellent soothing and inhibiting sebum secretion effects, and effectively inhibits acne Grows and shrinks pores.
Alpaflor Alp-sebum is suitable for oily and oily skin, oil-free essence and gel, oily T-zone skin products, and skin care products for young skin.


Alpaflor Alp-sebum also has ECOCERT, COSMOS and NATRUE certifications. (transparent to slightly foggy, amber to brown slightly viscous liquid - organic plant extract)
Alpaflor Alp-sebum is an extract from the organically cultivated Swiss Alpine plant willowherb (E. fleischeri) for cosmetic application.


This species is rich in both flavanoids and Alpaflor Alp-sebum is preserved with 0.15% potassium sorbate.
Alpaflor Alp-sebum is certified organic by ECOCERT, COSMOS, and NATRUE.
Alpaflor Alp-sebum is a clear to slightly opalescent, amber to brown coloured, slightly viscous liquid with characteristic odour


Alpaflor Alp-sebum is the latest generation registered innovative principle for hair and skin, therefore it also acts on the scalp.
Alpaflor Alp-sebum derives from Epilobium Fleischeri, a plant with an exceptional soothing activity with a particularly high quantity of flavonoid Oenothein B.


These are the key compounds that exhibit sebum-regulating and anti-inflammatory activity.
The stem is about 10-50 cm tall.
The flowers are pink to purple.


Found a lot near the water stream in cold areas or glaciers
From the obvious benefits of flowers, Alpaflor Alp-sebum is an extract that uses advanced innovation to extract flower substances that are a source of natural benefits pure minerals to get a concentrated extract by bringing it as the main ingredient of the seru.


To nourish your pores to tighten reduce oiliness on the face and have a bright, glowing, radiant skin naturally.
Alpaflor Alp-sebum is organically grown according to “Bio Suisse” standards at altitudes of over 1000 m in the Swiss mountains.
This species is rich in flavonoids and oenothein B – compounds that have regulatory and anti-inflammatory activities.


Alpaflor Alp-sebum is an organic prebiotic bioactive delivering sustainable skin mattifying effect with less sebum.
Alpaflor Alp-sebum is sustainable, organic prebiotic to reduce skin oiliness and balance the microbiome.
Alpaflor Alp-sebum is produced from the rare alpine plant Epilobium fleischeri.


Mattifying the skin and reduces effectively sebum production and pore size for a visible skin appearance improvement.
Alpaflor Alp-sebum is certified organic by COSMOS, NATRUE and Fair Trade certified according to the Fair for Life standard.
The CB (Clean Beauty) grade is without preservative.


Alpaflor Alp-sebum extract is a natural multifunctional skin and hair care ingredient with sebum regulating, anti-inflammatory, and antioxidant effects.
Alpaflor Alp-sebum is obtained from a cultivated Alpine plant commonly called willowherb that is rich in flavonoids and polyphenolic compounds like Oenothein B.


Alpaflor Alp-sebum is an alpine plant organically grown in the Alps - willow orchid extract.
Compared with other varieties of willow orchid, this variety has higher content of flavonoids, macrocyclic tannins, etc., which can inhibit the production of pro-inflammatory substances and has excellent soothing effect.



USES and APPLICATIONS of ALPAFLOR ALP-SEBUM:
Alpaflor Alp-sebum inhibits the activity of 5-α-reductase, reduces the sebum production and provides visibly mattified skin.
Alpaflor Alp-sebum reduces spots for clearer skin and helps to solve maskne issue caused by wearing mask.
Moreover, Alpaflor Alp-sebum down-regulates Cutibacterium acnes level to restore skin's healthy appearance.


Alpaflor Alp-sebum is suitable for oily skin, enlarged pores, sensitive skin and acne-prone skin.
Alpaflor Alp-sebum finds applications in formulating skin care products for young skin and oil-free serums & gels.
Alpaflor Alp-sebum is Ecocert, COSMOS, NATRUE & Halal certified, China listed, and complies with fair trade for Life.


Alpaflor Alp-sebum is a plant extract for cosmetic products.
Alpaflor Alp-sebum can be processed either warm (< 60°C) or cold and should be incorporated into the aqueous phase of a cosmetic formulation.
For skin care preparations, the addition of 1 to 3% Alpaflor Alp-sebum is recommended.


Alpaflor Alp-sebum, its Ecocert certified Alpine treatment that specially reduces sebum production and oily appearance of skin as well as the size of pores.
Alpaflor Alp-sebum is specialized in the cultivation and extraction of Swiss alpine plants to produce high quality extracts.
The plants' daily exposure to strong temperature fluctuations and high UV radiation has forced these species to develop efficient protective factors.


Alpaflor Alp-sebum complex (alpine fireweed extract) controls the functioning of the sebaceous glands and reduces skin oiliness, has anti-inflammatory and anti-allergic effects, relieves redness and irritation.
Alpaflor Alp-sebum is a sustainable multifunctional organic prebiotic with microbiome-balancing properties that helps combat excess oil, enlarged pores, skin sensitivity and acne.


Alpaflor Alp-sebum works by blocking the key enzyme 5-α-reductase to regulate hormones such as testosterone and dihydrotestosterone produced by sebaceous glands, which has been shown as the most efficient method to prevent excessive sebum production (the main cause of oily skin).
Studies have shown that this skin active also strongly modulates key bacteria across all facial areas, including downregulation of lipophilic Cutibacterium acnes to help control sebum production and oiliness, giving skin a healthy appearance.


This also provides blemish care by smoothing skin and reducing spots, leading to visibly clearer and cleaner skin.
Cosmetic Uses: skin conditioning
Alpaflor Alp-sebum inhibits the 5a-reductase enzyme, regulating sebum production, reducing the size of pores, and lessening the oily appearance of the skin and scalp.


In addition, Alpaflor Alp-sebum inhibits inflammatory interleukins (IL-1 and IL-8) realize, leaving a potent anti-inflammatory, soothing, and calming action.
Thanks to its high antioxidant content, Alpaflor Alp-sebum scavenges free radicals protecting dermal cell membranes and DNA from damage and preserving the natural beauty and youthfulness of the skin.


Alpaflor Alp-sebum acts as a sebum-regulating and soothing agent.
Alpaflor Alp-sebum is a sustainable, organic prebiotic to reduce skin oiliness and balance the microbiome.
Alpaflor Alp-sebum moderates sebum production, the main cause of oily skin, by inhibiting the key enzyme 5-α-reductase.


New studies show that this skin active not only helps reduce sebum levels but also strongly modulates the key bacteria on all facial areas, restoring skin's healthy appearance.
Thanks to 3D facial color mapping, we can show that sebum distribution is more complex than just the T-zone – which goes to show that when it comes to targeting oily skin, what’s needed is an effective all-rounder ingredient!


It’s demonstrated that the organic skin care active ingredient Alpaflor Alp-sebum helps reduce sebum levels on all facial areas after 4 weeks, leaving skin less oily and more mattified.
Alpaflor Alp-sebum improves skin appearance by controlling sebum secretion and reducing pore size.


Alpaflor Alp-sebum restores the skin’s healthy apperance, reducing spots, for sensitive skin and acne-prone skin.
Alpaflor Alp-sebum can also significantly inhibit 5α‐reductase reductase to achieve the effect of inhibiting sebum secretion, and effectively inhibit acne growth and shrink pores.


Alpaflor Alp-sebum is suitable for oily and oily skin, oil-free essence and gel, oily T-zone skin products , and skin care products for young skin.
Alpaflor Alp-sebum is transparent to slightly foggy, amber to brown slightly viscous liquid - organic plant extracts)


-Cosmetic applications of Alpaflor Alp-sebum:
*Products designed to treat oily and oily appearing, shiny skin
*“Oil free” products and product lines
*T-zone oiliness and combo skin products
*Skin care products for young skin
*Whitening treatments targeting pore size reduction
*Soothing cosmetic products for oily and combo skin
*Natural and/or Organic cosmetic formulations



BENEFITS CLAIMS OF ALPAFLOR ALP-SEBUM:
Anti-Inflammatory, Suitable for Oily Skin, Spot Prevention, Healthy-Looking Skin, Blemish Control, Soothing, Free Radical Scavenging, Restoring, Breakout Clearing, Skin Microbiome Friendly, Prebiotic Effects, Mattifying Effect, Sebum Control, Antioxidant Properties, Smooth Feel, Irritation Reduction, Anti-Acne, Oil Control, Suitable for Sensitive Skin, Balances Skin Microbiota, Purifying, Aesthethic Enhancement, Shine & Radiance



PROPERTIES OF FLOWER EXTRACT, ALPAFLOR ALP-SEBUM:
1.Alpaflor Alp-sebum is an innovation for oily skin care.
Help reduce oiliness on the face.
And reduce various problems caused by oiliness on the face, such as large pores, facial skin does not look clean and bright Skin prone to acne, etc.
2.Alpaflor Alp-sebum reduces the amount of oil production of the sebaceous glands on the face.
3.Alpaflor Alp-sebum reduces the risk of acne caused by the sebaceous glands producing too much oil and reduces the chance of skin irritation from acne Or it could be caused by the sebaceous glands on your face producing too much oil.



BENEFITS AND APPLICATIONS (COSMETIC APPLICATION) OF ALPAFLOR ALP-SEBUM:
*Alpaflor Alp-sebum is used in products that control oil on the face. and reduce the shine on the face
*Alpaflor Alp-sebum is used in production for acne-prone people.
*Alpaflor Alp-sebum is used to produce in the Oil free group.
*Alpaflor Alp-sebum is used products to control oiliness on the T –zone.
*Alpaflor Alp-sebum is used products for children and adolescents.
use products for men
*Alpaflor Alp-sebum is used Whitening treatments
*Alpaflor Alp-sebum is used in products for sensitive skin, combination skin, oily skin and to reduce pore size.



FUNCTIONS OF ALPAFLOR ALP-SEBUM:
•Alpaflor Alp-sebum is an innovative treatment
against oily skin and its related problems
•Alpaflor Alp-sebum reduces sebum production
and oily appearance of skin
•Alpaflor Alp-sebum reduces the size of pores
•Skin conditioning :
Alpaflor Alp-sebum maintains skin in good condition
•Antioxidant
•Sebum regulator
•Anti-inflammatory



ACTION OF ALPAFLOR ALP-SEBUM:
*Anti-inflammatory
*Pore refinement
*Purifying
*Shine control
*Mattifying
*purifying
*Seboregulator



PHYSICAL and CHEMICAL PROPERTIES of ALPAFLOR ALP-SEBUM:
Appearance: clear to slightly opalescent, amber to brown coloured, slightly viscous liquid with characteristic odour
Identity by HPLC: comparable chromatogram to that of internal reference standard
pH: 3.6 – 5.1
Relative density d20/20: 1.100 – 1.250
Refractive Index n25: 1.414 – 1.434
Oenotheins by HPLC: 120 – 500 mg / 100 g
(calculated as gallic acid)
Total aerobic mesophile plate count: < 100 CFU/g
Specified microorganisms: not detectable in one gram



FIRST AID MEASURES of ALPAFLOR ALP-SEBUM:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Rresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ALPAFLOR ALP-SEBUM:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of ALPAFLOR ALP-SEBUM:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ALPAFLOR ALP-SEBUM:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses.
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ALPAFLOR ALP-SEBUM:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of ALPAFLOR ALP-SEBUM:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Incompatible materials:
No data available



ALPHA ARBUTIN
Alpha Arbutin is in white crystalline powder form.
Alpha Arbutin is generally soluble in water or water-based solvents.


CAS Number: 84380-01-8
EC number: 440-470-8
MDL number: MFCD09838262
Molecular Formula: C12H16O7



4-Hydroxyphenyl α-D-glucopyranoside, Hydroquinone O-α-D-glucopyranoside, alpha-Arbutin, 84380-01-8, 4-Hydroxyphenyl a-D-glucopyranoside, alpha arbutin, 4-hydroxyphenyl alpha-D-glucopyranoside, a-Arbutin, UNII-72VUP07IT5, (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol, 72VUP07IT5,
ORISTAR AAT, alpha-D-Glucopyranoside, 4-hydroxyphenyl, CHEBI:29710, DTXSID20233358, (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydro-2H-pyran-3,4,5-triol, PubChem16460, AC1L4KBI, Alpha Arbutine, Alfa Arbutina, alpha-Arbutoside, MFCD09838262, I+/--Arbutin, 4-Hydroxyphenyl-alpha-D-glucopyranoside, .ALPHA.-ARBUTIN, ?-ARBUTIN, ALPHA-ARBUTIN [INCI], SCHEMBL435261, CHEMBL226495, ALPHA-ARBUTIN [WHO-DD], 4-hydroxyphenyl-D-lucopyranoside, DTXCID20155849, alpha-Arbutin, analytical standard, AMY22497, HY-N3002, a-D-Glucopyranoside, 4-hydroxyphenyl, s5112, AKOS015905235, CCG-267174, DB14109, N-CYCLOPROPYL-N-HYDROXYGUANIDINE, (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydropyran-3,4,5-triol, 1ST40211, AC-34884, AS-15466, CS-0022901, P-HYDROXYPHENYL-alpha-D-GLUCOPYRANOSIDE, EN300-7406351, P-HYDROXYPHENYL-.ALPHA.-D-GLUCOPYRANOSIDE, 4-HYDROXYPHENYL-.ALPHA.-D-GLUCOPYRANOSIDE, A840768, W-203913, Q27110235, (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydropyran-3,4,5-triol, alpha-Arbutin, Alpha-Arbutin, 4-Hydroxyphenyl-alpha-D-glucopyranoside, CAS No. 84380-01-8, EC No. 617-561-8,



Alpha Arbutin is a compound frequently used in the formulations of cosmetic products.
Alpha Arbutin helps reduce the appearance of dark spots, sun spots, age spots and other hyperpigmentation problems on the skin.
Alpha Arbutin helps regulate skin tone by controlling melanin production and regulating the activity of melanocytes.


Alpha Arbutin helps brighten and correct the overall tone of the skin.
Alpha Arbutin reduces dullness on the skin and makes the skin look more vibrant and even-toned.
Alpha Arbutin is in white crystalline powder form.


Alpha Arbutin is generally soluble in water or water-based solvents.
Alpha Arbutin is a glycoside.
Alpha Arbutin is a natural product found in Rhodiola chrysanthemifolia, Rhodiola sacra, and other organisms with data available.


Alpha Arbutin (4-hydroxyphenyl, αD-glucopyranoside) is a functional active ingredient for skin lightening.
Alpha Arbutin is biosynthetic component obtained from bearberry.
Alpha Arbutin is stable in the pH range of 5-7.


Alpha Arbutin is a water-based serum specifically designed to target uneven skin tone and visibly improve pigmentation.
Alpha Arbutin combines a high concentration of purified alpha arbutin, a well-known skin-brightening ingredient, with hyaluronic acid.
Purified alpha-arbutin works to target dark spots and uneven skin tone.


Meanwhile, hyaluronic acid helps to support product absorption into the skin.
Alpha Arbutin is extremely sensitive to degradation in the presence of water if the pH of the formulation is not ideal.
The pH of this formula has been shown to be the most suitable pH to minimize degradation of Alpha Arbutin.


Alpha arbutin has recently become one of the popular ingredients in the skin care world.
This effective and natural compound, Alpha Arbutin, is used to reduce the appearance of skin blemishes, even out skin tone and create a brightening effect.
Alpha Arbutin is a powerful ingredient that all skin types, including sensitive and acne-prone skin, can add to their care routine.


By using products containing Alpha Arbutin, you can help your skin look brighter, even-toned and younger.
Alpha Arbutin, a natural arbutin compound , is a substance known for its skin whitening properties.
Alpha Arbutin is a new type of active compound used to beautify and whiten skin.


Alpha Arbutin can be quickly absorbed into the skin and selectively inhibit tyrosinase activity.
Alpha Arbutin is a pure, water-soluble, biosynthetic active ingredient used in whitening skin care products.
Alpha Arbutin supports illumination and equal skin tone on all skin types.


Alpha Arbutin helps shrink age spots.
Alpha Arbutin reduces the degree of tanning of the skin after UV exposure.
Alpha arbutin is a choice brightening ingredient because it's a derivative of hydroquinone, one of the most effective skin-lightening and spot-fading actives out there.


Alpha Arbutin works by slowly releasing hydroquinone over time, inhibiting tyrosinase, the key enzyme responsible for the production of melanin, or pigment, in the skin.
In other words, less tyrosinase means less pigment, which means less discoloration and fewer unwanted dark spots.


And, along with its excellent brightening abilities, alpha arbutin is also known to have antioxidant and anti-inflammatory properties, she adds.
Alpha Arbutin, one of the most popular skin care ingredients of recent times, is frequently preferred for a brighter, even-toned and shiny skin.
Alpha Arbutin is an ingredient obtained from plants discovered by the Japanese and frequently used in skin care.


Alpha Arbutin, which has become popular thanks to the importance the Japanese attach to bright, even-toned and white skin, provides a 40% effect, according to research.
Alpha Arbutin is best known as an anti -dark spot ingredient.


Alpha Arbutin is a herbal ingredient derived from glucose molecules often found in blueberry fruit.
Apart from this, Alpha Arbutin is also found in wheat and cranberries.
By helping to prevent excess melanin production in the skin, Alpha Arbutin prevents dark spots that appear on the skin after problems such as sun exposure, aging and acne.


Alpha Arbutin takes its place in skin care with serums and arbutin creams .
If you are complaining about the appearance of dark spots on your skin or uneven skin tone, Alpha Arbutin content is just for you.
Alpha Arbutin helps whiten skin


Alpha Arbutin helps remove skin blemishes.
Alpha Arbutin evens skin tone
Alpha Arbutin makes the skin look brighter and brighter


Alpha Arbutin gives vitality to the skin
Alpha Arbutin minimizes sun damage
The stains on which Alpha Arbutin is effective are as follows: sunspots, Acne scars and blemishes, pregnancy spots, and age spots.


Alpha Arbutin is one of the most efficient skin brighteners, widely accepted and has been rated well by the consumers.
In vivo tests proved Alpha Arbutin is more effective at 1.0% than Beta-Arbutin and 9 times more effective than Beta-Arbutin in vitro.
Using specific enzyme transformation technology high purity is guaranteed.
Alpha Arbutin is a pure, water-soluble, crystalline, white to off-white powder for cosmetic application.



USES and APPLICATIONS of ALPHA ARBUTIN:
Alpha Arbutin is generally used in cosmetic products such as cream, serum, lotion or tonic.
The percentage of use may vary from product to product; while it is used at a rate of 1% to 2% in serums containing Alpha Arbutin, it can also be used at 0.1% or even lower rates in products such as creams and lotions.


Recommended concentration of Alpha Arbutin is 0.2-2%, add to the water phase of the formula, for best results use the product containing alpha-arbutin for at least 2-3 months.
Add Alpha Arbutin to formula at

The ideal pH range of Alpha Arbutin is 5-7.
Alpha Arbutin is used for external use only.
Alpha Arbutin is used all kinds of skin brightening products, including lotions, creams, make-up products.


It is a skincare product we developed to help care for skin tone inequalities that may develop due to pregnancy, sun and other environmental factors, with the support of alpha arbutin in its content.
While Alpha Arbutin contributes to the preservation of the skin's natural moisture balance with its Hyaluronic Acid content, it aims to help skin care for the appearance of redness with its moxibustion extract.


With regular use, a more even and smooth skin appearance is aimed with care for the appearance of dark spots that develop after sun exposure, aging and acne.
Alpha Arbutin, a type of glycoside found in plants and fruits, is processed into alpha arbutin and used in skin care products.


Alpha Arbutin helps reduce the appearance of dark spots on the skin and brighten the skin.
Alpha Arbutin helps the skin get a lighter and even tone by inhibiting melanin production.
Alpha Arbutin also has antioxidant properties and protects against free radicals.


Alpha Arbutin is a preferred ingredient in skin care products as a safe and effective whitening agent.
Alpha arbutin is a frequently heard and used ingredient in skin care.
Skin Whitening: Alpha arbutin helps reduce the appearance of dark spots on the skin and can pave the way for the skin to take on a lighter tone.


-Spot Removal : Alpha Arbutin is effective in reducing skin blemishes such as sun spots, aging spots or acne scars.
With regular use, Alpha Arbutin can lighten the appearance of blemishes on the skin.


-Skin Lightening:
Alpha arbutin brightens the skin, providing a healthier and brighter appearance.
Alpha Arbutin balances skin tone and prevents dull appearance.


-Antioxidant Effect:
Alpha arbutin has antioxidant properties.
Alpha Arbutin prevents skin damage caused by free radicals and protects the skin.


-Reducing Skin Inflammation:
Alpha arbutin can reduce skin inflammation and soothe irritated skin.
Each skin type may react differently to cosmetic products, so Alpha Arbutin is important to use the products correctly and consult a specialist dermatologist when necessary.

When choosing products containing alpha arbutin, Alpha Arbutin is important to turn to quality and reliable brands.
By using effective ingredients such as Alpha Arbutin correctly in skin care, you can achieve healthier and brighter skin.



BENEFITS OF ALPHA ARBUTIN:
*Alpha Arbutin helps equalize skin tone.
*Alpha Arbutin helps remove black spots on the skin.
*Alpha Arbutin helps smooth the skin.
*Alpha Arbutin provides care against sunspots.
*Alpha Arbutin provides a more natural look.
*Alpha Arbutin helps the skin look more vibrant when used on the face for a long time.
*Alpha Arbutin whitens the skin and gives a clear appearance.
*Alpha Arbutin is a herbal product.



USAGE OF ALPHA ARBUTIN:
Step 1 : First, clean your skin with tonic.
Step 2 : Then apply the serum to your skin with small massage movements.
Step 3 : Wait a few minutes for the serum to be absorbed.
Step 4 : After the application, moisturize your body with moisturizer.

Alpha Arbutin should be used as a serum twice a day.
After applying Alpha Arbutin to the skin in the morning, if it is a sunny day, sunscreen should be applied in the middle of the day.

As a moisturizer, Alpha Arbutin can be used whenever you want, with a minimum interval of 3-4 hours.
Alpha Arbutin is not as intense as a moisturizing serum and also helps nourish the skin.
You can use Alpha Arbutin again when your skin is dry.



HOW TO USE ALPHA ARBUTIN:
Alpha arbutin is often found in skin care products in serum, cream or lotion form.
Correct use ensures that Alpha Arbutin provides more effective results.
Here are some tips for using alpha arbutin:

Apply Alpha Arbutin to cleansed and dried skin.
Removing dirt and oil from the skin helps Alpha Arbutin absorb better.
Use alpha arbutin in amounts recommended by the manufacturer. Usually a few drops of product are sufficient.

Using too much product may irritate your skin unnecessarily.
Regular and continuous use is required to see the effects of alpha arbutin.
Apply the product regularly, in accordance with the frequency of use recommended on its packaging.

You can use the product containing alpha arbutin in harmony with other skin care products.
However, be careful when combining products containing more than one active and make sure your skin does not overreact.
You should use sunscreen products to reduce your risk of sun exposure while using alpha arbutin.

Alpha arbutin may increase skin sensitivity to the sun.
Remember, each skin type may react differently to the products used.

That's why Alpha Arbutin's important to test products or consult a dermatologist before using them.
In addition, precautions such as paying attention to the instructions for use and the manufacturer's recommendations allow you to get the best results from the use of alpha arbutin.



BENEFITS OF ALPHA ARBUTIN:
*Alpha Arbutin supports skin brightening and even skin tone on all skin types
*Alpha Arbutin reduces the extent of skin tanning after UV exposure
*Alpha Arbutin helps minimize the appearance of liver spots



HOW TO USE ALPHA ARBUTIN?
In your day and night skin care routine, after cleansing your skin, take a few drops on your fingertips and apply by massaging.
We recommend using sunscreen after daily use.
Anti-pigmentation daily care serum containing high purity Alpha Arbutin and Hyaluronic Acid to even out skin tone, brighten and reduce dark spots.



WHAT IS ALPHA ARBUTIN FOR?
Anti-pigmentation daily care serum containing high purity Alpha Arbutin and Hyaluronic Acid to even out skin tone, brighten and reduce dark spots.



HOW TO USE ALPHA ARBUTIN?
After cleansing your skin, apply Alpha Arbutin a few drops to your face during the day and night routine.
There is no need to rinse after application.
Regular use is recommended to get better results.



FEATURES OF ALPHA ARBUTIN:
*INCI name (active): Alpha-Arbutin
*Scientifically proven effects at low concentrations
*More effective at 1.0% than Beta-Arbutin in vivo
-Nine times more effective than Beta-Arbutin in vitro
-Outstanding tyrosinase inhibition activity in vitro
*Highly pure biosynthetic active ingredient
*High performing enzyme related biotechnology
*Does not contain intentionally added substances regulated/listed as preservative
*Halal compliant (porcine and alcohol free, not certified)



BENEFITS OF ALPHA ARBUTIN:
*Ensures an even skin tone after only one month
*Reduces the degree of skin tanning after UV exposure
*Helps to minimize the appearance of liver spots



MODE OF ACTION OF ALPHA ARBUTIN:
Alpha Arbutin exhibits impressive tyrosinase inhibition and is nine times more effective than Beta-Arbutin.
Very low IC50 values indicates the power of Alpha Arbutin.
The outstanding efficacy of Alpha Arbutin is due to its perfect affinity to the active site of tyrosinase.



WHY WE LOVE ALPHA ARBUTIN:
Alpha Arbutin contains concentrated 2% alpha arbutin, a natural skin brightener, together with 1% Kojic Acid, in a water soluble serum that aims to help improve the appearance of age spots and an uneven skin tone.



MORE DETAILS OF ALPHA ARBUTIN:
Alpha Arbutin helps to balance confused complexions and even out the skin’s texture helping to target age spots and skin prone to pigmentation.
Kojic Acid, often used in creams, is a natural alternative to hydroquinone-based products, which may cause inflammation.
This Kojic Acid serum displays powerful antioxidant properties helping to protect the pigment-producing cells.

Alpha Arbutin 2% serum is Cruelty-free, suitable for Vegetarians and free from Alcohol and Silicones. Serum bottles are made of PET and are 100% recyclable.
pH range of Alpha Arbutin is 7.6 -7.7.

Directions:
Apply a sufficient amount of Alpha Arbutin to cleansed skin, both morning and evening.
Alpha Arbutin may be used with other serums.



APPLICATION METHOD OF ALPHA ARBUTIN:
Wash your face with a gentle cleanser and dry it.
A few drops of White Miè in the morning and evening; Apply the serum to your entire face, neck and décolleté area.

To increase Alpha Arbutin's benefits, Shine Miè; Apply with Vitamin C Serum.
White Miè; Alpha Arbutin is water based, apply before the moisturizing step.
Protect your morning routine with SPF 50 +; be sure to finish with broad spectrum sunscreen.

It is important to remember that fading pigmentation takes time and to use Alpha Arbutin regularly according to the instructions for at least 8 weeks to see results.
If you apply this serum to your skin regularly, you will see that Alpha Arbutin is extremely effective.



HOW TO USE ALPHA ARBUTIN:
Apply Alpha Arbutin with massage movements in the morning and/or evening onto cleansed and dry skin, avoiding the eye area.
Use Alpha Arbutin before moisturizers or oil treatments.

Alpha Arbutin is an optical isomer of naturally occurring arbutin (or beta-arbutin).
Just like its sibling, Alpha Arbutin is also a skin-brightening, depigmenting agent.



BENEFITS OF ALPHA ARBUTIN:
*Reduces the appearance of dark spots
*Reduces uneven skin tone
*PH 4.85 - 4.90
*Cruelty-free & Vegan



KEY INGREDIENTS OF ALPHA ARBUTIN:
*Alpha Arbutin
*Hyaluronic Acid
*Formulated Without
*Fragrance
*Alcohol
*Gluten
*Nuts
*Silicone
*Parabens
*Sulfates
*Mineral Oil
*Methylchloroisothiazolinone
*Methylisothiazolinone
*Animal Oils
*Coal Tar Dyes
*Formaldehyde
*Mercury
*Oxybenzone



HOW TO USE ALPHA ARBUTIN?
You can apply Alpha Arbutin serums or arbutin creams by massaging them onto your clean skin.
When you use Alpha Arbutin in the morning, you should not forget to use sunscreen during the day.



WHEN IS ALPHA ARBUTIN USED?
We can answer the question of when to use Alpha Arbutin as follows:
You can use Alpha Arbutin serum twice a day, in the morning and in the evening.



CAN ALPHA ARBUTIN BE USED IN SUMMER?
Can Alpha Arbutin be used in summer? is one of the questions we encounter most frequently.
Like all ingredients, especially stain ingredients, Alpha Arbutin can be used in summer, but it must be supported with a sunscreen containing SPF 50.
Otherwise, new spots may occur due to the sun.



HOW LONG DOES IT TAKE TO SEE THE EFFECT OF ALPHA ARBUTIN?
As with all ingredients, it may be necessary to use Alpha Arbutin regularly for at least 1 month to see its effect.
Depending on the depth of the spots on the skin, results can be seen in 6 months.



CAN ALPHA ARBUTIN BE USED WITH NIACINAMIDE?
Can Alpha Arbutin be used with niacinamide?
Both Alpha Arbutin and niacinamide ingredients are effective on skin blemishes.
Therefore, instead of using separate products, you can choose serums formulated together in the right proportions.
Using high amounts of Alpha Arbutin and niacinamide ingredients separately may cause skin sensitivity.



CAN VITAMIN C BE USED WITH ALPHA ARBUTIN?
Alpha Arbutin and vitamin C can be used together to make the skin look bright and shiny.
For this, you can use vitamin C in the morning and Alpha Arbutin in the evening.
Or you can create a routine where you have vitamin C one day and vitamin C the next day.
In both cases, you should definitely use SPF 50 sunscreen.



WHAT ARE THE HARMS OF ALPHA ARBUTIN?
Since Alpha Arbutin is a herbal ingredient, it does not cause much harm to the skin.
However, like any ingredient, Alpha Arbutin may cause a reaction on very sensitive and allergic skin.
In order to minimize the possibility of skin reactions caused by skin care ingredients, Alpha Arbutin is recommended to first try them on a small part of the skin and then gradually acclimate the skin to use them.



PHYSICAL and CHEMICAL PROPERTIES of ALPHA ARBUTIN:
Molecular Weight: 272.25 g/mol
XLogP3: -0.7
Hydrogen Bond Donor Count: 5
Hydrogen Bond Acceptor Count: 7
Rotatable Bond Count: 3
Exact Mass: 272.08960285 g/mol
Monoisotopic Mass: 272.08960285 g/mol
Topological Polar Surface Area: 120Ų
Heavy Atom Count: 19
Formal Charge: 0
Complexity: 279
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 5
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes



FIRST AID MEASURES of ALPHA ARBUTIN:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ALPHA ARBUTIN:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ALPHA ARBUTIN:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ALPHA ARBUTIN:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ALPHA ARBUTIN:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Store at Room Temperature.
Light sensitive



STABILITY and REACTIVITY of ALPHA ARBUTIN:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available


ALPHA BISABOLOL

Alpha-bisabolol, also known as bisabolol or levomenol, is a natural monocyclic sesquiterpene alcohol that is derived from various plant sources.
Alpha bisabolol is a colorless to pale yellow liquid with a pleasant floral aroma.
Alpha-bisabolol is recognized for its soothing and skin-conditioning properties, and it is commonly used in cosmetic and skincare products.

CAS Number: 515-69-5
EC Number: 208-205-9



APPLICATIONS


Alpha bisabolol finds extensive use in skincare formulations due to its soothing and calming properties.
Alpha bisabolol is a common ingredient in moisturizers, helping to maintain skin hydration and suppleness.
Alpha bisabolol's anti-inflammatory nature makes it valuable in products targeting redness and irritation.

Alpha bisabolol is often included in after-sun products to alleviate discomfort caused by sun exposure.
The compound's antimicrobial properties contribute to its inclusion in skincare for blemish-prone skin.
Alpha bisabolol is utilized in serums and creams designed to reduce the appearance of fine lines and wrinkles.

Alpha bisabolol is a sought-after component in products formulated to improve the overall complexion and skin tone.
Alpha bisabolol's gentleness makes it suitable for use in baby skincare products to maintain skin comfort.

Alpha bisabolol is used in body lotions to provide a soothing and luxurious feel during daily skincare routines.
Alpha bisabolol's fragrance profile makes it a valuable addition to perfumes and scented body care.
Alpha bisabolol is incorporated into facial cleansers for its ability to cleanse and calm the skin simultaneously.

Alpha bisabolol's wound-healing potential makes it suitable for inclusion in skincare for post-procedure care.
Alpha bisabolol contributes to the soothing effects of facial masks, enhancing the overall experience.
Alpha bisabolol is used in men's grooming products to alleviate skin irritation caused by shaving.

Alpha bisabolol is found in under-eye creams to reduce puffiness and provide a refreshed appearance.
Alpha bisabolol's anti-irritant properties make it useful in deodorants for sensitive underarm skin.
Alpha bisabolol is utilized in body washes and shower gels to create a relaxing and skin-friendly cleansing experience.
Alpha bisabolol's anti-inflammatory effects contribute to its use in formulations targeting skin conditions like eczema.

Alpha bisabolol is included in lip balms to soothe and protect the delicate skin of the lips.
Alpha bisabolol's compatibility with sensitive skin makes it a staple in products for individuals with sensitivities.

Alpha bisabolol is used in foot creams to provide relief and comfort to tired and achy feet.
Alpha bisabolol's presence in hand creams and lotions helps maintain soft and nourished hands.
Alpha bisabolol is incorporated into facial mists to offer a quick and refreshing burst of hydration and calmness.

Alpha bisabolol's compatibility with various formulations makes it versatile for both leave-on and rinse-off products.
Alpha bisabolol is a valuable addition to natural and organic skincare lines, aligning with consumer preferences for plant-based ingredients.
Alpha bisabolol is commonly included in night creams and overnight masks to promote skin rejuvenation while the skin is at rest.

Its skin-soothing properties make it a preferred ingredient in post-hair removal products to calm irritated skin.
Alpha bisabolol's non-sensitizing nature allows it to be used in formulations for those with reactive or allergy-prone skin.

Alpha bisabolol can be found in facial toners to balance the skin's pH levels and prepare it for subsequent skincare steps.
Alpha bisabolol's calming effects extend to scalp care, where it is used in shampoos and conditioners to soothe sensitive scalps.

Alpha bisabolol is utilized in makeup primers to create a smooth canvas and minimize the appearance of redness.
Alpha bisabolol's natural origin aligns with clean beauty principles, making it a popular choice in natural and organic cosmetics.
Alpha bisabolol is included in body oils to provide a luxurious and soothing massage experience.
Alpha bisabolol's anti-inflammatory properties are harnessed in acne spot treatments to reduce redness and swelling.

Alpha bisabolol can be found in bath products to create a calming and aromatherapeutic bathing experience.
Alpha bisabolol contributes to the nourishing effects of hand masks and treatments, addressing dry and rough skin.
Alpha bisabolol is included in skincare for menopausal skin, helping to address the changes in skin texture and sensitivity.
Alpha bisabolol is used in makeup remover formulations to gently dissolve makeup without stripping the skin's moisture.

Alpha bisabolol can be incorporated into intimate care products to soothe and support delicate areas.
Alpha bisabolol's fragrance profile makes it an appealing addition to scented body lotions and body sprays.
Alpha bisabolol is utilized in pre-shave products to soften and prepare the skin for a smoother shaving experience.

Alpha bisabolol is found in multi-purpose balms for its ability to provide targeted relief to various skin concerns.
Alpha bisabolol is used in scalp treatments and serums to address scalp sensitivity and promote a healthier hair environment.

Alpha bisabolol contributes to the calming effects of baby skincare products, supporting the well-being of delicate skin.
Alpha bisabolol can be found in stretch mark creams to help improve the appearance of skin texture.
Alpha bisabolol's compatibility with various product formats allows for its inclusion in gel-based, cream-based, and oil-based formulations.
Alpha bisabolol is utilized in formulations for mature skin to address age-related concerns like dryness and fine lines.

Alpha bisabolol contributes to the comfort of post-exfoliation products by reducing potential irritation.
Alpha bisabolol is included in skincare routines targeting redness and rosacea, helping to create a more even complexion.
Alpha bisabolol's role in cosmetic formulations emphasizes its adaptability and value in promoting skin health and enhancing the overall sensory experience of skincare and personal care products.

Alpha bisabolol's versatility extends to hair care, where it can be found in hair masks and treatments to nourish and calm the scalp.
Alpha bisabolol is used in sun care products to soothe and reduce redness caused by UV exposure.

Alpha bisabolol's gentle properties make it suitable for use in products for sensitive areas like the bikini line and underarms.
Alpha bisabolol can be incorporated into makeup setting sprays to provide a refreshing and skin-soothing finishing touch.
Alpha bisabolol contributes to the comfort of post-workout body products by alleviating skin discomfort.

Alpha bisabolol is found in body scrubs and exfoliants to enhance the overall skin texture and leave the skin feeling soft and refreshed.
Alpha bisabolol's compatibility with various skincare actives allows it to be combined with other ingredients for enhanced benefits.
Alpha bisabolol can be included in natural deodorants to provide odor protection while minimizing skin irritation.
Alpha bisabolol is used in primers to create a smooth canvas for makeup application.

Alpha bisabolol contributes to the soothing effects of sheet masks, providing a spa-like experience at home.
Alpha bisabolol can be found in lip treatments to alleviate dryness and provide a comfortable feel.
Alpha bisabolol is incorporated into hand sanitizers to counteract the potential drying effects of alcohol.

Alpha bisabolol's versatility makes it a suitable addition to facial oils, serums, and emulsions.
Alpha bisabolol is used in formulations targeting skin conditions like psoriasis and eczema due to its anti-inflammatory effects.
Alpha bisabolol contributes to the sensory experience of aromatherapy products, enhancing relaxation and well-being.
Alpha bisabolol can be found in anti-aging products to support skin's resilience and youthful appearance.

Alpha bisabolol's compatibility with water-based and oil-based formulations expands its application possibilities.
Alpha bisabolol is utilized in foot scrubs and creams to create a revitalizing and soothing foot care routine.

Alpha bisabolol's inclusion in body mists offers a light and refreshing way to enjoy its calming benefits.
Alpha bisabolol can be incorporated into products for sensitive scalp care to address itchiness and discomfort.
Alpha bisabolol is used in formulations targeting skin redness and irritation caused by environmental stressors.
Alpha bisabolol contributes to the skin-loving effects of overnight sleeping masks, promoting a radiant morning complexion.

Alpha bisabolol's mild aroma makes it a favored choice for subtly scented skincare products.
Alpha bisabolol can be found in products for post-exercise recovery to provide a cooling and calming sensation.

Alpha bisabolol's widespread use underscores its importance in modern skincare, where it enhances product efficacy and user experience while catering to a variety of skin needs and preferences.
Alpha bisabolol is harnessed in facial serums to deliver concentrated soothing benefits to targeted areas.
Alpha bisabolol contributes to the calming effects of facial mists, providing an instant sense of comfort and hydration.

Alpha bisabolol's compatibility with natural and synthetic ingredients makes it a versatile choice for formulation.
Alpha bisabolol is used in anti-redness products to help balance skin tone and reduce the appearance of redness.

Alpha bisabolol can be found in body creams and lotions for an all-over soothing and moisturizing experience.
Alpha bisabolol is utilized in night balms and sleeping masks to promote overnight skin renewal and restoration.
Alpha bisabolol's lightweight texture allows it to be included in fast-absorbing products like body sprays.

Alpha bisabolol contributes to the calming effects of aftershave products, soothing freshly shaved skin.
Alpha bisabolol is incorporated into barrier creams to support the skin's protective barrier function.
Alpha bisabolol can be found in products for tattoo aftercare, helping to soothe and protect new tattoos.

Alpha bisabolol is used in intimate care formulations to provide comfort and support for delicate areas.
Alpha bisabolol contributes to the luxurious feel of massage oils, enhancing the overall relaxation experience.
Alpha bisabolol's potential for reducing the appearance of scars makes it a valuable addition to scar-fading products.

Alpha bisabolol can be found in body powders to provide a silky and soothing touch to the skin.
Alpha bisabolol's anti-irritant effects make it a beneficial ingredient in products for post-inflammatory skin concerns.
Alpha bisabolol is utilized in makeup remover wipes to gently cleanse and soothe the skin without stripping moisture.

Alpha bisabolol contributes to the skin-soothing effects of cleansing oils, maintaining skin comfort during cleansing.
Alpha bisabolol can be incorporated into BB creams and tinted moisturizers for its multitasking skin benefits.
Alpha bisabolol is used in hand sanitizing gels to counteract potential skin dryness.
Alpha bisabolol contributes to the skin-loving effects of body butters, offering deep hydration and comfort.

Alpha bisabolol is found in eye creams to provide a delicate and soothing care for the eye area.
Alpha bisabolol is used in spot treatments for its ability to calm and alleviate redness in specific areas.
Alpha bisabolol's adaptability extends to various product formats, from creams to gels and oils.
Alpha bisabolol contributes to the formulation of products for facial redness, helping to create a more even complexion.
Alpha bisabolol's presence in a wide array of skincare and personal care products exemplifies its versatility and effectiveness in enhancing overall skin well-being while catering to diverse preferences and needs.



DESCRIPTION


Alpha-bisabolol, also known as bisabolol or levomenol, is a natural monocyclic sesquiterpene alcohol that is derived from various plant sources.
Alpha bisabolol is a colorless to pale yellow liquid with a pleasant floral aroma.
Alpha-bisabolol is recognized for its soothing and skin-conditioning properties, and it is commonly used in cosmetic and skincare products.

Its chemical structure is characterized by a bicyclic ring system and an alcohol functional group.
Alpha bisabolol can be found in essential oils from plants such as chamomile (Matricaria recutita or Chamomilla recutita), which is one of the primary sources of this compound.

Alpha-bisabolol has various applications in the cosmetics and personal care industry due to its potential benefits for the skin.
Alpha bisabolol is known for its anti-inflammatory, anti-irritant, and antimicrobial properties, making it a popular ingredient in skincare formulations.
Alpha bisabolol can help calm and soothe sensitive or irritated skin, making it suitable for products designed for individuals with sensitive skin or skin conditions.

Alpha bisabolol is a natural monocyclic sesquiterpene alcohol derived from various plant sources.
Alpha bisabolol is characterized by its colorless to pale yellow appearance and a pleasant, delicate floral aroma.
Alpha bisabolol is widely recognized for its soothing and skin-conditioning properties.
Alpha bisabolol is found in essential oils of plants like chamomile, contributing to its therapeutic qualities.

Its chemical structure features a bicyclic ring system and an alcohol functional group.
Alpha bisabolol is revered for its anti-inflammatory properties, making it suitable for calming irritated skin.

With its antimicrobial characteristics, it assists in protecting the skin from certain harmful microorganisms.
Alpha bisabolol is a popular ingredient in cosmetics and skincare products due to its skin-friendly nature.
Alpha bisabolol is often utilized in formulations targeting sensitive or easily irritated skin types.
Alpha bisabolol is known to alleviate redness, itching, and discomfort caused by various skin conditions.
Alpha bisabolol's gentle nature makes it an ideal choice for products designed for all skin types, including sensitive ones.

Alpha bisabolol has been studied for its potential to support wound healing and reduce the appearance of scars.
The aroma of Alpha bisabolol, reminiscent of floral notes, lends itself to its inclusion in fragrances and perfumes.
Its versatility allows it to be incorporated into various cosmetic formulations, including lotions and creams.
Alpha bisabolol's presence in skincare products contributes to the overall soothing and comforting effects.

Alpha bisabolol is extracted from natural sources, aligning with the trend toward plant-based and sustainable ingredients.
Alpha bisabolol is considered a safe ingredient for topical applications and is generally well-tolerated by most individuals.
Alpha bisabolol's anti-irritant properties are particularly beneficial in products designed for post-sun exposure care.
Its ability to alleviate discomfort from environmental stressors makes it a valuable component in skincare routines.
Alpha bisabolol's inclusion in cosmetics reflects the industry's focus on providing effective and gentle skincare solutions.

As a natural ingredient, Alpha bisabolol adds a touch of authenticity to formulations seeking to align with consumers' preferences.
Its presence in skincare products contributes to a sense of relaxation and well-being during self-care routines.
Alpha bisabolol's multifaceted benefits make it a sought-after ingredient in both professional and everyday skincare.
Alpha bisabolol is often found in moisturizers, serums, sunscreens, and other products that prioritize skin health and comfort.
Alpha bisabolol's rich history of use in traditional remedies converges with modern science to create a versatile and valuable component in contemporary cosmetic formulations.



FIRST AID


Inhalation:

If Alpha bisabolol is inhaled and respiratory irritation occurs, move the affected person to fresh air immediately.
If breathing difficulties persist, seek medical attention.


Skin Contact:

In case of skin contact, gently remove any contaminated clothing and rinse the affected area with plenty of water.
Wash skin thoroughly with mild soap and water.
If irritation or redness develops, discontinue use and seek medical advice.
If skin irritation persists or worsens, seek medical attention.


Eye Contact:

If Alpha bisabolol comes into contact with the eyes, immediately flush the eyes with plenty of water for at least 15 minutes, while holding the eyelids open.
Remove contact lenses, if present and easy to do, and continue rinsing.
If eye irritation persists, seek medical attention.


Ingestion:

If Alpha bisabolol is ingested accidentally and symptoms such as nausea, vomiting, or gastrointestinal discomfort occur, do not induce vomiting.
Rinse the mouth thoroughly with water and seek medical attention.
Do not give anything to drink to an unconscious person.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment:
When handling Alpha bisabolol, especially in concentrated forms, consider wearing appropriate personal protective equipment (PPE) such as gloves and safety goggles to prevent direct skin or eye contact.

Avoid Inhalation:
Minimize inhalation exposure by working in well-ventilated areas or using appropriate respiratory protection if necessary.

Avoid Contact:
Avoid direct skin contact with undiluted Alpha bisabolol.
If contact occurs, wash the affected area thoroughly with water and mild soap.

Hygiene Practices:
After handling, wash hands thoroughly with soap and water before touching your face or other sensitive areas.


Storage:

Cool and Dry:
Store Alpha bisabolol in a cool, dry, and well-ventilated area away from direct sunlight and heat sources.

Temperature:
Keep the storage temperature within the recommended range, usually indicated on the product label or technical data sheet.

Containers:
Ensure that containers used for storing Alpha bisabolol are tightly sealed to prevent moisture ingress and contamination.

Incompatibilities:
Avoid storing Alpha bisabolol near incompatible substances, such as strong oxidizers or strong acids, to prevent reactions.

Separation:
If the compound has a tendency to separate or settle over time, gently agitate or mix the container before use to ensure uniformity.



SYNONYMS


Bisabolol
Levomenol
(−)-alpha-Bisabolol
α-Bisabolol
6-Isopropenyl-3,8-dimethyl-1,10-dioxaspiro[4.5]decane-2,9-diol
3-(6-Isopropenyl-4-methyl-2-cyclohexen-1-yl)-2,3-dihydro-2,3-dihydroxy-7-benzofuranol
6-Isopropenyl-3,8-dimethyl-1,10-dioxaspiro[4.5]decane-2,9-diol
Levorotatory alpha-Bisabolol
EINECS 208-205-9
(-)-alpha-Bisabolol
2,9-Dihydro-3-(6-isopropenyl-4-methyl-2-cyclohexen-1-yl)-2,3-dihydroxy-6,7-benzofurandione
(-)-Levomenol
(3R)-alpha-Bisabolol
1,3-Cyclohexadiene, 1-methyl-4-(1-methylethenyl)-5-(2-methyl-2-propenyl)-2-(1-methylethyl)-, trans-endo-2-norbornylmethyl ether, (1R,3aR,5aS)-rel-
Panosol
3-(6-Isopropenyl-2-methylcyclohexen-1-yl)-2,3-dihydroxy-6,7-benzofurandione
(1R)-endo-2-Norbornylmethyl 1-methyl-4-(1-methylethenyl)-5-(2-methyl-2-propenyl)-2-(1-methylethyl)-1-cyclohexenedicarboxylate
(1R,3aR,5aS)-rel-1-Methyl-4-(1-methylethenyl)-5-(2-methyl-2-propenyl)-2-(1-methylethyl)-1,3-cyclohexadiene
1R-Endo-2-Norbornylmethyl 1-methyl-4-(1-methylethenyl)-5-(2-methyl-2-propenyl)-2-(1-methylethyl)-1-cyclohexenedicarboxylate
(1R,3aR,5aS)-rel-1-Methyl-4-(1-methylethenyl)-5-(2-methyl-2-propenyl)-2-(1-methylethyl)cyclohexene-1,3-dicarboxylate
Bisabolol, (-)-
trans-Endo-2-norbornylmethyl 1-methyl-4-(1-methylethenyl)-5-(2-methyl-2-propenyl)-2-(1-methylethyl)-1-cyclohexenedicarboxylate
Endo-2-Norbornylmethyl 1-methyl-4-(1-methylethenyl)-5-(2-methyl-2-propenyl)-2-(1-methylethyl)-1-cyclohexenedicarboxylate
(-)-Levobisabolol
(R)-(-)-alpha-Bisabolol
L-alpha-Bisabolol
Levorotatory Bisabolol
S-(-)-alpha-Bisabolol
Endo-2-Norbornylmethyl (1R)-1,4-dimethyl-7-(1-methylethenyl)-2,3-dioxabicyclo[2.2.2]octane-3-propanoate
S-(+)-alpha-Bisabolol
(R)-Levobisabolol
Panosol II
(R)-Bisabolol
S-(+)-Bisabolol
S-(-)-Bisabolol
(-)-Bisabolol
S-(−)-alpha-Bisabolol
(-)-alpha-Bisabolol (natural)
(1R,3aR,5aS)-rel-1,3,3a-Trimethyl-5-[(2R)-6-methyl-2,7-octadien-1-yl]cyclohexyl (R)-2,3-epoxypropanoate
(R)-(+)-Bisabolol
(−)-alpha-Bisabolol (natural)
2,3-Epoxypropyl (R)-endo-2-norbornylmethyl (1R)-1,4-dimethyl-7-(1-methylethenyl)-2,3-dioxabicyclo[2.2.2]octane-3-propanoate
2,3-Epoxypropyl Levobisabolol
(1R)-1,4-Dimethyl-7-(1-methylethenyl)-2,3-dioxabicyclo[2.2.2]octane-3-propanoic Acid 2,3-Epoxypropyl Ester
L-Bisabolol
L-(-)-alpha-Bisabolol
(1R)-endo-2-Norbornylmethyl (1R)-1,4-Dimethyl-7-(1-methylethenyl)-2,3-dioxabicyclo[2.2.2]octane-3-propanoate
(-)-Panosol II
Levorotatory alpha-Bisabolol
(1R)-endo-2-Norbornylmethyl (1R)-1,4-Dimethyl-7-(1-methylethenyl)-2,3-dioxabicyclo[2.2.2]octane-3-propanoic Acid 2,3-Epoxypropyl Ester
Levobisabolene
(1R)-(-)-Bisabolol
(R)-Bisabolol
(-)-Bisabolene
(R)-(-)-alpha-Bisabolol
1R-endo-2-Norbornylmethyl (R)-1,4-Dimethyl-7-(1-methylethenyl)-2,3-dioxabicyclo[2.2.2]octane-3-propanoate
L-endo-Bisabolol
(R)-(-)-Levobisabolol
(−)-Levobisabolol
(R)-Bisabolene
(-)-Bisabolol (natural)
(R)-(-)-Bisabolene
(R)-alpha-Bisabolol (natural)
1R-(-)-alpha-Bisabolol
(R)-Levobisabolol (natural)
(1R)-(-)-alpha-Bisabolol
(-)-Bisabolol (natural)
(R)-(-)-alpha-Bisabolene
Levobisabolol (natural)
(R)-(-)-alpha-Bisabolol (natural)
1R-endo-2-Norbornylmethyl (R)-1,4-Dimethyl-7-(1-methylethenyl)-2,3-dioxabicyclo[2.2.2]octane-3-propanoic Acid 2,3-Epoxypropyl Ester
(R)-(+)-Levobisabolol
(R)-(-)-alpha-Bisabolol (endo-2-norbornylmethyl 1,4-dimethyl-7-(1-methylethenyl)-2,3-dioxabicyclo[2.2.2]octane-3-propanoate)
L-alpha-Bisabolene
3-endo-Norbornylmethyl 1-methyl-4-(1-methylethenyl)-5-(2-methyl-2-propenyl)-2-(1-methylethyl)cyclohex-3-ene-1-carboxylate
ALPHA BISABOLOL
DESCRIPTION:

Alpha Bisabolol is a natural product.
Alpha Bisabolol accelerates the healing process of the skin.
Alpha Bisabolol is a natural active ingredient that protects the skin from the effects of environmental stress.



CAS NUMBER: 515-69-5

EC NUMBER: 208-205-9

MOLECULAR FORMULA: C15H26O

MOLECULAR WEIGHT: 222.37 g/mol



DESCRIPTION:

Alpha Bisabolol has an anti-inflammatory effect.
Alpha Bisabolol promotes faster healing of wounds, heals skin irritations and soothes the skin.
The active ingredient is also suitable for sensitive skin.
Alpha Bisabolol is a sesquiterpene with a warm floral scent similar to honey, apple and chamomile.

Alpha Bisabolol is widely used in many products such as products designed for sensitive skin, baby care products, shaving and aftershave products, after-sun products.
Alpha Bisabolol is added to cosmetics as an active ingredient.
Among other things, Alpha Bisabolol is used as an anti-inflammatory and to reduce irritation.
These properties have been reasonably researched and substantiated, making it a suitable substance for use in aftershave.

Alpha Bisabolol is a colourless to slightly yellow liquid at room temperature.
Alpha Bisabolol is a clear oily liquid that contains at least 95% alpha-Bisabolol.
Alpha Bisabolol was extracted from the chamomile flowers, which contain an average of 30% of the active ingredient.
Alpha Bisabolol is a natural, colorless, viscous oil that is derived from the chamomile plant.

Alpha Bisabolol is also known by other names such as levomenol or bisabolol.
Alpha Bisabolol is a sesquiterpenoid.
Alpha Bisabolol is widely used in the cosmetic and skincare industry due to its soothing, anti-inflammatory, and skin-healing properties.
Alpha Bisabolol has a mild, floral scent and is often used as a fragrance component in various cosmetic products.

Alpha Bisabolol is known for its skin-conditioning benefits and is used in creams, lotions, moisturizers, and other skincare formulations.
Alpha Bisabolol has been studied for its potential antioxidant and antimicrobial properties.
Alpha Bisabolol is believed to help protect the skin from environmental damage and can assist in reducing redness and irritation.
Alpha Bisabolol is often used in formulations targeting sensitive, dry, or irritated skin, as it can help soothe and calm the skin.
Alpha Bisabolol is considered to be well-tolerated and gentle, making it suitable for use in products for sensitive or delicate skin.

Alpha Bisabolol is often included in formulations for products aimed at reducing the appearance of wrinkles, fine lines, and age spots.
Alpha Bisabolol's important to note that while alpha-bisabolol is generally considered safe for topical use, individuals with specific allergies or sensitivities
Alpha Bisabolol is suitable for all types of cosmetic formulations due to its stability and good compatibility with the skin.
Alpha Bisabolol is extracted through fractional distillation of the candeia essential oil coming from the wood of the candeia tree, endemic from Brazil.
Alpha Bisabolol is well known for its soothing, anti-inflammatory and anti-microbial properties.

Alpha Bisabolol is thought to provide antioxidant effects for the skin that may help the appearance of aging.
Alpha Bisabolol is applied topically to calm irritated skin.
Alpha Bisabolol prevents the breakdown of collagen, thereby saving the skin from losing essential structural protein.
Alpha Bisabolol helps the skin to shine and tighten.

Alpha Bisabolol contains vitamin B5, which are natural humectants, so it acts as a moisture reservoir.
Alpha Bisabolol does not allow the skin to lose moisture.
Alpha Bisabolol also has a natural scent that gives a soothing feeling.
Alpha Bisabolol mixes easily into the body secretion and also facilitates the penetration of other ingredients into the skin layers.
Alpha Bisabolol also contains antimicrobial power that helps acne-prone skin heal faster.

Alpha Bisabolol is nontoxic and nonirritating to the skin and has been shown to have anti-inflammatory and wound healing properties.
Alpha Bisabolol also shows anti-microbial activity, particularly against certain fungi.
Alpha Bisabolol is suitable for use in skin care products where the formulator wishes to take advantage of its anti-inflammatory and anti-microbial properties.
As such Alpha Bisabolol may be useful for protection of skin against stresses including cleansing, shaving, depilation, and sun exposure.
Alpha Bisabolol is also a useful ingredient in natural deodorants.

Alpha Bisabolol is a natural monocyclic sesquiterpene alcohol.
Alpha Bisabolol is a colorless viscous oil that is the primary constituent of the essential oil.
High concentrations of Alpha Bisabolol can also be found in certain medicinal cannabis cultivars.
Alpha Bisabolol is poorly soluble in water and glycerine, but soluble in ethanol.
Alpha Bisabolol is also found naturally but is rare.

Synthetic bisabolol is usually a racemic mixture of the two, α-(±)-bisabolol.
Alpha Bisabolol is the terpenoid responsible for distinctive aroma of chamomile flowers, and when isolated, its scent has also has been likened to apples, sugar and honey.
Alpha Bisabolol has a weak sweet floral aroma and is used in various fragrances.
Alpha Bisabolol has also been used for hundreds of years in cosmetics because of its skin healing properties including reducing wrinkles, skin toughness and repairing sun-damaged skin, and more recently it has been compounded with tretinoin as a topical treatment for acne.

Alpha Bisabolol is known to have anti-irritant, anti-inflammatory, and anti-microbial properties.
Alpha Bisabolol is also demonstrated to enhance the percutaneous absorption of certain molecules and has found use as a penetration enhancer: an agent used in topical formulations, increasing the substances propensity for absorption beneath the skin.
A structurally related compound known as Alpha Bisabolol differs only in the position of the tertiary alcohol functional group.
Alpha Bisabolol is natural monocyclic sesquiterpene alcohol.

Alpha Bisabolol is non-toxic sesquiterpene alcohol, present in natural essential oils, with anticancer activity.
Alpha Bisabolol occurs naturally.
Alpha Bisabolol is widely used in personal care products and cosmetics because of its floral fragrance and many beneficial properties for the skin.
Alpha Bisabolol is also simply called Bisabolol or Levomenol.
Alpha Bisabolol contains panthenol, which is a humectant that causes the skin to retain moisture.

Alpha Bisabolol dries out less quickly and the skin remains well hydrated.
In addition, the substance penetrates into the deeper layers of the skin, which also prevents skin aging.
Alpha Bisabolol also causes other ingredients in a product to penetrate deeper into the skin.
This happens with oils, but also with vitamins, antioxidants, or minerals.

Alpha Bisabolol is, therefore, an improvement for a care product.
Alpha Bisabolol is a monocyclic unsaturated sesquiterpene alcohol, alpha-bisabolol.
Alpha Bisabolol contains at least 95 % of alpha-bisabolol.
The content of Alpha Bisabolol is less than 0.1 % / 1000 ppm.

Alpha Bisabolol is quite close to a known ingredient of chamomile.
Alpha Bisabolol is known for its soothing effect and widely used in skin care cosmetics.
Alpha Bisabolol is an ideal ingredient for stressed and sensitive skin cosmetics
Alpha Bisabolol is the major active component of Chamomile.
Alpha Bisabolol has long been used in cosmetics for its anti-inflammatory, healing & soothing, and anti-microbial properties.

The most important effects of Alpha Bisabolol for the use in cosmetics are anti-inflammatory, wound-healing, anti-bacterial and anti-mycotic.
Alpha Bisabolol is therefore perfectly suited for the use in all kinds of skin-care products.
Alpha Bisabolol can be used as active substance in cosmetic preparations for the protection and care of sensitive skin, preparations for babies and children, sunscreen and after-sun products, aftershaves and preparations for the oral hygiene.
Alpha Bisabolol is an antimicrobial and anti-inflammatory agent.

Alpha Bisabolol provides wound healing properties.
Alpha Bisabolol is used in skin care formulations.
Alpha Bisabolol is a cosmetic active ingredient and aromachemical that occurs naturally in chamomile, among other things.
Alpha Bisabolol is widely used for its skin healing properties, due to its anti-inflammatory & anti-bacterial benefits, commonly used in shaving & sun burn products for those very reasons.



USAGE AREAS:

-sensitive skin
-baby care products
-shaving and after shave products
-after-sun products.



USES:

To benefit from the beneficial effects of Alpha Bisabolol in personal care products, it is smart to add it in a certain way.
You should never use the product undiluted on the skin.
Alpha Bisabolol is suitable for dry, red, and sensitive skin, but also usable for anti-aging care.

-fragrance
-skin conditioning
-soothing agents



COSMETIC APPLICATIONS:

-Products for sensitive skin
-Baby care products
-After-shave preparations
-After-sun formulations
-Cosmeceuticals



BENEFITS:

-Skin conditioning
-Anti-inflammatory
-Clear, colorless, oil-soluble liquid
-Very low odor
-Dermatologically and toxicologically safe
-IL-1a - TNFa and LTB4 inhibition
-Hyaluronic Acid stimulator



FEATURES:

-Anti-inflammatory properties
-A natural, fresh, woody aroma fresh aroma that naturally soothes the skin.
-Contains 95% alpha-bisabol
-Known to aid muscle ache, burns and dehydrated skin.



PROPERTIES:

-Hair care
-Purifying/Detox
-Soothing
-Sun care



PROPERTIES:

-Molecular Weight: 222.37 g/mol
-XLogP3-AA: 3.8
-Hydrogen Bond Donor Count: 1
-Hydrogen Bond Acceptor Count: 1
-Rotatable Bond Count: 4
-Exact Mass: 222.198365449 g/mol
-Monoisotopic Mass: 222.198365449 g/mol
-Topological Polar Surface Area: 20.2Ų
-Heavy Atom Count: 16
-Complexity: 284
-Isotope Atom Count: 0
-Defined Atom Stereocenter Count: 0
-Undefined Atom Stereocenter Count: 2
-Defined Bond Stereocenter Count: 0
-Undefined Bond Stereocenter Count: 0
-Covalently-Bonded Unit Count: 1
-Compound Is Canonicalized: Yes



PROPERTIES:

-Quality Level: 100
-Assay: ≥93% (GC)
-optical activity: [α]/D -58±5°, neat
-refractive index: n20/D 1.496
-SMILES string: C\C(C)=C\CC[C@](C)(O)[C@H]1CCC(C)=CC1



PHYSICAL AND CHEMICAL ACTIONS:

Alpha Bisabolol is active against primary acute leukemia cells, including BCR-ABL(+) acute lymphoblastic leukemias.
Alpha Bisabolol is the inhibitor of voltage-dependent Ca(2+) channels in tracheal smooth muscle preparations of rat.
Alpha Bisabolol also inhibits human and rat glioma cell growth and survival.
Alpha Bisabolol is a potential new therapeutic agent against leishmaniasis.



PHYSICAL PROPERTIES:

-Appearance: colorless clear viscous liquid
-Assay: 95.00 to 100.00
-Boiling Point: 314.00 to 315.00 °C. at 760.00 mm Hg
-Vapor Pressure: 0.000040 mmHg at 25.00 °C.
-Flash Point: 275.00 °F. TCC ( 135.00 °C. )
-logP (o/w): 5.070




SPECIFICATIONS:

-Density: 0.93
-Flash Point: 135°C (275°F)
-Refractive Index: 1.495
-Sensitivity: Air Sensitive
-Solubility Information: Soluble in alcohol,natural,mineral and synthetic oils. Insoluble in water.
-Formula Weight: 222.37
-Percent Purity: 96%
-Physical Form: Liquid



STORAGE:

Store away from oxidizing agents.
Keep the container tightly closed and place it in a cool, dry and well ventilated condition.



SYNONYM:

6-methyl-2-(4-methylcyclohex-3-en-1-yl)hept-5-en-2-ol
Bisabolol
515-69-5
(+/-)-alpha-Bisabolol
6-Methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol
Anymol
72059-10-0
EINECS 276-310-7
(+)-anymol
6-methyl-2-(4-methylcyclohex-3-enyl)hept-5-en-2-ol
(R*,S*)-(1)-alpha,4-Dimethyl-alpha-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol
Dragosantol
Camilol
3-Cyclohexene-1-methanol, .alpha.,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)-, (.alpha.R,1R)-rel-
a-Bisabolol
Hydagen B
EINECS 208-205-9
EINECS 246-973-7
dl-.alpha.-Bisabolol
epi-.alpha.-Bisabolol
6-epi-.alpha.-Bisabolol
7-epi-.alpha.-Bisabolol
NSC606842
(R*,R*)-alpha,4-Dimethyl-alpha-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol
MLS001304113
SCHEMBL172398
.alpha.,4-Dimethyl-.alpha.-(4-methyl-3-pentenyl)-3-cyclohexene-1-methanol
3-Cyclohexene-1-methanol, ?,4-dimethyl-?-(4-methyl-3-pentenyl)-, (R,R)-
3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-
DTXSID80859437
(alpha R,1R)-rel-alpha,4-Dimethyl-alpha-(4-methyl-3-penten-1-yl)-3-cyclohexene-1-methanol
(R*, R*)- a, 4- dimethyl- a- (4- methyl- 3- pentenyl)cyclohex- 3- ene- 1- methanol
(R*,R*)-(1)-alpha,4-Dimethyl-alpha-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol
(R*,R*)-.alpha.,4-Dimethyl-.alpha.-(4-methyl-3-pentenyl)-3-cyclohexene-1-methanol
(R*,R*)-.alpha.,4-Dimethyl-.alpha.-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol
3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (alphaR,1R)-rel-
3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (R*,R*)-
CHEBI:167422
(R*,R*) - a,4 - dimethyl - a - (4 - methyl - 3 - pentenyl)cyclohex - 3 - ene - 1 - methanol
3-ciclohexeno-1-metanol, Alfa,4-Dimetil-Alfa-(4-metil-3-penten-1-il)-, (Alfa R, 1R)-rel-
3-Cyclohexene-1-methanol, .alpha.,4-dimethyl-.alpha.-(4-methyl-3-penten-1-yl)-, (.alpha.R,1R)-rel-
3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (theta,theta)-(+/-)-
BBL018680
STK111280
AKOS005398189
bisabolol, same as "alpha-Bisabolol".
NSC-606842
LS-74679
SMR000037359
VS-06724
A7604
B2119
FT-0615565
FT-0777837
W-110632
6-Methyl-2-(4-Methyl-1-Cyclohex-3-enyl)Hept-5-en-2-ol
(?)-6-Methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol
alpha,4-Dimethyl-alpha-(4-methyl-3-pentenyl)-3-cyclohexene-1-meth- anol
(R*,R*)-(+/-)-,4-Dimethyl-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol
(R*,S*)-(+-)-alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol
3-Cyclohexene-1-methanol,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)-, (R*,R*)-
26560-22-5
72691-24-8
















ALPHA BISABOLOL
Alpha Bisabolol is non-toxic sesquiterpene alcohol, present in natural essential oils, with anticancer activity.
Alpha Bisabolol is widely used in personal care products and cosmetics because of its floral fragrance and many beneficial properties for the skin.
Alpha-bisabolol, also known as bisabolol or levomenol, is a natural monocyclic sesquiterpene alcohol that is found in various plants.

CAS Number: 515-69-5
Molecular Formula: C15H26O
Molecular Weight: 222.37
EINECS Number: 208-205-9

Alpha Bisabolol occurs naturally in the Brazilian Candeia tree.
Alpha Bisabolol is a monocyclic, unsaturated sesquiterpene alcohol used as an anti-irritant in Skincare products.
Alpha Bisabolol is most commonly obtained from the essential oil of chamomile (Matricaria recutita) and the South American tree Candeia.

Alpha Bisabolol is a clear, viscous liquid with a faint floral scent.
Alpha Bisabolol targets key inflammatory mediators (IL-1α, IL6, IL8 & TNF-α) and stimulates hyaluronan synthesis, enhancing hydration and reducing SDS erythema induced back to a normal level as fast as two days.
Alpha Bisabolol is soothing and has anti-redness properties.

Alpha Bisabolol is a naturally occurring plant extract that was first isolated from the German chamomile, Matricaria chamomilla.
It has since been identified in various aromatic plants around the world, and is a major component of the African alpine sage Salvia runcinata essential oil.
Alpha Bisabolol and bisabolol-rich oils are found in skincare products and pharmaceuticals as both an active and inactive constituent due its well-established beneficial properties such as anti-inflammatory and antibacterial.

While the German chamomile and African alpine sage may contain up to 50 and 90% Alpha Bisabolol, respectively, the Brazilian Eremanthus erythropappus is also another bisabolol-rich source containing up to 85% of it.
Alpha Bisabolol is colourless in nature and has a mild floral scent making it a common ingredient in decorative cosmetics.
Alpha-bisabolol possesses anti-inflammatory properties, making it effective in soothing and calming irritated skin.

Alpha Bisabolol can help reduce redness, swelling, and itching, making it useful for sensitive or reactive skin types.
Alpha Bisabolol promotes the skin's natural healing process and can aid in the repair of damaged skin.
Alpha Bisabolol has been shown to enhance the skin's barrier function, improve moisture retention, and support the regeneration of skin cells.

Alpha Bisabolol exhibits antimicrobial activity against certain bacteria and fungi.
Alpha Bisabolol can help inhibit the growth of bacteria on the skin and is sometimes used in products formulated for acne-prone or blemished skin.
Alpha Bisabolol has moisturizing properties and can help improve the overall texture and appearance of the skin.

Alpha Bisabolol can enhance skin smoothness and elasticity, giving a soft and supple feel.
Alpha Bisabolol has antioxidant properties that help protect the skin from oxidative stress and free radical damage.
This can contribute to reducing the signs of aging, such as fine lines, wrinkles, and uneven skin tone.

Alfa Bisabolol (Bisabolife) is a colourless to slightly yellow liquid at room temperature.
Alpha Bisabolol has a fairly long shelf life: store in a cool, dry, dark place and in well-closed packaging.
Alpha Bisabolol, also known as Alpha Bisabolol or levomenol, is the primary constituent of German Chamomile (Matricaria chamomilla or Matricaria recutita), and is also found naturally in the bark of the Candeia (Vanillosmopsis erythropappa) tree of Brazil, which accounts for most of the world's production of this ingredient.

Alpha Bisabolol is a terpene and is classed as an alcohol. Our product is produced from the bark of the Candeia tree which is harvested in a sustainable manner.
Alpha Bisabolol is a naturally occurring active ingredient that accelerates the healing process of skin and protects it from the effects of daily stress.
Known to have anti-irritant and anti-inflammatory properties, Alpha Bisabolol has been shown to reduce UV-induced erythema in-vivo.

Alpha Bisabolol has also been demonstrated in studies to enhance the dermal penetration of other ingredients, making it a truly versatile active ingredient for skin care products, especially those containing other active ingredients and cosmeceuticals.
Alpha Bisabolol also has natural anti-bacterial as well as anti-mycotic properties.

Alpha Bisabolol, or more formally α-(−)-bisabolol or also known as levomenol, is a natural monocyclic sesquiterpene alcohol.
Alpha Bisabolol is a colorless viscous oil that is the primary constituent of the essential oil from German chamomile (Matricaria recutita) and Myoporum crassifolium.
High concentrations of bisabolol can also be found in certain medicinal cannabis cultivars.

Alpha Bisabolol is poorly soluble in water and glycerine, but soluble in ethanol.
The enantiomer, α-(+)-bisabolol, is also found naturally but is rare.
Synthetic Alpha Bisabolol is usually a racemic mixture of the two, α-(±)-bisabolol.

Alpha Bisabolol is the terpenoid responsible for distinctive aroma of chamomile flowers, and when isolated, its scent has also has been likened to apples, sugar and honey.
Alpha Bisabolol is a well-known skin soothing agent.
It comes in two different structural forms: alpha-bisabolol, derived from chamomile and other plants (although it can also be lab-created) vs. beta-bisabolol which is found in cotton and corn.

Alpha bisabolol, often shortened to bisabolol, is also known as levomenol, a naturally occurring compound that is the primary constituent of the essential oil from German chamomile.
Bisabolol may also be manufactured synthetically, where it is chemically identical to that found in nature.
It’s one of those ingredients that is a heavy hitter when it comes to skin care yet sits quietly in the background doing its thing, without drawing much attention to itself.

Alpha Bisabolol has been shown to have anti-irritant, anti-inflammatory and anti-microbial features.
Alpha Bisabolol also can help to increase the absorption of certain ingredients.
It is high in panthenol, a B vitamin, which assists with helping to heal and moisturize skin and hair.

Alpha Bisabolol has been used in skin care preparations due to its healing properties And, it’s weak, sweet floral aroma makes it a useful addition to fragrances.
Alpha Bisabolol is commonly found in many personal care products, including moisturisers, cleansers, and serums.
Alpha Bisabolol often plays a bio-active skin-calming role thanks to its anti-inflammatory properties and shows up in many products designed for sensitive skin.

Beyond Alpha Bisabolols soothing properties, research indicates bisabolol may offer some discoloration-fading capabilities.
The naturally sweet, slightly floral scent of Alpha Bisabolol means it is sometimes used in higher amounts to impart fragrance to a formula.
Alpha Bisabolol, in lower amounts it doesn’t impart much, if any, scent and its soothing compounds easily outweigh any risk of irritation.

Alpha Bisabolol is typically derived from chamomile, and chamomile is a member of the ragweed family, it may be best to avoid it if you have a confirmed allergy to ragweed.
As a raw material, Alpha Bisabolol is a colourless to light yellow, oily liquid.
Alpha Bisabolol, or more specifically (-)-α-bisabolol, is an unsaturated, optically active sesquiterpene alcohol obtained by distillation of essential oils from natural source plants.

The dermatological and pharmaceutical versatility of Alpha Bisabolol is apparent when examining the variety of its biochemical targets with each target responsible for carrying out a different function.
Some of the most well-characterized functions of Alpha Bisabolol are clinically studied in humans and rodents to examine the biochemical basis of each.
The most notable functions are anti-inflammatory, antibacterial, anti-nociceptive, anti-tumor, and its use in hyperpigmentation treatment.

Natural alpha-Bisabolol, also known as Levomenol, may be obtained from the direct distillation of the oil from the tropical shrub candeia.
This shrub, Linnean name Vanillosmopsis erythropappa, which is of the Asteraceae family, grows in the southeast and midwest regions of Brazil.
This tree yields a white, hard, resinous wood and its leaves, flowers and oil have medicinal properties.

Alfa Bisabolol (Bisabolife) is a cosmetic active ingredient and aromachemical that occurs naturally in chamomile, among other things.
Natural alpha-Bisabolol is also a major constituent of German Chamomile [Chamomilla Recutita (Matricaria) Flower Oil], which has been used in the traditional medicines of Europe for hundreds of years.
The essential oil of chamomile contains up to 50% 1-alpha-bisabolol.

Alpha-Bisabolol Natural is an optically active viscous colorless to somewhat yellow liquid with slight characteristic floral wood odor.
Alpha Bisabolol contains at least 95% (-)-1-alpha-bisabolol, a monocyclic unsaturated sesquiterpene alcohol.
Alpha-Bisabolol, which is nontoxic and nonirritating to the skin, has been shown to possess anti-inflammatory and wound healing properties, as well as antimycotic and antibacterial effects.

Alpha-Bisabolol Natural is suitable for use in skin care products where the formulator wishes to take advantage of its anti-inflammatory, bactericidal and antimycotic properties, which make it a preferred active ingredient for protection of skin against stresses including cleansing, shaving, depilation, and sun exposure.
When Alpha-Bisabolol Natural is used at low levels (0.1 – 1.0% is recommended), it is active, safe, and skin compatible.

The clear colourless oil is easy to use and has a very low odour.
Alpha Bisabolol is soluble in common cosmetic oils, ethanol and glycols.
Alpha Bisabolol is stable over a wide range of pH and up to 80c.

Alpha bisabolol is the ideal plant active ingredient to soothe and repair sensitive skin.
Alpha bisabolol, also called bisabolol, is an excellent natural, mild and calming active agent, highly used in skincare for its anti-inflammatory, healing, antipruritic, antibacterial, soothing and restorative actions.
This natural super ingredient is the ally of sensitive, irritated and delicate skin, helping to relieve them and improve their appearance.

Alpha Bisabolol also prevents the breakdown of collagen helping to protect against sagging skin, fine lines and wrinkles, and acts on melanin synthesis to reduce dark spots for brighter, firmer and smoother skin.
The alpha bisabolol contained in the organic beauty and natural skin care products selected by Ecocentric is exclusively of natural origin, extracted from chamomile.

Melting point: 25°C
Boiling point: 154-156°C
Density: 0.93 g/mL at 20 °C(lit.)
refractive index: n20/D 1.496
Flash point: 135°C
storage temp.: Refrigerator
solubility: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
pka: 15.04±0.29(Predicted)
form: Liquid
color: Clear Colourless
Odor: at 100.00 %. mild floral peppery balsamic clean
Odor Type: floral
Water Solubility: Soluble in alcohol, natural, mineral and synthetic oils. Insoluble in water.
Merck: 14,1241
BRN: 5733954
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
LogP: 5.63

It's one of the active parts of Chamomile that contains about 30% of Alpha Bisabolol.
Alpha Bisabolol's a clear oily fluid that is used in skincare as a nice anti-inflammatory and soothing ingredient.
Derived from a tropical shrub the oil contains 95% alpha-bisabol which has been widely used in traditional medicine for centuries.

A floral woody aroma, this oil is widely used for its skin healing properties, due to its anti-inflammatory & anti-bacterial benefits, commonly used in shaving & sun burn products for those very reasons.
As previously noted, the essential oils of both chamomile and candeia are good botanical sources for preparing 95+% pure (-) alpha-Bisabolol.
Alpha Bisabolol can also be made by chemical synthesis.

Alpha Bisabolol thus obtained, however, is only about 85% pure Bisabolol and, further, is a racemic mixture of both levorotary and dextrorotary isomers.
So the synthetic product contains only about 42% of active (-) isomer.
When considering the cost effectiveness of natural vs. synthetic material, remember that 1 kg natural Alpha-Bisabolol contains a minimum of 950 g active (-) Alpha-Bisabolol, while 1 kg synthetic Alpha-Bisabolol contains only about 425 g active (-) Alpha-Bisabolol.

So on an “actives” basis, RTD Alpha-Bisabolol Natural is about 2.24 times more potent than synthetic material.
Alpha-bisabolol has a pleasant, mild floral scent, which makes it a popular ingredient in fragrances and perfumes.
Alpha Bisabolols gentle aroma is often used to add a soothing and calming note to various cosmetic and personal care products.

Alpha Bisabololl has emollient properties, meaning it helps to soften and smooth the skin.
Alpha Bisabolol forms a protective film on the skin's surface, reducing water loss and improving overall hydration.

Studies have suggested that alpha-bisabolol can help inhibit the production of melanin, the pigment responsible for skin color.
This property has led to its use in some skin whitening and brightening products.

Alpha Bisabolol has been found to promote wound healing by stimulating the growth of new cells and collagen synthesis.
Alpha Bisabolol can be used in topical formulations for minor cuts, burns, and skin abrasions.

Alpha-bisabolol is also utilized in hair care products.
Alpha Bisabolol can help condition the hair, improve manageability, and provide a soothing effect to the scalp.
Alpha Bisabolol is known for its anti-aging properties.

Alpha Bisabolol helps to improve the appearance of fine lines, wrinkles, and age spots.
Alpha Bisabolol promotes skin elasticity and firmness, giving a more youthful complexion.
Alpha Bisabolol has been found to possess antimicrobial properties, which make it effective against certain types of bacteria and fungi.

This property can be beneficial in skincare products aimed at addressing acne or other microbial-related skin conditions.
Alpha Bisabolol exhibits strong anti-inflammatory properties, which can help calm and soothe irritated or inflamed skin.
It can be beneficial for sensitive or reactive skin types, including those with conditions like rosacea or eczema.

Alpha Bisabolol acts as an antioxidant, helping to neutralize free radicals that contribute to skin damage and premature aging.
Alpha Bisabolol helps protect the skin from environmental stressors such as pollution and UV radiation.
Due to its ability to inhibit the production of melanin, alpha-bisabolol is also used in skincare products targeting hyperpigmentation or uneven skin tone.

Alpha Bisabolol is often included in lip balms and lip care products due to its moisturizing and soothing properties.
Alpha Bisabolol helps to hydrate the lips and prevent dryness and chapping.
Alpha Bisabolol can be used in eye creams or serums to address puffiness, dark circles, and fine lines around the delicate eye area.

Alpha Bisabolol helps to soothe and rejuvenate the skin, reducing the appearance of tiredness or fatigue.
Alpha Bisabolol is a naturally occurring compound derived from various plant sources.
Alpha Bisabolol is commonly extracted from chamomile oil, but it can also be found in other botanical extracts such as candeia tree or yarrow.

Due to its anti-inflammatory properties, alpha-bisabolol is beneficial in reducing skin irritation caused by various factors, including environmental aggressors, shaving, or hair removal.
Alpha Bisabolol's soothing and anti-inflammatory properties make it suitable for alleviating the discomfort associated with sunburns.
It can help calm the skin and reduce redness and inflammation.

Alpha Bisabolol Natural is well-absorbed following dermal exposure, and formulators should be aware of the potential for Bisabolol to increase the penetration of other components of cosmetic formulations.
Alpha Bisabolol is a naturally occurring compound that is derived from the Candeia Tree.
It has a pleasant woody and floral aroma, which makes it a useful addition to fragrances.

This wonderful ingredient is extremely beneficial when used in skincare products.
Alpha Bisabolol has been shown to possess anti-inflammatory, anti-bacterial and skin healing properties.
Alpha Bisabolol can help soothe and moisturise the skin, whilst reducing dryness and restoring suppleness.

Alpha Bisabolol is a natural antioxidant. It can help protect your skin from pollution and free radicals and assist with repairing any damaged caused by these.
The natural face oil nourishes all skin types and lends the complexion a velvety and soft feel.
The oil balances, evens out the complexion and brightens the skin by enhancing brightness, especially on skin types that are lacklustre and prone to hyperpigmentation.

Uses
Alpha Bisabolol is a botanical used for its anti-inflammatory and soothing properties. It is derived from chamomile and/or yarrow.
Alpha Bisabolol finds its application as a masking agent, skin conditioning agent and soothing agent in cosmetics industry.
The most important effects of Bisabolol for the use in cosmetics are anti-inflammatory, wound-healing, anti-bacterial and anti-mycotic.

Alpha Bisabolol is therefore perfectly suited for the use in all kinds of skin-care products It can be used as active substance in cosmetic preparations for the protection and care of sensitive skin, preparations for babies and children, sunscreen and after-sun products, aftershaves and preparations for the oral hygiene.
Alpha Bisabolol, add the extract can to creams, lotions, foaming products (skin and hair), winter skin care, anti-ageing products, after-sun products, rinse off and oral care as part of the production process of your cosmetics or by adding to the Naturallythinking range of Cosmetic bases.

Alpha Bisabolol is a popular ingredient in skincare formulations such as creams, lotions, serums, and masks.
Alpha Bisabolol is used for its soothing, anti-inflammatory, and moisturizing properties.

Due to its ability to promote skin elasticity and reduce the appearance of wrinkles, alpha-bisabolol is often included in anti-aging products like moisturizers, serums, and eye creams.
Alpha Bisabolol is sometimes added to sunscreen formulations for its anti-inflammatory properties.
Alpha Bisabolol helps to calm and soothe the skin, providing relief from sunburn or irritation.

Alpha Bisabolols antimicrobial and anti-inflammatory properties make alpha-bisabolol beneficial in products targeting acne and blemish-prone skin.
It can help reduce redness, inflammation, and the appearance of acne lesions.

Alpha Bisabolol's moisturizing and soothing properties make it a common ingredient in lip balms, lip creams, and lip treatments.
Alpha Bisabolol helps to hydrate and nourish the lips, preventing dryness and chapping.
Alpha Bisabolol is also used in hair care products such as shampoos, conditioners, and hair masks.

Alpha Bisabolol can help soothe and moisturize the scalp, reducing itchiness and dryness.
Alpha Bisabolol is used as a fragrance ingredient in perfumes, colognes, and other scented products.
Alpha Bisabolol adds a subtle, floral note to the fragrance composition.

Some toothpaste and mouthwash formulations include alpha-bisabolol for its antimicrobial properties.
It can help combat oral bacteria, reduce inflammation, and freshen breath.

Alpha Bisabolol's anti-inflammatory and soothing properties make it suitable for use in wound healing products, such as ointments or creams.
Alpha Bisabolol can help reduce redness, promote tissue regeneration, and accelerate the healing process.
Alpha-bisabolol is utilized in deodorant formulations for its ability to neutralize odor-causing bacteria and provide a pleasant scent.

Its soothing and anti-inflammatory properties make alpha-bisabolol effective in products designed to relieve itching and irritation caused by insect bites, rashes, or allergic reactions.
Alpha-bisabolol is sometimes added to nail care products such as cuticle creams and nail strengtheners.
Alpha Bisabolol helps to moisturize and condition the nails and cuticles, promoting healthy nail growth.

Alpha Bisabolol's calming and relaxing properties make it suitable for use in massage oils.
Alpha Bisabolol can help relieve muscle tension and promote a sense of relaxation.
Due to its soothing and cooling effects, alpha-bisabolol is commonly used in after-sun lotions, gels, and sprays.

Alpha Bisabolol helps to alleviate sunburn, redness, and skin inflammation.

Alpha Bisabolol is favored in natural and organic cosmetic formulations due to its plant-derived origin and skin-friendly properties.
Its gentle nature makes alpha-bisabolol suitable for products formulated for sensitive or delicate skin.
It can help calm and soothe reactive skin types.

Alpha Bisabolol can be found in various makeup products, including foundations, concealers, and primers.
It helps to provide a smooth application, reduce redness, and improve overall skin appearance.
Alpha Bisabolol is incorporated into bath salts, shower gels, and body washes for its skin-soothing and aromatic properties.

Its anti-inflammatory and soothing properties make alpha-bisabolol beneficial in aftershave balms or lotions.
Alpha Bisabolol helps to calm the skin and reduce post-shave irritation.
Some pre-shave oils or gels contain alpha-bisabolol to prepare the skin for a smoother and more comfortable shaving experience.

Alpha-bisabolol's gentle and calming properties make it suitable for use in baby care products, including diaper creams, baby lotions, and baby wipes.
Alpha-bisabolol is sometimes incorporated into men's grooming products like aftershaves and shaving creams.
It helps to soothe the skin and reduce post-shave irritation.

Historically, people have used alpha bisabolol medicinally for its anti-irritant, anti-inflammatory and anti-microbial properties.
In cosmetics, it performs as a skin conditioning agent where it enhances the appearance of dehydrated or damaged skin by reducing dryness and flakiness and restoring suppleness.
Because of its high panthenol concentration, it can effectively stimulate and promote the skin’s healing process and encourage healthy hair growth.

Alpha Bisabolols ability to enhance the penetration of other cosmetics ingredients makes it a useful addition to treatments that contain other actives including antioxidants, peptides and retinoids.
Alpha Bisabolols skin soothing and anti-inflammatory properties are beneficial not only when it comes to wound healing, but also in calming irritated skin.

Alpha Bisabolol has a weak sweet floral aroma and is used in various fragrances.
Alpha Bisabolol has also been used for hundreds of years in cosmetics because of its skin healing properties including reducing wrinkles, skin toughness and repairing sun-damaged skin, and more recently it has been compounded with tretinoin as a topical treatment for acne.

Alpha Bisabolol is known to have anti-irritant, anti-inflammatory, and anti-microbial properties.
Alpha Bisabolol is also demonstrated to enhance the percutaneous absorption of certain molecules and has found use as a penetration enhancer: an agent used in topical formulations, increasing the substances propensity for absorption beneath the skin.

Sensitivity or Allergic Reactions
While alpha-bisabolol is well-tolerated by most individuals, some people may be sensitive or allergic to it.
If have a known allergy to chamomile or related plants, it's advisable to avoid products containing alpha-bisabolol.

Eye Irritation
Direct contact with alpha-bisabolol or products containing it may cause mild eye irritation in some individuals.
Alpha Bisabolol is recommended to avoid direct contact with the eyes and to flush them with water if irritation occurs.

Contamination Risks
If alpha-bisabolol is not properly stored or handled, it may be subject to contamination with microorganisms or impurities.
Manufacturers should adhere to proper quality control measures to ensure the safety and purity of the ingredient.

Specific Precautions
While alpha-bisabolol itself does not pose significant hazards, it's important to consider the overall formulation of a product.
Some products containing alpha-bisabolol may also include other ingredients that have their own hazards or contraindications.
It's essential to follow the instructions and warnings provided by the manufacturer.

Synonyms
alpha-Bisabolol
6-methyl-2-(4-methylcyclohex-3-en-1-yl)hept-5-en-2-ol
Bisabolol
515-69-5
(+/-)-alpha-Bisabolol
6-Methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol
Anymol
72059-10-0
EINECS 276-310-7
(+)-anymol
6-methyl-2-(4-methylcyclohex-3-enyl)hept-5-en-2-ol
(R*,S*)-(1)-alpha,4-Dimethyl-alpha-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol
Dragosantol
Camilol
3-Cyclohexene-1-methanol, .alpha.,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)-, (.alpha.R,1R)-rel-
a-Bisabolol
Hydagen B
EINECS 208-205-9
EINECS 246-973-7
dl-.alpha.-Bisabolol
epi-.alpha.-Bisabolol
6-epi-.alpha.-Bisabolol
7-epi-.alpha.-Bisabolol
NSC606842
(R*,R*)-alpha,4-Dimethyl-alpha-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol
MLS001304113
SCHEMBL172398
.alpha.,4-Dimethyl-.alpha.-(4-methyl-3-pentenyl)-3-cyclohexene-1-methanol
3-Cyclohexene-1-methanol, ?,4-dimethyl-?-(4-methyl-3-pentenyl)-, (R,R)-
3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-
DTXSID80859437
(alpha R,1R)-rel-alpha,4-Dimethyl-alpha-(4-methyl-3-penten-1-yl)-3-cyclohexene-1-methanol
(R*, R*)- a, 4- dimethyl- a- (4- methyl- 3- pentenyl)cyclohex- 3- ene- 1- methanol
(R*,R*)-(1)-alpha,4-Dimethyl-alpha-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol
(R*,R*)-.alpha.,4-Dimethyl-.alpha.-(4-methyl-3-pentenyl)-3-cyclohexene-1-methanol
(R*,R*)-.alpha.,4-Dimethyl-.alpha.-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol
3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (alphaR,1R)-rel-
3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (R*,R*)-
CHEBI:167422
(R*,R*) - a,4 - dimethyl - a - (4 - methyl - 3 - pentenyl)cyclohex - 3 - ene - 1 - methanol
3-ciclohexeno-1-metanol, Alfa,4-Dimetil-Alfa-(4-metil-3-penten-1-il)-, (Alfa R, 1R)-rel-
3-Cyclohexene-1-methanol, .alpha.,4-dimethyl-.alpha.-(4-methyl-3-penten-1-yl)-, (.alpha.R,1R)-rel-
3-Cyclohexene-1-methanol, alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)-, (theta,theta)-(+/-)-
BBL018680
STK111280
AKOS005398189
bisabolol, same as "alpha-Bisabolol".
NSC-606842
LS-74679
SMR000037359
VS-06724
A7604
B2119
FT-0615565
FT-0777837
W-110632
6-Methyl-2-(4-Methyl-1-Cyclohex-3-enyl)Hept-5-en-2-ol
(?)-6-Methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol
alpha,4-Dimethyl-alpha-(4-methyl-3-pentenyl)-3-cyclohexene-1-meth- anol
(R*,R*)-(+/-)-,4-Dimethyl-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol
(R*,S*)-(+-)-alpha,4-dimethyl-alpha-(4-methyl-3-pentenyl)cyclohex-3-ene-1-methanol
3-Cyclohexene-1-methanol,4-dimethyl-.alpha.-(4-methyl-3-pentenyl)-, (R*,R*)-
26560-22-5
72691-24-8
ALPHA OLEFIN SULFONATE (AOS)
DESCRIPTION:
Alpha-Olefin sulfonates (also: alpha-olefin sulfonates or AOS) are a group of anionic surfactants, which are used as detergents.
The compounds contain a - mostly linear, primary - alkyl R and a monovalent cation M, preferably sodium.
The most frequently used example of this group of substances is sodium α-olefin sulfonate (INCI: Sodium C14-16 Olefin Sulfonate).

Cas Number :68439-57-6
EC # 931-534-0
Chemical Formula : CnH2n-1SO3Na (n= 14 - 16)
Molecular Weight : 324.00


Alpha Olefin Sulfonate (AOS) is is mostly derived from coconut oils.
Alpha Olefin Sulfonate (AOS) is typically created by processes such as ethylene oligomerization, or by the Fischer-Tropsch process of synthesis.
The sulphonation process starts inside a continuous thin film reactor.
High-temperature hydrolysis reacts with sultones to form a mixture of cyclic sulfonate esters and alkene sulfonic acids.

This is followed by incorporating aqueous sodium hydroxide to neutralize the mix.
Neutralization and hydrolysis are carried out in isopropanol instead of water in order to form Alpha olefin sulfonates in solid form.

Alpha olefin sulfonate features excellent cleaning and degreasing properties, strong wetting effect, foam booster, slight viscosity enhancer.
Alpha Olefin Sulfonate (AOS) is compatible with other surfactants, including amphoteric and non-ionic co-surfactants.

Alpha Olefin Sulfonate (AOS) is gentle on the skin, without drying effects, which makes it ideal for making sulfate-free cleansing products.
Those features, along with decent biodegradability, lead to the high popularity of Alpha olefin sulfonate as a cosmetic ingredient.
In general, non-sulfate anionic surfactants are gradually becoming the prime solution for use in personal care cleansing products, particularly for scalp and hair care.

The most common AOS used in cosmetics is sodium C14-16 olefin sulfonate.
This multifunctional variety can act as a detergent, emulsifier, and wetting agent.
Properly formulated, it enhances viscosity, foaming properties, and the production of a stable lather.

Alpha olefin sulfonate can be added to formulas on its own, in a range of 4-30% of the final product. The concentration depends on desired properties, such as foaming and cleansing effects.
In addition to a longer hydrocarbon chain in which there must be at least one double bond (hence the name "olefin"), it has an anionic sulfonate headgroup with a sodium ion as a counterion.
The sulfonate group is negative in aqueous solution, which is why the α-olefin sulfonates are among the anionic surfactants.


In contrast to most other surfactants in which the C12-alkyl chains have the highest surface activity, olefin sulfonates shows maximal activity when using C14and C16-olefins.
Alpha Olefin Sulfonate (AOS) is a kind of surfactants provide outstanding detergency, high compatibility with hard water, and good wetting and foaming properties.


Alpha Olefin Sulfonate (AOS) is free of skin irritants and sensitizers, and it biodegrades rapidly.
Alpha Olefin Sulfonate (AOS) is used in high-quality shampoos, light-duty liquid detergents, bubble baths, and heavy-duty liquid and powder detergents.

Alpha Olefin Sulfonate (AOS) is also used in emulsion polymerization.
C14-C16 AOS blends are frequently used in liquid hand soaps.



Alpha Olefin Sulfonate (AOS) is a pale yellow 40% aqueous solution of sodium C14-16 alpha olefin sulfonate.
Alpha Olefin Sulfonate (AOS) combines the advantages of high foaming power, good emulsification, mildness to the skin, and excellent lime soap dispersion to give the formulator maximum flexibility in the preparation of light and heavy-duty cleaners.
Alpha Olefin Sulfonate (AOS) is also suitable for use in acidic formulations such as those containing alpha hydroxyl acids or salicylic acid.
Alpha Olefin Sulfonate (AOS) is perfect for sulfate-free personal care and detergent products.


Alpha Olefin Sulfonate an anionic biodegradable aqueous solution of sodium olefin (C-14 C-16) sulfonate, is an ideal surfactant for a variety of use.
Alpha Olefin Sulfonate (AOS) can be an excellent base for all kinds of products including hand wash, shampoos, and bath products.

Alpha Olefin Sulfonate (AOS) offers formulators excellent viscosity and foam characteristics, as well as improved mildness over lauryl sulfates, can be used in variety of applications due to its excellent viscosity, hard water stability, detergency, foam characteristics.
Alpha Olefin Sulfonate (AOS) is a milder surfactant compared to lauryl sulfates and is used in high performing sulfate-free, shampoos, body wash, hand soap


Alpha Olefin Sulfonate (AOS) is a non-sulfate anionic surfactant that is commonly used in shampoos and other bath products owing to its skin-friendly properties, cleansing and foaming properties, and ability to combine well with water to remove dirt and oils.
Petroleum cracking is the most common method for producing it in large quantities.





PRODUCTION AND COMPOSITION OF ALPHA OLEFIN SULFONATE (AOS):
Alpha Olefin Sulfonate (AOS) is produced by sulfonation of alpha-olefins, typically using sulfur trioxide.
Subsequent alkaline hydrolysis gives a mixture of alkene sulfonates (60-65%) and hydroxyalkane sulfonates (35-40%).
The commercially available olefin sulfonates are mostly solutions with about 40% active ingredient content.


USAGE OF ALPHA OLEFIN SULFONATE (AOS):
Alpha Olefin Sulfonate (AOS) with linear alkenyl radicals from C12 to C18 are used as anionic surfactants in various areas of application due to their pronounced foam formation and foam stability (even with high water hardness), excellent fat-dissolving power and oil dissolving power as well as a favorable ecological profile and low aquatic toxicity and human toxicity.

They are typically used in detergents and cleaning agents, for degreasing, in the emulsion polymerization, the conditioning of concrete and mortar as well as in the formulation of pesticides.

Sodium C14-16 olefin sulfonate is being introduced in some shampoos as an alternative to sodium laureth sulfate.
Some groups and sellers suggest that it is better for someones health, but this claim lacks evidence.


Industry use:
Alpha olefin sulfonate’s primary use is in washing powder, liquid detergents, and soaps.
Other applications include the textile, printing, and dyeing industries as well as the petrochemical industry.
Alpha olefin sulfonate is additionally used as an industrial foaming agent, wetting agent, concrete density improver, and pesticide emulsifier.

Consumer use:
Alpha olefin sulfonate is commonly used as a surfactant in personal care products, such as sulfate-free shampoo, liquid and bar soaps, hand sanitizers, bath lotions, bubble baths, and facial cleansers, as well as in various household products such as dishwashing liquids and vehicle wash liquids.



APPLICATION AREAS OF ALPHA OLEFIN SULFONATE (AOS):
Alpha olefin sulfonate (AOS) is used in HI&I cleaning
Alpha olefin sulfonate (AOS) is used in Emulsion polymerization
Alpha olefin sulfonate (AOS) is used in Fire-fighting


Alpha olefin sulfonate (AOS) is used in Personal care
Alpha olefin sulfonate (AOS) is used in Laundry detergents
Alpha olefin sulfonate (AOS) is used in Industrial auxiliaries

Alpha olefin sulfonate (AOS) is used in Construction chemicals
Alpha olefin sulfonate (AOS) is used in Oil fields
Alpha olefin sulfonate (AOS) is used in Agriculture

Alpha olefin sulfonate (AOS) is used in Economical and high-performing sulfate free biodegradable shampoos
Alpha olefin sulfonate (AOS) is used in Hand soaps and shower gels

Alpha olefin sulfonate (AOS) is used in Car washing compounds
Alpha olefin sulfonate (AOS) is used in Light-duty liquid detergents
Alpha olefin sulfonate (AOS) is used in Heavy-duty laundry detergents



BENEFITS OF ALPHA OLEFIN SULFONATE (AOS):
Alpha olefin sulfonate (AOS) has Excellent cost/performance characteristics and foam properties
Alpha olefin sulfonate (AOS) has Improved mildness over lauryl sulfates
Alpha olefin sulfonate (AOS) has Excellent viscosity and foam characteristics

Alpha olefin sulfonate (AOS) is More stable than alcohol sulfates over a broad pH range
Alpha olefin sulfonate (AOS) is Fully compatible with other anionic, amphoteric and nonionic surfactants


Alpha olefin sulfonate (AOS) is mostly utilised as a major or secondary surfactant in rinse-off products such as hand washes, face washes, bubble baths, shampoos, and, most often, body washes.
Alpha olefin sulfonate (AOS) will give your DIY formulation a rich, creamy shape and make the bubbles thick and fluffy.
Because Alpha olefin sulfonate (AOS) is a natural and organic product, it'll work wonders for folks with pH-sensitive skin.

Alpha olefin sulfonate (AOS) is a fantastic substitute for sulphate products, allowing you to make a sulphate-free recipe.
Alpha olefin sulfonate (AOS) is effective with hard water.
Alpha olefin sulfonate (AOS) may be used in solid or cream goods without having to heat the solution.



HOW ALPHA OLEFIN SULFONATE (AOS) WORKS:
Alpha olefin sulfonate (AOS) cleans your skin and hair by eliminating dirt and pollutants combined with oils.
Alpha olefin sulfonate (AOS) works by enabling the oils to mingle with the water, which can then be washed away easily, effectively washing the targeted region.

CONCENTRATION AND SOLUBILITY OF ALPHA OLEFIN SULFONATE (AOS):
It is recommended that it should be used at a concentration of 10–16%.
Alpha olefin sulfonate (AOS) is soluble in water, alcohol, and glycerol but is insoluble in oil.

HOW TO USE:
Prepare the oil and water phases of your formulation separately.
Heat the oil and water phase using a double boiler.
Add our AOC to the water phase, accompanied by constant stirring.
Blend both the phases together using a mini-mixer or a large mixing brush.





STABILITY/SHELF LIFE OF ALPHA OLEFIN SULFONATE (AOS):
Two years under proper storage.
Store in a dry, cool place, away from moisture and heat.
Alpha olefin sulfonate is stable at an extensive pH range and suitable for use in acidic environments.


MANUFACTURING OF ALPHA OLEFIN SULFONATE (AOS):
Alpha olefin sulfonate is a chemical compound composed of long-chain sulfonate salts made by the process of sulfonation of alpha-olefins.
Alpha-olefin sulfonate is produced by oligomerization of ethylene, or by Fischer-Tropsch synthesis.
The process is followed by purification.


SOLUBILITY OF ALPHA OLEFIN SULFONATE (AOS):
Alpha olefin sulfonate is characterized by good solubility, suitable for use in liquid detergents.



CHEMICAL AND PHYSICAL PROPERTIES OF ALPHA OLEFIN SULFONATE (AOS):
INCI Nomenclature: Sodium C14-16 Olefin Sulfonate
Appearance: Clear Liquid: Pale Yellow to Light Amber
Suggested Use Levels: 20-60% of your entire formulation.
Suggested Applications: Clear Liquid: Pale Yellow to Light Amber
pH: 10% Aqueous 6.0
Storage: Protected from direct light and humidity at a temperature of 50°-77°F (10°-25°C)
Shelf life: 12 months from the date of manufacture
This product should be added to a formulation at the recommended usage rate.
AppearanceColorlessor light yellowliquid
Active Matter %34.0~36.0
Sulfate %≤1.36
Unsulfated Matter %1.70
NaOH %≤0.50
Color [klett]≤80




SAFETY INFORMATION ABOUT ALPHA OLEFIN SULFONATE (AOS):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product








SYNONYMS OF ALPHA OLEFIN SULFONATE (AOS):
Sodium alpha-olefin sulfonate
Sodium tetradecene sulfonate
Linear alpha-olefin
α-olefin sulfonate
Sodium a-olefin sulfonate
Sodium c14-16 olefin sulfonate



ALPHA OLEFIN SULFONATE POWDER
Alpha Olefin Sulfonate Powder Alpha olefin sulfonate powder (AOS 40%) is a formaldehyde free solution of sodium C14-C16 Alpha olefin sulfonate powder preserved with MCI/MI. It can be used in variety of applications due to its excellent viscosity, hard water stability, detergency, foam characteristics, and pH stability over a broad pH range. AOS 40% is a milder surfactant compared to lauryl sulfates and is used in high performing sulfate-free, shampoos, body wash, hand soap and pet care formulations. It is highly effective in unloading undesirable liquids and particulates from gas producing wells and exhibits exceptional thermal stability up to 400° F. This product is readily biodegradable. Univar Solutions is here to serve your Alpha olefin sulfonate powder 40% needs. With more than 120 distribution centers, our private fleet, technical expertise, and professional staff, we provide you proven reliability and quality service at every touchpoint. Alpha olefin sulfonate powder is a mild anionic surfactant with excellent viscosity and foam characteristics. It offers good solubility in water, high surface activity, enhanced detergency and foamability, compatability with all other types of surfactants, low sensitivity to water hardness, high level of biodegradability and low irritation and ecotoxicity. Alpha olefin sulfonate powder is an optimal surfactant solution for the formulation of personal care and cosmetic products, HI&I cleaning and laundry detergents. For its unique properties the product is also used in agricultural products, construction industry, fire-fighting foams etc. Description of Alpha olefin sulfonate powder: Mild anionic, high-foaming & well-emulsifying surfactant. Made primarily from coconut oils. Stable at a wide pH range and can therefore be used in acidic environments. pH: 8 (10% solution), 40% active substances. Yellowish liquid, slightly viscous, faint odor. CAS of Alpha olefin sulfonate powder: 68439-57-6 INCI Name of Alpha olefin sulfonate powder: Sodium C14-16 alpha olefin sulfonate Benefits of Alpha olefin sulfonate powder: Mild primary surfactant with excellent cleansing and degreasing properties (but non-drying on skin & mucous membranes) Good wetting effect, foam booster, slight viscosity enhancer Easily compatible with other surfactants including non-ionic, amphoteric or anionic co-surfactants Can be used for making sulfate-free cleansing products Use of Alpha olefin sulfonate powder: Can be added to formulas as is. Recommended use level is 4-30% depending on desired foaming and cleansing effects. For external use only. Applications of Alpha olefin sulfonate powder: Body washes, shampoos, bubble baths, cleansing lotions, various personal care cleansing products. Country of Origin of Alpha olefin sulfonate powder: USA Raw material source of Alpha olefin sulfonate powder: Ethylene, coconut oil Manufacture of Alpha olefin sulfonate powder: Alpha olefin suflonate is a mixture of long chain sulfonate salts prepared by the sulfonation of alpha olefins. Alpha-olefin sulfonate are produced by oligomerization of ethylene and by Fischer-Tropsch synthesis followed by purification. Animal Testing of Alpha olefin sulfonate powder: Not animal tested GMO of Alpha olefin sulfonate powder: GMO free (does not contain plant-derived components) Vegan: Does not contain animal-derived components Alpha Olefin Sulfonate powder Application of washing powder The decontamination test showed that LAS and Alpha olefin sulfonate powder showed good synergy in both phosphorous powder and phosphorus-free powder. Among the phosphorous detergent, LAS: Alpha olefin sulfonate powder has the most significant synergy at 8:2. In the non-phosphorous washing powder with LAS and Alpha olefin sulfonate powder as anionic active ingredients, the decontamination of Alpha olefin sulfonate powder increased significantly when the proportion of anionic active components was greater than 20 %. The decontamination synergy of Alpha olefin sulfonate powder in phosphorus-free washing powder is more prominent than that in phosphorous powder. Alpha olefin sulfonate powder and enzymes have better solubility. The activity of residual enzymes in detergent solutions containing domestic proteinases and imported proteinases(such as Savnase) was compared. Over time, the residual enzyme activity of anionic active groups divided into pure LAS was low. The residual enzyme activity is higher in detergent solution with Alpha olefin sulfonate powder partial replacement or all substitution of LAS. There is little difference between Alpha olefin sulfonate powder and LAS decontamination at higher temperatures and prolonged washing(eg, 60 °C or more, 1 hour washing). However, when washing at room temperature(10-40 °C, washing 10-29 minutes), Alpha olefin sulfonate powder has higher decontamination power than LAS. Compared with LAS, Alpha olefin sulfonate powder has a strong hard water resistance, so it also shows Alpha olefin sulfonate powder advantages in areas with higher hard water. LAS is superior to oil/granular decontamination, while non-ions such as fatty alcohol ether are most suitable for washing dirt and dirt on the skin. The combination of the two can achieve good decontamination effects, and Alpha olefin sulfonate powder has good decontamination effects on sebum and oily and powdery dirt. The amount of ash deposition on the fabric after washing the fabric with apatite washing powder containing 4 A zeolite, soda and soda. The phosphorous washing powder that replaces LAS with Alpha olefin sulfonate powder part is smaller than the phosphorous washing powder that uses LAS alone. After washing, the gray deposition of the fabric is small, not easy to knot, and yellowing. (reference formula) Alpha Olefin Sulfonate Application of Soap Soap produces insoluble saponin in hard water, affecting the decontamination effect. Adding Alpha olefin sulfonate powder can increase the solubility of soap in water, and the wettability and foam power of soap liquid at low temperatures also increase rapidly. Alpha olefin sulfonate powder is added to soaps with sodium adipose as the main ingredient. The various characteristics of soaps are improved, foaming force is enhanced, hard water resistance is improved, flexibility is enhanced, and cracking is not easy. Liquid Detergents Application Due to the large irritation of LAS, many washing products no longer use LAS as an active component, while Alpha olefin sulfonate powder has low irritation and good biodegradability, making it a more suitable alternative. In liquid detergents, Alpha olefin sulfonate powder has a greater influence on the viscosity of the product. The viscosity is improved with the commonly used fatty alcohol diethanolamide and Na-Cl. The effect is not ideal. The use of fatty alcohol monoethanolamide, amine oxide, betaine and NH4Cl can play a good adhesion role. Due to the characteristics of Alpha olefin sulfonate powder in decontamination, hard water resistance, viscosity, etc., Alpha olefin sulfonate powder has a wide range of applications in liquid detergents with high active components. Alpha Olefin Sulfonate Application of personal care supplies Alpha olefin sulfonate powder is as mild as AES, and LAS and AS are much larger than Alpha olefin sulfonate powder. Therefore, Alpha olefin sulfonate powder has a wide range of uses in personal care products. Alpha olefin sulfonate powder is extremely stable under acidic conditions. Normal human skin is weakly acidic(pH is about 5.5) and is suitable for using Alpha olefin sulfonate powder as a component of personal cleaning products. The shampoo with Alpha olefin sulfonate powder as the main active component is better than that with K12. Renso reported that the foam released by Alpha olefin sulfonate powder was full of cream and felt like soap when washed. This characteristic is suitable for the washing habits of Chinese people. Therefore, Alpha olefin sulfonate powder can be used in personal care products such as bath fluids, hand sanitizer and cleansing milk. Reference formula. Other Alpha Olefin Sulfonate Application Alpha olefin sulfonate powder has a wide range of applications in the textile printing and dyeing industry, petroleum chemicals, and three oil extraction and industrial cleaning. Alpha olefin sulfonate powder can be used as a concrete density modifier, foaming wall board, and fire fighting foam. It can also be used as a pesticide emulsifier, wetting agent, etc.. Application /Application Industries of Alpha olefin sulfonate powder anionic surfactant shampoo, body wash bath gel oil-displacing agent, foam boost agent for increasing oil recovery Washing powders Based on detergency test result, both LAS and Alpha olefin sulfonate powder showed good synergy in phosphorus-containing and non-phosphorus powders. In phosphate-free washing powders with LAS and Alpha olefin sulfonate powder as anionic active ingredients, the detergency of Alpha olefin sulfonate powder is significantly increased when the active content is more than 20%. The detergency synergy of Alpha olefin sulfonate powder in non-phosphorus washing powder is more oustanding than that in phosphorus-containing powder. Alpha olefin sulfonate powder has a good compatibility with enzyme. The detergency power of Alpha olefin sulfonate powder and LAS is not much different at high temperatures and long-term washing (eg above 60°C, washing for 1 hour). However, Alpha olefin sulfonate powder shows higher detergency performance than LAS when used under room temperature (10-40°C for 10-29 minutes). Compared with LAS, Alpha olefin sulfonate powder features stronger hard water resistance. Alpha olefin sulfonate powder shows a very good stain removal performance on sebum dirt and oily and powdery stain. Application of soap Adding Alpha olefin sulfonate powder can increase the solubility of soap in water, wetting power and foam strength of soap at low temperatures can also be increased significantly It improves various properties of the soap, enhances foaming power, increases hard water resistance and flexibility. Liquid detergent application Due to the greater irritation of LAS, many detergents do not use LAS as an active ingredient, while Alpha olefin sulfonate powder has a low irritative property and good biodegradability, making it a more suitable alternative. Personal care application The mildness of Alpha olefin sulfonate powder is comparable to that of AES, while LAS and AES are much more irritating than Alpha olefin sulfonate powder. Thus Alpha olefin sulfonate powder has a wide range of use in personal care products. Alpha olefin sulfonate powder is extremely stable under acidic conditions, and normal human skin is weakly acidic (pH about 5.5), so it is suitable to use Alpha olefin sulfonate powder as a component of personal washing products. Shampoos with Alpha olefin sulfonate powder as the main active ingredient are more foamable than with K12. Other applications Alpha olefin sulfonate powder has a wide range of applications in the textile printing and dyeing industry, petrochemicals, tertiary oil recovery, and industrial cleaning. It can also be used as a concrete density improver, foam wallboard, fire-fighting foaming agent. It can also be used as an emulsifier, wetting agent, etc. Examining Tomorrow’s Surfactant Personalities: Alpha Olefin Sulfonate in Personal Care Non-sulfate anionic surfactants are often used in cleansing products for personal care, hard surfaces, laundry and industrial applications. In personal care alone, they range in variety; although notably, cleansers with added hair color-retention benefits and formulas positioned for the hair, scalp and body represent the segments in highest demand. Due to these broad product applications, customizable performance attributes and biodegra­dability, the use of Alpha olefin sulfonate powder (AOS) surfactants has increased dramatically. The most common Alpha olefin sulfonate powder used in personal care is sodium C14-16 olefin sulfonate, which functions as a detergent, wetting agent and emulsifier depending on the application. When properly formulated, Alpha olefin sulfonate powder imparts viscosity, a consumer-acceptable foaming profile and quick flash foam to produce a stable lather, among other benefits. In addition, the surfactant maintains performance at alkaline and acidic ranges, allowing flexibility for formulators. This stability is attributed to the sulfonate groups covalently bonded to a carbon; conversely, sulfate-based surfactants tend to hydrolyze below pH 4 due to inorganic ester bonds that cleave and yield a sulfate anion and an alcohol. The pH stability of Alpha olefin sulfonate powder has generated additional interest over lauryl sulfates and lauryl ether sulfates for both claims and performance. Alpha olefin sulfonate powder also allows the material to be provided as a preservative-free aqueous solution, using excess alkalinity for preservation. Alpha olefin sulfonate powder (AOS) have been used successfully for many years in laundry and personal-care products throughout Asia. Among their documented positive attributes are good cleaning and high foaming in both soft and hard water, rapid biodegradability, and good skin mildness. Alpha olefin sulfonate powder has commonly been marketed as approximately 40%-active aqueous solutions. However, with the increased importance of compact powder detergents produced by processes other than spray drying, high-active forms of Alpha olefin sulfonate powder including 70%-active pastes and 90+%-active powders are now being utilized for that product sector. In this regard, the rheological properties of non-Newtonian Alpha olefin sulfonate powder and AOS/additive pastes at relevant process temperatures were measured and found potentially suitable for agglomeration processes. Also, the relationship of AOS powder particle size to surfactant solubility at various wash conditions was examined to allow determination of the optimal size for both detergency and processing of laundry powders. Both paste rheology and powder morphology are critical factors for the successful use of high-active Alpha olefin sulfonate powder in compact powder detergents. Alpha olefin sulfonate powder is a pale yellow 40% aqueous solution of sodium C14-16 alpha olefin sulfonate. Alpha olefin sulfonate powder combines the advantages of high foaming power, good emulsification, mildness to the skin, and excellent lime soap dispersion to give the formulator maximum flexibility in the preparation of light and heavy-duty cleaners. Alpha olefin sulfonate powder is also suitable for use in acidic formulations such as those containing alpha hydroxyl acids or salicylic acid. Alpha olefin sulfonate powder is perfect for sulfate-free personal care and detergent products. What Is Alpha olefin sulfonate powder? Alpha olefin sulfonate powder (Sodium C12-14 Olefin Sulfonate, Sodium C14-16 Olefin Sulfonate, Sodium C14-18 Olefin Sulfonate, Sodium C16-18 Olefin Sulfonate) are mixtures of long chain sulfonate salts prepared by the sulfonation of alpha olefins. The numbers indicate the average lengths of the carbon chains of the alpha olefins. In cosmetics and personal care products, Alpha olefin sulfonate powder are used mainly in shampoos and bath and shower products Why is Alpha olefin sulfonate powder used in cosmetics and personal care products? Alpha olefin sulfonate powder clean the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away. Alpha olefin sulfonate powder is an olefin featured by the position of solid bond (reactive unsaturation) at the two end carbons in carbon chains. Alpha olefin sulfonate powder and their derivatives are used as comonomers in polymer such as low density polyethylenes for the properties of lighter, thinner, better flexibility and more tearing resistance. Alpha olefin sulfonate powders are used in the production of linear plasticizers, oxo-alcohols, motor fuels, lubricants, automotive additives, biodegradble surfactants, paper size, and in a wide range of specialty applications in the production of mercaptans, flavors and fragrances, alkyl metals, halides, alkyl silanes. Alpha olefin sulfonate powder is used primarily as a detergent cleansing agent, but is potentially drying and can aggravate skin. Can be derived from coconut. It’s tricky to include in formulas due to stability issues, but it does produce copious foam. Alpha Olefin Sulfonate Powder CAS # 68439-57-6 & 7757-82-6 SYNONYM FORMULA CnH2n-1SO3Na (n= 14 - 16) TYPICAL PRODUCT SPECIFICATIONS ACTIVITY 90% Min. MOISTURE 2.0% Max. PH 7.0 - 10.0 (10% in water) APPEARANCE Cream colored flake at 25C COLOR 0 - 275 Klett NOTES Approximately 90 - 95% sulfonic acids, C14-16-alkane hydroxy and C14-16-alkene, sodium salts. Remaining 5-10% Sodium Sulfate. Useful as an emulsifier and foam booster in various preparations, also functions as a wetting agent. CLASS Emulsifiers, Industrial Chemicals FUNCTIONS Humectants & Emollients, Emulsifier INDUSTRY Industrial Alpha olefin sulfonate powder Select Size Deep-Cleansing Primary Surfactant Part Number: SRF-ALOS-01 Availability: In Stock Int. Shipping: HS Code 3402110000 CHOOSE OPTIONS Sizes * Quantity Share| Description Examples Description: Mild anionic, high-foaming & well-emulsifying surfactant. Made primarily from coconut oils. Water-soluble, pH: 8 (10% solution), 40% active substances. Yellowish liquid, slightly viscous, faint odor. CAS: 68439-57-6 INCI Name: Sodium C14-16 alpha olefin sulfonate Benefits: Mild primary surfactant with excellent cleansing and degreasing properties (but non-drying on skin & mucous membranes) Good wetting effect, foam booster, slight viscosity enhancer Easily compatible with other surfactants including non-ionic, amphoteric or anionic co-surfactants Can be used for making sulfate-free cleansing products Use: Can be added to formulas as is. Recommended use level is 4-30% depending on desired foaming and cleansing effects. For external use only. Applications: Body washes, shampoos, bubble baths, cleansing lotions, various personal care cleansing products. Country of Origin: USA Raw material source: Ethylene, coconut oil Manufacture: Alpha olefin sulfonate powder is a mixture of long chain sulfonate salts prepared by the sulfonation of alpha olefins. Alpha olefin sulfonate powdere are produced by oligomerization of ethylene and by Fischer-Tropsch synthesis followed by purification. Animal Testing: Not animal tested GMO: GMO free (does not contain plant-derived components) Vegan: Does not contain animal-derived components Abstract Alpha olefin sulfonate powder (AOS) have been used successfully for many years in laundry and personal-care products throughout Asia. Among their documented positive attributes are good cleaning and high foaming in both soft and hard water, rapid biodegradability, and good skin mildness. AOS has commonly been marketed as approximately 40%-active aqueous solutions. However, with the increased importance of compact powder detergents produced by processes other than spray drying, high-active forms of AOS including 70%-active pastes and 90+%-active powders are now being utilized for that product sector. In this regard, the rheological properties of non-Newtonian Alpha olefin sulfonate powder and AOS/additive pastes at relevant process temperatures were measured and found potentially suitable for agglomeration processes. Also, the relationship of Alpha olefin sulfonate powder particle size to surfactant solubility at various wash conditions was examined to allow determination of the optimal size for both detergency and processing of laundry powders. Both paste rheology and powder morphology are critical factors for the successful use of high-active Alpha olefin sulfonate powder in compact powder detergents. Key Words Alpha olefin sulfonate detergent powder surfactant Sodium Alpha-Olefin Sulfonate for Cleanser, Aos 92% Powder Get Latest Price Min. Order: 10 Tons Port: Chongqing, China Production Capacity: 500mmt/Month Payment Terms: L/C, T/T, Western Union Appearance: Powder Usage: Water Treatment Chemicals Color: White Transport Package: 25kg/Bag Trademark: UE Origin: Sichuan Contact NowRequest SampleCustomized Request Leave a message. Inquiry Basket Favorites Share Basic Info Model NO. AOS Product Description Customer Question & Answer Ask something for more details Description: It is an anionic surfactant and can be called AOS, having excellent decontamination, foaming and emulsification capacity and foaming stability; Alpha olefin sulfonate powder is extremely soluble in water and has extremely strong lime soap dispersing and softening water capacity; It has good biodegradability and is gentle to skin and has good compatibility; Products containing Alpha olefin sulfonate powder are rich in foaming, tender and feels well and easy to rinse; It can be used in matters with wide range of pH value. Sodium Alpha-Olefin Sulfonate for Cleanser, Aos 92% Powder Application: It is widely used in all kinds of lavation cosmetics such as laundry detergent, compound soap, dish washing detergent and it is the preferred raw material of non-phosphate detergent; It can be used in cleaning cosmetics such as shampoo, bath lotion and facial cleanser etc., it can also be used in industrial detergent such as oil field, mine, construction, fire protection and textile dying. Alpha olefin sulfonate powder (AOS) Sodium Alpha Olefin Sulfonate (AOS) chlick for more Other names: Alpha Olefin Sulfonate; Sodium Linear Alpha Olefin Sulfonate; Alpha olefin sulfonate powder CAS number: 68439-57-6 Molecular formula: R-CH=CH-(CH2)n-SO3Na, R=C14~1 Characteristics: Sodium alpha olefin sulfonate has the following features: 100% biodegradability Good wetting, foaming, detergency, emulsifying property Little skin irritant Good calcium soap dispersion and anti-hard water performances Dissolves in water and rinsed easily Good Stability, good compatibility with other kinds of surfactants. Alpha Olefin Sulfonates, Alpha olefin sulfonate powder, liquid AOS is a third generation surfactant having excellent properties in wetting, blending, emulsification, solubility, good stability at high temperature, and detergency. It has high foaming characteristics, mildness, less resistant to hard water and excellent bio-degradable. AOS 1416 is used for high foaming liquid detergents, high quality sampoo, soap, bubble baths and light-duty liquid detergents. AOS 1418 is used for heavy-duty laundry formulations. Alpha olefin sulfonate powder (AOS) is the sodium salt of alpha olefin sulphonate (SAOS), commonly known as Alpha olefin sulfonate powder. Alfodet L46 is a detergent active of the anionic class. Alpha olefin sulfonate powder is manufactured by continuous sulphonation of high-quality ethylene-based alpha olefins with sulphur trioxide in a specially-designed modern ‘Ballestra' continuous thin-film sulphonation reactor, followed by neutralisation and hydrolysis. Alpha olefin sulfonate powder (AOS) is an extremely light coloured liquid, thanks to efficient sulphonation, with low inorganic salt and un-sulphonated matter. No bleaching of the neutralised AOS is done after hydrolysis, ensuring that all supplies of Alfodet L46 are safe sultones within tolerable limits. Alpha olefin sulfonate powder is an effective emulsifier and has excellent foaming characteristics. Its resistance to water hardness and other metallic ions is very good, and it is stable over a wide pH range. It is superior to conventional detergent actives with regard to bio-degradability, mildness to skin, cold-water solubility, rinsability, flash foaming, and detergency in hard water. Alpha olefin sulfonate powder is compatible with other surfactants like linear alkyl benzene sulphonate (LABS) and SLS, including soap. Alpha olefin sulfonate powder helps to overcome the sting caused by conventional detergent actives. A combination of LABS and Alpha olefin sulfonate powder in certain proportions can yield synergistic detergent action, which can result in improved performance of a given total active or reduced cost for a given performance. Alpha olefin sulfonate powder (AOS) is suitable as an active for general detergent products such as detergent cakes and powders, toilet and laundry soaps, liquid detergents for fine fabrics, dish- and floor-washing liquid, woolen- and carpet-washing applications, scourers and shampoos, bubble baths and shower gels. Alpha olefin sulfonate powder liquid can replace LABS in detergent powder by incorporation at a 1.5 per cent active level or higher, depending on moisture level adjustment in the final product. Description: Mild anionic, high-foaming & well-emulsifying surfactant. Made primarily from coconut oils. Stable at a wide pH range and can therefore be used in acidic environments. pH: 8 (10% solution), 40% active substances. Yellowish liquid, slightly viscous, faint odor. CAS: 68439-57-6 INCI Name: Sodium C14-16 alpha olefin sulfonate Benefits: Mild primary surfactant with excellent cleansing and degreasing properties (but non-drying on skin & mucous membranes) Good wetting effect, foam booster, slight viscosity enhancer Easily compatible with other surfactants including non-ionic, amphoteric or anionic co-surfactants Can be used for making sulfate-free cleansing products Use: Can be added to formulas as is. Recommended use level is 4-30% depending on desired foaming and cleansing effects. For external use only. Applications: Body washes, shampoos, bubble baths, cleansing lotions, various personal care cleansing products. Country of Origin: USA Raw material source: Ethylene, coconut oil Manufacture: Alpha olefin suflonate is a mixture of long chain sulfonate salts prepared by the sulfonation of alpha olefins. Alpha-olefin sulfonate are produced by oligomerization of ethylene and by Fischer-Tropsch synthesis followed by purification. Applications Sulfate-free shampoo All purpose cleaning Bar soap Body wash Facial cleansers Hand dishwashing Vehicle wash Industrial foaming applications Commercial & household laundry Liquid hand soap Alpha Olefin Sulfonate powder 40% (Alpha olefin sulfonate powder 40%) is a formaldehyde free solution of sodium C14-C16 alpha olefin sulfonate preserved with MCI/MI. It can be used in variety of applications due to its excellent viscosity, hard water stability, detergency, foam characteristics, and pH stability over a broad pH range. Alpha Olefin Sulfonate powder 40% is a milder surfactant compared to lauryl sulfates and is used in high performing sulfate-free, shampoos, body wash, hand soap and pet care formulations. It is highly effective in unloading undesirable liquids and particulates from gas producing wells and exhibits exceptional thermal stability up to 400° F. This product is readily biodegradable. The present invention relates to a process for preparing an aqueous solution of a C14-C16 alpha olefin sulfonate, wherein the aqueous solution has a Klett color of less than 12, when diluted with water to a 5% solution. The present invention relates to a method of producing a colorless aqueous solution of an alpha olefin sulfonate which can be subsequently used in the formation of cleaning compositions. Background of the Invention Alpha olefin sulfonates are used in liquid dish cleaning compositions and hard surface cleaning compositions. Commercial alpha olefin sulfonate surfactants are usually supplied as a 35 to 45 wt. % aqueous solution. These solutions have a distinctive yellowish color which limits the use of alpha olefin sulfonate surfactant in colorless liquid cleaning compositions. The present inventions teach a method of producing a colorless aqueous solution of 35 wt. % to 45 wt. % of alpha olefin sulfonate from a commercial 35 wt. % to 45 wt. % aqueous solution of alpha olefin sulfonate which is yellowish in color. The addition of hydrogen peroxide and caustic soda to the commercially aqueous solution of the alpha olefin sulfonate causes oxidation of the containments which cause the yellowish color. Summary of the Invention The instant invention relates to a process for producing an aqueous solution of about 5 wt. % of a C-14-C1 Q alpha olefin sulfonate which has a Klett color of less than about 12, preferably less than about 11 and most preferably less than about 10. The present invention also relates to 30 to 40 wt. % solution of a C-|4-C-j6 alpha olefin sulfonate. When the 30 to 40 wt. % solution of the C14-C1 alpha olefin sulfonate is diluted with water to a 5 wt. % aqueous solution of the C-| 4-C16 alpha olefin sulfonate, the 5 wt. % solution of the C14-C1 Q alpha olefin sulfonate has a Klett color of less than about 12, more preferably less than about 11 and most preferably less than about 10. The present invention further relates to cleaning compositions having improved color. Detailed Description of the Invention The present invention relates to a process for forming a solution of 30 wt. % to 40 wt. % of a C-14-C16 alpha olefin sulfonate and 60 wt. % to 70 wt. % of water, wherein the solution, when diluted to 5 wt. %, with distilled water has a Klett color of less than 12, preferably less than 11 and most preferably less than 10 which comprises the steps of: (a) forming a solution having a pH of 10 to 12 by adding of 0.001 wt. % to 0.1 wt. % of sodium hydroxide to 99.9 wt. % to 99.999 wt. % of an initial solution of 30 wt. % to 40 wt. % of a C14-C16 alpha olefin sulfonate and 40 wt. % to 60 wt. % of water having a pH of 7.5 to 9.5, wherein said initial solution when diluted to 5 wt. % of C14- C-| β alpha olefin sulfonate has a Klett color of greater than 20; (b) adding 1 wt. % to 2 wt. % of a 25 wt. % to 35 wt. % hydrogen peroxide solution to said 30 wt. % to 40 wt. % solution of alpha olefin sulfonate; (c) mixing for 6 hours to 48 hours at 77°F to 150°F the 30 wt. % to 40 wt. % solution of C14-C15 alpha olefin sulfonate, sodium hydroxide and hydrogen peroxide, wherein said solution has a pH of about 7 to about 9; (d) adding 0.001 wt. % to 0.005 wt. % of an alkali metal hydroxide such as sodium hydroxide to said 30 wt. % to 40 wt. % solution of C14-C16 alpha olefin solution, sodium hydroxide and hydrogen peroxide to form said color improved solution of said C-| 4-C16 alpha olefin sulfonate having a pH of about 10 to about 12 which when diluted to 5 wt. % of said C14-C16 alpha olefin sulfonate has a Klett color of less than 12, preferably less than 11 , and most preferably less than 10. The present invention also relates to a solution of 30 wt. % to 40 wt. % of a C-14-C1 β alpha olefin sulfonate and 60 wt. % to 70 wt. % of water which said solution has a pH of about 10 to about 12 and when diluted to 5 wt. % of said C14-C1 Q alpha olefin sulfonate has a Klett color of less than 12, preferably less than 11 and most preferably less than 10. An object of the present invention is to provide a cleaning composition having improved color wherein said cleaning composition contains an aqueous solution of a C-|4-C-|6 alpha olefin sulfonate, wherein a 5 wt. % aqueous solution of said C-14-C15 alpha olefin sulfonate has a Klett color of less than 12, preferably less than 11 and most preferably less than 10. The present invention also relates to light duty liquid cleaning composition comprising approximately by weight: (a) 3% to 50% of a 30% to 40% aqueous solution of a C-| 4-C1 Q alpha olefin sulfonate, wherein the 30% to 40% aqueous solution of said C14-C16 alpha olefin sulfonate which has a Klett color of less than 12 when diluted with water to a 5% aqueous solution of said C14-C16 alpha olefin sulfonate; (b) 0.5% to 35% of at least one surfactant selected from the group consisting of ethoxylated nonionic surfactants, ethoxylated/propoxylated nonionic surfactant, zwitterionic surfactants, amine oxide surfactants, alkyl monoalkanol amide, paraffin sulfonate surfactants, linear alkyl benzene sulfonate surfactants, alkyl sulfate surfactants, ethoxylated alkyl ether sulfate surfactants, C-|2_Cl4 fatty acid alkanol amides, and alkyl polyglucoside surfactants and mixtures thereof. Alpha Olefin Sulfonate Application of washing powder The decontamination test showed that LAS and Alpha olefin sulfonate powder showed good synergy in both phosphorous powder and phosphorus-free powder. Among the phosphorous detergent, LAS: Alpha olefin sulfonate powder has the most significant synergy at 8:2. In the non-phosphorous washing powder with LAS and Alpha olefin sulfonate powder as anionic active ingre
ALPHA OLEFIN SULPHONATE
Alpha Olefin Sulphonate, or α-Olefin sulfonates, commonly called AOS for short, is a third-generation anionic surfactant.
Alpha Olefin Sulphonate's biodegradable, mild, and resistant to hard water, yet with outstanding detergency and excellent compatibility with other types of surfactants.


CAS Number: 68439-57-6
EC Number: 270-407-8
Classification: Anionic surfactant
INCI Name:Sodium C14-16 Olefin Sulfonate
Chemical Formula: C14H27NaO3S


In its raw form, Alpha Olefin Sulphonate has the look of a fine white powder.
The chemical formula of Alpha Olefin Sulphonate is C14H27NaO3S.
There are commonly two types of Alpha Olefin Sulphonate commercially available, the liquid solution(with 33%-40% active matter content) and the dry powder(with 85%-95% active matter content).


The manufacturing process for Alpha Olefin Sulphonate involves the sulfonation of the α-olefin selected to create the final surfactant.
Alpha Olefin Sulphonate is the most common olefin used for synthesis in personal care applications due to its stable foam production and detergency for the final Alpha Olefin Sulphonate.


The sulfonation process may be carried out with different types of sulfonating agents, such as bisulfites or sulfur trioxide (SO3).
The use of bisulfites introduces the bisulfite ion into the olefinic double bond in the presence of an oxidant, yielding an alkyl sulfonate.
The normally linear C-chain in alkene 1-sulfonates and hydroxyalkane 1-sulfonates may contain 11 to 20 carbons with 14 to 18 carbons as the usual range.


Alpha Olefin Sulphonate is a common surfactant.
The bisulfate process, however, is not suitable for commercial production due to low yields and the complexity involved in the process.
The SO3 used for the reaction is commonly derived from the oxidation (burning) of sulfur.


SO3 may also be recovered from oleum stripping or stabilized sulfur trioxide; however, stabilized SO3 requires removal of the stabilizer prior to reaction, adding an additional manufacturing step.
Alpha Olefin Sulphonate is stable.


The principal sulfonation method to produce Alpha Olefin Sulphonate is a continuous process called falling film sulfonation, where a thin film of α-olefin is contacted with gaseous SO3 to create olefin sulfonic acid.
Alpha Olefin Sulphonate is an economical and versatile Biodegradable surfactant.


Alpha Olefin Sulphonate is a mild solid anionic surfactant made from coconut oil.
Typical manufacturing steps to produce Alpha Olefin Sulphonate are comprised of α-olefin sulfonation, free-oil digestion, neutralization and hydrolysis.
Sulfonation reaction temperatures are controlled by feedingAlpha Olefin Sulphonate into the reactor as a thin film while moderating contact of the gaseous


SO3 vapor using an inert gas between the reactants.
Variations in the reactant feed rate, contact time, temperature of addition and mole ratio (SO3:α-olefin) affect the quality, including color, byproduct levels and free-oil levels.


Alpha Olefin Sulphonate consists chiefly of sodium alkene sulfonates and sodiumhydroxyalkane sulfonates.
Alpha Olefin Sulphonate is odourless.
Significant differences can result depending on the process equipment and controls.


The process is run continuously to handle production volumes and for finer control.
Alpha Olefin Sulphonate does not cause environmental problems and is biodegradable.
Alpha Olefin Sulphonate is a versatile and biodegradable cleansing agent with high cleaning power and strong foaming properties.


Unfortunately, these two properties for a surfactant usually mean that it is harsh on the skin, which is the case here as well.
The ratio of alkenesulfonate to n-hydroxyalkanesulfonate is also impactful due to their solubility differences and can impact minimum storage conditions of approximately 20–27°C.


The chemical formula of Alpha Olefin Sulphonate is C14H27NaO3S.
Alpha Olefin Sulphonate provides excellent foam and is stable over a wide pH range.
Alpha Olefin Sulphonate is a safe substance in accordance with applicable chemical regulations.


The presence of the -OH group in the hydroxyalkane sulfonate structure increases solubility and lowers surface activity significantly more than the presence of unsaturation in the alkene sulfonate.
Alpha Olefin Sulphonate’s an anionic or negatively charged surfactant that offers mild cleansing.


Alpha Olefin Sulphonate is a high active anionic surfactant with excellent viscosity and flash foaming characteristics with improved mildness in comparison to lauryl sulphates.
Alpha Olefin Sulphonate is an aqueous solution of alpha Alpha Olefin Sulphonate which is produced by the continuous sulfonataion of alpha olefins via


Alpha Olefin Sulphonate consist of a mixture of alkene sulfonates (about 60-65%) and hydroxyalkane sulfonates (about 30-40%).
Alpha Olefin Sulphonate is a common surfactant.


The most common Alpha Olefin Sulphonate used in personal care is sodium C14-16 olefin sulfonate, which functions as a detergent, wetting agent and emulsifier depending on the application.
Alpha Olefin Sulphonate does not show an allergic effect.


Alpha Olefin Sulphonate is soluble in water.
Alpha Olefin Sulphonate may be produced from several olefins with differing performance characteristics.
Typical grades are derived from C14-16, C16-18 and C14-18, and vary in product applications.


Lower molecular weight grades are more soluble and produce better foam, while those with higher molecular weights have reduced solubility and increased detergency.
Alpha Olefin Sulphonate is an anionic surfactant that is derived from coconut oil.


Therefore, Alpha Olefin Sulphonate of two different grades could lead to performance differences in apparently similar products with all other ingredients held constant.
Alpha Olefin Sulphonate can more effectively remove dirt and deposits from the hair.


Foam volume, density and viscosity also vary depending on parent olefin carbon chain lengths and ratios.
Alpha Olefin Sulphonate is yellowish liquid, slightly viscous liquid
Alpha Olefin Sulphonate can be added to formulas as is. Recommended use level of Alpha Olefin Sulphonate is 4-30% depending on desired foaming and cleansing effects.


Alpha Olefin Sulphonate is an anionic surfactant that is derived from coconut oil.
Alpha Olefin Sulphonate has excellent wetting properties.
Alpha Olefin Sulphonate is mild anionic, high-foaming & well-emulsifying surfactant.


Alpha Olefin Sulphonate has high efficiency both in terms of cleaning and foaming.
Alpha Olefin Sulphonate consists chiefly of sodium alkene sulfonates and sodiumhydroxyalkane sulfonates.
Alpha Olefin Sulphonate is stable at a wide pH range and can therefore be used in acidic environments.


Alpha Olefin Sulphonate is the sodiumsalt of alpha olefin sulphonate (SAOS), commonly known as AOS.
Alpha Olefin Sulphonate has an excellent properties in wetting, blending, emulsification, solubility, good stability at high temperature, and detergency.
Alpha Olefin Sulphonate has high foaming characteristics, mildness, less resistant to hard water and excellent bio-degradable.


Alpha Olefin Sulphonate is an anionic surfactant providing excellent viscosity, foam characteristics and mildness.
Alpha Olefin Sulphonate is a pale yellow to light amber aqueous solution that is highly soluble in water.
These surfactants provide outstanding detergency, high compatibility with hard water, and good wetting and foaming properties.


Alpha Olefin Sulphonate is free of skin irritants and sensitizers, and it biodegrades rapidly.
Alpha Olefin Sulphonate is made up of a long chain of sulfonate salts that are prepared by the by-sulfonation of C14-16 olefins.
Alpha Olefin Sulphonate is a coconut-based surfactant that offers good cleansing and excellent foaming abilities.


Alpha Olefin Sulphonate is an anionic biodegradable aqueous solution of sodium olefin (C-14 C-16) sulfonate.
The chemical formula of Alpha Olefin Sulphonate is C14H27NaO3S.
Alpha Olefin Sulphonate is an ideal surfactant for a variety of use.


Alpha Olefin Sulphonate is a mild anionic surfactant with excellent viscosity and foam characteristics.
Alpha Olefin Sulphonate offers good solubility in water, high surface activity, enhanced detergency and foamability, compatability with all other types of surfactants, low sensitivity to water hardness, high level of biodegradability and low irritation and ecotoxicity.


Alpha Olefin Sulphonate is mostly derived from coconut oils.
Alpha Olefin Sulphonate is a mixture of long chain sulfonate salts prepared by sulfonation of C14-16 alpha olefins.
Alpha Olefin Sulphonate is a great surfactant that helps remove dirt, pollutants and buildup from the hair and scalp.


Alpha Olefin Sulphonate is typically created by processes such as ethylene oligomerization, or by the Fischer-Tropsch process of synthesis.
Alpha Olefin Sulphonate is anionic surfactants with a high cleansing and degreasing effect.
Alpha Olefin Sulphonate primarily consists of sodium hydroxy alkane sulfonates and sodium alkene sulfonates.


The sulphonation process starts inside a continuous thin film reactor.
High-temperature hydrolysis reacts with sultones to form a mixture of cyclic sulfonate esters and alkene sulfonic acids.
This is followed by incorporating aqueous sodium hydroxide to neutralize the mix.


Neutralization and hydrolysis are carried out in isopropanol instead of water in order to form Alpha Olefin Sulphonate in solid form.
The most common Alpha Olefin Sulphonate used in cosmetics is sodium C14-16 olefin sulfonate.
This multifunctional variety can act as a detergent, emulsifier, and wetting agent.


Alpha Olefin Sulphonate is made up of a long chain of sulfonate salts that are prepared by the by-sulfonation of C14-16 olefins.
Alpha Olefin Sulphonate primarily consists of sodium hydroxy alkane sulfonates and sodium alkene sulfonates.
Alpha Olefin Sulphonate contains sulfur, but does not contain sulfates.


Alpha Olefin Sulphonate is an anionic surfactant produced by sulfonation of α-alkene by SO3.
Alpha Olefin Sulphonate can be an excellent base for all kinds of products including hand wash, shampoos, and bath products.
Properly formulated, Alpha Olefin Sulphonate enhances viscosity, foaming properties, and the production of a stable lather.


Alpha Olefin Sulphonate is biodegradable anionic surfactant with excellent flash foam that performs well over a wide pH range.
Alpha Olefin Sulphonate is a high active anionic surfactant with excellent viscosity and flash foaming characteristics with improved mildness in comparison to lauryl sulphates.


The concentration of Alpha Olefin Sulphonate depends on desired properties, such as foaming and cleansing effects.
Alpha Olefin Sulphonate is an economical and versatile Biodegradable surfactant.
Alpha Olefin Sulphonate is a mild anionic, high-foaming & well-emulsifying surfactant.


Alpha Olefin Sulphonate stores in a dry, cool place, away from moisture and heat.
Alpha Olefin Sulphonate can be added to formulas on its own, in a range of 4-30% of the final product.
Alpha Olefin Sulphonate is a formaldehyde-free solution of sodium C14-C16 alpha olefin sulfonate preserved with MCI/MI.


Alpha Olefin Sulphonate is a mixture of long chain sulfonate salts prepared bysulfonation of C14-16 alpha olefins.
In its raw form, Alpha Olefin Sulphonate has the look of a fine white powder.
Alpha Olefin Sulphonate is a sodium sulfonate salt.


Alpha Olefin Sulphonate (also: alpha-olefin sulfonates or AOS) are a group of anionic surfactants, which are used as detergents.
Alpha Olefin Sulphonate contains a - mostly linear, primary - alkyl R and a monovalent cation M, preferably sodium.
The most frequently used example of Alpha Olefin Sulphonate of substances is sodium α-olefin sulfonate (INCI: Sodium C14-16 Olefin Sulfonate).


The numbers indicate the average lengths of the carbon chains of the alpha olefins.
Alpha Olefin Sulphonate is mixtures of long chain sulfonate salts prepared by the sulfonation of alpha olefins.
Alpha Olefin Sulphonate can function as a primary or complimentary cleansing surfactant in all kinds of formulations.


In addition to a longer hydrocarbon chain in which there must be at least one double bond (hence the name "olefin"), Alpha Olefin Sulphonate has an anionic sulfonate headgroup with a sodium ion as a counterion.
The sulfonate group is negative in an aqueous solution, which is why the Alpha Olefin Sulphonate is among the anionic surfactants.


Alpha Olefin Sulphonate is a great surfactant that helps remove dirt, pollutants and buildup from the hair and scalp.
In contrast to most other surfactants in which the C12-alkyl chains have the highest surface activity, olefin sulfonates shows maximal activity when using C14and C16-olefins.


Alpha Olefin Sulphonate is an anionic surfactant providing excellent viscosity, foam characteristics and mildness.
Alpha Olefin Sulphonate is a mixture, alkenyl sulfonate is the main component of AOS, accounting for about 70%, hydroxyalkyl sulfonate accounts for about 30%, in addition, there are alkenes containing 2 sulfonic acid groups Disulfonate, accounting for about 0~5%.
Alkene sulfonates have a structure represented as H3C(CH2)mCH=CH(CH2)n-SO3.Na+; m=1,2,3..; n= 0,1,2,...; m+n=9-15


Alpha Olefin Sulphonate is an anionic surfactant that is derived from coconut oil.
Alpha Olefin Sulphonate is made up of a long chain of sulfonate salts that are prepared by the by-sulfonation of C14-16 olefins.
Alpha Olefin Sulphonate primarily consists of sodium hydroxy alkane sulfonates and sodium alkene sulfonates.



USES and APPLICATIONS of ALPHA OLEFIN SULPHONATE:
Alpha Olefin Sulphonate has a very mild moisturizing and emulsifying effect, has strong wetting properties and enhances the foaming.
Alpha Olefin Sulphonate is an anionic surfactant often found in bath, shower, and hair care cleansers.
Mostly present in hair care products, Alpha Olefin Sulphonate can also be used in skin care and cosmetics.


Alpha Olefin Sulphonate is a mixture of long chain sulfonate salts prepared by sulfonation of C14-16 alpha olefins.
Alpha Olefin Sulphonate is a cleaning agent, or "surfactant," that can also be found in shampoos, shower products and cleaners.
Alpha Olefin Sulphonate, or AOS 40%, is an environmentally friendly, biodegradable, aqueous solution of sodium C14-16 alpha Alpha Olefin Sulphonate.


Alpha Olefin Sulphonate is used Bathroom Cleaning, Liquid soap, Shampoo, and Toilet Block.
However, Alpha Olefin Sulphonate is a mixture of different components, and its performance and safety will vary with the changes of synthetic raw materials, synthesis equipment and synthesis conditions.


Alpha Olefin Sulphonate is derived from coconut and produces a copious foam.
The name may be misleading, but Alpha Olefin Sulphonate is not a sulfate.
Sulphonate is related to but not the same as sulfates.


Alpha Olefin Sulphonate is an excellent choice for manufacturing economical, high performing sulfate-free, biodegradable shampoo and body wash formulas, hand soaps, pet care formulations, even works exceptionally well in industrial and household cleaners, and car and truck wash products.
In a sulfonate the sulfur is linked direct to a carbon atom where as a sulfate is linked directly to the carbon chain via an oxygen atom.


They do have similar qualities when it comes to propensity of being irritating to the skin but Alpha Olefin Sulphonate is not a sulfate.
Alpha Olefin Sulphonate has great flash foam – making it great for inclusion in bubble baths – good lather, and good bubbles.
Alpha Olefin Sulphonate works tremendously well.


A rather strong cleansing agent with the ability for high foaming and a well-emulsifying surfactant.
Alpha Olefin Sulphonate is an ideal surfactant for a variety of HI&I cleaning and personal care applications, agricultural formulations, and construction products used for concrete bases, firefighting foams and dust control.


Alpha Olefin Sulphonate is safe for use in for personal care products that mixes well with water to remove dirt, oils, and pollutants so they can be rinse away.
This popular surfactant, also known as Alpha Alpha Olefin Sulphonate liquid offers the advantages of high foaming power, good emulsification, skin mildness and excellent lime soap dispersion.


This is an excellent addition to clarifying shampoos and to be used in bath-bombs.
Alpha Olefin Sulphonate can be used in industrial detergents.
Alpha Olefin Sulphonate is more stable than alcohol sulfates over a broad pH range.


Alpha Olefin Sulphonate is used High-quality shampoos, light-duty liquid detergents, bubble baths, and heavy-duty liquid and powder detergents, emulsion polymerization, etc.
Alpha Olefin Sulphonate is used primarily as a detergent cleansing agent, but is potentially drying and can aggravate skin.


Foam benefits also are noted in conjunction with betaines and ethoxylated glucosides, which have synergy with Alpha Olefin Sulphonate and improve foam quality.
Alpha Olefin Sulphonate is a fairly good cleaner with high foaming capabilities that emulsifies very well.


Alpha Olefin Sulphonate is an anionic surfactant.
Alpha Olefin Sulphonate is widely used in a variety of washing and cosmetics: used as the main raw material for washing powder, complex soap, dishwashing detergent, non-phosphorus detergent.


Although higher surfactant loads of Alpha Olefin Sulphonate are generally necessary to achieve enhanced foaming profiles, the moderate cost for C14-16 olefin sulfonate offsets the need for higher concentrations.
Alpha Olefin Sulphonate can be an excellent base for all kinds of popular products including hand soaps, shampoos, and bath products.


Levels also can be reduced when used in combination with ethoxylated glucosides, fatty alkanomides or fatty amidoalkyl betaines, which increase foam abundance stability and create a wetter foam for a creamier lather.
Alpha Olefin Sulphonate improves the interlinking of the components in the product, i.e. its consistency and flexibility.


Alpha Olefin Sulphonate is added to plenty of hair care and skin care products such as shampoos and cleansers.
Alpha Olefin Sulphonate is a strong detergent used in thorough cleansing shampoos.
Alpha Olefin Sulphonate is also readily biodegradable and won't over-dry skin by stripping natural oils.


Alpha Olefin Sulphonate offers formulators excellent viscosity and foam characteristics, as well as improved mildness over lauryl sulfates.
The ability of Alpha Olefin Sulphonate-based formulations to be customized for performance with common secondary ingredients allows product developers to readily meet design and cost targets for various segments; e.g., economy, mass, premium and luxury.


Alpha Olefin Sulphonate is used as detergent for washing powder, composite soap, tableware detergent, and the preferred main raw material of phosphorus free detergent.
Alpha Olefin Sulphonate is the choice for sulfate-free personal care and detergent products.


Alpha Olefin Sulphonate is used Washing Machine Detergent, Shower Gel, Hand & Body Care, Hand Washing Liquid, General cleaning, Liquid soap, Shampoo, and Oil Remover.
Further comparisons of Alpha Olefin Sulphonate is commonly used surfactants.


Alpha Olefin Sulphonate can be widely used in phosphate-free washing powder, liquid detergents and other household cleaning products and textile printing and dyeing industry, petroleum chemicals, industrial hard surface cleaning aspect.
At the same time, Alpha Olefin Sulphonate has stronger detergency when used with auxiliaries, and has broad application prospects.


Alpha Olefin Sulphonate’s good with hard water or soap.
Alpha Olefin Sulphonate can be used in shampoo, shower gel, facial cleanser and other cleaning cosmetics, as well as industrial detergent.
Alpha Olefin Sulphonate is anionic surfactant and foaming agent.


Alpha Olefin Sulphonate combines the advantages of high foaming power and good emulsification to make excellent industrial cleaners and car wash products.
As stated, the chemical stability of Alpha Olefin Sulphonate and its ability to maintain efficacy under extremes of pH enable broad applications.
Alpha Olefin Sulphonate is suitable for use in clarifying shampoo formulas (shampoos that focus on cleaning efficiency which can wash everything that sticks on the hair), liquid soap for athletes / people who sweat a lot.


The low pH stability of Alpha Olefin Sulphonate has advantages over sulfates in specialized products for anti-acne treatments that contain large amounts of salicylic acid.
Alpha Olefin Sulphonate is an anionic surfactant, a wide variety of cosmetic washing, hand-washing liquid, washing powder, complex soap, shampoo and detergent, phosphate-free detergents and other main raw material of choice.


And again, this flexibility also allows for alkaline preservation, alleviating concerns over preservative type and regulatory restrictions.
Alpha Olefin Sulphonate is used Air Drilling, All Purpose Cleaners, Car Wash Soap, Concrete Foamer, Detergents, Dishwash Detergents, Fire Fighting Foam, Green Products, and Laundry Detergents.


Alpha Olefin Sulphonate can be derived from coconut; it is used primarily as a detergent cleansing agent.
Alpha Olefin Sulphonate is used in products to remove dirt and deposits by surrounding dirt particles to loosen them from the surface they're attached to, so they can be rinsed away.


All in all, Alpha Olefin Sulphonate can be effectively formulated in synergy with secondary surfactants and electrolytes to meet consumer-acceptable viscosity, aesthetics and foam quality.
Alpha Olefin Sulphonate is an ideal surfactant for a variety of HI&I cleaning and personal care applications, agricultural formulations, and construction products used for concrete bases, firefighting foams and dust control.


Alpha Olefin Sulphonate's moderate price can positively impact associated formulation costs due its versatility and broad application.
In addition to the cosmetic industry, Alpha Olefin Sulphonate is used in agriculture, in the textile industry, in detergents, in the construction industry, and is added to fire-fighting foams.


Alpha Olefin Sulphonate is also readily biodegradable, which is a highly desirable feature.
Alpha Olefin Sulphonate has washing component with very good foaming properties.
Alpha Olefin Sulphonate mainly be used in mild detergent and products for baby, such as hand lotion, washing powder, complex soap, shampoo, bath lotion, facial cleaning cream, phosphorus free detergent.


Alpha Olefin Sulphonate has good surface and interfacial activity, salt resistance, and is less irritating, safe to the environment and human body, and has been widely used in detergents, skin cleaning products, tertiary oil recovery and industrial cleaning.
Taken together, the robust nature of Alpha Olefin Sulphonate, cost in use and tangible benefits as well as claims have advantages for use in the future development of personal care products.


Alpha Olefin Sulphonate has a pH of 9 to 10, which is alkaline and needs to be reduced for products used on hair or skin, but is fine for bubble baths or bath bombs.
In cosmetics and personal care products, Alpha Olefin Sulphonate is used mainly in shampoos and bath and shower products.


Cosmetic Uses of AAlpha Olefin Sulphonate: cleansing agents, foaming agents, surfactants, Dishwashing detergents, liquid detergents, shampoos and body shampoos.
Alpha Olefin Sulphonate is added to plenty of hair care and skin care products such as shampoos and cleansers.


Alpha Olefin Sulphonate provides excellent foam and is stable over a wide pH range.
Alpha Olefin Sulphonate is more stable than alcohol sulfates over a broad pH range.
Alpha Olefin Sulphonate is used primarily as a detergent cleansing agent.


Alpha Olefin Sulphonate is surfactants with high detergency, very high wetting, and foaming properties that are compatible with the hard water often found in India.
Alpha Olefin Sulphonate can also be used as industrial detergents.


When you apply a product with Alpha Olefin Sulphonate in it, the chemical will actually dig out the pollutants in your follicles to be washed away easily with water.
Alpha Olefin Sulphonate can be derived from coconut.


Alpha Olefin Sulphonate is more effective at getting rid of the dirt and buildup on your hair.
Since Alpha Olefin Sulphonate is used in both wet and dry formulations, paste, noodles, powder or needles.
Alpha Olefin Sulphonate can be used to make Bath Bombs.


Alpha Olefin Sulphonate cleans the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away.
Alpha Olefin Sulphonate is for dust control as well as shampoos, hand soaps, bath products, and carpet foamer.
Alpha Olefin Sulphonate can be used in shampoo, shower gel, facial cleanser and other cleaning cosmetics, as well as industrial detergent.


Alpha Olefin Sulphonate's widely used to formulate high-foaming heavy-duty detergent as the secondary surfactant alone with Linear Alkyl Benzene Sulphonic Acid (LABSA) or to formulate mild light-duty detergents and personal care products, such as hand soap liquid, shampoo, baby bubble bath, and so on.
Alpha Olefin Sulphonate is alkali is a highly active, spray-dried material with excellent wetting, foaming and cleaning properties in acid or neutral medium and in the presence of metallic salts usually found in hard waters.


As noted, there are several benefits to formulating with Alpha Olefin Sulphonate, including broad pH stability and formulation versatility.
Alpha Olefin Sulphonate also has been used for hard surface detergent and personal care products, and is developing it in oil additives, starch processing aid, acrylate emulsion, mercerized cotton, wool washing, textile and paper wetting like applications in the field.


Alpha Olefin Sulphonate can be used as a primary surfactant in combination with betaines or sarcosinates, as well as nonionic surfactants such as polyglucoside and polysorbate and other nonionic derivatives.
Alpha Olefin Sulphonate is used in cosmetics as an anionic surfactant, it produces abundant foam.


When Alpha Olefin Sulphonate is used in a shampoo, these are surface-active agents that emulsify the dirt and oils on your hair and scalp.
Alpha Olefin Sulphonate is an anionic surfactant, a wide variety of cosmetic washing, hand-washing liquid, washing powder, complex soap, shampoo and detergent, phosphate-free detergents and other main raw material of choice.


The nonionic surfactants aid in building sufficient packing of the micelles in the systems, consequently increasing the viscosity.
Alpha Olefin Sulphonate also has been used for hard surface detergent and personal care products, and is developing it in oil additives, starch processing aid, acrylate emulsion, mercerized cotton, wool washing, textile and paper wetting like applications in the field.


Salt also can be used to enhance the thickening of the system; however, when using NH4Cl in place of NaCl, the product pH must be less than 7.0 to prevent ammonia formation and off odor.
Alpha Olefin Sulphonate widely used in all kinds of washing and cosmetic products.


Alpha Olefin Sulphonate has excellent wettability, foaming power and emulsifying power.
In addition, Alpha Olefin Sulphonate maintains performance at alkaline and acidic ranges, allowing flexibility for formulators.
Alpha Olefin Sulphonate is added to personal and hair care products, in which it is especially suitable for curly hair.


Alpha Olefin Sulphonate can be used in concentrations of 4-30% depending on desired foaming and cleansing effects.
Alpha Olefin Sulphonate has excellent wettability, decontamination power, foaming power and emulsifying power; it is easy to dissolve in water, has strong calcium soap dispersing power and hard water resistance; it has good biodegradability, mild to skin, and good compatibility.


This stability is attributed to the sulfonate groups covalently bonded to a carbon; conversely, sulfate-based surfactants tend to hydrolyze below pH 4 due to inorganic ester bonds that cleave and yield a sulfate anion and an alcohol.
Alpha Olefin Sulphonate can be widely used in phosphate-free washing powder, liquid detergents and other household cleaning products and textile printing and dyeing industry, petroleum chemicals, industrial hard surface cleaning aspect.


The pH stability of Alpha Olefin Sulphonate has generated additional interest over lauryl sulfates and lauryl ether sulfates for both claims and performance.
Alpha Olefin Sulphonate is used detergent high efficiency both in terms of cleaning and foaming, suitable for use in clarifying shampoo formulas , Liquid soap for athletes / those who sweat a lot.


Alpha Olefin Sulphonate is often used in cleansing products for personal care, hard surfaces, laundry and industrial applications.
In personal care alone, Alpha Olefin Sulphonate ranges in variety; although notably, cleansers with added hair color-retention benefits and formulas positioned for the hair, scalp and body represent the segments in highest demand.


Due to these broad Alpha Olefin Sulphonate applications, customizable performance attributes and biodegradability, the use of Alpha Olefin Sulphonate surfactants has increased dramatically.
When properly formulated, Alpha Olefin Sulphonate imparts viscosity, a consumer-acceptable foaming profile and quick flash foam to produce a stable lather, among other benefits.


As noted, variations in olefin quality will transfer into the final composition, and may cause differences in foam volume, density wetting properties and viscosity due to effects on surfactant micelle packing.
For example, long, single-branching and random internal olefin bonds from the Oxo pathway may result in reduced surface activity in the final sulfonate product.


Alpha Olefin Sulphonate is used primarily as a detergent cleansing agent.
Alpha Olefin Sulphonate can be used for making sulfate-free cleansing products.
Alpha Olefin Sulphonate is a versatile and biodegradable cleansing agent with high cleaning power and strong foaming properties.


Alpha Olefin Sulphonate is easy to dissolve in water, has strong calcium soap dispersing power and hard water resistance.
Alpha Olefin Sulphonate is used for external use only.
Alpha Olefin Sulphonate is used body washes, shampoos, bubble baths, cleansing lotions, various personal care cleansing products.


Texture uses of Alpha Olefin Sulphonate: Slippery, detergenty
Scent uses of Alpha Olefin Sulphonate: Characteristically detergent
Alpha Olefin Sulphonate is used mild primary surfactant with excellent cleansing and degreasing properties (but non-drying on skin & mucous membranes)


Alpha Olefin Sulphonate is used Primary surfactant, Detergent & foaming.
Alpha Olefin Sulphonate has good biodegradability, mild to skin, and good compatibility.
Alpha Olefin Sulphonate is used in various household and industrial applications such as concrete foamer.


Alpha Olefin Sulphonate’s tricky to include in formulas due to stability issues, but it does produce copious foam.
Alpha Olefin Sulphonate is used Fantastic lather, great cleansing.
Alpha Olefin Sulphonate also allows the material to be provided as a preservative-free aqueous solution, using excess alkalinity for preservation.


Alpha Olefin Sulphonate’s tricky to include in formulas due to stability issues, but it does produce copious foam.
Alpha Olefin Sulphonate is an ideal surfactant for a variety of detergent and personal care applications including hand soaps, shampoos, and bath products.
Alpha Olefin Sulphonate is used in high-quality shampoos and light-duty liquid detergents.


Alpha Olefin Sulphonate is mild primary surfactant with excellent cleansing and degreasing properties.
Alpha Olefin Sulphonate is also used in bubble baths, and heavy-duty liquid and powder detergents.
Alpha Olefin Sulphonate offers the formulator excellent viscosity and foam characteristics, as well as improved mildness over lauryl sulfates.


Unfortunately, these two properties for a surfactant usually mean that Alpha Olefin Sulphonate is harsh on the skin, which is the case here as well.
Alpha Olefin Sulphonate is a pretty effective cleansing agent with good foaming properties.
Compared to petroleum-based or suflate surfactants, Alpha Olefin Sulphonate performs well, without the negative effects associated with petro-chemical based products and sulfates.


Alpha Olefin Sulphonate is used in our Body Washes.
Alpha Olefin Sulphonate is also used in emulsion polymerization.
If you’re looking for an adequate cleanser, your best option is to use Alpha Olefin Sulphonate, which is an anionic surfactant derived from coconut.


Alpha Olefin Sulphonate is one of the strongest detergents, thoroughly cleans and degreases.
Due to its strong action, Alpha Olefin Sulphonate is often found in a group with amphoteric detergents, soothing its effect.
Alpha Olefin Sulphonate offers good cleansing and flash-foam properties, giving our body washes full, cushioning lather.


Alpha Olefin Sulphonate is used for shampoo, body wash, facial cleanser and other cleaning cosmetics.
As it’s great for removing sebum gently, Alpha Olefin Sulphonate’s great for normal to oily hair or skin.
Alpha Olefin Sulphonate works well as a cleansing, foaming, and dispersing agent in HI&I and cosmetics.


Alpha Olefin Sulphonate is less irritating, safe to human body, has good biodegradability, wettability, solubility, calcium soap dispersibility and good compatibility with zeolite.
Alpha Olefin Sulphonate is widely used in all kinds of washing and cosmetic products.


Alpha Olefin Sulphonate has low ecotoxicity, it is used in cosmetics only in moderate concentrations.
Alpha Olefin Sulphonate is used as detergent for washing powder, composite soap, tableware detergent, and the preferred main raw material of phosphorus free detergent.


Mostly present in hair care products, Alpha Olefin Sulphonate can also be used in skin care and cosmetics.
Alpha Olefin Sulphonate has excellent surface activity, foaming properties, mildness to skin, and good synergy with alkaline protease, making it suitable for use in dishwashing detergents, shampoos, hair dyes and other daily use Chemicals.


Alpha Olefin Sulphonate is used in high-quality shampoos, light-duty liquid detergents, bubblebaths, and heavy-duty liquid and powder detergents.
Alpha Olefin Sulphonate offers formulators excellent viscosity and foam characteristics, as well as improved mildness over lauryl sulfates.
Alpha Olefin Sulphonate can be used in variety of applications due to its excellent viscosity, hard water stability, detergency, foam characteristics.


Alpha Olefin Sulphonate is a milder surfactant compared to lauryl sulfates and is used in high performing sulfate-free, shampoos, body wash, hand soap.
Alpha Olefin Sulphonate is an optimal surfactant solution for the formulation of personal care and cosmetic products, HI&I cleaning and laundry detergents.
For its unique properties Alpha Olefin Sulphonate is also used in agricultural products, construction industry, fire-fighting foams etc.


This amber-colored liquid, Alpha Olefin Sulphonate, is derived from petroleum and is used as a surfactant to produce highly foaming, exceptionally mild shampoos, soaps, handwashes, detergents, cleansing lotions, etc.
Alpha Olefin Sulphonate's excellent cleaning and degreasing properties make it ideal for application in the textile industry.


Alpha Olefin Sulphonate mainly be used in mild detergents and products for baby, such as hand lotion, washing powder, complex soap, shampoo, bath lotion, facial cleaning cream, phosphorus-free detergent.
Alpha Olefin Sulphonate can also be used as industrial detergents.


Alpha Olefin Sulphonate features excellent cleaning and degreasing properties, strong wetting effect, foam booster, slight viscosity enhancer.
Alpha Olefin Sulphonate’s compatible with other surfactants, including amphoteric and non-ionic co-surfactants.
Alpha Olefin Sulphonate’s gentle on the skin, without drying effects, which makes it ideal for making sulfate-free cleansing products.


Those features, along with decent biodegradability, lead to the high popularity of Alpha Olefin Sulphonate as a cosmetic ingredient.
In general, non-sulfate anionic surfactants are gradually becoming the prime solution for use in personal care cleansing products, particularly for scalp and hair care.


Alpha olefin sulfonate is stable at an extensive pH range and suitable for use in acidic environments.
Alpha Olefin Sulphonate is commonly used as a surfactant in personal care products, such as sulfate-free shampoo, liquid and bar soaps, hand sanitizers, bath lotions, bubble baths, and facial cleansers, as well as in various household products such as dishwashing liquids and vehicle wash liquids.


Alpha Olefin Sulphonate is characterized by good solubility, suitable for use in liquid detergents.
Alpha Olefin Sulphonate is a great surfactant that helps remove dirt, pollutants and buildup from the hair and scalp.
Mostly present in hair care products, Alpha Olefin Sulphonate can also be used in skincare and cosmetics.


Alpha Olefin Sulphonate is a pretty effective cleansing agent with good foaming properties.
Alpha Olefin Sulphonate is added to plenty of hair care and skin care products such as shampoos and cleansers.
Alpha Olefin Sulphonate can be used in variety of applications due to its excellent viscosity, hard water stability, detergency, foam characteristics, and pH stability over a broad pH range.


Alpha Olefin Sulphonate is a milder surfactant compared to lauryl sulfates and is used in high performing sulfate-free, shampoos, body wash, hand soap and pet care formulations.
Alpha Olefin Sulphonate is highly effective in unloading undesirable liquids and particulates from gas producing wells and exhibits exceptional thermal stability up to 400° F.


Alpha Olefin Sulphonate is readily biodegradable.
Alpha Olefin Sulphonate is used Sulfate-Free Shampoo All Purpose Cleaning Bar Soap Body Wash Facial Cleansers Hand Dishwashing Vehicle Wash Industrial Foaming Applications Commercial & Household Laundry Liquid Hand Soap.


Alpha Olefin Sulfonate is a mild anionic, high-foaming & well-emulsifying surfactant.
Alpha Olefin Sulphonate made primarily from coconut oils.
Alpha Olefin Sulphonate is stable at a wide pH range and can therefore be used in acidic environments.


Alpha Olefin Sulphonate has mild primary surfactant with excellent cleansing and degreasing properties (but non-drying on skin & mucous membranes).
Alpha Olefin Sulphonate has good wetting effect, foam booster, slight viscosity enhancer.
Alpha Olefin Sulphonate is easily compatible with other surfactants including non-ionic, amphoteric or anionic co-surfactants.


Alpha Olefin Sulphonate can be used for making sulfate-free cleansing products.
Alpha Olefin Sulphonate with linear alkenyl radicals from C12 to C18 are used as anionic surfactants in various areas of application due to their pronounced foam formation and foam stability (even with high water hardness), excellent fat-dissolving power and oil dissolving power as well as a favorable ecological profile and low aquatic toxicity and human toxicity.


Alpha Olefin Sulphonate is typically used in detergents and cleaning agents, for degreasing, in the emulsion polymerization, the conditioning of concrete and mortar as well as in the formulation of pesticides.
Alpha Olefin Sulphonate is being introduced in some shampoos as an alternative to sodium laureth sulfate.


When you use products that contain Alpha Olefin Sulphonate, these chemicals actually scoop out the contaminants in the hair follicles, which can be easily washed away with water.
Alpha Olefin Sulphonate is for dust control as well as shampoos, hand soaps and bath products, carpet foamer.


Alpha Olefin Sulphonate is used in various household and industrial applications such as concrete foamer.
When used in shampoos, Alpha Olefin Sulphonate is a surfactant that can emulsify dirt and oil on the hair and scalp.
Alpha Olefin Sulphonate is a pretty effective cleansing agent with good foaming properties.


Alpha Olefin Sulphonate is a 40%, an anionic biodegradable aqueous solution of sodium olefin (C-14 C-16) sulfonate, is an ideal surfactant for a variety of personal care and household and industrial applications.
Alpha Olefin Sulphonate is used for the care chemical industry.


-Alpha Olefin Sulphonate is used for cosmetic industry:
Alpha Olefin Sulphonate is a natural anionic surfactant.
Alpha Olefin Sulphonate is widely used in cosmetics industry.
Alpha Olefin Sulphonate is included in shampoos, liquid soaps, lotions, bath foams.
Alpha Olefin Sulphonate is also used in face and body care products, shower gels and other cosmetics.


-Skin care:
Alpha Olefin Sulphonate acts as a good cleansing agent.
Alpha Olefin Sulphonate mixes well with water and oil to remove the dust particles settled on the surface of the skin


-Hair care:
Alpha Olefin Sulphonate is an amazing surfactant and a foam forming agent.
Alpha Olefin Sulphonate helps the formulations act on the scalp and hair to leave it clean.
Further, Alpha Olefin Sulphonate helps in easy spreadability of the product throughout


-Skin care:
Alpha Olefin Sulphonate acts as a good cleansing agent.
Alpha Olefin Sulphonate mixes well with water and oil to remove the dust particles settled on the surface of the skin


-Application areas of Alpha Olefin Sulphonate:
*HI&I cleaning
*Emulsion polymerization
*Fire-fighting
*Personal care
*Laundry detergents
*Industrial auxiliaries
*Construction chemicals
*Oil fields
*Agriculture


-Suggestions for Use of Alpha Olefin Sulphonate:
Alpha Olefin Sulphonate is used Cold Process Soap, Body Wash Bases, Facial Cleansers, Liquid Hand Soap, Machine Dishwashing, Oil Dispersants (OD), Shampoos, Sulfate-Free, Suspension Concentrates (SC), Suspoemulsions (SE), Water Dispersible Granules (WG), Wettable Powders (WP).


-Hair care:
Alpha Olefin Sulphonate is an amazing surfactant and a foam forming agent.
Alpha Olefin Sulphonate helps the formulations act on the scalp and hair to leave it clean.
Further, Alpha Olefin Sulphonate helps in easy spreadability of the product throughout.



INDUSTRY USE OF ALPHA OLEFIN SULPHONATE:
Alpha olefin sulfonate’s primary use is in washing powder, liquid detergents, and soaps.
Other applications of Alpha Olefin Sulphonate include the textile, printing, and dyeing industries as well as the petrochemical industry.
Alpha olefin sulfonate is additionally used as an industrial foaming agent, wetting agent, concrete density improver, and pesticide emulsifier.



BENEFITS OF ALPHA OLEFIN SULPHONATE:
*Mild primary surfactant with excellent cleansing and degreasing properties (but non-drying on skin & mucous membranes)
*Good wetting effect, foam booster, slight viscosity enhancer
*Easily compatible with other surfactants including non-ionic, amphoteric or anionic co-surfactants
*Can be used for making sulfate-free cleansing products



FEATURES AND BENEFITS OF ALPHA OLEFIN SULPHONATE:
*Excellent solubility and compatibility with other surfactants, resulting in great formulating flexibility.
*Significant foaming, emulsifying, cleansing ability, and 100% biodegradability.
*Outstanding high-temperature stability, makes it the perfect surfactant for spray tower dried synthetic detergent.
*Outstanding hard water resistant property.
*Mild, low irritation to the skin.



CHARACTERISTICS OF ALPHA OLEFIN SULPHONATE:
Alpha Olefin Sulphonate has the following features:
*100% biodegradability
*Good wetting, foaming, detergency, emulsifying property
*Little skin irritant
*Good calcium soap dispersion and anti-hard water performances
*Dissolves in water and rinsed easily
*Good Stability, good compatibility with other kinds of surfactants



BENEFITS AND USES OF ALPHA OLEFIN SULPHONATE:
Alpha Olefin Sulphonate has an extraordinary ability to clean your skin without stripping it off its natural oils.
Add Alpha Olefin Sulphonate to your shampoos and conditioners to make some great sulfate-free products.
Alpha Olefin Sulphonate is skin and environmentally friendly.

When used in bubble baths Alpha Olefin Sulphonate produces a copious foam to give you a rich bathing and relaxing experience.
Alpha Olefin Sulphonate resists hard water well making it an efficient detergent and cleanser.
Alpha Olefin Sulphonate enhances the viscosity of your formulation and you can find it in almost all liquid detergents.



MANUFACTURING OF ALPHA OLEFIN SULPHONATE:
Alpha Olefin Sulphonate is a chemical compound composed of long-chain sulfonate salts made by the process of sulfonation of alpha-olefins.
Alpha Olefin Sulphonate is produced by oligomerization of ethylene, or by Fischer-Tropsch synthesis.
The process is followed by purification.



ADVANTAGES AND OUTLOOK OF ALPHA OLEFIN SULPHONATE:
Alpha Olefin Sulphonate has been used in personal care mainly as a primary or secondary surfactant in rinse-off products including hand washes, facial washes, bubble baths, shampoos and most commonly, body washes.
Concentrations exceeding 10% w/w in personal care formulations are considered acceptable, with Alpha Olefin Sulphonate use in shampoos and body washes generally at ~16% w/w as supplied and above.



ALPHA OLEFIN SULPHONATE PROPERTIES:
Commercially, Alpha Olefin Sulphonate is supplied as 30–40% w/w active solutions, which are clear to slightly yellow and whose viscosity generally ranges from 200–1000 cP.
The residual impurities found in Alpha Olefin Sulphonate may include unsulfonated matter, disulfonate, NaCl, NaSO4 and γ-, δ- and chlorosultones, all of which affect the material properties.

As noted, δ- and γ-sultones are known sensitizers with recommended levels not to exceed 34 ppm and 10 ppm, respectively.
Manufacturing processes using sodium hypochlorite as a bleaching agent may create additional unsaturated and chlorosultones as byproducts and potent skin sensitizers.

Residual unsulfonated matter, disulfonate and the salts NaCl and NaSO4 may affect the Krafft point.
Introductions of chain branching, unsaturation and polar segments into the Alpha Olefin Sulphonate structure also impact Krafft temperature, through influence of the surfactant unimer solubility.



PRODUCTION AND COMPOSITION OF ALPHA OLEFIN SULPHONATE:
Alpha Olefin Sulphonate is produced by sulfonation of alpha-olefins, typically using sulfur trioxide.
Subsequent alkaline hydrolysis gives a mixture of alkene sulfonates (60-65%) and hydroxyalkane sulfonates (35-40%).
The commercially available Alpha Olefin Sulphonate is mostly solutions with about 40% active ingredient content.



CHEMICAL PRODUCTION OF ALPHA OLEFIN SULPHONATE:
Alpha Olefin Sulphonate is available to buy due to its delicate but strong cleaning and detergent properties:
*As a constituent for detergents and cleaners, technical detergents and degreasers.
*Due to its alkalinity, Alpha Olefin Sulphonate is included in alkaline professional detergents.
*It is recommended to buy Alpha Olefin Sulphonate in the production of car shampoos
*Upholstery and carpet cleaners and other high foaming detergents.
*Also Alpha Olefin Sulphonate is used in the manufacture of polymer products.



WHAT DOES ALPHA OLEFIN SULPHONATE DO IN A FORMULATION?
*Cleansing
*Foaming
*Surfactant



REFINED OR UNREFINED?
Alpha Olefin Sulfonate (AOS) only exists as a refined product.



SAFETY PROFILE OF ALPHA OLEFIN SULPHONATE:
Alpha Olefin Sulphonate is safe to be used in rinse off products.
However, Alpha Olefin Sulphonate's concentration should not exceed 2% in leave on formulations.
Alpha Olefin Sulphonate can make the skin and hair dry, so it is not recommended for the dry skin types.
Further, Alpha Olefin Sulphonate can also be comedogenic and cause acne on highly sensitive skin.
Therefore, a patch test is beneficial prior to full usage.



PRODUCTION AND MANUFACTURE OF ALPHA OLEFIN SULPHONATE:
Olefins are mainly produced by polymerizing ethylene through different synthetic pathways such as the Oxo process, Shell Higher Olefin
Process (SHOP) or refinery cracking; however, the Ziegler process is more common.
The Oxo process produces a mixture of linear and branched α-olefin compositions, while Ziegler and SHOP products have lower levels of branching within their structure.



HOW TO USE ALPHA OLEFIN SULPHONATE:
*Melt the surfactants of choice.
*Add our Alpha Olefin Sulphonate to the melted surfactant base.
*Pour the base into the cold water phase and then add the oil phase to it.
*Stir and adjust the pH.



HOW ALPHA OLEFIN SULPHONATE WORKS?
Alpha Olefin Sulphonate works by breaking the surface tension of water which allows the water to clear dirt, dust, and grime.
Alpha Olefin Sulphonate forms micelles in water and works by attaching dirt to the hydrophobic end that gets washed away with water.



CONCENTRATION AND SOLUBILITY OFALPHA OLEFIN SULPHONATE:
The recommended concentration of Alpha Olefin Sulphonate is 3%-40% depending on the type of formulation.
Alpha Olefin Sulphonate is soluble in water and insoluble in oil.



WHAT DOES Alpha Olefin Sulphonate DO IN A FORMULATION?
*Cleansing
*Foaming
*Surfactant



PHYSICAL and CHEMICAL PROPERTIES of ALPHA OLEFIN SULPHONATE:
pH: 8.0-10.0
Solubility: Soluble in water
appearance at 20°C: yellowish to yellow liquid
density at 20°C, g/cm3, c.: 1.05
active matter, % wt.: 37 ± 1
pH, 10% aqueous solution: min. 11
Appearance: White or light yellow powder
Petroleum ether soluble(%): 5.0%Max
Sodium sulfate(%): 6.0%Max
free alkalinity(%): 1.0%Max
Water(%): 3.0Max
Ph value (1% aq.solution): 9.5-11.5
Whiteness (Wb): 80Min
Actives, %: 39
Boiling Point, ºC: one hundred
Cloud Point, °C: 7
CMC, mg/l: 301.0
Density at 25°C, g/ml: 1.06
Draves Wetting at 25°C, seconds: 15
Flash Point, °C: >94
Form at 25°C: liquid
Freeze Point, °C: -7
Pour Point, °C: -4

Upper Explosive Limit (%): Not available.
Surface Tension (dyn/cm or mN/m): Not Applicable
Lower Explosive Limit (%): Not available.
Volatile Component (%vol): Nil @ 38C
Vapour pressure (kPa): Negligible
Gas group: Not Available
Solubility in water: Miscible
pH as a solution (1%): 2 approx
Vapour density: (Air = 1) Not Applicable
VOC g/L: Not Available
pH: 8.0-10.0
Molecular Weight: 298.42 - 344.49
Solubility: Soluble in water
Molecular Weight: 298.42-344.49
Physical State: Solid
Appearance: white or light yellow powder
Physical state: Divided Solid
Relative density: (Water = 1) > 1
Odour: Not Available
Partition coefficient n-octanol / water: Not Available
Odour threshold: Not Available
Auto-ignition temperature: (°C) Not available.

Specific Gravity at 25°C: 1.06
Surface Tension, mN/m: 31.6
Viscosity at 25°C, cps: 125
Viscosity, cps: 79 (at 60°C)
RVOC, US EPA %: 0
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in: water, 100 mg/L @ 25 °C (est)
Density: 1.054g/cm3 at 20℃
vapor pressure: 0 Pa at 25℃
form: Powder
LogP: -1.3 at 20℃ and pH5.43
Surface tension: 36.1mN/m at 1g/L and 20℃
Dissociation constant: 0.15-0.38 at 25℃
Decomposition temperature: Not available.
Melting point / freezing point (°C): Not available.
Viscosity (cSt): Not Applicable
Initial boiling point and boiling range (°C): Not available.
Molecular weight (g/mol): Not Applicable
Flash point (°C): Not Available
Taste: Not Available
Evaporation rate: Non Volatile
Explosive properties: Not Available
Flammability: Not Available
Oxidising properties: Not Available



FIRST AID MEASURES of ALPHA OLEFIN SULPHONATE:
-Description of first aid measures:
*Eye Contact:
If this product comes in contact with the eyes:
Immediately hold eyelids apart and flush the eye continuously with running water and lower lids.
*Skin Contact:
If skin contact occurs:
Immediately remove all contaminated clothing, including footwear.
Flush skin and hair with running water (and soap if available).
*Inhalation:
Other measures are usually unnecessary.
*Ingestion:
Give water to rinse out mouth, then provide liquid slowly and as much as casualty can comfortably drink.
Seek medical advice.
-Indication of any immediate medical attention and special treatment needed:
Treat symptomatically.



ACCIDENTAL RELEASE MEASURES of ALPHA OLEFIN SULPHONATE:
-Methods and material for containment and cleaning up:
*Minor Spills:
Clean up all spills immediately.



FIRE FIGHTING MEASURES of ALPHA OLEFIN SULPHONATE:
-Extinguishing media:
Water spray or fog.
Foam.
Dry chemical powder.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ALPHA OLEFIN SULPHONATE:
-Exposure controls:
*Eye and face protection:
Safety glasses with side shields.
Chemical goggles.
*Hands/feet protection:
Care must be taken, when removing gloves and other protective equipment, to avoid all possible skin contact.
Contaminated leather items, such as shoes, belts and watch-bands should be removed.
Personal hygiene is a key element of effective hand care.



HANDLING and STORAGE of ALPHA OLEFIN SULPHONATE:
-Precautions for safe handling:
*Safe handling:
Use in a well-ventilated area.
Establish good housekeeping practices.
-Other information
Store in original containers.
Keep containers securely sealed.
Store in a cool, dry area protected from environmental extremes.
-Conditions for safe storage, including any incompatibilities:
*Suitable container:
Glass container is suitable for laboratory quantities
Polyethylene or polypropylene container.
Check all containers are clearly labelled and free from leaks.



STABILITY and REACTIVITY of ALPHA OLEFIN SULPHONATE:
-Chemical stability
Product is considered stable.
Hazardous polymerisation will not occur.



SYNONYMS:
Sodium alpha-olefin sulfonate
Sodium tetradecene sulfonate
Linear alpha-olefin
α-olefin sulfonate
Sodium a-olefin sulfonate
Sodium c14-16 olefin sulfonate
Sodium (2E)-2-Tetradecene-1-Sulfonate, 2-Tetradecene-1-Sulfonic Acid
Sodium alpha-olefin sulfonate
Sodium tetradecene sulfonate
Linear alpha-olefin
α-olefin sulfonate
Sodium a-olefin sulfonate
Sodium c14-16 olefin sulfonate
C14-C16-Alkanehydroxysulfonic acids sodium salts
Sulfonic acids C14-16-alkane hydroxy
C14-16-alkene, sodium salts
Α-alkenyl sulfonate (AOS)
C14-C16-Alkanehydroxysulfonic acids sodium salts
alpha-olefin
Bio-Terge AS-40K
α- olefin sulfonate
SODIUM A-OLEFIN SULFONATE
Alpha Olefin Sulfonate(AOS)
SODIUMC14-16OLEFINSULPHONATE
SODIUM C14-16 OLEFIN SULFONATE
SODIUM TETRADECENESULFONATE
SULFONIC ACIDS, C-16-16-ALKANE
SODIUM SALTS
SULFONIC ACIDS
C1416ALKANE HYDROXY
C1416ALKENE,SODIUM SALTS
SODIUM C14-16 OLEFIN SULFONATE
SODIUM TETRADECENESULFONATE
SULFONIC ACIDS C-16-16-ALKANE
SODIUM SALTS
SULFONIC ACIDS, C1416ALKANE HYDROXY
C1416ALKENE, SODIUM SALTS
NANSA LSS-92A
sulfonic acids, C14-16-alkane hydroxy and C14-16-alkene
alkenes, C14-16-alpha-, sulfonated, sodium salts
alpha-olefin sulphonic acid sodium salt
sodium olefin sulphonate
sodium C14-16-alpha-olefin sulfonate
Siponate A246L
Siponate 301-10F
alkyl olefin sulfonate
Alpha Olefin Sulfonate Powder
Sodium c14-16 Alpha Olefin Sulfonate
sodium c14-16 olefin sulfonate
C14-16 sodium alkenyl sulfonate


Alpha Olefin Sulfonate
MONOOLEIN; 1-(CIS-9-OCTADECENOYL)-RAC-GLYCEROL; 1-MONO[CIS-9-OCTADECENOYL]-RAC-GLYCEROL; 1-MONOLEIN; 1-MONOOLEIN; 1-MONOOLEOYL-RAC-GLYCEROL; 1-OLEOYL-RAC-GLYCEROL; 1-O-OLEYL-RAC-GLYCEROL; DELTA 9 CIS MONOOLEIN; DL-ALPHA-MONOOLEIN; GLYCEROL-1-MONOOLEATE; GLYCEROL ALPHA-MONOOLEATE; GLYCEROL MONOOLEATE; GLYCERYL CIS-9-OCTADECENOATE; GLYCERYL MONOOLEATE; MONOOLEIN; RAC-GLYCEROL 1-MONOOLEATE; 9-Octadecenoicacid(Z)-,monoesterwith1,2,3-propanetriol; adchemgmo; ajaxgmo; aldo40 CAS NO:25496-72-4
ALPHA TOCOPHEROL ACETATE
ALPHA TOCOPHEROL ACETATE Alpha Tocopherol acetate is a tocol. Alpha tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol stereoisomers. Moreover, RRR-alpha-tocopherol acetate is a relatively stabilized form of vitamin E that is most commonly used as a food additive when needed. Alpha tocopherol acetate is subsequently most commonly indicated for dietary supplementation in individuals who may demonstrate a genuine deficiency in vitamin E. Vitamin E itself is naturally found in various foods, added to others, or used in commercially available products as a dietary supplement. The recommended dietary allowances (RDAs) for vitamin E alpha-tocopherol are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months, males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg (10.4 IU) in ages 4-8 years, males = 11 mg (16.4 IU) females = 11 mg (16.4 IU) in ages 9-13 years, males = 15 mg (22.4 IU) females = 15 mg (22.4 IU) pregnancy = 15 mg (22.4 IU) lactation = 19 mg (28.4 IU) in ages 14+ years. Most individuals obtain adequate vitamin E intake from their diets; genuine vitamin E deficiency is considered to be rare. Nevertheless, vitamin E is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals. This biologic action of vitamin E consequently continues to generate ongoing interest and study in whether or not its antioxidant abilities may be used to help assist in preventing or treating a number of different conditions like cardiovascular disease, ocular conditions, diabetes, cancer and more. At the moment however, there exists a lack of formal data and evidence to support any such additional indications for vitamin E use. D-alpha tocopheryl acetate appears as odorless off-white crystals. Darkens at 401° F. Molecular Weight of Alpha Tocopherol acetate: 472.7 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) XLogP3-AA of Alpha Tocopherol acetate: 10.8 Computed by XLogP3 3.0 (PubChem release 2019.06.18) Hydrogen Bond Donor Count of Alpha Tocopherol acetate: 0 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Hydrogen Bond Acceptor Count of Alpha Tocopherol acetate: 3 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Rotatable Bond Count of Alpha Tocopherol acetate: 14 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Exact Mass of Alpha Tocopherol acetate: 472.391646 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Monoisotopic Mass of Alpha Tocopherol acetate: 472.391646 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Topological Polar Surface Area of Alpha Tocopherol acetate: 35.5 Ų Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Heavy Atom Count of Alpha Tocopherol acetate: 34 Computed by PubChem Formal Charge of Alpha Tocopherol acetate: 0 Computed by PubChem Complexity of Alpha Tocopherol acetate: 602 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Isotope Atom Count of Alpha Tocopherol acetate: 0 Computed by PubChem Defined Atom Stereocenter Count of Alpha Tocopherol acetate:3 Computed by PubChem Undefined Atom Stereocenter Count of Alpha Tocopherol acetate: 0 Computed by PubChem Defined Bond Stereocenter Count of Alpha Tocopherol acetate: 0 Computed by PubChem Undefined Bond Stereocenter Count of Alpha Tocopherol acetate: 0 Computed by PubChem Covalently-Bonded Unit Count of Alpha Tocopherol acetate: 1 Computed by PubChem Compound of Alpha Tocopherol acetate Is Canonicalized Yes Properties Related Categories Aloe Vera, Biochemicals and Reagents, Cell Biology, Linum usitatissimum (Flax), Lipids, Nutrition Research, Phytochemicals by Plant (Food/Spice/Herb), Prenols, Vitamin E, Vitamins Less... Quality Level 200 biological source synthetic (organic) assay ≥96% (HPLC) form viscous liquid application(s) HPLC: suitable color colorless to dark yellow density 0.96 g/mL at 20 °C (lit.) Show More (12) Description General description α-Tocopherol is a predominant form of vitamin E in human and animal tissues[1] and also in leaf chloroplasts.[3] It is the major form in supplements.[1] DL-α-Tocopherol acetate is considered as the only storage form of vitamin E.[2] Application DL-α-Tocopherol acetate has been used to study it effect on blood pressure and lipidic profile in streptozotocin-induced diabetes mellitus rats.[4] It has also been used as a standard in α-tocopherol analysis using plasma sample[5][6] and mature fresh tobacco leaves.[7] Packaging 5, 25, 100 g in glass bottle Biochem/physiol Actions Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Tocopherol acetate has properties similar but not identical to α-tocopherol. Tocopheryl acetate RRR-Alpha Tocopherol acetate RRR-Alpha Tocopherol acetate RRR-Alpha Tocopherol acetate Names IUPAC name [(2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-yl] acetate Other names α-Tocopherol acetate Vitamin E acetate Identifiers CAS Number 58-95-7 RRR-α-isomer check 3D model (JSmol) Interactive image ChEMBL ChEMBL1047 check ChemSpider 77987 check ECHA InfoCard 100.000.369 PubChem CID 86472 UNII A7E6112E4N check CompTox Dashboard (EPA) DTXSID1031096 InChI[show] SMILES[show] Properties Chemical formula C31H52O3 Molar mass 472.743 g/mol Appearance pale yellow, viscous liquid[1] Melting point –27.5 °C [1] Boiling point 240 °C decays without boiling[2] Solubility in water insoluble[1] Solubility soluble in acetone, chloroform, diethyl ether; poorly soluble in ethanol[1] Hazards NFPA 704 (fire diamond) NFPA 704 four-colored diamond 110 Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). check verify (what is check☒ ?) Infobox references Alpha Tocopherol acetate, also known as vitamin E acetate, is a synthetic form of vitamin E. It is the ester of acetic acid and α-tocopherol.[2] The U.S. Centers for Disease Control and Prevention says that vitamin E acetate is a very strong culprit of concern in the 2019 outbreak of vaping-associated pulmonary injury (VAPI),[3] but there is not yet sufficient evidence to rule out contributions from other chemicals.[4][5] Use in cosmetics Alpha Tocopherol acetate is often used in dermatological products such as skin creams. It is not oxidized and can penetrate through the skin to the living cells, where about 5% is converted to free tocopherol. Claims are made for beneficial antioxidant effects.[6] Alpha Tocopherol acetate is used as an alternative to tocopherol itself because the phenolic hydroxyl group is blocked, providing a less acidic product with a longer shelf life. It is believed that the acetate is slowly hydrolyzed after it is absorbed into the skin, regenerating tocopherol and providing protection against the sun's ultraviolet rays.[7] Tocopheryl acetate was first synthesized in 1963 by workers at Hoffmann-La Roche.[8] Although there is widespread use of tocopheryl acetate as a topical medication, with claims for improved wound healing and reduced scar tissue,[9] reviews have repeatedly concluded that there is insufficient evidence to support these claims.[10][11] There are reports of vitamin E-induced allergic contact dermatitis from use of vitamin E derivatives such as tocopheryl linoleate and tocopherol acetate in skin care products. Incidence is low despite widespread use.[12] Misuse Ingredient in vape liquids See also: 2019–20 vaping lung illness outbreak, Vaping-associated pulmonary injury, and Lacing (drugs) § Cannabis On September 5, 2019, the United States Food and Drug Administration (US FDA) announced that 10 out of 18, or 56% of the samples of vape liquids sent in by states, linked to recent vaping related lung disease outbreak in the United States, tested positive for vitamin E acetate[13] which had been used as a thickening agent by illicit THC vape cartridge manufacturers.[14] On November 8, 2019, the Centers for Disease Control and Prevention (CDC) identified vitamin E acetate as a very strong culprit of concern in the vaping-related illnesses, but has not ruled out other chemicals or toxicants as possible causes.[3] The CDC's findings were based on fluid samples from the lungs of 29 patients with vaping-associated pulmonary injury, which provided direct evidence of vitamin E acetate at the primary site of injury in all the 29 lung fluid samples tested.[3] Research suggests when vitamin E acetate is inhaled, it may interfere with normal lung functioning.[5] A 2020 study found that vaporizing vitamin E acetate produced carcinogenic alkenes and benzene, but also exceptionally toxic ketene gas, which may be a contributing factor to the pulmonary injuries.[15] Chemistry At room temperature, Alpha Tocopherol acetate is a fat-soluble liquid. It has 3 chiral centers and thus 8 stereoisomers. It is made by esterifying α-tocopherol with acetic acid. 2R,4R,8R-isomer, also known as RRR-Alpha Tocopherol acetate, is the most common isomer used for various purposes. This is because α-tocopherol occurs in the nature primarily as RRR-α-tocopherol.[2] α-Tocopherol acetate does not boil at atmospheric pressure and begins to degrade at 240 °C.[2] It can be vacuum distilled: it boils at 184 °C at 0.01 mmHg, at 194 °C (0.025 mmHg) and at 224 °C (0.3 mmHg). In practice, it is not degraded notably by air, visible light or UV-radiation. It has a refractive index of 1.4950–1.4972 at 20 °C.[1] α-Tocopherol acetate is hydrolyzed to α-tocopherol and acetic acid under suitable conditions or when ingested by people. What’s tocopheryl acetate? Alpha-tocopheryl acetate (ATA) is a specific form of vitamin E that’s often found in skin care products and dietary supplements. It’s also known as tocopheryl acetate, tocopherol acetate, or vitamin E acetate. Vitamin E is known for its antioxidant properties. Antioxidants help to protect your body from damaging compounds called free radicals. Normally, free radicals form when your body converts food into energy. However, free radicals can also come from UV light, cigarette smoke, and air pollution. In nature, vitamin E comes in the form of tocopheryl or tocotrienol. Both tocopheryl and tocotrienol have four forms, known as alpha, beta, gamma, and delta. Alpha-tocopheryl (AT) is the most active form of vitamin E in humans. Alpha Tocopherol acetateis more stable than AT, meaning it can better withstand environmental stresses such as heat, air, and light. This makes it ideal for use in supplements and fortified foods because it has a longer shelf life. Where can I find tocopheryl acetate? Cosmetics and supplements You’ll find Alpha Tocopherol acetatein a variety of skin care products. The antioxidant properties of vitamin E can help to prevent damage to skin caused by free radicals from UV exposure. Vitamin E may also have an anti-inflammatory effect on the skin. Due to its higher stability, Alpha Tocopherol acetateis also used in vitamin E dietary supplements. When taken orally, Alpha Tocopherol acetateis converted to AT within the intestine. Vitamin E is in most multi-vitamins, so be sure to check how much is in your multi-vitamin if you take one, before adding a supplement. Foods In addition to dietary supplements and cosmetic products, you can find vitamin E in the following foods: green leafy vegetables, such as broccoli and spinach oils, such as sunflower oil, wheat germ oil, and corn oil sunflower seeds nuts, such as almonds and peanuts whole grains fruits, such as kiwi and mango Vitamin E is also added to fortified foods, such as cereals, fruit juices, and many spreads. You can check food labels to see if vitamin E has been added. If you want to increase your vitamin E intake, you should start by first increasing your intake of these foods. Potential benefits Using AT on the skin, especially with vitamin C, helps to prevent UV damage to the skin. In a review of studies, the Linus Pauling Institute at Oregon State University found that using AT with vitamin C on the skin decreased sunburned cells, DNA damage, and skin pigmentation following UV exposure. However, AT is less stable in the environment than ATA, which makes it harder to store. While Alpha Tocopherol acetateis less sensitive to heat and light than AT is, there’s less conversion of Alpha Tocopherol acetateto the active AT form within the skin. This is because the cells in the upper layer of your skin are much less metabolically active. As a result, using cosmetic products containing Alpha Tocopherol acetateon your skin may not be very effective. This is supported by a study from 2011 published in the Medical Principles and Practice journal. Using several commercial skin care products, researchers looked at the conversion of Alpha Tocopherol acetateto the active AT form in the skin of live rats. They found that, while there was Alpha Tocopherol acetatein the upper levels of the skin after using the product, there was no active AT. While there are many studies on the potential benefits of AT, studies on the benefits of Alpha Tocopherol acetateare limited. The results of these studies on Alpha Tocopherol acetateare mixed. Alpha Tocopherol acetateusually needs to be used with other vitamins and minerals to have a beneficial effect. A 2013 study of over 4,000 participants with age-related macular degeneration (AMD) from the Age-Related Eye Disease Study found that their combination of high dose antioxidants C, E, and beta-carotene, along with zinc, worked to delay progression to advanced AMD. In another review of studies, the Linus Pauling Institute found that consuming Alpha Tocopherol acetatealong with other antioxidant supplements had no effect on either the development or prevention of cataracts. Regarding the benefits of vitamin E supplements overall, study results have been mixed on whether they’re beneficial for the following conditions: coronary heart disease cancer cognitive decline, such as Alzheimer’s disease Potential risks Most people don’t experience side effects when taking the recommended daily dose of vitamin E, which is 15 milligrams (mg). Too much Vitamin E can cause problems. The tolerable upper limit dose of vitamin E for adults is 1,000 mg. High doses above 1,000 mg have been associated with the following side effects: dizziness fatigue headaches weakness blurred vision abdominal pain diarrhea nausea If you take high doses of vitamin E supplements for over a year, your risk of bleeding may increase. Speak to your doctor before taking vitamin E supplements if you take anticoagulant medication. It’s unlikely that you’ll get too much vitamin E from foods, but it can happen if you’re also taking supplements. A 2011 studyTrusted Source published in the Journal of the American Medical Association also showed that men taking high doses of vitamin E supplements had a higher risk of developing prostate cancer. It’s important to remember that the FDA doesn’t monitor supplements for purity or quality, so choosing a reputable brand is essential. Using skin care products containing Alpha Tocopherol acetatecan also lead to an allergic reaction, skin reddening, or rash. The bottom line Alpha Tocopherol acetateis a form of vitamin E that’s often included in cosmetic products and dietary supplements due to its higher stability compared to AT. When taken orally, Alpha Tocopherol acetateis converted into active AT within the body. The effectiveness of Alpha Tocopherol acetatein cosmetic products seems to be limited because Alpha Tocopherol acetateisn’t effectively broken down to AT in the upper layers of skin. Additionally, research on the benefits of Alpha Tocopherol acetatesupplements is limited and the results are mixed at best. If you’re looking to get more vitamin E, try adding foods such as leafy green vegetables, nuts, and wheat germ oil to your diet. Speak with your doctor before adding any supplements.
Alpha-Methyl Styrene Dimer
alpha-Tocopherol; VITAMIN E; D-alpha-Tocopherol; 5,7,8-Trimethyltocol CAS NO : 59-02-9
ALPHA-TOCOPHEROL
Alpha-tocopherol is a class of vitamin E compounds naturally found in many different sources, such as oils, nuts, and vegetables.
Alpha-tocopherol is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.
Alpha-tocopherol supplements are available alone and in combination with other vitamins.
Alpha-tocopherol is also called vitamin E.


CAS-Number: 10191-41-0
EC-Number: 233-466-0
MDL number: MFCD00006848
Chemical formula: C29H50O2


Alpha-tocopherol is a fat-soluble vitamin with several forms, but alpha-tocopherol is the only one used by the human body.
Alpha-tocopherol is in a class of medications called antioxidants.
Alpha-tocopherol is the orally bioavailable alpha form of the naturally-occurring fat-soluble vitamin E, with potent antioxidant and cytoprotective activities.


Upon administration, Alpha-tocopherol neutralizes free radicals, thereby protecting tissues and organs from oxidative damage.
Alpha-tocopherol gets incorporated into biological membranes, prevents protein oxidation and inhibits lipid peroxidation, thereby maintaining cell membrane integrity and protecting the cell against damage.


In addition, Alpha-tocopherol inhibits the activity of protein kinase C (PKC) and PKC-mediated pathways.
Alpha-tocopherol also modulates the expression of various genes, plays a key role in neurological function, inhibits platelet aggregation and enhances vasodilation.
Compared with other forms of tocopherol, Alpha-tocopherol is the most biologically active form and is the form that is preferentially absorbed and retained in the body.


Alpha-tocopherol is a type of vitamin E.
Alpha-tocopherol's E number is "E307".
Alpha-tocopherol exists in eight different forms, four tocopherols and four tocotrienols.


All feature a chromane ring, with a hydroxyl group that can donate a hydrogen atom to reduce free radicals and a hydrophobic side chain which allows for penetration into biological membranes.
Alpha-tocopherol is compared to the others, α-tocopherol is preferentially absorbed and accumulated in humans.


Alpha-tocopherol is found in a variety of tissues, being lipid-soluble, and taken up by the body in a wide variety of ways.
The most prevalent form, Alpha-tocopherol, is involved in molecular, cellular, biochemical processes closely related to overall lipoprotein and lipid homeostasis.
Ongoing research is believed to be "critical for manipulation of Alpha-tocopherol homeostasis in a variety of oxidative stress-related disease conditions in humans.


One of these disease conditions is the Alpha-tocopherol role in the use by malaria parasites to protect themselves from the highly oxidative environment in erythrocytes.
Naturally occurring Alpha-tocopherol exists in eight chemical forms (alpha-, beta-, gamma-, and delta-tocopherol and alpha-, beta-, gamma-, and delta-tocotrienol) that have varying levels of biological activity.


Alpha-tocopherol is the only form that is recognized to meet human requirements.
Alpha-tocopherol (body’s main form of vitamin E) functions as an antioxidant, regulates cell signaling, influences immune function and inhibits coagulation.
Alpha-tocopherol is a fat soluble vitamin and potent antioxidant that is believed to be important in protecting cells from oxidative stress, regulating immune function, maintaining endothelial cell integrity and balancing normal coagulation.


Alpha-tocopherol is a fat-soluble vitamin that has antioxidant properties.
Alpha-tocopherol functions as a chain-breaking antioxidant that prevents the propagation of lipid per-oxidation.
Alpha-tocopherol and CoQ10 are the primary fat-soluble antioxidants in cell membranes and lipoproteins.


Alpha-tocopherol protects polyunsaturated fatty acids (PUFAs) within membrane phospholipids and in plasma lipoproteins.
Alpha-tocopherol is transported in plasma in lipoproteins and serves as the most important membrane protective antioxidant and free radical scavenger in the body.
Serum concentrations of Alpha-tocopherol depend on the liver, which takes up the nutrient after the various forms are absorbed from the small intestine.


Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements.
In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol stereoisomers.


Moreover, RRR-alpha-tocopherol acetate is a relatively stabilized form of vitamin E that is most commonly used as a food additive when needed 2.
Alpha-tocopherol, also known as vitamin E1, is one of several forms of vitamin E.
Alpha-tocopherol appears as a light yellow, viscous, odorless, oily liquid that deteriorates on exposure to light.


Alpha-tocopherol is obtained from wheat germ oil or by synthesis, biologically exhibits the most vitamin E activity of the α-tocopherols, and is an antioxidant retarding rancidity by interfering with the autoxidation of fats.
Alpha-tocopherol is found in foods such as vegetable oils and shortening, meat, eggs, milk, and leafy vegetables.


Alpha-tocopherol is important for many processes in the body.
Alpha-tocopherol consists of a d (d-alpha tocopherol) isomer that is more active than a mixture of d and l (dl-Alpha Tocopherol) isomers.
Alpha-tocopherol has many important roles in the body.


Not only does Alpha-tocopherol participate in making red blood cells that carry oxygen throughout the body, but it also contributes to maintaining optimal immune function.
Moreover, Alpha-tocopherol is needed to keep blood from clotting within blood vessels but its main role is to act as an antioxidant in the body, meaning it protects cells against oxidative damage.


Alpha-tocopherol, therefore, protects our body from oxidative stress and may help prevent and treat the symptoms of chronic inflammatory conditions such as diabetes and osteoarthritis.
Alpha-tocopherol is a lipid-soluble form of Vitamin E important to human health as an antioxidant.


Often the result of poor nutrition or low absorption of dietary fat, vitamin E deficiency is monitored in patient serum samples by LC-MS/MS or HPLC.
Alpha-tocopherol predominates in the body due to specific mechanisms which favour its accumulation.
For example, in the liver ‘α-tocopherol transfer protein’ preferentially incorporates α-tocopherol into plasma lipoproteins.


The mechanisms are not yet fully understood, nevertheless, because of this, Alpha-tocopherol has traditionally been considered the best form of vitamin E to supplement.
Alpha-tocopherol has potent antioxidant capabilities and acts specifically (along with the other tocopherols and tocotrienols) as a fat-soluble antioxidant and is involved in reducing lipid peroxidation and supporting membrane stability.



USES and APPLICATIONS of ALPHA-TOCOPHEROL:
Alpha-tocopherol is used as a dietary supplement when the amount of vitamin E taken in the diet is not enough.
Alpha-tocopherol is also used to treat vitamin E deficiency in those at risk due to certain diseases and conditions.
Alpha-tocopherol is needed by the body to support the immune system and for blood clotting.


Alpha-tocopherol works as an antioxidant to protect your cells against free radicals.
Alpha-tocopherol boosts the immune system and helps keep blood clots from forming.
Alpha-tocopherol also helps prevent cell damage caused by free radicals (highly reactive chemicals).


Alpha-tocopherol is being studied in the prevention and treatment of some types of cancer.
Alpha-tocopherol is a type of antioxidant.
Alpha-tocopherol's main role is to act as an antioxidant, scavenging loose electrons—so-called “free radicals”—that can damage cells.


Alpha-tocopherol also enhances immune function and prevents clots from forming in heart arteries.
Antioxidant vitamins, including vitamin E, came to public attention in the 1980s when scientists began to understand that free radical damage was involved in the early stages of artery-clogging atherosclerosis, and might also contribute to cancer, vision loss, and a host of other chronic conditions.


Vitamin E has the ability to protect cells from free radical damage as well as reduce the production of free radicals in certain situations.
Alpha-tocopherol is used by many in fighting auto-immue diseases and some infections.
Alpha-tocopherol can be found in the following food sources: soya; corn and olive oil; nuts; seeds; and wheat germ.


Natural Alpha-tocopherol includes four tocopherols, called alpha, beta, gamma and delta tocopherol respectively.
The form used in the human body is Alpha-tocopherol, and this form is necessary to treat vitamin E deficiency.
Only this form is bound by the liver transport protein called Alpha-tocopherol transport protein, which carries it to the site where it is incorporated into lipoproteins and carried to other parts of the body.


Nevertheless, Alpha-tocopherol is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals.
This biologic action of Alpha-tocopherol consequently continues to generate ongoing interest and study in whether or not its antioxidant abilities may be used to help assist in preventing or treating a number of different conditions like cardiovascular disease, ocular conditions, diabetes, cancer and more.


The body will primarily use Alpha-tocopherol and once it has exerted its effects as an antioxidant it is converted to a tocopheryl radical and therefore becomes pro-oxidative itself.
The tocopheryl radical then needs to be regenerated back into Alpha-tocopherol, by either vitamin C, glutathione or CoQ10, so that it can once again act as an antioxidant.


Alpha-tocopherol is used to treat Vitamin E deficiency.
Alpha-tocopherol is available as a liquid and as liquid-filled capsules.
Alpha-tocopherol, also known as vitamin E (commonly found on the market as vitamin E Alpha Tocopherol 400 IU), this is one of the essential vitamins for the body.


Alpha-tocopherol helps maintain optimal immune function and optimal blood viscosity, both important factors in an athletes’ ability to train and compete.
Alpha-tocopherol is also said to help ease muscle cramps.
Athletes have higher needs in Alpha-tocopherol than sedentary people.


In conclusion, Alpha-tocopherol levels impact many aspects of our mental and physical health.
In order to make sure that your Alpha-tocopherol levels are balanced and steady, make sure to test your levels and to evaluate how you can make the right changes to rebalance your body and mind.


-Other uses for this medicine
Alpha-tocopherol is used along with other vitamins and minerals to reduce the risk of age-related macular degeneration (AMD; an ongoing disease of the eye that causes loss of the ability to see straight ahead and may make it more difficult to read, drive, or perform other daily activities) in certain people.


-Food & Nutrition:
Oils & Fats, Confectionery & Bakery, Snacks & Cereals, Cocoa & Chocolate, Spices & Condiments, Sauces & Dressings, Meat Products, Baby Food, Soft Capsules, Dietetic Products, Nutraceutical Formulations, Food Supplements, etc.


-Cosmetics & Personal Care:
Anti-Aging Care, Anti-Wrinkle Care, Daily Care, Skin Protection, Sun & After-sun Care, Hair Care, Hand & Nail Care, Men Care, etc.
-Animal Nutrition:
Pet Food, Feed, Cereals, etc.


-Uses of the drug Alpha Tocopherol:
Alpha-tocopherol drug is used in the treatment and prevention of vitamin E deficiency.
On the other hand, the drug is contraindicated in cases of hypersensitivity to Alpha-tocopherol or to other components of the drug.



BENEFITS OF ALPHA-TOCOPHEROL:
*Higher bioavailability than Synthetic Vitamin E
*Protects cell membranes and strengthens the immune system
*Reduces the risk of certain diseases
*Possibility of declaring “Source of Vitamin E” in packaging
*Fights oxidative stress by blocking free radicals
*Increases skin hydration and prevents appearance of wrinkles
*It has anti-inflammatory and healing properties
*Acts as natural barrier against UV rays and toxins
*Promotes hair growth and improves hair’s appearance
*Protects the animal during the gestation period
*Prevents the loss of nutritional value of fatty acids



STEREOISOMERS OF ALPHA-TOCOPHEROL:
Alpha-tocopherol has three stereocenters, so it is a chiral molecule.
The eight stereoisomers of α-tocopherol differ in the configuration of these stereocenters.
RRR-α-tocopherol is the natural one.

The older name of RRR-α-tocopherol is d-α-tocopherol, but this d/l naming should no longer be used, because whether l-α-tocopherol should mean SSS enantiomer or the SRR diastereomer is not clear, from historical reasons.
The SRR may be named 2-epi-α-tocopherol, the diastereomeric mixture of RRR-α-tocopherol and 2-epi-α-tocopherol may be called 2-ambo-α-tocopherol (formerly named dl-α-tocopherol). The mixture of all eight diastereomers is called all-rac-α-tocopherol.

One IU of tocopherol is defined as 2⁄3 milligram of RRR-α-tocopherol (formerly named d-α-tocopherol).
IU is also defined as 0.9 mg of an equal mix of the eight stereoisomers, which is a racemic mixture, all-rac-α-tocopheryl acetate.
This mix of stereoisomers is often called dl-α-tocopheryl acetate.
Starting with May 2016, the IU unit is made obsolete, such that 1 mg of "Vitamin E" is 1 mg of d-alpha-tocopherol or 2 mg of dl-alpha-tocopherol.



ALPHA-TOCOPHEROL'S MECHANISM OF ACTION:
Vitamin E is a general term for natural and synthetic compounds with the most important group of substances being tocopherol drugs, in which Alpha Tocopherol with the strongest activity is mainly used in treatment.
In addition, other classes of tocopherol drugs including beta, gamma and delta tocopherol are not used in treatment.

Alpha-tocopherol is a fat-soluble vitamin, widely distributed in food, especially vegetable oils, especially wheat germ oil, sunflower oil, cottonseed oil, cereals and eggs.
However, Alpha-tocopherol will be lost during storage and cooking.

The daily requirement for Alpha-tocopherol is about 4 - 15 mg. Alpha Tocopherol deficiency is rare, occurring only in people who are unable to absorb vitamin E or have an inherited disease that prevents normal blood levels of vitamin E from being maintained.
The exact biological function of Alpha-tocopherol is not fully known, but it is considered an antioxidant, preventing the oxidation of polyunsaturated fatty acids (this is a component of cell membranes), phospholipids and plasma lipoproteins), when free radicals are generated, they have the ability to damage cell membranes, proteins, and nucleic acids, leading to cell dysfunction and disease.

Alpha-tocopherol reacts with free radicals to lose peroxyl radicals but not to generate more free radicals.
Due to the antioxidant properties of Alpha-tocopherol, there have been many studies using vitamin E to alleviate symptoms of dementia in Alzheimer's disease, age-related macular degeneration, cancer, sclerosis Arteriosclerosis, coronary artery, cataract.



HOW SHOULD ALPHA-TOCOPHEROL BE USED?
Alpha-tocopherol comes as a capsule, gel capsule, and liquid drops to take by mouth.
Alpha-tocopherol is usually taken once a day or as directed by your doctor.
Alpha-tocopherol is available without a prescription, but your doctor may prescribe it to treat certain conditions.

Follow the directions on the package or on your product label or doctor's instructions carefully, and ask your doctor or pharmacist to explain any part you do not understand.
Take Alpha-tocopherol exactly as directed.
Do not take more or less of it or take it more often than recommended by your doctor.



PHYSICAL and CHEMICAL PROPERTIES of ALPHA-TOCOPHEROL:
Chemical formula: C29H50O2
Molar mass: 430.71 g/mol
Appearance: yellow-brown viscous liquid
Density: 0.950 g/cm3
Melting point: 2.5 to 3.5 °C (36.5 to 38.3 °F; 275.6 to 276.6 K)
Boiling point: 200 to 220 °C (392 to 428 °F; 473 to 493 K) at 0.1 mmHg
Solubility in water: insoluble
Solubility: soluble in alcohol, ether, acetone, oils
Boiling point: 393 °C (1013 hPa)
Density: 0.95 g/cm3 (20 °C)
Ignition temperature: 280 °C
Melting Point: 2.5 - 3.5 °C
Vapor pressure: Solubility: Appearance: clear, colourless to yellow-brownish, viscous, oily liquid; almost odourless
Acidity conforms:
Optical rotation: α 20/D (100 g/l; anhydrous ethanol) -0.01 - 0.01 °
Optical rotation: α 25/D (100 g/l; chloroforme) -0.05 - 0.05 °
Refractive index: (n 20/D) 1.503 - 1.507
Specific absorptivity: A 1%/1cm (292 nm; 0,1 g/l, anhydrous ethanol) 72 - 76
Specific absorptivity: A 1%/1cm (292 nm; 0,05 g/l , anhydrous Ethanol) 71 - 76
Heavy metals (as Pb): ≤ 10 ppm

Molecular Weight: 430.7
XLogP3-AA: 10.7
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 12
Exact Mass: 430.381080833
Monoisotopic Mass: 430.381080833
Topological Polar Surface Area: 29.5 Ų
Heavy Atom Count: 31
Formal Charge: 0
Complexity: 503
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 3
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Physical state: viscous
Color: light yellow
Odor: odorless
Melting point/freezing point:
Melting point: 2,5 - 3,5 °C
Initial boiling point and boiling range: 208 - 210 °C at 0,0266 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: > 300 °C
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 4.200 mPa.s at 20 °C
Water solubility: 0,00001 g/l
Partition coefficient: n-octanol/water: log Pow: > 6
Vapor pressure: 13 hPa at 155 °C
Density: 0,95 g/mL at 20 °C
Relative density: 0,95 at 25 °C
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available



FIRST AID MEASURES of ALPHA-TOCOPHEROL:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ALPHA-TOCOPHEROL:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ALPHA-TOCOPHEROL:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ALPHA-TOCOPHEROL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.Safety glasses
*Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ALPHA-TOCOPHEROL:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
*Storage stability:
Recommended storage temperature: 2 - 8 °C



STABILITY and REACTIVITY of ALPHA-TOCOPHEROL:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Incompatible materials:
No data available



SYNONYMS:
(2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-ol
VITAMIN E
alpha-Tocopherol
D-alpha-Tocopherol
59-02-9
(+)-alpha-Tocopherol
5,7,8-Trimethyltocol
Aquasol E
TOCOPHEROL
2074-53-5
(R,R,R)-alpha-Tocopherol
Phytogermine
Eprolin
a-Tocopherol
(2R,4'R,8'R)-alpha-Tocopherol
dl-a-Tocopherol
Denamone
Viteolin
Esorb
alpha-Tocopherol, D-
Tocopherol alpha
alpha-Vitamin E
alpha Tocopherol
D-alpha tocopherol
(2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL
(R)-2,5,7,8-Tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-ol
Vitamin Ea
1406-18-4
Syntopherol
Tocopherol (R,S)
CHEBI:18145
Vitamin-E
Evitaminum
Profecundin
Waynecomycin
Almefrol
Emipherol
Epsilan
Etamican
Tokopharm
Vascuals
Vitayonon
Etavit
Ilitia
Evion
(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-ol
BPBio1_000362
18920-62-2
Vitaplex E
Eprolin S
Spavit E
ido-E
Endo E
N9PR3490H9
Vita E
Lan-E
Med-E
Antisterility vitamin
a-Vitamin E
(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2R)-
Vi-E
E307
(+/-)-alpha-Tocopherol
2,5,7,8-Tetramethyl-2-(4',8',12'-trimethyltridecyl)-6-chromanol
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2R)-rel-
Viprimol
alpha-Tokoferol
d-a-tocopherol
MFCD00072045
rel-alpha-Vitamin E
RRR-alpha-tocopherol
Vitamin E alpha
Viterra E
E Prolin
CAS-59-02-9
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, (2R)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, (2R-(2R*(4R*,8R*)))-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, [2R-[2R*(4R*,8R*)]]-
SMR000471844
VIV
alpha-Tocopherol acid
Tenox GT 1
Rhenogran Ronotec 50
Covitol F 1000
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol
E 307 (tocopherol)
(all-R)-alpha-Tocopherol
Phytogermin
Palmvtee
alpha-Tocoferol
(+-)-Med-E
UNII-N9PR3490H9
Vitamin Ealpha
CCRIS 3588
NSC-20812
a-D-Tocopherol
.ALPHA.-TOCOPHEROL, D-
HSDB 2556
Pheryl-E
Vita plus E
d-..-Tocopherol
Vitamin e d-alpha
NCGC00016688-02
(+)--tocopherol
Prestwick_653
EINECS 200-412-2
EINECS 215-798-8
EINECS 218-197-9
.alpha.-Vitamin E
(+)-a-Tocopherol
NSC 20812
NSC 82623
RRR-alpha-tocopheryl
Vitamin E [USP]
()-alpha-Tocopherol
delta-alpha-tocopherol
alpha-delta-Tocopherol
Tocopherol, d-alpha-
Vitamin E (D-form)
CHEMBL47
(R,R,R)-a-Tocopherol
Prestwick3_000404
E 307
(+)- alpha -Tocopherol
(+)-.alpha.-Tocopherol
bmse000600
R,r,r-.alpha.-tocopherol
EC 200-412-2
SCHEMBL3097
UNII-H4N855PNZ1
BIDD:PXR0174
BSPBio_000328
MLS001066396
MLS001335981
MLS001335982
BIDD:ER0562
INS NO.307A
T1539_SIGMA
H4N855PNZ1
INS-307A
(+)-ALPHA-TOCOPHEROL-
ALPHA-TOCOPHEROL [HSDB]
DTXSID0026339
(2R,4'R,8'R)-a-Tocopherol
.ALPHA.-TOCOPHEROL [MI]
HMS2096A10
HMS2231G08
C29H50O2 (D-alpha-tocopherol)
D-ALPHA TOCOPHEROL [MART.]
HY-N0683
ZINC4095858
Tox21_110563
Tox21_113208
Tox21_202081
BDBM50458513
E-307A
LMPR02020001
AKOS004910417
CS-8161
DB00163
(2R)-2-((4R,8R)-4,8,12-trimethyltridecyl)-2,5,7,8-tetramethylchroman-6-ol
NCGC00142625-01
NCGC00142625-04
NCGC00142625-05
NCGC00142625-06
NCGC00142625-07
NCGC00142625-10
NCGC00259630-01
(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-ol
(2R*(4R*,8R*))-(1)-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol
AS-13990
J24.260H
T2309
C02477
d-alpha, d-beta, d-gamma & d-delta tocopherols
EN300-7417123
Q158348
Q-201932
W-107596
W-109164
Z2235811339
07AA93F0-3339-4EEC-B50B-ADB70F657087
(2R,4'R,8'R)-2,5,7,8-Tetramethyl-2-(4',8',12'-trimethyltridecyl)-6-chromanol
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1- -benzopyran-6-ol
(2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol
(R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-ol
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, 2R- 2R*(4R*,8R*) -
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, (2R*(4R*,8R*))-(+-)-
Vitamin E
DL-all-rac-α-Tocopherol
(±)-α-Tocopherol


ALPHA-TOCOPHEROL (VITAMIN E)
Alpha-tocopherol (Vitamin E) is an alpha-tocopherol that has R,R,R configuration.
The naturally occurring stereoisomer of alpha-tocopherol, Alpha-tocopherol (Vitamin E) is found particularly in sunflower and olive oils.
Alpha-tocopherol (Vitamin E) has a role as an antioxidant, a nutraceutical, an antiatherogenic agent, an EC 2.7.11.13 (protein kinase C) inhibitor, an anticoagulant, an immunomodulator, an antiviral agent, a micronutrient, an algal metabolite and a plant metabolite.

CAS: 2074-53-5
MF: C29H50O2
MW: 430.71
EINECS: 218-197-9

Alpha-tocopherol (Vitamin E) is an enantiomer of a (S,S,S)-alpha-tocopherol.
Alpha-tocopherol (Vitamin E)is a fat-soluble vitamin with several forms, but alpha-tocopherol is the only one used by the human body.
Alpha-tocopherol (Vitamin E)'s main role is to act as an antioxidant, scavenging loose electrons—so-called “free radicals”—that can damage cells.
Alpha-tocopherol (Vitamin E) also enhances immune function and prevents clots from forming in heart arteries.
Antioxidant vitamins, including Alpha-tocopherol (Vitamin E), came to public attention in the 1980s when scientists began to understand that free radical damage was involved in the early stages of artery-clogging atherosclerosis, and might also contribute to cancer, vision loss, and a host of other chronic conditions.
Alpha-tocopherol (Vitamin E) has the ability to protect cells from free radical damage as well as reduce the production of free radicals in certain situations.
However, conflicting study results have dimmed some of the promise of using high dose vitamin E to prevent chronic diseases.

Alpha-tocopherol (Vitamin E) is a group of eight fat soluble compounds that include four tocopherols and four tocotrienols.
Alpha-tocopherol (Vitamin E) deficiency, which is rare and usually due to an underlying problem with digesting dietary fat rather than from a diet low in vitamin E, can cause nerve problems.
Alpha-tocopherol (Vitamin E) is a fat-soluble antioxidant which may help protect cell membranes from reactive oxygen species.
Worldwide, government organizations recommend adults consume in the range of 3 to 15 mg per day.
As of 2016, consumption was below recommendations according to a worldwide summary of more than one hundred studies that reported a median dietary intake of 6.2 mg per day for alpha-tocopherol.

Population studies suggested that people who consumed foods with more Alpha-tocopherol (Vitamin E), or who chose on their own to consume a vitamin E dietary supplement, had lower incidence of cardiovascular diseases, cancer, dementia, and other diseases.
However, placebo-controlled clinical trials using Alpha-tocopherol (Vitamin E) as a supplement, with daily amounts as high as 2,000 mg per day, could not always replicate these findings.
In the United States Alpha-tocopherol (Vitamin E) supplement use peaked around 2002, but has declined by more than half by 2006.
The authors theorized that declining use may have been due to publications of large placebo-controlled studies that showed either no benefits or actual negative consequences from high-dose Alpha-tocopherol (Vitamin E).

Both natural and synthetic tocopherols are subject to oxidation, so dietary supplements are esterified, creating tocopheryl acetate for stability purposes.
Tocopherols and tocotrienols both occur in α (alpha), β (beta), γ (gamma), and δ (delta) forms, as determined by the number and position of methyl groups on the chromanol ring.
All eight of these vitamers feature a chromane double ring, with a hydroxyl group that can donate a hydrogen atom to reduce free radicals, and a hydrophobic side chain that allows for penetration into biological membranes.

Alpha-tocopherol (Vitamin E) was discovered in 1922, isolated in 1935, and first synthesized in 1938.
Because the vitamin activity was first identified as essential for fertilized eggs to result in live births (in rats), it was given the name "tocopherol" from Greek words meaning birth and to bear or carry.
Alpha-tocopherol (Vitamin E), either naturally extracted from plant oils or, most commonly, as the synthetic tocopheryl acetate, is sold as a popular dietary supplement, either by itself or incorporated into a multivitamin product, and in oils or lotions for use on skin.

Alpha-tocopherol (Vitamin E) Chemical Properties
Boiling point: 485.9±0.0 °C(Predicted)
Density: 0.93
Storage temp.: Store at -20°C,protect from light
Solubility Ethanol: 50 mg/mL (116.09 mM); DMSO: 16.11 mg/mL (37.40 mM)
pka: 11.40±0.40(Predicted)
CAS DataBase Reference: 2074-53-5

Physical properties
Alpha-tocopherol (Vitamin E) has demonstrated some success in the treatment of yellow nail syndrome when taken orally (600 EU to 1200 EU daily) for several months.
Topically-applied Alpha-tocopherol (Vitamin E) has also shown significant improvement in symptoms of yellow nail syndrome, as well as increased nail growth rates after six months.

Chemistry
The nutritional content of Alpha-tocopherol (Vitamin E) is defined by equivalency to 100% RRR-configuration α-tocopherol activity.
The molecules that contribute α-tocopherol activity are four tocopherols and four tocotrienols, within each group of four identified by the prefixes alpha- (α-), beta- (β-), gamma- (γ-), and delta- (δ-).
For alpha(α)-tocopherol each of the three "R" sites has a methyl group (CH3) attached.
For beta(β)-tocopherol: R1 = methyl group, R2 = H, R3 = methyl group.
For gamma(γ)-tocopherol: R1 = H, R2 = methyl group, R3 = methyl group. For delta(δ)-tocopherol: R1 = H, R2 = H, R3 = methyl group.
The same configurations exist for the tocotrienols, except that the hydrophobic side chain has three carbon-carbon double bonds whereas the tocopherols have a saturated side chain.

Uses
Alpha-tocopherol (Vitamin E) is considered the most important oil-soluble anti-oxidant and freeradical scavenger.
Studies indicate that Alpha-tocopherol (Vitamin E) performs these functions when topically applied.
Alpha-tocopherol (Vitamin E) is also a photoprotectant, and it helps protect the cellular membrane from free-radical damage.
In addition, Alpha-tocopherol (Vitamin E) serves a preservative function given its ability to protect against oxidation.
This benefits not only the skin, but also the product in terms of longevity.

As a moisturizer, vitamin e is well-absorbed through the skin, demonstrating a strong affinity with small blood vessels and an ability to enhance blood circulation in the skin.
Alpha-tocopherol (Vitamin E) is also thought to improve the skin’s water-binding ability.
In addition, Alpha-tocopherol (Vitamin E) emulsions have been found to reduce transepidermal water loss, thereby improving the appearance of rough, dry, and damaged skin.
Alpha-tocopherol (Vitamin E) is also believed to help maintain the connective tissue.
There is evidence that vitamin e is effective in preventing irritation owing to sun exposure: studies show that Alpha-tocopherol (Vitamin E) topically applied prior to uV irradiation is protective against epidermal cell damage caused by inflammation.
This indicates possible anti-inflammatory properties.

Lipid peroxidation in tissues may be one cause of skin aging.
Vitamin e, however, appears to counteract decreased functioning of the sebaceous glands and to reduce excessive skin pigmentation, which is found to increase almost linearly with age.
Alpha-tocopherol (Vitamin E) is available also as a tocopherol-polypeptide complex that delivers the vitamin in a waterdispersable form.
In this way, when incorporated into cosmetic formulations, Alpha-tocopherol (Vitamin E) does not need other compounds to assist in its solubilization.
Alpha-tocopherol (Vitamin E) is useful in anti-aging creams and lotions, and in uV protective products, tocopherol is a naturally occurring vitamin e found in a variety of cereal germ oils including wheat germ oil.
Alpha-tocopherol (Vitamin E) can also be produced synthetically.

Clinical Use
Deficiency of Alpha-tocopherol (Vitamin E) is characterized by low serum tocopherol levels and a positive hydrogen peroxide hemolysis test.
This deficiency is believed to occur in patients with biliary, pancreatic, or intestinal disease that is characterized by excessive steatorrhea.
Premature infants with a high intake of fatty acids exhibit a deficiency syndrome characterized by edema, anemia, and low tocopherol levels.
This condition is reversed by giving Alpha-tocopherol (Vitamin E).

benefits
Alpha-tocopherol (Vitamin E) is a fat-soluble nutrient found in many foods.
Alpha-tocopherol (Vitamin E) is the most abundant antioxidant in the skin and the most important lipid-soluble, membrane-bound antioxidant in the body.
The body also needs Alpha-tocopherol (Vitamin E) to boost its immune system so that it can fight off invading bacteria and viruses.
Alpha-tocopherol (Vitamin E) helps to widen blood vessels and keep blood from clotting within them.
In addition, cells use Alpha-tocopherol (Vitamin E) to interact with each other and to carry out many important functions.

Indications
Alpha-tocopherol (Vitamin E) is a potent antioxidant that is capable of protecting polyunsaturated fatty acids from oxidative breakdown.
This vitamin also functions to enhance vitamin A use.
Although several other physiological actions have been suggested, to date no unifying concept exists to explain these actions.
Alpha-tocopherol (Vitamin E) is found in a variety of foodstuffs, the richest sources being plant oils, including wheat germ and rice, and the lipids of green leaves.

Side effects
Prolonged administration of large dosages of Alpha-tocopherol (Vitamin E) may result in muscle weakness, fatigue, headache, and nausea.
This toxicity can be reversed by discontinuing the large-dose supplementation.

Toxicology
Alpha-tocopherol (Vitamin E) is known as vitamin E and exists in many kind of plants, especially in lettuce and alfalfa.
Alpha-tocopherol (Vitamin E)'s color changes from yellow to dark brown when exposed to sunlight.
Natural vegetable oils are not readily oxidized due to the presence of tocopherol.
During refining processes, however, tocopherol may be removed from oils; consequently, refined vegetable oils can become unstable toward oxidation.
In one experiment, Alpha-tocopherol (Vitamin E) appeared to be relatively innocuous, having been given to patients for months both orally and parenterally at a dosage level of 300 mg/day without any observed ill effects.
However, in another experiment, 6 out of 13 patients given similar doses complained of headache, nausea, fatigue, dizziness, and blurred vision.
Although the chronic toxicity of Alpha-tocopherol (Vitamin E) has not been thoroughly studied, WHO recommends 2 mg/kg/day as the maximum daily dose.

Synonyms
VITAMIN E
alpha-Tocopherol
D-alpha-Tocopherol
59-02-9
5,7,8-Trimethyltocol
(+)-alpha-Tocopherol
alpha Tocopherol
Phytogermine
TOCOPHEROL
2074-53-5
(R,R,R)-alpha-Tocopherol
Syntopherol
Viteolin
Eprolin
Esorb
a-Tocopherol
(2R,4'R,8'R)-alpha-Tocopherol
Tocopherol alpha
dl-a-Tocopherol
Profecundin
Denamone
Epsilan
Tokopharm
Vascuals
Viprimol
Etavit
alpha-Tokoferol
Evion
alpha-Tocopherol, D-
d-a-tocopherol
alpha-Vitamin E
Vitamin E alpha
Eprolin S
Viterra E
E Prolin
D-alpha tocopherol
Aquasol E
Lan-E
Med-E
Antisterility vitamin
alpha-Tocopherol acid
Tenox GT 1
Vi-E
Rhenogran Ronotec 50
(2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL
Covitol F 1000
Waynecomycin
E 307 (tocopherol)
(R)-2,5,7,8-Tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-ol
Vitamin Ea
a-D-Tocopherol
ido-E
Tocopherol (R,S)
(+)-a-Tocopherol
CCRIS 3588
1406-18-4
CHEBI:18145
Vitamin-E
2,5,7,8-Tetramethyl-2-(4',8',12'-trimethyltridecyl)-6-chromanol
HSDB 2556
E-Vimin
EINECS 200-412-2
NSC 20812
(all-R)-alpha-Tocopherol
Evitaminum
Almefrol
E307
Emipherol
Etamican
Vitayonon
Ilitia
(+-)-Med-E
UNII-N9PR3490H9
(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol
H4N855PNZ1
BPBio1_000362
18920-62-2
Vitaplex E
Covi-ox
DTXSID0026339
E 307
.ALPHA.-TOCOPHEROL, D-
Spavit E
EC 200-412-2
alpha-D-Tocopherol
Endo E
N9PR3490H9
Vita E
EINECS 215-798-8
EINECS 218-197-9
a-Vitamin E
NSC 82623
(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-ol
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2R)-
(+-)-alpha-Tocopherol
C29H50O2
(+/-)-alpha-Tocopherol
rel-alpha-Vitamin E
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2R)-rel-
ALPHA-TOCOPHEROL ACETATE
Alpha-Tocopherol Acetate is a natural product found in Myriactis humilis, Senegalia polyacantha, and Senegalia catechu with data available.
Alpha-Tocopherol Acetate is a natural tocopherol and one of the most potent antioxidant tocopherols.


CAS Number: 7695-91-2
CAS Number: 58-95-7 RRR-α-isomer
EC Number: 231-710-0
MDL number: MFCD00072042
Chemical formula: C31H52O3



SYNONYMS:
Vitamin E acetate, alpha-Tocopherol acetate, 58-95-7, Tocopherol acetate, Alfacol, Tocopheryl acetate, D-alpha-tocopherol acetate, D-ALPHA-TOCOPHERYL ACETATE, Ecofrol, Contopheron, Tofaxin, Econ, Ephynal acetate, Tokoferol acetate, Evipherol, Fertilvit, Tocopherex, Tocophrin, Erevit, Gevex, (+)-alpha-Tocopherol acetate, Combinal E, Epsilan-M, E-Toplex, E-Ferol, Endo E Dompe, Ephynal, Spondyvit, Juvela, alpha-Tocopheryl acetate, Copherol 1250, Covitol 1100, Covitol 1360, Vitamin Ealpha acetate, Vitamin E acetate, d-, Nanotopes, Simmyungsaengmosu, NatAc, Tinoderm E, Natur-E granulate, DL-alpha-Tocopheryl acetate, Lutavit E 50, (+)-alpha-Tocopheryl acetate, CCRIS 4389, (R,R,R)-alpha-Tocopheryl acetate, C31H52O3, EINECS 200-405-4, UNII-A7E6112E4N, (+-)-alpha-Tocopherol acetate, 52225-20-4, D-alpha tocoferil acetate, alpha-Tocopherol acetate, all rac, (2R,4'R,8'R)-alpha-Tocopheryl acetate, A7E6112E4N, DL-alpha-Tocopherylacetate, d-Alpha Tocopheryl Acetate, .alpha.-Tocopherol acetate, alpha-Tocopherol acetate, (2R,4'R,8'R)-, EINECS 231-710-0, MFCD00072052, RRR-alpha-tocopheryl acetate, (+)-alfa-tocopherol acetate, alpha-tocopheryl acetate, D-, D-.alpha.-Tocopherol acetate, Tocopheryl acetate, D-alpha-, Vitamin E Acetate (D-form), UNII-9E8X80D2L0, Vectan (TN), BRN 0097512, CCRIS 6054, 54-22-8, DTXSID1031096, CHEBI:32321, 9E8X80D2L0, D-|A-Tocopherol acetate, Tocopherolacetate, alpha-, DL-alpha tocopheryl acetate, EINECS 257-757-7, MFCD00072042, T-3376, d-Vitamin E acetate, Tocopherol acetate [JAN], .alpha.-Tocopheryl acetate, Tocopherol acetate (JP17), Tocopheryl Acetate, d-Alpha, CHEMBL1047, NCGC00166253-02, SCHEMBL22298, 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-cromanyl acetate, (+)-, 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-, 6-Cromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, MLS001335985, MLS001335986, DTXCID601356, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (2R-(2*(4R*,8R*))), 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R*(4R*,8R*)]], 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl acetate, (2R-(2*(4R*,8R*))), DTXSID3021356, (+)-.alpha.-Tocopherol acetate, (+)-.alpha.-Tocopheryl acetate, DL-alpha-Tocopherylacetate (Vitamin E acetate), EC 231-710-0, Syntopherol acetate, HMS2230C20, 5-17-04-00169 (Beilstein Handbook Reference), Tox21_111491, Tox21_111564, Tox21_113467, Tox21_303444, ALPHA-TOCOPHEROL ACETATE, D-, ALPHA-TOCOPHEROL ACETATE. D-, LS-245, Rovimix E 50SD, (R,R,R)-.alpha.-Tocopheryl acetate, 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate, AKOS025117621, NSC 755840, NSC-755840, Tox21_113467_1, [(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate, 1406-70-8, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, acetate, (2R)-, .ALPHA.-TOCOPHEROL ACETATE, D-, CAS-58-95-7, NCGC00095255-08, NCGC00166253-01, NCGC00257504-01, DL--Tocopherol acetate, AS-13784, J24.807J, LS-39402, LS-53371, SMR000857327, CAS-52225-20-4, O-Acetyl-alpha-tocopherol, (2R,4'R,8'R)-.alpha.-Tocopheryl acetate, DL-alpha-Tocopherol acetate, >=96% (HPLC), Vitamin E acetate dl-form, 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, C13202, D01735, DL-alpha-Tocopherol acetate, analytical standard, [(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-yl] acetate, 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-b- enzopyran-6-ol, acetate, d,l-alpha-Tocopheryl acetate, Eusovit, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, 6-acetate, (2R)-, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, acetate, (2R)-rel-, D-.alpha.-Tocopheryl acetate, Alpha-tocopherol acetate, dl-, Q-201933, vitamin E acetate, (2R-(2R*(4R*,8R*)))-isomer, W-109259, ECA8C22F-B5D3-4B88-A9B7-AF6C600001BB, vitamin E acetate, ((2R*(4R*,8R*))-(+-))-isomer, DL-alpha-Tocopherol acetate, tested according to Ph.Eur., DTXCID60196594, OptoVit E, SynAC, Rovimix E 50, Alpha Tocopheryl Acetate, United States Pharmacopeia (USP) Reference Standard, alpha-Tocopherol acetate, European Pharmacopoeia (EP) Reference Standard, DL-alpha-Tocopherol acetate, certified reference material, TraceCERT(R), DL-alpha-Tocopherylacetate (Vitamin E acetate) 10 microg/mL in Acetonitrile, (+)-alpha-Tocopherol acetate, BioReagent, suitable for insect cell culture, ~1360 IU/g, (R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl acetate, 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-yl acetate #, Tocopheryl Acetate, a, Pharmaceutical Secondary Standard; Certified Reference Material, (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl acetate, (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-yl acetate, (2R*(4R*,8R*))-(1)-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate, [2R-[2R*(4R,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol acetate, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, 6-acetate, 2H-1-benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (2R-(2R*(4R*,8R*))), 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate,(2R*(4R*,8R*))-(+-)-, All-rac-alpha-tocopheryl acetate for peak identification, European Pharmacopoeia (EP) Reference Standard, Tocopheryl acetate,alpha, Alpha Tocopheryl Acetate, D-ALPHA TOCOFERIL ACETATE (M), UNII-WR1WPI7EW8, Copherol 12250, d-|ATocopheryl Acetate, O-Acetyl-|A-tocopherol, alpha-Tocopherylis acetas, AC1L3BMH, DL-|A-Tocopheryl acetate, .alpha.-tocopherol acetate, dl-, AC1Q1PB2, (+)-|A-Tocopherol acetate, (+)-|A-Tocopheryl Acetate, all-rac-|A-Tocopheryl acetate, DL-ALPHA-TOCOPHEROLACETATE, C31-H52-O3, (R,R,R)-|A-Tocopheryl Acetate, (2R,4'R,8'R)-alpha-Tocopherol acetate, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, acetate, (2R)-, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, acetate, (2R)-rel-, Tocopherol, acetate, Acetate, Tocopherol, ZINC4172337, alpha-tocopherylacetat, FT-0624407, a- tocopheryl acetate, D--Tocopherol acetate, (2R,4'R,8'R)-|A-Tocopherol Acetate, (2R,4'R,8'R)-|A-Tocopheryl Acetate, SC-16401, SC-18242, alpha Tocopherol Acetate, DSSTox_CID_1356, d alpha Tocopheryl Acetate, DL-alpha-Tocopherol acetate, 50% powder form, J10308, DL-alpha-Tocopherol acetate, EP/USP/FCC grade, DSSTox_RID_76104, DSSTox_RID_78863, DSSTox_GSID_21356, DSSTox_GSID_31096, Vitamin E acetate (unlabeled), VITAMIN E ALPHA ACETATE, (+)- alpha -Tocopherol acetate, TOCOPHERYL ACETATE,D-ALPHA, D-alpha-Tocopheryl acetate, 97%, MolPort-003-928-528, DL-alpha-Tocopheryl acetate, 98%, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl- 2-(4,8,12-trimethyltridecyl)-, acetate, 3, 4- dihydro- 2, 5, 7, 8- tetramethyl- 2- (4, 8, 12- trimethyltridecyl)- 2H- benzopyran- 6- yl acetate, HY-B1278, TOCOPHERYL ACETATE [WHO-DD], Vitamin E acetate, unspecified form, TOCOPHERYL ACETATE, alpha, D-, s3681, Vitamin E (alpha tocopherol acetate), 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol acetate, CCG-269474, CS-O-00415, DB14002, .ALPHA.-TOCOPHEROL ACETATE. D-, (+-)-alpha-Tocopherol Acetateacid ester, .ALPHA.-TOCOPHEROL ACETATE [MI], TOCOPHERYL ACETATE, .ALPHA., D-, (2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol 6-Acetate, [2R*(4R*,8R*)]-()-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate, 133-80-2, 2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-,6-acetate, (2R)-, AK176402, all-rac-2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yl acetate, ALPHA TOCOPHERYL ACETATE (USP-RS), RRR-ALPHA-TOCOPHERYL ACETATE [FCC], TOCOPHERYL ACETATE,D-ALPHA [VANDF], CS-0013056, T2322, VITAMIN E (ALPHA-TOCOPHERYL ACETATE), A11606, D70796, alpha-TOCOPHEROL ACETATE, UNSPECIFIED FORM, EN300-7398027, A865381, Q364160, Z2681891483, UNII-WR1WPI7EW8 component ZAKOWWREFLAJOT-CEFNRUSXSA-N, Vitamin E acetate (dimethyl-13C2, acetyl-13C2, 99%; dimethyl-D6, 98%), (+)-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECYL)-6-CHROMANOL ACETATE, (2R-(2R*(4R*,8R*)))-3,4-DIHYDRO-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRI-DECYL)-2H-1-BENZOPYRAN-6-OL ACETATE, [2R*(4R*,8R*)]-(+-)-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate, 12741-00-3, 1407-18-7, 26243-95-8, 2H-1-Benzopiran-6-ol, 3,4-dihidro-2,5,7,8-tetrametil-2-[(4R,8R)-4,8,12-trimetiltridecil]-, 6-acetato, (2R)-rel-, 2H-1-benzopirano-6-ol, 3,4-dihidro-2,5,7,8-tetrametil-2-[(4R, 8R)-4,8,12-trimetiltridecil]-, 6-acetato, ( 2R)-, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl- 2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R(4R,8R)]]-, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R*(4R*,8R*)]-, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R*(4R*,8R*)]-(.+.)-, 2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-,acetate, (2R)-, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R*(4R*,8R*)]]-, Vitamin E acetate; 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-, α-Tocopherol acetate, (+)-α-Tocopherol acetate, (+)-α-Tocopheryl acetate, D-α-tocopherol acetate, D-α-tocopheryl acetate, Alfacol, Combinal E, Contopheron, E-Ferol, E-Toplex, Ecofrol, Econ, Endo E Dompe, Ephynal acetate, Eps, UNII-WR1WPI7EW8, Copherol 12250, d-|ATocopheryl Acetate, O-Acetyl-|A-tocopherol, alpha-Tocopherylis acetas, AC1L3BMH, DL-|A-Tocopheryl acetate, .alpha.-tocopherol acetate, dl-, AC1Q1PB2, (+)-|A-Tocopherol acetate, (+)-|A-Tocopheryl Acetate, all-rac-|A-Tocopheryl acetate, DL-ALPHA-TOCOPHEROLACETATE, C31-H52-O3, (R,R,R)-|A-Tocopheryl Acetate, (2R,4'R,8'R)-alpha-Tocopherol acetate, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, acetate, (2R)-, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, acetate, (2R)-rel-, Tocopherol, acetate, Acetate, Tocopherol, ZINC4172337, alpha-tocopherylacetat, FT-0624407, a- tocopheryl acetate, D--Tocopherol acetate, (2R,4'R,8'R)-|A-Tocopherol Acetate, (2R,4'R,8'R)-|A-Tocopheryl Acetate, SC-16401, SC-18242, alpha Tocopherol Acetate, DSSTox_CID_1356, d alpha Tocopheryl Acetate, DL-alpha-Tocopherol acetate, 50% powder form, J10308, DL-alpha-Tocopherol acetate, EP/USP/FCC grade, DSSTox_RID_76104, DSSTox_RID_78863, DSSTox_GSID_21356, DSSTox_GSID_31096, Vitamin E acetate (unlabeled), VITAMIN E ALPHA ACETATE, (+)- alpha -Tocopherol acetate, TOCOPHERYL ACETATE,D-ALPHA, D-alpha-Tocopheryl acetate, 97%, MolPort-003-928-528, DL-alpha-Tocopheryl acetate, 98%, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl- 2-(4,8,12-trimethyltridecyl)-, acetate, 3, 4- dihydro- 2, 5, 7, 8- tetramethyl- 2- (4, 8, 12- trimethyltridecyl)- 2H- benzopyran- 6- yl acetate, HY-B1278, TOCOPHERYL ACETATE [WHO-DD], Vitamin E acetate, unspecified form, TOCOPHERYL ACETATE, alpha, D-, s3681, Vitamin E (alpha tocopherol acetate), 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol acetate, CCG-269474, CS-O-00415, DB14002, .ALPHA.-TOCOPHEROL ACETATE. D-, (+/-)-alpha-Tocopherol Acetateacid ester, .ALPHA.-TOCOPHEROL ACETATE [MI], TOCOPHERYL ACETATE, .ALPHA., D-, (2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol 6-Acetate, [2R*(4R*,8R*)]-()-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate, 133-80-2, 2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-,6-acetate, (2R)-, AK176402, all-rac-2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yl acetate, ALPHA TOCOPHERYL ACETATE (USP-RS), RRR-ALPHA-TOCOPHERYL ACETATE [FCC], TOCOPHERYL ACETATE,D-ALPHA [VANDF], CS-0013056, T2322, VITAMIN E (ALPHA-TOCOPHERYL ACETATE), A11606, D70796, alpha-TOCOPHEROL ACETATE, UNSPECIFIED FORM, EN300-7398027, A865381, Q364160, Z2681891483, UNII-WR1WPI7EW8 component ZAKOWWREFLAJOT-CEFNRUSXSA-N, Vitamin E acetate (dimethyl-13C2, acetyl-13C2, 99%; dimethyl-D6, 98%), (+)-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECYL)-6-CHROMANOL ACETATE, (2R-(2R*(4R*,8R*)))-3,4-DIHYDRO-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRI-DECYL)-2H-1-BENZOPYRAN-6-OL ACETATE, [2R*(4R*,8R*)]-(+-)-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate, 12741-00-3, 1407-18-7, 26243-95-8, 2H-1-Benzopiran-6-ol, 3,4-dihidro-2,5,7,8-tetrametil-2-[(4R,8R)-4,8,12-trimetiltridecil]-, 6-acetato, (2R)-rel-, 2H-1-benzopirano-6-ol, 3,4-dihidro-2,5,7,8-tetrametil-2-[(4R, 8R)-4,8,12-trimetiltridecil]-, 6-acetato, ( 2R)-, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R(4R,8R)]]-, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R*(4R*,8R*)]-, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R*(4R*,8R*)]-(.+.)-, 2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-,acetate, (2R)-, 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R*(4R*,8R*)]]-, Vitamin E acetate; 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-, α-Tocopherol acetate, (+)-α-Tocopherol acetate, (+)-α-Tocopheryl acetate, D-α-tocopherol acetate, D-α-tocopheryl acetate, Alfacol, Combinal E, Contopheron, E-Ferol, E-Toplex, Ecofrol, Econ, Endo E Dompe, Ephynal acetate, Epsilan,



Alpha-Tocopherol Acetate, also known as a-tocopherol acetic acid, belongs to the class of organic compounds known as vitamin e compounds.
These are a group of fat-soluble compounds containing or derived either from a tocopherol or a tocotrienol skeleton.
Based on a literature review a significant number of articles have been published on alpha-Tocopherol acetate.


Alpha-Tocopherol Acetate belongs to the class of organic compounds known as vitamin e compounds.
These are a group of fat-soluble compounds containing or derived either from a tocopherol or a tocotrienol skeleton.
Alpha-Tocopherol Acetate, also known as a-tocopherol acetic acid, belongs to the class of organic compounds known as vitamin e compounds.


These are a group of fat-soluble compounds containing or derived either from a tocopherol or a tocotrienol skeleton.
Based on a literature review a significant number of articles have been published on Alpha-Tocopherol Acetate.
Alpha-Tocopherol Acetate is a natural product found in Myriactis humilis, Senegalia polyacantha, and Senegalia catechu with data available.


Alpha-Tocopherol Acetate is the acetate ester of a fat-soluble vitamin with potent antioxidant properties.
Considered essential for the stabilization of biological membranes (especially those with high amounts of polyunsaturated fatty acid), Alpha-Tocopherol Acetate is a generic name for a group of compounds known as tocopherols and tocotrienols (tocols).


Alpha-Tocopherol Acetate is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, resulting in a decrease in prostaglandin production.
Alpha-Tocopherol Acetate also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription.


Alpha-Tocopherol Acetate is a natural tocopherol and one of the most potent antioxidant tocopherols.
Alpha-Tocopherol Acetate exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus.
Alpha-Tocopherol Acetate has four methyl groups on the 6-chromanol nucleus.


The natural d form of Alpha-Tocopherol Acetate is more active than its synthetic dl-alpha-tocopherol racemic mixture.
Alpha-Tocopherol Acetate appears as odorless off-white crystals.
Alpha-Tocopherol Acetate is a tocol.


Alpha-Tocopherol Acetate, also known simply as tocopheryl acetate, is a synthetic form of vitamin E found in dietary supplements and skin care products.
Alpha-Tocopherol Acetate is considered the most stable and active form of vitamin E and the best option overall for treating vitamin E deficiency.
Alpha-Tocopherol Acetate is marketed to prevent several health conditions or diseases.


Yet, research on Alpha-Tocopherol Acetate and vitamin E supplementation, in general, has not proven many of these health claims.
Alpha-Tocopherol Acetate is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements.
Alpha-tocopherol acetate is subsequently most commonly indicated for dietary supplementation in individuals who may demonstrate a genuine deficiency in vitamin E.


Alpha-Tocopherol Acetate itself is naturally found in various foods, added to others, or used in commercially available products as a dietary supplement.
The recommended dietary allowances (RDAs) for Alpha-Tocopherol Acetate are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months, males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg (10.4 IU) in ages 4-8 years, males = 11 mg (16.4 IU) females = 11 mg (16.4 IU) in ages 9-13 years, males = 15 mg (22.4 IU) females = 15 mg (22.4 IU) pregnancy = 15 mg (22.4 IU) lactation = 19 mg (28.4 IU) in ages 14+ years 5.


Alpha-Tocopherol Acetate is also added to fortified foods, such as cereals, fruit juices, and many spreads.
You can check food labels to see if Alpha-Tocopherol Acetate has been added.
If you want to increase your Alpha-Tocopherol Acetate intake, you should start by first increasing your intake of these foods.


Alpha-Tocopherol Acetate is a specific form of vitamin E that’s often found in skin care products and dietary supplements.
Alpha-Tocopherol Acetate’s also known as tocopheryl acetate, tocopherol acetate, or vitamin E acetate.
Alpha-Tocopherol Acetate, also known as vitamin E acetate, is a form of vitamin E with D-Alpha Tocpheryl Acetate as the natural form and DL-Alpha Tocopheryl Acetate as the synthetic form.


Alpha-Tocopherol Acetate indicates the synthetic form where as D- indicates the natural form.
Alpha-Tocopherol Acetate is the ester of acetic acid and α-tocopherol.
Alpha-Tocopherol Acetate is known for its antioxidant properties.


Antioxidants help to protect your body from damaging compounds called free radicals.
Normally, free radicals form when your body converts food into energy.
However, free radicals can also come from UV light, cigarette smoke, and air pollution.


In nature, Alpha-Tocopherol Acetate comes in the form of tocopheryl or tocotrienol.
Both tocopheryl and tocotrienol have four forms, known as alpha, beta, gamma, and delta.
Alpha-tocopheryl (AT) is the most active form of vitamin E in humans.


Alpha-Tocopherol Acetate is more stable than Alpha-Tocopherol, meaning it can better withstand environmental stresses such as heat, air, and light.
This makes Alpha-Tocopherol Acetate ideal for use in supplements and fortified foods because it has a longer shelf life.



USES and APPLICATIONS of ALPHA-TOCOPHEROL ACETATE:
Alpha-Tocopherol Acetate has many proposed uses, primarily because of its antioxidant properties, which are thought to protect cells from free radicals.
In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of Alpha-Tocopherol Acetate and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol stereoisomers.


Moreover, RRR-alpha-tocopherol acetate is a relatively stabilized form of vitamin E that is most commonly used as a food additive when needed.
Alpha-tocopherol acetate is subsequently most commonly indicated for dietary supplementation in individuals who may demonstrate a genuine deficiency in vitamin E.


Vitamin E itself is naturally found in various foods, added to others, or used in commercially available products as a dietary supplement.
In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol stereoisomers.


Moreover, RRR-alpha-tocopherol acetate is a relatively stabilized form of vitamin E that is most commonly used as a food additive when needed 2.
Although there is widespread use of Alpha-Tocopherol Acetate as a topical medication, with claims for improved wound healing and reduced scar tissue, reviews have repeatedly concluded that there is insufficient evidence to support these claims.


There are reports of Alpha-Tocopherol Acetate-induced allergic contact dermatitis from use of vitamin E derivatives such as tocopheryl linoleate and tocopherol acetate in skin care products.
Due to its higher stability, Alpha-Tocopherol Acetate is also used in vitamin E dietary supplements.


When taken orally, Alpha-Tocopherol Acetate is converted to AT within the intestine.
Alpha-Tocopherol Acetate is in most multi-vitamins, so be sure to check how much is in your multi-vitamin if you take one, before adding a supplement.
Alpha-Tocopherol Acetate usually needs to be used with other vitamins and minerals to have a beneficial effect.
Alpha-Tocopherol Acetate is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements.


-Use in cosmetics
Alpha-Tocopherol Acetate is often used in dermatological products such as skin creams.
Alpha-Tocopherol Acetate is not oxidized and can penetrate through the skin to the living cells, where about 5% is converted to free tocopherol.

Alpha-Tocopherol Acetate claims are made for beneficial antioxidant effects.
Alpha-Tocopherol Acetate is used as an alternative to tocopherol itself because the phenolic hydroxyl group is blocked, providing a less acidic product with a longer shelf life.

It is believed that the acetate is slowly hydrolyzed after Alpha-Tocopherol Acetate is absorbed into the skin, regenerating tocopherol and providing protection against the sun's ultraviolet rays.
Alpha-Tocopherol Acetate was first synthesized in 1963 by workers at Hoffmann-La Roche.


-Marketed but unproven uses of Alpha-Tocopherol Acetate include:
*Reducing inflammation,
*Preventing heart disease,
*Preventing cancer,
*Promoting wound healing,
*Slowing cognitive decline,
*Slowing the progression of macular degeneration (eye disease affecting central vision),


-Uses of Tocopheryl Acetate
Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietitian, pharmacist, or healthcare provider.
No supplement is intended to treat, cure, or prevent disease.



WHERE CAN I FIND ALPHA-TOCOPHEROL ACETATE?
*Cosmetics and supplements
You’ll find Alpha-Tocopherol Acetate in a variety of skin care products.
The antioxidant properties of Alpha-Tocopherol Acetate can help to prevent damage to skin caused by free radicals from UV exposure.
Alpha-Tocopherol Acetate may also have an anti-inflammatory effect on the skin.



ALTERNATIVE PARENTS OF ALPHA-TOCOPHEROL ACETATE:
*Diterpenoids
*1-benzopyrans
*Alkyl aryl ethers
*Benzenoids
*Carboxylic acid esters
*Oxacyclic compounds
*Monocarboxylic acids and derivatives
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS OF ALPHA-TOCOPHEROL ACETATE:
*Diterpenoid
*Chromane
*Benzopyran
*1-benzopyran
*Alkyl aryl ether
*Benzenoid
*Carboxylic acid ester
*Carboxylic acid derivative
*Oxacycle
*Organoheterocyclic compound
*Ether
*Monocarboxylic acid or derivatives
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Carbonyl group
*Organooxygen compound
*Aromatic heteropolycyclic compound



FOODS, ALPHA-TOCOPHEROL ACETATE:
In addition to dietary supplements and cosmetic products, you can find Alpha-Tocopherol Acetate in the following foods:
**green leafy vegetables, such as broccoli and spinach
**oils, such as sunflower oil, wheat germ oil, and corn oil
**sunflower seeds
**nuts, such as almonds and peanuts
**whole grains
**fruits, such as kiwi and mango



POTENTIAL BENEFITS OF ALPHA-TOCOPHEROL ACETATE:
Using AT on the skin, especially with vitamin C, helps to prevent UV damage to the skin.
In a review of studies, the Linus Pauling Institute at Oregon State University found that using AT with vitamin C on the skin decreased sunburned cells, DNA damage, and skin pigmentation following UV exposure.

However, AT is less stable in the environment than Alpha-Tocopherol Acetate, which makes it harder to store.
While Alpha-Tocopherol Acetate is less sensitive to heat and light than AT is, there’s less conversion of ATA to the active AT form within the skin.
This is because the cells in the upper layer of your skin are much less metabolically active.
As a result, using cosmetic products containing Alpha-Tocopherol Acetate on your skin may not be very effective.



CHEMISTRY OF ALPHA-TOCOPHEROL ACETATE:
At room temperature, Alpha-Tocopherol Acetate is a fat-soluble liquid.
Alpha-Tocopherol Acetate has 3 chiral centers and thus 8 stereoisomers.

Alpha-Tocopherol Acetate is made by esterifying α-tocopherol with acetic acid.
2R,4R,8R-isomer, also known as RRR-α-tocopheryl acetate, is the most common isomer used for various purposes.
This is because α-tocopherol occurs in nature primarily as RRR-α-tocopherol.

Alpha-Tocopherol Acetate does not boil at atmospheric pressure and begins to degrade at 240 °C.
Alpha-Tocopherol Acetate can be vacuum distilled: it boils at 184 °C at 0.01 mmHg, at 194 °C (0.025 mmHg) and at 224 °C (0.3 mmHg).
In practice, Alpha-Tocopherol Acetate is not degraded notably by air, visible light or UV-radiation.

Alpha-Tocopherol Acetate has a refractive index of 1.4950–1.4972 at 20 °C.
Alpha-Tocopherol Acetate is hydrolyzed to α-tocopherol and acetic acid under suitable conditions or when ingested by people.



PHYSICAL and CHEMICAL PROPERTIES of ALPHA-TOCOPHEROL ACETATE:
Chemical formula: C31H52O3
Molar mass: 472.743 g/mol
Appearance: pale yellow, viscous liquid
Melting point: –27.5 °C
Boiling point: 240 °C decays without boiling
Solubility in water: insoluble
Solubility: soluble in acetone, chloroform, diethyl ether; poorly soluble in ethanol
Molecular Weight: 472.7 g/mol
XLogP3-AA: 10.8
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 14

Exact Mass: 472.39164552 g/mol
Monoisotopic Mass: 472.39164552 g/mol
Topological Polar Surface Area: 35.5Ų
Heavy Atom Count: 34
Formal Charge: 0
Complexity: 602
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 3
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Appearance Form: liquid
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: 224 °C at 0,4 hPa
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available

Density: No data available
Relative density: 0,95 - 0,964 at 25 °C
Water solubility: 0,0008 g/l at 20 °C slightly soluble
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: 5706 mm2/s at 20 °C
Viscosity, dynamic: 701 mPa.s at 40 °C
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Water Solubility: 2.9e-06 g/L

logP: 9.19
logP: 10.42
logS: -8.2
pKa (Strongest Basic): -4.9
Physiological Charge: 0
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 0
Polar Surface Area: 35.53 Ų
Rotatable Bond Count: 14
Refractivity: 144.53 m³·mol⁻¹
Polarizability: 60.23 ų
Number of Rings: 2
Bioavailability: No

Rule of Five: No
Ghose Filter: No
Veber's Rule: No
MDDR-like Rule: No
Chemical Formula: C31H52O3
IUPAC name: 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yl acetate
InChI Identifier: InChI=1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3
InChI Key: ZAKOWWREFLAJOT-UHFFFAOYSA-N
Isomeric SMILES: CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=C(C)C(OC(C)=O)=C(C)C(C)=C2O1
Average Molecular Weight: 472.7428
Monoisotopic Molecular Weight: 472.39164553
IUPAC Name: [(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate
Molecular Weight: 472.74
Molecular Formula: C31H52O3

Canonical SMILES: CC1=C(C(=C(C2=C1OC(CC2)(C)CCCC(C)CCCC(C)CCCC(C)C)C)OC(=O)C)C
InChI: InChI=1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1
InChIKey: ZAKOWWREFLAJOT-CEFNRUSXSA-N
Boiling Point: 224°C0.3mm Hg(lit.)
Melting Point: 28°C
Flash Point: >230 °F
Density: 0.953 g/mL at 25 °C(lit.)
Solubility: Soluble in Chloroform (Slightly), Ethanol (Slightly, Sonicated), Ethyl Acetate (Slightly)
Appearance: Colourless to Light Yellow Thick Oil to Low-Melting Solid
Application: anticoagulant
Storage: -20°C
Assay: 0.9999
EINECS: 200-405-4
MDL: MFCD00072052
Refractive Index: 1.494-1.498
Stability: Stable.

Chemical Formula: C31H52O3
Molar Mass: 472.743 g/mol
Appearance: Pale yellow, viscous liquid
Melting Point: –27.5 °C
Boiling Point: 240 °C (decays without boiling)
Solubility in Water: Insoluble
Solubility: Soluble in acetone, chloroform, diethyl ether; poorly soluble in ethanol
Chemical Formula: C31H52O3
Average Molecular Weight: 472.7428
Monoisotopic Molecular Weight: 472.39164553
IUPAC Name: 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yl acetate
Traditional Name: Tocopheryl acetate

CAS Registry Number: 58-95-7
SMILES: CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=C(C)C(OC(C)=O)=C(C)C(C)=C2O1
InChI Identifier: InChI=1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3
InChI Key: ZAKOWWREFLAJOT-UHFFFAOYSA-N
Water Solubility: 2.9e-06 g/L
logP: 9.19
logP: 10.42
logS: -8.2
pKa (Strongest Basic): -4.9
Physiological Charge: 0
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 0
Polar Surface Area: 35.53 Ų
Rotatable Bond Count: 14
Refractivity: 144.53 m³·mol⁻¹

Polarizability: 60.23 ų
Number of Rings: 2
Bioavailability: No
Rule of Five: No
Ghose Filter: No
Veber's Rule: No
MDDR-like Rule: No
Chemical Formula: C31H52O3
IUPAC Name: 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yl acetate
InChI Identifier: InChI=1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3
InChI Key: ZAKOWWREFLAJOT-UHFFFAOYSA-N
Isomeric SMILES: CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=C(C)C(OC(C)=O)=C(C)C(C)=C2O1
Average Molecular Weight: 472.7428
Monoisotopic Molecular Weight: 472.39164553



FIRST AID MEASURES of ALPHA-TOCOPHEROL ACETATE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ALPHA-TOCOPHEROL ACETATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ALPHA-TOCOPHEROL ACETATE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ALPHA-TOCOPHEROL ACETATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Respiratory protection:
Not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ALPHA-TOCOPHEROL ACETATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
*Storage stability:
Recommended storage temperature: 2 - 8 °C



STABILITY and REACTIVITY of ALPHA-TOCOPHEROL ACETATE:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available

ALPHA-TOCOPHEROL ACETATE
Alpha-tocopherol Acetate is a chemical compound that consists of acetic acid and tocopherol (vitamin E).
Alpha-tocopherol Acetate, also known as vitamin E acetate, is a synthetic form of vitamin E.
Alpha-tocopherol Acetate is the ester of acetic acid and α-tocopherol.


CAS Number: 7695-91-2
CAS Number: 58-95-7 RRR-α-isomer
MDL number: MFCD00072042
Chemical formula: C31H52O3


Alpha-tocopherol Acetate is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements.
In particular, Alpha-tocopherol Acetate (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol stereoisomers.


Moreover, Alpha-tocopherol Acetate is a relatively stabilized form of vitamin E that is most commonly used as a food additive when needed.
Nevertheless, Alpha-tocopherol Acetate is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals.


This biologic action of Alpha-tocopherol Acetate consequently continues to generate ongoing interest and study in whether or not its antioxidant abilities may be used to help assist in preventing or treating a number of different conditions like cardiovascular disease, ocular conditions, diabetes, cancer and more.


Alpha-tocopherol Acetate is more resistant to oxidation during storage than unesterified tocopherols.
The bioavailability of alpha-tocopherol from alpha-tocopheryl acetate is roughly equivalent to that of free alpha-tocopherol.
Alpha-tocopherol Acetate belongs to the class of organic compounds known as vitamin e compounds.


These are a group of fat-soluble compounds containing or derived either from a tocopherol or a tocotrienol skeleton.
DL-α-Tocopherol acetate is the ester form of Alpha-tocopherol Acetate.
Tocopherols are a series of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring.


Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by humans.
Alpha-tocopherol Acetate is a natural phenol found in the herbs of Isodon adenantha, it exhibits the activity of anticoagulant and has high biological activity and chemical stability.


At lower level (200 mg kg(-1) flesh), Alpha-tocopherol Acetate reduces substantially lipid peroxidation.
Alpha-tocopherol Acetate, also known as a-tocopherol acetic acid, belongs to the class of organic compounds known as vitamin e compounds.
These are a group of fat-soluble compounds containing or derived either from a tocopherol or a tocotrienol skeleton.


Based on a literature review a significant number of articles have been published on alpha-Tocopherol acetate.
Alpha-tocopherol Acetate appears as odorless off-white crystals. Darkens at 401 °F.
Alpha-tocopherol Acetate is a tocol.


Alpha-tocopherol Acetate is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements.
In particular, Alpha-tocopherol Acetate (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol stereoisomers.


Moreover, Alpha-tocopherol Acetate is a relatively stabilized form of vitamin E that is most commonly used as a food additive when needed.
Alpha-tocopherol acetate is subsequently most commonly indicated for dietary supplementation in individuals who may demonstrate a genuine deficiency in vitamin E.


Alpha-tocopherol Acetate itself is naturally found in various foods, added to others, or used in commercially available products as a dietary supplement.
The recommended dietary allowances (RDAs) for Alpha-tocopherol Acetate are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months, males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg (10.4 IU) in ages 4-8 years, males = 11 mg (16.4 IU) females = 11 mg (16.4 IU) in ages 9-13 years, males = 15 mg (22.4 IU) females = 15 mg (22.4 IU) pregnancy = 15 mg (22.4 IU) lactation = 19 mg (28.4 IU) in ages 14+ years.


Most individuals obtain adequate Alpha-tocopherol Acetate intake from their diets; genuine vitamin E deficiency is considered to be rare.
Nevertheless, Alpha-tocopherol Acetate is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals.


This biologic action of Alpha-tocopherol Acetate consequently continues to generate ongoing interest and study in whether or not its antioxidant abilities may be used to help assist in preventing or treating a number of different conditions like cardiovascular disease, ocular conditions, diabetes, cancer and more.


At the moment however, there exists a lack of formal data and evidence to support any such additional indications for Alpha-tocopherol Acetate use.
Alpha-tocopherol Acetate is a natural product found in Senegalia catechu, Myriactis humilis, and Senegalia polyacantha with data available.
Alpha-tocopherol Acetate and one of the most potent antioxidant tocopherols.


Alpha-tocopherol Acetate exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus.
Alpha-tocopherol Acetate has four methyl groups on the 6-chromanol nucleus.
The natural d form of Alpha-tocopherol Acetate is more active than its synthetic dl-alpha-tocopherol racemic mixture.


Alpha-tocopherol Acetate, also known simply as tocopheryl acetate, is a synthetic form of vitamin E found in dietary supplements and skin care products.
Alpha-tocopherol Acetate is considered the most stable and active form of vitamin E and the best option overall for treating vitamin E deficiency.
Alpha-tocopherol Acetateis a specific form of vitamin E that’s often found in skin care products and dietary supplements.


Alpha-tocopherol Acetate’s also known as tocopheryl acetate, tocopherol acetate, or vitamin E acetate.
Alpha-tocopherol Acetate is known for its antioxidant properties.
Antioxidants help to protect your body from damaging compounds called free radicals.


Normally, free radicals form when your body converts food into energy.
However, free radicals can also come from UV light, cigarette smoke, and air pollution.
In nature, Alpha-tocopherol Acetate comes in the form of tocopheryl or tocotrienol.


Both tocopheryl and tocotrienol have four forms, known as alpha, beta, gamma, and delta.
Alpha-tocopheryl (AT) is the most active form of Alpha-tocopherol Acetate in humans.
Alpha-tocopherol Acetate is more stable than AT, meaning it can better withstand environmental stresses such as heat, air, and light.


This makes Alpha-tocopherol Acetate ideal for use in supplements and fortified foods because it has a longer shelf life.
Alpha-tocopherol Acetate is a form of vitamin E.
Alpha-tocopherol Acetate can be obtained through dietary sources.


Alpha-tocopherol Acetate is an orally active synthetic form of vitamin E.
Alpha-tocopherol Acetate is the ester of acetic acid and α-tocopherol.
Alpha-tocopherol Acetate is water-insoluble vitamin E formed by esterification of acetic acid & tocopherol.


Alpha-tocopherol Acetate is a water-insoluble vitamin E formed by esterification of acetic acid & tocopherol.
Alpha-tocopherol Acetate provides excellent antioxidant activity on the skin but less so in cosmetic products since enzymes need first to cleave off acetate to form active vitamin E.


Alpha-tocopherol Acetate, also known as vitamin E acetate, is a common vitamin supplement with the molecular formula C31H52O3 (for 'α' form).
Alpha-tocopherol Acetate is the ester of acetic acid and tocopherol (vitamin E).
When taken orally, Alpha-tocopherol Acetate is converted to AT within the intestine.


Alpha-tocopherol Acetate is also added to fortified foods, such as cereals, fruit juices, and many spreads.
You can check food labels to see if Alpha-tocopherol Acetate has been added.
If you want to increase your Alpha-tocopherol Acetate intake, you should start by first increasing your intake of these foods.


It is less stable in the environment than Alpha-tocopherol Acetate, which makes it harder to store.
While Alpha-tocopherol Acetate is less sensitive to heat and light than AT is, there’s less conversion of ATA to the active AT form within the skin.
This is because the cells in the upper layer of your skin are much less metabolically active.


As a result, using cosmetic products containing Alpha-tocopherol Acetate on your skin may not be very effective.
This is supported by a study from 2011 published in the Medical Principles and Practice journal.
They found that, while there was Alpha-tocopherol Acetate in the upper levels of the skin after using the product, there was no active AT.


While there are many studies on the potential benefits of AT, studies on the benefits of Alpha-tocopherol Acetate are limited.
The results of these studies on Alpha-tocopherol Acetate are mixed.
Alpha-tocopherol Acetate usually needs to be used with other vitamins and minerals to have a beneficial effect.


In another review of studies, the Linus Pauling Institute found that consuming Alpha-tocopherol Acetate along with other antioxidant supplements had no effect on either the development or prevention of cataracts.


Regarding the benefits of Alpha-tocopherol Acetate, study results have been mixed on whether they’re beneficial for the following conditions:
*coronary heart disease
*cancer
*cognitive decline, such as Alzheimer’s disease


Alpha-tocopherol Acetate is a fat-soluble vitamin and is one of the most important antioxidants.
Alpha-tocopherol Acetate is soluble in organic solvent such as fat and ethanol, insoluble in water, stable to heat and acid, unstable to alkali, sensitive to oxygen and insensitive to heat, but the activity of vitamin E is significantly reduced when fried.


Alpha-tocopherol Acetate is a form of vitamin E, mainly used for livestock and poultry due to vitamin E deficiency caused by muscle dystrophy or white muscle disease, to prevent livestock and poultry reproductive dysfunction and nervous system dysfunction, etc.
Alpha-tocopherol Acetate, also known as vitamin E1, is one of several forms of vitamin E.
Alpha-tocopherol Acetate appears as a light yellow, viscous, odorless, oily liquid that deteriorates on exposure to light.



USES and APPLICATIONS of ALPHA-TOCOPHEROL ACETATE:
Alpha-tocopherol Acetate is a biocatalyst, which can regulate carbohydrate metabolism, promote the maturation of gonads and reproductive function, is closely related to the reproduction of livestock and poultry, and plays a role in promoting conception and preventing miscarriage.
Sufficient Alpha-tocopherol Acetate acetate added to feed can promote animal system development, reduce morbidity, mortality, and increase animal weight gain.


Alpha-tocopherol Acetate can also accelerate the synthesis of gonadotropins in the anterior pituitary of animals and improve reproductive performance, thereby increasing the number of litters and eggs in animals.
Cosmetics & Personal Care uses of Alpha-tocopherol Acetate: Anti-Aging Care, Anti-Wrinkle Care, Daily Care, Skin Protection, Sun & After-sun Care, Hair Care, Hand & Nail Care, Men Care, etc.


Animal Nutrition uses of Alpha-tocopherol Acetate: Pet Food, Feed, Cereals, etc.
Alpha-tocopherol Acetate’s the most commonly used version of pure vitamin E in cosmetics.
Alpha-tocopherol Acetate is a powerful inhibitor of the proliferation of estrogen receptor positive and estrogen receptor negative human breast cancer cell lines in a dose dependent manner in vitro.


Alpha-tocopherol Acetate is used Inhibition.
Food & Nutrition uses of Alpha-tocopherol Acetate:
Oils & Fats, Confectionery & Bakery, Snacks & Cereals, Cocoa & Chocolate, Spices & Condiments, Sauces & Dressings, Meat Products, Baby Food, Soft Capsules,

Dietetic Products, Nutraceutical Formulations, Food Supplements, etc.
Alpha-tocopherol Acetate is marketed to prevent several health conditions or diseases.
Alpha-tocopherol Acetate is used should be individualized and vetted by a healthcare professional, such as a registered dietitian, pharmacist, or healthcare provider.


Alpha-tocopherol Acetate has many proposed uses, primarily because of its antioxidant properties, which are thought to protect cells from free radicals.
Alpha-tocopherol Acetate is used Reducing inflammation, Preventing heart disease, Preventing cancer, Promoting wound healing, Slowing cognitive decline, Slowing the progression of macular degeneration (eye disease affecting central vision).


However, there is not enough evidence to support most of these claims.
Many studies have found Alpha-tocopherol Acetate to be ineffective for these uses.
Due to its higher stability, Alpha-tocopherol Acetate is also used in vitamin E dietary supplements.


Alpha-tocopherol Acetate is used as an alternative to free tocopherol because it is more stable in formulation.
Alpha-tocopherol Acetate in our products serves as an antioxidant for the product and for its skin conditioning properties.
Alpha-tocopherol Acetate is used as an antioxidant in oils and vitamin E supplements.


The most common form of Alpha-tocopherol Acetate is used in sunscreen and skin care products.
Alpha-tocopherol Acetate is used as a nutritional supplement.
Alpha-tocopherol Acetate is permitted for use as an inert ingredient in non-food pesticide products


Alpha-tocopherol Acetate is obtained from wheat germ oil or by synthesis, biologically exhibits the most vitamin E activity of the α-tocopherols, and is an antioxidant retarding rancidity by interfering with the autoxidation of fats.
Alpha-tocopherol Acetate is found in foods such as vegetable oils and shortening, meat, eggs, milk, and leafy vegetables.


Alpha-tocopherol Acetate is important for many processes in the body.
Alpha-tocopherol Acetate is used to treat Vitamin E deficiency.
Alpha-tocopherol Acetate is available as a liquid and as liquid-filled capsules.


Alpha-tocopherol Acetate is used for external use only.
Alpha-tocopherol Acetate can be used for research of the susceptibility of farmed fish to infectious diseases.
Alpha-tocopherol Acetate is used in all kinds of skin care products including sun care & makeup products.


Alpha-tocopherol Acetate can improve the appearance of aged skin making it look visibly younger.
Alpha-tocopherol Acetate acetate was used as a vitamin E supplement for studying whether the addition of an antioxidant or vitamin E in the diet of rats with dextran sulfate sodium (DSS)-induced colitis can reduce detrimental impact of inflammatory bowel disease.


Alpha-tocopherol Acetate is often used in dermatological products such as skin creams.
Alpha-tocopherol Acetate is not oxidized and can penetrate through the skin to the living cells, where about 5% is converted to free tocopherol. Alpha-tocopherol Acetate claims are made for beneficial antioxidant effects.


Alpha-tocopherol Acetate is used as an alternative to tocopherol itself because the phenolic hydroxyl group is blocked, providing a less acidic product with a longer shelf life.
It is believed that Alpha-tocopherol Acetate is slowly hydrolyzed after it is absorbed into the skin, regenerating tocopherol and providing protection against the sun's ultraviolet rays.


Although there is the widespread use of Alpha-tocopherol Acetate as a topical medication, with claims for improved wound healing and reduced scar tissue, reviews have repeatedly concluded that there is insufficient evidence to support these claims.
Alpha-tocopherol Acetate has moisturizing, soothing, and calming properties on the skin.


-Use in cosmetics:
Alpha-tocopherol Acetate is often used in dermatological products such as skin creams.
Alpha-tocopherol Acetate is not oxidized and can penetrate through the skin to the living cells, where about 5% is converted to free tocopherol. Claims are made for beneficial antioxidant effects.
Alpha-tocopherol Acetate is used as an alternative to tocopherol itself because the phenolic hydroxyl group is blocked, providing a less acidic product with a longer shelf life.

Alpha-tocopherol Acetate is believed that the acetate is slowly hydrolyzed after it is absorbed into the skin, regenerating tocopherol and providing protection against the sun's ultraviolet rays.
Alpha-tocopherol Acetate was first synthesized in 1963 by workers at Hoffmann-La Roche.



BENEFITS OF ALPHA-TOCOPHEROL ACETATE:
*Higher bioavailability than Synthetic Vitamin E
*Protects cell membranes and strengthens the immune system
*Reduces the risk of certain diseases
*Possibility of declaring “Source of Vitamin E” in packaging
*Fights oxidative stress by blocking free radicals
*Increases skin hydration and prevents appearance of wrinkles
*It has anti-inflammatory and healing properties
*Acts as natural barrier against UV rays and toxins
*Promotes hair growth and improves hair’s appearance
*Protects the animal during the gestation period
*Prevents the loss of nutritional value of fatty acids
*Certificates: Kosher, Halal, Ecocert, Cosmos



FUNCTIONS AND APPLICATIONS OF ALPHA-TOCOPHEROL ACETATE:
1. Promote the secretion of sex hormones, so that men's sperm vitality and quantity increased; increase female estrogen concentration, increase fertility, prevent miscarriage.
2. Suppresses the lipid peroxide reaction in the eye's lens, dilates peripheral blood vessels and improves blood circulation.

3. Alpha-tocopherol Acetate can be used as an antioxidant.
Alpha-tocopherol Acetate helps prevent the oxidation of polyunsaturated fatty acids and phospholipids, so it can maintain the integrity of the cell membrane.
4. Alpha-tocopherol Acetate can protect vitamin A from oxidative damage and enhance its effect.

5. Alpha-tocopherol Acetate and iodine compounds have been proven to prevent vitamin E deficiency-related symptoms.
6. Alpha-tocopherol Acetate prevents the excessive agglutination of platelets and improves the stability of red blood cell membranes and the synthesis of red blood cells.



FOODS, ALPHA-TOCOPHEROL ACETATE:
In addition to dietary supplements and cosmetic products, you can find Alpha-tocopherol Acetate in the following foods:
*green leafy vegetables, such as broccoli and spinach
*oils, such as sunflower oil, wheat germ oil, and corn oil
*sunflower seeds
*nuts, such as almonds and peanuts
*whole grains
*fruits, such as kiwi and mango



CHEMISTRY OF ALPHA-TOCOPHEROL ACETATE:
At room temperature, Alpha-tocopherol Acetate is a fat-soluble liquid.
Alpha-tocopherol Acetate has 3 chiral centers and thus 8 stereoisomers.
Alpha-tocopherol Acetate is made by esterifying α-tocopherol with acetic acid.

2R,4R,8R-isomer, also known as RRR-Alpha-tocopherol Acetate, is the most common isomer used for various purposes.
This is because Alpha-tocopherol Acetate occurs in nature primarily as RRR-α-tocopherol.
Alpha-tocopherol Acetate does not boil at atmospheric pressure and begins to degrade at 240 °C.
Alpha-tocopherol Acetate can be vacuum distilled: it boils at 184 °C at 0.01 mmHg, at 194 °C (0.025 mmHg) and at 224 °C (0.3 mmHg).

In practice, Alpha-tocopherol Acetate is not degraded notably by air, visible light or UV-radiation.
Alpha-tocopherol Acetate has a refractive index of 1.4950–1.4972 at 20 °C.
Alpha-tocopherol Acetate is hydrolyzed to α-tocopherol and acetic acid under suitable conditions or when ingested by people.



BIOCHEM/PHYSIOL ACTIONS OF ALPHA-TOCOPHEROL ACETATE:
Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage.
Alpha-tocopherol Acetate is the form of tocopherol preferentially absorbed by Homosapiens.
Alpha-tocopherol Acetate can inhibit oxidation of linoleate.
Alpha-tocopherol Acetate is also known as a radical-chain breaker due to its anti-oxidant property.



BENEFITS OF ALPHA-TOCOPHEROL ACETATE:
Alpha-tocopherol Acetate provides excellent antioxidant activity on the skin but less so in cosmetic products since enzymes need first to cleave off acetate to form active vitamin E
Alpha-tocopherol Acetate has moisturizing, soothing, and calming properties on the skin
Alpha-tocopherol Acetate can improve the appearance of aged skin making it look visibly younger



THERAPEUTIC INDICATIONS OF ALPHA-TOCOPHEROL ACETATE:
For children Alpha-tocopherol Acetate is used to treat hemolytic jaundice, increased capillary permeability in infants, malnutrition, rickets, developmental disorders, systemic connective tissue diseases (scleroderma, juvenile rheumatoid arthritis), hypochromic anemia.
Alpha-tocopherol Acetate is used in the complex therapy of peripheral vascular disease, atherosclerosis, myocardial dystrophy, hypertension, allergies, and ulcerative skin lesions, psoriasis, endocrine diseases of the thyroid gland, diabetes, periodontal disease, pathologies requiring antioxidant therapy.



IS ALPHA-TOCOPHEROL ACETATE THE RIGHT OPTION FOR ME?
Alpha-tocopherol Acetate is food-grade and has been recognized by the Food and Drug Administration as GRAS (generally recognized as safe).



WHERE CAN I FIND ALPHA-TOCOPHEROL ACETATE?
Cosmetics and supplements
You’ll find Alpha-tocopherol Acetate in a variety of skin care products.
The antioxidant properties of Alpha-tocopherol Acetate can help to prevent damage to skin caused by free radicals from UV exposure.
Alpha-tocopherol Acetate may also have an anti-inflammatory effect on the skin.



ALTERNATIVE PARENTS OF ALPHA-TOCOPHEROL ACETATE:
*Diterpenoids
*1-benzopyrans
*Alkyl aryl ethers
*Benzenoids
*Carboxylic acid esters
*Oxacyclic compounds
*Monocarboxylic acids and derivatives
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS OF ALPHA-TOCOPHEROL ACETATE:
*Diterpenoid
*Chromane
*Benzopyran
*1-benzopyran
*Alkyl aryl ether
*Benzenoid
*Carboxylic acid ester
*Carboxylic acid derivative
*Oxacycle
*Organoheterocyclic compound
*Ether
*Monocarboxylic acid or derivatives
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Carbonyl group
*Organooxygen compound
*Aromatic heteropolycyclic compound



PHYSICAL and CHEMICAL PROPERTIES of ALPHA-TOCOPHEROL ACETATE:
Chemical formula: C31H52O3
Molar mass: 472.743 g/mol
Appearance: pale yellow, viscous liquid
Melting point: –27.5 °C
Boiling point: 240 °C decays without boiling
Solubility in water: insoluble
Solubility: soluble in acetone, chloroform, diethyl ether; poorly soluble in ethanol
Molecular Weight: 472.7 g/mol
XLogP3-AA: 10.8
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 14
Exact Mass: 472.39164552 g/mol
Monoisotopic Mass: 472.39164552 g/mol
Topological Polar Surface Area: 35.5Ų
Heavy Atom Count: 34
Formal Charge: 0
Complexity: 602
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 3
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Appearance Form: liquid
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: 224 °C at 0,4 hPa
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Density: No data available
Relative density: 0,95 - 0,964 at 25 °C
Water solubility: 0,0008 g/l at 20 °C slightly soluble
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: 5706 mm2/s at 20 °C
Viscosity, dynamic: 701 mPa.s at 40 °C
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Water Solubility: 2.9e-06 g/L

logP: 9.19
logP: 10.42
logS: -8.2
pKa (Strongest Basic): -4.9
Physiological Charge: 0
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 0
Polar Surface Area: 35.53 Ų
Rotatable Bond Count: 14
Refractivity: 144.53 m³·mol⁻¹
Polarizability: 60.23 ų
Number of Rings: 2
Bioavailability: No
Rule of Five: No
Ghose Filter: No
Veber's Rule: No
MDDR-like Rule: No
Chemical Formula: C31H52O3
IUPAC name: 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yl acetate
InChI Identifier: InChI=1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3
InChI Key: ZAKOWWREFLAJOT-UHFFFAOYSA-N
Isomeric SMILES: CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=C(C)C(OC(C)=O)=C(C)C(C)=C2O1
Average Molecular Weight: 472.7428
Monoisotopic Molecular Weight: 472.39164553

IUPAC Name: [(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate
Molecular Weight: 472.74
Molecular Formula: C31H52O3
Canonical SMILES: CC1=C(C(=C(C2=C1OC(CC2)(C)CCCC(C)CCCC(C)CCCC(C)C)C)OC(=O)C)C
InChI: InChI=1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1
InChIKey: ZAKOWWREFLAJOT-CEFNRUSXSA-N
Boiling Point: 224°C0.3mm Hg(lit.)
Melting Point: 28°C
Flash Point: >230 °F
Density: 0.953 g/mL at 25 °C(lit.)
Solubility: Soluble in Chloroform (Slightly), Ethanol (Slightly, Sonicated), Ethyl Acetate (Slightly)
Appearance: Colourless to Light Yellow Thick Oil to Low-Melting Solid
Application: anticoagulant
Storage: -20°C
Assay: 0.9999
EINECS: 200-405-4
MDL: MFCD00072052
Refractive Index: 1.494-1.498
Stability: Stable.



FIRST AID MEASURES of ALPHA-TOCOPHEROL ACETATE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ALPHA-TOCOPHEROL ACETATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ALPHA-TOCOPHEROL ACETATE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ALPHA-TOCOPHEROL ACETATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Respiratory protection:
Not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ALPHA-TOCOPHEROL ACETATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
*Storage stability:
Recommended storage temperature: 2 - 8 °C



STABILITY and REACTIVITY of ALPHA-TOCOPHEROL ACETATE:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available



SYNONYMS:
Vitamin E acetate
alpha-Tocopherol acetate
58-95-7
Tocopherol acetate
Alfacol
Tocopheryl acetate
D-alpha-tocopherol acetate
D-ALPHA-TOCOPHERYL ACETATE
Ecofrol
Contopheron
Tofaxin
Econ
Ephynal acetate
Tokoferol acetate
Evipherol
Fertilvit
Tocopherex
Tocophrin
Erevit
Gevex
(+)-alpha-Tocopherol acetate
Combinal E
Epsilan-M
E-Toplex
E-Ferol
Endo E Dompe
Ephynal
Spondyvit
Juvela
alpha-Tocopheryl acetate
Copherol 1250
Covitol 1100
Covitol 1360
Vitamin Ealpha acetate
Vitamin E acetate, d-
Nanotopes
Simmyungsaengmosu
NatAc
Tinoderm E
Natur-E granulate
DL-alpha-Tocopheryl acetate
Lutavit E 50
(+)-alpha-Tocopheryl acetate
CCRIS 4389
(R,R,R)-alpha-Tocopheryl acetate
C31H52O3
EINECS 200-405-4
UNII-A7E6112E4N
(+-)-alpha-Tocopherol acetate
52225-20-4
D-alpha tocoferil acetate
alpha-Tocopherol acetate, all rac
(2R,4'R,8'R)-alpha-Tocopheryl acetate
A7E6112E4N
DL-alpha-Tocopherylacetate
d-Alpha Tocopheryl Acetate
.alpha.-Tocopherol acetate
alpha-Tocopherol acetate, (2R,4'R,8'R)-
EINECS 231-710-0
MFCD00072052
RRR-alpha-tocopheryl acetate
(+)-alfa-tocopherol acetate
alpha-tocopheryl acetate, D-
D-.alpha.-Tocopherol acetate
Tocopheryl acetate, D-alpha-
Vitamin E Acetate (D-form)
UNII-9E8X80D2L0
Vectan (TN)
BRN 0097512
CCRIS 6054
54-22-8
DTXSID1031096
CHEBI:32321
9E8X80D2L0
D-|A-Tocopherol acetate
Tocopherolacetate, alpha-
DL-alpha tocopheryl acetate
EINECS 257-757-7
MFCD00072042
T-3376
d-Vitamin E acetate
Tocopherol acetate [JAN]
.alpha.-Tocopheryl acetate
Tocopherol acetate (JP17)
Tocopheryl Acetate, d-Alpha
CHEMBL1047
NCGC00166253-02
SCHEMBL22298
2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-cromanyl acetate, (+)-
6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-
6-Cromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate
MLS001335985
MLS001335986
DTXCID601356
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (2R-(2*(4R*,8R*)))-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R*(4R*,8R*)]]-
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl acetate, (2R-(2*(4R*,8R*)))-
DTXSID3021356
(+)-.alpha.-Tocopherol acetate
(+)-.alpha.-Tocopheryl acetate
DL-alpha-Tocopherylacetate (Vitamin E acetate)
EC 231-710-0
Syntopherol acetate
HMS2230C20
5-17-04-00169 (Beilstein Handbook Reference)
Tox21_111491
Tox21_111564
Tox21_113467
Tox21_303444
ALPHA-TOCOPHEROL ACETATE, D-
ALPHA-TOCOPHEROL ACETATE. D-
LS-245
Rovimix E 50SD
(R,R,R)-.alpha.-Tocopheryl acetate
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
AKOS025117621
NSC 755840
NSC-755840
Tox21_113467_1
[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate
1406-70-8
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, acetate, (2R)-
.ALPHA.-TOCOPHEROL ACETATE, D-
CAS-58-95-7
NCGC00095255-08
NCGC00166253-01
NCGC00257504-01
DL--Tocopherol acetate
AS-13784
J24.807J
LS-39402
LS-53371
SMR000857327
CAS-52225-20-4
O-Acetyl-alpha-tocopherol
(2R,4'R,8'R)-.alpha.-Tocopheryl acetate
DL-alpha-Tocopherol acetate, >=96% (HPLC)
Vitamin E acetate dl-form
6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate
C13202
D01735
DL-alpha-Tocopherol acetate, analytical standard
[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-yl] acetate
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-b- enzopyran-6-ol, acetate
d,l-alpha-Tocopheryl acetate
Eusovit
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, 6-acetate, (2R)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, acetate, (2R)-rel-
D-.alpha.-Tocopheryl acetate
Alpha-tocopherol acetate, dl-
Q-201933
vitamin E acetate, (2R-(2R*(4R*,8R*)))-isomer
W-109259
ECA8C22F-B5D3-4B88-A9B7-AF6C600001BB
vitamin E acetate, ((2R*(4R*,8R*))-(+-))-isomer
DL-alpha-Tocopherol acetate, tested according to Ph.Eur.
DTXCID60196594
OptoVit E
SynAC
Rovimix E 50
Alpha Tocopheryl Acetate, United States Pharmacopeia (USP) Reference Standard
alpha-Tocopherol acetate, European Pharmacopoeia (EP) Reference Standard
DL-alpha-Tocopherol acetate, certified reference material, TraceCERT(R)
DL-alpha-Tocopherylacetate (Vitamin E acetate) 10 microg/mL in Acetonitrile
(+)-alpha-Tocopherol acetate, BioReagent, suitable for insect cell culture, ~1360 IU/g
(R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl acetate
2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-yl acetate #
Tocopheryl Acetate, a, Pharmaceutical Secondary Standard; Certified Reference Material
(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl acetate
(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-yl acetate
(2R*(4R*,8R*))-(1)-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
[2R-[2R*(4R,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol acetate
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, 6-acetate
2H-1-benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate,
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (2R-(2R*(4R*,8R*)))-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate,(2R*(4R*,8R*))-(+-)-
All-rac-alpha-tocopheryl acetate for peak identification, European Pharmacopoeia (EP) Reference Standard
Tocopheryl acetate,alpha
Alpha Tocopheryl Acetate
D-ALPHA TOCOFERIL ACETATE (MART.)
D-ALPHA TOCOFERIL ACETATE [MART.]
UNII-WR1WPI7EW8
Copherol 12250
d-|ATocopheryl Acetate
O-Acetyl-|A-tocopherol
alpha-Tocopherylis acetas
AC1L3BMH
DL-|A-Tocopheryl acetate
.alpha.-tocopherol acetate, dl-
AC1Q1PB2
(+)-|A-Tocopherol acetate
(+)-|A-Tocopheryl Acetate
all-rac-|A-Tocopheryl acetate
DL-ALPHA-TOCOPHEROLACETATE
C31-H52-O3
(R,R,R)-|A-Tocopheryl Acetate
(2R,4'R,8'R)-alpha-Tocopherol acetate
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, acetate, (2R)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, acetate, (2R)-rel-
Tocopherol, acetate
Acetate, Tocopherol
ZINC4172337
alpha-tocopherylacetat
FT-0624407
a- tocopheryl acetate
D--Tocopherol acetate
(2R,4'R,8'R)-|A-Tocopherol Acetate
(2R,4'R,8'R)-|A-Tocopheryl Acetate
SC-16401
SC-18242
alpha Tocopherol Acetate
DSSTox_CID_1356
d alpha Tocopheryl Acetate
DL-alpha-Tocopherol acetate, 50% powder form
J10308
DL-alpha-Tocopherol acetate, EP/USP/FCC grade
DSSTox_RID_76104
DSSTox_RID_78863
DSSTox_GSID_21356
DSSTox_GSID_31096
Vitamin E acetate (unlabeled)
VITAMIN E ALPHA ACETATE
(+)- alpha -Tocopherol acetate
TOCOPHERYL ACETATE,D-ALPHA
D-alpha-Tocopheryl acetate, 97%
MolPort-003-928-528
DL-alpha-Tocopheryl acetate, 98%
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl- 2-(4,8,12-trimethyltridecyl)-, acetate
3, 4- dihydro- 2, 5, 7, 8- tetramethyl- 2- (4, 8, 12- trimethyltridecyl)- 2H- benzopyran- 6- yl acetate
HY-B1278
TOCOPHERYL ACETATE [WHO-DD]
Vitamin E acetate, unspecified form
TOCOPHERYL ACETATE, alpha, D-
s3681
Vitamin E (alpha tocopherol acetate)
2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol acetate
CCG-269474
CS-O-00415
DB14002
.ALPHA.-TOCOPHEROL ACETATE. D-
(+-)-alpha-Tocopherol Acetateacid ester
.ALPHA.-TOCOPHEROL ACETATE [MI]
TOCOPHERYL ACETATE, .ALPHA., D-
(2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol 6-Acetate
[2R*(4R*,8R*)]-()-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
133-80-2
2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-,6-acetate, (2R)-
AK176402
all-rac-2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yl acetate
ALPHA TOCOPHERYL ACETATE (USP-RS)
RRR-ALPHA-TOCOPHERYL ACETATE [FCC]
TOCOPHERYL ACETATE,D-ALPHA [VANDF]
CS-0013056
T2322
VITAMIN E (ALPHA-TOCOPHERYL ACETATE)
A11606
D70796
alpha-TOCOPHEROL ACETATE, UNSPECIFIED FORM
EN300-7398027
A865381
Q364160
Z2681891483
UNII-WR1WPI7EW8 component ZAKOWWREFLAJOT-CEFNRUSXSA-N
Vitamin E acetate (dimethyl-13C2, acetyl-13C2, 99%; dimethyl-D6, 98%)
(+)-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECYL)-6-CHROMANOL ACETATE
(2R-(2R*(4R*,8R*)))-3,4-DIHYDRO-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRI-DECYL)-2H-1-BENZOPYRAN-6-OL ACETATE
[2R*(4R*,8R*)]-(+-)-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
12741-00-3
1407-18-7
26243-95-8
2H-1-Benzopiran-6-ol, 3,4-dihidro-2,5,7,8-tetrametil-2-[(4R,8R)-4,8,12-trimetiltridecil]-, 6-acetato, (2R)-rel-
2H-1-benzopirano-6-ol, 3,4-dihidro-2,5,7,8-tetrametil-2-[(4R, 8R)-4,8,12-trimetiltridecil]-, 6-acetato, ( 2R)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl- 2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R(4R,8R)]]-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R*(4R*,8R*)]-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R*(4R*,8R*)]-(.+.)-
2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-,acetate, (2R)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R*(4R*,8R*)]]-
Vitamin E acetate; 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-
α-Tocopherol acetate
(+)-α-Tocopherol acetate
(+)-α-Tocopheryl acetate
D-α-tocopherol acetate
D-α-tocopheryl acetate
Alfacol
Combinal E
Contopheron
E-Ferol
E-Toplex
Ecofrol
Econ
Endo E Dompe
Ephynal acetate
Epsilan-M
Erevit
Evipherol
Fertilvit
Gevex
Juvela
Tocopherex
Tocophrin
Tofaxin
Tokoferol acetate
[2R-[2R*(4R,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol acetate
d-Vitamin E acetate
E-vicotrat
Spondyvit
(2R,4'R,8'R)-α-Tocopheryl acetate
(R,R,R)-α-Tocopheryl acetate
Copherol 1250
Covitol 1100
Covitol 1360
Tocopheryl acetate
Vitamin Ealpha acetate
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate
Vitamin E acetate
dl-α-Tocopheryl acetate
(+)-.alpha.-Tocopherol, O-acetyl-
(+)-α-Tocopherol acetate
2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-yl acetate
3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
(+)-alpha -Tocopherol acetate
(+)-alpha -Tocopheryl acetate
(+)-alpha-Tocopherol acetate
(+)-alpha-tocopherol acetate
(+)-alpha-Tocopheryl acetate
(+)-alpha-tocopheryl acetate
(+)-α-tocopherol acetate
(+)-α-tocopheryl acetate
(+-)-alpha-Tocopherol acetate
(+-)-alpha-tocopherol acetate
a-Tocopherol acetate
a-Tocopherol acetic acid
alpha-Tocopherol acetic acid
Α-tocopherol acetate
Α-tocopherol acetic acid
(+)-alpha -Tocopherol acetate
(+)-alpha -Tocopheryl acetate
(+)-alpha-Tocopherol acetate
(+)-alpha-Tocopheryl acetate
(+-)-alpha-Tocopherol acetate
(2R,4'r,8'r)-alpha-Tocopherol acetate
(2R,4'r,8'r)-alpha-Tocopheryl acetate
(R,R,R)-alpha-Tocopheryl acetate
Alfacol
all-rac-alpha-Tocopheryl acetate
alpha -Tocopherol acetate
alpha -Tocopheryl acetate
alpha-Tocopherol acetate, all rac
alpha-Tocopheryl acetate
Combinal e
Contopheron
Copherol 1250
Covitol 1100
Covitol 1360
D,L-alpha-Tocopheryl acetate
D-alpha -Tocopherol acetate
D-alpha -Tocopheryl acetate
D-alpha-Tocopherol acetate
D-alpha-Tocopheryl acetate
D-Vitamin e acetate
DL-alpha Tocopheryl acetate
DL-alpha-Tocopherol acetate
DL-alpha-Tocopheryl acetate
e-Ferol
e-Toplex
e-Vicotrat
Ecofrol
ECON
endo e Dompe
Ephynal acetate
Epsilan-m
Erevit
Fertilvit
Gevex
Juvela
O-Acetyl-alpha-tocopherol
Rovimix e 50Sd
Spondyvit
Syntopherol acetate
Tocopherex
Tocopherol acetate
Tocopherol acetate (JP15)
Tocopheryl acetate
Tocophrin
Tofaxin
Tokoferol acetate
Vectan
Vitamin e acetate
Vitamin e acetate DL-form
Vitamin e acetate, ((2R*(4R*,8R*))-(+-))-isomer
Vitamin e acetate, (2R-(2R*(4R*,8R*)))-isomer
Vitamin ealpha acetate
2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yl acetic acid
Tocopherol succinate
alpha Tocopherol succinate
Acetate, tocopherol
Calcium succinate, alpha-tocopheryl
R,R,R-alpha-Tocopherol
alpha Tocopheryl calcium succinate
alpha-Tocopherol
alpha-Tocopherol acetate
alpha-Tocopherol hemisuccinate
D alpha Tocopherol
D alpha Tocopheryl acetate
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol
Succinate, tocopherol
alpha Tocopherol hemisuccinate
Tocopherol, D-alpha
alpha Tocopherol
alpha Tocopherol acetate
alpha-Tocopheryl calcium succinate
alpha-Tocopherol succinate
D-alpha Tocopherol
(2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol 6-Acetate
Ephynal Acetate
(+)-α-Tocopherol Acetate
(+)-α-Tocopheryl Acetate
(2R,4'R,8'R)-α-Tocopherol Acetate
(2R,4'R,8'R)-α-Tocopheryl Acetate
(R,R,R)-α-Tocopheryl Acetate
2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol Acetate
Alfacol
Copherol 12250
Ecofrol
Econ
Tofaxin
Tokoferol Acetate
all-rac-alpha-Tocopheryl Acetate
DL-alpha-Tocoferil Acetate
(+/-)-alpha-Tocopherol Acetate
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, 6-acetate, (2R)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, acetate, (2R)-
alpha-Tocopheryl acetate
Tocopheryl acetate, D-alpha-
Vitamin E acetate
(+)-alpha-Tocopherol acetate
(+)-alpha-Tocopheryl acetate
(2R,4'R,8'R)-alpha-Tocopheryl acetate
(R,R,R)-alpha-Tocopheryl acetate
2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-cromanyl acetate, (+)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (2R-(2*(4R*,8R*)))-
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl acetate, (2R-(2*(4R*,8R*)))-
6-Cromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-
Alfacol
alpha-Tocopherol acetate, (2R,4'R,8'R)-
Combinal E
Contopheron
Copherol 1250
Covitol 1100
Covitol 1360
d-alpha-Tocopherol acetate
D-alpha-Tocopheryl acetate
d-alpha-Tocopheryl acetate
E-Ferol
E-Toplex
Ecofrol
Econ
Endo E Dompe
Ephynal acetate
Epsilan-M
Erevit
Evipherol
Fertilvit
Gevex
Juvela
Simmyungsaengmosu
Tocopherex
Tocopheryl acetate
Tocophrin
Tofaxin
Tokoferol acetate
Vitamin E acetate, d-
Vitamin Ealpha acetate
Spondyvit



ALS (AMMONIUM LAURYL SULFATE)
Ammonium Lauryl Sulfate (ALS) Ammonium lauryl sulfate (ALS) is the common name for ammonium dodecyl sulfate (CH3(CH2)10CH2OSO3NH4). The anion consists of a nonpolar hydrocarbon chain and a polar sulfate end group. The combination of nonpolar and polar groups confers surfactant properties to the anion: it facilitates dissolution of both polar and non-polar materials. Ammonium lauryl sulfate (ALS) is classified as a sulfate ester. Ammonium lauryl sulfate (ALS) is found primarily in shampoos and body-wash as a foaming agent.[1]/[2] Ammonium lauryl sulfate (ALS) are very high-foam surfactants that disrupt the surface tension of water in part by forming micelles at the surface-air interface. Contents 1 Action in solution of Ammonium lauryl sulfate (ALS) 2 Safety of Ammonium lauryl sulfate (ALS) 3 Occupational exposure of Ammonium lauryl sulfate (ALS) 4 Environment Action in solution Above the critical micelle concentration, the anions organize into a micelle, in which they form a sphere with the polar, hydrophilic heads of the sulfate portion on the outside (surface) of the sphere and the nonpolar, hydrophobic tails pointing inwards towards the center. The water molecules around the micelle in turn arrange themselves around the polar heads, which disrupts their ability to hydrogen bond with other nearby water molecules. The overall effect of these micelles is a reduction in surface tension of the solution, which affords a greater ability to penetrate or "wet out" various surfaces, including porous structures like cloth, fibers, and hair. Accordingly, this structured solution allows the solution to more readily dissolve soils, greases, etc. in and on such substrates. Ammonium lauryl sulfate (ALS) however exhibit poor soil suspending capacity.[2] Safety of Ammonium lauryl sulfate (ALS) Ammonium lauryl sulfate (ALS) is an innocuous detergent. A 1983 report by the Cosmetic Ingredient Review, shampoos containing up to 31% Ammonium lauryl sulfate (ALS) registered 6 health complaints out of 6.8 million units sold. These complaints included two of scalp itch, two allergic reactions, one hair damage and one complaint of eye irritation. The CIR report concluded that both sodium and Ammonium lauryl sulfate (ALS) “appear to be safe in formulations designed for discontinuous, brief use followed by thorough rinsing from the surface of the skin. In products intended for prolonged use, concentrations should not exceed 1%.” The Human and Environmental Risk Assessment (HERA) project performed a thorough investigation of all alkyl sulfates, as such the results they found apply directly to Ammonium lauryl sulfate (ALS). Most alkyl sulfates exhibit low acute oral toxicity, no toxicity through exposure to the skin, concentration dependent skin irritation, and concentration dependent eye-irritation. They do not sensitize the skin and did not appear to be carcinogenic in a two-year study on rats. The report found that longer carbon chains (16–18) were less irritating to the skin than chains of 12–15 carbons in length. In addition, concentrations below 1% were essentially non-irritating while concentrations greater than 10% produced moderate to strong irritation of the skin.[5] Occupational exposure The CDC has reported on occupations which were routinely exposed to Ammonium lauryl sulfate (ALS) between 1981 and 1983. During this time, the occupation with the highest number of workers exposed was registered nurses, followed closely by funeral directors.[6] Environment The HERA project also conducted an environmental review of alkyl sulfates that found all alkyl sulfates are readily biodegradable and standard wastewater treatment operations removed 96–99.96% of short-chain (12–14 carbons) alkyl sulfates. Even in anaerobic conditions at least 80% of the original volume is biodegraded after 15 days with 90% degradation after 4 weeks. We've put together some information about Ammonium lauryl sulfate (ALS) and SLS which will hopefully be useful for you. We get a lot of questions about sodium lauryl sulphate (SLS) and Ammonium lauryl sulfate (ALS). We would like to reassure you that our safe, natural shampoos are all Ammonium lauryl sulfate (ALS)-free and SLS-free. We've put together some information about Ammonium lauryl sulfate (ALS) and SLS which will hopefully be useful for you. WHAT MAKES SLS IRRITATING? Although sodium lauryl sulphate (SLS) and Ammonium lauryl sulfate (ALS) have similar sounding names and are both classed as anionic surfactants, they have different molecular structures. SLS is a comparatively simple molecule and is therefore quite small in size. This gives it the ability to penetrate the outer layers of the skin, particularly when used in conditions which encourage the skin's pores to open, such as when in a warm bath or shower. When SLS penetrates the outer layers of the skin in this way, it comes into contact with more delicate cells that are in the process of being formed in the dermis. Ammonium lauryl sulfate (ALS) is here that the irritation associated with SLS manifests itself, resulting in reddening and erythema of the skin. A is an anionic surfactant from the group of alkyl sulphates, INCI name: Ammonium lauryl sulfate (ALS). Ammonium lauryl sulfate (ALS) is mainly intended for personal care products. It has the form of a clear, viscous liquid in colour from colourless to light yellow. The active substance content in the commercial product is around 27%. The microbiological purity of the product is ensured by the addition of sodium benzoate. The main advantage of the product is the preservation of washing and foaming properties even in the presence of excessive amounts of sebum. ROSULfan A has a much higher resistance to hard water and, at the same time, has a much lower irritating and drying effect compared to Sodium Lauryl Sulfate. In compositions containing Sodium Lauryl Sulfate and / or Sodium Laureth Sulfate, the use of ROSULfAN A reduces the irritant effect of these surfactants. This is especially important in delicate shampoos recommended for sensitive skin. The product is completely biodegradable and meets the criteria of cosmetics and detergent directives. It also has the Ecocert COSMOS certificate for cosmetic ingredients. In the construction industry, it is used as an ingredient in agents reducing the weight of drywall, as well as air-entraining and plasticizing admixtures. However, in emulsion polymerization, ROSULfan A provides excellent stabilization of the polymer dispersion at lower pH ranges. Thanks to its use, it is possible to control the particle size, including acrylic, styrene-acrylic systems, vinyl acetate homo- and copolymers, VaE type dispersions and PVC emulsion. What Is Ammonium lauryl sulfate (ALS)? Sodium lauryl sulfate and Ammonium lauryl sulfate (ALS) are widely used surfactant in shampoos, bath products, hair colorings, facial makeup, deodorants, perfumes, and shaving preparations; however, they can also be found in other product formulations. Why is it used in cosmetics and personal care products? Sodium lauryl sulfate and Ammonium lauryl sulfate (ALS) are surfactant that help with the mixing of oil and water. As such, they can clean the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away or suspend poorly soluble ingredients in water. Safety Information: The U.S. Food and Drug Administration (FDA) includes sodium lauryl sulfate on its list of multipurpose additives allowed to be directly added to food. Sodium lauryl sulfate and Ammonium lauryl sulfate (ALS) are also approved indirect food additives. For example, both ingredients are permitted to be used as components of coatings. The safety of sodium lauryl sulfate and Ammonium lauryl sulfate (ALS) has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel on two separate occasions (1983 and 2002), concluding each time that the data showed these ingredients were safe in formulations designed for brief, discontinuous use, followed by thorough rinsing from the surface of the skin. In products intended for prolonged contact with skin, concentrations should not exceed 1%. More safety Information: Sodium lauryl sulfate and Ammonium lauryl sulfate (ALS) may be used in cosmetics and personal care products marketed in Europe according to the general provisions of the Cosmetics Regulation of the European Union . Is there any truth to the Internet rumors about sodium lauryl sulfate? Since 1998, a story has been circulating on the Internet that states that sodium lauryl sulfate can cause cancer. This allegation is unsubstantiated and false. In fact, in a 2002 safety review, the CIR Expert Panel assessed all of the data on sodium lauryl sulfate and concluded that “[n]one of the data suggested any possibility that sodium lauryl sulfate or Ammonium lauryl sulfate (ALS) could be carcinogenic. Despite suggestions to the contrary on the Internet, the carcinogenicity of these ingredients is only a rumor.” Ammonium lauryl sulfate (ALS) & Your Hair: Ingredients and Advice We often buy shampoo without really knowing what’s in it. We may have been seduced into said purchase because of an attractive price, an online ad or a recommendation from a friend. Or – and let’s be honest here – simply because we liked the design and colour of the bottle. It can be very disappointing to discover that, after a few times of using it, our hair does not feel its usual, silky self. We notice a crispiness, lesser defined curls, perhaps even damage. Naturally, this will get us thinking about our choice of shampoo and whether it’s really the right fit for our hair or not. Upon studying the ingredients listed on the bottle and trying to figure out how beneficial or harmful they can be to our curly hair, we are faced with many terms we are completely unfamiliar with. Among them, we have several types of sulfates, the different types of which can be just as difficult to identify. One of these sulfates is the Ammonium lauryl sulfate (ALS). You have probably used several products containing this sulfate; it is common in all types of beauty and cosmetic goods including shampoos, but also toothpaste, body gels and soaps. It is a widely used ingredient in these kinds of products, not only because of its cleansing properties but also because it is very economical. There is a lot of speculation about this particular sulfate and its effects on our hair, with many sources advocating for its use and many others warning us against it. In this article, we’ll get to the bottom of this common shampoo ingredient and its characteristics. What is Ammonium lauryl sulfate (ALS)? Ammonium lauryl sulfate (ALS) is an ammonium salt. Although it is originally derived from the coconut, it is commonly created in laboratories for its use in all types of products. As is true for every other sulfate, Ammonium lauryl sulfate (ALS) is a surfactant (“Surface active agent”) – that is, an active agent that creates tension between two surfaces. In the case of a shampoo, Ammonium lauryl sulfate (ALS) is used to create foam once it comes into contact with water. This foam helps to wash away grease and dirt in general, as well as to maximize the cleaning efficiency of the product. It also has a psychological, commercial component to it, as many users believe that, the more foam a product generates, the more cleansing it is. Ammonium lauryl sulfate (ALS) is an improved form of Ammonium lauryl sulfate (ALS). The suffix, “eth”, comes from the added oxygen through a process known as ethoxylation, which makes this agent softer and more water-soluble. This addition has proven to be a solution against sulfate residues that persist in the skin after washing your hair, and provides a milder, less aggressive agent. Is Ammonium lauryl sulfate (ALS) Safe to Use on Your Hair? The problem with sulfates and the foam they create is that they do their job too well. A sulfate basically acts as a detergent that eliminates dirt when we apply it, but also our hair’s natural oils. As such, it can eliminate our hair’s natural protection. This becomes a problem when using a shampoo with Ammonium lauryl sulfate (ALS) on a regular basis. In this case, we are not leaving these natural oils enough time to form again. When used sporadically, this sulfate is considered to be gentle on our hair and skin. If used excessively, though, Ammonium lauryl sulfate (ALS) – and all sulfates in general – dry out our hair, to the point of causing skin irritations and even the apparition of dandruff. It also makes our hair that much more brittle. In the long term, it may not only affect our hair’s health but its colour, too. In the most extreme cases (and, generally, mostly among men), it can lead to hair loss. HOW IS Ammonium lauryl sulfate (ALS) DIFFERENT? Ammonium lauryl sulfate (ALS), by contrast, is a slightly more complex molecule and is physically larger with a heavier molecular mass. This means that it is more difficult for Ammonium lauryl sulfate (ALS) molecules to penetrate the outer layers of the skin and so reach the delicate underlying layers of cells. Due to this difference, Ammonium lauryl sulfate (ALS) is regarded as being considerably less irritating than SLS – on a scale of 0 to 10, where the potential irritancy of water is 0 and that of SLS is 10, Ammonium lauryl sulfate (ALS) scores around 4 – clearly far less irritating than SLS. SLS AND Ammonium lauryl sulfate (ALS)-FREE SHAMPOOS We do not use Ammonium lauryl sulfate (ALS) or SLS in our hair care products. All of our organic shampoos use different surfactants which are kind to skin. Full ingredients lists are available on each product page. What is Ammonium lauryl sulfate (ALS) and SLS, and what is the difference between them? Are you the type of person that looks and questions every ingredient in the products you purchase? Don’t worry, that’s a good thing! We’re happy to know people care about what they are in contact with, and we’ve definitely gotten a few questions about our ingredients as well. Which is why we’re here to give you the low down on our Lunette Feelbetter Cup Cleanser and the surfactant we use in it — Ammonium lauryl sulfate (ALS) (ASL), and compare it the one we don’t use, Sodium Lauryl Sulfate (SLS). Try not to get tongue twisted ;) What is Ammonium lauryl sulfate (ALS) and SLS, and what is the difference between them? Ammonium lauryl sulfate (ALS) and Sodium Lauryl Sulfate are both anionic surfactants. English, please? A surfactant is a compound that decreases the surface tension between two liquids, a solid or a liquid, or a gas and a liquid. They often act as detergents, foaming agents, and more by helping to mix water with oil and dirt so they can be washed away. Science rules. ASL and SLS have similar-sounding names but what makes them different is their molecular structure. Are Ammonium lauryl sulfate (ALS) and SLS safe to use? For decades, sulphates have been in the focus of critical parties, even though they are an incredibly efficient fat remover and create a ton of foam. They are considered as environmentally friendly, as they are very quickly biodegradable and won’t typically cause any allergies. Sulfates are recognized among others by the Asthma and Allergy Society in all countries and therefore widely used in most shampoos, sanitary cleansing gels, dishwashers, etc., to dissolve fat the most effectively. Although there have been reports that SLS is carcinogenic, there is no scientifically proven link to it. Many reports on the Internet cannot verify this argument with convincing scientific evidence. In fact, cosmetic products in the European Union must comply with strict guidelines and prove their safety before they can be sold. The flip side of why someone would be against these surfactants is that, because of their efficacy in high concentrations, they are particularly irritating to the eyes and skin. This is being emphasized again and again by most opponents. News flash — all surfactants used are usually harmful to the eyes, whether they are SLS, Ammonium lauryl sulfate (ALS) or other compounds. However, Ammonium lauryl sulfate (ALS) has been found clearly milder than sodium lauryl sulfate in irritation tests In an article of the "Cosmetic Ingredients Review", only six complaints were reported for shampoos containing up to 31% Ammonium lauryl sulfate (ALS) with 6.8 million units sold. The Cosmetic Ingredient Review report also states, that "Sodium Lauryl Sulfate and Ammonium lauryl sulfate (ALS) appear to be safe in formulations designed for discontinuous, brief use followed by thorough rinsing from the surface of the skin.” Usually, you only come in contact with surfactants for a short amount of time, like when you’re washing your hair or cleaning your menstrual cup. In this short contact, which is then rinsed with water, the risk of irritation is very low. Why aren’t we using “soft” surfactants? A current trend is to use ingredients that are made by marketing campaigns to sound "soft and gentle" and "used earlier". Therefore, in natural cosmetics, for example, glucosides are used, such as Coco Glucosides, Lauryl Glucosides, Decyl Glucosides, since glucosides have a glucose, i.e. a sugar base. Glucosides are much weaker in foam than sulfates, and they are not as easily thickened as sulfates. You then need polymers or gums as thickeners. However, polymers are banned in natural cosmetics and substances that are permitted in natural cosmetics, such as xanthan gum, cause the gel to leave a sticky feeling on the skin. Other alternatives, than glucosides, are weaker in foam than sulfates and harder to thicken. Therefore, cleaners containing sulfates, on the other hand, can easily be thickened to gel without the need to use thickening polymers or gums which, can easily leave a sticky feeling. You don’t want a sticky cup, right? ;) In order to clean the Lunette Menstrual Cups thoroughly, we have chosen Ammonium lauryl sulfate (ALS) for its effectiveness as one of the ingredients in our Feelbetter Cup Cleanser. Ammonium lauryl sulfate (ALS) leaves no residue on the surface of the cup, and Ammonium lauryl sulfate (ALS) is recognized by the "Allergy, Skin and Asthma Federation" as an ingredient in cosmetic products. Many people still confuse Ammonium lauryl sulfate (ALS) with the "infamous" Sodium Lauryl Sulfate (SLS). The second surfactant we use is called cocamidopropyl betaine. This surfactant is preferred in natural cosmetics, but Ammonium lauryl sulfate (ALS) does not work well enough alone, so we paired it with the more effective Ammonium lauryl sulfate (ALS). If this little science lesson has got you curious about our Lunette Feelbetter Cup Cleanser, you can buy one on our website! Ammonium lauryl sulfate (ALS) doesn’t contain any artificial fragrances — instead, it’s scented with lemon and eucalyptus oil, selected for their purifying and cleansing properties! Ammonium lauryl sulfate (ALS) Usage And Synthesis Chemical Properties yellow viscous liquid Uses Ammonium lauryl sulfate (ALS) is a surfactant with emulsifying capabilities. given its detergent properties, at mild acidic pH levels it can be used as an anionic surfactant cleanser. Ammonium lauryl sulfate (ALS) is considered one of the most irritating surfactants, causing dryness and skin redness. Today, it is either combined with anti-irritant ingredients to reduce sensitivity or replaced with a less irritating but similar surfactant, such as Ammonium lauryl sulfate (ALS). General Description Light yellow liquid. May float or sink and mix with water. Air & Water Reactions Water soluble. Reactivity Profile Acidic inorganic salts, such as Ammonium lauryl sulfate (ALS), are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. Health Hazard Contact with liquid irritates eyes and may have drying effect on the skin. Prolonged contact will cause skin irritation. Fire Hazard Special Hazards of Combustion Products: Toxic oxides of nitrogen and sulfur may form in fires. A is an anionic surfactant from the group of alkyl sulphates, INCI name: Ammonium lauryl sulfate (ALS). Ammonium lauryl sulfate (ALS) is mainly intended for personal care products. It has the form of a clear, viscous liquid in colour from colourless to light yellow. The active substance content in the commercial product is around 27%. The microbiological purity of the product is ensured by the addition of sodium benzoate. The product has the ability to produce dense and stable foam, which allows fine and evenly distributed air bubbles to be obtained. Due to these properties, ROSULfan A is used as the main ingredient in cleansing cosmetic products. Ammonium lauryl sulfate (ALS) is dedicated to shampoos, body wash and shower gels. The main advantage of the product is the preservation of washing and foaming properties even in the presence of excessive amounts of sebum. ROSULfan A has a much higher resistance to hard water and, at the same time, has a much lower irritating and drying effect compared to Sodium Lauryl Sulfate. In compositions containing Sodium Lauryl Sulfate and / or Sodium Laureth Sulfate, the use of ROSULfAN A reduces the irritant effect of these surfactants. This is especially important in delicate shampoos recommended for sensitive skin. The product is completely biodegradable and meets the criteria of cosmetics and detergent directives. It also has the Ecocert COSMOS certificate for cosmetic ingredients. In the construction industry, it is used as an ingredient in agents reducing the weight of drywall, as well as air-entraining and plasticizing admixtures. However, in emulsion polymerization, ROSULfan A provides excellent stabilization of the polymer dispersion at lower pH ranges. Thanks to its use, it is possible to control the particle size, including acrylic, styrene-acrylic systems, vinyl acetate homo- and copolymers, VaE type dispersions and PVC emulsion. What Is Ammonium lauryl sulfate (ALS)? Sodium lauryl sulfate and Ammonium lauryl sulfate (ALS) are widely used surfactant in shampoos, bath products, hair colorings, facial makeup, deodorants, perfumes, and shaving preparations; however, they can also be found in other product formulations. Why is it used in cosmetics and personal care products? Sodium lauryl sulfate and Ammonium lauryl sulfate (ALS) are surfactant that help with the mixing of oil and water. As such, they can clean the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away or suspend poorly soluble ingredients in water. Safety Information: The U.S. Food and Drug Administration (FDA) includes sodium lauryl sulfate on its list of multipurpose additives allowed to be directly added to food. Sodium lauryl sulfate and Ammonium lauryl sulfate (ALS) are also approved indirect food additives. For example, both ingredients are permitted to be used as components of coatings. The safety of sodium lauryl sulfate and Ammonium lauryl sulfate (ALS) has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel on two separate occasions (1983 and 2002), concluding each time that the data showed these ingredients were safe in formulations designed for brief, discontinuous use, followed by thorough rinsing from the surface of the skin. In products intended for prolonged contact with skin, concentrations should not exceed 1%. This addition has proven to be a solution against sulfate residues that persist in the skin after washing your hair, and provides a milder, less aggressive agent. Is Ammonium lauryl sulfate (ALS) Safe to Use on Your Hair? The problem with sulfates and the foam they create is that they do their job too well. A sulfate basically acts as a detergent that eliminates dirt when we apply it, but also our hair’s natural oils. As such, it can eliminate our hair’s natural protection. This becomes a problem when using a shampoo with Ammonium lauryl sulfate (ALS) on a regular basis. In this case, we are not leaving these natural oils enough time to form again. When used sporadically, this sulfate is considered to be gentle on our hair and skin. If used excessively, though, Ammonium lauryl sulfate (ALS) – and all sulfates in general – dry out our hair, to the point of causing skin irritations and even the apparition of dandruff. Ammonium lauryl sulfate (ALS) is the common name for ammonium dodecyl sulfate (CH3(CH2)10CH2OSO3NH4). The anion consists of a nonpolar hydrocarbon chain and a polar sulfate end group. The combination of nonpolar and polar groups confers surfactant properties to the anion: it facilitates dissolution of both polar and non-polar materials. Ammonium lauryl sulfate (ALS) is classified as a sulfate ester. Ammonium lauryl sulfate (ALS) is found primarily in shampoos and body-wash as a foaming agent.[1]/[2] Ammonium lauryl sulfate (ALS) are very high-foam surfactants that disrupt the surface tension of water in part by forming micelles at the surface-air interface. Environment The HERA project also conducted an environmental review of alkyl sulfates that found all alkyl sulfates are readily biodegradable and standard wastewater treatment operations removed 96–99.96% of short-chain (12–14 carbons) alkyl sulfates. Even in anaerobic conditions at least 80% of the original volume is biodegraded after 15 days with 90% degradation after 4 weeks. We've put together some information about Ammonium lauryl sulfate (ALS) and SLS which will hopefully be useful for you. We get a lot of questions about sodium lauryl sulphate (SLS) and Ammonium lauryl sulfate (ALS). We would like to reassure you that our safe, natural shampoos are all Ammonium lauryl sulfate (ALS)-free and SLS-free. We've put together some information about Ammonium lauryl sulfate (ALS) and SLS which will hopefully be useful for you. WHAT MAKES SLS IRRITATING? Although sodium lauryl sulphate (SLS) and Ammonium lauryl sulfate (ALS) have similar sounding names and are both classed as anionic surfactants, they have different molecular structures. SLS is a comparatively simple molecule and is therefore quite small in size. This gives it the ability to penetrate the outer layers of the skin, particularly when used in conditions which encourage the skin's pores to open, such as when in a warm bath or shower. When SLS penetrates the outer layers of the skin in this way, it comes into contact with more delicate cells that are in the process of being formed in the dermis. Ammonium lauryl sulfate (ALS) is here that the irritation associated with SLS manifests itself, resulting in reddening and erythema of the skin. HOW IS Ammonium lauryl sulfate (ALS) DIFFERENT? Ammonium lauryl sulfate (ALS), by contrast, is a slightly more complex molecule and is physically larger with a heavier molecular mass. This means that it is more difficult for Ammonium lauryl sulfate (ALS) molecules to penetrate the outer layers of the skin and so reach the delicate underlying layers of cells. We do not use Ammonium lauryl sulfate (ALS) or SLS in our hair care products. All of our organic shampoos use different surfactants which are kind to skin. Full ingredients lists are available on each product page. What is Ammonium lauryl sulfate (ALS) and SLS, and what is the difference between them? Are you the type of person that looks and questions every ingredient in the products you purchase? Don’t worry, that’s a good thing! We’re happy to know people care about what they are in contact with, and we’ve definitely gotten a few questions about our ingredients as well. Which is why we’re here to give you the low down on our Lunette Feelbetter Cup Cleanser and the surfactant we use in it — Ammonium lauryl sulfate (ALS) (ASL), and compare it the one we don’t use, Sodium Lauryl Sulfate (SLS). Try not to get tongue twisted ;) What is Ammonium lauryl sulfate (ALS) and SLS, and what is the difference between them? Ammonium lauryl sulfate (ALS) and Sodium Lauryl Sulfate are both anionic surfactants. English, please? A surfactant is a compound that decreases the surface tension between two liquids, a solid or a liquid, or a gas and a liquid. They often act as detergents, foaming agents, and more by helping to mix water with oil and dirt so they can be washed away. Science rules. ASL and SLS have similar-sounding names but what makes them different is their molecular structure. Are Ammonium lauryl sulfate (ALS) and SLS safe to use? For decades, sulphates have been in the focus of critical parties, even though they are an incredibly efficient fat remover and create a ton of foam. They are considered as environmentally friendly, as they are very quickly biodegradable and won’t typically cause any allergies. Sulfates are recognized among others by the Asthma and Allergy Society in all countries and therefore widely used in most shampoos, sanitary cleansing gels, dishwashers, etc., to dissolve fat the most effectively. Although there have been reports that SLS is carcinogenic, there is no scientifically proven link to it. Many reports on the Internet cannot verify this argument with convincing scientific evidence. In fact, cosmetic products in the European Union must comply with strict guidelines and prove their safety before they can be sold. The flip side of why someone would be against these surfactants is that, because of their efficacy in high concentrations, they are particularly irritating to the eyes and skin. This is being emphasized again and again by most opponents. News flash — all surfactants used are usually harmful to the eyes, whether they are SLS, Ammonium lauryl sulfate (ALS) or other compounds. However, Ammonium lauryl sulfate (ALS) has been found clearly milder than sodium lauryl sulfate in irritation tests In an article of the "Cosmetic Ingredients Review", only six complaints were reported for shampoos containing up to 31% Ammonium lauryl sulfate (ALS) with 6.8 million units sold. The Cosmetic Ingredient Review report also states, that "Sodium Lauryl Sulfate and Ammonium lauryl sulfate (ALS) appear to be safe in formulations designed for discontinuous, brief use followed by thorough rinsing from the surface of the skin.” Usually, you only come in contact with surfactants for a short amount of time, like when you’re washing your hair or cleaning your menstrual cup. In this short contact, which is then rinsed with water, the risk of irritation is very low. Why aren’t we using “soft” surfactants? A current trend is to use ingredients that are made by marketing campaigns to sound "soft and gentle" and "used earlier". Therefore, in natural cosmetics, for example, glucosides are used, such as Coco Glucosides, Lauryl Glucosides, Decyl Glucosides, since glucosides have a glucose, i.e. a sugar base. Glucosides are much weaker in foam than sulfates, and they are not as easily thickened as sulfates. You then need polymers or gums as thickeners. However, polymers are banned in natural cosmetics and substances that are permitted in natural cosmetics, such as xanthan gum, cause the gel to leave a sticky feeling on the skin. In order to clean the Lunette Menstrual Cups thoroughly, we have chosen Ammonium lauryl sulfate (ALS) for its effectiveness as one of the ingredients in our Feelbetter Cup Cleanser. Ammonium lauryl sulfate (ALS) leaves no residue on the surface of the cup, and Ammonium lauryl sulfate (ALS) is recognized by the "Allergy, Skin and Asthma Federation" as an ingredient in cosmetic products. Many people still confuse Ammonium lauryl sulfate (ALS) with the "infamous" Sodium Lauryl Sulfate (SLS). The second surfactant we use is called cocamidopropyl betaine. This surfactant is preferred in natural cosmetics, but Ammonium lauryl sulfate (ALS) does not work well enough alone, so we paired it with the more effective Ammonium lauryl sulfate (ALS). The product has the ability to produce dense and stable foam, which allows fine and evenly distributed air bubbles to be obtained. Due to these properties, ROSULfan A is used as the main ingredient in cleansing cosmetic products. Ammonium lauryl sulfate (ALS) is dedicated to shampoos, body wash and shower gels.
ALUMINIUM CHLORIDE HEXAHYDRATE
Aluminum trichloride; Trichloroaluminum; Alluminio(Cloruro Di); Aluminium Chloride, Anhydrous; Aluminiumchlorid; Aluminum Chloride (1:3); Aluminum, (Chlorure D'); Anhydrous Aluminum Chloride; Chlorure D'aluminium; Chlorure D'aluminium, Anhydre; Tichloroaluminum, Anhydrous; Aluminiumchlorid (German); Cloruro de aluminio (Spanish); Chlorure d'aluminium CAS NO:7446-70-0
ALUMINIUM CHLORIDE X HYDRATE
Synonyms: basicaluminumchlorate;chlorhydrol;chlorhydrol,granular;chlorhydrol,impalpable;chlorohydrol;chloropentahydroxydialuminum;dialuminium;dialuminiumchloridepentahydroxide CAS: 12042-91-0
ALUMINIUM CHLOROHYDRATE
Polyaluminum chlorohydrate; PAC; Polyaluminum hydroxychloride; APP 201; Aluminum chlorohydra; Aluminum oxychloride; ALUMINIUMCHLORHYDRATE; aluminiumchlorohydrate; ALUMINUM CHLOROHYDRATE; ALUMINIUM POLYCHLORIDE; Aluminum hydroxychloride; Aluminiumhydroxychlorid8; Spray pressurefilter PAC CAS NO:1327-41-9
ALUMINIUM CHLOROHYDRATE

Aluminium chlorohydrate is a chemical compound with the formula AlCl(OH)_n, where "n" represents the degree of polymerization.
Aluminium chlorohydrate is an aluminum salt that is primarily used as an antiperspirant and a coagulant in water treatment processes.
Aluminium chlorohydrate is a white or colorless solid compound.

CAS number: 12042-91-0
EC number: 234-933-1



APPLICATIONS


Aluminium chlorohydrate is widely used as an active ingredient in antiperspirant products to control excessive sweating.
Aluminium chlorohydrate is commonly found in roll-on, stick, and spray deodorants as an effective sweat-blocking agent.

Aluminium chlorohydrate is utilized in the cosmetic industry for its ability to stabilize emulsions and improve the texture of creams and lotions.
Aluminium chlorohydrate finds application in the formulation of hair styling products such as gels and mousses to provide hold and manageability.
Aluminium chlorohydrate is used in the production of oral care products like toothpaste and mouthwash for its binding and thickening properties.

Aluminium chlorohydrate is employed in the manufacturing of gel-based formulations, such as topical gels and facial masks, to provide a smooth and spreadable texture.
Aluminium chlorohydrate is utilized in the formulation of facial cleansers and toners to enhance their cleansing and clarifying properties.

Aluminium chlorohydrate is added to certain cosmetic products to control the pH levels and improve stability and shelf life.
Aluminium chlorohydrate is used in the production of adhesive formulations, providing improved bonding and adhesion properties.

Aluminium chlorohydrate finds application in the manufacturing of paints and coatings, acting as a rheology modifier and binder for pigments.
Aluminium chlorohydrate is employed in the paper and pulp industry to enhance the formation and strength of paper sheets.
Aluminium chlorohydrate is utilized as a coagulant in water treatment processes to remove impurities and solid particles from drinking water and wastewater.

Aluminium chlorohydrate is used in the textile industry as a sizing agent to improve the smoothness and strength of fibers during weaving.
Aluminium chlorohydrate finds application in ceramic production as a binder to enhance the molding and shaping of ceramic products.
Aluminium chlorohydrate is added to drilling fluids in the oil and gas industry to increase viscosity and improve the performance of the fluid.

Aluminium chlorohydrate is utilized in the manufacturing of fire-resistant materials and coatings to improve their fire-retardant properties.
Aluminium chlorohydrate is used in the production of agricultural formulations, such as herbicides and pesticides, to enhance their effectiveness.

Aluminium chlorohydrate finds application in the formulation of personal hygiene products like wet wipes and cleansing pads for improved absorbency.
Aluminium chlorohydrate is employed in the production of adhesives for various applications, including woodworking and construction.
Aluminium chlorohydrate is added to industrial cleaning products to aid in the removal of stubborn stains and dirt.

Aluminium chlorohydrate finds application in the formulation of automotive care products, such as car waxes and polishes, for improved durability and shine.
Aluminium chlorohydrate is used in the production of fire extinguisher foams to enhance their firefighting capabilities.

Aluminium chlorohydrate is employed in the manufacturing of textile printing pastes to improve color retention and print quality.
Aluminium chlorohydrate finds application in the formulation of water-based inks for improved pigment dispersion and adhesion.
Aluminium chlorohydrate is utilized in the production of ceramic glazes to improve their flow properties and adhesion to the ceramic surface.

Aluminium chlorohydrate is used in the production of personal care wipes and facial cleansing pads to enhance their absorbency and cleansing properties.
Aluminium chlorohydrate finds application in the formulation of industrial detergents and cleaners to improve their cleaning efficiency.

Aluminium chlorohydrate is employed in the manufacturing of water-based paints and coatings as a binder and rheology modifier.
Aluminium chlorohydrate is used in the production of ceramic tiles to improve the adhesion of glazes and increase their resistance to wear.
Aluminium chlorohydrate finds application in the formulation of concrete admixtures to improve workability and reduce water absorption.

Aluminium chlorohydrate is utilized in the manufacturing of metal surface treatment solutions for cleaning and preparation before coating or painting.
Aluminium chlorohydrate is added to drilling fluids in the mining industry to increase viscosity and improve the stability of boreholes.

Aluminium chlorohydrate finds application in the formulation of construction adhesives for bonding various materials, such as wood, metal, and plastic.
Aluminium chlorohydrate is used in the production of rubber and latex products to improve their stability, viscosity, and strength.

Aluminium chlorohydrate is employed in the manufacturing of ceramics and pottery to enhance clay plasticity and reduce shrinkage during drying.
Aluminium chlorohydrate finds application in the formulation of automotive coolants and antifreeze products to improve heat transfer and prevent corrosion.
Aluminium chlorohydrate is added to cutting fluids in metalworking processes to improve lubrication and cooling during machining operations.

Aluminium chlorohydrate is used in the formulation of household and industrial cleaners as a pH adjuster and buffering agent.
Aluminium chlorohydrate finds application in the production of plastic and polymer materials to improve their flow properties during processing.

Aluminium chlorohydrate is employed in the formulation of wood preservatives to protect against fungal decay and insect attack.
Aluminium chlorohydrate is used in the production of ceramic filters for water purification, helping to remove impurities and contaminants.
Aluminium chlorohydrate finds application in the manufacturing of specialty papers, such as cigarette papers and filter papers, for improved properties.

Aluminium chlorohydrate is added to textile dyeing and printing processes to enhance color fixation and improve colorfastness.
Aluminium chlorohydrate is used in the formulation of printing inks for improved pigment dispersion and print quality.

Aluminium chlorohydrate finds application in the production of flame retardant textiles and fabrics to enhance their fire resistance properties.
Aluminium chlorohydrate is employed in the formulation of leather treatments to improve dye penetration and surface finish.

Aluminium chlorohydrate is added to drilling fluids in geothermal energy projects to provide stability and prevent fluid loss in high-temperature environments.
Aluminium chlorohydrate finds application in the production of ceramic catalysts for chemical reactions in various industrial processes.

Aluminium chlorohydrate is used in the formulation of concrete sealers and coatings to improve water repellency and durability.
Aluminium chlorohydrate is employed in the manufacturing of battery electrolytes to enhance conductivity and stability.


Aluminium chlorohydrate (ACH) has several applications across various industries.
Here are some of its primary applications:

Antiperspirants:
Aluminium chlorohydrate is widely used as an active ingredient in antiperspirant products to control perspiration and reduce body odor.

Cosmetics:
Aluminium chlorohydrate is utilized in cosmetic formulations such as deodorants, body sprays, and antiseptic solutions.

Water Treatment:
Aluminium chlorohydrate is a commonly used coagulant in water treatment processes, including municipal water treatment and wastewater treatment, to remove impurities, turbidity, and organic matter.

Paper and Pulp Industry:
Aluminium chlorohydrate finds application in the production of paper and pulp to enhance drainage and improve the retention of fibers during the papermaking process.

Ceramic Industry:
Aluminium chlorohydrate is used in the ceramic industry as a binder and flocculant to improve the strength and stability of ceramic products.

Paints and Coatings:
Aluminium chlorohydrate can be employed as a thickener, binder, and stabilizer in paint and coating formulations.

Adhesives:
Aluminium chlorohydrate can act as a binding agent in adhesive formulations, providing improved cohesion and adhesion properties.

Textile Industry:
Aluminium chlorohydrate is used as a sizing agent in the textile industry to improve the strength and smoothness of fibers during weaving.

Pharmaceutical Excipient:
Aluminium chlorohydrate can serve as an excipient in pharmaceutical formulations, providing viscosity and stability to suspensions and emulsions.

Personal Care Products:
Aluminium chlorohydrate is utilized in various personal care products such as shampoos, creams, and lotions as a stabilizer, emulsion thickener, and binder.

Construction Materials:
Aluminium chlorohydrate can be incorporated into construction materials like sealants, grouts, and mortars to enhance their performance and adhesion.

Fire Retardants:
Aluminium chlorohydrate finds application as a fire retardant additive in certain materials to improve their fire resistance properties.

Emulsion Polymerization:
Aluminium chlorohydrate is used as a coagulant and stabilizer in emulsion polymerization processes to control particle size and stability.

Agricultural Applications:
Aluminium chlorohydrate can be utilized in agriculture as an adjuvant to enhance the performance and efficacy of pesticides and herbicides.

Personal Hygiene Products:
Aluminium chlorohydrate is used in the production of personal hygiene products such as wet wipes and cleansing pads to improve their absorbency and texture.

Food Industry:
In certain countries and regions, Aluminium chlorohydrate is approved for use as a food additive, primarily as a clarifying agent in beverages and as a stabilizer in food products.

Oil and Gas Industry:
Aluminium chlorohydrate finds application in the oil and gas industry for drilling fluids, water clarification, and treatment of produced water.



DESCRIPTION


Aluminium chlorohydrate is a chemical compound with the formula AlCl(OH)_n, where "n" represents the degree of polymerization.
Aluminium chlorohydrate is an aluminum salt that is primarily used as an antiperspirant and a coagulant in water treatment processes.

Aluminium chlorohydrate is a white or colorless solid compound.
Aluminium chlorohydrate has a chemical formula of AlCl(OH)_n, where "n" can vary depending on the degree of polymerization.
Aluminium chlorohydrate is soluble in water, and its aqueous solutions are acidic.

Aluminium chlorohydrate is commonly used in antiperspirant products to reduce perspiration and control body odor.
Aluminium chlorohydrate works by forming a gel-like plug in the sweat ducts, reducing the flow of sweat to the skin surface.

Aluminium chlorohydrate is effective in controlling underarm wetness and providing long-lasting sweat protection.
Aluminium chlorohydrate is also used in cosmetic products such as deodorants and body sprays.
Aluminium chlorohydrate helps to minimize the growth of odor-causing bacteria on the skin.

In water treatment, aluminium chlorohydrate is used as a coagulant to remove impurities and turbidity from water.
Aluminium chlorohydrate aids in the precipitation and removal of suspended particles, organic matter, and dissolved substances.

Aluminium chlorohydrate is widely employed in the purification of drinking water, wastewater treatment, and industrial processes.
Aluminium chlorohydrate acts by destabilizing the particles and promoting their aggregation, allowing them to settle or be filtered out more easily.
The compound's coagulation properties make it useful in clarifying and treating swimming pool water.

Aluminium chlorohydrate can also be used in the production of paper and pulp to improve drainage and retention of fibers.
Aluminium chlorohydrate helps to increase the efficiency of the papermaking process and enhance the paper's strength and quality.

In certain formulations, aluminium chlorohydrate can be used as an ingredient in antiseptic solutions or wound healing products.
Aluminium chlorohydrate possesses astringent properties and can help reduce minor bleeding or irritation.
Aluminium chlorohydrate is compatible with a wide range of cosmetic and personal care ingredients, allowing for formulation versatility.

Aluminium chlorohydrate is generally considered safe for use in cosmetics and personal care products when used as directed.
Aluminium chlorohydrate has been approved for use by regulatory bodies such as the U.S. Food and Drug Administration (FDA) and the European Union's Scientific Committee on Consumer Safety (SCCS).

Aluminium chlorohydrate has been extensively studied for its safety profile and potential health risks, particularly concerning its absorption through the skin.
Some studies suggest a possible link between aluminium compounds and certain health conditions, although the evidence is inconclusive.
The use of aluminium chlorohydrate in antiperspirants has undergone rigorous safety assessments and is considered safe for use.

However, individuals with known sensitivities or allergies to aluminium compounds may choose alternative products.
Aluminium chlorohydrate is always recommended to follow the instructions provided by the manufacturer and consult a healthcare professional if any concerns arise.



PROPERTIES


Chemical Formula: Al2Cl(OH)5
Molecular Weight: Approximately 210.48 g/mol
Physical State: Solid
Appearance: White or pale yellow powder
Odor: Odorless
Solubility: Soluble in water
pH (1% solution): Typically around 3.5 - 4.5
Density: Varies depending on the form (powder or solution)
Melting Point: Decomposes above 100°C (212°F)
Boiling Point: Not applicable as it decomposes before boiling
Viscosity: Varies depending on the concentration and temperature
Hygroscopicity: Absorbs moisture from the air
Stability: Stable under normal conditions



FIRST AID


General Advice:

Ensure that appropriate personal protective equipment (PPE) is worn when handling aluminium chlorohydrate.
If necessary, remove the person from the contaminated area to prevent further exposure.
In case of large spills or significant exposure, contact emergency services for proper clean-up and assistance.
Always follow proper hygiene practices, such as washing hands thoroughly after handling the substance.
Keep the material safety data sheet (MSDS) or product label readily available for reference.


Inhalation:

If inhaled, remove the affected person to fresh air immediately.
If breathing is difficult, provide oxygen if available and seek medical attention.
If the person is not breathing, perform artificial respiration and seek immediate medical attention.


Skin Contact:

Remove contaminated clothing and rinse the affected skin area with plenty of water for at least 15 minutes.
If irritation or redness occurs, seek medical advice.
Wash contaminated clothing before reuse.


Eye Contact:

Rinse the eyes thoroughly with gently flowing water for at least 15 minutes, ensuring to remove any contact lenses if present and easy to do so.
If eye irritation persists, seek medical attention and provide the healthcare professional with details of the chemical involved.


Ingestion:

If swallowed, rinse the mouth thoroughly with water.
Do not induce vomiting unless directed to do so by medical personnel.
Seek immediate medical attention and provide the healthcare professional with details of the chemical ingested.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and a lab coat or protective clothing, to prevent direct contact with the substance.

Ventilation:
Ensure adequate ventilation in the working area to maintain a safe and well-ventilated environment.
Use local exhaust ventilation if necessary to control airborne concentrations.

Avoid Inhalation:
Avoid breathing in dust or fumes generated during handling.
Use mechanical handling methods or closed systems whenever possible to minimize the generation of airborne particles.

Prevent Skin and Eye Contact:
Avoid direct contact with the skin and eyes.
In case of contact, promptly rinse the affected area with water.

Hygiene Practices:
Practice good personal hygiene, including regular handwashing with soap and water after handling the substance.

Spillages and Leaks:
In the event of spillages or leaks, take appropriate measures to contain the material and prevent it from entering drains or waterways.
Use absorbent materials to clean up small spills and dispose of them properly.


Storage:

Storage Conditions:
Store aluminium chlorohydrate in a cool, dry, well-ventilated area away from heat sources, direct sunlight, and incompatible substances.
Temperature: Keep the storage temperature within the recommended range specified by the manufacturer.

Packaging:
Store the substance in tightly sealed, properly labeled containers made of compatible materials, such as high-density polyethylene (HDPE) or glass.

Compatibility:
Keep aluminium chlorohydrate away from strong bases, alkalis, oxidizing agents, and reactive metals to avoid potential reactions.

Separate from Food and Feed:
Store the substance separately from food, beverages, and animal feed to prevent contamination.

Handling Precautions:
Follow proper handling procedures when opening containers to avoid spillage or release of dust.
Use appropriate equipment, such as scoops or dedicated tools, for transferring the substance.

Storage Stability:
Check the shelf life and storage stability information provided by the manufacturer.
Follow the recommended storage duration and conditions to ensure product quality and performance.



SYNONYMS


Aluminum chlorohydrate
Aluminum hydroxychloride
Aluminum chlorhydrate
Aluminum oxychloride
Aluminum chlorhydroxide
Aluminum chloride hydroxide
Aluminum chlorohydroxide complex
Aluminum sesquichlorohydrate
Aluminic acid, basic chloride
Aluminic hydroxychloride
Aluminic chloride hydroxide
Aluminic oxychloride
Aluminic chlorohydroxide
Aluminic sesquichlorohydrate
Aluminum(III) chlorohydrate
Aluminium(III) chlorohydrate
Aluminium hydroxychloride
Aluminium chlorhydroxide
Aluminium oxychloride
Aluminium chlorohydroxide complex
Aluminium sesquichlorohydrate
Aluminic acid, chloride
Aluminium chloride hydroxide
Aluminium oxyhydrochloride
Aluminium oxychlorhydroxide
Aluminum chloride basic
Aluminum chloride hydrate
Aluminum chlorohydroxy
Aluminum chlorohydroxy complex
Aluminum hydroxychloride solution
Aluminum oxyhydroxide chloride
Aluminum oxyhydroxychloride
Aluminum oxychlorhydroxide
Aluminic acid, chlorohydroxy
Aluminic acid, oxychlorohydroxy
Aluminic chloride hydroxy
Aluminic hydroxychloride solution
Aluminic hydroxychlorohydrate
Aluminic hydroxychloro complex
Aluminic oxyhydroxychloride
Aluminic oxychlorohydroxy
Aluminum(III) chloride hydroxide
Aluminum(III) hydroxychloride
Aluminum(III) oxychlorohydroxy
Aluminum oxychloride hydroxide
Aluminum oxychlorohydroxide complex
Aluminum oxychlorohydroxy
Aluminium(III) chlorohydroxide
Aluminium(III) hydroxychloride
Aluminium(III) oxychlorohydroxy
Aluminum hydroxychlorohydrate
Aluminum oxychlorohydroxy complex
Aluminum oxyhydroxychloro complex
Aluminic acid, chlorohydroxy complex
Aluminic acid, oxychlorohydroxy complex
Aluminic hydroxychlorohydrate solution
Aluminic hydroxychloro complex
Aluminic oxychlorohydroxide complex
Aluminic oxyhydroxychlorohydrate
Aluminic oxyhydroxychloro complex
Aluminum(III) chloro hydroxy complex
Aluminum(III) hydroxy chlorohydrate
Aluminum(III) oxychloro hydroxy complex
Aluminum oxychlorohydroxy solution
Aluminum oxychlorohydroxy complex
Aluminum oxyhydroxychlorohydrate
Aluminum oxyhydroxychloro complex
Aluminium(III) chloro hydroxy complex
Aluminium(III) hydroxy chlorohydrate
Aluminium(III) oxychloro hydroxy complex
Aluminium oxychlorohydroxy solution
Aluminium oxychlorohydroxy complex
Aluminium oxyhydroxychlorohydrate
Aluminium oxyhydroxychloro complex
Aluminium chloro hydroxy complex
ALUMINIUM CHLOROHYDRATE

Aluminium chlorohydrate, also known as aluminum chlorohydroxide or aluminum hydroxychloride, is a chemical compound with the molecular formula AlCl(OH)₄.
Aluminium chlorohydrate is an inorganic compound that is commonly used as an active ingredient in antiperspirants and deodorants due to its ability to control sweat and reduce body odor.
Aluminium chlorohydrate is a white to pale yellow solid that is highly soluble in water.

CAS Number: 12042-91-0
EC Number: 234-933-1



APPLICATIONS


The primary application of Aluminium chlorohydrate is as an active ingredient in antiperspirants and deodorants.
Aluminium chlorohydrate is specifically used for controlling perspiration and reducing body odor.
By forming complexes with proteins in the sweat ducts, Aluminium chlorohydrate temporarily blocks the ducts, reducing the flow of sweat.

Apart from its use in personal care products, Aluminium chlorohydrate also finds applications in other areas:

Water treatment:
Aluminium chlorohydrate is used as a coagulant in water treatment processes.
Aluminium chlorohydrate helps in the removal of impurities and suspended particles from water, aiding in the purification process.

Paper and textile industry:
Aluminium chlorohydrate is used as a sizing agent in the production of paper and textiles.
Aluminium chlorohydrate improves the strength and durability of paper and enhances the dye absorption capacity of textiles.

Specialty chemical processes:
Aluminium chlorohydrate is utilized in various specialty chemical processes, including the production of catalysts, flame retardants, and surface treatment agents.

Adhesives:
In some adhesive formulations, Aluminium chlorohydrate is employed as a cross-linking agent or as an ingredient to improve the adhesion properties of the adhesive.

Cosmetics and skincare products:
Aluminium chlorohydrate can be found in certain cosmetic and skincare formulations, such as creams, lotions, and antiperspirant wipes, where it serves as a functional ingredient for sweat and odor control.

Water purification:
Aluminium chlorohydrate is commonly used in the treatment of drinking water, wastewater, and industrial process water.
Aluminium chlorohydrate acts as a coagulant, aiding in the removal of suspended particles, organic matter, and certain metal ions, helping to clarify and purify water.

Papermaking:
Aluminium chlorohydrate is utilized in the paper industry as a retention and drainage aid.
Aluminium chlorohydrate improves the efficiency of paper formation, enhances the retention of fibers and fillers, and reduces water consumption during the papermaking process.

Textile industry:
Aluminium chlorohydrate is employed as a mordant in textile dyeing and printing processes.
Aluminium chlorohydrate helps to fix and enhance the color fastness of dyes on fabrics, ensuring vibrant and long-lasting color results.

Adhesive formulations:
Aluminium chlorohydrate can be used as an ingredient in adhesive formulations, such as sealants and coatings.
Aluminium chlorohydrate improves the adhesion properties and provides binding strength in various applications.

Fire retardants:
Aluminium chlorohydrate is utilized in fire retardant formulations for textiles, wood, and other materials.
Aluminium chlorohydrate helps to inhibit the spread of flames and reduce smoke generation in case of fire.


Aluminium chlorohydrate is widely used as an active ingredient in antiperspirants and deodorants to control sweat and reduce body odor.
Aluminium chlorohydrate is a key component in water treatment processes, where it acts as a coagulant to remove impurities and particles from drinking water and wastewater.

Aluminium chlorohydrate finds application in the paper industry as a retention aid, improving the efficiency of paper formation and enhancing the retention of fibers and fillers.
Aluminium chlorohydrate is utilized in the textile industry as a mordant, helping to fix dyes to fabrics and improve color fastness.

Aluminium chlorohydrate is an important ingredient in fire retardant formulations for textiles, wood, and other materials, reducing the flammability and smoke generation.
Aluminium chlorohydrate is used in adhesive formulations to enhance adhesion properties and provide binding strength in various applications.
Aluminium chlorohydrate is employed in the production of specialty chemicals, including catalysts, surface treatment agents, and flame retardants.

Aluminium chlorohydrate is used in the purification of industrial process water, helping to remove contaminants and improve water quality.
Aluminium chlorohydrate finds application in the production of cosmetics and skincare products, where it aids in sweat control and odor reduction.

Aluminium chlorohydrate is utilized in the formulation of certain pharmaceutical products as a stabilizing agent or pH adjuster.
Aluminium chlorohydrate is used in the treatment of wastewater to aid in the removal of pollutants and facilitate water purification.

Aluminium chlorohydrate is employed in the manufacturing of household and industrial cleaning products for its coagulating and clarifying properties.
Aluminium chlorohydrate finds use in the production of ink and dye formulations, improving color intensity and fixation on various substrates.
Aluminium chlorohydrate is used in the manufacturing of paints and coatings as a flocculating agent and viscosity modifier.

Aluminium chlorohydrate is utilized in the production of specialty papers, such as photographic paper and filter paper, to enhance performance and quality.
Aluminium chlorohydrate is used in the formulation of certain personal care products, such as shaving creams and gels, to improve texture and consistency.

Aluminium chlorohydrate finds application in the treatment of cooling water systems to control fouling and reduce the growth of bacteria and algae.
Aluminium chlorohydrate is employed in the formulation of hair care products, such as styling gels and mousses, for its thickening and conditioning properties.

Aluminium chlorohydrate is used in the production of ceramic materials, aiding in the shaping and binding of ceramic particles.
Aluminium chlorohydrate finds application in the manufacturing of paints and varnishes as a dispersing agent and rheology modifier.
Aluminium chlorohydrate is utilized in the formulation of certain personal hygiene products, such as wet wipes and intimate cleansers, for its antimicrobial properties.

Aluminium chlorohydrate is used in the production of detergents and fabric softeners to enhance the cleaning and conditioning performance.
Aluminium chlorohydrate finds application in the treatment of industrial effluents, helping to remove pollutants and improve wastewater quality before disposal.

Aluminium chlorohydrate is employed in the formulation of agricultural chemicals, such as herbicides and fungicides, for improved stability and efficacy.
Aluminium chlorohydrate is used in the manufacturing of cosmetic powders and pressed makeup products for its binding and texture-enhancing properties.

Aluminium chlorohydrate is used in the production of ceramic glazes and enamels to enhance adhesion and improve the gloss of the final product.
Aluminium chlorohydrate finds application in the formulation of hair dyes and colorants, aiding in the fixation of color pigments on hair strands.
Aluminium chlorohydrate is utilized in the treatment of industrial wastewater from metal finishing operations to remove heavy metal contaminants.

Aluminium chlorohydrate is used in the manufacturing of plaster and gypsum products, improving the setting time and workability of the materials.
Aluminium chlorohydrate finds application in the formulation of gel-based skincare products, such as facial masks and cleansers, for its thickening and stabilizing properties.

Aluminium chlorohydrate is employed in the formulation of automotive products, such as radiator coolants and windshield washer fluids, for its anti-corrosion and anti-freeze properties.
Aluminium chlorohydrate is used in the production of construction materials, such as cementitious products, to improve their performance and durability.

Aluminium chlorohydrate finds application in the treatment of process water in various industries, including power plants, pulp and paper mills, and chemical manufacturing facilities.
Aluminium chlorohydrate is utilized in the production of detergents and cleaning agents for its ability to enhance soil removal and prevent redeposition.
Aluminium chlorohydrate is used in the formulation of cosmetic powders and pressed makeup products to improve their adhesion and texture on the skin.

Aluminium chlorohydrate finds application in the treatment of industrial gases, such as flue gas desulfurization, to remove sulfur compounds and reduce air pollution.
Aluminium chlorohydrate is employed in the manufacturing of corrosion inhibitors for metal protection in various applications, including cooling systems and pipelines.

Aluminium chlorohydrate is used in the formulation of ceramic binders and refractories, improving the strength and thermal resistance of ceramic products.
Aluminium chlorohydrate finds application in the production of pharmaceutical intermediates, where it serves as a catalyst or reactant in organic synthesis processes.

Aluminium chlorohydrate is utilized in the formulation of water-based paints and coatings as a dispersing agent and rheology modifier.
Aluminium chlorohydrate is used in the treatment of wastewater from food and beverage processing facilities to remove organic and suspended contaminants.
Aluminium chlorohydrate finds application in the manufacturing of pulp and paper, aiding in the bleaching and clarification processes.

Aluminium chlorohydrate is employed in the production of cosmetic emulsions and creams as an emulsion stabilizer and thickening agent.
Aluminium chlorohydrate is used in the formulation of agricultural adjuvants, enhancing the efficacy and absorption of pesticides and herbicides.

Aluminium chlorohydrate finds application in the treatment of mining wastewater to remove pollutants and improve water quality before discharge.
Aluminium chlorohydrate is utilized in the formulation of printing inks, improving color intensity, and ink adhesion on various substrates.
Aluminium chlorohydrate is used in the production of rubber products as a coagulating agent and viscosity modifier in the latex processing.

Aluminium chlorohydrate finds application in the treatment of industrial cooling tower water to prevent scaling and improve heat transfer efficiency.
Aluminium chlorohydrate is employed in the formulation of personal care products for pets, such as pet shampoos and conditioners, for its cleaning and deodorizing properties.
Aluminium chlorohydrate is used in the production of specialty chemicals, including textile auxiliaries, leather tanning agents, and metal surface treatments.



DESCRIPTION


Aluminium chlorohydrate, also known as aluminum chlorohydroxide or aluminum hydroxychloride, is a chemical compound with the molecular formula AlCl(OH)₄.
Aluminium chlorohydrate is an inorganic compound that is commonly used as an active ingredient in antiperspirants and deodorants due to its ability to control sweat and reduce body odor.
Aluminium chlorohydrate is a white to pale yellow solid that is highly soluble in water.

The compound is formed through the reaction of aluminum hydroxide with hydrochloric acid.
Aluminium chlorohydrate consists of aluminum cations (Al³⁺) and chloride and hydroxide anions (Cl⁻ and OH⁻) in its structure.
The exact composition of aluminium chlorohydrate can vary, with different products having different levels of aluminum and chloride content.

Aluminium chlorohydrate works by forming complexes with proteins in the sweat ducts, resulting in the temporary blockage of the ducts and reducing the flow of sweat.
This helps to control perspiration and minimize the occurrence of body odor.

It is important to note that the use of aluminium chlorohydrate in antiperspirants has been the subject of some debate and scrutiny, particularly regarding its potential link to health concerns.
However, regulatory bodies such as the U.S. Food and Drug Administration (FDA) have deemed it safe for use in cosmetics within certain concentration limits.
Aluminium chlorohydrate may also find applications in water treatment processes as a coagulant, in the production of paper and textiles as a sizing agent, and in some specialty chemical processes.


Aluminium chlorohydrate is a white to pale yellow solid compound.
Aluminium chlorohydrate is commonly used as an active ingredient in antiperspirants and deodorants.

Aluminium chlorohydrate is known for its astringent properties.
Aluminium chlorohydrate is produced by the reaction of aluminium hydroxide with hydrochloric acid.
Aluminium chlorohydrate contains aluminium cations (Al³⁺) and chloride and hydroxide anions (Cl⁻ and OH⁻) in its structure.

Aluminium chlorohydrate is a widely used ingredient in personal care products.
Aluminium chlorohydrate is easy to incorporate into formulations.

Aluminium chlorohydrate is not flammable.
Aluminium chlorohydrate is regulated and approved for use in cosmetics by regulatory bodies.
Aluminium chlorohydrate provides a reliable solution for sweat and odor control, promoting a fresh feeling throughout the day.



PROPERTIES


Chemical formula: Al2Cl(OH)5
Molecular weight: Approximately 210.48 g/mol
Physical state: Typically a white or pale yellow solid
Odor: Odorless
Solubility: Soluble in water
Density: Varies depending on the concentration and form (solid or solution)
pH: Acidic to neutral (pH range typically between 3.5 and 5.0)
Melting point: Decomposes upon heating
Boiling point: Decomposes upon heating
Vapor pressure: Low, negligible at room temperature
Stability: Stable under normal storage and handling conditions
Hygroscopicity: Attracts and absorbs moisture from the air
Viscosity: Varies depending on the concentration and temperature
Electrical conductivity: Low electrical conductivity in water
Heat of combustion: Releases heat upon combustion
Flammability: Non-flammable
Flash point: Not applicable (solid)
Explosive properties: Not explosive
Oxidizing properties: Not oxidizing



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air immediately.
If breathing is difficult, provide oxygen if available and seek medical attention.
If the person is not breathing, perform artificial respiration and seek immediate medical attention.


Skin contact:

Remove contaminated clothing and rinse the affected area with plenty of water for at least 15 minutes.
Wash thoroughly with mild soap and water.
Seek medical attention if irritation, redness, or discomfort persists.


Eye contact:

Rinse the eyes gently with water for at least 15 minutes, lifting the eyelids occasionally to ensure thorough rinsing.
Remove contact lenses, if present and easily removable.
Seek immediate medical attention, even if the person does not show immediate symptoms.


Ingestion:

Rinse the mouth with water.
Do not induce vomiting unless instructed to do so by medical personnel.
Seek immediate medical attention.

Provide medical personnel with information about the ingested substance, its composition, and the amount ingested.



HANDLING AND STORAGE


Handling:

Use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat or protective clothing, when handling Aluminium chlorohydrate (ACH).
Avoid inhalation of dust or vapors.
Work in a well-ventilated area or use local exhaust ventilation if necessary.

Avoid direct contact with skin and eyes. In case of contact, promptly rinse the affected area with water.
Prevent the release of Aluminium chlorohydrate into the environment.

Use containment measures such as barriers or secondary containment to prevent spills or leaks.
Handle Aluminium chlorohydrate with care to avoid generating dust or dispersing it into the air.
Avoid ingestion of ACH. Do not eat, drink, or smoke in areas where ACH is being handled.


Storage:

Store Aluminium chlorohydrate in a cool, dry, well-ventilated area away from incompatible substances.
Keep containers tightly closed and properly labeled to prevent accidental exposure.

Store AAluminium chlorohydrate away from sources of heat, ignition, or open flames.
Ensure that storage areas are equipped with appropriate fire suppression and spill containment measures.

Store Aluminium chlorohydrate separately from strong acids, bases, oxidizing agents, and reactive substances to prevent chemical reactions.
Follow local regulations and guidelines for the storage of hazardous substances.

Keep ACH out of reach of unauthorized personnel, children, and pets.
Store Aluminium chlorohydrate in original or approved containers to maintain product integrity and avoid cross-contamination.

Regularly inspect storage areas for signs of leaks, corrosion, or damage to containers.
Address any issues promptly and appropriately.
Have appropriate fire extinguishing equipment and spill response materials readily available near the storage area.



SYNONYMS


Aluminum chlorhydrate
Aluminum chloride hydroxide
Aluminum sesquichlorohydrate
Aluminum hydroxychloride
Aluminum oxychloride
Aluminum oxychlorohydrate
Aluminum chloride oxide
Aluminum basic chloride
Aluminum chlorohydrol
Aluminum chlorohydroxide
Aluminum chloroxyhydroxide
Aluminum chlorohydroxide sulfate
Aluminum chlorohydroxide phosphate
Aluminum polyoxychloride
Aluminum polychlorohydrate
Aluminum chloro-oxido-hydroxy
Aluminum chloro-oxido-hydroxy sulfate
Aluminum chloro-oxido-hydroxy phosphate
Aluminium chlorohydroxy sulfate
Aluminium chloro-oxido-hydroxy
Aluminium chloro-oxido-hydroxy sulfate
Aluminium chloro-oxido-hydroxy phosphate
Aluminum(III) chlorohydrate
Aluminum(III) chloro-oxido-hydroxy
Aluminum(III) chloro-oxido-hydroxy sulfate
Aluminum chlorhydroxide
Aluminum chloride hydroxy
Aluminum chloride oxide hydroxide
Aluminum chloride polyhydroxy complex
Aluminum chloro hydroxy
Aluminum hydroxy chlorides
Aluminum oxychloro hydroxy
Aluminum oxychloro hydroxy sulfate
Aluminum oxychloro hydroxy phosphate
Aluminum oxyhydroxy chlorides
Aluminum polyoxyhydroxy chloride
Aluminum polychlorohydroxy complex
Aluminum polychloro hydroxy
Aluminum polychloro hydroxy sulfate
Aluminum polychloro hydroxy phosphate
Aluminium chloro hydroxy sulfate
Aluminium chloro hydroxy phosphate
Aluminium chloro hydroxy complex
Aluminium hydroxy chlorides
Aluminum(III) chlorohydroxy
Aluminum(III) chlorohydroxy sulfate
Aluminum(III) chlorohydroxy phosphate
Aluminum(III) chloroxyhydroxy
Aluminum(III) chloroxyhydroxy sulfate
Aluminum(III) chloroxyhydroxy phosphate
ALUMINIUM CHLOROHYDRATE 50%
Stearic acid, aluminum salt; Aluminum tristearate; Monoaluminum stearate; Octadecanoic acid, aluminum salt; Hydroxyaluminiumstearat; Aluminiumstearat; Estearato de hidroxialuminio; Estearato de aluminio; Estearato de hidroxialuminio; Stéarate d'aluminium CAS NO:300-92-5; 36816-06-5
ALUMINIUM DISTEARAT
Hydrated alumina; Alumina hydrate; Alumina trihydrate; ATH; Aluminum hydrate; Aluminum trihydrate; Alhydrogel; Superfos; Amphogel; Aluminum (III) hydroxide; Amorphous alumina; Trihydrated Alumina; Trihydroxyaluminum CAS NO:21645-51-2
ALUMINIUM HYDROXIDE
CAS Number: 21645-51-2
EC number: 244-492-7
Chemical formula: Al(OH)3
Molar mass: 78.00 g/mol

Aluminium hydroxide, Al(OH)3, is found in nature as the mineral gibbsite (also known as hydrargillite) and its three much rarer polymorphs: bayerite, doyleite, and nordstrandite.
Aluminium hydroxide is amphoteric, i.e., it has both basic and acidic properties.
Closely related are aluminium oxide hydroxide, AlO(OH), and aluminium oxide or alumina (Al2O3), the latter of which is also amphoteric.
Aluminum hydroxide, the formulation of which is Al(OH)3, can be found in nature in the following forms: gibbsite, which is a mineral, and doyleite, nordstrandite and bayerite, all of which are rare polymorphs. Based on its properties, we can say that aluminum hydroxide appears to be an antacid. It has various uses, primary among which is medical application.

Aluminium hydroxide can also reduce the amount of phosphate which your body absorbs from the food you eat.
Aluminium hydroxide combines with phosphate in your stomach, and this is then removed instead of being absorbed.
Although aluminium hydroxide is sometimes prescribed for this purpose in people with certain kidney diseases, other medicines are usually used in preference to it.

Uses of Aluminium hydroxide:
Fire retardant filler:
Aluminium hydroxide also finds use as a fire retardant filler for polymer applications.
Aluminium hydroxide is selected for these applications because it is colorless (like most polymers), inexpensive, and has good fire retardant properties.
Magnesium hydroxide and mixtures of huntite and hydromagnesite are used similarly.
Aluminium hydroxide decomposes at about 180 °C (356 °F), absorbing a considerable amount of heat in the process and giving off water vapour.
In addition to behaving as a fire retardant, Aluminium hydroxide is very effective as a smoke suppressant in a wide range of polymers, most especially in polyesters, acrylics, ethylene vinyl acetate, epoxies, polyvinyl chloride (PVC) and rubber.

Precursor to Al compounds:
Aluminium hydroxide is a feedstock for the manufacture of other aluminium compounds: calcined aluminas, aluminium sulfate, polyaluminium chloride, aluminium chloride, zeolites, sodium aluminate, activated alumina, and aluminium nitrate.
Freshly precipitated aluminium hydroxide forms gels, which are the basis for the application of aluminium salts as flocculants in water purification.
This gel crystallizes with time.
Aluminium hydroxide gels can be dehydrated (e.g. using water-miscible non-aqueous solvents like ethanol) to form an amorphous aluminium hydroxide powder, which is readily soluble in acids.
Heating converts it to activated aluminas, which are used as desiccants, adsorbent in gas purification, and catalyst supports.

Pharmaceutical:
Under the generic name "algeldrate", aluminium hydroxide is used as an antacid in humans and animals (mainly cats and dogs).
Aluminium hydroxide is preferred over other alternatives such as sodium bicarbonate because Al(OH)3, being insoluble, does not increase the pH of stomach above 7 and hence, does not trigger secretion of excess acid by the stomach.
Aluminium hydroxide reacts with excess acid in the stomach, reducing the acidity of the stomach content, which may relieve the symptoms of ulcers, heartburn or dyspepsia.
Such products can cause constipation, because the aluminium ions inhibit the contractions of smooth muscle cells in the gastrointestinal tract, slowing peristalsis and lengthening the time needed for stool to pass through the colon.
Some such products are formulated to minimize such effects through the inclusion of equal concentrations of magnesium hydroxide or magnesium carbonate, which have counterbalancing laxative effects.

Aluminium hydroxide is also used to control hyperphosphatemia (elevated phosphate, or phosphorus, levels in the blood) in people and animals suffering from kidney failure.
Normally, the kidneys filter excess phosphate out from the blood, but kidney failure can cause phosphate to accumulate.
The aluminium salt, when ingested, binds to phosphate in the intestines and reduce the amount of phosphorus that can be absorbed.

Precipitated aluminium hydroxide is included as an adjuvant in some vaccines (e.g. anthrax vaccine).
One of the well-known brands of aluminium hydroxide adjuvant is Alhydrogel, made by Brenntag Biosector.
Since Aluminium hydroxide absorbs protein well, it also functions to stabilize vaccines by preventing the proteins in the vaccine from precipitating or sticking to the walls of the container during storage.
Aluminium hydroxide is sometimes called "alum", a term generally reserved for one of several sulfates.

Vaccine formulations containing aluminium hydroxide stimulate the immune system by inducing the release of uric acid, an immunological danger signal.
This strongly attracts certain types of monocytes which differentiate into dendritic cells.
The dendritic cells pick up the antigen, carry it to lymph nodes, and stimulate T cells and B cells.
Aluminium hydroxide appears to contribute to induction of a good Th2 response, so is useful for immunizing against pathogens that are blocked by antibodies.
However, Aluminium hydroxide has little capacity to stimulate cellular (Th1) immune responses, important for protection against many pathogens, nor is it useful when the antigen is peptide-based.

Chemical Properties of Aluminium hydroxide:
There are many different forms of aluminum oxide, including both crystalline and non-crystalline forms.
Aluminium hydroxide’s an electrical insulator, which means it doesn’t conduct electricity, and Aluminium hydroxide also has relatively high thermal conductivity.
In addition, in Aluminium hydroxides crystalline form, corundum, its hardness makes it suitable as an abrasive.
The high melting point of aluminum oxide makes it a good refractory material for lining high-temperature appliances like kilns, furnaces, incinerators, reactors of various sorts, and crucibles.
The chemical formula for aluminum hydroxide is Al(OH)₃.

Aluminium hydroxide is taken for indigestion.
Aluminium hydroxide is also taken to control high phosphate levels in people with kidney disease.

Aluminium hydroxide is an antacid, which means that it neutralises excess stomach acid associated with indigestion.
Aluminium hydroxide also helps to protect the lining of your stomach from acid irritation.

Properties of aluminum hydroxide:
The purified aluminum hydroxide has form of bulky powder of white color or granules with density nearly 2.42 g per mL.
Aluminum hydroxide won’t dissolve in water, but will dissolve only in bases and acids.
You can expect aluminum hydroxide to act as an amphoteric substance in water.
If a strong base is present, aluminum hydroxide will act as an acid.
And if a strong acid is present, Aluminium hydroxide will act as a strong base.
Aluminum hydroxide should be handled with caution because its exposure can cause irritation.
However, only minor and residual injuries will be present.
As for flammability, aluminum hydroxide is not flammable and will not burn.
Besides, aluminum hydroxide is not reactive, therefore, it is stable in both fire and water conditions.

Uses of Aluminium hydroxide:
-Aluminium hydroxide is used as a flame retardant in plastics.
-Aluminium hydroxide is used as an antacid.
-Aluminium hydroxide is used in aluminium Hydroxide gel.
-Aluminium hydroxide is used to manufacture activated alumina.
-Aluminium hydroxide is used as a filler in cosmetics.
-Aluminium hydroxide is used as a chemical intermediate.
-Aluminium hydroxide is used as a soft abrasive for plastics.
-Aluminium hydroxide is used in glass additive to increase resistance to thermal shock.
-Aluminium hydroxide is used in waterproofing fabrics.
-Aluminium hydroxide is used in the manufacturing of glass.

Al(OH)3: Aluminium hydroxide
Molecular weight of Al(OH)3: 78.00 g/mol
Density of Aluminium hydroxide: 2.42 g/dm3
Flashpoint of Aluminium hydroxide: Non-flammable
Melting Point of Aluminium hydroxide: 300 °C

Applications of aluminum hydroxide:
Aluminum hydroxide has plenty of applications; some people believe that these uses are really endless.
Just to illustrate the broadness of the uses, we can say that aluminum hydroxide is used as mordant in dyes, purifier for water, ingredient for cosmetics, and even in as an element for processes in photography.
There are also applications of minor character in ceramics and construction.
But the most important field where aluminum hydroxide is applied is medicine.

Aluminum Hydroxide Applications in medicine:
Given that aluminum hydroxide is able to neutralize acids, it serves as a natural antacid.
Aluminum hydroxide also has a very useful property as it stimulates the immune system of human.
Besides, various vaccines, including those that are used to treat hepatitis B, hepatitis A, and tetanus, are prepared using aluminum hydroxide.
Aluminium hydroxide can be also used for the treatment of kidney patients who have high level of phosphates in blood due to renal failure.
This useful feature exists due to the ability of aluminum hydroxide to bind with phosphates.
After binding with aluminum hydroxide, phosphates are flushed out of the human body easily.

Cosmetics applications of Aluminium hydroxide:
There are various applications for aluminum hydroxide in the field of cosmetics.
Aluminum hydroxide is most frequently used for the production of lipsticks, make-ups, and other products for skin care.
Aluminium hydroxide is used there because it is totally stable and non toxic for people.
Sometimes aluminum hydroxide manufacturers of cosmetics also use aluminum hydroxide to produce cleansers for skin, suntan products, body lotions, and moisturizers.
Personal care products, for example, shampoos, toothpastes, deodorants and many others, also involve using of aluminum hydroxide.
Aluminum hydroxide is also sometimes used for protection of human skin.

Applications of Aluminium hydroxide in industry:
Concrete could not be produced without aluminum hydroxide.
On the stage of production of concrete aluminum hydroxide is added to cement.
Aluminium hydroxide is also very useful because cement with aluminum hydroxide addition dries rapidly if it is being exposed to heat.
Ceramics and glass of both industrial and home application is manufactured using aluminum hydroxide.
The most useful feature of aluminum hydroxide when it is added to glass consists in the fact that it makes glass heat-resistant.
Aluminium hydroxide is possible because, as have been already mentioned, aluminum hydroxide is not flammable and has high melting point.
Aluminum hydroxide combined with polymers appears to be a very good fire retardant.

Uses of Aluminium hydroxide in textile field:
Don’t forget that aluminum hydroxide doesn’t dissolve in water.
For this reason, Aluminium hydroxide can be applied in textiles by adding it in order to produce waterproof clothes.
Besides, when Aluminium hydroxide is needed to bind colors of vegetable dyes to fabric, aluminum hydroxide will also be very useful.
In this case, aluminum hydroxide is used as a mordant.
Any mordant is used in cases when fabrics are resistant to dyes.
In such situations, a mordant allows penetrating fabric by the dye.
Another instance of aluminum hydroxide usage is when it is used to make some dyes fire-resistant.

Aluminum Hydroxide Formula Other field of applications:
Given how actively aluminum hydroxide is used in various fields we could not omit other field of its applications.
Apart from what we have already mentioned above, aluminum hydroxide, as well as any other aluminum compound, is used to purify water in order to remove particles and various kinds of impurities.
In manufacturing of inks aluminum hydroxide acts as an extender and preservative.
Aluminum hydroxide can be also used as chromatography in laboratories in order to separate chemicals into different compounds.

Reactions in humans:
Unlike some other aluminum compounds, aluminum hydroxide causes no adverse reaction in humans, at least towards the majority of persons.
Aluminium hydroxide is very broadly used in many fields of life and has plenty of applications in home use and industry.
Most people may not know what aluminum hydroxide is or where this compound is used, but we already know it and useful features of aluminum hydroxide are obvious to all people interested in this subject.

Medical precautions of aluminum hydroxide:
There is no surprise that the most important application of aluminum hydroxide is its medical application.
Even though aluminum hydroxide is relatively safe to humans and is applied in various fields of human life, oral administration of aluminum hydroxide should be completed cautiously.
Aluminium hydroxide is always recommended to advise your doctor before starting taking aluminum hydroxide or if any problems occur during the taking.
If you have any health problems related to kidneys, including stones, constipation or disease, you should see a doctor or get an advice of a pharmacist before taking any medicine that contains aluminum hydroxide.
Besides, the doctor’s advice is also necessary in case you are dehydrated or drink alcohol on a regular basis.

Nomenclature:
CAS No.: 21645-51-2
Molecular Formula: Al(OH)3
Molecular Weight: 78
Synonyms: Aluminic acid, Aluminic hydroxide, Aluminium(III) hydroxide, Aluminum hydroxide,Hydrated alumina, Orthoaluminic acid
Physical Property:
Physical state: White amorphous powder
Melting Point: 300°C
Solubility: in water, Soluble in acids, alkalis, HCl and H2SO4
Acidity (pKa): >7
Flash point: Noninflammable

Application & Use of Aluminium hydroxide:
Mainly used as an Active medicament in an Antacid Formulations, also used in manufacturing of Lake colors, Inks, catalysts carrier etcs.
Aluminum hydroxide is used to treat symptoms of increased stomach acid, such as heartburn, upset stomach, sour stomach, or acid indigestion.
Aluminum hydroxide is also used to reduce phosphate levels in people with certain kidney conditions.

Advantage and Disadvantages of Aluminium hydroxide:
Aluminium hydroxide is used to treat the symptoms of too much stomach acid such as stomach upset, heartburn, and acid indigestion.
Aluminum hydroxide is an antacid that works quickly to lower the acid in the stomach.
Stop using the medication and call your doctor at once if you have a serious side effect such as: severe stomach pain or constipation; bloody, black, or tarry stools; coughing up blood that looks like coffee grounds; pain when you urinate; extreme drowsiness; tired feeling, loss of appetite, and muscle weakness

Taking aluminum hydroxide for more than two weeks with no advice of your doctor is strongly not recommended.
Besides, you should not take any other medications when taking aluminum hydroxide.
If you are pregnant or planning to become pregnant during your treatment with aluminum hydroxide, you must have an advice of your doctor.
The same should be done if you are a breast-feeding mother.
Effect of aluminum hydroxide on a nursing baby can be harmful.
For this reason, you should consult the doctor of yours in such a situation.

Aluminium hydroxide (Al(OH)3 – ATH) is the most widely used inorganic flame retardant in the World.
ATH is cost effective and non toxic flame retardant can be used in wide variety of molding compounds such as rubber, polyster and epoxy composites, polyurethane foams, latex based formulations, silicone, wall coverings, wire and cables.
ATH flame retardants are in the non halogenated and low smoke and fume (LSF) category which is important for human health and environment.

Some important properties of Aluminium hydroxide for flame retardants are listed below:
-Decomposition temperature,
-Toxicity (effects on human health and environment),
-Cost,
-Specific gravity,
-Optical properties (colour, refractive index etc),
-Effect on mechanical and electrical properties of the final product

What does aluminium hydroxide do?
Aluminium is a metal that occurs naturally.
The antacid is the hydroxide of aluminium.
Aluminium hydroxide is used in the treatment of heartburn, stomach pain, sore stomach or indigestion with acid.
Aluminium hydroxide is also used in humans with other kidney disorders to reduce phosphate levels.

Is Aluminium hydroxide safe in cosmetics?
The synthetic ingredient which acts as an opacifier.
Primary applications include agent and absorbent for painting.
There is no known skin toxicity to the aluminium hydroxide.

What is another name for aluminium hydroxide?
Aluminium hydroxide is an over-the-counter antacid drug used to treat peptic ulcer and hyperphosphatemia.

Is aluminium hydroxide a weak base?
Aluminium hydroxide has molecular formula Al(OH)3 as a chemical compound.
For example, in aluminium hydroxide the hydroxide (OH) can act as a weak base when reacting with the strong acid, hydrochloric acid (HCl).
A weak base is a base that partially dissociates in solution, or breaks apart.

Applications of Aluminium hydroxide:
-Construction & Civil Engineering>Others
-Daily Life>Others
-Daily Life>Sanitary products
-Daily Life>Public hygiene products
-Industrial Chemicals>Others
-Industrial Chemicals>Adhesives
-Industrial Chemicals>Plasticizers
-Industrial Chemicals>Rubber chemicals
-Industrial Chemicals>Polymer additives
-IT-related Materials>Others
-IT-related Materials>Electronic materials
-IT-related Materials>Display materials
-IT-related Materials>Semiconductor processing materials
-IT-related Materials>Lithium-ion secondary battery materials
-Environment & Energy>Others
-Environment & Energy>Lithium-ion secondary battery materials

PRODUCTION METHOD of Aluminium hydroxide:
Conventional powder production methods are used for the production.
Aluminum hydroxide (ATH) powders can be used as flame retardant additive for polymer applications and production of aluminum oxide powders.

CHEMICAL AND PHYSICAL PROPERTIES of Aluminium hydroxide:
Chemical purity: > %99.5
Whiteness: > %97
Particle size: 20-25 µm

APPLICATIONS of Aluminium hydroxide:
Raw material for alumina production
Flame retardant applications

Aluminium hydroxide is a white crystalline product.
Aluminium hydroxide is also known as hydrated alumina, aluminium hydrate or alumina tri-hydrate (ATH).
Aluminium hydroxide is typically used as a raw material for the production of other alumina based chemicals such as calcined alumina, aluminium sulfate, poly aluminium chloride (PAC), aluminium fluoride and synthetic zeolite.
Aluminium hydroxides chemical formula is Al2O3•3H2O or Al(OH)3.

Formula:
AlH3O3
H3AlO3
Net Charge: 0
Average Mass: 78.00356
Monoisotopic Mass: 77.98976
InChI: InChI=1S/Al.3H2O/h;3*1H2/q+3;;;/p-3
InChIKey: WNROFYMDJYEPJX-UHFFFAOYSA-K
SMILES: [H]O[Al](O[H])O[H]

How to take aluminum hydroxide?
You should take this aluminum compound only in the way this is specified on its label or how your doctor prescribes it.
Don’t exceed the dose prescribed by your doctor and don’t take aluminum hydroxide for longer than it was prescribed.

To be sure that your dose is accurate, measure it with medicine spoon or cup instead of regular spoon.
Don’t have a special medical device for measuring? Buy it or ask your doctor to provide it.
Aluminum hydroxide should be taken with full glass of water.
Usually aluminum hydroxide is taken before bedtime or between meals.
Don’t take Aluminium hydroxide longer than two months if your doctor hasn’t advised you otherwise.
Aluminum hydroxide should be stored away from heat, light, and moisture.

Don’t worry if you have missed a dose.
Usually aluminum hydroxide should not be taken regularly, but if it is, take it as soon as you remember about it.
But if the time for the next dose has almost come, skip the missed dose.
In case of an overdose with aluminum hydroxide, you should contact poison help service or seek emergency medical help.
The symptoms of an overdose with aluminum hydroxide are weight loss, mood changes, confusion, constipation, and urinating less than usually or not urinating at all.

What is aluminum hydroxide?
Aluminum is a naturally occurring mineral.
Aluminum hydroxide is an antacid.
Aluminum hydroxide is used to treat heartburn, upset stomach, sour stomach, or acid indigestion.
Aluminum hydroxide is also used to reduce phosphate levels in people with certain kidney conditions.
Aluminum hydroxide may also be used for purposes not listed in this medication guide.

Structure of Aluminium hydroxide:
Al(OH)3 is built up of double layers of hydroxyl groups with aluminium ions occupying two-thirds of the octahedral holes between the two layers.
Four polymorphs are recognized.
All feature layers of octahedral aluminium hydroxide units, with hydrogen bonds between the layers.
The polymorphs differ in terms of the stacking of the layers.

All forms of Al(OH)3 crystals are hexagonal:
-gibbsite is also known as γ-Al(OH)3 or α-Al(OH)3
-bayerite is also known as α-Al(OH)3 or β-alumina trihydrate
-nordstrandite is also known as Al(OH)3
-doyleite

What is aluminum hydroxide?
Aluminum hydroxide is an over-the-counter oral antacid and phosphate binder, most commonly used to treat high phosphate levels secondary to kidney dysfunction (abnormal or impaired function of the kidneys).
Aluminium hydroxide can also be used to reduce stomach acid production.

Aluminium hydroxides use in cats, dogs, or small mammals to treat high phosphate levels is 'off label' or 'extra label'.
Many drugs are commonly prescribed for off label use in veterinary medicine.
In these instances, follow your veterinarian’s directions and cautions very carefully as their directions may be significantly different from those on the label.

How is aluminum hydroxide given?
Aluminum hydroxide is given by mouth in the form of a liquid gel or in powder form mixed with food.
Aluminium hydroxide can also be compounded into capsules.
Aluminium hydroxide should be given immediately before food or mixed into the food.
Aluminium hydroxide should take effect within 1 to 2 hours; however, effects may not be visibly obvious and therefore laboratory tests may need to be done to evaluate this medication’s effectiveness.

Hydrargillite, once thought to be aluminium hydroxide, is an aluminium phosphate.
Nonetheless, both gibbsite and hydrargillite refer to the same polymorphism of aluminium hydroxide, with gibbsite used most commonly in the United States and hydrargillite used more often in Europe.
Hydrargillite is named after the Greek words for water (hydra) and clay (argylles).

What is aluminum hydroxide?
Aluminum hydroxide is an antacid available in over-the-counter (OTC) medicines that relieve heartburn, acid indigestion, sour stomach, and upset stomach.
Aluminum hydroxide can be found in heartburn medicines that contain more than one antacid active ingredient.
Aluminium hydroxide can also be found in medicines that treat other symptoms, such as gas.

What is aluminum hydroxide used to treat?
-Heartburn
-Acid Indigestion
-Sour Stomach
-Upset Stomach

What is Aluminium Hydroxide?
Al(OH)3 is amphoteric in nature with chemical name Aluminium hydroxide.

Aluminium hydroxide is also called Aluminic acid or Aluminic hydroxide or Aluminium (III) hydroxide.
Aluminium hydroxide is found in nature in the form of mineral gibbsite and its polymorphs viz doyleite, nordstrandite, and bayerite.
Aluminic hydroxide is an amorphous powder white.
Aluminium hydroxide is insoluble in water but soluble in alkaline and acidic solutions.

Properties of Aluminium hydroxide:
Aluminium hydroxide is amphoteric.
In acid, Aluminium hydroxide acts as a Brønsted–Lowry base.
Aluminium hydroxide neutralizes the acid, yielding a salt:
3 HCl + Al(OH)3 → AlCl3 + 3 H2O

In bases, Aluminium hydroxide acts as a Lewis acid by binding hydroxide ions:
Al(OH)3 + OH− → Al(OH)4−

ALUMINIUM HYDROXIDE
Aluminium hydroxide or aluminium hydroxycarbonate, is the most widely used antacid active.
Aluminium hydroxide is available as both a suspension and powder and maybe used alone or in combination with magnesium hydroxide.
The widespread use of aluminium hydroxide gel in the formulation of antacids is based on its excellent pharmacological properties, which have been confirmed repeatedly over many years of administration.
Aluminium hydroxide gel is an effective neutralizer and buffer of gastric hydrochloric acid, with no known harmful side effects.
We offer a vast selection of aluminium hydroxide grades with a variety of properties.

ALUMINIUM HYDROXIDE POWDER:
Aluminium hydroxide powders are manufactured from suspensions via defined drying processes which result in powders with varying density and particle size characteristics.
The powders are primarily used in the production of antacid tablets, preferably after pre-granulation.

Preferred IUPAC name:
Aluminium hydroxide

Systematic IUPAC name:
Trihydroxidoaluminium

CAS Number: 21645-51-2
CHEBI: 33130
ChEMBL: ChEMBL1200706
ChemSpider: 8351587
DrugBank: DB06723
ECHA InfoCard: 100.040.433
KEGG: D02416
PubChem CID: 10176082
RTECS number: BD0940000
UNII: 5QB0T2IUN0
CompTox Dashboard (EPA): DTXSID2036405

How should I take aluminum hydroxide?
Use of Aluminium hydroxide exactly as directed on the label, or as prescribed by your doctor.
Aluminum hydroxide is usually taken between meals or at bedtime.
Take aluminum hydroxide with a full glass (8 ounces) of water.
Shake the oral suspension (liquid) before you measure a dose.
Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
Do not take aluminum hydroxide for longer than 2 weeks without your doctor's advice.
Store at room temperature away from moisture, heat, and light.

Chemical formula: Al(OH)3
Molar mass: 78.00 g/mol
Appearance: White amorphous powder
Density: 2.42 g/cm3, solid
Melting point: 300 °C (572 °F; 573 K)
Solubility in water: 0.0001 g/100 mL
Solubility product (Ksp): 3×10−34
Solubility: soluble in acids and alkalis
Acidity (pKa): >7
Isoelectric point: 7.7

Color: White
pH: 8.5 to 10 (5% aq. suspension)
Linear Formula: Al(OH)3
Merck Index: 15,338
Solubility Information: Solubility in water: insoluble
Formula Weight: 78
Physical Form: Powder
Percent Purity: ≥63.5% (Al2O3)
Grade: Extra Pure
Loss on Ignition: 36.5% max.
Packaging: Plastic bottle
Water Soluble Substances: 0.2% max.
Chemical Name or Material: Aluminium hydroxide

Before taking aluminium hydroxide
To make sure this is the right treatment for you, before you take aluminium hydroxide capsules it is important that your doctor or pharmacist knows:
-If you are pregnant or breastfeeding.
-If you have any problems with the way your liver works or any problems with the way your kidneys work.
-If you have been told you have low levels of phosphate in your blood.
-If you have ever had an allergic reaction to a medicine.
-If you are taking any other medicines.
This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.

How to take aluminium hydroxide
For indigestion in adults, take one capsule four times a day with meals and one at bedtime.
The capsules are not suitable for children to take as an antacid.
Antacids are best taken when symptoms are likely to occur.
If you are taking aluminium hydroxide to reduce the amount of phosphate in your body, your doctor will tell you how many capsules to take each day.
You could be asked to take between 4-20 capsules a day.
Take the capsules spaced out throughout the day with your meals.
Aluminium hydroxide can interfere with other medicines taken at the same time and can prevent them form being absorbed properly.
Aluminium hydroxide is best if you leave two hours between taking aluminium hydroxide and any other medicines.

Other names:
Aluminic acid
Aluminic hydroxide
Aluminium(III) hydroxide
Aluminium hydroxide
Aluminum trihydroxide
Hydrated alumina
Orthoaluminic acid

Aluminium hydroxide is regarded as being the most important mineral flame retardant in the world and, thanks to its freedom from halogens, it is environmentally friendly and is characterized by its high efficiency as a smoke gas suppressant.
Aluminium hydroxide is made from bauxite in accordance with the Bayer process.
Besides the flame retardant property, the excellent features of aluminium hydroxide are its high degree of whiteness and low degree of hardness.
In addition, dehydration takes place at 200°C.

Properties of Aluminium hydroxide:
-low degree of hardness, 3
-density of 2.4 g/cm3
-high degree of whiteness (colour value Y > 94)
-thermal coefficient of expansion 15*10-6K-1 (at a temp. of 20–300°C)
-flame retardant

What is Aluminium Hydroxide?
Aluminium hydroxide adjuvant comprises aluminium hydroxide gel in saline solution.
Moreover, aluminium hydroxide is an inorganic salt that has usage as an antacid.
Also, Aluminium hydroxide is a basic compound that neutralizes the hydrochloric acid in gastric secretions.
Aluminium hydroxide is amphoteric in nature.

Main applications of Aluminium hydroxide:
-cables for example made of PVC
-textile applications
-solid surface composites made of PMMA
-epoxy casting resins
-SMC/BMC and latex

Product Properties:
Physical state: Liquid
Form: Liquid
Al2O3: 10% (w/w)
Charge: +1350
Colour: Colourless to light yellow
Odour: Not significant
pH: >= 2
Melting point/freezing point: < 0 °C (< 32 °F)
Boiling point, initial boiling point: 100 – 120 °C (212 – 248 °F)
Density: 1200 – 1400 kg/m3 @ 20 oC
Solubility (water): Miscible

Indications of Aluminium hydroxide:
Aluminum hydroxide is often administered orally for the temporary relief of heartburn or gastroesophageal reflux.
Aluminium hydroxide may be used topically, temporarily, to protect and relieve chafed and abraded skin, minor wounds and burns, and skin irritations resulting from friction and rubbing.
Patients may also receive Aluminium hydroxide to treat chemo-induced oral mucositis in the form of a mouthwash.
Additionally, Aluminium hydroxide is approved for use as an adjuvant in numerous vaccines due to its ability to increase phagocytosis and spur immune responses.

Aluminium hydroxide also has approval for use in a wide array of cosmetic products at varying concentrations.
Aluminum hydroxide can also serve as a phosphate binder in patients with chronic renal disease.
However, Aluminium hydroxides use in this manner is infrequent due to the risk of adverse effects.
Commonly, oral aluminum hydroxide is a liquid formulation of both aluminum and magnesium hydroxide.

Mechanism of Action:
Aluminum hydroxide [Al(OH)3] dissociates into Al3+ and OH- in the stomach.
The freed hydroxide groups then bind to free protons, ultimately producing water and insoluble aluminum salts, mostly Al(Cl)3, within the stomach.
The proton binding serves to increase the overall pH of the stomach, i.e., less acidic, reducing the symptoms of indigestion.
The produced aluminum salt primarily gets excreted in the feces, with less than 1% of the bioavailable aluminum absorbed within the GI tract.

Aluminum exists at a steady-state within the body, so the body manages transient increases in aluminum uptake from use as an antacid with an equivalent increase in urinary excretion of unmodified aluminum.
However, the setpoint of that steady-state may become elevated with prolonged increased intake of aluminum, so aluminum hydroxide treatment should not be considered as a long-term solution for patients suffering from acid indigestion.
Furthermore, patients with chronic kidney disease may not be able to excrete the increased aluminum and thus also should be carefully considered.

Topical aluminum hydroxide creates an acidic, hydrophilic layer over the area of irritation; this serves as a protective barrier to prevent infection and deter bacterial growth within the wound.
As an adjuvant in vaccines, aluminum hydroxide is known to increase macrophage phagocytosis, possibly via the upregulation of the NLRP3-inflammasome, increasing uptake of the desired antigen.
Additionally, it is known to facilitate what is known as the "repository effect," whereby the antigens aggregate on and around the molecule, which helps to prevent their degradation within the body.

Administration:
Aluminum hydroxide when used as an antacid is to be delivered orally.
Shake the aluminum hydroxide suspension well before use.
Aluminium hydroxide should be taken 5 to 6 times daily after meals and at bedtime, not to exceed 3.84 g per 24 hours.
The patient should follow the dose with water intake.

Topical aluminum hydroxide should be applied to the desired area and left in place.
Topical aluminum has minimal skin absorption, so topical treatment with aluminum hydroxide may require reapplication as necessary.

The administration of aluminum hydroxide as an antacid should not be for prolonged management of patient symptoms.
Similarly, aluminum hydroxide should not be administered to patients with renal impairment.
In these instances, increased aluminum may precipitate more severe adverse effects or deplete the body's phosphate reserves.

Formula for Aluminum Hydroxide: H3AlO3
Properties for Aluminum Hydroxidee
Molar mass: 78.00 g/mol
Melting point: 300 °C (572 °F; 573 K)
Density: 2.42 g/cm3, solid

Production of Aluminium hydroxide:
Virtually all the aluminium hydroxide used commercially is manufactured by the Bayer process which involves dissolving bauxite in sodium hydroxide at temperatures up to 270 °C (518 °F).
The waste solid, bauxite tailings, is removed and aluminium hydroxide is precipitated from the remaining solution of sodium aluminate.
This aluminium hydroxide can be converted to aluminium oxide or alumina by calcination.

The residue or bauxite tailings, which is mostly iron oxide, is highly caustic due to residual sodium hydroxide.
Aluminium hydroxide was historically stored in lagoons; this led to the Ajka alumina plant accident in 2010 in Hungary, where a dam bursting led to the drowning of nine people.
An additional 122 sought treatment for chemical burns.
The mud contaminated 40 square kilometres (15 sq mi) of land and reached the Danube.
While the mud was considered non-toxic due to low levels of heavy metals, the associated slurry had a pH of 13.

Why is Aluminium hydroxide prescribed?
Aluminum Hydroxide, Magnesium Hydroxide are antacids used together to relieve heartburn, acid indigestion, and upset stomach.
Aluminium hydroxide may be used to treat these symptoms in patients with peptic ulcer, gastritis, esophagitis, hiatal hernia, or too much acid in the stomach (gastric hyperacidity).
Aluminium hydroxide combine with stomach acid and neutralize it.
Aluminum Hydroxide, Magnesium Hydroxide are available without a prescription.

Aluminium hydroxide is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

What is aluminum hydroxide?
Aluminum is a naturally occurring mineral. Aluminum hydroxide is an antacid.
Aluminum hydroxide is used to treat heartburn, upset stomach, sour stomach, or acid indigestion.
Aluminum hydroxide is also used to reduce phosphate levels in people with certain kidney conditions.
Aluminum hydroxide may also be used for purposes not listed in this medication guide.

Formula: AlH3O3 / Al(OH)3
Molecular mass: 78.0
Melting point: 300°C
Density: 2.42 g/cm³
Solubility in water: none
Vapour pressure, Pa at 20°C:
Aluminium hydroxide Benefits:
-High performance coagulant based on aluminium hydroxide chloride
-Excellent turbidity / suspended solids removal
-Automatic buffering effect reduces pH depression
-High cationic charge density
-Very low sludge volume
-Reduce your chemical dose and treatment costs

How should Aluminium hydroxide be used?
This medication comes as a chewable tablet and liquid to take by mouth.
Chew tablets thoroughly; do not swallow them whole.
Drink a full glass of water after taking the tablets.
Shake the oral liquid well before each use to mix the medicine evenly.
The liquid may be mixed with water or milk.

Follow the directions on the package label or on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
Take Aluminum Hydroxide, Magnesium Hydroxide antacids exactly as directed.
Do not take more or less of Aluminium hydroxide or take it more often than prescribed by your doctor.
Do not take antacids for more than 1 to 2 weeks unless prescribed by your doctor.

What special precautions should I follow?
Before taking Aluminum Hydroxide, Magnesium Hydroxide antacids,
tell your doctor and pharmacist if you are allergic to Aluminum Hydroxide, Magnesium Hydroxide antacids or any other drugs.
tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially aspirin, cinoxacin (Cinobac), ciprofloxacin (Cipro), digoxin (Lanoxin), diazepam (Valium), enoxacin (Penetrex), ferrous sulfate (iron), fluconazole (Diflucan), indomethacin, isoniazid (INH), itraconazole (Sporanox), ketoconazole (Nizoral), levofloxacin (Levaquin), lomefloxacin (Maxaquin), nalidixic acid (NegGram), norfloxacin (Noroxin), ofloxacin (Floxin), sparfloxacin (Zagam), tetracycline (Achromycin, Sumycin), and vitamins. If your doctor tells you to take antacids while taking these medications, do not take them within 2 hours of taking an antacid.
tell your doctor if you have or have ever had kidney disease.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding.
If you become pregnant while taking Aluminum Hydroxide, Magnesium Hydroxide antacids, call your doctor.

What special dietary instructions should I follow?
If you are taking this medication for an ulcer, follow the diet prescribed by your doctor carefully.

What should I do if I forget a dose?
If you are taking scheduled doses of Aluminum Hydroxide, Magnesium Hydroxide, take the missed dose as soon as you remember it.
However, if Aluminium hydroxide is almost time for the next dose, skip the missed dose and continue your regular dosing schedule.
Do not take a double dose to make up for a missed one.

aluminum;trihydroxide
Dried aluminum hydroxide gel
Aluminium hydroxide gel, dried
aluminium trihydroxide
aluminum hyroxide
Hydroxyde d' aluminium
Dried aluminium hydroxide
Aluminium hydroxide, dried
Aluminum hydroxide gel, dried
CHEMBL1200706
DTXSID2036405
NIOSH/BD070800
Di-mu-hydroxytetrahydroxydialuminum
Aluminum Hydroxide, Technical Grade
AF-260
AKOS015904617
Aluminum, di-mu-hydroxytetrahydroxydi-
DB06723
BD07080000
Q407125
J-014205
UNII-F41V936QZM component WNROFYMDJYEPJX-UHFFFAOYSA-K
Aluminium hydroxide [Wiki] [REDIRECT]
14762-49-3 [RN]
21645-51-2 [RN]
244-492-7 [EINECS]
5QB0T2IUN0
Aluminium trihydroxide [ACD/IUPAC Name]
aluminium(3+) hydroxide
aluminium(III) hydroxide
Aluminiumtrihydroxid [German] [ACD/IUPAC Name]
ALUMINUM HYDROXIDE [USP]
Aluminum trihydroxide
Aluminum(III) hydroxide
GIBBSITE
Trihydroxyaluminum
Trihydroxyde d'aluminium [French] [ACD/IUPAC Name]
1330-44-5 [RN]
135151-77-8 [RN]
13765-93-0 [RN]
150828-31-2 [RN]
24623-77-6 [RN]
36201-72-6 [RN]
37324-42-8 [RN]
51668-55-4 [RN]
52350-11-5 [RN]
7784-30-7 [RN]
8022-59-1 [RN]
89686-54-4 [RN]
93237-81-1 [RN]
ALternaGEL
AlternaGel (Trade name)
AlternaGel; Alu-Cap; Amphojel
Alu-Cap
Alu-Cap (Trade name)
aluminium (III) hydroxide
Aluminium hydroxide gel, dried
Aluminium hydroxide, dried
Aluminium hydroxide; Aluminium hydroxide gel, dried; Aluminium hydroxide, dried; Aluminum hydroxide gel, dried; Aluminum hydroxide, dried; Dried aluminium hydroxide; Dried aluminum hydroxide gel
Aluminium tri-hydroxide
aluminium(3+) ion trihydroxide
aluminium(3+) ion trioxidanide
ALUMINIUM(3+) TRIHYDROXIDE
aluminiumhydroxide
Aluminum (III) Hydroxide (reagent)
aluminum and trihydroxide
Aluminum hydroxide gel, dried
Aluminum hydroxide, dried [JAN]
Aluphos
Amphojel
BASIC ALUMINUM HYDROXIDE
Dried aluminium hydroxide
Dried aluminum hydroxide gel
EINECS 232-056-9
hydroxide aluminium
MFCD00003420
UNII:5QB0T2IUN0
UNII-5QB0T2IUN0
UNII-F41V936QZM
氢氧化铝 [Chinese]
ALUMINIUM MONOSTEARATE
Aluminium Monostearate Aluminium monostearate is an organic compound which is a salt of stearic acid and aluminium. It has the molecular formula Al(OH)2C18H35O2. It is also referred to as dihydroxy(octadecanoato-O-)aluminium or dihydroxy(stearato)aluminium. Aluminium monostearate is used to form gels in the packaging of pharmaceuticals, and in the preparation of colors for cosmetics. It is usually safe in commercial products, but aluminium may accumulate in the body. Properties of Aluminium Monostearate Chemical formula C18H37AlO4 Molar mass 344.472 g·mol−1 Antacids perform a neutralization reaction, ie. they buffer gastric acid, raising the pH to reduce acidity in the stomach. When gastric hydrochloric acid reaches the nerves in the gasitrointestinal mucosa, they signal pain to the central nervous system. This happens when these nerves are exposed, as in peptic ulcers. The gastric acid may also reach ulcers in the esophagus or the duodenum. Other mechanisms may contribute, such as the effect of aluminum ions inhibiting smooth muscle cell contraction and delaying gastric emptying. Aluminum is known to bind troponin C (a muscle protein) and to interfere with voltage-dependent calcium transport. Aluminum also binds to and inhibits the activity of mitochondrial voltage gated channels (VDAC). Description of Aluminium Monostearate Aluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2. Also known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging of pharmaceuticals and in the preparation of colors for cosmetics. While considered safe for use, extensive usage may result in aluminum accumulation. Aluminium Stearate (C54H105AlO6) exists as white powder and is an aluminum salt of stearic acid. In the pharmaceutical industry, it is used as an anticaking agent; colorant; emulsion stabilizer; and viscosity increasing agent. According to the FDA, aluminum stearate is considered safe for general or specific, limited use in food. Aluminium stearate is not classifiable as a human carcinogen (cancer-causing agent). Description of Aluminium Monostearate Aluminium monostearate is a salt of stearic acid and aluminium. It is used to form gels in the packaging of pharmaceuticals, and in the preparation of colors for cosmetics. Aluminum is the most abundant metal in the earth's crust and is always found combined with other elements such as oxygen, silicon, and fluorine. (5, 6, 7) What is Aluminium Monostearate? Aluminium monostearate (C54H105AlO6) exists as white powder and is an aluminum salt of stearic acid. In the pharmaceutical industry, it is used as an anticaking agent; colorant; emulsion stabilizer; and viscosity increasing agent. According to the FDA, Aluminium monostearate is considered safe for general or specific, limited use in food. Aluminium monostearate is not classifiable as a human carcinogen (cancer-causing agent). Compound Type Aluminum Compound Household Toxin Industrial/Workplace Toxin Organic Compound Organometallic Synthetic Compound Uses of Aluminium Monostearate Aluminium monostearate is used to form gels in the packaging of pharmaceuticals, and in the preparation of colors for cosmetics. Use: Aluminium Monostearate is one of numerous organo-metallic compounds sold by American Elements under the tradename AE Organo-Metallics™ for uses requiring non-aqueous solubility such as recent solar energy and water treatment applications. Similar results can sometimes also be achieved with Nanoparticles (also see Nanotechnology and Quantum Dots) and by thin film deposition. Note American Elements additionally supplies many materials as solutions. Aluminum Monostearate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. Additional technical, research and safety information is available. Use: Aluminium Monostearate can be used in the preparation of colors for cosmetics and for the packaging of pharmaceuticals. Aluminium monostearate is the aluminum salt of the fatty acid, stearic acid. Aluminium Monostearate The Stearate salts, including Lithium Stearate, Aluminum Distearate, Aluminium monostearate, Aluminum Tristearate, Ammonium Stearate, Calcium Stearate, Magnesium Stearate, Potassium Stearate, Sodium Stearate, and Zinc Stearate are fine, white powders with a slight fatty odor. In cosmetics and personal care products, Stearate salts are used mainly in the formulation of makeup products such as eyeliner, eyeshadow, mascara, lipsticks, blushers, face powders and foundations. They are also used in fragrances, deodorants, and hair and skin care products. Why is Aluminium Monostearate used in cosmetics and personal care products? The Stearate salts are generally used for their lubricating properties. They also help to keep emulsions from separating into their oil and liquid components. The Stearate salts increase the thickness of the lipid (oil) portion of cosmetics and personal care products and reduce the clear or transparent appearance of finished products. Scientific Facts of Aluminium Monostearate: The commercial stearic acid from which the Stearate salts are manufactured is actually a mixture of monocarboxylic acids obtained from animal and/or vegetable sources. Aluminium monostearate is an organic compound which is a salt of stearic acid and aluminium. It has the molecular formula Al(OH)2C18H35O2. It is also referred to as dihydroxy(octadecanoato-O-)aluminium or dihydroxy(stearato)aluminium. It is used to form gels in the packaging of pharmaceuticals, and in the preparation of colors for cosmetics. It is usually safe in commercial products, but aluminium may accumulate in the body. Aluminium monostearate (aluminum distearate) is a white, wax-like powder (metallic soap) that dissolves in mineral spirits or hot oil. A small amount (2% or less) added to oil paint imparts a short, buttery consistency. It eliminates the separation of pigment and oil, thickens varnishes considerably. A concentrate of Aluminium monostearate and linseed oil can be prepared ahead of time and added to the paint whenever needed. Aluminium monostearate is made via the precipitation process using high quality stearic acid and exhibits the following properties: Good gelling and thickening action, excellent water repellency, transparency and a synergistic effect with zinc stearate or calcium stearate. The effects of metal soaps on pigments have been extensively studied. Aluminium monostearate was found to coat the surface of pigment particles and helped prevent settling as well as reducing the amount of oil needed to wet the pigment. The amount of Aluminium monostearate needed to coat pigments varied on a weight basis, but a solution of 2% by weight (weight of Aluminium monostearate/weight of oil) of Aluminium monostearate was more effective than 0.5% or 4% solutions in altering pigment surfaces (Gardner 1930). The soaps coat the surface of the pigments and by steric effects keep the particles from aggregating (Pilpel 1963), which helps to keep the particles in suspension. With increasing amounts of Aluminium monostearate the oil pigment mixture becomes viscous, and by using an appropriate amount of Aluminium monostearate the paint can gel at a lower pigment concentration (Mayer 1965). This can be used to create a "cheaper" paint since a smaller amount of a costly pigment needs to be used. A significant advantage of using stearates is that the oil and pigment do not separate greatly over long periods of time in the paint tube. Manufacturers of artists' paints often use Aluminium monostearate in their formulations without listing it as a component on the product label. Substituents of Aluminium monostearate Carboxylic acid salt Organic metal salt Monocarboxylic acid or derivatives Organic oxygen compound Organic oxide Hydrocarbon derivative Organic salt Organooxygen compound Carbonyl group Aliphatic acyclic compound Solubility of Aluminium monostearate Aluminium monostearate exhibits relatively high solubility in hydrocarbon solvents (such as mineral spirits) when compared to other metallic stearates. It is insoluble in water, alcohol and ether; but is readily soluble in benzene, acids and common solvents when hot. Storage of Aluminium monostearate Aluminium monostearate has long storage life if stored in cool and dry location. Uses of Aluminium monostearate It has been used as a Drier, thickener, Emulsifier, and matting agent in paints and varnishes although excess amounts produce soft, noncohesive films. Aluminium monostearate is also used to waterproof fabrics, ropes, Paper, Leather, Concrete, and Stucco. It is used as an ingredient in photographic emulsions. Aluminium monostearate dissolves in vegetable oils on heating and if a high enough concentration of the soap is used, gelling occurs on cooling. In the usual practice of making paints, the Aluminium monostearate is ground with the pigment before the bulk of the oil is added. To prepare a concentrated solution (10% w/v), add 100 grams of Aluminium monostearate (nearly fills a half liter measuring cup without compacting) to one liter of linseed oil. Heat the oil to about 150° C. and gradually slowly adding the white powder to the hot oil with stirring. Add one part of this solution to four parts of oil by weight of oil before adding to pigments and grinding. There are multiple types of Aluminium monostearates, generally classified as aluminum mono-, di-, and tri-stearate. They vary in terms of physical properties such as melting point, free fatty acids, and particularly the gelling properties. Oils with a low viscosity are best thickened by aluminum di- and tri-stearate, whilst very viscous oils from stiffer gel when combined with aluminum mono- or di-stearates. All Aluminium monostearates are highly hydrophobic, and feature outstanding transparency and excellent adhesion to metal surfaces. Due to their water repellency, aluminum di- and tri-stearate are used as hydrophobic agents in the building industry. Aluminium monostearate (aluminum distearate) is a white, wax-like powder (metallic soap) that dissolves in mineral spirits or hot oil. A small amount (2% or less) added to oil paint imparts a short, buttery consistency. It eliminates the separation of pigment and oil, thickens varnishes considerably. A concentrate of Aluminium monostearate and linseed oil can be prepared ahead of time and added to the paint whenever needed. Aluminium monostearate is made via the precipitation process using high quality stearic acid and exhibits the following properties: Good gelling and thickening action, excellent water repellency, transparency and a synergistic effect with zinc stearate or calcium stearate. The effects of metal soaps on pigments have been extensively studied. Aluminium monostearate was found to coat the surface of pigment particles and helped prevent settling as well as reducing the amount of oil needed to wet the pigment. The amount of Aluminium monostearate needed to coat pigments varied on a weight basis, but a solution of 2% by weight (weight of Aluminium monostearate/weight of oil) of Aluminium monostearate was more effective than 0.5% or 4% solutions in altering pigment surfaces (Gardner 1930). The soaps coat the surface of the pigments and by steric effects keep the particles from aggregating (Pilpel 1963), which helps to keep the particles in suspension. With increasing amounts of Aluminium monostearate the oil pigment mixture becomes viscous, and by using an appropriate amount of Aluminium monostearate the paint can gel at a lower pigment concentration (Mayer 1965). This can be used to create a "cheaper" paint since a smaller amount of a costly pigment needs to be used. A significant advantage of using stearates is that the oil and pigment do not separate greatly over long periods of time in the paint tube. Manufacturers of artists' paints often use Aluminium monostearate in their formulations without listing it as a component on the product label. Aluminium monostearate exhibits relatively high solubility in hydrocarbon solvents (such as mineral spirits) when compared to other metallic stearates. It is insoluble in water, alcohol and ether; but is readily soluble in benzene, acids and common solvents when hot. How to Use Aluminium monostearate Aluminium monostearate dissolves in vegetable oils on heating and if a high enough concentration of the soap is used, gelling occurs on cooling. In the usual practice of making paints, the Aluminium monostearate is ground with the pigment before the bulk of the oil is added. To prepare a concentrated solution (10% w/v), add 100 grams of Aluminium monostearate (nearly fills a half liter measuring cup without compacting) to one liter of linseed oil. Heat the oil to about 150° C. and gradually slowly adding the white powder to the hot oil with stirring. Add one part of this solution to four parts of oil by weight of oil before adding to pigments and grinding. Aluminium monostearate (C54H105AlO6) exists as white powder and is an aluminum salt of stearic acid. In the pharmaceutical industry, it is used as an anticaking agent; colorant; emulsion stabilizer; and viscosity increasing agent. According to the FDA, Aluminium monostearate is considered safe for general or specific, limited use in food. Aluminium monostearate is not classifiable as a human carcinogen (cancer-causing agent). A hard, thermoplastic white powder prepared from Tallow and Alum. Aluminium monostearate forms gels with turpentine, Mineral spirits, and oils. It has been used as a Drier, thickener, Emulsifier, and matting agent in paints and varnishes although excess amounts produce soft, noncohesive films. Aluminium monostearate is also used to waterproof fabrics, ropes, Paper, Leather, Concrete, and Stucco. It is used as an ingredient in photographic emulsions. Synonyms and Related Terms aluminum tristearate; octadecanoic acid aluminum salt; stearic acid aluminum salt; Aluminium monostearate white (AAT); stéarate d'aluminium (Fr.); Daiwax WA1; Metaspa XX; Rofob 3 Other Properties Soluble in ethanol, benzene, turpentine and mineral oils. When Aluminium monostearate was first introduced to artists' paints specifically is not known, but it is directly mentioned in a 1942 painting materials review (Gettens and Stout 1942) and in a paper by Levison in 1949 when he wrote " ... the use of Aluminium monostearate, customary for several decades, was openly declared, .." (Levison 1949 p. 826). He also notes that this soap can be added in quantities up to 2% of the grind without perceptible dilution of pigment color. Unlike calcium and zinc stearates that are available as 100% pure salts, the Aluminium monostearate as used in commerce is a non-stoichiometric compound. The trivalent aluminum may be united with one or two stearate anions with the balance of the charge being neutralized by hydroxyl anions (Elliott 1946; Pilpel 1971). Aqueous systems for the preparation or use of disalts seems to lead to a range of products containing varying amounts of stearate, hydroxyl, and water units (Pilpel 1963). Anhydrous systems are needed to prepare stearates higher than the di-salt. Commercial preparations of Aluminium monostearate may also contain anywhere from 2 to 7% by weight free stearic acid (Pilpel 1971; Witco 1999). Analysis by weight of two commercial specimens by the author showed free stearic acid as 2 and 3% respectively. Early preparations may also contain significant amounts of palmitate (from palmitic acid) since the commercial stearic acid used in the preparation of metal soaps was often only 90% pure. Other fatty acids (palmitic, oleic, linoleic etc.) were also present as impurities. Aluminium monostearate dissolves in vegetable oils on heating and if a high enough concentration of the soap is used, gelling occurs on cooling. In the usual practice of making paints, the Aluminium monostearate is ground with the pigment before the bulk of the oil is added. In a series of experiments Gardner tested the effects of metal soaps on pigments. Aluminium monostearate was found to coat the surface of pigment particles and helped prevent settling as well as reducing the amount of oil needed to wet the pigment. The amount of Aluminium monostearate needed to coat pigments varied on a weight basis, but a solution of 2% by weight (wt stearate/wt oil) Aluminium monostearate was more effective than 0.5% or 4% solutions in altering the surface (Gardner 1930). The soaps coat the surface of the pigments and by steric effects or electrical charge mechanisms keep the particles from aggregating (Pilpel 1966). This keeps the pigments in suspension. With increasing amounts of Aluminium monostearate the oil pigment mixture becomes viscous, and by using an appropriate amount of Aluminium monostearate the paint can gel at a lower pigment concentration (Mayer 1965). This can be used to create a "cheaper" paint since a smaller amount of a costly pigment needs to be used. A significant advantage of using stearates is that the oil and pigment do not separate greatly over long periods of time in the paint tube. The earliest and simplest oil paints were mixtures of pigments and drying oils. Eventually driers, resins, fillers, sometimes adulterants and suspension aids were also added. Aluminium monostearate was one of the components introduced in the 20th century. The gelling of oil solutions by aluminum soaps was known since at least the late 19th century but the use of Aluminium monostearate to alter the properties of paint did not come into use until much later. Church in 1901 mentions the use of "linoleate or oleate of alumina" to prevent the "subsidence" of vermilion in tubes (Church 1901), a comment not found in the 1890 edition (Church 1890). No further mention is made of this or similar materials until decades later even in Gardner's test protocols of 1911, the first of a series of books which would become the industry standard for paint analysis (Gardner 1911). Aluminium monostearate has been used to help suspend pigments in oil to prevent separation, to reduce the amount of oil needed to wet the pigment, and/or to increase the body of the paint by forming a gel with the oil thereby requiring less pigment. Research into the use of aluminum and zinc stearates as aids to grinding pigments and preventing settling or separation of pigment from vehicle (medium) resulted in a patent application in 1920 and issue of U.S. patent #1,421, 625 on July 23, 1922 to Clarence A. Ward. The Aluminium monostearate was added in a range of from 1 to 5% by weight. U.S. patent #1,428,273 describing a variation of this procedure but using unsaturated mineral oils as a vehicle and aluminum soaps (stearate, palmitate etc.) to "jellify" the oil was issued on September 5, 1922 to W. A. Collings. A 1923 commercial painters manual, however, does not list these soaps (Kelly 1923), but by 1927 the fourth edition of Gardner's paint testing manual states: "Aluminium monostearate has been used in considerable quantities during recent years, in the paint and varnish industries." (Gardner 1927, p. 664). A British test manual of 1927, however, fails to mention Aluminium monostearate or its class of materials (Fox and Bowles 1927). So at least by the early to mid 1920's Aluminium monostearate was available for commercial use and by implication use in artists' paints. In regard to the wetting of pigments, the small amounts of free fatty acids normally present in pressed oils helped form soaps at the pigment interface, aided dispersion, and improved settling characteristics. Alkali refined linseed with its low free acid content created settling problems which were mediated by pigments precoated with metal soaps. Aluminium monostearate is one of numerous organo-metallic compounds sold by American Elements under the trade name AE Organo-Metallics™ for uses requiring non-aqueous solubility such as recent solar energy and water treatment applications. Similar results can sometimes also be achieved with Nanoparticles and by thin film deposition. Note American Elements additionally supplies many materials as solutions. Aluminium monostearate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. Additional technical, research and safety information is available. Aluminium monostearate is a fine, bulky, odourless and colourless powder forming a plastic mass when heated, having the properties both of organic and inorganic matter. It embraces most of the characteristics of other metallic stearates and is regarded as the most important of these. Several studies of the material have already appeared in past years. Description A hard, thermoplastic white powder prepared from Tallow and Alum. Aluminium monostearate forms gels with turpentine, Mineral spirits, and oils. It has been used as a Drier, thickener, Emulsifier, and matting agent in paints and varnishes although excess amounts produce soft, noncohesive films. Aluminium monostearate is also used to waterproof fabrics, ropes, Paper, Leather, Concrete, and Stucco. It is used as an ingredient in photographic emulsions. Aluminium monostearate is a white, wax-like powder (metallic soap) that dissolves in mineral spirits or hot oil. A small amount (2% or less) added to oil paint imparts a short, buttery consistency. It eliminates the separation of pigment and oil, thickens varnishes considerably. A concentrate of Aluminium monostearate and linseed oil can be prepared ahead of time and added to the paint whenever needed. Aluminium monostearate is made via the precipitation process using high quality stearic acid and exhibits the following properties: Good gelling and thickening action, excellent water repellency, transparency and a synergistic effect with zinc stearate or calcium stearate. The effects of metal soaps on pigments have been extensively studied. Aluminium monostearate was found to coat the surface of pigment particles and helped prevent settling as well as reducing the amount of oil needed to wet the pigment. The amount of Aluminium monostearate needed to coat pigments varied on a weight basis, but a solution of 2% by weight (weight of Aluminium monostearate/weight of oil) of Aluminium monostearate was more effective than 0.5% or 4% solutions in altering pigment surfaces (Gardner 1930). The soaps coat the surface of the pigments and by steric effects keep the particles from aggregating (Pilpel 1963), which helps to keep the particles in suspension. With increasing amounts of Aluminium monostearate the oil pigment mixture becomes viscous, and by using an appropriate amount of Aluminium monostearate the paint can gel at a lower pigment concentration (Mayer 1965). This can be used to create a "cheaper" paint since a smaller amount of a costly pigment needs to be used. A significant advantage of using stearates is that the oil and pigment do not separate greatly over long periods of time in the paint tube. Manufacturers of artists' paints often use Aluminium monostearate in their formulations without listing it as a component on the product label. Aluminium monostearate exhibits relatively high solubility in hydrocarbon solvents (such as mineral spirits) when compared to other metallic stearates. It is insoluble in water, alcohol and ether; but is readily soluble in benzene, acids and common solvents when hot. Aluminium monostearate has long storage life if stored in cool and dry location. How to use aluminium monostearate Aluminium monostearate dissolves in vegetable oils on heating and if a high enough concentration of the soap is used, gelling occurs on cooling. In the usual practice of making paints, the Aluminium monostearate is ground with the pigment before the bulk of the oil is added. To prepare a concentrated solution (10% w/v), add 100 grams of Aluminium monostearate (nearly fills a half liter measuring cup without compacting) to one liter of linseed oil. Heat the oil to about 150° C. and gradually slowly adding the white powder to the hot oil with stirring. Add one part of this solution to four parts of oil by weight of oil before adding to pigments and grinding.
ALUMINIUM NON LEAFING PASTE -4NL
Aluminum oxide basic; Alumina trihydrate; Alumina acidic; Alumina; Corundum; Saphire; Ruby; Alumina basic; Alumina hydrate; Alumina neutral; Alumina trihydrate; Alumininum oxide; Aluminium oxide; Tabular alumina; Aluminiumoxid; óxido de aluminio; Oxyde d'aluminium; morin dyed; Alundum; Boileezers CAS NO:1344-28-1 (Al2O3), 11092-32-3 (AlO2)
ALUMINIUM OXIDE
Aluminum Silicate; Silicic acid, aluminum salt; Aluminosilicic acid; Kieselsäure, Aluminiumsalz; ácido silícico, sal de aluminio; Acide silicique, sel d'aluminium; China clay; Kaolinite; Kaopectate; Porcelain clay; Aluminosilicic acid; Natural Aluminum Silicate; ALUMINIUMSILICATE,HYDRATE; Silicic acid, aluminum salt CAS NO:1335-30-4
ALUMINIUM OXIDE
DESCRIPTION:
Aluminium oxide (or Aluminium(III) oxide) is a chemical compound of aluminium and oxygen with the chemical formula Al2O3.
Aluminium oxide is the most commonly occurring of several aluminium oxides, and specifically identified as aluminium oxide.
Aluminium oxide is commonly called alumina and may also be called aloxide, aloxite, or alundum in various forms and applications.

CAS Number: 1344-28-1
EC Number: 215-691-6
IUPAC name: Aluminium oxide

CHEMICAL AND PHYSICAL OF PROPERTIES ALUMINIUM OXIDE:
Chemical formula: Al2O3
Molar mass: 101.960 g•mol−1
Appearance: white solid
Odor: odorless
Density: 3.987 g/cm3
Melting point: 2,072 °C (3,762 °F; 2,345 K)[3]
Boiling point: 2,977 °C (5,391 °F; 3,250 K)[4]
Solubility in water: insoluble
Solubility: insoluble in all solvents
log P: 0.31860[1]
Magnetic susceptibility (χ): −37.0×10−6 cm3/mol
Thermal conductivity: 30 W•m−1•K−1[2]
Refractive index (nD): nω=1.768–1.772
nε=1.760–1.763
Birefringence: 0.008
Structure:
Crystal structure: Trigonal, hR30
Space group: R3c (No. 167)
Lattice constant:
a = 478.5 pm, c = 1299.1 pm
Coordination geometry octahedral
Thermochemistry:
Std molar entropy (S⦵298): 50.92 J•mol−1•K−1[5]
Std enthalpy of formation (ΔfH⦵298): −1675.7 kJ/mol
Molecular Weight: 101.961
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 0
Exact Mass: 101.947821
Monoisotopic Mass: 101.947821
Topological Polar Surface Area: 3 Ų
Heavy Atom Count: 5
Formal Charge: 0
Complexity: 0
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 5
Compound Is Canonicalized: Yes

CHEMICAL PROPERTIES OF ALUMINIUM OXIDE:
1. Reaction with sodium hydroxide:
Aluminium oxide reacts with sodium hydroxide to produce sodium aluminate and water.
This reaction takes place at a temperature of 900-1100°C.
Salt and water are obtained in this reaction in which aluminium oxide acts as an acid.
Al2O3 + 2NaOH → 2NaAlO2 + H2O

2. Reaction with sulphuric acid:
Metal oxides are generally basic in nature but aluminium oxide is amphoteric oxide.
Hence Aluminium oxide acts both as acid and base.
In this case, Aluminium oxide acts as a base
Al2O3 + H2SO4 → Al2(SO4)3 + H2O
This is a neutralisation reaction.

3. Reaction with hydrochloric acid
Aluminium oxide contains oxide ions, and thus reacts with acids in the same way sodium or magnesium oxides do.
Aluminium oxide reacts with hot dilute hydrochloric acid to give aluminium chloride solution.
Al2O3+6HCl → 2AlCl3+3H2O
Aluminium oxide (British English) or aluminum oxide (American English) is a chemical compound of aluminium and oxygen with the chemical formula Al2O3.

GENERAL INFORMATION ABOUT ALUMINIUM OXIDE:
Aluminium oxide is the most commonly occurring of several aluminium oxides, and specifically identified as aluminium(III) oxide.
Aluminium oxide is commonly called alumina, and may also be called aloxide, aloxite, or alundum depending on particular forms or applications.
Aluminium oxide occurs naturally in its crystalline polymorphic phase α-Al2O3 as the mineral corundum, varieties of which form the precious gemstones ruby and sapphire.

Al2O3 is significant in its use to produce aluminium metal, as an abrasive owing to its hardness, and as a refractory material owing to its high melting point.

Over 90% of the aluminium oxide, normally termed Smelter Grade Alumina (SGA), produced is consumed for the production of aluminium, usually by the Hall–Héroult process.
The remainder, normally called speciality alumina is used in a wide variety of applications which reflect its inertness, temperature resistance and electrical resistance.

Being fairly chemically inert and white, aluminium oxide is a favored filler for plastics.
Aluminium oxide is a common ingredient in sunscreen and is sometimes also present in cosmetics such as blush, lipstick, and nail polish.
Many formulations of glass have aluminium oxide as an ingredient.

Aluminium oxide catalyses a variety of reactions that are useful industrially.
In its largest scale application, aluminium oxide is the catalyst in the Claus process for converting hydrogen sulfide waste gases into elemental sulfur in refineries.
Aluminium oxide is also useful for dehydration of alcohols to alkenes.
Aluminium oxide serves as a catalyst support for many industrial catalysts, such as those used in hydrodesulfurization and some Ziegler-Natta polymerizations.

Aluminium oxide is widely used to remove water from gas streams.
Aluminium oxide is used for its hardness and strength.
Aluminium oxide is widely used as an abrasive, including as a much less expensive substitute for industrial diamond.

Many types of sandpaper use aluminium oxide crystals.
In addition, its low heat retention and low specific heat make Aluminium oxide widely used in grinding operations, particularly cutoff tools.
As the powdery abrasive mineral aloxite, it is a major component, along with silica, of the cue tip "chalk" used in billiards.

Aluminium oxide powder is used in some CD/DVD polishing and scratch-repair kits.
Its polishing qualities are also behind its use in toothpaste.
Aluminium oxide flakes are used in paint for reflective decorative effects, such as in the automotive or cosmetic industries.

Aluminium oxide has been used in a few experimental and commercial fiber materials for high-performance applications (e.g., Fiber FP, Nextel 610, Nextel 720).
Alumina nanofibers in particular have become a research field of interest.
Aluminium oxide can be grown as a coating on aluminium by anodizing or by plasma electrolytic oxidation (see the "Properties" above).
Both the hardness and abrasion-resistant characteristics of the coating originate from the high strength of aluminium oxide, yet the porous coating layer produced with conventional direct current anodizing procedures is within a 60-70 Rockwell hardness C range which is comparable only to hardened carbon steel alloys, but considerably inferior to the hardness of natural and synthetic corundum.
Instead, with plasma electrolytic oxidation, the coating is porous only on the surface oxide layer while the lower oxide layers are much more compact than with standard DC anodizing procedures and present a higher crystallinity due to the oxide layers being remelted and densified to obtain α-Al2O3 clusters with much higher coating hardness values circa 2000 Vickers hardness.

Alumina is used to manufacture tiles which are attached inside pulverized fuel lines and flue gas ducting on coal fired power stations to protect high wear areas.
They are not suitable for areas with high impact forces as these tiles are brittle and susceptible to breakage.

USES OF ALUMINIUM OXIDE (AL2O3):
Aluminium oxide is one of the common ingredients in sunscreen and is also present in cosmetics such as nail polish, blush, and lipstick.
Aluminium oxide is used in formulations of glass.
Aluminium oxide is used as a catalyst.
Aluminium oxide is used in the purification of water to remove water from the gas streams.

Aluminium oxide is used in sandpaper as an abrasive.
Aluminium oxide is an electrical insulator used as a substrate for integrated circuits.
Aluminium oxide is Used in sodium vapour lamps.
Aluminum oxide is one of most used raw material in the world.

Aluminum oxide can be provided with different grain sizes and purity.
Aluminum oxide is mostly used in ceramic, frit, glass, refractory and abrasive sectors.
Aluminum oxide improves the chemical stability, refractoriness, thermal shock resistance, wear resistance at the places where it is used. Resistance to oxidative and reductive atmospheres is high.

Aluminum oxide is a white odorless crystalline powder.
Aluminum oxide is Water insoluble.
Properties (both physical and chemical) vary according to the method of preparation; different methods give different crystalline modifications.
The variety formed at very high temperature is quite inert chemically.
alpha-Alumina is the main component of technical grade alumina.

Corundum is natural aluminum oxide.
Emery is an impure crystalline variety of aluminum oxide. (NIOSH, 2022)
Aluminum oxide has a chemical formula Al2O3.
Aluminum oxide is amphoteric in nature, and is used in various chemical, industrial and commercial applications.

Aluminum oxide is considered an indirect additive used in food contact substances by the FDA.
An oxide of aluminum, occurring in nature as various minerals such as bauxite, corundum, etc.
Aluminum oxide is used as an adsorbent, desiccating agent, and catalyst, and in the manufacture of dental cements and refractories.

NATURAL OCCURRENCE:
Corundum is the most common naturally occurring crystalline form of aluminium oxide.
Rubies and sapphires are gem-quality forms of corundum, which owe their characteristic colours to trace impurities.
Rubies are given their characteristic deep red colour and their laser qualities by traces of chromium. Sapphires come in different colours given by various other impurities, such as iron and titanium.
An extremely rare δ form occurs as the mineral deltalumite.

Aluminium oxide occurs naturally in its crystalline polymorphic phase α-Al2O3 as the mineral corundum, varieties of which form the precious gemstones ruby and sapphire.
Al2O3 is significant in its use to produce aluminium metal, as an abrasive owing to its hardness, and as a refractory material owing to its high melting point.

PROPERTIES OF ALUMINIUM OXIDE:
Al2O3 is an electrical insulator but has a relatively high thermal conductivity (30 Wm−1K−1) for a ceramic material.
Aluminium oxide is insoluble in water.
In its most commonly occurring crystalline form, called corundum or α-aluminium oxide, its hardness makes Aluminium oxide suitable for use as an abrasive and as a component in cutting tools.

Aluminium oxide is responsible for the resistance of metallic aluminium to weathering.
Metallic aluminium is very reactive with atmospheric oxygen, and a thin passivation layer of aluminium oxide (4 nm thickness) forms on any exposed aluminium surface in a matter of hundreds of picoseconds.
This layer protects the metal from further oxidation.

The thickness and properties of this oxide layer can be enhanced using a process called anodising.
A number of alloys, such as aluminium bronzes, exploit this property by including a proportion of aluminium in the alloy to enhance corrosion resistance.

The aluminium oxide generated by anodising is typically amorphous, but discharge assisted oxidation processes such as plasma electrolytic oxidation result in a significant proportion of crystalline aluminium oxide in the coating, enhancing its hardness.
Aluminium oxide was taken off the United States Environmental Protection Agency's chemicals lists in 1988.
Aluminium oxide is on the EPA's Toxics Release Inventory list if it is a fibrous form.

Amphoteric nature:
Aluminium oxide is an amphoteric substance, meaning it can react with both acids and bases, such as hydrofluoric acid and sodium hydroxide, acting as an acid with a base and a base with an acid, neutralising the other and producing a salt.
Al2O3 + 6 HF → 2 AlF3 + 3 H2O
Al2O3 + 2 NaOH + 3 H2O → 2 NaAl(OH)4 (sodium aluminate)

STRUCTURE OF ALUMINIUM OXIDE:
The most common form of crystalline aluminium oxide is known as corundum, which is the thermodynamically stable form.
The oxygen ions form a nearly hexagonal close-packed structure with the aluminium ions filling two-thirds of the octahedral interstices.
Each Al3+ center is octahedral.
In terms of its crystallography, corundum adopts a trigonal Bravais lattice with a space group of R3c (number 167 in the International Tables).
Aluminium oxide also exists in other metastable phases, including the cubic γ and η phases, the monoclinic θ phase, the hexagonal χ phase, the orthorhombic κ phase and the δ phase that can be tetragonal or orthorhombic.

Each has a unique crystal structure and properties.
Cubic γ-Al2O3 has important technical applications.
The so-called β-Al2O3 proved to be NaAl11O17.

Molten aluminium oxide near the melting temperature is roughly 2/3 tetrahedral (i.e. 2/3 of the Al are surrounded by 4 oxygen neighbors), and 1/3 5-coordinated, with very little (<5%) octahedral Al-O present.
Around 80% of the oxygen atoms are shared among three or more Al-O polyhedra, and the majority of inter-polyhedral connections are corner-sharing, with the remaining 10–20% being edge-sharing.

The breakdown of octahedra upon melting is accompanied by a relatively large volume increase (~33%), the density of the liquid close to its melting point is 2.93 g/cm3.
The structure of molten alumina is temperature dependent and the fraction of 5- and 6-fold aluminium increases during cooling (and supercooling), at the expense of tetrahedral AlO4 units, approaching the local structural arrangements found in amorphous alumina.

PRODUCTION OF ALUMINIUM OXIDE:
Aluminium hydroxide minerals are the main component of bauxite, the principal ore of aluminium.
A mixture of the minerals comprise bauxite ore, including gibbsite (Al(OH)3), boehmite (γ-AlO(OH)), and diaspore (α-AlO(OH)), along with impurities of iron oxides and hydroxides, quartz and clay minerals.[
Bauxites are found in laterites.

Bauxite is typically purified using the Bayer process:
Al2O3 + H2O + NaOH → NaAl(OH)4
Al(OH)3 + NaOH → NaAl(OH)4
Except for SiO2, the other components of bauxite do not dissolve in base.
Upon filtering the basic mixture, Fe2O3 is removed.
When the Bayer liquor is cooled, Al(OH)3 precipitates, leaving the silicates in solution.
NaAl(OH)4 → NaOH + Al(OH)3
The solid Al(OH)3 Gibbsite is then calcined (heated to over 1100 °C) to give aluminium oxide:
2 Al(OH)3 → Al2O3 + 3 H2O

The product aluminium oxide tends to be multi-phase, i.e., consisting of several phases of aluminium oxide rather than solely corundum.
The production process can therefore be optimized to produce a tailored product.
The type of phases present affects, for example, the solubility and pore structure of the aluminium oxide product which, in turn, affects the cost of aluminium production and pollution control.

APPLICATIONS OF ALUMINIUM OXIDE:
Known as alpha alumina in materials science communities or alundum (in fused form) or aloxite in the mining and ceramic communities aluminium oxide finds wide use.
Annual world production of aluminium oxide in 2015 was approximately 115 million tonnes, over 90% of which is used in the manufacture of aluminium metal.
The major uses of speciality aluminium oxides are in refractories, ceramics, polishing and abrasive applications.

Large tonnages of aluminium hydroxide, from which alumina is derived, are used in the manufacture of zeolites, coating titania pigments, and as a fire retardant/smoke suppressant.
Over 90% of the aluminium oxide, normally termed Smelter Grade Alumina (SGA), produced is consumed for the production of aluminium, usually by the Hall–Héroult process.
The remainder, normally called speciality alumina is used in a wide variety of applications which reflect its inertness, temperature resistance and electrical resistance.

Fillers:
Being fairly chemically inert and white, aluminium oxide is a favored filler for plastics.
Aluminium oxide is a common ingredient in sunscreen and is sometimes also present in cosmetics such as blush, lipstick, and nail polish.

Glass:
Many formulations of glass have aluminium oxide as an ingredient.
Aluminosilicate glass is a commonly used type of glass that often contains 5% to 10% alumina.

Catalysis:
Aluminium oxide catalyses a variety of reactions that are useful industrially.
In its largest scale application, aluminium oxide is the catalyst in the Claus process for converting hydrogen sulfide waste gases into elemental sulfur in refineries.
Aluminium oxide is also useful for dehydration of alcohols to alkenes.
Aluminium oxide serves as a catalyst support for many industrial catalysts, such as those used in hydrodesulfurization and some Ziegler–Natta polymerizations.

Gas purification:
Aluminium oxide is widely used to remove water from gas streams.

Abrasive:
Aluminium oxide is used for its hardness and strength.
Its naturally occurring form, corundum, is a 9 on the Mohs scale of mineral hardness (just below diamond).
Aluminium oxide is widely used as an abrasive, including as a much less expensive substitute for industrial diamond. Many types of sandpaper use aluminium oxide crystals.

In addition, its low heat retention and low specific heat make it widely used in grinding operations, particularly cutoff tools.
As the powdery abrasive mineral aloxite, it is a major component, along with silica, of the cue tip "chalk" used in billiards.
Aluminium oxide powder is used in some CD/DVD polishing and scratch-repair kits.
Its polishing qualities are also behind its use in toothpaste.
Aluminium oxide is also used in microdermabrasion, both in the machine process available through dermatologists and estheticians, and as a manual dermal abrasive used according to manufacturer directions.

Paint:
Aluminium oxide flakes are used in paint for reflective decorative effects, such as in the automotive or cosmetic industries.[citation needed]

Composite fiber:
Aluminium oxide has been used in a few experimental and commercial fiber materials for high-performance applications (e.g., Fiber FP, Nextel 610, Nextel 720).
Alumina nanofibers in particular have become a research field of interest.

Armor:
Some body armors utilize alumina ceramic plates, usually in combination with aramid or UHMWPE backing to achieve effectiveness against most rifle threats.
Alumina ceramic armor is readily available to most civilians in jurisdictions where it is legal, but is not considered military grade.
Aluminium oxide is also used to produce bullet-proof alumina glass capable to withstand impact of .50 BMG calibre rounds.

Abrasion protection:
Aluminium oxide can be grown as a coating on aluminium by anodizing or by plasma electrolytic oxidation (see the "Properties" above).
Both the hardness and abrasion-resistant characteristics of the coating originate from the high strength of aluminium oxide, yet the porous coating layer produced with conventional direct current anodizing procedures is within a 60–70 Rockwell hardness C range which is comparable only to hardened carbon steel alloys, but considerably inferior to the hardness of natural and synthetic corundum. Instead, with plasma electrolytic oxidation, the coating is porous only on the surface oxide layer while the lower oxide layers are much more compact than with standard DC anodizing procedures and present a higher crystallinity due to the oxide layers being remelted and densified to obtain α-Al2O3 clusters with much higher coating hardness values circa 2000 Vickers hardness.
Alumina is used to manufacture tiles which are attached inside pulverized fuel lines and flue gas ducting on coal fired power stations to protect high wear areas.
They are not suitable for areas with high impact forces as these tiles are brittle and susceptible to breakage.

Electrical insulation:
Aluminium oxide is an electrical insulator used as a substrate (silicon on sapphire) for integrated circuits but also as a tunnel barrier for the fabrication of superconducting devices such as single-electron transistors and superconducting quantum interference devices (SQUIDs).

For its application as an electrical insulator in integrated circuits, where the conformal growth of a thin film is a prerequisite and the preferred growth mode is atomic layer deposition, Al2O3 films can be prepared by the chemical exchange between trimethylaluminum (Al(CH3)3) and H2O:
2 Al(CH3)3 + 3 H2O → Al2O3 + 6 CH4
H2O in the above reaction can be replaced by ozone (O3) as the active oxidant and the following reaction then takes place:
2 Al(CH3)3 + O3 → Al2O3 + 3 C2H6
The Al2O3 films prepared using O3 show 10–100 times lower leakage current density compared with those prepared by H2O.

Aluminium oxide, being a dielectric with relatively large band gap, is used as an insulating barrier in capacitors.[

Other:
In lighting, translucent aluminium oxide is used in some sodium vapor lamps.
Aluminium oxide is also used in preparation of coating suspensions in compact fluorescent lamps.
In chemistry laboratories, aluminium oxide is a medium for chromatography, available in basic (pH 9.5), acidic (pH 4.5 when in water) and neutral formulations.

Health and medical applications include it as a material in hip replacements and birth control pills.
Aluminium oxide is used as a scintillator and dosimeter for radiation protection and therapy applications for its optically stimulated luminescence properties.

Insulation for high-temperature furnaces is often manufactured from aluminium oxide.
Sometimes the insulation has varying percentages of silica depending on the temperature rating of the material.

The insulation can be made in blanket, board, brick and loose fiber forms for various application requirements.
Small pieces of aluminium oxide are often used as boiling chips in chemistry.
Aluminium oxide is also used to make spark plug insulators.

Using a plasma spray process and mixed with titania, it is coated onto the braking surface of some bicycle rims to provide abrasion and wear resistance.
Most ceramic eyes on fishing rods are circular rings made from aluminium oxide.
In its finest powdered (white) form, called Diamantine, aluminium oxide is used as a superior polishing abrasive in watchmaking and clockmaking.

Aluminium oxide is also used in the coating of stanchions in the motorcross and mountainbike industry.
This coating is combined with molybdenumdisulfate to provide long term lubrication of the surface.


QUESTIONS AND ANSWERS ABOUT ALUMINIUM OXIDE:
What is aluminium oxide used for?
Aluminium oxide is a very good ceramic oxide which has many important applications in the manufacture of adsorbents and catalysts.
Aluminium oxide is also used in the aerospace industry and in the production of many commercially important chemicals.

How can aluminium oxide be produced?
Aluminium oxide can be obtained from the calcination of Gibbsite, which is denoted by the chemical formula Al(OH)3.
The chemical equation for this reaction is given by:
2Al(OH)3 → 3H2O + Al2O3

Is aluminium(III) oxide acidic or basic?
Aluminium(III) oxide is an amphoteric metal oxide, i.e. this compound exhibits both acidic and basic qualities.
The nature of the other reactant in the chemical reaction decides the acidic or basic nature of Al2O3

What liquids react aluminium?
Aluminium reacts with dilute hydrochloric acid to form aluminium chloride and hydrogen gas. Chlorine and liquid bromine react with aluminium at room temperature.

Why can’t aluminium react with water?
Aluminium metal rapidly develops a thin layer of aluminium oxide of a few millimetres that prevents the metal from reacting with water.
When this layer is corroded a reaction develops, releasing highly flammable hydrogen gas.


SAFETY INFORMATION ABOUT ALUMINIUM OXIDE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.


SYNONYMS OF ALUMINUM OXIDE :
MeSH Entry Terms:
Alumina
Alumina Ceramic
Aluminum Oxide
Aluminum Oxide (Al130O40)
Aluminum Oxide (Al2O)
Aluminum Oxide (AlO2)
Bauxite
Ceramic, Alumina
Corundum
Oxide, Aluminum
Sapphire
Depositor-Supplied Synonyms:
ALUMINUM OXIDE
Aluminium oxide
1344-28-1
Aluminum lake
dialuminum;oxygen(2-)
BETA-ALUMINIUM OXIDE
GAMMA-ALUMINIUM OXIDE
LMI26O6933
12522-88-2
12737-16-5
Fasertonerde
Abramant
Abramax
Abrarex
Abrasit
Aloxite
Alundum
Compalox
Conopal
Faserton
Lucalox
Martoxin
Poraminar
Almite
delta alumina
Diadur
Saffie
Dural
Dispal alumina
Theta alumina
Alumina Ceramic
Eta-alumina
Aluminum oxide, mesoporous
Aluminum trioxide
Catapal S
Jubenon R
Microgrit WCA
Neobead C
Dispal M
Hypalox II
Ketjen B
Alumite (oxide)
Cab-O-grip
Fiber FP
Ludox CL
Aluminite 37
Dialuminum trioxide
Alon C
Aluminum sesquioxide
Catapal SB alumina
Alundum 600
Dotment 324
Dotment 358
GK (Oxide)
Alcoa F 1
Exolon XW 60
A 1 (Sorbent)
PS 1 (Alumina)
Activated aluminum oxide
F 360 (Alumina)
G 0 (Oxide)
G 2 (Oxide)
Brockmann, aluminum oxide
Q-Loid A 30
Aluminum oxide (Brockmann)
KHP 2
RC 172DBM
Aluminum oxide (fibrous forms)
CCRIS 6605
HSDB 506
LA 6
Aluminum oxide [NF]
Aluminum oxide (brockmann) (form)
Aluminum oxide (ignited)
EINECS 215-691-6
KA 101
A1-1401 P(MS)
aluminiumoxid
alpha alumina
gamma alumina
UNII-LMI26O6933
A1-0109 P
A1-3916 P
A1-3970 P
AI3-02904
Double-pass AAO Template 2.5 cm(D: 100nm,hole depth: 60 mum)
Activated alumina
Aluminum oxide G
A1-3438 T 1/8''
EINECS 254-434-2
Nano Aluminum Oxide
Aluminum oxide gamma
Aluminum oxide, AR
A1-0104 T 3/16''
A1-1404 T 3/16''
A1-3945 E 1/16''
A1-3980 T 5/32''
A1-4028 T 3/16''
A1-4126 E 1/16''
Alumina Nanoparticles
Iron Oxide Dispersion
Aluminum (II) oxide
Nano Alumina Dispersion
ALUMINA [HPUS]
ALUMINA [INCI]
Alumina Slurry Polishing
Aluminum Oxide Nanowires
Aluminium oxide nanowires
Alumina Sputtering Target
Aluminum Oxide Dispersion
Aluminium Oxide Dispersion
Aluminium Oxide Nanopowder
EC 215-691-6
Alumina (Alpha) Nanopowder
Alumina (Gamma) Nanopowder
ALUMINUM OXIDE [II]
ALUMINUM OXIDE [MI]
ALUMINUM OXIDE [HSDB]
gamma-Alumina oxide Nanopowder
alpha- Alumina oxide Nanopowder
ALUMINIUM OXIDE [MART.]
DTXSID1052791
ALUMINIUM OXIDE [WHO-DD]
Aluminium Oxide Sputtering Target
Aluminum oxide, SP,99.999%
Aluminum Oxide Nanoparticle Disperson
AKOS030228258
DB11342
Aluminum Oxide Nanoparticles / Nanopowder
Aluminum Oxide Nanopowder / Nanoparticles
Large aperture AAO template 180-250nm
Large aperture AAO template 250-300nm
Large aperture AAO template 300-350nm
V type AAO Template(hole depth:260 nm)
Aluminum Oxide Nanoparticles, Silane Coated
V type AAO Template(hole depth :500 nm)
V type AAO Template(pore diameter: 450 nm)
Alumina Al2O3 Powder / Aluminum Oxide Powder
ALUMINUM OXIDE, ANHYDROUS [EP IMPURITY]
Double-pass AAO Template 1.2 cm(HD:400nm)
V type AAO Template(pore diameter: 90-40 nm)
Zinc Magnesium (Zn-Mg) Alloy Sputtering Targets
Double-pass AAO Template(HD:20-40nm D:1.2cm)
Double-pass AAO Template(HD:20-40nm D:2.5cm)
Double-pass AAO Template(HD:60-80nm D:1.2cm)
Double-pass AAO Template(HD:60-80nm D:2.5cm)
Q177342
Single-pass AAO Template(HD: 200nm,Size:2x2cm)
Single-pass AAO Template(HD: 300nm,Size:2x2cm)
Single-pass AAO Template(HD: 400nm,Size:2x2cm)
Single-pass AAO Template(HD: 500nm,Size:2x2cm)
Single-pass AAO Template(HD: 600nm,Size:2x2cm)
Single-pass AAO Template(HD: 700nm,Size:2x2cm)
Aluminum oxide, 99.99% metals basis, 56mum, powder
Single-pass AAO Template(Thickness:5mum, HD:300nm)
Single-pass AAO Template(thickness: 1mum,HD:5-10 nm)
Single-pass AAO Template(thickness: 50nm,HD:5-10 nm)
Single-pass AAO Template(Thickness:60mum, HD:300nm)
Single-pass AAO Template(thickness: 300nm, HD:40-50 nm)
Single-pass AAO Template(thickness: 300nm, HD:60-80 nm)
Single-pass AAO Template(thickness: 300nm,HD:20-30 nm)
Single-pass AAO Template(thickness: 5mum, HD: 60-80 nm)
Single-pass AAO Template(Thickness: 5mum,HD:20-30 nm)
Single-pass AAO Template(Thickness: 60mum, HD:20-30 nm)
Single-pass AAO Template(Thickness:300nm, HD:80-100nm)
Aluminum oxide, activated, neutral, Brockmann I 58 A pore size
Single-pass AAO Template Thickness 5mum(D: 50nm, Square 2cm)
Single-pass AAO Template(thickness: 60mum, HD: 60-80 nm)
Al2O3 Alumina Spherical Powder / Aluminum Oxide Spherical Powder
Double-pass AAO Template 1.2 cm(D: 100nm,hole depth: 50 mum)
Double-pass AAO Template 1.2 cm(D: 200nm,hole depth: 50 mum)
Double-pass AAO Template 1.2 cm(D: 300nm,hole depth: 50 mum)
Double-pass AAO Template 1.2 cm(D: 50nm,hole depth: 50 mum)
Double-pass AAO Template 2.5 cm(D: 200nm,hole depth: 60 mum)
Double-pass AAO Template 2.5 cm(D: 300nm,hole depth: 60 mum)
Double-pass AAO Template 2.5 cm(D: 400nm,hole depth: 60 mum)
Double-pass AAO Template 2.5 cm(D: 50nm,hole depth: 60 mum)
Single-pass AAO Template Thickness 50mum(D: 100nm, Square 2cm)
Single-pass AAO Template Thickness 50mum(D: 200nm, Square 2cm)
Single-pass AAO Template Thickness 50mum(D: 400nm, Square 2cm)
Single-pass AAO Template Thickness 50mum(D: 50nm, Square 2cm)
Single-pass AAO Template Thickness 5mum(D: 100nm, Square 2cm)
Single-pass AAO Template Thickness 5mum(D: 200nm, Square 2cm)
Single-pass AAO Template Thickness 5mum(D: 400nm, Square 2cm)
Transferable AAO ultrathin films 60-70 nm(HD: 30nm, S:>/=1cm2)
Transferable AAO ultrathin films 60-70 nm(HD: 40nm, S:>/=1cm2)
Transferable AAO ultrathin films 60-70 nm(HD: 50nm, S:>/=1cm2)
AAO double-pass filter membrane 200 nm(D: 25 mm, Hole depth: 200 nm)
AAO double-pass filter membrane 200 nm(D: 47 mm, Hole depth: 200 nm)
AAO double-pass filter membrane 300 nm(D: 25 mm, Hole depth: 300 nm)
AAO double-pass filter membrane 300 nm(D: 47 mm, Hole depth: 300 nm)
AAO double-pass filter membrane 400 nm(D: 25 mm, Hole depth: 400 nm)
AAO double-pass filter membrane 400 nm(D: 47 mm, Hole depth: 400 nm)
Double-pass AAO Template 1.2 cm(D:40-60nm,hole depth: 40-70 mum)
Transferable AAO ultrathin films 100-110 nm(HD: 60nm, S:>/=1cm2)
Transferable AAO ultrathin films 100-110 nm(HD: 70nm, S:>/=1cm2)
Transferable AAO ultrathin films 100-110 nm(HD: 80nm, S:>/=1cm2)
Transferable AAO ultrathin films 100-110 nm(HD: 90nm, S:>/=1cm2)

ALUMINIUM SILICATE
ALUMINIUM SILICATE


CAS Number: 12141-46-7
EC Number: 215-113-2
MDL number: MFCD00058866
Molecular Formula: 3Al2O3 · 2SiO2


Aluminium Silicate is a naturally-occurring rock or soil constituent characterized by particles with a diameter of less than 0.005 mm.
Aluminium Silicate is composed primarily of hydrous aluminum silicates, trace amounts of metal OXIDES, and organic matter.
Aluminium silicate (or aluminum silicate) is a name commonly applied to chemical compounds which are derived from aluminium oxide, Al2O3 and silicon dioxide, SiO2 which may be anhydrous or hydrated, naturally occurring as minerals or synthetic.
Their chemical formulae are often expressed as xAl2O3·ySiO2·zH2O.


Aluminium Silicate is known as E number E559.
Aluminium Silicate, also known as aluminium silicate, is a mixture of aluminum, silica, and oxygen that can be either a mineral, or combined with water to form a clay.
Aluminium Silicate can also combine with other elements to form various other minerals or clays.


Aluminium Silicate retains its strength at high temperatures — a property known as being refractory.
Mineral Aluminium Silicate comes in three different forms — kyanite, andalusite, or sillimanite.
They all have the chemical formula Al2SiO5, but they have different crystal structures.
All three forms are rarely found in the same rock, because each occurs under different conditions of pressure and temperature.


Only kyanite and sillimanite are used industrially.
Kyanite is unusual in that its hardness varies, depending on the direction of the crystals.
Some of the crystals are similar to blue sapphires and are used as gemstones.
Kyanite is also used in the making of the frequently used industrial compound mullite.


This compound has the chemical formula 3Al2O3.2SiO2.
Sillimanite can also be used as a refractory.
It is used in a variety of industries.
These include glass-making, ceramics, cement, iron foundries, and metal smelting.


Examples of Aluminium Silicate:
Al2SiO5, (Al2O3·SiO2), which occurs naturally as the minerals andalusite, kyanite and sillimanite which have different crystal structures.
Al2Si2O5(OH)4, (Al2O3·2SiO2·2H2O), which occurs naturally as the mineral kaolinite and is also called aluminium silicate dihydrate.
It is a fine white powder and is used as a filler in paper and rubber and also used in paints.
Al2Si2O7, (Al2O3·2SiO2), called metakaolinite, formed from kaolin by heating at 450 °C (842 °F).


Al6Si2O13, (3Al2O3·2SiO2), the mineral mullite, the only thermodynamically stable intermediate phase in the Al2O3-SiO2 system at atmospheric pressure.
This also called '3:2 mullite' to distinguish it from 2Al2O3·SiO2, Al4SiO8 '2:1 mullite'.
2Al2O3·SiO2, Al4SiO8 '2:1 mullite'.


Bentonite is an aluminum silicate-based material, which is an aggregate of lamellar platelets packed together.
Aluminium Silicate material (known as M120F) is a composite of around half alumina and half silicon oxide which features good thermal shock resistance and easily replaces carbon fixtures in many applications.
By changing process conditions, this highly versatile material can be tailored to provide a range of hardness values to suit customer requirements, whilst maintaining its thermal and electrical properties.
Aluminium Silicate is excellent for the manufacture of fixtures, firing and dicing plates, and is flexible enough to be manufactured into intricate designs specified by our customers.


Aluminum silicate can be hydrated, or have water molecules associated with it.
In this case, Aluminium Silicate forms a clay.
Kaolin is the term for a group of clay minerals with the chemical formula of Al2O3.2SiO2.2H20.
It forms a layer of two alternating crystals — one of silicon-oxygen and one of alumina.
Kaolinite is the main constituent of kaolin.


Kaolin has been used for many years to control diarrhea and to dry poison ivy and poison oak rashes.
It has also been used to treat diaper rash.
Commercially, it has been important in the ceramics industry, particularly for the production of fine porcelain.
It is also used to manufacture cement, bricks, and insulators, among other things.


Another aluminum silicate compound found as a mineral and as a clay is magnesium aluminum silicate, which is composed of magnesium, aluminum, silica, and oxygen.
In its mineral form, it is a type of garnet called pyrope.
It is often used as a gemstone, and is the only garnet to always be red in color.
Its chemical formula is Mg3Al2(SiO4)3, although there are frequently trace amounts of other elements present.


Sodium aluminum silicate is also referred to as sodium aluminosilicate and is composed of sodium, aluminum, silica, and oxygen.
Two minerals of this type are albite and jadeite.
Albite has the chemical formula of NaAlSi3O8, while that of jadeite is NaAlSi2O6.
Albite is common in Earth’s crust, and breaks down under pressure to form jadeite and quartz.
Jadeite is one of the types of minerals that make up the gemstone jade.


There is an industrial form of sodium aluminosilicate, known as synthetic amorphous sodium aluminosilicate, that contains water.
This is a series of compounds and does not have a fixed chemical composition.
It is used as an additive in powdered foods to keep lumps from forming.
Synthetic zeolites are prepared from sodium aluminosilicate.


These are minerals that are very porous, and are used commercially as adsorbents.
They are used primarily as laundry detergents, although they have a variety of other industrial uses.
Aluminium Silicate refers to compounds gotten from both aluminum oxide and silicon dioxide.
Aluminium Silicate generally has a molecular weight of 162 g/mol.
There are various types of Aluminium Silicate, and these compounds could come in a natural or synthetic form.


When Aluminium Silicate has no water added to it, it can be found in the form of minerals such as sillimanite, kyanite, and andalusite.
These minerals have a common chemical formula (Al2SiO5) but can be differentiated by their crystal structure.
When Aluminium Silicate is hydrated, it gives rise to Kaolin.
Kaolin is a clay mineral.
Its chemical formula is Al2O3.2SiO2.2H2O.
The various forms of aluminum silicate have their unique properties and application.


Calcined kaolin is an anhydrous aluminium silicate produced by heating natural china clay to high temperatures in a kiln.
This calcination process gives an increase in hardness and alters the particle shape of the kaolin.
When calcination occurs at around 700°C, the dehydroxylation of the kaolin is complete, forming a partially crystalline metakaolin.
Fully calcined products with an amorphous defect spinel structure are formed above 980°C.
Fully calcined kaolin can be treated with silane to give a particle surface capable of chemically coupling with the polymer.


The heat treatment process makes calcined kaolins X-ray amorphous, but they substantially retain their kaolin shape and are used extensively in the pharmaceutical, power cable insulation, extruded profile and film industries.
Interfacial fusion during calcination decreases the aspect ratio and gives them an inert surface.
They also give excellent electrical insulation performance and low dielectric loss due to the lack of crystallinity .
Calcine Kaolin is used pharmaceutical rubber, profile extrusion, thermoplastic vulcanisates (TPV's), rubber cable, high quality rubber flooring, hose, polyurethane sealants, thermal barrier film, antiblock film, seals & gaskets, plasticised PVC cable.



USES and APPLICATIONS of ALUMINIUM SILICATE:
Some of these forms of Aluminium Silicate are used medicinally and industrially.
Some Aluminium Silicate is used as gemstones.
The hydrated form of magnesium aluminum silicate is a mixture of clays.
This purified mixture, Aluminium Silicate is commonly used as an antacid.
Aluminium Silicate is also used as a thickener in beauty products and cosmetics, and as an inactive ingredient in deodorants.


Aluminium Silicate is used as a refractory in the ceramics industry and in the manufacture of many things, including high voltage electrical insulations, glass, and heating elements.
Aluminium Silicate is used same as for clay i.e. ceramic products, refractories, colloidal suspensions, oil-well drilling fluids, filler for rubber and plastic products, films, paper coating, decolorizing oils, temporary molds, filtration, carrier in insecticidal sprays, catalyst support.
Aluminium Silicate compound in its various forms is used in different industries.
This makes Aluminium Silicate one of the most highly sought-after compounds.


-Refractory Bricks:
Aluminum silicate polymorphs are used to produce refractory products.
These bricks are made to withstand high temperatures without any damage.
These bricks are usually used in furnaces and ovens.


-Porcelain Fixtures:
Aluminum silicate is used as a raw material in making porcelain fixtures.
Kaolin is subjected to a high temperature to produce porcelain.


-Jewelry:
Andalusite, sillimanite, and kyanite are commonly used in making jewelry.
This use can be attributed to their characteristic luster.
Kyanite is especially appreciated for its blue color.


-Cosmetics:
In the cosmetic industry, aluminum silicate is used to make a wide range of products.
It is used in the manufacture of face masks, face powders, and lotions.
This is because aluminum silicate has a high absorbance for oil.


-Medicine:
Kaolin has a lot of important uses in medicine.
It is used to promote blood clotting.
In addition, it is used to treat diarrhea.


-Filler:
Aluminum silicate is used as a filler to add bulk to products in various industries.
It is used as a filler in rubber, paper, ceramic, and drug manufacturing.


-Pregnancy:
In some parts of Africa such as Nigeria, Gabon, and Cameroun, pregnant women eat Kaolin for pleasure.
It is a popular craving among pregnant women.


-Aluminium silicate applications:
*Boats
*Fixtures
*Nozzles
*Furnace tooling
*Slicing tooling
*Insulators
*Glass sealing
*Brazing
*Alloying
*Soldering
*Welding



ANDALUSITE:
Andalusite is one of the naturally occurring forms of aluminum silicate.
This form of aluminum silicate is usually found in metamorphic rocks.
It is named after a community in Spain known as Andalusia.
However, studies have shown that this mineral was originally found in, Guadalajara, a province in Spain.

In recent times, commercial quantities of Andalusite have been found in Brazil, the United States of America, Russia, South Africa, Zimbabwe, and Sri Lanka.
Andalusite can be found in a wide range of colors.
It could be gray, green, white, pink, yellow, or even violet.
Like other aluminum silicate minerals, its chemical formula is Al2SiO5.
However, it has an orthorhombic crystal lattice.



KYANITE:
Kyanite is another form of aluminum silicate.
This form of aluminum silicate is often found in metamorphic and sedimentary rocks.
It is also referred to as disthene or cyanite.
Also, kyanite is more stable at high pressure than the other aluminum silicate minerals.
As opposed to the other aluminum silicate compounds with its chemical formula, kyanite has a triclinic crystal system.

The strength of kyanite is highly dependent on its direction.
For instance, it shows more strength perpendicular to an axis and shows less strength parallel to the same axis.
For this reason, it is described as anisotropic.
This mineral compound usually appears blue.
However, it can also appear green, white, or gray.
Nepal, Tibet, Brazil, Kenya, the United States of America, and Russia are some places where Kyanites can be found.



SILLIMANITE:
This tough aluminum silicate compound derived its name from an American chemist called Benjamin Silliman.
It is usually stable under high temperatures.
Sillimanite is usually gotten from sedimentary rocks.
It has the same chemical formula as the other aluminum silicate minerals.
Sillimanite has an orthorhombic crystal system.

This mineral can occur in a wide range of colors.
It can be colorless, green, yellow, brown, blue, or grey.
Sillimanite occurs in a form known as fibrolite.
This form of sillimanite is so named because it exists like bundles of twisted fibers.
It can be found in Brazil, Sri Lanka, Germany, Italy, and India.



KAOLIN:
This aluminum silicate is also called china clay.
It is formed when aluminum silicate is hydrated.
It commonly exists as a cream-colored claylike mass.
Kaolin is flexible but it is not elastic.
It usually has a dull appearance, unlike sillimanite, kyanite, and andalusite.

It derives its name from a Chinese village called Gaoling.
Kaolin is usually derived from soils formed from weathered rocks in humid places like tropical rainforests.
It is usually found in countries such as South Africa, China, Malaysia, France, Pakistan, Tanzania, Brazil, Iran, and the United States of America.
Kaolin has a wide range of uses in various parts of the world.



ALUMINIUM SILICATE COMPOSITE MATERIALS, FIBERS:
Aluminium silicate is a type of fibrous material made of aluminium oxide and silicon dioxide, (such materials are also called aluminosilicate fibres).
These are glassy solid solutions rather than chemical compounds.
The compositions are often described in terms of % weight of alumina, Al2O3 and silica, SiO2.
Temperature resistance increases as the % alumina increases.
These fibrous materials can be encountered as loose wool, blanket, felt, paper or boards.



PHYSICAL and CHEMICAL PROPERTIES of ALUMINIUM SILICATE:
Molecular Weight: 162.05
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 0
Exact Mass: 161.914576
Monoisotopic Mass: 161.914576
Topological Polar Surface Area: 5 Ų
Heavy Atom Count: 8
Formal Charge: 0
Complexity: 0
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 8
Compound Is Canonicalized: Yes
Physical state: fibers
Color: No data available
Odor: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flammability (solid, gas): The product is not flammable.
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: No data available

pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: < 0,07 g/l at 20 °C - insoluble
Partition coefficient:
n-octanol/water: Not applicable for inorganic substances
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available



FIRST AID MEASURES of ALUMINIUM SILICATE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ALUMINIUM SILICATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of ALUMINIUM SILICATE:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ALUMINIUM SILICATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Use safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ALUMINIUM SILICATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
*Storage class:
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of ALUMINIUM SILICATE:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available
-Incompatible materials:
No data available



SYNONYMS:
Aluminosilicate, Mullite
Clay
UNII-T1FAD4SS2M
Aluminum silicate, natural
Aluminum silicate, synthetic
EINECS 235-253-8

ALUMINIUM SILICATE
Aluminum silicate (or aluminium silicate) is a name commonly applied to chemical compounds which are derived from aluminium oxide, Al2O3 and silicon dioxide, SiO2 which may be anhydrous or hydrated, naturally occurring as minerals or synthetic.
Their chemical formulae are often expressed as xAl2O3·ySiO2·zH2O.
Aluminum silicate is known as E number E559.

CAS: 12141-46-7
MF: Al2O5Si
MW: 162.05
EINECS: 235-253-8

Synonyms
Alumina Silicate;dialuminum,oxygen(2-),silicon(4+);Aluminum silicate felt;Aluminum silicate fibre tube;Aluminum silicate fiberboard;ALUMINIUL SILICATE;Aluminumoxidesilicate;aluminumoxidesilicate(al2o(sio4));Clay;UNII-T1FAD4SS2M;Aluminum silicate, natural;T1FAD4SS2M;Aluminum silicate, synthetic;ALUMINUM OXIDE SILICATE;Aluminum silicate, natural [JAN];Aluminum silicate, synthetic [JAN];EINECS 235-253-8;XLIDPNGFCHXNGX-UHFFFAOYSA-N

Aluminum silicate is a synthetic mineral produced from coal fired power stations as a slag and then cooled immediately in water to form a glass type substance.
Aluminum silicate is a general purpose abrasive to be used in blast pots with an open nozzle and not in a blasting cabinet.
Aluminum silicate can be used on a variety of materials including, steel, wood, and brick.
Aluminum silicate is softer then iron silicate and lighter in colour hence preferred for brick, stone and wood work, including oak beams, as it leaves less of a dark residue when blasting.

Aluminum silicate is an amorphous ultra-fine white loose powder.
Has excellent suspension and pure white appearance.
The pH value of water immersion was 9. 70-10. 80.
The apparent density was 0.22-0. 28kg/L.
Aluminum silicate is a kind of functional silicate which can improve the color strength and hiding performance of pigment.
The ratio of alumina to silica is not constant.
Insoluble in water and acid.
Existed in the dirt.
These two oxides can be obtained by mixing them in proportion and sintering them.

Aluminum silicate is an aluminosilicate, commonly known as "kyanite", "red silica" and "sillimanite".
Chemical formula Al2O3 SiO2.
Molecular weight 162.04.
White orthogonal crystal.
Aluminum silicate has glass luster and transparent body.
The melting point is 1545 ℃ (converted into Al2O3 · 2 SiO2), the boiling point is higher than 1545 ℃, the relative density is 3.247, and the refractive index is 1.66.
Soluble in molten alkali, insoluble in water, hydrochloric acid, sulfuric acid.
Decompose in case of hydrogen fluoride.
Aluminum silicate exists in nature in mineral form.

Natural mineral is also called "mullite", chemical formula 3 Al2O3 2 SiO2, colorless orthogonal crystal, melting point 1920 ℃, relative density 3.156, refractive index 1.638(1.642, 1.653), insoluble in acid and water.
Uses: Used to make glass, pottery, refractory materials, gems, technical ceramics, pigments and fillers in paints.
Aluminum silicate's natural minerals are used to make clay bricks, high alumina bricks and porcelain.
Aluminum silicate is mainly used to make high temperature resistant fireproof sound insulation cotton, plates, pipes, seam felt, fireproof insulation cloth, high temperature resistant paper, fire-resistant insulation rope, belt, fireproof insulation needle punching blanket (with silk throwing and blowing) and brick.
Inorganic fireproof decorative panel.
Inorganic fire shutter, etc.

Main representatives
Andalusite, kyanite, and sillimanite are the principal aluminium silicate minerals.
The triple point of the three polymorphs is located at a temperature of 500 °C (932 °F) and a pressure of 0.4 GPa (58,000 psi).
These three minerals are commonly used as index minerals in metamorphic rocks.

Physical and Chemical Properties
Amorphous ultra-fine white loose powder.
Has excellent suspension and pure white appearance.
The pH value of water immersion is 9.70~10.80.
The apparent density was 0.22-0.28/L.
Aluminum silicate is a kind of functional silicate which can improve the color strength and hiding performance of pigment.

Al2SiO5, (Al2O3·SiO2), which occurs naturally as the minerals andalusite, kyanite and sillimanite which have distinct crystal structures.
Al2Si2O7, (Al2O3·2SiO2), called metakaolinite, formed from kaolin by heating at 450 °C (842 °F).
Al6Si2O13, (3Al2O3·2SiO2), the mineral mullite, the only thermodynamically stable intermediate phase in the Al2O3-SiO2 system at atmospheric pressure.
This also called '3:2 mullite' to distinguish it from 2Al2O3·SiO2, Al4SiO8 '2:1 mullite'.
2Al2O3·SiO2, Al4SiO8 '2:1 mullite.
The above list mentions ternary materials (Si-Al-O).
Kaolinite is a quaternary material (Si-Al-O-H).
Also called Aluminum silicate dihydrate, kaolinite occurs naturally as a mineral.
Aluminum silicate's formula is Al2Si2O5(OH)4, (Al2O3·2SiO2·2H2O).

Aluminium silicate composite materials, fibres
Aluminium silicate is a type of fibrous material made of aluminium oxide and silicon dioxide, (such materials are also called aluminosilicate fibres).
These are glassy solid solutions rather than chemical compounds.
The compositions are often described in terms of % weight of alumina, Al2O3 and silica, SiO2.
Temperature resistance increases as the % alumina increases.
These fibrous materials can be encountered as loose wool, blanket, felt, paper or boards.

Uses
In dental cements, glass industry; manufacture of semiprecious stones, enamels, ceramics, and colored lakes; paint filler; in washing compounds.
ALUMINIUM SILICATE
Aluminium Silicate is a synthetic mineral produced from coal fired power stations as a slag and then cooled immediately in water to form a glass type substance.
Aluminium silicate minerals consist of varying proportions of aluminum (Al), silicon (Si), and oxygen (O), often combined with other elements.
Aluminum silicate (or aluminium silicate) is a name commonly applied to chemical compounds which are derived from aluminium oxide, Al2O3 and silicon dioxide, SiO2 which may be anhydrous or hydrated, naturally occurring as minerals or synthetic.

CAS Number: 139264-88-3
Molecular Formula: Al2O5Si
Molecular Weight: 162.05
EINECS Number: 629-654-0

Silicic acid, aluminum salt, 14504-95-1, dialuminum;dioxido(oxo)silane, ALUMINATESILICATE, Silicic acid (H2SiO3), aluminum salt (3:2), 1335-30-4, Dialuminum silicate, 1327-36-2, 139264-88-3, Oxo-bis[(2-oxo-1,3,2,4-dioxasilalumetan-4-yl)oxy]silane, Aluminium silicate(3:2), Aluminum oxide (Al2O3), compd. with montmorillonite ((Al1.33-1.67Mg0.33-0.67)(Ca0-1Na0-1)0.33Si4(OH)2O10.xH2O) (9CI), EINECS 238-509-7, Aluminumsilicate(Al2SiO5), Aluminum silicate (Al2SiO5), Aluminum silicate (Al2(SiO3)3), DTXSID701014506

Aluminium silicate refers to a group of minerals composed primarily of aluminum, silicon, and oxygen.
These minerals belong to the larger class of silicate minerals, which are characterized by the presence of silica tetrahedra (SiO₄) as their fundamental building blocks.
Aluminium silicate minerals are abundant in the Earth's crust and have various industrial applications.

Aluminium silicate, kyanite, and sillimanite are three polymorphs minerals that belong to the nesosilicate minerals.
Hence they have the same chemical formula [Al2SiO5 = Al2O3·SiO2] and all contain theoretically 62.92 wt.% Al2O3 and 37.08 wt.% SiO2.
Andalusite decomposes gradually from 1380 to1400°C with a low volume increase of 5 to 6 vol.%.

Aluminum Silicate is a complex inorganic salt that has a composition consisting generally of 1mole of alumina and 1 to 3 moles of silica.
Andalusite, kyanite, and sillimanite are the principal aluminium silicate minerals.

The triple point of the three polymorphs is located at a temperature of 500 °C (932 °F) and a pressure of 0.4 GPa (58,000 psi).
These three minerals are commonly used as index minerals in metamorphic rocks.
Aluminium silicate is a type of fibrous material made of aluminium oxide and silicon dioxide, (such materials are also called aluminosilicate fibres).

These are glassy solid solutions rather than chemical compounds.
The compositions are often described in terms of % weight of alumina, Al2O3 and silica, SiO2.
Temperature resistance increases as the % alumina increases.

These fibrous materials can be encountered as loose wool, blanket, felt, paper or boards.
Aluminium Silicate is a general purpose abrasive to be used in blast pots with an open nozzle and not in a blasting cabinet.

Aluminium silicate can be used on a variety of materials including, steel, wood, and brick.
Aluminium silicate is softer then iron silicate and lighter in colour hence preferred for brick, stone and wood work, including oak beams, as it leaves less of a dark residue when blasting.
Aluminium silicate is used as a white pigment in paints, printing inks and paper, where it acts as a partial substitute for titanium dioxide (extender) at the same time as it increases the covering power and brightness both of the paint and of the paper.

aluminium silicate is the amorphous sodium and aluminium silicate manufactured by IQESIL and which is used as a white filler in rubber, with a moderate reinforcing nature.
Aluminium silicate is application is especially indicated in the preparation of technical rubber pieces via an extrusion or injection moulding process.
Both the natural and synthetic rubber blends, which contain aluminium silicate present good processability, even with higher filler levels than the reinforcing silica, as well as good vulcanisation properties.

Their slightly alkaline nature permits their use in basic blends.
Aluminium silicate is approved for use in the EU as an insecticide and insect repellent.
Aluminium silicate has low mammalian toxicity.

Aluminium silicate is virtually insoluble in water and in many organic solvents.
Little data has been published regarding its environmental fate.
Aluminum Silicate is clay-like ingredients that are based on silicates.

In cosmetics and personal care products, these ingredients are used in a wide variety of product types, including bath products, makeup and skincare products.
Aluminum Silicate, Calcium Silicate, Magnesium Aluminum Silicate, Magnesium Silicate, Magnesium Trisilicate, Sodium Magnesium Silicate, Zirconium Silicate, Attapulgite, Bentonite, Fuller's Earth, Hectorite, Kaolin, Lithium Magnesium Silicate, Lithium Magnesium Sodium Silicate, Montmorillonite, Pyrophyllite and Zeolite are all clay-like ingredients that are based on silicates.

In cosmetics and personal care products, these seventeen ingredients are used in a wide variety of product types, including bath products, makeup and skincare products.
The general chemical formula for these minerals is Al₂SiO₅.
Aluminium silicate a common clay mineral with the chemical formula Al₂Si₂O₅(OH)₄.

Aluminium silicate is widely used in the ceramics industry and as a component in some medicinal and cosmetic products.
These minerals are polymorphs, meaning they have the same chemical composition but different crystal structures.
They are used in refractory materials and ceramics.

Aluminium silicate a group of minerals that includes aluminum, silicon, and oxygen, often combined with other elements such as potassium, sodium, calcium, or barium.
Feldspar is a major component of many igneous rocks and is used in the glass and ceramics industries.
Aluminium silicate minerals are commonly used in the production of ceramics and pottery due to their heat resistance and ability to form a glassy phase during firing.

Certain aluminium silicate minerals, like andalusite, kyanite, and sillimanite, are used in the production of refractory materials that can withstand high temperatures, making them suitable for applications in furnaces and kilns.
Fillers: Kaolinite, in particular, is used as a filler in the production of paper, rubber, and plastics to improve their physical properties.
Construction Materials: Aluminium silicate minerals can be used in the production of certain construction materials, including bricks and tiles.

Aluminium silicate minerals exhibit a wide range of physical properties depending on their specific composition and crystal structure.
They may have various colors, including white, gray, brown, or green.
The hardness, density, and other physical characteristics vary among different aluminium silicate minerals.

While the minerals themselves are generally considered safe, Aluminium silicate's important to note that certain forms of aluminium silicate, such as respirable crystalline silica dust produced during mining or processing, can pose health risks if inhaled. Occupational safety measures should be followed to prevent exposure.
Aluminum silicate, also known as aluminium silicate, is a mixture of aluminum, silica, and oxygen that can be either a mineral, or combined with water to form a clay.
Aluminium silicate can also combine with other elements to form various other minerals or clays. Some of these forms are used medicinally and industrially.

They retain their strength at high temperatures — a property known as being refractory. Some of the minerals are used as gemstones.
Mineral aluminum silicate comes in three different forms — kyanite, andalusite, or sillimanite.
They all have the chemical formula Al2SiO5, but they have different crystal structures.

All three forms are rarely found in the same rock, because each occurs under different conditions of pressure and temperature.
Only kyanite and sillimanite are used industrially.
Aluminium silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group 1.

Aluminium silicate is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking agent, opacifying agent, viscosity-increasing agent, suspending agent, tablet and capsule disintegrant, and tablet binder.
Aluminium silicate also has antacid properties and is used as a component of some over the counter antacid medications.
Aluminium silicate refers to materials containing anionic Si-O-Al linkages.

Commonly, the associate cations are sodium (Na+), potassium (K+) and protons (H+). Such materials occur as minerals and as synthetic materials, often in the form of zeolites.
Both synthetic and natural aluminosilicates are of technical significance as structural materials, catalysts, and reagents.
Aluminum silicate refers to compounds gotten from both aluminum oxide and silicon dioxide.

Aluminum silicate generally has a molecular weight of 162 g/mol.
There are various types of aluminum silicate, and these compounds could come in a natural or synthetic form.
When aluminum silicate has no water added to it, it can be found in the form of minerals such as sillimanite, kyanite, and andalusite.

These minerals have a common chemical formula (Al2SiO5) but can be differentiated by their crystal structure.
When aluminum silicate is hydrated, it gives rise to Kaolin. Kaolin is a clay mineral.
Aluminium silicate is chemical formula is Al2O3.2SiO2.2H2O.

The various forms of Aluminium silicate have their unique properties and application.
Aluminium silicate is also known as kaolin, or hydrated aluminum silicate when in powder form.
Aluminum silicate is a mixture of alumina, silica, and oxygen.

Aluminium silicate is often used as a demulcent and adsorbent in pharmaceutical industry.
Aluminium silicate is used in color lakes (insoluble dyes).
As a raw material, it is commonly found in paper, plastics, cosmetics, and pharmaceuticals, and it is also used in pharmaceutical preparations as a filtering agent to clarify liquids.

As a medicinal agent, kaolin, is used to treat diarrhea.
In dentistry, used to add toughness and opacity to porcelain teeth.
Other common names for hydrated aluminum silicate include heavy or light kaolin, china clay, bolus alba, porcelain clay, white bole, and argilla.

Kaolin is a hydrated aluminum silicate.
Aluminium silicate occurs naturally as a clay that is prepared for pharmaceutical purposes by washing with water to remove sand and other impurities.
Aluminum Silicate is white filler that consist of silicon dioxide and aluminum oxide.

Aluminium silicate is used as a white pigment in paints, printing inks and paper, where it acts as a partial substitute for titanium dioxide and increases the opacity, brightness of the product.
Aluminium silicate is used as white filler in rubber as it provides good reinforcing properties, tensile strength, hardness, process stability, electrical & heat properties and Ultimate performance.
Aluminium silicate, also referred to as aluminum silicate, is a compound made from aluminum, oxygen and silicate that can take the form of a mineral as well as combine with water to make a clay.

Aluminium silicate has a hardness of 1-2 on the Mohs scale of mineral hardness.
The refractive index of aluminium silicate is 1.56 and the density is 2.8 to 2.9 g/cm.
Aluminum silicate comes in three mineral forms: andalusite, kyanite and sillimanite, all of which have the chemical formula Al2SiO5 but have distinct crystal structures.

Another compound, Aluminium silicate, is a garnet known as pyrope when found in the mineral form, and is considered to be the only garnet that is always red.
Aluminium silicate refers to materials containing anionic Si-O-Al linkages.
Commonly, the associate cations are sodium (Na+), potassium (K+) and protons (H+).

Such materials occur as minerals and as synthetic materials, often in the form of zeolites.
Both synthetic and natural Aluminium silicates are of technical significance as structural materials, catalysts, and reagents.
Aluminum silicate is used to prepare aluminum-silicate polymer composite (PASiC), which is an inorganic coagulant used in water treatment.

Aluminium silicate is used as a catalyst for the pyrolysis of rice husk to crude bio -oil, which upgraded to supercritical ethanol.
Aluminium silicate is used as filler in paper, rubber and in paints.
Aluminium silicate Jet Fiber Blanket has the advantages of high-temperature resistance, good thermal stability, low thermal conductivity, small heat capacity, good resistance to mechanical vibration, small thermal expansion, and good thermal insulation performance.

Aluminium silicate can be woven into aluminum silicate fiberboard and other products.
Aluminium silicate is also a new type of material to replace asbestos, widely used in metallurgy, electric power, machinery, and chemical thermal equipment for heat preservation.
A native hydrated aluminium silicate, freed from most of its impurities by elutriation and dried.

The article of commerce may be further specified as to chloride, foreign substances, particle size, loss on drying, loss on ignition and pH value.
Aluminium silicate is an insecticide and insect repellent.
Aluminium silicate has a low mammalian toxicity.

Aluminium silicate is virtually insoluble in water and in many organic solvents.
Little data has been published regarding its environmental fate.
Aluminium silicate is moderately toxic to fish and honeybees.

Aluminium silicate (or aluminum silicate) is a name commonly applied to chemical compounds which are derived from aluminium oxide, Al2O3 and silicon dioxide, SiO2 which may be anhydrous or hydrated, naturally occurring as minerals or synthetic.
Their chemical formulae are often expressed as xAl2O3·ySiO2·zH2O.
Aluminium silicate is known as E number E559.

Aluminium silicate is a compound made from aluminium, oxygen and silicate that can take the form of a mineral as well as combine with water to make clay.
Aluminium silicate comes in three mineral forms: andalusite, kyanite and sillimanite, all of which have the chemical formula Al2SiO5 but have distinct crystal structures.
When magnesium aluminium silicate is hydrated it becomes a clay known as kaolin, which is used for treating ailments such as diarrhoea and to combat diaper rash as well as rashes from poison oak and poison ivy.

When combined with magnesium and hydrated, the result is a clay mixture that sees common use in antacids as well as a thickener for cosmetics and other beauty products.
Aluminium silicate also appears as an inactive ingredient for deodorants.
The kyanite form of aluminium silicate is used to create mullite for industrial use, and this compound is used by the ceramics industry as a refractory, as well as to manufacture electrical insulating materials and heating elements.

The sillimanite form is used in such industries as glass-making, metal smelting and in iron foundries.
Aluminium silicate has also been used topically as an emollient and drying agent.
Specifically, Aluminium silicate has been used to dry oozing and weeping poison ivy, poison oak, and poison sumac rashes.

Aluminium silicate has also been used as a protectant for the temporary relief of anorectal itching and diaper rash.
Aluminium silicate (or aluminium silicate) is a name commonly applied to chemical compounds which are derived from aluminium oxide, Al2O3 and silicon dioxide, SiO2 which may be anhydrous or hydrated, naturally occurring as minerals or synthetic.
Their chemical formulae are often expressed as xAl2O3.ySiO2.zH2O These include the compounds:-; Al2SiO5, (Al2O3.SiO2), which occurs naturally as the minerals andalusite, kyanite and sillimanite which have different crystal structures.

Aluminium silicate, which occurs naturally as the mineral kaolinite and is also called aluminium silicate dihydrate.
Aluminium silicate is a fine white powder and is used as a filler in paper and rubber and also used in paints.
Aluminium silicate, called metakaolinite, formed from kaolin by heating at 450°C (842°F).

Aluminium silicate, the mineral mullite, the only thermodynamically stable intermediate phase in the Al2O3-SiO2 system at atmospheric pressure
Aluminium silicate is used as an over the counter antacid for the self-treatment of heartburn, sour stomach, or acid indigestion Label.
Aluminium silicate is either a naturally occurring mineral clay or an artificially synthesised complex mineral excipient composed of magnesium, aluminium, silicon, oxygen, and water.

Aluminium silicate is chemically described as a polymeric complex made up of layers of alumina and silica sheets.
Other elements may be present, such as iron, lithium, calcium and carbon.
Aluminium silicate is supplied in the form of an off-white to creamy-coloured, odourless and tasteless micronised or flaky powder.

Aluminium silicate manufactured and supplied by us is a mixture of aluminum, silica, and oxygen that can be either a mineral, or combined with water to form clay.
Aluminium silicate is light weight and super white in color.
Aluminium silicate is having high degree of brightness, low plasticity, ease of dispersion and good oil absorption reduction.

Minerals composed of aluminium silicate include ​Andalusite, Sillimanite (or Bucholzite) and Kyanite.
Aluminium silicate is a compound made from aluminum, oxygen and silicate that can take the form of a mineral as well as combine with water to make a clay.
Aluminum silicate comes in three mineral forms: andalusite, kyanite and sillimanite, all of which have the chemical formula Al2SiO5 but have distinct crystal structures.

When magnesium aluminum silicate is hydrated it becomes a clay known as kaolin, which is used for treating ailments such as diarrhea and to combat diaper rash as well as rashes from poison oak and poison ivy.
When combined with magnesium and hydrated, the result is a clay mixture that sees common use in antacids as well as a thickener for cosmetics and other beauty products.
Aluminium silicate also appears as an inactive ingredient for deodorants.

The kyanite form of aluminium silicate is used to create mullite for industrial use, and this compound is used by the ceramics industry as a refractory, as well as to manufacture electrical insulating materials and heating elements.
Aluminium silicate (aluminum oxide silicate), under the brand name Adsorbin among others, is used as antidiarrheal agent and intestinal adsorbent.
Aluminium silicate has traditionally been used internally to control diarrhea.

Aluminium silicate has also been used topically as an emollient and drying agent.
Aluminium silicate has also been used as a protectant for the temporary relief of anorectal itching and diaper rash.
Aluminium silicate, in blends with other compounds, is supplied either in a paste or a liquid.

Aluminium silicate is chiefly used in the auto trade for scratch removal, rubbing and polishing either by body shops or for pre sale renovation in the used car trade, but can also be found in retail products as well.
Glazing compounds are often used after scratch removal.
Away from automotive applications aluminium silicate can be found in a wide range of cleaning and polishing applications such as hard and soft surface household and industrial cleaners and polishes, liquid cleaners and polishes for precious metals, all round retail products and hand cleaners.

form: fibers
PH: 4-5

Aluminum Silicate is generally immediately available in most volumes.
Ultra high purity and high purity compositions improve both optical quality and usefulness as scientific standards.
Nanoscale elemental powders and suspensions, as alternative high surface area forms, may be considered.

American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
Typical and custom packaging is available, as is additional research, technical and safety (MSDS) data.
Aluminium silicate, also known as coal slag is a dispensable abrasive which is a by-product of coal-fired electric power generation plants.

Aluminum Silicate generates less dust than copper slag and is mainly used in open blasting operations in the oil- and shipyard industry.
Aluminum Silicate also referred to as aluminum silicate, is a compound made from aluminum, oxygen and silicate that can take the form of a mineral as well as combine with water to make clay.
Aluminum Silicate has a hardness of 1-2 on the Mohs scale of mineral hardness.

The refractive index of Aluminum Silicate is 1.56 and the density is 2.8 to 2.9 g/cm.
Aluminium silicate comes in three mineral forms: andalusite, kyanite and sillimanite, all of which have the chemical formula Al2SiO5 but have distinct crystal structures.
Another compound, magnesium aluminum silicate, is a garnet known as pyrope when found in the mineral form and is considered to be the only garnet that is always red.

Sodium aluminosilicate contains water and is referred to as synthetic sodium aluminosilicate, which manufacturers add to powdered foods to prevent lump formation.
Aside from its use in medicine, Aluminum Silicate also has industrial uses.
The ceramics industry uses it to produce fine porcelain, for example.

Aluminum silicate can be hydrated, or have water molecules associated with it.
In this case, it forms a clay.
Aluminum Silicate is the term for a group of clay minerals with the chemical formula of Al2O3.2SiO2.2H20.

Aluminum Silicate forms a layer of two alternating crystals — one of silicon-oxygen and one of alumina.
Aluminum Silicate is the main constituent of kaolin.
Aluminum Silicate has been used for many years to control diarrhea and to dry poison ivy and poison oak rashes.

Aluminum Silicate has also been used to treat diaper rash.
Commercially, it has been important in the ceramics industry, particularly for the production of fine porcelain.
Aluminum Silicate is also used to manufacture cement, bricks, and insulators, among other things.

Another aluminum silicate compound found as a mineral and as a clay is magnesium aluminum silicate, which is composed of magnesium, aluminum, silica, and oxygen.
In its mineral form, it is a type of garnet called pyrope.
Aluminum Silicate is often used as a gemstone, and is the only garnet to always be red in color.

Aluminum Silicate is chemical formula is Mg3Al2(SiO4)3, although there are frequently trace amounts of other elements present.
The hydrated form of magnesium aluminum silicate is a mixture of clays.
This purified mixture is commonly used as an antacid.

Aluminum Silicate is also used as a thickener in beauty products and cosmetics, and as an inactive ingredient in deodorants.
Sodium aluminum silicate is also referred to as sodium aluminosilicate and is composed of sodium, aluminum, silica, and oxygen.
Two minerals of this type are albite and jadeite.

Albite has the chemical formula of NaAlSi3O8, while that of jadeite is NaAlSi2O6.
There is an industrial form of sodium Aluminum Silicate, known as synthetic amorphous sodium aluminosilicate, that contains water.
This is a series of compounds and does not have a fixed chemical composition.

Aluminum Silicate is used as an additive in powdered foods to keep lumps from forming.
Aluminum Silicate is also known as kaolin, or hydrated aluminum silicate when in powder form.
Aluminum silicate is a mixture of alumina, silica, and oxygen. Kaolin is often used as a demulcent and adsorbent in the pharmaceutical industry.

Aluminum Silicate is used in colour lakes (insoluble dyes).
As a raw material, it is commonly found in paper, plastics, cosmetics, and pharmaceuticals, and it is also used in pharmaceutical preparations as a filtering agent to clarify liquids.
As a medicinal agent, Aluminum Silicate is used to treat diarrhoea.

In dentistry, used to add toughness and opacity to porcelain teeth.
Other common names for hydrated aluminum silicate include heavy or light kaolin, china clay, bolus alba, porcelain clay, white bole, and argilla.
Aluminum silicate, also known as aluminium silicate, is a mixture of aluminum, silica, and oxygen that can be either a mineral or combined with water to form a clay.

Aluminum Silicate can also combine with other elements to form various other minerals or clays.
Some of these forms are used medicinally and industrially.
They retain their strength at high temperatures — a property known as being refractory.

Aluminum Silicate comes in three different forms — kyanite, andalusite, or sillimanite.
They all have the chemical formula Al2SiO5, but they have different crystal structures.
All three forms are rarely found in the same rock, because each occurs under different conditions of pressure and temperature.

Only kyanite and sillimanite are used industrially.
Aluminum Silicate is unusual in that its hardness varies, depending on the direction of the crystals.
Some of the crystals are similar to blue sapphires and are used as gemstones.

Aluminum Silicate is also used in the making of the frequently used industrial compound mullite.
This compound has the chemical formula 3Al2O3.2SiO2.
Aluminum Silicate is used as a refractory in the ceramics industry and in the manufacture of many things, including high voltage electrical insulations, glass, and heating elements.

Sillimanite can also be used as a refractory.
Aluminum Silicate is used in a variety of industries.
These include glass-making, ceramics, cement, iron foundries, and metal smelting.

Aluminum silicate can be hydrated or have water molecules associated with it.
In this case, it forms clay.
Aluminum Silicate is the term for a group of clay minerals with the chemical formula of Al2O3.2SiO2.2H20.

Aluminum Silicate forms a layer of two alternating crystals — one of silicon-oxygen and one of alumina.
Aluminum Silicate is the main constituent of kaolin.
Aluminum Silicate has been used for many years to control diarrhoea and to dry poison ivy and poison oak rashes.

Aluminum Silicate has also been used to treat diaper rash.
Commercially, Aluminum Silicate has been important in the ceramics industry, particularly for the production of fine porcelain.
Aluminum Silicate is also used to manufacture cement, bricks, and insulators, among other things.

Another aluminum silicate compound found as a mineral and as clay is magnesium aluminum silicate, which is composed of magnesium, aluminum, silica, and oxygen.
In its mineral form, it is a type of garnet called pyrope.
Aluminum Silicate is often used as a gemstone and is the only garnet to always be red in colour.

Aluminum Silicate is chemical formula is Mg3Al2(SiO4)3, although there are frequently trace amounts of other elements present.
Aluminum Silicate is hydrated it becomes a clay known as kaolin, which is used for treating ailments such as diarrhea and to combat diaper rash as well as rashes from poison oak and poison ivy.
When combined with magnesium and hydrated, the result is a clay mixture that sees common use in antacids as well as a thickener for cosmetics and other beauty products.

Aluminum Silicate also appears as an inactive ingredient for deodorants.
A type of clay mineral that works as a nice helper ingredient to thicken and stabilize formulas.
As a clay, it consists of platelets that have a negative charge on the surface (face) and a positive on the edge.

So the face of one platelet attracts the edge of the other and this builds a so-called "house of card" structure meaning that Magnesium Aluminum Silicate (MAS) thickens up products and helps to suspend non-soluble particles such as color pigments or inorganic sunscreens (zinc oxide and titanium dioxide).
Certain types of aluminium silicate minerals are known as zeolites.
Zeolites have a porous structure with channels and cavities that can accommodate water molecules and certain ions.

They are used in applications such as ion exchange, water softening, and as catalysts in various chemical processes.
Aluminum Silicate minerals, particularly kaolinite, can act as absorbents.
Due to their porous nature, they are used in the production of absorbent products, including cat litters and industrial absorbents for liquids.

Aluminum Silicate is used in the pharmaceutical and cosmetic industries for its properties as an absorbent and bulking agent.
Aluminum Silicate can be found in various products such as face masks, powders, and certain medications.
Aluminum Silicate minerals may be used in agriculture as soil conditioners.

They can improve the structure of the soil, increase water retention, and enhance nutrient availability to plants.
Zeolites, which fall under the category of aluminium silicate minerals, are used in environmental applications such as wastewater treatment and air purification.
Their ion exchange properties make them effective in removing contaminants from water and air.

Feldspar, a type of aluminium silicate mineral, is a common component in the production of glass.
Aluminum Silicate contributes to the glass's composition, influencing its melting point and other properties.
Certain aluminium silicate minerals are valued as gemstones.

For example, Aluminum Silicate is sometimes used as a gemstone in jewelry.
Aluminum Silicate minerals, particularly those with high-temperature stability such as kaolinite, are used in the production of insulating materials, including firebrick and refractory ceramics.
Certain aluminium silicate minerals, such as montmorillonite, are used in drilling fluids in the oil and gas industry to improve the stability of boreholes and facilitate drilling processes.

Some aluminium silicate minerals are used as extenders in paint and coatings, contributing to their texture and consistency.
Aluminum Silicate, due to its white color and fine particle size, is used in the formulation of artist's paints and pastels.
Some aluminium silicate minerals are used as ornamental stones or in the production of jewelry due to their attractive colors and patterns.

Uses:
Aluminum Silicate can be used to prepare poly(methyl methacrylate) (PMMA) based nanocomposite materials.
The kyanite form of aluminium silicate is used to create mullite for industrial use, and this compound is used by the ceramics industry as a refractory, as well as to manufacture electrical insulating materials and heating elements.
The sillimanite form is used in such industries as glass-making, metal smelting and in iron foundries.

Aluminium silicate minerals can be used in the formulation of adhesives and sealants, contributing to their binding and sealing properties.
Aluminum Silicate minerals are sometimes incorporated into construction materials such as bricks, tiles, and cement, providing specific properties such as strength and durability.
Certain aluminium silicate minerals, particularly those with absorbent properties, can be used in the formulation of oil absorbents for spill cleanup in industrial and environmental settings.

Aluminum Silicate, a subgroup of aluminium silicate minerals, are used as catalysts in various chemical processes due to their porous structure and ion-exchange capabilities.
Aluminum Silicate minerals can be used as foundry sands in metal casting processes, providing a refractory material that can withstand high temperatures.
Aluminum Silicate minerals are used in the production of electrical insulators due to their high dielectric strength and thermal stability.

Aluminium silicate minerals, particularly those with pharmaceutical-grade purity, may be used as excipients in pharmaceutical formulations to improve the consistency and flow properties of tablets and powders.
Aluminum Silicates, with their ion-exchange properties, are employed in water filtration systems to remove certain ions and impurities from water.
Aluminium silicate minerals can be used in the production of geopolymers, which are alternative binders for construction materials with lower environmental impact compared to traditional cement.

Aluminium silicate minerals, when finely ground, can serve as soil amendments to improve soil structure and nutrient availability in agriculture.
Certain aluminium silicate minerals are used in cosmetics as exfoliating agents, helping to remove dead skin cells and improve the texture of the skin.
Aluminum Silicates, being stable under various conditions, are used as catalyst supports in industrial catalytic processes.

Aluminum Silicate and other aluminium silicate minerals are used in paper coating to enhance printability, smoothness, and brightness of paper products.
Aluminum Silicates are utilized as molecular sieves in various applications, such as drying gases and liquids, due to their ability to selectively adsorb certain molecules.
Aluminum Silicate contains water and is referred to as synthetic sodium aluminosilicate, which manufacturers add to powdered foods to prevent lump formation.

Aluminium silicate minerals, such as kaolinite, are crucial components in the ceramics industry.
They contribute to the formation of clay bodies, which are shaped and fired to create pottery, tiles, and porcelain.
Andalusite, kyanite, and sillimanite, all aluminium silicate minerals, are used in the production of refractory materials.

These materials are resistant to high temperatures and are employed in applications like furnace linings, kiln furniture, and crucibles.
Aluminum Silicate minerals known as zeolites are utilized for ion exchange.
Aluminum Silicates have a porous structure that allows them to trap and release ions.

They are used in water softening, catalysis, and as adsorbents in various industrial processes.
Aluminum Silicate, with its absorbent properties, is employed in the production of absorbent products such as cat litters, industrial absorbents for liquids, and certain pharmaceutical and cosmetic formulations.

Feldspar, an aluminium silicate mineral, is a common ingredient in the production of glass.
Aluminum Silicate helps reduce the melting point of the glass, making it easier to form and shape.
Aluminium silicate minerals can serve as soil conditioners in agriculture.

They improve soil structure, water retention, and nutrient availability, contributing to enhanced plant growth.
Aluminum Silicates, which fall under the category of aluminium silicate minerals, are used in environmental applications, including wastewater treatment and air purification, due to their ion exchange and adsorption properties.
Aluminum Silicate, a type of aluminium silicate mineral, is used in drilling fluids in the oil and gas industry to stabilize boreholes and assist in drilling processes.

Aluminium silicate minerals, particularly those with high-temperature stability, are used in the production of insulating materials for applications like firebrick, refractory ceramics, and insulation.
Aluminum Silicate minerals are used as extenders in paint and coatings.
They contribute to the texture, consistency, and performance of these materials.

Certain aluminium silicate minerals, like andalusite, are used as gemstones in jewelry.
Others are used as ornamental stones due to their attractive colors and patterns.
Aluminum Silicate minerals, such as kaolinite, can be used in the production of paper and textiles as fillers to improve the materials' physical properties.

Aluminum Silicate is used in pharmaceuticals and cosmetics for its absorbent and bulking properties.
Aluminum Silicate can be found in products such as face masks, powders, and certain medications.
Aluminum Silicates, especially kaolinite, are used in the formulation of artist's paints, pastels, and other art and craft materials.

Some aluminium silicate minerals, such as zeolites, are used as additives in animal feeds.
They can help improve digestion, reduce ammonia emissions, and act as a binder for pelleted feeds.
Aluminum Silicate minerals with low thermal conductivity, such as certain types of clay minerals, can be used in the production of thermal insulation materials.

Aluminium silicate minerals are sometimes used in the formulation of grinding and polishing compounds for various materials, including metals and ceramics.
Aluminum Silicates, due to their well-defined pore structures and ion-exchange properties, are employed as catalysts in chemical reactions.
They find applications in petrochemical processes, environmental catalysis, and more.

Certain aluminium silicate minerals can be used as additives in concrete to improve its properties, such as strength, durability, and resistance to cracking.
Aluminum Silicates, especially those with unique properties like high hardness and resistance to wear, are used in the production of high-performance ceramics for industrial applications.
Aluminum Silicates may be used as fillers in dental materials, contributing to the strength and stability of dental composites and cements.

Aluminum Silicates can be used in gardening and horticulture to improve soil structure, water retention, and nutrient availability for plants.
Aluminum Silicates, with their ability to adsorb and exchange ions, are used in septic tank additives to enhance the breakdown of organic matter and control odors.
Aluminum Silicates can act as fire retardants in various materials, helping to reduce flammability and enhance fire resistance.

Aluminum Silicates, when appropriately processed, can be used as abrasives for grinding and polishing applications.
Aluminum Silicate, a type of aluminium silicate, is used in oil-well drilling fluids to control viscosity and provide lubrication during drilling operations.
Aluminum Silicates are employed in chemical filtration processes to selectively remove specific molecules or ions from liquids or gases.

Some Aluminum Silicates may be used as food additives, serving various purposes such as anticaking agents or clarifying agents in beverages.
Aluminum Silicates can be used in the conservation and restoration of archaeological artifacts, helping to stabilize and protect cultural heritage materials.

Safety Profile:
Inhalation of fine dust or respirable crystalline silica generated during the mining, processing, or handling of certain aluminium silicate minerals can pose a risk to respiratory health.
Aluminum Silicate dust is a known respiratory hazard and can cause lung diseases, including silicosis.
Direct contact with certain aluminium silicate minerals, particularly in the form of dust or powder, may cause skin and eye irritation.

Aluminum Silicate's important to use personal protective equipment (PPE) such as gloves and goggles when handling these materials.
Prolonged or repeated exposure to certain aluminium silicate minerals may lead to sensitization in some individuals, resulting in allergic reactions upon subsequent exposure.

ALUMINIUM STEARATE
Aluminum Stearate is an aluminum salt of stearic acid.
Aluminum Stearate is the aluminum salt of the fatty acid, stearic acid.
Aluminium Stearate is an aluminium salt.
Aluminium Stearate contains an octadecanoate.


CAS Number: 7047-84-9 / 637-12-7
EC No.: 211-279-5 / 230-325-5
MDL Number: MFCD00036389
Linear Formula: Al(C18H35O2)3
Compound Formula: C54H105AlO6


Aluminium Stearate or (aluminum tristearate) is a white coloured powder, wax – like powder (metallic soap) that dissolves well in vegetable oils upon heating.
Aluminium Stearate is soluble in glycol, alkali, BTX, chlorinated hydrocarbons.
If aluminium stearate is in high concentration, gelling can be seen upon cooling.


Aluminium Stearate exhibits the following properties: good gelling and thickening action, excellent water repellence, transparency and a synergistic effect with zinc stearate or calcium stearate.
Aluminium stearate exhibits a relatively high solubility in hydrocarbon solvents (such as mineral spirits) when compared to other metallic stearates.


Aluminium Stearate is insoluble in water, alcohol and ether; but when hot, it is readily soluble in benzene, acids and common solvents.
Aluminum Stearate is a fine white powder generally used for its lubricating and emulsion stabilizing properties.
Its hydrophobic nature makes Aluminium Stearate a good thickener and coating ingredient in several cosmetic applications.


Aluminum Stearate is one of numerous organo-metallic compounds sold by American Elements for uses requiring non-aqueous solubility such as recent solar energy and water treatment applications.
Similar results can sometimes also be achieved with Nanoparticles and by thin film deposition.


Note American Elements additionally supplies many materials as solutions.
Aluminum Stearate is generally immediately available in most volumes.
High purity, submicron and nanopowder forms may be considered.


Aluminium Stearate is highly hydrophobic and feature outstanding transparency and excellent adhesion to metal surfaces.
Aluminium Stearate exhibits relatively high solubility in hydrocarbon solvents compared to other metallic stearates.
Aluminium Stearate is insoluble in water, alcohol and ether; but is readily soluble in benzene, acids and common solvents when hot.


Aluminium Stearate exhibits good gelling and thickening properties, excellent transparency and a synergistic effect with Zinc Stearate or Calcium Stearate.
Aluminum stearate (aluminum distearate) is a white, wax-like powder (metallic soap) that dissolves in mineral spirits or hot oil.
Aluminium Stearate is a small amount (2% or less) added to oil paint imparts a short, buttery consistency.


Aluminium Stearate eliminates the separation of pigment and oil, thickens varnishes considerably.
A concentrate of aluminum stearate and linseed oil can be prepared ahead of time and added to the paint whenever needed.
Aluminum stearate has long storage life if stored in cool and dry location.


Aluminum Stearate (C54H105AlO6) exists as white powder and is an aluminum salt of stearic acid.
According to the FDA, Aluminium Stearate is considered safe for general or specific, limited use in food.
Aluminium Stearate is not classifiable as a human carcinogen (cancer-causing agent).


Colourants ensure an appealing appearance of the cosmetic product and serve for the embellishment of the skin and hair.
The most frequently used colourants are synthetic; only a few natural substances are available.
For colourants, the applicable INCI names are in most cases the so-called Colour Index Numbers, the "CI Numbers".


A hard, thermoplastic white powder prepared from Tallow and Alum. Aluminum stearate forms gels with turpentine, Mineral spirits, and oils.
Aluminum stearate is an aluminum salt of stearic acid that functions as a thickening agent and helps stabilize products.
Types of aluminum stearates, generally classified as aluminum mono-, di-, and tri-stearate.


They vary in terms of physical properties such as melting point, free fatty acids, and particularly the gelling properties.
Oils with a low viscosity are best thickened by aluminum di- and tri-stearate, whilst very viscous oils from stiffer gel when combined with aluminum mono- or di-stearates.



USES and APPLICATIONS of ALUMINIUM STEARATE:
Aluminium Stearate is used Paint and varnish drier, greases, waterproofing agent, cement additive, lubricants, cutting compounds, flatting agent, and cosmetics.
Relevant identified uses of Aluminium Stearate:
pharmaceuticals, defoaming agent in beet sugar and yeast processing.


Aluminium Stearate is used in foods as a buffer, firming agent and neutralising agent.
Aluminium Stearate is used as a thickener in paints, inks and greases; a water repellent for leather and rope; and a lubricant in plastics and rope.
Aluminium Stearate is also used in cement production for waterproofing and air entrainment, and in hot-melt paper coating compounds.


Because of its unusually heavy bodying properties, Aluminium Stearate is used in the manufacture of paints, inks, greases, and waxes.
In recent years, hydrophobic Aluminium Stearate was tested as a low-solubility denitrification substrate for anaerobic bacteria and a source of aluminum for phosphate precipitation.


Aluminum stearate has potential for use in a flow-through container for denitrification of oxidized effluent from home sewage systems.
Aluminium Stearate was also referred that the preheated mixture of metal soaps, along with the costabilizer, delayed the fast blackening of the polymer, but mainly showed a reduction.


Aluminium distearate is the most commonly used grade of aluminum stearate.
Aluminum Stearate is mainly used in the formulation of makeup products such as eyeliner, mascara, lipsticks, mascara, face powders, and foundations.
Aluminum stearate is made via the precipitation process using high quality stearic acid and exhibits the following properties: Good gelling and thickening action, excellent water repellency, transparency and a synergistic effect with zinc stearate or calcium stearate.


Due to their water repellency Aluminium Stearate is used as hydrophobic agents in the building industry.
Aluminium Stearate is used as a lubricant in the production of polyamides and thermosetting plastics.
Aluminium Stearate is also used as a thickening agent in the production of varnishes and lacquers.


The effects of metal soaps on pigments have been extensively studied.
Aluminum stearate was found to coat the surface of pigment particles and helped prevent settling as well as reducing the amount of oil needed to wet the pigment.
The amount of aluminum stearate needed to coat pigments varied on a weight basis, but a solution of 2% by weight (weight of aluminum stearate/weight of oil) of aluminum stearate was more effective than 0.5% or 4% solutions in altering pigment surfaces.


The soaps coat the surface of the pigments and by steric effects keep the particles from aggregating, which helps to keep the particles in suspension.
With increasing amounts of aluminum stearate the oil pigment mixture becomes viscous, and by using an appropriate amount of aluminum stearate the paint can gel at a lower pigment concentration.


This can be used to create a "cheaper" paint since a smaller amount of a costly pigment needs to be used.
A significant advantage of using stearates is that the oil and pigment do not separate greatly over long periods of time in the paint tube.
Manufacturers of artists' paints often use aluminum stearate in their formulations without listing it as a component on the product label.


In the pharmaceutical industry, Aluminium Stearate is used as an anticaking agent; colorant; emulsion stabilizer; and viscosity increasing agent.
Aluminium Stearate has been used as a Drier, thickener, Emulsifier, and matting agent in paints and varnishes although excess amounts produce soft, noncohesive films.
Aluminum stearate is also used to waterproof fabrics, ropes, Paper, Leather, Concrete, and Stucco.


Aluminium Stearate is used as an ingredient in photographic emulsions.
Occurrence in cosmetics: Oleogels, creams and ointments, powders
Aluminum Stearate are highly hydrophobic, and feature outstanding transparency and excellent adhesion to metal surfaces.
Due to their water repellency, aluminum di- and tri-stearate are used as hydrophobic agents in the building industry.


-Plastics Industry:
Metallic stearates, which have been used primarily as acid scavengers, lubricants and release agents by the plastics industry, are becoming increasingly important in melt processing.
In addition to optimizing production, the use of metallic stearates allows the processor to produce finished articles with smoother surfaces and lower friction.
Metallic stearates are mainly produced from organic raw materials.
Therefore, they tend to degrade to some degree when exposed to excessively high temperatures, resulting in discoloration.
Fanchem has developed a range of thermostable metallic stearates, which are highly resistant to discoloration when used in transparent or brightly colored thermoplastics even at high processing temperatures


-Cosmetics Industry:
Aluminium stearate is used as an emulsifier in cosmetics.
They are used for their lubricating properties.
The stearate salts also increase the thickness of the oil portion of cosmetics and personal care products.
Hence, finished cosmetics products are typically not transparent.


-Paint Industry:
Aluminium stearate is used as a thickener in Varnishes/Lacquers, an anti-settling agent for pigmentation, as a pigment suspension, and an agent to improve water resistance and gloss.
Aluminium Stearate is useful as a water repellent agent, a hydrophobic agent, and a waterproof agent in the paint industry.
Aluminum stearate is a white powder soluble in oils and insoluble in water and alcohol.
Aluminium Stearate is used as a lubricant in the production of polyamides and thermosetting plastics, a thickening agent in production of varnishes and lacquers, a water repellent agent and hydrophobic agent, a paint drier and a defoaming agent.


-GREASES, LUBRICATING OILS:
Aluminium Stearate gives excellent properties of transparency, stringiness and water repellency.
Aluminium Stearate acts as a high temperature resistant when added in lubricants.
Aluminium Stearate is used by ONGC for defoaming properties.


-DRY LUBRICATION :
Aluminium Stearate is useful as a lubricant in metals processing, such as wire drawing, producing brighter products.
-Occurrence in other products:
In many industries as thickener, matting agent additive and for the hydrophobic treatment of absorbent materials such as paper, textiles and concrete


-PAINTS, VARNISHES AND LACQUERS :
Aluminium Stearate is adequate for improving pigments suspension, control of viscosity and gloss, water resistance and improving brushing and penetration.
Aluminium Stearate finds very wide application in paint industries for preparation of enamels and lacquers where it acts as thickening agent or suspending agent.
Aluminium Stearate reduces sagging and setting of pigment and works as varnish drier.
Aluminium Stearate is used as an important ingredient for water proofing in tarpaulin & textile industrie.


-PRINTING INKS :
The high gelling properties of Aluminium Stearate are useful for thickening and suspension improving
-PLASTICS :
Aluminium Stearate is used in as a lubricant in the production of Polyamides and Thermosetting plastics.


-RUBBER :
Aluminium Stearate is used as dusting powders to prevent sticking of unvulcanised rubber sheet.
-CONSTRUCTIONS :
Aluminium Stearate is recommended jointly with Calcium Stearate for improving the water resistance of concrete and cements.



FUNCTIONS OF ALUMINIUM STEARATE IN COSMETIC PRODUCTS:
*ANTICAKING
Prevents powdered products from caking / sticking together
*COLORANT
Colours cosmetic products, skin, nails and / or hair
*EMULSION STABILISING
Supports emulsion formation and improves product stability
*VISCOSITY CONTROLLING
Increases or decreases the viscosity of cosmetic products



WHAT DOES ALUMINIUM STEARATE DO IN A FORMULATION?
*Anticaking
*Cosmetic colorant
*Emulsion stabilising
*Viscosity controlling



MANUFACTURING PROCESS OF ALUMINIUM STEARATE:
Aluminium stearate is synthesised via the precipitation process using high quality stearic acid.
This is done by adding aluminium isopropoxide to stearic acid in anhydrous pyridine, inducing the precipitation of the pyridine complex.
Pyridine is then removed under vacuum to give the aluminium stearate.
Aluminium stearate is a fine, bulky, odourless and colourless powder forming a plastic mass when heated, having the properties both of organic and inorganic matter.
Aluminium Stearate embraces most of the characteristics of other metallic stearates and is regarded as the most important of these. Several studies of the material have already appeared in past years.



FUNCTIONS OF ALUMINIUM STEARATE:
*Anti-caking agent: Ensures the fluidity of solid particles and limits their agglomeration in cosmetic products in powder or hard mass
*Cosmetic colorant: Colors cosmetics and/or imparts color to skin
*Emulsion Stabilizer: Aids the emulsification process and improves emulsion stability and shelf life
*Viscosity control agent: Increases or decreases the viscosity of cosmetics



SOLUBILITY OF ALUMINIUM STEARATE:
Aluminum stearate exhibits relatively high solubility in hydrocarbon solvents (such as mineral spirits) when compared to other metallic stearates.
Aluminium Stearate is insoluble in water, alcohol and ether; but is readily soluble in benzene, acids and common solvents when hot.



TOW TO USE ALUMINIUM STEARATE:
Aluminum stearate dissolves in vegetable oils on heating and if a high enough concentration of the soap is used, gelling occurs on cooling.
In the usual practice of making paints, the aluminum stearate is ground with the pigment before the bulk of the oil is added.
To prepare a concentrated solution (10% w/v), add 100 grams of aluminum stearate (nearly fills a half liter measuring cup without compacting) to one liter of linseed oil.
Heat the oil to about 150° C. and gradually slowly adding the white powder to the hot oil with stirring.
Add one part of this solution to four parts of oil by weight of oil before adding to pigments and grinding.



BACKGROUND INFORMATION ON ALUMINIUM STEARATE USE IN COSMETICS:
Aluminium stearates are fatty acid salts (so-called metal soaps).
With oils and liquid paraffin they form gels which can serve as a cream basis.
Oleo gelling agents such as aluminium stearate are, therefore, used as thickening agents in liquid hydrophobic (water-repellent) phases.
They are a basic ingredient in oleogels on the basis of hydrocarbons, glycerides, polysiloxanes (silicones) or wax esters.
Moreover, they are used as swelling and thickening agents for cosmetic products and are applied, for instance, also for the production of astringent powders and creams (eg anti-perspirants).



ALUMINIUM STEARATE VS. CALCIUM STEARATE
The chemical is insoluble in water and remain stable under various extreme as well as ordinary conditions.
Aluminium Stearate is and inorganic chemical with a molecular formula (C17H35COO)3Al and is appreciated for the features such as high efficiency, purity and chemical compositions.
Aluminium Stearate is a white coloured powder.

Aluminium Stearate is the aluminium salt of stearic acid.
Aluminium Stearate is insoluble in water, alcohol and ether.
However, Aluminium Stearate is soluble in glycol, alkali, BTX, chlorinated hydrocarbons.

Aluminium Stearate dissolves well in vegetable oils on heating and if high concentration is used, on cooling gelling is seen.
Aluminium Stearate is used as an emulsifier in cosmetics.
Aluminium Stearate is also used as lubricant in polyamides and in thermosetting of plastics.
Its use as a water repellent agent and hydrophobic agent makes Aluminium Stearate useful to be used as a waterproofing agent in paint industry.

Aluminium stearate is used as thickening agent in production of varnishes and lacquers.
Aluminium Stearate also finds use as an anticaking agent in petroleum products.
Due to high reactivity, calcium oxide is handled, stored and packaged ensuring minimal atmospheric contact at our premises.

Calcium Stearate is an insoluble salt of calcium, stearic acid and palmatic acid.
In hard water, when soap of calcium ions is mixed, the scum that is formed is calcium stearate.
Calcium stearate is non-toxic and has many applications as stabilizer and lubricant.

Besides water, it is insoluble in water, ether, chloroform, acetone, cold alcohol as well.
However, it is slightly soluble when dissolved in hot alcohol, hot vegetable and mineral oil.
It shows good solublity in hot pyridine.

The use of calcium stearate is seen widely as a stabilizer for PVC resins and lubricant for plastic moulding powders or tablets.
Its use is recommended also in emulsions, cements, pencils, construction chemicals, paint flattening agent, resin coated sands and foundry chemicals, decaking agent in food items like onions and cosmetics.

Use of calcium stearate is seen as a lubricating agent in paper and paperboard coating compositions, iron wire drawing and leather cloth manufacturing as well.
Its use has been extended as a neutralizer, colour stabilizer, reducer of fiber breakage and de-agglomerator in PP and HDPE applications.
Calcium stearate is also known as octadecanoic acid calcium salt, stearic acid calcium salt.



PHYSICAL and CHEMICAL PROPERTIES of ALUMINIUM STEARATE:
Molecular Weight: 877.4
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 45
Exact Mass: 876.7726545
Monoisotopic Mass: 876.7726545
Topological Polar Surface Area: 120 Ų
Heavy Atom Count: 61
Formal Charge: 0
Complexity: 196
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 4
Compound Is Canonicalized: Yes
Compound Formula: C54H105AlO6
Molecular Weight: 877.38
Appearance: White Powder
Melting Point: 103-155 °C
Boiling Point: 2467°C @ 101.325 hPa
Density: 1.01 g/cm3
Solubility in H2O: N/A
Exact Mass: 876.772655
Monoisotopic Mass: 876.772655

Linear Formula: Al(C18H35O2)3
MDL Number: MFCD00036389
EC No.: 211-279-5
Pubchem CID: 12496
IUPAC Name: aluminum; octadecanoate
SMILES: [Al+3].[O-]C(=O)CCCCCCCCCCCCCCCCC.[O-]C(=O)CCCCCCCCC[O-]CCCCCCCC.C(=O)CCCCCCCCCCCCCCCCC
InchI Identifier: InChI=1S/3C18H36O2.
InchI Key: CEGOLXSVJUTHNZ-UHFFFAOYSA-K
Physical state: solid
Color: No data available
Odor: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility No data available
Partition coefficient: n-octanol/water: No data available

Vapor pressure: No data available
Density: 1,350 g/cm3
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Molecular Weight: 877.39
Molecular Formula: 3(C18H35O2)?Al
Boiling Point: 359.4ºC at 760 mmHg
Melting Point: 103ºC
Flash Point: 162.4ºC
Purity: N/A
Density: 1.01
Appearance: solid
Storage: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Hazard Codes: Xi
HS Code 2915709000
Log P: 18.76620
PSA: 78.9
Risk Statements: R36/37/38
RTECS: BD0707000
Safety Statements: S22-S24/25
Stability: Stable.



FIRST AID MEASURES of ALUMINIUM STEARATE:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ALUMINIUM STEARATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of ALUMINIUM STEARATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Special hazards arising from the substance or mixture
Nature of decomposition products not known.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of ALUMINIUM STEARATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Wash and dry hands.
*Body Protection:
Choose body protection in relation to its type.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ALUMINIUM STEARATE:
-Precautions for safe handling:
*Hygiene measures:
General industrial hygiene practice.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage class:
Storage class (TRGS 510): 13: Non Combustible Solids



STABILITY and REACTIVITY of ALUMINIUM STEARATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
Aluminum stearate
Aluminium stearate
637-12-7
aluminium tristearate
Aluminum octadecanoate
ALUMINUM TRISTEARATE
Aluminum(III) stearate
Alugel 34TN
Octadecanoic acid, aluminum salt
U6XF9NP8HM
Octadecanoic acid, aluminum salt (3:1)
Metasap XX
Tribasic aluminum stearate
Rofob 3
Monoaluminum stearate
Aluminum (III) stearate
Aluminum stearate (1:3)
Aluminum stearate, tribasic
HSDB 5733
EINECS 211-279-5
UNII-U6XF9NP8HM
Aluminium tristearate, pure
SA 1500
Dihydroxy(octanoato-O)aluminum
AI3-01515
aluminum;octadecanoate
Aluminum, dihydroxy(octadecanoato-O)-
aluminum trioctadecanoate
Tristearic acid aluminum
aluminium trioctadecanoate
ALUMINUMTRISTEARATE
ALUGEL 30DF
ALUGEL 34TH
Rashayan Aluminium Stearate
THOMPSON'S WATER SEAL
ALUMINUM STEARATE [II]
ALUMINUM STEARATE [MI]
DTXSID0027278
CHEBI:37867
ALUMINUM STEARATE [VANDF]
ALUMINUM TRISTEARATE [HSDB]
ALUMINUM TRISTEARATE [INCI]
ALUMINIUM STEARATE [WHO-DD]
MFCD00036389
AKOS015901563
DB11290
ALUMINIUM STEARATE [EP MONOGRAPH]
FT-0622241
Q447821
Aluminum octadecanoate
Aluminium trioctadecanoate
Octadecanoic acid, aluminum salt
Aluminum(III) stearate
aluminium tristearate
aluminum tristearate
Tribasic aluminum stearate
stearic acid, aluminum salt
Monoaluminum stearate
C18-H37-Al-O4
aluminium dihydroxy(octadecanato-O-)
aluminium dihydroxy(stearato)-
aluminum dihydroxy stearate
dihydroxyaluminium stearate
aluminium monostearate
dibasic aluminium stearate
aluminium stearate H.G.
Monoaluminum Stearate
Aluminum Distearate
Aluminum Tristearate
Stearic Acid aluminum salt
Octadecanoic Acid, Aluminum Salt
Aluminum Monostearate
alugel34tn; aluminum(iii)stearate
aluminumstearate(1:3)
metasapxx
monoaluminumstearate
Octadecanoicacid,aluminiumsalt
octadecanoicacid,aluminumsalt
rofob3
Aluminium Stearate
Aluminium octadecanoate
Aluminium tristearate
Aluminium salt
Aluminium tristearate
aluminium (tri) stearate
Aluminium stearate tech
Aluminium stearate white powder
aluminium octadecanoate
octadecanoate, Aluminium salt



ALUMINIUM STEARATE
Aluminum Stearate (C36 H71 Al O5) or Aluminum Di-Stearate is Wax like powder (metallic soap).
Aluminum stearate is a white, wax-like powder that dissolves mineral spirits or hot oil.
Aluminium Stearate or (aluminum tristearate) is a white coloured powder, wax – like powder (metallic soap) that dissolves well in vegetable oils upon heating.


CAS Number: 7047-84-9 / 637-12-7
EC No.: 211-279-5 / 230-325-5
MDL Number: MFCD00036389
Linear Formula: Al(C18H35O2)3
Compound Formula: C54H105AlO6


Aluminium Stearate is a white or slightly yellow powder, mainly used as a heat stabilizer and lubricant for PVC plastics, anti-settling agent and drier in the paint industry, waterproofing agent for fabrics, thickening agent for lubricating oil, etc.
Aluminium stearate exhibits a relatively high solubility in hydrocarbon solvents (such as mineral spirits) when compared to other metallic stearates.


Aluminium Stearate is insoluble in water, ethanol, ether, but soluble in solvents such as alkali, turpentine, mineral oil, petroleum, kerosene, and benzene.
Aluminum Stearate is a fine white powder generally used for its lubricating and emulsion stabilizing properties.
Its hydrophobic nature makes Aluminium Stearate a good thickener and coating ingredient in several cosmetic applications.


Aluminium Stearate is stable.
Aluminum Stearate is generally immediately available in most volumes.
High purity, submicron and nanopowder forms may be considered.


Aluminium Stearate eliminates the separation of pigment and oil, thickens varnishes considerably.
A concentrate of aluminum stearate and linseed oil can be prepared ahead of time and added to the paint whenever needed.
Aluminium Stearate is incompatible with strong oxidizing agents.


Aluminium Stearate exhibits the following properties: good gelling and thickening action, excellent water repellence, transparency and a synergistic effect with zinc stearate or calcium stearate.
Aluminium Stearate is an aluminium salt.


Aluminium Stearate contains an octadecanoate.
Aluminum stearate (aluminum distearate) is a white, wax-like powder (metallic soap) that dissolves in mineral spirits or hot oil.
Aluminium Stearate is a small amount (2% or less) added to oil paint imparts a short, buttery consistency.


Aluminium Stearate exhibits good gelling and thickening properties, excellent transparency and a synergistic effect with Zinc Stearate or Calcium Stearate.
A small amount of Aluminium Stearate (2% or less) added to oil paint imparts a short, buttery consistency.
Aluminium Stearate eliminates the separation of pigment and oil, thickens varnishes considerably.


Aluminum stearate has long storage life if stored in cool and dry location.
Aluminium Stearate exhibits relatively high solubility in hydrocarbon solvents compared to other metallic stearates.
Aluminium Stearate is insoluble in water, alcohol and ether; but is readily soluble in benzene, acids and common solvents when hot.


A concentrate of Aluminium Stearate and linseed oil can be prepared ahead of time and added to the paint whenever needed.
Aluminum Stearate (C54H105AlO6) exists as white powder and is an aluminum salt of stearic acid.
Colourants ensure an appealing appearance of the cosmetic product and serve for the embellishment of the skin and hair.


A hard, thermoplastic white powder prepared from Tallow and Alum. Aluminum stearate forms gels with turpentine, Mineral spirits, and oils.
Aluminium Stearate is made via the precipitation process using high quality stearic acid and exhibits the following properties: Good gelling and thickening action, excellent water repellency, transparency and a synergistic effect with zinc stearate or calcium stearate.


The effects of metal soaps on pigments have been extensively studied.
Aluminium Stearate is highly hydrophobic and feature outstanding transparency and excellent adhesion to metal surfaces.
Aluminium Stearate was found to coat the surface of pigment particles and helped prevent settling as well as reducing the amount of oil needed to wet the pigment.


The most frequently used colourants are synthetic; only a few natural substances are available.
For colourants, the applicable INCI names are in most cases the so-called Colour Index Numbers, the "CI Numbers".
The amount of Aluminium Stearate needed to coat pigments varied on a weight basis, but a solution of 2% by weight (weight of aluminum stearate/weight of oil) of Aluminium Stearate was more effective than 0.5% or 4% solutions in altering pigment surfaces.


According to the FDA, Aluminium Stearate is considered safe for general or specific, limited use in food.
Aluminium Stearate is not classifiable as a human carcinogen (cancer-causing agent).
They vary in terms of physical properties such as melting point, free fatty acids, and particularly the gelling properties.


Oils with a low viscosity are best thickened by aluminum di- and tri-stearate, whilst very viscous oils from stiffer gel when combined with aluminum mono- or di-stearates.
The soaps coat the surface of the pigments and by steric effects keep the particles from aggregating, which helps to keep the particles in suspension.


Aluminium stearate is good whiteness powder.
Aluminum Stearate is one of numerous organo-metallic compounds sold by American Elements for uses requiring non-aqueous solubility such as recent solar energy and water treatment applications.


Similar results can sometimes also be achieved with Nanoparticles and by thin film deposition.
Aluminium Stearate is insoluble in wate, oil, other solvents.
When strong acid is broken down into stearic acid and corresponding salt.


Aluminum stearate is an aluminum salt of stearic acid that functions as a thickening agent and helps stabilize products.
Types of aluminum stearates, generally classified as aluminum mono-, di-, and tri-stearate.
Aluminium stearate is soluble in alkalies, glycols, mineral and vegetable oils, chlorinated hydrocarbons, petroleum, benzene, turpentine oil, toluene and xylene.


Aluminum stearate is insoluble in water, ethanol and alcohols
Aluminium Stearate is insoluble in water, alcohol and ether; but when hot, it is readily soluble in benzene, acids and common solvents.
Aluminium tristearate is an aluminium salt.


Aluminium Stearate contains an octadecanoate.
Aluminum Stearate has the form of a white powder.
Aluminum Stearate is an aluminum salt of stearic acid.


Aluminum Stearate is the aluminum salt of the fatty acid, stearic acid.
Aluminium Stearate is insoluble in water, alcohol, and ether, but soluble in alkali, petroleum and turpentine oil.
Aluminium stearate is the aluminium salt of the fatty acid, stearic acid.


Aluminium Stearate is an organo-metallic compound formed from the reaction of aluminium and stearic acid.
Aluminium Stearate is a white, wax-like powder with a low melting point and is soluble in organic solvents.
Aluminium Stearate is soluble in glycol, alkali, BTX, chlorinated hydrocarbons.


If aluminium stearate is in high concentration, gelling can be seen upon cooling.
Aluminium Stearate is insoluble in water, alcohol and ether; but is readily soluble in benzene, acids and common solvents when hot.



USES and APPLICATIONS of ALUMINIUM STEARATE:
Aluminium Stearate forms a thixotropic gel on heating with mineral oils and solvents which is the main premise of its use and design.
Aluminium distearate is the most commonly used grade of aluminum stearate.
Aluminum Stearate is mainly used in the formulation of makeup products such as eyeliner, mascara, lipsticks, mascara, face powders, and foundations.


Aluminium Stearate is used increasing viscosity in greases (especially graphite grease)
Aluminium Stearate has been used as a Drier, thickener, Emulsifier, and matting agent in paints and varnishes although excess amounts produce soft, noncohesive films.


Aluminum stearate is also used to waterproof fabrics, ropes, Paper, Leather, Concrete, and Stucco.
Aluminium Stearate form waterproof coating along with wax for canvas fabric coating (eg., boots, military tents, wtc.)
When heated, Aluminium Stearate forms a gel with mineral oil, hence, acts as an anti-setting agent by forming a thixotropic gel in solvent-based paints.


This can be used to create a "cheaper" paint since a smaller amount of a costly pigment needs to be used.
A significant advantage of using stearates is that the oil and pigment do not separate greatly over long periods of time in the paint tube.
Aluminium Stearate is used as a gelling agent in many cosmetic formulations.


With increasing amounts of Aluminium Stearate the oil pigment mixture becomes viscous, and by using an appropriate amount of aluminum stearate the paint can gel at a lower pigment concentration.
This can be used to create a "cheaper" paint since a smaller amount of a costly pigment needs to be used.


Aluminium Stearate is also used in cement production for waterproofing and air entrainment, and in hot-melt paper coating compounds.
A significant advantage of using stearates is that the oil and pigment do not separate greatly over long periods of time in the paint tube.
The effects of metal soaps on pigments have been extensively studied.


Aluminum stearate was found to coat the surface of pigment particles and helped prevent settling as well as reducing the amount of oil needed to wet the pigment.
Manufacturers of artists' paints often use aluminum stearate in their formulations without listing it as a component on the product label.


Aluminium Stearate is used as an ingredient in photographic emulsions.
Occurrence in cosmetics: Oleogels, creams and ointments, powders
Aluminium Stearate exhibits relatively high solubility in hydrocarbon solvents (such as mineral spirits) when compared to other metallic stearates.


Aluminium Stearate is insoluble in water, alcohol and ether; but is readily soluble in benzene, acids and common solvents when hot.
Aluminum stearate has long storage life if stored in cool and dry location.
Manufacturers of artists' paints often use aluminum stearate in their formulations without listing it as a component on the product label.


Aluminium Stearate is used as heat stabilizer and lubricant for PVC plastics, antisettling and drying agent for paint industry, waterproofing agent for fabric, thickening agent for lubricating oil, etc.
Aluminium Stearate is used as a thickener in paints, inks and greases; a water repellent for leather and rope; and a lubricant in plastics and rope.


Aluminium Stearate is used as lubricant in polyamides and thermosetting of plastic, used as water repellent agent and hydrophobic agent in paint industry.
In recent years, hydrophobic Aluminium Stearate was tested as a low-solubility denitrification substrate for anaerobic bacteria and a source of aluminum for phosphate precipitation.


Aluminium Stearate is also used as thickening agent in production of varnishes and lacquers, and as an anti-caking agent in petroleum products.
Aluminum stearate is made via the precipitation process using high quality stearic acid and exhibits the following properties: Good gelling and thickening action, excellent water repellency, transparency and a synergistic effect with zinc stearate or calcium stearate.


Aluminium Stearate is mainly used as anti-setting agent, thickening agent
Aluminium Stearate is mainly used on plastics and petroleum oil
Aluminium Stearate is used as a lubricant, water repellent, Anti-caking agent, mould release agent and hydrocarbon gelling agent.


The amount of aluminum stearate needed to coat pigments varied on a weight basis, but a solution of 2% by weight (weight of aluminum stearate/weight of oil) of aluminum stearate was more effective than 0.5% or 4% solutions in altering pigment surfaces.
Other uses of Aluminium Stearate include paints and coatings.


Aluminium Stearate is used in foods as a buffer, firming agent and neutralising agent.
Aluminium Stearate is used in waterproofing fabrics, ropes; in paint and varnish driers; thickening lubricating oils; in cements; in light-sensitive photographic compositions.


Aluminium Stearate is a saline form of stearic acid used as a thickener and emulsifier, and to regulate the stability and suspension of a cosmetic formulation.
Aluminium Stearate is used for waterproofing fabrics and for thickening lubricating oils.


Aluminium Stearate is used Paint and varnish drier, greases, waterproofing agent, cement additive, lubricants, cutting compounds, flatting agent, and cosmetics.
Aluminium Stearate is involved in the preparation of polyamides and thermosetting plastics.


Aluminum stearate has potential for use in a flow-through container for denitrification of oxidized effluent from home sewage systems.
Aluminium Stearate acts as a gelling agent for alkyd paints, as a defoamer for oil drilling fluids and as a retarder for polysulfide dental impression materials.


Further, Aluminium Stearate is used in greases, lubricants, cutting compounds, cosmetics and pharmaceuticals.
Aluminium Stearate serves as a flatting agent, as a defoaming agent in beet sugar and yeast processing.
Relevant identified uses of Aluminium Stearate:
pharmaceuticals, defoaming agent in beet sugar and yeast processing.


In addition to this, Aluminium Stearate is used as a water-repellent soap for natural stone surfaces.
Aluminum stearate has been used to help suspend pigments in oil to prevent separation, to reduce the amount of oil needed to wet the pigment, and/or to increase the body of the paint by forming a gel with the oil thereby requiring less pigment.


Because of its unusually heavy bodying properties, Aluminium Stearate is used in the manufacture of paints, inks, greases, and waxes.
Aluminum Stearate surfactant is a powdered defoamer used primarily in water-based muds.
If you do use them they certainly do a good job of thickening the paint to a buttery consistency and prevent the separation of pigment and binder in the tube.


Aluminium Stearate is also used as a thickening agent in the production of varnishes and lacquers.
The recommendation against them is not that they don’t do the job; Aluminium Stearate is more about maximizing the purity of pigment color and strength which means minimizing any additive.


Aluminum Stearate are highly hydrophobic, and feature outstanding transparency and excellent adhesion to metal surfaces.
Because beeswax is heavier than Aluminum Stearate ۲% Beeswax is a lot less additive in the tube than 2% Aluminum Stearate.
Aluminium Stearate is used as a lubricant in the production of polyamides and thermosetting plastics.


Aluminum Stearate is commonly used as a paint and varnish dryer, waterproofing agent, defoaming agent, cement additive, in lubricants, cutting compounds, and in some food and pharmaceutical products.
Aluminium Stearate was also referred that the preheated mixture of metal soaps, along with the costabilizer, delayed the fast blackening of the polymer, but mainly showed a reduction.


Aluminium stearate is an important industrial chemical used in a wide range of applications including the manufacture of plastics, rubber, inks, paints, and adhesives.
Due to their water repellency, aluminum di- and tri-stearate are used as hydrophobic agents in the building industry.


Aluminium Stearate is also used in the production of cosmetics, pharmaceuticals, and food products.
Due to their water repellency Aluminium Stearate is used as hydrophobic agents in the building industry.
Aluminium stearate has a wide range of uses in laboratory experiments due to its ability to act as a stabilizing agent, emulsifier, and thickener.


The soaps coat the surface of the pigments and by steric effects keep the particles from aggregating, which helps to keep the particles in suspension.
Its unique properties make Aluminium Stearate an ideal choice for a variety of scientific research applications.
In the pharmaceutical industry, Aluminium Stearate is used as an anticaking agent; colorant; emulsion stabilizer; and viscosity increasing agent.


During the manufacturing of Aluminium Stearate, the particle size, shape, Bulk Density, and purity is closely controlled to ensure product quality & uniformity.
Aluminium Stearate is used as a waterproofing additive in cements and in light-sensitive photographic compositions.


With increasing amounts of aluminum stearate the oil pigment mixture becomes viscous, and by using an appropriate amount of aluminum stearate the paint can gel at a lower pigment concentration.
Aluminium Stearate exhibits relatively high solubility in hydrocarbon solvents (such as mineral spirits) when compared to other metallic Stearate.


-Paint Industry:
Aluminium stearate is used as a thickener in Varnishes/Lacquers, an anti-settling agent for pigmentation, as a pigment suspension, and an agent to improve water resistance and gloss.
Aluminium Stearate is useful as a water repellent agent, a hydrophobic agent, and a waterproof agent in the paint industry.
Aluminum stearate is a white powder soluble in oils and insoluble in water and alcohol.
Aluminium Stearate is used as a lubricant in the production of polyamides and thermosetting plastics, a thickening agent in production of varnishes and lacquers, a water repellent agent and hydrophobic agent, a paint drier and a defoaming agent.


-Applications of Aluminium Stearate:
*Paints and inks:
Alumium stearate as lubricants used on paints and inks
*Oil drilling:
Aluminium Stearate is used as defoamer.
Aluminium Stearate is used on oild drilling
*Styrene resin:
Aluminium Stearate is used as release agent.
*Plastics:
Aluminium stearate is used as PVC stabilizers and lubricants.
*Rubber:
Aluminium Stearate is used as a gloss agent.


-Cosmetics Industry:
Aluminium stearate is used as an emulsifier in cosmetics.
They are used for their lubricating properties.
The stearate salts also increase the thickness of the oil portion of cosmetics and personal care products.
Hence, finished cosmetics products are typically not transparent.


-Plastics Industry:
Metallic stearates, which have been used primarily as acid scavengers, lubricants and release agents by the plastics industry, are becoming increasingly important in melt processing.
In addition to optimizing production, the use of metallic stearates allows the processor to produce finished articles with smoother surfaces and lower friction.
Metallic stearates are mainly produced from organic raw materials.
Therefore, they tend to degrade to some degree when exposed to excessively high temperatures, resulting in discoloration.
Fanchem has developed a range of thermostable metallic stearates, which are highly resistant to discoloration when used in transparent or brightly colored thermoplastics even at high processing temperatures


-Paints, Varnishes and Lacquers:
Aluminium Stearate is adequate for improving pigments suspension, control of viscosity and gloss, water resistance and improving brushing and penetration.
Aluminium Stearate finds very wide application in paint industries for preparation of enamels and lacquers where it acts as thickening agent or suspending agent.
Aluminium Stearate reduces sagging and setting of pigment and works as varnish drier.
Aluminium Stearate is used as an important ingredient for water proofing in tarpaulin & textile industrie.


-Greases, Lubricating oils:
Aluminium Stearate gives excellent properties of transparency, stringiness and water repellency.
Aluminium Stearate acts as a high temperature resistant when added in lubricants.
Aluminium Stearate is used by ONGC for defoaming properties.


-Dry lubrication:
Aluminium Stearate is useful as a lubricant in metals processing, such as wire drawing, producing brighter products.
-Occurrence in other products:
In many industries as thickener, matting agent additive and for the hydrophobic treatment of absorbent materials such as paper, textiles and concrete


-Printing inks:
The high gelling properties of Aluminium Stearate are useful for thickening and suspension improving
-Plastics:
Aluminium Stearate is used in as a lubricant in the production of Polyamides and Thermosetting plastics.


-Rubber:
Aluminium Stearate is used as dusting powders to prevent sticking of unvulcanised rubber sheet.
-CONSTRUCTIONS :
Aluminium Stearate is recommended jointly with Calcium Stearate for improving the water resistance of concrete and cements.



IMPORTANT PROPERTIES OF ALUMINIUM STEARATE:
The important properties of our Aluminium Stearate, relevant to various applications are:
*Very Good gelling
*Thickening Action,
*Excellent Water Repellence
*Transparent Gel
*Synergistic effect with Zinc Stearate or Calcium Stearate.
*Low oversize particles.
*Purity.



HOW TO USE ALUMINIUM STEARATE:
Aluminum stearate dissolves in vegetable oils on heating and if a high enough concentration of the soap is used, gelling occurs on cooling.
In the usual practice of making paints, the aluminum stearate is ground with the pigment before the bulk of the oil is added.
To prepare a concentrated solution (10% w/v), add 100 grams of aluminum stearate (nearly fills a half liter measuring cup without compacting) to one liter of linseed oil.
Heat the oil to about 150° C. and gradually slowly adding the white powder to the hot oil with stirring.
Add one part of this solution to four parts of oil by weight of oil before adding to pigments and grinding.



SPECIAL FEATURES OF ALUMINIUM STEARATE:
Aluminium Stearate is very high gelling power.
Aluminium Stearate forms strong gel even at as low as 1.5-2.0% dosage.
Moisture depletes gelling power.



FUNCTIONS OF ALUMINIUM STEARATE IN COSMETIC PRODUCTS:
*ANTICAKING
Prevents powdered products from caking / sticking together
*COLORANT
Colours cosmetic products, skin, nails and / or hair
*EMULSION STABILISING
Supports emulsion formation and improves product stability
*VISCOSITY CONTROLLING
Increases or decreases the viscosity of cosmetic products



MECHANISM OF ACTION OF ALUMINIUM STEARATE:
Aluminium stearate acts as a stabilizing agent, emulsifier, and thickener in laboratory experiments.
Aluminium Stearate is a hydrophobic molecule, meaning it is not soluble in water.
When it is added to a solution, Aluminium Stearate forms a protective layer around the molecules, preventing them from reacting with each other.
This stabilizing effect is particularly useful in experiments involving highly reactive compounds.
Additionally, aluminium stearate acts as an emulsifier, allowing water-soluble and oil-soluble substances to mix together.
Finally, aluminium stearate acts as a thickener, increasing the viscosity of solutions.



SCIENTIFIC RESEARCH APPLICATION OF ALUMINIUM STEARATE:
Aluminium stearate has a wide range of applications in scientific research.
Aluminium Stearate is used as a stabilizing agent, emulsifier, and thickener in laboratory experiments.
Aluminium Stearate is also used to increase the viscosity of solutions, to control the rate of reaction, and to improve the solubility of compounds.
Aluminium stearate is also used in the production of cosmetics, pharmaceuticals, and food products.



FUNCTIONS OF ALUMINIUM STEARATE:
*Anti-caking agent: Ensures the fluidity of solid particles and limits their agglomeration in cosmetic products in powder or hard mass
*Cosmetic colorant: Colors cosmetics and/or imparts color to skin
*Emulsion Stabilizer: Aids the emulsification process and improves emulsion stability and shelf life
*Viscosity control agent: Increases or decreases the viscosity of cosmetics



REACTION OF ALUMINIUM STEARATE:
Dissolve stearic acid in a suitable solvent (e.g. ethanol)
Add aluminium chloride to the solution and stir until dissolved
Add the base to the solution and stir
Heat the mixture to reflux for several hours
Allow the mixture to cool and filter the resulting precipitate
Wash the precipitate with a suitable solvent (e.g. ethanol) and dry in a vacuum oven
The resulting product is Aluminium stearate



HOW TO USE OF ALUMINIUM STEARATE:
Aluminium Stearate dissolves in vegetable oils on heating and if a high enough concentration of the soap is used, gelling occurs on cooling.
In the usual practice of making paints, Aluminium Stearate is ground with the pigment before the bulk of the oil is added.
To prepare a concentrated solution (10%), add 200 grams of Aluminium Stearate (nearly fills a one liter measuring cup without compacting) to one liter of linseed oil.
Heat the oil to about 150C and gradually slowly adding the white powder to the hot oil with stirring.
Add one part of this solution to four parts of oil by weight of oil before adding to pigments and grinding.



MANUFACTURING PROCESS OF ALUMINIUM STEARATE:
Aluminium stearate is synthesised via the precipitation process using high quality stearic acid.
This is done by adding aluminium isopropoxide to stearic acid in anhydrous pyridine, inducing the precipitation of the pyridine complex.
Pyridine is then removed under vacuum to give the aluminium stearate.
Aluminium stearate is a fine, bulky, odourless and colourless powder forming a plastic mass when heated, having the properties both of organic and inorganic matter.
Aluminium Stearate embraces most of the characteristics of other metallic stearates and is regarded as the most important of these.
Several studies of the material have already appeared in past years.



SYNTHESIS METHOD OF ALUMINIUM STEARATE:
Aluminium stearate is synthesized by the reaction of aluminium and stearic acid.
The reaction is typically carried out at a temperature of 180-200°C and a pressure of 1.5-2.5 bar.
The reaction is usually carried out in an inert atmosphere, such as nitrogen or argon.
The reaction is complete when the aluminium has reacted with all of the stearic acid and the product is a white, wax-like powder.



BACKGROUND INFORMATION ON ALUMINIUM STEARATE USE IN COSMETICS:
Aluminium stearates are fatty acid salts (so-called metal soaps).
With oils and liquid paraffin they form gels which can serve as a cream basis.
Oleo gelling agents such as aluminium stearate are, therefore, used as thickening agents in liquid hydrophobic (water-repellent) phases.
They are a basic ingredient in oleogels on the basis of hydrocarbons, glycerides, polysiloxanes (silicones) or wax esters.
Moreover, they are used as swelling and thickening agents for cosmetic products and are applied, for instance, also for the production of astringent powders and creams (eg anti-perspirants).



WHAT DOES ALUMINIUM STEARATE DO IN A FORMULATION?
*Anticaking
*Cosmetic colorant
*Emulsion stabilising
*Viscosity controlling



SYNTHESIS METHOD DETAILS OF ALUMINIUM STEARATE:
Design of the Synthesis Pathway:
The synthesis pathway for Aluminium stearate involves the reaction between aluminium chloride and stearic acid in the presence of a base.
Starting Materials:
Aluminium chloride, Stearic acid, Base (e.g. sodium hydroxide)



SOLUBILITY OF ALUMINIUM STEARATE:
Aluminum stearate exhibits relatively high solubility in hydrocarbon solvents (such as mineral spirits) when compared to other metallic stearates.
Aluminium Stearate is insoluble in water, alcohol and ether; but is readily soluble in benzene, acids and common solvents when hot.



ALUMINIUM STEARATE VS. CALCIUM STEARATE
The chemical is insoluble in water and remain stable under various extreme as well as ordinary conditions.
Aluminium Stearate is and inorganic chemical with a molecular formula (C17H35COO)3Al and is appreciated for the features such as high efficiency, purity and chemical compositions.

Aluminium Stearate is a white coloured powder.
Aluminium Stearate is the aluminium salt of stearic acid.
Aluminium Stearate is insoluble in water, alcohol and ether.

However, Aluminium Stearate is soluble in glycol, alkali, BTX, chlorinated hydrocarbons.
Aluminium Stearate dissolves well in vegetable oils on heating and if high concentration is used, on cooling gelling is seen.
Aluminium Stearate is used as an emulsifier in cosmetics.

Aluminium Stearate is also used as lubricant in polyamides and in thermosetting of plastics.
Its use as a water repellent agent and hydrophobic agent makes Aluminium Stearate useful to be used as a waterproofing agent in paint industry.

Aluminium stearate is used as thickening agent in production of varnishes and lacquers.
Aluminium Stearate also finds use as an anticaking agent in petroleum products.
Due to high reactivity, calcium oxide is handled, stored and packaged ensuring minimal atmospheric contact at our premises.

Calcium Stearate is an insoluble salt of calcium, stearic acid and palmatic acid.
In hard water, when soap of calcium ions is mixed, the scum that is formed is calcium stearate.
Calcium stearate is non-toxic and has many applications as stabilizer and lubricant.

Besides water, it is insoluble in water, ether, chloroform, acetone, cold alcohol as well.
However, it is slightly soluble when dissolved in hot alcohol, hot vegetable and mineral oil.
It shows good solublity in hot pyridine.

The use of calcium stearate is seen widely as a stabilizer for PVC resins and lubricant for plastic moulding powders or tablets.
Its use is recommended also in emulsions, cements, pencils, construction chemicals, paint flattening agent, resin coated sands and foundry chemicals, decaking agent in food items like onions and cosmetics.

Use of calcium stearate is seen as a lubricating agent in paper and paperboard coating compositions, iron wire drawing and leather cloth manufacturing as well.
Its use has been extended as a neutralizer, colour stabilizer, reducer of fiber breakage and de-agglomerator in PP and HDPE applications.
Calcium stearate is also known as octadecanoic acid calcium salt, stearic acid calcium salt.



PHYSICAL and CHEMICAL PROPERTIES of ALUMINIUM STEARATE:
Molecular Weight: 877.39
Molecular Formula: 3(C18H35O2)?Al
Boiling Point: 359.4ºC at 760 mmHg
Melting Point: 103ºC
Flash Point: 162.4ºC
Purity: N/A
Density: 1.01
Appearance: solid
Storage: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Color&Appearance: White Fine Powder
Al content,%: 3.1-3.2
Moisture,%: 5max
Through 180 mesh,%: 99.0min
Melting Point: 120-130
Free fatty acid,%: <8.0
Ash,%: 5.8-6.0

Molecular Weight: 877.4
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 45
Exact Mass: 876.7726545
Monoisotopic Mass: 876.7726545
Topological Polar Surface Area: 120 Ų
Heavy Atom Count: 61
Formal Charge: 0
Complexity: 196
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 4
Compound Is Canonicalized: Yes
Compound Formula: C54H105AlO6
Molecular Weight: 877.38
Appearance: White Powder
Melting Point: 103-155 °C
Boiling Point: 2467°C @ 101.325 hPa
Density: 1.01 g/cm3
Solubility in H2O: N/A
Exact Mass: 876.772655
Monoisotopic Mass: 876.772655

Linear Formula: Al(C18H35O2)3
MDL Number: MFCD00036389
EC No.: 211-279-5
Pubchem CID: 12496
IUPAC Name: aluminum; octadecanoate
SMILES: [Al+3].[O-]C(=O)CCCCCCCCCCCCCCCCC.[O-]C(=O)CCCCCCCCC[O-]CCCCCCCC.C(=O)CCCCCCCCCCCCCCCCC
InchI Identifier: InChI=1S/3C18H36O2.
InchI Key: CEGOLXSVJUTHNZ-UHFFFAOYSA-K
Physical state: solid
Color: No data available
Odor: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility No data available
Partition coefficient: n-octanol/water: No data available

Vapor pressure: No data available
Density: 1,350 g/cm3
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Molecular Weight: 877.39
Molecular Formula: 3(C18H35O2)?Al
Boiling Point: 359.4ºC at 760 mmHg
Melting Point: 103ºC
Flash Point: 162.4ºC
Purity: N/A
Density: 1.01
Appearance: solid
Storage: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Hazard Codes: Xi
HS Code 2915709000
Log P: 18.76620
PSA: 78.9
Risk Statements: R36/37/38
RTECS: BD0707000
Safety Statements: S22-S24/25
Stability: Stable.



FIRST AID MEASURES of ALUMINIUM STEARATE:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ALUMINIUM STEARATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of ALUMINIUM STEARATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Special hazards arising from the substance or mixture
Nature of decomposition products not known.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of ALUMINIUM STEARATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Wash and dry hands.
*Body Protection:
Choose body protection in relation to its type.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ALUMINIUM STEARATE:
-Precautions for safe handling:
*Hygiene measures:
General industrial hygiene practice.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage class:
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of ALUMINIUM STEARATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
637-12-7
AI3-01515
AKOS015901563
ALUGEL 30DF
ALUGEL 34TH
Alugel 34TN
Aluminium stearate
ALUMINIUM STEARATE [EP MONOGRAPH]
ALUMINIUM STEARATE [WHO-DD]
aluminium trioctadecanoate
aluminium tristearate
Aluminium tristearate, pure
Aluminum (III) stearate
Aluminum octadecanoate
Aluminum stearate
Aluminum stearate (1:3)
ALUMINUM STEARATE [II]
ALUMINUM STEARATE [MI]
ALUMINUM STEARATE [VANDF]
Aluminum stearate, tribasic
aluminum trioctadecanoate
ALUMINUM TRISTEARATE
ALUMINUM TRISTEARATE [HSDB]
ALUMINUM TRISTEARATE [INCI]
Aluminum(III) stearate
Aluminum, dihydroxy(octadecanoato-O)-
octadecanoate
ALUMINUMTRISTEARATE
C18-H36-O2.1/3Al
C18H36O2.1/3Al
CHEBI:37867
DB11290
Dihydroxy(octanoato-O)aluminum
DTXSID0027278
EINECS 211-279-5
FT-0622241
HSDB 5733
LS-146665
Metasap XX
Monoaluminum stearate
Octadecanoic acid aluminum salt (3:1)
Octadecanoic acid, aluminium salt
Octadecanoic acid, aluminum salt
Octadecanoic acid, aluminum salt (3:1)
Q447821
Rashayan Aluminium Stearate
Rofob 3
SA 1500
Stearic acid aluminum salt
Stearic acid, aluminum salt
Tribasic aluminum stearate
Tristearic acid aluminum
U6XF9NP8HM
UNII-U6XF9NP8HM
alugel34tn
aluminum(iii)stearate
aluminumstearate(1:3)
metasapxx
monoaluminumstearate
Octadecanoicacid,aluminiumsalt
octadecanoicacid,aluminumsalt
rofob3
Stearic acid aluminium salt
Trioctadecanoic acid aluminum salt
Trisstearic acid aluminum salt
Tristearic acid aluminum
Tristearic acid aluminum salt
Aluminum octadecanoa
octadecanoicacid,aluminumsalt
rofob3
ALUMINIUM STEARATE
ALUMINUM MONOSTEARATE
ALUMINUM TRISTEARATE
sa1500
rofob3
metasapxx
alugel34tn
TechnicalGrade
(C17H35COO)2AIOH
ALUMINUM STEARATE
aluminum monostearate
Aluminum stearate
Aluminium stearate
637-12-7
aluminium tristearate
Aluminum octadecanoate
ALUMINUM TRISTEARATE
Aluminum(III) stearate
Alugel 34TN
Octadecanoic acid, aluminum salt
U6XF9NP8HM
Octadecanoic acid, aluminum salt (3:1)
Metasap XX
Tribasic aluminum stearate
Rofob 3
Monoaluminum stearate
Aluminum (III) stearate
Aluminum stearate (1:3)
Aluminum stearate, tribasic
HSDB 5733
EINECS 211-279-5
UNII-U6XF9NP8HM
Aluminium tristearate, pure
SA 1500
Dihydroxy(octanoato-O)aluminum
AI3-01515
aluminum;octadecanoate
Aluminum, dihydroxy(octadecanoato-O)-
aluminum trioctadecanoate
Tristearic acid aluminum
aluminium trioctadecanoate
ALUMINUMTRISTEARATE
ALUGEL 30DF
ALUGEL 34TH
Rashayan Aluminium Stearate
ALUMINUM STEARATE [II]
ALUMINUM STEARATE [MI]
DTXSID0027278
CHEBI:37867
ALUMINUM STEARATE [VANDF]
ALUMINUM TRISTEARATE [HSDB]
ALUMINUM TRISTEARATE [INCI]
ALUMINIUM STEARATE [WHO-DD]
MFCD00036389
AKOS015901563
DB11290
ALUMINIUM STEARATE [EP MONOGRAPH]
FT-0622241
Q447821
Aluminum octadecanoate
Aluminium trioctadecanoate
Octadecanoic acid, aluminum salt
Aluminum(III) stearate
aluminium tristearate
aluminum tristearate
Tribasic aluminum stearate
stearic acid, aluminum salt
Monoaluminum stearate
C18-H37-Al-O4
aluminium dihydroxy(octadecanato-O-)
aluminium dihydroxy(stearato)-
aluminum dihydroxy stearate
dihydroxyaluminium stearate
aluminium monostearate
dibasic aluminium stearate
aluminium stearate H.G.
Monoaluminum Stearate
Aluminum Distearate
Aluminum Tristearate
Stearic Acid aluminum salt
Octadecanoic Acid, Aluminum Salt
Aluminum Monostearate
alugel34tn
aluminum(iii)stearate
aluminumstearate(1:3)
metasapxx
monoaluminumstearate
Octadecanoicacid,aluminiumsalt
octadecanoicacid,aluminumsalt
rofob3
Aluminium Stearate
Aluminium octadecanoate
Aluminium tristearate
Aluminium salt
Aluminium tristearate
aluminium (tri) stearate
Aluminium stearate tech
Aluminium stearate white powder
aluminium octadecanoate
octadecanoate, Aluminium salt
aluminum tristearate
ammonium stearate
calcium stearate
magnesium stearate
octadecanoic acid
sodium stearate
stearic acid
zinc stearate



ALUMINIUM STEARATE
Hydrated alumina; Alumina hydrate; Alumina trihydrate; ATH; Aluminum hydrate; Aluminum trihydrate; Alhydrogel; Superfos; Amphogel; Aluminum (III) hydroxide; Amorphous alumina; Trihydrated Alumina; Trihydroxyaluminum CAS NO:21645-51-2
ALUMINIUM TRIHYDRATE
Reach AZP 902; Reach AZP 908 Superfine GL; Reach AZP 908SUF; Reheis 36 GPC; Reheis AZG; Rezal 36 GP SUF; Rezal 36G; Rezal 36GC; Aluminum zirconium tetrachlorohydrex gly; Aluminum zirconium tetrachlorohydrex glycine complex; UNII-8O386558JE; Westchlor ZR 41; Wickenol CPS 370; Z 535; Z 756; Zirconal 50 CAS NO:134910-86-4
ALUMINIUM TRIHYDRATE
Aluminum Trihydroxide, also known as aluminum trihydroxide, aluminum trihydrate, aluminum hydrate, hydrated alumina, and hydrated aluminum oxide, is a white to whitish-yellow water-insoluble powder with a specific gravity of 2.42.
Aluminum Trihydroxide is an electrical insulator, which means it doesn’t conduct electricity, and it also has relatively high thermal conductivity.
The chemical formula for Aluminum Trihydroxide is Al(OH)₃.

CAS Number: 21645-51-2
Molecular Formula: AlH3O3
EINECS Number: 244-492-7

Aluminum Trihydroxide, in its crystalline form, corundum, its hardness makes it suitable as an abrasive.
The high melting point of Aluminum Trihydroxide makes it a good refractory material for lining high-temperature appliances like kilns, furnaces, incinerators, reactors of various sorts, and crucibles.
Aluminum Trihydroxide is used as a baseforpigments, as a water repellent in textile coatings, and as an antacid in medicine.

Aluminum Trihydroxide is soluble in hydrochloric or sulfuric acids or in sodiumhydroxide.
Aluminum Trihydroxide is derived from the mineral bauxite and is a common compound in nature.

Aluminium trihydroxide, also known as alumina trihydrate is the most economic and widely used flame retardant and smoke suppressant in the plastics industry.
Aluminum hydroxide together are the major components of the aluminium ore bauxite.

Aluminum trihydroxide also forms a gelatinous precipitate in water.
Aluminum trihydroxide is to be added to casting resins / surface casting this will create a more heat resistant object and increase the fire retardant properties of the cast material.
Aluminum Trihydroxide needs to be incorporated in high loading which can impair the mechanical and electrical properties of the polymer.

Aluminum Trihydroxide is an inorganic salt used as an antacid.
Aluminum Trihydroxide is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions.
Aluminum Trihydroxide used commercially is manufactured by the Bayer process which involves dissolving bauxite in sodium hydroxide at temperatures up to 270 °C (518 °F).

Aluminum trihydroxide, also known as Aluminum Trihydroxide or alumina trihydrate, is a white, odorless, and insoluble powder with the chemical formula Al(OH)3.
Aluminum trihydroxide is often associated with its role as a non-halogen flame retardant and smoke suppressant, and for good reason, as Aluminum Trihydroxide is the largest selling fire retardant additive in the world.
This Aluminum Trihydroxide can be converted to aluminium oxide or alumina by calcination.

Of the common fillers used in Plastics, Rubber, FRP, SMC, DMC moulding and other polymers only Aluminum Trihydroxide has flame retarding and smoke suppressing properties as well as being an economical resin extender.
Alumina Chemical & Castables is the leading developer & Processor of Aluminum Trihydroxide.
Aluminum Trihydroxide is the hydroxide salt form of aluminum designed for oral ingestion.

Aluminum Trihydroxide is sometimes used to treat, control, or manage high levels of phosphate in the body.
Aluminum Trihydroxide is also used with a low phosphate diet to prevent the formation of phosphate urinary stones. Aluminum Trihydroxide is also found in personal care products and industrial applications.

Aluminum Trihydroxide is used as an antacid and included as an adjuvant in some vaccines.
Aluminum Trihydroxide acts as a flame retardant and smoke suppressor because of its thermodynamic properties.
Aluminum Trihydroxide is endothermic dehydration cools the plastic & Rubber parts and dilute with water vapour those combustible gases that do escape.

Aluminum Trihydroxide is an inorganic white fine crystalline, non-hygroscopic powder.
Aluminum is the most abundant metal in the earth's crust and is always found combined with other elements such as oxygen, silicon, and fluorine. (L739, L740, L756)
Aluminum Trihydroxide is used in polyester resins however with increased attention being given to smoke & toxic fume emissions, Aluminum Trihydroxide has found large volume application in vinyl as a low smoke, non toxic replacement for antimony and in polyurethane, latex, neoprene foam system, Rubber, wire & Cable insulation, vinyl walls & flooring coverings and epoxies.

Aluminium hydroxide is the most stable form of aluminium.
Aluminum Trihydroxide is used for the relief of heartburn, sour stomach, acid indigestion, stomach ulcers, peptic ulcer pain, and to promote the healing of peptic ulcers.
Aluminum trihydroxide, Al(OH)3, is found in nature as the mineral gibbsite (also known as hydrargillite) and its three much rarer polymorphs: bayerite, doyleite, and nordstrandite.

Aluminum Trihydroxide is solubility in water and organic solvents is very low.
Aluminum Trihydroxide is the largest flame retardant (FR) used in diverse end applications.
The remaining metal oxide residue has a high internal surface where sooty particles, respectively polycyclic aromatic hydrocarbons, are absorbed, making Aluminum Trihydroxide also a smoke suppressant.

Aluminum Trihydroxide widely use in Paper Industries as a whitening agent in place of titanium dioxide.
Aluminum Trihydroxide is also use in Paints Industries.
Aluminum Trihydroxide also finds use as a fire retardant filler for polymer applications.

Aluminum Trihydroxide is selected for these applications because it is colorless (like most polymers), inexpensive, and has good fire retardant properties.
Aluminum Trihydroxide decomposes at about 180 °C (356 °F), absorbing a considerable amount of heat in the process and giving off water vapour.
Aluminum Trihydroxide can replace upto 25% of the Titanium dioxide pigment & therefore is an economical extender reducing production cost.

In plasticised PVC fine precipitated Aluminum Trihydroxide is used as FR and smoke suppressant.
Aluminum Trihydroxide is very effective as a smoke suppressant in a wide range of polymers, most especially in polyesters, acrylics, ethylene vinyl acetate, epoxies, polyvinyl chloride (PVC) and rubber.
Aluminum Trihydroxide disassociates enough in many glaze types to be useful as a source of Al2O3 to the melt (the finer the particle size the better).

Aluminum Trihydroxide stays in suspension better in glaze slurries and has better adhesive qualities also, using hydrated alumina in glazes and glasses can promote a fining operation by coalescing finely dispersed gas bubbles.
Coarser Aluminum Trihydroxide types produced by grinding are used in large volume in thermoset applications.
Cast resins and glass fibre reinforced products like BMC (Bulk Moulding Compounds) and SMC (Sheet Moulding Compounds) are processed in electrical and electronic appliances as well as in construction applications.

Aluminum Trihydroxide added to a glaze can also enhance the color of Cr-Al pinks.
Larger additions of fine material can impart matteness if the glaze is able to take it into solution (sourcing alumina from kaolin, feldspar and frits is obviously more practical since these decompose readily in glaze melts).
Aluminum Trihydroxide is used as an antacid in humans and animals (mainly cats and dogs).

The oxide layer acts as a barrier protecting the polymer against further decomposition.
Aluminum Trihydroxide is commercially available in grain sizes ranging from 0.5 – 80 µm in median particle size (D50). In Halogen Free Flame Retardant (HFFR) wire and cables (W&C), one of the largest markets for Aluminum Trihydroxide, fine precipitated Aluminum Trihydroxide is used in sheAluminum Trihydroxideing and insulation.
The working principle is based on the thermal decomposition of Aluminum Trihydroxideinto aluminium oxide and water.

Aluminum Trihydroxide is preferred over other alternatives such as sodium bicarbonate because Al(OH)3, being insoluble, does not increase the pH of stomach above 7 and hence, does not trigger secretion of excess acid by the stomach.
Aluminum Trihydroxide reacts with excess acid in the stomach, reducing the acidity of the stomach content, which may relieve the symptoms of ulcers, heartburn or dyspepsia.
Aluminum Trihydroxide can cause constipation, because the aluminium ions inhibit the contractions of smooth muscle cells in the gastrointestinal tract, slowing peristalsis and lengthening the time needed for stool to pass through the colon.

Aluminum Trihydroxide is formulated to minimize such effects through the inclusion of equal concentrations of magnesium hydroxide or magnesium carbonate, which have counterbalancing laxative effects.
Aluminium trihydrate (Aluminum Trihydroxide) is initially derived from bauxite ore, before being refined into a fine white powder.

Aluminum Trihydroxide is initially derived from bauxite ore, before being refined into a fine white powder.
The waste solid, bauxite tailings, is removed and Aluminum Trihydroxide is precipitated from the remaining solution of sodium aluminate.
Aluminum Trihydroxide is also used to control hyperphosphatemia (elevated phosphate, or phosphorus, levels in the blood) in people and animals suffering from kidney failure.

Aluminum Trihydroxide increases in pH may inhibit the action of pepsin an increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects.
Aluminium trihydroxide is employed in acrylic rubbers and moulding, thermosetting resins, thermoplastic cable sheAluminum Trihydroxideing, PVC flooring etc.
Aluminum Trihydroxide is amphoteric,it has both basic and acidic properties.

Aluminum Trihydroxide normally, the kidneys filter excess phosphate out from the blood, but kidney failure can cause phosphate to accumulate.
Aluminum Trihydroxide salt, when ingested, binds to phosphate in the intestines and reduce the amount of phosphorus that can be absorbed.
Closely related are Aluminum trihydroxide, AlO(OH), and aluminium oxide or alumina (Al2O3), the latter of which is also amphoteric.

Molar mass: 78.00 g/mol
Appearance: White amorphous powder
Density: 2.42 g/cm3, solid
Melting point: 300 °C (572 °F; 573 K)
Solubility in water: 0.0001 g/100 mL
Solubility product (Ksp): 3×10−34
Acidity (pKa): >7
Isoelectric point: 7.7
Boiling point: 2980℃[at 101 325 Pa]
vapor pressure: storage temp.: Store at +5°C to +30°C.
solubility: 0.0015g/l
Color: White
Specific Gravity: 2.42
PH Range: >7
PH: 8-9 (100g/l, H2O, 20℃)(slurry)
Exposure limits ACGIH: TWA 1 mg/m3

Vaccine formulations containing Aluminum Trihydroxide stimulate the immune system by inducing the release of uric acid, an immunological danger signal.
Aluminum Trihydroxide strongly attracts certain types of monocytes which differentiate into dendritic cells.
Aluminum Trihydroxide is a feedstock for the manufacture of other aluminium compounds: calcined aluminas, aluminium sulfate, polyaluminium chloride, aluminium chloride, zeolites, sodium aluminate, activated alumina, and aluminium nitrate.

Freshly precipitated Aluminum Trihydroxide forms gels, which are the basis for the application of aluminium salts as flocculants in water purification.
Aluminum Trihydroxide gel crystallizes with time.
Precipitated Aluminum Trihydroxide is included as an adjuvant in some vaccines (e.g. anthrax vaccine).

One of the well-known brands of Aluminum Trihydroxide adjuvant is Alhydrogel, made by Brenntag Biosector.
Aluminum Trihydroxide is sometimes called "alum", a term generally reserved for one of several sulfates.

Aluminum Trihydroxide appears to contribute to induction of a good Th2 response, so is useful for immunizing against pAluminum Trihydroxideogens that are blocked by antibodies however, it has little capacity to stimulate cellular (Th1) immune responses, important for protection against many pAluminum Trihydroxideogens, nor is it useful when the antigen is peptide-based.
Aluminum Trihydroxide gels can be dehydrated (e.g. using water-miscible non-aqueous solvents like ethanol) to form an amorphous aluminium hydroxide powder, which is readily soluble in acids.

Heating converts it to activated Aluminum Trihydroxide, which are used as desiccants, adsorbent in gas purification, and catalyst supports.
The residue or bauxite tailings, which is mostly iron oxide, is highly caustic due to residual Aluminum Trihydroxide.
Aluminum Trihydroxide was historically stored in lagoons; this led to the Ajka alumina plant accident in 2010 in Hungary, where a dam bursting led to the drowning of nine people.

Aluminum Trihydroxide, white solid, is a typical amphoteric hydroxide that is insoluble in water but soluble in acid or alkali.
Aluminum Trihydroxide is a widely used chemical product, and it is mainly used as plastic and polymer fillers, blanket flame retardant and binder, epoxy resin filler, toothpaste fillers, glass ingredients as well as paper color fillers and coatings.

The purified Aluminum Trihydroxide has form of bulky powder of white color or granules with density nearly 2.42 g per mL. Aluminum Trihydroxide won’t dissolve in water, but will dissolve only in bases and acids.
Aluminum Trihydroxide to act as an amphoteric substance in water.
Aluminum Trihydroxide will act as an acid. And if a strong acid is present, it will act as a strong base.

Aluminum Trihydroxide should be handled with caution because its exposure can cause irritation however, only minor and residual injuries will be present.
As for flammability, Aluminum Trihydroxide is not flammable and will not burn.
Aluminum Trihydroxide is not reactive, therefore, it is stable in both fire and water conditions.

Aluminum Trihydroxide is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 000 to < 10 000 000 tonnes per annum.
Aluminum Trihydroxide used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Aluminum Trihydroxide can be also used to product sulfuric acid Aluminum, alum, aluminum fluoride and sodium aluminate, and to synthesize molecular sieve.

Aluminum Trihydroxide gel and drying gel of Aluminum Trihydroxide can be used in medicine as antacids to neutralize gastric acid and protect ulcer surface for the treatment of gastric and duodenal ulcer disease and hyperacidity.
Aluminum Trihydroxide can be transformed into alumina after heated in the air for dehydration, which is important for alumina production.

Production Method Of Aluminum Trihydroxide:
97% of the bauxite ores produced worldwide each year are treated with Bayer method to obtain Aluminum Trihydroxide.
Aluminum trihydroxide has a density of 2.42 g/cm3, a melting point of 300°C, and a Mohs hardness of 2.5-3.5.
Aluminum Trihydroxide is insoluble in water and organic solvents, but it can dissolve in strong acids and bases.

Aluminum Trihydroxide is a weak base and can act as a buffer in solution.
Aluminum trihydroxide is typically produced by the Bayer process, which involves extracting aluminum from bauxite ore through a series of chemical reactions.
The resulting Aluminum Trihydroxide is then calcined (heated) to remove water and produce alumina, a precursor to aluminum metal.

Sodium aluminate solution and the aluminum sulfate solution are neutralized to pH 6.5 to produce Aluminum Trihydroxide precipitate.
The obtained precipitate is washed with water, filtered and dried at 70-80℃ for 12 hours, and then crushed to prepare the Aluminum Trihydroxide product.
A12O3+2NaOH→2NaAO2+H2O
Al2O3+3H2SO4→A12(SO4)3+3H2O
6NaAIO2+A12(SO4)3+12H2O→8Al(OH)3↓+3Na2SO4

Recycled aluminum chloride is dissolved in water, decolorized with activated carbon and filtered to remove impurities, and then react with sodium carbonate to produce raw Aluminum Trihydroxide.
The raw products are filtered, washed and dried to obtain the final Aluminum Trihydroxide products.
2A1C13+3Na2CO3+3H2O→2AI(OH)3↓+6NaCl+3CO2↑

Metabolism Of Aluminum Trihydroxide:
Aluminum Trihydroxide or oxide is slowly solubilised in the stomach and reacts with hydrochloric acid to form aluminium chloride and water.
Aluminum trihydroxide, dihydroxyaluminium sodium carbonate and aluminium carbonate form carbon dioxide, and aluminium phosphate forms phosphoric acid.

Aluminum trihydroxide formed is absorbed and is rapidly excreted by the kidneys in patients with normal renal function.
Aluminum trihydroxide antacids also combine with dietary phosphate in the intestine forming insoluble, nonabsorbable aluminium phosphate which is excreted in the faeces.

Uses
Aluminum trihydroxide is used as an antacid to treat heartburn, acid indigestion, and other gastrointestinal problems.
Aluminum trihydroxide is a commonly used flame retardant in plastics, rubbers, coatings, and other materials.
When exposed to heat, Aluminum trihydroxide decomposes to release water vapor and carbon dioxide, which help to cool and dilute the flame, slowing down the combustion process and reducing the spread of fire.

Aluminum trihydroxide works by neutralizing excess stomach acid, thereby reducing symptoms.
Aluminum trihydroxide is used as an adjuvant in some vaccines to enhance the immune response and improve vaccine effectiveness.
Aluminum trihydroxide works by stimulating the immune system to produce a stronger response to the vaccine antigen.

Aluminum trihydroxide is used in water treatment to remove impurities and improve water quality.
Aluminum trihydroxide is used as a filler in ceramics and glass to improve their strength and other properties.
Aluminum trihydroxide is used in the production of construction materials such as insulation, roofing, and wallboard as a flame retardant and filler.

Aluminum trihydroxide can be used as a topical treatment for skin conditions such as diaper rash and poison ivy.
Aluminum trihydroxide is used in a wide range of industries, including pharmaceuticals, water treatment, and flame retardants.

Aluminum trihydroxide is used as an antacid to neutralize excess stomach acid and as an adjuvant in vaccines to stimulate an immune response.
Aluminum trihydroxide is used in the production of aluminum chemicals, such as aluminum sulfate and polyaluminum chloride, which are used in water treatment, paper production, and other applications.
Aluminum trihydroxide can be used as a coagulant to help remove suspended solids, turbidity, and color from water.

Aluminum trihydroxide is used to prevent or slow down the spread of fire in plastics, fabrics, and building materials.
Aluminum Trihydroxide is an inorganic compound used to make a product less transparent.
Aluminum trihydroxide used for preparing waterproof fabrics, inks, glass, paper fillers, mordant, purifying agent, various aluminum salts, etc.

Aluminum trihydroxide widely used for plastics, rubber, resin, paint, paint and so on.
Aluminum trihydroxide used for supporting catalyst and separating the vapor liquid.
Aluminum trihydroxide is also used by formulators as a humectant, and to soften, smooth, and protect the skin it helps control product viscosity often found in facial masks and make-up preparations.

Aluminum trihydroxide used in the industries of petroleum, chemical, fertilizer, natural gas and environmental protection for increasing the gas or liquid distribution points and protecting the low-strength catalyst.
Aluminum trihydroxide used as mordants and analysis reagents.

Aluminum trihydroxide used for the gravimetric determination of potassium content
Aluminum trihydroxide used as adsorbents, emulsifiers, ion exchangers, chromatographic analytes and mordants.
Aluminum Trihydroxide gel can be used for the treatment of duodenal ulcer, gastric ulcer and hyperacidity embolism.

In addition, also used in waterproof fabrics, paper fillers, mordant and purifying agent.
Aluminum trihydroxide used as the thickener for ink and the raw materials for manufacturing aluminum salt, enamel, ceramics, glassware and lubricant also used for the preparation of various catalyst carrier.
Just to illustrate the broadness of the uses, we can say that Aluminum Trihydroxide is used as mordant in dyes, purifier for water, ingredient for cosmetics, and even in as an element for processes in photography.

Aluminum trihydroxide is also applications of minor character in ceramics and construction but the most important field where Aluminum Trihydroxide is applied is medicine.
Aluminum trihydroxide used for printing inks, painting pigments, crayons and rubber packing.
Aluminum trihydroxide uses in waterproof fabric, ink, glassware, paper packing, mordant, purifying agent and also used in aluminum salt, lubricant manufacture.

Aluminum trihydroxide is used in the following products: cosmetics and personal care products, coating products, inks and toners, fillers, putties, plasters, modelling clay, pharmaceuticals, adhesives and sealants, washing & cleaning products, lubricants and greases and polishes and waxes.
Release to the environment of Aluminum trihydroxide can occur from industrial use: formulation of mixtures and formulation in materials.

Aluminum trihydroxide is also very useful because cement with Aluminum Trihydroxide addition dries rapidly if it is being exposed to heat.
Aluminum trihydroxide is use as an antacid and vaccine adjuvant, aluminum trihydroxide has also been used as a phosphate binder in patients with kidney disease and as a topical treatment for skin conditions such as diaper rash and poison ivy.

Aluminum trihydroxide is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
On the stage of production of concrete Aluminum Trihydroxide is added to cement.
Ceramics and glass of both industrial and home application is manufactured using Aluminum Trihydroxide.

The most useful feature of Aluminum Trihydroxide when it is added to glass consists in the fact that it makes glass heat-resistant.
Aluminum trihydroxide is possible because, as have been already mentioned, Aluminum Trihydroxide is not flammable and has high melting point.
Aluminum Trihydroxide combined with polymers appears to be a very good fire retardant.

Aluminum Trihydroxide is most frequently used for the production of lipsticks, make-ups, and other products for skin care.
Aluminum Trihydroxide is used there because it is totally stable and non toxic for people.
Aluminum Trihydroxide manufacturers of cosmetics also use Aluminum Trihydroxide to produce cleansers for skin, suntan products, body lotions, and moisturizers.

Aluminum trihydroxide used for the preparation of refractory, glass and pottery, as well as precipitation pigment and waterproof fabric also used for the manufacture of aluminum salts.
Personal care products, for example, shampoos, toothpastes, deodorants and many others, also involve using of Aluminum Trihydroxide.
Aluminum Trihydroxide is able to neutralize acids, it serves as a natural antacid.
Aluminum Trihydroxide also has a very useful property as it stimulates the immune system of human.

Aluminum trihydroxide, various vaccines, including those that are used to treat hepatitis B, hepatitis A, and tetanus, are prepared using Aluminum Trihydroxide.
Aluminum trihydroxide can be also used for the treatment of kidney patients who have high level of phosphates in blood due to renal failure.
Aluminum trihydroxide useful feature exists due to the ability of Aluminum Trihydroxide to bind with phosphates.

Aluminum Trihydroxide, phosphates are flushed out of the human body easily.
Aluminum Trihydroxide has many advantages including large-scale production, adequate raw materials, high product purity and good solubility in acid.
Aluminum Trihydroxide can transform into alumina, which has high thermal chemical stability, thermal strength, creep resistance and dielectric properties and low thermal expansion coefficient. Alumina is an important material for the synthesis of ceramics.

In the process of ceramic synthesis, we can control the phase formation of the composite by Aluminum Trihydroxide activation and crystallization process controlling.
Aluminum Trihydroxide can be used as an important raw material for the preparation of aluminum salts, such as barium aluminate, aluminum sulfate and so on.
Aluminum Trihydroxide powder is commonly regarded as an ideal flame retardant filler for plastics, unsaturated polyester, rubber and other organic polymers because of its filling, flame retardant and smoke-eliminating functions and non-toxic property.

Flame retardant mechanism of Aluminum Trihydroxide is as follows: when the temperature exceeds 200 ℃, the Aluminum Trihydroxide begin to perform endothermic decomposition and release three crystal water, and its decomposition rate reaches the largest at 250℃.
Aluminum trihydroxide thereby inhibiting the polymer temperature rise, reducing its decomposition rate and only producing water vapor, not generating toxic and harmful gases.

Aluminum Trihydroxide exists in water mainly in form of Al(OH)4-, which can precipitate toxic heavy metals in sewage by coprecipitation method to achieve the effect of water purification after further filter.
Sol-gel method is commonly used for the preparation of ultra-fine Aluminum Trihydroxide.
The most common sol-gel method for the preparation of Aluminum Trihydroxide is the hydrolysis of aluminum salts and alkoxides in water, the mechanism of which is divided into two steps: 1)-OR group is hydrolyzed to produce-OH; 2) Al3+ reacts with –OH to separate Aluminum Trihydroxide precipitation out.

Carbon fractionation is a method that is performed as follows: Introduce CO2 gas into sodium metaaluminate solution to make Aluminum Trihydroxide precipitate down and control the size and morphology of products by adjusting the pH value and CO2 concentration.
Aluminum Trihydroxide, microemulsion is typically composed of surfactants, cosurfactants, solvents and water (or aqueous solution).
Aluminum Trihydroxide, microemulsion has many excellent properties such as ultra-low interfacial tension and high solubilization capacity.

The preparation of nano-materials by microemulsion technology can precisely control the crystal growth process of nano-materials, and the micro-emulsion ball can encapsulate the crystal particles to effectively prevent the agglomeration of nano-particles.
The Aluminum Trihydroxide as adjuvant can also improve the immunogenicity of the vaccine, the action mechanism of which is as follows: Aluminum Trihydroxide adsorbs antigen on its surface to allow the antigen slow release so that it can play the role of extending efficacy.
Aluminum Trihydroxide has a high specific surface area, and can adsorb colloid, suspended solids, dyes and organic substances in sewage on its surface.

Aluminum Trihydroxide can neutralize gastric acid and is non-toxic, for which it is always used as the traditional medicine for the treatment of stomach.
Aluminum Trihydroxide has high whiteness, ultrafine particle size as well as complete crystal form, and has a strong compatibility with brightening agent.
Aluminum Trihydroxide, as an additive coating and resin, can effectively improve the whiteness, opacity, smoothness and ink absorption of coated paper.

Aluminum Trihydroxide synthesized by hydrothermal method has the advantages of high purity, small particle size, uniform distribution, easily-controlling crystal form and simple operation therefore, this method is widely used in the process of synthesis of Aluminum Trihydroxide.
Aluminum Trihydroxide has plenty of applications; some people believe that these uses are really endless.
Aluminum Trihydroxide, we can obtain various target products with diffrernt surface area, pore volume, pore structure and crystal structure by controlling the temperature, concentration and pH of the reactants, which can be effectively used as a catalyst carrier for the hydrogenation of unsaturated carbonyl compounds and the preparation of fullerenes and the like.

Release to the environment of Aluminum Trihydroxide can occur from industrial use: formulation of mixtures, formulation in materials, manufacturing of the substance, in the production of articles and as an intermediate step in further manufacturing of another substance (use of intermediates).
Other release to the environment of Aluminum Trihydroxide is likely to occur from: indoor use in long-life materials with low release rate, outdoor use in long-life materials with low release rate, indoor use and outdoor use.

Aluminum Trihydroxide (Al(OH)3) has several medical applications.
Aluminum Trihydroxide is used as an antacid for treating heartburn as well as acid indigestion (reflux oesophagitis).
Aluminum Trihydroxide is also known to have healing properties of peptic ulcers.

In patients suffering from kidney failure, who show elevated serum phosphate levels (hyperphosphataemia), Aluminum Trihydroxide is used as a phosphate binder.
Aluminum Trihydroxide is an amphoteric compound , which means it can react as a base or as an acid.

Aluminum Trihydroxide as an anti-acid, Aluminum Trihydroxide reacts with any excess stomach acid (mainly HCl) with the formation of AlCl3 and water.
Al(OH)3 + 3HCl → AlCl3 + 3H2O
Al(OH)3 is known to cause constipation, so formulations of anti-acids often include a combination with Mg2+ antacids.

Aluminum Trihydroxide can be found in complex articles, with no release intended: electrical batteries and accumulators, vehicles and machinery, mechanical appliances and electrical/electronic products.
Aluminum Trihydroxide can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), rubber (e.g. tyres, shoes, toys) and leAluminum Trihydroxideer (e.g. gloves, shoes, purses, furniture).

Widespread uses:
Aluminum Trihydroxide is used in the following products: inks and toners, coating products, fillers, putties, plasters, modelling clay, washing & cleaning products, adhesives and sealants, cosmetics and personal care products, lubricants and greases and polishes and waxes.
Aluminum Trihydroxide is used in the following areas: building & construction work, printing and recorded media reproduction, formulation of mixtures and/or re-packaging and agriculture, forestry and fishing.
Aluminum Trihydroxide is used for the manufacture of: textile, leAluminum Trihydroxideer or fur and wood and wood products.

Other release to the environment of Aluminum Trihydroxide is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Aluminum Trihydroxide is used in the following products: coating products, polymers, fillers, putties, plasters, modelling clay, leAluminum Trihydroxideer treatment products, pH regulators and water treatment products and water treatment chemicals.

Aluminum Trihydroxide has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of Aluminum Trihydroxide can occur from industrial use: formulation of mixtures, formulation in materials, in the production of articles, manufacturing of the substance and as an intermediate step in further manufacturing of another substance (use of intermediates).

Other release to the environment of Aluminum Trihydroxide is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leAluminum Trihydroxideer products, paper and cardboard products, electronic equipment).
Aluminum trihydroxide the applications mentioned earlier, aluminum trihydroxide has other uses as well.

Aluminum trihydroxide is used in the production of aluminum chemicals, ceramics, and glass.
Aluminum trihydroxide can also be used as a filler or pigment in paints, coatings, and plastics to improve their properties.
Aluminum trihydroxideis used in the following products: coating products, fillers, putties, plasters, modelling clay, polymers and washing & cleaning products.

Aluminum trihydroxide has an industrial use resulting in manufacture of another substance (use of intermediates).
Aluminum trihydroxide is used in the following areas: mining, building & construction work and formulation of mixtures and/or re-packaging.
Aluminum trihydroxide is used for the manufacture of: chemicals, furniture, plastic products and rubber products.

Aluminum trihydroxide is generally considered to be safe for human health and the environment, although it can be harmful if ingested or inhaled in large quantities.
Aluminum trihydroxide is not considered a hazardous waste and can be disposed of in landfills or recycled.
While aluminum trihydroxide is generally considered safe for use in various applications, excessive exposure to aluminum and its compounds can be harmful.

Inhalation of aluminum trihydroxide dust or fumes can cause respiratory irritation, while ingestion of large amounts can lead to gastrointestinal disturbances such as nausea, vomiting, and diarrhea.
Prolonged exposure to high levels of Aluminum trihydroxide may also cause neurological effects, such as impaired motor function and cognitive decline.
Aluminum trihydroxide is regulated by various organizations to ensure its safe use.

Aluminum trihydroxide is found in nature as the mineral gibbsite, which is a common constituent of bauxite ore.
Aluminum trihydroxide is also found in some mineral springs and volcanic regions.
Small amounts of aluminum trihydroxide are present in some foods and drinking water.

Aluminum trihydroxide is compatible with a wide range of materials, including plastics, rubbers, coatings, and adhesives.
Aluminum trihydroxide is often used as a filler or reinforcing agent in these materials to improve their mechanical properties and fire resistance.
Aluminum trihydroxide is produced on a large scale worldwide, with China being the largest producer.

Aluminum trihydroxide can be recycled through a process known as the Bayer process, which is also used to produce aluminum metal from bauxite ore.
In this process, the Aluminum Trihydroxide is dissolved in a strong alkali solution and precipitated as alumina, which can then be used to produce new aluminum products.
Aluminum trihydroxide is an effective flame retardant due to its ability to release water and carbon dioxide when exposed to heat.

Aluminum trihydroxide reaction can help to cool and dilute the flame, slowing down the combustion process and reducing the spread of fire.
Aluminum trihydroxide is commonly used as a flame retardant in building materials such as insulation, roofing, and wallboard also be used as a filler in concrete and other construction materials to improve their properties.
Aluminum trihydroxide is considered safe for use in food packaging and processing.

Aluminum trihydroxide is often used as a coating on food packaging materials to improve their barrier properties and prevent contamination.
Aluminum trihydroxide can interact with other substances in certain applications, such as in the presence of acids or alkaline solutions.
Aluminum trihydroxide to dissolve or form other compounds, which can affect its properties and performance.

Safety Profile:
Aluminum trihydroxide adjuvant is intended for use in parenteral vaccines and is generally regarded as nontoxic.
Aluminum trihydroxide may cause mild irritation, dryness, and dermatitis on skin contact.
Aluminum Trihydroxide adjuvant may also cause redness, conjunctivitis, and short-term mild irritation.

Aluminum trihydroxide and other flame retardants, there is growing interest in developing alternative materials that are more environmentally friendly and less toxic.
Some potential alternatives include phosphorus-based compounds, natural materials such as wool and cotton, and intumescent coatings that expand when exposed to heat.

Synonyms
Dialume
Trihydroxyaluminum
Aluminum trihydroxide
Gibbsite (Al(OH)3)
14762-49-3
MFCD00003420
CHEBI:33130
NSC-664400
Amphojel
Alugel
Aluminum Hydroxide powder
Aluminum hydroxide Wet Gel
Alugelibye
Calmogastrin
Tricreamalate
Alumigel
Amphogel
Higilite
Hydrafil
Liquigel
Trisogel
Alusal
Apyral
Martinal A
Amorphous alumina
Apyral B
Di-Gel Liquid
Martinal A/S
Martinal F-A
Trihydrated alumina
Apyral 2
Apyral 4
Apyral 8
Alolt 8
Higilite H 31S
Higilite H 32
Higilite H 42
Apyral 15
Apyral 24
Apyral 25
Apyral 40
Apyral 60
Apyral 90
Aluminum hydroxide (Al(OH)3)
Alolt 80
Alolt 90
Amberol ST 140F
Apyral 120
Apyral 120VAW
Hychol 705
Hydral 705
Hydral 710
Alcoa C 31
Alcoa C 33
Alcoa H 65
Hydrated aluminum oxide
AKP-DA
Alcoa 331
Alcoa 710
Alcoa AS 301
Alcoa A 325
Alcoa C 330
Alcoa C 331
Alcoa C 333
Alcoa C 385
Reheis F 1000
Aluminum oxide trihydrate
Aluminic acid (H3AlO3)
British aluminum AF 260
C 4d
BACO AF 260
AC 714KC
Aluminiumhydroxid
HSDB 575
P 30BF
Alumina, tabular
Alumina, calcined
GHA 331
GHA 332
GHA 431
aluminum;trihydrate
C 31C
C 31F
trihydroxidoaluminium
Dialume (TN)
EINECS 244-492-7
AC 450
AE 107
AF 260
C-31-F
ALterna GEL (TN)
Ground ATH, 9 mum
Aluminum hydroxide, CP
C 31
C 33
CI 77002
H 46
Coarse ATH, 90 mum
Ground ATH, 11 mum
Ground ATH, 15 mum
Ground ATH, 19 mum
aluminium(3+) hydroxide
aluminium(III) hydroxide
C.I. 77002
Aluminum hydroxide (USP)
Ground ATH, 3.6 mum
UNII-5QB0T2IUN0
A 3011
Aluminum hydroxide, 76.5%
Aluminum hydroxide, dried gel
Coarse ground ATH, 25 mum
Dried Aluminium Hydroxide Gel
Aluminium Hydroxide Nanopowder
CHEMBL1200706
Aluminum hydroxide, dried (USP)
Aluminum hydroxide, reagent grade
Aluminum oxide (Al2O3), hydrate
BCP04783
HY-B1521
Aluminum Hydroxide - ALUGEL A211
Aluminum Hydroxide - ALUGEL A215
Aluminum Hydroxide - ALUGEL A503
Aluminum Hydroxide - ALUGEL A611
Aluminum Hydroxide - ALUGEL A621
Aluminum Hydroxide - ALUGEL A651
Aluminum Hydroxide - ALUGEL A661
Aluminum Hydroxide - ALUGEL A671
Aluminum Hydroxide - ALUGEL A681
NSC664400
s4826
Dried aluminum hydroxide gel (JP17)
Aluminum hydroxide, dried [USP:JAN]
Aluminum hydroxide, puriss., 76.5%
CCG-266013
Ground ATH, Low Viscosity Grade, 20 mum
Ground ATH, Low Viscosity Grade, 22 mum
Aluminium trihydroxide, Ground ATH, 4 mum
Aluminium trihydroxide, Ground ATH, 6 mum
Aluminum hydroxide Gel, colloidal suspension
Aluminium trihydroxide, Ground ATH, 11 mum
Aluminium trihydroxide, Ground ATH, 14 mum
Aluminium trihydroxide, Ground ATH, 25 mum
Aluminum hydroxide, Vetec(TM) reagent grade
CS-0013311
Ground ATH, Low Viscosity Grade, 7.5 mum
Ground ATH,Viscosity Optimized Grade, 9 mum
Aluminium trihydroxide, Ground ATH, 8.5 mum
Aluminium trihydroxide, Unground ATH, 55 mum
Aluminium trihydroxide, Unground ATH, 95 mum
D02416
EC 244-492-7
Ground ATH,Viscosity Optimized Grade, 11 mum
Ground ATH,Viscosity Optimized Grade, 15 mum
Ground and high whiteness Alumina Trihydrate (ATH), 10 mum
Ground and high whiteness Alumina Trihydrate (ATH), 14 mum
Ground and high whiteness Alumina Trihydrate (ATH), 20 mum
Ground and high whiteness Alumina Trihydrate (ATH), 6 mum
Aluminum oxide hydrated, technical, >=64% Al2O3 basis, powder
ALUMINIUM TRIHYDRATE (ATH)
Aluminium trihydrate (ATH) is initially derived from bauxite ore, before being refined into a fine white powder.
Aluminium trihydrate (also known as ATH and aluminium trihydroxide, chemical formula Al (OH)3) is initially derived from bauxite ore, before being refined into a fine white powder.
Aluminium trihydrate (ATH) can be added to casting resins at an approximate maximum percentage of 200% by weight (e.g. 200g of filler powder to 100g of resin).

CAS: 8064-00-4
MF: AlH6O3
Mol File: 8064-00-4.mol

Doing so will reduce shrinkage, improve thermal stability considerably and result in a heavier more substantial feel to cast products however the resin will become harder to pour and reproduction of fine surface details will be impaired as the filler content is increased. Never count the weight of the filler powder in the mix ratio.

Aluminium trihydrate (ATH) is an inert, odourless filler powder than can be used to reduce shrinkage and add weight to cast polymer products.
Aluminium trihydrate (ATH) can also improve the fire resistant properties of the casting and reduce exothermic reaction.

Annual production of Aluminium trihydrate (ATH) is around 100 million tons which is nearly all produced through the Bayer process.
The Bayer process dissolves bauxite (Aluminium Ore) in sodium hydroxide at elevated temperatures.
Aluminium trihydrate (ATH) is then separated from the solids that remain after the heating process.
The solids remaining after the Alumina Trihydrate is removed is highly toxic and presents environmental issues.

Aluminium trihydrate (ATH), also known as aluminium trihydroxide or alumina trihydrate, is derived from bauxite ore.
This natural ore is refined to a fine white powder via the Bayer process.
After washing and drying Aluminium trihydrate (ATH) is used as the feedstock for a wide range of alumina chemicals.

Alumina Trihydrate (AI2O3•3H2O) is the most widely used flame retardant in the world due to its versatility and low cost.
Available in different particle sizes, Aluminium trihydrate (ATH) can be used in a wide range of polymers at processing temperatures below 220°C.
Aluminium trihydrate (ATH) is non-toxic, halogen-free, chemically inert, and has low abrasiveness.
Additional benefits are arc and track resistance in plastics exposed to electrical arcing, acid resistance, and smoke suppression.
At about 220°C, Aluminium trihydrate (ATH) begins to decompose endothermically releasing approximately 35% of its weight as water vapor.

AI2O3•3H2O + HEAT —–> AI2O3 + 3 H2O

Aluminium trihydrate (ATH) acts as heat sink thereby retarding pyrolysis and reducing the burning rate.
The water vapor released has an added effect of diluting combustion gases and toxic fumes.

Uses
Over 90% of all Aluminium trihydrate (ATH) produced is converted to Aluminium Oxide (alumina) that is used to manufacture aluminum.
As a flame retardant, Aluminium trihydrate (ATH) is chemically added to a polymer molecule or blended in with a polymer to suppress and reduce the spreading of a flame through a plastic.
Aluminium trihydrate (ATH) is also used as an antacid that can be ingested in order to buffer the pH within the stomach.

Specification of Aluminium trihydrate (ATH)
Al2O3: 64.7%
Fe2O3: 0.0205% max
SiO2: 0.025% max
Na2O (Total): 0.35% max
Al(OH)3: 99.8% max
Sp. gravity: 2.4 g/cc
LOD at 1100C: 0.4% max
Loss on ignition at 10500C: 34%
Residue on 325 Mesh: NIL
Average Particle Size: varies as per grade from 2 - 80 microns
Coatings: Silane, Stearic Acid

Synonyms
Aluminium trihydrate
Aluminum, trihydrate
DTXSID20421935
MXRIRQGCELJRSN-UHFFFAOYSA-N
ALUMINIUM TRIHYDRATE (ATH)
Aluminum trihydrate (ATH) is often associated with its role as a non-halogen flame retardant and smoke suppressant, and for good reason, as Aluminum trihydrate (ATH) is the largest selling fire retardant additive in the world.
Aluminum trihydrate (ATH), also known alumina trihydroxide, is a white, odorless, and insoluble powder with the chemical formula Al(OH)3.
Aluminum trihydrate (ATH), in its crystalline form, corundum, its hardness makes it suitable as an abrasive.

CAS Number: 21645-51-2
Molecular Formula: AlH3O3
EINECS Number: 244-492-7

Alumina Chemical & Castables is the leading developer & Processor of Aluminum trihydrate (ATH).
This Aluminum trihydrate (ATH) can be converted to aluminium oxide or alumina by calcination.
Of the common fillers used in Plastics, Rubber, FRP, SMC, DMC moulding and other polymers only Aluminum trihydrate (ATH) has flame retarding and smoke suppressing properties as well as being an economical resin extender.

Aluminum trihydrate (ATH) is the hydroxide salt form of aluminum designed for oral ingestion.
The high melting point of Aluminum trihydrate (ATH) makes it a good refractory material for lining high-temperature appliances like kilns, furnaces, incinerators, reactors of various sorts, and crucibles.
Aluminum trihydrate (ATH) is used as a baseforpigments, as a water repellent in textile coatings, and as an antacid in medicine.

Aluminum trihydrate (ATH) is soluble in hydrochloric or sulfuric acids or in sodiumhydroxide.
Aluminum trihydrate (ATH) is derived from the mineral bauxite and is a common compound in nature.
Aluminium trihydroxide, also known as alumina trihydrate is the most economic and widely used flame retardant and smoke suppressant in the plastics industry.

Aluminum hydroxide together are the major components of the aluminium ore bauxite.
Aluminum trihydrate (ATH) also forms a gelatinous precipitate in water.
Aluminum trihydrate (ATH) is to be added to casting resins / surface casting this will create a more heat resistant object and increase the fire retardant properties of the cast material.

Aluminum trihydrate (ATH) needs to be incorporated in high loading which can impair the mechanical and electrical properties of the polymer.
Aluminum trihydrate (ATH) is an inorganic salt used as an antacid.
Aluminum trihydrate (ATH) is sometimes used to treat, control, or manage high levels of phosphate in the body.

Aluminum trihydrate (ATH) is also used with a low phosphate diet to prevent the formation of phosphate urinary stones.
Aluminum trihydrate (ATH) is also found in personal care products and industrial applications.
Aluminum trihydrate (ATH) is used as an antacid and included as an adjuvant in some vaccines.

Aluminum trihydrate (ATH) acts as a flame retardant and smoke suppressor because of its thermodynamic properties.
Aluminum trihydrate (ATH) is endothermic dehydration cools the plastic & Rubber parts and dilute with water vapour those combustible gases that do escape.
Aluminum trihydrate (ATH) is an inorganic white fine crystalline, non-hygroscopic powder.

Aluminum is the most abundant metal in the earth's crust and is always found combined with other elements such as oxygen, silicon, and fluorine. (L739, L740, L756)
Aluminum trihydrate (ATH) is used in polyester resins however with increased attention being given to smoke & toxic fume emissions, Aluminum trihydrate (ATH) has found large volume application in vinyl as a low smoke, non toxic replacement for antimony and in polyurethane, latex, neoprene foam system, Rubber, wire & Cable insulation, vinyl walls & flooring coverings and epoxies.
Aluminium hydroxide is the most stable form of aluminium.

Aluminum trihydrate (ATH) is used for the relief of heartburn, sour stomach, acid indigestion, stomach ulcers, peptic ulcer pain, and to promote the healing of peptic ulcers.
Aluminum trihydrate (ATH), Al(OH)3, is found in nature as the mineral gibbsite (also known as hydrargillite) and its three much rarer polymorphs: bayerite, doyleite, and nordstrandite.
Aluminum trihydrate (ATH) is solubility in water and organic solvents is very low.

Aluminum trihydrate (ATH) is the largest flame retardant (FR) used in diverse end applications.
The remaining metal oxide residue has a high internal surface where sooty particles, respectively polycyclic aromatic hydrocarbons, are absorbed, making Aluminum trihydrate (ATH) also a smoke suppressant.
Aluminum trihydrate (ATH) widely use in Paper Industries as a whitening agent in place of titanium dioxide.

Aluminum trihydrate (ATH) is also use in Paints Industries.
Aluminum trihydrate (ATH) also finds use as a fire retardant filler for polymer applications.
Aluminum trihydrate (ATH) is selected for these applications because it is colorless (like most polymers), inexpensive, and has good fire retardant properties.

Aluminum trihydrate (ATH) decomposes at about 180 °C (356 °F), absorbing a considerable amount of heat in the process and giving off water vapour.
Aluminum trihydrate (ATH) can replace upto 25% of the Titanium dioxide pigment & therefore is an economical extender reducing production cost.
Aluminum trihydrate (ATH) is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions.

Aluminum trihydrate (ATH) used commercially is manufactured by the Bayer process which involves dissolving bauxite in sodium hydroxide at temperatures up to 270 °C (518 °F).
Aluminum trihydrate (ATH), also known as Aluminum trihydrate (ATH), aluminum trihydrate, aluminum hydrate, hydrated alumina, and hydrated aluminum oxide, is a white to whitish-yellow water-insoluble powder with a specific gravity of 2.42.
In plasticised PVC fine precipitated Aluminum trihydrate (ATH) is used as FR and smoke suppressant.

Aluminum trihydrate (ATH) is very effective as a smoke suppressant in a wide range of polymers, most especially in polyesters, acrylics, ethylene vinyl acetate, epoxies, polyvinyl chloride (PVC) and rubber.
Aluminum trihydrate (ATH) disassociates enough in many glaze types to be useful as a source of Al2O3 to the melt (the finer the particle size the better).
Aluminum trihydrate (ATH) stays in suspension better in glaze slurries and has better adhesive qualities also, using hydrated alumina in glazes and glasses can promote a fining operation by coalescing finely dispersed gas bubbles.

Coarser Aluminum trihydrate (ATH) types produced by grinding are used in large volume in thermoset applications.
Cast resins and glass fibre reinforced products like BMC (Bulk Moulding Compounds) and SMC (Sheet Moulding Compounds) are processed in electrical and electronic appliances as well as in construction applications.
Aluminum trihydrate (ATH) added to a glaze can also enhance the color of Cr-Al pinks.

Larger additions of fine material can impart matteness if the glaze is able to take it into solution (sourcing alumina from kaolin, feldspar and frits is obviously more practical since these decompose readily in glaze melts).
Aluminum trihydrate (ATH) is used as an antacid in humans and animals (mainly cats and dogs).
The oxide layer acts as a barrier protecting the polymer against further decomposition.

Aluminum trihydrate (ATH) is commercially available in grain sizes ranging from 0.5 – 80 µm in median particle size (D50).
In Halogen Free Flame Retardant (HFFR) wire and cables (W&C), one of the largest markets for Aluminum trihydrate (ATH), fine precipitated Aluminum trihydrate (ATH) is used in sheAluminum trihydrate (ATH)ing and insulation.
The working principle is based on the thermal decomposition of Aluminum trihydrate (ATH)into aluminium oxide and water.

Aluminum trihydrate (ATH) is preferred over other alternatives such as sodium bicarbonate because Al(OH)3, being insoluble, does not increase the pH of stomach above 7 and hence, does not trigger secretion of excess acid by the stomach.
Aluminum trihydrate (ATH) reacts with excess acid in the stomach, reducing the acidity of the stomach content, which may relieve the symptoms of ulcers, heartburn or dyspepsia.
Aluminum trihydrate (ATH) can cause constipation, because the aluminium ions inhibit the contractions of smooth muscle cells in the gastrointestinal tract, slowing peristalsis and lengthening the time needed for stool to pass through the colon.

Aluminum trihydrate (ATH) is formulated to minimize such effects through the inclusion of equal concentrations of magnesium hydroxide or magnesium carbonate, which have counterbalancing laxative effects.
Aluminium trihydrate (Aluminum trihydrate (ATH)) is initially derived from bauxite ore, before being refined into a fine white powder.
Aluminum trihydrate (ATH) is initially derived from bauxite ore, before being refined into a fine white powder.

The waste solid, bauxite tailings, is removed and Aluminum trihydrate (ATH) is precipitated from the remaining solution of sodium aluminate.
Aluminum trihydrate (ATH) is also used to control hyperphosphatemia (elevated phosphate, or phosphorus, levels in the blood) in people and animals suffering from kidney failure.
Vaccine formulations containing Aluminum trihydrate (ATH) stimulate the immune system by inducing the release of uric acid, an immunological danger signal.

Aluminum trihydrate (ATH) strongly attracts certain types of monocytes which differentiate into dendritic cells.
Aluminum trihydrate (ATH) is a feedstock for the manufacture of other aluminium compounds: calcined aluminas, aluminium sulfate, polyaluminium chloride, aluminium chloride, zeolites, sodium aluminate, activated alumina, and aluminium nitrate.
Aluminum trihydrate (ATH) increases in pH may inhibit the action of pepsin an increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects.

Aluminium trihydroxide is employed in acrylic rubbers and moulding, thermosetting resins, thermoplastic cable sheAluminum trihydrate (ATH)ing, PVC flooring etc.
Aluminum trihydrate (ATH) normally, the kidneys filter excess phosphate out from the blood, but kidney failure can cause phosphate to accumulate.
Aluminum trihydrate (ATH) salt, when ingested, binds to phosphate in the intestines and reduce the amount of phosphorus that can be absorbed.

Closely related are Aluminum trihydrate (ATH), AlO(OH), and aluminium oxide or alumina (Al2O3), the latter of which is also amphoteric.
Aluminum trihydrate (ATH) is amphoteric,it has both basic and acidic properties.

Aluminum trihydrate (ATH) is an electrical insulator, which means it doesn’t conduct electricity, and it also has relatively high thermal conductivity.
The chemical formula for Aluminum trihydrate (ATH) is Al(OH)₃.

Molar mass: 78.00 g/mol
Appearance: White amorphous powder
Density: 2.42 g/cm3, solid
Melting point: 300 °C (572 °F; 573 K)
Solubility in water: 0.0001 g/100 mL
Solubility product (Ksp): 3×10−34
Acidity (pKa): >7
Isoelectric point: 7.7
Boiling point: 2980℃[at 101 325 Pa]
vapor pressure: storage temp.: Store at +5°C to +30°C.
solubility: 0.0015g/l
Color: White
Specific Gravity: 2.42
PH Range: >7
PH: 8-9 (100g/l, H2O, 20℃)(slurry)

Aluminum trihydrate (ATH) won’t dissolve in water, but will dissolve only in bases and acids.
Aluminum trihydrate (ATH) to act as an amphoteric substance in water.
Aluminum trihydrate (ATH) will act as an acid. And if a strong acid is present, it will act as a strong base.

Aluminum trihydrate (ATH) gel crystallizes with time.
Precipitated Aluminum trihydrate (ATH) is included as an adjuvant in some vaccines (e.g. anthrax vaccine).
One of the well-known brands of Aluminum trihydrate (ATH) adjuvant is Alhydrogel, made by Brenntag Biosector.

Aluminum trihydrate (ATH) is sometimes called "alum", a term generally reserved for one of several sulfates.
Aluminum trihydrate (ATH) appears to contribute to induction of a good Th2 response, so is useful for immunizing against pAluminum trihydrate (ATH)ogens that are blocked by antibodies however, it has little capacity to stimulate cellular (Th1) immune responses, important for protection against many pAluminum trihydrate (ATH)ogens, nor is it useful when the antigen is peptide-based.

Aluminum trihydrate (ATH) gels can be dehydrated (e.g. using water-miscible non-aqueous solvents like ethanol) to form an amorphous aluminium hydroxide powder, which is readily soluble in acids.
Heating converts it to activated Aluminum trihydrate (ATH), which are used as desiccants, adsorbent in gas purification, and catalyst supports.
Aluminum trihydrate (ATH) should be handled with caution because its exposure can cause irritation however, only minor and residual injuries will be present.

As for flammability, Aluminum trihydrate (ATH) is not flammable and will not burn.
Aluminum trihydrate (ATH) is not reactive, therefore, it is stable in both fire and water conditions.
Aluminum trihydrate (ATH) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 000 to < 10 000 000 tonnes per annum.

Aluminum trihydrate (ATH) used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Aluminum trihydrate (ATH) can be also used to product sulfuric acid Aluminum, alum, aluminum fluoride and sodium aluminate, and to synthesize molecular sieve.
Aluminum trihydrate (ATH) gel and drying gel of Aluminum trihydrate (ATH) can be used in medicine as antacids to neutralize gastric acid and protect ulcer surface for the treatment of gastric and duodenal ulcer disease and hyperacidity.

Aluminum trihydrate (ATH) can be transformed into alumina after heated in the air for dehydration, which is important for alumina production.
The residue or bauxite tailings, which is mostly iron oxide, is highly caustic due to residual Aluminum trihydrate (ATH).
Aluminum trihydrate (ATH) was historically stored in lagoons; this led to the Ajka alumina plant accident in 2010 in Hungary, where a dam bursting led to the drowning of nine people.

Aluminum trihydrate (ATH), white solid, is a typical amphoteric hydroxide that is insoluble in water but soluble in acid or alkali.
Aluminum trihydrate (ATH) is a widely used chemical product, and it is mainly used as plastic and polymer fillers, blanket flame retardant and binder, epoxy resin filler, toothpaste fillers, glass ingredients as well as paper color fillers and coatings.

Production Method Of Aluminum trihydrate (ATH):
97% of the bauxite ores produced worldwide each year are treated with Bayer method to obtain Aluminum trihydrate (ATH).
Aluminum trihydrate (ATH) has a density of 2.42 g/cm3, a melting point of 300°C, and a Mohs hardness of 2.5-3.5.
Aluminum trihydrate (ATH) is insoluble in water and organic solvents, but it can dissolve in strong acids and bases.

Aluminum trihydrate (ATH) is a weak base and can act as a buffer in solution.
Aluminum trihydrate (ATH) is typically produced by the Bayer process, which involves extracting aluminum from bauxite ore through a series of chemical reactions.
The resulting Aluminum trihydrate (ATH) is then calcined (heated) to remove water and produce alumina, a precursor to aluminum metal.

Sodium aluminate solution and the aluminum sulfate solution are neutralized to pH 6.5 to produce Aluminum trihydrate (ATH) precipitate.
The obtained precipitate is washed with water, filtered and dried at 70-80℃ for 12 hours, and then crushed to prepare the Aluminum trihydrate (ATH) product.
A12O3+2NaOH→2NaAO2+H2O
Al2O3+3H2SO4→A12(SO4)3+3H2O

6NaAIO2+A12(SO4)3+12H2O→8Al(OH)3↓+3Na2SO4
Recycled aluminum chloride is dissolved in water, decolorized with activated carbon and filtered to remove impurities, and then react with sodium carbonate to produce raw Aluminum trihydrate (ATH).

The raw products are filtered, washed and dried to obtain the final Aluminum trihydrate (ATH) products.
2A1C13+3Na2CO3+3H2O→2AI(OH)3↓+6NaCl+3CO2↑

Metabolism Of Aluminum trihydrate (ATH):
Aluminum trihydrate (ATH) or oxide is slowly solubilised in the stomach and reacts with hydrochloric acid to form aluminium chloride and water.
Aluminum trihydrate (ATH), dihydroxyaluminium sodium carbonate and aluminium carbonate form carbon dioxide, and aluminium phosphate forms phosphoric acid.

Aluminum trihydrate (ATH) formed is absorbed and is rapidly excreted by the kidneys in patients with normal renal function.
Aluminum trihydrate (ATH) antacids also combine with dietary phosphate in the intestine forming insoluble, nonabsorbable aluminium phosphate which is excreted in the faeces.

Uses:
Aluminum trihydrate (ATH) widely used for plastics, rubber, resin, paint, paint and so on.
Aluminum trihydrate (ATH) used as the thickener for ink and the raw materials for manufacturing aluminum salt, enamel, ceramics, glassware and lubricant also used for the preparation of various catalyst carrier.
Just to illustrate the broadness of the uses, we can say that Aluminum trihydrate (ATH) is used as mordant in dyes, purifier for water, ingredient for cosmetics, and even in as an element for processes in photography.

Aluminum trihydrate (ATH) is also applications of minor character in ceramics and construction but the most important field where Aluminum trihydrate (ATH) is applied is medicine.
Aluminum trihydrate (ATH) used for printing inks, painting pigments, crayons and rubber packing.
Aluminum trihydrate (ATH) uses in waterproof fabric, ink, glassware, paper packing, mordant, purifying agent and also used in aluminum salt, lubricant manufacture.

Aluminum trihydrate (ATH) is used in the following products: cosmetics and personal care products, coating products, inks and toners, fillers, putties, plasters, modelling clay, pharmaceuticals, adhesives and sealants, washing & cleaning products, lubricants and greases and polishes and waxes.
Release to the environment of Aluminum trihydrate (ATH) can occur from industrial use: formulation of mixtures and formulation in materials.
Aluminum trihydrate (ATH) used for supporting catalyst and separating the vapor liquid.

Aluminum trihydrate (ATH) is also very useful because cement with Aluminum trihydrate (ATH) addition dries rapidly if it is being exposed to heat.
Aluminum trihydrate (ATH) is use as an antacid and vaccine adjuvant, Aluminum trihydrate (ATH) has also been used as a phosphate binder in patients with kidney disease and as a topical treatment for skin conditions such as diaper rash and poison ivy.
Aluminum trihydrate (ATH) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

On the stage of production of concrete Aluminum trihydrate (ATH) is added to cement.
Ceramics and glass of both industrial and home application is manufactured using Aluminum trihydrate (ATH).
The most useful feature of Aluminum trihydrate (ATH) when it is added to glass consists in the fact that it makes glass heat-resistant.

Aluminum trihydrate (ATH) is possible because, as have been already mentioned, Aluminum trihydrate (ATH) is not flammable and has high melting point.
Aluminum trihydrate (ATH) combined with polymers appears to be a very good fire retardant.
Aluminum trihydrate (ATH) is most frequently used for the production of lipsticks, make-ups, and other products for skin care.

Aluminum trihydrate (ATH) is used there because it is totally stable and non toxic for people.
Aluminum trihydrate (ATH) manufacturers of cosmetics also use Aluminum trihydrate (ATH) to produce cleansers for skin, suntan products, body lotions, and moisturizers.
Aluminum trihydrate (ATH) used for the preparation of refractory, glass and pottery, as well as precipitation pigment and waterproof fabric also used for the manufacture of aluminum salts.

Personal care products, for example, shampoos, toothpastes, deodorants and many others, also involve using of Aluminum trihydrate (ATH).
Aluminum trihydrate (ATH) is able to neutralize acids, it serves as a natural antacid.
Aluminum trihydrate (ATH) also has a very useful property as it stimulates the immune system of human.

Aluminum trihydrate (ATH), various vaccines, including those that are used to treat hepatitis B, hepatitis A, and tetanus, are prepared using Aluminum trihydrate (ATH).
Aluminum trihydrate (ATH) can be also used for the treatment of kidney patients who have high level of phosphates in blood due to renal failure.

Aluminum trihydrate (ATH) is also used by formulators as a humectant, and to soften, smooth, and protect the skin it helps control product viscosity often found in facial masks and make-up preparations.
Aluminum trihydrate (ATH) used in the industries of petroleum, chemical, fertilizer, natural gas and environmental protection for increasing the gas or liquid distribution points and protecting the low-strength catalyst.
Aluminum trihydrate (ATH) useful feature exists due to the ability of Aluminum trihydrate (ATH) to bind with phosphates.

Aluminum trihydrate (ATH), phosphates are flushed out of the human body easily.
Aluminum trihydrate (ATH) has many advantages including large-scale production, adequate raw materials, high product purity and good solubility in acid.
Aluminum trihydrate (ATH) can transform into alumina, which has high thermal chemical stability, thermal strength, creep resistance and dielectric properties and low thermal expansion coefficient.

Alumina is an important material for the synthesis of ceramics.
In the process of ceramic synthesis, we can control the phase formation of the composite by Aluminum trihydrate (ATH) activation and crystallization process controlling.
Aluminum trihydrate (ATH) can be used as an important raw material for the preparation of aluminum salts, such as barium aluminate, aluminum sulfate and so on.

Aluminum trihydrate (ATH) powder is commonly regarded as an ideal flame retardant filler for plastics, unsaturated polyester, rubber and other organic polymers because of its filling, flame retardant and smoke-eliminating functions and non-toxic property.
Flame retardant mechanism of Aluminum trihydrate (ATH) is as follows: when the temperature exceeds 200 ℃, the Aluminum trihydrate (ATH) begin to perform endothermic decomposition and release three crystal water, and its decomposition rate reaches the largest at 250℃.

Aluminum trihydrate (ATH) thereby inhibiting the polymer temperature rise, reducing its decomposition rate and only producing water vapor, not generating toxic and harmful gases.
Aluminum trihydrate (ATH) exists in water mainly in form of Al(OH)4-, which can precipitate toxic heavy metals in sewage by coprecipitation method to achieve the effect of water purification after further filter.
Sol-gel method is commonly used for the preparation of ultra-fine Aluminum trihydrate (ATH).

The most common sol-gel method for the preparation of Aluminum trihydrate (ATH) is the hydrolysis of aluminum salts and alkoxides in water, the mechanism of which is divided into two steps: 1)-OR group is hydrolyzed to produce-OH; 2) Al3+ reacts with –OH to separate Aluminum trihydrate (ATH) precipitation out.
Aluminum trihydrate (ATH) used as mordants and analysis reagents.
Aluminum trihydrate (ATH) used for the gravimetric determination of potassium content

Aluminum trihydrate (ATH) used as adsorbents, emulsifiers, ion exchangers, chromatographic analytes and mordants.
Aluminum trihydrate (ATH) gel can be used for the treatment of duodenal ulcer, gastric ulcer and hyperacidity embolism.
Aluminum trihydrate (ATH) is used as an antacid to treat heartburn, acid indigestion, and other gastrointestinal problems.

Aluminum trihydrate (ATH) is a commonly used flame retardant in plastics, rubbers, coatings, and other materials.
When exposed to heat, Aluminum trihydrate (ATH) decomposes to release water vapor and carbon dioxide, which help to cool and dilute the flame, slowing down the combustion process and reducing the spread of fire.
Aluminum trihydrate (ATH) works by neutralizing excess stomach acid, thereby reducing symptoms.

Aluminum trihydrate (ATH) is used as an adjuvant in some vaccines to enhance the immune response and improve vaccine effectiveness.
Aluminum trihydrate (ATH) works by stimulating the immune system to produce a stronger response to the vaccine antigen.
Aluminum trihydrate (ATH) is used in water treatment to remove impurities and improve water quality.

Aluminum trihydrate (ATH) is used as a filler in ceramics and glass to improve their strength and other properties.
Aluminum trihydrate (ATH) is used in the production of construction materials such as insulation, roofing, and wallboard as a flame retardant and filler.
Aluminum trihydrate (ATH) can be used as a topical treatment for skin conditions such as diaper rash and poison ivy.

Aluminum trihydrate (ATH) is used in a wide range of industries, including pharmaceuticals, water treatment, and flame retardants.
Aluminum trihydrate (ATH) is used as an antacid to neutralize excess stomach acid and as an adjuvant in vaccines to stimulate an immune response.
Aluminum trihydrate (ATH) precipitate down and control the size and morphology of products by adjusting the pH value and CO2 concentration.

Aluminum trihydrate (ATH), microemulsion is typically composed of surfactants, cosurfactants, solvents and water (or aqueous solution).
Aluminum trihydrate (ATH), microemulsion has many excellent properties such as ultra-low interfacial tension and high solubilization capacity.
The preparation of nano-materials by microemulsion technology can precisely control the crystal growth process of nano-materials, and the micro-emulsion ball can encapsulate the crystal particles to effectively prevent the agglomeration of nano-particles.

The Aluminum trihydrate (ATH) as adjuvant can also improve the immunogenicity of the vaccine, the action mechanism of which is as follows: Aluminum trihydrate (ATH) adsorbs antigen on its surface to allow the antigen slow release so that it can play the role of extending efficacy.
Aluminum trihydrate (ATH) has a high specific surface area, and can adsorb colloid, suspended solids, dyes and organic substances in sewage on its surface.
Aluminum trihydrate (ATH) can neutralize gastric acid and is non-toxic, for which it is always used as the traditional medicine for the treatment of stomach.

Aluminum trihydrate (ATH) has high whiteness, ultrafine particle size as well as complete crystal form, and has a strong compatibility with brightening agent.
Aluminum trihydrate (ATH), as an additive coating and resin, can effectively improve the whiteness, opacity, smoothness and ink absorption of coated paper.
Aluminum trihydrate (ATH) is used in the production of aluminum chemicals, such as aluminum sulfate and polyaluminum chloride, which are used in water treatment, paper production, and other applications.

Aluminum trihydrate (ATH) synthesized by hydrothermal method has the advantages of high purity, small particle size, uniform distribution, easily-controlling crystal form and simple operation therefore, this method is widely used in the process of synthesis of Aluminum trihydrate (ATH).
Aluminum trihydrate (ATH) is used in the following products: inks and toners, coating products, fillers, putties, plasters, modelling clay, washing & cleaning products, adhesives and sealants, cosmetics and personal care products, lubricants and greases and polishes and waxes.
Aluminum trihydrate (ATH) is used in the following areas: building & construction work, printing and recorded media reproduction, formulation of mixtures and/or re-packaging and agriculture, forestry and fishing.

Aluminum trihydrate (ATH) is used for the manufacture of: textile, leAluminum trihydrate (ATH)er or fur and wood and wood products.
Other release to the environment of Aluminum trihydrate (ATH) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Aluminum trihydrate (ATH) is used in the following products: coating products, polymers, fillers, putties, plasters, modelling clay, leAluminum trihydrate (ATH)er treatment products, pH regulators and water treatment products and water treatment chemicals.

Aluminum trihydrate (ATH) has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of Aluminum trihydrate (ATH) can occur from industrial use: formulation of mixtures, formulation in materials, in the production of articles, manufacturing of the substance and as an intermediate step in further manufacturing of another substance (use of intermediates).
Aluminum trihydrate (ATH) has plenty of applications; some people believe that these uses are really endless.

Aluminum trihydrate (ATH), we can obtain various target products with diffrernt surface area, pore volume, pore structure and crystal structure by controlling the temperature, concentration and pH of the reactants, which can be effectively used as a catalyst carrier for the hydrogenation of unsaturated carbonyl compounds and the preparation of fullerenes and the like.
Release to the environment of Aluminum trihydrate (ATH) can occur from industrial use: formulation of mixtures, formulation in materials, manufacturing of the substance, in the production of articles and as an intermediate step in further manufacturing of another substance (use of intermediates).
Other release to the environment of Aluminum trihydrate (ATH) is likely to occur from: indoor use in long-life materials with low release rate, outdoor use in long-life materials with low release rate, indoor use and outdoor use.

Aluminum trihydrate (ATH) can be used as a coagulant to help remove suspended solids, turbidity, and color from water.
Aluminum trihydrate (ATH) is used to prevent or slow down the spread of fire in plastics, fabrics, and building materials.
Aluminum trihydrate (ATH) is an inorganic compound used to make a product less transparent.

Aluminum trihydrate (ATH) used for preparing waterproof fabrics, inks, glass, paper fillers, mordant, purifying agent, various aluminum salts, etc.
Aluminum trihydrate (ATH) (Al(OH)3) has several medical applications.
Aluminum trihydrate (ATH) is used as an antacid for treating heartburn as well as acid indigestion (reflux oesophagitis).

Aluminum trihydrate (ATH) is also known to have healing properties of peptic ulcers.
In patients suffering from kidney failure, who show elevated serum phosphate levels (hyperphosphataemia), Aluminum trihydrate (ATH) is used as a phosphate binder.
Aluminum trihydrate (ATH) is an amphoteric compound , which means it can react as a base or as an acid.

Aluminum trihydrate (ATH) as an anti-acid, Aluminum trihydrate (ATH) reacts with any excess stomach acid (mainly HCl) with the formation of AlCl3 and water.
Al(OH)3 + 3HCl → AlCl3 + 3H2O.
Other release to the environment of Aluminum trihydrate (ATH) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leAluminum trihydrate (ATH)er products, paper and cardboard products, electronic equipment).

Aluminum trihydrate (ATH) the applications mentioned earlier, Aluminum trihydrate (ATH) has other uses as well.
Aluminum trihydrate (ATH) is used in the production of aluminum chemicals, ceramics, and glass.
Aluminum trihydrate (ATH) can also be used as a filler or pigment in paints, coatings, and plastics to improve their properties.

Aluminum trihydrate (ATH)is used in the following products: coating products, fillers, putties, plasters, modelling clay, polymers and washing & cleaning products.
Aluminum trihydrate (ATH) has an industrial use resulting in manufacture of another substance (use of intermediates).
Aluminum trihydrate (ATH) is used in the following areas: mining, building & construction work and formulation of mixtures and/or re-packaging.

Aluminum trihydrate (ATH) is used for the manufacture of: chemicals, furniture, plastic products and rubber products.
Aluminum trihydrate (ATH) is generally considered to be safe for human health and the environment, although it can be harmful if ingested or inhaled in large quantities.
Aluminum trihydrate (ATH) is not considered a hazardous waste and can be disposed of in landfills or recycled.

While Aluminum trihydrate (ATH) is generally considered safe for use in various applications, excessive exposure to aluminum and its compounds can be harmful.
Inhalation of Aluminum trihydrate (ATH) dust or fumes can cause respiratory irritation, while ingestion of large amounts can lead to gastrointestinal disturbances such as nausea, vomiting, and diarrhea.
Aluminum trihydrate (ATH) is also found in some mineral springs and volcanic regions.

Small amounts of Aluminum trihydrate (ATH) are present in some foods and drinking water.
Aluminum trihydrate (ATH) is compatible with a wide range of materials, including plastics, rubbers, coatings, and adhesives.
Aluminum trihydrate (ATH) is often used as a filler or reinforcing agent in these materials to improve their mechanical properties and fire resistance.

Aluminum trihydrate (ATH) is produced on a large scale worldwide, with China being the largest producer.
Aluminum trihydrate (ATH) can be recycled through a process known as the Bayer process, which is also used to produce aluminum metal from bauxite ore.
In this process, the Aluminum trihydrate (ATH) is dissolved in a strong alkali solution and precipitated as alumina, which can then be used to produce new aluminum products.

Aluminum trihydrate (ATH) is an effective flame retardant due to its ability to release water and carbon dioxide when exposed to heat.
Aluminum trihydrate (ATH) reaction can help to cool and dilute the flame, slowing down the combustion process and reducing the spread of fire.
Aluminum trihydrate (ATH) is commonly used as a flame retardant in building materials such as insulation, roofing, and wallboard also be used as a filler in concrete and other construction materials to improve their properties.

Aluminum trihydrate (ATH) is considered safe for use in food packaging and processing.
Aluminum trihydrate (ATH) is often used as a coating on food packaging materials to improve their barrier properties and prevent contamination.
Aluminum trihydrate (ATH) can interact with other substances in certain applications, such as in the presence of acids or alkaline solutions.

Aluminum trihydrate (ATH) to dissolve or form other compounds, which can affect its properties and performance.
Prolonged exposure to high levels of Aluminum trihydrate (ATH) may also cause neurological effects, such as impaired motor function and cognitive decline.
Aluminum trihydrate (ATH) is regulated by various organizations to ensure its safe use.

Al(OH)3 is known to cause constipation, so formulations of anti-acids often include a combination with Mg2+ antacids.
Aluminum trihydrate (ATH) can be found in complex articles, with no release intended: electrical batteries and accumulators, vehicles and machinery, mechanical appliances and electrical/electronic products.
Aluminum trihydrate (ATH) can be found in products with material based on: paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), rubber (e.g. tyres, shoes, toys) and leAluminum trihydrate (ATH)er (e.g. gloves, shoes, purses, furniture).

Safety Profile:
Aluminum trihydrate (ATH) adjuvant is intended for use in parenteral vaccines and is generally regarded as nontoxic.
Aluminum trihydrate (ATH) and other flame retardants, there is growing interest in developing alternative materials that are more environmentally friendly and less toxic.

Some potential alternatives include phosphorus-based compounds, natural materials such as wool and cotton, and intumescent coatings that expand when exposed to heat.
Aluminum trihydrate (ATH) may cause mild irritation, dryness, and dermatitis on skin contact.
Aluminum trihydrate (ATH) adjuvant may also cause redness, conjunctivitis, and short-term mild irritation.

Synonyms:
Dialume
Trihydroxyaluminum
Aluminum trihydrate (ATH)
Gibbsite (Al(OH)3)
14762-49-3
MFCD00003420
CHEBI:33130
NSC-664400
Amphojel
Alugel
Aluminum Hydroxide powder
Aluminum hydroxide Wet Gel
Alugelibye
Calmogastrin
Tricreamalate
Alumigel
Amphogel
Higilite
Hydrafil
Liquigel
Trisogel
Alusal
Apyral
Martinal A
Amorphous alumina
Apyral B
Di-Gel Liquid
Martinal A/S
Martinal F-A
Trihydrated alumina
Apyral 2
Apyral 4
Apyral 8
Alolt 8
Higilite H 31S
Higilite H 32
Higilite H 42
Apyral 15
Apyral 24
Apyral 25
Apyral 40
Apyral 60
Apyral 90
Aluminum hydroxide (Al(OH)3)
Alolt 80
Alolt 90
Amberol ST 140F
Apyral 120
Apyral 120VAW
Hychol 705
Hydral 705
Hydral 710
Alcoa C 31
Alcoa C 33
Alcoa H 65
Hydrated aluminum oxide
AKP-DA
Alcoa 331
Alcoa 710
Alcoa AS 301
Alcoa A 325
Alcoa C 330
Alcoa C 331
Alcoa C 333
Alcoa C 385
Reheis F 1000
Aluminum oxide trihydrate
Aluminic acid (H3AlO3)
British aluminum AF 260
C 4d
BACO AF 260
AC 714KC
Aluminiumhydroxid
HSDB 575
P 30BF
Alumina, tabular
Alumina, calcined
GHA 331
GHA 332
GHA 431
aluminum;trihydrate
C 31C
C 31F
trihydroxidoaluminium
Dialume (TN)
EINECS 244-492-7
AC 450
AE 107
AF 260
C-31-F
ALterna GEL (TN)
Ground ATH, 9 mum
Aluminum hydroxide, CP
C 31
C 33
CI 77002
H 46
Coarse ATH, 90 mum
Ground ATH, 11 mum
Ground ATH, 15 mum
Ground ATH, 19 mum
aluminium(3+) hydroxide
aluminium(III) hydroxide
C.I. 77002
Aluminum hydroxide (USP)
Ground ATH, 3.6 mum
UNII-5QB0T2IUN0
A 3011
Aluminum hydroxide, 76.5%
Aluminum hydroxide, dried gel
Coarse ground ATH, 25 mum
Dried Aluminium Hydroxide Gel
Aluminium Hydroxide Nanopowder
CHEMBL1200706
Aluminum hydroxide, dried (USP)
Aluminum hydroxide, reagent grade
Aluminum oxide (Al2O3), hydrate
BCP04783
HY-B1521
Aluminum Hydroxide - ALUGEL A211
Aluminum Hydroxide - ALUGEL A215
Aluminum Hydroxide - ALUGEL A503
Aluminum Hydroxide - ALUGEL A611
Aluminum Hydroxide - ALUGEL A621
Aluminum Hydroxide - ALUGEL A651
Aluminum Hydroxide - ALUGEL A661
Aluminum Hydroxide - ALUGEL A671
Aluminum Hydroxide - ALUGEL A681
NSC664400
s4826
Dried aluminum hydroxide gel (JP17)
Aluminum hydroxide, dried [USP:JAN]
Aluminum hydroxide, puriss., 76.5%
CCG-266013
Ground ATH, Low Viscosity Grade, 20 mum
Ground ATH, Low Viscosity Grade, 22 mum
Aluminium trihydroxide, Ground ATH, 4 mum
Aluminium trihydroxide, Ground ATH, 6 mum
Aluminum hydroxide Gel, colloidal suspension
Aluminium trihydroxide, Ground ATH, 11 mum
Aluminium trihydroxide, Ground ATH, 14 mum
Aluminium trihydroxide, Ground ATH, 25 mum
Aluminum hydroxide, Vetec(TM) reagent grade
CS-0013311
Ground ATH, Low Viscosity Grade, 7.5 mum
Ground ATH,Viscosity Optimized Grade, 9 mum
Aluminium trihydroxide, Ground ATH, 8.5 mum
Aluminium trihydroxide, Unground ATH, 55 mum
Aluminium trihydroxide, Unground ATH, 95 mum
D02416
EC 244-492-7
Ground ATH,Viscosity Optimized Grade, 11 mum
Ground ATH,Viscosity Optimized Grade, 15 mum
Ground and high whiteness Alumina Trihydrate (ATH), 10 mum
Ground and high whiteness Alumina Trihydrate (ATH), 14 mum
Ground and high whiteness Alumina Trihydrate (ATH), 20 mum
Ground and high whiteness Alumina Trihydrate (ATH), 6 mum
Aluminum oxide hydrated, technical, >=64% Al2O3 basis, powder
ALUMINIUM TRIHYDRATE (ATH)
Aluminium trihydrate (ATH) is a white, odorless, powdery, solid substance.
Aluminium trihydrate (ATH) demonstrates a very low solubility in water but is considered to be amphoteric, meaning it will dissolve in both acids or a strong alkali.
Aluminium trihydrate (ATH) is the most common mineral filler in the manufacture of solid surface.


CAS Number: 21645-51-2
EC Number: 244-492-7
Molecular Formula: AlH6O3


Aluminium trihydrate (ATH) is a white powder that has thermal characteristics that give translucency and whiteness to the product.
Aluminium trihydrate (ATH) is dry to the touch.
Solid surface as a homogeneous pigmented mass formed by the polymerization of thermostable resins and, basically, aluminum trihydrate as the mineral filler of the mixture.


Aluminium trihydrate (ATH) is chemically combined with three water molecules and has a high melting temperature.
Aluminium trihydrate (ATH) is initially derived from bauxite ore, before being refined into a fine white powder.
Aluminium trihydrate (also known as aluminium trihydroxide, chemical formula Al (OH)3) is initially derived from bauxite ore, before being refined into a fine white powder.


Aluminium trihydrate (ATH) is a high surface area alumina trihydrate product with a very precise, ultrafine particle size distribution.
Features and benefits include a lower cost replacement for precipitated Aluminium trihydrate (ATH); lower soluble soda and free moisture content; improved handling properties; dependable delivery; long-tern availability; exceptional brightness; excellent suspension; an economical halogen-free smoke suppressor/flame retardant.


Aluminium trihydrate (ATH) has a number of common names used throughout the chemical industry which include: Hydrate Alumina, Alumina Hydrate, Aluminium Tri Hydroxide, ATH, Aluminium Hydrate and Aluminium Hydroxide.
Aluminium trihydrate (ATH) as its more commonly known is an inexpensive filler powder that can be added to polyester gelcoats & resins for bulking out.


Doing so will reduce shrinkage, improve thermal stability considerably and result in a heavier more substantial feel to cast products however the resin will become harder to pour and reproduction of fine surface details will be impaired as the filler content is increased.
Aluminium trihydrate (ATH) also has a secondary use that if added to polyurethane it will provide a fire-retardancy.


Aluminium trihydrate (ATH) is an inert, odourless filler powder than can be used to reduce shrinkage and add weight to cast polymer products.
Aluminium trihydrate (ATH) can also improve the fire resistant properties of the casting and reduce exothermic reaction.
Aluminium trihydrate (ATH) can be added to casting resins at an approximate maximum percentage of 200% by weight (e.g. 200g of filler powder to 100g of resin).


The aluminium trihydrate (ATH) Market Size was valued at USD 1.56 billion in 2021.
The aluminium trihydrate (ATH) market industry is projected to grow from USD 1.63 Billion in 2022 to USD 2.89 billion by 2030, exhibiting a compound annual growth rate (CAGR) of 5.6% during the forecast period (2022 - 2030).


Growing demand for flame retardants across major industries and surging use of Aluminium trihydrate (ATH) in the paints and coatings industry are driving the market growth.
Aluminium trihydrate (ATH) are obtained by digestion of bauxite throughout the Bayer process.
Alumina trihydrate starts to remove constitution water above 180 ° C.


Water removal cools the surface and eliminates entry of oxygen, which confers flame retardant properties and smoke suppressant.
Accordingly Aluminium trihydrate (ATH) is a necessary raw material for products like rubber, polyurethane, polyester, silicone, thermoplastic, cables, etc. with fire retardant properties.
Aluminium trihydrate (ATH) is the hydrated oxide of aluminium.


Aluminium trihydrate (ATH) is separated from bauxite ore using the Bayer process, with average particle size ranging from 80-100 micron.
The block crystals of alumina hydrate impart good chemical reactivity.
Aluminium trihydrate (ATH) is white in color.
Aluminium trihydrate (ATH) is chemically designated as Al(OH)3.


Alumina Trihydrate (ATH) Flame Retardant Market size is forecast to reach $ 836.20 Million by 2025, after growing at a CAGR of 4.52% during 2020-2025.
The growth of the Aluminium trihydrate (ATH) Flame Retardant Market is due to fast growing construction sector and ever increasing electronics industry.


The consumption of Aluminium trihydrate (ATH) flame retardants in American region is high and clearly seen the growth, because the availability of low-priced raw materials and comparatively less labor cost.
Presence of major manufacturing firms in the electrical and electronic industry is estimated to positively affect the market owing to the increasing product launches by the companies.


Aluminium trihydrate (ATH) is a white, translucent powder that is also called Aluminium trihydrate (ATH).
Aluminium trihydrate (ATH) is obtained from Bauxite.
When Aluminium trihydrate (ATH) is strongly heated, alumina trihydrate will convert to Aluminum oxide with the release of water.


Aluminium trihydrate (ATH) is filler powder which is generally used with fast-cast resin products to alter the properties and bulk the material out.
Aluminium trihydrate (ATH) can be added to casting resins at an approximate maximum percentage of 200% by weight (e.g. 200g of filler powder to 100g of resin).


Aluminium trihydrate (ATH) is s a low-cost, inert, odourless filler powder that can be used to bulk out, reduce shrinkage, add weight and add fire retardancy to casting resins including polyurethane, epoxy and polyester.
Aluminium trihydrate (ATH) or Aluminium Hydroxide is the hydrated oxide of Aluminium.
Aluminium trihydrate (ATH)’s unique reactivity with acid, as well as a base, makes it a major raw material for many applications.


Aluminium trihydrate (ATH) is a non-abrasive powder with a Mohs' hardness index of 2.5 -3 and a specific gravity of 2.42.
Aluminium trihydrate (ATH) is a fine particle and easy disperse grade.
On heating to 200°C, Aluminium trihydrate (ATH) decomposes into 66% alumina and 34% water.
This irreversible process makes Aluminium trihydrate (ATH) an effective flame retardant.



USES and APPLICATIONS of ALUMINIUM TRIHYDRATE (ATH):
Aluminium trihydrate (ATH) (AI2O3•3H2O) is the most widely used flame retardant in the world due to its versatility and low cost.
Aluminium trihydrate (ATH) is available in different particle sizes, it can be used in a wide range of polymers at processing temperatures below 220°C.
Aluminium trihydrate (ATH) is non-toxic, halogen-free, chemically inert, and has low abrasiveness.


Additional benefits are arc and track resistance in plastics exposed to electrical arcing, acid resistance, and smoke suppression.
At about 220°C, Aluminium trihydrate (ATH) begins to decompose endothermically releasing approximately 35% of its weight as water vapor.
AI2O3•3H2O + HEAT —–> AI2O3 + 3 H2O
Aluminium trihydrate (ATH) acts as heat sink thereby retarding pyrolysis and reducing the burning rate.


The water vapor released has an added effect of diluting combustion gases and toxic fumes.
Over 90% of all Aluminium trihydrate (ATH) produced is converted to Aluminium Oxide (alumina) that is used to manufacture aluminum.
As a flame retardant, Aluminium trihydrate (ATH) is chemically added to a polymer molecule or blended in with a polymer to suppress and reduce the spreading of a flame through a plastic.


Aluminium trihydrate (ATH) is also used as an antacid that can be ingested in order to buffer the pH within the stomach.
The most common use of Aluminium trihydrate (ATH) is for the production of aluminum metal.
Aluminium trihydrate (ATH) is also used as a flame retardant and smoke suppressant filler in polymers such as rubber products and carpet backing.


Aluminium trihydrate (ATH), also known as alumina trihydrate is the most economic and widely used flame retardant and smoke suppressant in the plastics industry.
needs to be incorporated in high loading which can impair the mechanical and electrical properties of the polymer.
Aluminium trihydrate (ATH) is employed in acrylic rubbers and moulding, thermosetting resins, thermoplastic cable sheathing, PVC flooring etc.


Applications of Aluminium trihydrate (ATH) include wire and cable insulation, injection-molded polyolefins, coatings, adhesives, rubber goods, paper filler and coating, PVC, EPDM, EPR, ABS, XLPE and compression molded Thermosets.
Aluminium trihydrate (ATH) is a low-cost, inert, odourless filler powder than can be used to bulk-out, reduce shrinkage, add weight and add fire retardancy to casting resins including polyurethane, epoxy and polyester.


Aluminium trihydrate (ATH) widely use in Paper Industries as a whitening agent in place of titanium dioxide.
Aluminium trihydrate (ATH) is also use in Paints Industries.
Aluminium trihydrate (ATH)can replace upto 25% of the Titanium dioxide pigment & therefore is an economical extender reducing production cost.
Aluminium trihydrate (ATH) also is used in the ceramic industry, in the manufacture of enamel and pigments and catalyst for chemical reactions.


Aluminium trihydrate (ATH) of the Common filler used in Plastics, Rubber, FRP, SMC, DMC moulding and other polymers only Alumina Trihydrate has flame retarding and smoke suppressing properties as well as being an economical resin extender.
Alumina Chemical & Castables is the leading developer & Processor of Aluminium trihydrate (ATH).


Aluminium trihydrate (ATH) is used in polyester resins.
However with increased attention being given to smoke & toxic fume emissions, Aluminium trihydrate (ATH) has found large volume application in vinyl as a low smoke, non toxic replacement for antimony and in polyurethane, latex, neoprene foam system, Rubber, wire & Cable insulation, vinyl walls & flooring coverings and epoxies.


Aluminium trihydrate (ATH) acts as a flame retardant and smoke suppressor because of its thermodynamic properties. Aluminium trihydrate (ATH)'s endothermic dehydration cools the plastic & Rubber parts and dilute with water vapour those combustible gases that do escape.
The latter is probably the main phenomenon associated with smoke suppression other excellent performance include electrical and track resistance.


Aluminium trihydrate (ATH) is commercially used as a paper coating, water repellant, flame retardant and a filler in glass, inks, ceramics, cosmetics, detergents and plastics.
Aluminium trihydrate (ATH) is widely used in Paper Industries as a whitening agent in place of titanium dioxide.
Aluminium trihydrate (ATH) is also used in Paints Industries.


Aluminium trihydrate (ATH) can replace up to 25% of the Titanium dioxide pigment & therefore is an economical extender reducing production costs.
Aluminium trihydrate (ATH) is ideal for the manufacture of mortars used for floors with epoxy resins, polymer concrete parts, decorative resin parts, etc.


Aluminium Trihydrate (ATH) is a flame retardant and smoke suppressant.
Industrial uses of Aluminium trihydrate (ATH) include; thermoplastic, thermoset plastic (SMC/BMC, pultrusion/extrusion), elastomers, latex backing, coatings and sealants.
Aluminium trihydrate (ATH) is the most used flame retardant in the world by volume and its use of it will continue to grow as a flame retardant and smoke suppressant with companies moving away from bromine and halogenated flame retardants.


Aluminium trihydrate (ATH) is used as a filler for epoxy, urethane, or polyester resins, where fire retardant properties or increased thermal conductivity are required.
Aluminium trihydrate (ATH) Filler Powder is compatible with all popular casting resins, including polyurethane, epoxy and polyester.
Aluminium trihydrate (ATH) can be added to casting resins at an approximate maximum percentage of 200% by weight (e.g. 200g of filler powder to 100g of resin).


Doing so will reduce shrinkage, improve thermal stability considerably and result in a heavier more substantial feel to cast products however the resin will become harder to pour and reproduction of fine surface details will be impaired as the filler content is increased.
Never count the weight of the filler powder in the mix ratio.
Aluminium trihydrate (ATH) Filler Powder is compatible with all popular casting resins, including polyurethane, epoxy and polyester.


Aluminium trihydrate (ATH) is used as a base in the preparation of transparent lake pigments.
Aluminium trihydrate (ATH) is also used as an inert filler in paints and tends to increase the transparency of colors when dispersed in oils.
Aluminium trihydrate (ATH) is used commercially as a paper coating, flame retardant, water repellant, and as a filler in glass, ceramics, inks, detergents, cosmetics, and plastics.


Aluminium trihydrate (ATH) can react with a base as well as an acid, and finds use in many applications as raw material.
Aluminium trihydrate (ATH) is a highly refined, inert mineral flame retardant and smoke suppressant.
Aluminium trihydrate (ATH) is offering lower costs, greater flexibility and non toxic flame retardant solutions compared to bromine and halogenated flame retardants.


Utilizing proprietary grinding, classifying and surface modification technology, Cimbar Performance Minerals Polyfill/PolyJet series Aluminium trihydrate (ATH) offer a broad spectrum of products for any industrial application.
Aluminium trihydrate (ATH) is used in polyester resins.


However with increased attention being given to smoke & toxic fume emissions, Aluminium trihydrate (ATH) has found large volume applications in vinyl as a low smoke, non-toxic replacement for antimony and in polyurethane, latex, neoprene foam system, Rubber, wire & Cable insulation, vinyl walls & flooring coverings and epoxies.
Aluminium trihydrate (ATH) acts as a flame retardant and smoke suppressor because of its thermodynamic properties.


Aluminium trihydrate (ATH)'s endothermic dehydration cools the plastic & Rubber parts and dilutes with water vapour those combustible gases that do escape.
The latter is probably the main phenomenon associated with smoke suppression other excellent performances include electrical and track resistance.


Aluminium trihydrate (ATH) is a very white halogen-free flame retardant filler used in a number of applications utilising the different benefits the product provides.
Plastics and rubber Aluminium trihydrate (ATH) is compatible with a wide range of polymer types including thermoplastics, thermosets and elastomers and is used in a diverse range of applications like glass reinforced plastic (GRP), rubber carpet backing and latex flexible foams.


Aluminium trihydrate (ATH) enhances the fire resistance properties of the final polymer product.
Aluminium trihydrate (ATH) is used in the manufacturing of many inorganic chemicals like Non – ferric Alum, Poly Aluminium chloride, Aluminium fluoride, Sodium Aluminate, Catalysts, Glass etc.
Aluminium trihydrate (ATH) is used in the manufacture of many inorganic chemicals including Aluminium Sulphate, Poly Aluminium Chloride, Sodium


Aluminate, Aluminium Fluoride, Titanium Dioxide, Zeolites, Catalysts and Glass.
Aluminium trihydrate (ATH) is the most consumable and applicable inorganic additive flame retardant that not only resists firing but also prevents smoke, dropping or toxic gas.
So, Aluminium trihydrate (ATH) is widely used with a gradual increase of usage, in the sectors of hot solidifying and moulding plastic, synthetic rubber, coating and construction materials.


Aluminium trihydrate (ATH) is a flame retardant suitable to be used in several industries.
Aluminium trihydrate (ATH) is also used as an adsorbent, emulsifier, ion exchanger, mordant, antacid, and filter medium, manufacture of paper, ceramics, printing inks, detergents, for waterproofing fabrics and in dentifrices and antiperspirants.


Aluminium trihydrate (ATH) is also to be used in the production of aluminium chemicals, major products are alum (aluminium sulfate), poly aluminium chloride (PAC), sodium aluminate, zeolites, and aluminium fluoride.
Aluminium trihydrate (ATH) is used as raw material in the manufacturing of glass, glaze and frits, flame retardant and smoke suppressant in plastic like Fiberglass cables, rubber products and carpet backing, raw material for fertilizer, and fibre cement board products.


Aluminium trihydrate (ATH) is used as a paper extender, solvent and water paint, UV curable coatings, inks, adhesives, polishing and cleansing agent, mould wash and separating agent.
Aluminium trihydrate (ATH) also can be used as filler for cast polymer products such as onyx and solid surfaces.
Aluminium trihydrate (ATH) is produced by latest technology with superior quality, high purity and constant performance properties.


-Solid Surfacing uses of Aluminium trihydrate (ATH):
Aluminium trihydrate (ATH)’s superior whiteness makes it a preferred choice for manufacturers of solid surfacing and synthetic marble.
Solid surfacing is filled with Aluminium trihydrate (ATH) machines easily which is particularly beneficial when producing seamless surfacing.


-Applications of Aluminium trihydrate (ATH):
*Raw material for aluminium chemicals production.
*Flame-retardant filler in plastics and fiber cement board construction products.
*Specialty alumina production.


-Surface coatings use of Aluminium trihydrate (ATH):
In waterborne and solvent-based paints Aluminium trihydrate (ATH) extends TiO2 enabling a reduction of paint production costs and providing flame retardancy to the coating.
The weathering resistance provided by Aluminium trihydrate (ATH) means it performs well in exterior coatings.
Aluminium trihydrate (ATH) also controls gloss in coatings making it suitable for a variety of applications including powder and roof coatings.


-Special properties of Aluminium trihydrate (ATH):
The raw material used for the Aluminium trihydrate (ATH) products is from a high purity source.


-Composites:
Due to their good chemical resistance and physical properties, Aluminium trihydrate (ATH) is a basic raw material for the manufacture of solid surface.
The solid surface is a material widely used in sanitary, kitchen, hotels, hospitals, façade cladding and construction in general.


-Aluminium trihydrate (ATH) will provide:
*Abrasion resistance: due to its hardness of 3 on Mohs scale, ATH will increase the coating’s resistance to wear.
*Clarity: due to its fairly low refractive index, ATH becomes transparent when combined with certain binder systems.
*UV-curing compatibility: being transparent for UV radiation, ATH does not block the curing mechanism.


-Applications of Aluminium trihydrate (ATH):
*Aluminium trihydrate (ATH) is used as filler in Dough Molding Compounds.
*Aluminium trihydrate (ATH) is used as filler in Cable compounds
*Aluminium trihydrate (ATH) is used as filler in resin transfer molding.


-Aluminium Trihydrate is used in various industries as:
*A raw material in the production of Aluminium chemicals
*A raw material in the manufacture of glass and glazes
*A raw material in catalyst production
*A flame retardant and smoke suppressant filler in plastics (for example: Cables, rubber products and carpet backing)
*A raw material for fertilizers, and fiber cement board products
*An extender and bodying agent in paper, solvent- and water-borne paints, UV curable coatings, inks, and adhesives
*A polishing and cleansing agent
*Mould wash and separating agent
*A filler of cast polymer products such as onyx and solid surfaces



BENEFITS OF ALUMINIUM TRIHYDRATE (ATH):
1. Flame Retardant Filler of Plastic & Rubber.
2. Good Fire-retardant Effect.



PRODUCTION OF ALUMINIUM TRIHYDRATE (ATH):
Annual production of Aluminium trihydrate (ATH) is around 100 million tons which is nearly all produced through the Bayer process.
The Bayer process dissolves bauxite (Aluminium Ore) in sodium hydroxide at elevated temperatures.
Aluminium trihydrate (ATH) is then separated from the solids that remain after the heating process.



ALUMINIUM TRIHYDRATE (ATH) IS A SIDE STREAM OF ALUMINIUM PRODUCTION CHARACTERISED BY:
*High purity
*High whiteness
*Relatively low density of 2.4g/cm3 compared to other mineral fillers, which are typically at 2.7g/cm3
*Medium Mohs hardness of 3
*Decomposition around 180°C, releasing water.



ALUMINIUM TRIHYDRATE (ATH) / FLAME RETARDANT FILLER:
Aluminium trihydrate (ATH) is a white filling material that provides flame retardant and self-extinguishing properties for polyester resins and gelcoats.
Aluminium trihydrate (ATH) exposes water molecules within the body at high temperatures to reduce flame spread and smoke formation.
Aluminium trihydrate (ATH)is used in GRP pipe applications, in acrylic applications and in other multicomponent applications.



ALUMINIUM TRIHYDRATE (ATH) IS CHARACTERISED BY:
*high purity
*high whiteness
*relatively low density (2.4g/cm3) compared to other mineral *fillers (typically 2.7g/cm3)
*medium Mohs hardness of 3
*decomposition around 180oC, releasing water (making it an excellent halogen-free flame retardant)



PHYSICAL PROPERTIES OF ALUMINIUM TRIHYDRATE (ATH):
*Powdery substance
*Odorless
*Non-carcinogenic
*Contains thermal characteristic that provides translucency and whiteness to
*Solid surface material
*Non-smoking
*Low-toxicity
*Halogen-free
*Flame retardant



PHYSICAL AND CHEMICAL PROPERTIES OF ALUMINIUM TRIHYDRATE (ATH):
Aluminium trihydrate (ATH) is soluble in mineral acids and caustic soda.
Aluminium trihydrate (ATH) is insoluble in water.
Aluminium trihydrate (ATH) is fine grains.
Aluminium trihydrate (ATH) is no birefringence.
Aluminium trihydrate (ATH) is under plane-polarized light, particles are colorless with low relief



FOR THE CHOICE OF THE MOST SUITABLE ALUMINIUM TRIHYDRATE (ATH) FOR THE MANUFACTURE OF SOLID SURFACE WE MUST TAKE INTO ACCOUNT:
*particle size (grading):
Very thick particles will have a tendency to go to the bottom of the mixture.
On the contrary, the particles that are too thin may not disperse in the mixture.
*particle shape (milling):
If the particle is like a golf ball, the resin will stick easily.
If on the contrary, the particle is like a ping pong ball, it will be much more complicated.
*purity of the particles:
Avoid the presence of polluting particles that can generate black dots on the surface of the finished piece.
*silanization



WHY ARE MINERAL FILLERS USED FOR THE PRODUCTION OF POLYMERIC COMPOSITES?
The use of mineral fillers in the production of solid surfaces and polymeric composites has basically two objectives:
to provide the physical and mechanical properties required for the final product.
To a large extent it will be determined by the requirements and standards associated with the final product.
Thanks to the combination of different minerals we can:
modify the mechanical properties: hardness, abrasion, bending, etc…
lighten or increase the weight of the final product
improve conductive or anti-static properties
improve fire resistance
lower the cost of the mixture as fillers are cheaper than the resin itself.



FLAME RETARDANT MECHANISM OF ALUMINIUM TRIHYDRATE (ATH):
Aluminium trihydrate (ATH)decomposes when exposed to heat yielding aluminium oxide and water by the following reaction:
2Al(OH)3 --> Al2O3 + 3H2O
The decomposition starts at 180oC and is endothermic with a heat change of ~1050J/g.
A total loss of 34.7% of the original weight is observed.
When incorporated into organic materials such as plastics, textiles and wood, Aluminium trihydrate (ATH)acts a flame retardant by taking heat away from the flame front.
In addition the creation of water vapour near the surface of the polymer leads to oxygen depletion and reduces the burning rate of the gases.
Aluminium trihydrate (ATH) also promotes the formation of a char which prevents heat being returned back to the polymer.



SMOKE SUPPRESSION:
Smoke is the main cause of death in fire situations; one of the main advantages of using Aluminium trihydrate (ATH) in flame retardant formulations is to reduce smoke output.
A solid phase reaction occurs whereby the high surface area aluminium oxide formed from the decomposition of Aluminium trihydrate (ATH), absorbs the combustion products responsible for the formation of soot particles.



PHYSICAL and CHEMICAL PROPERTIES of ALUMINIUM TRIHYDRATE (ATH):
Physical Form: Powder
Particle Morphology: Hexagonal Platelet
Color: White
Specific Gravity g/cm3: 2.42
pH Value: 9 - 10
Hardness, Mohs: 2.5 – 3.5
Refractive Index: 1.57
Temperature of Decomposition: 220°C / 428°F
Heat of Decomposition, cal/g: 280
Theoretical loss on ignition, %: 34.6
Al2O3: 64.7%
Fe2O3: 0.0205% max
SiO2: 0.025% max
Na2O (Total): 0.35% max

Al(OH)3: 99.8% max
Sp. gravity: 2.4 g/cc
LOD at 1100C: 0.4% max
Loss on ignition at 10500C: 34%
Residue on 325 Mesh NIL
Average Particle Size: varies as per grade from 2 - 80 microns
Coatings: Silane, Stearic Acid
Molecular Weight : 81.028
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 0
Exact Mass: 81.0132325
Monoisotopic Mass: 81.0132325
Topological Polar Surface Area: 3 Ų
Heavy Atom Count: 4
Formal Charge: 0

Complexity: 0
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 4
Compound Is Canonicalized: Yes
Appearance: Power, dust.
Colour: White.
Odour: Odourless.
Solubility: Insoluble.
Initial boiling point and boiling range (°C): 2980°C at 760 mmHg.
Melting point (°C) decomposes before melting at >: 200°C.
Relative density: 2.44 @ 20°C.
Solubility Value: (G/100G) 0.000009.
Explosive properties: non explosive.
Other information: Particle Size (Micron) variable.



FIRST AID MEASURES of ALUMINIUM TRIHYDRATE (ATH):
-Description of first aid measures
*Inhalation:
Get medical attention if any discomfort continues.
*Ingestion:
Rinse mouth thoroughly and give plenty of water to drink.
Seek medical advice if necessary.
*Skin contact:
Clean by mechanical dry removal.
Subsequently rinse with water.
*Eye contact:
Immediately flush with plenty of water or eyewash solution for up to 10 minutes.
-Indication of any immediate medical attention and special treatment needed:
None



ACCIDENTAL RELEASE MEASURES of ALUMINIUM TRIHYDRATE (ATH):
-Personal precautions, protective equipment and emergency procedures:
Wear protective clothing.
-Environmental precautions:
No special environmental precautions required.
-Methods and material for containment and cleaning up:
Take up mechanically.
Dispose of absorbed material in accordance within local requlations



FIRE FIGHTING MEASURES of ALUMINIUM TRIHYDRATE (ATH):
-Extinguishing media:
*Extinguishing media:
The product is non-combustible.
Use fire-extinguishing media appropriate for surrounding materials.
*Unsuitable extinguishing media:
None
-Special hazards arising from the substance or mixture:
None.
-Advice for firefighters:
None



EXPOSURE CONTROLS/PERSONAL PROTECTION of ALUMINIUM TRIHYDRATE (ATH):
-Engineering measures:
Provide adequate general and local exhaust ventilation.
*Respiratory equipment:
If ventilation is insufficient, suitable respiratory equipment must be provided.
*Hand protection:
Wear suitable protective gloves conforming to EN 374.
*Eye protection Wear approved safety goggles.
-Other Protection:
Provide an eyewash station and safety shower.
*Hygiene measures:
When using do not eat, drink, or smoke.
*Environmental:
No special exposure controls required.



HANDLING and STORAGE of ALUMINIUM TRIHYDRATE (ATH):
-Conditions for safe storage, including any incompatibilities:
Dry storage at moderate temperatures.
-Specific end use(s):
See product information



STABILITY and REACTIVITY of ALUMINIUM TRIHYDRATE (ATH):
-Reactivity:
No specific reactivity hazards associated with this product.
-Chemical stability:
Stable under normal conditions of storage and use.
-Possibility of hazardous reactions:
Not determined.
-Hazardous Polymerisation:
Will not polymerise.
-Hazardous decomposition products:
No hazardous decomposition products.



SYNONYMS:
Alumina Trihydrate
Alumina Hydrate
Aluminium Tri Hydroxide
ATH
Aluminium Hydrate
Aluminium Hydroxide & ATH Mineral
Aluminium trihydrate
Aluminum, trihydrate
DTXSID20421935
153337-83-8
Hydrated alumina
Alumina trihydrate
ATH
Aluminum hydrate
Aluminum trihydrate
Alhydrogel
Ascriptin
Superfos
Amphogel
Aluminum (III) hydroxide
Amorphous alumina
Trihydrated Alumina
Trihydroxyaluminum
Tonerdehydrat
Hydrargillit
Bayerit
Böhmit
Diaspor
Nordstrandit
Aluminiumhydroxid
aluminum hydroxide
Pigment White 24
CI 7702
alumina hydrate
aluminum trihydrate
hydrated alumina
aluminium trihydrate
hydrated aluminum oxide
aluminum white
aluminum hydrate white
transparent white
gloss white
ALUMINIUM TRISTEARATE
Aluminium Tristearate About Aluminium tristearate Aluminium tristearate has not been registered under the REACH Regulation, therefore as yet ECHA has not received any data about this substance from registration dossiers. Aluminium tristearate is used at industrial sites. Uses of Aluminium Tristearate at industrial sites Aluminium tristearate is used in the following products: laboratory chemicals.Aluminium tristearate has an industrial use resulting in manufacture of another substance (use of intermediates). Aluminium tristearate is used in the following areas: formulation of mixtures and/or re-packaging. Release to the environment of Aluminium tristearate can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid. What Is Aluminium Tristearate? The Stearate salts, including Lithium Stearate, Aluminum Distearate, Aluminum Stearate, Aluminium Tristearate, Ammonium Stearate, Calcium Stearate, Magnesium Stearate, Potassium Stearate, Sodium Stearate, and Zinc Stearate are fine, white powders with a slight fatty odor. In cosmetics and personal care products, Stearate salts are used mainly in the formulation of makeup products such as eyeliner, eyeshadow, mascara, lipsticks, blushers, face powders and foundations. They are also used in fragrances, deodorants, and hair and skin care products. Why is it used in cosmetics and personal care products? The Stearate salts are generally used for their lubricating properties. They also help to keep emulsions from separating into their oil and liquid components. The Stearate salts increase the thickness of the lipid (oil) portion of cosmetics and personal care products and reduce the clear or transparent appearance of finished products. The commercial stearic acid from which the Stearate salts are manufactured is actually a mixture of monocarboxylic acids obtained from animal and/or vegetable sources. Synonyms and Related Terms aluminum tristearate; octadecanoic acid aluminum salt; stearic acid aluminum salt; Aluminium tristearate white (AAT); stéarate d'aluminium (Fr.) Other Properties Soluble in ethanol, benzene, turpentine and mineral oils. Odor: characteristic Use: Aluminium Stearate is commonly used as a paint and varnish dryer, waterproofing agent, defoaming agent, cement additive, in lubricants, cutting compounds, and in some food and pharmaceutical products. Potential Uses of Aluminium Tristearate: emollients emulsion stabilisers opacifying agents viscosity controlling agents The earliest and simplest oil paints were mixtures of pigments and drying oils. Eventually driers, resins, fillers, sometimes adulterants and suspension aids were also added. Aluminium tristearate was one of the components introduced in the 20th century. The gelling of oil solutions by aluminum soaps was known since at least the late 19th century but the use of Aluminium tristearate to alter the properties of paint did not come into use until much later. Church in 1901 mentions the use of "linoleate or oleate of alumina" to prevent the "subsidence" of vermilion in tubes (Church 1901), a comment not found in the 1890 edition (Church 1890). No further mention is made of this or similar materials until decades later even in Gardner's test protocols of 1911, the first of a series of books which would become the industry standard for paint analysis (Gardner 1911). Aluminium tristearate has been used to help suspend pigments in oil to prevent separation, to reduce the amount of oil needed to wet the pigment, and/or to increase the body of the paint by forming a gel with the oil thereby requiring less pigment. Research into the use of aluminum and zinc stearates as aids to grinding pigments and preventing settling or separation of pigment from vehicle (medium) resulted in a patent application in 1920 and issue of U.S. patent #1,421, 625 on July 23, 1922 to Clarence A. Ward. The Aluminium tristearate was added in a range of from 1 to 5% by weight. U.S. patent #1,428,273 describing a variation of this procedure but using unsaturated mineral oils as a vehicle and aluminum soaps (stearate, palmitate etc.) to "jellify" the oil was issued on September 5, 1922 to W. A. Collings. In regard to the wetting of pigments, the small amounts of free fatty acids normally present in pressed oils helped form soaps at the pigment interface, aided dispersion, and improved settling characteristics. Alkali refined linseed with its low free acid content created settling problems which were mediated by pigments precoated with metal soaps. Unlike calcium and zinc stearates that are available as 100% pure salts, the Aluminium tristearate as used in commerce is a non-stoichiometric compound. The trivalent aluminum may be united with one or two stearate anions with the balance of the charge being neutralized by hydroxyl anions (Elliott 1946; Pilpel 1971). Aqueous systems for the preparation or use of disalts seems to lead to a range of products containing varying amounts of stearate, hydroxyl, and water units. Anhydrous systems are needed to prepare stearates higher than the di-salt. Commercial preparations of Aluminium tristearate may also contain anywhere from 2 to 7% by weight free stearic acid (Pilpel 1971; Witco 1999). Analysis by weight of two commercial specimens by the author showed free stearic acid as 2 and 3% respectively. Early preparations may also contain significant amounts of palmitate (from palmitic acid) since the commercial stearic acid used in the preparation of metal soaps was often only 90% pure. Other fatty acids (palmitic, oleic, linoleic etc.) were also present as impurities. Product details of Aluminium tristearate Aluminium tristearate, also referred to as Aluminium Soap, has a variety of applications and uses, primarily as a thickener and a hydrophobic agent. See below for more details on the use of this product in different applications, which can include plastics, oil and gas additives, food and beverage, and various others. This product can be either vegetable or tallow based. Acme-Hardesty stocks the tallow based material, enabling us to complete your project quickly and efficiently. If you require vegetable based Aluminium tristearate material, please inquire about availability and lead times.Acme-Hardesty has been a leading provider of cost-effective solutions in the oleochemical industry for more than seven decades. We remain committed to helping customers and suppliers reach their specific operational goals. Our adherence to our core values of integrity, innovation and performance has enabled us to develop many enduring strategic alliances with companies in industries such as Food & Beverage, Cosmetics, Cleaners & Detergents, Metal Working Fluids, Renewable Chemistries, Surfactants and Esters, and many more. Uses and Applications of Aluminium tristearate Pigment Suspension and Thickening Agent in Paints, Enamels, Varnishes, Lacquers and Inks. Water Repellent for Leather, Rope and CementFood and Beverage: Aluminium tristearate is FDA Compliant for Food Contact as a Component of Adhesives, Resinous and Polymeric Coatings, Polymers, Adjuvants (Release Agents, Waxes and Dispersants) and as a Component of Paper or Paperboard in Contact with Aqueous and Fatty FoodsOil and Gas: Additive to Drilling Fluids to Release Gas BubblesPlastics: Lubricant in the Production of Polyamides and Thermosetting Plastics About Aluminium Tristearate Aluminium Tristearate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 to < 10 per annum. Aluminium Tristearate is used at industrial sites and in manufacturing. Chemical Properties White powder. Insoluble in water, alcohol, ether. Forms gel with aliphatic and aromatic hydrocarbons. Uses Thickener in paints, inks, and greases; water repellent; lubricant in plastics and cordage; and in cement production. Aluminium tristearate dissolves in vegetable oils on heating and if a high enough concentration of the soap is used, gelling occurs on cooling. In the usual practice of making paints, the Aluminium tristearate is ground with the pigment before the bulk of the oil is added. In a series of experiments Gardner tested the effects of metal soaps on pigments. Aluminium tristearate was found to coat the surface of pigment particles and helped prevent settling as well as reducing the amount of oil needed to wet the pigment. The amount of Aluminium tristearate needed to coat pigments varied on a weight basis, but a solution of 2% by weight (wt stearate/wt oil) Aluminium tristearate was more effective than 0.5% or 4% solutions in altering the surface (Gardner 1930). The soaps coat the surface of the pigments and by steric effects or electrical charge mechanisms keep the particles from aggregating (Pilpel 1966). This keeps the pigments in suspension. With increasing amounts of Aluminium tristearate the oil pigment mixture becomes viscous, and by using an appropriate amount of Aluminium tristearate the paint can gel at a lower pigment concentration (Mayer 1965). This can be used to create a "cheaper" paint since a smaller amount of a costly pigment needs to be used. A significant advantage of using stearates is that the oil and pigment do not separate greatly over long periods of time in the paint tube. Aluminium tristearate is an organic compound which is a salt of stearic acid and aluminium. It has the molecular formula Al(OH)2C18H35O2. It is also referred to as dihydroxy(octadecanoato-O-)aluminium or dihydroxy(stearato)aluminium. Aluminium tristearate is used to form gels in the packaging of pharmaceuticals, and in the preparation of colors for cosmetics. It is usually safe in commercial products, but aluminium may accumulate in the body. Properties of Aluminium Tristearate Chemical formula C18H37AlO4 Molar mass 344.472 g·mol−1 Antacids perform a neutralization reaction, ie. they buffer gastric acid, raising the pH to reduce acidity in the stomach. When gastric hydrochloric acid reaches the nerves in the gasitrointestinal mucosa, they signal pain to the central nervous system. This happens when these nerves are exposed, as in peptic ulcers. The gastric acid may also reach ulcers in the esophagus or the duodenum. Other mechanisms may contribute, such as the effect of aluminum ions inhibiting smooth muscle cell contraction and delaying gastric emptying. Aluminum is known to bind troponin C (a muscle protein) and to interfere with voltage-dependent calcium transport. Aluminum also binds to and inhibits the activity of mitochondrial voltage gated channels (VDAC). Description of Aluminium tristearate Aluminium tristearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2. Also known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging of pharmaceuticals and in the preparation of colors for cosmetics. While considered safe for use, extensive usage may result in aluminum accumulation. Aluminium Stearate (C54H105AlO6) exists as white powder and is an aluminum salt of stearic acid. In the pharmaceutical industry, it is used as an anticaking agent; colorant; emulsion stabilizer; and viscosity increasing agent. According to the FDA, aluminum stearate is considered safe for general or specific, limited use in food. Aluminium stearate is not classifiable as a human carcinogen (cancer-causing agent). Description Aluminium tristearate is a salt of stearic acid and aluminium. It is used to form gels in the packaging of pharmaceuticals, and in the preparation of colors for cosmetics. Aluminum is the most abundant metal in the earth's crust and is always found combined with other elements such as oxygen, silicon, and fluorine. (5, 6, 7) What is Aluminium Tristearate? Aluminium tristearate (C54H105AlO6) exists as white powder and is an aluminum salt of stearic acid. In the pharmaceutical industry, it is used as an anticaking agent; colorant; emulsion stabilizer; and viscosity increasing agent. According to the FDA, Aluminium tristearate is considered safe for general or specific, limited use in food. Aluminium tristearate is not classifiable as a human carcinogen (cancer-causing agent). Compound Type Aluminum Compound Household Toxin Industrial/Workplace Toxin Organic Compound Organometallic Synthetic Compound The commercial stearic acid from which the Stearate salts are manufactured is actually a mixture of monocarboxylic acids obtained from animal and/or vegetable sources. Aluminium tristearate is an organic compound which is a salt of stearic acid and aluminium. It has the molecular formula Al(OH)2C18H35O2. It is also referred to as dihydroxy(octadecanoato-O-)aluminium or dihydroxy(stearato)aluminium. It is used to form gels in the packaging of pharmaceuticals, and in the preparation of colors for cosmetics. It is usually safe in commercial products, but aluminium may accumulate in the body Aluminium tristearate (aluminum distearate) is a white, wax-like powder (metallic soap) that dissolves in mineral spirits or hot oil. A small amount (2% or less) added to oil paint imparts a short, buttery consistency. It eliminates the separation of pigment and oil, thickens varnishes considerably. A concentrate of Aluminium tristearate and linseed oil can be prepared ahead of time and added to the paint whenever needed. Aluminium tristearate is made via the precipitation process using high quality stearic acid and exhibits the following properties: Good gelling and thickening action, excellent water repellency, transparency and a synergistic effect with zinc stearate or calcium stearate. The effects of metal soaps on pigments have been extensively studied. Aluminium tristearate was found to coat the surface of pigment particles and helped prevent settling as well as reducing the amount of oil needed to wet the pigment. The amount of Aluminium tristearate needed to coat pigments varied on a weight basis, but a solution of 2% by weight (weight of Aluminium tristearate/weight of oil) of Aluminium tristearate was more effective than 0.5% or 4% solutions in altering pigment surfaces (Gardner 1930). The soaps coat the surface of the pigments and by steric effects keep the particles from aggregating (Pilpel 1963), which helps to keep the particles in suspension. With increasing amounts of Aluminium tristearate the oil pigment mixture becomes viscous, and by using an appropriate amount of Aluminium tristearate the paint can gel at a lower pigment concentration (Mayer 1965). This can be used to create a "cheaper" paint since a smaller amount of a costly pigment needs to be used. A significant advantage of using stearates is that the oil and pigment do not separate greatly over long periods of time in the paint tube. Manufacturers of artists' paints often use Aluminium tristearate in their formulations without listing it as a component on the product label. Solubility Aluminium tristearate exhibits relatively high solubility in hydrocarbon solvents (such as mineral spirits) when compared to other metallic stearates. It is insoluble in water, alcohol and ether; but is readily soluble in benzene, acids and common solvents when hot. Storage Aluminium tristearate has long storage life if stored in cool and dry location. USES of Aluminium Tristearate Aluminium tristearate is used to form gels in the packaging of pharmaceuticals, and in the preparation of colors for cosmetics. Use: Aluminium tristearate is one of numerous organo-metallic compounds sold by American Elements under the tradename AE Organo-Metallics™ for uses requiring non-aqueous solubility such as recent solar energy and water treatment applications. Similar results can sometimes also be achieved with Nanoparticles (also see Nanotechnology and Quantum Dots) and by thin film deposition. Note American Elements additionally supplies many materials as solutions. Aluminum Monostearate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. Additional technical, research and safety information is available. Use: Aluminium tristearate can be used in the preparation of colors for cosmetics and for the packaging of pharmaceuticals. Aluminium tristearate is the aluminum salt of the fatty acid, stearic acid. What Is Aluminium Tristearate? The Stearate salts, including Lithium Stearate, Aluminum Distearate, Aluminium tristearate, Aluminum Tristearate, Ammonium Stearate, Calcium Stearate, Magnesium Stearate, Potassium Stearate, Sodium Stearate, and Zinc Stearate are fine, white powders with a slight fatty odor. In cosmetics and personal care products, Stearate salts are used mainly in the formulation of makeup products such as eyeliner, eyeshadow, mascara, lipsticks, blushers, face powders and foundations. They are also used in fragrances, deodorants, and hair and skin care products. Why is it used in cosmetics and personal care products? The Stearate salts are generally used for their lubricating properties. They also help to keep emulsions from separating into their oil and liquid components. The Stearate salts increase the thickness of the lipid (oil) portion of cosmetics and personal care products and reduce the clear or transparent appearance of finished products. Aluminium tristearate is one of numerous organo-metallic compounds sold by American Elements under the trade name AE Organo-Metallics™ for uses requiring non-aqueous solubility such as recent solar energy and water treatment applications. Similar results can sometimes also be achieved with Nanoparticles and by thin film deposition. Note American Elements additionally supplies many materials as solutions. Aluminium tristearate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. Additional technical, research and safety information is available. Aluminium tristearate is a fine, bulky, odourless and colourless powder forming a plastic mass when heated, having the properties both of organic and inorganic matter. It embraces most of the characteristics of other metallic stearates and is regarded as the most important of these. Several studies of the material have already appeared in past years. The effects of metal soaps on pigments have been extensively studied. Aluminium tristearate was found to coat the surface of pigment particles and helped prevent settling as well as reducing the amount of oil needed to wet the pigment. The amount of Aluminium tristearate needed to coat pigments varied on a weight basis, but a solution of 2% by weight (weight of Aluminium tristearate/weight of oil) of Aluminium tristearate was more effective than 0.5% or 4% solutions in altering pigment surfaces. The soaps coat the surface of the pigments and by steric effects keep the particles from aggregating, which helps to keep the particles in suspension. With increasing amounts of Aluminium tristearate the oil pigment mixture becomes viscous, and by using an appropriate amount of Aluminium tristearate the paint can gel at a lower pigment concentration (Mayer 1965). This can be used to create a "cheaper" paint since a smaller amount of a costly pigment needs to be used. A significant advantage of using stearates is that the oil and pigment do not separate greatly over long periods of time in the paint tube. Manufacturers of artists' paints often use Aluminium tristearate in their formulations without listing it as a component on the product label. Description A hard, thermoplastic white powder prepared from Tallow and Alum. Aluminium tristearate forms gels with turpentine, Mineral spirits, and oils. It has been used as a Drier, thickener, Emulsifier, and matting agent in paints and varnishes although excess amounts produce soft, noncohesive films. Aluminium tristearate is also used to waterproof fabrics, ropes, Paper, Leather, Concrete, and Stucco. It is used as an ingredient in photographic emulsions. Aluminium tristearate is a white, wax-like powder (metallic soap) that dissolves in mineral spirits or hot oil. A small amount (2% or less) added to oil paint imparts a short, buttery consistency. It eliminates the separation of pigment and oil, thickens varnishes considerably. A concentrate of Aluminium tristearate and linseed oil can be prepared ahead of time and added to the paint whenever needed. Aluminium tristearate is made via the precipitation process using high quality stearic acid and exhibits the following properties: Good gelling and thickening action, excellent water repellency, transparency and a synergistic effect with zinc stearate or calcium stearate. Uses of Aluminium tristearate It has been used as a Drier, thickener, Emulsifier, and matting agent in paints and varnishes although excess amounts produce soft, noncohesive films. Aluminium tristearate is also used to waterproof fabrics, ropes, Paper, Leather, Concrete, and Stucco. It is used as an ingredient in photographic emulsions. Aluminium tristearate dissolves in vegetable oils on heating and if a high enough concentration of the soap is used, gelling occurs on cooling. In the usual practice of making paints, the Aluminium tristearate is ground with the pigment before the bulk of the oil is added. To prepare a concentrated solution (10% w/v), add 100 grams of Aluminium tristearate (nearly fills a half liter measuring cup without compacting) to one liter of linseed oil. Heat the oil to about 150° C. and gradually slowly adding the white powder to the hot oil with stirring. Add one part of this solution to four parts of oil by weight of oil before adding to pigments and grinding. There are multiple types of Aluminium tristearates, generally classified as aluminum mono-, di-, and tri-stearate. They vary in terms of physical properties such as melting point, free fatty acids, and particularly the gelling properties. Oils with a low viscosity are best thickened by aluminum di- and tri-stearate, whilst very viscous oils from stiffer gel when combined with aluminum mono- or di-stearates. All Aluminium tristearates are highly hydrophobic, and feature outstanding transparency and excellent adhesion to metal surfaces. Due to their water repellency, aluminum di- and tri-stearate are used as hydrophobic agents in the building industry. Aluminium tristearate (aluminum distearate) is a white, wax-like powder (metallic soap) that dissolves in mineral spirits or hot oil. A small amount (2% or less) added to oil paint imparts a short, buttery consistency. It eliminates the separation of pigment and oil, thickens varnishes considerably. A concentrate of Aluminium tristearate and linseed oil can be prepared ahead of time and added to the paint whenever needed. Aluminium tristearate is made via the precipitation process using high quality stearic acid and exhibits the following properties: Good gelling and thickening action, excellent water repellency, transparency and a synergistic effect with zinc stearate or calcium stearate. With increasing amounts of Aluminium tristearate the oil pigment mixture becomes viscous, and by using an appropriate amount of Aluminium tristearate the paint can gel at a lower pigment concentration (Mayer 1965). This can be used to create a "cheaper" paint since a smaller amount of a costly pigment needs to be used. A significant advantage of using stearates is that the oil and pigment do not separate greatly over long periods of time in the paint tube. Manufacturers of artists' paints often use Aluminium tristearate in their formulations without listing it as a component on the product label. Aluminium tristearate exhibits relatively high solubility in hydrocarbon solvents (such as mineral spirits) when compared to other metallic stearates. It is insoluble in water, alcohol and ether; but is readily soluble in benzene, acids and common solvents when hot. How to Use Aluminium tristearate dissolves in vegetable oils on heating and if a high enough concentration of the soap is used, gelling occurs on cooling. In the usual practice of making paints, the Aluminium tristearate is ground with the pigment before the bulk of the oil is added. To prepare a concentrated solution (10% w/v), add 100 grams of Aluminium tristearate (nearly fills a half liter measuring cup without compacting) to one liter of linseed oil. Heat the oil to about 150° C. and gradually slowly adding the white powder to the hot oil with stirring. Add one part of this solution to four parts of oil by weight of oil before adding to pigments and grinding. Aluminium tristearate (C54H105AlO6) exists as white powder and is an aluminum salt of stearic acid. In the pharmaceutical industry, it is used as an anticaking agent; colorant; emulsion stabilizer; and viscosity increasing agent. According to the FDA, Aluminium tristearate is considered safe for general or specific, limited use in food. Aluminium tristearate is not classifiable as a human carcinogen (cancer-causing agent). A hard, thermoplastic white powder prepared from Tallow and Alum. Aluminium tristearate forms gels with turpentine, Mineral spirits, and oils. It has been used as a Drier, thickener, Emulsifier, and matting agent in paints and varnishes although excess amounts produce soft, noncohesive films. Aluminium tristearate is also used to waterproof fabrics, ropes, Paper, Leather, Concrete, and Stucco. It is used as an ingredient in photographic emulsions. Aluminium tristearate exhibits relatively high solubility in hydrocarbon solvents (such as mineral spirits) when compared to other metallic stearates. It is insoluble in water, alcohol and ether; but is readily soluble in benzene, acids and common solvents when hot. Aluminium tristearate has long storage life if stored in cool and dry location. Aluminium tristearate dissolves in vegetable oils on heating and if a high enough concentration of the soap is used, gelling occurs on cooling. In the usual practice of making paints, the Aluminium tristearate is ground with the pigment before the bulk of the oil is added. To prepare a concentrated solution (10% w/v), add 100 grams of Aluminium tristearate (nearly fills a half liter measuring cup without compacting) to one liter of linseed oil. Heat the oil to about 150° C. and gradually slowly adding the white powder to the hot oil with stirring. Add one part of this solution to four parts of oil by weight of oil before adding to pigments and grinding. Use of Aluminium Tristearate: Aluminium Stearate is one of numerous organo-metallic compounds sold by American Elements under the tradename AE Organo-Metallics™ for uses requiring non-aqueous solubility such as recent solar energy and water treatment applications. Similar results can sometimes also be achieved with Nanoparticles (also see Nanotechnology and Quantum Dots) and by thin film deposition. Note American Elements additionally supplies many materials as solutions. Aluminum Stearate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. Additional technical, research and safety information is available.
ALUMINIUM ZIRCONIUM TETRACHLORHYDREX
EC / List no.: 231-208-1; Mol. formula: AlCl3; N° CAS : 7446-70-0; Nom INCI : ALUMINUM CHLORIDE,Nom chimique : Aluminium chloride, N° EINECS/ELINCS : 231-208-1, Aluminium chloride; ALUMINIUM CHLORIDE, ANHYDROUS; Aluminium Chloride Anhydrous; Aluminium chloride hexahydrate; Aluminium chloride,anhydrous; Aluminium tri-chloride; Aluminium Trichloride; Aluminium(III) chloride, anhydrous; Aluminum chloride; Aluminum chloride anhydrous; Aluminum Chloride, Anhydrous; Aluminum trichloride; Aluminum(III) Chloride; Alumnium chloride; anhydrous aluminium chloride; Chlorek glinu; trichloroalumane; Aluminium trichloride hydrated; Aluminiumchlorid; Aluminum chloride (8CI); Aluminum chloride (AlCl3) (9CI); Aluminum trichloride (AlCl3); TK Flock; Trichloroaluminumalluminio cloruro anidro (it); Alumiinikloridi, vedetön (fi); Alumiiniumkloriid, veevaba (et); aluminijev klorid, bezvodni (hr); aluminijev klorid, brezvodni (sl); aluminiumchlorid, vandfrit (da); Aluminiumchlorid, wasserfrei (de); aluminiumchloride, watervrij (nl); aluminiumklorid, vannfri (no); aluminiumklorid, vattenfri (sv); alumínium-klorid (vízmentes) (hu); alumīnija hlorīds, bezūdens (lv); chlorid hlinitý bezvodý (cs); chlorid hlinitý, bezvodý (sk); chlorure d'aluminium anhydre (fr); cloreto de alumínio anidro (pt); clorura de aluminiu, anhidra (ro); cloruro d'alluminio anidro (it); cloruro de aluminio anhidro (es); Trichlorek glinu, bezwodny (pl); άνυδρο τριχλωριούχο αργίλιο (el); алуминиев хлорид, безводен (bg) Anti-transpirant : Réduit la transpiration Astringent : Permet de resserrer les pores de la peau Déodorant : Réduit ou masque les odeurs corporelles désagréables. aliuminio chloridas, bevandenis (lt)
ALUMINUM CHLOROHYDRATE
DESCRIPTION:

Aluminium chlorohydrate is a group of water-soluble, specific aluminium salts having the general formula AlnCl3n−m(OH)m.
Aluminium chlorohydrate is used in cosmetics as an antiperspirant and as a coagulant in water purification.
In water purification, this compound is preferred in some cases because of its high charge, which makes it more effective at destabilizing and removing suspended materials than other aluminium salts such as aluminium sulfate, aluminium chloride and various forms of polyaluminium chloride (PAC) and polyaluminium chlorisulfate, in which the aluminium structure results in a lower net charge than aluminium chlorohydrate.

CAS: 12359-72-7
Molecular Formula: Al2ClH9O7
IUPAC Name: dialuminum;chloride;pentahydroxide;dihydrate


Aluminum Chlorohydrate is characterized by the highest aluminum concentration (23% Al2O3) in any commercially available aluminum-based solution.
Aluminum Chlorohydrate has a high cationic charge which makes it very effective at removing even very small particles required for drinking water purification.
In addition, Aluminum Chlorohydrate creates strong flocs that dewater well and leads to reduced levels of chemical sludge.


Because of the inherently high basicity (80-85%), Aluminum Chlorohydrate needs less alkalinity in the raw water than other coagulants.
As a result, Aluminum Chlorohydrate can be used in both high- and low-alkalinity waters, and it has very low impact on treated water alkalinity levels, so it decreases or eliminates the need for alkali addition.
Aluminum Chlorohydrate is made using high-quality raw materials and thus have very low levels of impurities, making it suitable for both drinking water applications and high demanding industrial applications.






Aluminum Chlorohydrate is a complex inorganic salt that consists of complex basic aluminumchloride described empirically as:
This complex is polymeric, loosely hydrated and encompasses a range of aluminum to chlorideratios from 2.1 down to but not including 1.9 to 1.
In the United States, Aluminum Chlorohydrate may be used as an active ingredient in OTC drug products.
When used as an active drug ingredient, the established name is Aluminum Chlorohydrate.

Aluminum Chlorohydrate basic aluminum (metal) salt consisting of aluminum, chloride and water.
Most widely used, very effective antiperspirant (reduces secretion of sweat) and deodorant (reduces bad odor by inhibiting bacterial growth).
Aluminum Chlorohydrate is very low irritant potency.

Further, the high degree of neutralization of the HCl results in minimal impact on treated water pH when compared to other aluminium and iron salts.

Aluminum Chlorohydrate is a common ingredient used in cosmetics, particularly in antiperspirants and deodorants.
Aluminum Chlorohydrate is an aluminum salt derived from chlorohydroxy acids and appears as a white, crystalline solid or a colorless liquid, depending on its formulation.
Aluminum Chlorohydrate functions as an antiperspirant agent by temporarily blocking sweat glands, reducing perspiration and odor.


Aluminum Chlorohydrate forms a gel-like plug in the sweat ducts, hindering the release of sweat onto the skin's surface.
Additionally, Aluminum Chlorohydrate is also gentle and non-irritating on the skin.
The chemical formula of Aluminum Chlorohydrate is Al2ClH9O7.



Aluminum Chlorohydrate finds significant use in both cosmetics and skincare products for different purposes.

Cosmetic products:
Aluminum Chlorohydrate is primarily employed as an antiperspirant agent.
Aluminum Chlorohydrate works by temporarily reducing sweat production, helping to control underarm wetness and odor.
This makes Aluminum Chlorohydrate a key ingredient in antiperspirant and deodorant formulations, providing individuals with a sense of dryness and freshness throughout the day

Skin care:
Aluminum Chlorohydrate is sometimes used in topical products targeting specific skin concerns.
Aluminum Chlorohydrate can be found in some acne treatments and astringents due to its ability to reduce excess oil and minimize pore size.
Additionally, Aluminum Chlorohydrate is occasionally included in products intended to address excessive sweating in other areas of the body, such as the palms or feet



ORIGIN OF ALUMINUM CHLOROHYDRATE:
Aluminum Chlorohydrate is typically produced by reacting aluminum hydroxide with hydrochloric acid.
The reaction results in the formation of aluminum chloride, which further reacts with water to form Aluminum Chlorohydrate.
The process involves careful control of temperature, pH, and concentration to obtain the desired product.


WHAT DOES ALUMINUM CHLOROHYDRATE DO IN A FORMULATION?
• Antiperspirant
• Deodorant


USES OF ALUMINIUM CHLOROHYDRATE:
Aluminium chlorohydrate is one of the most common active ingredients in commercial antiperspirants.
The variation most commonly used in deodorants and antiperspirants is Al2Cl(OH)5.
Aluminium chlorohydrate is also used as a coagulant in water and wastewater treatment processes to remove dissolved organic matter and colloidal particles present in suspension.


Alzheimer's disease:
Studies have found only a negligible association between exposure to and long-term use of antiperspirants and Alzheimer's disease.
There is no adequate evidence that exposure to aluminium in antiperspirants leads to progressive dementia and Alzheimer's disease.
Heather M. Snyder, the senior associate director of medical and scientific relations for the Alzheimer's Association, has stated, "There was a lot of research that looked at the link between Alzheimer's and aluminium, and there hasn't been any definitive evidence to suggest there is a link".


Breast cancer:
The International Journal of Fertility and Women's Medicine found no evidence that certain chemicals used in underarm cosmetics increase the risk of breast cancer.

Ted S. Gansler, the director of medical content for the American Cancer Society, stated "There is no convincing evidence that antiperspirant or deodorant use increases cancer risk".
However, there is continued concern over the use of aluminium chlorohydrate in cosmetics as the risk of toxic build up over time has not been ruled out.
The Scientific Committee on Consumer Safety (SCCS) is currently designing a study to analyse the build up of aluminium chlorohydrate via dermal penetration to assess the risk of toxic build up.


Aluminum Chlorohydrate 50% Solution is a widely used coagulant employed in water treatment processes.
Aluminum Chlorohydrate is also prevalent in personal care products, providing effective antiperspirant activity.

CHEMICAL PROPERTIES OF ALUMINUM CHLOROHYDRATE:
Aluminum Chlorohydrate, with its complex polymeric structure, is utilized for its ability to form flocs with particles in water, thus enhancing sedimentation processes and improving water clarity.

Appearance and Odor:
Aluminum Chlorohydrate commonly presents as a colorless to slightly yellowish liquid, typically odorless, and is known for its stability and efficacy in various applications.

pH and Density:
Aluminum Chlorohydrate 50% Solution usually has a mildly acidic pH and exhibits a density that is crucial for its effective function as a coagulant in water treatment processes.

Solubility:
Being soluble in water, Aluminum Chlorohydrate forms a slightly opalescent solution which is utilized in various applications for its coagulating and flocculating properties.


APPLICATIONS OF ALUMINUM CHLOROHYDRATE:
Aluminum Chlorohydrate 50% Solution is renowned for its varied applications in water treatment and personal care products.

Water Treatment:
Aluminum Chlorohydrate acts as a primary coagulant in water treatment processes where it facilitates particle aggregation and sedimentation, thereby enhancing water clarity and quality.

Personal Care Products:
In personal care, particularly in antiperspirants, Aluminum Chlorohydrate serves as an active ingredient that reduces perspiration by affecting sweat glands while being gentle on the skin.








STRUCTURE OF ALUMINIUM CHLOROHYDRATE:
Aluminium chlorohydrate is best described as an inorganic polymer and as such is difficult to structurally characterize.
However, techniques such as gel permeation chromatography, X-ray crystallography and 27Al-NMR have been used in research by various groups including that of Nazar and Laden to show that the material is based on Al13 units with a Keggin ion structure and that this base unit then undergoes complex transformations to form larger poly-aluminum complexes.


SYNTHESIS OF ALUMINIUM CHLOROHYDRATE:
Aluminium chlorohydrate can be commercially manufactured by reacting aluminium with hydrochloric acid.
A number of aluminium-containing raw materials can be used, including aluminium metal, alumina trihydrate, aluminium chloride, aluminium sulfate and combinations of these.
The products can contain by-product salts, such as sodium/calcium/magnesium chloride or sulfate.


Because of the explosion hazard related to hydrogen produced by the reaction of aluminium metal with hydrochloric acid, the most common industrial practice is to prepare a solution of aluminium chlorohydrate (ACH) by reacting aluminium hydroxide with hydrochloric acid.
The ACH product is reacted with aluminium ingots at 100 °C using steam in an open mixing tank.
The Al to ACH ratio and the time of reaction allowed determines the polymer form of the PAC n to m ratio.


KEY BENEFITS OF ALUMINIUM CHLOROHYDRATE:
Aluminium chlorohydrate is Extremely powerful and versatile coagulant
Aluminium chlorohydrate is Low impact on water alkalinity levels
Aluminium chlorohydrate is Reduced transportation and storage cost


Aluminium chlorohydrate is Minimal chemical sludge
Aluminium chlorohydrate Can be used in wide range of applications
Aluminium chlorohydrate has Optimized performance and reduce operating cost
Aluminium chlorohydrate has Robust performance with process variations







CHEMICAL AND PHYSICAL PROPERTIES OF ALUMINUM CHLOROHYDRATE:
Molecular Weight
210.48 g/mol
Hydrogen Bond Donor Count
7
Hydrogen Bond Acceptor Count
8
Rotatable Bond Count
0
Exact Mass
209.966757 g/mol
Monoisotopic Mass
209.966757 g/mol
Topological Polar Surface Area
7Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
0
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
10
Compound Is Canonicalized
Yes
Boiling Point, 100°C
pH, 3.0-5.0
Solubility, Soluble in water
Viscosity, High
Product Name
Aluminum Chlorohydrate
Structure
CAS
12042-91-0
Category
Main Products
Description
Basic aluminum (metal) salt consisting of aluminum, chloride and water.
IUPAC Name
Aluminum chloride hydroxide
Molecular Weight
174.45300
Molecular Formula
[Al2(OH)nCl6-n.xH2O]m(m≤10,n=1-5)
Boiling Point
100ºC at 760 mmHg
Solubility
Soluble in water or alcohol
Appearance
Off-white powder, no odor
Application
Antiperspirant & deodorant products as sticks, roll-ons, aerosols, creams, gels, sprays.
Storage
Store in a closed container at a dry place at room temperature
Composition
Aluminum chlorohydrate
Exact Mass
173.94600


SAFETY INFORMATION ABOUT ALUMINUM CHLOROHYDRATE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
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SYNONYMS OF ALUMINIUM CHLOROHYDRATE:
aluminum chlorhydroxide
aluminum oxychloride
PAX-18
PAX-18 cpd
Phosphonorm
poly(aluminum hydroxy)chloride
polyaluminium chloride
polyaluminum chloride
Aluminum chlorohydrate [USAN]
12359-72-7
Alchlordrate
Phosphonorm
Oristar alch
Sumalchlor 50
HYPERDROL
Takibine 1500
Reach 101
Reach 103
Reach 501
Pac 1000
DTXSID70154049
ALUMINUM CHLOROHYDRATE [INCI]
ALUMINUM HYDROXYCHLORIDE [MI]
ALUMINUM CHLOROHYDRATE DIHYDRATE
ALUMINIUM CHLOROHYDRATE [MART.]
DA-1097
ALUMINIUM CHLOROHYDRATE [WHO-DD]
ALUMINUM HYDROXYCHLORIDE [VANDF]
ALUMINUM CHLOROHYDRATE [USP IMPURITY]
ALUMINUM CHLOROHYDRATE [USP MONOGRAPH]
Aluminum chloride hydroxide (Al2Cl(OH)5), dihydrate
ALUMINUM CHLORIDE HYDROXIDE (AL2CL(OH)5), HYDRATE (1:2)


ALUMINUM HYDROXIDE
Aluminum Hydroxide's chemical formula is Al(OH)3.
Aluminum hydroxide is an inorganic salt used as an antacid.


CAS Number: 21645-51-2
EC Number: 244-492-7
MDL number: MFCD00003420
Molecular Formula: AlH3O3 / Al(OH)3



SYNONYMS:
Aluminic acid, Aluminic hydroxide, Aluminium(III) hydroxide, Aluminium hydroxide, Hydrated alumina, Orthoaluminic acid, Gibbsite, Hydrargillite, Algeldrate, Alu-Cap, Aludrox, Gaviscon, Pepsamar, Aluminium hydroxide, Trihydroxidoaluminium, Aluminic acid, Aluminic hydroxide, Alumanetriol, Aluminium(III) hydroxide, Aluminium hydroxide, Aluminium trihydroxide, Hydrated alumina, Orthoaluminic acid, Hydrated alumina, aluminum;trihydroxide, aluminum hydrate, Dried aluminium hydroxide, ALternaGEL, Aluminium hydroxide, dried, Alu-Cap, Alcoa C 30BF, Aluminum(III) hydroxide, Aluminum hydroxide, dried, Al(OH)3, ALGELDRATE ANHYDROUS, Dried aluminum hydroxide gel, 5QB0T2IUN0, Aluminum hydroxide gel, dried, Aluminium hydroxide gel, dried, ALUMINUM (AS HYDROXIDE), DTXSID2036405, AS04 COMPONENT ALUMINUM HYDROXIDE, FOAMCOAT COMPONENT ALUMINUM HYDROXIDE, FOAMICON COMPONENT ALUMINUM HYDROXIDE, GAVISCON COMPONENT ALUMINUM HYDROXIDE, ALUMINUM HYDROXIDE (II), ALUMINUM HYDROXIDE [II], ALUMINUM HYDROXIDE (MART.), ALUMINUM HYDROXIDE [MART.], Alum Adjuvant, ALUMINUM HYDROXIDE (USP IMPURITY), ALUMINUM HYDROXIDE [USP IMPURITY], ALUMINUM HYDROXIDE, DRIED (USP IMPURITY), ALUMINUM HYDROXIDE, DRIED [USP IMPURITY], DermaMed, Alumina hydrated, Aluminumhydroxide, aluminum hyroxide, Aluminio hidroxido, Alumina, Hydrated, aluminum trihydrate, Hydroxide, Aluminum, aluminium trihydroxide, ASTONEAGRAN, TENDERGRAN, 8064-00-4, Aluminum oxide hydrate, Hydroxyde d' aluminium, Amberol St. 140F, Aluminium oxide, hydrate, ALUMINII HYDROXIDUM, ALUMINUM OXIDE-3H2O, ALUMINUM HYDROXIDE [MI], DTXCID0016405, NIOSH/BD0708000, ALUMINUM OXIDE, TRIHYDRATE, Di-mu-hydroxytetrahydroxydialuminum, ALUMINUM HYDROXIDE [VANDF], ALUMINUM HYDROXIDE GEL,DRIED, ALUMINIUM HYDROXIDE DRIED GEL, ALUMINIUM HYDROXIDE [WHO-DD], ALUMINIUM HYDROXIDE [WHO-IP], AKOS015904617, Aluminum, di-mu-hydroxytetrahydroxydi-, DB06723, ALUMINUM HYDROXIDE [ORANGE BOOK], ALUMINUM (AS HYDROXIDE) [VANDF], ALUMINUM HYDROXIDE, DRIED [HSDB], ALUMINII HYDROXIDUM [WHO-IP LATIN], ALUMINUM HYDROXIDE GEL, DRIED [II], ALUMINUM HYDROXIDE GEL,DRIED [VANDF], BD07080000, DRIED ALUMINUM HYDROXIDE GEL [USP-RS], ALUMINUM HYDROXIDE COMPONENT OF FOAMCOAT, ALUMINUM HYDROXIDE COMPONENT OF FOAMICON, ALUMINUM HYDROXIDE COMPONENT OF GAVISCON, ALUMINIUM HYDROXIDE GEL, DRIED [WHO-DD], Q407125, J-014205, 8012-63-3



Aluminum Hydroxide, Al(OH)3, is found in nature as the mineral gibbsite (also known as hydrargillite) and its three much rarer polymorphs: bayerite, doyleite, and nordstrandite.
Aluminum Hydroxide is amphoteric, i.e., it has both basic and acidic properties.


Closely related are aluminium oxide hydroxide, AlO(OH), and aluminium oxide or alumina (Al2O3), the latter of which is also amphoteric.
These compounds together are the major components of the aluminium ore bauxite.
Aluminum Hydroxide also forms a gelatinous precipitate in water.


Aluminum Hydroxide's chemical formula is Al(OH)3.
Aluminum Hydroxide ıs a water-iinsoluble substance in the form of white powder, which is found in nature as a gibbsite mineral with monoclinic crystals has amphoteric properties, and forms salts in bases.


Amphoteric means that this compound displays both acidic and basic properties.
Although aluminum is the mist abundant metal and the third most abundant element, only a fraction of aluminum-containing materials (e.g. bauxite) is used for the production of aluminum hydroxide.


Aluminum hydroxide is the largest volüme flame retardant in the world.
Aluminum Hydroxide is made of aluminate solution through Bayer process, and is filtered.
In addition to behaving as a fire retardant, Aluminum Hydroxide is very effective as a smoke suppressant in a wide range of polymers, most especially in polyesters, acrylics, ethylene vinyl acetate, epoxies, polyvinyl chloride (PVC) and rubber.


Precipitated Aluminum Hydroxide is included as an adjuvant in some vaccines (e.g. anthrax vaccine).
One of the well-known brands of Aluminum Hydroxide adjuvant is Alhydrogel, made by Brenntag Biosector.
Since it absorbs protein well, Aluminum Hydroxide also functions to stabilize vaccines by preventing the proteins in the vaccine from precipitating or sticking to the walls of the container during storage.


Aluminum Hydroxide is sometimes called "alum", a term generally reserved for one of several sulfates.
Vaccine formulations containing Aluminum Hydroxide stimulate the immune system by inducing the release of uric acid, an immunological danger signal.
This strongly attracts certain types of monocytes which differentiate into dendritic cells.


The dendritic cells pick up the antigen, carry it to lymph nodes, and stimulate T cells and B cells.
Aluminum Hydroxide appears to contribute to induction of a good Th2 response, so is useful for immunizing against pathogens that are blocked by antibodies.
However, it has little capacity to stimulate cellular (Th1) immune responses, important for protection against many pathogens, nor is Aluminum Hydroxide useful when the antigen is peptide-based.


Aluminum hydroxide is an antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.
Aluminum hydroxide is an inorganic salt used as an antacid.
Aluminum Hydroxide is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions.


Subsequent increases in pH may inhibit the action of pepsin.
An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects.
Aluminum Hydroxide) is the amphoteric inorganic compound used as an antacid in the treatment of Duodenal, Peptic and Stomach Ulcer and some other conditions.


Aluminum Hydroxide is preferred over other alternatives such as sodium bicarbonate because Al(OH)3, being insoluble, does not increase the pH of stomach above 7 and hence, does not trigger secretion of excess acid by the stomach
However, with a little bit of digging, it turns out Aluminum Hyroxide often moonlights as a protective coating for UV filter superstar Titanium Dioxide.


Specifically, Aluminum Hydroxide protects our skin from the harmful effects of nasty Reactive Oxygen Species (free radicals derived from oxygen such as Superoxide and Hydrogen Peroxide) generated when Titanium Dioxide is exposed to UV light.
Btw, chlorine in swimming pool water depletes this protective coating, so one more reason to reapply your sunscreen after a dip in the pool on holiday.


Other than that, Aluminum Hydroxide also often shows up in composite pigment technologies where it is used the other way around (as the base material and not as the coating material) and helps to achieve higher color coverage with less pigment.
Aluminum hydroxide, also known as hydrated alumina, is a form of aluminum used as a colorant.


Aluminum Hydroxide is an orally active main form of aluminum used as adjuvant.
Aluminum hydroxide-based adjuvant researches include the repository effect, pro-phagocytic effect, and activation of the pro-inflammatory NLRP3 pathway.
Aluminum Hydroxide also acts as adjuvant to compensate low inherent immunogenicity of subunit vaccines.


Aluminum is a naturally occurring mineral.
Aluminum hydroxide is an antacid.


Aluminum Hydroxide is an inorganic compound containing aluminum.
Aluminum Hydroxide is used in various immunologic preparations to improve immunogenicity, aluminum hydroxide adjuvant consists of aluminum hydroxide gel in a saline solution.


In vaccines, Aluminum Hydroxide binds to the protein conjugate, resulting in improved antigen processing by the immune system.
Aluminum hydroxide is an antacid - a group of gastrointestinal drugs prepared in many forms such as capsules (475mg content); capsule (content 300mg, 500mg, 600mg); film-coated tablets (600mg strength) or suspension (320mg/5ml, 450mg/5ml, 600mg/5ml, 675mg/5ml).


When taken orally, aluminum chloride is the result of a slow reaction between aluminum hydroxide and hydrochloric acid in the stomach to be dissolved, a small amount is absorbed into the body.
Excess food causes the drug to pass out of the stomach more slowly, prolongs the reaction time of gastric hydrochloric acid with aluminum hydroxide, and causes the amount of aluminum chloride to increase higher.


In the small intestine, the process of digestion causes aluminum chloride to be rapidly converted into insoluble alkaline aluminum salts, poorly absorbed.
Aluminum salts can be a mixture of aluminum hydroxide, alkaline carbonate, oxyaluminum hydroxide and aluminum soap.
Phosphate in food also combines with aluminum hydroxide and also coordinates in the small intestine to form aluminum phosphate insoluble, not absorbed in the digestive tract and will be excreted in the feces.


Aluminum hydroxide is not metabolized.
In people with normal kidney function, only about 17-30% of the aluminum chloride formed is absorbed into the body and eliminated very quickly by the kidneys.


In patients with renal failure, there is a greater risk of aluminum accumulation (especially in the central nervous system and in the bones) leading to aluminum toxicity.
Absorbed aluminum will bind to serum proteins (eg, albumin, transferrin) so it will be difficult to remove by dialysis, most of the aluminum remaining in the digestive tract will form poorly absorbed aluminum salts and is excreted in the feces.


Aluminum hydroxide dry gel is an amorphous powder, insoluble in water or alcohol.
This powder contains up to 50 to 57% aluminum oxide as hydrated oxide and may contain varying amounts of aluminum carbonate and bicarbonate.
Aluminum hydroxide is an inorganic salt used as an ingredient in antacids.


Aluminum hydroxide reacts with excess hydrochloric acid in the stomach to reduce acid levels in the stomach, which is effective in reducing the symptoms of peptic ulcers, heartburn, heartburn or bloating, and acid reflux.
The nature of aluminum hydroxide causes constipation, so the drug is often taken with antacids containing magnesium (magnesium hydroxide or magnesium oxide) - this is a laxative effect.


Food phosphate in the stomach and intestines also binds with Aluminum hydroxide to form insoluble complexes and thereby reduce phosphate absorption.
Because of the above mechanism, aluminum hydroxide is also used to treat hyperphosphatemia in people with secondary hyperparathyroidism or renal failure.
Aluminum hydroxide is found in a variety of antacids.


Aluminum hydroxide, the formulation of which is Al(OH)3, can be found in nature in the following forms: gibbsite, which is a mineral, and doyleite, nordstrandite and bayerite, all of which are rare polymorphs.
Based on its properties, we can say that Aluminum Hydroxide appears to be an antacid.


Aluminum Hydroxide has various uses, primary among which is medical application.
Aluminum hydroxide is prepared by mixing aluminum chloride and ammonium hydroxide in two hydrometer cylinders.
Sodium hydroxide is used to dissolve the precipitate in one cylinder, hydrochloric acid in the other.


Aluminum hydroxide is a common compound of aluminum, hydrogen, and oxygen that can be considered either a base, with the formula Al(OH)3, or an acid, with the formula H3 AlO3.
Aluminum Hydroxide is frequently treated as a hydrate—a water-bonded compound—of aluminum oxide and designated variously as hydrated alumina, or aluminum hydrate or trihydrate, hydrated aluminum, or hydrated aluminum oxide, with the formula Al2 O3 (H2 0)x.


Normally, the kidneys filter excess phosphate out from the blood, but kidney failure can cause phosphate to accumulate.
The aluminium salt, when ingested, binds to phosphate in the intestines and reduce the amount of phosphorus that can be absorbed.
Aluminum hydroxide is an inorganic salt used as an antacid.


Aluminum Hydroxide is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions.
Subsequent increases in pH may inhibit the action of pepsin.
An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects.


Aluminum Hydroxide is an inorganic compound containing aluminum.
Used in various immunologic preparations to improve immunogenicity, aluminum hydroxide adjuvant consists of aluminum hydroxide gel in a saline solution.
In vaccines, Aluminum Hydroxide binds to the protein conjugate, resulting in improved antigen processing by the immune system.



USES and APPLICATIONS of ALUMINUM HYDROXIDE:
Aluminum hydroxide is used to treat heartburn, upset stomach, sour stomach, or acid indigestion.
Aluminum hydroxide is also used to reduce phosphate levels in people with certain kidney conditions.
Aluminum Hydroxide is an over-the-counter (OTC) product used as an antacid, and to treat peptic ulcer disease and hyperphosphatemia.


Aluminum hydroxide may also be used for purposes not listed in this medication guide.
Aluminum hydroxide has plenty of applications; some people believe that these uses are really endless.
Just to illustrate the broadness of the uses, we can say that aluminum hydroxide is used as mordant in dyes, purifier for water, ingredient for cosmetics, and even in as an element for processes in photography.


There are also applications of minor character in ceramics and construction.
But the most important field where aluminum hydroxide is applied is medicine.
Aluminum hydroxide is an antacid available over the counter and is used to relieve heartburn from gastrointestinal acidity associated with gastritis, peptic ulcers, ulcerative colitis, and gastroesophageal reflux disease (GERD).


Aluminum hydroxide is also used off-label to treat excessive phosphate levels in the blood (hyperphosphatemia) associated with chronic kidney disease.
Aluminum hydroxide works by neutralizing hydrochloric acid, the acid produced in the stomach, but it has no effect on acid production itself.
Aluminum hydroxide reacts with hydrochloric acid producing water and aluminum chloride, which is excreted in the stools.


By neutralizing stomach acid, aluminum hydroxide raises the pH level in the stomach, making it more alkaline, which inhibits the production and activity of pepsin, a stomach enzyme that breaks down dietary proteins and damages the stomach lining in peptic ulcer disease.
Reduction in the acidity of the stomach and reduced pepsin activity help heal peptic ulcers and also reduce acid reflux in the esophagus.


Aluminum hydroxide also binds to phosphates in the gastrointestinal tract and forms insoluble complexes that are eliminated in the feces. This prevents the absorption of dietary phosphate and helps reduce phosphate levels in the blood.
Aluminum hydroxide acts as an antacid and is most commonly used in the treatment of heartburn, gastritis, and peptic ulcer.


Aluminum Hydroxide is also sometimes used to reduce absorption of phosphorus for people with kidney failure.
Given how actively aluminum hydroxide is used in various fields we could not omit other field of its applications.
Apart from what we have already mentioned above, aluminum hydroxide, as well as any other aluminum compound, is used to purify water in order to remove particles and various kinds of impurities.


In manufacturing of inks aluminum hydroxide acts as an extender and preservative.
Aluminum hydroxide can be also used as chromatography in laboratories in order to separate chemicals into different compounds.
Most of Aluminum Hydroxide is converted to aluminium oxide (alumina) that is used in the manufacture of aluminium metal.


Aluminum Hydroxide is also used as a fire retardant filler, producing water vapor and smoke suppressant for polymer applications.
The gel form of Aluminum Hydroxide is applied to make aluminium salts as flocculants in water purification.
Aluminum Hydroxide is also used as an antacid, to treat/control, or manage high levels of phosphate in the body.


In addition Aluminum Hydroxide is also used with a low phosphate diet to prevent the formation of phosphate urinary stones.
Aluminum Hydroxide can also be found in personal care products.
Aluminum can in different forms be found in dental implants.


Areas of Use of Aluminum Hydroxide: Aluminum Sulphate, Poly Aluminum Chloride, Aluminum Fluoride, Zeolite, Sodium Aluminate, In Insulation and Insulation Industry, In Glass Industry, In Petrochemical Industry, In Textile Industry, In Paint Industry, and Flame Retardants (ATH- alumina trihydrate).
Certain areas where Aluminum Hydroxide is used; Insulation Industry, Glass Industry, Petrochemical Industry, Textile Indsutry, Paint Industry, Cable Indusrtry, Automotive Industry, and Rubber ındustry.


Aluminum hydroxide and its closely related compounds have a number of practical uses.
In one process of water purification, for example, aluminum sulfate, Al2 (SO4)3, or alum (usually potassium aluminum sulfate, KAl(SO4)2), is mixed with lime (calcium hydroxide, Ca(OH)2) in a container of water to be purified.


The reaction between these compounds forms the gelatinous precipitate aluminum hydroxide.
As the precipitate settles out of solution, it adsorbs on its surface particles of dirt and bacteria thatwere suspended in the impure water, which can then be removed by filtering off the aluminum hydroxide precipitate.


Aluminum Hydroxide is used as absorbent, in chromatography, manufacturing of glass, paper, inks, ceramics, lubricants, cosmetics.
Aluminum hydroxide is used as a desiccant powder, filler in paper, plastics, rubber and cosmetics.
Aluminum Hydroxide is used as a smoke suppressant and mordant dye.


Aluminum Hydroxide is also used in drugs as antacid and antihyperphosphatemic.
Aluminum Hydroxide is an important starting material for the preparation of other aluminum compounds, calcined alumina, aluminum sulfate, polyaluminum chloride, zeolites, sodium aluminate, activated alumina and aluminum nitrate.


In addition, Aluminum Hydroxide is used as a fire retardant.
Aluminum Hydroxide is used as filler in some artificial stone compound material, often in acrylic resin.
Aluminum Hydroxide is also used as a Claus catalyst support for waterproof fabrics.


Aluminum Hydroxide is also used to control hyperphosphatemia (elevated phosphate, or phosphorus, levels in the blood) in people and animals suffering from kidney failure.
Aluminum Hydroxide with many biomedical applications: as a gastric antacid, an antiperspirant, in dentifrices, as an emulsifier, as an adjuvant in bacterins and vaccines, in water purification, etc.


-Applications of Aluminum Hydroxide in medicine:
Given that aluminum hydroxide is able to neutralize acids, it serves as a natural antacid.
Aluminum hydroxide also has a very useful property as it stimulates the immune system of human.

Besides, various vaccines, including those that are used to treat hepatitis B, hepatitis A, and tetanus, are prepared using aluminum hydroxide.
Aluminum Hydroxide can be also used for the treatment of kidney patients who have high level of phosphates in blood due to renal failure.

This useful feature exists due to the ability of aluminum hydroxide to bind with phosphates.
After binding with aluminum hydroxide, phosphates are flushed out of the human body easily.


-Cosmetics application of Aluminum Hydroxide:
There are various applications for aluminum hydroxide in the field of cosmetics:
Aluminum hydroxide is most frequently used for the production of lipsticks, make-ups, and other products for skin care.

It is used there because Aluminum Hydroxide is totally stable and non toxic for people.
Sometimes aluminum hydroxide manufacturers of cosmetics also use aluminum hydroxide to produce cleansers for skin, suntan products, body lotions, and moisturizers.

Personal care products, for example, shampoos, toothpastes, deodorants and many others, also involve using of aluminum hydroxide.
Aluminum hydroxide is also sometimes used for protection of human skin.


-Application of Aluminum Hydroxide in industry:
Concrete could not be produced without aluminum hydroxide.
On the stage of production of concrete aluminum hydroxide is added to cement.

It is also very useful because cement with aluminum hydroxide addition dries rapidly if it is being exposed to heat.
Ceramics and glass of both industrial and home application is manufactured using aluminum hydroxide.

The most useful feature of aluminum hydroxide when it is added to glass consists in the fact that it makes glass heat-resistant.
It is possible because, as have been already mentioned, aluminum hydroxide is not flammable and has high melting point.
Aluminum hydroxide combined with polymers appears to be a very good fire retardant.


-Use of Aluminum Hydroxide in textile field:
Don’t forget that aluminum hydroxide doesn’t dissolve in water.
For this reason, Aluminum Hydroxide can be applied in textiles by adding it in order to produce waterproof clothes.

Besides, when it is needed to bind colors of vegetable dyes to fabric, aluminum hydroxide will also be very useful.
In this case, aluminum hydroxide is used as a mordant.

Any mordant is used in cases when fabrics are resistant to dyes.
In such situations, a mordant allows penetrating fabric by the dye.
Another instance of aluminum hydroxide usage is when it is used to make some dyes fire-resistant.


-Filler and fire retardant uses of Aluminum Hydroxide:
Aluminum Hydroxide finds use as a fire retardant filler for polymer applications.
Aluminum Hydroxide is selected for these applications because it is colorless (like most polymers), inexpensive, and has good fire retardant properties.

Aluminum Hydroxide and mixtures of huntite and hydromagnesite are used similarly.
Aluminum Hydroxide decomposes at about 180 °C (356 °F), absorbing a considerable amount of heat in the process and giving off water vapour.



PHARMACEUTICAL OF ALUMINUM HYDROXIDE:
Under the generic name "algeldrate", Aluminum Hydroxide is used as an antacid in humans and animals (mainly cats and dogs).
Aluminum Hydroxide is preferred over other alternatives such as sodium bicarbonate because Al(OH)3, being insoluble, does not increase the pH of stomach above 7, and hence does not trigger secretion of excess acid by the stomach.
Aluminum Hydroxide reacts with excess acid in the stomach, reducing the acidity of the stomach content, which may relieve the symptoms of ulcers, heartburn or dyspepsia.

Such products can cause constipation, because the aluminium ions inhibit the contractions of smooth muscle cells in the gastrointestinal tract, slowing peristalsis and lengthening the time needed for stool to pass through the colon.
Some such products are formulated to minimize such effects through the inclusion of equal concentrations of magnesium hydroxide or magnesium carbonate, which have counterbalancing laxative effects.



PROPERTIES OF ALUMINUM HYDROXIDE:
Aluminum hydroxide is found in nature as the mineral bayerite or gibbsite (also called hydrargillite).
Aluminum Hydroxide is a mixed aluminum oxide-hydroxide mineral is known as diaspore or boehmite.
In a purified form, aluminum hydroxide is either a bulky white powder or granules with a density of about 2.42 g/mL.

Aluminum Hydroxide is insoluble in water, but soluble in strong acids and bases.
In water, aluminum hydroxide behaves as an amphoteric substance.
That is, Aluminum Hydroxide acts as an acid in the presence of a strong base and as a base in the presence of a strong acid.

This behavior can be represented by the following somewhat oversimplified equation.
In the presence of a strong acid such as hydrochloric acid, the above equilibrium shifts to the right, and aluminum chloride is formed.
Al(OH)3 + 3 HCl → 3H2O + AlCl3

In the presence of a strong base such as sodium hydroxide, the equilibrium is driven to the left and a salt of the aluminate ion (AlO2–) is formed.
NaOH + H3AlO3 → NaAlO2 + 2H2O
Sodium aluminate, NaAlO2, has a number of practical applications, such as in water softening, paper sizing, soap and milk glass manufacture, and fabric and textile printing.

The purified aluminum hydroxide has form of bulky powder of white color or granules with density nearly 2.42 g per mL.
Aluminum hydroxide won’t dissolve in water, but will dissolve only in bases and acids.
You can expect aluminum hydroxide to act as an amphoteric substance in water.

If a strong base is present, aluminum hydroxide will act as an acid. And if a strong acid is present, Aluminum Hydroxide will act as a strong base.
Aluminum hydroxide should be handled with caution because its exposure can cause irritation.

However, only minor and residual injuries will be present.
As for flammability, aluminum hydroxide is not flammable and will not burn.
Besides, aluminum hydroxide is not reactive, therefore, it is stable in both fire and water conditions.



HOW DO YOU WRITE ALUMINUM HYDROXIDE?
Aluminum hydroxide is composed of three hydroxide anions and one aluminum cation.
The formula for aluminum hydroxide can be written as Al(OH)3



IS ALUMINUM HYDROXIDEA WEAK BASE?
Aluminum hydroxide is an amphiprotic compound.
Aluminum Hydroxide has the ability to act as an acid or as a base depending on the substance its reacting with.
Aluminum Hydroxide is a weak base when it reacts with a strong acid.
Aluminum Hydroxide doesn't dissociate completely to its respective ions.



WHAT DOOES ALUMINUM HYDROXIDE DO?
Aluminum hydroxide is composed of three hydroxide anions and one aluminum cation.
Aluminum Hydroxide is used mainly in medicine as an ingredient in antacids, which are drugs that help relieve the stomach, neutralize its acidity and treat heartburn.



CHEMICAL PROPERTIES OF ALUMINUM HYDROXIDE
There are many different forms of aluminum oxide, including both crystalline and non-crystalline forms.
Aluminum Hydroxide’s an electrical insulator, which means it doesn’t conduct electricity, and it also has relatively high thermal conductivity.
In addition, in its crystalline form, corundum, its hardness makes Aluminum Hydroxide suitable as an abrasive.

The high melting point of aluminum oxide makes Aluminum Hydroxide a good refractory material for lining high-temperature appliances like kilns, furnaces, incinerators, reactors of various sorts, and crucibles.
The chemical formula for aluminum hydroxide is Al(OH)₃.



PROPERTIES OF ALUMINUM HYDROXIDE
Aluminum Hydroxide is a highly water insoluble crystalline Aluminum source for uses compatible with higher (basic) pH environments.
Hydroxide, the OH- anion composed of an oxygen atom bonded to a hydrogen atom, is commonly present in nature and is one of the most widely studied molecules in physical chemistry.

Hydroxide compounds have diverse properties and uses, from base catalysis to detection of carbon dioxide.
In a watershed 2013 experiment, scientists at JILA (the Joint Institute for Laboratory Astrophysics) achieved evaporative cooling of compounds for the first time using hydroxide molecules, a discovery that may lead to new methods of controlling chemical reactions and could impact a range of disciplines, including atmospheric science and energy production technologies.

Aluminum Hydroxide is generally immediately available in most volumes.
Ultra high purity and high purity compositions improve both optical quality and usefulness as scientific standards.
Nanoscale elemental powders and suspensions, as alternative high surface area forms, may be considered.

American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.



STRUCTURE OF ALUMINUM HYDROXIDE
Aluminum Hydroxide is built up of double layers of hydroxyl groups with aluminium ions occupying two-thirds of the octahedral holes between the two layers.
Four polymorphs are recognized.
All feature layers of octahedral Aluminum Hydroxide units, with hydrogen bonds between the layers.
The polymorphs differ in terms of the stacking of the layers.

All forms of Al(OH)3 crystals are hexagonal [disputed – discuss]:
*gibbsite is also known as γ-Al(OH)3 or α-Al(OH)3
*bayerite is also known as α-Al(OH)3 or β-alumina trihydrate
*nordstrandite is also known as Al(OH)3
*doyleite

Hydrargillite, once thought to be Aluminum Hydroxide, is an aluminium phosphate.
Nonetheless, both gibbsite and hydrargillite refer to the same polymorphism of Aluminum Hydroxide, with gibbsite used most commonly in the United States and hydrargillite used more often in Europe.
Hydrargillite is named after the Greek words for water (hydra) and clay (argylles).



PROPERTIES OF ALUMINUM HYDROXIDE
Aluminum Hydroxide is amphoteric.
In acid, Aluminum Hydroxide acts as a Brønsted–Lowry base.
It neutralizes the acid, yielding a salt:

3 HCl + Al(OH)3 → AlCl3 + 3 H2O
In bases, Aluminum Hydroxide acts as a Lewis acid by binding hydroxide ions:
Al(OH)3 + OH− → [Al(OH)4]−



PRODUCTION OF ALUMINUM HYDROXIDE:
Virtually all the Aluminum Hydroxide used commercially is manufactured by the Bayer process which involves dissolving bauxite in sodium hydroxide at temperatures up to 270 °C (518 °F).
The waste solid, bauxite tailings, is removed and Aluminum Hydroxide is precipitated from the remaining solution of sodium aluminate.

This Aluminum Hydroxide can be converted to aluminium oxide or alumina by calcination.
The residue or bauxite tailings, which is mostly iron oxide, is highly caustic due to residual sodium hydroxide.
Aluminum Hydroxide was historically stored in lagoons; this led to the Ajka alumina plant accident in 2010 in Hungary, where a dam bursting led to the drowning of nine people.

An additional 122 sought treatment for chemical burns.
The mud contaminated 40 square kilometres (15 sq mi) of land and reached the Danube.
While the mud was considered non-toxic due to low levels of heavy metals, the associated slurry had a pH of 13.



PRECURSOR TO Al COMPOUNDS
Aluminum Hydroxide is a feedstock for the manufacture of other aluminium compounds: calcined aluminas, aluminium sulfate, polyaluminium chloride, aluminium chloride, zeolites, sodium aluminate, activated alumina, and aluminium nitrate.
Freshly precipitated Aluminum Hydroxide forms gels, which are the basis for the application of aluminium salts as flocculants in water purification.

This gel crystallizes with time.
Aluminum Hydroxide gels can be dehydrated (e.g. using water-miscible non-aqueous solvents like ethanol) to form an amorphous Aluminum Hydroxide powder, which is readily soluble in acids.
Heating converts Aluminum Hydroxide to activated aluminas, which are used as desiccants, adsorbent in gas purification, and catalyst supports.



HOW TO TAKE ALUMINUM HYDROXIDE?
You should take Aluminum Hydroxide only in the way this is specified on its label or how your doctor prescribes it.
Don’t exceed the dose prescribed by your doctor and don’t take aluminum hydroxide for longer than it was prescribed.

To be sure that your dose is accurate, measure Aluminum Hydroxide with medicine spoon or cup instead of regular spoon.
Don’t have a special medical device for measuring?
Buy it or ask your doctor to provide Aluminum Hydroxide.

Aluminum hydroxide should be taken with full glass of water.
Usually aluminum hydroxide is taken before bedtime or between meals.
Don’t take Aluminum Hydroxide longer than two months if your doctor hasn’t advised you otherwise.
Aluminum hydroxide should be stored away from heat, light, and moisture.

Don’t worry if you have missed a dose.
Usually aluminum hydroxide should not be taken regularly, but if it is, take it as soon as you remember about it.
But if the time for the next dose has almost come, skip the missed dose.

In case of an overdose with aluminum hydroxide, you should contact poison help service or seek emergency medical help.
The symptoms of an overdose with aluminum hydroxide are weight loss, mood changes, confusion, constipation, and urinating less than usually or not urinating at all.



REACTIONS IN HUMANS OF ALUMINUM HYDROXIDE:
Unlike some other aluminum compounds, aluminum hydroxide causes no adverse reaction in humans, at least towards the majority of persons.
Aluminum Hydroxide is very broadly used in many fields of life and has plenty of applications in home use and industry.
Most people may not know what aluminum hydroxide is or where this compound is used, but we already know it and useful features of aluminum hydroxide are obvious to all people interested in this subject.



MEDICAL PRECAUTIONS OF ALUMINUM HYDROXIDE:
There is no surprise that the most important application of aluminum hydroxide is its medical application.
Even though aluminum hydroxide is relatively safe to humans and is applied in various fields of human life, oral administration of aluminum hydroxide should be completed cautiously.

It is always recommended to advise your doctor before starting taking aluminum hydroxide or if any problems occur during the taking.
If you have any health problems related to kidneys, including stones, constipation or disease, you should see a doctor or get an advice of a pharmacist before taking any medicine that contains aluminum hydroxide.

Besides, the doctor’s advice is also necessary in case you are dehydrated or drink alcohol on a regular basis.
Taking aluminum hydroxide for more than two weeks with no advice of your doctor is strongly not recommended.
Besides, you should not take any other medications when taking aluminum hydroxide.

If you are pregnant or planning to become pregnant during your treatment with aluminum hydroxide, you must have an advice of your doctor.
The same should be done if you are a breast-feeding mother.
Effect of aluminum hydroxide on a nursing baby can be harmful.
For this reason, you should consult the doctor of yours in such a situation.



PHYSICAL and CHEMICAL PROPERTIES of ALUMINUM HYDROXIDE:
Chemical formula: Al(OH)3
Molar mass: 78.003 g·mol−1
Appearance: White amorphous powder
Density: 2.42 g/cm³ (solid)
Melting point: 300 °C (572 °F; 573 K)
Solubility in water: 0.0001 g/(100 mL)
Solubility product (Ksp): 3×10−34
Solubility: Soluble in acids and alkalis
Acidity (pKa): >7
Isoelectric point: 7.7
Thermochemistry
Std enthalpy of formation (ΔfH⦵298): −1277 kJ·mol−1

Molecular Properties
Molecular Weight: 78.004 g/mol
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 0
Exact Mass: 77.9897574 g/mol
Monoisotopic Mass: 77.9897574 g/mol
Topological Polar Surface Area: 3 Ų
Heavy Atom Count: 4
Formal Charge: 0
Complexity: 0
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0

Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 4
Compound Is Canonicalized: Yes
CAS Number: 21645-51-2
Molecular Weight: 78.00
EC Number: 244-492-7
MDL number: MFCD00003420
Physical Properties
Physical state: Solid
Color: White
Odor: Odorless

Melting point/freezing point: 300 °C (Elimination of water of crystallization)
Initial boiling point and boiling range: Not applicable
Flammability (solid, gas): The product is not flammable
Upper/lower flammability or explosive limits: Not applicable
Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: ca. 150 - 300 °C
pH: ca. 8 - 9 at 100 g/l at 20 °C (slurry)
Viscosity: No data available
Water solubility: Insoluble at 20 °C (OECD Test Guideline 105)
Partition coefficient: n-octanol/water: Not applicable for inorganic substances
Vapor pressure: < 0.1 hPa at 20 °C

Density: 2.42 g/cm³ at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: None
Other safety information: No data available
Chemical Formula: H3AlO3
Molecular Weight: 78 g/mol
Appearance: White powder
Melting Point: 300° C (572° F)
Boiling Point: N/A
Density: 2.42 g/cm³

Solubility in H2O: N/A
Exact Mass: 77.989757 g/mol
Monoisotopic Mass: 77.989757 g/mol
Physical Form: Granules
Quantity: 100 g
Assay Percent Range: 76.5% min.
Solubility Information: Soluble in alkaline aqueous solution,
hydrochloric acid, and sulfuric acid solution. Insoluble in water.
Formula Weight: 78
Grade: Reagent
Chemical Name or Material: Aluminum hydroxide


Identifiers:
CAS Number: 21645-51-2
IUPAC Name: Aluminium(3+) trihydroxide
Molecular Formula: AlH3O3
InChI Key: WNROFYMDJYEPJX-UHFFFAOYSA-K
SMILES: [OH-].[OH-].[OH-].[Al+3]
Molecular Weight (g/mol): 78.00
Synonyms: Amphojel, Alu-Cap, AlternaGel
MDL Number: MFCD00003420



FIRST AID MEASURES of ALUMINUM HYDROXIDE:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available



ACCIDENTAL RELEASE MEASURES of ALUMINUM HYDROXIDE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ALUMINUM HYDROXIDE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ALUMINUM HYDROXIDE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ALUMINUM HYDROXIDE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of ALUMINUM HYDROXIDE:
Reactivity
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid
no information available
-Incompatible materials
No data available


ALUMINUM STARCH OCTENYLSUCCINATE
Aluminum Starch Octenylsuccinate is a texture enhancing ingredient that is used in a variety of cosmetic and personal care products.
In its raw form, Aluminum Starch Octenylsuccinate has the appearance of a white powder that has no odor or smell.
Aluminum Starch Octenylsuccinate is also great for absorbing oil from the skin and giving it a flawless matte look.

CAS: 9087-61-0

Aluminum Starch Octenylsuccinate can be found in products like foundations, mascaras, lip balms and creams.
Aluminum Starch Octenylsuccinate is a modified starch.
Aluminum Starch Octenylsuccinate is a complex carbohydrate made by plants.
In cosmetics and personal care products, Aluminum Starch Octenylsuccinate is used in the formulation of lotions, powders, makeup and underarm deodorants.
Aluminum Starch Octenylsuccinate is the aluminum salt of the reaction product of octenylsuccinic anhydride with starch.
Aluminum Starch Octenylsuccinate is used in cosmetics at concentrations as high as 30% as an anticaking agent and a nonaqueous viscosity increasing agent.

Uses
Aluminum Starch Octenylsuccinate is a texture enhancer and anti caking agent that also serves other purposes in the world of cosmetics.

Cosmetic products: Aluminum Starch Octenylsuccinate is added to cosmetics because it absorbs excess oil and prevents the product from looking or feeling greasy and tacky.
By improving the texture of the cosmetic formulations, Aluminum Starch Octenylsuccinate enables easy spreadability and allows the makeup to last longer

Skin care: Aluminum Starch Octenylsuccinate is also present in skin care products because of its oil absorbing properties.
Aluminum Starch Octenylsuccinate leaves the skin clean and velvety.

Synonyms:
Starch, hydrogen octenylbutanedioate, aluminum salt
ALUMINIUMSTARCHOCTENYLSUCCINATE
STARCHALUMINIUMOCTENYLSUCCINATE
Aluminum starch octenylbutanedioate
Starch aluminum octenylsuccinate
ALUMINUM STARCH OCTENYLSUCCINATE
starch food modified: starch aluminum octenyl succinate
ALUMINUM TRI POLYPHOSPHATE

Aluminum Tri Polyphosphate, also known as Aluminum Tripolyphosphate or Aluminum Phosphate, is a chemical compound with the formula AlH2P3O10.
Aluminum Tri Polyphosphate is a white, odorless powder that is insoluble in water.
Aluminum Tri Polyphosphate is a type of inorganic phosphate compound that contains aluminum and phosphate ions.

CAS Number: 13939-25-8



APPLICATIONS


Aluminum Tri Polyphosphate is widely used as a flame retardant additive in the production of coatings, paints, plastics, and textiles.
Aluminum Tri Polyphosphate is incorporated into coatings and paints to enhance fire resistance and reduce flammability.
Aluminum Tri Polyphosphate is utilized in the manufacturing of fire-resistant textiles such as curtains, upholstery, carpets, and protective clothing.
Aluminum Tri Polyphosphate helps to improve the fire safety of textiles, making them suitable for applications in high-risk environments.

Aluminum Tri Polyphosphate is employed in the production of fireproof coatings for structural materials in buildings and other infrastructure.
Aluminum Tri Polyphosphate is used as a flame retardant in the manufacturing of plastics, including electronics, automotive components, and household products.
Aluminum Tri Polyphosphate is added to foam insulation materials to enhance their fire resistance and meet safety regulations.

Aluminum Tri Polyphosphate is utilized in the production of fire-resistant cables and wires, ensuring electrical safety.
Aluminum Tri Polyphosphate is used in the formulation of adhesives and sealants to provide fire resistance and improve their performance.
Aluminum Tri Polyphosphate finds applications in the construction industry, where it is used in the production of fire-resistant gypsum boards and composite panels.

Aluminum Tri Polyphosphate is employed as a corrosion inhibitor in metal coatings and primers, preventing metal corrosion and extending the lifespan of coated surfaces.
Aluminum Tri Polyphosphate is utilized in the automotive industry to enhance the fire resistance of interior components, such as dashboards and seat covers.
Aluminum Tri Polyphosphate is used in the production of fire-resistant foams for mattresses and upholstery in the furniture industry.
Aluminum Tri Polyphosphate finds applications in the marine industry, where it is used in coatings and textiles to enhance fire safety on ships and vessels.
Aluminum Tri Polyphosphate is utilized in the aerospace industry to meet stringent fire safety standards for aircraft interiors.

Aluminum Tri Polyphosphate is added to intumescent coatings to enhance their fire resistance and create a protective barrier when exposed to heat.
Aluminum Tri Polyphosphate is used in the formulation of fire-resistant paints for steel structures and industrial equipment.
Aluminum Tri Polyphosphate is employed in the production of fire-resistant curtains and drapes for theaters and public spaces.
Aluminum Tri Polyphosphate finds applications in the production of fire extinguisher powders and formulations.
Aluminum Tri Polyphosphate is used in the manufacturing of fire-resistant wallpapers and wall coverings for commercial and residential buildings.

Aluminum Tri Polyphosphate is utilized in the production of fire-resistant foam seals and gaskets for industrial applications.
Aluminum Tri Polyphosphate is added to fire-resistant concrete formulations to improve their resistance to high temperatures.
ATPP finds applications in the production of fire-resistant panels and partitions for interior spaces.
Aluminum Tri Polyphosphate is used in the formulation of fire-resistant coatings for electrical equipment and appliances.

Aluminum Tri Polyphosphate is employed in the production of fire-resistant textiles for military and firefighting uniforms.
Aluminum Tri Polyphosphate is used in the production of fire-resistant curtains and blinds for commercial and residential spaces.
Aluminum Tri Polyphosphate finds applications in the formulation of fire-resistant varnishes and coatings for wooden surfaces.
Aluminum Tri Polyphosphate is utilized in the production of fire-resistant flexible hoses and tubing for industrial applications.

Aluminum Tri Polyphosphate is added to fire-resistant paints for steel structures, bridges, and pipelines to enhance their resistance to fire.
Aluminum Tri Polyphosphate is employed in the manufacturing of fire-resistant roofing materials, such as shingles and tiles.
Aluminum Tri Polyphosphate finds applications in the production of fire-resistant sealants and caulks for construction and industrial use.
Aluminum Tri Polyphosphate is used in the formulation of fire-resistant mortars and grouts for construction and masonry applications.

Aluminum Tri Polyphosphate is utilized in the production of fire-resistant fabrics for theater curtains, stage backdrops, and event decorations.
Aluminum Tri Polyphosphate is added to fire-resistant adhesives used in the bonding of materials requiring high fire safety standards.
It finds applications in the production of fire-resistant composite materials for aerospace and automotive industries.
Aluminum Tri Polyphosphate is employed in the formulation of fire-resistant coatings for electrical cabinets and control panels.
Aluminum Tri Polyphosphate is used in the manufacturing of fire-resistant insulation materials for HVAC systems and ductwork.

Aluminum Tri Polyphosphate finds applications in the production of fire-resistant partitions and walls for commercial and industrial buildings.
Aluminum Tri Polyphosphate is added to fire-resistant mastics and sealants for air ducts and ventilation systems.
Aluminum Tri Polyphosphate is utilized in the production of fire-resistant foam boards used for insulation and soundproofing.
It finds applications in the formulation of fire-resistant coatings for storage tanks and pipelines in the oil and gas industry.

Aluminum Tri Polyphosphate is used in the production of fire-resistant carpets and flooring materials for public spaces and transportation.
Aluminum Tri Polyphosphate is employed in the manufacturing of fire-resistant composite panels for façade cladding and architectural applications.
Aluminum Tri Polyphosphate is added to fire-resistant mortars and concrete mixes for fire-rated walls and structural elements.
Aluminum Tri Polyphosphate finds applications in the production of fire-resistant electrical enclosures and control cabinets.
Aluminum Tri Polyphosphate is utilized in the formulation of fire-resistant coatings for shipboard applications, including bulkheads and decks.
Aluminum Tri Polyphosphate is used in the manufacturing of fire-resistant glass and glazing systems for buildings and vehicles.

Aluminum Tri Polyphosphate finds applications in the production of fire-resistant air filters for HVAC systems and cleanrooms.
It is added to fire-resistant gels and foams used in firefighting and emergency response applications.
Aluminum Tri Polyphosphate is employed in the formulation of fire-resistant tapes and wraps for cable and wire insulation.


Here are some of its common applications:

Flame Retardants:
Aluminum Tri Polyphosphate is widely used as a flame retardant additive in the production of coatings, paints, plastics, and textiles.
Aluminum Tri Polyphosphate reduces the flammability of these materials and slows down the spread of flames, enhancing fire safety.

Coatings and Paints:
Aluminum Tri Polyphosphate is incorporated into coatings and paints to improve their fire resistance.
Aluminum Tri Polyphosphate helps to create a protective barrier that prevents the spread of fire and the release of toxic fumes.

Textiles:
Aluminum Tri Polyphosphate is utilized in the manufacturing of fire-resistant textiles, such as curtains, upholstery, carpets, and protective clothing.
Aluminum Tri Polyphosphate enhances the fire retardancy of these materials, making them safer in fire-prone environments.

Adhesives and Sealants:
Aluminum Tri Polyphosphate is added to adhesives and sealants to provide fire resistance and improve their overall performance.
Aluminum Tri Polyphosphate helps to increase the fire safety of bonded or sealed surfaces.

Plastics and Polymers:
Aluminum Tri Polyphosphate is used as a flame retardant in the production of various plastic products, including electronics, automotive components, and construction materials.
Aluminum Tri Polyphosphate helps to reduce the flammability of these materials and prevent the rapid spread of fire.

Construction Materials:
Aluminum Tri Polyphosphate is added to construction materials such as insulation foams, gypsum boards, and composite panels to enhance their fire resistance.
Aluminum Tri Polyphosphate contributes to the safety of buildings by slowing down the progression of fire and reducing the release of toxic gases.

Corrosion Inhibition:
Aluminum Tri Polyphosphate is employed as a corrosion inhibitor in metal coatings and primers.
Aluminum Tri Polyphosphate forms a protective layer on the metal surface, preventing corrosion and improving the durability of the coating.

Adhesion Promoters:
Aluminum Tri Polyphosphate is used as an adhesion promoter in various formulations, especially in metal coatings and primers.
Aluminum Tri Polyphosphate enhances the bonding strength between the substrate and the coating, improving adhesion and durability.

Automotive Industry:
Aluminum Tri Polyphosphate finds applications in the automotive industry, where it is used in coatings, plastics, and textiles to meet fire safety regulations.
Aluminum Tri Polyphosphate helps to reduce the flammability of interior components and enhance passenger safety.

Marine and Aerospace Industries:
Aluminum Tri Polyphosphate is utilized in marine and aerospace applications where fire safety is crucial.
Aluminum Tri Polyphosphate is used in coatings, textiles, and plastics to enhance fire resistance and comply with stringent safety standards.



DESCRIPTION


Aluminum Tri Polyphosphate is a white, crystalline powder with a fine particle size.
Aluminum Tri Polyphosphate has a high melting point and is insoluble in water.
Aluminum Tri Polyphosphate has a chemical formula of AlH2P3O10.

Aluminum Tri Polyphosphate is composed of aluminum ions (Al3+) and polyphosphate ions (P3O10^-5).
Aluminum Tri Polyphosphate is odorless, non-toxic, and non-combustible.
Aluminum Tri Polyphosphate is stable under normal conditions of use and storage.
Aluminum Tri Polyphosphate exhibits good thermal stability and does not decompose easily.

Aluminum Tri Polyphosphate is commonly used as a flame retardant in various industries.
Aluminum Tri Polyphosphate acts as a fire-resistant additive by releasing water when exposed to heat, reducing the temperature of the material and slowing down the spread of flames.
Aluminum Tri Polyphosphate forms a protective layer on the surface of materials, preventing combustion and the release of toxic gases.
Aluminum Tri Polyphosphate is effective in improving the fire resistance of coatings, paints, and textiles.

Aluminum Tri Polyphosphate is also used as a corrosion inhibitor, providing protection against metal corrosion.
Aluminum Tri Polyphosphate forms a protective film on the metal surface, inhibiting the corrosive action of moisture, chemicals, and other environmental factors.
Aluminum Tri Polyphosphate is often utilized in the formulation of coatings, primers, and sealants for metal substrates.
Aluminum Tri Polyphosphate is compatible with various resins and binders, facilitating its incorporation into different formulations.

Aluminum Tri Polyphosphate can enhance the adhesion and durability of coatings, improving their resistance to wear and environmental degradation.
Aluminum Tri Polyphosphate is widely employed in the automotive, aerospace, construction, and marine industries.
Aluminum Tri Polyphosphate is used in the production of fireproof textiles, such as curtains, upholstery, and protective clothing.
Aluminum Tri Polyphosphate is known for its high efficiency as a flame retardant, requiring relatively low loading levels to achieve desired fire protection.
Aluminum Tri Polyphosphate is also used in the manufacturing of plastics, foams, and rubber products to enhance their fire resistance.

Aluminum Tri Polyphosphate is compatible with various manufacturing processes, including extrusion, injection molding, and compression molding.
Aluminum Tri Polyphosphate is an environmentally friendly alternative to certain halogenated flame retardants that are known to be harmful to health and the environment.
Aluminum Tri Polyphosphate exhibits low volatility and does not release toxic fumes during combustion.
Aluminum Tri Polyphosphate is regulated and complies with international standards and regulations for fire safety.
Aluminum Tri Polyphosphate is a versatile compound that plays a crucial role in enhancing fire safety and corrosion protection in a wide range of applications.

Aluminum Tri Polyphosphate, also known as Aluminum Tripolyphosphate or Aluminum Phosphate, is a chemical compound with the formula AlH2P3O10.
Aluminum Tri Polyphosphate is a white, odorless powder that is insoluble in water.
Aluminum Tri Polyphosphate is a type of inorganic phosphate compound that contains aluminum and phosphate ions.

Aluminum Tri Polyphosphate is often used as a flame retardant and as a corrosion inhibitor in various applications.
Aluminum Tri Polyphosphate works by forming a protective layer on the surface of materials, inhibiting the spread of flames and preventing the formation of corrosive by-products.
Aluminum Tri Polyphosphate is commonly used in the production of coatings, paints, adhesives, and sealants, as well as in the manufacturing of plastics, textiles, and construction materials.



PROPERTIES


Chemical formula: AlH2P3O10
Molecular weight: Approximately 393.95 g/mol
Appearance: White crystalline powder
Odor: Odorless
Solubility: Insoluble in water
Melting point: Decomposes above 250°C (482°F)
Density: 2.7 g/cm³
pH value: Neutral
Boiling point: Decomposes before boiling
Vapor pressure: Negligible
Flammability: Non-flammable
Stability: Stable under normal conditions of use and storage
Hygroscopicity: Low moisture absorption
Particle size: Fine powder
Refractive index: Not available
Electrical conductivity: Non-conductive
Optical properties: Not applicable
Toxicity: Generally considered non-toxic, but should be handled with care and in accordance with safety guidelines
Environmental impact: Considered environmentally friendly with low ecological impact
Compatibility: Compatible with various resins, binders, and additives



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air and ensure they are in a well-ventilated area.
If breathing is difficult, provide oxygen support if available and seek medical attention immediately.
In case of severe respiratory distress, call emergency services or a poison control center.


Skin Contact:

Remove contaminated clothing and rinse the affected area with plenty of water for at least 15 minutes.
If irritation or redness persists, seek medical advice and provide the medical personnel with detailed information about the exposure.


Eye Contact:

Rinse the eyes with gently flowing water for at least 15 minutes, keeping the eyelids open to ensure thorough irrigation.
Remove contact lenses if present and continue rinsing.
Seek immediate medical attention, providing information about the substance involved in the eye exposure.


Ingestion:

Ingestion of Aluminum Tri Polyphosphate is unlikely to occur, but if swallowed accidentally, do not induce vomiting.
Rinse the mouth with water and drink plenty of water to dilute the substance.
Seek immediate medical attention or contact a poison control center for further guidance.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and protective clothing to minimize direct contact with ATPP.

Ventilation:
Handle ATPP in a well-ventilated area or under local exhaust ventilation to prevent the buildup of airborne dust or fumes.

Avoid Inhalation:
Avoid breathing in the dust or mist generated during handling.
Use respiratory protection (e.g., dust mask or respirator) if necessary.

Avoid Skin and Eye Contact:
Prevent skin contact by wearing suitable protective gloves and clothing. In case of contact, promptly rinse with water.
Wear safety goggles or a face shield to protect the eyes.

Hygiene Practices:
Wash hands and any exposed skin thoroughly after handling ATPP.
Avoid eating, drinking, or smoking in areas where the compound is present.

Spill and Leak Response:
In the event of a spill, contain and collect the material using appropriate absorbent materials.
Avoid generating dust. Dispose of collected material according to local regulations.


Storage:

Store in a Dry Place:
Keep ATPP in a cool, dry, and well-ventilated area away from direct sunlight, heat sources, and incompatible materials.

Temperature:
Maintain storage temperatures within the recommended range specified by the manufacturer.

Moisture Control:
Prevent exposure to moisture or excessive humidity as it may affect the performance and integrity of ATPP.

Containment:
Store ATPP in tightly sealed containers or bags to minimize the risk of dust generation or contamination.

Compatibility:
Keep ATPP away from incompatible substances, including strong acids, strong bases, oxidizing agents, and reactive metals.

Labeling:
Clearly label containers with the name of the substance, hazard symbols, safety precautions, and any other relevant information.

Accessibility:
Store ATPP in a designated area that is inaccessible to unauthorized personnel, children, and pets.

Fire Safety:
Keep ATPP away from potential ignition sources and incompatible materials that may pose a fire hazard.

Follow Regulations:
Adhere to local regulations and guidelines regarding the storage and handling of ATPP.

Inventory Control:
Maintain proper inventory control to ensure FIFO (First In, First Out) usage and prevent long-term storage.



SYNONYMS


Aluminum Tripolyphosphate
Aluminum Polyphosphate
Aluminophosphate
Alumino Tripolyphosphate
Aluminosodium Tripolyphosphate
Aluminum Phosphate
Aluminum Triphosphate
Alumina Phosphate
Aluminic Acid Tripolyphosphate
Aluminum Salt of Tripolyphosphoric Acid
ATPP
APP
ATP
Aluminotripolyphosphate
Alum
Aluminum Tripolyphosphoric Acid
Aluminum Salt of Tripolyphosphate Acid
Aluminum Tripolyphosphate Hydrate
Aluminum Tripolyphosphate Nonahydrate
Alum Triphosphate
Aluminotriphosphate
Aluminum Polyphosphate Hydrate
Aluminum Tripolyphosphate Sodium
Sodium Aluminophosphate
Sodium Aluminum Tripolyphosphate
Aluminum Tripolyphosphoric Acid Salt
Aluminophosphoric Acid Tripolyphosphate
Aluminum Phosphate Tripoly
Aluminotriphosphoric Acid Salt
Aluminum Tripolyphosphate Hydrated
Aluminum Tripolyphosphoric Acid Sodium Salt
Aluminotriphosphoric Acid Salt
Aluminum Tripolyphosphate Nonahydrate
Alumina Tripolyphosphate
Aluminum Tripolyphosphate Tetrahydrate
Aluminum Tripolyphosphate Monohydrate
Aluminum Tripolyphosphate Hydrated Sodium Salt
Aluminotriphosphoric Acid Sodium Salt
Aluminotriphosphoric Acid Hydrate
Aluminum Tripolyphosphate Anhydrous
Aluminum Tripolyphosphate Octahydrate
Aluminum Tripolyphosphate Dodecahydrate
Aluminophosphate Tripoly
Aluminum Tripolyphosphate Sodium Salt Hydrate
Aluminum Tripolyphosphate Pentahydrate
Aluminophosphoric Acid Tripolyphosphate Sodium Salt
Aluminum Polyphosphate Sodium
Aluminum Tripolyphosphate Nonahydrate Sodium Salt
Aluminum Phosphate Tripolyphosphate Sodium Salt
Aluminotriphosphoric Acid Sodium Salt Hydrate
Aluminum Tripolyphosphate Tetrahydrate Sodium Salt
Aluminum Polyphosphate Sodium Salt
Aluminotriphosphoric Acid Nonahydrate
Aluminum Tripolyphosphate Dihydrate
Aluminum Tripolyphosphate Nonahydrate Potassium Salt
Aluminophosphoric Acid Tripolyphosphate Sodium Salt Hydrate
Aluminum Tripolyphosphate Nonahydrate Ammonium Salt
Aluminum Tripolyphosphate Tetrahydrate Ammonium Salt
Aluminum Tripolyphosphate Nonahydrate Calcium Salt
Aluminotriphosphoric Acid Sodium Salt Tetrahydrate
Aluminum Tripolyphosphate Octahydrate Potassium Salt
Aluminum Tripolyphosphate Tetrahydrate Calcium Salt
Aluminum Tripolyphosphate Nonahydrate Magnesium Salt
Aluminum Tripolyphosphate Pentahydrate Sodium Salt
Aluminophosphoric Acid Tripolyphosphate Calcium Salt
Aluminum Tripolyphosphate Nonahydrate Zinc Salt
Aluminum Tripolyphosphate Dodecahydrate Sodium Salt
Aluminum Tripolyphosphate Octahydrate Calcium Salt
Aluminum Tripolyphosphate Tetrahydrate Sodium Salt Dihydrate
Aluminum Tripolyphosphate Nonahydrate Iron Salt
Aluminum Tripolyphosphate Pentahydrate Potassium Salt
Aluminum Tripolyphosphate Nonahydrate Copper Salt
Aluminotriphosphoric Acid Sodium Salt Nonahydrate
Aluminum Tripolyphosphate Octahydrate Sodium Salt
Aluminum Tripolyphosphate Tetrahydrate Potassium Salt
ALUMINUM TRIHYDROXIDE

Aluminum Trihydroxide, also known as Aluminum Hydroxide (Al(OH)3) is a chemical compound that consists of aluminum and hydroxide ions.
Aluminum trihydroxide is a white, odorless, and tasteless powder that is insoluble in water but soluble in acids and alkalis.
Aluminum trihydroxide is often used as a flame retardant and smoke suppressant in various applications such as plastics, rubber, and textiles.

CAS Number: 21645-51-2
EC Number: 244-492-7



APPLICATIONS


Aluminum trihydroxide is used as a flame retardant in polymeric materials, such as plastics, rubber, and coatings.
Aluminum trihydroxide is used in the production of refractory products, such as ceramic tiles, fire bricks, and furnace linings.
Aluminum trihydroxide is used as a raw material for the production of aluminum chemicals, such as aluminum sulfate and aluminum chloride.

Aluminum trihydroxide is used as an antacid to neutralize stomach acid and treat heartburn, acid indigestion, and sour stomach.
Aluminum trihydroxide is used as a filler in the manufacture of paper, paint, and rubber products.

Aluminum trihydroxide is used as a thickener and viscosity enhancer in cosmetic and personal care products, such as lotions, shampoos, and toothpaste.
Aluminum trihydroxide is used as an adsorbent and catalyst support in chemical processes.

Aluminum trihydroxide is used as a polishing agent in the production of glass, metal, and plastic products.
Aluminum trihydroxide is used as an abrasive in toothpaste and as a cleaning agent in industrial and household applications.
Aluminum trihydroxide is used as a component in automotive coatings and as a corrosion inhibitor in metal coatings.

Aluminum trihydroxide is used as a stabilizer in the processing of PVC plastics.
Aluminum trihydroxide is used in the production of catalysts for the manufacture of polyethylene and other polyolefins.

Aluminum trihydroxide is used as a filler in the manufacture of solid surface materials, such as countertops, sinks, and bathtubs.
Aluminum trihydroxide is used as an ingredient in pharmaceutical formulations, such as antiperspirants and topical creams.

Aluminum trihydroxide is used as a pigment and opacifier in the manufacture of ceramics, glass, and paints.
Aluminum trihydroxide is used in the production of alumina, a key ingredient in the manufacture of aluminum metal and ceramics.

Aluminum trihydroxide is used as a flocculant and coagulant in water treatment and wastewater treatment.
Aluminum trihydroxide is used as a catalyst in the production of biodiesel from vegetable oils and animal fats.
Aluminum trihydroxide is used as a filler in electrical insulation materials, such as cable jackets and circuit boards.

Aluminum trihydroxide is used as a component in the manufacture of adhesives, sealants, and caulks.
Aluminum trihydroxide is used as a clarifying agent in the production of fruit juices, wine, and beer.

Aluminum trihydroxide is used in the production of rubber tires and other automotive components.
Aluminum trihydroxide is used as a catalyst in the production of polypropylene and other polyolefins.

Aluminum trihydroxide is used in the production of synthetic zeolites, which are used as catalysts and adsorbents in a variety of applications.
Aluminum trihydroxide is used as an insulating material in the construction of buildings, such as fireproof doors and windows, and as a component in acoustic insulation materials.


Aluminum Trihydroxide has a wide range of applications in various industries.
Here are some of its common applications:

Flame retardant:
Aluminum Trihydroxide is an effective flame retardant and is widely used in the production of plastic, rubber, and textile products.
Aluminum trihydroxide can help to reduce the risk of fires by suppressing flames and slowing down the combustion process.

Filler:
Aluminum Trihydroxide is often used as a filler in various materials to improve their mechanical properties.
Aluminum trihydroxide can help to increase the stiffness, strength, and hardness of materials, as well as reduce shrinkage and warping.

Antacid:
Aluminum Trihydroxide can be used as an antacid to neutralize excess stomach acid.
Aluminum trihydroxide can help to relieve symptoms of heartburn, acid reflux, and indigestion.

Pigment:
Aluminum Trihydroxide is used as a white pigment in the paper industry.
Aluminum trihydroxide can help to improve the opacity and brightness of paper products.

Raw material:
Aluminum Trihydroxide is a common raw material in the production of aluminum and other metal products.
Aluminum trihydroxide can help to purify metal ores and remove impurities.

Adsorbent:
Aluminum Trihydroxide has a high surface area and can be used as an adsorbent in various applications.
Aluminum trihydroxide can help to remove impurities and pollutants from water, air, and other liquids.

Opacifying agent:
Aluminum Trihydroxide can be used as an opacifying agent in transparent materials such as plastics and paints.
Aluminum trihydroxide can help to reduce transparency and increase opacity.

Insulating material:
Aluminum Trihydroxide has low electrical conductivity and can be used as an insulating material.
Aluminum trihydroxide can help to prevent the flow of electricity and reduce the risk of electrical fires.

Precision components:
Aluminum Trihydroxide has a low coefficient of thermal expansion and can be used in the production of precision components.
Aluminum trihydroxide can help to reduce distortion and improve dimensional accuracy.

Heat sink:
Aluminum Trihydroxide has good thermal conductivity and can be used as a heat sink.
Aluminum trihydroxide can help to dissipate heat and prevent overheating in electronic devices.

UV stabilizer:
Aluminum Trihydroxide is resistant to UV radiation and can be used as a UV stabilizer.
Aluminum trihydroxide can help to protect materials from damage caused by exposure to sunlight.

Abrasive:
Aluminum Trihydroxide has low abrasiveness and can be used as a gentle exfoliant in personal care products.
Aluminum trihydroxide can help to remove dead skin cells and improve skin texture.

Scratch resistance:
Aluminum Trihydroxide is often used as a filler in paints and coatings to improve their scratch resistance.
Aluminum trihydroxide can help to protect surfaces from damage caused by abrasion and wear.

Environmental safety:
Aluminum Trihydroxide is an environmentally friendly alternative to other flame retardant materials, as it does not release harmful gases when exposed to fire.
Aluminum trihydroxide is also non-toxic and considered to be safe for most applications.

Ceramic production:
Aluminum Trihydroxide is a common raw material in the production of ceramics.
Aluminum trihydroxide can help to improve the strength, durability, and stability of ceramic products.

Coagulant:
Aluminum Trihydroxide can be used as a coagulant in water treatment to help remove impurities and clarify water.

Adhesive:
Aluminum Trihydroxide can be used as a filler in adhesives to improve their bonding strength and increase their resistance to water and chemicals.

Soundproofing:
Aluminum Trihydroxide can be used as a filler in soundproofing materials to improve their acoustic properties.

Insulator:
Aluminum Trihydroxide can be used as an insulator in the production of electrical wires and cables. It can help to prevent the flow of electricity and reduce the risk of electrical fires.

Food additive:
Aluminum Trihydroxide is an approved food additive that can be used as a color retention agent, pH control agent, and anti-caking agent.

Rubber production:
Aluminum Trihydroxide can be used as a filler in rubber products to improve their mechanical properties and increase their resistance to heat and chemicals.

Textile production:
Aluminum Trihydroxide can be used as a flame retardant in textile production to improve the fire resistance of fabrics.

Cosmetics: Aluminum
Trihydroxide can be used as an opacifying agent in cosmetics such as foundations and sunscreens.

Pharmaceuticals:
Aluminum Trihydroxide can be used as an antacid in pharmaceutical products such as tablets and suspensions.

Packaging materials:
Aluminum Trihydroxide can be used as a filler in packaging materials such as plastic films and containers to improve their mechanical properties and reduce their environmental impact.

Flame retardant:
Aluminum Trihydroxide is a common flame retardant used in plastics, textiles, and other materials to reduce the risk of fire.

Building materials:
Aluminum Trihydroxide can be used in building materials such as concrete, insulation, and roofing to improve their fire resistance.

Paints and coatings:
Aluminum Trihydroxide can be used as a filler in paints and coatings to improve their fire resistance and reduce their flammability.

Ceramic production:
Aluminum Trihydroxide can be used in the production of ceramics to improve their mechanical properties and increase their resistance to heat and chemicals.

Glass production:
Aluminum Trihydroxide can be used as a flux in glass production to reduce the melting temperature and improve the flow properties of the glass.

Polymer production:
Aluminum Trihydroxide can be used as a filler in polymer production to improve their mechanical properties and reduce their flammability.

Paper production:
Aluminum Trihydroxide can be used in paper production as a filler to improve the opacity, brightness, and printability of the paper.

Pigment production:
Aluminum Trihydroxide can be used as a pigment in the production of white and colored paints, coatings, and plastics.

Water treatment:
Aluminum Trihydroxide can be used as a coagulant in water treatment to remove impurities and clarify water.

Adhesives:
Aluminum Trihydroxide can be used as a filler in adhesives to improve their bonding strength and increase their resistance to water and chemicals.

Soundproofing:
Aluminum Trihydroxide can be used as a filler in soundproofing materials to improve their acoustic properties.

Insulators:
Aluminum Trihydroxide can be used as an insulator in the production of electrical wires and cables to prevent the flow of electricity and reduce the risk of electrical fires.

Food additive:
Aluminum Trihydroxide is an approved food additive that can be used as a color retention agent, pH control agent, and anti-caking agent.

Rubber production:
Aluminum Trihydroxide can be used as a filler in rubber products to improve their mechanical properties and increase their resistance to heat and chemicals.

Textile production:
Aluminum Trihydroxide can be used as a flame retardant in textile production to improve the fire resistance of fabrics.

Cosmetics:
Aluminum Trihydroxide can be used as an opacifying agent in cosmetics such as foundations and sunscreens.

Pharmaceuticals:
Aluminum Trihydroxide can be used as an antacid in pharmaceutical products such as tablets and suspensions.

Packaging materials:
Aluminum Trihydroxide can be used as a filler in packaging materials such as plastic films and containers to improve their mechanical properties and reduce their environmental impact.

Abrasives:
Aluminum Trihydroxide can be used as an abrasive in the production of grinding wheels, sandpaper, and other abrasive materials.

Welding rods:
Aluminum Trihydroxide can be used as a filler in welding rods to improve their mechanical properties and increase their resistance to heat and chemicals.

Lubricants:
Aluminum Trihydroxide can be used as a lubricant in metalworking and other industrial applications to reduce friction and wear.

Catalysts:
Aluminum Trihydroxide can be used as a catalyst in chemical reactions to speed up the reaction rate and improve the yield of the desired product.

Emulsifiers:
Aluminum Trihydroxide can be used as an emulsifier in food and cosmetic products to improve the texture and stability of the product.



DESCRIPTION


Aluminum Trihydroxide, also known as Aluminum Hydroxide (Al(OH)3) is a chemical compound that consists of aluminum and hydroxide ions.
Aluminum trihydroxide is a white, odorless, and tasteless powder that is insoluble in water but soluble in acids and alkalis.
Aluminum trihydroxide is often used as a flame retardant and smoke suppressant in various applications such as plastics, rubber, and textiles.

In addition to its use as a flame retardant, Aluminum Trihydroxide is also used as an antacid to relieve symptoms of heartburn and stomach upset.
Aluminum trihydroxide works by neutralizing excess stomach acid, which can help to reduce the irritation and discomfort caused by acid reflux and other gastrointestinal conditions.

Aluminum Trihydroxide has also been used as a filler in various materials to improve their mechanical properties.
For example, it is commonly added to polymer composites to increase their strength, stiffness, and durability.

Other applications of Aluminum Trihydroxide include its use as a raw material for the production of aluminum and as a component in ceramic glazes.
Aluminum trihydroxide is also used in the paper industry as a filler and coating pigment to improve the brightness and opacity of paper products.

Aluminum Trihydroxide is considered to be relatively safe and non-toxic, with low levels of acute toxicity and no evidence of carcinogenicity.
However, prolonged exposure to high levels of aluminum can cause respiratory problems and neurological disorders, so appropriate precautions should be taken when handling and using this compound.

Aluminum Trihydroxide is a white, crystalline powder with a high degree of purity.
Aluminum trihydroxide has a molecular weight of 78 g/mol and a density of 2.42 g/cm³.

Aluminum trihydroxide has a melting point of approximately 300°C and is insoluble in water.
Aluminum Trihydroxide is highly stable, non-flammable, and non-toxic.
Aluminum trihydroxide is often used as a flame retardant and smoke suppressant in various applications.

Aluminum trihydroxide has good thermal stability and can withstand high temperatures.
Aluminum Trihydroxide is an effective antacid that can neutralize excess stomach acid.

Aluminum trihydroxide is commonly used in the production of aluminum and other metal products.
Aluminum trihydroxide is often added to plastic, rubber, and textile products to improve their flame retardant properties.

Aluminum Trihydroxide is also used as a filler in various materials to improve their mechanical properties.
Aluminum trihydroxide is commonly used as a raw material in the production of ceramics.

Aluminum Trihydroxide has a high surface area, which makes it useful as an adsorbent in various applications.
Aluminum trihydroxide has a low refractive index and can be used as a filler in transparent materials.
Aluminum Trihydroxide is highly stable in acidic and alkaline environments.

Aluminum trihydroxide has good dispersibility and can be easily incorporated into various products.
Aluminum trihydroxide is often used as a pigment and opacifying agent in the paper industry.

Aluminum Trihydroxide has low electrical conductivity and can be used as an insulating material.
Aluminum trihydroxide is compatible with a wide range of polymers and resins.

Aluminum trihydroxide has low abrasiveness and can be used as a gentle exfoliant in personal care products.
Aluminum Trihydroxide is resistant to UV radiation and can be used as a UV stabilizer.
Aluminum trihydroxide has low toxicity and is considered to be safe for most applications.

Aluminum Trihydroxide has a low coefficient of thermal expansion, which makes it useful in the production of precision components.
Aluminum trihydroxide has good thermal conductivity and can be used as a heat sink.

Aluminum trihydroxide is often used as a filler in paints and coatings to improve their durability and scratch resistance.
Aluminum Trihydroxide is an environmentally friendly alternative to other flame retardant materials, as it does not release harmful gases when exposed to fire.



PROPERTIES


Chemical formula: Al(OH)3
Molecular weight: 78.0 g/mol
Appearance: White powder
Density: 2.42 g/cm³
Melting point: 300°C (572°F)
Boiling point: Decomposes before boiling
Solubility: Insoluble in water and organic solvents
pH: 9.5 to 10.5 (in a 10% aqueous suspension)
Refractive index: 1.57 to 1.59
Mohs hardness: 2.5 to 3.5
Heat capacity: 0.8 J/g·K
Thermal conductivity: 0.3 W/m·K
Specific heat: 1.17 J/g·K
Electrical conductivity: 1.6 x 10^-7 S/cm
Dielectric constant: 5.6
Optical properties: Aluminum trihydroxide is a white, opaque material that does not transmit light.
Flame retardancy: Aluminum trihydroxide decomposes at high temperatures to release water vapor, which cools the surrounding area and dilutes the concentration of flammable gases. This mechanism helps to slow or stop the spread of flames in plastic materials.
Stability: Aluminum trihydroxide is stable under normal conditions but can decompose at high temperatures to release water vapor and aluminum oxide.
Toxicity: Aluminum trihydroxide is not considered toxic but can cause irritation to the eyes, skin, and respiratory system upon exposure.



FIRST AID


Handling:

Avoid contact with skin, eyes, and clothing. Wear appropriate protective equipment such as gloves, safety goggles, and a respirator when handling aluminum trihydroxide.
Use caution when handling large quantities of aluminum trihydroxide, as the powder can become airborne and potentially cause respiratory irritation.

Handle aluminum trihydroxide in a well-ventilated area to prevent the buildup of dust and fumes.
Do not ingest aluminum trihydroxide or allow it to come into contact with food or beverages.
Avoid generating dust when handling aluminum trihydroxide, as the dust can be a respiratory hazard.


Storage:

Store aluminum trihydroxide in a cool, dry, well-ventilated area away from sources of heat and ignition.
Store aluminum trihydroxide in airtight containers to prevent contamination and moisture uptake.
Do not store aluminum trihydroxide near acids or other incompatible materials that could cause a reaction.

Keep aluminum trihydroxide away from direct sunlight and other sources of UV radiation, as this can cause degradation and discoloration.
Store aluminum trihydroxide separately from food and pharmaceutical products to prevent contamination.
Follow all local, state, and federal regulations regarding the storage, handling, and disposal of aluminum trihydroxide.



HANDLING AND STORAGE


Inhalation:

If aluminum trihydroxide is inhaled, move the affected person to an area with fresh air immediately.
If the person is having difficulty breathing, seek medical attention right away.
If the person is not breathing, administer CPR and seek medical attention immediately.


Skin Contact:

If aluminum trihydroxide comes into contact with the skin, immediately remove any contaminated clothing and wash the affected area with soap and water.
If irritation or redness occurs, seek medical attention.


Eye Contact:

If aluminum trihydroxide comes into contact with the eyes, immediately flush the eyes with water for at least 15 minutes, lifting the upper and lower eyelids occasionally.
Seek medical attention if irritation or redness persists.


Ingestion:

If aluminum trihydroxide is ingested, do not induce vomiting unless instructed to do so by a medical professional.
Give the affected person water to drink and seek medical attention immediately.
If the person is unconscious or having difficulty breathing, call emergency services right away.


Other Measures:

Seek medical attention if symptoms such as coughing, wheezing, or shortness of breath occur after exposure to aluminum trihydroxide.
If the affected person is a first responder or healthcare worker, follow established protocols for decontamination and seek medical attention immediately.
Provide the medical professional with the product's safety data sheet (SDS) for proper treatment.



SYNONYMS


Aluminum hydroxide
Aluminum hydrate
Aluminum(III) hydroxide
Aluminum trihydrate
ATH
Alumina trihydrate
Aluminic acid trihydrate
C.I. 77002
Dihydroxyaluminum sodium carbonate
Gibbsite
Hydrated alumina
Hydrated aluminum oxide
Trihydroxyaluminum
Aluminic hydroxide
Aluminous hydroxide
Alhydrogel
Alugel
Aluminium hydrate oxide
Aluminium hydroxide gel
Aluminum(III) oxide trihydrate
Aluminum trioxohydroxide
Hydrargillite
Pural SB
Sipernat D 10
Vistalon 5003
Alcoa Hydrate
Albacar HOV
Alcoa C-31
Alcoa T-20
Aloca V-31
Alhydrogel 1
Aluminic acid, trihydrate
Aluminic hydroxide, trihydrate
Aluminium hydroxide, trihydrate
Aluminum oxide, trihydrate
Aluminum trioxohydroxide, trihydrate
Aluminous hydroxide, trihydrate
Dihydroxyaluminum carbonate
Dihydroxyaluminum sodium carbonate hydrate
Flame-retardant ATH
Gibbsite hydrate
Hidrox 150
Hydral
Hydrocal HG
Hydral D710
Hydral T710
Hydragil
KB 30
Martinal ON 310
P-30.
ALUMINYUM STEARAT TIPLERI (MONO,DI,TRI)
Aluminum chlorhydrol; Aluminum chlorohydrate; Aluminum hydroxide chloride; Aluminum hydroxychloride; Aluminum hydroxychloride dihydrate CAS NO:1327-41-9
Aluminium Sulfate
Alum; Aluminium sulphate; Aluminum Alum; Aluminum sulfate anhydrous; Aluminum trisulfate anhydrous; Cake Alum; Dialuminum sulfate; Sulfuric acid aluminum salt (3:2); Aluminiumsulfat (German); Sulfato de aluminio (Spanish); Sulfate d'aluminium (French); Aluminum sesquisulfate CAS NO:10043-01-3
Aluminum Chlorohydrate
SynonymsAPP 201;Aluminum chlorohydra;Aluminum oxychloride;ALUMINIUMCHLORHYDRATE;aluminiumchlorohydrate;ALUMINUM CHLOROHYDRATE;ALUMINIUM POLYCHLORIDE;Aluminum hydroxychloride;Aluminiumhydroxychlorid8;Spray pressurefilter PAC CAS No.1327-41-9
Aluminum Hydroxide Trihydrate
cas no: 629-11-8 Hexamethylene Glycol; Hexamethylenediol; HDO; 1,6-Dihydroxyhexane; omega-Hexanediol; alpha,omega-Hexanediol; Hexane-1,6-diol; alpha,omega-Hexanediol; 6-hydroxy-1-hexanol;
Aluminum Sulfate
SYNONYMS Alum; Aluminium sulphate; Aluminum Alum; Aluminum sulfate anhydrous; Aluminum trisulfate anhydrous; Cake Alum; Dialuminum sulfate; Sulfuric acid aluminum salt (3:2); Aluminiumsulfat (German); Sulfato de aluminio (Spanish); Sulfate d'aluminium (French); Aluminum sesquisulfate; Other RN: 10124-29-5, 121739-79-5, 124027-27-6, 139939-73-4, 19239-71-5, 22515-37-3, 66578-72-1, 17927-65-0 CAS NO. 10043-01-3
AMERICAN GINSENG ROOT EXTRACT
American Ginseng Root Extract reduces the risk of cancer.
American Ginseng Root Extract improves mental performance and well being.


INCI Name: Panax Quinquefolius Root Extract
Botanical Name: Panax quinquefolius
Main Active Components: Ginsenosides (similar to other types of ginseng)



SYNONYMS:
Anchi Ginseng, Baie Rouge, Canadian Ginseng, Ginseng, Ginseng à Cinq Folioles, Ginseng Américain, Ginseng Americano, Ginseng d'Amérique, Ginseng D'Amérique du Nord, Ginseng Canadien, Ginseng de l'Ontario, Ginseng du Wisconsin, Ginseng Occidental, Ginseng Root, North American Ginseng, Occidental Ginseng, Ontario Ginseng, Panax Quinquefolia, Panax Quinquefolium, Panax quinquefolius, Racine de Ginseng, Red Berry, Ren Shen, Sang, Shang, Shi Yang Seng, Wisconsin Ginseng, Xi Yang Shen, Aralia quinquefolia (L.) Decne. & Planch, Ginseng quinquefolium (L.) Alph.Wood, Panax americanus (Raf.) Raf., Panax americanus var. elatus Raf., Panax americanus var. obovatus (Raf.) Raf., Panax cuneatus Raf., Panax quinquefolius var. americanus Raf., Panax quinquefolius var. obovatus Raf, Baie Rouge, Canadian ginseng, Panax quinquefolius, red berry,



American Ginseng Root Extract helps boost the immune system.
American Ginseng Root Extract reduces the risk of cancer.
American Ginseng Root Extract improves mental performance and well being.


American Ginseng Root Extract may be beneficial in the treatment of fatigue, poor memory, diabetes, and viral respiratory infections like colds and flu.
There are many varieties of Ginseng, but the most popular are American ginseng (Panax quinquefolius) and Asian ginseng (Panax ginseng).
American and Asian ginseng vary in their concentration of active compounds and effects on the body.


According to some older research, it is believed that American Ginseng Root Extract works as a relaxing agent, whereas the Asian variety has an invigorating effect
The name "ginseng" is used to refer to both American (Panax quinquefolius) and Asian or Korean ginseng (Panax ginseng), which belong to the genus Panax and have a somewhat similar chemical makeup.


Both Asian and American Ginseng Root Extracts contain ginsenosides, which are the substances thought to give ginseng its medicinal properties.
But they contain different types in different amounts.
Siberian ginseng, or Eleuthero (Eleutherococcus senticosus), is an entirely different plant with different effects.


It is distantly related to ginseng, but it does not contain the same active ingredients.
Like Asian ginseng, American Ginseng Root Extract is a light tan, gnarled root that often looks like a human body with stringy shoots for arms and legs.
Native Americans used the root as a stimulant and to treat headaches, fever, indigestion, and infertility.


Ginseng remains one of the most popular herbs in the United States.
Other studies show that American Ginseng Root Extract might have therapeutic potential for inflammatory diseases.
Research on American Ginseng Root Extract has focused on a number of conditions, including the following.


American Ginseng Root Extract (Panax quinquefolis) is an herb that grows mainly in North America.
Wild American Ginseng Root Extract is in such high demand that it has been declared a threatened or endangered species in some states in the United States.
Don't confuse American Ginseng Root Extract with Siberian ginseng (Eleutherococcus senticosus) or Asian ginseng (Panax ginseng).


They have different medicinal effects.
American Ginseng Root Extract is a high-quality extract powder derived from the root of the American Panax Quinquefolium plant.
American Ginseng Root Extract is a very fine, brown concentrate with a bittersweet flavour and aroma, typical of ginseng, and is the highest quality ginseng root.


American Ginseng (Panax quinquefolius) is a species of flowering plant in the ivy family Araliaceae.
American Ginseng is native to eastern North America and introduced in China.
The specific epithet quinquefolius means "five-leaved", which refers to the typical number of leaflets per leaf.


It is one of a group of taxa known as "ginseng".
Europeans first became aware of American ginseng near Montreal in 1716.
It has been wild-harvested and exported to Asia since 1720.


Billions of plants were wild-harvested in the 19th century alone.
To control international trade and prevent global extinction of the species, the United States Fish and Wildlife Service implements a CITES Export Program that authorizes 19 states and one tribe to export American ginseng from the United States.


From 1978 to 2019, the bulk of exports have come from southern Appalachian states, especially Kentucky, West Virginia, and Tennessee.
The conservation status of American ginseng is globally vulnerable.
It is imperiled or critically imperiled in 14 states and provinces.


In Canada, the species is endangered and facing imminent extinction.
As wild populations declined in the late 19th century, American ginseng became a domesticated crop.
It is cultivated primarily in Ontario, Wisconsin, British Columbia, and China.


Canada is the largest producer and exporter of cultivated American ginseng in the world.
It is the state herb of Wisconsin.
American Ginseng Root Extract (Panax quinquefolius) is an herb that grows mainly in North America.


American Ginseng Root Extract's an endangered species in some states due to high demand.
American Ginseng Root Extract is considered an adaptogen.
Adaptogens are a class of substances that are believed to stimulate the body's resistance to physical, environmental, and emotional stressors.


American Ginseng Root Extract also contains chemicals called ginsenosides, which seem to affect insulin levels and lower blood sugar.
People take American Ginseng Root Extract for stress, to boost the immune system, for upper airway infections, diabetes, and many other conditions, but there is no good scientific evidence to support most of these uses.


Don't confuse American Ginseng Root Extract with Asian ginseng (Panax ginseng) or Eleuthero (Eleutherococcus senticosus).
These are different plants with different effects.
American Ginseng Root Extract (Panax quinquefolius) is an herb that grows mainly in North America.


American Ginseng Root Extract's an endangered species in some states due to high demand.
American Ginseng Root Extract is considered an adaptogen.
Adaptogens are a class of substances that are believed to stimulate the body's resistance to physical, environmental, and emotional stressors.


American Ginseng Root Extract also contains chemicals called ginsenosides, which seem to affect insulin levels and lower blood sugar.
People take American Ginseng Root Extract for stress, to boost the immune system, for upper airway infections, diabetes, and many other conditions, but there is no good scientific evidence to support most of these uses.


Don't confuse American Ginseng Root Extract with Asian ginseng (Panax ginseng) or Eleuthero (Eleutherococcus senticosus).
These are different plants with different effects.
American Ginseng Root Extract (Panax quinquefolius) is a medicinal herb with antioxidant benefits that protect against cell damage and inflammation.


American Ginseng Root Extract (Panax quinquefolium L.) is a source of bioactive phytochemicals with pro-health properties.
Supplements containing American Ginseng Root Extract may improve fatigue, boost memory, and reduce the duration of colds and flu, but more research is needed to confirm its benefits.


American Ginseng Root Extract is considered an adaptogen, which some believe can help the body overcome physical, emotional, and environmental stress.
American Ginseng Root Extract also contains chemicals called ginsenosides, which may help to lower blood sugar.



USES and APPLICATIONS of AMERICAN GINSENG ROOT EXTRACT:
Attention deficit hyperactivity disorder (ADHD) uses of American Ginseng Root Extract: One preliminary study suggests that American Ginseng Root Extract, in combination with ginkgo (Ginkgo biloba), may help treat ADHD.
People take American Ginseng Root Extract by mouth for stress, to boost the immune system, and as a stimulant.


American Ginseng Root Extract is often used to fight infections such as colds and flu.
There is some evidence that American Ginseng Root Extract might help prevent colds and flu and make symptoms milder when infections do occur.
American Ginseng Root Extract is used for other infections including HIV/AIDS, infections of the intestine (dysentery), and particular infections (Pseudomonas infections) that are common in people with cystic fibrosis.


Some people use American Ginseng Root Extract to improve digestion and for loss of appetite, as well as for vomiting, inflammation of the colon (colitis), and inflammation of the lining of the stomach (gastritis).


American Ginseng Root Extract is also used for low iron in the blood (anemia), diabetes, insulin resistance related to HIV treatments, cancer-related fatigue, high blood pressure, trouble sleeping (insomnia), nerve pain, erectile dysfunction (ED), fever, hangover symptoms, attention deficit-hyperactivity disorder (ADHD), blood and bleeding disorders, breast cancer, dizziness, headaches, convulsions, fibromyalgia, "hardening of the arteries" (atherosclerosis), memory loss, rheumatoid arthritis, schizophrenia, improving athletic performance, improving mental performance, as an anti-aging aid, menopausal symptoms, complications during pregnancy or childbirth, and for nervous exhaustion (neurasthenia).


You may also see American Ginseng Root Extract listed as an ingredient in some soft drinks.
Oils and extracts made from American Ginseng Root Extract are used in soaps and cosmetics.
American Ginseng Root Extract is used as a nutritional supplement, in order to support neuro-physical and organ health.


-Immune system enhancement use of American Ginseng Root Extract:
Some scientists believe American Ginseng Root Extract enhances the immune system.
In theory, this improvement in immune function could help the body fight off infection and disease.
Several clinical studies have shown that American Ginseng Root Extract does boost the performance of cells that play a role in immunity.


-Diabetes uses of American Ginseng Root Extract:
Several human studies show that American Ginseng Root Extract lowered blood sugar levels in people with type 2 diabetes.
The effect was seen both on fasting blood sugar and on postprandial (after eating) glucose levels.

One study found that people with type 2 diabetes who took American Ginseng Root Extract before or together with a high-sugar drink experienced less of an increase in blood glucose levels.
Other studies suggest that North American Ginseng Root Extract prevents diabetes-related complications including retinal and cardiac functional changes by reducing stress.


-Cancer uses of American Ginseng Root Extract:
American Ginseng Root Extract has been shown to inhibit tumor growth.
In one laboratory study on colorectal cancer cells, researchers found that American Ginseng Root Extract possessed powerful anti-cancer properties.


-Uses of American Ginseng Root Extract:
Ginseng has been a part of traditional Chinese medicine for over 2,000 years.
In Asia, American Ginseng Root Extract is highly valued for its cooling and sedative medicinal effects (yin), whereas Asian ginseng embodies the warmer aspects of yang.

American Ginseng Root Extract was of minor importance in traditional Native American medicine.
A number of the uses cited in the literature were likely adopted from the Chinese after the export trade from Canada to China began in 1720.
The Iroquois ingested or smoked the roots as a panacea.

The Menominee in northern Wisconsin used American Ginseng Root Extract as a tonic and to increase one's mental capability, while the Penobscot in Maine used it to promote fertility.
The Seminole in Florida used American Ginseng Root Extract for gunshot wounds.

Native peoples from multiple tribes gathered the roots to barter with white traders.
In the late 19th century, the Cherokee sold large quantities of ginseng to traders for fifty cents a pound.
According to James Mooney, a decoction made from its roots was drunk to relieve headaches and cramps.


-Schizophrenia uses of American Ginseng Root Extract:
Early research shows that American Ginseng Root Extract might improve some mental symptoms associated with schizophrenia.
Taking 100 mg of a specific American Ginseng Root Extract called HT1001 (Afexa Life Sciences, Canada) twice daily for 4 weeks improves the patient's ability to hold visual information in the mind short-term. This treatment might also reduce some physical side effects of antipsychotic drugs.
However, American Ginseng Root Extract does not improve other mental symptoms.


-Diabetes uses of American Ginseng Root Extract:
Taking 3 grams of American Ginseng Root Extract by mouth, up to two hours before a meal, can lower blood sugar after a meal in patients with type 2 diabetes.

However, larger doses do not seem to have a greater effect.
Taking 100-200 mg of American Ginseng Root Extract by mouth for 8 weeks might also help lower pre-meal blood sugar levels in patients with type 2 diabetes.
Different American Ginseng Root Extract products may have different effects.
Researchers think that is because they contain different amounts of the active chemicals called ginsenosides.


-Respiratory tract infections uses of American Ginseng Root Extract:
Some research suggests that taking a specific American Ginseng Root Extract called CVT-E002 (Cold-FX, Afexa Life Sciences, Canada) 200-400 mg twice daily for 3-6 months during flu season might prevent cold or flu symptoms in adults between the ages of 18 and 65.
People older than 65 seem to need a flu shot at month 2 along with this treatment in order to decrease their risk of getting the flu or colds.

American Ginseng Root Extract also seems to help make symptoms milder and last a shorter length of time when infections do occur.
Some evidence suggests that American Ginseng Root Extract might not reduce the chance of getting the first cold of a season, but it seems to reduce the risk of getting repeat colds in a season.
However, American Ginseng Root Extract might not help prevent cold or flu-like symptoms in patients with weakened immune systems.


-Fatigue uses of American Ginseng Root Extract:
A 2018 review of four studies suggests that American Ginseng Root Extract may help relieve fatigue caused by chronic illnesses ranging from chronic fatigue syndrome (CFS) to cancer.
The most significant benefit was seen in people who took 2,000 milligrams (mg) daily for eight weeks.

Similar results were seen in a 2019 review examining the effects of American Ginseng Root Extract on people with cancer-related fatigue.
The benefit was greatest in people undergoing active treatment, like chemotherapy or radiation.
As an added bonus, American Ginseng Root Extract does not interact with commonly prescribed chemotherapy drugs like tamoxifen, doxorubicin, methotrexate, or fluorouracil.


-Memory uses of American Ginseng Root Extract:
Limited evidence suggests that American Ginseng Root Extract may improve cognitive function in some people.
This includes the ability to learn, think, reason, and remember.

A 2015 study reported that healthy adults who received a single 200 mg dose of an American Ginseng Root Extract extract (called Cereboost) had increased working memory, peaking within three hours of the dose.

The findings were limited by the small size of the study (52 adults) and the lack of a control group (meaning a group given a sham placebo).
A 2022 study involving 61 adults showed longer-lasting improvements in working memory after taking 200 mg of Cereboost daily for two weeks.

For this study, a control group was included, but the findings were limited by the fact that the research was funded by the manufacturer, Naturex SA.
An unrelated study published in 2012 reported that an American Ginseng Root Extract extract taken twice daily for four weeks improved the working memory of 32 people with schizophrenia compared to a matched set of adults given a placebo.



HOW DOES AMERICAN GINSENG ROOT EXTRACT WORK?
American Ginseng Root Extract contains chemicals called ginsenosides that seem to affect insulin levels in the body and lower blood sugar.
Other chemicals, called polysaccharides, might affect the immune system.



PLANT DESCRIPTION OF AMERICAN GINSENG ROOT EXTRACT:
The American ginseng plant has leaves that grow in a circle around a straight stem.
Yellowish-green, umbrella-shaped flowers grow in the center and produce red berries.
Wrinkles around the neck of the root tell how old the plant is.

This is important because American ginseng is not ready for use until it has grown for about 6 years.
American ginseng is endangered in the wild.
So it tends to be expensive.
It is now being grown on farms to protect wild American ginseng from over-harvesting.



WHAT IS AMERICAN GINSENG ROOT EXTRACT MADE OF?
American Ginseng Root Extract products are made from ginseng root and the long, thin offshoots called root hairs.
The main chemical ingredients of American Ginseng Root Extract are ginsenosides and polysaccharide glycans (quinquefolans A, B, and C).
American Ginseng Root Extract seems to be more relaxing than Asian ginseng, which may have stimulating effects.



AVAILABLE FORMS OF AMERICAN GINSENG ROOT EXTRACT:
American Ginseng Root Extract is available in water, water and alcohol, alcohol liquid extracts, and in powders, capsules, and tablets.
American Ginseng Root Extract is available with other herbs in several combination formulas.

Be sure to read the label carefully so that you are purchasing the type of ginseng that you want.
If you are looking for Asian ginseng, make sure you buy Korean, red, or Panax ginseng.
If you are looking for American Ginseng Root Extract, you should buy Panax quinquefolius.

Eleuthero (Eleutherococcus senticosus), which is sometimes called Siberian ginseng, may also be found in health food stores or pharmacies.
It does not have the same active ingredients as Asian or American Ginseng Root Extract.

Both American Ginseng Root Extract (Panax quinquefolius, L.) and Asian ginseng (P. Ginseng) may boost energy, lower blood sugar, and cholesterol levels, reduce stress, promote relaxation, treat diabetes, and manage sexual dysfunction in men.



IS AMERICAN GINSENG ROOT EXTRACT SAFE?
When taken by mouth: American Ginseng Root Extract is likely safe when used short-term.
Doses of 100-3000 mg daily have been used safely for up to 12 weeks.
Side effects might include headache, but American Ginseng Root Extract's usually well-tolerated.



TYPES OF AMERICAN GINSENG ROOT EXTRACT:
American Ginseng Root Extract is a distinctive type of ginseng used in traditional Chinese medicine.
American Ginseng Root Extract and Asian ginseng (Panax ginseng) are both considered true ginseng in that they contain an organic chemical called ginsenoside.

Even so, American Ginseng Root Extract has a different chemical makeup and "cooler" yin qualities than Asian ginseng.
American Ginseng Root Extract is also less stimulating.
Because of this, American Ginseng Root Extract is widely exported to Asia where it is highly valued for its cooling and sedative effects.

Siberian ginseng (Eleutherococcus senticosus) is not a true ginseng, It is a small, woody shrub with blackberry-like fruit found in northeastern Asia.
While it is also used in traditional Chinese medicine, neither the berries, leaves, stalks, nor roots contain ginsenoside.



BENEFITS OF AMERICAN GINSENG ROOT EXTRACT:
There are two main types of American Ginseng Root Extract: Asian or Korean Ginseng (Panax Ginseng) and American Ginseng Root Extract (Panax quinquefolius).
Studies show that different types have different benefits.
In traditional Chinese medicine, American Ginseng Root Extract is considered less stimulating than the Asian variety.

Although many other herbs are called American Ginseng Root Extract—like Eleuthero or Siberian Ginseng Root Extract—they don't contain the active ingredient of ginsenosides.

American Ginseng Root Extract has traditionally been used for a number of medical conditions.
But American Ginseng Root Extract's benefits for most of them haven't been seriously researched.
Anecdotally, the root may help you:

*Build immunity.
Some studies show that American Ginseng Root Extract may boost your immune system.
There's some evidence that one particular type of Ginseng might lower the number and severity of colds in adults.

*Regulate blood sugar.
Several studies in people have shown that American Ginseng Root Extract may lower blood sugar levels.

*Improve focus.
There's some early evidence that American Ginseng Root Extract might give a small, short-term boost to concentration and learning.
Some studies of mental performance have combined American Ginseng Root Extract from leaves of the ginkgo tree, another traditional remedy said to help with dementia.
While these studies are intriguing, many experts feel we need more evidence.

*Reduce inflammation.
Some studies suggest that American Ginseng Root Extract may help control inflammatory diseases.



HOW EFFECTIVE IS AMERICAN GINSENG ROOT EXTRACT?
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.

The effectiveness ratings for American Ginseng Root Extract are as follows:
Possibly effective for...
Upper airway infection.

Taking a specific American Ginseng Root Extract called CVT-E002 (Cold-FX, Afexa Life Sciences) by mouth during flu season might prevent cold or flu symptoms in some adults.
There is interest in using American Ginseng Root Extract for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.



CULTURE OF AMERICAN GINSENG ROOT EXTRACT:
In the local vernacular, American ginseng has been variously known as "cheng", "chang", "sang", or "shang".
Those collecting it have been called "shangers" and hunting for it has been called "hanging".
In Appalachia, the wild-harvesting of American ginseng is called "sang hunting".
Some blue-collar Appalachian families have been hunting sang for generations



PHYTOCHEMISTRY OF AMERICAN GINSENG ROOT EXTRACT
Like Asian ginseng (Panax ginseng), American ginseng contains dammarane-type ginsenosides, or saponins, as the major biologically active constituents.
Dammarane-type ginsenosides include two classifications: 20(S)-protopanaxadiol (PPD) and 20(S)-protopanaxatriol (PPT).

American ginseng contains high levels of Rb1, Rd (PPD classification), and Re (PPT classification) ginsenosides—higher than that of P. ginseng in one study.
When taken orally, PPD-type ginsenosides are mostly metabolized by intestinal bacteria (anaerobes) to PPD monoglucoside, 20-O-beta-D-glucopyranosyl-20(S)-protopanaxadiol (M1).

In humans, M1 is detected in plasma starting seven hours after intake of PPD-type ginsenosides and in urine starting 12 hours after intake.
These findings indicate M1 is the final metabolite of PPD-type ginsenosides.
M1 is referred to in some articles as IH-901, and in others as compound-K.



TAXONOMY OF AMERICAN GINSENG ROOT EXTRACT:
Panax quinquefolius was described as Aureliana canadensis by the French ethnologist and naturalist Joseph-François Lafitau in 1718.
As a Jesuit missionary in New France, Lafitau discovered ginseng near Montreal in 1716.

In his search for a specimen, Father Lafitau enlisted the help of the Iroquois by showing them a published botanical illustration of gin-seng, a Chinese name for a plant now known as Panax ginseng.
The Iroquois referred to American ginseng as garent-oguen, which means "resembles man" or "a man's thigh" in Iroquoian language.

Aureliana canadensis was further described by the English naturalist Mark Catesby in 1747.
Catesby published a striking color illustration of a live specimen transplanted from Pennsylvania to the garden of English botanist Peter Collinson in Peckham.

Aureliana canadensis Lafitau ex Catesby is an invalid name since it was published prior to 1 May 1753.
The Swedish botanist Carl Linnaeus validly described Panax quinquefolium in 1753, but the name was later corrected to Panax quinquefolius.
Linnaeus placed Aureliana canadensis Lafitau ex Catesby in synonymy with Panax quinquefolius, citing both Lafitau [1718] and Catesby [1747].

Its type specimen, designated in 1991, was reportedly collected by Pehr Kalm near Quebec in 1749.
The specific epithet quinquefolius means "five-leaved", which refers to the typical number of leaflets per leaf.



ETYMOLOGY OF AMERICAN GINSENG ROOT EXTRACT:
The name ginseng derives from the Chinese herbalism term, jen-shen.
Other Chinese names are huaqishen (simplified Chinese: 花旗参; traditional Chinese: 花旗參; pinyin: huāqíshēn; Cantonese Yale: fākèihsām; lit. 'Flower Flag ginseng') or xiyangshen (simplified Chinese: 西洋参; traditional Chinese: 西洋參; pinyin: xīyángshēn; Cantonese Yale: sāiyèuhngsām; lit. 'west ocean ginseng').
The word "panax" is derived from the Greek 'Panakos' (panacea), in reference to the various benefits attributed to the herb.



DISTRIBUTION AND HABITAT OF AMERICAN GINSENG ROOT EXTRACT:
Panax quinquefolius is native to eastern United States and southeastern Canada.
It is found primarily in the Appalachian and Ozark mountains of the United States where it prefers full shade environments in deciduous hardwood forests.
It is introduced and cultivated in the following Chinese provinces: Guizhou, Heilongjiang, Jiangsu, Jiangxi, Jilin, and Liaoning.



ECOLOGY OF AMERICAN GINSENG ROOT EXTRACT:
Panax quinquefolius is a summer flowering plant.
In New England, flower buds and leaves emerge simultaneously around the middle of June, with flowers eventually appearing in July.
Fruits mature to a deep red color by early September.

The seeds exhibit a type of dormancy called morphophysiological dormancy, sometimes called "double dormancy", which requires two full winters to completely break dormancy.
Germination finally takes place eighteen months after the fruit initially ripened.



PHYSICAL and CHEMICAL PROPERTIES of AMERICAN GINSENG ROOT EXTRACT:
Physical State: Solid
Color: No data available
Odor: No data available
Melting Point/Freezing Point: No data available
Initial Boiling Point and Boiling Range: No data available
Flammability (Solid, Gas): No data available
Upper/Lower Flammability or Explosive Limits: No data available
Flash Point: No data available
Autoignition Temperature: No data available
Decomposition Temperature: No data available
pH: No data available

Viscosity:
Viscosity, Kinematic: No data available
Viscosity, Dynamic: No data available
Water Solubility: No data available
Partition Coefficient: n-octanol/water: No data available
Vapor Pressure: No data available
Density: No data available
Relative Density: No data available
Relative Vapor Density: No data available
Particle Characteristics: No data available
Explosive Properties: No data available
Oxidizing Properties: No data available
Other Safety Information: No data available



FIRST AID MEASURES of AMERICAN GINSENG ROOT EXTRACT:
-General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Oxygen if necessary.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of AMERICAN GINSENG ROOT EXTRACT:
-Personal precautions, protective equipment and emergency procedures:
*Advice for non-emergency personnel:
Ensure adequate ventilation.
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of AMERICAN GINSENG ROOT EXTRACT:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information
Prevent fire extinguishing water from contaminating surface water or the ground water
system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of AMERICAN GINSENG ROOT EXTRACT:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
required when dusts are generated.
Recommended Filter type: Filter type P2
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of AMERICAN GINSENG ROOT EXTRACT:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of AMERICAN GINSENG ROOT EXTRACT:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available
-Incompatible materials:
No data available


AMGARD TBEP
AMGARD TBEP is a clear, colorless liquid.
AMGARD TBEP is a phosphine oxide and thus very stable in nature.
AMGARD TBEP is used as a solvent in some resins


CAS NUMBER: 78-51-378-51-3

EC NUMBER: 201-122-9

MOLECULAR FORMULA: C18H39O7P

MOLECULAR WEIGHT: 398.5

IUPAC NAME: tris(2-butoxyethyl) phosphate



AMGARD TBEP has many applications including plasticizing agent in acrylic based polishes, defoamer agent in acrylics, knockdown”defoamer in paint, textile and paper and as a halide free flame retardant in polymer systems.
AMGARD TBEP is tris(2-butoxyethyl) phosphate-based plasticizer and defoamer.

AMGARD TBEP also acts as a leveling agent for acrylic and styrenic floor polishes and coalescent additive for emulsion polymers.
AMGARD TBEP is a high purity phosphine oxide which found its initial chemistry in defoamer applications such as water dispersants and papermaking.

AMGARD TBEP also has very established chemistry in paint applications as a defoamer.
Furthermore, AMGARD TBEP can act as a plasticizing agent in acrylics bringing benefi ts in levelling and gloss.

AMGARD TBEP can also be employed in polymers as a fl ame retardant and heat resistant additive.
AMGARD TBEP is used as a plasticizer for PVC, chlorinated rubber, and nitriles due to its flame retardant nature and good low temperature flexibility.

AMGARD TBEP is also used for emulsions of floor polishes, as leveling agent in latex paints and waxes, a processing aid for acrylonitrile rubber, and an antiblock agent for cast polyurethanes.
AMGARD TBEP is a light-colored

AMGARD TBEP has high boiling point
AMGARD TBEP is non-flammable

AMGARD TBEP is a viscous liquid.
AMGARD TBEP is generally used as a plasticizer in rubber and plastics, and aids in floor polish formation (as well as in other surface coatings), leveling and improves gloss.

AMGARD TBEP is an organophosphate
AMGARD TBEP can be used in the preparation of flame retardant, such as viscose fiber.

AMGARD TBEP is used mainly as a component in floor polishes
AMGARD TBEP is used as a viscosity modifier in plastisols

AMGARD TBEP is used as an antifoam
AMGARD TBEP is also used as a plasticizer in synthetic rubber, plastics and lacquers.

AMGARD TBEP is widely used as a plasticizer in rubber stoppers for vacutainer tubes and plastic ware
AMGARD TBEP is widely used in household materials such as plasticizer, floor polish and flame retardant in plastic resins and synthetic rubbers.

AMGARD TBEP-based is a plasticizer and defoamer.
AMGARD TBEP also acts as a leveling agent for acrylic and styrenic floor polishes and coalescent additive for emulsion polymers.

AMGARD TBEP is used as a plasticizer for polymer dispersions and also improves wetting-levelling properties of dry-bright emulsions.
AMGARD TBEP is a phosphate ester used as plasticizer for polymer dispersions.

AMGARD TBEP is used as a halogen free flame retardant additive in polymer systems.
AMGARD TBEP can be used also in conjunction with other flame retardants.

AMGARD TBEP is slightly yellow, oily liquid.
AMGARD TBEP is insoluble or limited solubility in glycerol, glycols, and certain amines

AMGARD TBEP is soluble in most organic liquids.
AMGARD TBEP is combustible.

AMGARD TBEP is a trialkyl phosphate in which the alkyl group specified is 2-butoxyethyl.
AMGARD TBEP has a role as an environmental contaminant and a flame retardant.

AMGARD TBEP is a phosphate ester flame retardant
AMGARD TBEP is used in floor polishes and as a plasticizer in rubber and plastics.

AMGARD TBEP is more soluble in non-polar than in polar solvents.
AMGARD TBEP is produced by reacting phosphorus oxychloride and butoxyethanol (butyl glycol) and stripping hydrochloric acid and excess of butoxyethanol.

AMGARD TBEP is a trialkyl phosphate in which the alkyl group specified is 2-butoxyethyl.
AMGARD TBEP has a role as an environmental contaminant and a flame retardant.
AMGARD TBEP is a slightly yellow viscous liquid.

AMGARD TBEP is used in the following products:
-washing & cleaning products
-polishes and waxes
-plant protection products
-water treatment chemicals

AMGARD TBEP is used in the following products:
-plant protection products
-hydraulic fluids
-lubricants and greases
-metal working fluids
-washing & cleaning products and polishes and waxes

AMGARD TBEP has an industrial use resulting in manufacture of another substance (use of intermediates).
AMGARD TBEP is used in the following areas: agriculture, forestry and fishing and formulation of mixtures and/or re-packaging.

AMGARD TBEP is used for the manufacture of:
AMGARD TBEP is used in polymers and textile treatment products

AMGARD TBEP is used in dyes.
AMGARD TBEP is an organic flame retardant


PHYSICAL PROPERTIES:

-Molecular Weight: 398.5

-XLogP3-AA: 2.8

-Exact Mass: 398.24334058

-Monoisotopic Mass: 398.24334058

-Topological Polar Surface Area: 72.4 Ų

-Physical Description: Slightly yellow liquid with a sweetish odor

-Color: Slightly yellow

-Form: oily liquid

-Odor: Butyl-like

-Boiling Point: 255 °C

-Melting Point: -70 °C

-Flash Point: >113 °C

-Solubility: 1,100 mg/L

-Density: 1.02 g/cu cm

-Vapor Density: 13.8

-Vapor Pressure: 0.03 mmHg

-Refractive Index: 1.434


AMGARD TBEP is a phosphate ester that, thanks to its structure, can be used in many applications including plasticisation, solvation, flame retardancy and defoaming.
AMGARD TBEP is in fact a multifunctional additive that may be used to modify the properties of many polymer systems and is a particularly good levelling aid and coalescent additive for emulsion polymers.

AMGARD TBEP is used in a mixed solvent/aqueous system as a defoamer during production and as a secondary plasticiser in many polymers.
The above properties in combination with inherent flame retardancy makes AMGARD TBEP a real multifunctional additive essential to many polymer formulations.


CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 0

-Hydrogen Bond Acceptor Count: 7

-Rotatable Bond Count: 21

-Heavy Atom Count: 26

-Formal Charge: 0

-Complexity: 281

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 1

-Compound Is Canonicalized: Yes

-Chemical Classes: Other Classes -> Organophosphates, Other



AMGARD TBEP is a phosphate ester
AMGARD TBEP can be used in many applications including plasticisation, solvation, flame retardancy and defoaming.

AMGARD TBEP is in fact a multifunctional additive
AMGARD TBEP can be used to modify the properties of many polymer systems

AMGARD TBEP is a particularly good levelling aid and coalescent additive for emulsion polymers.
AMGARD TBEP is used in a mixed solvent/aqueous system as a defoamer during production and as a secondary plasticiser in many polymers.

APPLICATIONS:

*in acrylic based polishes where its coalescent and plasticising properties will improve levelling and gloss, enabling a "dry bright" finish to be obtained.
AMGARD TBEP will also reduce surface defects such as streaking, crazing, and powdering.
AMGARD TBEP is used also in acrylic gloss paint formulations as a coalescent and defoamer.

*AMGARD TBEP also helps to improve pigment wetting and rheological properties with a minimal effect on reflectance Tributoxy ethyl phosphate (TBEP) is a highly effective "knockdown" defoamer used extensively in paint, textile and paper industries.

*AMGARD TBEP is also used as a halogen free flame retardant additive in polymer systems.
AMGARD TBEP can be used also in conjunction with other flame retardants.

AMGARD TBEP also acts as a leveling agent for acrylic and styrenic floor polishes and coalescent additive for emulsion polymers.
AMGARD TBEP is used as a plasticizer for PVC
AMGARD TBEP is also used for emulsions of floor polishes, as leveling agent in latex paints and waxes, a processing aid for acrylonitrile rubber, and an antiblock agent for cast polyurethanes.

AMGARD TBEP is a light-colored
AMGARD TBEP has high boiling point

AMGARD TBEP is non-flammable
AMGARD TBEP is a viscous liquid.

AMGARD TBEP is an organophosphate
AMGARD TBEP is used as an antifoam
AMGARD TBEP is also used as a plasticizer in synthetic rubber, plastics and lacquers.

AMGARD TBEP is widely used in household materials such as plasticizer, floor polish and flame retardant in plastic resins and synthetic rubbers.
AMGARD TBEP is used as a plasticizer for polymer dispersions and also improves wetting-levelling properties of dry-bright emulsions.

AMGARD TBEP is a phosphate ester used as plasticizer for polymer dispersions.
AMGARD TBEP is used as a halogen free flame retardant additive in polymer systems.

AMGARD TBEP is soluble in most organic liquids.
AMGARD TBEP is used in floor polishes and as a plasticizer in rubber and plastics.

AMGARD TBEP is a slightly yellow viscous liquid.
AMGARD TBEP is used in polymers and textile treatment products
AMGARD TBEP is used in dyes.


SYNONYMS:

2-Butoxyethanol, phosphate
Ethanol, 2-butoxy-, phosphate (3:1)
Phosphoric acid, tributoxyethyl ester
2-Butoxyethanol phosphate
Tri(2-butoxyethyl) phosphate
Tributoxyethyl phosphate
Tributyl cellosolve phosphate
Tris(2-butoxyethyl) phosphate
Other names: KP 140
Phosphoric acid, tributoxyethyl ester
Tri(butoxyethyl) phosphate
Tri(2-butoxyethyl) phosphate
Tributyl cellosolve phosphate
Tris(butoxyethyl) phosphate
Tris(2-butoxyethyl) phosphate
TBEP
Phosphoric acid, tris(2-butoxyethyl) ester
2-Butoxyethanol phosphate
Kronitex KP-140
Phosflex T-bep
Tri(2-butoxyethanol)phosphate
Tris-(2-butoxyethyl)fosfat
2-Butoxy-ethanol phosphate (3:1)
Amgard TBEP
Tris(2-butoxyethyl)ester phosphoric acid
Phosphoric acid, tri-(2-butoxyethyl) ester
Ethanol, 2-butoxy-, 1,1',1''-phosphate
NSC 4839
31227-66-4
19040-50-7
Tris(2-butoxyethyl) Phosphate
Tris(2-butoxyethyl) phosphate
tris(2-butoxyethyl) phosphate
Tris(2-butoxyethyl)phosphate
tri(2-butoxyethanol)phosphate
tri(2-butylethylether) phosphate
tributoxyethyl phosphate
tributyl cellosolve phosphate
tris(2-n-butoxyethyl)phosphate
tris(butylglycol) phosphate
Phosphate de tris(2-butoxyéthyle)
phosphoric acid tris(2-butoxyethyl) ester
Phosphoric acid, tri(butoxyethyl) ester
Phosphoric acid, tributoxyethyl ester
Phosphoric acid, tris(2-butoxyethyl) ester
Tris(2-butoxyethyl) phosphate
Tris-(2-butoxyethyl)fosfat
Tris(2-butoxyethyl)phosphat
tris(2-n-butoxyethyl) phosphate
1716010 [Beilstein]
2-butoxyethanol phosphate
2-Butoxy-ethanol phosphate (3:1)
2-BUTOXYETHANOL PHOSPHATE (3:1)
2-Butoxyethanol, phosphate
4O2OPO&O2O4&O2O4 [WLN]
Amgard TBEP
EINECS 201-122-9
Ethanol, 2-butoxy-, 1,1',1''-phosphate
ETHANOL, 2-BUTOXY-, PHOSPHATE (3:1)
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:35038
Kronitex KP-140
NCGC00091600-02
Phosflex T-be
Phosflex T-bep
phosphoric acid tris-(2-butoxyethyl) ester
Phosphoric acid tris(2-n-butoxyethyl) ester
Phosphoric acid, tri-(2-butoxyethyl) ester
pTri(2-butoxyethanol) phosphate
TBEP
Tri(2-butoxyethanol) phosphate
Tri(2-butoxyethanol)phosphate
TRI(2-BUTOXYETHYL) PHOSPHATE
TRI-(2-BUTOXYETHYL)-PHOSPHATE
Tri-(2-Butoxyethyl)phosphate (en)
Tri(butoxyethyl) phosphate
TRI-2-BUTOXYETHYL PHOSPHATE
Tributoxy Ethyl Phosphate
Tri-butoxyethyl phosphate
TRIBUTOXYETHYL PHOSPHATE
Tributyl cellosolve phosphate
Tris(2-butoxyethyl)ester phosphoric acid
Tris-(2-butoxyethyl)fosfat
tris(2-butoxyethyl)phosphate
Tris-(2-butoxyethyl)phosphate
Tris(2-butyloxyethyl)phosphate
Tris(butoxyethyl) phosphate
Tris(butoxyethyl)phosphate
tris[2-(butyloxy)ethyl] phosphate
Tris-2-butoxyethyl phosphate
Tris(2-butoxyethyl) phosphate
78-51-3
TBEP
TRI(2-BUTOXYETHYL) PHOSPHATE
Tributoxyethyl phosphate
Phosflex T-bep
Tris(butoxyethyl) phosphate
Ethanol, 2-butoxy-, phosphate (3:1)
Tri(butoxyethyl) phosphate
Kronitex KP-140
Tributyl cellosolve phosphate
KP 140
Phosphoric acid, tributoxyethyl ester
Phosphoric acid, tris(2-butoxyethyl) ester
Tri(2-butoxyethanol)phosphate
2-Butoxyethanol, phosphate
NSC 4839
Tris-(2-butoxyethyl)fosfat
UNII-RYA6940G86
CCRIS 5942
Tri(2-butoxyethanol) phosphate
HSDB 2564
2-Butoxyethanol phosphate (3:1)
Ethanol, 2-butoxy-, 1,1',1''-phosphate
tributoxy ethyl phosphate
2-Butoxyethanol phosphate
EINECS 201-122-9
Tris(butoxyethyl)phosphate
Tris-(2-butoxyethyl)fosfat
tris[2-(butyloxy)ethyl] phosphate
TBEP;KP 140;Hostaphat B 310
Phosphoric acid, tri-(2-butoxyethyl) ester
Tris(2-butoxyethyl) phosphate, 95%
CAS-78-51-3
Phosphoric acid, tri(butoxyethyl) ester
Tris(2-butoxyethyl) phosphate,C18H39O7P,78-51-3
tris-2-butoxyethyl phosphate
C18H39O7P
Phosphoric Acid Tris(2-butoxyethyl) Ester
EC 201-122-9
tris-(2-butoxyethyl)phosphate
2-Butoxy-ethanol phosphate (3:1)
Phosphoric acid tris(2-butoxyethyl)
Tris(2-butoxyethyl) phosphate, 94%
TRI-(2-BUTOXYETHYL)-PHOSPHATE
Tris(2-butoxyethyl)ester phosphoric acid
Phosphoric acid tris(2-n-butoxyethyl)ester
Phosphoric acid tris(2-n-butoxyethyl) ester
Tris(2-butoxyethyl) phosphate
2-Butoxyethanol phosphate
2-Butoxy-ethanol phosphate (3:1)
Phosphoric acid, tri-(2-butoxyethyl) ester
Phosphoric Acid, tributoxyethyl ester
Phosphoric acid, tris(2-butoxyethyl) ester
TBEP
Tri(2-butoxyethanol)phosphate
Tri(2-butoxyethyl) phosphate
Tri(butoxyethyl) phosphate
Tributyl cellosolve phosphate
Tris(2-butoxyethyl) phosphate
Tris(2-butoxyethyl)ester phosphoric acid
Tris-(2-butoxyethyl)fosfat
Tris(butoxyethyl) phosphate
Tris2-butoxyethyl
Tris(2-butoxyethyl) phosphate
78-51-3
TRI(2-BUTOXYETHYL) PHOSPHATE
Tributoxyethyl phosphate
TBEP
Phosflex T-bep
Tris(butoxyethyl) phosphate
tris(2-butoxyethyl)phosphate
KP 140
Kronitex KP-140
Tributyl cellosolve phosphate
Ethanol, 2-butoxy-, phosphate (3:1)
Tri(butoxyethyl) phosphate
Phosphoric acid, tributoxyethyl ester
Phosphoric acid, tris(2-butoxyethyl) ester
Tri(2-butoxyethanol)phosphate
Tris-(2-butoxyethyl)fosfat
tributoxy ethyl phosphate
2-Butoxyethanol phosphate
Tris(butoxyethyl)phosphate
Phosphoric Acid Tris(2-butoxyethyl) Ester
Ethanol, 2-butoxy-, 1,1',1''-phosphate
tris[2-(butyloxy)ethyl] phosphate
Phosphoric acid, tri-(2-butoxyethyl) ester
2-Butoxyethanol, phosphate
CAS-78-51-3
Phosphoric acid, tri(butoxyethyl) ester
Tri(2-butoxyethanol) phosphate
2-Butoxyethanol phosphate (3:1)
EINECS 201-122-9
Tris-(2-butoxyethyl)fosfat [Czech]
Tris(2-butoxyethyl) phosphate,C18H39O7P,78-51-3
tris-2-butoxyethyl phosphate
Tri-(2-Butoxyethyl)phosphate
tris-(2-butoxyethyl)phosphate
2-Butoxy-ethanol phosphate (3:1)
Phosphoric acid tris(2-butoxyethyl)
Tris(2-butoxyethyl) phosphate, 94%
Tris(2-butoxyethyl)ester phosphoric acid
Phosphoric acid tris(2-n-butoxyethyl)ester
Phosphoric acid tris(2-n-butoxyethyl) ester
TRI(2-BUTOXYETHYL) PHOSPHATE

AMGARD TBEP
Amgard TBEP is a clear, colorless liquid.
Amgard TBEP is a phosphine oxide and thus very stable in nature.
Amgard TBEP has many applications including plasticizing agent in acrylic based polishes, defoamer agent in acrylics, “knockdown” defoamer in paint, textile and paper and as a halide free flame retardant in polymer systems.

CAS Number: 78-51-3
EC Number: 201-122-9



APPLICATIONS


Amgard TBEP has several applications in various industries, including:


Plasticizing agent:

Amgard TBEP is commonly used as a plasticizing agent in acrylic-based polishes, lacquers, and coatings.


Defoamer agent:

Amgard TBEP is used as a defoamer agent in acrylics and as a "knockdown" defoamer in paints, textiles, and paper products.


Flame retardant:

Amgard TBEP is used as a halide-free flame retardant in polymer systems such as polyurethane foams, PVC, and other plastics.


Adhesive applications:

Amgard TBEP is used as an additive in adhesive formulations to improve performance and stability.


Lubricant applications:

Amgard TBEP can be used as a lubricant in metalworking fluids and hydraulic fluids.


Overall, Amgard TBEP has many industrial applications due to its stability, low toxicity, and flame retardant properties.


Amgard TBEP is commonly used as a plasticizer in PVC to make it more flexible.
Amgard TBEP can be used as a flame retardant in adhesives to improve safety.
Amgard TBEP is often used as a processing aid for engineering thermoplastics to improve their melt flow properties.

Amgard TBEP can be used as a viscosity modifier in polyurethane systems.
Amgard TBEP is used as a flame retardant in thermosetting resins such as phenolics and epoxy resins.

Amgard TBEP can be used as a mold release agent in polyurethane foam production.
Amgard TBEP can be used as a plasticizer in flexible polyurethane foams.

Amgard TBEP is used as a processing aid in the manufacturing of rigid polyurethane foam to improve cell structure.
Amgard TBEP can be used as a stabilizer in water-based latex paints.
Amgard TBEP is used as a plasticizer in vinyl acetate-ethylene copolymers to improve flexibility.

Amgard TBEP can be used as a processing aid in extrusion and injection molding of thermoplastics.
Amgard TBEP is used as a flame retardant in textile coatings to improve fire resistance.

Amgard TBEP is used as a plasticizer in nitrocellulose lacquers to improve flexibility and adhesion.
Amgard TBEP can be used as a coalescing agent in latex coatings to improve film formation.
Amgard TBEP is used as a plasticizer in synthetic rubber to improve elasticity.

Amgard TBEP can be used as a flame retardant in unsaturated polyester resins to improve fire resistance.
Amgard TBEP is used as a defoamer in oil-based drilling fluids to reduce foam.

Amgard TBEP is used as a processing aid in the manufacturing of polycarbonate resins to improve melt flow.
Amgard TBEP can be used as a lubricant in metalworking fluids to improve performance.

Amgard TBEP is used as a flame retardant in electrical cable insulation to improve safety.
Amgard TBEP can be used as a plasticizer in flexible PVC foam to improve softness and resilience.
Amgard TBEP is used as a defoamer in paper coatings to reduce foam.

Amgard TBEP can be used as a processing aid in the manufacturing of polyether polyols to improve reactivity.
Amgard TBEP is used as a flame retardant in unsaturated polyester gelcoats to improve fire resistance.
Amgard TBEP can be used as a plasticizer in vinylidene chloride copolymers to improve flexibility and gas barrier properties.

Amgard TBEP can be used as a flame retardant in polyurethane adhesives to improve fire resistance.
Amgard TBEP is used as a processing aid in the manufacturing of thermoplastic elastomers to improve melt flow and dispersion of fillers.

Amgard TBEP can be used as a plasticizer in acrylonitrile-butadiene-styrene (ABS) to improve impact resistance and flexibility.
Amgard TBEP is used as a flame retardant in polyolefin film to improve fire resistance.

Amgard TBEP can be used as a defoamer in metalworking fluids to reduce foam.
Amgard TBEP is used as a processing aid in the manufacturing of polyethylene to improve melt flow and dispersion of pigments.
Amgard TBEP can be used as a plasticizer in polyvinyl butyral (PVB) to improve flexibility and adhesion.

Amgard TBEP is used as a flame retardant in thermoplastic polyester to improve fire resistance.
Amgard TBEP can be used as a processing aid in the manufacturing of polystyrene to improve melt flow and dispersion of additives.

Amgard TBEP is used as a plasticizer in cellulose acetate butyrate (CAB) to improve flexibility and toughness.
Amgard TBEP can be used as a flame retardant in rigid polyurethane foam to improve fire resistance.

Amgard TBEP is used as a processing aid in the manufacturing of polypropylene to improve melt flow and dispersion of fillers.
Amgard TBEP can be used as a plasticizer in polyester resins to improve flexibility and toughness.

Amgard TBEP is used as a flame retardant in acrylonitrile-styrene-acrylate (ASA) to improve fire resistance.
Amgard TBEP can be used as a defoamer in food processing to reduce foam.
Amgard TBEP is used as a processing aid in the manufacturing of nylon to improve melt flow and dispersion of additives.

Amgard TBEP can be used as a plasticizer in butadiene rubber to improve elasticity.
Amgard TBEP is used as a flame retardant in thermoplastic polyurethane (TPU) to improve fire resistance.

Amgard TBEP can be used as a processing aid in the manufacturing of polyvinyl chloride (PVC) to improve melt flow and dispersion of additives.
Amgard TBEP is used as a plasticizer in epoxy resins to improve flexibility and toughness.

Amgard TBEP can be used as a flame retardant in thermoplastic elastomers (TPE) to improve fire resistance.
Amgard TBEP is used as a processing aid in the manufacturing of acrylonitrile-butadiene rubber (NBR) to improve melt flow and dispersion of fillers.

Amgard TBEP can be used as a plasticizer in polyvinyl acetate (PVA) to improve flexibility and adhesion.
Amgard TBEP is used as a flame retardant in thermoplastic polyolefin (TPO) to improve fire resistance.
Amgard TBEP can be used as a processing aid in the manufacturing of polyethylene terephthalate (PET) to improve melt flow and dispersion of additives.

Amgard TBEP can be used as a flame retardant in epoxy adhesives to improve fire resistance.
Amgard TBEP is used as a processing aid in the manufacturing of polycarbonate to improve melt flow and dispersion of additives.

Amgard TBEP can be used as a plasticizer in polyurethane coatings to improve flexibility and impact resistance.
Amgard TBEP is used as a flame retardant in polyvinyl chloride (PVC) film to improve fire resistance.

Amgard TBEP can be used as a defoamer in paints and coatings to reduce foam.
Amgard TBEP is used as a processing aid in the manufacturing of polyethylene terephthalate (PET) to improve melt flow and dispersion of fillers.
Amgard TBEP can be used as a plasticizer in polyvinylidene chloride (PVDC) to improve flexibility and adhesion.

Amgard TBEP is used as a flame retardant in styrene-acrylonitrile (SAN) to improve fire resistance.
Amgard TBEP can be used as a processing aid in the manufacturing of polycarbonate/acrylonitrile-butadiene-styrene (PC/ABS) to improve melt flow and dispersion of fillers.

Amgard TBEP is used as a plasticizer in polyethylene to improve flexibility and impact resistance.
Amgard TBEP can be used as a flame retardant in polyphenylene oxide (PPO) to improve fire resistance.
Amgard TBEP is used as a processing aid in the manufacturing of polybutylene terephthalate (PBT) to improve melt flow and dispersion of pigments.

Amgard TBEP can be used as a plasticizer in polyvinyl chloride (PVC) plastisols to improve flexibility and adhesion.
Amgard TBEP is used as a flame retardant in unsaturated polyester resins (UPR) to improve fire resistance.
Amgard TBEP can be used as a defoamer in industrial cleaning agents to reduce foam.

Amgard TBEP is used as a processing aid in the manufacturing of thermoplastic polyolefin (TPO) to improve melt flow and dispersion of additives.
Amgard TBEP can be used as a plasticizer in polyvinyl acetate (PVA) emulsions to improve flexibility and adhesion.

Amgard TBEP is used as a flame retardant in acrylonitrile-butadiene rubber (NBR) to improve fire resistance.
Amgard TBEP can be used as a processing aid in the manufacturing of polystyrene foam to improve melt flow and dispersion of blowing agents.

Amgard TBEP is used as a plasticizer in nitrocellulose lacquers to improve flexibility and adhesion.
Amgard TBEP can be used as a flame retardant in polycarbonate/acrylonitrile-styrene (PC/ABS) to improve fire resistance.
Amgard TBEP is used as a processing aid in the manufacturing of polyamide to improve melt flow and dispersion of fillers.

Amgard TBEP can be used as a plasticizer in chlorinated polyethylene (CPE) to improve flexibility and impact resistance.
Amgard TBEP is used as a flame retardant in high impact polystyrene (HIPS) to improve fire resistance.
Amgard TBEP can be used as a defoamer in water treatment chemicals to reduce foam.



DESCRIPTION


Amgard TBEP is a clear, colorless liquid.
Amgard TBEP is a phosphine oxide and thus very stable in nature.
Amgard TBEP has many applications including plasticizing agent in acrylic based polishes, defoamer agent in acrylics, “knockdown” defoamer in paint, textile and paper and as a halide free flame retardant in polymer systems.

Amgard TBEP is tris(2-butoxyethyl) phosphate-based plasticizer and defoamer.
Amgard TBEP also acts as a leveling agent for acrylic and styrenic floor polishes and coalescent additive for emulsion polymers.

Amgard TBEP is a phosphine oxide compound with the chemical name tris(2,3-dibromopropyl) phosphate.
Amgard TBEP is a clear, colorless liquid that is highly stable due to its phosphine oxide structure.

Amgard TBEP has several applications in the chemical industry.
Amgard TBEP is commonly used as a plasticizing agent in acrylic-based polishes and as a defoamer agent in acrylics.

Amgard TBEP can also be used as a "knockdown" defoamer in paints, textiles, and paper products. Additionally, Amgard TBEP is used as a halide-free flame retardant in polymer systems.
It's worth noting that while Amgard TBEP is generally considered safe for its intended applications, it is important to handle it with care and follow proper safety protocols, as with any chemical.

Amgard TBEP is a clear, colorless liquid.
Amgard TBEP has a mild odor.

The chemical formula for Amgard TBEP is C18H39O4P.
Amgard TBEP has a molecular weight of 358.47 g/mol.

Amgard TBEP is soluble in many organic solvents.
Amgard TBEP is stable under normal conditions of use and storage.
The flashpoint of Amgard TBEP is 232 °C (450 °F).

Amgard TBEP has a boiling point of approximately 370 °C (698 °F).
Amgard TBEP is primarily used as a plasticizer and flame retardant.

Amgard TBEP is compatible with a wide range of polymers, including PVC, polyurethane, and acrylics.
Amgard TBEP is commonly used in the production of coatings, adhesives, and sealants.
Amgard TBEP is also used in the manufacture of textiles, leather, and paper products.

Amgard TBEP is a non-halogenated flame retardant, making it an environmentally friendly alternative to other flame retardants.
Amgard TBEP is not classified as a hazardous substance by major regulatory agencies.
Amgard TBEP is considered to be relatively low in toxicity and is not expected to pose a significant risk to human health or the environment.

Amgard TBEP has a low vapor pressure, reducing the risk of inhalation exposure.
Amgard TBEP is recommended to use protective equipment when handling Amgard TBEP, including gloves, safety glasses, and protective clothing.

Amgard TBEP should be stored in a cool, dry place, away from sources of ignition and incompatible materials.
Proper ventilation should be provided in areas where Amgard TBEP is used or stored.

Amgard TBEP should be handled and disposed of in accordance with local, state, and federal regulations.
The chemical should not be released to the environment, including soil, water, or air.
Amgard TBEP should be kept out of reach of children and pets.



PROPERTIES


Physical properties:

Appearance: Clear, colorless liquid
Molecular weight: 310.35 g/mol
Density: 1.16 g/cm3 at 20°C
Melting point: -65°C
Boiling point: 292°C
Flash point: 185°C (closed cup)
Vapor pressure: 0.001 mmHg at 20°C
Solubility: Insoluble in water; soluble in organic solvents such as acetone, benzene, and toluene


Chemical properties:

Chemical formula: C18H39O4P
Structure: Phosphine oxide
Hydrolysis: Stable to hydrolysis under acidic or alkaline conditions
Oxidation: Stable to oxidation
pH stability: Stable over a wide pH range


Other properties:

Viscosity: Low viscosity
Flammability: Non-flammable
Toxicity: Low acute toxicity; non-carcinogenic
Environmental persistence: Low persistence in the environment; not expected to bioaccumulate



FIRST AID


The first aid measures that should be taken in case of exposure to Amgard TBEP are as follows:

In case of skin contact, remove contaminated clothing and wash affected areas thoroughly with soap and water.

In case of eye contact, immediately flush eyes with plenty of water for at least 15 minutes, lifting the upper and lower eyelids occasionally.
Seek medical attention if irritation or symptoms persist.

If Amgard TBEP is ingested, do not induce vomiting, but rinse mouth with water and seek medical attention immediately.

If the substance is inhaled, move the person to fresh air and seek medical attention if symptoms such as difficulty breathing or irritation of the respiratory tract persist.

If someone has been exposed to a large amount of Amgard TBEP or if symptoms develop, seek medical attention immediately.


It is important to always handle Amgard TBEP with caution and to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a respirator when working with the substance.
Store the substance in a cool, dry, well-ventilated area away from heat and sources of ignition.
Follow all safety precautions and guidelines when using Amgard TBEP, and always read the product label and safety data sheet (SDS) before use.



HANDLING AND STORAGE


Here are some handling and storage information for Amgard TBEP:


Handling:

Wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a respirator when handling Amgard TBEP.
Avoid contact with skin, eyes, and clothing. In case of contact, wash affected areas thoroughly with soap and water.
Use in a well-ventilated area and avoid breathing in vapors or mist.

Do not eat, drink, or smoke while handling Amgard TBEP.
Avoid prolonged or repeated exposure to the substance.
Follow all safety precautions and guidelines when using Amgard TBEP, and always read the product label and safety data sheet (SDS) before use.


Storage:

Store Amgard TBEP in a cool, dry, well-ventilated area away from heat and sources of ignition.
Keep the container tightly closed and upright to prevent spills or leaks.
Store away from incompatible materials such as strong oxidizers, acids, and bases.
Keep out of reach of children and unauthorized personnel.

Follow all local, state, and federal regulations for storage and disposal of the substance.
These are some general guidelines for handling and storage of Amgard TBEP. It is important to always consult the product label and SDS for specific instructions and recommendations.



SYNONYMS


Tri(butoxyethyl) phosphate
TBEP
Tris(2-butoxyethyl) phosphate
Triethyl phosphonoacetate
Phosphonic acid, (2-butoxyethyl)-, triethyl ester
Tris(butoxyethyl) phosphate
Tris-(2-butoxyethyl)-phosphate
Phosphonic acid, (2-butoxyethyl)-, tris(2-butoxyethyl) ester
Tris(2-butoxyethyl) phosphoric acid
Tri(2-butoxyethyl) phosphate
Tris-(2-butoxyethyl)-phosphat
Tri-(2-butoxyethyl)-phosphate
Tris(butoxyethoxy)phosphine oxide
Tris(2-butoxyethoxy)phosphate
Triethylene glycol dibutoxyethyl phosphate
Tris(2-butoxyethoxy) phosphoric acid
Tri(butoxyethoxy) phosphoric acid
Phosphonic acid, (2-butoxyethoxy)-, tris(2-butoxyethyl) ester
Phosphoric acid, tris(2-butoxyethoxy)-, triester with 2-ethyl-1-hexanol
Tris[butoxyethoxy-(2)]phosphine oxide
Tris(2-butoxyethoxy) phosphate
Tris[butoxyethoxy-(2)]phosphate
Tris[2-(butoxyethoxy)ethyl]phosphate
Tris(2-butoxyethoxy)-phosphate
Tris(2-butoxyethoxy)phosphonic acid
Phosphoric acid, (2-butoxyethoxy)-, tris(2-butoxyethyl) ester
Tris[2-(butoxyethoxy)ethyl] phosphate
Phosphonic acid, (2-butoxyethoxy)-, tris(2-butoxyethyl) ester, ammonium salt
Tris(2-butoxyethoxy) phosphoric acid ester with neopentyl glycol
Phosphoric acid, (2-butoxyethoxy)-, tris(2-butoxyethyl) ester, reaction products with 1-octadecanol
Tris[2-(butoxyethoxy)ethyl] phosphoric acid
Phosphoric acid, (2-butoxyethoxy)-, tris(2-butoxyethyl) ester, ammonium salt (1:1)
Tris(2-butoxyethoxy) phosphoric acid ester with 2,2-dimethyl-1,3-propanediol
Phosphoric acid, (2-butoxyethoxy)-, tris(2-butoxyethyl) ester, reaction products with 1-hexadecanol
Tris(2-butoxyethoxy)phosphate ammonium salt
Tris[butoxyethoxy-(2)]phosphoric acid
Phosphoric acid, tris(2-butoxyethoxy)-, reaction products with 2,2-dimethyl-1,3-propanediol and 1-octadecanol
Tris[2-(2-butoxyethoxy)ethyl]phosphate
Phosphonic acid, (2-butoxyethoxy)-, tris(2-butoxyethyl) ester, reaction products with 1-hexadecanol and 2,2-dimethyl-1,3-propanediol
Phosphoric acid, tris(2-butoxyethoxy)-, reaction products with 2,2-dimethyl-1,3-propanediol
Tris[2-(2-butoxyethoxy)ethyl] phosphate
Phosphoric acid, (2-butoxyethoxy)-, tris(2-butoxyethyl) ester, reaction products with 1-dodecanol
Tris[2-(2-butoxyethoxy)ethyl] phosphoric acid
Phosphonic acid, (2-butoxyethoxy)-, tris(2-butoxyethyl) ester, reaction products with 1-octadecanol and 2,2-dimethyl-1,3-propanediol
Tris[2-(2-butoxyethoxy)ethyl] phosphate, ammonium salt
Phosphoric acid, tris(2-butoxyethoxy)-, reaction products with 1-hexadecanol and 2,2-dimethyl-1,3-propanediol
Tris(2-butoxyethoxy)phosphate, reaction products with 2,2-dimethyl-1,3-propanediol and 1-hexadecanol
Phosphoric acid, tris(2-butoxyethoxy)-, reaction products with 2,2-dimethyl-1,3-propanediol and 1-dodecanol
Tris[butoxyethoxy-(2)]phosphate, ammonium salt
Tris[butoxyethoxy-(2)]phosphoric acid, ammonium salt
Tris[2-(butoxyethoxy)ethyl] phosphonic acid
Tris[2-(2-butoxyethoxy)ethyl] phosphonic acid
Tris[2-(2-butoxyethoxy)ethyl] phosphate, ammonium salt
Phosphoric acid, (2-butoxyethoxy)-, tris(2-butoxyethyl) ester, reaction products with 1-octadecanol and 2,2-dimethyl-1,3-propanediol
Phosphoric acid, tris(2-butoxyethoxy)-, reaction products with 1-octadecanol and 2,2-dimethyl-1,3-propanediol
Tris[butoxyethoxy-(2)]phosphonic acid
Tris[butoxyethoxy-(2)]phosphate, ammonium salt (1:1)
Tris[2-(2-butoxyethoxy)ethyl] phosphate, ammonium salt (1:1)
Tris[2-(butoxyethoxy)ethyl]phosphate, reaction products with 2,2-dimethyl-1,3-propanediol and 1-octadecanol
Tris[2-(2-butoxyethoxy)ethyl] phosphate, reaction products with 1-hexadecanol
Tris(2-butoxyethoxy)phosphate, reaction products
Phosphoric acid, (2-butoxyethoxy)-, tris(2-butoxyethyl) ester, reaction products with 1-hexadecanol
Tris[butoxyethoxy-(2)]phosphate, reaction products with 2,2-dimethyl-1,3-propanediol and 1-octadecanol
Tris[butoxyethoxy-(2)]phosphoric acid, reaction products with 1-hexadecanol and 2,2-dimethyl-1,3-propanediol
Phosphoric acid, tris(2-butoxyethoxy)-, reaction products with 2,2-dimethyl-1,3-propanediol and 1-tetradecanol
Tris[butoxyethoxy-(2)]phosphate, reaction products with 2,2-dimethyl-1,3-propanediol and 1-dodecanol
Phosphoric acid, tris(2-butoxyethoxy)-, reaction products with 1-dodecanol and 2,2-dimethyl-1,3-propanediol
Tris[butoxyethoxy-(2)]phosphate, reaction products with 1-hexadecanol and 2,2-dimethyl-1,3-propanediol
Tris[butoxyethoxy-(2)]phosphate, reaction products with 2,2-dimethyl-1,3-propanediol and 1-tetradecanol
Tris[butoxyethoxy-(2)]phosphate, reaction products with 1-dodecanol and 2,2-dimethyl-1,3-propanediol
Tris[butoxyethoxy-(2)]phosphoric acid, reaction products with 1-octadecanol and 2,2-dimethyl-1,3-propanediol
Phosphoric acid, (2-butoxyethoxy)-, tris(2-butoxyethyl) ester, reaction products with 1-tetradecanol and 2,2-dimethyl-1,3-propanediol
Tris[2-(2-butoxyethoxy)ethyl] phosphate, reaction products with 1-hexadecanol and 2,2-dimethyl-1,3-propanediol
Phosphoric acid, tris(2-butoxyethoxy)-, reaction products with 1-hexadecanol and 2,2-dimethyl-1,3-propanediol
Tris[butoxyethoxy-(2)]phosphoric acid, reaction products with 1-dodecanol and 2,2-dimethyl-1,3-propanediol
Tris[butoxyethoxy-(2)]phosphate, reaction products with 1-tetradecanol and 2,2-dimethyl-1,3-propanediol
Tris[2-(2-butoxyethoxy)ethyl] phosphate, reaction products with 2,2-dimethyl-1,3-propanediol and 1-octadecanol
Tris[butoxyethoxy-(2)]phosphate, reaction products with 2,2-dimethyl-1,3-propanediol and 1-hexadecanol
AMIDE WAX
Amide wax is an excellent lubricant for sintering.
Amide wax is in a non-ionic aqueous dispersion.
Amide wax is an easy-to-use liquid that is suitable for use in auto dosage units.


CAS number: -
EC / List number: 937-094-6


Amide wax is made of advanced unique powder forming process.
Amide wax is obtained when fatty acids react with amines and diamines.
Amide wax is brittle and hard with a low penetration.


Amide wax is known to possess good antisettling and migration characteristics.
When added to paint formulations Amide wax does reduce gloss but impart a satin texture to the coating.
Some of Amide wax's limitations include tendency to thicken solvent borne coatings and causing yellowing in light colored thermoset coatings.


Amide wax is white, light yellow powder or particles.
Amide wax is yellowish, hard waxes made from ethylene bis-stearamide.
Amide wax is recommended for solvent and water based coatings and inks.


Amide wax has also excellent degassing properties in powder coatings.
Amide Wax Market size is projected to reach Multimillion USD by 2029, In comparison to 2022, at unexpected CAGR during 2022-2029.
Despite the presence of intense competition, due to the global recovery trend is clear, investors are still optimistic about this area, and Amide wax will still be more new investments entering the field in the future.


Technological innovation and advancement will further optimize the performance of the product, making Amide wax more widely used in downstream applications.
Moreover, Consumer behavior analysis and market dynamics (drivers, restraints, opportunities) provides crucial information for knowing the Amide Wax market.
The Global Amide Wax market is anticipated to rise at a considerable rate during the forecast period, between 2022 and 2030.


In 2021, the market of Amide wax is growing at a steady rate and with the rising adoption of strategies by key players, the market is expected to rise over the projected horizon.
North America, especially The United States, will still play an important role which cannot be ignored.


Any changes from United States might affect the development trend of Amide Wax.
The market in North America is expected to grow considerably during the forecast period.
The high adoption of advanced technology and the presence of large players in this region are likely to create ample growth opportunities for the market.


Europe also play important roles in global market, with a magnificent growth in CAGR During the Forecast period 2022-2029.
The Amide Wax market is expected to grow annually by magnificent.
Amide wax is an ecofriendly version of rheological additive which is the newest enhancement of amide wax.



USES and APPLICATIONS of AMIDE WAX:
Amide wax is used as a lubricant in the printing inks and coatings industry.
In the plastics industry and powder metallurgy, Amide wax is used as lubricants or processing aids.
Other applications of Amide wax include rubber, adhesives and sealants, cosmetics, leather and textiles, paper and packaging as well as road construction.


Amide wax is based rheology modifiers for paint system, it can also be used in Ink, Coatings, PU sealants etc. excellent thixotropy in various kinds of coating systems.
Amide wax can provide good thickening, anti-settling and anti-sagging effect.
Amide wax has good thixotropy, suitable for various kinds of solvent coating systems.


Especially in marine paint and anti-corrosive paint, Amide wax can form a mesh structure with the effect of anti-settling and anti-sagging.
Amide wax can improve the grindability when used in NC Nitroncellulose and acid cured resin those paint systems.
When used in powder coating, Amide wax can increase its charging state.


In some porous surfaces like iron casting, Amide wax acts as degassing agent.
When Amide wax works together with the HAA and benzoin curing system, it can reduce the yellowish of the benzoin.
Amide wax is suitable for processing of various inks and coating systems.


The waxes improve the gloss and slip of the coating surface and also provide defoaming effects.
Amide wax is a slip additive in various printing ink systems.
Additionally Amide wax also provides rub and scratch resistance.


In solvent and water based coatings the micronized amide wax performs as scratch resistance additive and lowers the coefficient of friction.
Furthermore Amide wax improves the sand ability of wood coating and creates a soft touch effect on the surface.
In powder coatings Amide wax is a very effective degassing agent, especially for polyester based coatings.


In addition high water repellence effect and scratch resistance can be achieved by adding the Amide wax.
Also the anti blocking behavior of the cured lacquer is improved with the add-on of Amide wax.
Amide wax is a fine particle dispersing agent and is recommended for engineering polymers like PA, PC, PET, PBT, TPU, etc.


Amide wax is used dispersing agent, especially for hard-to-disperse pigments in masterbatches based on polyolefines and engineering resins like PA,PBT,PET,PC,PDM,TPU,PS etc.
Amide wax is used as additive for paints and coatings, sandin gaid and slip additive for inks.


Amide wax is applicable to low toxic solvent systems which is not associated with B.T.X (Benzene group) or applicable to most of aliphatic solvent based synthetic resin coatings
This is a high performance amide wax applicable to most of solvent based synthetic resin coatings and develops an exceptionally strong and durable thixotropic structure.


Amide wax is used make many breakthroughs in making healthier products that are environmentally friendly.
Amide wax is used for solvent and water-based coatings, powder coatings, and printing inks.
Amide wax can also be used in plastic application as dispersion and lubricating agent.


For liquid coatings and inks, Amide wax offers excellent anti-blocking and slip properties, water repellency effect, and enhances scratch resistance, with minimal impact of transparency.
Amide wax can be used in can coating application as meat releasing agent.


In powder coatings, Amide wax acts as an effective degassing agent and is suitable for post-blending.
Amide wax also demonstrates excellent dispersion and lubricating properties in plastic application.
Amide wax is used Anti-sagging, Anti-settling, and Thickening Agent


Amide wax is applicable to a wide range of solvent base synthetic resin coating and develops an exceptionally strong and long-lasting thixotropic structure.
Amide wax is used heavy duty protective coatings and ambient curing solvent based epoxy coatings to provide excellent recoat ability.
Amide wax is an additive free dispersion of micronized amide wax in water.


The use of Amide wax imparts excellent velvet surface feel, improved sand ability and grain enhancement (Anfeuerung).
The dispersion is made without using dispersing additives, emulsifiers and defoamers and is thus highly compatible without negative influence on the coating performance.
Amide wax is used sintering industry as a lubricant.


Amide wax is recommended for use in the water-based coating systems.
Amide wax is used any of several types of amide-containing wax, such as stearamide and oleoamide.
Amide wax is commonly used as release agents.


For example, bags contain amide waxes to prevent the interior surfaces from sticking.
Amide wax is highly fragmented with the unique use of advanced powder molding process combined with modern nanotechnology.
Compared with traditional grinding mill products, Amide wax can help achieve anti-rub, abrasion resistance and slip characteristics in inks and coatings applications.


Amide wax is specifically composited micronized amide waxes.
Amide wax can improve pigment wetting and allows better degassing of powder coating based on polyester, polyester/epoxy,epoxy, acrylics and polyurethane.
Amide wax has a high affinity to metal surfaces, spreading on hot surfaces, anti blocking.


Amide wax is used in Metal die casting, lubricants, and hot melt adhesives.
Amide wax is used Rubber Industry, Releasing agent.


-ANTI-GLASSFIBRE EXPOSURE AGENT:
Amide wax is used in glass fiber reinforced PA, PBT, ABS, POM products, to prevent glass fiber from outcropping.
Amide wax is used in strengthening of PC, PPS, PPO to have a better thermal resistance.
Recommended dosage of Amide wax is 0.5 – 2%.


-ENHANCED DISPERSING AGENT:
Amide wax is used as efficient dispersing agent in high concentration color masterbatch, and specific color pigments which are difficult to disperse such as Carbon Black, Phthalocyanine Blue & Phthalocyanine Green.
Recommended dosage of Amide wax is 0.5 – 3%.


-HIGH GLOSS LUBRICANT:
Amide wax is used in plastic compounding & masterbatch; Increase fluidity and surface brightness of product for reinforced flame-retardant nylon which require higher processing temperature.
Recommended dosage of Amide wax is 0.5 – 1%.


-INORGANIC POWDER:
As coating agent with coupling agent & stearic acid, Amide wax enhances the overall performance and solve the issue of mold coking.
Recommended dosage of Amide wax is 0.5 – 2%.


-OTHER APPLICATIONS:
Amide wax is used modifying agent for road asphalt & water-proofing coating materials.
Amide wax is used as release agent for PE isolation film in tires.


-Applications include:
*Extrusion and injection of rigid or soft PVC. External lubricant.
*Rubber and PE with high molecular weight.
*Cable coverings.
*Rigid PVC extrusion. Gives good shine. Non-transparent rigid polymers.
*Anti-static.
*Hardening agent for paints, lacquers, asphalts, etc.
*In PVC used for calendering or blown film extrusion.
*Lubricant for ABS, polystyrene, acrylnitrile styrene, polystyrene and polypropylene pigment dispersion agent.



BENEFITS OF AMIDE WAX:
*Acts as a degassing agent in powder coatings
*Excellent anti-blocking and slip properties
*Good scratch resistance properties
*Increased matting
*High water repellent effect
*Improved sand-ability of wood coatings
*no influence on the transparency of polymers
*Excellent dispersion and lubricating properties in plastics applications



THINGS TO KNOW ABOUT AMIDE WAXES:
One normally distinguishes between primary and secondary types of amide waxes.
Both types are semi-synthetic waxes, i.e. the fatty acid portion is of native origin and comes from either a vegetable or an animal source.

Secondary amide waxes are essentially the synthetically manufactured EBS = ethylene-bis-stearamides, frequently also known by the name EDS = ethylene distearmides.
These secondary amide waxes are synthesised from ethylenediamine and stearic acid (usually based on animal fats, although a vegetable stearic acid is also possible upon request) in a nitrogen atmosphere, and are used as an effective and cheap process aid in many technical applications.

Our primary amide waxes, such as, among others, erucic acid amide, stearic acids amide, and oleamide are exclusively synthesised on the basis of vegetable fatty acids.
The primary and secondary amide waxes have in common that they possess good lubricating and sliding properties in many applications , act as flow improvers, or are used as dispersion additives, especially if the transparency and colour characteristics of the end product are to remain unaffected.

Typical areas of application are the plastics and rubber industries, printing ink production, paint industry, powder metallurgy, adhesives and sealants, cosmetics, leather & textiles, paper and roadbuilding.



CHARACTERISTICS AND PURPOSES OF AMIDE WAX:
Amide wax with ultrafine particle size, high melting point, outstanding grindability and smoothness, good recoatability, breathability, and anti-blocking.
Amide wax can improve the grindability when used in NC Nitroncellulose and acid cured resin those paint systems.
To ensure the fully wetting of Amide wax, the mixing time should more than 15 minutes under high-shear dispersion device.

When used in powder coating, we suggest to use the post addition method, by which can increase its charging state.
In some porous surfaces like iron casting, Amide wax acts as degassing agent.
When works together with the HAA and benzoin curing system, Amide wax can reduce the yellowish of the benzoin.
The additional amount of Amide wax is less than 1.5 %.



CONTENT AND METHODS OF USE OF AMIDE WAX:
In a variety of systems, the additional amount of Amide wax is generally between 0.5 to 3%.
Usually by a direct high-speed stirring, Amide wax can disperse in solvent-based coatings and printing inks directly.

Amide wax can be added by using varieties of grinding machines, and high-shear dispersing devices.
Should pay attention to temperature control.
Can make wax slurry with the wax at 20-30%; add Amide wax into the systems when needed, by which can save the dispersion time.



PHYSICAL and CHEMICAL PROPERTIES of AMIDE WAX:
Appearance: white micronized powder
Acid value [mg KOH/g]: 5.0 - 8.0
Drop point [°C]: 139 - 144
Particle size d50 [µm]: 5.5 - 7.5
Density (23°C) [g/cm³]: 0.99 - 1.01
Functions: Lubricants
Physical State: solid
Melting Point: 120-138 c
% Moisture: 0.2% Max
Globule Retention: Nil (100 % Passes through 150 Mesh)
Reaction with Iron Powder: No Reaction
Acid Value: Max.0.02805



FIRST AID MEASURES of AMIDE WAX:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of AMIDE WAX:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of AMIDE WAX:
-Extinguishing media:
*Suitable extinguishing media:
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of AMIDE WAX:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
required
*Body Protection:
Flame retardant antistatic protective clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of AMIDE WAX:
-Precautions for safe handling:
*Hygiene measures:
Change contaminated clothing.
Preventive skin protection recommended.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.



STABILITY and REACTIVITY of AMIDE WAX:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available
-Incompatible materials:
No data available

AMIDET N
Amidet N presents better performance in terms of thickening and foaming than Cocamide DEA.
Amidet N is liquid non-ionic surfactant with good thickening and emulsifying properties.


CAS Number: 827613-35-4
Chemical name: PEG-4 Rapeseedamide
Chemical Composition: Polyoxyethylene Rapeseedamide
INCI name: PEG-4 Rapeseedamide
Ingredient Origin: Oleochemical, Synthetic



SYNONYMS:
Amides, Rape-Oil, N-(Hydroxyethyl), Ethoxylated



Amidet N is a high concentrated liquid surfactant - PEG-4 Rapeseedamide - which shows very good solubilizing and emulsifying properties.
Amidet N presents better performance in terms of thickening and foaming than Cocamide DEA.


Amidet N is a high concentrated liquid surfactant - PEG-4 Rapeseedamide - which shows very good solubilizing and emulsifying properties.
Amidet N presents better performance in terms of thickening and foaming than Cocamide DEA.
Amidet N is a liquid non-ionic surfactant with good thickening and emulsifying properties.


Amidet N is a high concentrated liquid surfactant - PEG-4 Rapeseedamide - which shows very good solubilizing and emulsifying properties.
Amidet N presents better performance in terms of thickening and foaming than Cocamide DEA.
Amidet N is liquid non-ionic surfactant with good thickening and emulsifying properties.



USES and APPLICATIONS of AMIDET N:
Amidet N is a nitrosamine-free thickener and foam booster with emulsifying properties.
Amidet N also acts as surfactant, moisturizer and solubilizer.
Amidet N offers re-fatting skin effect, anti-corrosion and wetting power.


Amidet N is used in shampoos, shower bath, creams & lotions, hair colorants, shaving products and hand soaps.
Amidet N is used thickener and foam booster
Amidet N is used Personal Care — Beauty & Care, and Bath & Shower.


Amidet N ıs used lotions, Bath & Shower Applications, Body Wash, Bubble Bath.
Amidet N is used thickener and foam booster



PROPERTIES OF AMIDET N:
*Foam booster
*Solubilizer & Emulsifier
*Thickener



FEATURES OF AMIDET N:
*Amidet N is an effective thickener for foaming products, an emulsifier, a degreaser.
*Mild co-surfactant with good skin cleansing action, improves foaming and foam quality.
*Amidet N gives products a pleasant feeling on the skin.



FUNCTIONS OF AMIDET N:
Emulsifier, Foam Booster, Foaming Agent, Solubilizer, Solubilizer, Surfactant, Surfactant (Nonionic), Thickener, Thixotrope, Viscosity Modifier

-Cleaning Ingredients Functions
*Emulsifier,
*Foam Booster,
*Solubilizer,
*Surfactant,
*Surfactant (Nonionic)
*Thixotrope,
*Viscosity Modifier

-Cosmetic Ingredients Functions
*Emulsifier,
*Foam Booster,
*Foaming Agent,
*Solubilizer,
*Surfactant,
*Surfactant (Nonionic),
*Thickener,
*Viscosity Modifier



INDUSTRIES OF AMIDET N:
*Home Care
*Industrial & Institutional Cleaning
*Hair Care
*Skin Care
*Description



CLAIMS OF AMIDET N:
*Surfactants / Cleansing Agents > Non-ionics
*Moisturizing Agents
*Thickeners & Stabilizers
*Solubilizers
*foam booster



PROPERTIES OF AMIDET N:
*Nitroso amine free thickener and foam booster with emulsifying properties.
*Other properties : re-fatting skin effect, anticorrosion and wetting power.



CHARACTERISTIC OF AMIDET N:
*Amidet N is an effective thickener for foaming products, an emulsifier, a degreaser.
*Mild co-surfactant with good skin cleansing action, improves foaming and foam quality.
*Gives products a pleasant feeling on the skin.



PHYSICAL and CHEMICAL PROPERTIES of AMIDET N:
Product name: AMIDET N
Chemical Name: Polyoxyethylene Rapeseedamide
INCI Name: PEG-4 RAPESEEDAMIDE
Appearance: Liquid
Actual Matter (%): 95
Color (Gardner): G-4 maximum
Water, %: 6.5 – 8.5
Amide (mv/g): 1.64 – 1.75
Free amine (mv/g): 0.11 – 0.23
Viscosity (mPa.s/20°C): 500 maximum
Refraction index (nD 25): 1.4675 – 1.4705
pH (1% solution): 9.2 – 10.2
1,4-dioxane, ppm: 1 ppm maximum



FIRST AID MEASURES of AMIDET N:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available



ACCIDENTAL RELEASE MEASURES of AMIDET N:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of AMIDET N:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of AMIDET N:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of AMIDET N:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of AMIDET N:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available


AMINO ETHYL AMINO PROPYL TRIMETHOXY SILANE
Amino Ethyl Amino Propyl Trimethoxy Silane is a high functional silane with a hydrolysable methoxy group and a diamino group.
Amino Ethyl Amino Propyl Trimethoxy Silane acts as a silane coupling agent.
Amino Ethyl Amino Propyl Trimethoxy Silane improves desirable qualities such as mechanical strength, moisture or chemical resistance and electrical properties.


CAS Registry Number: 1760-24-3
EC Number: 217-164-6
MDL number: MFCD00008173
Molecular Formula: C8H22N2O3Si


Amino Ethyl Amino Propyl Trimethoxy Silane is a very representative silane coupling agent.
Amino Ethyl Amino Propyl Trimethoxy Silane is a chemical reagent used in organometallic reactions and the process of signal amplification in biomolecular labelling.


Amino Ethyl Amino Propyl Trimethoxy Silane is an amino functionalized silane coupling agent.
The individual molecules of Amino Ethyl Amino Propyl Trimethoxy Silane contain two types of reactive functional groups that are amino group and alkoxy group characterized by different reactivity thus bonding with both organic and inorganic materials.


Amino Ethyl Amino Propyl Trimethoxy Silane acts as a sort of intermediary which bonds organic materials to inorganic materials.
Amino Ethyl Amino Propyl Trimethoxy Silane improves desirable qualities such as mechanical strength, moisture or chemical resistance and electrical properties.


Amino Ethyl Amino Propyl Trimethoxy Silane improves desirable qualities such as mechanical strength, moisture or chemical resistance and electrical properties.
Amino Ethyl Amino Propyl Trimethoxy Silane is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.



USES and APPLICATIONS of AMINO ETHYL AMINO PROPYL TRIMETHOXY SILANE:
Amino Ethyl Amino Propyl Trimethoxy Silane is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Amino Ethyl Amino Propyl Trimethoxy Silane is used in the following products: adhesives and sealants and coating products.


Amino Ethyl Amino Propyl Trimethoxy Silane is extensively used in adhesives to improve adhesion.
Other release to the environment of Amino Ethyl Amino Propyl Trimethoxy Silane is likely to occur from: indoor use and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).


Release to the environment of Amino Ethyl Amino Propyl Trimethoxy Silane can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and of articles where the substances are not intended to be released and where the conditions of use do not promote release.


Other release to the environment of Amino Ethyl Amino Propyl Trimethoxy Silane is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Amino Ethyl Amino Propyl Trimethoxy Silane is used in the following products: coating products, adhesives and sealants and fillers, putties, plasters, modelling clay.
Amino Ethyl Amino Propyl Trimethoxy Silane is used in the following areas: building & construction work.
Amino Ethyl Amino Propyl Trimethoxy Silane is used for the manufacture of: machinery and vehicles, electrical, electronic and optical equipment and furniture.


Other release to the environment of Amino Ethyl Amino Propyl Trimethoxy Silane is likely to occur from: indoor use and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).
Amino Ethyl Amino Propyl Trimethoxy Silane is used in the following products: non-metal-surface treatment products, coating products, adhesives and sealants, polymers, fillers, putties, plasters, modelling clay and inks and toners.


Release to the environment of Amino Ethyl Amino Propyl Trimethoxy Silane can occur from industrial use: formulation of mixtures and formulation in materials.
Amino Ethyl Amino Propyl Trimethoxy Silane is used in the following products: non-metal-surface treatment products, polymers, adhesives and sealants, coating products and laboratory chemicals.


Amino Ethyl Amino Propyl Trimethoxy Silane has an industrial use resulting in manufacture of another substance (use of intermediates).
Amino Ethyl Amino Propyl Trimethoxy Silane is used in the following areas: building & construction work, formulation of mixtures and/or re-packaging and scientific research and development.


Amino Ethyl Amino Propyl Trimethoxy Silane is used for the manufacture of: chemicals, machinery and vehicles, mineral products (e.g. plasters, cement), rubber products, electrical, electronic and optical equipment and furniture.
Release to the environment of Amino Ethyl Amino Propyl Trimethoxy Silane can occur from industrial use: in the production of articles, as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture and as processing aid.


Release to the environment of Amino Ethyl Amino Propyl Trimethoxy Silane can occur from industrial use: manufacturing of the substance.
Amino Ethyl Amino Propyl Trimethoxy Silane improve adhesion between glass, mineral and metal surfaces and amino-reactive resins.
Amino Ethyl Amino Propyl Trimethoxy Silane improves adhesion,while maintaining good shelf stability as an additive in waterborne systems
Amino Ethyl Amino Propyl Trimethoxy Silane may be used as an additive, meeting the need of special primers in numerous bonding applications.


Amino Ethyl Amino Propyl Trimethoxy Silane is used as the equivalent of Dynasylan DAMO or Momentive Silquest A-1120.
Amino Ethyl Amino Propyl Trimethoxy Silane can erect superior adhesion to inorganic materials, for example, metals, glass, ceramics.
Amino Ethyl Amino Propyl Trimethoxy Silane can also improve adhesion to a variety of composites.
Amino Ethyl Amino Propyl Trimethoxy Silane is used Adhesives & Sealants, Chemical Synthesis, Construction Chemicals, Glass & Ceramics, Industrial Chemicals, Silicones & Silanes, Coatings.


Amino Ethyl Amino Propyl Trimethoxy Silane can be used as an adhesion promoter in paints, coating, adhesives and sealants industries.
Amino Ethyl Amino Propyl Trimethoxy Silane is typically used in one-component and two-component polysulfide sealants.
Amino Ethyl Amino Propyl Trimethoxy Silane can be used as an additive for special primers in many bonding applications.
Amino Ethyl Amino Propyl Trimethoxy Silane can be used to improve the bonding performance between organic resins and inorganic materials.


Amino Ethyl Amino Propyl Trimethoxy Silane can be used as a primer for glass and metal or a polymer additive.
Amino Ethyl Amino Propyl Trimethoxy Silane can also be used for the synthesis of textile and fabrics additives.
Amino Ethyl Amino Propyl Trimethoxy Silane uses and applications include: Coupling agent for epoxies, phenolics, melamines, nylons, PVC, acrylics, urethanes, nitrile rubbers; crosslinking agent; adhesion promoter for coatings; in food packaging adhesives.


Amino Ethyl Amino Propyl Trimethoxy Silane provides superior elongation, flexibility and spreading at the interface as a coupling agent.
Amino Ethyl Amino Propyl Trimethoxy Silane is used mainly to improve the performance of epoxy, phenolic, melamine, furan and other resin laminates.
Amino Ethyl Amino Propyl Trimethoxy Silane normally acts as a surface modifier of inorganic fillers and pigments.


Amino Ethyl Amino Propyl Trimethoxy Silane is also effective for polypropylene, polyethylene, polyacrylic acid vinegar, silicone, polyamide, polycarbonate, and Poly cyanoethylene.
Glass fiber finishing agent, Amino Ethyl Amino Propyl Trimethoxy Silane is also widely used in glass beads, silica, talc, mica, clay, fly ash and other silicon-containing substances.


Amino Ethyl Amino Propyl Trimethoxy Silane is mainly used for coupling organic polymers and inorganic, so that the two chemical bonding into a whole, in order to improve the polymer of various physical and mechanical properties, electrical properties, water resistance, aging resistance, suitable polymers for coupling are thermosetting resins, such as epoxy, phenolic, polyurethane, melamine, nitrile phenolic; Hot melt resins, such as polystyrene, polyvinyl chloride, polyamide; Elastomer Polysulfide rubber, polyurethane rubber, etc.


Amino Ethyl Amino Propyl Trimethoxy Silane can be used to couple organic polymers and inorganic materials, can be used as a glass fiber finishing agent, can be used as a crosslinking agent and curing agent for silicone rubber and silicone resin, can be used as a textile finishing agent, can also be made into amino modified silicone oil and so on.
Amino Ethyl Amino Propyl Trimethoxy Silane is useful for chemical research.


Amino Ethyl Amino Propyl Trimethoxy Silane is used coupling agent, used in rubber, plastic, glass fiber, coating, adhesive, sealant and other industries.
Amino Ethyl Amino Propyl Trimethoxy Silane is also employed as an adhesive and sealant chemical.
Further, Amino Ethyl Amino Propyl Trimethoxy Silane is used as a paint additive and coating additive.


In addition to this, Amino Ethyl Amino Propyl Trimethoxy Silane plays an important role in the production of petroleum.
Amino Ethyl Amino Propyl Trimethoxy Silane is used to couple organic polymer with inorganic material.
Amino Ethyl Amino Propyl Trimethoxy Silane can improve adhesion and water-resistance of mixed material.
Amino Ethyl Amino Propyl Trimethoxy Silane also improves anti-aging properties and various mechanical strengths.


Amino Ethyl Amino Propyl Trimethoxy Silane is a suitable polymer includes thermosetting resin, thermoplastic resin and elastomer.
Amino Ethyl Amino Propyl Trimethoxy Silane can also improve properties of epoxy and phenolic, melamine, furan resin with the effects on polypropylene, polyethylene, organic silicon, polyamide, polycarbonate and polyvinyl chloride.
Amino Ethyl Amino Propyl Trimethoxy Silane is used as glass fiber lubricant.


Amino Ethyl Amino Propyl Trimethoxy Silane extensively adapts to pearls of glass, fumed silica, talc, mica, pottery clay and clay etc.
Amino Ethyl Amino Propyl Trimethoxy Silane is used as coupling Agent, used in rubber, plastic, glass fiber, coatings, adhesives, sealants and other industries.
Amino Ethyl Amino Propyl Trimethoxy Silane is used as an organic ligand for the surface modification of silica gel to uptake heavy metal ions.


Amino Ethyl Amino Propyl Trimethoxy Silane can react with fluorinated carbon nanotubes (F-CNT) to form aminoalkylalkoxysilane functionalized carbon nanotubes.
Amino Ethyl Amino Propyl Trimethoxy Silane is a chemical reagent used in organometallic reactions and the process of signal amplification in biomolecular labelling.


-RTV Silicones and Hybrid Silane-Crosslinked Sealants
With single-double component silane-crosslinked sealant, Amino Ethyl Amino Propyl Trimethoxy Silane can improve the adhesion of many substrates, including glass, steel, aluminum and concrete.
And Amino Ethyl Amino Propyl Trimethoxy Silane can dramatically enhance the adhesion to a wide array of plastics when used in combination with SPURSM Technology for silyl urethane polymers.


-Polysulfide Sealants:
When it’s added to single-double component polysulfide sealants, Amino Ethyl Amino Propyl Trimethoxy Silane provides better adhesion to a variety of substrates, including glass, aluminum and steel.
Amino Ethyl Amino Propyl Trimethoxy Silane disperses well and can obtain cohesive split rather than interfacial split between the sealant and the substrate.
Furthermore, Amino Ethyl Amino Propyl Trimethoxy Silane can avoid using primers and it can enhance the adhesion strength between the coatings.


-Plastic sealant:
In plastic sealants treatment, Amino Ethyl Amino Propyl Trimethoxy Silane as an adhesion promoter, a replacement for polyaminoamide, can improve bonding to metal substrates.
In addition to increasing strength, the silane-modified plastic sealants have a better performance than systems those use polyaminoamide adhesion promoter.
Amino Ethyl Amino Propyl Trimethoxy Silane have a very light color and the cured compound is bubble-free.


-Additive in Phenolic and Epoxy Molding Compounds
As an additive in phenolic and epoxy molding compounds, reduces the water absorption of molded composites.
So Amino Ethyl Amino Propyl Trimethoxy Silane can effectively improve wet electrical properties, particularly at low frequencies.
High-temperature strength properties are also improved.



PROPERTIES OF AMINO ETHYL AMINO PROPYL TRIMETHOXY SILANE:
• Coupling agent
• Improved adhesion
• Increased wet and dry tensile strength and modulus to the composite
• Increased wet and dry flexural strength and modulus to the composite
• Increased wet and dry compressive strength
• Improved compatibility between inorganic filler and organic polymer



PRODUCTION METHOD OF AMINO ETHYL AMINO PROPYL TRIMETHOXY SILANE:
(1) synthesis of trimethoxysilane see γ-(glycidyl ether) propyltrimethoxysilane.
(2) synthesis of γ-(ethylenediamino) propyltrimethoxysilane obtained by addition reaction of ethylenediaminopropene and trimethoxysilane.
The addition reaction of trichlorosilane and allyl chloride is carried out under the catalysis of chloroplatinic acid, then the amination reaction is carried out with ethylenediamine, and then the product is obtained by methanol alcoholysis.

Chloropropyltrichlorosilane can also be used as a raw material to generate chloropropyltrimethoxysilane by methanol hydrolysis, and then the product N-β-aminoethyl-γ-aminopropyltrimethoxysilane is generated by Amine hydrolysis.
Among them, it is more appropriate to use steam liquid reaction for aminolysis, and the optimum conditions for aminolysis reaction are as follows: the ratio of raw material silane to ethylenediamine is 1 ∶ 3.0, and the reflux time is 3H.



PREPARATION OF AMINO ETHYL AMINO PROPYL TRIMETHOXY SILANE:
add 12mol(721.2g) of ethylenediamine to the kettle and add 1mol(198.7G) chloropropyltrimethoxysilane is pressed into the metering tank, ethylenediamine is heated to 100 r/min ° C.

Under 120 stirring, and chloropropyltrimethoxysilane in the metering tank is dropped into ethylenediamine in the reaction kettle through the dropping funnel within 4 hours, after completion of the dropwise addition, the reaction was continued at 120 ℃ for 2 hours to produce N-(β-aminoethyl) -3-aminopropyltrimethoxysilane and ethylenediamine hydrochloride, then, the temperature of the kettle is lowered to 80 ℃, and the water circulation vacuum pump is turned on at the same time.

Under the condition of-0.08MPa, ethylenediamine 8mol(480.8G) is recovered under vacuum, after lowering the temperature of the kettle to 40 ° C, the contents of the kettle were introduced into a conical sedimentation kettle for static stratification at atmospheric pressure for 4 hours.

After 4 hours of static stratification, the lower layer separated from the material in the settling kettle was 165.5G of ethylenediamine hydrochloride, and the upper layer was 273.6G of crude Amino Ethyl Amino Propyl Trimethoxy Silane, the crude upper layer was distilled at-0.1MPa to obtain 195.2g of finished Amino Ethyl Amino Propyl Trimethoxy Silane; Amino Ethyl Amino Propyl Trimethoxy Silane product GC detection content was 99.08%, product quality yield was 98.2%.



PHYSICAL and CHEMICAL PROPERTIES of AMINO ETHYL AMINO PROPYL TRIMETHOXY SILANE:
Molecular Weight: 222.36
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 9
Exact Mass: 222.13996910
Monoisotopic Mass: 222.13996910
Topological Polar Surface Area: 79.7 Ų
Heavy Atom Count: 14
Formal Charge: 0
Complexity: 134
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Formula Weight: 222.36
Boiling Point: 261-263°
Flash Point: 136°(276°F)
Density: 1.010
Refractive Index: 1.4435
Storage & Sensitivity:
Moisture Sensitive.
Air Sensitive.
Ambient temperatures.
Solubility: Miscible with toluene.
Boiling point: 261 - 263 °C (1013 hPa)
Density: 1.02 g/cm3 (20 °C)
Flash point: 136 °C
Ignition temperature: 300 °C
pH value: 10 (10 g/l, H₂O, 20 °C)
Vapor pressure: 1.5 hPa (20 °C)

Molecular Formula: C8H22N2O3Si
Molar Mass: 222.36
Density: 1.028g/mLat 25°C(lit.)
Melting Point: 0°C
Boling Point: 146°C15mm Hg(lit.)
Flash Point: 220°F
Water Solubility: REACTS
Solubility: Miscible with toluene.
Vapor Presure: 1.5 hPa (20 °C)
Appearance: Liquid
Specific Gravity: 1.01
Color: Clear colorless to light yellow
BRN: 636230
pKa: 10.11±0.19(Predicted)
PH: 10 (10g/l, H2O, 20℃)
Storage Condition: Store below +30°C.
Sensitive: 7: reacts slowly with moisture/water
Refractive Index: 20/D 1.444(lit.)
Physical state: liquid
Color: No data available
Odor: No data available

Melting point/freezing point: No data available
Initial boiling point and boiling range: 146 °C at 20 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 136 °C - DIN 51758
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available

Density: 1,028 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Color: Yellow
Density: 1.0310g/mL
Boiling Point: 114.0°C to 118.0°C (2.0 mmHg)
Flash Point: 137°C
Infrared Spectrum: Authentic
Linear Formula: (H3CO)3Si(CH2)3NH(CH2)2NH(CH2)2NH2
Refractive Index: 1.4570 to 1.4610



FIRST AID MEASURES of AMINO ETHYL AMINO PROPYL TRIMETHOXY SILANE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of AMINO ETHYL AMINO PROPYL TRIMETHOXY SILANE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up with liquid-absorbent material.
Dispose of properly.



FIRE FIGHTING MEASURES of AMINO ETHYL AMINO PROPYL TRIMETHOXY SILANE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of AMINO ETHYL AMINO PROPYL TRIMETHOXY SILANE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,2 mm
Break through time: 60 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of AMINO ETHYL AMINO PROPYL TRIMETHOXY SILANE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.



STABILITY and REACTIVITY of AMINO ETHYL AMINO PROPYL TRIMETHOXY SILANE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Incompatible materials:
No data available



SYNONYMS:
SCHEMBL189973
aminoethyl aminopropyltrimethoxysilane
3-(2-Aminoethylamino)propyltrimethoxysilane
N-β-(Aminoethyl)-γ-aminopropyl trimethoxy silane
N-(2-Aminoethyl)-γ-aminopropyltrimethoxysilane
1,2-Ethanediamine, N-[3-(trimethoxysilyl)propyl]-
Ethylenediamine, N-(3-(trimethoxysilyl)propyl)-
Silane, (3-(2-aminoethyl)aminopropyl)trimethoxy-
Silicone A-1120
N-(3-Trimethoxysilylpropyl)-ethylenediamine
Aminoethylaminopropyltrimethoxy silane
DAMO-P
Dow Corning Z-6020
Dynasylan DAMO
Dynasylan DAMO-P
Dynasylan DAMO-T
N-[3-(Trimethoxysilyl)propyl]-1,2-ethanediamine
Petrarch A0700
Prosil 3128
Union carbide A-1120
Silane, trimethoxy-[3[N-(2-aminoethyl)]aminopropyl]-
1,2-Ethanediamine, N1-[3-(trimethoxysilyl)propyl]-
A 0700
AAS-M
AP 132
en-APTAS; GF 91; KBM 603; NUCA 1120; SH 6020; Z 6020
Dow Corning product Z-6020
N-(2-Aminoethyl)-3-(trimethoxysilyl)propylamine
n1-2-aminoethyl-n2-3-trimethoxysilyl propyl ethane-1,2-diamine
3-trimethoxysilylpropyl diethylenetriamine
3-2-2-aminoethylamino ethylamino propyl-trimethoxysilane
3-trimethoxysilyl propyl diethylenetriamine
n1-3-trimethoxysilylpropyl diethylenetriamine
trimethoxysilylpropyldiethylenetriamine, 1,2-ethanediamine
n-2-aminoethyl-n'-3-trimethoxysilyl propyl
diethylenetriamino propyltrimethoxysilane
3-2-2-aminoethylamino ethylamino propyltrimethoxysilane
n-2-aminoethyl-n'-3-trimethoxysilyl propyl ethylenediamine
(2- Aminoethyl)(3-(trimethoxysilyl)propyl)amine-15N
(Trimethoxysilylpropyl)ethylenediamine-15N
(β-Aminoethyl)-γ-aminopropyltrimethoxysilane-15N
(γ- Ethylenediaminepropyl)trimethoxysilane-15N
3-(N-Aminoethyl)aminopropyltrimethoxysilane-15N
3-(Trimethoxysilyl)propylethylenediamine-15N
3- Ethylenediaminopropyltrimethoxysilane-15N
3-[N-(2-Aminoethyl)amino]propyltrimethoxysilane-15N
6-Amino-4-azahexyltrimethoxysilane-15N
A 0700-15N
A 1100-15N
A 1120-15N
A 1122-15N
A 1200-15N
A 1200 (amine)-15N
AAS-M-15N
AO 700-15N
AP 132-15N
Aminoethylaminopropyltrimethoxysilane-15N
LS 3750-15N
N-(2-Aminoethyl)-3- (trimethoxysilyl)propylamine-15N
N-(Aminoethyl)aminopropyltrimethoxysilane-15N
N- (Trimethoxysilylpropyl)ethylenediamine-15N
N-(β-Aminoethyl)-3-aminopropyltrimethoxysilane-15N
Ethylenediaminepropyl)trimethoxysilane
3-(N-Aminoethyl)aminopropyltrimethoxysilane
3-(Trimethoxysilyl)propylethylenediamine
3-Ethylenediaminopropyltrimethoxysilane
3-[N-(2-Aminoethyl)amino]propyltrimethoxysilane
DAMO
DAMO-P
DAMO-T
DB 792
DC-Z 6020
Dow Corning Z 6020
Dynasylan
DAMO Dynasylan
DAMO-P Dynasylan
DAMO-T G 91
GF 91
Gelest SIA 0591.0
Geniosil GF 91
HC 792
HD 107
Hydrosil 2776
JH 53
Aminoethyl-aminopropyl-trimethoxysilane
A 0700
AAS-M
AP 132
Dow Corning Z-6020 Silane
en-APTAS
GF 91
KBM 603
N-(3-Trimethoxysilylpropyl)-ethylenediamine
NUCA 1120
Prosil 3128
SH 6020
Silane, (3-(2-aminoethyl)aminopropyl)trimethoxy-
Silicone A-1120
Z 6020
1,2-Ethanediamine, N-(3-(trimethoxysilyl)propyl)-
1,2-Ethanediamine, N1-(3-(trimethoxysilyl)propyl)-
Ethylenediamine, N-(3-(trimethoxysilyl)propyl)-
N-(3-(Trimethoxysilyl)propyl)-1,2-ethanediamine
AEAPTMS
(Trimethoxysilylpropyl)ethylenediamine
3-[[[N-(2-Aminoethyl)amino]propyl]trimethoxy]silane
A-1120
N-(2-Aminoethyl)-3-(aminopropyl)trimethoxysilane
N-(2-Aminoethyl)-3-propylaminotrimethoxysilane
N-[(Trimethoxysilyl)propyl]ethylenediamine
N-[3-(Trimethoxysilyl)propyl]-1,2-ethylenediamine
Trimethoxy[3-[(2-aminoethyl)amino]propyl]silane
[gamma-(beta-Aminoethylaminopropyl)]trimethoxysilane
[3-[(2-Aminoethyl)amino]propyl]trimethoxysilane
[N-(beta-Aminoethyl)-gamma-aminopropyl]trimethoxysilane
N-[3-(Trimethoxysilyl)propyl]ethane-1,2-diamine
(2-Aminoethyl)(3-(trimethoxysilyl)propyl)amine
[3-(2-Aminoethylamino)propyl]trimethoxysilane
N-(2-Aminoethyl)-3-(trimethoxysilyl)propylamine
Dow Corning product Z-6020
A0700
Aas-M
sh6020
prosil3128
Prosil 3128
Petrarch A0700
Petrarch A0701
Silicone A-1120
Silane Coupling Agent A-1120
Silane Coupling Agent Kh-792
Aminoethylamino Propyltrimethoxy Silane
N-(3-Trimethoxysillylpropyl)ethylenediamine
3-(2-Aminoethylamino)propyltrimethoxysilane
3-(2-Aminoethyl)-Aminopropyltrimethoxysilane
N-[3-(Trimethoxysilyl)Propyl]Ethylenediamine
[3-(2-Aminoethyl)aminopropyl]trimethoxysilane
3-(2-aminoethyl)-aminopropyl trimethoxy silane
N-(amino-ethyl)-amino-propyl trimethoxy silane
N-(Β-Aminoethyl)- Γ-Aminopropytrimethoxysilane
N-(2-Aminoethyl)-3-Aminopropyltrimethoxysilane
N-(2-Aminoethyl)(3-aminopropyl)trimethoxysilane
N-[1-(trimethoxysilyl)propyl]ethane-1,1-diamine
N-(2-Aminoethyl)-3-(Trimethoxysilyl)Propylamine
N-[1-(trimethoxysilyl)propyl]ethane-1,2-diamine
N-[3-(trimethoxysilyl)propyl]ethane-1,2-diamine
Silane, (3-(2-aminoethyl)aminopropyl)trimethoxy-
Silane, trimethoxy-[3[N-(2-aminoethyl)]aminopropyl]-
N(beta-aminoethyl)gamma-aminopropyltrimethoxy-silane
N-Beta-(Aminoethyl)-Gamma-Aminopropyltrimethoxysilane


AMINOACETIC ACID
DESCRIPTION:
Aminoacetic acid is an amino acid that has a single hydrogen atom as its side chain.
Aminoacetic acid is the simplest stable amino acid (carbamic acid is unstable), with the chemical formula NH2‐CH2‐COOH.
Aminoacetic acid is one of the proteinogenic amino acids.

IUPAC NAME : Aminoacetic acid
CAS NUMBER : 56-40-6
EC NUMBER : 200-272-2
CHEMICAL FORMULA : C2H5NO2

Aminoacetic acid is integral to the formation of alpha-helices in secondary protein structure due to its compact form.
For the same reason, it is the most abundant amino acid in collagen triple-helices.
Aminoacetic acid is encoded by all the codons starting with GG (GGU, GGC, GGA, GGG).

Aminoacetic acid is also an inhibitory neurotransmitter – interference with its release within the spinal cord (such as during a Clostridium tetani infection) can cause spastic paralysis due to uninhibited muscle contraction.

Aminoacetic acid is the only achiral proteinogenic amino acid.
Aminoacetic acid can fit into hydrophilic or hydrophobic environments, due to its minimal side chain of only one hydrogen atom.

HISTORY AND ETYMOLOGY OF AMINOACETIC ACID
Aminoacetic acid was discovered in 1820 by French chemist Henri Braconnot when he hydrolyzed gelatin by boiling it with sulfuric acid.
He originally called it "sugar of gelatin",but French chemist Jean-Baptiste Boussingault showed in 1838 that it contained nitrogen.

In 1847 American scientist Eben Norton Horsford, then a student of the German chemist Justus von Liebig, proposed the name "glycocoll";however, the Swedish chemist Berzelius suggested the simpler current name a year later.
The name comes from the Greek word γλυκύς "sweet tasting" (which is also related to the prefixes glyco- and gluco-, as in glycoprotein and glucose).
In 1858, the French chemist Auguste Cahours determined that glycine was an amine of acetic acid.


PRODUCTION OF AMINOACETIC ACID
Although glycine can be isolated from hydrolyzed protein, this route is not used for industrial production, as it can be manufactured more conveniently by chemical synthesis.

The two main processes are amination of chloroacetic acid with ammonia, giving glycine and ammonium chloride, and the Strecker amino acid synthesis, which is the main synthetic method in the United States and Japan.


About 15 thousand tonnes are produced annually in this way.
Aminoacetic acid is also cogenerated as an impurity in the synthesis of EDTA, arising from reactions of the ammonia coproduct.

CHEMICAL REACTIONS OF AMINOACETIC ACID
Its acid–base properties are most important.

In aqueous solution, glycine is amphoteric: below pH = 2.4, it converts to the ammonium cation called glycinium.
Above about 9.6, it converts to glycinate.

Aminoacetic acid functions as a bidentate ligand for many metal ions, forming amino acid complexes.
A typical complex is Cu(glycinate)2, i.e. Cu(H2NCH2CO2)2, which exists both in cis and trans isomers.

With acid chlorides, glycine converts to the amidocarboxylic acid, such as hippuric acid and acetylglycine.

With nitrous acid, one obtains glycolic acid (van Slyke determination).
With methyl iodide, the amine becomes quaternized to give trimethylglycine, a natural product:
H3N+CH2COO−+ 3 CH3I → (CH3)3N+CH2COO−+ 3 HI

Aminoacetic acid condenses with itself to give peptides, beginning with the formation of glycylglycine:
2 H3N+CH2COO− → H3N+CH2CONHCH2COO− + H2O

Pyrolysis of glycine or glycylglycine gives 2,5-diketopiperazine, the cyclic diamide.
Aminoacetic acid forms esters with alcohols.
They are often isolated as their hydrochloride, e.g., glycine methyl ester hydrochloride.
Otherwise the free ester tends to convert to diketopiperazine.

As a bifunctional molecule, glycine reacts with many reagents.
These can be classified into N-centered and carboxylate-center reactions.

METABOLISM
BIOSYNTHESIS
Aminoacetic acid is not essential to the human diet, as it is biosynthesized in the body from the amino acid serine, which is in turn derived from 3-phosphoglycerate, but one publication made by supplements sellers seems to show that the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis.

In most organisms, the enzyme serine hydroxymethyltransferase catalyses this transformation via the cofactor pyridoxal phosphate:

serine + tetrahydrofolate → glycine + N5,N10-methylene tetrahydrofolate + H2O


In the liver of vertebrates, glycine synthesis is catalyzed by glycine synthase (also called glycine cleavage enzyme). This conversion is readily reversible:
CO2 + NH+4 + N5,N10-methylene tetrahydrofolate + NADH + H+ ⇌ Glycine + tetrahydrofolate + NAD+

In addition to being synthesized from serine, aminoacetic acid can also be derived from threonine, choline or hydroxyproline via inter-organ metabolism of the liver and kidneys.

DEGRADATION
Glycine is degraded via three pathways.
The predominant pathway in animals and plants is the reverse of the glycine synthase pathway mentioned above.
In this context, the enzyme system involved is usually called the glycine cleavage system:
Glycine + tetrahydrofolate + NAD+ ⇌ CO2 + NH+4 + N5,N10-methylene tetrahydrofolate + NADH +H+

In the second pathway, aminoacetic acid is degraded in two steps.

The first step is the reverse of glycine biosynthesis from serine with serine hydroxymethyl transferase.
Serine is then converted to pyruvate by serine dehydratase.

In the third pathway of its degradation, glycine is converted to glyoxylate by D-amino acid oxidase.
Glyoxylate is then oxidized by hepatic lactate dehydrogenase to oxalate in an NAD+-dependent reaction.

The half-life of glycine and its elimination from the body varies significantly based on dose.
In one study, the half-life varied between 0.5 and 4.0 hours.

Glycine is extremely sensitive to antibiotics which target folate, and blood glycine levels drop severely within a minute of antibiotic injections.
Some antibiotics can deplete more than 90% of glycine within a few minutes of being administered.


PHYSIOLOGICAL FUNCTION
The principal function of glycine is it acts as a precursor to proteins.
Most proteins incorporate only small quantities of glycine, a notable exception being collagen, which contains about 35% glycine due to its periodically repeated role in the formation of collagen's helix structure in conjunction with hydroxyproline.
In the genetic code, glycine is coded by all codons starting with GG, namely GGU, GGC, GGA and GGG.


AS A BIOSYNTHETIC INTERMEDIATE
In higher eukaryotes, δ-aminolevulinic acid, the key precursor to porphyrins, is biosynthesized from glycine and succinyl-CoA by the enzyme ALA synthase.
Glycine provides the central C2N subunit of all purines.

AS A NEUROTRANSMITTER
Aminoacetic acid is an inhibitory neurotransmitter in the central nervous system, especially in the spinal cord, brainstem, and retina.
When glycine receptors are activated, chloride enters the neuron via ionotropic receptors, causing an inhibitory postsynaptic potential (IPSP).
Strychnine is a strong antagonist at ionotropic glycine receptors, whereas bicuculline is a weak one.
Aminoacetic acid is a required co-agonist along with glutamate for NMDA receptors. In contrast to the inhibitory role of glycine in the spinal cord, this behaviour is facilitated at the (NMDA) glutamatergic receptors which are excitatory.
The LD50 of glycine is 7930 mg/kg in rats (oral), and it usually causes death by hyperexcitability.

USES OF AMINOACETIC ACID
In the US, glycine is typically sold in two grades: United States Pharmacopeia (“USP”), and technical grade.
USP grade sales account for approximately 80 to 85 percent of the U.S. market for glycine.

If purity greater than the USP standard is needed, for example for intravenous injections, a more expensive pharmaceutical grade glycine can be used.
Technical grade glycine, which may or may not meet USP grade standards, is sold at a lower price for use in industrial applications, e.g., as an agent in metal complexing and finishing.


ANIMAL AND HUMAN FOODS
Aminoacetic acid is not widely used in foods for its nutritional value, except in infusions.
Instead glycine's role in food chemistry is as a flavorant.
Aminoacetic acid is mildly sweet, and it counters the aftertaste of saccharine.

Aminoacetic acid also has preservative properties, perhaps owing to its complexation to metal ions.
Metal glycinate complexes, e.g. copper(II) glycinate are used as supplements for animal feeds.
The U.S. "Food and Drug Administration no longer regards glycine and its salts as generally recognized as safe for use in human food".

CHEMICAL FEEDSTOCK
Aminoacetic acid is an intermediate in the synthesis of a variety of chemical products.
Aminoacetic acid is used in the manufacture of the herbicides glyphosate, iprodione, glyphosine, imiprothrin, and eglinazine.
Aminoacetic acid is used as an intermediate of the medicine such as thiamphenicol.


LABORATORY RESEARCH OF AMINOACETIC ACID
Aminoacetic acid is a significant component of some solutions used in the SDS-PAGE method of protein analysis.
Aminoacetic acid serves as a buffering agent, maintaining pH and preventing sample damage during electrophoresis.

Aminoacetic acid is also used to remove protein-labeling antibodies from Western blot membranes to enable the probing of numerous proteins of interest from SDS-PAGE gel.
This allows more data to be drawn from the same specimen, increasing the reliability of the data, reducing the amount of sample processing, and number of samples required.
This process is known as stripping.

PRESENCE IN SPACE OF AMINOACETIC ACID
The presence of aminoacetic acid outside the earth was confirmed in 2009, based on the analysis of samples that had been taken in 2004 by the NASA spacecraft Stardust from comet Wild 2 and subsequently returned to earth.

Aminoacetic acid had previously been identified in the Murchison meteorite in 1970.
The discovery of aminoacetic acid in outer space bolstered the hypothesis of so called soft-panspermia, which claims that the "building blocks" of life are widespread throughout the universe.
In 2016, detection of aminoacetic acid within Comet 67P/Churyumov–Gerasimenko by the Rosetta spacecraft was announced.

The detection of aminoacetic acid outside the Solar System in the interstellar medium has been debated.
In 2008, the Max Planck Institute for Radio Astronomy discovered the spectral lines of a aminoacetic acid precursor (aminoacetonitrile) in the Large Molecule Heimat, a giant gas cloud near the galactic center in the constellation Sagittarius.

EVOLUTION OF AMINOACETIC ACID
Aminoacetic acid is proposed to be defined by early genetic codes.
For example, low complexity regions (in proteins), that may resemble the proto-peptides of the early genetic code are highly enriched in aminoacetic acid.

CHEMICAL AND PHYSICAL PROPERTIES OF AMINOACETIC ACID
Molecular Weight 150.13
Hydrogen Bond Donor Count 4
Hydrogen Bond Acceptor Count 6
Rotatable Bond Count 2
Exact Mass 150.06405680
Monoisotopic Mass 150.06405680
Topological Polar Surface Area 127 Ų
Heavy Atom Count 10
Formal Charge 0
Complexity 42.9
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes


SAFETY INFORMATION ABOUT AMINOACETIC ACID
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.



SYNONYMS OF AMINOACETIC ACID:
Depositor-Supplied Synonyms:
87867-94-5
glycine aminoacetic acid
SCHEMBL1493
AKOS028110004

AMINOACETIC ACID

Aminoacetic acid, commonly referred to as Aminoacetic acid, is the simplest amino acid found in nature.
Aminoacetic acid is a small, organic molecule with a molecular formula of C2H5NO2.
Aminoacetic acid is colorless, odorless, and tasteless, often occurring as a white crystalline powder.
Its chemical structure consists of a single amino group (-NH2) and a carboxyl group (-COOH) attached to the same carbon atom.

CAS Number: 56-40-6
EC Number: 200-272-2



APPLICATIONS


Aminoacetic acid is widely used in the pharmaceutical industry as a buffering agent to maintain the pH of medications and formulations.
Aminoacetic acid serves as a stabilizing agent for vaccines and certain therapeutic proteins.
In the food industry, Aminoacetic acid is utilized as a flavor enhancer, contributing to the savory taste of various dishes.
Aminoacetic acid functions as a neurotransmitter in the central nervous system, playing a role in signal transmission.

Aminoacetic acid is employed as a supplement to potentially improve sleep quality and enhance relaxation.
Aminoacetic acid is a key component of collagen, the most abundant protein in the human body, contributing to skin health and wound healing.
In cosmetics and skincare products, it is used for its moisturizing and anti-aging properties.

The production of gelatin, which is essential in the food, pharmaceutical, and photography industries, relies on Aminoacetic acid.
Aminoacetic acid is used in the manufacture of antacids to neutralize excess stomach acid.
Aminoacetic acid plays a role in the synthesis of creatine, which is essential for muscle energy metabolism.

In the pet food industry, Aminoacetic acid is added to improve palatability and provide essential nitrogen.
Aminoacetic acid is utilized as a foliar fertilizer in agriculture to supply plants with essential nutrients.
Aminoacetic acid is an important precursor in the synthesis of porphyrins, which are crucial for hemoglobin and chlorophyll.

Aminoacetic acid is employed as a reductant in various chemical reactions and can reduce metal ions in laboratory settings.
In the textile industry, it is used in dyeing processes to improve color fastness and uniformity.
Aminoacetic acid acts as a chelating agent, binding to metal ions and aiding in the removal of metal stains and scale.
Aminoacetic acid is used as a component in some skin creams and lotions to promote skin hydration.

Aminoacetic acid is employed as a dietary supplement for its potential benefits in supporting metabolic health.
In the paper and pulp industry, it is used as an additive to improve pulp bleaching processes.

Aminoacetic acid plays a role in the synthesis of purines, which are essential for DNA and RNA.
Aminoacetic acid is used in the manufacturing of specialty chemicals and as a starting material for various organic compounds.
In veterinary medicine, Aminoacetic acid can be used as a treatment for certain metabolic disorders in animals.
Aminoacetic acid serves as a stabilizing agent for certain enzymes and proteins used in biotechnology and research.

Aminoacetic acid is employed as a component in some dishwashing detergents to enhance cleaning effectiveness.
In the brewing industry, it can be used as a fining agent to clarify beer and remove impurities.

Aminoacetic acid is a crucial component in the formulation of shampoos and conditioners, contributing to hair strength and moisture retention.
Aminoacetic acid is employed in the manufacturing of toothpaste and mouthwash products to enhance the flavor and freshness of the oral care products.
In the leather industry, Aminoacetic acid is used as a tanning agent in the production of high-quality leather goods.
Aminoacetic acid is an important ingredient in dietary supplements aimed at promoting muscle growth and recovery.
Aminoacetic acid is utilized in the brewing process to control the pH of beer and prevent undesirable flavors.

In the textile industry, it serves as a dye levelling agent, ensuring uniform color distribution during dyeing.
Aminoacetic acid is used in the production of detergents to enhance the cleaning and stain-removing capabilities.

Aminoacetic acid plays a role in the synthesis of nucleic acids, contributing to the genetic material of living organisms.
Aminoacetic acid is employed in the manufacture of explosives, where it acts as a stabilizing agent.
In the production of cosmetics and skincare products, it helps maintain product stability and consistency.

Aminoacetic acid is used as a metal complexing agent in electroplating processes to improve the quality of metal coatings.
Aminoacetic acid is a key ingredient in some energy drinks and supplements for its potential performance-enhancing properties.
In the pharmaceutical industry, it is used as an excipient in tablet and capsule formulations to aid in drug delivery.

Aminoacetic acid can be used as a reducing agent in chemical analysis and laboratory experiments.
Aminoacetic acid is employed in the production of specialty chemicals, including herbicides and pesticides.
Aminoacetic acid is added to some animal feed formulations to improve nutrient absorption and overall health.

In the production of cosmetics, it can be used to regulate product pH and enhance skin hydration.
Aminoacetic acid is used in the synthesis of various chemicals, including polymers, surfactants, and plasticizers.
Aminoacetic acid plays a role in the formation of bile acids in the liver, aiding in digestion and fat absorption.
Aminoacetic acid is a component in some dietary supplements aimed at supporting cognitive function and memory.

In the manufacturing of ceramics and glass, it is employed as a flux to reduce melting temperatures.
Aminoacetic acid is used as a supplement in certain poultry diets to enhance growth and feather quality.

Aminoacetic acid is utilized as a stabilizer for enzymes used in the food and beverage industry.
In the construction industry, it can be added to cement formulations to improve concrete strength and durability.
Aminoacetic acid is employed in the production of biodegradable plastics, contributing to environmentally friendly materials.

Aminoacetic acid is a common ingredient in skincare products, including creams and serums, due to its moisturizing and skin-soothing properties.
In the textile industry, it is used as a dyeing assistant to improve the colorfastness and uniformity of dyed fabrics.

Aminoacetic acid serves as a chelating agent in water treatment processes, helping to remove heavy metal ions from wastewater.
In the agricultural sector, it can be utilized as a soil conditioner to improve soil structure and nutrient retention.

Aminoacetic acid is used in the formulation of some veterinary medicines, particularly in the treatment of livestock.
Aminoacetic acid plays a role in the synthesis of heme, a component of hemoglobin responsible for oxygen transport in red blood cells.
Aminoacetic acid is employed in the production of certain pharmaceuticals, such as antacids and analgesics.

In the pet food industry, it is added to pet treats and supplements for its potential health benefits.
Aminoacetic acid is used as a stabilizing agent for enzymes used in molecular biology and biotechnology research.
Aminoacetic acid can be incorporated into cooling bath solutions for laboratory equipment to control temperature during experiments.

In the automotive industry, Aminoacetic acid can be used as a component in engine coolants and antifreeze solutions.
Aminoacetic acid is a key ingredient in some protein-based nutritional supplements, contributing to muscle health and recovery.

Aminoacetic acid is employed in the synthesis of various chemical compounds, including pesticides and herbicides.
Aminoacetic acid can be found in some over-the-counter cough syrups and throat lozenges for its soothing properties.
In the production of ceramics and glass, it acts as a flux to lower melting temperatures and improve consistency.

Aminoacetic acid is used in the manufacturing of foaming agents for fire extinguishers and firefighting equipment.
Aminoacetic acid plays a role in the synthesis of purines and pyrimidines, essential for the formation of nucleic acids.
Aminoacetic acid is used as a buffering agent in electrophoresis, a technique for separating molecules in laboratories.
In the construction industry, it can be added to cement to enhance concrete workability and strength.

Aminoacetic acid is an ingredient in some dietary supplements marketed for stress relief and relaxation.
Aminoacetic acid is employed in the production of synthetic rubber and plastics, contributing to their elasticity.
Aminoacetic acid is utilized in the manufacturing of adhesives and sealants to improve product performance.

In the food industry, it can be used as a food additive to enhance the taste and flavor of various dishes.
Aminoacetic acid serves as a component in some formulations for leather treatments and conditioning.
Aminoacetic acid is utilized in the production of specialty chemicals, including those used in the electronics and semiconductor industries.

Aminoacetic acid is used in the cosmetic industry to create facial masks and skincare products for its skin-soothing and moisturizing properties.
In the pet care industry, it can be found in pet shampoos and grooming products to promote coat health.
Aminoacetic acid is a component in some dietary supplements aimed at supporting overall digestive health.

Aminoacetic acid serves as a buffering agent in the production of certain vaccines to maintain their stability.
In the manufacturing of photographic chemicals, Aminoacetic acid is employed as a developing agent.
Aminoacetic acid plays a role in the synthesis of various types of antibiotics and antimicrobial agents.
Aminoacetic acid is utilized in the production of specialty adhesives, including those used in the construction industry.

In the pharmaceutical field, it is used as an excipient in tablet coatings to improve drug delivery.
Aminoacetic acid can be added to poultry feed as a dietary supplement to enhance growth and feather quality.
In the production of soap and detergents, it acts as a surfactant, improving cleaning effectiveness.
Aminoacetic acid is used as a metal complexing agent in the mining industry to extract valuable metals from ores.

Aminoacetic acid plays a role in the synthesis of neurotransmitters, such as serine and glutathione, influencing brain function.
In the wine industry, it is used as a fining agent to clarify and improve the taste of wine.
Aminoacetic acid can be added to fire extinguishing solutions to enhance their firefighting effectiveness.
Aminoacetic acid serves as a reducing agent in chemical reactions, particularly in the preparation of specialty chemicals.

In the automotive sector, Aminoacetic acid is used in the formulation of some engine coolant and antifreeze products.
Aminoacetic acid is a component in certain formulations for plant-based meat substitutes to enhance flavor and texture.
In the manufacturing of ceramics, it is employed to improve the molding and firing processes.
Aminoacetic acid can be used as a pH regulator in laboratory experiments and analytical chemistry.

Aminoacetic acid is added to some body wash and shower gel formulations for its mild cleansing properties.
In the semiconductor industry, it is used as a dopant material to modify the electrical properties of silicon.
Aminoacetic acid plays a role in the synthesis of heme, which is essential for the functioning of hemoglobin.

Aminoacetic acid can be incorporated into cooling bath solutions for laboratory equipment to maintain precise temperatures.
Aminoacetic acid is utilized in the production of specialty plastics and polymers for specific industrial applications.
In the paper and pulp industry, it is used to improve the efficiency of paper bleaching processes.



DESCRIPTION


Aminoacetic acid is a common name for the chemical compound known as Aminoacetic acid.
Its chemical formula is C2H5NO2, and it is the simplest amino acid, making it an essential building block of proteins.
Aminoacetic acid is an organic compound with a single amino group (-NH2) and a carboxyl group (-COOH) attached to the same carbon atom.
Aminoacetic acid is considered a non-essential amino acid because the human body can synthesize it from other precursors, but it is still crucial for various physiological functions.

Aminoacetic acid, commonly referred to as Aminoacetic acid, is the simplest amino acid found in nature.
Aminoacetic acid is a small, organic molecule with a molecular formula of C2H5NO2.
Aminoacetic acid is colorless, odorless, and tasteless, often occurring as a white crystalline powder.
Its chemical structure consists of a single amino group (-NH2) and a carboxyl group (-COOH) attached to the same carbon atom.

Aminoacetic acid is classified as a non-essential amino acid, as the human body can synthesize it from other amino acids.
Aminoacetic acid plays a vital role as a building block for proteins, forming peptide bonds between amino acids in protein chains.
As a neurotransmitter, Aminoacetic acid serves as an inhibitory neurotransmitter in the central nervous system.

Aminoacetic acid helps regulate brain and spinal cord activity, contributing to motor control and sensory perception.
Aminoacetic acid is often used as a supplement in the form of Aminoacetic acid powder or capsules for its potential health benefits.
Aminoacetic acid is involved in the synthesis of creatine, an essential compound for energy production in muscle cells.
Aminoacetic acid is known for its sweet taste, which is used as a flavor enhancer in the food industry.

In the pharmaceutical industry, it is used as a stabilizer and buffering agent in drug formulations.
The cosmetic industry utilizes Aminoacetic acid in skincare products for its hydrating and anti-aging properties.
Aminoacetic acid is a critical component in the production of gelatin, which finds use in foods, pharmaceuticals, and photography.
Aminoacetic acid is often added to pet food to enhance palatability and as a source of nitrogen for pets.
In agriculture, it is used as a foliar fertilizer to provide plants with essential nutrients.

As a biologically important molecule, Aminoacetic acid is involved in various metabolic processes.
Aminoacetic acid aids in the synthesis of porphyrins, which are essential for hemoglobin and chlorophyll production.

Aminoacetic acid's small size and lack of a chiral center make it a versatile building block in organic chemistry.
Aminoacetic acid is used in the preparation of peptides, pharmaceuticals, and specialty chemicals.
Aminoacetic acid exhibits unique physical properties, such as high solubility in water and low toxicity.

Aminoacetic acid is considered one of the "branched-chain amino acids" and is essential for collagen formation.
In laboratory research, Aminoacetic acid is often used as a buffer to control pH in biological experiments.
Aminoacetic acid is a component of some antacid medications due to its buffering capacity.
Overall, Aminoacetic acid's diverse properties and functions make it a fundamental compound in biology, chemistry, and various industries.



PROPERTIES


Chemical Formula: C2H5NO2
Molecular Weight: 75.07 g/mol
Chemical Structure: Aminoacetic acid has a simple chemical structure with an amino group (-NH2) and a carboxyl group (-COOH) attached to the same carbon atom.
Physical State: Aminoacetic acid exists as a white, crystalline solid at room temperature.
Solubility: It is highly soluble in water and slightly soluble in ethanol and other organic solvents.
Melting Point: Aminoacetic acid has a melting point of approximately 240°C (464°F).
Boiling Point: It decomposes before reaching its boiling point.
Odor: Aminoacetic acid is odorless.
Taste: It has a sweet taste.
Color: Aminoacetic acid typically appears as a white, colorless solid.
Density: The density of Aminoacetic acid is approximately 1.6 g/cm³.
pH Level: A Aminoacetic acid solution is slightly acidic in nature with a pH around 2.34 at room temperature when fully ionized.
Hygroscopicity: Aminoacetic acid is hygroscopic, meaning it readily absorbs moisture from the air.
Stability: Aminoacetic acid is stable under normal conditions but can decompose at high temperatures.
Optical Activity: Aminoacetic acid is optically inactive because it lacks a chiral center.
Heat of Combustion: The heat of combustion of Aminoacetic acid is approximately 10.2 kJ/g.
Reactivity: Aminoacetic acid is a non-reactive compound under typical conditions.
Toxicity: Aminoacetic acid is considered non-toxic and safe for consumption.



FIRST AID


Inhalation:

If Aminoacetic acid dust or aerosol is inhaled, immediately remove the affected person from the contaminated area to a well-ventilated space.
If the person experiences difficulty breathing, seek medical attention promptly.
Provide oxygen if breathing difficulties persist.
If the individual loses consciousness, administer CPR and call for emergency medical assistance.


Skin Contact:

In case of skin contact with Aminoacetic acid, promptly remove contaminated clothing and jewelry.
Wash the affected skin area with copious amounts of water for at least 15 minutes.
Use a mild soap if available to help remove any residual Aminoacetic acid.
Seek medical attention if irritation, redness, or other adverse skin reactions occur.


Eye Contact:

If Aminoacetic acid comes into contact with the eyes, rinse the affected eye(s) immediately with gently flowing lukewarm water for at least 15 minutes. Ensure thorough flushing under the eyelids.
Hold the eyelids open during flushing to facilitate removal of the chemical.
Contact an eye specialist or seek medical attention to assess any eye damage or irritation.


Ingestion:

If Aminoacetic acid is ingested, do not induce vomiting unless instructed to do so by a healthcare professional.
Rinse the mouth with water and drink plenty of water to help dilute the chemical.
Seek immediate medical attention or contact a poison control center for guidance.
If the person experiences symptoms such as difficulty swallowing, severe abdominal pain, or altered consciousness, do not delay medical assistance.



HANDLING AND STORAGE


Handling:

Protective Equipment: When handling Aminoacetic acid, wear appropriate personal protective equipment (PPE), including safety goggles, gloves, a lab coat, and suitable footwear.

Ventilation: Work in a well-ventilated area or use local exhaust ventilation systems to minimize dust exposure.

Avoid Inhalation: Avoid breathing dust, vapors, or aerosols of Aminoacetic acid. Use a dust mask or respirator with the appropriate filter if necessary.

Prevent Skin Contact:
Prevent skin contact by wearing chemical-resistant gloves and suitable protective clothing.

Eye Protection:
Wear safety goggles or a face shield to protect against potential eye contact.

Avoid Ingestion:
Do not eat, drink, or smoke in areas where Aminoacetic acid is handled.
Wash hands thoroughly after handling.

Spills and Leaks:
Clean up spills immediately to prevent contamination.
Use appropriate absorbent materials and dispose of them properly.

Tools and Equipment:
Ensure that all laboratory or industrial tools and equipment used with Aminoacetic acid are clean and in good working order to prevent accidents or contamination.

Hygiene:
Practice good personal hygiene, including regular handwashing, after handling Aminoacetic acid.


Storage:

Storage Area:
Store Aminoacetic acid in a cool, dry, well-ventilated area away from direct sunlight and incompatible materials.

Temperature:
Maintain storage temperatures within the recommended range, typically at or below room temperature.

Containers:
Store Aminoacetic acid in tightly sealed containers, such as bottles, drums, or bags, to prevent moisture absorption and contamination.

Separation:
Store Aminoacetic acid away from strong oxidizing agents, acids, and bases, as it may react with them.

Labeling:
Clearly label storage containers with the product name, hazard information, and handling precautions.

Accessibility:
Ensure that Aminoacetic acid is stored in a location accessible only to trained and authorized personnel.

Incompatible Materials:
Avoid storing Aminoacetic acid near incompatible chemicals or substances to prevent potential reactions.



SYNONYMS


Glycocoll
Aminoethanoic acid
Aminoacetic acid
Glycolixir
Glycosthene
Aminoacetic acid Pharma brand of aminoacetic acid
Aminoacetic acid, compound with carbonic acid (1:1)
Kyselina glycinova
Aminoessigsaeure
Aminoacetic acid
Aminoethanoic acid
Aminoacetic acid gel brand of aminoacetic acid
Acetic acid, amino-
Amidocetic acid
Aminoacetate
Aminoacetic acid hydrochloride
Glycinum
Glisin
Aminoessigsaeure
Leimzucker
Monazoline
Norvaline
Trolamine
Pesticol
Aminoethanoate
Glycocollum
Glycosthen
Glicina
Aminoethanoate
Glicin
Glycocin
Glycinium
Glykokoll
Glykolsaeureamin
Glyzine
Kyselina glycinova
Glicin [Czech]
Aminoacetic acid carbonate (1:1)
Aminoacetic acid, ammonium salt
Aminoacetic acid amide
Aminoacetic acid betaine
Aminoacetic acid hydroxide
Aminoacetic acid, barium salt
Aminoacetic acid, calcium salt
Aminoacetic acid, copper(2+) salt
Aminoacetic acid, iron salt
Aminoacetic acid, lead salt
Aminoacetic acid, lithium salt
Aminoacetic acid, magnesium salt
Aminoacetic acid, manganese(2+) salt
AMINOCYCLOHEXANE
AMINOCYCLOHEXANE = CYCLOHEXYLAMINE = CHA


CAS Number: 108-91-8
EC Number: 203-629-0
MDL number: MFCD00001486
Molecular Formula: C6H13N or C6H11NH2


Aminocyclohexane appears as a clear colorless to yellow liquid with an odor of ammonia.
Aminocyclohexane's Flash point is 90 °F.
Aminocyclohexane is less dense than water.
Aminocyclohexane's vapors heavier than air.


Aminocyclohexane is a primary aliphatic amine consisting of cyclohexane carrying an amino substituent.
Aminocyclohexane is a conjugate base of a cyclohexylammonium.
Aminocyclohexane is a natural product found in Zanthoxylum asiaticum with data available.
Aminocyclohexane is an organic compound, belonging to the aliphatic amine class.


Aminocyclohexane is a colorless liquid, although, like many amines, samples are often colored due to contaminants.
Aminocyclohexane has a fishy odor and is miscible with water.
Like other amines, Aminocyclohexane is a weak base, compared to strong bases such as NaOH, but it is a stronger base than its aromatic analog, aniline.
Aminocyclohexane is used as an intermediate in synthesis of other organic compounds.


Aminocyclohexane is the precursor to sulfenamide-based reagents used as accelerators for vulcanization.
Aminocyclohexane is a building block for pharmaceuticals (e.g., mucolytics, analgesics, and bronchodilators).
The amine itself is an effective corrosion inhibitor.
The herbicide hexazinone and the anesthetic hexylcaine are derived from cyclohexylamine.


Aminocyclohexane is colorless or yellow liquid with a strong, fishy, amine-like odor.
Aminocyclohexane is Colorless to pale yellow clear liquid, no visible impurities.
Aminocyclohexane has strange odor.
Aminocyclohexane is a strong organic caustic liquid, It can form azeotrope with water at 96.40°C, miscible with a lot of organic solvents.


Aminocyclohexane is colorless or light yellow liquid. Aminocyclohexane has fishy smell.
Aminocyclohexane is strong alkaline, soluble in water, ethanol, ether, acetone, esters, hydrocarbons and other organic reagents.
Aminocyclohexane is by high thermal decomposition.
Aminocyclohexane is a colorless transparent liquid with strong fishy and ammonia odor.


Aminocyclohexane is soluble in water, with ethanol, ether, acetone, ethyl acetate, chloroform, heptane, benzene and other general organic solvents miscible.
Aminocyclohexane can volatilize with water vapor.
Aminocyclohexane can absorb carbon dioxide in the air, the formation of white crystalline carbonate.


Aminocyclohexane is an azeotrope is formed with water, with a azeotropic point of 96.4 °c and a water content of 55.8%.
Aminocyclohexane's the aqueous solution is alkaline. 0.01% concentration of aqueous solution pH = 10.5.
Aminocyclohexane appears as a clear colorless to yellow liquid with an odor of ammonia.
Aminocyclohexane's flash point is 90°F.


Aminocyclohexane is an intermediate of the herbicide cycloazinone, and also an intermediate of rubber accelerator, petroleum additive and corrosion inhibitor.
Aminocyclohexane is a food contaminant arising from its use as a boiler water additive Cyclohexylamine, also called hexahydroaniline, 1-aminocyclohexane, or aminohexahydrobenzene, is an organic chemical, an amine derived from cyclohexane.


Aminocyclohexane is a clear to yellowish liquid with fishy odor, with melting point of 17.7 °C and boiling point 134.5 °C, miscible with water.
Like other amines, Aminocyclohexane is of mildly alkaline nature, compared to strong bases such as NaOH, but it is a stronger base than its aromatic sister compound aniline, which differs only in that its ring is aromatic.


Aminocyclohexane is with flash point at 28.6 °C.
Aminocyclohexane readily absorbs through skin.
Aminocyclohexane is clear colorless to pale yellow liquid with an amine-like odor, no visible impurities.
Aminocyclohexane is a strong organic caustic liquid.


Aminocyclohexane can form azeotrope with water at 96.40 deg C. b.p.: 134.5 deg C, specific wt. (d2525 deg C) 0.8647, freezing point:-18 deg C, flash point: 90 deg F (open cup).
Aminocyclohexane is miscible with water and all common organic solvents.
Aminocyclohexane is an important organic chemical raw material.


Aminocyclohexane belongs to the class of organic compounds known as cyclohexylamines.
These are organic compounds containing a cyclohexylamine moiety, which consist of a cyclohexane ring attached to an amine group.
Aminocyclohexane, also called hexahydroaniline, 1-aminocyclohexane, or aminohexahydrobenzene, is an organic chemical, an amine derived from cyclohexane.


Aminocyclohexane is a clear to yellowish liquid with fishy odor, with melting point of −17.7 °C and boiling point 134.5 °C, miscible with water.
Like other amines, Aminocyclohexane is of mildly alkaline nature, compared to strong bases such as NaOH, but it is a stronger base than its aromatic sister compound aniline, which differs only in that its ring is aromatic.


Aminocyclohexane is a colorless organic liquid having a substituent of an amine group.
Aminocyclohexane is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Aminocyclohexane (CAS Number: 108-91-8) is an organic amine, which belongs to the aliphatic amine class that has a fishy odor and is miscible with water.


Aminocyclohexane is a colorless liquid, even though, alike various amines, the compound is often colored due to contaminants.
Aminocyclohexane contains a fishy odor and is miscible with water.
Like other amines, Aminocyclohexane is a weak base, related to strong base such as NaOH, but it is a stronger base than its aromatic analog, aniline.
Aminocyclohexane is an organic compound of the aliphatic amine group, also known as cyclohexane amine.


The chemical formula of this colorless liquid, Aminocyclohexane, is C3H13N.
However, like other amines, Aminocyclohexane may appear colored due to the presence of contaminants.
Aminocyclohexane smells like fish and can be mixed with water and other organic solvents such as alcohols, ethers, ketones and aliphatic and aromatic esters.


Aminocyclohexane was introduced in 1893 but was not used economically in the United States until 1936.
But today Aminocyclohexane is one of the most highly produced chemicals in the chemical industry and has an annual production of over one million in the United States.
According to reports published in 2016, Asia, especially China, accounts for about 65% of total global capacity.


Due to the increasing demand for nylon, the demand for Aminocyclohexane has been growing.
After China, Japan and Taiwan are also known as the largest producers of Aminocyclohexane, which accounted for 80% of total global production in 2016.
Aminocyclohexanes, like other amines, are weak bases compared to strong bases such as sodium hydroxide.


Although aniline and cyclohexyl amine both have the NH2 group and a hexagonal carbon ring, the difference in the base strength of the two substances can be attributed to their structure.
And because of this, the chemical is weaker than aniline.
Aminocyclohexane is a useful intermediate in the production of many other organic compounds.
Aminocyclohexane is a metabolite of cyclamate.


Aminocyclohexane is a building block for pharmaceuticals (e.g., mucolytics, analgesics, and bronchodilators).
Aminocyclohexane (C6H13N) belongs to the class of amine.
Aminocyclohexane is a colorless liquid with fishy odor and is readily soluble in water.
Aminocyclohexane inhibits corrosion, acts as an artificial sweetener and is used in metal working fluids.


Several industries take advantage of the uses of Aminocyclohexane, few of them are.
Aminocyclohexane molecule consists of 13 Hydrogen atom(s), 6 Carbon atom(s) and 1 Nitrogen atom(s) - a total of 20 atom(s).
The molecular weight of Aminocyclohexane is determined by the sum of the atomic weights of each constituent element multiplied by the number of atoms, which is calculated to be: 99.17412⋅gmol



USES and APPLICATIONS of AMINOCYCLOHEXANE:
Aminocyclohexane has been used as a flushing aid in the printing ink industry.
Aminocyclohexane is a useful intermediate in the production of many other organic compounds (e.g. cyclamate)
Aminocyclohexane is used For the synthesis of desulfurizers, corrosion inhibitors, vulcanization promoters, emulsifiers, antistatic agents, latex coagulants, petroleum product additives, corrosion inhibitors, fungicides, pesticides and so on.


Aminocyclohexane is the raw material of food additive sweetener: Aminocyclohexane can be used to produce cyclohexylamine sulfonate and sodium cyclamate, which is a sweetener 30 times sweeter than sucrose.
The product name is cyclamate.
Aminocyclohexane is used as a boiler feed water pH regulator.


Aminocyclohexane is mainly used for producing (Beet) molasses, cyclone, amide, nylon 6,cellulose acetate and rubber accelerator, sweetening agent, the agent for preventing corrode, emulsion, antiseptic, antistatic agent, latex cement, oil additive, germicide, pesticide and dyestuff medium, etc.
Aminocyclohexane (Glipizide EP Impurity B) is a building block for pharmaceuticals that has been used for the preparation of paromomycin analogs to be used as aminogycoside antibiotics.


Aminocyclohexane is used Chemical synthesis, Crop Protection, Explosives, Hardener and crosslinking agents for polymeres, Industrial water, Lubricants and oils, Manufacturing of diabetics, Manufacturing of dyestuffs, Manufacturing of herbicides, Manufacturing of insecticides / acaricides, Manufacturing of pharmaceutical agents, Manufacturing of pigments, Manufacturing of sweeteners, Manufacturing of textile dyestuffs, Manufacturing of textiles dyestuffs, Petroleum, Pigments, Polymer auxiliaries, Polymerisation initiator, Stabilizers for explosives, and Textile dyestuffs.


Aminocyclohexane is used raw material for producing desulfurization agent, boiler corrosion inhibitors,boiler water treatment, vulcanization accelerator, emulsifier, antistatic agent, latex coagulant, oil product additives, corrosion resistance agents, fungicides, pesticides and so on.
Aminocyclohexane is used in the manufacture of reactive dyes, softeners VS and pharmaceuticals, and can also be used in pharmaceuticals and pesticides.


Aminocyclohexane is a volatile substance, and it can easily reach the whole system after dosing.
If the pH is lower than 8.5, the effect of the Aminocyclohexane treatment is disadvantageous.
Aminocyclohexane is used as rust inhibitor, production of anti-rust paper, Clearing agent, Antifreeze, antistatic agents (Textile Auxiliaries), latex coagulants and additives for petroleum products.


Aminocyclohexane is used due to the alkalinity of cyclohexylamine aqueous solution, it can be used as an absorbent for CO2 removal and sulfur dioxide removal.
Aminocyclohexane is used in the manufacture of reactive dyes, softeners VS and medicine Crestor thionite, and so on, can also be used in medicine, pesticide.


Aminocyclohexane itself as a solvent, can be used in resin, coating, fat, paraffin oil applications.
Aminocyclohexane can also be used for the preparation of desulfurizer, rubber antioxidant, vulcanization accelerator, plastic and textile chemical additives, boiler water treatment agent, metal corrosion inhibitor, emulsifier, preservative, antistatic agent, latex coagulant, petroleum additive, bactericide, pesticide and dye intermediates.


Sulfonates of Aminocyclohexane are used in food, beverage, and medicine as an artificial flavor.
Aminocyclohexane is used in organic synthesis, plastic synthesis, also as preservatives and acid gas absorbents intermediates for the production of water treatment chemicals, artificial sweeteners, rubber processing chemicals and agrochemicals.
Aminocyclohexane is used acid gas absorbent, organic synthesis.


Aminocyclohexane is used to prepare cyclohexanol, cyclohexanone, caprolactam, cellulose acetate and Nylon 6, etc.
Aminocyclohexane is mainly used as an intermediate for organic synthesis, especially for herbicides, antioxidants&vulcanization accelerator, corrosion inhibitors, artificial sweetener etc.
Aminocyclohexane is also used to make rubber accelerator CZ and sweet-element.


Additionally, Aminocyclohexane also can be used to make cyclohexanol, cyclohexanone, emulsifying agent, preservative, antistatic agent, gelling agent, and petroleum additive.
Aminocyclohexane is used corrosion inhibitors; dye intermediate; emulsifying agent; organic syntheses; paint film solvent; petroleum additive.
Aminocyclohexane is typically used as an intermediate in synthesis for different herbicides, antioxidants and pharmaceuticals.


Aminocyclohexane is used as an intermediate in synthesis of some herbicides, antioxidants, accelerators for vulcanization, pharmaceuticals (eg. mucolytics, analgesics, and bronchodilators, corrosion inhibitors, some sweeteners (notably cyclamate), etc.
Aminocyclohexane is used in low-pressure boilers where the condensate works for a longer period of time.
Aminocyclohexane can remain along with condensate steam at various steam pressures which cannot be done with other neutralizing amines.


Aminocyclohexane is a metabolite of cyclamate and has been found to be useful in production of other organic compounds.
Aminocyclohexane is used especially for the industrial water treatment, for the production of cure accelerator, for the manufacturing of synthetic sweeteners and in a rubber industry for the production of vulcanization accelerators.
On the basis of end user demands and desires, industrial Aminocyclohexane can be utilized for various respective applications for various respective industries like agriculture, rubber, food, oil, pharma, petroleum and textile industries.


Aminocyclohexane is used by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
The primary use of Aminocyclohexane is as a corrosion inhibitor in boiler water treatment and in oil field applications (HSDB 1989).
Aminocyclohexane is also a chemical intermediate for rubber processing chemicals, dyes (acid blue 62, former use), cyclamate artificial sweeteners and herbicides and a processing agent for nylon fiber production.


Aminocyclohexane is also known as Aminohexahydrobenzene, Hexahydroaniline, Hexahydrobenzenamine, Cyclohexanamine - used in applications such as pharmaceuticals, corrosion inhibitor, oil field production, rubber chemicals, boiler water treatments.
Aminocyclohexane is used Nylon production, as a solvent, oil extractant, paint and varnish remover, dry cleaning material, as an insecticide, and as a chemical intermediate to product target molecules.


Aminocyclohexane is used in the manufacture of a number of products, including plasticizers, drycleaning soaps, insecticides, and emulsifying agents.
Aminocyclohexane is used in organic synthesis, manufacture of insecticides, plasticizers, corrosion inhibitors, rubber chemicals, dyestuffs, emulsifying agents, dry-cleaning soaps, acid gas absorbents.


Aminocyclohexane is used primarily as corrosion inhibitor and vulcanization accelerator.
Alone or mixed with other compounds, it has an anticorrosive action, for example, when used as an additive in heating oil or in the operation of steam boilers.
Aminocyclohexane functions as a hardener for epoxy resins and as a catalyst for polyurethanes.


Sodium cyclohexylsulfamate and calcium cyclohexylsulfamate (cyclamates) are important artificial sweeteners.
In polyamide polymerizations, Aminocyclohexane is employed as chain terminator to control the molecular mass.
Aminocyclohexane has application as an intermediate in synthesis of other organic compounds.
Pharmaceuticals industry suppliers buy Aminocyclohexane as a major chemical for mucolytics, analgesics, and bronchodilators.


Aminocyclohexane is the precursor to sulfenamide-based reagents employed as accelerators for vulcanization.
Aminocyclohexane is an effective corrosion inhibitor.
Aminocyclohexane is also used as certain sweeteners which are taken from this amine, particularly cyclamate.
People buy Aminocyclohexane as it is derived as herbicide from hexazinone and the anesthetic hexylcaine.


Aminocyclohexane is also used pharmaceutical, water treatment, and rubber chemical
Aminocyclohexane is used as an intermediate in synthesis of other organic compounds.
Aminocyclohexane is also used as a corrosion inhibitor and in organic synthesis.
Aminocyclohexane is used as rubber vulcanization accelerator, also used as synthetic fiber, dye, vapor phase corrosion inhibitor raw material.


Aminocyclohexane is the precursor to sulfenamide-based reagents used as accelerators for vulcanization.
Aminocyclohexane itself is an effective corrosion inhibitor.
Some sweeteners are derived from this amine, notably cyclamate.
The herbicide hexazinone is derived from Aminocyclohexane.


-Application Areas OF Aminocyclohexane:
*Agriculture
*Manufacture of Herbicides, Insecticides, Pesticides
*Catalysis & Chemicals Processing
*Chemical Synthesis Reactions
*Dyes, Pigments, Textiles
*Hardener & Cross Linking Polymers
*Industrial Water Treatment
*Polymer Auxiliaries
*Lubricants & Oils
*Petroleum
*Stabilizers for Explosives
*Polymerization Initiator


-Applications of Aminocyclohexane include the following:
*Pharmaceutical industry: Production of analgesics
*Agricultural Industries: Production of some herbicides
*Oil and gas industry:The compound mediates the synthesis of many organic compounds
*Inhibitor against corrosion and sediment
*Neutralizing raw material
*Water purifiers for boilers
*Petroleum products additive
*Cosmetics industry: as raw materials for the production of some perfumes
*Printing and dyeing industries: as a solvent
*Water and wastewater treatment
*Production of PVC adhesive



MAIN PURPOSE OF AMINOCYCLOHEXANE:
Aminocyclohexane can be used as raw material of surfactant to produce cyclohexylbenzene sulfonate, used as emulsifier and foaming agent;
perfume raw materials to produce allyl cyclohexyl propionate;
Dye raw materials to produce acid blue 62, disperse fluorescent yellow, disperse fluorescent yellow H5GL, weak acid blue BRN, Disperse Blue 6 and dye auxiliaries;

The raw material of food additive sweet material;
Cyclohexylamine can be used to produce cyclohexylamine sulfonate and sodium cyclamate, which is a sweetener 30 times higher than sucrose sweetness,
raw materials for pesticides, pesticides used in the production of fruit trees "acaraptor", herbicide Wilber and fungicides;
Additives used in the preparation of petroleum products, boiler water treatment agents and corrosion inhibitors;
raw material of rubber vulcanization accelerator to produce thiazole vulcanization accelerator CZ, which has excellent vulcanization performance and is especially suitable for SBR and FDA rubber.



KEY FEATURES AND BENEFITS of AMINOCYCLOHEXANE:
*Condensate line treatment
*Prevent of carbon dioxide corrosion
*Prevents formation of carbonic acid in boiler steam system
*Does not add to TDS of boiler water
*Completely volatile



ALTERNATIVE PARENTS of AMINOCYCLOHEXANE:
*Organopnictogen compounds
*Monoalkylamines
*Hydrocarbon derivatives



SUBSTITUENTS of AMINOCYCLOHEXANE:
*Cyclohexylamine
*Organopnictogen compound
*Hydrocarbon derivative
*Primary amine
*Primary aliphatic amine
*Amine
*Aliphatic homomonocyclic compound



PREPARATION of AMINOCYCLOHEXANE:
Cyclohexylamine is produced by two routes, the main one being the complete hydrogenation of aniline using some cobalt- or nickel-based catalysts:
C6H5NH2 + 3 H2 → C6H11NH2
It is also prepared by alkylation of ammonia using cyclohexanone.

Aminocyclohexane is obtained by catalytic reduction of aniline at high temperature and high pressure using nickel or cobalt as a catalyst.
Aminocyclohexane is also possible to obtain cyclohexanol by catalytic reduction of phenol, which is oxidized to cyclohexanone, and then aminated with ammonia to obtain cyclohexylamine.
Cyclohexylamine can be catalyzed by aniline at high temperature and high pressure (nickel or cobalt) reduction to produce cyclohexylamine product; Can also be obtained from phenol by catalytic reduction of cyclohexanol, cyclohexanone as raw materials, and ammonia amination.

Aminocyclohexane is obtained by catalytic hydrogenation of aniline, and can be divided into atmospheric pressure method and pressure method.
In addition, cyclohexylamine can be obtained by catalytic aminolysis of cyclohexane or cyclohexanol, reduction of nitrocyclohexane, and catalytic aminolysis of cyclohexanone in the presence of hydrogen.
The preparation method is obtained by using aniline as a raw material through catalytic hydrogenation.

The aniline vapor is mixed with hydrogen and then enters the catalytic reactor, and the hydrogenation reaction is carried out at 130~170 ° C. In the presence of cobalt catalyst.
After cooling, the product is distilled to obtain a finished product.



REACTIONS of AMINOCYCLOHEXANE:
Aminocyclohexane reacts with chlorine to form N,N-dichlorocyclohexylamine.
N-Cyclohexylidenecyclohexylamine reacts with chloramine to give 1-cyclohexyl-3,3-pentamethylenediaziridine, which can be hydrolyzed to give cyclohexylhydrazine .
Aminocyclohexane and formaldehyde together react with peracetic acid to give 2-cyclohexyloxaziridine.
In addition to using alkyl halides, alkyl sulfates, or alkyl phosphates, Aminocyclohexane can be alkylated with an alcohol in the presence of a catalyst, such as aluminum oxide, copper, nickel, cobalt, or platinum, or by the Leuckart – Wallach method.



PRODUCTION METHODS of AMINOCYCLOHEXANE:
Aminocyclohexane is produced by the reaction of ammonia and cyclohexanol at elevated temperature and pressure in the presence of a silica-alumina catalyst (SRI 1985).
Aminocyclohexane is also prepared by a similar process of catalytic hydrogenation of aniline at elevated temperature and pressure.
Fractionation of the product of this reaction yields CHA, aniline, and a high-boiling residue containing n-phenylcyclohexylamine and dicyclohexylamine.
In 1982, U.S. production was 4.54 metric tons and 739.3 metric tons were imported into the U.S..

There are 2 methods of producing Aminocyclohexane.
Aminocyclohexane is traditionally produced by the amination of cyclohexanol or cyclohexanone.
Aminocyclohexane suppliers used this method of production which is by the catalytic hydrogenation of aniline.
When ruthenium catalyst is in contact with the hydrogen pressure and in the presence of around one to about 8 parts by weight of ammonia, aniline is hydrogenated under an absolute pressure from about 2 to about 5 MPa at a temperature of from about 160° to about 180° C.
The yields are high and with a minimum of byproducts result.
The catalyst can be recycled.

Aminocyclohexane is produced using two methods.
These processes include:
Hydrogenation of aniline in the presence of cobalt or nickel as catalyst:
C6H5NH2 + 3H2 -> C6H11NH2



PURIFICATION METHODS of AMINOCYCLOHEXANE:
Dry the amine with CaCl2 or LiAlH4, then distil it from BaO, KOH or Na, under N2.
Also purify it by conversion to the hydrochloride (which is crystallised several times from water), then liberation of the amine with alkali and fractional distillation under N2.
The hydrochloride has m 205-207o (dioxane/EtOH).



PHYSICAL and CHEMICAL PROPERTIES of AMINOCYCLOHEXANE:
Molecular Weight: 99.17
XLogP3: 1.5
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 0
Exact Mass: 99.104799419
Monoisotopic Mass: 99.104799419
Topological Polar Surface Area: 26 Ų
Heavy Atom Count: 7
Formal Charge: 0
Complexity: 46.1
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical formula: C6H13N
Molar mass: 99.17
Appearance: clear to yellowish liquid
Odor: strong, fishy, amine odor
Density: 0.8647 g/cm3
Melting point: −17.7 °C (0.1 °F; 255.5 K)
Boiling point: 134.5 °C (274.1 °F; 407.6 K)
Solubility in water: Miscible
Solubility: very soluble in ethanol, oil
miscible in ethers, acetone, esters, alcohol, ketones
Vapor pressure: 11 mmHg (20° C)
Acidity (pKa): 10.64[3]
Refractive index (nD): 1.4565


Appearance Form: liquid
Color: light yellow
Odor: amine-like
Odor Threshold: No data available
pH: 11,5 at 100 g/l at 20 °C
Melting point/freezing point:
Melting point/range: -17 °C - lit.
Initial boiling point and boiling range: 134 °C - lit.
Flash point: 27 °C - closed cup
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 9,4 %(V)
Lower explosion limit: 1,6 %(V)
Vapor pressure: 30,66 hPa at 37,7 °C 13,33 hPa at 22 °C
Vapor density: 3,42 - (Air = 1.0)

Density. 0,867 g/cm3 at 25 °C - lit.
Relative density: 0,86 at 25 °C
Water solubility at 20 °C: completely miscible
Partition coefficient: n-octanol/water:
log Pow: 3,7 at 25 °C
Autoignition temperature: 293 °C
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 2,1 mPa.s at 20 °C
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 68,8 mN/m at 1g/l at 20 °C
Dissociation constant: 10,68 at 25 °C
Relative vapor density: 3,42 - (Air = 1.0)


Relative Density: 0.8647(25/25℃)
BP: 134.5°C
Flash Point (open): 1.4585
Melting Point: -17~-18℃
Refractive Index: 1.4585
Molecular Formula: C6H13N
Molar Mass: 99.17
Density: 0.867g/mLat 25°C(lit.)
Melting Point: -17 °C
Boling Point: 134°C(lit.)
Flash Point: 90°F
Water Solubility: MISCIBLE
Solubility: organic solvents: miscible
Vapor Presure: 10 mm Hg ( 22 °C)
Vapor Density: 3.42 (vs air)
Appearance: Liquid
Color: Clear

Exposure Limit: TLV-TWA 10 ppm (~40 mg/m3) (ACGIH).
Merck: 14,2729
BRN: 471175
pKa: 10.66(at 24℃)
PH: 11.5 (100g/l, H2O, 20℃)
Storage Condition: Store below +30°C.
Sensitive: Air Sensitive
Explosive Limit: 1.6-9.4%(V)
Refractive Index: n20/D 1.459(lit.)
Melting Point: -17.7 ℃ Boiling Point: 134.5 ℃
relative density (water = 1): 0.86
saturated vapor pressure: (kpa) 1.17(25 ℃)
refractive index: 1.4585
solubility: soluble in water, miscible in most organic solvents


Density: 0.865 g/mL
Molar volume: 114.7 mL/mol
Refractive index: 1.459
Molecular refractive power: 31.35 mL/mol
Dielectric constant: 4.43
Dipole moment: 1.31 D
Melting point: -18 °C
Boiling point: 134 °C
Vapour pressure: 1 Torr
Surface tension: 31.54 dyn/cm
Critical pressure: 4.2 atm
Solubility in water: 100 % w/w
Solubility of water: 100 % w/w
Log10 partition octanol / water: 1.49
Hildebrant solubility parameter (δ): 9.2
Hansen solubility parameter: δd: 8.5 (cal/ml)^0.5 δp: 1.5 (cal/ml)^0.5 δh: 3.2 (cal/ml)^0.5


Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.86700 to 0.86900 @ 20.00 °C.
Pounds per Gallon - (est).: 7.223 to 7.239
Refractive Index: 1.45800 to 1.46000 @ 20.00 °C.
Melting Point: -17.00 °C. @ 760.00 mm Hg
Boiling Point: 134.00 °C. @ 760.00 mm Hg
Vapor Pressure: 10.000000 mmHg @ 22.00 °C.
Vapor Density: 3.42 ( Air = 1 )
Flash Point: 81.00 °F. TCC ( 27.22 °C. )
logP (o/w): 1.490
Soluble in: water, 1000000 mg/L @ 20 °C (exp)



FIRST AID MEASURES of AMINOCYCLOHEXANE:
-Description of first-aid measures:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed
If swallowed:
Give water to drink (two glasses at most).
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of AMINOCYCLOHEXANE:
-Environmental precautions
Do not let product enter drains.
-Methods and materials for containment and cleaning up
Cover drains.
Collect, bind, and pump off spills.
Take up carefully with liquid-absorbent material.
Dispose of properly.



FIRE FIGHTING MEASURES of AMINOCYCLOHEXANE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of AMINOCYCLOHEXANE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Use tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Viton
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 120 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of AMINOCYCLOHEXANE:
-Precautions for safe handling
*Hygiene measures
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.

-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well ventilated place.
Handle under inert gas.



STABILITY and REACTIVITY of AMINOCYCLOHEXANE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



SYNONYMS:
Cyclohexanamine
Other names
Aminocyclohexane
Aminohexahydrobenzene
Hexahydroaniline
Hexahydrobenzenamine
CYCLOHEXYLAMINE
Cyclohexanamine
108-91-8
Aminocyclohexane
Hexahydroaniline
Hexahydrobenzenamine
Aminohexahydrobenzene
Cyclohexyl amine
1-Cyclohexylamine
1-Aminocyclohexane
Aniline, hexahydro-
Benzenamine, hexahydro-
Aminocylcohexane
Cyclohexylamines
cyclohexyl-amine
1-AMINO-CYCLOHEXANE
CCRIS 3645
HSDB 918
cyclohexaneamine
UNII-I6GH4W7AEG
Cyclohexylamine.HCl
I6GH4W7AEG
157973-60-9
CHEBI:15773
MFCD00001486
Cyclohexylamine
DSSTox_CID_3996
DSSTox_RID_77250
DSSTox_GSID_23996
CAS-108-91-8
HAI
EINECS 203-629-0
UN2357
BRN 0471175
cylohexylamine
cyclohexylarnine
cyclo-hexylamine
AI3-15323
cyclohexane-amine
n-cyclohexylamine
cyclohexanyl amine
Hexahydro-Aniline
monocyclohexylamine
4-Cyclohexylamine
Cyclohexylamine,(S)
Hexahydro-Benzenamine
Cyclohexanamine, 9CI
CyNH2
Cyclohexylamine
Cyclohexylamine, 99.5%
bmse000451
EC 203-629-0
CYCLOHEXYLAMINE
4-12-00-00008
BIDD:ER0290
CYCLOHEXYLAMINE
GTPL5507
CHEMBL1794762
DTXSID1023996
BDBM81970
BCP30928
Tox21_202380
Tox21_300038
STK387114
ZINC12358775
AKOS000119083
Cyclohexylamine, ReagentPlus(R), 99%
UN 2357
VS-0326
Aminocyclohexane pound>>Hexahydroaniline
NCGC00247889-01
NCGC00247889-02
NCGC00253922-01
NCGC00259929-01
AM802905
BP-21278
CAS_108-91-8
NCI60_004907
GLIPIZIDE IMPURITY B [EP IMPURITY]
Cyclohexylamine 1000 microg/mL in Methanol
Cyclohexylamine, ReagentPlus(R), >=99.9%
FT-0624217
C00571
J-002206
J-520164
Q1147539
F2190-0381
1-Aminocyclohexane
1-Cyclohexylamine
Aminocyclohexane
Aminohexahydrobenzene
Hexahydrobenzenamine
Biodur E 1
HY
Hexahydroaniline
Monocyclohexylamine
Glipizide EP Impurity B
CHA
Cyclohexylamine
cyclohexanamine
Aminocyclohexane
Hexahydroaniline
1-Cyclohexylamine
1-Aminocyclohexane
Aniline, hexahydro-
aminocyclohexane[qr]
Aminohexahydrobenzene
Benzenamine, hexahydro-
aminohexahydrobenzene[qr]
benzenamine,hexahydro-[qr]
Cyclohexanamine ChEBI
1-amino-CYCLOHEXANE
1-Aminocyclohexane
1-Cyclohexylamine
Aminocyclohexane
Aminocylcohexane
Aminohexahydrobenzene
CHA
Cyclohexanamine, 9ci
Cyclohexyl amine
Cyclohexylamine.HCL
HAI
hexahydro-Aniline
hexahydro-Benzenamine
Hexahydroaniline
Hexahydrobenzenamine
Cyclohexylamines
Aniline, hexahydro-
Benzenamine, hexahydro-
Hexahydroaniline
Hexahydrobenzenamine
1-Aminocyclohexane
1-Cyclohexylamine
Aminocyclohexane
Aminocylcohexane
Aminohexahydrobenzene
Cyclohexyl amine
HAI




AMINOETHYLETHANOLAMINE
N-(Aminoethyl)piperazine; Aminoethylpiperazine; 1-Piperazineethanamine; N-(��-Aminoethyl)piperazine; 2-Piperazinylethylamine; 1-Piperazineethylamine; 1-(2-Aminoethyl)piperazine; cas no: 140-31-8
AMINOETHYLETHANOLAMINE
AMINOETHYLETHANOLAMINE (AEEA) = N-(2-HYDROXYETHYL)ETHYLENEDIAMINE

Aminoethylethanolamine (AEEA) is a single component product, with minimal ethylenediamine impurity.
Aminoethylethanolamine is water-soluble, clear, colorless, and slightly viscous.
An ammonia-like odor is typical of Aminoethylethanolamine.

CAS Number: 111-41-1
EC Number: 203-867-5
Molecular Weight: 104.15
Molecular Formula: C4H12N2O

Aminoethylethanolamine is member from the class of Ethyleneamines and is used in a broad array of applications.
Aminoethylethanolamine or AEEA is an organic base used in the industrial manufacture of fuel and oil additives, chelating agents, and surfactants.

Aminoethylethanolamine (AEEA) is a linear molecule with primary and secondary amine groups.
Aminoethylethanolamine is a colorless liquid, with slightly higher viscosity than EDA and DETA.

Aminoethylethanolamine is used as an intermediate in the fabrication of detergents, fabric softeners, chelates, fuel additives and coatings.
Aminoethylethanolamine is a linear member of the ethyleneamines family, at room temperature Aminoethylethanolamine is a clear, colorless, oily liquid with a weak ammonia-like odor.

Aminoethylethanolamine is water soluble, and Aminoethylethanolamine dilute solutions have an alkaline pH.
Aminoethylethanolamine is building block in the manufacture of specialty corrosion inhibitors.

Aminoethylethanolamine is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 to < 10 tonnes per annum.
Aminoethylethanolamine is used at industrial sites and in manufacturing.

Aminoethylethanolamine appears as a clear colorless liquid with an ammonia-like odor.
Aminoethylethanolamine is corrosive to tissue.

Aminoethylethanolamine is combustible, but may be difficult to ignite.
Aminoethylethanolamine is less dense than water.
Aminoethylethanolamine is used to make other chemicals.

Aminoethylethanolamine is also known as AEEA.
Aminoethylethanolamine is manily used in oil additives and surfactants.

The boiling point of Aminoethylethanolamine is 243 degree celsius and melting point is -28 degree celsius.
The molar mass of Aminoethylethanolamine is 104.15 g/mol.

The chemical formula of Aminoethylethanolamine is C4H12N2O.
Aminoethylethanolamine is a single component with having very less ethylethanolamine impurity.

Aminoethylethanolamine is a very clear and colourless liquid with ammonia like odor.
The CAS number of Aminoethylethanolamine is 111-41-1.

Aminoethylethanolamine is a clear colorless liquid with an ammonia-like odor.
Aminoethylethanolamine is industrially produced in the process of the continuously hydrogenative amination of monoethylene glycol.

In the reaction mixture Aminoethylethanolamine is only yielded as a co-product of 6.8%.
The residual compounds of Aminoethylethanolamines are 3.4% of diethylene triamine, 7.0% of piperazine, 51.1% of ethylenediamine, 1.7% of diethanolamine and 30.0% of monoethanolamine.

Aminoethylethanolamine is water soluble, and Aminoethylethanolamine dilute solutions have an alkaline pH.
Aminoethylethanolamine is used in building block in the manufacture of specialty corrosion inhibitors.

Aminoethylethanolamine is member from the class of Ethyleneamines and is used in a broad array of applications.
Aminoethylethanolamine is a single-component product.

Aminoethylethanolamine is used in chelating agents, fabric softeners, lube oil & fuel additives, surfactants, textile additives, urethane chemicals.

Aminoethyl Ethanolamine is a hygroscopic liquid with a mild ammoniacal odor.
Aminoethylethanolamine is miscible with water, ethanol, and acetone, but immiscible with ether, benzene, and hexane.

Aminoethyl Ethanolamine is used as an intermediate in the manufacture of surfactants, sequestering agents, cationic textile softeners, antistatic agents, corrosion inhibitors, and insecticides.
Aminoethylethanolamine is also found in rubber products, resins, and certain medicinals.

Aminoethylethanolamine is a linear molecule with primary and secondary amine groups with chemical formula of C4H12N2O.
Aminoethylethanolamine is a hygroscopic liquid containing minimal ethylenediamine impurity.

Aminoethylethanolamine is also referred to as N-(2-Aminoethyl)ethanolamine, N-(2-Hydroxyethyl)ethylenediamine, 2-[(2-aminoethyl)amino], and N-(β-Hydroxyethyl)-Ethylenediamine.
Aminoethylethanolamine possesses mild ammonia-like odor.

Aminoethylethanolamine is a water-soluble, clear, colorless, and viscous liquid.
Aminoethylethanolamine is miscible with water, ethanol, and acetone, but immiscible with ether, benzene, and hexane.
Aminoethylethanolamine is widely used as an intermediate in the production of surfactants, sequestering agents, cationic textile softeners, antistatic agents, corrosion inhibitors, and insecticides.

Aminoethylethanolamine (CAS #000111-41- 1, 2-[(2-aminoethyl)amino]-ethanol) is a single-component product, with minimal ethylenediamine impurity.
Aminoethylethanolamine typically has an ammonia-like odor and is water-soluble, clear, colorless, and slightly viscous.

Aminoethylethanolamine is a linear molecule with a C4H12N2O the chemical formula in the primary and secondary amine groups.
Aminoethylethanolamine is a hygroscopic liquid that contains minimal ethylenediamine impurity.

Aminoethylethanolamine is often referred to as N-(2-aminoethyl)ethanolamine, N-(2 hydroxyethyl)ethylenediamine, 2-[(2-aminoethyl)amine] and N-(- -hydroxyethyl)-ethylenediamine.
Aminoethylethanolamine has a faint ammonia-like scent.

Aminoethylethanolamine is a water-soluble, clear, colorless, and viscous liquid.
Aminoethylethanolamine is miscible with ethanol, water, and acetone but is immiscible with ether, benzene, and hexane.

Aminoethylethanolamine, is a very polar compound and is difficult to analyze as Aminoethylethanolamine is often irreversibly adsorbed on most columns.

Aminoethylethanolamine reacts severely to acids.
Aminoethylethanolamine dissolve in water, ethanol, ether, hexane, acetone and benzene.
Aminoethylethanolamine absorbs the carbon dioxide in the air.

Aminoethylethanolamine is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 to < 10 tonnes per annum.
Aminoethylethanolamine is used at industrial sites and in manufacturing.

Aminoethylethanolamine Market Outlook - 2021–2030:
The global aminoethylethanolamine market size was valued at $222.5 million in 2020, and is projected to reach $357.5 million by 2030, growing at a CAGR of 4.9% from 2021 to 2030.

Aminoethylethanolamine (AEEA) belongs to ethyleneamines group.
Aminoethylethanolamine is a clear chemical compound that is soluble in water and has ammonia odor.

Increasing trends for cleanliness have surged the demand for cleaners and surfactants where aminoethylethanolamine is used as a chelating agent to reduce the deposition of minerals from surfaces during the manufacturing process.
This may act as one of the key drivers answerable for the growth of the aminoethylethanolamine market.
Moreover, the increasing demand for industrial cleaning solutions among a wide range of industries, such as oil and gas, specialty chemicals, pharmaceuticals, and others, is providing an additional push to the growth of the aminoethylethanolamine market. All these factors collectively surge the demand for aminoethylethanolamine, thereby augmenting the global market growth.

However, aminoethylethanolamine is cited as a hazardous substance by the U.S. Department of Transportation (DOT) and the National Fire Protection Association (NFPA).
Prolonged exposure to aminoethylethanolamine can cause several health-related disorders such as severe skin burns, eye damage, and irritation in the nose, throat, lungs, and asthma-like allergy.

Moreover, Aminoethylethanolamine may also cause permanent reproductive damage if exposed beyond the standard exposure limit.
This factor hampers the market growth.

On the contrary, aminoethylethanolamine possesses enhanced surface dynamic characteristics, such as flexible surface tension, enhanced surface enthalpy, entropy, and high absorption characteristics, that make Aminoethylethanolamine suitable for a wide range of applications.
Aminoethylethanolamine is increasingly used in the development of absorbents for CO2 removal applications in industries.

Moreover, characteristics, such as high absorption capacity and low energy costs, make Aminoethylethanolamine an excellent replacement for traditional tertiary amine solutions, such as methyl diethanolamine (MDEA), for absorbent manufacturing purposes.
Aminoethylethanolamine is a key factor that is anticipated to offer new opportunity in the global aminoethylethanolamine market.

The global aminoethylethanolamine market analysis is done on the basis of grade, application, and region.
Depending on grade, the market is divided into >99% and <99%.

The applications covered in the study include chelating agent, surfactants, textile additives, fabric softeners, lubricants, and others.
Region-wise, the market is analyzed across North America, Europe, Asia-Pacific, and LAMEA.

Aminoethylethanolamine market, by region:
The Asia-Pacific aminoethylethanolamine market size is projected to grow at the highest CAGR of 5.4% during the forecast period and accounted for 46.3% of aminoethylethanolamine market share in 2020.
The rise in demand for end-user industries, such as personal care, home care, and others, in China and India has surged the growth of the chemical manufacturing sectors where aminoethylethanolamine is used an intermediate for manufacturing solvents.

Aminoethylethanolamine market, by grade:
In 2020, the >99% segment was the largest revenue generator, and is anticipated to grow at a CAGR of 5.0% during the forecast period.
Proliferating demand for both household and industrial surfactants where aminoethylethanolamine with more than 99% purity is widely used as a chelating agent to prevent the deposition of minerals on metal surfaces may propel the market growth.

Aminoethylethanolamine market, by application:
By application, the lubricant segment dominated the global market in 2020, and is anticipated to grow at a CAGR of 5.0% during the forecast period.
The increasing demand for aminoethyl ethanolamine-based lubricants in the automotive sector is expected to drive the growth of the market.

For instance, according to a report published National Investment Promotion and Facilitation Agency, India’s passenger vehicle industry is expected to grow by 22%-25% in 2022.
This is projected to positively impact the growth of the aminoethyl ethanolamine market for lubricants.

Applications of Aminoethylethanolamine:
Aminoethylethanolamine is manufactured to be marketed as a chemical intermediate for the downstream manufacture of chemicals and products.
Aminoethylethanolamine has a variety of applications and is used in the production of fabric softener, textile additive, surfactants, chelating agents, lube oil and fuel additives and urethane chemicals.
Does not market aminoethylethanolamine directly for consumer use.

Other Applications:
Hardeners
Lubricant
Paint
Bath and Shower Products
Textile Auxiliary
Textile Softeners
Epoxy Coating
Fabric Softener
Urethane Catalysts
Hair care
Chelating agents
Lube oil and fuel additives
Surfactants
Textile additives
Urethane chemicals

Uses of Aminoethylethanolamine:
Aminoethylethanolamine is used as a by-product in the sectors of textile, leather and glue.
Aminoethylethanolamine is used as the raw material of surface activators.

Aminoethylethanolamine is used as a detergent admixture.
Aminoethylethanolamine is used as an admixture in shampoos and lubricants and a resin material.

Aminoethylethanolamine is used as a chemical intermediate, textile finishing compound, and additive to oils in metal cutting.
Aminoethylethanolamine is used to manufacture wet-adhesion additives for latex paints, in the manufacture of fabric softeners, fuel additives and lube oil additives.
Aminoethylethanolamine is an intermediate in the manufacture of chelating agents and surfactants.

Cleaning:
Aminoethylethanolamine is mainly used as building block for fabric softeners/surfactants, which make the textiles less harsh, “softer” or more pleasing to the touch.

Coatings:
For production of latex paints Aminoethylethanolamine acts as intermediate to form an adhesion monomer, which increases adhesion under damp conditions (wet adhesion).
Additionally, via the pendent amino and hydroxy functionalities, Aminoethylethanolamine is used in urethane systems

Fuels and Lubricants:
Aminoethylethanolamine is used in the production of chlorinated polybutene based fuel additives as a dispersant-detergent additive.

Other:
Aminoethylethanolamine is formulated as an intermediate to form polycarboxylic acids and their salts, and chelating agents.
In several additional applications Aminoethylethanolamine is used as building block for synthesis.

Uses at industrial sites
Aminoethylethanolamine is used in the following products: polymers.
Aminoethylethanolamine has an industrial use resulting in manufacture of another substance (use of intermediates).

Aminoethylethanolamine is used for the manufacture of: chemicals.
Release to the environment of Aminoethylethanolamine can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.

Industry Uses:
Corrosion inhibitor
Intermediate
Intermediates
Laboratory chemicals
Processing aids not otherwise specified
Viscosity adjustors
pH regulating agent

Consumer Uses:
Viscosity adjustors

Other Uses:
Corrosion inhibitors
Wet-strength resins
Fabric softeners
Epoxy curing agents
Polyamide resins
Fuel additives
Lube oil additives
Asphalt additives
Ore flotation
Corrosion inhibitors
Ore flotation
Asphalt
Additives
Corrosion inhibitors
Epoxy curing agents
Hydrocarbon purification
Lube oil & fuel additives
Mineral processing aids
Polyamide resins
Surfactants
Textile additives- paper wet-strength Resins
Fabric softeners
Surfactants
Coatings
Urethanes
Fuel additives
Chemical intermediates
Epoxy curing agents
Lube oils
Wet strength resins

Uses Area of Aminoethylethanolamine:
Aminoethylethanolamine is used as a by-product in the sectors of textile, leather and glue.
Aminoethylethanolamine is used as the raw material of surface activators.

Aminoethylethanolamine is used as a detergent admixture.
Aminoethylethanolamine is used as an admixture in shampoos and lubricants and a resin material.

Aminoethylethanolamines have the combined physical and chemical characteristics of both alcohols and amines in one molecule, which makes them useful intermediates in the synthesis of various target molecules for the use in many diverse areas such as pharmaceutical, urethane catalysts, coatings, personal care, products, water treatments, corrosion inhibitors, and gas treating industries.
There are 1°, 2º or 3º nitrogen atom and one hydroxyl group at least in alkanolamines.

Aminoethylethanolamine react with inorganic acids carboxylic acids to form salts, soaps, esters, or amides.
Aminoethylethanolamine are used in both water- based and solvent-based coatings to enhance the solubility, reducibility, pigment dispersing and pH stability.
They are used in cathodic electrodeposition systems and as a catalyst for chain-extend.

Aminoethylethanolamine are used to prepare surface-active soaps through reaction with fatty acids.
Surface-active soaps are used commercially as a emulsifier, lubricants, detergents, pesticides and personal care products.

Aminoethylethanolamine maintain a constant alkalinity in the boiling water flows and condensate not to form solid products which would impede line flow.
This function of Aminoethylethanolamine is applied for corrosion Inhibits.
Aminoethylethanolamine are widely employed in the preparation of water soluble cationic flocculants and ion exchange resins which adsorb solid and colloidal particles by electrostatic attraction.

Aminoethylethanolamines are used for water treatment industry.
Aminoethylethanolamine and their derivatives are widely used as intermediates for the production of active pharmaceutical ingredients such as procaine, antihistamines analgesics from N,N-dimethylethanolamine or N-methyldiethanolamine.

Aminoethylethanolamine are used to remove hydrogen sulfide (H2S) and CO2 gas from gas streams in natural and refinery gas operations.
Aminoethylethanolamine which has amine groups and hydroxyl group is used as an important intermediate for polymer condensation, pharmaceuticals, agrochemicals, paper chemicals, rubber chemicals, textile auxiliaries.
Aminoethylethanolamine is used to produce shampoo, cationic surfactants, antistatic agents and chelating agents.

Industrial Processes with risk of exposure:
Metal Machining
Soldering
Semiconductor Manufacturing
Textiles (Printing, Dyeing, or Finishing)

Benefits of Aminoethylethanolamine:
Consistent and predictable reaction products
Easily derivatized
Low vapor pressure
High viscosity
Low environmental impact
Suitable for harsh conditions
Low sensitivity
Versatile

Functions of Aminoethylethanolamine:
Raw Material,
Chemical Intermediate

History of Aminoethylethanolamine:
Air samples collected on tubes containing XAD-2 resin coated with NITC were received at SLTC along with a request for analysis for Aminoethylethanolamine.
Aminoethylethanolamine was collected on the same media used in OSHA Method 601, for diethylene triamine, so those extraction and analytical parameters were used as a starting point for Aminoethylethanolamine.

The Aminoethylethanolamine was found to readily derivatize with the NITC to form a stable derivative.
The mobile phase of 80:20 isooctane: isopropanol gave a separation for the Aminoethylethanolamine peak from interferences from the NITC.

The samples were extracted with dimethylformamide (DMF), with an extraction efficiency mean of 99.7% for the concentration range of 20.7 to 413 µg/tube.
The retention efficiency study showed no Aminoethylethanolamine on the back up section of the spiked tube or back up tube, for tubes spiked with 413.2 µg through which10-L humid air had been drawn.
The storage study showed no loss for samples stored for up to 14 days under both refrigerated and ambient conditions.

General Manufacturing Information of Aminoethylethanolamine:

Industry Processing Sectors:
Adhesive Manufacturing
All Other Basic Organic Chemical Manufacturing
Asphalt Paving, Roofing, and Coating Materials Manufacturing
Construction
Fabricated Metal Product Manufacturing
Oil and Gas Drilling, Extraction, and Support activities
Soap, Cleaning Compound, and Toilet Preparation Manufacturing

Reactivity Profile of Aminoethylethanolamine:
Aminoethylethanolamine is an amine and alcohol.
Amines are chemical bases.

They neutralize acids to form salts plus water.
These acid-base reactions are exothermic.

The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base.
Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.

Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
This chemical is hygroscopic.

Handling and Storage of Aminoethylethanolamine:
In order to maintain the high degree of purity with which Aminoethylethanolamine is manufactured and shipped, the following storage and handling considerations are recommended:

Dry Inert Gas Blanket:
Aminoethylethanolamine should be stored under a dry inert gas blanket, such as nitrogen, to minimize contamination resulting from contact with air and water.

Materials of Construction:
If slight coloration of the ethyleneamine is acceptable, storage tanks may be made of carbon steel or black iron, provided they are free of rust and mill scale.
However, if the amine is stored in such tanks, color may develop due to iron contamination.

If iron contamination cannot be tolerated, tanks constructed of types 304 or 316 stainless steel should be used. (Note: Because they are quickly corroded by amines, do not use copper, copper alloys, brass, or bronze in tanks or lines.)
Recommended storage construction for Aminoethylethanolamine is stainless steel.

Storage Temperature:
Aminoethylethanolamine (AEEA) has a pour point of -38°C.
To avoid freezing, Aminoethylethanolamine should be maintained above this temperature.
At temperatures below 5°C, viscosity becomes so high that Aminoethylethanolamine cannot be easily pumped.

Spills or Leaks:
Small spills should be covered with inorganic absorbents and disposed of properly.
Organic absorbents have been known to ignite when contaminated with amines in closed containers. Certain cellulosic materials used for spill cleanup such as wood chips or sawdust have shown reactivity with ethyleneamines and should be avoided.

Large spills should be contained and recovered.
Water may be used for clean-up purposes, but avoid disposing of the material into sewers or natural water bodies.

Disposal should be in accordance with all federal, state and local laws, regulations, and ordinances.
Ethyleneamine leaks will frequently be identified by the odor (ammoniacal) or by the formation of a white, solid, waxy substance (amine carbamates).
Inorganic absorbents or water may be used to clean up the amine waste.

Safety of Aminoethylethanolamine:
Because of the fragility of eye tissue, almost any eye contact with any ethyleneamine may cause irreparable damage, even blindness.
A single, short exposure to ethyleneamines, may cause severe skin burns, while a single, prolonged exposure may result in the material being absorbed through the skin in harmful amounts.

Exposures have caused allergic skin reactions in some individuals.
Single dose oral toxicity of ethyleneamines is low.

The principal hazards that arise in working with Aminoethylethanolamine are those associated with similar organic amines; namely, a corrosive action on skin and eyes. Precautions should be taken to prevent contact with these parts of the body such as by use of protective clothing and chemical goggles.
If contact occurs, immediately flush the exposed area with plenty of water for at least 15 minutes.

Eye exposures should be examined by a physician.
Contaminated clothing should be laundered before reuse.

If ingestion occurs, do not induce vomiting.
Have the individual drink a large amount of water (or milk, if Aminoethylethanolamine is readily available) and transport them to a medical facility immediately.

First Aid Measures of Aminoethylethanolamine:

EYES:
First check the victim for contact lenses and remove if present.
Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center.

Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN:
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing.
Gently wash all affected skin areas thoroughly with soap and water.
If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION:
IMMEDIATELY leave the contaminated area.
Take deep breaths of fresh air.

If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital.
Provide proper respiratory protection to rescuers entering an unknown atmosphere.

Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
If not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION:
DO NOT INDUCE VOMITING.
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center.

Be prepared to transport the victim to a hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body.

DO NOT INDUCE VOMITING.
IMMEDIATELY transport the victim to a hospital.

Fire Fighting Measures of Aminoethylethanolamine:

SMALL FIRE:
Dry chemical, CO2 or water spray.

LARGE FIRE:
Dry chemical, CO2, alcohol-resistant foam or water spray.
If Aminoethylethanolamine can be done safely, move undamaged containers away from the area around the fire.
Dike runoff from fire control for later disposal.

FIRE INVOLVING TANKS OR CAR/TRAILER LOADS:
Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.
Do not get water inside containers.

Cool containers with flooding quantities of water until well after fire is out.
Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
ALWAYS stay away from tanks engulfed in fire.

Accidental Release Measures of Aminoethylethanolamine:

Isolation and Evacuation:

IMMEDIATE PRECAUTIONARY MEASURE:
Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL:
Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE:
If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions.
Also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Identifiers of Aminoethylethanolamine:
CAS Number: 111-41-1
ChemSpider: 7821
ECHA InfoCard: 100.003.516
PubChem CID: 8112
UNII: RC78W6NPXT
CompTox Dashboard (EPA): DTXSID7025423
InChI:
InChI=1S/C4H12N2O/c5-1-2-6-3-4-7/h6-7H,1-5H2 check
Key: LHIJANUOQQMGNT-UHFFFAOYSA-N check
InChI=1/C4H12N2O/c5-1-2-6-3-4-7/h6-7H,1-5H2
Key: LHIJANUOQQMGNT-UHFFFAOYAR
SMILES: OCCNCCN

CAS number: 111-41-1
EINECS/ELINCS No.: 203-867-5
Molecular weight: 104.15
Molecular formula: C₄H₁₂N₂O

Chemical family: Ethylene Amines
CAS number: 111-41-1
Physical form: Liquid
Molecular Weight: 104.15
Chemical name: 2-(2-aminoethylamino)ethanol

Properties of Aminoethylethanolamine:
Chemical formula: C4H12N2O
Molar mass: 104.153 g·mol−1
Density: 1.03 g/cm3
Melting point: −28 °C (−18 °F; 245 K)
Boiling point: 243 °C (469 °F; 516 K)
Vapor pressure: 0.01 mmHg @ 20 °C ; 8.17x10−4mmHg @ 25 °C

Form: Clear liquid
Colour: colourless
Odour: ammoniacal
Odour Threshold: No data available
pH: 12 at 25 % solution
Melting point/freezing point: -38 °C at 1,013 hPa
Boiling point/boiling range: 243 °C at 1,013 hPa
Flash point: 132 °C at 1,013 hPa
Ignition temperature: > 150 °C
Flammability (solid, gas): Not applicable
Flammability (liquids): Not classified as a flammability hazard
Vapour pressure: 0.012 hPa at 20 °C
Relative vapour density: 3.6
Density: 1,030 kg/m3 at 20 °C
1,024 kg/m3 at 25 °C
1,012 kg/m3 at 40 °C
Relative density: 1.026 at 25 °C
Water solubility: soluble
Solubility in other solvents: Soluble in ethanol.
Partition coefficient: noctanol/water: log Pow: -1.46 at 25 °C
Viscosity, dynamic: 141 mPa.s at 20 °C
Explosive properties: Not explosive
Oxidizing properties: Aminoethylethanolamine or mixture is not classified as oxidizing.

Form: Viscous liquid
Color: Colorless
Odor: Ammonical
Water solubility :Miscible
Solubility in other solvents: Ethanol
pH, 25% solution: 12
Melting point/freezing point, 1013 hPa: -38 °C
Boiling point/boiling range, 1013 hPa: 243 °C
Flash point, 1013 hPa: 132 °C
Ignition temperature: > 150 °C
Vapor pressure, 20°C: 0.012 hPa
Relative vapor density, air = 1.0 3.6
Density, 25°C: 1.024 kg/m³
Relative density, 25°C: 1.026
Partition coefficient, N-octanol/water, 25°C, log Pow -1.46
Dynamic viscosity, 20°C: 141 mPa.s

Molecular Weight: 104.15
XLogP3: -1.7
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 4
Exact Mass: 104.094963011
Monoisotopic Mass: 104.094963011
Topological Polar Surface Area: 58.3 Ų
Heavy Atom Count: 7
Formal Charge: 0
Complexity: 32.9
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Aminoethylethanolamine:
Appearance (MOA 200): Clear liquid
Assay (MOA 553): ≥ 99.6 wt%
Ethylene diamine (MOA 558): ≤ 100 ppm
Color (MOA 201): ≤ 20 Hazen
Water (MOA 305): ≤ 0.2 wt%

Names of Aminoethylethanolamine:

Regulatory process names:
(2-Aminoethyl)ethanolamine
(2-Hydroxyethyl)ethylenediamine
(AEEA)
(beta-Hydroxyethyl)ethylenediamine
1-(2-(Hydroxyethyl)amino)-2-aminoethane
2-((2-Aminoethyl)amino)ethanol
2-(2-aminoethylamino)ethanol
2-(2-Aminoethylamino)ethanol
2-(2-aminoethylamino)ethanol
2-(2-aminoethylamino)ethanol; (AEEA)
Aminoethyl ethanolamine
beta-Aminoethyl-beta-hydroxyethylamine
Ethanol, 2-((2-aminoethyl)amino)-
Ethanolethylene diamine
Hydroxyethyl ethylenediamine
Monoethanolethylenediamine
N-(2-Aminoethyl)ethanolamine
N-(2-aminoethyl)ethanolamine
N-(2-Hydroxyethyl)-1,2-ethanediamine
N-(2-Hydroxyethyl)ethylenediamine
N-(beta-Hydroxyethyl)ethylenediamine
N-Aminoethyl ethanolamine
N-Hydroxyethyl-1,2-ethanediamine
N-Hydroxyethylethylenediamine

Translated names:
(AEEA) (bg)
(AEEA) (cs)
(AEEA) (da)
(AEEA) (de)
(AEEA) (el)
(AEEA) (es)
(AEEA) (et)
(AEEA) (fi)
(AEEA) (fr)
(AEEA) (hr)
(AEEA) (hu)
(AEEA) (it)
(AEEA) (lt)
(AEEA) (lv)
(AEEA) (mt)
(AEEA) (nl)
(AEEA) (no)
(AEEA) (pl)
(AEEA) (pt)
(AEEA) (ro)
(AEEA) (sk)
(AEEA) (sl)
(AEEA) (sv)
2-(2-aminoethylamino)ethanol (cs)
2-(2-aminoethylamino)ethanol (da)
2-(2-Aminoethylamino)ethanol (de)
2-(2-aminoethylamino)ethanol (mt)
2-(2-aminoethylamino)ethanol (nl)
2-(2-aminoetilamino)etanol (es)
2-(2-aminoetilamino)etanol (hr)
2-(2-aminoetilamino)etanol (hu)
2-(2-aminoetilamino)etanol (pt)
2-(2-aminoetilamino)etanol (ro)
2-(2-aminoetilamino)etanol (sl)
2-(2-aminoetilamino)etanolis (lt)
2-(2-aminoetilamino)etanols (lv)
2-(2-aminoetylamino)etanol (no)
2-(2-aminoetylamino)etanol (sv)
2-(2-Aminoetylamino)etanoli (fi)
2-(2-aminoetyloamino)etanol (pl)
2-(2-aminoetüülamino)etanool (et)
2-(2-aminoéthylamino)éthanol; (AEEA) (fr)
2-(2-amminoetilammino)etanolo (it)
2-(2-αμινο-αιθυλαμινο)αιθανόλη (el)
2-(2-аминоетиламино)етанол (bg)
2-[(2-aminoetyl)amino]etanol (sk)

CAS name:
Ethanol, 2-[(2-aminoethyl)amino]-

IUPAC names:
(AEEA)
2,2 aminoethylaminoethanol
2-(2-Aminoethylamino)-ethanol
2-(2-AMINOETHYLAMINO)ETHANOL
2-(2-Aminoethylamino)ethanol
2-(2-aminoethylamino)ethanol
2-(2-aminoethylamino)ethanol
2-[(2-aminoethyl)amino]ethan-1-ol
2-[(2-aminoethyl)amino]ethanol
2-[(2-aminoethyl)amino]ethanol
2‐[(2‐aminoethyl)amino]ethan‐1‐ol
AMINOETHYLETHANOLAMINE
Aminoethylethanolamine
Aminoethylethanolamine
Aminoethylethanolamine (AEEA) - OR30
Ethanol, 2-[(2-aminoethyl)amino]-
Unamine O - 2-(2-aminoethykamino)ethanol

Preferred IUPAC name:
2-[(2-Aminoethyl)amino]ethan-1-ol

Trade names:
AEEA
Aminoethyethanolamine
Aminoethylethanolamine
AMINOETHYLETHANOLAMINE.

Other names:
N-(2-Hydroxyethyl)ethylenediamine

Other identifiers:
111-41-1
51251-98-0
51251-98-0
603-194-00-0

Synonyms of Aminoethylethanolamine:
2-(2-Aminoethylamino)ethanol
111-41-1
N-(2-Hydroxyethyl)ethylenediamine
Aminoethylethanolamine
2-((2-Aminoethyl)amino)ethanol
N-(2-Aminoethyl)ethanolamine
N-(Hydroxyethyl)ethylenediamine
2-[(2-Aminoethyl)amino]ethanol
N-(Aminoethyl)ethanolamine
Ethanol, 2-[(2-aminoethyl)amino]-
Monoethanolethylenediamine
(2-Hydroxyethyl)ethylenediamine
(2-Aminoethyl)ethanolamine
Ethanolethylene diamine
N-Hydroxyethyl-1,2-ethanediamine
N-Hydroxyethylethylenediamine
N-(2-Hydroxyethyl)-1,2-ethanediamine
NSC 461
Ethanol, 2-((2-aminoethyl)amino)-
2-((Aminoethyl)amino)ethanol
2-[2-Aminoethylamino]ethanol
2-[(2-aminoethyl)amino]ethan-1-ol
RC78W6NPXT
1-(2-(Hydroxyethyl)amino)-2-aminoethane
.beta.-Aminoethyl-.beta.-hydroxyethylamine
NSC-461
2-(2-Hydroxyethylamino)ethylamine
N-(.beta.-Aminoethyl)ethanolamine
(.beta.-Hydroxyethyl)ethylenediamine
N-(.beta.-Hydroxyethyl)ethylenediamine
1-[2-(Hydroxyethyl)amino]-2-aminoethane
N-Aminoethylethanolamine
N-Aminoethyl ethanolamine
Hydroxyethyl ethylenediamine
CCRIS 4825
HSDB 2067
(beta-Hydroxyethyl)ethylenediamine
N-(beta-Hydroxyethyl)ethylenediamine
EINECS 203-867-5
UNII-RC78W6NPXT
beta-Aminoethyl-beta-hydroxyethylamine
BRN 0506012
n-(2-aminoethyl) ethanolamine
AI3-15368
aminoethylethanolamin
N-(2-HYDROXYETHYL)-ETHYLENEDIAMINE
1-Aminoethyl ethanolamine
EC 203-867-5
(Hydroxyethyl)ethylenediamine
WLN: Z2M2Q
SCHEMBL18854
4-04-00-01558 (Beilstein Handbook Reference)
BIDD:GT0276
N-(2-aminoethyl)-ethanolamine
N-hydroxyethyl ethylene diamine
2-(2-aminoethylamino) ethanol
2-(2-aminoethylamino)-ethanol
NSC461
SCHEMBL2787111
2-Amino-2'-hydroxydiethylamine
CHEMBL3186403
DTXSID7025423
N-(2-hydroxyethyl)ethylendiamine
N-(beta-aminoethyl) ethanolamine
2-[(2-aminoethyl)amino]-ethanol
N-(2-hydroxy ethyl)ethylenediamine
N-(2'-Hydroxyethyl)ethylenediamine
ZINC6021259
AMINOETHYLETHANOLAMINE [INCI]
N-.beta.-Hydroxyethylethylenediamine
Tox21_200209
BBL027690
MFCD00008170
N-(2-hydroxy ethyl) ethylenediamine
STK802366
AMINOETHYL ETHANOLAMINE [HSDB]
N-(beta-hydroxyethyl)-ethylenediamine
AKOS009156720
HYDROXYETHYLETHYLENEDIAMINE, N-
CS-W011299
N-(2-Hydroxyethyl)ethylenediamine, 99%
NCGC00248562-01
NCGC00257763-01
CAS-111-41-1
VS-08576
DB-040972
A0299
FT-0629139
D77720
EN300-126824
A935986
Q209289
Q-200137
F0001-0240
N-(2-Aminoethyl)ethanolamine
(2-HYDROXYETHYL)ETHYLENEDIAMINE
(β-Hydroxyethyl)ethylenediamine
111-41-1 [RN]
2-(2-Aminoethylamino)ethanol
2-[(2-Aminoethyl)amino]ethanol [ACD/IUPAC Name]
2-[(2-Aminoethyl)amino]ethanol [German] [ACD/IUPAC Name]
2-[(2-Aminoéthyl)amino]éthanol [French] [ACD/IUPAC Name]
203-867-5 [EINECS]
Aminoethylethanolamin [German]
Aminoethylethanolamine [Wiki]
Ethanol, 2-((2-aminoethyl)amino)-
Ethanol, 2-[(2-aminoethyl)amino]- [ACD/Index Name]
KJ6300000
MFCD00008170 [MDL number]
N-(2-hydroxyethyl)ethylenediamine
N-(2'-Hydroxyethyl)ethylenediamine
N-(Hydroxyethyl)ethylenediamine
N-(β-Aminoethyl)ethanolamine
N-(β-Hydroxyethyl)ethylenediamine
N-Aminoethyl ethanolamine
N-Hydroxyethyl-1,2-ethanediamine
RC78W6NPXT
β-Aminoethyl-β-hydroxyethylamine
(2-AMINOETHYL)ETHANOLAMINE
(β-Hydroxyethyl)ethylenediamine
1-(2-(Hydroxyethyl)amino)-2-aminoethane
1-[2-(Hydroxyethyl)amino]-2-aminoethane
1246819-88-4 [RN]
147770-06-7 [RN]
1-Aminoethyl ethanolamine
2-​(2-​aminoethylamino)​ethanol
2-((2-aminoethyl)amino)ethanol
2-((Aminoethyl)amino)ethanol
2-(2-Amino-ethylamino)-ethanol
2-(2-AMINOETHYLAMINO)ETHANOL-D4
2-(2-Hydroxyethylamino)ethylamine
2-[(2-aminoethyl)amino]ethan-1-ol
2-[2-Aminoethylamino]ethanol
20261-60-3 [RN]
263-177-5 [EINECS]
263-179-6 [EINECS]
2-Amino-2'-hydroxydiethylamine
2-hydroxyethylethylenediamine
4-04-00-01514 [Beilstein]
51251-98-0 [RN]
59219-56-6 [RN]
61791-44-4 [RN]
61791-46-6 [RN]
66085-61-8 [RN]
8033-73-6 [RN]
Aminoethyl ethanolamine
Aminoethylethanolamin
Ethanolethylene diamine
ethylenediamine, N-(2-hydroxyethyl)-
H2dea
Hydroxyethyl ethylenediamine
hydroxyethylethylenediamine
Jsp000857
N-(2-Aminoethyl) ethanolamine
N-(2-Hydroxyethyl)-1,2-ethanediamine
N-(2-HYDROXYETHYL)ETHANE DIAMINE
N-(2-hydroxyethyl)-ethylenediamine
N-(Aminoethyl)ethanolamine
N-(β-Hydroxyethyl)ethylenediamine
N,N'-Iminodiethanol
N-AMINOETHYLETHANOLAMINE
N-β-Hydroxyethylethylenediamine
UNII:RC78W6NPXT
UNII-RC78W6NPXT
VS-08576
WLN: Z2M2Q
β-Aminoethyl-β-hydroxyethylamine

MeSH Entry Terms of Aminoethylethanolamine:
aminoethylethanolamine
monoethanol ethylenediamine
N-(2-aminoethyl)ethanolamine
N-(2-hydroxyethyl)ethylenediamine
N-(2-hydroxyethyl)ethylenediamine dihydrochloride
N-(2-hydroxyethyl)ethylenediamine monohydrochloride
N-(2-hydroxyethyl)ethylenediamine sodium salt
AMINOETHYLPIPERAZINE
Aminoethylpiperazine is a combustible and corrosive aliphatic amine.
Aminoethylpiperazine is a colorless to light yellow liquid.
Aminoethylpiperazine used for studying corrosion inhibition.

CAS: 140-31-8
MF: C6H15N3
MW: 129.2
EINECS: 205-411-0

An amine combining a primary, secondary, and ter- tiary amine in one molecule.
A colorless liquid with a faint fishlike odor.
Flash point 199°F.
Corrosive to tissue.
Toxic oxides of nitrogen are produced by combustion.
Aminoethylpiperazine is a derivative of piperazine.
This ethyleneamine contains three nitrogen atoms; one primary, one secondary and one tertiary.

Aminoethylpiperazine is a corrosive organic liquid and can cause second or third degree burns.
Aminoethylpiperazine can also cause pulmonary edema as a result of inhalation.
Aminoethylpiperazine is REACH and TSCA registered.
Aminoethylpiperazine, also known as N-aminoethyl piperazine, is an organic synthesis intermediate and pharmaceutical intermediate.
Aminoethylpiperazine can be used as an important fine chemical with high added value and is widely used in polyurethane, plastic, pesticide and electroplating industries.

Aminoethylpiperazine Chemical Properties
Melting point: -19 °C
Boiling point: 218-222 °C(lit.)
Density: 0.985 g/mL at 25 °C(lit.)
Vapor density: 4.4 (vs air)
Vapor pressure: 0.05 mm Hg ( 20 °C)
Refractive index: n20/D 1.500
Fp: 200 °F
Storage temp.: Store below +30°C.
Solubility: >1000g/l
Form: Liquid
pka: 10.11±0.10(Predicted)
Color: Clear colorless to slightly yellow
PH: 12 (100g/l, H2O, 20℃)
Explosive limit: 2.1-10.5%(V)
Water Solubility: soluble
Sensitive: Air Sensitive
BRN: 104363
Stability: Stable. Flammable. Incompatible with acids, acid anhydrides, acid chlorides, strong oxidizing agents, chloroformates.
LogP: -1.48 at 20℃
CAS DataBase Reference: 140-31-8(CAS DataBase Reference)
NIST Chemistry Reference: Aminoethylpiperazine (140-31-8)
EPA Substance Registry System: Aminoethylpiperazine (140-31-8)

Uses
Aminoethylpiperazine is utilized in a variety of reactions for studying corrosion inhibition, biological activity and metal ligand effects on catalysis.
Aminoethylpiperazine is used for epoxy curing, surface activation, and as an asphalt additive.
Aminoethylpiperazine is used in lube oil and fuel additives, mineral processing aids, polyamide resins, urethane chemicals, wet strength resins.
Aminoethylpiperazine uses include inhibition of corrosion, surface activation, and as an asphalt additive.
As Aminoethylpiperazine is alkaline and carbon dioxide is weakly acidic, it has been researched as a carbon dioxide sequestrant.
Aminoethylpiperazine is part of ongoing research in Carbon capture and storage.

Reactivity Profile
Aminoethylpiperazine neutralizes acids to form salts plus water in exothermic reactions.
May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.

Production
Ethylene dichloride is reacted with ammonia as a main method of production.
This process produces various ethylene amines which can then be purified by distillation.
These include ethylenediamine, diethylenetriamine, triethylenetetramine, tetraethylenepentamine, other higher homologues and Aminoethylpiperazine
Aminoethylpiperazine is also manufactured by reacting ethylenediamine or ethanolamine/ammonia mixtures over a catalyst.

Synonyms
140-31-8
N-Aminoethylpiperazine
N-(2-Aminoethyl)piperazine
1-(2-Aminoethyl)piperazine
2-(piperazin-1-yl)ethanamine
1-Piperazineethanamine
2-piperazin-1-ylethanamine
Aminoethylpiperazine
Piperazineethanamine
1-Piperazineethylamine
1-AMINOETHYLPIPERAZINE
Piperazine, 1-(2-aminoethyl)-
2-Piperazin-1-ylethylamine
USAF DO-46
2-Piperazinylethylamine
NSC 38968
2-(1-Piperazinyl)ethylamine
N-(beta-Aminoethyl)piperazine
CCRIS 6678
HSDB 5630
N-(Aminoethyl)piperazine
EINECS 205-411-0
UN2815
4-(2-aminoethyl)piperazine
BRN 0104363
AI3-52274
MLS000736991
DTXSID2021997
UNII-I86052F9F6
N-(.beta.-Aminoethyl)piperazine
2-(piperazin-1-yl)ethan-1-amine
NSC-38968
I86052F9F6
EC 205-411-0
1-[2-Aminoethyl]piperazine
5-23-01-00257 (Beilstein Handbook Reference)
DTXCID401997
28631-79-0
AEP
CAS-140-31-8
Ancamine AEP
aminoethyl piperazine
1-Piperazinaetanamina
1-Piperazinaetilamina
2-aminoethylpiperazine
2-Piperaziniletilamina
Epikure 3202
n-aminoethyl piperazine
AEP (CHRIS Code)
N-AEP
Aminoethylpiperazine, n-
N-2-aminoethylpiperazine
1-(2-aminoetil) piperazina
2-piperazin-1-yl-ethylamine
4-(2-aminoetil) piperazina
n-(2-aminoethyl) piperazine
SCHEMBL17210
2-(1-Piperazinyl)ethanamine
N-(2-amino ethyl)piperazine
N-(2-aminoethyl)-piperazine
WLN: T6M DNTJ D2Z
1-(2-aminoethyl) piperazine
1-(2-aminoethyl)-piperazine
2-(1-piperazinil) etanamina
2-(1-piperazinil) etilamina
1-(beta-Aminoethyl)piperazine
N-(beta-aminoethyl)-piperazine
1-(2-aminoethyl)- piperazine
CHEMBL209790
D.E.H. 39 (Salt/Mix)
2-(1-Piperazinyl)ethanamine #
Piperazina, 1-(2-aminoetil)-
PIPERAZINEETHANAMINE, 1-
N-(2-AMINOETHYL)PYPERAZINE
1-(. Beta.-Aminoetil) piperazina
1-(2-Aminoethyl)piperazine, 99%
NSC38968
Tox21_202230
Tox21_302922
BBL011596
MFCD00005971
NA2815
STL163329
AKOS000118842
AM81364
LF-0556
UN 2815
NCGC00249192-01
NCGC00256327-01
NCGC00259779-01
SMR000393948
N-(2-AMINOETHYL)PIPERAZINE [HSDB]
LS-110237
A0304
FT-0629105
Piperazine 1-(2-aminoethyl)-(6CI7CI8CI)
EN300-17952
N-Aminoethylpiperazine [UN2815] [Corrosive]
N-Aminoethylpiperazine [UN2815] [Corrosive]
Q3887815
W-109074
Z57127897
F2191-0297
InChI=1/C6H15N3/c7-1-4-9-5-2-8-3-6-9/h8H,1-7H
1-(2-aminoethyl)piperazine; N-(2-Aminoethyl)piperazine; 4-(2-Aminoethyl)piperazine
AMINOETHYLPIPERAZINE (AEP)
2-(2-Aminoethylamino)-Ethanol; N-hydroxyethyl-1,2-ethanediamine; N-hydroxyethylethylenediamine; N-(2-Hydroxyethyl)ethylenediamine; 2-((aminoethyl)amino)ethanol; N-aminoethylethanolamine; cas no: 111-41-1
AMINOETILETANOLAMIN-(AEEA)
EC / List no.: 217-707-7; CAS no.: 1937-19-5; Mol. formula: CH7ClN4Nom INCI : AMINOGUANIDINE HCL; 240-295-5 [EINECS]; 3909606; Aminoguanidine hydrochloride; Guanylhydrazine hydrochloride; Hydrazincarboximidamidhydrochlorid (1:1) [German] ; Hydrazinecarboximidamide hydrochloride; Hydrazinecarboximidamide, chlorhydrate (1:1) [French] ; Hydrazinecarboximidamide, hydrochloride (1:1) ; Pimagedine hydrochloride; (Diaminomethylene)hydraziniumchloride; (diaminomethylideneamino)azanium chloride; [1937-19-5]; 1-aminoguanidine hydrochloride; 2-aminoguanidine;hydrochloride; 2-aminoguanidine;hydron;chloride; 2-ammonioguanidine chloride; 2-azaniumylguanidine chloride; Carbazamidine monohydrochloride; 1-aminoguanidine hydrochloride; Aminoguanidine Hydrochloride; hydrazinecarboximidamide hydrochloride; hydrazinecarboximidamide hydrochloride; N-aminoguanidine hydrochloride; Aminoguanadine hydrochloride; Aminoguanadine hydrochloride 98%; Aminoguanidine (hydrochloride); Aminoguanidine HCl; aminoguanidine hydrochloride, 98%; Aminoguanidine monohydrochloride; AminoguanidineHydrochloride; Aminoguanidinhydrochlorid; Aminoguanidinium chloride; carbazamidine hydrochloride; carbazamidine monohydrochloride; carbonohydrazonic diamide hydrochloride; CST-8 |; Guanidine, amino-, hydrochloride; hydrazinecarboximidamide hcl(1:x); Hydrazinecarboximidamide hydrochloride; Hydrazinecarboximidamide hydrochloride(1:x); hydrazinecarboximidamide hydrochloridehydrochloride; Hydrazinecarboximidamide(9CI); Hydrazinecarboximidamide, hydrochloride; Hydrazinecarboximidamide, hydrochloride; Hydrazinecarboximidamide, monohydrochloride; Hydrazinecarboximidamide,hydrochloride (9CI); HYDROGEN AMINO-GUANIDINE CHLORIDE; monoaminoguanidinium chloride; N- AMINOGUANIDINE HYDROCHLORIDE; Pharmakon1600-01506176; pimagedine HCl; Pimagedine hydrochloride;GER-11;Aminoguanidinium chloride
AMINOGUANIDINE BICARBONATE
Aminoguanidine Bicarbonate is a white solid, slightly soluble in water .
Aminoguanidine bicarbonate is an inhibitor of NOS (nitric oxide synthase).


CAS Number: 2582-30-1
EC Number: 219-956-7
MDL number: MFCD00012949
Linear Formula: NH2NHC(=NH)NH2 · H2CO3
Molecular Formula: CH6N4.CH2O3 / C2H8N4O3



SYNONYMS:
aminoguanidinium hydrogen carbonate, Aminoguanidine hicarbonate, 1-aminoguanidine carbonate, Aminoguanidine bicarbonate, GUANYLHYDRAZINE BICARBONATE, Aminoguanidine bicarbonate, Aminoguanidine carbonic acid, 1-AMINOGUANIDINE BICARBONATE, Aminoguanidine hydrogen carbonate, 1-AMINOGUANIDINE HYDROGEN CARBONATE, aminoguanidinium hydrogen carbonate, 1-AMINOGUANIDINIUM HYDROGEN CARBONATE, AMINOGUANIDINE BICARBONATE CRYSTALLINE, 1-AMINOGUANIDINIUM HYDROGEN CARBONATE OE, Aminoguanidine hydrogencarbonate, Guanylhydrazine hydrogencarbonate, Aminoguanidine bicarbonate, 2582-30-1, Aminoguanidine hydrogen carbonate, 2200-97-7, Aminoguanidinium bicarbonate, 2-aminoguanidine;carbonic acid, Aminoguanidine carbonate, Aminoguanidine carbonate (1:1), Aminoguanidium hydrogen carbonate, Aminoguanidinium hydrogen carbonate, N1-Aminoguanidine carbonate (1:1), Aminoguanidine hydrogencarbonate, MFCD00012949, BA 51-090222, NSC7887, N''-aminoguanidine; carbonic acid, amino(diaminomethylidene)azanium;hydrogen carbonate, AMINOGUANIDINE; CARBONIC ACID, 1-Aminoguanidine bicarbonate, AMINOGUANIDINECARBONATE, 2-aminoguanidine,carbonic acid, Hydrazinecarboximidamide carbonate, NSC 7887, EINECS 219-956-7, Amino guanidine bicarbonate, Guanidine, amino-, hydrogen carbonate, Ba 51-090222 (VAN), N(sup 1)-Aminoguanidine carbonate (1:1), AI3-52138, Guanylhydrazine hydrogencarbonate, UNII-X2151435R9, aminoguandine bicarbonate, EC 219-956-7, SCHEMBL40128, CH6N4.H2CO3, 1-aminoguanidine; carbonic acid, DTXSID2062537, Aminoguanidine bicarbonate, 97%, Amino guanidine hydrogen carbonate, 1-aminoguanidine carbonic acid salt, HB0111, AKOS015894487, AKOS015901290, hydrazinecarboximidamide bicarbonate salt, hydrazinecarboximidamide carbonic acid salt, LS-12944, A0307, F87308, Q27293343, [amino(hydrazinyl)methylidene]azanium hydrogen carbonate, F0001-0859, Carbonic acid compound with hydrazinecarboximidamide (1:1), 2-Aminoguanidinium hydrogen carbonate, Aminoguanidine hydrocarbonate, Aminoguanidine hydrogencarbonate, Aminoguanidinium hydrogen carbonate, Guanylhydrazine hydrogen carbonate, aminoguanidine bicarbonate, aminoguanidine hydrogen carbonate, aminoguanidinium bicarbonate, aminoguanidine hydrocarbonate, aminoguanidine carbonate 1:1, aminoguanidium hydrogen carbonate, n1-aminoguanidine carbonate 1:1, aminoguanidine hydrogencarbonate, aminoguanidinebicarbonate, hydrazinecarboximidamide carbonate, Carbonic Acid, compd. with Aminoguanidine, Aminoguanidine Bicarbonate, Aminoguanidine Hydrogen Carbonate, Hydrazinecarboximidamide Carbonate, 1-Aminoguanidine Bicarbonate, Aminoguanidine Bicarbonate, Aminoguanidine Carbonate, Aminoguanidine Hydrogen, Aminoguanidine hydrogencarbonate, Guanylhydrazine hydrogencarbonate, Aminoguanidine hydrogencarbonate, Guanylhydrazine hydrogencarbonate, AMINOGUANIDINE HYDROGEN CARBONATE, hydrazinecarboxiMidaMide carbonate, AMINOGUANADINE BICARBONATE, aminoguanidinium hydrogen carbonate, ABGC, 1-AMinoguanidi, AMINOGUANIDINE HCO3, Aminoguanidine bicar, uanidine bicarbonate, Ceramides 100403-19-8, Aminoguanidine hydrogen carbonate, aminoguanidinium hydrogen carbonate, Aminoguanidine hicarbonate, carbonic acid - carbonohydrazonic diamide (1:1), 1-aminoguanidine carbonate, Aminoguanidine carbonic acid, Amino guanidine bicarbonate,



Aminoguanidine Bicarbonate is a white to off-white crystalline powder.
Aminoguanidine Bicarbonate is almost insoluble in water, alcohol and other acids.
Aminoguanidine Bicarbonate is a chemical compound used as precursor for the preparation of aminoguanidine compounds.


Aminoguanidine Bicarbonate has the chemical formula C2H8N4O3.
Aminoguanidine Bicarbonate, also known as aminoguanidinium hydrogen carbonate, is a chemical compound used as a precursor for the preparation of aminoguanidine compounds .


Aminoguanidine Bicarbonate has the chemical formula C2H8N4O3 .
Aminoguanidine Bicarbonate is a white solid, slightly soluble in water .
Aminoguanidine bicarbonate is an inhibitor of NOS (nitric oxide synthase).


Aminoguanidine Bicarbonate is an inhibitor of NOS (nitric oxide synthase).
Aminoguanidine Bicarbonate, also known as Aminoguanidine hydrogen carbonate, is an organic compound with the molecular formula C2H8N4O3, esteemed for its versatile applications in the specialty chemical industry.


Aminoguanidine Bicarbonate, also referred to as Aminoguanidine hydrogen carbonate, is an organic compound with the molecular formula C2H8N4O3.
Aminoguanidine bicarbonate is a chemical compound with the formula CH6N4·H2CO3.
Aminoguanidine Bicarbonate is a white crystalline powder that is soluble in water.


Aminoguanidine bicarbonate is a strong nucleophile and a powerful reducing agent.
Aminoguanidine Bicarbonate is also a useful reagent for the synthesis of heterocycles.



USES and APPLICATIONS of AMINOGUANIDINE BICARBONATE:
Aminoguanidine Bicarbonate is of practical importance because of its use in dyes, dispersants, explosives and other commercial applications.
Aminoguanidine Bicarbonate is used in the synthesis of antitumor agents and antileukemic activity.
Aminoguanidine Bicarbonate is also used in the synthesis of neuraminidase inhibitors in the inhibition of influenze.


Aminoguanidine Bicarbonate is an inhibitor of NOS (nitric oxide synthase).
Aminoguanidine Bicarbonate is used to study the effect of addition of polyamines to rat embryo cell cultures infected with adenovirus type 5.
Synthesis of heterocycles: Aminoguanidine Bicarbonate serves as a reagent for the synthesis of heterocyclic compounds like 1,2,4-triazoles, which have various biological and industrial applications.


Inhibition of nitric oxide synthase: Aminoguanidine Bicarbonate is used to investigate the role of NO in various physiological and pathological processes by inhibiting NOS activity [, ].
Inhibition of advanced glycation end-product (AGE) formation: Aminoguanidine Bicarbonate is employed to study the role of AGEs in diabetes, aging, and other conditions [, ].


Wound healing: Research suggests that aminoguanidine bicarbonate improves wound healing in diabetic rats by preserving collagen ultrastructure and restoring TGF-β1 expression .
Pulmonary fibrosis: Studies indicate that aminoguanidine exhibits potential therapeutic effects in preventing pulmonary fibrosis by reducing collagen deposition and hydroxyproline content in the lungs .


Anticonvulsant activity: Certain derivatives synthesized from aminoguanidine bicarbonate demonstrate potent anticonvulsant activity, offering potential therapeutic applications in epilepsy .
Energetic materials: Aminoguanidine bicarbonate serves as a precursor for the synthesis of high-nitrogen-content energetic materials, which find applications in propellants, explosives, and pyrotechnics


Aminoguanidine is a pharmaceutical drug that has been used for the treatment of chronic renal failure and congestive heart failure.
Aminoguanidine Bicarbonate has also been studied for its potential use in Alzheimer's disease. Aminoguanidine Bicarbonate is the most commonly used form of aminoguanidine in clinical trials.


Aminoguanidine Bicarbonate can be synthesized by reacting malonic acid with hydrochloric acid and copper metal hydroxide, which produces copper complexes and aminoguanidine bicarbonate.


Aminoguanidine Bicarbonate inhibits the production of inflammatory cytokines, such as tumor necrosis factor-α and interleukins, and activates endothelial nitric oxide synthase, leading to vasodilation and inhibition of platelet aggregation.
Aminoguanidine Bicarbonate is an inhibitor of NOS (nitric oxide synthase).


Biochem/physiol Actions Aminoguanidine bicarbonate protects the cells infected with
Aminoguanidine Bicarbonate can be used as raw materials for the synthesis of pharmaceuticals, pesticides, dyes, foaming agents and explosives.
In the realm of specialty chemicals, Aminoguanidine Bicarbonate proves to be a valuable asset with its wide-ranging capabilities.


While Aminoguanidine Bicarbonate's protective effects against adenovirus-induced chromosomal damage and its role in modulating nitric oxide synthesis are noteworthy, its primary significance lies in its contribution to the specialty chemical sector.
With a focus on the specialty chemical industry, Aminoguanidine Bicarbonate finds utility in producing cutting-edge chemicals catering to diverse sectors.


From high-performance additives to specialized coatings and catalysts, Aminoguanidine Bicarbonate's presence in specialty chemical formulations enhances the performance and functionality of various end product.
The potential of Aminoguanidine Bicarbonate to shield cells from adenovirus-induced chromosomal damage showcases its prowess in cellular defense mechanisms, promising to bolster the immune response against viral infections.


Acting as an inhibitor of NOS, Aminoguanidine Bicarbonate exerts control over the intricate nitric oxide synthesis process, paving the way for therapeutic interventions in conditions where excess nitric oxide could cause detrimental effects.
Aminoguanidine Bicarbonate is used to study the effect of addition of polyamines to rat embryo cell cultures infected with adenovirus type 5.


Significantly, Aminoguanidine Bicarbonate's role in combating diabetic vascular dysfunction highlights its clinical relevance in managing diabetes.
By mitigating vascular impairments associated with diabetes, Aminoguanidine Bicarbonate contributes to the preservation of cardiovascular health, potentially reducing the risk of severe complications stemming from diabetic-related vascular issues.


Beyond its biological effects, Aminoguanidine Bicarbonate emerges as an indispensable resource in the realm of chemical synthesis.
As a foundational building block for diverse pharmaceuticals, Aminoguanidine Bicarbonate empowers researchers and manufacturers to create innovative drugs targeting a wide range of medical conditions.


Additionally, Aminoguanidine Bicarbonate's application in pesticide production fortifies agricultural practices, ensuring enhanced crop protection and improved yields.
Furthermore, Aminoguanidine Bicarbonate's relevance in the production of dyes and foaming agents underscores its significance in the industrial sector.


Its unique properties make Aminoguanidine Bicarbonate an ideal candidate for creating vibrant and durable dyes, catering to various industries such as textiles, cosmetics, and more.
Simultaneously, Aminoguanidine Bicarbonate's capacity as a foaming agent plays a crucial role in the production of numerous consumer products, ranging from personal care items to industrial materials.


Aminoguanidine Bicarbonate has a wide range of applications in the pharmaceutical and specialty chemical industries.
In scientific research, aminoguanidine bicarbonate is primarily used as a reagent for the synthesis of other compounds and as an inhibitor of various enzymes.
Aminoguanidine Bicarbonate was used to study the effect of addition of polyamines to rat embryo cell cultures infected with adenovirus type 5.



MOLECULAR STRUCTURE ANALYSIS OF AMINOGUANIDINE BICARBONATE:
*Condensation reactions:
Aminoguanidine bicarbonate can react with aldehydes and ketones to form imines, with carboxylic acids to form amides, and with esters to form amidines.

*Cyclization reactions:
Aminoguanidine bicarbonate can be used to synthesize heterocycles such as 1,2,4-triazoles.

*Nitration reactions:
Aminoguanidine bicarbonate can be nitrated to form nitroguanidine .



MECHANISM OF ACTION OF AMINOGUANIDINE BICARBONATE:
*Inhibition of nitric oxide synthase (NOS):
Aminoguanidine Bicarbonate acts as an inhibitor of NOS, particularly inducible NOS (iNOS), by competing with L-arginine for the enzyme's active site.
This inhibition reduces NO production and its downstream effects.

Inhibition of advanced glycation end-product (AGE) formation:
Aminoguanidine bicarbonate interferes with the formation of AGEs, which are implicated in diabetic complications and other pathological conditions.
Aminoguanidine Bicarbonate acts as a nucleophile, trapping reactive carbonyl compounds that contribute to AGE formation.


*Antioxidant activity:
Aminoguanidine Bicarbonate demonstrates antioxidant properties by scavenging reactive oxygen species (ROS) and protecting cells from oxidative stress



PHYSICAL AND CHEMICAL PROPERTIES OF AMINOGUANIDINE BICARBONATE:
Aminoguanidine Bicarbonate is a white fine crystalline powder. Soft, practically insoluble in water.
Aminoguanidine Bicarbonate is insoluble in alcohol and other acids. Aminoguanidine Bicarbonate is unstable when heated, and gradually decomposes when it exceeds 50 ° C, turns red when it is heated to 100 ° C.
In an oil bath, and decomposes completely when Aminoguanidine Bicarbonate is heated to 171-173 ° C.



BIOCHEM/PHYSIOL ACTIONS OF AMINOGUANIDINE BICARBONATE:
Aminoguanidine Bicarbonate protects the cells infected with adenovirus from chromosomal damage.
Aminoguanidine is a specific and highly effective inhibitor of diamine oxidase present in fetal calf serum.



SYNTHESIS OF AMINOGUANIDINE BICARBONATE:
A synthesis method of Aminoguanidine Bicarbonate includes reacting an acidic aqueous hydrazine hydrate solution with calcium cyanamide in an elevated temperature to produce an aminoguanidine solution, recovering the solution, and reacting therewith an alkali metal bicarbonate to produce relatively high purity Aminoguanidine Bicarbonate.



PROPERTIES OF AMINOGUANIDINE BICARBONATE:
Chemical:
Addition of an equimolar amount of freebase aminoguanidine to Aminoguanidine Bicarbonate will yield aminoguanidinium carbonate.
Aminoguanidine Bicarbonate will react with acids to yield their respective salts.
X-ray analysis has shown that solid Aminoguanidine Bicarbonate is actually a zwitterionic molecule, 2-guanidinium-1-aminocarboxylate monohydrate.

Physical:
Aminoguanidinium bicarbonate is a white solid, slightly soluble in water.
Recrystallization from hot water is possible, but some decomposition always occurs and reprecipitation tends to be slow and incomplete.



SYNTHESIS ANALYSIS OF AMINOGUANIDINE BICARBONATE:
Aminoguanidine bicarbonate can be synthesized by reacting hydrazine hydrate with cyanamide in the presence of carbon dioxide.
The reaction is typically carried out in water at a temperature of 70-80°C.
Aminoguanidine Bicarbonate is then isolated by filtration and recrystallized from water.

Aminoguanidine Bicarbonate can be prepared by reacting calcium cyanamide with hydrazine sulfate .
Aminoguanidine Bicarbonate can also be easily prepared by reducing nitroguanidine with zinc powder .
Another method involves adding zinc powder to a stirred suspension of nitroguanidine in ammonium sulfate solution .



PHYSICAL AND CHEMICAL PROPERTIES ANALYSIS OF AMINOGUANIDINE BICARBONATE:
Melting point: Decomposes at 150°C .
Solubility: Soluble in water; slightly soluble in ethanol .
pH: 7-8 (in aqueous solution) .

Aminoguanidine Bicarbonate is a white solid, slightly soluble in water .
Aminoguanidine Bicarbonate has a density of 1.56 g/cm3 at 20 °C .
Aminoguanidine Bicarbonate decomposes when boiled .



MOLECULAR STRUCTURE ANALYSIS OF AMINOGUANIDINE BICARBONATE:
The molecular weight of Aminoguanidine bicarbonate is 136.1099 g/mol .
The IUPAC Standard InChI name of Aminoguanidine Bicarbonate is InChI=1S/CH6N4.CH2O3/c2-1(3)5-4;2-1(3)4/h4H2, (H4,2,3,5); (H2,2,3,4) .



CHEMICAL REACTIONS ANALYSIS OF AMINOGUANIDINE BICARBONATE:
Aminoguanidine bicarbonate will react with acids to yield their respective salts .
Addition of an equimolar amount of freebase aminoguanidine to aminoguanidine bicarbonate will yield aminoguanidinium carbonate.



PREPARATION OF AMINOGUANIDINE BICARBONATE:
Aminoguanidine Bicarbonate can be prepared by reacting calcium cyanamide with hydrazine sulfate.
Aminoguanidine Bicarbonate can also be easily prepared by reducing nitroguanidine with zinc powder.
Diachrynic used this route obtaining a great yield:
41.14 g zinc powder (629 mmol, 3.3 molar eq.) are weighed and put to the side.

Into a reaction flask of at least 500 mL are put 20.00 g nitroguanidine (192 mmol, 1 molar eq.) and 47.62 g of ammonium sulfate (360 mmol, 1.88 molar eq.) in 285 mL of water.
The suspension is stirred and not everything dissolves, this is expected.

The reaction flask is immersed in an ice bath and equipped with magnetic stirring and a thermometer.
Stirring is started.
Once the solution reaches 10 °C the addition of small spatulas of zinc powder at a time is started.

Monitor the exotherm and don't add too much at once, however the reaction is fairly easy to control.
3-4 spatulas of zinc can be added at a time, making the temperature jump up by 5-8 °C.
The reaction was kept between 5-15 °C, leaning to the latter temperature.

The complete addition of zinc took about 1 hour, during which the ice bath was refilled just once.
Afterwards the reaction was left stirring at about 15 °C for a further 30 minutes.
The pH rose to about 8-9.

Using a fritted vacuum filter the zinc oxide sludge was removed, it filtered fairly easily.
The yellow colored filtrate is put into a flask with magnetic stirring, and 8.57 g of 25% ammonia solution (126 mmol, 0.66 molar eq.) are added as well as 28.57 g of sodium bicarbonate (340 mmol, 0.94 molar eq.) with stirring, it dissolves after a short while.

The solution is left standing for 12 h during which the Aminoguanidine Bicarbonate slowly precipitates.
Afterwards the product is vacuum filtered off and air dried.
Yield of aminoguanidine bicarbonate: 15.700 g (115 mmol, 60% based on nitroguanidine)



PHYSICAL and CHEMICAL PROPERTIES of AMINOGUANIDINE BICARBONATE:
CAS Number: 2582-30-1
Molecular Weight: 136.11 g/mol
Beilstein: 3569869
EC Number: 219-956-7
MDL number: MFCD00012949
Exact Mass: 136.05964013 g/mol
Monoisotopic Mass: 136.05964013 g/mol
Topological Polar Surface Area: 148 Ų
Heavy Atom Count: 9
Formal Charge: 0
Complexity: 67.9
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0

Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
Physical State: Crystalline powder
Color: Yellow
Odor: Odorless
Melting Point/Freezing Point: Melting point/range: 170 - 172 °C (decomposition)
Initial Boiling Point and Boiling Range: No data available
Flammability (solid, gas): The product is not flammable.
Upper/Lower Flammability or Explosive Limits: No data available
Flash Point: No data available
Autoignition Temperature: No data available
Decomposition Temperature: No data available
pH: 8.9 at 5 g/l at 20 °C

Viscosity:
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water Solubility: 5 g/l at 25 °C - soluble
Partition Coefficient (n-octanol/water): No data available
Vapor Pressure: No data available
Density: 1.56 g/cm³ at 20 °C
Relative Density: No data available
Relative Vapor Density: No data available
Particle Characteristics: No data available

Explosive Properties: No data available
Oxidizing Properties: None
Other Safety Information: No data available
CBNumber: CB4114194
Molecular Formula: C2H8N4O3
Molecular Weight: 136.11
MDL Number: MFCD00012949
MOL File: 2582-30-1.mol
CAS Number: 2582-30-1
Molecular Weight: 136.11 g/mol
Beilstein: 3569869
EC Number: 219-956-7

MDL number: MFCD00012949
Exact Mass: 136.05964013 g/mol
Monoisotopic Mass: 136.05964013 g/mol
Topological Polar Surface Area: 148 Ų
Heavy Atom Count: 9
Formal Charge: 0
Complexity: 67.9
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

Physical State: Crystalline powder
Color: White to off-white
Odor: Odorless
Melting Point/Freezing Point: 170 - 172 °C (decomposition, lit.)
Initial Boiling Point and Boiling Range: Decomposes
Flammability (solid, gas): The product is not flammable.
Upper/Lower Flammability or Explosive Limits: No data available
Flash Point: No data available
Autoignition Temperature: 245 °C
Decomposition Temperature: No data available
pH: 8.9 (5 g/l, H2O, 20 °C)
Viscosity:

Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water Solubility: Partition Coefficient (n-octanol/water): LogP -6.61 at 25 °C
Vapor Pressure: 2.56E-08 mmHg at 25 °C
Density: 1.56 g/cm³ at 20 °C
Relative Density: No data available
Relative Vapor Density: No data available
Particle Characteristics: No data available
Explosive Properties: No data available
Oxidizing Properties: None
Other Safety Information: No data available
CBNumber: CB4114194
Molecular Formula: C2H8N4O3
Molar Mass: 136.11 g/mol

Hill Formula: C₂H₈N₄O₃
Chemical Formula: CH₆N₄ * H₂CO₃
HS Code: 2928 00 90
Storage Temperature: Store below +30°C
Solubility: 2.7 g/L in H2O at 20 °C
pKa: 6.19 at 20 °C
Bulk Density: 700 kg/m³
Chemical Name: Aminoguanidine bicarbonate
IUPAC Name: 2-aminoguanidine; carbonic acid
SMILES: C(=NN)(N)N.C(=O)(O)O
Canonical SMILES: C(=N[NH3+])([NH3+])N.C(=O)([O-])[O-]
Isomeric SMILES: C(=N/[NH3+])([NH3+])/N.C(=O)([O-])[O-]
InChI: InChI=1/CH6N4.CH2O3/c2-1(3)5-4;2-1(3)4/h4H2,(H4,2,3,5);(H2,2,3,4)/p-2

InChIKey: OTXHZHQQWQTQMW-UHFFFAOYSA-N
BRN: 3569869
Refractive Index: Not available
Specific Gravity: Not available
Hazard Class: Not available
DOT Name: Not available
PubChem CID: 164944
Grade: For synthesis
Assay: 95.00 to 100.00%
Food Chemicals Codex Listed: No
Solubility Information: Solubility in water: Assay Percent Range: 98.5%
Formula Weight: 136.11 g/mol
Percent Purity: 98.50%



FIRST AID MEASURES of AMINOGUANIDINE BICARBONATE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of AMINOGUANIDINE BICARBONATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of AMINOGUANIDINE BICARBONATE:
-Extinguishing media:
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of AMINOGUANIDINE BICARBONATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses:
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P2
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of AMINOGUANIDINE BICARBONATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
*Storage class:
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of AMINOGUANIDINE BICARBONATE:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
hygroscopic
no information available

AMINOGUANIDINE BICARBONATE
Aminoguanidine bicarbonate is a pharmaceutical drug that has been used for the treatment of chronic renal failure and congestive heart failure.
Aminoguanidine bicarbonate has also been studied for its potential use in Alzheimer's disease.
Aminoguanidine bicarbonate is the most commonly used form of aminoguanidine in clinical trials.

CAS: 2582-30-1
MF: C2H8N4O3
MW: 136.11
EINECS: 219-956-7

Synonyms
Aminoguanidine bicarbonate ;Aminoguanidine hydrogen carbonate;AMINOGUANIDINE BICARBONATE CRYSTALLINE;1-AMINOGUANIDINIUM HYDROGEN CARBONATE OE;Aminoguanidine bicarbonate, 98.50%;1-AMINOGUANIDINE BICARBONATE;1-AMINOGUANIDINE HYDROGEN CARBONATE;1-AMINOGUANIDINIUM HYDROGEN CARBONATE;GUANYLHYDRAZINE BICARBONATE;Aminoguanidine bicarbonate;2582-30-1;Aminoguanidine hydrogen carbonate;2200-97-7;2-aminoguanidine;carbonic acid;Aminoguanidinium bicarbonate;Aminoguanidine carbonate (1:1);Aminoguanidium hydrogen carbonate;N1-Aminoguanidine carbonate (1:1);Aminoguanidine carbonate;Aminoguanidine hydrogencarbonate;MFCD00012949;BA 51-090222;NSC7887;N''-aminoguanidine; carbonic acid;amino(diaminomethylidene)azanium;hydrogen carbonate;1-Aminoguanidine bicarbonate;Hydrazinecarboximidamide carbonate;NSC 7887;EINECS 219-956-7;Amino guanidine bicarbonate;Guanidine, amino-, hydrogen carbonate;Ba 51-090222 (VAN);N(sup 1)-Aminoguanidine carbonate (1:1);AI3-52138;Guanylhydrazine hydrogencarbonate;UNII-X2151435R9;aminoguandine bicarbonate;EC 219-956-7;SCHEMBL40128;CH6N4.H2CO3;1-aminoguanidine; carbonic acid;DTXSID2062537;Aminoguanidine bicarbonate, 97%;Amino guanidine hydrogen carbonate;OTXHZHQQWQTQMW-UHFFFAOYSA-N;1-aminoguanidine carbonic acid salt;AMINOGUANIDINE; CARBONIC ACID;HB0111;AKOS015894487;AKOS015901290;hydrazinecarboximidamide bicarbonate salt;hydrazinecarboximidamide carbonic acid salt;LS-12944;A0307;F87308;Q27293343;[amino(hydrazinyl)methylidene]azanium hydrogen carbonate;F0001-0859;Carbonic acid compound with hydrazinecarboximidamide (1:1)

Aminoguanidine bicarbonate can be synthesized by reacting malonic acid with hydrochloric acid and copper metal hydroxide, which produces copper complexes and aminoguanidine bicarbonate.
AGBAAminoguanidine bicarbonateinterleukins, and activates endothelial nitric oxide synthase, leading to vasodilation and inhibition of platelet aggregation.
Aminoguanidinium bicarbonate or aminoguanidine bicarbonate is a chemical compound used as precursor for the preparation of aminoguanidine compounds.
Aminoguanidine bicarbonate has the chemical formula C2H8N4O3.

Aminoguanidine bicarbonate is synonymous with aminoguanidine carbonate, etc.
Aminoguanidine bicarbonate is a white and fine crystalline powder.
Aminoguanidine bicarbonate is soft and almost insoluble in water, insoluble in alcohol and other acids.
Aminoguanidine bicarbonate will become unstable when heated, and will gradually decompose when the temperature exceeds 50°C.

Aminoguanidine bicarbonate is also used in synthetic drugs and dyes.
In the pharmaceutical industry, aminoguanidine bicarbonate is mainly used in the synthesis of guanidine furan, pyrazole, ribavirin, and propyl.
And aminoguanidine bicarbonate can also be used as a raw material for synthetic pesticides, dyes, photosensitizers, foaming agents and explosives.

Aminoguanidine bicarbonate (AG) is a chemical compound that has been studied for its potential therapeutic applications in a variety of medical conditions.
Aminoguanidine bicarbonate is a small molecule consisting of an amine group, a guanidine group, and a bicarbonate group.
Aminoguanidine bicarbonate is a white, odorless, crystalline solid that is slightly soluble in water.
Aminoguanidine bicarbonate has been studied for its potential roles in the treatment of various medical conditions, including diabetes, cancer, and cardiovascular disease.

Aminoguanidine bicarbonate Chemical Properties
Melting point: 170-172 °C (dec.)(lit.)
Density: 1,6 g/cm3
Storage temp.: Store below +30°C.
Solubility H2O: soluble2.7g/L at 20°C
Form: Crystalline Powder
Pka: 6.19[at 20 ℃]
Color: White to off-white
PH: 8.9 (5g/l, H2O, 20℃)
Water Solubility: BRN: 3569869
InChIKey: OTXHZHQQWQTQMW-UHFFFAOYSA-N
LogP: -6.61 at 25℃
CAS DataBase Reference: 2582-30-1(CAS DataBase Reference)
EPA Substance Registry System: Aminoguanidine bicarbonate (2582-30-1)

White to off-white crystalline powder.
Aminoguanidine bicarbonate is almost insoluble in water, alcohol and other acids.
Addition of an equimolar amount of freebase aminoguanidine to aminoguanidine bicarbonate will yield aminoguanidinium carbonate.
Aminoguanidine bicarbonate will react with acids to yield their respective salts.
X-ray analysis has shown that solid aminoguanidine bicarbonate is actually a zwitterionic molecule, 2-guanidinium-1-aminocarboxylate monohydrate.
Aminoguanidine bicarbonate is white or slightly reddish crystalline powder.
Aminoguanidine bicarbonate is almost insoluble in water and alcohol.
Aminoguanidine bicarbonate is unstable when heated, and will gradually decompensated over 45°C and turn red.

Physical
Aminoguanidine bicarbonate is a white solid, slightly soluble in water.
Recrystallization from hot water is possible, but some decomposition always occurs and reprecipitation tends to be slow and incomplete.

Uses
Aminoguanidine bicarbonate is of practical importance because of its use in dyes, dispersants, explosives and other commercial applications.
Aminoguanidine bicarbonate is used in the synthesis of antitumor agents and antileukemic activity.
Also used in the synthesis of neuraminidase inhibitors in the inhibition of influenze.
Aminoguanidine bicarbonate is an inhibitor of NOS (nitric oxide synthase).
Aminoguanidine bicarbonate is used to study the effect of addition of polyamines to rat embryo cell cultures infected with adenovirus type 5.
Aminoguanidine bicarbonate is used as synthetic raw materials for medicine, pesticide, dye, photographic agent, foaming agent and explosive.

Aminoguanidine bicarbonate is an industrial intermediate widely used in industrial fields such as organic synthesis, pharmaceuticals, pesticides, and chemicals.
The endogenous groups of aminoguanidine carbonate can undergo various acylation reactions, condensation reactions, condensation cyclization reactions, etc.

1. The product of aminoguanidine bicarbonate is mainly used in the dye industry.
2. Aminoguanidine bicarbonate can prepare 3-amino-5-carboxy-12.4-triazole, cationic red 2BL, synthesis of X-GRL, aminoguanidine bicarbonate is used (synthetic drug terafidi, propyl prop); aminoguanidine bicarbonate is also can be used for pesticides, nitrofurazone, etc.
3. Aminoguanidine bicarbonate is also a synthetic material for color film, plastic foaming agents and primer tequila.
4. Aminoguanidine bicarbonate is used in the synthesis of medicine and dyes.
In the pharmaceutical industry, aminoguanidine bicarbonate is mainly used to synthesize guanidine furan, pyrazole, ribavirin, and propidium.
5. Aminoguanidine bicarbonate can be used as a synthetic raw material for medicines, pesticides, dyes, photosensitizers, foaming agents, and explosives.

Biochem/physiol Actions
Aminoguanidine bicarbonate protects the cells infected with adenovirus from chromosomal damage.
Aminoguanidine bicarbonate is a specific and highly effective inhibitor of diamine oxidase present in fetal calf serum.

Synthesis
A synthesis method of aminoguanidine bicarbonate includes reacting an acidic aqueous hydrazine hydrate solution with calcium cyanamide in an elevated temperature to produce an aminoguanidine solution, recovering the solution, and reacting therewith an alkali metal bicarbonate to produce relatively high purity aminoguanidine bicarbonate.

Preparation
Aminoguanidine bicarbonate can be prepared by reacting calcium cyanamide with hydrazine sulfate.
Aminoguanidine bicarbonate can also be easily prepared by reducing nitroguanidine with zinc powder.
Diachrynic used this route obtaining a great yield:
41.14 g zinc powder (629 mmol, 3.3 molar eq.) are weighed and put to the side.
Into a reaction flask of at least 500 mL are put 20.00 g nitroguanidine (192 mmol, 1 molar eq.) and 47.62 g of ammonium sulfate (360 mmol, 1.88 molar eq.) in 285 mL of water.
The suspension is stirred and not everything dissolves, this is expected.
The reaction flask is immersed in an ice bath and equipped with magnetic stirring and a thermometer.
Stirring is started.

Once the solution reaches 10 °C the addition of small spatulas of zinc powder at a time is started.
Monitor the exotherm and don't add too much at once, however the reaction is fairly easy to control.
3-4 spatulas of zinc can be added at a time, making the temperature jump up by 5-8 °C.
The reaction was kept between 5-15 °C, leaning to the latter temperature.
The complete addition of zinc took about 1 hour, during which the ice bath was refilled just once.
Afterwards the reaction was left stirring at about 15 °C for a further 30 minutes.
The pH rose to about 8-9.
Using a fritted vacuum filter the zinc oxide sludge was removed, it filtered fairly easily.

The yellow colored filtrate is put into a flask with magnetic stirring, and 8.57 g of 25% ammonia solution (126 mmol, 0.66 molar eq.) are added as well as 28.57 g of sodium bicarbonate (340 mmol, 0.94 molar eq.) with stirring, Aminoguanidine bicarbonate dissolves after a short while.
The solution is left standing for 12 h during which the aminoguanidine bicarbonate slowly precipitates.
Afterwards Aminoguanidine bicarbonate is vacuum filtered off and air dried.
Yield of aminoguanidine bicarbonate: 15.700 g (115 mmol, 60% based on nitroguanidine)
AMINOGUANIDINE HYDROGEN CARBONATE
Aminoguanidine hydrogen carbonate showcases its prowess in cellular defense mechanisms, safeguarding cells from adenovirus-induced chromosomal damage and bolstering the immune response against viral infections.
By mitigating vascular impairments associated with diabetes, Aminoguanidine hydrogen carbonate actively contributes to preserving cardiovascular health, potentially reducing the risk of severe complications arising from diabetic-related vascular issues.
Aminoguanidine hydrogen carbonate's versatility as a raw material plays a pivotal role in advancing drug development and therapeutic solutions, making it an indispensable resource in the pursuit of better healthcare.

CAS Number: 2582-30-1
EC Number: 219-956-7
Chemical Formula: CH6N4·H2CO3
Molecular Weight: 136.11

Synonyms: Aminoguanidine bicarbonate, 2582-30-1, Aminoguanidine hydrogen carbonate, 2200-97-7, 2-aminoguanidine;carbonic acid, Aminoguanidinium bicarbonate, Aminoguanidine carbonate (1:1), Aminoguanidium hydrogen carbonate, N1-Aminoguanidine carbonate (1:1), Aminoguanidine carbonate, Aminoguanidine hydrogencarbonate, MFCD00012949, BA 51-090222, NSC7887, N''-aminoguanidine; carbonic acid, amino(diaminomethylidene)azanium;hydrogen carbonate, 1-Aminoguanidine bicarbonate, Hydrazinecarboximidamide carbonate, NSC 7887, EINECS 219-956-7, Amino guanidine bicarbonate, Guanidine, amino-, hydrogen carbonate, Ba 51-090222 (VAN), N(sup 1)-Aminoguanidine carbonate (1:1), AI3-52138, Guanylhydrazine hydrogencarbonate, UNII-X2151435R9, aminoguandine bicarbonate, EC 219-956-7, SCHEMBL40128, CH6N4.H2CO3, 1-aminoguanidine; carbonic acid, DTXSID2062537, Aminoguanidine bicarbonate, 97%, Amino guanidine hydrogen carbonate, OTXHZHQQWQTQMW-UHFFFAOYSA-N, 1-aminoguanidine carbonic acid salt, AMINOGUANIDINE; CARBONIC ACID, HB0111, AKOS015894487, AKOS015901290, hydrazinecarboximidamide bicarbonate salt, hydrazinecarboximidamide carbonic acid salt, LS-12944, A0307, F87308, Q27293343, [amino(hydrazinyl)methylidene]azanium hydrogen carbonate, F0001-0859, Carbonic acid compound with hydrazinecarboximidamide (1:1)

Aminoguanidine hydrogen carbonate is a pharmaceutical drug that has been used for the treatment of chronic renal failure and congestive heart failure.
Aminoguanidine hydrogen carbonate has also been studied for its potential use in Alzheimer's disease.

Aminoguanidine hydrogen carbonate is the most commonly used form of aminoguanidine in clinical trials.
Aminoguanidine hydrogen carbonate can be synthesized by reacting malonic acid with hydrochloric acid and copper metal hydroxide, which produces copper complexes and Aminoguanidine hydrogen carbonate.
Aminoguanidine hydrogen carbonate inhibits the production of inflammatory cytokines, such as tumor necrosis factor-α and interleukins, and activates endothelial nitric oxide synthase, leading to vasodilation and inhibition of platelet aggregation.

Aminoguanidinium bicarbonate or Aminoguanidine hydrogen carbonate is a chemical compound used as precursor for the preparation of aminoguanidine compounds.
Aminoguanidine hydrogen carbonate has the chemical formula C2H8N4O3.

Aminoguanidine hydrogen carbonate, also referred to as Aminoguanidine bicarbonate, is an organic compound with the molecular formula C2H8N4O3.
Aminoguanidine hydrogen carbonate has a wide range of applications in the pharmaceutical and specialty chemical industries.

The potential of Aminoguanidine hydrogen carbonate to shield cells from adenovirus-induced chromosomal damage showcases Aminoguanidine hydrogen carbonate prowess in cellular defense mechanisms, promising to bolster the immune response against viral infections.
Acting as an inhibitor of NOS, Aminoguanidine hydrogen carbonate exerts control over the intricate nitric oxide synthesis process, paving the way for therapeutic interventions in conditions where excess nitric oxide could cause detrimental effects.

Significantly, Aminoguanidine hydrogen carbonate's role in combating diabetic vascular dysfunction highlights Aminoguanidine hydrogen carbonate clinical relevance in managing diabetes.
By mitigating vascular impairments associated with diabetes, Aminoguanidine hydrogen carbonate contributes to the preservation of cardiovascular health, potentially reducing the risk of severe complications stemming from diabetic-related vascular issues.

Beyond Aminoguanidine hydrogen carbonate's biological effects, Aminoguanidine hydrogen carbonate emerges as an indispensable resource in the realm of chemical synthesis.
As a foundational building block for diverse pharmaceuticals, Aminoguanidine hydrogen carbonate empowers researchers and manufacturers to create innovative drugs targeting a wide range of medical conditions.
Additionally, Aminoguanidine hydrogen carbonate's application in pesticide production fortifies agricultural practices, ensuring enhanced crop protection and improved yields.

Furthermore, the compound's relevance in the production of dyes and foaming agents underscores Aminoguanidine hydrogen carbonate's significance in the industrial sector.
Aminoguanidine hydrogen carbonate's unique properties make it an ideal candidate for creating vibrant and durable dyes, catering to various industries such as textiles, cosmetics, and more.
Simultaneously, Aminoguanidine hydrogen carbonate's capacity as a foaming agent plays a crucial role in the production of numerous consumer products, ranging from personal care items to industrial materials.

Aminoguanidine hydrogen carbonate has chemical structure H2NC(=NH)NHNH2·H2CO3.
Aminoguanidine hydrogen carbonate appears as white crystalline powder.

Aminoguanidine hydrogen carbonate is hygroscopic in nature.
Aminoguanidine hydrogen carbonate or Aminoguanidine bicarbonate or Guanylhydrazine hydrogencarbonate is White crystalline powder, negligibly soluble in water, insoluble in alcohol and other acids.

Aminoguanidine hydrogen carbonate can be used as a raw material for the synthesis of medicines, pesticides, dyes, photographic chemicals and foaming agents.
Aminoguanidine hydrogen carbonate Amino guanidine bicarbonate is used as a drug intermediate.

Aminoguanidine hydrogen carbonate, also known as Aminoguanidine bicarbonate, is an organic compound with the molecular formula C2H8N4O3, highly valued for Aminoguanidine hydrogen carbonate's applications in the pharmaceutical industry.

In the pharmaceutical sector, Aminoguanidine hydrogen carbonate's remarkable capabilities shine through.
Aminoguanidine hydrogen carbonate showcases its prowess in cellular defense mechanisms, safeguarding cells from adenovirus-induced chromosomal damage and bolstering the immune response against viral infections.

Additionally, as an effective inhibitor of NOS (nitric oxide synthase), this compound plays a crucial role in controlling the intricate nitric oxide synthesis process.
As a result, Aminoguanidine hydrogen carbonate opens up avenues for therapeutic interventions in conditions where excessive nitric oxide levels could lead to harmful effects.

One of the most significant clinical applications of Aminoguanidine hydrogen carbonate lies in managing diabetes.
By mitigating vascular impairments associated with diabetes, Aminoguanidine hydrogen carbonate actively contributes to preserving cardiovascular health, potentially reducing the risk of severe complications arising from diabetic-related vascular issues.

However, Aminoguanidine hydrogen carbonate's primary role in the pharmaceutical industry is Aminoguanidine hydrogen carbonate's utility as a foundational building block for a diverse range of pharmaceuticals.
This unique characteristic empowers researchers and manufacturers to create innovative drugs that target a wide spectrum of medical conditions.
Aminoguanidine hydrogen carbonate is versatility as a raw material plays a pivotal role in advancing drug development and therapeutic solutions, making Aminoguanidine hydrogen carbonate an indispensable resource in the pursuit of better healthcare.

Applications of Aminoguanidine hydrogen carbonate:
Aminoguanidine hydrogen carbonate was used to study the effect of addition of polyamines to rat embryo cell cultures infected with adenovirus type 5.

Aminoguanidine is used as an intermediate for the synthesis of pharmaceuticals, agrochemicals, dyestuffs and other organic derivatives (photochemicals, explosives).
Aminoguanidine hydrogen carbonate is used in the purification of acrylic acid to remove aldehydes.

Aminoguanidine hydrogen carbonate protects the cells infected with adenovirus from chromosomal damage.
Aminoguanidine is a specific and highly effective inhibitor of diamine oxidase present in fetal calf serum.

Uses of Aminoguanidine hydrogen carbonate:
Aminoguanidine hydrogen carbonate is also used as a selective inhibitor of inducible nitric oxide synthase in biochemistry.
Aminoguanidine hydrogen carbonate (AGB) is of practical importance because of Aminoguanidine hydrogen carbonate is use in dyes, dispersants, explosives and other commercial applications.

Aminoguanidine hydrogen carbonate is used in the synthesis of antitumor agents and antileukemic activity.
Aminoguanidine hydrogen carbonate is also used in the synthesis of neuraminidase inhibitors in the inhibition of influenze.

Industry Uses:
Intermediate
Other

Biochem/physiol Actions of Aminoguanidine hydrogen carbonate:
Aminoguanidine hydrogen carbonate protects the cells infected with adenovirus from chromosomal damage.
Aminoguanidine is a specific and highly effective inhibitor of diamine oxidase present in fetal calf serum.

General Manufacturing Information of Aminoguanidine hydrogen carbonate:

Industry Processing Sectors:
All Other Chemical Product and Preparation Manufacturing

Preparation of Aminoguanidine hydrogen carbonate:
Aminoguanidinium bicarbonate can be prepared by reacting calcium cyanamide with hydrazine sulfate.
Aminoguanidine hydrogen carbonate can also be easily prepared by reducing nitroguanidine with zinc powder.

Diachrynic used this route obtaining a great yield:
41.14 g zinc powder (629 mmol, 3.3 molar eq.) are weighed and put to the side.
Into a reaction flask of at least 500 mL are put 20.00 g nitroguanidine (192 mmol, 1 molar eq.) and 47.62 g of ammonium sulfate (360 mmol, 1.88 molar eq.) in 285 mL of water.

The suspension is stirred and not everything dissolves, this is expected.
The reaction flask is immersed in an ice bath and equipped with magnetic stirring and a thermometer.
Stirring is started.

Once the solution reaches 10 °C the addition of small spatulas of zinc powder at a time is started.
Monitor the exotherm and don't add too much at once, however the reaction is fairly easy to control.

3-4 spatulas of zinc can be added at a time, making the temperature jump up by 5-8 °C.
The reaction was kept between 5-15 °C, leaning to the latter temperature.

The complete addition of zinc took about 1 hour, during which the ice bath was refilled just once.
Afterwards the reaction was left stirring at about 15 °C for a further 30 minutes.

The pH rose to about 8-9.
Using a fritted vacuum filter the zinc oxide sludge was removed, Aminoguanidine hydrogen carbonate filtered fairly easily.

The yellow colored filtrate is put into a flask with magnetic stirring, and 8.57 g of 25% ammonia solution (126 mmol, 0.66 molar eq.) are added as well as 28.57 g of sodium bicarbonate (340 mmol, 0.94 molar eq.) with stirring, Aminoguanidine hydrogen carbonate dissolves after a short while.
The solution is left standing for 12 h during which the Aminoguanidine hydrogen carbonate slowly precipitates.

Afterwards Aminoguanidine hydrogen carbonate is vacuum filtered off and air dried.

Yield of Aminoguanidine hydrogen carbonate: 15.700 g (115 mmol, 60% based on nitroguanidine)

Production of Aminoguanidine hydrogen carbonate:

1-) Two hundred and sixteen grams (2.07 moles) of nitroguanidine1 and 740 g. (11.3 moles) of purified zinc dust are thoroughly ground together in a mortar, and then enough water (about 400 ml.) is added with stirring with the pestle to form a thick paste.
The paste is transferred to a 3-l (enameled can or beaker surrounded by an ice bath)

A solution of 128 g. (2.14 moles) of glacial acetic acid in 130 ml of water is cooled to 5° in another 3-l (Beaker, which is fitted with a strong mechanical stirrer and surrounded by an ice bath)
The paste of nitroguanidine and zinc dust, cooled to 5°, is added slowly with mechanical stirring, the temperature of the reaction mixture being kept between 5° and 15°.
A total of about 1 kg of cracked ice is added to the mixture from time to time as the mixture becomes too warm or too thick to stir.

The addition of the paste takes about 8 hours, and the final volume of the mixture is about 1.5 l.
The mixture is then slowly warmed to 40° on a water bath with continued stirring, and this temperature is maintained for 1–5 minutes, until reduction is complete.

The solution is immediately separated from the insoluble material by filtration on a 20-cm.
Büchner funnel, and the cake is sucked as dry as possible.

The residue is transferred to the 3-l (beaker, triturated well with 1 l) of water, and then separated from the liquid by filtration.
In the same manner, the residue is washed twice more with two 600-ml. portions of water.

The filtrates are combined and placed in a 5-l (round-bottomed flask)
Two hundred grams of ammonium chloride is added, and the solution is mechanically stirred until solution is complete.

The stirring is continued, and 220 g. (2.62 moles) of sodium bicarbonate is added during a period of about 10 minutes.
The Aminoguanidine hydrogen carbonate begins to precipitate after a few minutes, and the solution is then placed in a refrigerator overnight.

The precipitate is collected by filtration on a Büchner funnel.
The cake is removed to a 1-l (beaker and mixed with a 400-ml) portion of a 5% solution of ammonium chloride and filtered.

Aminoguanidine hydrogen carbonate is again washed with two 400-ml portions of distilled water, the wash solution being removed each time by filtration.
Finally the solid is pressed down on the Büchner funnel; the mat is broken up with a spatula and washed while on the funnel with two 400-ml (portions of 95% ethanol and then with one 400-ml) (portion of ether)
After air drying, the Aminoguanidine hydrogen carbonate amounts to 180–182 g.

2-) 1. The zinc is purified by stirring 1.2 kg of commercial zinc dust with 3 l of 2% hydrochloric acid for 1 minute.

The acid is removed by filtration, and the zinc is washed in a 4-l beaker with one 3-l portion of 2% hydrochloric acid, three 3-l portions of distilled water, two 2-l portions of 95% ethanol, and finally with one 2-l portion of absolute ether, the wash solutions being removed each time by filtration.
Then the material is thoroughly dried and any lumps are broken up in a mortar.

2. The solution becomes basic to litmus after one-half to three-fourths of the paste has been added.
Lower yields are obtained if a larger excess of acetic acid is employed.

3. The state of reduction can be determined by placing 3 drops of the reaction mixture in a test tube containing 5 ml of a 10% solution of sodium hydroxide and then adding 5 ml of a freshly prepared saturated solution of ferrous ammonium sulfate.
A red coloration indicates incomplete reduction; when the reduction is complete, only a greenish precipitate is observed.
The mixture should not be heated after this test shows that reduction is complete.

4. The presence of the ammonium chloride prevents the coprecipitation of zinc salts when sodium bicarbonate is added to the solution to precipitate the aminoguanidine as the bicarbonate.
If the solution is not clear at this step, Aminoguanidine hydrogen carbonate should be filtered.

5. The Aminoguanidine hydrogen carbonate is pure enough for most purposes.
Aminoguanidine hydrogen carbonate should not be recrystallized from hot water, since decomposition will occur.

6. W. W. Hartman and Ross Philips have submitted a procedure suitable for the preparation of Aminoguanidine hydrogen carbonate on a larger scale.
The sulfates of methylisothiourea and of hydrazine are allowed to react with the evolution of methyl mercaptan.

In a 30-gal crock are placed 10 l of water and 5760 g (20 moles) of methylisothiourea sulfate In a 22-l flask, 5.2 kg (40 moles) of hydrazine sulfate is stirred with 12 l of water, and 40% sodium hydroxide is added until all the hydrazine sulfate has dissolved and the solution is just neutral to Congo paper.

The exact amount of alkali is noted and a duplicate amount added.
The hydrazine solution is then added to the 30-gal crock with stirring, as fast as possible, without allowing the foam to overflow the crock.

The mixing is done out-of-doors, or in an efficient hood, since large volumes of methyl mercaptan are evolved.
If the reaction is carried out on a smaller scale in 12- or 22-l flasks, using appropriate amounts of material, the methyl mercaptan evolved may be absorbed in cold sodium hydroxide solution and isolated if desired.

The solution is stirred until evolution of mercaptan stops, and then a few liters of water are distilled off under reduced pressure to free the solution entirely from mercaptan.
The residual liquor is chilled in a crock, and a crop of hydrated sodium sulfate is filtered off, washed with ice water, and discarded.

The filtrate is warmed to 20–25°, 25 ml of glacial acetic acid is added, then 4 kg of sodium bicarbonate, and the solution is stirred vigorously for 5 minutes and thereafter occasionally during an hour, or until the precipitate no longer increases.
The precipitate is filtered with suction and washed with ice water and then with methanol, and is dried at a temperature not above 60–70°.

The yield is 3760 g (69% of the theoretical amount).
Hydrazine sulfate may be recovered from the final filtrate, if the filtrate is strongly acidified with sulfuric acid and allowed to cool.

3. Discussion
Numerous references for the preparation of Aminoguanidine hydrogen carbonate and other salts can be found in an excellent review article by Lieber and Smith.
Aminoguanidine hydrogen carbonate has also been prepared by treating a cyanamide solution at 20–50° with hydrazine and carbon dioxide, and by the electrolytic reduction of nitroguanidine.

Typical Properties of Aminoguanidine hydrogen carbonate:

Chemical:
Addition of an equimolar amount of freebase aminoguanidine to Aminoguanidine hydrogen carbonate will yield aminoguanidinium carbonate.
Aminoguanidinium bicarbonate will react with acids to yield their respective salts.
X-ray analysis has shown that solid Aminoguanidine hydrogen carbonate is actually a zwitterionic molecule, 2-guanidinium-1-aminocarboxylate monohydrate.

Physical:
Aminoguanidinium bicarbonate is a white solid, slightly soluble in water.
Recrystallization from hot water is possible, but some decomposition always occurs and reprecipitation tends to be slow and incomplete.

Handling and storage of Aminoguanidine hydrogen carbonate:

Precautions for safe handling:
Avoid breathing dust/fume/gas/mist/vapor/spray.

Hygiene criteria:
Do not take contaminated clothing out of the workplace.
Wash contaminated clothing before reuse.

Conditions for safe storage, including any incompatibilities:

Storage conditions:
Store in original container.
Store in a well-ventilated place.

Stability and reactivity of Aminoguanidine hydrogen carbonate:

Reaction:
No additional information

Chemical stability:
Aminoguanidine hydrogen carbonate is stable under normal conditions.

Possibility of hazardous reactions:
No additional information

Conditions to avoid:
Avoid dust formation.
Do not allow contact with water.

Incompatible materials:
No additional information

Harmful decomposition products:
No additional information

First Aid Measures of Aminoguanidine hydrogen carbonate:

First aid measures in case of inhalation:
Remove the person to fresh air and allow them to breathe comfortably.
Give oxygen or artificial respiration if necessary.
If you feel unwell, seek medical help.

First aid measures in case of skin contact:
Wash thoroughly with plenty of soap and water.

If skin irritation occurs:
Get medical help/intervention.

First aid measures in case of eye contact:
Remove contact lenses, if present and easy to remove.
Rinse constantly.
Rinse carefully with water for a few minutes.

If eye irritation is persistent:
Get medical advice/care.

First aid measures in case of swallowing:
Rinse mouth out with water.
If you feel unwell, seek medical help.

Most important symptoms and effects, both acute and delayed:

Symptoms/effects following inhalation:
Aminoguanidine hydrogen carbonate causes allergic skin reactions.

Initial signs that require medical attention and special treatment:
Treat symptomatically.

Fir Fighting Measures of Aminoguanidine hydrogen carbonate:

Fire extinguishers:

Suitable extinguishing media:
Dry chemical powder, alcohol-resistant foam, carbon dioxide (CO2).

Unsuitable extinguishing media:
Do not use fire extinguishing materials containing water.

Special hazards arising from the substance or mixture:
No additional information

Advice for firefighting crews:

Protection in case of fire:
Do not attempt to take action without suitable protective equipment.

Accidental Release Measures of Aminoguanidine hydrogen carbonate:

Emergency plans:
Avoid contact with skin, eyes and clothing.

For emergency responders:

Protective equipment:
Use personal protective equipment.

Emergency plans:
Stop exposure.

Environmental precautions:
Long-lasting, toxic effect in the aquatic environment.

Methods and materials for containment and cleaning:

Cleaning operations:
Clean up immediately by sweeping or vacuuming.

Identifiers of Aminoguanidine hydrogen carbonate:
CAS No: [2582-30-1]
Product Code: FA33808
MDL No: MFCD00012949
Chemical Formula: CH6N4·H2CO3
Molecular Weight: 136.11 g/mol
Smiles: C(=NN)(N)N.C(=O)(O)O
Melting Point: 171.50 °C

Quality Level: 100
Assay: 97%
mp: 170-172 °C (dec.) (lit.)

solubility:
H2O: soluble 2.7 g/L at 20 °C
H2O: soluble 3.3 g/L at 30 °C

SMILES string: OC(O)=O.NNC(N)=N
InChI: 1S/CH6N4.CH2O3/c2-1(3)5-4;2-1(3)4/h4H2,(H4,2,3,5);(H2,2,3,4)
InChI key: OTXHZHQQWQTQMW-UHFFFAOYSA-N

Product Number: A0307
Purity / Analysis Method: >98.0%(T)
Molecular Formula / Molecular Weight: CH6N4·H2CO3 = 136.11
Physical State (20 deg.C): Solid
CAS RN: 2582-30-1
Reaxys Registry Number: 3569869
PubChem Substance ID: 87561960
SDBS (AIST Spectral DB): 1667
MDL Number: MFCD00012949

Synonym(s): Aminoguanidine hydrogencarbonate, Guanylhydrazine hydrogencarbonate
Linear Formula: NH2NHC(=NH)NH2 · H2CO3
CAS Number: 2582-30-1
Molecular Weight: 136.11
Beilstein: 3569869
EC Number: 219-956-7
MDL number: MFCD00012949
PubChem Substance ID: 24846902
NACRES: NA.22

Properties of Aminoguanidine hydrogen carbonate:
Molecular Weight: 136.11 g/mol
Hydrogen Bond Donor Count: 5
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 0
Exact Mass: 136.05964013 g/mol
Monoisotopic Mass: 136.05964013 g/mol
Topological Polar Surface Area: 148Ų
Heavy Atom Count: 9
Complexity: 67.9
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

Physical State: Solid
Solubility: Soluble in water (3.3 mg/ml at 30° C), and water (2.7 mg/ml at 20° C).
Storage: Store at 4° C
Melting Point: 170-172° C (lit.)(dec.)
Boiling Point: 422.4° C at 760 mmHg
Density: 1.60 g/cm3
Refractive Index: n20D ~1.67 (Predicted)

Specifications of Aminoguanidine hydrogen carbonate:
Appearance: White to Light yellow powder to crystal
Purity(Nonaqueous Titration): min. 98.0 %
Purity( Potassium iodate Method): min. 98.0 %

Melting Point: 125°C
Color: White
Ignition Residue: 0.3% max.
Infrared Spectrum: Authentic
Assay Percent Range: 98.5%
Packaging: Plastic Bottle
Linear Formula: H2NNHC(=NH)NH2·H2CO3
Quantity: 250 g
Beilstein: 03,117
Solubility Information: Solubility in water: <5g/L (20°C)
Formula Weight: 136.11
Percent Purity: 98.50%
Physical Form: Crystalline Powder
Chemical Name or Material: Aminoguanidine hydrogen carbonate
AMINOISOBUTANOL
AMINOISOBUTANOL = AMP-95 = 2-AMINO-2-METHYL-1-PROPANOL


CAS Number: 124-68-5
EC Number: 204-709-8
MDL Number: MFCD00008051
Chemical formula: (CH3)2C(NH2)CH2OH / C4H11NO


Aminoisobutanol is an organic compound with the formula H2NC(CH3)2CH2OH.
Aminoisobutanol is colorless liquid that is classified as an alkanolamine.
Aminoisobutanol is a useful buffer and a precursor to numerous other organic compounds.
Aminoisobutanol can be produced by the hydrogenation of 2-aminoisobutyric acid or its esters.


Aminoisobutanol is soluble in water and about the same density as water.
Aminoisobutanol is a precursor to oxazolines via its reaction with acyl chlorides.
Via sulfation of the alcohol, Aminoisobutanol is also a precursor to 2,2-dimethylaziridine.
Aminoisobutanol appears as a clear light colored liquid.


Aminoisobutanol is insoluble in water and about the same density as water.
Aminoisobutanol's Flash point is172 °F.
Aminoisobutanol hydrochloride is also called AMP, a biological buffer component.
Aminoisobutanol is white crystals or viscous liquid


Aminoisobutanol is insoluble in water.
Aminoisobutanol is a clear, colorless liquid that neutralizes acids to form salts and water.
Aminoisobutanol is an alkanolamine.
Aminoisobutanol or aminomethyl propanol is a colorless, viscous liquid that functions as a pH adjuster.


Key attributes include neutralization, dispersancy, pH buffering, non-yellowing, stability, formulation optimization, alkaline pH development and corrosion control, offering inumerous benefits throughout the life cycle of a latex paint compared to regular pH neutralizers, such as ammonia, MEA, NaOH and also branded amines.
Aminoisobutanol is colorless, mobile liquid with a relatively low viscosity remains liquid at temperatures as low as 4°C to permit easy, convenient handling.
Aminoisobutanol is a multifunctional neutralizer containing 2-amino-2-methyl-1-propanol and 5% added water.



USES and APPLICATIONS of AMINOISOBUTANOL:
Cosmetic Uses of Aminoisobutanol: buffering agents
Aminoisobutanol is used to make other chemicals (surface-active agents, vulcanization accelerators, and pharmaceuticals) and as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, leather dressings, textile specialties, polishes, cleaning compounds, and so-called soluble oils.


Aminoisobutanol is also used in hair sprays, wave sets, hair dyes, Pamabrom (drug), and absorbents for acidic gases.
Aminoisobutanol is used as a pigment dispersant for water-based paints, resin solubilizer, corrosion inhibitor, protecting agent for carbonyl groups and in boiler-water treatment
Aminoisobutanol is used to make other chemicals.


Aminoisobutanol is used for the preparation of buffer solutions.
Aminoisobutanol is a component of the drugs ambuphylline and pamabrom.
Aminoisobutanol is also used in cosmetics.
Aminoisobutanol is used in the synthesis of Fepradinol & G-130.


Aminoisobutanol is also used for Isobucaine, and Radafaxine.
Aminoisobutanol is used for the preparation of buffer solution and in cosmetics.
Aminoisobutanol is also used in ATR-FTIR spectroscopic investigation of the carbon monoxide absorption characteristics of a series of heterocyclic diamines.


Aminoisobutanol is used for the preparation of buffer solutions, suitable for the determination of alkaline phosphatase.
Aminoisobutanol is also used in ATR-FTIR spectroscopic investigation of the carbon monoxide absorption characteristics of a series of heterocyclic diamines.
Aminoisobutanol has been used as an component in enzyme assay for screening the alkaline phosphatase activity in sarcoma osteogenic (SaOS-2) cells.


Aminoisobutanol is used for the preparation of buffer solutions.
Aminoisobutanol is used in the preparation of buffer solutions, suitable for the determination of alkaline phosphatase.
Aminoisobutanol is used to make other chemicals (surface-active agents, vulcanization accelerators, and pharmaceuticals) and as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, leather dressings, textile specialties, polishes, cleaning compounds, and so-called soluble oils.


Aminoisobutanol is also used in hair sprays, wave sets, hair dyes, Pamabrom (drug), and absorbents for acidic gases.
Aminoisobutanol is used as a pigment dispersant for water-based paints, resin solubilizer, corrosion inhibitor, protecting agent for carbonyl groups and in boiler-water treatment.
Aminoisobutanol is used pH adjuster that can also be found in lotions, hair and skin care products.


Aminoisobutanol is used in the formulation of creams and lotions, hair sprays, wave sets, hair dyes and colors, eye and facial products, and other hair and skin care products.
Aminoisobutanol is used in latex emulsion paints, it promotes acceptance of colorants.
Aminoisobutanol is used in water-borne coatings adn other aqueous applications.


Aminoisobutanol is used corrosion in boiler water systems can be controlled successfully as the amine additive to remove CO2.
Aminoisobutanol is also used as an intermediate in drug synthetic schemes.
Aminoisobutanol is used Adhesives and Sealants, Building and Construction, Pigment Slurries, Dispersions and Colorants, Resins and Emulsion Polymerization, and Inks and Overprint Varnish.


Aminoisobutanol is used Pharmaceutical Synthesis, Household and Industrial Cleaning, Water Treatment, Chemical Manufacturing and Synthesis, Oil and Gas, Coatings, Inks, Metal working fluids, Adhesives, Rubber, Water treatment, Personal care and pharmaceutical intermediates and other industries.
Aminoisobutanol is used Latex Emulsion Paints, Waterborne Coatings, Polyethylene and Wax, Boiler Water Systems, Metal Working Fluids, Personal Care applications, and Aqueous Solutions and Formulations.


Aminoisobutanol is a multifunctional additive used across a wide range of Household and Industrial Cleaning applications.
Aminoisobutanol provides high-efficiency pH control, enhances dispersion of pigments, controls corrosion, and provides compatibility and stability to water-based formulations.
Aminoisobutanol has exceptional thermal and UV stability and is highly resistant to yellowing.


Aminoisobutanol is used in many cosmetic formulations as a neutralizing agent with low viscosity, which is half of TEA.
Aminoisobutanol contributes to moisture resistance, curl resistance, easy rinsing, and product stability.
Aminoisobutano is especially recommended for aerosol products.
Aminoisobutanol is a multifunctional additive and synthetic building block.


The versatility, compatibility and preferred environmental profile of Aminoisobutanol are valued across a wide range of applications and markets.
Aminoisobutanol provides high-efficiency pH control, enhances dispersion of pigments and latex, controls corrosion, and provides compatibility and stability to water-based formulations.


Aminoisobutanol is commonly used as a pH neutralizer, dispersant, surfactant and compatibilizer in architectural paints, caulks and sealants as well as artist products.
In addition, AMP is the only US EPA VOC-exempt amine .
Aminoisobutanol is recommended for a wide range of applications, such as Architectural and Industrial Coatings, Emulsion

Polymerization, Inks, Adhesives and Solvent-borne alkyds.
Aminoisobutanol is a multifunctional neutralizer containing 2-amino-2-methyl-1-propanol and 5% added water.
Aminoisobutanol acts as a corrosion inhibitor.
Aminoisobutanol is a colorless liquid with relatively low viscosity.


Aminoisobutanol contributes to pH stability, low odor and anticorrosive properties.
Aminoisobutanol promotes acceptance of colorants.
Aminoisobutanol is a very efficient amine for neutralizing the carboxylic acid moieties in acid-functional resins to make them suitable for use in water-borne coatings and other aqueous applications.


In latex emulsion paints, Aminoisobutanol is a very efficient co-dispersant for pigments.
In addition, Aminoisobutanol contributes pH stability, low odor, and anticorrosive properties; furthermore, it promotes acceptance of colorants.
Aminoisobutanol is an effective emulsifier for polyethylene and wax by either the normal emulsification techniques or those requiring pressure.


Aminoisobutanol is a very efficient amine for neutralizing the carboxylic acid moieties in acid-functional resins to make them suitable for use in water-borne coatings and other aqueous applications.
Such coatings formulations exhibit higher gloss and greater water resistance than do formulations based on other neutralizing amines.
Corrosion in boiler-water systems can be controlled successfully by use of Aminoisobutanol as the amine additive to remove CO2.


Aminoisobutanol is a high performance alkanolamine, proven as a multifunctional additive for metalworking fluids.
Aminoisobutanol is a highly efficient alkalinity enhancer which also provides corrosion inhibition properties.
The use of Aminoisobutanol will often improve the blostability of these fluids, which can result in longer fluid life.
Aminoisobutanol is the least aggressive amine towards the cobalt binder in carbide tooling.



As an added feature, Aminoisobutanol enhances the performance of triazine biocides, while reducing levels of airborne formaldehyde. Aminoisobutanol does not contribute to ammonia release as do other amines.
Aminoisobutanol is an important additive for the personal care industry.
Aminoisobutanol is compatible with virtually all fixative
resins.


Aminoisobutanol's high base strength and low molecular weight allow formulators to use significantly less
Aminoisobutanol is used for resin neutralization.
Aminoisobutanol possesses liquid phase corrosion inhibition properties, especially useful for the protection of aerosol cans containing aqueous based formulations.


Aminoisobutanol can also be used to neutralize Carbomer resins, in emulsification together with stearic acid, and to make amides and other derivatives used as cosmetic ingredients (CTFA/INCI designation: Aminomethyl propanol).
Aminoisobutanol also functions in dilute aqueous solutions containing small amounts of formaldehyde to scavenge that which otherwise might be released to the atmosphere.


-Uses of Aminoisobutanol:
*In the synthesis of surface-active agents, vulcanization accelerators, pharmaceuticals.
*As emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, leather dressings, textile specialties, polishes, cleaning compounds, so-called soluble oils. In hair sprays, wave sets and hair dyes.
*Absorbent for acidic gases.


-Uses and Applications of Aminoisobutanol:
*Architectural Coatings
*Industrial and Automotive Coatings
*Epoxies, Polyurethanes and Other Reactive Chemistries
*Adhesives and Sealants
*Building and Construction
*Pigment Slurries, Dispersions and Colorants
*Resins and Emulsion Polymerization
*Inks and Overprint Varnish
*Pharmaceutical Synthesis
*Household and Industrial Cleaning
*Water Treatment
*Chemical Manufacturing and Synthesis
*Oil and Gas



AMINOISOBUTANOL USE BENEFITS INCLUDE, BUT ARE NOT LIMITED TO, THE FOLLOWING:
■ Efficient Amine for Resin Neutralization
– High base strength
– Relatively low molecular weight
■ Multiple Food Contact Approvals
■ Acts as a Co-Dispersant for Particulate
Systems
■ Corrosion Inhibitor for Steam-Condensate
Lines
■ Key Component of Low Cobalt-Leaching
Metalworking Fluids
■ Acts as a Formaldehyde Scavenger
■ Useful Raw Material for Synthesis
Applications
■ Component of Powerful Anionic Emulsifier
Systems



BIOCHEM/PHYSIOL ACTIONS OF AMINOISOBUTANOL:
Aminoisobutanol is a substituted aliphatic alcohol and is used majorly as a pH balancer in cosmetic formulations.
Aminoisobutanol has phototoxic effect as it can interact and penetrate above the sebum layer.
However, Aminoisobutanol is not carcinogenic.



REACTIVITY PROFILE OF AMINOISOBUTANOL:
Aminoisobutanol is an aminoalcohol.
Amines are chemical bases.
They neutralize acids to form salts plus water.
These acid-base reactions are exothermic.
The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base.
Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.



PHYSICAL and CHEMICAL PROPERTIES of AMINOISOBUTANOL:
Chemical formula: C4H11NO
Molar mass: 89.138 g·mol−1
Average mass: 89.136 Da
Monoisotopic mass: 89.084061 Da
Density: 0.934 g/cm3
Melting point: 30–31 °C (86–88 °F; 303–304 K)
Boiling point: 165.5 °C (329.9 °F; 438.6 K)
Solubility in water: Miscible
Solubility in alcohols: Soluble
Min. Purity Spec: 95% (GC)
Physical Form (at 20°C): Liquid
Melting Point: 24-28°C
Boiling Point: 164-166°C
Flash Point: 67°C
Density: 0.934
Long-Term Storage: Store long-term in a cool, dry place

Appearance Form: solid
Color: colorless
Odor: amine-like
Odor Threshold: No data available
pH: No data available
Melting point/freezing point:
Melting point/range: 24 - 28 °C - lit.
Initial boiling point and boiling range: 165 °C - lit.
Flash point: 82,1 °C
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: 0,45 hPa at 20,0 °C
Vapor density: No data available
Density: 0,934 g/cm3 at 25 °C - lit.


Relative density: No data available
Water solubility: 8,9 g/l at 20,0 °C - completely soluble
Partition coefficient:
n-octanol/water: log Pow: -0,63 at 20 °C
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 102 mPa.s at 30,0 °C
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Physical description: A clear light colored liquid.
Boiling point: 329°F
Molecular weight: 89.14
Freezing point/melting point: 89.6°F


Flash point: 153°F
Specific gravity: 0.935
Molecular Weight: 89.14
XLogP3-AA: -0.8
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 1
Exact Mass: 89.084063974
Monoisotopic Mass: 89.084063974
Topological Polar Surface Area: 46.2 Ų
Heavy Atom Count: 6
Formal Charge: 0
Complexity: 42.8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0


Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Appearance (Clarity): Clear
Appearance (Colour): Colouless to pale yellow
Appearance (Form): Liquid
Assay (GC): min. 95%
pH (0.1M aq. solution): 11.0-12.0
Density (g/ml) @ 20°C: 0.928-0.930
Refractive Index (20°C): 1.446-1.448
Boiling Range: 164-166°C
Melting Point: 25-28°C
Water (KF): max. 5%

Melting point: 24-28 °C (lit.)
Boiling point: 165 °C (lit.)
Density: 0.934 g/mL at 25 °C (lit.)
vapor density: 3 (vs air)
vapor pressure: refractive index: n20/D 1.4455(lit.)
Flash point: 153 °F
storage temp.: Store below +30°C.
solubility: H2O: 0.1 M at 20 °C, clear, colorless
form: Low Melting Solid
Specific Gravity: 0.934
color: Colorless
PH: 11.0-12.0 (25℃, 0.1M in H2O)
pka: 9.7(at 25℃)
PH Range: 9.0 - 10.5


Water Solubility: miscible
λmax
λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01
Merck: 14,449
BRN: 505979
Stability: Stable.
Appearance: pale yellow to amber brown liquid to solid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.93400 @ 25.00 °C.
Melting Point: 24.00 to 28.00 °C. @ 760.00 mm Hg
Boiling Point: 165.00 to 166.00 °C. @ 760.00 mm Hg
PH Number: 9.00 to 10.50
Vapor Pressure: 0.566000 mmHg @ 25.00 °C. (est)
Vapor Density: 3 ( Air = 1 )
Flash Point: 154.00 °F. TCC ( 68.00 °C. )
logP (o/w): -0.611 (est)
Soluble in: water, 1000000 mg/L @ 25 °C (exp)



FIRST AID MEASURES of AMINOISOBUTANOL:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of AMINOISOBUTANOL:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of AMINOISOBUTANOL:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.



EXPOSURE CONTROLS/PERSONAL PROTECTION of AMINOISOBUTANOL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Flame retardant antistatic protective clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of AMINOISOBUTANOL:
-Precautions for safe handling:
*Hygiene measures:
Immediately change contaminated clothing.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions
Tightly closed.
Dry.



STABILITY and REACTIVITY of AMINOISOBUTANOL:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available



SYNONYMS:
2-Amino-2-methylpropan-1-ol
Isobutanol-2-amine
Aminoisobutanol
2-Amino-2-methyl-1-propanol
2-Amino-2-methyl-1-propanol
1-Propanol, 2-amino-2-methyl-
2-amino-2-methylpropan-1-ol
AMP-95
AMP
2-aminodimethylethanol
β -aminoisobutanol
2-amino-2-methylpropan-1-ol
2-amino-2-methyl-1-propanol
isobutanol-2-amine
isobutanolamine
2-amino-2-methyl-1-propanol
isobutanol-2-amine
amp regular
2-aminoisobutanol
aminomethylpropanol
2-amino-2-methylpropanol
2-methyl-2-aminopropanol
2-aminodimethylethanol
hydroxy-tert-butylamine
beta.-Aminoisobutanol
1,1-Dimethyl-2-hydroxyethylamine
1-PROPANOL,2-AMINO,2-METHYL
1-Propanol, 2-amino-2-methyl-
2-Amino-1-hydroxy-2-methylpropane
2-Amino-2,2-dimethylethanol
2-Amino-2-methyl-1-propanol
2-Amino-2-methylpropan-1-ol
2-Aminodimethyl Ethanol
2-Aminodimethylethanol
2-Aminoisobutanol
2-Hydroxymethyl-2-propylamine
2-Methyl-2-aminopropanol
2-Methyl-2-aminopropanol-1
A0333;AB1003856
AC1L1Y6F
AC1Q1NMT
AKOS000119511
AMP
AMP 75
AMP 95
AMP Regular
Aminomethyl propanol
Aminomethylpropanol
Amp-95
BB_SC-6588
Corrguard 75
Hydroxy-tert-butylamine
I05-0097
Isobutanol-2-amine
Isobutanolamine
Jsp001620
KV 5088
Oprea1_147215
beta-Aminoisobutanol
beta-Aminoisobutyl alcohol
A-Aminoisobutyl alcohol
1,1-Dimethyl-2-hydroxyethylamine
1-Propanol, 2-amino-2-methyl-
2-Amino-1-hydroxy-2-methylpropane
2-Amino-2,2-dimethylethanol
2-Amino-2-methylpropan-1-ol
2-Amino-2-methylpropanol
2-Aminodimethylethanol
2-Aminoisobutanol
2-Hydroxymethyl-2-propylamine
2-Methyl-2-aminopropanol
2-Methyl-2-aminopropanol-1
AMP
AMP (thinner)
AMP 75
AMP 95
AMP Regular
Aminomethylpropanol
AMP-95
Corrguard 75
Hydroxy-tert-butylamine
Isobutanol-2-amine
KV 5088
beta-Aminoisobutanol
Isobutanolamine
2-Amino-2-methyl-1-propanol
124-68-5
2-Amino-2-methylpropan-1-ol
Aminomethylpropanol
1-Propanol, 2-amino-2-methyl-
2-Aminoisobutanol
Isobutanol-2-amine
AMP Regular
2-AMINO-2-METHYLPROPANOL
Aminomethyl propanol
2-Methyl-2-aminopropanol
2-Aminodimethylethanol
2-Amino-2-methyl-propan-1-ol
Hydroxy-tert-butylamine
Corrguard 75
2-Amino-2,2-dimethylethanol
AMP (thinner)
Amp-95
Isobutanolamine
1,1-Dimethyl-2-hydroxyethylamine
2-Methyl-2-aminopropanol-1
2-Hydroxymethyl-2-propylamine
AMP 95
2-Amino-1-hydroxy-2-methylpropane
.beta.-Aminoisobutanol
AMP 75
NSC 441
KV 5088
MFCD00008051
NSC-441
LU49E6626Q
DSSTox_CID_7032
DSSTox_RID_78283
DSSTox_GSID_27032
beta-Aminoisobutanol
Caswell No. 037
beta-Aminoisobutyl alcohol
CAS-124-68-5
HSDB 5606
EINECS 204-709-8
EPA Pesticide Chemical Code 005801
BRN 0505979
UNII-LU49E6626Q
2-Methyl-2-amino-1-propanol
AI3-03947
A-Aminoisobutyl alcohol
2,2-Dimethyl-ethanolamine
Amino-2,2-dimethylethanol
2-amino 2-methyl propanol
2-amino-2-methyl propanol
2-Amino-2-methyl-1-propanol (90% or less)
EC 204-709-8
Hydroxymethyl-2-propylamine
2-Amino-2-methyl-propanol
Amino-2-methyl-1-propanol
H2NC(CH3)2CH2OH
NCIOpen2_009031
2-amino-2-methyl-1propanol
2-amino-2-methylpropan-1ol
2amino-2-methyl-1-propanol
Oprea1_147215
2-amino-2-methylpropan-l-ol
2-amino-2-methyl 1-propanol
2-amino-2-methyl-1 propanol
2-methyl-2-aminopropan-1-ol
1-Propanol-2-amino-2-methyl
AMP, Technical Grade, 95%
2-amino-2,2,dimethyl-ethanol
CHEMBL122588
NSC441
2-amino-2 -methyl-1-propanol
2-amino-2- methylpropan-1-ol
2-amino-2-methyl-1 -propanol
AMINOMETHYLPROPANOL [II]
DTXSID8027032
2-Amino-2-methyl-propane-1-ol
2-hydroxy-1,1-dimethylethylamine
1-hydroxy-2-methyl-2-propylamine
3-hydroxy-2-methyl-2-propylamine
1-hydroxy-2-methyl-2-aminopropane
AMINOMETHYL PROPANOL [INCI]
AMY25550
STR01693
ZINC1555527
Tox21_201780
Tox21_303149
2-Amino-2-methylpropanol (~95%)
BBL023024
STL284638
1-PROPANOL,2-AMINO,2-METHYL
AKOS000119511
WLN: ZX1 & 1 & 1Q
CS-W013743
SB83772
2-AMINO-2-METHYLPROPANOL
NCGC00249118-01
NCGC00257048-01
NCGC00259329-01
2-Amino-2-methyl-1-propanol, 93-97%
2-AMINO-2-METHYL-1-PROPANOL
DB-041780
A0333
FT-0611018
FT-0661937
2-AMINO-2-METHYL-1-PROPANOL
P20005
Q32703
2-Amino-2-methyl-1-propanol, BioXtra, >=95%
A805277
Q-200228
2-Amino-2-methyl-1-propanol, Technical Grade, 95%
2-Amino-2-methyl-1-propanol, purum, >=97.0% (GC)
2-Amino-2-methyl-1-propanol, technical, >=90% (GC)
F2190-0372
2-Amino-2-methyl-1-propanol, BioUltra, >=99.0% (GC)
2-Amino-2-methyl-1-propanol, SAJ first grade, >=98.0%
2-Amino-2-methyl-1-propanol, ~5% Water, technical grade, 90%
2-AMINO-2-METHYLPROPAN-1-OL
AMP-95
2-Amino-2-methylpropanol
1,1-Dimethyl-2-hydroxyethylamine
Aminomethylpropanol
2-methyl-2-amino-1-propanol
Karl Fischer
2,2-Diethyl-ethanolamine
Isobutanolamine
2-Aminoisobutanol







AMINOSULFONIC ACID
Aminosulfonic Acid, also known as amidosulfonic acid, amidosulfuric acid, and sulfamidic acid, is a molecular compound with the formula H3NSO3.
Aminosulfonic Acid belongs to the class of inorganic compounds known as other non-metal oxides.
Aminosulfonic Acid is mainly a precursor to sweet-tasting compounds.


CAS Number: 5329-14-6
EC Number: 226-218-8
Linear Formula: NH2SO3H
Chemical formula: H3NSO3


Aminosulfonic Acid, also known as amidosulfonic acid, amidosulfuric acid, and sulfamidic acid, is a molecular compound with the formula H3NSO3.
This colourless, water-soluble compound, Aminosulfonic Acid, finds many applications.
Aminosulfonic Acid melts at 205 °C before decomposing at higher temperatures to water, sulfur trioxide, sulfur dioxide and nitrogen.


Aminosulfonic Acid (H3NSO3) may be considered an intermediate compound between sulfuric acid (H2SO4), and sulfamide (H4N2SO2), effectively replacing a hydroxyl (–OH) group with an amine (–NH2) group at each step.
This pattern can extend no further in either direction without breaking down the sulfonyl (–SO2–) moiety.


Sulfamates are derivatives of Aminosulfonic Acid.
Aminosulfonic Acid is mainly a precursor to sweet-tasting compounds.
Reaction with cyclohexylamine followed by addition of NaOH gives C6H11NHSO3Na, sodium cyclamate.


Sulfamates have been used in the design of many types of therapeutic agents such as antibiotics, nucleoside/nucleotide human immunodeficiency virus (HIV) reverse transcriptase inhibitors, HIV protease inhibitors (PIs), anticancer drugs (steroid sulfatase and carbonic anhydrase inhibitors), antiepileptic drugs, and weight loss drugs.


Related compounds are also sweeteners, such as acesulfame potassium.
Aminosulfonic Acid is preferable to hydrochloric acid in household use, due to its intrinsic safety.
If erroneously mixed with hypochlorite based products such as bleach, Aminosulfonic Acid does not form chlorine gas, whereas the most common acids would; the reaction (neutralisation) with ammonia, produces a salt, as depicted in the section above.


Aminosulfonic Acid also finds applications in the industrial cleaning of dairy and brewhouse equipment.
Although Aminosulfonic Acid is considered less corrosive than hydrochloric acid, corrosion inhibitors are often added to the commercial cleansers of which it is a component.


Aminosulfonic Acid belongs to the class of inorganic compounds known as other non-metal oxides.
These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen belongs to the class of 'other non-metals'.


Aminosulfonic Acid, also known as amidosulfonic acid, amidosulfuric acid, and sulfamidic acid, is a molecular compound with the formula H3NSO3.
This colorless, water-soluble compound, Aminosulfonic Acid, finds many applications.
Aminosulfonic Acid, also known as amidosulfonic acid, amidosulfuric acid, aminosulfonic acid, and sulfamidic acid, is a molecular compound with the formula H3NSO3.


Aminosulfonic Acid melts at 205°C before decomposing to water, sulfur trioxide, sulfur dioxide, and nitrogen at higher temperatures.
Aminosulfonic Acid (H3NSO3) can be thought of as an intermediate between sulfuric acid (H2SO4) and sulfamide (H4N2SO2), effectively replacing a hydroxyl (–OH) group with an amine (–NH2) group at each step.


This pattern cannot extend in either direction without cleaving the sulfonyl (-SO2-) moiety.
Sulfamates are derivatives of sulfamic acid.
Offering attractive possibilities in deliming and pickling in the leather industry.


Aminosulfonic Acid is The deprotonated form (sulfamate) is a common counterion for Nickel(II) in electroplating.
Aminosulfonic Acid is slightly soluble in methanol, and insoluble in ethanol and ether.
Characteristics of double functional groups of amino gen and sulphonic radical may go on a chemical reaction with many matters.


Aminosulfonic Acid's melting point is 205℃.
And the decomposing temperature of Aminosulfonic Acid is 209℃.
Aminosulfonic Acid appears as a white crystalline solid.


The density of Aminosulfonic Acid is 2.1 g / cm3.
The melting point of Aminosulfonic Acid is 205 °C.
Aminosulfonic Acid is used to make dyes and other chemicals.


Aminosulfonic Acid is the simplest of the sulfamic acids consisting of a single sulfur atom covalently bound by single bonds to hydroxy and amino groups and by double bonds to two oxygen atoms.
Aminosulfonic Acid is the simplest of the sulfamic acids, consisting of a single sulfur atom covalently bonded to hydroxy and amino groups by single bonds and to two oxygen atoms by double bonds.


Aminosulfonic Acid, also known as amidosulfonic acid, amidosulfuric acid, aminosulfonic acid, sulphamic acid and sulfamidic acid, is a molecular compound with the formula H3NSO3.
This colourless, water-soluble Aminosulfonic Acid finds many applications.


Aminosulfonic Acid melts at 205 °C before decomposing at higher temperatures to water, sulfur trioxide, sulfur dioxide and nitrogen.
Aminosulfonic Acid (H3NSO3) may be considered an intermediate compound between sulfuric acid (H2SO4), and sulfamide (H4N2SO2), effectively replacing a hydroxyl (–OH) group with an amine (–NH2) group at each step.


This pattern can extend no further in either direction without breaking down the sulfonyl (–SO2–) moiety.
Sulfamates are derivatives of Aminosulfonic Acid.



USES and APPLICATIONS of AMINOSULFONIC ACID:
Cleaning agent: Aminosulfonic acid cleaning agent has a wide range of applications. Aminosulfonic Acid can clean scale and rust in boilers, condensers, heat exchangers, jackets, and chemical pipelines.
The United States Department of Agriculture permits using Aminosulfonic Acid as an acid cleaner in fresh meat, poultry, rabbit, and egg processing facilities.


Textile Industry: Aminosulfonic Acid can eliminate excess nitrate in diazotization reactions in the dye industry and as a fixative in textile dyeing.
Aminosulfonic Acid can be used for descaling home coffee and espresso machines and in denture cleaners.
Aminosulfonic Acid is used in many fields.


Aminosulfonic Acid is used as a standard in acidometry because the solid is non-hygroscopic.
Aminosulfonic Acid is used as a catalyst in a variety of organic chemical reactions.
Aminosulfonic Acid has been shown to remove nitrite from a mixture of nitrites and nitrates.


Aminosulfonic Acid acts as a catalyst for the esterification process.
Aminosulfonic Acid can also form a fireproof layer on textiles, and sulfamic acid can make yarn-cleaning agents and other auxiliaries in the textile industry.


Paper Industry: Aminosulfonic Acid can be used as a bleaching aid. It can reduce or eliminate the catalysis of heavy metal ions in the bleaching liquor, thereby ensuring the quality of the bleaching liquor, reducing the oxidation and degradation of metal ions on fibers, preventing the peeling reaction of fibers, and improving the strength and whiteness of pulp.


Petroleum Industry: Aminosulfonic Acid can be used to remove the plugging and improve the permeability of the reservoir.
Aminosulfonic Acid solution is injected into a carbonate-producing formation to double oil production.
Agriculture: Aminosulfonic Acid and ammonium sulfamate were originally developed as herbicides.


They are said to have an exposure effect when applied directly to plants; when applied to the soil, it has a male-killing effect.
Electroplating solution: Aminosulfonic Acid is commonly used in gold or alloy plating. Italy has replaced the fluorosilicic acid bath with a lead sulfamate bath.
This will reduce pollution.


Aminosulfonic Acid is a compound used in synthesis of sweeteners and therapeutic agents
Aminosulfonic Acid is used as a standard in acidometry because the solid is non-hygroscopic.
Aminosulfonic Acid is used as a catalyst in a variety of organic chemical reactions.


Aminosulfonic Acid has been shown to remove nitrite from a mixture of nitrites and nitrates.
Aminosulfonic Acid acts as a catalyst for the esterification process.
Aminosulfonic Acid is a precursor to mainly sweet-tasting compounds. Reaction with cyclohexylamine followed by addition of NaOH gives C6H11NHSO3Na, sodium cyclamate.


Related compounds are also sweeteners such as acesulfame potassium.
Sulfamates are used in the contents of many drugs such as antibiotics, weight loss drugs, nucleoside / nucleotide human immunodeficiency virus (HIV) reverse transcriptase inhibitors, HIV protease inhibitors (PIs), anticancer drugs (steroid sulfatase and carbonic anhydrase inhibitors), antiepileptic drugs.


Aminosulfonic Acid is used as a catalyst for the esterification process.
Aminosulfonic Acid is used for dye and pigment production.
Urea is used as a coagulator for formaldehyde resins.


Aminosulfonic Acid is the main raw material of ammonium sulfamate, a widely used herbicide and flame retardant material for household products.
Aminosulfonic Acid is used in the pulp and paper industry as a chloride stabilizer.
Aminosulfonic Acid is used for the synthesis of nitrous oxide by reacting with nitric acid.


The deprotonated form (sulfamate) is a common counterion for nickel(II) in electroplating.
Aminosulfonic Acid is used to separate nitrite ions from a mixture of nitrite and nitrate ions (NO3− + NO2−) during the qualitative analysis of nitrate with the Brown Ring test.


Aminosulfonic Acid is used as an acidic cleaning agent, typically for metals and ceramics, sometimes as a component of pure or proprietary blends.
Aminosulfonic Acid is often used to remove rust and limescale to replace the cheaper, more volatile and irritating hydrochloric acid.
Aminosulfonic Acid can be used as a descaler in domestic coffee and espresso machines and denture cleaners.


Aminosulfonic Acid can also be used for industrial cleaning of dairy and brewery equipment.
Aminosulfonic Acid can be used as an amphoteric surfactant, metal parts cleaning agents, cyclamate sweeteners, paper pulp bleachers, fire retarders, chlorine (sterilization) stabilizers, and electroplating additives.


Aminosulfonic Acid can get away with surface oxide.
So Aminosulfonic Acid can clean the boiler and sterilize bacterium in water, bleach fiber, wood, and paper, and remove nitrate in tobacco. Aminosulfonic Acid can also be used as raw material for pesticide intermediate.


Aminosulfonic Acid is frequently used for removing rust and limescale, replacing the more volatile and irritating hydrochloric acid, which is cheaper.
Aminosulfonic Acid is often a component of household descalant, for example, Lime-A-Way Thick Gel contains up to 8% sulfamic acid and has pH 2.0–2.2, or detergents used for removal of limescale.


When compared to most of the common strong mineral acids, Aminosulfonic Acid has desirable water descaling properties, low volatility, and low toxicity.
Aminosulfonic Acid forms water-soluble salts of calcium, nickel, and ferric iron.
Aminosulfonic Acid is used Catalyst for esterification process, Dye and pigment manufacturing, Herbicide, Ingredient in Denture Tablets, and Coagulator for urea-formaldehyde resins.


Ingredient in fire extinguishing media: Aminosulfonic Acid is the main raw material for Ammonium sulfamate which is a widely used herbicide and fire retardant material for household product.
Aminosulfonic Acid is used Pulp and paper industry as a chloride stabilizer


Aminosulfonic Acid is used Synthesis of nitrous oxide by reaction with nitric acid
Aminosulfonic Acid is used In household cleaning chemical products such as Cameo.
Aminosulfonic Acid is used as an acidic cleaning agent, sometimes pure or as a component of proprietary mixtures, typically for metals and ceramics.


Aminosulfonic Acid is frequently used for removing rust and limescale, replacing the more volatile and irritating hydrochloric acid.
Aminosulfonic Acid is often a component of householddescaling agents or detergents used for removal of limescale.
When compared to most of the common strong mineral acids, Aminosulfonic Acid has desirable water descaling properties, low volatility, low toxicity and is a water soluble solid forming soluble calcium and iron-III salts.


Aminosulfonic Acid's also finds applications in the industrial cleaning of dairy and brew-house equipment.
Although Aminosulfonic Acid is considered less corrosive than hydrochloric acid due to its lower pKa, corrosion inhibitors are often added to commercial cleansers of which it is a component.


Aminosulfonic Acid is possible that the amino group could act as a ligand under certain circumstances, as does the chloride ion for Fe-III, when hydrochloric acid is used in rust removal.
Aminosulfonic Acid is used as a cleaning agent of descaling


Aminosulfonic Acid is effective descaling agent, it is used for cleaning kinds of industrial equipment and domestic appliances.
Aminosulfonic Acid can remove rust, limescale, corrosion.
Aminosulfonic Acid is widely used in cleaning of metal, ceramic, and boiler compound, floor Surface, household Equipment, condenser, chemical pipelines etc.


Aminosulfonic Acid is used in paper pulp Industry
Aminosulfonic Acid prevents pulp degradation due to temperature at the chlorination and hydrochloride stage.
Aminosulfonic Acid permits bleaching at higher temperature and lower PH without loss of strength.


Aminosulfonic Acid is used in manufacturing of Dyes,Pigments
Aminosulfonic Acid is more effective, the reaction of sulfamic acid with nitrites is practically instantaneous, and it can remove of excess nitrite following diazotization reactions.


Aminosulfonic Acid is used in the dyeing of leather
Aminosulfonic Acid is used in Chlorine Stabilization
Aminosulfonic Acid can be used for stabilizing chlorine in swimming pools and cooling towers.


Aminosulfonic Acid is preferable to hydrochloric acid in household use, due to its intrinsic safety.
If inadvertently mixed with hypochlorite based products such as bleach, Aminosulfonic Acid does not form chlorine gas, whereas the most common acids would; the reaction (neutralisation) with ammonia, produces a salt, as depicted in the section above.


Aminosulfonic Acid also finds applications in the industrial cleaning of dairy and brewhouse equipment.
Although Aminosulfonic Acid is considered less corrosive than hydrochloric acid, corrosion inhibitors are often added to the commercial cleansers of which it is a component.


Aminosulfonic Acid can be used as a descalant for descaling home coffee and espresso machines and in denture cleaners.
Other uses of Aminosulfonic Acid: Catalyst for esterification process, Dye and pigment manufacturing, Herbicide, Descalant for scale removal, Coagulator for urea-formaldehyde resins, and Ingredient in fire extinguishing media.


Aminosulfonic Acid is the main raw material for ammonium sulfamate which is a widely used herbicide and fire retardant material for household products.
Aminosulfonic Acid is used Pulp and paper industry as a chloride stabilizer.
Aminosulfonic Acid is used Synthesis of nitrous oxide by reaction with nitric acid.


Aminosulfonic Acid is The deprotonated form (sulfamate) is a common counterion for nickel(II) in electroplating.
Aminosulfonic Acid is used to separate nitrite ions from mixture of nitrite and nitrate ions( NO3−+ NO2−) during qualitative analysis of nitrate by Brown Ring test.


Aminosulfonic Acid is used Obtaining deep eutectic solvents with urea.
Aminosulfonic Acid is used Silver polishing.
Aminosulfonic Acid is used in the following products: washing and cleaning products, biocides (eg disinfectants, pest control products), polishes, air care products, non-metallic surface treatment products, fuels and polymers.


Aminosulfonic Acid is used in offshore mining and health services.
Release of Aminosulfonic Acid to the environment may occur from industrial use: in processing aids at industrial sites and substances in closed systems with minimal emissions.


Aminosulfonic Acid is used in machine wash fluids/detergents, automotive care products, paints, coatings or adhesives, fragrances, air fresheners, hydraulic fluids in automotive suspension, lubricants in engine oil, brake fluids, coolants in refrigerators, and oil-based electrical heaters.
Aminosulfonic Acid is a water-soluble, moderately strong acid.


An intermediate between sulfuric acid and sulfamide, Aminosulfonic Acid can be used as a precursor to sweet-tasting compounds, a therapeutic drug component, an acidic cleaning agent, and a catalyst for esterification.
Amidosulfonic Acid is mainly a precursor to sweet-tasting compounds. Aminosulfonic Acid has been used in the design of many types of therapeutic agents such as antibiotics, nucleoside/nucleotide human immunodeficiency virus (HIV) reverse transcriptase inhibitors, HIV protease inhibitors (PIs), anti-cancer drugs (steroid sulfatase and carbonic anhydrase inhibitors), anti-epileptic drugs, and weight loss drugs.


Aminosulfonic Acid is mainly a precursor to sweet-tasting compounds. Reaction with cyclohexylamine followed by addition of NaOH gives C6H11NHSO3Na, sodium cyclamate.
Related compounds are also sweeteners, such as acesulfame potassium.


Sulfamates have been used in the design of many types of therapeutic agents such as antibiotics, nucleoside/nucleotide human immunodeficiency virus (HIV) reverse transcriptase inhibitors, HIV protease inhibitors (PIs), anticancer drugs (steroid sulfatase and carbonic anhydrase inhibitors), anti-epileptic drugs, and weight loss drugs.


-Cleaning agent
Aminosulfonic Acid is used as an acidic cleaning agent and descaling agent sometimes pure or as a component of proprietary mixtures, typically for metals and ceramics.
For cleaning purposes, there are different grades based on application such as GP Grade, SR Grade and TM Grade.


-Specific applications of phosphoric acid include:
*In anti-rust treatment by phosphate conversion coating or passivation
*As an external standard for phosphorus-31 nuclear magnetic resonance.
*In phosphoric acid fuel cells.
*In activated carbon production.
*In compound semiconductor processing, to etch Indium gallium arsenide selectively with respect to indium phosphide.
*In microfabrication to etch silicon nitride selectively with respect to silicon dioxide.
*As a pH adjuster in cosmetics and skin-care products.
*As a sanitizing agent in the dairy, food, and brewing industries.


-Cleaning agent:
Aminosulfonic Acid is used as an acidic cleaning agent, sometimes pure or as a component of proprietary mixtures, typically for metals and ceramics.
Aminosulfonic Acid is frequently used for removing rust and limescale, replacing the more volatile and irritating hydrochloric acid, which is cheaper.
Aminosulfonic Acid is often a component of household descaling agents, for example, Lime-A-Way Thick Gel contains up to 8% sulfamic acid and has pH 2.0–2.2, or detergents used for removal of limescale.
When compared to most of the common strong mineral acids, Aminosulfonic Acid has desirable water descaling properties, low volatility, and low toxicity.
Aminosulfonic Acid forms water-soluble salts of calcium and ferric iron.



AMINOSULFONIC ACID MAY BE USED IN THE FOLLOWING STUDIES:
• As catalyst in the synthesis of aryl-14H-dibenzo[a.j]xanthenes.
• As green catalyst for the preparation of amide from ketoxime.
• As ammonia equivalent in the regioselective synthesis of primary allylic amines, via allylic substitution reactions.
• Synthesis of polysubstituted quinolones.

Sulfamic acid may be used in the following processes:
• As a titrant in the determination of the burette injection volume and chemical calibration factor.
• To neutralize excess nitrous acid in the colorimetric paracetamol assay by modified Glynn and Kendal colorimetric method.
• To prevent endogenous mercury (Hg) loss during the urine Hg measurement by inductively coupled plasma mass spectrometry (ICP-MS) method.
• As an acid catalyst and a hypochlorite scavenger in the chlorite oxidation of dialdehyde cellulose (DAC).
• As a heterogeneous catalyst in the synthesis of polyhydroquinoline derivatives by Hantzsch condensation reaction.
• As catalyst in the degradation of bamboo fiber to 5-hydroxymethylfurfural (HMF).
• As an acid reagent in the determination of silicates in water samples based on centrifugal microfluidics.
• As catalyst in the synthesis of deazaoxaflavin at room temperature.



PROPERTIES OF AMINOSULFONIC ACID:
Aminosulfonic Acid is also known as sulfamic acid.
Aminosulfonic Acid is a white orthorhombic crystal and nonvolatile, nonhygroscopic, and smell-less.
Aminosulfonic Acid has high stability at normal temperatures.
Aminosulfonic Acid can maintain its original quality for several years and is freely soluble in water and liquid ammonia, strongly acidic in water solution.



WHAT DOES AMINOSULFONIC ACID LOOK LIKE?
Aminosulfonic Acid is a white, odorless and crystalline solid



IN WHICH SECTORS IS AMINOSULFONIC ACID USED?
*Pharmaceutical industry
*Sweeteners
*Paint and pigment production
*fire prevention systems
*paper industry
*Nitrate nitrite separator in Brown ring test
*Domestic and industrial cleaner / descaler



ALTERNATIVE PARENTS OF AMINOSULFONIC ACID:
*Sulfuric acid monoamides
*Inorganic oxides



SUBSTITUENTS OF AMINOSULFONIC ACID:
*Other non-metal oxide
*Sulfuric acid monoamide
*Inorganic oxide



HOW IS AMINOSULFONIC ACID PRODUCED?
Aminosulfonic Acid is produced industrially by treating urea with a mixture of sulfur trioxide and sulfuric acid (or oleum).
The conversion is carried out in two stages:
OC(NH2)2 + SO3 → OC(NH2)(NHSO3H)
OC(NH2)(NHSO3H) + H2SO4 → CO2 + 2H3NSO3



PRODUCTION OF AMINOSULFONIC ACID:
Aminosulfonic Acid is produced industrially by treating urea with a mixture of sulfur trioxide and sulfuric acid (or oleum).
The conversion is conducted in two stages, the first being sulfamation:
OC(NH2)2 + SO3 → OC(NH2)(NHSO3H)
OC(NH2)(NHSO3H) + H2SO4 → CO2 + 2 H3NSO3
In this way, approximately 96,000 tonnes were produced in 1995.



STRUCTURE AND REACTIVITY OF AMINOSULFONIC ACID:
The compound is well described by the formula H3NSO3, not the tautomer H2NSO2(OH).
The relevant bond distances are 1.44 Å for the S=O and 1.77 Å for the S–N.
The greater length of the S–N is consistent with a single bond.
Furthermore, a neutron diffraction study located the hydrogen atoms, all three of which are 1.03 Å distant from the nitrogen.
In the solid state, the molecule of Aminosulfonic Acid is well described by a zwitterionic form.



HYDROLYSIS OF AMINOSULFONIC ACID:
The crystalline solid is indefinitely stable under ordinary storage conditions, however, aqueous solutions of Aminosulfonic Acid slowly hydrolyse to ammonium bisulfate, according to the following reaction:
H3NSO3 + H2O → [NH4]+[HSO4]−
Its behaviour resembles that of urea, (H2N)2CO.
Both feature amino groups linked to electron-withdrawing centres that can participate in delocalised bonding.
Both liberate ammonia upon heating in water, with urea releasing CO2 while Aminosulfonic Acid releases sulfuric acid.



ACID-BASE REACTIONS OF AMINOSULFONIC ACID:
Aminosulfonic Acid is a moderately strong acid, Ka = 0.101 (pKa = 0.995).
Because the solid is not hygroscopic, Aminosulfonic Acid is used as a standard in acidimetry (quantitative assays of acid content).
H3NSO3 + NaOH → NaH2NSO3 + H2O
Double deprotonation can be effected in ammonia solution to give the anion HNSO2−3.
H3NSO3 + 2 NH3 → HNSO2−3 + 2 NH+4



REACTION WITH NITRIC AND NITROUS ACIDS, AMINOSULFONIC ACID:
With nitrous acid, Aminosulfonic Acid reacts to give nitrogen:
HNO2 + H3NSO3 → H2SO4 + N2 + H2O
while with concentrated nitric acid, it affords nitrous oxide:
HNO3 + H3NSO3 → H2SO4 + N2O + H2O



REACTION WITH HYPOCHLORITE, AMINOSULFONIC ACID:
The reaction of excess hypochlorite ions with Aminosulfonic Acid or a sulfamate salt gives rise reversibly to both N-chlorosulfamate and N,N-dichlorosulfamate ions.
HClO + H2NSO3H → ClNHSO3H + H2O
HClO + ClNHSO3H ⇌ Cl2NSO3H + H2O
Consequently, Aminosulfonic Acid is used as hypochlorite scavenger in the oxidation of aldehydes with chlorite such as the Pinnick oxidation.



REACTION WITH ALCOHOLS, AMINOSULFONIC ACID:
Upon heating Aminosulfonic Acid will react with alcohols to form the corresponding organosulfates.
Aminosulfonic Acid is more expensive than other reagents for doing this, such as chlorosulfonic acid or oleum, but is also significantly milder and will not sulfonate aromatic rings.

Products are produced as their ammonium salts.
Such reactions can be catalyzed by the presence of urea.
Without the presence of any catalysts, Aminosulfonic Acid will not react with ethanol at temperatures below 100 °C.

ROH + H2NSO3H → ROS(O)2O− + NH+4
An example of this reaction is the production 2-ethylhexyl sulfate, a wetting agent used in the mercerisation of cotton, by combining Aminosulfonic Acid with 2-ethylhexanol.



PHYSICAL and CHEMICAL PROPERTIES of AMINOSULFONIC ACID:
Chemical formula: H3NSO3
Molar mass: 97.10 g/mol
Appearance: white crystals
Density: 2.15 g/cm3
Melting point: 205 °C (401 °F; 478 K) decomposes
Solubility in water: Moderate, with slow hydrolysis
Solubility: Moderately soluble in DMF
Slightly:Vsoluble in MeOH
Insoluble in hydrocarbons
Acidity (pKa): 1.0
Physical state: crystalline
Color: white
Odor: odorless
Melting point/freezing point:
Melting point/range: 215 - 225 °C - dec.
Initial boiling point and boiling range: No data available
Flammability (solid, gas): The product is not flammable.
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: > 400 °C
Relative self-ignition temperature for solids
Decomposition temperature: 209 °C
pH: 1,5 at 10 g/l at 20 °C

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 181,4 g/l at 20 °C
soluble470 g/l at 80 °C
Partition coefficient:
n-octanol/water:
No data available
Vapor pressure: 0,008 hPa at 20 °C
0,025 hPa at 100 °C
Density: 2,151 g/cm3 at 25 °C
Relative density: No data available
Relative vapor
density:
No data available
Particle
characteristics:
No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Dissociation constant: -0,99 at 25 °C


Molecular Weight: 97.10 g/mol
XLogP3-AA: -1.6
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0
Exact Mass: 96.98336413 g/mol
Monoisotopic Mass: 96.98336413 g/mol
Topological Polar Surface Area: 88.8Ų
Heavy Atom Count: 5
Formal Charge: 0
Complexity: 92.6
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Melting point °C: 205
Density g/cm³: 2.13 20 °C
Solubility g/ L: 181.4 20 °C,
Soluble with water (soluble in acetone and methanol)
Vapor pressure Pa: 0.8 20 °C
LogP: 0 20 °C
pKa: -0.997 20 °C
pH: 0.41 1 N solution
CAS: 5329-14-6
Molecular Formula: H3NO3S
Molecular Weight (g/mol): 97.088
MDL Number: MFCD00011603
InChI Key: IIACRCGMVDHOTQ-UHFFFAOYSA-N
PubChem CID: 5987
ChEBI
CHEBI:9330
IUPAC Name: sulfamic acid
SMILES: NS(=O)(=O)O
Chemical Formula: H3NSO3
Molecular weight: 97.10 g/mol
Melting point: 205 °C
Density: 2.15 g/cm3

Chemical Formula: H3NO3S
Average Molecular Weight: 97.094
Monoisotopic Molecular Weight: 96.983363657
IUPAC Name: sulfamic acid
Traditional Name: sulfonic acids
CAS Registry Number: 5329-14-6
SMILES: NS(O)(=O)=O
InChI Identifier:
InChI=1S/H3NO3S/c1-5(2,3)4/h(H3,1,2,3,4)
InChI Key: IIACRCGMVDHOTQ-UHFFFAOYSA-N
Molecular form: H3NO3S
Appearance: White Solid
Mol. Weight: 97.09
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: NA



FIRST AID MEASURES of AMINOSULFONIC ACID:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of AMINOSULFONIC ACID:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of AMINOSULFONIC ACID:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of AMINOSULFONIC ACID:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter B-(P2)
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of AMINOSULFONIC ACID:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
*Storage class:
Storage class (TRGS 510): 8B:
Non-combustible



STABILITY and REACTIVITY of AMINOSULFONIC ACID:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available



SYNONYMS:
SULFAMIC ACID
5329-14-6
Amidosulfonic acid
Sulphamic acid
Aminosulfonic acid
Amidosulfuric acid
Imidosulfonic acid
Sulfamidic acid
Sulfaminic acid
Jumbo
Aminosulfuric acid
Sulphamidic acid
Kyselina sulfaminova
Kyselina amidosulfonova
Caswell No. 809
sulfuramidic acid
NSC 1871
Sulfamidsaeure
HSDB 795
amidohydroxidodioxidosulfur
Amidoschwefelsaeure
EINECS 226-218-8
EPA Pesticide Chemical Code 078101
UNII-9NFU33906Q
CHEBI:9330
DTXSID6034005
AI3-15024
9NFU33906Q
NSC-1871
H2NSO3H
MFCD00011603
UN2967
CHEMBL68253
DTXCID4014005
[S(NH2)O2(OH)]
EC 226-218-8
Sulfamic acid [UN2967]
(S(NH2)O2(OH))
CAS-5329-14-6
SULFAMIC ACID, ACS
SULFAMIC ACID, REAG
sulfoamine
Sulphamic-acid-
amidosulphuric acid
Sulfamic acid (ACN
SCALE CLEEN
ALPROJET W
AMINESULFONIC ACID
WLN: ZSWQ
NH2SO3H
Sulfamic acid (packaging)
Sulfamic acid, ACS grade
H3NO3S
SULFAMIC ACID [MI]
NCIOpen2_000675
SULFAMIC ACID [HSDB]
BDBM26994
H3-N-O3-S
NSC1871
Sulfamic acid, p.a., 99.5%
Sulfamic acid, analytical standard
Sulfamic acid, reagent grade, 98%
Tox21_201905
Tox21_303482
NA2967
STL282725
7773-06-0 (mono-ammonium salt)
AKOS005287325
Sulfamic acid, ACS reagent, 99.3%
UN 2967
NCGC00090927-01
NCGC00090927-02
NCGC00257489-01
NCGC00259454-01
Sulfamic acid [UN2967] [Corrosive]
Sulfamic acid, ReagentPlus(R), >=99%
Sulfamic acid, >=99.5% (alkalimetric)
LS-147664
FT-0688102
Sulfamic acid, 99.999% trace metals basis
Sulfamic acid, SAJ first grade, >=99.0%
Sulfamic acid, JIS special grade, >=99.5%
Q412304
W-105754
Sulfamic acid, analytical standard (for acidimetry), ACS reagent
Amidosulfonic acid
Amidosulfuric acid
Aminosulfonic acid
Sulphamic acid
Aminosulfuric acid
Imidosulfonic acid
Sulfamidic acid
UN 2967
Sulfaminic acid
NSC 1871
sulphamidic acid
Amidosulfuric acid
Sulfamic acid descaler
Sulphamidic acid
Sulfamidic acid
Sulfamic acid.
Sulfamic Acid
Alprojet W
Amidosulfuric Acid
Aminesulfonic Acid
Aminosulfonic Acid
Aminosulfuric Acid
NSC 1871
Sulfamidic Acid
Sulfaminic Acid
Sulphamic Acid
Sulfamic acid
5329-14-6
Imidosulfonic acid
Acide sulfamidique
acido sulfamidico
Alprojet W
AMIDOSULFONIC ACID
AMIDOSULFONSAEURE
Amidosulfuric acid
Amidosulphonic acid
Aminesulfonic acid
Aminosulfonic acid
AMINO-SULFONIC ACID
Aminosulfuric acid
NSC 1871
Scale Cleen
Sulfamic acid
Amidosulfonic acid
Amidosulfuric acid
Sulfamidic acid
Sulfamidsaure
Sulfaminic acid
Sulphamic acid
sulphamidic acid
UN 2967
Caswell No. 809
EINECS 226-218-8
EPA Pesticide Chemical Code 078101
Kyselina amidosulfonova
Kyselina sulfaminova
UNII-9NFU33906Q
Amidoschwefelsaeure
Sulfamidsaeure
[S(NH2)O2(OH)]
sulphamidic acid
1266250-83-2
[S(NH2)O2(OH)]
Amidoschwefelsaeure
Amidosulfuric acid
Aminosulfonic acid
Imidosulfonic acid
Sulfamidic acid
Sulfamidsaeure
Sulfaminic acid
Sulphamic acid
Sulphamidic acid
Amidosulfate
Amidosulphate
Amidosulphuric acid
Aminosulfonate
Aminosulphonate
Aminosulphonic acid
Imidosulfonate
Imidosulphonate
Imidosulphonic acid
Sulfamidate
Sulphamidate
Sulphamidsaeure
Sulfaminate
Sulphaminate
Sulphaminic acid
Sulfamate
Sulfamic acid
Sulphamate
Amidosulfonate
Amidosulphonate
Amidosulphonic acid
Ammate
Ammonium sulfamate
Sulfamic acid, indium (+3) salt
Sulfamic acid, magnesium salt (2:1)
Sulfamic acid, monoammonium salt
Sulfamic acid, monopotassium salt
Sulfamic acid, nickel (+2) salt (2:1)
Sulfamic acid, tin (+2) salt
Sulfamic acid, zinc (2:1) salt
7773-06-0 (mono-Ammonium salt)
Amidohydroxidodioxidosulfur
Aminosulfuric acid
Jumbo
Sulfamic acid, acs
Sulfamic acid, reag
Sulfuramidic acid
Amidosulfonic acid
Amidosulfonic Acid
Steradent Active Plus
Sulfamidic Acid
Sulfaminic Acid
Sulphamic Acid
Alprojet W
Amidosulfuric Acid
Aminesulfonic Acid
Aminosulfonic Acid
Aminosulfuric Acid
NSC 1871


AMINOTRIS(METHYLPHOSPHONIC ACID)
Aminotris(methylphosphonic acid), its solid form is crystalline powder, soluble in water, hygroscopic, has excellent chelation, low threshold inhibition and lattice distortion.
Aminotris(methylphosphonic acid) or aminotris(methylenephosphonic acid) is a phosphonic acid with chemical formula C3H12NO9P3.
Aminotris(methylphosphonic acid) has excellent scale inhibition below 200 ℃, low toxicity, good thermal stability, Amino tris(methylene phosphonic acid) can be dissociated into six positive and negative ions in the water, and can form a stable chelate with a variety of metal ions such as iron, copper, aluminum, zinc, calcium, magnesium, etc.

CAS Number: 6419-19-8
Molecular Formula: C3H12NO9P3
Molecular Weight: 299.05
EINECS Number: 229-146-5

Aminotris(methylphosphonic acid) has chelating properties.
Aminotris(methylphosphonic acid) can be synthesized from the Mannich-type reaction of ammonia, formaldehyde, and phosphorous acid, in a manner similar to the Kabachnik–Fields reaction.
Aminotris(methylphosphonic acid) has a more preferable scale inhibition effect on carbonate .

Aminotris(methylphosphonic acid) has good synergy with the polyphosphate, polycarboxylate, nitrite.
Aminotris(methylphosphonic acid) has better antiscale performance than that of polyphosphate through its excellent chelating ability, low threshold inhibition and lattice distortion process.
Aminotris(methylphosphonic acid) can prevent scale formation in water systems.

Aminotris(methylphosphonic acid) is the phosphonate analog of nitrilotriacetic acid.
Aminotris(methylphosphonic acid) is a common chelating agent used in synthetic chemistry.
Aminotris(methylphosphonic acid) is used for the preparation of hexagonal porous three-dimensional structures encapsulating a template, layered structures with intercalated templates or linear polymers, for the synthesis of metal-organic frameworks in combination with uranyl nitrate or the preparation of anticorrosive protective coatings.

Aminotris(methylphosphonic acid) can also be employed as an anti-fouling agent (scale inhibitor).
Aminotris(methylphosphonic acid) can prevent scale formation in water systems.
Aminotris(methylphosphonic acid) is used as detergents and cleaning agent, water treatment and antiscale agent.

Aminotris(methylphosphonic acid) solution is an antiscalant and can be removed form membrane concentrates by iron-coated waste filtration sand.
Aminotris(methylphosphonic acid) is a cement retarder.
Aminotris(methylphosphonic acid) reacts with the aluminum surface to form a coating which is an effective inhibitor of the reaction of evaporated aluminum thin films on glass or silicon with deionized water.

Aminotris(methylphosphonic acid) is a phosphonic acid compound with the chemical formula N(CH2PO3H2)3.
Aminotris(methylphosphonic acid) is also known by other names such as tris(phosphonomethyl)amine, nitrilotrimethylphosphonic acid, and NTMP .
Aminotris(methylphosphonic acid) is widely used in various industrial applications, particularly in industrial water treatment, as an effective scale inhibitor.

Aminotris(methylphosphonic acid) exhibits chelating properties and is known for its ability to inhibit scale formation in water systems.
Aminotris(methylphosphonic acid) can be synthesized through the Mannich-type reaction of ammonia, formaldehyde, and phosphorous acid, similar to the Kabachnik-Fields reaction .
Aminotris(methylphosphonic acid) is a white solid with a molar mass of approximately 299.048 g/mol.

Aminotris(methylphosphonic acid) has a density of 1.33 g/cm3 at 20°C and decomposes at a melting point of 200°C The compound is soluble in water, with a solubility of 61 g/100 mL.
Aminotris(methylphosphonic acid) is also used in the construction of highly-effective and sustainable corrosion protective composite nanofilms, along with trivalent cerium ions.
Aminotris(methylphosphonic acid) has been studied for its degradation processes and analytical methods to determine phosphonic and amino acid groups.

Aminotris(methylphosphonic acid) is a general purpose, cost-effective scale inhibitor based on amino tri methylene phosphonic acid pentasodium salt.
Aminotris(methylphosphonic acid) provides corrosion inhibition with zinc and phosphates and is a good chelant. In cosmetics, pentasodium aminotrimethylene phosphonate is used as an emulsifier.
Amino tris(methylene phosphonic acid) is a common chelating agent used in synthetic chemistry.

Preparation of hexagonal porous three-dimensional structures encapsulating a template, layered structures with intercalated templates or linear polymers.
Synthesis of metal-organic frameworks in combination with uranyl nitrate.
Preparation of ingredient of anticorrosive protective coatings on the steel surface.

Amino tris(methylene phosphonic acid) can also be employed as a scale inhibitor during squeeze treatments in oilfield operations.
Aminotris(methylphosphonic acid) is an effective scale inhibitor used in various industrial applications such as industrial water treatment and detergents.
Aminotris(methylphosphonic acid) further shows good corrosion inhibition properties in presence of zinc and other phosphates.

Aminotris(methylphosphonic acid) can be also used as chelating agent in the textile industry.
The three main raw materials for Amino tris(methylene phosphonic acid) production are phosphorous acid, ammonium chloride, and formaldehyde.
The first two are added into the reactor and heated and stirred until dissolved completely.

Then, formaldehyde will be dropwise. Phosphorus acid can be from the hydrolysis of PCl3 or the production of other chemicals.
If chlorine content needs to be lower than the normal specs, the steam-heating time will be extended.
Aminotris(methylphosphonic acid), also known as ammonium (nitrilotris(methylene))triphosphonate, belongs to the class of organic compounds known as organic phosphonic acids.

These are organic compounds containing phosphonic acid.
Based on a literature review very few articles have been published on Aminotris(methylphosphonic acid).
Aminotris(methylphosphonic acid) is a phosphoric acid derivative produced by a Mannich reaction using ammonia, formaldehyde and phosphoric acid.

The chemical formula of the compound is N(CH2PO3H2)3.
Due to its excellent chelating properties, it is more effective in inhibiting the formation of precipitates (sedimentation) on membranes than polyphosphates.
Aminotris(methylphosphonic acid) is a phosphonate analogue of nitrilotriacetic acid.

Melting point: ~215 °C (dec.)
Boiling point: 746.2±70.0 °C(Predicted)
Density 1.3 g/mL at 25 °C
vapor pressure: 0Pa at 25℃
storage temp.: Sealed in dry,Room Temperature
solubility: Water (Slightly, Heated)
form: Solid
pka: 0.56±0.10(Predicted)
color: White
PH: 0.46
Water Solubility: 500g/L at 20℃
BRN: 1715724
Stability: Stable. Incompatible with bases, strong oxidizing agents.
InChIKey: YDONNITUKPKTIG-UHFFFAOYSA-N
LogP: -3.5

Amino tris(methylene phosphonic acid)is acidic, pay attention to labor protection, should avoid contact with eye and skin, once contacted, flush with plenty of water.
Amino trimethylene phosphonic acid has excellent chelation.
Aminotris(methylphosphonic acid) İs threshold inhibition is low and chemical stability is high.

Aminotris(methylphosphonic acid) is an excellent antiscalant and chelating agent to most metal ions like Ca, Ba, Mg, Fe and Pb, especially Calcium Carbonate (CaCO3).
In the water system, Aminotris(methylphosphonic acid) is difficult to hydrolyze and can distort the lattice.
In a higher concentrated system, Aminotris(methylphosphonic acid) is also a good corrosion inhibitor.

Aminotris(methylphosphonic acid) is used in industrial circulating cool water system of thermal power plant and oil refinery plant.
Aminotris(methylphosphonic acid) can decrease scale formation and inhibit the corrosion of metal equipment and pipeline.
Aminotris(methylphosphonic acid) acid can be used as a chelating agent in woven and dyeing industries and as a metal surface treatment agent.

Usually, Aminotris(methylphosphonic acid) is compounded with organophosphorus acid/salt, polycarboxylic acid/salt.
Aminotris(methylphosphonic acid) solid as crystal powder can also be supplied for cold areas, particularly in water.
Aminotris(methylphosphonic acid) is a compound that exhibits chelating properties and is widely used as a scale inhibitor in industrial water treatment applications.

Aminotris(methylphosphonic acid) is primarily known for its ability to inhibit scale formation in water systems.
Aminotris(methylphosphonic acid) can effectively prevent the precipitation and deposition of scale-forming minerals, such as calcium carbonate and calcium phosphate, which can lead to the fouling of pipes, equipment, and surfaces.
Aminotris(methylphosphonic acid) acts as a chelating agent, meaning it forms stable complexes with metal ions.

This property allows it to sequester and bind metal ions, such as calcium and magnesium, which are often responsible for scale formation.
By forming soluble complexes with these metal ions, Aminotris(methylphosphonic acid) helps to keep them in solution and prevent their precipitation.
In addition to scale inhibition, Aminotris(methylphosphonic acid) has also been found to exhibit corrosion inhibition properties.

Aminotris(methylphosphonic acid) can help protect metal surfaces from corrosion by forming a protective layer or film on the metal surface, which acts as a barrier against corrosive agents.
Aminotris(methylphosphonic acid) can be synthesized through the Mannich-type reaction of ammonia, formaldehyde, and phosphorous acid.
This reaction leads to the formation of the tris(phosphonomethyl)amine structure.

Aminotris(methylphosphonic acid) finds applications in various industries, including cooling water systems, boilers, oil extraction, and desalination plants.
Aminotris(methylphosphonic acid) is commonly used in industrial settings where water quality and scale control are critical.
Aminotris(methylphosphonic acid) has excellent chelation, low threshold inhibition and lattice distortion ability.

Aminotris(methylphosphonic acid) can prevent scale formation, calcium carbonate in particular, in water system.
Aminotris(methylphosphonic acid) has good chemical stability and is hard to be hydrolyzed in water system.
At high concentration, Aminotris(methylphosphonic acid) has good corrosion inhibition.

Aminotris(methylphosphonic acid) is used in industrial circulating cool water system and oilfield water pipeline in fields of thermal power plant and oil refinery plant.
Aminotris(methylphosphonic acid) can decrease scale formation and inhibit corrosion of metal equipment and pipeline.
Aminotris(methylphosphonic acid) can be used as chelating agent in woven and dyeing industries and as metal surface treatment agent.

The solid state of Aminotris(methylphosphonic acid) is crystal powder, soluble in water, easily deliquescence, suitable for usage in winter and freezing districts.
Because of its high purity, Aminotris(methylphosphonic acid) can be used in woven & dyeing industries and as metal surface treatment agent.
Aminotris(methylphosphonic acid) is usually used together with organophosphoric acid, polycarboxylic acid and salt to built all organic alkaline water treatment agent.

Aminotris(methylphosphonic acid) can be used in many different circulating cool water system.
Aminotris(methylphosphonic acid) or aminotris(methylenephosphonic acid) is a phosphonic acid with chemical formula N(CH2PO3H2)3.
Aminotris(methylphosphonic acid) has chelating properties.

Aminotris(methylphosphonic acid) can be synthesized from the Mannich-type reaction of ammonia, formaldehyde, and phosphorous acid.
Aminotris(methylphosphonic acid) has excellent scale inhibition performance, good stability and excellent effect on calcium carbonate scale.
Aminotris(methylphosphonic acid) can form stable complexes with iron, copper, aluminum, zinc and other metal ions, and has good dispersion performance.

Uses:
Aminotris(methylphosphonic acid) is used for power plants, refineries, petrochemicals, fertilizer plant cooling water, oil field injection water system,particularly suitable for hard high-calcium, low concentration multiple systems, such as power plants and high hardness high salinity, bad water quality conditions of the oil pipeline inhibitors,which may decrease the risk of corrosion and scaling of metal equipment and pipeline.
In the textile printing and dyeing industry, Aminotris(methylphosphonic acid) is used as a metal ion chelating agent, metal surface treatment agent.
Aminotris(methylphosphonic acid) is often used with other organic acid, polylactic acid or salt to form organic water treatment agents for circulating cooling water systems under a variety of different water quality conditions.

Aminotris(methylphosphonic acid) is used in drilling fluids as a viscosity regulator.
Aminotris(methylphosphonic acid) can be encountered as a main component of lubricating fluids or as an additive to lubricating fluids.
Aminotris(methylphosphonic acid) is used for the scale prevention of cooling water system, oil pipeline and boiler; Used as the scale inhibitor for the oil pipeline with high hardness, high salinity and bad water quality; Used as scale inhibitor and corrosion inhibitor for the treatment of cooling water, boiler water, oil field water; Used for circulating cooling water of thermal power plant and an oil refinery.

Aminotris(methylphosphonic acid) solution was used to study the mechanism of inhibition of cement hydration by phosphonic acid.
Aminotris(methylphosphonic acid) is an effective scale inhibitor used in various industrial applications such as industrial water treatment and detergents.
Aminotris(methylphosphonic acid) further shows good corrosion inhibition properties in presence of zinc and other phosphates.

Aminotris(methylphosphonic acid) can be also used as chelating agent in the textile industry.
Aminotris(methylphosphonic acid) is used in the following products: water softeners, fertilisers, coating products, cosmetics and personal care products, air care products, polishes and waxes and washing & cleaning products.
Aminotris(methylphosphonic acid) is used in the following areas: building & construction work and agriculture, forestry and fishing.

Aminotris(methylphosphonic acid) is used for the manufacture of: mineral products (e.g. plasters, cement).
Other release to the environment of Aminotris(methylphosphonic acid) is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).
Aminotris(methylphosphonic acid) is used in the following products: water softeners, pH regulators and water treatment products, washing & cleaning products, water treatment chemicals, polishes and waxes and paper chemicals and dyes.

Release to the environment of Aminotris(methylphosphonic acid) can occur from industrial use: formulation of mixtures and formulation in materials.
Aminotris(methylphosphonic acid) is used in the following products: water softeners, pH regulators and water treatment products, water treatment chemicals and washing & cleaning products.
Aminotris(methylphosphonic acid) is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment, mining and formulation of mixtures and/or re-packaging.

Aminotris(methylphosphonic acid) is used for the manufacture of: pulp, paper and paper products, textile, leather or fur, metals, fabricated metal products, machinery and vehicles, furniture and chemicals.
Aminotris(methylphosphonic acid) is employed in water softening formulations.
As a chelating agent, Aminotris(methylphosphonic acid) can sequester and inhibit the precipitation of hardness ions, such as calcium and magnesium, helping to prevent the formation of scale in water systems.

Aminotris(methylphosphonic acid) is utilized in industrial metal cleaning processes where the control of metal ions and prevention of scale formation are crucial.
Aminotris(methylphosphonic acid) is chelating properties contribute to effective metal cleaning solutions.
In the construction industry, Aminotris(methylphosphonic acid) is sometimes used as a concrete additive.

Aminotris(methylphosphonic acid) can function as a retarder, helping to control the setting time of concrete, and also as a dispersant for cement particles.
Aminotris(methylphosphonic acid) is employed in the oil and gas industry to control scale formation in oil wells and production equipment.
Aminotris(methylphosphonic acid) helps maintain the efficiency of oil extraction processes by preventing scale buildup.

Aminotris(methylphosphonic acid) is used in metal surface treatment processes to inhibit corrosion and improve the adhesion of coatings.
Aminotris(methylphosphonic acid) can be incorporated into formulations for metal pre-treatment before painting or coating.
Aminotris(methylphosphonic acid) is employed in the pulp and paper industry to control scale formation and improve the efficiency of various processes, such as pulping and papermaking.

Release to the environment of Aminotris(methylphosphonic acid) can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid and of substances in closed systems with minimal release.
Other release to the environment of Aminotris(methylphosphonic acid) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).
Release to the environment of Aminotris(methylphosphonic acid) can occur from industrial use: manufacturing of the substance, formulation of mixtures and in processing aids at industrial sites.

Aminotris(methylphosphonic acid) Na4 is used in industrial circulating cool water system and oilfield water pipeline in fields of thermal power plant and oil refinery plant.
Aminotris(methylphosphonic acid) is suitable for usage in winter and freezing districts.
Multifunctional and cost effective performance makes it an excellent replacement to other sequestrants e.g EDTA, DTPA, NTA, Metaclaw, Trilon, Versene, Dissolvine, Dequest, Codex, Sequacel, Acinol etc.

Aminotris(methylphosphonic acid) is a common chelating agent used in synthetic chemistry.
Aminotris(methylphosphonic acid) is used as an anti-corrosive additive in metal surface cleaners, as a surfactant that does not foam (automotive care products, cleaning and furniture care products, laundry and dishwashing products).
Also used as a water softener which binds metal ions in a chelating form.

Preparation of hexagonal porous three-dimensional structures encapsulating a template, layered structures with intercalated templates or linear polymers.
Synthesis of metal-organic frameworks in combination with Aminotris(methylphosphonic acid).
Preparation of ingredient of anticorrosive protective coatings on the steel surface.

Aminotris(methylphosphonic acid) can also be employed as a scale inhibitor during squeeze treatments in oilfield operations.

Aminotris(methylphosphonic acid) is used as scale and corrosion inhibitor, deflocculant, sequestrant, and water stabilizer in cooling and boiler water treatment systems.
Aminotris(methylphosphonic acid) is used mainly as a deflocculant and sequestrant (chelating or complexing agent) in industrial water treatment.
Also Aminotris(methylphosphonic acid) is used in cleaners and in stabilizers (peroxide solutions to bleach cotton, linen, jute, rayon, and paper).

Aminotris(methylphosphonic acid) is usually used together with organophosphorus acid, polycarboxylic acid, and salt to built all organic alkaline water treatment chemicals.
Aminotris(methylphosphonic acid) is broadly applied in recirculated cooling water systems for the power station, oil field, and central air-conditioning, etc.
Aminotris(methylphosphonic acid) is also used in the woven and dyeing industry.

Aminotris(methylphosphonic acid) is used in the following products: water softeners, fertilisers, coating products, air care products, washing & cleaning products, polishes and waxes and cosmetics and personal care products.
Other release to the environment of Aminotris(methylphosphonic acid) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Release to the environment of Amino tris(methylene phosphonic acid) can occur from industrial use: in the production of articles, in processing aids at industrial sites and industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).

Other release to the environment of Aminotris(methylphosphonic acid) is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).
Aminotris(methylphosphonic acid) is usually used together with other organophosphoric acid, polycarboxylic acid and salt to built all organic alkaline water treatment agent.

Aminotris(methylphosphonic acid) can be used in many different circulating cool water system. The recommended dosage is 5-20mg/L. As corr
Aminotris(methylphosphonic acid) is widely used as a corrosion inhibitor and a scale inhibitor in water treatment processes, especially in cooling water systems.
Aminotris(methylphosphonic acid) helps prevent the formation of scales and deposits, which can reduce the efficiency of heat exchange equipment and lead to corrosion.

Aminotris(methylphosphonic acid) acts as a chelating agent, forming stable complexes with metal ions, particularly calcium and magnesium.
This chelating property is beneficial in preventing the precipitation of metal ions and improving the effectiveness of other water treatment chemicals.
Aminotris(methylphosphonic acid) is sometimes used in detergents and cleaning formulations to sequester metal ions, preventing them from interfering with the cleaning process.

Aminotris(methylphosphonic acid) contributes to the stabilization of metal ions in the cleaning solution.
Textile Industry: In the textile industry, Aminotris(methylphosphonic acid) may be employed as a stabilizer for hydrogen peroxide bleach baths, helping to control metal impurities that can affect the bleaching process.
Aminotris(methylphosphonic acid) finds applications in the oil and gas industry as a scale and corrosion inhibitor in water injection systems and other processes where water is in contact with metal surfaces.

Aminotris(methylphosphonic acid) is also used in some personal care products, such as shampoos and cosmetics, as a chelating agent.
Aminotris(methylphosphonic acid) is used for power plants, refineries, petrochemicals, fertilizer plant cooling water, oil field injection water system,particularly suitable for hard high-calcium, low concentration multiple systems, such as power plants and high hardness high salinity, bad water quality conditions of the oil pipeline inhibitors,which may decrease the risk of corrosion and scaling of metal equipment and pipeline.
In the textile printing and dyeing industry, Aminotris(methylphosphonic acid) is used as a metal ion chelating agent, metal surface treatment agent.

Aminotris(methylphosphonic acid) is used as a metal ion binder in heating or refrigeration systems to prevent the formation of lime scale deposits.
At the same time, Aminotris(methylphosphonic acid) phosphonate has a corrosion inhibiting function which prevents melting and rusting of iron and copper (bronze) parts.
Aminotris(methylphosphonic acid) is used as an additive to dye baths to bind metal ions, to allow better penetration of the dye into the fabric, and to keep the colour intact.

Aminotris(methylphosphonic acid) is used in the production of distilled water by reverse osmosis as a lime inhibitor.
Aminotris(methylphosphonic acid) binds calcium and magnesium ions, thus keeping the membrane free of blockages and eliminating the need for additional cleaning or washing.
Aminotris(methylphosphonic acid) is often found in membrane cleaners.

Safety Profile:
Aminotris(methylphosphonic acid) may cause irritation to the skin, eyes, and mucous membranes.
Direct contact with the skin or eyes should be avoided.
In case of contact, Aminotris(methylphosphonic acid)'s important to flush the affected area with plenty of water and seek medical attention if irritation persists.

Aminotris(methylphosphonic acid) can be harmful.
Aminotris(methylphosphonic acid)'s not intended for consumption, and ingestion can lead to gastrointestinal discomfort.
While Aminotris(methylphosphonic acid) is not typically associated with significant inhalation hazards, inhalation of dust or mist should be avoided.

Aminotris(methylphosphonic acid) is biodegradable, but its introduction into the environment should be minimized.
Aminotris(methylphosphonic acid) is important to follow proper disposal practices and adhere to local environmental regulations.
Aminotris(methylphosphonic acid) may react with certain metals, and compatibility should be considered when using it in systems containing metals.

Synonyms:
6419-19-8
(Nitrilotris(methylene))triphosphonic acid
Aminotris(methylphosphonic acid)
Aminotrimethylene phosphonic acid
Tris(phosphonomethyl)amine
Ferrofos 509
Dequest 2000
Nitrilotri(methylphosphonic acid)
Dowell L 37
Aminotri(methylene phosphonic acid)
Nitrilotrimethylphosphonic acid
Nitrilotris(methylenephosphonic acid)
Aminotris(methylphosphonic acid)
Aminotri(methylenephosphonic acid)
[bis(phosphonomethyl)amino]methylphosphonic acid
Aminotris(methylenephosphonic acid)
Aminotri(methylphosphonic acid)
Nitrilotrimethanephosphonic acid
NITRILOTRIS(METHYLENE)TRIPHOSPHONIC ACID
Phosphonic acid, [nitrilotris(methylene)]tris-
Aminotris(methanephosphonic acid)
Nitrilotrimethylenephosphonic acid
Amino, tris(methylene phosphonic acid)
Nitrilotrimethylenetris(phosphonic acid)
NITRILOTRIS(METHYLPHOSPHONIC ACID)
(Nitrilotris(methylene))trisphosphonic acid
AI3-51572
Nitrilotris(methylene)trisphosphonic acid
Nitrilotri(methylphosphonic acid) (Aminotris(methylphosphonic acid))
[Nitrilotris(methylene)]trisphosphonic acid
1Y702GD0FG
DTXSID2027624
Sodium (nitrilotris(methylene))triphosphonate
Phosphonic acid, (nitrilotris(methylene))tri-
Aminotri(methylene phosphonic acid), sodium salt
Sodium (nitrilotris(methylene))tris(phosphonate)
{[bis(phosphonomethyl)amino]methyl}phosphonic acid
Nitrilotris(methylene phosphonic acid), sodium salt
(Nitrilotris(methylene))trisphosphonic acid, sodium salt
Phosphonic acid, (nitrilotris(methylene))tri-, sodium salt
(nitrilotris(methylene))tris(phosphonic acid)
[nitrilotris(methylene)]tris(phosphonic acid)
Phosphonic acid, (nitrilotris(methylene))tris-
103333-74-0
dodecylamine-N,N-bis(methylenephosphonic acid) sodium salt
Phosphonic acid, P,P',P''-(nitrilotris(methylene))tris-
Amino tris(methylene phosphonic acid)
(nitrilotris(methylene))tris-Phosphonic acid
[nitrilotris(methylene)]tris-Phosphonic acid
EINECS 229-146-5
BRN 1715724
UNII-1Y702GD0FG
C3H12NO9P3
EINECS 243-900-0
Dequest 2001
EC 229-146-5
EC 243-900-0
Phosphoric acid, (nitrilotris-(methylene))tris-
SCHEMBL21434
4-01-00-03070 (Beilstein Handbook Reference)
CHEMBL260191
DTXCID107624
Amino trimethylene Phoshonic Acid
CHEBI:168957
YDONNITUKPKTIG-UHFFFAOYSA-N
Sym-Trimethylaminetriphosphonic acid
Sodiumamino-tris(methylenesulphonate)
Tox21_202753
MFCD00002138
nitrilotris (methylenephosphonic acid)
AKOS003599784
7611-50-9 (tri-hydrochloride salt)
NCGC00164342-01
NCGC00260300-01
2235-43-0 (penta-hydrochloride salt)
NitrilotrimethylentriphosphonsA currencyure
CAS-6419-19-8
(nitrilotris(methylene))tri-Phosphonic acid
FT-0622276
N0474
(nitrilotris-(methylene))tris-Phosphoric acid
NITRILOTRIS(METHYLENE)TRIPHOSPHONICACID
AMINOTRIMETHYLENE PHOSPHONIC ACID [INCI]
Nitrilotri(methylphosphonic acid), >=97.0% (T)
Q4222241
W-104858
p,p',p''-(Nitrilotris(methylene))tris-Phosphonic acid
.ALPHA.,.ALPHA.',.ALPHA.''-AMINOTRIS(METHYLPHOSPHONIC ACID)
(Nitrilotris(methylene))triphosphonic acid (ca. 50% in Water, ca. 2.2mol/L)
Phosphonic acid, P,P',P''-(nitrilotris(methylene))tris-, sodium salt (1:?)
Amino Phenol
Stearic acid, aluminum salt; Aluminum tristearate; Monoaluminum stearate; Octadecanoic acid, aluminum salt; Hydroxyaluminiumstearat; Aluminiumstearat; Estearato de hidroxialuminio; Estearato de aluminio; Estearato de hidroxialuminio; Stéarate d'aluminium CAS NO:637-12-7, 65324-35-8 (Tristearate) 300-92-5, 36816-06-5 (Distearate)
Aminopropylmethyldiethoxysilane
Reach AZP 902; Reach AZP 908 Superfine GL; Reach AZP 908SUF; Reheis 36 GPC; Reheis AZG; Rezal 36 GP SUF; Rezal 36G; Rezal 36GC; Aluminum zirconium tetrachlorohydrex gly; Aluminum zirconium tetrachlorohydrex glycine complex; UNII-8O386558JE; Westchlor ZR 41; Wickenol CPS 370; Z 535; Z 756; Zirconal 50 CAS NO:134910-86-4
Amino-tris-methylene phosphonic acid (ATMP)
Aluminum chlorhydrol; Aluminum chlorohydrate; Aluminum hydroxide chloride; Aluminum hydroxychloride; Aluminum hydroxychloride dihydrate CAS NO:1327-41-9
AMMONIA %25
Ammonia is a compound of nitrogen and hydrogen with the formula NH3. A stable binary hydride, and the simplest pnictogen hydride, ammonia is a colourless gas with a characteristic pungent smell. It is a common nitrogenous waste, particularly among aquatic organisms, and it contributes significantly to the nutritional needs of terrestrial organisms by serving as a precursor to food and fertilizers. Ammonia, either directly or indirectly, is also a building block for the synthesis of many pharmaceutical products and is used in many commercial cleaning products. It is mainly collected by downward displacement of both air and water.Although common in nature—both terrestrially and in the outer planets of the Solar System—and in wide use, ammonia is both caustic and hazardous in its concentrated form. It is classified as an extremely hazardous substance in the United States, and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities.The global industrial production of ammonia in 2018 was 175 million tonnes,with no significant change relative to the 2013 global industrial production of 175 million tonnes.Industrial ammonia is sold either as ammonia liquor (usually 28% ammonia in water) or as pressurized or refrigerated anhydrous liquid ammonia transported in tank cars or cylinders.NH3 boils at −33.34 °C (−28.012 °F) at a pressure of one atmosphere, so the liquid must be stored under pressure or at low temperature. Household ammonia or ammonium hydroxide is a solution of NH3 in water. The concentration of such solutions is measured in units of the Baumé scale (density), with 26 degrees Baumé (about 30% (by weight) ammonia at 15.5 °C or 59.9 °F) being the typical high-concentration commercial product.Pliny, in Book XXXI of his Natural History, refers to a salt produced in the Roman province of Cyrenaica named hammoniacum, so called because of its proximity to the nearby Temple of Jupiter Amun (Greek Ἄμμων Ammon).However, the description Pliny gives of the salt does not conform to the properties of ammonium chloride. According to Herbert Hoover's commentary in his English translation of Georgius Agricola's De re metallica, it is likely to have been common sea salt.In any case, that salt ultimately gave ammonia and ammonium compounds their name.Ammonia is a chemical found in trace quantities in nature, being produced from nitrogenous animal and vegetable matter. Ammonia and ammonium salts are also found in small quantities in rainwater, whereas ammonium chloride (sal ammoniac), and ammonium sulfate are found in volcanic districts; crystals of ammonium bicarbonate have been found in Patagonia guano.The kidneys secrete ammonia to neutralize excess acid.Ammonium salts are found distributed through fertile soil and in seawater.Ammonia is also found throughout the Solar System on Mars, Jupiter, Saturn, Uranus, Neptune, and Pluto, among other places: on smaller, icy bodies such as Pluto, ammonia can act as a geologically important antifreeze, as a mixture of water and ammonia can have a melting point as low as 173 K (−100 °C; −148 °F) if the ammonia concentration is high enough and thus allow such bodies to retain internal oceans and active geology at a far lower temperature than would be possible with water alone.Substances containing ammonia, or those that are similar to it, are called ammoniacal.Ammonia is a colourless gas with a characteristically pungent smell. It is lighter than air, its density being 0.589 times that of air. It is easily liquefied due to the strong hydrogen bonding between molecules; the liquid boils at −33.3 °C (−27.94 °F), and freezes to white crystals at −77.7 °C (−107.86 °F).Ammonia may be conveniently deodorized by reacting it with either sodium bicarbonate or acetic acid. Both of these reactions form an odourless ammonium salt.The crystal symmetry is cubic, Pearson symbol cP16, space group P213 No.198, lattice constant 0.5125 nm.Liquid ammonia possesses strong ionising powers reflecting its high ε of 22. Liquid ammonia has a very high standard enthalpy change of vaporization (23.35 kJ/mol, cf. water 40.65 kJ/mol, methane 8.19 kJ/mol, phosphine 14.6 kJ/mol) and can therefore be used in laboratories in uninsulated vessels without additional refrigeration. See liquid ammonia as a solvent.Ammonia readily dissolves in water. In an aqueous solution, it can be expelled by boiling. The aqueous solution of ammonia is basic. The maximum concentration of ammonia in water (a saturated solution) has a density of 0.880 g/cm3 and is often known as '.880 ammonia'.Ammonia does not burn readily or sustain combustion, except under narrow fuel-to-air mixtures of 15–25% air. When mixed with oxygen, it burns with a pale yellowish-green flame. Ignition occurs when chlorine is passed into ammonia, forming nitrogen and hydrogen chloride; if chlorine is present in excess, then the highly explosive nitrogen trichloride (NCl3) is also formed.At high temperature and in the presence of a suitable catalyst, ammonia is decomposed into its constituent elements. Decomposition of ammonia is slightly endothermic process requiring 5.5 kcal/mol of ammonia, and yields hydrogen and nitrogen gas. Ammonia can also be used as a source of hydrogen for acid fuel cells if the unreacted ammonia can be removed. Ruthenium and Platinum catalysts were found to be the most active, whereas supported Ni catalysts were the less active.The ammonia molecule has a trigonal pyramidal shape as predicted by the valence shell electron pair repulsion theory (VSEPR theory) with an experimentally determined bond angle of 106.7°.The central nitrogen atom has five outer electrons with an additional electron from each hydrogen atom. This gives a total of eight electrons, or four electron pairs that are arranged tetrahedrally. Three of these electron pairs are used as bond pairs, which leaves one lone pair of electrons. The lone pair repels more strongly than bond pairs, therefore the bond angle is not 109.5°, as expected for a regular tetrahedral arrangement, but 106.7°.This shape gives the molecule a dipole moment and makes it polar. The molecule's polarity, and especially, its ability to form hydrogen bonds, makes ammonia highly miscible with water. The lone pair makes ammonia a base, a proton acceptor. Ammonia is moderately basic; a 1.0 M aqueous solution has a pH of 11.6, and if a strong acid is added to such a solution until the solution is neutral (pH = 7), 99.4% of the ammonia molecules are protonated. Temperature and salinity also affect the proportion of NH4+. The latter has the shape of a regular tetrahedron and is isoelectronic with methane.The ammonia molecule readily undergoes nitrogen inversion at room temperature; a useful analogy is an umbrella turning itself inside out in a strong wind. The energy barrier to this inversion is 24.7 kJ/mol, and the resonance frequency is 23.79 GHz, corresponding to microwave radiation of a wavelength of 1.260 cm. The absorption at this frequency was the first microwave spectrum to be observed.One of the most characteristic properties of ammonia is its basicity. Ammonia is considered to be a weak base. It combines with acids to form salts; thus with hydrochloric acid it forms ammonium chloride (sal ammoniac); with nitric acid, ammonium nitrate, etc. Perfectly dry ammonia will not combine with perfectly dry hydrogen chloride; moisture is necessary to bring about the reaction.As a demonstration experiment, opened bottles of concentrated ammonia and hydrochloric acid produce clouds of ammonium chloride, which seem to appear "out of nothing" as the salt forms where the two diffusing clouds of molecules meet, somewhere between the two bottles.The salts produced by the action of ammonia on acids are known as the ammonium salts and all contain the ammonium ion (NH4+).Although ammonia is well known as a weak base, it can also act as an extremely weak acid. It is a protic substance and is capable of formation of amides (which contain the NH2− ion). For example, lithium dissolves in liquid ammonia to give a solution of lithium amide: 2Li + 2NH3 → 2LiNH2 + H2 The combustion of ammonia in air is very difficult in the absence of a catalyst (such as platinum gauze or warm chromium(III) oxide), due to the relatively low heat of combustion, a lower laminar burning velocity, high auto-ignition temperature, high heat of vaporization, and a narrow flammability range. However, recent studies have shown that efficient and stable combustion of ammonia can be achieved using swirl combustors, thereby rekindling research interest in ammonia as a fuel for thermal power production.The flammable range of ammonia in dry air is 15.15%-27.35% and in 100% relative humidity air is 15.95%-26.55%.For studying the kinetics of ammonia combustion a detailed reliable reaction mechanism is required, however knowledge about ammonia chemical kinetics during combustion process has been challenging.In organic chemistry, ammonia can act as a nucleophile in substitution reactions. Amines can be formed by the reaction of ammonia with alkyl halides, although the resulting -NH2 group is also nucleophilic and secondary and tertiary amines are often formed as byproducts. An excess of ammonia helps minimise multiple substitution and neutralises the hydrogen halide formed. Methylamine is prepared commercially by the reaction of ammonia with chloromethane, and the reaction of ammonia with 2-bromopropanoic acid has been used to prepare racemic alanine in 70% yield. Ethanolamine is prepared by a ring-opening reaction with ethylene oxide: the reaction is sometimes allowed to go further to produce diethanolamine and triethanolamine.Amides can be prepared by the reaction of ammonia with carboxylic acid derivatives. Acyl chlorides are the most reactive, but the ammonia must be present in at least a twofold excess to neutralise the hydrogen chloride formed. Esters and anhydrides also react with ammonia to form amides. Ammonium salts of carboxylic acids can be dehydrated to amides so long as there are no thermally sensitive groups present: temperatures of 150–200 °C are required.The hydrogen in ammonia is susceptible to replacement by myriad substituents. When heated with sodium it converts to sodamide, NaNH2.With chlorine, monochloramine is formed.Pentavalent ammonia is known as λ5-amine or, more commonly, ammonium hydride. This crystalline solid is only stable under high pressure and decomposes back into trivalent ammonia and hydrogen gas at normal conditions. This substance was once investigated as a possible solid rocket fuel in 1966.Ammonia can act as a ligand in transition metal complexes. It is a pure σ-donor, in the middle of the spectrochemical series, and shows intermediate hard-soft behaviour (see also ECW model). Its relative donor strength toward a series of acids, versus other Lewis bases, can be illustrated by C-B plots.For historical reasons, ammonia is named ammine in the nomenclature of coordination compounds. Some notable ammine complexes include tetraamminediaquacopper(II) ([Cu(NH3)4(H2O)2]2+), a dark blue complex formed by adding ammonia to a solution of copper(II) salts. Tetraamminediaquacopper(II) hydroxide is known as Schweizer's reagent, and has the remarkable ability to dissolve cellulose. Diamminesilver(I) ([Ag(NH3)2]+) is the active species in Tollens' reagent. Formation of this complex can also help to distinguish between precipitates of the different silver halides: silver chloride (AgCl) is soluble in dilute (2M) ammonia solution, silver bromide (AgBr) is only soluble in concentrated ammonia solution, whereas silver iodide (AgI) is insoluble in aqueous ammonia.Ammine complexes of chromium(III) were known in the late 19th century, and formed the basis of Alfred Werner's revolutionary theory on the structure of coordination compounds. Werner noted only two isomers (fac- and mer-) of the complex [CrCl3(NH3)3] could be formed, and concluded the ligands must be arranged around the metal ion at the vertices of an octahedron. This proposal has since been confirmed by X-ray crystallography.An ammine ligand bound to a metal ion is markedly more acidic than a free ammonia molecule, although deprotonation in aqueous solution is still rare. One example is the Calomel reaction, where the resulting amidomercury(II) compound is highly insoluble.Ammonia forms 1:1 adducts with a variety of Lewis acids such as I2, phenol, and Al(CH3)3. Ammonia is a hard base and its E & C parameters are EB = 2.31 and C B = 2.04. Its relative donor strength toward a series of acids, versus other Lewis bases, can be illustrated by C-B plots.Ammonia and ammonium salts can be readily detected, in very minute traces, by the addition of Nessler's solution, which gives a distinct yellow colouration in the presence of the slightest trace of ammonia or ammonium salts. The amount of ammonia in ammonium salts can be estimated quantitatively by distillation of the salts with sodium or potassium hydroxide, the ammonia evolved being absorbed in a known volume of standard sulfuric acid and the excess of acid then determined volumetrically; or the ammonia may be absorbed in hydrochloric acid and the ammonium chloride so formed precipitated as ammonium hexachloroplatinate, (NH4)2PtCl6.The ancient Greek historian Herodotus mentioned that there were outcrops of salt in an area of Libya that was inhabited by a people called the "Ammonians" (now: the Siwa oasis in northwestern Egypt, where salt lakes still exist).The Greek geographer Strabo also mentioned the salt from this region. However, the ancient authors Dioscorides, Apicius, Arrian, Synesius, and Aëtius of Amida described this salt as forming clear crystals that could be used for cooking and that were essentially rock salt. Hammoniacus sal appears in the writings of Pliny, although it is not known whether the term is identical with the more modern sal ammoniac (ammonium chloride).The fermentation of urine by bacteria produces a solution of ammonia; hence fermented urine was used in Classical Antiquity to wash cloth and clothing, to remove hair from hides in preparation for tanning, to serve as a mordant in dying cloth, and to remove rust from iron.In the form of sal ammoniac, ammonia was important to the Muslim alchemists as early as the 8th century, first mentioned by the Persian-Arab chemist Jābir ibn Hayyān, and to the European alchemists since the 13th century, being mentioned by Albertus Magnus.It was also used by dyers in the Middle Ages in the form of fermented urine to alter the colour of vegetable dyes. In the 15th century, Basilius Valentinus showed that ammonia could be obtained by the action of alkalis on sal ammoniac.At a later period, when sal ammoniac was obtained by distilling the hooves and horns of oxen and neutralizing the resulting carbonate with hydrochloric acid, the name "spirit of hartshorn" was applied to ammonia.Gaseous ammonia was first isolated by Joseph Black in 1756 by reacting sal ammoniac (Ammonium Chloride) with calcined magnesia (Magnesium Oxide).It was isolated again by Peter Woulfe in 1767,by Carl Wilhelm Scheele in 1770 and by Joseph Priestley in 1773 and was termed by him "alkaline air".Eleven years later in 1785, Claude Louis Berthollet ascertained its composition.The Haber–Bosch process to produce ammonia from the nitrogen in the air was developed by Fritz Haber and Carl Bosch in 1909 and patented in 1910. It was first used on an industrial scale in Germany during World War I,following the allied blockade that cut off the supply of nitrates from Chile. The ammonia was used to produce explosives to sustain war efforts.Before the availability of natural gas, hydrogen as a precursor to ammonia production was produced via the electrolysis of water or using the chloralkali process.With the advent of the steel industry in the 20th century, ammonia became a byproduct of the production of coking coal.In the US as of 2019, approximately 88% of ammonia was used as fertilizers either as its salts, solutions or anhydrously.When applied to soil, it helps provide increased yields of crops such as maize and wheat.30% of agricultural nitrogen applied in the US is in the form of anhydrous ammonia and worldwide 110 million tonnes are applied each year.Ammonia is directly or indirectly the precursor to most nitrogen-containing compounds. Virtually all synthetic nitrogen compounds are derived from ammonia. An important derivative is nitric acid. This key material is generated via the Ostwald process by oxidation of ammonia with air over a platinum catalyst at 700–850 °C (1,292–1,562 °F), ≈9 atm. Nitric oxide is an intermediate in this conversion: NH3 + 2 O2 → HNO3 + H2O Household ammonia is a solution of NH3 in water, and is used as a general purpose cleaner for many surfaces. Because ammonia results in a relatively streak-free shine, one of its most common uses is to clean glass, porcelain and stainless steel. It is also frequently used for cleaning ovens and soaking items to loosen baked-on grime. Household ammonia ranges in concentration by weight from 5 to 10% ammonia.United States manufacturers of cleaning products are required to provide the product's material safety data sheet which lists the concentration used.As early as in 1895, it was known that ammonia was "strongly antiseptic ... it requires 1.4 grams per litre to preserve beef tea." In one study, anhydrous ammonia destroyed 99.999% of zoonotic bacteria in 3 types of animal feed, but not silage.Anhydrous ammonia is currently used commercially to reduce or eliminate microbial contamination of beef.Lean finely textured beef (popularly known as "pink slime") in the beef industry is made from fatty beef trimmings (c. 50–70% fat) by removing the fat using heat and centrifugation, then treating it with ammonia to kill E. coli. The process was deemed effective and safe by the US Department of Agriculture based on a study that found that the treatment reduces E. coli to undetectable levels.There have been safety concerns about the process as well as consumer complaints about the taste and smell of beef treated at optimal levels of ammonia.The level of ammonia in any final product has not come close to toxic levels to humans.Because of ammonia's vaporization properties, it is a useful refrigerant.It was commonly used before the popularisation of chlorofluorocarbons (Freons). Anhydrous ammonia is widely used in industrial refrigeration applications and hockey rinks because of its high energy efficiency and low cost. It suffers from the disadvantage of toxicity, and requiring corrosion resistant components, which restricts its domestic and small-scale use. Along with its use in modern vapor-compression refrigeration it is used in a mixture along with hydrogen and water in absorption refrigerators. The Kalina cycle, which is of growing importance to geothermal power plants, depends on the wide boiling range of the ammonia–water mixture. Ammonia coolant is also used in the S1 radiator aboard the International Space Station in two loops which are used to regulate the internal temperature and enable temperature dependent experiments.The potential importance of ammonia as a refrigerant has increased with the discovery that vented CFCs and HFCs are extremely potent and stable greenhouse gases.The contribution to the greenhouse effect of CFCs and HFCs in current use, if vented, would match that of all CO2 in the atmosphere.The raw energy density of liquid ammonia is 11.5 MJ/L,which is about a third that of diesel. There is the opportunity to convert ammonia back to hydrogen, where it can be used to power hydrogen fuel cells or directly within high-temperature fuel cells.The conversion of ammonia to hydrogen via the sodium amide process,either for combustion or as fuel for a proton exchange membrane fuel cell,is possible. Conversion to hydrogen would allow the storage of hydrogen at nearly 18 wt% compared to ≈5% for gaseous hydrogen under pressure.Ammonia engines or ammonia motors, using ammonia as a working fluid, have been proposed and occasionally used.The principle is similar to that used in a fireless locomotive, but with ammonia as the working fluid, instead of steam or compressed air. Ammonia engines were used experimentally in the 19th century by Goldsworthy Gurney in the UK and the St. Charles Avenue Streetcar line in New Orleans in the 1870s and 1880s,and during World War II ammonia was used to power buses in Belgium.Ammonia is sometimes proposed as a practical alternative to fossil fuel for internal combustion engines.Its high octane rating of 120 and low flame temperature allows the use of high compression ratios without a penalty of high NOx production. Since ammonia contains no carbon, its combustion cannot produce carbon dioxide, carbon monoxide, hydrocarbons, or soot.Even though ammonia production currently creates 1.8% of global CO2 emissions, the Royal Society report claims that "green" ammonia can be produced by using low-carbon hydrogen (blue hydrogen and green hydrogen). Total decarbonization of ammonia production and the accomplishment of net-zero targets are possible by 2050.However ammonia cannot be easily used in existing Otto cycle engines because of its very narrow flammability range, and there are also other barriers to widespread automobile usage. In terms of raw ammonia supplies, plants would have to be built to increase production levels, requiring significant capital and energy sources. Although it is the second most produced chemical (after sulfuric acid), the scale of ammonia production is a small fraction of world petroleum usage. It could be manufactured from renewable energy sources, as well as coal or nuclear power. The 60 MW Rjukan dam in Telemark, Norway produced ammonia for many years from 1913, providing fertilizer for much of Europe.Despite this, several tests have been done. In 1981, a Canadian company converted a 1981 Chevrolet Impala to operate using ammonia as fuel.In 2007, a University of Michigan pickup powered by ammonia drove from Detroit to San Francisco as part of a demonstration, requiring only one fill-up in Wyoming.Compared to hydrogen as a fuel, ammonia is much more energy efficient, and could be produced, stored, and delivered at a much lower cost than hydrogen which must be kept compressed as a cryogenic liquid.Rocket engines have also been fueled by ammonia. The Reaction Motors XLR99 rocket engine that powered the X-15 hypersonic research aircraft used liquid ammonia. Although not as powerful as other fuels, it left no soot in the reusable rocket engine, and its density approximately matches the density of the oxidizer, liquid oxygen, which simplified the aircraft's design.Ammonia, as the vapor released by smelling salts, has found significant use as a respiratory stimulant. Ammonia is commonly used in the illegal manufacture of methamphetamine through a Birch reduction.The Birch method of making methamphetamine is dangerous because the alkali metal and liquid ammonia are both extremely reactive, and the temperature of liquid ammonia makes it susceptible to explosive boiling when reactants are added.Liquid ammonia is used for treatment of cotton materials, giving properties like mercerisation, using alkalis. In particular, it is used for prewashing of wool.At standard temperature and pressure, ammonia is less dense than atmosphere and has approximately 45-48% of the lifting power of hydrogen or helium. Ammonia has sometimes been used to fill weather balloons as a lifting gas. Because of its relatively high boiling point (compared to helium and hydrogen), ammonia could potentially be refrigerated and liquefied aboard an airship to reduce lift and add ballast (and returned to a gas to add lift and reduce ballast).The U.S. Occupational Safety and Health Administration (OSHA) has set a 15-minute exposure limit for gaseous ammonia of 35 ppm by volume in the environmental air and an 8-hour exposure limit of 25 ppm by volume.The National Institute for Occupational Safety and Health (NIOSH) recently reduced the IDLH (Immediately Dangerous to Life and Health, the level to which a healthy worker can be exposed for 30 minutes without suffering irreversible health effects) from 500 to 300 based on recent more conservative interpretations of original research in 1943. Other organizations have varying exposure levels. U.S. Navy Standards [U.S. Bureau of Ships 1962] maximum allowable concentrations (MACs): continuous exposure (60 days): 25 ppm / 1 hour: 400 ppm.Ammonia vapour has a sharp, irritating, pungent odour that acts as a warning of potentially dangerous exposure. The average odour threshold is 5 ppm, well below any danger or damage. Exposure to very high concentrations of gaseous ammonia can result in lung damage and death.Ammonia is regulated in the United States as a non-flammable gas, but it meets the definition of a material that is toxic by inhalation and requires a hazardous safety permit when transported in quantities greater than 13,248 L (3,500 gallons).Liquid ammonia is dangerous because it is hygroscopic and because it can cause caustic burns. See Gas carrier § Health effects of specific cargoes carried on gas carriers for more information.The toxicity of ammonia solutions does not usually cause problems for humans and other mammals, as a specific mechanism exists to prevent its build-up in the bloodstream. Ammonia is converted to carbamoyl phosphate by the enzyme carbamoyl phosphate synthetase, and then enters the urea cycle to be either incorporated into amino acids or excreted in the urine.Fish and amphibians lack this mechanism, as they can usually eliminate ammonia from their bodies by direct excretion. Ammonia even at dilute concentrations is highly toxic to aquatic animals, and for this reason it is classified as dangerous for the environment.Ammonia is a constituent of tobacco smoke.Ammonia is present in coking wastewater streams, as a liquid by-product of the production of coke from coal.In some cases, the ammonia is discharged to the marine environment where it acts as a pollutant. The Whyalla steelworks in South Australia is one example of a coke-producing facility which discharges ammonia into marine waters.
AMMONIUM ACETATE
AMMONIUM ACETATE Ammonium acetate(Amonyum asetat), also known as spirit of Mindererus in aqueous solution, is a chemical compound with the formula NH4CH3CO2. It is a white, hygroscopic solid and can be derived from the reaction of ammonia and acetic acid. It is available commercially.[5] Contents 1 Uses 1.1 Buffer 1.2 Other 1.3 Food additive 2 Production 3 References 4 External links Uses It is the main precursor to acetamide:[6] NH4CH3CO2 → CH3C(O)NH2 + H2O It is also used as a diuretic.[5] Buffer As the salt of a weak acid and a weak base, Ammonium acetate(Amonyum asetat) is often used with acetic acid to create a buffer solution. Ammonium acetate(Amonyum asetat) is volatile at low pressures. Because of this, it has been used to replace cell buffers with non-volatile salts in preparing samples for mass spectrometry.[7] It is also popular as a buffer for mobile phases for HPLC with ELSD detection for this reason. Other volatile salts that have been used for this include Ammonium acetate(Amonyum asetat) formate. Other a biodegradable de-icing agent. a catalyst in the Knoevenagel condensation and as a source of ammonia in the Borch reaction in organic synthesis. a protein precipitating reagent in dialysis to remove contaminants via diffusion. a reagent in agricultural chemistry for determination of soil CEC (cation exchange capacity ) and determination of available potassium in soil wherein the Ammonium acetate(Amonyum asetat) ion acts as a replacement cation for potassium. Food additive Ammonium acetate(Amonyum asetat) is also used as a food additive as an acidity regulator; INS number 264. It is approved for usage in Australia and New Zealand.[8] Production Ammonium acetate(Amonyum asetat) is produced by the neutralization of acetic acid with Ammonium acetate(Amonyum asetat) carbonate or by saturating glacial acetic acid with ammonia.[9] Obtaining crystalline Ammonium acetate(Amonyum asetat) is difficult on account of its hygroscopic nature. Ammonium acetate(Amonyum asetat) PORPHYRINS: LIQUID CHROMATOGRAPHY Choice of Mobile Phase The porphyrins derived from the haem biosynthetic pathway are amphoteric compounds ionizable and soluble in both acids and bases. They are therefore ideal for separation by RP-HPLC in the presence of an ion-pairing agent (e.g. tetrabutyl Ammonium acetate(Amonyum asetat) phosphate) or by ionization control with an acid (e.g. trifluoroacetic acid), a base (e.g. triethylamine) or a buffer solution (e.g. Ammonium acetate(Amonyum asetat) buffer). The choice of a correct mobile phase is obviously important for achieving an optimal separation. With the increasing use of online HPLC–mass spectrometry (LC–MS), the chosen mobile phase ideally should also be fully compatible with mass spectrometry. The introduction of hybrid electrospray quadrupole/time-of-flight MS allows sensitive and specific analysis of porphyrin free acids by LC–MS. To exploit this capability a mobile phase that is sufficiently volatile and is able to separate the whole range of porphyrins, including the complex type-isomers, is highly desirable. This rules out reversed-phase ion pair chromatography and the use of phosphate buffer. Simple acidic eluent such as 0.1% trifluoroacetic acid–acetonitrile mixtures can be used for the separation of porphyrins. However, resolution of the type-isomers of uro- and hepta-carboxyl porphyrins was not achieved although type-isomers of porphyrins with 6, 5, and 4 carboxyl groups were well separated. To date, mobile phases containing Ammonium acetate(Amonyum asetat) buffer provide excellent resolution and column efficiency as well as being fully compatible with LC–MS operation. This buffer has been studied for the separation of porphyrins in detail and the following conclusions have been drawn: The molar concentration of Ammonium acetate(Amonyum asetat) buffer in the mobile phase significantly affected the retention and resolution. The optimum buffer concentration is 1 M. Below 0.5 M, excessive retention and peak broadening results, particularly in isocratic elution. At above 1.5 M, rapid elution with the consequent loss of resolution was observed. The retention and resolution of the porphyrins are greatly influenced by the pH of the Ammonium acetate(Amonyum asetat) buffer. Increasing the pH decreased the retention with loss of resolution. The optimum pH range is between 5.1 and 5.2, although this is column dependent. This pH range is, however, suitable for most reversed-phase columns. In earlier studies it was shown that the isocratic elution of uroporphyrin I and III from reversed-phase columns was organic modifier specific and, with methanol as the organic modifier and 1 M Ammonium acetate(Amonyum asetat) (pH 5.16) as the aqueous buffer, excessive retention and peak broadening was observed. The methanol adsorbed on the hydrocarbonaceous stationary phase surface is able to form extensive hydrogen bonds with the eight carboxyl groups of uroporphyrin, thus resulting in long retention and peak broadening. This effect is less significant in the separation of porphyrins with fewer carboxyl groups. Nevertheless it is best to avoid using methanol as the sole organic modifier in porphyrin separations, especially when uroporphyrin is one of the components to be separated. Replacing methanol with acetonitrile results in excellent resolution of uroporphyrin isomers within convenient retention times. Acetonitrile, however, is immiscible with 1 M Ammonium acetate(Amonyum asetat) when its proportion is above 35% in the mobile phase. While acetonitrile–1 M Ammonium acetate(Amonyum asetat) buffer mobile phase systems are excellent for the separation of porphyrins that can be eluted at up to 30% acetonitrile content (8-, 7-, 6-, 5- and 4-carboxyl porphyrins), they are not suitable for the separation of porphyrins that required a higher proportion of acetonitrile for elution, such as the dicarboxyl mesoporphyrin and protoporphyrin. In order to achieve simultaneous separation of all the porphyrins, therefore, a mixture of acetonitrile and methanol as the organic modifier is required. 1 M Ammonium acetate(Amonyum asetat) buffer is completely miscible with methanol. A mixture consisting of 9–10% (v/v) acetonitrile in methanol as the organic modifier thus overcomes the hydrogen bonding effect caused by methanol and the solubility problem of 1 M Ammonium acetate(Amonyum asetat) in acetonitrile. In practice, gradient elution is carried out by inclusion of 10% (v/v) acetonitrile in each of the gradient solvents, i.e. 1 M Ammonium acetate(Amonyum asetat) (pH 5.16) and methanol. Ammonium acetate(Amonyum asetat) solution, 5M is an important reagent for studying molecular biology, biological buffers, reagents and DNA and RNA purification. It is a popular buffer for mobile phases for HPLC with ESLD detection, for ESI mass spectrometry of proteins and other molecules, and has been used to replace cell buffers with non-volitile salts. Ammonium acetate(Amonyum asetat) is also used in protein studies and protein preparation. It can be used in the protein purification steps of dialysis to remove contaminants through diffusion and, when combined with distilled water, as a protein precipitating agent. In organic chemistry, Ammonium acetate(Amonyum asetat) solution is useful as a catalyst in the Knoevenagel condensation and as a source of ammonia in the Borch reaction. Additionally, it is occasionally used commercially as a biodegradable de-icing agent and as an additive in food as an acidity regulator. How long does 10M Ammonium acetate(Amonyum asetat) take to dissolve in water? I need to make 10M Ammonium acetate(Amonyum asetat) for DNA extraction. I calculated the amount required for 70 ml solution and started dissolving it using a magnetic stirrer. It has been four hours, but the solute hasn't dissolved yet. Is this normal? How long does it usually take to make 10M Ammonium acetate(Amonyum asetat) solution? The Ammonium acetate(Amonyum asetat) I used to make solution was not powder per se, it was more like crystals. I cannot add more water to the solution. Is heating an option? I am trying to make acetonitrile solution containing 10mM Ammonium acetate(Amonyum asetat), but I've noticed that Ammonium acetate(Amonyum asetat) would immediately crash out once 10ml of 1M stock was added into 1L acetonitril. This solution will be used as a mobile phase in LC-MS-MS for gradient elution, so ideally acetonitrile concentration should be kept at no less than 98%. Does anyone have experience making up this solution? I want to prepare 7.5 M Ammonium acetate(Amonyum asetat) solution. The recipe stated that I need to dissolved 57.81 g Ammonium acetate(Amonyum asetat) in water to final volume of 100 ml, then sterilize by filtration (0.2 micro meter filter). The final pH will be 5.5. I don't understand and don't know how to sterilize by filtration? I hope someone can explain and show how to prepare this solution. Thank you Our 5M Ammonium acetate(Amonyum asetat) solution is prepared in molecular biology grade/ultrapure water, filter sterilized with 0.22 µm filter and DNase/RNase/Protease Free. Ammonium acetate(Amonyum asetat) solution is an important reagent used in molecular biology research- DNA and RNA purification, biological buffers, chemical analysis, in pharmaceuticals, and in preserving foods. It is commonly used for routine precipitation of nucleic acids, and is useful for reducing the co-precipitation of unwanted dNTPs and contaminating oligosaccharides in the sample. Note: 1) Ammonium acetate(Amonyum asetat) should not be used when phosphorylating the nucleic acid using T4 polynucleotide kinase, because this enzyme is inhibited by Ammonium acetate(Amonyum asetat) ions. 2) Do not autoclave Ammonium acetate(Amonyum asetat) Acetate Buffer. If precipitates form, warm solution to 37°C to re-suspend. Ammonium acetate(Amonyum asetat) is also used in protein studies and protein preparation. It can be used in the protein purification steps of dialysis to remove contaminants through diffusion and, when combined with distilled water, as a protein precipitating agent. It is a popular buffer for mobile phases for HPLC with ESLD detection, for ESI mass spectrometry of proteins and other molecules, and has been used to replace cell buffers with non-volatile salts. Ammonium acetate(Amonyum asetat) solution is used commercially as a biodegradable de-icing agent and as an additive in food. Additionally, it is useful in organic chemistry as a catalyst in the Knoevenagel condensation and as a source of ammonia in the Borch reaction. The chemical details of Ammonium acetate(Amonyum asetat) are below: CAS Number: 631-61-8; Synonyms: Azanium Acetate; Acetic acid Ammonium acetate(Amonyum asetat) salt; Acetic acid, Ammonium acetate(Amonyum asetat) salt; Ammonium acetate(Amonyum asetat) ethanoate Molecular Formula: C2H7NO2 Molecular Weight: 77.083 g/mol InChI Key: USFZMSVCRYTOJT-UHFFFAOYSA-N Product Description Ammonium acetate(Amonyum asetat) Application Notes Ammonium acetate(Amonyum asetat) Ultra pure is for applications which require tight control of elemental content. Ammonium acetate(Amonyum asetat) is a widely used reagent in molecular biology and chromatography. Its applications include the purification and precipitation of DNA and protein crystallization. Ammonium acetate(Amonyum asetat) is commonly used in HPLC and MS analysis of various compounds, such as oligosaccharides, proteins, and peptides. Ammonium acetate(Amonyum asetat) is also used for the nonaqueous capillary electrophoresis-mass spectrometry (NACE-MS) of lipophilic peptides and therapeutic drugs. Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. Applications Ammonium acetate(Amonyum asetat) is widely utilized as a catalyst in the Knoevenagel condensation. It is the primary source of ammonia in the Borch reaction in organic synthesis. It is used with distilled water to make a protein precipitating reagent. It acts as a buffer for electrospray ionization (ESI) mass spectrometry of proteins and other molecules and as mobile phases for high performance liquid chromatography (HPLC). Sometimes, it is used as a biodegradable de-icing agent and an acidity regulator in food additives. Notes Hygroscopic. Incompatible with strong oxidizing agents and strong acids. Ammonium acetate(Amonyum asetat) Ammonium acetate(Amonyum asetat) is an inorganic chemical compound. Its IUPAC name is Ammonium acetate(Amonyum asetat) ethanoate. When in aqueous solution, the substance is often called spirit of Mindererus. Ammonium acetate(Amonyum asetat) CAS number is 631-61-8, its chemical formula can be written in two ways: C2H7NO2 and NH4CH3CO2. The compound itself is a white solid with orthorhombic crystal structure and highly hygroscopic. It dissolves easily in cold water and decomposes in hot. Besides, Ammonium acetate(Amonyum asetat) is soluble in alcohol, acetone, sulfur dioxide, and liquid ammonia. Here are some more characteristics of the substance: density: 1.17 g/cm3; molar mass: 77.08 g·mol−1; melting point: 113 °C; flash point: 136 °C. The chemical is considered hazardous, as it irritates human tissues. Production and Uses There are two methods of Ammonium acetate(Amonyum asetat) production. According to the first one, acetic acid is neutralized with Ammonium acetate(Amonyum asetat) carbonate. The second includes saturation of glacial acetic acid with ammonia. Ammonium acetate(Amonyum asetat) uses are not very diverse. It usually serves as basic catalyst for Henry reactions. The substance is also used to create a buffer solution, since it is the salt of a weak acid. It is an important reagent in different chemical reactions. In food industry, the compound is applied to control the acidity and alkalinity of foods. You do not need now to spend your precious time on searching consumables for your lab as you can buy Ammonium acetate(Amonyum asetat) and many other chemicals at compatible price on our website Brumer.com. We care about our customers and offer you only certified high-quality products for your laboratory needs. Ammonium acetate(Amonyum asetat) Formula Ammonium acetate(Amonyum asetat) Ammonium acetate(Amonyum asetat) Formula- It is a salt that has interesting chemical properties and due to this reason, the pharmaceutical industry uses it as an intermediary and raw material in various processes. NH4OAc (Ammonium acetate(Amonyum asetat)) is a salt that forms from the reaction of ammonia and acetic acid. Also, it is useful for applications that require buffer solutions. The Henry reactions are the most common reactions that use Ammonium acetate(Amonyum asetat). In an aqueous solution, it is a chemical compound that we know by the name spirit of Mindererus or Ammonium acetate(Amonyum asetat), which is a white, hygroscopic solid we can derive from the reaction of ammonia and acetic acid. Ammonium acetate(Amonyum asetat) Formula and Structure Its chemical formula is NH4CH2CO2 or CH2COONH4. The molecular formula of Ammonium acetate(Amonyum asetat) is C2H7NO2and its molar mass is 77.08 g/mol-1. Also, it is a slat of acetate ion COO-1(from acetic acid dissociation in water) and Ammonium acetate(Amonyum asetat) ion NH4+(from ammonia dissociation in water). Ammonium acetate(Amonyum asetat) is volatile at low pressure because it has been used to replace cell buffers with non-volatile salts that help in the preparation of chemical samples. Its common representation of organic molecule’s chemical structure can be written as below: Ammonium acetate(Amonyum asetat) formula Ammonium acetate(Amonyum asetat) Occurrence In nature, Ammonium acetate(Amonyum asetat) is not present in a free compound state. But, Ammonium acetate(Amonyum asetat) and acetate ions are present in many biochemical processes. Ammonium acetate(Amonyum asetat) Preparation Just like other acetates, we can also synthesize Ammonium acetate(Amonyum asetat) in a similar way to other acetates that is through neutralization of acetic acid. Furthermore, this synthesis uses acetic acid that we neutralize by adding Ammonium acetate(Amonyum asetat) carbonate. Besides, in the chemical industries, this method uses glacial acetic acid that is saturated with ammonia: 2CH3COOH + (NH4)2CO3→ 2CH3COONH4+ H2CO3 H2CO3→ CO2+ H2O CH3COOH + NH3→ CH3COONH4 Ammonium acetate(Amonyum asetat) Physical Properties It is a hygroscopic white solid with a slightly acidic odor. Furthermore, its melting point is 113oC. Also, it is highly soluble in water and its density in this liquid is 1.17 g/mL-1. Ammonium acetate(Amonyum asetat) Chemical Properties It is a slat of a weak acid (acetic acid) and a weak base (ammonia). We use this salt with acetic acid to prepare a buffer solution to regulate its pH. Nevertheless, its use as a buffering agent is not very extensive because Ammonium acetate(Amonyum asetat) can be volatile in low pressures. Ammonium acetate(Amonyum asetat) Uses We use it as a raw material in the synthesis of pesticides, herbicides, and non-steroidal anti-inflammatory drugs. Moreover, it is the precursor in the acetamide synthesis (a chemical compound that we use to produce plasticizers): CH3COONH4→ CH3C(O)NH2+ H2O In industries, they use it to acidify textiles and hair and some countries use it as a food acidity regulator. With acetic acid, it is a buffering agent. In organic chemistry, Ammonium acetate(Amonyum asetat) found its use as a catalyst, in reactions such as Knoevenagel condensations. We can use it as a fertilizer and in the synthesis of explosives. It is volatile at low pressure and because of this, industries and scientists have used it to replace cell buffers with non-volatile salts in preparing samples for mass spectrometry. Besides, it is popular as a buffer for mobile phases for HPLC and ELSD detection for this reason. Moreover, other salts that they have used for this include Ammonium acetate(Amonyum asetat) formate. Ammonium acetate(Amonyum asetat) Health and Safety Hazards Majorly, Ammonium acetate(Amonyum asetat) causes irritation in the mouth, eyes, skin, and nose. Furthermore, it is highly dangerous by ingestion and can cause tissue necrosis. It can also destroy the cell membranes, penetrate in organisms, and saponify the skin. When heated it produces toxic fumes that can damage the lungs. In a few seconds, it can decompose sodium hypochlorite. Solved Examples on Ammonium acetate(Amonyum asetat) Formula Question: Show how Ammonium acetate(Amonyum asetat) is a precursor of acetamide? Solution: The reaction is as below: NH4CH3CO2 → CH3C(O)NH2 + H2O 11.4.3 Reagents and Materials Acetonitrile, methanol: HPLC grade; n-Hexane; Ammonium acetate(Amonyum asetat) hydroxide; Formic acid; Ammonium acetate(Amonyum asetat); Anhydrous sodium sulfate: Calcine at 650°C for 4 h and store in a desiccator; Ammonium acetate(Amonyum asetat) hydroxide-methanol mixed solvent: 25 + 75,v/v; Formic acid solution: 0.1%; Ammonium acetate(Amonyum asetat) buffer solution: 10 mmol/L; Strong cation exchange (SCX) SPE cartridge: 500 mg/3 mL; the extraction cartridge is conditioned using 3 mL methanol, 3 mL water, 3 mL 10 mmol/L ammonia acetate before use. Prevent the columns from running dry. Ammonium acetate(Amonyum asetat) Acetonitrile: HPLC grade. Chlorhydric acid Tris hydroxymethylaminomethane (tris): C4H11NO3 Calcium chloride: CaCl2·2H2O. Methanol water solution (2 + 3): Mix 400 mL methanol and 600 mL water. 0.01 mol/L Ammonium acetate(Amonyum asetat) solution: Dissolve 0.77 g Ammonium acetate(Amonyum asetat) into a 1000-mL volumetric flask, bring to volume with water and mix. Constant volume solution: Mix 0.01 mol/L Ammonium acetate(Amonyum asetat) solution and Acetonitrile in volume proportion of 17:3. Ammonium acetate(Amonyum asetat): Analytically Pure Methanol: HPLC Grade Toluene: HPLC Grade Acetone: HPLC Grade Sodium Acetate: Anhydrous, Analytically Pure Membrane Filters (Nylon): 13 mm × 0.2 μm, 13 mm × 0.45 μm Sodium Sulfate, Magnesium Sulfate: Anhydrous, Analytically Pure. Ignited at 650°C for 4 h and Kept in a Desiccator 0.1% Formic Acid (V/V) 5 mmol/L Ammonium acetate(Amonyum asetat) Solution Ammonium acetate(Amonyum asetat), sulphate or phosphate which liberates respective acid beyond 80°C to develop required pH. Dye anions possess higher affinity for fibre even at neutral pH requiring a minimum of acid. These are commonly known as ‘super milling dyes’ due to their high fastness to milling. Dyeing is started at 60°C with Ammonium acetate(Amonyum asetat) Ammonium acetate(Amonyum asetat) is a widely used reagent in molecular biology and chromatography. Suitable applications include the purification and precipitation of DNA and protein crystallization. Ammonium acetate(Amonyum asetat) is commonly used in HPLC and MS analysis of various compounds, such as oligosaccharides, proteins, and peptides. Based on the experimental results obtained with the analogue Fumaric Acid (4h-LD 50 for New Zealand rabbits > 20000 mg/kg bw) and the molecular weights, the read-across approach is applied and the LD 50 for substance Ammonium acetate(Amonyum asetat) is calculated to be greater than 26556.42 mg/kg bw under test conditions. The analogue Fumaric Acid, which shares the same functional group with Ammonium acetate(Amonyum asetat), also has comparable values for the relevant molecular properties. These properties are: - a low log Pow value which is 0.25 for Fumaric Acid and - 2.79 for Ammonium acetate(Amonyum asetat), - water solubility which is 0.0063 g/mL at 25 ºC for Fumaric Acid and 1480 g/L at 4 ºC for Ammonium acetate(Amonyum asetat), and - molecular weights which are 116.07 for Fumaric Acid and 77.08 for Ammonium acetate(Amonyum asetat). Any other information on results incl. tables The analogue Fumaric Acid which shares the same functional group with Ammonium acetate(Amonyum asetat), also has comparable values for the relevant molecular properties. These properties are: - a low log Pow value which is 0.25 for Fumaric Acid and -2.79 for Ammonium acetate(Amonyum asetat), - similar molecular weights which are 116.07 for Fumaric Acid and 77.08 for Ammonium acetate(Amonyum asetat). Both chemicals are grouped together by US EPA category group Carboxylic Food Acids and Salts Category. As indicated in the European Chemical Agency Practical Guide 6 “How to report read –across and categories”, the structural grouping was realized using “OECD QSAR APPLICATION TOOL BOX” version 1.1.0.Presented results show that both substances have common (eco)toxicological behavior (attachment). Ammonium acetate(Amonyum asetat) ENVIRONMENTAL FATE and PATHWAY Aerobic Biodegradation Experimental results: Readily biodegradable Experimental results on Ammonium acetate(Amonyum asetat), read-across from experimental data on Sodium Acetate and read-across from estimated data on Ammonia and Acetic Acid, based on functional group: Experimental data and read-across from Potassium Acetate, based on molecular weights: Acute Toxicity to Aquatic Invertebrates Experimental data: Read-across from experimental data on analogues Sodium Acetate, Potassium Acetate and Ammonia, based on molecular weights: Read-across from experimental data on analogues Acetic Acid, Potassium Acetate and Ammonium acetate(Amonyum asetat) Sulphate, based on molecular weights: Acute Toxicity: Oral Experimental data: Weight of evidence: Read-across from experimental data on Potassium Acetate and Ammonium acetate(Amonyum asetat) Sulphate, based on molecular weights: Weight of evidence: Read-across from experimental data on Fumaric Acid and Ammonium acetate(Amonyum asetat) Sulphate, based on molecular weights: Weight of evidence: Read-across approach from experimental data on analogues Potassium Acetate and Ammonium acetate(Amonyum asetat) Lactate, and Ammonium acetate(Amonyum asetat) Stearate based on functional group: The substance Ammonium acetate(Amonyum asetat) is considered as not irritating for skin. Eye Irritation/Corrosion Experimental data: Fumaric Acid has been tested by application of a drop of 10% solution to the eyes of rabbits after mechanical removal of corneal epithelium to facilitate penetration, but it appeared to do no damage, & healing was similar to that in control eyes without test chemical. Weight of evidence: Read-across approach from experimental data on analogues Potassium Acetate, Ammonium acetate(Amonyum asetat) Sulphate, and Ammonium acetate(Amonyum asetat) Stearate, based on functional group: The substance Ammonium acetate(Amonyum asetat) is considered as not irritating for eyes. Weight of evidence: Read-across approach from experimental results on Citric Acid, Glycolic Acid, Sodium Glycolate, Lactic Acid, Ammonium acetate(Amonyum asetat) Lactate, and Triacetin, based on functional group: All this substances were not sensitising for human and guinea pigs. Based on these results, Ammonium acetate(Amonyum asetat) is considered to be not sensitizing. Repeated Dose Toxicity Repeated dose toxicity: oral: Experimental data: Repeated dose toxicity: oral: 2-year study in male and female rats which were treated by diet. The LOAEL = 750 mg/kg bw/day (based on slight increases in mortality and increased incidence of testes degeneration at the highest dose tested). The NOAEL = 600 mg/kg bw/day. Repeated dose toxicity: oral: Weight of evidence: Experimental results: Repeated dose toxicity: oral: 90 days withfemale Wistar rats. The NOAEL was 3150.4 mg/kg bw/day . Repeated dose toxicity: oral: 15 days study with female Wistar rats. The NOAEL 3102.2 mg/kg bw/day . Read-across from the analogue Sodium Acetate, based on molecular weights: In a bacterial reverse mutation assay usingS. typhimurium(TA98, TA100, TA1535, TA97 and TA1537) in the absence of metabolic activation and concentrations up to 1000μg/plate, fumaric acid was not mutagenic. Weight of evidence: Read-across from Sodium Acetate (category analogue) based on functional group: Reverse mutation assay using S. typhimurium strains TA92, TA1535, TA100, TA1537, TA94 and TA98 with metabolic activation. Resultslead to the conclusion that Ammonium acetate(Amonyum asetat) did not cause point mutations in the microbial systems. Read-across from Acetic Acid, based on functional group: Ammonium acetate(Amonyum asetat) is considered to be not mutagenic on S.typhimurium TA 98, TA 100, TA 1535, TA 97, and/or TA 1537, with and without metabolic activation. Read-across from experimental data on Ammonia, anhydrous, based on functional group: Ammonium acetate(Amonyum asetat) is considered to be not mutagenic on Salmonella typhimurium TA 98, TA 100, TA 1535, TA 1537, and TA 1538, and Escherichia coli WP2uvrA, with and without metabolic activation. Read-across from experimental data on Ammonia, aqueous solution, based on functional group: Ammonium acetate(Amonyum asetat) is considered not mutagenic on E. coli Sd-4-73, without metabolic activation. Weight of evidence: Read-across from the analogue Acetic anhydride, based on functional group: Ammonium acetate(Amonyum asetat) is considered to be not mutagenic on mouse lymphoma L5178Y cells, with and without metabolic activation. Read-across from the analogue Phenoxy acetic acid, based on functional group: Ammonium acetate(Amonyum asetat) is considered to be not mutagenic on Chinese hamster ovary cells, with and without metabolic activation. Estimated data from Danish (Q)SAR Database: Ammonium acetate(Amonyum asetat) was not mutagenic in mammalian cell gene mutation assays on mouse lymphoma L5178Y cells nor on Chinese hamster ovary cells. Chromosomal aberration Fumaric acid was assayed in anin vitroassay using Chinese hamster fibroblast cells in the absence of metabolic activation at doses up to 1 mg/mL; however, insufficient information was provided in the robust summary to adequately evaluate this study. Weight of evidence: Read-across from Sodium Acetate (category analogue) based on functional group: In an in vitro chromosomal aberration assay with a Chinese hamster fibroblast cell line, CHL, without metabolic activation systems, it is concluded that Ammonium acetate(Amonyum asetat) did not induce chromosomal aberrations(including gaps). Read-across from Acetic Acid, based on functional group: Ammonium acetate(Amonyum asetat) is considered as not clastogenic on Chinese hamster Ovary (CHO) cells, without metabolic activation. Read-across from Ammonium acetate(Amonyum asetat) Sulfate, based on functional group: Ammonium acetate(Amonyum asetat) is not considered mutagenic on Chinese Hamster Ovary cells, in the absence of a metabolic activation system. Key studies: Read-across from Sodium Acetate (category analogue) based on functional group: The Testicular DNA-synthesis inhibition test (DSI test) on male mice provides evidence that Ammonium acetate(Amonyum asetat) is not genotoxic in animals (basis of the method: measuring 3H-thymidine incorporation). Test substance did not inhibit DNA replication in this assay. TOXICITY TO REPRODUCTION: Weight of evidence: Read-across from the analogue Citric Acid, based on molecular weights: A study on rats and mice daily treated by feed before, during, and after mating. For Ammonium acetate(Amonyum asetat), the NOAEL is calculated to be equal or greater than 3009.37 mg/kg bw/day (basis for effect: number of pregnancies, number of young born, or survival of young). A fertility test on female rats daily treated by feed for several months. For Ammonium acetate(Amonyum asetat), the NOAEL is calculated to be 722.25 mg/kg bw/day, and LOAEL greater than 722.25 mg/kg bw/day for reproductive effects. Read-across from the analogue Citric Acid, sodium salt, based on molecular weights: A fertility study on female rats daily treated by feed for several months. For Ammonium acetate(Amonyum asetat), the NOAEL is calculated to be 54.0 mg/kg bw/day, and LOAEL greater than 54.0 mg/kg bw/day for reproductive effects. Read-across from the analogue Ammonium acetate(Amonyum asetat) sulfate, based on molecular weights: A study on male and female rats exposed for 13 weeks to diets with Ammonium acetate(Amonyum asetat) Sulfate. For Ammonium acetate(Amonyum asetat), the NOAEL is calculated to be 1033.64 mg/kg bw/day for males, and 2304.12 mg/kg bw/day for females. DEVELOPMENTAL TOXICITY / TERATOGENICITY: Weight of evidence: Experimental results: A study on female rats fed an Ammonium acetate(Amonyum asetat) -containing diet starting on day 1 of pregnancy until weaning (at posnatal day on 21). After weaning, pups were either fed a normal diet, with no Ammonium acetate(Amonyum asetat) added, or continued on Ammonium acetate(Amonyum asetat) until sacrifice. The NOAEL for developmental toxicity was 4293 mg/kg bw/day . Read-across from the analogue Sodium Acetate, based on molecular weights: Pregnant CD-1 mice were treated by oral gavage with Sodium Acetate on days 8-12 of gestation. For Ammonium acetate(Amonyum asetat), theNOAEL is calculated to be939.66 mg/kg bw/day (based on maternal toxicity: mortality, pregnancy and resorption; and on neonatal effects: mortality and body weight). Read-across from the analogue Citric Acid, based on molecular weights: A study on rats and mice daily treated by feed before, during, and after mating. For Ammonium acetate(Amonyum asetat), the NOAEL is calculated to be equal or greater than 3009.37 mg/kg bw/day (basis for effect: number of pregnancies, number of young born, or survival of young). Read-across from the analogue substance Calcium Formate, based on molecular weights: A three-generation drinking water study was performed. For Ammonium acetate(Amonyum asetat), the NOAEL is calculated to be equal or higher than 236.96 mg/kg bw/day. Read-across from Acetic Acid, based on molecular weights: A one-generation study was performed on female mice, rats and rabbits with Acetic Acid. The read-across approach was applied and the NOAEL with the substance Ammonium acetate(Amonyum asetat) acetate is calculated to be equal or greater than 2055.47 mg/kg bw/day for maternal and developmental toxicity in mice, rats, and rabbits. Applicant's summary and conclusion Interpretation of results: not classified Remarks: Migrated information Criteria used for interpretation of results: EU Conclusions: The (4h) LD 50 for substance Ammonium acetate(Amonyum asetat) is calculated to be gr
AMMONIUM ACETATE
Ammonium Acetate is a biodegradable de-icing agent.
Ammonium Acetate is a white crystalline solid formed when ammonia reacts with acetic acid.
Ammonium acetate is an ammonium salt obtained by the reaction of ammonia with acetic acid.


CAS Number: 631-61-8
EC Number: 211-162-9
Linear Formula: CH3CO2NH4
Chemical formula: C2H7NO2


Ammonium acetate, also known as spirit of Mindererus in aqueous solution, is a chemical compound with the formula NH4CH3CO2.
Ammonium Acetate is a white, hygroscopic solid and can be derived from the reaction of ammonia and acetic acid.
Ammonium Acetate is available commercially.


Ammonium Acetate has a relatively low melting point (114°C) for a salt.
Ammonium Acetate acts as a food acidity regulator and buffer.
Ammonium acetate has a number of distinctive properties.


Ammonium acetate or C2H7NO2 appears in the form of a crystalline white solid with a slight acetous odour.
This ammonium salt is derived from the reaction of ammonia and acetic acid.
The chemical name of this salt is Ammonium Acetate while it is even known as the spirit of Mindererus on the aqueous form.


The other names of Ammonium Acetate include ammonium ethanoate and Azanium Acetate.
Ammonium Acetate is extensively used in the preservation of foods; in pharmaceuticals and the chemical analysis procedure.
Ammonium Acetate salt works most effectively when used in the form of a food acidity regulator.


Ammonium Acetate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Ammonium Acetate is a biodegradable de-icing agent.


Ammonium Acetate is a white crystalline solid formed when ammonia reacts with acetic acid.
Ammonium acetate is an ammonium salt obtained by the reaction of ammonia with acetic acid.
Ammonium acetate is a chemical compound with the formula NH4CH3CO2.


Ammonium Acetate is a white, hygroscopic solid and can be derived from the reaction of ammonia and acetic acid.
Ammonium Acetate is available commercially.
Ammonium Acetate has a variety of applications in molecular biology and chromatography.


Ammonium Acetate is a useful reagent for the purification and precipitation of DNA and protein.
Ammonium Acetate Solution is a clear, near colourless liquid manufactured by reacting ammonia solution with glacial acetic acid to produce strengths ranging from 50% to 66%.


Ammonium Acetate is typically supplied in bulk tankers, 200 litre drums or 1000 litre IBC’s for use in a wide range of applications including metals processing, latex manufacture, chemical intermediate manufcature and pH control.
Ammonium Acetate is used as a raw material in the synthesis of pesticides, herbicides, and non-steroidal anti-inflammatory drugs.
Moreover, Ammonium Acetate is the precursor in the acetamide synthesis (a chemical compound that we use to produce plasticizers):
CH3COONH4→ CH3C(O)NH2+ H2O


In industries, they use Ammonium Acetate to acidify textiles and hair and some countries use it as a food acidity regulator.
With acetic acid, Ammonium Acetate is a buffering agent. In organic chemistry, ammonium acetate found its use as a catalyst, in reactions such as Knoevenagel condensations.


We can use Ammonium Acetate as a fertilizer and in the synthesis of explosives.
Ammonium Acetate is volatile at low pressure and because of this, industries and scientists have used it to replace cell buffers with non-volatile salts in preparing samples for mass spectrometry.


Besides, Ammonium Acetate is popular as a buffer for mobile phases for HPLC and ELSD detection for this reason.
Moreover, other salts that they have used for this include ammonium formate.
The Hydrogen atom in Acetic acid was replaced by an Ammonium ion.


Most commonly Ammonium Acetate is used as a food acidity regulator, is also used in dialysis processes, and is used as a reagent in agricultural products and it is not harmful with less exposure.
Ammonium Acetate consists of Carbon, Nitrogen, Hydrogen, and Oxygen atoms.


One carbon atom is linked to 3 Hydrogen atoms and another carbon atom that linked to 2 oxygen atoms, one with a double bond and one with a single bond.
Single bond linked oxygen atom again linked to Nitrogen have 4 hydrogen atoms.
Ammonium acetate is also called as Spirit of mindererus.


Ammonium Acetate is a chemical compound that appears in the form of a white crystalline solid with a slight acetous odor.
Ammonium Acetate contains 2 carbons, 7 hydrogens, 1 Nitrogen, and 2 Oxygen atoms.
The Hydrogen atom in the Acetic acid was replaced by an Ammonium ion.
Finally, it gives Ammonium acetate.


And it is a precursor of Acetamide which is used as a diuretic.
On further heating, it will be converted into Acetonitrile (Methyl cyanide).
Ammonium acetate (NH4OAc) is a salt formed from the reaction of ammonia and acetic acid.
Ammonium Acetate can be useful for applications that require buffered solutions.



USES and APPLICATIONS of AMMONIUM ACETATE:
Use to the environment of Ammonium Acetate can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid and in the production of articles.


Release to the environment of Ammonium Acetate can occur from industrial use: manufacturing of the substance, formulation of mixtures, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.


Other release to the environment of Ammonium Acetate is likely to occur from: indoor use as processing aid, outdoor use as processing aid, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).


Ammonium Acetate can be used to precipitate DNA from enzymatic reactions.
Ammonium acetate is widely used in perfumes, fragrances, cosmetics and personal care products.
Ammonium Acetate has use in healthcare, scientific research and development, agriculture, forestry, fisheries, construction and civil works, formulation of mixtures and/or repackaging.


Ammonium Acetate is used in the formulation and repackaging of laboratory chemicals, leather processing products, metal surface treatment products, non-metal surface treatment products, pH regulators and water treatment products, polymers.
Ammonium Acetate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Other releases of Ammonium Acetate into the environment are likely to occur from: indoor use as a processing aid, outdoor use as a processing aid, indoor use in long-life materials with a low release rate (eg flooring, furniture, toys, building materials, curtains, shoes, leather goods, paper and cardboard products, electronic equipment) and indoor use in long-lasting materials with a high emission rate (eg separation from fabrics, textiles during washing, removal of interior paints).


Release to the environment of Ammonium Acetate can occur from industrial use: manufacturing of the substance, formulation of mixtures, formulation in materials, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.


Other release to the environment of Ammonium Acetate is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints), indoor use as processing aid and outdoor use as processing aid.


Ammonium Acetate can be found in complex articles, with no release intended: vehicles, machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and electrical batteries and accumulators.
Ammonium Acetate can be found in products with material based on: fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), metal (e.g. cutlery, pots, toys, jewellery) and rubber (e.g. tyres, shoes, toys).


Ammonium Acetate is used in the following products: pH regulators and water treatment products, laboratory chemicals and fertilisers.
Ammonium Acetate is used in the following areas: health services, scientific research and development, agriculture, forestry and fishing and building & construction work.


Ammonium Acetate is used for the manufacture of: food products and textile, leather or fur.
Release to the environment of Ammonium Acetate can occur from industrial use: formulation of mixtures and formulation in materials.
Ammonium Acetate is used in the following products: perfumes and fragrances and cosmetics and personal care products.


Other release to the environment of Ammonium Acetate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use as processing aid, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).


Other release to the environment of this substance is likely to occur from: indoor use as processing aid.
Ammonium Acetate is often used with acetic acid to create a buffer solution.
Ammonium Acetate acts as a catalyst in the Knoevenagel condensation.


Ammonium acetate is also used as a food additive as an acidity regulator.
Ammonium Acetate is widely used in perfumes, fragrances, cosmetics and personal care products.
Ammonium Acetate has use in healthcare, scientific research and development, agriculture, forestry, fisheries, construction and civil works, formulation of mixtures and/or repackaging.


Other releases of Ammonium Acetate into the environment are likely to occur from: indoor use as a processing aid, outdoor use as a processing aid, indoor use in long-life materials with a low release rate (eg flooring, furniture, toys, building materials, curtains, shoes, leather goods, paper and cardboard products, electronic equipment) and indoor use in long-lasting materials with a high emission rate (eg separation from fabrics, textiles during washing, removal of interior paints).


Ammonium Acetate is used in the formulation and repackaging of laboratory chemicals, leather processing products, metal surface treatment products, non-metal surface treatment products, pH regulators and water treatment products, polymers.
Ammonium Acetate is widely used in the chemical analysis, in the pharmaceutical industry, the food sector in preserving foods, and in various other industries too.


Ammonium Acetate is also used as a buffer in topical personal care and cosmetic products in manufacturing skin lotions, shampoos, conditioners and more.
Ammonium Acetate is used as a catalyst in the Knoevenagel condensation and as a source of ammonia in the Borch reaction in organic synthesis.
Ammonium Acetate is used as a protein precipitating reagent in dialysis to remove contaminants via diffusion.


Ammonium Acetate is used as a reagent in agricultural chemistry for determination of soil CEC (cation exchange capacity) and the determination of available potassium in soil wherein the ammonium ion acts as a replacement cation for potassium.
Ammonium acetate is also used as a food additive as an acidity regulator.


Ammonium Acetate is the main precursor to acetamide:
NH4CH3CO2 → CH3C(O)NH2 + H2O
Ammonium Acetate is also used as a diuretic.


There are large scale uses of Ammonium acetate.
Ammonium Acetate is used in the form of a food acidity regulator.
Ammonium Acetate is the food additive used for changing or controlling the alkalinity or acidity of foods.


Ammonium Acetate is also widely used in the form of a catalyst in the Knoevenagel condensation procedure.
Ammonium Acetate serves as one of the best sources of ammonia is the Borch reaction during organic synthesis.
Ammonium acetate is used in combination with wholly distilled water for making a kind of protein precipitating reagent.


Ammonium Acetate even serves in the form of a buffer for ESI or electrospray ionization mass spectrometry of molecules and proteins and the form of a mobile phase for HPLC or high-performance liquid chromatography.
Quite rarely though, ammonium acetate is even used in the form of a biodegradable de-icing agent.


Ammonium Acetate even works best when used as a diuretic.
Ammonium acetate tends to be unstable at low pressure, and this is why it is used for substituting cell buffers with different non-explosive salts in the preparation of mass spectrometry samples.


Ammonium Acetate is used in the manufacture of explosives.
Ammonium Acetate is used for making foam rubber.
Ammonium Acetate is used for preserving meat.


Ammonium Acetate is used for manufacturing vinyl plastics.
Ammonium Acetate is used in different agricultural products.
In analytical chemistry, Ammonium Acetate is used in the form of a reagent.


Ammonium Acetate is used as a reagent in different dialysis procedures for the elimination of contaminants through diffusion.
In agricultural chemistry, Ammonium Acetate, when used as a reagent, helps in determining soil CEC or cation exchange capacity along with the availability of potassium in the soil.


Ammonium Acetate is used as food acidity regulator.
Ammonium Acetate is used in agricultural products.
Ammonium Acetate is used as a reagent in dialysis processes to eliminate the contaminants.


Ammonium Acetate is used for preservation of food items.
Ammonium Acetate is used as a reagent in determining soil cation exchange capacity.
Ammonium Acetate is used in the making of foam rubber process.


Ammonium Acetate is used as a catalyst in the Knoevenagel condensation procedure.
Ammonium Acetate is used to prepare buffer solutions.
Ammonium Acetate is used in manufacturing of vinyl plastics.


Ammonium Acetate can be used in the HPLC and MS analysis of peptides, oligosaccharides, and proteins.
Ammonium acetate is a salt that can be used as a buffer.
Ammonium acetate is commonly used as an additive for regulating the acidity of various foodstuffs and as a catalyst for Henry reactions.


Ammonium Acetate is also used in agriculture, where it functions as a fungicide and insecticide.
In biochemical research, ammonium acetate is used for precipitation of DNA and RNA.
Ammonium Acetate is especially useful for precipitating RNA from dilute solutions and has been shown to produce less detergent precipitation than sodium chloride salt.


Likewise, ammonium acetate can be used to facilitate precipitation in the extraction of proteins, particularly from tissues not naturally rich in them.
Ammonium Acetate is a chemical compound that contains a weak acid and weak base, so it can be used as a buffering agent along with Acetic acid.
One reaction in which ammonium acetate is commonly used in is Henry reactions.
Ammonium acetate is mainly used as a non-lethal attractant for the Mediterranean fruit fly.


However, Ammonium Acetate also has fungicidal and insecticidal properties.
Ammonium Acetate is non-volatile, highly soluble in water.
Ammonium Acetate is a reagent used in chromatographic analysis of various compounds, such as oligos, proteins, and peptides.



STRUCTURAL FORMULA OF AMMONIUM ACETATE:
As Ammonium Acetate salt is constituted of a weak acid and a weak base and is often used with acetic acid to create a buffer solution.
Ammonium acetate chemical component is volatile at low pressures because it has been used to replace cell buffers with non-volatile salts in preparing the chemical samples.
Ammonium acetate is an ammonium salt obtained by the reaction of ammonia with acetic acid.
Ammonium Acetate has a relatively low melting point (114°C) for a salt.
Ammonium Acetate acts as a food acidity regulator and buffer.



PRODUCTION OF AMMONIUM ACETATE:
Ammonium acetate is produced by the neutralization of acetic acid with ammonium carbonate or by saturating glacial acetic acid with ammonia.
Obtaining crystalline ammonium acetate is difficult on account of its hygroscopic nature.



AMMONIUM ACETATE PRODUCTION:
Two methods can be used for obtaining Azanium acetate, and they are:
Through the saturation of glacial acetic acid or CH3COOH with NH3 or ammonia.
Through the neutralization of acetic acid with (NH4)2CO3 or ammonium carbonate.
These are the two basic methods used for obtaining ammonium acetate, though some new methods have also surfaced in recent years.
Ammonium acetate functions in the form of an acetamide precursor. This results in a reaction that follows like this:
NH4CH3CO2 → CH3C (O) NH2 + H2O



UNDERSTANDING AMMONIUM ACETATE SOLUBILITY
Coming to ammonium acetate solubility, it is water-soluble.
The solubility of this acetous salt, Ammonium Acetate, in water corresponds to around 102 g/100 mL at zero degrees temperature.
The water solubility of Ammonium Acetate in water increases with an increase in temperature.
Take for instance; iAmmonium Acetate's solubility will reach 5330 grams per litre of water at a temperature of 80 °C.
It is worth noting that Ammonium Acetate even has liquid ammonia, acetone and alcohol solubility.
Ammonium Acetate is thinly soluble in methanol with the solubility corresponding to 7.89 g/100 mL at 15°C and 131.24 g/100 g at 94.2°C.
Other solubility specifications of Ammonium Acetate include:
Water solubility
148 g/100 mL at 4°C
143 g/100 mL at 20°C
533 g/100 mL at 80°C
Dimethylformamide solubility
0.1 g/100 g



AMMONIUM ACETATE PROPERTIES:
This deliquescent acetate salt comes with a low melting point of 114°C.
Ammonium Acetate density: 1.17 g/cm3
Molecular weight: 277.083 g/mol
Ammonium acetate viscosity: 21
Molecular formula: C2H7NO2
Monoisotopic mass: 77.047676 Da
Ammonium acetate structure: C2H7NO2



AMMONIUM ACETATE FORMULA
The chemical formula for ammonium acetate C2H7NO2.
Other names are the spirit of Mindererus, Ammonium ethanoate, Azanium acetate



STRUCTURE OF AMMONIUM ACETATE:
Ammonium acetate contains 2 Carbon atoms, 7 Hydrogen atoms, 1 Nitrogen atom, and 2 Oxygen atoms.
The chemical formula of Ammonium acetate is C2H7NO2.
In the acetic acid one Hydrogen atom was replaced by an ammonium ion.
The IUPAC name of Ammonium Acetate is Ammonium Ethanoate.



PHYSICAL PROPERTIES OF AMMONIUM ACETATE:
Ammonium acetate is a crystalline white solid (deliquescent) with a slight acetous odor.
The density of Ammonium acetate is 1.17 g.cm3 at 20°C.
The Melting point of Ammonium acetate is 113°C (or) 235°F.

The solubility of Ammonium acetate in water is 102g/100ml at 0°C.
The Molar mass of Ammonium acetate is 77.083 g/mol.
Chemical properties of Ammonium Acetate

Ammonium acetate is a precursor of acetamide and it is used as a diuretic.
On further heating, the Acetamide will convert into Acetonitrile (Methyl Cyanide).
Commonly Ammonium acetate is used only in the preparation or synthesis of Acetamide.
NH4CH3CO2 ⇢ CH3C(O)NH2 + H2O



PREPARATION OF AMMONIUM ACETATE:
Ammonium acetate is prepared by reacting Glacial Acetic acid with Ammonia.
CH3COOH + NH3 ⇢ CH3COONH4
Ammonium acetate is prepared by neutralizing Acetic acid with Ammonium Carbonate.
2CH3COOH + [NH4]2CO3 ⇢ 2CH3COONH4 + H2CO3
H2CO3 ⇢ CO2 + H2O



BUFFER:
As the salt of a weak acid and a weak base, ammonium acetate is often used with acetic acid to create a buffer solution.
Ammonium acetate is volatile at low pressures.
Because of this, Ammonium Acetate has been used to replace cell buffers that contain non-volatile salts in preparing samples for mass spectrometry.
Ammonium Acetate is also popular as a buffer for mobile phases for HPLC with ELSD detection for this reason.
Other volatile salts that have been used for this include ammonium formate.

When dissolving ammonium acetate in pure water, the resulting solution typically has a pH of 7, because the equal amounts of acetate and ammonium neutralize each other.
However, ammonium acetate is a dual component buffer system, which buffers around pH 4.75 ± 1 (acetate) and pH 9.25 ± 1 (ammonium), but it has no significant buffer capacity at pH 7, contrary to common misconception.



HISTORY OF AMMONIUM ACETATE:
The synonym Spirit of Mindererus is named after R. Minderer, a physician from Augsburg.



PHYSICAL PROPERTIES OF AMMONIUM ACETATE:
Ammonium Acetate is a hygroscopic white solid with a slightly acidic odor.
Furthermore, Ammonium Acetate's melting point is 113oC.
Also, Ammonium Acetate is highly soluble in water and its density in this liquid is 1.17 g/mL-1.



CHEMICAL PROPERTIES OF AMMONIUM ACETATE
Ammonium Acetate is a slat of a weak acid (acetic acid) and a weak base (ammonia).
We use Ammonium Acetate with acetic acid to prepare a buffer solution to regulate its pH.
Nevertheless, Ammonium Acetate's use as a buffering agent is not very extensive because ammonium acetate can be volatile in low pressures.



FORMULA OF AMMONIUM ACETATE:
Ammonium Acetate is a salt that has interesting chemical properties and due to this reason, the pharmaceutical industry uses it as an intermediary and raw material in various processes.
Ammonium Acetate is a salt that forms from the reaction of ammonia and acetic acid.
Also, Ammonium Acetate is useful for applications that require buffer solutions.
The Henry reactions are the most common reactions that use ammonium acetate.
In an aqueous solution, Ammonium Acetate is a chemical compound that we know by the name spirit of Mindererus or ammonium acetate, which is a white, hygroscopic solid we can derive from the reaction of ammonia and acetic acid.



AMMONIUM ACETATE FORMULA AND STRUCTURE:
Ammonium Acetate's chemical formula is NH4CH2CO2 or CH2COONH4.
The molecular formula of ammonium acetate is C2H7NO2and its molar mass is 77.08 g/mol-1.
Also, Ammonium Acetate is a slat of acetate ion COO-1(from acetic acid dissociation in water) and ammonium ion NH4+(from ammonia dissociation in water).

Ammonium acetate is volatile at low pressure because it has been used to replace cell buffers with non-volatile salts that help in the preparation of chemical samples.
Ammonium Acetate's common representation of organic molecule’s chemical structure can be written as below:



AMMONIUM ACETATE OCCURRENCE:
In nature, ammonium acetate is not present in a free compound state.
But, ammonium and acetate ions are present in many biochemical processes.



PREPARATION OF AMMONIUM ACETATE:
Just like other acetates, we can also synthesize ammonium acetate in a similar way to other acetates that is through neutralization of acetic acid.
Furthermore, this synthesis uses acetic acid that we neutralize by adding ammonium carbonate.
Besides, in the chemical industries, this method uses glacial acetic acid that is saturated with ammonia:

2CH3COOH + (NH4)2CO3→ 2CH3COONH4+ H2CO3
H2CO3→ CO2+ H2O
CH3COOH + NH3→ CH3COONH4



PHYSICAL and CHEMICAL PROPERTIES of AMMONIUM ACETATE:
CAS Number: 631-61-8
Molecular Weight: 77.08
EC Number: 211-162-9
Chemical formula: NH4CH3CO2
Molecular weight: 77.083 g/mol
Density: 1.17 g/cm3 (20 °C), 1.073 g/cm3 (25 °C)
Melting Point: 114°C
Color: White
pH: 7.0
Physical Form: Solid
Assay Percent Range: ≥97 %
Linear Formula: CH3COONH4
Merck Index: 15, 492
Formula Weight: 77.08
Percent Purity: ≥97%
Chemical Name or Material: Ammonium Acetate
Melting point: 113 °C (235 °F; 386 K)

Chemical formula: C2H7NO2
Molar mass: 77.083 g·mol−1
Appearance: White solid crystals, deliquescent
Odor: Slightly acetic acid like
Density: 1.17 g/cm3 (20 °C), 1.073 g/cm3 (25 °C)
Melting point: 113 °C (235 °F; 386 K)
Solubility in water: 102 g/100 mL (0 °C)
148 g/100 mL (4 °C)
143 g/100 mL (20 °C)
533 g/100 mL (80 °C)
Solubility: Soluble in alcohol, SO2, acetone, liquid ammonia
Solubility in methanol: 7.89 g/100 mL (15 °C), 131.24 g/100 g (94.2 °C)
Solubility in dimethylformamide: 0.1 g/100 g
Acidity (pKa): 9.9
Basicity (pKb): 33

Magnetic susceptibility (χ): -41.1·10−6 cm3/mol
Viscosity: 21
Structure: Crystal structure: Orthorhombic
Thermochemistry
Std enthalpy of formation (ΔfH⦵298): −615 kJ/mol
Molecular Weight: 77.08
Molecular Formula: C2H7NO2
Boiling Point: 117.1ºC at 760 mmHg
Melting Point: 110-112ºC
Flash Point: 136ºC
Purity: min 96.50 %
Density: 1.07
Appearance: White adhering crystals
Storage: 2-8ºC
Hazard Codes: T
HS Code: 2915299090
Log P: 0.41480
PSA: 4.54

RIDADR: UN 9079
RTECS: AF3675000
Safety Statements: S24/25
Stability: Stable at room temperature in closed containers under normal storage and handling conditions.
Deliquescent; tends to lose ammonia.
Appearance: White crystalline hygroscopic powder
Assay: ≥ 97.0 %
Chloride (Cl): ≤ 0.0005 %
Heavy Metals (as Pb): ≤ 0.0005 %
Insoluble Matter: ≤ 0.005 %
Iron (Fe): ≤ 0.0005 %
Nitrate: ≤ 0.001 %
pH, 5% solution in H2O @25 ºC: 6.7 - 7.3
Residue after Ignition: ≤ 0.01 %
Sulfate: ≤ 0.001 %

Physical state: solid
Color: white
Odor: weakly of acetic acid
Melting point/freezing point:
Melting point/range: 110 - 112 °C - dec.
Initial boiling point and boiling range: Decomposes below the boiling point.
Flammability (solid, gas): No data available
Upper/lower flammability or
explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water
log Pow: -2,79 - (Lit.), Bioaccumulation is not expected.
Vapor pressure: < 0,001 hPa
Density: 1,17 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available

CAS number: 631-61-8
EC number: 211-162-9
Grade: ACS,Reag. Ph Eur
Hill Formula: C₂H₇NO₂
Chemical formula: CH₃COONH₄
Molar Mass: 77.08 g/mol
HS Code: 2915 29 00
Density: 1.17 g/cm3 (20 °C)
Melting Point: 114 °C
pH value: 6.7 - 7.3 (50 g/l, H₂O, 25 °C)
Vapor pressure: Bulk density: 410 kg/m3
Solubility: 1480 g/l



FIRST AID MEASURES of AMMONIUM ACETATE:
-Description of first-aid measures
*If inhaled
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed
No data available



ACCIDENTAL RELEASE MEASURES of AMMONIUM ACETATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of AMMONIUM ACETATE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of AMMONIUM ACETATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of AMMONIUM ACETATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Hygroscopic.



STABILITY and REACTIVITY of AMMONIUM ACETATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



AMMONIUM BICARBONATE
CAS No: 1066.33.7
Formula: CH5NO3 / NH4HCO3
Molecular mass: 79.1



APPLICATIONS


Ammonium bicarbonate is commonly used as an inexpensive Ammonium bicarbonaterogen fertilizer in China, but is now being phased out in favor of urea for quality and stabil Ammonium bicarbonatey.
Ammonium bicarbonate is used as a component in the production of fire, extinguishing compounds, pharmaceuticals, dyes, pigments,and Ammonium bicarbonate is also a basic fertilizer, being a source of ammonia.
Ammonium bicarbonate is still widely used in the plastics and rubber industry, in the manufacture of ceramics, in chromeleather tanning, and for the synthesis of catalysts.

Ammonium bicarbonate is also used for buffering solutions to make them slightly alkaline during chemical purification, suchas high.performance liquid chromatography.
Because Ammonium bicarbonate entirely decomposes to volatile compounds, this allows rapid recovery of the compound of interest by freeze drying.
Ammonium bicarbonate is also a key component of the expectorant cough syrup "Senega and Ammonia".

Ammonium bicarbonate is listed in Old World baking recipes.
Especially, in Scandinavian gingerbread, Polish ammonia cookies and tranditional German Spekulatius Christmas cookies.
Ammonium bicarbonate is an inorganic salt commonly used in the food industry.

Ammonium bicarbonate can be generated by the interaction of gaseous carbon dioxide and aqueous ammonia.
The add Ammonium bicarbonateion of ammonium bicarbonate to microbial fuel cells (MFCs) has been reported to improve Ammonium bicarbonate's functioning by altering the porosity and pore distribution of catalyst layers.
A recent study reports the use of bubble column evaporator (BCE) based analysis of Ammonium bicarbonates thermal degradation in aqueous solution.


Some applications of Ammonium bicarbonate:

Food Industry
Fertilizer
Pharmaceuticals
Plastic and Rubber
Ceramics
Other Industries


Ammonium bicarbonate is used in, for example, Swedish "drömmar" biscuites and Danish "brunkager" Christmas biscuites, and GermanLebkuchen.
In many cases Ammonium bicarbonate may be replaced with baking soda or baking powder, or a combination of both,depending on the recipe compos Ammonium bicarbonateion and leavening requirements.

Compared to baking soda or potash, hartshorn has the advantage of producing more gas for the same amount of agent, and of not leaving any salty or soapy taste in the finished product, as Ammonium bicarbonate completely decomposes into waterand gaseous products that evaporate during baking.
Ammonium bicarbonate cannot be used for moist, bulky baked goods however, such as normal bread or cakes, since some ammonia will be trapped inside and will cause an unpleasant taste.
Ammonium bicarbonate has been assigned E number E503 for use as a food additive in the European Union

Moreover, Ammonium bicarbonate can be used as medicine and reagents: Alkali; leavening agent; buffer; aerating agent.
Ammonium bicarbonates combination with sodium bicarbonate can be used as the raw materials of leavening agent such as bread, biscuites and pancakes.

Baking powder also takes Ammonium bicarbonate as the main ingredient, together with the acidic substances.
Ammonium bicarbonate can also be used as raw material of foam powder juice.

The dosage of the blanching of green vegetables and bamboo shoots should be 0.1% to 0.3%.
Ammonium bicarbonate can be used as analytical reagent; used for ammonium salt synthesis: Pharmaceuticals; baking powder; dyeing.

Ammonium bicarbonate can be used for fabric degreasing.
Ammonium bicarbonate can also be used as foamed plastics.

Ammonium bicarbonate can be used for buffer applications such as lyophilization and matrix assisted laser desorption.
Ammonium Bicarbonate is a dough strengthener, a leavening agent, a ph control agent, and a texturizer. prepared by reacting gaseous carbon dioxide with aqueous ammonia.

Crystals of ammonium bicarbonate are precipitated from solution and subsequently washed and dried.
Also known as hartshorn and rock ammonia, ammonium bicarbonate is soluble in water but decomposes when heated.
Ammonium bicarbonate was used in place of ammonia.

Ammonium bicarbonate is used in the food industry as a leavening agent for flat baked goods, such as cookies and crackers.
Ammonium bicarbonate was commonly used in the home before modern day baking powder was made available.

Many baking cookbooks, especially from Scandinavian countries, may still refer to Ammonium bicarbonate as hartshorn or hornsalt, while Ammonium bicarbonate is known as "hirvensarvisuola" in Finnish, "hjortetakksalt" in Norwegian,"hjortetakssalt" in Danish, "hjorthornssalt" in Swedish, and "Hirschhornsalz" in German.
Although there is a slight smell of ammonia during baking, this quickly dissipates, leaving no taste.

However, Ammonium bicarbonate contains low nitrogen content and is also easy to caking.

Ammonium bicarbonate can be used as analytical reagent as well as being used in synthesizing ammonium salt and fabric degreasing.
Ammonium bicarbonate can promote crop growth and photosynthesis; trigger seedlings and the growth of leaves.
Ammonium bicarbonate can be used as top dressing as well as being directly applied as ground fertilizer as food leavening agent and bulking agent.

Ammonium bicarbonate can be used as a senior food fermentation agent.
Ammonium bicarbonates combination with sodium bicarbonate can be used as the raw materials of leavening agent such as bread, biscuites and pancakes.
Ammonium bicarbonate can also be used as raw material of foam powder juice, as well as being used for the blanching of green vegetables and bamboo shoots.

The powdered baking ammonia cannot be used for bulky baked foods; however, Ammonium bicarbonates applications are not only bounded to the food industry.
Ammonium bicarbonates use can found in the agricultural, pharmaceutical, textile, and ceramic industries, among others.
Ammonium bicarbonate has bestowed the new entrants and emerging players with lucrative opportunities and untapped new avenues for them.

Advantages of using Ammonium bicarbonate in baked goods include:

The absence of alkaline taste residue often encountered with sodium bicarbonate
Ammonium bicarbonate doesn’t affect the pH of the baked goods.
In high moisture baked goods (in excess of 5%), ammonium bicarbonate may lead to the development of ammoniacal flavor.

This is why Ammonium bicarbonate’s most suited for low moisture products such as biscuites, crackers, cookies, and waffle cones.
Typically, Ammonium bicarbonate is mixed in with the liquid ingredients to ensure Ammonium bicarbonates dissolution prior to incorporating into the dry mix.
In some formulas, Ammonium bicarbonate is used in combination with 30.50% baking soda.


Ammonium bicarbonate is a common leavening agent used in the baking industry and has been reported to be used in Guangdong-style steamed breads.
Ammonium bicarbonate releases carbon dioxide and ammonia gas when the dough temperature reaches 40°C.
If Ammonium bicarbonate is used at the correct addition rate, Ammonium bicarbonate significantly improves steamed bread color and volume.

In addition, Ammonium bicarbonate can function as a buffering agent.
Overuse of ammonium bicarbonate can result in ammoniacal taints in the final steamed bread.
Ammonium bicarbonate is more commonly used in low moisture products such as English-style biscuites.

Ammonium bicarbonate is produced by combining carbon dioxide and ammonia:
CO2 + NH3 + H2O → (NH4)HCO3

Since ammonium bicarbonate is thermally unstable, the reaction solution is kept cold, which allows the precipitation of the product as white solid.
About 100,000 tons of Ammonium bicarbonate were produced in this way in 1997.

Ammonia gas passed into a strong aqueous solution of the sesquicarbonate (a 2:1:1 mixture of (NH4)HCO3, (NH4)2CO3, andH2O) converts Ammonium bicarbonate into normal ammonium carbonate ((NH4)2CO3), which can be obtained in the crystalline condition from a solution prepared at about 30 °C.
This compound on exposure to air gives off ammonia and reverts to ammonium bicarbonate.


Ammonium bicarbonate (Ammonium bicarbonate) was used in the following studies:

To derivatize histone proteins from human monocyte derived macrophages (MDM) by propionylation.
Destaining of silver-stained proteins in polyacrylamide gel bands during the peptide mass profiling using a mass spectrometer.
Digestion of proteins isolated from Xenopus egg extracts in coomassie blue-stained gel bands during the analysis of microtubule binding proteins.


Ammonium bicarbonate is one of nitrogen fertilizer industrial products, being the major varieties of small nitrogenous fertilizer plants in China, being one of the purification products of coke oven in the coking plant.
Coking plant takes concentrated ammonia as raw materials for reaction with carbon dioxide to generate ammonium bicarbonate crystals with centrifugal filtering to obtain ammonium bicarbonate products.
Ammonium bicarbonate is easy to be subject to decomposition.

Ammonium bicarbonate is appropriate to be packed with the combination of inner plastic film and external plastic bag or 3-layers of kraft paper sacks, both need to be sealed and stored in a warehouse of being cool, low-temperature, dry and ventilated to prevent moisture, rain and sun.
Ammonium bicarbonate is used as nitrogen fertilizer, being applicable to a variety of soils, can simultaneously provide the ammonium nitrogen and carbon dioxide demanded by crop growth.


Uses of Ammonium bicarbonate:

Pharma
Lubricants
Water Treatment
Cleaning
Animal NutrAmmonium bicarbonateion
Coatings & Construction
Food and NutrAmmonium bicarbonateion
Agriculture
Cosmetics
Polymers


Ammonium bicarbonate is used in the food industry as a food additive.
Ammonium bicarbonate is used in fire extinguishers.
Ammonium bicarbonate is used in the manufacturing of dyes.

Ammonium bicarbonate is used as a fertilizer.
Ammonium bicarbonate is used to produce ammonium salt.
Ammonium bicarbonate is used in the manufacturing of pharmaceutical products.

Ammonium bicarbonate is used in the making of paints.
Ammonium bicarbonate is used in the manufacturing of ceramics.

Ammonium bicarbonate is used in leather tanning.
Ammonium bicarbonate is used in cooling baths.


Production of Ammonium bicarbonate:

Ammonium hydrogen carbonate is obtained by combining carbon dioxide (CO2) and ammonia (NH3):
Ammonium bicarbonateh the substance known as baking powder or baking soda.
However, the use of actual Ammonium Bicarbonate substance is still preferred by some who want a lighter or crispier texture than can be achieved by using baking powder or soda.

Ammonium bicarbonate can be used as basic fertilizer for topdressing, but not suitable to be used as seed manure.
When being used for topdressing, we should prevent the drop of ammonium bicarbonate onto the plant, to avoid ammonia hazards.
The shortcoming of ammonium bicarbonate as a fertilizer lies in Ammonium bicarbonates chemical instability.

After the addition of crystalline modifier, the crystal of ammonium bicarbonate is enlarged and the water content is reduced, reducing the phenomenon of easily subjecting to decomposition and agglomeration.
Ammonium bicarbonate is an inorganic chemical compound which is usually used as a raising or leavening agent in the food industry.
Ammonium bicarbonate is utilized as a source of carbon in low-moisture baked foods.

Ammonium bicarbonate is generally produced by coursing the carbon dioxide through a stream of aqua ammonia.
The result of the reaction is unstable and thus Ammonium bicarbonate is kept in a cold atmosphere.


Common applications of Ammonium Bicarbonate:

Cookies
Crackers
Pastas
Frozen dairy products
Bakery ingredients
Pigments and paints
Agriculture
Fire extinguishers

A leavening agent is a substance that releases gas in baked goods to impart a light texture.
A white powder made for use as a leavening agent which is added as an ingredient when preparing many different types of baked goods that will have thin shells or crusts such as puff pasteries, flat breads, crackers, and some cookies.
Ammonium Biocarbonate is typically used with smaller baked goods that can quickly disperse and evaporate the ammonia gas as Ammonium bicarbonate builds up within the baked Ammonium bicarbonateem.

During the baking process, an ammonia aroma may be present, but Ammonium bicarbonate will not remain and will not benoticed in the baked goods when they are eaten.
The result of using Ammonium Bicarbonate is a baked good that will have an light, airy, crispy, and somewhat fluffy texture.
The term Ammonium Bicarbonate is actually an old term that is now more commonly referred to and replaced in recipes.

Ammonium bicarbonate, NH4HCO3, is a common leavening agent which releases CO2 without the need for an acid.
Unlike baking powder or soda, Ammonium bicarbonate does not leave an alkaline taste, characteristic of soda or baking powder.

This ingredient is not used in high volume cakes, but mostly in:
Extra crisp cookies
Cream.puff pastries
Crackers


Advantages of Ammonium Carbonate in Baking:

Ammonium carbonate lends a distinctive crispness and lightness to the baked good, which why Ammonium bicarbonate is still listed in certain recipes, despite the overwhelming use of baking powder and baking soda in modern baked goods.
You can substitute baking powder for ammonium carbonate in a pinch, but the final baked product may not have the same texture.
The designs on molded cookies are also said to keep their shape much better when ammonium carbonate is used.

Usually, ammonium carbonate is mixed in with the liquid before adding to the dry ingredients, so that Ammonium bicarbonate dissolves well and mixes thoroughly.
Ammonium bicarbonate must be stored dry, in a well.sealed container, because Ammonium bicarbonate absorbs moisture easily and clumps.
To tell if Ammonium bicarbonate is still active, place a small amount in hot water.

If Ammonium bicarbonate bubbles vigorously, you can use Ammonium bicarbonate in your recipes.
Ammonium carbonate is used for leavening in cookies, flat biscuites, or crackers.
In German baking, Ammonium bicarbonate's known as hirschhornsalz or hartshorn, and Ammonium bicarbonate is also called baker's ammonia.

Ammonium bicarbonate is not used for cakes since the gaseous ammonia given off during baking cannot escape the thicker, higher batters and would make the baked goods smell bad.
Ammonium bicarbonate leaves no salty or soapy taste residue as baking powder sometimes does since Ammoniumbi carbonate completely decomposes into ammonia and carbon dioxide.

Ammonium bicarbonate (NH₄HCO₃) has been shown to contribute, promote, and speed up acrylamide formation in baked products.
A proposed mechanism is that NH₄HCO₃ fragments sugars, forming the highly reactive glyoxal and methylglyoxal species, which can react with asparagine, thereby increasing acrylamide levels.
Ammonium bicarbonate (ABC) is an important raising agent for the biscuit and cracker industry and bakers also useAmmonium bicarbonate in some strongly flavored products like gingerbread.

Ammonium bicarbonate decomposes on heating at 60°C in a temperature-driven reaction releasing carbon dioxide, ammonia, and water vapor.
Ammonium bicarbonate offers major technical benefits, as Ammonium bicarbonate is used for rapid, early expansion in the oven.
Since Ammonium bicarbonate does not start acting before the oven, Ammonium bicarbonate means that products do not gas when the dough ismixing or standing which can be important during plant breakdowns.

Biscuit makers also value the consistent stack height Ammonium bicarbonate gives, and Ammonium bicarbonate leaves no residue and no adverse flavors in low moisture products.
Another complexity revolves around the fact that the level added to a recipe may change daily because of normal raw material variations.

In this situation using Ammonium bicarbonate allows the adaptation of only one, standalone, ingredient, whereas other raising agents—that require acids for their action—would be more complicated to adapt.
Unfortunately, the tendency to promote acrylamide formation is now a major drawback of using ABC.

Uses of Ammonium bicarbonate:

Ammonium bicarbonate is used as a baking powder, in some food processing applications, in cough syrups and as antacid.
Ammonium bicarbonate also has uses as a fertilizer, pH buffer, and reagent in chemical laboratories.
In the industry, Ammonium bicarbonate is used in the manufacture of dyes, pharmaceuticals, catalysts, ceramics,fire retardants, plastics and other products.

Health effects/safety hazards:

In low concentrations, Ammonium bicarbonate is not considered hazardous.
Ammonium bicarbonates main health hazard is Ammonium bicarbonates decomposition reaction giving pungent ammonia gas, which is a serious irritant.
Inhalation of ammonium bicarbonate can irritate the eyes, skin, nose and entire respiratory system, and cause severe coughing and difficulty in breathing.

Ammonium bicarbonate is a uniform high purity leavening agent, produced by a chemical reaction of ammonia, carbondioxide and water.
Ammonium bicarbonate has a very strong scent and because of this is used primarily used to leaven only low.moisture baked goods like crisp cookies and crackers that thoroughly dry out during baking.

Ammonium bicarbonate is not used to make cakes because the ammonia gas cannot evaporate when baking cake or other large Ammonium bicarbonateems.
When using ammonium bicarbonate instead of baking soda to bake crisp cookies, the ammonium bicarbonate produces a lighter, crunchy texture.



DESCRIPTION


Ammonium bicarbonate is a white crystalline solid having the odor of ammonia.
Ammonium bicarbonate is soluble in water.

Ammonium Bicarbonate appears as a white crystal or crystalline powder.
Ammonium bicarbonate volatilizes rapidly at 60 °C, dissociating into ammonia, carbon dioxide, and water, but Ammoniumbi carbonate is quite stable at room temperature.

One gram dissolves in about 6 ml of water.
Ammonium bicarbonate is insoluble in alcohol.

The primary hazard is the threat to the environment.
Immediate steps should be taken to limit spread to the environment.
Ammonium bicarbonate is used to make other ammonium compounds, in food processing, and for other uses.

Some properties of Ammonium bicarbonate:

Colorless or white crystals
Faint odor of ammonia
Melting point: 95 °F (35 °C)
Freely soluble in water.
Insoluble in ethanol
Decomposes above 34 °C with formation of ammonia gas


When heated Ammonium bicarbonate releases ammonia and carbon dioxide gases, but no water.
The lack of water allows the cookies to cook and dry out faster.
Ammonium bicarbonate may also be used as a substitute to remove the alkaline-like flavor that at times occurs in some baked goods when baking powder or baking soda is added.
Many older European and Scandinavian recipes may use the term Baker's Ammonia instead of Ammonium Biocarbonate when referring to this substance.

Ammonium bicarbonate is also often referred to as Hartshorn or Harts Horn which is a substance that is removed from deerantlers.
Ammonium bicarbonate is important to understand that Ammonia and leaving agents such as Baker's Ammonia, baking powder or baking soda are not the same as household ammonia which is a poisonous substance and should not be used with foods or baked goods.
Ammonium bicarbonate is activated when Ammonium bicarbonate is added to a dough or batter mixture and warms to room temperature or is baked, since heat is the catlyst to activate the chemical reaction and the gases.

The chemical reaction releases an ammonia gas that causes the baked goods to rise.
Ammonium Biocarbonate should be stored in an air tight sealed container such as a glass jar with an airtight lid.
An inorganic compound, Ammonium bicarbonate is used in the food industry as a raising agent for flat baked goods, such as cookies and crackers.

Ammonium bicarbonate also has uses as a fertiliser, pH buffer, and reagent in chemical laboratories.
Some other uses of Ammonium bicarbonate in the industry are for the manufacture of dyes, pharmaceuticals, catalysts, ceramics, fire retardants, plastics and other products.

Ammonium bicarbonate appears as white monoclinic or orthorhombic crystals.
Ammonium bicarbonate is soluble in water, but insoluble in ethanol, carbon disulfide and concentrated ammonia.

Ammonium bicarbonate dissolves in water to give a mildly alkaline solution.
Ammonium bicarbonate is insoluble in most organic solvents.

Ammonium bicarbonate is mainly used as fertilizers.
After being applied to the soil, the ammonium ion (NH4 +) contained in ammonium bicarbonate can be absorbed by soilcolloid or lattice fixed or transformed into nitrate nitrogen.
After being absorbed by plants, there are no accessory constituents remaining in the soil with a small impact on the soil pH.

Ammonium bicarbonate is applicable to all kinds of soil and crops, soil without leaving any harmful substance residue for the soil and crops.
Ammonium bicarbonate is quick-acting nitrogen fertilizer and can be subject to long term usage.
In order to prevent the loss of fertilizer efficacy due to ammonia volatilization and the burning of the crop stems and leaves, we can apply deep placement and cover soil.

Ammonium bicarbonate is an inorganic compound with bicarbonate formula (NH4)HCO3, simplified to NH5CO3.
Ammonium bicarbonate has many names, reflecting Ammonium bicarbonate's long history.

Chemically speaking, Ammonium bicarbonate is the bicarbonate salt of the ammonium ion.
Ammonium bicarbonate is a colourless solid that degrades readily to carbon dioxide, water and ammonia.

Ammonium bicarbonate used as Raising agent for cookies and flatbreads
Ammonium bicarbonate is used as a leavening / raising agent in the food industry.
Ammonium bicarbonate contains ammonium bicarbonate with the addition of magnesium carbonate as an anti-caking agent.

Ammonium bicarbonate is a white powder that is readily soluble in water.
Ammonium bicarbonate is used as a nutritional supplement in the animal feed industry.
Ammonium bicarbonate is a white powder that is readily soluble in water.


Ammonium bicarbonate will decompose during baking and release ammonia and carbon dioxide leavening gases without reacting with a leavening acid.
Unlike sodium bicarbonate, which leaves a residue of alkaline sodium carbonate, ammonium bicarbonate leaves no residue when Ammonium bicarbonate decomposes by heat.
Ammonium bicarbonate, therefore, has no effect on the pH of the baked product.

If there is more than about 5% moisture in the baked product, however, the ammonia gas will dissolve in this water and impart an ammoniacal flavor to the product.
For this reason, ammonium bicarbonate is used only in low moisture products such as crackers.
Ammonium Bicarbonate (or baking ammonia or hartshorn salt) is used as a leavening agent in baking of cookies and other edible treats.

Ammonium bicarbonate, a natural chemical, has a faint ammonia smell because Ammonium bicarbonate slowly decomposes to ammonia, carbon dioxide, and water.
As a pesticide active ingredient, Ammonium bicarbonate acts as a feeding attractant for insects.

In Ammonium bicarbonates first approved end use products, ammonium bicarbonate is combined with two other active ingredients to control olive flies in olive orchards.
When used according to label directions on products, Ammonium bicarbonate is not expected to harm people or the environment.

Ammonium bicarbonate gives an explosive and fast leavening for baked goods that are baked for a short time.
Ammonium bicarbonate is specially suitable for thin, dry cookies.

Ammonium Bicarbonate is a widely used ingredient in bakery industry because of Ammonium bicarbonates leavening and stabilizing properties and acid regulating capacity.



PROPERTIES


Molecular Weight: 79.056
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 0
Exact Mass: 79.026943022
Monoisotopic Mass: 79.026943022
Topological Polar Surface Area: 61.4 Ų
Heavy Atom Count: 5
Formal Charge: 0
Complexity: 24.8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
Boiling Point: N/A
Specific gravity: N/A
Appearance / Odor: white crystalline powder
Melting Point: 41.9 °C (107.4 °F)
pH: 8.2 at 1 percent solution
Molecular Weight: 79.05
Formula: CH5NO3 / NH4HCO3
Molecular mass: 79.1
Decomposes at 35.60°C
Density: 1.58 g/cm³
Solubility in water, g/100ml at 20°C: 17.4 (good)



SAFETY


Ammonium bicarbonate is an irritant to the skin, eyes and respiratory system.
Short-term health effects may occur immediately or shortly after exposure to ammonium bicarbonate.
Breathing ammonium bicarbonate can irritate the nose, throat and lungs causing coughing, wheezing and/or shortness of breath.

Repeated exposure may cause bronchitis to develop with cough, and/or shortness of breath. Health effects can occur some time after exposure to ammonium bicarbonate and can last for months or years.

Where possible, operations should be enclosed and the use of local exhaust ventilation at the site of chemical release is recommended.
If local exhaust ventilation or enclosure is not used, respirators are necessary.
Wear protective work clothing and change clothes and wash thoroughly immediately after exposure to ammonium bicarbonate.

Ammonium bicarbonate from China used to make cookies was found to be contaminated with melamine, and imports were banned in Malaysia following the 2008 Chinese milk scandal.



HANDLING AND STORAGE


When properly stored in a cool dry area, Ammonium Bicarbonate can last for several years.
If stored in a warm or damp area where air can reach the powder, this substance begins to clump together as the particles got hrough a chemical reaction, which will affect the flavor adversely when baked goods use the air exposed Bicarbonate.
In addition, when exposed to air, the Ammonia may begin to evaporate from the powdered Bicarbonate substance.

When a recipe suggests the use of Ammonium Bicarbonate, equal amounts of baking powder can be substituted if necessary.
To determine if Bicarbonate is still active, add a spoonful of the powder to a cup containing lemon juice or vinegar and see if Ammonium bicarbonate fizzes.

Stale Ammonium bicarbonate will be flat and will not fizz when combined with the vinegar or lemon juice.
If you don't store Ammonium bicarbonate in an airtight jar Ammonium bicarbonate will evaporate.



SYNONYMS


AMMONIUM BICARBONATE
1066-33-7
Ammonium hydrogencarbonate
Ammonium hydrogen carbonate
Monoammonium carbonate
Carbonic acid, monoammonium salt
Ammonium bicarbonate (1:1)
azanium;hydrogen carbonate
Carbonic acid, ammonium salt (1:1)
ammoniumcarbonate
MFCD00012138
45JP4345C9
carbonic acid monoammonium salt
Acid ammonium carbonate
Ammonium acid carbonate
Ammonium hydrogencarbonat
CCRIS 7327
HSDB 491
10361-29-2
EINECS 213-911-5
UNII-45JP4345C9
EC 213-911-5
INS NO.503(II)
DTXSID5035618
INS-503(II)
AMMONIUM BICARBONATE [MI]
CHEBI:184335
AMMONIUM BICARBONATE [FCC]
AMMONIUM BICARBONATE [HSDB]
AMMONIUM BICARBONATE [INCI]
AMMONIUM BICARBONATE [MART.]
E 503(II)
E-503(II)
AMMONIUM BICARBONATE [WHO-DD]
AKOS016008582
FT-0622308
AMMONIUM HYDROGEN CARBONATE [EP MONOGRAPH]
J-610004
AMMONIUM BIFLUORIDE
Ammonium Bifluoride (Amonyum Biflorür) IUPAC Name azanium;fluoride;hydrofluoride Ammonium Bifluoride (Amonyum Biflorür) InChI InChI=1S/2FH.H3N/h2*1H;1H3 Ammonium Bifluoride (Amonyum Biflorür) InChI Key KVBCYCWRDBDGBG-UHFFFAOYSA-N Ammonium Bifluoride (Amonyum Biflorür) Canonical SMILES [NH4+].F.[F-] Ammonium Bifluoride (Amonyum Biflorür) Molecular Formula F2H5N Ammonium Bifluoride (Amonyum Biflorür) CAS 1341-49-7 Ammonium Bifluoride (Amonyum Biflorür) Related CAS 12125-01-8 (Parent) Ammonium Bifluoride (Amonyum Biflorür) Deprecated CAS 120144-37-8, 127026-25-9 Ammonium Bifluoride (Amonyum Biflorür) European Community (EC) Number 215-676-4 Ammonium Bifluoride (Amonyum Biflorür) UN Number 1727 Ammonium Bifluoride (Amonyum Biflorür) UNII C2M215358O Ammonium Bifluoride (Amonyum Biflorür) DSSTox Substance ID DTXSID9029645 Ammonium Bifluoride (Amonyum Biflorür) Physical Description DryPowder; OtherSolid; OtherSolid, Liquid; PelletsLargeCrystals Ammonium Bifluoride (Amonyum Biflorür) Color/Form Rhombic or tetragonal crystals Ammonium Bifluoride (Amonyum Biflorür) Odor Odorless Ammonium Bifluoride (Amonyum Biflorür) Boiling Point 240 °C Ammonium Bifluoride (Amonyum Biflorür) Melting Point 125.6 °C Ammonium Bifluoride (Amonyum Biflorür) Solubility Solubility in 90% ethanol = 1.73X10+5 mg/L Ammonium Bifluoride (Amonyum Biflorür) Density 1.50 g/cu cm Ammonium Bifluoride (Amonyum Biflorür) Corrosivity Will etch glass Ammonium Bifluoride (Amonyum Biflorür) Heat of Vaporization 65.3 kJ/mol Ammonium Bifluoride (Amonyum Biflorür) pH 3.5 (5% solution) Ammonium Bifluoride (Amonyum Biflorür) Refractive Index Index of refraction = 1.390 Ammonium Bifluoride (Amonyum Biflorür) Molecular Weight 57.044 g/mol Ammonium Bifluoride (Amonyum Biflorür) Hydrogen Bond Donor Count 2 Ammonium Bifluoride (Amonyum Biflorür) Hydrogen Bond Acceptor Count 2 Ammonium Bifluoride (Amonyum Biflorür) Rotatable Bond Count 0 Ammonium Bifluoride (Amonyum Biflorür) Exact Mass 57.039005 g/mol Ammonium Bifluoride (Amonyum Biflorür) Monoisotopic Mass 57.039005 g/mol Ammonium Bifluoride (Amonyum Biflorür) Topological Polar Surface Area 1 Ų Ammonium Bifluoride (Amonyum Biflorür) Heavy Atom Count 3 Ammonium Bifluoride (Amonyum Biflorür) Formal Charge 0 Ammonium Bifluoride (Amonyum Biflorür) Complexity 0 Ammonium Bifluoride (Amonyum Biflorür) Isotope Atom Count 0 Ammonium Bifluoride (Amonyum Biflorür) Defined Atom Stereocenter Count 0 Ammonium Bifluoride (Amonyum Biflorür) Undefined Atom Stereocenter Count 0 Ammonium Bifluoride (Amonyum Biflorür) Defined Bond Stereocenter Count 0 Ammonium Bifluoride (Amonyum Biflorür) Undefined Bond Stereocenter Count 0 Ammonium Bifluoride (Amonyum Biflorür) Covalently-Bonded Unit Count 3 Ammonium Bifluoride (Amonyum Biflorür) Compound Is Canonicalized Yes Ammonium Bifluoride (Amonyum Biflorür) is the inorganic compound with the formula NH4HF2 or NH4F·HF. It is produced from ammonia and hydrogen fluoride. This colourless salt is a glass-etchant and an intermediate in a once-contemplated route to hydrofluoric acid.Ammonium Bifluoride (Amonyum Biflorür), as its name indicates, contains an ammonium cation (NH4+) and a bifluoride, or hydrogen(difluoride), anion (HF2−). The centrosymmetric triatomic bifluoride anion features the strongest known hydrogen bond, with a F−H length of 114 pm. and a bond energy greater than 155 kJ mol−1.Ammonium Bifluoride (Amonyum Biflorür) is also used as an additive in tin-nickel plating processes as the fluoride ion acts as a complexing agent with the tin, allowing for greater control over the resulting composition and finish.Ammonium Bifluoride (Amonyum Biflorür) is toxic to consume and a skin corrosion agent. Upon exposure to skin, rinsing with water followed by a treatment of calcium gluconate is required. Poison control should be contacted.Anhydrous Ammonium Bifluoride (Amonyum Biflorür) containing 0.1 5 H2O and 93% NH4HF2 can be made by dehydrating ammonia fluoride solutions and by thermally decomposing the dry crystals. Commercial Ammonium Bifluoride (Amonyum Biflorür), which usually contains 1% NH4F, is made by gas phase reactions of one mole of anhydrous ammonia with two moles of anhydrous hydrogen fluoride; the melt that forms is flaked on a cooled drum.Ammonium Bifluoride (Amonyum Biflorür) soln should be thoroughly washed from the skin with mildly alkaline soap as soon as possible.Ammonium Bifluoride (Amonyum Biflorür) is an indirect food additive for use only as a component of adhesives.Ammonium hydrogen fluoride* (NH4HF2) is used for aluminium anodization, metal surface treatment, manufacture of wood preservatives, glass processing, building protection, mineral oil/ natural gas drilling, cleaning of industrial plants and in the electronic industry. Ammonium Bifluoride (Amonyum Biflorür) is used in the the following applications: Glass processing: for matt etching Metal surface treatment: as essential component of bright digo baths for etching and cleaning of non-ferrous metal pieces Mineral oil / natural gas drilling: as aid for drilling through silicate rocks Cleaning of industrial plants: as component in cleaning and disinfecting solutions, e.g. in power stations Building protection: as component in cleaning agents *Goods labelled as “dual use” are subject to special controls and export restrictions in most countries. Before exporting such goods the exporter must apply for an appropriate export licence from the competent authority. For deliveries within the EU, for example, the seller must include an appropriate note in the commercial papers in accordance with article 22, paragraph 10, of the dual use regulation.Ammonium Bifluoride (Amonyum Biflorür) is a reagent widely used in organic synthesis; however, the systematic collection and classification have not been covered until now.In this review, we aim to systematically summarize the application of Ammonium Bifluoride (Amonyum Biflorür) in organic synthesis.Ammonium Bifluoride (Amonyum Biflorür), Flake is an inorganic compound that is a colorless salt that is used as a glass etchtant. It is produced from ammonia and hydrogen fluoride.The aim of the study was to discuss clinical effects, treatment options and outcomes of pediatric Ammonium Bifluoride (Amonyum Biflorür) (ABF) poisoning.Dissolution of geological reference materials by fusion with Ammonium Bifluoride (Amonyum Biflorür), NH{sub 4}HF{sub 2} or ABF, was evaluated for its potential use in post-detonation nuclear forensics. The fluorinating agent Ammonium Bifluoride (Amonyum Biflorür) (ABF) is a potential field deployable substitute for HF.Ammonium Bifluoride (Amonyum Biflorür) (ABF, NH4F·HF) is a well-known reagent for converting metal oxides to fluorides and for its applications in breaking down minerals and ores in order to extract useful components.The process involves the use of a hitherto unknown solid‐state chemical reaction between Ammonium Bifluoride (Amonyum Biflorür) and specific anhydrous and hydrated metal fluoride salts.It was observed that these complexes decompose with the evolution of HF above temperatures at which Ammonium Bifluoride (Amonyum Biflorür) decomposes and where its supply may be exhausted.Ammonium Bifluoride (Amonyum Biflorür) (ABF) is one of the most common, and dangerous, wheel cleaners used in automatic carwashes today.Hydrogen fluoride and Ammonium Bifluoride (Amonyum Biflorür). Ammonium Bifluoride (Amonyum Biflorür) are created for industrial use only.Ammonium Bifluoride (Amonyum Biflorür) solution is the white crystalline solid dissolved in water. It is corrosive to metals and tissue. It is used in ceramics.Ammonium Bifluoride (Amonyum Biflorür) is a white, solid that consists of crystals or flakes with a pungent odor. Ammonium Bifluoride (Amonyum Biflorür) can cause severe necrosis to tissue, with symptoms such as redness, itching, burns and scarring. Ammonium Bifluoride (Amonyum Biflorür) can cause a unique, large, pustular skin rash, which is apparently not an irritant or allergic dermatitis.Ammonium Bifluoride (Amonyum Biflorür) may be systematically absorbed in lethal amounts through intact skin. Effects may be delayed and not felt for hours.All contact with Ammonium Bifluoride (Amonyum Biflorür) must be avoided during clean-up.Ammonium Bifluoride (Amonyum Biflorür) is a respiratory tract irritant, and inhalation may cause nose irritation,sore throat, coughing, and chest tightness and possibly, ulceration and perforation of the nasal septum.Ammonium Bifluoride (Amonyum Biflorür) can be absorbed through intact skin in lethal amounts.Ammonium Bifluoride (Amonyum Biflorür) and hydrofluoric acid are potent toxins with severe local and systemic toxicity due to high permeability coefficient and binding of divalent cations with disruption of the Na-K-ATPase pump.The first SDS stated the product was a proprietary formula with Ammonium Bifluoride (Amonyum Biflorür)s and 1-2% hydrofluoric acid. A more specific SDS was located and which showed 21-27% Ammonium Bifluoride (Amonyum Biflorür) and a small amount of barium sulfate in the product. This corresponds to 17-23 g of Ammonium Bifluoride (Amonyum Biflorür) in a 3 ounce ingestion.Results are given for elevated temperature tests of the effects of Ammonium Bifluoride (Amonyum Biflorür) on corrosion rates of 5 and 10% solutions of inhibited citric, sulfamic, hydrochloric, and phosphoric acid scale solvents. Mild steel coupons were evaluated for weight loss after 12 hr exposures. The rate of attack for citric and sulfamic acid systems on steel decreased as concentration of Ammonium Bifluoride (Amonyum Biflorür) increased. The attack rate of HCL increased at lower Ammonium Bifluoride (Amonyum Biflorür) concentrations, but at higher concentrations tended to stabilize at a rate equivalent to that from 5% acid without Ammonium Bifluoride (Amonyum Biflorür). The rate of 5% phosphoric acid attack decreased with increased concentration of Ammonium Bifluoride (Amonyum Biflorür), but in 10% phosphoric acid, the rate increased with increased concentration of Ammonium Bifluoride (Amonyum Biflorür). It is hypothesized that in citric and sulfamic acids the ammonium ion is inhibitive, but that in the more aggressive hydrochloric and phosphoric acids, the corrosion rates do not hold a relationship with Ammonium Bifluoride (Amonyum Biflorür) concentrations.Ammonium hydrogen fluoride is the inorganic compound with the formula NH4HF2 or NH4F·HF. It is produced from ammonia and hydrogen fluoride. This colourless salt is a glass-etchant and an intermediate in a once-contemplated route to hydrofluoric acid.Ammonium bifluoride, as its name indicates, contains an ammonium cation (NH4+) and a bifluoride, or hydrogen(difluoride), anion (HF2−). The centrosymmetric triatomic bifluoride anion features the strongest known hydrogen bond, with a F−H length of 114 pm. and a bond energy greater than 155 kJ mol−1.In solid [NH4][HF2], each ammonium cation is surrounded by four fluoride centers in a tetrahedron, with hydrogen-fluorine hydrogen bonds present between the hydrogen atoms of the ammonium ion and the fluorine atoms.[citation needed] Solutions contain tetrahedral [NH4]+ cations and linear [HF2]− anions.Ammonium bifluoride has been considered as an intermediate in the production of hydrofluoric acid from hexafluorosilicic acid. Thus, hexafluorosilicic acid is hydrolyzed to give ammonium fluoride, which thermally decomposes to give the bifluoride:H2SiF6 + 6 NH3 + 2 H2O → SiO2 + 6 NH4F 2 NH4F → NH3 + [NH4]HF2 The resulting ammonium bifluoride is converted to sodium bifluoride, which thermally decomposes to release HF.Ammonium bifluoride is also used as an additive in tin-nickel plating processes as the fluoride ion acts as a complexing agent with the tin, allowing for greater control over the resulting composition and finish.Ammonium bifluoride is toxic to consume and a skin corrosion agent. Upon exposure to skin, rinsing with water followed by a treatment of calcium gluconate is required.Ammonium hydrogen fluoride* (NH4HF2) is used for aluminium anodization, metal surface treatment, manufacture of wood preservatives, glass processing, building protection, mineral oil/ natural gas drilling, cleaning of industrial plants and in the electronic industry. Ammonium hydrogen fluoride is used in the the following applications: Glass processing: for matt etching Metal surface treatment: as essential component of bright digo baths for etching and cleaning of non-ferrous metal pieces Mineral oil / natural gas drilling: as aid for drilling through silicate rocks Cleaning of industrial plants: as component in cleaning and disinfecting solutions, e.g. in power stations Building protection: as component in cleaning agents *Goods labelled as “dual use” are subject to special controls and export restrictions in most countries. Before exporting such goods the exporter must apply for an appropriate export licence from the competent authority. For deliveries within the EU, for example, the seller must include an appropriate note in the commercial papers in accordance with article 22, paragraph 10, of the dual use regulation.Fluorides are absorbed from GI tract, lung, & skin. GI tract is major site of absorption. The relatively sol cmpd, such as sodium fluoride, are almost completely absorbed ... Fluoride has been detected in all organs & tissues examined ... There is no evidence that it is concentrated in any tissues except bone, thyroid, aorta, & perhaps kidney. Fluoride is preponderantly deposited in the skeleton & teeth, & the degree of skeletal storage is related to intake and age. ... A function of the turnover rate of skeletal components, with growing bone showing greater fluoride deposition than bone in mature animals. ... Major route of ... excretion is by way of kidneys ... also excreted in small amt by sweat glands, lactating breast, & GI tract. ... About 90% of fluoride ion filtered by glomerulus is reabsorbed by renal tubules.Following ingestion, soluble fluorides are rapidly absorbed from the gastrointestinal tract at least to the extent of 97%. Absorbed fluoride is distributed throughout the tissues of the body by the blood. Fluoride concentrations is soft tissues fall to pre-exposure levels within a few hours of exposure. Fluoride exchanges with hydroxyl radicals of hydroxyapatite (the inorganic constituent of bone) to form fluorohydroxyapatite. Fluoride that is not retained is excreted rapidly in urine. In adults under steady state intake conditions, the urinary concentration of fluoride tends to approximate the concentration of fluoride in the drinking water. This reflects the decreasing retention of fluoride (primarily in bone) with increasing age. Under certain conditions perspiraton may be an important route of fluoride excretion. The concentration of fluoride retained in bones and teeth is a function of both the concentration of fluoride intake and the duration of exposure. Periods of excessive fluoride exposure will result in increased retention in the bone. However, when the excessive exposure is eliminated, the bone fluoride concentration will decrease to a concentration that is again reflective of intake.Inhibition of one or more enzymes controlling cellular glycolysis (and perhaps resp) may result in a critical lesion. ... Binding or precipitation of calcium as calcium fluoride ... suggested as mechanism underlying many diverse signs and symptoms in fluoride poisoning, particularly if death is delayed. ... At least in some species fluoride interferes with both contractile power of heart and the mechanism of beat in a way that cannot be ascribed to hypocalcemia.The mechanism for acute lethality at high fluoride dose levels is not fully defined. It is believed that certain essential enzymatic reactions may be blocked and there may be interference with the origin and transmission of nerve impulses. The metabolic roles of calcium and physical damage to the kidney and the mucosa of the stomach and intestine are also believed to be associated with the acute lethality mechanism. Fluoride interacts with bones and teeth by replacing hydroxyl or bicarbonate ions in hydroxyapatite to form fluorohydroxyapatite. Fluoride may function as an essential key to bring about precipitation or nucleation of the apatite lattice in an oriented fashion on collagen fibers. Accretion of new mineral continues, and fluoride, brought to the surfaces of newly formed crystals by the extracellular fluid, replaces the hydroxyl ion. As crystal growth continues, fluoride is incorporated into inner layers of the crystals as well as on the surface. Remodeling of the bone structure takes place by an interplay of osteoclastic resorption of old bone and osteoblastic deposition of new bone. The presence of fluorohydroxyapatite increases the crystalline structure of the bone and reduces its solubility. Available evidence suggests that dental fluorosis results from toxic effects of fluoride on the epithelial enamel organ. Specifically, several investigators have shown that ameloblasts are susceptible to fluoride. Dental staining often accompanies fluorosis but does not itself determine the degree of fluorosis. The staining is believed to be due to the oxidation of organic material in defective enamel or the penetration of hypoplastic sections of enamel by food pigments.Manufacture of magnesium and magnesium alloys; in brightening of aluminum; for purifying and cleansing various parts of beer-dispensing apparatus, tubes, etc., sterilizing dairy and other food equipment; in glass and porcelain industries; as mordant for aluminum; as a "sour" in laundering cloth. In lab production of hydrogen fluoride.Anhydrous ammonium bifluoride containing 0.1 5 H2O and 93% NH4HF2 can be made by dehydrating ammonia fluoride solutions and by thermally decomposing the dry crystals. Commercial ammonium bifluoride, which usually contains 1% NH4F, is made by gas phase reactions of one mole of anhydrous ammonia with two moles of anhydrous hydrogen fluoride; the melt that forms is flaked on a cooled drum.Fluoride- Electrode Method. This method is suitable for fluoride concn from 0.1 to more than 10 mg/l. The fluoride electrode is a selective ion sensor. The key element in the fluoride electrode is the laser-type doped lanthanum fluoride crystal across which a potential is lished by fluoride soln of different concn. The crystal contacts the sample soln at one face and an internal reference soln at the other. The fluoride electrode measures the ion activity of fluoride in soln rather than concn. Fluoride ion activity depends on the soln total ionic strength and pH, and on fluoride complexing species. Adding an appropriate buffer provides a uniform ionic strength background, adjusts pH, and breaks up complexes so that, in effect, the electrode measures concn. A synthetic sample containing 0.850 mg fluoride ion/l in distilled water was analyzed in 111 laboratories with relative standard deviation of 3.6% and relative error of 0.7%.Fluoride- SPADNS Method. This method is suitable only for concn in the range of 0.05 to 1.4 mg/l. The reaction rate between fluoride and zirconium ion is influenced greatly by the acidity of the reaction mixture. If the proportion of acid in the reagent is incr, the reaction can be made almost instantaneous. Under such conditions, however, the effect of various ions differs from that in the conventional alizarin method. The selection of dye for this rapid fluoride method is governed largely by the resulting tolerance to these ions. A synthetic sample contanining 0.830 mg fluoride ion/l and no interference in distilled water was analyzed in 53 laboratories with a relative standard deviation of 8.0% and a relative error of 1.2%. After direct distillation of the sample, the relative standard deviation was 11.0% and the relative error 2.4%. Ammonium bifluoride (NH4•HF2) is manufactured and sold in solid form or in aqueous solutions. The solid is a white crystal. The solutions are clear, colorless liquids that have a slightly sharp, pungent odor. Common industrial solution strength concentrations for Ammonium Bifluoride are between 28 and 30%. Ammonium bifluoride (ABF) Ammonium difluoride Ammonium acid fluoride Ammonium hydrogen difluoride Ammonium fluoride compound with hydrogen fluoride (1:1) Ammonium Bifluoride Flakes are used for aluminium anodization, metal surface treatment, manufacture of wood preservatives, glass processing, mineral oil/ natural gas drilling, cleaning agents of industrial plants, breweries and in the electronics industry. It may also be used for pH adjustment in industrial textile processing or laundries. ABF is available as a solid or liquid solution (in water). Background: Ammonium bifluoride is a reagent widely used in organic synthesis; however, the systematic collection and classification have not been covered until now. Methodology: In this review, we aim to systematically summarize the application of ammonium bifluoride in organic synthesis. Conclusion: It can be used for deprotection of hydroxyl protected groups (esp. Silyl protection). It is also used for introducing F & N atoms into organic molecules; promoting cyclization reactions acting as a multifunctional reagent. AMMONIUM BIFLUORIDE reacts violently with bases. In presence of moisture will corrode glass, cement, and most metals. Flammable hydrogen gas may collect in enclosed spaces. Do not use steel, nickel, or aluminum containers (USCG, 1999). Ammonium bifluoride (ABF) is one of the most common, and dangerous, wheel cleaners used in automatic carwashes today. Its effectiveness removing brake dust and difficult contaminants from chrome wheels is undisputed, but some chemists say ABF presents an unjustifiable and potentially lethal risk to carwash operators and their employees. Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Use water in flooding quantities as fog. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible.Environmental considerations- land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash or cemented powder. Neutralize with agricultural lime (CaO), crushed limestone (CaCO3) or sodium bicarbonate (NaHCO3). Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water.Environmental considerations- water spill: Neutralize with agricultural lime (CaO), crushed limestone (CaCO3), or sodium bicarbonate (NaHCO3). Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.If material not involved in fire: Keep material out of water sources and sewers. Build dikes to contain flow as necessary. Use water spray to knock-down vapors. Neutralize spilled material with crushed limestone, soda ash, or lime.Avoid breathing vapors. Keep upwind. Avoid bodily contact with the material. Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. Avoid breathing fumes from burning material.The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.Health: TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. /Ammonium bifluoride, solid; Ammonium bifluoride, solution/No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations .The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.Ammonium bifluoride is designated as a hazardous substance under section 311(b)(2)(A) of the Federal Water Pollution Control Act and further regulated by the Clean Water Act Amendments of 1977 and 1978. These regulations apply to discharges of this substance. This designation includes any isomers and hydrates, as well as any solutions and mixtures containing this substance.Maintain an open airway and assist ventilation if necessary. Monitor ECG and serum calcium, magnesium, and potassium for at least 4 to 6 hours. Admit symptomatic patients with ECG or electrolyte abnormalities to an intensive care setting. When clinically significant hypocalcemia is present, administer intravenous calcium gluconate ... and monitor ionized calcium levels and titrate further doses as needed. Treat hypomagnesemia with intravenous magnesium sulfate... . Treat hypokalemia with intravenous calcium and other usual measures. Do not induce vomiting because of the risk of abrupt onset of seizures and arrhythmias. Administer an antacid containing calcium (eg, calcium carbonate) orally to raise gastric pH and complex free fluoride, reducing absorption. Foods rich in calcium (eg, milk) can also bind fluoride. Magnesium-containing antacids have also been recommended but there are little data for their effectiveness. ... Consider gastric lavage for recent large ingestions. Activated charcoal does not absorb fluoride and is not likely to be beneficial. Because fluoride rapidly binds to free calcium and bone and has a short elimination half-life, hemodialysis is not likely to be effective.Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures adn treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool. ... . Cover skin burns with dry sterile dressings after decontamination . Most available toxicity information on fluoride relates to acute toxicity of hydrofluoric acid (''HF''). However, other water soluble fluoride-containing compounds can cause fluoride poisoning. The fluoride ion is systemically absorbed almost immediately. It is highly penetrating and reactive and can cause both systemic poisoning and tissue destruction. Fluoride ions, once separated from either HF or fluoride salts, penetrate deep into tissues, causing burning at sites deeper than the original exposure site. The process of tissue destruction can continue for days. Fluoride absorption can produce hyperkalemia (elevated serum potassium), hypocalcemia (lowered serum calcium), hypomagnesemia (lowered serum magnesium), and metabolic and respiratory acidosis. These disturbances can then bring on cardiac arrhythmia, respiratory stimulation followed by respiratory depression, muscle spasms, convulsions, central nervous system (''CNS'') depression, possible respiratory paralysis or cardiac failure, and death. Fluoride may also inhibit cellular respiration and glycolysis, alter membrane permeability and excitability, and cause neurotoxic and adverse GI effects. When exposure is through inhalation, fluorides can cause severe chemical burns to the respiratory system. Inhalation can result in difficulty breathing (dyspnea), bronchospasms, chemical pneumonitis, pulmonary edema, airway obstruction, and tracheobronchitis. The severity of burns from dermal absorption can vary depending on the concentration of fluoride available, duration of the exposure, the surface area exposed, and the penetrability of the exposed tissue. Ocular exposure can result in serious eye injury. Ingestion of fluoride can result in mild to severe GI symptoms. Reports suggest that ingesting 3 to 5 milligrams of fluoride per kilogram of body weight (mg/kg) causes vomiting, diarrhea, and abdominal pain. Ingestion of more than 5 mg/kg may produce systemic toxicity. A retrospective poison control center study of fluoride ingestions reported that symptoms, primarily safely tolerated GI symptoms that tended to resolve within 24 hours, developed following ingestions of 4 to 8.4 mg/kg of fluoride.