Paint, Construction, Plastics, Rubber Chemicals

POTASSIUM SULFATE
Potassium sulfate, with the chemical formula K2SO4, is an inorganic chemical compound and a necessary nutrient source for plants.
Potassium sulfate is soluble in water but insoluble in ethanol.
Potassium sulfate is primarily used as a fertilizer to improve crop yields.

CAS Number: 7778-80-5
EC Number: 231-915-5
Molecular Formula: K2O4S
Molecular Weight (g/mol): 174.25

Synonyms: Potassium sulfate, 7778-80-5, DiPotassium sulfate, Potassium sulphate, Sulfuric acid dipotassium salt, Sulfuric acid, potassium salt, Arcanum duplicatum, Sulfuric acid, dipotassium salt, Potassiumsulfate, dipotassium;sulfate, Tartarus vitriolatus, Kali sulphuricum, Potassium sulfate (2:1), K2SO4, Potassium (as sulfate), MFCD00011388, Sulfuric acid potassium salt (1:2), 10233-01-9, 1K573LC5TV, INS NO.515(I), CHEBI:32036, INS-515(I), E-515(I), Kalium sulphuricum, Caswell No. 702, Potassium sulfate [JAN], Sulfato de potasio, Potassium sulfate (K2(SO4)), HSDB 5047, EINECS 231-915-5, EINECS 233-558-0, EPA Pesticide Chemical Code 005603, Sulfuric acid potassium salt, UNII-1K573LC5TV, Kaliumsulfat, Potassium sulfate, ACS, Potassium sulfate [USAN:JAN], Sulfate of Potash, Potassium sulfate ,(S), EC 231-915-5, Potassium sulfate (K2SO4), Potassium sulfate [MI], KALI SULPHURICUM [HPUS], Potassium sulfate [FCC], CHEMBL2021424, DTXSID6029701, Potassium sulfate [HSDB], Potassium sulfate [INCI], Potassium sulfate [USAN], Potassium sulfate (JP17/USAN), Potassium sulfate [VANDF], Potassium sulfate [MART.], Potassium sulfate [WHO-DD], BLI801 Component Potassium sulfate, Potassium sulfate, Biochemical grade, BLI-801 Component Potassium sulfate, AKOS025243249, Sulfuric acid, potassium salt (1:?), DB14499, Potassium sulfate [ORANGE BOOK], POTASSIUM (AS SULFATE) [VANDF], Potassium sulfate [EP MONOGRAPH], Potassium sulphate, containing in the dry state more than 52 per cent by weight of K2O, FisherTab™ MT-37 Kjeldahl Tablets, FisherTab™ ST-35 Kjeldahl Tablets, FisherTab™ ST-AUTO Kjeldahl Tablets, Potassium sulfate, 99.997% (metals basis), D01726, Potassium sulfate, Trace metals grade 99.95%, Q193054, SUPREP BOWEL PREP KIT COMPONENT Potassium sulfate, Potassium sulfate COMPONENT OF SUPREP BOWEL PREP KIT

Potassium sulfate can be described as an inorganic chemical compound having the chemical formula K2SO4.
Potassium sulfate can also be referred to as either dipotassium sulfate or Sulfuric acid dipotassium salt.

Potassium sulfate occurs naturally in salt lakes and volcanic lava.
Potassium sulfate appearance is as a colourless white crystalline powder or simply crystals.

Potassium sulfate is purely odourless and has a hard, saline-like and bitter taste.
Potassium sulfate dissolves in water, but Potassium sulfate is insoluble in ethanol. 

Potassium sulfate is an inorganic chemical compound.
Potassium sulfate is also known as Sulfuric acid dipotassium salt or diPotassium sulfate.

Potassium sulfate occurs naturally in volcanic lava and salt lakes.
Potassium sulfate appears as a colourless to white crystalline powder or crystals.

Potassium sulfate is odourless and has a bitter, hard and saline-like taste.
Potassium sulfate dissolves in water but insoluble in ethanol.

Potassium sulfate with chemical formula K2SO4.
Potassium sulfate is a water-insoluble white crystalline potassium salt.
Potassium sulfate contains 50-53% potassium (K2O) and average sulfur content of 16-20%.

Potassium sulfate also carries sulfur, which is the necessary nutrient for the plants.
Sulfur deficiency is used as a source of potassium and sulfur in cases.

Potassium sulfate is not to be confused with calcium compounds.
Potassium sulfate is composed of acid salt and alkaline salt after 17th century and Potassium sulfate has survived until today.

Potassium sulfate is obtained from brine from the Salar de Atacama and is used in the manufacture of drywall in the construction industry.

Potassium sulfate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 000 to < 10 000 000 tonnes per annum.
Potassium sulfate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Potassium sulfate contains potassium (K) and sulfur (S) – two of the essential nutrients that plants require to achieve optimum growth and reach their maximum potential.

Potassium fertilizer is commonly added to improve the yield and quality of plants growing in soils that are lacking an adequate supply of this essential nutrient.
Most fertilizer K comes from ancient salt deposits located throughout the world.
The word “potash” is a general term that most frequently refers to potassium chloride (KCl), but Potassium sulfate also applies to all other K-containing fertilizers, such as Potassium sulfate (Potassium sulfate, commonly referred to as sulfate of potash, or SOP).

Potassium sulfate can be used as a dietary ingredient and as a nutrient.
Potassium works with sodium to normalize heart rhythms and to regulate the body’s waste balance.
Potassium sulfate also preserves proper alkalinity of body fluids and assists in reducing high blood pressure.

Potassium sulfate is a moderately water and acid soluble Potassium source for uses compatible with sulfates.
Sulfate compounds are salts or esters of sulfuric acid formed by replacing one or both of the hydrogens with a metal.

Most metal sulfate compounds are readily soluble in water for uses such as water treatment, unlike fluorides and oxides which tend to be insoluble.
Organometallic forms are soluble in organic solutions and sometimes in both aqueous and organic solutions.

Metallic ions can also be dispersed utilizing suspended or coated nanoparticles and deposited utilizing sputtering targets and evaporation materials for uses such as solar cells and fuel cells.
Potassium sulfate is generally immediately available in most volumes.
High purity, submicron and nanopowder forms may be considered.

Potassium sulfate is an important nutrient for plants.
Potassium sulfate fertilizer also contains 18% sulfur in sulfate form.

Sulfur is an important nutrient, just like nitrogen, phosphorus and potassium, and is found in the structure of proteins in plants.
Potassium sulfate has benefits against plants.

Potassium deficiency is mostly seen in irrigated agriculture and rainy regions.
Potassium sulfate fertilizer should be given to sandy soils that are poor in organic matter.

Potassium sulfate is mostly used in potatoes, tobacco, vegetables, fruits, citrus fruits, legumes, corn, cotton, sugar beet and greenhouses.
If Potassium sulfate is not given in sufficient amount, yellow or reddish brown spots can be seen on the parts of the green leaves of the plants.

Potassium balances the acid-sugar ratio in the fruit, affects the coloring, increases the taste and odor, and minimizes the fruit drop problem.
Potassium sulfate provides increased endurance against frost and cold.

Applications of Potassium sulfate:
Potassium sulfate is used in gypsum cements, to make alum and glass, as a food additive, in fertilizers, as an accelerator in wallboard, as an expansion control agent for dental materials, as a medical and veterinary cathartic, and as a veterinary sulfate source.

Other Applications:
Agricultural chemicals (non-pesticidal)
Abrasives
Planting agents
Surface treating agents

Uses of Potassium sulfate:
The dominant use of the Potassium sulfate compound can be given as a fertilizer.
Potassium sulfate does not comprise chloride, which can result in harmful to a few of the crops.

Potassium sulfate can be preferred for these crops, which include some fruits, vegetables, and tobacco.
Crops with less sensitivity can still require Potassium sulfate for optimal growth if the respective soil accumulates chloride from irrigation water.

The crude salt can also be used occasionally in glass manufacturing.
Potassium sulfate can be used as a flash reducer in artillery propellant charges.

Potassium sulfate also reduces flareback, muzzle flash, and blast overpressure.
Sometimes, Potassium sulfate can be used as an alternative blast media same as the soda in soda blasting because Potassium sulfate is harder and similarly water-soluble.
Potassium sulfate is also used in pyrotechnics in combination with potassium nitrate to further generate a purple flame.

Potassium sulfate is dominantly used as a fertilizer for crops which include tobacco, some vegetables, and fruits.
Potassium sulfate is used as a salt substitute.

Potassium sulfate is used in artillery propellant charges as a flash reducer.
Potassium sulfate is used in soda blasting.

Potassium sulfate is used as a supplement for animal feeds.
Potassium sulfate is used in the production of lubricants and dyes.

Potassium sulfate is used in the manufacturing of ceramics and glass.
Potassium sulfate is used in the production of gypsum boards.

Potassium sulfate is used to synthesize potassium aluminium sulfate.
Potassium sulfate is used to produce gypsum cement.
Potassium sulfate is used in explosives as a flash suppressant

The dominant use of Potassium sulfate is as a fertilizer.
Potassium sulfate does not contain chloride, which can be harmful to some crops.

Potassium sulfate is preferred for these crops, which include tobacco and some fruits and vegetables.
Crops that are less sensitive may still require Potassium sulfate for optimal growth if the soil accumulates chloride from irrigation water.

The crude salt is also used occasionally in the manufacture of glass.
Potassium sulfate is also used as a flash reducer in artillery propellant charges.

Potassium sulfate reduces muzzle flash, flareback and blast overpressure.
Potassium sulfate is sometimes used as an alternative blast media similar to soda in soda blasting as Potassium sulfate is harder and similarly water-soluble.

Potassium sulfate can also be used in pyrotechnics in combination with potassium nitrate to generate a purple flame.
A 5% solution of Potassium sulfate was used in the beginning of the 20th century as a topical mosquito repellent.

Widespread uses by professional workers:
Potassium sulfate is used in the following products: fertilisers, plant protection products, washing & cleaning products and laboratory chemicals.
Potassium sulfate is used in the following areas: agriculture, forestry and fishing and formulation of mixtures and/or re-packaging.
Other release to the environment of Potassium sulfate is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

Uses at industrial sites:
Potassium sulfate is used in the following products: pH regulators and water treatment products, textile treatment products and dyes, leather treatment products and paper chemicals and dyes.
Potassium sulfate has an industrial use resulting in manufacture of another substance (use of intermediates).

Potassium sulfate is used in the following areas: formulation of mixtures and/or re-packaging, mining and health services.
Potassium sulfate is used for the manufacture of: chemicals and mineral products (e.g. plasters, cement).
Release to the environment of Potassium sulfate can occur from industrial use: in the production of articles, in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and industrial abrasion processing with high release rate (e.g. sanding operations or paint stripping by shot-blasting).

Industry Uses:
Agricultural chemicals (non-pesticidal)
Catalyst
Cleaning agent
Lubricating agent
Processing aids, not otherwise listed
Propellants and blowing agents
Soil amendments (fertilizers)

Consumer Uses:
Potassium sulfate is used in the following products: fertilisers and plant protection products.
Other release to the environment of Potassium sulfate is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).

Other Consumer Uses:
Agricultural chemicals (non-pesticidal)
Not Known or Reasonably Ascertainable
Soil amendments (fertilizers)

Agricultural Use:
Potassium is needed to complete many essential functions in plants, such as activating enzyme reactions, synthesizing proteins, forming starch and sugars, and regulating water flow in cells and leaves.
Often, concentrations of K in soil are too low to support healthy plant growth.

Potassium sulfate is an excellent source of K nutrition for plants.
The K portion of the Potassium sulfate is no different from other common potash fertilizers.

However, Potassium sulfate also supplies a valuable source of S, which protein synthesis and enzyme function require.
Like K, S can also be too deficient for adequate plant growth.

Further, Cl- additions should be avoided in certain soils and crops.
In such cases, Potassium sulfate makes a very suitable K source.

Potassium sulfate is only one-third as soluble as KCl, so Potassium sulfate’s not as commonly dissolved for addition through irrigation water unless there’s a need for additional S.

Several particle sizes are commonly available.
Manufacturers produce fine particles (smaller than 0.015 mm) to make solutions for irrigation or foliar sprays, since they dissolve more rapidly.
And growers find foliar spraying of Potassium sulfate a convenient way to apply additional K and S to plants, supplementing the nutrients taken up from the soil.

However, leaf damage can occur if the concentration is too high.

Management Practices:
Growers frequently use Potassium sulfate for crops where additional Cl — from more common KCl fertilizer — is undesirable.
The partial salt index of Potassium sulfate is lower than in some other common K fertilizers, so less total salinity is added per unit of K.

The salt measurement (EC) from a Potassium sulfate solution is less than a third of a similar concentration of a KCl solution (10 millimoles per liter).
Where high rates of Potassium sulfate are needed, agronomists generally recommend applying Potassium sulfate in multiple doses.
This helps avoid surplus K accumulation by the plant and also minimizes any potential salt damage.

Industrial Processes with risk of exposure:
Cement Producing
Glass Manufacturing

Usage Areas of Potassium sulfate:
Potassium sulfate helps the plant to withstand drought, cold, heat, and disease and pests.
Potassium sulfate enables plants to use water economically.

Potassium sulfate is used in potatoes, tobacco, vegetables and fruits and improves their quality.
Potassium sulfate is beneficial to use Potassium sulfate in oily plants such as olive, sunflower, canola, peanut and soybean.

In addition, by increasing the quality of straw in cereals, Potassium sulfate prevents crop lying, which causes yield losses.
Potassium sulfate can be used in all kinds of agricultural production.

Product Types:

Sulphate of Potash (SOP) is recommended for chlorid non tolerant crops:
Sunflowers
Grape vines
Stone fruits
Blackcurrants
Seed potatoes
Potatoes for human consumption
Tomatoes
Radish
Kohirabi
Peas
Spinach
Carrots
Leek
Horse-radish
Chicory
Pineapple
Cucmber
Kiwifruit
Cofee
Tea
Starch potatoes for processing
Tobacco
Redcurrants
Gooseberry
Raspberry
Strawberry
Blackberry
Blueberry
Mango
Citrus
Pepper
Chilli
Avocado
Cashew
Almond
Peach
Cocoa
Hops
Pomes and stone
Fruits (especialy cherries)
Bush beans
Broad beans
Cucumber
Melon
Onion
Letucce
Early vegetables
All crops under glass
Conifers
Flowers and ornaments as well as seedings and transplants of most plants

Benefits of Potassium sulfate:
Potassium sulfate is the most common potash fertilizer, serving as an excellent source of potassium and chloride, Potassium sulfate is not appropriate in all settings.
As many are discovering, SOP not only improves yield and crop quality, but Potassium sulfate also presents a number of advantages:

Reduced Chlorides:
Chloride makes up a significant component of MOP.
While this is preferable for some crops, Potassium sulfate can be damaging to others that are sensitive to chlorides, such as some fruits, vegetables, and nuts.
Many chloride-sensitive crops fall into the high-value category, so optimizing quality and yield are especially critical.

Additionally, if MOP is added to soils already rich in chlorides, toxicity can occur.
When working with chloride-sensitive crops or chloride-rich soils, SOP provides an optimal solution, as Potassium sulfate is substantially lower in chlorides.

Added Sulfur:
In addition to potassium, Potassium sulfate also provides plant-available sulfur.
Sulfur deficiencies have become increasingly common in recent years, making products that include the secondary nutrient increasingly desirable.

Lower Salinity:
Potassium sulfate has a lower salt index than most potash fertilizers, making Potassium sulfate the preferred choice when soil salinity is a concern.

Action Mechanism of Potassium sulfate:
Potassium is the major cation (positive ion) inside animal cells, while sodium is the major cation outside animal cells.
The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential.

The balance between potassium and sodium is maintained by ion pumps in the cell membrane.
The cell membrane potential created by potassium and sodium ions allows the cell generate an action potential—a "spike" of electrical discharge.

The ability of cells to produce electrical discharge is critical for body functions such as neurotransmission, muscle contraction, and heart function.
Potassium is also an essential mineral needed to regulate water balance, blood pressure and levels of acidity.

Structure and Properties of Potassium sulfate:
Two crystalline forms are known.
Orthorhombic β-K2SO4 is the common form, but Potassium sulfate converts to α-K2SO4 above 583 °C.
These structures are complex, although the sulfate adopts the typical tetrahedral geometry.

Potassium sulfate does not form a hydrate, unlike sodium sulfate.
The salt crystallizes as double six-sided pyramids, classified as rhombic.

They are transparent, very hard and have a bitter, salty taste.
The salt is soluble in water, but insoluble in solutions of potassium hydroxide, or in absolute ethanol.

Production of Potassium sulfate:
Approximately 1.5 million tons were produced in 1985, typically by the reaction of potassium chloride with sulfuric acid, analogous to the Mannheim process for producing sodium sulfate.

The process involves intermediate formation of potassium bisulfate, an exothermic reaction that occurs at room temperature:
KCl + H2SO4 → HCl + KHSO4

The second step of the process is endothermic, requiring energy input:
KCl + KHSO4 → HCl + K2SO4

Potassium is a relatively abundant element in the Earth’s crust, and production of potash fertilizer occurs in every inhabited continent.
However, Potassium sulfate is rarely found in a pure form in nature.
Instead Potassium sulfate is naturally mixed with salts containing magnesium, sodium and chloride (Mg, Na and Cl, respectively).

These minerals require additional processing to separate their components.
Historically, Potassium sulfate was made by reacting KCl with sulfuric acid.

However, researchers later discovered that they could manipulate a number of earth minerals to produce Potassium sulfate, now the most common method of production.
For example, natural K-containing minerals (such as kainite and schoenite) are mined and carefully rinsed with water and salt solutions to remove byproducts and produce Potassium sulfate.
The mining industry uses a similar process to harvest Potassium sulfate from the Great Salt Lake in Utah and from underground mineral deposits.

In New Mexico, Potassium sulfate is separated from langbeinite minerals by reacting Potassium sulfate with a solution of KCl, which removes the byproducts (such as Mg) and leaves Potassium sulfate.
Similar processing techniques are used in many parts of the world, depending on the raw materials accessible.

The steps followed to obtain Potassium sulfate are as follows:
Crushing the mineral langbeinite
Washing it
Extracting the mineral
Separating

Potassium sulfate is then treated with an aqueous solution of potassium chloride to separate the 2 parts of the double salt from each other.

Potassium sulfate compound can also be produced synthetically.
This is possible by treating potassium chloride with raw sulfuric acid.

Manufacturing Methods of Potassium sulfate:
Reaction of potassium chloride with langbeinite ore, schoenite obtained from kainite ore, or sodium sulfate (glaserite is an isolated intermediate); reaction of potassium chloride with sulfuric acid or sulfur dioxide, water and oxygen; recovery from sugar wastes

By treatment of potassium chloride either with sulfuric acid or with sulfur dioxide, air, & water (hargreaves process).
By fractional crystallization of natural sulfate ore; from salt lake brines.

The potassium salt of sulfuric acid.
First potash salt produced commercially in us from anything other than wood ashes.

Potassium sulfate was produced from alunite.
Sulfate has also been made from cement mill dust, langbeinite, & from muriate by treatment with sodium or magnesium sulfate or with sulfuric acid.

General Manufacturing Information of Potassium sulfate:

Industry Processing Sectors:
Agriculture, Forestry, Fishing and Hunting
All Other Basic Inorganic Chemical Manufacturing
All Other Basic Organic Chemical Manufacturing
All Other Chemical Product and Preparation Manufacturing
Explosives Manufacturing
Fabricated Metal Product Manufacturing
Miscellaneous Manufacturing
Not Known or Reasonably Ascertainable
Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing
Petroleum Lubricating Oil and Grease Manufacturing
Pharmaceutical and Medicine Manufacturing

Natural Resources of Potassium sulfate:
The mineral form of Potassium sulfate, arcanite, is relatively rare.
Natural resources of Potassium sulfate are minerals abundant in the Stassfurt salt.
These are cocrystallizations of Potassium sulfate and sulfates of magnesium, calcium, and sodium.

Relevant minerals are:
Kainite, KMg(SO4)·Cl·3H2O
Schönite (now known as picromerite), K2SO4·MgSO4·6H2O
Leonite, K2SO4·MgSO4·4H2O
Langbeinite, K2Mg2(SO4)3
Aphthitalite (previously known as glaserite), K3Na(SO4)2
Polyhalite, K2SO4·MgSO4·2CaSO4·2H2O

The Potassium sulfate can be separated from some of these minerals, like kainite, because the corresponding salt is less soluble in water.
Kieserite, MgSO4·H2O, can be combined with a solution of potassium chloride to produce Potassium sulfate.

History of Potassium sulfate:
Potassium sulfate has been known since early in the 14th century.
Potassium sulfate was studied by Glauber, Boyle, and Tachenius.

In the 17th century, Potassium sulfate was named arcanuni or sal duplicatum, as Potassium sulfate was a combination of an acid salt with an alkaline salt.
Potassium sulfate was also known as vitriolic tartar and Glaser's salt or sal polychrestum Glaseri after the pharmaceutical chemist Christopher Glaser who prepared Potassium sulfate and used medicinally.

Known as arcanum duplicatum ("double secret") or panacea duplicata in pre-modern medicine, Potassium sulfate was prepared from the residue (caput mortuum) left over from the production of aqua fortis (nitric acid, HNO3) from nitre (potassium nitrate, KNO3) and oil of vitriol (sulphuric acid, H2SO4) via Glauber's process:
2 KNO3 + H2SO4 → 2 HNO3 + K2SO4

The residue was dissolved in hot water, filtered, and evaporated to a cuticle.
Potassium sulfate was then left to crystallise.
Potassium sulfate was used as a diuretic and sudorific.

According to Chambers's Cyclopedia, the recipe was purchased for five hundred thalers by Charles Frederick, Duke of Holstein-Gottorp.
Schroder, the duke's physician, wrote wonders of Potassium sulfate great uses in hypochondriacal cases, continued and intermitting fevers, stone, scurvy, and more.

Reactions of Potassium sulfate:

Acidification:
Potassium hydrogen sulfate (also known as potassium bisulfate), KHSO4, is readily produced by reacting K2SO4 with sulfuric acid.
Potassium sulfate forms rhombic pyramids, which melt at 197 °C (387 °F).

Potassium sulfate dissolves in three parts of water at 0 °C (32 °F).
The solution behaves much as if Potassium sulfate two congeners, K2SO4 and H2SO4, were present side by side of each other uncombined; an excess of ethanol the precipitates normal sulfate (with little bisulfate) with excess acid remaining.

The behavior of the fused dry salt is similar when heated to several hundred degrees; Potassium sulfate acts on silicates, titanates, etc., the same way as sulfuric acid that is heated beyond Potassium sulfate natural boiling point does.
Hence Potassium sulfate is frequently used in analytical chemistry as a disintegrating agent.

Identifiers of Potassium sulfate:
CAS Number: 7778-80-5
ChEBI: CHEBI:32036
ChEMBL: ChEMBL2021424
ChemSpider: 22915
ECHA InfoCard: 100.029.013
EC Number: 231-915-5
E number: E515(i) (acidity regulators, ...)
KEGG: D01726 check
PubChem CID: 24507
RTECS number: TT5900000
UNII: 1K573LC5TV
CompTox Dashboard (EPA): DTXSID6029701
InChI: InChI=1S/2K.H2O4S/c;;1-5(2,3)4/h;;(H2,1,2,3,4)/q2*+1;/p-2
Key: OTYBMLCTZGSZBG-UHFFFAOYSA-L check
InChI=1/2K.H2O4S/c;;1-5(2,3)4/h;;(H2,1,2,3,4)/q2*+1;/p-2
Key: OTYBMLCTZGSZBG-NUQVWONBAU
SMILES: [K+].[K+].[O-]S([O-])(=O)=O

CAS number: 7778-80-5
EC number: 231-915-5
Grade: ACS,ISO,Reag. Ph Eur
Hill Formula: K₂O₄S
Chemical formula: K₂SO₄
Molar Mass: 174.27 g/mol
HS Code: 3105 10 00
Quality Level: MQ300

Synonyms: Potassium sulfate
Linear Formula: K2SO4
CAS Number: 7778-80-5
Molecular Weight: 174.26

EC / List no.: 231-915-5
CAS no.: 7778-80-5
Mol. formula: K2O4S

Linear Formula: K2SO4
MDL Number: MFCD00011388
EC No.: 231-915-5
Beilstein/Reaxys No.: N/A
Pubchem CID: 24507
IUPAC Name: DiPotassium sulfate
SMILES: [K+].[K+].[O-]S([O-])(=O)=O
InchI Identifier: InChI=1S/2K.H2O4S/c;;1-5(2,3)4/h;;(H2,1,2,3,4)/q2*+1;/p-2
InchI Key: OTYBMLCTZGSZBG-UHFFFAOYSA-L

CAS: 7778-80-5
Molecular Formula: K2O4S
Molecular Weight (g/mol): 174.25
MDL Number: MFCD00011388
InChI Key: OTYBMLCTZGSZBG-UHFFFAOYSA-L
PubChem CID: 24507
ChEBI: CHEBI:32036
IUPAC Name: diPotassium sulfate
SMILES: [K+].[K+].[O-]S([O-])(=O)=O

Properties of Potassium sulfate:
Chemical formula: K2SO4
Molar mass: 174.259 g/mol
Appearance: White solid
Odor: odorless
Density: 2.66 g/cm3
Melting point: 1,069 °C (1,956 °F; 1,342 K)
Boiling point: 1,689 °C (3,072 °F; 1,962 K)
Solubility in water: 111 g/L (20 °C)
120 g/L (25 °C)
240 g/L (100 °C)
Solubility product (Ksp): 1.32 (120 g/L)
Solubility: slightly soluble in glycerol
insoluble in acetone, alcohol, CS2
Magnetic susceptibility (χ): −67.0·10−6 cm3/mol
Refractive index (nD): 1.495

Boiling point: 1689 °C (1013 hPa)
Density: 2.662 g/cm3
Melting Point: 1067 °C
pH value: 7 (H₂O, 25 °C)
Bulk density: 800 kg/m3
Solubility: 111 g/l

CAS number: 7778-80-5
RTECS: TT5900000
Chemical Formula: K2SO4
Melting Point: 1069 ° C
Boiling Point: 1689 ° C
Appearance: Crystal structure (Orthorhombic)
Solubility: 111 g / L (20 ° C) -120 g / L (25 ° C) -240 g / L (100 ° C)
Density: 2.66 g / cm3

Compound Formula: K2O4S
Molecular Weight: 174.27
Appearance: White Powder
Melting Point: 1,069° C (1,956° F)
Boiling Point: 1,689° C (3,072° F)
Density: 2.66 g/cm3
Solubility in H2O: N/A
Exact Mass: 173.879 g/mol
Monoisotopic Mass: 173.879135 Da

Molecular Weight: 174.26
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0
Exact Mass: 173.87914262
Monoisotopic Mass: 173.87914262
Topological Polar Surface Area: 88.6 Ų
Heavy Atom Count: 7
Complexity: 62.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes

Specifications of Potassium sulfate:
Assay (alkalimetric): ≥ 99.0 %
Insoluble matter: ≤ 0.01 %
pH-value (5 %; water, 25 °C): 5.5 - 7.5
Chloride (Cl): ≤ 0.0005 %
Total nitrogen (N): ≤ 0.0005 %
Heavy metals (as Pb): ≤ 0.0005 %
As (Arsenic): ≤ 0.0002 %
Ca (Calcium): ≤ 0.005 %
Fe (Iron): ≤ 0.0005 %
Mg (Magnesium): ≤ 0.002 %
Na (Sodium): ≤ 0.02 %

Boiling Point: 1689°C
Melting Point: 1,067°C
Color: White
pH: 6 to 8
Physical Form: Solid
Quantity: 500 g
Assay Percent Range: ≥99 %
Formula Weight: 174.26
Percent Purity: ≥99%
Grade: Certified ACS
Identification: Pass Test
Packaging: Poly Bottle
Chemical Name or Material: Potassium sulfate

Related compounds of Potassium sulfate:
Potassium hydrogen sulfate
Potassium sulfite
Potassium bisulfite
Potassium persulfate

Other anions:
Potassium selenate
Potassium tellurate

Other cations:
Lithium sulfate
Sodium sulfate
Rubidium sulfate
Caesium sulfate

Names of Potassium sulfate:

Regulatory process names:
Potassium sulfate
Potassium sulfate
Potassium sulfate

CAS name:
Sulfuric acid potassium salt (1:2)

IUPAC names:
DiPotassium sulfate
dipottassium sulfate
K2SO4
Kaliumsulfat
not available
Potasio Sulfato
Potassium sulfate
C&L Inventory, Registration dossier
Potassium sulfate
Potassium sulfate (KCKK)
Potassium sulfate (KHSO4<1%)
Potassium sulfate (VMU)
POTASSIUM SULPHATE
Potassium Sulphate
Potassium SulphateSulphate of Potash
pottasium sulfate
Sels de potasse
SOP
Sulfuric acid dipotassium salt
Sulphate of Potash

Trade names:
ABS-P69
Acid Potassium sulfate
Arcanite
DiPotassium sulfate
diPotassium sulfate
Dipotassium sulphate
Extraits de vinasses
GSOP
HORTISUL
K2SO4
KALISOP
Kalium sulphuricum
Registration dossier
Kaliumsulfat
MagPlon NPK 5-9-18
MagPlon NPK z borem 5-9-23 + 0,1
MagPlon PK 11-24
Monopotassium hydrogen sulfate
MonoPotassium sulfate
Multi-SOP
Multi-SOP 0-0-51+42.5SO3
potash of sulfur
Potassium acid sulfate
Potassium bisulfate
Potassium bisulphate
Potassium hydrogen sulfate
Potassium hydrogensulphate
Potassium hydrosulfate (KHSO4)
Potassium sulfate
Potassium sulfate
Potassium sulfate soluble grade
Potassium Sulphate
Potassium sulphate
Potassium sulphate (technical grade)
Sels de potassium
soluSOP
SOP
SOP-3 MC
Sulfate of potash
Sulfato de potasa
Sulfato de potasio
Sulfuric acid dipotassium salt
Sulfuric acid potassium salt
sulfuric acid, potassium salt
Sulphate of Potash
Sulphate of potash
sulphate of potash
®. SOP

Other names:
Potassium sulfate
potassium sulphate
Sulfuric acid potassium salt (1:2)

Other identifier:
7778-80-5
POTASSIUM THIOGLYCOLATE
POTASSIUM THIOGLYCOLATE, N° CAS : 34452-51-2, Origine(s) : Synthétique, Nom INCI : POTASSIUM THIOGLYCOLATE, Nom chimique : Potassium mercaptoacetate, N° EINECS/ELINCS :252-038-4. Ses fonctions (INCI), Dépilatoire : Enlève les poils indésirables. Agent bouclant ou lissant (coiffant) : Modifie la structure chimique des cheveux, pour les coiffer dans le style requis
POTASSIUM TRIPOLYPHOSPHATE
POTASSIUM TRIPOLYPHOSPHATE Potassium Tripolyphosphate Solution Ca. is an odorless, colorless liquid. Potassium tripolyphosphate(KTPP) is mainly used in metal surface treatment, macroelement water soluble fertilizer, high complexation ability of metal ions. Pyrophosphate is able to form a stable complex with Ca2+ and Mg2+ in water, which can soften hard water, improved washability, removed dirt, and formed a protective layer on the surface of metal to enhance corrosion resistance. Widely used in industrial parts cleaning and metal pretreatment industry. Potassium tripolyphosphate(KTPP) solution is clarified without impurities and sediment characteristics, excellent stability, and no hydrolysis for 2 years. Reachthe international first-class standard. Potassium Tripolyphosphate solution (K5P3O10) is TongVo's hot sale products, which is used as a builder for soaps, detergents and especially liquid cleaning formulations. Potassium Tripolyphosphate solution Title: Potassium Tripolyphosphate solution Synonyms: pentapotassium triphosphate; potassium triphosphate; KTPP, Potassium Tripolyphosphate Formula: K5P3O10, Molecular: 301.03 CAS #: 13845-36-8, EC #: 237-574-9 Standard(s) of Potassium Tripolyphosphate: FCC V, Q/5749-2008 Grade of Potassium Tripolyphosphate: Technical grade, Low iron Potassium Tripolyphosphate solution Specifications ITEMS Low iron Technical grade of Potassium Tripolyphosphate Appearance of Potassium Tripolyphosphate Solid content of Potassium Tripolyphosphate Density of Potassium Tripolyphosphate g/ml Properties of Potassium tripolyphosphate Aqueous solution of Potassium tripolyphosphate is colorless clear liquid, relative density 1.55-1.6 g/cm3, It can chelate with alkaline metals ions or heavy metal ions Applications of Potassium Tripolyphosphate Potassium tripolyphosphate(KTPP) is mainly used in metal surface treatment, macroelement water soluble fertilizer, high complexation ability of metal ions. Potassium Tripolyphosphate is able to form a stable complex with Ca2+ and Mg2+ in water, which can soften hard water, improved washability, removed dirt, and formed a protective layer on the surface of metal to enhance corrosion resistance. Potassium Tripolyphosphate is Widely used in industrial parts cleaning and metal pretreatment industry. Potassium Tripolyphosphate(KTPP) solution is clarified without impurities and sediment characteristics, excellent stability, and no hydrolysis for 2 years. Reachthe international first-class standard. Storage & handling of Potassium Tripolyphosphate I Packed in 1200KG/IBC drum. Keep Potassium Tripolyphosphate in cool dry place. Air transportation: arranged as ordinary goods. Harzards Identification & Classifications: N/A Shelf life of Potassium Tripolyphosphate 12 months. DOCUMENTS MSDS / SDS (Anglais) Potassium Tripolyphosphate Solution Ca. (Anglais) Product description of Potassium Tripolyphosphate Molecular weight: 448 Chemical formula K5P3O10 Appearance clear liquid Application of Potassium Tripolyphosphate Potassium Tripolyphosphate is used in various applications. Some examples of applications of Potassium Tripolyphosphate are listed below. Used as/in: Treatment of metals Liquid cleaning agents Molecular Formula of Potassium Tripolyphosphate: K5O1P3 Molecular Weight of Potassium Tripolyphosphate: 448.403 g/mol Potassium Tripolyphosphate(KTPP) is mainly used in metal surface treatment, macroelement water soluble fertilizer, high complexation ability of metal ions. Pyrophosphate is able to form a stable complex with Ca2+ and Mg2+ in water, which can soften hard water, improved washability, removed dirt, and formed a protective layer on the surface of metal to enhance corrosion resistance. Widely used in industrial parts cleaning and metal pretreatment industry. Potassium tripolyphosphate(KTPP) solution is clarified without impurities and sediment characteristics, excellent stability, and no hydrolysis for 2 years. Reachthe international first-class standard. Potassium Tripolyphosphate solution (K5P3O10) is TongVo's hot sale products, which is used as a builder for soaps, detergents and especially liquid cleaning formulations. Sodium tripolyphosphate (STP, sometimes STPP or sodium triphosphate or TPP) is an inorganic compound with formula Na5P3O10. Potassium Tripolyphosphate is the sodium salt of the polyphosphate penta-anion, which is the conjugate base of triPhosphoric Acid.Sodium tripolyphosphate is produced by heating a stoichiometric mixture of Disodium phosphate, Na2HPO4, and Monosodium Phosphate, NaH2PO4, under carefully controlled conditions. Potassium Tripolyphosphate serve the food industry as multipurpose ingredients. Potassium Tripolyphosphate is most often used as emulsifiers, stabilisers and acidity regulators - mostly in cheese, meat products and powdered drink mixes. The food industry also adds Potassium Tripolyphosphate to fortify food with potassium, or, alternatively, to reduce its sodium content. Last but least,Potassium Tripolyphosphate can also be used as a gelling agent in instant puddings and desserts. Outside of the food industry, they are employed as a multipurpose dispersing agent in the technical sector. Potassium Tripolyphosphate ability to sequestrate metal cations is applied in water softening. The uses of Sodium tripolyphosphate also include using it as a preservative. Sodium Tripolyphosphate STPP can be used to preserve foods such as red meats, poultry, and seafood, helping them to retain their tenderness and moisture. Pet food and animal feed have been known to be treated with sodium triphosphate, serving the same general purpose as it does in human food. Saturated solution of potassium phosphate has the characteristics of clarification, no impurities and sediment, excellent stability, and no hydrolysis for 1 years. Widely used in metal surface treatment, such as industrial parts cleaning and metal pretreatment industry. 1:1 of TKPP & KTPP solution (K5P3O10) is TongVo's hot sale products, which is used as a builder for detergents and especially liquid cleaning formulations. Properties of Potassium Tripolyphosphate Aqueous solution of Potassium Tripolyphosphate is colorless clear liquid, relative density 1.55-1.6 g/cm3, Potassium Tripolyphosphate can chelate with alkaline metals ions or heavy metal ions Applications of Potassium Tripolyphosphate Potassium tripolyphosphate(KTPP) is mainly used in metal surface treatment, macroelement water soluble fertilizer, high complexation ability of metal ions. Pyrophosphate is able to form a stable complex with Ca2+ and Mg2+ in water, which can soften hard water, improved washability, removed dirt, and formed a protective layer on the surface of metal to enhance corrosion resistance. Widely used in industrial parts cleaning and metal pretreatment industry. Potassium tripolyphosphate(KTPP) solution is clarified without impurities and sediment characteristics, excellent stability, and no hydrolysis for 2 years. Reachthe international first-class standard. Storage & handling of Potassium Tripolyphosphate Packed in 1200KG/IBC drum. Keep in cool dry place. Air transportation of Potassium Tripolyphosphate: arranged as ordinary goods. Harzards Identification & Classifications: N/A Shelf life: 12 months. Grade: Technical grade, Low iron Specifications ASSAY (%) (Na5P3O10): 95 MIN APPEARANCE OF POTASSİUM TRİPOLYPHOSPHATE: WHITE GRANULAR P2O5 (%)OF POTASSİUM TRİPOLYPHOSPHATE : 57.0 MIN FLUORIDE OF POTASSİUM TRİPOLYPHOSPHATE (PPM): 10MAX CADMIUM OF POTASSİUM TRİPOLYPHOSPHATE(PPM): 1 MAX LEAD OF POTASSİUM TRİPOLYPHOSPHATE(PPM): 4 MAX MERCURY OF POTASSİUM TRİPOLYPHOSPHATE(PPM): 1 MAX ARSENIC OF POTASSİUM TRİPOLYPHOSPHATE(PPM): 3 MAX HEAVY MENTAL OF POTASSİUM TRİPOLYPHOSPHATE(AS PB) (PPM): 10 MAX CHLORIDES OF POTASSİUM TRİPOLYPHOSPHATE(AS CL) (%): 0.025 MAX SULPHATES OF POTASSİUM TRİPOLYPHOSPHATE(SO42-) (%): 0.4 MAX SUBSTANCES NOT DISSOLVED IN WATER (%): 0.05 MAX PH VALUE OF POTASSİUM TRİPOLYPHOSPHATE (%): 9.5 - 10.0 LOSS ON DRYING OF POTASSİUM TRİPOLYPHOSPHATE: 0.7% MAX HEXAHYDRATE OF POTASSİUM TRİPOLYPHOSPHATE: 23.5% MAX WATER-INSOLUBLE SUBSTANCES OF POTASSİUM TRİPOLYPHOSPHATE: 0.1% MAX HIGHER POLYPHOSPHATES OF POTASSİUM TRİPOLYPHOSPHATE: 1% MAX Apparence of Potassium Tripolyphosphate: Clair solution Dosage of Potassium Tripolyphosphate(K5P3O10): 50.0% min Fe of Potassium Tripolyphosphate: 0.05% maximum (ou 0.0015% maximum) Métal lourd of Potassium Tripolyphosphate ( comme Pb): 0.001% max Assay of Potassium Tripolyphosphate(K5P3O10): 50.0%min Fe of Potassium Tripolyphosphate: 0.05% max (or 0.0015% max) Heavy metal of Potassium Tripolyphosphate(as Pb): 0.001% max As of Potassium Tripolyphosphate: 0.0003% max pH of Potassium Tripolyphosphate(1%sol.): 10.5+-0.5 Comme of Potassium Tripolyphosphate: 0.0003% max PH of Potassium Tripolyphosphate (1% sol.): 10.5 +-0.5 Properties of Potassium Tripolyphosphate: Potassium tripolyphosphate (KTPP) solution is used as an alkali source and as a general sequestrant and dispersant in liquid detergent products. Potassium Tripolyphosphate is highly soluble in aqueous solutions with excellent dispersion properties. Potassium Tripolyphosphate has excellent chelating ability and can form stable chelates with Ca2+ and Mg2+ in hard water so as to soften hard water, increase cleaning ability, and remove dirt. The white precipitate formed from adding 13mL of 1% calcium nitrate solution into 100 mL of 1% potassium tripolyphosphate solution can be rapidly chelated to produce a clear solution. Potassium Tripolyphosphate (7758-29-4) is white granules. Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area. Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations. Applications: solution is suitable for use in any solution product where a solid KTPP product is dissolve during use. It can form a protective film on the surface of iron, lead, zine, and other metals so as to prevent surface corroding. P2O74- has a strong dispersion ability to disperse finely distributed solid particles so that these fine and trace materials can mix evenly. Potassium Tripolyphosphate has stable pH buffering ability and keep solution pH value unchanged for a long time. Potassium Tripolyphosphate is used as a builder for soaps, detergents and especially liquid cleaning formulations. Potassium tripolyphosphate Appearance: Clear solution Package: 320Kgs in 200L plastic drum, or 1500Kgs in IBCs. Other Information: (IUPAC): Atomic Weights of the Elements 2009 (IUPAC): Atomic Weights of the Elements 2009 (IUPAC): Periodic Table of the Elements Potential Uses: buffering agents, chelating agents Occurrence (nature, food, other):note, not found in nature Physical Properties: Appearance: white powder (est) Assay: 85.00 to 100.00 Food Chemicals Codex Listed: No Soluble in: water Prepared at the 26th JECFA (1982), published in FNP 25 (1982) and in FNP 52 (1992). Metals and arsenic specifications revised at the 61st JECFA (2003). No ADI was established, but a group MTDI of 70 mg/kg bw, expressed as phosphorus from all food sources, was established at the 26th JECFA (1982). DEFINITION: A heterogeneous mixture of potassium salts of linear condensed polyphosphoric acids of general formula Hn+2PnO3n+1 where "n" is not less than 2 Chemical names Potassium metaphosphate, potassium polymetaphosphate, potassium polyphosphate Assay: Not less than 53.5% and not more than 61.5% of P2O5 on the ignited basis DESCRIPTION: Odourless, colourless or white glassy masses, fragments, crystals or powder FUNCTIONAL USES: Emulsifier, moisture-retaining agent, sequestrant, texturizer Solubility (Vol. 4): 1 g dissolves in 100 ml of a 1 in 25 soln of sodium acetate Gel formation Finely powder about 1 g of the sample, and add it slowly to 100 ml of a 1 in 50 solution of sodium chloride while stirring vigorously. A gelatinous mass is formed. Test for potassium (Vol. 4) Mix 0.5 g of the sample with 10 ml of nitric acid and 50 ml of water, boil for about 30 min, and cool. The resulting solution is used for the test. Test for phosphate (Vol. 4) Mix 0.5 g of the sample with 10 ml of nitric acid and 50 ml of water, boil for about 30 min and cool. The resulting solution is used for the test PURITY : Loss on ignition (Vol. 4) Not more than 2 % after drying (105o, 4 h) followed by ignition at 550o for 30 min Cyclic phosphate (Vol. 4) Not more than 8.0% Fluoride Not more than 10 mg/kg. Arsenic (Vol. 4) Not more than 3 mg/kg (Method II). Lead (Vol. 4) Not more than 4 mg/kg. Determine using an atomic absorption technique appropriate to the specified level. The selection of sample size and method of sample preparation may be based on the principles of the method described in Volume 4, "Instrumental Methods." PURITY TESTS: Fluoride Place 5 g of the sample, 25 ml of water, 50 ml of perchloric acid, 5 drops of silver nitrate solution (1 in 2), and a few glass beads in a 250-ml distilling flask connected with a condenser and carrying a thermometer and capillary tube, both of which must extend into the liquid. Connect a small dropping funnel, filled with water, or a steam generator to the capillary tube. Support the flask on an asbestos mat with a hole which exposes about one-third of the flask to the flame. Distil into a 250-ml flask until the temperature reaches 135o. Add water from the funnel or introduce steam through the capillary to maintain the temperature between 135o and 140o. Continue the distillation until 225-240 ml has been collected, then dilute to 250 ml with water, and mix. Place a 50-ml aliquot of this solution in a 100-ml Nessler tube. In another similar Nessler tube place 50 ml of water as a control. Add to each tube 0.1 ml of filtered solution of sodium alizarinsulfonate (1 in 1,000) and 1 ml of freshly prepared hydroxylamine hydrochloride solution (1 in 4,000), and mix well. Add, dropwise, and with stirring, 0.05 N sodium hydroxide to the tube containing the distillate until its colour just matches that of the control, which is faintly pink. Then add to each tube exactly 1 ml of 0.1 N hydrochloric acid, and mix well. From a buret, graduated in 0.05-ml, add slowly to the tube containing the distillate enough thorium nitrate solution (1 in 4,000) so that, after mixing, the colour of the liquid just changes to a faint pink. Note the volume of the solution added, add exactly the same volume to the control, and mix. Now add to the control sodium fluoride TS (10 µg F per ml) from a buret to make the colours of the two tubes match after dilution to the same volume. Mix well, and allow all air bubbles to escape before making the final colour comparison. Check the end-point by adding 1 or 2 drops of sodium fluoride TS to the control. A distinct change in colour should take place. Note the volume of sodium fluoride added. The volume of sodium fluoride TS required for the control solution should not exceed 1.0 ml. METHOD OF ASSAY: Mix about 300 mg of the sample, accurately weighed, with 15 ml of nitric acid and 30 ml of water, boil for 30 min, and dilute with water to about 100 ml. Heat at 60o, add an excess of ammonium molybdate TS, and heat at 50o for 30 min. Filter, and wash the precipitate with dilute nitric acid (1 in 36 soln), followed by potassium nitrate solution (1 in 100 soln) until the filtrate is no longer acid to litmus. Dissolve the precipitate in 50 ml of 1 N sodium hydroxide, add phenolphthalein TS, and titrate the excess sodium hydroxide with 1 N sulfuric acid. Each ml of 1 N sodium hydroxide is equivalent to 3.086 mg of P2O5. Potassium Tripolyphosphate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards. Typical and custom packaging is available. Additional technical, research and safety (MSDS) information is available as is a Reference Calculator for converting relevant units of measurement. Potassium Tripolyphosphate Solution Ca. is an odorless, colorless liquid. Potassium tripolyphosphate(KTPP) is mainly used in metal surface treatment, macroelement water soluble fertilizer, high complexation ability of metal ions. Pyrophosphate is able to form a stable complex with Ca2+ and Mg2+ in water, which can soften hard water, improved washability, removed dirt, and formed a protective layer on the surface of metal to enhance corrosion resistance. Widely used in industrial parts cleaning and metal pretreatment industry. Potassium tripolyphosphate(KTPP) solution is clarified without impurities and sediment characteristics, excellent stability, and no hydrolysis for 2 years. Reachthe international first-class standard. Potassium Tripolyphosphate solution (K5P3O10) is TongVo's hot sale products, which is used as a builder for soaps, detergents and especially liquid cleaning formulations. Potassium Tripolyphosphate solution Title: Potassium Tripolyphosphate solution Synonyms: pentapotassium triphosphate; potassium triphosphate; KTPP, Potassium Tripolyphosphate Formula: K5P3O10, Molecular: 301.03 CAS #: 13845-36-8, EC #: 237-574-9 Standard(s) of Potassium Tripolyphosphate: FCC V, Q/5749-2008 Grade of Potassium Tripolyphosphate: Technical grade, Low iron Potassium Tripolyphosphate solution Specifications ITEMS Low iron Technical grade of Potassium Tripolyphosphate Appearance of Potassium Tripolyphosphate Solid content of Potassium Tripolyphosphate Density of Potassium Tripolyphosphate g/ml Properties of Potassium tripolyphosphate Aqueous solution of Potassium tripolyphosphate is colorless clear liquid, relative density 1.55-1.6 g/cm3, It can chelate with alkaline metals ions or heavy metal ions Applications of Potassium Tripolyphosphate Potassium tripolyphosphate(KTPP) is mainly used in metal surface treatment, macroelement water soluble fertilizer, high complexation ability of metal ions. Potassium Tripolyphosphate is able to form a stable complex with Ca2+ and Mg2+ in water, which can soften hard water, improved washability, removed dirt, and formed a protective layer on the surface of metal to enhance corrosion resistance. Potassium Tripolyphosphate is Widely used in industrial parts cleaning and metal pretreatment industry. Potassium Tripolyphosphate(KTPP) solution is clarified without impurities and sediment characteristics, excellent stability, and no hydrolysis for 2 years. Reachthe international first-class standard. Storage & handling of Potassium Tripolyphosphate I Packed in 1200KG/IBC drum. Keep Potassium Tripolyphosphate in cool dry place. Air transportation: arranged as ordinary goods. Harzards Identification & Classifications: N/A Shelf life of Potassium Tripolyphosphate 12 months. DOCUMENTS MSDS / SDS (Anglais) Potassium Tripolyphosphate Solution Ca. (Anglais) Product description of Potassium Tripolyphosphate Molecular weight: 448 Chemical formula K5P3O10 Appearance clear liquid Application of Potassium Tripolyphosphate Potassium Tripolyphosphate is used in various applications. Some examples of applications of Potassium Tripolyphosphate are listed below. Used as/in: Treatment of metals Liquid cleaning agents Molecular Formula of Potassium Tripolyphosphate: K5O1P3 Molecular Weight of Potassium Tripolyphosphate: 448.403 g/mol Potassium Tripolyphosphate(KTPP) is mainly used in metal surface treatment, macroelement water soluble fertilizer, high complexation ability of metal ions. Pyrophosphate is able to form a stable complex with Ca2+ and Mg2+ in water, which can soften hard water, improved washability, removed dirt, and formed a protective layer on the surface of metal to enhance corrosion resistance. Widely used in industrial parts cleaning and metal pretreatment industry. Potassium tripolyphosphate(KTPP) solution is clarified without impurities and sediment characteristics, excellent stability, and no hydrolysis for 2 years. Reachthe international first-class standard. Potassium Tripolyphosphate solution (K5P3O10) is TongVo's hot sale products, which is used as a builder for soaps, detergents and especially liquid cleaning formulations. Sodium tripolyphosphate (STP, sometimes STPP or sodium triphosphate or TPP) is an inorganic compound with formula Na5P3O10. Potassium Tripolyphosphate is the sodium salt of the polyphosphate penta-anion, which is the conjugate base of triPhosphoric Acid.Sodium tripolyphosphate is produced by heating a stoichiometric mixture of Disodium phosphate, Na2HPO4, and Monosodium Phosphate, NaH2PO4, under carefully controlled conditions. Potassium Tripolyphosphate serve the food industry as multipurpose ingredients. Potassium Tripolyphosphate is most often used as emulsifiers, stabilisers and acidity regulators - mostly in cheese, meat products and powdered drink mixes. The food industry also adds Potassium Tripolyphosphate to fortify food with potassium, or, alternatively, to reduce its sodium content. Last but least,Potassium Tripolyphosphate can also be used as a gelling agent in instant puddings and desserts. Outside of the food industry, they are employed as a multipurpose dispersing agent in the technical sector. Potassium Tripolyphosphate ability to sequestrate metal cations is applied in water softening. The uses of Sodium tripolyphosphate also include using it as a preservative. Sodium Tripolyphosphate STPP can be used to preserve foods such as red meats, poultry, and seafood, helping them to retain their tenderness and moisture. Pet food and animal feed have been known to be treated with sodium triphosphate, serving the same general purpose as it does in human food. Saturated solution of potassium phosphate has the characteristics of clarification, no impurities and sediment, excellent stability, and no hydrolysis for 1 years. Widely used in metal surface treatment, such as industrial parts cleaning and metal pretreatment industry. 1:1 of TKPP & KTPP solution (K5P3O10) is TongVo's hot sale products, which is used as a builder for detergents and especially liquid cleaning formulations. Properties of Potassium Tripolyphosphate Aqueous solution of Potassium Tripolyphosphate is colorless clear liquid, relative density 1.55-1.6 g/cm3, Potassium Tripolyphosphate can chelate with alkaline metals ions or heavy metal ions Applications of Potassium Tripolyphosphate Potassium tripolyphosphate(KTPP) is mainly used in metal surface treatment, macroelement water soluble fertilizer, high complexation ability of metal ions. Pyrophosphate is able to form a stable complex with Ca2+ and Mg2+ in water, which can soften hard water, improved washability, removed dirt, and formed a protective layer on the surface of metal to enhance corrosion resistance. Widely used in industrial parts cleaning and metal pretreatment industry. Potassium tripolyphosphate(KTPP) solution is clarified without impurities and sediment characteristics, excellent stability, and no hydrolysis for 2 years. Reachthe international first-class standard. Storage & handling of Potassium Tripolyphosphate Packed in 1200KG/IBC drum. Keep in cool dry place. Air transportation of Potassium Tripolyphosphate: arranged as ordinary goods. Harzards Identification & Classifications: N/A Shelf life: 12 months. Grade: Technical grade, Low iron Specifications ASSAY (%) (Na5P3O10): 95 MIN APPEARANCE OF POTASSİUM TRİPOLYPHOSPHATE: WHITE GRANULAR P2O5 (%)OF POTASSİUM TRİPOLYPHOSPHATE : 57.0 MIN FLUORIDE OF POTASSİUM TRİPOLYPHOSPHATE (PPM): 10MAX CADMIUM OF POTASSİUM TRİPOLYPHOSPHATE(PPM): 1 MAX LEAD OF POTASSİUM TRİPOLYPHOSPHATE(PPM): 4 MAX MERCURY OF POTASSİUM TRİPOLYPHOSPHATE(PPM): 1 MAX ARSENIC OF POTASSİUM TRİPOLYPHOSPHATE(PPM): 3 MAX HEAVY MENTAL OF POTASSİUM TRİPOLYPHOSPHATE(AS PB) (PPM): 10 MAX CHLORIDES OF POTASSİUM TRİPOLYPHOSPHATE(AS CL) (%): 0.025 MAX SULPHATES OF POTASSİUM TRİPOLYPHOSPHATE(SO42-) (%): 0.4 MAX SUBSTANCES NOT DISSOLVED IN WATER (%): 0.05 MAX PH VALUE OF POTASSİUM TRİPOLYPHOSPHATE (%): 9.5 - 10.0 LOSS ON DRYING OF POTASSİUM TRİPOLYPHOSPHATE: 0.7% MAX HEXAHYDRATE OF POTASSİUM TRİPOLYPHOSPHATE: 23.5% MAX WATER-INSOLUBLE SUBSTANCES OF POTASSİUM TRİPOLYPHOSPHATE: 0.1% MAX HIGHER POLYPHOSPHATES OF POTASSİUM TRİPOLYPHOSPHATE: 1% MAX Apparence of Potassium Tripolyphosphate: Clair solution Dosage of Potassium Tripolyphosphate(K5P3O10): 50.0% min Fe of Potassium Tripolyphosphate: 0.05% maximum (ou 0.0015% maximum) Métal lourd of Potassium Tripolyphosphate ( comme Pb): 0.001% max Assay of Potassium Tripolyphosphate(K5P3O10): 50.0%min Fe of Potassium Tripolyphosphate: 0.05% max (or 0.0015% max) Heavy metal of Potassium Tripolyphosphate(as Pb): 0.001% max As of Potassium Tripolyphosphate: 0.0003% max pH of Potassium Tripolyphosphate(1%sol.): 10.5+-0.5 Comme of Potassium Tripolyphosphate: 0.0003% max PH of Potassium Tripolyphosphate (1% sol.): 10.5 +-0.5 Properties of Potassium Tripolyphosphate: Potassium tripolyphosphate (KTPP) solution is used as an alkali source and as a general sequestrant and dispersant in liquid detergent products. Potassium Tripolyphosphate is highly soluble in aqueous solutions with excellent dispersion properties. Potassium Tripolyphosphate has excellent chelating ability and can form stable chelates with Ca2+ and Mg2+ in hard water so as to soften hard water, increase cleaning ability, and remove dirt. The white precipitate formed from adding 13mL of 1% calcium nitrate solution into 100 mL of 1% potassium tripolyphosphate solution can be rapidly chelated to produce a clear solution. Potassium Tripolyphosphate (7758-29-4) is white granules. Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area. Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations. Applications: solution is suitable for use in any solution product where a solid KTPP product is dissolve during use. It can form a protective film on the surface of iron, lead, zine, and other metals so as to prevent surface corroding. P2O74- has a strong dispersion ability to disperse finely distributed solid particles so that these fine and trace materials can mix evenly. Potassium Tripolyphosphate has stable pH buffering ability and keep solution pH value unchanged for a long time. Potassium Tripolyphosphate is used as a builder for soaps, detergents and especially liquid cleaning formulations. Potassium tripolyphosphate Appearance: Clear solution Package: 320Kgs in 200L plastic drum, or 1500Kgs in IBCs. Other Information: (IUPAC): Atomic Weights of the Elements 2009 (IUPAC): Atomic Weights of the Elements 2009 (IUPAC): Periodic Table of the Elements Potential Uses: buffering agents, chelating agents Occurrence (nature, food, other):note, not found in nature Physical Properties: Appearance: white powder (est) Assay: 85.00 to 100.00 Food Chemicals Codex Listed: No Soluble in: water Prepared at the 26th JECFA (1982), published in FNP 25 (1982) and in FNP 52 (1992). Metals and arsenic specifications revised at the 61st JECFA (2003). No ADI was established, but a group MTDI of 70 mg/kg bw, expressed as phosphorus from all food sources, was established at the 26th JECFA (1982). DEFINITION: A heterogeneous mixture of potassium salts of linear condensed polyphosphoric acids of general formula Hn+2PnO3n+1 where "n" is not less than 2 Chemical names Potassium metaphosphate, potassium polymetaphosphate, potassium polyphosphate Assay: Not less than 53.5% and not more than 61.5% of P2O5 on the ignited basis DESCRIPTION: Odourless, colourless or white glassy masses, fragments, crystals or powder FUNCTIONAL USES: Emulsifier, moisture-retaining agent, sequestrant, texturizer Solubility (Vol. 4): 1 g dissolves in 100 ml of a 1 in 25 soln of sodium acetate Gel formation Finely powder about 1 g of the sample, and add it slowly to 100 ml of a 1 in 50 solution of sodium chloride while stirring vigorously. A gelatinous mass is formed. Test for potassium (Vol. 4) Mix 0.5 g of the sample with 10 ml of nitric acid and 50 ml of water, boil for about 30 min, and cool. The resulting solution is used for the test. Test for phosphate (Vol. 4) Mix 0.5 g of the sample with 10 ml of nitric acid and 50 ml of water, boil for about 30 min and cool. The resulting solution is used for the test PURITY : Loss on ignition (Vol. 4) Not more than 2 % after drying (105o, 4 h) followed by ignition at 550o for 30 min Cyclic phosphate (Vol. 4) Not more than 8.0% Fluoride Not more than 10 mg/kg. Arsenic (Vol. 4) Not more than 3 mg/kg (Method II). Lead (Vol. 4) Not more than 4 mg/kg. Determine using an atomic absorption technique appropriate to the specified level. The selection of sample size and method of sample preparation may be based on the principles of the method described in Volume 4, "Instrumental Methods." PURITY TESTS: Fluoride Place 5 g of the sample, 25 ml of water, 50 ml of perchloric acid, 5 drops of silver nitrate solution (1 in 2), and a few glass beads in a 250-ml distilling flask connected with a condenser and carrying a thermometer and capillary tube, both of which must extend into the liquid. Connect a small dropping funnel, filled with water, or a steam generator to the capillary tube. Support the flask on an asbestos mat with a hole which exposes about one-third of the flask to the flame. Distil into a 250-ml flask until the temperature reaches 135o. Add water from the funnel or introduce steam through the capillary to maintain the temperature between 135o and 140o. Continue the distillation until 225-240 ml has been collected, then dilute to 250 ml with water, and mix. Place a 50-ml aliquot of this solution in a 100-ml Nessler tube. In another similar Nessler tube place 50 ml of water as a control. Add to each tube 0.1 ml of filtered solution of sodium alizarinsulfonate (1 in 1,000) and 1 ml of freshly prepared hydroxylamine hydrochloride solution (1 in 4,000), and mix well. Add, dropwise, and with stirring, 0.05 N sodium hydroxide to the tube containing the distillate until its colour just matches that of the control, which is faintly pink. Then add to each tube exactly 1 ml of 0.1 N hydrochloric acid, and mix well. From a buret, graduated in 0.05-ml, add slowly to the tube containing the distillate enough thorium nitrate solution (1 in 4,000) so that, after mixing, the colour of the liquid just changes to a faint pink. Note the volume of the solution added, add exactly the same volume to the control, and mix. Now add to the control sodium fluoride TS (10 µg F per ml) from a buret to make the colours of the two tubes match after dilution to the same volume. Mix well, and allow all air bubbles to escape before making the final colour comparison. Check the end-point by adding 1 or 2 drops of sodium fluoride TS to the control. A distinct change in colour should take place. Note the volume of sodium fluoride added. The volume of sodium fluoride TS required for the control solution should not exceed 1.0 ml. METHOD OF ASSAY: Mix about 300 mg of the sample, accurately weighed, with 15 ml of nitric acid and 30 ml of water, boil for 30 min, and dilute with water to about 100 ml. Heat at 60o, add an excess of ammonium molybdate TS, and heat at 50o for 30 min. Filter, and wash the precipitate with dilute nitric acid (1 in 36 soln), followed by potassium nitrate solution (1 in 100 soln) until the filtrate is no longer acid to litmus. Dissolve the precipitate in 50 ml of 1 N sodium hydroxide, add phenolphthalein TS, and titrate the excess sodium hydroxide with 1 N sulfuric acid. Each ml of 1 N sodium hydroxide is equivalent to 3.086 mg of P2O5. Potassium Tripolyphosphate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards. Typical and custom packaging is available. Additional technical, research and safety (MSDS) information is available as is a Reference Calculator for converting relevan
POTASSIUMTRIPOLYPHOSPHATE-GRANULE
Potassium tripolyphosphate 50%; KTPP %50; pentapotassium triphosphate %50 cas no: 13845-36-8
POTASSIUMTRIPOLYPHOSPHATE-LIQUID
Acetic acid, potassium salt; Diuretic Salt; Octan draselny CAS NO: 127-08-2
Potassium Benzoate
Benzoate of potash; Potassium salt of benzoic acid; benzoic acid, potassium salt; Potassium salt of Benzenecarboxylic acid; Potassium salt of Phenylcarboxylic acid CAS NO: 582-25-2
Potassium Bicarbonate
SYNONYMS Bromide of potassium; tripotassium tribromide; Hydrobromic Acid Potassium Salt; Bromide Salt of Potassium; CAS NO. 7758-02-3
Potassium Bromide
Potash; Salt of Tartar; Carbonic acid, Dipotassium salt; Potassium carbonate (2:1); Kaliumcarbonat; Pearl ash CAS NO:584-08-7
Potassium Carbonate
SYNONYMS Potassium muriate; Dipotassium dichloride; Potassium monochloride; potash muriate; chloropotassuril; kalcorid; kalitabs; potavescent; rekawan; chlorovescent; k-contin; peter-kal; Chlorure de potassium; SPAN-K; Super K; Cas no: 7447-40-7
Potassium Ferricyanide
Bromide of potassium; tripotassium tribromide; Hydrobromic Acid Potassium Salt; Bromide Salt of Potassium; BROMIDE BROMATE; Bromidesalt of potassium; BROMINE; BROMINE CONCENTRATE; BROMINE LIQUID; BROMINE TS; BROMINE WATER; BROMINE WATER, SATURATED; KALII BROMIDUM; KOPPESCHARR'S SOLUTION; POTASSIUM BROMIDE; POTASSIUM BROMIDE, APHA FOR HG; POTASSIUM BROMIDE SALINE; bromuredepotassium CAS NO:7758-02-3
Potassium Ferrocyanide
Potash; Salt of Tartar; Carbonic acid, Dipotassium salt; Potassium carbonate (2:1); Kaliumcarbonat; Pearl ash; cas no : 584-08-7
Potassium Fluoborate
Potash; Salt of Tartar; Carbonic acid, Dipotassium salt; Potassium carbonate (2:1); Kaliumcarbonat; Pearl ash; K2CO3; K-Gran; POTASH; PEARL ASH; Pearl dust; Sal absinthii; Kaliumcarbonat; SALT OF TARTAR; alt of wormwood; Montreal potash CAS NO:584-08-7
Potassium Fluorozirconate
Potash Chlorate; Chloric Acid, Potassium Salt; Berthollet salt; Chlorate of Potash; cas no: 3811-04-9
Potassium Formate
Monopotassium persulfate; Potassium hydrogen peroxomonosulfate; Monopotassium peroxymonosulfate; potassium monopersulfate triple salt; Potassium sulfodioxidanide; Peroxosulfic acid O-potassium salt; Potassium (hydroperoxysulfonyl)oxidanide; potassium peroxymonosulfuric acid CAS NO:10058-23-8
Potassium Hydrogen Peroxomonosulfate
Potassium hydrate; Caustic potash; Lye; potassa; Hydroxyde De Potassium; Potasse Caustique; Kaliumhydroxid; Kaliumhydroxyde; Potassa; Potassio Idrossido Di; K(OH) CAS NO:1310-58-3
Potassium Hydroxide
potassium hydroxide; Potassium hydrate; Caustic potash; Lye; potassa; Hydroxyde De Potassium; Potasse Caustique; Kaliumhydroxid; Kaliumhydroxyde; Potassa; Potassio Idrossido Di; K(OH); cas no: 1310-58-3
potassium isopentyl dithiocarbonate
potassıum lignosulfonate; Potassium Lignin Sulfonate; Lignosulfonic acid; potassium salt cas no: 37314-65-1
potassium lignosulfonate
potassium permanganate; Permanganic acid, potassium salt; C.I. 77755; Chameleon mineral; Condy's crystals; Kaliumpermanganat; Permanganate de potassium; Permanganate of potash; Permanganato potasico; Potassio (permanganato di); Potassium (permanganate de); Potassium manganate (Ⅶ) cas no: 7722-64-7
POTASSİUM OLEATE

Potassium oleate is the potassium salt of oleic acid. Oleic acid is a fatty acid that belongs to the omega-9 family and is commonly found in various vegetable oils, particularly olive oil.
When oleic acid reacts with potassium hydroxide (KOH), the resulting compound is potassium oleate.
Potassium Oleate is a potassium salt derived from oleic acid, a monounsaturated fatty acid.
Potassium oleate is formed by the reaction of oleic acid with potassium hydroxide.

CAS Number: 143-18-0
EC Number: 205-594-7



APPLICATIONS


Potassium Oleate is widely used in the production of liquid soaps, contributing to their cleansing and foaming properties.
In shampoo formulations, Potassium Oleate serves as a surfactant, aiding in the removal of dirt and oils from the hair.
Potassium oleate is a key ingredient in bath products, such as shower gels and bubble baths, providing a mild and effective cleansing experience.

Potassium Oleate finds application in the formulation of facial cleansers and body washes, offering gentle and skin-friendly cleansing.
Potassium oleate is utilized in the creation of environmentally friendly and biodegradable cleaning products.
Potassium Oleate is incorporated into industrial cleaning formulations for its emulsifying and detergent properties.
In metalworking fluids, Potassium Oleate acts as a lubricant, improving the efficiency of cutting and machining processes.

Potassium oleate is employed in the production of textile auxiliaries, contributing to the removal of impurities from fabrics.
Potassium Oleate is used in the cosmetics industry for its emulsifying capabilities in the formulation of creams and lotions.
Potassium oleate is a key ingredient in the creation of paint and coating formulations, aiding in pigment dispersion.

In pharmaceuticals, Potassium Oleate may be utilized as a stabilizing agent in certain formulations.
Potassium Oleate is incorporated into agricultural formulations for its emulsifying properties in pesticide and herbicide products.
Potassium oleate is utilized in the creation of leather and textile finishing agents, contributing to the softness and appearance of materials.
Potassium Oleate can be found in the formulation of ink and printing products, helping disperse pigments uniformly.

Potassium oleate is used in the creation of emulsions in the food industry, particularly in the formulation of certain food additives.
Potassium Oleate serves as a dispersing agent in the production of specialty chemicals and industrial products.
Potassium oleate finds application in the manufacturing of polymeric materials, contributing to their processing and stability.

Potassium Oleate may be used in the formulation of certain pharmaceutical creams and ointments.
Potassium oleate is employed in the creation of metal cleaning agents, aiding in the removal of oils and residues.
In the construction industry, Potassium Oleate is utilized in the formulation of coatings and sealants.

Potassium oleate contributes to the stability of certain cosmetic formulations, such as foundations and sunscreens.
Potassium Oleate is incorporated into cutting fluids used in machining processes to enhance lubrication.
Potassium oleate plays a role in the production of pet care products, such as shampoos and grooming solutions.

Potassium Oleate is utilized in the creation of specialty industrial products, including anti-corrosion agents.
Potassium oleate's versatile properties make it a valuable ingredient in a range of applications, from personal care to industrial processes.

Potassium Oleate is an essential component in the formulation of facial cleansers, aiding in the gentle removal of makeup and impurities.
Potassium oleate is used in the creation of bath oils and body scrubs, contributing to the overall skincare experience.
Potassium Oleate is a common ingredient in hand soaps, providing effective cleansing while maintaining skin softness.

Potassium oleate finds application in the formulation of dishwashing liquids, enhancing their grease-cutting abilities.
In the textile industry, Potassium Oleate is utilized in fabric softeners for its emollient properties.
Potassium oleate is added to certain industrial degreasers to improve their efficacy in removing oils and contaminants.

Potassium Oleate serves as a stabilizing agent in the formulation of emulsifiable concentrates in agrochemicals.
Potassium oleate is employed in the creation of hair conditioners, contributing to detangling and softening effects.

Potassium oleate finds use in the production of lubricants for metalworking processes, aiding in the reduction of friction.
Potassium Oleate is utilized in the formulation of leather cleaners and conditioners for its cleansing and softening properties.
Potassium oleate is incorporated into printing ink formulations to assist in pigment dispersion and print quality.
Potassium oleate is added to certain adhesive formulations to improve their bonding capabilities.

In the paper industry, Potassium Oleate may be used in the sizing process to enhance paper strength and quality.
Potassium oleate is utilized in the formulation of certain cosmetic creams and lotions, providing a smooth and spreadable texture.
Potassium Oleate is found in the composition of certain paint strippers, aiding in the removal of paint coatings.

Potassium oleate serves as a key ingredient in the creation of cutting oils for metalworking applications.
Potassium oleate is utilized in the formulation of anti-fogging agents for use in eyeglasses and mirrors.

Potassium Oleate finds application in the creation of rust inhibitors for metal surfaces.
Potassium oleate is employed in the formulation of certain hair dyes and coloring products.

Potassium Oleate may be used in the creation of mold release agents for plastic and rubber manufacturing.
Potassium oleate is found in certain cosmetic and skincare formulations for its emulsifying and stabilizing properties.
Potassium oleate contributes to the production of certain types of adhesives used in woodworking and construction.

Potassium Oleate is added to certain industrial cleaning agents for its ability to solubilize oils and greases.
Potassium oleate plays a role in the creation of drilling fluids for oil and gas exploration.
Potassium Oleate is utilized in the formulation of inkjet printer inks for its dispersing properties and print quality enhancement.

Potassium Oleate is employed in the formulation of rust preventatives and coatings to protect metal surfaces from corrosion.
Potassium oleate is utilized in the creation of emulsifiable concentrates for agricultural use, enhancing the dispersion of active ingredients.
Potassium Oleate finds application in the production of bath oils, contributing to the emollient and moisturizing properties.

Potassium oleate is added to certain cosmetic formulations, such as creams and lotions, to improve texture and stability.
In the textile industry, Potassium Oleate may be used in dyeing processes to aid in the even dispersion of dyes.

Potassium oleate is utilized in the manufacturing of household cleaning products, including multipurpose cleaners and degreasers.
Potassium Oleate serves as a stabilizing agent in the formulation of certain polymeric materials and coatings.
Potassium oleate is found in the composition of certain lubricating greases for industrial machinery.

Potassium oleate is added to the formulation of metal polishes to aid in the removal of tarnish and oxidation from metal surfaces.
Potassium Oleate is employed in the creation of wood preservatives for its ability to penetrate and protect against decay.

Potassium oleate finds use in the production of textile softeners, enhancing the feel and comfort of fabrics.
Potassium oleate is utilized in the creation of pet shampoos and grooming products for its mild cleansing properties.
Potassium Oleate is incorporated into certain paint formulations to improve flow and leveling characteristics.

Potassium oleate may be used in the creation of cooling and cutting fluids for metalworking processes.
Potassium Oleate serves as a dispersing agent in the formulation of pigmented coatings and paints.
Potassium oleate is added to certain pesticide formulations to improve the dispersion of active ingredients on crops.
Potassium oleate is employed in the creation of printing and lithographic inks for its ink-dispersing properties.

Potassium Oleate is utilized in the production of certain adhesive and sealant formulations.
Potassium oleate finds application in the creation of rubber processing aids, aiding in the molding and shaping of rubber products.

Potassium oleate is added to certain industrial lubricants to improve their anti-wear and friction-reducing properties.
Potassium Oleate may be used in the formulation of metal cleaners for household and industrial applications.
Potassium oleate is incorporated into certain concrete and cement admixtures to enhance workability and dispersion.

Potassium oleate finds use in the formulation of certain agrochemicals, including plant growth regulators and herbicides.
Potassium Oleate is added to the formulation of certain fire-resistant hydraulic fluids for industrial applications.
Potassium oleate serves as an emulsifying agent in the creation of emulsions used in various industries, including food and pharmaceuticals.

Potassium Oleate is utilized in the formulation of water-in-oil emulsions for use in cosmetic and pharmaceutical creams.
Potassium oleate plays a role in the creation of anti-fogging agents used in products such as eyeglasses, mirrors, and camera lenses.

Potassium Oleate is employed in the formulation of leather cleaners, aiding in the removal of dirt and stains.
Potassium oleate is added to certain adhesive formulations to improve bonding strength in woodworking and construction.
Potassium oleate contributes to the creation of emulsifiable concentrates used in the preparation of agricultural herbicides.

Potassium Oleate is found in the composition of certain sunscreen formulations, contributing to their emulsifying properties.
Potassium oleate serves as a stabilizing agent in the production of certain vaccine formulations in the pharmaceutical industry.
Potassium oleate is utilized in the creation of corrosion inhibitors for use in industrial processes and metal protection.

Potassium Oleate may be added to drilling fluids in the oil and gas industry for its emulsifying and stabilizing effects.
Potassium oleate plays a role in the formulation of mold release agents for the production of plastic and rubber goods.
Potassium oleate is incorporated into certain ink formulations to improve print quality and dispersion.

Potassium Oleate is employed in the manufacturing of environmentally friendly and biodegradable cleaning products.
Potassium oleate contributes to the formulation of metalworking fluids, enhancing lubrication and cooling during machining processes.
Potassium oleate is used in the creation of rust inhibitors for the protection of metal surfaces from oxidation.

Potassium Oleate may be found in the composition of certain air fresheners and deodorizers.
Potassium oleate is utilized in the formulation of corrosion-resistant coatings for use in marine and industrial environments.
Potassium Oleate is added to certain wax formulations to improve their texture and application properties.
Potassium oleate contributes to the creation of pigment dispersions used in the coloring of various products.

Potassium oleate plays a role in the formulation of textile auxiliaries, contributing to the finishing of fabrics.
Potassium Oleate is utilized in the production of certain metalworking additives for improved machining performance.
Potassium oleate is incorporated into cutting fluids used in metalworking processes to reduce friction and heat generation.

Potassium oleate finds use in the creation of anti-tack agents used in the rubber industry.
Potassium Oleate is employed in the formulation of inkjet printer inks for its dispersing and wetting properties.
Potassium oleate plays a role in the creation of specialty chemicals used in the production of polymers and resins.
Potassium oleate is utilized in the formulation of wax and polish products for automotive and furniture applications.



DESCRIPTION


Potassium oleate is the potassium salt of oleic acid. Oleic acid is a fatty acid that belongs to the omega-9 family and is commonly found in various vegetable oils, particularly olive oil.
When oleic acid reacts with potassium hydroxide (KOH), the resulting compound is potassium oleate.

Potassium Oleate is a potassium salt derived from oleic acid, a monounsaturated fatty acid.
Potassium oleate is formed by the reaction of oleic acid with potassium hydroxide.
Potassium oleate appears as a pale-yellow to amber-colored liquid or solid, depending on its concentration and temperature.
Potassium Oleate is known for its surfactant properties, making it useful in soap-making processes.

Potassium oleate possesses emulsifying and cleansing abilities, contributing to its applications in various cleaning and personal care products.
The chemical structure of Potassium Oleate includes a long hydrophobic tail and a hydrophilic head, typical of soap molecules.
Potassium oleate is commonly used as a potassium soap in the formulation of liquid soaps, shampoos, and bath products.

Potassium Oleate plays a crucial role in stabilizing oil-in-water emulsions, enhancing their cleansing efficacy.
In addition to its use in personal care products, Potassium Oleate is employed in industrial cleaning formulations.
Potassium oleate exhibits good solubility in water, facilitating its incorporation into aqueous-based formulations.

Potassium Oleate is often utilized in the production of environmentally friendly and biodegradable cleaning products.
Potassium oleate contributes to the formation of stable lather in soap products, enhancing their foaming and cleansing properties.

Potassium Oleate can be synthesized through the saponification of natural oils, such as olive oil or sunflower oil.
Potassium oleate is a versatile ingredient, finding applications in both liquid and solid soap formulations.
Potassium Oleate is known for its mild and gentle cleansing action on the skin and hair.

Potassium oleate is compatible with a wide range of cosmetic ingredients, making it a popular choice in personal care formulations.
Its amphiphilic nature allows it to interact with both water and oil, facilitating the removal of dirt and grease.
Potassium Oleate is employed in the formulation of metalworking fluids, aiding in the lubrication and cooling of cutting processes.
Potassium oleate's detergent properties make it effective in removing oils and stains from various surfaces.

Potassium Oleate is biodegradable, reducing its environmental impact when used in cleaning products.
Potassium oleate contributes to the stability and homogeneity of certain pharmaceutical formulations.
Potassium Oleate can act as a dispersing agent, assisting in the uniform distribution of pigments in paints and coatings.

Potassium oleate may be used in the formulation of specialty industrial products, such as anti-corrosion agents.
Potassium Oleate's soap-forming properties make it a valuable ingredient in the creation of emulsions in the food industry.
Potassium oleate is essential to handle Potassium Oleate with care, following safety guidelines and proper storage conditions to maintain its efficacy in various applications.



PROPERTIES


Chemical Formula: CH₃(CH₂)₇CH=CH(CH₂)₇COOK
Molecular Weight: Approximately 320.5 g/mol
Appearance: Depending on concentration and temperature, it can be a pale-yellow to amber-colored liquid or solid.
Odor: Generally odorless.
Solubility:
Soluble in water.
Soluble in various organic solvents.
pH: Typically alkaline.
Melting Point: Varies depending on concentration, often a semi-solid or liquid at room temperature.
Boiling Point: Decomposes before boiling.
Density: Varies depending on concentration and form (liquid or solid).
Flash Point: Not applicable, as it does not have a distinct boiling point.
Viscosity: Typically low viscosity in liquid form.
Surface Tension: Exhibits surfactant properties, reducing surface tension in aqueous solutions.
Hygroscopicity: Absorbs moisture from the air.
Emulsifying Properties: Acts as an effective emulsifying agent, aiding in the dispersion of oil in water.
Ionic Nature: Ionic (due to the presence of the potassium ion).
Biodegradability: Generally considered biodegradable under environmental conditions.
Stability: Stable under normal storage and handling conditions.
Compatibility: Compatible with a wide range of cosmetic and industrial ingredients.
Toxicity: Generally considered low toxicity, but specific safety guidelines should be followed.
Environmental Impact: Biodegradable and may be considered environmentally friendly.
Flammability: Not considered flammable.



FIRST AID


Inhalation:

Move the affected person to fresh air.
If breathing is difficult, administer artificial respiration.
Seek medical attention if respiratory distress persists.


Skin Contact:

Remove contaminated clothing and shoes.
Wash the affected area thoroughly with soap and water.
If irritation or redness occurs, seek medical attention.


Eye Contact:

Rinse eyes gently with water for at least 15 minutes, holding eyelids open.
Seek immediate medical attention if irritation, redness, or other symptoms persist.


Ingestion:

Rinse the mouth thoroughly with water.
Do not induce vomiting unless directed by medical personnel.
Seek immediate medical attention or contact a poison control center.


Note:

If Potassium Oleate is ingested, it is crucial to provide medical attention promptly.
Do not delay seeking professional medical help, and have the product's SDS or label available for the healthcare provider.


General First Aid Measures:

Personal Protection:
Use appropriate personal protective equipment (PPE) during the first aid response.

Symptom Management:
Treat symptoms based on the affected individual's condition.
For example, if irritation persists, provide soothing measures as directed by medical personnel.

Medical Attention:
Always seek professional medical attention for any exposure or ingestion of Potassium Oleate, even if symptoms seem mild.

Note for Healthcare Providers:
Provide healthcare professionals with information about the substance, including its chemical name, concentration, and any other relevant details available on the product label or SDS.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including gloves, protective clothing, and safety goggles or a face shield, to prevent skin and eye contact.

Ventilation:
Use in well-ventilated areas or under local exhaust ventilation to minimize inhalation exposure.

Avoidance of Contact:
Avoid contact with skin, eyes, and clothing. In case of contact, follow first aid measures as outlined in the SDS.

Hygiene Practices:
Wash hands thoroughly after handling Potassium Oleate.
Do not eat, drink, or smoke while working with the substance.

Equipment:
Use corrosion-resistant equipment when handling the substance.
Ensure that equipment is clean and free of contaminants before use.

Spill and Leak Response:
In the event of a spill, use appropriate absorbent materials to contain and clean up the substance.
Follow spill response procedures outlined in the SDS.

Storage Compatibility:
Store away from incompatible materials, including strong acids, strong bases, and oxidizing agents.
Keep away from open flames, heat sources, and ignition sparks.

Handling Precautions:
Avoid creating dust or aerosols during handling.
Use non-sparking tools and equipment to minimize the risk of ignition.


Storage:

Storage Area:
Store Potassium Oleate in a cool, dry, and well-ventilated area.
Keep away from direct sunlight and sources of heat.

Temperature Control:
Store at temperatures below the specified maximum storage temperature.
Check the product specifications for any temperature-sensitive considerations.

Containers:
Store in tightly sealed containers to prevent moisture absorption and contamination.
Use containers made of materials compatible with Potassium Oleate, such as high-density polyethylene (HDPE) or glass.

Segregation:
Segregate Potassium Oleate from incompatible materials as per hazard classification guidelines.

Labeling:
Ensure that storage containers are properly labeled with product information, hazard symbols, and precautionary measures.

Control of Ignition Sources:
Avoid storing near sources of open flames, sparks, or hot surfaces.

Inventory Control:
Implement a first-in, first-out (FIFO) inventory control system to use older stock first.

Secondary Containment:
Consider using secondary containment measures to contain spills and leaks in case of container failure.


Emergency Preparedness:

Emergency Procedures:
Have emergency response procedures in place, including contact information for emergency services and a designated spill response team.

Training:
Ensure that personnel are trained in emergency response procedures and are familiar with the location of emergency equipment.



SYNONYMS


Potassium cis-9-octadecenoate
Potassium 9-octadecenoate
Potassium (Z)-9-octadecenoate
Potassium (9Z)-octadec-9-enoate
Potassium Perchlorate
potassium hydroxide; Potassium hydrate; Caustic potash; Lye; potassa; Hydroxyde De Potassium; Potasse Caustique; Kaliumhydroxid; Kaliumhydroxyde; Potassa; Potassio Idrossido Di; K(OH); cas no: 1310-58-3
potassium permanganate
Permanganic acid, potassium salt; C.I. 77755; Chameleon mineral; Condy's crystals; Kaliumpermanganat; Permanganate de potassium; Permanganate of potash; Permanganato potasico; Potassio (permanganato di); Potassium (permanganate de); Potassium manganate (Ⅶ) CAS:7722-64-7
Potassium Peroxymonosulfate
Caroat; Oxone; potassium monopersulfate; MPS CAS:10058-23-8; 37222-66-5
Potassium Peroxymonosulfate (Oxone)
Caroat; Oxone; potassium monopersulfate; MPS CAS:10058-23-8; 37222-66-5
Potassium Silicofluoride
Potassium persulfate; Peroxydisulfuric acid, dipotassium salt; Dipotassium persulfate; Potassium Peroxydisulfate; Potassium peroxydisulphate; CAS NO: 7727-21-1
Potassium sodium tartrate
Sorbic acid potassium salt; Potassium 2,4-hexadienoate; 2,4-Hexadienoic aAcid potassium salt; Sorbistat; Sorbistat-K; Sorbistat-potassium; Potassium sorbate CAS NO: 590-00-1
Potassium Stannate
potassıum persulfate; Peroxydisulfuric acid, dipotassium salt; Dipotassium persulfate; Potassium Peroxydisulfate; Potassium peroxydisulphate; cas no: 7727-21-1
Potassium sulfate
cas no 25655-41-8 PVP-I; Poly(vinylpyrrolidone)–Iodine complex; Povadyne® antiseptic; iodopovidone;
POTLIFE ENHANCER II

Potlife Enhancer II is a high-performance additive used in polyurethane systems to extend the working time or pot life of the formulations.
Potlife Enhancer II is characterized by its efficiency in delaying the curing process, allowing for more flexibility during application.
The chemical formula for Potlife Enhancer II is proprietary, and it is commonly used in various industrial applications due to its superior properties.

CAS Number: 2425-79-8
EC Number: 219-371-7

Synonyms: Potlife extender, Potlife Enhancer II, Working time extender, Potlife Additive II, Polyurethane Additive Potlife Enhancer II, Curing Delay Agent II, Additive Potlife Enhancer II, PU Potlife Extender II, Potlife Enhancer Additive II



APPLICATIONS


Potlife Enhancer II is widely used in the formulation of polyurethane coatings, providing extended working time and flexibility during application.
Potlife Enhancer II is essential in the manufacture of high-performance polyurethane adhesives, allowing for more time to apply and adjust.
Potlife Enhancer II is utilized in the production of elastomers, enhancing their processing window and application ease.

Potlife Enhancer II is a preferred additive for flexible and rigid foams due to its efficiency in delaying the curing process.
Potlife Enhancer II is used in automotive coatings to provide more time for application and adjustments.
Potlife Enhancer II is found in the production of sealants and caulks, contributing to improved application properties.

Potlife Enhancer II is used in water-based polyurethane systems for its compatibility and efficiency in extending working time.
Potlife Enhancer II is a key component in solvent-based polyurethane coatings, providing more flexibility during application.
Potlife Enhancer II is used in the textile industry to improve the processing and application of coatings on fabrics.

Potlife Enhancer II is employed in the production of rubber materials for its ability to extend the working time.
Potlife Enhancer II is used in the manufacturing of synthetic fibers, enhancing their processing properties.
Potlife Enhancer II is used in the construction industry for high-performance coatings and sealants.

Potlife Enhancer II is used in the creation of high-performance adhesives, providing more time for application and adjustment.
Potlife Enhancer II is a key component in the production of plastics, improving their processing window and flexibility.
Potlife Enhancer II is utilized in the formulation of industrial coatings, ensuring more time for application and adjustments.

Potlife Enhancer II is applied in the creation of specialty coatings for various industrial applications, ensuring extended working time and flexibility.
Potlife Enhancer II is used in the production of coatings for metal surfaces, providing more time for application and adjustments.
Potlife Enhancer II is essential in the creation of high-quality printing inks, enhancing the working time and flexibility during printing.

Potlife Enhancer II is used in the production of rubber products, ensuring extended working time and consistent performance.
Potlife Enhancer II is employed in the automotive industry, used in high-performance coatings and adhesives for more application time.
Potlife Enhancer II is utilized in the production of wood coatings, enhancing their application properties and durability.

Potlife Enhancer II is found in the manufacture of specialty coatings for industrial machinery, providing more time for application.
Potlife Enhancer II is utilized in the formulation of adhesives and sealants, ensuring more time for application and adjustments.
Potlife Enhancer II is a key ingredient in the production of polyurethane elastomers, enhancing their processing window.

Potlife Enhancer II is employed in the textile industry to improve the performance of coatings on fabrics.
Potlife Enhancer II is used in the rubber industry for its ability to extend the working time and improve processing.
Potlife Enhancer II is essential in the production of high-performance industrial coatings, providing more application flexibility.

Potlife Enhancer II is a vital component in water-based and solvent-based polyurethane systems, ensuring extended working time.
Potlife Enhancer II is applied in the creation of high-performance industrial products, providing more time for application and adjustments.
Potlife Enhancer II is used in the formulation of household and industrial coatings, enhancing their application properties.

Potlife Enhancer II is utilized in the production of specialty coatings for electronic devices, ensuring more time for application.
Potlife Enhancer II is found in the creation of specialty inks for various applications, providing more working time.
Potlife Enhancer II is used in the production of ceramic and glass coatings, enhancing their application properties.

Potlife Enhancer II is applied in the creation of coatings for plastic surfaces, ensuring more time for application and adjustments.
Potlife Enhancer II is utilized in the formulation of coatings for wood surfaces, providing more application time.
Potlife Enhancer II is essential in the production of high-performance adhesives, ensuring more time for application and adjustments.

Potlife Enhancer II is used in the formulation of coatings for automotive applications, providing more time for application and adjustments.
Potlife Enhancer II is utilized in the production of specialty adhesives and sealants, ensuring extended working time.
Potlife Enhancer II is found in the manufacture of coatings for industrial machinery, providing more time for application.

Potlife Enhancer II is employed in the creation of specialty coatings for various substrates, ensuring more time for application and adjustments.
Potlife Enhancer II is used in the formulation of high-performance coatings for various applications, providing more time for application.
Potlife Enhancer II is a key component in the production of specialty inks for flexographic and gravure printing, providing more working time.

Potlife Enhancer II is used in the creation of specialty inks for digital printing, ensuring more time for application and adjustments.
Potlife Enhancer II is essential in the production of high-performance industrial products, providing more application flexibility.
Potlife Enhancer II is utilized in the manufacture of environmentally friendly industrial products, ensuring extended working time.

Potlife Enhancer II is used in the creation of water-based and solvent-based products, providing more time for application.
Potlife Enhancer II is a critical ingredient in the formulation of specialty coatings for metal and plastic surfaces, ensuring more application time.



DESCRIPTION


Potlife Enhancer II is a high-performance additive used in polyurethane systems to extend the working time or pot life of the formulations.
Potlife Enhancer II is characterized by its efficiency in delaying the curing process, allowing for more flexibility during application.

Potlife Enhancer II is a versatile chemical compound used in various polyurethane applications.
Potlife Enhancer II is known for its strong ability to extend the working time of polyurethane formulations, providing more time for application and adjustments.
Potlife Enhancer II provides excellent processing properties, making it ideal for industrial coatings and adhesives.

Potlife Enhancer II is compatible with a wide range of polyurethane systems, enhancing its versatility in different formulations.
Potlife Enhancer II is widely used in the coatings, adhesives, elastomers, and sealants industries, among others.
Potlife Enhancer II's non-toxic nature makes it safe for use in various industrial and consumer products.

Potlife Enhancer II offers excellent processing flexibility, making it suitable for various applications requiring extended working time.
Potlife Enhancer II is known for its ease of dispersion, ensuring uniform extension of working time in various systems.
Potlife Enhancer II is essential in the creation of durable and high-performance polyurethane products.

Potlife Enhancer II's strong ability to extend working time makes it a preferred choice in the creation of high-quality industrial coatings.
Potlife Enhancer II is an important precursor in the production of high-performance adhesives and sealants, providing more application time.
Potlife Enhancer II is widely used in the manufacture of durable and resilient polyurethane products, ensuring more time for processing and application.



PROPERTIES


Chemical Formula: Proprietary
Common Name: Potlife Enhancer II
Molecular Structure: Proprietary
Appearance: Clear liquid
Density: 1.05 g/cm³
Viscosity: Low
Solubility: Miscible with most organic solvents
Reactivity: Moderate
Chemical Stability: Excellent
Compatibility: Wide range of polyurethane systems
Processing Flexibility: Excellent
Dispersion: Easy



FIRST AID


Inhalation:
If Potlife Enhancer II is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Remove contaminated clothing and footwear.
Wash the affected skin area thoroughly with soap and water.
If skin irritation or rash develops, seek medical attention.
Launder contaminated clothing before reuse.

Eye Contact:
Flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
Do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE), including chemical-resistant gloves, safety goggles or face shield, and protective clothing.
Use respiratory protection if ventilation is insufficient or if exposure limits are exceeded.

Ventilation:
Ensure adequate ventilation in the working area to control airborne concentrations below occupational exposure limits.
Use local exhaust ventilation or other engineering controls to minimize exposure.

Avoidance:
Avoid direct skin contact and inhalation of vapors.
Do not eat, drink, or smoke while handling Potlife Enhancer II.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Use appropriate personal protective equipment.
Contain spills to prevent further release and minimize exposure.
Absorb spills with inert materials (e.g., sand, vermiculite) and collect for disposal.

Storage:
Store Potlife Enhancer II in a cool, well-ventilated area away from incompatible materials (see SDS for specific details).
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and ignition sources.

Handling Cautions:
Avoid generating aerosols or mists.
Ground and bond containers during transfer operations to prevent static electricity buildup.
Use explosion-proof electrical equipment in areas where vapors may be present.


Storage:

Temperature:
Store Potlife Enhancer II at temperatures recommended by the manufacturer.
Avoid exposure to extreme temperatures.

Containers:
Use approved containers made of compatible materials.
Check for leaks or damage in storage containers regularly.

Separation:
Store Potlife Enhancer II away from incompatible materials, including strong acids, bases, oxidizing agents, and reducing agents.

Handling Equipment:
Use dedicated equipment for handling Potlife Enhancer II to avoid cross-contamination.
Ensure all handling equipment is in good condition.

Security Measures:
Restrict access to storage areas.
Follow all applicable local regulations regarding the storage of hazardous materials.

Emergency Response:
Have emergency response equipment and materials readily available, including spill cleanup materials, fire extinguishers, and emergency eyewash stations.

POVIDONE IODINE
POVIDONE IODINE = PVP-I = IODOPOVIDONE = ISODINE


CAS Number: 25655-41-8
EC Number: 607-771-8
MDL number: MFCD00084483
Molecular formula: C6H9I2NO


Povidone iodine is a chemical complex of povidone, hydrogen iodide, and elemental iodine.
Povidone iodine contains 10% Povidone, with total iodine species equaling 10,000 ppm or 1% total titratable iodine.
Povidone iodine works by releasing iodine which results in the death of a range of microorganisms.
Povidone iodine came into commercial use in 1955.


Povidone iodine is on the World Health Organization's List of Essential Medicines.
Povidone iodine is available over the counter.
Povidone iodine is a topical antiseptic agent used for the treatment and prevention of infection in wounds.
Povidone iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine.


Povidone iodine contains from 9.0% to 12.0% available iodine, calculated on a dry basis.
Povidone iodine was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski.
During in vitro testing to demonstrate anti-bacterial activity it was found that the complex was less toxic in mice than tincture of iodine.
Povidone iodine was immediately marketed, and has since become the universally preferred iodine antiseptic.


Povidone iodine is soluble in cold and mild-warm water, ethyl alcohol, isopropyl alcohol, polyethylene glycol, and glycerol.
Povidone iodine's stability in solution is much greater than that of tincture of iodine or Lugol's solution.
Povidone iodine is a complex compound of PVP K30 and iodine, which has a powerful effect on bacteria, viruses, and molds.
Povidone iodine is stable, no irritation, completely soluble in water.



USES and APPLICATIONS of POVIDONE IODINE:
Povidone iodine is used to treat or prevent bacterial infections.
Povidone iodine may be given to you for other reasons.
All vaginal products: Povidone iodine is used to treat vaginal irritation, itching, and soreness.
Throat gargle: Povidone iodine is used to treat a sore throat.


Topical agent, Povidone iodine, is used for surgical scrubbing or other therapeutic purposes, and to protect patients from infection.
Povidone iodine is used in kitchen appliances and animal disease prevention agents in the home, food and feed industry.
Consequently, Povidone iodine has found broad application in medicine as a surgical scrub; for pre- and post-operative skin cleansing; for the treatment and prevention of infections in wounds, ulcers, cuts and burns; for the treatment of infections in decubitus ulcers and stasis ulcers; in gynecology for vaginitis associated with candidal, trichomonal or mixed infections.


For these purposes Povidone iodine has been formulated at concentrations of 7.5–10.0% in solution, spray, surgical scrub, ointment, and swab dosage forms; however, use of 10% Povidone iodine though recommended, is infrequently used, as it is poorly accepted by health care workers and is excessively slow to dry.
Because of these critical indications, only sterile Povidone iodine should be used in most cases.


Non-sterile product can be appropriate in limited circumstances in which people have intact, healthy skin that will not be compromised or cut.
The non-sterile form of Povidone iodine has a long history of intrinsic contamination with Burkholderia cepacia (aka Pseudomonas cepacia), and other opportunistic pathogens.
Povidone iodine's ability to harbor such microbes further underscores the importance of using sterile products in any clinical setting.


Since these bacteria are resistant to Povidone iodine, statements that bacteria do not develop resistance to Povidone iodine, should be regarded with great caution: some bacteria are intrinsically resistant to a range of biocides including Povidone iodine.
Povidone iodine (PVP-I), also known as iodopovidone, is an antiseptic used for skin disinfection before and after surgery.
Povidone iodine may be used both to disinfect the hands of healthcare providers and the skin of the person they are caring for.


Povidone iodine may also be used for minor wounds.
Povidone iodine may be applied to the skin as a liquid or a powder.
Antiseptic activity of Povidone iodine is because of free iodine (I2) and PVP-I only acts as carrier of I2 to the target cells.
Most commonly used 10% Povidone iodine delivers about 1-3 ppm of I2 in a compound of more than 31,600 ppm of total iodine atoms.


All the toxic and staining effects of Povidone iodineis due to the inactive iodine only.
Free iodine, slowly liberated from the Povidone iodine (PVP-I) complex in solution, kills cells through iodination of lipids and oxidation of cytoplasmic and membrane compounds.
Povidone iodine exhibits a broad range of microbiocidal activity against bacteria, fungi, protozoa, and viruses.


Slow release of iodine from the Povidone iodine complex in solution minimizes iodine toxicity towards mammalian cells.
Povidone iodine can be loaded into hydrogels, which can be based on carboxymethyl cellulose (CMC), poly(vinyl alcohol) (PVA), and gelatin, or on crosslinked polyacrylamide.
These hydrogels can be used for wound dressing.


The rate of release of the iodine in the Povidone iodine is heavily dependent on the hydrogel composition: it increases with more CMC/PVA and decreases with more gelatin.
Povidone iodine is an iodophor solution containing a water-soluble complex of iodine and polyvinylpyrrolidone (PVP) with broad microbicidal activity.


Free iodine, slowly liberated from the polyvinylpyrrolidone iodine (PVPI) complex in solution, kills eukaryotic or prokaryotic cells through iodination of lipids and oxidation of cytoplasmic and membrane compounds.
This agent exhibits a broad range of microbicidal activity against bacteria, fungi, protozoa, and viruses.
Slow release of iodine from the PVPI complex in solution minimizes iodine toxicity towards mammalian cells.


An iodinated polyvinyl polymer used as topical antiseptic in surgery and for skin and mucous membrane infections, also as aerosol.
The iodine may be radiolabeled for research purposes.
Povidone is found in both medical and household items and can cause mild symptoms with large ingestions.
Povidone iodine is a common antiseptic used to disinfect the skin, eyes, and vagina.


Because of povidone’s chemical properties, it can reduce the irritating or toxic nature of other drugs when formulated as a combination product.
Povidone is often combined with iodine for use as an antiseptic agent.
This combination product is commercially available as the skin antiseptic Betadine, but is also available in less concentrated forms for use in the eyes and vagina.


In hospital settings, povidone iodine is often used as an antiseptic agent in surgical procedures.
Recently, nasal and oral decontamination with povidone iodine has been recommended for healthcare workers as a preventive measure against COVID-19 infection.
As the effectiveness of this treatment remains unclear, the use of povidone iodine for prevention of COVID-19 remains experimental at this time.


When used as directed for antiseptic purposes, povidone iodine is generally safe.
Povidone iodine belongs to the class of 'antiseptics and disinfectants' primarily used to treat common skin infections.
Povidone iodine treats and prevents skin infections in minor burns, lacerations (deep cut in the skin), cuts, and abrasions (the first layer of skin is scraped off).


Skin infection occurs when foreign microorganisms like fungus or bacteria invade the skin and affect the tissues.
Povidone iodine may be used for other purposes.
Povidone iodine belongs to the class of 'antiseptics and disinfectants' primarily used to treat common skin infections.
Povidone iodine works by inhibiting the growth of infection-causing microbes.


As a small molecule, iodine can easily penetrate microorganisms and oxidizes essential proteins, nucleotides, and fatty acids, leading to cell death.
Povidone iodine is effective against bacteria, fungi, viruses, and protozoa.
Povidone iodine is for external use only.


Povidone iodine may cause common side effects like red or inflamed skin, peeling skin, dry skin, and irritation at the application site.
These side effects gradually resolve during the treatment and do not require medical attention.
Povidone iodine is used on the skin to decrease risk of infection.
Povidone iodine is also used as a surgical hand scrub and to wash the skin and surface of the eye before surgery to help prevent infections.


Povidone iodine can be used as a topical preservative.
Povidone iodine has activity against Gram-positive and Gram-negative bacteria, fungi, parasites, viruses and yeast.
Povidone iodine is an effective broad-spectrum antimicrobial product for pre-surgical patient preparation and post-surgical skin antisepsis.
Povidone iodine, which has an antiseptic effect in the area it is applied, is used in hygienic and surgical hand washing, preparation of surgical areas and washing around the skin.


-Uses of Povidone iodine:
*Skin infections, Cuts, Scrapes, and Burns.


-Pharmacodynamics:
Povidone iodine is a kind of iodine disinfectant which directly cause in vivo protein denaturation, precipitation of bacteria, and further resulting in the death of pathogenic microorganisms.
Therefore, it is effective in disinfection and sterilization.
Povidone iodine can kill viruses, bacteria, spores, fungi, and protozoa with low toxicity to human.
Povidone iodine aqueous solution has strong pharmacological activity against Staphylococcus aureus, Neisseria gonorrhoeae, Pseudomonas aeruginosa, syphilis, hepatitis B virus, HIV, and Trichomonas vaginalis.
Povidone iodine gel is a gynecological topical semi-mobile colloidal agent made by povidone iodine and hydrophilic matrix.
Povidone iodine is a system for maintaining its sustained release.
Owing to the continuous release of free iodine, Povidone iodine can enable the skin and mucous membranes to maintain a certain effective concentration of iodine for killing bacteria.
Povidone iodine is mainly used for gynecological vaginal infection.
Povidone iodine exerted its effect through being miscible with vaginal secretions and further killing the inside pathogenic microorganisms, and thus blocking the spread of sexually transmitted diseases and invasion, as well as treating other infected vaginal diseases caused by other kinds of bacteria.


-Medical uses of Povidone iodine:
Wound area covered in Povidone iodine.
Gauze has also been applied.
Povidone iodine is a broad spectrum antiseptic for topical application in the treatment and prevention of wound infection.
Povidone iodine may be used in first aid for minor cuts, burns, abrasions and blisters.
Povidone iodine exhibits longer lasting antiseptic effects than tincture of iodine, due to its slow absorption via soft tissue, making it the choice for longer surgeries.


-Solution uses of Povidone iodine:
Gently clean the affected area with cotton soaked in the solution.
Allow the solution to dry and cover the wound with a sterile bandage.


-Paint/Cream/Lotion/Ointment:
Take the advised amount with a sterile gauze or cotton swab and apply it to the skin's affected areas.
Cover the open wounds with a sterile dressing or bandage after application if required.
Wash your hands before and after using the product.


-Powder:
Sprinkle lightly on the affected area with or without a dressing.
-Swab sticks:
Antiseptic swabs are used to disinfect the skin before surgery and before bandaging minor cuts, scrapes and burns.
Apply the swab to the affected area to disinfect and cover with a bandage if necessary.


-External pads:
Clean the affected area thoroughly with the pad.
Discard after a single use.
-Spray:
Hold the spray container about 4-6 inches away from the skin and spray.
Allow it to dry and apply bandage/dressing, if necessary.


-Surgical scrub:
Gently apply the scrub to the affected area, develop lather and scrub thoroughly for 5 minutes.
Rinse off using sterile gauze saturated with water.
-Antisepsis of intact skin (injections, punctures):
Apply 10% solution to the puncture/injection site and allow to dry before inserting the needle.
The skin should be cleaned beforehand if soiled or if the procedure is invasive (lumbar puncture, epidural/spinal anaesthesia, etc.).


-Preoperative skin antisepsis:
Apply 10% solution twice.
Allow to dry between each application (do not dab to accelerate drying).
Incise once the 2nd application has dried.
The surgical site should be cleaned beforehand with PVI scrub solution.


-Wound antisepsis:
Apply 10% solution to small superficial wounds.
For large wounds and burns, wound irrigation, etc., dilute Povidone iodine (¼ of 10% PVI and ¾ of 0.9% NaCl or sterile water) then rinse with 0.9% NaCl or sterile water.


-Oral infections:
Povidone Iodine 5% Solution is used for the prevention and treatment of infections in the mouth.
-Minor wounds:
Povidone Iodine 5% Solution is used for the prevention and treatment of skin infection on the skin.
Povidone iodine is used as an antiseptic and first aid for minor cuts, grazes, abrasions, and blisters.


-Vaginal Candidiasis:
Povidone Iodine 5% Solution is also used to prevent and treat the fungal infection of the vagina.
Povidone iodine may be used in combination with other medicines for better results.
-Skin disinfectant:
Povidone iodine 5% Solution is also used to clean a patient's skin before a surgical procedure is performed


-Eyes:
A buffered Povidone iodine solution of 2.5% concentration can be used for prevention of neonatal conjunctivitis, especially if it is caused by Neisseria gonorrhoeae, or Chlamydia trachomatis.
It is currently unclear whether Povidone iodine is more effective in reducing the number of cases of conjunctivitis in neonates over other methods.
Povidone iodine appears to be very suitable for this purpose because, unlike other substances, it is also efficient against fungi and viruses (including HIV and Herpes simplex).


-Pleurodesis:
Povidone iodine is used in pleurodesis (fusion of the pleura because of incessant pleural effusions).
For this purpose, Povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.
-Alternatives uses of Povidone iodine:
There is strong evidence that chlorhexidine and denatured alcohol used to clean skin prior to surgery is better than any formulation of Povidone iodine.



FUNCTION of POVIDONE IODINE:
*Use skin and equipment disinfectant before injection or surgery.
*Oral, gynecological, surgical, and skin anti-infective treatment.
*Disinfecting household tableware
*In the food industry and aquaculture, disinfection can also prevent animal diseases.



MECHANISM of ACTION of POVIDONE IODINE:
Povidone iodine is called iodophore which means povidone acts as a carrier of iodine.
Iodine is considered as the active moiety that mediates microbicidal actions.
When released from the complex, free iodine (I2) penetrates the cell wall of microorganisms quickly, and the lethal effects are believed to result from disruption of protein and nucleic acid structure and synthesis.
While the full mechanism of action is not fully elucidated, iodine is thought to inhibit vital bacterial cellular mechanisms and structures, and oxidizes nucleotides fatty or amino acids in bacterial cell membranes 1.
Additionally, free iodine disrupts the function of the cytosolic enzymes involved in the respiratory chain, causing them to become denatured and deactivated 1.
In vitro evidence suggests that iodine also counteracts inflammation elicited by both pathogens and the host response via multifactorial effects.
In hosts, Povidone iodine was demonstrated to modulate the redox potential, inhibit the release of inflammatory mediators such as TNF-α and β-galactosidase, inhibit metalloproteinase production, and potentiate the healing signals from pro-inflammatory cytokines by activation of monocytes, T-lymphocytes, and macrophages, in vitro 1.



MEDICINAL BENEFITS of POVIDONE IODINE:
Povidone iodine is an antiseptic and disinfectant used to treat and prevent skin infections in minor burns, lacerations (deep cuts in the skin), cuts, and abrasions (the first layer of skin is scraped off).
Povidone iodine works by inhibiting the growth of infection-causing microbes.
Povidone iodine is effective against bacteria (gram-positive and gram-negative, including antibiotic-resistant and antiseptic-resistant strains), fungi, viruses, and protozoa.
Povidone iodine is for external use only.



ABSORPTION of POVIDONE IODINE:
Povidone iodine is intended for topical application and is not absorbed.



VOLUME of DISTRIBUTION of POVIDONE IODINE:
Povidone iodine is intended for topical application and has no volume of distribution.



INTERACTIONS of POVIDONE IODINE:
The iodine in Povidone iodine reacts with hydrogen peroxide, silver, taurolidine and proteins such as enzymes, rendering them (and itself) ineffective.
Povidone iodine also reacts with many mercury compounds, giving the corrosive compound mercury iodide, as well as with many metals, making it unsuitable for disinfecting metal piercings.
Iodine is absorbed into the body to various degrees, depending on application area and condition of the skin.
As such, Povidone iodine interacts with diagnostic tests of the thyroid gland such as radioiodine diagnostics, as well as with various diagnostic agents used on the urine and stool, for example Guaiacum resin.



STRUCTURE of POVIDONE IODINE:
Povidone iodine is a chemical complex of the polymer povidone (polyvinylpyrrolidone) and triiodide (I3−).



HISTORY of POVIDONE IODINE:
Following the discovery of iodine by Bernard Courtois in 1811, it has been broadly used for the prevention and treatment of skin infections, as well as the treatment of wounds. Iodine has been recognized as an effective broad-spectrum bactericide, and is also effective against yeasts, molds, fungi, viruses, and protozoans.
Drawbacks to its use in the form of aqueous solutions include irritation at the site of application, toxicity, and the staining of surrounding tissues.
These deficiencies were overcome by the discovery and use of Povidone iodine, in which the iodine is carried in a complexed form and the concentration of free iodine is very low.
Povidone iodine thus serves as an iodophor.
Povidone iodine was discovered in 1955, at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski.
They carried out tests in vitro to demonstrate anti-bacterial activity, and found that the complex was less toxic in mice than tincture of iodine.
Human clinical trials showed the product to be superior to other iodine formulations.



PHYSICAL and CHEMICAL PROPERTIES of POVIDONE IODINE:
Appearance Form: solid
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point Melting point/range: 300 °C
Initial boiling point and boiling range: No data available
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Density: No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available

Molecular Weight: 364.95
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 1
Monoisotopic Mass: 364.87736
Topological Polar Surface Area: 20.3 Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 120
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

Boiling Point: 217.6°C at 760 mmHg
Melting Point: 300°C
Flash Point: 93.9ºC
Solubility: Soluble in DMSO, Water
Appearance: Red-brown Crystalline Powder
Storage: Store at -20°C
HS Code: 3808940010
Log P: 2.46160
MDL: MFCD00084483
pH: 1.5-5.0
PSA: 2.31
Safety Statements: S24/25
Stability: Stable under normal temperatures and pressures.
Vapor Pressure: 0.132mmHg at 25°C
Characteristics: A red-brown,crystalline powder
Loss on drying: 8.0% max
Residue on ignition: 0.025% max
Iodine ion: 13.5% max
Heavy metals: 20ppm max
Nitrogen: 8.0%-11.5%
Assay for available iodine: 20.0%-24.0



FIRST AID MEASURES of POVIDONE IODINE:
-General advice:
Consult a physician.
-If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
-In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
-In case of eye contact:
Flush eyes with water as a precaution.
-If swallowed:
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of POVIDONE IODINE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of POVIDONE IODINE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of POVIDONE IODINE:
-Control parameters:
*Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Safety glasses with side-shields.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Choose body protection.
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of POVIDONE IODINE:
-Precautions for safe handling:
*Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage stability:
Recommended storage temperature: 2 - 8 °C



STABILITY and REACTIVITY of POVIDONE IODINE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.



SYNONYMS:
Poly(vinylpyrrolidone)–Iodine complex
PVP-I
Povadyne® antiseptic
Iodopovidone
Povidone iodine
Povidone-iodine
Povidone, iodinated
Povidone iodine
25655-41-8
Povidone-iodine
Betadine
Isodine
PVP iodine
PVP-Iodine
PVP-I
Isobetadyne
Bridine
Disphex
Povadyne
Ultradine
Efo-dine
Iodopoly(vinyl pyrrolidinone)
1-ethenylpyrrolidin-2-one;molecular iodine
NSC26245
2-Pyrrolidinone, 1-ethenyl-, homopolymer
compd. with iodinecompd. with 1-ethenyl-2-pyrrolidinone homopolymer
Iodine-poly(vinylpyrrolidinone)
Poly(vinylpyrrolidinone) iodide
Iodinated poly(vinylpyrrolidone)
Poly(vinylpyrrolidone)-iodine adduct
Poly(vinylpyrrolidinone)-iodine complex
Poly(vinylpyrrolidone) - iodine complex
Polyvinylpyrrolidone compound with iodine
povidone.iodine
1-Ethenyl-2-pyrrolidinone homopolymer compound with iodine
molecular iodine; 1-vinylpyrrolidin-2-one
1-ethenylpyrrolidin-2-one; molecular iodine
Povidone iodine-IP, 9-12%
SCHEMBL1652685
BCP28568
NSC28655
MFCD00084483
NSC-26245
NSC-28655
AKOS015898248
POLYVINYLPYRROLIDONE-IODINECOMPLEX1-ethenyl-2-pyrrolidinone
molecular iodine
FT-0655804
2-Pyrrolidinone, polymers, compd. with iodine
A16118
2-Pyrrolidinone, homopolymer, compd. with iodine
A817952
Q241516
1-vinylpyrrolidin-2-one compound with diiodine (1:1)
Poly[1-(2-oxo-1-pyrrolidinyl)ethylene]iodine complex
Povidone (iodinated)
Betadine
Isodine
PVP Iodine
Betadine
First Aid
GRx Dyne
GRx Dyne Scrub
Povidex
Povidex Peri

POVIDONE K 25
Povidone K 25 is abbreviated as PVP, and is the polymer of vinylpyrrolidone.
According to the different degree of polymerization, Povidone K 25 is further classified into soluble PVP and insoluble PVPP (polyvinyl polypyrrolidone).
Molecular weight of the soluble Povidone K 25 is 8,000 to 10,000.

CAS: 9003-39-8
MF: CH4
MW: 16.04246
EINECS: 1312995-182-4

Povidone K 25 can be used as a precipitating agent which can be settle down through its action with polyphenols. Using this method, it is easily to have residual Povidone K 25 in the alcohol.
Due to the savings effect of PVP inside the human body, the World Health Organization doesn’t recommend to apply this substance.
In recent years, the use of soluble Povidone K 25 has been rare.
Insoluble PPovidone K 25 system had began to be used in the beer industry since the early 1960s.
Povidone K 25 has a relative molecule weight greater than the relative mass greater than 700,000.
Povidone K 25 is a insoluble polymer derived from the further cross-linking and polymerization of PVP and can be used as an adsorbent of polyphenols with a good efficacy.
Povidone K 25 PVP is one of the three major pharmaceutical new excipients and can be used as the co-solvent of tablets, granules, and injection, as the glidant of capsules, as the dispersant agent of liquid preparations and the colorant, as the stabilizer of enzyme and heat sensitive drug, as the co-precipitating agent of poorly soluble drugs, and as the detoxicant of ophthalmic drugs and lubricants.
Povidone K 25 is industrially used as expanded polystyrene additive, as the gelling agents for suspension polymerization, stabilizer, and fiber treating agents, paper processing aids, adhesives, and thickening agents.
Povidone K 25 PVP and its copolymers CAP is an important raw material of cosmetics, mainly used for hair retaining agent.
The film it formed in the hair is elastic and shiny, and has excellent carding property as well as being free of dust.
Adopting different category of resin can meet various kinds of relative humidity climatic conditions.
Therefore, Povidone K 25 is an indispensable raw material in styling hair cream, hair gel, and mousse.
Povidone K 25 can also be used for the cosmetics of skin moisturizing agents and the dispersants for grease based hair dying, also as foam stabilizers, and can improve the consistency of the shampoo.
Povidone K 25 is the stabilizer of beer and juice which can improve its transparency, color, and flavor.

Povidone K 25 is a water soluble polyamide.
Commercially available Povidone K 25 is divided into four viscosity grades according to its press K value (Fikentscher K value): K-15, K-30, K-60, K-90, with the average molecular weight being 10,000, 40000,160000, and 360000, respectively.
K value or molecular weight is an important factor which decides the various properties of PVP.
Povidone K 25 is dissolved in water, chlorinated solvents, alcohol, amine, nitro-paraffin and low molecular weight fatty acids, and is mutually soluble with most inorganic salts and a variety of resin; insoluble in acetone and ether.
Povidone K 25 used for the matrix of dropping pill matrix is odorless, tasteless, white to pale yellow waxy solid with the relative density being 1.062, and its 5% aqueous solution pH being 3 to 7.
Povidone K 25 is hygroscopic and of good thermal stability, and can be dissolved in various kinds of organic solvents, and has high melting point.
Adding certain natural or synthetic polymers or organic compounds can effectively adjust the Povidone K 25’s hygroscopicity and softness.
Povidone K 25 is not prone to have chemical reaction.
Under normal storage conditions, dry Povidone K 25 is quite stable.

Povidone K 25 has excellent physical inertia and biocompatibility and has not stimulation to skin, eyes no stimulation with no allergic reactions and being non-toxic.
Because of the hydrogen bonding or complexation effect, Povidone K 25’s viscosity is increased and this further inhibits the formation and growth of crystallized nuclei of drugs, making the drug being in the amorphous state.
The dropping pill whose matrix is Povidone K 25 can enhance the dissolution and bioavailability of poorly soluble drugs.
In general, the greater the Povidone K 25 amount, the higher dissolution and solubility of drug in the medium.
Susana et al have studied the dissolution of the Povidone K 25 solid dispersant of the slightly soluble drug albendazole.
The increased amount of Povidone K 25 can increase the dissolution rate and efficiency of drug inside the solid dispersant.
Teresa et al have studied the dissolution of the poorly soluble drugs, flunarizine in Povidone K 25 solid dispersant and obtained similar conclusion.
Povidone K 25 also found that the higher the content, the more significant increase in dissolution.
IR has showed that flunarizine and Povidone K 25 has no chemical reaction except in some cases that a best dissolution efficacy is obtained only in certain ratio between some drugs with the Povidone K 25.
Tantishaiyakul et al has found that: when the ratio of piroxicam, Povidone K 25 is 1:5 and 1:6, the dissolution of the solid dispersant is the largest with a 40 times as high as that of single drug within 5min.
Povidone K 25 can also be dissolved in another molten dropping pill matrix, such as polyethylene glycol (PEG), polyoxyethylene monostearate (S-40), poloxamer and stearyl acid, glyceryl monostearate, etc for making complex matrix.

Povidone K 25 Chemical Properties
Melting point: >300 °C
Boiling point: 90-93 °C
Density: 1,69 g/cm3
Storage temp.: 2-8°C
Solubility: H2O: soluble100mg/mL
Form: powder
Color: White to yellow-white
PH: 3.0-5.0
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
Merck: 14,7697
Stability: Stable. Incompatible with strong oxidizing agents. Light sensitive. Hygroscopic.
InChI: InChI=1S/C8H15NO/c1-3-7(2)9-6-4-5-8(9)10/h7H,3-6H2,1-2H3
InChIKey: FAAHNQAYWKTLFD-UHFFFAOYSA-N
SMILES: N1(C(C)CC)C(=O)CCC1
IARC: 3 (Vol. 19, Sup 7, 71) 1987
EPA Substance Registry System: Povidone K 25 (9003-39-8)

Uses
Clarifying agent; pigment stabilizer; colloidal stabilizer; Povidone K 25 is mainly used for beer clarifying and quality stabilizing (reference amount 8~20g/100L, maintained for 24h and remove it by filtration), and can also be applied in combination with enzymes (protease) and protein adsorbents.
Povidone K 25 is also used to clarify the wine and as a stabilizer to prevent discoloration (reference amount 24~72g/100L).
Clarifying agents; stabilizers; thickeners agent; tablet fillers; dispersants; Povidone K 25 of molecular weight 360,000 are often used as the clarifying agent of beer, vinegar, and grape wine.
Used as the fixing liquid for gas chromatography.
Povidone K 25 is used as a colloidal stabilizer and clarifying agent for beer clarification.
Apply proper amount according the demands of production.
Povidone K 25 can be used for pharmacy, aquaculture, and livestock disinfectant for the sterilization of the skin and mucous.
Povidone K 25 molecule has an amide bond for absorbing the hydroxyl groups located in polyphenol molecule to form hydrogen bonds, and therefore, can be used as the stabilizer of beer, fruit wine/grape wine, and drinking wine to extend their shelf life and improve the transparency, color and taste.
Povidone K 25 have two specifications: disposable type and regeneration type.
Disposable products are suitable for application by SMEs.
Renewable products demand the purchase of special filtration equipment; but since it is recyclable, it is suitable for large breweries for recycle application.
In daily cosmetics, Povidone K 25 and its copolymer has good dispersion property and filming property, and thus being able to be used as a setting lotion, hair spray and styling mousse, as opacifiers for hair care agents, as the stabilizer of shampoo foam, as wave styling agent and as the dispersants and affinity agents in hair dye.
Adding Povidone K 25 to cream, sunscreen, and hair removal agent can enhance wetting and lubricating effect.
Taking advantage of the excellent properties of Povidone K 25 such as surface activity, film-forming and non-irritating to the skin, no allergic reactions, etc., has broad prospects in its application in hair care and skin care products.

Povidone K 25 is used as an adhesive in glue sticks; an emulsifier and a disintegrant for solution polymerization; an additive to Doro's RNA extraction buffer; as a liquid-phase dispersion enhancing agent in diffusion-ordered spectroscopy (DOSY) NMR and as a thickening agent in tooth whitening gels.
Povidone K 25 finds use in personal care products like shampoos and toothpastes, in ink for inkjet printers as well as in contact lens solutions.
Povidone K 25 is used as a food additive and in the wine industry as a fining agent for white wine.
Povidone K 25 is used as a capping agent to synthesize silver nanowires through a polyol process.
Povidone K 25 has been used:
To perform intracytoplasmic sperm injection procedure
In the preparation of endophyte coating agent mixture, to coat creeping bentgrass seed
As a component of prehybridization solution

Medical
Povidone K 25 is used as a binder in many pharmaceutical tablets; it simply passes through the body when taken orally.
Povidone K 25 added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.
Povidone K 25 is used in various products such as solutions, ointment, pessaries, liquid soaps, and surgical scrubs. Povidone K 25 is sold under the trade names Pyodine and Betadine, among others.
Povidone K 25 is used in pleurodesis (fusion of the pleura because of incessant pleural effusions).
For this purpose, Povidone K 25 is as effective and safe as talc, and may be preferred because of easy availability and low cost.
Povidone K 25 is used in some contact lenses and their packaging solutions.
Povidone K 25 reduces friction, thus acting as a lubricant, or wetting agent, built into the lens.
Examples of Povidone K 25 use include Bausch & Lomb's Ultra contact lenses with MoistureSeal Technology and Air Optix contact lens packaging solution (as an ingredient called "copolymer 845").
Povidone K 25 is used as a lubricant in some eye drops, e.g. Bausch & Lomb's Soothe.
Povidone K 25 was used as a plasma volume expander for trauma victims after the 1950s.
Povidone K 25 is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping.
Autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.
The long-term effects of crospovidone or povidone within the lung are unknown.

Preparation
N -Vinylpyrrolidone is water-soluble and is usually polymerized in aqueous solution at about 50C with ammonia and hydrogen peroxide.
The polymer is also water-soluble and is isolated by spray-drying.
Commercial grades of polyvinylpyrrolidone (PVP) have average molecular weights (Mv) ranging from about 10000 up to 360000.
The largest use of Povidone K 25 is in cosmetic formulations, especially hair lacquers.
In the latter applications, Povidone K 25 is the preferred film-former on account of good adhesion to hair, lustre of the film and ease of removal on washing.
Povidone K 25 is also used as a binder in pharmaceutical tablets.
Povidone K 25 also finds use in the textile industry, particularly in colour stripping operations, where the great affinity of the polymer for dyestuffs is utilized.
An interesting application of Povidone K 25 is in aqueous solution as a blood plasma substitute; such material was extensively used in Germany during the Second World War.

Production method
Povidone K 25's crude product comes from the polymerization of vinylpyrrolidone under basic catalyst or the existence of N, N'-divinyl amidine and further cross-inking reaction.
Then use water, 5% acetic acid and 50% ethanol for reflux to until extract ≤50mg/kg (for over 3h).
The 30% to 60% aqueous solution of the purified 1-vinyl-2-pyrrolidone, in the presence of ammonia or amines and also with hydrogen peroxide as the catalyst, has cross-linking and homo-polymerization reaction at a temperature of 50 °C and subject to further purification to obtain the final product.

Production Methods
Povidone K 25 is manufactured by the Reppe process.
Acetylene and formaldehyde are reacted in the presence of a highly active copper acetylide catalyst to form butynediol, which is hydrogenated to butanediol and then cyclodehydrogenated to form butyrolactone.
Pyrrolidone is produced by reacting butyrolactone with ammonia.
This is followed by a vinylation reaction in which pyrrolidone and acetylene are reacted under pressure.
The monomer, vinylpyrrolidone, is then polymerized in the presence of a combination of catalysts to produce Povidone K 25.

Synonyms
N-VINYL-2-PYRROLIDONE
88-12-0
1-vinylpyrrolidin-2-one
N-Vinylpyrrolidone
1-Vinyl-2-pyrrolidone
9003-39-8
1-Vinyl-2-pyrrolidinone
N-Vinyl-2-pyrrolidinone
Povidone
Vinylpyrrolidone
N-Vinylpyrrolidinone
1-ethenylpyrrolidin-2-one
2-Pyrrolidinone, 1-ethenyl-
1-Vinylpyrrolidone
Pvpp
Vinylbutyrolactam
Vinylpyrrolidinone
V-Pyrol
Luviskol
Plasdone
1-Vinylpyrrolidinone
25249-54-1
Vinyl-2-pyrrolidone
N-Vinyl pyrrolidone
1-Ethenyl-2-pyrrolidinone
N-Vinylpyrrolidone-2
1-Vinyl-2-pyrrolidinone, monomer
2-Pyrrolidinone, 1-vinyl-
PVP
NSC 10222
MPK 90
PVP 40
DTXSID2021440
143 RP
AT 717
1-vinyl-pyrrolidin-2-one
K 15
K 90
PVP-40
CHEBI:82551
MFCD00003197
NSC-10222
76H9G81541
DTXCID101440
WLN: /T5NVTJ AY*1*/
MFCD01076626
CAS-88-12-0
K 25
K 115
HSDB 7231
EINECS 201-800-4
BRN 0110513
CCRIS 8581
PovidonePVP
vinyl pyrrolidone
UNII-76H9G81541
N-vinyl-pyrrolidone
N -vinylpyrrolidinone
1-vinyl-2-pyrrolidon
POVIDONE MONOMER
VINYLBUTYLOLACTAM
N-vinylpyrrolidin-2-one
?N-Vinyl-2-pyrrolidone
N-vinyl pyrrolidin-2-one
N-vinyl-pyrrolidin-2-one
Crospovidone ~40,000
EC 201-800-4
SCHEMBL10869
WLN: T5NVTJ A1U1
PVP-K30
POVIDONE MONOMER [MI]
VINYL PYRROLIDONE (VP)
CHEMBL1878943
N-VINYL PYRROLIDONE [INCI]
1-Vinyl-2-pyrrolidone(stabilized with 200ppm Ammonium hydroxide)
NSC10222
Tox21_202462
Tox21_300073
NSC114022
NSC142693
NSC683040
Polyvinylpyrrolidone (MW ~40,000)
AKOS000119985
N-VINYL-2-PYRROLIDONE [IARC]
AT18510
CS-W020981
FG-0420
NSC-114022
NSC-142693
NSC-683040
NCGC00166252-01
NCGC00166252-02
NCGC00166252-03
NCGC00254200-01
NCGC00260011-01
2-PYRROLIDINONE, 1-ETHENYL- [HSDB]
FT-0608329
FT-0645144
FT-0655284
V0026
EN300-19745
C19548
A817742
A843417
Q420628
SR-01000944531
J-015891
SR-01000944531-1
W-100417
1-Vinyl-2-pyrrolidinone, SAJ first grade, >=99.0%
F8881-5579
Z104475034
3-CHLORO-5,6-DIFLUORO-1-BENZOTHIOPHENE-2-CARBONYLCHLORIDE
InChI=1/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H
1-Vinyl-2-pyrrolidinone, contains sodium hydroxide as inhibitor, >=99%
1-Vinyl-2-pyrrolidinone, Pharmaceutical Secondary Standard; Certified Reference Material
1-Vinyl-2-pyrrolidone (stabilized with N,N'-Di-sec-butyl-p-phenylenediamine)
POVIDONE K 30 (PVP K 30)
Povidone K 30 (PVP K 30) has important features to provide flexibility in wet granulation applications.
Povidone K 30 (PVP K 30) has a spherical particle morphology.


CAS Number: 9003-39-8
ECNumber: 1312995-182-4
MDL Number: MFCD00149016
Molecular Formula: (C6H9NO)n



SYNONYMS:
n-vinyl-2-pyrrolidone, n-vinylpyrrolidone, 1-vinyl-2-pyrrolidone, 1-vinylpyrrolidin-2-one, n-vinyl-2-pyrrolidinone, vinylpyrrolidone, 2-pyrrolidinone, 1-ethenyl, 1-vinyl-2-pyrrolidinone, n-vinylpyrrolidinone, 1-vinylpyrrolidone, Povidone K-30, povidone iodine, copovidone S630., povidone K90, polyvinylpyrrolidone PVP K-30, Polyvinylpyrrolidone, Polyvinyl pyrrolidone, PVP, Polyvidone, 1-Ethenylpyrrolidin-2-one, Copovidone, PVPP,
Poly[1-(2-oxo-1-pyrrolidinyl)ethylene] , Polyvinylpyrrolidone , PVP , Povidone, PVP K 30, Polyvidone, Povidone, Plasdone , PVP, Poly[1-(2-oxo-1-pyrrolidinyl)ethylene], Polyvinylpyrrolidone, PVP, Povidone, polyvinylpyrrolidone, povidone, Pvp K-90, Pvp K-30, Pvp K-25, pyrrolidone, N-Vinylpyrrolidone, N-Vinyl-2-Pyrrolidone, Vinylpyrrolidone, 1-Vinyl-2-Pyrrolidone, polyvidone, Povidone K30, PVP-K 30, Povidone K29/32, 1-vinylpyrrolidin-2-one homopolymer, PVP K-30, PVP K30, Plasdone K29-32, Plasdone K29/32, Polyvinylpyrrolidone K 30, Polyvinylpyrrolidone K-29/32, Polyvinylpyrrolidone K30, Povidone K29-32, U725QWY32X, 390RMW2PEQ, KOLLIDON 30 LP, PLASDONE C-30, PLASDONE C30, POVIDONE IMPURITY A (EP IMPURITY), POVIDONE K29/32 (II), POVIDONE K30 (II), PVP, K-30, PVP-K, PVP-K30, PVP-K17, PVP-K25, PVP-K90, Povidone, PVP K 30, Crospovidone, Polyinylpyrrolidone, Polyvinylpyrrolidine, Polyvinylpyrrolidone, Polyvinglpyrrolidone, Polyvinyl pyrrolidone, poly vinyl pyrrolidone



Povidone K 30 (PVP K 30) is abbreviated as PVP.
Vinyl is the polymer of Pyrrolidone.
Povidone K 30 (PVP K 30) is the 3 major major pharmaceutical excipients.


Povidone K 30 (PVP K 30) is a water-soluble synthetic polymer made from N-Vinyl Pyrrolidone monomer.
Viscosity and adhesion strength are determined thanks to different molecular weights.
The higher the molecular weight, the stronger Povidone K 30 (PVP K 30)'s viscosity and adhesion force will be.


Povidone K 30 (PVP K 30) has an important place in the selection of wet granulation binders.
Povidone K 30 (PVP K 30) has important features to provide flexibility in wet granulation applications.
Povidone K 30 (PVP K 30) has a spherical particle morphology.


Povidone K 30 (PVP K 30) is soluble in water and many organic solvents and it forms hard, transparent, glossy film.
Povidone K 30 (PVP K 30) is compatible with most inorganic salts and many resins.
Povidone K 30 (PVP K 30) stabilizes emulsions, dispersions and suspensions.


Povidone K 30 (PVP K 30)appears as a white powder.
Povidone K 30 (PVP K 30), also known as polyvinylpyrrolidone or polyvidone, is a polymer and used as a binder in pharmaceutical tablets.
Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.


A polyvinyl polymer of variable molecular weight; Povidone K 30 (PVP K 30) is used as suspending and dispersing agent and vehicle for pharmaceuticals.
Povidone K 30 (PVP K 30), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone.
Povidone K 30 (PVP K 30) acts as a stabilizer and film former.


Povidone K 30 (PVP K 30) provides strong and stiff hold.
Povidone K 30 (PVP K 30) is a hygroscopic and amorphous polyvinylpyrrolidone polymer powder.
Povidone K 30 (PVP K 30) shows excellent compatibility with acrylate thickeners.


Povidone K 30 (PVP K 30) stabilizes foam, emulsions, dispersions and suspensions.
Povidone K 30 (PVP K 30) finds application in formulating hair care products like sprays, mousses, gels, styling lotions/creams, colorants and novelty stylers.


Povidone K 30 (PVP K 30) forms clear, hard, shiny and glossy films.
Povidone K 30 (PVP K 30) is soluble in water and methyl alcohol
Povidone K 30 (PVP K 30) is a chemical with hygroscopic properties


The purpose of using Povidone K 30 (PVP K 30) in the cosmetics field is to benefit from its ability to form a hard and at the same time bright transparent film as a dispersion agent.
Povidone K 30 (PVP K 30) is a substance that is highly compatible with many chemicals.


A polyvinyl polymer of variable molecular weight; Povidone K 30 (PVP K 30) is used as suspending and dispersing agent and vehicle for pharmaceuticals.
Povidone K 30 (PVP K 30) has the molecular formula of (C6H9NO)n and appears as a white to slightly off-white powder.
Povidone formulations are widely used in the pharmaceutical industry due to their ability to dissolve in both water and oil solvents.


The k number refers to the mean molecular weight of the povidone. Povidones with higher K-values (i.e., k90) are not usually given by injection due to their high molecular weights.
The higher molecular weights prevent excretion by the kidneys and lead to accumulation in the body.


The best-known example of povidone formulations is povidone-iodine, an important disinfectant.
Povidone K 30 (PVP K 30), also commonly called Polyvidone or Povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone.
Povidone K 30 (PVP K 30), commonly known as polyvidone or povidone, is a water-soluble polymer created from the monomer N-vinylpyrrolidone.


Povidone K 30 (PVP K 30) is also utilized in numerous technological applications, such as hot-melt adhesives and glue sticks. batteries, ceramics, fiberglass, inks, inkjet paper, and in the chemical-mechanical planarization process as a specific additive.
Povidone K 30 (PVP K 30) acts as a stabiliser and film former, providing a strong and stiff hold.


Povidone K 30 (PVP K 30) is a hygroscopic and amorphous polyvinylpyrrolidone polymer powder that shows excellent compatibility with acrylate thickeners.
Povidone K 30 (PVP K 30) is water-soluble, and is compatible with most inorganic salts and many resins.
Povidone K 30 (PVP K 30) is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder.


Povidone K 30 (PVP K 30) can be plasticized with water and most common organic plasticizers.
Povidone K 30 (PVP K 30) is considered to be physiologically inert.
Povidone K 30 (PVP K 30) is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry.


PVP products are recommended for dishwashing, fabric care, household cleaning, and industrial and institutional cleaning applications.
Povidone K 30 (PVP K 30) acts as a film former and stabilizer.
Povidone K 30 (PVP K 30) forms clear, hard, shiny and glossy films.


Povidone K 30 (PVP K 30) is a 30% hygroscopic and amorphous polyvinylpyrrolidone solution.
Povidone K 30 (PVP K 30) provides strong and stiff hold.
Povidone K 30 (PVP K 30) has excellent compatibility with acrylate thickeners.


Povidone K 30 (PVP K 30), also commercially known as K30, is a water soluble polymer.
Povidone K 30 (PVP K 30) has a hygroscopic nature with good adhesive properties.
Povidone K 30 (PVP K 30) has a stable pH and has the ability to form transparent films.


Povidone K 30 (PVP K 30) is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.
Povidone K 30 (PVP K 30), also known as Polyvinylpyrrolidone K30, is a synthetic polymer produced from the monomer vinylpyrrolidone.
Povidone K 30 (PVP K 30) is a white, free-flowing powder with a high molecular weight.


Povidone K 30 (PVP K 30) is water-soluble and has excellent film-forming and adhesive properties.
In cosmetics and personal care products, Povidone K 30 (PVP K 30) is utilized as a stabilizer, thickener, and film-forming agent in various applications such as hair gels, hair sprays, and skin care products.


Povidone K 30 (PVP K 30) stabilizes foam, emulsions, dispersions and suspensions.
Povidone K 30 (PVP K 30) finds application in formulating hair care products like sprays, mousses, gels, styling lotions/creams, colorants and novelty stylers.


Povidone K 30 (PVP K 30) is soluble in water and many organic solvents and it forms hard, transparent, glossy film.
Povidone K 30 (PVP K 30) stabilizes emulsions, dispersions and suspensions. While Povidone K 30 (PVP K 30) is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants.


Povidone K 30 (PVP K 30) is a white powder, with slightly odor.
Povidone K 30 (PVP K 30) is hygroscopic.
Povidone K 30 (PVP K 30) is soluble in water, ethanol, ether and other organic solvents.


Povidone K 30 (PVP K 30) has a wide range of usage such as:an adhesive for making gluesticks and metal adhesivesa dispersant for ceramicscoatings and inksformation of synthetic fibres and textilesporous membranes
Povidone K 30 (PVP K 30) is compatible with most inorganic salts and many resins.



USES and APPLICATIONS of POVIDONE K 30 (PVP K 30):
Povidone K 30 (PVP K 30) is used to clarify beer in beer production.
Povidone K 30 (PVP K 30) is the raw material used to retain and filter sediments to clarify wine.
Povidone K 30 (PVP K 30) is used in the manufacture of hair sprays to provide a thin film layer on the hair with a shiny and wet lubricating effect.


Povidone K 30 (PVP K 30) is a good stabilizer for creatine in skin care and lotions in the cosmetic industry.
Povidone K 30 (PVP K 30) may be used as an emulsion stabiliser in creams and lotions, and as a dispersant for hair colourants.
Povidone K 30 (PVP K 30) is a compound which has been widely tested and used in human and veterinary medicine as an effective wound healing accelerator and disinfectant when combined with iodine and other compounds.


Povidone K 30 (PVP K 30) is used as stationary liquid for gas chromatography
Povidone K 30 (PVP K 30) is used to create a complex in the production of cosmetic products containing AHA and BEHA to eliminate fine lines on the skin and revitalize aging skin.


Povidone K 30 (PVP K 30) is used as a base stock product in lipstick manufacturing.
In the recycling industry, Povidone K 30 (PVP K 30) is used as a binder to prevent glass fiber from disintegrating during cutting with a guillotine.
Povidone K 30 (PVP K 30) is used to reduce some undesirable effects on the skin due to its detoxification effect.


Some dirt remains suspended during fabric washing.
Povidone K 30 (PVP K 30) is used to prevent the re-accumulation of suspended dirt.
Povidone K 30 (PVP K 30) finds application in formulating hair care products like sprays, mousses, gels, styling lotions/creams, colourants and novelty stylers.


Povidone K 30 (PVP K 30) is used as a thickener and as a dispersing agent.
Povidone K 30 (PVP K 30) is also used as a detoxicant, a complexing agent, a lubricant and a binder.
Povidone K 30 (PVP K 30) stabilises foam, emulsions, dispersions, and suspensions.


Povidone K 30 (PVP K 30) is used as a bulking agent in tablets and sachets.
Povidone K 30 (PVP K 30) is a synthetic polymer used in the manufacture of hair sprays and wavy hair styling lotions.
Povidone K 30 (PVP K 30) is used to increase the solubility of active substances with low solubility in drug delivery systems.


By increasing the amount of Povidone K 30 (PVP K 30), it can further increase the dissolution rate and effectiveness of the drug in the solid dispersant.
Povidone K 30 (PVP K 30) is used as a thickening agent to prevent fading in titanium and titanium alloy facade coatings.
In addition, Povidone K 30 (PVP K 30) is also used as a thickener in these applications .


Povidone K 30 (PVP K 30) is used as a dispersing agent of liquid preparations.
Povidone K 30 (PVP K 30) provides stabilization of drug derivatives such as heat-sensitive enzymes.
Povidone K 30 (PVP K 30) is used as a binding agent in the production of effervescent tablets used in dysphagia treatments.


Povidone K 30 (PVP K 30) is used as a binding agent in citrate-containing cough tablets taken orally.
The most common usage areas of Povidone K 30 (PVP K 30) are pharmaceuticals and cosmetics.
Povidone K 30 (PVP K 30) form is used in the cosmetics industry.


The purpose of using Povidone K 30 (PVP K 30) in the cosmetics industry is to benefit from its ability to form a hard and at the same time bright transparent film as a dispersion agent.
Povidone K 30 (PVP K 30) is generally used in the pharmaceutical and cosmetic industry


Povidone K 30 (PVP K 30) is used as a thickening agent in teeth whitening gels.
Povidone K 30 (PVP K 30) is used in the production of membranes such as water and dialysis.
Povidone K 30 (PVP K 30) is used as a stabilizing agent in the production of all inorganic solar cells.


Povidone K 30 (PVP K 30) is used in personal care products such as shampoos and toothpastes, paints, and adhesives that need to be moistened, such as old-style postage stamps and envelopes.
Povidone K 30 (PVP K 30) is used in the production of adhesives used to combine rubber with metal.


Povidone K 30 (PVP K 30) is used as a binding agent for tablets and capsules.
Povidone K 30 (PVP K 30) is also used as blood volume expander. See [povidone] for full details.
While PVP is used as a film former in hair styling products, Povidone K 30 (PVP K 30) can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants.


Additionally, pharmaceutical grade Povidone K 30 (PVP K 30) can be used in toothpastes and mouthwashes.
Povidone K 30 (PVP K 30) is also used as blood volume expander.
Povidone K 30 (PVP K 30) is used as a stabilizing agent in all inorganic solar cells.


Among the usage areas of Povidone K 30 (PVP K 30), the most common sector is pharmaceutical and cosmetics.
The purpose of using Povidone K 30 (PVP K 30) in the cosmetics industry is to benefit from its ability to form a hard and at the same time bright transparent film as a dispersion agent.


In the adhesive industry, in the manufacture of pressure-sensitive adhesives, as a grinding stone binder, and as a viscosity changing agent in the production of ceramic type products prepared with high temperatures.
It is an important ingredient in hair sprays and lotions used to create wavy hair.


This synthetic polymer can be Povidone K 30 (PVP K 30) or Pvp K-90.
Povidone K 30 (PVP K 30) is used in the manufacture of adhesives used to bond rubber to metal.
Povidone K 30 (PVP K 30) is used as a protective colloid and leveling agent in digital printing coating materials, ballpoint inks and emulsion polymers.


In the electronics industry, Povidone K 30 (PVP K 30) is used as a binding agent in cathode ray tubes, printed circuits and storage batteries.
Povidone K 30 (PVP K 30) is used to disperse titanium dioxide used in the textile industry.
Povidone K 30 (PVP K 30) is used in the manufacturing of coating components used on the surface of aluminum, copper, zinc and nickel metals in the coating industry.


Povidone K 30 (PVP K 30) is an excipient used in pharmaceutical products to disperse and suspend drugs.
Povidone K 30 (PVP K 30) is used in the production of pill form drugs used to relieve cold discomfort.
Povidone K 30 (PVP K 30) is used as a binding agent in the production of tablets used in the dishwasher.


Povidone K 30 (PVP K 30) is used as a binding agent for tablets and capsules.
Povidone K 30 (PVP K 30) is used as a binder and complexing agent in agricultural applications such as plant protection, seed treatment and coating.
Povidone K 30 (PVP K 30) is used as a thickening agent in teeth whitening gels.


Povidone K 30 (PVP K 30) is used in the production of membranes such as water and dialysis.
Povidone K 30 (PVP K 30) is used as a stabilizing agent in the production of all inorganic Solar cells.
Povidone K 30 (PVP K 30) is used in personal care products such as shampoos and toothpastes, paints, and adhesives that need to be moistened, such as old-style postage stamps and envelopes.


Povidone K 30 (PVP K 30) helps clarify the wine by removing sediments in wine production.
In the cosmetic industry, Povidone K 30 (PVP K 30) is used as a complexing agent in the manufacture of skin care products and anti-aging products containing AHA-BHA.


Povidone K 30 (PVP K 30) is used as thickeners, dispersing agents, detoxicant, complexing agent, lubricants and binders.
Povidone K 30 (PVP K 30) is a component of Denhardt′s Solution.
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.


Key Applications of Povidone K 30 (PVP K 30): Thickeners | Dispersing agents | Detoxicant | Complexing agent.
Povidone K 30 (PVP K 30) is used in the pharmaceutical industry as a synthetic polymer vehicle for dispersing and suspending drugs.
Povidone K 30 (PVP K 30) has multiple uses, including as a binder for tablets and capsules, a film former for ophthalmic solutions, to aid in flavoring liquids and chewable tablets, and as an adhesive for transdermal systems.


Povidone K 30 (PVP K 30) is used as a disintegrant and emulsifier in the solution polymerization process.
Commercial Use: Povidone K 30 (PVP K 30) is widely used in Food Industry & Beverage industry.
Povidone K 30 (PVP K 30) is used as binders in tablets, capsules & granules, stabilizers in oral suspensions, film formers, dispersants for pigments, thickeners and bioavailability improver.


Povidone K 30 (PVP K 30) is used in the pharmaceutical industry as a synthetic polymer vehicle for dispersing and suspending drugs.
Povidone K 30 (PVP K 30) has multiple uses, including as a binder for tablets and capsules, a film former for ophthalmic solutions, to aid in flavoring liquids and chewable tablets, and as an adhesive for transdermal systems


Applications of Povidone K 30 (PVP K 30): Technical grade PVP are being used in Textiles/Fibers, Adhesives, Coatings/paintings, Laundry/Household detergent, Inks, Ceramics and other hi-tech industries.
Additionally, pharmaceutical grade Povidone K 30 (PVP K 30) can be used in toothpastes and mouthwashes.


Povidone K 30 (PVP K 30) is used in several industries like adhesives, ceramics, glass and glass-fiber, inks and coatings, electronic appliances, lithography and photography, fibers and textiles, membranes, metallurgy, paper, etc.
Povidone K 30 (PVP K 30) is used in the pharmaceutical industry as a binder in tablet formulations, improving the cohesion of tablet ingredients.
Povidone K 30 (PVP K 30) is used for a variety of substances have a strong ability to complex adsorption.



HOW TO PRODUCE POVIDONE K 30 (PVP K 30):
How to Produce Pvp K-30?
Povidone K 30 (PVP K 30) production comes from the presence of N,N'- divinyl amide as a result of the polymerization of Vinylpyrrolidone under a basic catalyst and the cross-inking reaction.

Povidone K 30 (PVP K 30) is refluxed using a certain concentration of Acetic Acid and Ethyl Alcohol until it is extracted during the production process .
Povidone K 30 (PVP K 30) is obtained in the presence of Ammonia and some Amines and also with Hydrogen Peroxide as catalyst. After further purification, Povidone K 30 (PVP K 30) is obtained.



BENEFITS OF POVIDONE K 30 (PVP K 30):
• Stabilised emulsions
• Water soluble
• Compatible with inorganic salts
• Forms a hard film



WHAT ARE POVIDONE K 30 (PVP K 30)'S PHYSICAL AND CHEMICAL PROPERTIES?
In physical appearance, Povidone K 30 (PVP K 30) is in the form of a free-flowing white powder.
Povidone K 30 (PVP K 30) is hygroscopic.
Povidone K 30 (PVP K 30)'s density is 1.69 g/cm³.

Povidone K 30 (PVP K 30)'s melting point is over 300 °C.
Povidone K 30 (PVP K 30)'s boiling point is in the range of 90-93 °C.
Povidone K 30 (PVP K 30) is stable under normal conditions.

But Povidone K 30 (PVP K 30) is not compatible with strong oxidizing agents.
Povidone K 30 (PVP K 30) has good solubility in water.
However, Povidone K 30 (PVP K 30) becomes insoluble when mixed with Ammonium Persulfate .

Povidone K 30 (PVP K 30) gels in the presence of light and Dichromate oxidizing compounds.
These dichromate compounds can be Sodium Dichromate (Sodium Bichromate) .
Povidone K 30 (PVP K 30) is soluble in many organic solvents and produces some viscosities.
The viscosity of these organic solvents varies depending on their structure.



MECHANISM OF ACTION OF POVIDONE K 30 (PVP K 30):
Povidone K 30 (PVP K 30) is a water-soluble complex that mediates a bactericidal or virucidal action following the gradual liberation of free iodine from the complex at the application site to react with the pathogen 1.
Please refer to the drug entry for Povidone K 30 (PVP K 30) for the full mechanism of action of the complex.



PREPARATION METHOD OF POVIDONE K 30 (PVP K 30):
Povidone K 30 (PVP K 30) is obtained by polymerizing n-vinyl-2-pyrrolidone in the presence of a basic catalyst or N,N'-vinyltriazole, followed by purification.

Povidone K 30 (PVP K 30) is obtained by polymerizing pyrrolidone and ethylene under pressure to form a vinyl pyrrolidone monomer by the action of a catalyst.
1-vinyl-2-pyrrolidone homopolymer having an average molecular weight of 3.8x 104 and a molecular formula of (C6H9NO)n, where n represents the average number of 1-vinyl-2-pyrrolidone moieties.



BENEFITS OF POVIDONE K 30 (PVP K 30):
- For use in enhancing liquid flavor
- Binds different Ingredients together
- Stabilizes Emulsion & Dispersion
- Maintain the viscosity of formula



PHYSICAL and CHEMICAL PROPERTIES of POVIDONE K 30 (PVP K 30):
CAS Number: 9003-39-8
Formula: (C6H9NO)n
Molecular Weight: 111.14 g/mol
Density: 1.2 g/cm³
Melting Point: 150-180°C
Appearance: White, solid
pH Value: 3.3
K-Value: 30.7
Residue from Combustion: 0.07%
Bullet: < 10 ppm
Aldehydes: 0.06%
Hydramines: < 1 ppm
Categories: Polymer science compounds, Hydrophilic polymers
Assay: 11.5-12.8%

Appearance (Form): Powder
Appearance (Colour): White
Maximum Limits of Impurities:
Residual Monomer Content: 0.8%
Water Content: 5%
Sulphate Ash: 0.02%
pH: 3-7
K-Value: 27-32.4
Viscosity at 25°C (5% aqueous solution): About 2.4 cP
Boiling Point/Range: 90-93°C
Molecular Formula: C6H13NO2P2
Molecular Weight: 177.12 g/mol

Appearance (Colour): White to off-white
CAS Number: 9003-39-8
Molecular Formula: (C6H9NO)n
Molecular Weight: 111.144 g/mol
MDL Number: MFCD00149016 / MFCD01076626
Appearance (Colour): White to off-white
Appearance (Form): Crystalline powder
Solubility (Turbidity) 10% aqueous solution: Clear
Nitrogen (N): 11.5 - 12.5%
pH (5% aqueous solution): 3.0 - 7.0
Sulphated Ash: Max. 0.1%
Heavy Metals (Pb): Max. 0.001%
K-value: ~30
Vinyl Pyrrolidone: Max. 0.8%

Water (KF): Max. 5%
Aldehydes: Max. 0.05%
Peroxides: Max. 0.04%
Formic Acid (HPLC): Max. 0.5%
Hydrazine by TLC: Max. 0.00001%
Impurity A: Max. 0.001%
Impurity B: Max. 3.0%
Physical State (20°C): Solid
Storage: Room temperature (Recommended in a cool and dark place, <15°C)
Shelf Life: 60 months
HSN Code: 29420090
PubChem Substance ID: 87574663
Merck Index (14): 7697
Condition to Avoid: Hygroscopic

Store Under Inert Gas: Yes
CAS Number: 9003-39-8
Molecular Formula: (C6H9NO)n
Molecular Weight: 111.14 g/mol
MDL Number: MFCD01076626
InChI Key: WHNWPMSKXPGLAX-UHFFFAOYSA-N
PubChem CID: 6917
ChEBI ID: CHEBI:82551
IUPAC Name: 1-ethenylpyrrolidin-2-one
SMILES: -CC(-)N1CCCC1=O
Density: 1.23–1.29 g/mL (lit.)
pH (5% aqueous solution): 2.8 to 4.2
Viscosity: 27–35 cps (1% aqueous solution)

Solubility: Soluble in water (>100 mg/mL, 2.5% aq solution), methanol,
ethanol, alcohol, chloroform, glycerol, acetic acid;
insoluble in dimethyl ether, ethyl acetate, acetone,
toluene, xylene, mineral oil, carbon tetrachloride.
Melting Point: 130°C
Boiling Point: 90-93°C
Water Solubility: ≥10 g/100 mL at 20°C
Physical Form: Powder
Grade: Molecular Biology (MB)
Storage Condition: Room Temperature
Formula Weight: 35,000–51,000
Molar Mass: 111.143 g/mol



FIRST AID MEASURES of POVIDONE K 30 (PVP K 30):
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available



ACCIDENTAL RELEASE MEASURES of POVIDONE K 30 (PVP K 30):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of POVIDONE K 30 (PVP K 30):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of POVIDONE K 30 (PVP K 30):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of POVIDONE K 30 (PVP K 30):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of POVIDONE K 30 (PVP K 30):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available


POVIDONE K 90

Povidone K 90, also known simply as Povidone or Polyvinylpyrrolidone (PVP), is a polymer that belongs to a group of water-soluble polymers.
Povidone K 90 is a type of polyvinylpyrrolidone with a specific molecular weight range.
Povidone K 90 is widely used in the pharmaceutical, cosmetic, and personal care industries for its various properties.

CAS Number: 9003-39-8
EC Number: 284-284-2

Polyvinylpyrrolidone, PVP, Povidone K 90, Povidone K30, PVP K30, PVP K90, PVP-I, Polyvidone, Poly[N-vinylpyrrolidin-2-one], Crospovidone, PVPP, N-Vinyl-2-pyrrolidinone polymer, E1201, 1-Ethenyl-2-pyrrolidinone polymer, 1-Vinyl-2-pyrrolidinone polymer, N-Vinylpyrrolidone homopolymer, Polyvidonum, Povidone K15, Povidone K17, Povidone K25, Povidone K29/32, Povidone K60, Povidone K85, PVP iodine complex, PVP/VA copolymer, PVP/VA S-630, PVP/VA 64, PVP/VA W-735, PVP/VA E-335, PVP/VA 73W, PVP/VA 64P, PVP/VA S-630 (W), PVP/VA 73W (W), PVP/VA 735, PVP/VA W-735 (W), PVP/VA 64L, PVP/VA 735L, PVP/VA E-335 (W), PVP/VA S-333, PVP/VA E-335 (W) (W), PVP/VA 73L, PVP/VA W-930, PVP/VA 923, PVP/VA 64L (W), PVP/VA W-930 (W), PVP/VA 923L, PVP/VA 64P (W), PVP/VA E-335 (W) (W), PVP/VA S-630 (W) (W), PVP/VA 73W (W) (W), PVP/VA 64L (W) (W), PVP/VA W-735 (W) (W), PVP/VA 735L (W) (W), PVP/VA W-930 (W) (W), PVP/VA 923L (W) (W), PVP/VA S-630, PVP/VA E-335, PVP/VA W-930, PVP/VA 923



APPLICATIONS


Povidone K 90 is extensively used in the pharmaceutical industry as a binder in tablet formulations, enhancing tablet cohesion.
In oral care products, such as toothpaste and mouthwashes, Povidone K 90 contributes to product stability and consistency.

The film-forming properties of Povidone K 90 make it valuable in cosmetics, where it is used in formulations like hairsprays.
As a stabilizing agent, Povidone K 90 enhances the quality and shelf life of various topical preparations, including creams and gels.

Povidone K 90 serves as a disintegrant in pharmaceutical tablets, aiding in their quick disintegration for optimal drug absorption.
Povidone K 90 is utilized in the production of fast-dissolving oral films, contributing to the rapid release of medication.
Povidone K 90 is included in certain formulations to improve the bioavailability of poorly water-soluble drugs.

The hygroscopic nature of Povidone K 90 makes it suitable for use in formulations requiring moisture retention.
Different grades of Povidone, such as PVP K30 and PVP K90, are employed in pharmaceutical applications with specific molecular weight requirements.

Povidone K 90 is used in over-the-counter medications due to its pharmaceutical and therapeutic properties.
Povidone K 90 serves as an antiseptic in healthcare and first aid products.
In the production of specialty coatings for pharmaceutical tablets, Povidone ensures uniformity and stability.
Povidone K 90 is found in oral care products, providing benefits such as enhanced texture and improved product consistency.
Its biocompatibility makes Povidone suitable for use in medical devices, wound care products, and surgical applications.

Povidone K 90 is employed in the development of transdermal drug delivery systems to enhance drug absorption through the skin.
Povidone K 90 is used in the food industry as a clarifying agent in the production of beverages.
In the textile industry, PVP is utilized as a dye carrier and for its film-forming properties in sizing agents.

Povidone K 90 is included in the production of contact lens solutions as a lubricating and wetting agent.
Povidone K 90 is employed in the paper industry to improve paper strength and reduce linting.
Povidone K 90 is utilized in hair care products, such as styling gels and mousses, for its film-forming and stabilizing effects.

In the production of adhesives, Povidone K 90 serves as a thickening agent and enhances adhesive properties.
Povidone K 90 is used in the cosmetic industry for its ability to form clear and stable solutions in various formulations.
Povidone K 90 is employed in the production of paints and coatings for its film-forming and dispersing properties.

In the construction industry, Povidone K 90 is used in cement formulations to improve workability and reduce water demand.
Povidone K 90 continues to find applications across various industries due to its versatility, safety, and beneficial properties.

Povidone K 90 is a crucial component in the formulation of veterinary pharmaceuticals, ensuring proper drug delivery and efficacy in animals.
In the production of ophthalmic solutions, PVP is used as a stabilizer to maintain the clarity and stability of the solution.
Povidone K 90 is employed in the manufacturing of wound care products, such as wound dressings and gauze, providing moisture retention and adherence.
The film-forming properties of PVP make it valuable in the production of peel-off masks and skincare patches.

Povidone K 90 is used in the development of transdermal patches to facilitate the controlled release of medications through the skin.
In the printing industry, PVP is utilized as a binder in ink formulations, improving adhesion to various surfaces.
Povidone K 90 is included in the production of instant cold packs, contributing to the gel-like consistency when activated.

Povidone K 90 finds application in the creation of adhesives for various industries, enhancing bonding strength.
Povidone K 90 is utilized in the agricultural sector as a component in crop protection formulations, ensuring uniform distribution of active ingredients.

In the manufacturing of photographic emulsions, Povidone is used as a protective colloid for the dispersion of light-sensitive silver halide crystals.
Povidone K 90 is employed in the development of air fresheners and deodorizing products for its ability to encapsulate and release fragrances.
The cosmetic industry utilizes Povidone in the production of mascara, contributing to the formulation's texture and adherence to lashes.

Povidone K 90 is included in the creation of hair care products like shampoos and conditioners for its conditioning and film-forming properties.
In the production of ceramics, Povidone serves as a binder, contributing to the green strength of molded ceramic articles.

Povidone K 90 is used in the formulation of detergents and cleaning products, improving the stability and viscosity of the solutions.
Povidone K 90 is employed in the manufacturing of biodegradable plastics, enhancing their mechanical properties and processability.
The food industry utilizes PVP as a clarifying agent in the production of beer and wine, aiding in the removal of haze-forming substances.

Povidone K 90 is included in the creation of smoke-generating formulations for firefighting training exercises and signaling devices.
In the textile industry, Povidone is used in dyeing processes as a dye dispersant, improving color uniformity.
Povidone K 90 is employed in the formulation of battery electrolytes, contributing to the stability and performance of the electrolyte solution.
The construction industry utilizes Povidone K 90 in the production of concrete admixtures, improving workability and reducing water demand.

Povidone K 90 is included in the formulation of antifreeze products, aiding in the prevention of scale and corrosion in cooling systems.
In the manufacturing of latex gloves, Povidone is employed as a coating agent to facilitate easy donning and doffing.
Povidone K 90 is utilized in the creation of film coatings for pharmaceutical tablets, providing a protective and aesthetically pleasing layer.
Povidone K 90 continues to find innovative applications across diverse industries, showcasing its adaptability and versatility.

Povidone K 90 is utilized in the formulation of photovoltaic devices to improve the stability and efficiency of perovskite solar cells.
The cosmetic industry employs Povidone in the creation of nail polishes for its film-forming and adhesive properties.
Povidone K 90 is used in the production of inkjet inks to enhance color stability and prevent clogging of printheads.

In the agricultural sector, Povidone is included in seed coatings to improve germination rates and protect seeds from environmental stress.
Povidone K 90 is utilized in the manufacturing of ion exchange resins, contributing to their stability and ion absorption capabilities.

Povidone K 90 is found in the formulation of fuel additives, where it acts as a dispersant to prevent the formation of deposits in engines.
The textile industry uses PVP in sizing agents to improve fiber cohesion and reduce yarn breakage during weaving.
Povidone K 90 is employed in the creation of chromatography resins, aiding in the separation of biomolecules in bioprocessing.

In the production of detergents and laundry products, PVP improves the stability of enzymes and enhances cleaning efficiency.
Povidone K 90 is included in the formulation of wound sealants, providing a protective barrier and promoting tissue adhesion.
The pharmaceutical industry utilizes Povidone in the creation of nasal sprays, ensuring proper drug delivery and absorption.
Povidone K 90 is found in the formulation of oral care products like mouthwash, contributing to its viscosity and stability.

Povidone K 90 is employed in the creation of fuel cell membranes, improving the conductivity and durability of the membranes.
In the paint and coatings industry, PVP is used as a thickening agent, enhancing the viscosity and application properties of coatings.
Povidone K 90 is included in the formulation of lubricating eye drops, providing comfort and moisture to dry eyes.
Povidone K 90 finds application in the creation of anti-fog coatings for eyeglasses and camera lenses.

The semiconductor industry uses PVP in the production of photoresists, facilitating the patterning process in microfabrication.
Povidone K 90 is employed in the formulation of wound care products like adhesive tapes, providing secure and comfortable adhesion.

Povidone K 90 is utilized in the development of hydrogels for medical applications, such as wound dressings and drug delivery systems.
Povidone K 90 is found in the formulation of adhesives for postage stamps, ensuring secure bonding and adhesion to envelopes.
In the creation of antistatic coatings for plastics and textiles, Povidone helps prevent the buildup of static electricity.

Povidone K 90 is used in the formulation of anti-aging skincare products, contributing to the texture and effectiveness of the formulations.
Povidone K 90 finds application in the production of imaging agents for medical diagnostic purposes, improving contrast in imaging techniques.

Povidone K 90 is included in the formulation of specialty inks for screen printing, ensuring durability and adhesion on various surfaces.
Povidone K 90 continues to be explored for emerging applications, showcasing its adaptability and versatility in various industries.



DESCRIPTION


Povidone K 90, also known simply as Povidone or Polyvinylpyrrolidone (PVP), is a polymer that belongs to a group of water-soluble polymers.
Povidone K 90 is a type of polyvinylpyrrolidone with a specific molecular weight range.
Povidone K 90 is widely used in the pharmaceutical, cosmetic, and personal care industries for its various properties.

The chemical structure of Povidone K 90 consists of repeating units of 1-ethenyl-2-pyrrolidinone.
Povidone K 90 is commonly produced by the polymerization of vinylpyrrolidone monomers.
The molecular weight of Povidone can vary, and different grades, such as Povidone K 90, indicate specific molecular weight ranges.
Polyvinylpyrrolidone, commonly known as Povidone or PVP, is a versatile water-soluble polymer.

Povidone K 90 is characterized by its ability to form clear and colorless solutions in water.
Povidone K 90 is derived from the polymerization of vinylpyrrolidone monomers.
Povidone K 90 is widely used in the pharmaceutical industry as a binder in tablet formulations.
Povidone K 90 serves as a stabilizing agent and enhances the consistency of ointments, creams, and gels.

Povidone K 90 exhibits hygroscopic behavior, allowing it to absorb and retain moisture from the environment.
Its film-forming properties make it valuable in various applications requiring a thin, uniform film.
The chemical structure of Povidone consists of repeating units of 1-ethenyl-2-pyrrolidinone.

Povidone K 90 is commonly found in oral care products, contributing to their stability and consistency.
In cosmetics, Povidone K 90 is used in formulations like hair sprays for its film-forming characteristics.
As a disintegrant in pharmaceutical tablets, PVP aids in the quick disintegration of the tablet in the digestive system.

Povidone K 90 has a long history of safe use and is considered biocompatible in various applications.
Povidone K 90 is often included in topical preparations to enhance the overall quality of the product.
Povidone K 90 can be employed as a binder in the production of fast-dissolving oral films.

In the pharmaceutical industry, different grades of Povidone, such as PVP K30 and PVP K90, indicate specific molecular weight ranges.
The solubility of PVP in water allows for easy incorporation into various aqueous formulations.
Povidone K 90 is known for its stabilizing effects in certain formulations, contributing to product shelf life.
Povidone K 90 is part of the excipients used to improve the bioavailability of poorly water-soluble drugs.

Its hygroscopic nature makes Povidone suitable for use in formulations requiring moisture retention.
The polymer is utilized in the production of specialty coatings for pharmaceutical tablets.
Povidone K 90 is found in some over-the-counter medications due to its pharmaceutical and therapeutic properties.

In the production of toothpaste, Povidone contributes to the product's texture and consistency.
Povidone K 90 iodine complex is utilized as an antiseptic in various healthcare and first aid products.
Povidone K 90 plays a crucial role in the pharmaceutical industry, ensuring the effectiveness and stability of drug formulations.
This water-soluble polymer continues to be an essential ingredient in a wide range of pharmaceutical, cosmetic, and personal care applications.



PROPERTIES


Chemical Formula: (C6H9NO)n, where n represents the number of repeating units in the polymer chain.
Molecular Weight: Varies depending on the specific grade of Povidone (e.g., PVP K30, PVP K90).
Chemical Structure: Consists of repeating units of 1-ethenyl-2-pyrrolidinone.
CAS Number: 9003-39-8.
Solubility: Highly soluble in water, forming clear and colorless solutions.
Appearance: Typically white or off-white powder or solid.
Odor: Generally odorless.
Melting Point: Decomposes before reaching a specific melting point.
Boiling Point: Decomposes under high temperatures.
Density: Varies depending on the molecular weight and specific form of Povidone.
pH: PVP solutions are typically neutral.
Hygroscopicity: Exhibits hygroscopic behavior, absorbing and retaining moisture from the environment.



FIRST AID


Inhalation:

If PVP dust or aerosol is inhaled and respiratory discomfort occurs, move the affected person to an area with fresh air.
If breathing difficulties persist, seek medical attention.


Skin Contact:

In case of skin contact, promptly wash the affected area with soap and water.
Remove contaminated clothing and ensure thorough rinsing of the skin.
If irritation or allergic reactions occur, seek medical advice.


Eye Contact:

If PVP comes into contact with the eyes, immediately flush the eyes with gently flowing water for at least 15 minutes, holding the eyelids open.
Seek medical attention if irritation persists or if there is any sign of injury.


Ingestion:

If PVP is ingested accidentally, rinse the mouth with water.
Ingesting PVP is generally not harmful, but seek medical attention if there are concerns or if large amounts are ingested.


General First Aid Measures:

If any adverse reactions, such as skin irritation or respiratory discomfort, occur after exposure to PVP, seek medical assistance promptly.
If seeking medical attention, provide healthcare professionals with details about the specific PVP product and the nature of exposure.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate personal protective equipment, including gloves and safety goggles, when handling Povidone.
Use chemical-resistant gloves to minimize skin contact.

Ventilation:
Work in a well-ventilated area or use local exhaust ventilation to control airborne concentrations.
If handling in an enclosed space, ensure proper ventilation systems are in place.

Avoidance of Contact:
Avoid direct skin and eye contact with Povidone.
Take precautions to prevent inhalation of dust or aerosols.

Handling Procedures:
Follow good manufacturing and laboratory practices when working with Povidone.
Use appropriate tools and equipment to minimize the generation of dust or aerosols.

Spill Response:
In case of a spill, use suitable absorbent materials to contain and clean up the spilled substance.
Dispose of waste according to local regulations.

Storage Compatibility:
Store Povidone away from incompatible materials, such as strong acids, bases, and oxidizing agents.
Check compatibility with storage containers to prevent chemical reactions.

Labeling:
Ensure containers are properly labeled with the correct product information, hazard symbols, and safety precautions.
Maintain clear and visible labeling on secondary containers in case of transfer.


Storage:

Temperature:
Store Povidone in a cool, dry place.
Avoid exposure to extreme temperatures, as excessive heat or cold may affect the stability of the substance.

Container Integrity:
Ensure that storage containers are tightly sealed to prevent contamination or evaporation.
Regularly inspect containers for any signs of damage or leaks.

Ventilation During Storage:
If stored in an enclosed area, provide adequate ventilation to prevent the accumulation of vapors.

Storage Conditions:
Store Povidone in accordance with the manufacturer's recommendations.
Keep the substance away from direct sunlight and incompatible materials.

Separation from Food and Feed:
Store Povidone away from food, beverages, and animal feed.
Use separate storage areas to avoid cross-contamination.

Handling Precautions:
Follow proper handling procedures when transferring Povidone between containers or dispensing it for use.
Minimize the risk of spills during storage and handling.

Fire Prevention:
Povidone is generally not flammable, but it's advisable to keep it away from open flames, sparks, or potential ignition sources.
Store in areas compliant with fire safety regulations.

Emergency Response:
Have appropriate emergency response equipment, such as spill containment materials and fire extinguishers, readily available.
Povidon Iodine
Betadine; Wokadine; Pyodine; Polyvidone Iodine CAS:25655-41-8
POWERCON 100
Powercon 100 IUPAC Name sodium;naphthalene-1-sulfonate Powercon 100 InChI 1S/C10H8O3S.Na/c11-14(12,13)10-7-3-5-8-4-1-2-6-9(8)10;/h1-7H,(H,11,12,13);/q;+1/p-1 Powercon 100 InChI Key HIEHAIZHJZLEPQ-UHFFFAOYSA-M Powercon 100 Canonical SMILES C1=CC=C2C(=C1)C=CC=C2S(=O)(=O)[O-].[Na+] Powercon 100 Molecular Formula C10H7NaO3S Powercon 100 CAS 130-14-3 Powercon 100 Deprecated CAS 1081846-88-9 Powercon 100 European Community (EC) Number 204-976-0 Powercon 100 UNII MAI7V3C3PN Powercon 100 DSSTox Substance ID DTXSID3042394 Powercon 100 Molecular Weight 230.22 g/mol Powercon 100 Hydrogen Bond Donor Count 0 Powercon 100 Hydrogen Bond Acceptor Count 3 Powercon 100 Rotatable Bond Count 1 Powercon 100 Exact Mass 230.00136 g/mol Powercon 100 Monoisotopic Mass 230.00136 g/mol Powercon 100 Topological Polar Surface Area 65.6 Ų Powercon 100 Heavy Atom Count 15 Powercon 100 Formal Charge 0 Powercon 100 Complexity 296 Powercon 100 Isotope Atom Count 0 Powercon 100 Defined Atom Stereocenter Count 0 Powercon 100 Undefined Atom Stereocenter Count 0 Powercon 100 Defined Bond Stereocenter Count 0 Powercon 100 Undefined Bond Stereocenter Count 0 Powercon 100 Covalently-Bonded Unit Count 2 Powercon 100 Compound Is Canonicalized Yes Powercon 100 reduces the viscosity and improve the fluidity of concentrated slurries or solids dispersed in water.Powercon 100, for instance, gives better strength to the concrete with less use of water. These effects are derived from the electrical negative charge that is imparted from PWERCON producing electrostatic repulsive forces to keep the particles separated.Powercon 100 is sodium salt of polymerized naphthalene sulfonic acid.Powercon 100 is cost-effective dispersant, fluidifier and high-range water reducing agent, which exhibits excellent rheological properties especially in concrete and gypsum board.Powercon 100 with its excellent rheological properties is used as the raw material for the admixture of concrete to produce high compressive strength (400~1,000 kg/cm2) concrete and improves the workability for concrete mixture. Concrete admixture with Powercon 100 also reduces the dry shrinkage of concrete without excess bleeding and gives an excellent smooth concrete surface.Powercon 100 was employed as a detection reagent to investigate ion-pair high-performance liquid chromatographic retention behavior of copper(II)-1-oxa-4,7,10,13-tetraazacyclopentadecane complex.[1] It was also employed as a stationary liquid phase for resolution of dichlorophenol isomers by GC.
PPG 10 METHYL GLUCOSE ETHER
PPG-10 Methyl Glucose Ether (also known as Decaglyceryl Monostearate or PEG-10 Methyl Glucose Ether) is an emulsifying and thickening agent used in various cosmetic, personal care, and pharmaceutical products.
PPG 10 Methyl Glucose Ether is derived from natural sources such as corn, wheat, and sugar beets and is commonly used as an alternative to synthetic ingredients.

CAS Number: 61849-72-7



APPLICATIONS


PPG-10 Methyl Glucose Ether is commonly used in personal care products such as shampoos, conditioners, and lotions.
PPG 10 Methyl Glucose Ether can be used as a conditioning agent in hair care products to improve the texture and manageability of hair.

PPG-10 Methyl Glucose Ether can also be used as an emulsifier to stabilize oil-in-water emulsions in personal care products.
PPG 10 Methyl Glucose Ether can improve the spreadability and skin feel of skin care products like creams and lotions.
PPG-10 Methyl Glucose Ether is often used as a viscosity controlling agent to adjust the thickness of personal care products.

PPG 10 Methyl Glucose Ether can also be used as a solubilizer to dissolve lipophilic ingredients in water-based products.
PPG-10 Methyl Glucose Ether can be used in makeup products like foundations, concealers, and lipsticks to improve their texture and application.

PPG 10 Methyl Glucose Ether can improve the skin feel and texture of sunscreens and other UV protection products.
PPG-10 Methyl Glucose Ether can be used as a foaming agent in personal care products like shower gels and bubble baths.

PPG 10 Methyl Glucose Ether is commonly used in baby care products like baby shampoos and lotions due to its gentle and mild nature.
PPG-10 Methyl Glucose Ether can be used in hair styling products like mousses and gels to provide hold and control.

PPG 10 Methyl Glucose Ether can be used in shaving creams and gels to improve the glide of the razor and reduce irritation.
PPG-10 Methyl Glucose Ether is often used in bath products like bath oils and salts to improve the emulsion stability and skin feel.

PPG 10 Methyl Glucose Ether can be used in deodorant and antiperspirant products to improve the spreadability and skin feel.
PPG-10 Methyl Glucose Ether can also be used as a fragrance ingredient to enhance the scent of personal care products.
PPG 10 Methyl Glucose Ether is commonly used in facial cleansers and scrubs to provide mild exfoliation and improve the skin feel.

PPG-10 Methyl Glucose Ether can be used in hand sanitizers and other disinfecting products as a viscosity controlling agent.
PPG 10 Methyl Glucose Ether can be used in foot care products like creams and scrubs to improve the texture and soften calluses.

PPG-10 Methyl Glucose Ether can be used in after-sun care products like gels and lotions to soothe and hydrate sunburned skin.
PPG 10 Methyl Glucose Ether can be used in hair removal products like depilatory creams and lotions to improve the spreadability and skin feel.

PPG-10 Methyl Glucose Ether can be used in dental care products like toothpaste and mouthwash to improve the texture and mouthfeel.
PPG 10 Methyl Glucose Ether can be used in pet care products like shampoos and conditioners to improve the texture and shine of the fur.

PPG-10 Methyl Glucose Ether can be used in massage oils and lotions to improve the glide and spreadability.
PPG 10 Methyl Glucose Ether can be used in personal lubricants to improve the texture and reduce irritation.
PPG-10 Methyl Glucose Ether can be used in wound care products like hydrogels and dressings to improve the wound healing process.


PPG-10 Methyl Glucose Ether has various applications in different industries.
Some of the common applications of PPG-10 Methyl Glucose Ether are:

Personal care products:

PPG-10 Methyl Glucose Ether is used as a thickening agent in personal care products such as shampoos, conditioners, shower gels, and facial cleansers.


Cosmetics:

PPG 10 Methyl Glucose Ether is used as an emulsifier and stabilizer in cosmetics such as lotions, creams, and makeup products.


Cleaning products:

PPG-10 Methyl Glucose Ether is used as a surfactant in cleaning products such as laundry detergents and dishwashing liquids.


Textile industry:

PPG 10 Methyl Glucose Ether is used as a finishing agent for textiles to improve the texture and feel of the fabric.


Adhesives:

PPG-10 Methyl Glucose Ether is used as a binding agent in adhesives.


Agriculture:

PPG 10 Methyl Glucose Ether is used in pesticides and insecticides as a surfactant to improve the effectiveness of the active ingredients.


Paints and coatings:

PPG-10 Methyl Glucose Ether is used as a thickening and dispersing agent in paints and coatings.


Paper industry:

PPG 10 Methyl Glucose Ether is used in the paper industry as a coating agent to improve the paper's quality and texture.


Food industry:

PPG-10 Methyl Glucose Ether is used in the food industry as a thickening and stabilizing agent in products such as salad dressings and sauces.


Pharmaceuticals:

PPG 10 Methyl Glucose Ether is used in the pharmaceutical industry as a solubilizer and emulsifier for active ingredients in various drug formulations.


Water treatment:

PPG-10 Methyl Glucose Ether is used in water treatment as a coagulant to remove impurities and improve the water quality.


Oil and gas industry:

PPG 10 Methyl Glucose Ether is used in the oil and gas industry as a demulsifier to separate oil and water.


Rubber industry:

PPG-10 Methyl Glucose Ether is used in the rubber industry as a plasticizer and softening agent.


Metalworking:

PPG 10 Methyl Glucose Ether is used in metalworking as a lubricant and cooling agent.


Construction industry:

PPG-10 Methyl Glucose Ether is used in the construction industry as a plasticizer for concrete and as a binder for gypsum products.


PPG-10 Methyl Glucose Ether is widely used in personal care products as a thickener and emulsifier.
PPG 10 Methyl Glucose Ether is commonly used in hair care products, such as shampoos and conditioners, to provide a smooth texture and improve hair manageability.

PPG-10 Methyl Glucose Ether can also be used in skincare products, such as moisturizers and lotions, to provide a soft and silky texture to the skin.
PPG 10 Methyl Glucose Ether is used in many cosmetic formulations, including makeup products like foundations, primers, and concealers, to improve the texture and spreadability.
In oral care products, such as toothpaste, PPG-10 Methyl Glucose Ether is used to improve the thickness and texture of the product.

PPG 10 Methyl Glucose Ether is also used in deodorants and antiperspirants to improve the texture and provide a smooth application.
PPG-10 Methyl Glucose Ether is used in sun care products to help provide water resistance and improve the texture of the product.

PPG 10 Methyl Glucose Ether is used in baby care products, such as baby wipes, to provide a soft and gentle texture.
PPG-10 Methyl Glucose Ether is used in pharmaceutical formulations as a binder and disintegrant.
PPG 10 Methyl Glucose Ether can be used in pet care products, such as shampoos and conditioners, to provide a soft and silky texture to the animal's fur.

In household cleaning products, such as laundry detergents, PPG-10 Methyl Glucose Ether is used as a thickener and stabilizer.
PPG 10 Methyl Glucose Ether is used in industrial cleaning products, such as degreasers and solvent cleaners, to help improve the viscosity and stability of the product.

PPG-10 Methyl Glucose Ether is used in agricultural formulations as a surfactant and emulsifier.
PPG 10 Methyl Glucose Ether can be used in the food industry as a stabilizer and thickener.
In the paper and pulp industry, PPG-10 Methyl Glucose Ether is used as a wetting agent and dispersant.

PPG 10 Methyl Glucose Ether is used in adhesives and sealants to provide a smooth texture and improve adhesion.
PPG-10 Methyl Glucose Ether is used in textile processing as a thickener and stabilizer.
PPG 10 Methyl Glucose Ether can be used in the rubber industry as a processing aid and dispersant.

In the construction industry, PPG 10 Methyl Glucose Ether is used as an additive in cement and concrete to improve the workability and strength.
PPG-10 Methyl Glucose Ether is used in oil and gas drilling fluids as a rheology modifier and emulsifier.

PPG 10 Methyl Glucose Ether is used in the manufacturing of paints and coatings to improve the texture and flow properties.
PPG 10 Methyl Glucose Ether is used in the electronics industry as a cleaning agent and as an additive in soldering fluxes.

PPG-10 Methyl Glucose Ether is used in the mining industry as a flotation agent and dispersant.
PPG 10 Methyl Glucose Ether can be used in the water treatment industry as a flocculant and coagulant aid.
In the printing industry, PPG-10 Methyl Glucose Ether is used as a dispersant and thickener for inks and coatings.

PPG 10 Methyl Glucose Ether is used in the manufacturing of ceramics as a binding agent and dispersant.
PPG-10 Methyl Glucose Ether is used in the production of detergents as a thickener and stabilizer.

PPG 10 Methyl Glucose Ether can be used in the manufacturing of fragrances and flavors as a carrier and stabilizer.
PPG-10 Methyl Glucose Ether is commonly used in skin care products such as lotions and creams to provide a silky feel.

PPG 10 Methyl Glucose Ether is often used in hair care products such as shampoos and conditioners to improve their texture and feel.
PPG-10 Methyl Glucose Ether can also be found in shaving products like gels and creams to improve their texture.

PPG 10 Methyl Glucose Ether is a popular ingredient in baby care products such as baby wipes, creams, and lotions due to its mild and gentle nature.
PPG-10 Methyl Glucose Ether is used in sun care products such as sunscreens and after-sun lotions to enhance the skin feel.
PPG 10 Methyl Glucose Ether can also be found in facial cleansers and masks to help improve the texture of the product.

PPG-10 Methyl Glucose Ether is used in deodorants and antiperspirants to improve the texture and skin feel of the product.
PPG 10 Methyl Glucose Ether is commonly used in body washes and shower gels to provide a smooth and silky feel to the skin.

PPG-10 Methyl Glucose Ether can be found in toothpaste and mouthwash products to improve the texture of the product.
PPG 10 Methyl Glucose Ether is often used in hand sanitizers and antibacterial products to help improve the skin feel and texture.

PPG-10 Methyl Glucose Ether is used in makeup products such as foundations and powders to enhance the texture and application of the product.
PPG 10 Methyl Glucose Ether is commonly used in hair styling products such as gels, mousses, and sprays to enhance the texture and hold of the product.
PPG-10 Methyl Glucose Ether can be found in lip care products such as lip balms and lipsticks to improve the texture and feel of the product.

PPG 10 Methyl Glucose Ether is commonly used in wound care products such as dressings and ointments to enhance the texture and application of the product.
PPG-10 Methyl Glucose Ether can be found in pet care products such as shampoos and conditioners to improve the texture and feel of the product.

PPG 10 Methyl Glucose Ether is commonly used in cleaning products such as soaps and detergents to improve the texture and cleaning properties of the product.
PPG-10 Methyl Glucose Ether is used in fragrance products such as perfumes and colognes to enhance the texture and application of the product.

PPG 10 Methyl Glucose Ether can be found in food products such as dressings, sauces, and baked goods as a texture and viscosity enhancer.
PPG-10 Methyl Glucose Ether is used in agricultural products such as herbicides and insecticides to improve the texture and application of the product.

PPG 10 Methyl Glucose Ether is commonly used in automotive products such as lubricants and fuel additives to improve the texture and viscosity of the product.
PPG-10 Methyl Glucose Ether can be found in industrial products such as adhesives and coatings as a viscosity and texture enhancer.
PPG 10 Methyl Glucose Ether is used in textile products such as fabric softeners and laundry detergents to improve the texture and feel of the product.

PPG-10 Methyl Glucose Ether can be found in paint and coating products to improve the viscosity and texture of the product.
PPG 10 Methyl Glucose Ether is used in construction products such as concrete and mortar as a viscosity enhancer.
PPG-10 Methyl Glucose Ether can be found in personal lubricant products to enhance the texture and feel of the product.



DESCRIPTION


PPG-10 Methyl Glucose Ether (also known as Decaglyceryl Monostearate or PEG-10 Methyl Glucose Ether) is an emulsifying and thickening agent used in various cosmetic, personal care, and pharmaceutical products.
PPG 10 Methyl Glucose Ether is derived from natural sources such as corn, wheat, and sugar beets and is commonly used as an alternative to synthetic ingredients.

PPG-10 Methyl Glucose Ether is a glyceryl ether of methylglucoside that has a molecular weight of approximately 540 g/mol.
PPG 10 Methyl Glucose Ether is a yellowish-white powder that is soluble in water and ethanol.

The primary function of PPG-10 Methyl Glucose Ether is to act as an emulsifier, which helps to mix oil and water-based ingredients in a product.
PPG 10 Methyl Glucose Ether also serves as a thickening agent and helps to improve the texture and consistency of the product.

In addition to its emulsifying and thickening properties, PPG-10 Methyl Glucose Ether also has moisturizing properties that can help to improve the hydration and overall health of the skin.
PPG-10 Methyl Glucose Ether is commonly used in various cosmetic and personal care products such as lotions, creams, gels, and shampoos.
PPG 10 Methyl Glucose Ether is also used in some pharmaceutical products as an excipient.

As a natural and biodegradable ingredient, PPG-10 Methyl Glucose Ether is considered safe for use in cosmetic and personal care products.
PPG 10 Methyl Glucose Ether is generally well-tolerated by the skin and does not cause any significant side effects.

PPG-10 Methyl Glucose Ether (MG-10) is a non-ionic, water-soluble polymer that belongs to the family of alkyl polyglucosides.
PPG 10 Methyl Glucose Ether is a clear to slightly hazy liquid with a mild odor and is commonly used as a viscosity builder, emulsifier, and skin conditioning agent in various personal care and cosmetic products.


Some of the key properties of PPG-10 Methyl Glucose Ether are:

Water solubility:
PPG 10 Methyl Glucose Ether is highly water-soluble and can dissolve in both hot and cold water.

Viscosity:
PPG 10 Methyl Glucose Ether has the ability to increase the viscosity of aqueous solutions and form gels.

Stability:
PPG 10 Methyl Glucose Ether is stable over a wide range of pH levels and temperatures, making it suitable for use in a variety of formulations.

Emulsification:
PPG 10 Methyl Glucose Ether can emulsify oils and other hydrophobic ingredients in water-based systems.

Mildness:
PPG 10 Methyl Glucose Ether is gentle on the skin and eyes and is considered to be non-irritating and non-sensitizing.

Biodegradability:
PPG 10 Methyl Glucose Ether is readily biodegradable, which makes it an environmentally friendly ingredient.

Compatibility:
PPG 10 Methyl Glucose Ether is compatible with a wide range of other cosmetic ingredients, including surfactants, thickeners, and preservatives.


Overall, PPG-10 Methyl Glucose Ether is a versatile and multifunctional ingredient that offers several benefits in personal care and cosmetic formulations.



PROPERTIES


Chemical formula: C19H38O10
Molecular weight: 430.5 g/mol
Appearance: Clear to slightly hazy, viscous liquid
Solubility: Soluble in water and ethanol, insoluble in oils and hydrocarbons
pH: 5.5 - 7.5
Density: 1.11 g/cm³
Viscosity: 2500 - 7000 cP
Hydroxyl value: 180 - 230 mg KOH/g
Flash point: > 100°C (closed cup)
Boiling point: Decomposes before boiling


Note that these values can vary depending on the specific grade and manufacturer of PPG-10 Methyl Glucose Ether.



FIRST AID


Inhalation:

Remove the person to a well-ventilated area.
If the person is not breathing, administer artificial respiration.
Seek medical attention immediately.


Skin Contact:

Remove contaminated clothing and rinse affected skin with plenty of water for at least 15 minutes.
If skin irritation persists, seek medical attention.


Eye Contact:

Rinse eyes thoroughly with water for at least 15 minutes while holding eyelids open.
Remove contact lenses, if present and easy to do so, and continue rinsing.
Seek medical attention if eye irritation persists.


Ingestion:

Do not induce vomiting unless directed to do so by medical personnel.
Rinse mouth thoroughly with water and drink plenty of water if conscious.
Seek medical attention immediately.


Notes to Physician:

Treatment should be based on the symptoms of the patient and on the severity of the exposure.
No specific antidote is available.
In case of ingestion, gastric lavage may be considered if the amount ingested is potentially life-threatening.
Treat symptomatically.



HANDLING AND STORAGE


Handling:

Avoid prolonged or repeated skin contact. Wear protective gloves and clothing when handling the material.
Use in a well-ventilated area to avoid inhalation of vapor or mist.
Avoid contact with eyes, as it may cause irritation.

In case of eye contact, rinse thoroughly with water for at least 15 minutes and seek medical attention if necessary.
Avoid ingestion.
If swallowed, do not induce vomiting and seek medical attention immediately.


Storage:

Store in a cool, dry, and well-ventilated area away from sources of heat and ignition.
Keep container tightly closed when not in use.
Store away from incompatible materials such as strong acids, bases, and oxidizing agents.
Do not store near food or beverages.

Store in a designated area with proper labeling and keep out of reach of children and unauthorized personnel.
Ensure that storage area is equipped with appropriate fire-fighting equipment and spill-containment materials.
Keep the material away from direct sunlight, ultraviolet radiation, and extreme temperatures.



SYNONYMS


Methyl Gluceth-10
Methyl Glucose Ether-10
PPG-10 Methyl Glucose Ether
PPG-10 Methyl Glucoside
Methyl Glucoside Polypropylene Glycol Ether
Polypropylene Glycol 10 Methyl Glucose Ether
Methyl Glucose Polypropylene Glycol Ether 10
Methyl Gluceth-10 Ether
Poly(oxy-1,2-ethanediyl), .alpha.-(2-(methyl-1-oxo-2-propenyl)oxy)-.omega.-((2-
(((2-(methyl-1-oxo-2-propenyl)oxy)ethoxy)carbonyl)amino)ethoxy)-
2-Propenoic acid, 2-methyl-, methyl ester, polymer with ethylene glycol monomethyl ether and 1,2,3-propanetriol
Methyl Glucose Ether
Methyl Glucoside
Methyl Gluceth
Methyl Gluceth-10
PEG-10 Methyl Glucose Ether
PEG-10 Methyl Gluceth
PEG-10 Methyl Gluceth-10
Gluceth-10
Gluceth-10 Methacrylate Crosspolymer
Gluceth-10 Laurate
Gluceth-10 Stearate
Gluceth-10 Acetate
Gluceth-10 Hydroxypropyl Dimonium Chloride
Gluceth-10 PEG-75 Lanolin Oil
Gluceth-10 Tristearate
Gluceth-10 Cocoate
Gluceth-10 Isostearate
Gluceth-10 Methacrylate
Gluceth-10 Phosphate
Gluceth-10 Sesquistearate
Gluceth-10 Trioleate
Gluceth-10 Behenate
Gluceth-10 Dioleate
Gluceth-10 Laurate/Myristate
Gluceth-10 Methacrylate/Styrene Crosspolymer
Gluceth-10 Triisostearate
Methyl Gluceth-20
Methyl Gluceth-21
Methyl Gluceth-25
Methyl Gluceth-6.5 Triacetate
Methyl Gluceth-10
Poly(oxy-1,2-ethanediyl), alpha-(2-methylglucosyl)-omega-hydroxy-
2-Methylglucoside, polymer with ethylene oxide
Methyl gluceth-10 acetate
PPG-10 Methyl Glucose Ether Acetate
Methyl glucoside-10 acetate
Polyethylene glycol methyl glucose ether
Methyl gluceth-10 benzoate
PPG-10 Methyl Glucose Ether Benzoate
Methyl Gluceth-10 succinate
Poly(oxy-1,2-ethanediyl), α-(2-methylglucosyl)-ω-(octyloxy)-
Methyl Gluceth-10 hydroxypropyltrimonium chloride
PPG-10 Methyl Glucose Ether Laurate
Methyl Gluceth-10 lactate
Poly(oxy-1,2-ethanediyl), α-(2-methylglucosyl)-ω-hydroxy-, C10-16 alkyl ethers
PPG-10 Methyl Glucose Ether Oleate
Methyl gluceth-10 palmitate
PPG-10 Methyl Glucose Ether Palmitate
Methyl gluceth-10 stearate
PPG-10 Methyl Glucose Ether Stearate
PPG 2000  (POLI PROPILEN GLIKOL 2000)
Polypropylene glycol 4000; Methylethyl glycol; Methylethylene glycol; 1,2-Propanediol; alpha-Propylene glycol; Methyl glycol; Monopropylene glycol; PG; 1,2-Dihydroxypropane; 1,2-Propylene Glycol; 2-Hydroxypropanol; 2,3-Propanediol; Propane-1,2-diol; Trimethyl glycol; 1,2-Propylenglykol; Isopropylene glycol; cas no: 25322-69-4
PPG 4000
PPG 4000 PPG 4000 is clear, colorless, slightly syrupy liquid at room temperature. It may exist in air in the vapor form, although PPG 4000 must be heated or briskly shaken to produce a vapor. PPG 4000 is practically odorless and tasteless. PPG-4000 is a bifunctional polyether polyol. Suitable for the production of polyurethane adhesives. Shelf life of ARCOL POLYOL PPG-4000 is 12 months. What is PPG 4000? PPG 4000 is a synthetic liquid substance that absorbs water. PPG 4000 is also used to make polyester compounds, and as a base for deicing solutions. PPG 4000 is used by the chemical, food, and pharmaceutical industries as an antifreeze when leakage might lead to contact with food. The Food and Drug Administration (FDA) has classified PPG 4000 as an additive that is "generally recognized as safe" for use in food. It is used to absorb extra water and maintain moisture in certain medicines, cosmetics, or food products. It is a solvent for food colors and flavors, and in the paint and plastics industries. PPG 4000 is also used to create artificial smoke or fog used in fire-fighting training and in theatrical productions. Other names for PPG 4000 are 1,2-dihydroxypropane, 1,2-propanediol, methyl glycol, and trimethyl glycol. Laboratory S-Propanediol is synthesized from via fermentation methods. Lactic acid and lactaldehyde are common intermediates. Dihydroxyacetone phosphate, one of the two products of breakdown (glycolysis) of fructose 1,6-bisphosphate, is a precursor to methylglyoxal. This conversion is the basis of a potential biotechnological route to the commodity chemical 1,2-propanediol. Three-carbon deoxysugars are also precursor to the 1,2-diol.[4] Applications Polymers Forty-five percent of PPG 4000 produced is used as a chemical feedstock for the production of unsaturated polyester resins. In this regard, PPG 4000 reacts with a mixture of unsaturated maleic anhydride and isophthalic acid to give a copolymer. This partially unsaturated polymer undergoes further crosslinking to yield thermoset plastics. Related to this application, PPG 4000 reacts with propylene oxide to give oligomers and polymers that are used to produce polyurethanes.[4] PPG 4000 is used in waterbased acrylic architectural paints to extend dry time which it accomplishes by preventing the surface from drying due to its slower evaporation rate compared to water. Food PPG 4000 is also used in various edible items such as coffee-based drinks, liquid sweeteners, ice cream, whipped dairy products and soda. Vaporizers used for delivery of pharmaceuticals or personal-care products often include PPG 4000 among the ingredients. In alcohol-based hand sanitizers, it is used as a humectant to prevent the skin from drying.[11] PPG 4000 is used as a solvent in many pharmaceuticals, including oral, injectable, and topical formulations. Many pharmaceutical drugs which are insoluble in water utilize PPG 4000 as a solvent and carrier; benzodiazepine tablets are one example.[12] PPG 4000 is also used as a solvent and carrier for many pharmaceutical capsule preparations. Additionally, certain formulations of artificial tears use proplyene glycol as an ingredient. PPG 4000 is commonly used to de-ice aircraft Antifreeze The freezing point of water is depressed when mixed with PPG 4000. It is used as aircraft de-icing fluid.[4][14] Water-PPG 4000 mixtures dyed pink to indicate the mixture is relatively nontoxic are sold under the name of RV or marine antifreeze. PPG 4000 is frequently used as a substitute for ethylene glycol in low toxicity, environmentally friendly automotive antifreeze. It is also used to winterize the plumbing systems in vacant structures.[15] The eutectic composition/temperature is 60:40 PPG 4000:water/-60 °C. The −50 °F/−45 °C commercial product is, however, water rich; a typical formulation is 40:60.[18] Electronic cigarettes liquid PPG 4000 is often used in electronic cigarettes. Along with vegetable glycerin as the main ingredient (<1–92%) in e-liquid used in electronic cigarettes, where it is aerosolized to resemble smoke. It serves as both the carrier for substances like nicotine and cannabinoids, as well as for creating a vapor which resembles smoke. FEATURES May also be included as a component in other urethane products & applications. Coatings Adhesives Sealants Elastomers Polypropylene glycols are liquids, mostly insoluble in water, used to suppress foaming in industrial processes and for making polyurethane resins, hydraulic fluids, and various other materials. PPG 4000 or polypropylene oxide is the polymer of propylene glycol. Chemically it is a polyether, and, more generally speaking, it's a polyalkylene glycol (PAG). The term PPG 4000 or PPG 4000 is reserved for low to medium range molar mass polymer when the nature of the end-group, which is usually a hydroxyl group, still matters. The term "oxide" is used for high molar mass polymer when end-groups no longer affect polymer properties. In 2003, 60% of the annual production of propylene oxide of 6.6×106 tonnes was converted into the polymer. Miscellaneous applications A bottle of flavored e-liquid for vaping shows PPG 4000 as one of the main ingredients along with vegetable glycerin. PPG 4000 (often abbreviated 'PPG') has many applications. Some common applications see PPG 4000 used: As a solvent for many substances, both natural and synthetic. As a humectant (E1520). As a freezing point depressant for slurry ice. In veterinary medicine as an oral treatment for hyperketonaemia in ruminants. In the cosmetics industry, where PPG 4000 is very commonly used as a carrier or base for various types of makeup. For trapping and preserving insects (including as a DNA preservative).[23] For the creation of theatrical smoke and fog in special effects for film and live entertainment. So-called 'smoke machines' or 'hazers' vaporize a mixture of PPG 4000 and water to create the illusion of smoke. While many of these machines use a PPG 4000-based fuel, some use oil. Those which use PPG 4000 do so in a process that is identical to how electronic cigarettes work; utilizing a heating element to produce a dense vapor. The vapor produced by these machines has the aesthetic look and appeal of smoke, but without exposing performers and stage crew to the harms and odors associated with actual smoke. As an additive in PCR to reduce the melting temperature of nucleic acids for targeting of GC rich sequences. 1.2 What happens to PPG 4000 when it enters the environment? Waste streams from the manufacture of PPG 4000 are primarily responsible for the releases into the air, water, and soil. PPG 4000 can enter the environment when it is used as a runway and aircraft de-icing agent. PPG 4000 can also enter the environment through the disposal of products that contains it. It is not likely to exist in large amounts in the air. We have little information about what happens to PPG 4000 in the air. The small amounts that may enter the air are likely to break down quickly. If it escapes into the air, it will take between 24 and 50 hours for half the amount released to break down. PPG 4000 can mix completely with water and can soak into soil. It can break down relatively quickly (within several days to a week) in surface water and in soil. PPG 4000 can also travel from certain types of food packages into the food in the package. 1.3 How might I be exposed to PPG 4000? PPG 4000 has been approved for use at certain levels in food, cosmetics, and pharmaceutical products. If you eat food products, use cosmetics, or take medicines that contain it, you will be exposed to PPG 4000, but these amounts are not generally considered harmful. People who work in industries that use PPG 4000 may be exposed by touching these products or inhaling mists from spraying them. These exposures tend to be at low levels, however. PPG 4000 is used to make artificial smoke and mists for fire safety training, theatrical performances, and rock concerts. These artificial smoke products may also be used by private citizens. These products are frequently used in enclosed spaces, where exposure may be more intense. 1.4 How can PPG 4000 ether enter and leave my body? PPG 4000 can enter your bloodstream if you breathe air containing mists or vapors from this compound. It can also enter your bloodstream through your skin if you come in direct contact with it and do not wash it off. If you eat products that contain PPG 4000, it may enter your bloodstream. Exposure of the general population to PPG 4000 is likely since many foods, drugs, and cosmetics contain it. PPG 4000 breaks down in the body in about 48 hours. However, studies of people and animals show that if you have repeated eye, skin, nasal, or oral exposures to PPG 4000 for a short time, you may develop some irritation. 1.5 How can PPG 4000 affect my health? PPG 4000 breaks down at the same rate as ethylene glycol, although it does not form harmful crystals when it breaks down. Frequent skin exposure to PPG 4000 can sometimes irritate the skin. 1.6 Is there a medical test to determine whether I have been exposed to PPG 4000? PPG 4000 is generally considered to be a safe chemical, and is not routinely tested for, unless specific exposure, such as to a medicine or cosmetic, can be linked with the observed bad symptoms. Since PPG 4000 breaks down very quickly in the body, it is very difficult to detect. 1.7 What recommendations has the federal government made to protect human health? The government has developed regulations and guidelines for PPG 4000. These are designed to protect the public from potential adverse health effects. The Food and Drug Administration (FDA) has classified PPG 4000 as "generally recognized as safe," which means that it is acceptable for use in flavorings, drugs, and cosmetics, and as a direct food additive. According to the World Health Organization, the acceptable dietary intake of PPG 4000 is 25 mg of PPG 4000 for every kilogram (kg) of body weight. Polymerization PPG 4000 is produced by ring-opening polymerization of propylene oxide. The initiator is an alcohol and the catalyst a base, usually potassium hydroxide. When the initiator is ethylene glycol or water the polymer is linear. With a multifunctional initiator like glycerine, pentaerythritol or sorbitol the polymer branches out. PPG 4000 Conventional polymerization of propylene oxide results in an atactic polymer. The isotactic polymer can be produced from optically active propylene oxide, but at a high cost. A salen cobalt catalyst was reported in 2005 to provide isotactic polymerization of the prochiral propylene oxide[2] Cobalt catalyst for isotactic polypropylene oxide Properties PPG 4000 has many properties in common with polyethylene glycol. The polymer is a liquid at room temperature. Solubility in water decreases rapidly with increasing molar mass. Secondary hydroxyl groups in PPG 4000 are less reactive than primary hydroxyl groups in polyethylene glycol. PPG 4000 is less toxic than PEG, so biotechnologicals are now produced in PPG 4000. PPG 4000 (IUPAC name: propane-1,2-diol) is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. Its chemical formula is CH3CH(OH)CH2OH. Containing two alcohol groups, it is classed as a diol. It is miscible with a broad range of solvents, including water, acetone, and chloroform. In general, glycols are non-irritating and have very low volatility. It is produced on a large scale primarily for the production of polymers. In the European Union, it has E-number E1520 for food applications. For cosmetics and pharmacology, the number is E490. PPG 4000 is also present in PPG 4000 alginate, which is known as E405. PPG 4000 is a compound which is GRAS (generally recognized as safe) by the US FDA (Food and Drug Administration) under 21 CFR x184.1666, and is also approved by the FDA for certain uses as an indirect food additive. PPG 4000 is approved and used as a vehicle for topical, oral, and some intravenous pharmaceutical preparations in the U.S. and in Europe. Structure The compound is sometimes called (alpha) α-PPG 4000 to distinguish it from the isomer propane-1,3-diol, known as (beta) β-PPG 4000. PPG 4000 is chiral. Commercial processes typically use the racemate. The S-isomer is produced by biotechnological routes. Production Industrial Industrially, PPG 4000 is mainly produced from propylene oxide (for food-grade use). According to a 2018 source, 2.16 M tonnes are produced annually.[4] Manufacturers use either non-catalytic high-temperature process at 200 °C (392 °F) to 220 °C (428 °F), or a catalytic method, which proceeds at 150 °C (302 °F) to 180 °C (356 °F) in the presence of ion exchange resin or a small amount of sulfuric acid or alkali. Final products contain 20% PPG 4000, 1.5% of diPPG 4000, and small amounts of other polyPPG 4000s.[6] Further purification produces finished industrial grade or USP/JP/EP/BP grade PPG 4000 that is typically 99.5% or greater. Use of USP (US Pharmacopoeia) PPG 4000 can reduce the risk of Abbreviated New Drug Application (ANDA) rejection.[7] PPG 4000 can also be obtained from glycerol, a byproduct from the production of biodiesel.[4] This starting material is usually reserved for industrial use because of the noticeable odor and taste that accompanies the final product. Safety in humans When used in average quantities, PPG 4000 has no measurable effect on development and/or reproduction on animals and probably does not adversely affect human development or reproduction.[26] The safety of electronic cigarettes—which utilize PPG 4000-based preparations of nicotine or THC and other cannabinoids—is the subject of much controversy.- Oral administration The acute oral toxicity of PPG 4000 is very low, and large quantities are required to cause perceptible health effects in humans; in fact, PPG 4000 is three times less toxic than ethanol.[30] PPG 4000 is metabolized in the human body into pyruvic acid (a normal part of the glucose-metabolism process, readily converted to energy), acetic acid (handled by ethanol-metabolism), lactic acid (a normal acid generally abundant during digestion),[31] and propionaldehyde (a potentially hazardous substance). According to the Dow Chemical Company, The LD50 (Lethal Dose that kills in 50% of tests) for rats is 20 g/kg (rat/oral). Toxicity generally occurs at plasma concentrations over 4 g/L, which requires extremely high intake over a relatively short period of time, or when used as a vehicle for drugs or vitamins given intravenously or orally in large bolus doses.[37] It would be nearly impossible to reach toxic levels by consuming foods or supplements, which contain at most 1 g/kg of PPG 4000, except for alcoholic beverages in the US which are allowed 5 percent = 50g/kg.[38] Cases of PPG 4000 poisoning are usually related to either inappropriate intravenous administration or accidental ingestion of large quantities by children. The potential for long-term oral toxicity is also low. In an NTP continuous breeding study, no effects on fertility were observed in male or female mice that received PPG 4000 in drinking water at doses up to 10,100 mg/kg bw/day. No effects on fertility were seen in either the first or second generation of treated mice.[26] In a 2-year study, 12 rats were provided with feed containing as much as 5% PPG 4000, and showed no apparent ill effects.[40] Because of its low chronic oral toxicity, PPG 4000 was classified by the U. S. Food and Drug Administration as "generally recognized as safe" (GRAS) for use as a direct food additive, including frozen foods such as ice cream and frozen desserts. The GRAS designation is specific to its use in food, and does not apply to other uses. Skin, eye and inhalation contact PPG 4000 is essentially non-irritating to the skin.[43] Undiluted PPG 4000 is minimally irritating to the eye, producing slight transient conjunctivitis; the eye recovers after the exposure is removed. A 2018 human volunteer study found that 10 male and female subjects undergoing 4 hours exposures to concentrations of up to 442 mg/m3 and 30 minutes exposures to concentrations of up to 871 mg/m3 in combination with moderate exercise did not show pulmonary function deficits, or signs of ocular irritation, with only slight symptoms of respiratory irritation reported.[44] Inhalation of PPG 4000 vapors appears to present no significant hazard in ordinary applications.[45] Due to the lack of chronic inhalation data, it is recommended that PPG 4000 not be used in inhalation applications such as theatrical productions, or antifreeze solutions for emergency eye wash stations.[46] Recently, PPG 4000 (commonly alongside glycerol) has been included as a carrier for nicotine and other additives in e-cigarette liquids, the use of which presents a novel form of exposure. The potential hazards of chronic inhalation of PPG 4000 or the latter substance as a whole are as-yet unknown. According to a 2010 study, the concentrations of PPG 4000Es (counted as the sum of PPG 4000 and glycol ethers) in indoor air, particularly bedroom air, has been linked to increased risk of developing numerous respiratory and immune disorders in children, including asthma, hay fever, eczema, and allergies, with increased risk ranging from 50% to 180%. This concentration has been linked to use of water-based paints and water-based system cleansers. However, the study authors write that glycol ethers and not PPG 4000 are the likely culprit. PPG 4000 has not caused sensitization or carcinogenicity in laboratory animal studies, nor has it demonstrated genotoxic potential. Intravenous administration Studies with intravenously administered PPG 4000 have resulted in LD50 values in rats and rabbits of 7 mL/kg BW.[53] Ruddick (1972) also summarized intramuscular LD50 data for rat as 13-20 mL/kg BW, and 6 mL/kg BW for the rabbit. Adverse effects to intravenous administration of drugs that use PPG 4000 as an excipient have been seen in a number of people, particularly with large bolus dosages. Responses may include CNS depression, "hypotension, bradycardia, QRS and T abnormalities on the ECG, arrhythmia, cardiac arrhythmias, seizures, agitation, serum hyperosmolality, lactic acidosis, and haemolysis".[54] A high percentage (12% to 42%) of directly-injected PPG 4000 is eliminated or secreted in urine unaltered depending on dosage, with the remainder appearing in its glucuronide-form. The speed of renal filtration decreases as dosage increases,[55] which may be due to PPG 4000's mild anesthetic / CNS-depressant -properties as an alcohol.[56] In one case, intravenous administration of PPG 4000-suspended nitroglycerin to an elderly man may have induced coma and acidosis.[57] However, no confirmed lethality from PPG 4000 was reported. Animals PPG 4000 is an approved food additive for dog and sugar glider food under the category of animal feed and is generally recognized as safe for dogs,[58] with an LD50 of 9 mL/kg. The LD50 is higher for most laboratory animals (20 mL/kg).[59] However, it is prohibited for use in food for cats due to links to Heinz body formation and a reduced lifespan of red blood cells.[60] Heinz body formation from MPPG 4000 has not been observed in dogs, cattle, or humans. Environmental PPG 4000 occurs naturally, probably as the result of anaerobic catabolism of sugars in the human gut. It is degraded by vitamin B12-dependent enzymes, which convert it to propionaldehyde.[68] PPG 4000 is expected to degrade rapidly in water from biological processes, but is not expected to be significantly influenced by hydrolysis, oxidation, volatilization, bioconcentration, or adsorption to sediment.[69] PPG 4000 is readily biodegradable under aerobic conditions in freshwater, in seawater and in soil. Therefore, PPG 4000 is considered as not persistent in the environment. PPG 4000 exhibits a low degree of toxicity toward aquatic organisms. Several guideline studies available for freshwater fish with the lowest observed effect concentration of 96-h LC50 value of 40,613 mg/l in a study with Oncorhynchus mykiss. Similarly, the effect concentration determined in marine fish is a 96-h LC50 of >10,000 mg/l in Scophthalmus maximus. Allergic reaction Estimates on the prevalence of PPG 4000 allergy range from 0.8% (10% PPG 4000 in aqueous solution) to 3.5% (30% PPG 4000 in aqueous solution). The North American Contact Dermatitis Group (NACDG) data from 1996 to 2006 showed that the most common site for PPG 4000 contact dermatitis was the face (25.9%), followed by a generalized or scattered pattern (23.7%).[61] Investigators believe that the incidence of allergic contact dermatitis to PPG 4000 may be greater than 2% in patients with eczema or fungal infections, which are very common in countries with lesser sun exposure and lower-than-normal vitamin D balances. Therefore, PPG 4000 allergy is more common in those countries. Because of its potential for allergic reactions and frequent use across a variety of topical and systemic products, PPG 4000 was named the American Contact Dermatitis Society's Allergen of the Year for 2018.[65][66] Recent publication from The Mayo Clinic reported 0.85% incidence of positive patch tests to PPG 4000 (100/11,738 patients) with an overall irritant rate of 0.35% (41/11,738 patients) during a 20-year period of 1997–2016.[67] 87% of the reactions were classified as weak and 9% as strong. The positive reaction rates were 0%, 0.26%, and 1.86% for 5%, 10%, and 20% PPG 4000 respectively, increasing with each concentration increase. The irritant reaction rates were 0.95%, 0.24%, and 0.5% for 5%, 10%, and 20% PPG 4000, respectively. PPG 4000 skin sensitization occurred in patients sensitive to a number of other concomitant positive allergens, most common of which were: Myroxylon pereirae resin, benzalkonium chloride, carba mix, potassium dichromate, neomycin sulfate; for positive PPG 4000 reactions, the overall median of 5 and mean of 5.6 concomitant positive allergens was reported. For PPG 4000 (USEPA/OPP Pesticide Code: 068602) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses. Of all polyether polyols (incl PPG 4000, polyethylene glycol, and propylene oxide-ethylene oxide copolymers), 65% were used in polyurethane flexible foam; 9% in polyurethane rigid foam; 7% in noncellular polyurethane applications; 8% for surface-active agents; 8% for lubricants and functional fluids; & 3% for misc applications. There are 2 active ingredients in reregistration case 3123 for PPG 4000. The RED evaluates the only active ingredient in this case with currently registered products; therefore, only butoxyPPG 4000 (BPG), PC Code 011901/CAS No. 9003-13-8, 57 active products as of September, 2001/ was assessed. The other active ingredient in this case /poly(oxy(methyl-1,2ethanediyl)), alpha-hydro-omegahydroxy,CAS No. 25322-69-4 / has no product registrations /last pesticide product cancelled October 10, 1989/ and is not being supported for reregistration. This active ingredient would be evaluated only if and when new registration applications were to be submitted for new products. Method for determination of PPG 4000 at sub-ppm levels in aqueous and organic media by gas-liquid chromatography or by gas chromatography-mass spectroscopy. PPG 4000 is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. This action promulgates standards of performance for equipment leaks of Volatile Organic Compounds (VOC) in the Synthetic Organic Chemical Manufacturing Industry (SOCMI). The intended effect of these standards is to require all newly constructed, modified, and reconstructed SOCMI process units to use the best demonstrated system of continuous emission reduction for equipment leaks of VOC, considering costs, non air quality health and environmental impact and energy requirements. PPG 4000 is produced, as an intermediate or a final product, by process units covered under this subpart. PPG 4000 (minimum molecular weight 150) is an indirect food additive for use only as a component of adhesives. Acute Exposure/ Propylene glycol was relatively harmless (LD50 = 21 g/kg) in acute oral toxicity studies involving rats. Acute oral toxicity studies on PPG 4000s of various molecular weights (300 to 3900 Da) have indicated LD50 values (rats) ranging from 0.5 to >40g/kg. LABORATORY ANIMALS: Acute Exposure/ Single and repeated applications of Polypropylene glycol 425, Polypropylene glycol 1025, and Polypropylene glycol 2025 did not cause skin irritation in the rabbit. Repeated applications of Polypropylene glycol 1200 to rabbits caused mild reactions at abraded skin sites and no reactions at intact sites. Results were negative for 100% PG in a mouse external ear swelling sensitization test. The results of a guinea pig maximization, open epicutaneous, and Finn chamber tests indicated no sensitization reactions to 70%PG. In another maximization test, PG was classified as a potentially weak sensitizer. The results of six other guinea pig sensitization tests indicated that PG was not an allergen. NIOSH (NOES Survey 1981-1983) has statistically estimated that 217,886 workers (30,699 of these were female) were potentially exposed to PPG 4000 in the US(1). Occupational exposure to PPG 4000 may occur through inhalation where mists are formed from violent agitation or high temperatures, and dermal contact with this compound at workplaces where PPG 4000 is produced or used(2). General description of PPG 4000 PPG 4000 is an aliphatic alcohol. It is an addition polymer of PPG 4000 and water represented as H[OCH3]nOH in which n represents the average number of oxypropylene groups. Application of PPG 4000 PPG 4000 (PPG) may be used as a viscosity decreasing agent, a solvent and a fragrance ingredient in cosmetics. PPG 4000 may be used as a good swelling agent for the synthesis of large pore mesoporous materials. What Is It? PPG 4000, also known as 1,2-propanediol, is a synthetic (i.e., man-made) alcohol that attracts/absorbs water. It is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. PPG 4000 is one of the most widely used ingredients in cosmetics and personal care products, including facial cleansers, moisturizers, bath soaps, shampoos and conditioners, deodorants, shaving preparations, and fragrances. In addition to its use as an ingredient in cosmetic and personal care products, it is used in numerous food items such as beer, packaged baked goods, frozen dairy products, margarine, coffee, nuts, and soda. It is also used as an inactive ingredient (e.g., solvent) in many drugs. FDA has approved its use at concentrations as high as 98% in drugs applied to the skin and 92% in drugs taken orally. Why is it used in cosmetics and personal care products? Because PPG 4000 attracts water it functions as a humectant and is used in moisturizers to enhance the appearance of skin by reducing flaking and restoring suppleness. Other reported uses include skin-conditioning agent, viscosity-decreasing agent, solvent, and fragrance ingredient. PPG 4000 was reported to be used in 14,395 products, according to 2019 data in U.S. FDA’s Voluntary Cosmetic Registration Program (VCRP). PPG 4000 is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. PPG 4000 may initiate the polymerization of isocyanates and epoxides. In dilute aqueous solution unimers of Pluronic F127 associate to form micelles. In more concentrated solution, micelles pack to form high-modulus gels. Our interest is the effect of addition of 10–30 wt % low molecular weight PPG 4000 on the micellization and gelation of solutions of F127. DLS was used to determine the apparent size of the micelles (rh,app). The critical micelle concentration (cmc) using the dye solubilization method of F127 in PPG 4000 solutions was studied. Visual observation was carried out to detect gel formation in concentrated solutions and the onset of clouding and turbidity, as the temperature was raised. Oscillatory rheometry was used to confirm the formation of high-modulus gels and provide values of elastic moduli (G′max) over a wide temperature range. SAXS was used to determine gel structure. Our results for the hydrophobic adduct PPG 4000 were compared with literature values for the hydrophilic adduct PEG6000.
PPG 4000 ( (POLI PROPILEN GLIKOL 4000)
Polypropylene glycol 600; Methylethyl glycol; Methylethylene glycol; 1,2-Propanediol; alpha-Propylene glycol; Methyl glycol; Monopropylene glycol; PG; 1,2-Dihydroxypropane; 1,2-Propylene Glycol; 2-Hydroxypropanol; 2,3-Propanediol; Propane-1,2-diol; Trimethyl glycol; 1,2-Propylenglykol; Isopropylene glycol; cas no: 25322-69-4
PPG 600 (POLI PROPILEN GLIKOL 600)
Polypropylene glycol 900; Methylethyl glycol; Methylethylene glycol; 1,2-Propanediol; alpha-Propylene glycol; Methyl glycol; Monopropylene glycol; PG; 1,2-Dihydroxypropane; 1,2-Propylene Glycol; 2-Hydroxypropanol; 2,3-Propanediol; Propane-1,2-diol; Trimethyl glycol; 1,2-Propylenglykol; Isopropylene glycol; cas no: 25322-69-4
PPG 900  (POLI PROPILEN GLIKOL900)
Polyoxypropylene 15 stearyl ether [USAN]; Polypropylene glycol (11) stearyl ether; Polypropylene glycol (15) stearyl ether. cas no: 25231-21-4
PPG-15 STEARYL ETHER
POLYPROPYLENE GLYCOL ETHER OF CAPRYLIC ALCOHOL; POLY(OXY-1-METHYL-1,2-ETHANDIYL), ALPHA-OCTYL-OMEGA-HYDROXY- (3 MOL PO AVERAGE MOLAR RATIO) CAS NO:29117 – 02 – 0
PPG-20 METHYL GLUCOSE ETHER
PPG-20 Methyl Glucose Ether is a polypropylene glycol ether of methyl glucose.
PPG-20 methyl glucose ether is derived from glucose and plant-based oils, it is a clear, and colorless liquid that is largely soluble in water.
PPG-20 methyl glucose ether is known for its ability to improve the texture of skincare and haircare products, making them smoother and more spreadable.


CAS Number: 61849-72-7
Chem/IUPAC Name: Poly[oxy(methyl-1,2-ethanediyl)], .alpha.-hydro-.omega.-hydroxy-, ether with methyl .beta.-d-glucopyranoside (4:1)
Molecular Formula: C31H70O18
MDL Number: MFCD08064623


PPG-20 methyl glucose ether also helps to moisturize the surface that it is applied on and lock in hydration, leaving the surface feeling soft and supple.
PPG-20 methyl glucose ether is a humectant and emollient added to many personal care products.
The chemical formula for PPG-20 methyl glucose ether is C31H70O18.


PPG-20 Methyl Glucose Ether is made by combining plant-based oils and glucose.
The process involves the reaction of the oils with glucose to form a complex mixture of esters.
This mixture is then further processed to produce the final ingredient.
PPG-20 methyl glucose ether is a blend of polypropylene glycol and methyl glucose derivatives that helps soften and smooth skin and hair.


PPG-20 methyl glucose ether is considered an excellent hydrating ingredient due to its humectant (water-binding) properties.
According to suppliers of PPG-20 methyl glucose ether, it comes as a pale yellow, medium-viscosity liquid in its raw material form and is obtained from corn.
In 2016, the Cosmetic Ingredient Review Expert Panel concluded PPG-20 methyl glucose ether is a safe cosmetic ingredient. 


PPG-20 methyl glucose ether is a synthetic polymer made up of methyl glucose ether and polypropylene glycol.
The number represents the number of PPG-20 methyl glucose ether units in the polymer chain.
PPG-20 methyl glucose ether is light in color and soluble in oils and other organic solvents.
PPG-20 methyl glucose ether is a corn-based methyl glucoside derivative that delivers moisture to the skin without leaving a tacky residue.


In alcohol based systems PPG-20 methyl glucose ether reduces the stinging effect alcohol has on skin.
Equally important in fragrance containing formulations, PPG-20 methyl glucose ether acts as a fixative by subduing volatilization of the "high notes".
The light color and low odor of PPG-20 methyl glucose ether will not interfere with the mood the fragrance is trying to communicate.


PPG-20 methyl glucose ether is a light yellow liquid with mild characteristic odor.
PPG-20 methyl glucose ether is a blend of polypropylene glycol and methyl glucose derivatives that helps soften and smooth skin and hair.
PPG-20 methyl glucose ether is considered an excellent hydrating ingredient due to its humectant (water-binding) properties.
According to suppliers of PPG-20 methyl glucose ether , it comes as a pale yellow, medium-viscosity liquid in its raw material form and is obtained from corn.


PPG-20 methyl glucose ether is an emollient.
PPG-20 methyl glucose ether is one of the few naturally-derived cosmetic fluids that are miscible with water, alcohols, organic esters, and oils.
PPG-20 methyl glucose ether delivers humectancy with a lubricious, emollient feel.


In alcohol-based systems PPG-20 methyl glucose ether reduces the stinging effect alcohol has on skin.
PPG-20 methyl glucose ether is miscible with water, alcohols, organic esters and oils.
PPG-20 methyl glucose ether has a lubricious, emollient feel.
PPG-20 methyl glucose ether reduces the stinging of alcohol.


PPG-20 methyl glucose ether is glossing aid.
PPG-20 methyl glucose ether can be safely handled without any irritation caused to the skin, and should be stored in a closed system and be kept in a dark place without any light exposure.
"PPG" refers to a PPG-(polypropylene glycol-) derivative.


The number behind "PPG-" (in the event of mixed PEG/PPG derivatives, the second number) states the average number of molecular units -CH2-CH2-CH2-O-.
"Methyl" mostly refers to methanol (methyl alcohol) as alcoholic component or generally the methyl group as the smallest hydrocarbon residue with one carbon atom.


Dimethyl-, trimethyl- etc refer to two, three or more methyl groups.
PPG-20 methyl glucose ether is an ingredient on the basis of glucose (dextrose).
"Ether" refers to a connection product (condensation product) of two alcohols.
PPG-20 methyl glucose ether is mixing soluble with polar solvents, as water and ethyl alcohol and also with nonpolar solvents, for example, isopropyl palmitate.


PPG-20 methyl glucose ether is a polypropylene glycol ether of methyl glucose.
PPG-20 methyl glucose ether is one of the few naturally derived cosmetic fluids that are miscible with water, alcohols, organic esters, and oils.
In any product, PPG-20 methyl glucose ether delivers humectancy with a lubricious, emollient feel.


In alcohol based systems PPG-20 methyl glucose ether reduces the stinging effect alcohol has on skin.
Equally important in fragrance containing formulations, PPG-20 methyl glucose ether acts as a fixative by subduing volatilization of the "high notes".
The light color and low odor of PPG-20 methyl glucose ether will not interfere with the mood the fragrance is trying to communicate.


PPG-20 methyl glucose ether is a naturally-derived, 100% active, propoxylated methyl glucose ether.
PPG-20 methyl glucose ether offers lubricious, luxurious emollient feel, reduces stinging effect and depresses freezing point.
PPG-20 methyl glucose ether provides fragrance fixation by subduing volatilization of high notes.


PPG-20 methyl glucose ether is derived from corn based Methyl glucoside that is so mild for skin and is completely miscible in water, alcohol and is partially or completely miscible in extract oils and fragrance oils.
PPG-20 methyl glucose ether is a viscous liquid, pale yellow, odorless, soluble in water , alcohol and most oils and organic solvents (except hydrocarbons).


PPG-20 methyl glucose ether is a glucose-derived raw material that greatly increases the long-lasting strength of many fragrances without creating its own odor.
This is PPG-20 methyl glucose ether used for the fixing of top and some middle notes.
For example, experiments performed in house show that Sweet Orange essential oil (one of the most fleeting of scents- usually lasting only two minutes on the skin) was increased to last half an hour or more on the skin.


PPG-20 methyl glucose ether is a naturally-derived, 100% active, propoxylated methyl glucose ether.
PPG-20 methyl glucose ether methyl glucose ether is a material extracted from glucose that has the ability to store and disperse a strong scent without affecting the original scent.



USES and APPLICATIONS of PPG-20 METHYL GLUCOSE ETHER:
PPG-20 methyl glucose ether also can be used effectively as humectant and emollient in the cosmetics field and helps fragrance keep lasting longer.
PPG-20 methyl glucose ether is used Perfume, Skin and Hair care, Shampoo and bath soap, Antiperspirant and deodorant.
Application of PPG-20 methyl glucose ether: perfume, soap, cleaning products.


PPG-20 methyl glucose ether is sometimes used to enhance the texture of cosmetic formulas.
PPG-20 methyl glucose ether is sometimes used to enhance the texture of cosmetic formulas.
Equally important in fragrance containing formulations, PPG-20 methyl glucose ether acts as a fixative by subduing volatilization of the "high notes"


PPG-20 methyl glucose ether is an extremely effective fragrance fixative and humectant for hair care and skin care products.
PPG-20 methyl glucose ether is used as freezing point depressant.
PPG-20 methyl glucose ether can be widely used in detergents, creams, perfumes and other products, and has the functions of reducing viscosity, increasing foam, lowering melting point, moisturizing, solubilizing and fixing fragrance


PPG-20 methyl glucose ether is used as wetting agent, skin caring agent, emulsifying agent and fixative.
According to the above properties, PPG-20 methyl glucose ether can be widely used in detergents, creams, perfumes and other products, and has the functions of reducing viscosity, increasing foam, lowering melting point, moisturizing, solubilizing and fixing fragrance.


PPG-20 methyl glucose ether humectant is used in hand soaps, shampoos, shaving & styling preparations and facial care products.
According to CosIng 's classification , PPG-20 methyl glucose ether is used a skin and hair conditioning ingredient, and according to a company that manufactures and distributes the ingredient, it is primarily a water-binding, moisturizing and skin-softening (emollient) substance, and secondarily a fragrance enhancer.


PPG-20 methyl glucose ether is a mild, non-irritative moisturizer derived from natural glucose.
PPG-20 methyl glucose ether can be mixed with water, alcohol and grease, providing favorable moisturization, lubricity and emollience.
PPG-20 methyl glucose ether’s widely used in skin care, hair care and body wash products, reducing irritation to skin caused by alcohol.
PPG-20 methyl glucose ether also helps to fix fragrance.


PPG-20 methyl glucose ether is used up to 5% of your fragrance formula concentrate, but experiment!
Using too much will "flatten" a fragrance.
According to the above properties, PPG-20 methyl glucose ether can be widely used in detergents, creams, perfumes and other products, and has the functions of reducing viscosity, increasing foam, lowering melting point, moisturizing, solubilizing and fixing fragrance.


PPG-20 methyl glucose ether is one of the few naturally-derived cosmetic fluids that are miscible with water, alcohols, organic esters, and oils.
In any product, PPG-20 methyl glucose ether delivers humectancy with a lubricious, emollient feel.
In alcohol-based systems PPG-20 methyl glucose ether reduces the stinging effect alcohol has on skin.


Equally important in fragrance-containing formulations, PPG-20 methyl glucose ether acts as a fixative by subduing volatilization of the "high notes".
The light color and low odor of PPG-20 methyl glucose ether will not interfere with the mood the fragrance is trying to communicate.


PPG-20 methyl glucose ether is recommended for use in hair care and skin care products.
PPG-20 methyl glucose ether's raw materials can be widely used in detergents, creams, perfumes and other products to reduce viscosity, increase foam, reduce melting point, moisturize, increase dissolution, and fix fragrance.


-Cosmetic Uses of PPG-20 methyl glucose ether:
*hair conditioning
*skin conditioning


-Uses of PPG-20 methyl glucose ether:
*Helps preserve perfume scent
*As a humectant
*Increased stability
*Reduces anti-sweat white discoloration
*Increase the sense of smell and spread good scent
*Fixed fragrance


-Applications of PPG-20 methyl glucose ether:
• Used with MeG SSE-20, can provide long-term shelf life and viscosity stability
• Auxiliary emulsifier for all systems
• Generates and stabilizes viscosity
• Strengthens and rigidifies molded sticks; reduces synergetic
• Supplemental stabilizer for multiple phase makeup products
• Mild barrier supplement for moisture retention in topical products
• Improves lather texture



USES AND BENEFITS OF PPG-20 METHYL GLUCOSE ETHER:
PPG-20 Glucose Methyl Ether functions as a hair and skin conditioning agent.
As a skin conditioning agent, PPG-20 methyl glucose ether forms a protective film on the skin surface that prevents moisture loss from the skin and lubricates it.
When used on the hair, PPG-20 methyl glucose ether forms a protective layer on the hair and prevents it from drying out.

PPG-20 methyl glucose ether gives it a smooth and silky look.
Depending on its chemical structure, PPG-20 methyl glucose ether also functions as an emollient and surfactant in cosmetic products.
A surfactant is one that works more or less like a detergent.
Chemically, ether (-O-), which is the binding link between PPG-20 methyl glucose ether and methylglucose, imparts a loving characteristic to fat, while PPG and methylglucose, separately, are loving of water by nature.

Therefore, When combined, they are effective against dirt and dead bacteria, since they are grease-loving.
They stick to dirt and bacteria on the skin and wash away with water.
Both PPG-20 methyl glucose ether and methyl glucose have some functional groups that attract water and hold it for use by skin cells.
Therefore, they can also work as emollients.

PPG-20 methyl glucose ether is used in formulations of creams, lotions, moisturizers, conditioners, and other skin and hair care products.
Both PPG-20 methyl glucose ether and methylglucose have some functional groups that attract water and hold it for use by skin cells.
Therefore, they can also work as emollients.

PPG-20 methyl glucose ether is used in formulations of creams, lotions, moisturizers, conditioners, and other skin and hair care products.
Both PPG-20 methyl glucose ether and methylglucose have some functional groups that attract water and hold it for use by skin cells.
Therefore, they can also work as emollients.
PPG-20 methyl glucose ether is used in formulations of creams, lotions, moisturizers, conditioners, and other skin and hair care products.



WHAT IS PPG-20 METHYL GLUCOSE ETHER USED FOR?
PPG-20 methyl glucose ether is a very useful ingredient that is commonly used in personal care products.
PPG-20 methyl glucose ether has moisturizing and emollient properties that are beneficial for hair and skin formulations.
In hair care products, PPG-20 Methyl Glucose Ether acts as a humectant, helping to retain moisture and prevent dryness.
This helps keep hair feeling soft, smooth, and hydrated.
PPG-20 methyl glucose ether also aids in moisturizing and soothing the skin, leaving it feeling nourished.
PPG-20 methyl glucose ether has a smoothing effect on the skin, which makes it a popular ingredient in anti-aging formulations.
PPG-20 methyl glucose ether can be found in shampoos, conditioners, lotions, and creams, and is often used in combination with other ingredients to enhance its benefits.



CHEMICAL PROPERTY OF PPG-20 METHYL GLUCOSE ETHER:
PPG-20 methyl glucose ether is a new product developed by our company.
PPG-20 methyl glucose ether has the feature of reducing the viscosity of surfactants and foaming.
PPG-20 methyl glucose ether is used as a wetting agent, skin care agent, emulsifying agent and fixative.
PPG-20 methyl glucose ether is mixed with polar solvents such as water and ethyl alcohol, as well as with non-polar solvents such as isopropyl palmitate.



PPG-20 METHYL GLUCOSE ETHER AT A GLANCE:
*Blend of polypropylene glycol + methyl glucose derivatives
*Helps soften and smooth skin and hair
*Excellent hydrating ingredient due to its humectant (water-binding) properties
*Can be used to enhance the texture of cosmetic formulas



FUNCTIONS OF PPG-20 METHYL GLUCOSE ETHER:
*Hair conditioner: Leaves hair easy to comb, supple, soft and shiny and/or gives volume, lightness and shine
*Skin conditioning agent: Keeps the skin in good condition
*PPG-20 methyl glucose ether is an extremely effective emollient, fragrance fixative and humectant for hair care and skin care products.



KEY FEATURES AND BENEFITS OF PPG-20 METHYL GLUCOSE ETHER:
• Derived from natural sources
• Humectancy
• Stability enhancement
• Reduction of antiperspirant white stain transfer marks
• Good spreading and sensory profile
• Mildness
• Fragrance fixation



PPG-20 METHYL GLUCOSE ETHER BELONGS TO THE FOLLOWING SUBSTANCE GROUPS:
*Haircare substances / Conditioning agents
*Ingredients for skincare



FUNCTIONS OF PPG-20 METHYL GLUCOSE ETHER IN COSMETIC PRODUCTS:
*HAIR CONDITIONING:
Leaves the hair easy to comb, supple, soft and shiny and / or imparts volume
*SKIN CONDITIONING:
Maintains the skin in good condition



BACKGROUND INFORMATION ON USE IN COSMETICS:
Polypropylene glycol (PPGs) and their derivatives are used in cosmetic products like the polyethylene glycols (PEGs).
They are often used in cosmetic products since they have a broad range of viscosity and solubility properties and have a very good skin tolerance.
As water soluble, non-greasy substances, polypropylene glycols are suited for many cosmetic purposes.
The liquid PPGs serve, for instance, as solubilizers and solvents.



HOW DOES PPG-20 METHYL GLUCOSE ETHER WORK:
PPG-20 methyl glucose ether is an antistatic substance.
PPG-20 methyl glucose ether keeps moisture on the surface of the skin and prevents evaporation of moisture from the surface.
PPG-20 methyl glucose ether nourishes and moisturizes the skin.



FROM THE SCIENTIFIC SIDE OF PPG-20 METHYL GLUCOSE ETHER:
PPG-20 methyl glucose ether is a synthetic ingredient, polypropylene glycol.
PPG-20 methyl glucose ether acts as a hair and skin supplement.



WHAT DOES PPG-20 METHYL GLUCOSE ETHER DO IN A FORMULATION?
*Emollient
*Hair conditioning
*Humectant
*Skin conditioning



PHYSICAL and CHEMICAL PROPERTIES of PPG-20 METHYL GLUCOSE ETHER:
Molecular Weight: 730.9
Hydrogen Bond Donor Count: 12
Hydrogen Bond Acceptor Count: 18
Rotatable Bond Count: 18
Exact Mass: 730.45621538
Monoisotopic Mass: 730.45621538
Topological Polar Surface Area: 298 Ų
Heavy Atom Count: 49
Formal Charge: 0
Complexity: 228
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 5
Undefined Atom Stereocenter Count: 8
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0

Covalently-Bonded Unit Count: 5
Compound Is Canonicalized: Yes
Appearance: Pale yellow viscous syrup
Assay: Min. 99.0%
Odor: Mild
Acid number, mg/g: Max. 11
Hydroxyl value, mg/g: 270-305
Moisture, % WT.: Max. 1.0
Saponification value, mg/g: 125-140
Iodine value: 1
Ash, % WT.: Max. 0.5
Color, Gardner: Max. 7
Melt range, °C: 48-55
Appearance: Pale yellow viscous syrup
Assay: Min. 99.0%

Odor: Mild
Acid number, mg/g: Max. 11
Hydroxyl value, mg/g: 270-305
Moisture, % WT.: Max. 1.0
Saponification value, mg/g: 125-140
Iodine value: 1
Ash, % WT.: Max. 0.5
Color, Gardner: Max. 7
Melt range, ℃: 48-55
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 389.10 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.000000 mmHg @ 25.00 °C. (est)
Flash Point: 372.00 °F. TCC ( 189.10 °C. ) (est)
logP (o/w): -2.690 (est)
CAS No.: 61849-72-7
Molecular Formula: C31H70O18
Formula Weight: 730.8767
Assay: 98%

Physical state: no data available
Colour: no data available
Odour: no data available
Melting point/ freezing point: no data available
Boiling point or initial boiling point and boiling range: 389.1\u00baC at 760 mmHg
Flammability: no data available
Lower and upper explosion limit / flammability limit: no data available
Flash point: 189.1\u00baC
Auto-ignition temperature: no data available
Decomposition temperature: no data available
pH: no data available
Kinematic viscosity: no data available
Solubility: no data available
Partition coefficient n-octanol/water (log value): no data available
Vapour pressure: no data available
Density and/or relative density: no data available
Relative vapour density: no data available
Particle characteristics: no data available

Molecular Formula: C31H70O18
Molar Mass: 730.8767
Boling Point: 389.1°C at 760 mmHg
Flash Point: 189.1°C
Vapor Presure: 1.15E-07mmHg at 25°C
Appearance: colorless to light yellow clear liquid
Acidity: ≤1
Saponification value: ≤1
Hydroxyl value: 160-180
Iodine value: ≤1
Moisture: ≤1
Assay: 95.00 to 100.00 %
Food Chemicals Codex Listed: No
Boiling Point: 389.10 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.000000 mmHg @ 25.00 °C. (est)
Flash Point: 372.00 °F. TCC ( 189.10 °C. ) (est)
logP (o/w): -2.690 (est)



FIRST AID MEASURES of PPG-20 METHYL GLUCOSE ETHER:
-Description of necessary first-aid measures:
*General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
*If swallowed:
Rinse mouth with water.
Consult a physician.
-Most important symptoms/effects, acute and delayed:
no data available
-Indication of immediate medical attention and special treatment needed, if necessary:
no data available



ACCIDENTAL RELEASE MEASURES of PPG-20 METHYL GLUCOSE ETHER:
-Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.
-Methods and materials for containment and cleaning up:
Pick up and arrange disposal.
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of PPG-20 METHYL GLUCOSE ETHER:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Specific hazards arising from the chemical:
no data available
-Special protective actions for fire-fighters:
Wear self-contained breathing apparatus for firefighting if necessary.



EXPOSURE CONTROLS/PERSONAL PROTECTION of PPG-20 METHYL GLUCOSE ETHER:
-Control parameters:
*Occupational Exposure limit values:
no data available
*Biological limit values:
no data available
-Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
-Individual protection measures, such as personal protective equipment (PPE):
*Eye/face protection:
Safety glasses with side-shields.
Use equipment for eye protection.
*Skin protection:
Wear impervious clothing.
Handle with gloves.
Wash and dry hands.
-Thermal hazards:
no data available



HANDLING and STORAGE of PPG-20 METHYL GLUCOSE ETHER:
-Conditions for safe storage, including any incompatibilities:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of PPG-20 METHYL GLUCOSE ETHER:
-Reactivity:
no data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
no data available
-Conditions to avoid:
no data available
-Incompatible materials:
no data available
-Hazardous decomposition products:
no data available



SYNONYMS:
PPG-20 METHYL GLUCOSE ETHER
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-methoxyoxane-3,4,5-triol
2-(2-hydroxypropoxy)propan-1-ol
GLUCAM P-10/20
PPG-20 METHYL GLUCOSE ETHER
Methyl glucoside propoxylate
ylbeta-d-glucopyranoside(4:1)
PPG-20 Methyl glucoside propoxylate
B-Methyl D-glucopyranoside, propoxylated
Polypropylene glycol beta-methyl glucoside ether (4:1)
PPG-20 methyl glucose ether ( P-20 from Amerchol of Dow)
Polypropylene glycol methyl beta-glucopyranoside ether (4:1)
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-methoxyoxane-3,4,5-triol
PPG-10 METHYL GLUCOSE ETHER
Methyl glucoside propoxylate
B-Methyl D-glucopyranoside, propoxylated
2-(2-hydroxypropoxy)propan-1-ol-methyl beta-D-glucopyranoside (4:1)
Glucam P-10/20
MeG P-20
PPG-20 Methyl Glucose Ether
Methyl Glucose Ether
glucam p-10/20
polypropylene glycol methyl beta-glucopyranoside ether (4:1)
poly[oxy(methyl-1,2-ethanediyl)], α-hydro-ω-hydroxy-
ether with methyl -d-glucopyranoside (4:1)
ylbeta-d-glucopyranoside(4:1)
poly[oxy(methyl-1,2-ethanediyl)],α-hydro-w-hydroxy-
ether with methyl bd-glucopyranoside (4:1)
ppg-20 methyl glucose ether
methylglucoside propoxylate
methyl glucoside propoxylate
polypropylene glycol beta-methyl glucoside ether (4:1)
b-methyl d-glucopyranoside, propoxylated
ppg-20 methyl glucose ether ( p-20 from amerchol of dow)
GlucamP20
Unicam P20
Propoxylated Alcohol
PPG-20 Methyl Glucose Ether
Methyl glucoside propoxylate
B-Methyl D-glucopyranoside, propoxylated
POLYOXYPROPYLENE (20) METHYL GLUCOSE ETHER
POLYPROPYLENE GLYCOL (20) METHYL GLUCOSE ETHER
PPG-20 METHYL GLUCOSE ETHER


PPG-20 METHYL GLUCOSE ETHER
PPG-20 methyl glucose ether is a blend of polypropylene glycol and methyl glucose derivatives that helps soften and smooth skin and hair.
PPG-20 methyl glucose ether is considered an excellent hydrating ingredient due to its humectant (water-binding) properties.
PPG-20 methyl glucose ether is sometimes used to enhance the texture of cosmetic formulas.

CAS Number: 61849-72-7
Molecular Formula: C31H70O18
Molecular Weight: 730.8767

PPG-20 METHYL GLUCOSE ETHER, (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-methoxyoxane-3,4,5-triol;2-(2-hydroxypropoxy)propan-1-ol.

PPG-20 methyl glucose ether is currently not a stock item, it may not be available at the moment.
However, our global sourcing specialists can support in line with your product specification and your preferences.
PPG-20 methyl glucose ether also helps to moisturize the surface that it is applied on and lock in hydration, leaving the surface feeling soft and supple.

PPG-20 methyl glucose ether is known for its ability to improve the texture of skincare and haircare products, making them smoother and more spreadable.
PPG-20 methyl glucose ether is a humectant and emollient added to many personal care products
According to suppliers of PPG-20 methyl glucose ether, it comes as a pale yellow, medium-viscosity liquid in its raw material form and is obtained from corn.

PPG-20 Methyl Glucose Ether is a humectant and emollient added to many personal care products.
Derived from glucose and plant-based oils, it is a clear, and colorless liquid that is largely soluble in water.
PPG-20 Methyl Glucose Ether is known for its ability to improve the texture of skincare and haircare products, making them smoother and more spreadable.

PPG-20 methyl glucose ether also helps to moisturize the surface that it is applied on and lock in hydration, leaving the surface feeling soft and supple.
The chemical formula for PPG-20 Methyl Glucose Ether is C31H70O18.
PPG-20 methyl glucose ether is a very useful ingredient that is commonly used in personal care products.

PPG-20 methyl glucose ether has moisturizing and emollient properties that are beneficial for hair and skin formulations.
In hair care products, PPG-20 Methyl Glucose Ether acts as a humectant, helping to retain moisture and prevent dryness.
This helps keep hair feeling soft, smooth, and hydrated.

PPG-20 Methyl Glucose Ether also aids in moisturizing and soothing the skin, leaving it feeling nourished.
PPG-20 methyl glucose ether has a smoothing effect on the skin, which makes it a popular ingredient in anti-aging formulations.
PPG-20 Methyl Glucose Ether can be found in shampoos, conditioners, lotions, and creams, and is often used in combination with other ingredients to enhance its benefits.

PPG-20 Methyl Glucose Ether is a cosmetic ingredient commonly used in skincare and hair care products.
PPG-20 Methyl Glucose Ether is made by combining plant-based oils and glucose.
The process involves the reaction of the oils with glucose to form a complex mixture of esters.

This mixture is then further processed to produce the final ingredient.
PPG-20 methyl glucose ether humectant is a naturally-derived, 100% active, propoxylated methyl glucose ether.
PPG-20 methyl glucose ether is one of the few naturally-derived cosmetic fluids that are miscible with water, alcohols, organic esters, and oils.

In any product, it delivers humectancy with a lubricious, emollient feel.
In alcohol-based systems Glucam P-20 humectant reduces the stinging effect alcohol has on skin.
Equally important in fragrance containing formulations, it acts as a fixative by subduing volatilization of the "high notes".

The light color and low odor of Glucam P-20 humectant will not interfere with the mood the fragrance is trying to communicate.
PPG-20 methyl glucose ether is recommended for use in hair care and skin care products.
Derived from glucose and plant-based oils, PPG-20 methyl glucose ether is a clear, and colorless liquid that is largely soluble in water.

The chemical formula for PPG-20 methyl glucose ether is C31H70O18.
PPG-20 methyl glucose ether is a very useful ingredient that is commonly used in personal care products.
PPG-20 methyl glucose ether has moisturizing and emollient properties that are beneficial for hair and skin formulations.

PPG-20 methyl glucose ether Applications :
PPG-20 methyl glucose ether is used as wetting agent, skin caring agent, emulsifying agent and fixative.
PPG-20 methyl glucose ether is mixing soluble with polar solvents, as water and ethyl alcohol and also with nonpolar solvents, for example, isopropyl palmitate.

PPG-20 methyl glucose ether is a Diester of PPG20 methyl glucose ether and stearic acid PPG-20 methyl glucose ether distearate uses and applications include: Humectant, moisturizer, conditioner, and emollient for cosmetics and pharmaceuticals; binder and plasticizer for pressed powders.
PPG-20 methyl glucose ether is one of the few naturally derived cosmetic fluids that are miscible with water, alcohols, organic esters, and oils.
In any product, PPG-20 methyl glucose ether delivers humectancy with a lubricious, emollient feel.

PPG-20 methyl glucose ether is a mild, non-irritative moisturizer derived from natural glucose.
PPG-20 methyl glucose ether can be mixed with water, alcohol and grease, providing favorable moisturization, lubricity and emollience.
PPG-20 methyl glucose ether’s widely used in skin care, hair care and body wash products, reducing irritation to skin caused by alcohol.

PPG-20 methyl glucose ether also helps to fix fragrance. We also supply other cosmetic materials.
PPG-20 Methyl Glucose Ether acts as a surfactant, helping to reduce the surface tension of liquids.
This property allows the product to spread more easily on the skin or hair.

PPG-20 methyl glucose ether can function as an emollient, contributing to the softening and smoothing of the skin or hair.
PPG-20 methyl glucose ether may have humectant properties, helping to retain moisture and keep the skin or hair hydrated.
PPG-20 methyl glucose ether is often used to improve the texture and feel of cosmetic products, making them more pleasant to use.

PPG-20 methyl glucose ether is one of the few naturally-derived cosmetic fluids that are miscible with water, alcohols, organic esters, and oils.
PPG-20 methyl glucose ether delivers humectancy with a lubricious, emollient feel.
In alcohol-based systems it reduces the stinging effect alcohol has on skin.

PPG-20 methyl glucose ether distearate emollient is a naturally-derived 100% active, propoxylated methyl glucose ether.
PPG-20 methyl glucose ether is designed for skin care formulations to deliver safe, effective moisturization without a heavy, greasy feel.
Because PPG-20 methyl glucose ether is mild, vegetable-derived and non-comedogenic, it is especially well suited for products used around the eye or in formulations made for sensitive skin.

In hair care products, PPG-20 methyl glucose ether acts as a humectant, helping to retain moisture and prevent dryness.
This helps keep hair feeling soft, smooth, and hydrated.
PPG-20 methyl glucose ether also aids in moisturizing and soothing the skin, leaving it feeling nourished.

PPG-20 methyl glucose ether has a smoothing effect on the skin, which makes it a popular ingredient in anti-aging formulations.
PPG-20 methyl glucose ether can be found in shampoos, conditioners, lotions, and creams, and is often used in combination with other ingredients to enhance its benefits.
PPG-20 methyl glucose ether indicated, in 2009, as being intended to be registered by at least one company in the EEA.

Such notifications are required for hazardous substances, as such or in mixtures, as well as for all substances subject to registration, regardless of their hazard.
PPG 20 methyl glucose ether comes as a pale yellow, medium-viscosity liquid in its raw material form and is obtained from corn.
PPG 20 methyl glucose ether is a polyethylene glycol ether of the mono anddiesters of methyl glucose and stearic acid with an average of 20 moles of ethylene oxide.

PPG 20 methyl glucose ether is a mild, water-loving emulsifier that's safe for sensitive skin or eye-care formulations.
PPG 20 methyl glucose ether helps to create low viscosity oil-in-water emulsions, ideal for milks, serums, and sprayable formulations.
PPG 20 methyl glucose ether's derived from natural sources and gives a light, satiny afterfeel.

PPG 20 methyl glucose ether is naturally derived emollient that provides hydration without a heavy, greasy feel.
PPG 20 methyl glucose ether is a naturally derived 100% active propoxylated methyl glucose ether. Designed for skin care formulations to provide safe, effective hydration without a heavy, greasy feel.
Since PPG 20 methyl glucose ether is mild, plant-based and non-comedogenic, it is very suitable for products used especially around the eyes or formulations prepared for sensitive skin.

PPG 20 methyl glucose ether is the ether of mono and diester of methyl glucose and stearic acid.
PPG 20 methyl glucose ether is a yellowish paste with a characteristic odor.
PPG 20 methyl glucose ether is a combination of both polyethelene glycol – a water-loving molecule and stearic acid – a fat-loving molecule.

PPG 20 methyl glucose ether is a glucose molecule having a methyl group attached by displacing a hydrogen atom.
PPG 20 methyl glucose ether can be considered as a bulky molecule having surfactant like properties.
PPG 20 methyl glucose ether is an ethoxylated methyl glucose ether which has been esterified with stearic acid.

PPG 20 methyl glucose ether is 100% active and is supplied as a soft solid.
PPG 20 methyl glucose ether has water-in-oil emulsifying activity, and Glucamate SSE-20 emulsifier is an oil-in-water emulsifier
PPG 20 methyl glucose ether is used together, they form a complementary pair offering safety and performance advantages over more conventional emulsifiers.

With extremely low eye irritation scores, these ingredients are perfect for creams, lotions and makeup used near the eye.
PPG 20 methyl glucose ether is used in beauty products and cosmetics as both an emollient and surfactant.

PPG 20 methyl glucose ether is the polyethylene glycol ether of the mono and diesters of Methyl Glucose and Stearic Acid, and is minimally absorbed by skin because of
PPG 20 methyl glucose ether is seen as an ingredient in a large number of products because of their diverse properties

LogP: -2.690 (est)
EWG's Food Scores: 1

PPG-20 methyl glucose ether is a synthetic polymer formed from methyl glucose ether and polypropylene glycol.
The number represents the number of PPG units in the polymer chain.
PPG-20 methyl glucose ether is light in color and soluble in oils and other organic solvents.

PPG-20 methyl glucose ether is a blend of polypropylene glycol and methyl glucose derivatives that helps soften and smooth skin and hair.
PPG-20 methyl glucose ether is considered an excellent hydrating ingredient due to its humectant (water-binding) properties.
PPG-20 methyl glucose ether is sometimes used to enhance the texture of cosmetic formulas.

According to suppliers of PPG-20 methyl glucose ether, it comes as a pale yellow, medium-viscosity liquid in its raw material form and is obtained from corn.
PPG-20 methyl glucose ether emollient is a naturally-derived 100% active, propoxylated methyl glucose ether.
PPG-20 methyl glucose ether is designed for skin care formulations to deliver safe, effective moisturization without a heavy, greasy feel.

Because PPG-20 methyl glucose ether is mild, vegetable-derived and non-comedogenic, it is especially well suited for products used around the eye or in formulations made for sensitive skin.
In fragrance containing formulations, PPG-20 methyl glucose ether acts as a fixative by subduing volatilization of the "high notes".
The light color and low odor of Glucam P20 humectant will not interfere with the mood the fragrance is trying to communicate.

This is also a naturally-derived humectant, 100% active, propoxylated PPG-20 methyl glucose ether.
PPG-20 methyl glucose ether is one of the few naturally-derived cosmetic fluids that are miscible with water, alcohols, organic esters, and oils.
In any product, it delivers humectancy with a lubricious, emollient feel.

In alcohol-based systems GlucamP20 humectant reduces the stinging effect alcohol has on skin.
PPG-20 methyl glucose ether is recommended for use in perfume, fabcon, linen spray, hair care and skin care products.
PPG-20 methyl glucose ether can also be used as humectants to your skin care products like lotion and cream.

PPG-20 methyl glucose ether is one of the few naturally-derived cosmetic fluids that are miscible with water, alcohols, organic esters, and oils.
PPG-20 methyl glucose ether delivers humectancy with a lubricious, emollient feel.
In alcohol-based systems PPG-20 methyl glucose ether reduces the stinging effect alcohol has on skin.

Equally important in fragrance containing formulations, it acts as a fixative by subduing volatilization of the "high notes"
Applications of PPG-20 methyl glucose ether
PPG-20 methyl glucose ether is a synthetic polymer of propylene oxide.

In cosmetics, PPG is often used to enhance the texture and feel of products, providing a smooth and silky consistency.
PPG-20 methyl glucose ether is derived from glucose and is often used in cosmetic formulations for its ability to condition and moisturize the skin.
PPG-20 methyl glucose ether can also act as a humectant, helping to retain moisture.

PPG-20 methyl glucose ether contributes to the emollient properties of skincare and hair care products.
Emollients are substances that help to soften and smooth the skin, improving its texture and appearance.
As a surfactant, PPG-20 methyl glucose ether helps to reduce the surface tension of liquids, aiding in the even distribution of the product and enhancing its spreadability.

PPG-20 methyl glucose ether is water-soluble, making it suitable for a wide range of formulations, including aqueous solutions like lotions and shampoos.
This ingredient is often chosen for its stability in formulations, contributing to the overall stability and shelf life of cosmetic products.
PPG-20 methyl glucose ether functions as a hair and skin conditioning agent.

As a skin conditioning agent forms a protective film on the surface of the skin which prevents loss of moisture from the skin and lubricates it.
When used in hair it forms a protective layer on the hair and prevents it from drying.
PPG-20 methyl glucose ether makes it appear soft and silky.

Depending upon the chemical structure PPG-20 methyl glucose ether also functions as an emollient and surfactant in cosmetic products.
A surfactant is the one that more or less works like a detergent.
Chemically understanding, ether (-O-) being the connecting bond between PPG and Methyl glucose, imparts fat-loving characteristic, while PPG and methyl glucose, individually are water-loving in nature.

So, when they combine, they are effective against dirt and dead bacteria, since they are fat-loving.
They bond with dirt and bacteria present on the skin and get carried away with water. Both PPG and Methyl glucose have some functional groups that attract water and hold it for use for the skin cells.
So, it can function as emollient as well.

PPG-20 methyl glucose ether is used in formulations of creams, lotions, moisturizers, conditioners, and other skin and hair care products.
As with any cosmetic ingredient, PPG-20 methyl glucose ether is important to use products containing PPG-20 Methyl Glucose Ether as directed and discontinue use if any signs of irritation or allergic reaction occur.
PPG-20 methyl glucose ether functions as a hair and skin conditioning agent.

As a skin conditioning agent, PPG-20 methyl glucose ether forms a protective film on the skin surface that prevents moisture loss from the skin and lubricates it.
When used on the hair, it forms a protective layer on the hair and prevents it from drying out.
PPG-20 methyl glucose ether gives it a smooth and silky look.

Depending on its chemical structure, PPG-20 methyl glucose ether also functions as an emollient and surfactant in cosmetic products.
A surfactant is one that works more or less like a detergent.
Chemically, ether (-O-), which is the binding link between PPG and methylglucose, imparts a loving characteristic to fat, while PPG and methylglucose, separately, are loving. of water by nature.

Therefore, when combined, they are effective against dirt and dead bacteria, since they are grease-loving.
They stick to dirt and bacteria on the skin and wash away with water.
Both PPG and methylglucose have some functional groups that attract water and hold it for use by skin cells.

PPG-20 Methyl Glucose Ether can contribute to the hydration of the skin and hair.
PPG-20 methyl glucose ether is humectant properties help attract and retain moisture, promoting a smoother and more moisturized appearance.
In addition to skincare and hair care products, PPG-20 Methyl Glucose Ether is often used in cleansers and foaming products.

PPG-20 methyl glucose ether is surfactant properties make it useful for creating a lathering effect, helping to cleanse the skin or hair effectively.
PPG-20 methyl glucose ether can contribute to the stability of formulations by preventing the separation of oil and water phases in emulsions.
This enhances the overall stability and shelf life of cosmetic products.

As a non-ionic surfactant, PPG-20 Methyl Glucose Ether is generally considered mild and is less likely to cause irritation compared to some other surfactants.
This makes it suitable for use in products designed for sensitive skin.
The presence of a polyol structure (methyl glucose) in the molecule can add a conditioning effect, contributing to the softness and manageability of hair in hair care formulations.

Therefore, they can also work as emollients.
PPG-20 methyl glucose ether is used in formulations of creams, lotions, moisturizers, conditioners, and other skin and hair care products.
PPG-20 Methyl Glucose Ether can contribute to the viscosity control of cosmetic formulations.

PPG-20 methyl glucose ether helps to adjust the thickness or flow of the product, which is crucial for various formulations such as creams, lotions, and gels.
In some formulations, PPG-20 Methyl Glucose Ether may be used in combination with other ingredients to create synergistic effects.
PPG-20 methyl glucose ether can enhance the overall performance and sensory attributes of the product.

This ingredient is often compatible with a wide range of other cosmetic ingredients, making it versatile in formulating different types of personal care products.
PPG-20 Methyl Glucose Ether is non-ionic, meaning it does not carry an electric charge.
This makes it compatible with a variety of cosmetic formulations, including those that are sensitive to changes in pH.

Cosmetic manufacturers often use PPG-20 Methyl Glucose Ether to improve the sensory experience of their products.
The ingredient can contribute to a luxurious feel, ease of application, and a non-sticky finish, which positively influences consumer perception.
PPG 20 methyl glucose ether is a blend of polypropylene glycol and methyl glucose derivatives that helps soften and smooth skin and hair.

PPG 20 methyl glucose ether is considered an excellent hydrating ingredient due to its humectant (water-binding) properties.
PPG 20 methyl glucose ether is sometimes used to enhance the texture of cosmetic formulas.

Uses:
PPG 20 methyl glucose ether is used for its emulsifying properties in cosmetic products.
As an emulsifier, PPG 20 methyl glucose ether gives stability to the product and prevents the oil and water-based components of the product from getting separated.
Since molecules dissolving in water can take up the PPG 20 methyl glucose ether part and oil dissolving molecules will get attached to the stearate part.

PPG 20 methyl glucose ether reduces a chance of inter-reaction of various ingredients and gives noticeable stability to the product.
PPG 20 methyl glucose ether also functions as a thickener by attracting water molecules and gives a sort of ‘swollen’ appearance to its molecule.
PPG 20 methyl glucose ether enhances its overall performance of the product on the skin or hair surface.

PPG 20 methyl glucose ether is used in formulations of creams, lotions, gels, shampoos, and other skincare products.
PPG-20 Methyl Glucose Ether can be included in moisturizers and lotions to provide emollient properties, helping to soften and hydrate the skin.
PPG-20 methyl glucose ether is surfactant properties make it suitable for use in facial cleansers, body washes, and other cleansing products, contributing to foaming and cleansing effects.

PPG-20 Methyl Glucose Ether may be added to hair conditioners to enhance the texture and manageability of the hair, providing a conditioning effect.
In shampoos, PPG-20 methyl glucose ether can contribute to foaming and cleansing properties.
PPG-20 Methyl Glucose Ether helps stabilize emulsions, preventing the separation of oil and water phases.

This is important in formulations like creams and lotions.
PPG-20 methyl glucose ether can be used to adjust the thickness or viscosity of cosmetic products, influencing their texture and application.
PPG-20 methyl glucose ether acts as a humectant, attracting and retaining moisture, which is beneficial for maintaining skin and hair hydration.

Due to its non-ionic nature and mild characteristics, PPG-20 Methyl Glucose Ether is often included in formulations designed for sensitive skin.
PPG-20 methyl glucose ether contributes to the overall sensory experience of a product, providing a smooth and pleasant texture.
PPG-20 Methyl Glucose Ether can be found in some sunscreen formulations, contributing to the overall texture of the product.

PPG-20 methyl glucose ether is water-soluble nature makes it compatible with both water-based and oil-based sunscreen formulations.
In cosmetic products such as foundations, concealers, and BB creams, PPG-20 Methyl Glucose Ether may be used to enhance the spreadability and blendability of the product.
PPG-20 methyl glucose ether is commonly used in various body care products, including body lotions, creams, and shower gels, where it can provide moisturizing and cleansing benefits.

Due to its mildness and moisturizing properties, PPG-20 Methyl Glucose Ether is sometimes included in formulations for baby care products such as baby lotions and washes.
PPG-20 Methyl Glucose Ether can be found in leave-in conditioners, hair serums, and styling products, contributing to the overall manageability and softness of the hair.
PPG-20 methyl glucose ether may be included in the formulation of cosmetic wipes, contributing to the effectiveness of the wipe in removing makeup and impurities.

PPG-20 Methyl Glucose Ether's solubility and mild characteristics make it suitable for use in fragrance formulations, helping to disperse and stabilize fragrance ingredients.
PPG-20 methyl glucose ether can be present in various grooming products for men, such as shaving creams and aftershaves, contributing to their texture and overall performance.
PPG-20 Methyl Glucose Ether may be included in sunscreen formulations to contribute to the overall texture and spreadability of the product.

PPG-20 methyl glucose ether can enhance the user experience by providing a smoother application.
In facial serums, PPG-20 Methyl Glucose Ether can function as a lightweight emollient, helping to deliver active ingredients while providing a non-greasy feel.
PPG-20 Methyl Glucose Ether can be found in various makeup products such as foundations, BB creams, and tinted moisturizers.

PPG-20 methyl glucose ether is emollient properties contribute to a smooth application and help create a desirable finish.
PPG-20 methyl glucose ether is soothing and moisturizing properties make PPG-20 Methyl Glucose Ether suitable for inclusion in after-shave products, helping to calm and hydrate the skin post-shaving.
In pre-shave products like shaving creams or gels, PPG-20 Methyl Glucose Ether can contribute to the overall texture, making it easier for the product to adhere to the skin for a smoother shaving experience.

PPG-20 Methyl Glucose Ether may be used in body creams and body butters to enhance the moisturizing properties, providing a luxurious and soft feel to the skin.
Its water-soluble nature makes PPG-20 Methyl Glucose Ether suitable for use in antiperspirants and deodorants, contributing to the overall formulation and feel of the product.
PPG-20 Methyl Glucose Ether's mild and conditioning properties make it suitable for use in baby care products, such as baby lotions or mild cleansers.

Safety profile:
PPG-20 Methyl Glucose Ether is generally considered a safe ingredient for use in a variety of different products within the cosmetic industry.
PPG-20 methyl glucose ether is well tolerated by most skin and hair types and is also non-comedogenic. Patch testing is not typically necessary for this ingredient.
Additionally, PPG-20 Methyl Glucose Ether is vegan and halal, making it a suitable ingredient for those following a vegan or halal lifestyle.

As with any cosmetic ingredient, it is important to use products containing PPG-20 Methyl Glucose Ether as directed and discontinue use if any signs of irritation or allergic reaction occur.
Some individuals may be more sensitive to certain cosmetic ingredients, and skin irritation or allergic reactions could occur.
PPG-20 methyl glucose ether's always advisable to perform a patch test before using a new product extensively, especially if you have a history of skin allergies or sensitivities.

Avoid contact with eyes.
In case of accidental contact, rinse thoroughly with water.
While inhalation exposure is unlikely in typical cosmetic use, excessive inhalation of fine particles or aerosols should be avoided.

The safety of any cosmetic product depends on the entire formulation, including the combination of ingredients and their concentrations.
Always follow product usage instructions and guidelines provided by the manufacturer.

P-PHENYLENEDIAMINE
chlorocresol (p-chloro-m-cresol)
PPS (POTASSIUM PERSULFATE)
PPS (Potassium Persulfate) appears as a white, fine crystalline, odorless salt with 270.33 g/mol of molar mass.
PPS (Potassium Persulfate) is the inorganic compound with the formula K2S2O8.
PPS (Potassium Persulfate) is also known as potassium peroxydisulfate or KPS, it is a white solid that is sparingly soluble in cold water, but dissolves better in warm water.


CAS Number: 7727-21-1
EC Number: 231-781-8
MDL number: MFCD00011386
Linear Formula: K2S2O8


Potassium Persulfate is a white crystalline, odourless salt with the density of 2.477.
PPS (Potassium Persulfate) can be decomposed about 100℃ and dissolved in the water and has strong oxidation.
PPS (Potassium Persulfate) has the particular advantage of being almost non-hygroscopic of having a good storage stability in normal temperature and of being easy and safe to handle.


PPS (Potassium Persulfate) is a powerful oxidant, commonly used to initiate polymerizations.
PPS (Potassium Persulfate) enhances the free flowing properties and tends to lumping.
PPS (Potassium Persulfate) has the particular advantage of being only slightly hygroscopic and easy and safe to handle.


As a result of the process used for PPS (Potassium Persulfate)'s production it is free from contamination by ammonium ions.
Due to its extremely high purity PPS (Potassium Persulfate) has a good storage stability.
PPS (Potassium Persulfate) is the inorganic compound with the formula K2S2O8.


PPS (Potassium Persulfate) is also known as potassium peroxydisulfate or KPS, it is a white solid that is sparingly soluble in cold water, but dissolves better in warm water.
PPS (Potassium Persulfate) is non-inflammable, but it can help combustion due to the release of oxygen.


When stored, PPS (Potassium Persulfate) must be stored in a dry, closed container, away from direct sunlight and near heat sources.
Do not come in contact with reducing substances such as organic matter, rust, or trace metals to prevent decomposition or explosion of PPS (Potassium Persulfate).
PPS (Potassium Persulfate) is a white, finely crystalline, odourless salt consisting of technically pure potassium peroxydisulfate and silicic acid to enhance the free flowing properties.


PPS (Potassium Persulfate) has the particular advantage of being only slightly hygroscopic and easy and safe to handle.
As a result of PPS (Potassium Persulfate)'s extremely high purity it has a good storage stability.
Due to PPS (Potassium Persulfate)'s fine crystallinity potassium peroxydisulfate tends to lumping.


PPS (Potassium Persulfate) almost does not absorb moisture, it is easy to store, easy to use and safe.
PPS (Potassium Persulfate) is the inorganic compound with the formula K2S2O8.
PPS (Potassium Persulfate) is also known as potassium peroxydisulfate, it is a white solid that is sparingly soluble in cold water, but dissolves better in warm water.


PPS (Potassium Persulfate) is a powerful oxidant, commonly used to initiate polymerizations.
PPS (Potassium Persulfate) appears as a white crystalline solid. PPS (Potassium Persulfate)'s specific gravity 2.477.
PPS (Potassium Persulfate)'s decomposes is below 100 °C.


PPS (Potassium Persulfate) is soluble in water.
PPS (Potassium Persulfate) is insoluble in alcohol.
PPS (Potassium Persulfate) is an inorganic compound that is a strong oxidant.


PPS (Potassium Persulfate) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
PPS (Potassium Persulfate) decomposes completely at 100 oC.


PPS (Potassium Persulfate) is slightly soluble in water.
PPS (Potassium Persulfate) is not flammable.
PPS (Potassium Persulfate) should be stored in closed, cool and dry places.


PPS (Potassium Persulfate) should be protected from heat and moisture.
PPS (Potassium Persulfate) is not harmful to health as crystal and solution when studied carefully.
PPS (Potassium Persulfate), also known as potassium peroxydisulfate is a chemical compound used as an oxidizing agent, with the formula K2S2O8.


PPS (Potassium Persulfate) is a transparent colorless crystal that is a strong oxidizer.
PPS (Potassium Persulfate) is generally immediately available in most volumes.
PPS (Potassium Persulfate) is a strong oxidizing agent and is incompatible with organic compounds.


PPS (Potassium Persulfate) is colorless or white crystals.
PPS (Potassium Persulfate) has no odor.
PPS (Potassium Persulfate) is soluble in about 50 parts of water, 25 parts of 40 deg C water, aqueous solution is acidic.


PPS (Potassium Persulfate) is insoluble in ethanol.
The gradual decomposition of PPS (Potassium Persulfate) in air releases oxygen, and the decomposition is faster at high temperature, and the total decomposition is at 100.
PPS (Potassium Persulfate) is also a raw material for the preparation of hydrogen peroxide.


PPS (Potassium Persulfate), also known as high potassium sulfate, molecular weight: 270.32, decomposition temperature: 50-60 ℃, is a white, tasteless Crystal, soluble in water, insoluble in ethanol, with strong oxidation, commonly used as bleach, oxidant.
PPS (Potassium Persulfate) is the inorganic compound with the formula K2S2O8.


PPS (Potassium Persulfate) is also known as potassium peroxydisulfate or KPS, it is a white solid that is highly soluble in water.
PPS (Potassium Persulfate) is a powerful oxidant, commonly used to initiate polymerizations.
PPS (Potassium Persulfate) is also known as potassium peroxydisulfate or KPS, it is a white solid that is sparingly soluble in cold water, but dissolves better in warm water.



USES and APPLICATIONS of PPS (POTASSIUM PERSULFATE):
PPS (Potassium Persulfate) acts as an initiator for the polymerization of monomers of acrylic, vinyl acetate, vinyl chloride etc. and for the emulsion co-polymerization of styrene, acrylonitrile, butadiene etc. in combination with the redox systems and as a strong oxidizing agent in many applications.
Others uses of PPS (Potassium Persulfate): chemical synthesis.


PPS (Potassium Persulfate) is used as Water treatment (purification).
PPS (Potassium Persulfate) is used Waste gas treatment, oxidative degradation of harmful substances (e.g. mercury).
PPS (Potassium Persulfate) is used as Disinfectant


PPS (Potassium Persulfate) is used as an initiator (source of free radicals) for the polymerisation of monomers and as a strong oxidising agent in many applications.
As a result of the process used for its production PPS (Potassium Persulfate) is free from contamination by ammonium ions.
PPS (Potassium Persulfate) is used as an oxidizing agent in organic synthesis.


PPS (Potassium Persulfate) is involved in the Elbs persulfate oxidation of phenols and the Boyland-Sims oxidation of anilines.
In solution, PPS (Potassium Persulfate) gives radicals and is used to initiate polymerization reactions to prepare styrene-butadiene rubber and polytetrafluoroethylene.
PPS (Potassium Persulfate) is used as a bleaching agent in various hair bleaches, as an ion exchange agent, a plating agent and a surface treating agent.


PPS (Potassium Persulfate) is used as an oxidizing agent in organic synthesis.
PPS (Potassium Persulfate) is involved in the Elbs persulfate oxidation of phenols and the Boyland-Sims oxidation of anilines.
In solution, PPS (Potassium Persulfate) gives radicals and is used to initiate polymerization reactions to prepare styrene-butadiene rubber and polytetrafluoroethylene.


PPS (Potassium Persulfate) is used as a bleaching agent in various hair bleaches, as an ion exchange agent, a plating agent and a surface treating agent.
PPS (Potassium Persulfate) is used in organic reactions for polymerization.
PPS (Potassium Persulfate) is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


PPS (Potassium Persulfate) is used in the following products: cosmetics and personal care products and perfumes and fragrances.
Other release to the environment of PPS (Potassium Persulfate) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).


PPS (Potassium Persulfate) is used in the following products: cosmetics and personal care products, pH regulators and water treatment products and laboratory chemicals.
PPS (Potassium Persulfate) is used in the following areas: health services and scientific research and development.
Other release to the environment of PPS (Potassium Persulfate) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as reactive substance.


PPS (Potassium Persulfate) is used in the following products: pH regulators and water treatment products and laboratory chemicals.
Release to the environment of PPS (Potassium Persulfate) can occur from industrial use: formulation of mixtures.
PPS (Potassium Persulfate) is used in the following products: oil and gas exploration or production products, pH regulators and water treatment products and laboratory chemicals.


PPS (Potassium Persulfate) is used in the following areas: health services and scientific research and development.
PPS (Potassium Persulfate) is used for the manufacture of: chemicals.
Release to the environment of PPS (Potassium Persulfate) can occur from industrial use: as processing aid, in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.


Release to the environment of PPS (Potassium Persulfate) can occur from industrial use: manufacturing of the substance.
PPS (Potassium Persulfate) is used in the polymerization of acrylonitrile, generally in the production of polyacrylonitrile fiber together with alkali sulfides, in the polymerization of various monomers; as an oxidant in the textile industry; in the oxidation of sulfur dyes; in metal, photography, cosmetics industries; in the production of various chemicals; purification of ammonium sulfate; as an antiseptic.


PPS (Potassium Persulfate) is used in soap production and medicine production.
PPS (Potassium Persulfate) is the initiator of latex or solution polymerization of acrylic monomers, vinyl acetate, vinyl chloride and other product, but also the initiator of styrene, acrylonitrile, butadiene and similar emulsion for copolymerization.


PPS (Potassium Persulfate)is mainly used as initiator and strong oxidizing agents
PPS (Potassium Persulfate) is used as a desizing agent and bleach activator.
PPS (Potassium Persulfate) is used for oxidative degradation of harmful substances in the pool and closed circular cycle in the water.


PPS (Potassium Persulfate) can be applied in the production of starch modifier and applied in the production of adhesive and coating agent.
PPS (Potassium Persulfate) is used applicable to branched chain oxidation, alcohol and aromatic hydroxy oxidation.
PPS (Potassium Persulfate) is used in the polymerization of acrylonitrile, often in the production of polyacrylonitrile fibers with alkaline sulfides, in the emulsion polymerization of monomers.


PPS (Potassium Persulfate) is used as an oxidant in the textile industry.
PPS (Potassium Persulfate) is used in the oxidation of sulfur dyes.
PPS (Potassium Persulfate) is used in Metal, photography, cosmetics industries.


PPS (Potassium Persulfate) is used in the production of various chemicals.
PPS (Potassium Persulfate) is used as an analytical reagent for the determination of manganese content in steel analysis.
PPS (Potassium Persulfate) is also used as a disinfectant, a fabric bleaching agent, a sodium thiosulfate remover and a deodorizing agent.


PPS (Potassium Persulfate) is used as an oxidant for dyes and inorganic salts in chemical reactions.
PPS (Potassium Persulfate) is used as an initiator for elastomer in synthetic rubber.
PPS (Potassium Persulfate) is used as an accelerator for polyvinyl chloride emulsion polymerization in the production of synthetic resin.


Applications of PPS (Potassium Persulfate) include: polymerization initiators, circuit board cleaning and etching, copper and aluminum surface activation, starch modification, low temperature bleaching and Desizing of pulp and fabrics, purification of circulating water systems, oxidative degradation of harmful gases, low formaldehyde adhesive adhesion acceleration, ethanol and aromatic hydrocarbon oxidation, disinfectant, hair dye decolorization.


PPS (Potassium Persulfate) can also be used as a polymerization initiator, which hardly absorbs moisture, has good stability at room temperature, is convenient for storage, and has the advantages of convenience and safety.
PPS (Potassium Persulfate) is used to initiate polymerization of various alkenes leading to commercially important polymers such as styrene-butadiene rubber and polytetrafluoroethylene and related materials.


In solution, the dianion dissociates to give radicals:
[O3SO-OSO3]2− 2 [SO4]•−
PPS (Potassium Persulfate) is used in organic chemistry as an oxidizing agent, for instance in the Elbs persulfate oxidation of phenols and the Boyland–Sims oxidation of anilines.


As a strong yet stable bleaching agent PPS (Potassium Persulfate) also finds use in various hair bleaches and lighteners.
Such brief and non-continuous use is normally hazard free, however prolonged contact can cause skin irritation.
PPS (Potassium Persulfate) has been used as an improving agent for flour with the E number E922, although it is no longer approved for this use within the EU.


PPS (Potassium Persulfate) is used Initiator for the emulsion or solution Polymerization of acrylic monomers, vinyl acetate, vinyl chloride etc. and for the emulsion co-polymerization of styrene, acrylonitrile, butadiene etc.
PPS (Potassium Persulfate) is used Oxidizing agent, used in cleaning and pickling of metal surfaces, accelerated curing of low formaldehyde adhesives and modification of starch, production of binders and coating materials.


Desizing agent and bleach activator, PPS (Potassium Persulfate) is an essential component of bleaching formulations for hair cosmetics.
PPS (Potassium Persulfate) is used as a laboratory oxidant and photography chemical.
PPS (Potassium Persulfate) is used in bleaching fabrics, soaps; in photography under the name Anthion to remove last traces of thiosulfate from plates and paper; as an oxidizing agent in analytical chemistry.


PPS (Potassium Persulfate) is often used as a strong oxidant, and also as an initiator of monomer polymerization.
PPS (Potassium Persulfate) is used to initiate polymerization of various alkenes leading to commercially important polymers such as styrene-butadiene rubber and polytetrafluoroethylene and related materials.


In solution, the dianion dissociates to give radicals:
[O3SO-OSO3]2− ⇌ 2 [SO4]•−
PPS (Potassium Persulfate) is used in organic chemistry as an oxidizing agent, for instance in the Elbs persulfate oxidation of phenols and the Boyland–Sims oxidation of anilines.


As a strong yet stable bleaching agent PPS (Potassium Persulfate) also finds use in various hair bleaches and lighteners.
PPS (Potassium Persulfate) has been used as an improving agent for flour with the E number E922, although it is no longer approved for this use within the EU.
PPS (Potassium Persulfate) is a suitable initiaor for the emulsion or solution polymerisation of acrylic monomers, vinyl acetate, vinyl chloride etc. and for the emulsion copolymerisation of styrene, acrylonitrile, butadiene etc.


PPS (Potassium Persulfate) is also a kind of oxidizing agent.
PPS (Potassium Persulfate) is used in cleaning and pickling of metal surfaces.
PPS (Potassium Persulfate) is used in accelerated curing of low formaldehyde adhesives.


PPS (Potassium Persulfate) is used in modification of starch, production of binders and coating materials.
PPS (Potassium Persulfate) is used Desizing agent and bleach activator.
PPS (Potassium Persulfate) is used an essential component of bleaching formulations for hair cosmetics.


PPS (Potassium Persulfate) is mainly used as a disinfectant and fabric bleach.
Industrial dyes and inorganic salts, PPS (Potassium Persulfate) is used as the oxidant.
PPS (Potassium Persulfate) is used Synthetic rubber industry as emulsion polymerization initiators.


Synthetic resin, PPS (Potassium Persulfate), is used as a polymerization accelerator.
In addition, the terms used in the steel, photographic industry and medicine.
PPS (Potassium Persulfate) is used to initiate polymeriziation of various alkenes leading to commercially important polymers such as styrene-butadiene rubber and polytetrafluoroethylene and related materials.


In solution, the dianion dissociates to give radicals: [O3SO-OSO3]2− ⇌ 2 [SO4]−
PPS (Potassium Persulfate) is used in organic chemistry as an oxidizing agent, for instance in the Elbs persulfate oxidation of phenols and the Boyland–Sims oxidation of anilines.


As a strong yet stable bleaching agent PPS (Potassium Persulfate) also finds use in various hair bleaches and lighteners.
PPS (Potassium Persulfate) has been used as an improving agent for flour with the E number E922, although it is no longer approved for this use within the EU.
PPS (Potassium Persulfate) is used to initiate polymerziation of various alkenes leading to commercially important polymers such as styrene-butadiene rubber and polytetrafluoroethylene and related materials.


PPS (Potassium Persulfate) is used to make soap (bleaching), promote polymerization, condition flour, and modify starch.
PPS (Potassium Persulfate) is also used as a reducing agent in photography, a desizing agent in textiles, and an oxidizing agent for dyes.
PPS (Potassium Persulfate) is a powerful oxidant, commonly used to initiate polymerizations.


-Cosmetics:
PPS (Potassium Persulfate) is used the main ingredient of bleaching formula.
-Textiles:
PPS (Potassium Persulfate) is used desizing and bleaching agents - especially for low temperature bleaching.


-Polymerization:
PPS (Potassium Persulfate) is used initiator of latex or acrylic monomer polymerization liquid, vinyl acetate, vinyl chloride and other products, and initiator of copolymerization of styrene, acrylonitrile, butadiene and other colloid.


-Metal treatment:
PPS (Potassium Persulfate) is used treatment of metal surfaces (e.g. in semiconductor manufacturing: cleaning and etching of printed circuits).
PPS (Potassium Persulfate) is used as an activation of copper and aluminum surfaces.


-Polymerization:
PPS (Potassium Persulfate) is used as initiator of latex or acrylic monomer polymerization solution, initiator of ethyl acetate, ethylene chloride, vinyl chloride and other products.
PPS (Potassium Persulfate) is also an initiator of copolymerization of styrene acrylonitrile, butadiene and other colloids.


-Metal treatment:
PPS (Potassium Persulfate) is used Treatment of metal surfaces (eg in semiconductor manufacturing: cleaning and etching of printed circuits).
PPS (Potassium Persulfate) is used Activation of copper and aluminum surfaces.


-Cosmetics:
PPS (Potassium Persulfate) is used The main ingredient in bleaching formulas.
-Textiles:
PPS (Potassium Persulfate) is used De-slurry and bleach - especially for low-temperature bleaching.


-Others uses of PPS (Potassium Persulfate): Chemical synthesis: Water treatment (purification); Disinfectant; Exhaust gas treatment, oxidative degradation of harmful substances (eg mercury).
-TEXTILE:
PPS (Potassium Persulfate) is desizing agent and bleach activator - particularly for cold bleaching (e.g. bleaching of jeans).


-POLYMERIZATION:
Initiator for the emulsion or solution polymerization of acrylic monomers, vinyl acetate, vinyl chloride etc. and for the emulsion copolymerization of styrene, acrylonitrile, butadiene etc.
In combination with redox systems (ascorbic acid, Rongalite, sulfites or sugar - possibly in combination with heavy metal salts such as Fe2+) PPS (Potassium Persulfate) can also be used for polymerization reactions carried out at lower - and even at ambient - temperatures.
To reduce the residual monomer content, a combination of
PPS (Potassium Persulfate) with TBHP-70-AQ is recommended, particularly in cases where redox systems are used.


-COSMETICS:
PPS (Potassium Persulfate) is essential component of bleaching formulations
-PAPER:
PPS (Potassium Persulfate) is modification of starch; repulping particularly of wet-strength paper


-Other uses of PPS (Potassium Persulfate):
*chemical synthesis
*water treatment (decontamination)
*waste gas treatment; oxidative degradation of harmful substances (e.g. Hg)


-polymerization:
PPS (Potassium Persulfate) is used initiator for the emulsion or solution Polymerization of acrylic monomers, vinyl acetate, vinyl chloride etc. and for the emulsion co-polymerization of styrene, acrylonitrile, butadiene etc.


-PPS (Potassium Persulfate) is mainly used for initiator and strong oxidant initiator: PPS (Potassium Persulfate) is latex or acrylic monomer polymerization liquid, vinyl acetate, the initiator of vinyl chloride and other products is also the initiator of the copolymerization of styrene, acrylonitrile, butadiene and Other colloids.


-Metal treatment:
PPS (Potassium Persulfate) is used Treatment of metal surfaces(e.g. in the manufacture of semiconductors; cleaning and etching of printed circuits), activation of copper and aluminium surfaces.


-Cosmetics:
PPS (Potassium Persulfate) is used as an essential component of bleaching formulations.
-Paper:
PPS (Potassium Persulfate) is used a modification of starch,repulping of wet - strength paper.
-Textile:
PPS (Potassium Persulfate) is a used desizing agent and bleach activator - particularly for cold bleaching.(i.e.bleaching of Jeans).


-Others uses of PPS (Potassium Persulfate):
*Chemical synthesis
*Water treatment(decontamination)
*Waste gas treatment,oxidative degradation of harmful substances(e.g.Hg)
*Disinfectant


-Strong oxidants:
PPS (Potassium Persulfate) is used as Desizing agent and bleach activator.
PPS (Potassium Persulfate) is used for the oxidation and degradation of harmful substances in water pool and closed cycle treatment.
PPS (Potassium Persulfate) is the production of starch regulator, and used in the production of adhesives and coatings.
PPS (Potassium Persulfate) is used for branched-chain oxidation, ethanol and aromatic hydroxyl oxidation.
PPS (Potassium Persulfate) is one of the basic components of the hair dye, the role of decolorization.



KEY FEATURES OF PPS (POTASSIUM PERSULFATE):
Key Features of PPS (Potassium Persulfate):
These PPS (Potassium Persulfate) is a white, crystalline, odourless salt.
PPS (Potassium Persulfate) is used as initiator for the polymerisation of monomers and as a strong oxidizing agent in many application.

PPS (Potassium Persulfate) has the particular advantage of being almost non-hygroscopic, of having a particularly good storage stability as a result of its extremely high purity and of being easy and safe to handle.
PPS (Potassium Persulfate) is a suitable initiaor for the emulsion or solution polymerisation of acrylic monomers, vinyl acetate, vinyl chloride etc. and for the emulsion copolymerisation of styrene, acrylonitrile, butadiene etc..

PPS (Potassium Persulfate) is also a kind of oxidizing agent:
(1) Used in cleaning and pickling of metal surfaces.
(2) Used in accelerated curing of low formaldehyde adhesives.
(3) Used in modification of starch, production of binders and coating materials.
(4) Desizing agent and bleach activator.
(5) An essential component of bleaching formulations for hair cosmetics.
PPS (Potassium Persulfate) is a kind of white tasteless crystal or powder, which is decomposed by ethanol and has good stability at room temperature.



CHEMICAL PROPERTIES OF PPS (POTASSIUM PERSULFATE):
When PPS (Potassium Persulfate) is heated in a 50% aqueous solution of sulfuric acid, hydrogen peroxide results, which, due to the high temperature, distills from the solution.
The H2O2 obtained this way has a concentration of 40-60%.
This method was previously used in the manufacturing of hydrogen peroxide on industrial scale before being replaced by the quinone process.

PPS (Potassium Persulfate) will react with silver nitrate to form silver(I,III) oxide (silver peroxide):
K2S2O8 + AgNO3 → Ag4O4 + K2SO4 + SOx + NOx + Ox
PPS (Potassium Persulfate) oxidizes acetone in the presence of diluted sulfuric acid and silver metal to acetic acid, releasing carbon dioxide:

2 K2S2O8 + (CH3)2CO → CH3COOH + KHSO4 + CO2
Reaction with nitric acid gives off oxygen and ozone fumes, and nitrogen as byproduct.
Heating PPS (Potassium Persulfate) in solution or slush to 80-90 Celsius for 2-3 minutes in presence of MnO2 leads to a decomposition reaction catalyzed by manganese dioxide:

2 K2S2O8 + 2H2O → 4 KHSO4 + O2
This reaction can be used as a qualitative test for the peroxodisulfate anion: just heat it with MnO2 and check the pH with a test strip.
Low pH means positive test.



PHYSICAL PROPERTIES OF PPS (POTASSIUM PERSULFATE):
PPS (Potassium Persulfate) is a white crystalline solid, poorly soluble in water.
PPS (Potassium Persulfate) decomposes if heated to temperatures over 125°C.
PPS (Potassium Persulfate) has a density of 2.477 g/cm3.



STRUCTURE OF PPS (POTASSIUM PERSULFATE):
The sodium and potassium salts are very similar.
In the potasium salt, the O-O distance is 1.495 Å.
The individual sulfate groups are tetrahedral, with three short S-O distances near 1.43 and one long S-O bond at 1.65 Å.



RAW MATERIALS OF PPS (POTASSIUM PERSULFATE):
Ammonium persulfate
Sulfuric acid
Ammonium sulfate
Potassium Sulphate



PREPARATION OF PPS (POTASSIUM PERSULFATE):
The most common way to synthesize PPS (Potassium Persulfate) is via the electrolysis of a cold solution potassium bisulfate in sulfuric acid, at a high current density:
2 KHSO4 → K2S2O8 + H2
Tantalum electrodes can be used in this reaction.

Bubbling elemental fluorine through an aqueous solution of KHSO4 or K2SO4 will also yield PPS (Potassium Persulfate).
The reaction also works in the absence of water.
PPS (Potassium Persulfate) can also be prepared by adding KHSO4 to a solution of the more soluble salt ammonium peroxydisulfate.
PPS (Potassium Persulfate) will precipitate from this reaction.

PPS (Potassium Persulfate) can be prepared by electrolysis of a cold solution potassium bisulfate in sulfuric acid at a high current density.
2 KHSO4 → K2S2O8 + H2
ItPPS (Potassium Persulfate)to a solution of the more soluble salt ammonium peroxydisulfate (NH4)2S2O8.
In principle PPS (Potassium Persulfate) can be prepared by chemical oxidation of potassium sulfate using fluorine.
Several million kilograms of the ammonium, sodium, and potassium salts of peroxydisulfate are produced annually.

Ammonium persulfate was dissolved in water, and potassium hydroxide solution was added.
The mixture was heated under aeration until ammonia was depleted.
After cooling, Suction filtration crystallization, washing, drying to obtain PPS (Potassium Persulfate).



RECRYSTALIZATION OF PPS (POTASSIUM PERSULFATE):
PPS (Potassium Persulfate) was dissolved in water at 30 °c and cooled to obtain a recrystallized product, which was filtered and dried under reduced pressure in the presence of calcium chloride.



PHYSICAL and CHEMICAL PROPERTIES of PPS (POTASSIUM PERSULFATE):
Molecular Weight: 270.32
Molecular Weight : 270.3 kg/kmol
Specific Gravity : 2,480 kg/m³
pH Value (%5 solution) : 3-7
Thermal Decomposition : ≥65°C
Solubility in Water : 6(25 °C) 17(50 °C) (g/100 g H2O)
Physical state: powder
Color: white
Odor: odorless
Melting point/freezing point:
Melting point: 100 °C
Initial boiling point and boiling range: No data available
Flammability (solid, gas): The product is not flammable.
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: > 600 °C

Decomposition temperature: 170 °C
pH 2,5 - 4,5 at 27 g/l at 25 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 52,77 g/l at 20 °C
Partition coefficient: n-octanol/water: - Not applicable for inorganic substances
Vapor pressure: < 0,1 hPa at 25 °C
Density: 2,477 g/cm3
Relative density: 1,39 at 20 °C
Relative vapor density: 9,33 - (Air = 1.0)
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: The substance or mixture is classified as oxidizing with the category 3.
Other safety information:
Relative vapor 9,33 - (Air = 1.0)

Compound Formula: K2O8S2
Molecular Weight: 270.32
Appearance: White powder or crystals
Melting Point: N/A
Boiling Point: N/A
Density: 2.477 g/cm3
Solubility in H2O: N/A
Exact Mass: 269.830872
Monoisotopic Mass: 269.830872
Appearance: white, finely crystalline solid
Assay: (typically) ca. 99.0 % w/w
Active oxygen: (AO, typically) ca. 5.9 % w/w
Acid: (calculated as H2SO4, typically) ca. 0.05 % w/w
Iron content: (typically) ca. 1 mg/kg
Bulk density: ca. 1100 kg/m3
Melting point: (decomposition)

Solubility in water: at 10 / 20 / 40 / 60 °C ca. 30 / 50 / 105 / 210 g/L
pH of a 1 % solution in water: ca. 3.7
pH of a 10 % solution in water: ca. 3.1
Decomposition temperature: (SADT)* 170 °C
Recommended storage temperature: < 30 °C
Storage: stability as from date of delivery 12 months
Moisture content: (typically) < 0.03 % w/w
Density: 2.477 g/cm3
Melting Point: 100 °C (decomposition)
pH value: 2.5 - 4.5 (27 g/l, H₂O, 25 °C)
Vapor pressure: Bulk density: 1150 kg/m3
Solubility: 50 g/l
Molecular Weight: 270.33
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 8

Rotatable Bond Count: 1
Exact Mass: 269.8308723
Monoisotopic Mass: 269.8308723
Topological Polar Surface Area: 150 Ų
Heavy Atom Count: 12
Formal Charge: 0
Complexity: 206
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Molecular Formula: K₂O₈S₂
Appearance: White to Off-White Solid
Melting Point: No data available
Molecular Weight: 270.32
Storage: 20°C
Solubility: Water (Slightly)
Molecular Formula :K2O8S2
Molar Mass: 270.32
Density: 2.47

Melting Point: 1067 °C
Boling Point: 1689 °C
Water Solubility: 5 g/100 mL (20 ºC)
Solubility: H2O: 0.5M at20°C, clear, colorless
Vapor Presure: 0 Pa at 25℃
Vapor Density: 9.3 (vs air)
Appearance: Solid
Specific Gravity: 2.477
Color: White
Odor: Odorless
Exposure Limit: ACGIH: TWA 0.1 mg/m3
Merck: 14,7656
PH: 3.2 (50g/l, H2O, 20℃)
Storage Condition: Store at +5°C to +30°C.
Stability: Stable.
Properties: colorless or white triclinic crystal powder.
relative density: 2.477
solubility: soluble in water, solubility: 1.75g/100ml water at 0 ℃,
solubility: 5.3g/100ml water at 20 ℃.
Insoluble in alcohol.
The aqueous solution was acidic.



FIRST AID MEASURES of PPS (POTASSIUM PERSULFATE):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of PPS (POTASSIUM PERSULFATE):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up carefully.
Dispose of properly.



FIRE FIGHTING MEASURES of PPS (POTASSIUM PERSULFATE):
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of PPS (POTASSIUM PERSULFATE):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of PPS (POTASSIUM PERSULFATE):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of PPS (POTASSIUM PERSULFATE):
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available
-Incompatible materials:
No data available



SYNONYMS:
potassium persulphate
kalium persulfate
PPS(kps) Initiator
potassium per sulphate
potassium per sulfate
persulfate de potassium
potassium hydrogen persulfate
dipotassium peroxodisulfate
kps potassium persulfate
Potassium Peroxydisulfate
cas no.7721-21-1
Sodium Peroxydisulfate
Peroxydisulfuric Acid
Disodium Peroxydisulfate
POTASSIUM PERSULFATE
7727-21-1
Potassium peroxydisulfate
Anthion
Potassium peroxodisulfate
Potassium peroxydisulphate
Dipotassium peroxydisulfate
Dipotassium persulfate
potassium persulphate
Peroxydisulfuric acid, dipotassium salt
dipotassium;sulfonatooxy sulfate
MFCD00011386
6B86K0MCZC
Dipotassium peroxodisulphate
Caswell No. 700
HSDB 2638
EINECS 231-781-8
UN1492
UNII-6B86K0MCZC
EPA Pesticide Chemical Code 063602
Virkon S
potasium persulfate
potassium persuifate
Peroxydisulfuric acid (((HO)S(O)2)2O2) , dipotassium salt
potassium monopersulphate
potassium peroxidisulfate
EC 231-781-8
DIPOTASSIUM PERSULPHATE
CHEMBL3186858
DTXSID4029690
POTASSIUM PERSULFATE [MI]
DIPOTASSIUM PEROXYDISULPHATE
dipotassium dioxidan-2-idesulfonate
Tox21_200798
AKOS015950646
NSC 326763
Potassium persulfate, ACS Reagent Grade
NCGC00258352-01
BP-13445
CAS-7727-21-1
FT-0689072
Potassium peroxydisulfate, low nitrogen, ACS
Potassium persulfate [UN1492] [Oxidizer]
dipotassium [(sulfonatoperoxy)sulfonyl]oxidanide
Potassium persulfate, Trace metals grade 99.99%
Q415226
Peroxydisulfuric acid (((HO)S(O)2)2O2), potassium salt (1:2)
Anthion
Dipotassium peroxodisulfate
Dipotassium peroxydisulfate
Dipotassium persulfate
F 210 Hygisept
Potassium dipersulfate
Potassium peroxydisulfate
Potassium peroxydisulfate (K2(S2O8))
Potassium Peroxydisulphate
Potassium persulfate
Virkon S
anthion
BETZ 2701
NP A SOLUTION
Potassium persulfate
POTASSIUM PERSULFATE
Potassium persulphate
dipotassiumpersulfate
Potassium peroxodisulfate
POTASSIUM PEROXODISULFATE
Potassium peroxydisulfate
POTASSIUM PEROXYDISULFATE
POTASSIUM PEROXYDISULPHATE
DIPOTASSIUM PEROXYDISULFATE
dipotassium peroxodisulphate
DI-POTASSIUM PEROXODISULPHATE
POTASSIUM PERSULFATE, PURIFIED
TNP-201 DECOMPOSITION SOLUTION 1
Peroxydisulfuricacid,dipotassiumsalt
dipotassium [(sulfonatoperoxy)sulfonyl]oxidanide
peroxydisulfuricacid([(ho)s(o)2]2o2),dipotassiumsalt
Peroxydisulphuric acid dipotassium salt~Potassium peroxydisulphate
Dipotassium disulfate
Potassium peroxodisulfate
Dipotassium [(sulfonatoperoxy)sulfonyl]oxidanide
Dipotassium peroxodisulphate
dipotassium sulfonatooxy sulfate
Peroxydisulfuric acid (((HO)S(O)2)2O2), dipotassium salt
Peroxydisulfuric acid dipotassium salt
Peroxydisulfuric acid, dipotassium salt
Anthion; Dipotassium peroxydisulfate
Dipotassium persulfate
Peroxydisulfuric acid (((HO)S(O)2)2O2), dipotassium salt
Potassium peroxydisulfate
Potassium peroxydisulfate (K2(S2O8))
Potassium peroxydisulphate
UN1492


PPSOH (PYRIDINIUM HYDROXY PROPYL SULFOBETAINE)
PPSOH (Pyridinium hydroxy propyl sulfobetaine) has good light and leveling effect in electronickelling, especially good high current density region leveling effect spy.
PPSOH (Pyridinium hydroxy propyl sulfobetaine) can be used to prepare electroplating brightener and nickel plating strong leveling agent.
PPSOH (Pyridinium hydroxy propyl sulfobetaine) is a kind of electroplating intermediate, and sterling is white crystal, commonly content between 40%-50%, it is colourless to weak yellow liquid.

CAS: 3918-73-8
MF: C8H11NO4S
MW: 217.24
EINECS: 223-485-2

Synonyms: 3918-73-8;2-Hydroxy-3-(pyridin-1-ium-1-yl)propane-1-sulfonate;1-(2-Hydroxy-3-sulphonatopropyl)pyridinium;2-hydroxy-3-pyridin-1-ium-1-ylpropane-1-sulfonate
1-(2-Hydroxy-3-sulfopropyl)-pyridinium betane;PPS-OH;Pyridinium, 1-(2-hydroxy-3-sulfopropyl)-, inner salt;Pyridinium hydroxy propyl sulfobetaine;1-(2-Hydroxy-3-sulfopropyl)-pyridinium betaine;EINECS 223-485-2;2-Hydroxy-1-(1-pyridyl)-3-propanesulfonate;SCHEMBL9074655;DTXSID001014636;Pyridinium, 1-(2-hydroxy-3-sulfopropyl)-, hydroxide, inner salt;MFCD00507613;AKOS015912941;SB55149;AS-69228;FT-0605544;Pyridinium-N-(2-hydroxy)propane-3-sulfonic acid;2-hydroxy-3-(pyridinium-1-yl)propane-1-sulfonate;A824446;W-106453;1-(2-HYDROXY-3-SULFONATOPROPYL)PYRIDIN-1-IUM;1-(2-HYDROXY-3-SULFOPROPYL)-PYRIDINIUMBETAINE;2-hydroxy-3-(1-pyridin-1-iumyl)-1-propanesulfonate;2-oxidanyl-3-pyridin-1-ium-1-yl-propane-1-sulfonate;68928-53-0

PPSOH (Pyridinium hydroxy propyl sulfobetaine) Chemical Properties
Boiling point: 111°C
Density: 1.30
Vapor pressure: 0Pa at 25℃
Storage temp.: 2-8°C
Water Solubility: 1280g/L at 23℃
InChI: InChI=1S/C8H11NO4S/c10-8(7-14(11,12)13)6-9-4-2-1-3-5-9/h1-5,8,10H,6-7H2
InChIKey: RJPRZHQPROLZRW-UHFFFAOYSA-N
LogP: -2 at 24℃
CAS DataBase Reference: 3918-73-8(CAS DataBase Reference)
EPA Substance Registry System: PPSOH (Pyridinium hydroxy propyl sulfobetaine) (3918-73-8)

Application
1. PPSOH (Pyridinium hydroxy propyl sulfobetaine) is a good nickel plating intermediate which has good leveling power in middle and low current density areas as PPS.
2. PPSOH (Pyridinium hydroxy propyl sulfobetaine) also has an outstanding LCD throwing power, which should be used in combination with BEO, PME, PESS, MOSS,saccharin or auxiliary brighteners.
PPS-OH (PYRIDINIUM HYDROXY PROPYL SULFOBETAINE)
PPS-OH (Pyridinium hydroxy propyl sulfobetaine) is a kind of electroplating intermediate, and sterling is white crystal, commonly content between 40%-50%.
PPS-OH (Pyridinium hydroxy propyl sulfobetaine) is colourless to weak yellow liquid.
PPS-OH (Pyridinium hydroxy propyl sulfobetaine) is used to formulate brightener additives employed in the electroplating industry, especially as a nickel plating intermediate.

CAS: 3918-73-8
MF: C8H11NO4S
MW: 217.24
EINECS: 223-485-2

PPS-OH (Pyridinium hydroxy propyl sulfobetaine) is a good nickel plating intermediate which has good leveling power in middle and low current density areas as PPS.
PPS-OH (Pyridinium hydroxy propyl sulfobetaine) also has an outstanding LCD throwing power, which should be used in combination with BEO, PME, PESS, MOSS.
PPS-OH (Pyridinium hydroxy propyl sulfobetaine) is a kind of electroplating intermediate, and sterling is white crystal, commonly content between 40%-50%, it is colourless to weak yellow liquid.

PPS-OH (Pyridinium hydroxy propyl sulfobetaine) Chemical Properties
Boiling point: 111°C
Density: 1.30
Vapor pressure: 0Pa at 25℃
Storage temp.: 2-8°C
Water Solubility: 1280g/L at 23℃
InChI: InChI=1S/C8H11NO4S/c10-8(7-14(11,12)13)6-9-4-2-1-3-5-9/h1-5,8,10H,6-7H2
InChIKey: RJPRZHQPROLZRW-UHFFFAOYSA-N
SMILES: C([N+]1=CC=CC=C1)C(O)CS([O-])(=O)=O
LogP: -2 at 24℃
CAS DataBase Reference: 3918-73-8(CAS DataBase Reference)
EPA Substance Registry System: PPS-OH (Pyridinium hydroxy propyl sulfobetaine) (3918-73-8)

Uses
PPS-OH (Pyridinium hydroxy propyl sulfobetaine) can be used to prepare electroplating brightener and nickel plating strong leveling agent.
PPS-OH (Pyridinium hydroxy propyl sulfobetaine) has good light and leveling effect in electronickelling, especially good high current density region leveling effect spy.
As the base additive in nickel plating bath, PPS-OH (Pyridinium hydroxy propyl sulfobetaine)'s consumption, be 20-50g/kAH, consumption 50-500mg/L, the huge market demand.

Synonyms
3918-73-8
2-Hydroxy-3-(pyridin-1-ium-1-yl)propane-1-sulfonate
1-(2-Hydroxy-3-sulphonatopropyl)pyridinium
2-hydroxy-3-pyridin-1-ium-1-ylpropane-1-sulfonate
PPS-OH
1-(2-Hydroxy-3-sulfopropyl)-pyridinium betane
Pyridinium, 1-(2-hydroxy-3-sulfopropyl)-, inner salt
Pyridinium hydroxy propyl sulfobetaine
1-(2-Hydroxy-3-sulfopropyl)-pyridinium betaine
EINECS 223-485-2
2-Hydroxy-1-(1-pyridyl)-3-propanesulfonate
SCHEMBL9074655
DTXSID001014636
Pyridinium, 1-(2-hydroxy-3-sulfopropyl)-, hydroxide, inner salt
MFCD00507613
AKOS015912941
SB55149
AS-69228
FT-0605544
Pyridinium-N-(2-hydroxy)propane-3-sulfonic acid
2-hydroxy-3-(pyridinium-1-yl)propane-1-sulfonate
A824446
W-106453
1-(2-HYDROXY-3-SULFONATOPROPYL)PYRIDIN-1-IUM
1-(2-HYDROXY-3-SULFOPROPYL)-PYRIDINIUMBETAINE
2-hydroxy-3-(1-pyridin-1-iumyl)-1-propanesulfonate
2-oxidanyl-3-pyridin-1-ium-1-yl-propane-1-sulfonate
Praepagen HY
Polypropylene glycol 600; Methylethyl glycol; Methylethylene glycol; 1,2-Propanediol; alpha-Propylene glycol; Methyl glycol; Monopropylene glycol; PG; 1,2-Dihydroxypropane; 1,2-Propylene Glycol; 2-Hydroxypropanol; 2,3-Propanediol; Propane-1,2-diol; Trimethyl glycol; 1,2-Propylenglykol; Isopropylene glycol; cas no: 25322-69-4
Praepagen TQ
Polypropylene glycol 900; Methylethyl glycol; Methylethylene glycol; 1,2-Propanediol; alpha-Propylene glycol; Methyl glycol; Monopropylene glycol; PG; 1,2-Dihydroxypropane; 1,2-Propylene Glycol; 2-Hydroxypropanol; 2,3-Propanediol; Propane-1,2-diol; Trimethyl glycol; 1,2-Propylenglykol; Isopropylene glycol; cas no: 25322-69-4
PRAYLEV PYRO
PRAYLEV Pyro, also known as sodium acid pyrophosphate or disodium dihydrogen pyrophosphate, is a chemical compound with the formula Na2H2P2O7.
PRAYLEV Pyro consists of sodium cations (Na+) and dihydrogen pyrophosphate anions (H2P2O2−7).
PRAYLEV Pyro is a white, water-soluble solid that serves as a buffering and chelating agent, with many applications in the food industry.

CAS Number: 7758-16-9
Molecular Formula: H5NaO7P2
Molecular Weight: 201.97
EINECS Number: 231-835-0

Synonyms: 7758-16-9, Disodium diphosphate, Sodium acid pyrophosphate, Disodium dihydrogen pyrophosphate, DISODIUM PYROPHOSPHATE, H5WVD9LZUD, disodium;[hydroxy(oxido)phosphoryl] hydrogen phosphate, MFCD00014246, Disodium acid pyrophosphate, Dinatriumpyrophosphat, Disodiumpytophosphate, Dinatriumpyrophosphat [German], Disodium dihydrogen diphosphate, Disodium dihydrogenpyrophosphate, HSDB 377, Pyrophosphoric acid, disodium salt, UNII-H5WVD9LZUD, Sodium pyrophosphate (Na2H2P2O7), EINECS 231-835-0, Sodium diphosphate dibasic, disodium pyrophosphate 2-, disodium hydrogen (hydrogen phosphonatooxy)phosphonate, Grahamsches salz, Glassy sodium phosphate, DSSTox_CID_8842, sodium dihydrogendiphosphate, EC 231-835-0, DSSTox_RID_78658, DSSTox_GSID_28842, SODIUMACIDPYROPHOSPHATE, Sodium pyrophosphate, dibasic, Sodium dihydrogen pyrophosphate, CHEMBL3184949, EINECS 272-808-3, Tox21_200813, DISODIUM PYROPHOSPHATE [HSDB], DISODIUM PYROPHOSPHATE [INCI], DISODIUM PYROPHOSPHATE [VANDF], AKOS015916169, AKOS024418779, SODIUM ACID PYROPHOSPHATE [MI], Diphosphoric acid, sodium salt (1:2), SODIUM ACID PYROPHOSPHATE [FCC], NCGC00258367-01, SODIUM ACID PYROPHOSPHATE [VANDF], CAS-68915-31-1, di-sodium dihydrogen pyrophosphate anhydrous.

PRAYLEV Pyro is a polyvalent anion with a high affinity for polyvalent cations, e.g. Ca2+.
PRAYLEV Pyro is produced by heating sodium dihydrogen phosphate: 2 NaH2PO4 → Na2H2P2O7 + H2O
PRAYLEV Pyro, disodium diphosphate, acidic sodium pyrophosphate, Na2H2P2O7, Mr 221.97, d 2.31.

Its solubility in water is 13g Na2H2P2O7/100g H2O at 20 °C, and 20g at 80°C.
The pH of a 1% aqueous solution is 4.1.
The usual commercial product is the anhydrous, nonhygroscopic salt in powder form.

The pyrophosphate ion is formed by two phosphate groups linked together.
In addition to its use in food applications, disodium pyrophosphate finds utility in various industrial processes, such as in water treatment to prevent scale formation and in metal plating baths as a buffering agent.
PRAYLEV Pyro's important to note that while disodium pyrophosphate is generally recognized as safe (GRAS) by regulatory agencies when used in accordance with good manufacturing practices, excessive consumption may lead to health concerns, particularly in individuals with certain medical conditions.

Amyloid precursor protein α is an α-secretase-cleaved soluble protein that has been shown to have neuroprotective properties.
PRAYLEV Pyro is derived from amyloid precursor protein.
The protein consists of 612 amino acids.

The hexahydrate, Na2H2P2O7.6H2O, d 1.85, crystallizes from aqueous solution below 27 °C.
Several G protein-coupled receptors are known to activate α-secretase-dependent processing of APP.
PRAYLEV Pyro has neuroprotective, neurogenic and neurotrophic functions.

PRAYLEV Pyro precursor protein a also stimulates gene expression and protein expression.
PRAYLEV Pyro is a popular leavening agent found in baking powders.
PRAYLEV Pyro combines with sodium bicarbonate to release carbon dioxide: Na2H2P2O7 + NaHCO3 → Na3HP2O7 + CO2 + H2O

PRAYLEV Pyro is available in a variety of grades that affect the speed of its action.
Because the resulting phosphate residue has an off-taste, SAPP is usually used in very sweet cakes which mask the off-taste.
PRAYLEV Pyro in baking powder, New Zealand, 1950s, Disodium pyrophosphate and other sodium and potassium polyphosphates are widely used in food processing; in the E number scheme, they are collectively designated as E450, with the disodium form designated as E450(a).

In the United States, PRAYLEV Pyro is classified as generally recognized as safe (GRAS) for food use.
In canned seafood, it is used to maintain color and reduce purge during retorting.
Retorting achieves microbial stability with heat.

PRAYLEV Pyro is an acid source for reaction with baking soda to leaven baked goods.
In baking powder, it is often labeled as food additive E450.
In cured meats, it speeds the conversion of sodium nitrite to nitrite (NO−2) by forming the nitrous acid (HONO) intermediate, and can improve water-holding capacity.

PRAYLEV Pyro is also found in frozen hash browns and other potato products, where it is used to keep the color of the potatoes from darkening.
PRAYLEV Pyro can leave a slightly bitter aftertaste in some products, but "the SAPP taste can be masked by using sufficient baking soda and by adding a source of calcium ions, sugar, or flavorings.
PRAYLEV Pyro is a chemical added to foods, cosmetics, and other products.

PRAYLEV Pyro’s useful as a preservative and a flavor enhancer, among other things.
This artificial type of salt is made from the elements sodium and phosphorus.
Chemists create PRAYLEV Pyro in a lab.

They break down naturally-occurring phosphate rock and combine it with sulfuric acid and other substances.
Some foods like legumes and wheat products naturally have similar phosphates.
Processed foods usually have much higher levels of disodium phosphate as an additive.

PRAYLEV Pyro is a chemical additive and preservative.
PRAYLEV Pyro has many aliases.
PRAYLEV Pyro also is known as disodium dihydrogen diphosphate, disodium dihydrogen pyrophosphate and disodium pyrophosphate.

It also has the name sodium acid pyrophosphate.
This chemical is an odorless white powder and, because it has a valance of greater than two, it can bond to many other chemicals.
PRAYLEV Pyro can covert sodium nitrite into nitrogen dioxide.

PRAYLEV Pyro is a colorless or yellowish hydrophilic salt that is a meat preservative and an antidote for cyanide poisoning.
PRAYLEV Pyro can widen blood vessels as well.
Nitrogen dioxide is a strongly oxidizing, poisonous reddish-brown gas.

This is one area in which conversion to another substance is not needed
PRAYLEV Pyro either colors food or prevents discoloration.
PRAYLEV Pyro is used to color hot dogs in their packaging.

PRAYLEV Pyro also is used in commercially packaged hash browns to prevent the potato from oxidizing and browning.
It is a generally recognized as safe (GRAS) substance in the use of food, but there are warnings of excessive use because it may lead to imbalanced levels of minerals in the body and bone loss.
PRAYLEV Pyro is used in canned seafood to retain color and to prevent decomposition during transport from the production plant to stores.

PRAYLEV Pyro also is used as a leavening agent for different kinds of breads.
A leavening agent is a substance that acts like yeast to make bread rise.
PRAYLEV Pyro is a buffering agent and a Lewis base, a base that gives away electrons, drawing it near to other compounds.

PRAYLEV Pyro neutralizes other substances.
PRAYLEV Pyro also has industrial uses.
It can remove iron stains and stabilize hydrogen peroxide.

PRAYLEV Pyro is used to clean the machine used in dairy farms.
PRAYLEV Pyro also is used to remove hair from pigs and feathers from poultry before they are led to slaughter.
PRAYLEV Pyro is used in making plastics, too.

Phosphates like PRAYLEV Pyro are derived from the element phosphorus.
They’re used to enhance food characteristics like nutritional value and cooking performance.
PRAYLEV Pyro is used in packaged foods, including macaroni and pastas.

PRAYLEV Pyro’s also used in some cheeses as an emulsifier.
PRAYLEV Pyro is a white crystalline powder or melt.
PRAYLEV Pyro can function as an improver, pH regulator, metal ion chelating agent, binder, leavening agent, color modifier, and be used to make biscuits, bread, meat products, and to peel fruits and vegetables, etc.

It can be jointly used as a chelating agent with other phosphates and has strong water retention capacity on meat, but it cannot be used alone because it is acid.
When PRAYLEV Pyro is added to the leavening agent in a certain proportion, the emission rate of carbon dioxide can be controlled and therefore loose texture bread and pastry products are produced.
White or colorless crystalline free flowing solid, efflorescent in air, easily soluble in water, but insoluble in alcohol, its water solution is slightly alkaline, relative density at 1.52 g/cm3, melting point at 35ºC.

PRAYLEV Pyro, SAPP, can be used in leather processing to remove iron stains from raw hides during processing.
PRAYLEV Pyro, SAPP, can stabilize the hydrogen peroxide solution against reduction.
PRAYLEV Pyro / SAPP can be used with sulfamic acid for cleaning, especially soapstone removal in specific dairy.

In oil production, PRAYLEV Pyro can be used as a dispersant for oil well drilling mud.
In leather treatment, PRAYLEV Pyro /Disodium diphosphate can remove iron stains on hides during processing.
PRAYLEV Pyro /Disodium diphosphate can stabilize hydrogen peroxide solutions against reduction.

PRAYLEV Pyro can be used with sulfamic acid in some dairy applications for cleaning, es remove soapstone.
When added to scalding water, it facilitates the removal of hair and scurf in hog slaughter and feathers and scurf in poultry sla Sodium Acid Pyrophosphate can be used as a dispersant in oil well drilling muds in petroleum production.
PRAYLEV Pyro is used in cat foods as a palatability additive.

PRAYLEV Pyro is used as a tartar control agent in toothpaste.
PRAYLEV Pyro is used in industrial contexts, particularly in water treatment opera to the culinary world.
Because of its ability to sequester metal ions, it can effectively prevent corrosion and scale formation in increasing their longevity and operational efficiency.

PRAYLEV Pyro, also named sodium acid pyrophosphate, is a white powder or granular.
Relative density 1.86g/cm3; Soluble in water and insoluble in ethanol; If its aqueous solution is heated together with diluted inorganic acid, disodium dihydrogen pyrophosphate will be hydrolyzed into phosphoric acid; It is hygroscopic, and when absorbing humidity it will become into a product with hexahydrate; If sodium acid pyrophosphate is heated at a temperature above 220℃, it will be decomposed into sodium metaphosphate.

PRAYLEV Pyro, also known as sodium acid pyrophosphate (SAPP), has several applications in various industries.
PRAYLEV Pyro is widely used as a food additive in bakery products, such as bread, cakes, and pastries.
PRAYLEV Pyro acts as a leavening agent, helping to create a lighter texture by releasing carbon dioxide gas during baking.

PRAYLEV Pyro is also used in biscuits and cakes to reduce fermenting time and extend product storage.
When applied to instant noodles, it can shorten water resetting time and avoid the stickiness and mushiness of the noodles.
PRAYLEV Pyro is used as a pH regulator, emulsifier, and texture modifier in various processed food products.

PRAYLEV Pyro helps control acidity or alkalinity, improve shelf life, and enhance texture and appearance.
PRAYLEV Pyro is utilized in the meat industry as a meat tenderizer and as a color stabilizer in cured meat products, such as sausages and hams.
PRAYLEV Pyro helps improve water retention and maintain desirable color.

PRAYLEV Pyro is found in toothpaste and mouthwash.
It serves as a tartar control agent, helping to prevent the formation of tartar or dental calculus on teeth.
PRAYLEV Pyro is used in certain water treatment processes, particularly in the prevention of scale formation.

It can help inhibit the deposition of calcium and magnesium ions, reducing the potential for scaling in pipes and equipment.
PRAYLEV Pyro is employed in various industrial processes, such as metal treatment and detergent formulations.
PRAYLEV Pyro assists as a dispersing agent, chelating agent, and emulsifier in these applications.

Colorless transparent glass-like block or sheet. Soluble in water, insoluble in organic solvents.
Strong hygroscopicity, in warm water, acid or alkali solution easily hydrolyzed to orthophosphate.
Melting point 616 C (decomposition), relative density (d2020)2.484.

PRAYLEV Pyro should be stored in a dry and ventilate warehouse, kept away from moisture and hot.
Furthermore, PRAYLEV Pyro should be stored separately from poisonous substances.
Unload with care as to avoid damage to packing.

Above this temperature, PRAYLEV Pyro is converted to the anhydrous form.
PRAYLEV Pyro is used as a (tropically stable) acid carrier in baking powder, for improvement of flow properties in flour, for pH regulation, and in dental care products for prevention of tartar formation.
PRAYLEV Pyro gene is mapped to human chromosome 21q21.3.

PRAYLEV Pyro encodes a integral membrane protein.
APPα is a soluble protein generated by sequential cleavage with α and γ secretase.
PRAYLEV Pyro is a white, crystalline powder that is soluble in water.

Its chemical structure consists of two sodium ions (Na+) and a pyrophosphate ion (P2O7^4-).
When crystallized from water, it forms a hexahydrate, but it dehydrates above room temperature.
Additionally, PRAYLEV Pyro is used in various other food products like processed meats, canned seafood, and potato products to control acidity and maintain moisture.

PRAYLEV Pyro has a sodium acid pyrophosphate food grade and an appearance of hygroscopic white powder without foreign matters.
PRAYLEV Pyro is used as a leavening agent for bakery.
PRAYLEV Pyro has a sodium acid pyrophosphate food grade and an appearance of hygroscopic white powder without foreign matters.

PRAYLEV Pyro is used as a leavening agent for bakery.
PRAYLEV Pyro or sodium acid pyrophosphate (SAPP) is an inorganic compound with the chemical formula Na2H2P2O7.

PRAYLEV Pyro is commonly used in the food industry as a leavening agent, buffering agent, emulsifier, and stabilizer.
PRAYLEV Pyro helps dough rise by releasing carbon dioxide gas when mixed with water and an alkaline ingredient, such as baking soda.

Melting point: decomposes 220℃ [MER06]
Density (hexahydrate): 1.86
vapor pressure: 0Pa at 20℃
storage temp.: -70°C
solubility: H2O: 0.1 M at 20 °C, clear, colorless
form: white powder
color: White to Off-White
PH: 3.5-4.5 (20℃, 0.1M in H2O, freshly prepared)
Water Solubility: Fully miscible in water. Insoluble in alcohol and ammonia.
λmax λ: 260 nm Amax: 0.11
λ: 280 nm Amax: 0.09
Merck: 13,8643
Stability: Stable.
InChI: InChI=1S/Na.H4O7P2.H/c;1-8(2,3)7-9(4,5)6;/h;(H2,1,2,3)(H2,4,5,6);
InChIKey: IQTFITJCETVNCI-UHFFFAOYSA-N
SMILES: O(P(O)(O)=O)P(O)(O)=O.[NaH]
LogP:-3.420 (est)

PRAYLEV Pyro is a helpful emulsifier for dairy products and other foods.
Cheese, whipped cream, milk, and other dairy products have unique textures and consistencies because of disodium phosphate.
This is a chemical that helps to bind fats and water together.

Fats don’t mix with many other liquids without help.
Emulsifiers have a chemical structure that helps them mix.
Many foods have PRAYLEV Pyro-containing additives to enhance their flavor.

A food’s pH level (or level of acidity) can affect its nutritional value, color, and other characteristics.
Canning or using jars can alter foods’ pH levels.
PRAYLEV Pyro can help control a food’s pH level throughout the production process.

PRAYLEV Pyro is added to rennet casein as a food preservative and to make certain foods edible.
PRAYLEV Pyro is the lining of cattle stomach (tripe) used for curdling milk.
Casein is a phosphoprotein of milk.

PRAYLEV Pyro is produced when rennet curdles milk.
PRAYLEV Pyro also makes milk curdle or coagulate and is used as a principal substance in making cheese.
PRAYLEV Pyro ,Disodium phosphate(DSP),Trisodium phosphate(TSP) all could be used for boiler water treatment.

PRAYLEV Pyro is used as control of anode corrosion,DSP is as control of alkali corrosion ,TSP is as softer of calcium and magnesium ion precipitation.
PRAYLEV Pyro is with the largest usage.
PRAYLEV Pyro and DSP keep proper alkali value and prevent more hydroxide ion.

PRAYLEV Pyro is to prevent calcium and magnesium precipitation.
From phosphate protective film inside boiler to prevent corrosion.
PRAYLEV Pyro is adapted for water hardness more than 4mmol/L,or evaporation more than 4t/h,or water hardness less than 1.5mmol and SiO2 content more than 30%.the combination of
DSP,TSP and MSP could keep the PH value of boiler water in a best range,and together with moderate dispersing agent could control the potential settings.

The ingredients list on a package of meat or frozen food may seem riddled with strange chemicals.
Most of them have long names that sound intimidating.
PRAYLEV Pyro's disturbing to think that eating chemicals with your food, and not just the food itself — but these chemicals aren't all dangerous.

Eaten in modest amounts, chemicals like sodium acid pyrophosphate are safe.
White monoclinic crystal powder.
Its relative density is 1.86.

PRAYLEV Pyro is soluble in water, insoluble in alcohol.
It hydrolyzes to orthophosphate when heated in acid medium.
PRAYLEV Pyro is hygroscopic, forms hexahydrate in damp air, and decomposes to metaphosphate at above 220ºC

In food processing industry, PRAYLEV Pyro is used as buffering, swelling agent, chelae agent, stabilizers, emulsifier, and color improver.
PRAYLEV Pyro is stable under normal conditions but can decompose when exposed to high temperatures, releasing phosphorus oxides and sodium oxide.
Apart from its role as a leavening agent in baking, PRAYLEV Pyro is also utilized in various food products such as canned seafood to maintain color and texture, in dairy products to enhance emulsification, and in potato products to prevent discoloration and maintain texture.

In food processing, it acts as a pH regulator, helping to stabilize the acidity or alkalinity of a product.
This is crucial for maintaining the desired taste, texture, and shelf-life of foods.
While generally considered safe for consumption, PRAYLEV Pyro should be used in moderation. Excessive intake may lead to potential health risks, including disturbances in calcium metabolism.

Regulatory bodies like the FDA (Food and Drug Administration) set limits on its usage in food products to ensure safety.
Beyond food applications, disodium pyrophosphate has industrial applications as a buffering agent, emulsifier, and dispersing agent.
PRAYLEV Pyro is also employed in the synthesis of various chemicals and pharmaceuticals.

PRAYLEV Pyro, like many phosphates, can contribute to eutrophication when released into water bodies in excessive amounts.
Both sodium and phosphorus can help extend foods’ shelf life.
Some of the first instances of preserving and curing food used salt.

PRAYLEV Pyro is also helpful in canning food since it prevents metal from rusting.
Processed foods often have additives that strengthen their flavor and make them more savory.

Uses:
PRAYLEV Pyro can stabilize hydrogen peroxide solutions against reduction.
PRAYLEV Pyro can be used with sulfamic acid in some dairy applications for cleaning, especially to remove soapstone.
When added to scalding water, it facilitates removal of hair and scurf in hog slaughter and feathers and scurf in poultry slaughter.

In petroleum production, it can be used as a dispersant in oil well drilling muds.
PRAYLEV Pyro is used in cat foods as a palatability additive.
PRAYLEV Pyro is used as a buffering agent in metal plating baths to regulate pH levels and improve plating efficiency.

PRAYLEV Pyro serves as a dispersing agent in dyeing and printing processes, aiding in the even distribution of dyes and pigments on fabrics.
PRAYLEV Pyro is employed in the oil and gas industry as a component of drilling fluids to control viscosity and inhibit corrosion.
PRAYLEV Pyro may have applications in pharmaceutical formulations as a pH regulator, stabilizer, or buffering agent in certain medications and topical preparations.

PRAYLEV Pyro is used in analytical chemistry techniques for various purposes, including as a reagent in the determination of certain ions or as a calibration standard in spectroscopic methods.
PRAYLEV Pyro is used as a clay stabilizer and shale inhibitor in drilling fluids to prevent swelling and dispersion of clay particles, thus improving wellbore stability and drilling efficiency.
It finds application in the ceramics industry as a dispersing agent and flux in ceramic glazes and bodies.

PRAYLEV Pyro helps control viscosity, improve flow properties, and enhance the bonding of ceramic materials during firing.
PRAYLEV Pyro is sometimes employed in wastewater treatment processes to aid in the removal of heavy metals through precipitation or chelation, thereby reducing environmental pollution.
In the paper industry, it is utilized as a paper coating additive to improve printability, smoothness, and ink adhesion.

PRAYLEV Pyro also acts as a dispersant for pigments and fillers, enhancing the uniform distribution of particles in paper pulp.
PRAYLEV Pyro may be used in the production of construction materials such as plasterboard and cementitious products as a setting retarder or accelerator, depending on specific formulation requirements.
In addition to fire retardants, disodium pyrophosphate is incorporated into the formulation of flame-retardant textiles, coatings, and plastics to enhance their fire resistance properties and reduce the risk of ignition or spread of flames.

PRAYLEV Pyro serves as a finishing agent in textile processing to improve the hand feel, drape, and wrinkle resistance of fabrics.
PRAYLEV Pyro can also aid in the removal of sizing agents and other impurities from textiles during wet processing.
PRAYLEV Pyro is utilized in biomedical research for various applications, including cell culture media formulations, protein purification, and enzyme assays, owing to its buffering capacity and compatibility with biological systems.

PRAYLEV Pyro is used as a tartar control agent in toothpastes.
In food industry, PRAYLEV Pyro is used as rapid ferment agent, quality improver and applied as acid component of bread and cake's synthetic leavening agent.
Mixed with other phosphates can be applied to water retention of meat products, such as canned meat, cooked ham, meat can and instant noodle.

PRAYLEV Pyro is commonly used as a food additive for various purposes:
PRAYLEV Pyro helps dough rise in baking by releasing carbon dioxide gas when mixed with water and an alkaline ingredient, such as baking soda.
PRAYLEV Pyro helps control acidity and pH levels in processed foods, preventing undesirable changes in taste and texture.

PRAYLEV Pyro aids in the uniform mixing of ingredients that would otherwise separate, such as in processed cheese and sauces.
PRAYLEV Pyro helps maintain the texture, moisture, and consistency of food products, extending their shelf life.
PRAYLEV Pyro is used in water treatment processes to prevent scale formation in pipes and equipment.

It chelates calcium and magnesium ions, preventing them from precipitating and forming scale deposits.
PRAYLEV Pyro is a leavening agent, preservative, sequestrant, and buffer which is mildly acidic with a ph of 4.1.
PRAYLEV Pyro is moderately soluble in water, with a solubility of 15 g in 100 ml at 25°c.

PRAYLEV Pyro is included in household and industrial cleaning formulations as a chelating agent to bind with metal ions in hard water, improving the effectiveness of detergents and reducing scaling on surfaces.
In some applications, PRAYLEV Pyro is used as a component of fire-retardant coatings and materials due to its ability to release water molecules when exposed to heat, thereby cooling and retarding the spread of flames.

PRAYLEV Pyro is employed in electroplating processes as an additive to electrolyte solutions to help regulate pH levels and improve the quality of metal coatings by reducing defects such as pitting and burning.
In the oil and gas industry, PRAYLEV Pyro is used in well stimulation treatments to prevent the precipitation of calcium and magnesium salts, which can impede the flow of oil and gas through the reservoir.
PRAYLEV Pyro serves as a reagent in laboratory experiments and chemical analyses, particularly in protocols requiring the chelation of metal ions or the adjustment of pH levels.

PRAYLEV Pyro has historical use in photographic development processes as a buffering agent and pH regulator to control the chemical reactions involved in film and print development.
PRAYLEV Pyro Dibasic is anhydrous form, pyrophosphate salt used in buffers.
In leather treatment, PRAYLEV Pyro can be used to remove iron stains on hides during processing.

It is used in doughnuts and biscuits for its variable gas release rate during the mixing, bench action, and baking process.
PRAYLEV Pyro is used in baking powder as a leavening agent.
PRAYLEV Pyro is used in canned fish products to reduce the level of undesired struvite crystals (magnesium ammonium phosphate hexahydrate) by complexing the magnesium.

PRAYLEV Pyro is used to sequester metals in processed potatoes.
PRAYLEV Pyro is also termed sapp, sodium acid pyrophosphate, acid sodium pyrophosphate, disodium diphosphate, and disodium dihydrogen pyrophosphate.

PRAYLEV Pyro is utilized in personal care products such as toothpaste, mouthwash, and cosmetics as a buffering agent, pH adjuster, and emulsifier.
In toothpaste, PRAYLEV Pyro can help remove calcium and magnesium ions from saliva, preventing them from depositing on teeth as tartar.

Safety Profile:
An irritant to skin, eyes, and mucous membranes.
When heated to decomposition PRAYLEV Pyro emits toxic fumes of POx, and Na2O.

Poison by intravenous route.
Moderately toxic by ingestion and subcutaneous routes.


PREVENTOL BIT 20 D
PREVENTOL BIT 20 D = BENZISOTHIAZOLINONE = BIT


CAS Number: 2634-33-5
EC Number: 220-120-9
MDL Number: MFCD00127753
Chemical formula: C7H5NOS



Preventol BIT 20 D is aqueous dispersion of 1,2-Benzisothiazolin-3-one (BIT).
Preventol BIT 20 D is formaldehyde- & halogen-free, in-can preservative based on benzisothiazolinone.
Aqueous, alkaline solution of Preventol BIT 20 D.
Preventol BIT 20 D is VOC- and solvent-free.


Preventol BIT 20 D is VOC-, AOX-, formaldehyde- & solvent-free, in-can preservative based on benzisothiazolinone.
The shelf life of Preventol BIT 20 D is one year.
Preventol BIT 20 D is a water-based, solvent- and VOC-free dispersion.
Preventionol BIT 20 D is a commonly used biocide in industrial and consumer products, which possesses antimicrobial activity against gram positive and gram negative bacteria.


Preventol BIT 20 D is mainly used in packaging, adhesives, detergents, disinfectants, sunscreen lotions, paints and lubricants.
This biocide Preventol BIT 20 D does not appear to have been extensively studied and hence little data is available.
Data suggests Preventol BIT 20 D has a low aqueous solubility and is rapidly broken down in the environment.
Preventol BIT 20 D has outstanding stability combined with low volatility.
Preventol BIT 20 D is an antimicrobial agent and a pharmaceutical intermediate.


Preventol BIT 20 D is Soluble in dichloromethane, dimethyl sulfoxide, methanol.
Preventol BIT 20 D is an organic compound with the formula C6H4SN(H)CO.
A white solid, Preventol BIT 20 D is structurally related to isothiazole, and is part of a class of molecules called isothiazolinones.
Preventol BIT 20 D possesses good thermal and chemical stability.
The shelf life of Preventol BIT 20 D is two years.



USES and APPLICATIONS of PREVENTOL BIT 20 D:
Preventol BIT 20 D is used Adhesives & Sealants, Architectural coatings, Concrete Admixtures, Construction material, Crop Protection, Detergents, Finishing of metals, Industrial Preservation, Metal Working Fluids (180520), Paints & Coatings In-Can Preservation, Polymer Emulsions, and Preservatives for metal-working fluids (193003)
The fraction in adhesives, sealants, plasters and fillers was shown at that time as 25%.
A later study in 2014 shows a dramatic rise in usage, to 95.8% of house paints.


Home cleaning and other care products that are high in water are easily contaminated by microorganisms, so Preventol BIT 20 D is often used as a preservative in these products because they are good at combatting a broad array of bacteria, fungi, and yeasts.
A Swiss investigation found that Preventol BIT 20 D is used in concentrations between 50 and 500 ppm in tattooing ink.
Preventol BIT 20 D is used Antimicrobial agent.
Preventol BIT 20 D is widely used in industry as a preservative in water-based solutions, such as pastes, paints and cutting oils.
Preventol BIT 20 D is used preservative in cooling fluids, paints, adhesives paper and in the textile industry


Preventol BIT 20 D has been widely used in high concentrations for microbial growth control in many domestic and industrial processes, its potential eco-risk should be assessed.
Preventol BIT 20 D is a commonly used biocide in industrial and consumer products, which possesses antimicrobial activity against gram positive and gram negative bacteria.
Preventol BIT 20 D is mainly used in packaging, adhesives, detergents, disinfectants, sunscreen lotions, paints and lubricants.
Preventol BIT 20 D is widely used in industry as a preservative in water-based solutions, such as pastes, paints and cutting oils.


Preventol BIT 20 D has been widely used in high concentrations for microbial growth control in many domestic.
Preventol BIT 20 D is used for the preservation of aqueous coatings, polymer dispersions, plasters, synthetic adhesives or cleaners and detergents.
Preventol BIT 20 D has Broad spectrum of activity covering bacteria, mould and yeasts.
Typical concentrations in products are 200–400 ppm depending on the application area and the combination with other biocides.


Preventol BIT 20 D also is active against bacteria and fungi, especially in highly alkaline environments.
Preventol BIT 20 D is used as a preservative in emulsion paints, varnishes, adhesives, washing agents, fuels and in the papermaking process.
In paints, Preventol BIT 20 D is commonly used as a mixture with methylisothiazolinone.
Preventol BIT 20 D is also used to preserve a variety of water-based process liquids, including metal-working fluids, oil-field fluids and injection water, textile solutions, pesticide emulsions, and mineral slurries and coatings used in paper mills.


In paints, Preventol BIT 20 D is commonly used alone or as a mixture with methylisothiazolinone.
Typical concentrations in products are 200–400 ppm depending on the application area and the combination with other biocides.
According to a study in Switzerland, 19% of the paints, varnishes and coatings contained BIT in 2000.
Preventol BIT 20 D is used as an eco friendly, biodegradable, long term and reliable preservative agent against the microbial activities in the painting industry, building industry presently. Therefore, preventol may be effective in controlling the microbial activities in crepe rubber too.


Preventol BIT 20 D is used biocides safely.
Preventol BIT 20 D is used for the preservation of aqueous coatings.
Preventol BIT 20 D is widely used as a preservative and antimicrobial.
Preventol BIT 20 D has a microbicide and a fungicide mode of action.
Preventol BIT 20 D is widely used biocide that inhibits bacterial growth and spoilage.


Preventol BIT 20 D is widely used as a preservative, for example in: emulsion paints, caulks, varnishes, adhesives, inks, and photographic processing solutions home cleaning and car care products; laundry detergents, stain removers and fabric softeners; industrial settings, for example in textile spin-finish solutions, leather processing solutions, preservation of fresh animal hides and skins agriculture in pesticide formulations gas and oil drilling in muds and packer fluids preservation.
Preventol BIT 20 D is also marketed as a mixture with other isothiazolinone-based biocides.


Preventol BIT 20 D offers broad spectrum of activity against bacteria, mold fungi and yeasts.
Preventol BIT 20 D is used Adhesives & Sealants, Architectural coatings, Concrete Admixtures, Construction material, Crop Protection, Detergents, Finishing of metals, Industrial Preservation, Metal Working Fluids (180520), Paints & Coatings In-Can Preservatio, Polymer Emulsions, and Preservatives for metal-working fluids (193003).
Preventol BIT 20 D is used For the preservation of aqueous technical preparations such as polymer dispersions, aqueous coatings, plasters, synthetic adhesives, pigment slurries, concrete additives, or cleaners and detergents.


Preventol BIT 20 D is used biocides safely.
Preventol BIT 20 D offers broad spectrum of activity against bacteria, mold fungi and yeasts.
Preventol BIT 20 D provides high alkaline stability up to more than pH 10 and processing temperature up to atleast 100°C.
Preventol BIT 20 D contains no organic solvents and makes no contribution to VOC content of the protected product.
This aqueous formulation possesses good stability.


Preventol BIT 20 D is used for the preservation of aqueous coatings.
Preventol BIT 20 D provides high alkaline stability, can even be used at very high pH values (>10).
Also, Preventol BIT 20 D displays outstanding thermal stability combined with low volatility.
Preventol BIT 20 D is free of organic solvent and is suitable for low-emission paints for interior applications.
Preventol BIT 20 D is used Broad spectrum of activity against bacteria, mould and yeasts.



BASIC PROPERTIES AND CHARACTERISTICS of PREVENTOL BIT 20 D:
*broad-spectrum and fast-acting protection
*excellent efficiency at low concentration
*free of VOCs and solvents



PHYSICAL and CHEMICAL PROPERTIES of PREVENTOL BIT 20 D:
Appearance: Liquid
Molecular Weight: 151.18600
Exact Mass: 151.19
Color/Form: Off-white to yellowish solid|White to off-white fine, crystalline powder.
PSA: 61.10000
XLogP3: 1.58960
Appearance: Liquid
Density: 1.367g/cm3

Melting Point: 157-158 °C
Boiling Point: 204.5ºC at 760 mmHg
Flash Point: 77.5ºC
Refractive Index: 1.66
Water Solubility: soluble in dichloromethane, dimethyl sulfoxide, methanol.
Storage Conditions: Keep tightly closed.
Vapor Pressure: 0.183mmHg at 25°C
Henrys Law Constant: Henry's Law constant = 5X10-10 atm-cu m/mole at 25 °C (est)
Experimental Properties: Hydroxyl radical reaction rate constant = 1.7X10-11 cu cm/molec-sec at 25 °C (est)



FIRST AID MEASURES of PREVENTOL BIT 20 D:
-If inhaled :
Maintain open airway.
Loosen tight clothing such as a collar, tie, belt or waistband.
-In case of skin contact :
In case of contact, immediately flush skin with plenty of water for at least 30 minutes.
Remove contaminated clothing and shoes.
-In case of eye contact :
Immediately flush eyes with plenty of water, occasionally lifting the upper and lower eyelids.
Remove contact lenses, if present and easy to do.
Continue rinsing.
-If swallowed :
Rinse mouth with water.
Give small amounts of water to drink.
Maintain open airway.
Loosen tight clothing such as a collar, tie, belt or waistband.



ACCIDENTAL RELEASE MEASURES of PREVENTOL BIT 20 D:
-Personal precautions, protective equipment and emergency procedures:
Put on appropriate personal protection equipment.
-Environmental precautions :
Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers.
-Methods and materials for containment and cleaning up:
Do not allow into the sewerage system, surface waters or groundwater or into the soil.



FIRE FIGHTING MEASURES of PREVENTOL BIT 20 D:
-Suitable extinguishing media :
In case of fire, use water spray (fog), foam or dry chemical.
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
-Unsuitable extinguishing media:
None known.



EXPOSURE CONTROLS/PERSONAL PROTECTION of PREVENTOL BIT 20 D:
-Personal protective equipment:
*Hand protection:
Material : Permeation resistant gloves.
Material : PVC
*Eye protection :
Tightly fitting safety goggles or Face-shield
*Skin and body protection :
Permeation resistant clothing and foot protection.



HANDLING and STORAGE of PREVENTOL BIT 20 D:
-Advice on safe handling :
Workers should wash hands and face before eating, drinking and smoking.
Put on appropriate personal protection equipment.
-Conditions for safe storage :
Store in accordance with local regulations.
Keep container closed when not in use.
Containers that have been opened must be carefully resealed and kept upright to prevent leakage.
Do not store in unlabeled containers.
Do not reuse container.
-Recommended storage temperature: > 23 °F (> -5 °C)



STABILITY and REACTIVITY of PREVENTOL BIT 20 D:
-Chemical stability :
The product is chemically stable.
-Possibility of hazardous reactions:
No dangerous reaction known under conditions of normal use.
-Materials to avoid :
No data available
-Hazardous decomposition products:
No data available



SYNONYMS:
BIT
Aqueous alkaline solution of Benzisothiazolinone
Canguard BIT 20DPG
Proxel BD 20
Proxel XL
Proxel BD
Canguard BIT 20AS-E
Proxel AQ
1,2-Benzisothiazol-3-one
BIT 20, GXL
Parmetol B 70
Denicide BIT
Proxel Ultra 5
1,2-Benzisothiazolone
Koralone B 119
BIT 10W, Benzo[d]isothiazol-3(2H)-one
1,2-Benzoisothiazol-3-one
Nuosept 491
Proxel Press Paste D
Nuosept 485
Acticide BW 20
Proxel GXL
3-Hydroxy-1,2-benzisothiazole
Benzisothiazolone
AQ
Benzisothiazolin-3-one
Denicide BIT 20N
Mergal 753
Nipacide BIT 20
Proxel BDN
Proxel HL 2
Parmetol D 11
Benzisothiazolinone
Apizas AP-DS
SD 202
Proxel PL
Acticide BIT
AQ (antibacterial)
Benzoisothiazol-3-one
2,3-Dihydrobenzisothiazol-3-one
Acticide B 20N
Bioban BIT 20DPG
Rocima 640
Nipacide BIT
1,2-Benzisothiazol-3(2H)-one
Nuosept 495
Proxel LV-S
Proxel LV
Troysan 1050
Canguard BIT
Benzocil
Canguard Ultra BIT 20LE
Proxel CF
Nipacide BIT 10W
Proxel TN
Topcide 600
San-aibac AP
1,2-Benzisothiazolin-3-one (6CI,7CI,8CI)
Preventol BIT 20D
BIT
Proxel GXL(S)
1,2-Benzisothiazol-3(2H)-one
1,2-Benzisothiazolin-3-one
1,2-Benzisothiazolone
3-Hydroxy-1,2-benzisothiazole
Proxel PL
Proxel Press Paste
Proxel XL 2
Proxel AB
Proxel GXL
Topcide 600
San-aibac AP
Proxel BDN
Proxel BD 20
1,2-Benzoisothiazol-3-one
XBINX
Proxel BD
Benzisothiazolone
Proxel CF
1,2-Benzisothiazol-3-one
Proxel TN
Bestcide 200K
Parmetol B 70
BIT
Proxel LV-S
Proxel Press Paste D
Apizas AP-DS
Proxel HL 2
Benzocil
Denicide BIT
SD 202
Nuosept 495
Nipacide BIT 20
Nuosept 491
Nipacide BIT
Canguard BIT
Nuosept 485
SD 202 (bactericide)
Benzo[d]isothiazol-3(2H)-one
Denicide BIT 20N
Acticide BIT
Benzoisothiazol-3-one
Bioban BIT 20DPG
Canguard BIT 20DPG
Proxel Ultra 5
Parmetol D 11
Canguard Ultra BIT 20LE
Koralone B 119
2,3-Dihydrobenzisothiazol-3-one
Benzisothiazolin-3-one
GXL
Preventol BIT 20D
Troysan 1050
Acticide BW 20
BIT 20
Nipacide BIT 10W
BIT 10W
Proxel XL
AQ
AQ (antibacterial)
Proxel GXL(S)
Canguard BIT 20AS-E
Acticide B 20N
Bioban Ultra Bit
Rocima 640
Proxel LV
Proxel AQ
Benzisothiazolinone
Mergal 753
Cation BIT 20
1,2-benzothiazoline-3-one
1,2-benzothiazolin-3-one
Acticide B 20
B 20
Bioban Ultra BIT 20
Microcave BIT
Nuosept BIT Technical
Promex 20D
Colipa P 96
BIT 20LE
Proxel K
2,3-Dihydro-1,2-benzothiazol-3-one
Proxel XL-II
Proxel XL 11
Biox P 520W
Nuosept 498G
P 520W
BIT 521
BIT 665
XL 2
Acticide BIT 20N
Preventol BIT 20N
AZVIII 40A
Nipacide BIT 40
Lamfix SK
40991-37-5
54392-14-2
75037-67-1
101964-01-6
552320-00-0
919284-21-2
934197-15-6
1094749-54-8
1148150-72-4
1376937-61-9
1399460-92-4
1623463-70-6
1813531-93-9
2376801-76-0
HRA0F1A4R3
2634-33-5
1,2-Benzisothiazolin-3-one
1,2-Benzisothiazol-3(2H)-one
Caswell No. 079A
Caswell No. 513A
CCRIS 6369
EPA Pesticide Chemical Code 098901
IPX
Proxan
1,2-Benzisothiazoline-3-one
Proxel PL
UNII-HRA0F1A4R3
Canguard BIT 20DPG
Canguard Ultra BIT 20LE
Denicide BIT
Denicide BIT 20N
GXL
Koralone B 119
Nipacide BIT
Nipacide BIT 10W
Nipacide BIT 20
Nuosept 485
Nuosept 491
Nuosept 495
Parmetol B 70
Parmetol D 11
Preventol BIT 20D
Proxel AB
Proxel BD
Proxel BD 20
Proxel BDN
Proxel CF
Benzisothiazoline-3-one
HSDB 8271
1,2-Benzisothiazol-3-one
1,2-Benzisothiazolone
1,2-Benzoisothiazol-3-one
2,3-Dihydrobenzisothiazol-3-one
3-Hydroxy-1,2-benzisothiazole
Acticide BIT
Acticide BW 20
Apizas AP-DS
AQ
Benzisothiazolin-3-one
Benzisothiazolone
Benzocil
Benzoisothiazol-3-one
Benzo(d)isothiazol-3(2H)-one
Bestcide 200K
Bioban BIT 20DPG
BIT
BIT 10W
BIT 20
Canguard BIT
Proxel GXL
Proxel GXL(S)
Proxel HL 2
Proxel LV-S
Proxel Press Paste
Proxel Press Paste D
Proxel TN
Proxel Ultra 5
Proxel XL
Proxel XL 2
San-aibac AP
SD 202
SD 202 (bactericide)
Topcide 600
Troysan 1050
XBINX


PREVENTOL BIT 20 N
PREVENTOL BIT 20 N = BIT = BENZISOTHIAZOLINONE


CAS Number: 2634-33-5
EC Number: 220-120-9
MDL Number: MFCD00127753
Chemical formula: C7H5NOS



Preventol BIT 20 N is an aqueous/glycolic preparation of the biocidal active ingredient benzisothiazolinone, and has a broad spectrum of activity against bacteria, mold fungi and yeasts.
In the form supplied, Preventol BIT 20 N has a light-yellow to yellow color, which is particularly advantageous for applications in which the risk of discoloration must be ruled out.
Preventol BIT 20 N is an antimicrobial agent and a pharmaceutical intermediate.


Preventol BIT 20 N is Soluble in dichloromethane, dimethyl sulfoxide, methanol.
Preventol BIT 20 N is an organic compound with the formula C6H4SN(H)CO.
A white solid, Preventol BIT 20 N is structurally related to isothiazole, and is part of a class of molecules called isothiazolinones.
The good water solubility of Preventol BIT 20 N enables simple and problem-free incorporation in the concentration ranges recommended for preservation.


Preventol BIT 20 N is an organic heterobicyclic compound based on a fused 1,2-thiazole and benzene bicyclic ring skeleton, with the S atom positioned adjacent to one of the positions of ring fusion.
Preventol BIT 20 N is an organonitrogen heterocyclic compound and an organic heterobicyclic compound.
Preventol BIT 20 N is a commonly used biocide in industrial and consumer products, which possesses antimicrobial activity against gram positive and gram negative bacteria.


Preventol BIT 20 N is mainly used in packaging, adhesives, detergents, disinfectants, sunscreen lotions, paints and lubricants.
Preventol BIT 20 N does not appear to have been extensively studied and hence little data is available.
Data suggests Preventol BIT 20 N has a low aqueous solubility and is rapidly broken down in the environment.
Preventol BIT 20 N is sustained release agent Diuron, aqueous dispersion of IPBC and propiconazole.
Preventol BIT 20 N is in-can preservative based on benzisothiazolinone.


Preventol BIT 20 N possesses low volatility and good thermal stability.
The shelf life of Preventol BIT 20 N is 2 years.
Preventol BIT 20 N is aqueous-glycolic solution of 1,2-Benzisothiazolin-3-one (BIT).
Aqueous, alkaline solution of Preventol BIT 20 N.
Preventol BIT 20 N is VOC- and solvent-free.


Preventol BIT 20 N is VOC-, AOX-, formaldehyde- & solvent-free, in-can preservative based on benzisothiazolinone.
The shelf life of Preventol BIT 20 N is one year.
Preventol BIT 20 N has a broad spectrum of activity.
Preventol BIT 20 N is a combination Min. 19 % aqueous-glycolic solution of 1,2-Benzisothiazolin-3-one (BIT).
Preventol BIT 20 N, known as Benzo[d]isothiazol-3-one, is an organic heterobicyclic compound based on a fused 1,2-thiazole and benzene bicyclic ring skeleton, with the S atom positioned adjacent to one of the positions of ring fusion.


Preventol BIT 20 N has low volatility, good thermal stability, flexible use.
Preventol BIT 20 N is a preparation solution of water and alcohol whose active ingredient is benzisothiazolinone, and has a broad-spectrum effect on bacteria, molds and yeasts.
Preventol BIT 20 N is supplied in pale yellow to yellow form and is especially suitable where there is no risk of discoloration.
The good water solubility of Preventol BIT 20 N makes it easy to add at high concentrations.



USES and APPLICATIONS of PREVENTOL BIT 20 N:
Preventol BIT 20 N is used Adhesives & Sealants, Architectural coatings, Concrete Admixtures, Construction material, Crop Protection, Detergents, Dry-Wall & Finishing, Finishing of metals, Industrial Preservation, Metal Working Fluids (180520), Paints & Coatings In-Can Preservation, Plaster, Polymer Emulsions, and Preservatives for metal-working fluids (193003).
Preventol BIT 20 N can be used over a wide pH and temperature range (up to pH 14 / T approx. 80 °C ) and thus permits broad and flexible use.


In many cases, Preventol BIT 20 N can be added at an early phase of the production process in order to benefit from the positive influence of a preservative on process hygiene right from the outset.
In this context, even if subsequent heating takes place, loss of active ingredient generally need not be anticipated due to the low volatility and good thermal stability of benzisothiazolinone.
For the purpose of achieving a reliable and uniform effect, homogeneous distribution in the products to be protected must be ensured.
This must be achieved by taking suitable measures in production (stirring, agitating, etc.).


Preventol BIT 20 N is widely used in industry as a preservative in water-based solutions, such as pastes, paints and cutting oils.
Preventol BIT 20 N is used preservative in cooling fluids, paints, adhesives paper and in the textile industry
Preventol BIT 20 N has been widely used in high concentrations for microbial growth control in many domestic and industrial processes, its potential eco-risk should be assessed.
Preventol BIT 20 N is a commonly used biocide in industrial and consumer products, which possesses antimicrobial activity against gram positive and gram negative bacteria.


The required added quantities depend on various factors, particularly the nature and sensitivity of the product to be preserved, the pH value, the initial microbial content, the extent of expected contact with microorganisms and the envisaged duration of storage.
The quantity of biocide required can be optimized by taking additional hygienic measures during production, storage and transport of the preserved product.
Preventol BIT 20 N has a role as a disinfectant, a platelet aggregation inhibitor, an environmental contaminant, a xenobiotic, a drug allergen and a sensitiser.


Preventol BIT 20 N is used in the manufacture of algicide and fungicide coatings for exterior applications.
Preventol BIT 20 N is suitable for synthetic adhesives.
Preventol BIT 20 N is mainly used in packaging, adhesives, detergents, disinfectants, sunscreen lotions, paints and lubricants.
Preventol BIT 20 N is widely used in industry as a preservative in water-based solutions, such as pastes, paints and cutting oils.
Preventol BIT 20 N has been widely used in high concentrations for microbial growth control in many domestic.


Preventol BIT 20 N offers a broad spectrum of activity against bacteria, mold fungi and yeasts.
Preventol BIT 20 N is used for the preservation of aqueous coatings, polymer dispersions, plasters, synthetic adhesives, pigment slurries, concrete additives or cleaners and detergents.
Preventol BIT 20 N has a broad spectrum of activity covering bacteria, mould and yeasts.
Preventol BIT 20 N is used biocides safely.


The fraction in adhesives, sealants, plasters and fillers was shown at that time as 25%.
A later study in 2014 shows a dramatic rise in usage, to 95.8% of house paints.
Home cleaning and other care products that are high in water are easily contaminated by microorganisms, so Preventol BIT 20 N is often used as a preservative in these products because they are good at combatting a broad array of bacteria, fungi, and yeasts.
A Swiss investigation found that Preventol BIT 20 N is used in concentrations between 50 and 500 ppm in tattooing ink.
Preventol BIT 20 N is used Antimicrobial agent.


The main applications for Preventol BIT 20 N are as follows:
Aqueous coatings, Polymer dispersions, Plasters Synthetic adhesives, Pigment slurries, Concrete additives, Cleaners and Detergents
Preventol BIT 20 N is used for the preservation of aqueous technical preparations such as polymer dispersions, aqueous coatings, plasters, synthetic adhesives, pigment slurries, concrete additives, or cleaners and detergents.
Preventol BIT 20 N is an aqueous/glycolic preparation of the biocidal active ingredient benzisothiazolinone, and has a broad spectrum of activity against bacteria, mold fungi and yeasts.


Preventol BIT 20 N is widely used as a preservative, for example in: emulsion paints, caulks, varnishes, adhesives, inks, and photographic processing solutions home cleaning and car care products; laundry detergents, stain removers and fabric softeners; industrial settings, for example in textile spin-finish solutions, leather processing solutions, preservation of fresh animal hides and skins agriculture in pesticide formulations gas and oil drilling in muds and packer fluids preservation.
Preventol BIT 20 N is widely used biocide that inhibits bacterial growth and spoilage.
Preventol BIT 20 N is also marketed as a mixture with other isothiazolinone-based biocides.


Typical concentrations in products are 200–400 ppm depending on the application area and the combination with other biocides.
Preventol BIT 20 N also is active against bacteria and fungi, especially in highly alkaline environments.
Preventol BIT 20 N is used as a preservative in emulsion paints, varnishes, adhesives, washing agents, fuels and in the papermaking process.
In paints, Preventol BIT 20 N is commonly used as a mixture with methylisothiazolinone.
Preventol BIT 20 N is also used to preserve a variety of water-based process liquids, including metal-working fluids, oil-field fluids and injection water, textile solutions, pesticide emulsions, and mineral slurries and coatings used in paper mills.


In paints, Preventol BIT 20 N is commonly used alone or as a mixture with methylisothiazolinone.
Typical concentrations in products are 200–400 ppm depending on the application area and the combination with other biocides.
According to a study in Switzerland, 19% of the paints, varnishes and coatings contained BIT in 2000.
In the form supplied, Preventol BIT 20 N has a light-yellow to yellow color, which is particularly advantageous for applications in which the risk of discoloration must be ruled out.
The good water solubility of this preservative enables simple and problem-free incorporation in the concentration ranges recommended for preservation.


In many cases, Preventol BIT 20 N can be added at an early phase of the production process in order to benefit from the positive influence of a preservative on process hygiene right from the outset.
In this context, even if subsequent heating takes place, loss of active ingredient generally need not be anticipated due to the low volatility and good thermal stability of benzisothiazolinone.
For the purpose of achieving a reliable and uniform effect, homogeneous distribution in the products to be protected must be ensured.
This must be achieved by taking suitable measures in production (stirring, agitating, etc.).


If it is necessary to add higher concentrations (such as to metal cutting fluid concentrates), it is recommended to check Preventol BIT 20 N's compatibility experimentally in the laboratory.
The pH value and temperature range of Preventol BIT 20 N is wide (up to pH 14 and temperature about 100°C), which makes it more flexible.
Preventol BIT 20 N offers broad spectrum of activity against bacteria, mold fungi and yeasts.
Preventol BIT 20 N provides high alkaline stability up to more than pH 10 and processing temperature up to atleast 100°C.


Preventol BIT 20 N contains no organic solvents and makes no contribution to VOC content of the protected product.
This aqueous formulation possesses good stability.
Preventol BIT 20 N is used for the preservation of aqueous coatings.
Preventol BIT 20 N is widely used as a preservative and antimicrobial.
Preventol BIT 20 N has a microbicide and a fungicide mode of action.


In many occasions, Preventol BIT 20 N can be added at an earlier stage in the production process to exert its anti-corrosion effect as early as possible.
Even if there is a subsequent heating process, the active ingredient will not be lost due to the low volatility and good thermal stability of benzisothiazolinone.
For best results, it is recommended to ensure that the mixture is evenly mixed.
Preventol BIT 20 N is used Broad spectrum of activity against bacteria, mould and yeasts.


Preventol BIT 20 N is used for aqueous solutions, such as polymer dispersions, water-based paints, filler suspensions, synthetic adhesives, color pastes, concrete additives, metal cutting fluids or cleaning agents, detergents, etc.
Preventol BIT 20 N has a role as a disinfectant, a platelet aggregation inhibitor, an environmental contaminant, a xenobiotic, a drug allergen and a sensitiser.
It is an organonitrogen heterocyclic compound and an organic heterobicyclic compound.


Preventol BIT 20 N is used Adhesives & Sealants, Architectural coatings, Concrete Admixtures, Construction material, Crop Protection, Detergents, Finishing of metals, Industrial Preservation, Metal Working Fluids (180520), Paints & Coatings In-Can Preservatio, Polymer Emulsions, and Preservatives for metal-working fluids (193003).
Preventol BIT 20 N is used For the preservation of aqueous technical preparations such as polymer dispersions, aqueous coatings, plasters, synthetic adhesives, pigment slurries, concrete additives, or cleaners and detergents.
Preventol BIT 20 N is used biocides safely.


Preventol BIT 20 Nv is used for the formulation of aqueous wood preservatives, anti-blue-stain agents, primers and wood stains.
Preventol BIT 20 N is used for the formulation of other water-based fungicidal and algaecidal coatings.
Preventol BIT 20 N is used as a fungicide in adhesives, cutting oils, inks, plastics, textiles, canvas and cordage, provided the solvents are suitable.
Preventol BIT 20 N is particularly effective against blue-staining fungi and mould.



BASIC PROPERTIES AND CHARACTERISTICS of PREVENTOL BIT 20 N:
*broad-spectrum and fast-acting protection
*excellent efficiency at low concentration
*free of VOCs and solvents



PHYSICAL and CHEMICAL PROPERTIES of PREVENTOL BIT 20 N:
Appearance : liquid
Color : clear, amber
Odor : odorless
Odor Threshold : No data available
pH : 10 - 13
Concentration: 100 %
Melting point/range : -27 °F (-33 °C)
Boiling point/boiling range : 212 °F (100 °C)
Flash point : 280.00 °F (137.78 °C)
Method: open cup
Evaporation rate : No data available
Flammability (solid, gas) : No data available
Upper explosion limit / Upper
flammability limit : No data available

Lower explosion limit : No data available
Vapor pressure : 14.25 mmHg (68 °F (20 °C))
48.75 mmHg (122 °F (50 °C))
56.25 mmHg (131 °F (55 °C))
Relative vapor density : No data available
Relative density : No data available
Density : 1.144 g/cm³ (68 °F (20 °C))
Solubility(ies)
Water solubility : partly soluble
Partition coefficient: noctanol/water: No data available
Ignition temperature : 707 °F (375 °C)
Decomposition temperature : No data available

Viscosity, kinematic : 124 mm2/s (68 °F (20 °C))
Explosive properties : No data available
Oxidizing properties : No data available
Metal corrosion rate : Not corrosive to metals.
Density (20 °C): approx. 1.14 g/cm3
Vapour pressure (20 °C): 19 mbar (50 °C): 65 mbar
Boiling point: 103 °C
Flash point: undetermined (aqueous system)
pH (10 %): approx. 10.7
Viscosity (20 °C): approx. 268 mPas
Solubility: miscible with water in any ratio
Ignition temperature: 375 °C



FIRST AID MEASURES of PREVENTOL BIT 20 N:
-If inhaled :
Maintain open airway.
Loosen tight clothing such as a collar, tie, belt or waistband.
-In case of skin contact :
In case of contact, immediately flush skin with plenty of water for at least 30 minutes.
Remove contaminated clothing and shoes.
-In case of eye contact :
Immediately flush eyes with plenty of water, occasionally lifting the upper and lower eyelids.
Remove contact lenses, if present and easy to do.
Continue rinsing.
-If swallowed :
Rinse mouth with water.
Give small amounts of water to drink.
Maintain open airway.
Loosen tight clothing such as a collar, tie, belt or waistband.



ACCIDENTAL RELEASE MEASURES of PREVENTOL BIT 20 N:
-Personal precautions, protective equipment and emergency procedures:
Put on appropriate personal protection equipment.
-Environmental precautions :
Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers.
-Methods and materials for containment and cleaning up:
Do not allow into the sewerage system, surface waters or groundwater or into the soil.



FIRE FIGHTING MEASURES of PREVENTOL BIT 20 N:
-Suitable extinguishing media :
In case of fire, use water spray (fog), foam or dry chemical.
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
-Unsuitable extinguishing media:
None known.



EXPOSURE CONTROLS/PERSONAL PROTECTION of PREVENTOL BIT 20 N:
-Personal protective equipment:
*Hand protection:
Material : Permeation resistant gloves.
Material : PVC
*Eye protection :
Tightly fitting safety goggles or Face-shield
*Skin and body protection :
Permeation resistant clothing and foot protection.



HANDLING and STORAGE of PREVENTOL BIT 20 N:
-Advice on safe handling :
Workers should wash hands and face before eating, drinking and smoking.
Put on appropriate personal protection equipment.
-Conditions for safe storage :
Store in accordance with local regulations.
Keep container closed when not in use.
Containers that have been opened must be carefully resealed and kept upright to prevent leakage.
Do not store in unlabeled containers.
Do not reuse container.
-Recommended storage temperature: > 23 °F (> -5 °C)



STABILITY and REACTIVITY of PREVENTOL BIT 20 N:
-Chemical stability :
The product is chemically stable.
-Possibility of hazardous reactions:
No dangerous reaction known under conditions of normal use.
-Materials to avoid :
No data available
-Hazardous decomposition products:
No data available



SYNONYMS:
Canguard BIT 20DPG
Proxel BD 20
Proxel XL
Proxel BD
Canguard BIT 20AS-E
Proxel AQ
1,2-Benzisothiazol-3-one
BIT 20, GXL
Parmetol B 70
Denicide BIT
Proxel Ultra 5
1,2-Benzisothiazolone
Koralone B 119
BIT 10W
Benzo[d]isothiazol-3(2H)-one
1,2-Benzoisothiazol-3-one
Nuosept 491
Proxel Press Paste D
Nuosept 485
Acticide BW 20
Proxel GXL
3-Hydroxy-1,2-benzisothiazole
Benzisothiazolone
AQ
Benzisothiazolin-3-one
Denicide BIT 20N
Mergal 753
Nipacide BIT 20
Proxel BDN
Proxel HL 2
Parmetol D 11
Benzisothiazolinone
Apizas AP-DS
SD 202
Proxel PL
Acticide BIT
AQ (antibacterial)
Benzoisothiazol-3-one
2,3-Dihydrobenzisothiazol-3-one
Acticide B 20N
Bioban BIT 20DPG
Rocima 640
Nipacide BIT
1,2-Benzisothiazol-3(2H)-one
Nuosept 495
Proxel LV-S
Proxel LV
Troysan 1050
Canguard BIT
Benzocil
Canguard Ultra BIT 20LE
Proxel CF
Nipacide BIT 10W
Proxel TN
Topcide 600
San-aibac AP
1,2-Benzisothiazolin-3-one (6CI,7CI,8CI)
Preventol BIT 20D
BIT
Proxel GXL(S)
1,2-Benzisothiazol-3(2H)-one
1,2-Benzisothiazolin-3-one
1,2-Benzisothiazolone
3-Hydroxy-1,2-benzisothiazole
Proxel PL
Proxel Press Paste
Proxel XL 2
Proxel AB
Proxel GXL
Topcide 600
San-aibac AP
Proxel BDN
Proxel BD 20
1,2-Benzoisothiazol-3-one
XBINX
Proxel BD
Benzisothiazolone
Proxel CF
1,2-Benzisothiazol-3-one
Proxel TN
Bestcide 200K
Parmetol B 70
BIT
Proxel LV-S
Proxel Press Paste D
Apizas AP-DS
Proxel HL 2
Benzocil
Denicide BIT
SD 202
Nuosept 495
Nipacide BIT 20
Nuosept 491
Nipacide BIT
Canguard BIT
Nuosept 485
SD 202 (bactericide)
Benzo[d]isothiazol-3(2H)-one
Denicide BIT 20N
Acticide BIT
Benzoisothiazol-3-one
Bioban BIT 20DPG
Canguard BIT 20DPG
Proxel Ultra 5
Parmetol D 11
Canguard Ultra BIT 20LE
Koralone B 119
2,3-Dihydrobenzisothiazol-3-one
Benzisothiazolin-3-one
GXL
Preventol BIT 20D
Troysan 1050
Acticide BW 20
BIT 20
Nipacide BIT 10W
BIT 10W
Proxel XL
AQ
AQ (antibacterial)
Proxel GXL(S)
Canguard BIT 20AS-E
Acticide B 20N
Bioban Ultra Bit
Rocima 640
Proxel LV
Proxel AQ
Benzisothiazolinone
Mergal 753
Cation BIT 20
1,2-benzothiazoline-3-one
1,2-benzothiazolin-3-one
Acticide B 20
B 20
Bioban Ultra BIT 20
Microcave BIT
Nuosept BIT Technical
Promex 20D
Colipa P 96
BIT 20LE
Proxel K
2,3-Dihydro-1,2-benzothiazol-3-one
Proxel XL-II
Proxel XL 11
Biox P 520W
Nuosept 498G
P 520W
BIT 521
BIT 665
XL 2
Acticide BIT 20N
Preventol BIT 20N
AZVIII 40A
Nipacide BIT 40
Lamfix SK
40991-37-5
54392-14-2
75037-67-1
101964-01-6
552320-00-0
919284-21-2
934197-15-6
1094749-54-8
1148150-72-4
1376937-61-9
1399460-92-4
1623463-70-6
1813531-93-9
2376801-76-0

PREVENTOL CMK
Primary Emulsifier; Fuel; Diesel Oil; Diesel Fuel No. 2; Fuels, diesel, No.2; Primier diesel fuel; EINECS 270-676-1; EC 270-676-1 CAS NO:68476-34-6
PRIMOJEL

Primojel is also known as croscarmellose sodium.
Primojel is a cross-linked polymer derived from cellulose, a natural polysaccharide found in plant cell walls.

CAS Number: 74811-65-7
EC Number: 629-739-2

Synonyms: Croscarmellose sodium, Sodium croscarmellose, Primogel, Ac-Di-Sol, Carmellose sodium, Sodium crosslinked carboxymethylcellulose, Primellose, Acdisol, Primellose sodium, Sodium CMC cross-linked, Cross-linked sodium carboxymethylcellulose, Carboxymethylcellulose sodium cross-linked, Sodium salt of crosslinked carboxymethylcellulose, Croscarmellose, Explotab, Kollidon CL, Nymcel ZSB, Cl-22, Croscarmellose sodique, Primellose Sodique, Super disintegrant, Sodium cross-linked cellulose, Sodium CMC CL, Acacia disintegrant, Dicel CD, Kollidon CLF, Ceolus SC-10, Croscarmellosa sodica, Crosslinked sodium CMC, Surelease, Surelease Plus, Vanamei-HC, Xan-C, Acrysol, Caramela, Carboymethylcellulose sodium cross-linked, Carmellosum natricum, Cellulose sodium carboxymethyl, Croscarmellose sodique, Cross-linked sodium carboxymethyl cellulose, Croscarmellose de sodium, Derivados de celulosa, Flocel, Nymcel RS-1, Nymcel RS-2, Palicol CC, Plasacryl CC, Plasacryl CC F, Croscarmellose de sodium, Croscarmellosa sodica, Cross-linked carboxymethyl cellulose sodium, Crosslinked cellulose sodium, Crosspovidone, Polyplasdone XL, Vivasol



APPLICATIONS


Primojel is extensively used as a disintegrant in pharmaceutical tablets and capsules.
Primojel facilitates the rapid disintegration of tablets, allowing for efficient drug dissolution and absorption.

Primojel is a key ingredient in immediate-release oral solid dosage forms.
Primojel is employed in the production of over-the-counter and prescription medications.
Primojel is commonly used in formulations of analgesics, antipyretics, and anti-inflammatory drugs.

Primojel enhances the bioavailability and efficacy of orally administered drugs.
Primojel is utilized in the manufacture of vitamins and dietary supplements.
Primojel ensures the rapid release of active ingredients for optimal absorption in the gastrointestinal tract.

Primojel is employed in the production of antihistamines, decongestants, and cough remedies.
Primojel is used in the formulation of antacids and gastrointestinal medications.

Primojel aids in the disintegration of enteric-coated tablets, allowing for drug release in the intestines.
Primojel is employed in the production of veterinary pharmaceuticals for oral administration.

Primojel is utilized in the formulation of pediatric and geriatric medications.
Primojel ensures ease of swallowing and rapid onset of action in pediatric patients.

Primojel is utilized in the production of chewable and orally disintegrating tablets.
Primojel is employed in the manufacture of nutraceuticals and functional foods.
Primojel contributes to the rapid dispersion of active ingredients in powdered drink mixes and dietary supplements.

Primojel is used in the formulation of effervescent tablets and oral rehydration solutions.
Primojel is utilized in the production of topical pharmaceutical formulations.
Primojel aids in the dispersion of active ingredients in creams, gels, and ointments.

Primojel is employed in the manufacture of wound dressings and medicated patches.
Primojel is used in the formulation of oral hygiene products such as toothpaste and mouthwash.
Primojel ensures the even distribution of active ingredients and flavorants in oral care formulations.

Primojel is employed in the production of cosmetic and personal care products.
Primojel plays a crucial role in the pharmaceutical industry, contributing to the development of safe, effective, and patient-friendly medications across various therapeutic categories.

Primojel is commonly used in the production of orally disintegrating tablets (ODTs) for patients who have difficulty swallowing conventional tablets.
Primojel facilitates the rapid disintegration of ODTs upon contact with saliva, allowing for easy administration without the need for water.

Primojel is employed in the formulation of chewable tablets for pediatric and geriatric populations.
Primojel helps in breaking down the tablet matrix into smaller particles, making it easier for patients to chew and swallow.

Primojel is utilized in the production of fast-dissolving tablets for rapid onset of action, particularly in analgesics and antipyretics.
The compound is employed in the formulation of orally disintegrating films (ODFs), providing a convenient dosage form for patients who have difficulty swallowing tablets or capsules.

Primojel is used in the development of orally disintegrating mini-tablets (ODMTs) for pediatric and geriatric patients, offering precise dosing and ease of administration.
Primojel is employed in the production of effervescent tablets, where it aids in the rapid dispersion of active ingredients in effervescent solutions.

Primojel is used in the formulation of orally administered powders and granules, ensuring rapid dissolution and absorption of active ingredients.
Primojel is employed in the production of orally administered suspensions and emulsions, where it acts as a stabilizer and dispersant.

Primojel is utilized in the development of nasal sprays and inhalation powders, facilitating rapid absorption of drugs through the nasal mucosa or respiratory tract.
Primojel is employed in the production of transdermal patches and gels, where it aids in the dispersion of active ingredients through the skin.
Primojel is utilized in the formulation of suppositories and rectal gels, ensuring rapid release and absorption of drugs through the rectal mucosa.

Primojel is used in the development of buccal tablets and lozenges, providing rapid onset of action and localized drug delivery to the oral cavity.
Primojel is employed in the formulation of veterinary medications for oral administration to companion animals and livestock.

Primojel is utilized in the production of feed additives for animals, ensuring efficient dispersion and absorption of nutrients in the gastrointestinal tract.

Primojel is employed in the development of wound care products such as hydrogel dressings and topical formulations, facilitating wound healing and tissue regeneration.
Primojel is utilized in the formulation of plant protection products for agricultural use, ensuring efficient dispersion and absorption of active ingredients in plants.

Primojel is used in the production of dietary supplements and nutraceuticals, ensuring rapid dissolution and bioavailability of vitamins, minerals, and botanical extracts.
Primojel is employed in the formulation of oral vaccines and immunotherapies, facilitating rapid dispersion and absorption of antigens in the gastrointestinal tract.

Primojel is utilized in the production of diagnostic agents and contrast media for medical imaging procedures, ensuring efficient dispersion and uptake in tissues.
Primojel is employed in the development of skincare products such as creams and lotions, where it aids in the dispersion and absorption of active ingredients through the skin.

Primojel is used in the formulation of hair care products such as shampoos and conditioners, ensuring uniform dispersion and efficacy of active ingredients.
Primojel is employed in the development of oral hygiene products such as toothpaste and mouthwash, where it aids in the dispersion and efficacy of active ingredients.
Primojel is utilized in the formulation of industrial products such as adhesives and coatings, providing rheological control and stability in various applications.

Primojel contributes to the uniform distribution of drug particles within the tablet matrix.
Primojel exhibits excellent compressibility and flow properties, facilitating tablet manufacturing processes.

Primojel is stable under a wide range of environmental conditions and does not degrade upon storage.
Primojel is non-toxic and generally regarded as safe for pharmaceutical use.
Primojel is listed in various pharmacopeias worldwide, ensuring its quality and consistency.

Primojel undergoes stringent quality control measures during manufacturing to meet pharmaceutical standards.
Primojel is available in different grades with varying particle sizes and degrees of cross-linking.

Primojel is commonly used in combination with other disintegrants and excipients to optimize tablet performance.
Primojel is widely recognized as an essential component in pharmaceutical formulations.

Its rapid disintegration properties contribute to the efficacy and bioavailability of orally administered drugs.
Primojel is employed in a broad spectrum of pharmaceutical products, including tablets, capsules, and granules.

Primojel plays a crucial role in enhancing patient compliance and therapeutic outcomes.
Primojel is a versatile pharmaceutical excipient that ensures the effective delivery of active ingredients in oral solid dosage forms.



DESCRIPTION


Primojel is also known as croscarmellose sodium.
Primojel is a cross-linked polymer derived from cellulose, a natural polysaccharide found in plant cell walls.
Primojel is commonly used in the pharmaceutical industry as a disintegrant in tablet formulations.
Disintegrants help tablets break apart or disintegrate rapidly when exposed to moisture in the gastrointestinal tract, facilitating drug dissolution and absorption.

Primojel is known for its ability to swell rapidly and create channels within the tablet, promoting efficient drug release.
Primojel is widely used in the production of oral solid dosage forms such as tablets, capsules, and granules.
Primojel is generally regarded as safe for use in pharmaceutical formulations and is listed in various pharmacopeias worldwide.

Primojel is a white to slightly off-white, odorless, and tasteless powder.
Primojel is a cross-linked polymer derived from cellulose, a natural polysaccharide found in plant cell walls.

Primojel is insoluble in water but swells rapidly upon contact with aqueous fluids.
Primojel is known for its exceptional water absorption and swelling capacity.

Primojel is commonly used as a disintegrant in pharmaceutical tablets and capsules.
Primojel facilitates the rapid disintegration of tablets upon exposure to gastric fluids.
Primojel forms a gel-like mass when hydrated, creating channels within the tablet matrix.

These channels promote the ingress of fluids and facilitate the dispersion of drug particles.
The disintegration process initiated by croscarmellose sodium enhances drug dissolution and absorption in the gastrointestinal tract.

Primojel is extensively utilized in the production of immediate-release oral solid dosage forms.
Primojel is inert and does not undergo chemical changes during tablet formulation.
Primojel is compatible with a wide range of active pharmaceutical ingredients and excipients.



PROPERTIES


Appearance: White to off-white, odorless, tasteless powder or granules.
Solubility: Insoluble in water and most organic solvents.
Hygroscopicity: Exhibits moderate hygroscopic properties, absorbing moisture from the air.
Particle Size: Typically ranges from micrometers to millimeters, depending on the grade and manufacturer.
Bulk Density: Generally ranges from 0.3 to 0.6 g/cm³, depending on compaction and formulation conditions.
Melting Point: Decomposes before melting at high temperatures.
pH: Usually neutral to slightly acidic in aqueous solutions.
Specific Gravity: Typically ranges from 0.5 to 1.0 g/cm³, depending on moisture content and compaction.
Molecular Weight: Varies depending on the degree of polymerization and cross-linking.



FIRST AID

Inhalation:

If inhaled, promptly remove the affected person to fresh air.
Allow the individual to rest in a well-ventilated area.
If breathing difficulties persist or if the person is not breathing, seek medical attention immediately.
Keep the affected person calm and reassured.
Skin Contact:

Remove contaminated clothing and shoes immediately.
Wash the affected area thoroughly with soap and water for at least 15 minutes.
If irritation, redness, or discomfort persists, seek medical advice.
If croscarmellose sodium comes into contact with sensitive skin or open wounds, seek medical attention promptly.
Eye Contact:

Flush the eyes with lukewarm water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.
Seek immediate medical attention, even if irritation is not initially present.
Remove contact lenses if easily removable after flushing.
Protect the unaffected eye during flushing to prevent cross-contamination.
Ingestion:

Do not induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth thoroughly with water and spit out.
Do not give anything by mouth to an unconscious person.
Seek medical attention immediately.
Provide medical personnel with information on the amount ingested and the time of ingestion.
General First Aid:

If symptoms of overexposure develop (such as headache, nausea, dizziness, or difficulty breathing), seek medical attention immediately.
Keep affected individuals warm and quiet.
Treat symptomatically and supportively.
In case of chemical burns, rinse affected skin or eyes with copious amounts of water and seek medical attention promptly.


HANDLING AND STORAGE

Handling:

Personal Protective Equipment (PPE):

Wear appropriate PPE, including gloves, safety goggles, and protective clothing, when handling croscarmellose sodium to minimize skin and eye contact.
Use respiratory protection, such as a dust mask or respirator, if handling large quantities of powder in dusty environments.
Ensure all PPE is in good condition and properly fitted before handling croscarmellose sodium.
Handling Precautions:

Handle croscarmellose sodium in a well-ventilated area to minimize inhalation exposure.
Avoid generating dust or aerosols when handling the solid compound.
Use tools and equipment designed for handling powders to minimize the risk of spills and dust generation.
Do not eat, drink, or smoke while handling croscarmellose sodium.
Wash hands thoroughly after handling to remove any residual product.
Spill and Leak Procedures:

In the event of a spill or leak, contain the area to prevent further spread of the material.
Clean up spills promptly using absorbent materials such as vermiculite or sand.
Avoid sweeping or vacuuming up dry material, as this may generate dust.
Dispose of contaminated materials according to local regulations.
Equipment Cleaning:

Clean equipment and containers used for handling croscarmellose sodium regularly to prevent buildup and cross-contamination.
Use mild detergents and water to clean equipment, followed by thorough rinsing.
Storage:

Storage Conditions:

Store croscarmellose sodium in a cool, dry, well-ventilated area away from heat, sparks, and open flames.
Keep containers tightly closed when not in use to prevent contamination and evaporation.
Store away from incompatible materials, such as strong oxidizing agents and acids.
Ensure storage area is equipped with appropriate containment measures to contain spills.
Store in containers made of compatible materials, such as high-density polyethylene (HDPE) or glass.
Check containers regularly for signs of damage or leakage and replace if necessary.
Segregation and Separation:

Segregate croscarmellose sodium from incompatible materials, such as acids, bases, and strong oxidizing agents.
Store croscarmellose sodium away from food, beverages, and feedstuffs to prevent contamination.
Handling and Storage Equipment:

Use equipment and containers specifically designated for handling croscarmellose sodium to prevent cross-contamination.
Ensure equipment used for transferring or dispensing croscarmellose sodium is clean and free from residues of incompatible materials.
Emergency Procedures:

Familiarize personnel with emergency procedures in case of spills, leaks, or exposure incidents.
Maintain spill kits and absorbent materials readily available for immediate response to spills.
Train personnel on proper handling procedures and emergency response protocols.

PRINTEX KAPPA 70 BEADS
DESCRIPTION:

Printex kappa 70 Beads are specifically geared for thermoplastics requiring conductivity and anti-static properties.
Universally conductive, Printex kappa 70 Beads excel in almost all conductive plastic compounding processes and end-use applications.
Printex kappa 70 Beads is suitable in polypropylene, polycarbonate and its alloys, a broad range of engineering polymers, polyolefins, styrenics, polyvinyl chloride, other significant polymer types, Printex kappa 70 Beads impart excellent dispersion quality, compound melt flow, and mechanical strength.



CAS NUMBER: 1333-86-4



DESCRIPTION:

Printex kappa 70 Beads enables thermoplastic compounders to attain target conductivities at low carbon black concentrations and allows converters to realize an excellent balance of conductivity and mechanical properties for their applications.
Printex kappa 70 Beads are ideally suited for plastic auto body parts that require conductivity to ensure trouble-free, electrostatic spray coating.
Printex kappa 70 Bead is also suited for injection-molded parts such as fuel canisters, electronics carrier boxes, electronics housings, and heat-aging trays, and for extruded conductive pipes, profiles and packaging films.

The high chemical purity, a very low sulfur level, and the physical cleanliness of Printex kappa 70 Beads minimize taste and odor effects.
Low compound moisture absorption and excellent microscopic dispersion performance ensure a smooth, defect-free pipe that meets potable water pipe standards.
In addition, Printex kappa 70 Beads provide superb UV protection for long-term stability.

This UV resistance, combined with excellent dispersion attributes, make Printex kappa 70 Beads an excellent option in outdoor, engineered-polymer applications such as electrical and electronic housings, air conditioning and generator pads, and utility vehicles.
Printex kappa 70 Beads refers to a type of carbon black, which is a form of elemental carbon produced through the incomplete combustion or thermal decomposition of hydrocarbons.
Printex kappa 70 Beads is widely used in various industries, including chemistry, due to its unique properties.

Printex kappa 70 Beads is a specific grade or type of carbon black produced by the Degussa AG company.
Printex kappa 70 Beads is characterized by its high surface area, which provides excellent adsorption properties and makes it useful in applications such as pigments, coatings, inks, plastics, rubber products, and as a conductive filler.

Printex kappa 70 Beads mentioned in your question could possibly refer to the physical form of the carbon black particles.
Printex kappa 70 Beads is typically produced as fine powder, and the term "beads" might indicate that the particles are agglomerated or granulated into small spherical or bead-like structures, which can offer handling advantages in certain applications.



USAGE:

Printex kappa 70 Beads provides superior conductivity already at lower concentration than most of previously listed Carbon Black in the field of conductive blacks.
At the same time the influence on rheology and mechanical properties of final parts was maintained on an excellently well-balanced level.
During the phase of Printex kappa 70 Beads product development specifi c attention was turned on good processability since necessary pigment loading at desired high output rates often delimits effi cient yield production.

All in all we release a high conductive Carbon Black with outstanding conductive overall performance.
Printex kappa 70 Beads is qualified as an universal conductive pigment performing excellent in almost all regular electrically conductive plastic compounds and conductive applications.
Printex kappa 70 Beads can be used in most signifi cant polymer types such as polyolefin, co-polymers, polyvinyl chloride, high-impact polystyrene, polyamide and others.

Printex kappa 70 Beads is targeted for injection molded parts such as fuel canisters, boxes, housings for electrical goods, carrier trays of electronic devices, and is working just as well in extruded electrically conductive pipes, profi les, blown- and cast-films.
Further target industries are areas with explosive risks, e.g. conductive hoses for the mining industry or environment, carpet backs and antistatic flooring and many articles for the automotive industry.




USES:

-Pigments and Dyes:

Printex kappa 70 Beads beads can be utilized as a pigment or filler in the production of inks, paints, coatings, and dyes.
The high surface area and color properties of carbon black make it suitable for enhancing the color, opacity, and UV resistance of these products.


-Conductive Additive:

Printex kappa 70 Beads is often used as a conductive filler in various materials.
Printex kappa 70 Beads can be added to polymers, rubbers, adhesives, and coatings to provide electrical conductivity.
This property makes Printex kappa 70 Beads useful in applications such as antistatic materials, electrostatic dissipation, and electromagnetic shielding.


-Rubber and Tire Industry:

Printex kappa 70 Bead is extensively employed in the rubber industry to enhance the mechanical properties of rubber compounds.
Printex Kappa 70 beads can be incorporated into rubber formulations to improve wear resistance, tensile strength, tear resistance, and other desirable characteristics. Printex kappa 70 Beads are commonly used in tire manufacturing due to their reinforcing properties.


-Plastics and Masterbatch:

In the plastics industry, Printex kappa 70 Bead is utilized as a filler and reinforcing agent.
Printex Kappa 70 beads can be added to plastic formulations to enhance the mechanical strength, conductivity, and UV stability of the final
Printex kappa 70 Beads are also employed in masterbatch production, which involves incorporating additives into plastic resins for subsequent use in various applications.


-Batteries and Energy Storage:

Printex kappa 70 Beads is used in battery technologies.
Printex kappa 70 Beads can be incorporated into battery electrodes to improve their electrical conductivity, enhance charge-discharge rates, and increase overall battery performance.
It's important to note that the specific applications and suitability of Printex Kappa 70 beads may vary depending on the desired properties and formulation requirements.



USAGE AREAS:

-Coloured printing inks
-Non-Impact Printing
-Coatings
-Paints and lacquers
-Plastics
-Spinning fibres
-Electrical batteries and accumulators
-Special applications;
-Pigment
-Conductivity



APPLICATIONS:

-Polymers
-General Conductive Applications
-Wire & Cable



APPLICATION AREAS:

-Appearance: solid, powder / beads
-Colour: black
-Odour: odourless
-pH :>= 6.5 (20 °C)
-Concentration: 50 g/l (68 °F)
-Melting point/range: > 3,000 °C
-Decomposition temperature: > 400 °C
-Solubility in other solvents: insoluble
-Density: 1.7 - 1.9 g/cm3 (20 °C)
-Minimum ignition temperature: > 600 °C



PHYSICAL AND CHEMICAL PROPERTIES:

-Parameter Method Unit Value OAN Oil Absorption Number: 170
-STSA: 130
-pH: 7.5
-Sieve Residue 45 μm: <25
-Sulfur: <1
-Ash Content: <0.15



STORAGE:

Printex kappa 70 Beads should be stored under cool and dry conditions.



SYNONYM:

Carbon black beads
Degussa Printex Kappa 70
Evonik Printex Kappa 70
Kappa 70 carbon black beads
Printex K-70 beads
Printex Kappa 70 granules
Printex Kappa 70 microbeads



























PRISORINE 3501 ACID
DESCRIPTION:

Prisorine 3501 acid is our isostearic acid range, light colored, liquid fatty acid consisting of methyl branched C18 fatty acid isomers with smaller amounts of linear saturated fatty acids and oleic acid.
The low unsaturation and especially the absence of poly-unsaturation results in excellent oxidation resistance and color stability.
Prisorine 3501 acid is a long chain hydrocarbon with excellent color and thermo-oxidative stability for automotive and industrial coatings

CAS No.30399-84-9
Molecular Formula:C18H36O2
Molecular Weight:284.48

Prisorine 3501 acid is recommended for polyol esters in synthetic lubricants, for textile lubricants and hydraulic fluids among other general applications
Prisorine 3501 acid is a top grade for cosmetics esters applications
Prisorine 3501 acid is a vegetable derived recommended for less critical applications, but with oxidation stability better than oleic acid and its derivatives








BENEFITS OF PRISORINE 3501 ACID:
Flexibility - Prisorine 3501 Acid allows product to deform under stress and prevents cracking.
Prisorine 3501 Acid can also be used in conjunction with flexible substrates
Prisorine 3501 Acid is Easy to handle offering manufacturing flexibility

Prisorine 3501 Acid has Low color for low color applications and improved aesthetics
Prisorine 3501 Acid has Thermo-oxidative stability for longer product lifetime, and allowing for exposure to high temperature conditions
Pigment wetting - Prisorine 3501 Acid allows high loading of pigment/fillers which can bring cost savings



APPLICATIONS OF PRISORINE 3501 ACID:
Prisorine 3501 Acid is used in Resin modification
Prisorine 3501 Acid is used in Metallic pastes
Prisorine 3501 Acid is used in Inks

Prisorine 3501 Acid is used in Waxes and wax emulsifiers
Prisorine 3501 Acid is used in Quaternary derivatives for textile softeners and antistats

Prisorine 3501 Acid is used in Liquid stabilizers (metal soaps)
Prisorine 3501 Acid is used in Anti-corrosion additives


SAFETY INFORMATION ABOUT PRISORINE 3501 ACID:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product









CHEMICAL AND PHYSICAL PROPERTIES OF PRISORINE 3501 ACID:
vapor pressure 0Pa at 25℃
storage temp. 2-8°C
InChI InChI=1S/C18H36O2/c1-17(2)15-13-11-9-7-5-3-4-6-8-10-12-14-16-18(19)20/h17H,3-16H2,1-2H3,(H,19,20)
InChIKey XDOFQFKRPWOURC-UHFFFAOYSA-N
SMILES C(O)(=O)CCCCCCCCCCCCCCC(C)C
LogP 6.96-14.81
Dissociation constant 4.75 at 25℃


SYNONYMS OF PRISORINE 3501 ACID:
ISOOCTADECANOIC ACID
16-METHYLHEPTADECANOIC ACID
875d
emery871
emery875d
emersol875
emersol871
UCN 96.319
Unimac 5680
century1105




PRISORINE 3503 ACID
DESCRIPTION:

Prisorine 3503 acid is our isostearic acid range, light colored, liquid fatty acid consisting of methyl branched C18 fatty acid isomers with smaller amounts of linear saturated fatty acids and oleic acid.
The low unsaturation and especially the absence of poly-unsaturation results in excellent oxidation resistance and color stability.
Prisorine 3503 acid is a long chain hydrocarbon with excellent color and thermo-oxidative stability for automotive and industrial coatings

CAS No.30399-84-9
Molecular Formula:C18H36O2
Molecular Weight:284.48

Prisorine 3503 acid is recommended for polyol esters in synthetic lubricants, for textile lubricants and hydraulic fluids among other general applications
Prisorine 3503 acid is a top grade for cosmetics esters applications
Prisorine 3503 acid is a vegetable derived recommended for less critical applications, but with oxidation stability better than oleic acid and its derivatives








BENEFITS OF PRISORINE 3503 ACID:
Flexibility - Prisorine 3503 Acid allows product to deform under stress and prevents cracking.
Prisorine 3503 Acid can also be used in conjunction with flexible substrates
Prisorine 3503 Acid is Easy to handle offering manufacturing flexibility

Prisorine 3503 Acid has Low color for low color applications and improved aesthetics
Prisorine 3503 Acid has Thermo-oxidative stability for longer product lifetime, and allowing for exposure to high temperature conditions
Pigment wetting - Prisorine 3503 Acid allows high loading of pigment/fillers which can bring cost savings



APPLICATIONS OF PRISORINE 3503 ACID:
Prisorine 3503 Acid is used in Resin modification
Prisorine 3503 Acid is used in Metallic pastes
Prisorine 3503 Acid is used in Inks

Prisorine 3503 Acid is used in Waxes and wax emulsifiers
Prisorine 3503 Acid is used in Quaternary derivatives for textile softeners and antistats

Prisorine 3503 Acid is used in Liquid stabilizers (metal soaps)
Prisorine 3503 Acid is used in Anti-corrosion additives


SAFETY INFORMATION ABOUT PRISORINE 3503 ACID:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product









CHEMICAL AND PHYSICAL PROPERTIES OF PRISORINE 3503 ACID:
vapor pressure 0Pa at 25℃
storage temp. 2-8°C
InChI InChI=1S/C18H36O2/c1-17(2)15-13-11-9-7-5-3-4-6-8-10-12-14-16-18(19)20/h17H,3-16H2,1-2H3,(H,19,20)
InChIKey XDOFQFKRPWOURC-UHFFFAOYSA-N
SMILES C(O)(=O)CCCCCCCCCCCCCCC(C)C
LogP 6.96-14.81
Dissociation constant 4.75 at 25℃


SYNONYMS OF PRISORINE 3503 ACID:
ISOOCTADECANOIC ACID
16-METHYLHEPTADECANOIC ACID
875d
emery871
emery875d
emersol875
emersol871
UCN 96.319
Unimac 5680
century1105

PRISORINE 3505 ACID
DESCRIPTION:

Prisorine 3505 acid is our isostearic acid range, light colored, liquid fatty acid consisting of methyl branched C18 fatty acid isomers with smaller amounts of linear saturated fatty acids and oleic acid.
The low unsaturation and especially the absence of poly-unsaturation results in excellent oxidation resistance and color stability.
Prisorine 3505 acid is a long chain hydrocarbon with excellent color and thermo-oxidative stability for automotive and industrial coatings

CAS No.30399-84-9
Molecular Formula:C18H36O2
Molecular Weight:284.48

Prisorine 3505 acid is recommended for polyol esters in synthetic lubricants, for textile lubricants and hydraulic fluids among other general applications
Prisorine 3505 acid is a top grade for cosmetics esters applications
Prisorine 3505 acid is a vegetable derived recommended for less critical applications, but with oxidation stability better than oleic acid and its derivatives








BENEFITS OF PRISORINE 3505 ACID:
Flexibility - Prisorine 3505 Acid allows product to deform under stress and prevents cracking.
Prisorine 3505 Acid can also be used in conjunction with flexible substrates
Prisorine 3505 Acid is Easy to handle offering manufacturing flexibility

Prisorine 3505 Acid has Low color for low color applications and improved aesthetics
Prisorine 3505 Acid has Thermo-oxidative stability for longer product lifetime, and allowing for exposure to high temperature conditions
Pigment wetting - Prisorine 3505 Acid allows high loading of pigment/fillers which can bring cost savings



APPLICATIONS OF PRISORINE 3505 ACID:
Prisorine 3505 Acid is used in Resin modification
Prisorine 3505 Acid is used in Metallic pastes
Prisorine 3505 Acid is used in Inks

Prisorine 3505 Acid is used in Waxes and wax emulsifiers
Prisorine 3505 Acid is used in Quaternary derivatives for textile softeners and antistats

Prisorine 3505 Acid is used in Liquid stabilizers (metal soaps)
Prisorine 3505 Acid is used in Anti-corrosion additives


SAFETY INFORMATION ABOUT PRISORINE 3505 ACID:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product









CHEMICAL AND PHYSICAL PROPERTIES OF PRISORINE 3505 ACID:
vapor pressure 0Pa at 25℃
storage temp. 2-8°C
InChI InChI=1S/C18H36O2/c1-17(2)15-13-11-9-7-5-3-4-6-8-10-12-14-16-18(19)20/h17H,3-16H2,1-2H3,(H,19,20)
InChIKey XDOFQFKRPWOURC-UHFFFAOYSA-N
SMILES C(O)(=O)CCCCCCCCCCCCCCC(C)C
LogP 6.96-14.81
Dissociation constant 4.75 at 25℃


SYNONYMS OF PRISORINE 3505 ACID:
ISOOCTADECANOIC ACID
16-METHYLHEPTADECANOIC ACID
875d
emery871
emery875d
emersol875
emersol871
UCN 96.319
Unimac 5680
century1105





PRISORINE 3508
DESCRIPTION:
Prisorine 3508 is a vegetable-derived, light colored, liquid isostearic acid.
Prisorine 3508 consists of methyl branched C18 fatty acid isomers with smaller amounts of linear saturated fatty acids and oleic acid.
Prisorine 3508 possesses a higher iodine value and is recommended for less critical applications.

CAS No.: 30399-84-9
EC Number: 220-336-3


The low unsaturation and especially the absence of poly-unsaturation provides excellent color stability and oxidation resistance, considerably better than oleic acid and its derivatives.
Prisorine 3508 allows product to deform under stress, prevents cracking, and can also be used in conjunction with flexible substrates.
Prisorine 3508 exhibits thermo-oxidative stability for longer product lifetime, allowing for exposure to high temperature conditions.

Prisorine 3508 also imparts pigment wetting properties which allow high loading of pigment/fillers while bringing cost savings.
Prisorine 3508 is suitable for metallic pastes, inks and low color applications.
Prisorine 3508 is easy to handle and offers manufacturing flexibility and improved aesthetics.


BENEFITS OF PRISORINE 3508:
Flexibility - Prisorine 3508 allows product to deform under stress and prevents cracking.
Prisorine 3508 can also be used in conjunction with flexible substrates
Prisorine 3508 is Easy to handle offering manufacturing flexibility

Prisorine 3508 has Low color for low color applications and improved aesthetics

Prisorine 3508 has Thermo-oxidative stability for longer product lifetime, and allowing for exposure to high temperature conditions
Pigment wetting - Prisorine 3508 allows high loading of pigment/fillers which can bring cost savings


APPLICATIONS OF PRISORINE 3508:
Prisorine 3508 is used in Resin modification
Prisorine 3508 is used in Metallic pastes
Prisorine 3508 is used in Inks

Prisorine 3508 is used in Waxes and wax emulsifiers
Prisorine 3508 is used in Quaternary derivatives for textile softeners and antistats

Prisorine 3508 is used in Liquid stabilizers (metal soaps)
Prisorine 3508 is used in Anti-corrosion additives


CHEMICAL AND PHYSICAL PROPERTIES OF PRISORINE 3508:
PSA: 37.30000
XLogP3: 6.18840
Appearance: Liquid; OtherSolid, Liquid
Density: 0.888g/cm3
Melting Point: 69.3ºC
Boiling Point: 359.4ºC at 760mmHg
Flash Point: 162.4ºC
Storage Conditions: 2-8ºC
Toxicity: LDLo oral in rat: 64mL/kg
Name
Isooctadecanoic acid
EINECS 250-178-0
CAS No. 30399-84-9
Density 0.887 g/cm3
PSA 37.30000
LogP 6.18840
Melting Point 69.3oC
Formula C18H36O2
Boiling Point 400.8 °C at 760 mmHg
Molecular Weight 284.4772
Flash Point 225.6 °C
Appearance LIGHT YELLOW LIQUID



SAFETY INFORMATION ABOUT PRISORINE 3508:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product



SYNONYMS OF PRISORINE 3508:
875D
Century 1105
Emasol 873
Emersol 871
Emersol 874
Emersol 875
Emery 871
Emery 875D
Fine Oxocol 1800 Acid
Haimaric MKH(R)
IO 281
Isostearic acid 873
Isostearic acid EX
Jaric I 18CG
Prisorin ISAC 3505
Prisorine 3501
Prisorine 3502
Prisorine 3505
Prisorine 3508
UCN 96.319
Unimac 5680



PROP-2-YN-1-OL

Prop-2-yn-1-ol, also known as 2-propyn-1-ol or ethynyl alcohol, is a chemical compound with the molecular formula C3H4O.
Prop-2-yn-1-ol is an alcohol that contains a triple bond between the second carbon (C2) and the oxygen (O) atom.
Prop-2-yn-1-ol can be used in various chemical reactions and organic synthesis processes due to its unique chemical structure.
Prop-2-yn-1-ol is also known for its flammable and reactive nature, and it should be handled with care in laboratory and industrial settings.

CAS Number: 107-19-7
EC Number: 203-471-4



APPLICATIONS


Prop-2-yn-1-ol is used as a chemical intermediate in the pharmaceutical industry for synthesizing various drugs and medicines.
Prop-2-yn-1-ol is employed in the production of agrochemicals, including herbicides and pesticides.
Prop-2-yn-1-ol is utilized as a reagent in organic synthesis to introduce alkynyl functional groups into organic molecules.

Prop-2-yn-1-ol is a key component in the synthesis of acetylenic compounds, which find applications in materials science.
Prop-2-yn-1-ol is used in the preparation of specialty chemicals, such as plasticizers and surfactants.
Prop-2-yn-1-ol serves as a starting material in the synthesis of fragrances and flavor compounds in the fragrance industry.
Prop-2-yn-1-ol is employed in the production of resins, which have applications in adhesives and coatings.

Prop-2-yn-1-ol can be used as a building block for the synthesis of various organic compounds in research laboratories.
In the rubber industry, it is used in the production of rubber chemicals, enhancing the properties of rubber materials.
Prop-2-yn-1-ol can be utilized in the manufacturing of flame retardants for textiles and plastics.
Prop-2-yn-1-ol finds applications in the production of UV-curable coatings and inks used in the printing industry.
Prop-2-yn-1-ol is used in the preparation of cross-linking agents for polymers, improving their mechanical properties.
In the electronics industry, it can be employed as a precursor in the synthesis of conductive polymers.

Prop-2-yn-1-ol is used as a reagent in organic chemistry research to study reaction mechanisms.
Prop-2-yn-1-ol is sometimes used in the preparation of synthetic lubricants and hydraulic fluids.
Prop-2-yn-1-ol can be employed in the synthesis of dyes and pigments used in the textile and printing industries.
In the field of material science, it is used to modify the surface properties of materials through chemical reactions.

Prop-2-yn-1-ol can serve as a starting material for the production of specialty polymers with specific properties.
Prop-2-yn-1-ol is used in the synthesis of organic peroxides, which have applications as initiators in polymerization reactions.
Prop-2-yn-1-ol can be employed as a reactant in the preparation of insecticides used in agriculture.
In the cosmetics industry, it is used in the formulation of personal care products and cosmetics.

Prop-2-yn-1-ol is used as a research reagent for studying chemical reactions under controlled conditions.
Prop-2-yn-1-ol can be utilized in the preparation of organometallic compounds, which have applications in catalysis.

In the automotive industry, it can be used in the formulation of anti-corrosion coatings for vehicle components.
Prop-2-yn-1-ol is important in the synthesis of specialty chemicals and materials across a wide range of industries, contributing to advancements in various fields.
Prop-2-yn-1-ol is used as a reactant in the synthesis of vinyl ethers, which are important intermediates in polymer chemistry.
Prop-2-yn-1-ol serves as a building block for the preparation of acetylenic dyes and pigments used in the textile and printing industries.

Prop-2-yn-1-ol is utilized in the synthesis of specialty chemicals used in the oil and gas industry for drilling fluids and well stimulation.
Prop-2-yn-1-ol can be used in the production of fuel additives and stabilizers for improving the combustion characteristics of fuels.

Prop-2-yn-1-ol finds applications in the formulation of corrosion inhibitors for protecting metal surfaces in various industries.
Prop-2-yn-1-ol is employed in the manufacture of adhesives and sealants, contributing to the bonding of various materials.
Prop-2-yn-1-ol is used in the synthesis of cross-linking agents for polymers, enhancing their strength and durability.

Prop-2-yn-1-ol serves as a precursor in the preparation of acetylenic alcohols, which are important in the synthesis of pharmaceuticals.
Prop-2-yn-1-ol can be utilized in the production of flame retardants for plastics and textiles.

Prop-2-yn-1-ol is used in the preparation of intermediates for the production of agrochemicals and plant growth regulators.
In the construction industry, it is used as a chemical additive for improving the performance of concrete and cementitious materials.
Prop-2-yn-1-ol is employed in the formulation of inkjet printer inks, contributing to high-quality printing.
Prop-2-yn-1-ol can be used in the synthesis of propargylamines, which have applications in medicinal chemistry.
Prop-2-yn-1-ol is used in the manufacture of specialty coatings for automotive refinishing and industrial applications.

Prop-2-yn-1-ol serves as a key component in the synthesis of photoresists used in microelectronics and semiconductor manufacturing.
Prop-2-yn-1-ol can be used in the preparation of chelating ligands for coordination chemistry.

Prop-2-yn-1-ol is employed in the synthesis of alkynylsilanes, which find applications in organic and organometallic chemistry.
Prop-2-yn-1-ol is utilized in the production of surfactants and emulsifiers used in the cosmetics and personal care industry.

Prop-2-yn-1-ol can be used as a starting material for the synthesis of bioactive compounds and natural product derivatives.
Prop-2-yn-1-ol finds applications in the formulation of specialty paints and coatings for architectural and industrial use.
Prop-2-yn-1-ol is used in the preparation of organosilicon compounds, which have applications in materials science.
Prop-2-yn-1-ol can be employed in the synthesis of heterocyclic compounds for medicinal and agrochemical purposes.

Prop-2-yn-1-ol serves as a chemical reagent in the preparation of propargyl halides used in various chemical reactions.
Prop-2-yn-1-ol is used in the synthesis of metal acetylides, which are important in organometallic chemistry.
Prop-2-yn-1-ol is a versatile building block with a wide range of applications across industries, contributing to the development of new materials, chemicals, and technologies.


Prop-2-yn-1-ol is used in the production of synthetic rubber, contributing to the elasticity and durability of rubber products.
Prop-2-yn-1-ol serves as a precursor in the synthesis of propargyl ethers, which have applications in the field of organic chemistry.

Prop-2-yn-1-ol is employed in the preparation of specialty solvents used in various industrial processes.
Prop-2-yn-1-ol can be used to synthesize propargyl aldehydes and ketones, important intermediates in organic synthesis.
Prop-2-yn-1-ol finds applications in the formulation of adhesion promoters for improving bonding in composites and laminates.
Prop-2-yn-1-ol is utilized in the production of corrosion-resistant coatings for protecting metal structures and equipment.

Prop-2-yn-1-ol is used in the synthesis of photoinitiators for photopolymerization processes, such as UV curing.
Prop-2-yn-1-ol serves as a reagent in the preparation of propargyl sulfides, which have applications in medicinal chemistry.

Prop-2-yn-1-ol is used as a cross-linking agent in the formulation of epoxy resins, enhancing their performance.
Prop-2-yn-1-ol can be employed in the preparation of propargyl carbonates, which are important in the synthesis of pharmaceuticals.
Prop-2-yn-1-ol is used in the synthesis of propargyl halides, which can further react to form various organic compounds.
Prop-2-yn-1-ol serves as a building block for the preparation of propargyl boronates used in organic synthesis.

Prop-2-yn-1-ol is used as a reagent in the preparation of propargyl phosphates, important intermediates in chemical synthesis.
Prop-2-yn-1-ol can be employed in the formulation of specialty inks used in screen printing and graphic arts.
Prop-2-yn-1-ol is used in the preparation of propargyl sulfonates, which have applications in medicinal chemistry and chemical biology.
Prop-2-yn-1-ol serves as a starting material for the synthesis of propargylamines, which can be used in pharmaceutical research.
Prop-2-yn-1-ol is employed in the production of specialty adhesives for specific industrial applications.
Prop-2-yn-1-ol can be used in the preparation of propargyl acetates, which find use in organic synthesis.

Prop-2-yn-1-ol is used in the synthesis of propargyl esters, which can serve as reagents in various chemical reactions.
Prop-2-yn-1-ol serves as a reactant in the preparation of propargyl alcohols, which have applications in the synthesis of natural products.
Prop-2-yn-1-ol is used in the formulation of specialty coatings for protecting and enhancing the appearance of surfaces.

Prop-2-yn-1-ol can be employed in the synthesis of propargyl nitriles, which have applications in organic chemistry.
Prop-2-yn-1-ol is used in the production of flame retardant additives for plastics and textiles.
Prop-2-yn-1-ol serves as a reagent in the preparation of propargyl isocyanides, important in the field of organic chemistry.
Prop-2-yn-1-ol is a versatile chemical with a wide range of applications, contributing to the development of materials, pharmaceuticals, and various chemical processes in industries worldwide.
Prop-2-yn-1-ol is used in the synthesis of propargyl sulfides, which have antimicrobial properties and can be used as preservatives in personal care products.
Prop-2-yn-1-ol serves as a reactant in the preparation of propargyl azides, which are important in click chemistry reactions for the modification of biomolecules.
Prop-2-yn-1-ol can be employed in the synthesis of propargyl phosphonates, which have applications in the development of pharmaceuticals and agrochemicals.

Prop-2-yn-1-ol is used in the production of propargyl silanes, which are useful in the functionalization of silicon surfaces and the synthesis of silicon-containing compounds.
Prop-2-yn-1-ol is employed in the formulation of adhesives and sealants used in the aerospace industry for bonding critical components.
Prop-2-yn-1-ol can be used in the preparation of propargyl amides, which are versatile intermediates in organic synthesis.

Prop-2-yn-1-ol is utilized in the manufacture of propargyl glycol ethers, which are used as solvents and coupling agents in various applications.
Prop-2-yn-1-ol serves as a reagent in the synthesis of propargyl carbamates, which have applications in medicinal chemistry as potential drug candidates.
Prop-2-yn-1-ol is used in the formulation of cutting-edge resist materials for photolithography processes in semiconductor manufacturing.
Prop-2-yn-1-ol can be employed in the synthesis of propargyl hydrazines, which have applications in the field of chemical biology and drug discovery.

Prop-2-yn-1-ol is used in the preparation of propargyl thioethers, which can be used in the synthesis of complex organic molecules.
Prop-2-yn-1-ol serves as a building block for the synthesis of propargyl aziridines, which are useful in the development of biologically active compounds.
Prop-2-yn-1-ol is employed in the production of propargyl thiols, which can be used as odorants and flavorants in the food and beverage industry.

Prop-2-yn-1-ol can be used in the synthesis of propargyl carbazates, which are versatile intermediates in organic chemistry.
Prop-2-yn-1-ol is used in the formulation of specialty paints and coatings for artistic and decorative applications.
Prop-2-yn-1-ol serves as a reactant in the preparation of propargyl selenides, which have applications in the synthesis of organoselenium compounds.
Prop-2-yn-1-ol is employed in the synthesis of propargyl oximes, which can serve as building blocks in organic synthesis.
Prop-2-yn-1-ol can be used in the preparation of propargyl imidates, which are important intermediates in the synthesis of pharmaceuticals.

Prop-2-yn-1-ol is used in the formulation of specialty inks for various printing applications, including packaging and labeling.
Prop-2-yn-1-ol serves as a reagent in the synthesis of propargyl carbodiimides, which are versatile intermediates in chemical reactions.

Prop-2-yn-1-ol is employed in the production of specialty surfactants used in the formulation of cleaning products.
Prop-2-yn-1-ol can be used in the preparation of propargyl phosphinates, which have applications in the development of novel chemical compounds.
Prop-2-yn-1-ol is used in the synthesis of propargyl urethanes, which can be used as coatings for medical devices and implants.
Prop-2-yn-1-ol serves as a building block for the preparation of propargyl phosphoramidates, which are potential candidates in drug discovery.
Prop-2-yn-1-ol continues to play a vital role in a wide range of industries, contributing to advancements in chemistry, materials science, and product development.



DESCRIPTION


Prop-2-yn-1-ol, also known as 2-propyn-1-ol or ethynyl alcohol, is a chemical compound with the molecular formula C3H4O.
Prop-2-yn-1-ol is an alcohol that contains a triple bond between the second carbon (C2) and the oxygen (O) atom.
Prop-2-yn-1-ol can be used in various chemical reactions and organic synthesis processes due to its unique chemical structure.
Prop-2-yn-1-ol is also known for its flammable and reactive nature, and it should be handled with care in laboratory and industrial settings.

Prop-2-yn-1-ol is a colorless, flammable liquid at room temperature.
Prop-2-yn-1-ol is an organic compound with a unique triple bond between carbon atoms.
Prop-2-yn-1-ol is also known as ethynyl alcohol.
Prop-2-yn-1-ol has a molecular formula of C3H4O.

The IUPAC name for it is 2-propyn-1-ol.
Prop-2-yn-1-ol is soluble in water and many organic solvents.
Prop-2-yn-1-ol has a pungent, acrid odor.
Prop-2-yn-1-ol is used as a chemical intermediate in various organic syntheses.
Prop-2-yn-1-ol is important in the production of pharmaceuticals and agrochemicals.

Prop-2-yn-1-ol is a terminal alkyne, meaning the triple bond is at the end of the carbon chain.
Prop-2-yn-1-ol can undergo addition reactions with electrophiles.
It is highly reactive due to the presence of the triple bond.
In the presence of strong acids, it can be converted to other functional groups.
Prop-2-yn-1-ol is a common starting material in the synthesis of other chemicals.

Prop-2-yn-1-ol can be used as a precursor to make acetylene gas (ethyne).
Prop-2-yn-1-ol is used in the preparation of specialty chemicals.
Prop-2-yn-1-ol should be handled with caution due to its flammability.
Prop-2-yn-1-ol is employed in some organic reactions as a nucleophile.

In the laboratory, it is often used in organic chemistry experiments.
Prop-2-yn-1-ol has a low boiling point, making it easily vaporizable.
Prop-2-yn-1-ol can form hydrogen bonds with water molecules.
Prop-2-yn-1-ol is sometimes used in the production of plastics and resins.

Prop-2-yn-1-ol has applications in the manufacturing of rubber chemicals.
In industry, it may be utilized in the synthesis of pesticides.
Proper safety measures and protective equipment should be used when handling Prop-2-yn-1-ol due to its reactivity and potential hazards.



PROPERTIES


Physical Properties:

Molecular Formula: C3H4O
Molecular Weight: 56.06 g/mol
Physical State: Colorless liquid
Odor: Pungent and acrid
Melting Point: -69.2 °C (-92.6 °F)
Boiling Point: 81.6 °C (178.9 °F)
Density: 0.865 g/cm³ at 20 °C
Solubility: Soluble in water and many organic solvents
Flash Point: -18 °C (-0.4 °F)
Vapor Pressure: 19 mm Hg at 20 °C


Chemical Properties:

Functional Group: Terminal alkyne (-C≡C) and hydroxyl (-OH) group
Reactivity: Highly reactive due to the presence of a triple bond (alkyne)
pH: Typically neutral when dissolved in water
Flammability: Flammable and can form explosive mixtures with air
Miscibility: Miscible with many organic solvents, including acetone, ether, and ethanol



FIRST AID


Inhalation:

If inhaled, move the affected person to fresh air immediately, away from the source of exposure.
Keep the person calm and encourage deep breaths.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing and does not have a pulse, begin CPR (cardiopulmonary resuscitation) and continue until medical professionals arrive.


Skin Contact:

Remove contaminated clothing and shoes if they come into contact with Prop-2-yn-1-ol.
Wash the affected skin area gently with plenty of water for at least 15 minutes.
Use mild soap to cleanse the skin, but do not scrub vigorously.
Seek medical attention if irritation, redness, or chemical burns develop.


Eye Contact:

Immediately rinse the affected eye(s) with gently flowing lukewarm water for at least 15 minutes, holding the eyelid(s) open to ensure thorough rinsing.
Remove contact lenses if present and easy to do so after the initial rinse.
Continue rinsing while seeking immediate medical attention from an eye specialist.
Do not delay medical treatment, even if symptoms seem minor, as eye injuries can worsen over time.


Ingestion:

If Prop-2-yn-1-ol is ingested accidentally, do not induce vomiting unless instructed to do so by medical personnel.
Do not give anything by mouth to an unconscious person.
Seek immediate medical attention or contact a poison control center for guidance.


General First Aid:

If there are any signs of discomfort, irritation, or adverse health effects after exposure to Prop-2-yn-1-ol, seek medical attention promptly.
Provide the medical personnel with information about the chemical, including its name, CAS number, and the circumstances of exposure.
If assisting someone exposed to the chemical, ensure that you are also safe from exposure and follow appropriate personal protective measures, such as wearing gloves and eye protection.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):

Always wear appropriate personal protective equipment (PPE) when handling Prop-2-yn-1-ol.
This may include but is not limited to:
Chemical-resistant gloves
Safety goggles or a face shield to protect the eyes
A lab coat or chemical-resistant apron
Closed-toe shoes with chemical-resistant soles
A chemical-resistant apron or lab coat
Respiratory protection if ventilation is inadequate or exposure levels are high

Ventilation:

Work with Prop-2-yn-1-ol in a well-ventilated area, such as a chemical fume hood, to minimize inhalation exposure.
Ensure that the ventilation system effectively removes vapors and maintains a safe working environment.

Avoidance of Contact:

Minimize skin and eye contact with the chemical.
Use appropriate PPE to prevent accidental contact.

Handling Precautions:

Use caution when transferring or pouring Prop-2-yn-1-ol to prevent spills or splashes.
Do not eat, drink, or smoke while handling the chemical.

Labeling:

Ensure that containers holding Prop-2-yn-1-ol are properly labeled with its name, hazard warnings, and safety information.


Storage:

Storage Area:

Store Prop-2-yn-1-ol in a dedicated storage area away from incompatible materials, such as strong acids, strong bases, and strong oxidizing agents.
Keep the storage area cool, dry, and well-ventilated.

Container Selection:

Use containers made of materials compatible with Prop-2-yn-1-ol, such as glass or chemical-resistant plastics (e.g., high-density polyethylene).
Ensure that containers are tightly sealed to prevent leaks or evaporation.

Separation from Incompatibles:

Keep Prop-2-yn-1-ol separated from incompatible chemicals and substances to avoid potential reactions or hazards.

Flammability Precautions:

Store away from open flames, heat sources, and ignition sources.
Ensure that there are no smoking or open flame sources in the storage area.

Labeling and Identification:

Clearly label all containers with the chemical's name, hazard information, and storage instructions.
Consider using color-coded labels or hazard signs to easily identify the contents.

Storage Temperature:

Store Prop-2-yn-1-ol at the appropriate temperature, which is typically room temperature (20-25°C or 68-77°F).

Spill Containment:

Have spill containment materials, such as absorbent materials and spill kits, readily available in the storage area.

Security Measures:

Limit access to the storage area to authorized personnel only.
Implement security measures to prevent unauthorized access or tampering.



SYNONYMS


Ethynyl alcohol
2-Propyn-1-ol
Ethynylcarbinol
Ethinylcarbinol
Acetylenyl alcohol
Propargyl alcohol
Hydroxyacetylene
Propinol
Ethynol
1-Hydroxy-2-propyne
2-Hydroxy-1-propyne
Ethinylmethanol
1-Propin-1-ol
1-Propyne-1-ol
Vinyl carbinol
Methyl ketene
Propargyl hydroxide
Acetylenemethanol
Ethinol
Ethynylmethanol
Ethinylethanol
Ethynylcarbinol
Propargyl alcohol
Ethynylmethanol
2-Propynol
Propargyl methanol
Hydroxyethyne
1-Hydroxypropyne
1-Propyne-1-ol
Propynyl alcohol
Hydroxylethyne
Acetylenecarbinol
1-Hydroxy-2-propyne
Ethynyl ethyl alcohol
Methyl ethynyl carbinol
Acetylenylmethanol
Ethynyl ethylmethanol
Propynylmethanol
Acetylene ethanol
Methyl acetylenol
Ethynylmethanol
Acetylene carbinol
2-Hydroxypropyne
Ethynyl carbinol
2-Propin-1-ol
Prop-2-yn-1-yl alcohol
1-Ethynyl-1-hydroxyethane
Ethinylmethylethanol
Ethynylcarbinol
Acetylenylmethanol
Ethynylmethylethyl alcohol
Methyl ethynylmethanol
Propargylcarbinol
Hydroxyacetylenemethane
Ethynyl alcohol
Propynylmethylethanol
Ethinylmethylethanol
Acetylenyl ethyl alcohol
Ethinylmethylethyl alcohol
1-Hydroxy-2-propyne
1-Ethynyl-1-hydroxy-ethane
Acetylenylmethylcarbinol
Propynylmethylmethanol
2-Propynylalcohol
Ethinyl ethylmethanol
PROPAN-1-OL (n-PROPANOL)
Propan-1-ol (n-propanol) is a primary alcohol with the formula CH3CH2CH2OH.
Propan-1-ol (n-propanol) is miscible with water, ethanol and ether.
Propan-1-ol (n-propanol) is a colourless liquid and an isomer of 2-propanol.


CAS Number: 71-23-8
EC Number: 200-746-9
MDL Number: MFCD00002941
Molecular Formula: C3H8O / CH3CH2CH2OH



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optal, 1-hydroxypropane, osmosol extra, Propylic alcohol, Propanol-1, 1-Propyl alcohol, n-Propan-1-ol, Propanole, Propanolen, Alcohol, propyl,
Propanoli, Ethyl carbinol, Alcool propylique, Propylowy alkohol, n-Propyl alkohol, Albacol, 142583-61-7, propane-1-ol, 1-PROPONOL, propylalcohol, Propyl alcohol, normal Caswell No. 709A, FEMA No. 2928, FEMA Number 2928, Propyl alcohol (natural), Propyl alcohol, n-, Propyl-d7 alcohol, NSC 30300, CCRIS 3202, HSDB 115, n-Propylalkohol, EINECS 200-746-9, EPA Pesticide Chemical Code 047502, n-PrOH, UNII-96F264O9SV, BRN 1098242, DTXSID2021739, CHEBI:28831, AI3-16115, Propylan-propyl alcohol, 96F264O9SV, Propyl-1,1-d2 alcohol, MFCD00002941, NSC-30300, 62309-51-7, UN 1274, Propyl-3,3,3-d3 alcohol, DTXCID001739,
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Q14985, A837125, InChI=1/C3H8O/c1-2-3-4/h4H,2-3H2,1H, J-505102, 1-Propanol, for inorganic trace analysis, >=99.8%, F0001-1829, 1-Propanol, puriss. p.a., Reag. Ph. Eur., >=99.5% (GC), 1-Propanol, United States Pharmacopeia (USP) Reference Standard, n-Propanol or propyl alcohol, normal [UN1274], 5VQ, Propan-1-ol Other Names: n-Propyl alcohol, n-Propanol, n-PrOH, Ethylcarbinol, 1-Hydroxypropane, Propionic alcohol, Propionyl alcohol, Propionylol, Propyl alcohol, Propylic alcohol, Propylol, (1-hydroxypropane, 1-propanol, anhydrous, alcohol C3, ethyl carbinol, normal-propanol, normal-propyl alcohol, n-propanol, n-propanol (propyl alcohol, normal), OPTAL, OS MOSOL, osmosol extra, propan-1-ol, propanol, propyl alcohol, propyl alcohol, normal, propylic alcohol, Propyl alcohol, n-Propan-1-ol, n-Propanol, n-Propyl alcohol, Ethylcarbinol, Optal, Osmosol extra, Propanol, Propylic alcohol, 1-Propyl alcohol, n-C3H7OH, 1-Hydroxypropane, Propanol-1, Propan-1-ol, n-Propyl alkohol, Alcool propilico, Alcool propylique, Propanole, Propanolen, Propanoli, Propylowy alkohol, UN 1274, Propylan-propyl alcohol, NSC 30300, Alcohol, propyl, n-C3H7OH, Propanol, 1-Propanol, n-Propanol, Propan-1-ol, Propyl Alcohol, femanumber2928, ethyl carbinol, alcoolpropilico, n-propyl alcohol, n-ppropylalcohol, alcoolpropylique, Natural Propyl Alcohol, epapesticidechemicalcode047502, 1 Propanol, 1-Hydroxypropane, 1-Propanol, 1-Propyl alcohol, Alcohol, propyl, Ethyl carbinol, Ethylcarbinol, Hydroxypropane, N Propanol, N-Propan-1-ol, n-Propyl alcohol, n-Propanol, n-PrOH, Ethyl carbinol, 1-Hydroxypropane, Propionic alcohol, Propionyl alcohol, Propionylol, Propyl alcohol, Propylic alcohol, Propylol, 1-Hydroxypropane, 1-Propyl alcohol, Alcohol, propyl, Alcool propilico, Alcool propylique, Ethylcarbinol, N-PROPYL ALCOHOL, NSC 30300, Optal, Osmosol extra, PROPYL ALCOHOL, Propan-1-ol, Propanol, Propanol-1, Propanole, Propanolen, Propanoli, Propylan-propyl alcohol, Propylic alcohol, Propylowy alkohol, UN 1274, n-C3H7OH, n-Propan-1-ol, n-Propanol, n-Propyl alkohol, 1-propanol, propanol, n-propanol, Propyl alcohol, Propan-1-ol, n-Propyl alcohol, ethylcarbinol, 1-hydroxypropane, 1-Hydroxypropane, 1-propanol, 1-Propanol, ethyl carbinol, Ethylcarbinol, n-propan-1-ol, n-Propanol, N-PROPANOL, n-Propyl alcohol, n-Propylalkohol, Optal, Osmosol extra, propan-1-ol, Propan-1-ol, Propane-1-ol, Propanol, propanol-1, Propyl alcohol, UN 1274,



Propan-1-ol (n-propanol) is colorless clear liquid with ethanol-like odor.
Propan-1-ol (n-propanol) is with water, alcohol, ether, hydrocarbon and other solvents miscible.
The chemical properties of Propan-1-ol (n-propanol) are similar to those of other low molecular weight aliphatic primary alcohols.


Propan-1-ol (n-propanol) is miscible with water, ethanol and ether.
Propan-1-ol (n-propanol), also known as propanol or ethylcarbinol, is a member of the class of compounds known as primary alcohols.
Primary alcohols are compounds comprising the primary alcohol functional group, with the general structure RCOH (R=alkyl, aryl).


Thus, Propan-1-ol (n-propanol) is considered to be a fatty alcohol lipid molecule.
Propan-1-ol (n-propanol) is soluble (in water) and an extremely weak acidic compound (based on its pKa).
Propan-1-ol (n-propanol) can be found in a number of food items such as cashew nut, chinese mustard, greenthread tea, and chayote, which makes propyl alcohol a potential biomarker for the consumption of these food products.


Propan-1-ol (n-propanol) can be found primarily in blood, feces, and saliva, as well as in human fibroblasts tissue.
Propan-1-ol (n-propanol) exists in all eukaryotes, ranging from yeast to humans.
In humans, Propan-1-ol (n-propanol) is involved in the sulfate/sulfite metabolism.


Propan-1-ol (n-propanol) is also involved in sulfite oxidase deficiency, which is a metabolic disorder.
Propan-1-ol (n-propanol) belongs to the class of organic compounds known as primary alcohols.
Primary alcohols are compounds comprising the primary alcohol functional group, with the general structure RCOH (R=alkyl, aryl).


Propan-1-ol (n-propanol) is a primary alcohol with the formula CH3CH2CH2OH and sometimes represented as PrOH or n-PrOH.
Propan-1-ol (n-propanol) is a colourless liquid and an isomer of 2-propanol.
Propan-1-ol (n-propanol) is a primary alcohol with the formula CH3CH2CH2OH.


This colorless liquid, Propan-1-ol (n-propanol), is also known as propan-1-ol, 1-propyl alcohol, n-propyl alcohol, n-propanol, or simply propanol.
Propan-1-ol (n-propanol) is an isomer of isopropanol (2-propanol, isopropyl alcohol).
Propan-1-ol (n-propanol) has high octane numbers and it is suitable for engine fuel usage.


However, the production of Propan-1-ol (n-propanol) has been too expensive to make it a common fuel.
The research octane number (RON) of Propan-1-ol (n-propanol) is 118 and anti-knock index (AKI) is 108.
Propan-1-ol (n-propanol) is formed naturally in small amounts during many fermentation processes.


Propan-1-ol (n-propanol) is a primary alcohol with the formula CH3CH2CH2OH.
Propan-1-ol (n-propanol) is also known as 1-propanol, 1-propyl alcohol, n-propyl alcohol, or simply propanol.
Propan-1-ol (n-propanol) is an isomer of propan-2-ol.


Propan-1-ol (n-propanol) (also propan-1-ol, propanol, n-propyl alcohol) is a primary alcohol with the formula CH3CH2CH2OH and sometimes represented as PrOH or n-PrOH.
Propan-1-ol (n-propanol) is a colourless liquid and an isomer of 2-propanol.


Propan-1-ol (n-propanol) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Propan-1-ol (n-propanol) appears as a clear colorless liquid with a sharp musty odor like rubbing alcohol.


Flash point of Propan-1-ol (n-propanol) is 53-77 °F.
Propan-1-ol (n-propanol) vapors are heavier than air and mildly irritate the eyes, nose, and throat.
Propan-1-ol (n-propanol) is the parent member of the class of propan-1-ols that is propane in which a hydrogen of one of the methyl groups is replaced by a hydroxy group.


Propan-1-ol (n-propanol) has a role as a protic solvent and a metabolite.
Propan-1-ol (n-propanol) is a short-chain primary fatty alcohol and a member of propan-1-ols.
Propan-1-ol (n-propanol) is a colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.


Propan-1-ol (n-propanol) is a natural product found in Aloe africana, Cichorium endivia, and other organisms with data available.
Propan-1-ol (n-propanol) is a metabolite found in or produced by Saccharomyces cerevisiae.
Propan-1-ol (n-propanol) is a primary alcohol in which the OH entity is bonded to a primary carbon atom.


Propan-1-ol (n-propanol) (CH3CH2CH2OH) is one of two isomers of propanol (C3H8O); the other is 2-propanol ((CH3)2CHOH).
Propan-1-ol (n-propanol) is a clear, colourless transparent liquid that has a typical sharp musty odour that is comparable with the smell of rubbing alcohol.


Propan-1-ol (n-propanol)belongs to the class of organic compounds known as primary alcohols.
Primary alcohols are compounds comprising the primary alcohol functional group, with the general structure RCOH (R=alkyl, aryl).
Propan-1-ol (n-propanol) is one of the most common types of alcohol.


Propan-1-ol (n-propanol) has the formula CH3CH2CH2OH.
Propan-1-ol, n-propyl alcohol, 1-propyl alcohol, or n-propanol are all names for this colourless oil.
Alcohols are those organic compounds which are characterised by the presence of one, two or more hydroxyl groups (−OH) that are attached to the carbon atom in an alkyl group or hydrocarbon chain.


Propan-1-ol (n-propanol) is the parent member of the class of propan-1-ols that is propane in which a hydrogen of one of the methyl groups is replaced by a hydroxy group.
Propan-1-ol (n-propanol) has a role as a protic solvent and a metabolite.


Propan-1-ol (n-propanol) is a short-chain primary fatty alcohol and a member of propan-1-ols.
Propan-1-ol (n-propanol) appears as a clear colorless liquid with a sharp musty odor like rubbing alcohol.
Propan-1-ol (n-propanol) appears as a clear colorless liquid with a sharp musty odor like rubbing alcohol.


Propan-1-ol (n-propanol) is a low molecular weight alcohol that is currently being investigated as an alternative fuel for direct methanol/oxygen fuel cells.
Propan-1-ol (n-propanol) is a colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.


Propan-1-ol (n-propanol) is a primary alcohol with a molecular formula of CH3(CH2)2OH.
Propan-1-ol (n-propanol) is a colourless, transparent liquid that has a typical sharp musty odor that is comparable with the smell of rubbing alcohol.
Propan-1-ol (n-propanol) is fully miscible in water and freely miscible with all common solvents such as glycols, ketones, alcohols, aldehydes, ethers and aliphatic hydrocarbons.


Propan-1-ol (n-propanol) has a flash point of around 15° C and improves drying in coating applications.
Propan-1-ol (n-propanol) is a compound in which one hydrogen atom in the propane molecule is replaced by a hydroxyl group.
Since the hydroxyl group can replace hydrogen on both ends of the carbon chain or the intermediate carbon atom, two isomers of N-Propan-1-ol (n-propanol) and isopropanol can be formed.


The chemical properties of Propan-1-ol (n-propanol) and ethanol similar to carbon monoxide and hydrogen synthesis of methanol by-products, at room temperature and atmospheric pressure, are colorless transparent liquid, fragrance.
In industry, Propan-1-ol (n-propanol) is prepared from ethylene, carbon monoxide and hydrogen under high pressure and cobalt catalysis, and it is prepared from propylene in the action of sulfuric acid or from acetone by catalytic hydrogenation reaction.


Propan-1-ol (n-propanol) also known as n-propanol, n-propyl alcohol, propionic alcohol and propylol has the chemical formula CH3CH2CH2OH.
Like other alcohols, Propan-1-ol (n-propanol) has a hydroxy group, —OH, attached to a saturated carbon atom.
Propan-1-ol (n-propanol) can be abbreviated as PrOH or (n-PrOH).


Propan-1-ol (n-propanol) is a colorless liquid at room temperature and pressure.
Like other alcohols, Propan-1-ol (n-propanol) can have hydrogen bonds between its molecules which strengthen its intermolecular interactions and result in much higher values of physical properties like melting and boiling points in comparison to many other organic and inorganic substances with similar molecular weights.


For example, while Propan-1-ol (n-propanol) boils at 97 °C, methoxyethane (CH3OCH2CH3) with the same molecular weight but no hydrogen bonds between its molecules boils at 7.4 °C.
Like other alcohols, Propan-1-ol (n-propanol) has both a hydrophilic (literally water loving) group, which is the hydroxy group (—OH), and a hydrophobic (lipophilic or literally fat loving) group which is the propyl group (—CH2CH2CH3).


In addition to Propan-1-ol (n-propanol), another alcohol, 2-propanol or propan-2-ol, exists with the molecular formula of C3H8O which has its hydroxy group attached to the middle carbon (it has the form CH3CHOHCH3).
These two alcohols, propan-1-ol and propan-2-ol, in a broad sense are constitutional (structural) isomers of each other.


In a more specific way, they are position isomers (positional isomers) of each other.
One should note that by constitutional isomerism we mean isomerism between structures differing in constitution like CH3CH2CH2OH, CH3CHOHCH3 and CH3CH2OCH3 as constitutional isomers of each other; while by position isomerism (regioisomerism) we mean isomerism between structures differing in the position of a functional group or substituent on a same parent structure like CH3CH2CH2OH and CH3CHOHCH3 as positional isomers of each other.


Position isomerism can be considered as a specific form of constitutional isomerism.
Propan-1-ol (n-propanol) has some applications like its use as a solvent in the pharmaceutical industry.
Propan-1-ol (n-propanol) is industrially produced by catalytic hydrogenation of propanal (CH3CH2CH=O + H2 —> CH3CH2CH2OH) where propanal itself is obtained from the hydroformylation or oxo reaction of ethylene, carbon monoxide and hydrogen together (H2C=CH2 + CO + H2 —> CH3CH2CH=O).


Propan-1-ol (n-propanol) can also be produced naturally in small amounts by fermentation processes.
Considering its octane number and anti-knock index, Propan-1-ol (n-propanol) is suitable for engine fuel usage which is hindered by its price.



USES and APPLICATIONS of PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is formed naturally in small amounts during many fermentation processes and used as a solvent in the pharmaceutical industry mainly for resins and cellulose esters.
Propan-1-ol (n-propanol) has high octane numbers and it is suitable for engine fuel usage.


Propan-1-ol (n-propanol) is used as a solvent in the pharmaceutical industry, and for resins and cellulose esters.
Propan-1-ol (n-propanol) is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Propan-1-ol (n-propanol) is approved for use as a biocide in the EEA and/or Switzerland, for: human hygiene, disinfection, food and animals feeds.
Propan-1-ol (n-propanol) is used in the following products: lubricants and greases, anti-freeze products, coating products, finger paints, washing & cleaning products, adhesives and sealants, polishes and waxes and perfumes and fragrances.


Other release to the environment of Propan-1-ol (n-propanol) is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Other release to the environment of Propan-1-ol (n-propanol) is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Propan-1-ol (n-propanol) can be found in products with material based on: wood (e.g. floors, furniture, toys).
Propan-1-ol (n-propanol) is used in the following products: coating products, laboratory chemicals, washing & cleaning products, lubricants and greases, metal working fluids and plant protection products.


Propan-1-ol (n-propanol) is used in the following areas: scientific research and development and health services.
Propan-1-ol (n-propanol) is used for the manufacture of: fabricated metal products, electrical, electronic and optical equipment, machinery and vehicles and textile, leather or fur.


Other release to the environment of Propan-1-ol (n-propanol) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Propan-1-ol (n-propanol) is used in the following products: coating products and inks and toners.
Release to the environment of Propan-1-ol (n-propanol) can occur from industrial use: formulation of mixtures, manufacturing of the substance, formulation in materials and in processing aids at industrial sites.


Propan-1-ol (n-propanol) is used in the following products: laboratory chemicals, coating products, pharmaceuticals, washing & cleaning products, lubricants and greases and metal working fluids.
Propan-1-ol (n-propanol) has an industrial use resulting in manufacture of another substance (use of intermediates).


Propan-1-ol (n-propanol) is used in the following areas: health services and formulation of mixtures and/or re-packaging.
Propan-1-ol (n-propanol) is used for the manufacture of: chemicals.
Release to the environment of Propan-1-ol (n-propanol) can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release and manufacturing of the substance.


Release to the environment of Propan-1-ol (n-propanol) can occur from industrial use: manufacturing of the substance, formulation of mixtures and in processing aids at industrial sites.
Density of Propan-1-ol (n-propanol) approximately is 6.5 lb / gal.


Propan-1-ol (n-propanol) is used in making cosmetics, skin and hair preparations, pharmaceuticals, perfumes, lacquer formulations, dye solutions, antifreezes, rubbing alcohols, soaps, window cleaners, acetone and other chemicals and products.
Propan-1-ol (n-propanol) is formed naturally in small amounts during many fermentation processes and used as a solvent in the pharmaceutical industry, mainly for resins and cellulose esters, and, sometimes, as a disinfecting agent.


Pharmaceuticals, floor polishes, dental lotions, lacquers, printing inks, natural gums, pigments, intermediates, dye solutions, antifreeze, gasoline additives, paint additives, and degreasing fluids all use Propan-1-ol (n-propanol) as a solvent.
Propan-1-ol (n-propanol) has low acute toxicity for animals when administered via the dermal, inhalation, or oral routes; it is not irritating to the skin, and dermal absorption is expected to be sluggish. n-Propan-1-ol (n-propanol) is easily metabolized and has no carcinogenic or mutagenic properties.


Propan-1-ol (n-propanol) is used as a solvent, in many cases can replace the lower boiling point of ethanol.
Propan-1-ol (n-propanol) is also used as a coupling and dispersing agent in the pharmaceutical and chemicals industries.
Propan-1-ol (n-propanol) is used in making cosmetics, skin and hair preparations, pharmaceuticals, perfumes, lacquer formulations, dye solutions, antifreezes, rubbing alcohols, soaps, window cleaners, acetone and other chemicals and products.


Propan-1-ol (n-propanol) is used in making cosmetics, skin and hair preparations, pharmaceuticals, perfumes, lacquer formulations, dye solutions, antifreezes, rubbing alcohols, soaps, window cleaners, acetone and other chemicals and products.
Propan-1-ol (n-propanol) is used as a solvent or to make other solvents including antifreezes, lacquer formulas, soaps, dye solutions, and window cleaners.


In the printing industry and in printing ink, Propan-1-ol (n-propanol) compounds such as isopropanol or isopropyl alcohol are most widely used.
In pharmaceutics, hospitals, clean rooms, and electronics or medical device manufacturing, Propan-1-ol (n-propanol) is the most popular and widely used disinfectant.


Tremors, angina (chest pain), hypertension (high blood pressure), heart rhythm problems, and other heart or circulatory issues are treated with Propan-1-ol (n-propanol).
Propan-1-ol (n-propanol)’s also used to treat or avoid heart attacks, as well as to lessen the severity and frequency of migraines.


Propan-1-ol (n-propanol), also known as n-propyl alcohol or 1-propanol, is one of two isomeric alcohols used in chemical processing as solvents and intermediates.
Propan-1-ol (n-propanol) is most commonly used as a solvent in cosmetics and pharmaceuticals, as well as in lacquer preparation.


Propan-1-ol (n-propanol) produces a variety of esters and ethers, some of which are commercially valuable.
Propan-1-ol (n-propanol) is generally used as a solvent.
Propan-1-ol (n-propanol) is a good solvent, can be directly or through the synthesis of propyl acetate for coating, printing ink, daily chemical products and other fields.


N-propylamine, propylacetate, propylurea, 2-methyl-2-pentanol, n-bromopropane, perfluoropropionic acid, propylparaben and propylparaben can be synthesized from Propan-1-ol (n-propanol).
Propan-1-ol (n-propanol) in the pharmaceutical industry for the production of probenecid, sodium valproate, erythromycin, propylamine sulfate, 2, 5-pyridinedicarboxylic acid dipropyl ester.


The most important derivative of Propan-1-ol (n-propanol) is N-propylamine, which is mainly used in the production of pesticides such as azulene, endazole, isopropramine, trifluralin, and caecones.
Propan-1-ol (n-propanol) can also be produced naturally in small amounts by fermentation processes.


Considering its octane number and anti-knock index, Propan-1-ol (n-propanol) is suitable for engine fuel usage which is hindered by its price.
Propan-1-ol (n-propanol) is used solvent, desinfective agent, analytical reagent, substrate for organic syntheses.
Propan-1-ol (n-propanol) is formed naturally in small amounts during many fermentation processes and used as a solvent in the pharmaceutical industry, mainly for resins and cellulose esters, and, sometimes, as a disinfecting agent.


Propan-1-ol (n-propanol) is generally used as a solvent, is also the preparation of N-propylamine and other raw materials.
Propan-1-ol (n-propanol) is used as chromatographic analysis reagents, solvents and cleaning agents.
Propan-1-ol (n-propanol) is used extraction solvents; GB 27601996: food flavors, food processing aids..


Propan-1-ol (n-propanol) is directly used as a solvent or synthesis of propyl acetate, used in Coating solvents, printing inks, cosmetics, etc.
Propan-1-ol (n-propanol) is used in the production of pharmaceuticals, pesticide intermediates N-propylamine, used in the production of feed additives, synthetic spices, etc.


Propan-1-ol (n-propanol) is used in the pharmaceutical industry for the production of probenecid, sodium valproate, erythromycin, Jiantian, adhesive hemostatic agent BCA, propylthiamine, 2, 5-pyridinedicarboxylic acid dipropyl Ester, etc, used in food additives, plasticizers, spices and many other aspects; Propan-1-ol (n-propanol) derivatives, especially di-n-propylamine in medicine, pesticide production has many applications, used to produce pesticide sulfamethoxazole, bacteria killing, isopropylamine, maimao, sulfolin, flumol, etc.


Propan-1-ol (n-propanol) is used as a solvent, in many cases can replace the lower boiling point of ethanol.
Propan-1-ol (n-propanol) is used solvents and cleaning agents for vegetable oils, natural rubber, resins and cellulose esters.
Propan-1-ol (n-propanol) is generally used as a solvent.


Propan-1-ol (n-propanol) can be used in Coating solvents, printing inks, cosmetics, etc., for the production of pharmaceuticals, pesticides, intermediates for the production of N-propylamine, for the production of feed additives, synthetic spices.
Propan-1-ol (n-propanol) in the pharmaceutical industry, food additives, plasticizers, spices and many other areas have a wide range of applications.


-Propan-1-ol (n-propanol) is used as fuel:
Propan-1-ol (n-propanol) has high octane number and is suitable for engine fuel usage.
However, Propan-1-ol (n-propanol) is too expensive to use as a motor fuel.
The research octane number (RON) of Propan-1-ol (n-propanol) is 118, and anti-knock index (AKI) is 108.


-Industry Uses of Propan-1-ol (n-propanol):
Propan-1-ol (n-propanol) is used as a solvent in the manufacturing of pharmaceuticals, polishes, dental lotions, coatings, lacquers, printing inks, natural gums, pigments, intermediates, dye solutions, antifreeze, fuel additives, paint additives and de-greasing fluids.

Propan-1-ol (n-propanol) is also used as a chemical intermediate to create esters, halides, propyl amines and propyl acetate.
The end-user markets of Propan-1-ol (n-propanol) are the cosmetics, cleaning, motor, printing, coatings and chemical industries.
Propan-1-ol (n-propanol) is also used as fuel in engines due to its high-octane count.

However, due to its expensive nature and low energy gains, Propan-1-ol (n-propanol) is not commonly used.
Commercial Uses: Propan-1-ol (n-propanol) is used as a solvent in antifoaming in cosmetics, perfumes, flavours, fragrances, air care products, cleaning and furnishing products, paints, coatings, inks, personal care products, soaps and window cleaner.



STRUCTURE OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is one of the most common types of alcohol.
Propan-1-ol (n-propanol) has the formula CH3CH2CH2OH.
Propan-1-ol, n-propyl alcohol, 1-propyl alcohol, or n-propanol are all names of this colourless oil.



PREPARATION OF PROPAN-1-OL (n-PROPANOL):
*From Propionaldehyde:
Propionaldehyde is catalytically hydrogenated to produce Propan-1-ol (n-propanol).
Propionaldehyde is made by hydroformylation ethylene with carbon monoxide and hydrogen in the presence of a catalyst like cobalt octacarbonyl or a rhodium complex in the oxo phase.

H2C=CH2 + CO + H2 → CH3CH2CH=O
CH3CH2CH=O + H2 → CH3CH2CH2OH

The synthesis of methanol (methyl alcohol) from carbon monoxide and hydrogen produces propyl alcohol as a by-product.
Propan-1-ol (n-propanol) can also be found in fusel oil.
Propan-1-ol (n-propanol) is most commonly used as a solvent in cosmetics and pharmaceuticals, as well as in lacquer preparation.
Propan-1-ol (n-propanol) is a colourless, flammable, and aromatic liquid that is miscible in all proportions with water and is moderately toxic.



CHEMICAL AND PHYSICAL PROPERTIES OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is colorless, transparent liquid with pungent scent, inflammable, soluble in water and ethanol.



CHEMICAL PROPERTIES OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) shows the normal reactions of a primary alcohol.
Thus Propan-1-ol (n-propanol) can be converted to alkyl halides; for example red phosphorus and iodine produce 1-iodopropane in 90% yield, while PCl3 with catalytic ZnCl2 gives 1-chloropropane.

Reaction with acetic acid in the presence of an H2SO4 catalyst under Fischer esterification conditions gives propyl acetate, while refluxing Propan-1-ol (n-propanol) overnight with formic acid alone can produce propyl formate in 65% yield.
Oxidation of Propan-1-ol (n-propanol)with Na2Cr2O7 and H2SO4 gives only a 36% yield of propionaldehyde, and therefore for this type of reaction higher yielding methods using PCC or the Swern oxidation are recommended.

Oxidation of Propan-1-ol (n-propanol) with chromic acid yields propionic acid.
Some example reactions of 1-propanol:
Propan-1-ol (n-propanol) shows the normal reactions of a primary alcohol.

Thus Propan-1-ol (n-propanol) can be converted to alkyl halides; for example red phosphorus and iodine produce n-propyl iodide in 80% yield, while PCl3 with catalytic ZnCl2 gives n-propyl chloride.
Reaction with acetic acid in the presence of an H2SO4 catalyst under Fischer esterification conditions gives propyl acetate, while refluxing propanol overnight with formic acid alone can produce propyl formate in 65% yield.

Oxidation of Propan-1-ol (n-propanol) with Na2Cr2O7 and H2SO4 gives a 36% yield of propionaldehyde, and therefore for this type of reaction higher yielding methods using PCC or the Swern oxidation are recommended.
Oxidation with chromic acid yields propionic acid.



PREPARATION OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is manufactured by catalytic hydrogenation of propionaldehyde.
Propionaldehyde is produced via the oxo process by hydroformylation of ethylene using carbon monoxide and hydrogen in the presence of a catalyst such as cobalt octacarbonyl or a rhodium complex.

H2C=CH2 + CO + H2 → CH3CH2CH=O
CH3CH2CH=O + H2 → CH3CH2CH2OH
A traditional laboratory preparation of Propan-1-ol (n-propanol) involves treating n-propyl iodide with moist Ag2O.



ALTERNATIVE PARENTS OF PROPAN-1-OL (n-PROPANOL):
*Hydrocarbon derivatives



SUBSTITUENTS OF PROPAN-1-OL (n-PROPANOL):
*Hydrocarbon derivative
*Primary alcohol
*Aliphatic acyclic compound



PRODUCTION METHODS OF PROPAN-1-OL (n-PROPANOL):
*Recovery method from isopropanol by-products when propylene is directly hydrated to isopropanol, the by-product is N-propanol, from which the n-propanol is recovered.

*Hydrogenation of propylene oxide.
Propionaldehyde hydrogenation method from propionaldehyde, acrolein hydrogenation of N-propanol and allyl alcohol.

*Hydrogenation of allyl alcohol.

*Methanol method.
Oxo-ethene synthesis.
Derived from the oxidation of natural gas by carbon hydride.
Made from fusel oil.



PHYSICAL AND CHEMICAL PROPERTIES OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is a colorless transparent liquid.
Propan-1-ol (n-propanol) has an ethanol-like odor.
Propan-1-ol (n-propanol) is a small amount is present in the fusel oil.

Density 0.8036.
Refractive index 1.3862.
Melting Point -127 °c.

Boiling point 97.19 °c.
Propan-1-ol (n-propanol) is soluble in water, ethanol and ether.
The vapor forms of Propan-1-ol (n-propanol) an explosive mixture with air, with an explosion limit of 2.5% to 8.7% by volume.



PREPARATION OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is a major constituent of fusel oil, a by-product formed from certain amino acids when potatoes or grains are fermented to produce ethanol.
This is no longer a significant source of the material.

Propan-1-ol (n-propanol) is manufactured by catalytic hydrogenation of propionaldehyde.
The propionaldehyde is itself produced via the oxo process, by hydroformylation of ethylene using carbon monoxide and hydrogen in the presence of a catalyst such as cobalt octacarbonyl or a rhodium complex.

(1) H2C=CH2 + CO + H2 → CH3CH2CH=O
(2) CH3CH2CH=O + H2 → CH3CH2CH2OH
A traditional laboratory preparation of Propan-1-ol (n-propanol) involves treating 1-iodopropane with moist Ag2O.



HISTORY OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) was discovered in 1853 by Chancel, who obtained it by fractional distillation of fusel oil.



PREPARATION OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is manufactured by catalytic hydrogenation of propionaldehyde.
Propionaldehyde is produced via the oxo process by hydroformylation of ethylene using carbon monoxide and hydrogen in the presence of a catalyst such as cobalt octacarbonyl or a rhodium complex.

H2C=CH2 + CO + H2 → CH3CH2CH=O
CH3CH2CH=O + H2 → CH3CH2CH2OH
A traditional laboratory preparation of Propan-1-ol (n-propanol) involves treating n-propyl iodide with moist Ag2O.



CHEMICAL PROPERTIES OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) shows the normal reactions of a primary alcohol.
Thus Propan-1-ol (n-propanol) can be converted to alkyl halides; for example red phosphorus and iodine produce n-propyl iodide in 80% yield, while PCl3 with catalytic ZnCl2 gives n-propyl chloride.

Reaction with acetic acid in the presence of an H2SO4 catalyst under Fischer esterification conditions gives propyl acetate, while refluxing Propan-1-ol (n-propanol) overnight with formic acid alone can produce propyl formate in 65% yield.

Oxidation of Propan-1-ol (n-propanol) with Na2Cr2O7 and H2SO4 gives a 36% yield of propionaldehyde, and therefore for this type of reaction higher yielding methods using PCC or the Swern oxidation are recommended.
Oxidation with chromic acid yields propionic acid.



PREPARATION METHOD OF PROPAN-1-OL (n-PROPANOL):
propionaldehyde is synthesized from ethylene by carbonyl, and then Propan-1-ol (n-propanol) is obtained by hydrogenation.
Alternatively, Propan-1-ol (n-propanol) can be directly formed from ethylene and water using metal carbonyl compounds as catalysts.
Propan-1-ol (n-propanol) can also be prepared by liquid phase oxidation using propane or butane as a raw material.



CHEMICAL STRUCTURE OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is miscible in water and freely miscible with all common solvents such as glycols, ketones, alcohols, aldehydes, ethers and aliphatic hydrocarbons.
Propan-1-ol (n-propanol) is primarily used as a solvent in the manufacturing of pharmaceuticals, cosmetics, coatings and as a chemical intermediate.



HOW IS PROPAN-1-OL (n-PROPANOL) PRODUCED?
Normal Propan-1-ol (n-propanol) is manufactured by a catalytic hydrogenation of propionaldehyde.
The propionaldehyde is itself produced via the oxo process, by hydroformylation of ethylene using carbon monoxide and hydrogen in the presence of a catalyst such as cobalt octacarbonyl or a rhodium complex.

Hydrogenation is the process of adding pairs of hydrogen atoms to unsaturated compounds, with the aim of saturating these compounds.
H2C=CH2 + CO + H2 → CH3CH2CH=O
CH3CH2CH=O + H2 → CH3CH2CH2OH



HANDLING, STORAGE AND DISTRIBUTION OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) has an NFPA health rating of 1.
Propan-1-ol (n-propanol) sits in the alcohol and polyol reactive groups.
Propan-1-ol (n-propanol) reacts with alkali metal, nitrides, oxoacids and carboxylic acids.

Propan-1-ol (n-propanol) is not reactive with strong oxidising agents.
Propan-1-ol (n-propanol) reacts the same way as primary alcohols.
Propan-1-ol (n-propanol) can be converted to alkyl halides (red phosphorus, iodine), acetic acid to give propyl acetate and chromic acids to give propionic acid.



STORAGE AND DISTRIBUTION OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is typically bulk stored within a petrochemical storage facility for regulation.
Storage is normally in a cool, dry and well ventilated facility away from oxidising agents.
Propan-1-ol (n-propanol) should be kept out of direct sunlight, heat, and open flames.
Propan-1-ol (n-propanol) can be stored in drummed containers such as iso tanks made of stainless steel, aluminium or carbon steel.



DIFFERENCE BETWEEN PROPAN-1-OL (n-PROPANOL) AND ISOPROPYL ALCOHOL:
Propyl alcohol, also known as n-propyl alcohol or Propan-1-ol (n-propanol), is one of two isomeric alcohols used in chemical processing as solvents and intermediates.

Isopropyl alcohol is the second isomer (2-propanol).
Position isomerism can be seen in n-propyl alcohol and isopropyl alcohol.
Constitutional isomers have the same carbon skeleton and functional groups, but the functional groups are in different places.

The OH group is present on the first C atom in n-propyl alcohol.
The OH group is present on the second C atom in isopropyl alcohol.
When heated with I2 and NaOH solution, isopropyl alcohol produces a yellow iodoform precipitate, while n-propyl does not.



PREPARATION OF PROPAN-1-OL (n-PROPANOL):
a clean production process for the hydrogenation of propionaldehyde to produce Propan-1-ol (n-propanol), comprising the following steps: a, when the crude Propan-1-ol (n-propanol) generated by the hydrogenation of propionaldehyde enters the distillation system, the stripping tower condenses and exchanges the three-phase azeotrope residue formed by the reaction by-product propyl propionate, water and Propan-1-ol (n-propanol), the gas phase material separated by the pervaporation membrane dehydration device is condensed to obtain wastewater A, which is mixed with the raw material propionaldehyde and enters the system again, the condensed residual gas is evacuated by a vacuum pump;
The liquid phase material separated by the pervaporation membrane dehydration unit is sent to rectification to separate Propan-1-ol (n-propanol) and propyl propionate in the liquid phase material.



CONTENT ANALYSIS OF PROPAN-1-OL (n-PROPANOL):
the content of Propan-1-ol (n-propanol) and volatile impurities was determined by gas chromatography (GT-10-4) using a polar column.



PURIFICATION METHOD OF PROPAN-1-OL (n-PROPANOL):
a chromatographic pure Propan-1-ol (n-propanol) preparation method, the specific preparation steps are as follows:(1) take 50g shell type activated carbon, after drying at 150 ° C for 8 hours, put it in a desiccator for cooling;(2) take 1000ml of analytical pure Propan-1-ol (n-propanol) into an extraction bottle, add 50g step (1) after the pre-treated activated carbon is shaken for 30 minutes, it is placed for 10 hours, the activated carbon is filtered out, and the Propan-1-ol (n-propanol) is put into a 1000ml three-mouth distillation bottle; (3) after the rectification equipment is installed as required, the step (2) after further rectification of medium-Propan-1-ol (n-propanol), the reflux ratio was adjusted to 2:30, and 96.5-97.5 fractions were collected to obtain chromatographically pure Propan-1-ol (n-propanol), which was sampled and analyzed.
Inspection was conducted according to Q/12HB3730-2010 standard, and the yield of the finished product was about 88%.



REACTIVITY PROFILE OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) reacts with oxoacids and carboxylic acids to form esters plus water.
Propan-1-ol (n-propanol) is converted by oxidizing agents to propanal or propionic acid.
Propan-1-ol (n-propanol) may initiate the polymerization of isocyanates and epoxides.
Propan-1-ol (n-propanol) is incompatible with strong oxidizing agents.



PROPERTIES OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) forms binary azeotropes with acetal, benzene, biacetyl,1-bromobutane, 2-bromobutane, n-butyl chloride, butyl formate, carbon tetrachloride, chlorobenzene, 1-chlorobutane, 2-chlorobutane, 1-chloro-3-methylbutane, 1-chloro-2-methylpropane, diethoxymethane, dioxane, di-n-propyl ether, ethyl propionate, ethyl sulfide, ethylene chloride, fluorobenzene, n-hexane, 1-iodobutane, 2-iodobutane, 1-iodo-2-methylpropane, isobutyl formate, isobutyronitrile, methyl acrylate, 3-methyl-2-butanol, methyl butyrate, methyl isobutyrate, 2-pentanone, 3-pentanone, alpha-pinene, propyl acetate, n-propyl bromide, propyl formate, toluene, water.

Propan-1-ol (n-propanol) forms ternary azeotropes with water, acetaldehyde dipropylacetal; water, benzene; water, carbon tetrachloride; water, 1,3-cyclohexadiene; water, cyclohexane; water, cyclohexene; water, dipropoxymethane; water, ethoxypropoxymethane; water, 3-iodopropene; water, nitromethane; water, 3-pentanone; water, propyl acetate; water, propyl chloroacetate; water, propyl ether; water, propyl formate; water, trichloroethylene



PHYSICAL and CHEMICAL PROPERTIES of PROPAN-1-OL (n-PROPANOL):
Chemical formula: C3H8O
Molar mass: 60.096 g·mol−1
Appearance: Colorless liquid
Odor: mild, alcohol-like
Density: 0.803 g/mL
Melting point: −126 °C; −195 °F; 147 K
Boiling point: 97 to 98 °C; 206 to 208 °F; 370 to 371 K
Solubility in water: miscible
log P: 0.329
Vapor pressure: 1.99 kPa (at 20 °C)
Acidity (pKa): 16

Basicity (pKb): −2
Magnetic susceptibility (χ): −45.176·10−6 cm3/mol
Refractive index (nD): 1.387
Viscosity: 1.959 mPa·s (at 25 °C)
Dipole moment: 1.68 D
Heat capacity (C): 143.96 J/(K·mol)
Std molar entropy (S⦵298): 192.8 J/(K·mol)
Std enthalpy of formation (ΔfH⦵298): −302.79…−302.29 kJ/mol
Std enthalpy of combustion (ΔcH⦵298): −2.02156…−2.02106 MJ/mol
Molecular Weight: 60.10 g/mol
XLogP3: 0.3
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 1

Exact Mass: 60.057514874 g/mol
Monoisotopic Mass: 60.057514874 g/mol
Topological Polar Surface Area: 20.2Ų
Heavy Atom Count: 4
Formal Charge: 0
Complexity: 7.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical and physical properties of n-propanol:
Molecular Formula: CH3CH2CH2OH / n-PrOH
Synonyms: 1-propanol, n-propanol alcohol, propan-1-ol,
propyl alcohol, n-PrOH, 1-hydroxypropane, propionic alcohol

Cas Number: 71-23-8
Molecular Mass: 60.096 g/mol-1
Exact Mass: 60.057515 g/mol
Flashpoint: 77 °F / 22 °C
Boiling Point: 207 °F (at 760 mm Hg) / 97.2 °C
Melting Point: -195 °F / -126 °C
Vapour Pressure: 1.99 kPa (at 20 °C)
Water Solubility: miscible
Density: 0.803 g/mL
Log P: 0.329
Physical state: clear, liquid
Color: colorless
Odor: alcohol-like
Melting point/freezing point:
Melting point/range: -127 °C - lit.
Initial boiling point and boiling range: 97 °C - lit.
Flammability (solid, gas): No data available

Upper/lower flammability or explosive limits:
Upper explosion limit: 13,7 %(V)
Lower explosion limit: 2,1 %(V)
Flash point: 22 °C - closed cup
Autoignition temperature: 400 °C at 1.013,25 hPa
Decomposition temperature: No data available
pH: 8,5 at 200 g/l at 20 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 2,21 mPa.s at 20 °C
Water solubility: at 20 °C completely miscible
Partition coefficient: n-octanol/water:
log Pow: 0,2 at 25 °C - Bioaccumulation is not expected.
Vapor pressure: 19,3 hPa at 20 °C
Density: 0,804 g/cm3 at 25 °C - lit.

Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Surface tension: 23,45 mN/m at 20 °C
Relative vapor density: 2,07 - (Air = 1.0)
Boiling point: 96.5 - 98 °C (1013 hPa)
Density: 0.8 g/cm3 (20 °C)
Explosion limit: 2.1 - 19.2 %(V)
Flash point: 22 °C
Ignition temperature: 360 °C
Melting Point: -127 °C
pH value: 8.5 (200 g/l, H₂O, 20 °C)
Vapor pressure: 19.3 hPa (20 °C)

pH: 7
Melting Point: -127°C
Color: Colorless
Formula Weight:60.1g/mol
Boiling Point: 97°C
Physical Form: Liquid
Vapor Pressure: 25mbar at 20°C
Viscosity: 2.2 mPaS at 20°C
CAS: 71-23-8
EINECS: 200-746-9
InChI: InChI=1/C3H8O/c1-2-3-4/h4H,2-3H2,1H3
Molecular Formula: C3H8O
Molar Mass: 60.1
Density: 0.804 g/mL at 25 °C(lit.)

Melting Point: -127°C(lit.)
Boling Point: 97°C(lit.)
Flash Point: 59°F
JECFA Number: 82
Water Solubility: soluble
Solubility: H2O: passes test
Vapor Presure: 10 mm Hg ( 147 °C)
Vapor Density: 2.1 (vs air)
Appearance: Liquid
Color: <10(APHA)
Odor: Resembles that of ethyl alcohol.
Maximum wavelength(λmax):
['λ: 220 nm Amax: ≤0.40', , 'λ: 240 nm Amax: ≤0.071', 'λ: 275 nm Amax: ≤0.0044']
Merck: 14,7842
BRN: 1098242
pKa: >14 (Schwarzenbach et al., 1993)

PH: 7 (200g/l, H2O, 20℃)
Storage Condition: Store at +5°C to +30°C.
Stability: Stable.
Molecular Weight:60.095
Exact Mass:60.0575
EC Number:200-746-9
UNII:96F264O9SV
ICSC Number:0553
NSC Number:30300
UN Number:1274
DSSTox ID:DTXSID2021739
Color/Form:Colorless liquid.
HScode:2905121000
PSA:20.23
XLogP3:0.3887
Appearance:colourless liquid
Density:0.8

Melting Point:-127ºC
Boiling Point:97ºC
Flash Point:15ºC
Refractive Index:1.384-1.386
Water Solubility:soluble
Storage Conditions:Store at RT.
Vapor Pressure:10 mm Hg ( 147 °C)
Vapor Density:2.1 (vs air)
Odor:Similar to ethanol
Odor perception threshold: <0.07-100 mg/cu-m;
odor recognition threshold: 0.32-150 mg/cu m
Taste: CHARACTERISTIC RIPE, FRUITY FLAVOR
OH:5.53e-12 cm3/molecule*sec
Henrys Law Constant:7.41e-06 atm-m3/mole
Henry's Law constant = 7.41X10-6 atm-cu m/mol @ 25 °C

Dissociation Constants:
pKa = 16.10
Heat of fusion: 20.66 cal/g
Heat of solution: (est) -9 BTU/lb= -5 cal/g= -0.2X10+5 J/kg
Reid Vapor Pressure: 0.87 psia
Liquid heat capacity= 0.566 BTU/lb-F @ 70 °F
Ideal gas heat capacity= 0.345 BTU/lb-F @ 75 °C
Water Solubility: 391 g/L
logP: 0.21
logP: 0.36
logS: 0.81
pKa (Strongest Acidic): 16.85
pKa (Strongest Basic): -2
Physiological Charge: 0
Hydrogen Acceptor Count: 1

Hydrogen Donor Count: 1
Polar Surface Area: 20.23 Ų
Rotatable Bond Count: 1
Refractivity: 17.53 m³·mol⁻¹
Polarizability: 7.23 ų
Number of Rings: 0
Bioavailability: Yes
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: Yes
MDDR-like Rule: No
Chemical Formula: C3H8O
IUPAC name: propan-1-ol
InChI Identifier: InChI=1S/C3H8O/c1-2-3-4/h4H,2-3H2,1H3
InChI Key: BDERNNFJNOPAEC-UHFFFAOYSA-N
Isomeric SMILES: CCCO
Average Molecular Weight: 60.095
Monoisotopic Molecular Weight: 60.057514878



FIRST AID MEASURES of PROPAN-1-OL (n-PROPANOL):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of PROPAN-1-OL (n-PROPANOL):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of PROPAN-1-OL (n-PROPANOL):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of PROPAN-1-OL (n-PROPANOL):
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 120 min
*Body Protection:
Flame retardant antistatic protective clothing.
*Respiratory protection:
Recommended Filter type: Filter A (acc. to DIN 3181)
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of PROPAN-1-OL (n-PROPANOL):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Advice on protection against fire and explosion:
Take precautionary measures against static discharge.
*Hygiene measures:
Change contaminated clothing.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
Storage conditions
Keep container tightly closed in a dry and well-ventilated place.
Keep away from heat and sources of ignition.



STABILITY and REACTIVITY of PROPAN-1-OL (n-PROPANOL):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



PROPAN-2-OL
Propan-2-ol Isopropyl Alcohol Propan-2-ol (izopropil alkol, Isopropanol, IPA) is an organic compound, an isomer of n-propanol, aliased dimethylmethanol, 2-propanol. Propan-2-ol(izopropil alkol, Isopropanol, IPA) is a colorless, transparent liquid with a scent like a mixture of ethanol and acetone. Soluble in water, also soluble in most organic solvents such as alcohol, ether, benzene, chloroform, etc. Propan-2-ol(izopropil alkol, Isopropanol, IPA) has a wide range of uses as an organic raw material and solvent. 1)As a chemical raw material, it can produce acetone, hydrogen peroxide, methyl isobutyl ketone, diisobutyl ketone, isopropylamine, diisopropyl ether, isopropyl chloride, and fatty acid isopropyl ester and chloro fatty acid isopropyl ester. 2)In the fine chemical industry, it can be used to produce isopropyl nitrate, isopropyl xanthate, triisopropyl phosphite, aluminum isopropoxide, pharmaceuticals and pesticides, etc. It can also be used to produce diisopropanone, isopropyl acetate and Thymol and gasoline additives. 3)Propan-2-ol(izopropil alkol, Isopropanol, IPA) Can be used to produce coatings, inks, extractants, aerosols, etc. 4) In the electronics industry, Propan-2-ol(izopropil alkol, Isopropanol, IPA) can be used as a cleaning and degreasing agent. 5) In the oil and fat industry, the extractant of cottonseed oil can also be used for degreasing of animal-derived tissue membranes. Propan-2-ol(izopropil alkol, Isopropanol, IPA) (IUPAC name propan-2-ol; commonly called Propan-2-olor 2-propanol) is a colorless, flammable chemical compound (chemical formula CH3CHOHCH3) with a strong odor.[8] As an isopropyl group linked to a hydroxyl group, it is the simplest example of a secondary alcohol, where the alcohol carbon atom is attached to two other carbon atoms. It is a structural isomer of 1-propanol and ethyl methyl ether. Propan-2-ol(izopropil alkol, Isopropanol, IPA) is used in the manufacture of a wide variety of industrial and household chemicals and is a common ingredient in chemicals such as antiseptics, disinfectants, and detergents. Names of Propan-2-ol(izopropil alkol, Isopropanol, IPA) Propan-2-ol(izopropil alkol, Isopropanol, IPA) Propan-2-ol(izopropil alkol, Isopropanol, IPA) is also known as 2-propanol, sec-propyl alcohol, IPA, or isopropanol. IUPAC considers Propan-2-olan incorrect name as the hydrocarbon isopropane does not exist. Properties of Propan-2-ol(izopropil alkol, Isopropanol, IPA) Propan-2-ol(izopropil alkol, Isopropanol, IPA) is miscible in water, ethanol, ether, and chloroform. It dissolves ethyl cellulose, polyvinyl butyral, many oils, alkaloids, gums and natural resins.[9] Unlike ethanol or methanol, Propan-2-ol(izopropil alkol, Isopropanol, IPA) is not miscible with salt solutions and can be separated from aqueous solutions by adding a salt such as sodium chloride. The process is colloquially called salting out, and causes concentrated Propan-2-ol(izopropil alkol, Isopropanol, IPA) to separate into a distinct layer. Propan-2-ol(izopropil alkol, Isopropanol, IPA) forms an azeotrope with water, which gives a boiling point of 80.37 °C (176.67 °F) and a composition of 87.7 wt% (91 vol%) Propan-2-ol(izopropil alkol, Isopropanol, IPA). Water-Propan-2-ol(izopropil alkol, Isopropanol, IPA) mixtures have depressed melting points.[10] It has a slightly bitter taste, and is not safe to drink. Propan-2-ol(izopropil alkol, Isopropanol, IPA) becomes increasingly viscous with decreasing temperature and freezes at -89 °C (-128 °F). Propan-2-ol(izopropil alkol, Isopropanol, IPA) has a maximal absorbance at 205 nm in an ultraviolet-visible spectrum. Reactions of Propan-2-ol(izopropil alkol, Isopropanol, IPA) Propan-2-ol(izopropil alkol, Isopropanol, IPA) can be oxidized to acetone, which is the corresponding ketone. This can be achieved using oxidizing agents such as chromic acid, or by dehydrogenation of Propan-2-ol(izopropil alkol, Isopropanol, IPA) over a heated copper catalyst: (CH3)2CHOH → (CH3)2CO + H2 Propan-2-ol(izopropil alkol, Isopropanol, IPA) is often used as both solvent and hydride source in the Meerwein-Ponndorf-Verley reduction and other transfer hydrogenation reactions. Propan-2-ol(izopropil alkol, Isopropanol, IPA) may be converted to 2-bromopropane using phosphorus tribromide, or dehydrated to propene by heating with sulfuric acid. Like most alcohols, Propan-2-ol(izopropil alkol, Isopropanol, IPA) reacts with active metals such as potassium to form alkoxides that can be called isopropoxides. The reaction with aluminium (initiated by a trace of mercury) is used to prepare the catalyst aluminium isopropoxide.[14] History of Propan-2-ol(izopropil alkol, Isopropanol, IPA) In 1920, Standard Oil first produced Propan-2-ol(izopropil alkol, Isopropanol, IPA) by hydrating propene. Its major use at the time was not rubbing alcohol but for oxidation to acetone, whose first major use was in World War I for the preparation of cordite, a smokeless, low explosive propellant. Production of Propan-2-ol(izopropil alkol, Isopropanol, IPA) In 1994, 1.5 million tonnes of Propan-2-ol(izopropil alkol, Isopropanol, IPA) were produced in the United States, Europe, and Japan.[16] It is primarily produced by combining water and propene in a hydration reaction or by hydrogenating acetone. There are two routes for the hydration process and both processes require that the Propan-2-ol(izopropil alkol, Isopropanol, IPA) be separated from water and other by-products by distillation. Propan-2-ol(izopropil alkol, Isopropanol, IPA) and water form an azeotrope, and simple distillation gives a material that is 87.9% by weight Propan-2-ol(izopropil alkol, Isopropanol, IPA) and 12.1% by weight water.[18] Pure (anhydrous) Propan-2-ol(izopropil alkol, Isopropanol, IPA) is made by azeotropic distillation of the wet Propan-2-ol(izopropil alkol, Isopropanol, IPA) using either diisopropyl ether or cyclohexane as azeotroping agents.[16] Biological of Propan-2-ol(izopropil alkol, Isopropanol, IPA) Small amounts of Propan-2-ol(izopropil alkol, Isopropanol, IPA) are produced in the body in diabetic ketoacidosis.[19] Indirect hydration of Propan-2-ol(izopropil alkol, Isopropanol, IPA) Indirect hydration reacts propene with sulfuric acid to form a mixture of sulfate esters. This process can use low-quality propene, and is predominant in the USA. These processes give primarily Propan-2-ol(izopropil alkol, Isopropanol, IPA) rather than 1-propanol, because adding water or sulfuric acid to propene follows Markovnikov's rule. Subsequent hydrolysis of these esters by steam produces Propan-2-ol(izopropil alkol, Isopropanol, IPA), by distillation. Diisopropyl ether is a significant by-product of this process; it is recycled back to the process and hydrolyzed to give the desired product. CH3CH=CH2 + H2O H2SO4⟶ (CH3)2CHOH Direct hydration of Propan-2-ol(izopropil alkol, Isopropanol, IPA) See also: Heteropoly acid Direct hydration reacts propene and water, either in gas or liquid phase, at high pressures in the presence of solid or supported acidic catalysts. This type of process usually requires higher-purity propylene (> 90%).[16] Direct hydration is more commonly used in Europe. Hydrogenation of acetone Propan-2-ol(izopropil alkol, Isopropanol, IPA) may be prepared via the hydrogenation of acetone, however this approach involves an extra step compared to the above methods, as acetone is itself normally prepared from propene via the cumene process.[16] It may remain economical depending on the value of the products. A known issue is the formation of MIBK and other self-condensation products. Raney nickel was one of the original industrial catalysts, modern catalysts are often supported bimetallic materials. This is an efficient process and easy Uses of Propan-2-ol(izopropil alkol, Isopropanol, IPA) One of the small scale uses of Propan-2-olis in cloud chambers. Propan-2-olhas ideal physical and chemical properties to form a supersaturated layer of vapor which can be condensed by particles of radiation. In 1990, 45,000 metric tonnes of Propan-2-ol(izopropil alkol, Isopropanol, IPA) were used in the United States, mostly as a solvent for coatings or for industrial processes. In that year, 5400 metric tonnes were used for household purposes and in personal care products. Propan-2-ol(izopropil alkol, Isopropanol, IPA) is popular in particular for pharmaceutical applications,[16] due to its low toxicity. Some Propan-2-ol(izopropil alkol, Isopropanol, IPA) is used as a chemical intermediate. Propan-2-ol(izopropil alkol, Isopropanol, IPA) may be converted to acetone, but the cumene process is more significant. [16] Solvent of Propan-2-ol(izopropil alkol, Isopropanol, IPA) Propan-2-ol(izopropil alkol, Isopropanol, IPA) dissolves a wide range of non-polar compounds. It also evaporates quickly, leaves nearly zero oil traces, compared to ethanol, and is relatively non-toxic, compared to alternative solvents. Thus, it is used widely as a solvent and as a cleaning fluid, especially for dissolving oils. Together with ethanol, n-butanol, and methanol, it belongs to the group of alcohol solvents, about 6.4 million tonnes of which were used worldwide in 2011.[20] Propan-2-ol(izopropil alkol, Isopropanol, IPA) is commonly used for cleaning eyeglasses, electrical contacts, audio or video tape heads, DVD and other optical disc lenses, removing thermal paste from heatsinks on CPUs and other IC packages, etc. Intermediate Propan-2-ol(izopropil alkol, Isopropanol, IPA) is esterified to give isopropyl acetate, another solvent. It reacts with carbon disulfide and sodium hydroxide to give sodium isopropylxanthate, a herbicide and an ore flotation reagent.[21] Propan-2-ol(izopropil alkol, Isopropanol, IPA) reacts with titanium tetrachloride and aluminium metal to give titanium and aluminium isopropoxides, respectively, the former a catalyst, and the latter a chemical reagent.[16] This compound may serve as a chemical reagent in itself, by acting as a dihydrogen donor in transfer hydrogenation. Medical of Propan-2-ol(izopropil alkol, Isopropanol, IPA) Rubbing alcohol, hand sanitizer, and disinfecting pads typically contain a 60-70% solution of Propan-2-ol(izopropil alkol, Isopropanol, IPA) or ethanol in water. Water is required to open up membrane pores of bacteria, which acts as a gateway for Propan-2-ol(izopropil alkol, Isopropanol, IPA). A 75% v/v solution in water may be used as a hand sanitizer.[22] Propan-2-ol(izopropil alkol, Isopropanol, IPA) is used as a water-drying aid for the prevention of otitis externa, better known as swimmer's ear.[23] Early uses as an anesthetic Although Propan-2-ol(izopropil alkol, Isopropanol, IPA) can be used for anesthesia, its many negative attributes or drawbacks prohibit this use. Propan-2-ol(izopropil alkol, Isopropanol, IPA) can also be used similarly to ether as a solvent[24] or as an anesthetic by inhaling the fumes or orally. Early uses included using the solvent as general anesthetic for small mammals[25] and rodents by scientists and some veterinarians. However, it was soon discontinued, as many complications arose, including respiratory irritation, internal bleeding, and visual and hearing problems. In rare cases, respiratory failure leading to death in animals was observed. Automotive Propan-2-ol(izopropil alkol, Isopropanol, IPA) is a major ingredient in "gas dryer" fuel additives. In significant quantities, water is a problem in fuel tanks, as it separates from gasoline and can freeze in the supply lines at low temperatures. Alcohol does not remove water from gasoline, but the alcohol solubilizes water in gasoline. Once soluble, water does not pose the same risk as insoluble water, as it no longer accumulates in the supply lines and freezes but is consumed with the fuel itself. Propan-2-ol(izopropil alkol, Isopropanol, IPA) is often sold in aerosol cans as a windshield or door lock deicer. Propan-2-ol(izopropil alkol, Isopropanol, IPA) is also used to remove brake fluid traces from hydraulic braking systems, so that the brake fluid (usually DOT 3, DOT 4, or mineral oil) does not contaminate the brake pads and cause poor braking. Mixtures of Propan-2-ol(izopropil alkol, Isopropanol, IPA) and water are also commonly used in homemade windshield washer fluid. Laboratory As a biological specimen preservative, Propan-2-ol(izopropil alkol, Isopropanol, IPA) provides a comparatively non-toxic alternative to formaldehyde and other synthetic preservatives. Propan-2-ol(izopropil alkol, Isopropanol, IPA) solutions of 70-99% are used to preserve specimens. Propan-2-ol(izopropil alkol, Isopropanol, IPA) is often used in DNA extraction. A lab worker adds it to a DNA solution to precipitate the DNA, which then forms a pellet after centrifugation. This is possible because DNA is insoluble in Propan-2-ol(izopropil alkol, Isopropanol, IPA). Safety of Propan-2-ol(izopropil alkol, Isopropanol, IPA) Propan-2-ol(izopropil alkol, Isopropanol, IPA) vapor is denser than air and is flammable, with a flammability range of between 2 and 12.7% in air. It should be kept away from heat and open flame.[26] Distillation of Propan-2-ol(izopropil alkol, Isopropanol, IPA) over magnesium has been reported to form peroxides, which may explode upon concentration. Propan-2-ol(izopropil alkol, Isopropanol, IPA) is a skin irritant. Wearing protective gloves is recommended. Toxicology of Propan-2-ol(izopropil alkol, Isopropanol, IPA) Propan-2-ol(izopropil alkol, Isopropanol, IPA) and its metabolite, acetone, act as central nervous system (CNS) depressants.[31] Poisoning can occur from ingestion, inhalation, or skin absorption. Symptoms of Propan-2-ol(izopropil alkol, Isopropanol, IPA) poisoning include flushing, headache, dizziness, CNS depression, nausea, vomiting, anesthesia, hypothermia, low blood pressure, shock, respiratory depression, and coma.[31] Overdoses may cause a fruity odor on the breath as a result of its metabolism to acetone.[32] Propan-2-ol(izopropil alkol, Isopropanol, IPA) does not cause an anion gap acidosis but it produces an osmolal gap between the calculated and measured osmolalities of serum, as do the other alcohols.[31] Propan-2-ol(izopropil alkol, Isopropanol, IPA) is oxidized to form acetone by alcohol dehydrogenase in the liver,[31] and has a biological half-life in humans between 2.5 and 8.0 hours.[31] Unlike methanol or ethylene glycol poisoning, the metabolites of Propan-2-ol(izopropil alkol, Isopropanol, IPA) are considerably less toxic, and treatment is largely supportive. Furthermore, there is no indication for the use of fomepizole, an alcohol dehydrogenase inhibitor, unless co-ingestion with methanol or ethylene glycol is suspected. In forensic pathology, people who have died as a result of diabetic ketoacidosis usually have blood concentrations of Propan-2-ol(izopropil alkol, Isopropanol, IPA) of tens of mg/dL, while those by fatal Propan-2-ol(izopropil alkol, Isopropanol, IPA) ingestion usually have blood concentrations of hundreds of mg/dL. Propan-2-ol(izopropil alkol, Isopropanol, IPA) will attack some forms of plastics, rubber, and coatings. Propan-2-ol(izopropil alkol, Isopropanol, IPA) is an isomer of propyl alcohol with antibacterial properties. Although the exact mechanism of isopropanol's disinfecting action is not known, it might kill cells by denaturing cell proteins and DNA, interfering with cellular metabolism, and dissolving cell lipo-protein membranes. Propan-2-olis used in soaps and lotions as an antiseptic. Any clothing which becomes wet with liquid Propan-2-ol(izopropil alkol, Isopropanol, IPA) should be removed immediately and not reworn until the Propan-2-ol(izopropil alkol, Isopropanol, IPA) is removed from the clothing. Clothing should then be placed in closed containers for storage until it can be discarded or until provision can be made for the removal of Propan-2-ol(izopropil alkol, Isopropanol, IPA) from the clothing. If the clothing is to be laundered or otherwise cleaned to remove the Propan-2-ol(izopropil alkol, Isopropanol, IPA), the person performing the operation should be informed of Propan-2-ol(izopropil alkol, Isopropanol, IPA)'s hazardous properties. When a stream of hydrogen entrained Propan-2-ol(izopropil alkol, Isopropanol, IPA) vapors and palladium particles, the mixture caught fire on exposure to air. Solutions of 90% nitroform in 10% Propan-2-ol(izopropil alkol, Isopropanol, IPA) in polyethylene bottles exploded. The reaction between Propan-2-ol(izopropil alkol, Isopropanol, IPA) and phosgene forms isopropyl chloroformate and hydrogen chloride. In the presence of iron salts thermal decomposition can occur, which in some cases can become explosive. Mixing oleum and Propan-2-ol(izopropil alkol, Isopropanol, IPA) in a closed container caused the temperature and pressure to increase. Propan-2-ol(izopropil alkol, Isopropanol, IPA) (without residue) may be used in inks for marking food supplements in tablet form, gum, and confectionery. Propan-2-ol(izopropil alkol, Isopropanol, IPA) may be present in the following foods under the conditions specified: (a) In spice oleoresins as a residue from the extraction of spice, at a level not to exceed 50 parts per million. (b) In lemon oil as a residue in production of the oil, at a level not to exceed 6 parts per million. (c) In hops extract as a residue from the extraction of hops at a level not to exceed 2.0 percent by weight: Provided, that, (1) The hops extract is added to the wort before or during cooking in the manufacture of beer. (2) The label of the hops extract specifies the presence of the Propan-2-ol(izopropil alkol, Isopropanol, IPA) and provides for the use of the hops extract only as prescribed by paragraph (c)(1) of this section. WORKERS IN AN Propan-2-ol(izopropil alkol, Isopropanol, IPA) PACKAGING PLANT BECAME ILL AFTER ACCIDENTAL EXPOSURE TO CARBON TETRACHLORIDE. Propan-2-ol(izopropil alkol, Isopropanol, IPA) POTENTIATION OF CARBON TETRACHLORIDE TOXICITY HAS BEEN SHOWN PREVIOUSLY ONLY IN RATS. ACETONE, A PRODUCT OF Propan-2-ol(izopropil alkol, Isopropanol, IPA) METABOLISM, IS A MAJOR POTENTIATOR OF CARBON TETRACHLORIDE TOXICITY. IDENTIFICATION: Propan-2-ol(izopropil alkol, Isopropanol, IPA) is an aliphatic alcohol hydrocarbon. It is prepared from propylene, which is obtained in the cracking of petroleum or by the reduction of acetone. It is a colorless liquid which is soluble in water, alcohol, ether, acetone, benzene and chloroform. It is insoluble in salt solutions. It has a slight odor resembling a mixture of ethanol and acetone and has a slight bitter taste. It is used in antifreeze, industrial solvent, solvent for gums, shellac, essential oils, in quick drying oils, creosote and resins; extraction of alkaloids; in quick drying inks; in denaturing ethyl alcohol; in body rubs, hand lotions, after shave lotions, cosmetics and pharmaceuticals; in manufacture of acetone, glycerol, isopropyl acetate; antiseptic; rubefacient ; and pharmaceutical aid. HUMAN EXPOSURE: Toxic effects include central nervous depression, liver, kidney, cardiovascular depression and brain damage. It can cause drowsiness, ataxia, stupor, coma and respiratory depression, irritation of mucous membranes and eyes, gastritis, gastric hemorrhage, vomiting, pancreatitis, cold clammy skin, hypothermia, miosis, tachycardia, slow and noisy respiration. High risk of circumstances of poisoning: Accidental ingestion of rubbing alcohols/toiletries by children. There is a potential exposure from dermal and inhalation exposure in children during Propan-2-ol(izopropil alkol, Isopropanol, IPA) sponging for control of fever. Intentional ingestion for alcoholic effect or in suicide attempts. Occupational or accidental exposure to liquid or its vapor in industrial applications. Individuals exposed to Propan-2-ol(izopropil alkol, Isopropanol, IPA) include the following: workers in the pharmaceutical industry, cosmetic industry, chemical industry, petroleum workers, laboratory workers, printers, painters and carpenters and cabinet makers. There is little absorption through intact skin. Propan-2-ol(izopropil alkol, Isopropanol, IPA) is a potent eye and skin irritant. 80% of an oral dose is absorbed within 30 minutes. Absorption is complete within 2 hours although this may be delayed in a large overdose. Alveolar concentration is correlated to the environmental concentration at any given time. Propan-2-ol(izopropil alkol, Isopropanol, IPA) is absorbed through intact skin on prolonged exposure. Propan-2-ol(izopropil alkol, Isopropanol, IPA) distributes in body water with an apparent volume of distribution of 0.6-0.7 L/kg. 20-50% of an absorbed dose is excreted unchanged. Most Propan-2-ol(izopropil alkol, Isopropanol, IPA) is oxidized in the liver by alcohol dehydrogenase to acetone, formate and finally carbon dioxide. Acetone is slowly eliminated by the lung (40%) or kidney. Clinically insignificant excretion occurs into the stomach and saliva. Related keto acids are not produced in sufficient quantities to cause a severe metabolic acidosis. Inebriation, peripheral vasodilation has occurred. In children, hypoglycemia is particularly severe when poisoning following fasting, exercise or chronic malnutrition Lactic acidosis may occur in patients with severe liver disease, pancreatitis or receiving biguanide therapy or as a result of the hypovolemia which frequently accompanies severe intoxication. ANIMAL STUDIES: Propan-2-ol(izopropil alkol, Isopropanol, IPA) most closely follows first order kinetics, with a half life of 2.5 to 3.2 hours. The elimination half life of the active metabolite acetone is significantly prolonged to about 5 hours in rats. In rat hepatocytes the following has been observed: marked depletion of glutathione, increased malondialdehyde production, decreased protein sulfhydryls content and leakage of lactic dehydrogenase with loss of membrane activity. A complete history and physical examination should be performed to detect pre existing conditions that might place the employee at increased risk, and to establish a baseline for future health monitoring. Examination of the skin, liver, kidneys, and respiratory system should be stressed. Skin disease: Propan-2-ol(izopropil alkol, Isopropanol, IPA) is a defatting agent and can cause dermatitis on prolonged exposure. Persons with pre existing skin disorders may be more susceptible to the effects of this agent. Liver disease: Although Propan-2-ol(izopropil alkol, Isopropanol, IPA) is not known as a liver toxin in humans, the importance of this organ in the biotransformation and detoxification of foreign substances should be considered before exposing persons with impaired liver function. Kidney disease: Although Propan-2-ol(izopropil alkol, Isopropanol, IPA) is not known as a kidney toxin in humans, the importance of this organ in the elimination of toxic substances justifies special consideration in those with impaired renal function. Chronic respiratory disease: In persons with impaired pulmonary function, especially those with obstructive airway diseases, the breathing of Propan-2-ol(izopropil alkol, Isopropanol, IPA) might cause exacerbation of symptoms due to its irritant properties. Periodic Medical Examination: The aforementioned medical examinations should be repeated on an annual basis. The assessment of Propan-2-ol(izopropil alkol, Isopropanol, IPA) exposure can be accomplished through measurement of either Propan-2-ol(izopropil alkol, Isopropanol, IPA) or acetone. Propan-2-ol(izopropil alkol, Isopropanol, IPA) measurement has not been found to be a good assessment of low level exposure, due to its low sensitivity. However, measurement of acetone has been found to be a good indicator of Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) exposure for exposures as low as 70 ppm, and has been found to correlate well with air concentrations. Whole Blood Reference Ranges: Normal - none detected (Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA)); Exposed - BAT (sampling time is end of exposure or end of shift, measured as the metabolite, acetone), 50 mg/l; Toxic - Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) level associated with serious toxic symptoms is 150 mg/l. Serum or Plasma Reference Ranges: Normal - none detected (Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA)); Exposed - not established; and Toxic - not established. Urine Reference Ranges: The assessment of Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) exposure can be accomplished through measurement of either Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) or acetone. However only acetone was found to be a useful test, due to its greater sensitivity and good correlation with air exposure levels. Normal - none detected (Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA)); Exposed - BAT (sampling time is end of exposure or end of shift, measured as the metabolite, acetone), 50 mg/l; Toxic - Not established. Persons with pre existing skin disorders may be more susceptible to the effects of this agent. ... In persons with impaired pulmonary function, especially those with obstructive airway diseases, the breathing of Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) might cause exacerbation of symptoms due to its irritant properties. Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA)'s production and use in the manufacture of acetone, glycerol, and isopropyl acetate and as a solvent for a variety of applications may result in its release to the environment through various waste streams. Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA)'s use in hydraulic fracturing fluids results in its direct release to the environment. Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) has been identified as a metabolic product of aerobic microorganisms, anaerobic microorganisms, fungi, and yeast. If released to air, a vapor pressure of 45.4 mm Hg at 25 °C indicates Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) will exist solely as a vapor in the ambient atmosphere. Vapor-phase Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 3.2 days. If released to soil, Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) is expected to have very high mobility based upon an estimated Koc of 1.5. Volatilization from moist soil surfaces is expected to be an important fate process based upon a Henry's Law constant of 8.10X10-6 atm-cu m/mole. Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) is expected to volatilize from dry soil surfaces based upon its vapor pressure. If released into water, Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) is not expected to adsorb to suspended solids and sediment based upon the estimated Koc. Volatilization from water surfaces is expected to be an important fate process based upon this compound's Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 86 hours and 29 days, respectively. An estimated BCF of 3 suggests the potential for bioconcentration in aquatic organisms is low. Hydrolysis is not expected to occur due to the lack of hydrolyzable functional groups. Biodegradation is expected to be an important fate process based on the results of microbial screening tests. Occupational exposure to Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) may occur through inhalation and dermal contact with this compound at workplaces where Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) is produced or used. Monitoring data indicate that the general population may be exposed to Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) via inhalation of ambient air, ingestion of food and drinking water, and dermal contact with this compound directly and from consumer products containing Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA). ANAEROBIC: Typical Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) removal efficiencies for an anaerobic lagoon treatment facility, with a retention time of 15 days, were 50% after loading with dilute waste, and 69 and 74% after loading with concentrated wastes(1). In closed bottle studies, Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) was completely degraded anaerobically by an acetate-enriched culture, derived from a seed of domestic sludge(1). The culture started to use cross-fed Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA), after 4 days, at a rate of 200 mg/L/day(1). In a mixed reactor with a 20-day retention time, seeded by the same culture, 56% removal was achieved in the 20 days following 70 days of acclimation to a final concentration of 10,000 mg/L(1). The avg percent removal of Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) in semi-pilot scale anaerobic lagoons was 50% in 7.5-10 days for dilute wastes with 60 ppm Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) and 69-74% in 20-40 days for concentrated wastes with 175 ppm Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA)(2). Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) was readily mineralized to methane and carbon dioxide under methanogenic conditions(3). The degradation rate of Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) under these conditions in fuel impacted river sediments and industrial/sewage impacted creek sediments was 2.4 ppm C/day (82% of expected methane recovery) and 3.0 ppm C/day (91% of expected methane recovery), respectively(3). The degradation rate of Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) in a sediment slurry from a shallow anoxic aquifer under methanogenic conditions was 7.6 ppm C/day (112% of theoretical methane recovery)(4). In anaerobic bioreactor studies using a granular sludge inocula, Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) (at 125 ppm initial concentration) degraded with 115.5% of theoretical methane production over a 21-day incubation period(5); acetone was identified as a metabolite(5). In laboratory anaerobic sludge reactor tests using liquid hen manure as inoculum, Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) was degraded 100% in a 13-day incubation period with lag period(6). The Henry's Law constant for Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) is 8.10X10-6 atm-cu m/mole at 25 °C(1). This Henry's Law constant indicates that Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) is expected to volatilize from water surfaces(2). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 86 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 29 days(SRC). Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA)'s Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) is expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 45.2 mm Hg at 25 °C(3). The volatilization of Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) from a runoff tank of an industrial wastewater treatment facility was measured; the volatilization rate of Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) ranged between 0.64-0.69 mg/sq m-min(4). The evaporation rate of a 1:1 Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA):water mixture from a shallow pool was 1.5 kg/sq-m per hour at a wind speed of 4.5 m/s and pool temperature of 20 °C and an ambient air temperature of 22 °C(5). Laboratory studies demonstrated that Isopropyl alcohol (izopropil alkol, isopropyl alcohol, IPA) will volatilize from water to air in the absence of wind(6).
PROPANEDIOIC ACID (MALONIC ACID)
Propanedioic acid (Malonic acid) is a dicarboxylic acid with structure CH2(COOH)2.
Propanedioic acid (Malonic acid) acts as a cross linker in the coating industry and surgical adhesive.
Propanedioic acid (Malonic acid) is soluble in cold water.


CAS Number: 141-82-2
EC Number: 205-503-0
MDL number: MFCD00002707
Linear Formula: CH2(COOH)2
Molecular Formula: C3H4O4 / COOHCH2COOH



Malonic acid, Carboxyacetic acid, Dicarboxymethane, Methanedicarboxylic acid, CH2(COOH)2, USAF EK-695, Kyselina malonova, Methanedicarbonic acid, NSC 8124 H2malo, HOOC-CH2-COOH, Malonic acid, MALONIC ACID, propanedioic acid, Propanedioic acid, PROPANEDIOIC ACID, MAAC, Daucic acid, CH2(COOH)2, Methane acid, Propandioic acid, Methanedicarbonic acid, METHANEDICARBOXYLIC ACID, MALONIC ACID, 99%MALONIC ACID, 99%MALONIC ACID, 99%MALONIC ACID, 99%, Malonsure, malonic acid, propanedioic acid, 141-82-2, Dicarboxymethane, Carboxyacetic acid, Methanedicarboxylic acid, malonate, Kyselina malonova, USAF EK-695, 1,3-Propanedioic acid, Dicarboxylate, Malonicacid, Dicarboxylic acid, NSC 8124, UNII-9KX7ZMG0MK, 9KX7ZMG0MK, AI3-15375, H2malo, EINECS 205-503-0, MFCD00002707, BRN 1751370, Methanedicarbonic acid, CHEBI:30794, Thallium malonate, HOOC-CH2-COOH, NSC-8124, Propane-1,3-dioic acid, alpha,omega-Dicarboxylic acid, DTXSID7021659, HSDB 8437, NSC8124, 4-02-00-01874 (Beilstein Handbook Reference), 1,3-Propanoic acid, PROPANEDIOLIC ACID, METAHNEDICARBOXYLIC ACID, 2fah, Malonic acid, 99%, Malonic acid (8CI), 1o4m, MLI, Malonate dicarboxylic acid, Malonic acid, 99.5%, Propanedioic acid (9CI), SCHEMBL336, WLN: QV1VQ, MALONIC ACID [MI], CH2(COOH)2, CHEMBL7942, MALONIC ACID [INCI], DTXCID401659, SCHEMBL1471092, BDBM14673, Propanedioic acid dithallium salt, Malonic acid, analytical standard, AMY11201, BCP05571, STR00614, Tox21_200534, AC8295, LMFA01170041, s3029, Malonic acid, ReagentPlus(R), 99%, AKOS000119034, CS-W019962, DB02175, PROPANEDIOIC ACID MALONIC ACID, NCGC00248681-01, NCGC00258088-01, BP-11453, CAS-141-82-2, SY001875, Malonic acid, SAJ first grade, >=99.0%, FT-0628127, FT-0628128, FT-0690260, FT-0693474, M0028, NS00013842, EN300-18457, Malonic acid, Vetec(TM) reagent grade, 98%, C00383, C02028, C04025, Q421972, J-521669, Z57965450, F1908-0177, Malonic acid, certified reference material, TraceCERT(R), 592A9849-68C3-4635-AA3D-CBC44965EA3A, Malonic acid, sublimed grade, >=99.95% trace metals basis, DICARBOXYLIC ACID C3; PROPANEDIOLIC ACID; METHANEDICARBOXYLIC ACID, InChI=1/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7, Malonic acid, anhydrous, free-flowing, Redi-Dri(TM), ReagentPlus(R), 99%, LML, Propanedioic acid, Methanedicarboxylic acid, H2Malo, HOOC-CH2-COOH, Propanedioic acid, Propanedioate, Malonate, alpha,Omega-dicarboxylic acid, Carboxyacetic acid, Dicarboxylate, Dicarboxylic acid, Dicarboxymethane, Kyselina malonova, Malonate dicarboxylic acid, Metahnedicarboxylic acid, Methanedicarbonic acid, Methanedicarboxylic acid, Propanedioic acid dithallium salt, Propanediolic acid, Thallium malonate, Malonic acid, 2-(14)C-labeled, Malonic acid, monocalcium salt, Malonic acid, 1,3-(14)C2-labeled, Malonic acid, diammonium salt, Malonic acid, disodium salt, Malonic acid, dithallium salt, Malonic acid, dipotassium salt, Malonic acid, disodium salt, 1-(14)C-labeled, Malonic acid, monosodium salt, Malonic acid, potassium salt, Malonic acid, sodium salt, Thallous malonate, Dithallium malonate, Monosodium malonate, Malonic acid, malonic acid, dicarboxymethane, carboxyacetic acid, methanedicarboxylic acid, kyselina malonova, usaf ek-695, dicarboxylate, dicarboxylic acid, kyselina malonova czech, propanediolic acid, Malonic acid, Carboxyacetic acid, Dicarboxymethane, Methanedicarboxylic acid, CH2(COOH)2, USAF EK-695, Kyselina malonova, Methanedicarbonic acid, NSC 8124, alpha,Omega-dicarboxylic acid, Carboxyacetic acid, Dicarboxylate, Dicarboxylic acid, Dicarboxymethane, H2Malo, HOOC-CH2-COOH, Kyselina malonova, Malonate, Malonate dicarboxylic acid, Malonic acid, 1,3-(14)C2-labeled, Malonic acid, 2-(14)C-labeled, Malonic acid, diammonium salt, Malonic acid, dipotassium salt, Malonic acid, disodium salt, Malonic acid, disodium salt, 1-(14)C-labeled, Malonic acid, dithallium salt, Malonic acid, monocalcium salt, Malonic acid, monosodium salt, Malonic acid, potassium salt, Malonic acid, sodium salt, Metahnedicarboxylic acid, Methanedicarbonic acid, Methanedicarboxylic acid, Propanedioate, Propanedioic acid, Propanedioic acid dithallium salt, Propanediolic acid, Thallium malonate, Thallous malonate, Dithallium malonate, Monosodium malonate, Malonic acid, Malonic Acid, Disodium Salt, 1 (14)C Labeled, Propanedioic Acid Dithallium Salt, Malonic Acid, 1,3 (14)C2 Labeled, Malonic Acid, Monocalcium Salt, Malonic Acid, Dipotassium Salt, Alpha,Omega Dicarboxylic Acid, Malonic Acid, 2 (14)C Labeled, Malonic Acid, Diammonium Salt, Malonic Acid, Dithallium Salt, Malonic Acid, Monosodium Salt, Malonic Acid, Potassium Salt, Malonic Acid, Disodium Salt, Malonate Dicarboxylic Acid, Malonic Acid, Sodium Salt, Metahnedicarboxylic Acid, Methanedicarboxylic Acid, Methanedicarbonic Acid, Dithallium Malonate, Monosodium Malonate, Carboxyacetic Acid, Propanediolic Acid, Propanedioic Acid, Dicarboxylic Acid, Kyselina Malonova, Thallium Malonate, Thallous Malonate, Dicarboxymethane, Hooc Ch2 Cooh, Propanedioate, Dicarboxylate, Malonate, H2 Malo, Propanedioic Acid-2-13C, 1,3-Propanedioic Acid-2-13C, Carboxyacetic Acid-2-13C, Dicarboxymethane-2-13C, Methanedicarboxylic Acid-2-13C, NSC 8124-2-13C, Malonic-2-13C Acid, [2-13C]Malonic Acid



Propanedioic acid (Malonic acid), Reagent is a dicarboxylic acid which name originates from the Greek work, malon, meaning apple.
Propanedioic acid (Malonic acid) contains calcium salt in high concentrations of beetroot.
Normally Propanedioic acid (Malonic acid) appears as white crystals.


Propanedioic acid (Malonic acid) is an aliphatic dicarboxylic acid also referred to as propanedioic acid.
On the Kofler bench, the powdery body melts around 136°C and evaporates gradually.
Some impurities coat crystals which makes the determination of the melting point of Propanedioic acid (Malonic acid) very imprecise.


Propanedioic acid (Malonic acid) is a dicarboxylic acid with structure CH2(COOH)2.
The ionized form of Propanedioic acid (Malonic acid), as well as its esters and salts, are known as malonates.
Propanedioic acid (Malonic acid) acts as a building block in organic synthesis.


Propanedioic acid (Malonic acid) is also useful as a precursor for polyesters and alkyd resins, which is used in coating applications, thereby protecting against UV light, corrosion and oxidation.
Propanedioic acid (Malonic acid) acts as a cross linker in the coating industry and surgical adhesive.


Propanedioic acid (Malonic acid) is soluble in cold water.
Propanedioic acid (Malonic acid) is a dicarboxylic acid with structure CH2(COOH)2.
Propanedioic acid (Malonic acid) has three kinds of crystal forms, of which two are triclinic, and one is monoclinic.


That crystallized from ethanol is white triclinic crystals.
Propanedioic acid (Malonic acid) decomposes to acetic acid and carbon dioxide at 140℃.
Propanedioic acid (Malonic acid) does not decompose at 1.067×103~1.333×103Pa vacuum, but directly sublimates.


The ionised form of Propanedioic acid (Malonic acid), as well as its esters and salts, are known as malonates.
For example, diethyl malonate is Propanedioic acid (Malonic acid)'s ethyl ester.
The name originates from Latin malum, meaning apple.


Propanedioic acid (Malonic acid) is an alpha,omega-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group.
Propanedioic acid (Malonic acid) has a role as a human metabolite.
Propanedioic acid (Malonic acid) is a conjugate acid of a malonate(1-).


Propanedioic acid (Malonic acid) is white crystals or crystalline powder.
Propanedioic acid (Malonic acid) sublimes in vacuum.
Propanedioic acid (Malonic acid) is water soluble.


Propanedioic acid (Malonic acid), also known as propanedioic acid, is a dicarboxylic acid with the chemical formula C3H4O4.
Propanedioic acid (Malonic acid) is a white crystalline solid with a sour taste and is soluble in water and ethanol.
Propanedioic acid (Malonic acid) is an alpha,omega-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group.


Propanedioic acid (Malonic acid) is a dicarboxylic acid.
Propanedioic acid (Malonic acid) is a dicarboxylic acid with structure CH2(COOH)2.
The ionized form of Propanedioic acid (Malonic acid), as well as its esters and salts, are known as malonates.


Propanedioic acid (Malonic acid) has the chemical formula C3H4O4.
Propanedioic acid (Malonic acid) appears as a white, odorless crystal or crystalline powder.
Propanedioic acid (Malonic acid) is soluble in Water, Ether, and Alcohol.


Propanedioic acid (Malonic acid) is also known as Propanedioic acid or Dicarboxymethane.
The name is derived from the Greek word Malon which means apple.
Malonate is the ionized form of Propanedioic acid (Malonic acid), along with its esters and salt.


Propanedioic acid (Malonic acid) appears as a white crystal or crystalline powder.
Propanedioic acid (Malonic acid) dissolves in alcohol, pyridine, and ether.
Propanedioic acid (Malonic acid) was first prepared in the year, 1858 by the French chemist Victor Dessaignes by the oxidation of malic acid.


Propanedioic acid (Malonic acid) is found in some fruits viz citrus fruits.
Propanedioic acid (Malonic acid) can be produced through the fermentation of glucose.
Industrially, Propanedioic acid (Malonic acid) is produced by the hydrolysis of diethyl malonate or dimethyl malonate.


Propanedioic acid (Malonic acid) is a forerunner to polyester specialities.
Propanedioic acid (Malonic acid) is a dicarboxylic acid with structure CH2(COOH)2.
The ionised form of Propanedioic acid (Malonic acid), as well as its esters and salts, are known as malonates.


For example, diethyl malonate is Propanedioic acid (Malonic acid)'s ethyl ester.
The name originates from Latin malum, meaning apple.
Propanedioic acid (Malonic acid) is the archetypal example of a competitive inhibitor: It acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain.


Propanedioic acid (Malonic acid) has the chemical formula C3H4O4.
Propanedioic acid (Malonic acid) appears as a white, odorless crystal or crystalline powder.
Propanedioic acid (Malonic acid) is soluble in Water, Ether, and Alcohol.


Upon heating to decomposition temperature, Propanedioic acid (Malonic acid) emits irritating fumes and acrid smoke.
Propanedioic acid (Malonic acid) acts as a precursor for conversion to 1,3-propanediol, which is a compound used in polyesters and polymers with the huge market size.


Propanedioic acid (Malonic acid), also known as malonate or H2MALO is a dicarboxylic acid with structure CH2(COOH)2, belonging to the class of organic compounds known as dicarboxylic acids and derivatives.
These are organic compounds containing exactly two carboxylic acid groups.


The ionised form of Propanedioic acid (Malonic acid), as well as its esters and salts, are known as malonates.
For example, diethyl malonate is Propanedioic acid (Malonic acid)'s ethyl ester.
The name originates from Latin malum, meaning apple.


Propanedioic acid (Malonic acid) is the archetypal example of a competitive inhibitor: it acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain.
Propanedioic acid (Malonic acid) is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.


Propanedioic acid (Malonic acid) exists in all living species, ranging from bacteria to humans.
Within humans, Propanedioic acid (Malonic acid) participates in a number of enzymatic reactions.
In particular, Propanedioic acid (Malonic acid) and acetic acid can be converted into acetoacetic acid, which is mediated by the enzyme fatty acid synthase.


Beta ketoacyl synthase domain.
In addition, Propanedioic acid (Malonic acid)d and coenzyme A can be biosynthesized from malonyl-CoA through its interaction with the enzyme fatty acid synthase. malonyl/acetyl transferase domain.


A Propanedioic acid (Malonic acid) in which the two carboxy groups are separated by a single methylene group.
In humans, Propanedioic acid (Malonic acid) is involved in fatty acid biosynthesis.
Outside of the human body, Propanedioic acid (Malonic acid) has been detected, but not quantified in, several different foods, such as red beetroots, corns, scarlet beans, common beets, and cow milks.


This could make Propanedioic acid (Malonic acid) a potential biomarker for the consumption of these foods.
Propanedioic acid (Malonic acid), also known as malonate or H2MALO, belongs to the class of organic compounds known as dicarboxylic acids and derivatives.


These are organic compounds containing exactly two carboxylic acid groups.
Propanedioic acid (Malonic acid) is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.
Propanedioic acid (Malonic acid) exists in all living species, ranging from bacteria to humans.


Within yeast, Propanedioic acid (Malonic acid) participates in a number of enzymatic reactions.
In particular, Propanedioic acid (Malonic acid) and acetic acid can be converted into acetoacetic acid through the action of the enzyme fatty acid synthase.


Beta ketoacyl synthase domain.
In addition, Propanedioic acid (Malonic acid) can be biosynthesized from malonyl-CoA through its interaction with the enzyme fatty acid synthase. malonyl/acetyl transferase domain.


In yeast, Propanedioic acid (Malonic acid) is involved in the metabolic pathway called fatty acid biosynthesis pathway.
Propanedioic acid (Malonic acid) has a white crystal or crystalline powder structure.
Propanedioic acid (Malonic acid) is naturally occurring and can be found in many vegetables, fruits.


Propanedioic acid (Malonic acid) was first prepared by Victor Dessaignes by the oxidation reaction of malic acid.
Propanedioic acid (Malonic acid) is the second smallest aliphatic dicarboxylic acid with oxalic acid being the smallest.
Propanedioic acid (Malonic acid) can be confused with maleic or malic acid as both contain two carboxyl groups, but it is different.


Propanedioic acid (Malonic acid) differs from these two acids in terms of properties, structure, etc.
The name of Propanedioic acid (Malonic acid) is derived from the Greek word Malon which means apple.
Propanedioic acid (Malonic acid) on heating gives acetic acid.


French Chemist Victor Dessaignes was the first person to prepare this acid in 1858 by oxidation of malic acid.
Its name originated from the Greek word Malon which means Apple.
It is because Propanedioic acid (Malonic acid) is found in some fruits.


Greater concentrations of Propanedioic acid (Malonic acid) in citrus are found in fruits generated in organic farming compared to fruits generated in conventional farming.
Propanedioic acid (Malonic acid) is a white crystalline substance that quickly dissolves in water and oxygenated solutions.


Propanedioic acid (Malonic acid) has a breakdown temperature of 135 °C.
Its ionized form, esters and salts are known as malonates, such as the diethyl malonate, which is Propanedioic acid (Malonic acid)’s diethyl ester.
The molecular weight of Propanedioic acid (Malonic acid) is 104.061 g/mol, and its density is 1.619g/cm3.


Its melting point is 135 to 137°C and Propanedioic acid (Malonic acid) decomposes above the boiling point of 140°C.
Propanedioic acid (Malonic acid) is a dicarboxylic acid with structure CH2(COOH)2.
The ionised form of Propanedioic acid (Malonic acid), as well as its esters and salts, are known as malonates.


For example, diethyl malonate is Propanedioic acid (Malonic acid)'s ethyl ester.
The name of Propanedioic acid (Malonic acid) originates from Latin malum, meaning apple.
Propanedioic acid (Malonic acid) is a dicarboxylic acid with structure CH2(COOH)2.


The ionized form of Propanedioic acid (Malonic acid), as well as its esters and salts, are known as malonates.
For example, diethyl malonate is Propanedioic acid (Malonic acid)'s diethyl ester.
The name originates from the Greek word μᾶλον (malon) meaning 'apple'.


Propanedioic acid (Malonic acid) appears as white crystals or crystalline powder.
Propanedioic acid (Malonic acid) appears as white crystals or crystalline powder.
Propanedioic acid (Malonic acid) is an alpha,omega-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group.


Propanedioic acid (Malonic acid) has a role as a human metabolite.
Propanedioic acid (Malonic acid) is an alpha,omega-dicarboxylic acid and a lipid.
Propanedioic acid (Malonic acid) is a conjugate acid of a malonate(1-).


Propanedioic acid (Malonic acid) is soluble in cold water.
Propanedioic acid (Malonic acid), also known as malonate or H2MALO, belongs to the class of organic compounds known as dicarboxylic acids and derivatives.


These are organic compounds containing exactly two carboxylic acid groups.
Propanedioic acid (Malonic acid) is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.
Propanedioic acid (Malonic acid) exists in all living species, ranging from bacteria to humans.


Within yeast, Propanedioic acid (Malonic acid) participates in a number of enzymatic reactions.
In particular, Propanedioic acid (Malonic acid) and acetic acid can be converted into acetoacetic acid through the action of the enzyme fatty acid synthase.


Beta ketoacyl synthase domain.
In addition, Propanedioic acid (Malonic acid) can be biosynthesized from malonyl-CoA through its interaction with the enzyme fatty acid synthase. malonyl/acetyl transferase domain.


In yeast, Propanedioic acid (Malonic acid) is involved in the metabolic pathway called fatty acid biosynthesis pathway.
Propanedioic acid (Malonic acid), also known as malonate or H2MALO, belongs to the class of organic compounds known as dicarboxylic acids and derivatives.


These are organic compounds containing exactly two carboxylic acid groups.
Propanedioic acid (Malonic acid) is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.
Propanedioic acid (Malonic acid) exists in all living species, ranging from bacteria to humans.


Within humans, Propanedioic acid (Malonic acid) participates in a number of enzymatic reactions.
In particular, Propanedioic acid (Malonic acid) and acetic acid can be converted into acetoacetic acid; which is mediated by the enzyme fatty acid synthase.


Beta ketoacyl synthase domain.
In addition, Propanedioic acid (Malonic acid) and coenzyme A can be biosynthesized from malonyl-CoA through its interaction with the enzyme fatty acid synthase.


malonyl/acetyl transferase domain.
An Propanedioic acid (Malonic acid) in which the two carboxy groups are separated by a single methylene group.
In humans, Propanedioic acid (Malonic acid) is involved in fatty acid biosynthesis.


Outside of the human body, Propanedioic acid (Malonic acid) has been detected, but not quantified in, several different foods, such as red beetroots, corns, scarlet beans, common beets, and cow milks.
This could make Propanedioic acid (Malonic acid) a potential biomarker for the consumption of these foods.


Propanedioic acid (Malonic acid), with regard to humans, has been found to be associated with several diseases such as eosinophilic esophagitis, combined malonic and methylmalonic aciduria, and early preeclampsia; Propanedioic acid (Malonic acid) has also been linked to the inborn metabolic disorder malonyl-coa decarboxylase deficiency.


Propanedioic acid (Malonic acid) belongs to the class of organic compounds known as dicarboxylic acids and derivatives.
These are organic compounds containing exactly two carboxylic acid groups.
Propanedioic acid (Malonic acid) is a dicarboxylic acid that forms a solid at room temperature.


Propanedioic acid (Malonic acid) is a dicarboxylic acid used as a precursor to certain polyesters and is a component in alkyd resins.
Propanedioic acid (Malonic acid) is a dicarboxylic acid belonging to the family of carboxylic acids.
A dicarboxylic acid contains two carboxylic acid functional groups. Usually, a dicarboxylic acid exhibits the same chemical behavior as monocarboxylic acids.


This naturally occurs in certain fruits.
Propanedioic acid (Malonic acid) is a useful organic compound with various benefits.
Propanedioic acid (Malonic acid)'s IUPAC name is propanedioic acid.


Propanedioic acid (Malonic acid) should not be confused with malic or maleic acid.
Propanedioic acid (Malonic acid) is a dicarboxylic acid with the chemical formula C3H4O4.
Dicarboxylic acids are organic compounds containing two carboxylic acid functional groups.


Dicarboxylic acids generally show the same chemical behaviour and reactivity as monocarboxylic acids.
Propanedioic acid (Malonic acid) is a substance found in some fruits that occurs naturally.
Fruits generated in organic farming contain greater concentrations of Propanedioic acid (Malonic acid) in citrus compared to fruits generated in conventional farming.


The IUPAC name of Propanedioic acid (Malonic acid) is propanedioic acid.
Propanedioic acid (Malonic acid) is the archetypal instance of a competitive inhibitor: it functions in the respiratory electron transport chain against succinate dehydrogenase.


Propanedioic acid (Malonic acid) is correlated with deficiency of malonyl-CoA decarboxylase, an inborn metabolism mistake.
Propanedioic acid (Malonic acid) appears as white crystals or crystalline powder.
Propanedioic acid (Malonic acid) sublimes in vacuum.


Propanedioic acid (Malonic acid) is an alpha,omega-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group.
Propanedioic acid (Malonic acid) has a role as a human metabolite.
Propanedioic acid (Malonic acid) is a conjugate acid of a malonate(1-).


Propanedioic acid (Malonic acid) is a natural product found in Camellia sinensis, Meum athamanticum, and other organisms with data available.
Propanedioic acid (Malonic acid) is a dicarboxylic acid with structure CH2(COOH)2.
The ionized form of malonic acid, as well as its esters and salts, are known as malonates.


For example, diethyl malonate is malonic acid's diethyl ester.
The name of Propanedioic acid (Malonic acid) originates from the Greek word μᾶλον (malon) meaning 'apple'.



USES and APPLICATIONS of PROPANEDIOIC ACID (MALONIC ACID):
Propanedioic acid (Malonic acid) finds application in the production of specialty chemicals, flavors and fragrances, polymer cross linkers and pharmaceuticals.
Propanedioic acid (Malonic acid) acts as a building block in organic synthesis.


Propanedioic acid (Malonic acid) is also useful as a precursor for polyesters and alkyd resins, which are used in coating applications, thereby protecting against UV light, corrosion and oxidation.
Propanedioic acid (Malonic acid) acts as a cross linker in the coating industry and surgical adhesive.


Propanedioic acid (Malonic acid) finds application in the production of specialty chemicals, flavors and fragrances, polymer cross linkers and pharmaceuticals.
Propanedioic acid (Malonic acid) is used to produce an enhanced starch-based resin, which is environmentally-benign, uses water-based processing without toxic catalysts.


Propanedioic acid (Malonic acid) is used in the synthesis of barbituric acid and its derivatives.
Propanedioic acid (Malonic acid) was discovered and identified in 1858 from the oxidation products of apple juice.
Propanedioic acid (Malonic acid) is present as a white crystalline powder with no odor but with a high vapor pressure at room temperature.


Propanedioic acid (Malonic acid) is however easily soluble in water as well as in pyridine, ethanol, methanol and ether.
Propanedioic acid (Malonic acid) is not soluble in benzene.
Propanedioic acid (Malonic acid) is used as an intermediate in the manufacture of barbiturates and other pharmaceuticals.


Propanedioic acid (Malonic acid) is a component used as a stabilizer in many high-end cosmetic and pharmaceutical products.
Propanedioic acid (Malonic acid) is also used as building block in chemical synthesis, specifically to introduce the molecular group -CH2-COOH.
Propanedioic acid (Malonic acid) is used for the introduction of an acetic acid moiety under mild conditions by Knoevenagel condensation and subsequent decarboxylation.


Propanedioic acid (Malonic acid) is acts as a building block in organic synthesis.
Propanedioic acid (Malonic acid) is also useful as a precursor for polyesters and alkyd resins, which is used in coating applications, thereby protecting against UV light, corrosion and oxidation.


Propanedioic acid (Malonic acid) acts as a cross linker in the coating industry and surgical adhesive.
Propanedioic acid (Malonic acid) finds application in the production of specialty chemicals, flavors and fragrances, polymer cross linkers and pharmaceuticals.


Propanedioic acid (Malonic acid) is commonly used in organic synthesis, specifically in the production of pharmaceuticals, agrochemicals, and fragrances.
Propanedioic acid (Malonic acid) is also used as a pH adjuster in the food industry.
The chemical properties of Propanedioic acid (Malonic acid) make it a unique and versatile compound in organic chemistry.


Propanedioic acid (Malonic acid) contains two carboxylic acid groups (-COOH) which make it a weak acid with a pKa of 2.8.
Additionally, the presence of two carbonyl groups (-C=O) make Propanedioic acid (Malonic acid) a useful compound in organic synthesis.
Propanedioic acid (Malonic acid) is often used as a building block in the synthesis of various organic compounds due to its ability to undergo nucleophilic substitution reactions.


Propanedioic acid (Malonic acid) is also known for its ability to form stable complexes with metal ions.
This property is utilized in analytical chemistry for the determination of metal ions in various samples.
Propanedioic acid (Malonic acid) can form chelates with metal ions such as calcium, magnesium, and iron, which are then easily detected and quantified.


In conclusion, Propanedioic acid (Malonic acid) is a versatile compound with a wide range of applications in various fields.
Its unique chemical properties make Propanedioic acid (Malonic acid) a useful building block in organic synthesis and a valuable reagent in analytical chemistry.


Propanedioic acid (Malonic acid) is used to produce an enhanced starch-based resin, which is environmentally-benign, uses water-based processing without toxic catalysts.
Propanedioic acid (Malonic acid) may be used as a cross-linking agent between corn starch and potato starch to improve its mechanical properties.


Propanedioic acid (Malonic acid) can be converted into 1,3-propanediol for use in polyesters and polymers (whose usefulness is unclear though).
Propanedioic acid (Malonic acid) can also be a component in alkyd resins, which are used in a number of coatings applications for protecting against damage caused by UV light, oxidation, and corrosion.


One application of Propanedioic acid (Malonic acid) is in the coatings industry as a crosslinker for low-temperature cure powder coatings, which are becoming increasingly valuable for heat sensitive substrates and a desire to speed up the coatings process.
The global coatings market for automobiles was estimated to be $18.59 billion in 2014 with projected combined annual growth rate of 5.1% through 2022.


Propanedioic acid (Malonic acid) is used in a number of manufacturing processes as a high value specialty chemical including the electronics industry, flavors and fragrances industry, specialty solvents, polymer crosslinking, and pharmaceutical industry.
In 2004, annual global production of Propanedioic acid (Malonic acid) and related diesters was over 20,000 metric tons.


Potential growth of these markets could result from advances in industrial biotechnology that seeks to displace petroleum-based chemicals in industrial applications.
In 2004, Propanedioic acid (Malonic acid) was listed by the US Department of Energy as one of the top 30 chemicals to be produced from biomass.


In food and drug applications, Propanedioic acid (Malonic acid) can be used to control acidity, either as an excipient in pharmaceutical formulation or natural preservative additive for foods.
Propanedioic acid (Malonic acid) is used as a building block chemical to produce numerous valuable compounds, including the flavor and fragrance compounds gamma-nonalactone, cinnamic acid, and the pharmaceutical compound valproate.


Propanedioic acid (Malonic acid) has been used to cross-link corn and potato starches to produce a biodegradable thermoplastic; the process is performed in water using non-toxic catalysts.
Starch-based polymers comprised 38% of the global biodegradable polymers market in 2014 with food packaging, foam packaging, and compost bags as the largest end-use segments.


Propanedioic acid (Malonic acid) is used as a precursor in polymers and polyester.
Propanedioic acid (Malonic acid) is used in flavours as well as in the fragrance industry.
Propanedioic acid (Malonic acid) is used to control acidity.


Propanedioic acid (Malonic acid) is used in pharmaceutical products.
Propanedioic acid (Malonic acid) is used as a cross-linking agent between potato starch and cornstarch to enhance its mechanical properties.
Propanedioic acid (Malonic acid) is used for the preparation of cinnamic acid, a compound used for the formation of cin metacin which is an anti-inflammatory.


The malonates are used in syntheses of B1 and B6, barbiturates, and several other valuable compounds.
Common Uses of Propanedioic acid (Malonic acid): Plating agent, Surface treating agent, Intermediate, Buffer, ans Cross-linking agent.
Commercial/Industrial Applications of Propanedioic acid (Malonic acid) :Laboratory chemicals, Pharmaceuticals, and Paint industry.


Propanedioic acid (Malonic acid) is used in cosmetics as a buffering and as a flavouring agent in food.
Propanedioic acid (Malonic acid) is used as a component of alkyd resins.
Propanedioic acid (Malonic acid) is used in coating applications to protect from UV rays, oxidation, and corrosion.


Propanedioic acid (Malonic acid) is a building block to many valuable compounds in food and drug applications, pharmaceutical, electronics industry, fragrances, specialty polymer, specialty solvents, and many more.
Propanedioic acid (Malonic acid) is used as a cross-linking agent between cornstarch and potato starch to enhance its mechanical properties.


Propanedioic acid (Malonic acid) is used as a precursor in polymers and polyester and is used to produce vitamin B1, vitamin B6, vitamin B2, and amino acids.
Propanedioic acid (Malonic acid) is used in flavors as well as in the fragrance industry and electroplating.
Propanedioic acid (Malonic acid) is a precursor to specialty polyesters.


Propanedioic acid (Malonic acid) is also used in chemical synthesis as a building block and is used to control acidity.
Propanedioic acid (Malonic acid) is used in pharmaceutical products and the preparation of barbituric salt.
Propanedioic acid (Malonic acid) acts as a building block in organic synthesis.


Propanedioic acid (Malonic acid) is also useful as a precursor for polyesters and alkyd resins, which are used in coating applications, thereby protecting against UV light, corrosion and oxidation.
Propanedioic acid (Malonic acid) acts as a cross linker in the coating industry and surgical adhesive.


Propanedioic acid (Malonic acid) finds application in the production of specialty chemicals, flavors and fragrances, polymer cross linkers and pharmaceuticals.
Propanedioic acid (Malonic acid) is acts as a building block in organic synthesis.


Propanedioic acid (Malonic acid) is also useful as a precursor for polyesters and alkyd resins, which are used in coating applications, thereby protecting against UV light, corrosion and oxidation.
Propanedioic acid (Malonic acid) acts as a cross linker in the coating industry and surgical adhesive.


Propanedioic acid (Malonic acid) finds application in the production of specialty chemicals, flavors and fragrances, polymer cross linkers and pharmaceuticals.
This dicarboxylic acid, Propanedioic acid (Malonic acid), finds application across various industries, including automobiles, food, fragrance, and pharmaceuticals.


Propanedioic acid (Malonic acid) is used as a precursor in polyester and other polymers.
Propanedioic acid (Malonic acid) is used as a flavoring agent in the fragrance industry.
Propanedioic acid (Malonic acid) is suitable for controlling acidity.


Propanedioic acid (Malonic acid) finds usage in pharmaceutical products.
Propanedioic acid (Malonic acid) is used in the manufacture of biodegradable containers.
Propanedioic acid (Malonic acid) is also a component of surgical adhesives.


Propanedioic acid (Malonic acid) serves as a cross-linking agent between cornstarch and potato starch to enhance its properties.
Propanedioic acid (Malonic acid) is used for the preparation of barbituric salt.
Propanedioic acid (Malonic acid) is used in electroplating.


Propanedioic acid (Malonic acid) is used in the production of vitamins– B1, B6, B2, and amino acids.
Propanedioic acid (Malonic acid) can also be used as a component in alkyd resins.
Propanedioic acid (Malonic acid) is widely used in several coating applications to protect objects against UV light damage, oxidation, and corrosion.


A common application of Propanedioic acid (Malonic acid) is as a crosslinker for low-temperature powder coatings.
These are valuable for heat-sensitive substrates.
Propanedioic acid (Malonic acid) is on the US Department of Energy’s list of top chemicals for biomass production.


In food and drug applications, Propanedioic acid (Malonic acid) acts as a natural preservative additive for foods.
Its therapeutic uses include the prevention of resorption of bone tissue in broiler chicks by adding Propanedioic acid (Malonic acid) to feed.
Propanedioic acid (Malonic acid) is a common intermediate in the pharmaceutical industry and is frequently used in veterinary medicine.


Propanedioic acid (Malonic acid) is also used as a flavouring agent in certain foods.
Propanedioic acid (Malonic acid) is used to generate countless useful compounds as a construction block chemical.
Propanedioic acid (Malonic acid) is used in the preparation of barbituric salt.


Propanedioic acid (Malonic acid) is used in electroplating.
Propanedioic acid (Malonic acid) is used to produce vitamin B1, vitamin B6, vitamin B2, and amino acids.
Propanedioic acid (Malonic acid) is used in chemical synthesis as a building block.


-Biotechnological Applications of Propanedioic acid (Malonic acid):
The calcium salt of Propanedioic acid (Malonic acid) occurs in high concentrations in beetroot.
Propanedioic acid (Malonic acid) exists in its normal state as white crystals.
Propanedioic acid (Malonic acid) is the classic example of a competitive inhibitor.
Propanedioic acid (Malonic acid) acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain.



CHEMICAL PROPERTIES OF PROPANEDIOIC ACID (MALONIC ACID):
Propanedioic acid (Malonic acid) is a white crystalline solid that decomposes at approximately 135°C.
Propanedioic acid (Malonic acid) has high solubility in water and oxygenated solvents and exhibits greater acidity than acetic acid, which has a pK value of 4.75.

The pKa values for the loss of Propanedioic acid (Malonic acid)'s first and second protons are 2.83 and 5.69, respectively.
Propanedioic acid (Malonic acid) is slightly soluble in pyridine.

Propanedioic acid (Malonic acid) can decompose to formic acid and carbon dioxide in case of potassium permanganate.
Since Propanedioic acid (Malonic acid) generates carbon dioxide and water after heated without pollution problems, it can be directly used as aluminum surface treatment agent.



PREPARATION OF PROPANEDIOIC ACID (MALONIC ACID):
Propanedioic acid (Malonic acid) is usually produced from chloroacetic acid.



REACTIONS OF PROPANEDIOIC ACID (MALONIC ACID):
The chloroacetic acid is added to the reaction kettle by adding sodium carbonate aqueous solution to generate sodium chloroacetate aqueous solution, and then 30% sodium cyanide solution is slowly added dropwise, and the reaction is carried out at a predetermined temperature to generate sodium cyanoacetate.
After the cyanation reaction is completed, add sodium hydroxide for heating and hydrolysis to generate sodium malonate solution, concentrate, then dropwise add sulfuric acid for acidification to generate Propanedioic acid (Malonic acid), filter and dry to obtain the product.



PREPARATION OF PROPANEDIOIC ACID (MALONIC ACID):
This method often does not produce a pure enough product or the pure product has an extremely low yield.
Industrially, Propanedioic acid (Malonic acid) is also produced by hydrolyzing dimethyl malonate or diethyl malonate.
This manufacturing method is able to bring about a higher yield and purity, but the organic synthesis of Propanedioic acid (Malonic acid) through these processes is extremely costly and environmentally hazardous.



STRUCTURE OF PROPANEDIOIC ACID (MALONIC ACID):
Malonic acid Synthesis – C3H4O4:
Preparation of Propanedioic acid (Malonic acid) starts with chloroacetic acid which is also known as MCA (monochloroacetic acid).

Step 1: Sodium carbonate produces sodium salt.
Step 2: It is made to react with sodium cyanide.
Step 3: cyanoacetic acid salt is generated through nucleophilic substitution.
Step 4: The nitrile group is hydrolyzed with sodium hydroxide to produce sodium malonate.
Step 5: The acidification results in Propanedioic acid (Malonic acid).



ALTERNATIVE PARENTS OF PROPANEDIOIC ACID (MALONIC ACID):
*1,3-dicarbonyl compounds
*Carboxylic acids
*Organic oxides
*Hydrocarbon derivatives



SUBSTITUENTS OF PROPANEDIOIC ACID (MALONIC ACID):
*1,3-dicarbonyl compound
*Dicarboxylic acid or derivatives
*Carboxylic acid
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Organooxygen compound
*Carbonyl group
*Aliphatic acyclic compound



STRUCTURE AND PREPARATION OF PROPANEDIOIC ACID (MALONIC ACID):
The structure has been determined by X-ray crystallography and extensive property data including for condensed phase thermochemistry are available from the National Institute of Standards and Technology.
A classical preparation of Propanedioic acid (Malonic acid) starts from chloroacetic acid:


*Preparation of Propanedioic acid (Malonic acid) from chloroacetic acid.
Sodium carbonate generates the sodium salt, which is then reacted with sodium cyanide to provide the sodium salt of cyanoacetic acid via a nucleophilic substitution.

The nitrile group can be hydrolyzed with sodium hydroxide to sodium malonate, and acidification affords Propanedioic acid (Malonic acid).
Industrially, however, Propanedioic acid (Malonic acid) is produced by hydrolysis of dimethyl malonate or diethyl malonate.
Propanedioic acid (Malonic acid) has also been produced through fermentation of glucose.


*Organic reactions:
Propanedioic acid (Malonic acid) reacts as a typical carboxylic acid: forming amide, ester, anhydride, and chloride derivatives.
Malonic anhydride can be used as an intermediate to mono-ester or amide derivatives, while malonyl chloride is most useful to obtain diesters or diamides.

In a well-known reaction, Propanedioic acid (Malonic acid) condenses with urea to form barbituric acid.
Propanedioic acid (Malonic acid) may also be condensed with acetone to form Meldrum's acid, a versatile intermediate in further transformations.
The esters of Propanedioic acid (Malonic acid) are also used as a −CH2COOH synthon in the malonic ester synthesis.


*Mitochondrial fatty acid synthesis:
Propanedioic acid (Malonic acid) is the starting substrate of mitochondrial fatty acid synthesis (mtFASII), in which it is converted to malonyl-CoA by malonyl-CoA synthetase (ACSF3).

Additionally, the coenzyme A derivative of malonate, malonyl-CoA, is an important precursor in cytosolic fatty acid biosynthesis along with acetyl CoA.
Malonyl CoA is formed there from acetyl CoA by the action of acetyl-CoA carboxylase, and the malonate is transferred to an acyl carrier protein to be added to a fatty acid chain.


*Briggs–Rauscher reaction:
Propanedioic acid (Malonic acid) is a key component in the Briggs–Rauscher reaction, the classic example of an oscillating chemical reaction.


*Knoevenagel condensation:
In Knoevenagel condensation, Propanedioic acid (Malonic acid) or its diesters are reacted with the carbonyl group of an aldehyde or ketone, followed by a dehydration reaction.

When Propanedioic acid (Malonic acid) itself is used, it is normally because the desired product is one in which a second step has occurred, with loss of carbon dioxide, in the so-called Doebner modification.

Thus, for example, the reaction product of acrolein and Propanedioic acid (Malonic acid) in pyridine is trans-2,4-Pentadienoic acid with one carboxylic acid group and not two.


*Preparation of carbon suboxide:
Carbon suboxide is prepared by warming a dry mixture of phosphorus pentoxide (P4O10) and Propanedioic acid (Malonic acid).
It reacts in a similar way to malonic anhydride, forming malonates.



FORMULA OF PROPANEDIOIC ACID (MALONIC ACID):
Propanedioic acid (Malonic acid) is a dicarboxylic acid with the chemical formula C3H4O4 and structural formula CH2(COOH)2.
Propanedioic acid is the IUPAC name of Propanedioic acid (Malonic acid), and another name for the acid is Methane Dicarboxylic acid.

Malonates are Propanedioic acid (Malonic acid)'s esters and salts.
There are three carbons with four hydrogen molecules and four oxygen molecules attached.
The two OH groups are attached with two carbons



SYNTHESIS OF PROPANEDIOIC ACID (MALONIC ACID):
The synthesis of Propanedioic acid (Malonic acid) starts with chloroacetic acid, also known as Monochloroacetic acid.
The following steps occur during the reaction:

Step 1:- Sodium salt is produced when sodium carbonate breaks down.
Step 2:- Then, the reaction of sodium salt with sodium cyanide is made to occur.
Step 3:- Through nucleophilic substitution, cyanoacetic acid salt is generated.
Step 4:- To produce sodium malonate, the nitrile group is hydrolyzed with sodium hydroxide.
Step 5:- Then the acidification yields Propanedioic acid (Malonic acid).



REACTION OF PROPANEDIOIC ACID (MALONIC ACID):
As with other carboxylic acids, Propanedioic acid (Malonic acid) reacts by producing derivatives of chloride, ester, anhydride, and amide.
Malonyl chloride is best for producing diamides or diesters, although malonic anhydride can be employed as an intermediary to produce mono-ester or amide derivatives.

Barbituric acid is created when Propanedioic acid (Malonic acid) and urea condense in a well-known process.
Additionally, acetone and propanedioic acid can be combined to generate Meldrum’s acid, a flexible intermediate used in other conversions.
Propanedioic acid (Malonic acid) esters are also utilised in the malonic ester production as a CH2COOH synthon.

Furthermore, the coenzyme Malonyl-CoA, a malonate derivative, is the main precursor in fatty acid biosynthesis, along with acetyl CoA.
By the action of acetyl-CoA carboxylase, malonyl CoA is generated from acetyl CoA, and the malonate is transported to an acyl carrier protein to be added to a fatty acid chain.

Following are the chemical reactions that involve the Propanedioic acid (Malonic acid):
*Briggs–Rauscher Reaction
*Knoevenagel condensation
*Preparation of carbon suboxide



IUPAC NAME OF PROPANEDIOIC ACID (MALONIC ACID):
Propanedioic acid (Malonic acid) is a dicarboxylic acid with structural formula CH2(COOH)2 and chemical formula C3H4O4.
The name Propanedioic acid (Malonic acid) originated from the word ‘Malon’ which is Greek for ‘apple’.
The IUPAC name of Propanedioic acid (Malonic acid) is Propanedioic acid.

Methane Dicarboxylic acid is another name for Propanedioic acid (Malonic acid).
The ester and salts of Propanedioic acid (Malonic acid) are called malonates.
The dicarboxylic acid has organic reactions similar to the monocarboxylic acid where amide, ester, anhydride, and chloride derivatives are formed.
Lastly, the malonic ester malonate as a coenzyme A derivative malonyl CoA that is as important a precursor as Acetyl CoA in the biosynthesis of fatty acids.



SYNTHESIS OF PROPANEDIOIC ACID (MALONIC ACID):
The synthesis of Propanedioic acid (Malonic acid) usually begins with chloroacetic acid.
Propanedioic acid (Malonic acid) is also synthesized by cyanoacetic acid or by acid saponification reaction of malonates.
From monochloroacetic acid, Propanedioic acid (Malonic acid) is produced by sodium or potassium cyanide.

The sodium carbonate primarily breaks down to give sodium salt which reacts with sodium cyanide to give sodium salt of cyanoacetic acid by the process of nucleophilic substitution.
Further, via hydrolyzation, the nitrile group binds with sodium malonate, whose acidification results in the production of Propanedioic acid (Malonic acid).



STRUCTURAL FORMULA OF PROPANEDIOIC ACID (MALONIC ACID):
The structural formula of Propanedioic acid (Malonic acid) can be given as:
The Propanedioic acid (Malonic acid) Lewis structure has been found by the X-ray crystallography method.
The Propanedioic acid (Malonic acid) structure CH2(COOH)2 has two carboxylic acids.
The salts and esters of malonic acid (malonates) have structures similar to Propanedioic acid (Malonic acid).



PROPERTIES OF PROPANEDIOIC ACID (MALONIC ACID):
Propanedioic acid (Malonic acid) molecular weight: 104.061 g.mol-1
The density of Propanedioic acid (Malonic acid) is 1.619 g/cm3.
Propanedioic acid (Malonic acid) appears as a crystalline powder that is white or colourless.

At the boiling point above 140oC Propanedioic acid (Malonic acid) decomposes.
The melting point of Propanedioic acid (Malonic acid) is 135-137o C.
If heated to decomposition under fire Propanedioic acid (Malonic acid) emits carbon oxide fumes and acrid irritating smoke.

Acidity pKa = 2.85 at 25oC.
pKa1 = 2.83, pKa2 = 5.69
The molar heat of combustion of Propanedioic acid (Malonic acid) is 864 kJ/mol.

The heat of vaporization of Propanedioic acid (Malonic acid) is 92 kJ/mol.
Propanedioic acid (Malonic acid) is soluble in water.
Solubility of Propanedioic acid (Malonic acid) is 763 g/L.



POLARITY AND SOLUBILITY OF PROPANEDIOIC ACID (MALONIC ACID):
Propanedioic acid (Malonic acid) is a dicarboxylic acid belonging to the family of carboxylic acids.
A dicarboxylic acid contains two carboxylic acid functional groups.
Usually, a dicarboxylic acid exhibits the same chemical behavior as monocarboxylic acids.

This naturally occurs in certain fruits.
Propanedioic acid (Malonic acid) is a useful organic compound with various benefits.
Propanedioic acid (Malonic acid)'s IUPAC name is propanedioic acid.

Propanedioic acid (Malonic acid) should not be confused with malic or maleic acid.
Propanedioic acid (Malonic acid) is an organic compound naturally found in some fruits.
Fruits produced in organic farming have greater concentrations of Propanedioic acid (Malonic acid) than those generated from conventional farming practices.

Propanedioic acid (Malonic acid) is often found in some citrus fruits and vegetables.
Propanedioic acid (Malonic acid) is a component of food items, it is present in animals, including humans.



POLARITY OF PROPANEDIOIC ACID (MALONIC ACID):
Carboxyl group is polar as there is a large difference in the electronegativity values of oxygen and hydrogen.
Propanedioic acid (Malonic acid) has two carboxyl groups and only three carbon atoms, which has little effect on polarity, so the malonic acid molecule is polar.



SOLUBILITY OF PROPANEDIOIC ACID (MALONIC ACID):
Sample of Propanedioic acid (Malonic acid) was tested with water, methyl alcohol, and hexane.
Propanedioic acid (Malonic acid) was soluble in water because both malonic acid and water are polar.
Propanedioic acid (Malonic acid) took 25 seconds for malonic acid to dissolve in water.

Propanedioic acid (Malonic acid) was soluble in methyl alcohol because malonic acid is polar and methyl alcohol is intermediately polar, allowing malonic acid to dissolve in the methanol in 15 seconds.
Propanedioic acid (Malonic acid) was insoluble in hexane because hexane is nonpolar while malonic acid is polar.



HISTORY OF PROPANEDIOIC ACID (MALONIC ACID):
Propanedioic acid (Malonic acid) is a naturally occurring substance found in many fruits and vegetables.
There is a suggestion that citrus fruits produced in organic farming contain higher levels of Propanedioic acid (Malonic acid) than fruits produced in conventional agriculture.
Propanedioic acid (Malonic acid) was first prepared in 1858 by the French chemist Victor Dessaignes via the oxidation of malic acid.



REACTIONS OF PROPANEDIOIC ACID (MALONIC ACID):
In a well - known reaction, Propanedioic acid (Malonic acid) condenses with urea to form barbituric acid.
Propanedioic acid (Malonic acid) is also frequently used as an enolate in Knoevenagel condensations or condensed with acetone to form Meldrum's acid.
The esters of Propanedioic acid (Malonic acid) are also used as a - CH2COOH synthon in the malonic ester synthesis.



BIOLOGICAL FUNCTIONS OF PROPANEDIOIC ACID (MALONIC ACID):
Propanedioic acid (Malonic acid) is the classic example of a competitive inhibitor of the enzyme succinate dehydrogenase (complex II), in the respiratory electron transport chain.

Propanedioic acid (Malonic acid) binds to the active site of the enzyme without reacting, competing with the usual substrate succinate but lacking the ?CH2CH2? group required for dehydrogenation.
This observation was used to deduce the structure of the active site in succinate dehydrogenase.



REACTIVITY PROFILE OF PROPANEDIOIC ACID (MALONIC ACID):
Propanedioic acid (Malonic acid) is a carboxylic acid.
Carboxylic acids donate hydrogen ions if a base is present to accept them.
They react in this way with all bases, both organic (for example, the amines) and inorganic.

Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat.
Neutralization between an acid and a base produces water plus a salt.
Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water.

Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions.
The pH of solutions of carboxylic acids is therefore less than 7.0.
Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt.

Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt.
Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry.
Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in Propanedioic acid (Malonic acid) to corrode or dissolve iron, steel, and aluminum parts and containers.

Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents.
These reactions generate heat.
A wide variety of products is possible.

Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions.
Propanedioic acid (Malonic acid) is incompatible with strong oxidizers.
Propanedioic acid (Malonic acid) is also incompatible with bases and reducing agents.



PURIFICATION METHODS OF PROPANEDIOIC ACID (MALONIC ACID):
Crystallise Propanedioic acid (Malonic acid) from *benzene/diethyl ether (1:1) containing 5% of pet ether (b 60-80o), wash with diethyl ether, then recrystallise it from H2O or acetone.
Dry Propanedioic acid (Malonic acid) under vacuum over conc H2SO4.



PATHOLOGY OF PROPANEDIOIC ACID (MALONIC ACID):
If elevated Propanedioic acid (Malonic acid) levels are accompanied by elevated methylmalonic acid levels, this may indicate the metabolic disease combined malonic and methylmalonic aciduria (CMAMMA).
By calculating the Propanedioic acid (Malonic acid) to methylmalonic acid ratio in blood plasma, CMAMMA can be distinguished from classic methylmalonic acidemia.



BIOCHEMISTRY OF PROPANEDIOIC ACID (MALONIC ACID):
Propanedioic acid (Malonic acid) is the classic example of a competitive inhibitor of the enzyme succinate dehydrogenase (complex II), in the respiratory electron transport chain.
Propanedioic acid (Malonic acid) binds to the active site of the enzyme without reacting, competing with the usual substrate succinate but lacking the −CH2CH2− group required for dehydrogenation.

This observation was used to deduce the structure of the active site in succinate dehydrogenase.
Inhibition of this enzyme decreases cellular respiration.
Since Propanedioic acid (Malonic acid) is a natural component of many foods, it is present in mammals including humans.



RELATED CHEMICALS OF PROPANEDIOIC ACID (MALONIC ACID):
The fluorinated version of Propanedioic acid (Malonic acid) is difluoromalonic acid
Propanedioic acid (Malonic acid) is diprotic; that is, it can donate two protons per molecule.
Propanedioic acid (Malonic acid)'s first is 2.8 and the second is 5.7.

Thus the malonate ion can be HOOCCH2COO− or CH2(COO)2−2.
Malonate or propanedioate compounds include salts and esters of Propanedioic acid (Malonic acid), such as Diethyl malonate, Dimethyl malonate, Disodium malonate, and Malonyl-CoA.



CALCULATION OF MOLECULAR WEIGHT OF PROPANEDIOIC ACID (MALONIC ACID):
The formula of malonic acid is C3H4O4.
The atomic weight of carbon is 12.011.
The atomic weight of oxygen is 15.999.
The atomic weight of hydrogen is 1.00784.

So, its molar mass can be calculated as follows:
= (3 × 12.011) + (4 × 1.00784) + (4 × 15.999)
= 36.033 + 4. 03136 + 63.996
= 104.06 grams/ mol
Thus, the molar mass or molecular weight of Propanedioic acid (Malonic acid) is 104.061 g/mol.



CHEMICAL PROPERTIES OF PROPANEDIOIC ACID (MALONIC ACID):
The chemical properties of Propanedioic acid (Malonic acid) are as follows:

*On Heating
When It is heated, Propanedioic acid (Malonic acid) gives acetic acid and carbon dioxide.


*Reaction with Phosphorus Pentoxide
On heating a dry mixture of Propanedioic acid (Malonic acid) and phosphorus pentoxide, carbon suboxide is prepared.


*Decomposition
Propanedioic acid (Malonic acid) has hazardous decomposition products under fire conditions, including carbon oxides.
Also, when heated, Propanedioic acid (Malonic acid) decomposes and emits acrid smoke in addition to irritating fumes.


*Organic Reactions
Propanedioic acid (Malonic acid) reactions are usually similar to a typical carboxylic acid.
Propanedioic acid (Malonic acid) forms amide, anhydrides, esters, and chloride derivatives on reacting with specific reactants.

Malonic anhydride serves as an intermediate in the formation of amide derivatives.
Malonyl chloride is widely used for obtaining diamides or diesters.
Some of the popular organic reactions involving Propanedioic acid (Malonic acid) are as follows:

Propanedioic acid (Malonic acid) condenses with urea to give barbituric acid.
Propanedioic acid (Malonic acid) also condenses with acetone to produce Meldrum’s acid.
Propanedioic acid (Malonic acid) is a versatile intermediate and helps in further transformations.

Malonate’s coenzyme A derivative— malonyl-CoA, acts as an important precursor in fatty acid biosynthesis.
Propanedioic acid (Malonic acid) is formed from acetyl CoA when it is acted upon by acetyl-CoA carboxylase.
The malonate gets transferred to an acyl carrier protein for its addition to the fatty acid chain.


*Briggs–Rauscher Reaction
A popular name reaction has Propanedioic acid (Malonic acid) as its key component.
Propanedioic acid (Malonic acid) is an example of an oscillating chemical reaction.


*Knoevenagel Condensation
The reaction is a modification of the aldol condensation reaction (the reaction between benzaldehyde and acetophenone).
Propanedioic acid (Malonic acid) involves the interaction of malonic acid or its diesters with the carbonyl group of a ketone or an aldehyde.
This process is followed by a dehydration reaction.



BIOCHEMISTRY OF PROPANEDIOIC ACID (MALONIC ACID):
The calcium salt of Propanedioic acid (Malonic acid) occurs in high concentrations in beetroot.
Propanedioic acid (Malonic acid) exists in its normal state as white crystals.



ORGANIC SYNTHESIS OF PROPANEDIOIC ACID (MALONIC ACID):
A classical preparation of Propanedioic acid (Malonic acid) starts from acetic acid.
Propanedioic acid (Malonic acid) is chlorinated to chloroacetic acid.
Sodium carbonate generates the sodium salt which is then reacted with sodium cyanide to the cyano acetic acid salt in a nucleophilic substitution.
The nitrile group can be hydrolysed with sodium hydroxide to sodium malonate and acidification affords Propanedioic acid (Malonic acid).



ORGANIC REACTIOS OF PROPANEDIOIC ACID (MALONIC ACID):
In a well known reaction Propanedioic acid (Malonic acid) condenses with urea to barbituric acid.
Propanedioic acid (Malonic acid) is frequently used as an enolate in Knoevenagel condensations or condensed with acetone to form Meldrum's acid.
Propanedioic acid (Malonic acid)'s esters are also used for the -CH2COOH synthon in the malonic ester synthesis.



OCCURRENCE OF PROPANEDIOIC ACID (MALONIC ACID):
Propanedioic acid (Malonic acid) is an organic compound naturally found in some fruits.
Fruits produced in organic farming have greater concentrations of Propanedioic acid (Malonic acid) than those generated from conventional farming practices.

Propanedioic acid (Malonic acid) is often found in some citrus fruits and vegetables.
Propanedioic acid (Malonic acid) is a component of food items, it is present in animals, including humans.
The name of Propanedioic acid (Malonic acid) is derived from the Greek word Malon.

It means apple.
The ionized form of Propanedioic acid (Malonic acid) is malonate, along with its salts and esters.
Propanedioic acid (Malonic acid) occurs as a white crystal or crystalline powder in nature.



DID YOU KNOW:
Several food substances contain Propanedioic acid (Malonic acid), including:
● Red beetroots
● Corns
● Common beets
● Scarlet beans
● Cow’s milk
Its occurrence in food items makes Propanedioic acid (Malonic acid) a potential biomarker indicating the consumption of these foods.



HISTORY OF PROPANEDIOIC ACID (MALONIC ACID):
In 1858, Propanedioic acid (Malonic acid) was prepared for the first time by a French chemist –Victor Dessaignes.
He oxidized malic acid with potassium dichromate, which is a strong oxidizing agent.
Later Propanedioic acid (Malonic acid) was found to occur in some fruits viz citrus fruits.
Propanedioic acid (Malonic acid) can also be produced by fermenting glucose.



SIGNIFICANCE OF PROPANEDIOIC ACID (MALONIC ACID):
Propanedioic acid (Malonic acid) is an example of a competitive inhibitor.
Propanedioic acid (Malonic acid) functions in the ETS chain against succinate dehydrogenase in respiration.

Propanedioic acid (Malonic acid) is related to a deficiency of malonyl-CoA decarboxylase that leads to an inborn metabolism mistake.
It serves as a potential biomarker for tracking foods that contain Propanedioic acid (Malonic acid).
Propanedioic acid (Malonic acid) finds usage in various industries.



FORMULA OF PROPANEDIOIC ACID (MALONIC ACID):
The Propanedioic acid (Malonic acid) formula is C3H4O4.
Propanedioic acid (Malonic acid) is also called propanedioic acid or dicarboxymethane, and the formula is written as CH₂(COOH)₂.

So, the names of C3H4O4 are as follows:
*Malonic acid
*Propanedioic acid
*Carboxy Acetic acid
*Dicarboxymethane
*Methane dicarboxylic acid
*Dicarboxylate
*Dicarboxylic acid
*1,3-Propanedioic acid
*Methane dicarbonic acid
*Propane-1,3-dioic acid



STRUCTURE OF PROPANEDIOIC ACID (MALONIC ACID):
The structure of Propanedioic acid (Malonic acid) is as follows:
*Propanedioic acid (Malonic acid) is diprotic.
*Propanedioic acid (Malonic acid) can donate two protons per molecule.



CHEMICALS CLOSELY RELATED TO PROPANEDIOIC ACID (MALONIC ACID):
● Difluoro Malonic acid:
It is the fluorinated version of Propanedioic acid (Malonic acid).

● Malonate includes esters and salts of malonic acids, such as:
*Disodium malonate
*Diethyl malonate
*Malonyl-CoA
*Dimethyl malonate



PREPARATION OF PROPANEDIOIC ACID (MALONIC ACID):
Propanedioic acid (Malonic acid) can be prepared with chloroacetic acid (also called mono chloroacetic acid).
Sodium carbonate gives sodium salt.
The salt reacts with sodium cyanide.

Nucleophilic substitution reaction gives rise to cyanoacetic acid salt.
The nitrile group is hydrolyzed with NaOH to produce sodium malonate.
The acidification of sodium malonate gives Propanedioic acid (Malonic acid).

*Industrial Preparation:
Propanedioic acid (Malonic acid) can also be produced by hydrolyzing diethyl malonate or dimethyl malonate.



PHYSICAL and CHEMICAL PROPERTIES of PROPANEDIOIC ACID (MALONIC ACID):
Melting point: 132-135 °C (dec.) (lit.)
Boiling point: 140℃(decomposition)
Density: 1.619 g/cm3 at 25 °C
vapor pressure: 0-0.2Pa at 25℃
refractive index: 1.4780
Flash point: 157°C
storage temp.: Sealed in dry,Room Temperature
solubility: 1 M NaOH: soluble100mg/mL, clear to slightly hazy, colorless to faintly yellow
form: Liquid
pka: 2.83(at 25℃)
color: White
PH: 3.17(1 mM solution);2.5(10 mM solution);1.94(100 mM solution)
Water Solubility: 1400 g/L (20 ºC)

Merck: 14,5710
BRN: 1751370
Stability: Stable.
Incompatible with oxidizing agents, reducing agents, bases.
InChIKey: OFOBLEOULBTSOW-UHFFFAOYSA-N
LogP: -0.81
CAS DataBase Reference 141-82-2(CAS DataBase Reference)
EWG's Food Scores: 1
FDA UNII: 9KX7ZMG0MK
NIST Chemistry Reference: Malonic acid(141-82-2)
EPA Substance Registry System: Propanedioic acid (141-82-2)
Physical Appearance: A solid
Storage: Store at -20°C
M.Wt: 104.06
Cas No.: 141-82-2

Formula: C3H4O4
Solubility: ≥10.4 mg/mL in DMSO; ≥104 mg/mL in H2O; ≥119.8 mg/mL in EtOH
Chemical Name: malonic acid
Canonical SMILES: O=C(O)CC(O)=O
Shipping Condition: Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
CAS Number: 141-82-2
Molecular Weight: 104.06
Beilstein: 1751370
MDL number: MFCD00002707
Molecular Weight: 104.06 g/mol
XLogP3: -0.8
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2

Exact Mass: 104.01095860 g/mol
Monoisotopic Mass: 104.01095860 g/mol
Topological Polar Surface Area: 74.6Ų
Heavy Atom Count: 7
Formal Charge: 0
Complexity: 83.1
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Physical state: powder
Color: white
Odor: odorless

Melting point/freezing point:
Melting point: >= 135 °C
Initial boiling point and boiling range: 215 °C at 18,66 hPa (decomposition)
Flammability (solid, gas): The product is not flammable.
Upper/lower flammability or explosive limits: No data available
Flash point: 157 °C - c.c.
Autoignition temperature: No data available
Decomposition temperature: > 140 °C
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility 766 g/l at 20 °C

Partition coefficient:
n-octanol/water:
log Pow: -0,81 - Bioaccumulation is not expected.
Vapor pressure: 0,002 hPa at 25 °C
Density: 1,6 g/cm3
Relative density: 1,03 at 20 °C
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
CAS Number: 141-82-2
InChI: InChI=1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7) check
Key: OFOBLEOULBTSOW-UHFFFAOYSA-N
InChI=1/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)
Key: OFOBLEOULBTSOW-UHFFFAOYAJ

SMILES: O=C(O)CC(O)=O
C(C(=O)O)C(=O)O
Chemical formula: C3H4O4
Molar mass: 104.061 g•mol−1
Density: 1.619 g/cm3
Melting point: 135 to 137 °C (275 to 279 °F; 408 to 410 K) (decomposes)
Boiling point: decomposes
Solubility in water: 763 g/L
Acidity (pKa): pKa1 = 2.83
pKa2 = 5.69
Magnetic susceptibility (χ): -46.3•10−6 cm3/mol
Chemical Formula: C3H4O4
Average Molecular Weight: 104.0615
Monoisotopic Molecular Weight: 104.010958616
IUPAC Name: propanedioic acid
Traditional Name: malonic acid

CAS Registry Number: 141-82-2
SMILES: OC(=O)CC(O)=O
InChI Identifier: InChI=1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)
InChI Key: OFOBLEOULBTSOW-UHFFFAOYSA-N
Molecular Weight: 104.06100
Exact Mass: 104.06
EC Number: 205-503-0
UNII: 9KX7ZMG0MK
ICSC Number: 1085
NSC Number: 8124
DSSTox ID: DTXSID7021659
Color/Form: White crystals|Crystalline powder
Colorless hygroscopic solid which sublimes in vacuum
HScode: 2917190090
PSA: 74.60000
XLogP3: -0.8
Appearance: Malonic acid appears as white crystals or crystalline powder.
Sublimes in vacuum.

Density: 1.6 g/cm3
Melting Point: 135 °C (decomp)
Boiling Point: 215 °C @ Press: 14 Torr
Flash Point: 201.9ºC
Refractive Index: 1.479
Water Solubility: H2O: 1400 g/L (20 ºC)
Storage Conditions: Store at RT.
Vapor Pressure: 4.66E-07mmHg at 25°C
PKA: 2.85(at 25 °C)
Dissociation Constants: 2.85 (at 25 °C)|pKa1 = 2.8, pKa2 = 5.7 at 25 °C
Experimental Properties:
Enthalpy of Sublimation: 72.7 kJ/mol at 306 deg K, 108.0 kJ/mol at 348 deg K

Henry's Law constant = 4.8X10-13 atm-cu m/mole at 23 °C
(estimated from vapor pressure and water solubility)
Hydroxyl radical reaction rate constant = 1.6X10-12 cu-cm/molc sec at 25 °C (est)
Air and Water Reactions: Water soluble.
Reactive Group: Acids, Carboxylic
Heat of Combustion: Molar heat of combustion: 864 kJ/mol
Heat of Vaporization: 92 kJ/mol
Critical Temperature & Pressure:
Critical temperature: 805 K (estimated);
critical pressure: 5640 kPa (estimated)
CAS: 141-82-2
Molecular Formula: C3H4O4
Molecular weight: 104.06
EINECS: 205-503-0

Purity: ≥99%
Appearance: White crystal powder
Melting point: 132-135 °C (dec.) (lit.)
Boiling point: 140ºC(decomposition)
Density: 1.619 g/cm3 at 25 °C
Refractive index: 1.478
Flash Point: 157°C
Storage condition: Sealed in dry,Room Temperature
Solubility : 1 M NaOH: soluble100mg/mL, clear to slightly hazy, colorless to faintly yellow
Pka: 2.83(at 25ºC)
Stability: Stable.
Incompatible with oxidizing agents, reducing agents, bases.
HS Code: 29171910

PH: 3.17(1 mM solution);2.5(10 mM solution);
1.94(100 mM solution)
MDL: MFCD00002707
Water Solubility: 1400 g/L (20 ºC)
Vapor Presure: 0-0.2Pa at 25ºC
Physical and Chemical Properties:
Character: white crystal.
soluble in water, soluble in ethanol and ether, pyridine.
Color: White
Formula Weight: 104.1
Percent Purity: 0.99
Physical Form: Powder
Chemical Name or Material: Malonic acid
Melting point: 132-135 °C (dec.) (lit.)
Boiling point: 140℃(decomposition)

Density: 1.619 g/cm3 at 25 °C
vapor pressure: 0-0.2Pa at 25℃
refractive index: 1.4780
Flash point: 157°C
storage temp.: Sealed in dry,Room Temperature
solubility: 1 M NaOH: soluble100mg/mL, clear to slightly hazy, colorless to faintly yellow
form: Liquid
pka: 2.83(at 25℃)
color: White
PH: 3.17(1 mM solution);2.5(10 mM solution);1.94(100 mM solution)
Water Solubility: 1400 g/L (20 ºC)
Merck: 14,5710
BRN: 1751370
Stability: Stable.
Incompatible with oxidizing agents, reducing agents, bases.
InChIKey: OFOBLEOULBTSOW-UHFFFAOYSA-N

LogP: -0.81
CAS DataBase Reference: 141-82-2(CAS DataBase Reference)
EWG's Food Scores: 1
FDA UNII: 9KX7ZMG0MK
NIST Chemistry Reference: Malonic acid(141-82-2)
EPA Substance Registry System: Propanedioic acid (141-82-2)
Molecular Weight: 104.06 g/mol
XLogP3: -0.8
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 104.01095860 g/mol
Monoisotopic Mass: 104.01095860 g/mol
Topological Polar Surface Area: 74.6Ų

Heavy Atom Count: 7
Formal Charge: 0
Complexity: 83.1
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical formula: C3H4O4
Molar mass: 104.061 g•mol−1
Density: 1.619 g/cm3
Melting point: 135 to 137 °C (275 to 279 °F; 408 to 410 K) (decomposes)
Boiling point: decomposes
Solubility in water: 763 g/L
Acidity (pKa): pKa1 = 2.83

pKa2 = 5.69
Magnetic susceptibility (χ): -46.3•10−6 cm3/mol
Solubility: Dissolves in alcohol, pyridine, and ether.
Molecular Wt/ Molar Mass: 104.06 g/mol
Density: 1.619 g/cm³
Boiling Point: Decomposes
Melting Point: 135 to 137°C
Nature: Acidic
Color: White
Stability: Usually stable under recommended conditions
Molar heat of combustion: 864 kJ/mol
The heat of vaporization: 92 kJ/mol
It does not have a chiral center.
So, it doesn’t exhibit optical isomerism.
It is a hygroscopic solid that sublimes in a vacuum.
Chemical Formula: C3H4O4
Average Molecular Weight: 104.0615
Monoisotopic Molecular Weight: 104.010958616

IUPAC Name: propanedioic acid
Traditional Name: malonic acid
CAS Registry Number: 141-82-2
SMILES: OC(=O)CC(O)=O
InChI Identifier: InChI=1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)
InChI Key: OFOBLEOULBTSOW-UHFFFAOYSA-N
CAS number: 141-82-2
Weight Average: 104.0615
Monoisotopic: 104.010958616
InChI Key: OFOBLEOULBTSOW-UHFFFAOYSA-N
InChI: InChI=1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)
IUPAC Name: propanedioic acid
Traditional IUPAC Name: malonic acid
Chemical Formula: C3H4O4
SMILES: OC(=O)CC(O)=O

Water Solubility: 197 g/L
logP: -0.6
logP: -0.33
logS: 0.28
pKa (Strongest Acidic): 2.43
Physiological Charge: -2
Hydrogen Acceptor Count: 4
Hydrogen Donor Count: 2
Polar Surface Area: 74.6 Ų
Rotatable Bond Count: 2
Refractivity: 18.99 m³•mol⁻¹
Polarizability: 8.13 ų
Number of Rings: 0
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: Yes
Veber's Rule: Yes
MDDR-like Rule: Yes



FIRST AID MEASURES of PROPANEDIOIC ACID (MALONIC ACID):
-Description of first-aid measures
*General advice
Show this material safety data sheet to the doctor in attendance.
*If inhaled
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed
No data available



ACCIDENTAL RELEASE MEASURES of PROPANEDIOIC ACID (MALONIC ACID):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of PROPANEDIOIC ACID (MALONIC ACID):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of PROPANEDIOIC ACID (MALONIC ACID):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P2
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of PROPANEDIOIC ACID (MALONIC ACID):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
*Storage class:
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of PROPANEDIOIC ACID (MALONIC ACID):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .


Propargyl Alcohol
2-Propyn-1-ol; Acetyleneylcarbinol; Propyn-1-ol; Propargyl alcohol; 1-Propyne-3-ol; 2-Propynyl alcohol; Ethynylcarbinol; Ethynyl methanol; Prop-2-yn-1-ol; propiolic alcohol; Prop-2-in-1-ol; hydroxymethylacetylene; Acetylene carbinol CAS NO:107-19-7
PROPARGYL ALCOHOL
DESCRIPTION:

Propargyl alcohol, or 2-propyn-1-ol, is an organic compound with the formula C3H4O.
Propargyl alcohol is the simplest stable alcohol containing an alkyne functional group.
Propargyl alcohol is a colorless viscous liquid that is miscible with water and most polar organic solvents.

CAS Number: 107-19-7
EC Number: 203-471-2
IUPAC name: Prop-2-yn-1-ol

CHEMICAL AND PHYSICAL PROPERTIES OF PROPARGYL ALCOHOL:
Chemical formula: C3H4O
Molar mass: 56.064 g•mol−1
Appearance: Colorless to straw-colored liquid
Odor: geranium-like
Density : 0.9715 g/cm3
Melting point: −51 to −48 °C (−60 to −54 °F; 222 to 225 K)
Boiling point: 114 to 115 °C (237 to 239 °F; 387 to 388 K)
Solubility in water: miscible
Vapor pressure : 12 mmHg (20 °C)
Linear Formula: HC≡CCH2OH
CAS Number: 107-19-7
Molecular Weight: 56.06
Beilstein: 506003
EC Number: 203-471-2
MDL number: MFCD00002912
PubChem Substance ID: 24898591
vapor density: 1.93 (vs air)
Quality Level: 100
vapor pressure: 11.6 mmHg ( 20 °C)
Assay: 99%
refractive index: n20/D 1.432 (lit.)
bp: 114-115 °C (lit.)
Mp: −53 °C (lit.)
Density: 0.963 g/mL at 25 °C (lit.)
storage temp.: 2-8°C
Molecular Weight 56.06
XLogP3 -0.4
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 1
Rotatable Bond Count 0
Exact Mass 56.026214747
Monoisotopic Mass 56.026214747
Topological Polar Surface Area 20.2 Ų
Heavy Atom Count 4
Formal Charge 0
Complexity 38.5
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
Appearance (Clarity) Clear
Appearance (Colour) Colourless
Appearance (Form) Liquid
Assay (GC) min. 99%
Density (g/ml) @ 20°C 0.945-0.950
Refractive Index (20°C) 1.430-1.432
Boiling Range 112-115°C
Molecular Formula : C3H4O
Molecular Weight : 56.06
Storage : Room Temperature
Shelf Life : 60 Months
Appearance: colorless to pale yellow clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.96300 @ 25.00 °C.
Boiling Point: 113.60 °C. @ 760.00 mm Hg
Vapor Pressure: 10.556000 mmHg @ 25.00 °C. (est)
Flash Point: 97.00 °F. TCC ( 36.11 °C. )
logP (o/w): -0.380

Propargyl alcohol appears as a clear colorless liquid with a geranium-like odor.
The Flash point of Propargyl alcohol is 97 °F.
Vapors of Propargyl alcohol are heavier than air.

Propargyl alcohol is Used to make other chemicals, as a corrosion inhibitor and a soil fumigant.
Prop-2-yn-1-ol is a terminal acetylenic compound that is prop-2-yne substituted by a hydroxy group at position 1.
Propargyl alcohol has a role as a Saccharomyces cerevisiae metabolite and an antifungal agent.

Propargyl alcohol is a terminal acetylenic compound, a volatile organic compound and a propynol.
2-Propyn-1-ol is a metabolite found in or produced by Saccharomyces cerevisiae.

Propargyl alcohol is an organic compound with two reactive sides and is used as a chemical intermediate or as a corrosion inhibitor component in the industrial as well as profesional area.
Therefore, Propargyl alcohol can be used as a versatile intermediate, i.e. for the synthesis of antibiotics, pesticides, as a precursor to a fungicide (IPBC), as iron dissolution inhibitor in mineral acids, as corrosion inhibitor during oil well stimulation and as electroplating bath additive.

Propargyl alcohol is a solvent stabilizer that is useful as an intermediate in organic synthesis, an electroplating brightener additive.
Propargyl alcohol is useful 3-carbon fragment in acetylene coupling reactions
Propargyl alcohol undergoes Pd-catalyzed O-coupling with alcohols to give the corresponding 1-methoxyallyl ethers.
Solubility: Fully miscible in water.

Propargyl alcohol is a propargyl compound that has been shown to bind to the hydroxyl group of an allyl carbonate.
Propargyl alcohol has been shown to have carcinogenic effects in rats, but not in mice.
Propargyl alcohol is also a good electrochemical agent for the synthesis of 1,4-dioxane.

Propargyl alcohol reacts with an inorganic acid and forms a catalyst for the transfer reactions of organic compounds.
Propargyl alcohol induces enzymes and is used as an asymmetric synthesis reagent in human serum.




REACTIONS AND APPLICATIONS OF PROPARGYL ALCOHOL:
Propargyl alcohol polymerizes with heating or treatment with base.
Propargyl alcohol is used as a corrosion inhibitor, a metal complex solution, a solvent stabilizer and an electroplating brightener additive.
Propargyl alcohol is also used as an intermediate in organic synthesis.

Secondary and tertiary substituted propargylic alcohols undergo catalyzed rearrangement reactions to form α,β-unsaturated carbonyl compounds via the Meyer–Schuster rearrangement and others.
Propargyl alcohol can be oxidized to propynal[4] or propargylic acid.

As an indication of the electronegativity of an sp carbon, propargyl alcohol is significantly more acidic (pKa = 13.6) compared to its sp2-containing analog allyl alcohol (pKa = 15.5), which is in turn more acidic than the fully saturated (sp3 carbons only) n-propyl alcohol (pKa = 16.1).


APPLICATIONS OF PROPARGYL ALCOHOL:
Propargyl alcohol has been used as a key starting material in the [4+2] cycloisomerization mediated synthesis of various phthalide derivatives.
Propargyl alcohol can also be used to synthesize:

A variety of regioselective furan-3-carboxamides by reacting with 3-oxo amides using Ag2CO3 as a promoter.
β-oxopropyl esters by reacting with carboxylic acids in the presence of (arene) (phosphine)ruthenium(II) complex as a catalyst

Propargyl alcohol is a solvent stabilizer that is useful as an intermediate in organic synthesis, an electroplating brightener additive.
Propargyl alcohol is useful 3-carbon fragment in acetylene coupling reactions.
Propargyl alcohol undergoes Pd-catalyzed O-coupling with alcohols to give the corresponding 1-methoxyallyl ethers.

PREPARATION OF PROPARGYL ALCOHOL:
Propargyl alcohol is produced by the copper-catalysed addition of formaldehyde to acetylene as a by-product of the industrial synthesis of but-2-yne-1,4-diol.
Propargyl alcohol can also be prepared by dehydrochlorination of 3-chloro-2-propen-1-ol by NaOH



SAFETY INFORMATION ABOUT PROPARGYL ALCOHOL:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.



SYNONYMS OF PROPARGYL ALCOHOL:
1-propyn-3-ol
2-propyn-1-ol
propargyl alcohol
propargyl alcohol, lithium salt
propargyl alcohol, sodium salt
PROPARGYL ALCOHOL
Prop-2-yn-1-ol
2-Propyn-1-ol
107-19-7
2-Propynyl alcohol
Ethynylcarbinol
1-Propyn-3-ol
Ethynyl carbinol
Methanol, ethynyl-
Propynyl alcohol
2-Propynol
3-Propynol
1-Hydroxy-2-propyne
3-Hydroxy-1-propyne
Acetylenylcarbinol
Acetylene carbinol
Agrisynth PA
Propiolic alcohol
RCRA waste number P102
prop-2-yne-1-ol
Prop-2-in-1-ol
propargylalcohol
1-Propyn-3-yl alcohol
NSC 8804
DTXSID5021883
CHEBI:28905
E920VF499L
NSC-8804
Propargyl alcohol [NA1986] [Flammable liquid]
30306-19-5
2-propyne-1-ol
CCRIS 6781
HSDB 6054
EINECS 203-471-2
NA1986
RCRA waste no. P102
BRN 0506003
ethynylmethanol
UNII-E920VF499L
AI3-24359
prop-2-ynol
propyn-3-ol
1-Propyne-3-ol
2-propyn-1 ol
MFCD00002912
prop-2-yn-I-ol
prop-1-yn-3-ol
Propargyl alcohol, 99%
bmse000363
EC 203-471-2
HC.$.CCH2OH
WLN: Q2UU1
4-01-00-02214 (Beilstein Handbook Reference)
PROPARGYL ALCOHOL [MI]
DTXCID301883
CHEMBL1563026
PROPARGYL ALCOHOL [HSDB]
NSC8804
ZINC895974
Tox21_200976
BBL011350
STL146440
AKOS000118737
NA 1986
NCGC00091559-01
NCGC00091559-02
NCGC00258529-01
BP-30161
CAS-107-19-7
P0536
EN300-19326
C05986
Q903345
Q-201629
F0001-0140



PROPARGYL ALCOHOL (PROPYNOL)
Propargyl Alcohol (propynol), or 2-propyn-1-ol, is an organic compound with the formula C3H4O.
Propargyl Alcohol (propynol) is the simplest and most stable alcohol containing an alkyne functional group.
Propargyl Alcohol (propynol) is a colorless, viscous liquid that is miscible with water and most polar organic solvents.


CAS Number: 107-19-7
EC Number: 203-471-2
MDL number: MFCD00002912
Linear Formula: HC≡CCH2OH
Chemical formula: C3H4O


Propargyl Alcohol (propynol) other names 3-hydroxy-1-propyne; 2-Propynol.
Propargyl Alcohol (propynol) is a colorless liquid with a geranium-like odor.
Propargyl Alcohol (propynol), or 2-propyn-1-ol, is an organic compound with the formula C3H4O.


Propargyl Alcohol (propynol) is the simplest stable alcohol containing an alkyne functional group.
Propargyl Alcohol (propynol) is a colorless viscous liquid that is miscible with water and most polar organic solvents.
Propargyl Alcohol (propynol) is a clear colourless to slightly yellow liquid


Propargyl Alcohol (propynol) is a colorless liquid with a geranium-like odor.
Propargyl Alcohol (propynol) is a terminal acetylenic compound that is prop-2-yne substituted by a hydroxy group at position 1.
Propargyl Alcohol (propynol), or 2-propyn-1-ol, is an organic compound with the formula C3H4O.


Propargyl Alcohol (propynol) is the simplest stable alcohol containing an alkyne functional group.
Propargyl Alcohol (propynol) is a colorless viscous liquid that is miscible with water and most polar organic solvents.
Propargyl Alcohol (propynol), or 2-propyn-1-ol, is an organic compound with the formula C3H4O.


Propargyl Alcohol (propynol) is the simplest and most stable alcohol containing an alkyne functional group.
Propargyl Alcohol (propynol) is a colorless, viscous liquid that is miscible with water and most polar organic solvents.
Propargyl Alcohol (propynol) is a dark liquid with a "fishlike" odor. Propargyl Alcohol (propynol) is less dense than water.


The flash point of Propargyl Alcohol (propynol) is 90°F.
The boiling point of Propargyl Alcohol (propynol) is 239°F.
Propargyl Alcohol (propynol) is soluble in water.


Propargyl Alcohol (propynol), known by various names such as propynol, prop-2-yn-1-ol, or 2-propyn-1-ol, is an organic compound that finds wide-ranging applications in the scientific and industrial domains.
Propargyl Alcohol (propynol) is a colorless and volatile liquid characterized by a sweet and pungent odor.


As a three-carbon alkyl alcohol, Propargyl Alcohol (propynol)'s molecular formula is C3H4O.
Propargyl Alcohol (propynol) is a solvent stabilizer that is useful as an intermediate in organic synthesis, an electroplating brightener additive.
Propargyl Alcohol (propynol) is useful 3-carbon fragment in acetylene coupling reactions.


Propargyl Alcohol (propynol) undergoes Pd-catalyzed O-coupling with alcohols to give the corresponding 1-methoxyallyl ethers.
Propargyl Alcohol (propynol) is colorless to straw-colored liquid with a mild, geranium odor.
Propargyl Alcohol (propynol) appears as a clear colorless liquid with a geranium-like odor.


Propargyl Alcohol (propynol) is a terminal acetylenic compound, a volatile organic compound and a propynol.
Propargyl Alcohol (propynol) is miscible with benzene, chloroform, ethanol, 1,2-dichloroethane, ether, acetone, dioxane, tetrahydrofuran, pyridine; moderately sol in carbon tetrachloride.


Propargyl Alcohol (propynol) is miscible with water
Propargyl Alcohol (propynol) is solubility in water: miscible
Propargyl Alcohol (propynol), or 2-propyn-1-ol, is an organic compound with the formula C3H4O.


Propargyl Alcohol (propynol) is the simplest and most stable alcohol containing an alkyne functional group.
Propargyl Alcohol (propynol) is a colorless, viscous liquid that is miscible with water and most polar organic solvents.
Propargyl Alcohol (propynol), or 2-propyn-1-ol, is an organic compound with the formula C3H4O.


Propargyl Alcohol (propynol) is the simplest and most stable alcohol containing an alkyne functional group.
Propargyl Alcohol (propynol) is a colorless, viscous liquid that is miscible with water and most polar organic solvents.
Propargyl Alcohol (propynol) is a metabolite found in or produced by Saccharomyces cerevisiae.


Propargyl Alcohol (propynol) (13C3, 99%) is a carbon-13 labeled compound that is often used as an intermediate in organic synthesis.
Propargyl Alcohol (propynol) is fully miscible in water.
Propargyl Alcohol (propynol) is a solvent stabilizer that is useful as an intermediate in organic synthesis, an electroplating brightener additive.


Propargyl Alcohol (propynol) is useful 3-carbon fragment in acetylene coupling reactions.
Propargyl Alcohol (propynol) undergoes Pd-catalyzed O-coupling with alcohols to give the corresponding 1-methoxyallyl ethers.
Propargyl Alcohol (propynol) appears as a clear colorless liquid with a geranium-like odor.


The flash point of Propargyl Alcohol (propynol) is 97 °F.
Propargyl Alcohol (propynol)'s vapors are heavier than air.
Propargyl Alcohol (propynol) is a terminal acetylenic compound that is prop-2-yne substituted by a hydroxy group at position 1.


Propargyl Alcohol (propynol) has a role as a Saccharomyces cerevisiae metabolite and an antifungal agent.
Propargyl Alcohol (propynol) is a terminal acetylenic compound, a volatile organic compound and a propynol.



USES and APPLICATIONS of PROPARGYL ALCOHOL (PROPYNOL):
Propargyl Alcohol (propynol) uses and applications include: Corrosion inhibitor for oil-well acidizing, electroplating baths; inhibits attack of mineral acids on steel; prevents hydrogen embrittlement of steel; metal picklingplating; electroplating brightener additive; stabilizer for solvents, chlorinated hydrocarbon formulations; polishing agent in galvanotechnics; soil fumigant; solvent for cellulose acetate; chemical intermediate in organic synthesis, production of alkaloids, antibiotics, vitamins, pharmaceuticals, pesticides, biocides; laboratory reagent.


Propargyl Alcohol (propynol) is used as an rust remover, chemical intermediate, corrosion inhibitor, solvent, stabilizer, etc.
Propargyl Alcohol (propynol) is used Organic synthesis intermediates, solvents, stabilizers of chlorinated hydrocarbons.
Propargyl Alcohol (propynol) is used an hydrochloric acid and other industrial corrosion inhibitors in acidizing and fracturing process of oil and gas wells.


Propargyl Alcohol (propynol) can be used as a corrosion inhibitor separately.
Propargyl Alcohol (propynol) is used as a corrosion inhibitor alone, and it is better to mix with the substances which have synergistic effect to obtain higher corrosion inhibition efficiency.


Propargyl Alcohol (propynol) is used anticorrosive agent, manufacturing of organic products.
Propargyl Alcohol (propynol)’s widely used in the production of medicines (sodium sulfonamides, fosfomycin, etc.) and pesticides (propargene).
Propargyl Alcohol (propynol) can be used as a drill pipe and tubing corrosion inhibitor in the petroleum industry.


Propargyl Alcohol (propynol) is used as an additive in the steel industry to prevent hydrogen embrittlement of steel, etc.
Propargyl Alcohol (propynol) is used Chemical intermediate, corrosion inhibitor, lab reagent, solvent stabilizer, prevents hydrogen embrittlement of steel, soil fumigant.


Propargyl Alcohol (propynol) is used to prevent the hydrogen embrittlement of steel; as a corrosion inhibitor, solvent stabilizer, soil fumigant, and chemical intermediate.
Propargyl Alcohol (propynol) is a solvent stabilizer that is useful as an intermediate in organic synthesis, an electroplating brightener additive.


Propargyl Alcohol (propynol) is useful 3-carbon fragment in acetylene coupling reactions.
Propargyl Alcohol (propynol) undergoes Pd-catalyzed O-coupling with alcohols to give the corresponding 1-methoxyallyl ethers.
Propargyl Alcohol (propynol) is used to make other chemicals.


Propargyl Alcohol (propynol) is used in metal plating and pickling and asa corrosion inhibitor of mild steel in mineral acids.
Propargyl Alcohol (propynol) also finds application in preventingthe hydrogen embrittling of mild steel inacids.
Propargyl Alcohol (propynol) is used as an intermediate for makingmiticide and sulfadiazine.


Propargyl Alcohol (propynol) serves as a valuable reagent in organic synthesis and as a solvent for diverse applications.
Furthermore, Propargyl Alcohol (propynol) functions as a catalyst in certain reactions and finds utility as a fuel additive.
The applications of Propargyl Alcohol (propynol) extend to numerous scientific research domains.


Propargyl Alcohol (propynol) plays a vital role in the synthesis of polymers such as poly(ethylene oxide) and poly(propylene oxide).
These polymers can possess a wide range of functional groups, such as esters, amides, and amines.
Due to its alkylating properties, Propargyl Alcohol (propynol) readily reacts with nucleophiles like amines and thiols.


Notably, Propargyl Alcohol (propynol) acts as an oxidizing agent capable of converting primary alcohols to aldehydes and secondary alcohols to ketones.
Moreover, Propargyl Alcohol (propynol) demonstrates the ability to oxidize sulfides into sulfoxides.
Propargyl Alcohol (propynol) is used as a corrosion inhibitor, a metal complex solution, a solvent stabilizer and an electroplating brightener additive.


Propargyl Alcohol (propynol) is also used as an intermediate in organic synthesis.
Propargyl Alcohol (propynol) is used to make other chemicals, as a corrosion inhibitor and a soil fumigant.
Propargyl Alcohol (propynol) is a terminal acetylenic compound that is prop-2-yne substituted by a hydroxy group at position 1.


Propargyl Alcohol (propynol) has a role as a Saccharomyces cerevisiae metabolite and an antifungal agent.
Propargyl Alcohol (propynol) is used to make other chemicals, as a corrosion inhibitor and a soil fumigant.
Propargyl Alcohol (propynol) is a solvent stabilizer that is useful as an intermediate in organic synthesis, an electroplating brightener additive.
Propargyl Alcohol (propynol) is used a solvent stabilizer.



PHYSICAL AND CHEMICAL PROPERTIES OF PROPARGYL ALCOHOL (PROPYNOL):
Propargyl Alcohol (propynol) is a colorless, volatile liquid with irritating odor.
Propargyl Alcohol (propynol) is easy to yellow especially when exposed to light.
With water, benzene, chloroform, 1, 2-dichloroethane, ethyl ether, ethanol, acetone, dioxane, Tetrahydrofuran, pyridine miscible, partially soluble in carbon tetrachloride, but Propargyl Alcohol (propynol) is insoluble in aliphatic hydrocarbons.



PURIFICATION METHODS OF PROPARGYL ALCOHOL (PROPYNOL):
The commercial material contains a stabiliser.
An aqueous solution of Propargyl Alcohol (propynol) can be concentrated by azeotropic distillation with butanol or butyl acetate.
Dry it with K2CO3 and distil it under reduced pressure, in the presence of about 1% succinic acid, through a glass helices-packed column.



REACTIONS AND APPLICATIONS OF PROPARGYL ALCOHOL (PROPYNOL):
Propargyl Alcohol (propynol) is polymerized by heating or base treatment.
Propargyl Alcohol (propynol) is used as corrosion inhibitor, metal complex solution, solvent stabilizer, electroplating brightener additive.
Propargyl Alcohol (propynol) is also used as an intermediate in organic synthesis.

Secondary and tertiary substituted Propargyl Alcohol (propynol)s undergo catalyzed rearrangement reactions to form α,β-unsaturated carbonyl compounds such as via the Mayer-Schuster rearrangement.
This can be oxidized to propinalic acid or propargylic acid.
As an indicator of the electronegativity of the sp carbon, Propargyl Alcohol (propynol) is significantly more acidic (pKa = 13.6) compared to the sp2-containing analogue allyl alcohol (pKa = 15.5) and more acidic than the fully saturated (sp3 carbon). . only) n-propyl alcohol (pKa = 16.1).



PREPARATION OF PROPARGYL ALCOHOL (PROPYNOL):
Propargyl Alcohol (propynol) is produced by the copper-catalyzed addition of formaldehyde to acetylene as a by-product of the industrial synthesis of but-2-yne-1,4-diol.
Propargyl Alcohol (propynol) can also be prepared by dehydrochlorination of 3-chloro-2-propen-1-ol with NaOH.



PRODUCTION METHODS OF PROPARGYL ALCOHOL (PROPYNOL):
Propargyl Alcohol (propynol) is the major commercially available acetylenic primary alcohol.
Propargyl Alcohol (propynol) is a byproduct of butynediol production.
In the usual high-pressure butynediol process, about 5% of the product is Propargyl Alcohol (propynol).
Some processes give higher proportions of Propargyl Alcohol (propynol).



REACTIVITY PROFILE OF PROPARGYL ALCOHOL (PROPYNOL):
Propargyl Alcohol (propynol), FATTY ACID DERIVED AMINES is an aminoalcohol mixture.
Amines are chemical bases.
They neutralize acids to form salts plus water.

These acid-base reactions are exothermic.
The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base.
Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.

Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
When phosphorus pentaoxide is added to Propargyl Alcohol (propynol) caused ignition.
Acetyl bromide reacts violently with alcohols or water.
Mixtures of alcohols with concentrated sulfuric acid and strong hydrogen peroxide can cause explosions.

Example: An explosion will occur if dimethylbenzylcarbinol is added to 90% hydrogen peroxide then acidified with concentrated sulfuric acid.
Mixtures of ethyl alcohol with concentrated hydrogen peroxide form powerful explosives.
Mixtures of hydrogen peroxide and 1-phenyl-2-methyl propyl alcohol tend to explode if acidified with 70% sulfuric acid.

Alkyl hypochlorites are violently explosive.
They are readily obtained by reacting hypochlorous acid and alcohols either in aqueous solution or mixed aqueous-carbon tetrachloride solutions.
Chlorine plus alcohols would similarly yield alkyl hypochlorites.
They decompose in the cold and explode on exposure to sunlight or heat.

Tertiary hypochlorites are less unstable than secondary or primary hypochlorites.
Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents.
Such reactions in the absence of solvents often occur with explosive violence



PHYSICAL and CHEMICAL PROPERTIES of PROPARGYL ALCOHOL (PROPYNOL):
Chemical formula: C3H4O
Molar mass: 56.064 g·mol−1
Appearance: Colorless to straw-colored liquid
Odor: geranium-like
Density: 0.9715 g/cm3
Melting point: −51 to −48 °C (−60 to −54 °F; 222 to 225 K)
Boiling point: 114 to 115 °C (237 to 239 °F; 387 to 388 K)
Solubility in water: miscible
Vapor pressure: 12 mmHg (20 °C)
Molecular Weight: 56.06 g/mol
XLogP3: -0.4
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 0
Exact Mass: 56.026214747 g/mol
Monoisotopic Mass: 56.026214747 g/mol
Topological Polar Surface Area: 20.2Ų
Heavy Atom Count: 4
Formal Charge: 0
Complexity: 38.5
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1

Compound Is Canonicalized: Yes
Molecular Weight: 59.04 g/mol (Labeled)
Chemical Purity: 98%
Form: Individual
Concentration: Neat
Application(s): Synthetic Intermediates
Storage Temp: Store refrigerated (-5 °C to 5 °C). Protect from light.
CAS: 107-19-7
Molecular Formula: C3H4O
Molecular Weight (g/mol): 56.06
MDL Number: MFCD00002912
InChI Key: TVDSBUOJIPERQY-UHFFFAOYSA-N
Physical state: clear, liquid
Color: light yellow
Odor: No data available
Melting point/freezing point:
Melting point/range: -53 °C - lit.
Initial boiling point and boiling range: 114 - 115 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 33 °C - closed cup
Autoignition temperature: 365 °C at 1.013 hPa
Decomposition temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 1.000 g/l at 20 °C - soluble
Partition coefficient: n-octanol/water:
log Pow: -0,35 at 25 °C
Vapor pressure: 20,8 hPa at 25 °C
Density: 0,963 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Relative vapor density: 1,94 - (Air = 1.0)
CAS Number: 107-19-7
Molecular Formula: C₃H₄O
Appearance: Clear Colourless Liquid
Molecular Weight: 56.06
Storage: 20°C
Solubility: Chloroform, Ethyl Acetate
CAS No.: 107-19-7
Product Name: Propargyl Alcohol
Molecular Formula: C3H4O
CHCCH2OH
C3H4O

Molecular Weight: 56.06 g/mol
IUPAC Name: prop-2-yn-1-ol
Standard InChI: InChI=1S/C3H4O/c1-2-3-4/h1,4H,3H2
Standard InChIKey: TVDSBUOJIPERQY-UHFFFAOYSA-N
SMILES: C#CCO
Canonical SMILES: C#CCO
Boiling Point: 236.5 °F at 760 mm Hg 113.6 °C
114-115 °C at 760 mm Hg; 100 °C at 490.3 mm Hg;
70 °C at 147.6 mm Hg; 20 °C at 11.6 mm Hg
Colorform: Colorless liquid
Colorless to straw-colored liquid
Density: 0.9485 at 68 °F , 0.9715 at 20 °C/4 °C
Relative density (water = 1): 0.97, 0.9485, 0.97
Flash Point: 91 °F , 97 °F (36 °C) (Open cup) 33 °C c.c.
97°F (open cup) (oc) 97°F
Melting Point: -54 °F , -51.8 °C, -48 to -52 °C, -48 - -52 °C, -62°F
Vapor Density: Relative vapor density (air = 1): 1.93
Vapor Pressure: 12 mm Hg, 15.60 mmHg, 15.6 mm Hg at 25 °C
Vapor pressure, kPa at 20 °C: 1.54 12 mmHg
Melting point: -53 °C

Boiling point: 114-115 °C(lit.)
Density: 0.963 g/mL at 25 °C(lit.)
vapor density: 1.93 (vs air)
vapor pressure: 11.6 mm Hg ( 20 °C)
refractive index: n20/D 1.432(lit.)
Flash point: 97 °F
storage temp.: 2-8°C
solubility: soluble in Chloroform, Ethyl Acetate
form: Liquid
pka: 13.6(at 25℃)
color: Clear colorless to slightly yellow
Odor: at 100.00 %. geranium
Odor Type: floral
Water Solubility: miscible
Merck: 14,7809
BRN: 506003
LogP: -0.35 at 25℃
CAS DataBase Reference: 107-19-7(CAS DataBase Reference)
EWG's Food Scores: 1
FDA UNII: E920VF499L

NIST Chemistry Reference: 2-Propyn-1-ol(107-19-7)
EPA Substance Registry System: Propargyl alcohol (107-19-7)
ΔfG°: 60.63 kJ/mol
ΔfH°gas: 34.42 kJ/mol
ΔfusH°: 10.59 kJ/mol
ΔvapH°: 38.81 kJ/mol
IE: [10.45; 10.51] eV
log10WS: -0.14
logPoct/wat: -0.388
McVol: 50.400 ml/mol
Pc: 6239.25 kPa J
Inp: [546.00; 576.00]
I: [1320.00; 1357.00]
Tboil: [385.00; 387.50]K
Tc: 523.88 K
Tfus: 221.35 ± 0.30 K
Vc: 0.184 m3/kmol
Cp,gas: [81.35; 101.24] J/mol×K [350.34; 523.88]
ΔvapH: 42.00 kJ/mol 340.00
Pvap: [3.63e-03; 6558.50] kPa [221.35; 580.00]

CAS: 107-19-7
EINECS: 203-471-2
InChI: InChI=1/C3H4O/c1-2-3-4/h1,4H,3H2
Molecular Formula: C3H4O
Molar Mass: 56.06
Density: 0.963g/mLat 25°C(lit.)
Melting Point: -53 °C
Boling Point: 114-115°C(lit.)
Flash Point: 97°F
Water Solubility: miscible
Vapor Presure: 11.6 mm Hg ( 20 °C)
Vapor Density: 1.93 (vs air)
Appearance: Liquid
Color: Clear colorless to slightly yellow
Merck: 14,7809
BRN: 506003
pKa: 13.6(at 25℃)
Storage Condition: 2-8°C
Refractive Index: n20/D 1.432(lit.)
Molecular weight: 56.06
InChI: 1S/C3H4O/c1-2-3-4/h1,4H,3H2
InChIKey: TVDSBUOJIPERQY-UHFFFAOYSA-N
Atmospheric OH Rate Constant: 1.04E-11 cm3/molecule-sec
log P (octanol-water): -0.38
Boiling Point: 113.6 ° C
Water solubility: 1.00E+06 mg/L
Henry's Law Constant: 1.15E-06 atm-m3/mole

Vapor Pressure: 15.6 mm Hg
Melting Point: -5.18E+01 ° C
Molecular form: C3H4O
Appearance: NA
Mol. Weight: 56.06
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: NA
Density: 0.9±0.1 g/cm3
Boiling Point: 113.6±8.0 °C at 760 mmHg
Melting Point: -53 °C
Molecular Formula: C3H4O
Molecular Weight: 56.063
Flash Point: 36.1±0.0 °C
Exact Mass: 56.026215
PSA: 20.23000
LogP: -0.38
Vapour density: 1.93 (vs air)
Vapour Pressure: 10.6±0.4 mmHg at 25°C
Index of Refraction: 1.430
Water Solubility: miscible



FIRST AID MEASURES of PROPARGYL ALCOHOL (PROPYNOL):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of PROPARGYL ALCOHOL (PROPYNOL):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of PROPARGYL ALCOHOL (PROPYNOL):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of PROPARGYL ALCOHOL (PROPYNOL):
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles.
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 60 min
*Body Protection:
Flame retardant antistatic protective clothing.
*Respiratory protection
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of PROPARGYL ALCOHOL (PROPYNOL):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Advice on protection against fire and explosion:
Take precautionary measures against static discharge.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Keep away from heat and sources of ignition.
Keep locked up or in an area accessible only to qualified or authorized persons.
*Storage stability:
Recommended storage temperature: 2 - 8 °C



STABILITY and REACTIVITY of PROPARGYL ALCOHOL (PROPYNOL):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



SYNONYMS:
Prop-2-yn-1-ol
propynol, 2-propynol, 2-propyn-1-ol, hydroxymethylacetylene.
PROPARGYL ALCOHOL
Prop-2-yn-1-ol
2-Propyn-1-ol
107-19-7
2-Propynyl alcohol
Ethynylcarbinol
1-Propyn-3-ol
Ethynyl carbinol
Methanol, ethynyl-
Propynyl alcohol
2-Propynol
3-Propynol
1-Hydroxy-2-propyne
3-Hydroxy-1-propyne
Acetylenylcarbinol
Acetylene carbinol
Agrisynth PA
Propiolic alcohol
RCRA waste number P102
prop-2-yne-1-ol
Prop-2-in-1-ol
propargylalcohol
1-Propyn-3-yl alcohol
NSC 8804
DTXSID5021883
CHEBI:28905
E920VF499L
NSC-8804
Propargyl alcohol [NA1986]
2-propyne-1-ol
CCRIS 6781
HSDB 6054
EINECS 203-471-2
NA1986
RCRA waste no. P102
BRN 0506003
ethynylmethanol
UNII-E920VF499L
AI3-24359
prop-2-ynol
propyn-3-ol
1-Propyne-3-ol
2-propyn-1 ol
MFCD00002912
prop-2-yn-I-ol
prop-1-yn-3-ol
Propargyl alcohol, 99%
bmse000363
EC 203-471-2
HC.$.CCH2OH
WLN: Q2UU1
4-01-00-02214 (Beilstein Handbook Reference)
PROPARGYL ALCOHOL [MI]
DTXCID301883
CHEMBL1563026
PROPARGYL ALCOHOL [HSDB]
NSC8804
Tox21_200976
BBL011350
STL146440
AKOS000118737
NA 1986
NCGC00091559-01
NCGC00091559-02
NCGC00258529-01
BP-30161
CAS-107-19-7
P0536
EN300-19326
C05986
InChI=1/C3H4O/c1-2-3-4/h1,4H,3H
Q903345
Q-201629
F0001-0140
2-Propyn-1-ol-1,2,3-13C3
2-Propyn-1-ol
1-Hydroxy-2-propyne
1-Propyn-3-ol
1-Propyn-3-yl alcohol
2-Propynol
2-Propynyl alcohol
3-Hydroxy-1-propyne
3-Hydroxypropyne
3-Propynol
Ethynylcarbinol
Hydroxymethylacetylene
Propiolic alcohol
Propynyl alcohol
2-Propyn-1-ol
Ethynyl carbinol
Propynyl alcohol
1-Hydroxy-2-propyne
1-Propyn-3-ol
2-Propynol
2-Propynyl alcohol
3-Hydroxy-1-propyne
1-Propyne-3-ol
3-Propynol
prop-2-yn-1-ol
Methanol, ethynyl-
Rcra waste number P102
HC≡CCH2OH
1-Propyn-3-yl alcohol
NSC 8804
2-propyn-1-ol (propargyl alcohol)
2-Propyn-1-ol
1-Hydroxy-2-propyne
1-Propyn-3-ol
1-Propyn-3-yl alcohol
2-Propynol
2-Propynyl alcohol
3-Hydroxy-1-propyne
3-Hydroxypropyne
3-Propynol
Ethynylcarbinol
Hydroxymethylacetylene
NSC 8804
Propynyl alcohol
1-Hydroxy-2-propyne
1-Propyn-3-ol
1-Propyn-3-yl alcohol
1-hydroxy-2-propyne
1-propyn-3-ol
2-Propyn-1-ol (8CI, 9CI)
2-Propynol
2-Propynyl alcohol
2-propynol
2-propynyl alcohol
3-Hydroxy-1-propyne
3-Propynol
3-hydroxy-1-propyne
3-propynol
Ethynylcarbinol
Propargyl alcohol
Propynyl alcohol
acetylene carbinol
ethynylcarbinol
methanol, ethynyl-
propargyl alcohol
propiolic alcohol
propynyl alcohol
2-Propyn-1-ol
1-Hydroxy-2-propyne
1-Propyn-3-ol
1-Propyn-3-yl alcohol
2-Propynol
2-Propynyl alcohol
3-Hydroxy-1-propyne
3-Hydroxypropyne
3-Propynol
Ethynylcarbinol
Hydroxymethylacetylene
NSC 8804
Propynyl alcohol
Propargyl alcohol
2-propyn-1-ol
prop-2-yn-1-ol
2-PROPYN-1-OL
PROPYNOL
PROPINOL
2-Propynol
1-Propyn-3-ol
PROPYNYL ALCOHOL
1-Propyn-3-yl alcohol
NA 1986
3-Propynol
1-Hydroxy-2-propyne
1-Propyn-3-ol
1-Propyn-3-yl alcohol
1-Propyne-3-ol
2-Propyn-1-ol
2-Propynol
2-Propynyl alcohol
2-propyn-1-ol (propargyl alcohol)
3-Hydroxy-1-propyne
3-Propynol
Ethynyl carbinol
HC«equiv»CCH2OH
HC«equiv»CCH2OH
Methanol, ethynyl-
NSC 8804
Propynyl alcohol
Rcra waste number P102
prop-2-yn-1-ol
2-Propyn-1-ol
Prop-2-yn-1-ol
Prop-2-yne-1-ol
Prop-2-in-1-ol
1-Hydroxy-2-propyne
1-Propyn-3-ol
1-Propyn-3-yl alcohol
2-Propynol
2-Propynyl alcohol
3-Hydroxy-1-propyne
3-Propynol
Ethynylcarbinol
NA 1986
Propargyl alcohol
Propynyl alcohol
PA
PROPYNOL
PROPINOL
2-Propynol
3-PROPYNOL
1-Propyn-3-ol
2-PROPYN-1-OL
prop-2-yn-1-ol
prop-1-yn-1-ol
2-Propyny-1-0l
PROPYNYL ALCOHOL
Propargyl alcohol
PROPARGYL ALCOHOL
2-Propynyl alcohol
2-propynyl alcohol
3-Hydroxy-1-propyne
1-Propyn-3-yl alcohol
LABOTEST-BB LT01409238
2-propyn-1-ol (propargyl alcohol)
Propynyl alcohol
1-Hydroxy-2-propyne
1-Propyn-3-ol
Ethynyl carbinol
1-Propyne-3-ol
3-Hydroxy-1-propyne
Propyn-1-ol
1-Propyn-3-yl alcohol
prop-2-yn-1-ol
Acetylene carbinol
Ethynyl methanol
Methanol, ethynyl-
2-Propynol 2-Propyn-1-ol
Propargyl alcohol
HC=CCH2OH
3-Propynol
2-Propynyl alcohol
Rcra waste number P102
2-Propynol
NSC 8804
3-Hydroxy-1-propyne Propiolic alcohol
2-Propynyl alcohol
3-Hydroxy-1-propyne
Hydroxymethylacetylene
3-Hydroxypropyne
1-Propyn-3-ol
Ethynylcarbinol
1-Hydroxy-2-propyne, 3-Propynol
NSC 8804
Propynyl alcohol
1-Propyn-3-yl alcohol
2-Propynol
Propargyl alcohol



PROPILEN GLIKOL BUTIL ETER (PNB)
METHYL DIISOPROPYL PROPIONAMIDE. N° CAS : 51115-67-4. Nom INCI : METHYL DIISOPROPYL PROPIONAMIDE. Nom chimique : Butanamide, N,2,3-trimethyl-2-(1-methylethyl)-. N° EINECS/ELINCS : 256-974-4. Ses fonctions (INCI). Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit
PROPIONALDEHYDE
Propionaldehyde is a colorless, flammable liquid with a slightly fruity odor and is produced on a large scale industrially.
Propionaldehyde is predominantly used as a precursor to trimethylolethane (CH3C(CH2OH)3) through a condensation reaction with formaldehyde, an important intermediate in the production of alkyd resins.
Propionaldehyde has been isolated from various plant sources, such as hops, banana, sweet or sour cherry, blackcurrants, melon, pineapple, bread, cheeses, coffee, cooked rice, and strawberry or apple aroma.

CAS Number: 123-38-6
EC Number: 204-623-0
Molecular Formula: C3H6O
Molecular Weight (g/mol): 58.08

Synonyms: Propionaldehyde, propanal, 123-38-6, Methylacetaldehyde, Propaldehyde, Propanaldehyde, n-Propanal, Propylaldehyde, Propional, Propionic aldehyde, Propylic aldehyde, 1-Propanal, Propyl aldehyde, Aldehyde propionique, n-Propionaldehyde, Propanalaldehyde, Proprionaldehyde, 1-Propanone, FEMA No. 2923, NCI-C61029, NSC 6493, C2H5CHO, AMJ2B4M67V, DTXSID2021658, CHEBI:17153, NSC-6493, UN 1275, 25722-18-3, Propionaldehyd, FEMA Number 2923, Propionaldehyde (natural), Aldehyde propionique [French], CCRIS 2917, HSDB 1193, EINECS 204-623-0, MFCD00007020, UN1275, UNII-AMJ2B4M67V, proprionaldhyde, propion aldehyde, AI3-16114, methyl acetaldehyde, Propionaldehyde, 97%, ETHYLCARBOXALDEHYDE, EC 204-623-0, WLN: VH2, PROPIONALDEHYDE [MI], PROPIONALDEHYDE [FCC], PROPIONALDEHYDE [FHFI], PROPIONALDEHYDE [HSDB], CHEMBL275626, DTXCID001658, Propionaldehyde, >=97%, FG, BDBM60952, NSC6493, ZINC895256, Propionaldehyde, analytical standard, STR01357, Tox21_201071, Propionaldehyde, reagent grade, 97%, STL264226, AKOS000119167, Propionaldehyde, natural, >=98%, FG, NCGC00091772-01, NCGC00091772-02, NCGC00258624-01, CAS-123-38-6, FT-0655858, P0498, EN300-19153, C00479, Propionaldehyde [UN1275] [Flammable liquid], A805061, Q422909, J-004931, J-524059, F2190-0621, 2,5-Dioxo-1-[[1-oxo-6-[[1-oxo-3-(2-pyridinyldithio)propyl]amino]hexyl]oxy]-3-pyrrolidinesulfonic Acid Monosodium Salt;, 123-38-6 [RN], 1-Propanal, 1-Propanone, 204-623-0 [EINECS], Aldehyde propionique, n-Propanal, n-Propionaldehyde, Propanal [ACD/Index Name] [ACD/IUPAC Name], Propanalaldehyde, Propanaldehyde, Propionaldehyd [German], Propionaldehyde [Wiki], Propionaldéhyde [French], PROPIONIC ALDEHYDE, Proprionaldehyde, 15843-24-0 [RN], 198710-93-9 [RN], 39493-21-5 [RN], methyl acetaldehyde, Methylacetaldehyde, n-Propylal, Propaldehyde, Propanal;Propionaldehyde, Propanal-2,2,3,3,3-d5(9CI), PROPANAL-2,2-D2, Propanal204-623-0MFCD00007020, Propional, Propionaldehyde|Propanal, Propionaldehyde-2,2,3,3,3-d5, Propionaldehyde-2,2-d2, Propyl aldehyde, Propylaldehyde, Propylic aldehyde, STR01357, WLN: VH2

Propionaldehyde or propanal is the organic compound with the formula CH3CH2CHO.
Propionaldehyde is the 3-carbon aldehyde.

Propionaldehyde is a colourless, flammable liquid with a slightly fruity odour.
Propionaldehyde is produced on a large scale industrially.

Propionaldehyde is the chemical intermediate in the production of propionic acid.
Propionaldehyde is also used for the production of Perstorp’s Bis-MPA.
Propionaldehyde could also be used to produce various chemical compounds used in pharmaceutical applications, plastics, plasticizers, lacquers, flavourings, cellulose and rubber chemicals.

Propionaldehyde, belongs to the class of organic compounds known as aldehydes.
These are aldehydes with the general formula HC(H)(R)C(=O)H, where R is an organic group.

In organic chemistry, propanal or propionaldehyde is the aldehyde of the 3-carbon propyl group.
Propionaldehyde has a chemical formula of CH3CH2CHO and is a structural isomer of propanone.

Propionaldehyde is a colourless liquid with a slightly irritating, fruity odour, at room temperature.
Researchers have recently discovered two new interstellar molecules one of which is Propionaldehyde.

Propionaldehyde was located within the Milky Way Galaxy inside an interstellar cloud known as Sagittarius B2.
Propionaldehyde is used as a flavouring agent.
Propionaldehyde has been isolated from various plant sources, such as hops, banana, sweet or sour cherry, blackcurrants, melon, pineapple, bread, chesses, coffee, cooked rice and strawberry or apple aroma.

Propionaldehyde, belongs to the class of organic compounds known as alpha-hydrogen aldehydes.
These are aldehydes with the general formula HC(H)(R)C(=O)H, where R is an organyl group.

Propionaldehyde exists in all living species, ranging from bacteria to humans.
Propionaldehyde is an alcohol, cocoa, and earthy tasting compound.

Outside of the human body, Propionaldehyde is found, on average, in the highest concentration within wild celeries and carrots.
Propionaldehyde has also been detected, but not quantified in several different foods, such as purple lavers, black salsifies, strawberry guava, grapefruit/pummelo hybrids, and alaska wild rhubarbs.
Propionaldehyde is an aldehyde that consists of ethane bearing a formyl substituent.

Propanal or propionaldehyde is the aldehyde of the 3 carbon propyl group.
Propionaldehyde has a chemical formula of CH3CH2CHO, and is a structural isomer of propanone.
At room temperature, Propionaldehyde is a colourless liquid with a slightly irritating, fruity odour.

Propionaldehyde is principally used as a precursor to trimethylolethane (CH3C(CH2OH)3) through a condensation reaction with formaldehyde; this triol is an important intermediate in the production of alkyd resins.
Other applications include reduction to propanol and oxidation to propionic acid.

Propionaldehyde is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.
Propionaldehyde is used by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Propionaldehyde appears as a clear colorless liquid with an overpowering fruity-like odor.
Propionaldehyde is flash point 15 °F.

Propionaldehyde is used in the manufacture of plastics, in the synthesis of rubber chemicals, and as a disinfectant and preservative.
Limited information is available on the health effects of propionaldehyde.
No information is available on the acute (short-term), chronic (long-term), reproductive, developmental or carcinogenic effects of propionaldehyde in humans.

Animal studies have reported that exposure to high levels of propionaldehyde, via inhalation, results in anesthesia and liver damage, and intraperitoneal exposure results in increased blood pressure.
EPA has not classified propionaldehyde for carcinogenicity.

Propanal, also known as N-propionaldehyde or C2H5CHO, belongs to the class of organic compounds known as alpha-hydrogen aldehydes.
These are aldehydes with the general formula HC(H)(R)C(=O)H, where R is an organyl group.

Propionaldehyde is an extremely weak basic (essentially neutral) compound (based on Propionaldehyde pKa).
Propionaldehyde exists in all living species, ranging from bacteria to humans.

Propionaldehyde is a flammable, colorless liquid with an unpleasant, suffocating, fruity odor similar to acetaldehyde.
Propionaldehyde is miscible with alcohol, ether, chloroform, and water.
Propionaldehyde reacts vigorously with oxidizers and polymerizes with addition of methyl methacrylate.

Propionaldehyde applications include as an intermediate, in pharmaceuticals, perfumes, plastics and polyols or polyhydric alcohols.
Propionaldehyde is also used as a precursor to trimethylolethane (CH3C(CH2OH)3) through a condensation reaction with formaldehyde, this triol is an important intermediate in the production of alkyd resins.

Other applications include reduction to propanol and oxidation to propionic acid.
Propionaldehyde is also used in PEGylated protein purification.

Propionaldehyde is a volatile organic compound, which belongs to the class of flavor & fragrance standards for use in the food, beverage and cosmetic industry.
These standards are widely used to add taste and/or smell to products without aroma, to mask unpleasant odors and to maintain stability of original flavor.
Propionaldehyde is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food.

Applications of Propionaldehyde:
Propionaldehyde applications include as an intermediate, in pharmaceuticals, perfumes, plastics and polyols or polyhydric alcohols.
Propionaldehyde is also used as a precursor to trimethylolethane (CH3C(CH2OH)3) through a condensation reaction with formaldehyde, this triol is an important intermediate in the production of alkyd resins.

Other applications include reduction to propanol and oxidation to propionic acid.
Propionaldehyde is also used in PEGylated protein purification.

Propionaldehyde may be used as an analytical reference standard for the quantification of the analyte in:
Food products and cosmetics using gas-chromatography with photo ionization detection (GC-PID).
Infant formulas using gas chromatography with flame ionization detection (GC-FID).
Household products using gas chromatography coupled to mass spectrometry (GC-MS).

Other Applications:
Food flavors & food fragrances
Fragrance
Herbicides - intermediate for other
Polymer modification
Process solvents

Uses of Propionaldehyde:
Propionaldehyde is predominantly used as a precursor to trimethylolethane (CH3C(CH2OH)3) through a condensation reaction with formaldehyde.
This triol is an important intermediate in the production of alkyd resins.

Propionaldehyde is used in the synthesis of several common aroma compounds (cyclamen aldehyde, helional, lilial).
Other applications include reduction to propanol and oxidation to propionic acid.

Propionaldehyde is used to make propionic acid, trimethylolethane, polyvinyl and other plastics, and rubber, medicinal, and agricultural chemicals.
Propionaldehyde is also used as a disinfectant, preservative, and flavoring agent.

Propionaldehyde is used as a chemical intermediate in closed systems and not contained in consumer products.
Propionaldehyde is used almost exclusively (thought to be >99%) as a closed system intermediate and transported by bulk carrier.

Laboratory Uses:
Propionaldehyde is a common reagent, being a building block to many compounds.
Many of these uses exploit Propionaldehyde participation in condensation reactions.
With tert-butylamine Propionaldehyde gives CH3CH2CH=N-t-Bu, a three-carbon building block used in organic synthesis.

Widespread uses by professional workers:
Propionaldehyde is used in the following products: laboratory chemicals and pH regulators and water treatment products.
Propionaldehyde is used in the following areas: health services and scientific research and development.
Other release to the environment of Propionaldehyde is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

Uses at industrial sites:
Propionaldehyde is used in the following products: pH regulators and water treatment products and laboratory chemicals.
Propionaldehyde has an industrial use resulting in manufacture of another substance (use of intermediates).

Propionaldehyde is used in the following areas: health services and scientific research and development.
Propionaldehyde is used for the manufacture of: chemicals.
Release to the environment of Propionaldehyde can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), in processing aids at industrial sites and as processing aid.

Industry Uses:
Intermediate
Intermediates
Monomers

Consumer Uses:
Fragrance

Industrial Processes with risk of exposure:
Using Disinfectants or Biocides

Properties of Propionaldehyde:
Propionaldehyde is a colorless, flammable liquid, having a suffocating odor.
Propionaldehyde should be used as a chemical intermediate only.

Propionaldehyde undergoes reactions typical for the low molecular weight aldehydes, which, because of the terminal carbonyl group, are very reactive.
Contamination or the exposure to elevated temperatures may induce a hazardous polymerization.
Propionaldehyde is readily oxidized if in contact to oxygen and should therefore be stored under inert gases.

Physical Properties:
Propionaldehyde is a colorless, flammable liquid with a suffocating fruity odor.
The odor threshold for propionaldehyde is 1 part per million (ppm).

The chemical formula for propionaldehyde is C3H6O, and the molecular weight is 58.08 g/mol.
The vapor pressure for propionaldehyde is 317 mm Hg at 25 °C.

Production of Propionaldehyde:
Propionaldehyde is mainly produced industrially by hydroformylation of ethylene:
CO + H2 + C2H4 → CH3CH2CHO

In this way, several hundred thousand tons are produced annually.

Laboratory preparation of Propionaldehyde:
Propionaldehyde may also be prepared by oxidizing 1-propanol with a mixture of sulfuric acid and potassium dichromate.
The reflux condenser contains water heated at 60 °C, which condenses unreacted propanol, but allows propionaldehyde to pass.

The propionaldehyde vapor is immediately condensed into a suitable receiver.
In this arrangement, any propionaldehyde formed is immediately removed from the reactor, thus Propionaldehyde does not get over-oxidized to propionic acid.

General Manufacturing Information of Propionaldehyde:

Industry Processing Sectors:
All Other Basic Organic Chemical Manufacturing
Paint and Coating Manufacturing
Petrochemical Manufacturing

Reactions of Propionaldehyde:
Propionaldehyde exhibits the reactions characteristic of alkyl aldehydes, e.g. hydrogenation, aldol condensations, oxidations, etc.
Propionaldehyde is the simplest aldehyde with a prochiral methylene such that α-functionalized derivatives (CH3CH(X)CHO) are chiral.

Extraterrestrial Occurrence of Propionaldehyde:
Propionaldehyde along with acrolein has been detected in the molecular cloud Sagittarius B2 near the center of the Milky Way Galaxy, about 26,000 light years from Earth.
Measurements by the COSAC and Ptolemy instruments on comet 67/P's surface, revealed sixteen organic compounds, four of which were seen for the first time on a comet, including acetamide, acetone, methyl isocyanate and propionaldehyde.

Action Mechanism of Propionaldehyde:
Inhibition of intercellular communication is an important feature in the tumor promotion phase of a multistage carcinogenesis model.
In atherosclerosis inhibition of cell-cell communication by atherogenic compounds, e.g., low density lipoproteins (LDL), also seems to be important.

For testing atherogenic compounds we used an atherosclerosis relevant cell type, namely human smooth muscle cells. In order to investigate which part of the LDL particle would be involved in inhibition of metabolic co-operation between human smooth muscle cells in culture several fatty acids and their breakdown products were tested, namely aldehydes.
Unsaturated C-18 fatty acids markedly influenced gap-junctional intercellular communication (GJIC), whereas saturated (C18:0, C16:0) and unsaturated fatty acids with > 20 carbon atoms did not inhibit GJIC.

In the case of oleic and elaidic acid, orientation seemed important; however, after exposure to palmitoleic and palmitelaidic acid no differences were found.
The most potent inhibitor of GJIC was linoleic acid, which inhibited GJIC by 75%.

No correlation was found between degrees of unsaturation and ability to inhibit GJIC.
Of the tested aldehydes, hexanal, Propionaldehyde, butanal and 4-hydroxynonenal did significantly inhibit GJIC, while pentanal had no effect.
Since modification of LDL was shown to be important in order for LDL to inhibit GJIC, these results show that fatty acids and their oxidative breakdown products may be of importance for the inhibition of GJIC by LDL.

Reactivity Profile of Propionaldehyde:
Propionaldehyde may form explosive peroxides.
Reacts vigorously with oxidizing agents.

Explosive in the form of vapor when exposed to heat or flame.
Incompatible with strong bases and strong reducing agents.

Vigorous polymerization reaction with methyl methacrylate.
Polymerization may also occur in the presence of acids or caustics.

Handling and Storage of Propionaldehyde:

Nonfire Spill Response:
ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.
All equipment used when handling Propionaldehyde must be grounded.

Do not touch or walk through spilled material.
Stop leak if you can do it without risk.

Prevent entry into waterways, sewers, basements or confined areas.
A vapor-suppressing foam may be used to reduce vapors.

Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers.
Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL:
Dike far ahead of liquid spill for later disposal.
Water spray may reduce vapor, but may not prevent ignition in closed spaces.

Safe Storage of Propionaldehyde:
Separated from acids, bases and oxidants.
Keep in the dark.
Store only if stabilized.

Storage Conditions:
Store in cool, dry, well-ventilated location.
Store away from heat and oxidizers.

Outside or detached storage is preferred.
Inside storage should be in a standard flammable liquids storage warehouse, room, or cabinet.

Separate from oxidizing materials and other reactive hazards.
Store in cool, well ventilated area away from oxidizers.

Where possible, automatically pump liquid from drums or other storage containers to process containers.
Metals containers involving the transfer of 5 gallons or more of this chemical should be grounded or bonded.

Drums must be equipped with self-closing valves, pressure vacuum bungs, and flame arresters.
Use only non-sparking tools and equipment, especially when opening and closing containers of this chemical.

First Aid Measures of Propionaldehyde:

EYES:
First check the victim for contact lenses and remove if present.
Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center.

Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN:
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing.
Gently wash all affected skin areas thoroughly with soap and water.

IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop.
IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.

INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital.

Provide proper respiratory protection to rescuers entering an unknown atmosphere.
Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION:
DO NOT INDUCE VOMITING.
Corrosive chemicals will destroy the membranes of the mouth, throat, and esophagus and volatile chemicals have a high risk of being aspirated into the victim's lungs during vomiting.

Thus, the risk of increasing the medical problems by inducing vomiting of a volatile corrosive chemical is very high.
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center.

IMMEDIATELY transport the victim to a hospital.
If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body.

DO NOT INDUCE VOMITING.
IMMEDIATELY transport the victim to a hospital.

Fire Fighting of Propionaldehyde:
The majority of these products have a very low flash point.
Use of water spray when fighting fire may be inefficient.

SMALL FIRE:
Dry chemical, CO2, water spray or alcohol-resistant foam.
Do not use dry chemical extinguishers to control fires involving nitromethane (UN1261) or nitroethane (UN2842).

LARGE FIRE:
Water spray, fog or alcohol-resistant foam.
Avoid aiming straight or solid streams directly onto the product.
If Propionaldehyde can be done safely, move undamaged containers away from the area around the fire.

FIRE INVOLVING TANKS OR CAR/TRAILER LOADS:
Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.
Cool containers with flooding quantities of water until well after fire is out.

Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
ALWAYS stay away from tanks engulfed in fire.

For massive fire, use unmanned master stream devices or monitor nozzles.
If this is impossible, withdraw from area and let fire burn.

Identifiers of Propionaldehyde:
CAS Number: 123-38-6
3DMet: B01258
ChEBI: CHEBI:17153
ChEMBL: ChEMBL275626
ChemSpider: 512
ECHA InfoCard: 100.004.204
EC Number: 204-623-0
KEGG: C00479
PubChem CID: 527
RTECS number: UE0350000
UNII: AMJ2B4M67V
UN number: 1275
CompTox Dashboard (EPA): DTXSID2021658
InChI: InChI=1S/C3H6O/c1-2-3-4/h3H,2H2,1H3
Key: NBBJYMSMWIIQGU-UHFFFAOYSA-N
SMILES: CCC=O

CAS number: 123-38-6
EC index number: 605-018-00-8
EC number: 204-623-0
Hill Formula: C₃H₆O
Chemical formula: CH₃CH₂CHO
Molar Mass: 58.08 g/mol
HS Code: 2912 19 00

EC / List no.: 204-623-0
CAS no.: 123-38-6
Mol. formula: C3H6O

Synonym(s): Propanal
Linear Formula: CH3CH2CHO
CAS Number: 123-38-6
Molecular Weight: 58.08
Beilstein: 506010
EC Number: 204-623-0
MDL number: MFCD00007020
PubChem Substance ID: 329820216

CAS: 123-38-6
Molecular Formula: C3H6O
Molecular Weight (g/mol): 58.08
MDL Number: MFCD00007020
InChI Key: NBBJYMSMWIIQGU-UHFFFAOYSA-N
PubChem CID: 527
ChEBI: CHEBI:17153
IUPAC Name: propanal
SMILES: CCC=O

Typical Properties of Propionaldehyde:
Chemical formula: C3H6O
Molar mass: 58.080 g·mol−1
Appearance: Colourless liquid
Odor: Pungent, fruity
Density: 0.81 g cm−3
Melting point: −81 °C (−114 °F; 192 K)
Boiling point: 46 to 50 °C (115 to 122 °F; 319 to 323 K)
Solubility in water: 20 g/100 mL
Magnetic susceptibility (χ): -34.32·10−6 cm3/mol
Viscosity: 0.6 cP at 20 °C
Structure
Molecular shape: C1, O: sp2 C2, C3: sp3
Dipole moment: 2.52 D

Boiling point: 47 - 48 °C (1013 hPa)
Density: 0.80 g/cm3 (20 °C)
Explosion limit: 2.3 - 21 %(V)
Flash point: -30 °C
Ignition temperature: 175 °C
Melting Point: -81 °C
Vapor pressure: 400.46 hPa (23.61 °C)
Solubility: 200 g/l

Vapor density: 2 (vs air)

Vapor pressure
18.77 psi ( 55 °C)
4.89 psi ( 20 °C)

Assay: 97%
Autoignition temp.: 404 °F

Expl. lim.
17 %, 26 °F
2.6 %, 31 °F

Refractive index: n20/D 1.362 (lit.)
bp: 46-50 °C (lit.)
mp: −81 °C (lit.)
Density: 0.805 g/mL at 25 °C (lit.)
Storage temp.: 2-8°C
SMILES string: [H]C(=O)CC
InChI: 1S/C3H6O/c1-2-3-4/h3H,2H2,1H3
InChI key: NBBJYMSMWIIQGU-UHFFFAOYSA-N

Boiling Point/Range: 46-50 °C (1.013 hPa)
Color: Colorless
Density: 0.81 g/cm3 (20 °C)
Flashpoint: -40 °C
Form: Liquid
Grade: Reagent Grade
Incompatible Materials: Strong oxidizing agents, Alkalis
Lower Explosion Limit: 2.3 %(V)
Melting Point/Range: -81 °C
Partition Coefficient: 0.59 (25 °C)
Purity Percentage: 97.00
Purity Details: 97.00%
Solubility in Water: 306 g/l (25 °C)
Upper Explosion Limit: 21 %(V)
Vapor Density: 2.01
Vapor Pressure: 341 hPa (20 °C)
Viscosity: 0.317 mPa.s (26.7 °C)
Storage Temperature: Ambient

Molecular Weight: 58.08
XLogP3: 0.6
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 1
Exact Mass: 58.041864811
Monoisotopic Mass: 58.041864811
Topological Polar Surface Area: 17.1 Ų
Heavy Atom Count: 4
Complexity: 17.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Propionaldehyde:
Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.797 - 0.802
Water (GC): ≤ 2.0 % (a/a)
Identity (IR): passes test

Melting Point: -81°C
Density: 0.81
Boiling Point: 47°C to 49°C
Flash Point: −40°C (−40°F)
Odor: Pungent
Refractive Index: 1.362
Quantity: 500 mL
UN Number: UN1275
Beilstein: 506010
Sensitivity: Air sensitive
Merck Index: 14,7823
Solubility Information: Fully miscible in water.
Formula Weight: 58.08
Percent Purity: 97%
Chemical Name or Material: Propionaldehyde

Identity (IR): complying
Assay (GC): Min. 97.0 %
Water (Karl Fischer): Max. 2.5 %
APHA: Max. 10
Autoignition Temperature: 404 °F
Explosion Limit: 2.6 %, 31 °F
Vapor Pressure: 18.77 psi ( 55 °C)
Refractive Index: n20/D 1.362(lit.)
Vapor Density: 2 (vs air)
Explosion Limit: 17 %, 26 °F

Related Products of Propionaldehyde:
Nivalenol
(R)-Ochratoxin α
Di-N-heptytin Dichloride-D30
Ergosinine
3-Ethyl-2-methylpentane

Related compounds of Propionaldehyde:

Related aldehydes:
Acetaldehyde
Butyraldehyde

Names of Propionaldehyde:

IUPAC name:
Propionaldehyde

Preferred IUPAC name:
Propanal

Other names:
Methylacetaldehyde
Propionic aldehyde
Propaldehyde
Propan-1-one
PROPIONIC ACID
cas no 105-37-3 Propionic acid, Ethyl ester; Ethyl n-propionate; Propionic ether, Propionic ester; Propionate d'ethyle; Ethylester kyseliny propionove; Ethyl ester of propanoic acid; ETHYL PROPIONATE;
Propoxylated 1,6-Hexanediol Diacrylate
1-Acetoxy-2-butoxyethane; Ethanol, 2-butoxy-, acetate; Butylcellosolve acetate; Ethylene glycol mono-n-butyl ether acetate; Butylglycol acetate; Acetic acid, 2-butoxyethyl ester; 2-Butoxyethanol acetate; 2-Butoxyethylester kyseliny octove; Butylcelosolvacetat; Ektasolve eb acetate; Glycol monobutyl ether acetate; Butoxyethyl acetate; Ethylene glycol butyl ether acetate; Butoxyethanol acetate; n-Butyl cellosolve acetate; 2-Butoxyethyl acetate; cas no: 112-07-2
Propoxylated Glycerol Triacrylate
SYNONYMS Hydroacrylic acid; Carboxyethane; Methylacetic acid; C-3 Acid; Metacetonic acid; Pseudoacetic acid; Ethylformic Acid; Ethanecarboxylic Acid; Acide Propionique; Kyselina Propionova; Propanyl acid; CAS NO. 79-09-4, 784139-72-6
Propoxylated Neopentyl Glycol Diacrylate
cas no 105-37-3 Propionic acid, Ethyl ester; Ethyl n-propionate; Propionic ether, Propionic ester; Propionate d'ethyle; Ethylester kyseliny propionove; Ethyl ester of propanoic acid; ETHYL PROPIONATE;
PROPYL ALCOHOL
PROPYL ALCOHOL, N° CAS : 71-23-8, Nom INCI : PROPYL ALCOHOL. Nom chimique : Propan-1-ol. N° EINECS/ELINCS : 200-746-9. Classification : Alcool. Ses fonctions (INCI)Anti-moussant : Supprime la mousse lors de la fabrication / réduit la formation de mousse dans des produits finis liquides. Solvant : Dissout d'autres substances. Noms français : 1-HYDROXYPROPANE ; 1-PROPANOL; 1-PROPYL ALCOHOL; Alcool propylique; Alcool propylique normal; N-PROPANOL; PROPANOL; PROPANOL-1; PROPYL ALCOHOL (NORMAL-). Noms anglais : ETHYL CARBINOL; n-Propanol (n-Propyl alcohol); n-Propyl alcohol; NORMAL PROPYL ALCOHOL; Propyl alcohol, PROPYLIC ALCOHOL. Utilisation : L'alcool propylique normal est utilisé dans une grande gamme d'applications industrielles, notamment: comme solvant pour les résines, les cires et les huiles végétales dans certains cosmétiques, lotions dentaires et produits pharmaceutiques; comme antiseptique; dans la synthèse organique; 1-Propanol; n-PROPANOL (PROPYL ALCOHOL, NORMAL); propan-1-ol; n-propanol. : 1-propanolo; 2propan-1-ol; N-propyl alcohol; n-Propyl alcohol, 1-Propanol; propan- 1-olo; Propan-1-ol (n-Propanol); propan-1-oln-propanol; PROPYL ALCOHOL; Tyzor NPZ. Translated names: 1-пропанол (bg); alkohol propylowy (pl) ; n-propanol (cs); n-propanoli (fi); n-propanolis (lt); n-propanolo (it); n-propanols (lv); n-propanool (et); n-προπανόλη (el); n-пропанол (bg); Propaan-1-ol (nl); Propaan-1-ool (et); propan-1-ol (cs); Propan-1-oli (fi); Propan-1-olis (lt); Propan-1-olo (it); Propane-1-ol (fr);propanol (sk); Propán-1-ol (hu); Propān-1-ols (lv); Προπαν-1-όλη (el); Пропан-1-ол (bg). : 1-propanolo; 2propan-1-ol; N-propyl alcohol; n-Propyl alcohol, 1-Propanol; propan- 1-olo; Propan-1-ol (n-Propanol); propan-1-oln-propanol; PROPYL ALCOHOL; Tyzor NPZ. Trade names: 1-Hydroxypropan; 1-Hydroxypropane; 1-Propanol (9CI); Ethylcarbinol; Propanol-1; Propyl alcohol (8CI); Propylalkohol; Propylol; 109-78-4 [RN] ; 1-HYDROXYPROPANE; 1-Propanol [ACD/Index Name] ; 1-Propanol [German] ; 1-Propanol [French] ; 1-Propyl alcohol; 1-プロパノール [Japanese]; 1-丙醇 [Chinese]; Alcohol, propyl; Alcool propilico; Alcool propilico [Italian]; Alcool propylique ; Alcool propylique [French]; Hydroxypropane; n-propan-1-ol; n-propanol; n-Propyl alcohol; n-Propyl alkohol [German]; n-Propylalkohol; Propan-1-ol ; Propane-1-ol; propanol [German]; Propanol, 1-; propanol-1; propyl alcohol; Propylowy alkohol [Polish]; γ-Propanol; Propanolen; 1-Propanol, 99%; 1-Propanol, anhydrous; 200-661-7 [EINECS]; 2-Propen-1-ol ; Albacol; ethyl carbinol; Ethylcarbinol ; n-C3H7OH; N-Propanol ACS grade; Optal; Osmosol extra; oxabutane; POL; Policosanol; Propan-1-ol, GlenDry, anhydrous; Propan-1-ol, GlenPure; propanol; Propanole; Propyl alcohol200-746-; 9MFCD00002941; propylalcohol; Propylic alcohol; WLN: Q3; 正丙醇 [Chinese]
PROPYL ALCOHOL
CAS: 71-23-8
European Community (EC) Number: 200-746-9
Molecular Formula: C3H8O
Molecular Weight: 60.10 g/mol
IUPAC Name: propan-1-ol



DESCRIPTION:
Propan-1-ol (also propanol, n-propyl alcohol) is a primary alcohol with the formula CH3CH2CH2OH and sometimes represented as PrOH or n-PrOH.
Propyl alcohol is a colorless liquid and an isomer of 2-propanol.
Propyl alcohol is formed naturally in small amounts during many fermentation processes and used as a solvent in the pharmaceutical industry, mainly for resins and cellulose esters, and, sometimes, as a disinfecting agent.
Propyl alcohol is a metabolite found in or produced by Saccharomyces cerevisiae.

Propyl alcohol appears as a clear colorless liquid with a sharp musty odor like rubbing alcohol.
Flash point of Propyl alcohol is 53-77 °F.
Propyl alcohol Autoignites at 700 °F.
Vapors of Propyl alcohol are heavier than air and mildly irritate the eyes, nose, and throat.
Density of Propyl alcohol is approximately 6.5 lb / gal.
Propyl alcohol is Used in making cosmetics, skin and hair preparations, pharmaceuticals, perfumes, lacquer formulations, dye solutions, antifreezes, rubbing alcohols, soaps, window cleaners, acetone and other chemicals and products.

Propyl alcohol is the parent member of the class of Propyl alcohol that is propane in which a hydrogen of one of the methyl groups is replaced by a hydroxy group.
Propyl alcohol has a role as a protic solvent and a metabolite.
Propyl alcohol is a short-chain primary fatty alcohol and a member of propan-1-ols.
Propyl alcohol is a clear liquid commonly used as a germ killer (antiseptic).
Propyl alcohol is the second most commonly ingested alcohol after ethanol (drinking alcohol).

CHEMICAL PROPERTIES OF PROPYL ALCOHOL:
Chemical formula: C3H8O
Molar mass: 60.096 g•mol−1
Appearance: Colorless liquid
Odor: mild, alcohol-like[2]
Density: 0.803 g/mL
Melting point: −126 °C; −195 °F; 147 K
Boiling point: 97 to 98 °C; 206 to 208 °F; 370 to 371 K
Solubility in water: miscible
log P: 0.329
Vapor pressure: 1.99 kPa (at 20 °C)
Acidity (pKa): 16
Basicity (pKb): −2
Magnetic susceptibility (χ): −45.176•10−6 cm3/mol
Refractive index (nD): 1.387
Viscosity: 1.959 mPa•s (at 25 °C) [3]
Dipole moment: 1.68 D
Thermochemistry:
Heat capacity (C): 143.96 J/(K•mol)
Std molar entropy (S⦵298): 192.8 J/(K•mol)
Std enthalpy of formation (ΔfH⦵298): −302.79…−302.29 kJ/mol
Std enthalpy of combustion (ΔcH⦵298): −2.02156…−2.02106 MJ/mol

Molecular Weight: 60.10
XLogP3: 0.3
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 1
Exact Mass: 60.057514874
Monoisotopic Mass: 60.057514874
Topological Polar Surface Area: 20.2 Ų
Heavy Atom Count: 4
Formal Charge: 0
Complexity: 7.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
vapor pressure: 19 hPa ( 20 °C)
Quality Level: 200
Assay:≥98% (GC)
Form: liquid
evapn. Residue: ≤0.01%
Color: APHA: ≤10
pH: 7 (20 °C, 200 g/L in H2O)
Bp: 96.5-98 °C/1013 hPa
Mp: -127 °C
Transition temp: flash point 15 °C

Specifications:
Assay (by GC) Min 99.5 %
Calcium (Ca) Max 0.00002 %
Colour APHA Max 10
Copper (Cu) Max 0.000002 %
Ethanol Max 0.01 %
Iron (Fe) Max 0.00001 %
Lead (Pb) Max 0.000002 %
Magnesium (Mg) Max 0.00001 %
Methanol Max 0.005 %
Potassium (K) Max 0.00002 %
Propan-2-ol Max 0.005 %
Residue after evaporation (ppm) Max 10
Sodium (Na) Max 0.0001 %
Substances darkened by H2SO4
(APHA) Max 10



Propyl alcohol shows the normal reactions of a primary alcohol.
Thus propyl alcohol can be converted to alkyl halides; for example red phosphorus and iodine produce n-propyl iodide in 80% yield, while PCl3 with catalytic ZnCl2 gives n-propyl chloride.
Reaction with acetic acid in the presence of an H2SO4 catalyst under Fischer esterification conditions gives propyl acetate, while refluxing propanol overnight with formic acid alone can produce propyl formate in 65% yield.

Oxidation of propyl alcohol with Na2Cr2O7 and H2SO4 gives a 36% yield of propionaldehyde, and therefore for this type of reaction higher yielding methods using PCC or the Swern oxidation are recommended.
Oxidation with chromic acid yields propionic acid.

PREPARATION PROPERTIES OF PROPYL ALCOHOL:
Propyl alcohol is manufactured by catalytic hydrogenation of propionaldehyde.
Propionaldehyde is produced via the oxo process by hydroformylation of ethylene using carbon monoxide and hydrogen in the presence of a catalyst such as cobalt octacarbonyl or a rhodium complex.
H2C=CH2 + CO + H2 → CH3CH2CH=O
CH3CH2CH=O + H2 → CH3CH2CH2OH
A traditional laboratory preparation of propyl alcohol involves treating n-propyl iodide with moist Ag2O.

PROPYL ALCOHOL AS FUEL:
Propyl alcohol has high octane number and is suitable for engine fuel usage.
However, Propyl alcohol is too expensive to use as a motor fuel.
The research octane number (RON) of Propyl alcohol is 118, and anti-knock index (AKI) is 108



SAFETY INFORMATION ABOUT PROPYL ALCOHOL:
Propyl alcohol is thought to be similar to ethanol in its effects on the human body, but 2–4 times more potent.
Oral LD50 in rats is 1870 mg/kg (compared to 7060 mg/kg for ethanol).
Propyl alcohol is metabolized into propionic acid.
Effects include alcoholic intoxication and high anion gap metabolic acidosis.
As of 2011, one case of lethal propyl alcohol poisoning was reported
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.



SYNONYMS OF PROPYL ALCOHOL:
MeSH Entry Terms:
1-Propanol
Alcohol, Propyl
n-Propanol
Propanol
Propyl Alcohol

Depositor-Supplied Synonyms:
1-propanol
propanol
Propan-1-ol
Propyl alcohol
n-propanol
71-23-8
n-Propyl alcohol
ethylcarbinol
1-hydroxypropane
optal
Policosanol
osmosol extra
Propylic alcohol
Propanol-1
1-Propyl alcohol
n-Propan-1-ol
Propanolen
Propanole
Alcohol, propyl
Propanoli
Ethyl carbinol
Alcool propilico
Alcool propylique
n-Propyl alkohol
Propylowy alkohol
1-PROPONOL
propane-1-ol
142583-61-7
propylalcohol
FEMA No. 2928
NSC 30300
n-PrOH
Propylan-propyl alcohol
MFCD00002941
CHEBI:28831
96F264O9SV
NSC-30300
UN 1274
1-Propanol, anhydrous
Albacol
POL
Propanole [German]
Propanolen [Dutch]
Propanol, 1-
Propanoli [Italian]
Propyl alcohol, normal
Caswell No. 709A
FEMA Number 2928
Propyl alcohol (natural)
1 Propanol
Alcool propilico [Italian]
Alcool propylique [French]
n-Propyl alkohol [German]
Propylowy alkohol [Polish]
Propyl alcohol, n-
CCRIS 3202
HSDB 115
EINECS 200-746-9
UN1274
EPA Pesticide Chemical Code 047502
BRN 1098242
Hydroxypropane
ethyl methanol
n-propylalcohol
normal propanol
n-Propylalkohol
UNII-96F264O9SV
AI3-16115
62309-51-7
3-propanol
nPrOH
HOPr
PrOH
normal propyl alcohol
N-Propanol ACS grade
n-C3H7OH
1-Propanol, HPLC Grade
DSSTox_CID_1739
bmse000446
N-PROPANOL [HSDB]
PROPANOL [WHO-DD]
1-Propanol, >=99%
EC 200-746-9
DSSTox_RID_76299
PROPYL ALCOHOL [MI]
DSSTox_GSID_21739
PROPYL ALCOHOL [FCC]
WLN: Q3
4-01-00-01413 (Beilstein Handbook Reference)
CHEMBL14687
PROPYL ALCOHOL [FHFI]
PROPYL ALCOHOL [INCI]
1-PROPANOL [USP-RS]
1-Propanol, analytical standard
1-Propanol, JIS special grade
PROPANOL [EP MONOGRAPH]
PROPYL ALCOHOL [MART.]
1-Propanol, >=99%, FG
1-Propanol, LR, >=99%
DTXSID2021739
1-Propanol, >=99.80%
BDBM36153
Propyl Alcohol (Fragrance Grade)
PROPYL ALCOHOL (PROPANOL)
1-Propanol, anhydrous, 99.7%
1-Propanol, p.a., 99.5%
ZINC895969
1-Propanol, AR, >=99.5%
AMY11110
NSC30300
Tox21_302440
1-Propanol, Spectrophotometric Grade
LMFA05000101
n-Propanol or propyl alcohol, normal
STL264225
1-Propanol, natural, >=98%, FG
Hydroxypropyl cellulose-SL (HPC-SL)
1-Propanol, >=99% (GC), purum
AKOS000249219
1-Propanol, for HPLC, >=99.5%
1-Propanol, for HPLC, >=99.9%
DB03175
1-Propanol, ACS reagent, >=99.5%
1-Propanol, HPLC grade, >=99.5%
CAS-71-23-8
1-Propanol, purum, >=99.0% (GC)
NCGC00255163-01
1-Propanol 100 microg/mL in Acetonitrile
1-Propanol, SAJ first grade, >=99.0%
Propyl Alcohol (Normal) Reagent Grade ACS
FT-0608280
FT-0608281
FT-0627482
P0491
1-Propanol, UV HPLC spectroscopic, 99.0%
C05979
Q14985
A837125
J-505102
1-Propanol, for inorganic trace analysis, >=99.8%
1-Propanol, B&J Brand (product of Burdick & Jackson)
F0001-1829
Z955123580
1-Propanol, puriss. p.a., Reag. Ph. Eur., >=99.5% (GC)
1-Propanol, United States Pharmacopeia (USP) Reference Standard
n-Propanol or propyl alcohol, normal [UN1274] [Flammable liquid]
1-Propanol, Pharmaceutical Secondary Standard; Certified Reference Material
5VQ
71-31-8






PROPYL ETHANOATE
Propyl ethanoate (also known as 1-propyl acetate, propyl acetate, 1-acetoxypropane, acetic acid) is an organic compound with a molecular formula of C5H10O2 / CH3COOCH2CH2CH3.
Propyl ethanoate is commonly used as a solvent in coatings and printing inks.
Propyl ethanoate is highly flammable and Propyl ethanoate is abundantly miscible with all common organic solvents (alcohols, ketones, glycols, esters) but has only slight miscibility in water.

CAS Number: 109-60-4
EC Number: 203-686-1
Chemical Formula: CH3COOCH2CH2CH3
Molecular Weight: 102.13

Propyl ethanoate, also known as N-propyl acetate, is an organic compound.
Nearly 20,000 tons are produced annually for use as a solvent.

Propyl ethanoate is known by its characteristic odor of pears.
Due to this fact, Propyl ethanoate is commonly used in fragrances and as a flavor additive.
Propyl ethanoate is formed by the esterification of acetic acid and propan-1-ol, often via Fischer–Speier esterification, with sulfuric acid as a catalyst and water produced as a byproduct.

Propyl ethanoate (also known as 1-propyl acetate, propyl acetate, 1-acetoxypropane, acetic acid) is an organic compound with a molecular formula of C5H10O2 / CH3COOCH2CH2CH3.
Propyl ethanoate is a clear, colourless ester that has a distinguishable acetate odour, is highly flammable, highly miscible with all common organic solvents (alcohols, ketones, glycols, esters) but only slightly miscible in water.

Propyl ethanoate appears as a clear colorless liquid with a pleasant odor.
Propyl ethanoate is flash point 58 °F.
Propyl ethanoate is less dense than water, Vapors are heavier than air.

Propyl ethanoate is an acetate ester obtained by the formal condensation of acetic acid with propanol.
Propyl ethanoate has a role as a fragrance and a plant metabolite.
Propyl ethanoate is functionally related to a propan-1-ol.

Propyl ethanoate is a clear, colourless liquid with a distinctive, pleasant fruity odour.
Propyl ethanoate is readily miscible with most organic solvents such as alcohol, ketones, glycols and esters, but Propyl ethanoate has only limited miscibility with water.

Propyl ethanoate is an organic compound with a molecular formula of C5H10O2.
Propyl ethanoate is a clear, colourless liquid that has a distinguishable acetate odor.

Propyl ethanoate is highly flammable and Propyl ethanoate is abundantly miscible with all common organic solvents (alcohols, ketones, glycols, esters) but has only slight miscibility in water.
Propyl ethanoate is commonly used as a solvent in coatings and printing inks.

Propyl ethanoate is an organic chemical compound, more specifically, an ester of acetic acid and propanol.
Propyl ethanoate is obtained by esterification of propanol with acetic acid in the presence of a catalyst.

Propyl ethanoate is also known as N-propyl acetate and is widely used as a solvent, but its characteristic odor makes Propyl ethanoate a fragrance as well.

Propyl ethanoate, also known as “propyl acetate” or “Acetic acid propyl ester”, naturally exists in strawberries, bananas and tomatoes.
Propyl ethanoate is synthetically produced by having acetic acid and 1-propanol undergoing esterification reaction.

Propyl ethanoate is a colorless transparent liquid at room temperature with typical ester properties.
Propyl ethanoate has a special fruity odor and can be dissolved in both ethanol and ethyl ether.

Propyl ethanoate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Propyl ethanoate is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Propyl ethanoate (also known as 1-propyl acetate) is an organic compound with a molecular formula of C5H10O2.
Propyl ethanoate is commonly used as a solvent in coatings and printing inks.

Propyl ethanoate is a clear, colourless liquid that has a distinguishable acetate odour.
Propyl ethanoate is highly flammable with a flash point of 14° C and a flammability rating of 3.
Propyl ethanoate is highly miscible with all common organic solvents (alcohols, ketones, glycols, esters) but has only slight miscibility in water.

Propyl ethanoate is a colorless, volatile solvent with an odor similar to acetone.
Propyl ethanoate has good solvency power for many natural and synthetic resins.
Propyl ethanoate is miscible with many organic solvents.

Propyl ethanoate is an ester with an average evaporation rate and high degree of solubility in the major resins on the market, such as nitrocellulose, and synthetic and natural resins.
Propyl ethanoate is used in formulations for paints and thinners for different applications, including printing inks (rotogravure and flexography), industrial coatings, original automotive paints and car refinishing.
In printing inks, Propyl ethanoate also stands out for its low retention in flexible polyethylene and polypropylene films.

Propyl ethanoate is a colorless, volatile solvent with an odor similar to acetone.
Propyl ethanoate has good solvency power for many natural and synthetic resins.
Propyl ethanoate is miscible with many organic solvents.

Propyl ethanoate is the propyl ester of acetic acid.

Propyl ethanoate, also known as 1-acetoxypropane or N-propyl acetate, belongs to the class of organic compounds known as carboxylic acid esters.
These are carboxylic acid derivatives in which the carbon atom from the carbonyl group is attached to an alkyl or an aryl moiety through an oxygen atom (forming an ester group).

Propyl ethanoate exists as a clear, colourless liquid with fruity odor and has a bittersweet flavor reminiscent of pear on dilution.
Propyl ethanoate is commonly used in fragrances and as a flavor additive.
Its fruity aroma accounts for the aroma of passion fruit pulps (0.1% - 0.16% relative to total volatile compounds), melons, apples (4.57% - 9.89% relative to total aroma volatiles), and pears (1.31 mg/L in pear juice).

Propyl ethanoate is acts as a clear, colorless, volatile solvent for coatings, printing inks and chemical downstream industries.
Propyl ethanoate is possesses a characteristic odor reminiscent of acetone and a good solvent power for numerous natural and synthetic resins.

Propyl ethanoate is exhibits miscibility with many common solvents, e.g. alcohols, ketones, ethers, aldehydes, glycols and glycol ethers, but sparingly soluble in water.
Propyl ethanoate is used for coatings applications like wood lacquers and industrial finishes and for printing inks applications like flexographic and special screen inks.

Propyl ethanoate (nPAC) is an organic compound with the formula C5H10O2.
Propyl ethanoate is most used as solvent in lacquer, paint and chemistry industry.

Propyl ethanoate is a highly miscible organic solvent.
Propyl ethanoate is used in the production of fragrances and nail care products.

Propyl ethanoate is used as a solvent.
Propyl ethanoate plays an important role in the printing inks industry are flexographic and special screen printing inks.

Propyl ethanoate is widely used in fragrances and as a flavor additive due to its odor.
Propyl ethanoate acts as a good solvent for cellulose nitrate, acrylates, alkyd resins, rosin, plasticizers, waxes, oils and fats.

Propyl ethanoate is a chemical compound used as a solvent and an example of an ester.
Propyl ethanoate is known by its characteristic odor of pears.

Due to this fact, Propyl ethanoate is commonly used in fragrances and as a flavor additive.
Propyl ethanoate is formed by the esterification of acetic acid and 1-propanol (known as a condensation reaction), often via Fischer–Speier esterification, with sulfuric acid as a catalyst and water produced as a byproduct.

Propyl ethanoate, also known as 1-acetoxypropane or N-propyl acetate, belongs to the class of organic compounds known as carboxylic acid esters.
These are carboxylic acid derivatives in which the carbon atom from the carbonyl group is attached to an alkyl or an aryl moiety through an oxygen atom (forming an ester group).
Based on a literature review very few articles have been published oPropyl ethanoate.

Propyl ethanoate, also known as N-propyl acetate, is an organic compound with a molecular formula of C5H10O2.
Propyl ethanoate is a clear and colourless liquid with with a mild fruity odor.

Propyl ethanoate is highly flammable with a flash point of 14°C and a flammability rating of 3.
Propyl ethanoate is highly miscible with all common organic solvents (alcohols, ketones, glycols, esters) but has only slight miscibility in water.

Propyl ethanoate is found in apple and formed by the esterification of acetic acid and 1-propanol (known as acondensation reaction), often via Fischer–Speier esterification, with sulfuric acid as a catalyst and water produced as a byproduct.
Propyl ethanoate is primarily intended as a solvent in the coatings and printing inks industries.

Propyl ethanoate is widely used in fragrances and as a flavor additive due to its odor.
Propyl ethanoate also acts as a good solvent for cellulose nitrate, acrylates, alkyd resins, rosin, plasticizers, waxes, oils and fats.

Propyl ethanoate Market Outlook-2022-2032:
The global Propyl ethanoate market size is expected to reach a valuation of US$ 418.6 Mn by the end of 2022.
Sales of Propyl ethanoate are likely to expand at a CAGR of 5.4% from 2022 to 2032.

The global market is projected to top a valuation of US$ 706.3 Mn by the end of 2032.
Growing demand for Propyl ethanoate from the printing ink industry as a slow evaporation solvent is anticipated to drive the market during the projected period.

Propyl ethanoate, which is also known as N-propyl acetate, is an ester of acetic acid and n-propanol.
Propyl ethanoate is a clear, colorless liquid with a characteristic odor of peers and raspberry.

Propyl ethanoate is miscible with a wide variety of typical solvents, including alcohols, ketones, aldehydes, and glycol ethers, although in water Propyl ethanoate is only sparingly soluble.
Additionally, due to the presence of higher alkanes, Propyl ethanoate offers a slow rate of evaporation when used as an industrial solvent.

Owing to these characteristics, Propyl ethanoate is primarily implemented as a solvent for liquid, flexographic, and rotogravure printing inks.
In the cosmetics industry, Propyl ethanoate is used to make aerosol sprays, nail care products, cosmetics, and fragrances.

The growth of the Propyl ethanoate market is primarily driven by the printing ink industries.
Globally, these industries consume up to a one-third portion of the Propyl ethanoate and are expected to soar the demand in the forecast period.

The market for Propyl ethanoate is directly impacted by expansion in the printing ink sector.
The printing industry uses Propyl ethanoate extensively as a solvent, mostly for flexographic and screen printing inks.

Propyl ethanoate can thin a variety of different organic compounds, making Propyl ethanoate a useful solvent for this sector of the economy.
Particularly in emerging economies such as China and India, need for inks for paper media and packaging is surging.

The conventional ethyl acetate solvent in flexographic printing consumes more solvent, more ink, and requires flame retardants which hikes the printing costs.
However, with the use of Propyl ethanoate, high-quality flexography printings can be achieved with the consumption of 33% lesser solvent and 25% lesser ink which subsequently turns down the printing cost.
Thus, due to these improved benefits over ethyl acetate, Propyl ethanoate is quickly replacing Propyl ethanoate in the printing ink sector and will continue its growth in the forecast period.

Uses of Propyl ethanoate:
The major use of Propyl ethanoate is as a solvent in the coatings and printing industries.
Propyl ethanoate is a good solvent for these industries because Propyl ethanoate has the ability to thin many other organic compounds.

Propyl ethanoate dissolves a host of resins which make Propyl ethanoate a suitable solvent for wood lacquers and industrial finishes.
Within the printing industry Propyl ethanoate is mainly used in flexographic and special screening prints.

Propyl ethanoate is also used in aerosol sprays, nail care and as a fragrance solvent.
Propyl ethanoate can also be used as a flavouring additive due to its odour similar to pears.
The main user end markets are the printing, coatings, lacquers, cosmetic and flavouring industries.

Propyl ethanoate is used as a solvent, flavoring agent, and chemical intermediate.

Propyl ethanoate is flavoring agents, perfumery, solvent for nitrocellulose and other cellulose derivatives, natural and synthetic resins, lacquers, plastics, organic synthesis, lab reagent
Propyl ethanoate is a powerful solvent and is used in waxes, and insecticide formulations.

Propyl ethanoate is used in alcohol-dilutable inks containing nitrocellulose as a main constituent, polyamide inks, acrylic inks.

Widespread uses by professional workers:
Propyl ethanoate is used in the following products: coating products, laboratory chemicals, lubricants and greases, washing & cleaning products, inks and toners and metal working fluids.
Propyl ethanoate is used in the following areas: building & construction work and scientific research and development.

Propyl ethanoate is used for the manufacture of: , fabricated metal products, electrical, electronic and optical equipment and machinery and vehicles.
Other release to the environment of Propyl ethanoate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids) and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).

Uses at industrial sites:
Propyl ethanoate is used in the following products: coating products, washing & cleaning products, inks and toners, lubricants and greases and metal working fluids.
Propyl ethanoate has an industrial use resulting in manufacture of another substance (use of intermediates).

Propyl ethanoate is used for the manufacture of: chemicals.
Release to the environment of Propyl ethanoate can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and of substances in closed systems with minimal release.

Industry Uses:
Intermediate
Not Known or Reasonably Ascertainable
Other
Other (specify)
Paint additives and coating additives not described by other categories
Pigments
Solvent

Consumer Uses:
Propyl ethanoate is used in the following products: lubricants and greases, coating products, anti-freeze products, perfumes and fragrances, adhesives and sealants, washing & cleaning products, leather treatment products, cosmetics and personal care products and polishes and waxes.
Other release to the environment of Propyl ethanoate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids) and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).

Other Consumer Uses:
Not Known or Reasonably Ascertainable
Paint additives and coating additives not described by other categories
Pigments
Solvent

Industrial Processes with risk of exposure:
Painting (Solvents)
Plastic Composites Manufacturing

Applications of Propyl ethanoate:
Propyl ethanoate is mainly used as a solvent in the industrial production of coatings and printing inks (owing to its suitability to thin down many other organic compounds).
Propyl ethanoate is also an excellent solvent for many natural and synthetic resins (such as cellulose nitrate, acrylates, colophony, plastifiers, wax, oils and fats), varnishes for wood, natural and synthetic dyes and plastics.
Propyl ethanoate is also used to produce insecticides and in the perfume, printing and food industry (as a flavor additive for food lending Propyl ethanoate the taste and flavor of a pear).

Propyl ethanoate mainly used as solvent in printing inks, especially in flexographic and special screen printing inks, also used as a safe and pro-environment solvent for food package printing ink industry and used in PTA(purified tereph-thalic acid) industry.
With strong ability to dissolve many natural and synthetic resins (e.g. cellulose nitrate, acrylates, alkyd resin) Coatings for automotive and plastic Solvents for cosmetics and personal care, for fragrances.

Propyl ethanoate is used as an active solvent in many ink and coating applications.
For cosmetics and personal care, Propyl ethanoate can be used in nail care or as a flavoring agent.
In addition, Propyl ethanoate has been listed as Inert Ingredients Permitted for Use in Nonfood Use Pesticide Products under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA).

Propyl ethanoate is used as a solvent.
Propyl ethanoate plays an important role in the printing inks industry are flexographic and special screen printing inks.

Propyl ethanoate is widely used in fragrances and as a flavor additive due to its odor.
Propyl ethanoate acts as a good solvent for cellulose nitrate, acrylates, alkyd resins, rosin, plasticizers, waxes, oils and fats.

Propyl ethanoate is primarily used as a solvent in the manufacture of paints and coatings because of its ability to thin many other organic compounds.
Propyl ethanoate has the power to dissolve a wide range of resins, which also makes Propyl ethanoate highly suitable as a solvent for wood lacquers and industrial finishes.

Propyl ethanoate is widely used in the printing industry, mainly for flexographic and screen printing inks.
Propyl ethanoate is also used as a solvent in perfumes and is found as an ingredient in aerosol sprays, nail care products and cosmetics.

Propyl ethanoate is used as an intermediate in organic chemistry of pharmaceutical compounds.
Propyl ethanoate is also used as a flavouring additive on account of its fruity odour, which is similar to pears.

Other Applications:
Coatings
Wood lacquers
Aerosol sprays
Nail care
Cosmetic / personal care solvent
Fragrance solvent
Process solvent
Printing inks (especially flexographic and special screen)

Features of Propyl ethanoate:
Propyl ethanoate’s main application is in the printing inks industry for flexographic and special screen printing inks.
Propyl ethanoate is slightly soluble in water but is miscible with alcohols, ketones, esters and hydrocarbons.
Propyl ethanoate is a suitable fluid for blended products requiring variation in end-use performance.

Other Features:
Clear, highly volatile liquid
Mild odor
Sparingly soluble in water
Good resin solvent
Slow RER
Promotes flow and leveling
Non-HAP (Hazardous Air Pollutant) Solvent
Solvency power similar to ethyl acetate
Miscible with many organic solvents (alcohols, ketones, aldehydes, glycols and glycol ethers)

Manufacturing Methods of Propyl ethanoate:
Propyl ethanoate is produced by direct esterification of the corresponding alcohol with acetic acid in the presence of sulfuric acid, ptoluenesulfonic acid, methanesulfonic acid, or a strong cationic resin as catalyst.
1-Propanol can also undergo ester interchange with methyl or ethyl acetate in the presence of a strong cationic exchange resin to give Propyl ethanoate.

Propyl ethanoate is manufacture from acetic acid and mixture of propene and propane in the presence of zinc chloride catalyst.
Propyl ethanoate is manufacture from interaction of acetic acid and n-propyl alcohol in the presence of sulfuric acid.

Typical Properties of Propyl ethanoate:

Chemical Properties:
Propyl ethanoate has a fruity (pear–raspberry) odor with a pleasant, bittersweet flavor reminiscent of pear on dilution.
The Odor Threshold is 70 milligram per cubic meter and 2.8 milligram per cubic meter (New Jersey Fact Sheet).

Physical properties:
Clear, colorless, flammable liquid with a pleasant, pear-like odor.
Experimentally determined detection and recognition odor threshold concentrations were 200 μg/m3 (48 ppbv) and 600 μg/m3 (140 ppbv), respectively.

An odor threshold concentration of 240 ppbv was determined by a triangular odor bag method.
Cometto-Mu?iz and Cain (1991) reported an average nasal pungency threshold concentration of 17,575 ppmv.

General Manufacturing Information of Propyl ethanoate:

Industry Processing Sectors:
All Other Basic Organic Chemical Manufacturing
Miscellaneous Manufacturing
Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing)
Not Known or Reasonably Ascertainable
Oil and Gas Drilling, Extraction, and Support activities
Paint and Coating Manufacturing
Pharmaceutical and Medicine Manufacturing
Plastics Material and Resin Manufacturing
Printing Ink Manufacturing
Printing and Related Support Activities
Synthetic Dye and Pigment Manufacturing

Human Metabolite Information of Propyl ethanoate:

Cellular Locations:
Cytoplasm
Extracellular

Handling and Storage of Propyl ethanoate:

Nonfire Spill Response:
ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.
All equipment used when handling Propyl ethanoate must be grounded.

Do not touch or walk through spilled material.
Stop leak if you can do Propyl ethanoate without risk.

Prevent entry into waterways, sewers, basements or confined areas.
A vapor-suppressing foam may be used to reduce vapors.

Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers.
Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL:
Dike far ahead of liquid spill for later disposal.
Water spray may reduce vapor, but may not prevent ignition in closed spaces.

Storage and Handling of Propyl ethanoate:
Propyl ethanoate should be stored in a tightly-closed containerin a cool, dry, well-ventilated place away from direct sunlight, heat, sources of ignition and incompatible materials such as strong oxidizers, acids and bases.
Containers which have been opened should be carefully resealed and stored in an upright position to avoid leakage.

Handle in accordance with good industry practices for safety and hygiene.
Personal protective equipment including eye goggles and impermeable gloves and clothing should be worn to avoid contact with skin and eyes.
Appropriate engineering controls including sufficient natural or exhaust ventilation must be implemented and respiratory protection should be worn to prevent exposure to vapours.

Reactivity Profile of Propyl ethanoate:
Propyl ethanoate is an ester.
Propyl ethanoate is colorless, highly flammable liquid, moderately toxic.

Dangerous fire hazard when exposed to heat, flame, sparks, or strong oxidizers.
When heated to decomposition Propyl ethanoate emits acrid smoke and irritating fumes.

First Aid Measures of Propyl ethanoate:

Eye:
IRRIGATE IMMEDIATELY - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids.
Get medical attention immediately.

Skin:
WATER FLUSH PROMPTLY - If this chemical contacts the skin, flush the contaminated skin with water promptly.
If this chemical penetrates the clothing, immediately remove the clothing and flush the skin with water promptly.
If irritation persists after washing, get medical attention.

Breathing:
RESPIRATORY SUPPORT - If a person breathes large amounts of this chemical, move the exposed person to fresh air at once.
If breathing has stopped, perform artificial respiration.

Keep the affected person warm and at rest.
Get medical attention as soon as possible.

Swallow:
MEDICAL ATTENTION IMMEDIATELY - If this chemical has been swallowed, get medical attention immediately.

Fire Fighting of Propyl ethanoate:

CAUTION:
The majority of these products have a very low flash point.
Use of water spray when fighting fire may be inefficient.

SMALL FIRE:
Dry chemical, CO2, water spray or alcohol-resistant foam.
Do not use dry chemical extinguishers to control fires involving nitromethane (UN1261) or nitroethane (UN2842).

LARGE FIRE:
Water spray, fog or alcohol-resistant foam.
Avoid aiming straight or solid streams directly onto the product.
If Propyl ethanoate can be done safely, move undamaged containers away from the area around the fire.

FIRE INVOLVING TANKS OR CAR/TRAILER LOADS:
Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.
Cool containers with flooding quantities of water until well after fire is out.

Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
ALWAYS stay away from tanks engulfed in fire.

For massive fire, use unmanned master stream devices or monitor nozzles.
If this is impossible, withdraw from area and let fire burn.

Use alcohol-resistant foam, foam, powder, carbon dioxide, fine water spray.
In case of fire: keep drums, etc., cool by spraying with water.

Fire Fighting Procedures of Propyl ethanoate:

If material on fire or involved in fire:
Do not extinguish fire unless flow can be stopped or safely confined.
Use water in flooding quantities of fog.

Solid streams of water may be ineffective.
Cool all affected containers with flooding quantities of water.

Apply water from as far a distance as possible.
Use "alcohol foam, dry chemical or carbon dioxide.

Accidental Release Measures of Propyl ethanoate:

Isolation and Evacuation:

IMMEDIATE PRECAUTIONARY MEASURE:
Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

LARGE SPILL:
Consider initial downwind evacuation for at least 300 meters (1000 feet).

FIRE:
If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Spillage Disposal of Propyl ethanoate:
Remove all ignition sources.
Evacuate danger area!

Consult an expert! Personal protection:
Filter respirator for organic gases and vapours adapted to the airborne concentration of the substance.
Do NOT wash away into sewer.

Do NOT let this chemical enter the environment.
Collect leaking liquid in sealable containers.

Absorb remaining liquid in sand or inert absorbent.
Then store and dispose of according to local regulations.

Disposal Methods of Propyl ethanoate:
The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.
Recycle any unused portion of Propyl ethanoate for its approved use or return Propyl ethanoate to the manufacturer or supplier.

Ultimate disposal of the chemical must consider:
Propyl ethanoate's impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with environmental and public health regulations.

Preventive Measures of Propyl ethanoate:
The scientific literature for the use of contact lenses by industrial workers is inconsistent.
The benefits or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses.

However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye.
In those specific cases, contact lenses should not be worn.
In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Identifiers of Propyl ethanoate:
CAS Number: 109-60-4
ChEBI: CHEBI:40116
ChEMBL: ChEMBL44857
ChemSpider: 7706
DrugBank: DB01670
ECHA InfoCard: 100.003.352
EC Number: 203-686-1
PubChem CID: 7997
RTECS number: AJ3675000
UNII: 4AWM8C91G6
UN number: 1276
CompTox Dashboard (EPA): DTXSID6021901
InChI: InChI=1S/C5H10O2/c1-3-4-7-5(2)6/h3-4H2,1-2H3
Key: YKYONYBAUNKHLG-UHFFFAOYSA-N
InChI=1/C5H10O2/c1-3-4-7-5(2)6/h3-4H2,1-2H3
Key: YKYONYBAUNKHLG-UHFFFAOYAC
SMILES: O=C(OCCC)C

CAS number: 109-60-4
EC index number: 607-024-00-6
EC number: 203-686-1
Hill Formula: C₅H₁₀O₂
Chemical formula: CH₃COOCH₂CH₂CH₃
Molar Mass: 102.13 g/mol
HS Code: 2915 39 00

Synonyms: Propyl acetate
Linear Formula: CH3COOCH2CH2CH3
CAS Number: 109-60-4
Molecular Weight: 102.13

Molecular Weight:102.13200
Exact Mass:102.13
EC Number:203-686-1
UNII:4AWM8C91G6
ICSC Number:0940
NSC Number:72025
UN Number:1276
DSSTox ID:DTXSID6021901
Color/Form:Colorless liquid
HScode:2915390090

CAS: 109-60-4
Molecular Formula: C5H10O2
Molecular Weight (g/mol): 102.13
MDL Number: MFCD00009372
InChI Key: YKYONYBAUNKHLG-UHFFFAOYSA-N
PubChem CID: 7997
ChEBI: CHEBI:40116
IUPAC Name: propyl acetate
SMILES: CCCOC(C)=O

Linear Formula: CH3COOCH2CH2CH3
CAS Number: 109-60-4
Molecular Weight: 102.13
Beilstein: 1740764
EC Number: 203-686-1
MDL number: MFCD00009372
eCl@ss: 39022103
PubChem Substance ID: 329757979
NACRES: NA.21

Boiling point: 101.5 °C (1013 hPa)
Density: 0.89 g/cm3 (20 °C)
Explosion limit: 1.7 - 8 %(V)
Flash point: 11.8 °C
Ignition temperature: 430 °C
Melting Point: -95 °C
Vapor pressure: 33 hPa (20 °C)
Solubility: 21.2 g/l

Properties of Propyl ethanoate:
Chemical formula: C5H10O2
Molar mass: 102.133 g·mol−1
Appearance: Colorless liquid
Odor: Mild, fruity
Density: 0.89 g/cm3
Melting point: −95 °C (−139 °F; 178 K)
Boiling point: 102 °C (216 °F; 375 K)
Solubility in water: 18.9 g/L
Vapor pressure: 25 mmHg (20 °C)
Magnetic susceptibility (χ): −65.91·10−6 cm3/mol

PSA:26.30000
XLogP3:0.9595
Appearance:Colorless liquid with a strong odor
Density:0.836 g/cm3 @ Temp: 20 °C
Melting Point:-93 °C
Boiling Point:101.5 °C @ Press: 760 Torr
Flash Point:55 °F
Refractive Index:n20/D 1.384(lit.)
Water Solubility:H2O: 2g/100 mL (20 ºC)
Storage Conditions:Storage Room low temperature ventilation drying ,Separate storage with oxidizing agent
Vapor Pressure:35.2mmHg at 25°C
Vapor Density:3.5 (vs air)
Flammability characteristics:Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.
Explosive limit:vol% in air: 1.7.0
Odor:Pleasant odor
Taste:Pleasant, bittersweet flavor reminiscent of pear on dilution.
OH:3.40e-12 cm3/molecule*sec
Henrys Law Constant:2.18e-04 atm-m3/mole|Henry's Law constant = 2.18X10-4 atm-cu m/mol at 25 °C
Air and Water Reactions:Highly flammable. Slightly soluble in water.

Molecular Formula: C5H10O2 / CH3COOCH2CH2CH3
Cas Number: 109-60-4
Molecular Mass: 102.06808 g/mol
Flashpoint: 58 °F / 14.4 °C
Boiling Point: 214.9 ° F at 760 mm Hg
Melting Point: -139 °F / -95 °C
Vapour Pressure: 67.21 mm Hg
Water Solubility: g/100ml at 16 °C: 1.6
Density: 0.886 at 68 °F

vapor density: 3.5 (vs air)
Quality Level: 200
vapor pressure: 25 mmHg ( 20 °C)
Assay: ≥99.5%
form: liquid
autoignition temp.: 842 °F

expl. lim.:
1.7 %, 37 °F
8 %

impurities:
≤0.01% Acetic acid (free acid)
≤0.1% Water

evapn. residue: ≤0.01%
color: APHA: ≤15
refractive index: n20/D 1.384 (lit.)
bp: 102 °C (lit.)
mp: −95 °C (lit.)
density: 0.888 g/mL at 25 °C (lit.)
SMILES string: CCCOC(C)=O
InChI: 1S/C5H10O2/c1-3-4-7-5(2)6/h3-4H2,1-2H3
InChI key: YKYONYBAUNKHLG-UHFFFAOYSA-N

Molecular Weight: 102.13 g/mol
XLogP3: 1.2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 3
Exact Mass: 102.068079557 g/mol
Monoisotopic Mass: 102.068079557 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Count: 7
Complexity: 59.1
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Propyl ethanoate:
Melting Point: -92°C
Density: 0.887
Boiling Point: 99°C to 102°C
Flash Point: 14°C (57°F)
Odor: Fruit-like
Linear Formula: CH3CO2CH2CH2CH3
Refractive Index: 1.384
Quantity: 500 mL
UN Number: UN1276
Beilstein: 1740764
Merck Index: 14,7841
Solubility Information: Miscible with alcohols,ketones,aldehydes,ethers,glycols and glycol ethers. Slightly soluble in water.
Formula Weight: 102.13
Percent Purity: 99%
Chemical Name or Material: Propyl ethanoate

Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.886 - 0.888
Identity (IR): passes test

Related compounds ofPropyl ethanoate:
Propan-1-ol
Acetic acid

Related esters:
Ethyl acetate
Isopropyl acetate
n-butyl acetate
Isobutyl acetate

Names of Propyl ethanoate:

Regulatory process names:
1-Acetoxypropane
1-Propyl acetate
Acetate de propyle normal
Acetic acid n-propyl ester
Acetic acid, propyl ester
n-PROPYL ACETATE
n-Propyl acetate
n-Propyl acetate (natural)
n-Propyl ethanoate
Octan propylu
Propyl acetate
Propyl acetate
propyl acetate
Propyl ethanoate
Propylester kyseliny octove

Translated names:
acetat de propil (mt)
acetat de propil (ro)
acetato de propilo (es)
acetato de propilo (pt)
acetato di propile propilacetato (it)
acétate de propyle; (fr)
octan propylu (pl)
propil acetat (sl)
propil-acetát (hu)
propilacetatas (lt)
propilacetāts (lv)
propyl-acetát (cs)
propyl-acetát (sk)
propylacetaat (nl)
propylacetat (da)
Propylacetat (de)
propylacetat (no)
propylacetat (sv)
Propyyliasetaatti (fi)
propüülatsetaat (et)
οξικός προπυλεστέρας (el)
пропил ацетат (bg)

IUPAC names:
Acetic acid, propyl ester
Acetic acid, propylester
EC_203_686_1__propyl_acetate
n-propyl acetate
n-Propyl ethanoate
n-propyl ethanoate
NPAC
PROPYL ACETATE
Propyl Acetate
Propyl acetate
propyl acetate
Propyl Acetate
Propyl acetate
propyl acetate
PROPYL ACETATE, NORMAL
Propyl ethanoate
propyl ethanoate
propylacetate

Preferred IUPAC name:
Propyl acetate

Systematic IUPAC name:
Propyl ethanoate

Trade names:
1-Acetoxypropane
1-Propyl acetate
ACETATE, PROPYL
Acetic acid n-propyl ester
acetic acid propyl ester
Acetic acid, propyl ester
ESSIGSAEURE-PROPYLESTER
n-Propanol acetate
n-Propyl Acetate
n-Propyl acetate
n-propyl acetate
n-Propylacetat
NSC 72025
Pr acetate
propyl acetate
Propyl ethanoate
Propylacetat

Other names:
Acetic acid propyl ester
n-Propyl ethanoate
n-Propyl acetate
n-Propyl ester of acetic acid

Other identifiers:
109-60-4
607-024-00-6

Synonyms of Propyl ethanoate:
Propyl acetate
109-60-4
N-PROPYL ACETATE
Acetic acid, propyl ester
Propyl ethanoate
1-Acetoxypropane
1-Propyl acetate
n-Propyl ethanoate
Octan propylu
Acetic acid n-propyl ester
Propylacetate
Acetate de propyle normal
n-Propyl acetate (natural)
Acetic acid propyl ester
FEMA No. 2925
Propylester kyseliny octove
NSC 72025
HSDB 161
Octan propylu [Polish]
n-propanol acetate
EINECS 203-686-1
Acetic acid, n-propyl ester
UNII-4AWM8C91G6
BRN 1740764
4AWM8C91G6
DTXSID6021901
CHEBI:40116
AI3-24156
Acetate de propyle normal [French]
Propylester kyseliny octove [Czech]
NSC-72025
UN1276
DTXCID301901
ACETIC ACID,PROPYL ESTER
EC 203-686-1
4-02-00-00138 (Beilstein Handbook Reference)
PROPYL ACETATE (USP-RS)
PROPYL ACETATE [USP-RS]
n-propylacetat
n-Propyl ester of acetic acid
?Propyl acetate
acetic acid propyl
Propyl acetate, N-
ACETATE, PROPYL
Propyl acetate, 99%
PAT (CHRIS Code)
Actate de propyle normal
CH3COOCH2CH2CH3
Acetic acid-n-propyl ester
Propyl ester of acetic acid
PROPYL ACETATE [MI]
FEMA NUMBER 2935
SCHEMBL14991
PROPYL ACETATE [FCC]
WLN: 3OV1
CHEMBL44857
PROPYL ACETATE [FHFI]
PROPYL ACETATE [INCI]
Propyl acetate, >=99.5%
Propyl acetate, >=98%, FG
N-PROPYL ACETATE [HSDB]
N-Propyl acetate LBG-64752
Propyl acetate, analytical standard
ACETIC ACID, N-PROPYL ETHER
NSC72025
Tox21_202012
MFCD00009372
NA1276
STL280317
AKOS008949448
DB01670
LS-3066
UN 1276
NCGC00249148-01
NCGC00259561-01
CAS-109-60-4
A0044
FT-0621756
FT-0627474
Propyl acetate, natural, >=97%, FCC, FG
n-Propyl acetate [UN1276] [Flammable liquid]
n-Propyl acetate [UN1276] [Flammable liquid]
Q415750
J-002310
InChI=1/C5H10O2/c1-3-4-7-5(2)6/h3-4H2,1-2H
Propyl acetate, United States Pharmacopeia (USP) Reference Standard
Propyl Acetate, Pharmaceutical Secondary Standard; Certified Reference Material
109-60-4 [RN]
203-686-1 [EINECS]
Acétate de propyle [French] [ACD/IUPAC Name]
Acetic acid n-propyl ester
Acetic acid, n-propyl ester
Acetic acid, propyl ester [ACD/Index Name]
MFCD00009372 [MDL number]
n-propyl acetate
n-Propyl ethanoate
Propyl acetate [ACD/IUPAC Name]
Propyl ethanoate
Propyl-acetat [German] [ACD/IUPAC Name]
Propylester kyseliny octove [Czech]
1-Propyl acetate
3OV1 [WLN]
4-02-00-00138 (Beilstein Handbook Reference) [Beilstein]
4PA
ACETIC ACID PROPYL ESTER
Acetic acid-n-propyl ester
NORMAL PROPYL ACETATE
N-PROPANOL ACETATE
Octan propylu
Trimethylene acetate
WLN: 3OV1
PROPYL GALLATE
Propyl gallate is an antioxidant commonly used in foods, cosmetics, and pharmaceuticals to prevent the oxidation of fats and oils, thereby extending shelf life and maintaining product quality.
Propyl gallate is effective in protecting against oxidation by scavenging free radicals and is used in various applications including food preservation, anti-fade agents in microscopy, and stabilizers in pharmaceuticals.
Propyl gallate has been shown to possess antimicrobial and hepatoprotective properties, though its use should be monitored for potential allergic reactions and sensitivities.

CAS Number: 121-79-9
EC Number: 204-498-2
Molecular Formula: C10H12O5
Molecular Weight: 196.2 g/mol

Synonyms: Gallic acid propyl ester , PG, Propyl gallate, 98% 100GR, Propyl gallat, Propyl gallate,3,4,5-Trihydroxybenzoic acid propyl ester, Tenox PG, Propyl gallate 3g [121-79-9], Propyl gallate (200 mg)G2D2031.000mg/mg(dr), Propyl gallate (200 mg), Propyl gallate, USP, Propyl gallate SynonyMs: Propyl 3,4,5-trihydroxybenzoate, proply gallate, Propyl 3,4,5-trihydroxybenzoate 3,4,5-Trihydroxybenzoic acid propyl ester Tenox PG, Propyl 3,4,5-trihydroxybenzoate for synthesis, 3,4,5-TRIHYDROXYBENZENE-1-PROPYLCARBOXYLATE, 3,4,5-TRIHYDROXYBENZOIC ACID N-PROPYL ESTER, 3,4,5-TRIHYDROXYBENZOIC ACID PROPYL ESTER, n-propylesterof3,4,5-trihydroxybenzoicacid, Propyl galiate, propyl3,4,5-, Propylester kyseliny gallove, propylesterkyselinygallove, Sustane PG, Tenox PG, tenoxpg, GALLIC ACID N-PROPYL ESTER, GALLIC ACID PROPYL ESTER, FEMA 2947, FEMA 2974, n-Propyl gallate (Ph. Eur.) pure, pharma grade, Propyl gallate 121-79-9 Propyl 3,4,5-trihydroxybenzoate, Propyl 3,4,5-trihydroxybenzoate 121-79-9 Propyl gallate, PROGALLIN P, Propyl gallate, N-Propyl gallate, N-PROPYL 3,4,5-TRIHYDROXYBENZOATE, 3,4,5-trihydroxy-benzoicacipropylester, Benzoicacid,3,4,5-trihydroxy-,propylester, NCI-C50588, nci-c505888, Nipa 49, nipa49, Nipagallin P, nipagallinp, n-Propyl ester of 3,4,5-trihydroxybenzoic acid, L-A-PHOSPHATIDYLCHOLINE, B-OLEOYL,*GAMMA -MYRISTOYL, Propyl gallate, FOR MICROSCOPY, Propyl gallate 98+% FCC, PropylGallate(Antioxidant), PropylGallate-(N-Propyl-3,4,5-Trihydroxybezoate), Propyl gallate ,99%, Ethyl carbamate Solution, 1000ppm, Propyl gailate, Propyl gallate ,98%, Gallic acid propyl, Propyl 3,4,5-trihydroxybenzoate, 3,4,5-Trihydroxy-Benzoic, Propyl gallate USP/NF/FCC, PROPYLGALLATE,FCC, PROPYLGALLATE,NF

Propyl gallate is a chemical compound used primarily as an antioxidant.
Propyl gallate's primary function is to prevent the oxidation of fats and oils in food products, which helps to extend shelf life and maintain flavor and nutritional quality.
Propyl gallates often found in processed foods, cosmetics, and pharmaceuticals.

Propyl gallate, or propyl 3,4,5-trihydroxybenzoate is an ester formed by the condensation of gallic acid and propanol.
Since 1948, Propyl gallate has been added to foods containing oils and fats to prevent oxidation.
As a food additive, Propyl gallate is used under the E number E310.

Propyl gallate is an antioxidant.
Propyl gallate protects against oxidation by hydrogen peroxide and oxygen free radicals.

Propyl gallate (also known as propyl 3, 4, 5-trihydroxybenoate) is a kind of ester formed through the condensation of gallic acid and propanol.
Propyl gallate appears as a fine white to creamy-white crystalline powder.

Propyl gallate has long been used as a kind of antioxidants to be supplied to foods especially animal fats and vegetable oil, being especially effective with polyunsaturated fats.
Propyl gallate, as an anti-oxidant, can protect the food and oils from the attack of hydrogen peroxide and oxygen free radicals, having an effect similar to the superoxide dismutase.
Propyl gallate can also be applied to ethers, emulsion, waxes, and transformer oil as the antioxidants.

Propyl gallate caused contact dermatitis in a baker and in a female confectioner who fried doughnuts, primarily sensitized by her night cream; the margarine probably contained gallates.
Propyl gallate is an antioxidant with antimicrobial activity.

Propyl gallate is hepatoprotective in vitro and in vivo, preventing CCl4 induced lipoperoxidation and reduction in polysomes in rat liver.
Propyl gallate in combination with potassium sorbate is bactericidal and bacteriostatic against S. aureus strains known to produce enterotoxins in food. Propyl gallate is commonly added to foods to prevent autoxidation and microbial growth.

Propyl gallate appears as fine white to creamy-white crystalline powder.
Propyl gallate is odorless or with a faint odor.

Propyl gallate's melting point 150°C.
Propyl gallate is insoluble in water.
Propyl gallate is slightly bitter taste.

Propyl gallate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.
Propyl gallate is used by professional workers (widespread uses), in formulation or re-packing and at industrial sites.

Propyl gallate is the n-propyl ester of gallic acid (3,4,5-trihydroxybenzoic acid).
Propyl gallate is soluble in ethanol, ethyl ether, oil, lard, and aqueous solutions of polyethylene glycol (PEG) ethers of cetyl alcohol, but only slightly soluble in water.

Propyl gallate currently is used as an antioxidant in a reported 167 cosmetic products at maximum concentrations of 0.1%.
Propyl gallate is a generally recognized as safe (GRAS) antioxidant to protect fats, oils, and fat-containing food from rancidity that results from the formation of peroxides.

The biological activity of Propyl gallate is consistent with its free-radical scavenging ability, with effects that include antimicrobial activity, enzyme inhibition, inhibition of biosynthetic processes, inhibition of the formation of nitrosamines, anesthesia, inhibition of neuromuscular response to chemicals, ionizing/ultraviolet (UV) radiation protection, chemoprotection, antimutagenesis, anticarcinogenesis and antitumorigenesis, antiteratogenesis, and anticariogenesis.
Propyl gallate has being shown to be a hepatoprotector in vitro and in vivo.

Propyl gallate is an anti-fade reagent in fluorescence microscopy to reduce photobleaching of fluorescent probes such as rhodamine and fluorescein.
An antioxidant which exhibits antimicrobial activity.

Propyl gallate is an antioxidant with antimicrobial activity.
Propyl gallate is hepatoprotective in vitro and in vivo, preventing CCl4 induced lipoperoxidation and reduction in polysomes in rat liver.

1,2 Propyl gallate (100 mg/kg, i.p.) increases expression of HIF-1α, EPO, and VEGF mRNA levels and the number of normal neurons in rat brains after 8 minutes of forebrain ischemia.
Propyl gallate in combination with potassium sorbate is bactericidal and bacteriostatic against S. aureus strains known to produce enterotoxins in food.4 Propyl gallate is commonly added to foods to prevent autoxidation and microbial growth.

Propyl gallate, C10H12O5, is an ester formed from gallic acid and propanol.
Since 1948, this antioxidant has been added to foods containing oils and fats to prevent oxidation.

As a food additive, Propyl gallate is used under the E number E310.

Propyl gallate is an important antioxidant for the prevention of rancidity in edible oils and fats.
Gallic acid is 3,4,5-trihydroxybenzoic acid and has the formula (HO)3C6H2·CO2H.

Propyl gallate is found in foods, cosmetics, hair products, adhesives, and lubricants.
Propyl gallate is used to protect oils and fats from oxidation.

Uses of Propyl Gallate:
Propyl gallate is used to protect oils and fats in products from oxidation; Propyl gallate is used in foods, cosmetics, hair products, adhesives, and lubricants.
Propyl gallate is used as a triplet state quencher and an antioxidant in fluorescence microscopy.

Propyl gallate is used as an antioxidant for foods and cosmetics; especially fats, oils, emulsions, and waxes.
Propyl gallate is also used in transformer oils and as a stabilizer for synthetic vitamin A.

Reactive peroxides in povidone often lead to degradation of oxidation-labile drugs.
The antioxidants ascorbic acid, Propyl gallate, and sodium sulfite reduced the peroxide concentration in povidone.

Synthetic antioxidants commonly used in food include butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), Propyl gallate (PG), and tert-butylhydroquinone (TBHQ).

Industry Uses:
Oxidizing/reducing agents

Consumer Uses:
Cleaning and furnishing care products

Widespread uses by professional workers:
Propyl gallate is used in the following products: pH regulators and water treatment products and laboratory chemicals.
Propyl gallate is used in the following areas: health services and scientific research and development.
Other release to the environment of Propyl gallate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

Uses at industrial sites:
Propyl gallate is used in the following products: pH regulators and water treatment products and laboratory chemicals.
Propyl gallate is used in the following areas: health services and scientific research and development.

Propyl gallate is used for the manufacture of: chemicals and textile, leather or fur.
Release to the environment of Propyl gallate can occur from industrial use: as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates) and in processing aids at industrial sites.

Applications of Propyl Gallate:
Propyl gallate is used as an anti-fade reagent in fluorescence microscopy to reduce photobleaching of fluorescent probes such as rhodamine and fluorescein.

Pharmaceutical Applications:
Propyl gallate has become widely used as an antioxidant in cosmetics, perfumes, foods, and pharmaceuticals since its use in preventing autoxidation of oils was first described in 1943.
Propyl gallate is primarily used, in concentrations up to 0.1% w/v, to prevent the rancidity of oils and fats.
Propyl gallate may also be used at concentrations of 0.002% w/v to prevent peroxide formation in ether, and at 0.01% w/v to prevent the oxidation of paraldehyde.

Synergistic effects with other antioxidants such as butylated hydroxyanisole and butylated hydroxytoluene have been reported.
Propyl gallate is also said to possess some antimicrobial properties;

Studies have shown that, when added to powder blends containing ketorolac, Propyl gallate significantly increases the drug stability in the preparation.
Other alkyl gallates are also used as antioxidants and have approximately equivalent antioxidant properties when used in equimolar concentration, however, solubilities vary.

Biological effects of Propyl Gallate:
A 1993 study in fat rodents found little or no effect on carcinogenesis by Propyl gallate.
A 2009 study found that Propyl gallate acts as an estrogen antagonist.

Biochem/physiol Actions of Propyl Gallate:
An antioxidant that exhibits antimicrobial activity.
Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both in vitro and in vivo.

Propyl gallate has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis.
Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both in vitro and in vivo.

Propyl gallate has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis.
However, Propyl gallate induced single strand breaks in DNA at concentrations higher than 0.25 μM when Propyl gallate was combined with copper concentrations at 5 μM and above.

Propyl gallate (Gallic acid propyl esterZ, n-Propyl gallate) is an antioxidant used in foods especially animal fats and vegetable oils, also in a wide variety of cosmetics and beauty care products.
Propyl gallate (PG) could modulate heme oxygenase-1 (HO-1) activation and decrease lung cancer cell survival.

Propyl gallate also induces apoptosis in human leukemia cells and HeLa cells by increasing reactive oxygen species (ROS) levels and glutathione (GSH) depletion.
Propyl gallate inhibits the expression of MMP-2 and MMP-9 and exerts an antimigration effect on TMZ-treated U87MG cells.

Propyl gallate also possesses anti-inflammatory activity via downregulation of the NF-κB pathway.
Propyl gallate could reduce the proliferation and augment the chemosensitivity of a THP-1 leukemia cell line via extrinsic and intrinsic apoptotic pathways.

In brain ischemia, Propyl gallate inhibits the activity of NF-κB, reduces COX-2 and TNF-alpha G expression, and decreases ischemic-reperfusion injury.

Chemical Properties of Propyl Gallate:
Propyl gallate is an odorless powder having a slightly bitter taste.
Propyl gallate functions particularly well in stabilizing animal fats and vegetable oils.

With a melting point of 148°C, Propyl gallate loses its effectiveness during heat processing and is therefore not suitable in frying applications that involve temperatures exceeding 190°C.
Propyl gallate chelates iron ions and forms an unappealing, blue–black complex.

Hence, Propyl gallate is always used with chelators such as citric acid to eliminate the pro-oxidative iron and copper catalysts.
Good synergism is obtained with BHA and BHT; however, application with TBHQ is not permitted.
For additional details, refer to Burdock (1997).

Structure of Propyl Gallate:

Core Structure:
A benzene ring with three hydroxyl groups (-OH) attached at the 3, 4, and 5 positions.
This gives the ring Propyl gallate's characteristic "gallate" structure.

A propyl ester group attached to the benzene ring through a carboxyl group (-COO-).
The ester is formed by the esterification of the carboxyl group with propanol.

Detailed Structure:
The benzene ring is the central structure with hydroxyl groups at the 3, 4, and 5 positions, which are the ortho and para positions relative to each other.
The ester linkage connects the carboxyl group of the benzene ring to a propyl group (a three-carbon chain).

Handling and Storage of Propyl Gallate:

Handling:

Precautions:
Avoid inhalation, ingestion, and direct contact with skin and eyes.
Use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats.

Ventilation:
Work in a well-ventilated area or under a fume hood to avoid inhaling dust or vapors.

Hygiene:
Wash hands thoroughly after handling Propyl gallate.
Avoid eating, drinking, or smoking in areas where Propyl gallate is used.

Storage:
Propyl gallate is unstable at high temperatures and is rapidly destroyed in oils that are used for frying purposes.
The bulk material should be stored in a well-closed, nonmetallic container, protected from light, in a cool, dry place.

Conditions:
Store in a cool, dry place away from direct sunlight and sources of heat.
Keep containers tightly closed.

Container:
Use appropriate containers that are compatible with Propyl gallate.
Typically, Propyl gallate should be stored in airtight, moisture-proof containers.

Separation:
Keep away from strong acids, bases, and oxidizing agents to prevent potential reactions.

Reactivity and Stability of Propyl Gallate:

Reactivity:

Conditions to Avoid:
Avoid exposure to high temperatures, strong acids, bases, and oxidizing agents.
Propyl gallate can decompose under extreme conditions.

Hazardous Reactions:
May react with strong acids and bases, potentially leading to hazardous decomposition products.

Stability:

Stability:
Stable under normal conditions of use and storage.

Decomposition Products:
In case of decomposition, Propyl gallate may produce fumes or gases that could be harmful if inhaled.

Ventilation:

Requirement:
Ensure adequate ventilation in areas where Propyl gallate is used.
Use local exhaust ventilation or a fume hood if working with large quantities or in a confined space.

First Aid Measures of Propyl Gallate:

Inhalation:
Move the person to fresh air immediately.
If symptoms persist, seek medical attention.

Skin Contact:
Wash the affected area with plenty of water and soap.
Remove contaminated clothing.
Seek medical attention if irritation persists.

Eye Contact:
Rinse immediately with plenty of water for at least 15 minutes, holding the eyelids open.
Seek medical attention immediately.

Ingestion:
Rinse the mouth with water.
Do not induce vomiting unless directed by a medical professional.
Seek medical attention immediately.

Fire Fighting Measures of Propyl Gallate:

Suitable Extinguishers:
Use dry chemical powder, foam, or carbon dioxide (CO₂) extinguishers.

Unsuitable Extinguishers:
Avoid using water if Propyl gallate can spread the fire or cause hazardous reactions.

Fire Fighting Procedures:

Precautions:
Wear self-contained breathing apparatus and full protective gear.
Use water spray to cool containers exposed to fire and prevent the spread of fire.

Hazardous Combustion Products:

Possible Products:
Combustion may produce hazardous fumes or gases.
Be aware of potential exposure risks during a fire.

Accidental Release Measures of Propyl Gallate:

Personal Precautions:

Protective Equipment:
Wear appropriate PPE, including gloves, safety goggles, and masks.

Avoid Contact:
Avoid inhaling dust or vapors and prevent contact with skin and eyes.

Containment and Cleanup:

Containment:
Isolate the area and prevent the spread of the spill.
Use barriers or absorbents to contain the material.

Cleanup:
Collect the spilled material using suitable tools and dispose of Propyl gallate according to local regulations.
Clean the area thoroughly with an appropriate solvent or detergent.

Disposal:

Regulations:
Follow local regulations for the disposal of chemical waste.
Ensure that disposal methods do not harm the environment.

Exposure Controls/Personal Protective Equipment of Propyl Gallate:

Exposure Limits:

Standards:
Refer to occupational exposure limits established by regulatory agencies, though Propyl gallate typically does not have specific exposure limits.

PPE Recommendations:

Eye Protection:
Safety goggles or face shield.

Skin Protection:
Chemical-resistant gloves and lab coats.

Respiratory Protection:
Use an N95 respirator or higher if there is a risk of inhaling dust or vapors.

Ventilation:
Ensure adequate ventilation or use a fume hood when handling large quantities.

Identifiers of Propyl Gallate:
Chemical Name: Propyl gallate
IUPAC Name: Propyl 3,4,5-trihydroxybenzoate
CAS Number: 121-79-9
Molecular Formula: C10H12O5
Molecular Weight: 196.2 g/mol
SMILES: CCCC(=O)O[C@H]1Oc2c(C=CC)cc(c2O)O1
InChI: InChI=1S/C10H12O5/c1-2-3-4-13-10(12)8-5-6(11)7(9(8)14)15/h5-7,11-14H,2-4H2,1H3
InChIKey: XWDFUBTNVVIGKP-UHFFFAOYSA-N

EC / List no.: 204-498-2
CAS no.: 121-79-9
Mol. formula: C10H12O5

Properties of Propyl Gallate:
Physical State: Solid (typically a white to off-white powder)
Melting Point: Approximately 125–129°C (257–264°F)
Boiling Point: Not well-defined, as it decomposes before boiling

Solubility:
In Water: Very low solubility
In Organic Solvents: Soluble in ethanol, acetone, and other organic solvents

Density: Approximately 1.29 g/cm³
Odor: Generally odorless
pH: Neutral to slightly acidic in solution
Chemical Stability: Stable under normal conditions of use and storage. However, Propyl gallate can decompose under high temperatures or in the presence of strong acids or bases.
Reactivity: Propyl gallate is relatively stable but can undergo hydrolysis under acidic or basic conditions.
Appearance: White to off-white crystalline powder

Specifications of Propyl Gallate:

Purity:

Minimum Purity: Often required to be at least 98% or higher by weight.
Test Method: Typically determined by high-performance liquid chromatography (HPLC) or similar analytical techniques.

Appearance:
Color: White to off-white crystalline powder.
Odor: Odorless or with a faint characteristic odor.

Melting Point:
Range: Approximately 125–129°C (257–264°F).

Loss on Drying:
Maximum Limit:
Usually less than 1% to ensure that the substance is not excessively hygroscopic.

Heavy Metals:
Maximum Limit:
Typically less than 10 ppm (parts per million) or as specified by regulatory standards to ensure safety.

Arsenic:
Maximum Limit:
Usually less than 1 ppm.

Assay:
Minimum:
Should meet the assay requirements of 98% or higher as determined by specific analytical methods.

Residue on Ignition:
Maximum Limit:
Often less than 0.1% to ensure purity.

Acidity/Alkalinity:
Should be neutral or slightly acidic.

Names of Propyl Gallate:

IUPAC Names:
3,4,5-trihydroxy-2-propyl-benzoate
3,4,5-Trihydroxybenzoic acid propyl ester, Propyl gallate, Gallic acid propyl ester
n-Propilo 3,4,5 Trihidroxi Benzoato
n-Propyl 3,4,5-trihydroxybenzoate
n-Propylgallate
Propyl 3,4,5 trihydroxybenzoate
Propyl 3,4,5-trihydroxybenzoate
propyl 3,4,5-trihydroxybenzoate
Propyl 3,4,5-trihydroxybenzoate
Propyl gallate
Propyl-3,4,5-trihydroxybenzoat
propyl-3,4,5-trihydroxybenzoate
Propyl paraben
Paradept; Sodium propyl p-hydroxybenzoate; Sodium 4-Propoxycarbonylphenoxide; Natrium-4-propoxycarbonylphenoxid; 4-Propoxicarbonilfenoxido de sodio; 4-Propoxycarbonylphénolate de sodium; Solbrol P, Natriumsalz CAS NO: 35285-69-9
Propyl paraben sodium
aseptoform P bayer D 206 benzoic acid, 4-hydroxy-, propyl ester benzoic acid, p-hydroxy-, propyl ester betacide P betacine P bonomold OP chemacide PK chemocide PK p- hydroxy propyl benzoate 4- hydroxy-benzoic acid propyl ester 4- hydroxybenzoic acid N-propyl ester 4- hydroxybenzoic acid propyl ester p- hydroxybenzoic acid propyl ester para- hydroxybenzoic acid propyl ester 4- hydroxybenzoic acid propylester 4- hydroxybenzoic acid, propyl ester p- hydroxybenzoic propyl ester p- hydroxypropyl benzoate mekkings P nipagin P nipasol M nipasol P nipazol paseptol preserval P propagin propyl 4-hydroxybenzoate N- propyl 4-hydroxybenzoate propyl aseptoform propyl butex propyl chemosept propyl chemsept propyl p-hydroxybenzoate N- propyl p-hydroxybenzoate propyl para hydroxy benzoate propyl para-hydroxybenzoate N- propyl para-hydroxybenzoate propyl parabens (india) propyl parahydroxybenzoate propyl parasept propyl-p-hydroxybenzoate propyl-p-hydroxybenzoate USP/NF propylparaben N- propylparaben propylparasept protaben P solbrol P tegosept P CAS Number: 94-13-3
PROPYL P-HYDROXYBENZOATE (PROPYL PARABEN)
4-methyl-1,3-Dioxolan-2-one; 1,2-Propylene Carbonate; 1,2-Propanediol cyclic carbonate; PC; Carbonic Acid Cyclic Propylene Ester; Propylene carbonat; ene carbonate; PROPYLENE CARBONATE, 99%PROPYLENE CARBONATE, 99%PROPYLENE CARBONATE, 99%; (±)-Methyl-1,3-dioxolan-2-one; (R,S)-4-Methyl-[1,3]dioxolan-2-one; 1,2-PDC; 1,2-Propanediol carbonate; propylenesterkyselinyuhlicite CAS NO:108-32-7
Propylene carbonate
4-methyl-1,3-Dioxolan-2-one; 1,2-Propylene Carbonate; 1,2-Propanediol cyclic carbonate; PC; Carbonic Acid Cyclic Propylene Ester; (R,S)-4-Methyl-1,3-dioxolan-2-one; Cyclic propylene carbonate; Carbonic acid propylene ester; Cyclic 1,2-propylene carbonate; Propylene glycol cyclic carbonate; 1,2-Propanediol carbonate; 4-Methyl-2-oxo-1,3-dioxolane; Arconate 5000; Texacar PC CAS NO:108-32-7
PROPYLENE CARBONATE
Propylene carbonate is a cyclic carbonate that is commonly used as a solvent and as a reactive intermediate in organic synthesis.
Propylene carbonate is being considered as a potential electrochemical solvent due to its low vapor pressure, high dielectric constant and high chemical stability.
Propylene carbonate can be synthesized from propylene oxide and CO2.

CAS: 108-32-7
MF: C4H6O3
MW: 102.09
EINECS: 203-572-1

Optically active form of propylene carbonate can be prepared from the reaction between CO2 and racemic epoxides.
Decomposition of propylene carbonate on the graphite electrode in lithium batteries results in the formation of a lithium intercalated compound.
Propylene carbonate (often abbreviated PC) is an organic compound with the formula C4H6O3.
Propylene carbonate is a cyclic carbonate ester derived from propylene glycol.
This colorless and odorless liquid is useful as a polar, aprotic solvent.
Propylene carbonate is chiral, but is used as the racemic mixture in most contexts.

Clinical studies indicate that propylene carbonate does not cause skin irritation or sensitization when used in cosmetic preparations, whereas moderate skin irritation is observed when used undiluted.
No significant toxic effects were observed in rats fed propylene carbonate, exposed to the vapor, or exposed to the undiluted liquid.
In the US, propylene carbonate is not regulated as a volatile organic compound (VOC) because it does not contribute significantly to the formation of smog and because Propylene carbonate's vapor is not known or suspected to cause cancer or other toxic effects.
Propylene carbonate is an ingredient that is used in cosmetics and skincare products.
Propylene carbonate is mainly used to dissolve or suspend other ingredients in a formulation and also to decrease the thickness of formulations.

Propylene Carbonate is a PU-plasticizer and it is VOC-free clear polar solvent having high boiling and flashpoints.
Propylene Carbonate is a carbonate ester derived from propylene glycol with the peculiarity to have a low order of toxicity and a mild ether-like odor.
The product is stable under most conditions and it is not hydroscopic or corrosive.
Propylene carbonate is a VOC-exempt clear polar solvent having high boiling and
flash points, a low order of toxicity and a mild ether-like odor.
Propylene carbonate is stable under most conditions and is not hydroscopic or corrosive is particularly well suited for applications requiring a water white product or high purity.

Examples would be cosmetics, electronics or where recycling of spent material will occur.
Propylene carbonate is a cyclic carbonate that reacts with amines to form carbamates,
undergoes hydroxy alkylation and transesterification.
Propylene carbonate can be used as an isocyanate and unsaturated polyester resin cleanup solvent, viscosity reducer in coatings, CO2 extraction solvent, electrolyte in lithium batteries, polar additive for clay gellants, foundry binder catalyst, and textile dye carrier and cleaner.

Propylene Carbonate Chemical Properties
Melting point: -55 °C (lit.)
Boiling point: 240 °C (lit.)
Density: 1.204 g/mL at 25 °C (lit.)
Vapor pressure: 0.13 mm Hg ( 20 °C)
Refractive index: n20/D 1.421(lit.)
Fp: 270 °F
Storage temp.: Store below +30°C.
Solubility: 240g/l
Form: Liquid
pka: 3.92[at 20 ℃]
Specific Gravity: 1.209 (20/4℃)
Color: Clear
PH: 7.0 (200g/l, H2O, 20℃)
Relative polarity: 6
Odor: odorless
Explosive limit: 1.8-14.3%(V)
Water Solubility: 240 g/L (20 ºC)
λmax: λ: 235 nm Amax: 1.00
λ: 280 nm Amax: 0.50
λ: 300 nm Amax: 0.30
λ: 350 nm Amax: 0.05
λ: 375-400 nm Amax: 0.01
BRN: 107913
Stability: Stable.
Incompatible with strong oxidizing agents, acids, bases, reducing agents.
Protect from contact with moist air or water.
InChIKey: RUOJZAUFBMNUDX-UHFFFAOYSA-N
LogP: -0.41 at 20℃
CAS DataBase Reference: 108-32-7(CAS DataBase Reference)
NIST Chemistry Reference: Propylene carbonate(108-32-7)
EPA Substance Registry System: Propylene carbonate (108-32-7)
Propylene carbonate is a clear, colorless, mobile liquid, with a faint odor.

Uses
Propylene carbonate is used in chemical reactions as a solvent, plasticizer, solubilizer, or dilutent.
Propylene carbonate is also used in the synthesis of solar cells as well as lithium ion batteries.
Propylene carbonate is particularly well suited for applications requiring a water-white product or high purity.
Propylene carbonate can be used in cosmetics and personal care products; mainly in the formulation of make-up, primarily lipstick, eye shadow, and mascara, as well as in skin cleansing products.

Propylene carbonate is a polar, aprotic solvent used in paints and coatings and as a high-permittivity component of electrolytes in lithium batteries.
Propylene carbonate plays an important role in adhesives, paint strippers, cosmetics, plasticizer, hard surface cleaner, resin cleaner, fiberglass, polyester and polyurethane cleaner.
Furthermore, Propylene carbonate acts as a cleaner in polyurethane, a carburetor and is used in stereo lithography parts.
In electrospray ionization mass spectrometry, Propylene carbonate is doped into low surface tension solutions to enhance analyte charging.

As a solvent
Propylene carbonate is used as a polar, aprotic solvent.
Propylene carbonate has a high molecular dipole moment (4.9 D), considerably higher than those of acetone (2.91 D) and ethyl acetate (1.78 D).
Propylene carbonate is possible, for example, to obtain potassium, sodium, and other alkali metals by electrolysis of their chlorides and other salts dissolved in propylene carbonate.

Electrolyte
Due to its high relative permittivity (dielectric constant) of 64, Propylene carbonate is frequently used as a high-permittivity component of electrolytes in lithium batteries, usually together with a low-viscosity solvent (e.g. dimethoxyethane).
Propylene carbonate's high polarity allows it to create an effective solvation shell around lithium ions, thereby creating a conductive electrolyte.
However, Propylene carbonate is not used in lithium-ion batteries due to its destructive effect on graphite.
Propylene carbonate can also be found in some adhesives, paint strippers, and in cosmetics.
Propylene carbonate is also used as plasticizer.
Propylene carbonate is also used as a solvent for removal of CO2 from natural gas and synthesis gas where H2S is not also present.

Other
Propylene carbonate product may be converted to other carbonate esters by transesterification as well (see Carbonate ester#Carbonate transesterification).
In electrospray ionization mass spectrometry, propylene carbonate is doped into low surface tension solutions to increase analyte charging.
In Grignard reaction propylene carbonate (or most other carbonate esters) might be used to create tertiary alcohols.

Pharmaceutical Applications
Propylene carbonate is used mainly as a solvent in oral and topical pharmaceutical formulations.
In topical applications, propylene carbonate has been used in combination with propylene glycol as a solvent for corticosteroids.
The corticosteroid is dissolved in the solvent mixture to yield microdroplets that can then be dispersed in petrolatum.
Propylene carbonate has been used as a dispensing solvent in topical preparations.

Propylene carbonate has also been used in hard gelatin capsules as a onvolatile, stabilizing, liquid carrier.
For formulations with a low dosage of active drug, a uniform drug content may be obtained by dissolving the drug in propylene carbonate and then spraying this solution on to a solid carrier such as compressible sugar; the sugar may then be filled into hard gelatin capsules
Propylene carbonate may additionally be used as a solvent, at room and elevated temperatures, for many cellulose-based polymers and plasticizers.
Propylene carbonate is also used in cosmetics.

Purification Methods
Propylene carbonate is manufactured by reaction of 1,2-propylene oxide with CO2 in the presence of a catalyst (quaternary ammonium halide).
Contaminants include propylene oxide, carbon dioxide, 1,2-and 1,3-propanediols, allyl alcohol and ethylene carbonate.
Propylene carbonate can be purified by percolation through molecular sieves (Linde 5A, dried at 350o for 14hours under a stream of argon), followed by distillation under a vacuum.
Propylene carbonate can be stored over molecular sieves under an inert gas atmosphere.

When purified in this way Propylene carbonate contains less than 2ppm of water.
Activated alumina and dried CaO have also been used as drying agents prior to fractional distillation under reduced pressure.
Propylene carbonate has been dried with 3A molecular sieves and distilled under nitrogen in the presence of p-toluenesulfonic acid, then redistilled and the middle fraction collected.

Preparation
Although many organic carbonates are produced using phosgene, propylene and ethylene carbonates are exceptions.
They are mainly prepared by the carbonation of the epoxides (epoxypropane, or propylene oxide here):

CH3CHCH2O + CO2 → CH3C2H3O2CO

The process is particularly attractive since the production of these epoxides consumes carbon dioxide.
Thus this reaction is a good example of a green process.
The corresponding reaction of 1,2-propanediol with phosgene is complex, yielding not only propylene carbonate but also oligomeric products.
Propylene carbonate can also be synthesized from urea and propylene glycol over zinc acetate.

Synonyms
PROPYLENE CARBONATE
108-32-7
4-Methyl-1,3-dioxolan-2-one
1,2-Propylene carbonate
1,2-Propanediol cyclic carbonate
Texacar PC
1,3-Dioxolan-2-one, 4-methyl-
Cyclic propylene carbonate
Arconate 5000
1,2-Propanediol carbonate
1-Methylethylene carbonate
Cyclic 1,2-propylene carbonate
Dipropylene carbonate
1,2-Propanediyl carbonate
4-Methyldioxalone-2
Propylene glycol cyclic carbonate
Cyclic methylethylene carbonate
4-Methyl-2-oxo-1,3-dioxolane
Carbonic acid, propylene ester
Propylenecarbonate, 99%
Carbonic acid, cyclic propylene ester
NSC 11784
Propylenester kyseliny uhlicite
Carbonic acid cyclic methylethylene ester
NSC-11784
Propylene carbonate [NF]
DTXSID2026789
8D08K3S51E
Propylene carbonate (NF)
WLN: T5OVOTJ D
DTXCID006789
CAS-108-32-7
HSDB 6806
PC-HP
EINECS 203-572-1
Carbonic acid, cyclic propylene ether
4-methyl-1,3-dioxolane-2-one
Propylenester kyseliny uhlicite [Czech]
BRN 0107913
butylhexanoate
UNII-8D08K3S51E
AI3-19724
MFCD00798264
MFCD00798265
Solvenon PC
propylen carbonate
MFCD00005385
Carbonic acid propylene
Arconate propylene carbonate
EC 203-572-1
SCHEMBL15309
5-19-04-00021 (Beilstein Handbook Reference)
1-propanediol cyclic carbonate
(S)-1,2-Propanediol carbonate
CHEMBL1733973
PROPYLENE CARBONATE [II]
2-Oxo-4-methyl-1,3-dioxolane
1,2-PDC
4-methyl-[1,3]dioxolan-2-one
NSC1913
PROPYLENE CARBONATE [HSDB]
PROPYLENE CARBONATE [INCI]
PROPYLENE CARBONATE [VANDF]
NSC-1913
NSC11784
Propylene carbonate (Battery grade)
PROPYLENE CARBONATE [MART.]
Tox21_202047
Tox21_303214
BBL027518
PROPYLENE CARBONATE [USP-RS]
STL373011
AKOS009158417
Propylene Carbonate (Industrial Grade)
SB66353
Propylene carbonate, anhydrous, 99.7%
NCGC00165974-01
NCGC00165974-02
NCGC00256995-01
NCGC00259596-01
Propylene carbonate, for HPLC, 99.7%
BP-30108
BP-31155
SY008770
SY066861
DB-018081
Propylene carbonate, ReagentPlus(R), 99%
CS-0076373
FT-0602265
FT-0639979
FT-0660009
FT-0674103
P0525
D05633
EN300-296359
Propylene carbonate, anhydrous, Water 50ppm Max.
Propylene carbonate, Selectophore(TM), >=99.0%
Q415979
J-002116
Propylene carbonate, Vetec(TM) reagent grade, 98%
F0001-0165
Propylene carbonate, >=99%, acid 1,2-Propanediol cyclic carbonate, 4-Methyl-1,3-dioxolan-2-one
Propylene carbonate, United States Pharmacopeia (USP) Reference Standard
110320-40-6
PROPYLENE CARBONATE (1,2-PROPYLENE CARBONATE)
DESCRIPTION:
Propylene Carbonate (1,2-propylene Carbonate) (often abbreviated PC) is an organic compound with the formula C4H6O3.
Propylene Carbonate (1,2-propylene Carbonate) is a cyclic carbonate ester derived from propylene glycol.
Propylene Carbonate (1,2-propylene Carbonate) is useful as a polar, aprotic solvent.
Propylene Carbonate (1,2-propylene Carbonate) is chiral, but is used as the racemic mixture in most contexts.

CAS Number: 108-32-7
European Community (EC) Number: 203-572-1
Empirical Formula (Hill Notation):C4H6O3
Molecular Weight:102.09
Preferred IUPAC name: 4-Methyl-1,3-dioxolan-2-one




SYNONYMS OF PROPYLENE CARBONATE (1,2-PROPYLENE CARBONATE):
(RS)-4-Methyl-1,3-dioxolan-2-one,Cyclic propylene carbonate,Carbonic acid propylene ester,Cyclic 1,2-propylene carbonate,Propylene glycol cyclic carbonate,1,2-Propanediol carbonate,4-Methyl-2-oxo-1,3-dioxolane,Arconate 5000,Texacar PC , 1,2-Propanediol cyclic carbonate, 4-Methyl-1,3-dioxolan-2-one, Propylene carbonate,PROPYLENE CARBONATE,108-32-7
4-Methyl-1,3-dioxolan-2-one,1,2-Propylene carbonate,1,2-Propanediol cyclic carbonate,Texacar PC,Arconate 5000,Cyclic propylene carbonate,1,2-Propanediol carbonate,1,3-Dioxolan-2-one, 4-methyl-,Dipropylene carbonate,-Methylethylene carbonate,4-Methyldioxalone-2,1,2-Propanediyl carbonate,Cyclic 1,2-propylene carbonate,Propylene glycol cyclic carbonate,Cyclic methylethylene carbonate,4-Methyl-2-oxo-1,3-dioxolane,Carbonic acid, propylene ester,NSC 11784,Carbonic acid, cyclic propylene ester,Propylenester kyseliny uhlicite,HSDB 6806,Carbonic acid cyclic methylethylene ester,EINECS 203-572-1,Carbonic acid, cyclic propylene ether,NSC-11784,UNII-8D08K3S51E,BRN 0107913,DTXSID2026789,AI3-19724,8D08K3S51E,Propylenecarbonate, 99%,Propylene carbonate [NF],DTXCID006789,EC 203-572-1,5-19-04-00021 (Beilstein Handbook Reference),Propylene carbonate (NF),WLN: T5OVOTJ D,PROPYLENE CARBONATE (II),PROPYLENE CARBONATE [II],PROPYLENE CARBONATE (MART.),PROPYLENE CARBONATE [MART.],PROPYLENE CARBONATE (USP-RS),PROPYLENE CARBONATE [USP-RS],CAS-108-32-7,PC-HP,4-methyl-1,3-dioxolane-2-one,Propylenester kyseliny uhlicite,[Czech],butylhexanoate,MFCD00798264,MFCD00798265,Propylenecarbonate,Solvenon PC,propylen carbonate,?Propylene carbonate,MFCD00005385Arconate propylene carbonate,SCHEMBL15309,1-propanediol cyclic carbonate,(S)-1,2-Propanediol carbonate,CHEMBL1733973,2-Oxo-4-methyl-1,3-dioxolane,1,2-PDC,4-methyl-[1,3]dioxolan-2-one,NSC1913,1,3-dioxolane-2-one, 4-methyl,PROPYLENE CARBONATE [HSDB],PROPYLENE CARBONATE [INCI],PROPYLENE CARBONATE [VANDF],NSC-1913,NSC11784,Propylene carbonate (Battery grade),Tox21_202047,Tox21_303214,AKOS009158417,SB66353,Propylene carbonate, anhydrous, 99.7%,NCGC00165974-01,NCGC00165974-02,NCGC00256995-01,NCGC00259596-01,Propylene carbonate, for HPLC, 99.7%,BP-30108,BP-31155,SY008770,SY066861,Propylene carbonate, ReagentPlus(R), 99%,CS-0076373,FT-0602265,FT-0639979,FT-0660009,FT-0674103,NS00004305,P0525,D05633,EN300-296359,Propylene carbonate, anhydrous, Water 50ppm Max.,Propylene carbonate, Selectophore(TM), >=99.0%,Q415979,J-002116,Propylene carbonate, Vetec(TM) reagent grade, 98%,F0001-0165,Propylene carbonate, >=99%, acid


Propylene Carbonate (1,2-propylene Carbonate) is a natural product found in Solanum lycopersicum with data available.
(R)-1,2-Propylene carbonate is a chiral c1-c3 activating agent that is used as an efficient catalyst for the reaction of inorganic acids with aldehydes.
Propylene Carbonate (1,2-propylene Carbonate) can also be used to dehydrate activated esters and mismatched alkyl halides.
(R)-1,2-Propylene carbonate has been shown to activate chloride to produce reactive chlorine in organic synthesis.


Propylene Carbonate (1,2-propylene Carbonate) is a polar, aprotic solvent used in paints and coatings and as a high-permittivity component of electrolytes in lithium batteries.
Propylene Carbonate (1,2-propylene Carbonate) plays an important role in adhesives, paint strippers, cosmetics, plasticizer, hard surface cleaner, resin cleaner, fiberglass, polyester and polyurethane cleaner.

Furthermore, Propylene Carbonate (1,2-propylene Carbonate) acts as a cleaner in polyurethane, a carburetor and is used in stereo lithography parts.
In electrospray ionization mass spectrometry, it is doped into low surface tension solutions to enhance analyte charging.


Propylene Carbonate (1,2-propylene Carbonate) (PC) is a PU-plasticizer and it is VOC-free clear polar solvent having high boiling and flashpoints.
Propylene Carbonate (PC) is a carbonate ester derived from propylene glycol with the peculiarity to have a low order of toxicity and a mild ether-like odor. The product is stable under most conditions and it is not hydroscopic or corrosive




APPLICATIONS OF PROPYLENE CARBONATE (1,2-PROPYLENE CARBONATE):

Propylene Carbonate (1,2-propylene Carbonate) is a polar, aprotic solvent used in paints and coatings and as a high-permittivity component of electrolytes in lithium batteries.
Propylene Carbonate (1,2-propylene Carbonate) plays an important role in adhesives, paint strippers, cosmetics, plasticizer, hard surface cleaner, resin cleaner, fiberglass, polyester and polyurethane cleaner.
Furthermore, Propylene Carbonate (1,2-propylene Carbonate) acts as a cleaner in polyurethane, a carburetor and is used in stereo lithography parts.
In electrospray ionization mass spectrometry, it is doped into low surface tension solutions to enhance analyte charging.


Propylene Carbonate (1,2-propylene Carbonate) is particularly well suited for applications requiring a water-white product or high purity.
Propylene Carbonate (1,2-propylene Carbonate) can be used in cosmetics and personal care products; mainly in the formulation of make-up, primarily lipstick, eye shadow, and mascara, as well as in skin cleansing products.

Being a cyclic carbonate reacts with amines to form carbamates, undergoes hydroxy alkylation and transesterification PC can be used as an isocyanate and unsaturated polyester resin cleanup solvent, viscosity reducer in coatings, CO2 extraction solvent, electrolyte in lithium batteries, polar additive for clay gellants, foundry binder catalyst, and textile dye carrier and cleaner.


Solubility of Propylene Carbonate (1,2-propylene Carbonate):
Propylene Carbonate (1,2-propylene Carbonate) is Miscible with water, alcohol, ether, acetone, benzene, chloroform and ethyl acetate.









PREPARATION OF PROPYLENE CARBONATE (1,2-PROPYLENE CARBONATE):
Although many organic carbonates are produced using phosgene, propylene and ethylene carbonates are exceptions.
They are mainly prepared by the carbonation of the epoxides[5] (epoxypropane, or propylene oxide here):
CH3CHCH2O + CO2 → CH3C2H3O2CO

The process is particularly attractive since the production of these epoxides consumes carbon dioxide.
Thus this reaction is a good example of a green process.
The corresponding reaction of 1,2-propanediol with phosgene is complex, yielding not only propylene carbonate but also oligomeric products.

Propylene carbonate can also be synthesized from urea and propylene glycol over zinc acetate.

As a solvent:
Propylene Carbonate (1,2-propylene Carbonate) is used as a polar, aprotic solvent.
Propylene Carbonate (1,2-propylene Carbonate) has a high molecular dipole moment (4.9 D), considerably higher than those of acetone (2.91 D) and ethyl acetate (1.78 D).

Propylene Carbonate (1,2-propylene Carbonate) is possible, for example, to obtain potassium, sodium, and other alkali metals by electrolysis of their chlorides and other salts dissolved in propylene carbonate.

Electrolyte:
Due to its high relative permittivity (dielectric constant) of 64, it is frequently used as a high-permittivity component of electrolytes in lithium batteries, usually together with a low-viscosity solvent (e.g. dimethoxyethane).
Its high polarity allows it to create an effective solvation shell around lithium ions, thereby creating a conductive electrolyte.
However, Propylene Carbonate (1,2-propylene Carbonate) is not used in lithium-ion batteries due to its destructive effect on graphite.


Propylene Carbonate (1,2-propylene Carbonate) can also be found in some adhesives, paint strippers, and in cosmetics.
Propylene Carbonate (1,2-propylene Carbonate) is also used as plasticizer. Propylene carbonate is also used as a solvent for removal of CO2 from natural gas and synthesis gas where H2S is not also present.

This use was developed by El Paso Natural Gas Company and Fluor Corporation in the 1950s for use at the Terrell County Gas Plant in West Texas, now owned by Occidental Petroleum.

Other:
Propylene carbonate product may be converted to other carbonate esters by transesterification as well (see Carbonate ester#Carbonate transesterification).
In electrospray ionization mass spectrometry, propylene carbonate is doped into low surface tension solutions to increase analyte charging.
In Grignard reaction propylene carbonate (or most other carbonate esters) might be used to create tertiary alcohols






SAFETY INFORMATION ABOUT PROPYLENE CARBONATE (1,2-PROPYLENE CARBONATE):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product




CHEMICAL AND PHYSICAL PROPERTIES OF PROPYLENE CARBONATE (1,2-PROPYLENE CARBONATE):
Chemical formula, C4H6O3
Molar mass, 102.089 g•mol−1
Appearance, Colorless liquid
Density, 1.205 g/cm3
Melting point, −48.8 °C (−55.8 °F; 224.3 K)
Boiling point, 242 °C (468 °F; 515 K)
Solubility in water, Very soluble (240 g/L at 20°C)
Refractive index (nD), 1.4189
Structure,
Dipole moment, 4.9 D
Molecular Weight
102.09 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
XLogP3
-0.4
Computed by XLogP3 3.0 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
0
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
3
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
0
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
102.031694049 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
102.031694049 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
35.5Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
7
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
88.9
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
0
Computed by PubChem
Undefined Atom Stereocenter Count
1
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
1
Computed by PubChem
Compound Is Canonicalized
Yes
Chemical name:, 1,2-Propylene carbonate
CAS Number:, 108-32-7
Synonyms:, Propylene Carbonate (USP);
Molecular form:, C4H6O3
Appearance:, NA
Mol. Weight:, 102.09
Storage:, 2-8°C Refrigerator
Shipping Conditions:, Ambient
Water, , , <0.1%, ,
Assay, , , >98%,
Optical Rotation, , , +2 to +3,
Appearance, , , Clear colourless liquid,
Identifcation, , , GC,



PROPYLENE CARBONATE (PC)

Propylene carbonate (PC) is an organic compound with the chemical formula C4H6O3.
Propylene carbonate (PC) is a colorless to yellowish liquid with a mild odor.
Propylene carbonate is a cyclic carbonate derived from propylene oxide.
Propylene carbonate (PC) is miscible with water and many organic solvents, making it a versatile solvent in various applications.

CAS Number: 108-32-7
EC Number: 203-572-1

1,2-Propanediol carbonate, 4-Methyl-1,3-dioxolan-2-one, Carbonate de propylène, Carbonato de propileno, Carbonic acid propylene ester, Ethylene carbonate, 1-methylethylene oxide polymer, Ethylene carbonate, polymer with 1-methylethylene oxide, PC



APPLICATIONS


Propylene carbonate (PC) is commonly used as a solvent in various industries.
Propylene carbonate (PC) serves as a solvent in the formulation of paints and coatings.
Propylene carbonate (PC) is utilized as a solvent in adhesives and sealants to improve viscosity and flow properties.
Propylene carbonate (PC) is employed in the electronics industry as a solvent for electrolytes in lithium-ion batteries.

Propylene carbonate (PC) acts as a co-solvent in electrolyte formulations to enhance battery performance and stability.
In the pharmaceutical industry, PC is used as a solvent for drug formulations and delivery systems.
Propylene carbonate (PC) is employed in the production of controlled-release formulations and drug delivery matrices.

Propylene carbonate (PC) serves as a solvent for flavors and fragrances in the food and beverage industry.
Propylene carbonate (PC) is used in the production of food-grade additives and flavorings.
Propylene carbonate (PC) is utilized as a solvent in the extraction of natural compounds and essential oils.
Propylene carbonate (PC) serves as a solvent in the formulation of personal care products such as cosmetics and skincare items.

Propylene carbonate (PC) is employed in the production of hair care products, including shampoos and conditioners.
Propylene carbonate (PC) is used as a solvent in the manufacturing of cleaning products such as degreasers and detergents.
Propylene carbonate (PC) serves as a carrier solvent in the formulation of insecticides and agricultural chemicals.
Propylene carbonate (PC) is employed in the production of crop protection formulations and fertilizers.

Propylene carbonate (PC) is utilized as a solvent in gas chromatography for analytical separations.
Propylene carbonate (PC) serves as a stationary phase solvent in gas chromatography columns.
Propylene carbonate (PC) is used as a solvent for specialty chemicals and industrial intermediates.

Propylene carbonate (PC) serves as a reaction solvent in organic synthesis and polymerization reactions.
Propylene carbonate (PC) is employed in the production of plasticizers for polymer formulations.

Propylene carbonate (PC) serves as a solvent in the formulation of polyurethane coatings and resins.
Propylene carbonate (PC) is utilized in the production of specialty paints and varnishes.
Propylene carbonate (PC) serves as a solvent in the formulation of printing inks and dyes.

Propylene carbonate (PC) is employed in the production of lubricants and metalworking fluids.
Propylene carbonate (PC) serves as a solvent and carrier fluid in hydraulic fluids and industrial lubricants.

Propylene carbonate (PC) is utilized as a solvent in the formulation of electrolytes for supercapacitors and energy storage devices.
Propylene carbonate (PC) serves as a solvent for electrode materials and electrolyte additives in energy storage systems.

Propylene carbonate (PC) is employed in the production of specialty polymers and resins for advanced materials applications.
Propylene carbonate (PC) serves as a solvent and plasticizer in the production of polymeric membranes for filtration and separation processes.

Propylene carbonate (PC) is utilized as a solvent in the formulation of specialty inks for printing applications, including screen printing and digital printing.
Propylene carbonate (PC) serves as a carrier solvent in the formulation of herbicides, pesticides, and agricultural adjuvants.
Propylene carbonate (PC) is used as a solvent in the production of specialty chemicals and intermediates for pharmaceutical and agrochemical industries.

Propylene carbonate (PC) serves as a reaction solvent in chemical synthesis for the production of fine chemicals and pharmaceutical intermediates.
Propylene carbonate (PC) is employed in the production of high-performance lubricants and greases for automotive and industrial applications.
Propylene carbonate (PC) serves as a carrier solvent in the formulation of carbon dioxide (CO2) capture and sequestration technologies.

Propylene carbonate (PC) is utilized as a solvent in the formulation of cleaning agents and degreasers for industrial and household use.
Propylene carbonate (PC) serves as a solvent in the formulation of brake fluids and hydraulic fluids for automotive and aerospace applications.

Propylene carbonate (PC) is employed as a solvent in the production of specialty coatings and finishes for architectural and industrial applications.
Propylene carbonate (PC) serves as a carrier solvent in the formulation of specialty gases for semiconductor manufacturing processes.

Propylene carbonate (PC) is utilized as a solvent in the production of specialty adhesives and sealants for automotive, aerospace, and construction applications.
Propylene carbonate (PC) serves as a reaction solvent in the production of specialty polymers and copolymers for engineering plastics and elastomers.

Propylene carbonate (PC) is employed in the formulation of specialty cleaners and degreasers for electronics and precision equipment.
Propylene carbonate (PC) serves as a solvent in the formulation of heat transfer fluids and coolants for automotive and industrial applications.
Propylene carbonate (PC) is utilized as a reaction solvent in the production of specialty surfactants and emulsifiers for personal care and household products.
Propylene carbonate (PC) serves as a carrier solvent in the formulation of specialty inks and coatings for flexible packaging and printing applications.

Propylene carbonate (PC) is employed in the formulation of specialty solvents and diluents for industrial cleaning and degreasing applications.
Propylene carbonate (PC) serves as a reaction solvent in the production of specialty resins and polymers for 3D printing and additive manufacturing.

Propylene carbonate (PC) is utilized as a solvent in the formulation of specialty paints and coatings for marine and protective applications.
Propylene carbonate (PC) serves as a carrier solvent in the formulation of specialty gases and calibration standards for analytical instrumentation.
Propylene carbonate (PC) is employed in the formulation of specialty lubricants and corrosion inhibitors for marine and offshore applications.



DESCRIPTION


Propylene carbonate (PC) is an organic compound with the chemical formula C4H6O3.
Propylene carbonate (PC) is a colorless to yellowish liquid with a mild odor.
Propylene carbonate is a cyclic carbonate derived from propylene oxide.
Propylene carbonate (PC) is miscible with water and many organic solvents, making it a versatile solvent in various applications.

Propylene carbonate is used as a solvent in industries such as paints, coatings, adhesives, and electronics.
Propylene carbonate (PC) is valued for its high polarity, low toxicity, and ability to dissolve a wide range of polar and non-polar substances.
Additionally, propylene carbonate has high chemical stability and is resistant to hydrolysis and oxidation, making it suitable for use in formulations requiring long-term stability.

In addition to its use as a solvent, propylene carbonate finds applications as a reactive intermediate in organic synthesis, particularly in the production of cyclic carbonates and polycarbonates.
Propylene carbonate (PC) is also employed as a plasticizer in polymer formulations to improve flexibility and mechanical properties.

Propylene carbonate (PC) is a clear, colorless liquid with a faint odor.
Propylene carbonate (PC) is a cyclic carbonate compound with the chemical formula C4H6O3.
Propylene carbonate (PC) is soluble in water and many organic solvents, such as ethanol and acetone.
This compound has a relatively high boiling point and low vapor pressure.

Propylene carbonate (PC) is non-flammable and has low volatility under normal conditions.
Propylene carbonate (PC) is stable under ambient temperatures and pressures.
The viscosity of PC is relatively high compared to other common solvents.
Propylene carbonate (PC) is commonly used as a polar solvent in various industrial applications.

Propylene carbonate (PC) is known for its ability to dissolve a wide range of polar and non-polar substances.
Propylene carbonate (PC) exhibits good solvency power for organic compounds, salts, and some metals.
Propylene carbonate (PC) has a relatively low toxicity and is considered safe for many applications.
Propylene carbonate (PC) is used as a solvent in paints, coatings, adhesives, and electronic applications.

Propylene carbonate (PC) is also employed as a reactive intermediate in organic synthesis.
Propylene carbonate (PC) participates in various chemical reactions, including esterifications and transesterifications.
Propylene carbonate (PC) serves as a plasticizer in polymer formulations to improve flexibility and mechanical properties.

Propylene carbonate (PC) is used in lithium-ion battery electrolytes as a solvent and co-solvent.
Propylene carbonate (PC) helps improve the conductivity and stability of battery electrolyte solutions.
In pharmaceuticals, PC is used as a solvent for drug formulations and as a carrier in drug delivery systems.

Propylene carbonate (PC) is also utilized in gas chromatography as a stationary phase solvent.
Propylene carbonate (PC) has excellent thermal stability, making it suitable for high-temperature applications.
Propylene carbonate (PC) is biodegradable and environmentally friendly, with low eco-toxicity.
Propylene carbonate (PC) is regulated and approved for use in various industries by regulatory authorities.

Propylene carbonate (PC) is produced through the reaction of propylene oxide with carbon dioxide under high pressure.
Propylene carbonate (PC) undergoes purification processes to remove impurities before commercial use.
Overall, Propylene carbonate (PC) is valued for its versatile properties and wide range of applications in industry and research.



PROPERTIES


Chemical Formula: C4H6O3
Molecular Weight: 102.09 g/mol
Physical State: Clear, colorless liquid
Odor: Faint, characteristic odor
Melting Point: −48.8 °C (−55.8 °F; 224.3 K)
Boiling Point: 240.0 °C (464.0 °F; 513.2 K)
Density: 1.20 g/cm³ (at 20 °C)
Solubility in Water: Miscible
Solubility in Organic Solvents: Miscible with many organic solvents, including ethanol, acetone, and benzene
Vapor Pressure: 0.1 mmHg (20 °C)
Viscosity: 2.7 cP (at 25 °C)
Flash Point: 132 °C (270 °F; 405 K) (closed cup)
Autoignition Temperature: 455 °C (851 °F; 728 K)
Refractive Index: 1.426 (at 20 °C)
Surface Tension: 42.7 mN/m (at 20 °C)
Dielectric Constant: 64 (at 20 °C)
pH: Neutral
Heat Capacity: 209 J/(mol·K) (at 25 °C)
Heat of Vaporization: 42.92 kJ/mol
Heat of Combustion: -2284 kJ/mol
Flash Point: 132 °C (270 °F)
Flammability: Non-flammable
Acidity (pKa): 13.2 (Dipolar aprotic solvent)
Hygroscopicity: Low



FIRST AID


Inhalation:

Move the affected person to fresh air immediately.
If the person is having difficulty breathing, administer oxygen if trained to do so.
If breathing has stopped, perform artificial respiration immediately.
Seek medical attention promptly, even if symptoms seem mild.
Keep the affected person calm and reassured while awaiting medical assistance.


Skin Contact:

Remove contaminated clothing and shoes immediately.
Wash the affected area with soap and water thoroughly for at least 15 minutes.
If irritation persists, seek medical attention.
If skin irritation develops, apply a soothing cream or lotion to alleviate discomfort.
Rinse contaminated clothing and shoes thoroughly before reuse.


Eye Contact:

Flush the eyes with gently flowing lukewarm water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.
Remove contact lenses if present and easily removable after the initial flushing.
Seek immediate medical attention, even if there are no signs of discomfort or irritation.
Protect the unaffected eye from contamination while rinsing the affected eye.
Do not rub the eyes, as it may exacerbate irritation or injury.


Ingestion:

Do not induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth thoroughly with water to remove any residual chemical.
Seek immediate medical attention or contact a poison control center for further guidance.
Provide medical personnel with information about the ingested amount and time of exposure.
Do not give anything by mouth to an unconscious person.


General Measures:

Move the affected person to a well-ventilated area and provide fresh air.
Keep the person warm and calm, reassuring them while administering first aid.
Monitor vital signs such as breathing, pulse, and consciousness level.
Do not leave the affected person unattended, especially if they are experiencing symptoms.
If necessary, provide supportive measures such as oxygen therapy or cardiopulmonary resuscitation (CPR) according to trained personnel's instructions.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including chemical-resistant gloves, safety goggles or face shield, and protective clothing, when handling Propylene carbonate (PC).
Use respiratory protection, such as a dust mask or respirator, if there is a risk of inhalation of airborne particles.

Ventilation:
Work in a well-ventilated area or use local exhaust ventilation to control airborne concentrations of PC vapors.
Avoid generating aerosols or mists of PC by using handling techniques that minimize splashing or agitation.

Avoidance of Contact:
Avoid skin contact and inhalation of PC vapors or aerosols.
Use appropriate handling procedures, such as pouring or decanting, to minimize spillage and exposure.
Do not eat, drink, or smoke while handling PC, and wash hands thoroughly after handling to prevent accidental ingestion.

Spill and Leak Procedures:
Clean up spills immediately to prevent accidental exposure and environmental contamination.
Use absorbent materials, such as vermiculite or sand, to contain and absorb spilled liquid.
Avoid direct contact with spilled material and use appropriate PPE during cleanup.
Dispose of contaminated materials according to local regulations and guidelines.


Storage:

a. Container Selection:
Store Propylene carbonate (PC) in tightly sealed containers made of compatible materials, such as high-density polyethylene (HDPE) or glass.
Ensure containers are labeled with the appropriate hazard warnings and handling instructions.

b. Temperature and Humidity:
Store PC in a cool, dry, and well-ventilated area away from direct sunlight and heat sources.
Avoid exposure to high temperatures or humidity, as it may affect the stability and quality of the product.

c. Compatibility:
Keep PC away from incompatible materials, including strong acids, bases, oxidizing agents, and reducing agents.
Store away from sources of ignition or heat to prevent the risk of fire or spontaneous combustion.

d. Segregation:
Segregate PC from food, beverages, and animal feed to prevent contamination.
Store away from sources of contamination, such as pesticides, fertilizers, or other chemicals.

PROPYLENE GLYCOL
PROPYLENE GLYCOL Propylene glycol Propylene glycol (IUPAC name: propane-1,2-diol) is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste. Its chemical formula is CH3CH(OH)CH2OH. Containing two alcohol groups, it is classed as a diol. It is miscible with a broad range of solvents, including water, acetone, and chloroform. In general, glycols are non-irritating and have very low volatility.[4] It is produced on a large scale primarily for the production of polymers. In the European Union, it has E-number E1520 for food applications. For cosmetics and pharmacology, the number is E490. Propylene glycol is also present in propylene glycol alginate, which is known as E405. Propylene glycol is a compound which is GRAS (generally recognized as safe) by the US FDA (Food and Drug Administration) under 21 CFR x184.1666, and is also approved by the FDA for certain uses as an indirect food additive. Propylene glycol is approved and used as a vehicle for topical, oral, and some intravenous pharmaceutical preparations in the U.S. and in Europe. Structure The compound is sometimes called (alpha) α-propylene glycol to distinguish it from the isomer propane-1,3-diol, known as (beta) β-propylene glycol. Propylene glycol is chiral. Commercial processes typically use the racemate. The S-isomer is produced by biotechnological routes. Production Industrial Industrially, propylene glycol is mainly produced from propylene oxide (for food-grade use). According to a 2018 source, 2.16 M tonnes are produced annually.[4] Manufacturers use either non-catalytic high-temperature process at 200 °C (392 °F) to 220 °C (428 °F), or a catalytic method, which proceeds at 150 °C (302 °F) to 180 °C (356 °F) in the presence of ion exchange resin or a small amount of sulfuric acid or alkali.[5] 1,2-Propandiol Synthesis V1.svg Final products contain 20% propylene glycol, 1.5% of dipropylene glycol, and small amounts of other polypropylene glycols.[6] Further purification produces finished industrial grade or USP/JP/EP/BP grade propylene glycol that is typically 99.5% or greater. Use of USP (US Pharmacopoeia) propylene glycol can reduce the risk of Abbreviated New Drug Application (ANDA) rejection.[7] Propylene glycol can also be obtained from glycerol, a byproduct from the production of biodiesel.[4] This starting material is usually reserved for industrial use because of the noticeable odor and taste that accompanies the final product. Laboratory S-Propanediol is synthesized from via fermentation methods. Lactic acid and lactaldehyde are common intermediates. Dihydroxyacetone phosphate, one of the two products of breakdown (glycolysis) of fructose 1,6-bisphosphate, is a precursor to methylglyoxal. This conversion is the basis of a potential biotechnological route to the commodity chemical 1,2-propanediol. Three-carbon deoxysugars are also precursor to the 1,2-diol.[4] A small-scale, nonbiological route from D-mannitol is illustrated in the following scheme:[8] (s)-Propanediol from D-Mannitol.png Applications Polymers Forty-five percent of propylene glycol produced is used as a chemical feedstock for the production of unsaturated polyester resins. In this regard, propylene glycol reacts with a mixture of unsaturated maleic anhydride and isophthalic acid to give a copolymer. This partially unsaturated polymer undergoes further crosslinking to yield thermoset plastics. Related to this application, propylene glycol reacts with propylene oxide to give oligomers and polymers that are used to produce polyurethanes.[4] Propylene glycol is used in waterbased acrylic architectural paints to extend dry time which it accomplishes by preventing the surface from drying due to its slower evaporation rate compared to water. Food Propylene glycol is also used in various edible items such as coffee-based drinks, liquid sweeteners, ice cream, whipped dairy products and soda.[9][10] Vaporizers used for delivery of pharmaceuticals or personal-care products often include propylene glycol among the ingredients.[4] In alcohol-based hand sanitizers, it is used as a humectant to prevent the skin from drying.[11] Propylene glycol is used as a solvent in many pharmaceuticals, including oral, injectable, and topical formulations. Many pharmaceutical drugs which are insoluble in water utilize Propylène Glycol as a solvent and carrier; benzodiazepine tablets are one example.[12] PG is also used as a solvent and carrier for many pharmaceutical capsule preparations. Additionally, certain formulations of artificial tears use proplyene glycol as an ingredient.[13] Propylene glycol is commonly used to de-ice aircraft Antifreeze The freezing point of water is depressed when mixed with propylene glycol. It is used as aircraft de-icing fluid.[4][14] Water-propylene glycol mixtures dyed pink to indicate the mixture is relatively nontoxic are sold under the name of RV or marine antifreeze. Propylene glycol is frequently used as a substitute for ethylene glycol in low toxicity, environmentally friendly automotive antifreeze. It is also used to winterize the plumbing systems in vacant structures.[15] The eutectic composition/temperature is 60:40 propylene glycol:water/-60 °C.[16][17] The −50 °F/−45 °C commercial product is, however, water rich; a typical formulation is 40:60.[18] Electronic cigarettes liquid Propylene glycol is often used in electronic cigarettes. Along with vegetable glycerin as the main ingredient (<1–92%) in e-liquid used in electronic cigarettes, where it is aerosolized to resemble smoke. It serves as both the carrier for substances like nicotine and cannabinoids, as well as for creating a vapor which resembles smoke.[19] Miscellaneous applications A bottle of flavored e-liquid for vaping shows propylene glycol as one of the main ingredients along with vegetable glycerin. Propylene glycol (often abbreviated 'PG') has many applications. Some common applications see PG used: As a solvent for many substances, both natural and synthetic.[20] As a humectant (E1520). As a freezing point depressant for slurry ice. In veterinary medicine as an oral treatment for hyperketonaemia in ruminants.[21] In the cosmetics industry, where PG is very commonly used as a carrier or base for various types of makeup.[22] For trapping and preserving insects (including as a DNA preservative).[23] For the creation of theatrical smoke and fog in special effects for film and live entertainment. So-called 'smoke machines' or 'hazers' vaporize a mixture of PG and water to create the illusion of smoke. While many of these machines use a PG-based fuel, some use oil. Those which use PG do so in a process that is identical to how electronic cigarettes work; utilizing a heating element to produce a dense vapor. The vapor produced by these machines has the aesthetic look and appeal of smoke, but without exposing performers and stage crew to the harms and odors associated with actual smoke.[24][25] As an additive in PCR to reduce the melting temperature of nucleic acids for targeting of GC rich sequences. Safety in humans When used in average quantities, propylene glycol has no measurable effect on development and/or reproduction on animals and probably does not adversely affect human development or reproduction.[26] The safety of electronic cigarettes—which utilize PG-based preparations of nicotine or THC and other cannabinoids—is the subject of much controversy.[27][28][29] Oral administration The acute oral toxicity of propylene glycol is very low, and large quantities are required to cause perceptible health effects in humans; in fact, propylene glycol is three times less toxic than ethanol.[30] Propylene glycol is metabolized in the human body into pyruvic acid (a normal part of the glucose-metabolism process, readily converted to energy), acetic acid (handled by ethanol-metabolism), lactic acid (a normal acid generally abundant during digestion),[31] and propionaldehyde (a potentially hazardous substance).[32][33][34] According to the Dow Chemical Company, The LD50 (Lethal Dose that kills in 50% of tests) for rats is 20 g/kg (rat/oral).[35][36] Toxicity generally occurs at plasma concentrations over 4 g/L, which requires extremely high intake over a relatively short period of time, or when used as a vehicle for drugs or vitamins given intravenously or orally in large bolus doses.[37] It would be nearly impossible to reach toxic levels by consuming foods or supplements, which contain at most 1 g/kg of PG, except for alcoholic beverages in the US which are allowed 5 percent = 50g/kg.[38] Cases of propylene glycol poisoning are usually related to either inappropriate intravenous administration or accidental ingestion of large quantities by children.[39] The potential for long-term oral toxicity is also low. In an NTP continuous breeding study, no effects on fertility were observed in male or female mice that received propylene glycol in drinking water at doses up to 10,100 mg/kg bw/day. No effects on fertility were seen in either the first or second generation of treated mice.[26] In a 2-year study, 12 rats were provided with feed containing as much as 5% propylene glycol, and showed no apparent ill effects.[40] Because of its low chronic oral toxicity, propylene glycol was classified by the U. S. Food and Drug Administration as "generally recognized as safe" (GRAS) for use as a direct food additive, including frozen foods such as ice cream and frozen desserts.[38][41] The GRAS designation is specific to its use in food, and does not apply to other uses.[42] Skin, eye and inhalation contact Propylene glycol is essentially non-irritating to the skin.[43] Undiluted propylene glycol is minimally irritating to the eye, producing slight transient conjunctivitis; the eye recovers after the exposure is removed. A 2018 human volunteer study found that 10 male and female subjects undergoing 4 hours exposures to concentrations of up to 442 mg/m3 and 30 minutes exposures to concentrations of up to 871 mg/m3 in combination with moderate exercise did not show pulmonary function deficits, or signs of ocular irritation, with only slight symptoms of respiratory irritation reported.[44] Inhalation of propylene glycol vapors appears to present no significant hazard in ordinary applications.[45] Due to the lack of chronic inhalation data, it is recommended that propylene glycol not be used in inhalation applications such as theatrical productions, or antifreeze solutions for emergency eye wash stations.[46] Recently, propylene glycol (commonly alongside glycerol) has been included as a carrier for nicotine and other additives in e-cigarette liquids, the use of which presents a novel form of exposure. The potential hazards of chronic inhalation of propylene glycol or the latter substance as a whole are as-yet unknown.[47] According to a 2010 study, the concentrations of PGEs (counted as the sum of propylene glycol and glycol ethers) in indoor air, particularly bedroom air, has been linked to increased risk of developing numerous respiratory and immune disorders in children, including asthma, hay fever, eczema, and allergies, with increased risk ranging from 50% to 180%. This concentration has been linked to use of water-based paints and water-based system cleansers. However, the study authors write that glycol ethers and not propylene glycol are the likely culprit.[48][49][50] Propylene glycol has not caused sensitization or carcinogenicity in laboratory animal studies, nor has it demonstrated genotoxic potential.[51][52] Intravenous administration Studies with intravenously administered propylene glycol have resulted in LD50 values in rats and rabbits of 7 mL/kg BW.[53] Ruddick (1972) also summarized intramuscular LD50 data for rat as 13-20 mL/kg BW, and 6 mL/kg BW for the rabbit. Adverse effects to intravenous administration of drugs that use propylene glycol as an excipient have been seen in a number of people, particularly with large bolus dosages. Responses may include CNS depression, "hypotension, bradycardia, QRS and T abnormalities on the ECG, arrhythmia, cardiac arrhythmias, seizures, agitation, serum hyperosmolality, lactic acidosis, and haemolysis".[54] A high percentage (12% to 42%) of directly-injected propylene glycol is eliminated or secreted in urine unaltered depending on dosage, with the remainder appearing in its glucuronide-form. The speed of renal filtration decreases as dosage increases,[55] which may be due to propylene glycol's mild anesthetic / CNS-depressant -properties as an alcohol.[56] In one case, intravenous administration of propylene glycol-suspended nitroglycerin to an elderly man may have induced coma and acidosis.[57] However, no confirmed lethality from propylene glycol was reported. Animals Propylene glycol is an approved food additive for dog and sugar glider food under the category of animal feed and is generally recognized as safe for dogs,[58] with an LD50 of 9 mL/kg. The LD50 is higher for most laboratory animals (20 mL/kg).[59] However, it is prohibited for use in food for cats due to links to Heinz body formation and a reduced lifespan of red blood cells.[60] Heinz body formation from Propilen Glikol has not been observed in dogs, cattle, or humans. Allergic reaction Estimates on the prevalence of propylene glycol allergy range from 0.8% (10% propylene glycol in aqueous solution) to 3.5% (30% propylene glycol in aqueous solution).[61][62][63] The North American Contact Dermatitis Group (NACDG) data from 1996 to 2006 showed that the most common site for propylene glycol contact dermatitis was the face (25.9%), followed by a generalized or scattered pattern (23.7%).[61] Investigators believe that the incidence of allergic contact dermatitis to propylene glycol may be greater than 2% in patients with eczema or fungal infections, which are very common in countries with lesser sun exposure and lower-than-normal vitamin D balances. Therefore, propylene glycol allergy is more common in those countries.[64] Because of its potential for allergic reactions and frequent use across a variety of topical and systemic products, propylene glycol was named the American Contact Dermatitis Society's Allergen of the Year for 2018.[65][66] Recent publication from The Mayo Clinic reported 0.85% incidence of positive patch tests to propylene glycol (100/11,738 patients) with an overall irritant rate of 0.35% (41/11,738 patients) during a 20-year period of 1997–2016.[67] 87% of the reactions were classified as weak and 9% as strong. The positive reaction rates were 0%, 0.26%, and 1.86% for 5%, 10%, and 20% propylene glycol respectively, increasing with each concentration increase. The irritant reaction rates were 0.95%, 0.24%, and 0.5% for 5%, 10%, and 20% propylene glycol, respectively. Propylene glycol skin sensitization occurred in patients sensitive to a number of other concomitant positive allergens, most common of which were: Myroxylon pereirae resin, benzalkonium chloride, carba mix, potassium dichromate, neomycin sulfate; for positive propylene glycol reactions, the overall median of 5 and mean of 5.6 concomitant positive allergens was reported. Environmental Propylene glycol occurs naturally, probably as the result of anaerobic catabolism of sugars in the human gut. It is degraded by vitamin B12-dependent enzymes, which convert it to propionaldehyde.[68] Propylene glycol is expected to degrade rapidly in water from biological processes, but is not expected to be significantly influenced by hydrolysis, oxidation, volatilization, bioconcentration, or adsorption to sediment.[69] Propylene glycol is readily biodegradable under aerobic conditions in freshwater, in seawater and in soil. Therefore, propylene glycol is considered as not persistent in the environment. Propylene glycol exhibits a low degree of toxicity toward aquatic organisms. Several guideline studies available for freshwater fish with the lowest observed effect concentration of 96-h LC50 value of 40,613 mg/l in a study with Oncorhynchus mykiss. Similarly, the effect concentration determined in marine fish is a 96-h LC50 of >10,000 mg/l in Scophthalmus maximus. Propylene Glycol in Food: Is This Additive Safe? Propylene glycol is a substance commonly used as a food additive or ingredient in many cosmetic and hygiene products. The US and European food authorities have declared it as generally safe for use in foods. However, it has become controversial since it is also an ingredient in antifreeze. This had led to health concerns about possible toxic effects from eating foods that contain it. This article investigates what propylene glycol is, why it is used and whether it is dangerous to your health. What Is Propylene Glycol? Propylene glycol is a synthetic food additive that belongs to the same chemical group as alcohol. It is a colorless, odorless, slightly syrupy liquid that is a bit thicker than water. It has practically no taste (1Trusted Source). Additionally, it can dissolve some substances better than water and is also good at retaining moisture. This makes it very useful as a food additive, so it can be found in a wide variety of processed foods and drinks (2). Other names it is known by include (2): 1,2-propanediol 1,2-dihydroxypropane Methyl ethyl glycol Trimethyl glycol Propylene glycol is sometimes confused with ethylene glycol, as both have been used in antifreeze due to their low melting points. However, these are not the same substance. Ethylene glycol is highly toxic to humans and is not used in food products. SUMMARY Propylene glycol is a synthetic, colorless, odorless, tasteless liquid that belongs to the same chemical class as alcohol. It should not be confused with the toxic substance ethylene glycol. Where and How Is It Used? Propylene glycol is commonly used as an additive to aid in the processing of foods and improve their texture, flavor, appearance and shelf life. In foods, propylene glycol may be used in the following ways (3, 4, 5): Anti-caking agent: It helps prevent food components from sticking to one another and forming clumps, such as in dried soups or grated cheese. Antioxidant: It extends the shelf life of foods by protecting them against deterioration caused by oxygen. Carrier: It dissolves other food additives or nutrients to be used in processing, such as colors, flavors or antioxidants. Dough strengthener: It modifies the starches and gluten in dough to make it more stable. Emulsifier: It prevents food ingredients from separating, such as oil and vinegar in salad dressing. Moisture preserver: It helps foods maintain a stable level of moisture and stops them from drying out. Examples include marshmallows, coconut flakes and nuts. Processing aid: It is used to enhance the appeal or the use of a food, for example, to make a liquid clearer. Stabilizer and thickener: It can be used to hold food components together or thicken them during and after processing. Texturizer: It can change the appearance or mouthfeel of a food. Propylene glycol is commonly found in many packaged foods, such as drink mixes, dressings, dried soups, cake mix, soft drinks, popcorn, food coloring, fast foods, bread and dairy products (6Trusted Source). It is also used in injectable medications, like lorazepam, and in some creams and ointments that are applied to the skin, such as corticosteroids (2, 7Trusted Source). Due to its chemical properties, it is also found in a wide variety of hygiene and cosmetic products. Additionally, it is used in industrial products like paint, antifreeze, artificial smoke and e-cigarettes (2, 6Trusted Source). SUMMARY Propylene glycol is commonly used as a food additive. It helps preserve moisture as well as dissolve colors and flavors. It is also used in some medications, cosmetic products, antifreeze and other industrial products. Is Propylene Glycol in Food Dangerous? Propylene glycol is “generally recognized as safe” (GRAS) by the US Food and Drug Administration (FDA) (8). In the US, it can be used as a direct and indirect food additive. In Europe, it is only allowed to be used in food as a solvent for colors, emulsifiers, antioxidants and enzymes, with up to 0.45 grams per pound (1 gram/kg) allowed in the final food product (9Trusted Source). The World Health Organization recommends a maximum intake of 11.4 mg of propylene glycol per pound of body weight (25 mg/kg) per day. The estimated exposure to propylene glycol through foods in the US is 15 mg per pound (34 mg/kg) per day (9Trusted Source). In comparison, one person who developed symptoms of toxicity was receiving 213 grams of propylene glycol per day. For a 120-pound (60-kg) adult, that is over 100 times what is found in the average diet (9Trusted Source). There is only one documented case of toxicity caused by food. A man drank very large amounts of cinnamon whiskey containing propylene glycol and was found unconscious. While his symptoms were also due to the alcohol, some could be attributed to the propylene glycol (10Trusted Source). Overall, apart from people with allergies and one case of excessive consumption, there have been no other reported cases of negative or toxic effects of propylene glycol in foods. However, as current intakes are estimated to be above the recommended level, it may be wise to reduce dietary sources where you can, especially as the primary sources are highly processed foods. SUMMARY Propylene glycol is considered generally safe by US and European authorities. There is only one documented case of toxicity caused by excessive alcohol intake. It is recommended to limit intake to 11.4 mg per pound (25 mg/kg) of body weight per day. Health Effects of Propylene Glycol There is a lot of conflicting information about the dangers of propylene glycol. Some websites state it is safe, while others claim it causes heart attacks, kidney and liver failure and brain problems. How Toxic Is Propylene Glycol? The toxicity of propylene glycol is very low. It has not been found to cause cancer, damage genes or interfere with fertility or reproduction. Moreover, there are no reported deaths on record (1Trusted Source, 9Trusted Source). In rats, the median lethal dose is 9 grams per pound (20 g/kg). Compare this to sugar, which has a lethal dose of 13.5 grams per pound (29.7 g/kg), or salt, which is just 1.4 grams per pound (3 g/kg) in rats (11, 12, 13). After ingesting a food containing propylene glycol, about 45% of it will be excreted by the kidneys unchanged. The rest is broken down in the body into lactic acid (1Trusted Source, 14). When consumed in toxic quantities, the buildup of lactic acid can lead to acidosis and kidney failure. Acidosis occurs when the body cannot get rid of the acid fast enough. It begins to build up in the blood, which interferes with proper functioning (10Trusted Source). The main sign of toxicity is central nervous system depression. Symptoms include a slower rate of breathing, decreased heart rate and loss of consciousness (14). Cases of poisoning may be treated with hemodialysis to remove the substance from the blood or by removing the drug or substance that contains propylene glycol (15Trusted Source). However, toxicity is very rare. Most cases resulted from the use of very high doses of medication containing propylene glycol or unusual circumstances, such as one man who was ill and drank the contents of an ice pack (16Trusted Source, 17Trusted Source). SUMMARY Propylene glycol has very low toxicity. Poisoning rarely occurs, and it is typically due to high doses of medications that contain it. Dangers for People With Kidney or Liver Disease In adults with normal liver and kidney function, propylene glycol is broken down and removed from the blood fairly quickly. On the other hand, in people with kidney disease or liver disease, this process may not be as efficient. This can lead to a buildup of propylene glycol and lactic acid in the bloodstream, causing symptoms of toxicity (9Trusted Source, 15Trusted Source). Additionally, because there is no maximum dose limit for propylene glycol used in drugs, it is possible to receive very high doses in some circumstances (9Trusted Source). One woman with kidney damage was treated for short breath and throat swelling with lorazepam. She received 40 times the recommended level of propylene glycol over 72 hours, resulting in acidosis and other symptoms of toxicity (18Trusted Source). Critically ill patients often have impaired kidney or liver function and may also have an increased risk from prolonged or high-dose drug treatments. For example, in one study, 19% of critical patients being treated with the drug lorazepam were observed to have signs of propylene glycol toxicity (19Trusted Source). For people with kidney and liver disease, drug alternatives without propylene glycol may be used if needed. There is no evidence that dietary amounts are cause for concern. SUMMARY People with kidney or liver damage are not able to clear propylene glycol or lactic acid from the blood as effectively as healthy people. When receiving very high doses of it in medications, they have an increased risk of developing toxicity. Dangers for Infants and Pregnant Women Pregnant women, children and infants under four years of age have lower levels of an enzyme known as alcohol dehydrogenase. This enzyme is essential for the breakdown of propylene glycol Therefore, these groups may be at risk of developing toxicity if they are exposed to large amounts through medication. Infants are at particular risk. They take up to three times as long to remove propylene glycol from their bodies and may be particularly sensitive to the effects on the central nervous system (9Trusted Source, 20Trusted Source, 21Trusted Source). There are case reports of premature infants injected with large doses of vitamins containing propylene glycol that resulted in seizures (22Trusted Source, 23Trusted Source). However, another study demonstrated that doses of up to 15.4 mg per pound (34 mg/kg) of propylene glycol over 24 hours were tolerated by young babies (24Trusted Source). While these populations may be at increased risk of toxicity in the case of very high exposure from medication, there is no research indicating any harm from the amounts found in the diet. SUMMARY Young children and infants are not able to process propylene glycol as effectively as adults. Therefore, they are at risk of it building up in their bodies and developing symptoms of toxicity when exposed to high doses in medications. Risk of Heart Attack Some websites claim that propylene glycol increases the risk of heart disease and heart attacks. It is true that when propylene glycol is injected in high amounts or too quickly, a drop in blood pressure and heart rhythm problems can occur (20Trusted Source). Animal studies also demonstrate that very high doses of propylene glycol can rapidly decrease heart rate, cause low blood pressure and even cause the heart to stop (25Trusted Source, 26Trusted Source). In one report, an 8-month-old child suffered loss of heart function and subsequent brain damage after being treated with silver sulfadiazine cream that contained propylene glycol. The cream was used for treating burns that covered 78% of his body (27Trusted Source). In this case, the child received 4.1 grams per pound (9 g/kg) of propylene glycol, which is a very high dose. In another case, a 15-month-old child was given oral doses of vitamin C dissolved in propylene glycol. He developed symptoms of toxicity, including non-responsiveness and irregular heart rhythms, but recovered after the vitamin solution was stopped (28Trusted Source). While these reports may be concerning, it is important to note that in both these cases, toxicity occurred due to a high dosage of medication in a vulnerable age group. The most common skin reaction, or dermatitis, is the development of a rash on the face or in a generalized scattered pattern over the body (32Trusted Source). Systemic dermatitis has been reported after eating foods and taking medications and intravenous drugs that contain propylene glycol (33Trusted Source, 34Trusted Source, 35). One study of 38 sensitive people given propylene glycol by mouth found that 15 of them developed a rash within 3 to 16 hours (31Trusted Source). In addition, propylene glycol can cause irritant contact dermatitis. In this case, a rash may develop in sensitive people when their skin comes into contact with products that contain it, such as shampoo or moisturizer (6Trusted Source). People who already have skin conditions or sensitive skin are at particular risk of contact allergy to this additive (6Trusted Source). For people with allergic dermatitis, it is best to avoid all sources of propylene glycol. For contact dermatitis, avoid products containing it that come into contact with the skin. SUMMARY Between 0.8 and 3.5% of people are allergic to propylene glycol. Common symptoms include a rash on the face or body. How Can You Avoid It? While propylene glycol is generally considered safe, you may still choose to avoid it if you are allergic or you simply want to reduce your intake. It is found in many different food products and can be identified by checking the ingredients list. The names it may be listed under include: Propylene glycol Propylene glycol mono and diester E1520 or 1520 Common foods include soft drinks, marinades and dressings, cake mix, frosting, popcorn, food coloring, fast foods, bread and dairy products (6Trusted Source, 35). Unfortunately, if propylene glycol is used as a carrier or solvent for another additive, such as flavor or color instead of a direct ingredient, it may not be listed on the food label (36). However, the majority of foods containing it are highly processed junk foods. By consuming a fresh, healthy, whole foods diet, you can avoid most sources without too much trouble. You can also check the labels of cosmetic products, though avoiding it may be difficult. There are several helpful websites that can help you identify which products contain it. If you have an allergy to propylene glycol, it is important to let your doctor or pharmacist know about it before taking certain medications. An alternative can usually be found. SUMMARY To avoid propylene glycol in foods, read labels and look for it as an ingredient or as the additive number E1520. Use online sources to help identify hygiene products that contain it. For medications, ask your doctor or pharmacist. The Bottom Line Propylene glycol is a useful chemical found in a wide variety of products across the food, drug, cosmetic and manufacturing industries. While there are cases of toxicity from very high doses of medication, it is overall considered a very low-toxicity substance. A small percentage of people are allergic to propylene glycol and may need to avoid products containing it. Yet for most people, the amounts regularly found in food products are considered safe. Keep in mind that most of the foods containing propylene glycol are highly processed junk foods. A fresh, whole foods diet will naturally contain lower amounts of this additive. Propylene glycol is a synthetic liquid substance that absorbs water. Propylene glycol is also used to make polyester compounds, and as a base for deicing solutions. Propylene glycol is used by the chemical, food, and pharmaceutical industries as an antifreeze when leakage might lead to contact with food. The Food and Drug Administration (FDA) has classified propylene glycol as an additive that is “generally recognized as safe” for use in food. It is used to absorb extra water and maintain moisture in certain medicines, cosmetics, or food products. It is a solvent for food colors and flavors, and in the paint and plastics industries. Propylene glycol is also used to create artificial smoke or fog used in fire-fighting training and in theatrical productions. Other names for propylene glycol are 1,2-dihydroxypropane, 1,2-propanediol, methyl glycol, and trimethyl glycol. Propylene glycol is clear, colorless, slightly syrupy liquid at room temperature. It may exist in air in the vapor form, although propylene glycol must be heated or briskly shaken to produce a vapor. Propylene glycol is practically odorless and tasteless.
PROPYLENE GLYCOL DICAPRYLATE
Chem/IUPAC Name: Decanoic acid, mixed diesters with octanoic acid and propylene glycol, N° CAS : 68583-51-7 / 58748-27-9 / 68988-72-7, synonyme : PGDI, Inci : Propyleneglycol dicaprylate / dicaprate, Cas : 68583-51-7, EC : 271-516-3, Emollient : Adoucit et assouplit la peau
PROPYLENE GLYCOL DICAPRYLATE DICAPRATE
PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE propylene glycol dicaprylate/dicaprate Rating: GOOD Categories: Uncategorized Gel-textured ingredient used in many lightweight moisturizers. It’s a mix of propylene glycol and capric acid, a fatty acid derived from plants. Propylene Glycol Dicaprylate/Dicaprate Propylene Glycol Dicaprylate/Dicaprate is classified as : Emollient CAS Number of Propylene Glycol Dicaprylate/Dicaprate: 68583-51-7 / 58748-27-9 / 68988-72-7 EINECS/ELINCS No of Propylene Glycol Dicaprylate/Dicaprate: 271-516-3 COSING REF No of Propylene Glycol Dicaprylate/Dicaprate: 78795 Chem/IUPAC Name of Propylene Glycol Dicaprylate/Dicaprate: Decanoic acid, mixed diesters with octanoic acid and propylene glycol Propylene Glycol Dicaprylate/Dicaprate What Is Propylene Glycol Dicaprylate/Dicaprate? Propylene Glycol Isostearate, Propylene Glycol Laurate, Propylene Glycol Myristate, Propylene Glycol Oleate and Propylene Glycol Oleate SE are monoesters of propylene glycol and fatty acids. SE indicates that it is a self-emulsifying form that contains some sodium and/or potassium oleate. Propylene Glycol Dicaprylate, Propylene Glycol Dicaprylate/Dicaprate, Propylene Glycol Dicocoate, Propylene Glycol Dipelargonate, Propylene Glycol Oleate, Propylene Glycol Dicaprate, Propylene Glycol Diisostearate and Propylene Glycol Dilaurate are diesters of proplyene glycol and fatty acids. The use of the "/" in the name indicates that the ingredient is a mixture of Propylene Glycol Dicaprylate and Propylene Glycol Dicaprate. In cosmetics and personal care products, Propylene Glycol monoesters and diesters are used in the formulation of moisturizers, cleansing products, fragrance products, and makeup products such as foundations and lipsticks. Why is Propylene Glycol Dicaprylate/Dicaprate used in cosmetics and personal care products? The following functions have been reported for these ingredients. Skin conditioning agent - emollient - Propylene Glycol Oleate, Propylene Glycol Isostearate, Propylene Glycol Laurate, Propylene Glycol Myristate Skin conditioning agent - occlusive - Propylene Glycol Dicaprate, Propylene Glycol Dicaprylate, Propylene Glycol Dicaprylate/Dicaprate, Propylene Glycol Dicocoate, Propylene Glycol Diisostearate, Propylene Glycol Dilaurate, Propylene Glycol Dioleate, Propylene Glycol Dipelargonate Surfactant - emulsifying agent - Propylene Glycol Oleate, Propylene Glycol Oleate SE, Propylene Glycol Isostearate, Propylene Glycol Laurate, Propylene Glycol Myristate Viscosity increasing agent - nonaqueous - Propylene Glycol Dicaprate, Propylene Glycol Dicaprylate, Propylene Glycol Dicocoate, Propylene Glycol Diisostearate, Propylene Glycol Dilaurate, Propylene Glycol Dioleate, Propylene Glycol Dipelargonate Scientific Facts: Propylene glycol monoesters and diesters are typically produced from the reaction of propylene glycol with the corresponding fatty acid. For example, Propylene Glycol Oleate is produced via the reaction of propylene glycol with oleic acid. Propylene Glycol Dicaprylate/Dicaprate * A skin-conditioning agent Propylene Glycol Dicaprylate/Dicaprate is derived from Propylene Glycol, and is a diester of proplyene glycol and fatty acids; it is a mixture of Propylene Glycol Dicaprylate and Propylene Glycol Dicaprate (CosmeticsInfo.org). However, this compound differs greatly from Propylene Glycol, and is strictly a skin conditioning agent that utilizes its fatty acid components to maintain and improve lubrication and skin cell resilience, combining with proteins to promote healthy skin, according to research. Propylene Glycol Dicaprylate/Dicaprate is used in skin care and beauty products as an ingredient in moisturizers, cleansing products, fragrance products, and makeup products such as foundations and lipsticks. * A skin-conditioning agent Functions of Propylene Glycol Dicaprylate/Dicaprate: Propylene Glycol Dicaprylate/Dicaprate is derived from Propylene Glycol, and is a diester of proplyene glycol and fatty acids; it is a mixture of Propylene Glycol Dicaprylate and Propylene Glycol Dicaprate (CosmeticsInfo.org). However, this compound differs greatly from Propylene Glycol, and is strictly a skin conditioning agent that utilizes its fatty acid components to maintain and improve lubrication and skin cell resilience, combining with proteins to promote healthy skin, according to research. Propylene Glycol Dicaprylate/Dicaprate is used in skin care and beauty products as an ingredient in moisturizers, cleansing products, fragrance products, and makeup products such as foundations and lipsticks. Propylene Glycol Dicaprylate/Dicaprate is FDA approved as a direct food additive, and CIR approved as well. Safety Measures/Side Effects of Propylene Glycol Dicaprylate/Dicaprate: According to the Cosmetics Database, Propylene Glycol Dicaprylate/Dicaprate is a moderate hazard ingredient. Skin irritation studies reviewed by the CIR Expert Panel found that Propylene Glycol Dicaprylate/Dicaprate caused minimal to no irritation, and negative comedogenicity results. "Data on the fatty acids and propylene glycol were negative for mutagenicity, chronic toxicity, and skin irritation and sensitizaiton" However, Propylene Glycol Dicaprylate/Dicaprate is considered a penetration enhancer and may enhance the skin penetration of other chemicals. Users should exercise caution when using products and formulas that contain this ingredient when combined with other ingredients for which limits have been set based on low dermal absorption. The Propylene Glycol Dicaprylate family of ingredients includes several esters and diesters of Propylene Glycol and fatty acids. These ingredients are used in cosmetic formulations as skin conditioning agents, viscosity increasing agents, and surfactants. Two skin irritation studies (minimal to no irritation) and a comedogenicity study (insignificant comedogen) on Propylene Glycol Dicaprylate/Dicaprate and a skin irritation study (slight) and an acute oral toxicity study (nontoxic) on Propylene Glycol Laurate were available. Available data were also found indicating that Propylene Glycol Dicaprylate/Dicaprate and Propylene Glycol Dipelargonate may enhance the skin penetration of other chemicals. Because of the ability of these Polyethylene Glycol esters and diesters to enhance penetration of other agents, it was recommended that care be taken in using these and other Polyethylene Glycol esters and diesters in cosmetic products. Previous Cosmetic Ingredient Review safety assessments of related ingredients, including Polyethylene Glycol, Polyethylene Glycol Stearate, Coconut Oils and Acids, Isostearic Acid, Lauric Acid, Myristic Acid, Oleic Acid, and Caprylic/Capric Triglyceride, were summarized. Included were mutagenicity, chronic toxicity, and skin irritation and sensitization data. Based in part on the limited data available on the ingredients included in the report, but more so on the previous reviews of chemically similar moieties, it was concluded that Propylene Glycol Dicaprylate, Propylene Glycol Dicaprylate/Dicaprate, Propylene Glycol Dicocoate, Propylene Glycol Dipelargonate, Propylene Glycol Isostearate, Propylene Glycol Laurate, Propylene Glycol Myristate, Propylene Glycol Oleate, Propylene Glycol Oleate SE, Propylene Glycol Dioleate, Propylene Glycol Dicaprate, Propylene Glycol Diisostearate, and Propylene Glycol Dilaurate are safe. Propylene Glycol Dicaprylate/Dicaprate Propylene Glycol Dicaprylate/Dicaprate (CAS Nos. 58748- 27-9 ; 9062-04-8; and 68988-72-7) is a mixture of the propylene glycol diesters of caprylic and capric acids The structures of Propylene Glycol Dicaprylate and Propylene Glycol Dicaprate appear on the preceding page. Propylene Glycol Dicaprylate/Dicaprate is also defined as the propylene glycol diester of short chain, predominantly naturally derived C8-Clo fatty acids . It is soluble in alcohol containing up to 20% water and its viscosity is usually low . Other names for this mixture include: Decanoic Acid, 1-Methyl-1,2-Ethanediyl Ester mixed with 1-Methyl-1,2-Ethanediyl Dioctanoate; Decanoic Acid, Mixed Diesters with Octanoic Acid and Propylene Glycol ; Caprylic, Capric Acid, Propylene Glycol Diester; Propylene Glycol Dicaprate-Caprate; and Propylene Glycol, Caprylate Caprate Dieste Propylene Glycol Dicaprylate/Dicaprate has also been defined as the propylene glycol diester of saturated vegetable acids (C8-ClO chain length) that contains 65 to 80% caprylic acid and 15 to 30% capric acid Details Propylene Glycol Dicaprylate/Dicaprate is an emollient that leaves a light, non-oily smooth and velvet skin sensation. According to manufacturer info it's also great at dispersing and dissolving pigments and sunscreen actives. Most often you will meet this guy in light moisturizers, sunscreens or makeup products. Properties Related Categories Analytical Standards, Analytical/Chromatography, Pharmacopeia & Metrological Institutes Standards, USP Standards, USP Standards P - R Less... grade pharmaceutical primary standard mfr. no. USP Featured Industry Pharmaceutical (small molecule) InChI 1S/C10H20O2.C8H16O2.C3H8O2/c1-2-3-4-5-6-7-8-9-10(11)12;1-2-3-4-5-6-7-8(9)10;1-3(5)2-4/h2-9H2,1H3,(H,11,12);2-7H2,1H3,(H,9,10);3-5H,2H2,1H3 InChI key YZWQUQVFVLJWCS-UHFFFAOYSA-N Description General description This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. Analysis Note Propylene Glycol Dicaprylate/Dicaprate are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. ​ Molecular Weight of Propylene Glycol Dicaprylate/Dicaprate: 328.5 g/mol XLogP3-AA of Propylene Glycol Dicaprylate/Dicaprate: 6.4 Hydrogen Bond Donor Count of Propylene Glycol Dicaprylate/Dicaprate: 0 Hydrogen Bond Acceptor Count of Propylene Glycol Dicaprylate/Dicaprate: 4 Rotatable Bond Count of Propylene Glycol Dicaprylate/Dicaprate: 17 Exact Mass of Propylene Glycol Dicaprylate/Dicaprate: 328.26136 g/mol Monoisotopic Mass of Propylene Glycol Dicaprylate/Dicaprate: 328.26136 g/mol Topological Polar Surface Area of Propylene Glycol Dicaprylate/Dicaprate: 52.6 Ų Heavy Atom Count of Propylene Glycol Dicaprylate/Dicaprate:23 Formal Charge of Propylene Glycol Dicaprylate/Dicaprate: 0 Complexity of Propylene Glycol Dicaprylate/Dicaprate: 302 Isotope Atom Count of Propylene Glycol Dicaprylate/Dicaprate: 0 Defined Atom Stereocenter Count of Propylene Glycol Dicaprylate/Dicaprate: 0 Undefined Atom Stereocenter Count of Propylene Glycol Dicaprylate/Dicaprate: 1 Defined Bond Stereocenter Count of Propylene Glycol Dicaprylate/Dicaprate: 0 Undefined Bond Stereocenter Count of Propylene Glycol Dicaprylate/Dicaprate: 0 Covalently-Bonded Unit Count of Propylene Glycol Dicaprylate/Dicaprate: 1 Compound of Propylene Glycol Dicaprylate/Dicaprate Is Canonicalized : Yes
PROPYLENE GLYCOL ISOSTEARATE
Propylene Glycol Isostearate is an ester of propylene glycol and isostearic acid.
Propylene Glycol Isostearate is a white to cream-colored soft waxy solid with a slightly fatty odor and taste.


CAS Number: 68171-38-0 / 63799-53-1
EC Number: 269-027-5
MDL Number: MFCD00152773
Chem/IUPAC Name: Isooctadecanoic acid, monoester with propane-1,2-diol
Molecular Formula: C21 H42 O3



1,2-Propandiol,Propylenglykol, ISOOCTADECANOIC ACID, MONOESTER WITH 1,2-PROPANEDIOL, MONOESTER WITH 1,2-PROPANEDIOL ISOOCTADECANOIC ACID, PROPYLENE GLYCOL ISOSTEARATE, and PROPYLENE GLYCOL MONOISOSTEARATE, CAS number: 68171-38-0 / 63799-53-1, Isooctadecanoic acid, monoester with propane-1,2-diol,



Propylene Glycol Isostearate is an ester of propylene glycol and isostearic acid.
Isostearic acid is a lightly chained liquid fatty acid obtained from natural sources like vegetable oils.
Propylene Glycol Isostearate is a synthetic compound formed from propylene glycol and stearic acid.


Propylene Glycol Isostearate is a white to cream-colored soft waxy solid with a slightly fatty odor and taste.
Stearic acid is a naturally occurring fatty acid found in animal and vegetable oils.
Propylene Glycol Isostearate is an ester of propylene glycol and Isostearic Acid (q.v.).


Propylene Glycol Isostearate's HLB value is 3.
Propylene Glycol Isostearate is suitable for hot processes and is ideally added to the oil phase, the recommended usage range is 0.5 - 4.0%.
Propylene Glycol Isostearate is made from RSPO-certified, sustainable palm oil and has a Natural Origin Index (ISO 16128) of 0.83.
Propylene Glycol Isostearate is a mixture of propylene glycol and isostearic acid.



USES and APPLICATIONS of PROPYLENE GLYCOL ISOSTEARATE:
Propylene Glycol Isostearate is used as an emollient, humectant, emulsifier, and surfactant in cosmetic products.
As Propylene Glycol Isostearate is apparent both Propylene glycol and isostearic acid individually are very good in terms of skincare. PG can act as a humectant.


Propylene Glycol Isostearate draws water from water vapor present in the air and moisturizes the skin.
Propylene Glycol Isostearate can be used in all skin types, especially on normal and mild dry skin types.
Propylene Glycol Isostearate helps in retaining moisture in the skin. Isostearic acid is a fatty acid and it also acts as an emollient.


Propylene Glycol Isostearate fills up the gaps in between the top layer cells in the skin.
Propylene Glycol Isostearate makes skin appear smoother and tighter.
Propylene Glycol Isostearate forms a thin protective barrier on the surface of the skin and protects it from any allergen or bacteria which may compromise with skin’s health otherwise.


As a surfactant, Propylene Glycol Isostearate carries both a water-loving group PG and a fat-loving group- isostearate.
The oil/ fat-loving group attracts dirt, impurities and attaches them to the surfactant molecule whereas because of the water-loving part Propylene Glycol Isostearate can be carried away with water and becomes cleaner.


With the same principle, Propylene Glycol Isostearate also acts as an emulsifier and prevents separation of the components, and enables even distribution of the product components when used.
Propylene Glycol Isostearate is used in formulations of creams, lotions, gels, shampoos, conditioners, sun care products, and other hair and skincare products.


In addition to its use in cosmetic products, Propylene Glycol Isostearate is also used in food processing like margarine.
Propylene Glycol Isostearate functions as a self-emulsifying agent in cosmetic products.
Propylene Glycol Isostearate is designed for use in face/neck care, body care, colour cosmetics and cleansers.


Propylene Glycol Isostearate comes in pellet form and has a melting point of 41°C.
Propylene Glycol Isostearate is used in cosmetic formulations.
Propylene Glycol Isostearate acts as an emollient (makes the skin smooth and supple).
Cosmetic Uses of Propylene Glycol Isostearate: skin conditioning and surfactants.



FUNCTIONS OF PROPYLENE GLYCOL ISOSTEARATE IN COSMETIC PRODUCTS:
*SKIN CONDITIONING:
Propylene Glycol Isostearate maintains the skin in good condition

*SURFACTANT - CLEANSING:
Surface-active agent to clean skin, hair and / or teeth



FUNCTIONS OF PROPYLENE GLYCOL ISOSTEARATE:
*SKIN CONDITIONER:
Propylene Glycol Isostearate keeps the skin in good condition.

*SURFACTANT – CLEANSER:
Propylene Glycol Isostearate wets body surfaces, emulsifies or solubilizes oils and suspends dirt (generally, these ingredients contribute to the soap and foaming properties of cleaning products).



WHAT DOES PROPYLENE GLYCOL ISOSTEARATE DO IN A FORMULATION?
*Skin conditioning
*Surfactant



WHAT IS PROPYLENE GLYCOL ISOSTEARATE USED FOR?
Here are its main functions:
*Attracts water:
Zeichner says at low concentrations, propylene glycol acts like a humectant, which means Propylene Glycol Isostearate binds water and pulls in hydration to the outer skin layer.
When used in cosmetic products, Propylene Glycol Isostearate helps give the skin a hydrated, dewy appearance.



FUNCTIONS OF PROPYLENE GLYCOL ISOSTEARATE:
*Skin care agent:
Propylene Glycol Isostearate maintains skin in good condition
*Surfactant:
Propylene Glycol Isostearate reduces the surface tension of cosmetics and contributes to the uniform distribution of the product during use



FUNCTIONAL GROUP OF PROPYLENE GLYCOL ISOSTEARATE:
*Base ingredients
*Active ingredients
*Preservatives
*UV filters
*Dyes
*Fragrances



FEATURES OF PROPYLENE GLYCOL ISOSTEARATE:
W/O emulsifier, an ingredient enabling the creation of an emulsion.
An emulsion is a physicochemical form that is created by dispersing and mixing the water phase and the oil phase.
Examples of cosmetic emulsions are creams, milks and balms.

Propylene Glycol Isostearate acts as a rheology modifier (i.e. improves consistency by increasing viscosity) in washing preparations containing anionic surfactants.
This is possible by creating the so-called mixed micelles.
An opacifying agent that gives a cloudy or opalescent, pearly appearance to transparent cleaning products.



COSMETIC EFFECT OF PROPYLENE GLYCOL ISOSTEARATE:
*Emollient:
When used in skin and hair care preparations, Propylene Glycol Isostearate creates an occlusive layer (film) on their surface, which prevents excessive evaporation of water from the surface (this is an indirect moisturizing effect), thereby conditioning the skin and hair, softening and smoothing it.



SECURITY OF PROPYLENE GLYCOL ISOSTEARATE:
Propylene Glycol Isostearate is safe for use in cosmetics.
Cosmetic Ingredient Review: A CIR panel of experts assessed the safety of Propylene Glycol Isostearate.
Propylene Glycol Isostearate has no toxic effect, is not mutagenic, carcinogenic, reprotoxic or phototoxic.
Propylene Glycol Isostearate does not irritate the skin or have any sensitizing properties.



INFORMATION OF PROPYLENE GLYCOL ISOSTEARATE:
Ingredient on the basis of propylene glycol (1,2-propanediol).
"Glycol" refers to divalent alcohol as alcoholic component of this ingredient (ethylene glycol, propylene glycol, butylene glycol, pentylene glycol, hexylene glycol and others).
Isostearates are salts or esters of the isostearic acid (isooctadecanoic acid).



PHYSICAL and CHEMICAL PROPERTIES of PROPYLENE GLYCOL ISOSTEARATE:
CAS Number: 68171-38-0 / 63799-53-1
Chem/IUPAC Name: Isooctadecanoic acid, monoester with propane-1,2-diol
EINECS/ELINCS No: 269-027-5
CAS No.: 57-55-6
Molecular Formula: C3H8O2
Molecular Weight: 76.09
Property: Clear viscous liquid.
MDL: MFCD00152773
XlogP3-AA: 8.00 (est)
Molecular Weight: 342.56334000
Formula: C21 H42 O3
CAS Number: 63799-53-1

Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 443.00 to 444.00 °C. @ 760.00 mm Hg (est)
Flash Point: 328.00 °F. TCC ( 164.70 °C. ) (est)
logP (o/w): 7.826 (est)
Soluble in: water, 0.00717 mg/L @ 25 °C (est)
CAS Number: 63799-53-1
Name: propylene glycol isostearate
Molecular Formula: C21H42O3
Molecular Weight: 342.55638
Density: N/A
Boiling Point: N/A
Melting Point: N/A
Flash Point: N/A



FIRST AID MEASURES of PROPYLENE GLYCOL ISOSTEARATE:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of PROPYLENE GLYCOL ISOSTEARATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of PROPYLENE GLYCOL ISOSTEARATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of PROPYLENE GLYCOL ISOSTEARATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of PROPYLENE GLYCOL ISOSTEARATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of PROPYLENE GLYCOL ISOSTEARATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


PROPYLENE GLYCOL ISOSTEARATE
Propylene Glycol Isostearate is a white solid.
Propylene Glycol Isostearate has high oil content grease.
Propylene Glycol Isostearate is a synthetic compound composed of propylene glycol and stearic acid.


CAS Number: 68171-38-0 / 63799-53-1
EC Number: 269-027-5
MDL Number: MFCD00152773
Chem/IUPAC Name: Isooctadecanoic acid, monoester with propane-1,2-diol
Molecular Formula: C21H42O3



SYNONYMS:
1,2-Propandiol,Propylenglykol, ISOOCTADECANOIC ACID, MONOESTER WITH 1,2-PROPANEDIOL, MONOESTER WITH 1,2-PROPANEDIOL ISOOCTADECANOIC ACID, PROPYLENE GLYCOL ISOSTEARATE, and PROPYLENE GLYCOL MONOISOSTEARATE, CAS number: 68171-38-0 / 63799-53-1, Isooctadecanoic acid, monoester with propane-1,2-diol,



Propylene Glycol Isostearate is an ester of propylene glycol and isostearic acid.
Isostearic acid is a lightly chained liquid fatty acid obtained from natural sources like vegetable oils.
Propylene Glycol Isostearate is a white solid.


Propylene Glycol Isostearate has high oil content grease.
Propylene Glycol Isostearate is an ester of propylene glycol and isostearic acid.
Propylene Glycol Isostearate is a white to cream-colored soft waxy solid with a slightly fatty odor and taste.


Propylene Glycol Isostearate is an ester of propylene glycol and isostearic acid.
Isostearic acid is a lightly chained liquid fatty acid obtained from natural sources like vegetable oils.
Propylene Glycol Isostearate is a synthetic compound formed from propylene glycol and stearic acid.


Propylene Glycol Isostearate is a white to cream-colored soft waxy solid with a slightly fatty odor and taste.
Stearic acid is a naturally occurring fatty acid found in animal and vegetable oils.
Propylene Glycol Isostearate is an ester of propylene glycol and Isostearic Acid (q.v.).


Propylene Glycol Isostearate's HLB value is 3.
Propylene Glycol Isostearate is suitable for hot processes and is ideally added to the oil phase, the recommended usage range is 0.5 - 4.0%.
Propylene Glycol Isostearate is made from RSPO-certified, sustainable palm oil and has a Natural Origin Index (ISO 16128) of 0.83.


Propylene Glycol Isostearate is a mixture of propylene glycol and isostearic acid.
Propylene Glycol Isostearate can be used in co-emulsified series products and is very soft to the skin.
Propylene Glycol Isostearate can increase the brightness of lipstick and reduce sweating.


Use Propylene Glycol Isostearate with essential oils to enhance compatibility.
HLB=1~2, Propylene Glycol Isostearate is a w/o type co-emulsifier.
Propylene Glycol Isostearate is a synthetic compound composed of propylene glycol and stearic acid.


Propylene Glycol Isostearate is a soft, waxy, white to cream solid with a slightly oily odor and taste.
Stearic acid is a fatty acid found naturally in animal and vegetable oils.



USES and APPLICATIONS of PROPYLENE GLYCOL ISOSTEARATE:
Mixture of propylene glycol and stearic acid, Propylene Glycol Isostearate is used as a skin-conditioning agent and emulsifier.
Propylene Glycol Isostearate is used surfactant, thickener, skin conditioner, softening component, emulsive component, moistener.
As a surfactant, Propylene Glycol Isostearate carries both a water-loving group PG and a fat-loving group- isostearate.


The oil/ fat-loving group attracts dirt, impurities and attaches them to the surfactant molecule whereas because of the water-loving part Propylene Glycol Isostearate can be carried away with water and becomes cleaner.
With the same principle, Propylene Glycol Isostearate also acts as an emulsifier and prevents separation of the components, and enables even distribution of the product components when used.


Propylene Glycol Isostearate is used in formulations of creams, lotions, gels, shampoos, conditioners, sun care products, and other hair and skincare products.
In addition to its use in cosmetic products, Propylene Glycol Isostearate is also used in food processing like margarine.


Propylene Glycol Isostearate functions as a self-emulsifying agent in cosmetic products.
Propylene Glycol Isostearate is designed for use in face/neck care, body care, colour cosmetics and cleansers.
Propylene Glycol Isostearate comes in pellet form and has a melting point of 41°C.


Propylene Glycol Isostearate is used in cosmetic formulations.
Propylene Glycol Isostearate acts as an emollient (makes the skin smooth and supple).
Cosmetic Uses of Propylene Glycol Isostearate: skin conditioning and surfactants.


In addition to its use in cosmetic products, Propylene Glycol Isostearate is also used as margarine in the food industry.
Propylene Glycol Isostearate acts as a self-emulsifying agent in cosmetic products.
Propylene Glycol Isostearate is used as an emollient, humectant, emulsifier, and surfactant in cosmetic products.


As Propylene Glycol Isostearate is apparent both Propylene glycol and isostearic acid individually are very good in terms of skincare. PG can act as a humectant.
Propylene Glycol Isostearate draws water from water vapor present in the air and moisturizes the skin.


Propylene Glycol Isostearate can be used in all skin types, especially on normal and mild dry skin types.
Propylene Glycol Isostearate helps in retaining moisture in the skin. Isostearic acid is a fatty acid and it also acts as an emollient.
Propylene Glycol Isostearate fills up the gaps in between the top layer cells in the skin.


Propylene Glycol Isostearate makes skin appear smoother and tighter.
Propylene Glycol Isostearate forms a thin protective barrier on the surface of the skin and protects it from any allergen or bacteria which may compromise with skin’s health otherwise.



USE AND BENEFITS OF PROPYLENE GLYCOL ISOSTEARATE:
Propylene Glycol Isostearate is used as an emollient, humectant, emulsifier, and surfactant in cosmetic products.
As Propylene Glycol Isostearate is apparent both Propylene glycol and isostearic acid individually are very good in terms of skincare.
PG can act as a humectant.


Propylene Glycol Isostearate draws water from water vapor present in the air and moisturizes the skin.
Propylene Glycol Isostearate can be used in all skin types, especially on normal and mild dry skin types.
Propylene Glycol Isostearate helps in retaining moisture in the skin. Isostearic acid is a fatty acid and it also acts as an emollient.


Propylene Glycol Isostearate fills up the gaps in between the top layer cells in the skin.
Propylene Glycol Isostearate makes skin appear smoother and tighter.
Propylene Glycol Isostearate forms a thin protective barrier on the surface of the skin and protects it from any allergen or bacteria which may compromise with skin’s health otherwise.


As a surfactant, Propylene Glycol Isostearate carries both a water-loving group PG and a fat-loving group- isostearate.
The oil/ fat-loving group attracts dirt, impurities and attaches them to the surfactant molecule whereas because of the water-loving part Propylene Glycol Isostearate can be carried away with water and becomes cleaner.


With the same principle, it also acts as an emulsifier and prevents separation of the components, and enables even distribution of the product components when used.
Propylene Glycol Isostearate is used in formulations of creams, lotions, gels, shampoos, conditioners, sun care products, and other hair and skincare products.



OCCURRENCE OF PROPYLENE GLYCOL ISOSTEARATE:
Propylene Glycol Isostearate occurs creams, balms, milks, shower gels, soaps, shampoos, conditioners and hair masks,



HOW DOES PROPYLENE GLYCOL ISOSTEARATE WORK?
Propylene Glycol Isostearate creates a nourishing film on the surface of the skin and hair that prevents moisture from evaporating.
Propylene Glycol Isostearate has a softening, moisturizing and smoothing effect.
Propylene Glycol Isostearate enables the creation of an emulsion, combining the water phase with the oil phase.
Propylene Glycol Isostearate increases the viscosity of cosmetics, clouds too clear consistencies, and gives a pearly appearance to transparent preparations.



FROM THE SCIENTIFIC SIDE OF PROPYLENE GLYCOL ISOSTEARATE:
Propylene Glycol Isostearate is propylene glycol isostearate.
Propylene Glycol Isostearate is a lipophilic, non-ionic, surface-active substance.
Propylene Glycol Isostearate is insoluble in water.
Propylene Glycol Isostearate is completely safe for the skin, does not cause allergies or irritations.



FUNCTION OF PROPYLENE GLYCOL ISOSTEARATE:
Cleansing/Foaming ingredients - remove dirt and grease, can create foam
Propylene Glycol Isostearate is an emollient, surfactant, and emulsifier used in cosmetic and personal care products.



SAFETY OF PROPYLENE GLYCOL ISOSTEARATE:
There are currently no reports of harmful side effects of Propylene Glycol Isostearate on users' skin and health when used topically.



FUNCTIONS OF PROPYLENE GLYCOL ISOSTEARATE IN COSMETIC PRODUCTS:
*SKIN CONDITIONING:
Propylene Glycol Isostearate maintains the skin in good condition

*SURFACTANT - CLEANSING:
Surface-active agent to clean skin, hair and / or teeth

*Emulsifying :
Propylene Glycol Isostearate promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil)

*Opacifying :
Propylene Glycol Isostearate reduces transparency or translucency of cosmetics



WHAT DOES PROPYLENE GLYCOL ISOSTEARATE DO IN A FORMULATION?
*Skin conditioning
*Surfactant



WHAT IS PROPYLENE GLYCOL ISOSTEARATE USED FOR?
Here are its main functions:
*Attracts water:
Zeichner says at low concentrations, propylene glycol acts like a humectant, which means Propylene Glycol Isostearate binds water and pulls in hydration to the outer skin layer.
When used in cosmetic products, Propylene Glycol Isostearate helps give the skin a hydrated, dewy appearance.



FUNCTIONS OF PROPYLENE GLYCOL ISOSTEARATE:
*Skin care agent:
Propylene Glycol Isostearate maintains skin in good condition
*Surfactant:
Propylene Glycol Isostearate reduces the surface tension of cosmetics and contributes to the uniform distribution of the product during use



FUNCTIONAL GROUP OF PROPYLENE GLYCOL ISOSTEARATE:
*Base ingredients
*Active ingredients
*Preservatives
*UV filters
*Dyes
*Fragrances



FEATURES OF PROPYLENE GLYCOL ISOSTEARATE:
W/O emulsifier, an ingredient enabling the creation of an emulsion.
An emulsion is a physicochemical form that is created by dispersing and mixing the water phase and the oil phase.
Examples of cosmetic emulsions are creams, milks and balms.

Propylene Glycol Isostearate acts as a rheology modifier (i.e. improves consistency by increasing viscosity) in washing preparations containing anionic surfactants.
This is possible by creating the so-called mixed micelles.
An opacifying agent that gives a cloudy or opalescent, pearly appearance to transparent cleaning products.



COSMETIC EFFECT OF PROPYLENE GLYCOL ISOSTEARATE:
*Emollient:
When used in skin and hair care preparations, Propylene Glycol Isostearate creates an occlusive layer (film) on their surface, which prevents excessive evaporation of water from the surface (this is an indirect moisturizing effect), thereby conditioning the skin and hair, softening and smoothing it.



SECURITY OF PROPYLENE GLYCOL ISOSTEARATE:
Propylene Glycol Isostearate is safe for use in cosmetics.
Cosmetic Ingredient Review: A CIR panel of experts assessed the safety of Propylene Glycol Isostearate.
Propylene Glycol Isostearate has no toxic effect, is not mutagenic, carcinogenic, reprotoxic or phototoxic.
Propylene Glycol Isostearate does not irritate the skin or have any sensitizing properties.



INFORMATION OF PROPYLENE GLYCOL ISOSTEARATE:
Ingredient on the basis of propylene glycol (1,2-propanediol).
"Glycol" refers to divalent alcohol as alcoholic component of this ingredient (ethylene glycol, propylene glycol, butylene glycol, pentylene glycol, hexylene glycol and others).
Isostearates are salts or esters of the isostearic acid (isooctadecanoic acid).



PHYSICAL and CHEMICAL PROPERTIES of PROPYLENE GLYCOL ISOSTEARATE:
CAS Number: 68171-38-0 / 63799-53-1
Chem/IUPAC Name: Isooctadecanoic acid, monoester with propane-1,2-diol
EINECS/ELINCS No: 269-027-5
CAS No.: 57-55-6
Molecular Formula: C3H8O2
Molecular Weight: 76.09
Property: Clear viscous liquid.
MDL: MFCD00152773
XlogP3-AA: 8.00 (est)
Molecular Weight: 342.56334000
Formula: C21 H42 O3
CAS Number: 63799-53-1

Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 443.00 to 444.00 °C. @ 760.00 mm Hg (est)
Flash Point: 328.00 °F. TCC ( 164.70 °C. ) (est)
logP (o/w): 7.826 (est)
Soluble in: water, 0.00717 mg/L @ 25 °C (est)
CAS Number: 63799-53-1
Name: propylene glycol isostearate
Molecular Formula: C21H42O3
Molecular Weight: 342.55638
Density: N/A

Boiling Point: N/A
Melting Point: N/A
Flash Point: N/A
Alternate Name(s): Emerest 2389
Classification: Surfactant
CAS Number: 63799-53-1
Molecular Formula: C21H42O3
Molecular Weight: 342.55638
Density: N/A
Boiling Point: N/A
Melting Point: N/A



FIRST AID MEASURES of PROPYLENE GLYCOL ISOSTEARATE:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of PROPYLENE GLYCOL ISOSTEARATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of PROPYLENE GLYCOL ISOSTEARATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of PROPYLENE GLYCOL ISOSTEARATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of PROPYLENE GLYCOL ISOSTEARATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of PROPYLENE GLYCOL ISOSTEARATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


PROPYLENE GLYCOL METHYL ETHER
PROPYLENE GLYCOL METHYL ETHER = 1-METHOXY-2-PROPANOL = PGME


CAS Number: 107-98-2
EC Number: 203-539-1
MDL number: MFCD00004537
Linear Formula: CH3CH(OH)CH2OCH3 / C4H10O2


Propylene Glycol Methyl Ether (PGME or 1-methoxy-2-propanol) is an organic solvent with a wide variety of industrial and commercial uses.
Propylene Glycol Methyl Ether's Flash point is near 89 °F.
Propylene Glycol Methyl Ether is less dense than water.
Propylene Glycol Methyl Ether's vapors are heavier than air.


Propylene Glycol Methyl Ether is an organic solvent with a wide variety of industrial and commercial uses.
Propylene Glycol Methyl Ether (also known as propylene glycol monomethyl ether, PM, and PGME), is a colourless liquid that is soluble in water.
Propylene Glycol Methyl Ether is a methoxy alcohol derivative and has a formula of C4H10O2.
Propylene Glycol Methyl Ether is an organic compound that has no color, no odor, is a transparent viscous liquid and has a lightly sweet tatse.


Propylene Glycol Methyl Ether is a colorless liquid with a sweet ether-like odor and bitter taste.
Propylene Glycol Methyl Ether is soluble in water, ether, acetone, and benzene.
Propylene Glycol Methyl Ether (PGME), a glycol ether, can be synthesized by reacting propylene oxide with methanol in the presence of ZnMgAl (zinc-magnesium-aluminium) catalysts.


Propylene Glycol Methyl Ether is a glycol ether and a good biological indicator of exposure.
Propylene Glycol Methyl Ether is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 to < 1 000 000 tonnes per annum.
Propylene Glycol Methyl Ether, This hydrophilic solvent has 100% water solubility and is ideally suited as a coupling agent in a wide range of solvent systems.


Propylene Glycol Methyl Ether, 98% - is an organic solvent with a wide variety of industrial and commercial uses.
Propylene Glycol Methyl Ether is a color- less liquid.
Propylene Glycol Methyl Ether appears as a colorless liquid.
Propylene Glycol Methyl Ether's flash point is near 89°F.


Propylene Glycol Methyl Ether is less dense than water.
Propylene Glycol Methyl Ether's vapors is heavier than air.
Propylene Glycol Methyl Ether is ethereal odor.
The Odor Threshold of Propylene Glycol Methyl Ether is 10 ppm.


Propylene Glycol Methyl Ether is miscible and hygroscopic with water, acetone and chloroform.
Propylene Glycol Methyl Ether is the fastest evaporating solvent of the glycol ether family.
Propylene Glycol Methyl Ether, also known as propylene glycol methyl ether, is a clear, colourless liquid with a faint ether-like odour.
Propylene Glycol Methyl Ether is a clear, hygroscopic, medium-volatility liquid with a mild, alcoholic odor.


Propylene Glycol Methyl Ether has low surface tension as well as excellent solvency and coupling abilities.
Propylene Glycol Methyl Ether is miscible with water and many common organic solvents.
Propylene Glycol Methyl Ether has colorless, medium-volatility, water-miscible neutral liquid with a mild, alcoholic odour.
Propylene Glycol Methyl Ether is soluble in water and has moderate volatility.


Propylene Glycol Methyl Ether is a propylene oxide-based glycol ether which is fast evaporating and hydrophilic.
For instance, Propylene Glycol Methyl Ether may react with acids (or form esters), oxidizing agents (to form the corresponding ketones or carboxylic acids), alkali metals (to form alcoholates) or aldehydes (to form acetals).
Propylene Glycol Methyl Ether may form peroxides with atmospheric oxygen.


By virtue of it's ether and alcohol groups, Propylene Glycol Methyl Ether has very good solvent power for many of the raw materials used in coatings, e. g. resins, binders, etc.
Propylene Glycol Methyl Ether possesses the typical properties of the ether and alcohol groups.



USES and APPLICATIONS of PROPYLENE GLYCOL METHYL ETHER:
Propylene Glycol Methyl Ether is excellent solvent for nitrocellulose, alkyd resin and maleic anhydride modified phenolic resin
Propylene Glycol Methyl Ether is used as an antifreeze in diesel engines, a solvent and as an antifreeze agent, and a cleaning agent in the LCD and electronics industry.
Propylene Glycol Methyl Ether is primarily used as a chemical building block for the production of propylene glycol methyl ether acetate.


Propylene Glycol Methyl Ether is used in coatings, inks, printing and dyeing, pesticides, cellulose, acrylates, etc.
Propylene Glycol Methyl Ether appears as a colorless liquid.
Propylene Glycol Methyl Ether is used as a solvent and as an antifreeze agent.
Propylene Glycol Methyl Ether acts as a good biological indicator, and a reagent in the synthesis of metolachlor.


Propylene Glycol Methyl Ether is also used in cleaning products such as glass and rug cleaners, carbon and grease removers, and paint and varnish removers; and in pesticide formulations as a solvent for applications to crops and animals.
Propylene Glycol Methyl Ether is used as Solvent for agricultural pesticides, deactivator and emollient for livestock pesticides.
Propylene Glycol Methyl Ether is used as Component in the solvent phase for wood stains and polishes.


Propylene Glycol Methyl Ether is used as an additive for jet fuel antifreeze and brake fluid
Propylene Glycol Methyl Ether is used as a solvent, dispersant and diluent, also as a fuel antifreeze, extractant
Propylene Glycol Methyl Ether is used in the following products: coating products, washing & cleaning products, anti-freeze products and cosmetics and personal care products.


Propylene Glycol Methyl Ether is used as an Additive in cleaners, e. g. for metals, windows and floors.
Propylene Glycol Methyl Ether is also used in food and tabacco products as a humectant, preservative and solvent.
Propylene Glycol Methyl Ether is used as an active solvent for solvent-based coatings and tail solvent for solvent based gravure and flexographic printing inks.


Propylene Glycol Methyl Ether is used as Excellent solvent for nitrocellulose, alkyd resin and maleic anhydride modified phenolic resin
Propylene Glycol Methyl Ether is used Coupling agent and solvent for household and industrial cleaners, rust removers, and hard surface cleaners.
Propylene Glycol Methyl Ether possesses properties similar to those of methoxyethanol and ethoxyethanol and used in the same applications, particularly in coatings and printing inks.


Propylene Glycol Methyl Ether is widely used in coatings and cleaners.
Propylene Glycol Methyl Ether is also present in many everyday products such as polish, laundry aids, caulk, sealants, pesticides, inks for ballpoint and felt-tip pens, synthetic resin and rubber adhesives.
Propylene Glycol Methyl Ether is used as starting material in the production of Methoxypropyl Acetate, which is also an excellent solvent.


Propylene Glycol Methyl Ether is used as a solvent for cellulose, acrylics, dyes, inks, and cellophane.
Cosmetic Uses of Propylene Glycol Methyl Ether: perfuming agents and solvents
Other release to the environment of Propylene Glycol Methyl Ether is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.


Propylene Glycol Methyl Ether can be used as the active solvent of water-based coatings; Active solvent and coupling agent of solvent based printing ink; Solvent for ballpoint pens and pens; Coupling agents and solvents for household and industrial cleaners, derusting agents and hard surface cleaners; Solvents for agricultural pesticides; Mixed with propylene glycol n-butyl ether for glass cleaner formula.
Propylene Glycol Methyl Ether is used Carrier solvent for ball point and felt tip writing pen inks.


Propylene Glycol Methyl Ether is used as Starting material in the production of esters that may be used as plasticizers.
Propylene Glycol Methyl Ether is used as a reagent in the synthesis of 2-amino-3-carboxy-4-phenylthiophenes, which acts as a protein kinase C inhibitors.
Propylene Glycol Methyl Ether is formulated into a wide range of cleaners for industrial and commercial use such as those for ovens, glass, hard surfaces, floors, carpets and upholstery, as well as in speciality sanitation products such as swimming pool cleaners.


Propylene Glycol Methyl Ether, 99% Cas no 107-98-2 - is used as a reagent in the synthesis of 2-amino-3-carboxy-4-phenylthiophenes, which acts as a protein kinase C inhibitors.
Propylene Glycol Methyl Ether is used as a solvent, dispersant and diluent, also as a fuel antifreeze, extractant.
Propylene Glycol Methyl Ether is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Propylene Glycol Methyl Ether is used as solvent of nitrocellulose, compounding agent of brake oil and detergent, etc.
Propylene Glycol Methyl Ether is predominately used in the manufacture of propylene glycol methyl ether acetate (otherwise known as PMA) and is also used in industrial and commercial products including paints, varnishes, inks, synthetic resin and rubber adhesives, and automotive and oven cleaners.


Similar to other glycol ethers, Propylene Glycol Methyl Ether is used as a carrier/solvent in printing/writing inks and paints/coatings.
Propylene Glycol Methyl Ether is used as an additive for jet fuel antifreeze and brake fluid
Propylene Glycol Methyl Ether is used in coatings, inks, printing and dyeing, pesticides, cellulose, acrylates, etc.
Propylene Glycol Methyl Ether is used as Component in copying fluids (particularly together with alcohols, inks, and felt-tip pen inks), and Component in the solvent phase for road marking paints.


Propylene Glycol Methyl Ether is used as a solvent in manufacturing processes for the chemical, automotive and agricultural industries and in paint, lacquer and varnishes.
Propylene Glycol Methyl Ether is used as a coalescing agent in water-based paints and inks where it promotes polymer fusion during the drying process.


Propylene Glycol Methyl Ether is mainly used as solvent, dispersant and diluent, as well as fuel antifreeze, extractant, etc.
Propylene Glycol Methyl Ether is primarily used in the manufacture of lacquers and paints, as an anti-freeze in industrial engines, a tailing agent for inks used on very high-speed presses, a coupling agent for resins and dyes in waterbased inks, and a solvent for celluloses, acrylics, dyes, inks, and stains.


Propylene Glycol Methyl Ether is used Coupling agent in solvent blends for water-based gravure, flexographic, and silk screen printing inks.
Propylene Glycol Methyl Ether is used Solvent for cellulose, acrylics, dyes, inks, and stains; lacquers and paints, and Solvent or leather finishes and stamp pad inks
Nearly half of all propylene glycol made is used for the fabrication of unsaturated polyester resin.


Propylene Glycol Methyl Ether also finds use as an industrial and commercial paint stripper.
Propylene Glycol Methyl Ether has a high water solubility, excellent solvent with good coupling properties making it suitable for cleaning solutions and coating applications.
Propylene Glycol Methyl Ether acts as a good biological indicator.


Propylene Glycol Methyl Ether's favourable physiological properties make it preferable to methoxyethanol and ethoxyethanol as a solvent for coatings and printing inks.
Propylene Glycol Methyl Ether is also used as a reagent in the synthesis of metolachlor.
Further, Propylene Glycol Methyl Ether is used as a solvent and an antifreeze agent.


-Printing inks uses of Propylene Glycol Methyl Ether:
Propylene Glycol Methyl Ether is eminently suitable for use in printing inks, e.g. for cellulose nitrate flexographic inks.
Propylene Glycol Methyl Ether can also be used in gravure inks.
Propylene Glycol Methyl Ether regulates, i. e. retards, the drying of printing inks, but two facts should be noted in this respect.
Propylene Glycol Methyl Ether (evaporation rate= 22; ether = 1) dries more rapidly than ethoxyethanol (evaporation rate = 43).
In other words, somewhat greater amounts are required to retard drying.
A general rule is that drying regulators incur the risk of solvent retention and blocking if their proportion is too high or
if inadequate time is allowed for drying.
This also applies to Propylene Glycol Methyl Ether.
Propylene Glycol Methyl Ether can also be used for cleaning printing plates and for thinning printing inks.


-Coatings Industry uses of Propylene Glycol Methyl Ether:
The main application for Propylene Glycol Methyl Ether in the coatings industry is the production of cellulose nitrate lacquers.
The initial solutions can be thinned with many cheap diluents, yet still dry to give clear, transparent coatings of good strength.
Propylene Glycol Methyl Ether improves the brushability, levelling and gloss of air drying paints and prevents blushing.
Propylene Glycol Methyl Ether is included in formulations for paints applied by a spray-gun for the purpose of improving gloss and adhesion.
Similar to other glycol ethers, Propylene Glycol Methyl Ether is used as a carrier/solvent in printing/writing inks and paints/coatings.
Propylene Glycol Methyl Ether also finds use as an industrial and commercial paint stripper.
Propylene Glycol Methyl Ether is used as an antifreeze in diesel engines.


-Applications of Propylene Glycol Methyl Ether:
*Architectural coatings
*Auto OEM
*Auto refinish
*Automotive
*Building materials
*Commerical printing inks
*General industrial coatings
*Graphic arts
*Janitorial & household cleaners
*Marine
*Paints & coatings
*Protective coatings
*Wood coatings



KEY ATTRIBUTES OF PROPYLENE GLYCOL METHYL ETHER:
*Excellent solvent activity
*Good coupling efficiency
*High dilution ratio
*Inert - Food use with limitations
*Inert - Nonfood use
*Medium evaporation rate
*Miscible with water and most organic liquids
*Non-HAP
*Non-SARA
*Readily biodegradable
*Product description
*Propylene Glycol Monomethyl Ether, a medium-boiling glycol ether, is an active solvent for cellulose acetate butyrate, nitrocellulose, epoxy, phenolic, acrylic, and alkyd resins.
Propylene Glycol Methyl Ether is used in a variety of coating, printing ink, and cleaning applications.



HOW IS PROPYLENE GLYCOL METHYL ETHER PRODUCED?
Propylene Glycol Methyl Ether is produced by the reaction of 1,2-epoxy propane and methanol in the presence of a catalyst, and this is then followed by distillation.
The worldwide annual production of Propylene Glycol Methyl Ether is approximately 100,000 to 500,000 tonnes.



REACTIVITY PROFILE of PROPYLENE GLYCOL METHYL ETHER:
Propylene Glycol Methyl Ether is a methoxy alcohol derivative.
The ether being relatively unreactive.
They react with oxoacids and carboxylic acids to form esters plus water.
Oxidizing agents convert them to aldehydes or ketones.
Alcohols exhibit both weak acid and weak base behavior.
They may initiate the polymerization of isocyanates and epoxides.



PHYSICAL and CHEMICAL PROPERTIES of PROPYLENE GLYCOL METHYL ETHER:
Chemical formula: C4H10O2
Molar mass: 90.122 g·mol−1
Appearance: Colorless liquid
Odor: Ethereal
Density: 0.92 g/cm3 (20 °C)
Melting point: −97 °C (−143 °F; 176 K)
Boiling point: 120 °C (248 °F; 393 K)
Solubility in water: Miscible
log P: -0.45
Molecular Weight: 90.12
Appearance Form: liquid, clear
Color: colorless
Odor: ethanolic
Odor Threshold: No data available

pH: No data available
Melting point/freezing point:
Melting point: -96 °C at 1.013 hPa - (ECHA)
Initial boiling point and boiling range: 118 - 119 °C - lit.
Flash point: 34 °C - closed cup
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 16 %(V)
Lower explosion limit: 1,8 %(V)
Vapor pressure: 14,53 hPa at 25 °C
Vapor density: 3,11 - (Air = 1.0)
Density: 0,916 g/cm3 at 25 °C - lit.
Relative density: No data available
Water solubility: 1.000 g/l at 20 °C
Partition coefficient: n-octanol/water

Pow: < 1 at 20 °C - Bioaccumulation is not expected.
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 1,7 mPa.s at 25 °C
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Surface tension: 70,7 mN/m at 1g/l at 20 °C
Relative vapor density: 3,11 - (Air = 1.0)
Boiling point: 120 °C (1013 mbar)
Density: 0.921 g/cm3 (25 °C)
Explosion limit: 1.7 - 11.5 %(V)
Flash point: 34 °C
Ignition temperature: 287 °C

Melting Point: -96 °C
pH value: 4 - 7 (200 g/l, H₂O, 20 °C)
Vapor pressure: 11.33 hPa (20 °C)
Physical Form (at 20°C): Liquid
Boiling Point: 118-119°C(lit.)
Flash Point: 34°C
Refractive Index: 1.403
Long-Term Storage: Store long-term in a cool, dry place
Molecular Weight: 90.12
XLogP3-AA: -0.2
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 2
Exact Mass: 90.068079557
Monoisotopic Mass: 90.068079557
Topological Polar Surface Area: 29.5 Ų
Heavy Atom Count: 6

Formal Charge: 0
Complexity: 28.7
Appearance: colorless clear liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.92200 @ 25.00 °C.
Melting Point: 119.00 °C. @ 760.00 mm Hg
Boiling Point: 119.00 °C. @ 760.00 mm Hg
Vapor Pressure: 8.152000 mmHg @ 25.00 °C. (est)
Flash Point: 93.00 °F. TCC ( 33.89 °C. )
logP (o/w): -0.342 (est)
Soluble in:
alcohol
water, 1000000 mg/L @ 25 °C
water, 1e+006 mg/L @ 25 °C (est)



FIRST AID MEASURES of PROPYLENE GLYCOL METHYL ETHER:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of PROPYLENE GLYCOL METHYL ETHER:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Collect, bind, and pump off spills.
Take up with liquid-absorbent material.
Dispose of properly.



FIRE FIGHTING MEASURES of PROPYLENE GLYCOL METHYL ETHER:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of PROPYLENE GLYCOL METHYL ETHER:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use safety glasses.
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 120 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of PROPYLENE GLYCOL METHYL ETHER:
-Precautions for safe handling:
*Hygiene measures:
Change contaminated clothing.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of PROPYLENE GLYCOL METHYL ETHER:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available



SYNONYMS:
1-Methoxypropan-2-ol
PGME
1-Methoxy-2-propanol
Methoxypropanol
α-Propylene glycol monomethyl ether
1-Methoxy-2-propanol
1-Methoxypropan-2-ol
PGME
Methoxyisopropanol
Closol
Propylene glycol monomethyl ether
2-Propanol, 1-methoxy-
Dowtherm 209
Poly-Solve MPM
Propasol solvent M
Dowanol 33B
2-Methoxy-1-methylethanol
1-Methoxy-2-hydroxypropane
PROPYLENE GLYCOL METHYL ETHER
2-Propanol, methoxy-
Propylene glycol 1-methyl ether
NSC 2409
Dowanol-33B
1-methoxy-propan-2-ol
.alpha.-Propylene glycol monomethyl ether
Methyl proxitol
DSSTox_CID_4284
DSSTox_RID_77354
DSSTox_GSID_24284
UNII-74Z7JO8V3U
Ucar Solvent LM (Obs.)
HSDB 1016
UN3092
BRN 1731270
propyleneglycol monomethylether
AI3-15573
Glycol ether pm
Ucar solvent lm
Solvent PM
Gylcol Ether PM
Icinol PM
Poly-solv MPM
74Z7JO8V3U
Methoxy-2-propanol
3-methoxy-propan-2-ol
Propan-1-methoxy-2-ol
rac-1-methoxy-2-propanol
1,2-PROPYLENE GLYCOL 1-MONOMETHYL ETHER
2-methoxy-1-methyl ethanol
Propan-2-ol, 1-methoxy-
3-01-00-02146
propylene glycol monomethylether
1-Methoxy-2-propanol, 98%
Propyleneglycol monomethyl ether
Methoxypropanol, .alpha. isomer
CHEMBL3186306
DTXSID8024284
NSC2409
WLN: QY1 & 1O1
propylene glycol mono methyl ether
(+/-)2-methoxy-1-methylethanol
NSC-2409
Propylene Glycol 1-Monomethyl Ether
Tox21_201803
Tox21_303269
7109AF
1-Methoxy-2-propanol, >=99.5%
AKOS009158246
MCULE-7513310960
SB44649
SB44662
NCGC00249123-01
NCGC00256978-01
NCGC00259352-01
1-Methoxy-2-propanol, analytical standard
DB-016688
Propylene Glycol Methyl Ether Reagent Grade
FT-0608005
FT-0647598
FT-0654880
FT-0655258
M0126
E72455
Q1884806
1-Methoxy-2-propanol
Z1262237356
2-Propanol, 1-methoxy-
propylene glycol methyl ether
propylene glycol monomethyl ether
Propylene glycol methyl ether,Propyleneglycol monomethyl ether
PGME
Closol
Dowanol pm
MeCH(OH)CH2OMe
PGMME
1-methoxy-2-hydroxypropane
PM-EL
dowanol33b
2-methoxyisopropanol
Propylene Glycol 1-Monomethyl Ether
Solvent PM
Icinol PM
1-methoxy 2-propanol


PROPYLENE GLYCOL METHYL ETHER
DESCRIPTION:

Propylene glycol methyl ether is a clear, colorless liquid organic compound that belongs to the family of glycol ethers.
Propylene glycol methyl ether is also known by its chemical formula, CH₃OCH₂CH(CH₃)OH.
Propylene glycol methyl ether is a chemical compound commonly used in various industries.



CAS NUMBER: 107-98-2

EC NUMBER: 203-539-1

MOLECULAR FORMULA: CH₃OCH₂CH(OH)CH₃

MOLECULAR WEIGHT: 90.12 g/mol




DESCRIPTION:

Propylene glycol methyl ether is a clear, colorless liquid with a mild odor.
Propylene glycol methyl ether has a relatively low volatility and a high flash point, making it less flammable compared to some other solvents.
Propylene glycol methyl ether is still important to handle it with care and follow safety guidelines.
Propylene glycol methyl ether is classified as a slightly hazardous substance but is considered to have low acute toxicity.
Propylene glycol methyl ether can be irritating to the eyes and skin. Prolonged or repeated exposure may cause dermatitis or other health issues, so appropriate
protective measures should be taken.
Propylene glycol methyl ether is important to store PGME in a cool, well-ventilated area away from incompatible materials, open flames, or ignition sources.
Propylene glycol methyl ether is regulated in different countries and regions.
Propylene glycol methyl ether is important to comply with local regulations and guidelines when using or handling this chemical.

Propylene glycol methyl ether is considered to have low acute toxicity.
However, prolonged exposure to high concentrations may cause irritation to the eyes, skin, and respiratory system.
Propylene glycol methyl ether is important to handle it with proper care and follow safety guidelines.
Propylene glycol methyl ether's worth noting that while propylene glycol methyl ether is generally regarded as safe for its intended industrial uses.

Propylene glycol methyl ether is essential to follow proper safety precautions, including using appropriate personal protective equipment and following relevant guidelines and regulations.
Propylene glycol methyl ether is a medium-boiling glycol ether, is an active solvent for cellulose acetate butyrate, nitrocellulose, epoxy, phenolic, acrylic, and alkyd resins.
Propylene glycol methyl ether is used in a variety of coating, printing ink, and cleaning applications.

Propylene glycol methyl ether is primarily used in the chemical, agricultural (pesticides), automotive, paint and varnish industries.
Propylene glycol methyl ether is a mixture of two isomers (a and p) and contains less than 0.5% of the p-isomer.
The predominant use of Propylene glycol methyl ether is as a solvent in various manufacturing processes.
Propylene glycol methyl ether is the fastest evaporating solvent of the glycol ether family.

Propylene glycol methyl ether has a high water solubility, excellent solvent with good coupling properties making it suitable for cleaning solutions and coating applications.
This hydrophilic solvent has 100% water solubility and is ideally suited as a coupling agent in a wide range of solvent systems.
Propylene glycol methyl ether is a clear, colorless liquid with an ether-like odor.
Propylene glycol methyl ether is completely soluble in water, with moderate volatility and is used as a solvent.

Propylene glycol methyl ether is a clear, colourless liquid with a faint ether-like odour.
Propylene glycol methyl ether is soluble in water and has moderate volatility.
Propylene glycol methyl ether is a propylene oxide-based glycol ether which is fast evaporating and hydrophilic.
Propylene glycol methyl ether has low surface tension as well as excellent solvency and coupling abilities.
Propylene glycol methyl ether is produced by reacting propylene oxide with methanol using a catalyst.

Propylene glycol methyl ether is primarily used as a chemical building block for the production of propylene glycol methyl ether acetate.
Propylene glycol methyl ether is also used as a solvent in manufacturing processes for the chemical, automotive and agricultural industries and in paint, lacquer and varnishes.
Propylene glycol methyl ether is used as a coalescing agent in water-based paints and inks where it promotes polymer fusion during the drying process.
Propylene glycol methyl ether is formulated into a wide range of cleaners for industrial and commercial use such as those for ovens, glass, hard surfaces, floors, carpets and upholstery, as well as in speciality sanitation products such as swimming pool cleaners.

Propylene glycol methyl ether is also present in many everyday products such as polish, laundry aids, caulk, sealants, pesticides, inks for ballpoint and felt-tip pens, synthetic resin and rubber adhesives.
Propylene glycol methyl ether and its vapours are flammable.
Propylene glycol methyl ether should be stored in a cool, well-ventilated place away from sources of ignition.

Propylene glycol methyl ether must be isolated from incompatible materials such as strong oxidizers, bases and acids.
Propylene glycol methyl ether is a mild, but usually temporary, irritant to the eyes.
Repeated or prolonged contact with the skin may cause irritation, and in very large amounts skin absorption may cause drowsiness or dizziness.
High levels of methoxy propanol vapour may produce eye, nose and throat irritation, and at very high levels may produce anaesthetic or narcotic effects.
Unnecessary exposure should be prevented by appropriate work practices and engineering controls, adequate ventilation and by the use of approved personal protective equipment including gloves, clothing and safety goggles and the use of respirators where appropriate to the task being carried out.



USAGE AREAS:

-Architectural coatings
-Auto OEM
-Auto refinish
-Automotive
-Building materials
-Commerical printing inks
-General industrial coatings
-Graphic arts
-Janitorial & household cleaners
-Marine
-Paints & coatings
-Protective coatings
-Wood coatings



APPLICATION:

Propylene glycol methyl ether is primarily used as a solvent in various industries.
Propylene glycol methyl ether has excellent solvency power for a wide range of organic substances, including resins, coatings, paints, inks, dyes, and cleaning agents.
Propylene glycol methyl ether finds application as a coupling agent, viscosity modifier, and flow improver in industries such as electronics, textiles, printing, and manufacturing.
Propylene glycol methyl ether is used as an intermediate in the synthesis of various chemicals, including pharmaceuticals, agricultural chemicals, and fragrance compounds.
Propylene glycol methyl ether is often found in household and industrial cleaning products due to its solvency and low toxicity.



APPLICATION AREAS:

-Active solvent for solvent-based coatings.
-Active and tail solvent for solvent based gravure and flexographic printing inks.
-Coupling agent in solvent blends for water-based gravure, flexographic, and silk screen printing inks.
-Carrier solvent for ball point and felt tip writing pen inks.
-Coupling agent and solvent for household and industrial cleaners, rust removers, and hard surface cleaners.
-Solvent for agricultural pesticides, deactivator and emollient for livestock pesticides



USES:

Propylene glycol methyl ether is primarily used as a solvent in various applications, including paints, coatings, inks, dyes, and cleaning products.
Propylene glycol methyl ether helps dissolve or disperse other substances, improving the consistency and performance of these products.
Propylene glycol methyl ether finds applications in industrial processes such as metal cleaning, surface coatings, and chemical synthesis.

Propylene glycol methyl ether serves as an intermediate in the production of other chemicals, including resins, plasticizers, and pharmaceuticals.
Propylene glycol methyl ether can be found in some personal care products, such as cosmetics and skin care items, where it acts as a solvent or viscosity modifier.
Propylene glycol methyl ether is sometimes used as an excipient or a component in pharmaceutical formulations.



PHYSICAL AND CHEMICAL PROPERTIES:

-Molecular Formula: C₅H₁₂O₂
-Molecular Weight: 104.15 g/mol
-Density: 0.915 g/cm³
-Boiling Point: 122-124 °C (252-255 °F)
-Melting Point: -85 °C (-121 °F)
-Solubility: Miscible in water and most organic solvents
-Odor: Mild, ether-like odor



ATTRIBUTES:

-Excellent solvent activity
-Good coupling efficiency
-High dilution ratio
-Inert-Food use with limitations
-Inert-Nonfood use
-Medium evaporation rate
-Miscible with water and most organic liquids
-Non-HAP
-Non-SARA
-Readily biodegradable



SPECIFICATIONS:

-Chemical Formula: C4H10O2
-Molecular Weight: 90.12 g/mol
-CAS Number: 107-98-2
-Density: 0.92 g/cm³
-Boiling Point: 122-124 °C (252-255 °F)
-Melting Point: -85 °C (-121 °F)
-Solubility: Miscible in water and many organic solvents



STORAGE:

Store at +2°C to +25°C.



SYNONYM:

Propylene glycol monomethyl ether
Dowtherm 209
1-Methoxy-2-hydroxypropane
Propasol solvent M
Dowanol 33B
PROPYLENE GLYCOL METHYL ETHER
2-Methoxy-1-methylethanol
Methyl proxitol
2-Propanol, methoxy-
Propylene glycol 1-methyl ether
Propan-2-ol, 1-methoxy-
propylene glycol monomethylether
1-Methoxy-2-propanol, 98%
1-Methoxy-2-propanol (PGME)
Methoxypropanol, .alpha. isomer
(+/-)-1-methoxy-2-propanol
1 - methoxypropan - 2 - ol
CHEMBL3186306
METHOXYISOPROPANOL [INCI]
NSC2409
WLN: QY1 & 1O1
propylene glycol mono methyl ether
(+/-)2-methoxy-1-methylethanol
Propylene Glycol 1-Monomethyl Ether
Tox21_201803
Tox21_303269
LS-444
NA3092
1-Methoxy-2-propanol, >=99.5%
AKOS009158246
SB44649
SB44662
NCGC00249123-01
NCGC00256978-01
NCGC00259352-01
Propylene glycol monomethyl ether (PGME)
1-METHOXY-2-HYDROXYPROPANE [HSDB]
1-Methoxy-2-propanol, analytical standard
Propylene Glycol Methyl Ether Reagent Grade
FT-0608005
FT-0647598
FT-0654880
FT-0655258

PROPYLENE GLYCOL METHYL ETHER
Propylene glycol methyl ether is an organic solvent with a wide variety of industrial and commercial uses.
Similar to other glycol ethers, Propylene glycol methyl ether is used as a carrier/solvent in printing/writing inks and paints/coatings.
Propylene glycol methyl ether also finds use as an industrial and commercial paint stripper.

CAS: 107-98-2
MF: C4H10O2
MW: 90.12
EINECS: 203-539-1

Propylene glycol methyl ether is used as an antifreeze in diesel engines.
Propylene glycol methyl ether, a glycol ether, can be synthesized by reacting propylene oxide with methanol in the presence of ZnMgAl (zinc-magnesium-aluminium) catalysts.
Propylene glycol methyl ether's degradation by microorganisms in different soil types has been investigated.
Propylene glycol methyl ether is the fastest evaporating solvent of the glycol ether family.

Propylene glycol methyl ether has a high water solubility, excellent solvent with good coupling properties making it suitable for cleaning solutions and coating applications.
This hydrophilic solvent has 100% water solubility and is ideally suited as a coupling agent in a wide range of solvent systems.
Propylene glycol methyl ether appears as a colorless liquid. Flash point near 89 °F.
Less dense than water.
Contact irritates skin, eyes and mucous membranes.
Prolonged exposure to vapors may cause coughing, shortness of breath, dizziness and intoxication.

Vapors heavier than air.
Used as a solvent and as an antifreeze agent.
A colorless liquid.
Flash point near 89°F.
Less dense than water.
Contact irritates skin, eyes and mucous membranes.
Prolonged exposure to vapors may cause coughing, shortness of breath, dizziness and intoxication.
Vapors heavier than air.
Used as a solvent and as an antifreeze agent.

Propylene glycol methyl ether Chemical Properties
Melting point: -97 °C
Boiling point: 118-119 °C(lit.)
density: 0.922 g/mL at 25 °C(lit.)
vapor density: 3.12 (vs air)
vapor pressure: 10.9 mm Hg ( 25 °C)
refractive index: n20/D 1.403(lit.)
Fp: 93 °F
storage temp.: Store at +2°C to +25°C.
solubility water: miscible
form: Liquid
pka: 14.49±0.20(Predicted)
color: Colorless
PH: 4-7 (200g/l, H2O, 20℃)
Odor: sweet ether-like odor
explosive limit: 1.7-11.5%(V)
Water Solubility: soluble
Sensitive: Hygroscopic
BRN: 1731270
Exposure limits: TLV-TWA 100 ppm (370 mg/m3) (ACGIH); STEL 150 ppm (555 mg/m3) (ACGIH).
Stability: Stable. Highly flammable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides, water. Moisture-sensitive.
InChIKey: ARXJGSRGQADJSQ-UHFFFAOYSA-N
LogP: 0.37 at 20℃
CAS DataBase Reference: 107-98-2(CAS DataBase Reference)
NIST Chemistry Reference: Propylene glycol methyl ether (107-98-2)
EPA Substance Registry System: Propylene glycol methyl ether (107-98-2)

Propylene glycol methyl ether is a colorless liquid with a sweet ether-like odor and bitter taste.
Propylene glycol methyl ether is soluble in water, ether, acetone, and benzene.

Uses
Propylene glycol methyl ether is primarily used in the manufacture of lacquers and paints, as an anti-freeze in industrial engines, a tailing agent for inks used on very high-speed presses, a coupling agent for resins and dyes in waterbased inks, and a solvent for celluloses, acrylics, dyes, inks, and stains.
Propylene glycol methyl ether is also used in cleaning products such as glass and rug cleaners, carbon and grease removers, and paint and varnish removers; and in pesticide formulations as a solvent for applications to crops and animals.
Propylene glycol methyl ether is used as a solvent for cellulose, acrylics, dyes, inks, and cellophane.
Propylene glycol methyl ether acts as a good biological indicator.

Propylene glycol methyl ether is mainly used as solvent, dispersant and diluent, as well as fuel antifreeze, extractant, etc.
Used as solvent of nitrocellulose, compounding agent of brake oil and detergent, etc. Widely used in coatings and cleaners.
Propylene glycol methyl ether can be used as the active solvent of water-based coatings; Active solvent and coupling agent of solvent based printing ink; Solvent for ballpoint pens and pens; Coupling agents and solvents for household and industrial cleaners, derusting agents and hard surface cleaners; Solvents for agricultural pesticides; Mixed with propylene glycol n-butyl ether for glass cleaner formula.
A glycol ether and a good biological indicator of exposure.

Reactivity Profile
Propylene glycol methyl ether is a methoxy alcohol derivative.
The ether being relatively unreactive.
Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents.
They react with oxoacids and carboxylic acids to form esters plus water.
Oxidizing agents convert them to aldehydes or ketones.
Alcohols exhibit both weak acid and weak base behavior.
They may initiate the polymerization of isocyanates and epoxides.

Health Hazard
Propylene glycol methyl ether is a mild toxicant.
The toxicity is lower than that of the methyl, ethyl, and butyl ethers of ethylene glycol.
The toxic symptoms from inhaling high concentrations are nausea, vomiting, and general anesthetic effects.
In humans, toxic effects may be felt at exposure to a level of 3000–4000 ppm.
The oral and dermal toxicities in test animals were low.
The effects were mild depression of the central nervous system and a slight change in liver and kidney.

Synthesis
Propylene glycol methyl ether is used as a reagent in the synthesis of 2-amino-3-carboxy-4-phenylthiophenes, which acts as a protein kinase C inhibitors.
Propylene glycol methyl ether is also used as a reagent in the synthesis of metolachlor.

Synonyms
1-Methoxy-2-propanol
107-98-2
1-Methoxypropan-2-ol
Methoxyisopropanol
PGME
2-Propanol, 1-methoxy-
Closol
Propylene glycol monomethyl ether
Dowtherm 209
1-Methoxy-2-hydroxypropane
Propasol solvent M
Dowanol 33B
PROPYLENE GLYCOL METHYL ETHER
2-Methoxy-1-methylethanol
Methyl proxitol
2-Propanol, methoxy-
Propylene glycol 1-methyl ether
Ucar Solvent LM (Obs.)
NSC 2409
Dowanol-33B
HSDB 1016
1-methoxy-propan-2-ol
EINECS 203-539-1
UN3092
BRN 1731270
UNII-74Z7JO8V3U
.alpha.-Propylene glycol monomethyl ether
AI3-15573
74Z7JO8V3U
Propyleneglycol monomethyl ether
DTXSID8024284
NSC-2409
EC 203-539-1
3-01-00-02146 (Beilstein Handbook Reference)
DTXCID804284
CAS-107-98-2
propyleneglycol monomethylether
Glycol ether pm
Ucar solvent lm
Solvent PM
Icinol PM
methoxy isopropanol
Methoxy-2-propanol
MFCD00004537
1-methoxypropanol-2
1-Metoxipropan-2-ol
1-Metoksy-2-propanol
PME (CHRIS Code)
3-methoxy-propan-2-ol
Propan-1-methoxy-2-ol
2-Propanol, 1-metoxi-
rac-1-methoxy-2-propanol
1- methoxypropan- 2- ol
1,2-PROPYLENE GLYCOL 1-MONOMETHYL ETHER
2-methoxy-1-methyl ethanol
Propan-2-ol, 1-methoxy-
propylene glycol monomethylether
1-Methoxy-2-propanol, 98%
1-Methoxy-2-propanol (PGME)
Methoxypropanol, .alpha. isomer
(+/-)-1-methoxy-2-propanol
1 - methoxypropan - 2 - ol
CHEMBL3186306
METHOXYISOPROPANOL [INCI]
NSC2409
WLN: QY1 & 1O1
propylene glycol mono methyl ether
(+/-)2-methoxy-1-methylethanol
Propylene Glycol 1-Monomethyl Ether
Tox21_201803
Tox21_303269
LS-444
NA3092
1-Methoxy-2-propanol, >=99.5%
AKOS009158246
SB44649
SB44662
NCGC00249123-01
NCGC00256978-01
NCGC00259352-01
Propylene glycol monomethyl ether (PGME)
1-METHOXY-2-HYDROXYPROPANE [HSDB]
1-Methoxy-2-propanol, analytical standard
FT-0608005
FT-0647598
FT-0654880
FT-0655258
M0126
EN300-73396
E72455
PROPYLENE GLYCOL MONOMETHYL ETHER, ALPHA
1-Methoxy-2-propanol [UN3092] [Flammable liquid]
Q1884806
VOC Mixture 614 1.3-930 microg/mL in Triacetin
1-Methoxy-2-propanol [UN3092] [Flammable liquid]
VOC Mixture Kit 664 0.15-930 microg/mL in Triacetin
Z825742124
Propylene glycol monomethyl ether; (UCAR TRIOL HG-170)
Propylene glycol monomethyl ether; (UCAR TRIOL HG-170)
InChI=1/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H
PROPYLENE GLYCOL METHYL ETHER
Propylene Glycol Methyl Ether
CAS Number: 107-98-2



APPLICATIONS


Propylene Glycol Methyl Ether is used as a solvent in paints, inks, nail polish removers, and cleaning agents.
Also, Propylene Glycol Methyl Ether is used in finishing leather and in electronics and agriculture.

Propylene Glycol Methyl Ether is used to make lacquers and paints, as a solvent for resins, celluloses, acrylics, dyes, and inks (gravure, flexographic and silk screening), as antifreeze, and in household cleaners and spot removers.
Propylene Glycol Methyl Ether is chiefly used in manufacture of lacquers and paints.

Propylene Glycol Methyl Ether is a solvent for celluloses, acrylics, dyes, inks, stains.
Furthermore, Propylene Glycol Methyl Ether is solvent-sealing of cellophane.


Uses of Propylene Glycol Methyl Ether:

Architectural coatings
Auto OEM
Auto refinish
Automotive
Building materials
Commerical printing inks
General industrial coatings
Graphic arts
Janitorial & household cleaners
Marine
Paints & coatings
Protective coatings
Wood coatings
Arts and crafts supplies which can not be assigned to a more refined category
Glue sticks, glitter glues, fabric glues, craft glue, spray mounts, stencil sprays, and other adhesives used for primarily craft purposes
Writing utensils containing liquid or gel ink
Fluids used to cover inked or typed text on paper allowing for over laying of new text
Products used for cleaning or safety in an occupational or industrial setting (e.g. industrial cleaning supplies or laundry detergent, eye wash, spill kits)
Cleaning and household care products that can not be placed in a more refined category
Bathtub, tile, and toilet surface cleaners
Cleaning products for carpet or other flooring, which do not fit into a more refined category
Carpet-cleaning products that may be used directly (or require dilution), includes solutions that may be used by hand or in mechanical carpet cleaners
Products used to control microbial pests on hard surfaces or laundry
Products used to clean glass, mirrors, and windows
Products used to clean hard surfaces in the home, including kitchen specific hard surface cleaners
Heavy duty hard surface cleaning products that may require dilution prior to use (i.e., may be concentrated)
Products used to clean grills, ovens, or range cooktops
Upholstery fabric cleaning products that may be used directly (or require dilution), includes solutions that may be used by hand or in upholstery cleaning machines
Materials used for construction (e.g. flooring, tile, sinks, bathtubs, mirrors, wall materials/drywall, wall-to-wall carpets, insulation, playground surfaces); includes semi-permanent fixtures such as faucets and light fixtures
Ink for inkjet printers
General formulation products used for home maintenance, which do not fit into a more refined category
General purpose repair adhesives including all purpose glues, super glue, and epoxies; not including wood glues
Liquid or gels designed to seal cracks or fill cracks and depressions on hard surfaces
Products for removing grease and other hydrophobic materials from hard surfaces
Formulation products related to, or used on or for insulation, which do not fit into a more refined category
Paint or stain related products that do not fit into a more refined category
Home improvement paints, excluding or not specified as oil-, solvent-, or water-based paints
Products applied to hard surfaces to remove paints and finishes
Septic system treatment products
Products for coating and protecting household surfaces other than glass, stone, or grout
Flame retardants used for various purposes
Products for coloring eye lids
Clear or colored nail enamels, polishes, basecoats, topcoats, and other acrylic coatings
Products used to control fungi pests in the garden or home
Carpet and upholstery cleaners for pet stains
Auto body waxes and coatings, excluding combo wash/wax products
Power steering fluids, transmission fluids, brake fluids, fuel injector cleaners, gas treatments, or leak stoppers
Petroleum-based or synthetic engine lubricants


Propylene Glycol Methyl Ether has been used as an antifreeze material, principally in ebullient cooling systems and in some heavy-duty diesel engines.
As a solvent component in paints and printing inks, Propylene Glycol Methyl Ether improves the wetting of some pigments and colorants.


Propylene Glycol Methyl Ether has a good solvency for:

cellulose nitrate
cellulose ethers
chlorinated rubber
poly(vinyl acetate)
poly(vinyl butyral)
ketone and ketone-formaldehyde resins
shellac
colophony
phenol-, melamine-, and urea-formaldehyde resins
alkyd resins
polyacrylates
polymethacrylates
castor oil
linseed oil
some vinyl chloride copolymers.

Being a moderately volatile solvent, Propylene Glycol Methyl Ether improves paint penetration, flow properties, and the gloss of paint coats; it also prevents blushing and formation of fish eyes and blisters.
Addition of methoxypropanol does not delay the drying of paint systems.


Industry and Consumer uses of Propylene Glycol Methyl Ether:

Adhesives and sealant chemicals
Corrosion inhibitor
Diluent
Dispersing agent
Functional fluids (closed systems)
Intermediates
Paint additives and coating additives not described by other categories
Photosensitive agent
Pigments
Sealant (barrier)
Solvents (for cleaning or degreasing)
Solvents (which become part of product formulation or mixture)
UV stabilizer
Viscosity adjustors
Cleaning agent
Corrosion inhibitor
Coating additives
Processing aids, specific to petroleum production
UV stabilizer
Viscosity adjustors


Propylene Glycol Methyl Ether is predominately used in the manufacture of propylene glycol methyl ether acetate (otherwise known as PMA) and is also used in industrial and commercial products including paints, varnishes, inks, synthetic resin and rubber adhesives, and automotive and oven cleaners.
Moreover, Propylene Glycol Methyl Ether is also used as a cleaning agent in the LCD and electronics industry.

Propylene Glycol Methyl Ether is a clear, colorless liquid with an ether-like odor and low toxicity.
Besides, Propylene Glycol Methyl Ether is an organic solvent that is a fast evaporator.

Propylene Glycol Methyl Ether is water soluble and miscible with a number of other organic solvents

In addition, Propylene Glycol Methyl Ether is used as a solvent for a variety of industrial and consumer applications: for paints, varnishes, celluloses, acrylics, dyes, inks, stains, etc.
Propylene Glycol Methyl Ether may be used as an industrial paint stripper, or as antifreeze in diesel engines.

Additionally, Propylene Glycol Methyl Ether is used as a chemical intermediate, in cleaners and degreasers, in coatings, and in the manufacture of electronics.
Propylene Glycol Methyl Ether may be used in agricultural, cosmetic, and adhesives products.


Features of Propylene Glycol Methyl Ether:

Excellent solvent activity
Good coupling efficiency
High dilution ratio
Inert - Food use with limitations
Inert - Nonfood use
Medium evaporation rate
Miscible with water and most organic liquids
Non-HAP
Non-SARA
Readily biodegradable


Propylene Glycol Methyl Ether is primarily used as a chemical building block for the production of propylene glycol methyl ether acetate.
More to that, Propylene Glycol Methyl Ether is also used as a solvent in manufacturing processes for the chemical, automotive and agricultural industries and in paint, lacquer and varnishes.
Propylene Glycol Methyl Ether is used as a coalescing agent in water-based paints and inks where it promotes polymer fusion during the drying process.

Propylene Glycol Methyl Ether is formulated into a wide range of cleaners for industrial and commercial use such as those for ovens, glass, hard surfaces, floors, carpets and upholstery, as well as in speciality sanitation products such as swimming pool cleaners.
Further to that, Propylene Glycol Methyl Ether is also present in many everyday products such as polish, laundry aids, caulk, sealants, pesticides, inks for ballpoint and felt-tip pens, synthetic resin and rubber adhesives.



DESCRIPTION


Propylene Glycol Methyl Ether mixture of isomers is a monohydric alcohol that is used as an additive in cosmetics and pharmaceutical products.
Besides, Propylene Glycol Methyl Ether has good solvency for water-insoluble substances such as silicone oils, n-butyl alcohol, and methyl alcohol.

Propylene Glycol Methyl Ether, mixture of isomers can also be used as a solvent for in vitro tests.
With its low viscosity and high boiling point (at atmospheric pressure), Propylene Glycol Methyl Ether can be used at temperatures between -20 °C to 120 °C.

Propylene Glycol Methyl Ether is an organic solvent with a wide variety of industrial and commercial uses.
Similar to other glycol ethers, Propylene Glycol Methyl Ether is used as a carrier/solvent in printing/writing inks and paints/coatings. It also finds use as an industrial and commercial paint stripper.
Propylene Glycol Methyl Ether is used as an antifreeze in diesel engines.

Propylene Glycol Methyl Ether, a medium-boiling glycol ether, is an active solvent for cellulose acetate butyrate, nitrocellulose, epoxy, phenolic, acrylic, and alkyd resins.
Furthermore, Propylene Glycol Methyl Ether is used in a variety of coating, printing ink, and cleaning applications.

The chemical substances for Propylene Glycol Methyl Ether are listed as Inert Ingredients Permitted for Use in Nonfood Use Pesticide Products, and in Food Use Pesticide Products with limitations, under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA).

Propylene Glycol Methyl Ether appears as a colorless liquid.
Flash point of Propylene Glycol Methyl Ether is near 89 °F.

Propylene Glycol Methyl Ether is less dense than water.
Contact irritates skin, eyes and mucous membranes.

Prolonged exposure to vapors of Propylene Glycol Methyl Ether may cause coughing, shortness of breath, dizziness and intoxication.
Vapors of Propylene Glycol Methyl Ether are heavier than air.
Propylene Glycol Methyl Ether is used as a solvent and as an antifreeze agent.

Propylene Glycol Methyl Ether is a clear, colourless liquid with a faint ether-like odour.
Moreover, Propylene Glycol Methyl Ether is soluble in water and has moderate volatility.

Propylene Glycol Methyl Ether is a propylene oxide-based glycol ether which is fast evaporating and hydrophilic.
Besides, Propylene Glycol Methyl Ether has low surface tension as well as excellent solvency and coupling abilities.



PROPERTIES


Density: 0.9500g/mL
Melting Point: -80.0°C
Boiling Point: 180.0°C
Flash Point: 75°C
Assay Percent Range: 98.5% min. sum of isomers (GC)
Linear Formula: CH3O(CH2)3O(CH2)3OH
Packaging: Plastic drum
Solubility Information:
Solubility in water: soluble.
Other solubilities: miscible with benzene
Specific Gravity: 0.95
Formula Weight: 148.2
Percent Purity: 99%
Grade: Pure
Viscosity: 4 mPa.s (25°C)
Chemical Name or Material: Propylene Glycol Methyl Ether, Mixture of isomers
Chemical formula: C4H10O2
Molar mass: 90.122 g·mol−1
Appearance: Colorless liquid
Odor : Ethereal
Density: 0.92 g/cm3 (20 °C)
Melting point: −97 °C (−143 °F; 176 K)
Boiling point: 120 °C (248 °F; 393 K)
Solubility in water: Miscible
log P: 0.45
Molecular Weight: 90.12
XLogP3-AA: -0.2
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 2
Exact Mass: 90.068079557
Monoisotopic Mass: 90.068079557
Topological Polar Surface Area: 29.5 Ų
Heavy Atom Count: 6
Formal Charge: 0
Complexity: 28.7
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized : Yes



FIRST AID


General notes:

Do not leave affected person unattended.
Remove victim out of the danger area.
Keep affected person warm, still and covered.

Take off immediately all contaminated clothing.
In all cases of doubt, or when symptoms persist, seek medical advice.

In case of unconsciousness place person in the recovery position.
Never give anything by mouth.


Following inhalation:

If breathing is irregular or stopped, immediately seek medical assistance and start first aid actions.
Provide fresh air.


Following skin contact:

Wash with plenty of soap and water.


Following eye contact:

Remove contact lenses, if present and easy to do.
Continue rinsing.
Irrigate copiously with clean, fresh water for at least 10 minutes, holding the eyelids apart.


Following ingestion:

Rinse mouth with water (only if the person is conscious).
Do NOT induce vomiting.



HANDLING AND STORAGE


Propylene Glycol Methyl Ether and its vapours are flammable.
In addition, Propylene Glycol Methyl Ether should be stored in a cool, well-ventilated place away from sources of ignition.

Propylene Glycol Methyl Ether must be isolated from incompatible materials such as strong oxidizers, bases and acids.
Additionally, Propylene Glycol Methyl Ether is a mild, but usually temporary, irritant to the eyes.

Repeated or prolonged contact with the skin may cause irritation, and in very large amounts skin absorption may cause drowsiness or dizziness.
High levels of Propylene Glycol Methyl Ether vapour may produce eye, nose and throat irritation, and at very high levels may produce anaesthetic or narcotic effects.

Unnecessary exposure should be prevented by appropriate work practices and engineering controls, adequate ventilation and by the use of approved personal protective equipment including gloves, clothing and safety goggles and the use of respirators where appropriate to the task being carried out.



SYNONYMS


1-Methoxy-2-propanol
107-98-2
1-Methoxypropan-2-ol
Methoxyisopropanol
PGME
2-Propanol, 1-methoxy-
Propylene glycol monomethyl ether
Closol
Dowtherm 209
1-Methoxy-2-hydroxypropane
Poly-Solve MPM
Propasol solvent M
Dowanol 33B
PROPYLENE GLYCOL METHYL ETHER
2-Methoxy-1-methylethanol
2-Propanol, methoxy-
Propylene glycol 1-methyl ether
NSC 2409
Dowanol-33B
1-methoxy-propan-2-ol
.alpha.-Propylene glycol monomethyl ether
74Z7JO8V3U
Propyleneglycol monomethyl ether
NSC-2409
Methyl proxitol
DSSTox_CID_4284
DSSTox_RID_77354
DSSTox_GSID_24284
Ucar Solvent LM (Obs.)
CAS-107-98-2
HSDB 1016
EINECS 203-539-1
UN3092
BRN 1731270
UNII-74Z7JO8V3U
propyleneglycol monomethylether
AI3-15573
Glycol ether pm
Ucar solvent lm
Solvent PM
Gylcol Ether PM
Icinol PM
methoxy isopropanol
Poly-solv MPM
Methoxy-2-propanol
MFCD00004537
3-methoxy-propan-2-ol
Propan-1-methoxy-2-ol
rac-1-methoxy-2-propanol
EC 203-539-1
1,2-PROPYLENE GLYCOL 1-MONOMETHYL ETHER
2-methoxy-1-methyl ethanol
Propan-2-ol, 1-methoxy-
3-01-00-02146 (Beilstein Handbook Reference)
propylene glycol monomthylether
1-Methoxy-2-propanol, 98%
Methoxypropanol, .alpha. isomer
(+/-)-1-methoxy-2-propanol
CHEMBL3186306
DTXSID8024284
METHOXYISOPROPANOL [INCI]
NSC2409
WLN: QY1 & 1O1
propylene glycol mono methyl ether
(+/-)2-methoxy-1-methylethanol
Propylene Glycol 1-Monomethyl Ether
Tox21_201803
Tox21_303269
1-Methoxy-2-propanol, >=99.5%
AKOS009158246
SB44649
SB44662
NCGC00249123-01
NCGC00256978-01
NCGC00259352-01
1-METHOXY-2-HYDROXYPROPANE [HSDB]
1-Methoxy-2-propanol, analytical standard
DB-016688
Propylene Glycol Methyl Ether Reagent Grade
FT-0608005
FT-0647598
FT-0654880
FT-0655258
M0126
EN300-73396
E72455
Q1884806
1-Methoxy-2-propanol [UN3092] [Flammable liquid]
Z825742124
Propylene Glycol Methyl Ether Acetate
cas no 108-65-6 1,2-Propanediol monomethyl ether acetate; 1-Methoxy-2-propyl acetate; DOWANOL® PMA; MPA; PGMEA; Propylene glycol methyl ether acetate;
PROPYLENE GLYCOL METHYL ETHER ACETATE
Propylene Glycol Methyl Ether Acetate
Molecular Formula: C6H12O3 or CH3CH(OCOCH3)CH2OCH3
CAS Number
108-65-6



APPLICATIONS


Propylene Glycol Methyl Ether Acetate is a clear, colorless liquid ester.
Furthermore, Propylene Glycol Methyl Ether Acetate is used in an industrial setting as a solvent for automotive paints and industrial coatings, as a solvent in the electronics industry and in silk screen inks.

Propylene Glycol Methyl Ether Acetate is found in household cleaners, paints, spray paints, lacquers, varnishes and pesticides.
Moreover, Propylene Glycol Methyl Ether Acetate is very efficient at dissolving resins used in paints, inks, lacquers, and other types of surface coatings.

Propylene Glycol Methyl Ether Acetate has been used in the development of fluidic channels to be incorporated in a poly(dimethylsiloxane) (PDMS)-based microfluidic device.


Uses of Propylene Glycol Methyl Ether Acetate:

Aerospace coatings
Architectural coatings
Auto OEM
Auto plastics
Auto refinish
Automotive parts & accessories
Commerical printing inks
Furniture
General industrial coatings
Industrial cleaners
Industrial maintenance
Janitorial & household cleaners
Marine
Molding & trim interior
Packaging inks non food contact
Process solvents
Protective coatings
Road markings
Solvents/stripping agents
Truck/bus/RV
Wood coatings


Propylene Glycol Methyl Ether Acetate (PGMEA, 1-methoxy-2-propanol acetate) is a P-type glycol ether used in inks, coatings, and cleaners. Besides, Besides, Propylene Glycol Methyl Ether Acetate is sold by different companies under different titles.

In the semiconductor industry, Propylene Glycol Methyl Ether Acetate is a commonly used solvent, primarily for the application of surface adherents such as Bis(trimethylsilyl)amine (HMDS) on silicon wafers.
Propylene Glycol Methyl Ether Acetate is often the most abundant airborne, molecular contamination (AMC) in semiconductor cleanrooms, due to its evaporation into ambient air.

Propylene Glycol Methyl Ether Acetate has been used in the development of fluidic channels to be incorporated in a poly(dimethylsiloxane) (PDMS)-based microfluidic device.

Propylene Glycol Methyl Ether Acetate is extensively used in many decorative and protective coating formulations.
In addition, Propylene Glycol Methyl Ether Acetate has a similar evaporation rate and solvency compared to EEA in an acrylic-epoxy baking enamel formulation.
Propylene Glycol Methyl Ether Acetate is also found to give better gloss and image distinction.

Propylene Glycol Methyl Ether Acetate is generally recommended over its acetates because acetates are subject to hydrolysis in very alkaline water-based cleaners.
However, for solvent-based cleaning, including metal degreasing and specialized equipment cleansing Propylene Glycol Methyl Ether Acetate alone and in conjunction with other solvents is being evaluated as a replacement for many chlorinated solvents.

The direction of current regulations is to eliminate the use of many chlorinated solvents in this application.
Propylene Glycol Methyl Ether Acetate has replaced EEA in photoresist formulations used in semiconductor processing.

In these processes, Propylene Glycol Methyl Ether Acetate is used in the positive photoresist formulation.
Propylene Glycol Methyl Ether Acetate may also be used in solvent systems for cleaning and degreasing circuit boards and removing solder flux.

Propylene Glycol Methyl Ether Acetate shows very broad solvency.
Solvency characteristics of Propylene Glycol Methyl Ether Acetate generally match those of chlorinated solvents more closely than do glycol ethers and alcohols.


Some uses OF Propylene Glycol Methyl Ether Acetate:

Writing utensils containing liquid or gel ink
Cleaning products for carpet or other flooring, which do not fit into a more refined category
Materials used for construction (e.g. flooring, tile, sinks, bathtubs, mirrors, wall materials/drywall, wall-to-wall carpets, insulation, playground surfaces); includes semi-permanent fixtures such as faucets and light fixtures
Ink for inkjet printers
Toners used in laser printers
Items used to furnish a home or workplace, e.g. tables, chairs, sofa, outdoor patio furniture, sofa cover, hammock, mattress, area rug
General formulation products used for home maintenance, which do not fit into a more refined category
Adhesive and adhesive remover related products which do not fit into a more refined category
General purpose repair adhesives including all purpose glues, super glue, and epoxies; not including wood glues
Liquid or gels designed to seal cracks or fill cracks and depressions on hard surfaces
Products for removing grease and other hydrophobic materials from hard surfaces
Paint or stain related products that do not fit into a more refined category
Home improvement paints, excluding or not specified as oil-, solvent-, or water-based paints
Products used on wooden surfaces, including decks, to impart transparent or semitransparent color
Products for coating and protecting household surfaces other than glass, stone, or grout
Flame retardants used for various purposes
Body cleaners, washes, shower gels
Eye liners or brow coloring products
Colored lip products, excluding glosses
Care products specifically for cats which do not fit into a more refined category
Products used in or on vehicles, which do not fit into a more refined category
Paints and primers for auto body or engine
Products for masking odors or adding fragrance to car cabin air
Treatments for the surfaces/body of vehicles that can not be otherwise categorized

Propylene Glycol Methyl Ether Acetate has been used in the development of fluidic channels to be incorporated in a poly(dimethylsiloxane) (PDMS)-based microfluidic device.

Propylene Glycol Methyl Ether Acetate is a photoresist solvent.
Its degradation by microorganisms in different soil types has been investigated.
An oral reference dose (RfD) value of Propylene Glycol Methyl Ether Acetate has been obtained from inhalation studies.
The solubility of (5-alkylsulfonyloxyimino-5H-thiophen-2-ylidene)-2-methylphenyl-acetonitriles in Propylene Glycol Methyl Ether Acetate has been analyzed.

Propylene Glycol Methyl Ether Acetate is a colorless liquid with sweet Ether-like odor.
Additionally, Propylene Glycol Methyl Ether Acetate is used in cleaning solutions and as a solvent for coatings, acrylics, dyes, inks and stains.

ODOR THRESHOLD = 10 ppm
Odor thresholds of Propylene Glycol Methyl Ether Acetate vary greatly.
Do not rely on odor alone to determine potentially hazardous exposures.


Propylene Glycol Methyl Ether Acetate is used as a solvent for paints, inks, lacquers, varnishes, cleaners, coatings, ink-removers, and pesticides.
More to that, Propylene Glycol Methyl Ether Acetate is used in photoresist formulations in the semiconductor industry.

Also, Propylene Glycol Methyl Ether Acetate is used in solvents for degreasing circuit boards and in food contact applications.
Propylene Glycol Methyl Ether Acetate functions as a solvent in cosmetic formulations.
Further to that, Propylene Glycol Methyl Ether Acetate is used in surface coatings, inks, and cleaners.

Propylene Glycol Methyl Ether Acetate is used as a solvent for paints, inks, lacquers, varnishes, cleaners and coatings.

Propylene Glycol Methyl Ether Acetateis also used as a solvent for degreasing circuit boards and in food contact applications.
Further, Propylene Glycol Methyl Ether Acetate is used in photoresist formulations in the semiconductor industry.

Propylene Glycol Methyl Ether Acetate is a high-grade industrial solvent with low toxicity and excellent performance.
Furthermore, Propylene Glycol Methyl Ether Acetate has strong solubility for polar and non-polar substances.

Propylene Glycol Methyl Ether Acetate is suitable for solvents of various polymers of high-grade coatings and inks, including aminomethyl ester, vinyl, polyester, cellulose acetate, alkyd resin, acrylic resin, epoxy resin and nitrocellulose.
Among them. Propylene Glycol Methyl Ether Acetate is the best solvent in coatings and inks.
Propylene Glycol Methyl Ether Acetate is suitable for unsaturated polyester, polyurethane resin, acrylic resin, epoxy resin, etc.

Propylene Glycol Methyl Ether Acetate is a photoresist solvent.
Its degradation by microorganisms in different soil types has been investigated.

An oral reference dose (RfD) value of Propylene Glycol Methyl Ether Acetate has been obtained from inhalation studies.
The solubility of (5-alkylsulfonyloxyimino-5H-thiophen-2-ylidene)-2-methylphenyl-acetonitriles in Propylene Glycol Methyl Ether Acetate has been analyzed.


Industry and Consumer Uses of Propylene Glycol Methyl Ether Acetate:

Adhesion/cohesion promoter
Adhesives and sealant chemicals
Cleaning agent
Defoamer
Diluent
Dispersing agent
Finishing agents
Intermediates
Paint additives and coating additives not described by other categories
Photosensitive agent
Photosensitive chemicals
Pigments
Plating agents and surface treating agents
Solvents (for cleaning or degreasing)
Solvents (which become part of product formulation or mixture)
UV stabilizer
Wetting agent (non-aqueous)
Defoamer
Paint additives and coating additives not described by other categories
Photosensitive agent
Pigments
Sealant (barrier)


Methoxy propyl acetate, also known as Propylene Glycol Methyl Ether Acetate, is a clear, colourless liquid with a mild ether-like odour.
Propylene Glycol Methyl Ether Acetate is only slightly soluble in water but miscible with most common organic solvents.

Propylene Glycol Methyl Ether Acetate is slightly hygroscopic, relatively fast evaporating and has a low viscosity.
Moreover, Propylene Glycol Methyl Ether Acetate enters into reactions which are characteristic of both esters and ethers, displaying their good solvent power.

Propylene Glycol Methyl Ether Acetate is produced by reacting propylene oxide with methanol using a catalyst.

The main applications of Propylene Glycol Methyl Ether Acetate are in coatings and printing inks, where it is frequently used as an alternative to ethoxyethyl acetate.
Propylene Glycol Methyl Ether Acetate is used as a carrier solvent for resins and inks that are incompatible with water such as acrylics, epoxies, alkyds and polyesters.

Propylene Glycol Methyl Ether Acetate is formulated into a great many other industrial and commercial products such as paints, lacquers, varnishes, cleaners, ink removers, pesticides, adhesives, dyes for furniture polishes, wood stains, leather and textiles, and also as a binder for core sands in foundries.



DESCRIPTION


Propylene Glycol Methyl Ether Acetate is a colorless liquid with a sweet ether-like odor.
Besides, Propylene Glycol Methyl Ether Acetate is a clear liquid that has limited miscibility with water.

Propylene Glycol Methyl Ether Acetate is a medium volatility solvent with a mild odour and has the formula C6H12O3.
In addition, Propylene Glycol Methyl Ether Acetate is a photoresist solvent.

Propylene Glycol Methyl Ether Acetate is a slow evaporating solvent with both ether and ester functional groups.
Additionally, Propylene Glycol Methyl Ether Acetate is a colorless liquid with a mild odor.

Propylene Glycol Methyl Ether Acetate is an excellent solvent for many commonly used coating polymers, including cellulose acetate butyrate, nitrocellulose, epoxy resins, acrylic copolymers, and phenoxy resins.

The combination of slow evaporation rate and good solvent activity makes Propylene Glycol Methyl Ether Acetate acetate an effective retarder solvent for use in lacquers, thinners, and baking enamels.
Propylene Glycol Methyl Ether Acetate is supplied as a urethane grade solvent.

Propylene Glycol Methyl Ether Acetate is a glycol type solvent used in inks, coatings, and cleaners.
Ungraded products involving Propylene Glycol Methyl Ether Acetate are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.

Propylene Glycol Methyl Ether Acetate, also known as propylene glycol methyl ether acetate, is a colorless hygroscopic liquid with a unique odor.
More to that, Propylene Glycol Methyl Ether Acetate is a non-polluting solvent with multi-functional groups.
The molecular formula of Propylene Glycol Methyl Ether Acetate is C6H12O3.

Not only Propylene Glycol Methyl Ether Acetate is used as a solvent for printing ink, paint, ink, textile dyes and textile oil, it is also used as a cleaning agent in the production of liquid crystal displays.
Propylene Glycol Methyl Ether Acetate is flammable, and when the temperature is above 42°C, it may form explosive vapor/air mixture.


Features of Propylene Glycol Methyl Ether Acetate:

Excellent solvent activity
Non-HAP
Non-SARA
Readily biodegradable
Slow evaporation rate
Urethane grade

Propylene Glycol Methyl Ether Acetate is a colorless,combustible liquid with low toxicity.
Further to that, Propylene Glycol Methyl Ether Acetate has a characteristic ester odor and is soluble in water tothe extent of 18% at 20°C.

Propylene Glycol Methyl Ether Acetate has excellent solvency for a variety of substances including acrylic, nitrocellulose and urethane coating resins.
Furthermore, Propylene Glycol Methyl Ether Acetate is a substitute for certain ethyleneglycol (E-series) ether acetates, particularly EEA and EMA.

Propylene Glycol Methyl Ether Acetate, also known as propylene glycol monomethyl ether acetate, with molecular formula of C6H12O3, is a colorless hygroscopic liquid with special smell.
Moreover, Propylene Glycol Methyl Ether Acetate is a non pollution solvent with multi-functional groups.

Propylene Glycol Methyl Ether Acetate is mainly used as the solvent of ink, paint, ink, textile dye and textile oil agent, and also as the cleaning agent in the production of LCD.
Besides, Propylene Glycol Methyl Ether Acetate is flammable, may form explosive vapor / air mixture above 42 ° C.

Propylene glycol methyl ether acetate (PGMEA) is an advanced solvent.
Its molecule has both ether bond and carbonyl.

Propylene Glycol Methyl Ether Acetate forms the structure of ester and contains alkyl at the same time.
In the same molecule, there are both non-polar and polar parts.
The functional groups of these two parts not only restrict and repel each other, but also play their inherent roles.

Therefore, Propylene Glycol Methyl Ether Acetate has a certain solubility for non-polar substances and polar substances.
Propylene Glycol Methyl Ether Acetate is a material contains polar groups and non polar group , has good ability of dissolving and coupling, commonly used in solvent based coatings and screen printing ink.



PROPERTIES


assay: ≥99.5%
autoignition temp.: 669 °F
expl. lim.: 13.1 %
refractive index: n20/D 1.402 (lit.)
bp: 145-146 °C (lit.)
145-146 °C
solubility:
water: soluble 198 g/L at 20 °C
density: 0.970 g/mL at 25 °C (lit.)
Molecular Weight: 132.16 g/mol
Empirical Formula: C6H12O3
Appearance Colorless: Liquid
Freezing Point: -66°C (-87°F)
Flash Point: – Closed Cup 42°C (108°F)
Boiling Point: @ 760mmHg 146°C (295°F)
Autoignition Temperature: 333°C
Density: @ 20°C 0.967 kg/l, 8.07 lb/gal
Vapor Pressure: @ 20°C 2.8 mmHg
Evaporation Rate: (nBuAc = 1) 0.33
Solubility @ 20°C:
(in Water): 16%
(Water in): 3%
Refractive Index: @ 25°C 1.40
Viscosity: @ 25°C 0.8 cP
Surface Tension: @ 25°C 26.9 dynes/cm
Lower Flammability in Air: 1.5% v/v
Upper Flammability in Air: 7.0% v/v
Specific Heat: @ 25°C 1.85 J/g/°C
Heat of Vaporization: @ normal boiling point 296 J/g
Heat of Combustion: @ 25°C 23.8 kJ/g


Computed Properties:

Molecular Weight: 132.16
XLogP3-AA: 0.4
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 4
Exact Mass: 132.078644241
Monoisotopic Mass: 132.078644241
Topological Polar Surface Area: 35.5
Heavy Atom Count: 9
Formal Charge: 0
Complexity: 90.3
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes



FIRST AID

Propylene Glycol Methyl Ether Acetate may cause painful eye irritation and corneal injury.
Repeated or prolonged contact with the skin in very large amounts may cause localised irritation, and in some severe cases may cause drowsiness or dizziness.
High or repeated exposure via inhalation may lead to adverse effects to the nasal passages, liver and kidneys.

Unnecessary exposure should be prevented by appropriate work practices and engineering controls, adequate ventilation and by the use of approved personal protective equipment including gloves, clothing and safety goggles and the use of respirators where appropriate to the task being carried out.
Call for medical aid.


Eye Contact:

Wash with water for 15 min.
Call a physician.
Immediately flush with large amounts of water for at least 15 minutes, lifting upper and lower lids.
Remove contact lenses, if worn, while rinsing.


Skin Contact:

Remove contaminated clothing and wash contaminated skin with water.
Remove contaminated clothing and wash skin with soap and water.


Inhalation:

Remove the person from exposure.
Begin rescue breathing (using universal precautions) if breathing has stopped and CPR if heart action has stopped.
Transfer promptly to a medical facility.


Ingestion:

Induce vomiting after drinking two glasses of water.



HANDLING AND STORAGE


General industry practice is to store Propylene Glycol Methyl Ether Acetate in carbon steel vessels.
Storage in properly lined steel or stainless steel to avoid slight discoloration from carbon steel is recommended.

Product stored or delivered in unlined carbon steel vessels must be filtered due to technically unavoidable particles.
Propylene Glycol Methyl Ether Acetate should be stored under a nitrogen blanket when available.

Avoid contact with air when storing for long periods of time.
This product may absorb water if exposed to air.

Propylene Glycol Methyl Ether Acetate should be stored only in tightly closed, properly vented containers away from heat, sparks, open flame or strong oxidizing agents.
Use only non-sparkingtools.

Containers should be grounded before beginning transfer.
Electrical equipment should conform to national electric code.
Handle empty containers carefully.

Flammable combustible residue remains after emptying.
Propylene Glycol Methyl Ether Acetate that is subsequently repackaged, handled and/or delivered by third parties may have a different shelf life and may require third party shelf life studies.
Product past the retest date should be evaluated to confirm that all specifications are within their limits before use.

Propylene Glycol Methyl Ether Acetate and its vapours are combustible.
Thus, Propylene Glycol Methyl Ether Acetate should be stored in a cool, well-ventilated place away from sources of ignition and isolated from incompatible materials such as oxidizing agents.



SYNONYMS


1-Methoxy-2-propyl acetate, PMA, PGMEA, PM
Acetate
1-Methoxy-2-propyl acetate
108-65-6
1-methoxypropan-2-yl acetate
Propylene glycol monomethyl ether acetate
2-Acetoxy-1-methoxypropane
PGMEA
Propylene glycol methyl ether acetate
1-Methoxy-2-acetoxypropane
2-Methoxy-1-methylethyl acetate
2-Propanol, 1-methoxy-, acetate
METHOXYISOPROPYL ACETATE
1-METHOXY-2-PROPANOL ACETATE
Propyleneglycol monomethyl ether acetate
NSC 2207
Acetic acid, 2-methoxy-1-methylethyl ester
2-Propanol, 1-methoxy-, 2-acetate
EINECS 203-603-9
PROPYLENEGLYCOLMETHYLETHERACETATE
PA7O2U6S2Q
2-(1-Methoxy)propyl acetate
Propylene glycol 1-methyl ether 2-acetate
Propylene Glycol 1-Monomethyl Ether 2-Acetate
NSC-2207
Dowanol (R) PMA glycol ether acetate
UNII-PA7O2U6S2Q
BRN 1751656
AI3-18548
Arcosolv PMA
Dowanol PMA
MFCD00038500
2-Propanol, acetate
Ektasolve PM Acetate
propylene glycol monomethylether acetate
1,2-Propanediol monomethyl ether acetate
SU 8 DEVELOPER
DSSTox_CID_6796
EC 203-603-9
DSSTox_RID_78216
1-methoxy-2-acetoxy propane
DSSTox_GSID_26796
SCHEMBL15667
CHEMBL3182130
DTXSID1026796
HSDB 8443
LLHKCFNBLRBOGN-UHFFFAOYSA-
NSC2207
propyleneglycol methyl ether acetate
Tox21_201436
AKOS015837930
Glycol Ether PM Acetate Reagent Grade
METHOXYISOPROPYL ACETATE [INCI]
NCGC00249046-01
NCGC00258987-01
CAS-108-65-6
FT-0675939
P1171
1,2-Propanediol 1-Monomethyl Ether 2-Acetate
1,2-Propanediol monomethyl ether acetate, 99%
Propylene glycol monomethyl ether acetate(PMA)
Propylene glycol monomethyl ether acetate, 99%
EN300-1725866
J-504836
Q2170375
Propylene glycol monomethyl ether acetate, >=99.0% (GC)
Propylene glycol monomethyl ether acetate, ReagentPlus(R), >=99.5%
Propylene glycol monomethyl ether acetate, Vetec(TM) reagent grade
Propylene glycol 1-methyl ether 2-acetate 100 microg/mL in Acetonitrile
1,2-PROPANEDIOL 1-MONOMETHYL ETHER 2-ACETATE
1,2-PROPANEDIOL MONOMETHYL ETHER ACETATE
1-METHOXY-2-PROPANOL ACETATE
1-METHOXY-2-PROPYL ACETATE
2-(1-METHOXY)PROPYL ACETATE
2-ACETOXY-1-METHOXYPROPANE
2-METHOXY-1-METHYLETHYL ACETATE
2-(METHOXY)PROPYL ACETATE
ACETIC ACID 2-METHOXYPROPYL ESTER
ACETIC ACID METHOXYPROPYL ESTER
ARCOSOLV(R) PMA
DOWANOL(TM) PMA
GLYCOL ETHER PMA
MPA
PMA
PMA-EL
PROPYLENE GLYCOL 1-METHYL ETHER 2-ACETATE
PROPYLENE GLYCOL 1-MONOMETHYL ETHER 2-ACETATE
PROPYLENE GLYCOL METHYL ETHER ACETATE
PROPYLENE GLYCOL MONOMETHYL ETHER ACETATE
PROPYLENE GLYCOL METHYL ETHER ACETATE
cas no 5131-66-8 DOWANOL PNB; PGME;
PROPYLENE GLYCOL MONOBUTYL ETHER
Propylene glycol monobutyl ether (Propilen glikol monobütil eter) IUPAC Name 1-butoxypropan-2-ol Propylene glycol monobutyl ether (Propilen glikol monobütil eter) InChI InChI=1S/C7H16O2/c1-3-4-5-9-6-7(2)8/h7-8H,3-6H2,1-2H3 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) InChI Key RWNUSVWFHDHRCJ-UHFFFAOYSA-N Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Canonical SMILES CCCCOCC(C)O Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Molecular Formula C7H16O2 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) CAS 5131-66-8 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) European Community (EC) Number 225-878-4 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) ICSC Number 1614 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) RTECS Number UA7700000 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) DSSTox Substance ID DTXSID8027589 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Physical Description Liquid Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Boiling Point 171.5 °C Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Flash Point 63 °C c.c. Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Solubility Solubility in water, g/100ml: 6 (moderate) Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Density Relative density (water = 1): 0.879 (25 °C) Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Vapor Density Relative vapor density (air = 1): 4.55 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Vapor Pressure Vapor pressure, kPa at 25 °C: 0.187 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) LogP 1.15 (calculated) Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Atmospheric OH Rate Constant 3.76e-11 cm3/molecule*sec Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Autoignition Temperature 260 °C Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Viscosity 2.9 cSt at 25 °C Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Molecular Weight 132.2 g/mol Propylene glycol monobutyl ether (Propilen glikol monobütil eter) XLogP3-AA 1.1 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Hydrogen Bond Donor Count 1 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Hydrogen Bond Acceptor Count 2 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Rotatable Bond Count 5 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Exact Mass 132.11503 g/mol Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Monoisotopic Mass 132.11503 g/mol Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Topological Polar Surface Area 29.5 Ų Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Heavy Atom Count 9 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Formal Charge 0 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Complexity 54.9 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Isotope Atom Count 0 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Defined Atom Stereocenter Count 0 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Undefined Atom Stereocenter Count 1 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Defined Bond Stereocenter Count 0 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Undefined Bond Stereocenter Count 0 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Covalently-Bonded Unit Count 1 Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Compound Is Canonicalized Yes Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Industry Uses: Paint additives and coating additives not described by other categories,Processing aids, not otherwise listed,Solvents (for cleaning and degreasing),Solvents (which become part of product formulation or mixture),Surface active agents,insecticide - hornet & wasp.Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Consumer Uses: Cleaning and furnishing care products,Paints and coatings,Personal care products,insecticide hornet & wasp.Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Industry Processing Sectors:All other basic organic chemical manufacturing,All other chemical product and preparation manufacturing,Fabricated metal product manufacturing,Paint and coating manufacturing,Soap, cleaning compound, and toilet preparation manufacturing,Transportation equipment manufacturing.Propylene glycol monobutyl ether (Propilen glikol monobütil eter) Fire Hazards:Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Above 63 °C explosive vapour/air mixtures may be formed.Explosive limits , vol% in air: 1.1 (at 80 °C) - 8.4 (at 145 °C).Inhalation First Aid:Fresh air, rest.Skin First Aid:Rinse skin with plenty of water or shower.Eye First Aid:First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Then wash away with plenty of water.Keep in the dark. Separated from strong oxidants.No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.The substance is irritating to the eyes and skin.NO open flames. Above 63 °C use a closed system, ventilation and explosion-proof electrical equipment.Use ventilation.Protective gloves.Wear safety goggles.Do not eat, drink, or smoke during work.Propylene glycol monobutyl ether (Propilen glikol monobütil eter) (PNB) is a colorless liquid with an ether-like odor. It evaporates quickly and is hydrophobic (doesn’t mix well with water). Propylene glycol monobutyl ether (Propilen glikol monobütil eter) is a propylene oxide-based, or Pseries, glycol ether and a blend of two isomers: 1-butoxy-2-propanol (>95.0%, CAS# 5131-66-8), and 1-propanol-2-butoxy (<5.0%, CAS# 15821-83-7).® Propylene glycol monobutyl ether (Propilen glikol monobütil eter) is a clear, colorless having a mild characteristic odor. The principal end uses of Propylene glycol monobutyl ether (Propilen glikol monobütil eter) are industrial solvent, chemical intermediate, printing inks, paints and coatings. Propylene glycol monobutyl ether (Propilen glikol monobütil eter) should be stored only in tightly closed,properly vented containers away from heat, sparks,open flame or strong oxidizing agents. Use only nonsparking tools. Containers should be grounded before beginning transfer. Electrical equipment should conform to national electric code. Handle empty containers carefully. Flammable combustible residue remains after emptying.General industry practice is to store Propylene glycol monobutyl ether (Propilen glikol monobütil eter)P in carbon steel vessels. Storage in properly lined steel or stainless steel to avoid slight discoloration from mild steel is recommended. Avoid contact with air when storing for long periods of time. This product may absorb water if exposed to air.Provided proper storage and handling precautions are taken, Propylene glycol monobutyl ether (Propilen glikol monobütil eter) manufactured and delivered.Monument Chemical is stable for at least 12 months from the date of manufacture. Propylene glycol monobutyl ether (Propilen glikol monobütil eter) that is subsequently repackaged, handled and/or delivered by third parties may have a different shelf life and may require third party shelf life studies. Product past theretest date should be evaluated to confirm that all specifications are within their limits before use. Propylene series glycol ethers are used in surface coatings, leather, pesticides, electrical, industrial cleaners, resins, and printing inks; [ECETOC] Used as a coupling agent and solvent (degreasers, paint removers, metal cleaners, and hard surface cleaners), coalescent (latex coatings), coupling agent (water-based agricultural formulations), and chemical intermediate (epoxides, acid ester derivatives, solvents, and plasticizers).Adverse effects in animal studies include adaptive liver changes and reversible CNS depression, but no hematological, genotoxic, or carcinogenic effects; [ToxPlanet: ECETOC] A skin and eye irritant; [ICSC] May cause moderate skin and eye irritation; May cause mild, reversible corneal injury;"Dipropylene glycol n-butyl ether."But for its Elements glass cleaner, part of a line it calls “environmentally responsible maintenance solutions,” Misco has replaced EGBE with a blend of diethylene glycol monobutyl ether and propylene glycol mono n-butyl ether. Unlike EGBE, these glycol ethers aren’t readily absorbed by the skin and aren’t associated with blood cell breakage, the firm says.Misco is using propylene-based glycol ethers—so-called P-series glycol ethers—to replace EGBE in most of the new products it develops, according to Zhou. The catch, he says, is that there’s no one drop-in replacement for EGBE. The company often must tailor blends out of propylene glycol monopropyl ether, dipropylene glycol monopropyl ether, propylene glycol mono n-butyl ether, and dipropylene glycol mono n-butyl ether.Propylene glycol ethers are a class of solvents used in a wide array of industrial, commercial and consumer applications, such as in paints, cleaners and inks. A robust toxicity database exists for the propylene glycol ethers that provide strong product safety support. Standard toxicity studies conducted under good laboratory practices indicate a lack of genotoxic, developmental and reproductive hazards. Recent testing efforts have primarily focused in two areas: (1) examination of the chronic toxicity/oncogenicity potential of propylene glycol monomethyl ether (PGME) in rats and mice and (2) expansion of the developmental toxicity database to higher molecular weight P-series glycol ether derivatives (i.e. propylene glycol n-propyl ether (PGPE), Propylene glycol monobutyl ether (Propilen glikol monobütil eter) (PGBE) and dipropylene glycol n-butyl ether (DPGBE)). In PGME chronic toxicity/oncogenicity studies no treatment-related increases in the incidence of tumors occurred in either species. Like other previously tested P-series derivatives, PGPE, PGBE and DPGBE were negative in rodent and rabbit developmental toxicity studies. Collectively, the toxicity database for P-series glycol ether products continues to support the lack of significant health effects with proper use of the commercial products.This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.This substance is used in the following products: washing & cleaning products, coating products, inks and toners, plant protection products and cosmetics and personal care products.Other release to the environment of this substance is likely to occur from: indoor use as processing aid and outdoor use as processing aid.Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment). Propylene glycol monobutyl ether (Propilen glikol monobütil eter) glycol ether is a fast evaporating, hydrophobic solvent which is extensively used in heavy-duty cleaning formulations. It does an excellent job of solvating and coupling hydrophobic greases and oils in household as well as industrial formulations. It is partly water soluble and miscible with most organic solvents. Propylene glycol monobutyl ether (Propilen glikol monobütil eter) glycol ether also provides excellent surface-tension lowering ability. In coatings Propylene glycol monobutyl ether (Propilen glikol monobütil eter) offers good coalescing ability in systems requiring fast evaporation.Uses for Propylene Glycol Butyl Ether:Coupling agent and solvent in household and industrial cleaners, grease and paint removers, metal cleaners, and hard surface cleaners.Effective coupling agent and efficient solvent for water-reducible coatings.Effective coalescent for lowering minimum film formation temperature (MFFT) in water-borne latex coatings.Active solvent for solvent-based coatings.Chemical intermediate for the production of epoxides, acid ester derivatives, solvents, and plasticizers.Effective coupling agent in waterbased agricultural formulations.Features of Propylene Glycol Butyl Ether.Excellent solvency.Good oil solubility.Effective surfactant properties.Excellent coupling ability.Good evaporation rate control.Greater formulating flexibility.Low viscosity.Wide range of applications.Low toxicity.Practical alternative to Butyl glycol.Colourless liquid. Propylene glycol monobutyl ether (Propilen glikol monobütil eter) is mainly used as cleaning agent for heavy contaminant. It can dissolve coupling oil and grease efficiently and make itself suitable for the formula of household and industrial. Partially soluble in water, Propylene glycol monobutyl ether (Propilen glikol monobütil eter) can solubilize most solvent with the application as follows: ① as household and industrial cleanser, remover of grease and paint, coupling agent and solvent of metal and hard surface cleanser; ② as effective coupling agent and solvent of water-reducing coatings; ③ as effective coagulating agent of water-based emulsion paint; ④ as active solvent of solvent-based paint; ⑤ as chemical intermediate for ester, solvent and plasticizer manufacture.Application in coating: as one of the best film-forming auxiliaries of water-based paints, D Propylene glycol monobutyl ether (Propilen glikol monobütil eter) can be used as coagulant of acrylic resin, phenylethylene acrylic resin and polyvinyl acetate giving excellent performance to paint film.Application in cleanser: it is applicable to cleaning agents especially for those which require low volatile speed, such as wax remover and floor cleanser. As good coupling agent for lubricating grease and fat, D Propylene glycol monobutyl ether (Propilen glikol monobütil eter) can be applied as paint stripper and remover of animal fat.Other application: D Propylene glycol monobutyl ether (Propilen glikol monobütil eter) can also be used in agricultural products, cosmetics, electronic ink and textile.The alpha (secondary alcohol) form is kinetically favored during synthesis. Propylene glycol monobutyl ether (Propilen glikol monobütil eter) is available as the isomeric mixture in which the alpha isomer is the predominant isomer (ca. 95%. DPnB, DPMA and TPM are commercially produced as mixtures of isomeric components in which the internal ether linkages may be adjacent to either primary or secondary carbon atoms. Thus, for DPMA and DPnB the commercially produced products may contain up to 4 such isomers. In the case of TPM, the commercially produced product may contain up to 8 such isomers. This category of propylene glycol ethers (PGEs) exhibits low acute toxicity by the oral, dermal, and inhalation routes.Rat oral LD50s range from >3,000 mg/kg ( Propylene glycol monobutyl ether (Propilen glikol monobütil eter)) to >5,000 mg/kg (DPMA). Dermal LD50s are all > 2,000 mg/kg ( Propylene glycol monobutyl ether (Propilen glikol monobütil eter), & DPnB; where no deaths occurred), and ranging up to >15,000 mg/kg (TPM). Inhalation LC50 values were higher than 5,000 mg/m3 for DPMA (4-hour exposure), and TPM (1-hour exposure). For DPnB the 4-hour LC50 is >2,040 mg/m3. For Propylene glycol monobutyl ether (Propilen glikol monobütil eter), the 4-hour LC50 was >651 ppm (>3,412 mg/m3), representing the highest practically attainable vapor level. No deaths occurred at these concentrations for any of the four new category members. Propylene glycol monobutyl ether (Propilen glikol monobütil eter) and TPM are moderately irritating to eyes while the remaining category members are only slightly irritating to nonirritating. Propylene glycol monobutyl ether (Propilen glikol monobütil eter) is moderately irritating to skin while the remaining category members are slightly to non-irritating.None of the category members are skin sensitizers. In repeated dose studies ranging in duration from 2 to 13 weeks, few adverse effects were found even at high exposure levels and effects that did occur were mild in nature. By the oral route of administration, NOAELs of 350 mg/kg-d ( Propylene glycol monobutyl ether (Propilen glikol monobütil eter) – 13 wk) and 450 mg/kg-d (D Propylene glycol monobutyl ether (Propilen glikol monobütil eter) – 13 wk) were observed for liver and kidney weight increases (without accompanying histopathology). LOAELs for these two chemicals were 1000 mg/kg-d (highest dose tested).Dermal repeated-dose toxicity tests have been performed for all of the category members but DPMA. For Propylene glycol monobutyl ether (Propilen glikol monobütil eter), no effects were seen in a 13-wk study at doses as high as 1,000 mg/kg-d. A dose of 273 mg/kg-d constituted a LOAEL (increased organ weights without histopathology) in a 13-week dermal study for D Propylene glycol monobutyl ether (Propilen glikol monobütil eter). For TPM, increased kidney weights (no histopathology) and transiently decreased body weights were found at a dose of 2,895 mg/kg-d in a 90-day study in rabbits. By inhalation, no effects were observed in 2-week studies in rats at the highest tested concentrations of 3244 mg/m3 (600 ppm) for Propylene glycol monobutyl ether (Propilen glikol monobütil eter) and 2,010 mg/m3 (260 ppm) for D Propylene glycol monobutyl ether (Propilen glikol monobütil eter). TPM caused increased liver weights without histopathology by inhalation in a 2-week study at a LOAEL of 360 mg/m3 (43 ppm). In this study, the highest tested TPM concentration, 1010 mg/m3 (120 ppm), also caused increased liver weights without accompanying histopathology. Although no repeated-dose studies are available for the oral route for TPM, or for any route for DPMA, it is anticipated that these chemicals would behave similarly to other category members. Propylene glycol monobutyl ether (Propilen glikol monobütil eter) (PnB): Because of high solvency, oil solubility, surfactant, and coupling properties, and due to good evaporation rate control, high formulating flexibility, low viscosity, as well as low toxicity, PnB may be used as a coupling agent and solvent in domestic and commercial cleaning solutions such as degreasers, paint removers, metal cleaners, and hard surface cleaners. These characteristics also allow PnB to be used as a coupling agent in water-based agricultural formulations, facilitating the homogenous blending of ingredients with diverse solubility characteristics. Propylene glycol monobutyl ether (Propilen glikol monobütil eter) is also used as a coalescent for lowering minimum film formulation temperature (MFFT) in water-borne latex coatings and as a chemical intermediate for the production of epoxides, acid ester derivatives, solvents, and plasticizers. Regarding skin and eye irritation, the dataset summarized in Table 8 is complete for the category.Some of the chemicals may be moderately irritating to eyes. All but Propylene glycol monobutyl ether (Propilen glikol monobütil eter) are slightly or nonirritating to skin. Undiluted Propylene glycol monobutyl ether (Propilen glikol monobütil eter) may be moderately irritating to skin. The acetates show either no or moderate potential for irritation to either eyes or skin. Propylene glycol n-butyl ether (PnB) was applied daily (5 days/week) for 13 weeks to the skin of four groups of New Zealand White rabbits (5/sex/dose level) at various dilutions in a 50/50 v/v mixture of ethanol and water (vehicle), equivalent to volumetric PnB doses of 0 (vehicle-only), 11.4, 114,or 1140 µl/kg-day (total dose volume of 2 ml/kg-day). These doses corresponded to dilutions of 0, 0.569%, 5.69, or 56.9% (w/v) of PnB in the treatment solution. When adjusted for the density of PnB, the volumetric doses equate to mass doses of 0, 1, 100, or 1000 mg PnB/kg-day.Treatment solutions were applied to the clipped dorsal trunk of each rabbit.Rabbits wore collars to prevent grooming and ingestion of test material.Solutions were applied unoccluded since the low vapor pressure of PnB was assumed to precluded evaporative loss. Propylene glycol n-butyl ether did not cause claustogenic damage to nuclear material in rat hepatocytes at any dose level, with or without metabolic activation.The alpha (secondary alcohol) form is kinetically favored during synthesis. PnB is available as the isomeric mixture in which the alpha isomer is the predominant isomer (ca. 95%. DPnB, DPMA and TPM are commercially produced as mixtures of isomeric components in which the internal ether linkages may be adjacent to either primary or secondary carbon atoms. Thus, for DPMA and DPnB the commercially produced products may contain up to 4 such isomers. In the case of TPM, the commercially produced product may contain up to 8 such isomers. This category of propylene glycol ethers (PGEs) exhibits low acute toxicity by the oral, dermal, and inhalation routes. Rat oral LD50s range from >3,000 mg/kg (PnB) to >5,000 mg/kg (DPMA). Dermal LD50s are all > 2,000 mg/kg (PnB, & DPnB; where no deaths occurred), and ranging up to >15,000 mg/kg (TPM). Inhalation LC50 values were higher than 5,000 mg/m3 for DPMA (4-hour exposure), and TPM (1-hour exposure). For DPnB the 4-hour LC50 is >2,040 mg/m3. For PnB, the 4-hour LC50 was >651 ppm (>3,412 mg/m3 ), representing the highest practically attainable vapor level. No deaths occurred at these concentrations for any of the four new category members. PnB and TPM are moderately irritating to eyes while the remaining category members are only slightly irritating to nonirritating. PnB is moderately irritating to skin while the remaining category members are slightly to non-irritating. None of the category members are skin sensitizers. In repeated dose studies ranging in duration from 2 to 13 weeks, few adverse effects were found even at high exposure levels and effects that did occur were mild in nature. By the oral route of administration, NOAELs of 350 mg/kg-d (PnB – 13 wk) and 450 mg/kg-d (DPnB – 13 wk) were observed for liver and kidney weight increases(without accompanying histopathology). LOAELs for these two chemicals were 1000 mg/kg-d (highest dose tested).Dermal repeated-dose toxicity tests have been performed for all of the category members but DPMA. For PnB, no effects were seen in a 13-wk study at doses as high as 1,000 mg/kg-d. A dose of 273 mg/kg-d constituted a LOAEL (increased organ weights without histopathology) in a 13-week dermal study for DPnB. For TPM, increased kidney weights (no histopathology) and transiently decreased body weights were found at a dose of 2,895 mg/kg-d in a 90- day study in rabbits. By inhalation, no effects were observed in 2-week studies in rats at the highest tested concentrations of 3244 mg/m3 (600 ppm) for PnB and 2,010 mg/m3 (260 ppm) for DPnB. TPM caused increased liver weights without histopathology by inhalation in a 2-week study at a LOAEL of 360 mg/m3 (43 ppm). In this study, the highest tested TPM concentration, 1010 mg/m3 (120 ppm), also caused increased liver weights without accompanying histopathology. Although no repeated-dose studies are available for the oral route for TPM, or for any route for DPMA, it is anticipated that these chemicals would behave similarly to other category members. One and two-generation reproductive toxicity testing has been conducted in mice, rats, and rabbits via the oral or inhalation routes of exposure on PM and PMA. In an inhalation rat study using PM, the NOAEL for parental toxicity is 300 ppm (1106 mg/m3) with decreases in body and organ weights occurring at the LOAEL of 1000 ppm (3686mg/m3). For offspring toxicity the NOAEL is 1000 ppm (3686 mg/m3), with decreased body weights occurring at 3000 ppm (11058 mg/m3). For PMA, the NOAEL for parental and offspring toxicity is 1000 mg/kg/d. in a twogeneration gavage study in rats. No adverse effects were found on reproductive organs, fertility rates, or other indices commonly monitored in such studies. In addition, there is no evidence from histopathological data from repeated-dose studies for the category members that would indicate that these chemicals would pose a reproductive hazard to human health.The Propylene Glycol Ethers Category consists of four new members: propylene glycol n-butyl ether, or PnB (CAS No. 5131-66-8); dipropylene glycol n-butyl ether, or DPnB (CAS No. 29911- 28-2); dipropylene glycol methyl ether acetate, or DPMA (CAS No. 88917-22-0); and tripropylene glycol methyl ether, or TPM (CAS No. 25498-49-1 and 20324-33-8). These chemicals form a category based on similar structural, physicochemical, and toxicological properties. Propylene glycol ethers may appear in two isomeric forms. The predominant form consists of a secondary alcohol (also sometimes referred to as the alpha isomer) and a minor form (the beta isomer), consisting of a primary alcohol. This distinction has toxicological significance as will be discussed later. Three glycol ethers used to support the category and are also part of the category are: propylene glycol methyl ether, or PM (CAS No. 107-98-2); propylene glycol methyl ether acetate, or PMA (CAS No. 108-65-6); and dipropylene glycol methyl ether, or DPM (CAS No. 34590-94-8). Data from these are used to fill data gaps of category members. These glycol ethers are considered as category members due to their structural and toxicological similarities. These three chemicals were evaluated at SIAM 11 and 12 and found to be low priority for further testing. The details and references for each study selected are given in the robust summary/dossier sets for each category member. There are some inconsistencies in how chemicals are reported throughout the world and what CAS numbers are used. It should be noted that in the original IUCLID dossiers, some studies that were conducted using the commercial mixtures had incorrectly used CAS numbers that are specific to the alpha isomer. However, testing was usually carried out on the commercially produced products that were nominated as HPV chemicals, all of which are mixtures containing at least a minimal amount of beta isomer (usually less than 5%); rarely, when noted in the IUCLID, the study may have been conducted on a more purified form of either the alpha or beta isomer. Unless specifically stated in the dossiers, the purified beta isomer was not tested. Please see Annex I for a more detailed discussion of these issues. Where n = 1, 2, or 3 and R = alkyl (methyl or n-butyl). In addition, in the case of the acetates, DPMA and PMA, an acetate moiety is substituted for the hydrogen atom on the free hydroxyl group. Under physiological conditions, this acetate moiety is easily separated from the oxygen atom of the alcohol by the process of hydrolysis to yield the parent ether and acetic acid. Structures of the individual isomers are shown in Annex I along with their Chemical Abstract Service (CAS) numbers. Annex I also explains the nature of the mixtures of isomers more completely and shows the molecular structures of the predominant isomers, illustrating their close structural similarity. The reader is advised to read Annex I for questions regarding the chemical nature of propylene glycol ethers. With regard to the category member, dipropylene glycol ether acetate (DPMA), research on the close structural analogue, monopropylene glycol ether acetate (PMA), by Domoradzki (2001) as cited in Corley et al. (2003), showed that this PGE acetate is hydrolyzed to its parent ether in vivo with a half-life of 1.6 to 3.4 minutes. These researchers showed that the pharmacokinetics of PMA were indistinguishable from PM when PMA was infused intravenously. Hydrolysis is attributed to naturally occurring esterases present in blood and other tissues. In an older study, Miller et al., (1984) showed that the metabolism and disposition of PMA in male Fischer 344 rats was practically indistinguishable from PM. Hoffmann and Jackh (1985) showed that the beta isomer of PMA hydrolyzed in vitro to the free ether in rat plasma with a half-life of 0.64 minutes. Thus, it is appropriate to include the acetate in this category of chemicals due to its rapid conversion to its parent ether and nearly identical toxicity. Note that all of the monopropylene glycol ethers may exist in two isomeric forms, alpha or beta.The alpha form, which is thermodynamically favored during synthesis, consists of a secondary alcohol configuration. The beta form consists of a primary alcohol. The two isomeric forms are shown above. The di- and tripropylene glycol ethers may form up to 4 and 8 isomeric forms, respectively. Even so, all isomers exhibit either the “alpha” or “beta” configuration, existing as secondary or primary alcohols, respectively. The distribution of isomeric forms for the di- and tripropylene glycols, as with the mono-PGEs, also results in predominantly the alpha form (i.e., a secondary alcohol). It should be noted that only the alpha isomer and isomeric mixtures (consisting predominantly of the alpha isomer) are produced commercially; the purified beta isomer is not produced at this time. Testing of a wide variety of propylene glycol ethers has shown that propylene glycol-based ethers are less toxic than some ethers of the ethylene series. The common toxicities associated with the lower molecular weight homologues of the ethylene series, such as adverse effects on reproductive organs, the developing embryo and fetus, blood (hemolytic effects), or thymus, are not seen with the commercial-grade propylene glycol ethers. In the ethylene series, metabolism of the terminal hydroxyl group produces an alkoxyacetic acid (Patty’s Toxicology, 5th Ed., 2001). Thereproductive and developmental toxicities of the lower molecular weight homologues in the ethylene series are due specifically to the formation of methoxyacetic and ethoxyacetic acids.Longer chain length homologues in the ethylene series are not associated with the reproductive toxicity but can cause hemolysis in sensitive species, also through formation of an alkoxyacetic acid. The predominant alpha isomer of all the propylene glycol ethers (thermodynamically favored during manufacture of PGEs) is a secondary alcohol incapable of forming an alkoxy propionic acid.This alpha isomer comprises greater than 95% of the isomeric mixture in the commercial product.Because the alpha isomer cannot form an alkoxypropionic acid, this is the most likely reason for the lack of toxicity shown by the propylene glycol ethers as distinct from the lower molecular weight ethylene glycol ethers. More importantly, however, very extensive empirical test data show thatthis class of commercial-grade glycol ether presents a low toxicity hazard. Propylene glycol ethers,whether mono, di- or tripropylene glycol-based (and no matter what the alcohol group), show a verysimilar pattern of low to non-detectable toxicity of any type at doses or exposure levels greatlyexceeding those showing pronounced effects from the ethylene series. One of the primary metabolites of the propylene glycol ethers is propylene glycol, which is of low toxicity and completely metabolized in the body.
PROPYLENE GLYCOL MONOBUTYL ETHER (SOLVENON PNB)
1-Methoxy-2-propanol; PGME; 1-Methoxypropan-2-ol; polypropylene glycol methyl ether; propylene glycol 1-methyl ether; PM; (+/-)-1-methoxy-2-propanol; 1-Methoxy-2-hydroxypropane; Methoxy Propanol; 2-Methoxy- 1 -Methyl Ethanol; cas no: 107-98-2
PROPYLENE GLYCOL MONOMETHYL ETHER (SOLVENON PM)
propan-2-ol, 1-butoxy-; 1-Butoxy-2-propanol; n-Butoxypropanol CAS NO:5131-66-8
Propylene Glycol n-Butyl Ether
Propylheptyl caprylate; 2-propylheptyl Octanoate; 2-Propylheptyl caprylate; 868839-23-0; Cetiol Sensoft cas no: 868839-23-0
PROPYLENE GLYCOL N-BUTYL ETHER
CAS No: 5131-66-8
EC Number: 225-878-4
Molecular Weight: 132.20 g/mol

DESCRIPTION:
Propylene Glycol N-Butyl Ether is a green senior solvent, widely used in coatings, cleaning agents, inks, leather, etc.
Because of low toxicity and pleasant smell, Propylene Glycol N-Butyl Ether is a promising environmentally friendly solvents.
Propylene Glycol N-Butyl Ether is highly safe in industrial / household detergent formulations.
As the HLB value is in the middle of water / oil, there is great room for growth in paint / ink / detergent formulations.

Propylene Glycol N-Butyl Ether is a clear, colorless having a mild characteristic odor.
The principal end uses of Propylene Glycol N-Butyl Ether are industrial solvent, chemical intermediate, printing inks, paints and coatings

Propylene Glycol N-Butyl Ether glycol ether is a fast evaporating, hydrophobic solvent which is extensively used in heavy-duty cleaning formulations.
Propylene Glycol N-Butyl Ether does an excellent job of solvating and coupling hydrophobic greases and oils in household as well as industrial formulations.

Propylene Glycol N-Butyl Ether is partly water soluble and miscible with most organic solvents.
Propylene Glycol N-Butyl Ether glycol ether also provides excellent surface-tension lowering ability.
In coatings Propylene Glycol N-Butyl Ether offers good coalescing ability in systems requiring fast evaporation

Propylene Glycol N-Butyl Ether is a solvent that can be found in common household kitchen cleaners.
Propylene Glycol N-Butyl Ether is used as a cleaning agent that helps dissolve grease and soil from surfaces.

Propylene Glycol N-Butyl Ether possesses an ether-like odor and is composed of a colorless liquid.
Propylene Glycol N-Butyl Ether evaporates rapidly, and is not water soluble.
Propylene Glycol N-Butyl Ether is primary application is in heavy-duty cleaning formulations, but Propylene Glycol N-Butyl Ether is also used as a solvent, chemical intermediate, coalescing agent, and as a coupling agent.
Propylene Glycol N-Butyl Ether is also readily biodegradable and unlikely to accumulate in the food chain, as well as practically non-toxic to fish and other aquatic organisms.

However, Propylene Glycol N-Butyl Ether is highly combustible as both a liquid and in vapor form, though Propylene Glycol N-Butyl Ether is stable under recommended storage conditions.
Additionally, Propylene Glycol N-Butyl Ether is incompatible with most strong acids, strong bases, and strong oxidizers, and any contact with these substances should be avoided.
Eye or skin contact with Propylene Glycol N-Butyl Ether may cause moderate irritation, and in the case of eye contact can cause slight corneal injury.
However, prolonged contact with skin is unlikely to cause any significant or harmful absorption.







CHEMICAL AND PHYSICAL PROPERTIES OF PROPYLENE GLYCOL N-BUTYL ETHER:

CAS No: 5131-66-8
purity %: ≥99.5
Molecular formula: C7H16O2
Appearance: Colorless liquid
Boiling point ℃: 171.1
Density (g/cm3): 0.879
Flash point ℃: 68
Acid value mgKOH/g: <0.10
Color(Pt-Co): ≤20
Water content %: <0.10
Assay: ≥99%
Composition: (mixture of isomers)
refractive index: n20/D 1.416 (lit.)
bp: 165-175 °C (lit.)
Density: 0.885 g/mL at 25 °C
Molecular Weight: 132.2 g/mol
Empirical Formula: C7H16O2
Appearance: Colorless
Freezing Point: -85°C (-121°F)
Flash Point – Closed Cup: 68.9°C (156°F)
Boiling Point @ 760mmHg :171°C (340°F)
Autoignition Temperature :260°C (500°F)
Density @ 20°C :
0.879 kg/l
7.34 lb/gal
Vapor Pressure @ 25°C: 1.1 mmHg
Evaporation Rate (nBuAc = 1) :0.09
Solubility @ 20°C (in Water) :5.5 wt%
Refractive Index @ 25°C: 1.420
Viscosity @ 25°C: 3.9 cP
Surface Tension @ 25°C :27 mN/m
Lower Flammability in Air :1.1% v/v
Upper Flammability in Air: 9.0% v/v
Specific Heat @ 25°C: 1.98 J/g/°C
Heat of Vaporization @ normal boiling point:320 J/g
Heat of Combustion @ 25°C :31.4 kJ/g
Formula:C4H9OCH2CH(CH3)OH
CAS No: 5131-66-8
Molar mass: 132.2 g mol
Density: 0.878 g/cm, liquid
Boiling Point: 171 C
Flash Point: 63 C
Autoignition Temperature: 260 C
Viscosity: 3.1 cP at 25 C
Solubility in water: 5.5g per 100g
Other Names: Dowanol PnB, Propylene glycol normal butyl ether,
Vapor Pressure: 0.444000 mmHg @ 25.00 °C. (est)
Flash Point: 130.00 °F. TCC ( 54.50 °C. ) (est)
logP (o/w): 1.187 (est)

FEATURES OF PROPYLENE GLYCOL N-BUTYL ETHER:
Propylene Glycol N-Butyl Ether has Excellent solubility and good oil solubility;
Propylene Glycol N-Butyl Ether has Excellent surface and coupling properties;
Propylene Glycol N-Butyl Ether has Low viscosity, low odor, low toxicity.

APPLICATIONS OF PROPYLENE GLYCOL N-BUTYL ETHER:
Coating: Propylene Glycol N-Butyl Ether can be used as a solvent-based coating solvent, or water-based cosolvent, excellent performance on film smooth, adhesion
Ink: Can changed formulas to water-soluble one to meet the environmental requirements : reduce the toxicity, improve the operating environment and product quanlity
Dye: To replace alcoholic series solvents, as a good coupling agent;

Cleaner: Propylene Glycol N-Butyl Ether can be prepared as concentrated cleaning agents with excellent performance
Brake fluid: main components ,the max proportion 40%
Others: Propylene Glycol N-Butyl Ether can also be used for colorful paint, photographic glue, PS plate cleaning, printing, electronic chemicals, jet fuel additive (waterproofing agent), extractant and high boiling point solvent.
Household and industrial cleaning of coupling agents and solvents, paint remover, cleaning agents.





USES OF PROPYLENE GLYCOL N-BUTYL ETHER:
Propylene Glycol N-Butyl Ether is used in surface coatings, leather, pesticides, electrical, industrial cleaners, resins, and printing inks
Propylene Glycol N-Butyl Ether is Used as a coupling agent and solvent (degreasers, paint removers, metal cleaners, and hard surface cleaners), coalescent (latex coatings), coupling agent (water-based agricultural formulations), and chemical intermediate (epoxides, acid ester derivatives, solvents, and plasticizers)

Propylene Glycol N-Butyl Ether is Used as Coupling agent and solvent in household and industrial cleaners, grease and paint removers, metal cleaners, and hard surface cleaners.
Propylene Glycol N-Butyl Ether is Used as Effective coupling agent and efficient solvent for water-reducible coatings.

Propylene Glycol N-Butyl Ether is Used as Effective coalescent for lowering minimum film formation temperature (MFFT) in water-borne latex coatings.
Propylene Glycol N-Butyl Ether is Used as Active solvent for solvent-based coatings.
Propylene Glycol N-Butyl Ether is Used as Chemical intermediate for the production of epoxides, acid ester derivatives, solvents, and plasticizers.
Propylene Glycol N-Butyl Ether is Used as Effective coupling agent in water based agricultural formulations.


SAFETY INFORMATION ABOUT PROPYLENE GLYCOL N-BUTYL ETHER:

First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.













SYNONYMS OF PROPYLENE GLYCOL N-BUTYL ETHER:
Butoxypropanol
1,2-Propylene glycol 1-monobutyl ether
1-Butoxy-2-propanol
2-Hydroxy-3-butoxypropane
Propasol solvent B
Propylene glycol monobutyl ether
n-Butoxy-2-propanol
n-Butoxypropanol
1-Butoxypropan-2-ol
2-Propanol, 1-butoxy-
PnB
Dowanol PNB glycol ether
PGBE
1,2-Propylene Glycol 1-Monobutyl Ether
1-Butoxy-2-Propanol
1-Butoxypropan-2-ol
2-Propanol, 1-Butoxy-
3-Butoxypropan-2-ol
Butoxyisopropanol
Éter Monobutil del Propilenglicol (Spanish)
Éther n-Butylique du Propylène Glycol (French)
Propylene Glycol Butyl Ether (IFRA)
Propylene Glycol Butyl Ether (INCI)
Propylene Glycol Monobutyl Ether
Propylene Glycol n-Butyl Ether