PEG-150 Distearate is a polyethylene glycol diester of stearic acid.
PEG-150 distearate is a cleansing agent.
PEG 150 Distearate is a white-light granular powder.
PEG 150 Distearate's Solubility can be dissolved in water with heat.


CAS Number: 9005-08-7
Molecular Formula-C19H40O4
Chemical Function: Thickener


PEG 150 Distearate has garnered appreciation for its widespread use in personal care products, cosmetics, paints, and dyes.
PEG 150 Distearate is produced by the esterification of stearic acid which is derived from palm kernel oil or other vegetable oils.
PEG 150 Distearate works by acting as a solubilizer for water-insoluble ingredients.
PEG 150 Distearatereduces the surface tension of the substances and helps form emulsions.


PEG 150 Distearate is soluble in water and ethanol and is insoluble in vegetable and mineral oil.
Mixing method of PEG 150 Distearate: mix in water or in the detergent part reheat them to melt and stir to combine
PEG 150 Distearate is the Polyethylene GlycolDiester of Stearic Acid
PEG 150 Distearate is white flake, characteristic odor, slightly cloudy in water, clear in surfactant-containing solutions.


PEG 150 Distearate is an ester made from the reaction of vegetable-derived triple-pressed grade stearic acid and a defined high molecular weight polyethylene glycol.
PEG-150 Distearate is a polyethylene glycol diester of stearic acid.
PEG 150 Distearate is a water-soluble nonionic surfactant and thickener which is ideally suited to add a soft, silky after-feel to skin cleansing products.


PEG 150 Distearate is defined as the polyethylene glycol (PEG) diester of stearic acid, wherein the PEG has an average degree of polymerization of 150 oxyethylene repeat units corresponding to an average molecular weight (MW) of 6,600 g/mol.
The overall average MW of PEG 150 Distearate is 7,170 g/mol—sufficiently high enough to categorize the ingredient as a low MW polymer.
PEG 150 Distearate is a telechelic polymer, i.e., it is functionalized with a hydrophobic stearate ester on both the α and ω ends of the hydrophilic PEG chain so that both ends of the polymer exhibit surface and interfacial activity.


Polyethylene Glycol (PEG) Distearates are produced from stearic acid, a naturally occurring fatty acid, which occurs in animal fats and
oils.
PEG Distearates are manufactured by reacting stearic acid with a specific number of units of ethylene oxide which corresponds to the average PEG chain length desired.


When associated to etoxilated fatty alcohols PEG 150 Distearate shows a special synergy that allows that alkanol amides be partially or totally substituted.
PEG 150 Distearate should be added under agitation to the water of formulation – total or part of the water – at 70-80°C.
In cold processing, PEG 150 Distearate must be previously dissolved before incorporate it to the formulation.
It is better elaborate an aqueous solution at 10% and heat this solution until 70-80°C or PEG 150 Distearate can be solubilized in the amide associated to an amphoteric, heating to 65-75°C.


After this step, the cold processing can continue.
PEG 150 Distearate is an ester made from the reaction of vegetable-derived triple-pressed grade stearic acid.
In addition PEG 150 Distearate is a defined high molecular weight polyethylene glycol.
PEG-150 Distearate is a Polyethylene glycol diester of stearic acid.


PEG 150 Distearate is a white flake, a characteristic odor, slightly cloudy in water, and clear in surfactant-containing solutions.
PEG 150 Distearate is soluble in water.
PEG 150 Distearate is an effective thickener for surfactant-containing products (e.g. shampoo, conditioner, shower gels), a solubilizer for various water-insoluble ingredients, and has good co-emulsifying properties in creams & lotions.


Use PEG 150 Distearate heated to 60°C (140°F) when incorporated into formulas.
PEG 150 Distearate is a polyethylene glycol diester of stearic acid. PEG 150 Distearate's HLB is 18.9 (gives oil-in-water emulsions).
PEG 150 Distearate appears slightly cloudy in water, but clear in surfactant-containing solutions.
PEG 150 Distearate is produced by the esterification of stearic acid which is derived from palm kernel oil or other vegetable oils.


PEG 150 Distearate is Polyethylene glycol diester of stearic acid.
PEG 150 Distearate appears slightly cloudy in water, but clear in surfactant-containing solutions.
PEG-150 Distearate is a polyethylene glycol diester of stearic acid.
PEG-150 Distearate is polyethylene glycol diester of stearic acid.


PEG 150 Distearate is general emulsifier.
PEG 150 Distearate is hydrophilic ester type surfactant with excellent emulsification.
PEG 150 Distearate is an emulsifier for creams and lotions, especially for systems containing high concentrations of electrolytes.
PEG 150 Distearate is not considered to be an irritant or sensitizer, and is CIR and FDA approved for use, but not on broken skin.


The PEG Distearate ingredients (PEG-2 Distearate, PEG-3 Distearate, PEG-4 Distearate, PEG-6 Distearate, PEG-8 Distearate, PEG-9 Distearate, PEG-12 Distearate, PEG-20 Distearat, PEG-32 Distearate, PEG-75 Distearate, PEG-120 Distearate, PEG-150 Distearate, PEG-175 Distearate) range from liquids to solids or flakes.


In cosmetics and personal care products, PEG Distearate ingredients are used in the formulation of shampoos, hair conditioners, personal cleanliness products, bath products, and skin care and skin cleansing products.
Polyethylene Glycol (PEG) Distearates are produced from stearic acid, a naturally occurring fatty acid, which occurs in animal fats and oils.
PEG Distearates are manufactured by reacting stearic acid with a specific number of units of ethylene oxide which corresponds to the average PEG chain length desired.



USES and APPLICATIONS of PEG 150 DISTEARATE:
PEG 150 Distearate Applications: Baby Care, Bath & Shower, Skin Care, Skin Cleansing.
PEG 150 Distearate is an emulsifier and potent thickener for surfactant systems.
PEG 150 Distearate is used at a concentration of 0.5% to 5% of the formulation.
PEG 150 Distearate is a solubilizer for various water-soluble ingredients.


PEG 150 Distearate also has good co-emulsifying properties in creams and lotions.
PEG 150 Distearate has been developed in recent years and has good viscosity and emulsifying properties in different types of products such as shampoos, lotions, hair conditioners, handwashing liquids, moisturizers and etc.


Ethoxylated esters have wide variety of applications including dissolvent, providing lipids needed for skin, moisturizers in cosmetic formulations such as facewash detergents, cosmetic cleansers and etc.
PEG-150 Distearate or Polyethylene glycol diester of stearic acid is an effective thickener for surfactant-containing products (e.g. shampoo, conditioner, shower gels), solubilizer for various water-insoluble ingredients, and it has good co-emulsifying properties in creams & lotions.


PEG 150 Distearate is used in shampoo, conditioner, shower gels, baby shampoo, bubble bath, creams, lotions & other emulsions.
PEG 150 Distearate is a cosmetic chemical used in cleansing products, personal care products, etc.
PEG 150 Distearate acts as an emollient as well as a viscosity modifier.


The properties of PEG 150 Distearateinclude being an effective emulsifier and thickening agent for surfactant-containing hair care products such as shampoos, and shower gels.
PEG 150 Distearate's usage can also be seen in other cosmetic applications such as baby bath products, conditioners, body creams, and lotions.
PEG 150 Distearate acts as an effective emulsifier and thickening agent for surfactant-containing hair care products such as shampoo and shower gels.


PEG 150 Distearate is used in combination with other products to make cosmetics, make up, beauty and personal care products.
Cosmetic Grade PEG 150 Stearate is used as a raw material for your cosmetic brand or DIY use to make products such as facial mask, face and body scrubs, lotions, creams, moisturizers, serums, body butters, hair and skin care and bath products, pressed powders, liquid foundation, mascara, deodorant soap, shampoo making and many more beauty and make up products


PEG-150 Distearate is used as thickener for formulas with specific detergents (liquid soaps face wash Cleanser, Shampoo, Conditioner)
PEG 150 Distearate is used for adding viscosity (thickener) to liquid soap face wash cleanser shampoo.
PEG 150 Distearate is used in beauty products and cosmetics as an emulsifier and thickening agent.
Applications of PEG 150 Distearate: Facial cleanser, shower gel, shampoo, cream, lotion and other personal care products.


PEG 150 Distearate is used in beauty products and cosmetics as an emulsifier and thickening agent.
PEG 150 Distearate is most often seen as an ingredient in shampoo and other hair products.
PEG 150 Distearate is effective thickener for surfactant-containing products (e.g. shampoo, conditioner, shower gels), solubilizer for various water-insoluble ingredients, good co-emulsifying properties in creams & lotions.


PEG 150 Distearate acts as an effective emulsifier and thickening agent for surfactant-containing hair care products such as shampoo, shower gels.
PEG 150 Distearate is also used in other cosmetics applications such as baby bath, conditioner, creams and lotions.
PEG 150 Distearate is commonly used to thicken mild, amphoteric-containing surfactant systems, such as baby shampoos, baby baths, facial scrubs, facial cleansers, body washes, body scrubs and shaving foams.


PEG 150 Distearate acts as an effective emulsifier and thickening agent for surfactant-containing hair care products.
PEG-150 Distearate is a polyethylene glycol diester of stearic acid. PEG 150 Distearate has the effect of thickening, thickening products containing cleaning agents such as transparent shampoos and shower gels.
PEG 150 Distearate is polyethylene glycol diester of stearic acid, white flakes, characteristic odor, soluble in water when heated.


The mixture is slightly turbid initially when mixed in water, or in a solution containing surfactants.
PEG 150 Distearate is particularly effective for the thickening of clear, mild, amphoteric-containing surfactant systems, such as shampoos, body washes, bubble baths, baby baths, vapor baths and shower gels.
PEG 150 Distearate can also be used to thicken facial scrubs, facial cleansers, body scrubs and shaving foams, and finds application in color cosmetics as an auxiliary emulsifer (HLB ~18.4).


The typical use level of PEG 150 Distearate is 2 – 4%.
PEG 150 Distearate is a refatting agent which could lower irritation for skin and can improve the feeling of dry and tight on skin.
On the hair conditioning, PEG 150 Distearate can provide softer feel and prevent dry hair, and reduce the electrostatic effect inter hair.
PEG 150 Distearate can provide good consistency and stability for use in bath preparations such as shampoo and shower as well as emulsion in cosmetic.


PEG 150 Distearate is in the O / W lotion and cream products also as a basis oil and fragrance solubilizers and co-emulsifiers.
PEG 150 Distearate is commonly used to thicken mild, amphoteric-containing surfactant systems, such as baby shampoos, baby baths, facial scrubs, facial cleansers, body washes, body scrubs and shaving foams.


Applications of PEG 150 Distearate: Shampoo, conditioner, shower gels, baby shampoo, bubble bath, creams, lotions & other emulsions.
PEG 150 Distearate is an efficient thickening agent for shampoos, body washes or foam baths.
Even at low levels, PEG 150 Distearate results in a high viscosity modifying effect.
PEG 150 Distearate is used in formulations which are difficult to thicken.


PEG 150 Distearate acts as an emulsifying agent (o/w) and thickener (aqueous).
PEG 150 Distearate is an ester made from the reaction of vegetable-derived triple-pressed grade stearic acid and a defined high molecular weight polyethylene glycol.
PEG 150 Distearate is commonly used to thicken mild, amphoteric-containing surfactant systems, such as baby shampoos, baby baths, facial scrubs, facial cleansers, body washes, body scrubs, shaving foams, liquid handsoaps, shower gels/body washes and color cosmetics.


PEG 150 Distearate is an effective thickener for surfactant-containing products (e.g. shampoo, conditioner, shower gels).
PEG 150 Distearate is a solubilizer for various water-insoluble ingredients.
PEG 150 Distearate has good co-emulsifying properties in creams & lotions.
PEG 150 Distearate is used as substrates or lubricants and softeners in the textile and cosmetics industry.


PEG 150 Distearate is used as dispersant in the paint industry.
PEG 150 Distearate improves the water dispersibility and flexibility of the resin, and the dosage is 20~30%.
PEG 150 Distearate can improve the solubility of dyes and reduce their volatility, especially suitable for wax paper and ink pad ink, and can also be used for ballpoint pen ink to adjust the viscosity of ink.


PEG-150 Distearate is polyethylene glycol diester of stearic acid. It is in the form of solid, white to off-white waxy flakes and used as a thickener, emulsifier, solubilizer in cosmetics and personal care products.
PEG 150 Distearate is used mainly as a thickener in products like shampoos, conditioners, shower gels, face washes, hand washes, shaving creams, baby-care products etc.


Skin care: PEG 150 Distearate is used as an emulsifier in creams and lotions
Hair care: PEG 150 Distearate is used as an anti-static agent in conditioners
Industry Primarily Used: Cosmetics, Pharmaceuticals, Inks & Coatings
PEG 150 Distearate is Hydrophilic emulsifier, and thickener.


PEG 150 Distearate is a surfactant with a high HLB (18.9).
PEG 150 Distearate is mainly used to create oil-in-water type emulsions and acts as a thickener.
PEG 150 Distearate has the effect of thickening, thickening products containing cleaning agents such as transparent shampoos and shower gels.


PEG 150 Distearate is used as dispersant in rubber industry to promote vulcanization and as dispersant of carbon black filler.
PEG 150 Distearate has a thickening effect, thickening products containing cleaning agents such as shampoos, transparent shower gels.
PEG 150 Distearate is used in beauty products and cosmetics as a surfactant and cleansing agent, and is sometimes seen as a thickening agent as well.


PEG 150 Distearate is used for its emulsifying and thickening properties in surfactant-containing hair care products such as shampoo and also shower gels.
PEG 150 Distearate is even used in other cosmetics applications such as, conditioner, creams and lotions.
In cosmetics and personal care products, PEG 150 Distearate is used in the formulation of shampoos, hair conditioners, personal cleanliness products, bath products, and skin care and skin cleansing products.


PEG 150 Distearate forms a film on the hair and reduces static and is therefore used in conditioners.
When added to paints and dyes, PEG 150 Distearate thickens their consistency and emulsifies them.
PEG 150 Distearate is also an effective thickener for transparent shampoos and personal washing preparations.
PEG 150 Distearate is used as an emulsifier for pharmaceuticals, a Thickening agent for cosmetics, an Additive for paints, Emulsifier for emulsion polymerization.


-Applications of PEG 150 Distearate:
*Shampoo, conditioner, shower gels, baby shampoo, bubble bath, creams, lotions & other emulsions.
*GSP certificate MakingCosmetics
*Organic certificate MakingCosmetics
*ICMAD membership
*Organic Trade Association membership
*ASQ Membership


-Cosmetic Uses of PEG 150 Distearate:
*surfactants
*surfactant - emulsifying
*viscosity controlling agents


-Suggested Uses of PEG 150 Distearate:
*Shampoos
*Conditioners
*Shower gels
*Baby shampoo
*Bubble bath
*Creams
*Lotions
*Other emulsions


-Applications of PEG 150 Distearate:
• Baby products such as baby shampoos
• After shave formulations
• Body washes
• Creams and lotions
• Liquid hand soaps
• “Intimate” hygiene products
• AP/DEO roll-on



BENEFITS OF PEG 150 DISTEARATE:
*Effective thickener for surfactant-containing products (e.g. shampoo, conditioner, shower gels)
*Solubilizer for various water-insoluble ingredients
*Has good co-emulsifying properties in creams & lotions



FEATURES AND BENEFITS OF PEG 150 DISTEARATE:
• Very efficient at viscosity building
• Compatible in high surfactant systems
• Salt tolerant
• Stable in acidic media
• Replacement for inorganic salts and fatty acid amines
• Excellent choice for sulfosuccinic acid ester formulations
• Soluble in glycols and surfactants
• Non-ionic
• Exhibits clear formulations
• Offers a lipid-like feel
• Imparts softening and substantive effect
• Effective over a broad pH range, from 4 to 9
• No neutralization required
• Thickener of choice for non-irritating formulations
• Helps improves foam volume and texture



WHAT DOES PEG 150 DISTEARATE DO IN A FORMULATION?
*Emulsifying
*Viscosity controlling



FUNCTIONS OF PEG 150 DISTEARATE:
1. Cleanser (Cosmetics) - Improves the cleansing properties of water
2. Emulsifier - Allows water and oils to remain mixed together to form an emulsion.
3. Surfactant - Reduces the surface tension to allow mixtures to be formed evenly.
Emulsifier is a specific type of surfactant which allows two liquids to mix together evenly
4. Effective thickener in sufactant based products.
5. Emulsifying properties in emulsion products.
6. Emulsifying agent:
Promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil)
7. Surfactant:
Reduces the surface tension of cosmetics and contributes to the even distribution of the product during use
8. Viscosity control agent:
Increases or decreases the viscosity of cosmetics



BENEFITS AND USES OF PEG 150 DISTEARATE:
*PEG 150 Distearate is used to thicken products like shampoos, conditioners, shower gels, hand washes, shaving creams, etc.
*PEG 150 Distearate is an excellent emulsifier and is usually added to creams and lotions.
*PEG 150 Distearate mixes well with water and oil and enables them to clean dirt and grime from the surface.
*PEG 150 Distearate forms a film on the hair and reduces static and is therefore used in conditioners.
*When added to paints and dyes, PEG 150 Distearate thickens their consistency and emulsifies them.



BENEFITS / APPLICATIONS OF PEG 150 DISTEARATE:
*PEG 150 Distearate is a high molecular weight distearate of
polyethyleneglycol that provides excellent properties of thickening
to formulations based on surfactants agents.
*PEG 150 Distearate is a differentiated thickener with excellent suavity.
*PEG 150 Distearate can be used in many cosmetic formulations, such as shampoos for adults, for children, foam bath, liquid soaps, etc.
*PEG 150 Distearate is a versatile product that can be used as the unique thickening agent or even associated to alkanolamides, etoxilated fatty alcohols, and betaines.
*Due to the ethylene oxide groups in its molecule, PEG 150 Distearate acts improving the viscosity of surfactants usually used in soft formulations.
Therefore, surfactants such as sorbitan monolaurate, sulfosuccinates, and betaines have its thickener profile improved.



WHAT IS THE EFFECT OF PEG 150 DISTEARATE IN HANDMADE SHOWER GEL / SHAMPOO RECIPES?
- Emulsifying aid for skin care products
- Thickener for cleaning products such as shower gel, clear shampoo



HOW TO USE PEG 150 DISTEARATE:
- Add PEG 150 Distearate to the phase containing surfactant/water
- Heat the upper beaker for PEG 150 Distearate to melt, stir well to form a gel.
PEG 150 Distearate is cloudy after stirring, let the product stand for 12-24 hours.
PEG 150 Distearate after stabilizing the foam will be transparent.



WHAT IS PEG 150 DISTEARATE USED FOR?
PEG-150 distearate is a polyethylene glycol diester of stearic acid.
PEG 150 Distearate acts as an effective emulsifier and thickening agent for surfactant-containing hair care products such as shampoo, shower gels.
PEG 150 Distearate is also used in other cosmetics applications such as baby bath, conditioner, creams and lotions.



HOW PEG 150 DISTEARATE IS CLASSIFIED:
*Texture Enhancer



PROPERTIES OF PEG 150 DISTEARATE:
PEG-150 distearate typically is supplied as solid, white to off-white waxy flakes that melt at approximately 52–57°C.
Potential impurities in the raw material can include: unreacted stearic acid or methyl stearate; monofunctional PEG 150 Distearate; unreacted PEG 150 Distearate; (trans)esterification catalyst residues; trace organic peroxides that result from oxidation of PEG; and 1,4-dioxane, a by-product of ethylene oxide poly-merization to produce PEG-150 diol.
PEG 150 Distearate distearate is water-soluble; however, it must be heated above its melting point to achieve effective dissolution and its solubility is tremendously enhanced in the presence of other surfactants.



PEG DIESTERS TYPICALLY ARE PRODUCED BY ONE OF THREE ROUTES:
1) ethoxylation of fatty acids, 2) direct esterification of PEG with fatty acids to produce water as a by-product, or 3) transesterification of fatty acid esters with PEG to produce alcohols as byproducts.
In the case of PEG-150 distearate, only Routes 2 and 3 are desirable since Route 1 leads to mixtures of mono- and difunctional PEG esters and unmodified PEG
Critical commodity feedstocks for the production of PEG-150 distearate are ethylene oxide, derived from ethylene, which is used to produce the PEG-150; and stearic acid for direct esterification, or methyl stearate for transesterification.



TECHNOLOGY AND APPLICATIONS OF PEG 150 DISTEARATE:
PEG 150 Distearate is mainly used as a micellar thickening agent for surfactant-based cleansers, especially shampoos, shower gels and face washes.
Although the exact mechanism of rheology modification by PEG 150 Distearate in surfactant solutions is not fully elucidated, it generally is accepted that PEG 150 Distearate would function similarly to other low MW telechelic hydrophobically modified polymers.

Such molecules incorporate into surfactant micelles, where they can:
increase the hydrodynamic size and viscous drag of micelles in solution by extension of hydrated PEG chains into the aqueous phase;
increase the micellar radius of curvature to promote wormlike micelle formation—due to incorporation of the bulky C18 stearate hydrophobes into the micellar core and shielding of electrostatic head group repulsions between ionic surfactants by the nonionic PEG chains; and physically crosslink micelles via intermicellar bridging.

Individually or in combination, each of these mechanisms typically leads to increases in the bulk viscosity of surfactant solutions.
Besides an increase in bulk viscosity, PEG 150 Distearate may impart other rheological effects; for example, intermicellar physical crosslinking can dramatically increase the storage modulus, i.e. elasticity, of a micellar surfactant solution.
An important specification for PEG 150 Distearate is the saponification value, a measure of the degree of esterification of the PEG ester, which is reported in mg KOH/g PEG ester.

For PEG 150 Distearate, a higher saponification value generally indicates a higher level of disubstituted PEG chains in the material, which corresponds to higher thickening efficiency.
PEG 150 Distearate has an HLB value of about 18, thus the ingredient can also be used as a nonionic emulsifier for o/w systems.
In addition, the use of PEG 150 Distearate in color cosmetics, hair conditioner and shaving preparations has been reported in the literature.

Finally, to overcome the need for the hot processing of formulas containing PEG 150 Distearate to achieve effective dissolution, as previously described, raw material suppliers also provide the ingredient in concentrated aqueous blends with common anionic, amphoteric, and/or nonionic surfactants such as sodium trideceth sulfate, cocamidopropyl betaine and PEG-80 sorbitan laurate.
Such blends simplify formulating by premixing ingredients that are commonly employed together, e.g., the amphoteric and nonionic surfactants used in baby shampoos, and enabling ambient temperature processing.



WHY IS PEG 150 DISTEARATE USED IN COSMETICS AND PERSONAL CARE PRODUCTS?
PEG Distearate ingredients clean the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away.
They also help to form emulsions by reducing the surface tension of the substances to be emulsified and help other ingredients to dissolve in a solvent in which they would not normally dissolve.



PHYSICAL and CHEMICAL PROPERTIES of PEG 150 DISTEARATE:
Boiling Point: 492-497°C
Melting Point: 52-57°C
Hydroxyl Value: 5 max.
Solubility: Soluble in water and ethanol
Insoluble in mineral and vegetable oil
Saponification Value: 165-175 mgKOH/g
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 495.30 °C. @ 760.00 mm Hg (est)
Flash Point: 513.00 °F. TCC ( 267.40 °C. ) (est)
logP (o/w): 5.997 (est)
Typical use levels: 1–5 %
Ionic nature: Non-ionic
Appearance: White ivory chips
Melting point: 54–57°C
Acid Value (mg KOH/g): Max 6
Viscosity: Brookfield @ 20°C, solubilised viscosity
at 1.6% ai (Spindle 2 @ 20 rpm, 1 min) 1000–1600 cPs



FIRST AID MEASURES of PEG 150 DISTEARATE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water.
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of PEG 150 DISTEARATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of PEG 150 DISTEARATE:
-Extinguishing media:
--Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
--Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.



EXPOSURE CONTROLS/PERSONAL PROTECTION of PEG 150 DISTEARATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Safety glasses.
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of PEG 150 DISTEARATE:
-Conditions for safe storage, including any incompatibilities:
Storage conditions:
Tightly closed.
Recommended storage temperature see product label.



STABILITY and REACTIVITY of PEG 150 DISTEARATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
no information available



SYNONYMS:
Polyethylene Glycol Distearate, Polyglycol Disearate ,
PEG 6000
Rewopa PEG 6000 DS
PEG-150 Distearate
Lipopeg 6000-DS
Triethylene Glycol Distearate
Triethylene Glycol Distearate
Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-[(1-oxooctadecyl)oxy]-
Macrogol 6000
Polyethylenglycol 6000
Polyethylenglykol 6000 Distearat
Polyoxyethylen(150)
Polyoxyethylen(150)distearat
PEG-150 Distearate
PEG-3 Distearate
PEG-32 Distearate
PEG-6 Distearate
PEG-75 Distearate
Polyethylene glycol (3) distearate
Polyethylene glycol 1540 distearate
Polyethylene glycol 300 distearate
Polyethylene glycol 4000 distearate
Polyethylene glycol 600 distearate
Polyethylene glycol 6000 distearate
Polyoxyethylene (12) distearate
Polyoxyethylene (150) distearate
Polyoxyethylene (3) distearate
Polyoxyethylene (32) distearate
Polyoxyethylene (6) distearate
Polyoxyethylene (75) distearate
Triglycol distearate
Carbowax 1000 distearate
Emerest 2642
Lipal 15-DS
Nonex 80
PEG 1540 distearate
Polyethylene glycol 400 (di) stearate
Polyethylene glycol 600 (di) stearate
Polyethylene glycol distearate
Polyglycol distearate
S 1009
S 1013
Stabogel
Stearic acid, polyethylene glycol diester
Poly(oxy-1,2-ethanediyl), alpha-(1-oxooctadecyl)-omega-((1-oxooctadecyl)oxy)-
Polyethylene glycol distearate #1000
Polyoxyethylene distearate
Lipopeg 4-DS
PEG-8 Distearate
poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-[(1-oxooctadecyl)oxy]- (150 mol EO average molar ratio)
Polyethylene Glycol Distearate
Polyglycol Disearate

PEG 1500 Properties of PEG 1500 Related Categories Essential Chemicals, Poly(ethylene glycol) (PEG) and PEG Solutions, Research Essentials Less... form solution mol wt of PEG 1500 Mr ~1500 packaging of PEG 1500 pkg of 10 × 4 mL mfr. no. Roche shipped in wet ice storage temp. 2-8°C SMILES string C(CO)O Show More (10) Description of PEG 1500 General description of PEG 1500 Poly(ethylene glycol) ( PEG 1500) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG also interacts with cell membrane, thereby allowing cell fusion.[4][5] Application of PEG 1500 Polyethylene Glycol 1500 (PEG 1500) has been used to mediate cell fusion.[1][2][3] Physical form of PEG 1500 Solution, filtered through 0.2 μm pore size membrane, 50% PEG 1500 (w/v) in 75 mM Hepes (pH 8.0), bottled under nitrogen, ready to use Other Notes of PEG 1500 For life science research only. Not for use in diagnostic procedures. Product name : Polyglycol PEG 1500 Grade of PEG 1500 : Extra pure Synonym of PEG 1500 : Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 1500 Formula of PEG 1500 : HO(C₂H₄O)nH Description of PEG 1500 Cas no of PEG 1500 : 25322-68-3 EC no. of PEG 1500 : 500-038-2 Product Description of PEG 1500 Application field of PEG 1500: Pharmacology and Cosmetics production (as base for creams, toothpastes and lipsticks) Detergent & Household goods production (as soap bars glue, soluble agent in detergent pastes, fixing agent for odors in soaps and detergents, as additive in general cleaners, polishers, air fresheners, automatic dishwashing detergents) Production of textile supporting substances (component of dispergators and protective solutions) Rubber goods production (non adhesive agent for forms treatment) Metal works industry (agent for cleaning and polishing pastes, lubricating & cooling liquids). Polyethylene glycol PEG 1500 Polyethylene glycol (PEG; /ˌpɒliˈɛθəlˌiːn ˈɡlaɪˌkɒl, -ˌkɔːl/) is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine. PEG 1500 is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight. The structure of PEG 1500 is commonly expressed as H−(O−CH2−CH2)n−OH.[3] Uses of PEG 1500 Medical uses Main articles: Macrogol and PEGylation PEG is the basis of a number of laxatives.[4] Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy. PEG 1500 is also used as an excipient in many pharmaceutical products. When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood.[5] The possibility that PEG could be used to fuse axons is being explored by researchers studying peripheral nerve and spinal cord injury.[4] An example of PEG hydrogels (see "Biological uses" section) in a therapeutic has been theorized by Ma et al. They propose using the hydrogel to address periodontitis (gum disease) by encapsulating stem cells in the gel that promote healing in the gums.[6] The gel and encapsulated stem cells was to be injected to the site of disease and crosslinked to create the microenvironment required for the stem cells to function. A PEGylated lipid is used as an excipient in both the Moderna and Pfizer–BioNTech vaccines for SARS-CoV-2. Both RNA vaccines consist of Messenger RNA, or mRNA, encased in a bubble of oily molecules called lipids. Proprietary lipid technology is used for each. In both vaccines, the bubbles are coated with a stabilizing molecule of polyethylene glycol.[medical citation needed] As of December 2020 there is some concern that PEG could trigger allergic reaction,[7] and in fact allergic reactions are the driver for both the UK and Canadian regulators to issue an advisory, noting that: two individuals "individuals in the U.K... were treated and have recovered" from anaphylactic shock.[8][9] As of 18 December, the US CDC stated that in their jurisdiction six cases of "severe allergic reaction" had been recorded from more than 250,000 vaccinations, and of those six only one person had a "history of vaccination reactions".[10] Chemical uses The remains of the 16th century carrack Mary Rose undergoing conservation treatment with PEG in the 1980s Terra cotta warrior, showing traces of original color Because PEG is a hydrophilic molecule, it has been used to passivate microscope glass slides for avoiding non-specific sticking of proteins in single-molecule fluorescence studies.[11] Polyethylene glycol has a low toxicity and is used in a variety of products.[12] The polymer is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments.[13] Since PEG is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures (on the order of tens of atmospheres). It also is unlikely to have specific interactions with biological chemicals. These properties make PEG one of the most useful molecules for applying osmotic pressure in biochemistry and biomembranes experiments, in particular when using the osmotic stress technique. Polyethylene glycol is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers. PEG has also been used to preserve objects that have been salvaged from underwater, as was the case with the warship Vasa in Stockholm,[14] and similar cases. It replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.[4] In addition, PEG is used when working with green wood as a stabilizer, and to prevent shrinkage.[15] PEG has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China.[16] These painted artifacts were created during the Qin Shi Huang (first emperor of China) era. Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xi'an air. The paint would subsequently flake off in about four minutes. The German Bavarian State Conservation Office developed a PEG preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.[17] PEG is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning. PEG 1500 derivatives, such as narrow range ethoxylates, are used as surfactants. PEG 1500 has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.[18] PEG 1500 has also been used as a propellent on the UGM-133M Trident II Missile, in service with the United States Air Force.[19] Biological uses of PEG 1500 PEG can be modified and crosslinked into a hydrogel and used to mimic the extracellular matrix (ECM) environment for cell encapsulation and studies.[20][21] An example study was done using PEG-Diacrylate hydrogels to recreate vascular environments with the encapsulation of endothelial cells and macrophages. This model furthered vascular disease modeling and isolated macrophage phenotype's effect on blood vessels.[22] PEG is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.[11] PEG is commonly used as a precipitant for plasmid DNA isolation and protein crystallization. X-ray diffraction of protein crystals can reveal the atomic structure of the proteins. PEG is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas. César Milstein and Georges J. F. Köhler originated this technique, which they used for antibody production, winning a Nobel Prize in Physiology or Medicine in 1984.[4] Polymer segments derived from PEG polyols impart flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam cushions. In microbiology, PEG precipitation is used to concentrate viruses. PEG is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro. Gene therapy vectors (such as viruses) can be PEG-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect.[23] The size of the PEG polymer has been shown to be important, with larger polymers achieving the best immune protection. PEG is a component of stable nucleic acid lipid particles (SNALPs) used to package siRNA for use in vivo.[24][25] In blood banking, PEG is used as a potentiator to enhance detection of antigens and antibodies.[4][26] When working with phenol in a laboratory situation, PEG 300 can be used on phenol skin burns to deactivate any residual phenol (some references are required). In biophysics, polyethylene glycols are the molecules of choice for the functioning ion channels diameter studies, because in aqueous solutions they have a spherical shape and can block ion channel conductance.[27][28] Commercial uses PEG is the basis of many skin creams (as cetomacrogol) and personal lubricants (frequently combined with glycerin). PEG is used in a number of toothpastes[4] as a dispersant. In this application, it binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste. PEG is also under investigation for use in body armor, and in tattoos to monitor diabetes.[29][30] In low-molecular-weight formulations (e.g. PEG 400), it is used in Hewlett-Packard designjet printers as an ink solvent and lubricant for the print heads. PEG is also used as an anti-foaming agent in food and drinks[31] – its INS number is 1521[32] or E1521 in the EU.[33] Industrial uses A nitrate ester-plasticized polyethylene glycol (NEPE-75) is used in Trident II submarine-launched ballistic missile solid rocket fuel.[34] Dimethyl ethers of PEG are the key ingredient of Selexol, a solvent used by coal-burning, integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the gas waste stream. PEG has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.[35] PEG is also used as a polymer host for solid polymer electrolytes. Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving PEG, with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future. PEG is injected into industrial processes to reduce foaming in separation equipment. PEG is used as a binder in the preparation of technical ceramics.[36] Recreational uses PEG is used to extend the size and durability of very large soap bubbles. PEG is the main ingredient in many personal lubricants. (Not to be confused with propylene glycol.) Health effects PEG is considered biologically inert and safe by the FDA. However, a growing body of evidence shows the existence of a detectable level of anti-PEG antibodies in approximately 72% of the population, never treated with PEGylated drugs, based on plasma samples from 1990–1999.[37] The FDA has been asked to investigate the possible effects of PEG in laxatives for children. Since 1999, the FDA has received over 1,000 incident reports from parents reporting serious or life threatening side effects after their children were given one or more doses of PEG as an osmotic laxative.[38] Miralax has not been tested on children. PEG is not recommended to those under 18. Due to its ubiquity in a multitude of products and the large percentage of the population with antibodies to PEG, hypersensitive reactions to PEG are an increasing concern.[39][40] Allergy to PEG is usually discovered after a person has been diagnosed with an allergy to an increasing number of seemingly unrelated products, including processed foods, cosmetics, drugs, and other substances that contain PEG or were manufactured with PEG.[39] When PEG is chemically attached to therapeutic molecules (such as protein drugs or nanoparticles), it can sometimes be antigenic (a molecule which stimulates an immune response), stimulating an anti-PEG antibody response in some patients. This effect has only been shown for a few of the many available PEGylated therapeutics, but it has significant effects on clinical outcomes of affected patients.[41] Other than these few instances where patients have anti-PEG immune responses, it is generally considered to be a safe component of drug formulations.[medical citation needed] Available forms and nomenclature PEG, PEO, and POE refer to an oligomer or polymer of ethylene oxide. The three names are chemically synonymous, but historically PEG is preferred in the biomedical field, whereas PEO is more prevalent in the field of polymer chemistry. Because different applications require different polymer chain lengths, PEG has tended to refer to oligomers and polymers with a molecular mass below 20,000 g/mol, PEO to polymers with a molecular mass above 20,000 g/mol, and POE to a polymer of any molecular mass.[42] PEGs are prepared by polymerization of ethylene oxide and are commercially available over a wide range of molecular weights from 300 g/mol to 10,000,000 g/mol.[43] PEG and PEO are liquids or low-melting solids, depending on their molecular weights. While PEG and PEO with different molecular weights find use in different applications, and have different physical properties (e.g. viscosity) due to chain length effects, their chemical properties are nearly identical. Different forms of PEG are also available, depending on the initiator used for the polymerization process – the most common initiator is a monofunctional methyl ether PEG, or methoxypoly(ethylene glycol), abbreviated mPEG. Lower-molecular-weight PEGs are also available as purer oligomers, referred to as monodisperse, uniform, or discrete. Very high-purity PEG has recently been shown to be crystalline, allowing determination of a crystal structure by x-ray crystallography.[43] Since purification and separation of pure oligomers is difficult, the price for this type of quality is often 10–1000 fold that of polydisperse PEG. PEGs are also available with different geometries. Branched PEGs have three to ten PEG chains emanating from a central core group. Star PEGs have 10 to 100 PEG chains emanating from a central core group. Comb PEGs have multiple PEG chains normally grafted onto a polymer backbone. The numbers that are often included in the names of PEGs indicate their average molecular weights (e.g. a PEG with n = 9 would have an average molecular weight of approximately 400 daltons, and would be labeled PEG 400.) Most PEGs include molecules with a distribution of molecular weights (i.e. they are polydisperse). The size distribution can be characterized statistically by its weight average molecular weight (Mw) and its number average molecular weight (Mn), the ratio of which is called the polydispersity index (ĐM). Mw and Mn can be measured by mass spectrometry. PEGylation is the act of covalently coupling a PEG structure to another larger molecule, for example, a therapeutic protein, which is then referred to as a PEGylated protein. PEGylated interferon alfa-2a or −2b are commonly used injectable treatments for hepatitis C infection. PEG is soluble in water, methanol, ethanol, acetonitrile, benzene, and dichloromethane, and is insoluble in diethyl ether and hexane. It is coupled to hydrophobic molecules to produce non-ionic surfactants.[44] PEGs potentially contain toxic impurities, such as ethylene oxide and 1,4-dioxane.[45] Ethylene Glycol and its ethers are nephrotoxic if applied to damaged skin.[46] Polyethylene oxide (PEO, Mw 4 kDa) nanometric crystallites (4 nm) PEG and related polymers (PEG phospholipid constructs) are often sonicated when used in biomedical applications. However, as reported by Murali et al., PEG is very sensitive to sonolytic degradation and PEG degradation products can be toxic to mammalian cells. It is, thus, imperative to assess potential PEG degradation to ensure that the final material does not contain undocumented contaminants that can introduce artifacts into experimental results.[47] PEGs and methoxypolyethylene glycols are manufactured by Dow Chemical under the trade name Carbowax for industrial use, and Carbowax Sentry for food and pharmaceutical use. They vary in consistency from liquid to solid, depending on the molecular weight, as indicated by a number following the name. They are used commercially in numerous applications, including foods, in cosmetics, in pharmaceutics, in biomedicine, as dispersing agents, as solvents, in ointments, in suppository bases, as tablet excipients, and as laxatives. Some specific groups are lauromacrogols, nonoxynols, octoxynols, and poloxamers. Macrogol, MiraLax, GoLytely, Colace used as a laxative, is a form of polyethylene glycol. The name may be followed by a number which represents the average molecular weight (e.g. macrogol 3350, macrogol 4000 or macrogol 6000). Production Polyethylene glycol 400, pharmaceutical quality Polyethylene glycol 4000, pharmaceutical quality The production of polyethylene glycol was first reported in 1859. Both A. V. Lourenço and Charles Adolphe Wurtz independently isolated products that were polyethylene glycols.[48] Polyethylene glycol is produced by the interaction of ethylene oxide with water, ethylene glycol, or ethylene glycol oligomers.[49] The reaction is catalyzed by acidic or basic catalysts. Ethylene glycol and its oligomers are preferable as a starting material instead of water, because they allow the creation of polymers with a low polydispersity (narrow molecular weight distribution). Polymer chain length depends on the ratio of reactants. HOCH2CH2OH + n(CH2CH2O) → HO(CH2CH2O)n+1H Depending on the catalyst type, the mechanism of polymerization can be cationic or anionic. The anionic mechanism is preferable because it allows one to obtain PEG with a low polydispersity. Polymerization of ethylene oxide is an exothermic process. Overheating or contaminating ethylene oxide with catalysts such as alkalis or metal oxides can lead to runaway polymerization, which can end in an explosion after a few hours. Polyethylene oxide, or high-molecular weight polyethylene glycol, is synthesized by suspension polymerization. It is necessary to hold the growing polymer chain in solution in the course of the polycondensation process. The reaction is catalyzed by magnesium-, aluminium-, or calcium-organoelement compounds. To prevent coagulation of polymer chains from solution, chelating additives such as dimethylglyoxime are used. Alkaline catalysts such as sodium hydroxide (NaOH), potassium hydroxide (KOH), or sodium carbonate (Na2CO3) are used to prepare low-molecular-weight polyethylene glycol.

DESCRIPTION:
PEG 20 METHYL GLUCOSE ETHER is a polyethylene glycol ether of the mono anddiesters of methyl glucose and stearic acid with an average of 20 moles of ethylene oxide.

A mild, water-loving emulsifier that's safe for sensitive skin or eye-care formulations.
PEG 20 METHYL GLUCOSE ETHER helps to create low viscosity oil-in-water emulsions, ideal for milks, serums, and sprayable formulations.

CAS Number: 68389-70-8
European Community (EC) Number 615-727-4
Chem/IUPAC Name: Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, ether with methyl .beta.-d-glucopyranoside (4:1), octadecanoate (2:3) (20 mol EO average molar ratio)
Molecular Formula C27H54O9



CHEMICAL AND PHYSICAL PROPERTIES OF PEG 20 METHYL GLUCOSE ETHER:
Molecular Weight 522.7
Hydrogen Bond Donor Count 5
Hydrogen Bond Acceptor Count 9
Rotatable Bond Count 21
Exact Mass 522.37678330
Monoisotopic Mass 522.37678330
Topological Polar Surface Area 146 Ų
Heavy Atom Count 36
Formal Charge 0
Complexity 478
Isotope Atom Count 0
Defined Atom Stereocenter Count 4
Undefined Atom Stereocenter Count 1
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

It's derived from natural sources and gives a light, satiny after feel

USE & BENEFITS OF PEG 20 METHYL GLUCOSE ETHER :
PEG 20 METHYL GLUCOSE ETHER is used for its emulsifying properties in cosmetic products.
As an emulsifier, PEG 20 METHYL GLUCOSE ETHER gives stability to the product and prevents the oil and water-based components of the product from getting separated.
Since molecules dissolving in water can take up the PEG part and oil dissolving molecules will get attached to the stearate part.

So, PEG 20 METHYL GLUCOSE ETHER reduces a chance of inter-reaction of various ingredients and gives noticeable stability to the product.
PEG 20 METHYL GLUCOSE ETHER also functions as a thickener by attracting water molecules and gives a sort of ‘swollen’ appearance to its molecule.
PEG 20 METHYL GLUCOSE ETHER enhances its overall performance of the product on the skin or hair surface.

A watery or less thick formulation may not feel appealing to customer and it may not show promising performance as well.
PEG 20 METHYL GLUCOSE ETHER is used in formulations of creams, lotions, gels, shampoos, and other skincare products.




SAFETY INFORMATION ABOUT PEG 20 METHYL GLUCOSE ETHER:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.





SYNONYMS OF PEG 20 METHYL GLUCOSE ETHER
Depositor-Supplied Synonyms:
72175-39-4
PEG-20 methyl glucose sesquistearate
18-[(2R,3S,4R,5R)-4,5-dihydroxy-2-(hydroxymethyl)-6-methoxyoxan-3-yl]oxyoctadecanoic acid;ethanol
UNII-0345752X7U
DTXSID60992896
0345752X7U
Methyl 4-O-(17-carboxyheptadecyl)hexopyranoside--ethanol (1/1)

PEG-200, polyethylene glycol (200-600) , CAS : 25322-68-3. Synonymes : polyethylene glycol (200-600);PEG;Polymère d'oxyéthylène;Poly(oxy-1,2-éthynediyl), alpha-hydro-oméga-hydroxy;Oxyethylene polymer.N° CAS : 25322-68-3. Origine(s) : Synthétique.Nom INCI : PEG-200. Additif alimentaire : E1521. Classification : PEG/PPG, Composé éthoxylé, Glycol, Polymère de synthèse. Ses fonctions (INCI). Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau. Solvant : Dissout d'autres substances

Peg 200 stearate is the polyethylene glycol ester of stearic acid.
Peg 200 stearate is a nonionic mild fatty acid ester used primarily as a surfactant.
Peg 200 stearate also imparts better spreading characteristics to creams and lotions and can be used as an emulsifier, lubricating agent and dispersant.

CAS Number: 9004-99-3
Molecular Formula: C34H70O9
Molecular Weight: 622.91
EINECS Number: 618-405-1

Peg-200 stearate, N93S2IJC6C,MYRJ(TM) 53,MYRJ(TM) 59,MYRJ 58,MYRJ 59,MYRJ(R) 53,MYRJ(TM) 45,MYRJ 45,PEG 200 STEARATE

Peg 200 stearate is a mixture of the monoand diesters of stearic acid and mixed polyoxyethylene diols having an average polymer length of 7.5 oxyethylene units.
Peg 200 stearate is a polymer with the chemical formula HO(CH2CH2O)nH. Its properties vary according to its molecular weight, from a colourless and odourless viscous liquid to a waxy solid.
Peg 200 stearate is a liquid at room temperature with a molecular weight of 200 to 600, and gradually becomes a semi-solid with a molecular weight above 600, with different properties depending on the average molecular weight.

From colourless and odourless viscous liquids to waxy solids.
As the molecular weight increases, its hygroscopic capacity decreases accordingly.
Peg 200 stearate is soluble in water, ethanol and many other organic solvents.

Peg 200 stearate has a low vapour pressure and is stable to heat, acids and bases.
Peg 200 stearate does not interact with many chemicals. It has good hygroscopicity, lubricity and bonding properties.
Peg 200 stearate is white granular.

Soluble in water, soluble in some organic solvents.
Peg 200 stearate is solution has high viscosity at low concentration, and can be processed by calendering, extrusion, casting, etc.
Peg 200 stearate is a thermoplastic resin with good compatibility with other resins.

Peg 200 stearate is resistant to bacterial erosion and has weak hygroscopicity in the atmosphere.
Peg 200 stearate is a polyethylene glycol (PEG) derivative of stearic acid.
Peg 200 stearates are a family of compounds that are formed by polymerizing ethylene oxide, and they are often used in the cosmetic and pharmaceutical industries as emollients, emulsifiers, and solubilizing agents.

Peg 200 stearate is a saturated fatty acid found in various animal and vegetable fats.
When combined with polyethylene glycol to form PEG-200 Stearate, it serves as an emulsifying agent.
Emulsifiers help stabilize and maintain the consistency of mixtures containing both water and oil components.

In cosmetics, Peg 200 stearate may be used in creams, lotions, and other skincare products to improve texture, stability, and the overall performance of the formulation.
Peg 200 stearate is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine.
Peg 200 stearate is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight.

The structure of PEG is commonly expressed as H−(O−CH2−CH2)n−OH.
Peg 200 stearate serve as consistency enhancers in lipsticks and creams as well as humectants.
They are well tolerated by the skin and are not microbiologically sensitive, so that in general it is not necessary to add any preservatives.

Peg 200 stearates are poly condensation products of ethylene glycol, or polymerisation products of ethylene oxide.
The number added to the name refers to the mean number of ethylene oxide units in the Peg 200 stearate.
The consistency of the PEG derivatives is increasingly solid with a growing degree of polymerisation.

Peg 200 stearates with a mean molar mass of up to 600 g/mol are liquid, up to 1,000 g/mol wax-like and from 4,000 g/mol solid wax-like substances.
By mixing solid and liquid components, products of a creamy consistency are obtained which are used as water-free and water rinse-off bases.
With growing molar mass water solubility and hygroscopicity (ability to absorb moisture) of the polyethylene glycols decrease.

Peg 200 stearates and their derivates are preferentially used in cosmetic products since they have a broad spectrum of viscosity and solubility properties and have a very good skin tolerance.
As water soluble, non-greasy substances polyethylene glycols are suitable for many cosmetic purposes.
The liquid Peg 200 stearates serve, eg, as glycerol substitute in facial, shaving and hair lotions, as solubilisers and solvents.

Having immense market shares in the market, fulfill the wide requirements of patrons by providing top quality Peg 200 stearate Mono And Di Stearates. The offered product is processed using quality tested compounds with the help of latest methodology under the observation of deft professionals.
Provided product is used an emulsifier and water treatment industry viscosity controllers and processing aid in textile industry.
Apart from this, the offered Peg 200 stearate can be availed from us at competitive prices by our valuable clients.

Peg 200 stearate Market size is expected to develop revenue and exponential market growth at a remarkable CAGR during the forecast period from 2023–2030.
The growth of the market can be attributed to the increasing demand for Peg 200 stearate owning to the Cosmetic, Skin Care Products, Hair Care Products, Other Applications across the global level.
The report provides insights regarding the lucrative opportunities in the Peg 200 stearate at the country level.

The report also includes a precise cost, segments, trends, region, and commercial development of the major key players globally for the projected period.
Peg 200 stearate report represents gathered information about a market within an industry or various industries. The PEG-200 Glyceryl Stearate Market report includes analysis in terms of both quantitative and qualitative data with a forecast period of the report extending from 2023 to 2030.
The report is prepared to take into consideration various factors such as Product pricing, Product or services penetration at both country and regional levels, Country GDP, market dynamics of parent market & child markets, End application industries, major players, consumer buying behavior, economic, political, social scenarios of countries, many others.

The report is divided into various segments to offer a detailed analysis of the market from every possible aspect of the market.
The overall report focuses on primary sections such as – market segments, market outlook, competitive landscape, and company profiles.
The segments provide details in terms of various perspectives such as end-use industry, product or service type, and any other relevant segmentation as per the market’s current scenario which includes various aspects to perform further marketing activity.

The market outlook section gives a detailed analysis of market evolution, growth drivers, restraints, opportunities, and challenges, Porter’s 5 Force’s Framework, macroeconomic analysis, value chain analysis and pricing analysis that directly shape the market at present and over the forecasted period.
The drivers and restraints cover the internal factors of the market whereas opportunities and challenges are the external factors that are affecting the market.
The market outlook section also gives an indication of the trends influencing new business development and investment opportunities.

Peg 200 stearate is listed as particularly applicable for hand and body lotions and creams.
Peg 200 stearate is an emulsifier.
Peg 200 stearate is part of a family of PEG-stearate compounds, with the number indicating the average molecular weight of the polyethylene glycol chain.

In this case, Peg 200 stearate has a polyethylene glycol chain with an average molecular weight of 200.
The stearate portion of the molecule is derived from stearic acid, a long-chain fatty acid.
Peg 200 stearate is primary function is as an emulsifying agent, helping to stabilize and blend water and oil-based ingredients in formulations.

This is particularly important in cosmetic and pharmaceutical products where a consistent texture and appearance are desired.
Peg 200 stearate can contribute to the smoothness and spreadability of a product.
Peg 200 stearate helps improve the overall sensory experience of applying creams and lotions.

Due to its emulsifying properties, products containing Peg 200 stearate may enhance hydration by combining water and oil components effectively.
This is beneficial for moisturizing and hydrating formulations.
Peg 200 stearate is often compatible with a wide range of cosmetic and personal care ingredients, making it versatile for use in various formulations.

Peg 200 stearate can also be found in some cleansing products, contributing to the formulation's ability to remove dirt and oil from the skin.
Peg 200 stearate is an emulsifier and antifoaming agent used in processed foods, fruit jellies, and sauces.
Peg 200 stearate has been used in a study to assess the phase behaviors of special hot microemulsion to produce drug-loaded nanostructured lipid carriers.

Peg 200 stearate has also been used in a study to investigate its effects on multidrug resistance.
Peg 200 stearate compounds are produced through a process called ethoxylation, which involves reacting ethylene oxide with a precursor compound.
The extent of ethoxylation determines the length of the Peg 200 stearate chain.

Manufacturers take steps to ensure that ethoxylation is carried out under controlled conditions to produce safe and effective ingredients.
Peg 200 stearate is used globally in a wide range of personal care and cosmetic products.
Peg 200 stearate is acceptance and use are driven by its functional properties and its ability to enhance the performance of various formulations.

Peg 200 stearate is used in cosmetics and beauty products primarily as a surfactant and emulsifier.
Peg 200 stearate occurs naturally as a white, waxy or flaky substance.
Peg 200 stearate is an emulsifier.

Melting point: 47 °C
Flash point: 39 °C
storage temp.: 2-8°C
Water Solubility: Soluble in water
solubility: Chloroform (Slighty), Methanol (Slightly)
form: powder to lump
color: White to Almost white
Odor: at 100.00?%. mild fatty
Hydrophilic-Lipophilic Balance (HLB): 18.8
LogP: 7.629 (est)

Peg 200 stearate, like other PEG derivatives, has a specific HLB value.
This value determines the balance between its hydrophilic (water-attracting) and lipophilic (oil-attracting) properties.
The Peg 200 stearate value is crucial for formulators when selecting emulsifiers to achieve the desired characteristics in a product.

In formulations, Peg 200 stearate is sometimes used in combination with other emulsifiers to optimize stability and achieve specific texture and performance goals.
Blending different emulsifiers allows formulators to fine-tune the properties of a product.
Peg 200 stearate Stearate can contribute to the viscosity or thickness of a product.

This can be advantageous in creating creams and lotions with a desirable consistency for easy application and spreadability.
In some formulations, Peg 200 stearate may play a role in enhancing the absorption or penetration of other active ingredients into the skin.
This property is important in skincare products where effective delivery of active compounds is desired.

During the manufacturing process, attention is given to controlling the molecular weight and purity of Peg 200 stearate to meet quality standards.
This includes measures to minimize impurities that could potentially be present, such as 1,4-dioxane.
Peg 200 stearates enables a significant reduction of the active surfactant level in standard cleansing formulations.

In addition, the extraordinary efficiency and high flexibility of Peg 200 stearate facilitate the thickening of challenging surfactant systems, such as sulfate-free formulas, effectively supporting the trend for milder cleansing in personal care.
The 100% active, preservative-free solid is clearly soluble in water and processable at room temperature.
Peg 200 stearate is a non-ionic surfactant, which is permitted for use as the E number food additive E431.

Peg 200 stearate is a mixture of polyethylene glycol esters.
Peg 200 stearate is compatible with lipophilic compounds due to a higher free fatty acid content.
Suggested applications: cosmetic formulations, lubricants.

Peg 200 stearate is a high molecular weight, high HLB surface active agent suggested for use in cosmetic formulations (emulsifier, viscosity modifier) and in lubricants (emulsifier).
The larger the surfactantn of Peg 200 stearate is a neutral, the lower the saponification value (mgKOH/g) and the larger the HLB value.
The pH of 1% aqueous solution is between 5.0 and 7.5, in which n≤ 8 is diffusive in water and has good flexibility and lubricity.

Peg 200 stearate can be used as a softener for fiber processing and has good antistatic and lubricity.
Peg 200 stearate is use softener during fabric weaving to reduce breakage and improve fabric feel.
As an emulsifier in cosmetics, the general dosage is 1-3%.

Peg 200 stearate can also be used as a co-emulsifier for the emulsification of paraffin wax.
Peg 200 stearate is used as emulsifier in lubricating oil production.
When 9 ≤n≤ 11, Peg 200 stearate diffuses in water and has good emulsification and cleaning efficiency.

Peg 200 stearate is used as emulsifier in cosmetics, ointment, paste shoe polish and other products, and has thickening effect.
In the textile industry, emulsifiers and oils used in synthetic fiber finishing are flexible and antistatic.
Peg 200 stearate is used as thickener and stabilizer in paper starch coating.

Lubricant used for multiplex transmission wires in cable ducts.
When 12 ≤ n≤ 25, Peg 200 stearate is soluble in a variety of solvents such as ethanol, and the water is dispersed, which is stable to a variety of electrolytes and has good emulsification, softness and antistatic properties.
Peg 200 stearate is used as softener and antistatic agent in textile industry, emulsifier and solubilizer in cosmetics, food and pharmaceutical industry, and can also be used for emulsification of cardboard, construction board and waterproof wax. 40 ≤n≤ 100, soluble in water, ethanol, carbon tetrachloride, etc., with good emulsification, wetting, complexation and thickening properties.

As an emulsifier, solubilizer, ointment matrix in the pharmaceutical industry, as an emulsifier and detergent in the cosmetics industry, as a softener and antistatic agent in the textile industry, and as an emulsifying additive in the food industry.
Peg 200 stearate is a neutral surfactant.
Peg 200 stearate is commonly used in a variety of cosmetic and personal care products, including creams, lotions, sunscreens, and other skincare formulations.

Peg 200 stearate is versatility and ability to improve the stability of emulsions make it a popular choice for formulators.
Emulsions that contain PEG-200 Stearate tend to have improved stability over time.
This stability is crucial for maintaining the integrity of the product and preventing phase separation (separation of water and oil phases).

Peg 200 stearate acts as a surfactant, which means it can reduce the surface tension between different phases in a formulation.
This property is valuable in achieving a homogenous blend of ingredients.
Peg 200 stearate can enhance the solubility of certain ingredients in formulations.

This can be particularly useful in creating products with a diverse range of components.
Peg 200 stearate itself is generally regarded as safe for use in cosmetics, the overall safety of a product also depends on the specific formulation and the concentration of ingredients.
Regulatory bodies in different countries, such as the U.S. Food and Drug Administration (FDA) and the European Commission, set guidelines for the use of cosmetic ingredients to ensure product safety.

Peg 200 stearate is considered safe for use in cosmetics, individuals with very sensitive skin may want to be cautious and patch-test products containing this ingredient, as with any new skincare or cosmetic product.
Peg 200 stearates are known for their biodegradability, which is a positive environmental characteristic.
However, the overall environmental impact of a product depends on its complete formulation, including other ingredients and packaging.

Peg 200 stearate has been recommended as an additive to the radiolabelled 7H12 Middlebrook TB media and as such has been shown to enhance growth of mycobacteria in the radiometric BACTEC rapid culture system.
Peg 200 stearate produces the greatest enhancement in growth and reduction in the time taken to detect growth for M. tuberculosis and polyoxyethylene (30) stearate and polyoxyethylene (JL) stearate for species of mycobacteria other than M. tuberculosis.
Peg 200 stearate inhibits P-gp mediated efflux in a concentration dependent manner mainly by modulating substrate-stimulated P-gp ATPase activity.

Peg 200 stearate reduces vinblastine sulfate efllux.
The cytotoxicity of vinblastine to K562/ADR cells is significantly enhanced when the cells are cotreated with 100 or 150 μg/mL Peg 200 stearate.
Peg 200 stearate is a neutral surfactant.

Peg 200 stearate is a non-ionic surfactant, which is permitted for use as the E number food additive E431.
Peg 200 stearate is an octadecanoate ester composed of repeating 8-40 ethyleneoxy units.
Peg 200 stearate is an ingredient used in cosmetics.

Peg 200 stearate is an ingredient used in beauty products primarily as a surfactant and emulsifier.
Peg 200 stearate is a mixture of the monoand diesters of stearic acid.
Peg 200 stearate is mixed polyoxyethylene diols having an average polymer length of 7.5 oxyethylene units.

Uses:
Peg 200 stearate is an emulsifier and antifoaming agent used in processed foods, fruit jellies, and sauces.
Peg 200 stearate is compatible with lipophilic compounds due to a higher free fatty acid content.
Suggested applications: cosmetic formulations, lubricants.

Peg 200 stearate is listed as particularly applicable for hand and body lotions and creams.
Peg 200 stearate can be used as a medium for organic synthesis and a heat carrier with high requirements.
Peg 200 stearate is used as a humectant, inorganic salt solubilizer and viscosity adjuster in the daily chemical industry; as a softener and antistatic agent in the textile industry; as a wetting agent in the paper and pesticide industry.

Peg 200 stearate is most suitable for softgels.
Peg 200 stearate is a liquid, it has a wide range of compatibility with various solvents and is a good solvent and solubiliser, and is widely used in liquid formulations, such as oral liquids and eye drops.
Peg 200 stearate is the material of choice when vegetable oils are not suitable as a carrier for active ingredients.

Peg 200 stearate is used as a base or lubricant and softener in the pharmaceutical, textile and cosmetic industries; used as a dispersant in the paint industry to improve the water dispersibility and flexibility of resins, with a dosage of 10-30%; used to improve the solubility of dyestuffs and reduce their volatility in printing ink, especially in wax paper and printing ink, also used to adjust the consistency of ink in biros ink.
Peg 200 stearate is also used as a dispersant in the rubber industry to promote vulcanisation and as a dispersant for carbon black filling materials.

Peg 200 stearate is used as metal processing casting agent, lubricant and cutting fluid for metal drawing, stamping or forming, grinding cooling lubricating polishing agent, welding agent, etc.; used as lubricant in paper industry, etc., also used as hot melt adhesive to increase fast rewetting ability.
Peg 200 stearate good coating material, hydrophilic polishing material, film and capsule material, plasticizer, lubricant and drip matrix for the preparation of tablets, pills, capsules, microcapsules, etc.
Peg 200 stearate is used as a finishing agent in the paper industry to increase the gloss and smoothness of paper; as an additive in the rubber industry to increase the lubricity and plasticity of rubber products, reduce the power consumption during processing and extend the service life of rubber products.

Peg 200 stearate is used as a surfactant, emulsifier (cosmetics, pharmaceuticals, textile finishes, defoamers, and baked goods), dye assistant, lubricant, and antistatic agent; Also used in dentifrice compositions and to make creams, lotions, ointments, and pharmaceutical preparations.
Peg 200 stearate is used as an excipient in many pharmaceutical products, in oral, topical, and parenteral dosage forms.
Peg 200 stearate is the basis of a number of laxatives (as MiraLax, RestoraLAX, etc.).

Whole bowel irrigation with Peg 200 stearate and added electrolytes is used for bowel preparation before surgery or colonoscopy or for children with constipation.
Macrogol (with brand names such as Laxido, GoLytely and Miralax) is the generic name for polyethylene glycol used as a laxative.
The name may be followed by a number which represents the average molecular weight (e.g. macrogol 3350, macrogol 4000 or macrogol 6000).

The possibility that PEG could be used to fuse axons is being explored by researchers studying peripheral nerve and spinal cord injury.
An example of Peg 200 stearates in a therapeutic has been theorized by Ma et al. They propose using the hydrogel to address periodontitis (gum disease) by encapsulating stem cells in the gel that promote healing in the gums.
The gel with encapsulated stem cells was to be injected into the site of disease and crosslinked to create the microenvironment required for the stem cells to function.

PEGylation of adenoviruses for gene therapy can help prevent adverse reactions due to pre-existing adenovirus immunity.
A Peg 200 stearate lipid is used as an excipient in both the Moderna and Pfizer–BioNTech vaccines for SARS-CoV-2.
Both RNA vaccines consist of messenger RNA, or mRNA, encased in a bubble of oily molecules called lipids.

Peg 200 stearate lipid technology is used for each.
Peg 200 stearate is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers.
Peg 200 stearate is frequently used to preserve waterlogged wood and other organic artifacts that have been salvaged from underwater archaeological contexts, as was the case with the warship Vasa in Stockholm, and similar cases.

Peg 200 stearate replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.
In addition, Peg 200 stearate is used when working with green wood as a stabilizer, and to prevent shrinkage.
Peg 200 stearate has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China.

These painted artifacts were created during the Qin Shi Huang (first emperor of China) era.
Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xi'an air.
The paint would subsequently flake off in about four minutes.

The German Bavarian State Conservation Office developed a Peg 200 stearate preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.
Peg 200 stearate is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning.
Peg 200 stearate derivatives, such as narrow range ethoxylates, are used as surfactants.

Peg 200 stearate has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.
Peg 200 stearate is a component of the propellent used in UGM-133M Trident II Missiles, in service with the United States Navy.
An example study was done using Peg 200 stearate-diacrylate hydrogels to recreate vascular environments with the encapsulation of endothelial cells and macrophages.

This model furthered vascular disease modeling and isolated macrophage phenotype's effect on blood vessels.
Peg 200 stearate is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.
Although polyethylene glycol is considered biologically inert, it can form non-covalent complexes with monovalent cations such as Na+, K+, Rb+, and Cs+, affecting equilibrium constants of biochemical reactions.

Peg 200 stearate is commonly used as a precipitant for plasmid DNA isolation and protein crystallization.
X-ray diffraction of protein crystals can reveal the atomic structure of the proteins.
Peg 200 stearate is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas.

In microbiology, Peg 200 stearate precipitation is used to concentrate viruses.
Peg 200 stearate is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro.
Gene therapy vectors (such as viruses) can be PEG-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect.

The size of the Peg 200 stearate polymer has been shown to be important, with larger polymers achieving the best immune protection.
Peg 200 stearate a nitrate ester-plasticized polyethylene glycol (NEPE-75) is used in Trident II submarine-launched ballistic missile solid rocket fuel.
Dimethyl ethers of Peg 200 stearate are the key ingredient of Selexol, a solvent used by coal-burning, integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the syngas stream.

Peg 200 stearate has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.
Peg 200 stearate is also used as a polymer host for solid polymer electrolytes.
Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving Peg 200 stearate, with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future.

Peg 200 stearate is injected into industrial processes to reduce foaming in separation equipment.
Peg 200 stearate is used as a binder in the preparation of technical ceramics.
Peg 200 stearate was used as an additive to silver halide photographic emulsions.

Peg 200 stearate is the basis of many skin creams (as cetomacrogol) and personal lubricants.
Peg 200 stearate is used in a number of toothpastes[5] as a dispersant. In this application, it binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste.
Peg 200 stearate is also under investigation for use in body armor, and in tattoos to monitor diabetes.

Polymer segments derived from Peg 200 stearate polyols impart flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam cushions.
In low-molecular-weight formulations (e.g. PEG 400), it is used in Hewlett-Packard designjet printers as an ink solvent and lubricant for the print heads.
Peg 200 stearate is also used as an anti-foaming agent in food and drinks[32] – its INS number is 1521[33] or E1521 in the EU.

Peg 200 stearate has been used in a study to assess the phase behaviors of special hot microemulsion to produce drug-loaded nanostructured lipid carriers.
Peg 200 stearate has also been used in a study to investigate its effects on multidrug resistance (MDR).
Peg 200 stearate has been used in a study to assess the phase behaviors of special hot microemulsion to produce drug-loaded nanostructured lipid carriers.

Peg 200 stearate has also been used in a study to investigate its effects on multidrug resistance (MDR).
Peg 200 stearate serves as an emulsifying agent, helping to blend water and oil-based ingredients in formulations.
This is particularly important in creams, lotions, and other skincare products where a stable and uniform texture is desired.

Peg 200 stearate contributes to the smoothness and spreadability of cosmetic and personal care products.
This enhances the sensory experience of applying creams, lotions, and other formulations.
Peg 200 stearate improves the stability of emulsions over time, preventing the separation of water and oil phases.

This is crucial for maintaining the integrity and appearance of the product throughout its shelf life.
Due to its emulsifying properties, products containing Peg 200 stearate can enhance hydration by effectively combining water and oil components.
This is beneficial for moisturizing and hydrating formulations.

Peg 200 stearate may be found in some cleansing products, contributing to the formulation's ability to remove dirt and oil from the skin.
Peg 200 stearate can act as a thickening agent, helping to give certain formulations a desired viscosity.
This is particularly useful in creating creams and lotions with a consistent and pleasant texture.

Peg 200 stearate can improve the solubility of certain ingredients in formulations, making it easier to incorporate a diverse range of components into a product.
Peg 200 stearate may enhance the absorption or penetration of other active ingredients into the skin.
This is particularly relevant in skincare products where the effective delivery of active compounds is important.

Peg 200 stearate is sometimes included in hair care products such as conditioners and styling products.
Peg 200 stearate is emulsifying properties can contribute to the even distribution of conditioning agents, improving the overall performance of the product.
Peg 200 stearate may be used to help disperse UV filters evenly, improving the product's effectiveness and providing a smoother application.

Peg 200 stearate is utilized in a wide range of cosmetic formulations, including foundations, concealers, and color cosmetics.
Peg 200 stearate is emulsifying and stabilizing properties contribute to the uniform blending of pigments and other ingredients.
Peg 200 stearate can be found in pharmaceutical ointments and topical medications.

Peg 200 stearate is emulsifying properties aid in the formulation of stable and easy-to-apply medicinal creams.
In certain wound care formulations, Peg 200 stearate may be used to improve the spreadability of the product and facilitate the application of active ingredients.
Peg 200 stearate is often chosen for formulations that include both water-soluble and oil-soluble active ingredients, as it helps create a compatible and effective product.

In some formulations, Peg 200 stearate can be used as an alternative to petroleum jelly.
Peg 200 stearate provides a similar smooth texture and emollient properties without the heavy feel associated with petroleum-based products.

Peg 200 stearate is used in various dermatological products, including moisturizers, anti-aging creams, and specialty skincare formulations.
Peg 200 stearate is emulsifying and stabilizing properties are valuable in maintaining product integrity.

Safety Profile:
Very slightly toxic by ingestion.
Questionable carcinogen with experimental tumorigenic data.
Experimental reproductive effects.

When heated to decomposition it emits acrid smoke and irritating fumes.
However, a growing body of evidence shows the existence of a detectable level of anti-Peg 200 stearate antibodies in approximately 72% of the population, never treated with PEGylated drugs, based on plasma samples from 1990 to 1999.

Due to its ubiquity in a multitude of products and the large percentage of the population with antibodies to PEG, hypersensitive reactions to Peg 200 stearate are an increasing concern.
Allergy to Peg 200 stearate is usually discovered after a person has been diagnosed with an allergy to an increasing number of seemingly unrelated products, including processed foods, cosmetics, drugs, and other substances that contain PEG or were manufactured with PEG.

PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) Properties of PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) Quality Level 200 vapor pressure <0.1 hPa ( 20 °C) autoignition temp. 370 °C potency 28000 mg/kg LD50, oral (Rat) >20000 mg/kg LD50, skin (Rabbit) pH 4-7 (20 °C, 100 g/L in H2O) bp >220 °C/1013 hPa (decomposes) mp -15--10 °C transition temp flash point 220 °C density 1.13 g/cm3 at 20 °C SMILES string C(CO)O InChI 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2 InChI key LYCAIKOWRPUZTN-UHFFFAOYSA-N storage conditions Store below +30°C. Name PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) Accession Number DB11161 Description Polyethylene glycol 300 (PEG 300) is a water-miscible polyether with an average molecular weight of 300 g/mol. It is a clear viscous liquid at room temperature with non-volatile, stable properties 1. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) are widely used in biochemistry, structural biology, and medicine in addition to pharmaceutical and chemical industries. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) serve as solubilizers, excipients, lubricants, and chemical reagents. Low molecular weight glycols are observed to exhibit antibacterial properties as well. PEG 300 is found in eye drops as a lubricant to temporarily relieve redness, burning and irritation of the eyes. Type Small Molecule Groups Approved Polyethylene glycol (PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300); /ˌpɒliˈɛθəlˌiːn ˈɡlaɪˌkɒl, -ˌkɔːl/) is a polyether compound with many applications, from industrial manufacturing to medicine. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight. The structure of PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is commonly expressed as H−(O−CH2−CH2)n−OH.[ Uses of Polyethylene glycol (PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) Medical uses of Polyethylene glycol (PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) Main article: Macrogol PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is the basis of a number of laxatives.[4] Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is also used as an excipient in many pharmaceutical products. When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood.[5] The possibility that PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) could be used to fuse axons is being explored by researchers studying peripheral nerve and spinal cord injury.[4] Chemical uses of Polyethylene glycol (PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) The remains of the 16th century carrack Mary Rose undergoing conservation treatment with PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) in the 1980s Terra cotta warrior, showing traces of original color Because PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is a hydrophilic molecule, it has been used to passivate microscope glass slides for avoiding non-specific sticking of proteins in single-molecule fluorescence studies.[6] Polyethylene glycol has a low toxicity and is used in a variety of products.[7] The polymer is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments.[8] Since PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures (on the order of tens of atmospheres). It also is unlikely to have specific interactions with biological chemicals. These properties make PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) one of the most useful molecules for applying osmotic pressure in biochemistry and biomembranes experiments, in particular when using the osmotic stress technique. Polyethylene glycol is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) has also been used to preserve objects that have been salvaged from underwater, as was the case with the warship Vasa in Stockholm,[9] and similar cases. It replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.[4] In addition, PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is used when working with green wood as a stabilizer, and to prevent shrinkage.[10] PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China.[11] These painted artifacts were created during the Qin Shi Huang (first emperor of China) era. Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xi'an air. The paint would subsequently flake off in about four minutes. The German Bavarian State Conservation Office developed a PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.[12] PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) derivatives, such as narrow range ethoxylates, are used as surfactants. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.[13] PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) has also been used as a propellent on the UGM-133M Trident II Missile, in service with the United States Air Force.[14] Biological uses PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.[6] PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is commonly used as a precipitant for plasmid DNA isolation and protein crystallization. X-ray diffraction of protein crystals can reveal the atomic structure of the proteins. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas. Polymer segments derived from PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) polyols impart flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam cushions. In microbiology, PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) precipitation is used to concentrate viruses. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro. Gene therapy vectors (such as viruses) can be PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300)-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect.[15] The size of the PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) polymer has been shown to be important, with larger polymers achieving the best immune protection. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is a component of stable nucleic acid lipid particles (SNALPs) used to package siRNA for use in vivo.[16][17] In blood banking, PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is used as a potentiator to enhance detection of antigens and antibodies.[4][18] When working with phenol in a laboratory situation, PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) 300 can be used on phenol skin burns to deactivate any residual phenol (some references are required). In biophysics, polyethylene glycols are the molecules of choice for the functioning ion channels diameter studies, because in aqueous solutions they have a spherical shape and can block ion channel conductance.[19][20] Commercial uses PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is the basis of many skin creams (as cetomacrogol) and personal lubricants (frequently combined with glycerin). PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is used in a number of toothpastes[4] as a dispersant. In this application, it binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is also under investigation for use in body armor, and in tattoos to monitor diabetes.[21][22] In low-molecular-weight formulations (e.g. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) 400), it is used in Hewlett-Packard designjet printers as an ink solvent and lubricant for the print heads. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is also used as an anti-foaming agent in food and drinks[23] – its INS number is 1521[24] or E1521 in the EU.[25] Industrial uses A nitrate ester-plasticized polyethylene glycol (NEPE-75) is used in Trident II submarine-launched ballistic missile solid rocket fuel.[26] Dimethyl ethers of PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) are the key ingredient of Selexol, a solvent used by coal-burning, integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the gas waste stream. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.[27] PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is also used as a polymer host for solid polymer electrolytes. Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300), with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is injected into industrial processes to reduce foaming in separation equipment. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is used as a binder in the preparation of technical ceramics.[28] Recreational uses PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is used to extend the size and durability of very large soap bubbles. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is the main ingredient in many personal lubricants. Health effects PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is considered biologically inert and safe by the FDA. However, a growing body of evidence shows the existence of anti PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) antibodies in approximately 72% of the population based on plasma samples from 1990–1999.[medical citation needed] The FDA has been asked to investigate the possible effects of PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) in laxatives for children.[29] Due to its ubiquity in a multitude of products and the large percentage of the population with antibodies to PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300), hypersensitive reactions to PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) are an increasing concern.[medical citation needed] Allergy to PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is usually discovered after a person has been diagnosed with an allergy to an increasing number of seemingly unrelated products, including processed foods, cosmetics, drugs, and other substances that contain PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) or were manufactured with PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300).[30] When PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is chemically attached to therapeutic molecules (such as protein drugs or nanoparticles), it can sometimes be antigenic, stimulating an anti-PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) antibody response in some patients. This effect has only been shown for a few of the many available PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300)ylated therapeutics, but it has significant effects on clinical outcomes of affected patients.[31] Other than these few instances where patients have anti-PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) immune responses, it is generally considered to be a safe component of drug formulations. Available forms and nomenclature PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300), PEO, and POE refer to an oligomer or polymer of ethylene oxide. The three names are chemically synonymous, but historically PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is preferred in the biomedical field, whereas PEO is more prevalent in the field of polymer chemistry. Because different applications require different polymer chain lengths, PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) has tended to refer to oligomers and polymers with a molecular mass below 20,000 g/mol, PEO to polymers with a molecular mass above 20,000 g/mol, and POE to a polymer of any molecular mass.[32] PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300)s are prepared by polymerization of ethylene oxide and are commercially available over a wide range of molecular weights from 300 g/mol to 10,000,000 g/mol.[33] PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) and PEO are liquids or low-melting solids, depending on their molecular weights. While PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) and PEO with different molecular weights find use in different applications, and have different physical properties (e.g. viscosity) due to chain length effects, their chemical properties are nearly identical. Different forms of PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) are also available, depending on the initiator used for the polymerization process – the most common initiator is a monofunctional methyl ether PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300), or methoxypoly(ethylene glycol), abbreviated mPEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300). Lower-molecular-weight PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300)s are also available as purer oligomers, referred to as monodisperse, uniform, or discrete. Very high purity PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) has recently been shown to be crystalline, allowing determination of a crystal structure by x-ray diffraction.[33] Since purification and separation of pure oligomers is difficult, the price for this type of quality is often 10–1000 fold that of polydisperse PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300). PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300)s are also available with different geometries. Branched PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300)s have three to ten PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) chains emanating from a central core group. Star PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300)s have 10 to 100 PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) chains emanating from a central core group. Comb PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300)s have multiple PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) chains normally grafted onto a polymer backbone. The numbers that are often included in the names of PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300)s indicate their average molecular weights (e.g. a PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) with n = 9 would have an average molecular weight of approximately 400 daltons, and would be labeled PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) 400.) Most PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300)s include molecules with a distribution of molecular weights (i.e. they are polydisperse). The size distribution can be characterized statistically by its weight average molecular weight (Mw) and its number average molecular weight (Mn), the ratio of which is called the polydispersity index (Mw/Mn). Mw and Mn can be measured by mass spectrometry. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300)ylation is the act of covalently coupling a PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) structure to another larger molecule, for example, a therapeutic protein, which is then referred to as a PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300)ylated protein. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300)ylated interferon alfa-2a or −2b are commonly used injectable treatments for hepatitis C infection. PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is soluble in water, methanol, ethanol, acetonitrile, benzene, and dichloromethane, and is insoluble in diethyl ether and hexane. It is coupled to hydrophobic molecules to produce non-ionic surfactants.[34] PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300)s potentially contain toxic impurities, such as ethylene oxide and 1,4-dioxane.[35] Ethylene Glycol and its ethers are nephrotoxic if applied to damaged skin.[36] Polyethylene oxide (PEO, Mw 4 kDa) nanometric crystallites (4 nm) Polyethylene glycol (PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300)) and related polymers (PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) phospholipid constructs) are often sonicated when used in biomedical applications. However, as reported by Murali et al., PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) is very sensitive to sonolytic degradation and PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) degradation products can be toxic to mammalian cells. It is, thus, imperative to assess potential PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) degradation to ensure that the final material does not contain undocumented contaminants that can introduce artifacts into experimental results.[37] PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300)s and methoxypolyethylene glycols are manufactured by Dow Chemical under the tradename Carbowax for industrial use, and Carbowax Sentry for food and pharmaceutical use. They vary in consistency from liquid to solid, depending on the molecular weight, as indicated by a number following the name. They are used commercially in numerous applications, including as surfactants, in foods, in cosmetics, in pharmaceutics, in biomedicine, as dispersing agents, as solvents, in ointments, in suppository bases, as tablet excipients, and as laxatives. Some specific groups are lauromacrogols, nonoxynols, octoxynols, and poloxamers. Macrogol, used as a laxative, is a form of polyethylene glycol. The name may be followed by a number which represents the average molecular weight. Production of Polyethylene glycol (PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) Polyethylene glycol 400, pharmaceutical quality Polyethylene glycol 4000, pharmaceutical quality The production of polyethylene glycol was first reported in 1859. Both A. V. Lourenço and Charles Adolphe Wurtz independently isolated products that were polyethylene glycols.[38] Polyethylene glycol is produced by the interaction of ethylene oxide with water, ethylene glycol, or ethylene glycol oligomers.[39] The reaction is catalyzed by acidic or basic catalysts. Ethylene glycol and its oligomers are preferable as a starting material instead of water, because they allow the creation of polymers with a low polydispersity (narrow molecular weight distribution). Polymer chain length depends on the ratio of reactants. HOCH2CH2OH + n(CH2CH2O) → HO(CH2CH2O)n+1H Depending on the catalyst type, the mechanism of polymerization can be cationic or anionic. The anionic mechanism is preferable because it allows one to obtain PEG 300 (Polyethylene Glycol 300, Polietilen Glikol 300) with a low polydispersity. Polymerization of ethylene oxide is an exothermic process. Overheating or contaminating ethylene oxide with catalysts such as alkalis or metal oxides can lead to runaway polymerization, which can end in an explosion after a few hours. Polyethylene oxide, or high-molecular weight polyethylene glycol, is synthesized by suspension polymerization. It is necessary to hold the growing polymer chain in solution in the course of the polycondensation process. The reaction is catalyzed by magnesium-, aluminium-, or calcium-organoelement compounds. To prevent coagulation of polymer chains from solution, chelating additives such as dimethylglyoxime are used. Alkaline catalysts such as sodium hydroxide (NaOH), potassium hydroxide (KOH), or sodium carbonate (Na2CO3) are used to prepare low-molecular-weight polyethylene glycol.

cas no 86893-19-8 Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, ether with methyl d-glucopyranoside 2,6-bis[(Z)-9-octadecenoate] (2:1) (120 mol EO average molar ratio); polyethylene glycol (120) methyl glucoside dioleate; PEG-120 methyl glucose dioleate; Macrogol 120 methyl glucose dioleate; POE (120) methyl glucose dioleate;

PEG; Macrogol; Polyoxyethlene; Aquaffin; Nycoline; alpha-hydro-omega-hydroxypoly(oxy-1,2-ethanediyl); polyethylene glycols; Poly Ethylene Oxide; Polyoxyethylene; Polyglycol; 1,2-ethanediol Ehoxylated; Polyoxyethylene ether; Polyoxyethylene; Poly(ethylene glycol); PEG 300; PEG 400; PEG 1500; PEG 6000; PEG 8000 CAS NO: 25322-68-3

PEG 3350 Polyethylene glycol (PEG 3350; /ˌpɒliˈɛθəlˌiːn ˈɡlaɪˌkɒl, -ˌkɔːl/) is a polyether compound with many applications, from industrial manufacturing to medicine. PEG 3350 is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight. The structure of PEG 3350 is commonly expressed as H−(O−CH2−CH2)n−OH. Uses of Polyethylene glycol (PEG 3350 Medical uses of Polyethylene glycol (PEG 3350) Main article: Macrogol PEG 3350 is the basis of a number of laxatives.[4] Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy. PEG 3350 is also used as an excipient in many pharmaceutical products. When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood.[5] The possibility that PEG 3350 could be used to fuse axons is being explored by researchers studying peripheral nerve and spinal cord injury.[4] Chemical uses of Polyethylene glycol (PEG 3350) The remains of the 16th century carrack Mary Rose undergoing conservation treatment with PEG 3350 in the 1980s Terra cotta warrior, showing traces of original color Because PEG 3350 is a hydrophilic molecule, it has been used to passivate microscope glass slides for avoiding non-specific sticking of proteins in single-molecule fluorescence studies.[6] Polyethylene glycol has a low toxicity and is used in a variety of products.[7] The polymer is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments.[8] Since PEG 3350 is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures (on the order of tens of atmospheres). It also is unlikely to have specific interactions with biological chemicals. These properties make PEG 3350 one of the most useful molecules for applying osmotic pressure in biochemistry and biomembranes experiments, in particular when using the osmotic stress technique. Polyethylene glycol is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers. PEG 3350 has also been used to preserve objects that have been salvaged from underwater, as was the case with the warship Vasa in Stockholm,[9] and similar cases. It replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.[4] In addition, PEG 3350 is used when working with green wood as a stabilizer, and to prevent shrinkage.[10] PEG 3350 has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China.[11] These painted artifacts were created during the Qin Shi Huang (first emperor of China) era. Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xi'an air. The paint would subsequently flake off in about four minutes. The German Bavarian State Conservation Office developed a PEG 3350 preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.[12] PEG 3350 is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning. PEG 3350 derivatives, such as narrow range ethoxylates, are used as surfactants. PEG 3350 has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.[13] PEG 3350 has also been used as a propellent on the UGM-133M Trident II Missile, in service with the United States Air Force.[14] Biological uses PEG 3350 is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.[6] PEG 3350 is commonly used as a precipitant for plasmid DNA isolation and protein crystallization. X-ray diffraction of protein crystals can reveal the atomic structure of the proteins. PEG 3350 is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas. Polymer segments derived from PEG 3350 polyols impart flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam cushions. In microbiology, PEG 3350 precipitation is used to concentrate viruses. PEG 3350 is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro. Gene therapy vectors (such as viruses) can be PEG 3350-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect.[15] The size of the PEG 3350 polymer has been shown to be important, with larger polymers achieving the best immune protection. PEG 3350 is a component of stable nucleic acid lipid particles (SNALPs) used to package siRNA for use in vivo. In blood banking, PEG 3350 is used as a potentiator to enhance detection of antigens and antibodies. When working with phenol in a laboratory situation, PEG 3350 300 can be used on phenol skin burns to deactivate any residual phenol (some references are required). In biophysics, polyethylene glycols are the molecules of choice for the functioning ion channels diameter studies, because in aqueous solutions they have a spherical shape and can block ion channel conductance. Commercial uses PEG 3350 is the basis of many skin creams (as cetomacrogol) and personal lubricants (frequently combined with glycerin). PEG 3350 is used in a number of toothpastes[4] as a dispersant. In this application, it binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste. PEG 3350 is also under investigation for use in body armor, and in tattoos to monitor diabetes. In low-molecular-weight formulations (e.g. PEG 3350 400), it is used in Hewlett-Packard designjet printers as an ink solvent and lubricant for the print heads. PEG 3350 is also used as an anti-foaming agent in food and drinks[23] – its INS number is 1521 or E1521 in the EU. Industrial uses A nitrate ester-plasticized polyethylene glycol (NEPE-75) is used in Trident II submarine-launched ballistic missile solid rocket fuel.[26] Dimethyl ethers of PEG 3350 are the key ingredient of Selexol, a solvent used by coal-burning, integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the gas waste stream. PEG 3350 has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.[27] PEG 3350 is also used as a polymer host for solid polymer electrolytes. Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving PEG 3350, with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future. PEG 3350 is injected into industrial processes to reduce foaming in separation equipment. PEG 3350 is used as a binder in the preparation of technical ceramics.[28] Recreational uses PEG 3350 is used to extend the size and durability of very large soap bubbles. PEG 3350 is the main ingredient in many personal lubricants. Health effects PEG 3350 is considered biologically inert and safe by the FDA. However, a growing body of evidence shows the existence of anti PEG 3350 antibodies in approximately 72% of the population based on plasma samples from 1990–1999.[medical citation needed] The FDA has been asked to investigate the possible effects of PEG 3350 in laxatives for children.[29] Due to its ubiquity in a multitude of products and the large percentage of the population with antibodies to PEG 3350, hypersensitive reactions to PEG 3350 are an increasing concern.[medical citation needed] Allergy to PEG 3350 is usually discovered after a person has been diagnosed with an allergy to an increasing number of seemingly unrelated products, including processed foods, cosmetics, drugs, and other substances that contain PEG 3350 or were manufactured with PEG 3350.[30] When PEG 3350 is chemically attached to therapeutic molecules (such as protein drugs or nanoparticles), it can sometimes be antigenic, stimulating an anti-PEG 3350 antibody response in some patients. This effect has only been shown for a few of the many available PEG 3350 therapeutics, but it has significant effects on clinical outcomes of affected patients.[31] Other than these few instances where patients have anti-PEG 3350 immune responses, it is generally considered to be a safe component of drug formulations. Available forms and nomenclature PEG 3350, PEO, and POE refer to an oligomer or polymer of ethylene oxide. The three names are chemically synonymous, but historically PEG 3350 is preferred in the biomedical field, whereas PEO is more prevalent in the field of polymer chemistry. Because different applications require different polymer chain lengths, PEG 3350 has tended to refer to oligomers and polymers with a molecular mass below 20,000 g/mol, PEO to polymers with a molecular mass above 20,000 g/mol, and POE to a polymer of any molecular mass.[32] PEG 3350s are prepared by polymerization of ethylene oxide and are commercially available over a wide range of molecular weights from 300 g/mol to 10,000,000 g/mol.[33] PEG 3350 and PEO are liquids or low-melting solids, depending on their molecular weights. While PEG 3350 and PEO with different molecular weights find use in different applications, and have different physical properties (e.g. viscosity) due to chain length effects, their chemical properties are nearly identical. Different forms of PEG 3350 are also available, depending on the initiator used for the polymerization process – the most common initiator is a monofunctional methyl ether PEG 3350, or methoxypoly(ethylene glycol), abbreviated mPEG 3350. Lower-molecular-weight PEG 3350s are also available as purer oligomers, referred to as monodisperse, uniform, or discrete. Very high purity PEG 3350 has recently been shown to be crystalline, allowing determination of a crystal structure by x-ray diffraction.[33] Since purification and separation of pure oligomers is difficult, the price for this type of quality is often 10–1000 fold that of polydisperse PEG 3350. PEG 3350s are also available with different geometries. Branched PEG 3350s have three to ten PEG 3350 chains emanating from a central core group. Star PEG 3350s have 10 to 100 PEG 3350 chains emanating from a central core group. Comb PEG 3350s have multiple PEG 3350 chains normally grafted onto a polymer backbone. The numbers that are often included in the names of PEG 3350s indicate their average molecular weights (e.g. a PEG 3350 with n = 9 would have an average molecular weight of approximately 400 daltons, and would be labeled PEG 3350 400.) Most PEG 3350s include molecules with a distribution of molecular weights (i.e. they are polydisperse). The size distribution can be characterized statistically by its weight average molecular weight (Mw) and its number average molecular weight (Mn), the ratio of which is called the polydispersity index (Mw/Mn). Mw and Mn can be measured by mass spectrometry. PEG 3350ylation is the act of covalently coupling a PEG 3350 structure to another larger molecule, for example, a therapeutic protein, which is then referred to as a PEG 3350 protein. PEG 3350 interferon alfa-2a or −2b are commonly used injectable treatments for hepatitis C infection. PEG 3350 is soluble in water, methanol, ethanol, acetonitrile, benzene, and dichloromethane, and is insoluble in diethyl ether and hexane. It is coupled to hydrophobic molecules to produce non-ionic surfactants.[34] PEG 3350s potentially contain toxic impurities, such as ethylene oxide and 1,4-dioxane.[35] Ethylene Glycol and its ethers are nephrotoxic if applied to damaged skin.[36] Polyethylene oxide (PEO, Mw 4 kDa) nanometric crystallites (4 nm) Polyethylene glycol (PEG 3350) and related polymers (PEG 3350 phospholipid constructs) are often sonicated when used in biomedical applications. However, as reported by Murali et al., PEG 3350 is very sensitive to sonolytic degradation and PEG 3350 degradation products can be toxic to mammalian cells. It is, thus, imperative to assess potential PEG 3350 degradation to ensure that the final material does not contain undocumented contaminants that can introduce artifacts into experimental results.[37] PEG 3350s and methoxypolyethylene glycols are manufactured by Dow Chemical under the tradename Carbowax for industrial use, and Carbowax Sentry for food and pharmaceutical use. They vary in consistency from liquid to solid, depending on the molecular weight, as indicated by a number following the name. They are used commercially in numerous applications, including as surfactants, in foods, in cosmetics, in pharmaceutics, in biomedicine, as dispersing agents, as solvents, in ointments, in suppository bases, as tablet excipients, and as laxatives. Some specific groups are lauromacrogols, nonoxynols, octoxynols, and poloxamers. Macrogol, used as a laxative, is a form of polyethylene glycol. The name may be followed by a number which represents the average molecular weight. Production of Polyethylene glycol (PEG 3350) Polyethylene glycol 400, pharmaceutical quality Polyethylene glycol 4000, pharmaceutical quality The production of polyethylene glycol was first reported in 1859. Both A. V. Lourenço and Charles Adolphe Wurtz independently isolated products that were polyethylene glycols.[38] Polyethylene glycol is produced by the interaction of ethylene oxide with water, ethylene glycol, or ethylene glycol oligomers.[39] The reaction is catalyzed by acidic or basic catalysts. Ethylene glycol and its oligomers are preferable as a starting material instead of water, because they allow the creation of polymers with a low polydispersity (narrow molecular weight distribution). Polymer chain length depends on the ratio of reactants. HOCH2CH2OH + n(CH2CH2O) → HO(CH2CH2O)n+1H Depending on the catalyst type, the mechanism of polymerization can be cationic or anionic. The anionic mechanism is preferable because it allows one to obtain PEG 3350 with a low polydispersity. Polymerization of ethylene oxide is an exothermic process. Overheating or contaminating ethylene oxide with catalysts such as alkalis or metal oxides can lead to runaway polymerization, which can end in an explosion after a few hours. Polyethylene oxide, or high-molecular weight polyethylene glycol, is synthesized by suspension polymerization. It is necessary to hold the growing polymer chain in solution in the course of the polycondensation process. The reaction is catalyzed by magnesium-, aluminium-, or calcium-organoelement compounds. To prevent coagulation of polymer chains from solution, chelating additives such as dimethylglyoxime are used. Alkaline catalysts such as sodium hydroxide (NaOH), potassium hydroxide (KOH), or sodium carbonate (Na2CO3) are used to prepare low-molecular-weight polyethylene glycol. Polyethylene glycol (PEG 3350) is a versatile polyether being utilized in various applications, in particular in medicine. Polyethylene oxide (PEO) is another name for PEG 3350. Typically, ethylene oxide macromolecules (Fig. 18.9) with molecular weights less than 20,000 g/mol are called PEG 3350, while those having values above 20,000 g/mol are named PEO. It is reported that PEG 3350 is soluble in water, ethanol, acetonitrile, benzene, and dichloromethane, while it is insoluble in diethyl ether and hexane. PEG 3350 is available in different structures such as branched, star, and comb-like macromolecules. PEG 3350ylation is an attractive process in which PEG 3350 is bonded to another molecule, which is promising in therapeutic methods. PEG 3350 can hinder the protein adsorption which is essential in drug delivery to minimize the protein corona formation [29]. Polyethylene glycol (PEG 3350) is a hydrophilic polymer of ethylene oxide. The non-immunogenic, biocompatible and flexible nature of PEG 3350 makes it a suitable synthetic dressing material for wound healing. The low toxic PEG 3350 macromers are well bonded with growth factor like EGF and can be delivered at the wound site [98]. The mechanical stability of PEG 3350 can be enhanced by blending PEG 3350 with chitosan and PLGA. Blending also increases thermal stability and crystallinity of the particular polymer [99]. Such PEG 3350-based dressings have been widely used to treat a diabetic wound by promoting and inducing growth of skin cells and collagen deposition. It also reduces scar formation [100]. The injectable hybrid hydrogel dressing system is developed from PEG 3350-based hyperbranched multiacrylated co-polymer and HA in combination with adipose-derived stem cells to support the viability of cells in vitro and in vivo. It prevents wound contraction and enhances angiogenesis by acting as temporary hydrogel for wound healing purpose [101]. Hydrophilic Materials Based on Polyethylene Glycol Polyethylene glycol (PEG 3350) is the most relevant antifouling polymer in biomedical devices. PEG 3350 antifouling properties are thought to be related to surface hydration and steric hindrance effects (Chen et al., 2010). PEG 3350 chains linked to a material surface assume a brush-like configuration at the water/surface interface, limiting the approach to the surface by bacteria. Compression of the highly hydrated layer of PEG 3350 chains is unfavorable because it would involve a reduction in PEG 3350 chain mobility and removal of water molecules. Surface packing density and polymer chain length can be used to control PEG 3350 antifouling properties (Roosjen et al., 2004). PEG 3350-functionalized PUs were developed by PEG 3350 introduction either in the polymer backbone (Corneillie et al., 1998) or polymer side chain (Francolini et al., 2019). Auto-oxidization in the presence of oxygen, metal ions, and enzymes able to oxidize PEG 3350 hydroxyl groups, however, may limit long-term effectiveness. Polyethylene glycol (PEG 3350) is another important type of PCM for textile applications. The repeating unit in PEG 3350 is oxyethylene (–O–CH2–CH2–) containing hydroxyl group on either side of the chain. The melting point of PEG 3350 depends on its molecular weight and is proportional as the molecular weight increases. The phase-change temperature of PEG 3350 can be determined using DSC (Pielichowski and Flejtuch, 2002). PEG 3350 with degree of polymerization 1000 has phase-change temperature of 35°C, while PEG 3350 with degree of polymerization 20,000 has melting temperature of 63°C (Craig and Newton, 1991; Hopp et al., 2000). Jiang et al. (2016) synthesized a dual-functional magnetic microcapsules containing a PCM core and an organo-silica shell for the electromagnetic shielding and thermal regulating applications. Fig. 20.6 shows the resulting DSC curves where the areas under the peaks indicate the amount of latent heat contained using different organosilanes/PEG 3350 weight ratios. PEG 3350 is the basis of a number of laxatives.[3] Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy. PEG 3350 is also used as an excipient in many pharmaceutical products. When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood.[4] The possibility that PEG 3350 could be used to fuse nerve cells is being explored by researchers studying spinal cord injury.[3] Chemical uses The remains of the 16th century carrack Mary Rose undergoing conservation treatment with PEG 3350 in the 1980s Terra cotta warrior, showing traces of original color Because PEG 3350 is a hydrophilic molecule, it has been used to passivate microscope glass slides for avoiding non-specific sticking of proteins in single-molecule fluorescence studies.[5] Polyethylene glycol has a low toxicity and is used in a variety of products.[6] The polymer is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments.[7] Since PEG is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures (on the order of tens of atmospheres). It also is unlikely to have specific interactions with biological chemicals. These properties make PEG 3350 one of the most useful molecules for applying osmotic pressure in biochemistry and biomembranes experiments, in particular when using the osmotic stress technique. Polyethylene glycol is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers. PEG 3350 has also been used to preserve objects that have been salvaged from underwater, as was the case with the warship Vasa in Stockholm,[8] and similar cases. It replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.[3] In addition, PEG 3350 is used when working with green wood as a stabilizer, and to prevent shrinkage.[9] PEG has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China.[10] These painted artifacts were created during the Qin Shi Huang Di dynasty (first emperor of China). Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xian air. The paint would subsequently flake off in about four minutes. The German Bavarian State Conservation Office developed a PEG 3350 preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.[11] PEG 3350 is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning. PEG 3350 derivatives, such as narrow range ethoxylates, are used as surfactants. PEG 3350 is a polyol and can be reacted with an isocyanate to make polyurethane. PEG 3350 has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.[12] Biological uses PEG 3350 is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions. PEG 3350 is commonly used as a precipitant for plasmid DNA isolation and protein crystallization. X-ray diffraction of protein crystals can reveal the atomic structure of the proteins. PEG is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas. César Milstein and Georges J. F. Köhler originated this technique, which they used for antibody production, winning a Nobel Prize in Physiology or Medicine in 1984.[3] Polymer segments derived from PEG polyols impart flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam cushions. In microbiology, PEG 3350 precipitation is used to concentrate viruses. PEG is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro. Gene therapy vectors (such as viruses) can be PEG-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect.[13] The size of the PEG polymer has been shown to be important, with larger polymers achieving the best immune protection. PEG is a component of stable nucleic acid lipid particles (SNALPs) used to package siRNA for use in vivo. In blood banking, PEG is used as a potentiator to enhance detection of antigens and antibodies.[3][16] When working with phenol in a laboratory situation, PEG 300 can be used on phenol skin burns to deactivate any residual phenol. In biophysics, polyethylene glycols are the molecules of choice for the functioning ion channels diameter studies, because in aqueous solutions they have a spherical shape and can block ion channel conductance. What is Polyethyleneglycol? Polyethyleneglycol, or PEG 3350 for short, is a polyether consisting of a (-O-CH2-CH2-) backbone that is commonly used in many fields of academic research, industrial processing and commercial applications. PEG 3350s can also commonly be referred to as polyoxyethylene (POE) and polyethyleneoxide (PEO), but regardless of the name that is used, the simple structure of PEG 3350s (which consists of solely carbon, hydrogen and oxygen, see image below) affords safe compounds that are used throughout everyday life. Additionally, it is this simple structure that separates PEG 3350s from similar compounds like propylene glycol and polypropyleneglycol. The two aforementioned compounds (polyethyleneglycol vs. propylene glycol) are derivatives of propylene oxide, which, when polymerized, bestows a completely different set of physical characteristics to the compound as compared to PEG 3350. The method in which PEG 3350s are created allows for a wide variability in their physical attributes, allowing them to be utilized by many commercial markets. By controlling a PEG 3350’s size (i.e. molecular weight) and its size distribution, a wide variety of physical properties can be achieved, which sets Oxiteno’s line of PEG 3350 products, the 6000 powder series, apart from other name brands of polyethyleneglycols. Due to the vast number of product types offered 6000 powder products (click here for a full listing), many physical forms (liquids, pastes, solids, flakes, powder, etc.) and viscosities of PEG 3350s are available. It is the numerous attributes of PEG 3350s that allow for their inclusion in a vast array of applications, ranging from the pharmaceutical industry to cosmetic markets. While the structure of PEG 3350 is simple, it is this compound’s solubility in water is what makes it such a versatile additive to enhance many industrial applications. Because line of PEG 3350 products are non-toxic and hydrophilic (water-loving), these polymers are used in the home (i.e. to treat surfaces in cleaning agents made by cleaning chemicals manufacturers) as well as in the food production industry (to reduce the amount of foam during the processing of food products). PEG 3350s are generally considered to be biologically inert, making them safe to use throughout the medical and food-processing industries. What is Polyethyleneglycol Used For? Due to the variety of physical properties that can be achieved through PEG 3350 series, formulators in nearly all industries can benefit from this line of PEG 3350 products. A PEG 3350’s unique ability to enhance a dye’s solubility in aqueous formulations causes it to be used throughout the textile industry as dye carriers. PEG 3350s are also exceptional at retaining moisture in complex formulations, as well as to an applied surface, making them excellent humectants and anti-caking agents for cosmetic chemical suppliers and coatings chemical suppliers. This unique relationship with water is further exploited by many other markets as PEG 3350s can help to stabilize emulsions and act as water-miscible co-solvents for aqueous formulations. The food industry uses these compounds as additives to reduce the amount of foam during food processing. Additionally, PEG 3350s find themselves very useful in the pharmaceutical industry due to their ability to act as rheological modifiers, thus being used as excipients. New research techniques are increasingly incorporating PEG 3350 compounds via the use of ‘PEG 3350ylation’ onto protein and peptide therapeutics, thus improving their pharmacokinetics and leading to safer and more effective drugs1-2. Many of PEG 3350 series meet the requirements set forth by the National Formulary (NF) guidelines for safe preparation, manufacture and use of a variety of PEG 3350 compounds that can be used as excipients, botanicals and other similar products. Is Polyethyleneglycol Safe? PEG 3350s are generally considered to be a biologically inert substance, meaning that this class of oligomers and polymers are recognized to be safe for use in food, cosmetic and pharmaceutical applications. So, is polyethyleneglycol toxic? Due to the PEG 3350’s structure and its water solubility, these compounds are generally considered to be non-toxic, as studies of demonstrated their safety for use within the field of drug delivery1-2, for application to the skin in cosmetics3 and as additives in the food and vitamin processing industry4. Where applicable, line of PEG 3350s, 6000 powder, adhere to the guidelines for the manufacturing set forth by the National Formulary (NF). Having initially been established by the U.S. Federal Food, Drug, and Cosmetics Act of 1938, these guidelines are currently recognized by the U.S. Food and Drug Administration (FDA). These manufacturing and production guidelines are annually reviewed, requiring to not only adhere to these strict standards, but maintain constant surveillance over the preparation of these non-toxic additives. Additionally, many of PEG 3350 products that are used in agricultural applications are safe for the environment and are on the Environmental Protection Agencies’ (EPA) inert ingredient list, meeting the requirements set forth in 40 CFR 180.910 and 40 CFR 180.930. This makes PEG 3350s attractive for agrochemical companies. Polyethylene Glycol · Adhesives · Agriculture · Ceramics · Chemical Intermediates · Cosmetics · Toiletries · Electroplating / Electropolishing · Food Processing · Household Products · Lubricants · Metal / Metal Fabrication · Paints & Coatings · Paper Industry · Pharmaceuticals · Printing · Rubber & Elastomers · Textiles · Wood Processing AVAILABLE FORMS AND NOMENCLATURE PEG 3350, PEO, and POE refer to an oligomer or polymer of ethylene oxide. The three names are chemically synonymous, but historically PEG 3350 is preferred in the biomedical field, whereas PEO is more prevalent in the field of polymer chemistry. Because different applications require different polymer chain lengths, PEG 3350 has tended to refer to oligomers and polymers with a molecular mass below 20,000 g/mol, PEO to polymers with a molecular mass above 20,000 g/mol, and POE to a polymer of any molecular mass PEG 3350s are prepared by polymerization of ethylene oxide and are commercially available over a wide range of molecular weights from 300 g/mol to 10,000,000 g/mol.[ PEG 3350 and PEO are liquids or low-melting solids, depending on their molecular weights. While PEG 3350 and PEO with different molecular weights find use in different applications, and have different physical properties (e.g. viscosity) due to chain length effects, their chemical properties are nearly identical. Different forms of PEG 3350 are also available, depending on the initiator used for the polymerization process - the most common initiator is a monofunctional methyl ether PEG 3350, or methoxypoly(ethylene glycol), abbreviated mPEG 3350. Lower-molecular-weight PEG 3350s are also available as purer oligomers, referred to as monodisperse, uniform, or discrete. Very high purity PEG 3350 has recently been shown to be crystalline, allowing determination of a crystal structure by x-ray diffraction Since purification and separation of pure oligomers is difficult, the price for this type of quality is often 10-1000 fold that of polydisperse PEG 3350. PEG 3350s are also available with different geometries. The numbers that are often included in the names of PEG 3350s indicate their average molecular weights (e.g. a PEG 3350 with n = 9 would have an average molecular weight of approximately 400 daltons, and would be labeled PEG 3350 400.) Most PEG 3350s include molecules with a distribution of molecular weights (i.e. they are polydisperse). The size distribution can be characterized statistically by its weight average molecular weight (Mw) and its number average molecular weight (Mn), the ratio of which is called the polydispersity index(Mw/Mn). Mw and Mn can be measured by mass spectrometry. PEG 3350 is the act of covalently coupling a PEG 3350 structure to another larger molecule, for example, a therapeutic protein, which is then referred to as a PEG 3350 protein. PEG 3350 interferon alfa-2a or -2b are commonly used injectable treatments for hepatitis C infection. PEG 3350 is soluble in water, methanol, ethanol, acetonitrile, benzene, and dichloromethane, and is insoluble in diethyl ether and hexane. It is coupled to hydrophobic molecules

Composition: Polyethylene glycol 3350 (PEG 3350)

H(OCH2CH2)nOH

n = about 76

CAS-No.: 25322-68-3

INCI-designation: PEG-75

Product properties*)
Polyglykol 3350 is a white waxy solid at room temperature.

Its two hydroxy end groups and its ether groups mainly control the physical and chemical properties of Polyethylene Glycol 3350.

Therefore, Polyethylene Glycol 3350 is soluble in water and polar organic solvents like acetone or methanol.

Polyethylene Glycol 3350 is insoluble in pure hydrocarbons.

Polyethylene Glycol 3350 displays typical chemical reactions of alcohols/diols.

The solidification point of Polyethylene Glycol 3350 is about 55°C.

Storage
Polyethylene Glycol 3350 can be kept for at least two years when stored in a closed container in a cold, dry place.


Applications
Polyethylene glycol 3350 is used in various applications:

Fields of application:
- Reactive diol/polyether components in polyester or polyurethane resins
- Component of auxiliaries for leather and textile processing
- Cosmetic/pharmaceutical formulations (e.g., humectant or plasticizer for creams, tablets, toothpaste)
- Lubricant and mould release agent for rubber and elastomer processing
- Plasticizer and binder for ceramic and concrete manufacturing
- Component of lubricant formulations
- Water soluble, lubricating component in metalworking fluids
- Humectant for paper, wood, and cellulose films
- Solvent and humectant for dyes and inks
- Modifier for the production of regenerated viscose
- Humectant and plasticizer for adhesives



Product data*)
water content (DIN 51777) % m/m: max. 0.5
Color index APHA(EN 1557) (25 % in water): max. 30
pH ( 5 % w/w in water) (DIN EN 1262): 5 – 7
hydroxyl number (DIN 53240) mg KOH/g: 30 – 37
molecular weight g/mol: 3050 – 3685
solidification point (EP III) °C: 53 – 57
viscosity at 20°C (50 % w/w in water) (DIN 51562) mPas: 85 – 105
flash point (DIN 51376) °C: 260
ignition temperature (DIN 51794) °C : >320
ethylene oxide ppm: max. 1
dioxane ppm: max. 1

PEG-4 Rapeseedamide is a water-soluble surfactant derived from Rapeseed oil.
Commonly used in cosmetic formulations, PEG-4 Rapeseedamide enhances product spreadability, foaming capabilities, and emulsification.
With gentle cleansing properties and high biodegradability, PEG-4 Rapeseedamide promotes sustainability and skin compatibility, making it ideal for eco-conscious personal care products.

CAS: 85536-23-8

PEG-4 Rapeseedamide is a common ingredient in personal care products.
PEG-4 Rapeseedamide is primarily a surfactant that helps reduce the surface tension between water and the surface to effectively remove dirt and dust.
PEG-4 Rapeseedamide is also responsible for creating a rich creamy lather that improves the feel of the product.
Overall, PEG-4 Rapeseedamide enhances the cleansing properties of any personal care product or cosmetics.
PEG-4 Rapeseedamide appears as a slightly yellowish liquid that has a mild odor and is soluble in water.
PEG-4 Rapeseedamide's chemical formula is C23H45NO6.

PEG-4 Rapeseedamide is a liquid at room temperature.
PEG-4 Rapeseedamide's colour varies from light yellow to orange.
When added to water, it does not dissolve but forms a dispersion, i.e. PEG-4 Rapeseedamide disperses as fine droplets throughout a homogeneous liquid medium.
The density of a pure ingredient is approx. 1.00 g/mL, at the temperature of 25ᵒC.
The liquid PEG-4 Rapeseedamide solidifies at the temperature of approx. 0ᵒC.

Due to its emulsifying properties, PEG-4 Rapeseedamide acts as a co-emulsifier in O/W (oil-in-water) emulsions.
As an ingredient of an emulsion, PEG-4 Rapeseedamide supports the other components responsible for generating the emulsion, which results from the formation of systems of two mutually insoluble phases.
Those phases are usually oil and water.
Due to the co-emulsifying effect of PEG-4 Rapeseedamide, emulsions are more stable and have the required consistency which facilitates their application.

As a surfactant, PEG-4 Rapeseedamide is also a stabiliser and enhances the quality of foam in mixtures with anionic surfactants.
Emulsions are thermodynamic systems that are unstable by nature; therefore, it is necessary to use stabilisers such as PEG-4 Rapeseedamide.
The forces acting between the droplets of the dispersed phase may be strong enough to cause self-agglomeration of the dispersed phase particles, resulting in the separation of the product e.g. a cream into layers.
This in turn will prevent its proper application.
The role of a surfactant is to create as large boundary surface areas as possible and to spread the dispersed phase particles.

PEG-4 Rapeseedamide is an ingredient of delicate products for washing the skin and hair.
Products that contain this surfactant have a reduced irritant potential and thus are designed for the care of especially sensitive areas.
PEG-4 Rapeseedamide also has the thickening function in products.
PEG-4 Rapeseedamide's purpose is to give the product the appropriate consistency.
Moreover, PEG-4 Rapeseedamide is effective both in preparations with an SLES (a strong surfactant) and in preparations without any surfactants.

PEG-4 Rapeseedamide is a high concentrated liquid surfactant which shows very good solubilizing and emulsifying properties.
PEG-4 Rapeseedamidepresents better performance in terms of thickening and foaming than Cocamide DEA.
PEG-4 Rapeseedamide is the polyethylene glycol amide of the fatty acids derived from rapeseed oil.

Synonyms
Amides, rape-oil, N-(hydroxyethyl), ethoxylated
85536-23-8
DTXSID201041786
Rüblmonoethanolamid, ethoxyliert (3-4 EO)

Peg 4 rapeseedamide appears as a slightly yellowish liquid that has a mild odor and is soluble in water.
Peg 4 Rapeseedamide is quite a useful ingredient in the cosmetic industry.
Peg 4 rapeseedamide is primarily a surfactant that helps reduce the surface tension between water and the surface to effectively remove dirt and dust.

CAS Number: 85536-23-8
Molecular Formula: C18H30O3S

Peg 4 rapeseedamide is a common ingredient in personal care products.
Peg 4 rapeseedamide is also responsible for creating a rich creamy lather that improves the feel of the product.
Overall, this ingredient enhances the cleansing properties of any personal care product or cosmetics.

Peg 4 rapeseedamide is chemical formula is C23H45NO6.
Peg 4 rapeseedamide is made by the reaction of rapeseed oil with ethylene oxide and amines.
This water-soluble ingredient appears in liquid form that is clear or slightly yellow in color.

Peg 4 rapeseedamide is a mild surfactant that is used in products like shampoos, facial cleansers, and body washes for effective cleaning purposes.
Peg 4 rapeseedamide enhances the texture and the foam quality of the products to give the users a luxurious and satisfying experience.
Peg 4 rapeseedamide also acts as a thickener by increasing the viscosity and improving the spreadability of the products.

Peg 4 rapeseedamide is great for stabilizing oil in water emulsions like creams and lotions.
Peg 4 rapeseedamide has some moisturizing properties that leave the hair and skin hydrated and more soft.
Peg 4 rapeseedamide is a water-soluble surfactant derived from Rapeseed oil.

Commonly used in cosmetic formulations, Peg 4 rapeseedamide enhances product spreadability, foaming capabilities, and emulsification.
With gentle cleansing properties and high biodegradability, Peg 4 rapeseedamide promotes sustainability and skin compatibility, making it ideal for eco-conscious personal care products.
Peg 4 rapeseedamide is a non-ionic surfactant that belongs to the group of ethoxylated alkanolamides.

Peg 4 rapeseedamide is a name in the International Nomenclature of Cosmetic Ingredients (INCI) system.
Peg 4 rapeseedamide is an ethoxylated rapeseed oil fatty acids monoethanolamide.
The CAS number, i.e. the reference number assigned by the US organisation Chemical Abstracts Service, for this substance is 85536-23-8.

PEG-4 Rapeseedamide is a liquid at room temperature.
Peg 4 rapeseedamide is colour varies from light yellow to orange.
When added to water, Peg 4 rapeseedamide does not dissolve but forms a dispersion, i.e. it disperses as fine droplets throughout a homogeneous liquid medium.

The density of a pure ingredient is approx.
The liquid PEG-4 Rapeseedamide solidifies at the temperature of approx. 0ᵒC.
"PEG" refers to a PEG-(polyethylene glycol-) derivative.

The number behind "PEG-" refers to the average number of molecular units -CH2-CH2-O-.
Ingredient on the basis of colza oil (brassica campestris seed oil).
Amides are generally conversion products of carbonic acids (carboxylic acids, mostly fatty acids) or other acids with nitrogen compounds (ammonia or alkyl and alkanol amines, amino acids etc).

Peg 4 rapeseedamide which shows very good solubilizing and emulsifying properties.
Peg 4 rapeseedamide presents better performance in terms of thickening and foaming than Cocamide DEA.
As of my last knowledge update in January 2022, I don't have specific information about "Peg 4 rapeseedamide.

Peg 4 rapeseedamide's possible that it's a chemical compound or a product ingredient, but without more context or updated information.
Peg 4 rapeseedamide could potentially refer to a compound derived from rapeseed oil.
Peg 4 rapeseedamide is obtained from the seeds of the rapeseed plant and is commonly used for various purposes, including cooking oil and industrial applications.

Peg 4 rapeseedamide is a polymer often used in the formulation of cosmetics, personal care products, and pharmaceuticals.
Explore online databases related to chemicals and compounds.
This might include databases from scientific organizations, chemical suppliers, or regulatory agencies.

Peg 4 rapeseedamide is a chemical used in industrial processes, contact chemical suppliers or manufacturers.
They might provide technical data sheets or other relevant information.
Search for recent articles or studies in scientific journals that discuss the properties, uses, or applications of Peg 4 rapeseedamide.

Some information about chemical compounds can be found in patent databases.
Search for patents related to Peg 4 rapeseedamide to understand its potential applications and properties.
Check chemical safety databases for any available information on the safety profile of Peg 4 rapeseedamide.

This could include data on toxicity, environmental impact, and regulatory status.
If possible, consult with experts in the field of chemistry, particularly those with expertise in surfactants, emulsifiers, or related compounds.
They may have insights into the nature and uses of Peg 4 rapeseedamide.

Boiling Point: 262°C
Melting Point: 7°C
Solubility: Dispersible in water

Due to its emulsifying properties, Peg 4 rapeseedamide acts as a co-emulsifier in O/W (oil-in-water) emulsions.
As an ingredient of an emulsion, it supports the other components responsible for generating the emulsion, which results from the formation of systems of two mutually insoluble phases.
Those phases are usually oil and water.

Due to the co-emulsifying effect of PEG-4 Rapeseedamide, emulsions are more stable and have the required consistency which facilitates their application.
As a surfactant, Peg 4 rapeseedamide is also a stabiliser and enhances the quality of foam in mixtures with anionic surfactants.
Emulsions are thermodynamic systems that are unstable by nature; therefore, it is necessary to use stabilisers such as PEG-4 Rapeseedamide.

The forces acting between the droplets of the dispersed phase may be strong enough to cause self-agglomeration of the dispersed phase particles, resulting in the separation of Peg 4 rapeseedamide e.g. a cream into layers.
This in turn will prevent its proper application.
The role of a surfactant is to create as large boundary surface areas as possible and to spread the dispersed phase particles.

PEG-4 Rapeseedamide is an ingredient of delicate products for washing the skin and hair.
Products that contain this surfactant have a reduced irritant potential and thus are designed for the care of especially sensitive areas.
Peg 4 rapeseedamide also has the thickening function in products.

Peg 4 rapeseedamide is purpose is to give the product the appropriate consistency.
Peg 4 rapeseedamide is effective both in preparations with an SLES (a strong surfactant) and in preparations without any surfactants.
Peg 4 rapeseedamide are poly condensation products of ethylene glycol, or polymerisation products of ethylene oxide.

The number added to the name refers to the mean number of ethylene oxide units in the Peg 4 rapeseedamide.
The consistency of the PEG derivatives is increasingly solid with a growing degree of polymerisation.
Peg 4 rapeseedamide with a mean molar mass of up to 600 g/mol are liquid, up to 1,000 g/mol wax-like and from 4,000 g/mol solid wax-like substances.

By mixing solid and liquid components, products of a creamy consistency are obtained which are used as water-free and water rinse-off bases.
With growing molar mass water solubility and hygroscopicity (ability to absorb moisture) of the polyethylene glycols decrease.
Peg 4 rapeseedamides and their derivates are preferentially used in cosmetic products since they have a broad spectrum of viscosity and solubility properties and have a very good skin tolerance.

As water soluble, non-greasy substances polyethylene glycols are suitable for many cosmetic purposes.
The liquid Peg 4 rapeseedamides serve, eg, as glycerol substitute in facial, shaving and hair lotions, as solubilisers and solvents.
Peg 4 rapeseedamide is an ingredient in a product, such as a cosmetic or personal care item, check the product label.

Ingredient lists are usually provided on the packaging.
Reach out to the manufacturer of the product containing Peg 4 rapeseedamide.
They should be able to provide detailed information about the Peg 4 rapeseedamide, its purpose in the product, and any safety considerations.

Search scientific databases, journals, or publications for any research or studies related to Peg 4 rapeseedamide.
Scientific literature might provide information on its properties, uses, and safety.
They may have information on the safety and regulations surrounding Peg 4 rapeseedamide.

Uses:
Peg 4 rapeseedamide derivatives are used in pharmaceuticals for drug delivery, solubilizing poorly water-soluble drugs, and as excipients in formulations.
Peg 4 rapeseedamide compounds are often found in cosmetics and personal care products as emulsifiers, surfactants, and thickeners.
They help to stabilize formulations and improve the texture of products like creams, lotions, and shampoos.

Peg 4 rapeseedamide derivatives can be used in industrial processes as lubricants, dispersants, and solvents.
Peg 4 rapeseedamide is used in the production of medical devices and diagnostics.
Peg 4 rapeseedamide compounds can be used as emulsifiers and stabilizers in certain food products.

Primesurf Peg 4 rapeseedamide is a component of detergents and personal care products like shampoos, shower gels, hand soaps and shaving gels.
Peg 4 rapeseedamide is a high performing and costeffective thickening agent.
Peg 4 rapeseedamide exhibits excellent thickening properties in various surfactant systems at low concentrations.

Peg 4 rapeseedamide also acts as a foam booster, strong solubilizer and emulsifier and is effective in both SLES-based and SLES-free formulations.
Peg 4 rapeseedamide is based on renewable rapeseed oil and shows good biodegradability.
Thanks to its liquid low viscosity concentrated form it is easy to handle and can also be formulated at room temperature.

Peg 4 rapeseedamide derivatives are used in pharmaceuticals for drug delivery, solubilizing poorly water-soluble drugs, and as excipients in formulations.
Peg 4 rapeseedamide compounds are often found in cosmetics and personal care products as emulsifiers, surfactants, and thickeners.
They help to stabilize formulations and improve the texture of products like creams, lotions, and shampoos.

Peg 4 rapeseedamide derivatives can be used in industrial processes as lubricants, dispersants, and solvents.
Peg 4 rapeseedamide is used in the production of medical devices and diagnostics.
Peg 4 rapeseedamide compounds can be used as emulsifiers and stabilizers in certain food products.

Reach out to the manufacturer or supplier of Peg 4 rapeseedamide.
They should be able to provide detailed information about the compound, its properties, and intended uses.
Contact information can often be found on product labels or the company's website.

Check any available product documentation, technical data sheets, or safety data sheets (SDS) for Peg 4 rapeseedamide.
These documents often contain information about the chemical composition, properties, and recommended uses.
Explore industry publications, journals, or articles related to the field in which Peg 4 rapeseedamide is used.

Sometimes, industry-specific literature can provide insights into the applications of certain compounds.
Check with regulatory agencies or databases relevant to the industry or application of Peg 4 rapeseedamide. These agencies might have information on approved uses, safety guidelines, and regulations.

Scientific Literature: Search for scientific literature and research papers that discuss Peg 4 rapeseedamide.
Academic journals and databases may provide information on its properties, synthesis, and potential applications.
Peg 4 rapeseedamide access to professional networks or industry associations, consider reaching out to experts in the field.

Networking with professionals who work with similar compounds could provide valuable insights.
Peg 4 rapeseedamide is used in commercial products, the manufacturer may provide technical data sheets.
These documents typically contain detailed information about the compound, including its properties, applications, and safety considerations.

Check relevant regulatory databases or agencies that oversee the use of chemicals in your industry or region.
They may have information on the approval status, safety, and permitted uses of Peg 4 rapeseedamide.

Search for recent scientific literature, research papers, or patents related to Peg 4 rapeseedamide.
Academic journals and patent databases can be valuable sources for understanding the properties and applications of chemical compounds.

Safety Profile:
PEG-4 Rapeseedamide is a safe ingredient and does not have any major side effects when used within the recommended guidelines.
Nonetheless, a patch test should be done prior to full application.
In cosmetic and personal care products, this ingredient can be added up to the concentration of 5%.

Additionally, Peg 4 rapeseedamide has a shelf life of up to two years when preserved properly.
Depending on the source of rapeseed oil used in the production of this ingredient, it can be vegan and halal.

Storage, Packaging and Handling:
Store in a tightly closed container in a roofed area, at a temperature up to 40°C.
Product storage in a temperature below 10°C can cause product turbidity which is not present influence on its properties.
After heating to room temperature, the product returns to its original form.

Synonyms:
PEG-4 RAPESEEDAMIDE
PEG-4 RAPESEEDAMIDE [INCI]
89575CN928
Amides, rape-oil, N-(hydroxyethyl), ethoxylated
85536-23-8
DTXSID201041786

cas no 9004-99-3 Poly(oxy-1,2-ethanediyl) .alpha.-(1-oxooctadecyl)-.omega.-hydroxy- (40 mol EO average molar ratio); polyoxyethylene (40) monostearate; polyethylene glycol (40) monostearate; Myrj 52;

DESCRIPTION:

PEG-40 stearate is a neutral surfactant.
PEG-40 stearate is a synthetic polymer composed of PEG (polyethylene glycol) and stearic acid, a naturally occurring fatty acid. Due to the presence of PEG, this ingredient may contain potentially toxic manufacturing impurities such as 1,4-dioxane.
In cosmetics and personal care products, PEG-40 stearates are used in skin creams, conditioners, shampoos, body cleansers. ,



CAS NUMBER: 9004-99-3

MOLECULAR FORMULA: (C2-H4-O)mult-.C18-H36-O2

MOLECULAR WEIGHT: 328.5



DESCRIPTION:

PEG-40 stearate is an octadecanoate ester composed of repeating 8-40 ethyleneoxy units.
PEG-40 stearate is an ingredient used in cosmetics and beauty products primarily as a surfactant and emulsifier.
PEG-40 stearate has a role as a non-ionic surfactant and an emulsifier.
PEG-40 stearate can be used as a thickener, texture enhancer, or to keep ingredients soluble in addition to its usual role as a cleansing agent in skin care formulas. PEG-40 stearate can be found in a wide range of skin care products, such as cleansers, creams, exfoliants, and serums.

PEG-40 Stearate works as an emulsifier, cleanser, surfactant, and humectant in cosmetics and personal care products.
PEG-40 stearates are soft to waxy solids that are white to tan in color.
In cosmetics and personal care products, PEG-40 stearates are used in skin creams, conditioners, shampoos, body cleansers and soapless detergents.
PEG-40 stearate also functions as a lubricant and antistatic agent.

PEG-40 stearate is used in dentifrices, creams, lotions, ointments, etc.
PEG-40 stearates clean the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away.
PEG-40 Stearate is an ester of polyethylene glycol and stearic acid. Stearic acid occurs naturally in many oils like palm and coconut oil.
The number with PEG-40 stearate denotes the number of monomer units attached in the chain.
PEG-40 Stearate is a white, waxy, or flaky solid.

PEG-40 stearate is an emulsifier for cosmetic O/W emulsions and is compatible with higher concentrations of electrolytes.
PEG-40 stearate acts as a solid lipophilic emulsifier.
PEG-40 stearate contains polyoxyethylene glycol fatty acid esters.
Its saponification value is 25-36.
PEG-40 stearate is an oily solid raw material with a density of 1.070 GR / CM3, in the form of solid oil, white in color and a characteristic odour.

PEG-40 stearate is widely used in the cosmetics and industrial sectors.
PEG-40 stearate is a good emulsifier.
For this purpose, PEG-40 stearate is used in hair care products, hair styling products, hand and face care creams and lotions.
PEG-40 stearate is manufactured by the polymerization of ethylene oxide (EO) with water, monoethylene glycol or diethylene glycol, under alkaline conditions.
PEG-40 stearate is manufactured by the ethoxylation of stearyl alcohol with the number of moles of ethylene oxide corresponding to the average polyethylene glycol chain length desired.

Impurities found in various PEGs and PEG derivatives may include residual ethylene oxide, 1,4-dioxane, polycyclic aromatic compounds, and heavy metals.
PEG-40 stearate is a mix of esters of stearic acid ethoxylated with approximately 40 units long polyoxyethylene glycols.
PEG-40 stearate's a multifunctional vegetable-based ingredient used primarily as a lipophilic non-ionic oil-in-water emulsifier (HLB value 17.3) and valuable as a humectant, dispersing agent, solubilizer, and surfactant.
PEG-40 stearate is a common ingredient in skin, hair, lip, and eye care formulas, thanks to increased stability even in sun care products.

PEG-40 Stearate fount its application in creams, masks, shampoos, and decorative cosmetics as a wetting agent.
Chemically inert with enhanced stability, PEG-40 stearate's suitable for a wide range of pH and actives, stabilizing emulsions, thickening, and improving skin feel.
PEG-40 stearate can be used as an excipient.
PEG-40 Stearate is an ester mixture of polyethylene glycol and stearic acid.
PEG-40 stearate is used to emulsify solvents in cosmetic formulas, can contribute to improved product texture, and in larger quantities it can also be a cleaning agent.

PEG-40 Stearate can be animal-derived or synthetic; LNDA uses only synthetic form.
PEG-40 stearate is one of the many PEG compounds that are considered safe as used in cosmetics.
PEG-40 stearate is a synthetic polymer composed of PEG (polyethylene glycol) and stearic acid, a naturally occurring fatty acid.
PEG-40 stearate is a synthetic polymer composed of PEG (polyethylene glycol) and stearic acid, a naturally occurring fatty acid.used in skin care.
PEG-40-Stearate cleans the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away and therefore it is used in shampoos.

As PEG-40 stearate also has emollient properties it is used hair conditioners and masks.
PEG-40 Stearate may or may not be vegan.
PEG-40 stearate is a PEG compound of Stearic Acid, used in cosmetics as an emulsifier.
PEG-40 stearate is a mixture of polyethylene glycol esters.
PEG-40 stearate is compatible with lipophilic compounds due to a higher free fatty acid content.

PEG-40 stearate is a high molecular weight, high HLB surface active agent suggested for use in cosmetic formulations (emulsifier, viscosity modifier) and in lubricants (emulsifier).
PEG-40 stearate is a multifunctional surface active agent suggested for use in cosmetic formulations, household products, lubricants, textile chemicals, polishes and paper.
PEG-40 Stearate is a chemical compound commonly used in the cosmetics and personal care industry.
PEG-40 stearate is an ingredient that can be found in various skincare, haircare, and cosmetic products, such as creams, lotions, cleansers, and makeup.

PEG-40 stearate stands for Polyethylene Glycol, which is a synthetic polymer made from ethylene oxide.
Stearate refers to the stearic acid ester of PEG-40 stearate.
Essentially, PEG-40 Stearate is a combination of a polyethylene glycol chain and stearic acid.
PEG-40 Stearate serves as an emulsifier and surfactant in cosmetic formulations.
Emulsifiers help mix oil and water-based ingredients in products, preventing them from separating.
Surfactants, on the other hand, help to reduce the surface tension between different substances, making it easier for them to mix together.

In skincare products, PEG-40 Stearate helps create stable emulsions, allowing oil and water-based ingredients to form consistent formulations.
PEG-40 stearate also contributes to the texture and feel of the product, improving its spreadability and overall application.
Additionally, PEG-40 Stearate can enhance the solubility of certain ingredients in water-based solutions.
PEG-40 stearate's important to note that while PEG-40 Stearate is widely used in the cosmetics industry, there have been concerns about certain PEG compounds potentially being contaminated with harmful impurities, such as 1,4-dioxane, which is considered a potential human carcinogen.
Manufacturers often take steps to purify PEG-40 stearate compounds to minimize the presence of such impurities, and regulatory bodies may set limits on their use to ensure consumer safety.



APPLICATION:

PEG-40 stearate has been used in a study to assess the phase behaviors of special hot microemulsion to produce drug-loaded nanostructured lipid carriers.
PEG-40 stearate has also been used in a study to investigate its effects on multidrug resistance (MDR).



USES:

-surfactant
-emulsifier (cosmetics, pharmaceuticals, textile finishes, defoamers, and baked goods)
-dye assistant
-lubricant
-antistatic agent
-dentifrice compositions



USAGE AREAS:

-Cosmetics
-Pharmaceuticals
-Inks & Coatings



FEATURES:

-Cleansing
-Emulsifying
-Surfactant



SPECIFICATIONS:

-Molecular Weight: 328.5
-Molecular Formula: HO(CH2CH2O)nOCC17H35
-Canonical SMILES: CCCCCCCCCCCCCCCCCC(=O)OCCO
-InChI: InChI=1S/C20H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)23-19-18-21/h21H,2-19H2,1H3
-InChIKey: RFVNOJDQRGSOEL-UHFFFAOYSA-N
-Boiling Point: 438.00 to 439.00 °C at 760.00 mm Hg (est)
-Melting Point: 47°C
-Flash Point: 39°C
-Density: 0.913 g/cm³
-Solubility: POLYETHYLENE GLYCOL ESTERS AND ETHERS INCR THE WATER SOLUBILITY OF TYROTHRICIN
-Appearance: Light amber semiSolid
-Assay: 0.99
-Log P: 7.629 (est)
-Stability: Stable.



PHYSICAL AND CHEMICAL PROPERTIES:

-Melting point: 47 °C
-Fp: 39 °C
-storage temp.: 2-8°C
-Water Solubility: Soluble in water
-solubility: Chloroform (Slighty), Methanol (Slightly)
-form: powder to lump
-color: White to Almost white
-Odor: at 100.00?%. mild fatty
-Hydrophilic-Lipophilic Balance (HLB): 18.8
-LogP: 7.629 (est)



PROPERTIES:

-description: non-ionic
-form: powder
-application(s): detection
-InChI: 1S/C20H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)23-19-18-21/h21H,2-19H2,1H3
-InChI key: RFVNOJDQRGSOEL-UHFFFAOYSA-N



PHYSICAL PROPERTIES:

-Assay: 95.00 to 100.00
-Boiling Point: 438.00 to 439.00 °C. @ 760.00 mm Hg (est)
-Flash Point: 328.00 °F. TCC ( 164.60 °C. ) (est)
-logP (o/w): 7.629 (est)



PROPERTIES:

-Odor Strength: none
-Odor Description: at 100.00 %. mild fatty
-Taste Description: bitter fatty



FUNCTIONS:

-Emulsifying agent: Promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil)
-Surfactant: Reduces the surface tension of cosmetics and contributes to the even distribution of the product during use



PRODUCT INFORMATIONS:

-Usage/Application: Personal Care
-Form: Pellets
-Dosage: 2.0 to 3.0%
-CAS Number: 9004-99-3
-Color: White



STORAGE:

Keep tightly closed in a cool place in a tightly closed container.



SYNONYM:

Peg-40 glyceryl stearate
0A0VSM3HAD
EMALEX GM-40
GLYCERETH-40 STEARATE
POLYETHYLENE GLYCOL (40) GLYCERYL STEARATE
POLYOXYETHYLENE (40) GLYCERYL STEARATE
POLYOXYL 40 GLYCERYL STEARATE
2-Hydroxyethyl stearate
Ethylene glycol monostearate
Glycol stearate
2-Hydroxyethyl octadecanoate
Cremophor A
Glycol monostearate
Monthybase
Parastarin
Monthyle
Sedetol
Ivorit
Prodhybase ethyl
Prodhybas N
Cerasynt M
Clearate G
Cerasynt MN
Cithrol PS
Clindrol SEG
OCTADECANOIC ACID, 2-HYDROXYETHYL ESTER
Lipo EGMS
Cithrol 10MS
Lactine
Cerasynt 660
Myrj
Tego-stearate
Akyporox S 100
Prodhybase P
PEG stearate
Emerest 2350
Emerest 2640
Empilan 2848
Lamacit CA
Soromin-SG

PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) Polyethylene Glycol (PEG) Stearates (PEG-2 Stearate, PEG-6 Stearate, PEG-8 Stearate, PEG-12 Stearate, PEG-20 Stearate, PEG-32 Stearate, PEG-40 Stearate, PEG-50 Stearate, PEG-100 Stearate, PEG-150 Stearate) are esters of polyethylene glycol and stearic acid. The PEG Stearates are soft to waxy solids that are white to tan in color. In cosmetics and personal care products, PEG Stearates are used in skin creams, conditioners, shampoos, body cleansers and soapless detergents. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) is used in cosmetics and beauty products primarily as a surfactant and cleansing agent, because PEG Stearates' ability to clean the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away, according to. However, it is also seen as an emollient, because of secondary properties. * A surfactant and cleansing agent * Please read TIA’s article on What Is PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate): PEGs Functions of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate): PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) is used in cosmetics and beauty products primarily as a surfactant and cleansing agent, because PEG Stearates' ability to clean the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away, according to CosmeticsInfo.org. However, it is also seen as an emollient, because of secondary properties. Unlike typical PEGs, (whose identifying number corresponds to their molecular weight) the numerical value of each PEG Stearate corresponds to the average number of ethylene oxide monomers in the polyethylene chain (from 2 - 150). Despite the many fears regarding PEGs, they are seen as an ingredient in a large number of products because of their diverse properties. In a study published in the Toxicology journal in 2005, entitled "Safety assessment on polyethylene glycols (PEGs) and their derivatives as used in cosmetic products," it was concluded that: "Taking into consideration all available information from related compounds, as well as the mode and mechanism of action, no safety concern with regard to these endpoints could be identified. Based on the available data it is therefore concluded that PEGs of a wide molecular weight range (200 to over 10,000), their ethers (laureths. ceteths, ceteareths, steareths, and oleths), and fatty acid esters (laurates, dilaurates, stearates, distearates) are safe for use in cosmetics." PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) is not considered to be an irritant or sensitizer (it gave only minimal irritation in studies up to 100%), and are CIR and FDA approved for use, but not on broken skin (Source). Safety Measures/Side Effects of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE): However. The Cosmetics Database found PEG 40 Stearate to be a moderate to high hazard ingredient depending on usage. The EWG issues warnings regarding: cancer, developmental and reproductive toxicity, contamination concerns, irritation, and organ system toxicity. According to a study published in the International Journal of Toxicology, PEGs (including PEG 40 Stearate) can contain harmful impurities, including: Ethylene Oxide, known to increase the incidences of uterine and breast cancers and of leukemia and brain cancer, according to experimental results reported by the National Toxicology Program; 1,4-dioxane, a known carcinogen; PAHs, known to increase the risk of breast cancer; lead; iron; and arsenic (Source). Products and formulas containing PEG 40 Stearate should not be used on broken or irritated skin. Although PEGs are considered safe for use topically on healthy skin, studies showed that patients suffering from severe burns were treated with PEG-based antimicrobial cream; this treatment resulted in kidney toxicity. "The PEG content of the antimicrobial cream was determined to be the causative agent. However, no evidence of systemic toxicity occurred in studies with intact skin. Because of the observation of kidney effects in burn patients, the CIR Expert Panel qualified their conclusion on the safety of the PEG ingredients to state that cosmetic formulations containing these ingredients should not be used on damaged skin" SYNONYMS of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) Polyoxyl (40) stearate, polyoxyethylene (40) monostearate; INS No. 431 DEFINITION Consists of a mixture of the mono- and diesters of edible commercial stearic acid and mixed polyoxyethylene diols (having an average polymer length of about 40 oxyethylene units) together with free polyol. Structural formula Nominal formula and approximate composition: free polyol monoester diester where RCO- is a fatty acid moiety, and "n" has an average value of approximately 40. The distribution of polymers is approximately in accordance with the Poisson expression. Assay Not less than 84.0 and not more than 88.0% of oxyethylene groups equivalent to not less than 97.5 and not more than 102.5% of polyoxyethylene (40) stearate calculated on the anhydrous basis. DESCRIPTION of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) Cream-coloured and exists as flakes or as a waxy solid at 25o with a faint odour FUNCTIONAL USESEmulsifier of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) CHARACTERISTICS of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) IDENTIFICATION of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) Solubility (Vol. 4) Soluble in water, ethanol, methanol and ethylacetate; insoluble in mineral oil Congealing range (Vol. 4)39 - 44o Infrared absorption The infrared spectrum of the sample is characteristic of a partial fatty acid ester of a polyoxyethylated polyol Colour reaction To 5 ml of a 5% (w/v) aqueous solution of the sample add 10 ml of ammonium cobaltothiocyanate solution and 5 ml of chloroform, shake well and allow to separate; a blue colour is produced in the chloroform layer. (Ammonium cobaltothiocyanate solution: 37.5 g of cobalt nitrate and 150 g of ammonium thiocyanate made up to 100 ml with water - freshly prepared). Saponification (Vol. 4) 100 g of the sample yields approximately 13-14 g of fatty acids and 85-87 g of polyols PURITY of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) Water (Vol. 4) Not more than 3% (Karl Fischer Method) Acid value (Vol. 4) Not more than 1 Saponification value (Vol. 4) Not less than 25 and not more than 35 Hydroxyl value (Vol. 4) Not less than 27 and not more than 40 Lead (Vol. 4) Not more than 2 mg/kg Determine using an atomic absorption technique appropriate to the specified level. The selection of sample size and method of sample preparation may be based on the principles of the method described in Volume 4, “Instrumental Methods.” METHOD OF ASSAY of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) Determine the content of Oxyethylene groups. Polyoxyethylene (40) stearate has been used in a study to assess the phase behaviors of special hot microemulsion to produce drug-loaded nanostructured lipid carriers. [3] It has also been used in a study to investigate its effects on multidrug resistance (MDR). Polyoxyethylene 40 monostearate, also known as ethylene glycol monostearate or myrj 52, belongs to the class of organic compounds known as fatty acid esters. These are carboxylic ester derivatives of a fatty acid. Polyoxyethylene 40 monostearate is considered to be a practically insoluble (in water) and relatively neutral molecule. Polyoxyethylene 40 monostearate has been primarily detected in urine. Within the cell, polyoxyethylene 40 monostearate is primarily located in the membrane (predicted from logP) and cytoplasm. A sample work-up method for gas chromatographic profiling of polyethylene glycol related cmpd in pharmaceutical matrixes is described. After a short sample clean-up, carbon-oxygen linkages were partially cleaved with 0.07/M BBr3 in CH2Cl2 at room temp. The reaction was stopped after 1 min by addn of 0.01M hydrochloric acid. The products were trimethylsilylated and injected onto a WCOT 50 m X 0.25 mm CP-SIL 5 CB fused silica column. Eleven model cmpd, representing 4 common types of polyethylene glycol deriv, were evaluated by this method. Characteristic profiles can be obtained from polyethylene glycol deriv carrying different functional groups. Minimum detectable amt are in the range of 200 ug. Polyoxyl 40 Stearate is used in cosmetics and beauty products primarily as a surfactant and emulsifier. It occurs naturally as a white, waxy or flaky substance, according to The Food and Agriculture Organization of the United Nations. CosmeticsInfo.org notes that Polyoxyl 40 Stearate, as part of the PEG Stearate group, are formed from a naturally fatty acid known as Stearic Acid. The PEG Sterates are used in cosmetics and skin care formulas because they can "clean the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away. Polyethylene glycol (PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate); /ˌpɒliˈɛθəlˌiːn ˈɡlaɪˌkɒl, -ˌkɔːl/) is a polyether compound with many applications, from industrial manufacturing to medicine. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight. The structure of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is commonly expressed as H−(O−CH2−CH2)n−OH.[3] Contents 1 Uses of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) 1.1 Medical uses of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) 1.2 Chemical uses of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) 1.3 Biological uses of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) 1.4 Commercial uses of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) 1.5 Industrial uses of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) 1.6 Recreational uses of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) 2 Health effects of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) 3 Available forms and nomenclature of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) 4 Production of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) Uses of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) Medical uses of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is the basis of a number of laxatives.[4] Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is also used as an excipient in many pharmaceutical products. When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood.[5] The possibility that PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) could be used to fuse axons is being explored by researchers studying peripheral nerve and spinal cord injury.[4] Chemical uses of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) The remains of the 16th century carrack Mary Rose undergoing conservation treatment with PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) in the 1980s Terra cotta warrior, showing traces of original color Because PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is a hydrophilic molecule, it has been used to passivate microscope glass slides for avoiding non-specific sticking of proteins in single-molecule fluorescence studies.[6] Polyethylene glycol has a low toxicity and is used in a variety of products.[7] The polymer is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments.[8] Since PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures (on the order of tens of atmospheres). It also is unlikely to have specific interactions with biological chemicals. These properties make PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) one of the most useful molecules for applying osmotic pressure in biochemistry and biomembranes experiments, in particular when using the osmotic stress technique. Polyethylene glycol is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) has also been used to preserve objects that have been salvaged from underwater, as was the case with the warship Vasa in Stockholm,[9] and similar cases. It replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.[4] In addition, PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is used when working with green wood as a stabilizer, and to prevent shrinkage.[10] PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China.[11] These painted artifacts were created during the Qin Shi Huang (first emperor of China) era. Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xi'an air. The paint would subsequently flake off in about four minutes. The German Bavarian State Conservation Office developed a PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.[12] PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) derivatives, such as narrow range ethoxylates, are used as surfactants. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.[13] PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) has also been used as a propellent on the UGM-133M Trident II Missile, in service with the United States Air Force.[14] Biological uses PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.[6] PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is commonly used as a precipitant for plasmid DNA isolation and protein crystallization. X-ray diffraction of protein crystals can reveal the atomic structure of the proteins. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas. César Milstein and Georges J. F. Köhler originated this technique, which they used for antibody production, winning a Nobel Prize in Physiology or Medicine in 1984.[4] Polymer segments derived from PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) polyols impart flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam cushions. In microbiology, PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) precipitation is used to concentrate viruses. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro. Gene therapy vectors (such as viruses) can be PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate)-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect.[15] The size of the PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) polymer has been shown to be important, with larger polymers achieving the best immune protection. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is a component of stable nucleic acid lipid particles (SNALPs) used to package siRNA for use in vivo.[16][17] In blood banking, PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is used as a potentiator to enhance detection of antigens and antibodies.[4][18] When working with phenol in a laboratory situation, PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) 300 can be used on phenol skin burns to deactivate any residual phenol (some references are required). In biophysics, polyethylene glycols are the molecules of choice for the functioning ion channels diameter studies, because in aqueous solutions they have a spherical shape and can block ion channel conductance.[19][20] Commercial uses of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is the basis of many skin creams (as cetomacrogol) and personal lubricants (frequently combined with glycerin). PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is used in a number of toothpastes[4] as a dispersant. In this application, it binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is also under investigation for use in body armor, and in tattoos to monitor diabetes.[21][22] In low-molecular-weight formulations (e.g. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) 400), it is used in Hewlett-Packard designjet printers as an ink solvent and lubricant for the print heads. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is also used as an anti-foaming agent in food and drinks[23] – its INS number is 1521[24] or E1521 in the EU.[25] Industrial uses of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) A nitrate ester-plasticized polyethylene glycol (NEPE-75) is used in Trident II submarine-launched ballistic missile solid rocket fuel.[26] Dimethyl ethers of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) are the key ingredient of Selexol, a solvent used by coal-burning, integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the gas waste stream. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.[27] PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is also used as a polymer host for solid polymer electrolytes. Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate), with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is injected into industrial processes to reduce foaming in separation equipment. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is used as a binder in the preparation of technical ceramics.[28] Recreational uses of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is used to extend the size and durability of very large soap bubbles. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is the main ingredient in many personal lubricants. Health effects of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is considered biologically inert and safe by the FDA. However, a growing body of evidence shows the existence of anti PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) antibodies in approximately 72% of the population based on plasma samples from 1990–1999.[medical citation needed] The FDA has been asked to investigate the possible effects of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) in laxatives for children.[29] Due to its ubiquity in a multitude of products and the large percentage of the population with antibodies to PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate), hypersensitive reactions to PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) are an increasing concern.[medical citation needed] Allergy to PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is usually discovered after a person has been diagnosed with an allergy to an increasing number of seemingly unrelated products, including processed foods, cosmetics, drugs, and other substances that contain PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) or were manufactured with PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate).[30] When PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is chemically attached to therapeutic molecules (such as protein drugs or nanoparticles), it can sometimes be antigenic, stimulating an anti-PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) antibody response in some patients. This effect has only been shown for a few of the many available PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate)ylated therapeutics, but it has significant effects on clinical outcomes of affected patients.[31] Other than these few instances where patients have anti-PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) immune responses, it is generally considered to be a safe component of drug formulations. Available forms and nomenclature of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate), PEO, and POE refer to an oligomer or polymer of ethylene oxide. The three names are chemically synonymous, but historically PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is preferred in the biomedical field, whereas PEO is more prevalent in the field of polymer chemistry. Because different applications require different polymer chain lengths, PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) has tended to refer to oligomers and polymers with a molecular mass below 20,000 g/mol, PEO to polymers with a molecular mass above 20,000 g/mol, and POE to a polymer of any molecular mass.[32] PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate)s are prepared by polymerization of ethylene oxide and are commercially available over a wide range of molecular weights from 300 g/mol to 10,000,000 g/mol.[33] PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) and PEO are liquids or low-melting solids, depending on their molecular weights. While PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) and PEO with different molecular weights find use in different applications, and have different physical properties (e.g. viscosity) due to chain length effects, their chemical properties are nearly identical. Different forms of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) are also available, depending on the initiator used for the polymerization process – the most common initiator is a monofunctional methyl ether PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate), or methoxypoly(ethylene glycol), abbreviated mPEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate). Lower-molecular-weight PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate)s are also available as purer oligomers, referred to as monodisperse, uniform, or discrete. Very high purity PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) has recently been shown to be crystalline, allowing determination of a crystal structure by x-ray diffraction.[33] Since purification and separation of pure oligomers is difficult, the price for this type of quality is often 10–1000 fold that of polydisperse PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate). PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate)s are also available with different geometries. Branched PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate)s have three to ten PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) chains emanating from a central core group. Star PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate)s have 10 to 100 PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) chains emanating from a central core group. Comb PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate)s have multiple PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) chains normally grafted onto a polymer backbone. The numbers that are often included in the names of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate)s indicate their average molecular weights (e.g. a PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) with n = 9 would have an average molecular weight of approximately 400 daltons, and would be labeled PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) 400.) Most PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate)s include molecules with a distribution of molecular weights (i.e. they are polydisperse). The size distribution can be characterized statistically by its weight average molecular weight (Mw) and its number average molecular weight (Mn), the ratio of which is called the polydispersity index (Mw/Mn). Mw and Mn can be measured by mass spectrometry. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate)ylation is the act of covalently coupling a PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) structure to another larger molecule, for example, a therapeutic protein, which is then referred to as a PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate)ylated protein. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate)ylated interferon alfa-2a or −2b are commonly used injectable treatments for hepatitis C infection. PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is soluble in water, methanol, ethanol, acetonitrile, benzene, and dichloromethane, and is insoluble in diethyl ether and hexane. It is coupled to hydrophobic molecules to produce non-ionic surfactants.[34] PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate)s potentially contain toxic impurities, such as ethylene oxide and 1,4-dioxane.[35] Ethylene Glycol and its ethers are nephrotoxic if applied to damaged skin.[36] Polyethylene oxide (PEO, Mw 4 kDa) nanometric crystallites (4 nm) Polyethylene glycol (PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate)) and related polymers (PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) phospholipid constructs) are often sonicated when used in biomedical applications. However, as reported by Murali et al., PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) is very sensitive to sonolytic degradation and PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) degradation products can be toxic to mammalian cells. It is, thus, imperative to assess potential PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) degradation to ensure that the final material does not contain undocumented contaminants that can introduce artifacts into experimental results.[37] PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate)s and methoxypolyethylene glycols are manufactured by Dow Chemical under the tradename Carbowax for industrial use, and Carbowax Sentry for food and pharmaceutical use. They vary in consistency from liquid to solid, depending on the molecular weight, as indicated by a number following the name. They are used commercially in numerous applications, including as surfactants, in foods, in cosmetics, in pharmaceutics, in biomedicine, as dispersing agents, as solvents, in ointments, in suppository bases, as tablet excipients, and as laxatives. Some specific groups are lauromacrogols, nonoxynols, octoxynols, and poloxamers. Macrogol, used as a laxative, is a form of polyethylene glycol. The name may be followed by a number which represents the average molecular weight (e.g. macrogol 3350, macrogol 4000 or macrogol 6000). Production of PEG 40 STEARATE (POLYOXYETHYLENE 40 STEARATE) (Polioksietilen 40 stearat) (Polyoxyl 40 stearate) Polyethylene glycol 40, pharmaceutical quality Polyethylene glyco

PEG 400 Monostearate is a white solid.
PEG 400 Monostearate is an ingredient used in cosmetics and beauty products primarily as a surfactant and emulsifier.


CAS Number: 9004-99-3
EC Number: 618-405-1
MDL Number: MFCD00148007
Chemical Formula: C20H40O3 / HO(CH2CH2O)nOCC17H35
Molecular Formula: C20H40O3



Polyoxyethylene stearate,Polyoxyl stearate, PEG-8 Stearate, Myrj 45, Polyoxyethylene Monostearate ester, POE(9) Monostearate, PEG 400 monostearate, PEG400 monostearate, Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy-, Myrj* 45, PEG-8 Stearate, PEG 400 Monostearate, Unipeg 400M, JEEN T/N: Jeemate 400-DPS, PEG-8 Stearate, Polyglycol monostearate, Poly(oxy-1,2-ethanediyl),α-(1-oxooctadecyl)-ω-hydroxy-, Glycols,polyethylene,monostearate, Stearic acid,monoester with polyethylene glycol, Nonex 28, Nonex 29, PEG 42, Myrj 45, Myrj 49, Myrj 51, Myrj 52, Myrj 53, Nonex 53, Nonex 54, Nonex 63, X 489R, S 541, S 1012, S 1054, S 1116, Atlox 5000, Cerasynt M, Cerasynt MN, Cithrol PS, Clearate G, Crill 20, Emcol H 35A, Empilan CP 100, Empilan CQ 100, Kessco X 211, Lactine, Lipal 15S, Macrogol stearate 400, PEG 600 monostearate, PEG 1000 monostearate, Perphinol 45/100, Polyethylene glycol 200 monostearate, Polyethylene glycol 4000 monostearate, Polyethylene glycol 300 monostearate, Polyethylene glycol monostearate, Polyethylene glycol 400 monostearate, Polyethylene glycol 400 stearate, Polyethylene glycol 1540 stearate, Polyethylene glycol 3000 monostearate, Polystate, Prodhybase P, Prodhybase 4000, Soromin SG, Stabilisant Delta 118, Ethofat 60/25, Polystate B, Poly(oxyethylene) stearate, Polyethylene glycol stearate, Myrj 52S, Stearox 6, Myrj, Myrj 59, Nikkol MYS 45, PEG stearate, Stearic acid-ethylene oxide adduct, Ethofat 60/20, Ethofat 60/15, Polyethylene oxide monostearate, S 1004, S 1016, S 1042, Carbowax 1000 monostearate, Carbowax 1500 monostearate, Poly(ethyleneoxy)monostearate, Poly(oxyethylene) monostearate, Nonion S 15, Polyethylene glycol 40 monostearate, LX 3, Poly(oxyethylene) stearic acid ester, PEG 600MS, PEG 100MS, PEG 1000MS, Cithrol 10MS, Nissan Nonion S 15, Emery 15393, Nikkol MYS 40, 8035-96-9, 8050-55-3, 9009-90-9, 11107-94-1, 11108-48-8, 35885-17-7, 39404-30-3, 42610-76-4, 52504-21-9, 52504-22-0, 52504-23-1, 53228-13-0, 53335-42-5, 55247-85-3, 58375-39-6, 63654-37-5, 72993-78-3, 74870-86-3, 86473-52-1, 121340-91-8, 123543-87-3, 939018-14-1, 1436689-96-1, 1887122-60-2, 1887123-58-1, 2143941-58-4, Ethylene glycol monostearate, 2-Hydroxyethyl stearate, Glycol stearate, 9004-99-3, 111-60-4, 2-Hydroxyethyl octadecanoate, Cremophor A, Glycol monostearate, Monthybase, Parastarin, Monthyle, Sedetol, Ivorit, Prodhybase ethyl, Prodhybas N, Cerasynt M, Clearate G, Cerasynt MN, Cithrol PS, Clindrol SEG, OCTADECANOIC ACID, 2-HYDROXYETHYL ESTER, Lipo EGMS, PEG-8 Stearate, Cithrol 10MS, PEG-40 stearate, Lactine, Cerasynt 660, Myrj, Tego-stearate, Akyporox S 100, Prodhybase P, PEG stearate, Emerest 2350, Emerest 2640, Empilan 2848, Lamacit CA, Soromin-SG, Emanon 3113, Myrj 45, Stearoks 6, Stearoxa-6, Nikkol MYS, Ethylene glycol stearate, Pegosperse S 9, Stearox 6, Emcol H 35-A, Arosurf 1855E40, Stenol 8, Prodhybase 4000, Stearoks 920, Nikkol MYS 4, Nonion S 2, Nonion S 4, Nissan Nonion S-2, Stearox 920, Lipal 15S, Nonex 28, Nonex 29, Nonex 36, Nonex 53, Nonex 54, Nonex 63, PEG-150 stearate, Lipo-Peg 4-S, Nikkol MYS 40, Nikkol MYS 45, Nikkol MYS-25, Nonion S 15, Trydet SA 40, Empilan CP-100, Empilan CQ-100, Nissan Nonion S 15, Myrj 52S, Kessco X-211, Emunon 3115, Ethofat 60/15, Ethofat 60/20, Ethofat 60/25, Myrj 51, Myrj 53, Perphinol 45/100, Lipal 400-S, STEARIC ACID, 2-HYDROXYETHYL ESTER, Tegin G, Ionet MS-1000, Emery 15393, Glycol stearate SE, USAF KE-11, Ethylene glycol, monostearate, MYRJ 49, MYRJ 52, PEG 100MS PEG 600MS, Myrj 59, Stearic acid, monoester with ethylene glycol, Ethylene glycol monostearate SE, Glycol monostearate SE, Macrogol ester (INN), S 151, Myrj 52 (TN), 86418-55-5, DTXSID5026881, NSC31811, 0324G66D0E, NCGC00188435-01, Trydet SA series, PEG-10 Stearate, Slovasol MKS 16, Usaf ke-9, Emulphor VT-650, Usaf ke-12, Usaf ke-14, Poly(oxy-1,2-ethanediyl), a-(1-oxooctadecyl)-w-hydroxy-, Magi 45, Emanon 3199, Stabilisant delta-118, PMS No. 1, PMS No. 2, LX 3, MYS 40, MYS 45, PEG 1000MS, PEG 42, UNII-6YLY96TQL6, X-489-R, Macrogol ester, S 541, Schercemol EGMS, Alkamuls SEG, Ablunol EGMS, S 1004, S 1012, S 1054, S 1116, Alkamuls EGMS/C, PEG40 stearate, EINECS 203-886-9, Pegosperse 50 MS, MFCD00051465, Glycols, monostearate, BRN 1794033, Cerasynt M (Salt/Mix), ethyleneglycol monostearate, Cerasynt MN (Salt/Mix), Peg 2000 ms, Stabilisant .delta.-118, 6YLY96TQL6, SCHEMBL10412, GLYCOL STEARATE [II], Crill 20,22,23, GLYCOL STEARATE [INCI], n inverted exclamation markO10, DTXCID006881, GLYCOL STEARATE [VANDF], CHEMBL2355383, UNII-0324G66D0E, CHEBI:32027, CHEBI:167626, 17-Hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl octadecanoate, Crill 20,21,22, 23, Tox21_113036, NSC-31811, AKOS015843173, octadecanoic acid 2-hydroxyethyl ester, BS-48654, CAS-111-60-4, CS-0440899, ETHYLENE GLYCOL MONOSTEARATE [WHO-DD], FT-0626337, N,N-BIS-(1-PHENYL-ETHYL)-MALONAMIDE, NS00007971, D01542, F71203, F71256, L001305, Q5572621, W-109413, Poly(oxy-1,2-ethanediyl), α-(1-oxooctadecyl)-ω-hydroxy-, Glycols, polyethylene, monostearate, Stearic acid, monoester with polyethylene glycol, Nonex 28, Nonex 29, PEG 42, Myrj 45, Myrj 49, Myrj 51, Myrj 52, Myrj 53, Nonex 53, Nonex 54, Nonex 63, X 489R, S 541, S 1012, S 1054, S 1116, Atlox 5000, Cerasynt M, Cerasynt MN, Cithrol PS, Clearate G, Crill 20, Emcol H 35A, Empilan CP 100, Empilan CQ 100, Kessco X 211, Lactine, Lipal 15S, Macrogol stearate 400, PEG 600 monostearate, PEG 1000 monostearate, Perphinol 45/100, Polyethylene glycol 200 monostearate, Polyethylene glycol 4000 monostearate, Polyethylene glycol 300 monostearate, Polyethylene glycol monostearate, Polyethylene glycol 400 monostearate, Polyethylene glycol 400 stearate, Polyethylene glycol 1540 stearate, Polyethylene glycol 3000 monostearate, Polystate, Prodhybase P, Prodhybase 4000, Soromin SG, Stabilisant Delta 118, Ethofat 60/25, Polystate B, Poly(oxyethylene) stearate, Polyethylene glycol stearate, Myrj 52S, Stearox 6, Myrj, Myrj 59, Nikkol MYS 45, PEG stearate, Stearic acid-ethylene oxide adduct, Ethofat 60/20, Ethofat 60/15, Polyethylene oxide monostearate, S 1004, S 1016, S 1042, Carbowax 1000 monostearate, Carbowax 1500 monostearate, Poly(ethyleneoxy)monostearate, Poly(oxyethylene) monostearate, Nonion S 15, Polyethylene glycol 40 monostearate, LX 3, Poly(oxyethylene) stearic acid ester, PEG 600MS, PEG 100MS, PEG 1000MS, Cithrol 10MS, Nissan Nonion S 15, Emery 15393, Nikkol MYS 40, Nikkol MYS 4, Nonex 36, Stearox 920, Nissan Nonion S 2, Ionet MS 1000, Lamacit CA, Nonion S 2, Nikkol MYS 25, Emanon 3115, PEG 40 Stearate, Pegosperse S 9, PEG 8 Stearate, PEG 150 Stearate, Cerasynt 660, Polyethylene glycol 100 monostearate, Emerest 2640, Polyoxyl 40 Stearate, Lipal 400S, Carbowax 4000 monostearate, 40S, 60S, Akyporox S 100, MYS 40, Emanon 3113, Trydet SA 40, Arosurf 1855E40, MYS 45, Nikkol MYS, Nissan Nonion S 4, Emanon 3199, Slovasol MKS 16, Cithrol 4MS, Simulsol M 59, Simulsol M 52, Simulsol M 49, Simulsol M 45, Simulsol M 51, Simulsol M 53, Simulsol M, Teric SF 15, Nikkol MYS 10, Teric SF, Ropol 24, Rokacet S 10, Crill 22, Crill 23, Crill 21, Polyoxyl 8 stearate, Varonic 1000MS, Polynon S 44, Varonic 1800MS, Cremofor 410R, Nikkol MYS 55, Nonion S 4, Verox S 12, Verox S 16, Verox S 18, G 2159, Tegester PEG, Emalex 804, Lipal 400MS, Polynon S 66, Eumulgin ST 8, Nissan Nonion S 15.4, Nonion s 15.4, Emanon 3119, Nissan Nonion S 40, Nissan Nonion S 10, Rokacet S 17, Monestriol 104, Monestriol 102, Nissan Nonion S 30, MYS 4, Alkasurf S 65-8, Polyethoxy-50-stearate, Polyethoxylated monostearate, Cremophor 410R, Ionet MS 400, Crodet S 24, Crodet S, Nonion S 6, Nissan Nonion S 6, Pegosperse 100S, Pegosperse 50MS, Lipopeg 100S, Lipopeg 39S, Lipopeg 4S, MYS 2, MYS 10, Cremophor S 9, Mapeg S 40K, Chemax E 400MS, Hodag 150S, Polyethylene glycol monostearic acid ester, Nonio-light S 100, Nikkol MYS 2, PEG-40M, Nikkol MYS 1EX, SG 6 (surfactant), SG 6, Capcure 65, Stearic acid-ethylene oxide condensate, Octadecanoic acid-oxirane copolymer, Oxirane-octadecanoic acid copolymer, Oxirane-stearic acid copolymer, Mapeg 600MS, Pegosperse 400MS, Witconol 2711, Crodet S 100, Unipeg 200MS, Ethoxylated stearic acid, SDH 4E, Emerest 2662, 40S (polyether), 60S (polyether), Mapeg 400MS, Ionet MS 600, Pegnol 14S, Chemax E 1750MS, Emanon 3170, Rokacet S 2, Rokacet S 8, Rokacet S 24, Serdox NSG 600, Serdox NSG 200, Serdox NSG 400, YMS 2, Emerest 2715, Macrogol stearate, Emalex 6300M-ST, Nonion S 40, Nonion S 10, Leveler 528, Myrj 52P, Myrj 49P, Marlosol 1820, Cerasynt 840, Kessco PEG 6000MS, Myrj 59FL, S 40, Lanoxide 52, Lanoxide 59, MYS 25, Kessco PEG 1540MS, E 430, Myrj 53P, Emalex 830, Nikkol MYS 40V, Myrj 59P, Nikkol MYS 45MV, Nikkol MYS 10V, Pegosperse 600MS, Blaunon S 1000A, Emalex 810, Polyoxyl stearate, Blaunon S 300A, Hydrine, Nikkol MYS 25V, Estol 3723, Tego Acid S 100P, Simulsol 59, Emalex 400B, Atlas G 2147, Atlas G 2154, Atlas G 2159, Emulgen 3199, Pionin D 2405A, Crodet S 40LD, Nikkol MYS 40MV, Nikkol MYS 55V, Emalex 840, Emalex 820, Emanon 3199V, Koremul SA 9, MYS 40MV, Crodet S 40, Myrj S 40, Myrj S 50, Myrj S 100, Myrj S 20, Myrj 56, Emanon 3199B, Myrj S 8SO, Standapol 2662, PEG monostearate, Myrj 30, Myrj 35, Pegosperse 1500MS, Emalex 805, G 2151, Nikkol MYS 45V, Myrj 40, SA 9, Emanon 3119V, PEG 75 stearate, PEG 400 monoester with stearic acid, Lasemul 4000, S 20, MYS 25V, SG 50 (polyoxyalkylene), Hallstar 4400, EE 400, MYRJ-S 40FL-TH, MYS 10V, Emalex 8100, Nikkol MYS 2V, Nikkol MYS 55MV, Ritox 52, BS 1000G, Sympatens BS 1000G, Cithrol 6MS, Emanon 3199VB, MYS 4V, SG 30, SG 15, SG 25, Myrj S 8, E 1750MS/FLK, SG 12,



PEG 400 Monostearate is a polyether compound that is used in a wide variety of fields including pharmaceutical manufacturing as an excipient.
PEG 400 Monostearate is a white solid.
PEG 400 Monostearate is an octadecanoate ester composed of repeating 8-40 ethyleneoxy units.


PEG 400 Monostearate is an ingredient used in cosmetics and beauty products primarily as a surfactant and emulsifier.
PEG 400 Monostearate has a role as a nonionic surfactant, an emulsifier and a food emulsifier.
PEG 400 Monostearate is a hydroxypolyether and an octadecanoate ester.


PEG 400 Monostearate is a surfactant that functions as an emulsifier, dispersing agent, and wetting agent.
PEG 400 Monostearate is soluble in a variety of organic solvents and is dispersed in water, with emulsifying, solubilizing, wetting and softening properties.


PEGs of all sizes may penetrate through injured skin with compromised barrier function.
Unlike typical PEGs, (whose identifying number corresponds to their molecular weight) the numerical value of each PEG Stearate corresponds to the average number of ethylene oxide monomers in the polyethylene chain (from 2 - 150).
Skin penetration enhancing effects have been shown with PEG-2 and PEG-9 stearate.


This penetration-enhancing effect is important for three reasons:
*If your skin care product contains a bunch of other undesirable ingredients, PEGs will make it easier for them to get down deep into your skin.
*By altering the surface tension of the skin, PEGs may upset the natural moisture balance.
*PEGs are not always pure, but often come contaminated with a host of toxic impurities.



USES and APPLICATIONS of PEG 400 MONOSTEARATE:
Due to its low toxicity PEG 400 Monostearate can be used as a lubricating coating for various surfaces in aqueous and non-aqueous environments, a reagent in biochemistry to create very high osmotic pressures, a polar stationary phase for gas chromatography and as a binder.
PEG 400 Monostearate is a polyether compound that is used in a wide variety of fields including pharmaceutical manufacturing as an excipient.


PEG 400 Monostearate is used in personal care products, pharmaceuticals, and medical devices.
PEG 400 Monostearate has been shown to be effective in the treatment of allergic symptoms and eye disorders caused by glycols.
The analytical method for measuring PEG 400 Monostearate involves metal hydroxides such as copper(II) hydroxide. Polyoxyethylene stearate has also been shown to have anti-infective properties in wastewater treatment systems.


PEG 400 Monostearate has been found to be toxic when given orally or injected into laboratory animals; however, it does not cause irritation at low concentrations when applied to the skin.
PEG 400 Monostearate is used as a surfactant, emulsifier (cosmetics, pharmaceuticals, textile finishes, defoamers, and baked goods), dye assistant, lubricant, and antistatic agent.


PEG 400 Monostearate is also used in dentifrice compositions and to make creams, lotions, ointments, and pharmaceutical preparations.
PEG 400 Monostearate is used as emulsifier, softener and lubricant in textile industry.
PEG 400 Monostearate is used as detergent, lubricant and brightener in cosmetics and metal processing industry.


PEG 400 Monostearate is used as thickener and stabilizer for paper starch coating in paper industry.
PEG 400 Monostearate is used as a water Dispersing paper sizing agent and softening agent.


PEG 400 Monostearate is used as an emulsifier for liquid medicine and emulsion medicine in the pharmaceutical industry.
PEG 400 Monostearate is also used as an emulsifier for oils and fats; grinding aid for paint and printing ink.



FUNCTION OF PEG 400 MONOSTEARATE:
Is an ester formed by the reaction of high purity stearic acid and PEG 400 Monostearate.
PEG 400 Monostearate is an emulsifier for oil-in-water emulsions and an auxiliary emulsifier for water-in-oil emulsions.
In shampoos, PEG 400 Monostearate is a hair conditioner and foam builder and known to improve cleansing action by preventing the redeposition of grease and dirt on the hair by a protective colloid effect.
PEG 400 Monostearate is also used in formulations of ointments, creams, lotions and suspensions.



STORAGE OF PEG 400 MONOSTEARATE:
Keep PEG 400 Monostearate container tightly closed.
Keep PEG 400 Monostearate container in a cool, well-ventilated area.



PHYSICAL and CHEMICAL PROPERTIES of PEG 400 MONOSTEARATE:
Appearance Form: solid
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point:
Melting point: 41 °C
Initial boiling point and boiling range: No data available
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Density: No data available
Relative density: No data available

Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
CAS: 9004-99-3
CAS Max %: 1
SMILES: CCCCCCCCCCCCCCCCCC(=O)OCCO
Molecular Weight (g/mol): 328.54
Hydroxyl Value: 80-100
Acid Value: 2
Molecular Formula: C20H40O3

InChI Key: RFVNOJDQRGSOEL-UHFFFAOYSA-N
IUPAC Name: 2-hydroxyethyl octadecanoate
Grade: Reagent
Moisture: 0.03
CAS: 9004-99-3
Molecular Weight (g/mol): 328.54
IUPAC Name: 2-hydroxyethyl octadecanoate
Molecular Formula: C20H40O3
InChI Key: RFVNOJDQRGSOEL-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCCCCCCC(=O)OCCO
Spectra: Base Spectrum ID: EMoQTpYwnb
Name: POLYETHYLENE GLYCOL(400) MONOSTEARATE
Compound Type: Pure
Molecular Weight: ~700
Molecular Weight: 328.5 g/mol
Molecular Formula: C20H40O3
XLogP3: 7.8

Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 19
Exact Mass: 328.29774513 g/mol
Monoisotopic Mass: 328.29774513 g/mol
Topological Polar Surface Area: 46.5 Ų
Heavy Atom Count: 23
Formal Charge: 0
Complexity: 241
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently Bonded Unit Count: 1


CAS Number: 9004-99-3
Molecular Weight: 328.530
Density: 0.9±0.1 g/cm3
Boiling Point: 438.4±18.0 °C at 760 mmHg
Molecular Formula: C20H40O3
Melting Point: 47ºC
Flash Point: 164.6±14.0 °C
Density: 0.9±0.1 g/cm3
Boiling Point: 438.4±18.0 °C at 760 mmHg
Melting Point: 47ºC
Molecular Formula: C20H40O3
Molecular Weight: 328.530
Flash Point: 164.6±14.0 °C
Exact Mass: 328.297760
PSA: 46.53000
LogP: 7.85
Vapour Pressure: 0.0±2.4 mmHg at 25°C
Index of Refraction: 1.457



FIRST AID MEASURES of PEG 400 MONOSTEARATE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of PEG 400 MONOSTEARATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of PEG 400 MONOSTEARATE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of PEG 400 MONOSTEARATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of PEG 400 MONOSTEARATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
*Storage stability:
Recommended storage temperature: 2 - 8 °C



STABILITY and REACTIVITY of PEG 400 MONOSTEARATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available

PEG 4000 Polyethylene glycol (PEG 4000; /ˌpɒliˈɛθəlˌiːn ˈɡlaɪˌkɒl, -ˌkɔːl/) is a polyether compound with many applications, from industrial manufacturing to medicine. PEG 4000 is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight. The structure of PEG 4000 is commonly expressed as H−(O−CH2−CH2)n−OH. Uses of Polyethylene glycol (PEG 4000 Medical uses of Polyethylene glycol (PEG 4000) Main article: Macrogol PEG 4000 is the basis of a number of laxatives.[4] Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy. PEG 4000 is also used as an excipient in many pharmaceutical products. When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood.[5] The possibility that PEG 4000 could be used to fuse axons is being explored by researchers studying peripheral nerve and spinal cord injury.[4] Chemical uses of Polyethylene glycol (PEG 4000) The remains of the 16th century carrack Mary Rose undergoing conservation treatment with PEG 4000 in the 1980s Terra cotta warrior, showing traces of original color Because PEG 4000 is a hydrophilic molecule, it has been used to passivate microscope glass slides for avoiding non-specific sticking of proteins in single-molecule fluorescence studies.[6] Polyethylene glycol has a low toxicity and is used in a variety of products.[7] The polymer is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments.[8] Since PEG 4000 is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures (on the order of tens of atmospheres). It also is unlikely to have specific interactions with biological chemicals. These properties make PEG 4000 one of the most useful molecules for applying osmotic pressure in biochemistry and biomembranes experiments, in particular when using the osmotic stress technique. Polyethylene glycol is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers. PEG 4000 has also been used to preserve objects that have been salvaged from underwater, as was the case with the warship Vasa in Stockholm,[9] and similar cases. It replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.[4] In addition, PEG 4000 is used when working with green wood as a stabilizer, and to prevent shrinkage.[10] PEG 4000 has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China.[11] These painted artifacts were created during the Qin Shi Huang (first emperor of China) era. Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xi'an air. The paint would subsequently flake off in about four minutes. The German Bavarian State Conservation Office developed a PEG 4000 preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.[12] PEG 4000 is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning. PEG 4000 derivatives, such as narrow range ethoxylates, are used as surfactants. PEG 4000 has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.[13] PEG 4000 has also been used as a propellent on the UGM-133M Trident II Missile, in service with the United States Air Force.[14] Biological uses PEG 4000 is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.[6] PEG 4000 is commonly used as a precipitant for plasmid DNA isolation and protein crystallization. X-ray diffraction of protein crystals can reveal the atomic structure of the proteins. PEG 4000 is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas. Polymer segments derived from PEG 4000 polyols impart flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam cushions. In microbiology, PEG 4000 precipitation is used to concentrate viruses. PEG 4000 is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro. Gene therapy vectors (such as viruses) can be PEG 4000-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect.[15] The size of the PEG 4000 polymer has been shown to be important, with larger polymers achieving the best immune protection. PEG 4000 is a component of stable nucleic acid lipid particles (SNALPs) used to package siRNA for use in vivo. In blood banking, PEG 4000 is used as a potentiator to enhance detection of antigens and antibodies. When working with phenol in a laboratory situation, PEG 4000 300 can be used on phenol skin burns to deactivate any residual phenol (some references are required). In biophysics, polyethylene glycols are the molecules of choice for the functioning ion channels diameter studies, because in aqueous solutions they have a spherical shape and can block ion channel conductance. Commercial uses PEG 4000 is the basis of many skin creams (as cetomacrogol) and personal lubricants (frequently combined with glycerin). PEG 4000 is used in a number of toothpastes[4] as a dispersant. In this application, it binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste. PEG 4000 is also under investigation for use in body armor, and in tattoos to monitor diabetes. In low-molecular-weight formulations (e.g. PEG 4000 400), it is used in Hewlett-Packard designjet printers as an ink solvent and lubricant for the print heads. PEG 4000 is also used as an anti-foaming agent in food and drinks[23] – its INS number is 1521 or E1521 in the EU. Industrial uses A nitrate ester-plasticized polyethylene glycol (NEPE-75) is used in Trident II submarine-launched ballistic missile solid rocket fuel.[26] Dimethyl ethers of PEG 4000 are the key ingredient of Selexol, a solvent used by coal-burning, integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the gas waste stream. PEG 4000 has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.[27] PEG 4000 is also used as a polymer host for solid polymer electrolytes. Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving PEG 4000, with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future. PEG 4000 is injected into industrial processes to reduce foaming in separation equipment. PEG 4000 is used as a binder in the preparation of technical ceramics.[28] Recreational uses PEG 4000 is used to extend the size and durability of very large soap bubbles. PEG 4000 is the main ingredient in many personal lubricants. Health effects PEG 4000 is considered biologically inert and safe by the FDA. However, a growing body of evidence shows the existence of anti PEG 4000 antibodies in approximately 72% of the population based on plasma samples from 1990–1999.[medical citation needed] The FDA has been asked to investigate the possible effects of PEG 4000 in laxatives for children.[29] Due to its ubiquity in a multitude of products and the large percentage of the population with antibodies to PEG 4000, hypersensitive reactions to PEG 4000 are an increasing concern.[medical citation needed] Allergy to PEG 4000 is usually discovered after a person has been diagnosed with an allergy to an increasing number of seemingly unrelated products, including processed foods, cosmetics, drugs, and other substances that contain PEG 4000 or were manufactured with PEG 4000.[30] When PEG 4000 is chemically attached to therapeutic molecules (such as protein drugs or nanoparticles), it can sometimes be antigenic, stimulating an anti-PEG 4000 antibody response in some patients. This effect has only been shown for a few of the many available PEG 4000 therapeutics, but it has significant effects on clinical outcomes of affected patients.[31] Other than these few instances where patients have anti-PEG 4000 immune responses, it is generally considered to be a safe component of drug formulations. Available forms and nomenclature PEG 4000, PEO, and POE refer to an oligomer or polymer of ethylene oxide. The three names are chemically synonymous, but historically PEG 4000 is preferred in the biomedical field, whereas PEO is more prevalent in the field of polymer chemistry. Because different applications require different polymer chain lengths, PEG 4000 has tended to refer to oligomers and polymers with a molecular mass below 20,000 g/mol, PEO to polymers with a molecular mass above 20,000 g/mol, and POE to a polymer of any molecular mass.[32] PEG 4000s are prepared by polymerization of ethylene oxide and are commercially available over a wide range of molecular weights from 300 g/mol to 10,000,000 g/mol.[33] PEG 4000 and PEO are liquids or low-melting solids, depending on their molecular weights. While PEG 4000 and PEO with different molecular weights find use in different applications, and have different physical properties (e.g. viscosity) due to chain length effects, their chemical properties are nearly identical. Different forms of PEG 4000 are also available, depending on the initiator used for the polymerization process – the most common initiator is a monofunctional methyl ether PEG 4000, or methoxypoly(ethylene glycol), abbreviated mPEG 4000. Lower-molecular-weight PEG 4000s are also available as purer oligomers, referred to as monodisperse, uniform, or discrete. Very high purity PEG 4000 has recently been shown to be crystalline, allowing determination of a crystal structure by x-ray diffraction.[33] Since purification and separation of pure oligomers is difficult, the price for this type of quality is often 10–1000 fold that of polydisperse PEG 4000. PEG 4000s are also available with different geometries. Branched PEG 4000s have three to ten PEG 4000 chains emanating from a central core group. Star PEG 4000s have 10 to 100 PEG 4000 chains emanating from a central core group. Comb PEG 4000s have multiple PEG 4000 chains normally grafted onto a polymer backbone. The numbers that are often included in the names of PEG 4000s indicate their average molecular weights (e.g. a PEG 4000 with n = 9 would have an average molecular weight of approximately 400 daltons, and would be labeled PEG 4000 400.) Most PEG 4000s include molecules with a distribution of molecular weights (i.e. they are polydisperse). The size distribution can be characterized statistically by its weight average molecular weight (Mw) and its number average molecular weight (Mn), the ratio of which is called the polydispersity index (Mw/Mn). Mw and Mn can be measured by mass spectrometry. PEG 4000ylation is the act of covalently coupling a PEG 4000 structure to another larger molecule, for example, a therapeutic protein, which is then referred to as a PEG 4000 protein. PEG 4000 interferon alfa-2a or −2b are commonly used injectable treatments for hepatitis C infection. PEG 4000 is soluble in water, methanol, ethanol, acetonitrile, benzene, and dichloromethane, and is insoluble in diethyl ether and hexane. It is coupled to hydrophobic molecules to produce non-ionic surfactants.[34] PEG 4000s potentially contain toxic impurities, such as ethylene oxide and 1,4-dioxane.[35] Ethylene Glycol and its ethers are nephrotoxic if applied to damaged skin.[36] Polyethylene oxide (PEO, Mw 4 kDa) nanometric crystallites (4 nm) Polyethylene glycol (PEG 4000) and related polymers (PEG 4000 phospholipid constructs) are often sonicated when used in biomedical applications. However, as reported by Murali et al., PEG 4000 is very sensitive to sonolytic degradation and PEG 4000 degradation products can be toxic to mammalian cells. It is, thus, imperative to assess potential PEG 4000 degradation to ensure that the final material does not contain undocumented contaminants that can introduce artifacts into experimental results.[37] PEG 4000s and methoxypolyethylene glycols are manufactured by Dow Chemical under the tradename Carbowax for industrial use, and Carbowax Sentry for food and pharmaceutical use. They vary in consistency from liquid to solid, depending on the molecular weight, as indicated by a number following the name. They are used commercially in numerous applications, including as surfactants, in foods, in cosmetics, in pharmaceutics, in biomedicine, as dispersing agents, as solvents, in ointments, in suppository bases, as tablet excipients, and as laxatives. Some specific groups are lauromacrogols, nonoxynols, octoxynols, and poloxamers. Macrogol, used as a laxative, is a form of polyethylene glycol. The name may be followed by a number which represents the average molecular weight. Production of Polyethylene glycol (PEG 4000) Polyethylene glycol 400, pharmaceutical quality Polyethylene glycol 4000, pharmaceutical quality The production of polyethylene glycol was first reported in 1859. Both A. V. Lourenço and Charles Adolphe Wurtz independently isolated products that were polyethylene glycols.[38] Polyethylene glycol is produced by the interaction of ethylene oxide with water, ethylene glycol, or ethylene glycol oligomers.[39] The reaction is catalyzed by acidic or basic catalysts. Ethylene glycol and its oligomers are preferable as a starting material instead of water, because they allow the creation of polymers with a low polydispersity (narrow molecular weight distribution). Polymer chain length depends on the ratio of reactants. HOCH2CH2OH + n(CH2CH2O) → HO(CH2CH2O)n+1H Depending on the catalyst type, the mechanism of polymerization can be cationic or anionic. The anionic mechanism is preferable because it allows one to obtain PEG 4000 with a low polydispersity. Polymerization of ethylene oxide is an exothermic process. Overheating or contaminating ethylene oxide with catalysts such as alkalis or metal oxides can lead to runaway polymerization, which can end in an explosion after a few hours. Polyethylene oxide, or high-molecular weight polyethylene glycol, is synthesized by suspension polymerization. It is necessary to hold the growing polymer chain in solution in the course of the polycondensation process. The reaction is catalyzed by magnesium-, aluminium-, or calcium-organoelement compounds. To prevent coagulation of polymer chains from solution, chelating additives such as dimethylglyoxime are used. Alkaline catalysts such as sodium hydroxide (NaOH), potassium hydroxide (KOH), or sodium carbonate (Na2CO3) are used to prepare low-molecular-weight polyethylene glycol. Polyethylene glycol (PEG 4000) is a versatile polyether being utilized in various applications, in particular in medicine. Polyethylene oxide (PEO) is another name for PEG 4000. Typically, ethylene oxide macromolecules (Fig. 18.9) with molecular weights less than 20,000 g/mol are called PEG 4000, while those having values above 20,000 g/mol are named PEO. It is reported that PEG 4000 is soluble in water, ethanol, acetonitrile, benzene, and dichloromethane, while it is insoluble in diethyl ether and hexane. PEG 4000 is available in different structures such as branched, star, and comb-like macromolecules. PEG 4000ylation is an attractive process in which PEG 4000 is bonded to another molecule, which is promising in therapeutic methods. PEG 4000 can hinder the protein adsorption which is essential in drug delivery to minimize the protein corona formation [29]. Polyethylene glycol (PEG 4000) is a hydrophilic polymer of ethylene oxide. The non-immunogenic, biocompatible and flexible nature of PEG 4000 makes it a suitable synthetic dressing material for wound healing. The low toxic PEG 4000 macromers are well bonded with growth factor like EGF and can be delivered at the wound site [98]. The mechanical stability of PEG 4000 can be enhanced by blending PEG 4000 with chitosan and PLGA. Blending also increases thermal stability and crystallinity of the particular polymer [99]. Such PEG 4000-based dressings have been widely used to treat a diabetic wound by promoting and inducing growth of skin cells and collagen deposition. It also reduces scar formation [100]. The injectable hybrid hydrogel dressing system is developed from PEG 4000-based hyperbranched multiacrylated co-polymer and HA in combination with adipose-derived stem cells to support the viability of cells in vitro and in vivo. It prevents wound contraction and enhances angiogenesis by acting as temporary hydrogel for wound healing purpose [101]. Hydrophilic Materials Based on Polyethylene Glycol Polyethylene glycol (PEG 4000) is the most relevant antifouling polymer in biomedical devices. PEG 4000 antifouling properties are thought to be related to surface hydration and steric hindrance effects (Chen et al., 2010). PEG 4000 chains linked to a material surface assume a brush-like configuration at the water/surface interface, limiting the approach to the surface by bacteria. Compression of the highly hydrated layer of PEG 4000 chains is unfavorable because it would involve a reduction in PEG 4000 chain mobility and removal of water molecules. Surface packing density and polymer chain length can be used to control PEG 4000 antifouling properties (Roosjen et al., 2004). PEG 4000-functionalized PUs were developed by PEG 4000 introduction either in the polymer backbone (Corneillie et al., 1998) or polymer side chain (Francolini et al., 2019). Auto-oxidization in the presence of oxygen, metal ions, and enzymes able to oxidize PEG 4000 hydroxyl groups, however, may limit long-term effectiveness. Polyethylene glycol (PEG 4000) is another important type of PCM for textile applications. The repeating unit in PEG 4000 is oxyethylene (–O–CH2–CH2–) containing hydroxyl group on either side of the chain. The melting point of PEG 4000 depends on its molecular weight and is proportional as the molecular weight increases. The phase-change temperature of PEG 4000 can be determined using DSC (Pielichowski and Flejtuch, 2002). PEG 4000 with degree of polymerization 1000 has phase-change temperature of 35°C, while PEG 4000 with degree of polymerization 20,000 has melting temperature of 63°C (Craig and Newton, 1991; Hopp et al., 2000). Jiang et al. (2016) synthesized a dual-functional magnetic microcapsules containing a PCM core and an organo-silica shell for the electromagnetic shielding and thermal regulating applications. Fig. 20.6 shows the resulting DSC curves where the areas under the peaks indicate the amount of latent heat contained using different organosilanes/PEG 4000 weight ratios. PEG 4000 is the basis of a number of laxatives.[3] Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy. PEG 4000 is also used as an excipient in many pharmaceutical products. When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood.[4] The possibility that PEG 4000 could be used to fuse nerve cells is being explored by researchers studying spinal cord injury.[3] Chemical uses The remains of the 16th century carrack Mary Rose undergoing conservation treatment with PEG 4000 in the 1980s Terra cotta warrior, showing traces of original color Because PEG 4000 is a hydrophilic molecule, it has been used to passivate microscope glass slides for avoiding non-specific sticking of proteins in single-molecule fluorescence studies.[5] Polyethylene glycol has a low toxicity and is used in a variety of products.[6] The polymer is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments.[7] Since PEG is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures (on the order of tens of atmospheres). It also is unlikely to have specific interactions with biological chemicals. These properties make PEG 4000 one of the most useful molecules for applying osmotic pressure in biochemistry and biomembranes experiments, in particular when using the osmotic stress technique. Polyethylene glycol is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers. PEG 4000 has also been used to preserve objects that have been salvaged from underwater, as was the case with the warship Vasa in Stockholm,[8] and similar cases. It replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.[3] In addition, PEG 4000 is used when working with green wood as a stabilizer, and to prevent shrinkage.[9] PEG has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China.[10] These painted artifacts were created during the Qin Shi Huang Di dynasty (first emperor of China). Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xian air. The paint would subsequently flake off in about four minutes. The German Bavarian State Conservation Office developed a PEG 4000 preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.[11] PEG 4000 is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning. PEG 4000 derivatives, such as narrow range ethoxylates, are used as surfactants. PEG 4000 is a polyol and can be reacted with an isocyanate to make polyurethane. PEG 4000 has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.[12] Biological uses PEG 4000 is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions. PEG 4000 is commonly used as a precipitant for plasmid DNA isolation and protein crystallization. X-ray diffraction of protein crystals can reveal the atomic structure of the proteins. PEG is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas. César Milstein and Georges J. F. Köhler originated this technique, which they used for antibody production, winning a Nobel Prize in Physiology or Medicine in 1984.[3] Polymer segments derived from PEG polyols impart flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam cushions. In microbiology, PEG 4000 precipitation is used to concentrate viruses. PEG is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro. Gene therapy vectors (such as viruses) can be PEG-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect.[13] The size of the PEG polymer has been shown to be important, with larger polymers achieving the best immune protection. PEG is a component of stable nucleic acid lipid particles (SNALPs) used to package siRNA for use in vivo. In blood banking, PEG is used as a potentiator to enhance detection of antigens and antibodies.[3][16] When working with phenol in a laboratory situation, PEG 300 can be used on phenol skin burns to deactivate any residual phenol. In biophysics, polyethylene glycols are the molecules of choice for the functioning ion channels diameter studies, because in aqueous solutions they have a spherical shape and can block ion channel conductance. What is Polyethyleneglycol? Polyethyleneglycol, or PEG 4000 for short, is a polyether consisting of a (-O-CH2-CH2-) backbone that is commonly used in many fields of academic research, industrial processing and commercial applications. PEG 4000s can also commonly be referred to as polyoxyethylene (POE) and polyethyleneoxide (PEO), but regardless of the name that is used, the simple structure of PEG 4000s (which consists of solely carbon, hydrogen and oxygen, see image below) affords safe compounds that are used throughout everyday life. Additionally, it is this simple structure that separates PEG 4000s from similar compounds like propylene glycol and polypropyleneglycol. The two aforementioned compounds (polyethyleneglycol vs. propylene glycol) are derivatives of propylene oxide, which, when polymerized, bestows a completely different set of physical characteristics to the compound as compared to PEG 4000. The method in which PEG 4000s are created allows for a wide variability in their physical attributes, allowing them to be utilized by many commercial markets. By controlling a PEG 4000’s size (i.e. molecular weight) and its size distribution, a wide variety of physical properties can be achieved, which sets Oxiteno’s line of PEG 4000 products, the 6000 powder series, apart from other name brands of polyethyleneglycols. Due to the vast number of product types offered 6000 powder products (click here for a full listing), many physical forms (liquids, pastes, solids, flakes, powder, etc.) and viscosities of PEG 4000s are available. It is the numerous attributes of PEG 4000s that allow for their inclusion in a vast array of applications, ranging from the pharmaceutical industry to cosmetic markets. While the structure of PEG 4000 is simple, it is this compound’s solubility in water is what makes it such a versatile additive to enhance many industrial applications. Because line of PEG 4000 products are non-toxic and hydrophilic (water-loving), these polymers are used in the home (i.e. to treat surfaces in cleaning agents made by cleaning chemicals manufacturers) as well as in the food production industry (to reduce the amount of foam during the processing of food products). PEG 4000s are generally considered to be biologically inert, making them safe to use throughout the medical and food-processing industries. What is Polyethyleneglycol Used For? Due to the variety of physical properties that can be achieved through PEG 4000 series, formulators in nearly all industries can benefit from this line of PEG 4000 products. A PEG 4000’s unique ability to enhance a dye’s solubility in aqueous formulations causes it to be used throughout the textile industry as dye carriers. PEG 4000s are also exceptional at retaining moisture in complex formulations, as well as to an applied surface, making them excellent humectants and anti-caking agents for cosmetic chemical suppliers and coatings chemical suppliers. This unique relationship with water is further exploited by many other markets as PEG 4000s can help to stabilize emulsions and act as water-miscible co-solvents for aqueous formulations. The food industry uses these compounds as additives to reduce the amount of foam during food processing. Additionally, PEG 4000s find themselves very useful in the pharmaceutical industry due to their ability to act as rheological modifiers, thus being used as excipients. New research techniques are increasingly incorporating PEG 4000 compounds via the use of ‘PEG 4000ylation’ onto protein and peptide therapeutics, thus improving their pharmacokinetics and leading to safer and more effective drugs1-2. Many of PEG 4000 series meet the requirements set forth by the National Formulary (NF) guidelines for safe preparation, manufacture and use of a variety of PEG 4000 compounds that can be used as excipients, botanicals and other similar products. Is Polyethyleneglycol Safe? PEG 4000s are generally considered to be a biologically inert substance, meaning that this class of oligomers and polymers are recognized to be safe for use in food, cosmetic and pharmaceutical applications. So, is polyethyleneglycol toxic? Due to the PEG 4000’s structure and its water solubility, these compounds are generally considered to be non-toxic, as studies of demonstrated their safety for use within the field of drug delivery1-2, for application to the skin in cosmetics3 and as additives in the food and vitamin processing industry4. Where applicable, line of PEG 4000s, 6000 powder, adhere to the guidelines for the manufacturing set forth by the National Formulary (NF). Having initially been established by the U.S. Federal Food, Drug, and Cosmetics Act of 1938, these guidelines are currently recognized by the U.S. Food and Drug Administration (FDA). These manufacturing and production guidelines are annually reviewed, requiring to not only adhere to these strict standards, but maintain constant surveillance over the preparation of these non-toxic additives. Additionally, many of PEG 4000 products that are used in agricultural applications are safe for the environment and are on the Environmental Protection Agencies’ (EPA) inert ingredient list, meeting the requirements set forth in 40 CFR 180.910 and 40 CFR 180.930. This makes PEG 4000s attractive for agrochemical companies. Polyethylene Glycol · Adhesives · Agriculture · Ceramics · Chemical Intermediates · Cosmetics · Toiletries · Electroplating / Electropolishing · Food Processing · Household Products · Lubricants · Metal / Metal Fabrication · Paints & Coatings · Paper Industry · Pharmaceuticals · Printing · Rubber & Elastomers · Textiles · Wood Processing AVAILABLE FORMS AND NOMENCLATURE PEG 4000, PEO, and POE refer to an oligomer or polymer of ethylene oxide. The three names are chemically synonymous, but historically PEG 4000 is preferred in the biomedical field, whereas PEO is more prevalent in the field of polymer chemistry. Because different applications require different polymer chain lengths, PEG 4000 has tended to refer to oligomers and polymers with a molecular mass below 20,000 g/mol, PEO to polymers with a molecular mass above 20,000 g/mol, and POE to a polymer of any molecular mass PEG 4000s are prepared by polymerization of ethylene oxide and are commercially available over a wide range of molecular weights from 300 g/mol to 10,000,000 g/mol.[ PEG 4000 and PEO are liquids or low-melting solids, depending on their molecular weights. While PEG 4000 and PEO with different molecular weights find use in different applications, and have different physical properties (e.g. viscosity) due to chain length effects, their chemical properties are nearly identical. Different forms of PEG 4000 are also available, depending on the initiator used for the polymerization process - the most common initiator is a monofunctional methyl ether PEG 4000, or methoxypoly(ethylene glycol), abbreviated mPEG 4000. Lower-molecular-weight PEG 4000s are also available as purer oligomers, referred to as monodisperse, uniform, or discrete. Very high purity PEG 4000 has recently been shown to be crystalline, allowing determination of a crystal structure by x-ray diffraction Since purification and separation of pure oligomers is difficult, the price for this type of quality is often 10-1000 fold that of polydisperse PEG 4000. PEG 4000s are also available with different geometries. The numbers that are often included in the names of PEG 4000s indicate their average molecular weights (e.g. a PEG 4000 with n = 9 would have an average molecular weight of approximately 400 daltons, and would be labeled PEG 4000 400.) Most PEG 4000s include molecules with a distribution of molecular weights (i.e. they are polydisperse). The size distribution can be characterized statistically by its weight average molecular weight (Mw) and its number average molecular weight (Mn), the ratio of which is called the polydispersity index(Mw/Mn). Mw and Mn can be measured by mass spectrometry. PEG 4000 is the act of covalently coupling a PEG 4000 structure to another larger molecule, for example, a therapeutic protein, which is then referred to as a PEG 4000 protein. PEG 4000 interferon alfa-2a or -2b are commonly used injectable treatments for hepatitis C infection. PEG 4000 is soluble in water, methanol, ethanol, acetonitrile, benzene, and dichloromethane, and is insoluble in diethyl ether and hexane. It is coupled to hydrophobic molecules

PEG 6 IUPAC Name decanoic acid;hexadecanoic acid;octadecanoic acid;octanoic acid;propane-1,2,3-triol PEG 6 InChI InChI=1S/C18H36O2.C16H32O2.C10H20O2.C8H16O2.C3H8O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18;1-2-3-4-5-6-7-8-9-10(11)12;1-2-3-4-5-6-7-8(9)10;4-1-3(6)2-5/h2-17H2,1H3,(H,19,20);2-15H2,1H3,(H,17,18);2-9H2,1H3,(H,11,12);2-7H2,1H3,(H,9,10);3-6H,1-2H2 PEG 6 InChI Key NGPTYCZGBCGWBE-UHFFFAOYSA-N PEG 6 Canonical SMILES CCCCCCCCCCCCCCCCCC(=O)O.CCCCCCCCCCCCCCCC(=O)O.CCCCCCCCCC(=O)O.CCCCCCCC(=O)O.C(C(CO)O)O PEG 6 Molecular Formula C55H112O11 PEG 6 CAS 77944-79-7 PEG 6 Molecular Weight 949.5 g/mol PEG 6 Hydrogen Bond Donor Count 7 PEG 6 Hydrogen Bond Acceptor Count 11 PEG 6 Rotatable Bond Count 46 PEG 6 Exact Mass 948.820464 g/mol PEG 6 Monoisotopic Mass 948.820464 g/mol PEG 6 Topological Polar Surface Area 210 Ų PEG 6 Heavy Atom Count 66 PEG 6 Formal Charge 0 PEG 6 Complexity 604 PEG 6 Isotope Atom Count 0 PEG 6 Defined Atom Stereocenter Count 0 PEG 6 Undefined Atom Stereocenter Count 0 PEG 6 Defined Bond Stereocenter Count 0 PEG 6 Undefined Bond Stereocenter Count 0 PEG 6 Covalently-Bonded Unit Count 5 PEG 6 Compound Is Canonicalized Yes PEG 6 benefits PEG 6s are compounds made from naturally occurring fatty acids. It is a clear liquid and slightly sweet in taste. Along with their high fat content, texture and antioxidant qualities in triglycerides, they use them exclusively for soaps and skin care products. PEG 6 Emolyan Softeners are ingredients that soften your skin. Softeners work by trapping moisture in your skin and creating a protective layer to keep moisture out. PEG 6 is an effective skin softening agent. PEG 6 Dispersing agent Dispersants are parts of any chemical or organic compound that hold the ingredients together and stabilize them.Mixing other active ingredients, pigments or fragrances in a good dispersing agent prevents the ingredients from mixing together or sinking into the bottom of the mixture. The waxy and thick consistency of PEG 6s makes them an excellent dispersing agent. PEG 6 Solvent Solvents are ingredients that can dissolve or break down some ingredients or compounds. Ingredients are solvents based on how their molecules are constructed and shaped, and how they interact with other substances.PEG 6 can dissolve compounds designed to clump together. While some solvents have toxic components, PEG 6 does not carry these risks. PEG 6 Antioxidant Antioxidants work to neutralize the toxins you are exposed to every day in your environment. Antioxidants stop the chain reaction called oxidation that can age your skin and damage your body.PEG 6 is full of antioxidants that help protect your skin and make you feel younger. PEG 6 uses PEG 6 can be found in topical skin care products you use on and around your face. Used for: Extends the shelf life of these products,add a light and oil-free glow to your skin,increasing the antioxidants in the product. These products include: Moisturizing face creams,anti aging serums,sunscreens,eye creams. PEG 6 in cosmetics PEG 6 is a popular ingredient in makeup and other cosmetics. The ingredient distributes pigments evenly in a cosmetic formula without leaving your skin feeling sticky. This ingredient is often listed in these cosmetics: Lipstick,lip balm,Lip pencil,cream and liquid foundations,eyeliner. Is PEG 6 safe? PEG 6 carries very low toxicity, if available for topical use. The FDA states that it is generally considered safe in low amounts as a food additive. This means that consuming trace amounts that may be in your lipstick or lip balm is non-toxic.If you do not have a severe allergy to coconut oil, the risk of allergic reactions triggered by using PEG 6 is very low.There are some environmental concerns for PEG 6 use. We don't know enough about how it disperses in nature and whether it could ultimately pose a threat to wildlife. More research is needed to determine the safest ways to dispose of products containing PEG 6s. PEG 6 Take away Current research states that PEG 6 is safe for most people. Consuming small amounts as a food additive, sweetener or cosmetic product does not pose a risk to your health.Capric acid / PEG 6 is one of the cleanest ingredients you can find as a natural alternative to chemical ingredients.Everyone's skin reacts differently to different chemicals. Always be careful when using a new cosmetic product or face cream. PEG 6 is an ingredient used in soap and cosmetics. It is usually made by combining coconut oil with glycerin. This component is sometimes called capric triglyceride. Sometimes mistakenly fractionated is also called coconut oil.PEG 6 has been widely used for more than 50 years. It smoothes the skin and works as an antioxidant. It also binds other ingredients together and can work as a kind of preservative to make the active ingredients in cosmetics last longer.PEG 6 is valued as a more natural alternative to other synthetic chemicals found in topical skin products. Companies that claim their products to be "all natural" or "organic" often contain PEG 6.Although technically made from natural ingredients, the PEG 6 used in products is generally not found in nature. A chemical process separates the oily liquid so a "pure" version can be added to the products.It is low viscosity, softener and lubricant that does not feel greasy. It is widely used especially in "oil-free" products. It is a great advantage that it is not oxidized. It is an ideal solvent for active ingredients to be used in skin and hair care, as well as make-up products.Derived from coconut oil and glycerin, it’s considered an excellent emollient and skin-replenishing ingredient. It’s included in cosmetics due to its mix of fatty acids that skin can use to replenish its surface and resist moisture loss. PEG 6 can also function as a thickener, but its chief job is to moisturize and replenish skin. This ingredient’s value for skin is made greater by the fact that it’s considered gentle.PEG 6 is an oily liquid made from palm kernel or coconut oil. It is a mixed ester composed of caprylic and capric fatty acids attached to a glycerin backbone. PEG 6 are sometimes erroneously referred to as fractionated coconut oil, which is similar in composition but typically refers to coconut oil that has had its longer chain triglycerides removed. Chemically speaking, fats and oils are made up mostly of triglycerides whose fatty acids are chains ranging from 6–12 carbon atoms, in this case the ester is comprised of capric (10 carbon atoms) and caprylic (8 carbon atoms).PEG 6 creates a barrier on the skin's surface, which helps to reduce skin dryness by decreasing the loss of moisture. Its oily texture helps to thicken and provides a slipperiness, which helps make our lotions and natural strength deodorants easy to apply and leaves a non-greasy after-touch.PEG 6 are naturally occurring in coconut and palm kernel oils at lower levels but to make this pure ingredient, the oils are split and the specific fatty acid (capric acid and caprylic acid are isolated and recombined with the glycerin backbone to form the pure capric/caprylic triglyceride which is then further purified (bleached and deodorized) using clay, heat and steam. No other additives or processing aids are used.PEG 6 is a mixed ester composed of caprylic and capric fatty acids attached to a glycerin backbone. PEG 6 are sometimes erroneously referred to as fractionated coconut oil, which is similar in composition but typically refers to coconut oil that has had its longer chain triglycerides removed. Chemically speaking, fats and oils are made up mostly of triglycerides whose fatty acids are chains ranging from 6–12 carbon atoms, in this case the ester is comprised of capric (10 carbon atoms) and caprylic (8 carbon atoms).PEG 6 are a specialized esterification of Coconut Oil using just the Caprylic and Capric Fatty Acids, while Fractionated Coconut Oil is a, standard, distillation of Coconut Oil which results in a combination of all of the fatty acids, pulled through the distillation process. PEG 6 is non-greasy and light weight. It comes in the form of an oily liquid and mainly works as an emollient, dispersing agent and solvent.PEG 6 is a mixed triester derived from coconut oil and glycerine which comes in the form of an oily liquid, and is sometimes mistakenly referred to as fractionated coconut oil which shares a similar INCI name.It is usually used in skin care as an emollient, dispersing agent and solvent. As an emollient, it quickly penetrates the surface to condition the skin and hair, and provides a lightweight, non-greasy lubricating barrier. As a dispersing agent, it helps enhance the delivery of vitamins, pigments and active ingredients contained in a solution so that they become evenly spread and fully absorbed by the epidermis. It's oily texture thickens cosmetic formulas and provides a slipperiness, which in turn allows the easy spreadability of solutions and a smooth after-feel.Cosmetic formulators value this product for its lack of colour and odour, as well as for its stability. It has such great stability and resistance to oxidation that it has an almost indefinite shelf life.PEG 6 are a stable, oxidation-resistant esterification of plant origin. They are rapidly absorbed and are a good substitute for vegetable oils in emulsions. The product provides softness and suppleness and does not cause greasiness.They are also insoluble in water and are ideal as an additive for dry oils, emulsions, serums, creams targeted towards oily and impure skin and macerates in oil.PEG 6 – also known as MCT Oil – is a classic emollient derived from renewable natural raw materials. It is produced from vegetable Glycerine and fractionated vegetable Fatty Acids, mainly Caprylic and Capric Acids. MCT Oil is a clear and colourless liquid, neutral in odour and taste. It is fully saturated and therefore highly resistant to oxidation. Our production units, based in Germany and Malaysia, are backwards integrated into the feedstock and dedicated to the production of MCT Oils. PEG 6 is a clear liquid derived from coconut oil, which is an edible substance that comes from the coconut nut of the coconut palm tree. Coconut palms, cocos nucifera, grow around the world in lowland tropical and subtropical areas where annual precipitation is low.PEG 6 is a digestible ingredient used in hundreds of personal care and household products, such as baby wipes, lotion, makeup, deodorant, sunscreen, and hair-care items.We use PEG 6 in our products as a moisturizer. Palm oil is a common alternative, but it is an endangered resource. The Cosmetic Ingredient Review has deemed PEG 6 safe in cosmetic formulations, and the Food and Drug Administration has deemed PEG 6 as generally recognized as safe (GRAS) in food.[10] Whole Foods has deemed the ingredient acceptable in its body care quality standards.[11] Studies show that PEG 6 have very low toxicity to people and animals when eaten, injected, or put on the skin or eyes.[12] Studies also show PEG 6 is not a skin irritant.Caprylic triglyceride is the mixed triester of glycerin and caprylic and capric acids. It is made by first separating the fatty acids and the glycerol in coconut oil. This is done by hydrolyzing the coconut oil, which involves applying heat and pressure to the oil to split it apart. The acids then go through esterification to add back the glycerol. The resulting oil is called PEG 6. It has different properties from raw coconut oil.PEG 6 is produced by reacting coconut oil with glycerol through esterification. MCT Oil is not oil; it is an ester which primarily contains the Caprylic and Capric medium chain triglycerides present in the coconut oil. PEG 6 is a clear, colorless and virtually odorless liquid that dispenses quickly at room temperature as compared to its raw material coconut oil which is solid at room temperature. PEG 6 are commonly used in cosmetics as it absorbs rapidly into the skin and adds a smooth and dry oil feel to the skin. It is often used as an ingredient in cream, lotion, moisturizer, cleanser & face wash, serum, and others. PEG 6 developed around fifty years ago as an energy source for patients suffering from fat malabsorption syndrome which still finds applications in medical, nutritional products due to the purity and the unique attributes of PEG 6.

PEG 60 HYDROGENATED CASTOR OIL PEG-60 Hydrogenated Castor Oil Details A castor oil derived, white, lard-like helper ingredient that is used as a solubilizer to put fragrances (those are oil loving things) into water-based products such as toners. Is peg 60 hydrogenated castor oil safe? Is PEG-60 Hydrogenated Castor Oil Safe In Skincare Products? PEG-60 Hydrogenated Castor Oil is usually used in concentrations between 0,5% and 10%. In these small amounts, it's considered to be safe. What Is PEG-60 Hydrogenated Castor Oil? You’ve probably guessed it from the name. PEG-60 Hydrogenated Castor Oil is derived from… well, castor oil. What does it look like? It’s a white, lard-like paste. Struggling to create an anti-aging skincare routine that really works? Download your FREE “Best Anti-Aging Skincare Routine” cheatsheet below to get started. What Does PEG-60 Hydrogenated Castor Oil Do In Skincare Products? PEG-60 Hydrogenated Castor Oil has three jobs in skincare products: Surfactant: That’s a fancy way of calling a cleansing agent. It helps water mix with oil and dirt so that they can be rinsed away, leaving skin and hair both clean and soft. Emulsifier: It allows the watery and oily parts of a formula to mix together, preventing the texture from separating into two layers. Solubizing agent: It helps other ingredients to dissolve in a solvent in which they wouldn’t normally dissolve. For example, it’s used to add fragrances (which typically dissolve in oils) into water-based products. Is hydrogenated castor oil good for your skin? This makes it easier for them to be washed away and lends this ingredient popularity in facial and body cleansers. As an occlusive agent, PEG 60 Hydrogenated Castor Oil creates a protective hydrating layer on the skin's surface, acting as a barrier against the loss of natural moisture. PEG-60 HYDROGENATED CASTOR OIL PEG-60 HYDROGENATED CASTOR OIL is classified as : Emulsifying Surfactant CAS Number 61788-85-0 COSING REF No: 77219 Chem/IUPAC Name: Castor oil (Ricinus communis), hydrogenated, ethoxylated (60 mol EO average molar ratio) PEG-60 Hydrogenated Castor Oil What Is It? PEG-8 Castor Oil, PEG-9 Castor Oil, PEG-10 Castor Oil, PEG-11 Castor Oil, PEG-15 Castor Oil, PEG-16 Castor Oil, PEG-20 Castor Oil, PEG-25 Castor Oil, PEG-26 Castor Oil, PEG-29 Castor Oil, PEG-44 Castor Oil, PEG-50 Castor Oil, PEG-54 Castor Oil, PEG-55 Castor Oil, PEG-60 Castor Oil, PEG-75 Castor Oil, PEG-80 Castor Oil, PEG-100 Castor Oil and PEG-200 Castor Oil are polyethylene glycol derivatives of castor oil. PEG-8 Hydrogenated Castor Oil, PEG-10 Hydrogenated Castor Oil, PEG-16 Hydrogenated Castor Oil, PEG-20 Hydrogenated Castor Oil, PEG-25 Hydrogenated Castor Oil, PEG-35 Hydrogenated Castor Oil, PEG-45 Hydrogenated Castor Oil, PEG-50 Hydrogenated Castor Oil, PEG-54 Hydrogenated Castor Oil, PEG-55 Hydrogenated Castor Oil, PEG-60 Hydrogenated Castor Oil, PEG-65 Hydrogenated Castor Oil, PEG-80 Hydrogenated Castor Oil, PEG-100 Hydrogenated Castor Oil and PEG-200 Hydrogenated Castor Oil are polyethylene glycol derivatives of hydrogenated castor oil. In cosmetics and personal care products, the PEG Castor Oil and PEG Hydrogenated Castor Oil ingredients are used in the formulation of a wide variety of products including bath products, aftershave lotions, skin care products, cleansing products, deodorants, fragrances, makeup, hair conditioners, shampoos, hair care products, personal cleanliness products, and nail polish and enamels. Why is it used in cosmetics and personal care products? The following functions have been reported for the PEG Castor Oil and PEG Hydrogenated Castor Oil ingredients. Skin conditioning agent - emollient - PEG-8 Castor Oil, PEG-9 Castor Oil, PEG-10 Castor Oil, PEG-11 Castor Oil, PEG-15 Castor Oil, PEG-16 Castor Oil, PEG-8 Hydrogenated Castor Oil, PEG-10 Hydrogenated Castor Oil, PEG-16 Hydrogenated Castor Oil, PEG-65 Hydrogenated Castor Oil Surfactant - cleansing agent - PEG-10 Castor Oil, PEG-44 Castor Oil, PEG-50 Castor Oil, PEG-54 Castor Oil, PEG-55 Castor Oil, PEG-60 Castor Oil, PEG-80 Castor Oil, PEG-100 Castor Oil, PEG-200 Castor Oil, PEG-45 Hydrogenated Castor Oil, PEG-50 Hydrogenated Castor Oil, PEG-54 Hydrogenated Castor Oil, PEG-55 Hydrogenated Castor Oil, PEG-60 Hydrogenated Castor Oil, PEG-80 Hydrogenated Castor Oil, PEG-100 Hydrogenated Castor Oil, PEG-200 Hydrogenated Castor Oil Surfactant - emulsifying agent - PEG-8 Castor Oil, PEG-9 Castor Oil, PEG-10 Castor Oil, PEG-11 Castor Oil, PEG-15 Castor Oil, PEG-16 Castor Oil, PEG-20 Castor Oil, PEG-25 Castor Oil, PEG-26 Castor Oil, PEG-29 Castor Oil, PEG-8 Hydrogenated Castor Oil,PEG-10 Hydrogenated Castor Oil, PEG-16 Hydrogenated Castor Oil, PEG-20 Hydrogenated Castor Oil, PEG-25 Hydrogenated Castor Oil, PEG-35 Hydrogenated Castor Oil, PEG-65 Hydrogenated Castor Oil Surfactant - solubilizing agent - PEG-26 Castor Oil, PEG-29 Castor Oil, PEG-44 Castor Oil, PEG-50 Castor Oil, PEG-54 Castor Oil, PEG-55 Castor Oil, PEG-60 Castor Oil, PEG-75 Castor Oil, PEG-80 Castor Oil, PEG-100 Castor Oil, PEG-200 Castor Oil, PEG-35 Hydrogenated Castor Oil, PEG-45 Hydrogenated Castor Oil, PEG-50 Hydrogenated Castor Oil, PEG-54 Hydrogenated Castor Oil, PEG-55 Hydrogenated Castor Oil, PEG-60 Hydrogenated Castor Oil, PEG-80 Hydrogenated Castor Oil, PEG-100 Hydrogenated Castor Oil, PEG-200 Hydrogenated Castor Oil Scientific Facts: PEG Castor Oil and PEG Hydrogenated Castor Oil ingredients are produced from castor oil and hydrogenated castor oil, respectively. Castor oil is obtained by the cold pressing of seeds of the Ricinus communis plant followed by clarification of the oil by heat. PEG 60 Hydrogenated Castor Oil ALL ABOUT PEG 60 HYDROGENATED CASTOR OIL Content What is Peg 60 Hydrogenated Castor Oil? How does Peg 60 Hydrogenated Castor Oil Work?PEG 60 Hydrogenated Castor Oil SolubilityPEG 60 Hydrogenated Castor Oil UsesPEG 60 Hydrogenated Castor Oil Side Effects WHAT IS PEG 60 HYDROGENATED CASTOR OİL ? PEG 60 Hydrogenated Castor Oil is the Polyethylene Glycol derivatives of Hydrogenated Castor Oil, and it functions as a surfactant, a solubilizer, an emulsifier, an emollient, a cleansing agent, and a fragrance ingredient when added to cosmetics or personal care product formulations. NDA’s PEG 60 Hydrogenated Castor Oil is a semi-solid ingredient. HOW DOES PEG 60 HYDROGENATED CASTOR OIL WORK? PEG 60 HYDROGENATED CASTOR OİL is soluble in both water and oil and is traditionally used to emulsify and solubilize oil-in-water formulations. Its foam-enhancing properties make it ideal for use in liquid cleansers, and its soothing and softening emollient quality makes it a popular addition to formulations for moisturizers and hair care cosmetics. As a surfactant, PEG 60 Hydrogenated Castor Oil helps to decrease the surface tension between multiple liquids or between liquids and solids. Furthermore, it helps to remove the grease from oils and causes them to become suspended in the liquid. This makes it easier for them to be washed away and lends this ingredient popularity in facial and body cleansers. As an occlusive agent, PEG 60 Hydrogenated Castor Oil creates a protective hydrating layer on the skin’s surface, acting as a barrier against the loss of natural moisture. PEG 60 Hydrogenated Castor Oil SOLUBILITY When adding PEG 60 Hydrogenated Castor Oil to cosmetics formulations, it can be blended in its cold state directly into the oil phase at a suggested ratio of 3:1 (PEG 60 Hydrogenated Castor Oil to oil). Next, this can be added to the water phase. If the formula is cloudy, the amount of PEG 60 Hydrogenated Castor Oil may be increased for enhanced transparency. PEG 60 Hydrogenated Castor Oil USES PRODUCT TYPE & FUNCTION When added to this kind of formulation… Liquid Soap, Facial Cleanser, Bubble Bath, Shower Gel Face Cream, Lotion, Sunscreen Makeup, Face Mask, Skin Peel, Deodorant Shampoo, Conditioner EFFECTS PEG 60 Hydrogenated Castor Oil functions as a(n): Surfactant Solubilizer Emulsifier Emollient Cleansing Agent Fragrance Ingredient PEG 60 Hydrogenated Castor Oil helps to: Combine immiscible ingredients Gently cleanse and soothe the skin and scalp Create foam in cleansing products Offer a consistent thoroughly-blended feel to products Maintain product transparency and clarity Enhance spreadability of product on skin The recommended maximum dosage is 1-25% PEG 60 Hydrogenated Castor Oil SIDE EFFECTS As with all other New Directions Aromatics products, PEG 60 Hydrogenated Castor Oil Raw Material is for external use only. It is imperative to consult a medical practitioner before using this product for therapeutic purposes. Pregnant and nursing women as well as those with sensitive, irritated, broken, injured, or damaged skin are especially advised not to use PEG 60 Hydrogenated Castor Oil Raw Material without the medical advice of a physician. This product should always be stored in an area that is inaccessible to children, especially those under the age of 7. Prior to using PEG 60 Hydrogenated Castor Oil Raw Material, a skin test is recommended. This can be done by dissolving 1 tsp PEG 60 Hydrogenated Castor Oil Raw Material in 1 tsp of a preferred Carrier Oil and applying a dime-size amount of this blend to a small area of skin that is not sensitive. PEG 60 Hydrogenated Castor Oil must never be used near the inner nose and ears or on any other particularly sensitive areas of skin. Potential side effects of PEG 60 Hydrogenated Castor Oil include the itching, blistering, burning, and scaling of skin as well as hives. In the event of an allergic reaction, discontinue use of the product and see a doctor, pharmacist, or allergist immediately for a health assessment and appropriate remedial action. To prevent side effects, consult with a medical professional prior to use. IMPORTANT: All New Directions Aromatics (NDA) products are for external use only unless otherwise indicated. This information is not intended to diagnose, treat, cure, or prevent any disease, and it should not be used by anyone who is pregnant or under the care of a medical practitioner. Please refer to our policies for further details, and our disclaimer below. Description of PEG 60 Hydrogenated Castor Oil : Non-ionic, ethoxlyated polyethylene glycol ester made from castor oil. Off-white/yellow liquid to semi-solid. Miscible in water and oils. HLB value 15 (gives oil-in-water emulsions). pH 5.5-7 (3% in water). CAS of PEG 60 Hydrogenated Castor Oil: 61788-85-0 INCI Name of PEG 60 Hydrogenated Castor Oil: PEG 60 HYDROGENATED CASTOR OİL Benefitsof PEG 60 Hydrogenated Castor Oil: Multifunctional agent that can be used as emulsifier, surfactant and solubilizer Useful also as foam booster and solubilizer of extracts, perfumes and vitamins Use of PEG 60 Hydrogenated Castor Oil: Can be added to formulas as is, usual concentration 1 - 10%. For external use only. Applications of PEG 60 Hydrogenated Castor Oil: Universally applicable, especially in liquid soaps, lotions, body washes, shower gels, hair shampoos, facial cleansers, bubble baths, decorative cosmetics. Country of Origin of PEG 60 Hydrogenated Castor Oil: USA Raw material source: Castor oil (obtained from castor beans) Manufacture of PEG 60 Hydrogenated Castor Oil: Hydrogenation of castor oil with hydrogen gas followed by pegylation (attachment of polyethylene glycol molecules) Animal Testing of PEG 60 Hydrogenated Castor Oil: Not animal tested GMO of PEG 60 Hydrogenated Castor Oil: Not tested for GMOs Vegan of PEG 60 Hydrogenated Castor Oil: Does not contains animal-derived components PEG 60 HYDROGENATED CASTOR OİL PEG 60 HYDROGENATED CASTOR OİL is a polyethylene glycol derivative of castor oil. It has a mild fatty odor. It functions as an emulsifier, surfactant and fragrance ingredient. PEG 60 HYDROGENATED CASTOR OİL is classified as : Emulsifying Surfactant CAS Number of PEG 60 HYDROGENATED CASTOR OİL 61788-85-0 COSING REF No of PEG 60 HYDROGENATED CASTOR OİL: 78452 Chem/IUPAC Name of PEG 60 HYDROGENATED CASTOR OİL: Castor oil (Ricinus communis), hydrogenated, ethoxylated (60 mol EO average molar ratio) What is PEG 60 Hydrogenated Castor Oil? PEG 60 Hydrogenated Castor Oil is the polyethylene glycol (PEG) derivative of hydrogenated castor oil. It's uses are common in this form as an emulsifier and a fragrance ingredient.PEG 60 has the FDA-approval for external use. Studies have found PEG 60 to be safe in concentrations of up to 100%. Generally speaking, PEGs are not skin irritants. PEG 60's molecular weight of 60 means it is only minimally absorbed into the skin.However, there is quite a bit of controversy over the safety of PEG 60. While the FDA approved it for external use, the Cosmetics Database found it to be moderately hazardous. According to the database, contamination is possible with potentially toxic impurities. Studies show that applying products containing PEG 60 to severe burns can result in kidney toxicity. So never apply to broken skin due to the risk of organic toxicity.How can PEG 60 be so toxic when absorbed by the body when pure castor oil is so safe? To understand that, we need to look at the scientific process of ethoxylation.PEG 60 is a result of the ethoxylation process. When hydrogenated castor oil is ethoxylated with ethylene oxide, which is a petroleum-based chemical, the process may introduce the carcinogen 1,4 dioxane as a contaminant. It also may not. This is a possibility each time the ethoxylation process occurs. However, it is not a guarantee that the product result is without contamination.PEG 60 Hydrogenated Castor Oil is the polyethylene glycol derivatives of hydrogenated castor oil, and is an amber colored, slightly viscous liquid that has a naturally mildly fatty odor. It is used in cosmetics and beauty products as an emulsifier, surfactant, and fragrance ingredient, according to research.PEG Castor Oils and PEG Hydrogenated Castor Oils are a family of polyethylene glycol derivatives of castor oil and hydrogenated castor oil that are used in over 500 formulations representing a wide variety of cosmetic products. They are used as skin conditioning agents and as surfactants (emulsifying and or solubilizing agents). The PEG Castor Oils and PEG Hydrogenated Castor Oils include various chain lengths, depending on the quantity of ethylene oxide used in synthesis. Although not all polymer lengths have been studied, it is considered acceptable to extrapolate the results of the few that have been studied to allingredients in the family. Because a principal noncosmetic use of PEG Castor Oils is as solvents for intravenous drugs, clinical data are available that indicate intravenous exposure can result in cardiovascular changes. Results from animal studies indicate very high LD50 values, with some evidence of acute nephrotoxicity in rats but not in rabbits. Short-term studies with intravenous exposure produced some evidence of toxicity in dogs but not in rabbits. Intramusuclar injection produced no toxicity in several species, including dogs. Subchronic oral studies also were negative. No dermal or ocular irritation was observed in studies in rabbits. Irritation was seen during induction, but no sen-sitization was found on challenge in guinea-pig studies using up to 50% PEG-35 Castor Oil; however, thisingredient was found to be a potent adjuvant in guinea pigs and mice. No evidence of developmental toxicity was seen in mice and rat feeding studies. Theseingredients, tested as vehicle controls, produced no mutagenic or carcinogenic effect. Clinical data are generally negative for irritation and sensitization, although some anaphylactoid reactions have been seen in studies of intravenous drugs in which PEG-35 Castor Oil was used as the vehicle. Because the maximum concentration used in animal sensitization studies was 50% for PEG Castor Oils and 100% for PEG Hydrogenated Castor Oils, it was concluded that PEG Castor Oils are safe for use in cosmetic formulations up to a concentration of 50% and that PEG Hydrogenated Castor Oils are safe as used in cosmetic formulations.t's a non-ionic surfactant that behaves as a foam booster and solubilizer of oils in water based products. (Unlike some other solubilizers, it won't suppress foam. Yay!) It can be used in the heated phase or the cool down phase of a product at up to 100%. Castor Oil Ethoxylates have many uses, primarily as nonionic surfactants in various formulations both, industrial & domestic. These are also used as cleaning agents, antistatic agents, dispersants or emulsifiers, defoamers, softeners in textile formulations. Also these are used as emulsifiers, solubalizers in cosmetics , health care & agrochemical formulations. Castor oil ethoxylates are a type of nonionic vegetable oil ethoxylate based on castor oil which is composed of traditional fatty acids like stearic acid but also the unique ricinoleic acid.The ethoxylates act as the emulsifier, solubilizers, anti-static agents, and lubricants in various market segments including home care, personal care, and agrochemicals.

Polyethylene glycol 600; Poly(ethylene glycol) ; PEG; Macrogol; Polyoxyethlene; Aquaffin; Nycoline; alpha-hydro-omega-hydroxypoly(oxy-1,2-ethanediyl); polyethylene glycols; Poly Ethylene Oxide; Polyoxyethylene; Polyglycol; 1,2-ethanediol Ehoxylated; Polyoxyethylene ether; Polyoxyethylene; Poly(ethylene glycol); cas no:25322-68-3

cas no 9004-96-0 Polyethylene glycol 600 monooleate acid ester; PEG(14) monooleate; PEG600MO; PEG(14)MO;

PEG, Poly(ethylene glycol), peg 6000, cas no : 25322-68-3; PEG, Polymère d'oxyéthylène, alpha-hydro-oméga-hydroxypoly(oxy-1,2-éthynediyl),poly(oxyde d'éthylène), poly(oxyéthylène), PEG, PEO, No Cas: 25322-68-3; PEG, Polymère d'oxyéthylène,alpha-hydro-oméga-hydroxypoly(oxy-1,2-éthynediyl),poly(oxyde d'éthylène), poly(oxyéthylène), PEG, PEO, Le PEG est utilisé dans de nombreux secteurs de l'industrie. Il sert par exemple comme épaississant ou gélifiant à la base de nombreux produits cosmétiques (savons liquides, crèmes hydratantes, shampoings, etc.) et paramédicaux (gels hydroalcooliques, lubrifiants intimes, etc.). Il est également utilisé comme solvant dans les encres pour imprimantes ou pour fabriquer des billes de paint-ball, ou bien comme additif alimentaire et dans certaines résines polyesters.Poly(ethylene glycol), Poly(oxy-1,2-ethanediyl),.alpha.-hydro-.omega.-hydroxy; Poly(oxy-1,2-ethanediyl),α-hydro-ω-hydroxy- Ethane-1,2-diol; Poly(oxy-1,2-ethanediyl),α-hydro-ω-hydroxy-Ethane-1,2-diol, ethoxylated;poly(oxyethylene); POLYETHYLENE GLYCOL

Polyethylene glycol 6000; Poly(ethylene glycol) ; PEG; Macrogol; Polyoxyethlene; Aquaffin; Nycoline; alpha-hydro-omega-hydroxypoly(oxy-1,2-ethanediyl); polyethylene glycols; Poly Ethylene Oxide; Polyoxyethylene; Polyglycol; 1,2-ethanediol Ehoxylated; Polyoxyethylene ether; Polyoxyethylene; Poly(ethylene glycol); cas no:25322-68-3

PEG 6000 Powder Polyethylene glycol (PEG 6000 powder; /ˌpɒliˈɛθəlˌiːn ˈɡlaɪˌkɒl, -ˌkɔːl/) is a polyether compound with many applications, from industrial manufacturing to medicine. PEG 6000 powder is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight. The structure of PEG 6000 powder is commonly expressed as H−(O−CH2−CH2)n−OH. Uses of Polyethylene glycol (PEG 6000 powder Medical uses of Polyethylene glycol (PEG 6000 powder) Main article: Macrogol PEG 6000 powder is the basis of a number of laxatives.[4] Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy. PEG 6000 powder is also used as an excipient in many pharmaceutical products. When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood.[5] The possibility that PEG 6000 powder could be used to fuse axons is being explored by researchers studying peripheral nerve and spinal cord injury.[4] Chemical uses of Polyethylene glycol (PEG 6000 powder) The remains of the 16th century carrack Mary Rose undergoing conservation treatment with PEG 6000 powder in the 1980s Terra cotta warrior, showing traces of original color Because PEG 6000 powder is a hydrophilic molecule, it has been used to passivate microscope glass slides for avoiding non-specific sticking of proteins in single-molecule fluorescence studies.[6] Polyethylene glycol has a low toxicity and is used in a variety of products.[7] The polymer is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments.[8] Since PEG 6000 powder is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures (on the order of tens of atmospheres). It also is unlikely to have specific interactions with biological chemicals. These properties make PEG 6000 powder one of the most useful molecules for applying osmotic pressure in biochemistry and biomembranes experiments, in particular when using the osmotic stress technique. Polyethylene glycol is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers. PEG 6000 powder has also been used to preserve objects that have been salvaged from underwater, as was the case with the warship Vasa in Stockholm,[9] and similar cases. It replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.[4] In addition, PEG 6000 powder is used when working with green wood as a stabilizer, and to prevent shrinkage.[10] PEG 6000 powder has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China.[11] These painted artifacts were created during the Qin Shi Huang (first emperor of China) era. Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xi'an air. The paint would subsequently flake off in about four minutes. The German Bavarian State Conservation Office developed a PEG 6000 powder preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.[12] PEG 6000 powder is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning. PEG 6000 powder derivatives, such as narrow range ethoxylates, are used as surfactants. PEG 6000 powder has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.[13] PEG 6000 powder has also been used as a propellent on the UGM-133M Trident II Missile, in service with the United States Air Force.[14] Biological uses PEG 6000 powder is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.[6] PEG 6000 powder is commonly used as a precipitant for plasmid DNA isolation and protein crystallization. X-ray diffraction of protein crystals can reveal the atomic structure of the proteins. PEG 6000 powder is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas. Polymer segments derived from PEG 6000 powder polyols impart flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam cushions. In microbiology, PEG 6000 powder precipitation is used to concentrate viruses. PEG 6000 powder is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro. Gene therapy vectors (such as viruses) can be PEG 6000 powder-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect.[15] The size of the PEG 6000 powder polymer has been shown to be important, with larger polymers achieving the best immune protection. PEG 6000 powder is a component of stable nucleic acid lipid particles (SNALPs) used to package siRNA for use in vivo.[16][17] In blood banking, PEG 6000 powder is used as a potentiator to enhance detection of antigens and antibodies.[4][18] When working with phenol in a laboratory situation, PEG 6000 powder 300 can be used on phenol skin burns to deactivate any residual phenol (some references are required). In biophysics, polyethylene glycols are the molecules of choice for the functioning ion channels diameter studies, because in aqueous solutions they have a spherical shape and can block ion channel conductance.[19][20] Commercial uses PEG 6000 powder is the basis of many skin creams (as cetomacrogol) and personal lubricants (frequently combined with glycerin). PEG 6000 powder is used in a number of toothpastes[4] as a dispersant. In this application, it binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste. PEG 6000 powder is also under investigation for use in body armor, and in tattoos to monitor diabetes.[21][22] In low-molecular-weight formulations (e.g. PEG 6000 powder 400), it is used in Hewlett-Packard designjet printers as an ink solvent and lubricant for the print heads. PEG 6000 powder is also used as an anti-foaming agent in food and drinks[23] – its INS number is 1521[24] or E1521 in the EU.[25] Industrial uses A nitrate ester-plasticized polyethylene glycol (NEPE-75) is used in Trident II submarine-launched ballistic missile solid rocket fuel.[26] Dimethyl ethers of PEG 6000 powder are the key ingredient of Selexol, a solvent used by coal-burning, integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the gas waste stream. PEG 6000 powder has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.[27] PEG 6000 powder is also used as a polymer host for solid polymer electrolytes. Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving PEG 6000 powder, with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future. PEG 6000 powder is injected into industrial processes to reduce foaming in separation equipment. PEG 6000 powder is used as a binder in the preparation of technical ceramics.[28] Recreational uses PEG 6000 powder is used to extend the size and durability of very large soap bubbles. PEG 6000 powder is the main ingredient in many personal lubricants. Health effects PEG 6000 powder is considered biologically inert and safe by the FDA. However, a growing body of evidence shows the existence of anti PEG 6000 powder antibodies in approximately 72% of the population based on plasma samples from 1990–1999.[medical citation needed] The FDA has been asked to investigate the possible effects of PEG 6000 powder in laxatives for children.[29] Due to its ubiquity in a multitude of products and the large percentage of the population with antibodies to PEG 6000 powder, hypersensitive reactions to PEG 6000 powder are an increasing concern.[medical citation needed] Allergy to PEG 6000 powder is usually discovered after a person has been diagnosed with an allergy to an increasing number of seemingly unrelated products, including processed foods, cosmetics, drugs, and other substances that contain PEG 6000 powder or were manufactured with PEG 6000 powder.[30] When PEG 6000 powder is chemically attached to therapeutic molecules (such as protein drugs or nanoparticles), it can sometimes be antigenic, stimulating an anti-PEG 6000 powder antibody response in some patients. This effect has only been shown for a few of the many available PEG 6000 powderylated therapeutics, but it has significant effects on clinical outcomes of affected patients.[31] Other than these few instances where patients have anti-PEG 6000 powder immune responses, it is generally considered to be a safe component of drug formulations. Available forms and nomenclature PEG 6000 powder, PEO, and POE refer to an oligomer or polymer of ethylene oxide. The three names are chemically synonymous, but historically PEG 6000 powder is preferred in the biomedical field, whereas PEO is more prevalent in the field of polymer chemistry. Because different applications require different polymer chain lengths, PEG 6000 powder has tended to refer to oligomers and polymers with a molecular mass below 20,000 g/mol, PEO to polymers with a molecular mass above 20,000 g/mol, and POE to a polymer of any molecular mass.[32] PEG 6000 powders are prepared by polymerization of ethylene oxide and are commercially available over a wide range of molecular weights from 300 g/mol to 10,000,000 g/mol.[33] PEG 6000 powder and PEO are liquids or low-melting solids, depending on their molecular weights. While PEG 6000 powder and PEO with different molecular weights find use in different applications, and have different physical properties (e.g. viscosity) due to chain length effects, their chemical properties are nearly identical. Different forms of PEG 6000 powder are also available, depending on the initiator used for the polymerization process – the most common initiator is a monofunctional methyl ether PEG 6000 powder, or methoxypoly(ethylene glycol), abbreviated mPEG 6000 powder. Lower-molecular-weight PEG 6000 powders are also available as purer oligomers, referred to as monodisperse, uniform, or discrete. Very high purity PEG 6000 powder has recently been shown to be crystalline, allowing determination of a crystal structure by x-ray diffraction.[33] Since purification and separation of pure oligomers is difficult, the price for this type of quality is often 10–1000 fold that of polydisperse PEG 6000 powder. PEG 6000 powders are also available with different geometries. Branched PEG 6000 powders have three to ten PEG 6000 powder chains emanating from a central core group. Star PEG 6000 powders have 10 to 100 PEG 6000 powder chains emanating from a central core group. Comb PEG 6000 powders have multiple PEG 6000 powder chains normally grafted onto a polymer backbone. The numbers that are often included in the names of PEG 6000 powders indicate their average molecular weights (e.g. a PEG 6000 powder with n = 9 would have an average molecular weight of approximately 400 daltons, and would be labeled PEG 6000 powder 400.) Most PEG 6000 powders include molecules with a distribution of molecular weights (i.e. they are polydisperse). The size distribution can be characterized statistically by its weight average molecular weight (Mw) and its number average molecular weight (Mn), the ratio of which is called the polydispersity index (Mw/Mn). Mw and Mn can be measured by mass spectrometry. PEG 6000 powderylation is the act of covalently coupling a PEG 6000 powder structure to another larger molecule, for example, a therapeutic protein, which is then referred to as a PEG 6000 powderylated protein. PEG 6000 powderylated interferon alfa-2a or −2b are commonly used injectable treatments for hepatitis C infection. PEG 6000 powder is soluble in water, methanol, ethanol, acetonitrile, benzene, and dichloromethane, and is insoluble in diethyl ether and hexane. It is coupled to hydrophobic molecules to produce non-ionic surfactants.[34] PEG 6000 powders potentially contain toxic impurities, such as ethylene oxide and 1,4-dioxane.[35] Ethylene Glycol and its ethers are nephrotoxic if applied to damaged skin.[36] Polyethylene oxide (PEO, Mw 4 kDa) nanometric crystallites (4 nm) Polyethylene glycol (PEG 6000 powder) and related polymers (PEG 6000 powder phospholipid constructs) are often sonicated when used in biomedical applications. However, as reported by Murali et al., PEG 6000 powder is very sensitive to sonolytic degradation and PEG 6000 powder degradation products can be toxic to mammalian cells. It is, thus, imperative to assess potential PEG 6000 powder degradation to ensure that the final material does not contain undocumented contaminants that can introduce artifacts into experimental results.[37] PEG 6000 powders and methoxypolyethylene glycols are manufactured by Dow Chemical under the tradename Carbowax for industrial use, and Carbowax Sentry for food and pharmaceutical use. They vary in consistency from liquid to solid, depending on the molecular weight, as indicated by a number following the name. They are used commercially in numerous applications, including as surfactants, in foods, in cosmetics, in pharmaceutics, in biomedicine, as dispersing agents, as solvents, in ointments, in suppository bases, as tablet excipients, and as laxatives. Some specific groups are lauromacrogols, nonoxynols, octoxynols, and poloxamers. Macrogol, used as a laxative, is a form of polyethylene glycol. The name may be followed by a number which represents the average molecular weight. Production of Polyethylene glycol (PEG 6000 powder) Polyethylene glycol 400, pharmaceutical quality Polyethylene glycol 4000, pharmaceutical quality The production of polyethylene glycol was first reported in 1859. Both A. V. Lourenço and Charles Adolphe Wurtz independently isolated products that were polyethylene glycols.[38] Polyethylene glycol is produced by the interaction of ethylene oxide with water, ethylene glycol, or ethylene glycol oligomers.[39] The reaction is catalyzed by acidic or basic catalysts. Ethylene glycol and its oligomers are preferable as a starting material instead of water, because they allow the creation of polymers with a low polydispersity (narrow molecular weight distribution). Polymer chain length depends on the ratio of reactants. HOCH2CH2OH + n(CH2CH2O) → HO(CH2CH2O)n+1H Depending on the catalyst type, the mechanism of polymerization can be cationic or anionic. The anionic mechanism is preferable because it allows one to obtain PEG 6000 powder with a low polydispersity. Polymerization of ethylene oxide is an exothermic process. Overheating or contaminating ethylene oxide with catalysts such as alkalis or metal oxides can lead to runaway polymerization, which can end in an explosion after a few hours. Polyethylene oxide, or high-molecular weight polyethylene glycol, is synthesized by suspension polymerization. It is necessary to hold the growing polymer chain in solution in the course of the polycondensation process. The reaction is catalyzed by magnesium-, aluminium-, or calcium-organoelement compounds. To prevent coagulation of polymer chains from solution, chelating additives such as dimethylglyoxime are used. Alkaline catalysts such as sodium hydroxide (NaOH), potassium hydroxide (KOH), or sodium carbonate (Na2CO3) are used to prepare low-molecular-weight polyethylene glycol. Polyethylene glycol (PEG 6000 powder) is a versatile polyether being utilized in various applications, in particular in medicine. Polyethylene oxide (PEO) is another name for PEG 6000 powder. Typically, ethylene oxide macromolecules (Fig. 18.9) with molecular weights less than 20,000 g/mol are called PEG 6000 powder, while those having values above 20,000 g/mol are named PEO. It is reported that PEG 6000 powder is soluble in water, ethanol, acetonitrile, benzene, and dichloromethane, while it is insoluble in diethyl ether and hexane. PEG 6000 powder is available in different structures such as branched, star, and comb-like macromolecules. PEG 6000 powderylation is an attractive process in which PEG 6000 powder is bonded to another molecule, which is promising in therapeutic methods. PEG 6000 powder can hinder the protein adsorption which is essential in drug delivery to minimize the protein corona formation [29]. Polyethylene glycol (PEG 6000 powder) is a hydrophilic polymer of ethylene oxide. The non-immunogenic, biocompatible and flexible nature of PEG 6000 powder makes it a suitable synthetic dressing material for wound healing. The low toxic PEG 6000 powder macromers are well bonded with growth factor like EGF and can be delivered at the wound site [98]. The mechanical stability of PEG 6000 powder can be enhanced by blending PEG 6000 powder with chitosan and PLGA. Blending also increases thermal stability and crystallinity of the particular polymer [99]. Such PEG 6000 powder-based dressings have been widely used to treat a diabetic wound by promoting and inducing growth of skin cells and collagen deposition. It also reduces scar formation [100]. The injectable hybrid hydrogel dressing system is developed from PEG 6000 powder-based hyperbranched multiacrylated co-polymer and HA in combination with adipose-derived stem cells to support the viability of cells in vitro and in vivo. It prevents wound contraction and enhances angiogenesis by acting as temporary hydrogel for wound healing purpose [101]. Hydrophilic Materials Based on Polyethylene Glycol Polyethylene glycol (PEG 6000 powder) is the most relevant antifouling polymer in biomedical devices. PEG 6000 powder antifouling properties are thought to be related to surface hydration and steric hindrance effects (Chen et al., 2010). PEG 6000 powder chains linked to a material surface assume a brush-like configuration at the water/surface interface, limiting the approach to the surface by bacteria. Compression of the highly hydrated layer of PEG 6000 powder chains is unfavorable because it would involve a reduction in PEG 6000 powder chain mobility and removal of water molecules. Surface packing density and polymer chain length can be used to control PEG 6000 powder antifouling properties (Roosjen et al., 2004). PEG 6000 powder-functionalized PUs were developed by PEG 6000 powder introduction either in the polymer backbone (Corneillie et al., 1998) or polymer side chain (Francolini et al., 2019). Auto-oxidization in the presence of oxygen, metal ions, and enzymes able to oxidize PEG 6000 powder hydroxyl groups, however, may limit long-term effectiveness. Polyethylene glycol (PEG 6000 powder) is another important type of PCM for textile applications. The repeating unit in PEG 6000 powder is oxyethylene (–O–CH2–CH2–) containing hydroxyl group on either side of the chain. The melting point of PEG 6000 powder depends on its molecular weight and is proportional as the molecular weight increases. The phase-change temperature of PEG 6000 powder can be determined using DSC (Pielichowski and Flejtuch, 2002). PEG 6000 powder with degree of polymerization 1000 has phase-change temperature of 35°C, while PEG 6000 powder with degree of polymerization 20,000 has melting temperature of 63°C (Craig and Newton, 1991; Hopp et al., 2000). Jiang et al. (2016) synthesized a dual-functional magnetic microcapsules containing a PCM core and an organo-silica shell for the electromagnetic shielding and thermal regulating applications. Fig. 20.6 shows the resulting DSC curves where the areas under the peaks indicate the amount of latent heat contained using different organosilanes/PEG 6000 powder weight ratios. PEG 6000 powder is the basis of a number of laxatives.[3] Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy. PEG 6000 powder is also used as an excipient in many pharmaceutical products. When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood.[4] The possibility that PEG 6000 powder could be used to fuse nerve cells is being explored by researchers studying spinal cord injury.[3] Chemical uses The remains of the 16th century carrack Mary Rose undergoing conservation treatment with PEG 6000 powder in the 1980s Terra cotta warrior, showing traces of original color Because PEG 6000 powder is a hydrophilic molecule, it has been used to passivate microscope glass slides for avoiding non-specific sticking of proteins in single-molecule fluorescence studies.[5] Polyethylene glycol has a low toxicity and is used in a variety of products.[6] The polymer is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments.[7] Since PEG is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures (on the order of tens of atmospheres). It also is unlikely to have specific interactions with biological chemicals. These properties make PEG 6000 powder one of the most useful molecules for applying osmotic pressure in biochemistry and biomembranes experiments, in particular when using the osmotic stress technique. Polyethylene glycol is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers. PEG 6000 powder has also been used to preserve objects that have been salvaged from underwater, as was the case with the warship Vasa in Stockholm,[8] and similar cases. It replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.[3] In addition, PEG 6000 powder is used when working with green wood as a stabilizer, and to prevent shrinkage.[9] PEG has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China.[10] These painted artifacts were created during the Qin Shi Huang Di dynasty (first emperor of China). Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xian air. The paint would subsequently flake off in about four minutes. The German Bavarian State Conservation Office developed a PEG 6000 powder preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.[11] PEG 6000 powder is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning. PEG 6000 powder derivatives, such as narrow range ethoxylates, are used as surfactants. PEG 6000 powder is a polyol and can be reacted with an isocyanate to make polyurethane. PEG 6000 powder has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.[12] Biological uses PEG 6000 powder is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions. PEG 6000 powder is commonly used as a precipitant for plasmid DNA isolation and protein crystallization. X-ray diffraction of protein crystals can reveal the atomic structure of the proteins. PEG is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas. César Milstein and Georges J. F. Köhler originated this technique, which they used for antibody production, winning a Nobel Prize in Physiology or Medicine in 1984.[3] Polymer segments derived from PEG polyols impart flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam cushions. In microbiology, PEG 6000 powder precipitation is used to concentrate viruses. PEG is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro. Gene therapy vectors (such as viruses) can be PEG-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect.[13] The size of the PEG polymer has been shown to be important, with larger polymers achieving the best immune protection. PEG is a component of stable nucleic acid lipid particles (SNALPs) used to package siRNA for use in vivo. In blood banking, PEG is used as a potentiator to enhance detection of antigens and antibodies.[3][16] When working with phenol in a laboratory situation, PEG 300 can be used on phenol skin burns to deactivate any residual phenol. In biophysics, polyethylene glycols are the molecules of choice for the functioning ion channels diameter studies, because in aqueous solutions they have a spherical shape and can block ion channel conductance. What is Polyethyleneglycol? Polyethyleneglycol, or PEG 6000 powder for short, is a polyether consisting of a (-O-CH2-CH2-) backbone that is commonly used in many fields of academic research, industrial processing and commercial applications. PEG 6000 powders can also commonly be referred to as polyoxyethylene (POE) and polyethyleneoxide (PEO), but regardless of the name that is used, the simple structure of PEG 6000 powders (which consists of solely carbon, hydrogen and oxygen, see image below) affords safe compounds that are used throughout everyday life. Additionally, it is this simple structure that separates PEG 6000 powders from similar compounds like propylene glycol and polypropyleneglycol. The two aforementioned compounds (polyethyleneglycol vs. propylene glycol) are derivatives of propylene oxide, which, when polymerized, bestows a completely different set of physical characteristics to the compound as compared to PEG 6000 powder. The method in which PEG 6000 powders are created allows for a wide variability in their physical attributes, allowing them to be utilized by many commercial markets. By controlling a PEG 6000 powder’s size (i.e. molecular weight) and its size distribution, a wide variety of physical properties can be achieved, which sets Oxiteno’s line of PEG 6000 powder products, the 6000 powder series, apart from other name brands of polyethyleneglycols. Due to the vast number of product types offered 6000 powder products (click here for a full listing), many physical forms (liquids, pastes, solids, flakes, powder, etc.) and viscosities of PEG 6000 powders are available. It is the numerous attributes of PEG 6000 powders that allow for their inclusion in a vast array of applications, ranging from the pharmaceutical industry to cosmetic markets. While the structure of PEG 6000 powder is simple, it is this compound’s solubility in water is what makes it such a versatile additive to enhance many industrial applications. Because line of PEG 6000 powder products are non-toxic and hydrophilic (water-loving), these polymers are used in the home (i.e. to treat surfaces in cleaning agents made by cleaning chemicals manufacturers) as well as in the food production industry (to reduce the amount of foam during the processing of food products). PEG 6000 powders are generally considered to be biologically inert, making them safe to use throughout the medical and food-processing industries. What is Polyethyleneglycol Used For? Due to the variety of physical properties that can be achieved through PEG 6000 powder series, formulators in nearly all industries can benefit from this line of PEG 6000 powder products. A PEG 6000 powder’s unique ability to enhance a dye’s solubility in aqueous formulations causes it to be used throughout the textile industry as dye carriers. PEG 6000 powders are also exceptional at retaining moisture in complex formulations, as well as to an applied surface, making them excellent humectants and anti-caking agents for cosmetic chemical suppliers and coatings chemical suppliers. This unique relationship with water is further exploited by many other markets as PEG 6000 powders can help to stabilize emulsions and act as water-miscible co-solvents for aqueous formulations. The food industry uses these compounds as additives to reduce the amount of foam during food processing. Additionally, PEG 6000 powders find themselves very useful in the pharmaceutical industry due to their ability to act as rheological modifiers, thus being used as excipients. New research techniques are increasingly incorporating PEG 6000 powder compounds via the use of ‘PEG 6000 powderylation’ onto protein and peptide therapeutics, thus improving their pharmacokinetics and leading to safer and more effective drugs1-2. Many of PEG 6000 powder series meet the requirements set forth by the National Formulary (NF) guidelines for safe preparation, manufacture and use of a variety of PEG 6000 powder compounds that can be used as excipients, botanicals and other similar products. Is Polyethyleneglycol Safe? PEG 6000 powders are generally considered to be a biologically inert substance, meaning that this class of oligomers and polymers are recognized to be safe for use in food, cosmetic and pharmaceutical applications. So, is polyethyleneglycol toxic? Due to the PEG 6000 powder’s structure and its water solubility, these compounds are generally considered to be non-toxic, as studies of demonstrated their safety for use within the field of drug delivery1-2, for application to the skin in cosmetics3 and as additives in the food and vitamin processing industry4. Where applicable, line of PEG 6000 powders, 6000 powder, adhere to the guidelines for the manufacturing set forth by the National Formulary (NF). Having initially been established by the U.S. Federal Food, Drug, and Cosmetics Act of 1938, these guidelines are currently recognized by the U.S. Food and Drug Administration (FDA). These manufacturing and production guidelines are annually reviewed, requiring to not only adhere to these strict standards, but maintain constant surveillance over the preparation of these non-toxic additives. Additionally, many of PEG 6000 powder products that are used in agricultural applications are safe for the environment and are on the Environmental Protection Agencies’ (EPA) inert ingredient list, meeting the requirements set forth in 40 CFR 180.910 and 40 CFR 180.930. This makes PEG 6000 powders attractive for agrochemical companies.

PEG 6000 Distearate (peg-150 distearate) is a polyethylene glycol diester of stearic acid.
PEG 6000 Distearate (peg-150 distearate) is an off-white flake
PEG 6000 Distearate (peg-150 distearate) is a white to yellowish pellets.


CAS Number: 9005-08-7
EINECS: Polymer Exempt
MDL Number: MFCD00081839
INCI Name: PEG-150 Distearate
EINECS: Polymer Exempt
Chem/IUPAC Name: Poly (oxy-1,2-ethanediyl),. alpha. -(1-oxooctadecyl)-. omega. -[(1-oxooctadecyl)oxy]-
Molecular Formula : C19H40O4


Macrogol 6000, Polyethylenglycol 6000, Polyethylenglykol 6000 Distearat, Polyoxyethylen(150), Polyoxyethylen(150)distearat, THOX P-6000 DS, PEG-150 DISTEARATE, PEG-150 DISTEARATE [II], PEG-150 DISTEARATE [INCI], POLYETHYLENE GLYCOL 6000 DISTEARATE, POLYOXYL 150 DISTEARATE, UNIPEG-6000 DS, PEG-150 DISTEARATE, POE (150) DISTEARATE, KESSCO PEG 6000 DISTEARATE, Glycols,polyethylene, distearate (8CI), Stearic acid, diester with polyethylene glycol(8CI), 62S, 62S (lubricant), Aculyn 60, Atlas G 1821, CDS 400, CDS 6000P, CRL1095, Cithrol 10DS, Cithrol 4DS, Cithrol 60DS, Cutina TS, Cyclo PEG (400)DS, Dispeg 200, EL 1821, Emalex 200di-S, Emalex 600di-S, Emalex di-S, Emanon 3299, Emanon 3299R, Emanon 3299RV, Emanon 3299V, Emerest 2642, Emerest 2712, Emulgen3299, Emulmin 862, Estol 3734, Estol EO 4DS3724, Eumulgin EO 33, Gelucire55/18, Genapol TS Powder, Hetoxamate 6000, Hetoxamate 6000DS, Hetoxamate 6000DSSpecial, Ionet DS 1000, Ionet DS 300, Ionet DS 400, Ionet DS 4000, Kessco PEG400DS, Kessco PEG 6000DS, Lionon DT 600S, Lipal 15DS, Lipal 400DS, Lipopeg 4DS, Lipopeg 6000DS, Mapeg 1540DS, Mapeg 400DS, Mapeg 6000DS, Mazol 6000DS, NikkolCDS 6000P, Nissan Nonion DS 60HN, Noigen DS 601, Nonex 80, Nonion DS 60HN, Nonisol 300, PEG 150 distearate, PEG 1540 distearate, PEG 1540DS, PEG 6000distearate, PEG 6000DS, PEG 8 distearate, PEG distearate, PEG-2 Distearate, PEG-20 Distearate, Pegnol PDS 60, Pegosperse 400DS, Pionin D 2410D, Poly(oxyethylene) distearate, Polyethylene glycol dioctadecanoate, Polyethyleneglycol distearate, Polyethylene glycol distearoyl ester, Polyethylene glycolstearic acid diester, Polyethylene oxide distearate, Rewopal PEG 6000DS, Ritapeg 150DS, S 1009, S 1013, Stabogel, Polyethylene glycol distearate, PEG400 Distearate, heptadecanoic acid - ethane-1,2-diol (1:1), PEG 6000 Distearate Powder, PEG 6000 Distearate, Unipeg 6000DS, Lipopeg 6000 DS, Protamate 6000 DS, T/N: Lumulse 602-S, T/N: Acipol Di 15018 B, Polyethylene glycol distearate, Polyoxyethylene Distearate ester, POE(150) Distearate, Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-[(1-oxooctadecyl)oxy]-



PEG 6000 Distearate (peg-150 distearate) is a hydrophilic emulsifier; thickener.
PEG 6000 Distearate (peg-150 distearate) is an efficient thickening agent for shampoos, body washes or foam baths.
Even at low levels, PEG 6000 Distearate (peg-150 distearate) results in a high viscosity modifying effect.


PEG 6000 Distearate (peg-150 distearate) is a polyethylene glycol diester of stearic acid.
PEG 6000 Distearate (peg-150 distearate) is an off-white flake
PEG 6000 Distearate (peg-150 distearate) is a white to yellowish pellets.


This thickening agent, PEG 6000 Distearate (peg-150 distearate), has garnered appreciation for its widespread use in personal care products, cosmetics, paints, and dyes.
PEG 6000 Distearate (peg-150 distearate) is produced by the esterification of stearic acid which is derived from palm kernel oil or other vegetable oils.


PEG 6000 Distearate (peg-150 distearate) is polyethylene glycol diester of stearic acid.
PEG 6000 Distearate (peg-150 distearate) is a thickening agent.
PEG 6000 Distearate (peg-150 distearate) is easy to handle and shows distinctive viscosity modifying effects.


PEG 6000 Distearate (peg-150 distearate) is an ester made from the reaction of vegetable-derived triple-pressed grade stearic acid and a defined high molecular weight polyethylene glycol.
PEG 6000 Distearate (peg-150 distearate) is a white to off-white powder.


PEG 6000 Distearate (peg-150 distearate) is an ester made from the reaction of vegetable-derived triple-pressed grade stearic acid and a defined high molecular weight polyethylene glycol.
PEG 6000 Distearate (peg-150 distearate) is particularly effective for the thickening of clear, mild, amphoteric-containing surfactant systems, such as shampoos, body washes, bubble baths, baby baths, vapor baths, and shower gels.


PEG 6000 Distearate (peg-150 distearate) is an emulsifying agent (O/W) and thickener (aqueous).
PEG 6000 Distearate (peg-150 distearate) is an ester made from the reaction of vegetable-derived triple-pressed grade stearic acid and a defined high molecular weight polyethylene glycol.


PEG 6000 Distearate (peg-150 distearate) is an ester made from the reaction of vegetable-derived triple-pressed grade stearic acid and a defined high molecular weight polyethylene glycol.
PEG 6000 Distearate (peg-150 distearate) is a polyether compound that is used in a wide variety of fields including pharmaceutical manufacturing as an excipient and active ingredient.


PEG 6000 Distearate (peg-150 distearate) is an ester made from the reaction of vegetable-derived triple-pressed grade stearic acid and a defined high molecular weight polyethylene glycol.



USES and APPLICATIONS of PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
PEG 6000 Distearate (peg-150 distearate) is used thickening agent for cleansing formulations, especially shampoo, shower and bath preparations.
PEG 6000 Distearate (peg-150 distearate) is used Antiperspirants & Deodorants, Baby Care and Cleansing, Face Cleansing, Liquid Soap, Shampoo, and Shower/Bath Products.


PEG 6000 Distearate (peg-150 distearate) is a non-ionic surfactant with low irritation to the skin and eyes with excellent thickening power, in addition to acting positively on foam formation and increasing the viscosity response of other surfactants in the formulations.
This thickening agent, PEG 6000 Distearate (peg-150 distearate) has garnered appreciation for its widespread use in personal care products, cosmetics, paints, and dyes.


PEG 6000 Distearate (peg-150 distearate) is produced by the esterification of stearic acid which is derived from palm kernel oil or other vegetable oils.
PEG 6000 Distearate (peg-150 distearate) is an ester made from the reaction of triple pressed stearic acid and polyethylene glycol.
PEG 6000 Distearate (peg-150 distearate) is commonly used to thicken mild, amphoteric-containing surfactant systems, such as baby shampoos, lotions, pet shampoos, bubble baths, cleansing products, and hair conditioners.


PEG 6000 Distearate (peg-150 distearate) is recommended for baby-, mild hair- & shower shampoos, foam baths and skin cleansing lotions.
The shelf life of PEG 6000 Distearate (peg-150 distearate) is 12 months.
PEG 6000 Distearate (peg-150 distearate) is particularly effective for the thickening of clear, mild, amphoteric-containing surfactant systems, such as shampoos, body washes, bubble baths, baby baths, vapor baths and shower gels.


PEG 6000 Distearate (peg-150 distearate) can also be used to thicken facial scrubs, facial cleansers, body scrubs and shaving foams, and finds application in color cosmetics as an auxiliary emulsifer (HLB ~18.4).
The typical use level of PEG 6000 Distearate (peg-150 distearate) is 2 – 4%.


PEG 6000 Distearate (peg-150 distearate) is in the form of solid, white to off-white waxy flakes and used as a thickener, emulsifier, solubilizer in cosmetics and personal care products.
Typical concentration of PEG 6000 Distearate (peg-150 distearate) is 0.5-50%.


PEG 6000 Distearate (peg-150 distearate) is an efficient thickening agent for shampoos, body washes or foam baths.
Even at low levels, PEG 6000 Distearate (peg-150 distearate) results in a high viscosity modifying effect.
PEG 6000 Distearate (peg-150 distearate) is used in formulations which are difficult to thicken.


PEG 6000 Distearate (peg-150 distearate) is used in formulations which are difficult to thicken.
Industry Primarily Used of PEG 6000 Distearate (peg-150 distearate): Cosmetics, Pharmaceuticals, Inks & Coatings
PEG 6000 Distearate (peg-150 distearate) is particularly effective for the thickening of clear, mild, amphoteric-containing surfactant systems, such as shampoos, body washes, bubble baths, baby baths, vapor baths, and shower gels.


PEG 6000 Distearate (peg-150 distearate) can also be used to thicken facial scrubs, facial cleansers, body scrubs, and shaving foams, and finds application in color cosmetics as an auxiliary emulsifier (HLB ~18.4).
The typical use level of PEG 6000 Distearate (peg-150 distearate) is 2 – 4%.


PEG 6000 Distearate (peg-150 distearate) is commonly used to thicken mild, amphoteric-containing surfactant systems, such as baby shampoos, baby bath and facial scrubs.
PEG 6000 Distearate (peg-150 distearate) is also used in deodorants, facial cleansers, facial color cosmetics, liquid hand soaps, shampoos, shaving products and shower gels/body washes.


PEG 6000 Distearate (peg-150 distearate) is commonly used to thicken mild, amphoteric-containing surfactant systems, such as baby shampoos, baby baths, facial scrubs, facial cleansers, body washes, body scrubs and shaving foams.


PEG 6000 Distearate (peg-150 distearate) also finds application in color cosmetics as an auxiliary emulsifer/
Due to its low toxicity PEG 6000 Distearate (peg-150 distearate) can be used as a lubricating coating for various surfaces in aqueous and non-aqueous environments, a reagent in biochemistry to create very high osmotic pressures, a polar stationary phase for gas chromatography and as a binder.



FUNCTION OF PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
PEG 6000 Distearate (peg-150 distearate) is commonly used to thicken mild, amphoteric-containing surfactant systems, such as baby shampoos, baby baths, facial scrubs, facial cleansers, body washes, body scrubs and shaving foams.
PEG 6000 Distearate (peg-150 distearate) also finds application in color cosmetics as an auxiliary emulsifer (HLB ~18.4).



FEATURES & BENEFITS OF PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
*Emulsifying Agent (O/W)
*Thickener (aqueous)



WHAT IS PEG 6000 DISTEARATE (PEG-150 DISTEARATE) USED FOR?
PEG 6000 Distearate (peg-150 distearate) is used mainly as a thickener in products like shampoos, conditioners, shower gels, face washes, hand washes, shaving creams, baby-care products etc.
*Skin care:
PEG 6000 Distearate (peg-150 distearate) is used as an emulsifier in creams and lotions
*Hair care:
PEG 6000 Distearate (peg-150 distearate) is used as an anti-static agent in conditioners



ORIGIN OF PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
PEG 6000 Distearate (peg-150 distearate) is produced by the esterification of stearic acid which is derived from palm kernel oil or other vegetable oils.



WHAT DOES PEG 6000 DISTEARATE (PEG-150 DISTEARATE) DO IN A FORMULATION?
*Emulsifying
*Viscosity controlling



SAFETY PROFILE OF PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
PEG 6000 Distearate (peg-150 distearate) is designated as safe to be used in products at a concentration of 5.0%.



FUNCTIONS OF PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
*Thickener,
*Viscosity Modifier,
*Viscosity Stabilizer



BENEFIT CLAIMS OF PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
*Rich Feel



BENEFITS AND USES OF PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
PEG 6000 Distearate (peg-150 distearate) is used to thicken products like shampoos, conditioners, shower gels, hand washes, shaving creams, etc.
PEG 6000 Distearate (peg-150 distearate) is an excellent emulsifier and is usually added to creams and lotions.
PEG 6000 Distearate (peg-150 distearate) mixes well with water and oil and enables them to clean dirt and grime from the surface.
PEG 6000 Distearate (peg-150 distearate) forms a film on the hair and reduces static and is therefore used in conditioners.
When added to paints and dyes, PEG 6000 Distearate (peg-150 distearate) thickens their consistency and emulsifies them.



HOW PEG 6000 DISTEARATE (PEG-150 DISTEARATE) WORKS?
PEG 6000 Distearate (peg-150 distearate) works by acting as a solubilizer for water-insoluble ingredients.
PEG 6000 Distearate (peg-150 distearate) reduces the surface tension of the substances and helps form emulsions.



CONCENTRATION AND SOLUBILITY OF PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
PEG 6000 Distearate (peg-150 distearate) is used at a concentration of 0.5% to 5% of the formulation.
PEG 6000 Distearate (peg-150 distearate) is soluble in water and ethanol and is insoluble in vegetable and mineral oil.



HOW TO USE PEG 6000 DISTEARATE (PEG-150 DISTEARATE)?
Heat PEG 6000 Distearate (peg-150 distearate) with other surfactants at 60oC and melt it completely.
Mix this blend into the water phase at 35oC and stir.
Add oil phase and adjust the pH.



FUNCTIONS OF PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
PEG 6000 Distearate (peg-150 distearate) is an ester made from the reaction of vegetable-derived triple-pressed grade stearic acid and a defined high molecular weight polyethylene glycol.
PEG 6000 Distearate (peg-150 distearate) is commonly used to thicken mild, amphoteric-containing surfactant systems, such as baby shampoos, baby baths, facial scrubs, facial cleansers, body washes, body scrubs and shaving foams.



STORAGE OF PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
Keep PEG 6000 Distearate (peg-150 distearate) container tightly closed.



BENEFITS / APPLICATION OF PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
PEG 6000 Distearate (peg-150 distearate) is a high molecular weight distearate of polyethyleneglycol that provides excellent properties of thickening to formulations based on surfactants agents.

PEG 6000 Distearate (peg-150 distearate) is a differentiated thickener with excellent suavity.
PEG 6000 Distearate (peg-150 distearate) can be used in many cosmetic formulations, such as shampoos for adults, for children, foam bath, liquid soaps, etc.

PEG 6000 Distearate (peg-150 distearate) is a versatile product that can be used as the unique
thickening agent or even associated to alkanolamides, etoxilated
fatty alcohols, and betaines.

Due to the ethylene oxide groups in its molecule, PEG 6000 Distearate (peg-150 distearate) acts improving the viscosity of surfactants usually used in soft formulations.
Therefore, surfactants such as sorbitan monolaurate, sulfosuccinates, and betaines have PEG 6000 Distearate (peg-150 distearate)'s thickener profile improved.

When associated to etoxilated fatty alcohols PEG 6000 Distearate (peg-150 distearate) shows a
special synergy that allows that alkanol amides be partially or totally
substituted.

PEG 6000 Distearate (peg-150 distearate) should be added under agitation to the water of formulation – total or part of the water – at 70-80°C.
In cold processing, PEG 6000 Distearate (peg-150 distearate) must be previously dissolved before
incorporate it to the formulation.

It is better elaborate an aqueous solution at 10% and heat this solution until 70-80°C or PEG 6000 Distearate (peg-150 distearate) can be solubilized in the amide associated to an amphoteric, heating to 65-75°C.
After this step, the cold processing can continue.



MAIN PROPERTIES OF PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
*Surfactant
*Viscosity Controller



INDICATIONS OF PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
PEG 6000 Distearate (peg-150 distearate) can be incorporated into shampoos, children's shampoos, liquid soaps and bubble baths.



PHYSICAL and CHEMICAL PROPERTIES of PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
Boiling Point: 492-497°C
Melting Point: 52-57°C
Hydroxyl Value: 5 max.
Solubility: Soluble in water and ethanol
Insoluble in mineral and vegetable oil
Saponification Value: 165-175 mgKOH/g
Appearance Form: solid
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point:
Melting point/range: 35 - 37 °C
Initial boiling point and boiling range: No data available
Flash point: > 113,00 °C - closed cup
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available

Vapor pressure: No data available
Vapor density: No data available
Density: No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Appearance: Flakes/Solid
Color: White to slight yellowish
Acid value: 0 – 9 mg KOH/g
Iodine value: 0 – 1 g I2/100 g

Saponification value: 14 – 25 mg KOH/g
Name: PEG 6000 DISTEARATE
CAS Registry Number: 9005-08-7
Cloud Point: 83C (1% AQ. SOLN.)
Comments: NONIONIC
Density (Specific Gravity)= (25C): 1.075
HLB Number: 18.4
Instrument Name:DIGILAB FTS-40
Melting Point: 55C
Sample Description: OFF-WHITE FLAKES
EINECS: N/A
CAS No.: 9005-08-7
Density: N/A
PSA: 77.76000
LogP: 4.91340
Solubility: N/A
Melting Point: 35-37 °C

Formula: (C2H4O)n.C36H70O3
Boiling Point: 495.3oC at 760 mmHg
Molecular Weight: 332.51900
Flash Point: >230 °F
Transport Information: N/A
Appearance: Solid
Safety: Risk Codes: N/A
Hazard Symbols: N/A
Color: 1 Gard Max
Acid Value: 9.0 Max
Saponification Value: 14 - 20
Hydroxyl Value: 2.5 Max
Appearence: Off-white solid
Moisture: 1.0% Max
pH: 4.0 - 7.0 (@ 3% Solution Distilled)



FIRST AID MEASURES of PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water.
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.



EXPOSURE CONTROLS/PERSONAL PROTECTION of PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Safety glasses.
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Recommended storage temperature see product label.



STABILITY and REACTIVITY of PEG 6000 DISTEARATE (PEG-150 DISTEARATE):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
no information available

PEG 7 Glyceryl Cocoate What Is PEG 7 Glyceryl Cocoate? PEG 7 Glyceryl Cocoate, PEG-30 Glyceryl Cocoate, PEG-40 Glyceryl Cocoate, PEG-78 Glyceryl Cocoate and PEG-80 Glyceryl Cocoate are polyethylene glycol ethers of Glyceryl Cocoate. In cosmetics and personal care products, PEG Glyceryl Cocoate ingredients are used in the formulation of hair dyes and colors, shampoos, cleaning products, and skin care and bath products. Why is PEG 7 Glyceryl Cocoate used in cosmetics and personal care products? PEG-7 Glyceryl Cocoate acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance. It also helps to form emulsions by reducing the surface tension of the substances to be emulsified. PEG-30, -40, -78 and -80 Glyceryl Cocoate clean the skin and hair by helping water to mix with oil and dirt so that these substances can be rinsed away. They also help other ingredients to dissolve in a solvent in which they would not normally dissolve. Scientific Facts: PEG 7 Glyceryl Cocoate ingredients are produced from coconut oil-derived fatty acids. The different chain length PEGs are formed using ethylene oxide and water, with the average number of moles of ethylene oxide used corresponding to the number in the name. PEG 7 Glyceryl Cocoate ingredients are produced from coconut oil-derived fatty acids. PEG 7 Glyceryl Cocoate functions as a skin conditioning agent, emollient, surfactant and an emulsifying agent. They are used in the formulation of hair dyes and colors, shampoos, skin care and bath products. PEG-7 GLYCERYL COCOATE is classified as : Emulsifying Surfactant COSING REF No:77274 Chem/IUPAC Name:Poly(oxy-1,2-ethanediyl), .alpha.,.alpha.',.alpha.''-1,2,3-propanetriyltris-.omega.-hydroxy-, monococonut acid ester (7 mol EO average molar ratio) Galaxy PEG 7 Glyceryl Cocoate is a water soluble polyol fatty acid ester. PEG 7 Glyceryl Cocoate is a non-ionic surface active agent and acts as an emulsifying agent. PEG-7 Glyceryl Cocoate has emollient and conditioning effects on skin. It also has super-fatting properties. What Is PEG-7 Glyceryl Cocoate? PEG 7 glyceryl cocoate is a synthetic polymer that functions as an emollient, surfactant, and emulsifier in cosmetics and skincare products. PEG 7 glyceryl cocoate is a polyethylene glycol (PEG) ether of glyceryl cocoate. Glyceryl cocoate is a monoester of glycerin and coconut fatty acids, which are both very beneficial to the skin. Glycerin, also referred to as glycerol, is a natural alcohol and humectant that helps the skin to retain moisture. Coconut fatty acids restore the skin’s lipid barrier, which also helps to improve the skin’s moisture retention. PEG 7 glyceryl cocoate is produced by the ethoxylation of glyceryl cocoate. Ethoxylation is a chemical reaction in which ethylene oxide is added to a substrate. In this case, 7 units of ethylene oxide are added to glyceryl cocoate (hence the 7 in the ingredient name). THE BREAKDOWN PEG-7 Glyceryl Cocoate THE GOOD:Helps to protect the skin’s natural barrier, improving moisture retention. It also helps to improve the texture and feel of the product. THE NOT SO GOOD:There are concerns about the presence of 1,4-dioxane in this ingredient. This is less of a concern more recently as the process of purifying PEG 7 glyceryl cocoate is highly regulated. WHO IS IT FOR?All skin types except those that have an identified allergy to it. SYNERGETIC INGREDIENTS:Works well with most ingredients KEEP AN EYE ON:Nothing to keep an eye on here. Why Is PEG 7 Glyceryl Cocoate Used? In cosmetics and skincare products, PEG 7 glyceryl cocoate functions as an emollient, surfactant, and emulsifier. PEG 7 glyceryl cocoate also helps to protect the skin’s natural barrier and retain the skin’s moisture levels. Emollient As an emollient, PEG 7 glyceryl cocoate provides a lightweight and non-greasy barrier that helps to increase moisture retention at the skin’s surface. This property makes PEG 7 glyceryl cocoate very useful for products such as lotions, creams, and facial moisturizers. While all skin types can benefit from emollients like PEG 7 glyceryl cocoate, emollients are especially helpful for those who have dry, rough, and/or flaky skin. Emollients may help to alleviate these symptoms, leaving the skin looking and feeling soft and smooth. In addition, emollients may benefit those that suffer from conditions such as eczema, psoriasis, or other inflammatory skin conditions. Surfactant PEG 7 glyceryl cocoate also functions as a surfactant because it contains one end that is hydrophilic or attracted to water and one end that is lipophilic or attracted to oil. Surfactants work by lowering the surface tension between two substances, such as two liquids or a liquid and a solid. This allows surfactants to attract and suspends oils, dirt, and other impurities that have accumulated on the skin and wash them away. Due to these properties, PEG 7 glyceryl cocoate can be found in many different cleansers, shampoos, and body washes. Emulsifier As an emulsifier, PEG 7 glyceryl cocoate is often used in formulations that contain both water and oil components. Mixing water and oil can be difficult as they tend to separate and split. To address this problem, an emulsifier like PEG 7 glyceryl cocoate can be added to improve the consistency of a product, which enables an even distribution of topical skin care benefits. Is PEG 7 Glyceryl Cocoate Safe? The safety of the PEG glyceryl cocoate ingredients, including PEG 7 glyceryl cocoate, has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel, a group responsible for evaluating the safety of skincare and cosmetic ingredients. The Expert Panel evaluated the scientific data and concluded that these ingredients were safe for use in rinse-off products and safe up to 10% in leave-on products. Despite the approval of PEG 7 glyceryl cocoate by the CIR Expert Panel, there are concerns about the presence of ethylene oxide in this ingredient. This is because the process of ethoxylation may lead to contamination with 1,4-dioxane, a potentially dangerous by-product. 1,4-dioxane is a known animal carcinogen that penetrates readily into the skin. According to the National Toxicology Program, ‘1,4-dioxane is reasonably anticipated to be a human carcinogen.’ It has also been linked with skin allergies. However, the potential presence of 1,4-dioxane can be controlled through purification steps to remove it before blending PEG-7 glyceryl cocoate into cosmetic formulations. what is PEG 7 Glyceryl Cocoate: PEG 7 Glyceryl Cocoate is a non-ionic ethoxylated surfactant with over-greasing and solubilizing properties. PEG 7 Glyceryl Cocoate is a hydrophilic oil with a light yellow color and a characteristic odor. Chemically PEG 7 Glyceryl Cocoate consists of polyethylene glycol and coconut fatty acids. In cosmetics PEG 7 Glyceryl Cocoate is used as a degreaser in shampoos and body cleansers, thanks to its lubricating, emollient and conditioned properties for the skin and hair. Furthermore PEG 7 Glyceryl Cocoate improves the foam quality of the detergents in which it is inserted. PEG 7 Glyceryl Cocoate is also used for its solubilizing properties against fat-soluble substances in aqueous systems, such as some active ingredients (menthol, camphor, salicylic acid) and essential oils and having an HLB of about 11 can also be used as a coemulsifier. PEG 7 Glyceryl Cocoate can be inserted into any type of cleansing product, for skin and hair. PEG 7 Glyceryl Cocoate is often used used as a solubilizer and emollient in hair sprays without rinsing and in micellar cleansing waters. Recommended use percentage: from 1 to 10%. PEG 7 Glyceryl Cocoate is soluble in water and aqueous solutions of tensiottivi is stable in a pH range between 5 and 8. Non-ionic, ethoxlyated polyethylene glycol ester made from glycerin & coconut oil. Clear oily liquid, characteristic odor. Soluble in water & alcohols, insoluble in oils. HLB value 11 (gives oil-in-water emulsions). PEG compounds are harmless but contentious ingredients, as the manufacturing process can involve contaminants. We choose to work with suppliers who ensure that all of our PEG compounds are completely safe for cosmetic use. PEG 7 Glyceryl cocoate is a solubilizer, used to blend all formula ingredients together into a stable and uniformly dispersed product. As part of our mission to provide the greenest formulas possible, we are working hard to remove this ingredient from our portfolio. A clear, light yellow water-loving oil that comes from coconut/palm kernel oil and glycerin. PEG 7 Glyceryl Cocoate's a mild cleansing agent popular in baby washes and sensitive skin formulas. PEG 7 Glyceryl Cocoate's also a so-called solubilizer that helps to dissolve oils and oil-soluble ingredients (e.g.essential oils or salicylic acid) in water-based formulas. INCI: PEG-7 Glyceryl Cocoate PEG 7 Glyceryl Cocoate is a multifunctional substance which is an ideal emulsifying agent, emollient and solvent material. PEG 7 Glyceryl Cocoate is of natural origin, obtained from coconut oil and glycerin. Emulsifiers: HLB 10. The product is used in recipes: A facial cleansing micellar fluid A facial cleansing gel for sensitive skin eco A body wash emulsion with a chamomile extract A nourishing and moisturizing body wash gel with silk and red poppy extracts. A hydrophilic cleansing oil for mixed skin: almond, safflower A hydrophilic cleansing oil for dry skin: avocado, borage A hydrophilic cleansing oil for mature skin: karite, argan A hydrophilic cleansing oil for acne and oily skin: sunflower, safflower A nourishing and moisturizing body wash gel with silk and red poppy extracts. A moisturizing shampoo with silk. A nourising and relaxing shampoo with red poppy flower extract. A regenerating shampoo for damaged hair with keratin. A shampoo for dyed hair with an argan oil. A shampoo for oily skin/hair with a common bahu extract. peg 7 GLYCERYL COCOATE is classified as : Emollient Emulsifying CAS Number 61789-05-7 EINECS/ELINCS No: 263-027-9 COSING REF No: 34052 Chem/IUPAC Name: Glycerides, coco mono- This synthetic polymer is based on PEG (polyethylene glycol) and fatty acids derived from coconut oil. Due to the presence of PEG, this ingredient may contain potentially toxic manufacturing impurities such as 1,4-dioxane. Function(s): Skin-Conditioning Agent - Emollient; Surfactant - Emulsifying Agent PEG 7 Glyceryl Cocoate acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance. PEG 7 Glyceryl Cocoate also helps to form emulsions by reducing the surface tension of the substances to be emulsified. Description of PEG 7 Glyceryl Cocoate: Non-ionic, ethoxlyated polyethylene glycol ester made from glycerin & coconut oil. Clear oily liquid, characteristic odor. Soluble in water & alcohols, insoluble in oils. HLB value 11 (gives oil-in-water emulsions). CAS: 68201-46-7 INCI Name: PEG-7 glyceryl monococoate Benefits of PEG 7 Glyceryl Cocoate: Multifunctional agent with excellent emulsifying, emollient, refatting & thickening properties Very useful as surfactant and foam booster Has good conditioning effect for soft and smooth skin Use of PEG 7 Glyceryl Cocoate: Can be added to formulas as is, usual concentration 1 - 10%. For external use only. Applications of PEG 7 Glyceryl Cocoate: Universally applicable, especially in liquid soaps, lotions, body washes, shower gels, hair shampoos, facial cleansers, bubble baths, decorative cosmetics. Country of Origin of PEG 7 Glyceryl Cocoate: Germany Raw material source of PEG 7 Glyceryl Cocoate: Coconut oil and polyethylene glycol Manufacture of PEG 7 Glyceryl Cocoate: PEG glyceryl cocoate is manufactured by the ethoxylation (polymerization of ethylene oxide) of glyceryl cocoate. Animal Testing: Not animal tested GMO: GMO free (does not contain plant-derived components) Vegan: Does not contain animal-derived components Propylene Glycol / Peg 7 Glyceryl Cocoate is used for Hemolysis, Central nervous system depression, Hyperosmolality, Lactic acidosis, Skin conditioning and other conditions. Uses of PEG 7 Glyceryl Cocoate Propylene Glycol / Peg 7 Glyceryl Cocoate is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms: Hemolysis Central nervous system depression Hyperosmolality Lactic acidosis Skin conditioning Propylene Glycol / Peg 7 Glyceryl Cocoate may also be used for purposes not listed here. Side-effects of PEG 7 Glyceryl Cocoate The following is a list of possible side-effects that may occur in medicines that contain Propylene Glycol / Peg 7 Glyceryl Cocoate. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away. Hypersensitivity Local irritation Diaphoresis Unresponsiveness Propylene Glycol / Peg 7 Glyceryl Cocoate may also cause side-effects not listed here. Precautions of PEG 7 Glyceryl Cocoate Before using Propylene Glycol / Peg 7 Glyceryl Cocoate, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below. Allergy Pregnancy or lactation Sensitive to any topical lotions or creams Skin disorders Skin infections When not to use Propylene Glycol / Peg 7 Glyceryl Cocoate Hypersensitivity to Propylene Glycol / Peg 7 Glyceryl Cocoate is a contraindication. In addition, Propylene Glycol / Peg 7 Glyceryl Cocoate should not be used if you have the following conditions: Hypersensitivity Frequently asked Questions about of PEG 7 Glyceryl Cocoate Is Propylene Glycol / Peg 7 Glyceryl Cocoatesafe to use when pregnant? Propylene Glycol: Please consult with your doctor for case-specific recommendations. Peg 7 Glyceryl Cocoate: Please consult with your doctor for case-specific recommendations. Is Propylene Glycol / Peg 7 Glyceryl Cocoatesafe while breastfeeding? Propylene Glycol: Please discuss the risks and benefits with your doctor. Peg 7 Glyceryl Cocoate: Please discuss the risks and benefits with your doctor. Is it safe to drive or operate heavy machinery when using this product? If you experience drowsiness, dizziness, hypotension or a headache as side-effects when usingPropylene Glycol / Peg 7 Glyceryl Cocoatemedicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Propylene Glycol / Peg 7 Glyceryl Cocoate. Always consult with your doctor for recommendations specific to your body and health conditions. Is PEG 7 Glyceryl Cocoate or product addictive or habit forming? Most medicines don't come with a potential for addiction or abuse. Usually, the government's categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body's dependence to medicines without the advice of a doctor. Can I stop using PEG-7 Glyceryl Cocoate immediately or do I have to slowly wean off the use? Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using. Overdosage of Propylene Glycol / Peg 7 Glyceryl Cocoate Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Propylene Glycol / Peg 7 Glyceryl Cocoate, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information. Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage. Please consult your physician or pharmacist or product package for more information. Storage of Propylene Glycol / Peg 7 Glyceryl Cocoate Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets. Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Propylene Glycol / Peg 7 Glyceryl Cocoate. Expired Propylene Glycol / Peg-7 Glyceryl Cocoate Taking a single dose of expired Propylene Glycol / Peg 7 Glyceryl Cocoate is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drugs. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications. Peg 7 Glyceryl Cocoate is the basis of a number of laxatives. Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy. Peg 7 Glyceryl Cocoate is also used as an excipient in many pharmaceutical products. When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood. The possibility that Peg 7 Glyceryl Cocoate could be used to fuse axons is being explored by researchers studying peripheral nerve and spinal cord injury. Chemical uses of Polyethylene glycol (Peg-7 Glyceryl Cocoate) The remains of the 16th century carrack Mary Rose undergoing conservation treatment with Peg 7 Glyceryl Cocoate in the 1980s. Terra cotta warrior, showing traces of original color Because Peg 7 Glyceryl Cocoate is a hydrophilic molecule, it has been used to passivate microscope glass slides for avoiding non-specific sticking of proteins in single-molecule fluorescence studies. Polyethylene glycol has a low toxicity and is used in a variety of products. The polymer is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments. Since Peg 7 Glyceryl Cocoate is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures (on the order of tens of atmospheres). It also is unlikely to have specific interactions with biological chemicals. These properties make Peg 7 Glyceryl Cocoate one of the most useful molecules for applying osmotic pressure in biochemistry and biomembranes experiments, in particular when using the osmotic stress technique. Polyethylene glycol is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers. Peg 7 Glyceryl Cocoate has also been used to preserve objects that have been salvaged from underwater, as was the case with the warship Vasa in Stockholm, and similar cases. It replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries. In addition, Peg 7 Glyceryl Cocoate is used when working with green wood as a stabilizer, and to prevent shrinkage. Peg 7 Glyceryl Cocoate has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China. These painted artifacts were created during the Qin Shi Huang (first emperor of China) era. Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xi'an air. The paint would subsequently flake off in about four minutes. The German Bavarian State Conservation Office developed a Peg 7 Glyceryl Cocoate preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers. Peg 7 Glyceryl Cocoate is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning. Peg 7 Glyceryl Cocoate derivatives, such as narrow range ethoxylates, are used as surfactants. Peg 7 Glyceryl Cocoate has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes. Peg 7 Glyceryl Cocoate has also been used as a propellent on the UGM-133M Trident II Missile, in service with the United States Air Force. Biological uses of PEG-7 Glyceryl Cocoate Peg 7 Glyceryl Cocoate is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions. Peg 7 Glyceryl Cocoate is commonly used as a precipitant for plasmid DNA isolation and protein crystallization. X-ray diffraction of protein crystals can reveal the atomic structure of the proteins. Peg 7 Glyceryl Cocoate is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas. Polymer segments derived from Peg 7 Glyceryl Cocoate polyols impart flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam cushions. In microbiology, Peg 7 Glyceryl Cocoate precipitation is used to concentrate viruses. Peg 7 Glyceryl Cocoate is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro. Gene therapy vectors (such as viruses) can be Peg 7 Glyceryl Cocoate-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect. The size of the Peg 7 Glyceryl Cocoate polymer has been shown to be important, with larger polymers achieving the best immune protection. Peg 7 Glyceryl Cocoate is a component of stable nucleic acid lipid particles (SNALPs) used to package siRNA for use in vivo. In blood banking, Peg 7 Glyceryl Cocoate is used as a potentiator to enhance detection of antigens and antibodies. When working with phenol in a laboratory situation, Peg 7 Glyceryl Cocoate 300 can be used on phenol skin burns to deactivate any residual phenol (some references are required). In biophysics, polyethylene glycols are the molecules of choice for the functioning ion channels diameter studies, because in aqueous solutions they have a spherical shape and can block ion channel conductance. Commercial uses of PEG-7 Glyceryl Cocoate Peg 7 Glyceryl Cocoate is the basis of many skin creams (as cetomacrogol) and personal lubricants (frequently combined with glycerin). Peg 7 Glyceryl Cocoate is used in a number of toothpastes as a dispersant. In this application, it binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste. Peg 7 Glyceryl Cocoate is also under investigation for use in body armor, and in tattoos to monitor diabetes. In low-molecular-weight formulations (e.g. Peg 7 Glyceryl Cocoate 400), it is used in Hewlett-Packard designjet printers as an ink solvent and lubricant for the print heads. Peg 7 Glyceryl Cocoate is also used as an anti-foaming agent in food and drinks – its INS number is 1521 or E1521 in the EU. Industrial uses of PEG-7 Glyceryl Cocoate A nitrate ester-plasticized polyethylene glycol (NEPE-75) is used in Trident II submarine-launched ballistic missile solid rocket fuel. Dimethyl ethers of Peg 7 Glyceryl Cocoate are the key ingredient of Selexol, a solvent used by coal-burning, integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the gas waste stream. Peg 7 Glyceryl Cocoate has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator. Peg 7 Glyceryl Cocoate is also used as a polymer host for solid polymer electrolytes. Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving Peg 7 Glyceryl Cocoate, with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future. Peg 7 Glyceryl Cocoate is injected into industrial processes to reduce foaming in separation equipment. Peg 7 Glyceryl Cocoate is used as a binder in the preparation of technical ceramics. Recreational uses Peg 7 Glyceryl Cocoate is used to extend the size and durability of very large soap bubbles. Peg 7 Glyceryl Cocoate is the main ingredient in many personal lubricants. Health effects of PEG-7 Glyceryl Cocoate Peg 7 Glyceryl Cocoate is considered biologically inert and safe by the FDA. However, a growing body of evidence shows the existence of anti Peg 7 Glyceryl Cocoate antibodies in approximately 72% of the population based on plasma samples from 1990–1999. The FDA has been asked to investigate the possible effects of Peg 7 Glyceryl Cocoate in laxatives for children. Due to its ubiquity in a multitude of products and the large percentage of the population with antibodies to Peg 7 Glyceryl Cocoate, hypersensitive reactions to Peg 7 Glyceryl Cocoate are an increasing concern. Allergy to Peg 7 Glyceryl Cocoate is usually discovered after a person has been diagnosed with an allergy to an increasing number of seemingly unrelated products, including processed foods, cosmetics, drugs, and other substances that contain Peg 7 Glyceryl Cocoate or were manufactured with Peg 7 Glyceryl Cocoate. When Peg 7 Glyceryl Cocoate is chemically attached to therapeutic molecules (such as protein drugs or nanoparticles), it can sometimes be antigenic, stimulating an anti-Peg 7 Glyceryl Cocoate antibody response in some patients. This effect has only been shown for a few of the many available Peg 7 Glyceryl Cocoate therapeutics, but it has significant effects on clinical outcomes of affected patients. Other than these few instances where patients have anti-Peg 7 Glyceryl Cocoate immune responses, it is generally considered to be a safe component of drug formulations.

PEG 7 Glyceryl Cocoate is a non-ionic surfactant derived from coconut fatty acids and ethylene oxide.
PEG-7 Glyceryl cocoate is the polyethylene glycol ether of glyceryl cocoate.
Glyceryl cocoate is formed from glycerin and fatty acid obtained from coconut oil.
PEG 7 Glyceryl Cocoate is produced by ethoxylation of glyceryl cocoate, with 7 ethylene oxide monomer units in the polymer chain.


CAS Number: 66105-29-1, 68201-46-7
Chem/IUPAC Name: Poly(oxy-1,2-ethanediyl), .alpha.,.alpha.',.alpha.''-1,2,3-propanetriyltris-.omega.-hydroxy-, monococonut acid ester (7 mol EO average molar ratio)


PEG 7 Glyceryl Cocoate is the polyethylene glycol ether of glyceryl cocoate.
Glyceryl cocoate is formed from glycerin and fatty acid obtained from coconut oil.
PEG 7 Glyceryl Cocoate is produced by ethoxylation of glyceryl cocoate, with 7 ethylene oxide monomer units in the polymer chain.


PEG 7 Glyceryl Cocoate is non-ionic, ethoxlyated polyethylene glycol ester made from glycerin & coconut oil
PEG 7 Glyceryl Cocoate is not a finished cosmetic product.
This synthetic polymer, PEG 7 Glyceryl Cocoate, is based on PEG (polyethylene glycol) and fatty acids derived from coconut oil.


Due to the presence of PEG, PEG 7 Glyceryl Cocoate may contain potentially toxic manufacturing impurities such as 1,4-dioxane.
PEG 7 Glyceryl Cocoate is a liquid raw material with a density of 0.940 GR / CM3 , in liquid form, with a slightly yellow color and a characteristic odor.
PEG 7 Glyceryl Cocoate is a complex blend of a polyethylene glycol (PEG) derivative and coconut + glycerin-derived cleansing agent, meaning that it can be described as coconut-derived.


The blend can be an emollient, emulsifier, and surfactant.
As an emollient, PEG 7 Glyceryl Cocoate helps soften and smooth skin, making it a useful addition to moisturisers, hair conditioners, and cleansers.
The Cosmetic Ingredient Review panel has ruled that PEG 7 Glyceryl Cocoate is safe as used in rinse-off products and is safe in leave-on products in amounts up to 10%.


PEG 7 Glyceryl Cocoate can be added to formulas as is. Typical use level of PEG 7 Glyceryl Cocoate is 1 - 10%.
PEG 7 Glyceryl Cocoate is a non-ionic surfactant, used mainly in cosmetic applications.
PEG 7 Glyceryl Cocoate is a derivative based on renewable vegetable raw materials such as polyoxyethylated fatty acid esters and glycerol.


The content of the active substance exceeds 99%.
PEG 7 Glyceryl Cocoate is non-ionic, ethoxlyated polyethylene glycol ester made from glycerin & coconut oil.
PEG 7 Glyceryl Cocoate's HLB value 11 (gives oil-in-water emulsions).


PEG 7 Glyceryl Cocoate is used for external use only.
PEG 7 Glyceryl Cocoate is used universally applicable, especially in liquid soaps, lotions, body washes, shower gels, hair shampoos, facial cleansers, bubble baths, decorative cosmetics.


PEG-7 Glyceryl Cocoate is a synthetic polymer that is made by the reaction of polyethylene glycol (PEG) and the fatty acids derived from coconut or palm kernel oil.
PEG 7 Glyceryl Cocoate is a mild compound that helps to combine oil-based and water-based ingredients together.
PEG 7 Glyceryl Cocoate is a water soluble polyol fatty acid ester.


PEG 7 Glyceryl Cocoate is a non-ionic surface active agent and acts as an emulsifying agent.
PEG 7 Glyceryl Cocoate has emollient and conditioning effects on skin.
PEG 7 Glyceryl Cocoate also has super-fatting properties.
PEG is a large family of polymer compounds whose applications and properties differ according to their molecular weight and structure.



USES and APPLICATIONS of PEG 7 GLYCERYL COCOATE:
PEG 7 Glyceryl Cocoate, in addition to providing the benefits of the individual molecules, i.e. PEG, glycerol and coconut oil, a combination of all of them, also makes it an emollient, surfactant and emulsifier in products cosmetics.
Glycerol and PEG have the property of attracting water molecules and making them available to the skin.


Thus, PEG 7 Glyceryl Cocoate helps dry skin improve considerably by acting as an emollient.
When used in any product and applied to the skin, PEG 7 Glyceryl Cocoate forms a semi-permeable film on the skin surface that not only protects the skin from external factors, but also preserves moisture.


PEG 7 Glyceryl Cocoate is also beneficial for skin affected by eczema, psoriasis, and other inflammatory conditions.
As previously mentioned, when PEG 7 Glyceryl Cocoate functions as an emulsifier, it stabilizes the product and prevents the components from separating into their oil and water components, and rather provides a consistent and homogeneous mix of ingredients in the product.


As a surfactant, PEG 7 Glyceryl Cocoate helps remove dirt trapped in oil from the skin by helping it mix with water, which can be easily rinsed away.
In this way, PEG 7 Glyceryl Cocoate provides the skin with a fresh and rejuvenated appearance.
PEG 7 Glyceryl Cocoate is used in formulations of liquid soaps, body washes, facial cleansers, shampoos, and other personal care products.


PEG 7 Glyceryl Cocoate is used as raw material for making cosmetics or add directly to finished skin care products.
Use of PEG 7 Glyceryl Cocoate: Can be added to formulas as is, usual concentration 1 - 10%.
PEG 7 Glyceryl Cocoate is used for external use only.


Applications of PEG 7 Glyceryl Cocoate: Universally applicable, especially in liquid soaps, lotions, body washes, shower gels, hair shampoos, facial cleansers, bubble baths, decorative cosmetics.
PEG 7 Glyceryl Cocoate is used appling a product in cosmetics and personal hygiene.


PEG-7 Glyceryl Cocoate acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance.
PEG 7 Glyceryl Cocoate also helps to form emulsions by reducing the surface tension of the substances to be emulsified.
PEG 7 Glyceryl Cocoate is Regenerative in shampoo, shower gel, liquid soaps.


PEG 7 Glyceryl Cocoate is an ester obtained from emollient glycerol ethoxylated.
PEG 7 Glyceryl Cocoate is a clear, light yellow hydrophilic emollient for shampoo, shower gels and bath foam formulations and a solubility enhancer for essential oils and fragrances and a co-emulsifier for O/W emulsions, creams and lotions.


PEG 7 Glyceryl Cocoate is a solubilizer for lipophilic substances.
PEG 7 Glyceryl Cocoate is a hydrophilic refatting agent for mild shampoos, shower and bath preparations.
PEG 7 Glyceryl Cocoate has leaves a pleasant skin feel.


PEG 7 Glyceryl Cocoate gives a dense, creamy foam.
PEG 7 Glyceryl Cocoate decreases irritation potential of surfactants.
PEG 7 Glyceryl Cocoate is clearly soluble in aqueous surfactant solutions.


PEG 7 Glyceryl Cocoate acts as a superfatting agent to hair and skin.
PEG 7 Glyceryl Cocoate is solubilize oils and oil-soluble ingredients (e.g. menthol, salicylic acid and its derivatives, camphor).
PEG 7 Glyceryl Cocoate is stable in medium pH range (app. 5 to 8).


PEG 7 Glyceryl Cocoate results in surfactant preparations with good foam quality.
PEG 7 Glyceryl Cocoate is used in the formulation of hair dyes and colors, shampoos, cleaning products, and skin care and bath products.
PEG 7 Glyceryl Cocoate is a non-ionic surfactant, derived from Glycerine and Coconut Oil.


PEG 7 Glyceryl Cocoate has emollient properties and is used as a re-fatting agent to balance the effect of aggressive primary surfactants.
PEG 7 Glyceryl Cocoate leaves the skin soft and the hair smooth and shiny.
PEG 7 Glyceryl Cocoate is stable at a wide range of pH and it is noted for giving substance and richness to foam.


In alcohol based lotions such as tonics or pre/after-shaving lotions, PEG 7 Glyceryl Cocoate has a lubricating effect and reduces stress on the skin.
PEG 7 Glyceryl Cocoate solubilises fats into water-based solutions.
PEG 7 Glyceryl Cocoate is used shower gels, bubble baths, mild detergents, liquid soaps, shampoos, 2 in 1 shampoos, hair dyes.


One advantage of PEG-7 Glyceryl Cocoate is that it is a very gentle surfactant, making it suitable for fine or delicate hair.
PEG 7 Glyceryl Cocoate is known for its moisturizing and softening properties, which help to keep hair soft and hydrated.
PEG 7 Glyceryl Cocoate is often used as an emulsifier and solubilizing agent in hair care products such as shampoos, conditioners, and lotions.


Additionally, PEG-7 Glyceryl Cocoate is water-soluble, making it easily miscible with other ingredients in hair care formulations.
This solubility also makes the surfactant easy to remove from hair during washing, preventing excessive buildup.
However, as with all ingredients, it is important to pay attention to the concentration of PEG-7 Glyceryl Cocoate in hair care products.


Too high concentrations can potentially cause skin and scalp irritations, so PEG 7 Glyceryl Cocoate is important to follow the manufacturer’s usage recommendations and watch for any adverse reactions.
In summary, PEG 7 Glyceryl Cocoate is a versatile and gentle ingredient often used in hair care products.


However, as with all ingredients, PEG 7 Glyceryl Cocoate is important to be mindful of its concentration in products and possible side effects.
With the proper formulation and appropriate use, PEG 7 Glyceryl Cocoate can help to maintain healthy, soft, and hydrated hair.
PEG 7 Glyceryl Cocoate is widely used in the cosmetic and industrial sector.


PEG 7 Glyceryl Cocoate's lubricating feature comes to the fore in its use.
PEG 7 Glyceryl Cocoate is generally used in hair care products, skin care products and color cosmetics.
PEG 7 Glyceryl Cocoate is an emulsifier that helps stabilise and thicken formulas, allowing to create solid products and therefore remove the need for unnecessary packaging and synthetic preservatives.


PEG 7 Glyceryl Cocoate also conditions the hair and skin, giving shine and softness.
As an emulsifier, PEG 7 Glyceryl Cocoate attracts and hold together water and oil-based ingredients such as rose infusion or jojoba oil.
Without emulsifiers, the formula would separate, causing oil droplets to float on top of the water.


PEG 7 Glyceryl Cocoate is a clear, light yellow water-loving oil that comes from coconut/palm kernel oil and glycerin.
PEG 7 Glyceryl Cocoate's a mild cleansing agent popular in baby washes and sensitive skin formulas.
PEG 7 Glyceryl Cocoate's also a so-called solubilizer that helps to dissolve oils and oil-soluble ingredients (e.g.essential oils or salicylic acid) in water-based formulas.


PEG 7 Glyceryl Cocoate, a compound belonging to this group, is an emulsifier that helps stabilize and thicken cosmetic formulations, thereby eliminating synthetic preservatives to form solid products.
As an ingredient in cosmetics, PEG 7 Glyceryl Cocoate enhances hair and skin care, leaving hair shiny and skin soft.


PEG 7 Glyceryl Cocoate is primarily used in products that do not have long-term contact with the skin, but are rinsed from the surface after a short time.
It is not recommended to apply products containing PEG-7 Glyceryl Cocoate to damaged skin.
PEG-7 Glyceryl Cocoate is a water-soluble ingredient that has many benefits in the cosmetic industry.


PEG 7 Glyceryl Cocoate conditions the skin and hair while also thickening the formulations.
PEG 7 Glyceryl Cocoate is basically an oil that is light yellow in color and has a distinctive odor.
Categorizing broadly, PEG 7 Glyceryl Cocoate is an emulsifier, emollient, and surfactant.
PEG-7 Glyceryl Cocoate can be found in products like cleansers, moisturizers, hair conditioners, etc.


-Acts as a lubricant:
On the surface of your skin, it acts as a lubricant to give it a soft, smooth feel.
PEG 7 Glyceryl Cocoate's also used in formulas to help create an emulsion.
An ether of Glyceryl Cocoate, PEG 7 Glyceryl Cocoate's used in personal care products like hair dyes, shampoos, conditioners, and skincare and bath products.


-Application of PEG 7 Glyceryl Cocoate:
*liquid soaps,
*body lotions,
*shower gels,
*after shave and other alcohol preparations,
*intimate hygiene lotions and gels,
*shampoo,
*face cleansers (face gels and foams, washing oils, tonics, micellar liquids),


-Application of PEG 7 Glyceryl Cocoate:
*bath lotions,
*creams and balms
*sunscreens,
*colouring cosmetics,
*hair styling preparations,
*protective lipstick preparations,
*dishwashing liquids,
*car chemicals.



WHAT IS PEG 7 GLYCERYL COCOATE USED FOR?
PEG-7 Glyceryl Cocoate is a multi-functional ingredient that can be found in a range of products such as cleansers, hair conditioners, and shampoos.
PEG 7 Glyceryl Cocoate has benefits for both skin and hair.

*Hair care:
PEG 7 Glyceryl Cocoate effortlessly combines oil and water together - thus proving beneficial in cleaning the dirt and oil out of the hair.
PEG 7 Glyceryl Cocoate treats rough and dry hair to leave them feeling healthy

*Skin care:
PEG 7 Glyceryl Cocoate helps in restoring the skin’s natural barrier and locks in moisture to give smoothness and lawlessness.
PEG 7 Glyceryl Cocoate is lightweight and non-greasy, so it does not weigh the skin down

*Cosmetic products:
PEG 7 Glyceryl Cocoate improves the look and feel of cosmetic products by adding desired thickness and texture to them.
PEG 7 Glyceryl Cocoate mixes oil and water components together and thus stabilizes the formulations



GENERAL FEATURES OF PEG 7 GLYCERYL COCOATE:
PEG 7 Glyceryl Cocoate is the INCI name for compounds that are derivatives of glycerides and coconut oil.
PEG-7 Glyceryl Cocoate CAS number is 68201-46-7. The traditional name used in the literature is coconut oil monoglyceride polyoxyethylated with 7 moles of ethylene oxide.
PEG 7 Glyceryl Cocoate is obtained from polyethylene glycol, glycerol and fatty acid from coconut oil.
PEG-7 Glyceryl Cocoate has hydrophilic properties.
PEG 7 Glyceryl Cocoate is a non-ionic surfactant (emulsifies) with poor water solubility.
PEG 7 Glyceryl Cocoate comes as an oily liquid at room temperature.
PEG 7 Glyceryl Cocoate dissolves very well in non-polar solvents such as ethanol, isopropanol or acetone.
PEG-7 Glyceryl Cocoate has a characteristic odor and color ranging from straw yellow to light yellow.
The molar mass of PEG-7 Glyceryl Cocoate is approx. 600 g/mol.
PEG 7 Glyceryl Cocoate shows very good stability in the pH range of 5 to 8.



BENEFITS OF PEG 7 GLYCERYL COCOATE:
*Multifunctional agent with excellent emulsifying, emollient, refatting & thickening properties
*Very useful as surfactant and foam booster
*Has good conditioning effect for soft and smooth skin



FUNCTIONS OF PEG 7 GLYCERYL COCOATE:
*Skin-Conditioning Agent
*Emollient; Surfactant
*Emulsifying Agent



USES AND BENEFITS OF PEG 7 GLYCERYL COCOATE:
PEG 7 Glyceryl Cocoate, in addition to providing the benefits of the individual molecules, i.e. PEG, glycerol and coconut oil, a combination of all of them, also makes it an emollient, surfactant and emulsifier in products cosmetics.
Glycerol and PEG have the property of attracting water molecules and making them available to the skin.

Thus, PEG 7 Glyceryl Cocoate helps dry skin improve considerably by acting as an emollient.
When used in any product and applied to the skin, PEG 7 Glyceryl Cocoate forms a semi-permeable film on the skin surface that not only protects the skin from external factors, but also preserves moisture.

PEG 7 Glyceryl Cocoate is also beneficial for skin affected by eczema, psoriasis, and other inflammatory conditions.
As previously mentioned, when PEG 7 Glyceryl Cocoate functions as an emulsifier, it stabilizes the product and prevents the components from separating into their oil and water components, and rather provides a consistent and homogeneous mix of ingredients in the product.

As a surfactant, PEG 7 Glyceryl Cocoate helps remove dirt trapped in oil from the skin by helping it mix with water, which can be easily rinsed away.
In this way, PEG 7 Glyceryl Cocoate provides the skin with a fresh and rejuvenated appearance.
PEG 7 Glyceryl Cocoate is used in formulations of liquid soaps, body washes, facial cleansers, shampoos, and other personal care products as it helps it mix with water, which can be easily rinsed out.

In this way, PEG 7 Glyceryl Cocoate provides the skin with a fresh and rejuvenated appearance.
PEG 7 Glyceryl Cocoate is used in formulations of liquid soaps, body washes, facial cleansers, shampoos, and other personal care products.



FUNCTIONS OF PEG 7 GLYCERYL COCOATE IN COSMETIC PRODUCTS:
*SURFACTANT - CLEANSING:
PEG 7 Glyceryl Cocoate is used surface-active agent to clean skin, hair and / or teeth
*SURFACTANT - EMULSIFYING:
PEG 7 Glyceryl Cocoate allows the formation of finely dispersed mixtures of oil and water (emulsions)



COSMETIC USE OF PEG 7 GLYCERYL COCOATE:
*Effect of PEG-7 Glyceryl Cocoate in cosmetic formulations:
good cleansing properties, PEG 7 Glyceryl Cocoate is used in scalp and hair cleansing products such as shampoos or bubble baths;
If added to detergents, PEG 7 Glyceryl Cocoate improves the quality of the foam. Foam formation directly determines the mechanism that removes dirt and foreign matter from the surface;

PEG 7 Glyceryl Cocoate is a co-emulsifier for many substances that do not dissolve well in water, such as menthol, salicylic acid or essential oils.
PEG 7 Glyceryl Cocoate helps to form an emulsion and keep it stable.
Without emulsifiers, the formula would stratify and oil droplets would float on the water;

PEG 7 Glyceryl Cocoate is used as an emollient in hair care products.
Products containing PEG-7 Glyceryl Cocoate significantly improve the condition of dry skin;
When applied to the skin with creams, PEG 7 Glyceryl Cocoate forms a semi-permeable film on the surface, both protecting the skin against external factors and trapping moisture.

Emollients such as PEG-7 Glyceryl Cocoate are particularly beneficial for people with dry, rough skin and/or flaky skin.
Application of emollients helps alleviate these symptoms;
in cosmetics, PEG-7 Glyceryl Cocoate also acts as an emulsifier, where it stabilizes the product and helps oil and water-based ingredients emulsify, making the mixture sticky and homogeneous;

As a surfactant, PEG 7 Glyceryl Cocoate helps to remove the dirt accumulated in the oil on the skin, increases the mixing of the easily rinsed dirt with water.
Thus leaving the skin refreshed and rejuvenated;
functions include relubrication.
Washing removes oil/oil substances, so we use lubricants that restore the lipid barrier.



NON-COSMETIC USE OF PEG 7 GLYCERYL COCOATE:
PEG-7 Glyceryl Cocoate is particularly popular in the beauty industry.
PEG 7 Glyceryl Cocoate's properties characteristic of most surfactants is also used in the detergent industry, especially for household use.
For this reason, you can find, for example, PEG-7 Glyceryl Cocoate among the components of washing liquids.
PEG-7 Glyceryl Cocoate meets the same features and functions in automotive chemicals.



WHAT DOES PEG 7 GLYCERYL COCOATE DO IN A FORMULATION?
*Emollient
*Emulsifying
*Surfactant



PEG 7 GLYCERYL COCOATE AT A GLANCE:
*Emollient, surfactant, and emulsifier that’s partially derived from coconut
*Often used in moisturisers, hair conditioners, and cleansers
*Purification process helps control any potentially dangerous byproducts
*Deemed safe as used in cosmetics



BENEFITS OF PEG 7 GLYCERYL COCOATE:
*Multifunctional agent with excellent emulsifying, emollient, refatting & thickening properties
*Very useful as surfactant and foam booster
*Has good conditioning effect for soft and smooth skin



ADVANTAGES OF PEG 7 GLYCERYL COCOATE:
*universal, effective emollient and conditioning agent in washable cosmetics,
*smoothes the skin and hair,
*very good emulsifying and washing properties,
*compatibility and synergism of action with anionic and amphoteric surfactants,
*foam stabilizer,
*acts as co-emulsifier,
*stabilizes oil-in-water (O / W) emulsions,
*biodegradable and well tolerated by the skin and mucous membranes,
*based on renewable vegetable raw materials.



SAFETY PROFILE OF PEG 7 GLYCERYL COCOATE:
PEG-7 Glyceryl Cocoate is safe for use in rinse-off products such as cleansers and shampoos.
PEG 7 Glyceryl Cocoate can also be used in leave-on products up to a concentration of 10%.
Additionally, PEG 7 Glyceryl Cocoate is non-comedogenic and does not clog pores or cause acne.



PHYSICAL and CHEMICAL PROPERTIES of PEG 7 GLYCERYL COCOATE:
pH: 5.0-8.0
Solubility: Soluble in water
Viscosity: Low
Appearance, Physical State: Liquid
Odor: Mild
Taste: Not available
Color: Pale yellow
Molecular Weight: Not available
pH (3% sol. in water) 6.0-7.5
Boiling Point: Not available
Melting Point: 25°C
Vapor Pressure: Not available
Vapor Density: Not available
Evaporation Rate: Not available
Flammability: Not available
Upper/lower Explosive Limit: Not available
Solubility: Soluble in water
Flash Point: Not available
Specific Gravity: 1.064



FIRST AID MEASURES of PEG 7 GLYCERYL COCOATE:
*Eyes:
Immediate medical attention is required.
Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.
*Inhalation:
Move to fresh air.
Immediate medical attention is required.
*Skin:
Wash off immediately with soap and plenty of water while removing all contaminated clothing and shoes.
Obtain medical attention.
Take off contaminated clothing and shoes immediately.
*Ingestion:
Drink plenty of water.
If possible, drink milk afterwards.
Call a physician immediately



ACCIDENTAL RELEASE MEASURES of PEG 7 GLYCERYL COCOATE:
-Personal precautions, protective,equipment and emergency procedures:
(Methods and materials for containment and cleaning up)
Keep unnecessary personnel away.
Ventilate closed spaces before entering them.
Absorb with inert absorbent such as dry clay, sand or diatomaceous earth, commercial sorbents, or recover using pumps.
Dike the spilled material, where this is possible.
Prevent product from entering drains.
*Large Spills:
Dike the spilled material, where this is possible.
Cover with plastic sheet to prevent spreading.
Absorb in vermiculite, dry sand or earth and place into containers.
*Small Spills:
Wipe up with absorbent material (e.g. cloth, fleece).
-Environmental precautions:
Retain and dispose of contaminated wash water.
Contact local authorities in case of spillage to drain/aquatic environment.
Prevent further leakage or spillage if safe to do so.



FIRE FIGHTING MEASURES of PEG 7 GLYCERYL COCOATE:
-Suitable extinguishing media:
Water spray, fog, CO2, dry chemical, or alcohol resistant foam.
-Fire fighting instructions:
Specific methods:
Use water spray to cool unopened containers.



EXPOSURE CONTROLS/PERSONAL PROTECTION of PEG 7 GLYCERYL COCOATE:
-Biological limit values:
No biological exposure limits noted for the ingredient(s).
-Individual protection measures, such as personal protective equipment:
*Eye/face protection:
Wear safety glasses with side shields (or goggles).
*Skin protection:
**Hand protection:
Chemical resistant gloves.
**Other:
Wear suitable protective clothing.
*Respiratory protection:
Respiratory protection not required.
*Thermal hazards:
Wear appropriate thermal protective clothing, when necessary.
*General hygiene considerations:
Always observe good personal hygiene measures, such as washing after handling the material and before eating, drinking, and/or smoking.
Routinely wash work clothing and protective equipment to remove contaminants.



HANDLING and STORAGE of PEG 7 GLYCERYL COCOATE:
-Precautions for safe handling:
Do not handle or store near an open flame, heat or other sources of ignition.
Take precautionary measures against static discharges.
All equipment used when handling the product must be grounded.
Wash thoroughly after handling.
-Conditions for safe storage, including any incompatibilities:
Keep container closed.
Handle containers with care.
Open slowly in order to control possible pressure release.
Store in a cool, well-ventilated area.



STABILITY and REACTIVITY of PEG 7 GLYCERYL COCOATE:
-Reactivity:
Stable under normal conditions
-Chemical Stability:
Stable under normal conditions
-Hazardous Polymerization:
Will not occur
-Conditions to Avoid:
No additional precautions
-Special Remarks:
None



SYNONYMS:
Glycerides
coco mono- and di-
ethoxylated
Glycerides, coco mono- and di-, ethoxylated
PEG-7 Glyceryl Cocoate
macrogoli 7 glyceroli cocoas
Cetiol He
Polyoxyethylen(7) Glycerylcocoat
peg-7 Glyceril Cocoate
GLYCERYL OLEATE
GLYCERIN

cas no 25322-68-3 PEG; Poly(ethylene glycol); PEG 8000;

PEG, Poly(ethylene glycol), peg 8000, cas no : 25322-68-4; PEG, Polymère d'oxyéthylène, alpha-hydro-oméga-hydroxypoly(oxy-1,2-éthynediyl),poly(oxyde d'éthylène), poly(oxyéthylène), PEG, PEO, No Cas: 25322-68-3; PEG, Polymère d'oxyéthylène,alpha-hydro-oméga-hydroxypoly(oxy-1,2-éthynediyl),poly(oxyde d'éthylène), poly(oxyéthylène), PEG, PEO, Le PEG est utilisé dans de nombreux secteurs de l'industrie. Il sert par exemple comme épaississant ou gélifiant à la base de nombreux produits cosmétiques (savons liquides, crèmes hydratantes, shampoings, etc.) et paramédicaux (gels hydroalcooliques, lubrifiants intimes, etc.). Il est également utilisé comme solvant dans les encres pour imprimantes ou pour fabriquer des billes de paint-ball, ou bien comme additif alimentaire et dans certaines résines polyesters.Poly(ethylene glycol), Poly(oxy-1,2-ethanediyl),.alpha.-hydro-.omega.-hydroxy; Poly(oxy-1,2-ethanediyl),α-hydro-ω-hydroxy- Ethane-1,2-diol; Poly(oxy-1,2-ethanediyl),α-hydro-ω-hydroxy-Ethane-1,2-diol, ethoxylated;poly(oxyethylene); POLYETHYLENE GLYCOL

PEG-10 LAURATE, N° CAS : 9004-81-3. Origine(s) : Synthétique. Nom INCI : PEG-10 LAURATE. Classification : PEG/PPG, Composé éthoxylé, Glycol, Polymère de synthèse. Ses fonctions (INCI). Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile)

PEG-10 Stearate is a polyethylene glycol ester of stearic acid.
Peg-10 Stearate is a white to pale yellow liquid, petrolatum-like or waxy substance



CAS Number: 9004-99-3
EC Number: 618-405-1
Chem/IUPAC Name: Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy- (10 mol EO average molar ratio)
Origin(s): Synthetic
INCI name: PEG-10 STEARATE
Classification: PEG/PPG , Ethoxylated compound , Glycol , Synthetic polymer



NIKKOL MYS-10V, Protamate DPS(TM), PEG-4 Stearate(TM), 13149-87-6, CTAETHYLENE GLYCOL OCTADECYL ETHER, Octadecyloctaglycol, Octaethylene glycol monooctadecyl ether, 2-[2-[2-[2-[2-[2-[2-(2-octadecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol, 3,6,9,12,15,18,21,24-Octaoxadotetracontan-1-ol, Octadecyl octaethylene glycol ether, SCHEMBL62047, DTXSID70157070, MFCD00043374, AKOS015902799, J-006013, Octaethylene glycol monooctadecyl ether, BioXtra, >=98.0% (TLC), PEG-100 STEARATE, Polyethylene glycol monostearate, PEG-75 STEARATE, POES, polyoxyl, polystate, PEG-150 STEARATE, POLYOXYL 50 STEARATE, POLYOXYETHYLENE 8 STEARATE, Polyoxyl 100 Stearate (200 mg)



Peg-10 Stearate is created by attaching ten water-loving glycerin molecules with the oil-loving fatty acid, stearic acid.
The result is a partly water- and partly oil-loving molecule that creates stable and smooth emulsions that are also cosmetically elegant.
Peg-10 Stearate also has some moisturizing and softening benefits for skin and hair.


Peg-10 Stearate is a white to pale yellow liquid, petrolatum-like or waxy substance
Peg-10 Stearate is a hydrophilic emulsifier; plant-derived
Peg-10 stearate is a white waxy solid, soluble in isopropanol, mineral oil butyl stearate, glycerin, peroxyethylene, gasoline solvent, dispersed in water.


PEG-10 Stearate is a polyethylene glycol ester of stearic acid.
Peg-10 Stearate is a Hydrophilic emulsifier; plant-derived.
Chemical Class of Peg-10 Stearate is Polyoxyethylene Glycol Fatty Acid Esters.


"PEG" refers to a PEG-(polyethylene glycol-) derivative.
The number behind "PEG-" (or the first number behind "PEG/...-") refers to the average number of molecular units -CH2-CH2-O-.
Stearates are salts or esters of stearic acid (octadecanoic acid).



USES and APPLICATIONS of PEG-10 STEARATE:
Industry Primarily Used of Peg-10 Stearate: Cosmetics, Pharmaceuticals, and Inks & Coatings.
Peg-10 Stearate is used Face toners, aftershaves and hair tonics, as solvent and solubiliser for active ingredients, perfume oils and colourants, humectants, basis for creams, as consistency enhancer, binding agent, softening agent and fixative


Peg-10 Stearate is a vegetable-based, PEG-free ingredient whose job is to help water and oil to mix nicely together (emulsifier).
Peg-10 stearate is used in cosmetics, pharmaceutical emulsifiers, soap-based thickeners, softeners, emulsion stabilizers, etc
Peg-10 stearate is used Polyethylene Glycols, Nonyl Phenol Ethoxylates, Personal Care.
Peg-10 stearate is used cleaning and Detergents.



FUNCTIONS OF PEG-10 STEARATE:
*Emulsifying agent:
Peg-10 Stearate promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil)
*Surfactant:
Peg-10 Stearate reduces the surface tension of cosmetics and contributes to the uniform distribution of the product during use



WHAT DOES PEG-10 STEARATE DO IN A FORMULATION?
*Emulsifying
*Surfactant



FUNCTIONS OF PEG-10 STEARATE IN COSMETIC PRODUCTS:
*SURFACTANT - EMULSIFYING
Peg-10 Stearate allows the formation of finely dispersed mixtures of oil and water (emulsions)



FUNCTIONS OF PEG-10 STEARATE:
1. Anti-foaming Agent / Defoamer:
Peg-10 Stearate reduces or hinders the formation of foam.
2. Binder / Stabilizer:
Peg-10 Stearate retains the physical characteristics of food/cosmetics and ensure the mixture remains in an even state.
3. Emulsifier:
Peg-10 Stearate allows water and oils to remain mixed together to form an emulsion.
4. Surfactant:
Peg-10 Stearate reduces the surface tension to allow mixtures to be formed evenly.
Emulsifier is a specific type of surfactant which allows two liquids to mix together evenly
Peg-10 Stearate is an ester of Stearic Acid (a naturally occurring fatty acid).
Peg-10 Stearate is also referred to as Polyoxyethylene Stearate. Polyethylene Glycol is made from Ethylene Glycol monomers.
Peg-10 Stearate then reacts with Stearic Acid to form Polyethylene Glycol Stearate.
As a food additive, Peg-10 Stearate has E number 431.
Peg-10 Stearate can be found in bread to give a soft texture and may also be found in some wines.
Peg-10 Stearate is approved to use as food additive in EU.



WHAT IS PEG?
Polyethylene Glycol (PEG) Stearates (PEG-2 Stearate, PEG-6 Stearate, PEG-8 Stearate, PEG-12 Stearate, PEG-20 Stearate, PEG-32 Stearate, PEG-40 Stearate, PEG-50 Stearate, PEG-100 Stearate, PEG-150 Stearate) are esters of polyethylene glycol and stearic acid.
The PEG Stearates are soft to waxy solids that are white to tan in color.
In cosmetics and personal care products, PEG Stearates are used in skin creams, conditioners, shampoos, body cleansers and soapless detergents.



WHY IS PEG USED?
The PEG Stearates clean the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away.



SCIENTIFIC FACTS OF PEG-10 STEARATE :
The PEG Stearates are produced from stearic acid, a naturally occurring fatty acid
A natural organic compound that consists of a carboxyl group (oxygen, carbon and hydrogen) attached to a chain of carbon atoms with their associated hydrogen atoms.

The chain of carbon atoms may be connected with single bonds, making a ‘saturated’ fat; or it may contain some double bonds, making an ‘unsaturated’ fat.
The number of carbon and hydrogen atoms in the chain is what determines the qualities of that particular fatty acid.
Animal and vegetable fats are made up of various combinations of fatty acids (in sets of three) connected to a glycerol molecule, making them triglycerides.

The numerical value of each PEG Stearate corresponds to the average number of ethylene oxide monomers in the polyethylene chain.
Polyethylene glycol ingredients may also be named with a number that indicates molecular weight, for example polyethylene glycol (400) stearate is another name for PEG-8 Stearate.



PHYSICAL and CHEMICAL PROPERTIES of PEG-10 STEARATE:
INCI Name: Polyoxyethylene Stearate
Appearance: White to yellowish solid
Acid Value（mg KOH/g）: ≤1.0
Sapon Value（mg KOH/g）：≤15.0
Product Name: Polyethylene glycol monostearate
CAS No.: 9004-99-3
Molecular Formula: (C2H4O)nC18H36O2
InChIKeys: InChIKey=RFVNOJDQRGSOEL-UHFFFAOYSA-N
Molecular Weight: 328.53000
Exact Mass: 328.29800
EC Number: 926-608-4
HScode: 3907200000
Categories: Emulsifier
CAS: 9004-99-3
EINECS: 618-405-1
InChI: InChI=1/C20H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)23-19-18-21/h21H,2-19H2,1H3

Molecular Formula: C34H70O9
Molar Mass: 622.91
Melting Point: 47 °C
Flash Point: 39 °C
Water Solubility: Soluble in water
Appearance: powder to lump
Color: White to Almost white
Storage Condition: 2-8°C，
MDL: MFCD00043374
Molecular Weight: 622.9 g/mol
XLogP3: 7.3
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 9
Rotatable Bond Count: 40

Exact Mass: 622.50198381 g/mol
Monoisotopic Mass: 622.50198381 g/mol
Topological Polar Surface Area: 94.1Ų
Heavy Atom Count: 43
Formal Charge: 0
Complexity: 471
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes



FIRST AID MEASURES of PEG-10 STEARATE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of PEG-10 STEARATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of PEG-10 STEARATE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of PEG-10 STEARATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of PEG-10 STEARATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
*Storage stability:
Recommended storage temperature: 2 - 8 °C



STABILITY and REACTIVITY of PEG-10 STEARATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available

Peg-100 is a white to light yellow substance with a faint but characteristic odour.
Peg-100 is also soluble in organic liquids such as methanol, ethanol, chloroform or ethylene glycol.


CAS Number: 25322-68-3
EC Number: 500-038-2


Peg-100's density at 70ᵒC is about 1.08 g/ml.
Peg-100 molecules ignite and decompose above 220ᵒC.
Peg-100 is a white to light yellow substance with a faint but characteristic odour.


Peg-100 is soluble in water or ethanol, insoluble in ether.
The freezing point of Peg-100 is 33~38°C.
Similar to other compounds belonging to the broad PEG group, this surfactant, Peg-100, dissolves very well in water.


Ultrapure white crystals for molecular biology applications such as precipitation of DNA, nucleic acids, hybridization and fusion of mammalian cells.
Working concentrations of Peg-100 range from 13% to 40% (w/v).
Prepare the appropriate concentration by dissolving Peg-100 in sterile H2O, warming if necessary.


Sterilize the solution by passing Peg-100 through a 0.22-μm filter.
Peg-100 stores the solution at room temperature.
Peg-100 is also soluble in organic liquids such as methanol, ethanol, chloroform or ethylene glycol.


The molar mass of PEG-100 is approx. 4500 g/mol.
Peg-100 is a thermoplastic resin with good compatibility with other resins.
Resistant to bacterial erosion, moisture absorption in the atmosphere is weak.


Peg-100 is a mixture of ethylene oxide and water polycondensation.
Peg-100 is a colorless or almost colorless viscous liquid, or a translucent waxy soft object; slightly odorless.
Peg-100, a hydrophilic polymer, is easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups.


Peg-100 is a yellowish wax-like solid at room temperature.
Peg-100 is soluble in water and polar organic solvents like acetone or methanol.
Peg-100 is insoluble in pure hydrocarbons.


Peg-100 is suitable for paints and coatings.
Peg-100 is a non-volatile solvent, release agent, lubricant and plasticizer.
The pH of a 10% aqueous solution ranges from 4.6 to 7.4.


The hydroxyl number for PEG-100 is 23 to 28 mg KOH/g.
Peg-100 is used as a base in the formulation of soap sticks.
Peg-100 has low glycol content and higher crystalinity.


Peg-100 is a polyethylene glycol-based solvent, humectant and plasticizer.
Peg-100 possesses very low water content and good solubility in water.
Peg-100 is a solid in powder form.


The physical and chemical properties of polyethylene glycols are mainly determined by the two hydroxyl end groups, the ether groups as well as the molecular weight.
Peg-100 shows typical chemical reactions of alcohols/diols and a very low evaporation rate.


The solidification point of Peg-100 is about 58 °C.
Peg-100 is a non-volatile solvent, release agent, lubricant and plasticizer.
Peg-100 is safe, non-toxic and non-irritating.


Peg-100 is suitable as a medium for the fusion of mammalian cells.
Peg-100 has a wide range of uses including cell fusion for the formation of hybridomas, precipitation of DNA, and to create macromolecular crowding in solutions.


Peg-100 is white granular.
Peg-100 is soluble in water, soluble in some organic solvents.
Peg-100 is hygroscopic.


Peg-100 is water soluble and also soluble in many organic solvents like aromatic hydrocarbons.
Peg-100 is a milled PEG excipient grade powder product, produced under IPEC GMP conditions.
Peg-100 supports the homogeneous mixing with other materials within production.


Peg-100 is compatible with cellulose, rubber, polyester and polyurethane.
Peg-100 is Suitable for use in papers, adhesives and sealants.
Peg-100 shows typical chemical reactions of alcohols/diols and a very low evaporation rate.


Peg-100 has very low water content and outstanding toxicological safety.
Peg-100 is compatible with hard water, cellulose, polyester, rubber, elastomer and polyurethane.
Glyceryl stearate is created by the esterification of glycerin and stearic acid. and then combined with Peg-100 to add the final stability of the emulsion, increasing the emulsions ability to absorb additional ingredients such as essential oils and colourings.


Peg-100 is soluble in water and polar organic solvents like acetone or methanol.
Peg-100 is insoluble in pure hydrocarbons.
Peg-100 acts as a solvent and plasticizer.


Peg-100 shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Peg-100 is a yellow solid in fine powder form.
Peg-100 is a solid in powder form.


Peg-100 is specified according to the requirements of the main international ICH guidelines and monographs.
Peg-100 shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Peg-100 is compatible with hard water, cellulose, polyester, rubber, elastomer and polyurethane.


Peg-100 is quite stable and does not support microbial growth, even in aqueous solutions.
Ultrapure white crystals for molecular biology applications such as precipitation of DNA, nucleic acids, hybridization and fusion of mammalian cells.
Peg-100 is soluble in water (500 g/l at 20° C), aromatic hydrocarbons (very soluble), aliphatic hydrocarbons (slightly soluble), and organic solvents.


Peg-100 is a water-soluble, waxy solid that is used extensively in the several industries.
Peg-100 is a polyethylene glycol having white to off white color and available in solid flakes or powder form.
Peg-100 can blend with other PEG molecular weights to achieve the desired viscosity properties.


Peg-100 is soluble in water.
Peg-100 is store at room temperature.
The solution has high viscosity at low concentration, and Peg-100 can be processed by calendering, extrusion, casting, etc.


The molecular formula is expressed as HO(CH2CH2O)nH, where n represents the average number of oxyethylene groups.
On being incorporated into networks by crosslinking, Peg-100 can have high water content, forming “hydrogels”.
Hydrogel formation can be initiated by either crosslinking it by ionizing radiation or by covalent crosslinking of Peg-100 macromers with reactive chain ends.



USES and APPLICATIONS of PEG-100:
Peg-100 is used in household chemicals.
Peg-100 is used as mold release agent and lubricant in fabricating elastomers.
Peg-100 is a safe solvent and carrier for use in cosmetics can act as a solvent in many substances.


Peg-100 is also a secure carrier.
Peg-100 is used as antistatic agent and lubricant in textile industry.
Peg-100 is a safe solvent and carrier for use in cosmetics can act as a solvent in many substances.


Peg-100 is also a secure carrier.
Peg-100 is a popular additive for detergents such as dishwasher or laundry tablets.
Peg-100 is also used to precipitate bacteriophage from lysed cell supernatants.


Peg-100 is often used as a polar stationary phase for Gas Chromatorgraphy.
Peg-100 is commonly also used in mass spec experiments.
Peg-100 is used as Solvent / Humectant / Plasticizer: Paper, wood, cellulose films, inks, paints, coatings, adhesives, and sealants, concrete.


Peg-100 is used Hair Conditioner, Cleaning Agent, Bath Oils, Tablets & Salts, Hair Styling Products, Detanglers, Antiperspirants & Deodorants, Anti-Aging Products, Cosmetics, Detergents in the form of tablets, Production of packaging, Metalworking, Construction industry, Textile industry, Processing of plastics and elastomers, Production of ceramics, and Coatings.


Peg-100 is used as Release agent: Lubricant mould release agent for rubber and elastomer processing, lubricant formulations, metal working fluids.
Peg-100 is used as a binding agent and carrier of active substances.
Peg-100 is used Binder for ceramics, Component of auxiliaries for fiber, textile and leather processing, and Heat transfer medium.


Besides cosmetics and detergents, Peg-100 is a popular surfactant used in metalworking processes.
Peg-100 is used in the modification of therapeutic proteins and peptides to enhance it's solubility.
In gas chromatography, Peg-100 is used as a polar stationary phase.


Peg-100 finds application in blood banking as a potentiator, which is used to detect antigens and antibodies.
Peg-100 is a suitable compound with a wide scope in biological applications since Polyethylene glycol 8000 does not elicit any immune responses.
Peg-100 has been shown to modify therapeutic proteins and peptides for enhanced solubility.


Peg-100 is used as a component of lubricants, primarily water-soluble synthetic working fluids and heat transfer fluids.
The use of working fluids containing Peg-100 helps transfer heat generated during machining metal parts.
Peg-100 for the plastics industry is an anti-adhesive agent used in rubber and elastomer processing.


Peg-100 is used Laboratory chemicals, Manufacture of substances, Adhesives, Ceramic Binder, Chemical Intermediates, Detergents and Household Cleaners, Dye Carrier, Lubricants, Mining, Mold Release Agent, Plasticizer, Wood Treating, Rubber, Textile, Paper, Metal, Wood, Pharmaceutical, Cosmetics, and Coating.
Peg-100 has a positive opinion of an international organization, namely the FDA (Food and Drug Administration).


Additionally, photopolymerized Peg-100 hydrogels have emerging applications in the fabrication of bioactive and immune-isolating barriers for encapsulation of cells.
Peg-100 is vastly used for the isolation of plasmid DNA and the precipitation of phage.


Peg-100 is a polyethylene glycol-based solvent, humectant and plasticizer.
As a dispersant, Peg-100 is used in toothpastes.
In fabricating elastomers, Peg-100 can be used as a lubricant and mold releasing agent.


Anti-adhesive agents on the surface of the materials reduce their adhesion to the mold and thus facilitate the removal of rubber or plastic molds.
Compounds such as Peg-100 are essential for the processing of the rubber industry as they speed up processes and increase their efficiency.
In pharmaceuticals, Peg-100 can function as a tablet and capsule lubricant.


Peg-100 is used for the isolation of plasmid DNA and the precipitation of phage.
Peg-100 is used as matrix in pharmaceutical and cosmetic industry to regulate viscosity and melting point.
The FDA has approved the use of surfactant of Peg-100 as an indirect food additive.


Peg-100, NF acts as a lubricant, coating the surfaces in aqueous and non-aqueous environments.
Peg-100 can be easily applied and removed since they are water-soluble.
Peg-100 are also used as binder and dry lubricant for manufacturer of pills and tablets for certain pharmaceutical products.


Peg-100 is used in the production of biopolymer-based food packaging.
Research or further manufacturing, Peg-100 is used only, not for food or drug use.
Peg-100 is widely used as a mould release agents and lubricants for rubber industry.


Peg-100 is also used to preserve objects that have been retrieved from the ocean.
Crystallization grade Peg-100 for formulating screens or for optimization.
In pharmaceutical industry, Peg-100 is used as tablet and capsule lubricant.


Peg-100 is also used in the fabrication of bioactive and immuno isolating barriers for encapsulation of cells.
Peg-100 should be used as recommended and the maximum allowable dose should not be exceeded.
Peg-100 that has wide application ranging from industrial manufacturing and medicine.


Peg-100 is a compound used to modify therapeutic proteins and peptides to increase their solubility.
Peg-100 are produced to meet the requirements for use under Food Additive Regulations for indirect use as components of articles intended for use in contact with food.


Peg-100 is a surfactant used in the household chemicals, ceramics, paper, cosmetic and metal industries.
Peg-100 possesses very low water content and good solubility in water.
Peg-100 is used Washing powders and tabs, Dissolving aids, Tabletting and granulation auxiliaries, Binding agents, and Toilet blocks.


Peg-100 is used as Reactant: Reactive diol/polyether component in polyester or polyurethane resins
Peg-100 is generally used in the precipitation of phage.
Peg-100 acts as a plasticizer, anti-adhesive, binding agent and moisturizing agent in products.


Peg-100's high molecular weight mainly prompts its use in pharmaceutical formulations as solvent for oral, topical and parenteral preparations.
Peg-100 is used as lubricant and coolant in rubber and metal processing industry, dispersant and emulsifier in pesticide and pigment industry production.
Peg-100 is used as a solvent (solvent) or a conductor (carrier) in all kinds of cosmetics.


You can find Peg-100 in products such as cosmetics, food packaging, detergents or additives for processing plastics.
The polyethylene glycol polymers are used in a wide variety of products including bath products, shaving products, skin care products, makeup, skin cleansing products, shampoo, hair conditioners and deodorants.


PEG is widely used in various fields, from industrial manufacturing to medicine.
PEG has excellent lubricity, moisturizing, dispersion, adhesion, can be used as an antistatic agent and softener, and has a wide range of applications in cosmetics, pharmaceuticals, chemical fiber, rubber, plastics, papermaking, paint, electroplating, pesticides, metal processing and food processing industries.


Polyethylene glycol is a polymer with the chemical formula HO (CH2CH2O)nH, non-irritating, slightly bitter taste, good water solubility, and good compatibility with many organic components.
Peg-100 is also used as a fusogen (induces cell hybridization) to obtain hybridomas for monoclonal antibody production.


PEG has excellent lubricity, moisturizing, dispersion, adhesion, can be used as an antistatic agent and softener, and has a wide range of applications in cosmetics, pharmaceuticals, chemical fiber, rubber, plastics, papermaking, paint, electroplating, pesticides, metal processing and food processing industries.


-Medical uses of Peg-100:
*Widely used in pharmaceutical formulations.
*Used as the basis of a number of laxatives.
*Used as an excipient in many pharmaceutical products.
*Possibly used to fuse axons.
*Used to synthetic lubricant.
*Used as solvent to prepare water-soluble drugs.
*Used to modify medical polymer materials.
*Used as linkers for antibody-drug conjugates (ADCs).
*Used as a surface coating on nanoparticles to improve systemic drug delivery.
*Frequently used in many biomedical applications, including but not limited to bioconjugation, drug delivery, surface functionalization and tissue engineering.


-Applications of Peg-100:
*body cosmetics (creams, toothpastes, foundations, masks, coloring creams)
*hair cosmetics (sprays, gels, conditioners and dyes)
*preparations used after tanning
*binder for soaps
*fixative for fragrances
*tire production
*additive to flexographic inks
*wood processing


-Peg-100 resins are high molecular weight homopolymers of ethylene oxide via heterogeneously catalyzed ring-opening polymerization.
Usually can be divided into the relative molecular mass of 2 × 1 04 above and tens of thousands of above, the former is called polyethylene glycol, the latter is called polyethylene oxide.
Polyethylene oxide with flocculation, thickening, slow release, lubrication, dispersion, retention, water retention and other properties, suitable for medicine, fertilizer, paper, ceramics, detergents, cosmetics, heat treatment, water treatment, fire, oil exploitation and other industries, the product is non-toxic and non-irritating, and will not remain, deposit or breed volatile matter in the process of product generation.
As a papermaking additive, the retention rate of the filler and the fine fiber can be improved, and the dispersant is particularly suitable for the long fiber, and the beating time can be shortened.


-Usage areas of Peg-100:
*Degreasers
mineral oil emulsifier
*Lubricating and antistatic in textile yarn oils
*Pigment printing thickener and emulsifier
*Pigment dispersion
ink organic pigment dispenser
*Pesticide (pesticide, herbicide, fungicide) emulsifier
*Mold release agents
*Metalworking fluids
*Wetting and dispersing in inks and coatings
viscosity adjuster
*In defoamer prescriptions
*Regulator and binder in latex paints
*Dispersant, wetting agent and binder in water and solvent based coatings
*Emulsifier, moisturizer in cosmetic products
*Blend oil emulsifiers


-Chemical uses of Peg-100:
*Used as lubricating coating for various surfaces.
*Used to create high osmotic pressure.
*Used to passivate microscope slides.
*Used to preserve objects salvaged from underwater.
*Used to preserve the color of painting.
*Used as heat transfer fluid in electronic testers.
*Used as the polar stationary phase of gas chromatography.
*Used as an internal calibration compound in mass spectrometry experiments.


-Biological uses of Peg-100:
*Used as a crowding agent in vitro to simulate highly crowded cellular conditions.
*Used as a precipitant for plasmid DNA isolation and protein crystallization.
*Used for cell fusion.
*Used for virus concentratation.
*Used to coat gene therapy vectors to protect them from inactivation by the immune system.
*Used to package siRNA for in vivo use.
*Used as a potentiator to enhance detection of antigens and antibodies in blood banking.
*Used in the functioning ion channels diameter studies to block ion channel conductance.


-Peg-100 is a polyethylene glycol that is used for a wide variety of applications including:
*Reactive diol/polyether component in polyester or polyurethene resins
*Component of auxiliaries for leather and textile processing
*Cosmetic / pharmaceutical formulations (e.g. humectant or solubilizer for creams, shampoos, tooth paste)
*Lubricant and mould release agent for rubber, plastic and elastomer processing
*Plasticizer and binder for ceramic and concrete manufacturing
*Component of lubricant formulations
*Water soluble, lubricating component in metalworking fluids
*Humectant for paper, wood and cellulose films
*Solvent and humectant for dyes and inks
*Modifier for production of regenerated viscoses
*Humectant and plasticizer for adhesives.


-Peg-100 to Use in:
*Moisture Cream
*Moisture Lotion
*Body Butter
*Cleanser
*Face Mask
*Skin Peels
*Shower Gel
*Shampoo
*Conditioner


-The kinetic of the ligation in the cloning of DNA-fragments into bacteriophage M13-vectors can be improved by the inclusion of 5% Peg-100.
Especially for the cloning with 'blunt-ended' DNA, the concentration of 'blunt'-DNA-ends plays a crucial role for the successful cloning.
Substances, that increase the so-called 'macromolecular crowding' and condense DNA molecules into aggregates, concentrate the
DNA and increase the possibility, that DNA ends will meet and thereby improve the cloning result.
So, the DNA and enzyme concentration can be reduced.
Besides, such substances reduce the intramolecular ligation (religation).
For 'blunt end' cloning the recommended Polyethylene glycol 8000 concentration is 15%.
Stock solutions of Peg-100 (40%) are prepared with deionized water and stored at -20°C in small aliquots.



EFFECTS OF PEG-100 IN COSMETIC AND INDUSTRIAL APPLICATIONS:
Peg-100 is used as a surfactant in the cosmetic industry.
Peg-100's unlimited water solubility is used in the design of what are known as hard cosmetics, such as lipsticks.
Peg-100 is used as their component.
When used as a moisturizer in cosmetic products, Peg-100 also retains water.
You can find Peg-100 in products such as creams, face washes, scrubs or makeup removers.
Peg-100 is also used to increase the viscosity (improve its performance and application properties) of a cosmetic formulation, i.e. to change its rheology.



FUNCTION of PEG-100:
-Binder
-Carrier
-Anti-Static Agent
-Moisturizing Agent
-Humectant
-Plasticizer
-Solvent
-Solubilizer
-Slip Agent
-Viscosity Modifier



CHARACTERISTICS OF PEG-100:
The high quality glyceryl stearate emulsion has a higher humectant level than standard glyceryl stearate and can aid the feel of the final product.



FEATURES OF PEG-100:
Peg-100 is the INCI name for a compound whose chemical name is polyoxyethylene glycol.
The CAS number of Peg-100 is 25322-68-3 .
Peg-100 is mostly used in various applications where it acts as an emulsifier and wetting agent.



ADVANTAGES RESULTING FROM THE USE OF PEG-100:
Its main advantages are as follows:
*unique softening, lubricating and moisturizing properties,
biodegradability,
*a wide range of applications,
*a suitable physical form that facilitates handling under industrial conditions,
*unlimited water solubility,
*non-toxic.



PRODUCT TYPE of PEG-100:
*Humectants
*Plasticizers
*Solvents > Glycols & Glycol Ethers > Ethylene Glycols
*Lubricants / Waxes
*Other Additives for Liquid Systems > Solvents > Glycols
*Plasticizers
*Release Agents



BENEFITS OF PEG-100:
*safe, non-toxic substance
*unlimited solubility in water
*has hygroscopic properties
*binder
*protects against excessive moisture absorption
*stable in hard water
*it has solubilizing, softening, lubricating and moisturizing properties
*biodegradable



GLYCERYL STEARATE & PEG-100:
Glyceryl stearate is created by the esterification of glycerin and stearic acid and then combined with Peg 100 to add the final stability of the emulsion, increasing the emulsions ability to absorb additional ingredients such as essential oils and colourings.



CHARACTERISTIC OF PEG-100:
. Highly compatible to various kinds of organic compounds.
. High boiling point.
. Easy control of the degree of condensation.
. Controllable hygroscopic property.
. Less toxicity, PEG is characterized by less toxicity and less skin irritation.
. There is no damage in case of contact with skin or lips.



BENEFITS of PEG-100:
-Good solubility in water
-Very low water content
-Compatible with hard water
-Non-volatile
-Outstanding toxicological safety



WHAT IS PEG?
Triethylene Glycol and other polyethylene glycols (PEG-4, PEG-6, PEG-7, PEG-8, PEG-9, PEG-10, PEG-12, PEG-14, PEG-16, PEG-18, PEG-20, PEG-32, PEF-33, PEG-40, PEG-45, PEG-55, PEG-60, PEG-75, PEG-80, PEG-90, PEG-100, PEG-135, PEG-150, PEG-180, PEG-200, PEG-220, PEG-240, PEG-350, PEG-400, PEG-500, PEG-800, PEG-2M, PEG-5M, PEG-7M, PEG-9M, PEG-14M, PEG-20M, PEG-23M, PEG-25M, PEG-45M, PEG-65M, PEG-90M, PEG-115M, PEG-160M, PEG-180M) are polymers of ethylene glycol.

The number in the name represents the average number of ethylene glycol units.
The letter associated with the number stands for 1000, so PEG-25M has an average of 25,000 units of ethylene glycol.
Different molecular weight polyethylene glycol has different morphology.

Polyethelene glycol (PEG) is a synthetic, hydrophilic, biocompatible polyether, which is consist of a (−O−CH2−CH2−) backbone.
Its structure is commonly expressed as H−(O−CH2−CH2)n−OH.
Depending on the molecular weight, PEG is also known as polyoxyethylene (POE) or polyethylene oxide (PEO).
PEGs can be synthesized in linear, branched, Y-shaped, or multi-arm geometries.

PEGs can be activated by replaing the terminal hydroxyl end group with various reactive functional end groups enabling crosslinking and conjugation chemistries.
Polyethylene glycol is a polymer with the chemical formula HO (CH2CH2O)nH.



PEG (ETHYLENE GLYCOL) ESTERS:
*PEG 200, PEG 300, PEG 400, PEG 600 Mono and Dioleate
*PEG 200, PEG 300, PEG 400, PEG 600 Mono and dicocoate
*PEG 200, PEG 300, PEG 400, PEG 600 Mono and dilaurate
*PEG 200, PEG 300, PEG 400, PEG 600 Mono and di tall oil fatty acid

Polyethylene glycol esters composed of polyethylene glycol (peg) and fatty acid have various lipophilic-hydrophilic values depending on different peg and fatty acid molecular weights.
Depending on this value, they ensure that water can be emulsified in oil or oil in water.
*Emulsifying oils
*Wetting and lubrication
*Biodegradability
*low toxicity
*not foaming
*Antistatic.



PHYSICAL and CHEMICAL PROPERTIES of PEG-100:
Appearance Form: solid
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available



FIRST AID MEASURES of PEG-100:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of PEG-100:
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of PEG-100:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of PEG-100:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Choose body protection in relation to its type.
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
No special environmental precautions required.



HANDLING and STORAGE of PEG-100:
-Precautions for safe handling:
*Hygiene measures:
General industrial hygiene practice.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage stability:
Recommended storage temperature: 2 - 8 °C



STABILITY and REACTIVITY of PEG-100:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
PEG
Poly(ethylene glycol)
Polyethyleneglycol 8000
Macrogol 8000
Macrogols 8000
Poly(ethylene glycol)
Polyethyleneglycol 8000
PEG 8k
Polyethylene glycol
Poly(ethylene glycol)
Polyethylene glycol
polyethylene oxide standard 511000
Poly(ethylene oxide)
macrogol
poly(oxyethylene)
Polyethylene glycol PEG
Aquacide III
PEG 1000
PEG 6000, MB Grade (1.12033)
Ethylene glycol 8000 polymer
Polyethyleneglycol
Polyethylene Glycol 5000000
PolyethyleneoxideMW
PEG 200-8000
Tri-(2,3-Dibromopropyl) Phosphate
Polyethylene glycol - 6000 grade
PEG 200
PEG 400
PEG 6000
Poly(ethylene oxide)
PEO
PEG 600
Polyethyleneoxidemonomethacryloxymonotrimethylsiloxyterminated
O-Methacryloxy(polyethyleneoxy)trimethylsilane
PEG
Poly ethylene glycol
Carmowax
carbowax
PEG 8000
Polyethylene glycol series
Polyethylene Glycol
Polyethylene glygcol

PEG-12 Distearate; PEG-150 Distearate; PEG-3 Distearate; PEG-32 Distearate; PEG-6 Distearate cas no: 25322-68-3

PEG-12 GLYCERYL DIMYRISTATE Origine(s) : Synthétique Nom INCI : PEG-12 GLYCERYL DIMYRISTATE Classification : PEG/PPG, Composé éthoxylé, Glycol, Polymère de synthèse Ses fonctions (INCI) Agent d'entretien de la peau : Maintient la peau en bon état

PEG-12 is a colorless and tasteless liquid at room temperature.
PEG-12 is readily soluble in water, ethanol, acetone, glycols and chloroform and insoluble in ether, paraffin, oils and fats.
Any of several condensa-tion polymers of PEG-12 with thegeneral formula HOCH2(CH2OCH2)nCH2OH orH(OCH2CH2)nOH.

CAS: 25322-68-3
MF: N/A
EINECS: 500-038-2

PEG-12 Chemical Properties
Melting point: 64-66 °C
Boiling point: >250°C
Density: 1.27 g/mL at 25 °C
Vapor density: >1 (vs air)
Vapor pressure: Refractive index: n20/D 1.469
Fp: 270 °C
Storage temp.: 2-8°C
Solubility H2O: 50 mg/mL, clear, colorless
Form: waxy solid
Color: White to very pale yellow
Specific Gravity: 1.128
PH: 5.5-7.0 (25℃, 50mg/mL in H2O)
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
λmax: λ: 260 nm Amax: 0.6
λ: 280 nm Amax: 0.3
Merck: 14,7568
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: -0.698 at 25℃
NIST Chemistry Reference: PEG-12 (25322-68-3)
EPA Substance Registry System: PEG-12 (25322-68-3)

Uses
Chemical uses
Because PEG-12 is a hydrophilic molecule, it has been used to passivate microscope glass slides for avoiding non-specific sticking of proteins in single-molecule fluorescence studies.
PEG-12 has a low toxicity and is used in a variety of products.
The polymer is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments.
Since PEG-12 is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures (on the order of tens of atmospheres).

PEG-12 also is unlikely to have specific interactions with biological chemicals.
These properties make PEG-12 one of the most useful molecules for applying osmotic pressure in biochemistry and biomembranes experiments, in particular when using the osmotic stress technique.
PEG-12 is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers.
PEG-12 is frequently used to preserve waterlogged wood and other organic artifacts that have been salvaged from underwater archaeological contexts, as was the case with the warship Vasa in Stockholm, and similar cases.

PEG-12 replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.
In addition, PEG-12 is used when working with green wood as a stabilizer, and to prevent shrinkage.
PEG-12 has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China.
These painted artifacts were created during the Qin Shi Huang (first emperor of China) era.
Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xi'an air.
The paint would subsequently flake off in about four minutes.

The German Bavarian State Conservation Office developed a PEG-12 preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.
PEG-12 is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning.
PEG-12 derivatives, such as narrow range ethoxylates, are used as surfactants.
PEG-12 has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.
PEG-12 is a component of the propellent used in UGM-133M Trident II Missiles, in service with the United States Navy.

Industrial uses
A nitrate ester-plasticized PEG-12 is used in Trident II submarine-launched ballistic missile solid rocket fuel.
Dimethyl ethers of PEG-12 are the key ingredient of Selexol, a solvent used by coal-burning, integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the syngas stream.
PEG-12 has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.
PEG-12 is also used as a polymer host for solid polymer electrolytes.

Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving PEG-12, with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future.
PEG-12 is injected into industrial processes to reduce foaming in separation equipment.
PEG-12 is used as a binder in the preparation of technical ceramics.
PEG-12 was used as an additive to silver halide photographic emulsions.

Pharmaceutical Applications
PEG-12 is widely used in a variety of pharmaceutical formulations, including parenteral, topical, ophthalmic, oral, and rectal preparations.
PEG-12 has been used experimentally in biodegradable polymeric matrices used in controlled-release systems.
PEG-12 is stable, hydrophilic substances that are essentially nonirritant to the skin;They do not readily penetrate the skin, although the polyethylene glycols are water-soluble and are easily removed from the skin by washing, making them useful as ointment bases.

Solid grades are generally employed in topical ointments, with the consistency of the base being adjusted by the addition of liquid grades of PEG-12.
Mixtures of PEG-12 can be used as suppository bases,for which they have many advantages over fats.
For example, the melting point of the suppository can be made higher to withstand exposure to warmer climates; release of the drug is not dependent upon melting point; the physical stability on storage is better; and suppositories are readily miscible with rectal fluids.

PEG-12 have the following disadvantages: they are chemically more reactive than fats; greater care is needed in processing to avoid inelegant contraction holes in the suppositories; the rate of release of water-soluble medications decreases with the increasing molecular weight of the PEG-12; and polyethylene glycols tend to be more irritating to mucous membranes than fats.

Aqueous PEG-12 solutions can be used either as suspending agents or to adjust the viscosity and consistency of other suspending vehicles.
When used in conjunction with other emulsifiers, PEG-12 can act as emulsion stabilizers.
Liquid PEG-12 is used as water-miscible solvents for the contents of soft gelatin capsules.
However, they may cause hardening of the capsule shell by preferential absorption of moisture from gelatin in the shell.
In concentrations up to approximately 30% v/v, PEG 300 and PEG 400 have been used as the vehicle for parenteral dosage forms.

In solid-dosage formulations, higher-molecular-weight PEG-12 can enhance the effectiveness of tablet binders and impart plasticity to granules.
However, they have only limited binding action when used alone, and can prolong disintegration if present in concentrations greater than 5% w/w.
When used for thermoplastic granulations,a mixture of the powdered constituents with 10–15% w/w PEG-12 is heated to 70–75°C.
The mass becomes pastelike and forms granules if stirred while cooling.
This technique is useful for the preparation of dosage forms such as lozenges when prolonged disintegration is required.

PEG-12 can also be used to enhance the aqueous solubility or dissolution characteristics of poorly soluble compounds by making solid dispersions with an appropriate polyethylene glycol.
Animal studies have also been performed using PEG-12 as solvents for steroids in osmotic pumps.
In film coatings, solid grades of PEG-12 can be used alone for the film-coating of tablets or can be useful as hydrophilic polishing materials.
Solid grades are also widely used as plasticizers in conjunction with film-forming polymers.

The presence of PEG-12 in film coats, especially of liquid grades, tends to increase their water permeability and may reduce protection against low pH in enteric-coating films.
PEG-12 is useful as plasticizers in microencapsulated products to avoid rupture of the coating film when the microcapsules are compressed into tablets.
PEG-12 grades with molecular weights of 6000 and above can be used as lubricants, particularly for soluble tablets.
The lubricant action is not as good as that of magnesium stearate, and stickiness may develop if the material becomes too warm during compression.

An antiadherent effect is also exerted, again subject to the avoidance of overheating.
PEG-12 have been used in the preparation of urethane hydrogels, which are used as controlled-release agents.
PEG-12 has also been used in insulin-loaded microparticles for the oral delivery of insulin;it has been used in inhalation preparations to improve aerosolization;polyethylene glycol nanoparticles have been used to improve the oral bioavailability of cyclosporine;it has been used in self-assembled polymeric nanoparticles as a drug carrier;and copolymer networks of PEG-12 grafted with poly(methacrylic acid) have been used as bioadhesive controlled drug delivery formulations.

Production
The production of PEG-12 was first reported in 1859.
Both A. V. Lourenço and Charles Adolphe Wurtz independently isolated products that were polyethylene glycols.
PEG-12 is produced by the interaction of ethylene oxide with water, ethylene glycol, or ethylene glycol oligomers.
The reaction is catalyzed by acidic or basic catalysts.
Ethylene glycol and PEG-12's oligomers are preferable as a starting material instead of water, because they allow the creation of polymers with a low polydispersity (narrow molecular weight distribution).
Polymer chain length depends on the ratio of reactants.

HOCH2CH2OH + n(CH2CH2O) → HO(CH2CH2O)n+1H
Depending on the catalyst type, the mechanism of polymerization can be cationic or anionic.
The anionic mechanism is preferable because PEG-12 allows one to obtain PEG with a low polydispersity.
Polymerization of ethylene oxide is an exothermic process.
Overheating or contaminating ethylene oxide with catalysts such as alkalis or metal oxides can lead to runaway polymerization, which can end in an explosion after a few hours.

Polyethylene oxide, or high-molecular-weight polyethylene glycol, is synthesized by suspension polymerization.
PEG-12 is necessary to hold the growing polymer chain in solution in the course of the polycondensation process.
The reaction is catalyzed by magnesium-, aluminium-, or calcium-organoelement compounds.
To prevent coagulation of polymer chains from solution, chelating additives such as dimethylglyoxime are used.
Alkaline catalysts such as sodium hydroxide (NaOH), potassium hydroxide (KOH), or sodium carbonate (Na2CO3) are used to prepare low-molecular-weight polyethylene glycol.

Synonyms
Polyethylene Glycol 600
PEG 600
NL4J9F21N9
CARBOWAX PEG 600
JEECHEM 600
LIPO POLYGLYCOL 600
LIPOXOL 600 MED
MACROGOL 600 DISTEARATE
NORFOX E-600
PEG-12
PLURACARE E 600
POLYETHYLENE GLYCOL 600 (II)
POLYETHYLENE GLYCOL 600 (USP-RS)
POLYGLYKOL 600
SABOPEG 600
TOHO PEG NO. 600
UNIPEG-600
UPIWAX 600

PEG-12 DIMETHICONE = DIMETHYLSILOXANE, ETHYLENE OXIDE BLOCK COPOLYMER


CAS Number: 68937-54-2
EC Number: 614-822-8
MDL Number:MFCD00240065
Chem/IUPAC Name: Dimethyl siloxanes and silicones, 3‐Hydroxypropyl methyl, ethoxylated
Common Name: Ethylene Oxide Dimethicone Copolymer
Molecular Formula: C6H18OSi2


PEG-12 Dimethicone is a type of silicone.
PEG-12 Dimethicone is most often found as ingredient number 12 within an ingredient list.
PEG-12 Dimethicone is a polysiloxane glycol copolymer soluble in water, alcohol and water-alcohol systems.
PEG-12 Dimethicone is a modified polysiloxane having excellent cosmetic worthy properties with uses in personal care industry.


PEG-12 Dimethicone is soluble in water, alcohol, and hydro-alcoholic systems.
PEG-12 Dimethicone is an amphiphilic molecula : the PEG-12 part is hydrophilic, and the Dimethicone part is lipophilic.
And as amphiphilic molecula, Peg-12 Dimethicone has surface active properties : PEG-12 Dimethicone has a HLB value of 14.
PEG-12 Dimethicone is a water soluble polyether modified polysiloxane used as emollient for personal care.


PEG-12 Dimethicone is a synthetic polymer composed of PEG ( polyethylene glycol ) and Dimethicone , a silicon-based polymer.
PEG-12 Dimethicone market exhibits comprehensive information that is a valuable source of insightful data for business strategists during the decade 2019-2029.
On the basis of historical data, PEG-12 Dimethicone market report provides key segments and their sub-segments, revenue and demand & supply data.


Considering technological breakthroughs of the market PEG-12 Dimethicone industry is likely to appear as a commendable platform for emerging PEG-12 Dimethicone market investors.
PEG-12 Dimethicone is a silicone blend of dimethicone and polyethylene glycol.
PEG-12 Dimethicone is a PEG binded with Dimethicone, a silicone-based polymer used to give formulas a smooth feel, promote spreadability, and add lubrication.


PEG-12 Dimethicone is a silicone-based polymer that is combined with polyethylene glycol.
PEG-12 Dimethicone is a low molecular weight compound absorbed minimally into the skin.
PEG-12 Dimethicone is a water-soluble, polyether-modified polysiloxane.
PEG-12 Dimethicone is a PEG binded with Dimethicone, a silicone-based polymer used to give formulas a smooth feel, promote spreadability, and add lubrication.


PEG-12 Dimethicone is blend of skin-protective dimethicone + a lightweight polyethylene glycol
PEG-12 Dimethicone is functions as a hair/skin-conditioning agent
PEG-12 dimethicone is a silicone blend of skin-protective dimethicone and a lightweight polyethylene glycol.
In its raw material form, Peg-12 Dimethicone comes as a clear liquid that ranges from colourless to yellow in appearance.


PEG-12 Dimethicone is a polyether silicone copolymer, the HLB value is 12.
PEG-12 Dimethicone is a polyether silicone copolymer, soluble in water, ethanol and alcohol-water system.
PEG-12 Dimethicone is stable in a water-based systems, and can be added to the hot mixture (up to 90 ºC).
PEG-12 Dimethicone is compatible with water, ethanol (70%), octadecanol, IPM, and stearic acid.


PEG-12 Dimethicone is incompatible or part incompatible with beeswax, glycerin, lanoline, mineral oil, paraffin oil,methyl silicone oil.
PEG‐12 Dimethicone is a silicone glycol copolymer soluble in water, alcohol, and hydro‐alcoholic systems.
PEG-12 Dimethicone, a polyether silicone, is a safe water-soluble surfactant at normal usage, with good moisturizing, foam-stabilizing and conditioning capacity.


A type that can be directly distributed in water because Peg-12 Dimethicone has been emulsified or has changed its structure to be able to dissolve in water.
PEG-12 Dimethicone is also an emulsifier, used to stabilize or homogenize its texture.
PEG-12 Dimethicone is an ethoxylated polydimethylsiloxane that is soluble in water.


In colder temperature PEG-12 Dimethicone may freeze up and become solid and in hotter temperatures it will be liquid.
PEG-12 Dimethicone is a blend of skin-protective dimethicone and lightweight polyethylene glycol and is soluble in water, alcohol, and hydro-alcoholic systems.
Peg-12 Dimethicone is a fluid silicone that reduces surface tension.


PEG-12 Dimethicone is stable in neutral, mildly acidic or alkaline aqueous solutions.
PEG-12 Dimethicone's stability is reduced by strong acid or alkali.
PEG-12 Dimethicone can improve oil (or silicone) in water emulsions with faster absorption, better spreading, and a lighter feel.
PEG-12 dimethicone is a silicone blend of skin-protective dimethicone and a lightweight polyethylene glycol.


In its raw material form, PEG-12 dimethicone comes as a clear liquid that ranges from colorless to yellow in appearance.
In a 2015 report, the Cosmetic Ingredient Review Expert Panel deemed PEG-12 dimethicone as safe in cosmetic use.
PEG-12 Dimethicone is a silicone glycol copolymer that is soluble in water, alcohol, and hydro-alcoholic systems.
PEG-12 Dimethicone is both water and alcohol compatible.


PEG-12 Dimethicone is a moisturizing and conditioning silicone.
PEG-12 Dimethicone is a water-, alcohol-, and alcohol-water-soluble silicone-glycol copolymer with high hydrolytic stability.
"PEG" refers to a PEG (polyethylene glycol) derivative.
The number after "PEG-" (or the first number after "PEG/...-") indicates the average number of molecular units -CH2-CH2-O-.


PEG-12 Dimethicone is ingredient based on poly(di)methylsiloxane ("Dimethicone").
PEG-12 Dimethicone is a fluid silicone that reduces surface tension.
PEG-12 Dimethicone can improve oil (or silicone) in water emulsions with faster absorption, better spreading, and a lighter feel.


PEG 12 Dimethicone is a PEG binded with Dimethicone, a silicone-based polymer used to give formulas a smooth feel, promote spreadability, and add lubrication.
PEG 12 Dimethicone is a polyether compound with many applications, from industrial manufacturing to medicine.
PEG-12 Dimethicone is a silicone glycol copolymer soluble in water, alcohol, and hydro-alcoholic systems.



USES and APPLICATIONS of PEG-12 DIMETHICONE:
PEG-12 simethicone is also used in a variety of cosmetics and personal care products, including hair sprays, shampoos, skin care, lotions, perfumes and shaving soaps, and can also generate and maintain stable foam.
In the formula of conditioner and shampoo, PEG-12 Dimethicone can give the hair a silky soft feeling even after repeated washing without accumulation.


In addition, PEG-12 Dimethicone has conditioning, emollient and detackifying effects in body and hair shower products.
PEG-12 Dimethicone can be used as a surface tension inhibitor, wetting agent, emulsifier and foaming aid to produce and maintain foam in high-alcohol hand sanitizer formulations.
PEG-12 Dimethicone acts as a surface tension depressant, wetting agent, emulsifier and foam builder in a wide variety of cosmetic and personal care products, including hair sprays, shampoos, skin care, lotions, perfumes and shaving soaps.


PEG-12 Dimethicone provides the properties of conditioning, emolliency and de-tackification in both body and hair shower products.
PEG-12 Dimethicone is used for Temporarily protecting and relieving chapped or chapped skin, Deodorant, Hairspray and other conditions.
PEG-12 Dimethicone is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
PEG-12 Dimethicone is used temporarily protecting and relieving chapped or cracked skin, Deodorant, and Hair spray


PEG-12 Dimethicone is soluble in water.
In cosmetics, this silicone works as an emollient.
PEG-12 Dimethicone reduces the surface tension and cohesion of other substances.
PEG-12 Dimethicone promotes good spreadability of the product.


PEG-12 Dimethicone leaves a smooth feeling on the hair and skin.
In addition Peg-12 Dimethicone may be used as foam booster, emulsifier, plasticizing agent and wetting agent for personal care products.
PEG-12 Dimethicone acts as a surface tension depressant, hair conditioning agent, skin conditioning agent, wetting agent, emulsifier and foam builder in a wide variety of beauty products and cosmetics.


PEG-12 Dimethicone is used as an emulsifier, light conditioner, skin emollient, and has a wide range of applications in personal care products including hand sanitizers, leave-in hair products, shampoos, skin care lotions & shaving soaps.
PEG-12 Dimethicone also helps improve the texture and perceived finish of skin care formulas.
PEG-12 Dimethicone deemed a safe cosmetic ingredient.


PEG-12 Dimethicone functions as a hair/skin-conditioning agent.
PEG-12 Dimethicone can also help improve the overall texture and finish of skin care formulas.
PEG-12 Dimethicone can be used in shampoo, body emulsion, shaving cream, hairspray and other disposable hair care products.
PEG-12 Dimethicone acts as a surface tension depressant, wetting agent, emulsifier and foam builder to create and sustain foam in a high alcohol‐content hand sanitizer formulations.


PEG‐12 Dimethicone is also used in in a wide variety of cosmetic and personal care products, including, hair sprays, shampoos, skin care, lotions, perfumes and shaving soaps to create a stable foam.
In conditioner and shampoo formulations, PEG‐12 Dimethicone imparts a silky, soft feel to the hair without build up even after repeated wash cycles.


Further, PEG‐12 Dimethicone provides conditioning, emolliency and detackification in both body and hair shower products.
PEG‐12 Dimethicone is widely used as an inactive ingredient in alcohol‐based hand sanitizers to form a dense, stable foam
PEG-12 Dimethicone is used as surfactant and hair conditioner. As surfactant it works to build a dense and stable foam and to decrease surface tension of liquids.


As hair conditioner Peg-12 Dimethicone helps to enhance the appearance and feel of hair, increase suppleness, improve gloss or sheen and improve the texture of hair.
PEG-12 Dimethicone is mainly used as a skin and hair conditioning agent.
PEG-12 Dimethicone can be used as an emollient, foam booster, emulsifier, plasticizing agent and wetting agent in personal care formulations.


PEG-12 Dimethicone acts as a surface tension depressant, hair conditioning agent, skin conditioning agent, wetting agent, emulsifier and foam builder in a wide variety of beauty products and cosmetics.
Because of PEG-12 Dimethicone's low molecular weight, it is minimally absorbed by the skin.
PEG-12 Dimethicone can be used as hair conditioner to provide hair a silky feel, also used as skin emollient, widely applied in 2 in 1 shampoo, styling product, soap, shaving product, skin lotion, make-up foundation and antiperspirant.


PEG-12 Dimethicone is clear liquid silicone that can be mixed with water directly without the use of other substances in the coordination.
PEG-12 Dimethicone is suitable for mixing in shampoo formulas. (conditioning shampoo) to make hair soft and smooth and prevent hair tangling.
PEG-12 Dimethicone can be used in any skin cream formula help act as skin-conditioning Makes the skin soft and smooth.
PEG-12 Dimethicone is suitable for use in shampoo, conditioner and hair treatment formulas which can be added to the water in the formula at all.


PEG-12 Dimethicone is a copolymer of polydimethysiloxane and polyoxyalkaylene ether, PEG-12 Dimethicone is an O/W emulsifier which imparts lubricity and softness to personal care formulations.
Due to its water solubility PEG-12 Dimethicone can be used to formulate clear products.
When used in shampoo formulations PEG-12 Dimethicone exhibits profoaming qualities helping to stabilise foam levels.


In styling products, PEG-12 Dimethicone acts as a plasticiser.
PEG-12 Dimethicone is used anti-perspirant roll-ons, hair sprays, conditioners, hand lotion, conditioning shampoos, mousses, foundation, shampoos, gel/setting lotions, shaving preparation.
PEG-12 - is an emulsifier, light conditioner, skin emollient, and has a wide range of applications in personal care products including hand sanitizers (providing moisturizing, emolliency and lubricating properties), leave-in hair products, shampoos, skin care lotions & shaving soaps.


PEG-12 Dimethicone imparts a soft silky feel to the hair and functions as a humectant and emollient in skin care products.
PEG-12 Dimethicone forms dense stable foam in aqueous products and is an effective wetting agent and emulsifier.
PEG-12-Dimethicone is a water- soluble copolymer with conditioning effect, a mixture of polydimethylsiloxane and polyethylene/polypropylene-oxide.
PEG-12 Dimethicone provides a rich lather in hair mousses.


PEG-12 Dimethicone functions as a hair/skin-conditioning agent.
PEG-12 Dimethicone also helps improve the texture and perceived finish of skin care formulas.
PEG-12 Dimethicone deemed a safe cosmetic ingredient.
PEG-12 Dimethicone functions as a hair/skin-conditioning agent.


PEG-12 Dimethicone can also help improve the overall texture and finish of skin care formulas.
PEG-12 Dimethicone acts as an emollient in hand sanitizing gels/foams to prevent chapping of hands from the alcohol.
Recommended usage of PEG-12 Dimethicone is in alcohol based hand and general sanitizer gels is 0.1-0.3%.
PEG-12 Dimethicone acts as a surface tension depressant, wetting agent, emulsifier and foam builder to create and sustain foam in a high alcohol-content hand sanitizer formulations.


PEG-12 Dimethicone is a silicone polyether co-polymer surfactant used extensively in hair care products, skin care products and shaving lotions.
PEG-12 Dimethicone can form stable foam at low dosages while also giving a soft feel to skin.
PEG-12 Dimethicone is used shampoo, conditioner, hair styling, lotion, cream, sunscreen, cosmetics, emulsions, etc.
PEG-12 Dimethicone is a safe water soluble surfactant under normal use with good wetting, foaming and conditioning properties.


PEG-12 Dimethicone combines well with other ingredients and works at a low dosage.
PEG-12 Dimethicone can be used as a hair conditioner to make hair silky, also used as a skin emollient, widely used in 2 in 1 shampoo, styling product, soap, shaving cream, skin lotion, makeup base and antiperspirant.
PEG-12 Dimethicone is used in the cosmetic industry as a moisturizing agent, emulsifier, including for clear emulsions.


PEG-12 Dimethicone is used in skin care, hair care, shaving products, antiperspirants.
White emulsions, gel-cream, translucent emulsions and clear (water-based) systems.
PEG-12 Dimethicone can be used as hair conditioner to provide hair a silky feel, also used as skin emollient, widely applied in 2 in 1 shampoo, styling product, soap, shaving product, skin lotion, make-up foundation and antiperspirant.


PEG-12 Dimethicone can be used as hair conditioner to provide hair a silky feel, also used as skin emollient, widely applied in 2 in 1 shampoo, styling product, soap, shaving product, skin lotion, make-up foundation and antiperspirant
PEG-12 Dimethicone acts as a surface tension depressant, wetting agent, emulsifier and foam builder in a wide variety of cosmetic and personal care products, including hair sprays, shampoos, skin care, lotions, perfumes and shaving soaps.


PEG-12 Dimethicone is widely used in Cream, Lotions, Gels, Shampoo, and Conditioners.
PEG-12 Dimethicone acts as a surface tension depressant, hair conditioning agent, skin conditioning agent, wetting agent, emulsifier and foam builder in a wide variety of beauty products and cosmetics.
Because of PEG-12 Dimethicone's low molecular weight, it is minimally absorbed by the skin.


-DIY PERSONAL CARE:
Peg-12 Dimethicone is used in combination with other products to make cosmetics, make up, beauty and personal care products.


-MULTI USE of PEG-12 Dimethicone:
Cosmetic Grade Peg-12 Dimethicone is used as a raw material for your cosmetic brand or DIY use to make products such as facial mask, face and body scrubs, lotions, creams, moisturizers, serums, body butters, hair and skin care and bath products, pressed powders, liquid foundation, mascara, deodorant soap, shampoo making and many more beauty and make up products


-Applications of Peg-12 Dimethicone:
*2 in 1 shampoo
*Styling product
*Body wash, soap, shaving product and facial cleanser
*Skin lotion, make-up foundation and antiperspirant product


-Hand & Body Care uses of PEG-12 Dimethicone:
*Hair gel
*Hair foam
*Hair conditioner
*Wax


-Silicone Family:
Peg-12 Dimethicone provides the unique softness of silicones that are silky smooth over any substitutes.


Applications of PEG-12 Dimethicone:
• Automotive and household cleaning.
• Shampoos and Conditioners
• Textile.
• Skin lotions


-Uses of PEG-12 Dimethicone:
*Hair spray
*Shampoo
*Pre‐shave lotion
*Shaving cream
*Skin lotions
*Perfumes


-Usage of PEG-12 Dimethicone:
*Cosmetic Raw Materials,
*Hair Care Chemicals


-Cosmetic effect of PEG-12 Dimethicone:
Peg-12 Dimethicone is emollient.
When used in skin and hair care products, Peg-12 Dimethicone creates an occlusive layer on their surface, which prevents excessive evaporation of water (this is an indirect moisturizing effect), thus conditioning the skin and hair, i.e. smoothing and softening.
Peg-12 Dimethicone is non-comedogenic substance - does not cause blackheads.


-Usage of PEG-12 Dimethicone:
*Hair Products
*Cosmetic products
*Colour Cosmetics
*Personal Care
*Lotion
*Conditioner
*Cream
*Sunscreen


-Peg-12 Dimethicone is suitable for a wide range of applications in personal care products including:
▶ Bath and shower products.
▶ Hair treatments and hair styling products.
▶ Shampoos and rinse-off conditioners.
▶ Skin care products – facial and body care products, make-up removers.
▶ Color cosmetics – foundations, BB creams.
▶ Shaving foams and gels


-Skin care:
Peg-12 Dimethicone functions as a humectant and emollient in skin care products.
Peg-12 Dimethicone is used in moisturizer, around-eye cream, serums & essences, hand cream, toner, astringent, facial moisturizer/treatment, body wash/cleanse


-Hair care:
Peg-12 Dimethicone imparts a soft silky feel to the hair and is used in various hair care products such as hair treatment/serum, hair spray, hair styling aide, shampoo, shaving cream, hair color and bleaching, styling mousse/foam, styling gel, conditioner, mask


-Decorative cosmetics:
Peg-12 Dimethicone is used in cosmetics such as lipstick, concealer, eye shadow, foundation, CC cream, blush, lip balm, facial powder, bronzer/highlighter, lip gloss, BB cream, makeup primer, brow liner, lip liner, eye liner, lip plumper, lip balm, makeup remover



FEATURES OF PEG-12 DIMETHICONE:
*Surface Tension reducer
*Excellent conditioner
*Foam builder
*Solubility in water
*Light conditioning effect
*Surface tension reduction
*Good wetting properties
*Soft, silky feel to hair and skin
*Forms a stable foam
*Low surface tension and good wetting agent
*Compatible with most formulations and cosmetic ingredients
*Excellent plasticizing agent and humectant
*Forms dense/stable foam in the hand sanitizer formulation
*Low dosage required to achieve stable foam
*Compatible with water and alcohol
*Surface tension inhibitor
*Gives a soft silky feel to the hair care formula.
*Effective surface tension depressant
*Excellent conditioning
*Imparts a silky soft feel
*Detackifies greasy formulations
*Good foam builder
*Low usage levels required
*Compatible with a wide range of cosmetic ingredients
*Ensures smooth wet shaving foams
*In Skincare products, it is mainly used as emollient and lubricant.
*O/W emulsifier, an ingredient that enables the formation of an emulsion.
*Emulsion is a physicochemical form that is created by combining (mixing) the water phase with the oil phase.
*Examples of cosmetic emulsions are creams, lotions, balms.
*Silicones give a silky effect on the skin.
*Forms a dense/stable foam in hand sanitizer formulations
*Low usage levels required to attain a stable foam
*Water & alcohol compatible
*Surface tension depressant
*Imparts a soft silky feel in hair care formulations
*Readily soluble and stable in cool water and lower alcohols
*Exhibits surfactant-like qualities
*Profoaming
*Acts as a hydrator and detackifier



BENEFITS OF PEG-12 DIMETHICONE:
*Improves foam
*Enhances silky skin feel
*Improves wet and dry combing
*Provides lubricity to hair and skin
*Pro-foaming
*Humectant
*Wet conditioner
*Provide silicone properties to clear, aqueous based formulation
*Low usage levels required to attain a stable foam
*Water & alcohol compatible
*Surface tension depressant
*Imparts a soft silky feel in hair care formulations



KEY BENEFITS OF PEG-12 DIMETHICONE:
▶ Improves foam of bath products.
▶ Enhances silky skin feel.
▶ Light conditioning effect improving wet&dry combing.
▶ Emulsifier for fragrances and essential oils or pigments.
▶ Second surfactant for sensitive product.
▶ Provides surface tension reduction.
▶ Provides lubricity to hair and skin.



FUNCTIONS OF PEG-12 DIMETHICONE:
Emollient, Thickener, Emulsifier, Conditioner, Surfactant (Nonionic), Plasticizer, Wetting Agent, Adhesion Promoter, Foaming Agent, Cleansing Agent, Viscosity Modifier, Foam Booster, Re-Fatting Agent, Surfactant
Humectant, wet conditioner, emollient, soft and silky skin feel.
Anti-foaming Agent / Defoamer - Reduces or hinders the formation of foam.
PEG-12 Dimethicone is a PEG binded with Dimethicone, a silicone-based polymer used to give formulas a smooth feel, promote spreadability, and add lubrication.
Peg-12 Dimethicone acts as a surface tension depressant, hair conditioning agent, skin conditioning agent, wetting agent, emulsifier and foam builder in a wide variety of beauty products and cosmetics.
Because of PEG 12 Dimethicone's low molecular weight, it is minimally absorbed by the skin.
Hair conditioner: Leaves hair easy to comb, supple, soft and shiny and/or gives volume, lightness and shine
Skin conditioning agent: Keeps the skin in good condition



ADVANTAGES OF PEG-12 DIMETHICONE:
1. Small dosage
2. To be a humectant and emollient for personal care
3. To make the hair more slippery and softer
4. Be compatible with various personal care products ingredients.
5. Emulsifier
6. Hair styling products resin plasticizer
7. Wetting agent



PROPERTIES OF PEG-12 DIMETHICONE:
*Excellent conditioning ability, provide a silky feeling
*Function with little dosage
*Good compatibility with other ingredients
*No irritation to skin
*Good foam stability and lubricative effect.
*Reduces surface tension, improves foaming
*Excellent air conditioning
*Gives silky softness to skin and hair
*Stable foam structure
*Low % input
*Compatible with a wide range of cosmetic ingredients
*Provides soft lather for a wet shave
*Acts as a hydrator and de-tackifier



WHAT DOES PEG-12 DIMETHICONE DO IN A FORMULATION?
*Emollient
*Hair conditioning
*Skin conditioning



PEG-12 DIMETHICONE ALTERNATIVES:
*COCOCAPRYLATE CAPRATE



FORMULAS THAT PEG-12 DIMETHICONE IS USED:
*After Sun- Gel
*Antiperspirant Gel
*Car Tire Cleaning Polishing
*Dual Phase Blow Dry (Late Decomposition)Jelly-High grip
*Manicure, Pedicure Solution
*Hair gel
*Hair Gel - Biryantin
*Hair Gel - Hard
*Hair Gel- Air Bubble & Hard
*Hair Foam Aerosol - NEW
*Hair Spray - Pump - Ultra Hard
*Hair Spray - Hard
*Hair Spray Ultra
*Hair Spray - Thermal Resistant - Pumpable
*Hair Wax-Pearlizing Putty
*Shaving Gel - No More Irritation
*Shaving cream
*Shaving Cream - Refreshing
*All Day Makeup Setting Spray



PHYSICAL and CHEMICAL PROPERTIES of PEG-12 DIMETHICONE:
Boiling Point: >35°C
Solubility: Soluble in water, ethanol and alcohol-water system
Viscosity: 200-1000 cps
Appearance: transparent to turbid liquid
Color(Gardner): 0-4
Viscosity (25ºC): 200-500cs
Surface tension: 28±2mN/m(1% water solution)
Cloud point: 95-100ºC
Refractive index(25ºC): 1.4500-1.4600
Density(25ºC): 1.070-1.080

Appearance:Clear to hazy liquid, light amber color
Appearance: Colorless or light yellow transparent liquid.
Viscosity: @ 25°C 260cSt
Specific Gravity: 1.07
Cloud Point: 95°C to 100°C
Color (Gardner scale): 0 to 4
Melting point:−14 °C
Boiling point:>250°C
Density: 1.035 g/mL at 25 °C
refractive index: n20/D 1.455
Flash point: >230 °F
Specific Gravity: 1.09


Melting point: −14 °C
Boiling point: >250°C
Density: 1.035 g/mL at 25 °C
refractive index: n20/D 1.455
Flash point: >230 °F
Specific Gravity: 1.09
Physical state: liquid
Color: amber
Odor: characteristic
Odor Threshold: No data available
pH: No data available
Melting point/range: No data available
Freezing point: No data available

Boiling point (760 mmHg): > 35 °C ( > 95 °F)
Flash point: 113 °C ( 235 °F)
Evaporation Rate (Butyl Acetate= 1): No data available
Flammability (solid, gas): Not applicable
Lower explosion limit: No data available
Upper explosion limit: No data available
Vapor Pressure: No data available
Relative Vapor Density (air = 1): No data available
Relative Density (water = 1): 1.07
Water solubility: No data available
Partition coefficient: noctanol/water: No data available

Auto‐ignition temperature: No data available
Decomposition temperature: No data available
Kinematic Viscosity: 260 mm2/s at 25 °C (77 °F)
Explosive properties: Not explosive
Oxidizing properties: The substance or mixture is not classified as oxidizing.
Molecular weight: No data available
Particle size: Not applicable
Surface tension: 28.86 dyn/cm 1024 F
Appearance: Clear liquid

Color: Colorless to yellow
Viscosity, at 25°C, mPa.s: 200 to 800
Specific gravity at 25°C, g/cm3, approx.: 1.080
Refractive Index, 25°C, approx.: 1.457
HLB (calculated), approx.: 14
Flash point (closed cup), °C: > 100
Cloud point (4% in distilled water), °C, approx.: 90
Dry content, %: > 97
D4 content, %.: < 0.1



FIRST AID MEASURES of PEG-12 DIMETHICONE:
-Description of first aid measures
*General advice:
*Inhalation:
Move person to fresh air; if effects occur, consult a physician.
*Skin contact:
Wash off with plenty of water.
*Eye contact:
Flush eyes thoroughly with water for several minutes.
Remove contact lenses after the initial 1‐2 minutes and continue flushing for several additional minutes.
If effects occur, consult a physician, preferably an ophthalmologist.
Suitable emergency eye wash facility should be available in work area.
*Ingestion:
No emergency medical treatment necessary.



ACCIDENTAL RELEASE MEASURES of PEG-12 DIMETHICONE:
-Personal precautions, protective equipment and emergency procedures:
Follow safe handling advice and personal protective equipment recommendations.
-Methods and materials for containment and cleaning up:
Soak up with inert absorbent material.
Clean up remaining materials from spill with suitable absorbent.



FIRE FIGHTING MEASURES of PEG-12 DIMETHICONE:
*Suitable extinguishing media:
Water spray
Alcohol‐resistant foam
Carbon dioxide (CO2)
Dry
*Unsuitable extinguishing media:
None known.



EXPOSURE CONTROLS/PERSONAL PROTECTION of PEG-12 DIMETHICONE:
-Individual protection measures:
*Eye/face protection:
Use safety glasses (with side shields).



HANDLING and STORAGE of PEG-12 DIMETHICONE:
-Precautions for safe handling:
Handle in accordance with good industrial hygiene and safety practice.
-Conditions for safe storage:
Keep in properly labelled containers.
Store in original container.
Store in accordance with the particular national regulations.
-Unsuitable materials for containers:
None known.



STABILITY and REACTIVITY of PEG-12 DIMETHICONE:
-Reactivity:
Not classified as a reactivity hazard.
-Chemical stability:
Stable under normal conditions.
-Conditions to avoid:
None known.



SYNONYMS:
Dimethylsiloxane, Ethylene Oxide Block Copolymer
Ethoxylated 3-Hydroxypropyl Methyl Dimethyl Siloxanes and Silicones
PEG-12 Dimethicone (INCI)
Polyethylene Glycol (12) Dimethicone
Polyoxyethylene (12) Dimethicone
Siloxanes and Silicones, Di-Me, 3-Hydroxypropyl Me, Ethoxylated
PEG-12 DIMETHICONE;DC 5329 Perform Modifier
POLY(DIMETHYLSILOXANE-B-ETHYLENE OXIDE), METHYL TERMINATED
POLY[DIMETHYLSILOXANE-CO-METHYL(3-HYDROXYPROPYL)SILOXANE]-GRAFT-POLY(ETHYLENE GLYCOL) METHYL ETHER
POLY(DIMETHYLSILOXANE-CO-ETHYLENE OXIDE), AB BLOCK COPOLYMER
SiloxanesandSilicones,di-Me,3-hydroxypropylMe,ethoxylated
DIMETHYLSILOXANE, ETHYLENE OXIDE BLOCK COPOLYMER
ETHYLENE OXIDE-DIMETHYLSILOXANE-ETHYLENE OXIDE BLOCK POLYMER,HYDROXYL TERMINATED
Ethylene oxide-dimethylsiloxane-ethylene oxide block polymer
PEG-9 DIMETHICONE
PEG-8 DIMETHICONE
PEG-10 DIMETHICONE
PEG-9 DIMETHICONE
X 22-6551
Silicone B
Silsurf D 208
Silwet L 7608
Tegopren 5842
Silwet FZ 2171
Silsurf D 212CG

PEG-120 METHYL GLUCOSE DIOLATE is classified as :Emulsifying PEG-120 METHYL GLUCOSE DIOLATE CAS Number 86893-19-8 PEG-120 METHYL GLUCOSE DIOLATE Chem/IUPAC Name:Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, ether with methyl d-glucopyranoside 2,6-bis[(Z)-9-octadecenoate] (2:1) (120 mol EO average molar ratio) PEG-120 METHYL GLUCOSE DIOLATE APPEARANCE:Yellowish or white waxy solid PEG-120 METHYL GLUCOSE DIOLATE DETAILS:Polyethylene glycol ether of the diester of methyl glucose and oleic acid with an average of 120 moles of ethylene oxide.Surfactant/thickener/solubilizer/emulsifier mainly used in cosmetics and personal care products. PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in Turkish is used for Skin conditioning, Skin conditioning and other conditions. PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in Turkish and detailed information on precautions are as follows: PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in Turkish is used for the treatment, control, prevention & improvement of the following diseases, conditions and symptoms:Skin conditioning. More information: Uses: Side effects. The following is a list of possible side effects that may occur in medicines that contain PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in Turkish. This is not an exhaustive list. These side effects are likely to occur, but do not always occur. Some of the side effects are rare but can be very serious. Be sure to consult your doctor if you observe any of the following side effects, especially those that do not go away although you expect them to. Irritation If you notice any side effects other than those listed below, consult your doctor for medical advice. You can also report side effects to your nearest health department official. Precautions: Please consult your doctor or pharmacist for this information, or refer to the package insert. , skin conditioning and skin conditioning, PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in Turkish are among the most common reported uses of the drug. Please do not use PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in Turkish for skin conditioning and skin conditioning without consulting first with your doctor. Click here and view the survey results to find out what other patients have said about PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in English. Is it safe to drive or use heavy machinery while using this product? If you experience side effects such as dizziness, hypotension (low blood pressure) or headache, it may not be safe for you to drive and / or use a construction machine. If the medication used causes drowsiness, dizziness or lowers your blood pressure, you should not drive. In addition, pharmacists advise patients not to drink alcohol with the drug, as alcohol intensifies side effects such as drowsiness. Please check for these effects on your body when using PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in Turkish. Always consult your doctor for advice specific to your body and health condition. Is this drug or product addictive or addictive? Many drugs are not placed on the market in an addictive or abusive manner. Often, ministries categorize drugs as controlled addicts and non-addictive. For example, this classification is H and X in India and II and V in the USA. Please check the box to make sure the drug belongs to such a special classification. Finally, do not try to self-medicate without a doctor's advice and do not increase your body's dependence. Can I stop using this product immediately or do I gradually get rid of it? Some medicines should be tapered or discontinued to avoid withdrawal effects. Consult your doctor for advice specific to your body, health condition and other medications you can use. Other important information about PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in Turkish. If you forget to take a dose of medication, use it as soon as it does. If your next dose is too close to your time, stop taking the missed dose and stick to your dosing schedule. Do not take extra doses to treat the missed dose. If you regularly forget your doses, set an alarm or ask a family member to remind you. Please consult your doctor to make a change in your dosing schedule or to make up for missed doses if you have recently forgotten too many doses PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in Turkish Do not use more than prescribed dose. Consuming more of the drug will not improve your symptoms; on the contrary, it can cause poisoning or serious side effects. If you suspect that you or a relative has used an overdose of PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in Turkish, please visit the emergency department of the nearest hospital. To help doctors, bring necessary information, such as a medicine box, bottle, or label, if you know they have the same condition or there are similar situations gDo not give your medication to anyone else, even if it looks like it. This can lead to an overdose. For more information, consult your pharmacist or check the package insert. Storage of PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate. Store medicines at room temperature, away from heat and light. Do not freeze medicines unless it is written on the package insert. Keep medicines out of the reach of children and pets. Do not pour medicines into the toilet or sink unless you are instructed to do so in the prospectus. Drugs disposed in this way can pollute the nature. Please consult your doctor or pharmacist on how to safely discard PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in Turkish. Expired PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in Turkish. One dose has expired PEG-120 METHYL Using GLUCOSE DIOLEATE / Methyl Glucose Dioleate in Turkish is likely to cause an adverse event. Consult your family doctor or pharmacist for appropriate advice or if you feel unwell. Expired drugs will not be effective in treating conditions on your prescription. To stay safe, it is very important not to use expired medications. If you have a chronic illness that requires continued medication, such as heart disease, seizures and life-threatening allergies, it is even more important to stay in touch with your GP so that you can replace expired medications immediately. Dosage Information: Please consult your doctor or pharmacist or read the package insert. .PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in Turkish- Uses, Side Effects, Reviews, Precautions - drugs.net. (n.d.). Retrieved June 18, 2020, from https: //www.ilaçlar.net/medicine-tr/peg-120-methyl-glucose-dioleate. "PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in Turkish - Uses, Side Effects, Reviews, Precautions - İlaç.net "Tabletwise.com. N.p., n.d. The web. 18 Jun. 2020. "PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in English - Uses, Side-Effects, Reviews, and Precautions - medicines.net" Tabletwise. Accessed June 18, 2020.https: //www.ilaçlar.net/medicine-tr/peg-120-methyl-glucose-dioleate. PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in skin conditioning treatment PEG-120 in Turkish skin conditioning treatment METHYL GLUCOSE DIOLEATE / Methyl Glucose Dioleate in Turkish.PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate in Turkish.More about Consumer Questionnaire - PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate. Results of ongoing survey for Dioleate on TabletWise.com. These results only show the perceptions of the users of this website. Please make your medical decisions based on the advice of a doctor or a specialist. Uses, Efficiency and Side Effects. The following are information on the use, perceived efficiency and frequency of side effects offered by site visitors for PEG-120 METHYL GLUCOSE DIOLATE / Methyl Glucose Dioleate: Uses: The most common use of this drug is: Skin conditioning.PEG 120 Methyl Glucose Dioleate is the polyethylene glycol ether of the diester of natural Methylglucose and Oleic Acid. It is used in beauty products and cosmetics as a surfactant and emulsifier. It is used as a thickener in hair and skin care products. It is considered a non-irritant, and also has a specific property that allows it to reduce the irritation value of whole formulas (Source). The high molecular weight of this specific PEG makes it impenetratable to healthy skin; it is FDA and CIR approved for use, but not on broken skin.(PEG 120 Methyl Glucoside Dioleate, Methyl Glucoside Dioleate, PEG-20 Methyl Glucose Sesquistearate, Methyl Glucose Sesquistearate, PPG-20 Methyl Glucose Ether, PPG-20 Methyl Glucose Ether Distearate, PPG-10 Methyl Glucose Ether, Methyl Glucose Isostearate, Methyl Gluceth-10, Methyl Gluceth-20, PEG-20 Methyl Glucose Trioleate, PEG-120 Methyl Glucose Trioleate) By Form (Liquid, Powder), By Application, Industry Analysis Report, Country Outlook, Application Potential, Price Trend, Competitive Market Share & Forecast, 2019 - 2025.PEG 120 Methyl Glucoside Dioleate holds a significant share in the overall market. The product functions as a surfactant and emulsifier in skincare and haircare products. It does not cause irritation and is considered to minimize the irritation value of whole formulas. Moreover, Methyl Gluceth-20, a corn-sugar derived active cosmetic ingredient, is projected to grow at a considerable rate over the forecast timeframe. The product offers water-retention characteristics to prevent water-loss from the skin along with emulsifying & thickening properties. It is non-tacky, and finds application in cleansers, creams, hair care, and color cosmetics.PEG-120 distearate (INCI) is a polyethylene glycol derivative used in cosmetic preparations. Distearates are salts or diesters of stearic acid. The number 120 after "PEG-" indicates the average number of molecular units -CH2-CH2-O-. PEG-120 distearate acts as emulsifier.PEG-120 METHYL GLUCOSE DIOLATE is a PEG ether of the diester of methyl glucose and oleic acid with avg. 120 moles of ethylene oxide PEG-120 METHYL GLUCOSE DIOLATE uses and applications include: Thickener, emulsifier, solubilizer for shampoos, cosmetics, topical pharmaceuticals; anti-irritant for surfactants.

PEG-120 Methyl Glucose Dioleate is a liquid, highly efficient viscosity builder designed for use with numerous anionic surfactants and amphoteric surfactant systems popular in many shampoos, body washes, and liquid soaps.
PEG-120 Methyl Glucose Dioleate is methyl glucose ether which has been esterified with oleic acid.
PEG-120 Methyl Glucose Dioleate adds body and provides a rich skin feel to this exceptionally mild, high foaming body wash.

CAS Number: 86893-19-8
Molecular Formula: (C2H4O)n(C2H4O)nC43H78O8

PEG-120 Methyl Glucose Dioleate is a naturally-derived, methyl glucose ether which has been esterified with oleic acid.
PEG-120 Methyl Glucose Dioleate is a flaked solid, highly efficient viscosity builder designed for use with numerous anionic surfactants and amphoteric surfactant systems popular in many shampoos, body washes, and liquid soaps.
PEG-120 Methyl Glucose Dioleate is non-irritating to the eyes, making PEG-120 Methyl Glucose Dioleate ideal for baby shampoos.

PEG-120 Methyl Glucose Dioleate is especially applicable to some surfactants hardly to thicken.
PEG-120 Methyl Glucose Dioleate causes no irritation to eyes, meanwhile significantly reduces irritation of whole formula.

PEG-120 Methyl Glucose Dioleate is a naturally derived grade.
PEG-120 Methyl Glucose Dioleate is methyl glucose ether which has been esterified with oleic acid.
PEG-120 Methyl Glucose Dioleate is mild, non-irritating to the eyes and offers light feel.

PEG-120 Methyl Glucose Dioleate enables formulations that are easy to pour and have aesthetically pleasing foaming properties.
PEG-120 Methyl Glucose Dioleate is used in shampoos, body washes, liquid soaps, baby shampoos, intimate & mild cleansers.

PEG-120 Methyl Glucose Dioleate is also has antibacterial action through incorporation of the active ingredient, triclosan.
The afterfeel is improved due to the conditioning effects of the cationic polymer and PEG-120 Methyl Glucose Dioleate, a mild monomeric quaternary.
PEG-120 Methyl Glucose Dioleate helps build viscosity and improves quality of the foam.

PEG-120 Methyl Glucose Dioleate is a 70% active, naturally-derived, methyl glucose ether which has been esterified with oleic acid.
PEG-120 Methyl Glucose Dioleate is a liquid, highly efficient viscosity builder designed for use with numerous anionic surfactants and amphoteric surfactant systems popular in many shampoos, body washes, and liquid soaps.

PEG-120 Methyl Glucose Dioleate is a vegetable-derived highly efficient viscosity builder designed for use with numerous anionic surfactants and amphoteric surfactant systems popular in many shampoos, body washes and liquid soaps.
PEG-120 Methyl Glucose Dioleate is recommended for clean beauty applications.

PEG-120 Methyl Glucose Dioleate is a plant-derived thickener that can be used with a variety of anionic homo-amphoteric active interface agents.
PEG-120 Methyl Glucose Dioleate is non- irritant to the eyes.
Especially suitable for amino acid anion active interface agent, can make thick shampoo.

PEG-120 Methyl Glucose Dioleate is a naturally derived Methyl Glucoside derivative.
PEG-120 Methyl Glucose Dioleate adds body and provides a rich skin feel to this exceptionally mild, high foaming body wash.
Methyl Glucoside derivatives are well known for their mildness and irritation mitigation properties.

PEG-120 Methyl Glucose Dioleate is a highly efficient viscosity builder of vegetable origin designed for use with numerous anionic surfactants (i.e., ammonium lauryl sulfate, sodium laureth-2-sulfate, triethanolamine lauryl sulfate, etc.) and amphoteric surfactant systems popular in many shampoos, body washes and body washes.

With zero eye irritation test results, PEG-120 Methyl Glucose Dioleate is non-irritating to the eyes, making PEG-120 Methyl Glucose Dioleate ideal for baby shampoos.
The addition of PEG-120 Methyl Glucose Dioleate to formulas can significantly reduce eye irritation normally associated with harsh surfactants.

The multifunctionality of PEG-120 Methyl Glucose Dioleate to viscosify and reduce irritation makes PEG-120 Methyl Glucose Dioleate ideal for use in cleaning applications.
Formulators rely on PEG-120 Methyl Glucose Dioleate to create products that are easy to pour and have aesthetically pleasing foaming properties without the concern of changing foam characteristics.

PEG-120 Methyl Glucose Dioleate performs aesthetically pleasing foaming properties, creates very smooth formulations, provides high viscosity, smoothness and does not cause eye irritation.
As important, the addition of PEG-120 Methyl Glucose Dioleate Syrup thickener to formulas can significantly reduce the eye irritation normally associated with harsh surfactants.

PEG-120 Methyl Glucose Dioleate is a natural glucose derivative from corn, acting as high-efficient thickener in shampoo, body wash, facial cleanser and baby cleanser.

PEG-120 Methyl Glucose Dioleate is an extremely effective nonionic thickener for hair extremely effective nonionic thickener for hair care and skin care products.
PEG-120 Methyl Glucose Dioleate is care and skin care products.

PEG-120 Methyl Glucose Dioleate is recommended for use in shower gels, facialmended for use in shower gels, facial cleansers and shampoos.
PEG-120 Methyl Glucose Dioleate is derived from corn.

PEG-120 Methyl Glucose Dioleate is an extremely effective nonionic thickener for hair care and skin care products.
PEG-120 Methyl Glucose Dioleate is recommended for use in shower gels, facial cleansers and shampoos.

PEG-120 Methyl Glucose Dioleate is non-irritating to the eyes, making PEG-120 Methyl Glucose Dioleate ideal for baby shampoos.
PEG-120 Methyl Glucose Dioleate is the polyethylene glycol ether of the diester of methyl glucose and oleic acid with an average of 120 moles of ethylene oxide.
PEG-120 Methyl Glucose Dioleate is an ethoxylated methyl ether of corn glucose, being converted with oleic acid, resulting in the title of natural, smooth and functional non-ionic thickener.

The addition of PEG-120 Methyl Glucose Dioleate to formulas can significantly reduce the eye irritation normally associated with harsh surfactants.
PEG-120 Methyl Glucose Dioleate is used in beauty applications.

Being produced from natural, renewable and sustainable sources, PEG-120 Methyl Glucose Dioleate can be used in shower gels, facial cleansers, shampoos and baby formulas, the latter being very interesting, as Glucamate does not irritate the eyes.
PEG-120 Methyl Glucose Dioleate can be described as having more than one hydrophobic tail and one hydrophilic group, attracting surfactant molecules, thus forming bridges in surfactant micelles.
As a result, PEG-120 Methyl Glucose Dioleate has the action of reducing the CMC, which is the concentration at which free surfactant molecules begin to form micelles.

Applications of PEG-120 Methyl Glucose Dioleate:
Facial Cleansers
Hand Soap
Intimate Cleansers
Mild Cleansers
Body Wash
Shampoo

Uses Areas of PEG-120 Methyl Glucose Dioleate:

Agrochemical:
Crop & Pest Control
Disinfection / Hygiene
Horticulture

Animal Care:
Animal Nutrition
Cleaning
Odour Control

Home, Industrial & Institutional:
Air Care
Fresheners
Car Care
Polish
Shampoo
Wax
Dish Care
Automatic
Hand wash
Fabric Care
Laundry
Textiles
Precision Cleaning
Surface Care
Floor Care
Hard Surface Cleaning

Personal Care & Cosmetics:
Fragrances
Perfumes
Hair Care
Conditioning
Shampoo
Styling
Oral Care
Dental Hygiene
Shower / Bath (Rinse Off)
Cleansing Products
Skin Care & Cosmetics
Skin Care
Anti-Perspirants
Cosmeceuticals
Decorative Cosmetics
Sun Care

Pharmaceutical & Medical Devices:
Human Medicines
Inhalation
Liquid Dose
Solid Dose
Topical
Medical Devices
Natural Remedies / Dietary Supplements
Pharma
Veterinary Medicines

Food:
Bakery
Bakery Premixes
Beverages
Confectionary
Organic
Dairy
Fruit & Vegetable Processing (Including Preserves)
Meat, Fish & Poultry
Soups, Sauces & Dressings

Coatings & Construction:
Paints
Coatings
Construction
Adhesives
Concrete & Cement
Elastomers
Inks
Printing Solutions

Automotive:
Fluids
Washing
Plastics / Polymers
Precision Cleaning

Metal Treatment & Aerospace:
Lubricants
Metal Treatment
Metal Working & Machinery
Precision Cleaning
Processed Liquids

Oil & Gas:
Downstream
Drilling, Exploration & Extraction
Precision Cleaning

Textile & Leather:
Leather
Textile

Pulp & Paper:
De-Inking
Paper Processing
Pulping

Water Treatment:
Filtration & Maintenance
Drinking Water
Waste Management
Water Conditioning

Function of PEG-120 Methyl Glucose Dioleate:
PEG-120 Methyl Glucose Dioleate is a vegetable-derived highly efficient viscosity builder designed for use with numerous anionic surfactants (i.e. ammonium lauryl sulfate, sodium laureth-2 sulfate, triethanolamine lauryl sulfate, etc.) and amphoteric surfactant systems popular in many shampoos, body washes and liquid soaps.

Features/Benefits of PEG-120 Methyl Glucose Dioleate:
Broad compatibility with various surfactant systems,
Enables formulations that are easy to pour and have aesthetically-pleasing foaming properties without the worry of changing foam characteristics,

Enables very mild formulations and reduces irritation associated with certain surfactants for application around the eyes,
Highly efficient thickener of surfactant system formulations,

Naturally derived,
Very light feel.

Other Benefits:
Abrasion Resistance
Anti-acne
Anti-bacterial
Anti-wrinkle
Barrier repair
Biodegradable
Broad spectrum
Colour protection
Compressible
Cooling
Defoaming
Easy glide
Firming
Flavour enhancing
Flavour masking
Greater flowability
Heat protection
Heavy feel
High Solvency
Improved flavour profile
Improved slip
Light feel
Lubricity
Mild
Moisturising
Renewable
Scratch Resistance
Sensory
Skin soothing
Skin tone modulation
Slip
Texturing
Water-Based
Wetting

Typical Properties of PEG-120 Methyl Glucose Dioleate:
Superior ability to thicken many anionic and amphoteric surfactants.
No irritation to eye, applicable in facial cleanser and baby shampoo.

No effect on foamability.
Impart quite soft and gentle after-feeling.

Cosmetic Properties:
Very mild,
Highly efficient thickener of surfactant system formulations,
Reduces irritation associated with surfactants,
Does not reduce foam heights,
Very light feel,
Broad compatibility with various surfactant systems.

Characteristics of PEG-120 Methyl Glucose Dioleate:
PEG-120 Methyl Glucose Dioleate is a highly efficient, plant-derived viscosity builder designed for use with numerous anionic surfactants (ie, ammonium lauryl sulfate, sodium laureth-2-sulfate, triethanolamine lauryl sulfate, etc.) and amphoteric surfactant systems popular in many shampoos, body washes and liquid soaps.
With zero eye irritation test results, PEG-120 Methyl Glucose Dioleate is non-irritating to the eyes, making PEG-120 Methyl Glucose Dioleate ideal for baby shampoos.

The addition of PEG-120 Methyl Glucose Dioleate to formulas can significantly reduce eye irritation normally associated with harsh surfactants.
The multifunctionality of PEG-120 Methyl Glucose Dioleate to viscosify and reduce irritation makes PEG-120 Methyl Glucose Dioleate ideal for use in cleaning applications.
Formulators count on PEG-120 Methyl Glucose Dioleate to create products that are easy to pour and have aesthetically pleasing foaming properties without the concern of changing foam characteristics.

Handling and Storage of PEG-120 Methyl Glucose Dioleate:

Storage:
Store in tightly closed containers.
Store in an area that is dry, well-ventilated, away from incompatible materials.

Precautions for safe handling:

Measures to prevent Fire:
Avoid contact with skin, inside of the eye and clothing.
Wash hands before breaks and after handling product.

Provide sufficient air exchange and/ or exhaust in work rooms.
Keep away from heat, sparks and flame – no smoking.

Conditions for safe storage, including any incompatibilities:
Keep containers/ packages tightly closed in a cool, well ventilated place.
Avoid direct sunlight.

Avoid prolonged excessive heat and air when handling.
Mix well before using.

Handle and open containers with care.
Good housekeeping and controlling of dust are necessary for safe handling of products.

Suitable container:
Polyethylene or polypropylene container.
Check all containers are clearly labelled and free from leaks.

Stability and Reactivity of PEG-120 Methyl Glucose Dioleate:

Reactivity:
No information available.

Chemical Stability:
Unstable in the presence of incompatible materials.
Product is considered stable.
Hazardous polymerisation will not occur.

Possibility of Hazardous:
None known under recommended storage conditions and normal usage conditions.

Conditions to Avoid:
Extreme temperature.

Incompatible Materials:
Avoid reaction with oxidising agents.
Avoid strong acids, acid chlorides, acid anhydrides and chloroformates.

First Aid Measures of PEG-120 Methyl Glucose Dioleate:

Inhalation:
If respiratory irritation occurs, remove individual to fresh air.

Ingestion:
For external use only, do not swallow.
If swallowed, Drink 1 or 2 glasses of water.

Immediately see a physician.
Never give anything by mouth to an unconscious person.

Skin contact:
If necessary, remove contamination clothing.
Wash off with soap and plenty of water.
In all cases of doubt seed medical advice.

Eye contact:
Remove contacts lenses.
Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open.

Cold water may be used.
In all cases of doubt seed medical advice.

Indication of any immediate medical attention and special treatment needed:

Notes to physician:
Ensure that medical personnel are aware of PEG-120 Methyl Glucose Dioleate involved and take precautions to protect themselves.

Fire Fighting Measures of PEG-120 Methyl Glucose Dioleate:

Suitable extinguishing media:
Water spray or fog.
Foam, Dry chemical powder, BCF (where regulations permit), Carbon dioxide.

Hazardous Combustion:

Product:
Carbon oxides (COx), Nitrogen oxides(NOx)

Special hazards arising from the substance or mixture:

Fire Incompatibility:
Avoid contamination with oxidising agents i.e. nitrates, oxidising acids, chlorine bleaches, pool chlorine etc. as ignition may result.

Combustion products include:
Carbon monoxide (CO) carbon dioxide (CO2)

Advice for firefighters In the event of fire, wear a self-contained breathing apparatus and chemical resistant personal protective equipment.
Cool containers/ tanks with water spray.

Dike and collect water used to fight fire.
Keep people away from upwind of fire.

Accidental Release Measures of PEG-120 Methyl Glucose Dioleate:

Environmental precautions:
Prevent leakage or spillage.
Do not discharge products into the aquatic environment without pre-treatment.

Methods for cleaning up:

Minor Spills:
Remove all ignition sources.
Clean up all spills immediately.

Avoid contact with skin and eyes.
Control personal contact with the substance, by using protective equipment.

Use dry clean up procedures and avoid generating dust.
Place in a suitable, labelled container for waste disposal.
Slippery when split.

Major Spills:
Moderate hazard.

CAUTION:
Advise personnel in area.
Alert Emergency Services and tell them location and nature of hazard.

Control personal contact by wearing protective clothing.
Prevent, by any means available, spillage from entering drains or water courses.

Recover product wherever possible.
Slippery when spilt.

Identifiers of PEG-120 Methyl Glucose Dioleate:
Common Name: Glucamate DOE 120
CAS Number: 86893-19-8
Molecular Formula: (C2H4O)n(C2H4O)nC43H78O8

Properties of PEG-120 Methyl Glucose Dioleate:
Aspect: Flake
Color: Yellowish or white
Acid value: Max. 1.0 (mg KOH/g)
Hydroxyl value: 14.0 - 26.0 (mg KOH/g)
Saponification Value: 14.0 - 26.0 (mg KOH/g)
Iodine value(g/100g): 5 – 15 (g/100g)

Product Category: Raw material/ thickener
Raw material content: 100% natural/artificial natural
Formulation/characteristic: White flake type with transparency
odor / peculiar odor: with peculiar odor
Water/Usability: receptivity
Storage method: Storing in a cool and dark place
Recommended content: 0.5 to 5%
pH: 5.0~7.5

Synonyms of PEG-120 Methyl Glucose Dioleate:
PEG-120 methyl glucose dioleate
AEC PEG-120 METHYL GLUCOSE DIOLEATE
ANTIL 120 PLUS
GLUCAMATE DOE-120 THICKENER
MACROGOL 120 METHYL GLUCOSE DIOLEATE
PEG 120 methyl glucose dioleate
PEG-120 METHYL GLUCOSE DIOLEATE (II)
POLYETHYLENE GLYCOL (120) METHYL GLUCOSE DIOLEATE
YM0K64F20V
Glucamate DOE-120
Unimate DOEmonoethylene glycol
1,2-Dihydroxyethane
2-hydroxyethanol
Glycol alcohol
Ethylene alcohol
polyethylene glycol
Macrogol
Fridex
Tescol
Ethylene dihydrate
Norkool
Macrogol 400 BPC
Dowtherm SR 1
ethanediol
Zerex
Poly(ethylene glycol)
Ucar 17
Lutrol-9
Polyethylene glycol 200
ethyleneglycol
Aethylenglykol
Ethylenglycol
1,2-Ethandiol
1,2-ethylene glycol
1,2-dihydroxy ethane
ethylen glycol
ethylene-glycol
146AR
Polyethylene glycol 3350
UNII-FC72KVT52F
Lutrol 9
MFCD00002885
NSC 93876
Carbowax 300
PEG
HOCH2CH2OH
Union Carbide XL 54 Type I De-icing Fluid
M.e.g.
FC72KVT52F
DTXSID8020597
CHEBI:30742
1, 2-Ethanediol
DSSTox_CID_597
DSSTox_RID_75680
DSSTox_GSID_20597
Glycol, ethylene-
Glycol, polyethylene
Glycols, polyethylene
Caswell No. 441
Aethylenglykol
Polyethylene oxide
Carbowax 20
CAS-107-21-1
Polyethylene Glycols
Carbowax 400
Carbowax 1000
CCRIS 3744
Dowtherm 4000
HSDB 5012
Ethylene glycol polymer
NCI-C00920
PEG 3350
Ethylene glycol homopolymer
Polyethylene Glycol 6000
EPA Pesticide Chemical Code 042203
1,2-Ethanediol homopolymer
WLN: Q2Q
ethyleneglycole
Athylenglykol
ehtylene glycol
etylene glycol
AI3-03050
2-ethanediol
Polyaethylenglykol
Ilexan E
4-vinyl cathecol
Polyaethylenglykole
MEG 100
Solbanon (TN)
1,2-ethane diol
1,2-ethane-diol
ethane-1.2-diol
GXT
PEG 1000
PEG 4000
1,2-ethyleneglycol
ethan-1,2-diol
mono-ethylene glycol
Macrogol 400
Carbowax 1540
1,2-ethylene-glycol
Lutrol E (TN)
DuPont Zonyl FSO Fluorinated Surfactants
Ethylene glycol-[d6]
alpha-Hydro-omega-hydroxypoly(oxyethylene)
polyethylene glycol-400
Macrogol 400 (TN)
Polyethylene oxide (NF)
Polyethylene glycol (NF)
Sentry polyox WSR (TN)
Ethyleneglycol, ReagentPlus
Macrogol 1500 (TN)
Macrogol 4000 (TN)
Macrogol 6000 (TN)
EC 203-473-3
Macrogol ointment (JP17)
Glycol, polyethylene(300)
HO(CH2)2OH
NCIOpen2_001979
NCIOpen2_002019

Peg-120 methyl glucose dioleate functions as a cleansing agent and texture enhancer.
Peg-120 methyl glucose dioleate is a polyethylene glycol ether of the diester of methylglucose and oleic acid with an average of 120 moles of ethylene oxide.
Some of the most common products we use today include Peg-120 methyl glucose dioleate , such as certain shampoos, conditioners, facial cleansers, shower gels, and hand soaps.

CAS: 86893-19-8
MF: (C2H4O)mult(C2H4O)multC43H78O
EINECS: 617-932-4

Peg-120 methyl glucose dioleate is created in a lab by the acid acid-catalyzed reaction of glucose with methanol and is utilized for its emulsion and surfactant properties that has minimal absorption into the skin due to its high molecular weight.
Peg-120 methyl glucose dioleate thickener is a naturally-derived, methyl glucose ether which has been esterified with oleic acid.
Peg-120 methyl glucose dioleate is a flaked solid, highly efficient viscosity builder designed for use with numerous anionic surfactants and amphoteric surfactant systems popular in many shampoos, body washes, and liquid soaps.
Peg-120 methyl glucose dioleate thickener is non-irritating to the eyes, making it ideal for baby shampoos.
Peg-120 methyl glucose dioleate serve as consistency enhancers in lipsticks and creams as well as humectants.
Peg-120 methyl glucose dioleate well tolerated by the skin and are not microbiologically sensitive, so that in general it is not necessary to add any preservatives.
Emulsifiers are often used in cosmetics as excipients.

Peg-120 methyl glucose dioleate allow actually unmixable components like oil and water to be brought in a permanently stable emulsion.
In this way both aqueous and oily care and active ingredients can be used in one and the same product in cosmetics.
Emulsifiers are able to do that since their molecules consist of a lipophilic and a hydrophilic part.
In this way they can reduce the interfacial tension which actually exists between two incompatible substances like fat and water.
Emulsifiers are, more particularly, used for creams, lotions and cleansing agents.
At present emulsifiers are, however, more than only excipients which keep an emulsion stable.
Fatty acid esters on the basis of sugar, lecithin or glycerin monodistearate contribute, for instance, to improving the moisture balance of the skin and are, therefore, also considered as cosmetic active ingredients.

Specification
Appearance: Pale yellow flake
Odor: Mild characteristic
Acid value, mg/g: 1 max
Hydroxyl value, mg/g: 14-26
Saponification value, mg/g: 14-26
Iodine value: 5-15
pH,(1% aqueous solution): 4.5-7.5

Uses
Peg-120 methyl glucose dioleate is used as a thickener and stabilizer in hair care products like shampoo as it essentially helps to dissolve oil or grease on the skin.
Due to Peg-120 methyl glucose dioleate is thickening property PEG 120 methyl glucose dioleate is known to be an effective nonionic thickener for hair care products.
Peg-120 methyl glucose dioleate additionally provides moisture retention which can improve the skin-feel of surfactant-based products.
PEG-120 methyl glucose dioleate is used as a surfactant and emulsifier in many cosmetic products.
When used on skin Peg-120 methyl glucose dioleate forms a thin layer forming a barrier.
Peg-120 methyl glucose dioleate protects the skin from moisture loss and other external factors.
Peg-120 methyl glucose dioleate is also known to increase the water retention capacity of the skin and makes it softer and healthier.
Peg-120 methyl glucose dioleate also conditions hair and makes them appear soft and silky.
Peg-120 methyl glucose dioleate is also used as an emulsifier in cosmetic products.
Peg-120 methyl glucose dioleate gives stability to the product and prevents the oil and water-based components of the product from getting separated.
As a surfactant, Peg-120 methyl glucose dioleate helps the dirt particles trapped on the skin with oil to get mixed with water, so that it gets away rinsed easily with water.
Peg-120 methyl glucose dioleate is also used as a thickener in hair care products.

Peg-120 methyl glucose dioleate is also a noni irritant and reduces the irritation value of the cosmetic product.
Peg-120 methyl glucose dioleate is used in formulations of creams, lotions, shampoos, conditioners, bath products, cleansers, and other skin and hair care products.
PEG-120 methyl glucose dioleate is used as a surfactant and emulsifier in many cosmetic products.
Peg-120 methyl glucose dioleate provides stability to the product and prevents the oil and water-based components of the product from separating out.
Peg-120 methyl glucose dioleate is an extremely effective, non-ionic, liquid thickener that can be used in numerous surfactant and emulsion systems.
Peg-120 methyl glucose dioleate is typically used at 0.5-3%, depending on the application.
Skin care: Peg-120 methyl glucose dioleate creates a thin layer on the skin forming a barrier.
Peg-120 methyl glucose dioleate protects the skin from moisture loss and increases its water retention capacity thereby making it softer and healthier
Hair care: Peg-120 methyl glucose dioleate conditions the hair and makes them soft and silky.
As a surfactant, Peg-120 methyl glucose dioleate helps the dirt particles trapped on the skin with oil to get mixed with water, so that it gets away rinsed easily with water and is useful for shampoo formulations.
Peg-120 methyl glucose dioleate also thickens the hair product.

Synonyms
PEG-120 methyl glucose dioleate
AEC PEG-120 METHYL GLUCOSE DIOLEATE
ANTIL 120 PLUS
GLUCAMATE DOE-120 THICKENER
MACROGOL 120 METHYL GLUCOSE DIOLEATE
PEG 120 methyl glucose dioleate
PEG-120 METHYL GLUCOSE DIOLEATE (II)
POLYETHYLENE GLYCOL (120) METHYL GLUCOSE DIOLEATE
YM0K64F20V

Peg-120 methyl glucose dioleate is available as a flaky solid or a liquid.
Peg-120 methyl glucose dioleate is in white powder form and can take on a gel-like consistency when mixed with water.
Peg-120 methyl glucose dioleate is well soluble in water and water-based solvents.


CAS Number: 86893-19-8
EC Number: 617-932-4
Chem/IUPAC Name: Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, ether with methyl d-glucopyranoside 2,6-bis[(z)-9-octadecenoate]
Molecular formula: C2H4O)n(C2H4O)nC43H78O



SYNONYMS:
Antil 120 Plus, Unitol 120 Plus, PEG-120 Methyl Glucose Dioleate, Poly(oxy-1,2-ethanediyl),a-hydro-w-hydroxy-, ether with methylD-glucopyranoside 2,6-di-9-octadecenoate (2:1), (Z,Z)-



Peg-120 methyl glucose dioleate is the polyethylene glycol ether of the diester of natural Methylglucose and Oleic Acid.
Peg-120 methyl glucose dioleate is used in beauty products and cosmetics as a surfactant and emulsifier.
Peg-120 methyl glucose dioleate is used as a thickener in hair and skin care products.


Peg-120 methyl glucose dioleate is considered a non-irritant, and also has a specific property that allows it to reduce the irritation value of whole formulas.
Peg-120 methyl glucose dioleate is a polyethylene glycol ether of the diester of methylglucose and oleic acid with an average of 120 moles of ethylene oxide.


Peg-120 methyl glucose dioleate is considered a non-irritant, and also has a specific property that allows it to reduce the irritation value of whole formulas.
Peg-120 methyl glucose dioleate is FDA and CIR approved for use, but not on broken skin.


Peg-120 methyl glucose dioleate is the polyethylene glycol ether of the diester of natural Methylglucose and Oleic Acid.
Peg-120 methyl glucose dioleate can reduce the irritation value of the entire formulation.
Its high molecular weight makes Peg-120 methyl glucose dioleate impenetrable to healthy skin.


Peg-120 methyl glucose dioleate is available as a flaky solid or a liquid.
Peg-120 methyl glucose dioleate is in white powder form and can take on a gel-like consistency when mixed with water.
Peg-120 methyl glucose dioleate is well soluble in water and water-based solvents.


Peg-120 methyl glucose dioleate is generally used as a thickener in cosmetic products.
Peg-120 methyl glucose dioleate has the potential to provide viscosity to products.
Peg-120 methyl glucose dioleate helps retain water in the skin.


Peg-120 methyl glucose dioleate has moisturizing potential.
Peg-120 methyl glucose dioleate is a polyethylene glycol ether of the diester of methylglucose and oleic acid with an average of 120 moles of ethylene oxide.


Peg-120 methyl glucose dioleate is a combination of polyethylene glycol ether and natural Methyl glucose and oleic acid diester.
Peg-120 methyl glucose dioleate is a high molecular weight compound that is less effective at penetrating deeper layers of the skin.
Peg-120 methyl glucose dioleate is a polyethylene glycol ether of natural methyl glucose and oleic acid diester.


Peg-120 methyl glucose dioleate is used as a surfactant and emulsifier in beauty products and cosmetics.
Peg-120 methyl glucose dioleate is used as a thickening agent in hair and skin care products.
Peg-120 methyl glucose dioleate is considered non-irritating and also has specific properties that reduce the irritation value of the entire formula.


Peg-120 methyl glucose dioleate functions as a cleansing agent and texture enhancer.
Peg-120 methyl glucose dioleate is a flaked solid, highly efficient viscosity builder designed for use with numerous anionic surfactants and amphoteric surfactant systems popular in many shampoos, body washes, and liquid soaps.


Peg-120 methyl glucose dioleate can reduce the irritation value of the entire formulation.
Peg-120 methyl glucose dioleate is used as an emulsifier in many cosmetic products.
Peg-120 methyl glucose dioleate provides stability to the product and prevents the oil and water-based components of the product from separating out.


Peg-120 methyl glucose dioleate is an extremely effective, non-ionic, liquid thickener that can be used in numerous surfactant and emulsion system
A surfactant is a substance that makes two liquids mix more easily, like oil and water.
Surfactants are often used in shampoos and conditioners because they are effective at removing dirt from hair without drying it out too much or causing buildup on your scalp, which can lead to dandruff and other problems.


Mild surfactants like Peg-120 methyl glucose dioleate are less likely than harsher ones to cause irritation or allergic reactions, which makes it ideal for people with sensitive skin or allergies.
Peg-120 methyl glucose dioleate is a fatty acid that can be derived from natural sources.


Peg-120 methyl glucose dioleate is a mild surfactant that's used in personal care and cosmetic products.
Peg-120 methyl glucose dioleate is the polyethylene glycol ether of the diester of natural Methylglucose and Oleic Acid, it is naturally-derived, methyl glucose ether which has been esterified with oleic acid.


Peg-120 methyl glucose dioleate is also known as Bluecam DOE-120.
Research has shown that Peg-120 methyl glucose dioleate is not only safe but can improve the health of the skin.
Peg-120 methyl glucose dioleate is a fatty acid that makes up part of the stratum corneum (the outermost layer of skin).


When applied topically, Peg-120 methyl glucose dioleate penetrates this layer and works as an emollient to help keep moisture in and prevent dehydration.
Peg-120 methyl glucose dioleate is a water-soluble emollient that creates a protective barrier on the skin.
Peg-120 methyl glucose dioleate does not absorb into the skin, so there are no side effects such as irritation, acne, or dryness.


Peg-120 methyl glucose dioleate also has anti-inflammatory properties and can help to reduce swelling in your skin.
Peg-120 methyl glucose dioleate is the polyethylene glycol ether of the diester of natural Methylglucose and Oleic Acid.
Peg-120 methyl glucose dioleate, commonly known as DOE-120 in the market, is a highly efficient thickener for anionic and amphoteric surfactant formulations.


Peg-120 methyl glucose dioleate is pale yellow flake,with mild characteristic odor.
Peg-120 methyl glucose dioleate is surfactant based,reduces irritation associated with surfactants, it does not reduce foam heights.
Peg-120 methyl glucose dioleate has very light feel.


Peg-120 methyl glucose dioleate can provides gelling and moisturization.
Peg-120 methyl glucose dioleate is a slight yellow waxy solid
Peg-120 methyl glucose dioleate is a combination of polyethylene glycol ether and the natural diolether of methyl glucose and oleic acid.


Peg-120 methyl glucose dioleate is a high molecular weight compound that penetrates less effectively into the deeper layers of the skin.
Peg-120 methyl glucose dioleate is a naturally-derived, methyl glucose ether which has been esterified with oleic acid.
Peg-120 methyl glucose dioleate is a flaked solid, highly efficient viscosity builder designed for use with numerous anionic surfactants and amphoteric surfactant systems popular in many shampoos, body washes, and liquid soaps.


Peg-120 methyl glucose dioleate is non-irritating to the eyes, making it ideal for baby shampoos.
Peg-120 methyl glucose dioleate is a naturally derived cleansing and thickening agent for shampoos and other cleansing products.
Peg-120 methyl glucose dioleate also has good moisture retention properties which can help it improve the skin-feel of surfactant-based products.


Peg-120 methyl glucose dioleate is derived from corn and palm and then ethoxylated to make it water soluble.
Ethoxylation is usually a petrochemical process.
Peg-120 methyl glucose dioleate is also known as Bluecam DOE-120.



USES and APPLICATIONS of PEG-120 METHYL GLUCOSE DIOLEATE:
Peg-120 methyl glucose dioleate is used in skin care and hair care products as a surfactant and emulsifier.
Peg-120 methyl glucose dioleate is used in cosmetics as a surfactant, thickener, and emulsifier.
Peg-120 methyl glucose dioleate is a natural glucose derivative from corn, acting as high-efficient thickener in shampoo, body wash, facial cleanser and baby cleanser.


Peg-120 methyl glucose dioleate imparts a soft and gentle after feel.
Peg-120 methyl glucose dioleate is especially applicable in shampoo, body wash and facial cleanser.
Peg-120 methyl glucose dioleate can also be made from coconut oil, for example, and then used as an ingredient in cosmetics or skin cleansers.


Peg-120 methyl glucose dioleate uses and characteristics
Peg-120 methyl glucose dioleate is used as a surfactant to improve the viscosity, shelf life, and stability of skin cleansers and other cosmetic products.
Peg-120 methyl glucose dioleate also helps to create foam in personal care products such as shampoos, shower gels, and bubble baths.


Peg-120 methyl glucose dioleate is also known for being non-comedogenic, this kind of ingredients are preferred by people with oily or acne-prone skin, as they are less likely to clog pores.
Additionally, non-comedogenic ingredients are also preferred by people with sensitive skin because they do not contain harsh chemicals that could irritate the skin.


Its mildness makes Peg-120 methyl glucose dioleate an ideal choice for sensitive skin, so it's great for those with eczema or rosacea.
Peg-120 methyl glucose dioleate can also be used on babies who have sensitive skin and even babies with cradle caps.
Peg-120 methyl glucose dioleate is used in beauty products and cosmetics as a surfactant, emulsifier and viscosity modifier.


Peg-120 methyl glucose dioleate is used as a thickener in hair and skin care products such as shampoo, body, and hand washes.
Peg-120 methyl glucose dioleate is considered a non-irritant, and also has a specific property that allows it to reduce the irritation value of whole formulas.


Peg-120 methyl glucose dioleate is used as Cosmetic Raw Material.
Peg-120 methyl glucose dioleate functions as a cleansing agent and texture enhancer.
Peg-120 methyl glucose dioleate is a natural glucose derivative from corn, acting as high–efficient thickener in shampoo, body wash, facial cleanser and baby cleanser.


Peg-120 methyl glucose dioleate is especially applicable to some surfactants hardly to thicken.
Peg-120 methyl glucose dioleate causes no irritation to eyes, meanwhile significantly reduces irritation of whole formula.
Peg-120 methyl glucose dioleate is used Shampoo, body wash, facial cleanser.


Peg-120 methyl glucose dioleate is used as a surfactant and emulsifier in many cosmetic products.
When applied to the skin, Peg-120 methyl glucose dioleate creates a thin layer that creates a barrier.
Peg-120 methyl glucose dioleate protects the skin from moisture loss and other external factors.


Peg-120 methyl glucose dioleate is also known that it increases the water retention capacity of the skin, making it smoother and healthier.
Peg-120 methyl glucose dioleate also softens the hair, making it soft and silky.
Peg-120 methyl glucose dioleate is also used as an emulsifier in cosmetic products.


Peg-120 methyl glucose dioleate provides stability to the product and prevents the oil and water components of the product from stratifying.
As a surfactant, Peg-120 methyl glucose dioleate helps oil and dirt particles that come into contact with the skin mix with water so they can be easily washed off with water.


Peg-120 methyl glucose dioleate is also used as a thickener in hair care products.
Peg-120 methyl glucose dioleate also reduces the irritating effect of the cosmetic product.
Peg-120 methyl glucose dioleate is used in the formulation of creams, lotions, shampoos, conditioners, bath products, detergents and other skin and hair care products.


Peg-120 methyl glucose dioleate is used as a thickening and cleansing agent for shampoos and cleansing products.
Peg-120 methyl glucose dioleate is supplied in a flake form, packed in drums, and can be easily handled during transportation and storage.
Peg-120 methyl glucose dioleate functions as a cleansing agent and texture enhancer.


Peg-120 methyl glucose dioleate is naturally derived and non-irritating to the skin and eyes, making it a perfect viscosity builder for mild formulations, such as baby shampoo and baby bubble bath lotion.
Peg-120 methyl glucose dioleate also has excellent compatibility with a broad range of surfactants, which enables great flexibility in formulating.


-Hair care:
Peg-120 methyl glucose dioleate conditions the hair and makes them soft and silky.
As a surfactant, Peg-120 methyl glucose dioleate helps the dirt particles trapped on the skin with oil to get mixed with water, so that it gets away rinsed easily with water and is useful for shampoo formulations.
Peg-120 methyl glucose dioleate also thickens the hair product



USAGE AND BENEFITS OF PEG-120 METHYL GLUCOSE DIOLEATE:
Peg-120 methyl glucose dioleate is used as a surfactant and emulsifier in many cosmetic products.
When used on the skin, Peg-120 methyl glucose dioleate creates a thin layer that creates a barrier.
Peg-120 methyl glucose dioleate protects the skin from moisture loss and other external factors.


Peg-120 methyl glucose dioleate is also known to increase the water retention capacity of the skin, making it softer and healthier.
Peg-120 methyl glucose dioleate also softens the hair and makes it look soft and silky.
Peg-120 methyl glucose dioleate is also used as an emulsifier in cosmetic products.


Peg-120 methyl glucose dioleate gives stability to the product and prevents the oil and water-based components of the product from separating.
As a surfactant, Peg-120 methyl glucose dioleate helps oil and dirt particles trapped in the skin mix with water so that they are easily removed when rinsed with water.


Peg-120 methyl glucose dioleate is also used as a thickener in hair care products.
Peg-120 methyl glucose dioleate is also non-irritating and reduces the irritation value of the cosmetic product.
Peg-120 methyl glucose dioleate is used in the formulations of creams, lotions, shampoos, conditioners, bath products, cleansers and other skin and hair care products.


Peg-120 methyl glucose dioleate is used as a thickener and stabiliser in some of our shampoos as it essentially helps to dissolve oil or grease on the skin.
The high molecular weight of this specific PEG makes it impenetrable to healthy skin.
The usage rate of Peg-120 methyl glucose dioleate varies between 0.5% and 2% depending on the demonstrative effect of the product and its interaction with other substances.



WHAT IS PEG-120 METHYL GLUCOSE DIOLEATE USED FOR?
Peg-120 methyl glucose dioleate is used as a surfactant and emulsifier in many cosmetic products.
Peg-120 methyl glucose dioleate provides stability to the product and prevents the oil and water-based components of the product from separating out.

Peg-120 methyl glucose dioleate is an extremely effective, non-ionic, liquid thickener that can be used in numerous surfactant and emulsion systems.
Peg-120 methyl glucose dioleate is typically used at 0.5-3%, depending on the application.


*Skin care:
Peg-120 methyl glucose dioleate creates a thin layer on the skin forming a barrier.
Peg-120 methyl glucose dioleate protects the skin from moisture loss and increases its water retention capacity thereby making it softer and healthier


*Hair care:
Peg-120 methyl glucose dioleate conditions the hair and makes them soft and silky.
As a surfactant, Peg-120 methyl glucose dioleate helps the dirt particles trapped on the skin with oil to get mixed with water, so that it gets away rinsed easily with water and is useful for shampoo formulations.
Peg-120 methyl glucose dioleate also thickens the hair product



ORIGIN OF PEG-120 METHYL GLUCOSE DIOLEATE:
Peg-120 methyl glucose dioleate is manufactured via the transesterification of an appropriate fatty acid methyl ester with methyl glucoside.



WHAT DOES PEG-120 METHYL GLUCOSE DIOLEATE DO IN A FORMULATION?
*Emulsifying
*Surfactant



SAFETY PROFILE OF PEG-120 METHYL GLUCOSE DIOLEATE:
Safety profile
Peg-120 methyl glucose dioleate is considered to be safe for use in cosmetics.



ALTERNATIVES OF PEG-120 METHYL GLUCOSE DIOLEATE:
*COCAMIDOPROPYL BETAINE,
*LAURYL BETAINE,
*DECYLTETRADECETH200 BEHENATE,
*GLYCERYL ISOSTEARATE,
*CAPRYLIC CAPRIC GLYCERIDES



FUNCTIONS OF PEG-120 METHYL GLUCOSE DIOLEATE:
Emulsifying :
Peg-120 methyl glucose dioleate promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil)



FUNCTIONS OF PEG-120 METHYL GLUCOSE DIOLEATE IN COSMETIC PRODUCTS:
*CLEANSING
Peg-120 methyl glucose dioleate cleans skin, hair or teeth

*SKIN CONDITIONING - EMOLLIENT
Peg-120 methyl glucose dioleate softens and smoothens the skin

*VISCOSITY CONTROLLING
Peg-120 methyl glucose dioleate increases or decreases the viscosity of cosmetic products



OCCURRENCE IN COSMETICS OF PEG-120 METHYL GLUCOSE DIOLEATE:
Face toners, aftershaves and hair tonics, as solvent and solubiliser for active ingredients, perfume oils and colourants, humectants, basis for creams, as consistency enhancer, binding agent, softening agent and fixative



PROPERTIES OF PEG-120 METHYL GLUCOSE DIOLEATE:
1. Superior ability to thicken many anionic and amphoteric surfactants.
2. No irritation to eye, applicable in facial cleanser and baby shampoo.
3. No effect on foamability.
4. Impart quite soft and gentle after-feeling.



FEATURES AND APPLICATIONS OF PEG-120 METHYL GLUCOSE DIOLEATE:
Peg-120 methyl glucose dioleate is a natural glucose derivative from corn, acting as high-efficient thickener in shampoo, body wash, facial cleanser and baby cleanser.
Peg-120 methyl glucose dioleate is especially applicable to some surfactants hardly to thicken.
Peg-120 methyl glucose dioleate causes no irritation to eyes, meanwhile significantly reduces irritation of whole formula.
Peg-120 methyl glucose dioleate has superior ability to thicken many anionic and amphoteric surfactants.



FUNCTION OF PEG-120 METHYL GLUCOSE DIOLEATE:
Peg-120 methyl glucose dioleate is a sugar-based rheological additive for aqueous surfactant systems.
Peg-120 methyl glucose dioleate is suitable for many formulations such as hair shampoos, shower gels, foam baths, liquid soaps or hand wash pastes.



PROPERTIES OF PEG-120 METHYL GLUCOSE DIOLEATE:
*Superior ability to thicken many anionic and amphoteric surfactants.
*No irritation to eye, applicable in facial cleanser and baby shampoo.
*No effect on foamability.
*Impart quite soft and gentle after-feeling.



COSMETIC FUNCTIONS OF PEG-120 METHYL GLUCOSE DIOLEATE:
*Surfactant
*Cleansing Agent
*Emulsifying



FUNCTIONS OF PEG-120 METHYL GLUCOSE DIOLEATE IN COSMETIC PRODUCTS:
*SURFACTANT - EMULSIFYING
Peg-120 methyl glucose dioleate allows the formation of finely dispersed mixtures of oil and water (emulsions)



ORIGIN OF PEG-120 METHYL GLUCOSE DIOLEATE:
Peg-120 methyl glucose dioleate is a synthetic



SOLUBILITY OF PEG-120 METHYL GLUCOSE DIOLEATE:
Peg-120 methyl glucose dioleate is soluble in hot water.
Peg-120 methyl glucose dioleate comes as flakes that will soften and dissolve into a water base but this can be quite slow at room temperature.
The best procedure is to heat a little of your water to 50-60C and add the Peg-120 methyl glucose dioleate, forming a fluid paste which can then be added into the rest of your formula for thickening.



FEATURES AND BENEFITS OF PEG-120 METHYL GLUCOSE DIOLEATE:
*Highly efficient in thickening surfactant system formulations; Broad compatibility with various surfactants.
*No irritation to eye, applicable in facial cleanser and baby shampoo.
*No effect on foam characteristics of surfactant systems.
*Imparts light, soft and gentle feeling after washing.



WHAT DOES PEG-120 METHYL GLUCOSE DIOLEATE DO IN SHAMPOO?
Peg-120 methyl glucose dioleate is used as a thickener and stabilizer in hair care products like shampoo as it essentially helps to dissolve oil or grease on the skin.
Due to its thickening property Peg-120 methyl glucose dioleate is known to be an effective nonionic thickener for hair care products.
Peg-120 methyl glucose dioleate additionally provides moisture retention which can improve the skin-feel of surfactant-based products.



IS PEG-120 METHYL GLUCOSE DIOLEATE GOOD FOR SKIN AND HAIR?
Though Peg-120 methyl glucose dioleate has some positive benefits, it is also used in spray-on oven cleaners to dissolve oil and grease.
These petroleum-derived compounds can reduce your skin’s natural moisture.
This can increase the appearance of aging and leave your skin and hair vulnerable to harmful bacteria.



IS PEG-120 METHYL GLUCOSE DIOLEATE THE SAME AS METHANOL?
Peg-120 methyl glucose dioleate and methanol can achieve the similar result of degreasing the skin or hair but have very different general purposes.
While Peg-120 methyl glucose dioleate is used within every cleaning and hygiene products, methanol is used in adhesives, pharmaceuticals, and agrichemicals.
Methanol can cause light to severe reactions ranging from headaches and conjunctivitis to blindness, birth defects and death.



PHYSICAL and CHEMICAL PROPERTIES of PEG-120 METHYL GLUCOSE DIOLEATE:
Boiling Point: >200°C
Solubility: Soluble in water



FIRST AID MEASURES of PEG-120 METHYL GLUCOSE DIOLEATE:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of PEG-120 METHYL GLUCOSE DIOLEATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of PEG-120 METHYL GLUCOSE DIOLEATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of PEG-120 METHYL GLUCOSE DIOLEATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of PEG-120 METHYL GLUCOSE DIOLEATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of PEG-120 METHYL GLUCOSE DIOLEATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available

PEG-150, N° CAS : 25322-68-3, polyethylene glycol (200-600) , CAS : 25322-68-3; Synonymes : polyethylene glycol (200-600);PEG;Polymère d'oxyéthylène;Poly(oxy-1,2-éthynediyl), alpha-hydro-oméga-hydroxy;Oxyethylene polymer.Nom INCI : PEG-150, Additif alimentaire : E1521, Classification : PEG/PPG, Composé éthoxylé, Glycol, Polymère de synthèse. Ses fonctions (INCI); Agent fixant : Permet la cohésion de différents ingrédients cosmétiques. Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau. Solvant : Dissout d'autres substances. Noms français : ALPHA-HYDRO-OMEGA-HYDROXYPOLY(OXY-1,2-ETHANEDIYL); POLY(ETHYLENE OXIDE); POLYETHYLENE GLYCOL 3350; POLYETHYLENE GLYCOL ; CARBOWAX SENTRY 3350, FLOCONS; POLYETHYLENE GLYCOL CARBOWAX SENTRY 3350, POUDRE; POLYETHYLENEGLYCOL 600. Polyéthylène glycol solide. Noms anglais : SOLID POLYETHYLENE GLYCOL. Utilisation et sources d'émission : Fabrication de produits pharmaceutiques, fabrication de cosmétiques

poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-[(1-oxooctadecyl)oxy]- (150 mol EO average molar ratio); polyethylene glycol (150) distearate; polyoxyethylene (150) distearate cas no: 9005-08-7

PEG-150 STEARATE, N° CAS : 9004-99-3, Origine(s) : Synthétique, Nom INCI : PEG-150 STEARATE Classification : PEG/PPG, Composé éthoxylé, Glycol, Polymère de synthèse Ses fonctions (INCI) Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation

Peg-180 is a polymer of ethylene oxide.
Peg-180 is a polyethylene glycol that conforms to the general formula HO(CH2CH2O)nH, and is especially suited for the demands of the cosmetics industry, and is supplied in flakes.


CAS Number: 25322-68-3
EC Number: 500-038-2
Chem/IUPAC Name: Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (180 mol EO average molar ratio)
Food additive: E1521
Classification: PEG/PPG , Ethoxylated compound , Glycol , Synthetic polymer
Chemical Family: Polyethylene Glycols, Polyols


Peg-180 polyethylene glycol with an average molecular weight of 8000.
Peg-180 is a solid in powder form.
Peg-180 is suitable as a medium for the fusion of mammalian cells.


Peg-180 has a wide range of uses including cell fusion for the formation of hybridomas, precipitation of DNA, and to create macromolecular crowding in solutions.
Peg-180 is a surfactant easily chosen for applications in many industries due to its properties.


Peg-180 is used as a base in the formulation of soap sticks.
Peg-180 has low glycol content and higher crystalinity.
Peg-180 is a solid white to light yellow wax with a faint but characteristic odour.


Peg-180 is very soluble in water.
The 10% aqueous solution of Peg-180 has a homogeneous and clear liquid form.
Ultrapure white crystals for molecular biology applications such as precipitation of DNA, nucleic acids, hybridization and fusion of mammalian cells.


Working concentrations of Peg-180 range from 13% to 40% (w/v).
Prepare the appropriate concentration by dissolving Peg-180 in sterile H2O, warming if necessary.
Sterilize the solution by passing Peg-180 through a 0.22-μm filter.


Peg-180 stores the solution at room temperature.
Peg-180 is store at room temperature.
Peg-180 is white granular.


Peg-180 is equally soluble in water as well as lower aliphatic alcohols such as methanol or ethanol.
The molar mass of the compound is high, ie approx. 8000 g/mol.
Density approx. 1.08 g/mL (at 70ᵒC), the solidification point of


Peg-180 is approx. 55ᵒC.
Peg-180 is safe, non-toxic and non-irritating.
Peg-180 flakes is a product belonging to the group of polyoxyethylene glycols (PEG with an average molecular weight of 8000).


Resistant to bacterial erosion, moisture absorption in the atmosphere is weak.
Peg-180 is a mixture of ethylene oxide and water polycondensation.
Peg-180 is available in the form of white to light yellow wax.


The solidification point of the product is approximately 55 °C.
Peg-180 dissolves freely in water and in low aliphatic alcohols.
Peg-180 is safe, non-toxic and does not cause skin irritation.


Peg-180 can blend with other PEG molecular weights to achieve the desired viscosity properties.
Peg-180 is quite stable and does not support microbial growth, even in aqueous solutions.
Peg-180 has a density (70°C) of approx. 1.09 g/cm^3, a clear melting point of approx. 63°C, and a flash point of approx. > 300°C.


Peg-180 is a solid in powder form.
Peg-180 is a milled PEG excipient grade powder product, produced under IPEC GMP conditions.
Peg-180 supports the homogeneous mixing with other materials within production.


Peg-180 is soluble in water.
Peg-180 is soluble in water, soluble in some organic solvents.
The solution has high viscosity at low concentration, and Peg-180 can be processed by calendering, extrusion, casting, etc.


Peg-180 is a thermoplastic resin with good compatibility with other resins.
Peg-180 is a water-soluble polyether alcohol that can be employed as a solubilizer and viscosity control agent in a variety of applications.
The freezing point of Peg-180 is 33~38°C.


Peg-180, a hydrophilic polymer, is easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups.
Peg-180 (another name - Polyethylene glycol, also known as polyethylene oxide or polyoxyethylene , Polyethylene glycol 8000) in the form of scales (flakes) belongs to the group of polyoxyethylene glycols (PEG), whose average molecular weight is 8000.


Peg-180 acts as a solvent and plasticizer.
Peg-180 shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Peg-180 is a yellow solid in fine powder form.


Peg-180 is a colorless or almost colorless viscous liquid, or a translucent waxy soft object; slightly odorless.
Peg-180 is soluble in water or ethanol, insoluble in ether.
Peg-180 is soluble in water (500 g/l at 20° C), aromatic hydrocarbons (very soluble), aliphatic hydrocarbons (slightly soluble), and organic solvents.


Peg-180 is a water-soluble, waxy solid that is used extensively in the several industries.
Peg-180 is a polyethylene glycol having white to off white color and available in solid flakes or powder form.
Ultrapure white crystals for molecular biology applications such as precipitation of DNA, nucleic acids, hybridization and fusion of mammalian cells.


The molecular formula is expressed as HO(CH2CH2O)nH, where n represents the average number of oxyethylene groups.
Peg-180 consists of wax flakes, which range in color from white to pale yellow.
The solidification point of Peg-180 is approximately 55 °C.


Peg-180 is water soluble and also soluble in many organic solvents like aromatic hydrocarbons.
Peg-180 is soluble in water and polar organic solvents like acetone or methanol.
Peg-180 is insoluble in pure hydrocarbons.


On being incorporated into networks by crosslinking, Peg-180 can have high water content, forming “hydrogels”.
Hydrogel formation can be initiated by either crosslinking it by ionizing radiation or by covalent crosslinking of Peg-180 macromers with reactive chain ends.


Peg-180 is compatible with cellulose, rubber, polyester and polyurethane.
Peg-180 is Suitable for use in papers, adhesives and sealants.
Peg-180 is specified according to the requirements of the main international ICH guidelines and monographs.


The physical and chemical properties of polyethylene glycols are mainly determined by the two hydroxyl end groups, the ether groups as well as the molecular weight.
Peg-180 shows typical chemical reactions of alcohols/diols and a very low evaporation rate.


The solidification point of Peg-180 is about 58 °C.
Peg-180 is a non-volatile solvent, release agent, lubricant and plasticizer.
Peg-180 shows typical chemical reactions of alcohols/diols and a very low evaporation rate.


Peg-180 has very low water content and outstanding toxicological safety.
Peg-180 is freely soluble in ethyl ether, chloroform, low-alcohol alcohols and water.
A big advantage of Peg-180 in the form of flakes is easy dosing , storage and the absence of costs associated with heating the storage tank .


Peg-180 is suitable for paints and coatings.
Peg-180 is a non-volatile solvent, release agent, lubricant and plasticizer.
Peg-180 shows typical chemical reactions of alcohols/diols and a very low evaporation rate.


Peg-180 is a yellowish wax-like solid at room temperature.
Peg-180 is soluble in water and polar organic solvents like acetone or methanol.
Peg-180 is insoluble in pure hydrocarbons.


Peg-180 is compatible with hard water, cellulose, polyester, rubber, elastomer and polyurethane.
Peg-180 is only on request and the total price, including shipping, is calculated individually.
Peg-180 is a polyethylene glycol-based solvent, humectant and plasticizer.


Peg-180 possesses very low water content and good solubility in water.
Peg-180 is compatible with hard water, cellulose, polyester, rubber, elastomer and polyurethane.
Peg-180 is a solid in powder form.


Polyethylene glycol (PEG) is a synthetic polymer formed from repeating units of ethylene oxide.
Peg-180 is a specific type of PEG with an average molecular weight of 8000 g/mol.
Peg-180 is hygroscopic.



USES and APPLICATIONS of PEG-180:
Besides the beauty industry, Peg-180 is used in lubricants or synthetic fluids designed for processing.
Peg-180 is also a component of heat transfer fluids.
Similar to other compounds belonging to the broad PEG group,


Peg-180 has good anti-adhesive properties used in rubber and elastomer processing.
They allow the casting to be separated from the mold more effectively, saving raw materials and time without damaging the casting.
This results in a major improvement in rubber processing.


Peg-180 is used in the modification of therapeutic proteins and peptides to enhance it's solubility.
In gas chromatography, Peg-180 is used as a polar stationary phase.
Peg-180 finds application in blood banking as a potentiator, which is used to detect antigens and antibodies.


Peg-180 is also a component used in electroplating processes.
Peg-180 is also used as an auxiliary agent in the textile industry.
Peg-180 is a compound used to modify therapeutic proteins and peptides to increase their solubility.


Peg-180 is also used to precipitate bacteriophage from lysed cell supernatants.
Peg-180 is often used as a polar stationary phase for Gas Chromatorgraphy.
Peg-180 is used as a surfactant, emulsifier and solubilizer in various industries, including cosmetics, pharmaceuticals and food.


Peg-180 is used in cosmetics as a thickener and as a humectant to help retain moisture in the skin.
In the pharmaceutical industry, Peg-180 is used as a drug delivery agent and as a lubricant for medical instruments.
In the food industry, Peg-180 is used as an emulsifier to mix oils and water-soluble ingredients.


Peg-180 is also used in ceramic processes.
Peg-180 acts as a plasticizer and binder.
Peg-180 is widely used as a mould release agents and lubricants for rubber industry.


Peg-180 is also used to preserve objects that have been retrieved from the ocean.
Peg-180 can be easily applied and removed since they are water-soluble.
Peg-180 is used as antistatic agent and lubricant in textile industry.


Peg-180 is a safe solvent and carrier for use in cosmetics can act as a solvent in many substances.
Peg-180 is also a secure carrier.
The Food and Drug Administration has issued a positive opinion on the use of Peg-180 as an indirect food additive.


For this reason, Peg-180 is used in the production of biopolymer-based food packaging.
End Uses of Peg-180: Metalworking Fluids
Peg-180 is also a secure carrier.


Peg-180 is used as a solvent (solvent) or a conductor (carrier) in all kinds of cosmetics.
Peg-180's high molecular weight mainly prompts its use in pharmaceutical formulations as solvent for oral, topical and parenteral preparations.
Peg-180 is used in hair care products such as shampoos, serums or masks.


There Peg-180 acts as a humidifier.
Peg-180 are also used as binder and dry lubricant for manufacturer of pills and tablets for certain pharmaceutical products.
Peg-180 is used as mold release agent and lubricant in fabricating elastomers.


Peg-180 is used Hair Conditioner, Cleaning Agent, Bath Oils, Tablets & Salts, Hair Styling Products, Detanglers, Antiperspirants & Deodorants, Anti-Aging Products, Cosmetics, Detergents in the form of tablets, Production of packaging, Metalworking, Construction industry, Textile industry, Processing of plastics and elastomers, Production of ceramics, and Coatings.


Peg-180 is used Binder for ceramics, Component of auxiliaries for fiber, textile and leather processing, and Heat transfer medium.
Peg-180 is responsible for keeping the humidity at the right level.
Thus, when products containing Peg-180 are applied, the hair is fed much more and maintains its natural shine.


Peg-180 is used Laboratory chemicals, Manufacture of substances, Adhesives, Ceramic Binder, Chemical Intermediates, Detergents and Household Cleaners, Dye Carrier, Lubricants, Mining, Mold Release Agent, Plasticizer, Wood Treating, Rubber, Textile, Paper, Metal, Wood, Pharmaceutical, Cosmetics, and Coating.
Peg-180 is commonly also used in mass spec experiments.


As a dispersant, Peg-180 is used in toothpastes.
Peg-180 is also used as a thickening agent in beauty cosmetics.
Crystallization grade Peg-180 for formulating screens or for optimization.


In pharmaceutical industry, Peg-180 is used as tablet and capsule lubricant.
Peg-180 is also used in the fabrication of bioactive and immuno isolating barriers for encapsulation of cells.
Peg-180 is a suitable compound with a wide scope in biological applications since Polyethylene glycol 8000 does not elicit any immune responses.


Peg-180 is vastly used for the isolation of plasmid DNA and the precipitation of phage.
Peg-180 is easily chosen by the formulators of the cosmetic industry due to its ease of application or its properties that change the viscosity of the formulations.


Peg-180 is a safe solvent and carrier for use in cosmetics can act as a solvent in many substances.
Peg-180 has been shown to modify therapeutic proteins and peptides for enhanced solubility.
Besides its use in care cosmetics, Peg-180 is used as a component of dishwasher or laundry tablets.


Peg-180 is used as Reactant: Reactive diol/polyether component in polyester or polyurethane resins
Peg-180 is used as Solvent / Humectant / Plasticizer: Paper, wood, cellulose films, inks, paints, coatings, adhesives, and sealants, concrete.
Peg-180 is used as Release agent: Lubricant mould release agent for rubber and elastomer processing, lubricant formulations, metal working fluids.


Peg-180, NF acts as a lubricant, coating the surfaces in aqueous and non-aqueous environments.
Research or further manufacturing, Peg-180 is used only, not for food or drug use.
Peg-180 is used as matrix in pharmaceutical and cosmetic industry to regulate viscosity and melting point.


In fabricating elastomers, Peg-180 can be used as a lubricant and mold releasing agent.
In pharmaceuticals, Peg-180 can function as a tablet and capsule lubricant.
Peg-180 are produced to meet the requirements for use under Food Additive Regulations for indirect use as components of articles intended for use in contact with food.


Additionally, photopolymerized Peg-180 hydrogels have emerging applications in the fabrication of bioactive and immune-isolating barriers for encapsulation of cells.
Peg-180 acts as a carrier of active substances and also as a binder.


Cosmetic Uses: viscosity controlling agents
Peg-180 that has wide application ranging from industrial manufacturing and medicine.
Peg-180 is generally used in the precipitation of phage.


Peg-180 is used for the isolation of plasmid DNA and the precipitation of phage.
As a softening and anti-electrostatic agent, Peg-180 is primarily used in the household chemicals, ceramics, paper, beauty and metal industries.
Peg-180 is a non-ionic polymer of polyethylene glycol, water soluble, which acts as a lubricating and sliding agent in cosmetic formulations in general.


Peg-180 is used as lubricant and coolant in rubber and metal processing industry, dispersant and emulsifier in pesticide and pigment industry production.
Peg-180 is also used as a fusogen (induces cell hybridization) to obtain hybridomas for monoclonal antibody production.
In addition to being soft to the touch and non-irritating, Peg-180 is compatible with a wide variety of ingredients.


Peg-180 can be incorporated into creams, gels, creamy lotions and tonics, shampoos, conditioners and other hair care products.
Peg-180 is a polyethylene glycol-based solvent, humectant and plasticizer.
Peg-180 possesses very low water content and good solubility in water.


Peg-180 is used Washing powders and tabs, Dissolving aids, Tabletting and granulation auxiliaries, Binding agents, and Toilet blocks.
The polyethylene glycol polymers are used in a wide variety of products including bath products, shaving products, skin care products, makeup, skin cleansing products, shampoo, hair conditioners and deodorants.


PEG has excellent lubricity, moisturizing, dispersion, adhesion, can be used as an antistatic agent and softener, and has a wide range of applications in cosmetics, pharmaceuticals, chemical fiber, rubber, plastics, papermaking, paint, electroplating, pesticides, metal processing and food processing industries.


PEG is widely used in various fields, from industrial manufacturing to medicine.
Polyethylene glycol is a polymer with the chemical formula HO (CH2CH2O)nH, non-irritating, slightly bitter taste, good water solubility, and good compatibility with many organic components.


PEG has excellent lubricity, moisturizing, dispersion, adhesion, can be used as an antistatic agent and softener, and has a wide range of applications in cosmetics, pharmaceuticals, chemical fiber, rubber, plastics, papermaking, paint, electroplating, pesticides, metal processing and food processing industries.


-Peg-180 resins are high molecular weight homopolymers of ethylene oxide via heterogeneously catalyzed ring-opening polymerization.
Usually can be divided into the relative molecular mass of 2 × 1 04 above and tens of thousands of above, the former is called polyethylene glycol, the latter is called polyethylene oxide.

Polyethylene oxide with flocculation, thickening, slow release, lubrication, dispersion, retention, water retention and other properties, suitable for medicine, fertilizer, paper, ceramics, detergents, cosmetics, heat treatment, water treatment, fire, oil exploitation and other industries, the product is non-toxic and non-irritating, and will not remain, deposit or breed volatile matter in the process of product generation.

As a papermaking additive, the retention rate of the filler and the fine fiber can be improved, and the dispersant is particularly suitable for the long fiber, and the beating time can be shortened.


-Peg-180 in products:
You can find Peg-180 at:
*cosmetics,
*detergents in tablet form,
*components used in the construction industry,
*packaging production processes,
*processing of plastics and elastomers,
*textile industry processes,
*compounds used for metalworking.


-Medical uses of Peg-180:
*Widely used in pharmaceutical formulations.
*Used as the basis of a number of laxatives.
*Used as an excipient in many pharmaceutical products.
*Possibly used to fuse axons.
*Used to synthetic lubricant.
*Used as solvent to prepare water-soluble drugs.
*Used to modify medical polymer materials.
*Used as linkers for antibody-drug conjugates (ADCs).
*Used as a surface coating on nanoparticles to improve systemic drug delivery.
*Frequently used in many biomedical applications, including but not limited to bioconjugation, drug delivery, surface functionalization and tissue engineering.


-Application of Peg-180:
*body cosmetics (creams, toothpastes, foundations, masks, coloring creams)
*hair cosmetics (sprays, gels, conditioners and dyes)
*preparations used after tanning
*binder for soaps
*fixative for fragrances
*tire production
*additive to flexographic inks
*wood processing


-Peg-180 is a polyethylene glycol that is used for a wide variety of applications including:
*Reactive diol/polyether component in polyester or polyurethene resins
*Component of auxiliaries for leather and textile processing
*Cosmetic / pharmaceutical formulations (e.g. humectant or solubilizer for creams, shampoos, tooth paste)
*Lubricant and mould release agent for rubber, plastic and elastomer processing
*Plasticizer and binder for ceramic and concrete manufacturing
*Component of lubricant formulations
*Water soluble, lubricating component in metalworking fluids
*Humectant for paper, wood and cellulose films
*Solvent and humectant for dyes and inks
*Modifier for production of regenerated viscoses
*Humectant and plasticizer for adhesives.


-Chemical uses of Peg-180:
*Used as lubricating coating for various surfaces.
*Used to create high osmotic pressure.
*Used to passivate microscope slides.
*Used to preserve objects salvaged from underwater.
*Used to preserve the color of painting.
*Used as heat transfer fluid in electronic testers.
*Used as the polar stationary phase of gas chromatography.
*Used as an internal calibration compound in mass spectrometry experiments.


-Biological uses of Peg-180:
*Used as a crowding agent in vitro to simulate highly crowded cellular conditions.
*Used as a precipitant for plasmid DNA isolation and protein crystallization.
*Used for cell fusion.
*Used for virus concentratation.
*Used to coat gene therapy vectors to protect them from inactivation by the immune system.
*Used to package siRNA for in vivo use.
*Used as a potentiator to enhance detection of antigens and antibodies in blood banking.
*Used in the functioning ion channels diameter studies to block ion channel conductance.


-Usage areas of Peg-180:
*Degreasers
mineral oil emulsifier
*Lubricating and antistatic in textile yarn oils
*Pigment printing thickener and emulsifier
*Pigment dispersion
ink organic pigment dispenser
*Pesticide (pesticide, herbicide, fungicide) emulsifier
*Mold release agents
*Metalworking fluids
*Wetting and dispersing in inks and coatings
viscosity adjuster
*In defoamer prescriptions
*Regulator and binder in latex paints
*Dispersant, wetting agent and binder in water and solvent based coatings
*Emulsifier, moisturizer in cosmetic products
*Blend oil emulsifiers


-The kinetic of the ligation in the cloning of DNA-fragments into bacteriophage M13-vectors can be improved by the inclusion of 5% Peg-180.
Especially for the cloning with 'blunt-ended' DNA, the concentration of 'blunt'-DNA-ends plays a crucial role for the successful cloning.
Substances, that increase the so-called 'macromolecular crowding' and condense DNA molecules into aggregates, concentrate the
DNA and increase the possibility, that DNA ends will meet and thereby improve the cloning result.
So, the DNA and enzyme concentration can be reduced.
Besides, such substances reduce the intramolecular ligation (religation).
For 'blunt end' cloning the recommended Polyethylene glycol 8000 concentration is 15%.
Stock solutions of Peg-180 (40%) are prepared with deionized water and stored at -20°C in small aliquots.



MAIN PROPERTIES OF PEG-180:
*Lubricant;
*Smoothing;
*Film Trainer



FUNCTION of PEG-180:
-Binder
-Carrier
-Anti-Static Agent
-Moisturizing Agent
-Humectant
-Plasticizer
-Solvent
-Solubilizer
-Slip Agent
-Viscosity Modifier



FUNCTIONS OF PEG-180 IN COSMETIC PRODUCTS:
*MOISTURIZING:
Peg-180 binds moisture in cosmetic products
*SOLVENT:
Peg-180 brings other substances into solution
*Dispersant
*Wetting Agent
*Moisturizers/Humectants - retain and retain moisture in the skin and hair
*Solvents - they dissolve other substances
*Humectant:
Peg-180 maintains the water content of a cosmetic in its packaging and on the skin
*Solvent:
Peg-180 dissolves other substances



BENEFITS of PEG-180:
-Good solubility in water
-Very low water content
-Compatible with hard water
-Non-volatile
-Outstanding toxicological safety



OCCURRENCE IN COSMETICS, PEG-180:
Peg-180 is used facial, shaving and hair lotions, as solvents and solubilizers for active ingredients, perfume oils and dyes, as humectants, bases for creams, as consistency enhancers, binders, softeners and fixatives



FORMULATIONS WITH PEG-180:
*Hair Care:
Rinse-off Conditioner
The rinse-off conditioner with Peg-180 uses SiW silicone premix technology to delivery a high level of conditioning properties, including excellent feel and shine.
The special anionic silicone blend is added during the cool-down and does not require homogenization.
Comprised of a silicone-in-water emulsion that is easily diluted in all major skin and hair care applications.



GENERAL FEATURES OF PEG-180:
The compound with the INCI name Peg-180 is a surfactant belonging to the polyoxyethylene glycol group.
The CAS number of Peg-180 is 25322-68-3.
Peg-180 is mostly used as an emulsifier in the industry.
Peg-180 also acts as a wetting agent.



WHAT DOES PEG-180 DO IN A FORMULATION?
*Humectant



BENEFITS OF PEG-180:
*safe, non-toxic substance
*unlimited solubility in water
*has hygroscopic properties
*binder
*protects against excessive moisture absorption
*stable in hard water
*it has solubilizing, softening, lubricating and moisturizing properties
*biodegradable



CHARACTERISTIC OF PEG-180:
. Highly compatible to various kinds of organic compounds.
. High boiling point.
. Easy control of the degree of condensation.
. Controllable hygroscopic property.
. Less toxicity, PEG is characterized by less toxicity and less skin irritation.
. There is no damage in case of contact with skin or lips.



THE ROLE AND EFFECTS OF PEG-180:
Peg-180 is primarily an emulsifier for formulations.
Peg-180 efficiently combines the water phase with the oil phase components.
As a surfactant, Peg-180 "positions" itself at the phase boundary and reduces surface tension as it penetrates the phases, so that an emulsion can form.
As a result, a cream, milk or lotion has the right consistency (unbreakable) even though Peg-180 contains ingredients of different chemical nature.



PRODUCT TYPE of PEG-180:
*Humectants
*Plasticizers
*Solvents > Glycols & Glycol Ethers > Ethylene Glycols
*Lubricants / Waxes
*Other Additives for Liquid Systems > Solvents > Glycols
*Plasticizers
*Release Agents



WHAT IS PEG?
Triethylene Glycol and other polyethylene glycols (PEG-4, PEG-6, PEG-7, PEG-8, PEG-9, PEG-10, PEG-12, PEG-14, PEG-16, PEG-18, PEG-20, PEG-32, PEF-33, PEG-40, PEG-45, PEG-55, PEG-60, PEG-75, PEG-80, PEG-90, PEG-100, PEG-135, PEG-150, PEG-180, PEG-200, PEG-220, PEG-240, PEG-350, PEG-400, PEG-500, PEG-800, PEG-2M, PEG-5M, PEG-7M, PEG-9M, PEG-14M, PEG-20M, PEG-23M, PEG-25M, PEG-45M, PEG-65M, PEG-90M, PEG-115M, PEG-160M, PEG-180M) are polymers of ethylene glycol.

The number in the name represents the average number of ethylene glycol units.
The letter associated with the number stands for 1000, so PEG-25M has an average of 25,000 units of ethylene glycol.
Different molecular weight polyethylene glycol has different morphology.

Polyethelene glycol (PEG) is a synthetic, hydrophilic, biocompatible polyether, which is consist of a (−O−CH2−CH2−) backbone.
Its structure is commonly expressed as H−(O−CH2−CH2)n−OH.
Depending on the molecular weight, PEG is also known as polyoxyethylene (POE) or polyethylene oxide (PEO).
PEGs can be synthesized in linear, branched, Y-shaped, or multi-arm geometries.

PEGs can be activated by replaing the terminal hydroxyl end group with various reactive functional end groups enabling crosslinking and conjugation chemistries.
Polyethylene glycol is a polymer with the chemical formula HO (CH2CH2O)nH.



PEG (ETHYLENE GLYCOL) ESTERS:
*PEG 200, PEG 300, PEG 400, PEG 600 Mono and Dioleate
*PEG 200, PEG 300, PEG 400, PEG 600 Mono and dicocoate
*PEG 200, PEG 300, PEG 400, PEG 600 Mono and dilaurate
*PEG 200, PEG 300, PEG 400, PEG 600 Mono and di tall oil fatty acid

Polyethylene glycol esters composed of polyethylene glycol (peg) and fatty acid have various lipophilic-hydrophilic values depending on different peg and fatty acid molecular weights.
Depending on this value, they ensure that water can be emulsified in oil or oil in water.
*Emulsifying oils
*Wetting and lubrication
*Biodegradability
*low toxicity
*not foaming
*Antistatic.



PHYSICAL and CHEMICAL PROPERTIES of PEG-180:
Assay: 95.00 to 100.00 %
Food Chemicals Codex Listed: No
Appearance Form: solid
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available



FIRST AID MEASURES of PEG-180:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of PEG-180:
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of PEG-180:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of PEG-180:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Choose body protection in relation to its type.
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
No special environmental precautions required.



HANDLING and STORAGE of PEG-180:
-Precautions for safe handling:
*Hygiene measures:
General industrial hygiene practice.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage stability:
Recommended storage temperature: 2 - 8 °C



STABILITY and REACTIVITY of PEG-180:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
25322-68-3
CARBOWAX 8000
CARBOWAX PEG 8000
LIPO POLYGLYCOL 8000
LUMULSE PEG 8000
MACROGOL 8000
PEG 8000
PEG-180
PEG-180 [INCI]
POLYETHYLENE GLYCOL 8000 [II]
POLYETHYLENE GLYCOL 8000 [USP-RS]
POLYETHYLENE GLYCOL 8000 [VANDF]
POLYGLYKOL 8000
UPIWAX 8000
PEG
Poly(ethylene glycol)
Polyethyleneglycol 8000
Macrogol 8000
Macrogols 8000
Poly(ethylene glycol)
Polyethyleneglycol 8000
PEG 8k
Polyethylene glycol
Poly(ethylene glycol)
Polyethylene glycol
polyethylene oxide standard 511000
Poly(ethylene oxide)
macrogol
poly(oxyethylene)
Polyethylene glycol PEG
Aquacide III
PEG 1000
PEG 6000, MB Grade (1.12033)
Ethylene glycol 8000 polymer
Polyethyleneglycol
Polyethylene Glycol 5000000
PolyethyleneoxideMW
PEG 200-8000
Tri-(2,3-Dibromopropyl) Phosphate
Polyethylene glycol - 6000 grade
PEG 200
PEG 400
PEG 6000
Poly(ethylene oxide)
PEO
PEG 600
Polyethyleneoxidemonomethacryloxymonotrimethylsiloxyterminated
O-Methacryloxy(polyethyleneoxy)trimethylsilane
PEG
Poly ethylene glycol
Carmowax
carbowax
PEG 8000
Polyethylene glycol series
Polyethylene Glycol
Polyethylene glygcol

PEG-2 Cocamine acts as a non-ionic emulsifier, surfactant and pH regulating agent.
PEG-2 Cocamine is an ethoxylated fatty amine.


CAS Number: 61791-14-8
EC Noumber: 500-152-2
Chem/IUPAC Name: Amines, coco alkyl, ethoxylated (2 mol EO average molar ratio)
INCI name: PEG-2 COCAMINE
Classification: PEG/PPG , Ethoxylated compound , Glycol , Synthetic polymer
Origin(s): Synthetic


SYNONYMS:
(Coconut oil alkyl)amine, ethoxylated, 2-Hydroxyethyl coco amine, ethoxylated, alkyl-amine-n,n-bis(2-omega-hydroxypoly(oxyethylene)ethyl), alkyl-amine-n,n-bis(2-omega-hydroxypoly(oxyethylene)ethyl)(asinfatty, alkyl-amine-n,n-bis(2-omega-hydroxypoly(oxyethylene)ethyl)(asinfattyacidsofcoconut, Amines,cocoalkyl,ethoxylated, Cocoamine polyoxyethylene ether, Cocoamine, ethoxylated, Coconut amine ethoxylate ether (5EO), Ethoxylated cocoamines, Laurylamine ethoxylate ether, PEG-n Cocamine, Polyethylene glycol (n) coconut amine, POLYOXYETHYLENE (10) COCOAMINE, Polyoxyethylene (n) coconut amine, PEG-15 COCAMINE, POLYOXYETHYLENE (10) COCOAMINE, Ethomeen C, Cocoamine polyoxyethylene ether, K 215, GN 8361, PPEM 239, Genamin C, Noramox C, Atmer 169



PEG-2 Cocamine is a chemical compound with the CAS number 61791-14-8.
PEG-2 Cocamine appears as a clear to pale yellow liquid with a characteristic odor.
Its basic structure consists of a cocoamine molecule that has been ethoxylated, meaning PEG-2 Cocamine has undergone a reaction with ethylene oxide to add ethoxy groups to the molecule.


PEG-2 Cocamine is soluble in water and other polar solvents.
PEG-2 Cocamine is an example of a surfactant that acts as a emulsifier for O/W (oil-in-water) emulsions.
Due to its properties, PEG-2 Cocamine is perfect for industrial and institutional cleaning applications, textile processes and automotive chemicals.


PEG-2 Cocamine is a polyethylene glycol derivative of Cocamine (q.v.).
PEG-2 Cocamine acts as a non-ionic emulsifier, surfactant and pH regulating agent.
PEG-2 Cocamine is an ethoxylated fatty amine.


PEG-2 Cocamine is ideal for alkaline emulsions like hair-dye creams or gels.
The compounds vary in polarity depending upon the polyoxyethylene chain length.
HLB of PEG-2 Cocamine is 6.


Typical use level of PEG-2 Cocamine is 1-10%.
Add PEG-2 Cocamine to oil phase of formulas.
PEG-2 Cocamine is a polyethylene glycol derivative of coconut oil alkylamine.



USES and APPLICATIONS of PEG-2 COCAMINE:
PEG-2 Cocamine is commonly used as a latex stabilizer.
PEG-2 Cocamine exhibits very good detergency properties and thus effectively removes solid impurities.
The features of PEG-2 Cocamine are also used by the industrial cleaning branch.


In particular, PEG-2 Cocamine is used in cleaners designed for hard surfaces (industrial and institutional cleaning).
Other products that contain PEG-2 Cocamine include industrial degreasers and cleaners for metal elements.
PEG-2 Cocamine is used industrial cleaning, textile industry, automotive chemicals, degreasers for metals, and hair cosmetics.


In the textile industry processes, PEG-2 Cocamine is used not only as an emulsifier but also as a levelling agent e.g. in the fibre dyeing process.
In microemulsion systems, PEG-2 Cocamine is a co-emulsifier.
The molecular structure of PEG-2 Cocamine determines its cationic character.


Thus PEG-2 Cocamine can form a single layer (film) on the metal surface, which gives it anti-corrosion properties and effectively protects against degradation.
PEG-2 Cocamine is an ingredient used in car cosmetics.


PEG-2 Cocamine is an example of a surfactant that acts as a emulsifier for O/W (oil-in-water) emulsions.
Due to its properties, PEG-2 Cocamine is perfect for industrial and institutional cleaning applications, textile processes and automotive chemicals.
PEG-2 Cocamine, PEG-3 Cocamine, PEG-5 Cocamine, PEG-10 Cocamine, PEG-15 Cocamine and PEG-20 Cocaminerange from viscous liquids to solids.


In cosmetics and personal care products, the PEG Cocamine ingredients are used in the formulation of hair dyes, colors, and tints, hair conditioners, cleansing products, and other hair and skin care products.
PEG-2 Cocamine is used for external use only.
PEG-2 Cocamine is used shampoos, hair and skin care cleansing products and in hair color products to aid the dispersion of dyes and wetting hair fibers.


-Latex Stabilizer uses of PEG-2 Cocamine:
PEG-2 Cocamine is commonly used as a latex stabilizer. Its purpose in this field is to improve the stability and performance of latex products.
The mechanism of action of PEG-2 Cocamine as a latex stabilizer involves its ability to prevent coagulation and improve the dispersion of latex particles, resulting in a more uniform and stable product.



EFFECTS OF PEG-2 COCAMINE IN INDUSTRIAL PRODUCTS:
Effects of PEG-2 Cocamine in industrial products
PEG-2 Cocamine is mainly used in industrial products.
PEG-2 Cocamine works very well in both acidic and alkaline formulations.
PEG-2 Cocamine is also resistant to hard water.
As a surfactant, PEG-2 Cocamine primarily acts as an emulsifiers in products.
As they take a specific position at the phase boundary, molecules of
PEG-2 Cocamine effectively lower the surface tension between the phases and allow for the formation of an emulsion, i.e. a system of two mutually immiscible phases.



WHAT DOES PEG-2 COCAMINE DO IN A FORMULATION?
*Emulsifying



FUNCTIONS OF PEG-2 COCAMINE:
*Emulsifying agent:
PEG-2 Cocamine promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil)



OCCURRENCE OF PEG-2 COCAMINE:
creams, milks, balms,



HOW DOES PEG-2 COCAMINE WORK?
PEG-2 Cocamine is an emulsifier that allows the formation of an emulsion.
PEG-2 Cocamine prevents the separation of cosmetics and allows the oily phase to be combined with the water phase.



FORM THE SCIENTIFIC SIDE OF PEG-2 COCAMINE:
PEG-2 Cocamine is a fatty amine of coconut oil ethoxylated with 2 moles of ethylene oxide.
PEG-2 Cocamine is an ingredient resistant to hard water. Contains calcium and magnesium ions.
PEG-2 Cocamine is sensitive to pH changes and decomposes at acidic pH.



CHARACTERISTICS OF PEG-2 COCAMINE:
PEG-2 Cocamine is an alkyl amine (containing 12 to 18 carbon atoms per molecule) that is ethoxylated with 15 molecules of ethylene oxide.
Due to the presence of a double ethoxylated chain at the nitrogen atom, PEG-2 Cocamine exhibits the activity of both a non-ionic and a cationic surfactant in an application (especially in acidic systems).
The CAS number of PEG-2 Cocamine is 61791-14-8.



FUNCTIONS OF PEG-2 COCAMINE:
*SURFACTANT – EMULSIFIER:
PEG-2 Cocamine helps suspend or disperse liquids in a second liquid by reducing the surface tension of the substances to be emulsified.



PHYSICAL AND CHEMICAL PROPERTIES OF PEG-2 COCAMINE:
*clear liquid (at the room temperature),
*light brown to dark brown colour,
*characteristic odour,
*molar mass: approx. 850 g/mol,
*good solubility in water, ethanol, acetone and ethyl acetate,
*density: approx. 1.02 g/ml (at the temperature of 30ᵒC),
*boiling point: above 200ᵒC (the substance also decomposes above the temperature),
*solidification point: -8ᵒC,
*good resistance to hard water.



FUNCTIONS OF PEG-2 COCAMINE IN COSMETIC PRODUCTS:
Function(s) of this ingredient in cosmetic products
*SURFACTANT - EMULSIFYING
PEG-2 Cocamine allows the formation of finely dispersed mixtures of oil and water (emulsions)



OCCURRENCE IN COSMETICS, PEG-2 COCAMINE:
Face toners, aftershaves and hair tonics, as solvent and solubiliser for active ingredients, perfume oils and colourants, humectants, basis for creams, as consistency enhancer, binding agent, softening agent and fixative
PEG-2 Cocamine is a naturally derived emulsifier for W/O emulsions that is suitable for alkaline emulsions.
PEG-2 Cocamine has an HLB value of about 5.0-7.0, and Natural Origin Index of 0.68.



WHY IS PEG-2 COCAMINE USED?
The PEG Cocamine ingredients help to form emulsions by reducing the surface tension of the substances to be emulsified. They also help other ingredients to dissolve in a solvent in which they would not normally dissolve.



PEG-2 COCAMINE:
Substance information:
"PEG" refers to a PEG-(polyethylene glycol-) derivative.
The number behind "PEG-" (or the first number behind "PEG/...-") refers to the average number of molecular units -CH2-CH2-O-.

"Cocamine" refers to amines of coconut oil (Cocos nucifera oil).
Amines are generally organic compounds which are derived from ammonia and in which one, two or all three hydrogen atoms of the ammonia have been substituted by alkyl or aryl groups.



PHYSICAL and CHEMICAL PROPERTIES of PEG-2 COCAMINE:
CAS Number 61791-14-8
Chem/IUPAC Name: Amines, coco alkyl, ethoxylated (2 mol EO average molar ratio)
EINECS/ELINCS No: 500-152-2
Appearance at 25°C: clear liquid
Color (gardner scale): 11.0 maximum
Neutralization equivalent: 280.0-303.0
Primary & secondary amine: 5.0 maximum
Amine value: 185.0–200.0
Tertiary amine: 95.0 maximum
Moisture content: 1.0 maximum
Refractive index at 25°C: approx. 1.466



FIRST AID MEASURES of PEG-2 COCAMINE:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of PEG-2 COCAMINE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of PEG-2 COCAMINE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of PEG-2 COCAMINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of PEG-2 COCAMINE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of PEG-2 COCAMINE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available

PEG-2 Hydrogenated Tallow Amine is a chemical compound that is often used in cosmetics and personal care products.
PEG-2 Hydrogenated Tallow Amine is a surfactant, which means it helps to mix oil and water-based ingredients, allowing them to blend together more easily.
This makes PEG-2 Hydrogenated Tallow Amine a common ingredient in products like shampoos, conditioners, and skin creams.
The "PEG" in the name stands for polyethylene glycol, which is a polymer that is often used to increase the water solubility of various ingredients.



APPLICATIONS


PEG-2 Hydrogenated Tallow Amine is commonly used in the formulation of shampoos for its emulsifying properties, allowing it to mix water and oil-based ingredients effectively.
PEG-2 Hydrogenated Tallow Amine is often included in hair conditioners to improve their texture and enhance the distribution of conditioning agents.

PEG-2 Hydrogenated Tallow Amine is utilized in body washes and shower gels to create stable and homogeneous formulations.
PEG-2 Hydrogenated Tallow Amine is found in facial cleansers, contributing to their ability to remove makeup and impurities.

PEG-2 Hydrogenated Tallow Amine is used in the manufacture of hand and body lotions to provide a smooth and even application.
Skin creams and moisturizers incorporate this compound for its emollient properties that help maintain skin hydration.
PEG-2 Hydrogenated Tallow Amine is used in shaving creams and gels for its ability to create a creamy and lubricating texture.

PEG-2 Hydrogenated Tallow Amine can be found in baby products such as gentle shampoos and lotions for its mild and non-irritating characteristics.
PEG-2 Hydrogenated Tallow Amine is used in sunscreens to help disperse UV filters evenly, ensuring proper sun protection.

PEG-2 Hydrogenated Tallow Amine is utilized in cosmetics like foundations and BB creams to achieve a smooth and even application on the skin.
In hair styling products like hair gels and mousses, PEG-2 Hydrogenated Tallow Amine assists in providing a consistent texture.
PEG-2 Hydrogenated Tallow Amine is an ingredient in antiperspirants and deodorants, aiding in the even spread of active ingredients.

PEG-2 Hydrogenated Tallow Amine contributes to the texture and spreadability of facial masks and exfoliating scrubs.
Toothpaste formulations may include this compound to enhance the consistency of the product.
In lip balms and lip glosses, it helps maintain a smooth and moisturizing texture.
Some pharmaceutical creams and ointments use PEG-2 Hydrogenated Tallow Amine to create stable, homogenous mixtures.
PEG-2 Hydrogenated Tallow Amine is found in wound care products to ensure uniform application and effectiveness.

PEG-2 Hydrogenated Tallow Amine can be used in veterinary skincare products for animal health.
PEG-2 Hydrogenated Tallow Amine is employed in industrial and household cleaning products as an emulsifying agent.
Lubricating gels and creams, both for personal and industrial use, utilize this chemical for its texture-enhancing properties.
PEG-2 Hydrogenated Tallow Amine may be present in lubricants for machinery and automotive applications.

In the production of printing inks, it assists in maintaining the ink's consistency.
Textile and leather processing industries may use it to aid in the application of treatments and coatings.
PEG-2 Hydrogenated Tallow Amine is utilized in the preparation of certain food products to ensure even mixing of ingredients.
PEG-2 Hydrogenated Tallow Amine's versatility extends to a wide range of industries, making it a valuable ingredient in various formulations.

In the agricultural sector, PEG-2 Hydrogenated Tallow Amine is used in the formulation of pesticides and herbicides to ensure even distribution of active ingredients.
PEG-2 Hydrogenated Tallow Amine can be found in industrial cleaning products and degreasers, aiding in the removal of grease and grime.
PEG-2 Hydrogenated Tallow Amine is used in automotive care products such as car waxes and polishes for consistent application.
PEG-2 Hydrogenated Tallow Amine is employed in the production of printing plates and toners in the graphic arts industry.

PEG-2 Hydrogenated Tallow Amine can be used in the manufacturing of adhesives and sealants to enhance their texture and performance.
PEG-2 Hydrogenated Tallow Amine may be found in the formulation of inks for markers, pens, and stamps.

In the construction industry, it is used in various coatings and sealants for even coverage.
The textile industry uses this compound in the production of fabric softeners to improve their texture and effectiveness.

PEG-2 Hydrogenated Tallow Amine contributes to the even dispersion of pigments in paint and coatings.
PEG-2 Hydrogenated Tallow Amine is used in the production of leather care products such as shoe polishes and leather conditioners.
In the food industry, it is employed in baking and confectionery for consistent mixing of ingredients.
PEG-2 Hydrogenated Tallow Amine can be used in the preparation of flavors and fragrances.

PEG-2 Hydrogenated Tallow Amine is utilized in the formulation of lubricating oils and greases.
PEG-2 Hydrogenated Tallow Amine plays a role in the manufacture of industrial and household detergents and laundry products.
PEG-2 Hydrogenated Tallow Amine contributes to the even distribution of active ingredients in pet care products like shampoos and conditioners.

The pharmaceutical industry uses this compound in various topical creams and ointments.
PEG-2 Hydrogenated Tallow Amine aids in the formulation of industrial coatings and protective finishes.
PEG-2 Hydrogenated Tallow Amine is used in the production of emulsifiable concentrates for agricultural chemicals.

In the electronics industry, it can be found in some cleaning and soldering flux formulations.
PEG-2 Hydrogenated Tallow Amine contributes to the texture and spreadability of industrial and household wax products.
PEG-2 Hydrogenated Tallow Amine can be used in the preparation of cleaning solutions for optical lenses and eyewear.
PEG-2 Hydrogenated Tallow Amine is employed in the production of cleaning and maintenance products for boats and marine equipment.

PEG-2 Hydrogenated Tallow Amine aids in the even dispersion of fragrances in air fresheners and home fragrance products.
PEG-2 Hydrogenated Tallow Amine can be found in the formulation of specialty soaps and hand sanitizers.
PEG-2 Hydrogenated Tallow Amine's applications are diverse and extend to numerous industries, ensuring the effective mixing and distribution of various ingredients in a wide range of products.

PEG-2 Hydrogenated Tallow Amine is used in the formulation of cutting fluids and lubricants for machining operations.
PEG-2 Hydrogenated Tallow Amine can be found in rust inhibitors and corrosion protection products.

PEG-2 Hydrogenated Tallow Amine is employed in the production of specialty candles for a smoother and more even burn.
PEG-2 Hydrogenated Tallow Amine contributes to the texture and performance of mold release agents used in various manufacturing processes.

In the woodworking industry, it is used in the formulation of wood finishes and stains.
PEG-2 Hydrogenated Tallow Amine aids in the dispersion of pigments in artists' paints and art materials.
PEG-2 Hydrogenated Tallow Amine can be used in the production of adhesives and sealants for craft and DIY projects.
PEG-2 Hydrogenated Tallow Amine is found in the formulation of paper coatings to improve their consistency.

PEG-2 Hydrogenated Tallow Amine is utilized in the textile printing industry to create consistent and even patterns on fabrics.
PEG-2 Hydrogenated Tallow Amine can be included in the formulation of paper pulp and papermaking chemicals.

In the rubber and tire industry, it contributes to the mixing of rubber compounds.
PEG-2 Hydrogenated Tallow Amine is used in the formulation of tire shine and tire care products for a uniform finish.

PEG-2 Hydrogenated Tallow Amine plays a role in the production of synthetic and natural rubber latex products.
PEG-2 Hydrogenated Tallow Amine is found in the preparation of lubricants for industrial equipment.
PEG-2 Hydrogenated Tallow Amine is employed in the manufacturing of surfactants and detergents for industrial cleaning applications.

PEG-2 Hydrogenated Tallow Amine is utilized in the formulation of metalworking fluids and coolants.
PEG-2 Hydrogenated Tallow Amine can be found in products for the maintenance and care of industrial machinery.
PEG-2 Hydrogenated Tallow Amine is used in the oil and gas industry for various applications, including drilling and production processes.
The compound is employed in the formulation of hydraulic fluids and brake fluids.
PEG-2 Hydrogenated Tallow Amine contributes to the creation of stable and consistent emulsions in chemical processes.
PEG-2 Hydrogenated Tallow Amine is found in various water treatment and wastewater treatment chemicals.

PEG-2 Hydrogenated Tallow Amine plays a role in the formulation of cleaning products for industrial and institutional use.
PEG-2 Hydrogenated Tallow Amine can be used in the preparation of chemicals for the pulp and paper industry.
PEG-2 Hydrogenated Tallow Amine is employed in the formulation of specialty chemicals for agricultural applications.
The versatile applications of PEG-2 Hydrogenated Tallow Amine extend to many industrial and manufacturing processes, contributing to the uniform distribution of various compounds and substances.

In the petroleum industry, PEG-2 Hydrogenated Tallow Amine is used in drilling mud formulations to aid in the suspension and dispersion of solid particles.
PEG-2 Hydrogenated Tallow Amine can be found in oilfield chemicals used for enhanced oil recovery and well stimulation.

PEG-2 Hydrogenated Tallow Amine is employed in the formulation of fuel additives for improved combustion and fuel stability.
PEG-2 Hydrogenated Tallow Amine contributes to the creation of stable emulsions in the production of food-grade lubricants.
PEG-2 Hydrogenated Tallow Amine is used in the food and beverage industry for mixing and emulsifying ingredients in various recipes.

PEG-2 Hydrogenated Tallow Amine is found in the formulation of food-grade release agents for baking and cooking applications.
PEG-2 Hydrogenated Tallow Amine plays a role in the preparation of edible coatings for fruits and vegetables.
PEG-2 Hydrogenated Tallow Amine is utilized in the production of food-grade preservatives and antimicrobial agents.

In the pharmaceutical industry, it can be found in the formulation of oral and topical drug products.
PEG-2 Hydrogenated Tallow Amine aids in the uniform dispersion of active pharmaceutical ingredients in suspensions and emulsions.
PEG-2 Hydrogenated Tallow Amine is employed in the production of pharmaceutical creams, ointments, and gels.
PEG-2 Hydrogenated Tallow Amine can be included in medical devices and personal care products used in healthcare settings.
PEG-2 Hydrogenated Tallow Amine is found in the preparation of biodegradable and eco-friendly cleaning products.

In the renewable energy sector, the compound contributes to the manufacturing of biodiesel and biofuels.
PEG-2 Hydrogenated Tallow Amine plays a role in the formulation of products for water treatment and purification.
PEG-2 Hydrogenated Tallow Amine can be utilized in the production of sustainable and eco-friendly chemicals.
PEG-2 Hydrogenated Tallow Amine aids in the creation of environmentally friendly pesticides and herbicides.

PEG-2 Hydrogenated Tallow Amine is employed in the development of eco-conscious and biodegradable adhesives.
PEG-2 Hydrogenated Tallow Amine can be used in the production of biodegradable soaps and detergents.
PEG-2 Hydrogenated Tallow Amine is found in the formulation of biodegradable printing inks and coatings.
PEG-2 Hydrogenated Tallow Amine contributes to the development of environmentally friendly and biodegradable personal care products.

In the renewable energy industry, it aids in the manufacturing of sustainable lubricants.
PEG-2 Hydrogenated Tallow Amine is employed in the creation of biodegradable and eco-conscious textile treatments.
PEG-2 Hydrogenated Tallow Amine is found in the formulation of eco-friendly and biodegradable cleaning solutions.
The versatile applications of PEG-2 Hydrogenated Tallow Amine extend to environmentally friendly and sustainable product formulations across various industries.

In the construction industry, PEG-2 Hydrogenated Tallow Amine is used as an additive in concrete formulations to improve workability and reduce water content.
PEG-2 Hydrogenated Tallow Amine is found in the production of sealants and adhesives used in construction projects.
PEG-2 Hydrogenated Tallow Amine contributes to the formulation of asphalt and bitumen emulsions for road construction and maintenance.
PEG-2 Hydrogenated Tallow Amine can be included in the manufacturing of plaster and stucco for smoother application.

PEG-2 Hydrogenated Tallow Amine is employed in the creation of industrial coatings for corrosion protection and surface finishes.
In the wood industry, the compound can be found in wood preservatives and treatments for termite and insect resistance.
PEG-2 Hydrogenated Tallow Amine aids in the formulation of wood adhesives for furniture and cabinetry manufacturing.
PEG-2 Hydrogenated Tallow Amine is used in the paper and pulp industry for sizing and coating paper products.
PEG-2 Hydrogenated Tallow Amine contributes to the production of thermal paper used in receipts and labels.

PEG-2 Hydrogenated Tallow Amine is found in the formulation of inks and dyes for the printing and packaging industry.
PEG-2 Hydrogenated Tallow Amine aids in the development of inkjet and laser printer inks for reliable printing.
PEG-2 Hydrogenated Tallow Amine is used in the production of leather treatments for enhancing texture and durability.

PEG-2 Hydrogenated Tallow Amine can be included in the manufacturing of leather dyes and finishes for various leather goods.
In the textile industry, the compound contributes to the finishing of fabrics for improved color retention and softness.
PEG-2 Hydrogenated Tallow Amine is found in dyeing processes to achieve consistent and even color distribution.
PEG-2 Hydrogenated Tallow Amine is employed in the creation of specialty chemicals used in water treatment and wastewater management.

PEG-2 Hydrogenated Tallow Amine aids in the formulation of flotation agents used in mining and mineral processing.
PEG-2 Hydrogenated Tallow Amine can be found in specialty chemicals for the agrochemical industry, including herbicides and insecticides.
PEG-2 Hydrogenated Tallow Amine contributes to the development of industrial cleaning agents and degreasers for various applications.

PEG-2 Hydrogenated Tallow Amine is used in the formulation of automotive and industrial lubricants.
PEG-2 Hydrogenated Tallow Amine aids in the preparation of metalworking fluids used in machining and manufacturing processes.
PEG-2 Hydrogenated Tallow Amine can be included in the production of chemical solutions for cooling systems and heat exchangers.

PEG-2 Hydrogenated Tallow Amine is found in adhesives used in the assembly of electronic components and devices.
In the aerospace industry, PEG-2 Hydrogenated Tallow Amine plays a role in the manufacturing of specialty coatings and sealants.
The versatile applications of PEG-2 Hydrogenated Tallow Amine encompass a wide array of industries, ensuring the efficient mixing and distribution of components in diverse products and processes.



DESCRIPTION


PEG-2 Hydrogenated Tallow Amine is a chemical compound that is often used in cosmetics and personal care products.
PEG-2 Hydrogenated Tallow Amine is a surfactant, which means it helps to mix oil and water-based ingredients, allowing them to blend together more easily.
This makes PEG-2 Hydrogenated Tallow Amine a common ingredient in products like shampoos, conditioners, and skin creams.

PEG-2 Hydrogenated Tallow Amine is derived from tallow, which is a type of animal fat.
PEG-2 Hydrogenated Tallow Amine is typically treated with hydrogen to make it more stable and less prone to oxidation.
The "PEG" in the name stands for polyethylene glycol, which is a polymer that is often used to increase the water solubility of various ingredients.

PEG-2 Hydrogenated Tallow Amine is a surfactant commonly used in personal care products.
PEG-2 Hydrogenated Tallow Amine plays a crucial role in creating stable emulsions in cosmetic formulations.
PEG-2 Hydrogenated Tallow Amine aids in mixing oil and water-based ingredients.

PEG-2 Hydrogenated Tallow Amine is derived from hydrogenated tallow, a type of animal fat.
PEG-2 Hydrogenated Tallow Amine is a waxy or oily substance.
PEG-2 Hydrogenated Tallow Amine is used in shampoos to help distribute and blend various ingredients.
PEG-2 Hydrogenated Tallow Amine can be found in skin creams, lotions, and hair conditioners.

PEG-2 Hydrogenated Tallow Amine has emulsifying properties, allowing for uniform product texture.
PEG-2 Hydrogenated Tallow Amine can enhance the spreadability of creams and lotions.
PEG-2 Hydrogenated Tallow Amine helps to stabilize the formulation and prevent ingredient separation.
As an emulsifier, it aids in maintaining product consistency.
PEG-2 Hydrogenated Tallow Amine is often used in both rinse-off and leave-on products.

PEG-2 Hydrogenated Tallow Amine is known for its moisturizing and conditioning properties.
PEG-2 Hydrogenated Tallow Amine is typically well-tolerated by the skin.
PEG-2 Hydrogenated Tallow Amine can contribute to the soft and smooth feel of personal care products.
Manufacturers may use various grades of this compound to achieve desired properties.

PEG-2 Hydrogenated Tallow Amine is usually listed in the ingredient list of cosmetics under its full name.
PEG-2 Hydrogenated Tallow Amine may have different CAS and EC numbers based on its specific composition.
The "PEG" component makes it more water-soluble.
PEG-2 Hydrogenated Tallow Amine is often combined with other emollients and thickeners in formulations.

Cosmetic chemists carefully consider its compatibility with other ingredients.
PEG-2 Hydrogenated Tallow Amine assists in the dispersion of fragrances and active ingredients in products.
PEG-2 Hydrogenated Tallow Amine can be found in various skincare and haircare products.
The use of PEG-2 Hydrogenated Tallow Amine is regulated in cosmetics to ensure safety.
PEG-2 Hydrogenated Tallow Amine serves as a versatile and useful ingredient in formulating cosmetic and personal care products.



PROPERTIES


Physical Properties:

Chemical Formula: Varies based on the specific composition.
Appearance: Waxy or oily substance, typically in the form of a white to off-white solid or semi-solid.
Odor: May be odorless or have a mild, characteristic odor.
Solubility: Soluble in water and various organic solvents.
Melting Point/Freezing Point: Typically a range of temperatures due to the mixture's composition.
Density: Varies based on specific grade and composition.
Boiling Point: Varies based on the specific composition.


Chemical Properties:

Emulsifying Agent: PEG-2 Hydrogenated Tallow Amine is used as an emulsifier to facilitate the mixing of oil and water-based substances in various formulations.
Surfactant: It acts as a surface-active agent, reducing the surface tension between different phases in a mixture.
Nonionic: As a nonionic surfactant, it does not carry a net electric charge and is compatible with a wide range of other chemicals.
Hydrophilic-Lipophilic Balance (HLB): The HLB value can vary based on the specific formulation.



FIRST AID


Inhalation (Breathing in the substance):

If PEG-2 Hydrogenated Tallow Amine is inhaled and causes respiratory distress, remove the affected person from the area to a well-ventilated place.
If breathing difficulties persist, seek immediate medical attention.


Skin Contact:

In case of skin contact with PEG-2 Hydrogenated Tallow Amine, promptly remove contaminated clothing and rinse the affected skin with plenty of lukewarm water.
Use a mild soap if available, and gently wash the skin to remove any residual substance.
If irritation, redness, or other adverse skin reactions occur, seek medical advice.


Eye Contact:

If PEG-2 Hydrogenated Tallow Amine comes into contact with the eyes, immediately rinse the affected eye with gently flowing lukewarm water for at least 15 minutes.
Hold the eyelids open to ensure thorough rinsing and remove any contact lenses if present.
Seek medical attention if eye irritation, redness, pain, or vision problems persist.


Ingestion (Swallowing the substance):

If PEG-2 Hydrogenated Tallow Amine is accidentally ingested, do not induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth with water to remove any residual substance.
Seek immediate medical attention and provide the medical personnel with as much information as possible regarding the ingested quantity and any symptoms experienced.


General First Aid Guidelines:

Always prioritize safety and seek medical attention promptly if there is any doubt about the severity of exposure or if adverse symptoms develop.
Do not administer any medications or remedies unless directed by medical professionals.
If providing assistance to someone exposed to PEG-2 Hydrogenated Tallow Amine, ensure your own safety by using appropriate personal protective equipment (PPE) if necessary.
Follow any specific first aid instructions provided on the product's safety data sheet (SDS) or by the manufacturer.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including gloves, protective clothing, safety goggles, and respiratory protection if required, to minimize skin and eye contact, as well as inhalation exposure.

Ventilation:
Use PEG-2 Hydrogenated Tallow Amine in a well-ventilated area to prevent the accumulation of vapors.
Consider using local exhaust ventilation systems or work under a chemical fume hood when handling in enclosed spaces.

Avoid Contact:
Minimize skin contact and avoid eye contact with the substance. In case of contact, follow the first aid measures as previously mentioned.

Hygiene Practices:
Practice good personal hygiene by washing hands and any exposed skin thoroughly after handling PEG-2 Hydrogenated Tallow Amine, especially before eating, drinking, or using the restroom.

No Smoking or Open Flames:
Do not smoke or use open flames near the substance, as it may be flammable under certain conditions.

Avoid Ingestion:
Do not eat, drink, or smoke while handling the substance to prevent accidental ingestion.

Spills and Leaks:
In the event of a spill or leak, follow appropriate spill response procedures.
Use absorbent materials to contain and clean up the spill while wearing protective gear.


Storage:

Storage Area:
Store PEG-2 Hydrogenated Tallow Amine in a cool, dry, and well-ventilated area.
Keep it away from direct sunlight, heat sources, and incompatible materials.

Temperature Control:
Maintain the storage temperature within the recommended range, which may vary depending on the specific product or grade.
Follow manufacturer or supplier recommendations.

Segregation:
Store PEG-2 Hydrogenated Tallow Amine away from incompatible materials, such as strong acids, strong bases, and oxidizing agents.

Containers:
Ensure that containers used for storage are tightly sealed to prevent contamination and to minimize the risk of exposure.
Use containers made of materials compatible with the substance.

Labeling:
Clearly label storage containers with the substance's name, hazards, and any necessary safety information in accordance with regulatory requirements.

Access Control:
Limit access to the storage area to authorized personnel who are familiar with the handling and safety procedures.

Safety Data Sheet (SDS):
Keep a current and readily accessible Safety Data Sheet (SDS) for PEG-2 Hydrogenated Tallow Amine in the storage area for reference.

Compatibility:
Ensure that the storage conditions and containers are compatible with the specific grade or formulation of PEG-2 Hydrogenated Tallow Amine being stored.



SYNONYMS


Polyethylene Glycol-2 Hydrogenated Tallow Amine
PEG-2 Hydrogenated Tallow Amine HCl (if it is a hydrochloride salt form)
Ethoxylated Tallow Amine
Tallow Amine Ethoxylate
Tallow Amine PEG-2
PEG-2 Tallowamine
Ethoxylated Tallow Amine Derivative
Ethoxylated Tallowamine
PEG-2 Oleyl Amine (if the amine source is oleyl instead of tallow)
Tallow Fatty Acid Amine Ethoxylate
PEG-2 Tallow Amine
Polyethylene Glycol (2) Hydrogenated Tallow Amine
PEG-2 Amino Tallow Amine
Ethoxylated Tallow Amine
PEG-2 Tallow Amino Hydrochloride (if in hydrochloride salt form)
Tallow Amine PEG-2 Ether
PEG-2 Tallow Alkyl Amine
Tallow Amine Ethoxylated with 2 Molecules of Ethylene Oxide
Ethoxylated Tallow Primary Amine
PEG-2 Oleyl Tallow Amine (if the amine source includes oleyl and tallow components)
Tallow Amine Ethoxylate Sulfate
PEG-2 Hydrogenated Tallow Fatty Amine
Ethoxylated Fatty Acid Tallow Amine
PEG-2 Aminotallowamide
Ethoxylated Fatty Amine with 2 EO Groups
PEG-2 Tallowamine Acetate
Tallow Amine Polyethylene Glycol Derivative
PEG-2 Tallow Diamine
Tallow Amine Ethylene Oxide Condensate
PEG-2 Hydrogenated Tallow Amine Oleate (if in oleate salt form)
Ethoxylated Tallow Amine Compound
PEG-2 Tallow Amine Phosphate
Tallow Amine Ethoxylated Sulfate
PEG-2 Tallow Amine Stearate (if in stearate salt form)
Ethoxylated Tallow Amine Alkyl Sulfate

PEG-2 Hydrogenated Tallow Amine (Cecajel) refers to a range of non-ionic surfactants derived from animal fats (tallow).
They are a class of polyethoxylated amines (POEAs).
The abbreviation 'POEA' is often erroneously used to refer to PEG-2 Hydrogenated Tallow Amine (Cecajel).

CAS: 61791-26-2
EINECS: 619-169-2

Synonyms
Tallow amine ethoxylate (3-50EO);NE-1808;POEA;ETHOMEEN;PEG-2 HYDROGENATED TALLOW AMINE;trymeentamseries;PEG-5 HYDROGENATED TALLOW AMINE;PEG-8 HYDROGENATED TALLOW AMINE

They are used primarily as emulsifiers and wetting agents for agrochemical formulations, such as pesticides and herbicides (e.g. glyphosate).
PEG-2 Hydrogenated Tallow Amine (Cecajel) is a surfactant and wetting agent that is widely used in various industries such as agriculture, textiles, personal care, and paper production.
PEG-2 Hydrogenated Tallow Amine (Cecajel) is composed of polyoxyethylene (POE) and tallow amine, a type of fatty amine that is derived from animal fats or vegetable oils.
The use of PEG-2 Hydrogenated Tallow Amine (Cecajel) in industrial applications has significantly increased in recent years, due to its unique physical and chemical properties.
PEG-2 Hydrogenated Tallow Amine (Cecajel) is a kind of polymer compound, which contains tallow base primary amine and polyoxyethylene ether group in structure.
PEG-2 Hydrogenated Tallow Amine (Cecajel)'s common chemical structure is R-[(CH2) 7chchch2] n-O(CH2CH2O)mH, where R represents tallow base primary amine, n and m represent the number of oxyethylene ether repeating units.

PEG-2 Hydrogenated Tallow Amine (Cecajel) Chemical Properties
Storage temp.: Room Temperature, under inert atmosphere
Solubility: Chloroform (Slightly), Methanol (Slightly)
Form: Solid
Color: White to Off-White Waxy
EPA Substance Registry System: PEG-2 Hydrogenated Tallow Amine (Cecajel) (61791-26-2)

PEG-2 Hydrogenated Tallow Amine (Cecajel) is a water-soluble and biodegradable compound with an average molecular weight of 522 g/mol.
PEG-2 Hydrogenated Tallow Amine (Cecajel) has a melting point of 36 °C, and its boiling point is 270-280°C.
PEG-2 Hydrogenated Tallow Amine (Cecajel) has a density of 0.91 g/mL and a viscosity of 20 mPas at room temperature.
PEG-2 Hydrogenated Tallow Amine (Cecajel) is stable under normal conditions but can decompose when exposed to high temperatures or acidic and alkaline environments.

Synthesis
Animal fat is hydrolysed to give a mixture of free fatty acids, typically oleic (37–43%), palmitic (24–32%), stearic (20–25%), myristic (3–6%), and linoleic (2–3%).
These are then converted to fatty amines via the nitrile process before being ethoxylated with ethylene oxide; this makes them water-soluble and amphiphilic.
The length of the fatty tail and degree of exothylation will determine the overall properties of the surfactant.
Due to PEG-2 Hydrogenated Tallow Amine (Cecajel) being synthesized from an impure material POEA is itself a mixture of compounds.

Composition and use
The PEG-2 Hydrogenated Tallow Amine (Cecajel) used as a surfactant is referred to in the literature as MON 0139 or polyoxyethyleneamine (POEA).
PEG-2 Hydrogenated Tallow Amine (Cecajel) is contained in the herbicide Roundup.
A PEG-2 Hydrogenated Tallow Amine (Cecajel), is on the United States Environmental Protection Agency List 3 of Inert Ingredients of Pesticides."

PEG-2 Hydrogenated Tallow Amine (Cecajel) is a formulation of glyphosate that contains a "phosphate ester neutralized polyethoxylated tallow amine" surfactant; as of 1997 there was no published information regarding the chemical differences between the surfactant in Roundup and Roundup Pro.
PEG-2 Hydrogenated Tallow Amine (Cecajel) concentrations range from <1% in ready-to-use glyphosate formulations to 21% in concentrates.
PEG-2 Hydrogenated Tallow Amine (Cecajel) constitutes 15% of Roundup formulations and the phosphate ester neutralized polyethoxylated tallow amine surfactant constitutes 14.5% of Roundup Pro.
Surfactants are added to glyphosate to allow effective uptake of water-soluble glyphosate across plant cuticles, which are hydrophobic, and reduces the amount of glyphosate washed off plants by rain.

1. PEG-2 Hydrogenated Tallow Amine (Cecajel) is widely used in personal care products, cleaners and industrial applications.
2. In personal care products, PEG-2 Hydrogenated Tallow Amine (Cecajel) is often used as a component of shampoo, shower gel, conditioner, etc., which can increase the consistency of the product and improve its lubricity and foaming.
3. In the detergent, PEG-2 Hydrogenated Tallow Amine (Cecajel) is commonly used in the preparation of detergents to improve the adhesion and detergency of detergents.
4. In the industrial field, PEG-2 Hydrogenated Tallow Amine (Cecajel) is also used as a pickling agent, an anti-precipitation agent, an antistatic agent, etc.

Environmental effects
The chemical complexity of PEG-2 Hydrogenated Tallow Amine (Cecajel) makes it difficult to study in the environment.
PEG-2 Hydrogenated Tallow Amine (Cecajel) is toxic to aquatic species like fish and amphibians. Like other surfactants, it can affect membrane transport and can often act as a general narcotic.
In laboratory experiments PEG-2 Hydrogenated Tallow Amine (Cecajel) has a half-life in soils of less than 7 days.
Washout from soil is assumed to be minimal, and the estimated half-life in bodies of water would be about 2 weeks.
Field experiments have shown that the half-life of PEG-2 Hydrogenated Tallow Amine (Cecajel) in shallow waters is about 13 hours, "further supporting the concept that any potential direct effects of formulated products on organisms in natural waters are likely to occur very shortly post-treatment rather than as a result of chronic or delayed toxicity."

A review of the literature provided to the EPA in 1997 found that PEG-2 Hydrogenated Tallow Amine (Cecajel) was generally more potent in causing toxicity to aquatic organisms than glyphosate, and that POEA becomes more potent in more alkaline environments.
(Potency is measured by the median lethal dose (LD50); a low LD50 means that just a little of the substance is lethal; a high LD50 means that it takes a high dose to kill.)
Glyphosate has an LD50 ranging from 4.2 times that of PEG-2 Hydrogenated Tallow Amine (Cecajel) for midge larvae at pH 6.5, to 369 times that of POEA for rainbow trout at pH 9.5 (for comparison, at pH 6.5 the LC50 of glyphosate was 70 times that of POEA for rainbow trout).
The pH value of most freshwater streams and lakes is between 6.0 and 9.0; fish species are harmed by water having a pH value outside of this range.

Preparation Method
PEG-2 Hydrogenated Tallow Amine (Cecajel) can be prepared by reacting tallow-based primary amine with ethylene oxide.
A specific preparation method involves introducing an oxyethylene molecule into a tallow primary amine molecule and polymerizing PEG-2 Hydrogenated Tallow Amine (Cecajel) to form a polymer.

PEG-20 CASTOR OIL, N° CAS : 61791-12-6, Origine(s) : Synthétique. Nom INCI : PEG-20 CASTOR OIL. Castor oil, ethoxylated; polyethyleneglycol ester of castor oil; 20 moles ethoxylated; Polyoxyl 20 castor oill, Polymère de synthèse.Ses fonctions (INCI). Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile). Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation. Noms français : Huile de castor éthoxylée. Noms anglais :CASTOR OIL, ETHOXYLATED; ETHOXYLATED CASTOR OIL. Utilisation et sources d'émission: Agent antimousse, lubrifiant. Castor oil, ethoxylated; polyethyleneglycol ester of castor oil; 20 moles ethoxylated; Polyoxyl 20 castor oil

PEG-20 is condensation polymers of ethylene oxide and water with the general formula H(OCH2CH2)nOH.
They are the most commercially important type of polyether.
The low molecular weight compounds up to 700 are colorless, odorless viscous liquids with a freezing point from -10˚C (diethylene gycol), while polymerized compounds with higher molecular weight than 1,000 are wax like solids with melting point up to 67˚C.

CAS: 25322-68-3
MF: N/A
EINECS: 500-038-2

While PEG-20 with different molecular weights find use in different applications and have different physical properties (e.g. viscosity) due to chain length effects, their chemical properties are nearly identical.
The numbers that are often included in the names of PEG-20 indicate their average molecular weights, e.g. a PEG with n=9 would have an average molecular weight of approximately 400 and would be labeled PEG 400.
Most PEG-20 include molecules with a distribution of molecular weights, i.e. they are polydisperse.

PEG-20 is soluble in water and most organic solvents.
PEG-20 is non-toxic, odorless, neutral, lubricating, nonvolatile and nonirritating and are used in a variety of pharmaceuticals and in medications as a solvent, dispersing agent, ointment and suppository bases, vehicle, and tablet excipient.
Any of several condensa-tion polymers of ethylene glycol with thegeneral formula HOCH2(CH2OCH2)nCH2OH orH(OCH2CH2)nOH.

Average molecular weightsrange from 200 to 6000.
Properties vary with molec-ular weight.
PEG-20 is a polyethylene Glycol is a polymer with a high affinity for water.
When used at the proper concentration it can remove proteins from water.
Generally the larger the protein the less PEG-20 needed.
Higher PEG polymers, PEG 4000-6000, have been used for DNA precipitation and even higher polymers, PEG 8000, can be used to precipitate DNA.
PEG-20 has also been used to recover pathogenic viruses and human rotaviruses from water, oyster and sediment samples.
PEG-20 has demonstrated to have anticell proliferation and antitumor effects via induction of apoptosis.

PEG-20 Chemical Properties
Melting point: 64-66 °C
Boiling point: >250°C
Density: 1.27 g/mL at 25 °C
Vapor density: >1 (vs air)
Vapor pressure: Refractive index: n20/D 1.469
Fp: 270 °C
Storage temp.: 2-8°C
Solubility H2O: 50 mg/mL, clear, colorless
Form: waxy solid
Color: White to very pale yellow
Specific Gravity: 1.128
PH: 5.5-7.0 (25℃, 50mg/mL in H2O)
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
λmax: λ: 260 nm Amax: 0.6
λ: 280 nm Amax: 0.3
Merck: 14,7568
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: -0.698 at 25℃
NIST Chemistry Reference: PEG-20 (25322-68-3)
EPA Substance Registry System: PEG-20 (25322-68-3)

Uses
PEG-20 molecules of approximately 2000 monomers.
PEG-20 is used in various applications from industrial chemistry to biological chemistry.
Recent research has shown PEG-20 maintains the ability to aid the spinal cord injury recovery process, helping the nerve impulse conduction process in animals.
In rats, PEG-20 has been shown to aid in the repair of severed sciatic axons, helping with nerve damage recovery.
PEG-20 is industrially produced as a lubricating substance for various surfaces to reduce friction.
PEG-20 is also used in the preparation of vesicle transport systems in with application towards diagnostic procedures or drug delivery methods.

Biological uses
PEG-20 can be modified and crosslinked into a hydrogel and used to mimic the extracellular matrix (ECM) environment for cell encapsulation and studies.
An example study was done using PEG-20-diacrylate hydrogels to recreate vascular environments with the encapsulation of endothelial cells and macrophages.
This model furthered vascular disease modeling and isolated macrophage phenotype's effect on blood vessels.
PEG-20 is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.

PEG-20 is commonly used as a precipitant for plasmid DNA isolation and protein crystallization.
X-ray diffraction of protein crystals can reveal the atomic structure of the proteins.
PEG-20 is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas.
Polymer segments derived from PEG-20 polyols impart flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam cushions.

In microbiology, PEG-20 precipitation is used to concentrate viruses.
PEG-20 is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro.
Gene therapy vectors (such as viruses) can be PEG-20-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect.
The size of the PEG-20 polymer has been shown to be important, with larger polymers achieving the best immune protection.
PEG-20 is a component of stable nucleic acid lipid particles (SNALPs) used to package siRNA for use in vivo.

In blood banking, PEG-20 is used as a potentiator to enhance detection of antigens and antibodies.
When working with phenol in a laboratory situation, PEG-20 can be used on phenol skin burns to deactivate any residual phenol.
In biophysics, PEG-20 is the molecules of choice for the functioning ion channels diameter studies, because in aqueous solutions they have a spherical shape and can block ion channel conductance.

Production Methods
PEG-20 polymers are formed by the reaction of ethylene oxide and water under pressure in the presence of a catalyst.

Reactivity Profile
PEG-20 is heat-stable and inert to many chemical agents; Poly(ethylene glycol) will not hydrolyze or deteriorate under normal conditions.
PEG-20 has a solvent action on some plastics.

Synonyms
1,2-ethanediol,homopolymer
2-ethanediyl),.alpha.-hydro-.omega.-hydroxy-Poly(oxy-1)
Alcox E 160
Alcox E 30
alcoxe30
Poly(ethylene oxide),approx. M.W. 600,000
Poly(ethylene oxide),approx. M.W. 200,000
Poly(ethylene oxide),approx. M.W. 900,000

ethane-1,2-diol;propane-1,2,3-triol (peg-20); poly(oxy-1,2-ethanediyl); '-1,2,3-propanetriyltris-.omega.-hydroxy-; monooctadecanoate (20 mol EO average molar ratio); polyethylene glycol (20) glyceryl stearate; polyoxyethylene (20) glyceryl stearate cas no: 51158-08-8

PEG-20 Stearate is a polyethylene glycol ester of stearic acid.
Peg-20 Stearate is a cream-colored soft, waxy, or pasty solid with a faint fatty odor.


CAS Number: 9004-99-3 / 111-60-4 / 86418-55-5
EC Number: 203-886-9 / 617-851-4 / 618-405-1 / 926-608-4
Chem/IUPAC Name: 2-hydroxyethyl octadecanoate
Origin(s): Synthetic
INCI name: PEG-20 STEARATE
Classification: PEG / PPG, Ethoxylated compound, Glycol, Synthetic polymer
Chemical Formula: C20H42O2



Poly(oxy-1, 2-ethanediyl), α-(1-oxooctadecyl)-ω-hydroxy-, Glycols, polyethylene, monostearate, Stearic acid, monoester with polyethylene glycol, Nonex 28, Nonex 29, PEG 42, Myrj 45, Myrj 49, Myrj 51, Myrj 52, Myrj 53, Nonex 53, Nonex 54, Nonex 63, X 489R, S 541, S 1012, S 1054, S 1116, Atlox 5000, Cerasynt M, Cerasynt MN, Cithrol PS, Clearate G, Crill 20, Emcol H 35A, Empilan CP 100, Empilan CQ 100, Kessco X 211, Lactine, Lipal 15S, Macrogol stearate 400, PEG 600 monostearate, PEG 1000 monostearate, Perphinol 45/100, Polyethylene glycol 200 monostearate, Polyethylene glycol 4000 monostearate, Polyethylene glycol 300 monostearate, Polyethylene glycol monostearate, Polyethylene glycol 400 monostearate, Polyethylene glycol 400 stearate, Polyethylene glycol 1540 stearate, Polyethylene glycol 3000 monostearate, Polystate, Prodhybase P, Prodhybase 4000, Soromin SG, Stabilisant Delta 118, Ethofat 60/25, Polystate B, Poly(oxyethylene) stearate, Polyethylene glycol stearate, Myrj 52S, Stearox 6, Myrj, Myrj 59, Nikkol MYS 45, PEG stearate, Stearic acid-ethylene oxide adduct, Ethofat 60/20, Ethofat 60/15, Polyethylene oxide monostearate, S 1004, S 1016, S 1042, Carbowax 1000 monostearate, Carbowax 1500 monostearate, Poly(ethyleneoxy)monostearate, Poly(oxyethylene) monostearate, Nonion S 15, Polyethylene glycol 40 monostearate, LX 3, Poly(oxyethylene) stearic acid ester, PEG 600MS, PEG 100MS, PEG 1000MS, Cithrol 10MS, Nissan Nonion S 15, Emery 15393, Nikkol MYS 40, 8035-96-9, 8050-55-3, 9009-90-9, 11107-94-1, 11108-48-8, 35885-17-7, 39404-30-3, 42610-76-4, 52504-21-9, 52504-22-0, 52504-23-1, 53228-13-0, 53335-42-5, 55247-85-3, 58375-39-6, 63654-37-5, 72993-78-3, 74870-86-3, 86473-52-1, 121340-91-8, 123543-87-3, 939018-14-1, 1436689-96-1, 1887122-60-2, 1887123-58-1, 2143941-58-4, PEG-20 Glyceryl Stearate, Stearic Acid, Glycerol Ester, ethoxylated (on average 20 units of -CH2-CH2-O-), PEG-20 Stearate, MACROGOL 1000 STEARATE, NBX892EA57, PEG-20 STEARATE (II), POLYETHYLENE GLYCOL 1000 STEARATE, POLYOXYL 20 STEARATE, PEG 20 Stearate, Protamate 1000-DPS, Lumulse 100-S, Jeemate 1000-DPS, Polyethylene Glycol 20 Stearate, PEG-20 Stearate (INCI), Polyethylene Glycol 1000 Monostearate, Polyethylene Glycol Stearate, Polyoxyethylene (20) Monostearate1, 2-EICOSANEDIOL, Icosane-1, 2-diol, 39825-93-9, ARACHIDYL GLYCOL, eicosane-1, 2-diol, L26F8X2O47, 1, 2-icosanediol, 1, 2-Dihydroxy-eicosane, EINECS 254-647-0, UNII-L26F8X2O47, 1, 2-dihydroxyicosane, 1, 2-dihydroxyeicosane, SCHEMBL440727, ARACHIDYL GLYCOL [INCI], CHEBI:84957, DTXSID70960389, KUWCMTFKTVOJID-UHFFFAOYSA-N, LMFA05000076, FT-0667828, Q27158219,



Peg-20 Stearate is manufactured by the polymerization of ethylene oxide (EO) with water, monoethylene glycol or diethylene glycol, under alkaline conditions.
Peg-20 Stearate is the polyethylene glycol ester of stearic acid


Peg-20 Stearate is a cream-colored soft, waxy, or pasty solid with a faint fatty odor.
Peg-20 Stearate is a soft-waxy solid used in cosmetics and personal care products such as skin creams, conditioners, shampoos, body cleansers and soapless detergents.


Peg-20 Stearate is a hydroxypolyether and an octadecanoate ester.
Peg-20 Stearate functions as an emulsifier, cleanser, non-ionic surfactant, and a moisturizer.
Peg-20 Stearate is a blend of cetearyl alcohol and PEG-20 stearate, supplied in pellet form.


Peg-20 Stearate is non-ionic so it is compatible with a wide range of ingredients.
Peg-20 Stearate is a self thickening non-ionic emulsified wax with HLB value of about 8, resistant to acid and alkali.
Peg-20 Stearate can emulsify both polar and nonpolar molecules.


With the good spreadability and easy application, Peg-20 Stearate can improve the absorption of functional ingredients.
Peg-20 Stearate has a unique microcrystalline structure and is nearly tasteless hydrophilic and lipophilic.
Peg-20 Stearate acts as a solid non-ionic primary emulsifier, co-emulsifier, solubilizer, stabilizing agent and viscosity modifier.


"PEG" refers to a PEG-(polyethylene glycol-) derivative.
The number behind "PEG-" (or the first number behind "PEG/...-") refers to the average number of molecular units -CH2-CH2-O-.
Stearates are salts or esters of stearic acid (octadecanoic acid).



USES and APPLICATIONS of PEG-20 STEARATE:
Occurrence of Peg-20 Stearate in cosmetics: Face toners, aftershaves and hair tonics, as solvent and solubiliser for active ingredients, perfume oils and colourants, humectants, basis for creams, as consistency enhancer, binding agent, softening agent and fixative
Peg-20 Stearate is used cosmetics, personal care, hair care, pharmaceutical emulsifier


Peg-20 Stearate is used in preparation of fatty alcohol ethoxylates via etherification of fatty alcohol with ethylene glycol.
Peg-20 Stearate is used in skincare anti-aging, skincare anti-acne, skincare treatment.
Saponification value of Peg-20 Stearate is 39-49


Recommended use level of Peg-20 Stearate is 1-5%.
Peg-20 Stearate is used for external use only.
Peg-20 Stearate is used emulsions for skin and hair care products.


Peg-20 Stearate works as an emulsifier, cleanser, surfactant, and a moisturizer in cosmetics and personal care products.
Peg-20 Stearate also functions as a lubricant and antistatic agent.
Peg-20 Stearate is used in dentifrices, creams, lotions, ointments, etc.
Peg-20 Stearate can be used as an ideal emulsifier for cosmetics and hair products, especially for emulsifying oils and waxes or dispersing powders.



FUNCTIONS OF PEG-20 STEARATE:
*Emulsifier,
*Solubilizer,
*Surfactant (Nonionic),
*Surfactant



ORIGIN OF PEG-20 STEARATE:
*Vegetable Origin,
*Synthetic,
*Oleochemical



LABELING CLAIMS OF PEG-20 STEARATE:
*BSE-free,
*Ulta Beauty's Conscious Beauty,
*TSE-free,
*Non-GMO



SKIN CARE USES OF PEG-20 STEARATE:
Peg-20 Stearate cleans the skin by helping water to mix with oil and dirt so that they can be rinsed away.
Peg-20 Stearate is also used as a lubricant to make creams, lotions and ointments.

Peg-20 Stearate is used in sunscreen products as a moisturizing base. Peg-20 Stearate is used in shaving creams, hand creams, face makeup, bath products, etc.
Peg-20 Stearate is used at a concentration of >1% in skincare products, hair dyes, moisturizers, and styling gels



WHAT DOES PEG-20 STEARATE DO IN A FORMULATION?
*Emulsifying
*Surfactant



ALTERNATIVES OF PEG-20 STEARATE:
*COCOGLUCOSIDE,
*LAURYL GLUCOSIDE,
*SUCROSE COCOATE



FUNCTIONS OF PEG-20 STEARATE IN COSMETIC PRODUCTS:
*SURFACTANT - EMULSIFYING:
Peg-20 Stearate allows the formation of finely dispersed mixtures of oil and water (emulsions)



FUNCTIONS OF PEG-20 STEARATE:
*Emulsifying :
Peg-20 Stearate promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil)
*Humectant :
Peg-20 Stearate maintains water content of a cosmetic both in its packaging and on the skin
*Surfactant :
Peg-20 Stearate reduces the surface tension of cosmetics and contributes to the even distribution of the product when it is used



FUNCTIONS OF PEG-20 STEARATE:
1. Anti-foaming Agent / Defoamer:
Peg-20 Stearate reduces or hinders the formation of foam.

2. Binder / Stabilizer:
Peg-20 Stearate retains the physical characteristics of food/cosmetics and ensure the mixture remains in an even state.

3. Emulsifier:
Peg-20 Stearate allows water and oils to remain mixed together to form an emulsion.

4. Surfactant:
Peg-20 Stearate reduces the surface tension to allow mixtures to be formed evenly.
Emulsifier is a specific type of surfactant which allows two liquids to mix together evenly
Peg-20 Stearate is an ester of Stearic Acid (a naturally occurring fatty acid).

Peg-20 Stearate is also referred to as Polyoxyethylene Stearate.
Polyethylene Glycol is made from Ethylene Glycol monomers.
Peg-20 Stearate then reacts with Stearic Acid to form Polyethylene Glycol Stearate.

As a food additive, Peg-20 Stearate has E number 431.
Peg-20 Stearate can be found in bread to give a soft texture and may also be found in some wines.
Peg-20 Stearate is approved to use as food additive in EU.



FUNCTIONAL GROUP OF PEG-20 STEARATE:
*Base ingredients
*Active ingredients
*Preservatives
*UV filters
*Dyes
*Fragrances



FEATURE OF PEG-20 STEARATE:
*O/W emulsifier, an ingredient enabling the creation of an emulsion.
*Peg-20 Stearate is an emulsion is a physicochemical form that is created by combining (mixing) the water phase with the oil phase.
Examples of cosmetic emulsions are creams, milks and balms.
*Peg-20 Stearate is a foam-forming substance that stabilizes and improves foam quality in a mixture with anionic surfactants.
*Peg-20 Stearate acts as a rheology modifier (i.e. improves consistency, increasing viscosity) in washing preparations containing anionic surfactants, thanks to the creation of the so-called mixed micelles.



FUNCTION OF PEG-20 STEARATE:
Peg-20 Stearate is an emulsifier for oil-in-water creams and lotions.
Peg-20 Stearate increases viscosity and stability in creams and lotions.



MARKET OF PEG-20 STEARATE:
The Peg-20 Stearate Market centers around the production, distribution, and application of PEG-20 stearate, a versatile chemical compound commonly used in the formulation of cosmetics, personal care products, and pharmaceuticals.
Peg-20 Stearate is a polyethylene glycol ester of stearic acid, known for its emulsifying and surfactant properties.

Peg-20 Stearate acts as an effective stabilizer in formulations, facilitating the mixing of water and oil-based ingredients, and imparting a smooth and creamy texture to various skincare and cosmetic products.
Peg-20 Stearate finds extensive use in the beauty and pharmaceutical industries, contributing to the creation of stable and well-textured formulations that enhance the overall sensory experience for consumers.

Growth drivers for the Peg-20 Stearate Market include the expanding cosmetic and personal care industry, the demand for multifunctional ingredients, and the increasing focus on skincare formulations.
As consumers become more conscious of the ingredients in their skincare products, there is a growing preference for formulations that offer stability, texture enhancement, and compatibility with various ingredients.

Peg-20 Stearate addresses these demands by serving as a versatile emulsifier and stabilizer, contributing to the growth of innovative and effective skincare and cosmetic products.
The market's trajectory is further influenced by the continuous evolution of formulations in the beauty and pharmaceutical sectors, with Peg-20 Stearate playing a crucial role in meeting the dynamic requirements of modern skincare and cosmetic applications.



WHAT IS PEG?
Polyethylene Glycol (PEG) Stearates (PEG-2 Stearate, PEG-6 Stearate, PEG-8 Stearate, PEG-12 Stearate, PEG-20 Stearate, PEG-32 Stearate, PEG-40 Stearate, PEG-50 Stearate, PEG-100 Stearate, PEG-150 Stearate) are esters of polyethylene glycol and stearic acid.
The PEG Stearates are soft to waxy solids that are white to tan in color. In cosmetics and personal care products, PEG Stearates are used in skin creams, conditioners, shampoos, body cleansers and soapless detergents.



WHY IS PEG USED?
The PEG Stearates clean the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away.



SCIENTIFIC FACTS OF PEG:
The PEG Stearates are produced from stearic acid, a naturally occurring fatty acid
A natural organic compound that consists of a carboxyl group (oxygen, carbon and hydrogen) attached to a chain of carbon atoms with their associated hydrogen atoms.

The chain of carbon atoms may be connected with single bonds, making a ‘saturated’ fat; or it may contain some double bonds, making an ‘unsaturated’ fat.
The number of carbon and hydrogen atoms in the chain is what determines the qualities of that particular fatty acid.
Animal and vegetable fats are made up of various combinations of fatty acids (in sets of three) connected to a glycerol molecule, making them triglycerides.

The numerical value of each PEG Stearate corresponds to the average number of ethylene oxide monomers in the polyethylene chain.
Polyethylene glycol ingredients may also be named with a number that indicates molecular weight, for example polyethylene glycol (400) stearate is another name for PEG-8 Stearate.



PHYSICAL and CHEMICAL PROPERTIES of PEG-20 STEARATE:
PSA: 46.53000
XLogP3: 5.78340
Appearance: Liquid
Density: 0.913g/cm3
Melting Point: 41 °C
Boiling Point: 438.4ºC at 760mmHg
Flash Point: 39ºC
Refractive Index: 1.457
Water Solubility: SOL IN TOLUENE, ACETONE, ETHER AND ETHANOL
Storage Conditions: Keep tightly closed in a cool place in a tightly closed container.
Toxicity: LD50 oral in rabbit: > 12mL/kg
Odor: FAINT FATTY ODOR
CAS No.: 9004-99-3
Molecular Formula: (C2H4O)nC18H36O2
InChIKeys: InChIKey=RFVNOJDQRGSOEL-UHFFFAOYSA-N

Molecular Weight: 328.53000
Exact Mass: 328.29800
EC Number: 926-608-4
HScode: 3907200000
Categories: Emulsifier
PSA: 46.53000
XLogP3: 5.78340
Appearance: Liquid
Density: 0.913g/cm3
Melting Point: 41 °C
Boiling Point: 438.4ºC at 760mmHg
Flash Point: 39ºC
Refractive Index: 1.457
Water Solubility: SOL IN TOLUENE, ACETONE, ETHER AND ETHANOL
Storage Conditions: Keep tightly closed in a cool place in a tightly closed container.
Odor: FAINT FATTY ODOR

Boiling Point: 438-439°C
Melting Point: 30-34°C
Solubility: Soluble in water, ethanol, methanol
Origin: Synthetic
Shelf life: 2 years from mfg. date
Freight Classification: NMFC 48580 SUB 3 CLASS 55
Kosher Status: Not Kosher
Flash Point: 39 øC
Melting Point: 47 øC
API: NO
Allergen: NO
Hazmat: YES
Molecular Weight: N/A
CAS No.: 9004-99-3
Formula: C34h70o9
EINECS: 618-405-1
Usage: Surfactants

Color: White
INCI Name: Polyoxyethylene Stearate/ CETEARYL ALCOHOL
Appearance: White to yellowish solid
Acid Value(mg KOH/g): ≤1.0
Sapon Value(mg KOH/g):≤15.0
Molecular Weight: 314.5 g/mol
XLogP3-AA: 8.3
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 18
Exact Mass: 314.318480578 g/mol
Monoisotopic Mass: 314.318480578 g/mol
Topological Polar Surface Area: 40.5Ų
Heavy Atom Count: 22
Formal Charge: 0
Complexity: 194

Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Melting point: 48-53 °C
Boiling point: 413.1±18.0 °C(Predicted)
Density: 0.867±0.06 g/cm3(Predicted)
Flash point: 100 °C
storage temp.: 2-8°C
solubility: Chloroform (Sparingly), Ethyl Acetate (Slightly)
pka: 14.42±0.10(Predicted)
form: Solid
color: White to Off-White



FIRST AID MEASURES of PEG-20 STEARATE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of PEG-20 STEARATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of PEG-20 STEARATE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of PEG-20 STEARATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of PEG-20 STEARATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
*Storage stability:
Recommended storage temperature: 2 - 8 °C



STABILITY and REACTIVITY of PEG-20 STEARATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available