Paint, Construction, Plastics, Rubber Chemicals

MONOMULS 90-L
Monomuls 90-L also provides our bodies with a great boost that helps us get the upper hand on long-term infections like Epstein-Barr virus.
Monomuls 90-L is chemical formula is C15H30O4.
Monomuls 90-L is a chemical made from lauric acid, which is found in coconut oil and human breast milk.

CAS Number: 142-18-7
Molecular Formula: C15H30O4
Molecular Weight: 274.4
EINECS Number: 205-526-6

Monomuls 90-L is a very safe nutritional way to fight off infections that may arise during the cold/flu season.
Most common hospital and foodborne infections have become resistant to the effects of traditional antibiotics, and people are dying of formerly treatable conditions.
Monomuls 90-L is derived from lauric acid, a medium-chain saturated fatty acid found in coconut oil.

Monomuls 90-L has antimicrobial, antiviral, and antibacterial properties.
In nature, Monomuls 90-L is a precursor to Monomuls 90-L, which is an even more powerful antimicrobial agent than lauric acid.
Monomuls 90-L has been shown in research to treat Candida albicans infections, whilst also controlling the pro-inflammatory response of the body to the fungus.

Several species of ringworm and the parasite Giardia lamblia may also be inactivated or destroyed by Monomuls 90-L.
Monomuls 90-L is a monoester formed from glycerol and the saturated fatty acid lauric acid.
Monomuls 90-L is also commonly referred to by its chemical name glycerol monolaurate (GML).

Both lauric acid and the monoester Monomuls 90-L are found in coconut oil, human breast milk and palm kernel oil.
Monomuls 90-L is possible for the body to convert lauric acid into Monomuls 90-L via enzyme activity, but how much this conversion process occurs is still fairly unknown.
Monomuls 90-L is pure sn-1 Monomuls 90-L (glycerol monolaurate) a natural, plant-based medium chain fat derived from lauric acid.

The same Monomuls 90-L received from mother’s milk, saw palmetto, and bitter melon – embraced by both immune system and your digestive tract.
Monomuls 90-L is a dietary supplement derived from lauric acid, a fatty acid found in coconut oil.
Monomuls 90-L is used for the common cold, flu (influenza), shingles (herpes zoster), and other infections, but there is no good scientific evidence to support its use.

Monomuls 90-L is a chemical derived from lauric acid and glycerin, and is a byproduct of coconut fat.
For the past two decades, research scientists have been investigating possible applications for Monomuls 90-L in medicine, sanitization, and food preservation.
Antibiotic resistance has become a worldwide problem.

Monomuls 90-L is a chemical made from lauric acid, which is found in coconut milk and breast milk.
Monomuls 90-L is a compound derived from lauric acid, a medium-chain fatty acid found in coconut oil and breast milk.
Monomuls 90-L is used to support immune health and may help to reduce inflammation.

Monomuls 90-L is derived from lauric acid and glycerin, and is a byproduct of coconut fat.
Monomuls 90-L also occurs naturally in breast milk.
Monomuls 90-L is an organic compound made from lauric acid.

Monomuls 90-L is chemical formula is C15H30O4.
Other names for Monomuls 90-L include glycerol monolaurate, glyceryl laurate or 1-lauroyl-glycerol.
Monomuls 90-L is a 1-monoglyceride and a dodecanoate ester.

Monomuls 90-L (abbreviated GML; also called glycerol monolaurate, glyceryl laurate, and 1-lauroyl-glycerol) is a monoglyceride.
Monomuls 90-L is known for its antimicrobial properties, and Monomuls 90-L is created by glycerolysis, a process that removes the glycerol molecule from lauric acid.
Monomuls 90-L is an encapsulated formula of Monomuls 90-L (glycerol monolaurate), a form of lauric acid, which is the predominant fatty acid in coconut and palm kernel oils and is also present
in human breast milk.

Monomuls 90-L also contains Vitamin C for added immune benefit.
Monomuls 90-L is a component of coconut oil.
Monomuls 90-L increases their immune response, making them more resilient to bacterial, viral and fungal infections.

Monomuls 90-L is a naturally-occurring fat present in both coconut oil and breast milk.
Monomuls 90-L is a dietary supplement derived from lauric acid - a medium chain fatty acrid present in coconut and palm oil.
Existing research explores Monomuls 90-L’s potential to exhibit antiviral, antibacterial, and antifungal properties in controlled laboratory studies.

The literature review below explores some of these studies, their results, and potential impact on supporting a healthy immune system.
Also known as glycerol monolaurate or glyceryl laurate, Monomuls 90-L is used in cosmetics and as a food additive.
Monomuls 90-L has shown antibacterial and antiviral effects when examined in test tubes and culture dishes, which is referred to as in vitro testing.

Researchers are currently investigating its usefulness in clinical settings.
This article looks at the potential benefits and side effects of Monomuls 90-L.
Monomuls 90-L is a natural plant-based medium chain fatty acid derived from lauric acid.

Monomuls 90-L is the same Monomuls 90-L that exists in mother’s milk and that supports immune system and digestive health.
Monomuls 90-L is all natural and free from any potential drug interactions or coconut allergens.
To be taken for long-term support and general health and wellness.

Monomuls 90-L is safe for children and pets.
Monomuls 90-L is an anti-microbial agent that protects the immune system from a range of infectious agents.
Monomuls 90-L is a glyceride ester derivative of lauric acid, a fatty acid found naturally in breast milk and certain vegetable oils.

This fatty acid has been used as a germicidal agent for centuries.
Monomuls 90-L was originally discovered when microbiologists studied human breast milk to determine the antiviral substances which protected infants from microbial infections.
Monomuls 90-L has been shown to protect newborns, whose immune systems are underdeveloped, from Respiratory Syncytial Virus (RSV) and other respiratory tract viruses (1,2).

Monomuls 90-L was found to have even greater viral activity than lauric acid.
As a dietary supplement, Monomuls 90-L has shown exciting results as an anti-viral and anti-bacterial agent.
Monomuls 90-L, also known as glyceryl monolaurate, glyceryl laurate, or 1-Lauroyl-glycerol, is a monoglyceride (a single molecule of glycerol attached to a fatty acid).

Coconut oil is 48% Monomuls 90-L, which is valued for its use in the food and health supplement industries.
Monomuls 90-L converts to Monomuls 90-L in the body.
Some scientists believe Monomuls 90-L might be a promising antimicrobial.

Ongoing research is exploring its antibacterial and antiviral effects and safety.
Monomuls 90-L is an organic substance that is formed by the interaction of glycerol and lauric acid.
The largest amount of this substance is contained in coconut oil; it consists of almost half of Monomuls 90-L.

Monomuls 90-L is also found in breast milk (7%).
Monomuls 90-L has been suggested that Monomuls 90-L is what protects newborn babies from infectious diseases.
Monomuls 90-L is known for its antimicrobial and antiviral properties.

Monomuls 90-L has been studied for its potential to combat various bacteria, viruses, and fungi.
The mechanism of action is thought to involve disrupting the lipid membranes of microorganisms, thereby affecting their structure and function.
Monomuls 90-L, and consequently Monomuls 90-L, is naturally present in coconut oil, palm kernel oil, and human breast milk.

Coconut oil is often highlighted for its content of Monomuls 90-L, and some individuals use Monomuls 90-L supplements as a concentrated form of this compound.
While research is ongoing, some studies suggest that Monomuls 90-L may have potential health benefits, particularly in terms of its antimicrobial and antiviral effects.
Monomuls 90-L has been studied for its potential in addressing conditions like certain bacterial infections and viral illnesses.

Monomuls 90-L is available in supplement form, often marketed as a natural immune support supplement.
Monomuls 90-L comes in capsules, powders, or liquids.
Monomuls 90-L's important to note that the efficacy and safety of Monomuls 90-L supplements can vary, and individuals should consult with healthcare professionals before using them.

Besides coconut oil, lauric acid is found in lower amounts in various foods, including palm kernel oil, dairy products, and certain meats.
However, coconut oil is considered one of the richest food sources of Monomuls 90-L.
While there is some research supporting the antimicrobial properties of Monomuls 90-L, more studies are needed to establish its effectiveness in various health applications conclusively.

Monomuls 90-L is believed to exert its antimicrobial effects by disrupting the lipid bilayer of the microbial cell membrane.
This interference with the membrane structure can lead to the disintegration of the microbial cell, potentially inhibiting its ability to replicate and causing its demise.
Monomuls 90-L has been studied for its potential antiviral activity against a range of viruses, including certain types of influenza, herpes simplex viruses (HSV), and human immunodeficiency virus (HIV).

However, Monomuls 90-L's important to note that research is ongoing, and more evidence is needed to establish its efficacy in treating viral infections.
While coconut oil contains lauric acid, which the body can convert into Monomuls 90-L, the concentration of Monomuls 90-L in coconut oil is relatively low.
Some individuals choose to take Monomuls 90-L supplements to get a more concentrated form of this compound.

Monomuls 90-L has been explored for its potential as an additive in animal feed to promote animal health and prevent infections.
Monomuls 90-L is antimicrobial properties may contribute to controlling bacterial challenges in animal husbandry.
Some research suggests that Monomuls 90-L may possess anti-inflammatory properties.

This could have implications for conditions involving inflammation, although more research is needed to understand the extent of these effects.
While Monomuls 90-L has shown promise in various areas, including antimicrobial effects, it's important to approach its use with caution, especially in chronic or serious health conditions.
Professional medical advice is crucial before using Monomuls 90-L as a primary or complementary treatment.

Monomuls 90-L is the mono-ester formed from glycerol and lauric acid.
Monomuls 90-L is found in coconut oil and may be similar to other monoglycerides found in human breast milk.
Monomuls 90-L can be ingested in coconut oil and the human body converts it into Monomuls 90-L.

Furthermore, coconut oil, coconut cream, grated coconut and others products are sources of Monomuls 90-L and, consequently, Monomuls 90-L.
Monomuls 90-L and their esters (such as Monomuls 90-L) are well known for having antimicrobial activity.
The level of antimicrobial activity (of fatty acids and their esters) however, differs depending on variable factors such as fatty acid chain length, saturation and functional groups.

Among many other immune-supportive compounds, human breast milk contains both lauric acid and Monomuls 90-L.
Monomuls 90-L has long been known that breast feeding is highly beneficial to babies through antimicrobial and anti-inflammatory activities.
In a 2019 study published in Scientific Reports, researchers found human breast milk to contain high levels of Monomuls 90-L.

They also found human breast milk to be inhibitory to pathogen growth, to have anti-inflammatory activity and that both are in part dependent on Monomuls 90-L.
Monomuls 90-L is considered to be one of the more potent antimicrobial agents, among fatty acids and their esters, and is estimated to be around 200 times more effective than lauric acid.
Monomuls 90-L is believed to work as an antimicrobial mainly by disrupting lipid bi-layers.

Monomuls 90-L has demonstrated broad inhibitory activity against a number of common enveloped viruses, yet not against non-enveloped viruses.
Since viral envelopes are composed of lipid bi-layers this adds further weight to its likely mode of action as mainly being disruptive to the lipid bi-layer.
Unlike many conventional antiviral agents, Monomuls 90-L is not associated with induced resistance and is safe and well tolerated.

In addition, Monomuls 90-L has demonstrated anti-bacterial activity against many gram-positive bacteria, but not entirely with gram-negative bacteria.
Monomuls 90-L has been used to aid in the treatment of common cold, flu, shingles, herpes, candida, ringworm, and chronic fatigue syndrome.
Although Monomuls 90-L is exact mechanisms as an antiviral are unknown, it is said to work by binding to the lipid-protein envelope of the virus, thereby preventing it from attaching and entering host cells.

In other words, Monomuls 90-L prevents infection and replication by destroying the viral envelope.
Monomuls 90-L also appears to increase the effectiveness of other anti-bacterial agents in vitro4 and has demonstrated effectiveness against several bacterial biofilms.
Monomuls 90-L is a 1-monoglyceride with dodecanoyl (lauroyl) as the acyl group.

Melting point: 63 °C
Boiling point: 186 °C / 1mmHg
Density: 0.9764 (rough estimate)
refractive index: 1.4350 (estimate)
storage temp.: -20°C
solubility: Practically insoluble in water
form: powder to crystal
pka: 13.16±0.20(Predicted)
color: White to Almost white

Monomuls 90-Ls a specially extracted and purified humic acid with Monomuls 90-L, olive leaf extract, and Lactobacillus rhamnosus cell wall fragments.
The ability of Monomuls 90-L to disrupt biofilms could have implications for certain infections.
Some research has explored the potential of Monomuls 90-L in addressing respiratory infections, including those caused by certain bacteria and viruses.

However, more clinical studies are needed to validate these findings.
In some studies, Monomuls 90-L has been shown to work synergistically with certain antibiotics, enhancing their antimicrobial effects.
This suggests a potential role in combination therapies for bacterial infections.

Monomuls 90-L has been investigated for its impact on gastrointestinal health.
Research in animal models has suggested potential benefits in modulating gut microbial balance, but more studies are needed to determine its effects in humans.
Monomuls 90-L works by binding to the lipid-protein envelope of the virus, thereby preventing it from attaching and entering host cells, making infection and replication impossible.

Other studies show that Monomuls 90-L disintegrates the viral envelope, killing the virus.
Some studies suggest that Monomuls 90-L may have antifungal properties and could be effective against Candida species, which are types of yeast that can cause infections.
However, more research is needed to confirm its efficacy in treating fungal infections.

In addition to oral supplements, Monomuls 90-L is sometimes included in topical products such as creams or ointments.
These formulations may be used for conditions like skin infections or as a part of skincare routines, although research on the effectiveness of topical Monomuls 90-L is limited.
Monomuls 90-L is sometimes used in combination with other antimicrobial agents to create synergistic effects.

The idea is that combining different compounds with antimicrobial properties may enhance their overall effectiveness against a broader range of microorganisms.
Monomuls 90-L is naturally present in small amounts in human breast milk.
Monomuls 90-L is believed to contribute to the infant's immune defense, providing protection against various microbial threats.

Some Monomuls 90-L supplements come in liposomal formulations.
Monomuls 90-Ls are the organic components of soil, peats, brown coals, shales, and lake sediments, formed from decomposed plant material.
They are complex, long-chain molecules, varying in molecular weight from 5,000 to 50,000 daltons.

Due to its antimicrobial properties, Monomuls 90-L has been explored for its potential in acne treatment.
Some formulations may include Monomuls 90-L as part of products designed for individuals with acne-prone skin.
While there is ongoing research into the potential health benefits of Monomuls 90-L, there are still gaps in our understanding, and more rigorous clinical trials are needed to establish its
efficacy, safety, and appropriate uses conclusively.

Monomuls 90-L avoid sunlight, rain.
Store in unbroken packaging at the cool, dry and well-ventilated place.
The storage temperature should below 28 ℃ to minimise the agglomeration (the natural tendency).

Ecological Formulas’ Monomuls 90-L provides your body with a strong dose of lauric acid in the form of Monomuls 90-L‚ which your body is easily able to absorb.
This supplement is designed to help you get healthy and protect you from further infections.
Monomuls 90-L can be beneficial in the treatment of colds, flus and other respiratory infections.

Monomuls 90-L can help the body fight mild yeast infections.
Monomuls 90-L can help fight intestinal infections.

Monomuls 90-L can help reduce the recurrence of cold sores.
Monomuls 90-L source of healthy fats that support cardiovascular health.
Monomuls 90-L is a form of lauric acid that is easier for the body to absorb

Monomuls 90-L has antiviral, antifungal and antibacterial properties and can help support the immune system.
Monomuls 90-L can reduce the number of pro-inflammatory cytokines and promote infection fighting leukocytes.
Monomuls 90-L can help you get healthy and protect you from further infections.

Monomuls 90-L is a dietary supplement derived from coconut oil that has been linked to a variety of health benefits.
Monomuls 90-L has been shown to have antiviral, antibacterial, and antifungal properties, making it a great choice for boosting the immune system.
Monomuls 90-L has also been found to reduce inflammation, which can help with conditions such as arthritis and asthma.

Additionally, Monomuls 90-L has been shown to help reduce cholesterol levels, which can help improve heart health.
Finally, Monomuls 90-L has been linked to improved digestion, as it helps to break down fats and proteins in the digestive tract.
Monomuls 90-L is a dietary supplement derived from lauric acid, a fatty acid found in coconut oil.

Monomuls 90-L is believed to have antiviral, antibacterial, and antifungal properties.
While it is generally considered safe, there are some potential risks associated with taking Monomuls 90-L.
These include an increased risk of bleeding, an allergic reaction, and an increased risk of kidney stones.

Additionally, Monomuls 90-L may interact with certain medications, such as blood thinners, and may cause an upset stomach or diarrhea.
Monomuls 90-L is important to speak with a healthcare professional before taking any dietary supplement.
Monomuls 90-L is a dietary supplement that is regulated differently across the world.

Monomuls 90-L is regulated as a dietary supplement by the Food and Drug Administration (FDA).
In the European Union, Monomuls 90-L is regulated as a food supplement by the European Food Safety Authority (EFSA).
In Canada, Monomuls 90-L is regulated as a natural health product by Health Canada.

In Australia, Monomuls 90-L is regulated as a complementary medicine by the Therapeutic Goods Administration (TGA).
In India, Monomuls 90-L is regulated as a food supplement by the Food Safety and Standards Authority of India (FSSAI).
Monomuls 90-L is derived from lauric acid which is found naturally in coconut oil and human breast milk

Monomuls 90-L has been researched for its potential to inactivate certain viruses, bacteria, yeast, and other microbes in vitro (in the lab) and in vivo (in the body)
Monomuls 90-L can be taken as a dietary supplement in various forms and has been classified by the FDA as “Generally Recognized as Safe” (GRAS).
There are different considerations to when and how to take Monomuls 90-L, which include an introductory period to potentially avoid a “Herxheimer reaction” as well as an ongoing maintenance dose.

Monomuls 90-Ls are the most abundant source of non-living organic material found in nature.
Monomuls 90-L is made from lauric acid, a saturated fatty acid that comprises approximately 50% of the fatty acid content of coconut oil.
Monomuls 90-L makes up 6% of the fatty acid content found in human breast milk, and 3% of that found in cow’s milk and goat’s milk.

Monomuls 90-L is a simple natural compound with remarkable potential that can be taken in dietary supplement form.
With significant antimicrobial activity against a wide range of viral and bacterial pathogens, yet without negative effects, Monomuls 90-L is a valuable addition to your immune health toolkit at any time of the year.
Monomuls 90-L works by destroying lipid-coated viruses such as herpes, cytomegalovirus, influenza, and various pathogenic bacteria and protozoa.

Monomuls 90-L has demonstrated antibacterial activity against various types of bacteria.

Some studies suggest that Monomuls 90-L may be effective against bacteria such as Staphylococcus aureus and Streptococcus pneumoniae, among others.
Monomuls 90-L has been investigated for its potential to disrupt biofilms.
Biofilms are communities of microorganisms that adhere to surfaces and can be more resistant to antibiotics.

Uses:
Monomuls 90-L is used to inhibit the growth of bacteria, fungi, and viruses, and can be used to extend the shelf life of food products.
Monomuls 90-L in capsule form as a dietary supplement
Monomuls 90-L is sold as a dietary supplement and as an ingredient in certain foods.

The United States Food and Drug Administration categorizes it as generally recognized as safe.
Monomuls 90-L is a dietary supplement that is used to support immune health, digestive health, and skin health.
Monomuls 90-L is also used to help fight off viruses, bacteria, and other pathogens.

Monomuls 90-L is a dietary supplement that is used in the food industry as an antimicrobial agent.
Monomuls 90-L is also used as an emulsifier and stabilizer in food products, and can be used to improve the texture and flavor of food.
Monomuls 90-L has been studied for its potential to combat various microorganisms, including bacteria, viruses, and certain fungi.

Some studies suggest that Monomuls 90-L may be effective against certain viruses, including herpes simplex viruses (HSV), influenza viruses, and human immunodeficiency virus (HIV).
However, further research is needed to determine its clinical relevance in treating viral infections.
Monomuls 90-L has demonstrated antibacterial activity against a range of bacteria, including Staphylococcus aureus and Streptococcus pneumoniae.

Monomuls 90-L may be explored for potential use in addressing bacterial infections.
Research indicates that Monomuls 90-L may exhibit antifungal properties, making it a subject of interest in the context of fungal infections.
Some individuals use Monomuls 90-L supplements as a part of their wellness routine for immune support.

Monomuls 90-L is antimicrobial properties and potential to modulate the immune response make it an area of interest for those seeking natural immune-boosting supplements.
Monomuls 90-L has been investigated for its potential benefits in skincare.
Some formulations, such as creams or ointments, may include Monomuls 90-L for its antimicrobial properties and potential applications in addressing skin conditions.

Monomuls 90-L has been studied for its ability to disrupt biofilms.
Biofilms are protective layers formed by microorganisms, and disrupting them could have implications for preventing or treating certain infections.
Research in animals suggests that Monomuls 90-L may influence gut microbial balance, indicating potential benefits for gastrointestinal health.

However, more studies are needed to understand its effects in humans.
Some research has explored the potential of Monomuls 90-L in addressing respiratory infections, including those caused by bacteria and viruses.
Monomuls 90-L is known for its antimicrobial properties, which may include antibacterial, antiviral, and antifungal effects.

Monomuls 90-L is a coemulsifier for oil-in-water emulsions.
Monomuls 90-L is also a super fattening agent that promotes absorption and has a bacteriostatic effect.
Monomuls 90-L is used as an antimicrobial agent in various formulas and microemulsions and as a methane mitigation agent in ruminants.

Monomuls 90-L is often marketed as a dietary supplement for immune support.
Some people use it as a part of their wellness routine to potentially enhance immune function, but the evidence supporting its efficacy in this regard is limited.

Monomuls 90-L is generally regarded as safe for most people when used at recommended doses.
However, like any supplement, Monomuls 90-L may cause side effects in some individuals.
Monomuls 90-L's important to follow recommended dosage guidelines and consult with a healthcare professional.

While some studies have shown promising results regarding Monomuls 90-L's antimicrobial properties, it's essential to acknowledge that research in this area is still developing, and not all findings are conclusive.
Because the Monomuls 90-L exists in crude latex, having the ability of resist pathogenic microbe inflection, extensively be applied in the infant milk powder, rice flour etc.
Monomuls 90-L is used in baked product extensively, having the function for increase the quality of rice and flour production.

Monomuls 90-L is a kind of broad spectrum antibiotic, which is safe, efficient and extensive.
Monomuls 90-L can inhibit some kinds of virus and a lot of bacteria and bioplasm.
Monomuls 90-L is used as an emulsifier in sanitarian foods and other foods such as bread, cake, streamed bread and moon-cake.

Monomuls 90-L has been studied in combination with certain antibiotics, and there is evidence suggesting that it may work synergistically with these medications.
This could have implications for combination therapy in addressing bacterial infections.
Monomuls 90-L has been investigated for its potential use in animal health, particularly in preventing infections in livestock.

Monomuls 90-L may be added to animal feed as an additive to promote overall health and well-being.
Some studies suggest that Monomuls 90-L may possess anti-inflammatory properties.
This could be relevant for conditions involving inflammation, although more research is needed to understand the extent of these effects.

Some studies have investigated the potential of Monomuls 90-L in addressing tick-borne illnesses.
Monomuls 90-L has been explored for its antimicrobial effects against pathogens transmitted by ticks, although further research is needed to determine its effectiveness.
While Monomuls 90-L is primarily recognized for its antimicrobial effects, some research suggests that it may also have antioxidant properties.

Antioxidants play a role in neutralizing free radicals and may contribute to overall cellular health.
Limited research has explored the potential neuroprotective effects of Monomuls 90-L.
Some studies suggest that Monomuls 90-L may have a protective role in neurological conditions, although more research is needed in this area.

Preliminary studies have investigated the potential anticancer properties of Monomuls 90-L.
Monomuls 90-L has been studied for its effects on cancer cells in laboratory settings, but further research, including clinical trials, is required to understand its potential role in cancer prevention or treatment.
Monomuls 90-L is used in meat product, dairy product and fruit and vegetable for make the time of preservation longer.

Monomuls 90-L is most commonly used as a surfactant in cosmetics, such as deodorants.
As a food additive Monomuls 90-L is also used as an emulsifier or preservative.
Monomuls 90-L is also marketed as a dietary supplement.

Monomuls 90-L is used as a food additive, emulsifier, and as a preservative in ice cream, margarine, spaghetti, and other processed foods.
Monomuls 90-L and its derivatives, including Monomuls 90-L, have been explored for their antimicrobial properties in the context of food preservation.
They may be considered as natural alternatives to synthetic preservatives.

Some research has explored the potential use of Monomuls 90-L as an insect repellent.
Monomuls 90-L may have applications in formulations designed to deter certain insects, although more research is needed to establish its effectiveness.
While research is limited, some studies suggest that Monomuls 90-L may have potential benefits for cardiovascular health.

Monomuls 90-L may influence lipid metabolism, but more studies are needed to understand the mechanisms and clinical significance.
Monomuls 90-L has been investigated for its potential benefits in addressing skin conditions such as eczema and dermatitis.
Monomuls 90-L may be included in formulations designed to soothe and moisturize the skin, although more research is needed in this area.

Monomuls 90-L has been explored for potential applications in dental care.
Monomuls 90-L is use in oral hygiene products to address bacteria associated with oral health issues.
The antimicrobial properties of Monomuls 90-L may make it a candidate for inclusion in formulations designed to support wound healing and prevent infection in cuts and abrasions.

However, more research is needed in this specific application.
Some Monomuls 90-L supplements come in liposomal formulations, which are believed to enhance absorption.
These formulations may be explored for their potential benefits in delivering Monomuls 90-L more effectively to target tissues.

Monomuls 90-L is a component of medium-chain triglycerides (MCTs), and some individuals may choose to consume MCT oil as a source of lauric acid and, consequently, Monomuls 90-L.
Monomuls 90-L oil is known for its quick absorption and energy-providing properties.

Monomuls 90-L commonly used in deodorants, cosmetics, detergents, and insecticides and as an equipment sanitizer in manufacturing.
some people take Monomuls 90-L as a dietary supplement.

Safety Profile:
Monomuls 90-L's crucial to inform your healthcare provider about any supplements you are taking to avoid potential interactions.
Starting with a lower dose and gradually increasing may help minimize these effects.
Monomuls 90-L supplements may interact with certain medications.

Monomuls 90-L could potentially enhance the effects of anticoagulant medications.
There is limited information regarding the safety of Monomuls 90-L supplements during pregnancy and breastfeeding.
Monomuls 90-L's recommended to perform a patch test or start with a lower dose to monitor for any adverse reactions.

High doses of Monomuls 90-L, especially when starting supplementation, may cause gastrointestinal issues such as nausea, diarrhea, or stomach cramps in some individuals.
Pregnant or breastfeeding individuals should consult with their healthcare provider before using Monomuls 90-L supplements.
Choosing reputable brands and discussing supplement use with a healthcare professional is advisable.

Dietary supplements, including Monomuls 90-L supplements, are not regulated in the same way as pharmaceutical drugs.
The quality, purity, and potency of supplements can vary between brands.
Some individuals may be sensitive or allergic to specific components of supplements, including Monomuls 90-L.

Synonyms
Monomuls 90-L
2,3-Dihydroxypropyl dodecanoate
142-18-7
1-Monomuls 90-L
Glyceryl monolaurate
Lauricidin
GLYCERYL LAURATE
1-Glyceryl laurate
Glycerol 1-laurate
27215-38-9
1-Monolauroyl-rac-glycerol
1-Monododecanoylglycerol
Glycerol monolaurate
Laurin, 1-mono-
Glycerin 1-monolaurate
Glycerol 1-monolaurate
Lauric acid 1-monoglyceride
Dodecanoic acid, 2,3-dihydroxypropyl ester
2,3-Dihydroxypropyl laurate
Glyceryl monododecanoate
1-Lauroyl-rac-glycerol
DL-alpha-Laurin
Glycerides, C12-18
.alpha.-Monomuls 90-L
67701-26-2
3-Dodecanoyloxy-1,2-propanediol
(+-)-Glyceryl 1-monododecanoate
Dodecanoic acid alpha-monoglyceride
glyceryl 1-laurate
Glycerin monolaurate
(+-)-2,3-Dihydroxypropyl dodecanoate
Dodecanoic acid, monoester with 1,2,3-propanetriol
Glycerol .alpha.-monolaurate
WR963Y5QYW
40738-26-9
DTXSID5041275
CHEBI:75543
Lauric acid .alpha.-monoglyceride
1-Monomuls 90-L;1-Lauroyl-rac-glycerol
Lauric acid, monoester with glycerol
Dodecanoic acid .alpha.-monoglyceride
NSC698570
NSC-698570
NCGC00164528-01
alpha-Monomuls 90-L
1-monolauroylglycerol
DTXCID3021275
Glucerol alpha-monolaurate
Monolauroylglycerin
CAS-142-18-7
Lauric acid alpha-monoglyceride
C15H30O4
EINECS 205-526-6
UNII-WR963Y5QYW
Lauricidin R
Cithrol GML
rac-1-Monomuls 90-L
MG 12:0
Hodag GML
Glycerox L 8
Lauricidin 802
Lauricidin 812
1-dodecanoylglycerol
EINECS 266-944-2
Grindtek ML 90
Dimodan ML 90
Imwitor 312
Sunsoft 750
Sunsoft 757
Monomuls 90L12
rac-1-lauroylglycerol
Aldo MLD-K-FG
Glycerol 1-dodecanoate
Tegin L 90
rac-1-dodecanoylglycerol
AI3-03482
SDA 16-001-00
rac-1-monolauroylglycerol
Glycerol alpha-monolaurate
Poem M 300
EC 205-526-6
EC 266-944-2
Glycerol monolaurate (VAN)
Glycerol .alpha.-dodecanoate
SCHEMBL16042
MLS004773952
2,3-Dihydroxypropyl laurate #
CHEMBL510533
CHEBI:75539
GLYCEROL 1-MONODODECANOATE
1-Lauroyl-rac-glycerol, >=99%
UNII-Y98611C087
1,2,3-Propanetriol 1-dodecanoate
MAG 12:0
NSC 4837
rac-2,3-dihydroxypropyl dodecanoate
EINECS 248-337-4
Tox21_112159
Tox21_300759
MFCD00037815
(.+/-.)-Glyceryl 1-monododecanoate
AKOS016005827
Dodecanoic acid,3-dihydroxypropyl ester
NCGC00164528-02
NCGC00164528-03
NCGC00164528-04
NCGC00254663-01
5-TRIFLUOROMETHYL-2-PYRIMIDINAMINE
AS-60593
NCI60_035284
SMR001254002
(+/-)-GLYCERYL 1-MONODODECANOATE
(.+/-.)-2,3-Dihydroxypropyl dodecanoate
HY-121620
FT-0625428
FT-0626744
FT-0774814
G0081
M 300
Y98611C087
(+/-)-2,3-DIHYDROXYPROPYL DODECANOATE
H10813
L-1475
A885218
Q2113676
MONOPENTAERITRITOL
MONOPOTASSIUM PHOSPHATE; Phosphoric acid, monopotassium salt; Dipotassium dihydrogenphosphate; Potassium dihydrogenorthophosphate; Potassium dihydrogen phosphate; Potassium Phosphate Monobasic; Kaliumdihydrogenorthophosphat; Dihidrogenoortofosfato de potasio (Spanish); Dihydrogénoorthophosphate de potassium cas no: 7778-77-0
Monopentaerythritol
MONOETHANOLAMINE; Aminoethyl Alcohol; Beta-Aminoethanol; 2-Amino-ethanol; Ethanolamine; 1-Amino-2-hydroxyethane; 2-Amino-1-Ethanol; 2-Aminoaethanol German); 2-Aminoetanolo (Italian); 2-Aminoethanol; Aethanolamin (German); Beta-Aminoethyl Alcohol; Beta-ethanolamine; Beta-hydroxyethylamine; Colamine; Etanolamina (Italian); Ethylolamine; Glycinol; MEA; Monoaethanolamin (German); cas no: 141-43-5
MONOPHENYLGLYKOL
Monophenylglykol is an organic chemical compound, a glycol ether often used in dermatological products such as skin creams and sunscreen.
Monophenylglykol is a colorless oily liquid.
Monophenylglykol is a bactericide (usually used in conjunction with quaternary ammonium compounds).

CAS: 122-99-6
MF: C8H10O2
MW: 138.16
EINECS: 204-589-7

Monophenylglykol is used in many applications such as cosmetics, vaccines and pharmaceuticals as a preservative.
Monophenylglykol is an aromatic ether that is phenol substituted on oxygen by a 2-hydroxyethyl group.
Monophenylglykol has a role as an antiinfective agent and a central nervous system depressant.
Monophenylglykol is a primary alcohol, a glycol ether and an aromatic ether.
Monophenylglykol is functionally related to a phenol.
Monophenylglykol is an organic compound.
Monophenylglykol is an ether of phenol with ethylene glycol with the molecular formula C 8 H 10 O 2 .
Monophenylglykol is a preservative that is used in the food, pharmaceutical, and cosmetic industries.

Monophenylglykol is a glycol ether with a phenolic hydroxyl group that has been shown to have antimicrobial activity against antibiotic-resistant strains of bacteria.
Monophenylglykol has been found to be effective at concentrations between 0.1% and 1%, with an optimum concentration of 0.2%.
Monophenylglykol can be used as a disinfectant for wastewater treatment plants as well as in animal feedlots and animal housing facilities.
Monophenylglykol is also toxic to blood cells and can cause damage to cell nuclei when used at higher concentrations (>0.5%).
The levels of phenoxyethanol in the environment are typically low (0.01 parts per billion).

Monophenylglykol Chemical Properties
Melting point: 11-13 °C (lit.)
Boiling point: 247 °C (lit.)
Density: 1.102 g/mL at 25 °C (lit.)
Vapor density: 4.8 (vs air)
Capor pressure: 0.01 mm Hg ( 20 °C)
Refractive index: n20/D 1.539
FEMA: 4620 | 2-PHENOXYETHANOL
Fp: >230 °F
Storage temp.: Store below +30°C.
Solubility: soluble, clear, colorless to very faintly yellow
pka: 14.36±0.10(Predicted)
Form: Liquid
Color: Clear colorless
Specific Gravity: 1.109 (20/4℃)
Odor: Faint aromatic odor
PH Range: 7 at 10 g/l at 23 °C
PH:7 (10g/l, H2O, 23℃)
Explosive limit: 1.4-9.0%(V)
Odor Type: floral
Water Solubility: 30 g/L (20 ºC)
Merck: 14,7257
BRN: 1364011
InChIKey: QCDWFXQBSFUVSP-UHFFFAOYSA-N
LogP: 1.2 at 23℃
CAS DataBase Reference: 122-99-6(CAS DataBase Reference)
NIST Chemistry Reference: Monophenylglykol (122-99-6)
EPA Substance Registry System: Monophenylglykol (122-99-6)

Monophenylglykol is a colorless, slightly viscous liquid with a faint pleasant odor and burning taste.
Monophenylglykol is a tried-and-tested preservative, which is welltolerated by the skin and has a low allergy risk.
Monophenylglykol can be used over a wide pH range.
This means that other preservatives can lose their effectiveness if the product is not within the right pH range.
Monophenylglykol does not smell unpleasant or change the color of the product, which can be the case when using natural antimicrobial substances.
At room temperature, phenoxyethanol is a colorless, viscous liquid with a slightly aromatic, rose-like smell, which is slightly soluble in water.
The vapor pressure function results from Antoine corresponding to log 10 (P) = A−(B/(T+C)) (P in bar, T in K) with A = 5.13710, B = 2379.346 and C = −54.424 in the temperature range from 351 K to 518 K.

Uses
Monophenylglykol is a broad-range preservative with fungicidal, bactericidal, insecticidal, and germicidal properties.
Monophenylglykol has a relatively low sensitizing factor in leave-on cosmetics.
Monophenylglykol can be used in concentrations of 0.5 to 2.0 percent, and in combination with other preservatives such as sorbic acid or parabens.
In addition, Monophenylglykol is used as a solvent for aftershaves, face and hair lotions, shampoos, and skin creams of all types.
Monophenylglykol can be obtained from phenol.
Monophenylglykol at a 1.0% level acts as a preservative in personal care products.

Monophenylglykol is a preservative used in consumer and health care products, including vaccines, pen inks, ear drops, shampoos, skin cleansers, moisturizers, sun care products, and topical medicaments.
The preservative Monophenylglykol also contains 2-phenoxyethanol, in combination with methyldibromoglutaronitrile.
Monophenylglykol is commonly used in cosmetics for its antibacterial and antifungal properties.
Monophenylglykol is increasingly being used in vaccines as a substitute for thiomersal and is also a component of pen inks and, more rarely, ear drops.
Reactions to phenoxyethanol have rarely been reported.
Three cases of CoU induced by phenoxyethanol in cosmetics have been reported.
Monophenylglykol is used as a single agent and in combination with other preservatives such as Monophenylglykol and parabens, or in conjunction with quaternary ammonium compounds.
The possibility of immunological IgE-mediated reaction could not be confirmed because specific IgE against 2-phenoxyethanol was negative.
Antimicrobial preservative; also used topically in treatment of bacterial infections.

Monophenylglykol has germicidal and germistatic properties.
Monophenylglykol is often used together with quaternary ammonium compounds.
Monophenylglykol is used as a perfume fixative; an insect repellent; an antiseptic; a solvent for cellulose acetate, dyes, inks, and resins; a preservative for pharmaceuticals, cosmetics and lubricants; an anesthetic in fish aquaculture; and in organic synthesis.
Monophenylglykol is an alternative to formaldehyde-releasing preservatives.
In Japan and the European Union, its concentration in cosmetics is restricted to 1%.

Pharmaceutical Applications
Monophenylglykol is an antimicrobial preservative used in cosmetics and topical pharmaceutical formulations at a concentration of 0.5–1.0%; it may also be used as a preservative and antimicrobial agent for vaccines.
Therapeutically, a 2.2% solution or 2.0% cream has been used as a disinfectant for superficial wounds, burns, and minor infections of the skin and mucous membranes.
Monophenylglykol has a narrow spectrum of activity and is thus frequently used in combination with other preservatives,

Industrial uses
Monophenylglykol is used as a preservative in cosmetic formulations at a maximum concentration of 1.0%.
Monophenylglykol is a broad spectrum preservative which has excellent activity against a wide range of Gram negative and Gram positive bacteria, yeast and mould.
Monophenylglykol is also used as a solvent and, because of its properties as a solvent, it is used in many blends and mixtures with other preservatives.
Monophenylglykol is not registered as a food additive in the EU.
Scognamiglio et al. (ref. 105) reported that 2-phenoxyethanol is a fragrance ingredient used in many fragrance mixtures (see discussion).
An ester of Monophenylglykol, 2-Phenoxyethyl isobutyrate and 2-Phenoxyacetic acid, the main metabolite of 2-Phenoxyethanol, were mentioned in a WHO publication where 43 flavouring agents in food were evaluated (WHO 2003, AR4), however at intakes assessed to be very low in Europe (around 1 µg/kg bw/day).

Monophenylglykol has a bactericidal effect and is used in dermatological products such as: B. skin cream, used as a preservative, for which the German cosmetics regulation allows a concentration of up to 1%.
Monophenylglykol is used as a replacement for sodium azide in biological buffer solutions because it is less toxic and does not react with copper or lead.
Monophenylglykol is used as a narcoticfor fish, which means it can be used to calm, anesthetize or euthanize fish, depending on the dosage.
Monophenylglykol is also used as a preservative for vaccines in the pharmaceutical industry and is contained in most baby wipes and lubricants.
Monophenylglykol is also used as a solvent in inks, ballpoint pen pastes, printing pastes and stamping inks, as a fixative for perfumes and soaps and in the production of plasticizers and air fresheners.

Reactivity Profile
Monophenylglykol may react violently with strong oxidizing agents.
May generate flammable and/or toxic gases with alkali metals, nitrides, and other strong reducing agents.
May initiate the polymerization of isocyanates and epoxides.
May cause moderate eye irritation and moderate corneal injury.
Excessive exposure may cause skin irritation and hemolysis.

Contact allergens
Monophenylglykol is an aromatic ether-alcohol used mainly as a preservative, mostly with methyldibromoglutaronitrile (in Euxyl? K 400) or with parabens.
Sensitization to this molecule is very rare.

Production
Monophenylglykol is produced by the hydroxyethylation of phenol (Williamson synthesis), for example, in the presence of alkali-metal hydroxides or alkali-metal borohydrides.
Monophenylglykol has a long history of use, with its discovery credited to the German chemist Otto Schott in the early 20th century.
Since then, Monophenylglykol has been extensively studied and applied in various industries.

Synonyms
2-PHENOXYETHANOL
Phenoxyethanol
122-99-6
Ethylene glycol monophenyl ether
Phenyl cellosolve
Phenoxethol
Ethanol, 2-phenoxy-
Phenoxytol
Ethylene glycol phenyl ether
Phenoxetol
2-Phenoxyethan-1-Ol
Phenoxyethyl alcohol
1-Hydroxy-2-phenoxyethane
Rose ether
Phenylmonoglycol ether
Arosol
Dowanol EP
2-Phenoxyethyl alcohol
Glycol monophenyl ether
2-Hydroxyethyl phenyl ether
Phenylglycol
Fenyl-cellosolve
2-Fenoxyethanol
Dowanol EPH
2-Phenoxy-ethanol
Emery 6705
Emeressence 1160
Fenylcelosolv
beta-Hydroxyethyl phenyl ether
EGMPE
NSC 1864
Fenylcelosolv [Czech]
MFCD00002857
PHE-G
.beta.-Hydroxyethyl phenyl ether
2-Fenoxyethanol [Czech]
Fenyl-cellosolve [Czech]
Marlophen P
Plastiazan-41 [Russian]
NSC-1864
Plastiazan-41
Marlophen P 7
Spermicide 741
Tritonyl 45
Ethylan HB 4
Phenoxyethanol [NF]
.beta.-Phenoxyethanol
HSDB 5595
EINECS 204-589-7
9004-78-8
UNII-HIE492ZZ3T
.beta.-Phenoxyethyl alcohol
BRN 1364011
2-Phenoxyethyl--d4 Alcohol
HIE492ZZ3T
AI3-00752()C
CCRIS 9481
Ethylene glycol-monophenyl ether
DTXSID9021976
FEMA NO. 4620
CHEBI:64275
NSC1864
FR 214
Phenoxyethanol (NF)
NCGC00090731-01
NCGC00090731-05
(2-Hydroxyethoxy)benzene
EC 204-589-7
4-06-00-00571 (Beilstein Handbook Reference)
DTXCID401976
Erisept
beta-Phenoxyethanol
CAS-122-99-6
PHE-S
phenylcellosolve
Dalpad A
Phnoxy-2 thanol
Phenoxy -Ethanol
2-phenyloxyethanol
Newpol EFP
2- phenoxyethanol
2-phenoxy ethanol
?-Hydroxyphenetole
2 - phenoxyethanol
2-(phenoxy)ethanol
beta-Hydroxyphenetole
Etanol, 2-fenoxi-
2-phenoxy-1-ethanol
beta-phenoxyethylalcohol
starbld0047047
EPE (CHRIS Code)
2-Phenoxyethanol, 9CI
2-Phenoxyethanol, 99%
ETHANOL,2-PHENOXY
WLN: Q2OR
PHENOXYETHANOL [II]
SCHEMBL15708
2-Phenoxyethanol, >=99%
PHENOXYETHANOL [HSDB]
PHENOXYETHANOL [INCI]
MLS002174254
ethyleneglycol monophenyl ether
Euxyl K 400 (Salt/Mix)
2-PHENOXYETHANOL [MI]
PHENOXYETHANOL [MART.]
PHENOXYETHANOL [USP-RS]
PHENOXYETHANOL [WHO-DD]
2-PHENOXYETHANOL 500ML
CHEMBL1229846
AMY9420
PHENOXYEHTYL ALCOHOL/AROSOL
(C2-H4-O)mult-C6-H6-O
HMS2268A20
NSC1864NSC 1864
HY-B1729
STR04582
Tox21_111002
Tox21_113532
Tox21_202111
Tox21_300842
BBL027410
ETHER, 2-HYDROXYETHYL PHENYL
LS-672
PHENOXYETHANOL [EP MONOGRAPH]
STK802556
2-Phenoxyethanol, analytical standard
Fungal Terminator [veterinary] (TN)
AKOS000118741
Tox21_111002_1
CS-O-02175
DB11304
NCGC00090731-02
NCGC00090731-03
NCGC00090731-04
NCGC00090731-06
NCGC00090731-07
NCGC00090731-08
NCGC00254745-01
NCGC00259660-01
56257-90-0
Ethylene glycol monophenyl ether, >=90%
LS-72941
SMR000112131
ETHANOL,2-PHENOXY MFC8 H10 O2
Phenoxyethanol, 2-; (Phenyl cellosolve)
CS-0013737
FT-0613280
P0115
P1953
EN300-19339
2-Phenoxyethanol, tested according to Ph.Eur.
D08359
500-013-6 (NLP #)
A805003
Q418038
SR-01000838345
J-510235
SR-01000838345-2
F1905-6997
Z104473570
Ethylene glycol monophenyl ether, SAJ first grade, >=95.0%
Phenoxyethanol, European Pharmacopoeia (EP) Reference Standard
Phenoxyethanol, United States Pharmacopeia (USP) Reference Standard
InChI=1/C8H10O2/c9-6-7-10-8-4-2-1-3-5-8/h1-5,9H,6-7H
2-Phenoxyethanol, Pharmaceutical Secondary Standard; Certified Reference Material
MONOPOTASSIUM PHOSPHATE
DESCRIPTION:

Monopotassium phosphate (MKP) (also, potassium dihydrogenphosphate, KDP, or monobasic potassium phosphate) is the inorganic compound with the formula KH2PO4.
Together with dipotassium phosphate (K2HPO4.(H2O)x) it is often used as a fertilizer, food additive, and buffering agent.
The salt often cocrystallizes with the dipotassium salt as well as with phosphoric acid.


CAS Number, 7778-77-0
EC Number, 231-913-4


Monopotassium phosphate is a potassium salt in which dihydrogen phosphate (1-) is the counterion.
Monopotassium phosphate has a role as a fertilizer.
Monopotassium phosphate is a potassium salt and an inorganic phosphate.

Monopotassium phosphate, MKP, (also potassium dihydrogenphosphate, KDP, or monobasic potassium phosphate), KH2PO4, is a soluble salt of potassium and the dihydrogen phosphate ion.
Monopotassium phosphate is a source of phosphorus and potassium as well as a buffering agent.
Monopotassium phosphate can be used in fertilizer mixtures to reduce escape of ammonia by keeping pH low.


Single crystals are paraelectric at room temperature.
At temperatures below −150 °C (−238 °F), they become ferroelectric.


STRUCTURE OF MONOPOTASSIUM PHOSPHATE:
Monopotassium phosphate can exist in several polymorphs.
At room temperature it forms paraelectric crystals with tetragonal symmetry.
Upon cooling to −150 °C (−238 °F) it transforms to a ferroelectric phase of orthorhombic symmetry, and the transition temperature shifts up to −50 °C (−58 °F) when hydrogen is replaced by deuterium.

Heating to 190 °C (374 °F) changes its structure to monoclinic.
When heated further, MKP decomposes, by loss of water, to potassium metaphosphate, KPO
3, at 400 °C (752 °F).



MANUFACTURING OF MONOPOTASSIUM PHOSPHATE:
Monopotassium phosphate is produced by the action of phosphoric acid on potassium carbonate.


APPLICATIONS OF MONOPOTASSIUM PHOSPHATE:
Fertilizer-grade Monopotassium phosphate powder contains the equivalent of 52% P2O5 and 34% K2O, and is labeled NPK 0-52-34.
Monopotassium phosphate powder is often used as a nutrient source in the greenhouse trade and in hydroponics.

As a crystal, Monopotassium phosphate is noted for its non-linear optical properties.
Monopotassium phosphate is used in optical modulators and for non-linear optics such as second-harmonic generation (SHG).
Also, to be noted is KD*P, potassium dideuterium phosphate, with slightly different properties.
Highly deuterated KDP is used in nonlinear frequency conversion of laser light instead of protonated (regular) KDP due to the fact that the replacement of protons with deuterons in the crystal shifts the third overtone of the strong OH molecular stretch to longer wavelengths, moving it mostly out of the range of the fundamental line at approximately 1064 nm of neodymium-based lasers.

Regular KDP has absorbances at this wavelength of approximately 4.7–6.3% per cm of thickness while highly deuterated KDP has absorbances of typically less than 0.8% per cm.
Monopotassium phosphate is also used as an ingredient in sports drinks such as Gatorade and Powerade.
In medicine, monopotassium phosphate is used for phosphate substitution in hypophosphatemia


Monopotassium phosphate is used in fertilizers, pH regulators and water treatment products, washing and cleaning products, air care products, textile treatment products, dyes and laboratory chemicals.
Monopotassium phosphate is used in: agriculture, forestry and fisheries and scientific research and development.

Monopotassium phosphate is Used in the manufacture of textiles, leather or fur, chemicals and mineral products (eg plasters, cement).
Monopotassium phosphate is Used in machine washing liquids/detergents, automotive care products, paints and coatings or adhesives, fragrances, air fresheners, coolants in refrigerators, oil-based electric heaters.


MAIN USES OF MONOPOTASSIUM PHOSPHATE:
Monopotassium phosphate is a high-purity PK fertilizer (0-52-34).
Due to its very low sodium content, Monopotassium phosphate is recommended for use in any type of crop and in any fertigation system (drip irrigation, hydroponics, sprinkles, pivots) or as a foliar spray.
Monopotassium phosphate is 100% soluble in water and is quickly absorbed by plants, which allows to use it for root application through irrigation systems.

Monopotassium phosphate is especially recommended to use in hydroponics, as it virtually does not contain chlorine or insolubles.
Monopotassium phosphate can be mixed with all water-soluble fertilizers, except for calcium fertilizers and concentrated magnesium solutions.
In hydroponic systems, Monopotassium phosphate should normally be added to the B tank along with the sulfates and trace elements.
Monopotassium phosphate has a buffering effect, which will help stabilize the pH of the solution at around 4.5.





CHEMICAL AND PHYSICAL PROPERTIES OF MONOPOTASSIUM PHOSPHATE
Chemical formula, KH2PO4
Molar mass, 136.086 g/mol
Appearance, Colourless crystals or white granular or crystalline powder
Odor, Odorless
Density, 2.338 g/cm3
Melting point, 252.6 °C (486.7 °F; 525.8 K)
Boiling point, 400 °C (752 °F; 673 K) , decomposes
Solubility in water, 22.6 g/100 mL (20 °C)
83.5 g/100 mL (90 °C)
Solubility, Slightly soluble in ethanol
Acidity (pKa), 6.86
Basicity (pKb), 11.9
Refractive index (nD), 1.4864
Structure,
Crystal structure, Tetragonal
Space group, I42d
Lattice constant, a = 0.744 nm, b = 0.744 nm, c = 0.697 nm
Molecular Weight
136.086 g/mol
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
0
Exact Mass
135.93277702 g/mol
Monoisotopic Mass
135.93277702 g/mol
Topological Polar Surface Area
80.6Ų
Heavy Atom Count
6
Formal Charge
0
Complexity
61.9
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Yes
Density, 2.33 g/cm3 (21.5 °C)
Melting Point, 252.6 °C (decomposition)
pH value, 4.2 - 4.6 (20 g/l, H₂O, 20 °C)
Vapor pressure, Bulk density, 1200 kg/m3
Solubility, 208 g/l
CAS number, 7778-77-0
EC number, 231-913-4
Grade, ISO
Hill Formula, H₂KO₄P
Chemical formula, KH₂PO₄
Molar Mass, 136.09 g/mol
HS Code, 2835 24 00
Molecular weight:, 136.09
GHS-Pictograms:, 00
Synonyms:, Potassium biphosphate; Monopotassium phosphate;
E340; KDP; MKP
Sum formula:, KH2PO4
Assay:, Min. 99 %
CAS-Number:, 7778-77-0
Loss on drying:, max. 0.1 %
EG-Number:, 231-913-4
Pubchem-Number:, 516951
Solubility in water:, 220 g/l (20 °C)
Storage Temperature:, 15 - 25 °C




SAFETY INFORMATION ABOUT MONOPOTASSIUM PHOSPHATE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product





SYNONYMS OF MONOPOTASSIUM PHOSPHATE:
dipotassium hydrogen phosphate
K2HPO4
KD2PO4
potassium acid phosphate
potassium dideuterium phosphate
potassium dihydrogen phosphate
potassium monohydrogen phosphate
potassium phosphate
potassium phosphate (K-H2PO4)
potassium phosphate (K-H3PO4(1:2))
potassium phosphate (K2-HPO4)
potassium phosphate (K3-PO4)
potassium phosphate, dibasic
potassium phosphate, monobasic
potassium phosphate, unspecified form
Potassium dihydrogen phosphate
7778-77-0
Potassium phosphate monobasic
MONOPOTASSIUM PHOSPHATE
Monobasic potassium phosphate
Monopotassiumphosphate
Potassium acid phosphate
Potassium phosphate, monobasic
Phosphoric acid, monopotassium salt
Potassium dihydrogen orthophosphate
Monopotassium monophosphate
Monopotassium orthophosphate
Monopotassium dihydrogen phosphate
potassium biphosphate
potassium dihydrogenphosphate
potassium;dihydrogen phosphate
Sorensen's potassium phosphate
Potassium dihydrogenorthophosphate
Potassium phosphate (K(H2PO4))
KH2PO4
Orthophosphoric acid, monopotassium salt
CHEBI:63036
MFCD00011401
4J9FJ0HL51
MKP
Monopotassium dihydrogen monophosphate
Monopotassium dihydrogen orthophosphate
Phosphoric acid, potassium salt (1:1)
Potassium phosphate monobasic (anhydrous)
Potassium dihydrogen orthophosphate(V)
HSDB 5046
Potassium orthophosphate, dihydrogen
EINECS 231-913-4
EPA Pesticide Chemical Code 076413
Potassium hydrogen phosphate (KH2PO4)
UNII-4J9FJ0HL51
Potassium phosphate, monobasic [NF]
mono potassium phosphate
mono-potassium phosphate
EC 231-913-4
Potassium phosphate,monobasic
potassium di-hydrogen phosphate
CHEMBL1200925
DTXSID0035667
INS NO.340(I)
UNII-B7862WZ632
GNSKLFRGEWLPPA-UHFFFAOYSA-M
INS-340(I)
POTASSIUM PHOSPHATE [INCI]
Potassium Dihydrogen Phosphate,(S)
EINECS 240-213-8
BDBM50004328
MFCD00147253
AKOS015902364
AKOS028109678
B7862WZ632
DB09413
Phosphoric acid, potassium salt (1:?)
Potassium phosphate, monobasic (JAN/NF)
E-340(I)
Potassium phosphate monobasic, HPLC grade
Potassium dihydrogen phosphate, Puratronic?
POTASSIUM PHOSPHATE, MONOBASIC [II]
POTASSIUM PHOSPHATE, MONOBASIC [MI]
FT-0645117
MONOBASIC POTASSIUM PHOSPHATE [MART.]
POTASSIUM PHOSPHATE, MONOBASIC [FCC]
POTASSIUM PHOSPHATE, MONOBASIC [HSDB]
POTASSIUM PHOSPHATE, MONOBASIC [JAN]
POTASSIUM PHOSPHATE,MONOBASIC [VANDF]
MONOBASIC POTASSIUM PHOSPHATE [USP-RS]
POTASSIUM PHOSPHATE MONOBASIC [WHO-DD]
D02050
Potassium phosphate monobasic, Trace metals grade
Q415049
POTASSIUM DIHYDROGEN PHOSPHATE [EP MONOGRAPH]
POTASSIUM PHOSPHATE, MONOBASIC [ORANGE BOOK]
TIS-U-SOL COMPONENT POTASSIUM PHOSPHATE, MONOBASIC
Potassium phosphate monobasic powder suitable for cell culture
POTASSIUM PHOSPHATE, MONOBASIC COMPONENT OF TIS-U-SOL
POTASSIUM PHOSPHATES COMPONENT MONOBASIC POTASSIUM PHOSPHATE
MONOBASIC POTASSIUM PHOSPHATE COMPONENT OF POTASSIUM PHOSPHATES




MONOPOTASSIUM PHOSPHATE
MONOPOTASSIUM PHOSPHATE = MKP = POTASSIUM DIHYDROGEN PHOSPHATE


CAS Number: 7778-77-0
EC Number: 231-913-4
MDL Number: MFCD00011401
Chemical formula: KH2PO4


Monopotassium Phosphate is nothing but the monopotassium salt of phosphoric acid bearing the formula KH2PO4.
Monopotassium Phosphate is easily soluble in water and insoluble in ethanol.
Monopotassium phosphate is commercially available.
Monopotassium Phosphate produces ceramics of high quality at the time of its reaction with MgO.
The reaction between the chloride or potassium carbonate and the phosphate generally produce the above-mentioned compound.


In the reaction, phosphate is released in pure form as a crystalline material.
The industrial preparation of Monopotassium Phosphate involves adding of 1 mol of a water solution of potassium hydroxide to 1 mol of phosphoric acid.
Monopotassium Phosphate is one of the most important inorganic compounds.
The main utilization of this compound is as fertilizer, food additive and buffering agent.


Sometimes the salt co-crystalizes with the dipotassium salt as well with the phosphoric acid.
IUPAC names of Monopotassium Phosphate are Potassium dihydrogen phosphate and Potassium dihydrogen (tetraoxidophosphate) (1- ).
The systematic IUPAC name of Monopotassium Phosphate is Potassium dihyroxidophosphate (1-).
Other names of the compound are Potassium phosphate monobasic, Phosphoric acid, monopotassium salt and Potassium biphosphate.


Monopotassium phosphate is the fertilizer, which contains highest amount of major elements, among other soluble fertilizers.
Monopotassium phosphate's formula is KH2PO4.
As Monopotassium phosphate contains no nitrogen, Monopotassium phosphate is appropriate for plants that require intensive use of fertilizers.
Monopotassium phosphate fertilize can be the most suitable source of potassium and phosphorus when nitrogen use is contradictory.


In other times Monopotassium phosphate is also the preferred type of fertilizer as it can be given together with any kind of nitrogen fertilizers (ammonium, nitrate or urea nitrogen containing fertilizers).
Monopotassium phosphate is an ionic compound used for electrolyte replenishment and total parenteral nutrition (TPN) therapy.
Monopotassium phosphate, MKP, (also potassium dihydrogenphosphate, KDP, or monobasic potassium phosphate), KH2PO4, is a soluble salt of potassium and the dihydrogen phosphate ion.


Monopotassium phosphate is a source of phosphorus and potassium as well as a buffering agent.
Monopotassium phosphate are colorless, soluble in water and hygroscopic in nature.
Upon heating through 187°C, phase transition occurs in KH2PO4, crystal system changes from tetragonal to monoclinic, lattice parameters at 195°C are α=7.47Å, b =7.33Å, c =14.49Å, α=ß=90° and γ=92.2.


Monopotassium phosphate is A highly pure phosphate and potassium fertilizer, which dissolves rapidly and contributes to root development in early stages up until flowering and early fruit set.
Potassium helps the plant to become stress resistant strengthens the plant to support its fruits.
Monopotassium Phosphate is odourless.
The physical appearance of Monopotassium phosphate is a white powder which is deliquescent.


The covalently bonded unit of Monopotassium phosphate is 2.
Heavy atom count of Monopotassium Phosphate is 6.
Complexity of Monopotassium phosphate is 61.2.
Monopotassium Phosphate is freely soluble in water.
After dissolving in the water Monopotassium Phosphate forms phosphoric acid and potassium hydroxide.


The chemical equation of the above phenomenon is as follows:
KH2PO4 + H2O 🡪 H3PO4 + KOH
Disodium phosphate, water and potassium hydroxide are formed by the reaction between Monopotassium Phosphate and base.
The chemical formula of the above reaction is as follows:
KH2PO4 + 2NaOH 🡪 H2O + KOH + Na2HPO4


The reaction of phosphoric acid on potassium carbonate produces Monopotassium Phosphate.
Approximately 52% of P2O5 and 34% of K2O are contained in fertilizer grade Monopotassium Phosphate powder.
The fertilizer grade Monopotassium Phosphate is symbolised as NPL 0-52-34.
There is a remarkable application of Monopotassium Phosphate in the greenhouse trade and in hydroponics as a nutrient.
A modified form of Monopotassium Phosphate is termed as potassium di-deuterium phosphate (KD2PO4).


Non-linear frequency conversion of laser light is done by highly deuterated KDP in place of protonated (regular) KDP because the replacement of protons with deuterons in the crystal shifts the third overtone of the strong OH molecular stretch to longer wavelengths, moving it maximum out of the range of the basic line at apparently 1064 mm of neodymium- based lasers.
Regular KDP has the absorbance power at this particular wavelength of near about 4.7- 6.3% per cm of thickness at the time when highly deuterated KDP has an absorbance of typically less than 0.8% per cm.


CAS number of Monopotassium Phosphate is 7778-77-0.
3D model of the compound appears as an interactive image.
ChEMBL of Monopotassium Phosphate is ChEMBL 1200925.
ECHA InfoCard is 100.029.012.


EC Number of Monopotassium Phosphate is 231-913-4.
E Number of the compound is E340 (I).
RTECS Number of Monopotassium Phosphate is TC6615500.
Monopotassium phosphate (MKP) (also, potassium dihydrogenphosphate, KDP, or monobasic potassium phosphate) is the inorganic compound with the formula KH2PO4.


Together with dipotassium phosphate (K2HPO4.(H2O)x) Monopotassium phosphate is often used as a fertilizer, food additive, and buffering agent.
The salt often cocrystallizes with the dipotassium salt as well as with phosphoric acid.
Single crystals are paraelectric at room temperature.
At temperatures below −150 °C (−238 °F), they become ferroelectric.
Monopotassium phosphate is produced by the action of phosphoric acid on potassium carbonate.


Monopotassium phosphate is a potassium salt in which dihydrogen phosphate(1-) is the counterion.
Monopotassium phosphate has a role as a fertilizer.
Monopotassium phosphate is a potassium salt and an inorganic phosphate.
Monopotassium phosphate, MKP, (also potassium dihydrogenphosphate, KDP, or monobasic potassium phosphate), KH2PO4, is a soluble salt of potassium and the dihydrogen phosphate ion.


Monopotassium phosphate is a source of phosphorus and potassium as well as a buffering agent.
Monopotassium phosphate has a limited caking sensitivity and is recommended during root and shoot development in early stages, up until flowering and early fruit set.
The presence of Potassium plays an important role in protecting the plant from early stress, as well as providing a good support for the fruits in early fruit set.


As a nitrogen-free fertilizer, Monopotassium phosphate is the preferred source of phosphorus and potassium when nitrogen fertilization should be limited.
For example, early in the growing season, when phosphorus and potassium are needed at high rates for the establishment of root system.
Results from the interaction of phosphoric acid with potassium carbonate in an appropriate ratio.
Monopotassium phosphate is colorless columnar crystal or white crystalline powder.
Monopotassium phosphate's melting point 96 C; d 2.34.


Monopotassium phosphate is stable in air.
Monopotassium phosphate is soluble in about 4.5 water, the aqueous solution is acidic, pH 4. 4~4.7.
Monopotassium phosphate is insoluble in ethanol.
At 400 deg C water loss to form potassium metaphosphate.
Monopotassium Phosphate shall be calculated as dry product, and the content of KH2PO4 shall not be less than 99.0%.


The relative density of Monopotassium phosphate was 2.338.
Monopotassium phosphate is soluble in water (90 deg C for 83.5g/4.6 ml water), aqueous solution is acidic, 1% potassium dihydrogen phosphate solution pH value.
Monopotassium phosphate is insoluble in alcohol.
The transparent liquid melted when heated to 400 °c and solidified to opaque glassy potassium metaphosphate after cooling.


A transparent liquid is formed after melting, and potassium metaphosphate is an opaque glassy substance after cooling and solidification.
Monopotassium Phosphate is colorless crystalline or white crystalline powder or granules or lumps; Odorless.
Monopotassium Phosphate is soluble in water and almost insoluble in ethanol.
Stable in the air.


Monopotassium Phosphate is hygroscopic, easily soluble in water, insoluble in alcohol, slightly alkaline in aqueous solution, dehydration of molecular content when 204, and PH value of 1% aqueous solution is 8.9. Solubility in water: 222g/L (20°C)
Monopotassium Phosphate of the aqueous solution of potassium salt and phosphate identification reaction (General 0301).
Monopotassium phosphate is a white granular product of Monopotassium Phosphate that complies with the specification of the current Food Chemicals Codex for Potassium Phosphate, Monobasic.


Monopotassium phosphate is a free flowing, fine crystalline powder which dissolves quickly in water without any residues.
Monopotassium phosphate is the monopotassium salt of phosphoric acid with the formula KH2PO4.
Monopotassium phosphate is freely soluble in water and insoluble in ethanol.
Commercially available as pure KH2PO4, when reacted with MgO, produces high-quality ceramics.


Monopotassium phosphate is formed by the chloride or potassium carbonate reaction with phosphoric acid, and the phosphate is derived in a pure form as a crystalline material.
Monopotassium Phosphate dissolves in water forms phosphoric acid and potassium hydroxide.
The chemical equation is given below.
KH2PO4 + H2O → H3PO4 + KOH


Monopotassium Phosphate reacts with a base like sodium hydroxide forms disodium phosphate, water and potassium hydroxide.
KH2PO4 + 2NaOH → H2O + KOH + Na2HPO4
Mono potassium phosphate is formed when caustic potash lye or caustic potash flakes are added to the solution of phosphoric acid until the desired PH is obtained and further dried to obtain fine quality white powder.


Monopotassium Phosphate provides Phosphorous (P) and Potassium (K) to aquarium plants, essential macronutrients for healthy plant growth and survival.
Monopotassium phosphate (KH2PO4), provides essential K and P aquarium macronutrients, vital to plant growth and ATP energy transfer.
Available to plants in aquarium as phosphates compound (PO4), functions as plant food, and commonly sourced from organic waste from fish and plant decay.


For plants to thrive and be free of algae, phosphates must be in optimal concentration.
For example, tanks with higher lighting and less fish load will need to supplement PO4.
Phosphates may be present in both organic and inorganic forms, both readily used and critical in plants.
All energy transfers depend on phosphates, and the lack of sufficient PO4 will result in stunted growth and discoloration.
aids in cell membrane function, plants food, phospholipids, nucleic acids DNA and RNA, enzymes, Adenosine Triphosphate (ATP) energy transfer


Monopotassium phosphate is a potassium salt in which dihydrogen phosphate(1-) is the counterion.
Monopotassium phosphate has a role as a fertilizer.
Monopotassium phosphate is a potassium salt and an inorganic phosphate.|Monopotassium phosphate, MKP, (also potassium dihydrogenphosphate, KDP, or monobasic potassium phosphate), KH2PO4, is a soluble salt of potassium and the dihydrogen phosphate ion.


Monopotassium phosphate is a source of phosphorus and potassium as well as a buffering agent.
Monopotassium phosphate (also potassium dihydrogen phosphate, KDP, or monobasic potassium phosphate, MKP) -- KH2PO4 -- is a soluble salt which is used as a fertilizer, a food additive and a fungicide.
Monopotassium phosphate is a source of phosphorus and potassium, and is a buffering agent.
When used in fertilizer mixtures with urea and ammonium phosphates, Monopotassium phosphate minimizes escape of ammonia by keeping the pH at a relatively low level.


Monopotassium phosphate has a low salt index which makes Monopotassium phosphate the ideal phosphorus and potassium-containing fertilizer for fertigation.
The purity of Monopotassium phosphate allows both elements to be easily taken up.
Monopotassium phosphate is an excellent source of phosphorus and potassium.
Monopotassium phosphate is a clean, fully water soluble phosphorus and potassium fertilizer.


Monopotassium phosphate is Fine crystalline powder which dissolves quickly in water.
Monopotassium phosphate (MKP) (also, potassium dihydrogenphosphate, KDP, or monobasic potassium phosphate) is the inorganic compound with the formula KH2PO4.
Monopotassium phosphate has role fertilizer.
Monopotassium phosphate is a inorganic phosphate.


Monopotassium phosphate is a potassium salt.
With Monopotassium phosphate's low salt index, Monopotassium phosphate is recommended for use in any type of crop and fertigation system: drip irrigation, hydroponics, sprinkles, pivots, or foliar spray.
Monopotassium phosphate (MKP) with formula KH2PO4, is manufactured from phosphoric acid and potassium carbonate.
Monopotassium phosphate is a water soluble, hygroscopic, white, odourless powder.


Monopotassium phosphate fertilizer is a two-component phosphorus-potassium fertilizer.
Monopotassium phosphate is fully water-soluble, high-quality crystalline.
Intended for fertigation and foliar fertilization of agricultural, orchard and horticultural crops.
Monopotassium phosphate is an excellent source of potassium and phosphorus.


Monopotassium phosphate, fertilizer is high-grade, two-component crystalline fertilizer, completely soluble in water.
Monopotassium phosphate is an excellent source of phosphorus and potassium in the case of limited nitrogen demand.
Monopotassium phosphate (KH2PO4) is white crystals, containing 51.5% phosphorus (P2O5) and 34% potassium (K2O).
Monopotassium phosphate is one of the crucial fertilizers that plants need at early growing stages to establish their root system.


Monopotassium phosphate's high purity and solubility in water make Monopotassium phosphate a highly efficient source of phosphorous and potassium for plants.
MonoPotassium Phosphate (KH2PO4), also known as MKP: Contains 35% K2O and 52% P2O5.
MKP fertilizer is a full name Monopotassium phosphate.


Stool containing 2 main nutrients is phosphorus (52%) and potassium (34%) in completely soluble form, so Monopotassium phosphate is often used as foliar fertilizer or mixed into drip irrigation system.
Monopotassium phosphate does not contain protein, so Monopotassium phosphate is easy to adjust the amount of nitrogen fertilizer according to crop needs.
Monopotassium phosphate is often used in periods of high demand for phosphorus and potassium.


When sprayed in the period of seedlings with 4-6 leaves, Monopotassium phosphate helps root system to develop early, plants absorb nutrients easily and thus increase drought resistance.
Due to the absence of protein, Monopotassium phosphate is often used in the rainy season to replace potassium nitrate (KNO3) in order to provide potassium to increase crop yield and to limit some diseases such as blast, sheath, and blight. letter
Monopotassium Phosphate (MKP) is a fully water-soluble mono-potassium phosphate fertilizer, a highly efficient source of phosphorus and potassium for plants.


As a nitrogen-free fertilizer, Monopotassium Phosphate (MKP) is the preferred source of phosphorus and potassium, when nitrogen fertilization should be limited.
A common case is at early growing season, when phosphorus and potassium are needed at high rates for the establishment of root system.
Application of Monopotassium phosphate, at the productive stages of sugar-rich fruit crops helps to increase sugar content and to improve the quality of these.


Monopotassium phosphate, MKP, KH₂PO₄, is a soluble salt of potassium and the dihydrogen phosphate ion which is used as a fertilizer, a food additive and a fungicide.
Monopotassium phosphate is a source of phosphorus and potassium.
Monopotassium phosphate is also a buffering agent.
Monopotassium phosphate (MKP) is a potential option for fertigating phosphorus (P) in potato (Solanum tuberosum L.) when petioles are low in P and high in nitrogen (N); which is a situation where using ammonium polyphosphate (APP) could potentially result in excessive N application.


Monopotassium phosphate (MKP) or potassium dihydrogen phosphate (KDP) is a soluble phosphoric acid salt of potassium with the chemical formula KH2PO4.
Monopotassium phosphate water-soluble fertilizer is a preferred source of phosphorus and potassium when nitrogen fertilization should be limited.
Monopotassium phosphate is a water-soluble monopotassium phosphate fertilizer and an effective phosphorus source.


Monopotassium phosphate dissolves easily and fully and stays in a solution ready for root adsorption or is absorbed through leaf surfaces.
Monopotassium Phosphate, also known as MKP and Potassium Dihydrogen Orthophosphate, is an odourless white crystalline powder.
Monopotassium phosphate is a soluble salt of potassium and the dihydrogen phosphate ion.
Monopotassium phosphate quickly dissolves to provide the much needed phosphorous and potassium to plants at all growth stages, in hydroponics as well as soil grown crops.


Monopotassium phosphate is free of chlorine, sodium and heavy metals.
Monopotassium phosphate is suitable for all fertigation systems through drip irrigation, NFT, sprinklers, centre pivots and lateral movement irrigation systems.
Monopotassium Phosphate is a chemical compound that finds immense application in the fertilizer industry in the manufacturing of potash and other fertilizer products.


Monopotassium phosphate is formed when caustic potash lye or caustic potash flakes are added to the solution of phosphoric acid until the desired PH is obtained and further dried to obtain fine quality white powder.
Monopotassium phosphate is a rich source of phosphorous and potassium.
Monopotassium phosphate (MKP) is the inorganic, free flowing, crystalline powder.


Monopotassium phosphate is often used as a fertilizer, food additive, and buffering agent.
The salt often co-crystallizes with the dipotassium salt as well as with phosphoric acid.
Single crystals are paraelectric at room temperature.
At temperatures below −238 °F, they become ferroelectric.


Monopotassium phosphate is one of the most widely used straight fertilizers in tailor-made crop recommendations.
Monopotassium phosphate's high phosphorus and potassium content makes Monopotassium phosphate very flexible to be used in hydroponics, easily meeting the plant’s needs for these nutrients.
Monopotassium phosphate is a high-purity PK fertilizer (0-52-34).


Due to Monopotassium phosphate's very low sodium content, Monopotassium phosphate is recommended for use in any type of crop and in any fertigation system (drip irrigation, hydroponics, sprinkles, pivots) or as a foliar spray.
Monopotassium phosphate is 100% soluble in water and is quickly absorbed by plants, which allows to use it for root application through irrigation systems.


Monopotassium phosphate is especially recommended to use in hydroponics, as it virtually does not contain chlorine or insolubles.
Monopotassium phosphate can be mixed with all water-soluble fertilizers, except for calcium fertilizers and concentrated magnesium solutions.
In hydroponic systems, Monopotassium phosphate should normally be added to the B tank along with the sulfates and trace elements.
Monopotassium phosphate has a buffering effect, which will help stabilize the pH of the solution at around 4.5.


Monopotassium phosphate is a fully water-soluble mono-potassium phosphate fertilizer, a highly efficient source of phosphorus and potassium for plants.
As a nitrogen-free fertilizer, Monopotassium phosphate is the preferred source of phosphorus and potassium when nitrogen fertilization should be limited.
For example, early in the growing season, when phosphorus and potassium are needed at high rates for the establishment of root system,


Application at the productive stages of sugar-rich fruit crops helps to increase sugar content and to improve the quality of these.
Application of Monopotassium phosphate reduces premature flower dropping and fruit shedding.
Monopotassium phosphate gives a significant increase in yield when sprayed at the time of flowering, fruit formation, and grain filling stages.
Monopotassium phosphate also improves the quality of the produce.


Monopotassium phosphate contains high quality macro and essential nutrients and chloride free ingredients.
Monopotassium phosphate can be applied to the crop by fertigation or through foliar spraying.
Monopotassium phosphate is fine crystalline powder which dissolves quickly in water without any residues.
Monopotassium phosphate is generally immediately available in most volumes.


Monopotassium phosphate, MKP, (also potassium dihydrogen phosphate, KDP, or monobasic potassium phosphate), KH2PO4, is a soluble salt of potassium and the dihydrogen phosphate ion which is used as a fertilizer, a food additive and a fungicide.
Monopotassium phosphate is a source of phosphorus and potassium.
Monopotassium phosphate is also a buffering agent


Monopotassium Phosphate, an eco-friendly fertilizer makes for strong roots when your plants need it most.
Monopotassium Phosphate is also a critical source of nutrition for sugar-rich foods such as fruits who experience an increased sugar content leading to a fresh, ripe and delicious harvest.
Monopotassium phosphate is a derivative of Phosphoric Acid.


Monopotassium phosphate is soluble in water.
Monopotassium phosphate is a white crystalline powder with a melting point of 252oC.
Monopotassium phosphate should be stored in tightly closed containers in a Room Temperature.
Monopotassium phosphate, the most concentrated straight fertilizer with phosphorus.


Monopotassium phosphate is a high purity product, totally soluble in water and fast dissolving.
Monopotassium phosphate is the most concentrated straight fertilizer containing phosphorus.
Monopotassium phosphate is Fully soluble P and K for all fertigated crops under drip irrigation, sprinkler systems, pivots or jets.
Monopotassium phosphate is a fully soluble fertilizer.


Monopotassium phosphate does not contain nitrogen and is low in sodium, which makes sure the product does not curdle.
Monopotassium phosphate contributes to the plant's transport and creation of sugars, starch and acids.
Monopotassium phosphate increases the fruit's quality and preservability and stimulates the growth of the root's and fruit's.
In addition, the transport of energy in the plant's cell is handled and the elements in the fertilizer contribute to the building blocks for cell walls.


Monopotassium phosphate, MKP, (also potassium dihydrogenphosphate, KDP, or monobasic potassium phosphate), KH2PO4, is a soluble salt of potassium and the dihydrogen phosphate ion.
Monopotassium phosphate is a source of phosphorus and potassium as well as a buffering agent.
Monopotassium phosphate (also potassium dihydrogen phosphate, KDP, or monobasic potassium phosphate, MKP) — KH2PO4 — is a soluble salt which is used as a fertilizer, a food additive and a fungicide.


Monopotassium phosphate is a source of phosphorus and potassium.
Monopotassium phosphate Is a source of phosphorus and potassium and is also a buffering agent.
A buffering agent helps to stabilize PH.
Phosphorus is an essential to the process of photosynthesis and is involved in the production of all oils, starches and sugars.


Both stress reducer as well as maturation facilitator phosphorus affects rapid growth while boosting flower and root development.
Potassium is responsible for water loss and absorption as well as the ability to endure colder temperatures.
Potassium is also necessary in the formation of sugars, starches and carbohydrates needed for protein synthesis and cell division.
Potassium aids in protein formation, photosynthesis, fruit/flower quality, and disease reduction.



USES and APPLICATIONS of MONOPOTASSIUM PHOSPHATE:
A notable utilization of Monopotassium Phosphate is as an ingredient in sports drinks like Gatorade and Powerade.
Monopotassium Phosphate is vastly used as a crystal for its non-linear optical properties.
Monopotassium phosphate applied in optical modulators and for non-linear optics like a second harmonic generation.
Monopotassium phosphate can be used for open field fertigation, greenhouses, foliar application and as a raw material for different fertilizers.


Monopotassium Phosphate is one of the most vastly used compounds in the agricultural industry.
Since Monopotassium phosphate is freely soluble in water it is very easy to use in the field.
Monopotassium Phosphate is commercially available at a very cheap rate and the farmers can buy this for agriculture.
Monopotassium Phosphate is used in the preparation of sodium phosphates, ammonium phosphates, calcium phosphates and other phosphates.
Monopotassium phosphate is also used in eggs, low sodium products, meat products and milk products for colour preservation.


Monopotassium phosphate maybe used to produce flurescence emmisionin carbon dots, buffers, pH control agent, emulsifier, stabilizer, water retention agent, antioxidant in foods.
Monopotassium phosphate can be used in fertilizer mixtures to reduce escape of ammonia by keeping pH low.
Used in buffers (determination of pH, pharmaceutical production, urinary acidifier, paper processing, baking powder, and food), nutrient solutions, yeast foods, special liquid fertilizers, sonar systems and other electronic applications.


Used as a nutritional supplement in foods, a nonlinear optical material for laser use, and in wastewater treatment.
Used to provide a source soluble source of potassium and phosphorus.
Used in Agriculture and as buffering agent.
Monopotassium phosphate contains no such hazardous elements such as chlorine, sodium or heavy metals, Monopotassium phosphate can be applied safely to all kinds of products.


It is demonstrated that Monopotassium phosphate fertilizer application via leaves prevents fungi growth.
When mixed with pesticides it is shown that Monopotassium phosphate increases the effectiveness of such pesticides.
Application of Monopotassium phosphate at the productive stages of sugar-rich fruit crops helps to increase sugar content and to improve the quality of these.
Monopotassium phosphate is often used as a nutrient source in the greenhouse trade and in hydroponics.


Monopotassium phosphate can be applied in combination with other fertilizers to meet crop nutritional needs throughout the growth cycle. -Monopotassium phosphate's high purity and water-solubility make Monopotassium phosphate an ideal fertilizer for Nutrigation (Fertigation) and for foliar application.
Monopotassium phosphate is suitable for preparation of fertilizer blends and production of liquid fertilizers.
Monopotassium phosphate can be used in fertilizer mixtures to reduce escape of ammonia by keeping pH low.


Monopotassium phosphate is used in nonlinear frequency conversion of laser light instead of protonated (regular) KDP due to the fact that the replacement of protons with deuterons in the crystal shifts the third overtone of the strong OH molecular stretch to longer wavelengths, moving it mostly out of the range of the fundamental line at approximately 1064 nm of neodymium-based lasers.
Regular KDP has absorbances at this wavelength of approximately 4.7–6.3% per cm of thickness while highly deuterated KDP has absorbances of typically less than 0.8% per cm.


As a crystal, Monopotassium phosphate is noted for Monopotassium phosphate's non-linear optical properties.
Used in optical modulators and for non-linear optics such as second-harmonic generation (SHG).
Monopotassium phosphate is used as an ingredient in sports drinks such as Gatorade and Powerade.
In medicine, monopotassium phosphate is used for phosphate substitution in hypophosphatemia.
Used as analysis reagent, pH buffer.


Used for the preparation of buffer, determination of arsenic, antimony, phosphorus, aluminum and iron I preparation of phosphorus standard solution and haploid breeding medium, determination of serum inorganic phosphorus, alkaline acid enzyme activity, preparation of bacterial serum test Leptospira medium and the like.
Monopotassium Phosphate is also used for the generation of harmonics of piezoelectric elements, electro-optical elements and laser light.
Monopotassium phosphate can be used in fertilizer mixtures to reduce escape of ammonia by keeping pH low.


Monopotassium Phosphate (MKP) is used in preparation of high solids clay slurries.
Used for Industrial use for preparing chemical mixtures
Used for Professional preparation of fertiliser products
Used for Professional use as farm fertiliser: loading and spreading.
Used for Professional use as fertiliser in greenhouses.


Used for Professional use as fertiliser, maintenance of equipment.
Together with dipotassium phosphate (K2HPO4.(H2O)x) Monopotassium phosphate is often used as a fertilizer, food additive, and buffering agent.
Monopotassium phosphate often cocrystallizes with the dipotassium salt as well as with phosphoric acid.
Single crystals are paraelectric at room temperature.
At temperatures below −150 °C (−238 °F), they become ferroelectric.


Used for Professional use as liquid fertiliser in the open field (e.g. fertigation).
Used in the production of fertilizer mixtures,
Used for fertilizing agricultural, fruit and gardening crops,
Used under cover and in field areas.
Monopotassium phosphate is used during the early stages of plant growth.


Monopotassium phosphate is used in the production of fertilizer mixtures and directly as a fertilizer.
Monopotassium phosphate's main use is fertigation and foliar fertilization of agricultural, orchard and horticultural crops both under cover and in the field.
Monopotassium phosphate called phosphorous-potassium fertilizer, is used to create liquid fertilizers and multi-component solid fertilizer mixtures.


Monopotassium phosphate is best used during the early stages of plant growth.
Monopotassium phosphate is also used to compose liquid fertilizers and solid multi-component fertilizer mixtures.
Monopotassium phosphate is used as a buffering agent, fertiliser and as a fungicide.
Used for Agricultural chemicals (non-pesticidal), Corrosion inhibitors and anti-scaling agents, Intermediates, Paint additives and coating additives not described by other categories, Plating agents and surface treating agents, Adhesives and Sealants,


Used for Agricultural Products, Building and Construction Materials, Lawn and Garden Care Products, Paints and Coatings, Photographic Supplies, Film, and Photochemicals
Monopotassium phosphate is widely used as a buffering agent for the determination of PH value
Monopotassium phosphate is also used as a food additive and as a fungicide
Monopotassium phosphate when used with urea and ammonium phosphates, helps to capture ammonia gas in soil, by keeping PH level low


Monopotassium phosphate is a rich source of phosphorous and potassium
Used for industrial use, water treatment, enzyme process, several animal feed, buffering agents in several pharmaceutical process, higher agriculture grade fertilizers, and other uses, as well as we manufacture
Used to all pharmaceutical, AR, Indian Pharmacopoeia, British Pharmacopoeia, United States Pharmacopoeia, Food, Animal Feed, Seafood and laboratory reagent grade standards.


Monopotassium phosphate is used for fertilising aquatic plants in an aquarium.
Monopotassium phosphate, also known as MKP, is a fertiliser used to provide phosphorus and potassium for plants.
Monopotassium phosphate is the basis of many fertilisers and is very soluble in water.
Along with monopotassium phosphate, potassium sulphate and potassium nitrate are also used.


Used as a fertilizer because it contains potassium and phosphate that can be applied to both the soil and foliage.
Used in the manufacture of sodium phosphates, ammonium phosphates, calcium phosphates and other phosphates.
For colour preservation, Monopotassium phosphate is used in eggs and is also used in low-sodium products, meat products and milk products.
Monopotassium phosphate is suited to application through all fertigation systems hydroponics, drip systems, low throw sprinklers, centre pivots and spray units.


Monopotassium phosphate, otherwise known as MKP is a product synonymous with fruit production that is widely used, primarily as a flower boosting green fruit supporter.
Monopotassium phosphate is used because of its weakly acidic salt, buffer capacity, and nutrient source capability.
Monopotassium phosphate (or MKP) is used in the Feed, but also used in the food fertilizer, ceramic and also being used as a flame-retardant.
Used in Feed, Food, Ceramic, Fertilizer.


Monopotassium Phosphate (MKP) can be applied in combination with other fertilizers, to meet crop nutritional needs throughout the growth cycle.
Monopotassium phosphate's high purity and water-solubility make Monopotassium phosphate an ideal fertilizer for fertigation and for foliar application.
Monopotassium Phosphate (MKP) is suitable for preparation of fertilizer blends and production of liquid fertilizers.
When applied as foliar spray, Monopotassium Phosphate (MKP) acts as a suppressor of powdery mildew.


Stimulating plants to develop buds; promote the differentiation of flowering, high flowering, high fruiting rate; limit the loss of young flowers and fruits; Rice flowering in bulk, anti-choking.
Helps quickly transport nutrients to fruits, tubers and seeds; increase the sweetness of fruit trees; increase starch content for tubers and rice plants; extend storage time.
Increased tolerance (cold, drought, alum ...); resistance to pests and diseases


Monopotassium Phosphate (KH2PO4) also known as potassium dihydrogenphosphate is an inorganic compound that is often used as a fertilizer, food additive, and buffering agent.
Used in Canned Fish, Processed Meats, Sausages & Ham, Baked Goods, Canned & Dried Vegetables, Chewing Gum, Candy, Crackers, Cereal, Fruit Juices, Dairy Products, Seasonings, Soft Drinks, pH Adjuster, Cosmetic Products
Used in agriculture: Phosphate rich and potassium rich, suitable for fertilizing plants in the period of flowering and fruit set.


Monopotassium phosphate (MKP) is a potential option for fertigating phosphorus (P) in potato (Solanum tuberosum L.) when petioles are low in P and high in nitrogen (N); which is a situation where using ammonium polyphosphate (APP) could potentially result in excessive N application.
Monopotassium phosphate has a number of uses across both manufacturing, industrial and horticultural including use in fertilisers, corrosion inhibitors and anti-scaling agents, paints, adhesives, sealants and coatings, intermediates and surface treatment agents.
Used in microbial fermentation in the production of MSG, bread yeast; used as micro-fertilizer, ...


Used in Raw materials for fertilizer production.
Monopotassium phosphate is suitable for use on any growing medium through irrigation systems and can be used for foliar spraying when rapid response is needed.
Monopotassium phosphate is suitable for use primarily in mangoes and cashews before flowering. Often useful for groundnuts, soya beans, and vegetables.


Monopotassium phosphate contains Phosphate and ultra-high Potassium in an easy-to-absorb form that helps plant growth; hard, against falling; flowering concentrates, fruit setting evenly.
Helps seedlings to develop strong roots, resist root choking; increase water and nutrient absorption; helps plants recover quickly after planting or is flooded, drought, organic poisoning.
Potassium salt of Phosphoric Acid (P359200), used in various chemical processes as a phosphorylating compound.


Monopotassium phosphate can be applied in combination with other fertilizers to meet crop nutritional needs throughout the growth cycle. -Monopotassium phosphate's high purity and water-solubility make Maxi MKP an ideal fertilizer for fFertigation and for foliar application.
Monopotassium phosphate is a completely soluble fertilizer consisting of potassium and phosphorus, recommended for vegetables, berries, vines, flowers, turf and ornamentals.


Used in the preparation of prosthetics and collagen nanocomposites due to the bone-like properties. pH buffer.
Monopotassium Phosphate is used as a thickener, emulsifier, sequestrant, acidity regulator, humectant and stabilizer.
Monopotassium phosphate is used in dessert mixes, pasteurized processed cheese, cheese spreads, jelly products, cheese foods, non diary powdered coffee creams and sauces, vitamin waters and energy drinks.


Used in Fertilizer production to keep the pH at a lower level
Monopotassium Phosphate (MKP) is used in sports beverages, coffee creamers, processed cheese and for fortification.
Monopotassium phosphate is also used in water soluble fertilizer applications as a great source of potassium and phosphorous nutrients for healthy plant life.
Monopotassium phosphate can be used in fertilizer mixtures to reduce escape of ammonia by keeping pH low.


Monopotassium phosphate can be used as a source of phosphorus and potassium when a pure product is needed in the fertilizer scheme.
Monopotassium phosphate can be added to the scheme without any risk for extra chloride, sodium and heavy metals.
Thanks to the low amount of sodium (less than 300 ppm), Monopotassium phosphate can be used in soil and substrate, but also in hydroculture.
Monopotassium phosphate is suitable to be mixed with many crop protection products and has a buffering function for the liquid in the tank.


Monopotassium phosphate is used to provide a high source of potassium and phosphorous in a water soluble form.
Commonly used as part of a feeding program in an ‘A’ and ‘B’ tank system in greenhouse production.
Monopotassium phosphate can also be used in field agriculture situations.
Monopotassium phosphate can be used as a source of high quality phosphorus and potassium.


Used For fertigated greenhouses, vegetables, fruits and flowers in any growing medium, as well as in open fields and orchards.
Monopotassium phosphate is Highly efficient source of soluble P and K for soluble NPK's and liquid fertilizers.
Monopotassium phosphate is Ideal for foliar application, having a triple action: Feeding of the plants.
Biopesticide: Monopotassium phosphate is fungicidal agent for disease control (especially powdery mildew disease).


Monopotassium phosphate is pH buffering of the spray solution.
With Monopotassium phosphate's low salt index, mono potassium phosphate is recommended for use in any type of crop and fertigation system: drip irrigation, hydroponics, sprinklers, pivots, or foliar spray.
Used in Agricultural Chemicals, Agriculture Intermediates, Animal Nutrition & Feed, Crop Protection, Food & Beverage, Food Additives, Household, Industrial & Institutional Chemicals, Oil Field Services, Pesticides


Used inAgriculture & Animal Care, Chemical & Materials Manufacturing, Food & Beverage, HI&I - Household, Industrial & Institutional, Oil & Gas
Monopotassium phosphate is fertilizer for hydroponics, fertigation, foliar nutrition and special starters.
Used in buffers (determination of pH, pharmaceutical production, urinary acidifier, paper processing, baking powder, and food), nutrient solutions, yeast foods, special liquid fertilizers, sonar systems and other electronic applications.
Used as a nutritional supplement in foods, a nonlinear optical material for laser use and in wastewater treatment.


Monopotassium phosphate is used as a Fertilizer.
Monopotassium phosphate is also used in Pulp & Paper Processing; Textiles; Metal Treatment Industry & in Buffers for determination of pH.
Monopotassium phosphate is suited to application through all fertigation systems – hydroponics, drip systems, low throw sprinklers, centre pivots and spray units.
Monopotassium phosphate has an ideal pH value of 5 (±0,5) to improve the spraying liquid and efficiency of the crop protection products.



SYNTHESIS AND MANUFACTURING PROCESS of MONOPOTASSIUM PHOSPHATE:
The major raw material to all the phosphates is Phosphoric Acid. Phosphoric Acid is manufactured from Rock Phosphate.
Phosphate rock is fed to a series of reactors along with recycled phosphoric acid from the process.
The phosphoric acid-fluoroapatite slurry is mixed with sulphuric acid which is added to the reactor series as a leaching agent.
After completing the reaction series, the process stream is washed with evaporator condensate while being forced through a filter.
The filter cake is composed primarily of gypsum (CaSO4 2H2O).
The Phosphoric Acid is concentrated to 75-100% by a series of evaporators and then cooled.
Monopotassium phosphate is manufactured by taking a reaction between Potassium Hydroxide (KOH) and phosphoric acid (H3PO4).
The resulting slurry of Monopotassium phosphate is solidified in a granulator.



BENEFITS of MONOPOTASSIUM PHOSPHATE:
-Suitable for all crops
-Improves luster, uniform color, and taste
-Since P and K are specially structured and designed, this will give excellent growth in all the stages of the crop namely seedling stage, vegetative stage, reproductive stage, and ripening stage
-Since pesticides and fungicides are very compatible with this product, all pesticides and fungicides can be mixed when applying Monopotassium phosphate.
-Monopotassium phosphate helps in the development of the roots.
Helps develop flowering in crops
-Monopotassium phosphate is a completely water-soluble fertilizer that provides readily available potassium and phosphorus.
-Monopotassium phosphate is free from toxic elements for plants such as chloride, sodium etc.
-Monopotassium phosphate is healthy for plants and human consumption.
-Monopotassium phosphate is the most readily available source of potassium and phosphorus fertilizer.
-Highly-concentrated source of both Phosphorus and Potassium for plants
-Ideal for application at reproductive (fruit setting) stage of fruit crops. -Increases sugar content thereby quality of fruits
-Suitable for both foliar spraying and drip irrigation
-Low salt content prevents clogging of drip system



DIRECTIONS for USE of MONOPOTASSIUM PHOSPHATE:
Monopotassium phosphate is one of the most used straight fertilizers in tailor made crop recommendations.
The high content level of Phosphorus and Potassium makes the product very flexible to be used in hydroponics matching easily the plant’s needs for these nutrients.
Recommended dilution rate = 10-15 kg / 100 liter. (100-150 grams / 1 Litre)



DIFFERENT KINDS of FOOD CONTAINS MONOPOTASSIUM PHOSPHATE AS FOOD ADDITIVES:
Monopotassium phosphate is derived from potassium phosphate which is a solvent salt that is frequently utilized as a fertilizer, a food additive, and fungicide.
Monopotassium phosphate is white/colorless in the form of crystalline granule or powder.
Monopotassium phosphate is mainly used as an ingredient in emulsifying salts for processed cheese products, and a component in Gatorade and meat products.

Monopotassium phosphate consists of the dietary minerals potassium and phosphorus in the form of phosphate.
Monopotassium Phosphate is used as a source of potassium (which is an electrolyte) and as a preservative.
Monopotassium phosphate in the food industry is used as food additives to stabilize and control food’s acidity and moisture.
Monopotassium phosphate's buffer properties allow pH value to be stabilized, the ionic strength of food to be improved, and the adhesion of water to the food holding ability to be increased.

Monopotassium phosphate is also widely used in the manufacture of flavoring agents, fermentation additives, baked goods, yeast food, and nutritional fortifiers.
Food additives are chemical that helps in preserving flavor or taste, appearance, or other qualities of food.
For centuries, certain additives have been used; for example, the preservation of food with pickling, bacon, salting, and preserving sweets or using sulfur dioxide as with wines.

In the second half of the 20th century, with the introduction of processed foods, many more natural and artificial additives were discovered.
Monopotassium phosphate effectively maintains and improves the shelf life of processed foods.
Monopotassium phosphate is an additive commonly found in dairy products, frozen meals, fruit juices, canned fish, cereal, soup, and vegetables.
Generally speaking any processed food including fast food might contain a phosphate additive such as monopotassium phosphate.
Below are different kind of foods that use monopotassium phosphate as food additives:

-Dairy Products:
The use of monopotassium phosphate varies in dairy products varies in different continental regions.
The use of additives is becoming more frequent in dairy products such as plain milk, whey, cream, and yogurt.

-Frozen Meals:
Frozen meals preserve food products from the time it is cooked till the time that is finally consumed.
The use of monopotassium phosphate in frozen meals is needed to prevent the degradation of the food.

-Fruits and Vegetables:
Food additives play an important role in fruits and vegetable processing to ensure the quality and safety of the product.
During fruit processing, a number of food additives were added to preserve and enhance the taste of the fruits.

-Cereal:
The role of food additives is to enrich foods with nutrients.
In quantities not higher than found in the food before processing, nutrients are added.
Cereal foods are a great example of an enriched food for preservation.



ADVANTAGES of MONOPOTASSIUM PHOSPHATE:
-Improves root and shoot growth
-Limits vegetative growth as of fruit setting
-Developed for fertigation in open field and greenhouses.
Also suitable for foliar application
-Low on heavy metals
-Low on Sodium and Chloride
-Easy to handle, dissolve and apply
-Fully water-soluble
-Consists of 100% plant nutrients
-Free of chloride, sodium and other detrimental elements for plants
-Safe for plants and humans: has a moderately low pH and low salt index
-Suitable for the Nutrigation, foliar application and fertilizer blends
-Very low salt index.
-Free of chlorine, sodium and impurities, make the product very safe for foliar applications
-Monopotassium phosphate exerts a buffering effect which tends to stabilize the pH of the nutritive solutions.
-The absence of Nitrogen in Monopotassium phosphate permits application of the most appropriate ratio of P:K for different stages: rooting, flowering, fruit set or ripening and harvest, stages where lower level of Nitrogen is required.
-Very pure free-flowing due to unique production process
-Maximum flexibility in use of Nitrogen
-Maximum content-safety
-Plant supporter when foliar applied
-No ammonia; the best fit for hydroponic growing systems
-Ideal for open-field fertigation
-Great crop starter, flower initiation
-Ideal tank buffer
-Monopotassium phosphate has a guaranteed nutrient content of 85,5 points of P and K.
This makes Monopotassium phosphate a very concentrated product.
Due to the unique production process of Monopotassium phosphate 0,5% SO4 is part of the formulation which keeps Monopotassium phosphate always and unconditionally free-flowing.
-When using Monopotassium phosphate the flexibility is high.
Monopotassium phosphate can be used in combination with any Nitrogen-containing fertilizer.
There is optimum freedom to choose the ideal fertigation program for the crops that are grown.
-Monopotassium phosphate is very safe.
Monopotassium phosphate does not contain chlorides, sodium or relevant heavy metals.
-Fully water-soluble
-Consists of 100% plant nutrients
-Free of chloride, sodium and other detrimental elements for plants
Safe for plants and humans: has a moderately low pH and low salt index
-Suitable for the fertigation, foliar application and production of fertilizer blends and nutrient solutions
-Monopotassium phosphate (MKP) is a widely used phosphorus and potassium fertiliser for plants, Monopotassium phosphate results in optimal flower production, root growth and nutrient uptake of plants.
-Fully Water Soluble
-Instant uptake of nutrients by the plants resulting in significant and quick improvement in crop will be seen
-Free of chloride, sodium and other detrimental elements for plants
-Through this application, nutrient uptake efficiency will be enhanced as losses due to leaching volatilization will be minimized
-Since P and K are specially structured and designed, this will give an excellent growth in all the stages of crop namely seedling stage, vegetative stage, reproductive stage and ripening stage
-The nutrients are textured and cohesively balanced.
Hence, this will give better result and excellent yield in all crops like fruits, vegetables, flowers, field crops, foliage crops etc.



MONOPOTASSIUM PHOSPHATE AS FOLIAR SPRAY:
Foliar application of Monopotassium Phosphate is an optional supplement to soil fertilization at growth stages when high levels of phosphorus and potassium are required.
At early season foliar application with Monopotassium Phosphate promotes the establishment of healthy root system.
Monopotassium Phosphate is an efficient suppressor of powdery mildew in susceptible crops (deciduous, vineyards, mango, cucumbers, melons, roses and others).
Application of 1% Monopotassium Phosphate mixed with systemic fungicides improves the efficiency and enable to reduce application rates of the latter.
On young leaves, spray concentration of 1.0% Monopotassium Phosphate is recommended in most crops.
On mature leaves and more tolerant crops, concentration of 2.0% may be applied.



PRODUCTION PROCESS of MONOPOTASSIUM PHOSPHATE:
There are many production methods of Monopotassium Phosphate, which can be summarized as neutralization method, extraction method, ion exchange method, double decomposition method, direct method, crystallization method and electrolysis method.
The production process of neutralization method, followed by organic extraction, double decomposition method, ion exchange method.

-neutralization method:
A 30% solution of caustic potash or potassium carbonate is sent to a neutralizer and neutralized with 50% phosphoric acid solution under stirring at a temperature of 80-100 °c and a pH of 4-5, the neutralized product is obtained by filtration, concentration, cooling crystallization, centrifugal separation and drying, and the crystallization mother liquor is returned to the concentration section for reuse.
The process flow of producing potassium dihydrogen phosphate by neutralization method's chemical reaction formula is:
H3PO4 +KOH = KH2PO4 + H2O
2H3PO4 +K2CO3=2KH2PO4 + H2O + CO2↑
Features: short process flow, mature technology, less equipment, high product quality, low energy consumption, less investment.
The method uses thermal phosphoric acid and potash as raw materials, which has high production cost and is difficult to apply in agriculture.
It is mainly used for the production of food, medicine and industrial grade potassium dihydrogen phosphate, but there is no other way to shake the dominance of its products in the food industry.
At present, the national production capacity of neutralized potassium dihydrogen phosphate accounts for more than 90% of the total production capacity.

-extraction method:
Organic extraction method and inorganic extraction method, the current industrial method for the organic extraction method.
The organic extraction method is a method for preparing potassium dihydrogen phosphate by selectively using an organic solvent for extraction and separation according to the characteristic that the organic solvent has different solubilities for different compounds.
It is in the presence of a suitable organic solvent (S), through the reaction of potassium chloride and phosphoric acid, the generated hydrochloric acid is almost extracted into the organic solvent, potassium dihydrogen phosphate is crystallized from the aqueous phase, washed and dried to obtain the product potassium dihydrogen phosphate, and the mother liquor is recycled after separation.
Hydrochloric acid is back-extracted from the organic phase by the stripping agent, and the extracting agent is recycled in the process.

-ion exchange method:
K + is adsorbed from the solution by potassium chloride solution through styrene cation exchange resin, and then the ammonium dihydrogen phosphate solution is replaced by the resin to prepare potassium dihydrogen phosphate solution, which is then concentrated, after cooling crystallization, centrifugal separation and drying, the finished potassium dihydrogen phosphate is obtained, and the crystallization mother liquor is returned to the concentration section for reuse.



TECHNICAL REQUIREMENTS of MONOPOTASSIUM PHOSPHATE:
-project industrial agriculture:
first-class product
Potassium dihydrogen phosphate (KH2PO4 on dry basis) content,% ≥ 98.0 97.0 96.0 92.0
Moisture content,% ≤ 2.5 3.0 4.0 5.0
PH 4.3-4.7 4.3-4.7
Water-insoluble matter content,% ≤ 0.20 0.50 -
Chloride (Cl) content,% ≤ 0.20 -
Iron (Fe) content% ≤ 0.003
Arsenic (As) content,% ≤ 0.005
Heavy metal (Pb) content,% ≤ 0.005
Potassium chloride (K2O on dry basis) content,% ≥ 33.9 33.5 33.2 31.8

-Food additive potassium dihydrogen phosphate:
project indicators
Food Grade
Potassium dihydrogen phosphate (KH2PO4 on dry basis) content,% ≥ 98.0
Loss on drying content% ≤ 1.0
Water-insoluble matter content,% ≤ 0.2
Arsenic (As) content,% ≤ 0.0003
Heavy metal (Pb) content,% ≤ 0.002
Fluoride (in F) content,% ≤ 0.001
Lead (in terms of Pb) content,% ≤ 0.0005



APPLICATION METHOD of MONOPOTASSIUM PHOSPHATE:
Monopotassium phosphate fertilizer is suitable for application via leaves.
As pH value of water used via sprinkler systems can be maintained at around 4,5, thanks to Monopotassium phosphate fertilizer absorption of all major and trace elements is facilitated.
Thanks to low EC value (0,7 mS/cm) risks for burns in leaves are too low and therefore it may even be used in high concentrations.
Monopotassium phosphate may be mixed with any soluble fertilizer; yet should not be used together with fertilizers containing calcium (Ca).



STRUCTURE of MONOPOTASSIUM PHOSPHATE:
Monopotassium phosphate can exist in several polymorphs.
At room temperature Monopotassium phosphate forms paraelectric crystals with tetragonal symmetry.
Upon cooling to −150 °C (−238 °F) it transforms to a ferroelectric phase of orthorhombic symmetry, and the transition temperature shifts up to −50 °C (−58 °F) when hydrogen is replaced by deuterium.
Heating to 190 °C (374 °F) changes Monopotassium phosphate's structure to monoclinic.
When heated further, Monopotassium phosphate decomposes, by loss of water, to potassium metaphosphate, KPO3, at 400 °C (752 °F).

There is a huge possibility of the existence of Monopotassium Phosphate in several polymorphs.
Paraelectric crystals with tetragonal symmetry are formed by the compound at room temperature.
If cooling is done up to -150 degree C (-238 degree F) Monopotassium phosphate converts to a ferroelectric phase of orthorhombic symmetry.
If hydrogen is replaced by deuterium then the transition temperature shifts up to -50 degree C (-58 degree F).
The structure of the Monopotassium Phosphate is changed to monoclinic if the substance is heated up to 190 degree Celcius (374 degree F).
If the heat is increased further then Monopotassium Phosphate decomposes because of the loss of water and turns into potassium metaphosphate (KPO3) at 400 degree Celcius (752 degree F).



APPLICATION RATE of MONOPOTASSIUM PHOSPHATE:
Deciduous Fruits (including apples, pears, cherries, prunes, apricots, peaches, plums and nectarines):
Apply 5 to 10 lbs. per acre per application.
Apply as pre-bloom and post-bloom sprays.
Note (for pears):
When daytime temperatures are expected to exceed 90°F. Do not apply more than 8 lbs. per acre.

-Precautions:
Keep a minimum of 7 days between application.
Do NOT apply to crops under stress.
With rising temperatures (a.m.) stop spraying at 84°F.
Falling temperatures (p.m.) start spraying at 90°F.
Under certain conditions, including handgun application, Monopotassium Phosphate can cause leaf injury.
To reduce chances of foliage injury be sure to obtain enough gallonage with dilute sprays to cause runoff (350 GPA).
Use correct gallonage with concentrate sprays to avoid a runoff and excessive dripping on the tree.
Be sure to avoid over spraying when treating young or dwarf trees.
Comments on gallonage are based on spray volume being applied on full size trees.
Proper spray calibration is important to reduce chances of injury.

-Field Crops (Foliar Application):
*Alfalfa, Clover:
Use 2 to 8 lbs. per acre per application.
First application at 6 to 8 inches, repeat applications to new growth after each cutting.

*Almonds:
Make 3 to 4 applications per season at a rate of 5 to 10 lbs. per acre in sufficient volume for thorough coverage.
Make first application at petal fall and continue at 30 day intervals until hull split.

*Beans (including dry, succulent and limas):
Use 5 to 10 lbs. per acre.
Apply when plant leaves are large enough to absorb a foliar nutrient or from bud set to early bloom.
*Carrots, Beets, Sweet Potatoes and Other Vegetable Root Crops:
Use 5 to 10 lbs. per acre per application.

*Citrus:
First, dilute spray.
Use 3 to 5 lbs. per 100 gallons, not to exceed a total of 15 lbs. per acre per application.
In concentrate sprays or aerial application, use 5 to 10 lbs. per acre in 15 to 150 gallons per acre.

*Grapes:
Apply at 3 to 10 lbs. per acre per application when leaves first appear.
Repeat application as necessary.
An application pre-bloom and post-bloom are suggested if needed.
Apply 10 lbs. per acre within 30 days of harvest to increase solids.

*Strawberries:
Apply 3 to 10 lbs. per acre shortly after first blooms appear.
Repeat applications as necessary during growing season to improve berry size and quality.
*Hops:
Begin application at early season training and continue through the end of bloom period as often as every 7 days.

*Corn (Field and Sweet):
Use 5 to 10 lbs. per acre per application.
*Cotton:
Use 5 to 10 lbs. per acre per application as needed, starting at squaring (pre-bloom).

*Legumes (peas (dry and succulent), lentils, garbanzos):
Apply 2 to 8 lbs. per acre in sufficient water to cover by ground or by air.
Apply when plant leaves are large enough to absorb a foliar nutrient up through mid-bloom stage.
*Celery, Cole Crops, and Leafy Vegetables:
Use 1 to 2 lbs. per acre per application.

*Lettuce:
Use 1 to 5 lbs. per acre.
Make several applications at intervals of 10 to 14 days starting at thinning or after transplanting.
Use multiple low rates instead of high rate applications.

*Melons, Cucumbers, and Other Cucurbits:
Use 5 to 10 lbs. per acre per application.
Make two or more applications starting just prior to bloom.

*Mint:
Use 2 to 10 lbs. per acre per application.
*Onions (dry and green):
*Garlic:
Use 5 to 10 lbs. per acre per application.

*Pistachios:
Make 3 to 4 applications per season at a rate of 5 to 10 lbs. per acre in sufficient volume for thorough coverage.
Make first application immediately post bloom and repeat as necessary until hull split.

*Potatoes:
Use 5 to 10 lbs. per acre.
Apply at initial tuber formation.
Subsequent applications may be made with various fungicide and/ or insecticide cover sprays.
Consult your local Agricultural Consultant for specific recommendations.

*Small Grains (wheat, barley, and oats):
Use 2 to 6 lbs. per acre in sufficient water to cover by air or by ground.
Apply at tillering, but before early boot stage.

*Sugar Beets:
Use 5 to 10 lbs. per acre.
Apply when leaves are 10” across.
Repeat 3 to 4 weeks later.

*Tomatoes (Fresh) and Peppers:
Use 5 to 10 lbs. per acre per application in a minimum of 20 gallons of water per acre by ground.
Do not exceed 5 lbs. per acre in 10 gallons of water by air.
Two to three applications are advised at two to three week intervals, starting immediately prior to full bloom, two weeks later and finally at early fruiting stage.

*Tomatoes (Processing):
Apply 2 to 3 applications at 5 to 10 lbs. per acre in a minimum of 20 gallons of water per acre by ground.
Do not exceed 5 lbs. in 10 gallons of water per acre by air.
The first application should be made immediately prior to full bloom, two weeks later and finally at early fruit sizing.

*Walnuts:
Make 2 to 3 applications in rates of 5 to 10 lbs. per acre in sufficient volume for thorough coverage.
Make first application at an early set and repeat at 3 to 4-week intervals until June 15th.



PHARMACODYNAMICS of MONOPOTASSIUM PHOSPHATE:
Potassium is the major cation of intracellular fluid and is essential for maintenance of acid-base balance, isotonicity, and electrodynamic characteristics of the cell.
Potassium is an important activator in many enzymatic reactions and is essential to a number of physiologic processes including transmission of nerve impulses; contraction of cardiac, smooth, and skeletal muscles; gastric secretion; renal function; tissue synthesis; and carbohydrate metabolism.
Phosphate is a major intracellular anion that participates in providing energy for metabolism of substrates and contributes to important metabolic and enzymatic reactions in almost all organs and tissues.
Phosphate exerts a modifying influence on calcium concentrations, a buffering effect on acid-base equilibrium, and has a major role in the renal excretion of hydrogen ions.



MECHANISM of ACTION of MONOPOTASSIUM PHOSPHATE:
The bulk of the body's phosphorus is located in the bones, where it plays a key role in osteoblastic and osteoclastic activities.
Enzymatically catalyzed phosphate-transfer reactions are numerous and vital in the metabolism of carbohydrate, lipid and protein, and a proper concentration of the anion is of primary importance in assuring an orderly biochemical sequence.
ln addition, phosphorus plays an important role in modifying steady-state tissue concentrations of calcium.
Phosphate ions are important buffers of the intracellular fluid, and also play a primary role in the renal excretion of the hydrogen ion.
Oral administration of inorganic phosphates increases serum phosphate levels.
Phosphates lower urinary calcium levels in idiopathic hypercalciuria.



ABSORPTION of MONOPOTASSIUM PHOSPHATE:
Potassium salts are well absorbed from the GI tract.
Ingested phosphates are absorbed from the gastrointestinal tract.
However, the presence of large amounts of calcium or aluminum may lead to formation of insoluble phosphate and reduce the net absorption.
Vitamin D stimulates phosphate absorption.



PRODUCTION METHOD of MONOPOTASSIUM PHOSPHATE:
-phosphoric acid double decomposition method:
The hydrogen chloride gas produced by the metathesis reaction with saturated potassium chloride solution and excess 120 phosphoric acid at 130 ~ 75% ℃ is absorbed with water to produce by-product hydrochloric acid.
Then the excess phosphoric acid is neutralized with potassium hydroxide, control end point for the pH value of 4.2~4.6.
Finally, cooling and washing, centrifugal separation, drying products, mother liquor can be reused.

-Neutralization method:
With constant stirring, the caustic potash is mixed into a solution with a relative density of 1.3 (about 30%) and neutralized with 50% phosphoric acid.
The reaction temperature is maintained at 85~100 ° C, the terminal pH value is controlled at 4.2~4.6 (Congo red test paper is light purple).
The neutralized liquid is concentrated to the relative density of 1.32~1.33 and filtered, then cooled to 36 ° C:
The following crystals, centrifugal separation, the product is dried and the mother liquor can be reused.
Potassium carbonate can also be used for neutralization, and the process is similar to the above.
KOH+H3PO4→KH2PO4+H2O

-industrial production methods include neutralization method, double decomposition method, extraction method, electrodialysis method, ion exchange method, etc.:
Double decomposition method of 30% sodium hydroxide solution with distilled water in the reactor, under stirring slowly add 85% Phosphoric acid neutralization reaction.
The solution is neutralized to pH 4.1~4.3, prepared sodium dihydrogen phosphate
Then add 90% potassium chloride at about 100 ° C for double decomposition reaction, and keep the heat for half an hour to reach equilibrium, add arsenic removal agent and heavy metal removal agent for solution purification, filtration, remove arsenic and heavy metals and other impurities, the filtrate is cooled to normal temperature, add phosphoric acid with arsenic removal to adjust Ph 4.4~4.7, adjust the relative density to 31~32 °C with water, stir for 30 min, the crystals were precipitated and separated by centrifugation to prepare a finished product of potassium dihydrogen phosphate for feed.
Its NaH2PO4+KCl→KH2PO4+NaCl
When the mother liquor was evaporated to 108-109 °C., the liquid was turned from clear to white, and sodium chloride crystals were obtained, which were removed by filtration.
The filtrate was returned to the procedure for use.

-Caustic potash method:
An iron-removing caustic potash solution (about 30% KOH) was added to an enamel reactor with a stirring and steam jacket, and an appropriate amount of phosphoric acid (diluted to 50% H3PO4) was added slowly with stirring.
The neutralization reaction is carried out, the reaction temperature is maintained at 85~100 ℃, the pH value is controlled at 4.2~4.6, and the relative density of the solution at the end of the reaction is 1.32~1.33.

After evaporation and concentration to the relative density of 1.38~1.42, sent to the crystallization process, cooled to 36 deg C below the precipitation of crystals, and then separated dehydration, washing, drying, prepared potassium dihydrogen phosphate.
Its KOH+H3PO4→KH2PO4+H2O
Potassium chloride method 95% potassium chloride is dissolved in 70~80 ° C hot water, adjusted to a solution close to saturation, and 75% phosphoric acid is added to the reactor according to the ratio of KCl:H3PO4 = 1:1.2, the neutralization reaction was carried out at 150 to 170°C.

To produce potassium dihydrogen phosphate and hydrogen chloride. The hydrogen chloride was recovered as hydrochloric acid by cooling.
Dilute potassium hydroxide solution was added to the reaction solution for neutralization, and the end point was controlled at about pH 4.6 ~.
After evaporation and concentration, cooling crystallization, centrifugal separation, proper water washing and drying, the potassium dihydrogen phosphate product was obtained.
Its H3P04+KCl→KH2PO4+HCl↑
The mother liquor contains a large amount of potassium dihydrogen phosphate, potassium chloride and free acid, and is returned to the process ingredients for use.

-The neutralization method:
It is industrially used, and is produced by the neutralization method of caustic potash phosphoric acid and the neutralization method of potassium chloride phosphoric acid.
Caustic potash method see potassium dihydrogen phosphate, increase in arsenic removal agent and removal of heavy metals in solution purification, filtration, removal of arsenic and heavy metals and other impurities in the process.

Slowly add the calculated amount of potassium hydroxide solution in phosphoric acid neutralization reaction to generate potassium dihydrogen phosphate solution, and then after decolorization, filtration, concentration, cooling, precipitation crystallization, and then centrifugal separation, drying to give the finished product.
Phosphoric acid was added to water, and potassium hydroxide or potassium carbonate was added thereto.
The filtrate was concentrated to a relative density of 1.32 by heating and filtration.
Cooling, suction and filtration out of the crystal, that is, potassium dihydrogen phosphate.



HOW TO DOSE MONOPOTASSIUM PHOSPHATE IN YOUR PLANTED AQUARIUM?
Expect an increase of 0.1ppm PO4 per every 6.94 milligrams (equivalent to less than 1/64 tsp) KH2PO4 added to your 10gal aquarium to yield:
PO4 0.1ppm
P 0.03ppm
K 0.08ppm



PHYSICAL and CHEMICAL PROPERTIES of MONOPOTASSIUM PHOSPHATE:
Molar mass: 136.086 g/mol
Appearance: White powder, deliquescent
Odor: Odorless
Density: 338 g/cm3
Melting point: 252.6 °C (486.7 °F; 525.8 K)
Boiling point: 400 °C (752 °F; 673 K) , decomposes
Solubility in water: 22.6 g/100 mL (20 °C) 83.5 g/100 mL (90 °C)
Solubility: Slightly soluble in ethanol
Acidity (pKa): 6.86
Basicity (pKb): 11.9
Refractive index (nD): 1.4864

Appearance Form: powder
Color: white
Odor: odorless
Odor Threshold: Not applicable
pH: 4,2 - 4,6 at 20,0 g/l at 20,0 °C
Melting point/range: 252,6 °C
Initial boiling point and boiling range: 450 °C at 1.013 hPa
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): No data available

Upper/lower flammability or explosive limits: No data available
Vapor pressure: < 0,1 hPa at 25 °C
Vapor density: No data available
Relative density: 2,33 at 21,5 °C
Water solubility: 208 g/l at 20 °C completely soluble
Partition coefficient: n-octanol/water: Not applicable for inorganic substances
Molecular Weight: 136.086
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0

Exact Mass: 135.93277702
Monoisotopic Mass: 135.93277702
Topological Polar Surface Area: 80.6 Ų
Heavy Atom Count: 6
Formal Charge: 0
Complexity: 61.9
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2

Compound Is Canonicalized: Yes
Molecular Weight: 136.1
Appearance: White fine Powder
PH Range (1% w/v): 4.0 – 5.0
Assay % (minimum): 97.00
P2O5 content % (minimum): 51.00
‘K’ Content % (minimum): 27.00
Iron as ‘Fe’ content %: 0.02
Chloride as ‘Cl’ content %: 0.2
Sulfate as ‘SO4’ content %: 0.03

Appearance: Crystalline solid
Vapor pressure: Less than 1 mm Hg
Odor: Odorless
Vapor density: Not applicable
Odor Threshold: No information
Density 2.34 g / cm3 at 20 ° C
pH (1% aqueous solution) 4.2 – 4.8
Solubility: in water: high
Melting point / freezing point: 253 ° C
Partition coefficient: noctanol / water: Not applicable, substance inorganic

Initial boiling point and boiling range:
400 °C loses water and turns into metaphosphate
Auto-ignition temperature: Not applicable
Flash point: Not applicable
Decomposition temperature: Decomposition does not occur below 600 °C
Evaporation rate: No information
Viscosity: Not applicable, solid
Flammability (solid, gas): Non-flammable
Explosive properties: Does not show
Oxidizing properties: Does not meet the criteria as an oxidiser



FIRST AID MEASURES of MONOPOTASSIUM PHOSPHATE:
-After inhalation:
Fresh air.
-In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
-After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
-After swallowing:
Make victim drink water (two glasses at most).



ACCIDENTAL RELEASE MEASURES of MONOPOTASSIUM PHOSPHATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of MONOPOTASSIUM PHOSPHATE:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of MONOPOTASSIUM PHOSPHATE:
-Control parameters:
*Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses.
*Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of MONOPOTASSIUM PHOSPHATE:
-Storage conditions:
Tightly closed.
Dry.
Keep in a dry place.



STABILITY and REACTIVITY of MONOPOTASSIUM PHOSPHATE:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



SYNONYMS:
Potassium dihydrogenphosphate
Potassium dihydrogen(tetraoxidophosphate)(1−)
Potassium dihydroxidodioxidophosphate(1−)
Potassium phosphate monobasic;
Phosphoric acid, monopotassium salt;
Potassium biphosphate
Potassium dihydrogen phosphate
7778-77-0
Potassium phosphate monobasic
MONOPOTASSIUM PHOSPHATE
Monobasic potassium phosphate
Potassium acid phosphate
Potassium phosphate, monobasic
Monopotassiumphosphate
Phosphoric acid, monopotassium salt
Potassium dihydrogen orthophosphate
Monopotassium monophosphate
Monopotassium orthophosphate
Monopotassium dihydrogen phosphate
Potassium dihydrogenorthophosphate
potassium biphosphate
potassium dihydrogenphosphate
potassium;dihydrogen phosphate
Sorensen's potassium phosphate
Potassium phosphate (K(H2PO4))
KH2PO4
Orthophosphoric acid, monopotassium salt
CHEBI:63036
MFCD00011401
4J9FJ0HL51
MKP
Monopotassium dihydrogen monophosphate
Monopotassium dihydrogen orthophosphate
Phosphoric acid, potassium salt (1:1)
Potassium phosphate monobasic (anhydrous)
Chlorine Titrimeter Reagent
Buffer Solution, pH 6.00
Buffer Solution, pH 7.00
Buffer Solution, pH 7.40
MFCD00147253
Potassium dihydrogen orthophosphate(V)
HSDB 5046
Buffer Solution, pH 7.00, Color-Coded Yellow
Potassium orthophosphate, dihydrogen
EINECS 231-913-4
EPA Pesticide Chemical Code 076413
Potassium hydrogen phosphate (KH2PO4)
UNII-4J9FJ0HL51
Potassium phosphate, monobasic
mono potassium phosphate
mono-potassium phosphate
EC 231-913-4
Potassium phosphate,monobasic
potassium di-hydrogen phosphate
CHEMBL1200925
DTXSID0035667
INS NO.340(I)
UNII-B7862WZ632
INS-340(I)
POTASSIUM PHOSPHATE
Potassium Dihydrogen Phosphate,(S)
EINECS 240-213-8
BDBM50004328
AKOS015902364
AKOS028109678
B7862WZ632
DB09413
Phosphoric acid, potassium salt (1:?)
Potassium phosphate, monobasic (JAN/NF)
E-340(I)
Potassium dihydrogen phosphate, Puratronic?
B7291
FT-0645117
MONOBASIC POTASSIUM PHOSPHATE
POTASSIUM PHOSPHATE, MONOBASIC
D02050
Potassium phosphate monobasic, Trace metals grade
Q415049
POTASSIUM DIHYDROGEN PHOSPHATE
Potassium phosphate, 0.2M buffer solution, pH 7.0
Potassium phosphate, 0.2M buffer solution, pH 7.2
Potassium phosphate, 0.2M buffer solution, pH 7.4
Potassium phosphate, 0.2M buffer solution, pH 7.5
Potassium phosphate, 0.2M buffer solution, pH 7.6
Potassium phosphate, 0.5M buffer solution, pH 7.0
Potassium phosphate, 0.5M buffer solution, pH 7.4
Potassium phosphate, 0.5M buffer solution, pH 7.5
Potassium phosphate, 0.5M buffer solution, pH 7.6
POTASSIUM PHOSPHATE, MONOBASIC [ORANGE BOOK]
TIS-U-SOL COMPONENT POTASSIUM PHOSPHATE, MONOBASIC
Potassium phosphate monobasic powder suitable for cell culture
POTASSIUM PHOSPHATE, MONOBASIC COMPONENT OF TIS-U-SOL
POTASSIUM PHOSPHATES COMPONENT MONOBASIC POTASSIUM PHOSPHATE
MONOBASIC POTASSIUM PHOSPHATE COMPONENT OF POTASSIUM PHOSPHATES
Buffer solution, pH 1.68 (+/-0.01 at 25?C), No Color, Specpure, NIST Traceable
MKP
PHOSPHATE LOW NO 1
PHOSPHATE LOW NO 2
MONOPOTASSIUM PHOSPHATE
Mono Potassium Phosphate
PHOSPHATE STANDARD SOLUTION
Potassium Phosphate Monobasic
Potassium dihydrogen phosphate
Potassium phosphate, monobasic
Dipotassium dihydrogenphosphate
potassium dihydrogenorthophosphate
Phosphoric acid, monopotassium salt
Potassium Phosphate, Monobasic, Molecular Biology Grade
Potassium dihydrogen phosphate anhydrous 99.995 Suprapur
Potassium dihydrogen phosphate cryst.
Monopotassium dihydrogen phosphate
Monopotassium monophosphate
Monopotassium orthophosphate
Monopotassium phosphate
Orthophosphoric acid, monopotassium salt
Phosphoric acid, monopotassium salt
Phosphoric acid, potassium salt (1:1)
Potassium acid phosphate
Potassium dihydrogen orthophosphate
Potassium dihydrogen phosphate
Potassium phosphate
Potassium phosphate monobasic
MONOPROPYLENE GLYCOL
Monopropylene glycol is a specific raw material used by manufacturers of green cosmetic products.
Monopropylene glycol is a synthetic compound in the chemical group called 1,2 glycol.
Monopropylene glycol is a clear, slightly viscous, colorless, odorless liquid and soluble in water.

CAS Number: 5343-92-0
EC Number: 226-285-3
Molecular Formula (Monopropylene glycol): C5H12O2
Molecular Weight: 104.15 g/mol

Synonyms: 1,2-Pentanediol, Pentane-1,2-diol, 1,2-Dihydroxypentane, 5343-92-0, Pylethylene Glycol, glycol, Glycol, Green Protector, 1,2-Dihydroxypentane, MFCD00010736, 1,a2-aPentanediol, EINECS 226-285-3, BRN 1719151, AI3-03317, NSC 513, 108340-61-0, ACMC-20mbh5, ACMC-1AXDB, EC 226-285-3, 1,2-Pentanediol, 96%, SCHEMBL62155, 3-01-00-02191 (Beilstein Handbook Reference), 1,2-Pentanediol, (2R)-, NSC513, WCVRQHFDJLLWFE-UHFFFAOYSA-, DTXSID10863522, NSC-513, AKOS009156977, AS-40006, SY032914, CS-0017222, FT-0606477, FT-0690841, P1178, 3-(2-NITRO-PHENYL)-ISOXAZOL-5-YLAMINE, 98484-EP2372017A1, A829586, Q3374899

Monopropylene glycol is a synthetic compound that belongs to the chemical group called 1,2 glycol.
Monopropylene glycol is a transparent liquid, slightly viscous, colorless, odorless and soluble in water as well as oil.

Monopropylene glycol is naturally derived from sugar cane.
Monopropylene glycol is used in many cosmetic products.
Monopropylene glycol is also referred to by the names 1,2- dihydroxypentane, 1,2-pentanediol, and pentane-1,2-diol.

Monopropylene glycol is a natural polyhydric alcohol and therefore has the ability to bind water.
This property can be used to moisturize the skin.

Skin is better hydrated, looks significantly brighter and feels better.
At the same time, Monopropylene glycol naturally helps inhibit the growth of microorganisms on the skin and can therefore be used as an alternative preservative.

Monopropylene glycol is soluble in water, acts as an extractant and solvent, is biodegradable, can be used in the pH range of 3-10, and is colorless and odorless.
Monopropylene glycol is made from natural sugar cane bagasse and is therefore ideal for natural cosmetics.

Monopropylene glycol is a specific raw material used by manufacturers of green cosmetic products.
The most important feature of this preservative is that Monopropylene glycol is obtained from agricultural products. For example, corn and sugar cane.
Monopropylene glycol is also commonly called Pentylene glycol.

Monopropylene glycol is a synthetic compound in the chemical group called 1,2 glycol.
There are two alcohol groups attached to the 1st and 2nd carbon.

Monopropylene glycol is a clear, slightly viscous, colorless, odorless liquid and soluble in water.
Monopropylene glycol is also obtained naturally from sugar cane.
Monopropylene glycol is also fat-soluble and used in many cosmetic products.

Monopropylene glycol is a natural diol derived from sugar cane bagasse's remaining waste, but a cheap synthetic analog also available in the market.
This multifunctional ingredient is a colorless, odorless, slightly viscous liquid that serves as a moisturizer, solubilizer, preservative, emulsion stabilizer, etc.

Monopropylene glycol is a well-known moisturizer due to the humectant properties of the molecule, proven scientifically by in-vivo studies.
Also, Monopropylene glycol is an excellent solubilizer, as Monopropylene glycol helps to solubilize many challenging ingredients, including fragrances.
Monopropylene glycol can also increase the clarity of translucent formulations like aqueous gels and toners.

Monopropylene glycol protects products from harmful bacteria and improves shelf-life, working synergistically with many preservatives, boosting their efficacy and thus helping to reduce their dose.
In addition, Pentane-1,2-diol stabilizes formulations, especially oil-in-water emulsions (as a co-emulsifier with an HLB value of 8.4), which helps reduce the particle size of emulsions, thus providing less coalescence and better stability.

This diol enhances the bioavailability of other ingredients (proven by ex-vivo study), boosting the activity of both lipophilic and hydrophilic actives.
Furthermore, Monopropylene glycol improves pigment distribution, makes whiter and shinier emulsions, promotes penetration into the skin, and improves the efficiency of cooling agents.

Incorporated in sun care applications, Monopropylene glycol enhances water resistance and the entire safety of the formula used even in SPF 50+ products.
Monopropylene glycol also can control the viscosity and texture of the final product.
In skin and hair care products and decorative cosmetics, Monopropylene glycol concentration can reach up to 5%.

Monopropylene glycol is used in formulations as an emulsion stabilizer, solvent and a broad spectrum antimicrobial.
Monopropylene glycol also helps moisturize and has a light, elegant feel to it.

Monopropylene glycol will leave the skin soft and smooth.
Monopropylene glycol can help to solubilize and stabilize lipophilic ingredients in aqueous solutions.

Monopropylene glycol shows a broad spectrum antimicrobial activity against yeasts, moulds, and bacteria.
Monopropylene glycol disturbs the integrity of microbial cell membranes, a mechanism of action that is unlikely to be affected by resistance.

Being a non-ionic ingredient, the anti-microbial effect of Monopropylene glycol is largely pH-independent.
Monopropylene glycol can act as a standalone antimicrobial protection agent.

In addition, Monopropylene glycol can be easily combined with other classical or non-classical antimicrobial agents, to boost their preservation effects.
Monopropylene glycol a synthetic, low molecular weight solvent and skin-conditioning agent.

Monopropylene glycol is commonly used as a skin conditioning agent, due to Monopropylene glycol (1,2 pentanediol)’s ability to help the skin attract and retain moisture.
As such, Monopropylene glycol falls into a category of skin care ingredients called humectants.

Monopropylene glycol is synthetic humectant used in cosmetics and beauty products that is also secondarily used as a solvent and preservative.
Monopropylene glycol is both water and oil-soluble and Monopropylene glycol can have moisture-binding and Monopropylene glycol can have antimicrobial properties.

Monopropylene glycol also has some anti microbial properties, which can make Monopropylene glycol a valuable addition to products that are susceptible to contamination of microorganisms.
Monopropylene glycol is used as a solvent in chemicals produced to soften and smooth the skin in the cosmetic industry.

Monopropylene glycol is used in sunscreens.
Monopropylene glycol is a skin moisturizer.

Monopropylene glycol preserves moisture in the skin, helps to preserve elasticity and moisture of the skin.
Pethylene glycol has an antimicrobial effect.
Pethylene glycol Lipid and dissolved lipophilic actives can be used in penetration enhancing creams and lotions.

Pethylene glycol Hydrogenated phosphotidylcholine is a high viscosity base composed of protected lipids and glycerol.
Monopropylene glycol is an antimicrobial, chemically produced emulsifier.

Pentilen Glycol has been included in the German Pharmaceutical Codex since 2009.
However, Monopropylene glycol is not only approved in Germany, but Monopropylene glycol is also approved as a cosmetic active ingredient worldwide.

Monopropylene glycol is initially based on the immature juice of sugar beets, while synthetic production is standard.
Monopropylene glycol is used in day and night creams.

Monopropylene glycol is a complex system for paraben esters-free cosmetic and personal care products.
Monopropylene glycol is a multifunctional agent that has excellent efficacy as a biostatic and fungistatic agent.
Monopropylene glycol can reduce irritation and sensitivity and has a wide broad-spectrum antimicrobial effect.

Monopropylene glycol is an ingredient which is found naturally in some plants (such as sugar beets and corn cobs) but is most frequently lab-derived when used in cosmetics.
Monopropylene glycol is a humectant, meaning it binds well to water, making Monopropylene glycol a good hydrating agent and solvent to aid penetration of other ingredients.
Monopropylene glycol also helps improve the texture of skin care formulas and has mild preservative properties when used in amounts between 1-5%.

There have been some reports that Monopropylene glycol (along with other glycols) is a skin sensitizer; however, as with many ingredients, the amount and how it’s used are key.

Monopropylene glycol is a chemical compound commonly used in the cosmetics and personal care industry as a skincare and beauty product ingredient.
Monopropylene glycol is also known by its chemical formula C5H12O2.
Monopropylene glycol is a type of glycol, which is a class of organic compounds that contain multiple hydroxyl (OH) groups.

Monopropylene glycol proves multifunctional in skincare and cosmetic formulations, offering a spectrum of benefits.
With its hydrating properties, Monopropylene glycol serves as an effective moisturizer, aiding in maintaining skin moisture levels, particularly beneficial for individuals with dry or dehydrated skin.

Acting as a solvent, Monopropylene glycol ensures a consistent and uniform texture in products by dissolving other ingredients.
Monopropylene glycol antimicrobial properties contribute to its role as a preservative, preventing the growth of bacteria and fungi and enhancing Monopropylene glycol's longevity.

Recognized for Monopropylene glycol mild and non-irritating nature, Monopropylene glycol is considered suitable for sensitive skin.
Additionally, Monopropylene glycol facilitates the penetration of active ingredients, amplifying the efficacy of skincare formulations.
Overall, Monopropylene glycol is a versatile ingredient, addressing various aspects of skincare, from hydration and preservation to compatibility with different skin types.

Monopropylene glycol is generally recognized as safe for use in cosmetics and skincare products when used in accordance with regulations and guidelines.
However, as with any ingredient, individual reactions or sensitivities may vary, so it's essential to check Monopropylene glycol's ingredients list and perform a patch test if you have sensitive skin or allergies.

Uses of Monopropylene glycol:
Monopropylene glycol is used as an emulsion stabilizer, humectant, solvent and a broad-spectrum antimicrobial.
Monopropylene glycol improves texture of the product.

Monopropylene glycol has all the characteristics of a solvent.
Monopropylene glycol is not reactive and can dissolve many other compounds.

Monopropylene glycol is also known to have antimicrobial properties.

Monopropylene glycol offers a double advantage:
Monopropylene glycol protects the skin from harmful bacteria, which could otherwise cause body odor and acne problems on the skin.
Secondly, Monopropylene glycol protects the product from any microbial growth, so Monopropylene glycol can show the same quality during its use and shelf life.

Skin care:
Due to the two -OH groups, Monopropylene glycol has a natural tendency to attract water.
Monopropylene glycol also retains water, which is especially helpful for dry skin.

Monopropylene glycol is used as a humectant and skin conditioning agent, for Monopropylene glycol ability to retain moisture.
Monopropylene glycol is used in moisturizer, baby sunscreen, around-eye cream, antiperspirant/deodorant, serums & essences, hand cream, anti-aging, facial moisturizer/treatment, detanning products, bath oil/salts/soak, body oil, body firming lotion, cuticle treatment, body wash/cleanser, tanning oil, recreational sunscreen

Hair care:
Monopropylene glycol is used in various hair care products such as hair treatment/serum, hair spray, hair styling aide, shampoo, detangler, beard care, shaving cream, beard oil, conditioner, hair color and bleaching, styling gel/lotion, mask, setting powder/spray

Decorative cosmetics:
Monopropylene glycol is used in cosmetics such as lipstick, concealer, eye shadow, foundation, CC cream, blush, lip balm, facial powder, bronzer/highlighter, lip gloss, BB cream, makeup primer, brow liner, lip liner, eye liner, lip plumper, lip balm, makeup remover

Uses Area of Monopropylene glycol:
Monopropylene glycol is used as a solvent in chemicals produced in the cosmetic industry to soften and smooth the skin.
Monopropylene glycol has a softening and smoothing effect in this area of use.

Monopropylene glycol is used together with steroidal hormones in the manufacture of dermatological products.
In these applications, 1,3-butylene glycol and Mono Pentylene glycol are also used as solvents.

This is because 1,3-butylene glycol and Mono Pentylene glycol do not have completely toxic effects.
Monopropylene glycol is used by combining anti-inflammatory hydrocortisone with Pentylene glycol to relieve minor skin irritation, temporary itching and inflammation.

Monopropylene glycol is used in the production of allergy medications.
Monopropylene glycol has antimicrobial properties because Monopropylene glycol is Dihydric Alcohol.

Monopropylene glycol helps prevent unwanted microorganisms due to Monopropylene glycol antimicrobial effect.
Monopropylene glycol is preferred in the production of quality cosmetic products because Monopropylene glycol allergic effects are very low.

Monopropylene glycol is used in the manufacture of daily skin care products due to Monopropylene glycol moisturizing effect on the skin.
By retaining water on the skin, Monopropylene glycol makes the skin more vibrant, smooth and plump.

Monopropylene glycol is used as a solvent in chemicals produced to soften and smooth the skin in the cosmetics industry.
Monopropylene glycol has a softening and smoothing effect in this area of ​​use.

Monopropylene glycol is used together with steroidal hormones in the manufacture of dermatological products.
In these applications, Monopropylene glycol and Mono Pentylene glycol are also used as solvents.

This is because Monopropylene glycol and Mono Pentylene glycol do not have exactly the toxic effects.
Monopropylene glycol is used to relieve minor skin irritation, temporary itching and inflammation, by combining the anti-inflammatory hydrocortisone with pylenylene glycol.

Monopropylene glycol is used in the production of allergy medicines.
Monopropylene glycol has antimicrobial properties due to being dihydric alcohol.
Due to Monopropylene glycol antimicrobial effect, Monopropylene glycol helps to prevent unwanted microorganisms.

Monopropylene glycol is preferred in the manufacture of quality cosmetic products because of Monopropylene glycol very low allergic effects.
Monopropylene glycol is used in the manufacture of daily skin care products due to its moisturizing effect on the skin.
By keeping the water on the skin, Monopropylene glycol makes the skin more lively, smooth and full.

Applications of Monopropylene glycol:
Monopropylene glycol has a wide range of applications.
Intermediate finds applications in Initial product for chemical syntheses, Inks and coatings, Plasticizers and Solvent, Industrial chemicals.

Monopropylene glycol is used as a plasticizer in cellulose products and adhesives.
Monopropylene glycol is used as a brake fluid additive.

Monopropylene glycol reacts with 3,4-dihydro-2H-pyran to get 5-tetrahydropyran-2-yloxy-pentan-1-ol.
Monopropylene glycol is also used to prepare polyesters for emulsifying agents and resin intermediates.

Monopropylene glycol is used in ink, toner and colorant products.
In addition to this, Monopropylene glycol is used in brake fluid compositions.

Monopropylene glycol is used to produce materials made of polyester or polyurethane, for the manufacturing of monomers, for the manufacture of polyester polyols, polycarbonatedioles and acrylic monomers, for the production of delta valerolactone and for molecules that act as reactive diluents, for the production of halogenated substances and for the production of adhesives, putties and sealing compounds, cleaners and auxiliary agents.
Monopropylene glycol is used in the processes to produce hydrogen, hydrogen peroxide, sodium perborate and peroxyacetic acid and as an intermediate for pharmaceutical products.
Monopropylene glycol is used as an ingredient for the production of polymeric thickeners, plasticizers for polyvinyl chloride, sizing agents, surfactants, for starches and chemically modified starch for application in the paper, textile and food industry, for personal hygiene products like shampoo, creams, and for paints.

Benefits of Monopropylene glycol:
Monopropylene glycol naturally tends to attract water because Monopropylene glycol has two -OH groups.
Monopropylene glycol also retains water, which is especially beneficial for dry skin.

Monopropylene glycol is used as a humidifier due to its moisture retention capacity.
Monopropylene glycol has all the properties of a solvent.

Monopropylene glycol is non-reactive and can dissolve many other compounds.
As mentioned before, due to Monopropylene glycol ability to naturally retain moisture in the skin, Monopropylene glycol also nourishes the skin and hair.

Monopropylene glycol is also known to have antimicrobial properties.
Monopropylene glycol offers a double advantage – Monopropylene glycol protects the skin from harmful bacteria that can otherwise cause body odor and acne problems on the skin.

Secondly, Monopropylene glycol protects the product from microbial growth, so that Monopropylene glycol can maintain the same quality throughout its use and shelf life.
Monopropylene glycol is used in the formulations of creams, lotions, moisturizers, cleansers and other skin care products.

Monopropylene glycol offers several benefits when used in skincare and cosmetic products:

Moisturization:
Monopropylene glycol helps to hydrate the skin by retaining moisture, making Monopropylene glycol beneficial for individuals with dry or dehydrated skin.

Solvent:
Monopropylene glycol serves as a solvent for various cosmetic ingredients, ensuring that the product has a uniform texture and consistency.

Preservation:
Monopropylene glycol has antimicrobial properties, which help prevent the growth of harmful microorganisms like bacteria and fungi in cosmetic products, extending their shelf life.

Skin-Friendly:
Monopropylene glycol is known for being mild and non-irritating, making Monopropylene glycol suitable for sensitive skin types and reducing the risk of skin irritation or allergic reactions.

Enhanced Ingredient Penetration:
Monopropylene glycol can improve the absorption of other active ingredients into the skin, increasing the effectiveness of skincare formulations.

Peoduction of Monopropylene glycol:
Monopropylene glycol is produced synthetically from corn and sugar cane.

Origin of Monopropylene glycol:
Monopropylene glycol is based on by-products from manufacturing processes based on sugarcane residues and corn spindles.
However, Monopropylene glycol is manufactured in the lab as the consumption is relatively high.

Effect of Monopropylene glycol in the formulation:
antimicrobial
Emulsion stabilization
Moisturizer
Solvent

Physical And Chemical Properties of Monopropylene glycol:
Monopropylene glycol is a physically colorless oil-free liquid.
The density of Monopropylene glycol is 0.994 g/mol.

The melting point of Monopropylene glycol is -18 °C.
Monopropylene glycol is a stable chemical.

Monopropylene glycol should be stored at room temperature.
Monopropylene glycol is soluble in water.

Safety profile of Monopropylene glycol:
Monopropylene glycol does not have any evidence to suggest hazardous to health, toxicity, or carcinogenicity.
Monopropylene glycol has been found to cause mild irritation to the eyes and skin in skin types that are already sensitized or prone to irritation.

Health Effect of Monopropylene glycol:
Monopropylene glycol is a semi-synthetic component.
The starting raw materials are of natural origin, but are transformed into a different form than their original state using various processes under laboratory conditions.
These are raw materials obtained without using animal sources (propolis, honey, beeswax, lanolin, collagen, snail extract, milk, etc.).

Monopropylene glycol is a criterion that should be taken into consideration for those who want to use vegan products.
Studies have concluded that different effects can be seen on each skin type.

For this reason, the allergy/irritation effect may vary from person to person.
However, Monopropylene glycol may cause reactions such as stinging, tingling, itching, redness, irritation, skin flaking and swelling, especially in people with sensitive skin types.

Identifiers of Monopropylene glycol:
CAS Number: 5343-92-0
Chem/IUPAC Name: 2-heptanoyloxypentyl heptanoate
EINECS/ELINCS No: 226-285-3
COSING REF No: 58983

Molecular Formula (Monopropylene glycol): C5H12O2
Molecular Weight: 104.15 g/mol
Chemical Name: 1,2-Pentanediol
CAS Number: 5343-92-0

Chemical Abstracts Service (CAS) Number: 57-55-6
European Inventory of Existing Commercial Chemical Substances (EINECS) Number: 200-338-0
Chemical Formula: C3H8O2
PubChem CID: 1030
ChemSpider ID: 995

Properties of Monopropylene glycol:
form: solution
mol wt: Mr ~1500
packaging: pkg of 10 × 4 mL
manufacturer/tradename: Roche
shipped in: wet ice
storage temp.: 2-8°C
SMILES string: C(CO)O
InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key: LYCAIKOWRPUZTN-UHFFFAOYSA-N

Physical State: Monopropylene glycol is a clear, colorless, odorless liquid at room temperature.
Solubility: Monopropylene glycol is miscible with water and many organic solvents, making it versatile for use in formulations.
Boiling Point: The boiling point of monopropylene glycol is around 188°C (370°F).
Density: The density of Monopropylene glycol is approximately 1.036 g/cm³ at 20°C.
Viscosity: Monopropylene glycol has a relatively low viscosity, which makes it easy to handle and incorporate into various products.
Hygroscopicity: Monopropylene glycol is hygroscopic, meaning it can absorb moisture from the air.
Chemical Stability: Monopropylene glycol is stable under normal conditions but can react with strong oxidizing agents.
Flammability: While not highly flammable, Monopropylene glycol is combustible and should be handled with appropriate precautions.
Taste and Odor: Monopropylene glycol has a slightly sweet taste and is odorless, making it suitable for use in food, pharmaceuticals, and cosmetics.

Other Names of Monopropylene glycol:

IUPAC Names:
1,5-Pentanediol
1,5-pentanediol
Pentamethylene glycol
pentane,-1,5-diol
Pentane-1,5-diol
pentane-1,5-diol
Pentane-1,5-diol
pentane-1,5-diol
Pentanediol
MONOPROPYLENE GLYCOL FOOD GRADE
DESCRIPTION:

Food grade Mono Propylene Glycol (MPG) is an additive coded E1520 which is used in the food industry at low doses as an emulsifier, particularly for the preparation of dishes, sauces or seasonings.
Monopropylene Glycol Food Grade is also used as a solvent in the preparation of certain flavourings.
Another more recent application is its use in the manufacture of liquid for electronic cigarettes as well as ice machines.

CAS 57-55-6

The quality of this food grade Monopropylene Glycol Food Grade meets the purity criteria of the USP/EP (United States Pharmacopeia/European Pharmacopoeia).
Monopropylene Glycol Food Grade, in technical version , is also a component of many products such as:
liquid detergents
coolant (industrial and commercial heating and cooling systems, heat pumps, etc.).
Monopropylene Glycol Food Grade will be used in antifreeze in food processing facilities in order to limit risks (HACCP).
hydraulic fluids
lubricants
solvent of organic compounds



Monopropylene Glycol Food Grade is Also known as MPG or Mono-Propylene Glycol.
Monopropylene Glycol Food Grade is Ideal for various food applications, floral waters, e-liquids, hair products, soap and skincare products.
Monopropylene Glycol Food Grade can also aid the bonding of oils and blends so that they perfectly combine in food applications.

Propylene Glycol is a colourless liquid that is added to foods, moisturising creams, lotions, bath salts and any other formulations to add additional moisturisation.
Monopropylene Glycol Food Grade is also added to skin and hair care products and soap making as a lubricant and preservative.

Monopropylene Glycol Food Grade is 99.9% pure (as pure as it gets).
Monopropylene Glycol Food Grade is Supplied in a tamper-evident container.
Monopropylene Glycol Food Grade is Suitable for Vegans, Vegetarians, Non-GMO. Gluten Free, Non-Irradiated, Kosher Friendly, Halal Friendly.

Monopropylene Glycol Food Grade is USP / EP premium quality pharma food grade
Monopropylene Glycol Food Grade Can be used in various food applications
Monopropylene Glycol Food Grade is Ideal for use in hair, soap, skincare products and e-liquid

Monopropylene Glycol Food Grade Aids in the bonding of oils and other blends
Monopropylene Glycol Food Grade is Suitable for Vegan's, Non-GMO. Gluten Free, Non-Irradiated. Kosher Friendly, Halal Friendly
Storage Conditions: Store in dry, cool conditions and not in direct sunlight. Use within 6 months of opening.



Monopropylene Glycol Food Grade is premium quality USP / EP pharma food grade.
Monopropylene Glycol Food Grade is Also known as MPG or Mono-Propylene Glycol.
Monopropylene Glycol Food Grade is Ideal for various food applications, floral waters, e-liquids, hair products, soap and skincare products.

Monopropylene Glycol Food Grade can also aid the bonding of oils and blends so that they perfectly combine in food applications.
Monopropylene Glycol Food Grade is a colourless liquid that is added to foods, moisturising creams, lotions, bath salts and any other formulations to add additional moisturisation.

Monopropylene Glycol Food Grade is also added to skin and hair care products and soap making as a lubricant and preservative.
Monopropylene Glycol Food Grade is 99.9% pure (as pure as it gets).
Monopropylene Glycol Food Grade is Supplied in a tamper-evident container.
Monopropylene Glycol Food Grade is Suitable for Vegans, Vegetarians, Non-GMO. Gluten Free, Non-Irradiated, Kosher Friendly, Halal Friendly.


Mono Propylene Glycol (MPG) serves as a solvent, connects and stabilises insoluble fluids, reduces the freezing point in water, increases the boiling point, and offers outstanding stability with high flash and boiling points.

Monopropylene Glycol Food Grade is chemically neutral, i.e. Monopropylene Glycol Food Grade usually does not react with other substances.
Monopropylene Glycol Food Grade is used as a humecant in food and cosmetics to maintain moisture levels in products.

These can include marshmallows, coconut flakes, shampoo and baby wipes along with many other products.
Monopropylene Glycol Food Grade is used as an antifreeze for various reasons, including as an engine coolant additive, home water pipes and food processing systems.

Because Monopropylene Glycol Food Grade is non toxic, Monopropylene Glycol Food Grade is safe to use in food applications where accidental ingestion may occur.
This gives MPG a huge advantage over other antifreezes.



USES OF MONOPROPYLENE GLYCOL FOOD GRADE

Monopropylene Glycol Food Grade can be an integral component in a variety of industries that is due to its relatively low toxicity.
To list, Monopropylene Glycol is used for the production of unsaturated polyester resins, creating bath tubs, small boats, chemical/water tanks and pipes.
Further applications include paints and coatings, aeroplane de-icers, antifreeze, coolants, detergents and hydraulic fluids.



United States Pharmacopoeia (USP) Grade MPG has a minimum purity of 99.8%.
Monopropylene Glycol Food Grade is a colourless, viscous, and odourless liquid.
Monopropylene Glycol Food Grade is highly hygroscopic and miscible in all ratios with water, alcohols, esters, ketones, and amines.

Monopropylene Glycol Food Grade has limited miscibility with halogenated hydrocarbons and is not miscible with aliphatic hydrocarbons.
USP grade Monopropylene Glycol Food Grade is used during the production of Food, Beverage, and Cosmetic/Personal Care Products.
Pharmaceutical Industries will use it as an excipient (inactive ingredient or carrier in a pharmaceutical product).

Usage in Antifreeze Coolant:
Fluid Science provides MPG Based Food Safe Antifreeze Coolant with 50/50 DI Water and MPG mix.
This can also be ordered in a bespoke ratio of Glycol and Water.
Manufacturers of Air Source Heat Pumps recommend the use of a Glycol Anti-Freeze to prevent it from freezing up during the winter months.

This will prevent any damage when water freezes and expands within the plate of the heat exchanger which could cause leaks and a broken heat pump.
As this water is used within homes/buildings and comes into contact with people, a food safe Glycol like Monopropylene Glycol is perfect for use in this matter.
We supply Monopropylene Glycol (MPG) on its own or within our very own Antifreeze Coolant mixture as “Ultra-Pure Grade”.



APPLICATIONS OF MONOPROPYLENE GLYCOL FOOD GRADE:
Monopropylene Glycol Food Grade is Used in the agricultural industry as a livestock drench.
Monopropylene Glycol Food Grade is used as Ingredient in herbal remedies and homeopathic applications.
Monopropylene Glycol Food Grade is A carrier in fragrance oil.


Monopropylene Glycol Food Grade is An emulsification agent in Angostura and orange bitters.
Monopropylene Glycol Food Grade is An ingredient in massage oils, in hand sanitizers, antibacterial lotions and saline solutions.
Monopropylene Glycol Food Grade is As a base for certain antifreeze preparations.


Monopropylene Glycol Food Grade is Direct food additive
Monopropylene Glycol Food Grade is Humectant and stabilizer in fruits, vegetables and bakery goods (except in Europe)

Monopropylene Glycol Food Grade is Indirect contact food applications
Monopropylene Glycol Food Grade has Low temperature heat-transfer fluid in the brewing, dairy and ice cream industries and for food storage facilities



CHEMICAL AND PHYSICAL PROPERTIES OF MONOPROPYLENE GLYCOL FOOD GRADE:
Color / Appearance transparent colorless liquid
Smell light odor
Density 1.035
Grade Food
N° CAS 57-55-6
Others SH 29053200


SAFETY INFORMATION ABOUT MONOPROPYLENE GLYCOL FOOD GRADE
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.



MONOSODIUM GLUTAMATE
MONOSODIUM GLUTAMATE; Glutamate de sodium; SODIUM GLUTAMATE, N° CAS : 142-47-2 / 6106-04-3 / 16177-21-2 / 32221-81-1 - Glutamate monosodique, Nom INCI : SODIUM GLUTAMATE, Nom chimique : Sodium hydrogen glutamate; N° EINECS/ELINCS : 205-538-1 / 240-313-1. Additif alimentaire : E621.Ses fonctions (INCI) : Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit. Agent d'entretien de la peau : Maintient la peau en bon état. Noms français : Glutamate de sodium; GLUTAMATE MONOSODIQUE; SODIUM, GLUTAMATE DE. Noms anglais : ALPHA-MONOSODIUM GLUTAMATE; GLUTAMIC ACID, MONOSODIUM SALT, L-; GLUTAMIC ACID, MONOSODIUM SALT, L-(+)-; L(+) SODIUM GLUTAMATE; L-GLUTAMIC ACID, MONOSODIUM SALT; L-GLUTAMIC ACID, SODIUM SALT; MONOSODIUM GLUTAMATE; MONOSODIUM L-GLUTAMATE; Sodium glutamate; SODIUM HYDROGEN GLUTAMATE. Utilisation et sources d'émission : Additif alimentaire
MONOSODIUM GLUTAMATE (MSG)

Monosodium glutamate, commonly known as MSG, is the sodium salt of glutamic acid, one of the most abundant naturally occurring non-essential amino acids.
Monosodium glutamate (MSG) is an amino acid that plays a crucial role in the taste of umami, one of the basic tastes alongside sweet, sour, bitter, and salty.

CAS Number: 6106-04-3
EC Number: 612-072-6

Monosodium glutamate, 6106-04-3, MSG, Sodium glutamate, Sodium L-glutamate, E621, L-Monosodium glutamate, Monosodium L-glutamate, L-Glutamic acid monosodium salt, Glutamic acid sodium salt, Sodium (2S)-2-aminopentanedioate, Monosodium DL-glutamate, 2-Aminopentanedioic acid monosodium salt, 2-Aminopentanedioic acid sodium salt, Sodium 2-aminopentanedioate, Acido glutamico monosodico, UNII-8ZHY70N48U, FEMA No. 2291, Glutamic acid, monosodium salt, L-Glutamic acid, sodium salt, Monosodium L-glutamate monohydrate, Sodium 2-aminopentanedioate monohydrate, Glutamic acid monosodium salt monohydrate, L-Glutamic acid sodium salt monohydrate, Monosodium DL-glutamate monohydrate, Monosodium 2-aminopentanedioate monohydrate, UNII-W81N5U6R6U, 2-Aminopentanedioic acid, monosodium salt, monohydrate, Acido glutamico, monosodico, monoidrato, Aji-no-moto, Natriumglutamat, Sodium glutamate monohydrate, Monosodium DL-glutamate monohydrate, (S)-2-Aminopentanedioic acid, monosodium salt, Sodium L-2-aminopentanedioate, 2-Aminopentanedioic acid, sodium salt, Sodium 2-aminopentanedioate monohydrate, 2-Aminopentanedioic acid sodium salt monohydrate, L-Glutamic acid monosodium salt monohydrate, Sodium L-glutamate monohydrate, Monosodium DL-glutamate monohydrate, Monosodium 2-aminopentanedioate monohydrate, Aji-no-moto, E621, L-Glutamic acid sodium salt monohydrate, L-Glutamic acid monosodium salt, Monosodium L-glutamate monohydrate, Sodium glutamate monohydrate, Monosodium DL-glutamate monohydrate, (S)-2-Aminopentanedioic acid, monosodium salt, Sodium L-2-aminopentanedioate, 2-Aminopentanedioic acid, sodium salt, Sodium 2-aminopentanedioate monohydrate, 2-Aminopentanedioic acid sodium salt monohydrate, L-Glutamic acid monosodium salt monohydrate, Sodium L-glutamate monohydrate, Monosodium DL-glutamate monohydrate, Monosodium 2-aminopentanedioate monohydrate, Ve-tsin, Vetsin, Flavor Enhancer 621, Accent, Ajinomoto, Aji-no-moto, E621, Glutacyl, Glutamic acid monosodium salt, Glutamate sodium, Glutamic acid sodium salt, Glutamate de sodium, L-Glutamic acid monosodium salt, Levoglutamide, Sodium glutamate, Sodium L-glutamate, Ve-tsin, Vetsin, Flavor Enhancer 621, Accent, Ajinomoto, Aji-no-moto, E621, Glutacyl, Glutamic acid monosodium salt, Glutamate sodium, Glutamic acid sodium salt, Glutamate de sodium, L-Glutamic acid monosodium salt, Levoglutamide, Sodium glutamate, Sodium L-glutamate, MSG, Monosodium glutamate, Sodium glutamate, 6106-04-3, Monosodium glutamate, Sodium glutamate, Sodium L-glutamate, E621, L-Monosodium glutamate, Monosodium L-glutamate, L-Glutamic acid monosodium salt, Glutamic acid sodium salt, Sodium (2S)-2-aminopentanedioate, Monosodium DL-glutamate, 2-Aminopentanedioic acid monosodium salt, 2-Aminopentanedioic acid sodium salt, Sodium 2-aminopentanedioate, Acido glutamico monosodico, UNII-8ZHY70N48U, FEMA No. 2291, Glutamic acid, monosodium salt, L-Glutamic acid, sodium salt, Monosodium L-glutamate monohydrate, Sodium 2-aminopentanedioate monohydrate, Glutamic acid monosodium salt monohydrate, L-Glutamic acid sodium salt monohydrate, Monosodium DL-glutamate monohydrate, Monosodium 2-aminopentanedioate monohydrate, UNII-W81N5U6R6U, 2-Aminopentanedioic acid, monosodium salt, monohydrate, Acido glutamico, monosodico, monoidrato, Aji-no-moto, Natriumglutamat, Sodium glutamate monohydrate, Monosodium DL-glutamate monohydrate, (S)-2-Aminopentanedioic acid, monosodium salt, Sodium L-2-aminopentanedioate, 2-Aminopentanedioic acid, sodium salt, Sodium 2-aminopentanedioate monohydrate, 2-Aminopentanedioic acid sodium salt monohydrate, L-Glutamic acid monosodium salt monohydrate, Sodium L-glutamate monohydrate, Monosodium DL-glutamate monohydrate, Monosodium 2-aminopentanedioate monohydrate, Aji-no-moto, E621, L-Glutamic acid sodium salt monohydrate, L-Glutamic acid monosodium salt, Monosodium L-glutamate monohydrate, Sodium glutamate monohydrate, Monosodium DL-glutamate monohydrate, (S)-2-Aminopentanedioic acid, monosodium salt, Sodium L-2-aminopentanedioate, 2-Aminopentanedioic acid, sodium salt, Sodium 2-aminopentanedioate monohydrate, 2-Aminopentanedioic acid sodium salt monohydrate, L-Glutamic acid monosodium salt monohydrate, Sodium L-glutamate monohydrate, Monosodium DL-glutamate monohydrate, Monosodium 2-aminopentanedioate monohydrate



APPLICATIONS


Monosodium glutamate (MSG) is frequently utilized in the creation of flavorful salad dressings, contributing to a well-balanced taste.
In the culinary world, Monosodium glutamate (MSG) is employed to enhance the flavor of pickled vegetables and olives.

Monosodium glutamate (MSG) finds its way into the production of savory condiments, enriching the taste of various sauces.
Monosodium glutamate (MSG) is often added to pre-seasoned rice and grain mixes to elevate their overall taste.

Monosodium glutamate (MSG) is incorporated into seasoned cracker and chip products, providing a savory and enjoyable snacking experience.
When creating savory dips, chefs may use Monosodium glutamate (MSG) to intensify the taste and make them more appealing.

Certain instant curry and stew mixes feature Monosodium glutamate (MSG) as a key component for enhanced flavor.
The umami taste of Monosodium glutamate (MSG) is utilized in the preparation of rich and flavorful risottos.

In the baking industry, Monosodium glutamate (MSG) may be added to certain savory bread and roll recipes to improve taste.
Monosodium glutamate (MSG) is sometimes included in the seasoning of pre-marinated meats, enhancing their succulence.

Specialty spice blends, such as those used in unique regional cuisines, may incorporate MSG for added depth.
When crafting savory spreads and pâtés, Monosodium glutamate (MSG) can contribute to a more complex and enjoyable taste.
In the production of seasoned nuts and trail mixes, Monosodium glutamate (MSG) can enhance the overall snacking experience.

Some seasoned seafood products, such as crab cakes and fish fillets, may contain MSG for flavor enhancement.
Monosodium glutamate (MSG) is used in the creation of savory gelatin-based dishes, adding a unique taste element.

Monosodium glutamate (MSG) is a component in certain specialty condiments, contributing to their distinctive and robust flavor.
In the realm of fusion cuisine, chefs may incorporate MSG to bridge and enhance diverse flavor profiles.

Monosodium glutamate (MSG) is used in the seasoning of savory pastry fillings to create a more satisfying taste.
Certain fermented foods, like kimchi, may utilize MSG to augment their umami taste.
Monosodium glutamate (MSG) is applied in the preparation of savory spreads for sandwiches and wraps, enhancing their flavor.

When making seasoned vegetable side dishes, chefs may use MSG to accentuate the natural tastes.
Monosodium glutamate (MSG) is found in some savory energy bars, contributing to a more enjoyable snack.
Certain savory gelato and ice cream creations may feature Monosodium glutamate (MSG) to add a unique depth of flavor.

Monosodium glutamate (MSG) can be utilized in the production of savory emulsions and sauces, enhancing their overall taste.
Chefs experimenting with molecular gastronomy may use MSG to create unique and intensified flavor experiences.


Monosodium glutamate (MSG) has several uses in different industries:

Frozen Entrees:
Monosodium glutamate (MSG) is commonly used in the production of frozen entrees to enhance the taste and aroma of the prepared dishes.

Ethnic Cuisine:
Found in various ethnic cuisines, Monosodium glutamate (MSG) plays a role in dishes ranging from Mexican to Middle Eastern.

Flavoring Rubs:
Monosodium glutamate (MSG) is added to spice rubs for meats, providing a savory and flavorful crust during cooking.

Flavored Tofu Products:
In the production of flavored tofu and plant-based protein products, Monosodium glutamate (MSG) can contribute to a more savory taste.

Gourmet Cooking:
Monosodium glutamate (MSG) is used in gourmet cooking to elevate the complexity and richness of high-end dishes.

Instant Soup Mixes:
Monosodium glutamate (MSG) is a common ingredient in instant soup mixes, providing a quick and satisfying flavor boost.

Prepared Sausages:
Monosodium glutamate (MSG) is often included in the seasoning of prepared sausages to enhance the overall taste.

Convenience Foods:
Monosodium glutamate (MSG) is found in a wide array of convenience foods, including microwavable meals and quick-prep items.

Potato Dishes:
Monosodium glutamate (MSG) is used in the preparation of potato dishes, such as mashed potatoes and seasoned fries.

Flavoring Egg Dishes:
Monosodium glutamate (MSG) can be incorporated into egg-based dishes like omelets and scrambled eggs for added savory notes.

Flavored Cooking Oils:
Some specialty cooking oils are infused with Monosodium glutamate (MSG) to provide a unique and enhanced flavor.

Vegetarian Gravy:
MSG is used in vegetarian gravy preparations to mimic the savory taste of traditional meat-based gravies.

Savory Crepes:
In savory crepe fillings, Monosodium glutamate (MSG) may be used to intensify the flavor of ingredients.

Flavoring Risotto Balls:
Chefs use Monosodium glutamate (MSG) to enhance the flavor of risotto balls, creating a more satisfying appetizer.

Flavoring Ethnic Stews:
In the preparation of ethnic stews, Monosodium glutamate (MSG) can contribute to a more authentic and enjoyable taste.

Savory Pancakes:
Monosodium glutamate (MSG) can be experimented with in savory pancake recipes to create a unique breakfast option.

Umami Burgers:
Some gourmet burger recipes may incorporate Monosodium glutamate (MSG) to enhance the umami taste of the patty.


In the seasoning of potato skins, Monosodium glutamate (MSG) can contribute to a more flavorful snack.
Monosodium glutamate (MSG) is often added to cooking broths for poaching and braising to enrich their flavor.
In the Southern cuisine, Monosodium glutamate (MSG) may be used in flavored grits for a more robust taste.

In certain culinary experiments, chefs use Monosodium glutamate (MSG) to add a savory note to pudding recipes.
MSG-infused herb butter is employed to add depth to dishes like roasted meats and vegetables.

In innovative culinary creations, Monosodium glutamate (MSG) may be used to enhance the taste of savory yogurt dishes.
Monosodium glutamate (MSG) is often found in recipes featuring mushrooms, as it complements their earthy flavor.



DESCRIPTION

Monosodium glutamate, commonly known as MSG, is the sodium salt of glutamic acid, one of the most abundant naturally occurring non-essential amino acids.
Monosodium glutamate (MSG) is an amino acid that plays a crucial role in the taste of umami, one of the basic tastes alongside sweet, sour, bitter, and salty.
Umami is often described as a savory or meaty flavor.

Monosodium glutamate (MSG) is a white crystalline powder with a fine texture.
Monosodium glutamate (MSG) has a characteristic savory and umami taste.
Monosodium glutamate (MSG) is water-soluble, making it easy to incorporate into various culinary applications.

Monosodium glutamate (MSG) is derived through the fermentation of starches or sugars, creating a natural source of glutamic acid.
Monosodium glutamate (MSG) intensifies and enhances the natural flavors of foods, adding depth and richness.

Monosodium glutamate (MSG) is stable at room temperature and exhibits good solubility in both hot and cold liquids.
Known for its ability to balance and round out taste profiles, Monosodium glutamate (MSG) is widely used in Asian cuisine.
Monosodium glutamate (MSG) is often employed to reduce the need for excessive salt in recipes while maintaining flavor.

Despite its controversial history, scientific studies generally support the safety of Monosodium glutamate (MSG) as a food additive.
Monosodium glutamate (MSG) is a common ingredient in processed foods, soups, sauces, and savory snacks.

Monosodium glutamate (MSG) dissolves easily in broths and sauces, contributing to a more robust and satisfying taste.
Monosodium glutamate (MSG) is chemically identical to the glutamate naturally present in many foods like tomatoes and cheese.
In culinary terms, Monosodium glutamate (MSG) is recognized for its ability to enhance the overall taste perception of dishes.

Monosodium glutamate (MSG) has a clean, mild aroma that allows it to blend seamlessly with a wide range of ingredients.
Monosodium glutamate (MSG) is a versatile ingredient, finding applications in both home cooking and industrial food production.

Monosodium glutamate (MSG) has a neutral pH, ensuring it does not significantly alter the acidity of recipes.
Its use extends beyond savory dishes, as chefs experiment with incorporating Monosodium glutamate (MSG) into desserts and beverages.

Monosodium glutamate (MSG) is known for its ability to make vegetarian and plant-based dishes more flavorful and satisfying.
The umami taste imparted by Monosodium glutamate (MSG) complements the sweet, sour, salty, and bitter flavors in a dish.
Food manufacturers appreciate Monosodium glutamate (MSG) for its cost-effectiveness in enhancing product palatability.

When used judiciously, Monosodium glutamate (MSG) contributes to a well-balanced and harmonious flavor profile in culinary creations.
Monosodium glutamate (MSG) is often used in conjunction with other seasonings to create a symphony of tastes in a dish.
Monosodium glutamate (MSG) has a negligible caloric content, making it an attractive option for those monitoring calorie intake.

Monosodium glutamate (MSG)'s widespread use reflects its role in enhancing the overall gustatory experience of food.
The culinary world continues to explore innovative ways to incorporate MSG, recognizing its potential to elevate the dining experience.



PROPERTIES


Chemical Formula: C5H8NO4Na
Molecular Weight: 169.11 g/mol
Chemical Structure:
Appearance: White crystalline powder
Odor: Odorless
Taste: Umami (savory)
Solubility in Water: Highly soluble
Melting Point: Decomposes at high temperatures
Density: 1.54 g/cm³
pH: Neutral (around 7 in solution)
Boiling Point: Decomposes before boiling
Stability: Stable under normal conditions
Storage: Store in a cool, dry place away from moisture and heat.
Hygroscopicity: Absorbs moisture from the air.
Water Content: May contain water molecules as it is hygroscopic.
Purity: Typically available in high purity (food-grade) forms.
Solubility in Other Solvents: Generally insoluble in organic solvents.
Crystalline Structure: Forms white, well-defined crystals.
Chemical Stability: Stable under normal processing and cooking conditions.
Flammability: Non-flammable.
Flash Point: Not applicable.
Toxicity: Generally recognized as safe (GRAS) by regulatory bodies when used in accordance with regulations.
Biodegradability: MSG is readily biodegradable.



FIRST AID


Inhalation:

If inhaled and respiratory distress occurs, remove the affected person to fresh air.
If breathing difficulties persist, seek immediate medical attention.


Skin Contact:

If Monosodium glutamate (MSG) comes into contact with the skin, wash the affected area with plenty of water.
Remove contaminated clothing.
If irritation or redness persists, seek medical attention.


Eye Contact:

In case of eye contact, rinse the eyes gently with lukewarm water for at least 15 minutes.
Remove contact lenses if present and easy to do.
Seek medical attention if irritation or redness persists.


Ingestion:

If Monosodium glutamate (MSG) is ingested accidentally and the person experiences adverse reactions such as nausea, vomiting, or allergic symptoms, seek medical attention.
Rinse the mouth with water if there is no risk of aspiration.
Do not induce vomiting unless instructed by medical personnel.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
When handling Monosodium glutamate (MSG), it is advisable to wear appropriate PPE, including gloves and safety glasses, to minimize direct skin contact and eye exposure.

Avoid Inhalation:
Take measures to avoid inhaling Monosodium glutamate (MSG) dust or vapors.
Use in well-ventilated areas or use local exhaust ventilation if handling large quantities.

Prevent Contamination:
Prevent cross-contamination by using clean and dry utensils during handling.
Ensure that containers and equipment are free from residues of incompatible substances.

Hygiene Practices:
Practice good personal hygiene, including handwashing, especially after handling MSG.
Avoid touching the face, eyes, or mouth during handling.

Spill Cleanup:
In case of spills, clean up promptly using appropriate materials.
Avoid creating dust during cleanup.
Dispose of spilled material in accordance with local regulations.

Static Electricity:
Due to its fine powder form, MSG may accumulate static electricity.
Take precautions to ground equipment and containers to minimize the risk of static discharge.


Storage:

Storage Conditions:
Store Monosodium glutamate (MSG) in a cool, dry place away from direct sunlight, heat sources, and moisture.
Maintain storage temperatures within the recommended range.

Containers:
Use containers made of materials compatible with Monosodium glutamate (MSG), such as stainless steel or food-grade plastics.
Ensure containers are tightly sealed to prevent moisture absorption.

Hygroscopicity:
Monosodium glutamate (MSG) is hygroscopic and can absorb moisture from the air, leading to clumping.
Use moisture-resistant packaging or include desiccants in storage containers to maintain product quality.

Separation:
Store MSG away from incompatible substances to prevent cross-contamination.
Keep it separate from strong acids, alkalis, and oxidizing agents.

Labeling:
Clearly label storage containers with the product name, date of receipt, and any relevant safety information.
This ensures proper identification and tracking of the product.

Shelf Life:
Follow the manufacturer's recommendations regarding the shelf life of MSG.
Use a first-in, first-out (FIFO) inventory system to ensure older stock is used before newer batches.

Temperature Control:
Maintain storage temperatures within the recommended range to preserve the quality and stability of MSG.

Security Measures:
Implement security measures to prevent unauthorized access to stored MSG, especially in industrial or commercial settings.
MONOSODIUM LACTATE
Monosodium lactate is a sodium salt of lactic acid, a natural organic acid that is present in many foods, such as yogurt, cheese, sourdough bread, and pickled vegetables.
Monosodium lactate is produced by the neutralization of lactic acid with sodium hydroxide.

CAS Number: 312-85-6
EC Number: 206-104-4



APPLICATIONS


Monosodium Lactate is used as a preservative in food products such as meat, poultry, and seafood.
Monosodium lactate is used in the production of cosmetics as a humectant and moisturizer.

Monosodium Lactate is used as a flavoring agent and pH regulator in the beverage industry.
Monosodium lactate is used as an additive in animal feed to improve their digestion and growth.

Monosodium Lactate is commonly used in the food industry as a preservative and flavoring agent.
Monosodium lactate is also used as a humectant in cosmetic and personal care products.

Monosodium lactate is often added to meat and poultry products to extend their shelf life and improve their texture.
In the pharmaceutical industry, Monosodium Lactate is used as an excipient in oral and topical formulations.
Monosodium lactate can also be used as a chelating agent in metal ion removal processes.

Monosodium lactate is used as a humectant in the cosmetic industry to help retain moisture in the skin.
In the food industry, Monosodium lactate is used as a preservative to extend the shelf life of various products.

Monosodium lactate is used as an antimicrobial agent in meat and poultry products to prevent bacterial growth.
Monosodium lactate is used in the production of sausage casings to improve texture and extend shelf life.

Monosodium lactate is used as a flavor enhancer in various food products, including salad dressings and dips.
Monosodium lactate is used as a processing aid in the dairy industry to prevent spoilage and improve shelf life.

Monosodium lactate is used in the baking industry as a dough conditioner to improve texture and extend shelf life.
Monosodium lactate is used in the pharmaceutical industry as a buffering agent in various medications.
Monosodium lactate is used as a moisturizer in personal care products such as lotions and creams.

Monosodium lactate is used in the production of pet food to improve texture and extend shelf life.
Monosodium lactate is used as a humectant in tobacco products to prevent drying and improve flavor.

Monosodium lactate is used as an ingredient in sports drinks to help replenish electrolytes lost during physical activity.
Monosodium lactate is used as a chelating agent in cleaning products to help remove mineral deposits.

Monosodium lactate is used in the production of biodegradable plastics to improve their properties.
Monosodium lactate is used as a solvent in the manufacturing of various chemicals.
Monosodium lactate is used in the production of animal feed to improve texture and extend shelf life.

Monosodium lactate is used in the production of paper and cardboard to improve strength and durability.
Monosodium lactate is used as a flavoring agent in tobacco products to improve taste.

Monosodium lactate is used in the production of artificial tears to improve viscosity and prolong contact time.
Monosodium lactate is used in the production of leather goods to improve flexibility and softness.

Monosodium lactate is used as a humectant in the pet food industry to prevent drying and improve palatability.
Monosodium lactate is used in the production of adhesives to improve tack and adhesion.

Monosodium lactate is used in the production of detergents to improve cleaning efficacy.
Monosodium lactate is used as a moisturizing agent in hair care products such as shampoos and conditioners.
Monosodium lactate is used as a pH adjuster in various personal care products such as facial cleansers and toners.

Monosodium lactate is used as a preservative in meat, poultry, and seafood products.
Monosodium lactate is commonly used in salad dressings and sauces as a flavor enhancer.

Monosodium lactate is added to baked goods to improve their texture and extend their shelf life.
Monosodium lactate is used as a humectant in cosmetics and personal care products to help retain moisture.
Monosodium lactate is used in the production of tofu and other soy products.

Monosodium lactate is used in the production of cultured dairy products like yogurt and sour cream.
Monosodium lactate is used as a pH regulator and buffering agent in a variety of food and beverage products.

Monosodium lactate is added to pet foods as a flavor enhancer and preservative.
Monosodium lactate is used in the production of pharmaceuticals and medical products.

Monosodium lactate is used in the manufacturing of detergents and cleaning products as a pH regulator.
Monosodium lactate is used in the production of animal feed to improve the nutritional value of the feed.
Monosodium lactate is used as a moisturizer and skin conditioning agent in topical skincare products.

Monosodium lactate is added to sports drinks and other beverages to help replenish electrolytes lost during exercise.
Monosodium lactate is used in the production of synthetic fibers and textiles.

Monosodium lactate is added to canned fruits and vegetables as a preservative.
Monosodium lactate is used in the production of industrial adhesives and sealants.

Monosodium lactate is used as a chelating agent in the production of metal-based products like paint and coatings.
Monosodium lactate is used in the production of leather and other animal hides.
Monosodium lactate is added to dental products like mouthwash and toothpaste as a flavoring agent.

Monosodium lactate is used in the production of biofuels and other renewable energy sources.
Monosodium lactate is added to animal feed to improve digestibility and overall health of livestock.
Monosodium lactate is used in the production of personal lubricants and other intimate care products.

Monosodium lactate is used as a flavoring agent in alcoholic beverages like beer and wine.
Monosodium lactate is used in the production of paper and other pulp-based products.
Monosodium lactate is added to processed foods like canned soups and stews as a preservative and flavor enhancer.

Monosodium lactate is commonly used in the food industry as a preservative for meat and poultry products.
Monosodium lactate is also used as a flavor enhancer in a variety of foods, such as baked goods and processed meats.

In the pharmaceutical industry, monosodium lactate is used as a pH adjuster and buffering agent in various medications.
Monosodium lactate is used in the production of cosmetics and personal care products as a moisturizer and emollient.

Monosodium lactate is used in the production of pet food to help enhance the flavor and extend the shelf life.
Monosodium lactate is used as a plasticizer and lubricant in the manufacturing of plastic and rubber products.

Monosodium lactate is used in the production of biofuels to improve the fermentation process.
Monosodium lactate is used as a water-retaining agent in the production of horticultural and agricultural products.
Monosodium lactate is used in the production of animal feed to improve the digestibility and palatability of the feed.

Monosodium lactate is used as an ingredient in cleaning and sanitizing products due to its antimicrobial properties.
Monosodium lactate is used in the production of detergents and surfactants to improve their effectiveness.

Monosodium lactate is used in the textile industry as a dyeing and printing auxiliary.
Monosodium lactate is used as a humectant and preservative in the tobacco industry.
Monosodium lactate is used as a viscosity regulator in the production of paints and coatings.

Monosodium lactate is used in the production of inks and toners for printers and copiers.
Monosodium lactate is used as a binder and adhesive in the production of ceramics and refractory materials.

Monosodium lactate is used in the paper and pulp industry to improve paper strength and reduce ink smudging.
Monosodium lactate is used as a chelating agent in the production of electroplating solutions.

Monosodium lactate is used as an anti-icing agent for aircrafts and runways.
Monosodium lactate is used as a descaling agent in the cleaning of industrial equipment.

Monosodium lactate is used in the production of leather and leather products to improve softness and durability.
Monosodium lactate is used as a component in the production of some types of adhesives and sealants.
Monosodium lactate is used in the production of rubber products to improve their elasticity and strength.

Monosodium lactate is used in the production of printing plates for the printing industry.
Monosodium lactate is used in the production of some types of batteries and electronic devices.


Monosodium lactate has various applications in different fields, including:

In the food industry, as a food preservative and flavoring agent.
As a pH adjuster and buffering agent in the cosmetic industry.
In the production of pet food, as a flavoring agent and source of energy.
In the production of animal feed, as a source of energy and growth promoter.
In the pharmaceutical industry, as an excipient and solubilizer for active ingredients.
As a moisturizing agent in personal care products, such as lotions and creams.
As a humectant in the cosmetic and personal care industry to help retain moisture.
In the production of detergents and cleaning products, as a chelating agent and pH adjuster.
In the production of textiles, as a dyeing auxiliary and color fixing agent.
In the production of leather, as a tanning agent and pH adjuster.
In the production of paper, as a sizing agent and wet strength agent.
As a buffering agent in the production of antiseptic solutions and disinfectants.
In the fermentation industry, as a nutrient source for bacterial cultures.
As a source of energy and electrolytes in sports drinks and nutritional supplements.
In the production of polymer resins, as a cross-linking agent.
As a de-icing agent for roads and sidewalks.
In the production of adhesives and sealants, as a plasticizer and rheology modifier.
As a coagulant in the production of latex and rubber products.
As a preservative in the horticulture industry to extend the shelf life of fresh produce.
In the production of water treatment chemicals, as a corrosion inhibitor and stabilizer.
In the production of oil drilling fluids, as a pH adjuster and clay stabilizer.
In the production of metalworking fluids, as a pH adjuster and lubricant.
As a feedstock for the production of other chemicals, such as propylene glycol.
As a flavor enhancer and pH adjuster in the production of wine and beer.
In the production of biodiesel, as a catalyst and emulsifier.



DESCRIPTION


Monosodium lactate is a sodium salt of lactic acid, a natural organic acid that is present in many foods, such as yogurt, cheese, sourdough bread, and pickled vegetables.
Monosodium lactate is produced by the neutralization of lactic acid with sodium hydroxide.

Monosodium lactate is a white or colorless crystalline powder or a clear, colorless liquid that is highly soluble in water.
Monosodium lactate has a slightly salty and sour taste and is used as a food additive to enhance flavor, preserve freshness, and extend shelf life.

Monosodium lactate also has several non-food applications, such as in cosmetics, personal care products, and pharmaceuticals.
Monosodium lactate is generally recognized as safe (GRAS) by the United States Food and Drug Administration (FDA) and is approved for use in food products in many countries around the world.

Monosodium lactate is the sodium salt of lactic acid, which is a natural organic acid.
Monosodium lactate has a chemical formula of C3H5NaO3 and a molecular weight of 112.06 g/mol.

Monosodium lactate is a white to off-white powder or liquid with a slightly sweet taste.
Monosodium lactate is soluble in water and slightly soluble in alcohol.
Monosodium lactate has an odorless to slightly sweet odor.

Monosodium lactate is a food additive used as a preservative, flavoring agent, and acidity regulator.
Monosodium lactate is commonly used in meat and poultry products to extend shelf life and improve flavor and texture.

Monosodium lactate is also used in baked goods, dairy products, and beverages to enhance taste and prevent spoilage.
Monosodium lactate is also used in cosmetics and personal care products as a humectant and moisturizer.

Monosodium lactate helps to attract and retain moisture in the skin, hair, and nails.
Monosodium lactate is used in the medical industry as a component in intravenous (IV) fluids and dialysis solutions.
Monosodium lactate is also used in the production of biodegradable plastics.

Monosodium lactate is a safer alternative to conventional plastics as it breaks down into non-toxic compounds.
Monosodium lactate has antimicrobial properties and is effective against a wide range of bacteria, fungi, and viruses.

Monosodium lactate has been shown to have antioxidant and anti-inflammatory properties, which may have potential health benefits.
Monosodium lactate can help to reduce the risk of chronic diseases such as cancer and heart disease.

Monosodium lactate has low toxicity and is considered safe for consumption by regulatory agencies.
Monosodium lactate is also used in the textile industry as a dyeing and finishing agent.

Monosodium lactate improves color fastness and enhances the softness and durability of fabrics.
Monosodium lactate is biodegradable and environmentally friendly.

Monosodium lactate does not contribute to pollution or harm to wildlife.
Monosodium lactate has a wide range of applications in the food, cosmetic, medical, and industrial fields.
Monosodium lactate is a versatile chemical with many beneficial properties.

Monosodium lactate is affordable and readily available in the market.
Monosodium lactate is an excellent choice for manufacturers looking for a safe, effective, and sustainable ingredient for their products.



PROPERTIES


Chemical formula: C3H5NaO3
Molecular weight: 112.06 g/mol
Appearance: Clear, colorless to slightly yellowish liquid or powder
Odor: Odorless or slight characteristic odor
Solubility: Soluble in water, slightly soluble in ethanol, insoluble in ether and chloroform
Density: 1.33 g/cm3 (20 °C)
Melting point: 72-73 °C
Boiling point: 121-122 °C (10 mmHg)
pH value: 6.0-7.5 (1% solution in water)
Viscosity: 4-5 mPa.s (20 °C)
Refractive index: 1.421-1.423 (20 °C)
Heat of combustion: -3.29 MJ/kg
Flash point: 114 °C (238 °F) (closed cup)
Autoignition temperature: 400 °C (752 °F)
Flammability: Not flammable
Explosive properties: Not explosive
Oxidizing properties: Not oxidizing
Hygroscopicity: Hygroscopic
Stability: Stable under normal conditions of use and storage
Hazardous decomposition products: Carbon dioxide, carbon monoxide, sodium oxide, lactate
Vapor pressure: 3.4 Pa (20 °C)
Octanol/water partition coefficient (log Kow): -1.73
Water solubility: 800 g/L (20 °C)
Purity: ≥98% (liquid), ≥99% (powder)



FIRST AID


Here are some first aid measures for Monosodium lactate:


Eye Contact:

Rinse the affected eye(s) immediately with plenty of water.
Seek medical attention if irritation persists.


Skin Contact:

Wash the affected area thoroughly with soap and water.
Remove contaminated clothing and shoes.
If skin irritation occurs, seek medical attention.


Inhalation:

Move the affected person to fresh air immediately.
If breathing becomes difficult, seek medical attention.


Ingestion:

Rinse mouth thoroughly with water.
Do not induce vomiting.
Seek medical attention immediately.


Note: It is important to always refer to the safety data sheet (SDS) and follow the recommended first aid measures provided by the manufacturer or supplier.



HANDLING AND STORAGE


Sure, here are some handling and storage information for Monosodium lactate:


Handling:

Wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat.
Avoid contact with eyes, skin, and clothing.
Wash thoroughly after handling.
Store in a cool, dry, and well-ventilated area.
Do not breathe dust or vapor.


Storage:

Store in a tightly closed container.
Keep away from incompatible substances such as strong oxidizing agents.
Keep away from heat and direct sunlight.
Store in a cool, dry, and well-ventilated area.
Store in a designated area for hazardous materials.
Keep out of reach of children and unauthorized personnel.



SYNONYMS


Sodium lactate monohydrate
Sodium 2-hydroxypropanoate
Lactic acid sodium salt
E325
Lactic acid monosodium salt
Monosodium 2-hydroxypropanoate
Sodium alpha-hydroxypropionate
Sodium (S)-lactate
Lactate sodium
Neutral sodium lactate
Sodium lactate solution
Sodium 2-hydroxypropionate monohydrate
Lactic acid, sodium salt, monohydrate
Sodium lactate monohydrate solution
2-Hydroxypropanoic acid sodium salt
Monosodium (S)-2-hydroxypropanoate
Sodium lactate monohydrate, USP
Sodium L-lactate
Neutralizing agent sodium lactate
Sodium lactate hydrate
2-Hydroxypropanoic acid, monosodium salt
Sodium lactate monohydrate, FCC
Sodium L-lactate hydrate
Neutralizing sodium salt of lactic acid
Lactic acid sodium salt monohydrate
Sodium 2-hydroxypropanoate
Sodium lactate monohydrate
Lactic acid sodium salt
Monosodium 2-hydroxypropanoate
Sodium alpha-hydroxypropionate
Monosodium DL-lactate
E325
Nalactone
Monosodium DL-2-hydroxypropanoate
2-hydroxypropanoic acid, sodium salt
Lactic acid, monosodium salt, monohydrate
Sodi lactas monohydratus
Sodi lactas
Lactato monosodico
Monosodio dell'acido lattico
Mononatriumlactat
Mononatriumlaktat-monohydrat
Natrii lactas monohydricus
Natriumlactat, monohydrat
Sodium DL-lactate monohydrate
Sodium lactate hydrate
Sodium lactate monohydrate (JP17)
Sodium, lactate monohydrate (8CI)
Lactic acid, sodium salt, monohydrate
UNII-YP7309Y3ZM
MONOSODIUM N-LAUROYL-L-GLUTAMATE
DESCRIPTION:
Monosodium n-lauroyl-l-glutamate is an antiasthmatic.
Monosodium n-lauroyl-l-glutamate is a Sodium salt of the lauric acid amide of glutamic acid
Sodium lauroyl glutamate uses and applications include: Antistat, surfactant, emulsifier, detergent, emollient for cosmetics; bacteriostat

CAS Number: 29923-31-7
EC Number: 249-958-3
Molecular Weight: 351.41
Empirical Formula (Hill Notation): C17H30NNaO5

SYNTHESIS METHOD DETAILS OF MONOSODIUM N-LAUROYL-L-GLUTAMATE:
Design of the Synthesis Pathway:
The synthesis pathway for N-Lauroyl-L-glutamic acid involves the amidation of L-glutamic acid with lauroyl chloride in the presence of a base.

Starting Materials:
L-glutamic acid, Lauroyl chloride, Base (e.g. triethylamine or sodium hydroxide), Solvent (e.g. dichloromethane or chloroform)

Reaction:
Dissolve L-glutamic acid in the solvent
Add the base to the solution
Add lauroyl chloride dropwise to the solution while stirring
Heat the solution to reflux for several hours
Allow the solution to cool and filter the precipitate
Wash the precipitate with the solvent
Dry the product under vacuum








CHEMICAL AND PHYSICAL PROPERTIES OF MONOSODIUM N-LAUROYL-L-GLUTAMATE:
Boiling Point543.6ºC at 760 mmHg
Appearance White or of- white powder or crystlline power,odorless
Solubility Very soluble in N,N-Dimethylformamide,Soluble in methanol,Sparingly soluble inglacial acetic acid, Very slightly soluble inchloroform, Practically insoluble in water.
PSA: 106.53000
XLogP3: 2.39770
Boiling Point: 543.6ºC at 760 mmHg
Flash Point: 282.6ºC
Molecular Formula C17H30NO5.Na
Molar Mass 351.42
Density 1.277[at 20℃]
Water Solubility 1.11g/L at 20℃
Vapor Presure 5Pa at 20℃
pKa 3.78[at 20 ℃]
Storage Condition Room Temperature
Shelf Life >3 years if stored properly
Solubility Soluble in DMSO
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Boiling Point: 543.6oC at 760 mmHg
Flash Point: 282.6oC
Density: 1.277[at 20℃]
Vapor Pressure: 5Pa at 20℃
PKA: 3.78[at 20 ℃]
Water Solubility: 1.11g/L at 20℃
CAS DataBase Reference: Sodium lauroyl glutamate(CAS DataBase Reference)
NIST Chemistry Reference: Sodium lauroyl glutamate(29923-31-7)
EPA Substance Registry System: Sodium lauroyl glutamate(29923-31-7)

SAFETY INFORMATION ABOUT MONOSODIUM N-LAUROYL-L-GLUTAMATE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product








SYNONYMS OF MONOSODIUM N-LAUROYL-L-GLUTAMATE:
N-(1-Oxododecyl)-L-glutamic acid monosodium salt
N-Lauroyl-L-glutamic acid monosodium salt
Sodium N-dodecanoylglutamate
Sodium lauroyl glutamate
acylglutamate ls-11
Sodium lauroylglutamate
SODIUM LAUROYL GLUTAMATE
N-dodecanoyl-L-glutamic acid
SODIUM-N-LAUROYL-L-GLUTAMATE
monosodium n-lauroyl-l-glutamate
(N-(1-OXODODECYL)1-L-GLUTAMIC ACID
n-lauroyl-l-glutamic acid monosodium salt
sodium hydrogen N-(1-oxododecyl)-L-glutamate
L-Glutamic acid,N-(1-oxo-dodecyl)-,sodium salt
n-(1-oxododecyl)-l-glutamic aci monosodium salt
L-Glutamic acid, N-(1-oxo-dodecyl)-, sodium salt
sodium (2S)-4-carboxy-2-(dodecanoylamino)butanoate
L-Glutamic acid, N-(1-oxododecyl)-, monosodium salt
n-lauroyl-glutamic aci l-glutamic aci monosodium salt
sodium 1-[(5-oxidanidyl-5-oxidanylidenenorvalyl)oxy]-1-oxododecane




MONOSODIUM PHOSPATE DIHYDRATE
Monosodium phosphate SODIUM DIHYDROGEN PHOSPHATE Sodium dihydrogenorthophosphate Sodium phosphate monobasic Sodium acid phosphate Sodium phosphate, monobasic Monosodium dihydrogen orthophosphate sodium dihydrogenphosphate Acid sodium phosphate Monosodium monophosphate Sodium phosphate monobasic anhydrous Sodium primary phosphate Monosodium orthophosphate Sodium dihydrogen orthophosphate Monobasic sodium phosphate Monosorb XP-4 Phosphoric acid, sodium salt Monosodium dihydrogen phosphate Monosodium phosphate, anhydrous CAS 7558-80-7
MONOSODIUM PHOSPHATE
MONOSODIUM PHOSPHATE (2 HYDRATE) cas no: 13472-35-0
MONOSODIUM PHOSPHATE
Monosodium phosphate, also known as monobasic sodium phosphate and sodium dihydrogen phosphate, is an inorganic compound of sodium with a dihydrogen phosphate (H2PO4−) anion.
One of many sodium phosphates, Monosodium phosphate is a common industrial chemical.
The salt exists in an anhydrous form, as well as mono- and dihydrates.

CAS: 7558-80-7
MF: H3O4P.Na
MW: 119.977
EINECS: 231-449-2

Monosodium phosphate is a sodium phosphate.
Monosodium phosphate is a food grade white powder that stabilizes and corrects the pH of several dairy products.
Monosodium phosphate also acts for pH adjustment and as buffer for tooth paste.
Monosodium phosphate is a white powder, which complies with the specifications of the current Food Chemicals Codex for Sodium Phosphate, Monobasic.
Monosodium phosphate is used as an acidulant, buffering agent, emulsifying agent, and protein modifier.

Monosodium phosphate can be used as a gelling aid by use of its acidulation properties.
Monosodium phosphate also accelerates gelation in custard pudding and no-bake cheesecake mixes.
The acidifying effects of Monosodium phosphate can be used to bring tartness to non-cola beverages.
Monosodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine.
Monosodium phosphate usually results in a bowel movement after 30 minutes to 6 hours.
Monosodium Phosphate is used as a buffering agent for a wide array of products.
Monosodium phosphate is also used to control pH in water treatment applications.

Monosodium phosphate Chemical Properties
Melting point: <0°C
Boiling point: 100°C
Density: 1.40 g/mL at 20 °C
Vapor pressure: 0Pa at 20℃
Storage temp.: room temp
Solubility H2O: 5 M, clear, colorless
Form: powder
Color: White
PH: 4.0 - 4.5 (25℃, 50g/L in water)
pka: (1) 2.15, (2) 6.82, (3) 12.38 (at 25℃)
Odor: at 100.00?%. odorless
Water Solubility: Soluble in water. Insoluble in alcohol,ether and chloroform.
λmax: λ: 260 nm Amax: ≤0.025
λ: 280 nm Amax: ≤0.02
Sensitive: Hygroscopic
Merck: 14,8660
BRN: 3903772
Stability:: Stable. Incompatible with heavy metals, strong acids.
InChIKey: AJPJDKMHJJGVTQ-UHFFFAOYSA-M
LogP: -2.148 (est)
CAS DataBase Reference: 7558-80-7(CAS DataBase Reference)
EPA Substance Registry System: Monosodium phosphate (7558-80-7)

The USP 32 states that Monosodium phosphate contains one or two molecules of water of hydration or is anhydrous.
The hydrated forms of Monosodium phosphate occur as odorless, colorless or white, slightly deliquescent crystals.
The anhydrous form occurs as a white crystalline powder or granules.
White, slightly deliquescent crystals or granules.

Physical properties
Anhydrous salt: white crystalline powder; slightly hygroscopic; forms sodium acid pyrophosphate, Na2H2P2O7 on heating above 225°C and sodium metaphosphate (NaPO3)n at about 350 to 400°C; very soluble in water, aqueous solution acidic.
Monohydrate: white orthorhombic crystals or granules; density 2.04 g/cm3; loses its water of crystallization at 100°C; very soluble in water, pH of 1% solution 4.5; insoluble in alcohol.
Dihydrate: large transparent crystals; orthorhombic bisphenoidal structure; density 1.915 g/cm3; decomposes at 60°C; very soluble in water; insoluble in alcohol.

Uses
Monosodium phosphate is used as sequestrant, emulsifier, mordant in dyeing, reagent and buffer in foods and analytical chemistry.
Monosodium phosphate was applied as a fireproofing agent and for weighting silk in tanning.
Monosodium phosphate is employed in manufacturing of enamels, ceramics, detergents, boiler compounds, in soldering and brazing instead of borax.

Monosodium phosphate has been used:
as a reagent for virus transfection and fiber implantation in mouse
in phosphate buffer for immunocytochemistry and to detect individual catalase activity by PAGE (polyacrylamide gel electrophoresis)
as a buffer for cycling assay
in automated DNA extraction method
as a chemical in artificial cerebro-spinal fluid (aCSF) solution for the preparation of brainstem-spinal cord from rats

Phosphates are often used in foods and in water treatment.
The pH of such formulations is generally adjusted by mixtures of various sodium phosphates, such as this salt.
The sodium chloride equivalent value, or E-Value, is 0.49.
Monosodium phosphate is soluble in 4.5 parts water.

Pharmaceutical Applications
Monosodium phosphate is used in a wide variety of pharmaceutical formulations as a buffering agent and as a sequestering agent.
Therapeutically, Monosodium phosphate is used as a mild saline laxative and in the treatment of hypophosphatemia.
Monosodium phosphate is also used in food products, for example, in baking powders, and as a dry acidulant and sequestrant.

Food additive
Monosodium phosphate is added in animal feed, toothpaste, and evaporated milk.
Monosodium phosphate is used as a thickening agent and emulsifier.

Detection of magnesium
Monosodium phosphate is used to detect the presence of magnesium ions in salts.
Formation of a white precipitate on the addition of ammonium chloride, ammonium hydroxide and Monosodium phosphate to an aqueous or dilute HCl solution of the salt indicates presence of magnesium ions.

Production and reactions
The salt is obtained by partial neutralization of phosphoric acid.
The pKa of monosodium phosphate is 6.8-7.2 (depending on the physicochemical characteristics during pKa determination).

Heating this salt above 169 °C gives the corresponding sodium acid pyrophosphate:

2 NaH2PO4 → Na2H2P2O7 + H2O
When heated at 550 °C, anhydrous trisodium trimetaphosphate results:

3NaH2PO4 → Na3P3O9 + 3 H2O

Synonyms
Monosodium phosphate
7558-80-7
SODIUM DIHYDROGEN PHOSPHATE
Sodium phosphate monobasic
Sodium dihydrogenorthophosphate
Sodium acid phosphate
Sodium phosphate, monobasic
Sodium primary phosphate
Monosodium dihydrogen orthophosphate
Monosodium monophosphate
Monosodium phosphate, anhydrous
Sodium phosphate monobasic anhydrous
Monobasic sodium phosphate
Acid sodium phosphate
Monosodium orthophosphate
sodium dihydrogenphosphate
Sodium dihydrogen orthophosphate
Monosorb XP-4
Monosodium dihydrogen phosphate
Sodium dihydrogen phosphate, anhydrous
Primary sodium phosphate
Phosphoric acid, monosodium salt
Sodium phosphate (Na(H2PO4))
sodium;dihydrogen phosphate
Sodium biphosphate anhydrous
Monosodium hydrogen phosphate
Sodium biphosphate, anhydrous
Sodium phosphate (NaH2PO4)
Sodium orthophosphate, primary
Sodium dihydrogen monophosphate
Sodium orthophosphate monobasic
HSDB 738
NaH2PO4
EINECS 231-449-2
Sodium phosphate,monobasic
UNII-KH7I04HPUU
KH7I04HPUU
89140-32-9
Sodium dihydrogen phosphate (1:2:1)
Sodium monobasic phosphate (NaH2PO4)
Sodium dihydrogen phosphate (NaH2PO4)
SODIUM PHOSPHATE, MONOBASIC ANHYDROUS
INS NO.339(I)
CHEBI:37585
SODIUM PHOSPHATE, MONOBASIC, ANHYDROUS
Monosodium dihydrogen monophosphate
INS-339(I)
MFCD00003527
Sodium phosphate monobasic (anhydrate)
Sodium phosphate monobasic (anhydrous)
E-339(I)
phosphoric acid, monosodium salt, anhydrous
EC 231-449-2
MSP
MFCD00146206
Clicolon
Sodiumdihydrogenphosphate-16O4
Sodium phosphate monobasic, anhydrous
sodiumdihydrogenphosphate
sodium dihydrogenphoshate
sodium dihydrogenphospate
sodium dihydrogenphosphat
sodiumdihydrogen phosphate
natriumdihydrogen-phosphate
H2O4P.Na
H3O4P.Na
sodium dihydrogen-phosphate
sodium phosphate mono-basic
UNII-SE337SVY37
H3-O4-P.Na
INKP-100
SE337SVY37
DTXSID7035222
AJPJDKMHJJGVTQ-UHFFFAOYSA-M
Sodium phosphate, monobasic (USP)
Anhydrous monobasic sodium phosphate
Phosphoric acid sodium salt (1:1)
Sodium dihydrogenphosphate (granular)
Phosphoric acid, sodium salt (1:?)
Phosphoric acid, sodium salt (1:1)
AKOS024433265
AT32901
DB09449
LS-2421
SODIUM PHOSPHATE MONOBASIC [HSDB]
Sodium phosphate monobasic, AR, >=98%
Sodium phosphate monobasic, LR, >=97%
SODIUM PHOSPHATE, MONOBASIC [MI]
E339
SODIUM PHOSPHATE,MONOBASIC [VANDF]
FT-0698935
Sodium phosphate monobasic, for HPLC, 99%
D04400
Sodium phosphate monobasic, BioXtra, >=99.0%
Q415877
Sodium phosphate monobasic, USP, 98.0-103.0%
SODIUM PHOSPHATE, MONOBASIC, ANHYDROUS [II]
2-Methyl-3-(pyridin-4-ylmethyl)quinazolin-4(3H)-one
Sodium phosphate monobasic, ReagentPlus(R), >=99.0%
SODIUM PHOSPHATE MONOBASIC (ANHYDROUS) [WHO-DD]
Sodium phosphate monobasic, 99.999% trace metals basis
Sodium phosphate monobasic, Vetec(TM) reagent grade, 99%
SODIUM PHOSPHATE, MONOBASIC ANHYDROUS [ORANGE BOOK]
SODIUM PHOSPHATE, MONOBASIC, ANHYDROUS [ORANGE BOOK]
Sodium phosphate monobasic, SAJ first grade, 98.0-101.0%
Sodium phosphate monobasic, SAJ special grade, 99.0-101.0%
Sodium phosphate monobasic, purum p.a., anhydrous, >=99.0% (T)
Sodium phosphate monobasic, meets USP testing specifications, anhydrous
Sodium phosphate monobasic, anhydrous, free-flowing, Redi-Dri(TM), >=99.0%
Sodium phosphate monobasic, BioReagent, for molecular biology, anhydrous, >=98%
Sodium phosphate monobasic, Biotechnology Performance Certified, Cell Culture Tested
Sodium phosphate monobasic Molecular Biology Grade, suitable for cell culture, insect cell culture, and plant cell culture
Sodium phosphate monobasic, BioPerformance Certified, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, >=99.0% (titration)
MONOSODIUM PHOSPHATE DIHYDRATE
Monosodium Phosphate Dihydrate is also known as monosodium phosphate or sodium dihydrogen phosphate dihydrate
Monosodium Phosphate Dihydrate is a white, crystalline powder
Monosodium Phosphate Dihydrate is highly soluble in water.


CAS NUMBER: 13472-35-0

EC NUMBER: 603-853-2

MOLECULAR FORMULA: H6NaO6P

MOLECULAR WEIGHT: 156.01 g/mol

IUPAC NAME: sodium;dihydrogen phosphate;dihydrate



The dihydrate form indicates that it contains two water molecules per molecule of sodium phosphate monobasic.
Monosodium Phosphate Dihydrate is a reagent with very high buffering capacity

Monosodium Phosphate Dihydrate widely used in molecular biology, biochemistry and chromatography.
Monosodium Phosphate Dihydrate is highly hygroscopic and water soluble.

Monosodium Phosphate Dihydrate is used in the preparation of biological buffers.
Monosodium Phosphate Dihydrate is used in many applications including the purification of antibodies.

Monosodium Phosphate Dihydrate is commonly used in various applications, including as a food additive, pH buffer, and a laboratory reagent.
In the food industry, Monosodium Phosphate Dihydrate is utilized as a sequestrant, emulsifier, and acidulant, contributing to the texture, taste, and preservation of food products.

As a pH buffer, Monosodium Phosphate Dihydrate helps maintain a stable pH level in various solutions, making it valuable in laboratory and industrial settings.
In addition to Monosodium Phosphate Dihydrate's applications in the food and laboratory sectors, sodium phosphate monobasic dihydrate is also utilized in the pharmaceutical industry.
Monosodium Phosphate Dihydrate can be found in some medications as an excipient, aiding in the formulation and stabilization of drugs.

Monosodium Phosphate Dihydrate is important to handle sodium phosphate monobasic dihydrate with care and follow proper safety precautions, as it may irritate the skin, eyes, and respiratory system.
Monosodium Phosphate Dihydrate is advised to wear appropriate protective equipment when working with this compound.

Overall, Monosodium Phosphate Dihydrate is a versatile chemical compound that finds utility in several industries
Monosodium Phosphate Dihydrate is playing roles in food production, pH regulation, and pharmaceutical formulation.

Monosodium Phosphate Dihydrate is also known as monobasic sodium phosphate and sodium dihydrogen phosphate
Monosodium Phosphate Dihydrate is an inorganic compound of sodium with a dihydrogen phosphate (H2PO4−) anion.

One of many sodium phosphates, Monosodium Phosphate Dihydrate is a common industrial chemical.
The salt exists in an anhydrous form, as well as mono- and dihydrates.

Production and Reactions:
The salt is obtained by partial neutralization of phosphoric acid.
The pKa of monosodium phosphate is 6.8-7.2 (depending on the physicochemical characteristics during pKa determination).

Heating this salt above 169 °C gives the corresponding sodium acid pyrophosphate:
2 NaH2PO4 → Na2H2P2O7 + H2O

When heated at 550 °C, anhydrous trisodium trimetaphosphate results:
3NaH2PO4 → Na3P3O9 + 3 H2O

USES:
Phosphates are often used in foods and in water treatment.
The pH of such formulations is generally adjusted by mixtures of various sodium phosphates, such as this salt.
The sodium chloride equivalent value, or E-Value, is 0.49. It is soluble in 4.5 parts water.

Food Additive:
Monosodium Phosphate Dihydrate is added in animal feed, toothpaste, and evaporated milk.
Monosodium Phosphate Dihydrate is used as a thickening agent and emulsifier.

Detection of Magnesium:
Monosodium Phosphate Dihydrate is used to detect the presence of magnesium ions in salts.
Formation of a white precipitate on the addition of ammonium chloride, ammonium hydroxide and monosodium phosphate to an aqueous or dilute HCl solution of the salt indicates presence of magnesium ions.

Monosodium Phosphate Dihydrate is a saline laxative that is thought to work by increasing fluid in the small intestine.
Monosodium Phosphate Dihydrate is soluble in water
Monosodium Phosphate Dihydrate is insoluble in alcohol,ether and chloroform.

Monosodium Phosphate Dihydrate is an acidulant, buffer, and sequestrant
Monosodium Phosphate Dihydrate is mildly acid, with a ph of 4.5

Monosodium Phosphate Dihydrate very soluble in water, with a solubility of 87 g/100 ml of water at 25°c.
Monosodium Phosphate Dihydrate is used as an acidulant in effervescent powders and laxatives.

Monosodium Phosphate Dihydrate is also used in soft drink dry-mix formulations, in cheese, and in carbonated beverages.
Monosodium Phosphate Dihydrate is also termed monosodium dihydrogen orthophosphate; sodium phosphate, monobasic; sodium biphosphate; sodium acid phos- phate; and monosodium monophosphate.


PHYSICAL PROPERTIES:

-Molecular Weight: 156.01 g/mol

-Exact Mass: 155.97996919 g/mol

-Monoisotopic Mass: 155.97996919 g/mol

-Topological Polar Surface Area: 82.6Ų

-Physical Description: Colorless to white hygroscopic solid

-Density: 1.40g/mLat 20°C

-Melting Point: <0°C

-Boling Point: 100°C

-Vapor Presure: 0Pa

-Water Solubility: Soluble in water


Monosodium Phosphate Dihydrate is a common pharmaceutical chemical having a white crystal-like appearance.
One of many sodium phosphates, Monosodium Phosphate Dihydrate is an inorganic sodium compound with a dihydrogen phosphate anion (H_2 PO_4^-).

Monosodium Phosphate Dihydrate's IUPAC name is Sodium dihydrogen phosphate
Generally, the salt exists in three forms: anhydrous, monohydrate and dihydrate.


CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 4

-Hydrogen Bond Acceptor Count: 6

-Rotatable Bond Count: 0

-Heavy Atom Count: 8

-Formal Charge: 0

-Complexity: 61.9

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 4

-Compound Is Canonicalized: Yes

-Chemical Classes: Metals -> Phosphates, Metallic Salts


Monosodium Phosphate Dihydrate is used as a food additive in animal feed, evaporated milk, and toothpaste.
Monosodium Phosphate Dihydrate is also used as an emulsifier as well as a thickening agent.

The presence of magnesium ion can be detected with the help of this salt.
The monohydrate form of Monosodium Phosphate Dihydrate is a reagent with a large buffering capacity.
This inorganic sodium compound finds wide application in the field of biochemistry, molecular biology, and chromatography.

Monosodium Phosphate Dihydrate has various alternative names such as:
-Sodium dihydrogen phosphate monohydrate

-Sodium phosphate monobasic monohydrate

-Sodium dihydrogen phosphate hydrate

-Phosphoric acid, monosodium salt, monohydrate


Monosodium Phosphate Dihydrate is highly hygroscopic
Monosodium Phosphate Dihydrate is water-soluble compound

Monosodium Phosphate Dihydrate is a reagent with a large buffering capacity.
Monosodium Phosphate Dihydrate is used in the purification of antibodies.

Monosodium Phosphate Dihydrate is also used in manufacture of leather and textile products.
Monosodium Phosphate Dihydrate has a crystalline form

Monosodium Phosphate Dihydrate is a reagent with very high buffering capacity
Monosodium Phosphate Dihydrate widely used in molecular biology, biochemistry and chromatography.

Monosodium Phosphate Dihydrate is used in the preparation of biological buffers.
Monosodium Phosphate Dihydrate is used in many applications including the purification of antibodies.

Monosodium Phosphate Dihydrate can be found in some medications as an excipient, aiding in the formulation and stabilization of drugs.
Monosodium Phosphate Dihydrate is an inorganic compound of sodium with a dihydrogen phosphate (H2PO4−) anion.

Monosodium Phosphate Dihydrate is added in animal feed, toothpaste, and evaporated milk.
Monosodium Phosphate Dihydrate is used as a thickening agent and emulsifier.
Monosodium Phosphate Dihydrate is insoluble in alcohol

Monosodium Phosphate Dihydrate is used as an acidulant
Monosodium Phosphate Dihydrate is also used in soft drink dry-mix formulations in carbonated beverages.


SYNONYMS:

13472-35-0
Sodium dihydrogen phosphate dihydrate
Sodium phosphate monobasic dihydrate
Monosodium phosphate dihydrate
Phosphoric acid, monosodium salt, dihydrate
Sodium phosphate, monobasic, dihydrate
Sodium phosphate dihydrate
sodium dihydrogenphosphate dihydrate
Monosodium dihydrogen phosphate dihydrate
sodium;dihydrogen phosphate;dihydrate
Sodium phosphate (NaH2PO4) dihydrate
UNII-5QWK665956
5QWK665956
MFCD00149209
H2O4P.Na.2H2O
mono-sodium phosphate dihydrate
Sodiumphosphatemonobasicdihydrate
dihydratemonobasicsodium phosphate
H2-O4-P.Na.2H2-O
DTXSID90158903
sodium dihydrogenphosphate-dihydrate
sodium dihydrogen-phosphate dihydrate
sodium dihydrogenphosphate di-hydrate
AKOS028109516
Phosphoric Acid Monosodium Salt Dihydrate
MONOBASIC SODIUM PHOSPHATE DIHYDRATE
LS-145530
FT-0645121
MONOBASIC SODIUM PHOSPHATE, DIHYDRATE
SODIUM PHOSPHATE MONOBASIC (DIHYDRATE)
MONOSODIUM DIHYDROGEN PHOSPHATE, DIHYDRATE
SODIUM PHOSPHATE, MONOBASIC, DIHYDRATE
SODIUM PHOSPHATE, MONOBASIC, DIHYDRATE
Q27262757
SODIUM PHOSPHATE MONOBASIC (DIHYDRATE)
SODIUM DIHYDROGEN PHOSPHATE DIHYDRATE
Sodium phosphate monobasic dihydrate
MSP
monosorbxp-4
acidsodiumphosphate
Monosodium Phosphate
Mono Sodium Phosphate
SODIUMDIHYDROPHOSPHATE
MONOSODIUMPHOSPHATE(BULK
SODIUMMONOBASICPHOSPHATE
NATRIUMDIHYDROGENPHOSPHATE
Sodium phosphate monobasic
Sodium phosphate, monobasic
monosodiumhydrogenphosphate
Sodium dihydrogen phosphate
phosphatemonobasiquedesodium
MONOSODIUM PHOSPHATE ANHYDROUS
Monosodium Phosphate anhydride
Monosodium Phosphate Dihydrate
Sodium Dihydrogen Monophosphate
sodium dihydrogenorthophosphate
SODIUM DIHYDROGEN PHOSPHATE-16O4
SODIUMSALTSOFORTHOPHOSPHORICACID
monosodiumdihydrogenorthophosphate
monosodiumphosphate(sodiumdihydrogen
sodium dihydrogen phosphate anhydrous
MONOBASICSODIUMPHOSPHATE,ANHYDROUS,USP
Sodium dihydrogen phosphate, anhydrous
monosodiumphosphate(sodiumdihydrogenphosphate)
MONOSODIUMPHOSPHATE 
Glutamic acid, monosodium salt; MSG; L-Glutamic Acid Monosodium Salt; Sodium L-Glutamate, Mono; L-(+)sodium glutamate; Glutamate monosodium salt; monosodium-L-glutamate; sodium-L-glutamate; L-Glutamic acid, monosodium salt, monohydrate; Glutammato Monosodico (Italian); Natriumglutaminat (German); Hidrogenoglutamato de sodio (Spanish); Hydrogénoglutamate de sodium (French) CAS NO: 142-47-2 (Anhydrous) 6106-04-3 (Monohydrate)
MORPHOLINE
SYNONYMS Tetrahydro-2H-1,4-oxazine; Diethylene oximide; Tetrahydro-1,4-oxazine; Diethylenimide oxide; Tetrahydro-4H-1-4-oxazine; Diethylene imidoxide; 1-Oxa-4-azacyclohexane; Tetrahydro-p-isoxazine; Tetrahydro-p-oxazine; CAS NO. 110-91-8
MORPHOLINE
Morpholine, also known as 1, 4-oxazepine and diethylenimine oxide, is a kind of colorless alkaline oily liquid.
Morpholine smells of ammonia and has hygroscopicity.
Morpholine could evaporate with water vapor and miscible with water.

CAS: 110-91-8
MF: C4H9NO
MW: 87.12
EINECS: 203-815-1

Morpholine is an organic chemical compound having the chemical formula O(CH2CH2)2NH.
This heterocycle features both amine and ether functional groups.
Because of the amine, morpholine is a base; Morpholine's conjugate acid is called morpholinium.
For example, treating morpholine with hydrochloric acid makes the salt morpholinium chloride.
Morpholine is a colorless liquid with a weak, ammonia- or fish-like odor.
The naming of morpholine is attributed to Ludwig Knorr, who incorrectly believed it to be part of the structure of morphine.
Morpholine appears as a colorless liquid with a fishlike odor.
Flash point 100 °F.
Corrosive to tissue.
Less dense than water and soluble in water.
Vapors heavier than air.
Used to make other chemicals, as a corrosion inhibitor, and in detergents.

Morpholine is an organic heteromonocyclic compound whose six-membered ring contains four carbon atoms and one nitrogen atom and one oxygen atom that lies opposite to each other; the parent compound of the morpholine family.
Morpholine is a saturated organic heteromonocyclic parent and a member of morpholines.
Morpholine is a conjugate base of a morpholinium.
Morpholine is Soluble in acetone, benzene, ether, pentane, methanol, ethanol, carbon tetrachloride, propylene glycol and other organic solvents.
Morpholine vapor could form an explosive mixture with air and the explosion limit is 1.8% to 15.2% (volume fraction).
Morpholine is a secondary amine, and at the same time it has the property of inorganic acid and organic acid, so that it can generate salt and amide.
Morpholine contains secondary amine groups and it has all the typical reaction characteristics of the secondary amine groups.
Morpholine can react with inorganic acid to form a salt, and also can react with organic acid to form salt or amide.

Morpholine can carry out alkylation reactions and it also carry out ketone reaction or Willgerodt reaction with ethylene oxide.
Because of the unique chemical properties of morpholine, it has become one of the important petrochemical products with important commercial application.
Morpholine can be applied to produce rubber vulcanization accelerators such as NOBS, DTOS and MDS.
And Morpholine is also applied to produce anti-corrosives, anti-corrosion agents, detergents, detergents, analgesics, local anesthetics, sedatives, respiratory and vascular stimulants, surfactants, optical bleach, fruit preservatives, and textile dyeing auxiliaries.
Morpholine also has a wide range of applications in the field of rubber, pharmaceuticals, pesticides, dyes, coatings and other industries.
In medication Morpholine could be applied in the production of morpholine guanidine, virus Ling, ibuprofen, cough must, naproxen, dichloroaniline, sodium phenylacetate and other important drugs.

The two main production method of morpholine are DEA method (diethanolamine method) and DEA method (diethylene glycol method)
Morpholine is noteworthy that new polymer monomer acrylic morpholine has obtained a rapid development in recent years.
Acrylic acid morpholine could be produced from the reaction between acrylic acid and morpholine.
And acrylic acid morpholine is a kind of water-soluble monomer, and it is still water-soluble after the polymerization.
So Morpholine could be applied for the modification of aqueous polymers.
Besides, acrylic morpholine is widely used as a reactive diluent for UV curable resins.
With the deepening of applied research, many new specific uses have been developed and Morpholine becomes polymer monomer with rapid development.

As a kind of metal corrosion inhibitor, Morpholine is mainly applied for the anti-corrosion of iron, copper, zinc, lead and other metals.
Morpholine remains at its starting stage in China, but outside the country, a considerable proportion of Morpholine are used as a kind of anti-rust agent for metal gas to prevent the metal corrosion caused by atmosphere and it has been widely used in the field of mechanical instruments, automobiles, medical equipment and others.
The metal atmospheric rust inhibitor used earlier such as dicyclohexylamine nitrite and cyclohexylamine do harm to the human body and they are more environmentally toxic.
Instead, morpholine as a metal gas-liquid corrosion inhibitor, it has the advantages of low toxicity, so the foreground is prosperous.

Morpholine is an organic heteromonocyclic compound whose six-membered ring contains four carbon atoms and one nitrogen atom and one oxygen atom that lies opposite to each other; the parent compound of the morpholine family.
Morpholine is a saturated organic heteromonocyclic parent and a member of morpholines.
Morpholine is a conjugate base of a morpholinium.
An aqueous solution with a fishlike odor.
Corrosive to tissue and moderately toxic by ingestion and inhalation.

Morpholine Chemical Properties
Melting point: -7--5 °C (lit.)
Boiling point: 126.0-130.0 °C 129 °C (lit.)
Density: 0.996 g/mL at 25 °C (lit.)
Vapor density: 3 (vs air)
Vapor pressure: 31 mm Hg ( 38 °C)
Refractive index: n20/D 1.454(lit.)
Fp: 96 °F
Storage temp.: Store below +30°C.
Solubility water: miscible
Form: Liquid
pka: 8.33(at 25℃)
Color: APHA: ≤15
Specific Gravity: 0.996
Odor: Characteristic amine-like odor
PH: 11.2 (H2O)(undiluted)
Explosive limit: 1.4-15.2%(V)
Water Solubility: MISCIBLE
FreezingPoint: -4.9℃
Sensitive: Hygroscopic
Merck: 14,6277
BRN: 102549
Exposure limits: TLV-TWA 20 ppm (~70 mg/m3) (ACGIH, MSHA, and OSHA); STEL skin 30 ppm (ACGIH); IDLH 8000 ppm.
Stability: Stable. Flammable. Incompatible with strong oxidizing agents, strong acids, acid chlorides, acid anhydrides. Hygroscopic.
InChIKey: YNAVUWVOSKDBBP-UHFFFAOYSA-N
LogP: -0.860
CAS DataBase Reference: 110-91-8(CAS DataBase Reference)
NIST Chemistry Reference: Morpholine(110-91-8)
IARC: 3 (Vol. 47, 71) 1999
EPA Substance Registry System: Morpholine (110-91-8)

Morpholine is colorless water-absorbing oily liquid and it smells ammonia.
Morpholine is soluble in water and methanol, ethanol, benzene, acetone, ether, ethylene glycol and other commonly used solvents.
Morpholine is a colorless liquid with a weak ammonia or fish-like odor.
The odor threshold is 0.01 ppm.
The chemical reactivity of morpholine is attributed to the secondary amine function of the molecule; organic condensations, alkylations, and arylations readily occur, with the formation of N-substituted morpholine products of wide diversity.
Ethers are relatively chemically inert, hence the oxygen is of relatively little consequence except as a member of the heterocyclic ring.

Physical properties
Colorless, mobile, oily, hygroscopic, flammable liquid with a weak ammonia-like odor.
Experimentally determined detection and recognition odor threshold concentrations were 40 μg/m3 (11 ppbv) and 25 μg/m3 (70 ppbv), respectively.
Forms explosive vapors at temperatures >35 °C.

Uses
(1) For medicine, Morpholine used as the raw materials for rubber accelerator and fluorescent whitening agent.
(2) Morpholine is the intermediates of fungicide dimethomorph and flumorpholine and organophosphate insecticide phosalphos.
(3) Morpholine is Mainly used for the production of rubber vulcanization accelerator, but also for surfactant, textile auxiliaries, pharmaceuticals, pesticide synthesis.
(4) Morpholine also used as a catalyst for polymerization of butadiene, corrosion inhibitors, optical bleach, the goods are dyes, resins, wax, early glue, casein and other solvents.
At present, the total production of morpholine in the world is 3-4 million t/a.
(5) Morpholine salts are also widely used.
Morpholine salts like morpholine hydrochloride (10024-89-2) are the organic synthesis of intermediates.

Morpholine fatty acid salt can be used as the coating agent of fruits or vegetables epidermal coating agent, and it could inhibit the base respiration and prevent the epidermis from evaporation of water and epidermal atrophy.
(6) Morpholine is the main raw materials of accelerator NOBS. for analysis reagents and resins, wax, shellac and other solvents, used in the production of sodium sulfate.
Water glass and ultramarine.
Also used in the manufacture of glass. Paper. Detergent. Soap. Dye. Synthetic fiber. Tanning. Medicine and ceramics industries.
Analysis reagents, such as nitrogen determination, dehydrating agent.
(7) Morpholine is used for the analysis of reagents and resins, wax, casein, shellac and a variety of solvents solvent.
(8) Morpholine could produce salt after reacting with inorganic acid, and it also could produce salt or amide after reacting with organic acid.
Morpholine also can be alkylated, and it also could come up a ketone reaction or Willgerodt reaction with ethylene oxide.

Industrial uses
The total industrial consumption of morpholine is 11,000 metric tons/year.
The largest usage for morpholine (33%) is in the rubber industry as an intermediate in the production of delayed-action accelerators for the polymerization of rubber, as stabilizers against heat-aging effects, and as bloom inhibitors in butyl rubber vulcanization.
A second large proportion (25%) of morpholine production is used as an inhibitor to combat carbonic acid corrosion in condensate return lines of steam boiler systems.
Morpholine is an intermediate in the manufacture of optical brighteners utilized by the soap and detergent industry.

Morpholine reacts readily with fatty acids, forming soaps used in the formulation of self-polishing waxes and polishes and in coatings for the food industry.
N-methyl morpholine and TV-ethyl morpholine are used as catalysts in the manufacture of polyurethane foams.
Morpholine derivatives are utilized in pharmaceutical applications, as bactericides, fungicides, and herbicides, and as separating agents for oils.
Other derivatives are utilized in the textile and printing industry as adjuvants, whitening agents, stabilizers, ink eradicators, and paper conditioners.

Production method
(1) Morpholine could be produced by diethanolamine dehydration cyclization derived from sulfuric acid.
Add diethanolamine to the water reaction pot and drop sulfuric acid in the temperature of 60 ℃, then when the temperature heat at 185-195 ℃, incubate it for 30min.
Cool Morpholine to under 60℃ and drop sodium hydroxide solution to pH = 11.
The next steeps are cooling, filtering, filtrating distillation, collecting the following fractions below 130℃.
The content of spermine is suppose to reach more than 99.5%.
The method is easy to obtain raw materials, so it has become the main method of producing morpholine in the world. Morpholine also could be produced in the catalytic reaction between dioxane and ammonia gas.

(2) The preparation method is that we could get Morpholine from the presence of sulfuric acid dehydration cyclization diethanolamine.
In the presence of sulfuric acid ; then add diethanolamine into the reaction kettle and add H2SO4 at a temperature of below 6°C, then heat it to 185-195 °C for 30 minutes, cool to 60°C.
Drop NaOH solution to pH = 11, and the last two steeps is cooling and filtrating.
Morpholine could be collected from the fraction below 130 °C.
We can also get morpholine from the reaction between diethylene glycol and ammonia in the presence of catalyst and pressure.
The method is easy to obtain raw materials, thus it is the main method of producing morpholine around the world.

Morpholine is made by dehydrating ethanolamines.
Morpholine's main use is as a rubber accelerator in manufacturing tires.
This process requires high temperature (300°F) and pressure, which increase the hazards.
Morpholine is also used as a boiler water additive, brightener for detergents, and corrosion inhibitor, in the preservation of book paper, in waxes and polishes, and in organic synthesis.
Solvent for resins, waxes, casein, dyes; morpholine compounds used as corrosion inhibitors, insecticides, antiseptics, intermediate for rubber-processing chemicals; corrosion inhibitors; waxes and polishes; optical brighteners.
Rubber accelerator, solvent, additive to boilerwater, waxes and polishes, optical brightener fordetergents, corrosion inhibitor, preservation of bookpaper, organic intermediate (catalyst, antioxidants,pharmaceuticals, bactericides, etc.).

Reactivity Profile
Morpholine dissolved in water neutralizes acids in exothermic reactions to form salts plus water.
May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard
May cause toxic effects if inhaled or ingested/swallowed.
Contact with substance may cause severe burns to skin and eyes.
Fire will produce irritating, corrosive and/or toxic gases.
Vapors may cause dizziness or suffocation.
Runoff from fire control or dilution water may cause pollution.
Morpholine is extremely irritating, causing severe damage to the eyes, mucous membranes, and skin upon contact.
Eye irritation, with transient corneal edema and temporary foggy vision are common symptoms of overexposure to vapors in the workplace.

Morpholine is readily absorbed through the skin; it causes nasal irritation when inhaled, with coughing, bronchial irritation, and pulmonary edema at increasingly higher concentrations.
Upon ingestion, Morpholine causes hemorrhage in the gastrointestinal tract, with possible diarrhea; liver and kidney damage may occur if sufficient amounts are ingested or inhaled.
Morpholine itself is not a carcinogen on the basis of available data.
Morpholine is an irritant to the eyes, skin,and mucous membranes.
The irritant actionsin rabbit eyes and skin were severe.
In humans the inhalation of its vapors cancause visual disturbance, nasal irritation, andcoughing.
High concentrations can producerespiratory distress.

Fire Hazard
Flammable/combustible material.
May be ignited by heat, sparks or flames.
Vapors may form explosive mixtures with air.
Vapors may travel to source of ignition and flash back.
Most vapors are heavier than air.
They will spread along ground and collect in low or confined areas (sewers, basements, tanks).
Vapor explosion hazard indoors, outdoors or in sewers.
Runoff to sewer may create fire or explosion hazard.
Containers may explode when heated.
Many liquids are lighter than water.

Synonyms
MORPHOLINE
110-91-8
1-Oxa-4-azacyclohexane
Diethylene oximide
Tetrahydro-1,4-oxazine
Diethylenimide oxide
Diethyleneimide oxide
Diethylene imidoxide
Drewamine
Tetrahydro-2H-1,4-oxazine
Tetrahydro-p-oxazine
p-Isoxazine, tetrahydro-
morpholin
Tetrahydro-1,4-isoxazine
BASF 238
Caswell No. 584
2H-1,4-Oxazine, tetrahydro-
4H-1,4-Oxazine, tetrahydro-
138048-80-3
NSC 9376
Tetrahydro-p-isoxazine
CCRIS 2482
HSDB 102
EINECS 203-815-1
UNII-8B2ZCK305O
EPA Pesticide Chemical Code 054701
BRN 0102549
8B2ZCK305O
DTXSID2025688
CHEBI:34856
AI3-01231
NSC-9376
MFCD00005972
UN2054
C4H9NO
Tetrahydro-4H-1-4-oxazine
DTXCID305688
EC 203-815-1
4-27-00-00015 (Beilstein Handbook Reference)
Morpholine [UN2054] [Flammable liquid]
MORPHOLINE (IARC)
MORPHOLINE [IARC]
MORPHOLINE-2,2,3,3,5,5,6,6-D8
tetrahydro-14-iso-xazine
1,4-oxazinane
CAS-110-91-8
MORPHOLINE,REAG
MORPHOLINE, PRACT
morphline
Morfolina
Morpholine; Molsidomine Imp. E (EP); Molsidomine Impurity E
morpho line
morpholine-
6LR
MORPHOLINE TECH
4H-1, tetrahydro-
MPL (CHRIS Code)
MORPHOLINE [MI]
MORPHOLINE [FCC]
DIEYTHYLENE OXIMIDE
MORPHOLINE [HSDB]
MORPHOLINE [INCI]
tetra-hydro-1,4-oxazine
Morpholine on Rasta Resin
WLN: T6M DOTJ
NCIMech_000154
Tetrahydro-1, 4-isoxazine
NCIOpen2_007748
Oprea1_317540
Tetryhydro-2H-1,4-oxazine
Tetrahydro-4H-1,4-Oxazine
BIDD:ER0297
Morpholine, analytical standard
CHEMBL276518
NSC9376
AMY22834
BCP24054
STR00194
EINECS 263-172-8
Tox21_202450
Tox21_303240
NA2054
STL182843
TETRAHYDRO-2H-1, 4-OXAZINE
AKOS000118829
Molsidomine Imp. E (EP): Morpholine
Morpholine, ACS reagent, >=99.0%
Morpholine, ReagentPlus(R), >=99%
DB13669
NA 2054
UN 2054
USEPA/OPP Pesticide Code: 054701
NCGC00249227-01
NCGC00256942-01
NCGC00259999-01
61791-40-0
Morpholine, p.a., ACS reagent, 99.0%
Morpholine [UN2054] [Flammable liquid]
FT-0628993
M0465
EN300-18064
Morpholine purified by distillation from glass
Morpholine, purified by redistillation, >=99.5%
Q410243
J-522715
F2190-0339
InChI=1/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H
ScavengePore(TM) phenethyl morpholine, macroporous, 40-70 mesh, extent of labeling: 0.7-1.5 mmol/g loading
StratoSpheres(TM) PL-MPH resin, 50-100 mesh, extent of labeling: 3.0-4.0 mmol/g loading, 1 % cross-linked
MORPHOLINE
Morpholine is an organic chemical compound
Morpholine's chemical formula is O(CH2CH2)2NH.
Morpholine appears as a colorless liquid with


CAS NUMBER: 110-91-8

EC NUMBER: 203-815-1

MOLECULAR FORMULA: C4H9NO

MOLECULAR WEIGHT: 87.12 g/mol

IUPAC NAME: morpholine


Morpholine has a fishlike odor.
Morpholine's flash point is 100 °F.

Morpholine is corrosive to tissue.
Morpholine is less dense than water

Morpholine is soluble in water.
Morpholine's vapors heavier than air

Morpholine is used to make other chemicals
Morpholine is used as a corrosion inhibitor
Morpholine can be used in detergents.

This heterocycle features both amine and ether functional groups.
Because of the amine, morpholine is a base; its conjugate acid is called morpholinium.

For example, treating morpholine with hydrochloric acid makes the salt morpholinium chloride.
Morpholine is a colorless liquid with a weak, ammonia- or fish-like odor.
The naming of morpholine is attributed to Ludwig Knorr, who incorrectly believed it to be part of the structure of morphine

Morpholine is used in washing & cleaning products.
Morpholine is used in building & construction work.

Morpholine is used for the manufacture of chemicals and fabricated metal products.
Morpholine is a synthetic organic liquid used mainly as an intermediate in the production of rubber chemicals and optical brighteners

USES:
Industrial Applications:
Morpholine is a common additive, in parts per million concentrations, for pH adjustment in both fossil fuel and nuclear power plant steam systems.
Morpholine is used because its volatility is about the same as water, so once it is added to the water, its concentration becomes distributed rather evenly in both the water and steam phases.
Morpholine's pH-adjusting qualities then become distributed throughout the steam plant to provide corrosion protection.
Morpholine is often used in conjunction with low concentrations of hydrazine or ammonia to provide a comprehensive all-volatile treatment chemistry for corrosion protection for the steam systems of such plants. Morpholine decomposes reasonably slowly in the absence of oxygen at the high temperatures and pressures in these steam systems.

Organic Synthesis:
Morpholine undergoes most chemical reactions typical for other secondary amines, though the presence of the ether oxygen withdraws electron density from the nitrogen, rendering it less nucleophilic (and less basic) than structurally similar secondary amines such as piperidine.
For this reason, Morpholine forms a stable chloramine.

Morpholine is commonly used to generate enamines.
Morpholine is widely used in organic synthesis.

Morpholine is a colorless hygroscopic liquid with a particular smell (smells like ammonia or fishy smell).
Morpholine is entirely miscible with water, as well as with lots of organic solvents.

Morpholine is an organic chemical compound.
Morpholine is a base because of the amine.
Morpholine's conjugate acid is called morpholinium.

For example, Morpholine is a building block in the preparation of the antibiotic linezolid, the anticancer agent gefitinib (Iressa) and the analgesic dextromoramide.
In research and in industry, the low cost and polarity of morpholine lead to its common use as a solvent for chemical reactions.

Agriculture:
As a fruit coating
Morpholine is used as a chemical emulsifier in the process of waxing fruit.
Naturally, fruits make waxes to protect against insects and fungal contamination, but this can be lost as the fruit is cleaned.
A small amount of new wax is applied to replace it.
Morpholine is used as an emulsifier and solubility aid for shellac, which is used as a wax for fruit coating.

As a component in fungicides
Morpholine derivatives used as agricultural fungicides in cereals are known as ergosterol biosynthesis inhibitors.

*Amorolfine
*Fenpropimorph
*Tridemorph

Morpholine is an organic heteromonocyclic compound whose six-membered ring contains four carbon atoms and one nitrogen atom and one oxygen atom that lies opposite to each other; the parent compound of the morpholine family.
Morpholine is a saturated organic heteromonocyclic parent and a member of morpholines.
Morpholine is a conjugate base of a morpholinium.


PHYSICAL PROPERTIES:

-Molecular Weight: 87.12 g/mol

-XLogP3: -0.9

-Exact Mass: 87.068413911 g/mol

-Monoisotopic Mass: 87.068413911 g/mol

-Topological Polar Surface Area: 21.3Ų

-Physical Description: Colorless liquid with a fishlike odor

-Color: Colorless

-Form: Liquid

-Odor: Weak, ammonia- or fish-like odor

-Boiling Point: 128 °C

-Melting Point: -4.8 °C

-Flash Point: 38 °C

-Solubility in water: miscible

-Density: 1.007

-Vapor Density: 3

-Vapor Pressure: 10.1 mmHg

-Autoignition Temperature: 310 °C

-Viscosity: 2.23 cP

-Surface Tension: 37.5 dynes/cm

-Ionization Potential: 8.88 eV

-Refractive Index: 1.4540


Morpholine is used as an additive for adjusting pH in nuclear power plant steam systems and fossil fuels.
Morpholine is also used for corrosion protection of boiler water stream systems in chemical plants.

Morpholine appears as a colorless liquid
Morpholine has a fishlike odor


CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 1

-Hydrogen Bond Acceptor Count: 2

-Rotatable Bond Count: 0

-Heavy Atom Count: 6

-Formal Charge: 0

-Complexity: 34.5

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 1

-Compound Is Canonicalized: Yes

-Chemical Classes: Nitrogen Compounds -> Morpholines


Morpholine is used for the preparation of alumina catalysts.
They are prepared in the form of a gelling agent for the treatment of hydrocarbons.

Morpholine is commonly used for the synthesis of enamines.
Morpholine is an important ingredient to produce linezolid, which is an antibiotic used for treating infections caused by gram-positive bacteria.

Morpholine's flash point is 100 °F.
Morpholine is corrosive to tissue.

Morpholine is less dense than water
Morpholine is soluble in water

Morpholine is also used in gefitinib, a cancer drug.
Morpholine is also used in the analgesic dextromoramide.
Morpholine salts such as morpholine hydrochloride are used for the organic synthesis of intermediates.

Morpholine in the form of a chemical emulsifier is used for the protection of fruits.
This is achieved through the process of waxing, where a wax layer is applied onto the fruits.
This coating protects fruits from insects and fungal infestation.
Morpholine is widely used as an intermediate in the rubber industry to produce rubber vulcanization accelerators such as DTOS, MDS and NOBS.

Morpholine vapors heavier than air
Morpholine is used to make other chemicals

Morpholine is used as a corrosion inhibitor, and in detergents.
Morpholine is an organic heteromonocyclic compound whose six-membered ring contains four carbon atoms and one nitrogen atom and one oxygen atom that lies opposite to each other; the parent compound of the morpholine family.

Morpholine is a saturated organic heteromonocyclic parent and a member of morpholines.
Morpholine is a conjugate base of a morpholinium.

Morpholine is used in the following products:
-adhesives and sealants
-coating products
-inks and toners
-anti-freeze products
-biocides (e.g. disinfectants, pest control products)
-fuels
-photo-chemicals
-polishes and waxes
-washing & cleaning products
-paper chemicals
-dyes

Morpholine is used as a corrosion inhibitor for metals such as copper, iron, lead, zinc and other metals.
Morpholine is widely used in areas such as automobiles, mechanical instruments and medical equipment.

Morpholine is used in the manufacture of paper, glass, soap, detergent, dye and synthetic fibre.
Morpholine is used to manufacture analysis reagents for nitrogen determination.
Morpholine also finds applications in pharmaceuticals, tanning, textiles, household care and ceramics industries.

Morpholine is an organic compound with both amine and ether groups, obtained by dehydrating diethanolamine with sulphuric acid.
Morpholine can be adapted to many different activities for many important applications.

Morpholine can be used as emulsifiers in waxes and polishes processing industries.
Morpholine is a very good pH adjuster which is very effective for nuclear power plants.
Morpholine can also be used as an ingredient in fungicides and bactericides.


SYNONYMS:

MORPHOLINE
110-91-8
1-Oxa-4-azacyclohexane
Tetrahydro-1,4-oxazine
Diethylene oximide
Diethylenimide oxide
Diethyleneimide oxide
Diethylene imidoxide
Drewamine
Tetrahydro-2H-1,4-oxazine
Tetrahydro-p-oxazine
p-Isoxazine, tetrahydro-
Tetrahydro-1,4-isoxazine
morpholin
BASF 238
2H-1,4-Oxazine, tetrahydro-
4H-1,4-Oxazine, tetrahydro-
138048-80-3
NSC 9376
MFCD00005972
C4H9NO
Tetrahydro-4H-1-4-oxazine
NSC-9376
DTXCID305688
MORPHOLINE-2,2,3,3,5,5,6,6-D8
CAS-110-91-8
CCRIS 2482
HSDB 102
MORPHOLINE,REAG
Tetrahydro-p-isoxazine
MORPHOLINE, PRACT
EINECS 203-815-1
morphline
UNII-8B2ZCK305O
morpho line
morpholine-
AI3-01231
6LR
4H-1, tetrahydro-
Morpholine on Rasta Resin
WLN: T6M DOTJ
EC 203-815-1
NCIMech_000154
Tetrahydro-1, 4-isoxazine
NCIOpen2_007748
Oprea1_317540
Tetryhydro-2H-1,4-oxazine
Tetrahydro-4H-1,4-Oxazine
CHEMBL276518
AKOS000118829
DB13669
NA 2054
UN 2054
NCGC00249227-01
NCGC00256942-01
NCGC00259999-01
61791-40-0
Morpholine, p.a., ACS reagent, 99.0%
DB-030063
Morpholine
FT-0628993
M0465
EN300-18064
Q410243
J-522715
1-Oxa-4-azacyclohexane ; Tetrahydro-2H-1,4-oxazine
MORPHOLINE-2,2,3,3,5,5,6,6-D8 (D, 98%)
tetrahydro 1.4 oxazine
Tetrahydro-1,4-oxazine
Tetrahydro-2H-1,4-oxazine
Tetraidro-1,4-ossazina
4H-1,4-Oxazine, tetrahydro-
Diethylene imidoxide
Diethylene oximide
Diethyleneimide oxide
diethylenimide oxide
Drewamine
Morpholine purified by distillation from glass
Morpholine-d8
N-Vinylbenzylmorpholine-divinylbenzene Copolymer
Tetrahydro-1, 4-isoxazine
Tetrahydro-1,4-isoxazine
Tetrahydro-2H-1,4-oxazine
Tetrahydro-4H-1,4-Oxazine
Tetrahydro-4H-1-4-oxazine
Tetrahydro-P-isoxazine
Tetrahydro-p-oxazine
Tetryhydro-2H-1,4-oxazine
MORPHOLINE
Morpholine is an organic chemical compound having the chemical formula O(CH2CH2)2NH.
This heterocycle features both amine and ether functional groups.
Because of the amine, morpholine is a base; its conjugate acid is called morpholinium.

CAS Number: 110-91-8
EC Number: 203-815-1
Molecular Weight: 87.12 g/mol

For example, treating morpholine with hydrochloric acid makes the salt morpholinium chloride.
Morpholine is a colorless liquid with a weak, ammonia- or fish-like odor.
The naming of morpholine is attributed to Ludwig Knorr, who incorrectly believed it to be part of the structure of morphine.

Morpholine is an important building block for rubber chemicals and finds a multitude of applications in other industries.
Morpholine is used as an intermediate for water treatment, the production of pharmaceutical and agrocultural products as well as optical brightners.


Morpholine appears as a colorless liquid with a fishlike odor.
Flash point of Morpholine is 100 °F.
Morpholine is Corrosive to tissue.

Morpholine is Less dense than water and soluble in water.
Vapors of Morpholine is heavier than air.
Morpholine is Used to make other chemicals, as a corrosion inhibitor, and in detergents.
Morpholine is an organic heteromonocyclic compound whose six-membered ring contains four carbon atoms and one nitrogen atom and one oxygen atom that lies opposite to each other; the parent compound of the morpholine family.
Morpholine is a saturated organic heteromonocyclic parent and a member of morpholines.
Morpholine is a conjugate base of a morpholinium.

PRODUCTION OF MORPHOLINE:
Morpholine is often produced industrially by the dehydration of diethanolamine with sulfuric acid.
The major process for the production of morpholine until the early 1970s was the acidcatalysed dehydration of diethanolamine.
This process has largely been replaced by a process based on the reaction of diethylene glycol with ammonia at high temperatures and pressures, with or without a catalyst.

Typically, diethylene glycol and ammonIa are combined in the presence of hydrogen and a catalyst at a temperature between 150-400°C and a pressure between 3-4 MPa (30-400 atm).
The hydrogenation catalyst may be any one of a number of metals.
Excess ammonia is stripped from the crude reaction mixure, and morpho line is obtained by fractional distilation.

Production of morpholine in the USA in 1981 was estimated to be in the range of 1300 tonnes - about 40% higher than output ten years earlier.
Imports to the USA may have been about 1100160 tonnes per year in the late 1970s; in 1981, they were reported to be in the range of 700 tonnes.
About 1400 tonnes per year are exprted from the USA.

USES OF MORPHOLINE:
Industrial applications:
Morpholine is a common additive, in parts per million concentrations, for pH adjustment in both fossil fuel and nuclear power plant steam systems.
Morpholine is used because its volatility is about the same as water, so once it is added to the water, its concentration becomes distributed rather evenly in both the water and steam phases.

Its pH-adjusting qualities then become distributed throughout the steam plant to provide corrosion protection.
Morpholine is often used in conjunction with low concentrations of hydrazine or ammonia to provide a comprehensive all-volatile treatment chemistry for corrosion protection for the steam systems of such plants.
Morpholine decomposes reasonably slowly in the absence of oxygen at the high temperatures and pressures in these steam systems.

Organic synthesis:
Morpholine undergoes most chemical reactions typical for other secondary amines, though the presence of the ether oxygen withdraws electron density from the nitrogen, rendering Morpholine less nucleophilic (and less basic) than structurally similar secondary amines such as piperidine.
For this reason, Morpholine forms a stable chloramine.
Morpholine is commonly used to generate enamines.

Morpholine is widely used in organic synthesis.
For example, Morpholine is a building block in the preparation of the antibiotic linezolid, the anticancer agent gefitinib (Iressa) and the analgesic dextromoramide.
In research and in industry, the low cost and polarity of morpholine lead to its common use as a solvent for chemical reactions.

Agriculture:
As a fruit coating:
Morpholine is used as a chemical emulsifier in the process of waxing fruit.
Naturally, fruits make waxes to protect against insects and fungal contamination, but this can be lost as the fruit is cleaned.

A small amount of new wax is applied to replace Morpholine.
Morpholine is used as an emulsifier and solubility aid for shellac, which is used as a wax for fruit coating.
The European Union has forbidden the use of morpholine in fruit coating.

As a component in fungicides:
Morpholine derivatives used as agricultural fungicides in cereals are known as ergosterol biosynthesis inhibitors.
• Amorolfine
• Fenpropimorph
• Tridemorph

Morpholine is tyically used as follows: rubber chemicals, 40%; corrosion inhibitors,
30%; waxes and polishes, 5%; optical brighteners, 5%; and miscellaneous, 20%.

Rubber chemicals:
Morpholine is an important intermediate for rubber-processing chemicals, especially in the production of delayed-action rubber accelerators, which are added durig the vulcanization process to reduce the possibilty of prevulcaniztion durig the mixg stages of fabrication.
Morpholine-derived sulfur compounds give a high rate of cure durig vulcaniztion, with a reduced tendency to overcure.
These include morpholinium N,N-oxydiethylenedithiocrbamate and 2-(N-morpholinothio )benzothiazole. Morpholine derivatives, such as
N,N' -dithiodimorpholine and N,N' -tetrathiodimorpholine, are also used to stabilize halogenated butyl rubber against heat-ageing effects.
Corrosion control:
Morpholineis used to control corrosion in steam condensate systems.
Morpholine neutralizes carbon dioxide and other corrosive acid components in steam and condensate, aids in maintaining the proper pH throughout the system, has a suitable vapour pressure and aqueous solubilty, and is stable at temperatures up to 288°C.

Morpholine and its salts with fatty acids from animal and vegetable oils may be used as corrosion inhibitors for steel or tin plate to be used in contact with foo.
Morpholine has been used as a corrosion inhibitor in the natural gas and pipeline industiy.

Wax and polishes:
Morpholine reacts readily with fatty acids, forming emulsifg agents, which are used in the formulation of water-resistant waxes and polishes for automobiles, fIoors, leather and furniture.
As the fim of polish emulsion gradually dries, morpholine evaporates to form a fim highly resistant to waterspotting and deterioration.

An example of this tye of polish is a carnauba wax formulation with the followig composition (in parts by weight): carnauba wax, 11.2; oleic acid, 2.4; morpholine, 2.2; water, 67.0. A tyical silcone automobile polish-cleaner is composed as follows (in parts by weight): silcone fIuid, 4.0; oleic acid, 2.5; morpholine, 1.5; Stoddard solvent (see the monograph on sorne petroleum solvents, p. ), 19; kerosene (deodouried), 2; water, 57; abrasive, 14.
The followig formulation is representative of silcone-cntaining furniture polishes (in parts by weight): silcone fIuid, 5.0; VM & P naphtha (see the monograph on some petroleum solvents, p. 43) (high flash), 30.0; oleic acid, 2.5; morpholine, 1.5; water, 60.6; water-soluble resin, 0.4.

Optical brighteners:
Morpholine is an importnt intermediate in the manufacture of optical brighteners.
The diaminostilbene trizine tye brightener with morpholine as a substituent on one of the triazine rigs is used in home laundiy detergents since it is stable to chlorie bleaches.

Miscellaneous:
Morpholine and its salts have been reported to be used as components of protective coatings applied on fruits and vegetables.

The compound has been used in the preparation of pharmaceuticals, including such diverse products as analgesics, locl anaesthetics, respiratoiy and circulatoiy stimulants, antispasmodics and soluble sulfanilamides.
Morpholine derivatives have been used widely in the textile industiy, as softening agents for cellulosic fibrès, ingredients of rayon spinning baths, sizing emulsifiers, textile lubricants, whitening agents and dyes.
Cosmetic products that may incorpra te morpholine-based compounds include hair conditioners, deodorants, shampos, mouthwashes and cosmetic creams.

Stabilizers and antioxidants for lubricating oils, soluble oils for cutting tools and carbn remover compounds have been prepared from morpholine.
This compound has a high selectivity and solvency for aromaties and can be used to extract benzene, toluene and xylene economically from petroleum feedstock.
Other products sythesized from morpholine include ion-exchange resins, dyes for electrolytic recording inks and photographic chemicals.

APPLICATIONS OF MORPHOLINE:
Morpholine may be used in the preparation of derivatives such as 4-benzoyloxymorpholine and 1-morpholinopropan-1-one.
Morpholine may also be used in the preparation of (S)-3,3′-bis-morpholinomethyl-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-bi-2-naphthol, a bifunctional chiral catalyst for asymmetric synthesis.
As a base, morpholine can be used in the preparation of 1,3-disubstituted allenes from terminal alkynes and aldehydes.

Morpholine can be used as a buffer component in the separation of peptides and pathogenic lipopolysaccharides during on-line chromatographic preconcentration coupled to capillary zone electrophoresis–electrospray mass spectrometry (cPC–CZE–ES-MS) analysis from colony isolates.

SAFETY INFORMATION ABOUT MORPHOLINE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product

CHEMICAL AND PHYSICAL PROPERTIES OF MORPHOLINE:
Chemical formula C4H9NO
Molar mass 87.122 g•mol−1
Appearance Colorless liquid
Odor Weak ammonia-like or fish-like[3]
Density 1.007 g/cm3
Melting point −5 °C (23 °F; 268 K)
Boiling point 129 °C (264 °F; 402 K)
Solubility in water miscible
Vapor pressure 6 mmHg (20 °C)[3]
Acidity (pKa) 8.36[4] (of conjugate acid)
Magnetic susceptibility (χ) -55.0•10−6 cm3/mol
Chemical Formula: C4H9NO
Flash Point: 100°F
Lower Explosive Limit (LEL): 1.8 %
Upper Explosive Limit (UEL): 10.8 %
Autoignition Temperature: 590°F
Melting Point: 23.2°F
Vapor Pressure: 6.6 mmHg at 68°F
Vapor Density (Relative to Air): 3
Specific Gravity: 1 at 68°F
Boiling Point: 264°F at 760 mmHg
Molecular Weight: 87.12
Water Solubility: Soluble
Ionization Energy/Potential: 8.88 eV
IDLH: 1400 ppm ; Based on 10% of the lower explosive limit.
Grade: ACS reagent
Quality Level: 200
vapor density: 3 (vs air)
vapor pressure:
31 mmHg ( 38 °C)
7 mmHg ( 20 °C)
Assay: ≥99.0%
Form: liquid
autoignition temp.: 590 °F
expl. lim.: 10.8 %
color: APHA: ≤15
refractive index: n20/D 1.454 (lit.)
Boiling point 129 °C (1013 hPa)
Density 1.000 g/cm3 (20 °C)
Explosion limit 1.4 - 15.2 %(V)
Flash point 32 °C
Ignition temperature 275 °C
Melting Point -7 - -5 °C
pH value 10.6 (5 g/l, H₂O, 20 °C) (undiluted)
Vapor pressure 9.33 hPa (20 °C)
Viscosity kinematic 2.2 mm2/s (20 °C)
Molecular Weight 87.12 g/mol
XLogP3 -0.9
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 0
Exact Mass 87.068413911 g/mol
Monoisotopic Mass 87.068413911 g/mol
Topological Polar Surface Area 21.3Ų
Heavy Atom Count 6
Formal Charge 0
Complexity 34.5
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

OTHER NAMES:
Diethylenimide oxide
1,4-Oxazinane
Tetrahydro-1,4-oxazine
Diethylene imidoxide
Diethylene oximide
Tetrahydro-p-oxazine


SYNONYMS OF MORPHOLINE:
102549 [Beilstein]
110-91-8 [RN]
203-815-1 [EINECS]
8B2ZCK305O
MFCD00005972 [MDL number]
Morfolina [Italian]
Morfolina [Portuguese]
Morpholin [German] [ACD/IUPAC Name]
Morpholine [ACD/Index Name] [ACD/IUPAC Name] [Wiki]
Morpholine [French] [ACD/Index Name] [ACD/IUPAC Name]
QD6475000
Tetrahydro-1,4-oxazine
UNII:8B2ZCK305O
Морфолин [Russian]
モルホリン [Japanese]
吗啉 [Chinese]
吗啡啉 [Chinese]
(2H9)Morpholine [ACD/IUPAC Name]
1,4-Oxazinane
134071-14-0 [RN]
138048-80-3 [RN]
175591-17-0 [RN]
1-Oxa-4-azacyclohexane
203578-31-8 [RN]
2H-1,4-Oxazine, tetrahydro-
4-27-00-00015 (Beilstein Handbook Reference) [Beilstein]
4H-1,4-Oxazine, tetrahydro-
Diethylene imidoxide
Diethylene oximide
Diethyleneimide oxide
diethylenimide oxide
Drewamine
m
Morpholine purified by distillation from glass
Morpholine-d8
N-Vinylbenzylmorpholine-divinylbenzene Copolymer
Oprea1_317540
p-Isoxazine, tetrahydro-
ST5213815
STR00194
T6M DOTJ [WLN]
Tetrahydro-1, 4-isoxazine
Tetrahydro-1,4-isoxazine
Tetrahydro-2H-1,4-oxazine
Tetrahydro-4H-1,4-Oxazine
Tetrahydro-4H-1-4-oxazine
Tetrahydro-P-isoxazine
Tetrahydro-p-oxazine
Tetryhydro-2H-1,4-oxazine
UN 2054
UNII-8B2ZCK305O
WLN: T6M DOTJ
morpholine
morpholine hydrochloride
morpholine hydroiodide
morpholine phosphate
morpholine phosphate (3:1)
morpholine phosphonate (1:1)
morpholine sulfite (1:1)
MORPHOLINE
110-91-8
1-Oxa-4-azacyclohexane
Tetrahydro-1,4-oxazine
Diethylene oximide
Diethylenimide oxide
Diethyleneimide oxide
Diethylene imidoxide
Drewamine
Tetrahydro-2H-1,4-oxazine
Tetrahydro-p-oxazine
p-Isoxazine, tetrahydro-
Tetrahydro-1,4-isoxazine
morpholin
BASF 238
Caswell No. 584
2H-1,4-Oxazine, tetrahydro-
4H-1,4-Oxazine, tetrahydro-
138048-80-3
NSC 9376
MFCD00005972
C4H9NO
Tetrahydro-4H-1-4-oxazine
8B2ZCK305O
DTXSID2025688
CHEBI:34856
NSC-9376
DTXCID305688
MORPHOLINE-2,2,3,3,5,5,6,6-D8
CAS-110-91-8
CCRIS 2482
HSDB 102
MORPHOLINE,REAG
Tetrahydro-p-isoxazine
MORPHOLINE, PRACT
EINECS 203-815-1
UN2054
EPA Pesticide Chemical Code 054701
BRN 0102549
morphline
UNII-8B2ZCK305O
morpho line
morpholine-
AI3-01231
6LR
4H-1, tetrahydro-
MORPHOLINE [MI]
Morpholine [UN2054] [Flammable liquid]
Morpholine Reagent Grade
MORPHOLINE [FCC]
MORPHOLINE [HSDB]
MORPHOLINE [IARC]
MORPHOLINE [INCI]
Morpholine on Rasta Resin
WLN: T6M DOTJ
EC 203-815-1
NCIMech_000154
Tetrahydro-1, 4-isoxazine
NCIOpen2_007748
Oprea1_317540
Tetryhydro-2H-1,4-oxazine
Tetrahydro-4H-1,4-Oxazine
4-27-00-00015 (Beilstein Handbook Reference)
BIDD:ER0297
Morpholine, analytical standard
CHEMBL276518
NSC9376
AMY22834
BCP24054
STR00194
Tox21_202450
Tox21_303240
STL182843
AKOS000118829
Morpholine, ACS reagent, >=99.0%
Morpholine, ReagentPlus(R), >=99%
DB13669
NA 2054
UN 2054
NCGC00249227-01
NCGC00256942-01
NCGC00259999-01
61791-40-0
Morpholine, p.a., ACS reagent, 99.0%
DB-030063
Morpholine [UN2054] [Flammable liquid]
FT-0628993
M0465
EN300-18064
Morpholine purified by distillation from glass
Morpholine, purified by redistillation, >=99.5%
Q410243
J-522715
1-Oxa-4-azacyclohexane ; Tetrahydro-2H-1,4-oxazine
F2190-0339
ScavengePore(TM) phenethyl morpholine, macroporous, 40-70 mesh, extent of labeling: 0.7-1.5 mmol/g loading
StratoSpheres(TM) PL-MPH resin, 50-100 mesh, extent of labeling: 3.0-4.0 mmol/g loading, 1 % cross-linked


MORPHOLINE (1,4-OXAZINANE)
Morpholine (1,4-Oxazinane) is an organic heteromonocyclic compound whose six-membered ring contains four carbon atoms and one nitrogen atom and one oxygen atom that lies opposite to each other; the parent compound of the morpholine family.
Morpholine (1,4-Oxazinane) , also known as diethylenimine oxide, is a kind of colorless alkaline oily liquid.
Morpholine (1,4-Oxazinane) smells of ammonia and has hygroscopicity.

CAS Number: 110-91-8
Molecular Formula: C4H9NO
Molecular Weight: 87.12
EINECS Number: 203-815-1

MORPHOLINE, 110-91-8, 1-Oxa-4-azacyclohexane, Diethylene oximide, Tetrahydro-1,4-oxazine, Diethylenimide oxide, Diethyleneimide oxide, Diethylene imidoxide, Drewamine, Tetrahydro-2H-1,4-oxazine, Tetrahydro-p-oxazine, p-Isoxazine, tetrahydro-, morpholin, Tetrahydro-1,4-isoxazine, BASF 238, Caswell No. 584, 2H-1,4-Oxazine, tetrahydro-, 4H-1,4-Oxazine, tetrahydro-, 138048-80-3, NSC 9376, Tetrahydro-p-isoxazine, CCRIS 2482, HSDB 102, EINECS 203-815-1, UNII-8B2ZCK305O, EPA Pesticide Chemical Code 054701, BRN 0102549, 8B2ZCK305O, DTXSID2025688, CHEBI:34856, AI3-01231, NSC-9376, MFCD00005972, C4H9NO, Tetrahydro-4H-1-4-oxazine, DTXCID305688, EC 203-815-1, 4-27-00-00015 (Beilstein Handbook Reference), MORPHOLINE (IARC), MORPHOLINE [IARC], MORPHOLINE-2,2,3,3,5,5,6,6-D8, tetrahydro-14-iso-xazine, 1,4-oxazinane, CAS-110-91-8, MORPHOLINE,REAG, MORPHOLINE, PRACT, UN2054, morphline, Morpholine; Molsidomine Imp. E (EP); Molsidomine Impurity E, morpho line, morpholine-6LR, Morpholine (BASF), 4H-1, tetrahydro-, MORPHOLINE [MI], Morpholine [UN2054] [Flammable liquid], MORPHOLINE [FCC], DIEYTHYLENE OXIMIDE, MORPHOLINE [HSDB], MORPHOLINE [INCI], Morpholine on Rasta Resin, WLN: T6M DOTJ, NCIMech_000154, Tetrahydro-1, 4-isoxazine, NCIOpen2_007748, Oprea1_317540, Tetryhydro-2H-1,4-oxazine, Tetrahydro-4H-1,4-Oxazine, BIDD:ER0297, Morpholine, analytical standard, CHEMBL276518, NSC9376, AMY22834, BCP24054, STR00194, Tox21_202450, Tox21_303240, TETRAHYDRO-2H-1, 4-OXAZINE, AKOS000118829, Morpholine, ACS reagent, >=99.0%, Morpholine, ReagentPlus(R), >=99.0%, DB13669, NA 2054, UN 2054, USEPA/OPP Pesticide Code: 054701, NCGC00249227-01, NCGC00256942-01, NCGC00259999-01, Morpholine, p.a., ACS reagent, 99.0%, Morpholine [UN2054] [Flammable liquid], FT-0628993, M0465, EN300-18064, Morpholine purified by distillation from glass, Morpholine, purified by redistillation, >=99.5%, Q410243, J-522715, F2190-0339, InChI=1/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H, ScavengePore(TM) phenethyl morpholine, macroporous, 40-70 mesh, extent of labeling: 0.7-1.5 mmol/g loading, StratoSpheres(TM) PL-MPH resin, 50-100 mesh, extent of labeling: 3.0-4.0 mmol/g loading, 1 % cross-linked

Morpholine (1,4-Oxazinane) could evaporate with water vapor and miscible with water.
Morpholine (1,4-Oxazinane) is Soluble in acetone, benzene, ether, pentane, methanol, ethanol, carbon tetrachloride, propylene glycol and other organic solvents.
Morpholine (1,4-Oxazinane) Vapor could form an explosive mixture with air and the explosion limit is 1.8% to 15.2% (volume fraction).

Morpholine (1,4-Oxazinane) helps protect metal surfaces from corrosion.
Morpholine (1,4-Oxazinane) is sometimes used in water treatment formulations for cooling and heating systems to prevent corrosion and scale formation.
Besides, acrylic Morpholine (1,4-Oxazinane) is widely used as a reactive diluent for UV curable resins.

Morpholine (1,4-Oxazinane) is employed in gas scrubbing processes to remove acidic impurities, such as hydrogen sulfide, from industrial gases.
Morpholine (1,4-Oxazinane) is a secondary amine, and at the same time it has the property of inorganic acid and organic acid, so that it can generate salt and amide.
Morpholine (1,4-Oxazinane) contains secondary amine groups and it has all the typical reaction characteristics of the secondary amine groups.

Morpholine (1,4-Oxazinane) can react with inorganic acid to form a salt, and also can react with organic acid to form salt or amide.
Morpholine (1,4-Oxazinane) is a cyclic amine that consists of a six-membered ring containing both oxygen and nitrogen atoms.
Morpholine (1,4-Oxazinane) is known for its corrosion-inhibiting properties, making it useful in various industries, such as the production and transportation of water and steam.

Morpholine (1,4-Oxazinane) is a saturated organic heteromonocyclic parent and a member of morpholines.
Morpholine (1,4-Oxazinane) is a heterocyclic organic compound with the molecular formula C4H9NO.
In Morpholine (1,4-Oxazinane) , the term "technical grade" typically refers to a product that may not meet the high purity standards required for laboratory or
pharmaceutical use but is suitable for various industrial applications.

Morpholine (1,4-Oxazinane) is used as a catalyst in the production of rubber and polymers.
Morpholine (1,4-Oxazinane) helps control the molecular weight and structure of polymer products.
In the textile industry, Morpholine (1,4-Oxazinane) can be used as a solvent in dyeing processes and as a stabilizer for dyes.

Morpholine (1,4-Oxazinane) may be added to gasoline and lubricants to inhibit corrosion in engines and fuel systems.
Morpholine (1,4-Oxazinane) is an organic chemical compound having the chemical formula O(CH2CH2)2NH.
This heterocycle features both amine and ether functional groups.

Because of the amine, Morpholine (1,4-Oxazinane) is a base; its conjugate acid is called morpholinium.
For example, treating Morpholine (1,4-Oxazinane) with hydrochloric acid makes the salt morpholinium chloride.
Morpholine (1,4-Oxazinane) is a colorless liquid with a weak, ammonia- or fish-like odor.

Morpholine (1,4-Oxazinane) is attributed to Ludwig Knorr, who incorrectly believed it to be part of the structure of morphine.
Morpholine (1,4-Oxazinane) is colorless water-absorbing oily liquid and it smells ammonia.
Morpholine (1,4-Oxazinane) is soluble in water and methanol, ethanol, benzene, acetone, ether, ethylene glycol and other commonly used solvents.

Morpholine (1,4-Oxazinane) is a colorless to yellow liquid with a weak ammonia or fish-like odor.
The reactivity of Morpholine (1,4-Oxazinane) is mainly due to its secondary amine group.
Morpholine (1,4-Oxazinane) readily undergoes organic condensations, alkylations, and arylations, resulting in the formation of various N-substituted morpholine compounds.

Ethers are relatively chemically inert, hence the oxygen is of relatively little consequence except as a member of the heterocyclic ring.
Morpholine (1,4-Oxazinane) , Reagent, ACS is used as an industrial pH modifier and corrosion inhibitor.
Morpholine (1,4-Oxazinane) is also used as organic synthetic building block and a laboratory solvent.

As an ACS grade quality reagent, Morpholine (1,4-Oxazinane) is chemical specifications are the de facto standards for chemicals used in many high-purity applications and typically designate the highest quality chemical available for laboratory use.
Spectrum Chemical manufactured Reagent ACS grade products meet the toughest regulatory standards for quality and purity.
Morpholine (1,4-Oxazinane) is a volatile organic chemical compound with the chemical formula C4H9NO.

Morpholine (1,4-Oxazinane) has the properties of two functional groups, amine and ether.
In fact, Morpholine (1,4-Oxazinane) is a chemically stable amino ether. Due to the presence of amines, morpholine is a base whose conjugated acid is morpholinium.
While higher-purity grades are used in pharmaceuticals, technical grade morpholine may find application in certain aspects of pharmaceutical manufacturing.

Morpholine (1,4-Oxazinane) can be used in the formulation of adhesives and sealants to improve performance and stability.
Morpholine (1,4-Oxazinane) is widely used in the production of many chemicals as a corrosion inhibitor and also in detergents.
Shanghai Chemex is one of the most reputable suppliers of this chemical in the world.

Morpholine (1,4-Oxazinane) is a colorless liquid with a fishy odor that has a flashpoint of 100 degrees Fahrenheit and is corrosive to tissues, soluble in water, and denser than water.
Morpholine (1,4-Oxazinane) is soluble in acetone, benzene, ether, pentane, methanol, ethanol, carbon tetrachloride, propylene glycol, and other organic solvents, and its vapors are heavier than air and can form explosive mixtures with air.
The most important application of morpholine is as an intermediate in the production of accelerators used in the rubber industry.

Accelerators will be added to the rubber before production to speed up vulcanization.
Another application of this chemical compound is in medicine and the pharmaceutical industry.
Morpholine (1,4-Oxazinane) is used to produce a variety of local anesthetics, sedatives, analgesics, vascular and respiratory stimulants.

Morpholine (1,4-Oxazinane) is an extremely versatile chemical with many important applications.
Morpholine (1,4-Oxazinane) is used as an intermediate in the manufacture of rubber chemicals and optical brighteners.
Morpholine (1,4-Oxazinane) is also used extensively as a corrosion inhibitor in steam boiler systems.

Morpholine (1,4-Oxazinane) is often used as a solvent in various industrial processes, such as the extraction of natural gas and the purification of pharmaceuticals.
Morpholine (1,4-Oxazinane) is employed as a corrosion inhibitor in steam boiler systems and other water-based cooling systems to help prevent corrosion of metal components.
So Morpholine (1,4-Oxazinane) could be applied for the modification of aqueous polymers.

Morpholine (1,4-Oxazinane) is a heterocyclic organic compound with the chemical formula C4H9NO.
Morpholine (1,4-Oxazinane) is a conjugate base of a morpholinium.
Morpholine (1,4-Oxazinane) is used in the production of adhesives and sealants.

Morpholine (1,4-Oxazinane) is utilized in the natural gas industry for sweetening, which involves removing hydrogen sulfide and carbon dioxide from natural gas streams.
Morpholine (1,4-Oxazinane) can be found in some formulations of paints and coatings as a stabilizer or pH adjuster.
Technical-grade Morpholine (1,4-Oxazinane) refers to morpholine that is produced and used for industrial purposes, typically in applications where high purity is not a critical requirement.

Morpholine (1,4-Oxazinane) is a colorless, hygroscopic liquid free of suspended matter.
Morpholine (1,4-Oxazinane) is fully miscible with water and almost all common organic solvents, and slightly soluble in aliphatic hydrocarbons.
Morpholine (1,4-Oxazinane) is generally used as a chemical intermediate in corrosion inhibitors for steam boiler systems, but also has uses in pharmaceuticals,
textiles, rubbers, catalysts, plasticizers, dyes, and agricultural and photographic chemicals.

Morpholine (1,4-Oxazinane) can carry out alkylation reactions and it also carry out ketone reaction or Willgerodt reaction with ethylene oxide.
Because of the unique chemical properties of Morpholine (1,4-Oxazinane) , it has become one of the important petrochemical products with important commercial application.
Morpholine (1,4-Oxazinane) can be applied to produce rubber vulcanization accelerators such as NOBS, DTOS and MDS.

Morpholine (1,4-Oxazinane) is also applied to produce anti-corrosives, anti-corrosion agents, detergents, detergents, analgesics, local anesthetics, sedatives, respiratory and vascular stimulants, surfactants, optical bleach, fruit preservatives, and textile dyeing auxiliaries.
Morpholine (1,4-Oxazinane) also has a wide range of applications in the field of rubber, pharmaceuticals, pesticides, dyes, coatings and other industries.
In medication it could be applied in the production of Morpholine (1,4-Oxazinane) , virus Ling, ibuprofen, cough must, naproxen, dichloroaniline, sodium phenylacetate and other important drugs.

The two main production method of Morpholine (1,4-Oxazinane) are DEA method (diethanolamine method) and DEA method (diethylene glycol method).
Morpholine (1,4-Oxazinane) is noteworthy that new polymer monomer acrylic morpholine has obtained a rapid development in recent years.
Morpholine (1,4-Oxazinane) is used in the rubber industry as an intermediate for the production of accelerators and as a curing agent.

Due to its favorable thermal stability and low freezing point, Morpholine (1,4-Oxazinane) is employed in heat transfer fluids in various industrial processes.
Morpholine (1,4-Oxazinane) is used in metal cleaning processes, particularly for removing rust and scale from metal surfaces.
Morpholine (1,4-Oxazinane) is employed as a building block in the synthesis of certain pharmaceuticals and agrochemicals.

Morpholine (1,4-Oxazinane) can be used in the paper and pulp industry as an additive in the pulping process.
Morpholine (1,4-Oxazinane) is used in the textile industry for printing and dyeing processes.
Due to its ability to inhibit corrosion, Morpholine (1,4-Oxazinane) is added to cooling and antifreeze fluids in some applications.

In laboratories, Morpholine (1,4-Oxazinane) can be used as a reagent in chemical synthesis and analysis.
Morpholine (1,4-Oxazinane) derivatives are sometimes employed in biomedical research for their potential pharmacological activities.
Morpholine (1,4-Oxazinane) can function as a plasticizer in the production of certain plastics.

Morpholine (1,4-Oxazinane) serves as an intermediate in the synthesis of other chemicals.
Morpholine (1,4-Oxazinane) can be used in the production of rubber accelerators, optical brighteners, and certain pharmaceuticals.
Morpholine (1,4-Oxazinane) is sometimes used as a pH regulator in water treatment processes.

In some polymerization processes, Morpholine (1,4-Oxazinane) can be used as a catalyst or an aid to control the polymerization reaction.
Morpholine (1,4-Oxazinane) is used in gas scrubbing systems to remove acidic components, such as hydrogen sulfide, from gas streams.
Morpholine (1,4-Oxazinane) is mainly applied for the anti-corrosion of iron, copper, zinc, lead and other metals.

Morpholine (1,4-Oxazinane) remains at its starting stage in China, but outside the country, a considerable proportion of Morpholine are used as a kind of anti-rust agent for metal gas to prevent the metal corrosion caused by atmosphere and it has been widely used in the field of mechanical instruments, automobiles, medical equipment and others.
The metal atmospheric rust inhibitor used earlier such as dicyclohexylamine nitrite and cyclohexylamine do harm to the human body and they are more environmentally toxic.
Morpholine (1,4-Oxazinane) finds application in the textile industry as a catalyst for the production of certain dyes and as a stabilizer for emulsions.

Morpholine (1,4-Oxazinane) is often used in a range of industrial processes and applications due to its chemical properties.
Morpholine (1,4-Oxazinane) is a colorless, amine-like liquid with a characteristic odor.
Morpholine (1,4-Oxazinane) consists of a six-membered ring containing both nitrogen and oxygen atoms.

Morpholine (1,4-Oxazinane) is a colorless, amine-like liquid with a characteristic amine odor.
Morpholine (1,4-Oxazinane) could be produced from the reaction between acrylic acid and morpholine.
Morpholine (1,4-Oxazinane) is a kind of water-soluble monomer, and it is still water-soluble after the polymerization.

Melting point: -7--5 °C (lit.)
Boiling point: 126.0-130.0 °C 129 °C (lit.)
Density: 0.996 g/mL at 25 °C (lit.)
vapor density: 3 (vs air)
vapor pressure: 31 mm Hg ( 38 °C)
refractive index: n20/D 1.454(lit.)
Flash point: 96 °F
storage temp.: Store below +30°C.
solubility: water: miscible
form: Liquid
pka: 8.33(at 25℃)
color: APHA: ≤15
Specific Gravity: 0.996
Odor: Characteristic amine-like odor
PH: 11.2 (H2O)(undiluted)
explosive limit: 1.4-15.2%(V)
Water Solubility: MISCIBLE
FreezingPoint: -4.9℃
Sensitive: Hygroscopic
Dielectric constant: 7.3(25℃)
LogP: -0.860

Morpholine (1,4-Oxazinane) is a chemical intermediate used in the production of pharmaceuticals, agrochemicals, and surfactants.
This 97% pure technical grade compound is typically used for research purposes.
Morpholine (1,4-Oxazinane) should be handled with care as it may cause skin irritation or eye damage upon contact.

May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Morpholine (1,4-Oxazinane) did not produce an increase in tumors in rats that inhaled from 10 to 150 ppm for 2 years.

No tumors were seen in rats fed 5000 ppm Morpholine (1,4-Oxazinane) for 8 weeks and observed for their lifetime.
Morpholine (1,4-Oxazinane) fed concurrently with sodium nitrate increased the numbers of hepatocellular carcinomas and sarcomas of the liver and lungs of rats and mice, probably mediated through the formation of N-nitrosomorpholine.
Morpholine (1,4-Oxazinane) is used in water treatment processes to control pH and prevent corrosion in water systems.

Morpholine (1,4-Oxazinane) finds applications in electroplating processes, where it can be used as a buffering agent.
Morpholine (1,4-Oxazinane) is utilized in the production of certain types of inks as a stabilizer and pH regulator.
Morpholine (1,4-Oxazinane) is sometimes used as an additive in gasoline to improve combustion efficiency.

Morpholine (1,4-Oxazinane) derivatives are employed in the synthesis of herbicides and pesticides.
Morpholine (1,4-Oxazinane) derivatives can be used in the manufacture of photographic chemicals.
In the oil and gas industry, Morpholine (1,4-Oxazinane) is sometimes employed as a scavenger for hydrogen sulfide.

Morpholine (1,4-Oxazinane) can be used in the leather industry as a dyeing assistant.
Morpholine (1,4-Oxazinane) can be involved in processes related to the desulfurization of gasoline.
Morpholine (1,4-Oxazinane) may be used as an additive in coolant formulations for specific applications.

In natural gas storage, Morpholine (1,4-Oxazinane) can be employed to prevent corrosion in storage tanks and pipelines.
Morpholine (1,4-Oxazinane) derivatives can be used in certain polymerization processes for cross-linking polymers.
Morpholine (1,4-Oxazinane) is used in cooling water treatment to control corrosion and scale formation in cooling systems.

In the cosmetics industry, Morpholine (1,4-Oxazinane) is sometimes used as a humectant to retain moisture in certain formulations.
Morpholine (1,4-Oxazinane) derivatives have been investigated for their antifungal properties and may find applications in antifungal formulations.
Morpholine (1,4-Oxazinane) can be added to deicing fluids to enhance their performance in preventing ice formation on surfaces.

Morpholine (1,4-Oxazinane) derivatives may be used in the production of certain materials for photovoltaic devices.
Morpholine (1,4-Oxazinane) can be added to gasoline formulations to reduce vapor pressure, which is important for controlling emissions.
Morpholine (1,4-Oxazinane) is used as a curing agent for epoxy resins, contributing to the formation of a solid and durable material.

Morpholine (1,4-Oxazinane) derivatives can be involved in the synthesis of certain fertilizers.
Morpholine (1,4-Oxazinane) may be used as an additive in detergent formulations for its stabilizing and buffering properties.
Morpholine (1,4-Oxazinane) derivatives can be employed as octane enhancers in gasoline formulations.

In the printing industry, Morpholine (1,4-Oxazinane) is used in the preparation of certain solutions and inks.
Morpholine (1,4-Oxazinane) -based compounds can be used in waterborne coatings to enhance their performance.
Morpholine (1,4-Oxazinane) can be found in some tobacco products as an additive.

Morpholine (1,4-Oxazinane) is used in anti-corrosion paint formulations to protect metal surfaces.
In metal processing, Morpholine (1,4-Oxazinane) can be employed in pickling solutions to remove oxides and scales from metal surfaces.
Morpholine (1,4-Oxazinane) derivatives can serve as catalysts in hydroformylation reactions in the production of aldehydes.

In some wood preservation treatments, Morpholine (1,4-Oxazinane) can be included to protect against decay and insects.
Morpholine (1,4-Oxazinane) is used in the production of certain synthetic resins.
Morpholine (1,4-Oxazinane) dissolved in water neutralizes acids in exothermic reactions to form salts plus water.

Morpholine (1,4-Oxazinane) undergoes most chemical reactions typical for other secondary amines, though the presence of the ether oxygen withdraws electron density from the nitrogen, rendering it less nucleophilic (and less basic) than structurally similar secondary amines such as piperidine.
Morpholine (1,4-Oxazinane) forms a stable chloramine.
Colorless Liquid Morpholine (1,4-Oxazinane) Chemical has extensive application in water treatment plants.

This hygroscopic liquid chemical easily dilutes in water and most of organic solvents.
But it does not dissolve in alkaline liquid content.
This Morpholine (1,4-Oxazinane) has a distinctive smell that resembles the odor of ammonia.

Morpholine (1,4-Oxazinane) has a broad scope of applications.
Morpholine (1,4-Oxazinane) serves as an effective antioxidant, a chemical intermediate, gloss, and wax emulsifier in different industries.

Morpholine (1,4-Oxazinane) also serves as a polymerization prevention factor and as a paper preservative.
This liquid Morpholine (1,4-Oxazinane) is accessible in pure form.

Production method Of Morpholine (1,4-Oxazinane) :
Morpholine (1,4-Oxazinane) could be produced by diethanolamine dehydration cyclization derived from sulfuric acid.
Add diethanolamine to the water reaction pot and drop sulfuric acid in the temperature of 60 ℃, then when the temperature heat at 185-195 ℃, incubate it for 30min.
Cool it to under 60℃ and drop sodium hydroxide solution to pH = 11.

The next steeps are cooling, filtering, filtrating distillation, collecting the following fractions below 130℃.
The content of spermine is suppose to reach more than 99.5%. The method is easy to obtain raw materials, so it has become the main method of producing morpholine in the world.
Morpholine (1,4-Oxazinane) also could be produced in the catalytic reaction between dioxane and ammonia gas.

The preparation method is that we could get Morpholine from the presence of sulfuric acid dehydration cyclization diethanolamine In the presence of sulfuric acid ; then add diethanolamine into the reaction kettle and add H2SO4 at a temperature of below 6 °C, then heat it to 185-195 °C for 30 minutes, cool to 60 °C.
Drop NaOH solution to pH = 11, and the last two steeps is cooling and filtrating.

Morpholine (1,4-Oxazinane) could be collected from the fraction below 130 °C.
The method is easy to obtain raw materials, thus it is the main method of producing morpholine around the world.

Uses:
Morpholine (1,4-Oxazinane) also can be alkylated, and it also could come up a ketone reaction or Willgerodt reaction with ethylene oxide.
Morpholine (1,4-Oxazinane) can also be used as a component in agricultural fungicides and microbial removal.
Morpholine (1,4-Oxazinane) is one of the most widely used chemical compounds in various industries.

That is why many industries are looking for high-quality Morpholine (1,4-Oxazinane) .
In research and industry, Morpholine (1,4-Oxazinane) is used as a solvent for chemical reactions due to its low cost and high polarity.
Morpholine (1,4-Oxazinane) is used in the production of inks as a stabilizer and pH regulator.

Morpholine (1,4-Oxazinane) applied in electroplating processes, where it serves as a buffering agent.
Found in some cosmetic formulations for its humectant properties, helping to retain moisture.
Morpholine (1,4-Oxazinane) is used for the analysis of reagents and resins, wax, casein, shellac and a variety of solvents solvent.

Morpholine (1,4-Oxazinane) s used as corrosion inhibitors, insecticides, antiseptics, intermediate for rubber-processing chemicals; corrosion inhibitors; waxes and polishes; optical brighteners.
Morpholine (1,4-Oxazinane) reacts readily with fatty acids, forming soaps used in the formulation of self-polishing waxes and polishes and in coatings for the food industry.

Morpholine (1,4-Oxazinane) and TV-ethyl morpholine are used as catalysts in the manufacture of polyurethane foams.
Morpholine (1,4-Oxazinane) derivatives are utilized in pharmaceutical applications, as bactericides, fungicides, and herbicides, and as separating agents for oils.
Morpholine (1,4-Oxazinane) is used as a chemical emulsifier in the process of waxing fruit.

Naturally, fruits make waxes to protect against insects and fungal contamination, but this can be lost as the fruit is cleaned.
Morpholine (1,4-Oxazinane) is used in the leather industry as a dyeing assistant.
Morpholine (1,4-Oxazinane) is added to cooling and antifreeze fluids in some applications due to its ability to inhibit corrosion.

Morpholine (1,4-Oxazinane) can be involved in processes related to the desulfurization of gasoline.
Morpholine (1,4-Oxazinane) is the main raw materials of accelerator NOBS.
For analysis reagents and resins, wax, shellac and other solvents, used in the production of sodium sulfate.

Morpholine (1,4-Oxazinane) is Mainly used for the production of rubber vulcanization accelerator, but also for surfactant, textile auxiliaries, pharmaceuticals, pesticide synthesis.
Morpholine (1,4-Oxazinane) also used as a catalyst for polymerization of butadiene, corrosion inhibitors, optical bleach, the goods are dyes, resins, wax, early glue, casein and other solvents.
At present, the total production of morpholine in the world is 3-4 million t/a.

Morpholine (1,4-Oxazinane) salts are also widely used.
Found in the formulation of adhesives and sealants in industries like construction.
Morpholine (1,4-Oxazinane) is used in heat transfer fluids due to its thermal stability and low freezing point.

Employed in metal cleaning processes, particularly for removing rust and scale from metal surfaces.
Morpholine (1,4-Oxazinane) is used in the textile industry for dyeing and printing processes.
Morpholine (1,4-Oxazinane) applied in processes related to desulfurization, gas scrubbing, and as a scavenger for hydrogen sulfide.

Morpholine (1,4-Oxazinane) is used in certain formulations of paints and coatings as a stabilizer and pH regulator.
Found in the manufacture of certain photographic chemicals.
Morpholine (1,4-Oxazinane) is used in cooling water treatment to control corrosion and scale formation.

Morpholine (1,4-Oxazinane) and its derivatives serve as intermediates in the synthesis of pharmaceuticals.
Included in gasoline formulations to improve combustion efficiency and reduce vapor pressure.
Morpholine (1,4-Oxazinane) is used in wood preservation treatments to protect against decay and insects.

Morpholine (1,4-Oxazinane) added to certain antifreeze formulations to inhibit corrosion.
Morpholine (1,4-Oxazinane) is used as a humectant in cosmetics to retain moisture.
Morpholine (1,4-Oxazinane) is added to deicing fluids to enhance their performance.

Morpholine (1,4-Oxazinane) derivatives can be involved in the synthesis of certain fertilizers.
Morpholine (1,4-Oxazinane) is commonly used to generate enamines.
Morpholine (1,4-Oxazinane) is widely used in organic synthesis.

For example, Morpholine (1,4-Oxazinane) is a building block in the preparation of the antibiotic linezolid, the anticancer agent gefitinib (Iressa) and the analgesic dextromoramide.
Morpholine (1,4-Oxazinane) salts like morpholine hydrochloride (10024-89-2) are the organic synthesis of intermediates.
A small amount of new wax is applied to replace Morpholine (1,4-Oxazinane) .

Morpholine (1,4-Oxazinane) is used as an emulsifier and solubility aid for shellac, which is used as a wax for fruit coating.
The European Union has forbidden the use of morpholine in fruit coating.
Morpholine (1,4-Oxazinane) has been used as a reference standard for the identification of the analyte in water by gas chromatography-mass spectrometry (GC-MS).

Morpholine (1,4-Oxazinane) may be used as a reference standard for the determination of the analyte in fruit-based soft drinks, in natural waters and in vegetables by liquid chromatography-mass spectrometry (LC-MS) and in drugs by GC-MS.
Morpholine (1,4-Oxazinane) is widely used as a neutralizing amine to prevent carbonic acid corrosion in steam boiler systems.

Morpholine (1,4-Oxazinane) evaporates with the vapor in the system, and when the vapor becomes liquid, it liquefies with it, thus protecting the lines.
Morpholine (1,4-Oxazinane) vapors can prevent corrosion of silver and other metals, as well as obscuring their surfaces by acids such as sulfur dioxide and hydrogen sulfide.

Morpholine (1,4-Oxazinane) is made by dehydrating ethanolamines. Its main use is as a rubber accelerator in manufacturing tires.
This process requires high temperature (300°F) and pressure, which increase the hazards.
Morpholine (1,4-Oxazinane) is also used as a boiler water additive, brightener for detergents, and corrosion inhibitor, in the preservation of book paper, in waxes and polishes, and in organic synthesis.

Morpholine (1,4-Oxazinane) used as the raw materials for rubber accelerator and fluorescent whitening agent.
Morpholine (1,4-Oxazinane) is the intermediates of fungicide dimethomorph and flumorpholine and organophosphate insecticide phosalphos.
Morpholine (1,4-Oxazinane) fatty acid salt can be used as the coating agent of fruits or vegetables epidermal coating agent, and it could inhibit the base respiration and prevent the epidermis from evaporation of water and epidermal atrophy.

Morpholine (1,4-Oxazinane) derivatives can be involved in the synthesis of certain fertilizers.
Morpholine (1,4-Oxazinane) may be used as an additive in coolant formulations for specific applications.
In natural gas storage, Morpholine (1,4-Oxazinane) can be employed to prevent corrosion in storage tanks and pipelines.

Morpholine (1,4-Oxazinane) derivatives can be used in certain polymerization processes for cross-linking polymers.
Morpholine (1,4-Oxazinane) derivatives can be employed as additives in gasoline to control engine knock and improve fuel performance.
Morpholine (1,4-Oxazinane) derivatives act as catalysts in hydroformylation reactions, a process used in the production of aldehydes.

Morpholine (1,4-Oxazinane) can be part of aqueous cleaning solutions due to its solubility in water and ability to function as a stabilizer.
Morpholine (1,4-Oxazinane) derivatives are utilized in the synthesis of certain agricultural chemicals, including herbicides and pesticides.
Morpholine (1,4-Oxazinane) derivatives are investigated for their antifungal properties and potential applications in antifungal formulations.

Morpholine (1,4-Oxazinane) is used as an additive in detergent formulations for its stabilizing and buffering properties.
Morpholine (1,4-Oxazinane) is used in the printing industry for the preparation of solutions and inks.
Morpholine (1,4-Oxazinane) added to gasoline formulations to reduce vapor pressure and control emissions.

Morpholine (1,4-Oxazinane) is used as a curing agent for epoxy resins, contributing to the formation of solid and durable materials.
Morpholine (1,4-Oxazinane) derivatives may be used in the production of materials for photovoltaic devices.
Morpholine (1,4-Oxazinane) derivatives can be employed as octane enhancers in gasoline formulations.

Morpholine (1,4-Oxazinane) derivatives are used in biomedical research for potential pharmacological activities.
Morpholine (1,4-Oxazinane) is used in the production of polyurethane foams, where it can serve as a stabilizer and contribute to the foam's properties.
Morpholine (1,4-Oxazinane) is used in the paper and pulp industry as an additive in the pulping process.

Morpholine (1,4-Oxazinane) derivatives may be used as softeners in the textile industry.
Employed in metal pickling processes to remove oxides and scales from metal surfaces.
Other derivatives are utilized in the textile and printing industry as adjuvants, whitening agents, stabilizers, ink eradicators, and paper conditioners.

Morpholine (1,4-Oxazinane) , also known as Diethylenimide Oxide, is an organic chemical compound used in organic synthesis.
Morpholine (1,4-Oxazinane) could produce salt after reacting with inorganic acid, and it also could produce salt or amide after reacting with organic acid.
Morpholine (1,4-Oxazinane) derivatives can function as oxidation stabilizers in gasoline formulations.

Morpholine (1,4-Oxazinane) is used as an auxiliary agent in textile printing processes.
Morpholine (1,4-Oxazinane) is employed in the electronics industry for various applications, including the production of electronic chemicals.
Morpholine (1,4-Oxazinane) is a common additive, in parts per million concentrations, for pH adjustment in both fossil fuel and nuclear power plant steam systems.

Morpholine (1,4-Oxazinane) is used because its volatility is about the same as water, so once it is added to the water, its concentration becomes distributed rather evenly in both the water and steam phases.
Morpholine (1,4-Oxazinane) is pH-adjusting qualities then become distributed throughout the steam plant to provide corrosion protection.
Morpholine (1,4-Oxazinane) is often used in conjunction with low concentrations of hydrazine or ammonia to provide a comprehensive all-volatile treatment chemistry for corrosion protection for the steam systems of such plants.

Morpholine (1,4-Oxazinane) decomposes reasonably slowly in the absence of oxygen at the high temperatures and pressures in these steam systems.
Morpholine (1,4-Oxazinane) is generally considered an additive and is used for a variety of purposes.
Morpholine (1,4-Oxazinane) is often used as a corrosion inhibitor in steam boiler systems and water cooling systems to prevent corrosion of metal components.

Morpholine (1,4-Oxazinane) is employed in the natural gas industry for the removal of acidic components like hydrogen sulfide and carbon dioxide from natural gas streams.
Morpholine (1,4-Oxazinane) serves as a solvent in different industrial processes, including the extraction of natural gas and the purification of pharmaceuticals.

Morpholine (1,4-Oxazinane) is used as a pH regulator in water treatment processes and various industrial applications.
Morpholine (1,4-Oxazinane) is utilized in the production of rubber accelerators, curing agents, and as a component in certain polymerization processes.

Safety Information:
Morpholine (1,4-Oxazinane) is important to prevent its release into the environment, as it can be toxic to aquatic organisms and may have adverse effects on ecosystems.
Morpholine (1,4-Oxazinane) itself is not highly flammable, it should be stored away from sources of ignition.
Fire safety measures should be in place, and firefighting personnel should be aware of the chemical's properties in case of a fire.

Morpholine (1,4-Oxazinane) can cause irritation to the skin and eyes upon direct contact.
Adequate ventilation should be maintained in areas where the compound is handled, and respiratory protection may be necessary in situations with high concentrations of vapors.
Some individuals may develop sensitization to morpholine after repeated exposure, leading to allergic reactions.

Precautions, such as using protective clothing, can help minimize the risk of sensitization.
Morpholine (1,4-Oxazinane) is important to use appropriate personal protective equipment (PPE), such as gloves and goggles, to minimize the risk of skin and eye exposure.
Morpholine (1,4-Oxazinane) vapors may cause respiratory irritation.

Morpholine (1,4-Oxazinane) technical grade is classified as harmful if swallowed.
Ingestion can lead to adverse health effects, and the severity of these effects depends on factors such as the amount ingested and individual susceptibility.
Morpholine (1,4-Oxazinane) may have environmental implications.

MORPHOLINE (110-91-8)
Morpholine (110-91-8), also known as 1, 4-oxazepine and diethylenimine oxide, is a kind of colorless alkaline oily liquid.
Morpholine (110-91-8) smells of ammonia and has hygroscopicity.
Morpholine (110-91-8) could evaporate with water vapor and miscible with water.

CAS: 110-91-8
MF: C4H9NO
MW: 87.12
EINECS: 203-815-1

Synonyms
1,4-Oxazinan;1,4-oxazine,tetrahydro-;2H-1,4-Oxazine, tetrahydro-;4H-1,4-Oxazine, tetrahydro-;BASF 238;basf238;Diethylenimide oxide;diethylenimideoxide;Diethylene Oximide; Diethylene Imidoxide; Diethylenimide Oxide; Diethyleneimide Oxide; Tetrahydro-1, 4-Isoxazine; P-Isoxazine, Tetrahydro-; Caswell No. 584; Tetrahydro-P-Isoxazine; Morpholine (Substance)
;MORPHOLINE;110-91-8;1-Oxa-4-azacyclohexane;Diethylene oximide;Tetrahydro-1,4-oxazine;Diethylenimide oxide;Diethyleneimide oxide;Diethylene imidoxide;Drewamine;Tetrahydro-2H-1,4-oxazine;Tetrahydro-p-oxazine;p-Isoxazine, tetrahydro-;morpholin;Tetrahydro-1,4-isoxazine;BASF 238;Caswell No. 584;2H-1,4-Oxazine, tetrahydro-;4H-1,4-Oxazine, tetrahydro-;138048-80-3;NSC 9376;Tetrahydro-p-isoxazine;CCRIS 2482;HSDB 102;EINECS 203-815-1;UNII-8B2ZCK305O;EPA Pesticide Chemical Code 054701;BRN 0102549
;8B2ZCK305O;DTXSID2025688;CHEBI:34856;AI3-01231;NSC-9376;MFCD00005972;C4H9NO;Tetrahydro-4H-1-4-oxazine;DTXCID305688;EC 203-815-1;4-27-00-00015 (Beilstein Handbook Reference);MORPHOLINE (IARC);MORPHOLINE [IARC];MORPHOLINE-2,2,3,3,5,5,6,6-D8;tetrahydro-14-iso-xazine;1,4-oxazinane
;CAS-110-91-8;MORPHOLINE,REAG;MORPHOLINE, PRACT;UN2054;morphline;Morpholine; Molsidomine Imp. E (EP); Molsidomine Impurity E;morpho line;morpholine-;6LR;Morpholine (BASF);4H-1, tetrahydro-;MORPHOLINE [MI];Morpholine [UN2054] [Flammable liquid];MORPHOLINE [FCC];DIEYTHYLENE OXIMIDE;MORPHOLINE [HSDB];MORPHOLINE [INCI];Morpholine on Rasta Resin;WLN: T6M DOTJ;NCIMech_000154;Tetrahydro-1, 4-isoxazine;NCIOpen2_007748;Oprea1_317540;Tetryhydro-2H-1,4-oxazine;Tetrahydro-4H-1,4-Oxazine;61791-40-0;BIDD:ER0297;Morpholine, analytical standard;CHEMBL276518;NSC9376;AMY22834;BCP24054;STR00194;Tox21_202450;Tox21_303240;TETRAHYDRO-2H-1, 4-OXAZINE;AKOS000118829;Morpholine, ACS reagent, >=99.0%;Morpholine, ReagentPlus(R), >=99%;DB13669;NA 2054;UN 2054;USEPA/OPP Pesticide Code: 054701;NCGC00249227-01;NCGC00256942-01;NCGC00259999-01;Morpholine, p.a., ACS reagent, 99.0%;Morpholine [UN2054] [Flammable liquid];M0465;NS00010190;EN300-18064;Morpholine purified by distillation from glass;Morpholine, purified by redistillation, >=99.5%;Q410243;1-Oxa-4-azacyclohexane;Tetrahydro-2H-1,4-oxazine;J-522715;F2190-0339;InChI=1/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H;ScavengePore(TM) phenethyl morpholine, macroporous, 40-70 mesh, extent of labeling: 0.7-1.5 mmol/g loading;StratoSpheres(TM) PL-MPH resin, 50-100 mesh, extent of labeling: 3.0-4.0 mmol/g loading, 1 % cross-linked

Morpholine (110-91-8) is Soluble in acetone, benzene, ether, pentane, methanol, ethanol, carbon tetrachloride, propylene glycol and other organic solvents.
Morpholine (110-91-8) could form an explosive mixture with air and the explosion limit is 1.8% to 15.2% (volume fraction).
Morpholine (110-91-8) is a secondary amine, and at the same time it has the property of inorganic acid and organic acid, so that it can generate salt and amide.
Morpholine (110-91-8) contains secondary amine groups and it has all the typical reaction characteristics of the secondary amine groups.
Morpholine (110-91-8) can react with inorganic acid to form a salt, and also can react with organic acid to form salt or amide.
Morpholine (110-91-8) can carry out alkylation reactions and it also carry out ketone reaction or Willgerodt reaction with ethylene oxide.

Because of the unique chemical properties of Morpholine (110-91-8), it has become one of the important petrochemical products with important commercial application.
Morpholine (110-91-8) can be applied to produce rubber vulcanization accelerators such as NOBS, DTOS and MDS.
And Morpholine (110-91-8) is also applied to produce anti-corrosives, anti-corrosion agents, detergents, detergents, analgesics, local anesthetics, sedatives, respiratory and vascular stimulants, surfactants, optical bleach, fruit preservatives, and textile dyeing auxiliaries.
Morpholine (110-91-8) also has a wide range of applications in the field of rubber, pharmaceuticals, pesticides, dyes, coatings and other industries.
In medication Morpholine (110-91-8) could be applied in the production of morpholine guanidine, virus Ling, ibuprofen, cough must, naproxen, dichloroaniline, sodium phenylacetate and other important drugs.

Morpholine (110-91-8) is noteworthy that new polymer monomer acrylic morpholine has obtained a rapid development in recent years.
Acrylic acid Morpholine (110-91-8) could be produced from the reaction between acrylic acid and morpholine.
And acrylic acid Morpholine (110-91-8) is a kind of water-soluble monomer, and it is still water-soluble after the polymerization.
So Morpholine (110-91-8) could be applied for the modification of aqueous polymers.
Besides, acrylic Morpholine (110-91-8) is widely used as a reactive diluent for UV curable resins.
With the deepening of applied research, many new specific uses have been developed and Morpholine (110-91-8) becomes polymer monomer with rapid development.
Morpholine is a colorless liquid with a weakammonia or fish-like odor.
The odor threshold is 0.01 ppm.
Molecular weight = 87.14; Specific gravity (H2O:1) 51.007; Boiling point = 128.9℃; Freezing/Meltingpoint 5 25℃; Vapor pressure 5 6 mmHg at 20℃; Flashpoint 5 37℃.
Autoignition temperature 5 310℃.
Explosivelimits: LEL 5 1.4%; UEL 5 11.2%.

Hazard Identification(based on NFPA-704 M Rating System):Health 3,Flammability ,Reactivity 0.
Soluble in water.
Morpholine (110-91-8) is an organic heteromonocyclic compound whose six-membered ring contains four carbon atoms and one nitrogen atom and one oxygen atom that lies opposite to each other; the parent compound of the morpholine family.
Morpholine (110-91-8) is a saturated organic heteromonocyclic parent and a member of morpholines.
Morpholine (110-91-8) is a conjugate base of a morpholinium.
Morpholine (110-91-8) is an organic chemical compound having the chemical formula O(CH2CH2)2NH.
This heterocycle features both amine and ether functional groups.
Because of the amine, Morpholine (110-91-8) is a base; its conjugate acid is called morpholinium.
For example, treating morpholine with hydrochloric acid makes the salt morpholinium chloride. Morpholine (110-91-8) is a colorless liquid with a weak, ammonia- or fish-like odor.
The naming of Morpholine (110-91-8) is attributed to Ludwig Knorr, who incorrectly believed it to be part of the structure of morphine.
Morpholine (110-91-8), a pharmaceutical-grade compound, is known for its versatility in application and usage.
Primarily, Morpholine (110-91-8) serves as a solvent and catalyst integral to chemical reactions, garnering acclaim within the sphere of pharmaceutical syntheses.
The chemical formula C4H9NO and a molecular weight of 87.12 g/mol underscore precision in dosages and reactions.

Morpholine (110-91-8) Chemical Properties
Melting point: -7--5 °C (lit.)
Boiling point: 126.0-130.0 °C 129 °C (lit.)
Density: 0.996 g/mL at 25 °C (lit.)
Vapor density: 3 (vs air)
Vapor pressure: 31 mm Hg ( 38 °C)
Refractive index: n20/D 1.454(lit.)
Fp: 96 °F
Storage temp.: Store below +30°C.
Solubility water: miscible
Form: Liquid
Pka: 8.33(at 25℃)
Color: APHA: ≤15
Specific Gravity: 0.996
Odor: Characteristic amine-like odor
PH: 11.2 (H2O)(undiluted)
Explosive limit 1.4-15.2%(V)
Water Solubility: MISCIBLE
FreezingPoint: -4.9℃
Sensitive: Hygroscopic
Merck: 14,6277
BRN: 102549
Dielectric constant: 7.3(25℃)
Exposure limits: TLV-TWA 20 ppm (~70 mg/m3) (ACGIH, MSHA, and OSHA); STEL skin 30 ppm (ACGIH); IDLH 8000 ppm.
Stability: Stable. Flammable. Incompatible with strong oxidizing agents, strong acids, acid chlorides, acid anhydrides. Hygroscopic.
InChIKey: YNAVUWVOSKDBBP-UHFFFAOYSA-N
LogP: -0.860
CAS DataBase Reference: 110-91-8(CAS DataBase Reference)
NIST Chemistry Reference: Morpholine (110-91-8)(110-91-8)
IARC: 3 (Vol. 47, 71) 1999
EPA Substance Registry System: Morpholine (110-91-8) (110-91-8)

Morpholine (110-91-8) is colorless water-absorbing oily liquid and it smells ammonia.
Morpholine (110-91-8) is soluble in water and methanol, ethanol, benzene, acetone, ether, ethylene glycol and other commonly used solvents.
Morpholine (110-91-8) is a colorless to yellow liquid with a weak ammonia or fish-like odor.
The odor threshold is 0.01 ppm.
The reactivity of morpholine is mainly due to its secondary amine group.
Morpholine (110-91-8) readily undergoes organic condensations, alkylations, and arylations, resulting in the formation of various N-substituted morpholine compounds.
Ethers are relatively chemically inert, hence the oxygen is of relatively little consequence except as a member of the heterocyclic ring.

Physical properties
Colorless, mobile, oily, hygroscopic, flammable liquid with a weak ammonia-like odor.
Experimentally determined detection and recognition odor threshold concentrations were 40 μg/m3 (11 ppbv) and 25 μg/m3 (70 ppbv), respectively.
Forms explosive vapors at temperatures >35 °C.

Uses
For medicine, Morpholine (110-91-8) used as the raw materials for rubber accelerator and fluorescent whitening agent.
Morpholine (110-91-8) is the intermediates of fungicide dimethomorph and flumorpholine and organophosphate insecticide phosalphos.
Morpholine (110-91-8) is Mainly used for the production of rubber vulcanization accelerator, but also for surfactant, textile auxiliaries, pharmaceuticals, pesticide synthesis.
Morpholine (110-91-8) also used as a catalyst for polymerization of butadiene, corrosion inhibitors, optical bleach, the goods are dyes, resins, wax, early glue, casein and other solvents.
At present, the total production of Morpholine (110-91-8) in the world is 3-4 million t/a.
Morpholine salts are also widely used.

Morpholine (110-91-8) salts like morpholine hydrochloride (10024-89-2) are the organic synthesis of intermediates.
Morpholine (110-91-8) fatty acid salt can be used as the coating agent of fruits or vegetables epidermal coating agent, and it could inhibit the base respiration and prevent the epidermis from evaporation of water and epidermal atrophy.
Morpholine (110-91-8) is the main raw materials of accelerator NOBS. for analysis reagents and resins, wax, shellac and other solvents, used in the production of sodium sulfate.
Water glass and ultramarine.
Morpholine (110-91-8) is used for the analysis of reagents and resins, wax, casein, shellac and a variety of solvents solvent.
Morpholine (110-91-8) could produce salt after reacting with inorganic acid, and it also could produce salt or amide after reacting with organic acid.
Morpholine (110-91-8) also can be alkylated, and it also could come up a ketone reaction or Willgerodt reaction with ethylene oxide.

Morpholine (110-91-8) is made by dehydrating ethanolamines.
Morpholine (110-91-8)'s main use is as a rubber accelerator in manufacturing tires.
This process requires high temperature (300°F) and pressure, which increase the hazards.
Morpholine (110-91-8) is also used as a boiler water additive, brightener for detergents, and corrosion inhibitor, in the preservation of book paper, in waxes and polishes, and in organic synthesis.
Solvent for resins, waxes, casein, dyes; Morpholine (110-91-8) compounds used as corrosion inhibitors, insecticides, antiseptics, intermediate for rubber-processing chemicals; corrosion inhibitors; waxes and polishes; optical brighteners
Rubber accelerator, solvent, additive to boilerwater, waxes and polishes, optical brightener fordetergents, corrosion inhibitor, preservation of bookpaper, organic intermediate (catalyst, antioxidants,pharmaceuticals, bactericides, etc.).

Morpholine (110-91-8) is mainly used in the production of rubber vulcanization accelerators, and also used in the synthesis of surfactants, textile printing and dyeing auxiliaries, medicines and pesticides.
Morpholine (110-91-8) is also used as a catalyst for the polymerization of cis-butadiene, a corrosion inhibitor, and an optical bleach.
Morpholine (110-91-8) is also a solvent for dyes, resins, waxes, early gums, casein, and so on.
The salts of morpholine are also widely used.
Morpholine (110-91-8) is an intermediate of organic synthesis.
Morpholine (110-91-8) fatty acid salt can be used as a coating agent for the skin of fruits or melons and vegetables, and can appropriately inhibit the respiration of the base and preventthe evaporation of water and the shrinkage of epidermis.

Industrial uses
The total industrial consumption of Morpholine (110-91-8) is 11,000 metric tons/year.
The largest usage for Morpholine (110-91-8) (33%) is in the rubber industry as an intermediate in the production of delayed-action accelerators for the polymerization of rubber, as stabilizers against heat-aging effects, and as bloom inhibitors in butyl rubber vulcanization.
A second large proportion (25%) of morpholine production is used as an inhibitor to combat carbonic acid corrosion in condensate return lines of steam boiler systems.
Morpholine (110-91-8) is an intermediate in the manufacture of optical brighteners utilized by the soap and detergent industry.
Morpholine (110-91-8) reacts readily with fatty acids, forming soaps used in the formulation of self-polishing waxes and polishes and in coatings for the food industry.
N-methyl morpholine and TV-ethyl Morpholine (110-91-8) are used as catalysts in the manufacture of polyurethane foams.
Morpholine (110-91-8) derivatives are utilized in pharmaceutical applications, as bactericides, fungicides, and herbicides, and as separating agents for oils.
Other derivatives are utilized in the textile and printing industry as adjuvants, whitening agents, stabilizers, ink eradicators, and paper conditioners.

Metal Corrosion Inhibitors
As a kind of metal corrosion inhibitor, Morpholine (110-91-8) is mainly applied for the anti-corrosion of iron, copper, zinc, lead and other metals.
Morpholine (110-91-8) remains at its starting stage in China, but outside the country, a considerable proportion of Morpholine (110-91-8) are used as a kind of anti-rust agent for metal gas to prevent the metal corrosion caused by atmosphere and it has been widely used in the field of mechanical instruments, automobiles, medical equipment and others.
The metal atmospheric rust inhibitor used earlier such as dicyclohexylamine nitrite and cyclohexylamine do harm to the human body and they are more environmentally toxic.
Instead, Morpholine (110-91-8) as a metal gas-liquid corrosion inhibitor, it has the advantages of low toxicity, so the foreground is prosperous.

Rubber Vulcanization Accelerator
Before 1990's, in Europe, the United States, Japan and other developed areas, the consumption of rubber vulcanization accelerator accounted for more than 50% of the total demand for morpholine.
At present, more than 30% consumption of rubber vulcanization accelerator is used for NOBS.
In recent years, the toxicity issue of the harmful nitrosamines in the accelerator which produced during rubber processing is driving more attention internationally.
A number of restrictive laws and regulations are introduced all around the world. For example, in Germany as early as 1982, the law about the regulations issued nitrosamine content control was established.
The United States, Japan, France, the United Kingdom actively developed new vulcanization accelerator which don’t produce nitrosamine, and they have stopped using nitrosamine which will produce vulcanization accelerator.

Therefore, the consumption of Morpholine (110-91-8) in foreign countries has decreased with banning of the accelerator NOBS year by year.
But China has joined the WTO, due to a large number of foreign enter and high requirement about additives localization, Morpholine (110-91-8) requires more environmental protection in China's rubber vulcanization accelerator.
Using non-toxic promoter and replacing NOBS becomes the general trend.
China's demand for NOBS is significantly reduced in recent years.
China will no longer use basic decomposition of nitrosamine secondary amine accelerator.
As the main substitute of NOBS, NS (N-tert-butyl-2-benzothiazole sulfonamide), which does not produce nitrosamines, has a large production capacity.
In 2005, the output was 14,000 tons and Morpholine (110-91-8) is 10.1%, of the total amount.
So there was good development momentum.

Quantitative Analysis
Get 4 parts of methanol solution with 0.1% of bromocresol green and 1 part of 0.1% aqueous solution with 0.1% of methyl red sodium salt.
Mix them and put aside to use as a mixed indicator later.
Get 50ml water in 250ml flask, add 0.4ml mixed indicator, drop 0.1moI/L hydrochloric acid, and wait for the color to turn green.
Accurately weighs the sample 1.4~1.6g, add the flask and mix it.
Use 0.5mol/L hydrochloric acid titration and wait for the color to turn green.
Per ml, 0.5mol/L hydrochloric acid is equivalent to 43.56mg C4H9NO.

Production method
(1) Morpholine (110-91-8) could be produced by diethanolamine dehydration cyclization derived from sulfuric acid.
Add diethanolamine to the water reaction pot and drop sulfuric acid in the temperature of 60 ℃, then when the temperature heat at 185-195 ℃, incubate it for 30min.
Cool Morpholine (110-91-8) to under 60℃ and drop sodium hydroxide solution to pH = 11.
The next steeps are cooling, filtering, filtrating distillation, collecting the following fractions below 130℃.
The content of spermine is suppose to reach more than 99.5%.
The method is easy to obtain raw materials, so Morpholine (110-91-8) has become the main method of producing morpholine in the world.
Morpholine (110-91-8) also could be produced in the catalytic reaction between dioxane and ammonia gas.

(2) The preparation method is that we could get Morpholine (110-91-8) from the presence of sulfuric acid dehydration cyclization diethanolamine In the presence of sulfuric acid ; then add diethanolamine into the reaction kettle and add H2SO4 at a temperature of below 6 °C, then heat it to 185-195 °C for 30 minutes, cool to 60 °C.
Drop NaOH solution to pH = 11, and the last two steeps is cooling and filtrating. Morpholine could be collected from the fraction below 130 °C.
We can also get morpholine from the reaction between diethylene glycol and ammonia in the presence of catalyst and pressure.
The method is easy to obtain raw materials, thus Morpholine (110-91-8) is the main method of producing morpholine around the world.

Morpholine (110-91-8) is produced by reacting diethylene glycol, ammonia, and a small amount of hydrogen over a hydrogenation catalyst at 150-400°C and 30-400 atmospheres with the morpholine being recovered by fractional distillation.
Various byproducts include 2-(2-aminoethoxy)ethanol and Af-alkylmorpholines.

Reactivity Profile
Morpholine (110-91-8) dissolved in water neutralizes acids in exothermic reactions to form salts plus water.
May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
May cause toxic effects if inhaled or ingested/swallowed.
Contact with substance may cause severe burns to skin and eyes.
Fire will produce irritating, corrosive and/or toxic gases.
Vapors may cause dizziness or suffocation.
Runoff from fire control or dilution water may cause pollution.
Morpholine (110-91-8) is readily absorbed through the skin; it causes nasal irritation when inhaled, with coughing, bronchial irritation, and pulmonary edema at increasingly higher concentrations.
Upon ingestion, Morpholine (110-91-8) causes hemorrhage in the gastrointestinal tract, with possible diarrhea; liver and kidney damage may occur if sufficient amounts are ingested or inhaled.
Morpholine (110-91-8) itself is not a carcinogen on the basis of available data.
MORPHOLINE (C4H9NO)

Morpholine is a heterocyclic organic compound with the molecular formula C4H9NO.
Morpholine (C4H9NO) is a cyclic amine that contains both oxygen and nitrogen in its five-membered ring structure
Morpholine (C4H9NO) is a heterocyclic organic compound with a distinctive five-membered ring structure.

CAS Number: 110-91-8
EC Number: 203-815-1

Piperazinone, Tetrahydro-1,4-oxazine, Diethyleneimide, Morpholinium, Tetrahydrooxazine, 1,4-oxazine, Morpholinic Acid, 1,4-Oxazinane, Diethyleneimide, Morpholin, Tetrahydro-1,4-oxazine, Oxazinane, tetrahydro-1,4-, 1-Oxa-4-azacyclohexane, UNII-CCG5I79U9R, Tetrahydro-4-oxazine, Morpholinium, 1,4-Oxazinane, Tetramethyleneimide, Diethylene Oxide, 1,4-Dioxinane, Diethylene Imide, Oxazinane, Morpholinum, Piperazinone, Diethylene Oxide, 1,4-Dioxinane, Diethylene Imide, Oxazinane, Morpholinum, Piperazinone, Diethylene Oxide, 1,4-Dioxinane, Diethylene Imide, Oxazinane, Morpholinum, Piperazinone, Diethylene Oxide, 1,4-Dioxinane, Diethylene Imide, Oxazinane, Morpholinum, Piperazinone, Diethylene Oxide, 1,4-Dioxinane, Diethylene Imide, Oxazinane, Morpholinum, Piperazinone, Diethylene Oxide, 1,4-Dioxinane, Diethylene Imide, Oxazinane, Morpholinum, Piperazinone, Diethylene Oxide, 1,4-Dioxinane, Diethylene Imide, Oxazinane, Morpholinum, Piperazinone, Diethylene Oxide, 1,4-Dioxinane, Diethylene Imide, Oxazinane, Morpholinum, Piperazinone, Diethylene Oxide, 1,4-Dioxinane, Diethylene Imide, Oxazinane



APPLICATIONS


Morpholine (C4H9NO) is commonly used as a solvent in various chemical processes, thanks to its excellent solubility in water and organic solvents.
Morpholine (C4H9NO) plays a key role in the pharmaceutical industry, serving as an important intermediate in the synthesis of drugs.

In the field of corrosion inhibition, morpholine is utilized to protect metals in cooling systems from corrosion.
Morpholine (C4H9NO) finds application as a stabilizing agent in the production of rubber and polymers, contributing to the quality and durability of the final products.
Morpholine (C4H9NO) acts as a catalyst in certain chemical reactions, enhancing the efficiency of the reaction process.
Morpholine (C4H9NO) is employed in the production of surfactants, contributing to the formulation of detergents and cleaning products.
Morpholine (C4H9NO) is used as a raw material in the manufacturing of rubber accelerators, crucial for the rubber industry.

Morpholine (C4H9NO) is a valuable component in the synthesis of various agrochemicals and pesticides used in agriculture.
Morpholine (C4H9NO) serves as an important reagent in the synthesis of specialty chemicals, including pharmaceuticals, dyes, and coatings.
In the oil and gas industry, morpholine is employed to neutralize acidic components and prevent corrosion in refining processes.

Morpholine (C4H9NO) acts as a complexing agent in metal-catalyzed reactions, influencing the selectivity and efficiency of these reactions.
Morpholine (C4H9NO) is utilized as a scavenger in gas treatment processes to remove undesirable impurities such as hydrogen sulfide.

Morpholine (C4H9NO) finds application in water treatment to control pH levels and prevent corrosion in water systems.
Morpholine is used as a component in hydraulic fluids, helping to maintain the stability and performance of the fluids.

In the textile industry, morpholine is employed as a leveling agent in dyeing processes to ensure uniform coloration.
It plays a role in the synthesis of antioxidants, contributing to the stability and longevity of certain materials.

Morpholine is applied in the production of adhesives, sealants, and coatings, enhancing their performance characteristics.
In the manufacturing of cleaning agents, morpholine is used to formulate products with effective and controlled properties.
Morpholine (C4H9NO) is employed in the production of specialty chemicals used in the electronics and semiconductor industries.

Morpholine is utilized in the formulation of brake fluids, contributing to their stability and performance in automotive systems.
Morpholine (C4H9NO) serves as an effective buffering agent in various chemical processes, helping to maintain pH levels.
In the production of specialty polymers, morpholine contributes to the desired properties of the final polymer products.

Morpholine (C4H9NO) is used in the synthesis of pharmaceutical intermediates, aiding in the efficient production of medicines.
Morpholine (C4H9NO) finds application in gas sweetening processes, helping to remove unwanted sulfur compounds from natural gas.
Morpholine (C4H9NO) is employed in research laboratories as a versatile reagent in organic synthesis and chemical analysis.

Morpholine (C4H9NO) is utilized in the production of heat transfer fluids, enhancing their thermal stability and efficiency in various industrial processes.
In the field of paper and pulp production, morpholine is applied as a corrosion inhibitor to protect equipment from acidic substances.
Morpholine (C4H9NO) serves as a key ingredient in the formulation of cutting fluids used in metalworking processes to improve lubrication and cooling.

Morpholine is employed in the manufacturing of color developers for thermal paper, contributing to the development of images.
In the construction industry, morpholine is used as an additive in cement and concrete formulations to improve workability and reduce water demand.
Morpholine (C4H9NO) finds application in the synthesis of optical brighteners used in laundry detergents and textile processing.

Morpholine (C4H9NO) is used in the development of certain photography chemicals, contributing to the production of photographic emulsions.
In the production of batteries, morpholine is applied as a stabilizer for electrolytes, enhancing the overall performance of the battery.
Morpholine (C4H9NO) acts as a neutralizing agent in the production of polyurethane foams, aiding in the control of acidity during the manufacturing process.
Morpholine (C4H9NO) is employed in gas scrubbing systems to remove acidic impurities, ensuring compliance with environmental regulations.
Morpholine (C4H9NO) is used as a corrosion inhibitor in liquid formulations for metal cleaning and pickling processes.
In the textile and dyeing industry, morpholine functions as a dye leveling agent, ensuring uniform coloration of fabrics.

Morpholine (C4H9NO) is applied in the synthesis of herbicides and fungicides used in crop protection and agriculture.
Morpholine (C4H9NO) serves as a processing aid in the production of plastics, improving the flow characteristics during molding and extrusion processes.
Morpholine (C4H9NO) is utilized in the formulation of inkjet printing inks to enhance stability and performance.
Morpholine (C4H9NO) is employed in the development of coolant formulations for heat transfer systems in industrial equipment.

In the manufacturing of rubber and latex products, morpholine is used to control pH and prevent coagulation during processing.
Morpholine (C4H9NO) plays a role in the production of specialty chemicals used in the leather industry for tanning processes.
Morpholine (C4H9NO) is applied in the synthesis of pharmaceuticals, contributing to the creation of various therapeutic agents.

In the petrochemical industry, it is used as an additive in certain refinery processes to improve product quality.
Morpholine (C4H9NO) finds application in the production of plasticizers, enhancing the flexibility of plastics.
Morpholine (C4H9NO) is employed in the synthesis of corrosion-resistant coatings for metals and alloys.

Morpholine (C4H9NO) is utilized in the manufacturing of water-based paints and coatings for improved dispersion and stability.
In the formulation of household cleaning products, it functions as a stabilizing agent for certain formulations.
Morpholine (C4H9NO) is applied in the development of specialty chemicals used in the electronics industry for semiconductor manufacturing.

Morpholine (C4H9NO) is employed in the production of fuel additives, contributing to the stability and performance of fuels.
Morpholine (C4H9NO) plays a role in the formulation of metalworking fluids, enhancing lubrication and cooling during machining processes.
In the synthesis of pharmaceuticals, morpholine is used as a building block for the creation of diverse drug compounds.
Morpholine (C4H9NO) serves as a corrosion inhibitor in the treatment of industrial water systems, preventing metal degradation.

Morpholine (C4H9NO) is utilized in the development of specialty chemicals for use in the electronics industry, including semiconductor fabrication.
Morpholine (C4H9NO) finds application in the synthesis of herbicides and plant growth regulators for agricultural purposes.
In the rubber industry, it is used in the production of rubber accelerators to enhance the curing process.

Morpholine (C4H9NO) is applied in the formulation of brake fluids, ensuring the stability and performance of automotive braking systems.
Morpholine (C4H9NO) plays a role in the synthesis of optical brighteners, enhancing the whiteness and brightness of textiles.

In the creation of dyestuffs, morpholine is used to improve the solubility and color characteristics of dyes.
Morpholine (C4H9NO) is employed in the formulation of metal cleaning agents, enhancing the efficiency of cleaning processes.

Morpholine (C4H9NO) is used in the production of adhesives and sealants to improve the performance and stability of the final products.
Morpholine (C4H9NO) serves as a neutralizing agent in the manufacturing of polyurethane foams, contributing to their properties.

In the paper and pulp industry, it is applied as a corrosion inhibitor to protect equipment from acidic conditions.
Morpholine (C4H9NO) is utilized in the synthesis of color developers for thermal imaging and printing applications.
Morpholine (C4H9NO) finds application in the production of pharmaceutical intermediates, aiding in the efficient synthesis of medicines.
Morpholine (C4H9NO) is used in the formulation of inkjet inks to improve the stability and performance of printing.

In the oil and gas industry, it is employed in gas sweetening processes to remove sulfur compounds from natural gas.
Morpholine (C4H9NO) serves as a processing aid in the manufacturing of plastics, improving their molding characteristics.
Morpholine (C4H9NO) is utilized in the formulation of hydraulic fluids to enhance the stability and performance of the fluids.

Morpholine finds application in the production of coolant formulations for industrial heat transfer systems.
In the textile industry, it functions as a leveling agent in dyeing processes to ensure uniform coloration.
Morpholine (C4H9NO) is applied in the formulation of cutting fluids for metalworking, improving lubrication and cooling.

Morpholine (C4H9NO) plays a role in the development of specialty polymers, contributing to their unique properties.
Morpholine (C4H9NO) is employed in the synthesis of battery electrolytes, acting as a stabilizer for improved battery performance.



DESCRIPTION


Morpholine is a heterocyclic organic compound with the molecular formula C4H9NO.
Morpholine (C4H9NO) is a cyclic amine that contains both oxygen and nitrogen in its five-membered ring structure
Morpholine (C4H9NO) is a heterocyclic organic compound with a distinctive five-membered ring structure.

Morpholine (C4H9NO) has a faint, amine-like odor and is highly miscible with water.
Morpholine (C4H9NO) exhibits unique chemical properties due to the presence of both oxygen and nitrogen in its ring.
Morpholine (C4H9NO) is commonly used as a solvent for various chemicals, owing to its excellent solubility.
With a molecular formula of C4H9NO, morpholine consists of four carbon atoms, nine hydrogen atoms, one nitrogen atom, and one oxygen atom.

Morpholine (C4H9NO) is known for its versatile applications, ranging from industrial processes to pharmaceutical synthesis.
Morpholine (C4H9NO) is often used as a corrosion inhibitor in cooling systems to protect metals from degradation.
Morpholine (C4H9NO) is utilized in the production of certain drugs, acting as a crucial intermediate in pharmaceutical manufacturing.

As a cyclic amine, morpholine imparts specific properties to the substances it is incorporated into.
Morpholine (C4H9NO) is a clear liquid that can be easily handled and transported in laboratory and industrial settings.
Morpholine (C4H9NO) is widely employed as a stabilizing agent in the production of various chemical and polymer products.

Due to its heterocyclic nature, morpholine has a role in enhancing the reactivity of certain chemical reactions.
Its ability to form complexes with metals makes morpholine valuable in coordination chemistry.
In addition to its chemical applications, morpholine finds use in the agricultural sector for pest control.

The amine-like odor of morpholine is distinctive but generally faint, making it tolerable in controlled environments.
Morpholine (C4H9NO) is a key component in the synthesis of certain rubber accelerators used in the rubber industry.

Morpholine (C4H9NO)'s miscibility with water makes it suitable for formulations where water solubility is crucial.
Morpholine (C4H9NO) is used in the production of surfactants, enhancing the properties of cleaning and detergent products.

Its ring structure contributes to the stabilization of reaction intermediates in various chemical processes.
Morpholine (C4H9NO) has a boiling point of approximately 129 degrees Celsius, making it suitable for various industrial applications.

Morpholine (C4H9NO) is often handled with appropriate safety measures due to its potential health and safety considerations.
Morpholine (C4H9NO)'s use in cooling systems helps prevent corrosion, scaling, and the growth of microorganisms.
Morpholine (C4H9NO) is crucial to follow proper storage and handling protocols for morpholine to ensure its stability and purity.

The versatile nature of morpholine makes it a valuable component in the synthesis of diverse chemical compounds.
Morpholine (C4H9NO)'s significance extends across multiple industries, showcasing its adaptability and utility in various applications.



PROPERTIES


Chemical Formula: C4H9NO
Molecular Weight: 87.12 g/mol
Appearance: Clear, colorless liquid
Odor: Faint, amine-like odor
Melting Point: -3.6 °C (25.5 °F)
Boiling Point: 128.9 °C (264.02 °F)
Density: 0.999 g/cm³ at 20 °C
Solubility: Highly soluble in water and miscible with many organic solvents
pH (1% solution): Approximately 7 (neutral)
Refractive Index: 1.453
Flash Point: 34 °C (93.2 °F)
Autoignition Temperature: Not readily available
Vapor Pressure: 1.2 mmHg at 20 °C
Viscosity: 1.084 mPa·s at 20 °C
Flammability: Flammable liquid
Corrosivity: Mildly corrosive to metals under certain conditions
Hygroscopicity: Absorbs moisture from the air
Ionization Constant (pKa): 8.41
Hazardous Polymerization: Will not occur
Stability: Stable under normal conditions
Boiling Range: Approximately 127-130 °C
Vapor Density: 3 (Air = 1)
Partition Coefficient (Log P): -0.67
Critical Temperature: Not readily available
Critical Pressure: Not readily available



FIRST AID


Inhalation:

Move the affected person to fresh air.
Allow for rest and keep the individual in a comfortable position.
Seek medical attention if respiratory irritation persists or if symptoms worsen.


Skin Contact:

In case of skin contact, promptly remove contaminated clothing.
Wash the affected area with plenty of soap and water for at least 15 minutes.
Seek medical attention if irritation, redness, or other symptoms develop.


Eye Contact:

In case of contact with eyes, flush eyes with lukewarm water for at least 15 minutes, lifting upper and lower eyelids.
Seek medical attention if irritation persists or if there is any evidence of injury.


Ingestion:

If morpholine is accidentally ingested, do not induce vomiting.
Rinse the mouth thoroughly and drink plenty of water.
Seek immediate medical attention or contact a poison control center.


General Advice:

If someone shows signs of irritation or an allergic reaction after exposure to morpholine, remove the person from the source of exposure.
Provide comfort and reassurance.
If symptoms persist or if there is uncertainty about the exposure, seek medical advice promptly.



HANDLING AND STORAGE


Handling Conditions:

Personal Protection:
Wear appropriate personal protective equipment (PPE), including chemical-resistant gloves, safety goggles, and protective clothing.
Use respiratory protection if ventilation is inadequate or if exposure limits are exceeded.

Ventilation:
Work in a well-ventilated area, or use local exhaust ventilation to control airborne concentrations.

Avoidance of Contact:
Avoid direct skin contact and inhalation of vapors.
Use appropriate handling equipment and tools to minimize direct contact with the chemical.

Hygiene Practices:
Wash hands thoroughly after handling morpholine.
Do not eat, drink, or smoke while handling the chemical.

Preventive Measures:
Implement good industrial hygiene practices to minimize the risk of exposure.
Provide eye wash stations and safety showers in areas where the substance is handled.


Storage Conditions:

Storage Location:
Store morpholine in a cool, dry, and well-ventilated area.

Temperature Control:
Keep the storage temperature within the specified range provided by the manufacturer.

Container Type:
Use containers made of materials compatible with morpholine. Consult the SDS for guidance.

Protection from Elements:
Protect the substance from direct sunlight and sources of heat.

Separation from Incompatibles:
Store morpholine away from incompatible substances.
Check the SDS for information on substances that should be avoided.

Handling of Large Quantities:
If handling large quantities, use appropriate storage facilities with containment measures to prevent spills and leaks.

Labeling:
Ensure that storage containers are clearly labeled with the product name, hazard symbols, and other relevant information.

Security Measures:
Implement appropriate security measures to prevent unauthorized access to the storage area.
MORPHOLINE (CAS NO: 110-91-8)
DESCRIPTION:

Morpholine (CAS NO: 110-91-8) appears as a colorless liquid with a fishlike odor.
Flash point of Morpholine (CAS NO: 110-91-8) is 100 °F.
Morpholine (CAS NO: 110-91-8) is Corrosive to tissue.

CAS number :110-91-8
EC number 203-815-1
Hill Formula : C₄H₉NO
Molar Mass: 87.12 g/mol


SYNONYMS OF MORPHOLINE (CAS NO: 110-91-8):
1,4-oxazine,tetrahydro-;2H-1,4-Oxazine, tetrahydro-;4H-1,4-Oxazine, tetrahydro-;BASF 238;basf238;Diethylenimide oxide;diethylenimideoxide;tetrahydro-4h-4-oxazine,Morpholine;Diethylene imidoxide;Diethylene oximide;Diethylenimide oxide;p-Isoxazine,tetrahydro-;1-Oxa-4-azacyclohexane;2H-1,4-Oxazine,tetrahydro-;4H-1,4-Oxazine,tetrahydro-;Tetrahydro-p-oxazine;Tetrahydro-1,4-oxazine;Tetrahydro-2H-1,4-oxazine;BASF 238;Drewamine;NSC 9376;88542-81-8;96122-95-1;99108-56-2;147366-31-2;854893-20-2;1357848-50-0,morpholine,morpholine hydrochloride,morpholine hydroiodide,morpholine phosphate,morpholine phosphate (3:1),morpholine phosphonate (1:1),morpholine sulfite (1:1),MORPHOLINE,110-91-8,1-Oxa-4-azacyclohexane,Diethylene oximide,Tetrahydro-1,4-oxazine,Diethylenimide oxide,Diethyleneimide oxide,Diethylene imidoxide,Drewamine,Tetrahydro-2H-1,4-oxazine,Tetrahydro-p-oxazine,p-Isoxazine, tetrahydro-,morpholin,Tetrahydro-1,4-isoxazine,BASF 238,Caswell No. 584,138048-80-3,2H-1,4-Oxazine, tetrahydro-,4H-1,4-Oxazine, tetrahydro-,NSC 9376,Tetrahydro-p-isoxazine,CCRIS 2482,HSDB 102,EINECS 203-815-1,UNII-8B2ZCK305O,EPA Pesticide Chemical Code 054701,BRN 0102549,8B2ZCK305O,DTXSID2025688,CHEBI:34856,AI3-01231,NSC-9376,MFCD00005972,C4H9NO,Tetrahydro-4H-1-4-oxazine,DTXCID305688,EC 203-815-1,4-27-00-00015 (Beilstein Handbook Reference),MORPHOLINE (IARC),MORPHOLINE [IARC],tetrahydro-14-iso-xazine,1,4-oxazinane,CAS-110-91-8,MORPHOLINE,REAG,MORPHOLINE, PRACT,UN2054,morphline,Morpholine; Molsidomine Imp. E (EP); Molsidomine Impurity E,morpho line,morpholine-,6LR,Morpholine (BASF),4H-1, tetrahydro-,MORPHOLINE [MI],Morpholine [UN2054] [Flammable liquid],MORPHOLINE [FCC],DIEYTHYLENE OXIMIDE,MORPHOLINE [HSDB],Morpholine on Rasta Resin,WLN: T6M DOTJ,NCIMech_000154,Tetrahydro-1, 4-isoxazine,NCIOpen2_007748,Oprea1_317540,Tetryhydro-2H-1,4-oxazine,Tetrahydro-4H-1,4-Oxazine,61791-40-0,BIDD:ER0297,Morpholine, analytical standard,CHEMBL276518,NSC9376,AMY22834,BCP24054,STR00194,Tox21_202450,Tox21_303240,STL182843,TETRAHYDRO-2H-1, 4-OXAZINE,AKOS000118829,Morpholine, ACS reagent, >=99.0%,Morpholine, ReagentPlus(R), >=99%,DB13669,NA 2054,UN 2054,USEPA/OPP Pesticide Code: 054701,NCGC00249227-01,NCGC00256942-01,NCGC00259999-01,Morpholine, p.a., ACS reagent, 99.0%,DB-030063,Morpholine [UN2054] [Flammable liquid],M0465,NS00010190,EN300-18064,Morpholine purified by distillation from glass,Morpholine, purified by redistillation, >=99.5%,Q410243,1-Oxa-4-azacyclohexane; Tetrahydro-2H-1,4-oxazine,J-522715,1-Oxa-4-azacyclohexane ; Tetrahydro-2H-1,4-oxazine,F2190-0339,InChI=1/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H,ScavengePore(TM) phenethyl morpholine, macroporous, 40-70 mesh, extent of labeling: 0.7-1.5 mmol/g loading,StratoSpheres(TM) PL-MPH resin, 50-100 mesh, extent of labeling: 3.0-4.0 mmol/g loading, 1 % cross-linked

Morpholine (CAS NO: 110-91-8) is Less dense than water and soluble in water.
Vapors of Morpholine (CAS NO: 110-91-8) is heavier than air.
Morpholine (CAS NO: 110-91-8) is Used to make other chemicals, as a corrosion inhibitor, and in detergents.


Morpholine is an organic heteromonocyclic compound whose six-membered ring contains four carbon atoms and one nitrogen atom and one oxygen atom that lies opposite to each other; the parent compound of the morpholine family.
Morpholine (CAS NO: 110-91-8) has a role as a NMR chemical shift reference compound.

Morpholine (CAS NO: 110-91-8) is a saturated organic heteromonocyclic parent and a member of morpholines.
Morpholine (CAS NO: 110-91-8) is a conjugate base of a morpholinium.





Morpholine (CAS NO: 110-91-8) is an organic chemical compound having the chemical formula O(CH2CH2)2NH.
This heterocycle features both amine and ether functional groups.
Because of the amine, Morpholine (CAS NO: 110-91-8) is a base; its conjugate acid is called morpholinium.
For example, treating Morpholine (CAS NO: 110-91-8) with hydrochloric acid makes the salt morpholinium chloride.


Morpholine (CAS NO: 110-91-8) is used as an important building block mainly in
• rubber
• optical brighteners
• pharma
• agro industry
• solvent for the fibre industry
• other applications of Morpholine include, inter alia, water treatment



Morpholine (CAS: 110-91-8) is an organic chemical compound.
Its secondary amine function gives it the properties of a base.
This molecule is often produced industrially by the dehydration of diethanolamine (DEA) with sulfuric acid.

Morpholine ( CAS: 110-91-8) is a common pH adjustment additive, both in fossil fuels and in the steam systems of nuclear power plants, where it is employed to provide protection against corrosion

Morpholine (CAS: 110-91-8) is widely used in organic synthesis.
Morpholine (CAS NO: 110-91-8) is used, for example, in the preparation of the antibiotic Linezolid, the anticancer agent Gefinitib (Iressa) or the analgesic Dextromoramide (Palfium).


Morpholine (CAS NO: 110-91-8) is a common additive, in parts per million concentrations, for adjusting pH in fossil fuel and nuclear steam installations.
Morpholine (CAS NO: 110-91-8) can be soluble in water of any volume.
Morpholine (CAS NO: 110-91-8) is soluble in organic solvents like aromatic hydrocarbons, alcohol, ketone, ether and other organic solvents.

Morpholine (CAS NO: 110-91-8) is slightly soluble in mineral oil and aliphatic hydrocarbons.
Morpholine (CAS NO: 110-91-8) has slight toxicity.
Morpholine (CAS NO: 110-91-8) reacts with inorganic acid to generate salt, with organic acids to produce salt or acrylamide.

Morpholine (CAS NO: 110-91-8) can take alkylation reaction and Willgerodt reaction.
Morpholine (CAS NO: 110-91-8) can also react with epoxyethane and ketone and take Willgerodt reaction.


Morpholine is a chemical compound that belongs to the class of heteromonocyclic organic compounds.
Its chemical formula is C4H9NO and its CAS number is 110-91-8.
Morpholine is also known by several synonyms, including diethylene imidoxide, tetrahydro-1,4-oxazine, and N-methyl-1,4-oxazinanamine.


The appearance of morpholine is that of a clear, colorless liquid with a slight amine odor.
Morpholine (CAS NO: 110-91-8) is very soluble in water and ethanol and insoluble in ether.
The melting point of morpholine is -4 degrees and its boiling point is 129 degrees.

Morpholine (CAS NO: 110-91-8) is widely used in various industries and is known for its unique properties.
Morpholine (CAS NO: 110-91-8) is mainly used as a solvent, especially for dyes, resins, waxes and oils.
Morpholine (CAS NO: 110-91-8) is also used as a corrosion inhibitor for metal surfaces, as a rubber accelerator and as a catalyst in the production of rubber, plastics and pharmaceuticals.

Morpholine (CAS NO: 110-91-8) is commercially available in bottles or drums.
Its transportation and storage must be handled with care and in accordance with industry regulations.
Its manufacturing procedures involve the reaction of diethylene glycol with ammonia at high temperatures and pressures.

In conclusion, morpholine is a very useful chemical with a wide range of applications in various industries.
Its unique properties make it an essential component in the manufacturing processes of several products.
Although it is important to handle and transport it safely, the positive impact of morpholine in various industries should not be overlooked




APPLICATIONS OF MORPHOLINE (CAS NO: 110-91-8):

Morpholine is mainly used to make rubber accelerator (such as NOBS, OTOS and MDS), sulfurizing agent (such as DT-DM), cleaner, descaler, rust remover, anti-burning agent, antiseptic, surfactant, textile printing and dyeing agent, optical brightener, chemical bath, antioxidant, hydrolyzing agent, initiator, developer, fruit preservative, deodorizer, brightener and organic solvents.

Its applications are very wide.
Its application in fields such as medicine, pesticide, veterinary medicine, petroleum and coke aromatic hydrocarbon extraction have been continuously developed and applied.
Abroad, a large part of morpholine is used for anti-rust, descaling and cleaning of metals, especially for anti-rust and anti-corrosion under high temperature conditions.

In boiler maintenance areas, morpholine amount is also used as a descaling agent.
Due to its unique chemical characters, morpholine has become one of the most important fine petroleum chemicals and its applications are very wide.

Morpholine (CAS NO: 110-91-8) is Used in the production of various drugs such as rubber accelerators, synthetic virazole, ibuprofen, and ketamine.
Morpholine (CAS NO: 110-91-8) is also widely used in paints, pesticides, whitening agents, solvents, and other fields.
Morpholine (CAS NO: 110-91-8) can also be used to manufacture various intermediates such as N-methylmorpholine and N-ethylmorpholine










CHEMICAL AND PHYSICAL PROPERTIES OF MORPHOLINE (CAS NO: 110-91-8):
CAS number 110-91-8
EC index number 613-028-00-9
EC number 203-815-1
Hill Formula C₄H₉NO
Molar Mass 87.12 g/mol
HS Code 2934 99 11
Boiling point 129 °C (1013 hPa)
Density 1.000 g/cm3 (20 °C)
Explosion limit 1.4 - 15.2 %(V)
Flash point 32 °C
Ignition temperature 275 °C
Melting Point -7 - -5 °C
pH value 10.6 (5 g/l, H₂O, 20 °C) (undiluted)
Vapor pressure 9.33 hPa (20 °C)
Viscosity kinematic 2.2 mm2/s (20 °C)
Assay (GC, area%) ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C) 0.999 - 1.001
Water (K. F.) ≤ 0.30 %
Identity (IR) passes test
vapor pressure
11 hPa ( 20 °C)
Quality Level
200
Assay
≥99.0% (GC)
form
liquid
autoignition temp.
275 °C
potency
1900 mg/kg LD50, oral (Rat)
500 mg/kg LD50, skin (Rabbit)

expl. lim.
1.4-15.2 % (v/v)
pH
11 ( in H2O, undiluted)
kinematic viscosity
2.2 cSt(20 °C)
bp
129 °C/1013 hPa
mp
-5 °C
transition temp
flash point 32 °C
density
1.00 g/cm3 at 20 °C
storage temp.
2-30°C
InChI
1S/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H2
InChI key
YNAVUWVOSKDBBP-UHFFFAOYSA-N
Molecular Weight
87.12 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
XLogP3
-0.9
Computed by XLogP3 3.0 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
1
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
2
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
0
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
87.068413911 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
87.068413911 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
21.3Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
6
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
34.5
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
0
Computed by PubChem
Undefined Atom Stereocenter Count
0
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
1
Computed by PubChem
Compound Is Canonicalized
Yes

Morpholine

99.5% min

Boiling range

0℃,101.33KPa

5ml

126-130℃

95ml

Color Hazen (Pt-Co)

15 max
Moisture: 0.15% max
Density p20,g/cm3: 0.999-1.002
Impurity : 0.05% max
Melting point -7--5 °C (lit.)
Boiling point 126.0-130.0 °C 129 °C (lit.)
density 0.996 g/mL at 25 °C (lit.)
vapor density 3 (vs air)
vapor pressure 31 mm Hg ( 38 °C)
refractive index n20/D 1.454(lit.)
Fp 96 °F
storage temp. Store below +30°C.
solubility water: miscible
form Liquid
pka 8.33(at 25℃)
color APHA: ≤15
Specific Gravity 0.996
PH 11.2 (H2O)(undiluted)
Odor Characteristic amine-like odor
explosive limit 1.4-15.2%(V)
Water Solubility MISCIBLE
FreezingPoint -4.9℃
Sensitive Hygroscopic
Merck 14,6277
BRN 102549
Exposure limits TLV-TWA 20 ppm (~70 mg/m3) (ACGIH, MSHA, and OSHA); STEL skin 30 ppm (ACGIH); IDLH 8000 ppm.
Dielectric constant 7.3(25℃)
Stability: Stable. Flammable. Incompatible with strong oxidizing agents, strong acids, acid chlorides, acid anhydrides. Hygroscopic.
InChIKey YNAVUWVOSKDBBP-UHFFFAOYSA-N
LogP -0.860
CAS DataBase Reference 110-91-8(CAS DataBase Reference)
IARC 3 (Vol. 47, 71) 1999
NIST Chemistry Reference Morpholine(110-91-8)
EPA Substance Registry System Morpholine (110-91-8)
PSA:
21.26000
XLogP3:
-1.08
Appearance:
APHA: ≤15 Liquid
Density:
1.0007 g/cm3 @ Temp: 20 °C
Melting Point:
-4.9 °C
Boiling Point:
128.9 °C @ Press: 760 Torr
Flash Point:
96 °F
Refractive Index:
1.415
Water Solubility:
Micible with water.
Storage Conditions:
Store at R.T.
Vapor Pressure:
31 mm Hg ( 38 °C)
Vapor Density:
3 (vs air)
Toxicity:
Oral-rat LD50: 1050 mg/kg; Oral-Mouse LD50: 525 mg/kg
Flammability characteristics:
Flammable; burning produces toxic chloride gas
Explosive limit:
1.4-15.2%(V)
Odor:
Characteristic amine
PH:
Strong base
Appearance Light yellow to yellow liquid
Purity 98%(Min,GC)
Moisture 0.5%Max.
Melting Point −7-−5 ºC(lit.)
Boiling Point 129 ºC(lit.)
Flash Point 96 ºF
Application Intermediate in organicc synethese
Production Scale Up to kgs







SAFETY INFORMATION ABOUT MORPHOLINE (CAS NO: 110-91-8)
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.


MORPHOLINE TECHNICAL GRADE
Morpholine technical grade is a colorless, hygroscopic liquid free of suspended matter.
Morpholine technical gradeis fully miscible with water and almost all common organic solvents, and slightly soluble in aliphatic hydrocarbons.


CAS Number: 110-91-8
EC Number: 203-815-1
MDL Number: MFCD00005972
Molecular Formula: C4H9NO


Morpholine technical grade is a colorless, hygroscopic liquid free of suspended matter.
Morpholine technical gradeis fully miscible with water and almost all common organic solvents, and slightly soluble in aliphatic hydrocarbons.
Morpholine technical grade, also known as Diethylenimide Oxide, is an organic chemical compound used in organic synthesis.


Morpholine technical grade is an extremely versatile chemical with many important applications.
Morpholine technical grade appears as a colorless liquid with a fishlike odor.
Flash point of Morpholine technical grade is 100 °F.


Morpholine technical grade is less dense than water and soluble in water.
Morpholine technical-grade's vapors are heavier than air.
Morpholine technical grade is an organic heteromonocyclic compound whose six-membered ring contains four carbon atoms and one nitrogen atom and one oxygen atom that lies opposite to each other; the parent compound of the Morpholine technical grade family.


Morpholine technical grade is a saturated organic heteromonocyclic parent and a member of morpholines.
Morpholine technical grade is a conjugate base of a morpholinium.
Morpholine technical grade is one of the extremely versatile compounds broadly as a boiler corrosion inhibitor in steam boiler systems.


Morpholine technical grade is an organic amine used as boiler corrosion inhibitor.
Morpholine technical grade finds a variety of uses such as manufacturing of rubber accelerators, curing agents, cleaning agents, anti-rust agents, and surface-active agents.


Morpholine technical grade contains both amine and ether groups, used in a wide range of applications.
The amine group makes its base, Morpholine technical grade's conjugate acid is called morpholinium, which appears as a colourless liquid with a fishlike smell.


In boiler water treatment, Morpholine technical grade helps increase the pH of boiler feed water to protect the boiler against corrosion.
Morpholine technical grade acts as a base due to the presence of amine and its conjugate acid is known as morpholinium.
One gets the salt morpholinium chloride, if Morpholine technical grade is neutralized by hydrochloric acid.


Morpholine technical grade is an organic amine used as boiler corrosion inhibitor.
Morpholine technical grade acts as a base due to the presence of amine and its conjugate acid is known as morpholinium.
One gets the salt morpholinium chloride, if Morpholine technical grade is neutralized by hydrochloric acid.



USES and APPLICATIONS of MORPHOLINE TECHNICAL GRADE:
Morpholine technical grade is used as an intermediate in the manufacture of rubber chemicals and optical brighteners.
Morpholine technical grade is also used extensively as a corrosion inhibitor in steam boiler systems.
Morpholine technical grade is also used as organic synthetic building block and a laboratory solvent.


Morpholine technical grade is used a corrosion inhibitor, especially in steam boiler systems, an emulsifier for cosmetics, rubless waxes, and polishes, a separating agent for volatile amines, an intermediate in the manufacture of optical brighteners, an intermediate for textile lubricants, softening agents, adjuvants, whitening agents, sizing emulsifiers, rubber vulcanization accelerators, antioxidants, surface-active agents, plasticizers, viscosity improvers, insecticides, fumigants, herbicides, dyes, catalysts, bactericides, analgesics, anesthetics, and other physiologically active agents.


Morpholine technical grade is generally used as a chemical intermediate in corrosion inhibitors for steam boiler systems, but also has uses in pharmaceuticals, textiles, rubbers, catalysts, plasticizers, dyes, and agricultural and photographic chemicals.
Morpholine technical grade, Reagent, ACS is used as an industrial pH modifier and corrosion inhibitor.


As an ACS grade quality reagent, Morpholine technical grade's chemical specifications are the de facto standards for chemicals used in many high-purity applications and typically designate the highest quality chemical available for laboratory use.
Spectrum Chemical manufactured Reagent Morpholine technical grade products meet the toughest regulatory standards for quality and purity.


Colorless Liquid Morpholine technical grade Chemical has extensive application in water treatment plants.
This hygroscopic liquid chemical, Morpholine technical grade, easily dilutes in water and most of organic solvents.
But Morpholine technical grade does not dissolve in alkaline liquid content.


This organic chemical compound, Morpholine technical grade, has a distinctive smell that resembles the odor of ammonia.
Morpholine technical grade has a broad scope of applications.
Morpholine technical grade serves as an effective antioxidant, a chemical intermediate, gloss, and wax emulsifier in different industries.


Morpholine technical grade also serves as a polymerization prevention factor and as a paper preservative.
Morpholine technical grade is accessible in pure form.
Morpholine technical grade is used to make other chemicals, as a corrosion inhibitor, and in detergents.


Morpholine technical grade is an organic compound with amine and other functional groups that are used in the manufacture of rubber accelerators, curing agents, cleaning agents, anti-rust agents, and Surface-active agents.
Morpholine technical grade helps to increase the pH of boiler water to protect the boiler against corrosion.


Morpholine technical grade is used as an intermediate in the manufacture of rubber chemicals and optical brighteners.
Morpholine technical grade has also been used as a gelling agent in the preparation of alumina catalysts for the treatment of hydrocarbons.
Morpholine technical grade is available in the form of colorless liquid.


The key benefit of using Morpholine technical grade is that it can be used in all types, sizes, and pressure of boilers.
Morpholine technical grade, also called 1,4-oxyazocyclohexane, is a colorless, oily liquid with ammonia flavor at room temperature, which can be used as analytical reagent and resin, wax and shellac solvents.


Morpholine technical grade has characteristics of ether and amine compounds because the heterocyclic ring contains nitrogen and oxygen.
Compared to Morpholine technical grade, the oxygen in the N-heterocyclic ring is replaced by sulfur in the structure of thiomorphline.
Thiomorphline is often used as an important structural fragment in the design of new drugs due to its good biological activity.


The secondary amine groups of Morpholine technical grade and thiomorphline can react with ketone, ester and nitrile to form 1, 4-additive compound by Michael reaction.
The most important reaction of Morpholine technical grade and thiomorphline is the substitution reaction of secondary amine atoms with alcohols, compounds and complexes of acids.


Under the atmosphere of H2, Morpholine technical grade can react with primary or secondary alcohols to form a series of compound molasses derivatives with high conversion rate.
Morpholine technical grade and dihydric alcohol are able to produce morpholine alcohols and dimorpholine derivatives, which are also able to react with acids to obtain a series of ester drugs.


Morpholine technical grade is used as boiler inhibitor intermediate available in the form of a colourless liquid.
Morpholine technical grade is an additive used in PPM concentrations, pH adjustment in both fossil fuel and nuclear power plant steam systems
Having the same volatility as water, Morpholine technical grade is used as concentration becomes distributed rather evenly in both the water and steam phases


Morpholine technical grade's pH adjusting qualities are distributed throughout the steam plant to provide corrosion protection.
Morpholine technical grade finds a variety of uses such as manufacturing of rubber accelerators, curing agents, cleaning agents, anti-rust agents, and surface-active agents.


Morpholine technical grade contains both amine and ether groups, used in a wide range of applications.
The amine group makes its base, Morpholine technical grade's conjugate acid is called morpholinium, which appears as a colourless liquid with a fishlike smell.


In boiler water treatment, Morpholine technical grade helps increase the pH of boiler feed water to protect the boiler against corrosion.
Morpholine technical grade is used as boiler inhibitor intermediate available in the form of a colourless liquid.
Morpholine technical grade's pH adjusting qualities are distributed throughout the steam plant to provide corrosion protection.


Morpholine technical grade is an additive used in PPM concentrations, pH adjustment in both fossil fuel and nuclear power plant steam systems
Having the same volatility as water, Morpholine technical grade is used as concentration becomes distributed rather evenly in both the water and steam phases.


-Antioxidants and Stabilizers:
The complex formed by morpholine and ascorbic acid is served as a synergistic antioxidant for lipid.
N,N-Thiodimorpholine and N-tert-butyl morpholine can be used as antioxidants in lubricating oils.
The Morpholine technical grade salt of gallnut acid is a stabilizer of carotene and vitamin A and an antioxidant of glycerin.


-Rubber additives:
The major application of thiomorpholine derivatives is the production of rubber additives, in which 4, 4-dithiodimorpholine (DTDM) can be used as a vulcanization agent, and OTOS is also a typical kind of vulcanization promoter.


-Medicine:
In terms of medicine, Morpholine technical grade derivatives can be used as analgesics, local anesthetics, antispasmodic and other drugs.
Fominoben is a new antitussive agent.
Clinically, Morphocycline is used for the treatment of various serious infections caused by tetracycline-sensitive bacteria, and also for the diagnosis of lung cancer.
In addition, bimolane is involved with the treatment of psoriasis.


-Anti-scaling Agent uses of Morpholine technical grade:
Morpholine technical grade is widely used as corrosion inhibitor and scale inhibitor for steam boiler, and N-tert-butyl morpholine and morpholine sulfonate has a good corrosion resistance to oil storage tank and pipeline equipment.


-Anti-scorching Agent uses of Morpholine technical grade:
Morpholine technical grade produced by the condensation of morpholine subsulfonyl chloride and phthalimide is a kind of effective anticoke agent, which is a new product developed abroad in recent years.


-Metal Corrosion Inhibitor uses of Morpholine technical grade:
Some Morpholine technical grade derivatives are regard as anti-rust agents for metal products to prevent metal from being corroded by the atmosphere and have been widely used in the fields of mechanical vehicles, instruments and medical instruments, etc.
Morpholine technical grade has the advantage of low toxicity as a metal corrosion inhibitor and has a good development prospect.



HOW DOES MORPHOLINE TECHNICAL GRADE WORK?
Boilers are usually used in various industrial companies for their steam production capability.
Ensure that such boiler systems are correctly going on and they work at optimum efficiency.
To ensure an efficient process and quality steam creation capacity of the boiler system, the correct water condition must be maintained at all times.

Heat exchange, steam protection, and corrosion protection are all necessary for boiler water treatment.
The efficiency of any boiler depends upon Morpholine technical grade's capability of heat transfer.
In a boiler system, all the contact surfaces between the fireside and steam side are made up of metals or metal combinators as metals are good conductors of heat.

A large number of components can be dissolved in water as water is known as a universal solvent.
Now the water used here is mostly untreated such as river water, tap water, municipal bores, etc. which has dissolved oxygen.
Morpholine technical grade reacts with metal and forms metal oxide.

These oxides can occur in corrosive reactions and can degrade the metallic property of the boiler system.
Morpholine technical grade can be accomplished by dosing selected chemicals for boiler water treatment into the feed water.

The appropriate Boiler system will assist with keeping away from higher repair costs, poor quality of steam, and expensive maintenance fees because of scaling, consumption, and fouling of the heater and downstream apparatus.
Continuous accumulation of salts and when Morpholine technical grade exceeds the solvency results in the formation of scales.



CHEMICAL PROPERTIES OF MORPHOLINE TECHNICAL GRADE:
Liquid Morpholine Chemical Properties:
Morpholine technical grade is transparent and colorless, and it smells strongly of amines.
Due to its high water solubility, Morpholine technical grade may be used in a variety of watery applications.

The superior buffering capabilities of liquid morphine make Morpholine technical grade valuable for regulating pH and stabilizing solutions.
Various organic compounds, including medicines and agrochemicals, are often produced using Morpholine technical grade as a catalyst.
In industrial operations, Morpholine technical grade works as a corrosion inhibitor to prevent rust and metal deterioration.

Morpholine technical grade has good thermal stability as a result of its distinctive chemical structure, making it suited for high-temperature applications.
Due to its capacity to dissolve a variety of substances, Morpholine technical grade is also used as a solvent in the formation of coatings, dyes, and pigments.



WHAT ARE THE BENEFITS OF USING MORPHOLINE TECHNICAL GRADE AS A BOILER CORROSION INHIBITOR?
BENEFITS OF USING OF MORPHOLINE TECHNICAL GRADE:
*Prevents corrosion due to stress cracking
*Does not contribute to TDS
*Reduces blow-down requirement
*Compatible with other boiler water treatment chemicals
*Returns to the feed line with the condensate return raising the feed water pH
*Should Use Morpholine for Your Boilers



PHYSICAL and CHEMICAL PROPERTIES of MORPHOLINE TECHNICAL GRADE:
CAS No.: 110-91-8
Molecular Weight: 87.12
EC No.: 203-815-1
Melting Point -5 °C
Boiling Point 128.9±0.0 °C at 760 mmHg
Flash Point 35.6±0.0 °C
Molecular Formula C4H9NO
Molecular Weight 87.120
Density 0.9±0.1 g/cm3
Grade: Technical
Form: Liquid
Appearance: liquid
Auto Ignition Temperature: 255 °C (491 °F)
Boiling Point: 128 - 130 °C (262 - 266 °F)

Color: yellow, Clear, Colorless
Density: 1 g/cm3 @ 20 °C (68 °F)
Dynamic Viscosity: 2.23 mPa.s @ 20 °C (68 °F)
Flash Point: 32 °C (90 °F)
Lower Explosion Limit: 1.4 - 1.8 %(V)
Odor: ammoniacal
Partition Coefficient: Pow: 25 °C (77 °F)
log Pow: -2.55 @ 25 °C (77 °F)
pH: 10.1 - 11 @ 20 - 25 °C (68 - 77 °F)
Relative Density: 1.0007 @ 20 °C (68 °F) Reference Material: (water = 1)
Relative Vapor Density: 3 @ 20 °C (68 °F)
Solubility in Other Solvents: completely miscible
Solubility in Water: completely miscible
Upper Explosion Limit: 11.2 - 15.2 %(V)

Vapor Pressure: 7.5 mmHg @ 20 °C (68 °F)
Density: 0.9±0.1 g/cm3
Boiling Point: 128.9±0.0 °C at 760 mmHg
Melting Point: -5 °C
Molecular Formula: C4H9NO
Molecular Weight: 87.120
Flash Point: 35.6±0.0 °C
Exact Mass: 87.068413
PSA: 21.26000
LogP: -1.08
Vapour density: 3 (vs air)
Vapour Pressure: 10.4±0.2 mmHg at 25°C
Index of Refraction: 1.415
Storage condition: Store at R.T.
Stability: Stable.
Water Solubility: MISCIBLE
Freezing Point: -4.9℃

Molecular Formula / Molecular Weight: C4H9NO = 87.12
Physical State (20 deg.C): Liquid
Store Under Inert Gas: Store under inert gas
Condition to Avoid: Air Sensitive
CAS RN: 110-91-8
Reaxys Registry Number: 102549
PubChem Substance ID: 87572517
SDBS (AIST Spectral DB): 1330
Merck Index (14): 6277
MDL Number: MFCD00005972
Molecular Weight: 87.12 g/mol
XLogP3: -0.9
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2

Rotatable Bond Count: 0
Exact Mass: 87.068413911 g/mol
Monoisotopic Mass: 87.068413911 g/mol
Topological Polar Surface Area: 21.3Ų
Heavy Atom Count: 6
Formal Charge: 0
Complexity: 34.5
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes



FIRST AID MEASURES of MORPHOLINE TECHNICAL GRADE:
-After inhalation:
Fresh air.
Immediately call in physician.
-In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
-After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
-After swallowing:
Call a physician immediately.
Do not attempt to neutralise.



ACCIDENTAL RELEASE MEASURES of MORPHOLINE TECHNICAL GRADE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up carefully with liquid-absorbent material.
Dispose of properly.



FIRE FIGHTING MEASURES of MORPHOLINE TECHNICAL GRADE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of MORPHOLINE TECHNICAL GRADE:
-Control parameters:
*Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles.
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Viton
Minimum layer thickness: 0,7 mm
Break through time: 60 min
*Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of MORPHOLINE TECHNICAL GRADE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of MORPHOLINE TECHNICAL GRADE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).



SYNONYMS:
1,4-Oxazinan
EINECS 203-815-1
Morpholine
MORPHOLINE,ACS
1-Oxa-4-azacyclohexane
BASF 238
Drewamine
MORPHOLIN
Tetrahydro-1,4-oxazine
dihydro-1,4-oxazine
perhydro-1,4-oxazine
MFCD00005972
4-morpholin-4-ylsulfonyl benzenesulfonyl chloride
4-morpholine-4-sulfonyl benzene-1-sulfonyl chloride
4-morpholinosulfonyl benzene-1-sulfonyl chloride
4-morpholine-4-sulfonyl benzenesulfonyl chloride
4-morpholine-4-sulfonyl-benzenesulfonyl chloride
4-morpholine-4-sulfonyl phenylsulfonyl chloride
4-morpholine-4-sulfonyl-benzenesulfonylchloride
Diethylene imidoxide
Diethylene oximide
Tetrahydro-1,4-oxazine
Tetrahydro-p-oxazine.
MORPHOLINE
110-91-8
1-Oxa-4-azacyclohexane
Diethylene oximide
Tetrahydro-1,4-oxazine
Diethylenimide oxide
Diethyleneimide oxide
Diethylene imidoxide
Drewamine
Tetrahydro-2H-1,4-oxazine
Tetrahydro-p-oxazine
p-Isoxazine, tetrahydro-
morpholin
Tetrahydro-1,4-isoxazine
BASF 238
Caswell No. 584
2H-1,4-Oxazine, tetrahydro-
4H-1,4-Oxazine, tetrahydro-
138048-80-3
NSC 9376
Tetrahydro-p-isoxazine
CCRIS 2482
HSDB 102
EINECS 203-815-1
UNII-8B2ZCK305O
EPA Pesticide Chemical Code 054701
BRN 0102549
8B2ZCK305O
DTXSID2025688
CHEBI:34856
AI3-01231
NSC-9376
MFCD00005972
C4H9NO
Tetrahydro-4H-1-4-oxazine
DTXCID305688
EC 203-815-1
4-27-00-00015 (Beilstein Handbook Reference)
MORPHOLINE (IARC)
MORPHOLINE [IARC]
MORPHOLINE-2,2,3,3,5,5,6,6-D8
tetrahydro-14-iso-xazine
1,4-oxazinane
CAS-110-91-8
MORPHOLINE,REAG
MORPHOLINE, PRACT
UN2054
morphline
Morpholine
Molsidomine Imp. E (EP)
Molsidomine Impurity E
morpho line
morpholine-
6LR
Morpholine (BASF)
4H-1, tetrahydro-
MORPHOLINE [MI]
Morpholine [UN2054]
MORPHOLINE [FCC]
DIEYTHYLENE OXIMIDE
MORPHOLINE [HSDB]
MORPHOLINE [INCI]
Morpholine on Rasta Resin
WLN: T6M DOTJ
NCIMech_000154
Tetrahydro-1, 4-isoxazine
NCIOpen2_007748
Oprea1_317540
Tetryhydro-2H-1,4-oxazine
Tetrahydro-4H-1,4-Oxazine
BIDD:ER0297
Morpholine, analytical standard
CHEMBL276518
NSC9376
AMY22834
BCP24054
STR00194
Tox21_202450
Tox21_303240
TETRAHYDRO-2H-1, 4-OXAZINE
AKOS000118829
Morpholine, ACS reagent, >=99.0%
Morpholine, ReagentPlus(R), >=99%
DB13669
NA 2054
UN 2054
USEPA/OPP Pesticide Code: 054701
NCGC00249227-01
NCGC00256942-01
NCGC00259999-01
Morpholine, p.a., ACS reagent, 99.0%
Morpholine [UN2054]
FT-0628993
M0465
EN300-18064
Morpholine purified by distillation from glass
Morpholine, purified by redistillation, >=99.5%
Q410243
J-522715
F2190-0339
InChI=1/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H



MORPHOLINE TECHNICAL GRADE
Morpholine technical grade is an organic chemical compound having the chemical formula O(CH2CH2)2NH.
This heterocycle features both amine and ether functional groups.
Because of the amine, Morpholine technical grade is a base; its conjugate acid is called morpholinium.

CAS: 110-91-8
MF: C4H9NO
MW: 87.12
EINECS: 203-815-1

Synonyms
1,4-Oxazinan;1,4-oxazine,tetrahydro-;2H-1,4-Oxazine, tetrahydro-;4H-1,4-Oxazine, tetrahydro-;BASF 238;basf238;Diethylenimide oxide;diethylenimideoxide;MORPHOLINE;110-91-8;1-Oxa-4-azacyclohexane;Diethylene oximide;Tetrahydro-1,4-oxazine;Diethylenimide oxide;Diethyleneimide oxide;Diethylene imidoxide;Drewamine;Tetrahydro-2H-1,4-oxazine;Tetrahydro-p-oxazine;p-Isoxazine, tetrahydro-;morpholin;Tetrahydro-1,4-isoxazine;BASF 238;Caswell No. 584;2H-1,4-Oxazine, tetrahydro-;4H-1,4-Oxazine, tetrahydro-;138048-80-3;NSC 9376;Tetrahydro-p-isoxazine;CCRIS 2482;HSDB 102;EINECS 203-815-1;UNII-8B2ZCK305O
;EPA Pesticide Chemical Code 054701;BRN 0102549;8B2ZCK305O;DTXSID2025688;CHEBI:34856;AI3-01231;NSC-9376;MFCD00005972;C4H9NO;Tetrahydro-4H-1-4-oxazine;DTXCID305688;EC 203-815-1;4-27-00-00015 (Beilstein Handbook Reference);MORPHOLINE (IARC);MORPHOLINE [IARC];MORPHOLINE-2,2,3,3,5,5,6,6-D8;tetrahydro-14-iso-xazine;1,4-oxazinane;CAS-110-91-8;MORPHOLINE,REAG;MORPHOLINE, PRACT;UN2054;morphline;Morpholine; Molsidomine Imp. E (EP); Molsidomine Impurity E;morpho line;morpholine-;6LR;Morpholine (BASF);4H-1, tetrahydro-;MORPHOLINE [MI];Morpholine [UN2054] [Flammable liquid];MORPHOLINE [FCC];DIEYTHYLENE OXIMIDE;MORPHOLINE [HSDB];MORPHOLINE [INCI];Morpholine on Rasta Resin;WLN: T6M DOTJ;NCIMech_000154;Tetrahydro-1, 4-isoxazine;NCIOpen2_007748;Oprea1_317540;Tetryhydro-2H-1,4-oxazine;Tetrahydro-4H-1,4-Oxazine;61791-40-0;BIDD:ER0297;Morpholine, analytical standard;CHEMBL276518;NSC9376;AMY22834;BCP24054;STR00194;Tox21_202450;Tox21_303240;TETRAHYDRO-2H-1, 4-OXAZINE;AKOS000118829;Morpholine, ACS reagent, >=99.0%;Morpholine, ReagentPlus(R), >=99%;DB13669;NA 2054;UN 2054;USEPA/OPP Pesticide Code: 054701;NCGC00249227-01;NCGC00256942-01;NCGC00259999-01;Morpholine, p.a., ACS reagent, 99.0%;Morpholine [UN2054] [Flammable liquid];FT-0628993;M0465;NS00010190;EN300-18064;Morpholine purified by distillation from glass;Morpholine, purified by redistillation, >=99.5%;Q410243;J-522715;F2190-0339;InChI=1/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H;ScavengePore(TM) phenethyl morpholine, macroporous, 40-70 mesh, extent of labeling: 0.7-1.5 mmol/g loading;StratoSpheres(TM) PL-MPH resin, 50-100 mesh, extent of labeling: 3.0-4.0 mmol/g loading, 1 % cross-linked

For example, treating Morpholine technical grade with hydrochloric acid makes the salt morpholinium chloride.
Morpholine technical grade is a colorless liquid with a weak, ammonia- or fish-like odor.
The naming of Morpholine technical grade is attributed to Ludwig Knorr, who incorrectly believed it to be part of the structure of morphine.
Morpholine technical grade, also known as 1, 4-oxazepine and diethylenimine oxide, is a kind of colorless alkaline oily liquid.
Morpholine technical grade smells of ammonia and has hygroscopicity.
Morpholine could evaporate with water vapor and miscible with water.
Morpholine technical grade is Soluble in acetone, benzene, ether, pentane, methanol, ethanol, carbon tetrachloride, propylene glycol and other organic solvents.
Morpholine technical grade could form an explosive mixture with air and the explosion limit is 1.8% to 15.2% (volume fraction).

Morpholine technical grade is a secondary amine, and at the same time it has the property of inorganic acid and organic acid, so that it can generate salt and amide.
Morpholine technical grade contains secondary amine groups and it has all the typical reaction characteristics of the secondary amine groups.
Morpholine technical grade can react with inorganic acid to form a salt, and also can react with organic acid to form salt or amide.
Morpholine technical grade can carry out alkylation reactions and it also carry out ketone reaction or Willgerodt reaction with ethylene oxide.
Because of the unique chemical properties of morpholine, Morpholine technical grade has become one of the important petrochemical products with important commercial application.
Morpholine technical grade can be applied to produce rubber vulcanization accelerators such as NOBS, DTOS and MDS.
And Morpholine technical grade is also applied to produce anti-corrosives, anti-corrosion agents, detergents, detergents, analgesics, local anesthetics, sedatives, respiratory and vascular stimulants, surfactants, optical bleach, fruit preservatives, and textile dyeing auxiliaries.

Morpholine technical grade also has a wide range of applications in the field of rubber, pharmaceuticals, pesticides, dyes, coatings and other industries.
In medication Morpholine technical grade could be applied in the production of morpholine guanidine, virus Ling, ibuprofen, cough must, naproxen, dichloroaniline, sodium phenylacetate and other important drugs.
The two main production method of Morpholine technical grade are DEA method (diethanolamine method) and DEA method (diethylene glycol method)
Morpholine technical grade is noteworthy that new polymer monomer acrylic morpholine has obtained a rapid development in recent years.
Acrylic acid Morpholine technical grade could be produced from the reaction between acrylic acid and morpholine.
And acrylic acid Morpholine technical grade is a kind of water-soluble monomer, and it is still water-soluble after the polymerization.
So Morpholine technical grade could be applied for the modification of aqueous polymers.

Besides, Morpholine technical grade is widely used as a reactive diluent for UV curable resins.
With the deepening of applied research, many new specific uses have been developed and Morpholine technical grade becomes polymer monomer with rapid development.
Morpholine technical grade is an organic heteromonocyclic compound whose six-membered ring contains four carbon atoms and one nitrogen atom and one oxygen atom that lies opposite to each other; the parent compound of the morpholine family.
Morpholine technical grade is a saturated organic heteromonocyclic parent and a member of morpholines.
Morpholine technical grade is a conjugate base of a morpholinium.
Morpholine is incredibly common but a surprisingly little-known substance.
Morpholine technical grade has applications as diverse as cleaning, rubber production, construction, heating and cooling, personal care, agriculture, and so much more.

Morpholine technical grade Chemical Properties
Melting point: -7--5 °C (lit.)
Boiling point: 126.0-130.0 °C 129 °C (lit.)
Density: 0.996 g/mL at 25 °C (lit.)
Vapor density: 3 (vs air)
Vapor pressure: 31 mm Hg ( 38 °C)
Refractive index: n20/D 1.454(lit.)
Fp: 96 °F
Storage temp.: Store below +30°C.
Solubility water: miscible
Form: Liquid
pka: 8.33(at 25℃)
Color: APHA: ≤15
Specific Gravity: 0.996
Odor: Characteristic amine-like odor
PH: 11.2 (H2O)(undiluted)
Explosive limit: 1.4-15.2%(V)
Water Solubility: MISCIBLE
FreezingPoint: -4.9℃
Sensitive: Hygroscopic
Merck: 14,6277
BRN: 102549
Dielectric constant: 7.3(25℃)
Exposure limits TLV-TWA 20 ppm (~70 mg/m3) (ACGIH, MSHA, and OSHA); STEL skin 30 ppm (ACGIH); IDLH 8000 ppm.
Stability: Stable. Flammable. Incompatible with strong oxidizing agents, strong acids, acid chlorides, acid anhydrides. Hygroscopic.
InChIKey: YNAVUWVOSKDBBP-UHFFFAOYSA-N
LogP: -0.860
CAS DataBase Reference: 110-91-8(CAS DataBase Reference)
NIST Chemistry Reference: Morpholine(110-91-8)
IARC: 3 (Vol. 47, 71) 1999
EPA Substance Registry System: Morpholine technical grade (110-91-8)

Morpholine technical grade is colorless water-absorbing oily liquid and it smells ammonia.
Morpholine technical grade is soluble in water and methanol, ethanol, benzene, acetone, ether, ethylene glycol and other commonly used solvents.
Morpholine technical grade is a colorless to yellow liquid with a weak ammonia or fish-like odor.
The odor threshold is 0.01 ppm.
The reactivity of Morpholine technical grade is mainly due to its secondary amine group.
Morpholine technical grade readily undergoes organic condensations, alkylations, and arylations, resulting in the formation of various N-substituted morpholine compounds.
Ethers are relatively chemically inert, hence the oxygen is of relatively little consequence except as a member of the heterocyclic ring.
Colorless, mobile, oily, hygroscopic, flammable liquid with a weak ammonia-like odor. Experimentally determined detection and recognition odor threshold concentrations were 40 μg/m3 (11 ppbv) and 25 μg/m3 (70 ppbv), respectively.
Forms explosive vapors at temperatures >35 °C.

Uses
(1) For medicine, Morpholine technical grade used as the raw materials for rubber accelerator and fluorescent whitening agent.
(2) Morpholine technical grade is the intermediates of fungicide dimethomorph and flumorpholine and organophosphate insecticide phosalphos.
(3) Morpholine technical grade is Mainly used for the production of rubber vulcanization accelerator, but also for surfactant, textile auxiliaries, pharmaceuticals, pesticide synthesis.
(4) Morpholine technical grade also used as a catalyst for polymerization of butadiene, corrosion inhibitors, optical bleach, the goods are dyes, resins, wax, early glue, casein and other solvents.
At present, the total production of morpholine in the world is 3-4 million t/a.
(5) Morpholine technical grade like morpholine hydrochloride are the organic synthesis of intermediates.
Morpholine technical grade fatty acid salt can be used as the coating agent of fruits or vegetables epidermal coating agent, and it could inhibit the base respiration and prevent the epidermis from evaporation of water and epidermal atrophy.
(6) Morpholine technical grade is the main raw materials of accelerator NOBS. for analysis reagents and resins, wax, shellac and other solvents, used in the production of sodium sulfate.
(7) Morpholine technical grade is used for the analysis of reagents and resins, wax, casein, shellac and a variety of solvents solvent.
(8) Morpholine technical grade could produce salt after reacting with inorganic acid, and it also could produce salt or amide after reacting with organic acid.
Morpholine technical grade also can be alkylated, and it also could come up a ketone reaction or Willgerodt reaction with ethylene oxide.

Rubber accelerator, solvent, additive to boilerwater, waxes and polishes, optical brightener fordetergents, corrosion inhibitor, preservation of bookpaper, organic intermediate (catalyst, antioxidants,pharmaceuticals, bactericides, etc.).
Morpholine is made by dehydrating ethanolamines.
Morpholine technical grade's main use is as a rubber accelerator in manufacturing tires.
This process requires high temperature (300°F) and pressure, which increase the hazards.
Morpholine technical grade is also used as a boiler water additive, brightener for detergents, and corrosion inhibitor, in the preservation of book paper, in waxes and polishes, and in organic synthesis.

Industrial uses
The total industrial consumption of Morpholine technical grade is 11,000 metric tons/year.
The largest usage for Morpholine technical grade (33%) is in the rubber industry as an intermediate in the production of delayed-action accelerators for the polymerization of rubber, as stabilizers against heat-aging effects, and as bloom inhibitors in butyl rubber vulcanization.
A second large proportion (25%) of Morpholine technical grade is used as an inhibitor to combat carbonic acid corrosion in condensate return lines of steam boiler systems.
Morpholine technical grade is an intermediate in the manufacture of optical brighteners utilized by the soap and detergent industry.
Morpholine technical grade reacts readily with fatty acids, forming soaps used in the formulation of self-polishing waxes and polishes and in coatings for the food industry.
Morpholine technical grade and TV-ethyl morpholine are used as catalysts in the manufacture of polyurethane foams.
Morpholine technical grade derivatives are utilized in pharmaceutical applications, as bactericides, fungicides, and herbicides, and as separating agents for oils.
Other derivatives are utilized in the textile and printing industry as adjuvants, whitening agents, stabilizers, ink eradicators, and paper conditioners.

Metal Corrosion Inhibitors
As a kind of metal corrosion inhibitor, Morpholine technical grade is mainly applied for the anti-corrosion of iron, copper, zinc, lead and other metals.
Morpholine technical grade remains at its starting stage in China, but outside the country, a considerable proportion of Morpholine technical grade are used as a kind of anti-rust agent for metal gas to prevent the metal corrosion caused by atmosphere and it has been widely used in the field of mechanical instruments, automobiles, medical equipment and others.
The metal atmospheric rust inhibitor used earlier such as dicyclohexylamine nitrite and cyclohexylamine do harm to the human body and they are more environmentally toxic.
Instead, morpholine as a metal gas-liquid corrosion inhibitor, Morpholine technical grade has the advantages of low toxicity, so the foreground is prosperous.

Rubber Vulcanization Accelerator
Before 1990's, in Europe, the United States, Japan and other developed areas, the consumption of rubber vulcanization accelerator accounted for more than 50% of the total demand for Morpholine technical grade.
At present, more than 30% consumption of rubber vulcanization accelerator is used for NOBS.
In recent years, the toxicity issue of the harmful nitrosamines in the accelerator which produced during rubber processing is driving more attention internationally.
A number of restrictive laws and regulations are introduced all around the world.
For example, in Germany as early as 1982, the law about the regulations issued nitrosamine content control was established.
The United States, Japan, France, the United Kingdom actively developed new vulcanization accelerator which don’t produce nitrosamine, and they have stopped using nitrosamine which will produce vulcanization accelerator.
Therefore, the consumption of morpholine in foreign countries has decreased with banning of the accelerator NOBS year by year.
In China however, we have no corresponding regulations prohibited about banning accelerator NOBS. But China has joined the WTO, due to a large number of foreign enter and high requirement about additives localization, Morpholine technical grade requires more environmental protection in China's rubber vulcanization accelerator.
Using non-toxic promoter and replacing NOBS becomes the general trend.
China's demand for NOBS is significantly reduced in recent years.
China will no longer use basic decomposition of nitrosamine secondary amine accelerator.
As the main substitute of NOBS, NS (N-tert-butyl-2-benzothiazole sulfonamide), which does not produce nitrosamines, has a large production capacity.
In 2005, the output was 14,000 tons and Morpholine technical grade is 10.1%, of the total amount.
So there was good development momentum.

Production method
(1) Morpholine technical grade could be produced by diethanolamine dehydration cyclization derived from sulfuric acid.
Add diethanolamine to the water reaction pot and drop sulfuric acid in the temperature of 60 ℃, then when the temperature heat at 185-195 ℃, incubate it for 30min.
Cool Morpholine technical grade to under 60℃ and drop sodium hydroxide solution to pH = 11.
The next steeps are cooling, filtering, filtrating distillation, collecting the following fractions below 130℃.
The content of spermine is suppose to reach more than 99.5%.
The method is easy to obtain raw materials, so Morpholine technical grade has become the main method of producing morpholine in the world.
Morpholine technical grade also could be produced in the catalytic reaction between dioxane and ammonia gas.

(2) The preparation method is that we could get Morpholine technical grade from the presence of sulfuric acid dehydration cyclization diethanolamine In the presence of sulfuric acid ; then add diethanolamine into the reaction kettle and add H2SO4 at a temperature of below 6 °C, then heat it to 185-195 °C for 30 minutes, cool to 60 °C.
Drop NaOH solution to pH = 11, and the last two steeps is cooling and filtrating.
Morpholine technical grade could be collected from the fraction below 130 °C.
The method is easy to obtain raw materials, thus Morpholine technical grade is the main method of producing morpholine around the world.

Morpholine technical grade is produced by reacting diethylene glycol, ammonia, and a small amount of hydrogen over a hydrogenation catalyst at 150-400°C and 30-400 atmospheres with the morpholine being recovered by fractional distillation.
Various byproducts include 2-(2-aminoethoxy)ethanol and Af-alkylmorpholines.

Health Hazard
May cause toxic effects if inhaled or ingested/swallowed.
Contact with substance may cause severe burns to skin and eyes.
Fire will produce irritating, corrosive and/or toxic gases.
Vapors may cause dizziness or suffocation.
Runoff from fire control or dilution water may cause pollution.
Morpholine technical grade is readily absorbed through the skin; it causes nasal irritation when inhaled, with coughing, bronchial irritation, and pulmonary edema at increasingly higher concentrations.
Upon ingestion, Morpholine technical grade causes hemorrhage in the gastrointestinal tract, with possible diarrhea; liver and kidney damage may occur if sufficient amounts are ingested or inhaled.
Morpholine technical grade itself is not a carcinogen on the basis of available data.
MORPHOLINE TECHNICAL GRADE
Morpholine technical grade is a heterocyclic organic compound with the molecular formula C4H9NO.
Morpholine technical grade consists of a six-membered ring containing both nitrogen and oxygen atoms.
Morpholine technical grade is a colorless, amine-like liquid with a characteristic amine odor.

CAS Number: 110-91-8
Molecular Formula: C4H9NO
Molecular Weight: 87.12
EINECS Number: 203-815-1

In Morpholine technical grade, the term "technical grade" typically refers to a product that may not meet the high purity standards required for laboratory or pharmaceutical use but is suitable for various industrial applications.
Morpholine technical grade is often used in a range of industrial processes and applications due to its chemical properties.
Morpholine technical grade is a colorless, amine-like liquid with a characteristic odor.

Morpholine technical grade is an organic heteromonocyclic compound whose six-membered ring contains four carbon atoms and one nitrogen atom and one oxygen atom that lies opposite to each other; the parent compound of the morpholine family.
Technical-grade Morpholine technical grade refers to morpholine that is produced and used for industrial purposes, typically in applications where high purity is not a critical requirement.
Morpholine technical grade is a colorless, hygroscopic liquid free of suspended matter.

Morpholine technical grade is fully miscible with water and almost all common organic solvents, and slightly soluble in aliphatic hydrocarbons.
Morpholine technical grade is generally used as a chemical intermediate in corrosion inhibitors for steam boiler systems, but also has uses in pharmaceuticals, textiles, rubbers, catalysts, plasticizers, dyes, and agricultural and photographic chemicals.
Morpholine technical grade is a saturated organic heteromonocyclic parent and a member of morpholines.

Morpholine technical grade is a heterocyclic organic compound with the chemical formula C4H9NO.
Morpholine technical grade is a conjugate base of a morpholinium.
Morpholine technical grade, also known as 1, 4-oxazepine and diethylenimine oxide, is a kind of colorless alkaline oily liquid.

Morpholine technical grade smells of ammonia and has hygroscopicity.
Morpholine technical grade could evaporate with water vapor and miscible with water.
Morpholine technical grade is Soluble in acetone, benzene, ether, pentane, methanol, ethanol, carbon tetrachloride, propylene glycol and other organic solvents.

Morpholine technical grade Vapor could form an explosive mixture with air and the explosion limit is 1.8% to 15.2% (volume fraction).
Morpholine technical grade is a secondary amine, and at the same time it has the property of inorganic acid and organic acid, so that it can generate salt and amide.
Morpholine technical grade contains secondary amine groups and it has all the typical reaction characteristics of the secondary amine groups.

Morpholine technical grade can react with inorganic acid to form a salt, and also can react with organic acid to form salt or amide.
Morpholine technical grade is a cyclic amine that consists of a six-membered ring containing both oxygen and nitrogen atoms.
Morpholine technical grade is known for its corrosion-inhibiting properties, making it useful in various industries, such as the production and transportation of water and steam.

Morpholine technical grade helps protect metal surfaces from corrosion.
Morpholine technical grade is sometimes used in water treatment formulations for cooling and heating systems to prevent corrosion and scale formation.
Morpholine technical grade can carry out alkylation reactions and it also carry out ketone reaction or Willgerodt reaction with ethylene oxide.

Because of the unique chemical properties of Morpholine technical grade, it has become one of the important petrochemical products with important commercial application.
Morpholine technical grade can be applied to produce rubber vulcanization accelerators such as NOBS, DTOS and MDS.
Morpholine technical grade is also applied to produce anti-corrosives, anti-corrosion agents, detergents, detergents, analgesics, local anesthetics, sedatives, respiratory and vascular stimulants, surfactants, optical bleach, fruit preservatives, and textile dyeing auxiliaries.

Morpholine technical grade also has a wide range of applications in the field of rubber, pharmaceuticals, pesticides, dyes, coatings and other industries.
In medication it could be applied in the production of Morpholine technical grade, virus Ling, ibuprofen, cough must, naproxen, dichloroaniline, sodium phenylacetate and other important drugs.
The two main production method of Morpholine technical grade are DEA method (diethanolamine method) and DEA method (diethylene glycol method).

Morpholine technical grade is noteworthy that new polymer monomer acrylic morpholine has obtained a rapid development in recent years.
Morpholine technical grade could be produced from the reaction between acrylic acid and morpholine.
Morpholine technical grade is a kind of water-soluble monomer, and it is still water-soluble after the polymerization.

So Morpholine technical grade could be applied for the modification of aqueous polymers.
Besides, acrylic Morpholine technical grade is widely used as a reactive diluent for UV curable resins.
It is employed in gas scrubbing processes to remove acidic impurities, such as hydrogen sulfide, from industrial gases.

Morpholine technical grade is used as a catalyst in the production of rubber and polymers.
Morpholine technical grade helps control the molecular weight and structure of polymer products.
In the textile industry, Morpholine technical grade can be used as a solvent in dyeing processes and as a stabilizer for dyes.

Morpholine technical grade may be added to gasoline and lubricants to inhibit corrosion in engines and fuel systems.
Morpholine technical grade is an organic chemical compound having the chemical formula O(CH2CH2)2NH.
This heterocycle features both amine and ether functional groups.

Because of the amine, Morpholine technical grade is a base; its conjugate acid is called morpholinium.
For example, treating Morpholine technical grade with hydrochloric acid makes the salt morpholinium chloride.
Morpholine technical grade is a colorless liquid with a weak, ammonia- or fish-like odor.

Morpholine technical grade is attributed to Ludwig Knorr, who incorrectly believed it to be part of the structure of morphine.
Morpholine technical grade is colorless water-absorbing oily liquid and it smells ammonia.
Morpholine technical grade is soluble in water and methanol, ethanol, benzene, acetone, ether, ethylene glycol and other commonly used solvents.

Morpholine technical grade is a colorless to yellow liquid with a weak ammonia or fish-like odor.
The reactivity of Morpholine technical grade is mainly due to its secondary amine group.
Morpholine technical grade readily undergoes organic condensations, alkylations, and arylations, resulting in the formation of various N-substituted morpholine compounds.

Ethers are relatively chemically inert, hence the oxygen is of relatively little consequence except as a member of the heterocyclic ring.
Morpholine technical grade, Reagent, ACS is used as an industrial pH modifier and corrosion inhibitor.
Morpholine technical grade is also used as organic synthetic building block and a laboratory solvent.

As an ACS grade quality reagent, Morpholine technical grade is chemical specifications are the de facto standards for chemicals used in many high-purity applications and typically designate the highest quality chemical available for laboratory use.
Spectrum Chemical manufactured Reagent ACS grade products meet the toughest regulatory standards for quality and purity.
Morpholine technical grade is a volatile organic chemical compound with the chemical formula C4H9NO.

Morpholine technical grade has the properties of two functional groups, amine and ether.
In fact, Morpholine technical grade is a chemically stable amino ether. Due to the presence of amines, morpholine is a base whose conjugated acid is morpholinium.
While higher-purity grades are used in pharmaceuticals, technical grade morpholine may find application in certain aspects of pharmaceutical manufacturing.

Morpholine technical grade can be used in the formulation of adhesives and sealants to improve performance and stability.
Morpholine technical grade is widely used in the production of many chemicals as a corrosion inhibitor and also in detergents.
Shanghai Chemex is one of the most reputable suppliers of this chemical in the world.

Morpholine technical grade is a colorless liquid with a fishy odor that has a flashpoint of 100 degrees Fahrenheit and is corrosive to tissues, soluble in water, and denser than water.
Morpholine technical grade is soluble in acetone, benzene, ether, pentane, methanol, ethanol, carbon tetrachloride, propylene glycol, and other organic solvents, and its vapors are heavier than air and can form explosive mixtures with air.
The most important application of morpholine is as an intermediate in the production of accelerators used in the rubber industry.

Accelerators will be added to the rubber before production to speed up vulcanization.
Another application of this chemical compound is in medicine and the pharmaceutical industry.
Morpholine technical grade is used to produce a variety of local anesthetics, sedatives, analgesics, vascular and respiratory stimulants.

Morpholine technical grade is an extremely versatile chemical with many important applications.
Morpholine technical grade is used as an intermediate in the manufacture of rubber chemicals and optical brighteners.
Morpholine technical grade is also used extensively as a corrosion inhibitor in steam boiler systems.

Morpholine technical grade is often used as a solvent in various industrial processes, such as the extraction of natural gas and the purification of pharmaceuticals.
Morpholine technical grade is employed as a corrosion inhibitor in steam boiler systems and other water-based cooling systems to help prevent corrosion of metal components.
Morpholine technical grade is used in the production of adhesives and sealants.

Morpholine technical grade is utilized in the natural gas industry for sweetening, which involves removing hydrogen sulfide and carbon dioxide from natural gas streams.
Morpholine technical grade can be found in some formulations of paints and coatings as a stabilizer or pH adjuster.
Morpholine technical grade is used in the rubber industry as an intermediate for the production of accelerators and as a curing agent.

Due to its favorable thermal stability and low freezing point, Morpholine technical grade is employed in heat transfer fluids in various industrial processes.
Morpholine technical grade is used in metal cleaning processes, particularly for removing rust and scale from metal surfaces.
Morpholine technical grade is employed as a building block in the synthesis of certain pharmaceuticals and agrochemicals.

Morpholine technical grade can be used in the paper and pulp industry as an additive in the pulping process.
Morpholine technical grade is used in the textile industry for printing and dyeing processes.
Due to its ability to inhibit corrosion, Morpholine technical grade is added to cooling and antifreeze fluids in some applications.

In laboratories, Morpholine technical grade can be used as a reagent in chemical synthesis and analysis.
Morpholine technical grade derivatives are sometimes employed in biomedical research for their potential pharmacological activities.
Morpholine technical grade can function as a plasticizer in the production of certain plastics.

Morpholine technical grade serves as an intermediate in the synthesis of other chemicals.
Morpholine technical grade can be used in the production of rubber accelerators, optical brighteners, and certain pharmaceuticals.
Morpholine technical grade is sometimes used as a pH regulator in water treatment processes.

In some polymerization processes, Morpholine technical grade can be used as a catalyst or an aid to control the polymerization reaction.
Morpholine technical grade is used in gas scrubbing systems to remove acidic components, such as hydrogen sulfide, from gas streams.
Morpholine technical grade is mainly applied for the anti-corrosion of iron, copper, zinc, lead and other metals.

Morpholine technical grade remains at its starting stage in China, but outside the country, a considerable proportion of Morpholine are used as a kind of anti-rust agent for metal gas to prevent the metal corrosion caused by atmosphere and it has been widely used in the field of mechanical instruments, automobiles, medical equipment and others.
The metal atmospheric rust inhibitor used earlier such as dicyclohexylamine nitrite and cyclohexylamine do harm to the human body and they are more environmentally toxic.
Morpholine technical grade finds application in the textile industry as a catalyst for the production of certain dyes and as a stabilizer for emulsions.

Melting point: -7--5 °C (lit.)
Boiling point: 126.0-130.0 °C 129 °C (lit.)
Density: 0.996 g/mL at 25 °C (lit.)
vapor density: 3 (vs air)
vapor pressure: 31 mm Hg ( 38 °C)
refractive index: n20/D 1.454(lit.)
Flash point: 96 °F
storage temp.: Store below +30°C.
solubility: water: miscible
form: Liquid
pka: 8.33(at 25℃)
color: APHA: ≤15
Specific Gravity: 0.996
Odor: Characteristic amine-like odor
PH: 11.2 (H2O)(undiluted)
explosive limit: 1.4-15.2%(V)
Water Solubility: MISCIBLE
FreezingPoint: -4.9℃
Sensitive: Hygroscopic
Dielectric constant: 7.3(25℃)
LogP: -0.860

Morpholine technical grade dissolved in water neutralizes acids in exothermic reactions to form salts plus water.
Morpholine technical grade undergoes most chemical reactions typical for other secondary amines, though the presence of the ether oxygen withdraws electron density from the nitrogen, rendering it less nucleophilic (and less basic) than structurally similar secondary amines such as piperidine.
Morpholine technical grade forms a stable chloramine.

Colorless Liquid Morpholine technical grade Chemical has extensive application in water treatment plants.
This hygroscopic liquid chemical easily dilutes in water and most of organic solvents.
But it does not dissolve in alkaline liquid content.

This Morpholine technical grade has a distinctive smell that resembles the odor of ammonia.
Morpholine technical grade has a broad scope of applications.
Morpholine technical grade serves as an effective antioxidant, a chemical intermediate, gloss, and wax emulsifier in different industries.

Morpholine technical grade also serves as a polymerization prevention factor and as a paper preservative.
This liquid Morpholine technical grade is accessible in pure form.
Morpholine technical grade is a chemical intermediate used in the production of pharmaceuticals, agrochemicals, and surfactants.

This 97% pure technical grade compound is typically used for research purposes.
Morpholine technical grade should be handled with care as it may cause skin irritation or eye damage upon contact.
May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.

Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Morpholine technical grade did not produce an increase in tumors in rats that inhaled from 10 to 150 ppm for 2 years.
No tumors were seen in rats fed 5000 ppm Morpholine technical grade for 8 weeks and observed for their lifetime.

Morpholine technical grade fed concurrently with sodium nitrate increased the numbers of hepatocellular carcinomas and sarcomas of the liver and lungs of rats and mice, probably mediated through the formation of N-nitrosomorpholine.
Morpholine technical grade is used in water treatment processes to control pH and prevent corrosion in water systems.
Morpholine technical grade finds applications in electroplating processes, where it can be used as a buffering agent.

Morpholine technical grade is utilized in the production of certain types of inks as a stabilizer and pH regulator.
Morpholine technical grade is sometimes used as an additive in gasoline to improve combustion efficiency.
Morpholine technical grade derivatives are employed in the synthesis of herbicides and pesticides.

Morpholine technical grade derivatives can be used in the manufacture of photographic chemicals.
In some wood preservation treatments, Morpholine technical grade can be included to protect against decay and insects.
Morpholine technical grade is used in the production of certain synthetic resins.

In the oil and gas industry, Morpholine technical grade is sometimes employed as a scavenger for hydrogen sulfide.
Morpholine technical grade can be used in the leather industry as a dyeing assistant.
Morpholine technical grade can be involved in processes related to the desulfurization of gasoline.

Morpholine technical grade may be used as an additive in coolant formulations for specific applications.
In natural gas storage, Morpholine technical grade can be employed to prevent corrosion in storage tanks and pipelines.
Morpholine technical grade derivatives can be used in certain polymerization processes for cross-linking polymers.

Morpholine technical grade is used in cooling water treatment to control corrosion and scale formation in cooling systems.
In the cosmetics industry, Morpholine technical grade is sometimes used as a humectant to retain moisture in certain formulations.
Morpholine technical grade derivatives have been investigated for their antifungal properties and may find applications in antifungal formulations.

Morpholine technical grade can be added to deicing fluids to enhance their performance in preventing ice formation on surfaces.
Morpholine technical grade derivatives may be used in the production of certain materials for photovoltaic devices.
Morpholine technical grade can be added to gasoline formulations to reduce vapor pressure, which is important for controlling emissions.

Morpholine technical grade is used as a curing agent for epoxy resins, contributing to the formation of a solid and durable material.
Morpholine technical grade derivatives can be involved in the synthesis of certain fertilizers.
Morpholine technical grade may be used as an additive in detergent formulations for its stabilizing and buffering properties.

Morpholine technical grade derivatives can be employed as octane enhancers in gasoline formulations.
In the printing industry, Morpholine technical grade is used in the preparation of certain solutions and inks.
Morpholine technical grade-based compounds can be used in waterborne coatings to enhance their performance.

Morpholine technical grade can be found in some tobacco products as an additive.
Morpholine technical grade is used in anti-corrosion paint formulations to protect metal surfaces.

In metal processing, Morpholine technical grade can be employed in pickling solutions to remove oxides and scales from metal surfaces.
Morpholine technical grade derivatives can serve as catalysts in hydroformylation reactions in the production of aldehydes.

Production method:
Morpholine technical grade could be produced by diethanolamine dehydration cyclization derived from sulfuric acid.
Add diethanolamine to the water reaction pot and drop sulfuric acid in the temperature of 60 ℃, then when the temperature heat at 185-195 ℃, incubate it for 30min.
Cool it to under 60℃ and drop sodium hydroxide solution to pH = 11.

The next steeps are cooling, filtering, filtrating distillation, collecting the following fractions below 130℃.
The content of spermine is suppose to reach more than 99.5%. The method is easy to obtain raw materials, so it has become the main method of producing morpholine in the world.
Morpholine technical grade also could be produced in the catalytic reaction between dioxane and ammonia gas.

The preparation method is that we could get Morpholine from the presence of sulfuric acid dehydration cyclization diethanolamine In the presence of sulfuric acid ; then add diethanolamine into the reaction kettle and add H2SO4 at a temperature of below 6 °C, then heat it to 185-195 °C for 30 minutes, cool to 60 °C.

Drop NaOH solution to pH = 11, and the last two steeps is cooling and filtrating.
Morpholine technical grade could be collected from the fraction below 130 °C.
The method is easy to obtain raw materials, thus it is the main method of producing morpholine around the world.

Uses:
Morpholine technical grade is used for the analysis of reagents and resins, wax, casein, shellac and a variety of solvents solvent.
Morpholine technical grades used as corrosion inhibitors, insecticides, antiseptics, intermediate for rubber-processing chemicals; corrosion inhibitors; waxes and polishes; optical brighteners.
Morpholine technical grade reacts readily with fatty acids, forming soaps used in the formulation of self-polishing waxes and polishes and in coatings for the food industry.

Morpholine technical grade and TV-ethyl morpholine are used as catalysts in the manufacture of polyurethane foams.
Morpholine technical grade derivatives are utilized in pharmaceutical applications, as bactericides, fungicides, and herbicides, and as separating agents for oils.
Morpholine technical grade is used as a chemical emulsifier in the process of waxing fruit.

Naturally, fruits make waxes to protect against insects and fungal contamination, but this can be lost as the fruit is cleaned.
A small amount of new wax is applied to replace Morpholine technical grade.
Morpholine technical grade is used as an emulsifier and solubility aid for shellac, which is used as a wax for fruit coating.

The European Union has forbidden the use of morpholine in fruit coating.
Morpholine technical grade has been used as a reference standard for the identification of the analyte in water by gas chromatography-mass spectrometry (GC-MS).
Morpholine technical grade may be used as a reference standard for the determination of the analyte in fruit-based soft drinks, in natural waters and in vegetables by liquid chromatography-mass spectrometry (LC-MS) and in drugs by GC-MS.

Morpholine technical grade is widely used as a neutralizing amine to prevent carbonic acid corrosion in steam boiler systems.
Morpholine technical grade evaporates with the vapor in the system, and when the vapor becomes liquid, it liquefies with it, thus protecting the lines.
Morpholine technical grade vapors can prevent corrosion of silver and other metals, as well as obscuring their surfaces by acids such as sulfur dioxide and hydrogen sulfide.

In the agricultural industry, this material will be used as a protection and cover against insects and fungal contamination for fruit.
Morpholine technical grade derivatives are utilized in the synthesis of certain agricultural chemicals, including herbicides and pesticides.
Morpholine technical grade derivatives can be employed as additives in gasoline to control engine knock and improve fuel performance.

Morpholine technical grade derivatives act as catalysts in hydroformylation reactions, a process used in the production of aldehydes.
Morpholine technical grade can be part of aqueous cleaning solutions due to its solubility in water and ability to function as a stabilizer.
Morpholine technical grade can also be used as a component in agricultural fungicides and microbial removal.

Morpholine technical grade is one of the most widely used chemical compounds in various industries.
That is why many industries are looking for high-quality Morpholine technical grade.
In research and industry, Morpholine technical grade is used as a solvent for chemical reactions due to its low cost and high polarity.

Morpholine technical grade is used in the production of inks as a stabilizer and pH regulator.
Morpholine technical grade applied in electroplating processes, where it serves as a buffering agent.
Found in some cosmetic formulations for its humectant properties, helping to retain moisture.

Morpholine technical grade derivatives are investigated for their antifungal properties and potential applications in antifungal formulations.
Morpholine technical grade is used as an additive in detergent formulations for its stabilizing and buffering properties.
Morpholine technical grade is used in the printing industry for the preparation of solutions and inks.

Morpholine technical grade added to gasoline formulations to reduce vapor pressure and control emissions.
Morpholine technical grade is used as a curing agent for epoxy resins, contributing to the formation of solid and durable materials.
Morpholine technical grade derivatives may be used in the production of materials for photovoltaic devices.

Morpholine technical grade derivatives can be employed as octane enhancers in gasoline formulations.
Morpholine technical grade derivatives are used in biomedical research for potential pharmacological activities.
Morpholine technical grade is used in the production of polyurethane foams, where it can serve as a stabilizer and contribute to the foam's properties.

Morpholine technical grade is used in the paper and pulp industry as an additive in the pulping process.
Morpholine technical grade derivatives may be used as softeners in the textile industry.
Employed in metal pickling processes to remove oxides and scales from metal surfaces.

Other derivatives are utilized in the textile and printing industry as adjuvants, whitening agents, stabilizers, ink eradicators, and paper conditioners.
Morpholine technical grade, also known as Diethylenimide Oxide, is an organic chemical compound used in organic synthesis.
Morpholine technical grade could produce salt after reacting with inorganic acid, and it also could produce salt or amide after reacting with organic acid.

Morpholine technical grade derivatives can function as oxidation stabilizers in gasoline formulations.
Morpholine technical grade is used as an auxiliary agent in textile printing processes.
Morpholine technical grade is employed in the electronics industry for various applications, including the production of electronic chemicals.

Morpholine technical grade is a common additive, in parts per million concentrations, for pH adjustment in both fossil fuel and nuclear power plant steam systems.
Morpholine technical grade is used because its volatility is about the same as water, so once it is added to the water, its concentration becomes distributed rather evenly in both the water and steam phases.
Morpholine technical grade is pH-adjusting qualities then become distributed throughout the steam plant to provide corrosion protection.

Morpholine technical grade is often used in conjunction with low concentrations of hydrazine or ammonia to provide a comprehensive all-volatile treatment chemistry for corrosion protection for the steam systems of such plants.
Morpholine technical grade decomposes reasonably slowly in the absence of oxygen at the high temperatures and pressures in these steam systems.
Morpholine technical grade is generally considered an additive and is used for a variety of purposes.

Morpholine technical grade is often used as a corrosion inhibitor in steam boiler systems and water cooling systems to prevent corrosion of metal components.
Morpholine technical grade is employed in the natural gas industry for the removal of acidic components like hydrogen sulfide and carbon dioxide from natural gas streams.
Morpholine technical grade serves as a solvent in different industrial processes, including the extraction of natural gas and the purification of pharmaceuticals.

Morpholine technical grade is used as a pH regulator in water treatment processes and various industrial applications.
Morpholine technical grade is utilized in the production of rubber accelerators, curing agents, and as a component in certain polymerization processes.
Morpholine technical grade also can be alkylated, and it also could come up a ketone reaction or Willgerodt reaction with ethylene oxide.

Morpholine technical grade is made by dehydrating ethanolamines. Its main use is as a rubber accelerator in manufacturing tires.
This process requires high temperature (300°F) and pressure, which increase the hazards.
Morpholine technical grade is also used as a boiler water additive, brightener for detergents, and corrosion inhibitor, in the preservation of book paper, in waxes and polishes, and in organic synthesis.

Morpholine technical grade used as the raw materials for rubber accelerator and fluorescent whitening agent.
Morpholine technical grade is the intermediates of fungicide dimethomorph and flumorpholine and organophosphate insecticide phosalphos.
Morpholine technical grade fatty acid salt can be used as the coating agent of fruits or vegetables epidermal coating agent, and it could inhibit the base respiration and prevent the epidermis from evaporation of water and epidermal atrophy.

Morpholine technical grade derivatives can be involved in the synthesis of certain fertilizers.
Morpholine technical grade may be used as an additive in coolant formulations for specific applications.
In natural gas storage, Morpholine technical grade can be employed to prevent corrosion in storage tanks and pipelines.

Morpholine technical grade derivatives can be used in certain polymerization processes for cross-linking polymers.
Morpholine technical grade is used in the leather industry as a dyeing assistant.
Morpholine technical grade is added to cooling and antifreeze fluids in some applications due to its ability to inhibit corrosion.

Morpholine technical grade can be involved in processes related to the desulfurization of gasoline.
Morpholine technical grade is the main raw materials of accelerator NOBS.
For analysis reagents and resins, wax, shellac and other solvents, used in the production of sodium sulfate.

Morpholine technical grade is Mainly used for the production of rubber vulcanization accelerator, but also for surfactant, textile auxiliaries, pharmaceuticals, pesticide synthesis.
Morpholine technical grade also used as a catalyst for polymerization of butadiene, corrosion inhibitors, optical bleach, the goods are dyes, resins, wax, early glue, casein and other solvents. At present, the total production of morpholine in the world is 3-4 million t/a.
Morpholine technical grade salts are also widely used.

Found in the formulation of adhesives and sealants in industries like construction.
Morpholine technical grade is used in heat transfer fluids due to its thermal stability and low freezing point.
Employed in metal cleaning processes, particularly for removing rust and scale from metal surfaces.

Morpholine technical grade is used in the textile industry for dyeing and printing processes.
Morpholine technical grade applied in processes related to desulfurization, gas scrubbing, and as a scavenger for hydrogen sulfide.

Morpholine technical grade is used in certain formulations of paints and coatings as a stabilizer and pH regulator.
Found in the manufacture of certain photographic chemicals.
Morpholine technical grade is used in cooling water treatment to control corrosion and scale formation.

Morpholine technical grade and its derivatives serve as intermediates in the synthesis of pharmaceuticals.
Included in gasoline formulations to improve combustion efficiency and reduce vapor pressure.
Morpholine technical grade is used in wood preservation treatments to protect against decay and insects.

Morpholine technical grade added to certain antifreeze formulations to inhibit corrosion.
Morpholine technical grade is used as a humectant in cosmetics to retain moisture.
Morpholine technical grade is added to deicing fluids to enhance their performance.

Morpholine technical grade derivatives can be involved in the synthesis of certain fertilizers.
Morpholine technical grade is commonly used to generate enamines.
Morpholine technical grade is widely used in organic synthesis.

For example, Morpholine technical grade is a building block in the preparation of the antibiotic linezolid, the anticancer agent gefitinib (Iressa) and the analgesic dextromoramide.
Morpholine technical grade salts like morpholine hydrochloride (10024-89-2) are the organic synthesis of intermediates.

Safety Information:
Morpholine technical grade can cause irritation to the skin and eyes upon direct contact.
Morpholine technical grade is important to use appropriate personal protective equipment (PPE), such as gloves and goggles, to minimize the risk of skin and eye exposure.
Morpholine technical grade vapors may cause respiratory irritation.

Adequate ventilation should be maintained in areas where the compound is handled, and respiratory protection may be necessary in situations with high concentrations of vapors.
Some individuals may develop sensitization to morpholine after repeated exposure, leading to allergic reactions.
Precautions, such as using protective clothing, can help minimize the risk of sensitization.

Morpholine technical grade technical grade is classified as harmful if swallowed.
Ingestion can lead to adverse health effects, and the severity of these effects depends on factors such as the amount ingested and individual susceptibility.

Environmental Impact:
Morpholine technical grade may have environmental implications.
Morpholine technical grade is important to prevent its release into the environment, as it can be toxic to aquatic organisms and may have adverse effects on ecosystems.

Morpholine technical grade itself is not highly flammable, it should be stored away from sources of ignition.
Fire safety measures should be in place, and firefighting personnel should be aware of the chemical's properties in case of a fire.

Synonyms:
MORPHOLINE
110-91-8
1-Oxa-4-azacyclohexane
Diethylene oximide
Tetrahydro-1,4-oxazine
Diethylenimide oxide
Diethyleneimide oxide
Diethylene imidoxide
Drewamine
Tetrahydro-2H-1,4-oxazine
Tetrahydro-p-oxazine
p-Isoxazine, tetrahydro-
morpholin
Tetrahydro-1,4-isoxazine
BASF 238
Caswell No. 584
2H-1,4-Oxazine, tetrahydro-
4H-1,4-Oxazine, tetrahydro-
138048-80-3
NSC 9376
Tetrahydro-p-isoxazine
CCRIS 2482
HSDB 102
EINECS 203-815-1
UNII-8B2ZCK305O
EPA Pesticide Chemical Code 054701
BRN 0102549
8B2ZCK305O
DTXSID2025688
CHEBI:34856
AI3-01231
NSC-9376
MFCD00005972
C4H9NO
Tetrahydro-4H-1-4-oxazine
DTXCID305688
EC 203-815-1
4-27-00-00015 (Beilstein Handbook Reference)
MORPHOLINE (IARC)
MORPHOLINE [IARC]
MORPHOLINE-2,2,3,3,5,5,6,6-D8
tetrahydro-14-iso-xazine
1,4-oxazinane
CAS-110-91-8
MORPHOLINE,REAG
MORPHOLINE, PRACT
UN2054
morphline
Morpholine; Molsidomine Imp. E (EP); Molsidomine Impurity E
morpho line
morpholine-
6LR
Morpholine (BASF)
4H-1, tetrahydro-
MORPHOLINE [MI]
Morpholine [UN2054] [Flammable liquid]
MORPHOLINE [FCC]
DIEYTHYLENE OXIMIDE
MORPHOLINE [HSDB]
MORPHOLINE [INCI]
Morpholine on Rasta Resin
WLN: T6M DOTJ
NCIMech_000154
Tetrahydro-1, 4-isoxazine
NCIOpen2_007748
Oprea1_317540
Tetryhydro-2H-1,4-oxazine
Tetrahydro-4H-1,4-Oxazine
BIDD:ER0297
Morpholine, analytical standard
CHEMBL276518
NSC9376
AMY22834
BCP24054
STR00194
Tox21_202450
Tox21_303240
TETRAHYDRO-2H-1, 4-OXAZINE
AKOS000118829
Morpholine, ACS reagent, >=99.0%
Morpholine, ReagentPlus(R), >=99%
DB13669
NA 2054
UN 2054
USEPA/OPP Pesticide Code: 054701
NCGC00249227-01
NCGC00256942-01
NCGC00259999-01
Morpholine, p.a., ACS reagent, 99.0%
Morpholine [UN2054] [Flammable liquid]
FT-0628993
M0465
EN300-18064
Morpholine purified by distillation from glass
Morpholine, purified by redistillation, >=99.5%
Q410243
J-522715
F2190-0339
InChI=1/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H
ScavengePore(TM) phenethyl morpholine, macroporous, 40-70 mesh, extent of labeling: 0.7-1.5 mmol/g loading
StratoSpheres(TM) PL-MPH resin, 50-100 mesh, extent of labeling: 3.0-4.0 mmol/g loading, 1 % cross-linked
MPEG 1000
MPEG 1000
Polyglykol M 1000
Methyl polyglycol
Monomethoxy polyethylene glycol 1000
Methoxy Polyethylene Glycol 1000
CARBOWAX Methoxypolyethylene Glycol (MPEG)
Carbowax MPEG 1000
mpeg 1000

Synonyms: MPEG 1000, mPEG 1000, Polyglykol M 1000, Monomethoxy polyethylene glycol 1000, Methoxy PEG-25, Methoxy Polyethylene Glycol 1000, Methyl polyglycol 1000, POLYETHYLENE GLYCOL MONOMETHYL ETHER, Polyethylenglykolmonomethylether 1000, CARBOWAX Methoxypolyethylene Glycol (MPEG) 1000




Composition
Monomethoxy polyethylene glycol

Molecular Structure: CH3(OCH2CH2)nOH

EC / List no.: 618-394-3

CAS no.: 9004-74-4

INCI-designation: Methoxy PEG-25


PRODUCT FUNCTION: Intermediate & process aid

CHEMICAL TYPE: Methoxy Polyethylene glycol


APPLICATIONS of MPEG 1000
Chemical synthesis
Concrete Admixture
Construction
Dry mix mortars
General industrial applications
Grinding Aids
Industrial Lubrication
Lubes and Greases
Paint additive manufacturing
Paint additive manufacturing
Plaster Boards
Plastic & elastomer synthesis
Resin synthesis
Superplasticizer



Applications of MPEG 1000:
MPEG 1000 is a raw material for 3rd generation superplasticizers.

MPEG 1000 is an effective component of PCE superplasticizer admixtures.

MPEG 1000 is an intermediate in synthesizing superplasticizers (concrete admixtures) and pigment dispersants.

MPEG 1000 is used as a raw material in producing polycarboxylate ether superplasticizers.

The polycarboxylic acid superplasticizer is prepared with acrylic acid, MPEG 1000, and sodium vinyl sulfonate, and through the esterification of acrylic acid and MPEG 1000 in the water bath to prepare intermediate polyglycol acrylate, and the subsequent free radical polymerization of polyglycol acrylate, sodium vinyl sulfonate, and acrylic acid under the action of initiator in water solution.

The preparation process has easily controlled conditions, simple operation, no pollution, low cost, and other features.
The product of the present invention may be used as a concrete superplasticizer suitable for different kinds of cement.


Methoxy polyethylene glycol ether with a molecular weight of 1000 g/mole is commonly used as a chemical intermediate in producing alkyd emulsions and HEUR thickeners.

MPEG 1000 is used for a wide variety of chemical reactions.

MPEG 1000 acts as end-capping and hydrophilic components with isocyanates and polyester

When MPEG 1000 is reacted with unsaturated monomers like acrylic or methacrylic acid, esters are formed, which can be copolymerized to increase hydrophilicity and improve the dispersing properties of polymers in water.

Methoxy polyethylene Glycol (MPEG) 1000 is used in pressure-sensitive and thermoplastic adhesives.
MPEG 1000 possesses lubricity & humectant properties and maintains wet-tack strength

Due to the low concentration of diols in poly-glycol M-types, almost no di-esters form during the reaction with acrylic or methacrylic acid.
In the USA, some M-type polyglycols are used for pharmaceutical applications.



Product properties*)
MPEG 1000 is a waxy white to slightly yellowish solid at room temperature.

MPEG 1000 can be supplied as melt in heated tank trucks or solid in steel drums.

MPEG 1000 is soluble in water and solvents like acetate and methanol.

MPEG 1000 can be considered a high molecular alcohol and, therefore, displays typical chemical reactions of alcohols.


MPEG 1000 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether (M-PEG) that is entirely water-soluble.


MPEG 1000 PRODUCT FUNCTION: Intermediate


Product data*)
Water content (DIN 51777) % w/w: max. 0.1
Color Hazen (10% w/w in water) (EN 1557): max. 30
pH (5 %i w/w in water) (DIN 19268): 5,0 – 7,0
Hydroxyl number (DIN 53240) mg KOH/g: 53 - 58
Molecular weight g/mol: 970 - 1060
Pour point (ISO 3016) °C: ca. 40
Viscosity at 20°C (50% w/w in water) (DIN 51562) mm²/s: about 27
Diol content (HPLC) area-%: 0,5 – 2,0





Item Specification Unit Method

Consistence at 20°C wax-like Ataman
visual

Hazen color 10% a.i. in water max. 30 EN 1557

pH value 5% in water: 5.0 - 7.0 DIN EN 1262

Water content: max. 0.1 % DIN 51777
Karl-Fischer

OH value: 53 - 58 mgKOH/g DIN 53240

Molar mass: 970 - 1060 g/mol Ataman
calculated of OH value

Diole content: max. 2.0 area-% Ataman
HPLC



Storage
When stored in a cold, dry place in a closed container, MPEG 1000 can be kept for at least two years.







Regulatory process names
Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy-


IUPAC names
2-methoxyethanol

Agent I3C8

Dodecaethylene glycol monomethyl ether

METHOXY POLYETHYLENE GLYCOL 1000

Methoxy Polyethylene Glycol 1000

Polietilenglicolmonometileter

Poly(oxy-1,2-ethanediyl), .alpha.-methyl-.omega.-hydroxy-

Poly(oxy-1,2-ethanediyl), a-methyl-w-hydroxy-

POLY(OXY-1,2-ETHANEDIYL), α-METHYL-ω-HYDROXY-

Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy-

POLYETHYLENE GLYCOL MONOMETHYL ETHER

polyethylene glycol monomethyl ether

Polyethylene glycol monomethyl ether; Carbowax Sentry Methoxypolyethylene glycol

Polyethylenglykolmonomethylether



Trade names
Dodecaethylene glycol monomethyl ether

Other names
Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy

polyethylene(4-6)glycolmonomethylether


This information is based on Ataman's present knowledge and is intended to provide general notes on our products and their uses.
It should not, therefore, be construed as guaranteeing specific properties of the products described or their suitability for a particular application.
Any existing industrial property rights must be observed.
The quality of our products is guaranteed under our General Conditions of Sale.
Please check our website: www.atamankimya.com





MPEG 1000
Sodium phosphate monobasic; Monosodium dihydrogen orthophosphate, Monosodium phosphate, Sodium dihydrogen phosphate cas no:‎7558-80-7
MPEG 3000
MPEG 3000 is a chemical based on methoxy PEG-65.

MPEG 3000 provides lubricity and moisturizing properties to the final product in the formulations of Personal Care and Cosmetic products (For example, shaving foams and shaving gels)

MPEG 3000 is used in pressure-sensitive and thermoplastic adhesives to increase adhesion strength - while the adhesive is still wet.

MPEG 3000 maintains wet adhesion strength in isocyanate and polyester adhesives.

MPEG 3000 is also an intermediate raw material for producing new-generation superplasticizers (Polycarboxylate ones).


Methoxypolyethylene glycol 3000
Methoxy polyethylene glycol 3000

Polyethylene glycol monomethyl ether (MPEG) 3000

What is MPEG 3000?

CARBOWAX MPEG 3000
METHOXY PEG-65
METHOXY PEG-65 [INCI]
MPEG-65
PEG-65 METHYL ETHER
PEG-65 METHYL ETHER [INCI]
POLYETHYLENE GLYCOL 3000 MONOMETHYL ETHER
POLYETHYLENE GLYCOL MONOMETHYL ETHER (MW 1800)
POLYOXYETHYLENE (65) MONOMETHYL ETHER

MPEG 3000 Methoxy polyethylene Glycol by Ataman Chemicals is a methoxy PEG-65-based plasticizer.
MPEG 3000 is used in pressure-sensitive and thermoplastic adhesives.
Methoxy polyethylene Glycol MPEG 3000 possesses lubricity and humectant properties.
MPEG 3000 maintains wet-tack strength.

MPEG 3000 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether (M-PEG) entirely water-soluble.

MPEG 3000 is esterified with methacrylic acid to yield the corresponding polyglycol mono methacrylates used to polymerize polycarboxylate superplasticizers.


MPEG 3000 is a type of Methoxy polyethylene glycol with a Molecular Weight of 3000 that provides enhanced solvency, lubricity, hygroscopicity, and slightly more hydrophobic solvent properties.

MPEG 3000 is an essential raw material in adhesives, chemical intermediates, inks and dye carriers, lubricants, soaps, and detergents​​.

Poly(ethylene glycol) methyl ether 3000 MW:
MPEG 3000 is a chain transfer agent to synthesize amphiphilic block copolymers by metal-free ring-opening oligomerization.
MPEG 3000 is a precursor to prepare retinoic acid-polyethylene glycol nanoassembly as an efficient drug delivery system.
MPEG 3000 is used to prepare diblock copolymer with polylactic acid, which can be applied in tissue engineering and drug delivery.

INCI Name: Methoxy PEG-65

Methoxy poly(ethylene glycol)
Polyethylene glycol monomethyl ether
mPEG
MPEG 3000
Polyglykol M 3000
Methyl polyglycol
Monomethoxy polyethylene glycol 3000
Methoxy Polyethylene Glycol 3000
CARBOWAX Methoxypolyethylene Glycol (MPEG)
Carbowax MPEG 3000
mpeg 3000
Methoxypolyethylene glycols
METHOXY POLYETHYLENE GLYCOL 3000
Poly(ethylene glycol methyl ether)
Poly(ethylene glycol) methyl ether
ETHYLENE GLYCOL 3000 MONOMETHYL ETHER POLYMER

Synonyms: MPEG 3000, mPEG 3000, Polyglykol M 3000, Monomethoxy polyethylene glycol 3000, Methoxy PEG-65, Methoxy Polyethylene Glycol 3000, Methyl polyglycol 3000, POLYETHYLENE GLYCOL MONOMETHYL ETHER, Polyethylenglykolmonomethylether 3000, CARBOWAX Methoxy polyethylene Glycol (MPEG) 3000, Methoxypolyethylene Glycol 3000

Uses of MPEG 3000:
Adhesives
Chemical intermediates
Inks and dye carrier
Lubricants
Soaps and detergents


Composition
Monomethoxy polyethylene glycol 3000

Molecular Structure: CH3(OCH2CH2)nOH

EC / List no.: 618-394-3

CAS no.: 9004-74-4

INCI-designation: Methoxy PEG-65


PRODUCT FUNCTION: Intermediate & process aid

CHEMICAL TYPE: Methoxy Polyethylene glycol

Product data*)
Consistency at 20°C: wax-like
Water content (DIN 51777) % w/w: max. 0.1
Color index Hazen color (10% w/w in water) (EN 1557): max. 30
pH (5 %i w/w in water) (DIN 19268): 5,0 – 7,0
Hydroxyl number (DIN 53240) mg KOH/g: 17.8 - 19.7
Molecular weight g/mol: 2850 - 3150
Pour point (ISO 3016) °C: about 52
Diol content (HPLC) area-%: max. 1,5


APPLICATIONS of MPEG 3000
Chemical synthesis
Concrete Admixture
Construction
Dry mix mortars
General industrial applications
Grinding Aids
Industrial Lubrication
Lubes and Greases
Paint additive manufacturing
Paint additive manufacturing
Plaster Boards
Plastic & elastomer synthesis
Resin synthesis
Superplasticizer



Applications of MPEG 3000:
MPEG 3000 is a raw material for 3rd generation concrete superplasticizers.

MPEG 3000 is an effective component of PCE superplasticizer admixtures.

MPEG 3000 is an intermediate in synthesizing superplasticizers (concrete admixtures) and pigment dispersants.

MPEG 3000 is used as a raw material in producing polycarboxylate ether superplasticizers.

The polycarboxylic acid superplasticizer is prepared with acrylic acid, MPEG 3000, and sodium vinyl sulfonate through the esterification of acrylic acid and MPEG 3000 in the water.


Methoxy polyethylene glycol ether with a molecular weight of 3000 g/mole is commonly used as a chemical intermediate in producing alkyd emulsions and HEUR thickeners.

MPEG 3000 is used for a wide variety of chemical reactions.

MPEG 3000 acts as end-capping and hydrophilic components with isocyanates and polyester

When MPEG 3000 is reacted with unsaturated monomers like acrylic or methacrylic acid, esters are formed, which can be copolymerized to increase hydrophilicity and improve the dispersing properties of polymers in water.

Methoxy polyethylene Glycol (MPEG) 3000 is used in pressure-sensitive and thermoplastic adhesives.
MPEG 3000 possesses lubricity & humectant properties and maintains wet-tack strength

Due to the low concentration of diols in poly-glycol M-types, almost no di-esters form during the reaction with acrylic or methacrylic acid.
In the USA, some M-type polyglycols are used for pharmaceutical applications.



Product properties*)
MPEG 3000 is a waxy white to slightly yellowish solid at room temperature.

MPEG 3000 is available as flakes.

MPEG 3000 is soluble in water and solvents like acetate and methanol.

MPEG 3000 can be considered a high molecular alcohol and, therefore, displays typical chemical reactions of alcohols.


MPEG 3000 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether (M-PEG) entirely water-soluble.


MPEG 3000 PRODUCT FUNCTION: Intermediate





Storage
When stored in a cold, dry place in a closed container, MPEG 3000 can be kept for at least two years.


Regulatory process names
Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy-


IUPAC names
2-methoxyethanol

Dodecaethylene glycol monomethyl ether

METHOXY POLYETHYLENE GLYCOL 3000

Methoxy Polyethylene Glycol 3000

Polietilenglicolmonometileter

Poly(oxy-1,2-ethanediyl), .alpha.-methyl-.omega.-hydroxy-

Poly(oxy-1,2-ethanediyl), a-methyl-w-hydroxy-

POLY(OXY-1,2-ETHANEDIYL), α-METHYL-ω-HYDROXY-

Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy-

POLYETHYLENE GLYCOL MONOMETHYL ETHER

polyethylene glycol monomethyl ether

Polyethylene glycol monomethyl ether; Carbowax Sentry Methoxypolyethylene glycol

Polyethylenglykolmonomethylether



Trade names
Dodecaethylene glycol monomethyl ether

Other names
Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy

polyethylene(4-6)glycolmonomethylether


OTHER PRODUCTS OF ATAMAN CHEMICALS THAT MIGHT BE OF INTEREST

MPEG 200
MPEG 300
MPEG 400
MPEG 600
MPEG 1000
MPEG 1500
MPEG 2000
MPEG 3000
MPEG 4000
MPEG 5000
MPEG 6000

This information is based on Ataman's present knowledge and is intended to provide general notes on our products and their uses.
It should not, therefore, be construed as guaranteeing specific properties of the products described or their suitability for a particular application.
Any existing industrial property rights must be observed.
The quality of our products is guaranteed under our General Conditions of Sale.
Please check our website: www.atamankimya.com

























MPEG 350
Mpeg 350 is PEG-6 methyl ether-based plasticizer.
Mpeg 350 maintains wet-tack strength and possesses lubricity and humectant properties.


CAS Number: 9004-74-4
Alternate CAS #251911-64-5
MDL number: MFCD00084416
Molecular Formula: CH₃O(CH₂CH₂O)nH
Classification: PEG / PPG, Ethoxylated compound, Glycol, Synthetic polymer


Mpeg 350 has an average molecular mass of 350.
Mpeg 350 provides enhanced solvency, lubricity, hygroscopicity and with slightly more hydrophobic solvent properties.
Mpeg 350 is a mono-functional methoxylated PEG (350) methacrylate monomer that features excellent wetting, water solubility, low Tg, and fast surface cure.


Mpeg 350 possesses lubricity and humectant properties.
Mpeg 350 maintains wet-tack strength.
Mpeg 350 is a high molecular weight product that belongs to methoxy polyoxyethylene glycols.


Mpeg 350 is intended mainly for the construction industry.
Mpeg 350 is a white compact paste or solid.
Mpeg 350 is a polymer with high solubility in water and a slight odour.


The active substance content in Mpeg 350 is about 100%.
Mpeg 350 denotes a methylated polyethylene glycol derivative with the linear formula: CH3O(CH2CH2O)nH.
Mpeg 350 with higher molecular weight is generally solid at room temperature.


The number after "PEG-" indicates the average number of molecular units -CH2-CH2-O-, for Methoxy PEG-10 this is 10 molecular units.
Methoxy PEG derivatives are used in numerous cosmetic formulations mainly as moisturizers.
"Methoxy" refers to a methyl-oxygen group (CH3-O-).


Dimethoxy-, trimethoxy- etc refer to two, three or more methoxy groups.
"PEG" refers to a PEG-(polyethylene glycol-) derivative.
The number behind "PEG-" (or the first number behind "PEG/...-") refers to the average number of molecular units -CH2-CH2-O-.



USES and APPLICATIONS of MPEG 350:
Mpeg 350 provides enhanced solvency, lubricity, hygroscopicity and with slightly more hydrophobic solvent properties.
Mpeg 350 is used for use in adhesives, chemical intermediates, inks and dye carrier, lubricants, and soaps and detergents.
Mpeg 350 is used for use in adhesives, chemical intermediates, and lubricants.


Cosmetic Uses of Mpeg 350: humectants
Mpeg 350 is used in pressure-sensitive and thermoplastic adhesives.
Mpeg 350 is used in various applications such as micelles for drug delivery as well as in modifications of therapeutic proteins to improve their pharmacokinetics.


Mpeg 350 is used in a wide range of lubricant applications due to their low volatility, solubility in water, and natural lubricity.
Mpeg 350 is non-staining to metal parts, textiles, and clothing and can be burned away leaving minimal residue.
Mpeg 350 is used in pressure sensitive and thermoplastic adhesives.


Mpeg 350 is recommended as a versatile intermediate for coatings and polymer modification.
Mpeg 350 is used in pressure sensitive adhesives and in thermoplastic adhesives.
Mpeg 350 can be used in the commercial concrete with high performance and high strength (above C60) which is mixed on site and transported remotely.


Mpeg 350 is soluble in water, ethanol and organic solvent.
Low steam pressure, stable for heat, Mpeg 350 is used as thickener and lubricant in textile printing and dyeing industry and daily chemical industry.
Mpeg 350 has good water solubility, wettability, lubricity, physiological inertia, no stimulation to human body, and is widely used in cosmetics and pharmaceutical industry.


The viscosity, hygroscopicity and structure of the products can be changed by selecting products with different molecular weight.
Products with relatively low molecular weight (molecular weight less than 2000) are suitable for wetting agents and consistency regulators for cream, lotion, toothpaste, and cream.


The products with relatively high molecular weight are suitable for lipstick, deodorant stick, soap, pick up soap, foundation and cosmetics.
As a cleaning agent, Mpeg 350 is also used as suspending agent and thickener.
In the pharmaceutical industry, Mpeg 350 is used as the matrix of ointment, emulsion, ointment, lotion and suppository.


Mpeg 350 also reacts with acrylic acid to make MPEG acrylic acid ester, which is the main raw material for the preparation of polycarboxylate superplasticizer.
Mpeg 350 is mainly used for the production of polycarboxylate ether (PCE) superplasticizers for concrete.


Mpeg 350 is used in esterification reactions, e.g. with methacrylic acid which is further subjected to a polymerization process.
The resulting products are the main components of concrete admixtures that reduce the amount of batch water in cement concrete.
Mpeg 350 is used in pressure sensitive and thermoplastic adhesives.


Comb polymers, resulting from emulsion polymerization using Mpeg 350, are used in paint and varnish production.
They are dispersants for organic and inorganic pigments.
Mpeg 350 is used Adhesives-PSA, Adhesives-Waterborne, Emulsions, Paint & Coatings-Waterborne, Protective Coatings, and Water Soluble Resins


Mpeg 350 is used Rubber & Elastomers, Food Processing, Packaging, Textiles, Household Products, and Wood Processing.
Mpeg 350 is used Paper & Paper Products, Cosmetics & Personal Care, Pharmaceuticals, Electronics, Printing & Inks, andElectroplating / Electropolishing.
Mpeg 350 is used Adhesives, Lubricants, Agriculture, Metalworking, Ceramics, Paints & Coatings, and Chemical Intermediates.


-Application of Mpeg 350:
*the intermediate is used in the synthesis of superplasticizers (concrete admixtures),
*the intermediate is used in the synthesis of pigment dispersants.


-Markets and applications of Mpeg 350:
*Building & Construction
*Concrete & mortar additives


-Applications of Mpeg 350:
*Adhesives
*Chemical Intermediates
*Inks and Dye Carrier
*Lubricants
*Plasticizer
*Soaps and Detergents


-Uses of Mpeg 350:
*Adhesives
*Chemical intermediates
*Inks and dye carrier
*Lubricants
*Soaps and detergents



FUNCTIONS OF MPEG 350:
*Humectant :
Mpeg 350 maintains water content of a cosmetic both in its packaging and on the skin
Mpeg 350 holds and retains moisture in cosmetic products
*Solvent :
Mpeg 350 dissolves other substances
*Hydrophilicity
*Water Soluble
*Plasticizers
*Superplasticizers
*Composition
*Methoxy polyethylene glycols
*Segment
*Specialty Products / Specialty additives
*Surfactants / Non-ionic surfactants



PROPERTIES AND APPLICATIONS OF MPEG 350:
1. Applied in building materials industry, as the raw material of cement water-reducing agent, reinforcing agent.
The synthetic polycarboxylate superplasticizer of the material has strong ability of cement particle dispersion, thereof, the product is characterized of low dosage, high water-reducing rate, excellent reinforce effect, good durability, not corrosive to rebar and environmentally friendly.
Can be applied in high-performance and high strength (above C60) commodity concrete for on site agitation and long distance conveying.

2. Mpeg 350 is soluble in water, ethanol and organic solvents.
Mpeg 350 is used as thickener and lubricant in the textile printing and dyeing industry and daily chemical industry due to its low vapor pressure and thermal stability.



ADVANTAGES OF MPEG 350:
*effective component of PCE type superplasticizing admixtures, very good hygroscopic properties,
*low diol content,
*paste/soft wax consistency,
*high solubility in water,
*slight odour.



FEATURES OF MPEG 350:
If the refined raw material and special catalyst are used, the impurity content of the product is low.
And the hydroxyl activity at the end of the molecular chain is retained to the greatest extent, with good hydrophilicity and hydroxyl reaction activity.
Mpeg 350 with higher molecular weight are generally solid at room temperature.



METHOXYPOLYETHYLENE GLYCOLS (MPEG):
Methoxypolyethylene Glycols (MPEG) are used in pharmacology and cosmetics production; detergent & household goods production (as soap bars glue, soluble agent in detergent pastes, fixing agent for odors in soaps and detergents, as additive in general cleaners, polishers, air fresheners, automatic dishwashing detergents); in production of textile supporting substances (as component of dispergators and protective solutions); in metal works industry (as agents for cleaning and polishing pastes, lubricating & cooling liquids).



PHYSICAL and CHEMICAL PROPERTIES of MPEG 350:
Molecular Formula: CH₃O(CH₂CH₂O)nH
Appearance: Colourless Thick Oil
Molecular Weight: N/A
Storage: 4°C
Solubility: Chloroform (Sparingly), Methanol (Slightly)
Physical Form: Liquid
Average Number of Repeating Oxyethylene Units: 7
Range of Average Molecular Weight: 335 – 365
Range of Average Hydroxyl Number, mg KOH/g: 154 – 167
Density, g/cm3 at 20°C: 1.09
Melting or Freezing Range, °C: -5 to 10
Solubility in Water at 20°C, % by weight: Complete
Viscosity at 100°C, cSt: 3.9
Heat of Fusion, Cal/g: 26
Molecular Weight: 350
Color: Clear, Colorless
Density: 1.0899 g/cm3 @ 20 °C (68 °F)
Flash Point: 182 °C (360 °F)
Freezing Point: -5 - 10 °C (23 - 50 °F)
Kinematic Viscosity: 3.9 mm2/s @ 98.9 °C (210.0 °F)

Odor: mild
pH: 4.5 - 7.5 @ 20 - 25 °C (68 - 77 °F)
Relative Vapor Density: > 10
Solubility in Water: soluble
Vapor Pressure: < 0.01 mmHg @ 20 °C (68 °F)
Appearance Form: liquid
Colour: colourless
Odour: No data available
Odour Threshold: No data available
pH: No data available
Melting point/freezing point:
Initial boiling point and boiling range: No data available
Melting point/range: 52 - 56 °C
Flash point: 182 °C - closed cup
Evaporation rate: No data available
Flammability (solid, gas) No data available
Upper/lower flammability or explosive limits: No data available
Vapour pressure: No data available
Vapour density: No data available
Relative density: No data available

Water solubility: No data available
Partition coefficient: n- octanol/water
Auto-ignitio temperature: No data available
Decomposition temperature: No data available
Viscosity: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
CAS: 9004-74-4
MF: C5H12O3
MW: 120.14698
EINECS: 618-394-3
Mol File: 9004-74-4.mol
Appearance: light yellow liquid
Hydroxyl value: 70.0-80.0mgKOH/g
Molecular weight: 350-750
Water: 0.50% max
PH(1%): 5.0-7.0



FIRST AID MEASURES of MPEG 350:
-Description of first aid measures:
*General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of MPEG 350:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of MPEG 350:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of MPEG 350:
-Control parameters:
--Exposure controls:
-Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
--Personal protective equipment:
*Eye/face protection:
Safety glasses with side-shields.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of MPEG 350:
-Conditions for safe storage, including any incompatibilities:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of MPEG 350:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
α-Methyl-ω-hydroxypoly(oxy-1,2-ethanediyl)
Polyoxyethylene Monomethyl Ether
Poly(Ethylene Oxide) Methyl Ether
Poly(Ethylene Oxide) Monomethyl Ether
Methoxy polyethylene glycol 350
MPEG-350
Methoxy polyethylene glycol
mono-methyl polyethylene glycol.


MPEG 500
Methoxypolyethylene glycol 500
Methoxy polyethylene glycol 500

What is MPEG 500?

MPEG 500 Methoxy polyethylene Glycol by Ataman Chemicals is a methoxy PEG-10-based plasticizer.
MPEG 500 is used in pressure-sensitive and thermoplastic adhesives.
Methoxy polyethylene Glycol MPEG 500 possesses lubricity and humectant properties.
MPEG 500 maintains wet-tack strength.

MPEG 500 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether (M-PEG) entirely water-soluble.

MPEG 500 is esterified with methacrylic acid to yield the corresponding polyglycol mono methacrylates used to polymerize polycarboxylate superplasticizers.


MPEG 500 is a type of Methoxy polyethylene glycol with a Molecular Weight of 500 that provides enhanced solvency, lubricity, hygroscopicity, and slightly more hydrophobic solvent properties.

MPEG 500 is an essential raw material in adhesives, chemical intermediates, inks and dye carriers, lubricants, soaps, and detergents​​.

Poly(ethylene glycol) methyl ether 500 MW:
MPEG 500 is a chain transfer agent to synthesize amphiphilic block copolymers by metal-free ring-opening oligomerization.
MPEG 500 is a precursor to prepare retinoic acid-polyethylene glycol nanoassembly as an efficient drug delivery system.
MPEG 500 is used to prepare diblock copolymer with polylactic acid, which can be applied in tissue engineering and drug delivery.

INCI Name: Methoxy PEG-10

Methoxy poly(ethylene glycol)
Polyethylene glycol monomethyl ether
mPEG
MPEG 500
Polyglykol M 500
Methyl polyglycol
Monomethoxy polyethylene glycol 500
Methoxy Polyethylene Glycol 500
CARBOWAX Methoxypolyethylene Glycol (MPEG)
Carbowax MPEG 500
mpeg 500
Methoxypolyethylene glycols
METHOXY POLYETHYLENE GLYCOL 500
Poly(ethylene glycol methyl ether)
Poly(ethylene glycol) methyl ether
ETHYLENE GLYCOL 500 MONOMETHYL ETHER POLYMER

Synonyms: MPEG 500, mPEG 500, Polyglykol M 500, Monomethoxy polyethylene glycol 500, Methoxy PEG-10, Methoxy Polyethylene Glycol 500, Methyl polyglycol 500, POLYETHYLENE GLYCOL MONOMETHYL ETHER, Polyethylenglykolmonomethylether 500, CARBOWAX Methoxy polyethylene Glycol (MPEG) 500, Methoxypolyethylene Glycol 500

Uses of MPEG 500:
Adhesives
Chemical intermediates
Inks and dye carrier
Lubricants
Soaps and detergents


Composition
Monomethoxy polyethylene glycol 500

Molecular Structure: CH3(OCH2CH2)nOH

EC / List no.: 618-394-3

CAS no.: 9004-74-4

INCI-designation: Methoxy PEG-10


PRODUCT FUNCTION: Intermediate & process aid

CHEMICAL TYPE: Methoxy Polyethylene glycol


Product data*)
Water content (DIN 51777) % m/m: max. 0.5
Color index [APHA] 10 % in water (EN 1557): max. 30
pH (5 % w/w in water) (DIN 19268): 5 – 7
Hydroxyl number (DIN 53240) mg KOH/g: 106 – 119
Molecular weight g/mol: 470 – 530
Pour point (ISO 3016) °C: about 12
Density at 50°C (DIN 51757) g/cm³: 1,072 – 1,076
Refractive index at 20°C (DIN 51423, Part 2): 1,460 – 1,462
Viscosity at 50°C (DIN 51562) mm²/s: 16 – 20


APPLICATIONS of MPEG 500
Chemical synthesis
Concrete Admixture
Construction
Dry mix mortars
General industrial applications
Grinding Aids
Industrial Lubrication
Lubes and Greases
Paint additive manufacturing
Paint additive manufacturing
Plaster Boards
Plastic & elastomer synthesis
Resin synthesis
Superplasticizer



Applications of MPEG 500:
MPEG 500 is a raw material for 3rd generation concrete superplasticizers.

MPEG 500 is an effective component of PCE superplasticizer admixtures.

MPEG 500 is an intermediate in synthesizing superplasticizers (concrete admixtures) and pigment dispersants.

MPEG 500 is used as a raw material in producing polycarboxylate ether superplasticizers.

The polycarboxylic acid superplasticizer is prepared with acrylic acid, MPEG 500, and sodium vinyl sulfonate through the esterification of acrylic acid and MPEG 500 in the water.


Methoxy polyethylene glycol ether with a molecular weight of 500 g/mole is commonly used as a chemical intermediate in producing alkyd emulsions and HEUR thickeners.

MPEG 500 is used for a wide variety of chemical reactions.

MPEG 500 acts as end-capping and hydrophilic components with isocyanates and polyester

When MPEG 500 is reacted with unsaturated monomers like acrylic or methacrylic acid, esters are formed, which can be copolymerized to increase hydrophilicity and improve the dispersing properties of polymers in water.

Methoxy polyethylene Glycol (MPEG) 500 is used in pressure-sensitive and thermoplastic adhesives.
MPEG 500 possesses lubricity & humectant properties and maintains wet-tack strength

Due to the low concentration of diols in poly-glycol M-types, almost no di-esters form during the reaction with acrylic or methacrylic acid.
In the USA, some M-type polyglycols are used for pharmaceutical applications.



Product properties*)
MPEG 500 is a waxy white to slightly yellowish solid at room temperature.

MPEG 500 can be supplied as melt in heated tank trucks or solid in steel drums.

MPEG 500 is soluble in water and solvents like acetate and methanol.

MPEG 500 can be considered a high molecular alcohol and, therefore, displays typical chemical reactions of alcohols.


MPEG 500 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether (M-PEG) entirely water-soluble.


MPEG 500 PRODUCT FUNCTION: Intermediate





Storage
When stored in a cold, dry place in a closed container, MPEG 500 can be kept for at least two years.


Regulatory process names
Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy-


IUPAC names
2-methoxyethanol

Dodecaethylene glycol monomethyl ether

METHOXY POLYETHYLENE GLYCOL 500

Methoxy Polyethylene Glycol 500

Polietilenglicolmonometileter

Poly(oxy-1,2-ethanediyl), .alpha.-methyl-.omega.-hydroxy-

Poly(oxy-1,2-ethanediyl), a-methyl-w-hydroxy-

POLY(OXY-1,2-ETHANEDIYL), α-METHYL-ω-HYDROXY-

Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy-

POLYETHYLENE GLYCOL MONOMETHYL ETHER

polyethylene glycol monomethyl ether

Polyethylene glycol monomethyl ether; Carbowax Sentry Methoxypolyethylene glycol

Polyethylenglykolmonomethylether



Trade names
Dodecaethylene glycol monomethyl ether

Other names
Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy

polyethylene(4-6)glycolmonomethylether


This information is based on Ataman's present knowledge and is intended to provide general notes on our products and their uses.
It should not, therefore, be construed as guaranteeing specific properties of the products described or their suitability for a particular application.
Any existing industrial property rights must be observed.
The quality of our products is guaranteed under our General Conditions of Sale.
Please check our website: www.atamankimya.com




MPEG 500 (METHOXY POLYETHYLENEGLYCOL 500)
MPEG 500, or Methoxy polyethylene glycol 500, is a chemical compound belonging to the class of polyethylene glycols (PEGs).
MPEG 500 (Methoxy polyethyleneglycol 500) is a polymer consisting of repeating ethylene oxide units with a molecular weight of around 500 Daltons.

CAS Number: 9004-74-4
EC Number: 618-394-3

Synonyms: MPEG 500, Methoxypolyethylene glycol 500, Polyethylene glycol monomethyl ether 500, Methoxy polyoxyethylene glycol 500, Methoxypoly(ethylene glycol) 500, Methoxy-poly(ethylene oxide) 500, PEG methyl ether 500, Methoxy-polyethylene oxide 500, Polyethylene glycol methyl ether 500, MPEG500, Methoxypolyethylene oxide 500, Methoxypolyoxyethylene glycol 500, Poly(ethylene glycol) methyl ether 500, MethoxyPEG 500, Methoxy-polyethylene glycol 500, Methoxypoly(ethylene oxide) 500, Methoxypolyethylene oxide 500, PEG monomethyl ether 500, Methoxypolyoxyethylene glycol 500, Polyethylene oxide methyl ether 500, Methoxy PEG 500, Methoxy polyethylene glycol 500, Methoxy-poly(ethylene glycol) 500, Methoxy polyethylene oxide 500, Methoxy polyoxyethylene glycol 500, Polyethylene glycol methyl ether 500, Methoxypolyethylene glycol monomethyl ether 500, Polyethylene glycol monomethyl ether 500, Methoxy polyethylene glycol monomethyl ether 500, MPEG 500, MethoxyPEG-500, Methoxypolyethylene glycol 5000, MPEG-5000, MethoxyPEG-5000, Polyethylene glycol monomethyl ether 5000, Methoxy polyoxyethylene glycol 5000, Methoxypoly(ethylene glycol) 5000, Methoxy-poly(ethylene oxide) 5000, PEG methyl ether 5000, Methoxy-polyethylene oxide 5000, Polyethylene glycol methyl ether 5000



APPLICATIONS


MPEG 500 (Methoxy polyethyleneglycol 500) is widely used as a solubilizing agent in pharmaceutical formulations.
MPEG 500 (Methoxy polyethyleneglycol 500) enhances the solubility of poorly soluble drugs, facilitating their formulation into oral solutions and suspensions.

Methoxy polyethylene glycol 500 serves as an emulsifier in the production of creams, lotions, and ointments in the cosmetics industry.
MPEG 500 (Methoxy polyethyleneglycol 500) improves the stability and texture of emulsions, resulting in smooth and uniform products.

In transdermal drug delivery systems, Methoxy polyethylene glycol 500 acts as a carrier for active pharmaceutical ingredients.
MPEG 500 (Methoxy polyethyleneglycol 500) ensures the controlled release of drugs through the skin for extended therapeutic effects.
Methoxy polyethylene glycol 500 is used as a lubricant in mechanical systems to reduce friction and wear.

MPEG 500 (Methoxy polyethyleneglycol 500) enhances the performance and longevity of machinery components, particularly in high-stress environments.
MPEG 500 (Methoxy polyethyleneglycol 500) is employed as a surfactant in industrial processes, aiding in the dispersion of particles and droplets.
Methoxy polyethylene glycol 500 is utilized in the production of adhesives and coatings for its binding properties.

MPEG 500 (Methoxy polyethyleneglycol 500) improves the adhesion and cohesion of adhesive formulations, leading to stronger bonds.
Methoxy polyethylene glycol 500 serves as a plasticizer in the manufacturing of polymer films and membranes.

MPEG 500 (Methoxy polyethyleneglycol 500) imparts flexibility and durability to plastic materials, enhancing their mechanical properties.
MPEG 500 (Methoxy polyethyleneglycol 500) is employed in the formulation of crop protection products such as herbicides and pesticides.

MPEG 500 (Methoxy polyethyleneglycol 500) aids in the dispersion and stability of active ingredients in agricultural formulations.
In the textile industry, Methoxy polyethylene glycol 500 is used as a softener and lubricant for fibers and fabrics.

MPEG 500 (Methoxy polyethyleneglycol 500) improves the handling and processing of textile materials during manufacturing.
MPEG 500 (Methoxy polyethyleneglycol 500) is utilized in the production of printing inks for its wetting and dispersing properties.

MPEG 500 (Methoxy polyethyleneglycol 500) ensures the even distribution of pigments and additives, resulting in high-quality prints.
MPEG 500 (Methoxy polyethyleneglycol 500) is employed in the synthesis of specialty polymers and resins for various applications.
MPEG 500 (Methoxy polyethyleneglycol 500) serves as a reactive intermediate in polymerization reactions, leading to the formation of tailored materials.

MPEG 500 (Methoxy polyethyleneglycol 500) finds application in the formulation of veterinary medicines and animal healthcare products.
MPEG 500 (Methoxy polyethyleneglycol 500) enhances the solubility and bioavailability of active ingredients in animal pharmaceuticals.

MPEG 500 (Methoxy polyethyleneglycol 500) is utilized in the preparation of diagnostic reagents and assays for medical testing.
MPEG 500 (Methoxy polyethyleneglycol 500) has diverse applications across industries, highlighting its versatility and importance in various manufacturing processes.

MPEG 500 (Methoxy polyethyleneglycol 500) is commonly used in the formulation of inkjet printing inks for its dispersing and wetting properties.
MPEG 500 (Methoxy polyethyleneglycol 500) ensures the uniform flow of ink and prevents clogging of print heads during printing.
In the production of detergents and cleaning products, Methoxy polyethylene glycol 500 acts as a surfactant, aiding in the removal of dirt and grease.

MPEG 500 (Methoxy polyethyleneglycol 500) improves the foaming and cleaning performance of household and industrial cleaners.
MPEG 500 (Methoxy polyethyleneglycol 500) is utilized in the fabrication of medical devices and implants for its biocompatibility and lubricating properties.

MPEG 500 (Methoxy polyethyleneglycol 500) reduces friction and irritation during medical procedures, enhancing patient comfort.
MPEG 500 (Methoxy polyethyleneglycol 500) is employed in the synthesis of hydrogels and biomaterials for tissue engineering and regenerative medicine applications.
MPEG 500 (Methoxy polyethyleneglycol 500) provides a biocompatible scaffold for cell growth and tissue regeneration.

In the production of specialty chemicals, Methoxy polyethylene glycol 500 serves as a versatile precursor for the synthesis of various organic compounds.
MPEG 500 (Methoxy polyethyleneglycol 500) enables the modification of chemical structures to impart specific functionalities to molecules.

MPEG 500 (Methoxy polyethyleneglycol 500) is utilized in the formulation of electronic materials such as conductive adhesives and encapsulants.
MPEG 500 (Methoxy polyethyleneglycol 500) enhances the electrical properties and performance of electronic components.
In the manufacturing of ceramics and refractory materials, Methoxy polyethylene glycol 500 is used as a binder and plasticizer.

MPEG 500 (Methoxy polyethyleneglycol 500) improves the workability and green strength of ceramic formulations, facilitating shaping and molding processes.
MPEG 500 (Methoxy polyethyleneglycol 500) finds application in the production of polymer composites for its reinforcing and compatibilizing effects.
MPEG 500 (Methoxy polyethyleneglycol 500) enhances the mechanical properties and stability of composite materials.
MPEG 500 (Methoxy polyethyleneglycol 500) is utilized in the formulation of coatings and paints for its film-forming properties and adhesion.

MPEG 500 (Methoxy polyethyleneglycol 500) provides a protective and decorative layer on surfaces, improving durability and appearance.
In the food industry, Methoxy polyethylene glycol 500 is used as an additive in food processing for its emulsifying and stabilizing properties.

MPEG 500 (Methoxy polyethyleneglycol 500) improves the texture and shelf life of food products such as sauces, dressings, and desserts.
MPEG 500 (Methoxy polyethyleneglycol 500) is employed in the production of personal care products such as hair care and skincare formulations.

MPEG 500 (Methoxy polyethyleneglycol 500) enhances the spreadability and moisturizing properties of cosmetic products.
MPEG 500 (Methoxy polyethyleneglycol 500) is utilized in the formulation of industrial lubricants and metalworking fluids for its friction-reducing and cooling properties.

MPEG 500 (Methoxy polyethyleneglycol 500) prolongs the lifespan of machinery and equipment by minimizing wear and heat generation.
MPEG 500 (Methoxy polyethyleneglycol 500) plays a crucial role in various industries, contributing to the development of innovative products and technologies.

In oral dosage forms, MPEG 500 (Methoxy polyethyleneglycol 500) enhances drug solubility and bioavailability.
MPEG 500 (Methoxy polyethyleneglycol 500) is inert and does not interact with most drug molecules.

MPEG 500 (Methoxy polyethyleneglycol 500) is biocompatible and well-tolerated by the skin.
MPEG 500 (Methoxy polyethyleneglycol 500) serves as a lubricant in mechanical systems, reducing friction and wear.

Its high thermal stability makes it suitable for use in various temperature ranges.
MPEG 500 (Methoxy polyethyleneglycol 500) forms stable emulsions with oils and other hydrophobic substances.
MPEG 500 (Methoxy polyethyleneglycol 500) can be easily dispersed in aqueous solutions to form homogeneous mixtures.

MPEG 500 (Methoxy polyethyleneglycol 500) is odorless and tasteless, making it ideal for pharmaceutical formulations.
MPEG 500 (Methoxy polyethyleneglycol 500) has a long shelf life and maintains its properties over a wide range of storage conditions.

MPEG 500 (Methoxy polyethyleneglycol 500) is often used as a carrier for active ingredients in transdermal drug delivery systems.
MPEG 500 (Methoxy polyethyleneglycol 500) undergoes minimal metabolism in the body, leading to low systemic exposure.

MPEG 500 (Methoxy polyethyleneglycol 500) exhibits good biocompatibility and is well-suited for use in medical devices and implants.
MPEG 500 (Methoxy polyethyleneglycol 500) is compatible with a variety of processing methods, including injection molding and extrusion.

In the textile industry, it is used as a sizing agent and lubricant for synthetic fibers.
Methoxy polyethylene glycol 500 is non-toxic and non-irritating to the skin and eyes.
MPEG 500 (Methoxy polyethyleneglycol 500) is widely used in the formulation of personal care products such as shampoos and conditioners.

MPEG 500 (Methoxy polyethyleneglycol 500) can be modified to tailor its properties for specific applications.
MPEG 500 (Methoxy polyethyleneglycol 500) is stable under a wide range of pH conditions, making it suitable for various formulations.
Methoxy polyethylene glycol 500 is a versatile polymer with diverse applications in pharmaceuticals, cosmetics, and industrial processes.



DESCRIPTION


MPEG 500, or Methoxy polyethylene glycol 500, is a chemical compound belonging to the class of polyethylene glycols (PEGs).
MPEG 500 (Methoxy polyethyleneglycol 500) is a polymer consisting of repeating ethylene oxide units with a molecular weight of around 500 Daltons.

MPEG 500 is commonly used in various industries, including pharmaceuticals, cosmetics, and industrial applications.
In pharmaceuticals, MPEG 500 (Methoxy polyethyleneglycol 500) can be found in formulations such as ointments, creams, and oral dosage forms, where it acts as a solubilizing agent, emulsifier, or viscosity modifier.
In cosmetics, MPEG 500 (Methoxy polyethyleneglycol 500) is used in products like creams, lotions, and shampoos for its moisturizing and emulsifying properties.

In industrial applications, MPEG 500 can be used as a lubricant, a surfactant, or a component in adhesives and coatings.
MPEG 500 is valued for its versatility, biocompatibility, and ability to improve the solubility and stability of various substances in formulations.

MPEG 500 (Methoxy polyethyleneglycol 500) is a water-soluble polymer with a molecular weight of approximately 500 Daltons.
MPEG 500 (Methoxy polyethyleneglycol 500) is commonly used in pharmaceutical formulations as a solubilizing agent and viscosity modifier.

MPEG 500 (Methoxy polyethyleneglycol 500) is characterized by its clear, colorless appearance and low viscosity.
MPEG 500 (Methoxy polyethyleneglycol 500) exhibits excellent compatibility with a wide range of active pharmaceutical ingredients.

Due to its amphiphilic nature, it acts as an effective emulsifier in cosmetic products.
When incorporated into creams and lotions, it imparts a smooth, non-greasy texture.



PROPERTIES


Physical Properties:

Appearance: Clear, colorless liquid
Odor: Odorless
Molecular Weight: Approximately 500 g/mol
Melting Point: Below room temperature (liquid at room temperature)
Boiling Point: Typically above 100°C (dependent on purity and atmospheric pressure)
Density: Varies, typically around 1.1 g/cm³
Solubility: Soluble in water and many organic solvents
Viscosity: Moderate viscosity, dependent on concentration and temperature
Refractive Index: Typically around 1.45 (dependent on purity and temperature)
Flash Point: Not applicable (non-flammable)


Chemical Properties:

Chemical Formula: (C2H4O)n(CH4O)x
Chemical Structure: Linear polymer consisting of repeating ethylene oxide units with methoxy end-groups
Hydrophilicity: Highly hydrophilic due to the presence of ethylene oxide units
pH: Neutral (approximately 7)
Stability: Chemically stable under normal conditions
Reactivity: Non-reactive under typical conditions, inert towards most chemicals
Biodegradability: Generally considered biocompatible and biodegradable
Toxicity: Low toxicity, considered safe for many applications
Flammability: Non-flammable
Compatibility: Compatible with a wide range of substances, including pharmaceuticals, cosmetics, and polymers.



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air.
If breathing is difficult, administer oxygen if available and trained to do so.
Seek medical attention if symptoms persist or worsen.


Skin Contact:

Remove contaminated clothing and rinse affected skin thoroughly with water.
Wash skin with mild soap and water.
Seek medical attention if irritation or redness persists.


Eye Contact:

Flush eyes with lukewarm water for at least 15 minutes, lifting the eyelids occasionally.
Seek immediate medical attention, even if irritation is mild or absent.


Ingestion:

Rinse mouth thoroughly with water.
Do not induce vomiting unless instructed to do so by medical personnel.
Seek immediate medical attention.
If the person is conscious, provide water or milk to dilute the substance if recommended by medical personnel.


General First Aid:

If any symptoms develop or persist after exposure, seek medical attention promptly.
Keep contaminated clothing and equipment away from other individuals.
Do not attempt to treat symptoms without professional medical advice.
Provide first aid responders with Safety Data Sheets (SDS) or other relevant information about the substance for proper treatment guidance.
Follow all safety precautions and guidelines provided by medical personnel or emergency responders.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate personal protective equipment (PPE), including safety glasses or goggles, gloves, and protective clothing, when handling Methoxy polyethylene glycol 500 to minimize skin and eye contact.

Ventilation:
Use adequate ventilation in areas where Methoxy polyethylene glycol 500 is handled to prevent the buildup of vapor or mist.
Ensure ventilation systems are in good working condition and provide sufficient airflow to minimize exposure.

Handling Precautions:
Avoid breathing vapors or mist generated from Methoxy polyethylene glycol 500.
Prevent skin and eye contact by wearing appropriate protective clothing and equipment.
Do not eat, drink, or smoke while handling the substance.
Wash hands thoroughly with soap and water after handling Methoxy polyethylene glycol 500.

Spill and Leak Procedures:
In case of a spill, contain the spill immediately to prevent spreading.
Absorb spilled material with inert absorbent material (e.g., sand, vermiculite) and collect in a suitable container for disposal.
Clean contaminated surfaces thoroughly with water and detergent.

Fire and Explosion Hazards:
Methoxy polyethylene glycol 500 is non-flammable and not combustible under normal conditions.
However, avoid exposure to high temperatures or open flames as it may decompose and release hazardous vapors.


Storage:

Storage Conditions:
Store Methoxy polyethylene glycol 500 in a cool, dry, well-ventilated area away from direct sunlight and heat sources.
Keep containers tightly closed when not in use to prevent contamination and evaporation.
Store away from incompatible materials, such as strong oxidizing agents and acids.

Temperature Control:
Maintain storage temperature within the specified range (if any) to prevent degradation or changes in properties.
Avoid exposure to extreme temperatures, as it may affect the stability and performance of Methoxy polyethylene glycol 500.

Container Compatibility:
Use containers made of suitable materials, such as high-density polyethylene (HDPE) or glass, that are compatible with Methoxy polyethylene glycol 500.
Ensure containers are labeled properly with appropriate hazard warnings and handling instructions.

Avoid Contamination:
Prevent contamination of Methoxy polyethylene glycol 500 by keeping storage areas clean and free from dust, dirt, and other foreign materials.
Do not store or use near food, beverages, or animal feed to avoid accidental ingestion or contamination.

Handling Precautions:
Follow all safety precautions and guidelines provided by the manufacturer and regulatory agencies for safe handling and storage of Methoxy polyethylene glycol 500.
Keep storage areas well-marked and secure to prevent unauthorized access or tampering.
MPEG 550
Mpeg 550 is methoxy PEG-10-based plasticizer.
Mpeg 550 possesses lubricity & humectant properties and maintains wet-tack strength.


CAS Number: 9004-74-4
MDL number: MFCD00084416
Linear Formula: CH3O(CH2CH2O)nH
Classification: PEG / PPG, Ethoxylated compound, Glycol, Synthetic polymer


Mpeg 550 is a high molecular weight product that belongs to methoxy polyoxyethylene glycols.
Mpeg 550 is intended mainly for the construction industry.
Mpeg 550 with higher molecular weight is generally solid at room temperature.


Mpeg 550 denotes a methylated polyethylene glycol derivative with the linear formula: CH3O(CH2CH2O)nH.
Mpeg 550 provides enhanced solvency, lubricity, hygroscopicity and with slightly more hydrophobic solvent properties.
Mpeg 550 is a mono-functional methoxylated PEG (550) methacrylate monomer that features excellent wetting, water solubility, low Tg, and fast surface cure.


Mpeg 550 possesses lubricity and humectant properties.
Mpeg 550 maintains wet-tack strength.
Mpeg 550 possesses lubricity & humectant properties and maintains wet-tack strength.


Mpeg 550 is methoxy PEG-10-based plasticizer.
Mpeg 550 is a white compact paste or solid.
Mpeg 550 is a polymer with high solubility in water and a slight odour.
The active substance content in Mpeg 550 is about 100%.


The number after "PEG-" indicates the average number of molecular units -CH2-CH2-O-, for Methoxy PEG-10 this is 10 molecular units.
Methoxy PEG derivatives are used in numerous cosmetic formulations mainly as moisturizers.
"Methoxy" refers to a methyl-oxygen group (CH3-O-).


Dimethoxy-, trimethoxy- etc refer to two, three or more methoxy groups.
"PEG" refers to a PEG-(polyethylene glycol-) derivative.
The number behind "PEG-" (or the first number behind "PEG/...-") refers to the average number of molecular units -CH2-CH2-O-.



USES and APPLICATIONS of MPEG 550:
Mpeg 550 is used in pressure-sensitive and thermoplastic adhesives.
Mpeg 550 has good water solubility, wettability, lubricity, physiological inertia, no stimulation to human body, and is widely used in cosmetics and pharmaceutical industry.


The viscosity, hygroscopicity and structure of the products can be changed by selecting products with different molecular weight.
Products with relatively low molecular weight (molecular weight less than 2000) are suitable for wetting agents and consistency regulators for cream, lotion, toothpaste, and cream.


The products with relatively high molecular weight are suitable for lipstick, deodorant stick, soap, pick up soap, foundation and cosmetics.
As a cleaning agent, Mpeg 550 is also used as suspending agent and thickener.
In the pharmaceutical industry, Mpeg 550 is used as the matrix of ointment, emulsion, ointment, lotion and suppository.


Mpeg 550 is used Adhesives-PSA, Adhesives-Waterborne, Emulsions, Paint & Coatings-Waterborne, Protective Coatings, and Water Soluble Resins
Mpeg 550 is used Rubber & Elastomers, Food Processing, Packaging, Textiles, Household Products, and Wood Processing.
Mpeg 550 is used Paper & Paper Products, Cosmetics & Personal Care, Pharmaceuticals, Electronics, Printing & Inks, andElectroplating / Electropolishing.


Mpeg 550 is used Adhesives, Lubricants, Agriculture, Metalworking, Ceramics, Paints & Coatings, and Chemical Intermediates.
Mpeg 550 provides enhanced solvency, lubricity, hygroscopicity and with slightly more hydrophobic solvent properties.
Mpeg 550 is used for use in adhesives, chemical intermediates, inks and dye carrier, lubricants, and soaps and detergents.


Mpeg 550 is used for use in adhesives, chemical intermediates, and lubricants.
Cosmetic Uses of Mpeg 550: humectants
Mpeg 550 is used in pressure sensitive and thermoplastic adhesives.


Mpeg 550 is recommended as a versatile intermediate for coatings and polymer modification.
Mpeg 550 is used in pressure sensitive adhesives and in thermoplastic adhesives.
Mpeg 550 can be used in the commercial concrete with high performance and high strength (above C60) which is mixed on site and transported remotely.


Mpeg 550 is soluble in water, ethanol and organic solvent.
Low steam pressure, stable for heat, Mpeg 550 is used as thickener and lubricant in textile printing and dyeing industry and daily chemical industry.
Mpeg 550 also reacts with acrylic acid to make MPEG acrylic acid ester, which is the main raw material for the preparation of polycarboxylate superplasticizer.


Mpeg 550 is mainly used for the production of polycarboxylate ether (PCE) superplasticizers for concrete.
Mpeg 550 is used in esterification reactions, e.g. with methacrylic acid which is further subjected to a polymerization process.
The resulting products are the main components of concrete admixtures that reduce the amount of batch water in cement concrete.


Mpeg 550 is used in pressure sensitive and thermoplastic adhesives.
Comb polymers, resulting from emulsion polymerization using Mpeg 550, are used in paint and varnish production.
They are dispersants for organic and inorganic pigments.


Mpeg 550 is used in various applications such as micelles for drug delivery as well as in modifications of therapeutic proteins to improve their pharmacokinetics.
Mpeg 550 is used in a wide range of lubricant applications due to their low volatility, solubility in water, and natural lubricity.
Mpeg 550 is non-staining to metal parts, textiles, and clothing and can be burned away leaving minimal residue.


-Application of Mpeg 550:
*the intermediate is used in the synthesis of superplasticizers (concrete admixtures),
*the intermediate is used in the synthesis of pigment dispersants.


-Markets and applications of Mpeg 550:
*Building & Construction
*Concrete & mortar additives


-Applications of Mpeg 550:
*Adhesives
*Chemical Intermediates
*Inks and Dye Carrier
*Lubricants
*Plasticizer
*Soaps and Detergents


-Uses of Mpeg 550:
*Adhesives
*Chemical intermediates
*Inks and dye carrier
*Lubricants
*Soaps and detergents



FUNCTIONS OF MPEG 550:
*Humectant :
Mpeg 550 maintains water content of a cosmetic both in its packaging and on the skin
Mpeg 550 holds and retains moisture in cosmetic products
*Solvent :
Mpeg 550 dissolves other substances
*Hydrophilicity
*Water Soluble
*Plasticizers
*Superplasticizers
*Composition
*Methoxy polyethylene glycols
*Segment
*Specialty Products / Specialty additives
*Surfactants / Non-ionic surfactants



PROPERTIES AND APPLICATIONS OF MPEG 550:
1. Applied in building materials industry, as the raw material of cement water-reducing agent, reinforcing agent.
The synthetic polycarboxylate superplasticizer of the material has strong ability of cement particle dispersion, thereof, the product is characterized of low dosage, high water-reducing rate, excellent reinforce effect, good durability, not corrosive to rebar and environmentally friendly.
Can be applied in high-performance and high strength (above C60) commodity concrete for on site agitation and long distance conveying.

2. Mpeg 550 is soluble in water, ethanol and organic solvents.
Mpeg 550 is used as thickener and lubricant in the textile printing and dyeing industry and daily chemical industry due to its low vapor pressure and thermal stability.



ADVANTAGES OF MPEG 550:
*effective component of PCE type superplasticizing admixtures, very good hygroscopic properties,
*low diol content,
*paste/soft wax consistency,
*high solubility in water,
*slight odour.



FEATURES OF MPEG 550:
If the refined raw material and special catalyst are used, the impurity content of the product is low.
And the hydroxyl activity at the end of the molecular chain is retained to the greatest extent, with good hydrophilicity and hydroxyl reaction activity.
Mpeg 550 with higher molecular weight are generally solid at room temperature.



METHOXYPOLYETHYLENE GLYCOLS (MPEG):
Methoxypolyethylene Glycols (MPEG) are used in pharmacology and cosmetics production; detergent & household goods production (as soap bars glue, soluble agent in detergent pastes, fixing agent for odors in soaps and detergents, as additive in general cleaners, polishers, air fresheners, automatic dishwashing detergents); in production of textile supporting substances (as component of dispergators and protective solutions); in metal works industry (as agents for cleaning and polishing pastes, lubricating & cooling liquids).



PHYSICAL and CHEMICAL PROPERTIES of MPEG 550:
Acidity (as acrylic acid): 0.01% MAX
Color (APHA): 50 MAX
Saponification Value (mg KOH/g): 82 MIN
Appearance Form: Crystalline solid or semi-solid
Odour: No data available
Odour Threshold: No data available
pH: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flash point: Not applicable
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapour pressure: No data available
Vapour density: No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient: noctanol/water
Auto-ignition temperature: No data available
Decomposition temperature: No data available
Viscosity: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available



FIRST AID MEASURES of MPEG 550:
-Description of first aid measures:
*General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of MPEG 550:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of MPEG 550:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of MPEG 550:
-Control parameters:
--Exposure controls:
-Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
--Personal protective equipment:
*Eye/face protection:
Safety glasses with side-shields.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of MPEG 550:
-Conditions for safe storage, including any incompatibilities:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of MPEG 550:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
Methoxy polyethylene glycol 550
MPEG-550
CAS 9004-74-4.
Methoxy Polyethylene Glycol
methoxy polyethylene glycol methacrylate 550
Methoxypolyethylene glycols 550



MPEG 750
Mpeg 750 is a methoxy PEG-16-based plasticizer.
Mpeg 750 has lubricating and moisturizing properties.
Mpeg 750 retains tack in wet conditions.


CAS Number: 9004-74-4
Linear Formula: CH3O(CH2CH2O)nH
MDL number: MFCD00084416
Classification: PEG / PPG, Ethoxylated compound, Glycol, Synthetic polymer


Mpeg 750 denotes a methylated polyethylene glycol derivative with the linear formula: CH3O(CH2CH2O)nH.
Mpeg 750 provides enhanced solvency, lubricity, hygroscopicity and with slightly more hydrophobic solvent properties.
Mpeg 750 is a mono-functional methoxylated PEG (550) methacrylate monomer that features excellent wetting, water solubility, low Tg, and fast surface cure.


Mpeg 750 possesses lubricity and humectant properties.
Mpeg 750 maintains wet-tack strength.
Mpeg 750 is a high molecular weight product that belongs to methoxy polyoxyethylene glycols.


Mpeg 750 is intended mainly for the construction industry.
Mpeg 750 with higher molecular weight is generally solid at room temperature.
Mpeg 750 is methoxy PEG-16-based plasticizer.


Mpeg 750 is a white compact paste or solid.
Mpeg 750 is a polymer with high solubility in water and a slight odour.
The active substance content in Mpeg 750 is about 100%.
The average molecular weight of Mpeg 750 is 750 g/mol.


The number after "PEG-" indicates the average number of molecular units -CH2-CH2-O-, for Methoxy PEG-10 this is 10 molecular units.
Methoxy PEG derivatives are used in numerous cosmetic formulations mainly as moisturizers.
"Methoxy" refers to a methyl-oxygen group (CH3-O-).


Dimethoxy-, trimethoxy- etc refer to two, three or more methoxy groups.
"PEG" refers to a PEG-(polyethylene glycol-) derivative.
The number behind "PEG-" (or the first number behind "PEG/...-") refers to the average number of molecular units -CH2-CH2-O-.



USES and APPLICATIONS of MPEG 750:
Products with relatively low molecular weight (molecular weight less than 2000) are suitable for wetting agents and consistency regulators for cream, lotion, toothpaste, and cream.
The products with relatively high molecular weight are suitable for lipstick, deodorant stick, soap, pick up soap, foundation and cosmetics.


As a cleaning agent, Mpeg 750 is also used as suspending agent and thickener.
In the pharmaceutical industry, Mpeg 750 is used as the matrix of ointment, emulsion, ointment, lotion and suppository.
Mpeg 750 also reacts with acrylic acid to make MPEG acrylic acid ester, which is the main raw material for the preparation of polycarboxylate superplasticizer.


Mpeg 750 is mainly used for the production of polycarboxylate ether (PCE) superplasticizers for concrete.
Mpeg 750 is used in esterification reactions, e.g. with methacrylic acid which is further subjected to a polymerization process.
Mpeg 750 can be used in the commercial concrete with high performance and high strength (above C60) which is mixed on site and transported remotely.


Mpeg 750 is soluble in water, ethanol and organic solvent.
Low steam pressure, stable for heat, Mpeg 750 is used as thickener and lubricant in textile printing and dyeing industry and daily chemical industry.
The resulting products are the main components of concrete admixtures that reduce the amount of batch water in cement concrete.


Mpeg 750 is used in pressure sensitive and thermoplastic adhesives.
Comb polymers, resulting from emulsion polymerization using Mpeg 750, are used in paint and varnish production.
They are dispersants for organic and inorganic pigments.


Mpeg 750 is used Adhesives-PSA, Adhesives-Waterborne, Emulsions, Paint & Coatings-Waterborne, Protective Coatings, and Water Soluble Resins
Mpeg 750 is used Rubber & Elastomers, Food Processing, Packaging, Textiles, Household Products, and Wood Processing.
Mpeg 750 is used Paper & Paper Products, Cosmetics & Personal Care, Pharmaceuticals, Electronics, Printing & Inks, andElectroplating / Electropolishing.


Mpeg 750 is used Adhesives, Lubricants, Agriculture, Metalworking, Ceramics, Paints & Coatings, and Chemical Intermediates.
Mpeg 750 provides enhanced solvency, lubricity, hygroscopicity and with slightly more hydrophobic solvent properties.
Mpeg 750 is used for use in adhesives, chemical intermediates, inks and dye carrier, lubricants, and soaps and detergents.


Mpeg 750 is used for use in adhesives, chemical intermediates, and lubricants.
Cosmetic Uses of Mpeg 750: humectants
Mpeg 750 is used in pressure-sensitive and thermoplastic adhesives.


Mpeg 750 is used in various applications such as micelles for drug delivery as well as in modifications of therapeutic proteins to improve their pharmacokinetics.
Mpeg 750 is used in a wide range of lubricant applications due to their low volatility, solubility in water, and natural lubricity.


Mpeg 750 is non-staining to metal parts, textiles, and clothing and can be burned away leaving minimal residue.
Mpeg 750 is used in pressure sensitive and thermoplastic adhesives.
Mpeg 750 is recommended as a versatile intermediate for coatings and polymer modification.


Mpeg 750 is used in pressure sensitive adhesives and in thermoplastic adhesives.
Mpeg 750 has good water solubility, wettability, lubricity, physiological inertia, no stimulation to human body, and is widely used in cosmetics and pharmaceutical industry.
The viscosity, hygroscopicity and structure of the products can be changed by selecting products with different molecular weight.


-Application of Mpeg 750:
*the intermediate is used in the synthesis of superplasticizers (concrete admixtures),
*the intermediate is used in the synthesis of pigment dispersants.


-Markets and applications of Mpeg 750:
*Building & Construction
*Concrete & mortar additives


-Applications of Mpeg 750:
*Adhesives
*Chemical Intermediates
*Inks and Dye Carrier
*Lubricants
*Plasticizer
*Soaps and Detergents


-Uses of Mpeg 750:
*Adhesives
*Chemical intermediates
*Inks and dye carrier
*Lubricants
*Soaps and detergents



FUNCTIONS OF MPEG 750:
*Humectant :
Mpeg 750 maintains water content of a cosmetic both in its packaging and on the skin
Mpeg 750 holds and retains moisture in cosmetic products
*Solvent :
Mpeg 750 dissolves other substances
*Hydrophilicity
*Water Soluble
*Plasticizers
*Superplasticizers
*Composition
*Methoxy polyethylene glycols
*Segment
*Specialty Products / Specialty additives
*Surfactants / Non-ionic surfactants



PROPERTIES AND APPLICATIONS OF MPEG 750:
1. Applied in building materials industry, as the raw material of cement water-reducing agent, reinforcing agent.
The synthetic polycarboxylate superplasticizer of the material has strong ability of cement particle dispersion, thereof, the product is characterized of low dosage, high water-reducing rate, excellent reinforce effect, good durability, not corrosive to rebar and environmentally friendly.
Can be applied in high-performance and high strength (above C60) commodity concrete for on site agitation and long distance conveying.

2. Mpeg 750 is soluble in water, ethanol and organic solvents.
Mpeg 750 is used as thickener and lubricant in the textile printing and dyeing industry and daily chemical industry due to its low vapor pressure and thermal stability.



ADVANTAGES OF MPEG 750:
*effective component of PCE type superplasticizing admixtures, very good hygroscopic properties,
*low diol content,
*paste/soft wax consistency,
*high solubility in water,
*slight odour.



FEATURES OF MPEG 750:
If the refined raw material and special catalyst are used, the impurity content of the product is low.
And the hydroxyl activity at the end of the molecular chain is retained to the greatest extent, with good hydrophilicity and hydroxyl reaction activity.
Mpeg 750 with higher molecular weight are generally solid at room temperature.



METHOXYPOLYETHYLENE GLYCOLS (MPEG)
Methoxypolyethylene Glycols (MPEG) are used in pharmacology and cosmetics production; detergent & household goods production (as soap bars glue, soluble agent in detergent pastes, fixing agent for odors in soaps and detergents, as additive in general cleaners, polishers, air fresheners, automatic dishwashing detergents); in production of textile supporting substances (as component of dispergators and protective solutions); in metal works industry (as agents for cleaning and polishing pastes, lubricating & cooling liquids).



PHYSICAL and CHEMICAL PROPERTIES of MPEG 750:
Moleculer Weight: 700-800
Appearance Form: Crystalline solid or semi-solid
Odour: No data available
Odour Threshold: No data available
pH: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flash point: Not applicable
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapour pressure: No data available
Vapour density: No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient: noctanol/water
Auto-ignition temperature: No data available
Decomposition temperature: No data available
Viscosity: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available



FIRST AID MEASURES of MPEG 750:
-Description of first aid measures:
*General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of MPEG 750:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of MPEG 750:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of MPEG 750:
-Control parameters:
--Exposure controls:
-Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
--Personal protective equipment:
*Eye/face protection:
Safety glasses with side-shields.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of MPEG 750:
-Conditions for safe storage, including any incompatibilities:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of MPEG 750:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
Methoxy polyethylene glycol
MPEG
METHOXY PEG-17
(Methoxy polyethylene glycol)
CAS 9004-74-4.
Methoxy Polyethylene Glycol
methoxy polyethylene glycol methacrylate 750
Methoxypolyethylene glycols 750
mPEG-alkyne
poly(ethylene glycol)methyl ether acetylene
mPEG-acetylene

MPG (MONOPROPYLENE GLYCOL)
MPG (Monopropylene glycol) is racemate is a hygroscopic viscous liquid and is slightly spicy.
MPG (Monopropylene glycol) is miscible with water, acetone, ethyl acetate and chloroform, and is soluble in ether.
MPG (Monopropylene glycol) is soluble in many essential oils, but is not miscible with petroleum ether and paraffin oil.

CAS Number: 57-55-6
Molecular Formula: C3H8O2
Molecular Weight: 76.09
EINECS Number: 200-338-0

Synonyms: propylene glycol, 1,2-propanediol, propane-1,2-diol, 57-55-6, 1,2-Propylene glycol, 1,2-dihydroxypropane, 2-Hydroxypropanol, Isopropylene glycol, Methylethyl glycol, Methylethylene glycol, Monopropylene glycol, Dowfrost, Sirlene, Trimethyl glycol, 2,3-Propanediol, Propylene Glycol USP, Solargard P, alpha-Propyleneglycol, Solar Winter BAN, dl-Propylene glycol, DL-1,2-Propanediol, Methyl glycol, Ucar 35, 1,2-Propylenglykol, (RS)-1,2-Propanediol, Sentry Propylene Glycol, PG 12, FEMA No. 2940, (+-)-1,2-Propanediol, Kilfrost ABC-S, (+-)-Propylene glycol, Caswell No. 713, General lube, Kollisolv pg, CCRIS 5929, HSDB 174, 1,2 Propanediol, All purpose lubricant, AI3-01898, alpha-Propylene glycol, 1,2-Propylenglykol [German], NSC 69860, HOCH2CH(OH)Me, MeCH(OH)CH2OH, EPA Pesticide Chemical Code 068603, CHEBI:16997, Propyleneglycolum, .alpha.-Propylene glycol, CH3CH(OH)CH2OH, HOCH2CH(OH)CH3, 1,2-(RS)-Propanediol, propylene glycerol, Propylene glycol (solvent), 1,2-propandiol, EINECS 200-338-0, (+/-)-1,2-propanediol, 1000PG, NSC-69860, SDM No. 27, 1,2-propane-diol, Ins-1520, UNII-6DC9Q167V3, BRN 1340498, L-1,2-propanediol, DTXSID0021206, PROPANEDIOL-, 6DC9Q167V3, Propylene glycol dl-form, S-(+)-Propylene glycol, MFCD00064272, Ins no.1520, 123120-98-9, propylenglycol, Propylene glycol [USP
], DTXCID901206, 1,2-Propanediol (8CI,9CI), 1,2-PDO, E-1520, EC 200-338-0, (2RS)-PROPANE-1,2-DIOL, NSC69860, Poly(propylene glycol) average Mn 400, NCGC00090739-02, Poly(propylene glycol) average Mn 2000, Poly(propylene glycol) average Mn 4000, ( inverted exclamation markA)-1,2-Propanediol, Prolugen, Propylene glycol (USP
), PROPYLENE GLYCOL (II), PROPYLENE GLYCOL [II], propylene-glycol, C3H8O2, Propan-1,2-Diol, Ilexan P, PROPYLENE GLYCOL (MART.), PROPYLENE GLYCOL [MART.], PROPYLENE GLYCOL (USP-RS), PROPYLENE GLYCOL [USP-RS], 1,2-(RS)-Propanediol; 1,2-Dihydroxypropane; 1,2-Propylene glycol, PROPYLENE GLYCOL (EP MONOGRAPH), PROPYLENE GLYCOL [EP MONOGRAPH], Glycol, Propylene, CAS-57-55-6, PROPYLENE GLYCOL (USP MONOGRAPH), PROPYLENE GLYCOL [USP MONOGRAPH], 63625-56-9, GLYCEROL IMPURITY C (EP IMPURITY), GLYCEROL IMPURITY C [EP IMPURITY], 1,2-propane diol, ()-1,2-propanediol, (S)-(+)-Propylene glycerol, Propilenoglicol, Propylenglykol, Propylenglycolum, Systane Balance, Metiletilenglicol, Propyleeniglykoli, Vet Lube, Glicol propilenico, Glikol propylenowy, 1-2-propanediol, 1.2-propanediol, OB Lube, 2-Dihydroxypropanol, Propylene glycol; (RS)-propane-1,2-diol; Glycerol Imp. C (EP); GR 43314X; Glycerol Impurity C, Systane COMPLETE, 1,2 -propanediol, Lubiseptol Lubricant, 1,2-Hydroxypropane, 1,2-propyleneglycol, Propylene Glycol (Propane-1,2-diol), Propane-1,2-glycol, LS-1391

MPG (Monopropylene glycol) is scientifically named as “1,2-propanediol”, and has a chemical formula of CH3CHOHCH2OH and a molecular weight of 76.10.
MPG (Monopropylene glycol) has a specific gravity of 1.036 (25/4 °C), a freezing point of-59 °C, and a boiling point of 188.2 °C, respectively 83.2 °C (1,333 Pa).

MPG (Monopropylene glycol) is relatively stable to heat and light, and is more stable at low temperatures.
Its L-isomer has a boiling point of 187 to 189 °C and a specific optical rotation [α] of D20-15.0°.
MPG (Monopropylene glycol) can be oxidized at high temperatures to propionaldehyde, lactic acid, pyruvic acid and acetic acid.

MPG (Monopropylene glycol) is a diol having the general nature of the alcohol.
It can react with inorganic and organic acids to generate mono-or di-esters.
MPG (Monopropylene glycol) reacts with propylene oxide to generate ether, with hydrogen halide to generate halohydrin, and with acetaldehyde to generate methyl dioxolane.

MPG (Monopropylene glycol) is a clear, colourless and viscous liquid with a characteristic odour and has the formula C3H8O2.
This solvent is soluble in water and holds hygroscopic properties, meaning it can attract hard water molecules.
MPG (Monopropylene glycol) is a viscous, colorless liquid, which is nearly odorless but possesses a faintly sweet taste.

Its chemical formula is CH3CH(OH)CH2OH.
As it contains two alcohol groups, it is classed as a diol.
MPG (Monopropylene glycol) is miscible with a broad range of solvents, including water, acetone, and chloroform.

In general, glycols are non-irritating and have very low volatility.
MPG (Monopropylene glycol) is produced on a large scale primarily for the production of polymers.
In the European Union, it has E-number E1520 for food applications.

For cosmetics and pharmacology, the number is E490.
MPG (Monopropylene glycol) is also present in propylene glycol alginate, which is known as E405.
MPG (Monopropylene glycol) is a compound which is GRAS (generally recognized as safe) by the US Food and Drug Administration under 21 CFR x184.1666, and is also approved by the FDA for certain uses as an indirect food additive.

MPG (Monopropylene glycol) is approved and used as a vehicle for topical, oral, and some intravenous pharmaceutical preparations in the U.S. and in Europe.
MPG (Monopropylene glycol) is sometimes called (alpha) α-propylene glycol to distinguish it from the isomer propane-1,3-diol, known as (beta) β-propylene glycol.
MPG (Monopropylene glycol) is chiral.

Commercial processes typically use the racemate.
The S-isomer is produced by biotechnological routes.
MPG (Monopropylene glycol) is used as a solvent and carrier in pharmaceutical formulations such as oral liquids, creams, and lotions.

MPG (Monopropylene glycol) helps dissolve active ingredients and improve the stability of the formulation.
MPG (Monopropylene glycol) is used as a food additive, particularly in products where it functions as a humectant, preservative, or solvent.
MPG (Monopropylene glycol) is considered safe for use in food and is often found in processed foods, beverages, and food flavorings.

MPG (Monopropylene glycol) is a common ingredient in cosmetics, skin care products, and personal care items such as lotions, shampoos, and deodorants.
It helps to maintain moisture, improve texture, and stabilize formulations.
Due to its low freezing point and high boiling point, monopropylene glycol is used as an antifreeze agent in automotive coolant formulations and as a heat transfer fluid in industrial applications.

MPG (Monopropylene glycol) serves as a precursor in the production of various chemicals, including unsaturated polyester resins, plasticizers, and polyurethanes.
MPG (Monopropylene glycol) is sometimes used in deicing solutions to melt ice on aircraft, runways, and roads during winter months.
MPG (Monopropylene glycol) has good solubility and less toxicity and irritation, and is widely used as solvents, extraction solvents and preservatives for injections (eg. intramuscular injections, intravenous injections) and non-injectable pharmaceutical preparations (such as oral liquid, ophthalmic preparations, otic preparations, dental preparations, rectovaginal preparations, transdermal preparations, etc.).

MPG (Monopropylene glycol) is better than glycerol solvent and can dissolve many substances such as corticosteroids (sex hormone), chloramphenicol, sulfonamides, barbiturate, reserpine, quinidine, corticosterone acetate, tetrahydropalmatine sulfate, mechlorethamine hydrochloride, vitamin A, vitamin D, many volatile oils, most of the alkaloids and many local anesthetics.
MPG (Monopropylene glycol) is similar to ethanol when used as a bacteriostatic agent, and its efficacy to inhibit mold is similar to glycerin and is slightly lower than that of ethanol.

MPG (Monopropylene glycol) is commonly used as a plasticizer for the aqueous film coating materials.
Its mixture with equal amounts of water can delay the hydrolysis of certain drugs, and increase the stability of the preparation product.
MPG (Monopropylene glycol) is used as an antimicrobial preservative in 15% to 30% propylene glycol solution and semi-solid formulation, as humectants in about 15% propylene glycol topical formulation, and as solvent and co-solvent in 10% to 30% propylene glycol aerosol solvent, 10% to 25 % propylene glycol oral solution, 10% to 60% injectable formulation and 5% to 80% topical formulation.

MPG (Monopropylene glycol) is very stable at room temperature, but is oxidized when left open at high temperatures (above 280 °C); has a chemical stability after mixing with 95% ethanol or water; can be sterilized by autoclaving or sterile filtration.
MPG (Monopropylene glycol) has hygroscopicity, and should be positioned at cool and dry place and stored in dark airtight container.
The filler is polyethylene glycol 20M (Carbowax compound 20M) 4%, and the carrier is a 40/60 mesh sieved polytetrafluoroethylene (Chromosorb T) or similar material.

MPG (Monopropylene glycol) and water are fed in a molar ratio of 1: 15, and react at 150-2000 °C, a pressure of 1.2-1.4 MPa for 30 minutes to obtain 16% aqueous solution of propylene glycol, which is subjected to evaporation to obtain the finished product.
The reaction is performed under catalyzation of sulfuric acid or hydrochloric acid.
MPG (Monopropylene glycol) is added into 10% to 15% aqueous solution of propylene oxide, the mixture is hydrolyzed at 50 to 70 °C; the hydrolysate is neutralized and concentrated under reduced pressure, and refined to obtain the finished products.

The preparation method is a method in which propylene oxide is hydrolyzed to propylene glycol, and which can be carried out in the liquid phase.
There are catalytic and non-catalytic processes in industry.
MPG (Monopropylene glycol) is a method in which hydrolysis is carried out in the presence of 0.5% to 1% sulfuric acid at 50 to 70 °C.

Non-catalytic process is carried out under high temperature and pressure (150 to 300℃, 980 to 2940kPa), and is used for production in domestic.
Industrially, MPG (Monopropylene glycol) is mainly produced from propylene oxide (for food-grade use).
According to a 2018 source, 2.16 M tonnes are produced annually.

Manufacturers use either non-catalytic high-temperature process at 200 °C (392 °F) to 220 °C (428 °F), or a catalytic method, which proceeds at 150 °C (302 °F) to 180 °C (356 °F) in the presence of ion exchange resin or a small amount of sulfuric acid or alkali.
Final products contain 20% propylene glycol, 1.5% of dipropylene glycol, and small amounts of other polypropylene glycols.
Further purification produces finished industrial grade or USP/JP/EP/BP grade propylene glycol that is typically 99.5% or greater.

Use of USP (US Pharmacopoeia) MPG (Monopropylene glycol) can reduce the risk of Abbreviated New Drug Application (ANDA) rejection.
MPG (Monopropylene glycol) can also be obtained from glycerol, a byproduct from the production of biodiesel.
This starting material is usually reserved for industrial use because of the noticeable odor and taste that accompanies the final MPG (Monopropylene glycol).

MPG (Monopropylene glycol) may be non-irritating to the skin, see section Allergic reaction below for details on allergic reactions.
Undiluted propylene glycol is minimally irritating to the eye, producing slight transient conjunctivitis; the eye recovers after the exposure is removed.
A 2018 human volunteer study found that 10 male and female subjects undergoing 4 hours exposures to concentrations of up to 442 mg/m3 and 30 minutes exposures to concentrations of up to 871 mg/m3 in combination with moderate exercise did not show pulmonary function deficits, or signs of ocular irritation, with only slight symptoms of respiratory irritation reported.

MPG (Monopropylene glycol) has not caused sensitization or carcinogenicity in laboratory animal studies, nor has it demonstrated genotoxic potential.
MPG (Monopropylene glycol) is produced from propylene oxide. The most common process is by the non-catalytic hydrolysis of propylene oxide in a high-temperature and high-pressure environment. The second method is the catalytic one, which can proceed at 150 °C, in the presence of ion exchange resin, or a small amount of sulphuric acid or alkali.

MPG (Monopropylene glycol) can also be produced from glycerol which is a bio-diesel by-product.
The demand for, and consumption of, MPG (Monopropylene glycol) is high with an estimated 1.2 million tonnes produced yearly by plants situated around the world.
MPG (Monopropylene glycol) is a high-performance heat transfer fluid designed for use in indirect cooling in domestic, commercial, and industrial cooling applications.

MPG (Monopropylene glycol) is an antifreeze which is a clear, odourless and slightly viscous liquid.
MPG (Monopropylene glycol) is non-hazardous, food-safe and used in a huge variety of situations.
MPG (Monopropylene glycol) is a clear, odourless and slightly viscous liquid which has a huge variety of uses due to its heat transfer properties and non-hazardous nature.

MPG (Monopropylene glycol) is a clear, colourless, and viscous liquid organic compound with the chemical formula C3H8O2.
MPG (Monopropylene glycol) is a type of glycol, which is a family of compounds that contains two hydroxyl (-OH) groups.
MPG (Monopropylene glycol) is also known as 1,2-propanediol.

MPG (Monopropylene glycol) is a versatile chemical that is used in a wide range of applications.
One of its most common applications is as a humectant, which means it helps to retain moisture in products.
MPG (Monopropylene glycol) is used as a humectant in personal care and cosmetic products, such as lotions, creams, and hair conditioners.

MPG (Monopropylene glycol) is also used as a solvent in various industries, such as the pharmaceutical industry, where it is used to dissolve active pharmaceutical ingredients (APIs) and in the food industry as a solvent for flavourings and colourings.
MPG (Monopropylene glycol) is also used as a solvent for fragrances, inks, and dyes.
MPG (Monopropylene glycol) is a clear, colourless and viscous liquid with a very characteristic odour.

It is a type of solvent that is soluble in water and it also holds hygroscopic properties, which in simple terms, means it has the ability to attract had water molecules and can hold onto them.
MPG (Monopropylene glycol) is used widely in a range of industries as it has a low toxicity, not only this but it has a freezing point that is triggered when mixed with water.
MPG (Monopropylene glycol) has the ability to attract and retain moisture from the surrounding environment, making it useful as a humectant in various products such as cosmetics, pharmaceuticals, and food.

MPG (Monopropylene glycol) serves as a versatile solvent and diluent in many formulations, aiding in the dissolution of various active ingredients, flavors, and fragrances.
Its miscibility with water and other solvents makes it valuable in numerous applications.
MPG (Monopropylene glycol) helps stabilize emulsions by preventing the separation of oil and water phases.

MPG (Monopropylene glycol) is often used in creams, lotions, and other emulsion-based products to maintain consistency and texture.
Due to its low freezing point and high boiling point, MPG (Monopropylene glycol) is commonly used as an antifreeze agent in automotive coolants, as well as in industrial heating and cooling systems.
It is approved for use as a food additive by regulatory agencies such as the FDA (U.S. Food and Drug Administration) and EFSA (European Food Safety Authority).

MPG (Monopropylene glycol) is used in food processing as a humectant, solvent, and preservative.
In pharmaceuticals, it is utilized as a solvent for oral and injectable medications, as well as a component of topical formulations such as gels and ointments.
MPG (Monopropylene glycol) is employed in deicing solutions for aircraft, runways, and roads to prevent ice formation during winter months.

MPG (Monopropylene glycol) is also used in antifreeze formulations for water-based systems.
MPG (Monopropylene glycol) serves as a starting material or intermediate in the synthesis of various organic compounds, including polyester resins, plasticizers, polyurethanes, and specialty chemicals.
MPG (Monopropylene glycol) is generally recognized as safe (GRAS) for use in food and pharmaceutical applications when used in accordance with applicable regulations and guidelines.

It is important to handle MPG (Monopropylene glycol) with proper precautions to avoid skin contact, ingestion, or inhalation of vapors.
Safety data sheets (SDS) and product labels should be consulted for specific safety information, handling instructions, and first aid measures.
Regulatory agencies such as the FDA, EPA (U.S. Environmental Protection Agency), and REACH (Registration, Evaluation, Authorization, and Restriction of Chemicals) in the EU regulate the use of MPG (Monopropylene glycol) in various applications to ensure safety and environmental compliance.

Melting point: -60 °C (lit.)
Boiling point: 187 °C (lit.)
Density: 1.036 g/mL at 25 °C (lit.)
vapor density: 2.62 (vs air)
vapor pressure: 0.08 mm Hg ( 20 °C)
refractive index: n20/D 1.432(lit.)
FEMA: 2940 | PROPYLENE GLYCOL
Flash point: 225 °F
storage temp.: Store at +5°C to +30°C.
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka: 14.49±0.20(Predicted)
form: Viscous Liquid
color: APHA: ≤10
Specific Gravity:1.038 (20/20℃)1.036~1.040
Odor: at 100.00 %. odorless very slight alcoholic
PH: 6-8 (100g/l, H2O, 20℃)
explosive limit 2.4-17.4%(V)
Odor Type: odorless
Water Solubility: miscible
Sensitive: Hygroscopic
Merck: 14,7855
JECFA Number: 925
BRN: 1340498
Dielectric constant: 32.0
InChIKey: DNIAPMSPPWPWGF-UHFFFAOYSA-N
LogP: -0.92

MPG (Monopropylene glycol) solution (40% to 60%, v/vCH2CH[OH]CH2OH, propylene glycol) applied to the skin under plastic occlusion hydrates the skin and causes desquamation of scales.
MPG (Monopropylene glycol), isotonic in 2% concentration, is a widely used vehicle in dermatologic preparations.
Hydroalcoholic gels containing MPG (Monopropylene glycol) or other substances augment the keratolytic action of salicylic acid.

MPG (Monopropylene glycol), and water and is an extremely effective keratolytic agent.
Overnight occlusion is used nightly until improvement is evident, at which time the frequency of therapy can be decreased to every third night or once weekly.
This therapy is well tolerated, is usually nonirritating, and has been most successful in patients with X-linked ichthyosis vulgaris.

Burning and stinging may occur when applied to damaged skin.
Patients with other abnormalities of keratinization with hyperkeratosis, scaling, and dryness may also benefit.
MPG (Monopropylene glycol) is a grade of propylene glycol used in various industrial and commercial applications.

MPG (Monopropylene glycol) is clear, colourless and viscous liquid with almost no odour but a subtly sweet taste.
MPG (Monopropylene glycol) is soluble in water and has hygroscopic (moisture absorbent) properties.
MPG (Monopropylene glycol) is a colourless liquid that is added to foods, moisturising creams, lotions, bath salts and any other formulations to add additional moisturisation.

MPG (Monopropylene glycol) is also added to skin and hair care products and soap making as a lubricant and preservative.
MPG (Monopropylene glycol), referring to the United States and European Pharmacopoeias, is a high-purity grade of monopropylene glycol for use in pharmaceutical, food, cosmetic, personal care, flavor and fragrance, plus a variety of other applications.
The clear, colorless, nearly odorless, slightly viscous, water-soluble and hygroscopic liquid with low vapor pressure is produced and handled in compliance with current Good Manufacturing Practice (cGMP) guidelines.

Forty-five percent of propylene glycol produced is used as a chemical feedstock for the production of unsaturated polyester resins.
In this regard, propylene glycol reacts with a mixture of unsaturated maleic anhydride and isophthalic acid to give a copolymer.
This partially unsaturated polymer undergoes further crosslinking to yield thermoset plastics.

Related to this application, MPG (Monopropylene glycol) reacts with propylene oxide to give oligomers and polymers that are used to produce polyurethanes.
MPG (Monopropylene glycol) is used in water-based acrylic architectural paints to extend dry time which it accomplishes by preventing the surface from drying due to its slower evaporation rate compared to water.
MPG (Monopropylene glycol) is also used in various edible items such as coffee-based drinks, liquid sweeteners, ice cream, whipped dairy products and soda.

Vaporizers used for delivery of pharmaceuticals or personal-care products often include propylene glycol among the ingredients.
In alcohol-based hand sanitizers, it is used as a humectant to prevent the skin from drying.
MPG (Monopropylene glycol) is used as a solvent in many pharmaceuticals, including oral, injectable, and topical formulations.

Many pharmaceutical drugs which are insoluble in water utilize MPG (Monopropylene glycol) as a solvent and carrier; benzodiazepine tablets are one example.
MPG (Monopropylene glycol) is also used as a solvent and carrier for many pharmaceutical capsule preparations.
Additionally, certain formulations of artificial tears use propylene glycol as an ingredient.

The freezing point of water is depressed when mixed with propylene glycol.
It is used as aircraft de-icing and anti-icing fluid.
A 50% water-diluted and heated solution is used for removal of icing accretions from the fuselages of commercial aircraft on the ground (de-icing), and 100% undiluted cold solution is used only on wings and tail surfaces of an aircraft in order to prevent ice accretion from forming during a specific period of time before takeoff (anti-icing).

Normally, such time-frame is limited to 15–90 minutes, depending on the severity of snowfall and outside air temperature.
Water-propylene glycol mixtures dyed pink to indicate the mixture is relatively nontoxic are sold under the name of RV or marine antifreeze.
MPG (Monopropylene glycol) is frequently used as a substitute for ethylene glycol in low toxicity, environmentally friendly automotive antifreeze.

MPG (Monopropylene glycol) is also used to winterize the plumbing systems in vacant structures.
The eutectic composition/temperature is 60:40 propylene glycol:water/−60 °C.
The −50 °F/−45 °C commercial product is, however, water rich; a typical formulation is 40:60.

Inhalation of propylene glycol vapors appears to present no significant hazard in ordinary applications.
Due to the lack of chronic inhalation data, it is recommended that propylene glycol not be used in inhalation applications such as theatrical productions, or antifreeze solutions for emergency eye wash stations.
Recently, propylene glycol (commonly alongside glycerol) has been included as a carrier for nicotine and other additives in e-cigarette liquids, the use of which presents a novel form of exposure.

The potential hazards of chronic inhalation of MPG (Monopropylene glycol) or the latter substance as a whole are as-yet unknown.
According to a 2010 study, the concentrations of PGEs (counted as the sum of MPG (Monopropylene glycol) and glycol ethers) in indoor air, particularly bedroom air, has been linked to increased risk of developing numerous respiratory and immune disorders in children, including asthma, hay fever, eczema, and allergies, with increased risk ranging from 50% to 180%.
This concentration has been linked to use of water-based paints and water-based system cleansers.

However, the study authors write that glycol ethers and not MPG (Monopropylene glycol) are the likely culprit.
MPG (Monopropylene glycol) is ideal for E-liquid, various food applications, floral waters, moisturising, hair, soap and skin care products.
MPG (Monopropylene glycol) can also aid the bonding of oils and blends so that they perfectly combine in food applications.

Due to it being a colourless liquid; this means it can be added to foods, moisturising creams, lotions, bath salts and your other formulations to add additional moisturisation and it is also added to skin and hair care products and soap making as a lubricant and preservative.
MPG (Monopropylene glycol) is a viscous, colourless and odourless organic liquid.
Also referred to as MPG (Monopropylene glycol), it carries the chemical formula C3H802 and has a number of uses across a variety of different industries and applications.

Monarch Chemicals are a leading UK supplier of MPG and can offer USP, Industrial and Feed grades.
MPG (Monopropylene glycol) has a minimum purity of 99.8%.
This grade has a wide number of uses across food, flavourings, pharmaceutical and personal care products.

MPG (Monopropylene glycol) is used as a ‘carrier’ in e-cigarette / vape products, delivering the flavour and providing a throat-hit which ex-smokers look for in vape products.
MPG (Monopropylene glycol) is also used as an emulsifier in cosmetics, humectant in foods and a plasticiser in personal care products such as hand gels and moisturising creams.
MPG (Monopropylene glycol), or simply called glycol, is a colorless organic substance, tasteless and odorless, widely used in various sectors of modern industry due to its hydrological properties, as well as for its status as a polyhydric alcohol and its ability to miscibility in water and other liquids such as acetone or chloroform.

MPG (Monopropylene glycol) is important to mention that this alcohol is obtained by hydration of propylene oxide, so it is a relatively easy substance to produce.
MPG (Monopropylene glycol) is possible to find two types of monopropylene glycol in the modern market: The technical grade for industrial use and monopropylene glycol USP, which is for human use.
There are a variety of uses for MPG (Monopropylene glycol), some companies even produce two grades of MPG (Monopropylene glycol) due to the high demand and also so they can supply for the vary of needs this product has.

The first grade is predominantly used in the food industry, mainly for food flavouring and food colouring.
MPG (Monopropylene glycol) is also a classified humectant food additive (E1520).
There are also many applications for this solvent in the beauty industry, particularly in personal hygiene products, such as bubble bath, shampoo, baby wipes and also moisturiser in makeup.

MPG (Monopropylene glycol) is a clear, colourless and fully miscible liquid.
MPG (Monopropylene glycol) has a low freezing point thus remains viscous at reduced temperatures.
Provides freezethaw stabilisation; acting as a coupling agent between water and other components when added to water-based systems and slurries.

Uses:
MPG (Monopropylene glycol) is used for similar applications as other glycols.
MPG (Monopropylene glycol) is an important raw material for unsaturated polyester, epoxy resin, and polyurethane resin.
The use amount in this area accounts for about 45% of the total consumption of propylene glycol.

Such unsaturated polyester is used extensively for reinforced plastics and surface coatings.
MPG (Monopropylene glycol) is excellent in viscosity and hygroscopicity and is non-toxic, and thus is widely used as hygroscopic agent, antifreeze, lubricants and solvents in the food, pharmaceutical and cosmetic industry.
In the food industry, MPG (Monopropylene glycol) reacts with fatty acid to give propylene ester of fatty acids, and is mainly used as food emulsifier; Propylene glycol is a good solvent for flavorings and pigments.

MPG (Monopropylene glycol) is commonly used as solvents, softeners and excipients, etc. in the pharmaceutical industry for the manufacture of various types of ointments and salves.
MPG (Monopropylene glycol) is also used as a solvent and a softener for cosmetic since it has good mutual solubility with various spices.
MPG (Monopropylene glycol) is also used as tobacco moisturizing agents, antifungal agents, food processing equipment lubricants and solvents for food marking ink.

Aqueous solution of propylene glycol is an effective anti-freeze agent.
MPG (Monopropylene glycol) is used as antifreeze in breweries and diaries, in the manufacture of resins, as a solvent, and as an emulsifier in food.
MPG (Monopropylene glycol) was present as an occupational sensitizer in the color-film developer Flexicolor.

MPG (Monopropylene glycol) is a humectant and flavor solvent that is a polyhy- dric alcohol (polyol).
MPG (Monopropylene glycol) is a clear, viscous liquid with complete solu- bility in water at 20°c and good oil solvency.
MPG (Monopropylene glycol) functions as a humectant, as do glycerol and sorbitol, in maintaining the desired moisture content and texture in foods such as shredded coconut and icings.

MPG (Monopropylene glycol) functions as a solvent for flavors and colors that are insoluble in water.
MPG (Monopropylene glycol) is also used in beverages and candy.
Next to water, MPG (Monopropylene glycol) is the most common moisturecarrying vehicle used in cosmetic formulations.

MPG (Monopropylene glycol) has better skin permeation than glycerin, and it also gives a pleasant feel with less greasiness than glycerin.
MPG (Monopropylene glycol) is used as a humectant because it absorbs water from the air.
MPG (Monopropylene glycol) also serves as a solvent for anti-oxidants and preservatives.

In addition, it has preservative properties against bacteria and fungi when used in concentrations of 16 percent or higher.
There is a concern that propylene glycol is an irritant at high concentrations, though it appears to be quite safe at usage levels under 5 percent.
MPG (Monopropylene glycol) is used across a wide range of industries as it has low toxicity, coupled with a freezing point which is depressed upon mixing with water.

MPG (Monopropylene glycol) is used in deicing fluids for aircraft to remove ice and frost from the surfaces of airplane wings, fuselage, and other critical components before takeoff.
MPG (Monopropylene glycol) helps prevent ice accumulation and ensures safe flying conditions during winter weather.
MPG (Monopropylene glycol) is added to building materials such as concrete, mortar, and grout to improve workability and reduce water evaporation, thereby enhancing moisture retention and curing efficiency.

MPG (Monopropylene glycol) is used as an antifreeze agent in radiant heating systems to prevent freezing of water or heat transfer fluids in pipes and radiators, ensuring continuous operation in cold climates.
MPG (Monopropylene glycol) is employed as a coolant and heat transfer fluid in electronic devices such as computers, servers, and power electronics to dissipate heat generated by electronic components, thereby preventing overheating and ensuring optimal performance.
MPG (Monopropylene glycol) is used as a hydraulic fluid in hydraulic systems and equipment to transmit power and control movement in various industrial and manufacturing processes.

MPG (Monopropylene glycol) is used as an antifreeze agent in marine engines and cooling systems to prevent freezing and corrosion of engine components, particularly in boats, yachts, and other marine vessels operating in cold climates.
MPG (Monopropylene glycol) is utilized in textile dyeing and finishing processes as a solvent and wetting agent to facilitate dye penetration, improve color fastness, and enhance fabric softness and handle.
MPG (Monopropylene glycol) is used in leather processing as a moisturizing agent to soften and condition hides and skins during the tanning process, resulting in supple and flexible leather products.

MPG (Monopropylene glycol) is used as a diluent or solvent for intravenous medications and injectable drugs administered in healthcare settings, ensuring proper dissolution and delivery of pharmaceutical compounds.
MPG (Monopropylene glycol) is employed as a lubricant and coolant in medical devices such as catheters, endoscopes, and surgical instruments to reduce friction and heat generation during use, improving patient comfort and safety.
MPG (Monopropylene glycol) is included in cell culture media formulations as a cryoprotectant and osmotic stabilizer to maintain cell viability and integrity during freezing, thawing, and long-term storage in biomedical research laboratories.

MPG (Monopropylene glycol) is utilized across many different industries and some chemical manufacturers produce two grades of MPG to meet these varied needs.
The first grade is used in the food, cosmetics, and pharmaceutical industries.
MPG (Monopropylene glycol) is used as a solvent for food colourings and flavourings.

In the personal care industry it is used as a moisturiser in make-up, shampoo, bubble bath and baby wipes, to name but a few examples.
The pharmaceutical industry uses MPG (Monopropylene glycol) as a solvent in oral, injectable, and topical formulations.
The main application for industrial grade MPG (Monopropylene glycol) is as an antifreeze and aircraft wing and runway de-icer because the freezing point of MPG lowers upon mixing with water.

MPG (Monopropylene glycol) is also used in heat transfer liquids such as engine coolants.
MPG (Monopropylene glycol) can also be used as a chemical intermediate in the production of high performance unsaturated polyester resins used in paints and varnishes.
MPG (Monopropylene glycol) is also an excellent solvent that is utilised in printing inks and it is also used in the manufacture of detergents which are used in the petroleum, sugar-refining, and paper making industries.

MPG (Monopropylene glycol) is used as a humecant in food and cosmetics to maintain moisture levels in products.
These can include marshmallows, coconut flakes, shampoo and baby wipes along with many other products.
MPG (Monopropylene glycol) is used as an antifreeze for various reasons, including as an engine coolant additive, home water pipes and food processing systems.

Because MPG (Monopropylene glycol) is non toxic, it is safe to use in food applications where accidental ingestion may occur.
This gives MPG (Monopropylene glycol) a huge advantage over other antifreezes.
MPG (Monopropylene glycol) is used as a humectant in food products to help retain moisture and prevent them from drying out.

MPG (Monopropylene glycol) is commonly found in baked goods, confectionery, snacks, and processed foods.
MPG (Monopropylene glycol) serves as a solvent for flavors, colors, and food additives, aiding in their dispersion and incorporation into food products.
MPG (Monopropylene glycol) is added to powdered food products to prevent clumping and improve flowability.

MPG (Monopropylene glycol) is used as a solvent for active pharmaceutical ingredients (APIs) in oral and injectable medications, including syrups, elixirs, and liquid formulations.
MPG (Monopropylene glycol) serves as an excipient in pharmaceutical formulations to enhance drug solubility, stability, and bioavailability.
MPG (Monopropylene glycol) is a common ingredient in topical products such as creams, lotions, gels, and ointments, where it acts as a vehicle for delivering active ingredients to the skin.

MPG (Monopropylene glycol) helps maintain skin hydration by attracting and retaining moisture.
MPG (Monopropylene glycol) is used in moisturizers, creams, lotions, and facial cleansers.
MPG (Monopropylene glycol) serves as a solvent for fragrances, botanical extracts, and other cosmetic ingredients, ensuring their proper dispersion and stability.

MPG (Monopropylene glycol) is added to shampoos, conditioners, and hair styling products to improve texture, manageability, and moisture retention.
MPG (Monopropylene glycol) is a key component in automotive antifreeze formulations, where it helps prevent freezing and boiling of engine coolant, protecting the engine from temperature extremes.
MPG (Monopropylene glycol) is used as a hydraulic fluid in automotive power steering systems and brake fluids due to its low viscosity and excellent thermal stability.

MPG (Monopropylene glycol) is utilized in industrial processes as a humectant in textile manufacturing, paper production, and tobacco processing.
MPG (Monopropylene glycol) also serves as a solvent for resins, dyes, and specialty chemicals.
MPG (Monopropylene glycol) is used as a heat transfer fluid in industrial heating and cooling systems, as well as in refrigeration equipment, due to its low freezing point and high boiling point.

MPG (Monopropylene glycol) is employed in deicing solutions for aircraft, runways, roads, and sidewalks to melt ice and snow during winter weather conditions.
MPG (Monopropylene glycol) is also used as an antifreeze agent for water-based systems in cold climates.
In the tobacco industry, MPG (Monopropylene glycol) is added to tobacco products to maintain moisture content and improve flavor.

MPG (Monopropylene glycol) is used as a component in drilling fluids, as well as in gas dehydration and natural gas processing.
MPG (Monopropylene glycol) is used as a solvent and diluent in the formulation of printing inks for offset, flexographic, and gravure printing processes.

Toxicity evaluation:
MPG (Monopropylene glycol) has a low degree of toxicity in animals as well as humans, such that very high doses are needed to elicit effects in acute toxicity studies.
The toxic effects of propylene glycol appear to be similar in animals and in humans.
Central nervous system (CNS) depression, hematologic toxicity, hyperosmolarity, metabolic acidosis, cardiovascular effects, and renal toxicity encompass the main acute and subacute syndromes for MPG (Monopropylene glycol).

Most of the effects of MPG (Monopropylene glycol) can be ascribed to high concentrations of the parent molecule or to the accumulation of D,L-lactate in the blood.
Due to its alcohol moiety, MPG (Monopropylene glycol) at very high concentrations is the most likely reason for the CNS depression.
Also, because high concentrations of MPG (Monopropylene glycol) will increase the osmolarity of the blood, the hyperosmotic effects are likely due to the parent molecule.

The cardiovascular and renal effects may be a result of the hyperosmolarity in combination with the metabolic acidosis.
The acidosis itself results from the accumulation of lactate (both D- and L-forms), which has been well documented in both animals and humans.

Environmental Fate:
MPG (Monopropylene glycol) can be released into the environment via industrial releases or by disposal of consumer products.
MPG (Monopropylene glycol) is readily soluble in water and has a low sorption partition coefficient (KOC), so has the ability to move through soil and to leach into ground water.
Because of low vapor pressure (0.1 mmHg at 25°C) and high water solubility, there is minimal volatilization to the atmosphere from surface water releases as well as substantial removal of its vapors by wet deposition.

Its low octanol/water partition coefficient (KOW) indicates that bioconcentration and biomagnification should not happen.
MPG (Monopropylene glycol) is readily degraded in surface water and soil, by chemical oxidation and microbial digestion, with a short half-life (1–5 days) in aerobic or anaerobic conditions.

MPG (Monopropylene glycol) is also rapidly degraded in the atmosphere by photochemical oxidation, with a half-life about 1 day.
Although environmental releases can and do occur (airports must monitor storm water runoff of deicing solutions), human health effects are likely to be minor, at least in comparison to effects from potential exposures in clinical scenarios.

Safety Profile:
Slightly toxic by ingestion, skin contact, intraperitoneal, intravenous, subcutaneous, and intramuscular routes.
Human systemic effects by ingestion: general anesthesia, convulsions, changes in surface EEG.
Experimental teratogenic and reproductive effects.

An eye and human skin irritant.
Mutation data reported.
Combustible liquid when exposed to heat or flame; can react with oxidizing materials.

Explosive in the form of vapor when exposed to heat or flame.
May react with hydrofluoric acid + nitric acid + silver nitrate to form the explosive silver fulminate.

To fight fire, use alcohol foam.
When heated to decomposition it emits acrid smoke and irritating fumes.


MPP MELAMINE POLYPHOSPHATE FLAME RETARDANT

MPP melamine polyphosphate flame retardant (MPP) is a chemical compound primarily used as a flame retardant and smoke suppressant in various applications.
MPP melamine polyphosphate flame retardant is composed of repeating units of melamine and phosphoric acid, forming a polymeric structure.

CAS Number: 218768-84-4
EC Number: 244-575-5

MPP, Melapur 200, Melamine phosphate, Melaphos, Melapur MP, Melapur 110, Melamine acid phosphate, Melaminephosphoric acid, Melamine-pyrophosphoric acid, Melamid 25, Melamine orthophosphate, Melapur MP 200, Melaphos 201, Melapur MP-200, Melapur MP 100, Melaminophosphoric acid, Melaminepyrophosphoric acid, Melaminic acid phosphate, Melaminic acid phosphoric ester, Melapur 200F, Melapur MP100, Melapur 200F-40, Melapur 200-F 40, Melaminphosphorsäure, Melamin-pyrophosphorsäure, Melamin phosphorsäure, Melapur 100, Melapur 100F, Melapur MPF, Melamin phosphorsäureester, Melapur MP-100, Melapur MPF-40, Melapur MP 200F-40, Melapur MP 100F, Melaphos MP-100, Melapur MP 100 F, Melaminophosphorsäureester, Melamin-phosphorsäureester, Melapur MP 100-F, Melapur MP 100F-40, Melapur MP 100 F-40, Melapur MPF-20, Melaminphosphorsäureesterverbindung, Melamin-phosphorsäureesterverbindung, Melapur MPF-15, Melapur MP 100-F 40, Melapur 200F-20, Melapur MP 200-F20, Melapur MP 100 F-20, Melaphos 100F, Melaminphosphorsäureverbindung, Melamin-phosphorsäureverbindung, Melaminophosphorsäureverbindung, Melapur MPF-50, Melapur MPF-25, Melamin-phosphorsäureester



APPLICATIONS


MPP melamine polyphosphate flame retardant is commonly used as a flame retardant additive in the production of polymer-based materials.
MPP melamine polyphosphate flame retardant finds extensive application in the manufacturing of flame-retardant plastics, including polyethylene, polypropylene, and polyethylene terephthalate (PET).

MPP melamine polyphosphate flame retardant is utilized in the formulation of fire-resistant coatings and paints for architectural, industrial, and automotive applications.
MPP melamine polyphosphate flame retardant is incorporated into intumescent coatings, which swell and form a protective char layer when exposed to fire, providing passive fire protection.

MPP melamine polyphosphate flame retardant is employed in the production of flame-retardant textiles, such as curtains, upholstery fabrics, and protective clothing.
MPP melamine polyphosphate flame retardant is used in the manufacturing of flame-retardant foams for upholstered furniture, mattresses, and automotive seating.
MPP melamine polyphosphate flame retardant is added to thermosetting resins, such as epoxy and phenolic resins, to impart fire resistance to composite materials and laminates.

MPP melamine polyphosphate flame retardant is utilized in the production of flame-retardant adhesives and sealants for construction, electronics, and aerospace applications.
MPP melamine polyphosphate flame retardant is incorporated into electrical and electronic components to improve their fire safety performance and comply with industry standards.

MPP melamine polyphosphate flame retardant is used in the production of fire-resistant cable insulation and sheathing materials for applications requiring enhanced electrical safety.
MPP melamine polyphosphate flame retardant finds application in the formulation of fire-resistant coatings for wood, plywood, and engineered wood products.
MPP melamine polyphosphate flame retardant is added to paper and cardboard products to enhance their fire resistance and reduce the risk of fire propagation.

MPP melamine polyphosphate flame retardant is employed in the production of fire-resistant thermoplastic elastomers (TPEs) for automotive, wire and cable, and consumer goods applications.
MPP melamine polyphosphate flame retardant is utilized in the manufacturing of fire-resistant building materials, including insulation boards, roofing membranes, and wall panels.

MPP melamine polyphosphate flame retardant is added to polyurethane foams to improve their fire safety properties and meet regulatory requirements for construction materials.
MPP melamine polyphosphate flame retardant finds application in the production of fire-resistant gaskets, seals, and packing materials for industrial and automotive applications.

MPP melamine polyphosphate flame retardant is used in the formulation of fire-retardant coatings for steel and other structural materials to enhance their fire resistance.
MPP melamine polyphosphate flame retardant is added to polymer composites used in marine applications to reduce the flammability of boat components and structures.

MPP melamine polyphosphate flame retardant is employed in the production of fire-resistant paints and coatings for offshore platforms, oil refineries, and chemical processing plants.
MPP melamine polyphosphate flame retardant finds application in the production of fire-resistant molded products, such as electrical enclosures, junction boxes, and circuit breakers.
MPP melamine polyphosphate flame retardant is added to plastic films and packaging materials to improve their fire resistance and reduce the risk of fire spread.

MPP melamine polyphosphate flame retardant is utilized in the formulation of fire-resistant insulating materials for thermal and acoustic insulation in buildings and industrial equipment.
MPP melamine polyphosphate flame retardant finds application in the production of fire-resistant automotive components, such as dashboard panels, door trims, and engine covers.

MPP melamine polyphosphate flame retardant is added to rubber compounds used in conveyor belts, hoses, and automotive tires to enhance their fire resistance.
MPP melamine polyphosphate flame retardant is employed in the formulation of fire-resistant coatings for metal surfaces, such as steel beams, columns, and structural supports, to improve their fire safety performance.

MPP melamine polyphosphate flame retardant is incorporated into fireproof curtains and drapes used in commercial buildings and public spaces to prevent the spread of fire.
MPP melamine polyphosphate flame retardant is used in the production of fire-resistant filters for industrial processes where high temperatures or combustible materials are present.

MPP melamine polyphosphate flame retardant is added to firefighting foams and extinguishing agents to enhance their effectiveness in suppressing flames and smothering fires.
MPP melamine polyphosphate flame retardant finds application in the production of fire-resistant coatings for structural steel members in bridges, tunnels, and industrial facilities.

MPP melamine polyphosphate flame retardant is utilized in the formulation of fire-resistant adhesives and sealants for bonding materials in construction and manufacturing processes.
MPP melamine polyphosphate flame retardant is added to fireproof paints and varnishes used in marine applications to protect ship structures from fire hazards.
MPP melamine polyphosphate flame retardant is incorporated into fire blankets and wraps used to extinguish small fires and shield individuals from flames and heat.

MPP melamine polyphosphate flame retardant finds application in the production of fire-resistant wallpaper and wall coverings for residential and commercial interiors.
MPP melamine polyphosphate flame retardant is used in the manufacturing of fire-resistant building panels and cladding systems for facades and curtain walls.
MPP melamine polyphosphate flame retardant is added to fire-resistant lubricants and greases used in machinery and equipment operating in high-temperature environments.

MPP melamine polyphosphate flame retardant is employed in the production of fire-resistant coatings for steel storage tanks and pipelines in petrochemical and oil refining industries.
MPP melamine polyphosphate flame retardant is used in the formulation of fire-resistant mulches and landscaping materials to reduce the risk of wildfires in urban and wildland areas.
MPP melamine polyphosphate flame retardant finds application in the production of fire-resistant filters and barriers for HVAC systems and air filtration units.

MPP melamine polyphosphate flame retardant is added to fire-resistant paints and coatings used in aerospace applications to protect aircraft components from fire damage.
MPP melamine polyphosphate flame retardant is utilized in the manufacturing of fire-resistant electrical enclosures and cabinets for housing sensitive electronic equipment.
MPP melamine polyphosphate flame retardant is incorporated into fire-resistant mortars and grouts used in masonry construction to improve fire ratings and structural integrity.

MPP melamine polyphosphate flame retardant finds application in the production of fire-resistant window films and glazing systems for enhancing the fire safety of buildings.
MPP melamine polyphosphate flame retardant is used in the formulation of fire-resistant concrete and masonry blocks for constructing fire barriers and containment walls.
MPP melamine polyphosphate flame retardant is added to fire-resistant composites used in railway infrastructure to reduce the risk of train fires and improve passenger safety.

MPP melamine polyphosphate flame retardant is employed in the production of fire-resistant coatings for storage cabinets and containers used to store flammable chemicals and hazardous materials.
The compound finds application in the production of fire-resistant coatings for industrial chimneys and exhaust stacks to mitigate fire hazards.

MPP melamine polyphosphate flame retardant is added to fire-resistant fabrics and textiles used in military uniforms and protective gear for firefighters.
It is utilized in the formulation of fire-resistant coatings for concrete tunnels and underground structures to enhance fire safety in transportation systems.

MPP melamine polyphosphate flame retardant is used in the manufacturing of fire-resistant seals and gaskets for preventing the spread of flames and smoke in industrial equipment.
MPP melamine polyphosphate flame retardant finds application in the production of fire-resistant insulation materials for insulating pipes, ducts, and mechanical systems in buildings and facilities.

MPP melamine polyphosphate flame retardant is added to fire-resistant paints and coatings used in historical buildings and heritage structures to preserve architectural integrity.
It finds application in the production of fire-resistant barriers and curtains for stage performances and theatrical productions.

MPP melamine polyphosphate flame retardant is utilized in the formulation of fire-resistant materials for the construction of high-rise buildings and skyscrapers.
MPP melamine polyphosphate flame retardant is incorporated into fire-resistant door cores and frames for residential and commercial buildings to improve fire safety.

MPP melamine polyphosphate flame retardant is used in the manufacturing of fire-resistant barriers and screens for industrial processes involving combustible materials.
MPP melamine polyphosphate flame retardant finds application in the production of fire-resistant furniture components, such as chair frames and table legs, for public spaces.
MPP melamine polyphosphate flame retardant is added to fire-resistant coatings for storage racks and shelves in warehouses and distribution centers.

MPP melamine polyphosphate flame retardant is utilized in the formulation of fire-resistant ceiling tiles and panels for suspended ceiling systems in commercial and institutional buildings.
MPP melamine polyphosphate flame retardant is employed in the production of fire-resistant wallboard and gypsum panels for interior partitions and wall assemblies.
MPP melamine polyphosphate flame retardant is added to fire-resistant composites used in the construction of railway platforms and station facilities.

MPP melamine polyphosphate flame retardant finds application in the production of fire-resistant signage and wayfinding systems for guiding occupants during emergencies.
MPP melamine polyphosphate flame retardant is used in the manufacturing of fire-resistant barriers and enclosures for electrical substations and power distribution facilities.
MPP melamine polyphosphate flame retardant is incorporated into fire-resistant insulation materials for insulating HVAC ductwork and ventilation systems.

MPP melamine polyphosphate flame retardant is added to fire-resistant paints and coatings used in industrial facilities to protect equipment and machinery from fire damage.
MPP melamine polyphosphate flame retardant finds application in the production of fire-resistant wall coverings and decorative finishes for commercial interiors.
MPP melamine polyphosphate flame retardant is utilized in the formulation of fire-resistant coatings for structural steel beams and columns in building construction.

MPP melamine polyphosphate flame retardant is employed in the manufacturing of fire-resistant flooring materials for hospitals, schools, and other high-traffic areas.
MPP melamine polyphosphate flame retardant finds application in the production of fire-resistant roofing membranes and shingles for residential and commercial buildings.
MPP melamine polyphosphate flame retardant is added to fire-resistant insulation boards and panels for thermal insulation in building envelopes.

MPP melamine polyphosphate flame retardant is used in the formulation of fire-resistant coatings for offshore drilling platforms and oil rig structures.
MPP melamine polyphosphate flame retardant finds application in the production of fire-resistant conveyor belts and materials handling equipment for industrial facilities.
MPP melamine polyphosphate flame retardant is incorporated into fire-resistant coatings for structural timber and wood products in construction.

MPP melamine polyphosphate flame retardant is utilized in the formulation of fire-resistant coatings for underground tunnels and transportation infrastructure.
MPP melamine polyphosphate flame retardant is employed in the manufacturing of fire-resistant coatings for storage tanks and containment vessels in chemical plants.
MPP melamine polyphosphate flame retardant finds application in the production of fire-resistant coatings for marine vessels and offshore structures.



DESCRIPTION


MPP melamine polyphosphate flame retardant (MPP) is a chemical compound primarily used as a flame retardant and smoke suppressant in various applications.
MPP melamine polyphosphate flame retardant is composed of repeating units of melamine and phosphoric acid, forming a polymeric structure.

MPP melamine polyphosphate flame retardant is valued for its ability to inhibit the spread of fire by forming a protective char layer when exposed to heat or flames.
This char layer acts as a barrier, insulating the underlying material and reducing the release of flammable gases.

MPP is commonly used in plastics, coatings, textiles, and construction materials to enhance fire safety properties.
MPP melamine polyphosphate flame retardant is known for its thermal stability, low toxicity, and compatibility with a wide range of polymers, making it a versatile flame retardant additive.


MPP melamine polyphosphate flame retardant is a white, crystalline powder with a fine texture.
It possesses excellent flame-retardant properties, making it highly effective in reducing the spread of fire.

MPP melamine polyphosphate flame retardant forms a protective char layer when exposed to heat or flames, acting as a barrier against further combustion.
MPP melamine polyphosphate flame retardant is odorless and non-toxic, ensuring safety in various applications.

MPP melamine polyphosphate flame retardant is soluble in water and compatible with a wide range of polymers, including plastics, resins, and rubbers.
MPP melamine polyphosphate flame retardant exhibits remarkable thermal stability, retaining its effectiveness even at elevated temperatures.
MPP melamine polyphosphate flame retardant is often used in combination with other flame retardants to achieve synergistic effects and enhance overall fire resistance.

MPP melamine polyphosphate flame retardant finds widespread application in the manufacturing of fire-resistant coatings, paints, and sealants for building materials.
MPP melamine polyphosphate flame retardant is also utilized in the production of flame-retardant textiles, carpets, and upholstery fabrics.
MPP melamine polyphosphate flame retardant can be incorporated into polymer matrices through various processing methods, ensuring versatility in application.

MPP melamine polyphosphate flame retardant imparts minimal changes to the physical properties of materials, maintaining mechanical strength and flexibility.
MPP melamine polyphosphate flame retardant's low toxicity profile and environmental compatibility make it a preferred choice for flame retardant formulations.

MPP melamine polyphosphate flame retardant exhibits excellent compatibility with halogen-containing flame retardants, further enhancing fire resistance.
MPP melamine polyphosphate flame retardant is known for its ability to suppress smoke and toxic gas emissions during combustion, contributing to improved fire safety.

MPP melamine polyphosphate flame retardant is resistant to leaching and migration, ensuring long-lasting fire protection in treated materials.
MPP melamine polyphosphate flame retardant demonstrates good dispersibility in polymer matrices, facilitating uniform distribution and effective flame retardant action.

MPP melamine polyphosphate flame retardant remains stable under a wide range of processing conditions, including high temperatures and shear rates.
MPP melamine polyphosphate flame retardant offers cost-effective fire protection solutions compared to some alternative flame retardants.
Its versatility and compatibility with various substrates make it suitable for use in diverse industries, including construction, automotive, and electronics.

MPP melamine polyphosphate flame retardant undergoes controlled decomposition when exposed to fire, releasing inert gases that inhibit combustion.
MPP melamine polyphosphate flame retardant is characterized by its high purity and consistency, ensuring reliable performance in flame retardant applications.

MPP melamine polyphosphate flame retardant is resistant to hydrolysis and degradation, maintaining its fire-retardant properties over extended periods.
MPP melamine polyphosphate flame retardant's low dusting properties minimize handling hazards and reduce the risk of airborne contamination during processing.

MPP melamine polyphosphate flame retardant complies with stringent regulatory requirements and industry standards for fire safety and environmental protection.
Its effectiveness, versatility, and safety profile make MPP melamine polyphosphate flame retardant a valuable additive in materials requiring enhanced flame resistance.



PROPERTIES


Appearance: White powder
Chemical Formula: HO(C3H7N6PO3)nH
N content (%): 42 to 44
P content (%): 12 to 14
pH value (10g/L): 4 to 6
Particle size µm MPP-A: D50 ≤ 2.5, D98 ≤ 30
Particle size µm MPP-B: D50 ≤ 1.7, D98 ≤ 18
Bulk density kg/m³: 300 to 500
Solubility (20°C) g/L: ≤ 0.05
Decomposition temperature MPP-A: ≥ 375°C
Decomposition temperature MPP-B: ≥ 360°C



FIRST AID


Inhalation:

Move to Fresh Air:
If MPP melamine polyphosphate flame retardant dust or fumes are inhaled, immediately move the affected person to an area with fresh air.

Ensure Breathing:
Check the person's airway, breathing, and circulation.
If breathing is difficult, ensure an open airway and provide rescue breathing if necessary.

Seek Medical Attention:
If symptoms such as difficulty breathing, coughing, or respiratory distress persist, seek medical attention promptly.

Provide Oxygen:
If available and trained to do so, administer oxygen to the affected person while awaiting medical assistance.

Keep Calm and Reassure:
Keep the affected person calm and reassure them while waiting for medical help.


Skin Contact:

Remove Contaminated Clothing:
If MPP melamine polyphosphate flame retardant comes into contact with the skin, promptly remove any contaminated clothing.

Wash Skin Thoroughly:
Wash the affected area with soap and water for at least 15 minutes, ensuring thorough rinsing to remove any traces of MPP melamine polyphosphate flame retardant.

Use Mild Soap:
Use a mild soap or detergent to gently cleanse the skin, avoiding harsh chemicals that may exacerbate irritation.

Apply Moisturizer:
After washing, apply a soothing moisturizer or emollient to the affected area to help soothe and hydrate the skin.

Seek Medical Advice:
If skin irritation persists or worsens, seek medical advice or consult a healthcare professional for further evaluation and treatment.


Eye Contact:

Flush with Water:
Immediately flush the eyes with lukewarm water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.

Remove Contact Lenses:
If wearing contact lenses, remove them as soon as possible to facilitate irrigation of the eyes.

Seek Medical Attention:
Seek immediate medical attention or contact an eye specialist if irritation, pain, or redness persists after flushing.


Ingestion:

Do Not Induce Vomiting:
Do not induce vomiting if MPP melamine polyphosphate flame retardant has been ingested, as it may lead to further complications.

Do Not Drink Water:
Refrain from giving anything by mouth to the affected person unless instructed by medical personnel.

Seek Medical Assistance:
Immediately contact a poison control center or seek medical assistance for further guidance and treatment.

Provide Information:
Provide medical personnel with details regarding the amount ingested, the time of ingestion, and any symptoms experienced by the affected person.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including chemical-resistant gloves, safety glasses or goggles, and protective clothing (such as long sleeves and pants), when handling MPP melamine polyphosphate flame retardant to minimize skin and eye contact.

Avoid Inhalation:
Avoid breathing in dust or fumes generated during handling.
Use local exhaust ventilation or wear a respiratory protective device if necessary.

Prevent Skin Contact:
Prevent skin contact by wearing gloves and long-sleeved clothing.
In case of skin contact, wash affected areas thoroughly with soap and water.

Prevent Eye Contact:
Wear safety glasses or goggles to protect eyes from potential splashes.
In case of eye contact, flush eyes with water immediately and seek medical attention if irritation persists.

Minimize Dust Generation:
Handle MPP melamine polyphosphate flame retardant in a manner that minimizes dust generation.
Use appropriate handling and transfer equipment to reduce the risk of airborne exposure.

Avoid Contamination:
Prevent contamination of food, beverages, and tobacco products with MPP melamine polyphosphate flame retardant.
Wash hands thoroughly after handling and before eating, drinking, or smoking.

Dispose of Waste Properly:
Dispose of waste materials, such as empty containers or spilled product, in accordance with local regulations and guidelines for hazardous waste disposal.


Storage:

Container Selection:
Store MPP melamine polyphosphate flame retardant in tightly sealed containers made of compatible materials, such as polyethylene or stainless steel, to prevent moisture ingress and contamination.

Labeling:
Clearly label containers with the product name, hazard symbols, handling instructions, and storage conditions to ensure proper identification and safe handling.

Temperature Control:
Store MPP melamine polyphosphate flame retardant in a cool, dry place away from direct sunlight and heat sources.
Avoid exposure to extreme temperatures, which may affect product stability.

Ventilation:
Ensure adequate ventilation in storage areas to prevent the buildup of dust or vapors.
Use mechanical ventilation or natural ventilation as appropriate.

Separation:
Store MPP melamine polyphosphate flame retardant away from incompatible materials, including acids, bases, oxidizing agents, and strong reducing agents, to prevent chemical reactions or hazards.

Avoid Stacking:
Avoid stacking containers of MPP melamine polyphosphate flame retardant to prevent damage or collapse.
Store containers on shelves or racks with adequate support and spacing.

Handling Precautions:
Handle containers with care to prevent spills or leaks.
Use appropriate lifting equipment and techniques when moving or transporting heavy containers.

Security Measures:
Implement security measures, such as locked storage areas or restricted access, to prevent unauthorized handling or tampering with MPP melamine polyphosphate flame retardant.

Emergency Response:
Have appropriate spill containment and cleanup materials readily available in case of spills or leaks.
Train personnel on proper spill response procedures and emergency protocols.
MSP (MONO SODIUM PHOSPHATE)
3-Methylbenzoic acid; M-Toluylic acid; m-methylbenzoic acid; m-toluylic acid; m-Methylbenzoate; beta-methylbenzoic acid CAS NO:99-04-7
MULTISOL C10 ACID
Multisol C10 Acid Multisol C10 acid, also known as decanoic acid or decylic acid, is a saturated fatty acid. Its formula is CH3(CH2)8COOH. Salts and esters of decanoic acid are called caprates or decanoates. The term Multisol C10 acid is derived from the Latin "caper / capra" (goat) because the sweaty, unpleasant smell of the compound is reminiscent of goats. Occurrence Multisol C10 acid occurs naturally in coconut oil (about 10%) and palm kernel oil (about 4%), otherwise it is uncommon in typical seed oils.[10] It is found in the milk of various mammals and to a lesser extent in other animal fats.[6] It also comprises 1.62% of the fats from the fruit of the durian species Durio graveolens. Two other acids are named after goats: caproic acid (a C6:0 fatty acid) and caprylic acid (a C10:0 fatty acid). Along with Multisol C10 acid, these total 15% in goat milk fat. Production of Multisol C10 acid Multisol C10 acid can be prepared from oxidation of the primary alcohol decanol by using chromium trioxide (CrO3) oxidant under acidic conditions. Neutralization of Multisol C10 acid or saponification of its triglyceride esters with sodium hydroxide yields sodium caprate, CH3(CH2)8CO2−Na+. This salt is a component of some types of soap. Uses of Multisol C10 acid Multisol C10 acid is used in the manufacture of esters for artificial fruit flavors and perfumes. It is also used as an intermediate in chemical syntheses. It is used in organic synthesis and industrially in the manufacture of perfumes, lubricants, greases, rubber, dyes, plastics, food additives and pharmaceuticals. Pharmaceuticals Caprate ester prodrugs of various pharmaceuticals are available. Since Multisol C10 acid is a fatty acid, forming a salt or ester with a drug will increase its lipophilicity and its affinity for adipose tissue. Since distribution of a drug from fatty tissue is usually slow, one may develop a long-acting injectable form of a drug (called a depot injection) by using its caprate form. Some examples of drugs available as a caprate ester include nandrolone, fluphenazine, bromperidol, and haloperidol. Effects of Multisol C10 acid Multisol C10 acid acts as a non-competitive AMPA receptor antagonist at therapeutically relevant concentrations, in a voltage- and subunit-dependent manner, and this is sufficient to explain its antiseizure effects.[14] This direct inhibition of excitatory neurotransmission by Multisol C10 acid in the brain contributes to the anticonvulsant effect of the MCT ketogenic diet.[14] Decanoic acid and the AMPA receptor antagonist drug perampanel act at separate sites on the AMPA receptor, and so it is possible that they have a cooperative effect at the AMPA receptor, suggesting that perampanel and the ketogenic diet could be synergistic. Multisol C10 acid may be responsible for the mitochondrial proliferation associated with the ketogenic diet, and that this may occur via PPARγ receptor agonism and its target genes involved in mitochondrial biogenesis. Complex I activity of the electron transport chain is substantially elevated by decanoic acid treatment. It should however be noted that orally ingested medium chain fatty acids would be very rapidly degraded by first-pass metabolism by being taken up in the liver via the portal vein, and are quickly metabolized via coenzyme A intermediates through β-oxidation and the citric acid cycle to produce carbon dioxide, acetate and ketone bodies.[17] Whether the ketones β-hydroxybutryate and acetone have direct antiseizure activity is unclear. Multisol C10 acid is a white crystalline solid with a rancid odor. Melting point 31.5°C. Soluble in most organic solvents and in dilute nitric acid; non-toxic. Used to make esters for perfumes and fruit flavors and as an intermediate for food-grade additives. The most common source of Salmonella infections in humans is food of poultry origin. Salmonella enterica serovar Enteritidis has a particular affinity for the contamination of the egg supply. In this study, the medium-chain fatty acids (MCFA), caproic, caprylic, and Multisol C10 acid, were evaluated for the control of Salmonella serovar Enteritidis in chickens. All MCFA were growth inhibiting at low concentrations in vitro, with Multisol C10 acid being the most potent. Contact of Salmonella serovar Enteritidis with low concentrations of MCFA decreased invasion in the intestinal epithelial cell line T84. By using transcriptional fusions between the promoter of the regulatory gene of the Salmonella pathogenicity island I, hilA, and luxCDABE genes, it was shown that all MCFA decreased the expression of hilA, a key regulator related to the invasive capacity of Salmonella. The addition of Multisol C10 acid (3 g/kg of feed) to the feed of chicks led to a significant decrease in the level of colonization of ceca and internal organs by Salmonella serovar Enteritidis at 3 days after infection of 5-day-old chicks. These results suggest that MCFA have a synergistic ability to suppress the expression of the genes required for invasion and to reduce the numbers of bacteria in vivo. Thus, MCFA are potentially useful products for reducing the level of colonization of chicks and could ultimately aid in the reduction of the number of contaminated eggs in the food supply. The rate of intestinal absorption and hepatic uptake of medium chain fatty acids (MCFA) was investigated in 6 pigs. The pigs were fitted with a permanent fistula in the duodenum, and catheters in the portal vein, carotid artery and hepatic vein. Multisol C10 acid (esterified with octanoic acid) was infused into the duodenum for 1 hr. Regular blood samples were taken over 12 hr and analysed for non-esterified Multisol C10 acid content. Multisol C10 acid levels in portal vein blood rose sharply after the beginning of the infusion (confirming data previously reported for dogs and rats), and showed a bi-phasic time course with 2 maximum values (at 15 min and 75 to 90 min). 54% of the Multisol C10 acid was recovered in portal blood samples. The amt of non-esterified MCFA taken up per hr by the liver were close to those absorbed from the gut via the portal vein, showing that the liver is the main site of MCFA metabolism in pigs. Distillation Range (°C) Boiling Point 270 Flash Point (°C) 150 Purity (%m/m) C10 @ Min 98 Density (@ 20°C)(*@15°C) 0.850 An exemption from the requirement of a tolerance is established for residues of Multisol C10 acid in or on all raw agricultural commodities and in processed commodities, when such residues result from the use of Multisol C10 acid as an antimicrobial treatment in solutions containing a diluted end-use concentration of Multisol C10 acid (up to 170 ppm per application) on food contact surfaces such as equipment, pipelines, tanks, vats, fillers, evaporators, pasteurizers and aseptic equipment in restaurants, food service operations, dairies, breweries, wineries, beverage and food processing plants The enhancing action of Multisol C10 acid on the intestinal absorption of phenosulfonphthalein (PSP) was studied in rats. Multisol C10 acid and 2 hydroxy derivatives enhanced PSP absorption to varying degrees; PSP was no longer absorbed once the enhancer had been completely absorbed. Absorption enhancement correlated with the ability to sequester calcium ions. Multisol C10 acid's production and use in esters for perfumes and fruit flavor, base for wetting agents, intermediates, plasticizer, resins, and as an intermediate for food-grade additives may result in its release to the environment through various waste streams. Multisol C10 acid has been found in the seeds of American elm (Ulmus americana) and Garcinia mangostana, oil of lime and lemon, and occurs as a glyceride in natural oils. Multisol C10 acid is a fatty acid and occurs naturally in many essential oils. Fatty acids are widely distributed in nature as components of animal and vegetable fats and are an important part of the normal daily diet of mammals, birds and invertebrates. If released to air, a vapor pressure of 3.66X10-4 mm Hg at 25 °C indicates Multisol C10 acid will exist solely as a vapor in the atmosphere. Vapor-phase Multisol C10 acid will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 1.4 days. If released to soil, undissociated Multisol C10 acid is expected to have slight mobility based upon an estimated Koc of 4,000 for the free acid. The pKa of Multisol C10 acid is 4.90, indicating that this compound will exist almost entirely in anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts. Volatilization from moist soil surfaces is not expected to be an important fate process based upon the pKa. A 46% of theoretical BOD after 20 days using a sewage inoculum and 42% of theoretical BOD in 1 day using an activated sludge inoculum suggest that biodegradation may be important environmental fate process in soil. If released into water, undissociated Multisol C10 acid is expected to adsorb to suspended solids and sediment based upon the estimated Koc for the free acid. Biodegradation of 100 ppm Multisol C10 acid using a Japanese cultivation method was 100% in river water and 100% in sea water after 3 days, suggesting that biodegradtion may be an important environmental fate process in water. Volatilization from water surfaces is not expected to be an important fate process based upon the pKa. An estimated BCF of 3 suggests the potential for bioconcentration in aquatic organisms is low. Hydrolysis is not expected to be an important environmental fate process since this compound lacks functional groups that hydrolyze under environmental conditions. Occupational exposure to Multisol C10 acid may occur through inhalation and dermal contact with this compound at workplaces where Multisol C10 acid is produced or used. Monitoring data indicate that the general population may be exposed to Multisol C10 acid via inhalation of ambient air, ingestion of food and drinking water, and dermal contact with this compound and other containing Multisol C10 acid. Multisol C10 acid was found in fine particulate abrasion products from green leaves at a concn of 183.3 ug/g and from dead leaves at a concn of 133.0 ug/g; samples collected were from trees characteristic of the Los Angeles, CA area(1). Multisol C10 acid was found as a volatile component of raw earth-almond (Cyperus esculentus L.)(2). The compound is a carboxylic acid that is also known as a fatty acid because fatty acids were first isolated by the hydrolysis of naturally occurring fats(3). Fatty acids are widely distributed in nature as components of animal and vegetable fats(4) including lipids such as oils and fats, waxes, sterol esters and other minor compounds(3). Multisol C10 acid's production and use in esters for perfumes and fruit flavor, base for wetting agents, intermediates, plasticizer, resins and as an intermediate for food-grade additives(1) may result in its release to the environment through various waste streams(SRC). AEROBIC: The 5 day BOD of Multisol C10 acid, concn 100 ppm, was determined to be 8.52 mmol/mmol Multisol C10 acid using acclimated mixed microbial cultures in a mineral salt medium(1). Multisol C10 acid, present at 10,000 ppm, reached 45 to 53% and 46 to 54% of its theoretical BOD in 5 and 20 days, respectively, using a sewage inoculum(2). Multisol C10 acid, present at 10,000 ppm, reached 13, 45, and 46% of its theoretical BOD in 5, 10, and 20 days, respectively, using a sewage inoculum(3). In a similar study, Multisol C10 acid, present at 10,000 ppm, reached 49, 53, and 54% of its theoretical BOD in 5, 10, and 20 days, respectively, using an acclimated sewage inoculum(3). Multisol C10 acid, present at unknown concn, reached 9% of its theoretical BOD in 5 days using a sewage inoculum(4). Using the Warburg test method, Multisol C10 acid, present at 500 ppm, reached 29 to 42% of its theoretical BOD in 1 day, using an activated sludge inoculum with a microbial population of 2,500 mg/L corrected for endogenous respiration(5). Biodegradation of 100 ppm Multisol C10 acid using the cultivation method was 100% in river water and 100% in sea water after 3 days(6). The theoretical oxygen demand for 500 mg/L Multisol C10 acid was determined to be 10.9%, 18.9%, and 23.4% after 6, 12, and 24 hours of exposure to activated sludge solids at 2,500 mg/L in the Warburg respirometer(7). An aerobic biodegradation screening study of Multisol C10 acid, based on BOD measurements, using a sewage inoculum and an unknown Multisol C10 acid concn, indicated 23% of its theoretical BOD over a period of 20 days(8). The biodegradation of 100 mg/L Multisol C10 acid by non-acclimated activated sludge over an unspecified time period was determined to have 100% total organic carbon removal(9). The rate constant for the vapor-phase reaction of Multisol C10 acid with photochemically-produced hydroxyl radicals has been estimated as 1.1X10-11 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 1.4 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). Multisol C10 acid is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(2). Multisol C10 acid was present at 1.5 mg/L in the influent to a continuous retort water treatment cell; after 1, 3 and 5 weeks Multisol C10 acid was not detected, and after 7 weeks Multisol C10 acid was found at 108.6 mg/L, indicating adsorption followed by desorption(3). To assess the disposition kinetics of selected structural analogs of valproic acid, the pharmacokinetics of valproic acid and 3 structural analogs, cyclohexanecarboxylic acid, l-methyl-l-cyclohexanecarboxylic acid (1-methylcyclohexanecarboxylic acid; and Multisol C10 acid were examined in female rats. All 4 carboxylic acids evidenced dose-dependent disposition. A dose-related decrease in total body clearance was observed for each compound, suggesting saturable eiminination processes. The apparent volume of distribution for these compounds was, with the exception of cyclohexanecarboxylic acid, dose-dependent, indicating that binding to proteins in serum and/or tissues may be saturable. Both valproic acid and 1-methylcyclohexanecarboxylic acid exhibited enterohepatic recirculation, which appeared to be dose- and compound-dependent. Significant quantities of both valproic acid and 1-methylcyclohexanecarboxylic acid were excreted in the urine as conjugates. Multisol C10 acid and cyclohexanecarboxylic acid were not excreted in the urine and did not evidence enterohepatic recirculation. It was concluded that minor changes in chemical structure of low molecular weight carboxylic acids have an influence on their metabolism and disposition. For Multisol C10 acid (USEPA/OPP Pesticide Code:128919) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses. Multisol C10 acid is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and/or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B; 51FR21438). Daily application of 7.2% Multisol C10 acid in propanol under cover to the skin of 10 volunteers caused redness in 4 subjects after 2 days and in 8 after 6 days. Multisol C10 acid and its sodium and potassium salts caused skin irritation in man and the acid was an eye irritant in rabbits. Cytochrome oxidase activity was investigated histochemically in the choroid plexus epithelium. Intense staining for the enzyme was exclusively limited to the mitochondria. Rats treated with Multisol C10 acid displayed extensive ultrastructural disruptions in the epithelial cells of the choroid plexus. Mitochondria were fewer in number and more disrupted compared to the control. The enzyme activity was greatly reduced. However, pretreatment with an equimolar dose of L-carnitine followed by Multisol C10 acid injection produced little alteration of either ultrastructure or enzyme staining. This study suggests that L-carnitine supplementation may restore mitochondrial function of the choroid plexus subjected to toxic organic anions in metabolic disorders, and may be useful in the prevention of metabolic encephalopathy. HUMAN EXPOSURE STUDIES/ In 25 subjects, covered contact with 1% Multisol C10 acid in petrolatum for 48 hr was not irritating. The medium chain fatty acid Multisol C10 acid was injected i.p. into 20-22 g Swiss-Albino mice at a dose of 15 umol/g. This dose produced a reproducible response consisting of a 3-4 min period of drowsiness, followed by coma. These mice as well as suitable controls were sacrificed by rapid submersion in liquid N2, or by microwave irradiation in a 7.3 kW microwave oven. Tissue from the reticular formation and the inferior colliculus was prepared for microanalysis of the energy metabolites glucose, glycogen, ATP and phosphocreatine. Results from this study showed a selective effect on energy metabolism in cells of the reticular formation. Both glucose and glycogen were elevated in the coma and precoma state. In addition, ATP and phosphocreatine were decreased in the reticular formation during coma. These results show a selective effect of Multisol C10 acid on energy metabolism in the reticular formation both in the precoma stage, and during overt coma. Multisol C10 acid's production and use in the synthesis of various dyes, drugs, perfumes, antiseptics and fungicides, in ore separations, synthetic flavors, hydraulic fluids, machining oils, flotation agents, and as a wood preservative may result in its release to the environment through various waste streams. Multisol C10 acid is a fatty acid and is widely distributed in nature as a component of animal and vegetable fats. Fatty acids are an important part of the normal daily diet of mammals, birds and invertebrates. Multisol C10 acid can occur naturally in essential oils and in cow milk fat. If released to air, a vapor pressure of 3.71X10-3 mm Hg at 25 °C indicates Multisol C10 acid will exist solely as a vapor in the atmosphere. Vapor-phase Multisol C10 acid will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 1.9 days. If released to soil, undissociated Multisol C10 acid is expected to have low mobility based upon an estimated Koc of 1,100 for the free acid. The pKa of Multisol C10 acid is 4.89, indicating that this compound will exist almost entirely in anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts. Volatilization from moist soil surfaces is not expected to be an important fate process based upon the pKa. Biodegradation of Multisol C10 acid in soil and water is expected to be an important fate process; Multisol C10 acid reached 32.8% of its theoretical oxygen demand after 24 hours using an activated sludge inoculum. If released into water, undissociated Multisol C10 acid is expected to adsorb to suspended solids and sediment based upon the estimated Koc for the free acid. Volatilization from water surfaces is not expected to be an important fate process based on the pKa. An estimated BCF of 3 suggests the potential for bioconcentration in aquatic organisms is low. Hydrolysis is not expected to be an important environmental fate process since this compound lacks functional groups that hydrolyze under environmental conditions. Occupational exposure to Multisol C10 acid may occur through inhalation and dermal contact with this compound at workplaces where Multisol C10 acid is produced or used. Monitoring data indicate that the general population may be exposed to Multisol C10 acid via inhalation of ambient air, ingestion of food and drinking water, and dermal contact with this compound and other products containing Multisol C10 acid. The Multisol C10 acid content in milk fat of cows ranges from 0.53 to 1.04% of total fatty acids, with an average Multisol C10 acid content of 0.79% of total fatty acids(1). The compound is a carboxylic acid that is also known as a fatty acid because fatty acids were first isolated by the hydrolysis of naturally occurring fats(2). Fatty acids are widely distributed in nature as components of animal and vegetable fats(3) including lipids such as oils and fats, waxes, sterol esters and other minor compounds(2). Multisol C10 acid's production and use in the synthesis of various dyes, drugs, perfumes, antiseptics and fungicides, in ore separations, synthetic flavors(1), hydraulic fluids, machining oils, flotation agents, and as a wood preservative(2) may result in its release to the environment through various waste streams(SRC). TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 1,100 for the free acid(SRC), determined from a log Kow of 3.05(2) and a regression-derived equation(3), indicates that undissociated Multisol C10 acid is expected to have low mobility in soil(SRC). The pKa of Multisol C10 acid is 4.89(4), indicating that this compound will exist almost entirely in anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5). Volatilization of Multisol C10 acid from moist soil is not expected to be an important fate process because the acid is in the anion form and anions do not volatilize(SRC). Multisol C10 acid is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 3.71X10-3 mm Hg(6). In Warburg respirometer tests using an activated sludge seed, Multisol C10 acid reached 9.8, 20.4, and 32.8% of its theoretical oxygen demand after 6, 12, and 24 hours incubation, respectively(7), suggesting that biodegradation may be an important environmental fate process in soil(SRC). AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 1,100 for the free acid(SRC), determined from a log Kow of 3.05(2) and a regression-derived equation(3), indicates that undissociated Multisol C10 acid is expected to adsorb to suspended solids and sediment(SRC). A pKa of 4.89(4) indicates Multisol C10 acid will exist almost entirely in the anion form at pH values of 5 to 9 and therefore volatilization from water surfaces is not expected to be an important fate process(5). According to a classification scheme(6), an estimated BCF of 3(SRC), from its log Kow(2) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). In Warburg respirometer tests using an activated sludge seed, Multisol C10 acid reached 9.8, 20.4, and 32.8% of its theoretical oxygen demand after 6, 12, and 24 hours incubation, respectively(8), suggesting that biodegradation may be an important environmental fate process in water(SRC). ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), Multisol C10 acid, which has a vapor pressure of 3.71X10-3 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase Multisol C10 acid is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 1.9 days(SRC), calculated from its rate constant of 8.3X10-12 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Multisol C10 acid does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(4). AEROBIC: Multisol C10 acid reached 43, 53, 64 and 63% of its theoretical BOD after 2, 5, 10, and 30 days, respectively using a domestic sewage inoculum and an Multisol C10 acid concn of 3.0 ppm(1). 100% decreases in initial Multisol C10 acid concns of 0.5 mg/L and 4.3 mg/L were observed after 21 days incubation in aerobic mixed bacterial cultures obtained from trench leachate at low-level radioactive waste disposal sites in Maxey Flats, KY and West Valley, NY, respectively(2). Multisol C10 acid reached 60% of its theoretical oxygen demand after 5 days using a sewage seed(3). After a lag period of 2.2 days, Multisol C10 acid present at a concn of 10,000 ppm, reached 60, 66, and 68% of its theoretical BOD after 5, 10, and 20 days, respectively using a sewage seed(4). Use of an adapted sewage seed reduced the lag period to 1.6 days, after which Multisol C10 acid reached 60, 69, and 70% of its theoretical BOD after 5, 10, and 20 days, respectively(4). In Warburg respirometer tests using an activated sludge seed, Multisol C10 acid, present at a concn of 500 ppm, reached 9.8, 20.4, and 32.8% of its theoretical oxygen demand after 6, 12, and 24 hours incubation, respectively(5). After 24 hours incubation, Multisol C10 acid, present at a concn of 500 ppm, reached 5 and 59% of its theoretical oxygen demand using activated sludge inoculum from two different municipal sources(5). In a Warburg test using an activated sludge inoculum acclimated to phenol, Multisol C10 acid, present at a concn of 500 ppm, reached 20% of its theoretical BOD after 12 hours(6). Two bacterial soil isolants were able to utilize octanoate as a growth substrate(7). A total organic carbon removal ratio of 97% was observed for Multisol C10 acid using a non-acclimated activated sludge and an initial Multisol C10 acid concn of 100 mg total organic carbon/L(8). The rate constant for the vapor-phase reaction of Multisol C10 acid with photochemically-produced hydroxyl radicals has been estimated as 8.3X10-12 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 1.9 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). Multisol C10 acid is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(2). Multisol C10 acid does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(3). The Koc of undissociated Multisol C10 acid is estimated as 1,100 for the free acid(SRC), using a log Kow of 3.05(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that undissociated Multisol C10 acid is expected to have low mobility in soil. The pKa of Multisol C10 acid is 4.89(4), indicating that this compound will exist almost entirely in the anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5). Multisol C10 acid was detected in aqueous industrial effluent extracts collected between Nov 1979-81 in the following industrial categories (concentration in one effluent extract): paint and ink (119 ng/uL); printing and publishing (279 ng/uL); ore mining (43 ng/uL); organics and plastics (266 ng/uL); pulp and paper (399 ng/uL); rubber processing (1511 ng/uL); auto and other laundries (139 ng/uL); electronics (114 ng/uL); mechanical products (4976 ng/uL); and publicly owned treatment works at an unknown concn(1). Multisol C10 acid was detected in the leachate of a sanitary landfill located in Barcelona, Spain at an unreported concn(2). Oil shale retort water from the Kerosene Creek seam of the Rundle deposit, Queensland, Australia, was found to contain Multisol C10 acid at a concn of 270 mg/L(3). Multisol C10 acid was detected in groundwater from a landfill well near Norman, OK at an estimated concn of 0.6 ug/L(4). A grab sample, obtained in April 1980, of the final effluent from the Addison, IL Publicly Owned Treatment Works was found to contain Multisol C10 acid at an unreported concn(5). Multisol C10 acid was detected in Los Angeles County wastewater treatment plant effluent, collected between Nov 1980 and Aug 1981, at a concn of 400 ug/L(6). Multisol C10 acid was identified in the acidic fraction of sewage and sludge from the Iona Island Sewage Treatment Plant, British Columbia(7). Groundwater samples contaminated by industrial pollution near Barcelona, Spain were found to contain Multisol C10 acid at concns ranging from <5 to 27 ng/L(8). Food Survey Values Multisol C10 acid was identified as a volatile component of raw beef(1). Multisol C10 acid has been identified as a volatile flavor component of mutton and beef(2). Multisol C10 acid was a volatile constituent detected in strawberry jam at a concn of 2.9 mg/kg(3). Multisol C10 acid was found in popcorn using wet extraction method at 19 ug/kg(4). Multisol C10 acid was found as a volatile component of raw and roasted earth-almond (Cyperus esculentus l.). NIOSH (NOES Survey 1981-1983) has statistically estimated that 222,149 workers (8,182 of these were female) were potentially exposed to Multisol C10 acid in the US(1). Occupational exposure to Multisol C10 acid may occur through inhalation and dermal contact with this compound at workplaces where Multisol C10 acid is produced or used. Monitoring data indicate that the general population may be exposed to Multisol C10 acid via inhalation of ambient air, ingestion of food and drinking water, and dermal contact with this compound and other products containing Multisol C10 acid(SRC).
MULTISOL C8 ACID
Multisol C8 Acid Multisol C8 acid (from the Latin word capra, meaning "goat"), also known under the systematic name octanoic acid, is a saturated fatty acid and carboxylic acid with the structural formula CH3(CH2)6CO2H. It is a colorless oily liquid that is minimally soluble in water with a slightly unpleasant rancid-like smell and taste.[1] Salts and esters of octanoic acid are known as octanoates or caprylates. It is a common industrial chemical, which is produced by oxidation of the C8 aldehyde.[4] Its compounds are found naturally in the milk of various mammals and as a minor constituent of coconut oil and palm kernel oil. Two other acids are named after goats via the Latin word capra: caproic acid (C6) and capric acid (C10). Together, these three fatty acids comprise 15% of the fatty acids in goat milk fat. Uses of Multisol C8 acid Multisol C8 acid is used commercially in the production of esters used in perfumery and also in the manufacture of dyes. Multisol C8 acid is an antimicrobial pesticide used as a food contact surface sanitizer in commercial food handling establishments on dairy equipment, food processing equipment, breweries, wineries, and beverage processing plants. It is also used as disinfectant in health care facilities, schools/colleges, animal care/veterinary facilities, industrial facilities, office buildings, recreational facilities, retail and wholesale establishments, livestock premises, restaurants, and hotels/motels. In addition, Multisol C8 acid is used as an algicide, bactericide, fungicide, and herbicide in nurseries, greenhouses, garden centers, and interiors, and on ornamentation. Products containing Multisol C8 acid are formulated as soluble concentrate/liquids and ready-to-use liquids. Multisol C8 acid plays an important role in the body's regulation of energy input and output, a function which is performed by the hormone ghrelin. The sensation of hunger is a signal that the body requires an input of energy in the form of food consumption. Ghrelin stimulates hunger by triggering receptors in the hypothalamus. In order to activate these receptors, ghrelin must undergo a process called acylation in which it acquires an -OH group, and Multisol C8 acid provides this by linking at a specific site on ghrelin molecules. Other fatty acids in the same position have similar effects on hunger. Multisol C8 acid is currently being researched as a treatment for essential tremor. The acid chloride of Multisol C8 acid is used in the synthesis of perfluorooctanoic acid. Dietary uses of Multisol C8 acid See also: Medium-chain triglyceride § Dietary relevance Multisol C8 acid is taken as a dietary supplement. In the body, Multisol C8 acid would be found as octanoate, or unprotonated Multisol C8 acid. Some studies have shown that medium-chain triglycerides (MCTs) can help in the process of excess calorie burning, and thus weight loss; however, a systematic review of the evidence concluded that the overall results are inconclusive.[14] Also, interest in MCTs has been shown by endurance athletes and the bodybuilding community, but MCTs have not been found to be beneficial to improved exercise performance. Multisol C8 acid has been studied as part of a ketogenic diet to treat children with intractable epilepsy. A simple methodology for hyperimmune horse plasma fractionation, based on Multisol C8 acid precipitation, is described. Optimal conditions for fractionation were studied; the method gives best results when concentrated Multisol C8 acid was added to plasma, whose pH had been adjusted to 5.8, until a final Multisol C8 acid concentration of 5% was reached. The mixture was vigorously stirred during Multisol C8 acid addition and then for 60 min; afterwards the mixture was filtered. Non-immunoglobulin proteins precipitated in these conditions, whereas a highly enriched immunoglobulin preparation was obtained in the filtrate, which was then dialysed to remove Multisol C8 acid before the addition of sodium chloride and phenol. Thus, antivenon was produced after a single precipitation step followed by dialysis. In order to compare this methodology with that based on ammonium sulfate fractionation, a sample of hyperimmune plasma was divided into two aliquots which were fractionated in parallel by both methods. It was found that Multisol C8 acid-fractionated antivenom was superior in terms of yield, production time, albumin/globulin ratio, turbidity, protein aggregates, electrophoretic pattern and neutralizing potency against several activities of Bothrops asper venom. Owing to its efficacy and simplicity, this method could be of great value in antivenom and antitoxin production laboratories. Multisol C8 acid administered to rats is readily metabolized by the liver and many other tissues, forming carbon dioxide and two-carbon fragments, which are incorporated into long-chain fatty acids, as well as other water-soluble products. Multisol C8 acid is a food additive permitted for direct addition to food for human consumption, as long as 1) the quantity of the substance added to food does not exceed the amount reasonably required to accomplish its intended physical, nutritive, or other technical effect in food, and 2) any substance intended for use in or on food is of appropriate food grade and is prepared and handled as a food ingredient. Distillation Range (°C) Boiling Point 240 Flash Point (°C) 1<30 Purity (%m/m) C8 @ Min 98 Density (@ 20°C)(*@15°C) 0.900 Multisol C8 acid appears as a colorless to light yellow liquid with a mild odor. Burns, but may be difficult to ignite. Corrosive to metals and tissue. Children who suffer from seizures which are not controllable by drugs have apparently been successfully treated with MCT (medium chain triglyceride) diet. The MCT diet is an emulsion containing primarily (81%) Multisol C8 acid, but also contains 15% decanoic acid Multisol C8 acid is a saturated medium-chain fatty acid with an 8-carbon backbone. Multisol C8 acid is found naturally in the milk of various mammals and is a minor component of coconut oil and palm kernel oil. Children who suffer from seizures which are not controllable by drugs have apparently been successfully treated with MCT (medium chain triglyceride) diet. The MCT diet is an emulsion containing primarily (81%) Multisol C8 acid, but also contains 15% decanoic acid. In this study 15 children were receiving 50 to 60% of their energy requirement s from the MCT emulsion. Blood samples were analyzed for decanoic and Multisol C8 acid levels. There was a wide variation in absolute levels, possibly due to poor patient compliance, but all patients showed low levels in the mornings, rising to high levels in the evenings. This suggested that both acids are rapidly metabolized. To assess the disposition kinetics of selected structural analogs of valproic acid, the pharmacokinetics of valproic acid and 3 structural analogs, cyclohexanecarboxylic acid, l-methyl-l-cyclohexanecarboxylic acid (1-methylcyclohexanecarboxylic acid; and Multisol C8 acid were examined in female rats. All 4 carboxylic acids evidenced dose-dependent disposition. A dose-related decrease in total body clearance was observed for each compound, suggesting saturable eiminination processes. The apparent volume of distribution for these compounds was, with the exception of cyclohexanecarboxylic acid, dose-dependent, indicating that binding to proteins in serum and/or tissues may be saturable. Both valproic acid and 1-methylcyclohexanecarboxylic acid exhibited enterohepatic recirculation, which appeared to be dose- and compound-dependent. Significant quantities of both valproic acid and 1-methylcyclohexanecarboxylic acid were excreted in the urine as conjugates. Multisol C8 acid and cyclohexanecarboxylic acid were not excreted in the urine and did not evidence enterohepatic recirculation. It was concluded that minor changes in chemical structure of low molecular weight carboxylic acids have an influence on their metabolism and disposition. For Multisol C8 acid (USEPA/OPP Pesticide Code:128919) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses. Multisol C8 acid is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and/or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B; 51FR21438). Daily application of 7.2% Multisol C8 acid in propanol under cover to the skin of 10 volunteers caused redness in 4 subjects after 2 days and in 8 after 6 days. Multisol C8 acid and its sodium and potassium salts caused skin irritation in man and the acid was an eye irritant in rabbits. Cytochrome oxidase activity was investigated histochemically in the choroid plexus epithelium. Intense staining for the enzyme was exclusively limited to the mitochondria. Rats treated with Multisol C8 acid displayed extensive ultrastructural disruptions in the epithelial cells of the choroid plexus. Mitochondria were fewer in number and more disrupted compared to the control. The enzyme activity was greatly reduced. However, pretreatment with an equimolar dose of L-carnitine followed by Multisol C8 acid injection produced little alteration of either ultrastructure or enzyme staining. This study suggests that L-carnitine supplementation may restore mitochondrial function of the choroid plexus subjected to toxic organic anions in metabolic disorders, and may be useful in the prevention of metabolic encephalopathy. HUMAN EXPOSURE STUDIES/ In 25 subjects, covered contact with 1% Multisol C8 acid in petrolatum for 48 hr was not irritating. The medium chain fatty acid Multisol C8 acid was injected i.p. into 20-22 g Swiss-Albino mice at a dose of 15 umol/g. This dose produced a reproducible response consisting of a 3-4 min period of drowsiness, followed by coma. These mice as well as suitable controls were sacrificed by rapid submersion in liquid N2, or by microwave irradiation in a 7.3 kW microwave oven. Tissue from the reticular formation and the inferior colliculus was prepared for microanalysis of the energy metabolites glucose, glycogen, ATP and phosphocreatine. Results from this study showed a selective effect on energy metabolism in cells of the reticular formation. Both glucose and glycogen were elevated in the coma and precoma state. In addition, ATP and phosphocreatine were decreased in the reticular formation during coma. These results show a selective effect of Multisol C8 acid on energy metabolism in the reticular formation both in the precoma stage, and during overt coma. Multisol C8 acid's production and use in the synthesis of various dyes, drugs, perfumes, antiseptics and fungicides, in ore separations, synthetic flavors, hydraulic fluids, machining oils, flotation agents, and as a wood preservative may result in its release to the environment through various waste streams. Multisol C8 acid is a fatty acid and is widely distributed in nature as a component of animal and vegetable fats. Fatty acids are an important part of the normal daily diet of mammals, birds and invertebrates. Multisol C8 acid can occur naturally in essential oils and in cow milk fat. If released to air, a vapor pressure of 3.71X10-3 mm Hg at 25 °C indicates Multisol C8 acid will exist solely as a vapor in the atmosphere. Vapor-phase Multisol C8 acid will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 1.9 days. If released to soil, undissociated Multisol C8 acid is expected to have low mobility based upon an estimated Koc of 1,100 for the free acid. The pKa of Multisol C8 acid is 4.89, indicating that this compound will exist almost entirely in anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts. Volatilization from moist soil surfaces is not expected to be an important fate process based upon the pKa. Biodegradation of Multisol C8 acid in soil and water is expected to be an important fate process; Multisol C8 acid reached 32.8% of its theoretical oxygen demand after 24 hours using an activated sludge inoculum. If released into water, undissociated Multisol C8 acid is expected to adsorb to suspended solids and sediment based upon the estimated Koc for the free acid. Volatilization from water surfaces is not expected to be an important fate process based on the pKa. An estimated BCF of 3 suggests the potential for bioconcentration in aquatic organisms is low. Hydrolysis is not expected to be an important environmental fate process since this compound lacks functional groups that hydrolyze under environmental conditions. Occupational exposure to Multisol C8 acid may occur through inhalation and dermal contact with this compound at workplaces where Multisol C8 acid is produced or used. Monitoring data indicate that the general population may be exposed to Multisol C8 acid via inhalation of ambient air, ingestion of food and drinking water, and dermal contact with this compound and other products containing Multisol C8 acid. The Multisol C8 acid content in milk fat of cows ranges from 0.53 to 1.04% of total fatty acids, with an average Multisol C8 acid content of 0.79% of total fatty acids(1). The compound is a carboxylic acid that is also known as a fatty acid because fatty acids were first isolated by the hydrolysis of naturally occurring fats(2). Fatty acids are widely distributed in nature as components of animal and vegetable fats(3) including lipids such as oils and fats, waxes, sterol esters and other minor compounds(2). Multisol C8 acid's production and use in the synthesis of various dyes, drugs, perfumes, antiseptics and fungicides, in ore separations, synthetic flavors(1), hydraulic fluids, machining oils, flotation agents, and as a wood preservative(2) may result in its release to the environment through various waste streams(SRC). TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 1,100 for the free acid(SRC), determined from a log Kow of 3.05(2) and a regression-derived equation(3), indicates that undissociated Multisol C8 acid is expected to have low mobility in soil(SRC). The pKa of Multisol C8 acid is 4.89(4), indicating that this compound will exist almost entirely in anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5). Volatilization of Multisol C8 acid from moist soil is not expected to be an important fate process because the acid is in the anion form and anions do not volatilize(SRC). Multisol C8 acid is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 3.71X10-3 mm Hg(6). In Warburg respirometer tests using an activated sludge seed, Multisol C8 acid reached 9.8, 20.4, and 32.8% of its theoretical oxygen demand after 6, 12, and 24 hours incubation, respectively(7), suggesting that biodegradation may be an important environmental fate process in soil(SRC). AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 1,100 for the free acid(SRC), determined from a log Kow of 3.05(2) and a regression-derived equation(3), indicates that undissociated Multisol C8 acid is expected to adsorb to suspended solids and sediment(SRC). A pKa of 4.89(4) indicates Multisol C8 acid will exist almost entirely in the anion form at pH values of 5 to 9 and therefore volatilization from water surfaces is not expected to be an important fate process(5). According to a classification scheme(6), an estimated BCF of 3(SRC), from its log Kow(2) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). In Warburg respirometer tests using an activated sludge seed, Multisol C8 acid reached 9.8, 20.4, and 32.8% of its theoretical oxygen demand after 6, 12, and 24 hours incubation, respectively(8), suggesting that biodegradation may be an important environmental fate process in water(SRC). ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), Multisol C8 acid, which has a vapor pressure of 3.71X10-3 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase Multisol C8 acid is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 1.9 days(SRC), calculated from its rate constant of 8.3X10-12 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Multisol C8 acid does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(4). AEROBIC: Multisol C8 acid reached 43, 53, 64 and 63% of its theoretical BOD after 2, 5, 10, and 30 days, respectively using a domestic sewage inoculum and an Multisol C8 acid concn of 3.0 ppm(1). 100% decreases in initial Multisol C8 acid concns of 0.5 mg/L and 4.3 mg/L were observed after 21 days incubation in aerobic mixed bacterial cultures obtained from trench leachate at low-level radioactive waste disposal sites in Maxey Flats, KY and West Valley, NY, respectively(2). Multisol C8 acid reached 60% of its theoretical oxygen demand after 5 days using a sewage seed(3). After a lag period of 2.2 days, Multisol C8 acid present at a concn of 10,000 ppm, reached 60, 66, and 68% of its theoretical BOD after 5, 10, and 20 days, respectively using a sewage seed(4). Use of an adapted sewage seed reduced the lag period to 1.6 days, after which Multisol C8 acid reached 60, 69, and 70% of its theoretical BOD after 5, 10, and 20 days, respectively(4). In Warburg respirometer tests using an activated sludge seed, Multisol C8 acid, present at a concn of 500 ppm, reached 9.8, 20.4, and 32.8% of its theoretical oxygen demand after 6, 12, and 24 hours incubation, respectively(5). After 24 hours incubation, Multisol C8 acid, present at a concn of 500 ppm, reached 5 and 59% of its theoretical oxygen demand using activated sludge inoculum from two different municipal sources(5). In a Warburg test using an activated sludge inoculum acclimated to phenol, Multisol C8 acid, present at a concn of 500 ppm, reached 20% of its theoretical BOD after 12 hours(6). Two bacterial soil isolants were able to utilize octanoate as a growth substrate(7). A total organic carbon removal ratio of 97% was observed for Multisol C8 acid using a non-acclimated activated sludge and an initial Multisol C8 acid concn of 100 mg total organic carbon/L(8). The rate constant for the vapor-phase reaction of Multisol C8 acid with photochemically-produced hydroxyl radicals has been estimated as 8.3X10-12 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 1.9 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). Multisol C8 acid is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(2). Multisol C8 acid does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(3). The Koc of undissociated Multisol C8 acid is estimated as 1,100 for the free acid(SRC), using a log Kow of 3.05(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that undissociated Multisol C8 acid is expected to have low mobility in soil. The pKa of Multisol C8 acid is 4.89(4), indicating that this compound will exist almost entirely in the anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5). Multisol C8 acid was detected in aqueous industrial effluent extracts collected between Nov 1979-81 in the following industrial categories (concentration in one effluent extract): paint and ink (119 ng/uL); printing and publishing (279 ng/uL); ore mining (43 ng/uL); organics and plastics (266 ng/uL); pulp and paper (399 ng/uL); rubber processing (1511 ng/uL); auto and other laundries (139 ng/uL); electronics (114 ng/uL); mechanical products (4976 ng/uL); and publicly owned treatment works at an unknown concn(1). Multisol C8 acid was detected in the leachate of a sanitary landfill located in Barcelona, Spain at an unreported concn(2). Oil shale retort water from the Kerosene Creek seam of the Rundle deposit, Queensland, Australia, was found to contain Multisol C8 acid at a concn of 270 mg/L(3). Multisol C8 acid was detected in groundwater from a landfill well near Norman, OK at an estimated concn of 0.6 ug/L(4). A grab sample, obtained in April 1980, of the final effluent from the Addison, IL Publicly Owned Treatment Works was found to contain Multisol C8 acid at an unreported concn(5). Multisol C8 acid was detected in Los Angeles County wastewater treatment plant effluent, collected between Nov 1980 and Aug 1981, at a concn of 400 ug/L(6). Multisol C8 acid was identified in the acidic fraction of sewage and sludge from the Iona Island Sewage Treatment Plant, British Columbia(7). Groundwater samples contaminated by industrial pollution near Barcelona, Spain were found to contain Multisol C8 acid at concns ranging from <5 to 27 ng/L(8). Food Survey Values Multisol C8 acid was identified as a volatile component of raw beef(1). Multisol C8 acid has been identified as a volatile flavor component of mutton and beef(2). Multisol C8 acid was a volatile constituent detected in strawberry jam at a concn of 2.9 mg/kg(3). Multisol C8 acid was found in popcorn using wet extraction method at 19 ug/kg(4). Multisol C8 acid was found as a volatile component of raw and roasted earth-almond (Cyperus esculentus l.). NIOSH (NOES Survey 1981-1983) has statistically estimated that 222,149 workers (8,182 of these were female) were potentially exposed to Multisol C8 acid in the US(1). Occupational exposure to Multisol C8 acid may occur through inhalation and dermal contact with this compound at workplaces where Multisol C8 acid is produced or used. Monitoring data indicate that the general population may be exposed to Multisol C8 acid via inhalation of ambient air, ingestion of food and drinking water, and dermal contact with this compound and other products containing Multisol C8 acid(SRC). Benefits of Multisol C8 acid (caprylic acid) Multisol C8 acid (caprylic acid) is one of the three fatty acids found in coconut oil. It’s a medium-chain fatty acid with potent antibacterial, antifungal, and anti-inflammatory properties. These properties make Multisol C8 acid (caprylic acid) a helpful treatment for many conditions. It’s used to treat yeast infections, skin conditions, digestive disorders, and high cholesterol. It’s also used to lower the risk of antibiotic resistance. You can take Multisol C8 acid (caprylic acid) orally or apply it to your skin. Yeast infections Candida yeast infections are a common medical problem. Candida infections are fungal infections. They can cause vaginal yeast infections, nail fungus, and oral thrush. The antifungal properties of Multisol C8 acid (caprylic acid) are thought to kill and reduce yeast. A 2011 studyTrusted Source found that Multisol C8 acid (caprylic acid) was effective in treating some candida infections. Some scientists believe that Multisol C8 acid (caprylic acid) is so effective because it can break down the membranes of candida cells. A procedure called oil pulling is sometimes used as a remedy for oral thrush. Oil pulling involves swishing coconut oil in the mouth for 10 to 20 minutes at a time. Ingesting a tablespoon or two a day can also help combat yeast infections that occur within the body. Skin conditions Just as Multisol C8 acid (caprylic acid) can treat yeast infections, it can also help treat certain skin conditions. This is largely thanks to its antibacterial and antimicrobial properties. These help it kill off bacteria that live in the skin. Dermatophilosis is a skin condition caused by a bacterial infection that can result in painful, dry scabs. One natural remedy involves applying coconut oil directly to the affect areas. This can help fight off the bacterial infection and soothe the dry skin. Multisol C8 acid (caprylic acid) is also thought to help treat one of the most common skin conditions of all: acne. Coconut oil is often used as a homeopathic acne treatment. This is because it can fight the bacterial infections that sometimes cause acne. A 2014 studyTrusted Source found that Multisol C8 acid (caprylic acid) is effective at treating acne thanks to its antimicrobial and antibacterial properties. Multisol C8 acid (caprylic acid) is sometimes also used as a natural remedy for conditions like eczema or psoriasis. Digestive disorders There is some evidence that Multisol C8 acid (caprylic acid) can help patients who have certain digestive disorders. The anti-inflammatory and antibacterial properties of Multisol C8 acid (caprylic acid) can help treat conditions like inflammatory bowel disorder or irritable bowel syndrome. Both of these conditions involve inflammation and sometimes bacterial infections in the digestive system. The antibacterial properties may also help patients with Crohn’s or ulcerative colitis. Consult your doctor before using Multisol C8 acid (caprylic acid) or coconut oil to treat a digestive disorder. Both can sometimes cause stomach upset. Antibiotic resistance Antibiotic resistance is a growing problem around the world. Multisol C8 acid (caprylic acid) can potentially help lower the risk of antibiotic resistance. Doctors may be able to avoid prescribing antibiotics by treating some bacterial infections with coconut oil or Multisol C8 acid (caprylic acid). This approach could help defeat bacteria without strengthening it through antibiotic exposure. A 2005 studyTrusted Source found that Multisol C8 acid (caprylic acid) was successful in reducing five different types of bacteria in contaminated milk, including E. coli. The study recommended considering Multisol C8 acid (caprylic acid) as an alternative treatment for bacterial infections. Cholesterol Multisol C8 acid (caprylic acid) is a medium-chain fatty acid. These fatty acids have been proven to have a positive effect on lowering high cholesterol. A 2006 animal studyTrusted Source found that the subjects that were fed structured triglyceride oils had lower blood cholesterol levels and lower aortic accumulation of cholesterol than those who were not. A 2013 study supported these findings. Those given Multisol C8 acid (caprylic acid) reported unaffected HDL, or “good” cholesterol levels. They also reported lower levels of LDL, or “bad” cholesterol. How to get Multisol C8 acid (caprylic acid) You can reap the benefits of Multisol C8 acid (caprylic acid) by ingesting coconut oil or applying it to the skin. Start by adding one tablespoon or less of coconut oil to your diet a day to make sure you can tolerate it. People ingest coconut oil as is or melted. You can also add it to other foods. Try blending it into a smoothie! Working coconut oil into your diet is generally a safe way to help you reap the benefits of Multisol C8 acid (caprylic acid). Coconut oil is one of the more popular ways to get your daily dose of Multisol C8 acid (caprylic acid). There are several other options. Palm oil and human breast milk both contain Multisol C8 acid (caprylic acid). Multisol C8 acid (caprylic acid) is also available in supplement form. It can be found in vitamin shops, some health food stores, or online. What is Multisol C8 acid? Multisol C8 acid is a medium-chain fatty acid that is found in palm oil, coconut oil, and the milk of humans and bovines. Multisol C8 acid is taken by mouth for epilepsy (seizures), low levels of the blood protein albumin in people undergoing dialysis, digestive disorders such as dysbiosis (abnormal levels of bacteria in the stomach), abnormal absorption of fats, and chylothorax (leakage of a substance called chyle into the chest cavity). When taken as part of a ketogenic or medium-chain triglyceride (MCT) diet, Multisol C8 acid seems to help reduce the number of seizures in people with epilepsy. However, side effects and difficulty following the diet seem to limit its long-term use. More evidence is needed to rate Multisol C8 acid for this use. How does Multisol C8 acid work? Multisol C8 acid might lower blood pressure in some people. It can also be given to people as part of a test used to measure gastric emptying. Are there safety concerns? Multisol C8 acid is LIKELY SAFE for most people when taken by mouth in food amounts or when used at approved doses for nutritional supplementation and in tests to measure stomach emptying. It can cause some side effects, including nausea, bloating, and diarrhea. Multisol C8 acid is POSSIBLY SAFE when taken by mouth as part of a ketogenic diet or a diet high in medium chain triglycerides (MCTs) under the guidance of a physician. However, diets containing high amounts of Multisol C8 acid might cause constipation, vomiting, stomach pain, low levels of calcium in the blood, drowsiness, or growth problems. Multisol C8 acid is LIKELY UNSAFE when taken by mouth by people with a condition known as medium-chain acyl-CoA dehydrogenase (MCAD) deficiency. People with this condition are not able to break down Multisol C8 acid appropriately. This can lead to increased levels of Multisol C8 acid in the blood, which may increase the risk of comas. Special Precautions & Warnings: Pregnancy and breast-feeding: Not enough is known about the use of Multisol C8 acid during pregnancy and breast-feeding. Stay on the safe side and avoid use. Liver disease: Multisol C8 acid is broken down by the liver. There is some concern that people with liver disease might not be able to break down Multisol C8 acid. This might cause blood levels of Multisol C8 acid to increase. However, other research suggests that people with liver disease are still able to break down Multisol C8 acid. Until more is known, use with caution. Low blood pressure (hypotension): Multisol C8 acid can lower blood pressure. In theory, Multisol C8 acid might cause blood pressure to go too low if used by people prone to low blood pressure. Use with caution. Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency: People with MCAD deficiency are not able to break down Multisol C8 acid appropriately. This can lead to increased levels of Multisol C8 acid in the blood, which might increase the risk of comas. Avoid using. Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency: People with MCAD deficiency are not able to break down Multisol C8 acid appropriately. This can lead to increased levels of Multisol C8 acid in the blood, which might increase the risk of comas. Avoid using.
MULTISOL ISO-C9 ACID
Multisol Iso-C9 Acid Multisol iso-C9 acid, also called nonanoic acid, is an organic compound with structural formula CH3(CH2)7CO2H. It is a nine-carbon fatty acid. Nonanoic acid is a colorless oily liquid with an unpleasant, rancid odor. It is nearly insoluble in water, but very soluble in organic solvents. The esters and salts of Multisol iso-C9 acid are called pelargonates or nonanoates. Preparation, occurrence, and uses Multisol iso-C9 acid occurs naturally as esters in the oil of pelargonium. Together with azelaic acid, it is produced industrially by ozonolysis of oleic acid. H17C9CH=CHC7H14CO2H + 4O → HO2CC7H14CO2H + H17C9CO2H Synthetic esters of Multisol iso-C9 acid, such as methyl pelargonate, are used as flavorings. Multisol iso-C9 acid is also used in the preparation of plasticizers and lacquers. The derivative 4-nonanoylmorpholine is an ingredient in some pepper sprays. The ammonium salt of Multisol iso-C9 acid, ammonium pelargonate, is an herbicide. It is commonly used in conjunction with glyphosate, a non-selective herbicide, for a quick burn-down effect in the control of weeds in turfgrass. Pharmacological effects Multisol iso-C9 acid may be more potent than valproic acid in treating seizures.[3] Moreover, in contrast to valproic acid, Multisol iso-C9 acid exhibited no effect on HDAC inhibition, suggesting that it is unlikely to show HDAC inhibition-related teratogenicity. Taste Description:fatty Multisol iso-C9 acid is one of the acids mainly responsible for the so-called "soo" odour of mutton. The analogue 4-Ethyloctanoic acid (found in Virginia tobacco and Costus root oil) also has a related goaty odor; this analog has the lowest threshold of all the fatty acids at 1.8 ppb. Multisol iso-C9 acid is used in flavours for cheese, meat, tobacco and (possibly) fish. Normal use levels in finished consumer product: up to 3 ppm. Distillation Range (°C) Boiling Point 235 Flash Point (°C) 120 Purity (%m/m) C9’s @ min 99 Density (@ 20°C)(*@15°C) 0.899 Multisol iso-C9 acid plays an important role in the body's regulation of energy input and output, a function which is performed by the hormone ghrelin. The sensation of hunger is a signal that the body requires an input of energy in the form of food consumption. Ghrelin stimulates hunger by triggering receptors in the hypothalamus. In order to activate these receptors, ghrelin must undergo a process called acylation in which it acquires an -OH group, and Multisol iso-C9 acid provides this by linking at a specific site on ghrelin molecules. Other fatty acids in the same position have similar effects on hunger. Multisol iso-C9 acid is currently being researched as a treatment for essential tremor. The acid chloride of Multisol iso-C9 acid is used in the synthesis of perfluorooctanoic acid. Dietary uses of Multisol iso-C9 acid See also: Medium-chain triglyceride § Dietary relevance Multisol iso-C9 acid is taken as a dietary supplement. In the body, Multisol iso-C9 acid would be found as octanoate, or unprotonated Multisol iso-C9 acid. Some studies have shown that medium-chain triglycerides (MCTs) can help in the process of excess calorie burning, and thus weight loss; however, a systematic review of the evidence concluded that the overall results are inconclusive.[14] Also, interest in MCTs has been shown by endurance athletes and the bodybuilding community, but MCTs have not been found to be beneficial to improved exercise performance. Multisol iso-C9 acid has been studied as part of a ketogenic diet to treat children with intractable epilepsy. How to get Multisol iso-C9 acid You can reap the benefits of Multisol iso-C9 acid by ingesting coconut oil or applying it to the skin. Start by adding one tablespoon or less of coconut oil to your diet a day to make sure you can tolerate it. People ingest coconut oil as is or melted. You can also add it to other foods. Try blending it into a smoothie! Working coconut oil into your diet is generally a safe way to help you reap the benefits of Multisol iso-C9 acid . Coconut oil is one of the more popular ways to get your daily dose of Multisol iso-C9 acid . There are several other options. Palm oil and human breast milk both contain Multisol iso-C9 acid . Multisol iso-C9 acid is also available in supplement form. It can be found in vitamin shops, some health food stores, or online. What is Multisol iso-C9 acid? Multisol iso-C9 acid is a medium-chain fatty acid that is found in palm oil, coconut oil, and the milk of humans and bovines. Multisol iso-C9 acid is taken by mouth for epilepsy (seizures), low levels of the blood protein albumin in people undergoing dialysis, digestive disorders such as dysbiosis (abnormal levels of bacteria in the stomach), abnormal absorption of fats, and chylothorax (leakage of a substance called chyle into the chest cavity). When taken as part of a ketogenic or medium-chain triglyceride (MCT) diet, Multisol iso-C9 acid seems to help reduce the number of seizures in people with epilepsy. However, side effects and difficulty following the diet seem to limit its long-term use. More evidence is needed to rate Multisol iso-C9 acid for this use. Are there safety concerns? Multisol iso-C9 acid is LIKELY SAFE for most people when taken by mouth in food amounts or when used at approved doses for nutritional supplementation and in tests to measure stomach emptying. It can cause some side effects, including nausea, bloating, and diarrhea. Multisol iso-C9 acid is POSSIBLY SAFE when taken by mouth as part of a ketogenic diet or a diet high in medium chain triglycerides (MCTs) under the guidance of a physician. However, diets containing high amounts of Multisol iso-C9 acid might cause constipation, vomiting, stomach pain, low levels of calcium in the blood, drowsiness, or growth problems. Multisol iso-C9 acid is LIKELY UNSAFE when taken by mouth by people with a condition known as medium-chain acyl-CoA dehydrogenase (MCAD) deficiency. People with this condition are not able to break down Multisol iso-C9 acid appropriately. This can lead to increased levels of Multisol iso-C9 acid in the blood, which may increase the risk of comas. Special Precautions & Warnings: Pregnancy and breast-feeding: Not enough is known about the use of Multisol iso-C9 acid during pregnancy and breast-feeding. Stay on the safe side and avoid use. Liver disease: Multisol iso-C9 acid is broken down by the liver. There is some concern that people with liver disease might not be able to break down Multisol iso-C9 acid. This might cause blood levels of Multisol iso-C9 acid to increase. However, other research suggests that people with liver disease are still able to break down Multisol iso-C9 acid. Until more is known, use with caution. Low blood pressure (hypotension): Multisol iso-C9 acid can lower blood pressure. In theory, Multisol iso-C9 acid might cause blood pressure to go too low if used by people prone to low blood pressure. Use with caution. Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency: People with MCAD deficiency are not able to break down Multisol iso-C9 acid appropriately. This can lead to increased levels of Multisol iso-C9 acid in the blood, which might increase the risk of comas. Avoid using. Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency: People with MCAD deficiency are not able to break down Multisol iso-C9 acid appropriately. This can lead to increased levels of Multisol iso-C9 acid in the blood, which might increase the risk of comas. Avoid using. A simple methodology for hyperimmune horse plasma fractionation, based on Multisol iso-C9 acid precipitation, is described. Optimal conditions for fractionation were studied; the method gives best results when concentrated Multisol iso-C9 acid was added to plasma, whose pH had been adjusted to 5.8, until a final Multisol iso-C9 acid concentration of 5% was reached. The mixture was vigorously stirred during Multisol iso-C9 acid addition and then for 60 min; afterwards the mixture was filtered. Non-immunoglobulin proteins precipitated in these conditions, whereas a highly enriched immunoglobulin preparation was obtained in the filtrate, which was then dialysed to remove Multisol iso-C9 acid before the addition of sodium chloride and phenol. Thus, antivenon was produced after a single precipitation step followed by dialysis. In order to compare this methodology with that based on ammonium sulfate fractionation, a sample of hyperimmune plasma was divided into two aliquots which were fractionated in parallel by both methods. It was found that Multisol iso-C9 acid-fractionated antivenom was superior in terms of yield, production time, albumin/globulin ratio, turbidity, protein aggregates, electrophoretic pattern and neutralizing potency against several activities of Bothrops asper venom. Owing to its efficacy and simplicity, this method could be of great value in antivenom and antitoxin production laboratories. Multisol iso-C9 acid administered to rats is readily metabolized by the liver and many other tissues, forming carbon dioxide and two-carbon fragments, which are incorporated into long-chain fatty acids, as well as other water-soluble products. Multisol iso-C9 acid is a food additive permitted for direct addition to food for human consumption, as long as 1) the quantity of the substance added to food does not exceed the amount reasonably required to accomplish its intended physical, nutritive, or other technical effect in food, and 2) any substance intended for use in or on food is of appropriate food grade and is prepared and handled as a food ingredient. Children who suffer from seizures which are not controllable by drugs have apparently been successfully treated with MCT (medium chain triglyceride) diet. The MCT diet is an emulsion containing primarily (81%) Multisol iso-C9 acid, but also contains 15% decanoic acid. In this study 15 children were receiving 50 to 60% of their energy requirement s from the MCT emulsion. Blood samples were analyzed for decanoic and Multisol iso-C9 acid levels. There was a wide variation in absolute levels, possibly due to poor patient compliance, but all patients showed low levels in the mornings, rising to high levels in the evenings. This suggested that both acids are rapidly metabolized. To assess the disposition kinetics of selected structural analogs of valproic acid, the pharmacokinetics of valproic acid and 3 structural analogs, cyclohexanecarboxylic acid, l-methyl-l-cyclohexanecarboxylic acid (1-methylcyclohexanecarboxylic acid; and Multisol iso-C9 acid were examined in female rats. All 4 carboxylic acids evidenced dose-dependent disposition. A dose-related decrease in total body clearance was observed for each compound, suggesting saturable eiminination processes. The apparent volume of distribution for these compounds was, with the exception of cyclohexanecarboxylic acid, dose-dependent, indicating that binding to proteins in serum and/or tissues may be saturable. Both valproic acid and 1-methylcyclohexanecarboxylic acid exhibited enterohepatic recirculation, which appeared to be dose- and compound-dependent. Significant quantities of both valproic acid and 1-methylcyclohexanecarboxylic acid were excreted in the urine as conjugates. Multisol iso-C9 acid and cyclohexanecarboxylic acid were not excreted in the urine and did not evidence enterohepatic recirculation. It was concluded that minor changes in chemical structure of low molecular weight carboxylic acids have an influence on their metabolism and disposition. Cytochrome oxidase activity was investigated histochemically in the choroid plexus epithelium. Intense staining for the enzyme was exclusively limited to the mitochondria. Rats treated with Multisol iso-C9 acid displayed extensive ultrastructural disruptions in the epithelial cells of the choroid plexus. Mitochondria were fewer in number and more disrupted compared to the control. The enzyme activity was greatly reduced. However, pretreatment with an equimolar dose of L-carnitine followed by Multisol iso-C9 acid injection produced little alteration of either ultrastructure or enzyme staining. This study suggests that L-carnitine supplementation may restore mitochondrial function of the choroid plexus subjected to toxic organic anions in metabolic disorders, and may be useful in the prevention of metabolic encephalopathy. TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 1,100 for the free acid(SRC), determined from a log Kow of 3.05(2) and a regression-derived equation(3), indicates that undissociated Multisol iso-C9 acid is expected to have low mobility in soil(SRC). The pKa of Multisol iso-C9 acid is 4.89(4), indicating that this compound will exist almost entirely in anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5). Volatilization of Multisol iso-C9 acid from moist soil is not expected to be an important fate process because the acid is in the anion form and anions do not volatilize(SRC). Multisol iso-C9 acid is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 3.71X10-3 mm Hg(6). In Warburg respirometer tests using an activated sludge seed, Multisol iso-C9 acid reached 9.8, 20.4, and 32.8% of its theoretical oxygen demand after 6, 12, and 24 hours incubation, respectively(7), suggesting that biodegradation may be an important environmental fate process in soil(SRC). AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 1,100 for the free acid(SRC), determined from a log Kow of 3.05(2) and a regression-derived equation(3), indicates that undissociated Multisol iso-C9 acid is expected to adsorb to suspended solids and sediment(SRC). A pKa of 4.89(4) indicates Multisol iso-C9 acid will exist almost entirely in the anion form at pH values of 5 to 9 and therefore volatilization from water surfaces is not expected to be an important fate process(5). According to a classification scheme(6), an estimated BCF of 3(SRC), from its log Kow(2) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). In Warburg respirometer tests using an activated sludge seed, Multisol iso-C9 acid reached 9.8, 20.4, and 32.8% of its theoretical oxygen demand after 6, 12, and 24 hours incubation, respectively(8), suggesting that biodegradation may be an important environmental fate process in water(SRC). ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), Multisol iso-C9 acid, which has a vapor pressure of 3.71X10-3 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase Multisol iso-C9 acid is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 1.9 days(SRC), calculated from its rate constant of 8.3X10-12 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3). Multisol iso-C9 acid does not contain chromophores that absorb at wavelengths >290 nm and therefore is not expected to be susceptible to direct photolysis by sunlight(4). HUMAN EXPOSURE STUDIES/ In 25 subjects, covered contact with 1% Multisol iso-C9 acid in petrolatum for 48 hr was not irritating. The medium chain fatty acid Multisol iso-C9 acid was injected i.p. into 20-22 g Swiss-Albino mice at a dose of 15 umol/g. This dose produced a reproducible response consisting of a 3-4 min period of drowsiness, followed by coma. These mice as well as suitable controls were sacrificed by rapid submersion in liquid N2, or by microwave irradiation in a 7.3 kW microwave oven. Tissue from the reticular formation and the inferior colliculus was prepared for microanalysis of the energy metabolites glucose, glycogen, ATP and phosphocreatine. Results from this study showed a selective effect on energy metabolism in cells of the reticular formation. Both glucose and glycogen were elevated in the coma and precoma state. In addition, ATP and phosphocreatine were decreased in the reticular formation during coma. These results show a selective effect of Multisol iso-C9 acid on energy metabolism in the reticular formation both in the precoma stage, and during overt coma. Food Survey Values Multisol iso-C9 acid was identified as a volatile component of raw beef(1). Multisol iso-C9 acid has been identified as a volatile flavor component of mutton and beef(2). Multisol iso-C9 acid was a volatile constituent detected in strawberry jam at a concn of 2.9 mg/kg(3). Multisol iso-C9 acid was found in popcorn using wet extraction method at 19 ug/kg(4). Multisol iso-C9 acid was found as a volatile component of raw and roasted earth-almond (Cyperus esculentus l.). NIOSH (NOES Survey 1981-1983) has statistically estimated that 222,149 workers (8,182 of these were female) were potentially exposed to Multisol iso-C9 acid in the US(1). Occupational exposure to Multisol iso-C9 acid may occur through inhalation and dermal contact with this compound at workplaces where Multisol iso-C9 acid is produced or used. Monitoring data indicate that the general population may be exposed to Multisol iso-C9 acid via inhalation of ambient air, ingestion of food and drinking water, and dermal contact with this compound and other products containing Multisol iso-C9 acid(SRC). Benefits of Multisol iso-C9 acid Multisol iso-C9 acid is one of the three fatty acids found in coconut oil. It’s a medium-chain fatty acid with potent antibacterial, antifungal, and anti-inflammatory properties. These properties make Multisol iso-C9 acid a helpful treatment for many conditions. It’s used to treat yeast infections, skin conditions, digestive disorders, and high cholesterol. It’s also used to lower the risk of antibiotic resistance. You can take Multisol iso-C9 acid orally or apply it to your skin. Yeast infections Candida yeast infections are a common medical problem. Candida infections are fungal infections. They can cause vaginal yeast infections, nail fungus, and oral thrush. The antifungal properties of Multisol iso-C9 acid are thought to kill and reduce yeast. A 2011 studyTrusted Source found that Multisol iso-C9 acid was effective in treating some candida infections. Some scientists believe that Multisol iso-C9 acid is so effective because it can break down the membranes of candida cells. A procedure called oil pulling is sometimes used as a remedy for oral thrush. Oil pulling involves swishing coconut oil in the mouth for 10 to 20 minutes at a time. Ingesting a tablespoon or two a day can also help combat yeast infections that occur within the body. Skin conditions Just as Multisol iso-C9 acid can treat yeast infections, it can also help treat certain skin conditions. This is largely thanks to its antibacterial and antimicrobial properties. These help it kill off bacteria that live in the skin. Dermatophilosis is a skin condition caused by a bacterial infection that can result in painful, dry scabs. One natural remedy involves applying coconut oil directly to the affect areas. This can help fight off the bacterial infection and soothe the dry skin. Multisol iso-C9 acid is also thought to help treat one of the most common skin conditions of all: acne. Coconut oil is often used as a homeopathic acne treatment. This is because it can fight the bacterial infections that sometimes cause acne. A 2014 studyTrusted Source found that Multisol iso-C9 acid is effective at treating acne thanks to its antimicrobial and antibacterial properties. Multisol iso-C9 acid is sometimes also used as a natural remedy for conditions like eczema or psoriasis. Digestive disorders There is some evidence that Multisol iso-C9 acid can help patients who have certain digestive disorders. The anti-inflammatory and antibacterial properties of Multisol iso-C9 acid can help treat conditions like inflammatory bowel disorder or irritable bowel syndrome. Both of these conditions involve inflammation and sometimes bacterial infections in the digestive system. The antibacterial properties may also help patients with Crohn’s or ulcerative colitis. Consult your doctor before using Multisol iso-C9 acid or coconut oil to treat a digestive disorder. Both can sometimes cause stomach upset. Antibiotic resistance Antibiotic resistance is a growing problem around the world. Multisol iso-C9 acid can potentially help lower the risk of antibiotic resistance. Doctors may be able to avoid prescribing antibiotics by treating some bacterial infections with coconut oil or Multisol iso-C9 acid . This approach could help defeat bacteria without strengthening it through antibiotic exposure. A 2005 studyTrusted Source found that Multisol iso-C9 acid was successful in reducing five different types of bacteria in contaminated milk, including E. coli. The study recommended considering Multisol iso-C9 acid as an alternative treatment for bacterial infections. Cholesterol Multisol iso-C9 acid is a medium-chain fatty acid. These fatty acids have been proven to have a positive effect on lowering high cholesterol. A 2006 animal studyTrusted Source found that the subjects that were fed structured triglyceride oils had lower blood cholesterol levels and lower aortic accumulation of cholesterol than those who were not. A 2013 study supported these findings. Those given Multisol iso-C9 acid reported unaffected HDL, or “good” cholesterol levels. They also reported lower levels of LDL, or “bad” cholesterol. Multisol iso-C9 acid's production and use in the synthesis of various dyes, drugs, perfumes, antiseptics and fungicides, in ore separations, synthetic flavors, hydraulic fluids, machining oils, flotation agents, and as a wood preservative may result in its release to the environment through various waste streams. Multisol iso-C9 acid is a fatty acid and is widely distributed in nature as a component of animal and vegetable fats. Fatty acids are an important part of the normal daily diet of mammals, birds and invertebrates. Multisol iso-C9 acid can occur naturally in essential oils and in cow milk fat. If released to air, a vapor pressure of 3.71X10-3 mm Hg at 25 °C indicates Multisol iso-C9 acid will exist solely as a vapor in the atmosphere. Vapor-phase Multisol iso-C9 acid will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 1.9 days. If released to soil, undissociated Multisol iso-C9 acid is expected to have low mobility based upon an estimated Koc of 1,100 for the free acid. The pKa of Multisol iso-C9 acid is 4.89, indicating that this compound will exist almost entirely in anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts. Volatilization from moist soil surfaces is not expected to be an important fate process based upon the pKa. Biodegradation of Multisol iso-C9 acid in soil and water is expected to be an important fate process; Multisol iso-C9 acid reached 32.8% of its theoretical oxygen demand after 24 hours using an activated sludge inoculum. If released into water, undissociated Multisol iso-C9 acid is expected to adsorb to suspended solids and sediment based upon the estimated Koc for the free acid. Volatilization from water surfaces is not expected to be an important fate process based on the pKa. An estimated BCF of 3 suggests the potential for bioconcentration in aquatic organisms is low. Hydrolysis is not expected to be an important environmental fate process since this compound lacks functional groups that hydrolyze under environmental conditions. Occupational exposure to Multisol iso-C9 acid may occur through inhalation and dermal contact with this compound at workplaces where Multisol iso-C9 acid is produced or used. Monitoring data indicate that the general population may be exposed to Multisol iso-C9 acid via inhalation of ambient air, ingestion of food and drinking water, and dermal contact with this compound and other products containing Multisol iso-C9 acid. The Multisol iso-C9 acid content in milk fat of cows ranges from 0.53 to 1.04% of total fatty acids, with an average Multisol iso-C9 acid content of 0.79% of total fatty acids(1). The compound is a carboxylic acid that is also known as a fatty acid because fatty acids were first isolated by the hydrolysis of naturally occurring fats(2). Fatty acids are widely distributed in nature as components of animal and vegetable fats(3) including lipids such as oils and fats, waxes, sterol esters and other minor compounds(2). Multisol iso-C9 acid's production and use in the synthesis of various dyes, drugs, perfumes, antiseptics and fungicides, in ore separations, synthetic flavors(1), hydraulic fluids, machining oils, flotation agents, and as a wood preservative(2) may result in its release to the environment through various waste streams(SRC). AEROBIC: Multisol iso-C9 acid reached 43, 53, 64 and 63% of its theoretical BOD after 2, 5, 10, and 30 days, respectively using a domestic sewage inoculum and an Multisol iso-C9 acid concn of 3.0 ppm(1). 100% decreases in initial Multisol iso-C9 acid concns of 0.5 mg/L and 4.3 mg/L were observed after 21 days incubation in aerobic mixed bacterial cultures obtained from trench leachate at low-level radioactive waste disposal sites in Maxey Flats, KY and West Valley, NY, respectively(2). Multisol iso-C9 acid reached 60% of its theoretical oxygen demand after 5 days using a sewage seed(3). After a lag period of 2.2 days, Multisol iso-C9 acid present at a concn of 10,000 ppm, reached 60, 66, and 68% of its theoretical BOD after 5, 10, and 20 days, respectively using a sewage seed(4). Use of an adapted sewage seed reduced the lag period to 1.6 days, after which Multisol iso-C9 acid reached 60, 69, and 70% of its theoretical BOD after 5, 10, and 20 days, respectively(4). In Warburg respirometer tests using an activated sludge seed, Multisol iso-C9 acid, present at a concn of 500 ppm, reached 9.8, 20.4, and 32.8% of its theoretical oxygen demand after 6, 12, and 24 hours incubation, respectively(5). After 24 hours incubation, Multisol iso-C9 acid, present at a concn of 500 ppm, reached 5 and 59% of its theoretical oxygen demand using activated sludge inoculum from two different municipal sources(5). In a Warburg test using an activated sludge inoculum acclimated to phenol, Multisol iso-C9 acid, present at a concn of 500 ppm, reached 20% of its theoretical BOD after 12 hours(6). Two bacterial soil isolants were able to utilize octanoate as a growth substrate(7). A total organic carbon removal ratio of 97% was observed for Multisol iso-C9 acid using a non-acclimated activated sludge and an initial Multisol iso-C9 acid concn of 100 mg total organic carbon/L(8).
m-Xylenediamine
Glutamic acid, monosodium salt; MSG; L-Glutamic Acid Monosodium Salt; Sodium L-Glutamate, Mono; L-(+)sodium glutamate; Glutamate monosodium salt; monosodium-L-glutamate; sodium-L-glutamate; L-Glutamic acid, monosodium salt, monohydrate; Glutammato Monosodico (Italian); Natriumglutaminat (German); Hidrogenoglutamato de sodio (Spanish); Hydrogénoglutamate de sodium (French) CAS NO: 142-47-2 (Anhydrous) 6106-04-3 (Monohydrate)
MYRISTIC ACID
SYNONYMS n-Tetradecoic acid; 1-Tridecanecarboxylic acid; n-Tetradecanoic acid; Crodacid; Hydrofol acid 1495; n-Tetradecan-1-oic acid; CAS NO. 544-63-8
MYRISTIC ACID
Myristic Acid is a fatty acid that occurs naturally in some foods.
Myristic Acid is a fatty acid found in nutmeg, palm oil, coconut oil, butter fat, and spermacetin, the oil from the sperm whale.
Myristic Acid (IUPAC name: tetradecanoic acid) is a common saturated fatty acid with the molecular formula CH3(CH2)12COOH.


CAS Number: 544-63-8
EC Number: 208-875-2
Chemical formula: C14H28O2


Myristic Acid's salts and esters are commonly referred to as myristates or tetradecanoates.
Myristic Acid is named after the binomial name for nutmeg (Myristica fragrans), from which it was first isolated in 1841 by Lyon Playfair.
Myristic acid — also known as tetradecanoic acid — is a saturated fatty acid with 14 carbon atoms that has many industrial applications.
Myristic acid is a minimum 98-percent pure and obtained wholly from vegetable-based (palm oil) sources.


Myristic Acid has a 14 carbon length fatty acid that can be naturally found in nutmeg, palm kernel oil, coconut oil and butter fat.
Myristic Acid, a 14 carbon saturated fatty acid, is a rare molecule in cells and is a substrate of some fatty acid desaturases.
This compound has the ability to acylate proteins by covalently binding to the N-terminal glycine residues, in a process called N-terminal myristoylation.


Myristoylation of substrate proteins by this fatty acid has the potential to activate and mediate many physiological pathways.
Furthermore, saturated fatty acids have been reported to be essential for biological activities of lipopolysaccharides and have demonstrated the ability to induce expression of COX-2 and NFκB (nuclear factor κB) activation.


Myristic Acid can add to the oil-phase of the formula or in phase with surfactants.
Typical use level of Myristic Acid is 0.5-10%.
Myristic Acid is a C14 saturated fatty acid that is attached via an amide bond to the amino group of the N-terminal glycine residue, which aids in the anchorage of MARCKS to the plasma membrane.


Myristic Acid, a saturated fatty acid consisting of 14 carbon atoms, plays a unique role in cellular processes as a substrate for certain fatty acid desaturases.
Commonly found in animal and vegetable fats, myristic acid is integral to various biological functions, including cell membrane formation, signal transduction, and energy metabolism.


Myristic Acid synthesis from other fatty acids is crucial for generating a diverse range of products, such as pharmaceuticals, food additives, and cosmetics.
The scientific applications of myristic acid encompass a broad spectrum of research areas.


Myristic Acid serves as a tool for investigating the impact of fatty acid metabolism on the body and the role of fatty acids in signal transduction and cell membrane formation.
Moreover, myristic acid enables the exploration of how fatty acids influence the structure and function of proteins and enzymes.


Through a process known as N-terminal myristoylation, myristic acid can acylate proteins by covalently binding to N-terminal glycine residues, which activates and mediates numerous physiological pathways.
Furthermore, saturated fatty acids, including myristic acid, have been observed to be vital for the biological activities of lipopolysaccharide.


They can also induce the expression of COX-2 and activate NFκB (nuclear factor κB).
In summary, myristic acid plays an essential role in diverse biological processes and serves as a valuable tool in scientific research to elucidate its effects and implications.


Myristic Acid is a common saturated fatty acid found in nutmeg, palm kernel oil, coconut oil and butter fat.
Myristic Acid belongs to the class of organic compounds known as long-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms.


Myristic acid, also known as tetradecanoic acid or C14:0, belongs to the class of organic compounds known as long-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms.
Myristic acid (its ester is called myristate) is a saturated fatty acid that has 14 carbons; as such, it is a very hydrophobic molecule that is practically insoluble in water.


Myristic Acid exists as an oily white crystalline solid.
Myristic acid is found in all living organisms ranging from bacteria to plants to animals, and is found in most animal and vegetable fats, particularly butterfat, as well as coconut, palm, and nutmeg oils.


Industrially, myristic acid is used to synthesize a variety of flavour compounds and as an ingredient in soaps and cosmetics.
Within eukaryotic cells, myristic acid is also commonly conjugated to a penultimate N-terminal glycine residue in receptor-associated kinases to confer membrane localization of these enzymes (a post-translational modification called myristoylation via the enzyme N-myristoyltransferase).


Myristic acid has a high enough hydrophobicity to allow the myristoylated protein to become incorporated into the fatty acyl core of the phospholipid bilayer of the plasma membrane of eukaryotic cells.
Also, Myristic Acid is known because it accumulates as fat in the body; however, its consumption also impacts positively on cardiovascular health.


Salts of Myristic Acid (Aluminum Dimyristate, Aluminum Isostearates/Myristate, Aluminum Myristate, Aluminum Myristates/Palmitates, Calcium Myristate, Magnesium Myristate, Potassium Myristate, Sodium Myristate, Zinc Myristate) and esters of Myristic Acid (Butyl Myristate, Cetyl Myristate, Decyl Myristate, Ethylhexyl Myristate, Ethyl Myristate, Glyceryl Dimyristate, Glyceryl Isostearate/Myristate, Glyceryl Myristate, Isobutyl Myristate, Isocetyl Myristate, Isodecyl Myristate, Isopropyl Myristate, Isostearyl Myristate, Isotridecyl Myristate, Lauryl Myristate, Methyl Myristate, Myristyl Myristate, Octyldodecyl
Myristate, Oleyl Myristate, Propylene Glycol Myristate, Tetradecyloctadecyl Myristate, Tridecyl Myristate) may also be used in cosmetics and personal care products. Myristic Acid and its salts and esters may be used in eye makeup, soaps and detergents, hair care products, nail care products, shaving products and other skin care products.


Myristic acid is named after the scientific name for nutmeg, Myristica fragrans, from which it was first isolated in 1841 by Lyon Playfair.
Purified Myristic Acid occurs as a hard, white or faintly yellow, glossy crystalline solid, or as a white or yellow-white powder.
Myristic Acid is a fatty acid found in nutmeg, palm oil, coconut oil, butter fat, and spermacetin, the oil from the sperm whale.


Also called tetradecanoic acid, myristic acid is a fractionated saturated fatty acid that occurs naturally in certain fats and oils including nutmeg butter, coconut oil, and palm oil.
Myristic Acid, also known as tetradecanoic acid, is a saturated fatty acid that acts as a lipid anchor in biomembranes.
Myristic acid is obtained from the fractionation of a lauric-type oil.


Myristic acid obtained has a melting point above 55 º C.
Myristic Acid is solid at room temperature, opaque white and with a characteristic odour.
Myristic acid, also known as 14 or tetradecanoate, belongs to the class of organic compounds known as long-chain fatty acids.


These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms.
Myristic acid is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.
Myristic Acid is an oily white crystalline solid.


Myristic Acid is a straight-chain, fourteen-carbon, long-chain saturated fatty acid mostly found in milk fat.
Myristic Acid has a role as a human metabolite, an EC 3.1.1.1 (carboxylesterase) inhibitor, a Daphnia magna metabolite and an algal metabolite.
Myristic Acid is a long-chain fatty acid and a straight-chain saturated fatty acid.


Myristic Acid is a conjugate acid of a tetradecanoate.
Myristic acid is a metabolite found in or produced by Escherichia coli.
Myristic acid is a natural product found in Gladiolus italicus, Staphisagria macrosperma, and other organisms with data available.


Myristic Acid is a saturated long-chain fatty acid with a 14-carbon backbone.
Myristic acid is found naturally in palm oil, coconut oil and butter fat.
Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.


Lauric acid and myristic acid are saturated fatty acids.
Their formal names are dodecanoic acid and tetradecanoic acid, respectively.
Both are white solids that are very slightly soluble in water.


Lauric acid esters (principally triglycerides) are found only in vegetable fats, primarily from coconut milk and oil, laurel oil, and palm kernel oil.
In contrast, myristic acid triglycerides occur in plants and animals, notably in nutmeg butter, coconut oil, and mammalian milk.
This fatty acid, Myristic Acid, is known because it accumulates fat in the body, however, its consumption also impacts positively on cardiovascular health.


This behavior is largely influenced by the balance between saturated fatty acid and simple dietary carbohydrates in the diet.
Myristic acid is directly involved in post-translational protein changes and mechanisms that control important metabolic processes in the human body.
Myristic Acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.



USES and APPLICATIONS of MYRISTIC ACID:
Nutmeg, palm oil and coconut oil contain high levels of myristic acid.
Myristic Acid is widely used as raw material in the production of emulsifiers, anionic & nonionic surfactants, ester & flavors.
Myristic Acid is used for external use only.


Myristic Acid is used all kinds of personal care products including soaps, cleansing creams, lotions, hair conditioners, shaving products.
Myristic Acid has a variety of uses in the beauty industry, including as a: Fragrance Ingredient; Opacifying Agent; Surfactant; Cleansing Agent; and Emulsifier (Source).


One of Myristic Acid's primary properties is as a lubricant, due to its high rate of absorption by the skin.
Myristic Acid's used as a foam building cleansing agent.
Myristic acid is a cleansing agent that also creates foam and, due to its relation to soap, can be drying.


Fractionated fatty acids are mainly used in the manufacture of: Amines, esters, fatty alcohols, peroxides, fragrances, flavors, surface finishing, lubricants, metal soaps, cosmetics, animal feed, chemical, paper, plastics, detergents, resins and coatings.
Ungraded products supplied by TCI America are generally suitable for common industrial uses or for research purposes but typically are not suitable for human consumption or therapeutic use.


Myristic Acid is used to synthesize flavor and as an ingredient in soaps and cosmetics.
Myristic acid is also commonly added to a penultimate nitrogen terminus glycine in receptor-associated kinases to confer the membrane localisation of the enzyme.


This is achieved by the myristic acid having a high enough hydrophobicity to become incorporated into the fatty acyl core of the phospholipid bilayer of the plasma membrane of the eukaryotic cell.
Myristic Acid is a metabolite found in or produced by Saccharomyces cerevisiae.


Myristic Acid is used to synthesize flavor and as an ingredient in soaps and cosmetics.
Myristic acid is used for synthesis.
Myristic acid, a long-chain saturated fatty acid (14:0), is one of the most abundant fatty acids in milk fat (above 10%).



BENEFITS OF MYRISTIC ACID:
Myristic Acid is used primarily as a surfactant, cleansing and thickening agent
Myristic Acid has good emulsifying and opacifying properties
Myristic Acid provides some thickening effects



WHAT DOES MYRISTIC ACID DO IN A FORMULATION?
*Cleansing
*Emulsifying
*Perfuming



ALTERNATIVE PARENTS OF MYRISTIC ACID:
*Straight chain fatty acids
*Monocarboxylic acids and derivatives
*Carboxylic acids
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS OF MYRISTIC ACID:
*Long-chain fatty acid
*Straight chain fatty acid
*Monocarboxylic acid or derivatives
*Carboxylic acid
*Carboxylic acid derivative
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Organooxygen compound
*Carbonyl group
*Aliphatic acyclic compound



CHEMICAL BEHAVIOUR OF MYRISTIC ACID:
Myristic acid acts as a lipid anchor in biomembranes.
Reduction of myristic acid yields myristyl aldehyde and myristyl alcohol.



OCCURRENCE OF MYRISTIC ACID:
Nutmeg butter has 75% trimyristin, the triglyceride of myristic acid and a source from which it can be synthesised.
Besides nutmeg, myristic acid is found in palm kernel oil, coconut oil, butterfat, 8–14% of bovine milk, and 8.6% of breast milk as well as being a minor component of many other animal fats.
Myristic Acid is found in spermaceti, the crystallized fraction of oil from the sperm whale.
Myristic Acid is also found in the rhizomes of the Iris, including Orris root.



WHY IS MYRISTIC ACID USED IN COSMETICS AND PERSONAL CARE PRODUCTS?
The following functions have been reported for Myristic Acid and its salts and esters.
*Anticaking agent – Aluminum Dimyristate, Aluminum Isostearates/Myristates, Aluminum Myristate, Aluminum Myristates/Palmitates, Calcium Myristate, Magnesium Myristate, Zinc Myristate

*Binder – Isopropyl Myristate, Isostearyl Myristate, Tetradecyloctyldecyl Myristate
*Emulsion stabilizer – Aluminum Dimyristate, Aluminum Isostearates/Myristates, Aluminum Myristate, Aluminum Myristates/Palmitates, Calcium Myristate, Tetradecyloctyldecyl Myristate

*Film former – Tetradecyloctyldecyl Myristate
Hair conditioning agent – Ethyl Myristate, Isotridecyl Myristate, Lauryl Myristate, Oleyl Myristate
*Opacifying agent – Myristic Acid, Tetradecyloctyldecyl Myristate

*Slip modifier – Magnesium Myristate, Zinc Myristate
*Skin-Conditioning Agent – Emollient – Butyl Myristate, Ethylhexyl Myristate, Ethyl Myristate, Glyceryl Dimyristate, Glyceryl Isostearate/Myristate, Glyceryl Myristate, Isobutyl Myristate, Isodecyl Myristate, Isopropyl Myristate, Isostearyl Myristate, Methyl Myristate, Propylene Glycol Myristate

*Skin-conditioning agent – occlusive – Cetyl Myristate, Decyl Myristate, Isocetyl Myristate, Isotridecyl Myristate, Lauryl Myristate, Myristyl Myristate, Octyldodecyl Myristate, Oleyl Myristate, Tetradecyloctyldecyl Myristate, Tridecyl Myristate
*Surfactant – cleansing agent – Myristic Acid, Potassium Myristate, Sodium Myristate

*Surfactant – emulsifying agent – Potassium Myristate, Sodium Myristate, Glyceryl Isostearate/Myristate, Glyceryl Myristate, Propylene Glycol Myristate
*Viscosity increasing agent – nonaqueous – Aluminum Dimyristate, Aluminum Isostearates/Myristates, Aluminum Myristate, Aluminum Myristates/Palmitates, Calcium Myristate, Magnesium Myristate, Zinc Myristate



SCIENTIFIC FACTS OF MYRISTIC ACID:
Myristic Acid, also called tetradecanoic acid, occurs naturally in vegetable or animal fats and oils with relatively high levels found in nutmeg, palm oil, coconut oil and butter fat.
The salts of Myristic acid are formed by reaction with base materials such as sodium or potassium hydroxide.
The esters of Myristic Acid are derived from Myristic Acid and an alcohol.
For example, Isopropyl Myristate is derived from Myristic Acid and isopropyl alcohol, and Butyl Myristate is derived from Myristic Acid and butyl alcohol.



FUNCTIONS OF MYRISTIC ACID:
Myristic Acid is a fatty acid found in nutmeg, palm oil, coconut oil, butter fat, and spermacetin, the oil from the sperm whale, according to Wikipedia.
Myristic Acid has a variety of uses in the beauty industry, including as a: Fragrance Ingredient; Opacifying Agent; Surfactant; Cleansing Agent; and Emulsifier (Source).
One of Myristic Acid's primary properties is as a lubricant, due to its high rate of absorption by the skin.



PHYSICAL and CHEMICAL PROPERTIES of MYRISTIC ACID:
Chemical formula: C14H28O2
Molar mass: 228.376 g·mol−1
Appearance: colorless or white solid
Density: 1.03 g/cm3 (−3 °C), 0.99 g/cm3 (24 °C), 0.8622 g/cm3 (54 °C)
Melting point: 54.4 °C (129.9 °F; 327.5 K)
Boiling point: 326.2 °C (619.2 °F; 599.3 K) at 760 mmHg
250 °C (482 °F; 523 K) at 100 mmHg
218.3 °C (424.9 °F; 491.4 K) at 32 mmHg
Solubility in water: 13 mg/L (0 °C)
20 mg/L (20 °C), 24 mg/L (30 °C), 33 mg/L (60 °C)
Solubility: Soluble in alcohol, acetates, C6H6, haloalkanes, phenyls, nitros
Solubility in acetone: 2.75 g/100 g (0 °C)
15.9 g/100 g (20 °C), 42.5 g/100 g (30 °C), 149 g/100 g (40 °C)
Solubility in benzene: 6.95 g/100 g (10 °C)
29.2 g/100 g (20 °C), 87.4 g/100 g (30 °C), 1.29 kg/100 g (50 °C)
Solubility in methanol: 2.8 g/100 g (0 °C)
17.3 g/100 g (20 °C), 75 g/100 g (30 °C), 2.67 kg/100 g (50 °C)

Solubility in ethyl acetate: 3.4 g/100 g (0 °C)
15.3 g/100 g (20 °C), 44.7 g/100 g (30 °C), 1.35 kg/100 g (40 °C)
Solubility in toluene: 0.6 g/100 g (−10 °C)
3.2 g/100 g (0 °C), 30.4 g/100 g (20 °C), 1.35 kg/100 g (50 °C)
log P: 6.1
Vapor pressure: 0.01 kPa (118 °C)
0.27 kPa (160 °C), 1 kPa (186 °C)
Magnetic susceptibility (χ): -176·10−6 cm3/mol
Thermal conductivity: 0.159 W/m·K (70 °C)
0.151 W/m·K (100 °C), 0.138 W/m·K (160 °C)
Refractive index (nD): 1.4723 (70 °C)
Viscosity: 7.2161 cP (60 °C)
3.2173 cP (100 °C), 0.8525 cP (200 °C), 0.3164 cP (300 °C)
Structure
Crystal structure: Monoclinic (−3 °C)
Space group: P21/c
Lattice constant:
a = 31.559 Å, b = 4.9652 Å, c = 9.426 Å
α = 90°, β = 94.432°, γ = 90°

Thermochemistry
Heat capacity (C): 432.01 J/mol·K
Std enthalpy of formation (ΔfH⦵298): −833.5 kJ/mol
Std enthalpy of combustion (ΔcH⦵298): 8675.9 kJ/mol
Molecular Weight: 228.37 g/mol
XLogP3: 5.3
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 12
Exact Mass: 228.208930132 g/mol
Monoisotopic Mass: 228.208930132 g/mol
Topological Polar Surface Area: 37.3Ų
Heavy Atom Count: 16
Formal Charge: 0
Complexity: 155
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

CAS number: 544-63-8
EC number: 208-875-2
Hill Formula: C₁₄H₂₈O₂
Chemical formula: CH₃(CH₂)₁₂COOH
Molar Mass: 228.38 g/mol
HS Code: 2915 90 70
Boiling point: 326 °C (1013 hPa)
Density: 0.8622 g/cm3 (54 °C)
Melting Point:58.5 °C
Vapor pressure: Solubility: 1.07 mg/l
CAS number: 544-63-8
EC number: 208-875-2
Hill Formula: C₁₄H₂₈O₂
Chemical formula: CH₃(CH₂)₁₂COOH
Molar Mass: 228.38 g/mol
HS Code: 2915 90 70
Boiling point: 326 °C (1013 hPa)
Density: 0.8622 g/cm3 (54 °C)
Melting Point: 58.5 °C
Vapor pressure: Solubility: 1.07 mg/l

Physical state: scales
Color: white
Odor: No data available
Melting point/freezing point:
Melting point: 58,5 °C
Initial boiling point and boiling range:
250 °C at 133 hPa, 326 °C at 1.013 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: > 113,00 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: 0,8622 g/cm3 at 54 °C
Relative density: No data available

Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Appearance: white to pale yellow waxy crystalline powder (est)
Assay: 98.00 to 100.00 sum of isomers
Water Content: <0.20%
Food Chemicals Codex Listed: Yes
Melting Point: 53.00 to 56.00 °C. @ 760.00 mm Hg
Boiling Point: 250.00 °C. @ 100.00 mm Hg
Boiling Point: 242.00 to 249.00 °C. @ 760.00 mm Hg
Congealing Point: 48.00 to 55.00 °C.
Saponification Value: 242.00 to 251.00
Unsaponifiable Matter: <1.00%
Vapor Density: >1 ( Air = 1 )
Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 6.110
Soluble in: alcohol, chloroform, ether
water, 1.07 mg/L @ 25 °C (exp)



FIRST AID MEASURES of MYRISTIC ACID:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed
No data available



ACCIDENTAL RELEASE MEASURES of MYRISTIC ACID:
-Environmental precautions:
No special precautionary measures necessary.
-Methods and materials for containment and cleaning up:
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of MYRISTIC ACID:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
none



EXPOSURE CONTROLS/PERSONAL PROTECTION of MYRISTIC ACID:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
No special precautionary measures necessary.



HANDLING and STORAGE of MYRISTIC ACID:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of MYRISTIC ACID:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available
-Incompatible materials:
No data available



SYNONYMS:
Tetradecanoic acid
C14:0 (Lipid numbers)
Tetradecanoic acid
MYRISTIC ACID
544-63-8
n-Tetradecanoic acid
Crodacid
n-Tetradecan-1-oic acid
n-Tetradecoic acid
1-Tridecanecarboxylic acid
Hydrofol acid 1495
Myristinsaeure
Univol U 316S
Emery 655
Myristate
tetradecoic acid
Hystrene 9014
Myristic acid, pure
FEMA No. 2764
Myristic acid (natural)
acide tetradecanoique
n-Myristic acid
NSC 5028
CCRIS 4724
HSDB 5686
Tetradecanoate
Philacid 1400
C14:0
Prifac 2942
CH3-[CH2]12-COOH
CHEBI:28875
AI3-15381
NSC-5028
1-tetradecanecarboxylic acid
EINECS 208-875-2
PHILACID-1400
UNII-0I3V7S25AW
PRIFRAC-2942
BRN 0508624
0I3V7S25AW
Myristic acid [NF]
DTXSID6021666
Edenor C 14
MyristicAcid-13C14
CHEMBL111077
DTXCID501666
MYRISTIC-14-13C ACID
NSC5028
4-02-00-01126 (Beilstein Handbook Reference)
MFCD00002744
FA 14:0
n-tetradecan-1-oate
MYRISTIC ACID (II)
MYRISTIC ACID [II]
MYRISTIC ACID (MART.)
MYRISTIC ACID [MART.]
MYRISTIC ACID (USP-RS)
MYRISTIC ACID [USP-RS]
CH3-(CH2)12-COOH
62217-70-3
32112-52-0
Acid, Myristic
CAS-544-63-8
Acid, Tetradecanoic
myristoate
myristoic acid
n-Tetradecanoate
Tetradecanoicacid
3usx
Myristic acid pure
Myristic Acid Flake
fatty acid 14:0
Hystrene 9514
Myristic Acid 655
TETRADECANSAEURE
1-Tridecanecarboxylate
ACIDO MYNISTICO
MAGNESIUMARSENATE
Myristic acid, 95%
Myristic acid, natural
tridecanecarboxylic acid
Myristic acid (8CI)
Myristic Acid, Reagent
3v2n
3w9k
Myristic acid, puriss.
Univol U 3165
Myristic acid, ?99%
Tetradecanoic acid (9CI)
bmse000737
D08OBF
Epitope ID:176772
MYRISTIC ACID [MI]
SCHEMBL6374
MYRISTIC ACID [FCC]
MYRISTIC ACID [FHFI]
MYRISTIC ACID [HSDB]
MYRISTIC ACID [INCI]
MLS002152942
WLN: QV13
Tetradecanoic (Myristic) acid
GTPL2806
NAA 104
NAA 142
IS_D27-TETRADECANOIC ACID
HMS3039E15
HMS3648O20
Myristic acid, analytical standard
HY-N2041
EINECS 250-924-5
Myristic acid, >=98.0% (GC)
Tetradecanoic acid; (Myristic acid)
Tox21_201852
Tox21_302781
BDBM50147581
LMFA01010014
LS-210
s5617
STL185697
Myristic acid, >=95%, FCC, FG
Myristic acid, Sigma Grade, >=99%
AKOS009156714
CCG-266785
DB08231
DS-3833
NSC 122834
NCGC00091068-01
NCGC00091068-02
NCGC00091068-03
NCGC00256547-01
NCGC00259401-01
AC-34674
BP-27915
1-tetradecanecarboxylate
1-tetradecanecarboxylic acid
1-Tridecanecarboxylate
1-Tridecanecarboxylic acid
12-O-Tetradecanoylphorbol 13-acetate
12-Tetradecanoylphorbol 13-acetate
Acide Myristique
acide tetradecanoique
Crodacid
Isopropyl myristate (NF)
myristate
Myristic acid
Myristinsaeure
myristoate
myristoic acid
n-Tetradecan-1-oate
n-Tetradecan-1-oic acid
n-Tetradecanoate
n-Tetradecanoic acid
n-tetradecoate
n-Tetradecoic acid
Phorbol 12-myristate 13-acetate
Tetradecanoate
Tetradecanoic acid
tetradecoate
tetradecoic acid
14
14:0
14:00
C14
CH3-[CH2]12-COOH
Myristic acid pure
Tetradecanoic (myristic) acid
Acid, tetradecanoic
Acid, myristic
FA(14:0)
SMR001224536
CS-0018531
FT-0602832
FT-0770860
M0476
EN300-78099
C06424
Myristic acid, Vetec(TM) reagent grade, 98%
Q422658
SR-01000854525
MYRISTIC ACID (CONSTITUENT OF SAW PALMETTO)
SR-01000854525-3
W-109088
F8889-5016
Z1954802504
EDAE4876-C383-4AD4-A419-10C0550931DB
MYRISTIC ACID (CONSTITUENT OF SAW PALMETTO) [DSC]
Myristic acid, United States Pharmacopeia (USP) Reference Standard
Tetradecanoic acid
1-Tridecanecarboxylic acid
n-Tetradecanoic acid
Myristic acid, Pharmaceutical Secondary Standard
Tetradecanoic Acid
1-Tetradecanoic Acid
1-Tridecanecarboxylic Acid
Edenor C 14
Edenor C 14/98-100
Emery 655
Hystrene 9014
Kortacid 1499
Lunac MY 98
MY 98
NAA 104
NAA 142
NSC 5028
Neo-Fat 14
Philacid 1400
Prifac 2942
Prifrac 2942
Univol U 316S
n-Tetradecan-1-oic Acid
n-Tetradecanoic Acid
n-Tetradecoic Acid
1-Tetradecanecarboxylic acid
14
14:0
14:00
Acide tetradecanoique
C14
CH3-[CH2]12-COOH
Myristinsaeure ChEBI
N-Tetradecan-1-Oic acid
N-Tetradecanoic acid
N-Tetradecoic acid
Tetradecoic acid
Tetradecanoate
1-Tetradecanecarboxylate
N-Tetradecan-1-Oate
N-Tetradecanoate
N-Tetradecoate
Tetradecoate
Tetradecanoic acid
Myristate
1-Tridecanecarboxylate
1-Tridecanecarboxylic acid
Crodacid
Myristic acid pure
Myristoate
Myristoic acid
Tetradecanoic (myristic) acid
Acid, tetradecanoic
Acid, myristic
FA(14:0)
Myristic acid
n-Tetradecanoic acid
n-Tetradecoic acid
Neo-Fat 14
Univol U 316S
1-Tridecanecarboxylic acid
Crodacid
Emery 655
Hydrofol acid 1495
Hystrene 9014
n-Tetradecan-1-oic acid
Hystrene 9514
Philacid 1400
Prifac 2942
Prifrac 2942
NSC 5028
Tetradecanoic acid (myristic acid)
Acide Myristique
Tetradecanoic (Myristic) acid
Myristic acid (tetradecanoic acid)
Tetradecanoic acid (=Myristic acid)


MYRISTIC ACID (C14)

Myristic acid, also known as C14:0 (indicating it is a fatty acid with 14 carbon atoms and no double bonds), is a saturated fatty acid.
Its chemical formula is CH3(CH2)12COOH.
Myristic acid (C14) is classified as a long-chain fatty acid due to its relatively long hydrocarbon chain.
Myristic acid, with its chemical formula CH3(CH2)12COOH, is a saturated fatty acid known for its 14-carbon hydrocarbon chain.

CAS Number: 544-63-8
EC Number: 208-875-2

Tetradecanoic acid, C14 fatty acid, n-Tetradecanoic acid, Myristinic acid, C14:0 fatty acid, N-Myristic acid, N-Tetradecylic acid, C14:0 FA, 1-Tetradecanoic acid, 14:0 fatty acid, C14:0 acid, C14:0 fatty acid, Myristinsäure (German), Ácido mirístico (Spanish), Acide myristique (French), Miristico acido (Italian), Miristinico acido (Italian), Acido n-tetradecanoico (Italian), Acide n-tétradécanoïque (French), Miristinsyra (Swedish), Miristinowa kwas (Polish), Myristinsav (Danish), Myristinezuur (Dutch), Miristinovaya kislota (Russian), Myristiinihappo (Finnish), Myristinska kiselina (Croatian), Miristiinhape (Estonian), Miristinska kiselina (Bosnian), Myristinska kyselina (Czech), Myristinsyra (Norwegian), Miristine rūgštis (Lithuanian), Myristinskaia kislota (Ukrainian), Miristine hlapicata (Slovenian), Kwas mirystynowy (Polish), Myristinskaia kislota (Belarusian), Myristinevá kyselina (Slovak), Märistihape (Estonian), Märistiinhape (Finnish), Myristic acid, Tetradecylic acid, n-Tetradecanoic acid, Myristinic acid, n-Tetradecylic acid, C14:0 fatty acid, N-Myristic acid, N-Tetradecylic acid, C14:0 FA, 1-Tetradecanoic acid, 14:0 fatty acid, C14:0 acid, C14:0 fatty acid, Ácido mirístico (Spanish), Acide myristique (French), Miristico acido (Italian), Miristinico acido (Italian), Acido n-tetradecanoico (Italian), Acide n-tétradécanoïque (French), Miristinsyra (Swedish), Miristinowa kwas (Polish), Myristinsav (Danish).



APPLICATIONS


Myristic acid (C14) finds application in the soap-making industry, contributing to the hardness and lathering properties of soap formulations.
As a key ingredient in shaving creams and foams, myristic acid enhances the stability and texture of these products.
In cosmetic formulations, myristic acid serves as an emollient, providing a smooth and luxurious feel to creams, lotions, and lipsticks.

Myristic acid (C14) is utilized in the production of facial cleansers, where its cleansing properties help remove impurities from the skin.
Myristic acid (C14) is a common ingredient in haircare products, such as shampoos and conditioners, contributing to their texture and cleansing abilities.
In the food industry, myristic acid is present in certain fats and oils, influencing the texture and flavor of chocolate and other confectionery items.

Myristic acid (C14) is employed in the synthesis of surfactants, which find use in detergents and cleaning products.
Myristic acid (C14) is crucial in the production of nutmeg oil, where it contributes to the distinctive aroma of this spice.

Myristic acid (C14) plays a role in the synthesis of certain pharmaceuticals and fragrances, serving as a precursor for various compounds.
Myristic acid (C14) is used in the formulation of lip balms, providing moisture and a smooth texture to protect lips.

As an essential component in the manufacturing of candles, myristic acid contributes to the solidity and burn characteristics of the wax.
In the dairy industry, myristic acid is found in milk and cheese, influencing the flavor and nutritional composition.
Myristic acid is applied in the production of margarine, contributing to the texture and spreadability of this butter substitute.

Myristic acid (C14) is a key ingredient in the formulation of certain antiperspirants and deodorants, aiding in product stability and texture.
Myristic acid (C14)'s inclusion in massage oils enhances their glide and moisturizing properties during body treatments.
In the synthesis of flavor compounds, myristic acid contributes to the overall taste profile of certain food and beverage products.

Myristic acid (C14) is employed in the production of candles, contributing to the hardness and burn characteristics of the wax.
Myristic acid (C14)'s compatibility with other fatty acids makes it a versatile component in the creation of cosmetic and personal care products.
In the pharmaceutical industry, myristic acid is used in the formulation of certain medications and topical treatments.

Myristic acid (C14) is found in certain dietary supplements, where it may contribute to overall fatty acid intake.
Myristic acid (C14) is present in some insect repellents, contributing to the formulation's stability and efficacy.
Myristic acid (C14) is used in the creation of specialty soaps, contributing to their unique textures and properties.

In the formulation of lubricants, myristic acid serves as a component to enhance the overall performance of the product.
Myristic acid (C14) is applied in the production of certain industrial coatings, where its properties contribute to film formation and stability.
Myristic acid (C14) continues to find applications in various industrial processes, showcasing its versatility in diverse fields.

Myristic acid (C14) is utilized in the production of certain pharmaceutical capsules and tablets, aiding in their overall stability.
In the textile industry, myristic acid is applied in fabric softeners, contributing to the soft and smooth feel of textiles.

Myristic acid (C14) is used in the formulation of certain industrial lubricants, enhancing their lubricating properties.
Myristic acid (C14) is employed in the creation of specialty candles, where it influences the burning characteristics and scent.
In the paint and coating industry, myristic acid may be used to modify the rheological properties of certain formulations.

Myristic acid (C14) is a component in the creation of certain biofuels, contributing to the overall composition and stability of the fuel.
Myristic acid (C14) is found in certain skin creams and ointments, contributing to their texture and moisturizing effects.

Myristic acid (C14) is utilized in the manufacturing of certain plasticizers, contributing to the flexibility of plastics.
Myristic acid (C14) is present in the formulation of some perfumes and colognes, contributing to their overall fragrance profile.

Myristic acid (C14) is used in the synthesis of certain flavors and fragrances, imparting unique and desirable notes to the final product.
Myristic acid (C14) is employed in the production of leather treatments, contributing to the softening and conditioning of leather goods.
In the creation of certain adhesives, myristic acid may be used to enhance the adhesive properties and durability.

Myristic acid (C14) is found in some bio-based polymers, influencing their mechanical and thermal properties.
Myristic acid (C14) is applied in the synthesis of certain corrosion inhibitors, contributing to the protection of metals from corrosion.
Myristic acid (C14) is used in the formulation of certain insecticides, contributing to the effectiveness of the pest control product.
In the creation of specialty waxes, myristic acid influences the hardness and melting characteristics of the wax.

Myristic acid (C14) is applied in the production of certain candles with therapeutic properties, contributing to aromatherapy practices.
Myristic acid (C14) is utilized in the creation of certain industrial cutting fluids, contributing to the lubrication and cooling of cutting tools.

Myristic acid (C14) may be present in the formulation of certain bio-based plastics, contributing to their biodegradability.
Myristic acid (C14) is applied in the production of certain bio-based fuels, contributing to the overall composition and energy content.

Myristic acid (C14) is used in the creation of some biodegradable detergents, contributing to their cleaning efficiency.
In the textile industry, myristic acid is applied in fabric dyeing processes to enhance the absorption of certain dyes.
Myristic acid (C14) is utilized in the production of certain bio-based polymers, contributing to their overall sustainability.

Myristic acid (C14) is found in certain natural cosmetics, where it may contribute to the formulation's texture and skin-conditioning properties.
Myristic acid (C14) continues to find applications in research and development, showcasing its potential in emerging fields and technologies.

Myristic acid (C14) is employed in the formulation of certain veterinary pharmaceuticals, contributing to their stability and effectiveness.
In the production of specialty candles, myristic acid enhances the fragrance dispersion and burning characteristics of the wax.

Myristic acid (C14) is used in the creation of certain bio-based plastics, contributing to their structural integrity and biodegradability.
Myristic acid finds application in the synthesis of certain antioxidants, contributing to the preservation of certain products.

In the manufacturing of certain bio-based polymers, myristic acid influences their mechanical properties and biocompatibility.
Myristic acid (C14) is applied in the production of some specialty inks, contributing to the stability and consistency of the ink.

Myristic acid (C14) is found in the formulation of some biodegradable cleaning agents, contributing to their eco-friendly properties.
In the formulation of certain haircare products, myristic acid contributes to the conditioning and detangling effects on hair.
Myristic acid (C14) is utilized in the production of certain bio-based lubricants, contributing to their lubricating and anti-friction properties.

Myristic acid (C14) may be employed in the synthesis of certain bio-based polymers used in medical implants.
In the manufacturing of certain adhesives, myristic acid contributes to the adhesive strength and durability of the final product.

Myristic acid (C14) is applied in the production of some bio-based plasticizers, enhancing the flexibility of certain plastic materials.
Myristic acid (C14) is used in the synthesis of certain bio-based solvents, contributing to their environmental friendliness.
In the creation of certain bio-based coatings, myristic acid may influence the durability and protective properties of the coating.

Myristic acid (C14) is applied in the formulation of some bio-based detergents, contributing to their cleaning efficiency.
Myristic acid (C14) is found in some bio-based paints, where it may contribute to the viscosity and stability of the paint.
Myristic acid (C14) may be present in the formulation of certain bio-based surfactants, contributing to their emulsifying properties.

In the creation of certain bio-based fuels, myristic acid may contribute to the overall energy content of the fuel.
Myristic acid (C14) is used in the synthesis of certain bio-based polyols, which are utilized in the production of polyurethane foams.

Myristic acid (C14) is employed in the creation of some bio-based emollients, contributing to the moisturizing properties of skincare products.
Myristic acid (C14) is utilized in the formulation of certain bio-based textile softeners, contributing to the softness of fabrics.

In the manufacturing of certain bio-based adjuvants, myristic acid may contribute to the efficacy of agricultural pesticides.
Myristic acid (C14) is applied in the synthesis of certain bio-based plastic films, used in packaging materials.

Myristic acid (C14) is found in the formulation of certain bio-based hydraulic fluids, contributing to their lubricating properties.
Myristic acid (C14) may be present in the formulation of certain bio-based cosmetic preservatives, contributing to product stability.



DESCRIPTION


Myristic acid, also known as C14:0 (indicating it is a fatty acid with 14 carbon atoms and no double bonds), is a saturated fatty acid.
Its chemical formula is CH3(CH2)12COOH.
Myristic acid (C14) is classified as a long-chain fatty acid due to its relatively long hydrocarbon chain.
Myristic acid, with its chemical formula CH3(CH2)12COOH, is a saturated fatty acid known for its 14-carbon hydrocarbon chain.

Myristic acid (C14) is a solid at room temperature, characterized by a white, crystalline appearance.
Displaying a faint odor, myristic acid contributes to the distinctive fragrance found in natural sources such as nutmeg.

Myristic acid (C14) is a key component in various fats and oils, including coconut oil and palm kernel oil, adding to their nutritional composition.
Myristic acid (C14)'s melting point, around 54–55°C, makes it solidify at typical room temperatures.

Myristic acid (C14) is crucial in soap production, where it lends hardness and cleansing properties to the final product.
In cosmetic formulations, myristic acid contributes to a smooth texture, enhancing the spreadability of creams and lotions.

Found in significant quantities in dairy fats, myristic acid plays a role in the composition of certain cheeses and milk products.
Its presence in natural sources contributes to the rich and creamy texture of certain foods, such as chocolate.

Myristic acid (C14) is often employed as a precursor in the synthesis of various chemicals used in the pharmaceutical and fragrance industries.
With its 14-carbon structure, myristic acid is considered a long-chain fatty acid, influencing its physiological effects in the body.
Myristic acid (C14) is an essential component of cell membranes, contributing to their structural integrity and fluidity.

Myristic acid (C14) is part of the intricate balance of fatty acids in the human body, impacting metabolic processes and energy storage.
In nutmeg, myristic acid not only adds to the spice's aroma but also contributes to its flavor profile.

Dietary sources of myristic acid include certain oils, meats, and dairy products, where it is present in varying concentrations.
Its chemical structure and properties make myristic acid suitable for use in the synthesis of surfactants and emulsifiers.

When consumed in moderation, myristic acid can be part of a balanced diet, providing a source of energy for the body.
Due to its role in soap formulations, myristic acid has been utilized for centuries in traditional soap-making processes.

The incorporation of myristic acid in skincare products helps achieve a luxurious feel, contributing to their sensory appeal.
As a saturated fatty acid, myristic acid lacks double bonds in its hydrocarbon chain, impacting its chemical stability.

Myristic acid (C14)'s compatibility with other fatty acids and oils makes it a versatile ingredient in the formulation of various products.
In the human body, myristic acid is involved in the synthesis of certain hormones, impacting physiological functions.
The fatty acid's presence in natural oils contributes to their overall stability and resistance to rancidity.

Myristic acid (C14) is named after the nutmeg plant, Myristica fragrans, where it was first identified and isolated.
Recognized for its role in both industrial and biological processes, myristic acid continues to be a valuable component in diverse applications.



PROPERTIES


Chemical Properties:

Chemical Formula: CH3(CH2)12COOH
Molecular Formula: C14H28O2
Molecular Weight: Approximately 228.37 g/mol
IUPAC Name: Tetradecanoic acid
Common Name: Myristic acid


Physical Properties:

Physical State: Solid at room temperature
Appearance: White, crystalline
Odor: Faint odor
Melting Point: Around 54–55°C (129–131°F)
Boiling Point: Decomposes before boiling
Density: Varies, depending on the form; approximately 0.862 g/cm³ at 25°C
Solubility in Water: Insoluble
Solubility in Other Solvents: Soluble in organic solvents such as ethanol and ether
Partition Coefficient (Log P): Estimated to be around 6.35


Chemical Properties:

Acidity (pKa): Approximately 4.88



FIRST AID


Inhalation:

Move to Fresh Air:
If myristic acid is inhaled and respiratory irritation occurs, immediately move the affected person to an area with fresh air.

Seek Medical Attention:
If symptoms persist or worsen, seek immediate medical attention. Provide information about the exposure.


Skin Contact:

Remove Contaminated Clothing:
If myristic acid comes into contact with the skin, remove contaminated clothing immediately.

Wash Skin Thoroughly:
Wash the affected skin area with plenty of soap and water.
Use a mild soap to avoid skin irritation.

Seek Medical Attention:
If irritation, redness, or other adverse reactions occur, seek medical attention.


Eye Contact:

Flush Eyes:
If myristic acid comes into contact with the eyes, immediately flush the eyes with gently flowing lukewarm water for at least 15 minutes.

Remove Contact Lenses:
If easily removable, remove contact lenses during the flushing process.

Seek Medical Attention:
Seek immediate medical attention if irritation, redness, or pain persists after flushing.


Ingestion:

Do Not Induce Vomiting:
If myristic acid is ingested, do not induce vomiting unless directed to do so by medical professionals.

Rinse Mouth:
Rinse the mouth with water if the person is conscious and able to swallow.

Seek Medical Attention:
Seek immediate medical attention.
Provide information about the ingested substance.


General First Aid Tips:

Personal Protective Equipment (PPE):
Always wear appropriate personal protective equipment, such as gloves and safety goggles, when handling myristic acid.

Emergency Contacts:
Ensure that emergency contact numbers for medical professionals and poison control are readily available.

Medical Evaluation:
Even if symptoms seem minor, seek medical evaluation after any exposure to myristic acid to rule out potential long-term effects.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including gloves, safety goggles, and a lab coat or protective clothing, to minimize skin contact and eye exposure.
Use respiratory protection if handling myristic acid in conditions where airborne exposure is possible.

Ventilation:
Work in a well-ventilated area or use local exhaust ventilation to control airborne concentrations of myristic acid.
Avoid inhaling vapors or dust.
Use engineering controls to minimize exposure.

Avoid Contact:
Avoid skin contact and eye exposure.
In case of contact, follow the first aid measures mentioned earlier.

Safe Handling Procedures:
Follow standard laboratory procedures for chemical handling.
Use tools such as spatulas or pipettes to handle myristic acid rather than bare hands.

Spill Response:
In case of a spill, follow appropriate spill response procedures.
Use absorbent materials to contain and clean up small spills.
For larger spills, consult with hazardous materials response personnel.

Avoid Incompatible Materials:
Keep myristic acid away from incompatible materials, such as strong oxidizing agents.


Storage:

Container:
Store myristic acid in well-sealed containers made of compatible materials, such as high-density polyethylene (HDPE) or glass.
Ensure containers are labeled with the appropriate hazard information.

Temperature:
Store myristic acid in a cool, dry place. Keep it away from direct sunlight and heat sources.
Maintain storage temperatures according to the chemical's specifications.

Ventilation:
Ensure storage areas are well-ventilated to prevent the accumulation of vapors.

Separation from Incompatibles:
Store myristic acid away from incompatible substances, such as strong acids, bases, and oxidizing agents.

Handling Precautions:
Implement measures to prevent accidental spills and leakage during storage.

Fire Prevention:
Keep myristic acid away from ignition sources.
It is not highly flammable, but precautions should be taken to prevent fires.

Storage Segregation:
Segregate myristic acid from incompatible chemicals to prevent potential reactions.

Access Control:
Limit access to storage areas to authorized personnel only.
Post appropriate warning signs and labels.

Emergency Equipment:
Ensure the availability of emergency equipment, such as eyewash stations and fire extinguishers, near storage areas.

Regular Inspection:
Regularly inspect storage conditions, including containers and surrounding areas, to identify and address any issues promptly.
MYRISTIC ACID (EDENOR C1499)
Tetradecyl alcohol; 1-tetradecanol; Alcohol C-14; n-Tetradecyl alcohol; Tetradecan-1-ol; Myristic alcohol; Tétradecanol (French); cas no: 112-72-1
MYRISTIC ACID ISOPROPYL ESTER
Myristic acid isopropyl ester is odorless when pure.
Myristic acid isopropyl ester may be synthesized by conventional esterification of isopropanol with myristic acid.
Myristic acid isopropyl ester is a fatty acid ester.

CAS: 110-27-0
MF: C17H34O2
MW: 270.45
EINECS: 203-751-4

Myristic acid isopropyl ester is an ester of isopropyl alcohol myristic acid.
Myristic acid isopropyl ester is mainly used as a solubilizer, emulsifier and emollient in cosmetic and topical medicines.
Myristic acid isopropyl ester also finds applications as a flavoring agent in the food industry.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Myristic acid isopropyl ester Chemical Properties
Melting point: ~3 °C (lit.)
Boiling point: 193 °C/20 mmHg (lit.)
Density: 0.85 g/mL at 25 °C (lit.)
Vapor pressure: Refractive index: n20/D 1.434(lit.)
FEMA: 3556 | ISOPROPYL MYRISTATE
Fp: >230 °F
Storage temp.: 2-8°C
Solubility: <0.05mg/l
Form: Liquid
Specific Gravity: 0.855 (20/4℃)
Color: Clear
Odor: odorless
Water Solubility: Miscible with alcohol. Immiscible with water and glycerol.
Merck: 14,5215
JECFA Number: 311
BRN: 1781127
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey: AXISYYRBXTVTFY-UHFFFAOYSA-N
LogP: 7.71
CAS DataBase Reference: 110-27-0(CAS DataBase Reference)
NIST Chemistry Reference: Myristic acid isopropyl ester(110-27-0)
EPA Substance Registry System: Myristic acid isopropyl ester (110-27-0)

Myristic acid isopropyl ester is a colorless and odorless liquid with a faint odor, and miscible with vegetable oil.
Myristic acid isopropyl ester is not easy to be either hydrolyzed or become rancid.
The refractive index nD20 is 1.435~1.438, and the relative density (20°C) is 0.85~0.86.
Myristic acid isopropyl ester is used in many applications, including pharma, food and personal care product manufacturing.
Myristic acid isopropyl ester is virtually odorless, very slightly fatty, but not rancid
Myristic acid isopropyl ester is a clear, colorless, practically odorless liquid of low viscosity that congeals at about 5°C.
Myristic acid isopropyl ester consists of esters of propan-2-ol and saturated high molecular weight fatty acids, principally myristic acid.

Content Analysis
Weight 1.5 g sample.
Then Myristic acid isopropyl ester is determined by the method ester assay (OT-18).
The equivalent factor (e) in the calculation is 135.2.
Or Myristic acid isopropyl ester is determined by a non-polar column method of gas chromatography.

Uses
Myristic acid isopropyl ester is a fatty acid ester which is used as solvent in water-in-oil emulsion, oils and fatty based ointments.
The use of IPM is recommended in the Sterility Test chapter of the European, Japanese and United States Pharmacopoeia as diluent for oils and oily solutions, as well as for ointments and creams.
Indeed, Myristic acid isopropyl ester's solvent properties improve the filterability of these samples.
Myristic acid isopropyl ester is known as a penetration enhancer for topical preparations.
Myristic acid isopropyl ester is a waterclear, low viscous oily liquid with a very good spreading capacity on the skin.
Myristic acid isopropyl ester is mainly used in cosmetics as an oilcomponent for emulsions, bath oils and as a solvent for active substances.

Myristic acid isopropyl ester is an emollient in cosmetic and pharmaceutical bases.
In cosmetic and topical medicinal Preparations where good absorption through the skin is desired.
A jellied isopropyl myristate was marketed as Estergel.
Myristic acid isopropyl ester is an emollient, moisturizer, binder, and skin softener that also assists in product penetration.
An ester of myristic acid, Myristic acid isopropyl ester is naturally occurring in coconut oil and nutmeg.
Although Myristic acid isopropyl ester is generally considered comedogenic, some ingredient manufacturers clearly specify non-comedogenicity on their data sheets.

Pharmaceutical Applications
Myristic acid isopropyl ester is a nongreasy emollient that is absorbed readily by the skin.
Myristic acid isopropyl ester is used as a component of semisolid bases and as a solvent for many substances applied topically.
Applications in topical pharmaceutical and cosmetic formulations include bath oils; make-up; hair and nail care products; creams; lotions; lip products; shaving products; skin lubricants; deodorants; otic suspensions; and vaginal creams.
For example, Myristic acid isopropyl ester is a self-emulsifying component of a proposed cold cream formula, which is suitable for use as a vehicle for drugs or dermatological actives; Myristic acid isopropyl ester is also used cosmetically in stable mixtures of water and glycerol.

Myristic acid isopropyl ester is used as a penetration enhancer for transdermal formulations, and has been used in conjunction with therapeutic ultrasound and iontophoresis.
Myristic acid isopropyl ester has been used in a water-oil gel prolonged-release emulsion and in various microemulsions.
Such microemulsions may increase bioavailability in topical and transdermal applications.
Myristic acid isopropyl ester has also been used in microspheres, and significantly increased the release of drug from etoposide-loaded microspheres.
Myristic acid isopropyl ester is used in soft adhesives for pressuresensitive adhesive tapes.

Pharmacology
Myristic acid isopropyl ester is used in pharmaceutical preparations because it improves solubility and increases absorption through the skin.
External uses include a non-irritating iodine preparation for disinfecting the skin and aerosol bactericidal preparations for feminine hygiene use without irritation of the skin and mucous membranes.
Preparations for internal use include oral steroid formulations and anaesthetic injection solutions.
Veterinary medications containing Myristic acid isopropyl ester include oral or parenteral compositions for lungworm infections and a spray formulation for bovine udders to treat mastitis, combat infection and improve the general skin condition.

Myristic acid isopropyl ester has been found to be an effective repository vehicle for im injection of penicillin in rabbits and for sc administration of oestrogens in ovariectomized rats.
In assays on human forearms, vasoconstrictor activity of ointment preparations containing 0025% betamethasone 17-benzoate in white soft paraffin was increased by the presence of isopropyl myristate.
Donovan, Ohmart & Stoklosa (1954) noted that the good solvent properties of Myristic acid isopropyl ester might increase the therapeutic activity of formulations by the apparent alteration in particle size of the active ingredients, so that further evaluation and clinical study would be necessary before its use in extemporaneous compounding could be recommended.
Studies in which the antifungal activity of paraben esters solubilized by surfactants was decreased by Myristic acid isopropyl ester indicate that the effectiveness of medicinal substances may be influenced by the presence of surfactants and oily ingredients such as isopropyl myristate.

Production Method
Myristic acid isopropyl ester is a product of esterification of myristic acid derived from re-steamed coconut coil with isopropyl alcohol.
(1) 200 kg myristic acid and 450 kg isopropyl alcohol were added into the reaction vessel in turn.
After mixing, 360 kg sulfuric acid (98%) was added.
The reaction mixture was heated to reflux for 10 hours.
Isopropyl alcohol was then recovered, washed with ice water, and neutralized with Na2CO3 aqueous solution (10%).
Under normal pressure, isopropyl alcohol and water were distilled.
While under reduced pressure, isopropyl myristate was distilled (185°C/1.0kPa~195°C/2.7kPa).

(2) 90 kg isopropyl alcohol was added into the reaction vessel and then sulfuric acid as catalyst, with 5% of the total amount, was added.
During mixing, 228 kg myristic acid was added slowly.
The mixture was heated to reflux and water was continuously separated.
Until no water was separated, the reaction temperature was reduced and probe was obtained to measure the acid value.
When the acid value reached 1.5 mg KOH/g, the reaction was completed.
Alkali was then added for neutralization.
After the removal of water under reduced pressure, the pressure was further reduced for dealcoholization until the acid value was 0.05~1.0 mg KOH/g.
The final product is then isopropyl myristate.

Myristic acid isopropyl ester may be prepared either by the esterification of myristic acid with propan-2-ol or by the reaction of myristoyl chloride and propan-2-ol with the aid of a suitable dehydrochlorinating agent.
A high-purity material is also commercially available, produced by enzymatic esterification at low temperature.

Biochem/physiol Actions
Myristic acid isopropyl ester is used to change the physicochemical characteristics of microsheres such as poly(lactic-co-glycolic acid) (PLGA) microspheres.
Myristic acid isopropyl ester is used as a oil phase component in the formulaton of microemulsion systems.

Synonyms
ISOPROPYL MYRISTATE
110-27-0
Isopropyl tetradecanoate
Estergel
Isomyst
Bisomel
Promyr
Tetradecanoic acid, 1-methylethyl ester
Deltyl Extra
Kesscomir
Tegester
Sinnoester MIP
Crodamol IPM
Plymoutm IPM
Starfol IPM
Unimate IPM
Kessco IPM
Stepan D-50
Emcol-IM
Wickenol 101
Emerest 2314
propan-2-yl tetradecanoate
1-Methylethyl tetradecanoate
Deltylextra
Myristic acid isopropyl ester
JA-FA IPM
Crodamol I.P.M.
Kessco isopropyl myristate
FEMA No. 3556
Tetradecanoic acid, isopropyl
Myristic acid, isopropyl ester
Tetradecanoic acid, isopropyl ester
Caswell No. 511E
HSDB 626
NSC 406280
Isopropyl myristate [USAN]
1-Tridecanecarboxylic acid, isopropyl ester
UNII-0RE8K4LNJS
0RE8K4LNJS
EINECS 203-751-4
Estergel (TN)
EPA Pesticide Chemical Code 000207
NSC-406280
BRN 1781127
methylethyl tetradecanoate
iso-Propyl N-tetradecanoate
DTXSID0026838
CHEBI:90027
EC 203-751-4
Tetradecanoic acid methyethyl ester
1405-98-7
NCGC00164071-01
WE(2:0(1Me)/14:0)
MYRISTIC ACID, ISOPROPYL ALCOHOL ESTER
Isopropyl myristate, 98%
TETRADECONOIC ACID, 1-METHYLETHYL ESTER
DTXCID306838
ISOPROPYL MYRISTATE (II)
ISOPROPYL MYRISTATE [II]
ISOPROPYL MYRISTATE (MART.)
ISOPROPYL MYRISTATE [MART.]
ISOPROPYL MYRISTATE (USP-RS)
ISOPROPYL MYRISTATE [USP-RS]
CAS-110-27-0
ISOPROPYL MYRISTATE (EP MONOGRAPH)
ISOPROPYL MYRISTATE [EP MONOGRAPH]
MFCD00008982
tetradecanoic acid 1-methylethyl ester
Deltyextra
Tegosoft M
MYRISTIC ACID ISOPROPYL ESTER
MYRISTIC ACID ISOPROPYL ESTER = IPM = ISOPROPYL TETRADECANOATE


CAS Number: 110-27-0
EC Number: 203-751-4
MDL number: MFCD00008982
Linear Formula: CH3(CH2)12COOCH(CH3)2 / C17H34O2


Myristic acid isopropyl ester (IPM) is the ester of isopropyl alcohol and myristic acid.
Hydrolysis of the ester from Myristic acid isopropyl ester can liberate the acid and the alcohol.
Myristic acid isopropyl ester is theorized to be responsible for decreasing of the pH value of formulations.
Myristic acid isopropyl ester is a natural product found in Siraitia grosvenorii, Mangifera indica, and other organisms with data available.


Myristic acid isopropyl ester is a fatty acid ester.
Myristic acid isopropyl ester was the preferable solvent for theophylline partitioning into the stratum corneum.
Myristic acid isopropyl ester is an ester of isopropanol and myristic acid.
Myristic acid isopropyl ester is also referred to as tetradecanoic acid.


Myristic acid isopropyl ester is manufactured from vegetable oil sources to a minimum 98-percent purity.
Myristic acid isopropyl ester can be used in some of the most demanding industrial applications and has been manufactured to the highest standards of eco-friendly management.


Myristic acid isopropyl ester is a component of emulsion gel for topical delivery of pharmaceuticals, such as dexibuprofen or estrogen.
Myristic acid isopropyl ester is composed of of isopropyl alcohol and myristic acid, a common, naturally occurring fatty acid.
Myristic acid isopropyl ester is fatty acid ester of isopropyl alcohol and myristic acid.


Myristic acid isopropyl ester is the ester of isopropyl alcohol and myristic acid.
Myristic acid isopropyl ester mainly works as an emollient in cosmetics and personal care products.
Myristic acid isopropyl ester has an oily base with low viscosity and adapts well to the skin.
Myristic acid isopropyl ester is a texture enhancer and emollient as used in cosmetics.


Myristic acid isopropyl ester can also help to enhance the absorption of ingredients in a cosmetic formula.
Myristic acid isopropyl ester is commercially produced by distillation, before which the esterification of myristic acid and isopropanol is carried out, and the resulting alkali is refined to neutralize the catalyst, and the product is then distilled to obtain isopropyl myristate.


Myristic acid isopropyl ester is an ester of isopropyl alcohol and myristic acid (vegetable-derived).
Myristic acid isopropyl ester is a Low viscosity fluid non-greasy emollient, tolerates a wide pH range, compatible with most surfactants.
Thanks to its low viscosity and density, Myristic acid isopropyl ester has a high spreadability.


Myristic acid isopropyl ester's Specific gravity is 0.85 (at 20°C).
Myristic acid isopropyl ester is soluble in castor oil, cottonseed oil, acetone, benzene, ether, chloroform, ethyl acetate, ethanol, toluene, and mineral oil.
Myristic acid isopropyl ester dissolves many waxes, cholesterol, lanolin.


Myristic acid isopropyl ester is a non-branched saturated fatty acid ester obtained from isopropanol and myristic acid, from palm oil.
Myristic acid isopropyl ester is clear liquid with a melting point of -3 ºC.
Myristic acid isopropyl ester is produced from myristic acid, derived from vegetable oil & isopropanol (or isopropyl alcohol).
Myristic acid isopropyl ester is the ester of myristic acid and isopropanol.


Myristic acid isopropyl ester (sometimes abbreviated as IPM) is a colorless and oily liquid.
Myristic acid isopropyl ester is a clear and colourless oil of medium polarity.
Myristic acid isopropyl ester is the ester of isopropanol and myristic acid.
Myristic acid isopropyl ester is ester of isopropyl alcohol and myristic acid (vegetable-derived).


Myristic acid isopropyl ester has low viscosity fluid non-greasy emollient, tolerates wide pH range, compatible with most surfactants. Thanks to its low viscosity and density, Myristic acid isopropyl ester has a high spreadability.
Myristic acid isopropyl ester's specific gravity 0.85 is (at 20°C).


Myristic acid isopropyl ester, also commonly known as IPM is a clear, light yellow liquid which oily in appearance and vitually odourless.
Myristic acid isopropyl ester is soluble in most solvents but considered insoluble in water.
Myristic acid isopropyl ester is manufactured by the esterification of isopropyl alcohol with myristic acid.



USES and APPLICATIONS of MYRISTIC ACID ISOPROPYL ESTER:
Myristic acid isopropyl ester is a polar emollient and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired.
Myristic acid isopropyl ester is also used as a treatment for head lice.
Myristic acid isopropyl ester is also in flea and tick killing products for pets.


Myristic acid isopropyl ester is used to remove bacteria from the oral cavity as the non-aqueous component of the two-phase mouthwash product "Dentyl pH".
Myristic acid isopropyl ester is also used as a solvent in perfume materials, and in the removal process of prosthetic make-up.
Myristic acid isopropyl ester has been largely studied and impulsed as a skin penetration enhancer.


Myristic acid isopropyl ester is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption.
At the moment the primary usage for which Myristic acid isopropyl ester is formally indicated is as the active ingredient in a non-prescription pediculicide rinse.


Myristic acid isopropyl ester is a colourless liquid with a faint odor, it is used in many applications, including pharma, food and personal care product manufacturing.
Myristic acid isopropyl ester is notable for promoting the absorption of medicine and other products through the skin.
Myristic acid isopropyl ester is commonly found in creams, lotions and topical medicines.


Myristic acid isopropyl ester is also used as a thickening agent, emollient and moisturizer, as well as a solvent, binder and diluent in perfumes and food flavorings.
Myristic acid isopropyl ester is used in personal care products to enhance their moisturising and skin conditioning properties.
Clean organoleptic quality make Myristic acid isopropyl ester suitable for use as solvent for fragrance.


Myristic acid isopropyl ester is one of the important additives for high-grade cosmetics.
Myristic acid isopropyl ester can be used as emulsifier and moistening agent for cosmetics; dosage is 3~8%.
Myristic acid isopropyl ester is used as emollient and emulsifier in cosmetics and topical medicines, parenteral solvent (intravenous solutions), and reagent in tests for sterility.


Myristic acid isopropyl ester is a Superior emollient for non-greasy bath, body and baby oils.
Myristic acid isopropyl ester is a Lubricant and compression aid for pressed powders.
Myristic acid isopropyl ester is light & non-tacky emollient for creams and lotions.
Myristic acid isopropyl ester is readily adsorbed by the skin.


When used at high concentrations Myristic acid isopropyl ester gently lifts makeup and surface dirt.
Myristic acid isopropyl ester gives gloss and shine to hair.
Myristic acid isopropyl ester is resistant to oxidation (does not become rancid).
Myristic acid isopropyl ester is widely used as diluent for fragrance oils.


Myristic acid isopropyl ester is practically insoluble in glycerol and propylene glycol iso-Propyl myristate, 99% Cas 110-27-0 - used in cosmetic and topical medicinal preparations where good absorption through the skin is desired.
Myristic acid isopropyl ester is an emollient used in cosmetic and pharmaceutical bases.
Further research may identify additional product or industrial usages of Myristic acid isopropyl ester.


Cosmetic formulations of Myristic acid isopropyl ester: binding, fragrance, perfuming, emollient.
Industrial uses of Myristic acid isopropyl ester: washing and cleaning products, lubricants and greases, textile treatment products and dyes, polymers, adhesives, sealants, polishes and waxes.
Myristic acid isopropyl ester is widely used in cosmetics and pharmaceuticals (where it is emulsified with water to improve absorption of the product into the skin).


Myristic acid isopropyl ester is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption.
Myristic acid isopropyl ester has been largely studied and impulsed as a skin penetration enhancer.
Myristic acid isopropyl ester is used as Versatile emollient and lubricant.


Myristic acid isopropyl ester is used in the formulation of pre-shaves & aftershaves, shampoos, bath oils, aerosol antiperspirants, and deodorants.
Uses of Myristic acid isopropyl ester: Topical Medicinal Preparations, Emollient, Moisturizer, Thickening Agent, Solvent, Binder, Diluent.


Myristic acid isopropyl ester can be added to formulas as is, add to oil phase.
Myristic acid isopropyl ester is used Creams, lotions, hand creams, shampoo, shower gels, makeup removers, powders and foundations.
Myristic acid isopropyl ester is used in cosmetics and perfumery as it increases the absorption of perfumes etc on the skin.


-Cosmetic Uses of Myristic acid isopropyl ester:
*binding agents
*perfuming agents
*skin conditioning
*skin conditioning - emollient
*solvents


-Pharmacodynamics use of Myristic acid isopropyl ester:
Myristic acid isopropyl ester is an emollient vehicle that is effective at enhancing the penetration of other medical agents that may be incorporated into the vehicle as active agents.


-Skin care:
Myristic acid isopropyl ester works as an emollient, thickener, and a lubricant in beauty products.
Myristic acid isopropyl ester locks in the hydration, and enhances the penetration of other ingredients in the formulation.
Myristic acid isopropyl ester is an effective agent for solubilizing lanolin.
Therefore, isopropyl myristate is used as a solubilizing, spreading, and penetrating agent in anhydrous skin lubricating lotions with high lanolin content.
Myristic acid isopropyl ester leaves the skin soft and smooth without an oily surface film.
Myristic acid isopropyl ester can even reduce the heavy, greasy feel in products with high oil content.
It's also fast-spreading meaning that Myristic acid isopropyl ester gives the formula a good, nice slip


-Hair care:
Myristic acid isopropyl ester works as a hydrating agent, emollient, and enhancer.
Myristic acid isopropyl ester hydrates the hair and the scalp and enhances the penetration of other ingredients in the formulation.
Myristic acid isopropyl ester is not recommended for particularly thin hair, as it can make it appear greasy, or an oily scalp or hair, as it can lead to clogged pores


-Applications of Myristic acid isopropyl ester:
*After Sun
*Antiperspirants & Deodorants
*Baby Care and Cleansing
*Body Care
*Color Care
*Conditioning
*Face Care
*Face Cleansing
*Personal Care Wipes
*Self Tanning
*Sun Protection


-Relevant identified uses of Myristic acid isopropyl ester:
Myristic acid isopropyl ester is used as Personal care product.
Myristic acid isopropyl ester is used in cosmetic creams and topical medicinals.


-Uses & Applications of Myristic acid isopropyl ester:
*Personal Care and Cosmetics
*Emollient, Moisturizer, Thickening Agent in Creams and Lotions
*Pharmaceuticals
*Thickening Agent, Emollient, Moisturizer in Topical Medicinal *Preparations
*Flavor and Fragrance
*Solvent, Binder, Diluent



BENEFITS OF MYRISTIC ACID ISOPROPYL ESTER:
*Superior emollient for non-greasy bath, body and baby oils
*Lubricant and compression aid for pressed powders
*Light & non-tacky emollient for creams and lotions. Readily adsorbed by the skin
*When used at high concentrations it gently lifts makeup and surface dirt
*Gives gloss and shine to hair
*Resistant to oxidation (does not become rancid)
*Widely used as diluent for fragrance oils.



FUNCTIONS OF MYRISTIC ACID ISOPROPYL ESTER:
1. Emollient - Softens and soothes the skin. Helps with skin conditioning.
2. Flavor / Flavoring / Flavor Enhancer - Provides or enhances a particular taste or smell.
3. Fragrance / Fragrance Component - Provides or enhances a particular smell or odor.



WHAT DOES MYRISTIC ACID ISOPROPYL ESTER DO IN A FORMULATION?
*Emollient
*Perfuming
*Skin conditioning
*Viscosity controlling



WHAT DOES MYRISTIC ACID ISOPROPYL ESTER 98% MEAN?
Myristic acid isopropyl ester 98% means that the mass fraction is 0.98.
In other words, in a sample of 100 g Myristic acid isopropyl ester 98% the mass of 98 g Myristic acid isopropyl ester is present.



PHYSICAL and CHEMICAL PROPERTIES of MYRISTIC ACID ISOPROPYL ESTER:
Molar mass: 270.457 g·mol−1
Density: 0.85 g/cm3
Boiling point: 167 °C (333 °F; 440 K) at 9 mmHg
Molecular Weight: 270.5
XLogP3-AA: 7.2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 14
Exact Mass: 270.255880323
Monoisotopic Mass: 270.255880323
Topological Polar Surface Area: 26.3 Ų
Heavy Atom Count: 19
Formal Charge: 0

Complexity: 199
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Boiling point: 140 °C (3 hPa)
Density: 0.85 g/cm3 (20 °C)
Flash point: >150 °C
Ignition temperature: >300 °C

Vapor pressure: Solubility: ΔfG°: -144.10 kJ/mol
ΔfH°gas: -644.29 kJ/mol
ΔfusH°: 39.05 kJ/mol
ΔvapH°: 62.20 kJ/mol
log10WS: -5.91
logPoct/wat: 5.639
McVol: 257.830 ml/mol
Pc: 1279.16 kPa
Appearance: colorless clear oily liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.84000 to 0.86000 @ 25.00 °C.

Pounds per Gallon - (est).: 6.990 to 7.156
Refractive Index: 1.42800 to 1.44300 @ 20.00 °C.
Melting Point: 2.00 to 3.00 °C. @ 760.00 mm Hg
Boiling Point: 192.00 to 193.00 °C. @ 20.00 mm Hg
Acid Value: 1.00 max. KOH/g
Saponification Value: 207.00
Vapor Pressure: 0.000329 mmHg @ 25.00 °C. (est)
Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 7.253 (est)
Shelf Life: 24.00 month(s) or longer if stored properly.

Storage: store in cool, dry place in tightly sealed containers,
protected from heat and light.
Soluble in: amyris wood oil, benzyl benzoate, benzyl salicylate, clove leaf oil,
deluent for candle fragrances, ethyl acetoacetate, ethyl lactate,
paraffin oil, water, 0.01354 mg/L @ 25 °C (est)
Insoluble in: water
Similar Items:note
isoamyl myristate
butyl myristate
isobutyl myristate
ethyl myristate
hexyl myristate

Physical state: clear, liquid
Color: light yellow
Odor: No data available
Melting point/freezing point:
Melting point/range: 3 °C
Initial boiling point and boiling range: 193 °C at 27 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 152 °C - closed cup
Autoignition temperature: 225 °C
Decomposition temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: 3,932 mm2/s at 40 °C
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: log Pow: 7,71
Vapor pressure: 0,0001246 hPa at 25 °C
Density: 0,85 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available

Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Appearance: A colorless or slightly yellow oily liquid
Ester content %: ≥98
Acid value(mg KOH/g): ≤0.5
Hazen(Color): ≤30
Refractive index: 1.434-1.438
Specific gravity(20℃): 0.850-0.855



FIRST AID MEASURES of MYRISTIC ACID ISOPROPYL ESTER:
-Description of first-aid measures:
*General advice:
Consult a physician.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of MYRISTIC ACID ISOPROPYL ESTER:
-Personal precautions, protective equipment and emergency procedures:
Use personal protective equipment.
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of MYRISTIC ACID ISOPROPYL ESTER:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available


EXPOSURE CONTROLS/PERSONAL PROTECTION of MYRISTIC ACID ISOPROPYL ESTER:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of MYRISTIC ACID ISOPROPYL ESTER:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.


STABILITY and REACTIVITY of MYRISTIC ACID ISOPROPYL ESTER:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
Propan-2-yl tetradecanoate
Tetradecanoic acid, 1-methylethyl ester
Myristic acid isopropyl ester
ISOPROPYL MYRISTATE
110-27-0
Isopropyl tetradecanoate
Tetradecanoic acid, 1-methylethyl ester
Estergel
Bisomel
Isomyst
Promyr
Deltyl Extra
propan-2-yl tetradecanoate
Kesscomir
Tegester
Wickenol 101
Sinnoester MIP
Crodamol IPM
Plymoutm IPM
Stepan D-50
Starfol IPM
Unimate IPM
Kessco IPM
Emcol-IM
Myristic acid isopropyl ester
Emerest 2314
1-Methylethyl tetradecanoate
JA-FA IPM
FEMA No. 3556
Kessco isopropyl myristate
Crodamol I.P.M.
Tetradecanoic acid, isopropyl
Myristic acid, isopropyl ester
Isopropyl myristate
Tetradecanoic acid, isopropyl ester
HSDB 626
NSC 406280
1-Tridecanecarboxylic acid, isopropyl ester
Isopropyl tetradecanoic acid
Estergel (TN)
methylethyl tetradecanoate
0RE8K4LNJS
iso-Propyl N-tetradecanoate
NSC-406280
CHEBI:90027
Tetradecanoic acid methyethyl ester
1405-98-7
NCGC00164071-01
Deltylextra
WE(2:0(1Me)/14:0)
DSSTox_CID_6838
Isopropyl myristate, 98%
DSSTox_RID_78224
DSSTox_GSID_26838
Caswell No. 511E
CAS-110-27-0
EINECS 203-751-4
UNII-0RE8K4LNJS
MFCD00008982
EPA Pesticide Chemical Code 000207
BRN 1781127
Tegosoft M
Isopropyl myristate [USAN:NF]
Liponate IPM
Crodamol 1PM
isopropyl-myristate
Lexol IPM
Isopropyltetradecanoate
myristic acid isopropyl
Radia 7190
Isopropyl myristate (NF)
EC 203-751-4
SCHEMBL2442
component of Sardo Bath Oil
Myristic acid-isopropyl ester
Isopropyl myristate, >=98%
CHEMBL207602
IPM 90
DTXSID0026838
WLN: 13VOY1&1
FEMA 3556
tetradecanoic acid isopropyl ester
ZINC8214588
Isopropyl myristate, >=90% (GC)
Tox21_112080
Tox21_202065
Tox21_303171
LMFA07010677
NSC406280
s2428
AKOS015902296
Tox21_112080_1
DB13966
component of Sardo Bath Oil (Salt/Mix)
NCGC00164071-02
NCGC00164071-03
NCGC00256937-01
NCGC00259614-01
LS-14615
DB-040910
HY-124190
CS-0085813
FT-0629053
M0481
MYRISTIC ACID, ISOPROPYL ALCOHOL ESTER
D02296
F71211
TETRADECONOIC ACID, 1-METHYLETHYL ESTER
EN300-25299830
Q416222
SR-01000944751
Isopropyl myristate, Vetec(TM) reagent grade, 98%
Q-201418
SR-01000944751-1
TETRADECANOIC ACID,ISOPROPYL ESTER (MYRISTATE,ISOPROPYL ESTER)
ISOPROPYL TETRADECANOATE
TETRADECENOIC ACID, 1-METHYLETHYL ESTER
MYRISTIC ACID, ISOPROPYL ESTER
Myristinsαure
NAA104
NAA142
Neo-Fat 14
neo-fat14
n-Myristicacid
n-Tetradecan-1-oic acid
n-tetradecan-1-oicacid
Myristic Acid Isopropyl Ester
1-Methylethyl tetradecanoate
Bisomel
Crodacol IPM
Crodamol IPM
D 50; D 50 (emollient)
Deltyl Extra
Emcol IM
Emerest 2314
Estol 1512
Estol 1514
Estol IPM 1512
Exceparl IPM
IPM
IPM 100
IPM-EX
IPM-R
Isomyst
Isopropyl myristate
Isopropyl myristate-PM
Isopropyl tetradecanoate
Kessco IPM
Kesscomir
Kollicream IPM
Lexol IPM
Liponate IPM
Matlube IPM-S
NSC 406280
Nikkol IPM
Nikkol IPM 100
Nikkol IPM-EX
Pastell IP 14
Pelemol IPM
Promyr
Radia 7190
Rilanit IPM
Sinnoester MIP
Stepan D 50
Stepan IPM
Tegosoft M
Wickenol 101
Bisomel
Stepan D-50
propan-2-yl tetradecanoate
Tegester
Kessco isopropyl myristate
Emerest 2314
Myristic acid, isopropyl ester
IPM-R
Plymoutm IPM
iso-Propyl Myristate
Isopropyl myristate (NF)
Ja-fa IPM
1-Tridecanecarboxylic acid, isopropyl ester
Estol IPM 1512
Isopropyl tetradecanoate
Tetradecanoic acid, isopropyl ester
Tetradecanoic acid,esters,1-methylethyl ester
Estergel (TN)
component of Sardo Bath Oil
Wickenol 101
Estergel
Unimate IPM
Sinnoester MIP
Kesscomir
Isomyst
Tetradecanoic acid, isopropyl
Promyr
Isopropylmyristate
Myristic acid isopropyl ester
IPM
IPM 100
IPM-EX
IPM-R
Isopropyl tetradecanoate
Myristic acid isopropyl ester
1-Methylethyl tetradecanoate
1-Tridecanecarboxylic acid, isopropyl ester
Bisomel
Crodamol I.P.M.
Crodamol IPM
D 50
Deltyl Extra
Emcol-IM
Emerest 2314
Estergel
IPM
Isomyst
Isopropyl tetradecanoate
Ja-fa IPM
Kessco IPM
Kessco isopropyl myristate
Kesscomir
Lexol IPM
Liponate IPM
Methylethyl tetradecanoate
Myristic acid, isopropyl ester
NSC 406280
Plymoutm IPM
Promyr
Radia 7190
Sinnoester MIP
Starfol IPM
Stepan D-50
Tegester
Tegosoft M
Tetradecanoic acid methyethyl ester
Tetradecanoic acid, 1-methylethyl ester
Tetradecanoic acid, isopropyl
Tetradecanoic acid, isopropyl ester
Unimate IPM
Wickenol 101
iso-Propyl N-tetradecanoate
Myristic acid isopropyl ester
Isopropyl tetradecanoate
Propan-2-yl tetradecanoate
Tetradecanoic acid, 1-methylethyl ester
Isopropyl myristate
Myristic acid, isopropyl ester
Tetradecanoic acid, isopropyl ester
Tetradecanoic acid, 1-methylethyl ester
Isopropyl tetradecanoate
1-Methylethyl tetradecanoate
Tetradecanoic acid, isopropyl
1-Tridecanecarboxylic acid, isopropyl ester
Myristic acid, isopropyl ester (8CI)
1-tridecanecarboxylic acid
iso-propyl N-tetradecanoate
isopropyl tetradecanoate
isopropyl tetradecanoic acid
myristic acid, 1-methyl ethyl ester
myristic acid
isopropyl ester
propan-2-yl tetradecanoate
tetradecanoic acid
1-methyl ethyl ester
tetradecanoic acid
isopropyl ester
isopropyl myristate
myristic acid isopropyl ester



MYRISTYL ALCOHOL
MYRISTYL AMINE OXIDE; Myristyl Dimethylamine; 1-(Dimethylamino)tetradecane; Dimethyl(Tetradecyl)Amine; Myristyl dimethylamine; cas no: 112-75-4
MYRISTYL ALCOHOL
DESCRIPTION:

Myristyl alcohol or 1-Tetradecanol,(from Myristica fragrans – the nutmeg plant), is a straight-chain saturated fatty alcohol, with the molecular formula CH3(CH2)12CH2OH.
Myristyl alcohol is a white waxy solid that is practically insoluble in water, soluble in diethyl ether, and slightly soluble in ethanol.
Myristyl Alcohol is a very useful ingredient in the cosmetic and personal care industry.


CAS Number: 112-72-1
EC Number: 204-000-3

Myristyl Alcohol is commonly used as an emollient as Myristyl Alcohol helps to hydrate and soothe the skin leaving Myristyl Alcohol healthier and better textured.
Myristyl Alcohol also reduces the surface tension between different components and helps to combine oil and water-based ingredients together.
Overall, Myristyl Alcohol improves the feel, texture, and performance of different products such as body lotions, lip balms, shampoos, and sunscreens.
The chemical formula of Myristyl Alcohol is C14H30O.

Myristyl alcohol is a 14-carbon, straight-chain, fatty alcohol made through the hydrogenation of Myristic Acid.
Myristic acids are found in palm kernel oil, nutmeg, and coconut oil.
Myristyl alcohol helps with major hair concerns such as dry, frizzy, dull hair and itchy scalp.
This waxy, white crystalline solid is insoluble in water but readily dissolves in ethanol and diethyl ether.

Myristic Acid is derived from nutmeg (Myristica Fragrans), from which its name is derived.
Myristyl alcohol is also found in coconut oil and palm kernel oil.
Myristyl Alcohol is used in various hair care products because of its emollient properties and emulsion stabilizer properties.
Myristyl alcohol is used to moisturize the skin and keep the soluble ingredients together in some skincare products.




PRODUCTION OF MYRISTYL ALCOHOL:
Myristyl alcohol may be prepared by the hydrogenation of myristic acid (or its esters); myristic acid itself can be found in nutmeg (from where Myristyl Alcohol gains its name) but is also present in palm kernel oil and coconut oil and Myristyl Alcohol is from these that the majority of 1-tetradecanol is produced.
Myristyl alcohol may also be produced from petrochemical feedstocks via either the Ziegler process.


USES OF MYRISTYL ALCOHOL:

As with other fatty alcohols, Myristyl alcohol is used as an ingredient in cosmetics such as cold creams for its emollient properties.
Myristyl alcohol is also used as an intermediate in the chemical synthesis of other products such as surfactants.

WHAT IS MYRISTYL ALCOHOL USED FOR?
Myristyl Alcohol is a common ingredient and cosmetics and personal care products because of its conditioning and moisturizing properties.

Skin care: Myristyl Alcohol is used for its emollient properties to soften and smoothen the surface.
Further, Myristyl Alcohol stabilizes formulations and improves the texture of the products.
Myristyl Alcohol is also a thickener that increases the viscosity of skin care products and makes them easier to apply

Hair care: Myristyl Alcohol is a great conditioning agent for hair care products like shampoos, conditioners, and styling products.
Myristyl Alcohol is also a surfactant that helps in removing oil and dirt from the scalp and shafts

ORIGIN OF MYRISTYL ALCOHOL:
Myristyl Alcohol is derived from natural sources like palm kernel oil, coconut oil, or other vegetable oils.
For this procedure, myristic acid is hydrogenated in the presence of a catalyst such as palladium or nickel.
Myristyl Alcohol can be in the form of a white waxy solid, flakes, or powder.

BENEFITS OF MYRISTYL ALCOHOL IN HAIRCARE:
This light-weight fatty alcohol functions as a thickener, emulsion, emollient, texture enhancer, and stabilizer in your product formula.
Myristyl Alcohol is used in hair care products to improve the texture and manageability of your hair.

1. Emulsifier:
In addition to binding water and oil together, myristyl alcohol prevents the ingredients in the formula from separating.
An emulsifier plays a crucial role in keeping the ingredients in the product formula from becoming clumpy.

2. Emollient :
This plant-derived fatty alcohol exhibits a moisturizing and smoothening effect on your hair.
Unlike short chain alcohols, they won't dry out your hair.
Myristyl alcohol keeps your hair soft, smooth, and hydrated.

3. Surfactant :
Myristyl Alcohol acts as a natural surfactant in hair care products by binding with dirt, oil, and other impurities and effectively eliminating it from your hair and scalp.
Myristyl Alcohol gently cleanses your scalp and hair without disturbing your scalp's pH balance.

Myristyl Alcohol prevents buildup, making your scalp clean and well hydrated.
Myristyl Alcohol reduces the surface tension between two liquids, making it easier to wash off dirt, dust, and grime from the hair and scalp.

4. Foam boasting :
Its foam boasting property helps create rich, thick lather, improving the product's efficacy. Getting rid of the gunk becomes much easier, leaving you feeling clean and refreshed.

5. Viscosity controlling agents :
Myristyl Alcohol enhances the viscosity of haircare products by thickening them.
Myristyl Alcohol improves the consistency of your hair care product by giving the product a rich, thick, and creamy texture.

6. Maintains healthy scalp :
As an emollient, myristyl alcohol maintains the moisture of your scalp and hair.
Myristyl Alcohol improves the hydration level of your scalp by locking the moisture inside, keeping your scalp hydrated for a longer time.

Myristyl Alcohol has a soothing effect on your dry, itchy, and flaky scalp.
Regular use improves the scalp's barrier function, thus maintaining scalp health.

HOW TO USE MYRISTYL ALCOHOL IN HAIRCARE?
Myristyl Alcohol reduces moisture loss by forming a thin film over the surface and trapping the moisture inside your hair.
Myristyl Alcohol conditions your hair, making your hair look smooth and glossy.
Myristyl Alcohol gives the slip to the product, allowing it to glide through your hair, thus improving its spreadability.
Myristyl alcohol has a conditioning and detangling effect on your hair.
Myristyl Alcohol gives bounce and volume to your hair.

As a thickening agent, Myristyl Alcohol improves the consistency of your hair care product, making it look more appealing to your senses.
As an emulsifying agent, Myristyl Alcohol gives stability to the product by preventing the ingredients in the formula from separating, thus prolonging the product's shelf life.

HOW TO CHOOSE MYRISTYL ALCOHOL IN HAIRCARE?
Myristyl alcohol is also known as tetradecyl alcohol, tetradecan-1-ol, 1-Tetradecanol, 1-Hydroxytetradecane.
When choosing hair care products look for these terms on the label.

WHAT DOES MYRISTYL ALCOHOL DO IN A FORMULATION?
Emollient
Emulsion stabilising
Foam boosting
Skin conditioning
Viscosity controlling

SAFETY INFORMATION ABOUT MYRISTYL ALCOHOL:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.

CHEMICAL AND PHYSICAL PROPERTIES OF MYRISTYL ALCOHOL:
Chemical formula C14H30O
Molar mass 214.393 g•mol−1
Density 0.824 g/cm3
Melting point 38 °C (100 °F; 311 K)
Boiling point >260 °C
Molecular Weight 214.39 g/mol
XLogP3 6.2
Computed by XLogP3 3.0 (PubChem release 2021.05.07)
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 1
Rotatable Bond Count 12
Exact Mass 214.229665576 g/mol
Monoisotopic Mass 214.229665576 g/mol
Topological Polar Surface Area 20.2Ų
Heavy Atom Count 15
Formal Charge 0
Complexity 102
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
Appearance: white liquid to solid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.81900 to 0.82500 @ 25.00 °C.
Pounds per Gallon - (est).: 6.815 to 6.865
Refractive Index: 1.43500 to 1.44100 @ 20.00 °C.
Melting Point: 36.00 to 40.00 °C. @ 760.00 mm Hg
Boiling Point: 289.00 °C. @ 760.00 mm Hg
Acid Value: 1.00 max. KOH/g
Vapor Pressure: 0.001000 mmHg @ 25.00 °C. (est)
Vapor Density: 7.4 ( Air = 1 )
Flash Point: 258.00 °F. TCC ( 125.56 °C. )
logP (o/w): 6.030
Soluble in:
alcohol
water, 0.8449 mg/L @ 25 °C (est)
water, 0.191 mg/L @ 25 °C (exp)
Insoluble in:
Water

SPECIFICATION OF MYRISTYL ALCOHOL:
Acid Value (mg KOH/g) 0.1 Max
Saponification Value (mg KOH/g) 0.5 Max
Iodine Value (% I2absorbed) 0.3 Max
Hydroxyl Value (mgKOH/g) 255-262
Color (APHA) 10 Max
Moisture Content (%) 0.1 Max
Fatty Alcohol Content (%) 99 Min

SYNONYMS OF MYRISTYL ALCOHOL:
1-tetradecanol
myristyl alcohol
myristyl alcohol, aluminum salt
tetradecan-1-ol
1-TETRADECANOL
Tetradecan-1-ol
112-72-1
Myristyl alcohol
Tetradecanol
Tetradecyl alcohol
n-Tetradecanol
Myristic alcohol
n-Tetradecyl alcohol
Lanette K
Loxanol V
n-Tetradecanol-1
1-Hydroxytetradecane
Alfol 14
n-Tetradecan-1-ol
Dytol R-52
Lanette 14
1-Tetradecyl alcohol
tetradecan1-ol
NSC 8549
Polyethylene monoalcohol
Myristyl alcohol [NF]
NSC-8549
71750-71-5
63393-82-8
67762-41-8
68855-56-1
DTXSID9026926
CHEBI:77417
N-TETRADECYL-D29 ALCOHOL
V42034O9PU
kalcohl 40
75782-87-5
Myristyl alcohol (NF)
C14 alcohol
68002-95-9
DTXCID406926
Alcohol(C14)
CAS-112-72-1
Tetradecanol (7CI)
Kalcohl 4098
C14-15 alcohol
HSDB 5168
Lorol C 14
Adol 18
Kalcol 4098
Conol 1495
EINECS 204-000-3
MFCD00004757
Nacol 14-95
BRN 1742652
UNII-S4827SZE3L
UNII-V42034O9PU
tetradecylalcohol
AI3-00943
Tetradecanol-1
EINECS 267-019-6
EINECS 268-107-7
EINECS 272-490-6
EINECS 275-983-4
Philcohol 1400
Lorol C14
Myristyl cetyl alcohol
Epal 14
1-Tetradecanol, 97%
SDA 15-060-00
EC 204-000-3
EC 616-261-4
SCHEMBL20286
4-01-00-01864 (Beilstein Handbook Reference)
CHEMBL24022
MYRISTYL ALCOHOL [II]
MYRISTYL ALCOHOL [MI]
MYRISTYL ALCOHOL [FCC]
S4827SZE3L
WLN: Q14
MYRISTYL ALCOHOL [HSDB]
MYRISTYL ALCOHOL [INCI]
MYRISTYL ALCOHOL [MART.]
NSC8549
MYRISTYL ALCOHOL [USP-RS]
MYRISTYL ALCOHOL [WHO-DD]
14 OH
EINECS 267-009-1
EINECS 269-790-4
Tox21_201842
Tox21_300538
LMFA05000041
STL453593
AKOS009031495
CS-W004294
HY-W004294
NCGC00164345-01
NCGC00164345-02
NCGC00164345-03
NCGC00254322-01
NCGC00259391-01
BP-30124
1-Tetradecanol, purum, >=95.0% (GC)
FT-0608311
T0084
EN300-19955
1-Tetradecanol, Selectophore(TM), >=99.0%
D05097
D77653
1-Tetradecanol, Vetec(TM) reagent grade, 97%
A894532
Q161683
F7FCB87C-0FA4-412A-BC8C-BE5C952BC1E0
J-002824
Myristyl alcohol, United States Pharmacopeia (USP) Reference Standard
Myristyl Alcohol, Pharmaceutical Secondary Standard; Certified Reference Material




MYRISTYL ALCOHOL (C14)
Obtained from palm kernel or coconut oil fatty acids by esterification and catalytic hydrogenation.
Classified as a mid-cut alcohol is a white crystalline solid below 36-39 ºC.
Myristyl Alcohol (C14) occurs as a white crystalline solid with a waxy odor.

CAS: 112-72-1
MF: C14H30O
MW: 214.39
EINECS: 204-000-3

Also reported as opaque leaflets or crystals from ethanol.
1-Tetradecanol, or commonly Myristyl Alcohol (C14), is a straight-chain saturated fatty alcohol, with the molecular formula CH3(CH2)12CH2OH.
Myristyl Alcohol (C14) is a white waxy solid that is practically insoluble in water, soluble in diethyl ether, and slightly soluble in ethanol.
As with other fatty alcohols, Myristyl Alcohol (C14) is used as an ingredient in cosmetics such as cold creams for its emollient properties.
Myristyl Alcohol (C14) is also used as an intermediate in the chemical synthesis of other products such as surfactants.
Myristyl Alcohol (C14) may be prepared by the hydrogenation of myristic acid (or its esters); Myristyl Alcohol (C14) itself can be found in nutmeg (from where it gains its name) but is also present in palm kernel oil and coconut oil and it is from these that the majority of 1-tetradecanol is produced.

Myristyl Alcohol (C14) may also be produced from petrochemical feedstocks via either the Ziegler process.
Myristyl Alcohol (C14) is a long-chain fatty alcohol that is tetradecane substituted by a hydroxy group at position 1.
Myristyl Alcohol (C14) has a role as a plant metabolite, a volatile oil component and a pheromone.
Myristyl Alcohol (C14) is a long-chain primary fatty alcohol and a tetradecanol.
Myristyl Alcohol (C14) is a natural product found in Mikania cordifolia, Hypericum hyssopifolium, and other organisms with data available.
Myristyl Alcohol (C14) is a colorless thick liquid (heated) with a faint alcohol odor. Solidifies and floats on water.
Myristyl Alcohol (C14) is a kind of straight-chain saturated fatty alcohol.

Myristyl Alcohol (C14) is often used as an ingredient in cosmetics such as cold creams because of its emollient properties.
Myristyl Alcohol (C14) can also be used as the intermediate during the manufacturing of some organic compounds like surfactants.
Some studies have shown that Myristyl Alcohol (C14) can inhibit the endothelial activation and reduce tissue responsiveness to cytokines, having the potential to treat the periodontitis based on studies on rabbits.
Myristyl Alcohol (C14) is also employed for the fabrication of temperature-regulated drug release system based on phase-change materials.
Myristyl Alcohol (C14) is a long-chain fatty alcohol that is tetradecane in which one of the terminal methyl hydrogens is replaced by a hydroxy group
Myristyl Alcohol (C14) is a long-chain primary fatty alcohol, a fatty alcohol 14:0 and a primary alcohol.

Myristyl Alcohol (C14) Chemical Properties
Melting point: 35-39 °C(lit.)
Boiling point: 289 °C(lit.)
Density: 0.823 g/mL at 25 °C(lit.)
Vapor density: 7.4 (vs air)
Vapor pressure: Refractive index: 1.4454
Fp: >230 °F
Storage temp.: Store below +30°C.
Solubility water: soluble0.00013g/L at 23°C
Form: Low Melting Solid, Crystalline Powder, Crystals, Flakes, Pellets and/or Chunks
Pka: 15.20±0.10(Predicted)
Specific Gravity: 0.823
Color: White
Odor: fatty
Odor Type: waxy
Water Solubility: insoluble
Merck: 14,6335
BRN: 1742652
Dielectric constant: 4.4(48℃)
LogP: 5.5
CAS DataBase Reference: 112-72-1(CAS DataBase Reference)
NIST Chemistry Reference: Myristyl Alcohol (C14)(112-72-1)
EPA Substance Registry System: Myristyl Alcohol (C14) (112-72-1)

Uses
Myristyl Alcohol (C14) is an emollient often used in hand creams, cold creams, and lotions to give them a smooth, velvety feel.
Sources indicate Myristyl Alcohol (C14) as being mildly comedogenic and potentially irritating.
Myristyl Alcohol (C14) is used as an ingredient in cosmetics such as cold creams.
Myristyl Alcohol (C14) is an active intermediate in the chemical synthesis of sulfated alcohol.
Myristyl Alcohol (C14) is also employed in the fabrication of temperature-regulated drug release system based on phase-change materials.
Myristyl Alcohol (C14) plays a vital role in filling the hollow interiors of gold nanocages in the fabrication of new theranostic system, which has unique feature of photoacoustic imaging.
As emollient for cold creams, etc., also for making the sulfated alcohol whose sodium salt is applicable as a "wetter" in textiles.

Myristyl Alcohol (C14) is a chemical compound that has been used as a model system for studying the biochemical properties of long-chain alcohols.
Myristyl Alcohol (C14) has been shown to be a potent antimicrobial agent, with activity against Gram-positive bacteria and Candida albicans.
Myristyl Alcohol (C14) is soluble in trifluoroacetic acid and insoluble in water.
The phase transition temperature for Myristyl Alcohol (C14) can be determined using an analytical method such as differential scanning calorimetry or by measuring its melting point.
Myristyl Alcohol (C14) is also used in the study of infectious diseases, including galleria mellonella and Linoleyl alcohol.

Pharmaceutical Applications
Myristyl Alcohol (C14) is used in oral, parenteral, and topical pharmaceutical formulations.
Myristyl Alcohol (C14) has been evaluated as a penetration enhancer in melatonin transdermal patches in rats.
Myristyl Alcohol (C14) has also been tested as a bilayer stabilizer in niosome formulations containing ketorolac tromethamine,and zidovudine.
Niosomes containing Myristyl Alcohol (C14) showed a considerably slower release rate of ketorolac tromethamine than those containing cholesterol.
This was also observed with the zidovudine formulation.

Production Methods
Myristyl Alcohol (C14) is found in spermaceti wax and sperm oil, and may be synthesized by sodium reduction of fatty acid esters or the reduction of fatty acids by lithium aluminum hydride.
Myristyl Alcohol (C14) can also be formed from acetaldehyde and dimethylamine.

Synonyms
1-TETRADECANOL
Tetradecan-1-ol
112-72-1
Myristyl alcohol
Tetradecanol
Tetradecyl alcohol
n-Tetradecanol
Myristic alcohol
n-Tetradecyl alcohol
Lanette K
Loxanol V
n-Tetradecanol-1
1-Hydroxytetradecane
Alfol 14
n-Tetradecan-1-ol
Dytol R-52
Lanette 14
1-Tetradecyl alcohol
tetradecan1-ol
NSC 8549
Polyethylene monoalcohol
Myristyl alcohol [NF]
NSC-8549
68855-56-1
71750-71-5
63393-82-8
67762-41-8
DTXSID9026926
CHEBI:77417
V42034O9PU
N-TETRADECYL-D29 ALCOHOL
kalcohl 40
75782-87-5
Myristyl alcohol (NF)
C14 alcohol
68002-95-9
DTXCID406926
Alcohol(C14)
CAS-112-72-1
Tetradecanol (7CI)
Kalcohl 4098
C14-15 alcohol
HSDB 5168
Lorol C 14
Adol 18
Kalcol 4098
Conol 1495
EINECS 204-000-3
MFCD00004757
Nacol 14-95
BRN 1742652
UNII-S4827SZE3L
UNII-V42034O9PU
tetradecylalcohol
AI3-00943
Tetradecanol-1
EINECS 267-019-6
EINECS 268-107-7
EINECS 272-490-6
EINECS 275-983-4
Philcohol 1400
Lorol C14
Myristyl cetyl alcohol
Epal 14
1-Tetradecanol, 97%
SDA 15-060-00
EC 204-000-3
EC 616-261-4
SCHEMBL20286
4-01-00-01864 (Beilstein Handbook Reference)
CHEMBL24022
MYRISTYL ALCOHOL [II]
MYRISTYL ALCOHOL [MI]
MYRISTYL ALCOHOL [FCC]
S4827SZE3L
WLN: Q14
MYRISTYL ALCOHOL [HSDB]
MYRISTYL ALCOHOL [INCI]
MYRISTYL ALCOHOL [MART.]
NSC8549
MYRISTYL ALCOHOL [USP-RS]
MYRISTYL ALCOHOL [WHO-DD]
14 OH
EINECS 267-009-1
EINECS 269-790-4
Tox21_201842
Tox21_300538
LMFA05000041
Myristyl alcohol; n-Tetradecan-1-ol
AKOS009031495
CS-W004294
HY-W004294
NCGC00164345-01
NCGC00164345-02
NCGC00164345-03
NCGC00254322-01
NCGC00259391-01
BP-30124
1-Tetradecanol, purum, >=95.0% (GC)
FT-0608311
T0084
EN300-19955
1-Tetradecanol, Selectophore(TM), >=99.0%
D05097
D77653
1-Tetradecanol, Vetec(TM) reagent grade, 97%
A894532
Q161683
F7FCB87C-0FA4-412A-BC8C-BE5C952BC1E0
J-002824
Myristyl alcohol, United States Pharmacopeia (USP) Reference Standard
Myristyl Alcohol, Pharmaceutical Secondary Standard; Certified Reference Material
MYRISTYL AMINE OXIDE


Myristyl amine oxide is an amphoteric surfactant, meaning it exhibits both surfactant and detergent properties.
Myristyl amine oxide is derived from the reaction between myristyl alcohol and dimethylamine oxide.
Myristyl amine oxide consists of a hydrophilic (water-loving) head group containing the dimethylamine oxide functionality and a lipophilic (fat-loving) tail group consisting of the myristyl chain.

CAS Number: 3332-27-2
EC Number: 222-970-5



APPLICATIONS


Myristyl amine oxide is used as a surfactant and foam booster in personal care products like shampoos, conditioners, and body washes.
Myristyl amine oxide functions as an emulsifier in creams, lotions, and cosmetic formulations, aiding in the uniform blending of ingredients.

Myristyl amine oxide is utilized as a wetting agent in agricultural formulations to ensure effective coverage and absorption of pesticides and fertilizers on plant surfaces.
Myristyl amine oxide is employed as a foam stabilizer in foam bath products, shaving creams, and foaming cleansers, providing a luxurious and long-lasting lather.
Myristyl amine oxide acts as a dispersing agent in paint and coating formulations, ensuring the uniform distribution of pigments and additives for optimal performance.

Myristyl amine oxide finds application in metalworking fluids as an emulsifier, improving lubrication and cooling properties during machining processes.
Myristyl amine oxide serves as an emulsifier and stabilizer in emulsion polymerization processes, enabling the production of latexes used in adhesives, paints, and coatings.
Myristyl amine oxide is used in the production of firefighting foams, providing foam stabilization and wetting properties for effective fire suppression.

Myristyl amine oxide is employed as a corrosion inhibitor in various applications to protect metal surfaces from degradation and rust formation.
Myristyl amine oxide acts as a leveling and dispersing agent in textile processing, ensuring even dyeing and improved color dispersion in fabrics.

Myristyl amine oxide finds use in industrial cleaning applications, such as metal degreasing and surface preparation, due to its effective removal of stubborn residues.
Myristyl amine oxide is incorporated into household cleaning products like dishwashing detergents and all-purpose cleaners, enhancing their grease-cutting and cleaning properties.
Myristyl amine oxide is used as an emulsifier and foam stabilizer in carpet cleaning formulations, promoting efficient soil removal and improving foam stability.

Myristyl amine oxide finds application in automotive cleaning products, aiding in the removal of grease, oil, and road grime from vehicle surfaces.
Myristyl amine oxide is utilized in adhesive formulations, improving wetting and bonding properties in applications such as tape and label adhesives.
Myristyl amine oxide is employed as a dispersing agent in ceramic and glass manufacturing, facilitating the even distribution of raw materials and enhancing product quality.

Myristyl amine oxide is used in the formulation of metal cleaners and degreasers, ensuring effective removal of oils, greases, and contaminants from metal surfaces.
Myristyl amine oxide finds application in agricultural chemicals as a surfactant and wetting agent, improving the spreading and absorption of crop protection products.
Myristyl amine oxide is utilized in the production of printing inks, aiding in pigment dispersion and providing excellent print quality on various substrates.

Myristyl amine oxide is incorporated into carpet and upholstery cleaners, assisting in the removal of stains and soiling from fabrics and fibers.
Myristyl amine oxide finds use in foam booster formulations for fire control and suppression, providing stable and long-lasting foam blankets.
Myristyl amine oxide is utilized in the formulation of water treatment chemicals, assisting in the dispersion and removal of organic contaminants.

Myristyl amine oxide finds application in industrial degreasers and solvent cleaners, facilitating the removal of tough oils, greases, and residues from equipment and machinery.
Myristyl amine oxide is used in leather and textile processing to improve dye penetration and leveling, resulting in consistent coloration.
Myristyl amine oxide is employed in household fabric care products like laundry detergents and fabric softeners, aiding in soil removal and fabric conditioning.

Myristyl amine oxide finds applications in a variety of industries and products.
Here are some of its main applications:

Personal Care Products:
Myristyl amine oxide is commonly used in personal care products such as shampoos, conditioners, body washes, facial cleansers, and hand soaps.
Myristyl amine oxide functions as a surfactant and foam booster, helping to create rich lather and enhance the cleansing properties of these products.

Household Cleaning Products:
Myristyl amine oxide is utilized in household cleaning products including dishwashing detergents, laundry detergents, and all-purpose cleaners.
Myristyl amine oxide helps to remove grease, dirt, and stains effectively.

Industrial Cleaners:
Myristyl amine oxide is employed in industrial cleaning formulations for applications such as metal cleaning, surface preparation, and degreasing.
Myristyl amine oxide aids in the removal of oils, greases, and other contaminants.

Textile Processing:
In the textile industry, myristyl amine oxide serves as a levelling and dispersing agent during fabric dyeing and printing processes.
Myristyl amine oxide helps to achieve uniform dyeing and improve color dispersion.

Agricultural Formulations:
Myristyl amine oxide finds use in agricultural formulations such as herbicides, insecticides, and fungicides.
Myristyl amine oxide aids in the dispersion and stability of active ingredients, enhancing the efficacy of these formulations.

Corrosion Inhibitors:
Myristyl amine oxide is utilized as a corrosion inhibitor in certain applications to protect metal surfaces from corrosion and rust formation.

Industrial Applications:
Myristyl amine oxide is used in various industrial applications where its surfactant and emulsifying properties are beneficial, including in metalworking fluids, paint strippers, and adhesive formulations.

Oilfield Chemicals:
Myristyl amine oxide finds application in oilfield chemicals, particularly in drilling and production operations.
Myristyl amine oxide is used as a surfactant and foam stabilizer in drilling fluids and as an emulsifier in oil-water separation processes.

Formulation Additive:
Myristyl amine oxide can be used as an additive in formulations to improve viscosity, stability, and overall performance.

Cosmetics and Personal Care:
Myristyl amine oxide is used in various cosmetic products such as creams, lotions, makeup, and hair care products.
Myristyl amine oxide can function as an emulsifier, thickener, and conditioning agent, providing desirable texture and sensory attributes.

Foam Stabilizer:
Myristyl amine oxide is employed as a foam stabilizer in various formulations, including foam bath products, shaving creams, and foaming cleansers.
Myristyl amine oxide helps to enhance the stability and longevity of foam structures.

Wetting Agent:
Myristyl amine oxide acts as a wetting agent in agricultural formulations, aiding in the uniform distribution and absorption of pesticides, herbicides, and fertilizers on plant surfaces.

Metalworking:
Myristyl amine oxide finds application in metalworking fluids as an emulsifier and corrosion inhibitor.
Myristyl amine oxide helps to improve the lubricity and cooling properties of cutting fluids, facilitating metal cutting and machining processes.

Paints and Coatings:
Myristyl amine oxide can be incorporated into paint and coating formulations as a dispersing agent and emulsifier.
Myristyl amine oxide assists in the uniform dispersion of pigments and additives, enhancing the overall performance and stability of the coatings.

Emulsion Polymerization:
Myristyl amine oxide is utilized in emulsion polymerization processes as a surfactant and emulsifier.
Myristyl amine oxide aids in the formation and stabilization of polymer emulsions, allowing for the production of latexes used in various applications, including adhesives, paints, and coatings.

Anti-Fogging Agent:
Myristyl amine oxide is sometimes employed as an anti-fogging agent in products such as goggles, mirrors, and windshields.
Myristyl amine oxide helps to prevent the formation of fog by reducing surface tension and promoting even spreading of moisture.

Firefighting Foam:
Myristyl amine oxide is used in firefighting foams as a foam stabilizer and wetting agent.
Myristyl amine oxide assists in the creation of stable and long-lasting foam blankets, improving the effectiveness of fire suppression efforts.

Industrial Cleaning:
Myristyl amine oxide is utilized in industrial cleaning applications such as metal degreasing, equipment cleaning, and surface preparation.
Myristyl amine oxide helps to remove stubborn residues and contaminants effectively.



DESCRIPTION


Myristyl amine oxide, also known as Tetradecyl dimethylamine oxide or N-Tetradecyl-N,N-dimethylamine N-oxide, is a chemical compound.
Its molecular formula is C14H31NO and it has a molar mass of approximately 229.41 grams/mol.

Myristyl amine oxide is an amphoteric surfactant, meaning it exhibits both surfactant and detergent properties.
Myristyl amine oxide is derived from the reaction between myristyl alcohol and dimethylamine oxide.
Myristyl amine oxide consists of a hydrophilic (water-loving) head group containing the dimethylamine oxide functionality and a lipophilic (fat-loving) tail group consisting of the myristyl chain.

Myristyl amine oxide is typically found in the form of a clear to pale yellow liquid or solid flakes, depending on the temperature.
Myristyl amine oxide is soluble in water and compatible with various organic solvents.

Myristyl amine oxide compound is commonly used as a surfactant and detergent in various personal care and household products.
Myristyl amine oxide acts as a foaming agent, emulsifier, viscosity builder, and cleaning agent.
Myristyl amine oxide is often found in shampoos, conditioners, body washes, facial cleansers, dishwashing detergents, and laundry detergents.

Due to its surfactant properties, myristyl amine oxide helps to remove dirt, oil, and other impurities from surfaces, allowing them to be easily rinsed away.
Myristyl amine oxide also helps to enhance the foaming and lathering properties of cleansing products, providing a luxurious and satisfying user experience.

Myristyl amine oxide is known for its mildness and low irritation potential, making it suitable for use in personal care products.
Myristyl amine oxide is also biodegradable and environmentally friendly.

Myristyl amine oxide is a versatile surfactant and detergent compound.
Myristyl amine oxide is derived from the reaction between myristyl alcohol and dimethylamine oxide.
Myristyl amine oxide has a hydrophilic head group and a lipophilic tail group.

Myristyl amine oxide is available as a clear to pale yellow liquid or solid flakes.
Myristyl amine oxide has a characteristic mild odor.
Myristyl amine oxide is soluble in water and compatible with various organic solvents.

Myristyl amine oxide acts as a foaming agent, emulsifier, and viscosity builder.
Myristyl amine oxide is commonly used in personal care products such as shampoos and body washes.
Myristyl amine oxide helps to remove dirt, oil, and impurities from surfaces.
Myristyl amine oxide enhances the foaming and lathering properties of cleansing products.

Myristyl amine oxide provides a luxurious and satisfying user experience in personal care routines.
Myristyl amine oxide is known for its mildness and low irritation potential.

Myristyl amine oxide is biodegradable and environmentally friendly.
Myristyl amine oxide is used in household cleaning products like dishwashing detergents.

Myristyl amine oxide helps to cut through grease and grime, providing effective cleaning.
Myristyl amine oxide is compatible with a wide range of formulation ingredients.

Myristyl amine oxide offers excellent stability in various pH ranges.
Myristyl amine oxide exhibits good wetting and dispersing properties.

Myristyl amine oxide can improve the viscosity and texture of formulations.
Myristyl amine oxide has a long shelf life when stored properly.
Myristyl amine oxide is commonly used in industrial applications such as metal cleaning.
Myristyl amine oxide is used in textile processing as a levelling and dispersing agent.
Myristyl amine oxide is also employed in agricultural formulations.

Myristyl amine oxide can be used as a corrosion inhibitor in certain applications.
Myristyl amine oxide undergoes thorough quality control measures to ensure its effectiveness and safety.



PROPERTIES


Chemical Formula: C14H31NO
Molecular Weight: Approximately 229.41 grams/mol
Physical State: Liquid or solid flakes
Appearance: Clear to pale yellow color
Odor: Mild characteristic odor
Solubility: Soluble in water
Density: Varies depending on the form (liquid or solid)
pH: Typically neutral to slightly acidic or basic
Boiling Point: Varies depending on the form (liquid or solid)
Melting Point: Varies depending on the form (liquid or solid)
Flash Point: Not applicable (non-flammable)
Vapor Pressure: Low vapor pressure
Viscosity: Varies depending on the concentration and temperature
Surface Tension: Low surface tension
Hydrophilicity: Amphiphilic (both hydrophilic and lipophilic properties)
Chemical Stability: Stable under normal conditions
Flammability: Non-flammable
Autoignition Temperature: Not applicable
Oxidizing Properties: Not known to possess oxidizing properties
Biodegradability: Biodegradable under appropriate conditions
Environmental Impact: Considered environmentally friendly
Compatibility: Compatible with a wide range of formulation ingredients
pH Stability: Stable over a broad pH range
Foaming Properties: Exhibits good foaming properties
Irritation Potential: Known for its mildness and low irritation potential



FIRST AID


General Advice:

Remove the person from the contaminated area and provide a safe environment.
If any symptoms persist or worsen, seek medical advice.
In case of large spills or exposure to a significant amount of the compound, contact emergency services or a poison control center for further guidance.


Inhalation:

Move the affected person to fresh air and ensure they are in a well-ventilated area.
If breathing is difficult, provide oxygen or artificial respiration as needed.
Seek immediate medical attention if symptoms persist or worsen.


Skin Contact:

Remove contaminated clothing and shoes.
Gently blot or wipe away excess product from the skin.
Wash the affected area thoroughly with mild soap and water for at least 15 minutes.
Rinse well to ensure complete removal of the compound.
If irritation occurs, seek medical advice and provide information about the product.


Eye Contact:

Rinse the eyes gently but thoroughly with water for at least 15 minutes, ensuring that the compound is flushed out from under the eyelids.
If wearing contact lenses, remove them after the initial rinse and continue rinsing.
Seek immediate medical attention, even if the person feels no discomfort or irritation.


Ingestion:

Do not induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth with water if the person is conscious and able to swallow.
Do not give anything by mouth to an unconscious person.
Seek immediate medical attention and provide relevant product information.



HANDLING AND STORAGE


Personal Protection:

Wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and protective clothing when handling Myristyl amine oxide.
Avoid direct skin contact and inhalation of vapors or mists.
Use respiratory protection if necessary.
Ensure good ventilation in the working area to minimize exposure to airborne particles.


Handling Precautions:

Handle Myristyl amine oxide in a well-ventilated area to prevent the accumulation of vapors.
Avoid open flames, sparks, or other potential sources of ignition, as the compound may be combustible.
Use appropriate containment measures (e.g., spill trays, absorbents) to prevent and control spills and leaks.
Do not eat, drink, or smoke while handling the compound.
Wash hands thoroughly with soap and water after handling.


Storage:

Store Myristyl amine oxide in a cool, dry, well-ventilated area away from direct sunlight and incompatible materials.
Keep containers tightly closed and properly labeled to prevent accidental exposure or ingestion.
Store away from sources of heat, ignition, and strong oxidizing agents.
Ensure proper segregation from acids, bases, and other incompatible substances.
Follow any specific storage recommendations provided on the product's safety data sheet (SDS).


Fire and Explosion Hazards:

Myristyl amine oxide is generally non-flammable and does not pose a significant fire hazard.
However, if involved in a fire, use standard firefighting procedures and extinguishing agents suitable for surrounding materials.


Spill and Leak Response:
In the event of a spill or leak, contain the material and prevent it from spreading.
Use appropriate absorbent materials to soak up the spilled substance.
Avoid contact with skin and eyes.
Wear suitable protective equipment as mentioned earlier.
Dispose of the spilled material and any contaminated absorbents in accordance with local regulations.


Disposal Considerations:

Dispose of Myristyl amine oxide in accordance with local, regional, and national regulations.
Consult with appropriate authorities or a licensed waste disposal company for guidance on proper disposal methods.



SYNONYMS


N-Tetradecyl-N,N-dimethylamine-N-oxide
Tetradecyl dimethylamine oxide
Tetradecyldimethylamine N-oxide
Myristamine oxide
Myristyl dimethylamine oxide
N-Myristyl-N,N-dimethylamine-N-oxide
N,N-Dimethyltetradecylamine N-oxide
N,N-Dimethylmyristylamine oxide
Dimethyl(myristyl)amine N-oxide
C14-16 Dimethylamine oxide
Myristyl dimethyl(ethyl)amine oxide
N,N-Dimethyl-N-tetradecylamine-N-oxide
N,N-Dimethyltetradecanamine oxide
Tetradecyl(dimethyl)amine oxide
Myristyl dimethyl amine N-oxide
Dimethyl(myristoyl)amine oxide
N,N-Dimethylmyristylamine N-oxide
Dimethyltetradecylamine N-oxide
N,N-Dimethyl-N-myristylamine N-oxide
Tetradecyl(dimethyl)aminoxide
Dimethyl myristamine oxide
N,N-Dimethyltetradecylamine N-oxide
Tetradecyl(dimethyl)amine N-oxide
Myristyl(dimethyl)amine N-oxide
N,N-Dimethyltetradecylamine oxide
Tetradecyldimethylamine-N-oxide
Myristoyl dimethylamine oxide
N,N-Dimethyltetradecylamine-N-oxide
Dimethyltetradecylamine oxide
N,N-Dimethylmyristamine N-oxide
N,N-Dimethyltetradecanamine N-oxide
Tetradecyldimethylaminoxide
Myristamine-N-oxide
Dimethyltetradecanamine-N-oxide
Tetradecyl(dimethyl)amine-N-oxide
N,N-Dimethylmyristamine oxide
Tetradecyl(dimethyl)aminoxide
Dimethyltetradecylamine N-oxide
N,N-Dimethyltetradecylamine-N-oxide
Dimethyltetradecylamine-N-oxide
Myristoyldimethylamine-N-oxide
N,N-Dimethyltetradecylamine N-oxide
Myristamine(dimethyl)amine oxide
Tetradecyldimethylamine-N-oxide
Myristoyldimethylamine N-oxide
N,N-Dimethyltetradecylamine-N-oxide
Dimethyltetradecylamine oxide
N,N-Dimethylmyristamine N-oxide
Tetradecyldimethylamine oxide
Myristamine(dimethyl)amine-N-oxide
MYRISTYL AMINE OXIDE
MYRISTYL AMINE OXIDE Keywords: Myristyl amine oxide, Two-phase titration, Reaction rate, Reaction order, surfactant analysis, Bleaching agents Abstract Myristyl amine oxide is a surface-active agent (surfactant) that has been used in recent years widely in detergent industry as the foaming agent and a viscousing agent. Although this type of surfactants are very stable, however, in some specific chemical media such as strong acid and alkaline cleaners, oxidant media containing sodium hypochlorite may not have sufficient stability. In this study, we will study the effective variables on the decomposition of mirystyl dimethyl amine oxide surfactant with trading name of "Ammonyx" and obtain the rate constant and reaction order of decomposition reaction of the surfactant in specific chemical media for each of these variables and finally the rate law of decomposition. The results of this study show that the decomposition rate of the Ammonyx surfactant to the concentration of NaOH is first-order and the rate constants at three temperatures to 4, 20 and 47 degrees of Celsius are 1.8655×10-4, 2.7548×10-4 and 4.3294×10-4 hr-1 respectively. The Ammonyx surfactants decomposition rate relative to the NaClO concentration is first-order and the rate constant in the three mentioned temperatures is 3.4682×10-4, 4.9251×10-4 and 7.2582×10-4 hr-1 respectively. Please consult your doctor or pharmacist or read the package insert. Cite this page APA Style Citation Myristyl amine oxide / Cyclopentasiloxane - Uses, Side-Effects, Reviews, and Precautions - MLA Style Citation "Myristyl amine oxide / Cyclopentasiloxane - Chicago Style Citation "Myristyl amine oxide / Cyclopentasiloxane - Related Links Myristyl amine oxide / Cyclopentasiloxane for skin conditioning Myristyl amine oxide / Cyclopentasiloxane for hair conditioning More about Myristyl amine oxide / Cyclopentasiloxane Uses Comments Consumer Survey - Myristyl amine oxide / Cyclopentasiloxane The following are the results of an ongoing survey on TabletWise.com for Myristyl amine oxide / Cyclopentasiloxane. These results only show the perceptions of the users of this website. Please make your medical decisions based on the advice of a doctor or a specialist. Uses, Efficiency and Side Effects The following are information on the usage, perceived efficiency and frequency of side effects offered by site visitors for Myristyl amine oxide / Cyclopentasiloxane: Overdose of Myristyl amine oxide / Cyclopentasiloxane Do not use more than prescribed dose. Consuming more of the drug will not improve your symptoms; on the contrary, it can cause poisoning or serious side effects. If you suspect that you or a relative has used an overdose of Myristyl amine oxide / Cyclopentasiloxane, please visit your nearest hospital emergency department. To help doctors, bring necessary information such as a medicine box, bottle, or label. Do not give your medication to someone else, even if you know they have the same condition or they seem to have similar conditions. This can cause an overdose. For more information, consult your pharmacist or check the package insert. Storage of Myristyl amine oxide / Cyclopentasiloxane Store medicines at room temperature, away from heat and light. Do not freeze medicines unless it is written on the package insert. Keep medicines out of the reach of children and pets. Do not pour medicines into the toilet or sink unless you are told to do so in the package insert. Drugs disposed in this way can pollute the nature. Please consult your pharmacist or doctor for more details on how to safely discard Myristyl amine oxide / Cyclopentasiloxane. Expired Myristyl amine oxide / Cyclopentasiloxane Taking a single dose of expired Myristyl amine oxide / Cyclopentasiloxane is likely to cause an adverse event. Consult your family doctor or pharmacist for appropriate advice or if you feel unwell. Expired drugs will not be effective in treating conditions on your prescription. In order to stay safe, it is very important not to use expired medications. If you have a chronic illness that requires constant medication, such as heart disease, seizures, and life-threatening allergies, it is even more important to stay in touch with your GP so that you can replace expired medications immediately. Dosage Information Is this drug or product addictive or addictive? Many drugs are not marketed as addictive or abusive. Often ministries categorize drugs into controlled and non-addictive drugs. For example, this classification is H and X in India and II and V in the USA. Please check the box to make sure the drug belongs to such a special classification. Finally, do not try to self-medicate and increase your body's dependence without the advice of a doctor. Can I stop using this product immediately or do I get rid of it gradually? Some drugs should be tapered or their use should not be stopped suddenly to avoid withdrawal effects. Consult your doctor for recommendations specific to your body and health condition and other medications you can use. Other important information on Myristyl amine oxide / Cyclopentasiloxane Forgetting to take a dose If you forget to take a dose, use it immediately. If your next dose is too close to your time, stop taking the missed dose and stick to your dosing schedule. Do not take extra doses to treat the missed dose. If you regularly forget your doses, set an alarm or ask a family member to remind you. Please consult your doctor to make changes to your dosing schedule or to make up for missed doses if you have recently forgotten too many doses. Before using this medicine, you should inform your doctor about the medicines you are currently using, the medicines you are using without a prescription (e.g. vitamins, herbal supplements, etc.), allergies, your past illnesses and your current health condition (e.g. pregnancy, upcoming surgery, etc.) inform. Certain health conditions can make you more susceptible to the side effects of the medication. Take the steps as directed by your doctor or consider what is written on the product. The dosage depends on your condition. If your condition persists or worsens, notify your doctor. Key issues to consult are listed below. Planning to get pregnant, pregnant or breastfeeding Please consult your doctor or pharmacist or refer to the package insert for this information. Hypersensitivity to Myristyl amine oxide / Cyclopentasiloxane is a contraindication. In addition, Myristyl amine oxide / Cyclopentasiloxane should not be used if you have the following conditions: Hypersensitivity Frequently Asked Questions Is it safe to drive or use heavy machinery while using this product? If you experience side effects such as drowsiness, dizziness, hypotension (low blood pressure) or headache while using Myristyl amine oxide / Cyclopentasiloxane, it may not be safe to drive and / or use a construction machine. If the medication used causes drowsiness, dizziness or lowers your blood pressure, you should not drive. In addition, pharmacists advise patients not to drink alcohol with the drug, as alcohol intensifies side effects such as drowsiness. Please check for these effects on your body when using Myristyl amine oxide / Cyclopentasiloxane. Always consult your doctor for advice specific to your body and health condition. Myristyl amine oxide / Cyclopentasiloxane Medicine Myristyl amine oxide / Cyclopentasiloxane Overview Uses Side effects Precautions Interactions Contraindications Overview Myristyl amine oxide / Cyclopentasiloxane combination is used for Skin conditioning, Hair conditioning and other conditions. Detailed information on the use of Myristyl amine oxide / Cyclopentasiloxane product, side effects, product comments, questions, interactions and precautions are as follows: uses Myristyl amine oxide / Cyclopentasiloxane is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms: Skin conditioning Hair softening Further information: Uses Side effects The following is a list of possible side-effects that may occur in medicines that contain Myristyl amine oxide / Cyclopentasiloxane. This is not an exhaustive list. These side effects are likely to occur, but do not always occur. Some of the side effects are rare but can be very serious. Be sure to consult your doctor if you observe any of the following side effects, especially those that do not go away even if you expect them to. Skin irritation Hives If you notice any side effects other than those listed below, consult your doctor for medical advice. You can also report side effects to your nearest health department official. Measures Limnanthes Alba (Meadowfoam) Seed Oil, Rosa Damascena Flower Water, Beeswax (Cera Alba), Pentylene Glycol, Corylus Avellana (Hazel) Seed Oil, Ormenis Multicaulis Flower Wax, Myristyl amine oxide Carbonate Decahydrate, Limonene, Citrus Medica Lemonum (Lemon) Peel Oil, Osmanthus Fragrans Flower Extract, Anthemis Nobilis Flower Oil, Tocopherol, Citronellol, Geraniol, Citral. If you have oily skin, avoid the first line items in their products being oil. In this case, make sure that the moisturizing agents are glycerin, Myristyl amine oxide, hyaluronic acid or Myristyl amine oxide hyaluronate. Amino acid cocktail: It contains Myristyl amine oxide and 8 types of amino acids found in the skin's own structure. It is very effective in the care of mature skin. It helps the skin to be nourished and restructured. Bifida Ferment Lysate: It is an antiaging active with proven effectiveness. It prevents the damage of UV light on DNA. It helps to repair wrinkles by helping to repair DNA. 50ml Content: Myristyl amine oxide: Protects against dryness by allowing the skin to retain more moisture. It is a natural and important moisturizing agent that is also found in the skin structure. Content: Amino acid cocktail: It contains Myristyl amine oxide and 8 types of amino acids found in the skin's own structure. It is very effective in the care of mature skin. It helps the skin to be nourished and restructured. Glycine Soybean Seed Extract: Increases the strength of the skin with protein, glycoprotein and polysaccharides obtained from soy, renews the skin and revitalizes the skin cells. It helps prevent premature aging effects caused by UV rays and DNA damage on the skin. UVA / UVB Protection Factor: It contains a protection factor of 15 SPF. 50ml Hyaluronic acid, one of the most effective moisture retainers, has a water holding capacity of 1000 times its own weight. It has a tightening effect. It increases the elasticity of the skin. It ensures the transmission of moisture to all cells in the skin. Provides moisturization for a long time on the skin. These products, which plump the skin and provide moisture for a long time, are suitable for day and night use. It also ensures that the skin is smooth and even toned. Active Ingredients / Active Ingredients Myristyl amine oxide, Sodium hyaluronate, Panthenol 10 x 2 ml Myristyl amine oxide Messages Overview(active tab) Safety Resources What Is It? In cosmetics and personal care products, Myristyl amine oxide (pyrrolidonecarboxylic acid) is used mostly in the formulation of hair conditioners and moisturizers. The Myristyl amine oxide salt of Myristyl amine oxide, Myristyl amine oxide, can be found in these products, as well as in shampoos, hair sprays, permanent waves, skin fresheners and other hair and skin care products. Why is it used in cosmetics and personal care products? Myristyl amine oxide and Myristyl amine oxide increase the water content of the top layers of the skin by drawing moisture from the surrounding air. They also enhance the appearance and feel of hair, by increasing hair body, suppleness, or sheen, or by improving the texture of hair that has been damaged physically or by chemical treatment. Abstract Myristyl amine oxide pyrrolidone carboxylic acid is the Myristyl amine oxide salts of 2 pyrrolidone 5 carboxylate, It is one of the major Natural Moisturing factor (NMF) found in human skin. It is documented that Myristyl amine oxide pyrrolidone carboxylic acid (Na- Myristyl amine oxide) is used in hair care & skin care products with great effectivity as it is water extracting skin component. As Na- Myristyl amine oxide is the Natural Moisturizing Agent, it gives suppleness, humectancy & moisturizing property. It is being water soluble, therefore an oil in water (O/W) cream base decided to develop. Three formulae were developed in laboratory incorporating 2.5% & 5% of Na- Myristyl amine oxide &7.5% glycerine. Three cream prepared were further studied for its stability with reference to effect of temp. i.e. at Room Temp.-24-28°c,at oven 50°c, & at refrigerator 90°c, change in colour, odour, pH, globules size & viscosity. It was further decided to study the performance evaluation. Details Myristyl amine oxide stands for Pyrrolidone Carboxylic Acid and though it might not sound like it, it is a thing that can be found naturally in our skin. The Myristyl amine oxide salt form of Myristyl amine oxide is an important skin-identical ingredient and great natural moisturizer that helps the skin to hold onto water and stay nicely hydrated. Description: Myristyl amine oxide is the Myristyl amine oxide salt of pyroglutamic acid which is an uncommon amino acid found naturally in many proteins. Concentration: 50% (dissolved in water). GMO-free, gluten-free. Colorless to pale yellow clear liquid, soluble in water, pH 6.8-7.4. INCI Name: Myristyl amine oxide (sodium L-pyroglutamate) Benefits: Occurs naturally in human skin and is responsible for binding moisture to the cells Highly water-absorbent, holding several time its weight in water, which makes it an excellent humectant Well-know as skin-penetration enhancer Stronger hydrating agent than the traditional compounds like glycerin or propylene glycol Good for hair care as it reduces static electricity. Use: Add as is to the water phase of the formulas, typical use level 1 - 10% in emulsions. For external use only. Applications: All kinds of skin care products such as creams, gels, lotions, hair care products, color cosmetics. Country of Origin: USA Raw material source: The original amino acid proline is obtained mainly from fruits and coconut oil. Manufacture: A fermentation process of sugars and starches is then used in order to create Myristyl amine oxide from proline. Animal Testing: Not animal tested GMO: GMO-free but not certified Vegan: Does not contain any animal-derived components Myristyl amine oxide Myristyl amine oxide is classified as : Antistatic Hair conditioning Humectant Skin conditioning Chem/IUPAC Name: Myristyl amine oxide 5-oxo-2-pyrrolidinecarboxylate Myristyl amine oxide is the Myristyl amine oxide salt of pyroglutamic acid (also known as Myristyl amine oxide). Myristyl amine oxide is a naturally occurring component of human skin and a part of the "natural moisturizing factors" (NMF) that maintain a healthy epidermis. Myristyl amine oxide is very hygroscopic, attracting moisture from the air. It imparts a moist feeling to hair and skin. Myristyl amine oxide applied to the skin is absorbed to a limited extent. It is non-comedogenic, nonirritating to the eye and skin -- even at concentrations up to 50%, and does not contribute to phototoxicity or sensitization. It is rapidly biodegradable. Soluble in water and ethanol and insoluble in oils, it is used for its powerful humectant properties in many skin and hair care products including gels, creams, lotions, shampoos, conditioners, lipsticks and foundations. This Myristyl amine oxide is sourced from all-natural, vegetable-based ingredients; it contains no animal-based ingredients of any kind. INCI: Myristyl amine oxide INCI: Myristyl amine oxide 50% pH-value 6,8-7,4% Dosage: 0,5 - 10% Myristyl amine oxide is a kind of natural moisturizing factor(NMF). It becomes an important additive ingredient in skin-care and hair-care cosmetics in the recent years. It has stronger hydrating power than that of glycerin, sorbitol and propanediol. What is Myristyl amine oxide? Jun 08, 2019 Myristyl amine oxide levels in the skin are highest during childhood. As time progresses, these levels can drop significantly. Using skin care products containing Myristyl amine oxide can help increase these levels as you age. Myristyl amine oxide also contains antioxidants that fight free radicals that can age the skin. It also contains vitamins D and E, which can aid in skin rejuvenation. This powerful moisturizer is made from many herbs, but Myristyl amine oxide from each herb is used to do different things. For example, Myristyl amine oxide from herbs and vegetables can be used as an emollient. When Myristyl amine oxide is derived from coconut oil, it is used as an emulsifier. Myristyl amine oxide found in cherry or seaweed can replenish moisture inside the skin. Myristyl amine oxide can also be used in certain types of lotions that protect the skin from excessive sunlight. This ingredient not only draws moisture into the skin but can also help keep it in. This makes it best suited for all skincare products. When Myristyl amine oxide is used in soaps, it can help the skin in many ways. It works with the natural Myristyl amine oxide found in the skin to create a healthier and renewed skin. Myristyl amine oxide used in shampoos and conditioners helps to retain water in the hair shaft. It can also add shine and bounce to hair. When the hair is very dry, static can build up, causing difficult-to-manage, flying hair. Myristyl amine oxide keeps enough moisture in the hair to eliminate frizzy and dry hair. In small quantities, the use of Myristyl amine oxide is not considered harmful. It is considered to be mildly toxic, but is sometimes used with nitrosamine, which is thought to be a toxin. There were no known skin or eye irritations associated with the use of Myristyl amine oxide. Effects of lactic acid and Myristyl amine oxide pyrrolidone carboxylic acid on the irritated skin reaction induced by Myristyl amine oxide lauryl sulphate patch testing of normal persons and atopic dermatitis patients Background: Natural moisturizing factors such as Myristyl amine oxide pyrrolidone carboxylic acid and lactic acid may play an important role in increasing the moisture retention of isolated stratum corneum and reducing the incidence of dry and flaky skin in vivo. Although the precise mechanism of surfactant irritancy is not fully understood, it has been suggested that barrier dysfunction of stratum corneum by surfactants results in skin changes such as scaling, erythema, and even fissuring. Objective: We evaluated the effect of Myristyl amine oxide pyrrolidone carboxylic acid(Na Myristyl amine oxide) and lactic acid(LA) with several non-invasive measuring methods in the irritated skin reaction induced by Myristyl amine oxide lauryl sulphate (SLS) in normal persons and atopic dermatitis patients. Methods: After skin irritation for 24 hours with patch test of 1% SLS on five volar sites of right forearm, we applied nothing(A), 3% LA+3% Na Myristyl amine oxide PCA(B), 3% LA(C), 3% Na Myristyl amine oxide(D), and vehicle(E) twice a day respectively. Visual score, transepidermal water loss(TEWL), water holding capacity(WHC), and erythema index were measured at 30 min, 24hr, 48hr and 72hr after patch removal. Results: 1. After 72hr, the visual scores of B and C were significantly lower than that of A(control) in atopic dermatitis patients, and that of C in normal persons was significantly lower than that of A, D, and E. 2. TEWL values of B and C in both the normal (after 72hr) and atopic dermatitis group (after 48hr and 72hr) were significantly lower than that of A. 3. WHC values of B, C, D in both the normal and atopic dermatitis group were significantly higher than that of A after 48hr and 72hr. 4. After 72hr, erythema indices by Mexameter® of B, C, and D in both the normal and atopic dermatitis group were significantly lower than that of A and values of C were significantly lower than that of E. In the atopic dermatitis group, values of D were also significantly lower than that of E. 5. The mean visual score was significantly correlated with TEWL value and erythema index of Mexameter (r=0.58, r=0.64) and the TEWL value was significantly correlated with erythema index of Mexameter® (r=0.64). Conclusion: These results suggest that topical application of a moisturizing factor might improve the surfactant-induced disruption of permeability barrier with improvement of the water holding capacity of the stratum corneum. Myristyl amine oxide Pyrrolidone Carboxylic Acid As Moisturizing Agent Abstract: Myristyl amine oxide pyrrolidone carboxylic acid is the Myristyl amine oxide salts of 2 pyrrolidone 5 carboxylate, It is one of the major Natural Moisturing factor (NMF) found in human skin. It is documented that Myristyl amine oxide pyrrolidone carboxylic acid (Na- Myristyl amine oxide) is used in hair care & skin care products with great effectivity as it is water extracting skin component. As Na- Myristyl amine oxide is the Natural Moisturizing Agent, it gives suppleness, humectancy & moisturizing property .It is being water soluble,therefore an oil in water (O/W) cream base decided to develop. Three formulae were developed in laboratory incorporating 2.5% & 5% of Na- Myristyl amine oxide &7.5% glycerine. Three cream prepared were further studied for its stability with reference to effect of temp.i.e. at Room Temp.- 24-280c,at oven 500c, & at refrigerator 900c, change in colour, odour, pH, globules size & viscosity.It was further decided to study the performance evaluation. Key Words: Na- Myristyl amine oxide, NMF, Moisturizing Agent. 1. Introduction: By Kligman, “Moisturizer is defined as a topically applied substance or product that overcomes the signs& symptoms of dry skin”. Idson defined as ,”a Moisturizer,a substance that can favourably affect the feeling of dry skin ,by influencing the water content of stratum corneum” 1 . The approach to restoring water to dry skin has taken three different routes. 1.Occulsion 2.Humectancy 3.Restoration of deficient materials which may be combined. The first approach,occlusion consists in reducing the rate of transepidermal water loss through old or damaged skin or in protecting otherwise healthy skin from the effect of a severely drying environment. The second approach to the moisturizing problem is the use of humectants to attract water from the atmosphere, so supplementing the skin’s water content. The third & perhaps the most valuable approach to moisturization of skin is to determine the precise mechanism of the natural moisturization process to assess what has gone wrong with it in the case of dry skin & to replace any materials in which such research has shown damaged skin to be deficient2 . Moisturizer’s often contain lipids & humectants of low molecular weight, humectants such as urea ,glycerine, lactic acid, pyrrolidone carboxylic acid (Myristyl amine oxide) and salts are absorb into the stratum cornium and their by attracting water, increase hydration3 1.1 Natural Moisturizing Factor(NMF) “A Group of water soluble hydrophilic substances known as the natural moisturizing factor (NMF)4 . Analysis of water soluble component of stratum cornium have indicated the presence of amino –acid lactic acid ,sugar and pyrolidone carboxylic acid.The latter material is found in relatively large concentration in cornified skin.It has recently been shown that salts of this material are extremely ,hygroscopic, dissolving in their own water of hydrations. At pH of stratum corneum (pH5) pyrolidone carboxylic acid exists almost exclusively in the salt form. There result suggest that this material may represent one of the important natural Moisturizing agent for skin5 . Laden and spitzer proved that significant quantities of Na-2-pyrrolidone -5 carboxylate exist in the stratum.This compound is now commercially available for use in cosmetics6 . 1.2 Composition of NMF Amino acids 40% Myristyl amine oxide(Pyrrolidone carboxylic acid) 12% Lactates 12% Urea 7% NH3,Uric acid, glucosamine, creatinine 1.5% Citrates 0.5% Na 5%, k 4%, Ca 1.5 %, Mg 1.5% , Po4 0.5% 18.5 % Sucrore, Organic acid, Peptides, Other aterials 8.5% 1.3 Pyrrolidone Carboxylic Acid(Myristyl amine oxide) ;(C5H7N03) Molecular wt 129.11 7 1.4 Myristyl amine oxide pyrrolidone carboxylic acid (NA- Myristyl amine oxide);(C5H6NNa03) Molecular wt 151.1 8 Na- Myristyl amine oxide is one of the major natural moisturizing factors(NME) found in human skin. It is the Myristyl amine oxide salts of 2 Pyrrolidone-5-Carboxylate(Na- Myristyl amine oxide) is manufactured by dehydration of glutanic acid and forms as odourless solid. Myristyl amine oxide -2 Pyrrolidone-5-Carboxylate has been Patented as a humactant at concentration of 2 % or higher. Water absorption ability of Myristyl amine oxide Pyrrolidone Carboxylate9 Compound %Moisture intake(31%RH) %Moisture intake(58%RH) Pyrrolidone Carboxylic Acid <1 <1 Myristyl amine oxide Pyrrolidone Carboxylic Acid 20 61 Glycerine 13 35 1.5 Uses of Myristyl amine oxide Pyrrolidone Carboxylate in Cosmetics 10 1) Myristyl amine oxide -2-pyrrolidone-5-carboxylate is an important humectants component of NMF. 2) It is used in moisturizing dry flacky skin. 3) It demonstrates excellent hygroscopc & humectants effect & these properties have been achieved with a salt form. 4) Skin & hair care products,suncare,make-up,product are among the major application for Na- Myristyl amine oxide. 5) It moisturizes &protects skin from wind,cold. S.Bhise/Int.J.ChemTech Res.2013,5(4) 1450 2. Materials & Methods Three O/W formulation were developed in laboratory incorporating glycerine & Myristyl amine oxide pyrrolidone carboxylic acid(Na- Myristyl amine oxide). 2.1 Formulation Notation A- Base formulation with 7.5% glycerine. B- Formulation with 2.5% Na- Myristyl amine oxide. C- Formulation with 5.0% Na- Myristyl amine oxide. 2.2 Stability study for Finished Product. All the three samples prepared were subjected to accelerated test conditions & were kept at room temp 24-28 0c,in oven at 50 0c & in refrigerator at 5-8 0c. Stability studies were carried out by accelerated stability test for 40 days. 2.3 Performance Evaluation Ten volunteers were persuaded & then selected. Two cream samples were given to each volunteer one is control i.e. sample- A (7.5% glycerine)& other is sample-C(5% Na- Myristyl amine oxide).Cream was applied twice a day on 3 cm.area of forehand.Sample A on right forehand &sample C on left forehand. sked to see & compaire the effect of sample A & C after two hours upto 30 days. 3. Results & Discussion 1) Result of colour change indicate that at room temp.& at 50 0c the degree of colour change was inversely proportional to the concentration of Myristyl amine oxide, on refrigeration there was no change in colour Summary The medical and biological literature was reviewed with stress laid on the role of pyrrolidone carboxylic acid (Myristyl amine oxide) and its Myristyl amine oxide salt (Na Myristyl amine oxide) in skin, its metabolism, its functions. The paper also includes a summary of 8 years of evaluation work carried out in our Laboratory on creams and lotions containing Myristyl amine oxide-Na Myristyl amine oxide which were assessed by biophysical (impedance measurement, alpha relaxation) and clinical methods. It is now definitely demonstrated that Myristyl amine oxide is an hydrating agent and that all the cosmetic preparations containing at least 2% of the Myristyl amine oxide-Na Myristyl amine oxide salt system improve the condition of dry skin at short or long term provided an adequate vehicle is used (e.g. aqueous solutions are ineffective). The mecanism of action is discussed with reference to metabolism and physiological role of Myristyl amine oxide in stratum corneum. Pyroglutamic acid (also known as Myristyl amine oxide, 5-oxoproline, pidolic acid, or pyroglutamate for its basic form) exists as two distinct enantiomers: (2R) or D and (2S) or L. L-form is a metabolite in the glutathione cycle that is converted to glutamate by 5-oxoprolinase. L-Pyroglutamic acid is produced in the skin through the arginine-citrulline-ornitine-glutamic pathway. The free acid is not hygroscopic; however, the Myristyl amine oxide salts of this acid are more hygroscopic than glycerine. Therefore, formulation of this acid is suggested as a defense against dehydration, for skin conditions involving desquamation. Hydromol Cream (main component of that is Myristyl amine oxide pyrrolidone carboxylate (L form)) is a soft cream which moisturises the skin. Hydromol Cream contains a naturally occurring moisturising agent as well as oils, which prevent moisture loss from the skin. This helps to relieve itch, lubricate and soften the skin. Hydromol Cream is used to treat any condition in which dry skin is a feature such as eczema, ichthyosis (hereditary dry skin) and senile pruritus (itching that may occur in old age). L-Pyroglutamic acid is present in living cells has been reported from archaebacteria to humans, and its occurrence in living cells has been known for over a century. Despite its almost ubiquitous presence, the role of pyroglutamic acid in living cells is poorly understood. Pyroglutamic acid is found as an N-terminal modification in many neuronal peptides and hormones that also include the accumulating peptides in Alzheimer’s disease and familial dementia. The modification is also observed in proteins that include many antibodies, some enzymes and structural proteins. yrrolidone carboxylic acid (Myristyl amine oxide), the primary constituent of the natural moisturizing factor (NMF),1 including its derivatives – such as simple2 and novel3 esters as well as sugar complexes4 – is the subject of great interest and research regarding its capacity to moisturize the stratum corneum via topical application. Creams and lotions containing the Myristyl amine oxide salt of Myristyl amine oxide are widely reported to aid in hydrating the skin and ameliorating dry flaky skin conditions.5,6 In addition, the zinc salt of L-pyrrolidone carboxylate is a longtime cosmetic ingredient due to antimicrobial and astringent qualities. This column briefly addresses the role of Myristyl amine oxide in skin health.7 Dry skin In a comprehensive literature review from 1981, Clar and Fourtanier reported conclusive evidence that Myristyl amine oxide acts as a hydrating agent and that all the cosmetic formulations with a minimum of 2% Myristyl amine oxide and Myristyl amine oxide salt that they tested in their own 8-year study enhanced dry skin in short- and long-term conditions given suitable vehicles (no aqueous solutions).6 In a 2014 clinical study of 64 healthy white women with either normal or cosmetic dry skin, Feng et al. noted that tape stripped samples of stratum corneum revealed significantly lower ratios of free amino acids to protein and Myristyl amine oxide to protein. This was associated with decreased hydration levels compared with normal skin. The investigators concluded that lower NMF levels across the depth of the stratum corneum and reduced cohesivity characterize cosmetic dry skin and that these clinical endpoints merit attention in evaluating the usefulness of treatments for dry skin.8 In 2016, Wei et al. reported on their assessment of the barrier function, hydration, and dryness of the lower leg skin of 25 female patients during the winter and then in the subsequent summer. They found that Myristyl amine oxide levels were significantly greater during the summer, as were keratins. Hydration was also higher during the summer, while transepidermal water loss and visual dryness grades were substantially lower.9 Atopic dermatitis A 2014 clinical study by Brandt et al. in patients with skin prone to developing atopic dermatitis (AD) revealed that a body wash composed of the filaggrin metabolites arginine and Myristyl amine oxide was well tolerated and diminished pruritus. Patients reported liking the product and suggested that it improved their quality of life.10 Later that year, Jung et al. characterized the relationship of Myristyl amine oxide levels, and other factors, with the clinical severity of AD. Specifically, in a study of 73 subjects (21 with mild AD, 21 with moderate to severe AD, 13 with X-linked ichthyosis as a negative control for filaggrin gene mutation, and 18 healthy controls), th
MYRISTYL LACTATE
MYRISTYL LACTATE Myristyl Lactate What Is Myristyl Lactate? Glycolic Acid and Lactic Acid are naturally occuring organic acids also known as Alpha Hydroxy Acids or AHAs. The salts of Glycolic Acid (Ammonium Glycolate, Sodium Glycolate), the salts of Lactic Acid (Ammonium Lactate, Calcium Lactate, Potassiu Lactate, Sodium Lactate, TEA-Lactate) and the esters of Lactic Acid (Methyl Lactate, Ethyl Lactate, Butyl Lactate, Lauryl Lactate, Myristyl Lactate, Cetyl Lactate) may also be used in cosmetics and personal care products. In cosmetics and personal care products, these ingredients are used in the formulation of moisturizers, cleansing products, and other skin care products, as well as in makeup, shampoos, hair dyes and colors and other hair care products. Why is Myristyl Lactate used in cosmetics and personal care products? The following functions have been reported for Glycolic Acid, Lactic Acid and their salts and esters. Buffering agent - Ammonium Lactate, Potassium Lactate, Sodium Lactate Cosmetic astringent - Calcium Lactate Exfoliant - Glycolic Acid, Lactic Acid, Ammonium Glycolate, Ammonium Lactate, Calcium Lactate, Potassium Lactate, Sodium Lactate Humectant - Lactic Acid pH adjuster - Glycolic Acid, Lactic Acid, Ammonium Glycolate, Sodium Glycolate Skin conditioning agent - emollient - Lauryl Lactate, Myristyl Lactate, Cetyl Lactate Skin conditioning agent - humectant - Lactic Acid, Ammonium Lactate, Potassium Lactate, Sodium Lactate, TEA-Lactate Skin conditioning agent - miscellaneous - Lactic Acid Solvent - Methyl Lactate, Ethyl Lactate, Butyl Lactate Scientific Facts: Glycolic Acid and Lactic Acid are alpha hydroxy acids (AHAs). They may be either naturally occurring or synthetic. They are often found in products intended to improve the overall look and feel of the skin. Glycolic acid is the most widely used of out of the group and is usually manufactured from sugar cane. Lactic acid, derived primarily from milk and its origins can be traced back to Cleopatra, who purportedly used sour milk on her skin. MYRISTYL LACTATE MYRISTYL LACTATE is classified as : Emollient Skin conditioning CAS Number 1323-03-1 EINECS/ELINCS No: 215-350-1 COSING REF No: 35457 Chem/IUPAC Name: Tetradecyl lactate Myristyl lactate With its emollient effects (softening) on the skin, it gives skin and hair luster. It is used as base agent in shampoos, lipsticks, and various creams. Cetyl Lactate and Myristyl lactate are the esters of lactic acid and either cetyl or myristyl alcohol. They are used in a wide variety of cosmetic products up to a maximum concentration of 25%. The acute oral lD50 of Cetyl Lactate is estimated from studies with rats to be greater than 20 gfkg. Cetyl Lactate was shown to be minimally irritating to rabbit skin and nonirritating or only slightly irritating to rabbit eyes in Draize irritation tests. At 25%, Cetyl Lactate produced no signs of toxicity or irritation in a 30-day rabbit-skin irritation study. Cetyl lactate was found to be minimally irritating and nonsensitizing to human skin at concentrations up to 5%. The acute oral lD50 of Myristyl lactate is estimated from studies with rats to be greater than 20 g/kg. Myristyl lactate was shown to be minimally irritating in Draize primary skin irritation tests, but one contradictory study concluded that undiluted Myristyl lactate produced moderate irritation. It produced no signs of ocular irritation in Draize rabbit eye irritation tests. Mild irritation was elicited by a formulation in a modified Draize rabbit skin irritation test. The same formulation was found to be nonirritating and nonsensitizing in a human repeated insult patch study. Based on the available information, it is concluded that Cetyl lactate and Myristyl Lactate are safe in the present practices of use. Myristyl Lactate: Myristyl Lactate is the ester produced by a catalyzed reaction of either natural or synthetic myristyl alcohol and lactic acid. The ester produced by the reaction is washed to remove any catalyst and unreacted lactic acid. The final product is further washed with alkali and neutralized. Myristyl Lactate: Myristyl Lactate is a white to yellow liquid or soft solid. Because a hydroxyl group is present, this ingredient is particularly soluble in ethyl alcohol and isopropyl alcohol. It is dispersible in mineral oil and insoluble in water and glycerine.") Measured values for some chemical and physical parameters of Myristyl Lactate are listed below Specific Gravity at 25°C 0.892-0.904 Titer 11 "-1 4°C Saponification Value 166-1 85 Ester Value 166-1 85 Acid Value 3 maximum Iodine Value 1.0 maximum Reactivity Esters undergo nucleophylic substitution. Typical ester reactions include acidic hydrolysis, alkaline hydrolysis, ammonolysis, transesterification, and reduction to alcohols.(’) Analytical Methods Cetyl Lactate and Myristyl Lactate can be positively identified through close matching to standard IR ~pectra.(~,~) A method for thin-layer chromatography identification has also been described.(*) Impurities ’ Cetyl Lactate: Unspecified amounts of myristyl and/or stearyl lactate may be present in commercial Cetyl Lactate. It may also contain a maximum concentration of 0.1 ‘/o ash.(‘) Myristyl lactate: Depending on the purity of the starting materials, unspecified amounts of decyl, lauryl, and/or cetyl lactate may be present in commercial Myristyl Lactate.(4) PURPOSE AND FREQUENCY OF USE IN COSMETICS Cetyl Lactate and Myristyl Lactate are used in cosmetic formulations because of their physical properties. A solid at room temperature, Cetyl Lactate liquifies upon application to the skin. While Myristyl Lactate is a liquid at room temperature, just below this temperature it becomes a soft solid. These lactate esters are nongreasy, nonoily, and nondrying. As they fulfill the functions of lubricant, emollient, and texturizer, they also impart silkiness, sheen, and a degree of water repellancy to the skin and hair. They are extensively used in the production of creamy lipsticks, and at levels of 0.5-2%, they reduce the tackiness of aluminum salt antiperspirant^.'^'^) Neither Cetyl nor Myristyl Lactate reacted in a 52-day period with polystyrene, a material widely used in the packaging of cosmetic products.(10) No evidence was available that suggested any interaction between the Lactates and other ingredients. Cetyl Lactate and Myristyl Lactate are used in a wide variety of product formulations. Product types and the number of formulations reported for each preset concentration range are listed in Table l.(ll) The cosmetic product formulation computer printout which is made available by the Food and Drug Administration (FDA) is compiled through voluntary filing of such data in accordance with Title 21 part 720.4 of the Code of Federal Regulations (1979). Ingredients are listed in prescribed concentration ranges under specific product type categories. Since certain cosmetic ingredients are supplied by the manufacturer at less than 100% concentration, the value reported by the cosmetic formulator may not necessarily reflect the true, effective concentration found in the finished product; the effective concentration in such a case would be a fraction of that reported to the FDA myristyl lactate Molecular FormulaC17H34O3 Average mass286.450 Da Monoisotopic mass286.250793 Da ChemSpider ID58225 Density of myristyl lactate: 0.9±0.1 g/cm3 Boiling Point of myristyl lactate: 330.0±10.0 °C at 760 mmHg Vapour Pressure of myristyl lactate: 0.0±1.6 mmHg at 25°C Enthalpy of Vaporization of myristyl lactate: 66.3±6.0 kJ/mol Flash Point of myristyl lactate: 147.1±7.0 °C Index of Refraction of myristyl lactate: 1.454 Molar Refractivity of myristyl lactate: 84.1±0.3 cm3 #H bond acceptors of myristyl lactate: 3 #H bond donors of myristyl lactate: 1 #Freely Rotating Bonds of myristyl lactate: 15 #Rule of 5 Violations of myristyl lactate: 1 ACD/LogP of myristyl lactate: 6.19 ACD/LogD (pH 5.5) of myristyl lactate: 6.38 ACD/BCF (pH 5.5) of myristyl lactate: 41322.68 ACD/KOC (pH 5.5) of myristyl lactate: 70121.46 ACD/LogD (pH 7.4) of myristyl lactate: 6.38 ACD/BCF (pH 7.4) of myristyl lactate: 41322.59 ACD/KOC (pH 7.4) of myristyl lactate: 70121.30 Polar Surface Area of myristyl lactate: 47 Å2 Polarizability of myristyl lactate: 33.3±0.5 10-24cm3 Surface Tension of myristyl lactate: 33.6±3.0 dyne/cm Molar Volume of myristyl lactate: 310.5±3.0 cm3 Molecular Weight of myristyl lactate: 286.4 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) XLogP3-AA of myristyl lactate: 6.5 Computed by XLogP3 3.0 (PubChem release 2019.06.18) Hydrogen Bond Donor Count of myristyl lactate: 1 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Hydrogen Bond Acceptor Count of myristyl lactate: 3 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Rotatable Bond Count of myristyl lactate: 15 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Exact Mass of myristyl lactate: 286.250795 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Monoisotopic Mass of myristyl lactate: 286.250795 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Topological Polar Surface Area of myristyl lactate: 46.5 Ų Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Heavy Atom Count of myristyl lactate: 20 Computed by PubChem Formal Charge of myristyl lactate: 0 Computed by PubChem Complexity of myristyl lactate: 216 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Isotope Atom Count of myristyl lactate: 0 Computed by PubChem Defined Atom Stereocenter Count of myristyl lactate: 0 Computed by PubChem Undefined Atom Stereocenter Count of myristyl lactate: 1 Computed by PubChem Defined Bond Stereocenter Count of myristyl lactate: 0 Computed by PubChem Undefined Bond Stereocenter Count of myristyl lactate: 0 Computed by PubChem Covalently-Bonded Unit Count of myristyl lactate: 1 Computed by PubChem Compound Is Canonicalized of myristyl lactate: Yes MYRISTYL LACTATE Myristyl Lactate is a lactic acid ester which is mainly used as an emollient in cosmetic products and ensures a smooth skin feeling.
MYRISTYL MYRISTATE
MYRISTYL MYRISTATE MYRISTYL MYRISTATE is classified as : Emollient Opacifying Skin conditioning CAS Number 3234-85-3 EINECS/ELINCS No: 221-787-9 COSING REF No: 35459 Chem/IUPAC Name: Tetradecyl myristate Myristyl Myristate What Is Myristyl Myristate? Myristyl myristate is used in a variety of cosmetics and skincare products to improve the texture of formulations and help to keep the skin moisturized and hydrated. Myristyl myristate is generally used as an emollient, texture enhancer, and co-emulsifier. Myristyl myristate is a naturally derived fatty alcohol. While alcohols are often associated with drying formulations but fatty alcohols are different to other alcohols. Fatty alcohols are a combination of oils and fats with alcohol that actually have hydrating and emollient properties. Myristyl myristate naturally occurs in several types of oils and fats. For instance, nutmeg butter is comprised of 75% trimyristin, the triglyceride of myristic acid. In addition to nutmeg, myristic acid is found in palm kernel oil, coconut oil, butterfat, 8 to 14% of bovine milk, and 8.6% of breast milk. Myristyl myristate exists as a white or yellowish waxy solid. Myristyl myristate is most often made from vegetable oils for cosmetic use. Myristic acid is most commonly used in eye makeup, moisturizers, soaps and detergents, hair care products, nail care products, shaving products, and other skincare products. It is typically used at concentrations of 1 to 10%. THE BREAKDOWN Myristyl Myristate THE GOOD:Myristyl myristate is mainly used to help improve the texture of skincare and cosmetic products but also has the added benefit of helping to moisturize the skin. THE NOT SO GOOD:It is not a particularly active ingredient, apart from adding moisture it does little else for the skin. WHO IS IT FOR?All skin types except those that have an identified allergy to it. SYNERGETIC INGREDIENTS:Works well with most ingredients KEEP AN EYE ON:Nothing to keep an eye on here, myristyl myristate is safe and doesn’t cause irritation. How Does Myristyl Myristate Work? In cosmetics and skincare products, myristyl myristate functions as an emollient, texture enhancer, and moisturizer. Moisture Myristyl myristate is used as a moisturizer in formulations. As an emollient myristyl myristate works to soften and soothe the skin and hair. Emollients work but forming a protective barrier on the surface of the skin. This action helps to trap water in the top few layers of the skin, improving the skin barrier integrity. The skin barrier is the first few layers of the skin and the natural oils that the skin produces that protect the skin from bacteria, allergens, and prevents water loss to the environment. These same properties also help to keep the hair soft, hydrated, and manageable. Myristyl myristate is a soft wax that melts at body temperature, which helps to improve the moisture of the skin and reduce flakiness. Texture Myristyl myristate also functions to improve the texture of formulations. It helps to improve the spreadability of a product, making sure that the product evenly distributes the key ingredients. In certain soap formulations, an excess of myristyl myristate produces pearl effects giving the skin a glossy appearance. Myristyl myristate reduces the watery feel of hand and body lotions and imparts a richness in the sensory feel of the products. Interestingly, the addition of myristyl myristate to an emulsion can take it from dull gray to bright white, making the product look more appealing. Stabilizer Myristyl myristate is also used for its stabilizing benefits. When water and oil-based ingredients are mixed together it is hard to keep them mixed. Myristyl myristate is used to help keep an evenly mixed formulation that prevents separating. The combination of fatty alcohol and fatty acids in myristyl myristate thickens emulsions and improves stability making the emulsion much more stable to temperature variations and higher oil levels. Rather than increasing the amount of emulsifier, which would stiffen the product, a co-emulsifier like myristyl myristate can be used to improve the overall emulsion stability while delivering additional benefits not offered through increased emulsifiers. Is Myristyl Myristate Safe? The safety of myristyl myristate has been assessed by the Cosmetic Ingredient Review Expert Panel. Both animal and human studies have demonstrated that myristyl myristate does not produce skin irritation or sensitization. Based on these findings, the CIR Expert Panel concluded that myristic acid and its salts and esters were safe as a cosmetic ingredient when it’s used for its approved uses and concentrations. Myristyl Myristate What Is Myristyl Myristate? Myristic Acid is a fatty acid that occurs naturally in some foods. Purified Myristic Acid occurs as a hard, white or faintly yellow, glossy crystalline solid, or as a white or yellow-white powder. Salts of Myristic Acid (Aluminum Dimyristate, Aluminum Isostearates/Myristate, Aluminum Myristate, Aluminum Myristates/Palmitates, Calcium Myristate, Magnesium Myristate, Potassium Myristate, Sodium Myristate, Zinc Myristate) and esters of Myristic Acid (Butyl Myristate, Cetyl Myristate, Decyl Myristate, Ethylhexyl Myristate, Ethyl Myristate, Glyceryl Dimyristate, Glyceryl Isostearate/Myristate, Glyceryl Myristate, Isobutyl Myristate, Isocetyl Myristate, Isodecyl Myristate, Isopropyl Myristate, Isostearyl Myristate, Isotridecyl Myristate, Lauryl Myristate, Methyl Myristate, Myristyl Myristate, Octyldodecyl Myristate, Oleyl Myristate, Propylene Glycol Myristate, Tetradecyloctadecyl Myristate, Tridecyl Myristate) may also be used in cosmetics and personal care products. Myristic Acid and its salts and esters may be used in eye makeup, soaps and detergents, hair care products, nail care products, shaving products and other skin care products. Why is Myristyl Myristate used in cosmetics and personal care products? The following functions have been reported for Myristic Acid and its salts and esters. Anticaking agent - Aluminum Dimyristate, Aluminum Isostearates/Myristates, Aluminum Myristate, Aluminum Myristates/Palmitates, Calcium Myristate, Magnesium Myristate, Zinc Myristate Binder - Isopropyl Myristate, Isostearyl Myristate, Tetradecyloctyldecyl Myristate Emulsion stabilizer - Aluminum Dimyristate, Aluminum Isostearates/Myristates, Aluminum Myristate, Aluminum Myristates/Palmitates, Calcium Myristate, Tetradecyloctyldecyl Myristate Film former - Tetradecyloctyldecyl Myristate Hair conditioning agent - Ethyl Myristate, Isotridecyl Myristate, Lauryl Myristate, Oleyl Myristate Opacifying agent - Myristic Acid, Tetradecyloctyldecyl Myristate Slip modifier - Magnesium Myristate, Zinc Myristate Skin-Conditioning Agent - Emollient - Butyl Myristate, Ethylhexyl Myristate, Ethyl Myristate, Glyceryl Dimyristate, Glyceryl Isostearate/Myristate, Glyceryl Myristate, Isobutyl Myristate, Isodecyl Myristate, Isopropyl Myristate, Isostearyl Myristate, Methyl Myristate, Propylene Glycol Myristate Skin-conditioning agent - occlusive - Cetyl Myristate, Decyl Myristate, Isocetyl Myristate, Isotridecyl Myristate, Lauryl Myristate, Myristyl Myristate, Octyldodecyl Myristate, Oleyl Myristate, Tetradecyloctyldecyl Myristate, Tridecyl Myristate Surfactant - cleansing agent - Myristic Acid, Potassium Myristate, Sodium Myristate Surfactant - emulsifying agent - Potassium Myristate, Sodium Myristate, Glyceryl Isostearate/Myristate, Glyceryl Myristate, Propylene Glycol Myristate Viscosity increasing agent - nonaqueous - Aluminum Dimyristate, Aluminum Isostearates/Myristates, Aluminum Myristate, Aluminum Myristates/Palmitates, Calcium Myristate, Magnesium Myristate, Zinc Myristate Scientific Facts: Myristic Acid, also called tetradecanoic acid, occurs naturally in vegetable or animal fats and oils with relatively high levels found in nutmeg, palm oil, coconut oil and butter fat. The salts of Myristic acid are formed by reaction with base materials such as sodium or potassium hydroxide. The esters of Myristic Acid are derived from Myristic Acid and an alcohol. For example, Isopropyl Myristate is derived from Myristic Acid and isopropyl alcohol, and Butyl Myristate is derived from Myristic Acid and butyl alcohol. Details Myristyl Myristate's a waxy emollient with a melting point near to skin temperature. It gives body and consistency to the formula and leaves a velvety feel on the skin. Myristyl Myristate has a high comedogenicity index (5 out of 5), so it might clog pores if you are prone to it. Famous dermatologist, Dr. Leslie Baumann also writes in her book, The Skin Type Solution to avoid this ingredient if you are acne-prone. Tetradecyl tetradecanoate is a tetradecanoate ester (myristate ester) resulting from the formal condensation of the carboxy group of tetradecanoic acid (myristic acid) with the hydroxy group of tetradecan-1-ol (myristyl alcohol). Used as an emollient. It has a role as an algal metabolite. It is a wax ester and a tetradecanoate ester. It derives from a tetradecan-1-ol. Molecular Weight of Myristyl Myristate: 424.7 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) XLogP3-AA of Myristyl Myristate: 13 Computed by XLogP3 3.0 (PubChem release 2019.06.18) Hydrogen Bond Donor Count of Myristyl Myristate: 0 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Hydrogen Bond Acceptor Count of Myristyl Myristate: 2 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Rotatable Bond Count of Myristyl Myristate: 26 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Exact Mass of Myristyl Myristate: 424.428031 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Monoisotopic Mass of Myristyl Myristate: 424.428031 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Topological Polar Surface Area of Myristyl Myristate: 26.3 Ų Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Heavy Atom Count of Myristyl Myristate: 30 Computed by PubChem Formal Charge of Myristyl Myristate: 0 Computed by PubChem Complexity of Myristyl Myristate: 327 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Isotope Atom Count of Myristyl Myristate: 0 Computed by PubChem Defined Atom Stereocenter Count of Myristyl Myristate: 0 Computed by PubChem Undefined Atom Stereocenter Count of Myristyl Myristate: 0 Computed by PubChem Defined Bond Stereocenter Count of Myristyl Myristate: 0 Computed by PubChem Undefined Bond Stereocenter Count of Myristyl Myristate: 0 Computed by PubChem Covalently-Bonded Unit Count of Myristyl Myristate: 1 Computed by PubChem Compound of Myristyl Myristate Is Canonicalized Yes Myristyl Myristate is a 100% natural vegetable derived ester utilizing only the Myristic fatty acids. This combination of myristyl alcohol and myristic acid results in superior whitening to the product and improved benefits to the skin. Myristyl Myristate is used as a co-emulsifier for it's emulsion stabilizing benefits. The combination of fatty alcohol and fatty acids thickens emulsions and improves stability making the emulsion much more stable to temperature variations and higher oil and butter levels. The perfect choice when you've created your emulsion and it's just on the verge of de-stabilizing. This will be apparent through an appearance of oil or air in your product. Rather than increasing your emulsifier which would also stiffen your product, in most cases, a co-emulsifier is used to improve the overall emulsion stability while delivering additional benefits not offered through increased emulsifiers. Myristyl Myristate is also used to improve the aesthetics of emulsions. This is a good choice when your emulsion has an unpleasant color or dullness. Just the addition of Myristyl Myristate can take your emulsion from grey to bright white while giving it a smooth glossy appearance. Myristyl Myristate is most commonly used to improve the performance of emulsions. Being base on fatty acids it delivers skin conditioning benefits and improved moisture retention. Myristyl Myristate will also impart a very pleasant soft powdery feel on the skin. This is a great addition to your formulas when your final product does not deliver a nice feel on the skin or leaves the skin feeling too greasy. By adding Myristyl Myristate you can keep your oil and butter levels higher and still avoid the unpleasant greasiness. Myristyl Myristate offers an easy way to create lotions and creams with a silky, rich feel and a dry powdery feel. Especially suitable for those products with a high butter content when the oily effect is undesirable. Functioning as both a co-emulsifier and an opacifier it's an easy way to improve the visual appeal of your product while at the same time improving on the feel of the product on the skin. ATTRIBUTES Provides a pleasantly soft & substantive feel to emulsions Offers an excellent dry powdery feel on the skin Contributes excellent emulsion enhancement, imparting body and a white opacifying effect Offers a solution to natural color where it gives your emulsions white glossy appearance Excellent super fatting / thickening agent GUIDELINES 2.0 - 8.0% Add to the oil phase APPLICATIONS Creams and Lotions Massage and Body Oils Hair Conditioners SPECIFICATIONS Appearance: White Flake Odor: Characteristic Solubility: Oil Storage: Cool, Tightly Sealed, Protected from Moisture Shelf: 24 Months Properly Stored / Handled myristyl myristate Rating: GOOD Categories: Texture Enhancer, Emollients Used in cosmetics as a texture enhancer and emollient. It has a wetter feel and is best for dry skin. Functions: Myristyl Myristate is a naturally derived ester, formed by the combination of Myristyl Alcohol and Myristic Acid, which occurs naturally in animal or vegetable fats or oils. It is originally formed as a white or yellowish waxy solid, and is used as a skin conditioning agent, emulsifier and opacifier in skin care products and cosmetics. It provides a pleasant, soft feel to formulas, as well as an excellent dry, powdery after-feel to lotions and creams, according to research. Myristyl Myristate is an excellent emulsion enhancer that imparts a white opacifying effect or glossy appearance, and is an effective thickening agent as well. Safety Measures/Side Effects: Myristyl Myristate is considered safe and is approved by the CIR for use in cosmetics. The EWG reports a 95% safety rating for it, although some studies have linked it to mild irritation when applied to skin directly.
N BUTANOL
N butanol has limited miscibility in water; however, it is easily soluble in regular solvents such as ethers, alcohol, glycols and hydrocarbons.
N butanol is a colourless liquid that has a very characteristic strong odour.
N butanol’s also known as Butyl Alcohol.

CAS Number: 71-36-3
Molecular Formula: C4H10O
Molecular Weight: 74.12
EINECS Number: 200-751-6

N butanol manufacturing process is quite complex, especially when it comes to health risks.
N butanol is found in its natural state, a product of fermentations of some foods and fruits that contain sugars.
N butanol, also known as normal butanol or n-butyl alcohol, is a type of alcohol with the chemical formula C4H9OH.

N butanol is one of the four isomers of butanol, with the other three being isobutanol, sec-butanol, and tert-butanol.
The "n" in N butanol stands for "normal," indicating that its carbon chain is linear.
N butanol is a colorless liquid with a strong alcoholic odor.

N butanol is soluble in water and commonly used as a solvent in various industrial applications, including paints, coatings, and chemical processes.
N butanol can also be found in some consumer products such as cleaning agents, perfumes, and personal care products.
Additionally, N butanol is used as a fuel additive and in the production of plastics, resins, and pharmaceuticals.

This solvent is very flammable, with a flashpoint of around 35° C.
N butanol produced in small amounts in humans by the gut microbes.
N butanol has a role as a protic solvent, a human metabolite and a mouse metabolite.

N butanol is a clear, mobile solvent with a characteristic odour similar to banana.
N butanol is flammable and has medium volatility.
N butanol is a type of alcohol with four carbon atoms being contained per molecule.

N butanol molecular formula is CH3CH2CH2CH2OH with three isomers, namely iso-butanol, sec-butanol and tert-butanol.
N butanol is colorless liquid with alcohol odor.
N butanol has the boiling point of being 117.7 ℃, the density (20 ℃) being ​​0.8109g/cm3, the freezing point being-89.0 ℃, flash point being 36~38 ℃, self-ignition point being 689F and the refractive index being (n20D) 1.3993.

At 20 ℃, its solubility in water is 7.7% (by weight) while the water solubility in N butanol was 20.1% (by weight).
N butanol is miscible with ethanol, ether and other kinds of organic solvents.
N butanol is miscible with common solvents such as alcohols, ketones, aldehydes, ethers, glycols and aromatic and aliphatic hydrocarbons but has only limited miscibility in water.

N butanol is a primary alcohol with a molecular formula of C4H10O.
N butanol is a primary alcohol that is butane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group.
N butanol can be used as the solvents of a variety of paints and the raw material for producing the plasticizers, dibutyl phthalate.

N butanol is a four-carbon alcohol with a linear carbon chain, which means it has a straight-chain structure.
N butanol is a colorless liquid at room temperature with a boiling point of about 117.7 degrees Celsius (243.9 degrees Fahrenheit).
N butanol has a slightly sweet odor, similar to that of other alcohols.

N butanol is soluble in water to some extent, which makes it useful as a solvent.
However, it is less soluble in water compared to its isomers like ethanol or methanol.
N butanol is a clear, mobile, neutral liquid with a characteristic odour.

N butanol is miscible with all common solvents, e. g. alcohols, ketones, aldehydes, ethers, glycols, and aromatic and aliphatic hydrocarbons.
N butanol miscibility with water, however, is restricted. N butanol is used as a solvent and as a feedstock for syntheses.
A survey of the various applications is presented below, but does not claim to be complete.

About half of the production of pure N butanol and its derivates (primarily esters) is used as solvents in the coatings industry.
The advantage here is that N butanol prevents blushing of certain coatings when they dry under humid conditions.
Thus it is widely used as a diluent in cellulose nitrate lacquers and serves to improve their flow, gloss and resistance to blushing (blushing only occurs in the presence of volatile solvents and at high humidities).

For this purpose addition rates of 5-10 % are generally sufficient.
N butanol, also known as butan-1-ol or N butanol, is a primary alcohol with the chemical formula C4H9OH and a linear structure.
N butanol can also be used for the manufacture of butyl acrylate, butyl acetate, and ethylene glycol butyl ether and also used as the extract of intermediates of organic synthesis and biochemical drugs and can also used in the manufacture of surfactants.

N butanol steam can form explosive mixtures with air with the explosion limit being 3.7%~10.2% (volume fraction).
N butanol was first discovered by C-A. Wurtz (French) from the fusel oil obtained from the fermentation process of alcohol in 1852.
In 1913, the British Strange-Graham Companies have used corn as raw material for production of acetone through the fermentation process with butanol being the main byproduct.

Later, due to the increasing demand for butanol, the fermentation production factory began to mainly synthesize N butanol with acetone and ethanol being the major byproduct.
N butanol is a colourless liquid of medium volatility and a characteristic banana-like odour.
N butanol is a primary alcohol, a short-chain primary fatty alcohol and an alkyl alcohol.

During the Second World War, the German chemical company (Ruhr) began to apply propylene carboxyl method for the production of N butanol.
With the rise of the oil industry in 1950s, the N butanol synthesis method had gotten rapid development with the propylene carboxyl method having the fastest speed.

N butanol is classed as a flammable liquid with a flammability rating of 3 under the NDPA 704 due to its flashpoint of 35 °C.
A bulk solvent exporter, such as Solventis, would normally distribute this solvent in bulk vessels or tank trucks.
N butanol can occur naturally as a product of the fermentation of sugars and other carbohydrates.

However, the major use (and therefore production) is in the industrial arena.
N butanol is a bulk petrochemical manufactured from the feedstock of propylene in an ‘oxo process’ in the presence of a homogeneous catalyst.
This creates butyraldehyde which is subsequently hydrogenated to produce N butanol.

N butanol occurs naturally as a minor product of the ethanol fermentation of sugars and other saccharides and is present in many foods and drinks.
N butanol is also a permitted artificial flavorant in the United States, used in butter, cream, fruit, rum, whiskey, ice cream and ices, candy, baked goods, and cordials.
N butanol is also used in a wide range of consumer products.

The largest use of N butanol is as an industrial intermediate, particularly for the manufacture of butyl acetate (itself an artificial flavorant and industrial solvent).
N butanol is a petrochemical derived from propylene.
Estimated production figures for 1997 are: United States 784,000 tonnes; Western Europe 575,000 tonnes; Japan 225,000 tonnes.

N butanol alcohol is a colourless flammable liquid with strong alcoholic odour.
N butanol alcohol is a highly refractive liquid and burns with a strongly luminous flame.

N butanol is incompatible with strong acids, strong oxidising agents, aluminium, acid chlorides, acid anhydrides, copper, and copper alloys.
N butanol alcohol has an extensive use in a large number of industries.
For instance, it is used as solvent in industries associated with the manufacturing of paints, varnishes, synthetic resins, gums, pharmaceuticals, vegetable oils, dyes, and alkaloids.

N butanol alcohol finds its use in the manufacture of artificial leather, rubber, plastic cements, shellac, raincoats, perfumes, and photographic films.
N butanol is a colorless flammable liquid with a strong alcoholic odor.
N butanol is a highly refractive liquid and burns with a strongly luminous flame.

N butanol is incompatible with strong acids, strong oxidizing agents, aluminium, acid chlorides, acid anhydrides, copper, and copper alloys.
N butanol has extensive use in a large number of industries.
For instance, N butanol is used as a solvent in industries associated with the manufacturing of paints, varnishes, synthetic resins, gums, pharmaceuticals, vegetable oils, dyes, and alkaloids.

N butanol is used in the manufacture of artificial leather, rubber, and plastic cements, shellac, raincoats, perfumes, and photographic films.
N butanol is a solvent, chemical intermediate and an additive in unleaded gasoline.
N butanol is a colorless, volatile liquid with a rancid sweet odor.

The air odor threshold of N butanol was reported to be 0.83 ppm ; others have identified the minimum concentration with identifiable odor as 11 and 15 ppm.
N butanol can also be added to diesel fuel to reduce soot emissions.
The production of, or in some cases, the use of, the following substances may result in exposure to N butanol: artificial leather, butyl esters, rubber cement, dyes, fruit essences, lacquers, motion picture, and photographic films, raincoats, perfumes, pyroxylin plastics, rayon, safety glass, shellac varnish, and waterproofed cloth.

N butanol occurs naturally as a result of carbohydrate fermentation in a number of alcoholic beverages, including beer, grape brandies, wine, and whisky.
N butanol has been detected in the volatiles of hops, jack fruit, heat-treated milks, musk melon, cheese, southern pea seed, and cooked rice.

N butanol is also formed during deep frying of corn oil, cottonseed oil, trilinolein, and triolein.
N butanol is one of the "fusel alcohols" (from the German for "bad liquor"), which include alcohols that have more than two carbon atoms and have significant solubility in water.
N butanol is a natural component of many alcoholic beverages, albeit in low and variable concentrations.

N butanol (along with similar fusel alcohols) is reputed to be responsible for severe hangovers, although experiments in animal models show no evidence for this.
N butanol is used as an ingredient in processed and artificial flavorings, and for the extraction of lipid-free protein from egg yolk, natural flavouring materials and vegetable oils, the manufacture of hop extract for beermaking, and as a solvent in removing pigments from moist curd leaf protein concentrate.

N butanol is a primary alcohol that is butane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group.
N butanol is produced in small amounts in humans by the gut microbes.
N butanol has a role as a protic solvent, a human metabolite and a mouse metabolite.

N butanol is a primary alcohol and an alkyl alcohol.
N butanol is clear, colorless liquid with a rancid sweet odor similar to fusel oil.
The least detectable odor threshold in concentration water at 60 °C was 0.2 mg/L.

Reported nasal pungency threshold concentrations ranging from approximately 900 to 4,000 ppm.
N butanol also known as N butanol is a primary alcohol with the chemical formula C4H9OH and a linear structure.
Isomers of N butanol are isobutanol, 2-butanol, and tert-butanol.

The unmodified term butanol usually refers to the straight chain isomer.
N butanol is a colourless flammable liquid with strong alcoholic odour.
N butanol is a highly refractive liquid and burns with a strongly luminous flame.

N butanol is incompatible with strong acids, strong oxidising agents, aluminium, acid chlorides, acid anhydrides, copper, and copper alloys.
N butanol has an extensive use in a large number of industries. For instance, it is used as solvent in industries associated with the manufacturing of paints, varnishes, synthetic resins, gums, pharmaceuticals, vegetable oils, dyes, and alkaloids.

N butanol finds its use in the manufacture of artificial leather, rubber, plastic cements, shellac, raincoats, perfumes, and photographic films.
N butanol occurs naturally as a minor product of the fermentation of sugars and other carbohydrates and is present in many foods and beverages.
N butanol is also a permitted artificial flavorant in the United States, used in butter, cream, fruit, rum, whiskey, ice cream and ices, candy, baked goods, and cordials.
N butanol is also used in a wide range of consumer products.

N butanol is a natural product found in Vitis rotundifolia, Cichorium endivia, peppermint oil from Brazil, Achillea ageratum, tea, apple aroma, American cranberry, black currants, guava fruit, papaya, cooked asparagus, tomato, Swiss cheese, Parmesan cheese, heated butter, cognac, Armagnac, rum and cider.
N butanol has been proposed as a substitute for diesel fuel and gasoline.
N butanol is produced in small quantities in nearly all fermentations (see fusel oil).

N butanol has the same use as the rest of its chemical group.
Alcohols work as an intermediary for chemical reactions in industry, being used as a solvent and dehydrating agent.

Melting point: -90 °C (lit.)
Boiling point: 116-118 °C (lit.)
Density: 0.81 g/mL at 25 °C (lit.)
vapor density: 2.55 (vs air)
vapor pressure: 6.7 hPa (20 °C)
FEMA: 2178 | BUTYL ALCOHOL
refractive index: n20/D 1.399(lit.)
Flash point: 95 °F
storage temp.: Store at +5°C to +30°C.
solubility: water: soluble
form: Liquid
pka: 15.24±0.10(Predicted)
color: APHA: ≤10
Relative polarity: 0.586
PH: 7 (70g/l, H2O, 20℃)
Odor: Alcohol-like; pungent; strong; characteristic; mildly alcoholic, non residual.
Odor Threshold: 0.038ppm
Odor Type: fermented
Evaporation Rate: 0.46
Relative density, gas (air=1): 0.81
explosive limit: 1.4-11.3%(V)
Water Solubility: 80 g/L (20 ºC)
Sensitive: Moisture Sensitive
λmax λ: 215 nm Amax: 1.00
λ: 220 nm Amax: 0.50
λ: 240 nm Amax: 0.10
λ: 260 nm Amax: 0.04
λ: 280-400 nm Amax: 0.01
LogP: 0.88

N butanol may form explosive mixture with air.
N butanol can be produced through various methods, including the oxo process (also known as the hydroformylation of propene) and the hydroformylation of propionaldehyde.
As mentioned earlier, N butanol is one of four isomers of butanol.

The other isomers have different structures and properties.
N butanol, for instance, has a branched structure and is used in the production of chemicals like isobutyl acetate, while tert-butanol is used as a solvent and in the synthesis of pharmaceuticals.
N butanol is sometimes used as an octane booster in gasoline.

By adding N butanol to gasoline, the octane rating of the fuel can be increased.
A higher octane rating can reduce engine knocking and improve overall engine performance.
N butanol is used in the flavor and fragrance industry to enhance the aroma of certain products.

In all cases they are Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions.
Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.
Attacks some plastics, rubber and coatings.

N butanol is incompatible with strong acids; halogens, caustics, alkali metals; aliphatic amines; isocyanates.
N butanol forms an explosive peroxide in air.
Incompatible with strong oxidizers; strong acids; aliphatic amines; isocyanates, organic peroxides.

N butanol is incompatible with strong acids (including mineral acid), including mineral acids; strong oxidizers or caustics, aliphatic amines; isocyanates, alkali metals (i.e., lithium, sodium, potassium, rubidium, cesium, francium).
N butanol is incompatible with strong acids; strong oxidizers; caustics, aliphatic amines; isocyanates, alkali metals and alkali earth.
N butanol are used as solvents for paints, lacquers, varnishes, natural and synthetic resins, gums, vegetable oils, dyes, camphor, and alkaloids.

They are also used as an intermediate in the manufacture of pharmaceuticals and chemicals; in the manufacture of artificial leather, safety glass; rubber and plastic cements, shellac, raincoats, photographic films, perfumes; and in plastic fabrication.
The acute toxicity of N butanol is relatively low, with oral LD50 values of 790–4,360 mg/kg (rat; comparable values for ethanol are 7,000–15,000 mg/kg).
N butanol is metabolized completely in vertebrates in a manner similar to ethanol: alcohol dehydrogenase converts N butanol to butyraldehyde; this is then converted to butyric acid by aldehyde dehydrogenase.

N butanol can be found in perfumes, colognes, and various scented products.
N butanol is utilized in the pharmaceutical industry for various purposes.
N butanol can be used as a solvent in the synthesis of pharmaceutical compounds, and it may also be found as an excipient in some medications.

N butanol can be found in cleaning products like household cleaners, degreasers, and industrial solvents due to its strong solvent properties, which help in breaking down and removing oils, greases, and other residues.
N butanol is used in the manufacture of plastics and resins, including acrylate resins and cellulose acetate butyrate, where it serves as a plasticizer or modifier to improve flexibility and other properties.
N butanol can be produced through fermentation processes using certain microorganisms, making it a potential candidate for biofuel production.

N butanol has been considered as a biofuel alternative due to its energy density and compatibility with existing engines and infrastructure.
In the chemical and pharmaceutical industries, N butanol is used for extraction and purification processes.
N butanol can be employed to separate and purify various compounds from mixtures.

While N butanol itself is not typically used as a food additive, it can be present as a residue in trace amounts in some food products due to its use as a solvent or in food packaging materials.
Regulatory authorities set limits on the permissible levels of such residues to ensure food safety.
The production and use of N butanol can have environmental impacts.

Efforts have been made to develop more environmentally friendly and sustainable methods for its production, such as bio-based processes.
N butanol attacks plastics.
Mixtures with concentrated sulfuric acid and strong hydrogen peroxide can cause explosions.

May form explosive butyl hypochlorite by reacting with hypochlorous acid.
N butanol can be fully metabolized to carbon dioxide and water by the β-oxidation pathway.

In the rat, only 0.03% of an oral dose of 2,000 mg/kg was excreted in the urine.
At sub-lethal doses, N butanol acts as a depressant of the central nervous system, similar to ethanol: one study in rats indicated that the intoxicating potency of N butanol is about 6 times higher than that of ethanol, possibly because of its slower transformation by alcohol dehydrogenase.

Production method:
There are several methods for their preparation.
In the past, the production of N butanol has also used potatoes, grain or sugar as raw material and through their hydrolysis fermentation.

The resulting product from the fermentation broth contains a N butanol content of 54.8%~58.5%, acetone content of 30.9%~33.7%, and the ethanol content of 7.8%-14.2%. With the development of petrochemical industry, fermentation method has been gradually phased out.
The reaction equation is as follows: (C6H10O5) n [n (H2O)] → [strain] n-C6H12O6 [fermentation] → CH3COCH3 + C4H9OH + C2H5OH
The resulted fermentation broth was further fractionated to obtain acetone, ethanol and N butanol separately.

Take acetaldehyde as raw material, add dilute alkali solution to give 2-hydroxybutyraldehyde at temperature below 20 ℃ with the reaction being stopped upon reaching 50%.
N butanol use alkali to neutralize the acid and recycle the unreacted acetaldehyde and extract the 2-hydroxybutyraldehyde.
Then use acidic catalyst such as sulfuric acid and acetic acid for dehydration to obtain crotonaldehyde at 105~137 ℃, then use copper complex catalyst for hydrogenation at 160~240 ℃ to obtain the crude butyraldehyde and N butanol with distillation to obtain the products.

CH3CH = CHCHO + H2 [catalyst] CH3CH2CH2CHO + CH3CH2CH2CH2OH
N butanols synthesis method including the following several ways: Fermentation and Propylene carbonyl synthesis.
Put propylene, carbon monoxide and hydrogen to the catalytic bed for reaction with catalyst being zeolite for absorbing cobalt salt or fatty acid cobalt with the reaction temperature being 130~160 ℃ and the reaction pressure being 20~25MPa.

The reaction can generate n-butyraldehyde and iso-butyraldehyde with separation via distillation and further catalytic hydrogenation of the n-butyraldehyde to obtain the N butanol.
CH3CH2CH2CHO + H2 → CH3CH2CH2CH2OH
N butanol applies the mixture of iron pentacarbonyl, n-butyl pyrrolidine and water.

However, the one-way conversion of the propylene is low with only 8% to 10%.
Reaction equation: CH3CH = CH2 + 3CO + 2H2O → n-C4H9OH + 2CO2

Uses:
N butanol is used in the following products: coating products, washing & cleaning products, lubricants and greases, laboratory chemicals, adhesives and sealants and metal working fluids.
N butanol is used in the following products: coating products, washing & cleaning products, lubricants and greases, metal working fluids, laboratory chemicals and fillers, putties, plasters, modelling clay.

N butanol has an industrial use resulting in manufacture of another substance (use of intermediates).
N butanol is used for the manufacture of: chemicals.
Release to the environment of N butanol can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and of substances in closed systems with minimal release.

Release to the environment of N butanol can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and formulation of mixtures.
N butanol is used in the following areas: building & construction work, scientific research and development, printing and recorded media reproduction and health services.
N butanol is used for the manufacture of: plastic products, mineral products (e.g. plasters, cement) and furniture.

Other release to the environment of N butanol is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
N butanol is used in the following products: coating products, fillers, putties, plasters, modelling clay and inks and toners.
Release to the environment of N butanol can occur from industrial use: formulation of mixtures and manufacturing of the substance.

N butanol is the most important in industries and the most extensively studied.
N butanol is a colorless liquid with a strong, mildly alcoholic odor.

N butanol is used in chemical derivatives and as a solvent for paints, waxes, brake fluid, and cleaners.
N butanol is the allowable food flavors documented in the "food additives health standards" of China.
N butanol is mainly used for the preparation of food flavors of bananas, butter, cheese and whiskey.

For the candy, the usage amount should be 34mg/kg; for baked foods, it should be 32mg/kg; for soft drinks, it should be 12mg/kg; for cold drinks, it should be 7.0mg/kg; for the cream, it should be 4.0mg/kg; for alcohol, it should be 1.0mg/kg.
N butanol is mainly used for the manufacture of the n-butyl plasticizers of phthalic acid, aliphatic dicarboxylic acid and phosphoric acid that are widely applied to various kinds of plastic and rubber products.
N butanol can also be used as the raw material of producing butyraldehyde, butyric acid, butyl-amine and butyl lactate in the field of organic synthesis.

N butanol can also be used as the extraction agent of oil, drugs (such as antibiotics, hormones and vitamins) and spices as well as the alkyd paint additives.
N butanol can be used as the solvent of organic dyes and printing ink and de-waxing agent.
N butanol is used in the production of butylacetate, butyl glycol ether, and plasticizerssuch as dibutyl phthalate; as a solvent in thecoating industry; as a solvent for extractionsof oils, drugs, and cosmetic nail products;and as an ingredient for perfumes and flavor.

N butanol can be used as a chemical intermediate to create other chemicals (e.g., esters, n-butyl acetate, and amino resins); alternatively, it can be used as a solvent in the creation of consumer products.
N butanol is used as a solvent for paints, coatings, varnishes, fats, oils, waxes, rubber, and plasticizers.

Other uses include coating fabric in the textiles industry, as a cleaning or polishing agent, gasoline, brake fluid and in consumer products such as make-up, nail products, hygiene products and shaving products in the cosmetic industry.
N butanol is primarily used as a solvent in various industries, including the manufacturing of paints, coatings, varnishes, and inks.
N butanol is appreciated for its ability to dissolve a wide range of substances.

N butanol serves as a precursor in the synthesis of various chemicals, including esters, butyl acrylate, and plasticizers.
In some cases, N butanol is used as an additive in gasoline to improve its octane rating and reduce emissions.
N Butanol is used as a solvent, as an ingredient in various formulations such as cosmetics and as a starting material to produce other chemicals.

N Butanol is primarily used in the coatings industry where it is widely used as a diluent in cellulose nitrate lacquers as it improves their flow, gloss and resistance to blushing.
N butanol is suitable for use as a solvent for acid-curable lacquers and baking finishes derived from urea, melamine, or phenolic resins, where it is mainly used together with glycol ethers or ethanol.
N butanol is employed as a solvent for paints, lacquers & varnishes, natural & synthetic resins, gums, vegetable oils, dyes & alkaloids.

N butanol is used as an intermediate in the manufacture of pharmaceuticals & chemicals, & employed in industries producing artificial leather, textiles, safety glass, rubber cement, shellac, raincoats, photographic films & perfumes.
N butanol is used primarily as an industrial intermediate in the production of ethers and butyl ether acetates, pharmaceuticals, polymers and plastics.
N butanol is used to a lesser extent as a solvent, reactant/diluent and component in consumer (nail polishn formulations, rubber cement and safety glass) and industrial products.

In some cases, N butanol is added to gasoline as an octane booster.
N butanol can improve the octane rating of gasoline, which can lead to better engine performance and reduced knocking.
N butanol is used to enhance the aroma of certain perfumes, colognes, and scented products.

N butanol is used in the production of household and industrial cleaners and degreasers due to its effective solvent properties.
N butanol is used in the production of plastics and resins, such as acrylate resins and cellulose acetate butyrate, where it functions as a plasticizer or modifier to improve flexibility and other properties.
N butanol can be produced through fermentation processes using certain microorganisms, making it a potential candidate for biofuel production.

N butanol has been considered as a biofuel alternative due to its energy density and compatibility with existing engines and infrastructure.
N butanol at 85% can be used in car engines that are designed for gasoline with no engine modification required.
This allows for lower fuel consumption than other gasoline alternatives such as ethanol due to the lower oxygen content of N butanol.

The chemical is present in several foods and beverages as an artificial flavouring.
N butanol is also used in food preparation such as during the manufacture of hop extract for beermaking.
Release to the environment of N butanol can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release.

Other release to the environment of N butanol is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).
N butanol can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery) and plastic (e.g. food packaging and storage, toys, mobile phones).

N butanol occurs in fusel oil and as aby-product of the fermentation of alcoholicbeverages such as beer or wine.
It is presentin beef fat, chicken broth, and nonfilteredcigarette smoke
N butanol is used in the following products: lubricants and greases, coating products, anti-freeze products, adhesives and sealants, polishes and waxes, finger paints, washing & cleaning products, inks and toners, leather treatment products and non-metal-surface treatment products.

Other release to the environment of N butanol is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids) and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).
N butanol is widely used as a solvent in the formulation of paints, varnishes, and coatings.

N butanol helps to dissolve pigments, resins, and other additives, ensuring that the paint can be applied smoothly and evenly.
N butanol also contributes to the drying and curing process in certain types of coatings.
In the printing industry, N butanol is utilized in the production of inks, including flexographic and gravure printing inks, due to its excellent solvency properties.

N butanol aids in achieving the desired viscosity and flow characteristics.
N butanol is used as a solvent in the textile industry for dyeing and printing fabrics.
N butanol helps dissolve dyes and provides even color distribution.

N butanol is utilized in the rubber industry as a processing aid and solvent for rubber compounds.
N butanol is sometimes used as a component in wood coatings and finishes, providing protection and a smooth finish to wood products.
In addition to inks, N butanol can be found in fountain solutions and press wash solutions in the printing industry to help maintain the quality of printing presses.

While N butanol itself is not commonly used as a fuel, it is a precursor in the production of biofuels, such as butanol-based biofuels, which have been explored as potential alternatives to traditional fossil fuels.
N butanol is used as a cleaning agent in the electronics industry to remove contaminants from electronic components and printed circuit boards.
In recent years, there has been an increasing interest in water-based coatings and paints due to environmental considerations.

N butanol is sometimes used in water-based formulations as a coalescing agent to improve film formation and performance.
In scientific laboratories, N butanol can be used as a reagent or solvent in various chemical and biochemical experiments.
N butanol is used in the extraction and processing of oil and natural gas, particularly in the removal of impurities and as a solvent for certain chemical reactions.

N butanol has been used as a component in firefighting foams due to its ability to create stable foam and suppress flammable liquid fires.
Some automotive care products, such as windshield washer fluids, may contain N butanol as a component to help dissolve dirt and improve cleaning efficiency.
In the past, N butanol was used in the formulation of photographic chemicals, particularly in the development process, although its use in this application has decreased with the transition to digital photography.

N butanol can be used in agriculture as an adjuvant in pesticide formulations to improve the effectiveness and adhesion of pesticides to plant surfaces.
N butanol is a common ingredient in the manufacturing of adhesives and sealants, where it helps maintain the desired consistency and provides good adhesion properties.
N butanol is used as a reaction medium in various chemical processes, such as esterification reactions to produce esters used in perfumes and flavorings.

N butanol is used as a solvent in the extraction of natural fragrances and flavors, and it may also be found in the final formulations of perfumes, colognes, and food flavorings.
N butanol serves as a solvent in the production of pharmaceuticals and can be used in the synthesis of various active pharmaceutical ingredients (APIs).
In addition to being an octane booster in gasoline, N butanol can also be used as a component in the formulation of automotive fluids, such as brake fluids and hydraulic fluids.

N butanol can be employed as a plasticizer in the manufacture of plastics and rubber products, helping to improve their flexibility and durability.
As part of efforts to develop sustainable and bio-based fuels, N butanol has been investigated as a potential biofuel candidate.
N butanol can be produced through microbial fermentation processes using biomass feedstocks.

N butanol may be used in the production of food packaging materials, such as coatings on paper or films, to improve barrier properties and performance.
In laboratories, N butanol can be used as a solvent for various analytical techniques, including chromatography and spectrophotometry.
N butanol is used in the extraction of essential oils from plant materials and herbs for use in aromatherapy and natural products.

N butanol can be found in some cosmetics and personal care products, including nail polish and hair sprays.
In some industrial applications, N butanol may be used as a preservative to extend the shelf life of certain products.

Safety Profile:
A poison by intravenous route.
N butanol a flammable fight fire, use foam, CO2, dry chemical.
Contact, ingestion, subcutaneous, and intraperitoneal routes.

Human systemic Reported in EPA TSCA Inventory.
N butanol a skin and eye irritant.
When heated to decomposition it emits acrid and irritating fumes.

N butanol effects by inhalation: conjunctiva irritation, unspecified respiratory system effects, and nasal effects.
Incompatible with oxidzing materials.

Health And Fire Hazard:
Most vapors are heavier than air.
They will spread along ground and collect in low or confined areas (sewers, basements, tanks).
Chronic exposureof humans to high concentrations may causephotophobia, blurred vision, and lacrimation.

A concentration of 8000 ppm was maternallytoxic to rats, causing reduced weightgain and feed intake.
Vapor explosion hazard indoors, outdoors or in sewers.
Runoff to sewer may create fire or explosion hazard.

N butanol will be easily ignited by heat, sparks or flames.
Vapors may form explosive mixtures with air.
Vapors may travel to source of ignition and flash back.

The toxicity of N butanol is lower than thatof its carbon analog.
Target organs are theskin, eyes, and respiratory system.
Inhalationcauses irritation of the eyes, nose, and throat.

N butanol was found to cause severe injury to rabbits’eyes and to penetrate the cornea uponinstillation into the eyes.
Teratogenicity wasobserved at this concentration with a slightincrease in skeletal malformations.
In a single acute oral dose, the LD50 value(rats) is 790 mg/kg; in a dermal dose theLD50 value (rabbits) is 4200 mg/kg.

N butanol is oxidized in vivo enzymaticallyas well as nonenzymatically and iseliminated rapidly from the body in the urineand in expired air.
N butanol inhibits the metabolismof ethanol caused by the enzyme alcoholdehydrogenase.
Based on the available data, the useof N butanol as an ingredient is consideredsafe under the present practices andconcentrations in cosmetic nail products(Cosmetic, Toiletry and Fragrance Association1987a).

Synonyms:
N butanol
butanol
Butan-1-ol
N butanol
Butyl alcohol
71-36-3
n-butyl alcohol
1-hydroxybutane
Propylcarbinol
Butyl hydroxide
Methylolpropane
Propylmethanol
Hemostyp
Butyric alcohol
1-Butyl alcohol
n-Butan-1-ol
Butanolo
Propyl carbinol
Alcool butylique
Butylowy alkohol
BuOH
Butanolen
Normal primary butyl alcohol
Butanols
RCRA waste number U031
CCS 203
n-Butylalkohol
Alcohol, Butyl
Butyl alcohol (natural)
FEMA No. 2178
FEMA Number 2178
n-Propyl carbinol
1 Butanol
Butanol [French]
Butanolen [Dutch]
Butyric or normal primary butyl alcohol
Butanolo [Italian]
n-BuOH
35296-72-1
HSDB 48
NSC 62782
CCRIS 4321
Alcool butylique [French]
Butylowy alkohol [Polish]
butanol-1
EINECS 200-751-6
UNII-8PJ61P6TS3
Butanol, 1-
8PJ61P6TS3
Butyl alcohol (NF)
Butyl alcohol [NF]
ALCOHOL,BUTYL
DTXSID1021740
CHEBI:28885
AI3-00405
n-Butyl--d6 Alcohol
MFCD00002964
NSC-62782
RCRA waste no. U031
UNII-WB09NY83YA
n-Butyl-1,1-d2 Alcohol
N butanol-4,4,4-d3
CHEMBL14245
DTXCID701740
EC 200-751-6
NCGC00090961-02
Tilcom TNBT
Tyzor BP
Butyl orthotitanate
Tyzor BTM
Tyzor TBT
N butanol-3,3,4,4,4-D5
Orgatix T 25
Orgatix TA 25
Titanium tetrabutoxy-
BUTYL ALCOHOL (II)
BUTYL ALCOHOL [II]
Titanium tetrabutoxide
Titanium tetrabutylate
Tetra-n-butoxytitanium
Tetra-n-butil titanato
Tetra-n-butyl titanate
Titanium, tetrabutoxy-
32586-14-4
64118-16-7
Tetrabutoxytitanium(IV)
Tetrabutyl orthotitanate
N butanol, analytical standard
BUTYL ALCOHOL (MART.)
BUTYL ALCOHOL [MART.]
titanium tetra-n-butoxide
N butanol-2,2,3,3,4,4,4-D7
Titanium(IV) n-Butoxide
TETRABUTYL TITANATE
titanato de butilo (IV)
1219794-84-9
C(CC)CO
Tetrakis(butanolato)titanium
VANADIUM TETRABUTOXIDE
N butanol, Butan-1-ol, N butanol
TBT-B 1
Tetraortotitanato de n-butilo
n Butanol
Titanium tetrakis(1-butoxide)
n Butyl Alcohol
Titanic acid, tetrabutyl ester
N butanol, titanium(4) salt
C4H10O.1/4Ti
Titanium butoxide (Ti(OBu)4)
N butanol, ACS reagent, >=99.4%
N butanol, titanium(4+) salt
CAS-71-36-3
Alcohol, n-Butyl
Butyl titanate(IV) (6CI7CI)
AKT 850
Butyl alcohol, titanium(4) salt
TBT 100
N butanol titanium salt (4:1)
N butanol, titanium(4++) salt
1BO
Butyl alcohol, titanium(4+) salt
Butyl titanate(IV) ((BuO)4Ti)
C4-H10-O.1/4Ti
N butanol, sal de titanio (4 +)
N butanol titanium(4+) salt (9CI)
Tetrabutyl titanate; (Butyl titanate)
Butyl alcohol titanium(4+) salt (8CI)
TRIBUTYL ACETYLCITRATE IMPURITY D (EP IMPURITY)
TRIBUTYL ACETYLCITRATE IMPURITY D [EP IMPURITY]
N butanol, sal de titanio (4 +) (4:1)
butaneol
butylalcohol
propilcarbinol
butyl-alcohol
n-butylalcohol
normal butanol
1-butylalcohol
n-Propylcarbinol
alcohol n-butilo
N butanolbutanolen
nBuOH
1 -butanol
1- butanol
1-N butanol
Butyl alcohol, n-
N butanol, anhydrous
Butan- 1- ol
Butyl alcohol (8CI)
butan - 1 - ol
N-Butyl Alcohol,(S)
BAN (CHRIS Code)
N butanol, for HPLC
N butanol, HPLC grade
N butanol, 99%
6167-45-9
B 1
N butanol, HPLC Grade
n-C4H9OH
bmse000447
N butanol (butyl alcohol)
N butanol, 99.9%
BUTYL ALCOHOL [FCC]
WB09NY83YA
BUTYL ALCOHOL [FHFI]
BUTYL ALCOHOL [HSDB]
WLN: Q4
butan-1-olate,vanadium(4+)
N butanol [USP-RS]
ALCOHOL,BUTYL [VANDF]
BIDD:ER0611
N-BUTYL ALCOHOL [MI]
N-BUTYL ALCOHOL [INCI]
N butanol, LR, >=99%
BDBM36173
N butanol, anhydrous, 99.8%
N butanol, ACS, 99.4+%
N-BUTYL ALCOHOL [WHO-DD]
N butanol, AR, >=99.5%
N butanol, for HPLC, 99.8%
Butyl alcohol, >=99.9%, FCC
NSC62782
Tox21_111046
Tox21_200741
LMFA05000109
STL264186
AKOS000249218
N butanol 500 microg/mL in Methanol
N butanol, for HPLC, >=99.7%
DB02145
LS-1603
Butyl alcohol, >=99.9%, FCC, FG
NCGC00090961-01
NCGC00090961-03
NCGC00258295-01
BP-30034
N butanol, SAJ first grade, >=99.0%
N butanol, for molecular biology, >=99%
N butanol, JIS special grade, >=99.0%
N butanol, p.a., ACS reagent, 99.4%
N butanol, for HPLC, >=99.8% (GC)
N butanol, spectrophotometric grade, 99.5%
N butanol, UV HPLC spectroscopic, 99.5%
B0228
B0704
B0944
FT-0607555
FT-0623296
FT-0774976
N butanol, anhydrous, ZerO2(TM), 99.8%
EN300-19305
N butanol, Ultrapure, Spectrophotometric Grade
Butyl alcohol, natural, >=99.5%, FCC, FG
C06142
D03200
Q16391
VOC Mixture 582 2000 microg/mL in Methanol
F0001-1830
InChI=1/C4H10O/c1-2-3-4-5/h5H,2-4H2,1H
N butanol, puriss. p.a., ACS reagent, >=99.5% (GC)
BDBC6468-886D-4F6C-8746-734F2B63E6CE
N butanol, ACS reagent, reag. ISO, reag. Ph. Eur., 99.5%
N butanol, United States Pharmacopeia (USP) Reference Standard
N butanol, Pharmaceutical Secondary Standard; Certified Reference Material
N butanol, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., >=99.5% (GC)

N HANCE C261
N Hance C261 is an organic compound that is a water-soluble quaternary ammonium derivative of guar gum.
N Hance C261 gives conditioning properties to shampoos and after-shampoo hair care products.


CAS Number: 65497-29-2
EC Number: 613-809-4
Classification: Quaternary ammonium cation, Propoxylated compound, Bio-compatible
Origin(s): Vegetal, Synthetic
INCI name: GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE
Chem/IUPAC Name: Guar gum, 2-hydroxy-3-(trimethylammonio)propyl ether, chloride
Molecular Formula: C6H16NO2



SYNONYMS:
Keratrix, Aquacat CG518, Aquacat IC, Aquacat PF618, N-Hance 3000 Cationic Guar, N-Hance 3196 Cationic Guar, COSMEDIA Guar C 261, COSMEDIA Guar C 261 N, DEHYQUART Guar HP, DEHYQUART Guar N, DEHYQUART Guar TC, Dermatein Power Powder IV - Lustre, COSMOROL GQ6, Fibroforce, GoBlond, Seridefrizz Intense Salon, Seriseal, Seriseal DS, DOWSIL CE 2060 Emulsion, ECOPOL -13, ECOPOL -13S, ECOPOL -14, ECOPOL -14S, ECOPOL -17, ACEROMINE, ROSAMINE, Hony 103, GUAR 13S, GUAR 14S, Guangzhou Tinci Materials Technology (Tinci), GUAR 15S, Activsoft C-14, Activsoft C-17, Finsoft C-13, Finsoft C-14, Finsoft C-17, Guarsafe® JK-110, Guarsafe® JK-110H, Guarsafe® JK-130, Guarsafe® JK-140, Guarsafe® JK-141, SI6037Z (D), SI6400Z (D), SeraShine® EM 503, SeraShine® EM 504, Vida-Care GHTC 03, KY-286, KY-286-N, KY-286-S, Kiyu New Material, KY-386, KY-386-N, Cesmetic DP 101, Cesmetic DP 105, Cesmetic DP 109, Esaflor BF 2, Esaflor BF 7, Esaflor EC 3, Esaflor EC 4, Catcol® Guar Hydroxypropyltrimonium chloride hydroxypropyl, Catcol® Guar hydroxypropyltrimonium chloride, MICONIUM CG-L200, MICONIUM CG-L45, MICONIUM CG-M35N, Armocare® G113, Armocare® G114, POLYCOS CA-3000, POLYCOS CA-3001, POLYCOS CA-3002, POLYCOS CA-3003, POLYCOS CA-3004, Resoft 14S, SMAGUAR CAT-110, SMAGUAR CAT-130, SMAGUAR CAT-140, SMAGUAR CAT-170, SMAGUAR SUPREME, Hi-Care® 1000, Jaguar® C-1000, Jaguar® C-13-S, Jaguar® C-14-S, Jaguar® C-17, SC-14-S Cationic Guar Gum, SUNCOS-CG 2018D, SUNCOS-CG 3015D, SUNCOS-CG 3515, SUNCOS-CG 3515D, SUNCOS-CG 520D, GuarSilk™, Thorcoquat 12S, Thorcoquat 13S, Thorcoquat 14S, Thorcoquat 15S, Cationic Guar, Guar hydroxypropyl trimethyl ammonium chloride, Cationic Guar Gum, Guar Hydroxypropyltrimnonium Chlide, gumguar2-hydroxy-3-(trimethylammonio)-propylet, jaguarc13s, GUM GUAR 2-HYDROXY-3-(TRIMETHYLAMMONIO)&, cosmediaguarc261, Guar,2-hydroxy-3-trimethylammoniopropylether,chloride Cationic Guar Gum, jaguarc15, jaguarc17, jaguarc14s, jaguarc13s, cosmediaguarc261, Guar Hydroxypropyltrimnonium Chlide, Guar hydroxypropyltrimonium chloride, Guar Hydroxypropyltiamonium Chloride, Guar Hydroxypropyl Trimoniun Chloride, GUM GUAR 2-HYDROXY-3-(TRIMETHYLAMMONIO)&, cosmediaguarc261, Guar,2-hydroxy-3-trimethylammoniopropylether,chloride, Guargum,etherwith3-chloro-2-hydroxypropyltrimethylammoniumchloride, Guar-hydroxypropyltrimethylammoniumchlorid (mittlere Molmasse ca. 220 000 g/mol), Guar hydroxypropyl trimethyl ammonium chloride, Cationic Guar Gum, Guar Hydroxypropyltrimnonium Chlide, C-130, C-140(LPH), SYNERGUAR SN-1410, GUM GUAR 2-HYDROXY-3-(TRIMETHYLAMMONIO), cosmediaguarc261, Guar,2-hydroxy-3-trimethylammoniopropylether,chloride, Guargum,etherwith3-chloro-2-hydroxypropyltrimethylammoniumchloride, gumguar2-hydroxy-3-(trimethylammonio)-propylet, jaguarc13s, jaguarc14s, jaguar, Guar gum, 2-hydroxy-3-(trimethylammonio)propyl ether, chloride, Guar Gum, 2-Hydroxypropyl 2-Hydroxy-3-(Trimethylammonio)Propyl Ether Chloride, Guar, 2-hydroxy-3-trimethylammoniopropyl ether, chloride, Guar gum, 2-hydroxy-3-(trimethylammonio)propyl ether, chloride, Cationic Guar Gum, Guar Hydroxypropyltrimonium Chloride, Guar gum, 2-Hydroxy-3-(trimethylammonio)propyl Ether, Chloride, Guar Hyd Prop Trimonium Chlor, Guar Hydroxy Propyl Trimonium Chloride, T/N: Esaflor EC4, Trimethylammoniopropyl Guar Chloride 100%, Unguar C461



N Hance C261 is an organic compound that is a water-soluble quaternary ammonium derivative of guar gum.
N Hance C261 gives conditioning properties to shampoos and after-shampoo hair care products.
The effects of the cationic charge density, guar concentration in aqueous solution, and treatment time on bleached European hair have been studied.


A mechanical testing method has been successfully applied to determine the efficacy of cationic guars to improve the ease of combing.
The results were confirmed in a shampoo formulation on both virgin and bleached hair.
N Hance C261 is catioinic modified polysaccharide derived from natural guar.


N Hance C261 can be used in paper making as binder to maximize the retention of the filler and cellulosic fines in the sheet so that the pollution problems and the amount of valuable substances in the white water are reduced.
N Hance C261 also improve paper strength and evenness.


Among these guar ingredients, N Hance C261 is most frequently used in cosmetic products.
N Hance C261 is a water-soluble, organic compound that is a quaternary ammonium derivative of guar (aka cluster beans).
This means N Hance C261 is a substance whose chemical structure has four carbon groups attached to a positively charged nitrogen atom.


While plant derived, there is a synthetic portion to N Hance C261.
N Hance C261 is a quaternary ammonium derivative of guar gum.
N Hance C261 is an antistatic, film forming, skin conditioning, viscosity controlling ingredient.


N Hance C261 is a cationic surfactant that has been shown to be effective in the treatment of vaginal atrophy.
N Hance C261 has been shown to be an excellent antimicrobial agent for the prevention and treatment of microbial infection.
N Hance C261 is an organic compound that is a water-soluble quaternary ammonium derivative of guar gum.


N Hance C261 has also been used as a detergent additive.
The hydroxyl group on N Hance C261 interacts with fatty acids, causing it to form a complex with citric acid, which increases its effectiveness in reducing bacterial populations.


The citric acid-N Hance C261 complex also inhibits the growth of gram-positive bacteria such as Staphylococcus and Streptococcus species.
N Hance C261 is a guar gum derivative modified from natural guar beans and is known under the INCI name Guar Hydroxypropyltrimonium Chloride.
N Hance C261 is a cationic surfactant that has been shown to be effective in the treatment of vaginal atrophy.


N Hance C261 has been shown to be an excellent antimicrobial agent for the prevention and treatment of microbial infection.
N Hance C261 has also been used as a detergent additive.
The hydroxyl group on N Hance C261 interacts with fatty acids, causing it to form a complex with citric acid, which increases its effectiveness in reducing bacterial populations.


N Hance C261 is identified as a white or yellow like powder.
With N Hance C261 you can get non-static silky hair.
N Hance C261 also helps it retain volume and makes it easier to manage.


So basically N Hance C261 is amazing for your hair.
N Hance C261, GHPT for short, is a water-soluble quaternary ammonium modifier of guar gum.
N Hance C261 is a compound that is water soluble.


N Hance C261 is a water-soluble, organic compound that is a quaternary ammonium derivative of guar (aka cluster beans).
This means N Hance C261 is a substance whose chemical structure has four carbon groups attached to a positively charged nitrogen atom.
While plant derived, there is a synthetic portion to N Hance C261.


Although a great conditioning agent for both hair and scalp, N Hance C261 most definitely gives the biggest benefits to your strands of hair.
N Hance C261 is a cationic surfactant that has been shown to be effective in the treatment of vaginal atrophy.
The citric acid-N Hance C261 complex also inhibits the growth of gram-positive bacteria such as Staphylococcus and Streptococcus species.


N Hance C261 is an organic compound that is a water-soluble quaternary ammonium derivative of guar gum.
N Hance C261 gives conditioning properties to shampoos and after-shampoo hair care products.
N Hance C261, with the CAS registry number 65497-29-2, is also known as Guar, 2-hydroxy-3-trimethylammoniopropyl ether, chloride.


What's more, its systematic name is N Hance C261, 2-hydroxy-3-(trimethylammonio)propyl ether, chloride.
N Hance C261 is an organic compound that is a water-soluble quaternary ammonium derivative of guar gum.
N Hance C261 should be sealed and stored in a cool and dry place.


N-hance cationic guars are cationic polymers that provide the dual benefits of conditioning and thickening.
The cationic charge makes the product substantive to anionic surfaces such as skin and hair.
Many of the products in the n-hance cationic guar product line have a high molecular weight, water-soluble backbone and are effective viscosifiers in aqueous solutions and surfactant-based systems.


N Hance C261 is a yellow free-flowing powder
N Hance C261 is an organic compound that is a water-soluble quaternary ammonium derivative of guar gum.
N Hance C261 gives conditioning properties to shampoos and after-shampoo hair care products.


N Hance C261 is a hydroxypropylated cationic guar derivative that provides conditioning benefits.
The cationic charge of N Hance C261 interacts with keratin providing a conditioning effect on hair and skin and reducing the negative effects of soaps and surfactants.


Though cationic, N Hance C261 is compatible with most anionic and amphoteric surfactants.
N Hance C261 is not sensitive to electrolytes and due to the hydropropylation shows higher hydrophilic characteristics when compared to other cationic guars.


N Hance C261 is soluble in water at room temperature (pH adjusted to 5.5-6.0), partially soluble in aqueous methanol or ethanol solutions and insoluble in paraffin oil, petroleum ether, chloroform and ethyl ether.
Cyamopsis Tetragonoloba (Guar) Gumb (also called Guar Gum) is a resinous material made from the guar bean.


N Hance C261 has been shown to be an excellent antimicrobial agent for the prevention and treatment of microbial infection.
N Hance C261 is a quaternary ammonium derivative of guar gum; used in hair conditioning products.
N Hance C261 is used conditioning chemical added to hair products for easy detangling


N Hance C261 (GHPC) is a cationic surfactant that has been shown to be effective in the treatment of vaginal atrophy.
N Hance C261 has been shown to be an excellent antimicrobial agent for the prevention and treatment of microbial infection.
N Hance C261 is made of natural guar gum modified.


N Hance C261 is an organic compound with charged properties, derived from guar gum.
N Hance C261 acts as a conditioning agent for skin and hair, it also has antistatic properties.
N Hance C261 is part of synthetic molecules, an exception in the COSMOS specifications: it is therefore authorized in organic.


Note that N Hance C261 is obtained from the seed of a legume (Cyamopsis tetragonoloba).
Read "N Hance C261" on the ingredient list of your shampoo and you might get concerned, but actually, this ingredient with the scary name is actually very safe.


N Hance C261 is a water-soluble, organic compound.
N Hance C261 is plant derived from the guar (cluster bean) plant.
Although it is plant based, there is a synthetic portion to it.


N Hance C261 is grown in India and Pakistan.
N Hance C261 acts as a thickener and conditioning agent.
N Hance C261 is a cationic polymer substantive to anionic surfaces such as hair and skin.


N Hance C261 is cold processabl & offers a smooth, soft and silky feel to the hair.
N Hance C261 provides tangle-free wet and dry comb.
N Hance C261 helps maintain moisture on the skin after rinsing.


N Hance C261 is a yellow or white powdered ingredient that is obtained from guar beans.
N Hance C261 is generally used in shampoos and other hair products where it acts as a conditioner and an anti-static agent.
The chemical formula of N Hance C261 is C6H16NO2.


Further, N Hance C261 is used as a substitute for harsh silicones.
N Hance C261 is a kind of cationic polymer, that provides excellent thickening and conditioning properties for hair and skin care products.
N Hance C261 is derived from the seeds of guar plant scientifically known as chamois tetragonolobus, and it contains a high molecular weight sugar/ polysaccharide called as galactomannan.


N Hance C261 comes as a yellowish powder, with characteristic but faint odor.
N Hance C261 is a white or yellow fine powder derived from guar beans.
N Hance C261 is a kind of galactomannan, which is a polysaccharide.


N Hance C261 is a naturally derived cationic polymer that is commonly used as a conditioning agent in shampoos, cream rinse conditioners, shower gels, body washes, and skin cleanser formulas.
N Hance C261 is derived from the guar bean, the polymer's backbone is a Mannose-Galactose Polysaccharide that has been cauterized to enhance substantivity to hair and skin.


N Hance C261 is a yellow, free-flowing powder with a slight amine odor.
N Hance C261 is a yellow or white powdered ingredient that is obtained from guar beans.
N Hance C261 is generally used in shampoos and other hair products where it acts as a conditioner and an anti-static agent.


N Hance C261 is a plant-based ingredient that is extracted from guar beans.
Even though it is sourced from natural means, N Hance C261 is still synthetic because of the way it is made.
After the extraction process is complete and a natural gum has been obtained from the guar beans, N Hance C261 is then purified and filtered.


After this, the natural gum is reacted with epoxides to make N Hance C261.
N Hance C261 is an organic compound that is a water-soluble quaternary ammonium derivative of guar gum.
N Hance C261 gives conditioning properties to shampoos and after-shampoo hair care products.


The effects of the cationic charge density, N Hance C261 concentration in aqueous solution, and treatment time on bleached European hair have been studied.
A mechanical testing method has been successfully applied to determine the efficacy of cationic guars to improve the ease of combing.
The results were confirmed in a shampoo formulation on both virgin and bleached hair N Hance C261 is modified from Guar gum.


Add N Hance C261 into cold water, stir until dispersed, add citric acid until pH<7, stir until thickened.
N Hance C261 is generally considered safe.
N Hance C261 can cause a mild allergic reaction in the form of irritated skin for some with sensitive skin.


This mostly depends on the amount used in the formula...N Hance C261 should not exceed 1.0%.
Remember, the farther down the list of ingredients, the smaller the amount.
N Hance C261 is a great conditioning agent for both skin and hair.


N Hance C261 has charged properties that make it especially useful in hair care formulations.
N Hance C261 is cationic (positively charged) and works by neutralizing the negative charges on hair strands that cause static and tangling.
N Hance C261 is a quat (quaternary ammonium) synthetic derived from Guar gum.



USES and APPLICATIONS of N HANCE C261:
N Hance C261 is an anti-irritant and anti-inflammatory that is also used as a thickening, conditioning, and anti-static agent.
Better yet, N Hance C261 does this without weighing hair down.
With N Hance C261, you can have silky, non-static hair that retains its volume and provides a smoother brushing experience.


Also, N Hance C261 enhances wet comb and dry comb properties in shampoos and hair conditioning systems.
Unlike similar ingredients, N Hance C261 is self-hydrating in water and does not require acidification during use.
N Hance C261 forms a coacervate with anionic surfactants from the shampoo formulation upon dilution and deposits on the surface of hair providing conditioning in the form of reduced wet combing forces.


The dilution and deposition phenomenon occurs when the system is diluted below the critical micelle concentration of the shampoo surfactants, resulting in the formation of the insoluble coacervate.
The properties of the formed coacervate depend on a variety of characteristics of N Hance C261, including molecular weight and charge density, as well as the composition of surfactants and presence of electrolytes.


In addition, N Hance C261 has reported uses in liquid soap and body wash formulations, hair conditioners, hair styling products, and skin care preparations.
N Hance C261 helps maintain a product’s smoothing action.
Some manufacturers cite N Hance C261 as also having skin-softening capabilities.


N Hance C261 has also been used as a detergent additive.
The hydroxyl group on N Hance C261 interacts with fatty acids, causing it to form a complex with citric acid, which increases its effectiveness in reducing bacterial populations.


The citric acid-N Hance C261 complex also inhibits the growth of gram-positive bacteria such as Staphylococcus and Streptococcus species.
N Hance C261 may be used in bath products, hair conditioners, hair dyes, other hair care products and skin care products.
N Hance C261 is a water-soluble derivative of natural guar gum and delivers conditioning properties to shampoos and after-shampoo hair care products.


N Hance C261 is mainly used to give conditioning benefits to surfactant based formulations such as shampoos, body washes and shaving preparations.
N Hance C261 is substantive to the hair where it has been proven to reduce tangling, improve hair feel, styling ability and gloss.
As this turns solutions cloudy N Hance C261 is best suited for pearlescent or coloured formulations or emulsions.


A conditioning chemical added to hair products for easy detangling
N Hance C261 is a water-soluble derivative of natural guar gum, and delivers conditioning properties to shampoos and after-shampoo hair care products.
N Hance C261 imparts excellent skin conditioning in creams or lotions that otherwise may not be used on the face.


Key applications of N Hance C261: Hair care, Shampoo, Personal care, Cosmetic products, Soaps and detergents, Beauty products, Industries, and Cosmetics
N Hance C261 has also been used as a detergent additive.
The hydroxyl group on N Hance C261 interacts with fatty acids, causing it to form a complex with citric acid, which increases its effectiveness in reducing bacterial populations.


The citric acid-N Hance C261 complex also inhibits the growth of gram-positive bacteria such as Staphylococcus and Streptococcus species.
In personal care industry N Hance C261's usually used as conditioner, thickeners and stabilizers, also it's widely used in shampoo, shower gel, liquid soap, cream and other products since it has good compatibility in the formula.


N Hance C261 is often used as an anti-static agent and skin or hair conditioner; it also increases viscosity.
N Hance C261 is also found in hundreds of personal care products, such as shampoo, conditioner, dandruff treatments, styling products, soap, hairspray, and other products.


N Hance C261 is used as a hair detangler.
N Hance C261 adds lubricity to a product when in contact with the skin.
There is some evidence that N Hance C261 can enhance a formulation’s viscosity and stability.


N Hance C261 is a derivative of guar gum.
N Hance C261 is widely used as a conditioning agent in personal care products, it is a cationic polymer that provides substantivity and compatibility with anionic surfactants.


N Hance C261 is commonly used as a conditioning agent in shampoo formulations with prominent anti-irritant, anti-inflammatory, and anti-static properties.
Additionally, N Hance C261 also functions as a thickening agent in hair care formulations.
N Hance C261 can observably enhance a formulation’s viscosity and stability.


N Hance C261 is a cationic derivative of guar gum with excellent compatibility with anionic surfactant systems, which makes it a perfect choice for making 2-in-1 conditioning shampoos.
N Hance C261's positive-charged head bonds with the negative-charged hair keratin after being washed by anionic surfactants and form a 'free-breathing' thin film on hair and skin.


Such a film then provides protection and conditioning to our hair and skin.
The reason being is that it’s positively charged, also known as cationic.
This means that N Hance C261 neutralises the negative charges on hair strands that cause hair to become static or tangled.


The result, easier combing, reduced frizz and minimised flyaways.
N Hance C261 is also a lightweight ingredient as its often used in place of other anti-static ingredients that are heavier which weigh the hair down, which is especially an issue on finer hair.


N Hance C261 is used in shampoos and hair conditioners and can be used in both leave in and rinse out products.
N Hance C261 helps maintain moisture on the skin after rinsing and is often used in body washes, shower gels and liquid soaps.
For hair products, N Hance C261 can be used for many different hair types - from normal to oily to ethnic and can provide anti-dandruff, repair, volumizing and detangling benefits.


N Hance C261 is a conditioning agent for all kind of hair care preparations.
N Hance C261 can also be used in personal care products to thicken formulations and provide skin-conditioning benefits.
N Hance C261 is a quaternary ammonium derivative of guar gum; used in hair conditioning products.


Typically used in formulations at 0.10% to 0.50% concentration levels, N Hance C261 is entirely compatible with most common anionic, cationic, and amphoteric surfactants and is ideally suited for use in two-in-one conditioning shampoos and moisturizing skin cleansing products.
When used in personal cleansing formulations, N Hance C261 imparts a soft, elegant after-feel to the skin.


Cosmetic Uses: N Hance C261 is used antistatic agents, film formers, skin conditioning, and viscosity controlling agents.
Key applications of N Hance C261: N Hance C261 is used Hair care, Shampoo, Personal care, Cosmetic products, Soaps and detergents, and Beauty products.
Applications of N Hance C261: Two-in-one shampoos, Cream rinse conditioners, Styling gels and mousses Facial cleansers, Shower gels and body washes, Liquid hand soaps, and Bar soaps.


N Hance C261 is commonly used as a conditioning agent in shampoo formulations.
N Hance C261 is also used in skin care products where it deeply conditions the skin.
N Hance C261 is used in normal, anti-dandruff, color/treated and ethnic hair shampoos.


N Hance C261 is used to impart creaminess.
N Hance C261 is thus added to dairy products.
N Hance C261 also is used in place of ingredients that contain gluten.


The best known food in which this has occurred is certain breads.
N Hance C261 is especially beneficial as a hair care product.
Because N Hance C261 is positively charged, or cationic, it neutralizes the negative charges on hair strands that cause hair to become static or tangled.


N Hance C261 is also used for conditioners & volumizers, body washes, shower gels and liquid soaps.
N Hance C261 has been widely used in Cosmetics & Toiletries industry with applications (such as being conditioner, viscosifier and flotation stabilizer, etc.) in translucent shampoo, body wash, facial cleanser, shaving gel.


N Hance C261 is also used in skin care products where it deeply conditions the skin.
The chemical formula of N Hance C261 is C6H16NO2.
Further, N Hance C261 is used as a substitute for harsh silicones.


Applications include Hair care, Shampoo, Shower gel.
N Hance C261 is used light conditioning, shampoos, and volumizing shampoos.



USE AND BENEFITS of N HANCE C261:
N Hance C261 is a large molecule, so it is used to provide a thickening effect in the formulation.
However,N Hance C261 does not form a gel only to increase viscosity, which can be considered a special feature of it.

Another problem sometimes with thickeners is, they impair the foaming effect of surfactant, but in case of the guar gum, Guar Hydroxypropyltrimonium
Chloride enhances the foaming effect, that makes it an ideal choice for shampoos, handwashes, and body washes.

Also being a sugar molecule, N Hance C261 can attract and hold water molecules, even when applied on skin or hair, which results in conditioning effect on dry hair and skin.
The guar gum is mostly available as quaternary ammonium salt- N Hance C261, which is a quite stable form of guar gum.

N Hance C261 provides more conditioning effect that normal form of guar gum.
N Hance C261 is used in lotions, creams, body washes, shampoos, conditioners, shower gels, etc.



APPLICATION AND CHARACTERISTICS of N HANCE C261:
N Hance C261 is a natural guar gum’s cationic replacement.
N Hance C261 contributes excellent thickness and conditioning effect to hair care products and skin care products.

N Hance C261 improves wet and dry combability and keep hair lubricity, soft, sparingly.
N Hance C261 reduces stimulate of washings to skin and imparts slip and comfortable feeling.

N Hance C261 is used with polyquaternium-7, polyquaternium-49(M-550,M-2001), its’ conditioning will be more excellent.
N Hance C261 is mainly used in pearl shampoo, washing liquid, cream, liquid soap and care products.
When compound the solvent, disperse N Hance C261 in the water on mix.

After N Hance C261 dissolve in water the viscosity will be increasing slowly.
If use citric acid to revise pH to 6, N Hance C261’s viscosity will be increasing immediately.
The supposed concentration of N Hance C261 is 0.2 – 0.5%.



WHAT IS N HANCE C261 USED FOR?
The main function of N Hance C261 is to extend conditioning properties to hair care products.
N Hance C261 is also sometimes used in skin care products to achieve the same results.

*Hair care:
N Hance C261 is a positively charged ingredient, that cancels the negative charge on hair causing it to have a static or become tangled.
N Hance C261 makes the hair silky smooth without weighing them down

*Skin care:
N Hance C261 nourishes the skin and also increases the viscosity of the formulations



WHAT IS N HANCE C261 USED FOR?
The main function of N Hance C261 is to extend conditioning properties to hair care products.
N Hance C261 is also sometimes used in skin care products to achieve the same results.

*Hair care:
N Hance C261 is a positively charged ingredient, that cancels the negative charge on hair causing it to have a static or become tangled.
N Hance C261 makes the hair silky smooth without weighing them down

*Skin care:
N Hance C261 nourishes the skin and also increases the viscosity of the formulations



ORIGIN OF N HANCE C261:
N Hance C261 is a plant-based ingredient that is extracted from guar beans.
Even though N Hance C261 is sourced from natural means, it is still synthetic because of the way it is made.
After the extraction process is complete and a natural gum has been obtained from the guar beans, N Hance C261 is then purified and filtered.
After this, the natural gum is reacted with epoxides to make N Hance C261.



WHAT DOES N HANCE C261 DO IN A FORMULATION?
*Antistatic
*Hair conditioning
*Skin conditioning
*Viscosity controlling



SAFETY PROFILE OF N HANCE C261:
N Hance C261 is very safe and has almost no side effects.
N Hance C261 can cause minor irritation on highly sensitive skin.
Therefore, a patch test is recommended prior to use.
Other than this, there is no carcinogenicity or toxicity associated with N Hance C261.
Moreover, N Hance C261 is biodegradable.



ALTERNATIVES OF N HANCE C261:
*DIMETHICONE,
*FRUCTOSE,
*GLYCERIN,
*BEHENTRIMONIUM CHLORIDE



BENEFITS OF N HANCE C261:
*Great conditioning effects
*Soft and natural skin feeling
*Smoother brushing experience
*Lightweight ingredient prevents weighing hair down
*Natural guar gum origin



FEATURES AND BENEFITS OF N HANCE C261:
*Soluble in cold water
*Surface treated to delay hydration and allow good dispersion
*Natural origin and safe to use



CHARACTER OF N HANCE C261:
1.For hair care products: N Hance C261 is good foam stabilizing effect, anti-static effect .
N Hance C261 can associate the human hair keratin, improve the wet and dry combing performance and maintain hair's lustre, softness and elasticity for a long time.
For skin care products: N Hance C261 can reduce cleanser's irritation to skin and the lost of natural lipids of skin, protect keratin, make skin smooth and soft.



WHY IS N HANCE C261 USED?
Although a great conditioning agent for both skin and hair, N Hance C261 is especially beneficial as a hair care product.
Because it is positively charged, or cationic, N Hance C261 neutralizes the negative charges on hair strands that cause hair to become static or tangled.
Better yet, N Hance C261 does this without weighing hair down.
With N Hance C261, you can have silky, non-static hair that retains its volume.



IS N HANCE C261 A GOOD INGREDIENT FOR YOUR HAIR?
N Hance C261 is cationic, meaning positively charged.
This makes N Hance C261 an ideal ingredient to neutralize negative charges in your hair that leave it tangled or full of static.
N Hance C261 is also effective at reducing frizz and adding moisture.
*For the Environment:
N Hance C261 is biodegradable and has a very low tendency for bioaccumulation.



IS N HANCE C261 NATURAL OR SYNTHETIC?
N Hance C261 is sourced from the seeds of the guar plant, making it a natural ingredient and an organic compound.



FUNCTIONS of N HANCE C261 IN COSMETIC PRODUCTS:
ANTISTATIC:
N Hance C261 reduces electrostatic charges (eg of the hair)

FILM FORMING:
N Hance C261 produces a continuous film on skin, hair and / or nails

SKIN CONDITIONING:
N Hance C261 maintains the skin in good condition

VISCOSITY CONTROLLING:
N Hance C261 increases or decreases the viscosity of cosmetic products



WHAT DOES N HANCE C261 DO IN A FORMULATION?
*Antistatic
*Hair conditioning
*Skin conditioning
*Viscosity controlling



SAFETY PROFILE of N HANCE C261:
N Hance C261 is very safe and has almost no side effects.
N Hance C261 can cause minor irritation on highly sensitive skin.

Therefore, a patch test is recommended prior to use.
Other than this, there is no carcinogenicity or toxicity associated with N Hance C261.
Moreover, N Hance C261 is biodegradable.



FUNCTIONS of N HANCE C261:
• Antistatic
• Film forming
• Skin conditioning
• Viscosity controlling
• Conditioner
• Surfactant
• Emulsifier

N Hance C261 is a water-soluble derivative of natural.
Is an organic compound, N Hance C261, that is a water-soluble quaternary ammonium derivative of guar gum.
N Hance C261 gives conditioning properties to shampoos and after-shampoo hair care products.

*Antistatic :
N Hance C261 reduces static electricity by neutralizing electrical charge on a surface

*Film forming :
N Hance C261 produces a continuous film on skin, hair or nails

*Skin conditioning :
N Hance C261 maintains skin in good condition

*Viscosity controlling :
N Hance C261 increases or decreases the viscosity of cosmetics



FEATURES OF N HANCE C261:
*low viscosity
*low conditioning
*self hydrating



HOW N HANCE C261 IS MADE?
N Hance C261 production starts by milling guar beans to obtain the natural gum.
N Hance C261 is then purified, filtered, and reacted with epoxides.
One method involves converting guar with 3-chloro-2 hystroxyproply trimethyl ammonium chloride.



PROPERTIES of N HANCE C261:
N Hance C261 is a biopolymer.
Therefore, many of N Hance C261's properties will depend on its molecular weight and charge density, which is subject to the degree of cationic substition.

N Hance C261 is soluble in water.
N Hance C261 is insoluble in alcohol and oils.
The melting point of N Hance C261 is 170 ˚C.



BENEFITS of N HANCE C261:
*Yields nice viscous qualities
*Great conditioning agent
*Easier wet & dry combing
*Smoother brushing experience
*Natural guar gum origin
*Antistatic
*Detangles hair
*conditioning
*This cationic polymer, N Hance C261, is substantive to the hair where it improves wet and dry combability.
N Hance C261 is compatible with anionic, nonionic and cationic surfactants and is suitable for cold processing.



WHAT ARE THE BENEFITS of N HANCE C261 FOR THE SKIN OR HAIR?
*Enhanced ease of wet hair combing
*Enhanced comfort of dry hair combing
*Improved hair manageability
*Improved foam quality, stability, and texture
*Increased active delivery of silicone
*Impart soft, elegant after-feel to the skin from personal cleansing formulations



WHAT IS THE DIFFERENCE BETWEEN N HANCE C261 AND GUAR GUM?
When it comes to N Hance C261 vs guar gum, the former is a derived form of guar gum.
While also sourced from the guar plant, guar gum is a polysaccharide, while N Hance C261 is a chloride.



FEATURES AND BENEFITS of N HANCE C261:
*Low plant protein residues.
*Uniformity of substitution degree, low content of water insoluble matter.
*Low impurity content.
*Low residual etherifier content.
*High purity, good light transmittance, high tonality.



PHYSICAL and CHEMICAL PROPERTIES of N HANCE C261:
Melting Point: >300°C (lit.)
Solubility: Soluble in water
Viscosity: High
Molecular Formula: C6H16NO2.xCl.xUnspecified
Density: 1.3 g/mL at 25 °C (lit.)
Appearance: Yellow powder
Concentration: 0.2-1%
Important Criteria: Palm oil-free; Vegan; Animal non-testing; Non-GMO
Induction: Water phase

INCI: Hydroxypropyl Guar, Hydroxypropyltrimonium Chloride
Original Material: Guar gum
pH: 9-11
Scent: Characteristic
Appearance: Slight yellow powder
Odor: Minor characteristic odor
pH (1% aq): 8.0-11.0
Nitrogen Content (%): 1.3-1.7
Loss on Drying (%): ≤13
Ash (%): ≤3
Dispersion in Water: Good dispersibility in water
Melting point: >300 °C (lit.)

Density: 1.3 g/mL at 25 °C (lit.)
Odor: Odorless at 100.00%
EWG's Food Scores: 1
FDA UNII: B16G315W7A
EPA Substance Registry System: Guar gum, 2-hydroxy-3-(trimethylammonio)propyl ether, chloride (65497-29-2)
Appearance: Off-white to pale yellow powder
Moisture: 10% Max
Particle Size through US 100 mesh: Through US 200 mesh
Minimum Purity:
99.8% (4000~6000 mPa.s at 25 ℃, 1.0%, Brookfield, Spindle 3#, 12RPM)
95% (pH value: 6.0~ 10.0)



FIRST AID MEASURES of N HANCE C261:
-Description of first-aid measures:
*After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.



ACCIDENTAL RELEASE MEASURES of N HANCE C261:
-Environmental precautions:
No special precautionary measures necessary.
-Methods and materials for containment and cleaning up:
Observe possible material restrictions.
Take up with liquidabsorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of N HANCE C261:
-Extinguishing media:
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.



EXPOSURE CONTROLS/PERSONAL PROTECTION of N HANCE C261:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
not required
*Respiratory protection:
Not required.
-Control of environmental exposure:
No special precautionary measures necessary.



HANDLING and STORAGE of N HANCE C261:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.



STABILITY and REACTIVITY of N HANCE C261:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .


N HEPTANE
N HEPTANE = SEPTANE


CAS Number: 142-82-5
EC Number: 205-563-8
MDL Number: MFCD00009544
Chemical formula: C7H16 / CH3(CH2)5CH3


n heptane is a straight-chain alkane with seven carbon atoms.
n heptane has been found in Jeffrey pine (Pinus jeffreyi).
n heptane has a role as a non-polar solvent and a plant metabolite.
n heptane is a volatile organic compound and an alkane.


n heptane is a clear colorless liquids with a petroleum-like odor.
n heptane's flash point is 25 °F.
n heptane is less dense than water and insoluble in water.
n heptane's vapors heavier than air.


n heptane is a natural product found in Vitis rotundifolia, Patrinia villosa, and other organisms with data available.
Heptane or n-heptane is the straight-chain alkane with the chemical formula H3C(CH2)5CH3 or C7H16.
When used as a test fuel component in anti-knock test engines, a 100% heptane fuel is the zero point of the octane rating scale (the 100 point is 100% iso-octane).


Octane number equates to the anti-knock qualities of a comparison mixture of heptane and isooctane which is expressed as the percentage of isooctane in heptane and is listed on pumps for gasoline (petrol) dispensed globally.
Aqueous bromine may be distinguished from aqueous iodine by n heptane's appearance after extraction into it.
In water, both bromine and iodine appear brown.


However, iodine turns purple when dissolved in n heptane, whereas the bromine solution remains brown.
n heptane is found in cardamom.
n heptane is an alkane hydrocarbon with the chemical formula CH3(CH2)8CH3.
n heptane has 9 isomers, or 11 if enantiomers are counted.


n heptane belongs to the family of Acyclic Alkanes.
These are acyclic hydrocarbons consisting only of n carbon atoms and m hydrogen atoms where m=2*n + 2.
Introducing n-heptane, the magic potion of the solvent world!
This colorless, liquid hydrocarbon is the perfect solution for all your solvent needs.


n heptane is sure to add some excitement to your botanical extraction experiments.
But don't let its fun-loving scent fool you, n-heptane is a serious business.
Its seven carbon atoms and sixteen hydrogen atoms make n heptane a straight-chain alkane and a member of the prestigious heptane family.
n-heptane is the straight-chain alkane with the chemical formula H3C(CH2)5CH3 or C7H16.


When used as a test fuel component in anti-knock test engines, a 100% n heptane fuel is the zero point of the octane rating scale (the 100 point is a 100% iso-octane).
Octane number equates to the anti-knock qualities of a comparison mixture of n heptane and isooctane which is expressed as the percentage of isooctane in n heptane and is listed on pumps for gasoline dispensed in the United States and internationally.


n-Heptane is almost insoluble in water, but shows very good solubility or unlimited miscibility with many organic solvents such as ethanol, ethers, esters, white spirit, benzene or chlorinated hydrocarbons.
The RON (Research Octane Number) of n-heptane is by definition = 0.
n heptane is non-polar solvent.


n heptane is a clear colorless liquid with a petroleum odor like gasoline.
n heptane has a colorless liquid with a mild, Gasoline-like odor.
n heptane is the straight-chain alkane with the chemical formula H₃C(CH₂)₅CH₃ or C₇H₁₆, and is one of the main components of gasoline.
When used as a test fuel component in anti-knock test engines, a 100% n heptane fuel is the zero point of the octane rating scale.


Octane number equates to the anti-knock qualities of a comparison mixture of n heptane and isooctane which is expressed as the percentage of isooctane in heptane and is listed on pumps for gasoline dispensed globally.
n heptane was originally chosen as the zero point of the scale because of the availability of very high purity n heptane, unmixed with other isomers of n heptane or other alkanes, distilled from the resin of Jeffrey pine and from the fruit of Pittosporum resiniferum.


As a liquid, n heptane is ideal for transport and storage.
The 2,2-dimethylpentane isomer can be prepared by reacting tert-butyl chloride with n-propyl magnesium bromide.
The linear n heptane can be obtained from Jeffrey pine oil.
In water, both bromine and iodine appear brown.


n heptane is the straight-chain alkane with the chemical formula H3C(CH2)5CH3 or C7H16.
n heptane, also known as heptan or CH3-[CH2]5-CH3, belongs to the class of organic compounds known as alkanes.
These are acyclic branched or unbranched hydrocarbons having the general formula CnH2n+2 , and therefore consisting entirely of hydrogen atoms and saturated carbon atoms.


Thus, n heptane is considered to be a hydrocarbon lipid molecule.
n heptane is a very hydrophobic molecule, practically insoluble in water, and relatively neutral.
n heptane is a sweet, alkane, and ethereal tasting compound.
n heptane is the straight-chain alkane with the chemical formula H3C(CH2)5CH3 or C7H16.


When used as a test fuel component in anti-knock test engines, a 100% heptane fuel is the zero point of the octane rating scale (the 100 point is a 100% iso-octane).
Octane number equates to the anti-knock qualities of a comparison mixture of n heptane and isooctane which is expressed as the percentage of isooctane n heptane and is listed on pumps for gasoline dispensed in the United States and internationally.


n heptane (and its many isomers) is widely applied in laboratories as a totally non-polar solvent.
As a liquid, n heptane is ideal for transport and storage.
Aqueous bromine may be distinguished from aqueous iodine by its appearance after extraction into n heptane.
In water, both bromine and iodine appear brown.


However, iodine turns purple when dissolved in n heptane, whereas the bromine solution remains brown.
Because n heptane is nonpolar it is a good solvent for extraction.
n heptane (C7H16) is a colorless liquid that is insoluble in water.
n heptane is obtained by fractional distillation of petroleum.


n heptane’s boiling point is around 209°F, so it is important to properly purge the n heptane before consumption.
When processing plant material the first step is to dry n heptane out and then soak it in the solvent until it dissolves.
Then the extract can be collected from the solvent.
Next is the purging process, because hexane is not pressurized the purging process may take longer than using ethanol denatured with hexane.


But using n heptane as a solvent has its benefits.
n heptane creates a more potent and flavorful botanical oil.
Since n heptane is a pure, single-molecule product, it functions well for crystallization thanks to its tighter control of the chemical properties.


n heptane has a boiling point of 195-208°F.
n heptane is a non-polar solvent, typically used during plant extraction or crystallization processes.
n heptane is a straight-chained alkane.
n heptane is the straight-chain alkane with the chemical formula H3C(CH2)5CH3 or C7H16.


When used as a test fuel component in anti-knock test engines, a 100% n heptane fuel is the zero point of the octane rating scale (the 100 point is a 100% iso-octane).
Octane number equates to the anti-knock qualities of a comparison mixture of n heptane and isooctane which is expressed as the percentage of isooctane in n heptane and is listed on pumps for gasoline dispensed in the United States and internationally.
n heptane is the straight-chain alkane with the chemical formula H3C(CH2)5CH3 or C7H16, and is one of the main components of gasoline (petrol).



USES and APPLICATIONS of N HEPTANE:
n heptane (and its many isomers) is widely used in laboratories as a non-polar solvent.
As a liquid, n heptane is ideal for transport and storage.
In the grease spot test, n heptane is used to dissolve an oil spot to show the previous presence of organic compounds on a stained paper.
This is done by shaking the stained paper in a n heptane solution for about half a minute.


n heptane is commercially available as mixed isomers for use in paints and coatings, as the rubber cement solvent "Bestine", the outdoor stove fuel "Powerfuel" by Primus, as pure n-heptane for research and development and pharmaceutical manufacturing and as a minor component of gasoline (petrol).
On average, gasoline is about 1% n heptane.


n heptane is also used as an adhesive remover by stamp collectors.
Since 1974, the United States Postal Service has issued self-adhesive stamps that some collectors find difficult to separate from envelopes via the traditional method of soaking in water.
n heptane-based products like Bestine, as well as limonene-based products, have become popular solvents for removing stamps more easily.


n heptane's boiling point of 98.4 degrees Celsius and flash point of -4 degrees Celsius make it the perfect choice for all your high-temperature, flammable needs.
But n-heptane isn't just a one-trick pony.
n heptane's also a great solvent for extracting and purifying other chemicals.


And with its ability to dissolve in many organic solvents, n-heptane is the go-to choice for all your solvent-based concoctions.
Like all alkanes (paraffins, saturated hydrocarbons), n-heptane is a very good solvent for non-polar substances, fats and oils.
Especially in the pharmaceutical industry, n heptane is used as an inert solvent, for purification, recrystallization and washing of active pharmaceutical ingredients (API).


Some synthetic rubbers such as polybutadiene are produced in solution.
Since n-heptane is chemically inert (it has no so-called functionality or functional group), it is an ideal solvent for this sensitive reaction.
Heavy greases or oils can be diluted with parafins such as n-heptane to facilitate application.
n heptane is also found as a component in paints, varnishes and adhesives.


n heptane has an octane number of 0, which has been defined internationally.
This makes high-purity n-heptane (min. 99.75 %) a primary reference fuel for determining the octane number of a gasoline in a specially built engine.
The extraction and purification of the currently popular natural substance CBD (cannabidiol) is mainly carried out with n-heptane.


n heptane is used as a solvent and sometimes in coatings.
n heptane is a purified grade of solvent that is certified to meet a particular use.
n heptane is used as an industrial solvent and in petroleum refining processes.
n heptane has been detected, but not quantified, in cardamoms and gingers.


This could make n heptane a potential biomarker for the consumption of these foods.
This is done by shaking the stained paper in a n heptane solution for about half a minute.
n heptane is mainly used as a standard for the determination of octane number, but also can be used as anesthetics, solvents and raw materials for organic synthesis, the preparation of experimental reagents


In the grease spot test, n heptane is used to dissolve the oil spot to show the previous presence of organic compounds on a stained paper.
This is done by shaking the stained paper in a n heptane solution for about half a minute.
n heptane is used as a solvent, as an anaesthetic and in organic synthesis.
n heptane is mainly used as a standard for the determination of octane number, can also be used as an anesthetic, solvent and organic synthesis raw materials, preparation of experimental reagents


n heptane is used to dissolve or remove waxes/lipids during the extraction process.
n heptane (and its many isomers) is widely used in laboratories as a non-polar solvent.
As a liquid, n heptane is ideal for transport and storage.
In the grease spot test, n heptane is used to dissolve an oil spot to show the previous presence of organic compounds on a stained paper.


The contaminant-free purity of n heptane is mainly used in food production as a safe, easily evaporated non-polar solvent, particularly in extracting oils from seeds.
This n heptane is of a chemical grade with highest purity and meets or exceeds purity standards set by the American Chemical Society (ACS).
n heptane (and its many isomers) is widely used in laboratories as a non-polar solvent.
In the grease spot test, n heptane is used to dissolve an oil spot to show the previous presence of organic compounds on a stained paper.


Often times n heptane is used for certain types of extractions replacing the more toxic solvent hexane.
n heptane can be used to extract crude oil from the herb instead of more polar alcohols.
n heptane is also commonly employed as a solvent in liquid column chromatography.
When separating (fractionating) cannabis, the terpenes, other cannabinoids, and finally the plant material comes apart into layers that can be individually collected.


-Consumer & Industrial Applications of n heptane:
*Electronics:
Recognized as a leader in specialty chemicals, we are committed to providing and developing new and more efficient products, such as n-Heptane, Pure Grade, in the electronics industry, particularly in the rapidly growing technology sector.


-Applications of n heptane:
*Additives
*Electronics
*Solvents



PREPARATION of N HEPTANE:
The linear n-heptane can be obtained from Jeffrey pine oil.
The six branched isomers without a quaternary carbon can be prepared by creating a suitable secondary or tertiary alcohol by the Grignard reaction, converting it to an alkene by dehydration, and hydrogenating the latter.
The 2,2-dimethylpentane isomer can be prepared by reacting tert-butyl chloride with n-propyl magnesium bromide.
The 3,3-dimethylpentane isomer can be prepared from tert-amyl chloride and ethyl magnesium bromide.



ISOMERS AND ENANTIOMERS of N HEPTANE:
Heptane has nine isomers, or eleven if enantiomers are counted:
Heptane (n-heptane), H3C–CH2–CH2–CH2–CH2–CH2–CH3,
2-Methylhexane (isoheptane), H3C–CH(CH3)–CH2–CH2–CH2–CH3,
3-Methylhexane, H3C–CH2–C*H(CH3)–CH2–CH2–CH3 (chiral),

2,2-Dimethylpentane (neoheptane), H3C–C(CH3)2–CH2–CH2–CH3,
2,3-Dimethylpentane, H3C–CH(CH3)–C*H(CH3)–CH2–CH3 (chiral),
2,4-Dimethylpentane, H3C–CH(CH3)–CH2–CH(CH3)–CH3,

3,3-Dimethylpentane, H3C–CH2–C(CH3)2–CH2–CH3,
3-Ethylpentane, H3C–CH2–CH(CH2CH3)–CH2–CH3,
2,2,3-Trimethylbutane, H3C–C(CH3)2–CH(CH3)–CH3, this isomer is also known as pentamethylethane and triptane.



OCTANE RATING SCALE:
n-Heptane is defined as the zero point of the octane rating scale.
n heptane is a lighter component in gasoline, burns more explosively, causing engine pre-ignition (knocking) in its pure form, as opposed to octane isomers, which burn more slowly and give less knocking.
n heptane was originally chosen as the zero point of the scale because of the availability of very high purity n-heptane, unmixed with other isomers of heptane or other alkanes, distilled from the resin of Jeffrey pine and from the fruit of Pittosporum resiniferum.

Other sources of n heptane and octane, produced from crude oil, contain a mixture of different isomers with greatly differing ratings, and do not give as precise a zero point.
n heptane and Heptane”s”:
Heptanes are a mixture of several isomeric chains, of which, ≥25% is n-heptane.
n heptane is straight chain isomer of 100% heptane.



SUBSTITUENTS of N HEPTANE:
*Acyclic alkane
*Alkane
*Aliphatic acyclic compound



COMPOUND TYPE:
*Gasoline Additive/Component
*Industrial/Workplace Toxin
*Metabolite
*Natural Compound
*Organic Compound
*Solvent



WHY WOULD ONE NEED SOMETHING SO PURE AS N HEPTANE?
Generally, pure n heptane is only necessary in pharmaceutical and scientific laboratories.
Those industries require precise identification of chemicals and rigid control of all chemical variables.
For artists, architects and home crafters, regular Heptanes are more than adequate for cleaning up inks and rubber cements.
You could make an argument n heptane might be suitable for very expensive or high-tech commercial projects, but one would assume that the budgets for those projects would allow for higher priced materials.
All projects are unique in their own way and each user should always do a thorough job of investigating the best material to use.
But if the project does not qualify for one of the higher tier categories described in this article, it would make sense to make the budget conscious choice of choosing the lower cost Heptanes instead of n heptane.



PHYSICAL and CHEMICAL PROPERTIES of N HEPTANE:
Heat capacity (C): 224.64 J K−1 mol−1
Std molar entropy (S⦵298): 328.57 J K−1 mol−1
Std enthalpy of formation (ΔfH⦵298): −225.2 – −223.6 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): −4.8
Chemical formula: C7H16
Molar mass: 100.205 g·mol−1
Appearance: Colourless liquid
Odor: Petrolic
Density: 0.6795 g cm−3
Melting point: −90.549 °C (−130.988 °F; 182.601 K)

Boiling point: 98.38 °C (209.08 °F; 371.53 K)
Solubility in water: 0.0003% (20 °C)
log P: 4.274
Vapor pressure: 5.33 kPa (at 20.0 °C)
Henry's law constant (kH): 12 nmol Pa−1 kg−1
Magnetic susceptibility (χ): −85.24·10−6 cm3/mol
Refractive index (nD): 1.3855
Viscosity: 0.389 mPa·s
Dipole moment: 0.0 D
Formula Weight: 100.2g/mol
Physical Form: Liquid

Packaging: Amber glass bottle
Vapor Pressure: 48mbar at 20°C
Viscosity: 0.4 mPaS at 20°C
Vapor Density: 3.5
Melting Point: -91°C
Boiling Point: 98°C
Color: Colorless
Appearance (Clarity): Clear
Appearance (Colour): Colourless
Appearance (Form): Liquid
Colour (APHA): max. 10

Assay (GC): min. 99%
Density (g/ml) @ 20°C: 0.683-0.684
Refractive Index (20°C): 1.387-1.388
Boiling Range: 98-99°C
Non Volatile Matter: max. 0.001%
Acidity (CH3COOH): max. 0.0005%
Substance Discoloured by H2SO4: Passes
Iron (Fe): max. 0.00001%
Heavy Metals (Pb): max. 0.00001%
Sulphur Compound (S): max. 0.005%
Water (KF): max. 0.02%
Hill Formula: C 7 H 1 6
Chemical formula: CH 3 (CH 2 ) 5 CH 3

EC number: 205-563-8
molar mass: 100.2 g/mol
CAS number: 142-82-5
Ignition temperature: 215 °C
Solubility: 0.05 g/l (20 °C)
Melting point: -90.5 °C
Density: 0.68 g/cm3 ( 20 °C)
Boiling point: 97 - 98 °C (1013 hPa)
steam pressure: 48 hPa (20 °C)
Explosion limit: 1 - 7 %(V)
flash point: -4 °C
Refractive index: 1.3876

Molecular Weight: 100.20
XLogP3: 4.4
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 0
Rotatable Bond Count: 4
Exact Mass: 100.125200510
Monoisotopic Mass: 100.125200510
Topological Polar Surface Area: 0 Ų
Heavy Atom Count: 7
Formal Charge: 0
Complexity: 19.2

Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Appearance Form: liquid
Odor: No data available

Odor Threshold: No data available
pH: No data available
Melting point/freezing point Melting point: -91,0 °C
Initial boiling point and boiling range: 98,2 - 98,4 °C at 1.000 hPa
Flash point: -4 °C - c.c.
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper explosion limit: 7 %(V)
Lower explosion limit: 1,1 %(V)
Vapor pressure: 48 hPa at 20,0 °C
Vapor density: No data available

Density: 0,68 g/cm3 at 15 °C
Relative density: No data available
Water solubility: insoluble
Partition coefficient: n-octanol/water log Pow: > 3
Autoignition temperature: 223,0 °C
Decomposition temperature: No data available
Viscosity Viscosity, kinematic: 0,64 mm2/s at 20 °C
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: none

Other safety information: No data available
Boiling point: 97 - 98 °C (1013 hPa)
Density: 0.68 g/cm3 (15 °C)
Explosion limit: 1 - 7 %(V)
Flash point: -4 °C
Ignition temperature: 215 °C
Melting Point: -91.0 °C
Vapor pressure: 48 hPa (20.0 °C)
Solubility: 0.05 g/l

appearance: colorless volatile liquid
relative vapor density (Air = 1): 3.45
saturated vapor pressure (KPa): 5.33(22.3 ℃)
combustion heat (kj/mol): 4806.6
critical temperature (℃): 201.7
critical pressure (MPa): 1.62
ignition temperature (℃): 204
Upper Explosive limit%(V/V): 6.7
lower explosive limit%(V/V): 1.1



FIRST AID MEASURES of N HEPTANE:
-After inhalation:
Fresh air.
Call in physician.
-In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
-After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
-After swallowing:
Keep airways free.
Call a physician immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of N HEPTANE:
-Environmental precautions
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Dispose of properly.



FIRE FIGHTING MEASURES of N HEPTANE:
-Extinguishing media:
*Suitable extinguishing media:
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of N HEPTANE:
-Control parameters:
*Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses.
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,2 mm
Break through time: 60 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of N HEPTANE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Store at Room Temperature.



STABILITY and REACTIVITY of N HEPTANE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



SYNONYMS:
HEPTANE
n-Heptane
142-82-5
Heptan
Heptyl hydride
Dipropyl methane
Dipropylmethane
Gettysolve-C
Skellysolve C
Heptanen
Eptani
Pentane, ethyl-
NSC 62784
Heptene, homopolymer
Heptane (GC grade)
MFCD00009544
CHEBI:43098
456148SDMJ
NSC-62784
67290-43-1
HP6
HSDB 90
PETROLEUM ETHER
EINECS 205-563-8
UN1206
Heptanes
normal heptane
UNII-456148SDMJ
heptan-e
AI3-28784
2ygu
high purity heptane
pharma grade heptane
Heptane, for HPLC
Heptane 96%
n-Heptane, anhydrous
industry grade heptane
n-Heptane, 99%
n-Heptane HPLC grade
HPLC Grade n-Heptane
n-Heptane Reagent Grade
n-Heptane, HPLC grade
Heptane, 99.5%
Heptane, technical grade
HEPTANE [II]
N-HEPTANE [MI]
DSSTox_CID_4127
HEPTANE [USP-RS]
Ligroine, Heptane 100%
Heptane, anhydrous, 99%
UN 1206 (Related)
EC 205-563-8
Exxsol heptane (Salt/Mix)
Heptane, p.a., 95%
pharmaceutical grade heptane
Heptane, Laboratory Reagent
Heptane, analytical standard
DSSTox_RID_77301DSSTox_GSID_24127
Heptane, AR, >=99%
Heptane, LR, >=99%
Heptane-1,1,1-triylradical
WLN: 7H
Heptane, ASTM, 99.8%
n-C7H16
Heptane, p.a., 95.0%
n-Heptane, Environmental Grade
CHEMBL134658
DTXSID6024127
Heptane, for HPLC, >=96%
Heptane, for HPLC, >=99%
Heptane, HPLC grade, >=99%
Heptane, ReagentPlus(R), 99%
Heptane, purification grade, 99%
Heptane, >=99% (capillary GC)
Heptane, biotech. grade, >=99%
Heptanes (30-40 % n-heptane)
AMY22304
Heptane, for HPLC, >=99.5%
n-Heptane, Spectrophotometric Grade
NSC62784
ZINC1691363Tox21_201213
Heptane, puriss., >=99% (GC)LMFA11000575
AKOS009158011
Heptane, p.a., 88.0-92.0%
Heptane, UV HPLC spectroscopic, 95%
Heptane, SAJ first grade, >=98.0%
Heptane, spectrophotometric grade, 99%
Heptane, SAJ special grade, >=99.0%
NCGC00248959-01
NCGC00258765-01
CAS-142-82-5
Heptane, UV HPLC spectroscopic, 99.5%
Heptanes [UN1206] [Flammable liquid
LS-13366
n-Heptane 100 microg/mL in Acetonitrile
FT-0659788
H0027
H0088
H0491
Heptane, puriss. p.a., >=99.5% (GC)
Q0037
Heptane (mixture of isomers) ~12 % n-heptane
A807968
Heptane, for preparative HPLC, >=99.7% (GC)
Q310957
Heptane, B&J Brand (product of Burdick & Jackson)
Heptane, UV HPLC spectroscopic, mixture of isomersJ-007700
n-Heptane HPLC, UV-IR min. 99%, isocratic grade
F1908-0180
B7F4D751-FB0E-4F48-9829-D952CEC36530
Heptane
Heptane, Pharmaceutical Secondary Standard; Certified Reference Material
Heptane, PRA grade, 96% n-isomer basis, >=99.9% C7 isomers basis
Heptane, puriss. p.a., Reag. Ph. Eur., >=99% n-heptane basis (GC)
Heptane Fraction, puriss. p.a., Reag. Ph. Eur., >=99% n-heptane basis (GC)
Heptane, puriss., absolute, over molecular sieve (H2O <=0.005%), >=99.5% (GC)
alkane C7
ASTM normal-heptane knock test reference fuel
dipropylmethane
dipropylmethane (=normal-heptane)
ESSO heptane
gettysolve-C
heptane, anhydrous
Heptanes
heptyl hydride
hexylmethane
HYDROSOL-HEPTANE
methylhexane
ndipropylmethane
n-heptane
n-heptyl hydride
normal-dipropylmethane
normal-heptane
normal-heptyl hydride
NORPAR 7
protein sequencer reagent S1
SBP 94/99
skellysolve C
solvent heptane
Heptane
n-Heptane
Heptyl hydride
Dipropylmethane
n-Heptane
Normal heptane




N HEPTANE
N-heptane is a colorless liquid with a characteristic hydrocarbon odor.
N-heptane is highly flammable and evaporates quickly at room temperature.
N-heptane is a flammable, volatile, organic, straight-chain alkane of seven carbon atoms.

CAS Number: 142-82-5
Molecular Formula: C7H16
Molecular Weight: 100.2
EINECS: 205-563-8

Due to its low octane rating, N-heptane is commonly used as a reference standard for octane ratings in gasoline (usually assigned an octane rating of zero).
Available in a range of quantities, purities, and reagent grades, heptane is a commonly used non-polar solvent and a key component in gasoline.
N-heptane is a flammable liquid, present in crude oil and widely used in the auto- mobile industry.

N-heptane causes adverse health effects in occupational workers, such as CNS depression, skin irritation, and pain.
Other compounds such as n-octane (CH 3 (CH 2 ) 6 CH 3 ), n-nonane (CH 3 (CH 2 ) 7 CH 3 ), and n-decane (CH 3 (CH 2 ) 8 CH 3 ) have different industrial applications.
Occupational workers exposed to these compounds also show adverse health effects.

In principle, manage- ment of these aliphatic compounds requires proper handling and disposal to avoid health problems and to maintain chemical safety standards for safety to workers and the living environment.
N-heptane is produced in refining processes. Highly purified heptane is produced by adsorption of commercial heptane on molecular sieves.

N-heptane, clear, colorless, very flammable liquid with a faint, pleasant odor resembling hexane or octane.
Based on a triangle bag odor method, an odor threshold concentration of 670 ppbv was reported by Nagata and Takeuchi (1990).

N-heptane is an aliphatic alkane with the molecular formula C7H16.
Naturally occurring N-heptane is isolated from natural gas, crude oil, or pine extracts.

N-heptane is the straight-chain alkane with the chemical formula H3C(CH2)5CH3 or C7H16. When used as a test fuel component in anti-knock test engines, a 100% heptane fuel is the zero point of the octane rating scale (the 100 point is 100% iso-octane). Octane number equates to the anti-knock qualities of a comparison mixture of heptane and isooctane which is expressed as the percentage of isooctane in heptane and is listed on pumps for gasoline (petrol) dispensed globally.

N-heptane is one of the three isomers of heptane.
The other two isomers are 2-methylhexane (also known as isoheptane) and 3-methylhexane (also known as neoheptane).
These isomers have different molecular structures and physical properties, such as boiling points and densities.

N-heptane is assigned an octane rating of zero in the octane rating scale used to measure the performance of gasoline.
This is because it has a high tendency to knock or pre-ignite in an engine, leading to poor engine performance.
On the other hand, isoheptane and neoheptane have higher octane ratings and are used as reference compounds with octane ratings of 100 and 105, respectively.

N-heptane is often used as a reference substance in thermodynamic studies and for calibrating calorimeters.
N-heptanes enthalpy of combustion is taken as a standard reference value for defining the heat of combustion for other substances.

N-heptane is a volatile organic compound (VOC) and can contribute to air pollution when released into the atmosphere.
It is important to handle and store N-heptane responsibly to minimize its environmental impact.
N-heptane finds applications in various industrial processes, such as extracting oils and waxes from seeds, as a component in some industrial coatings and adhesives, and as a cleaning solvent in certain manufacturing processes.

When handling N-heptane, it is essential to work in well-ventilated areas to prevent the accumulation of vapors.
N-heptane should be stored in tightly closed containers away from sources of heat and ignition.
N-heptane may be subject to specific regulations depending on its use and the jurisdiction in which it is utilized.

N-heptane is a chain-like hydrocarbon from the alkane group with the chemical formula C7H16.
It is the unbranched representative and technically the most important of the nine heptane isomers.

Melting point: −91 °C(lit.)
Boiling point: 98 °C(lit.)
Density: 0.684 g/mL at 20 °C
vapor density: 3.5 (vs air)
vapor pressure: 40 mm Hg ( 20 °C)
refractive index: n20/D 1.397
Flash point: 30 °F
storage temp.: Store at +5°C to +30°C.
solubility acetone: miscible(lit.)
form: Liquid
pka: >14 (Schwarzenbach et al., 1993)
Specific Gravity: 0.684 (20/4℃)
color: ≤10(APHA)
Relative polarity: 0.012
Odor:Gasoline.
Odor Threshold: 0.67ppm
Evaporation Rate: 2.8
explosive limit: 1-7%(V)
Water Solubility: practically insoluble
λmax λ: 200 nm Amax: ≤1.0
λ: 225 nm Amax: ≤0.10
λ: 250 nm Amax: ≤0.01
λ: 300-400 nm Amax: ≤0.005
Merck:14,4659
BRN: 1730763
LogP: 4.660

N-heptane is the straight-chain alkane with the chemical formula H3C(CH2)5CH3 or C7H16.
When used as a test fuel component in anti-knock test engines, a 100% N-heptane fuel is the zero point of the octane rating scale (the 100 point is a 100% iso-octane).
Octane number equates to the anti-knock qualities of a comparison mixture of N-heptane and isooctane which is expressed as the percentage of isooctane in heptane and is listed on pumps for gasoline dispensed in the United States and internationally.

N-heptane (and its many isomers) is widely applied in laboratories as a totally non-polar solvent.
As a liquid, N-heptane is ideal for transport and storage.

In the grease spot test, N-heptane is used to dissolve the oil spot to show the previous presence of organic compounds on a stained paper.
This is done by shaking the stained paper in a heptane solution for about half a minute.

N-heptane is produced from crude oil through precision refining and distillation that is used in the measurement of octane rating for fuels.
It is also used for the purification of pharmaceutical products and other synthetic organics.
The flash point of N-heptane is approximately -4°C to -20°C (25°F to -4°F).

The autoignition temperature of N-heptane is approximately 215°C to 225°C (419°F to 437°F).
The autoignition temperature is the minimum temperature at which a substance will spontaneously ignite without an external ignition source, such as an open flame.
N-heptane has a relatively low vapor pressure at room temperature, which means it does not readily evaporate into the air at normal atmospheric conditions.

N-heptane is considered to be readily biodegradable.
This means that under appropriate environmental conditions, microorganisms can break down N-heptane into simpler and less harmful substances.
Due to its flammability and health hazards, N-heptane is sometimes replaced with safer solvents in specific applications.

Solvent substitution is a common approach to reduce health and environmental risks associated with chemical use.
N-heptane is often used in educational settings, especially in organic chemistry laboratories, for various experiments and demonstrations.
It serves as a convenient and relatively safe solvent for many organic reactions.

Uses
N-heptane (and its many isomers) is widely used in laboratories as a non-polar solvent.
N-heptane is used to dissolve an oil spot to show the previous presence of organic compounds on a stained paper.
This is done by shaking the stained paper in a heptane solution for about half a minute.

N-heptane is frequently used as a non-polar solvent in laboratories, especially for applications where water or polar solvents are not suitable.
N-heptane is used in various extraction processes to dissolve non-polar compounds or separate different components in mixtures.
N-heptane is employed as a cleaning agent for equipment and machinery in industries where non-polar solvent cleaning is required.

N-heptane can be used as a fuel additive, although its low octane rating limits its practical use as a gasoline component.
N-heptane is utilized as a reference compound in gas chromatography and other analytical techniques.
Aqueous bromine may be distinguished from aqueous iodine by its appearance after extraction into N-heptane.

N-heptane is commercially available as mixed isomers for use in paints and coatings, as the rubber cement solvent "Bestine", the outdoor stove fuel "Powerfuel" by Primus, pure. N-heptane for research and development and pharmaceutical manufacturing and as a minor component of gasoline (petrol).
N-heptane is also used as an adhesive remover by stamp collectors.

N-heptane serves as a non-polar solvent in laboratories for dissolving non-polar compounds, extracting oils from seeds, and performing various organic chemistry experiments.
N-heptane is used as a cleaning solvent in industrial and commercial applications, such as degreasing equipment and machinery, removing oil and grease stains, and cleaning certain types of surfaces.

N-heptane is used as a reference compound in gas chromatography and other analytical techniques.
Its elution time and behavior are well-established, making it a benchmark for identifying and characterizing other compounds in a mixture.

N-heptane can be used as a solvent in paint formulations and coatings to achieve the desired consistency and viscosity.
However, its use in consumer products is limited due to its flammability and health concerns.
In some cases, N-heptane may be added as a blending component for fuels.

N-heptane finds applications in various research and development activities, such as in chemical synthesis, process optimization, and experimental studies.
N-heptane can be used in the production of certain adhesives and glues.
N-heptane can be used as a reagent or starting material in chemical synthesis for the preparation of other compounds.

N-heptane is employed in organic extractions to separate or isolate specific components from a mixture based on their solubility properties.
N-heptane is used in the following products: coating products, pH regulators and water treatment products, laboratory chemicals, adhesives and sealants, polymers, water treatment chemicals and oil and gas exploration or production products.

N-heptane is used for the manufacture of: chemicals and machinery and vehicles.
Release to the environment of N-heptane can occur from industrial use: in processing aids at industrial sites, of substances in closed systems with minimal release, formulation of mixtures, manufacturing of the substance, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, as processing aid, for thermoplastic manufacture and formulation in materials.

N-heptane is used in the rubber industry as a processing aid and softener for rubber compounds.
It helps improve the flow properties during the manufacturing process and facilitates the mixing of rubber ingredients.
N-heptane is used in the printing industry as a solvent for cleaning printing equipment, such as rollers and ink trays.

N-heptane is used in pharmaceutical and chemical industries for various purposes, such as in the production of drugs, chemicals, and intermediates.
N-heptane is sometimes used as a calibration fluid in analytical instruments, particularly in gas chromatography, to calibrate and validate the instrument's performance.

N-heptane is used in gasoline testing to determine the octane rating of gasoline blends.
It is used as a reference compound to calibrate the octane rating scale.
N-heptane is used in the preparation of calibration gas mixtures used in gas analyzers and detectors for monitoring air quality or measuring specific gas concentrations.

N-heptane can be used as a solvent in the production of rubber cement, an adhesive used for bonding rubber to various substrates.
N-heptane may be used in the formulation of certain agricultural chemicals and pesticides.
N-heptane can be used in the textile industry for applications such as dyeing and printing processes.

In some cases, N-heptane is used in the oil and gas industry as a carrier fluid or diluent in certain processes.
N-heptane can be used in metal cleaning applications, particularly for removing oils and contaminants from metal surfaces.

Safety Precautions
N-heptane is flammable and should be handled with care.
It should be stored in well-ventilated areas away from open flames or potential sources of ignition.
Additionally, exposure to high concentrations of N-heptane vapors in poorly ventilated areas should be avoided to prevent health risks.

Health Hazards
Prolonged or repeated exposure to N-heptane vapors may cause irritation of the respiratory tract and skin.
Inhalation of high concentrations of N-heptane vapor can lead to headaches, dizziness, and nausea.
The Occupational Safety and Health Administration (OSHA) and other regulatory agencies have set exposure limits to protect workers from potential health hazards.

Environmental Impact
While N-heptane is considered to be readily biodegradable, it can still contribute to ground-level ozone formation when released into the atmosphere.
Ground-level ozone is a harmful air pollutant and a major component of smog.

Synonyms
HEPTANE
N-heptane
142-82-5
Heptan
Heptyl hydride
Dipropyl methane
Dipropylmethane
Gettysolve-C
Skellysolve C
Heptanen
Eptani
Pentane, ethyl-
Heptan [Polish]
Eptani [Italian]
Heptanen [Dutch]
HSDB 90
NSC 62784
Heptanes
normal-Heptane
EINECS 205-563-8
UNII-456148SDMJ
Heptane (GC grade)
DTXSID6024127
CHEBI:43098
AI3-28784
456148SDMJ
MFCD00009544
NSC-62784
UN1206
DTXCID004127
EC 205-563-8
HEPTANE (II)
HEPTANE [II]
HP6
heptano
normal heptane
heptan-e
2ygu
high purity heptane
pharma grade heptane
Heptane, for HPLC
Heptane 96%
N-heptane, anhydrous
Heptane (N-heptane)
industry grade heptane
N-heptane, 99%
N-heptane HPLC grade
HPLC Grade N-heptane
HPT (CHRIS Code)
N-heptane Reagent Grade
N-heptane, HPLC grade
HEPTANE [HSDB]
HEPTANE [INCI]
Heptane, 99.5%
Heptane, technical grade
HEPTANE (N)
N-heptane [MI]
HEPTANE [USP-RS]
Ligroine, Heptane 100%
Heptane, anhydrous, 99%
Exxsol heptane (Salt/Mix)
Heptane, p.a., 95%
pharmaceutical grade heptane
Heptane, Laboratory Reagent
Heptane, analytical standard
Heptane, AR, >=99%
Heptane, LR, >=99%
Heptane-1,1,1-triylradical
WLN: 7H
Heptane, ASTM, 99.8%
n-C7H16
Heptane, p.a., 95.0%
N-heptane, Environmental Grade
CHEMBL134658
Heptane, for HPLC, >=96%
Heptane, for HPLC, >=99%
CH3-(CH2)5-CH3
Heptane, HPLC grade, >=99%
Heptane, ReagentPlus(R), 99%
Heptane, purification grade, 99%
Heptane, >=99% (capillary GC)
Heptane, biotech. grade, >=99%
Heptanes (30-40 % N-heptane)
AMY22304
Heptane, for HPLC, >=99.5%
NSC62784
Tox21_201213
Heptane, puriss., >=99% (GC)
LMFA11000575
NA1206
AKOS009158011
Heptane, p.a., 88.0-92.0%
Heptane, UV HPLC spectroscopic, 95%
Heptane, SAJ first grade, >=98.0%
Heptane, spectrophotometric grade, 99%
Heptane, SAJ special grade, >=99.0%
Heptanes [UN1206] [Flammable liquid]
NCGC00248959-01
NCGC00258765-01
CAS-142-82-5
Heptane, UV HPLC spectroscopic, 99.5%
Heptanes [UN1206] [Flammable liquid]
LS-74295
N-heptane 100 microg/mL in Acetonitrile
FT-0659788
H0027
H0088
H0491
Heptane, puriss. p.a., >=99.5% (GC)
Q0037
A807968
Heptane, for preparative HPLC, >=99.7% (GC)
Q310957
J-007700
N-heptane HPLC, UV-IR min. 99%, isocratic grade
N-heptane, Spectrophotometric Grade, 99% n-Heptan
F1908-0180
B7F4D751-FB0E-4F48-9829-D952CEC36530
Heptane, United States Pharmacopeia (USP) Reference Standard
InChI=1/C7H16/c1-3-5-7-6-4-2/h3-7H2,1-2H
Heptane, Pharmaceutical Secondary Standard; Certified Reference Material
Heptane, PRA grade, 96% n-isomer basis, >=99.9% C7 isomers basis
Heptane, puriss. p.a., Reag. Ph. Eur., >=99% N-heptane basis (GC)
Heptane Fraction, puriss. p.a., Reag. Ph. Eur., >=99% N-heptane basis (GC)
Heptane, puriss., absolute, over molecular sieve (H2O <=0.005%), >=99.5% (GC)

N HEPTANE
N-​(3-​Aminopropyl)​-​n-​dodecylpropane-​1,​3-​diamine; DPTA-Y12D;Lonzabac 12;DPTA-Y12D-30;Triameen Y 12;Triameen Y12D;LONZABAC12.100;methylenediamine;Lonzabac(R) 12.30;Lonzabac(R) 12.100;Bis(aminopropyl)laurylamine cas no: 2372-82-9
N N Dimethyl amine
m-Xylene-alpha,alpha-diamine; m-Xylylenediamine; m-Xylene-alpha,alpha-diamine; MXDA; 1,3-Benzenedimethanamine; pXDA; m-Xylene micron-micron-diamine; alpha,alpha-m-Xylenediamine; alpha,alpha-Diamino-m-xylene; m-Diaminoxylene; m-Xylylendiamin; 1,3-Bis(aminomethyl)benzene; m-Phenylenebis(methylamine); m-Xylylene amine; Methylamine, m-phenylenebis-; meta-Xylenediamine CAS NO: 1477-55-0
N-​(3-​Aminopropyl)​-​n-​dodecylpropane-​1,​3-​diamine
2-(2-Aminoethylamino)-Ethanol; N-hydroxyethyl-1,2-ethanediamine; N-hydroxyethylethylenediamine; N-(2-Hydroxyethyl)ethylenediamine; 2-((aminoethyl)amino)ethanol; N-aminoethylethanolamine; cas no: 111-41-1
N-(2-Aminoethyl)-3-Aminopropyltrimethoxysilane
SYNONYMS n-Tetradecoic acid; 1-Tridecanecarboxylic acid; n-Tetradecanoic acid; Crodacid; Hydrofol acid 1495; n-Tetradecan-1-oic acid; CAS NO. 544-63-8
N, N-DIMETHYLUREA (1,3-DIMETHYLUREA)

N, n-dimethylurea (1,3-dimethylurea) is a chemical compound with the molecular formula C4H8N2O.
N, n-dimethylurea (1,3-dimethylurea) belongs to the class of compounds known as ureas, characterized by the presence of the urea functional group.
N, n-dimethylurea (1,3-dimethylurea) features two methyl groups attached to separate nitrogen atoms within the urea structure.
Its molecular structure consists of a central urea moiety with two methyl substituents.

CAS Number: 96-31-1
EC Number: 202-498-7



APPLICATIONS


N, n-dimethylurea (1,3-dimethylurea) may find application as a reagent in the synthesis of complex organic molecules.
Its chemical structure could contribute to the design of nitrogen-rich polymers with specific properties.

In certain catalytic processes, N, n-dimethylurea (1,3-dimethylurea) might serve as a substrate or ligand.
N, n-dimethylurea (1,3-dimethylurea)'s solubility characteristics could be advantageous in specific solvent systems.
N, n-dimethylurea (1,3-dimethylurea) may be explored for its potential as a building block in pharmaceutical research.

Its participation in hydrogen bonding interactions may be of interest in supramolecular chemistry studies.
N, n-dimethylurea (1,3-dimethylurea) might have applications in the development of specialty coatings or adhesives.
In agricultural research, N, n-dimethylurea (1,3-dimethylurea) could be investigated for its effects on plant growth or as a potential fertilizer component.

The unique reactivity of N, n-dimethylurea (1,3-dimethylurea) might make it suitable for certain polymerization reactions.
Research into its behavior under different temperature and pressure conditions may reveal new applications.
N, n-dimethylurea (1,3-dimethylurea) could be explored as a potential precursor in the synthesis of heterocyclic compounds.
Its presence in reaction mixtures may impact the selectivity of certain chemical transformations.

In the field of materials science, N, n-dimethylurea (1,3-dimethylurea) might be incorporated into the design of novel materials.
Researchers might investigate its use in the development of specialty resins or coatings.
N, n-dimethylurea (1,3-dimethylurea) could be evaluated for its role in catalyzing specific chemical reactions.

N, n-dimethylurea (1,3-dimethylurea)'s potential to form complexes with metal ions may be explored in coordination chemistry studies.
Its stability under certain conditions could make it suitable for inclusion in specific formulations.
In medicinal chemistry, N, n-dimethylurea (1,3-dimethylurea) may be examined for potential pharmacological properties.

N, n-dimethylurea (1,3-dimethylurea)'s solubility characteristics might be advantageous in the formulation of certain pharmaceutical products.
N, n-dimethylurea (1,3-dimethylurea) may be studied for its potential as a flame retardant in certain materials.
In the realm of environmental chemistry, its behavior in aqueous systems could be investigated.
Its use in specialty chemical processes may be explored for the development of new materials.

Researchers might assess its impact on reaction kinetics and product distribution in various chemical reactions.
N, n-dimethylurea (1,3-dimethylurea)'s potential as a reagent in asymmetric synthesis could be of interest in organic chemistry.
Its interaction with specific enzymes or catalysts might be examined for potential biotechnological applications.

N, n-dimethylurea (1,3-dimethylurea)'s solubility properties may make it suitable for inclusion in certain formulations of specialty inks or dyes.
In the realm of nanotechnology, the compound might be investigated for its role in the synthesis of nanomaterials with unique properties.

Its potential as a stabilizing agent in the formulation of certain emulsions or dispersions could be explored in the cosmetic industry.
N, n-dimethylurea (1,3-dimethylurea) may be considered as a potential co-catalyst in certain chemical reactions to enhance reaction rates.

Its ability to form complexes with metal ions may find application in analytical chemistry for selective metal ion detection.
N, n-dimethylurea (1,3-dimethylurea) could be examined for its influence on the crystallization behavior of certain materials in materials science research.
Researchers might investigate N, n-dimethylurea (1,3-dimethylurea)'s behavior in ionic liquids for potential applications in green chemistry.
Its role as a potential building block in the design of supramolecular structures could be explored in molecular assembly studies.

N, n-dimethylurea (1,3-dimethylurea) may be assessed for its compatibility with specific polymers in the development of specialty polymer blends.
N, n-dimethylurea (1,3-dimethylurea)'s interaction with certain biomolecules could be investigated for applications in bioorganic chemistry.

In the field of medicinal chemistry, its potential as a ligand in the design of metallopharmaceuticals might be explored.
N, n-dimethylurea (1,3-dimethylurea) might be considered as a potential corrosion inhibitor in the formulation of specialty coatings.
N, n-dimethylurea (1,3-dimethylurea)'s stability under specific environmental conditions could find application in soil remediation processes.

Its behavior as a potential chelating agent may be studied for applications in wastewater treatment processes.
N, n-dimethylurea (1,3-dimethylurea)'s reactivity might be harnessed for its potential use in the synthesis of specialty fine chemicals.
N, n-dimethylurea (1,3-dimethylurea) could be evaluated for its impact on the rheological properties of certain formulations in the cosmetics industry.

In the development of smart materials, researchers might explore its responsiveness to external stimuli.
N, n-dimethylurea (1,3-dimethylurea) might be considered for its potential role as a template in the synthesis of porous materials.
N, n-dimethylurea (1,3-dimethylurea)'s use as a potential precursor in the synthesis of conducting polymers may be investigated.

Its presence in certain reaction mixtures may influence the regioselectivity of certain chemical reactions.
Researchers might explore its potential as a reducing agent in the synthesis of nanoparticles.
N, n-dimethylurea (1,3-dimethylurea)'s participation in certain organometallic reactions might be studied for applications in organometallic chemistry.

N, n-dimethylurea (1,3-dimethylurea)'s unique properties could be harnessed for applications in the development of specialty adhesives.
Its compatibility with specific organic compounds may find applications in the formulation of specialty lubricants.
N, n-dimethylurea (1,3-dimethylurea) might be investigated for its potential as a reagent in the synthesis of functionalized organic molecules for material science applications.

N, n-dimethylurea (1,3-dimethylurea)'s compatibility with certain resins may make it suitable for incorporation into specialty composite materials.
In the field of energy storage, N, n-dimethylurea (1,3-dimethylurea) could be explored for its potential use in the design of advanced battery electrolytes.
Its interaction with specific catalysts may open avenues for exploring its role in catalytic asymmetric reactions in organic synthesis.

N, n-dimethylurea (1,3-dimethylurea) might be studied for its potential as a template in the synthesis of zeolites with controlled porosity.
Its solubility characteristics could be advantageous in the formulation of certain types of agricultural chemicals or fertilizers.
N, n-dimethylurea (1,3-dimethylurea) may find application in the development of specialty lubricating oils due to its chemical stability.

Researchers might investigate its potential as a precursor in the synthesis of nitrogen-rich energetic materials.
N, n-dimethylurea (1,3-dimethylurea) could be explored for its use in the creation of controlled-release formulations in the pharmaceutical industry.
Its potential as a stabilizer in the formulation of certain polymer blends may be of interest in plastics manufacturing.

In the realm of water treatment, the compound might be considered for its chelating properties in metal ion removal processes.
N, n-dimethylurea (1,3-dimethylurea)'s behavior under specific temperature and pressure conditions could find applications in high-pressure chemistry.
Its potential to form inclusion complexes may be explored for applications in drug delivery systems.

N, n-dimethylurea (1,3-dimethylurea) might be studied for its impact on the rheological behavior of certain polymer solutions in the cosmetics industry.
N, n-dimethylurea (1,3-dimethylurea)'s interaction with specific transition metals could be investigated for potential catalytic applications.
Researchers might explore its potential as a corrosion inhibitor in the formulation of coatings for metal surfaces.
Its use as a potential intermediate in the synthesis of specialty surfactants may find applications in the detergent industry.

N, n-dimethylurea (1,3-dimethylurea) could be investigated for its potential role in the synthesis of nitrogen-doped carbon materials.
N, n-dimethylurea (1,3-dimethylurea)'s reactivity under controlled conditions might be harnessed for applications in organometallic chemistry.
Its ability to form complexes with certain guest molecules may be explored for gas storage applications.

N, n-dimethylurea (1,3-dimethylurea) might be studied for its potential as a stabilizing agent in the formulation of colloidal suspensions.
In the field of materials science, its role in the synthesis of metal-organic frameworks (MOFs) may be investigated.
N, n-dimethylurea (1,3-dimethylurea)'s participation in certain chemical reactions may be explored for applications in green chemistry.

Researchers might study its potential as a co-catalyst in the development of sustainable chemical processes.
N, n-dimethylurea (1,3-dimethylurea)'s reactivity toward specific functional groups could be explored for applications in organic synthesis.
N, n-dimethylurea (1,3-dimethylurea)'s unique properties might find applications in the creation of stimuli-responsive materials for advanced technologies.

N, n-dimethylurea (1,3-dimethylurea)'s potential role as a phase-transfer catalyst may find applications in facilitating reactions between immiscible phases.
In the realm of polymer science, N, n-dimethylurea (1,3-dimethylurea) might be explored for its influence on the crystallization behavior of polymeric materials.
Its compatibility with certain inorganic salts may make it suitable for use in the formulation of electrolytes for specific applications.

N, n-dimethylurea (1,3-dimethylurea) could be studied for its potential as a nitrogen source in the synthesis of nitrogen-doped carbon nanomaterials.
N, n-dimethylurea (1,3-dimethylurea)'s participation in specific redox reactions may open avenues for its use in electrochemical applications.
Researchers might explore its potential as a stabilizing agent in the formulation of nanoparticle dispersions for various applications.

In the field of sensors and detection, N, n-dimethylurea (1,3-dimethylurea)'s reactivity toward specific analytes might be harnessed for sensing applications.
Its potential role as a ligand in coordination chemistry may find applications in the design of novel metal complexes.

N, n-dimethylurea (1,3-dimethylurea) could be investigated for its impact on the viscosity of certain fluid systems in industrial processes.
N, n-dimethylurea (1,3-dimethylurea)'s solubility characteristics may be advantageous in the formulation of specialty inks for specific printing applications.
Its interaction with specific polymers might be explored for potential applications in the modification of polymer surfaces.
N, n-dimethylurea (1,3-dimethylurea)'s potential as a complexing agent for certain metal ions may be relevant in analytical chemistry applications.

N, n-dimethylurea (1,3-dimethylurea) could be studied for its potential use as a sacrificial reagent in specific chemical transformations.
In the realm of catalysis, N, n-dimethylurea (1,3-dimethylurea) might be considered as a co-catalyst in the development of asymmetric catalytic reactions.

Researchers might investigate its role as a precursor in the synthesis of heterocyclic compounds with unique properties.
N, n-dimethylurea (1,3-dimethylurea)'s potential as a template in the formation of metal-organic frameworks (MOFs) may have applications in gas storage.
N, n-dimethylurea (1,3-dimethylurea)'s compatibility with specific organic solvents could find applications in the design of novel solvent systems.

Its use as a potential reducing agent might be explored for applications in the synthesis of metal nanoparticles.
N, n-dimethylurea (1,3-dimethylurea)'s potential in the development of environmentally friendly processes may be relevant to green chemistry initiatives.
N, n-dimethylurea (1,3-dimethylurea)'s potential as a nitrogen source in the synthesis of specialty polymers might find applications in material science.
Researchers might explore its use in the formulation of controlled-release fertilizers for agricultural applications.

N, n-dimethylurea (1,3-dimethylurea)'s interaction with specific additives might be investigated for potential applications in the enhancement of lubricant properties.
Its compatibility with certain biodegradable polymers may make it suitable for use in environmentally friendly materials.
N, n-dimethylurea (1,3-dimethylurea) could be explored for its role in the synthesis of nitrogen-containing pharmaceutical intermediates.
N, n-dimethylurea (1,3-dimethylurea)'s participation in certain oxidation reactions may find applications in the development of oxidative coupling processes.



DESCRIPTION


N, n-dimethylurea (1,3-dimethylurea) is a chemical compound with the molecular formula C4H8N2O.
N, n-dimethylurea (1,3-dimethylurea) belongs to the class of compounds known as ureas, characterized by the presence of the urea functional group.
N, n-dimethylurea (1,3-dimethylurea) features two methyl groups attached to separate nitrogen atoms within the urea structure.
Its molecular structure consists of a central urea moiety with two methyl substituents.

N, n-dimethylurea (1,3-dimethylurea) has a linear molecular geometry, with the nitrogen atoms forming a bridge between the two methyl groups.
N, n-dimethylurea (1,3-dimethylurea) exhibits characteristics of both urea and methylated derivatives, influencing its reactivity and properties.

N, n-dimethylurea (1,3-dimethylurea) is colorless, and its physical state can vary depending on temperature and pressure conditions.
N, n-dimethylurea (1,3-dimethylurea) is synthesized through specific chemical reactions involving urea and methylating agents.
N, n-dimethylurea (1,3-dimethylurea) is used in various industrial applications, including as a reagent in chemical synthesis.
The presence of methyl groups enhances the compound's solubility in certain organic solvents.

N, n-dimethylurea (1,3-dimethylurea) may participate in hydrogen bonding interactions due to the presence of amide functional groups.
N, n-dimethylurea (1,3-dimethylurea) has specific applications in organic chemistry as a building block for the synthesis of more complex molecules.
Its molecular weight is approximately 100.12 grams per mole.

The chemical structure of N, N-dimethylurea imparts unique chemical and physical properties, influencing its behavior in reactions.
N, n-dimethylurea (1,3-dimethylurea) can act as a reactant in the preparation of various nitrogen-containing organic compounds.
N, n-dimethylurea (1,3-dimethylurea)'s stability and reactivity depend on environmental factors and reaction conditions.
N, n-dimethylurea (1,3-dimethylurea) may be subject to certain regulatory considerations due to its use in chemical processes.

Its presence in a reaction mixture can influence reaction kinetics and product distribution.
In certain contexts, N, n-dimethylurea (1,3-dimethylurea) may serve as a model compound for theoretical studies on molecular interactions.
N, n-dimethylurea (1,3-dimethylurea)'s chemical behavior can be explored in the context of hydrogen bonding and steric effects.

Researchers may study its behavior as a substrate in enzymatic or catalytic reactions.
N, n-dimethylurea (1,3-dimethylurea)'s chemical versatility contributes to its utility in various laboratory settings.
N, n-dimethylurea (1,3-dimethylurea) is important for researchers and chemists to consider the compound's properties when designing experiments.

The synthesis of N, n-dimethylurea (1,3-dimethylurea) can involve the use of specific catalysts and reaction conditions.
Understanding the reactivity and properties of N, n-dimethylurea (1,3-dimethylurea) is crucial for its effective utilization in chemical processes.



PROPERTIES


Physical Properties:

Molecular Formula: C4H8N2O
Molecular Weight: Approximately 100.12 g/mol
Appearance: Typically a colorless or white crystalline solid.
Melting Point: The melting point of N, N-dimethylurea is influenced by factors such as purity and crystalline form. It is generally reported in the range of 155-160°C.


Chemical Properties:

Solubility: The compound is usually soluble in polar solvents, including water and some organic solvents.
Reactivity:
Reactivity with Metals: N, N-dimethylurea may form complexes with certain metal ions, and its reactivity can be influenced by the presence of metal catalysts.
Hydrogen Bonding: The amide functional groups in the urea moiety may participate in hydrogen bonding interactions.



FIRST AID


Inhalation:

Move to Fresh Air:
If inhaled, move the affected person to an area with fresh air.
Ensure proper breathing.
If breathing difficulties persist, seek immediate medical attention.


Skin Contact:

Remove Contaminated Clothing:
Quickly and gently remove contaminated clothing, including shoes.

Wash Skin Thoroughly:
Wash the affected skin area thoroughly with mild soap and water.
Rinse for at least 15 minutes.

Seek Medical Attention:
If irritation, redness, or other symptoms persist, seek medical attention.


Eye Contact:

Rinse Eyes Immediately:
Immediately rinse the eyes with gently flowing lukewarm water.
Ensure thorough rinsing for at least 15 minutes, holding eyelids open.

Seek Medical Attention:
Seek immediate medical attention if irritation, redness, or pain persists.


Ingestion:

Do Not Induce Vomiting:
If swallowed, do not induce vomiting.
Rinse the mouth and drink plenty of water if the person is conscious.

Seek Medical Attention:
Seek immediate medical attention.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE), including gloves and safety goggles, to prevent skin and eye contact.

Ventilation:
Use in a well-ventilated area to minimize inhalation exposure.
Consider local exhaust ventilation if handling the substance in enclosed spaces.

Avoidance of Contact:
Avoid skin and eye contact.
Do not ingest the substance.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
In the event of a spill, contain and collect the material using appropriate absorbent materials.
Prevent the substance from entering waterways or sewer systems.
Follow established spill response procedures in accordance with local regulations.

Handling Precautions:
Avoid generating dust, aerosols, or mists.
Do not eat, drink, or smoke while handling the substance.
Implement good industrial hygiene practices in the workplace.

Static Electricity:
Take measures to prevent the buildup of static electricity.
Ground equipment and containers to dissipate static charges.

Compatibility:
Ensure compatibility with other substances and materials used in the workplace.
Avoid contact with incompatible materials.


Storage:

Storage Location:
Store N, N-dimethylurea in a cool, dry, and well-ventilated area.
Keep away from direct sunlight and heat sources.

Temperature:
Store at temperatures recommended by the manufacturer or within specified temperature ranges.
Avoid extreme temperature fluctuations.

Container Integrity:
Use containers made of materials compatible with N, N-dimethylurea.
Ensure containers are tightly sealed to prevent contamination and evaporation.

Separation from Incompatible Materials:
Store away from incompatible substances, such as strong acids, bases, and oxidizing agents.

Spill Containment:
Provide spill containment measures, such as secondary containment, to prevent environmental contamination.

Handling of Bulk Quantities:
For bulk quantities, use appropriate storage vessels and ensure compliance with local regulations.



SYNONYMS


1,3-Dimethylurea
Dimethylurea
N,N-Dimethylcarbamide
1,3-Dimethylcarbamide
Dimethylurea (1,3-DMU)
N,N-Dimethylurea
Dimethylurea (1,3)
NSC 21989
BRN 1209243
EINECS 209-819-0
AC1Q78GE
AI3-00957
1,3-Dimethylurea, Technical Grade
MFCD00008022
NSC21989
3-Dimethylurea
1,3-DIMETHYLUREA, 98%
N,N-Dimethyl Urea
1,3-DIMETHYLUREA, REAGENTPLUS, 99%
1,3-DIMETHYLUREA, 97%
N,N-dimethylcarbamide
1,3-Dimethylurea, 99%
N,N-DIMETHYLUREA, ANHYDROUS
1,3-Dimethylurea, purum, ≥99.0% (GC)
Dimethylurea (DMU)
1,3-Dimethylcarbamoylurea
Dimethylurea (3-DMU)
Carbamoyl-N,N-dimethylurea
3-Dimethylcarbamoylurea
Carbamide, N,N-dimethyl-
Dimethylcarbamoylurea
N,N-Dimethylurea
1,3-Bis(methylcarbamoyl)urea
1,3-Dimethylurea (DMU)
NSC 62944
Urea, 1,3-bis(methylcarbamoyl)-
N,3-Dimethylurea
1,3-Dimethylcarbamide
1,3-Dimethylcarbonylurea
N,3-Dimethylcarbamoylurea
1,3-Dimethylurea (DMU)
N,N-Dimethylcarbonylurea
N,N'-Dimethylurea
Dimethylcarbamoylcarbamide
3-Dimethylurea
1,3-Dimethylurea, anhydrous
Carbamide, 1,3-bis(methylcarbamoyl)-
1,3-Dimethylurea, BioReagent, for molecular biology
1,3-Dimethylurea, 99+%
Urea, 1,3-bis(methylcarbamoyl)-, hydrochloride
Dimethylcarbamoylurea
1,3-Dimethylcarbamoylurea
Carbamide, 1,3-dimethyl-
1,3-Dimethylcarbonylurea
Dimethylcarbamide
Carbamoyl-N,N-dimethyl urea
N,N-Dimethylcarbamoylurea
3-Dimethylcarbamide
1,3-Dimethylurea, anhydrous, 99%
1,3-Dimethylurea, for HPLC, 99%
1,3-Dimethylurea, certified reference material
1,3-Dimethylurea, solution 1.0 M in THF
1,3-Dimethylurea, solution 1.0 M in acetone
1,3-Dimethylurea, puriss. p.a., Reag. Ph. Eur.
N,N-Dimethylurea, anhydrous, 99%
N,N-Dimethylurea, analytical standard
Dimethylurea, 97%
1,3-Dimethylurea, PharmaGrade, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production
1,3-Dimethylurea, Vetec™ reagent grade, 98%
N,N-Dimethylurea, anhydrous, 98+%
1,3-Dimethylurea, pharmaceutical secondary standard; traceable to USP
N,N-Dimethylurea, BioUltra, ≥99.0% (T)
1,3-Dimethylurea, United States Pharmacopeia (USP) Reference Standard
N,N-Dimethylurea, purum, ≥98% (HPLC)
1,3-Dimethylurea, SAJ special grade, ≥97.0%
N,N DIMETHYLCYCLOHEXYLAMINE
n,n Dimethylcyclohexylamine IUPAC Name N,N-dimethylcyclohexanamine n,n Dimethylcyclohexylamine InChI 1S/C8H17N/c1-9(2)8-6-4-3-5-7-8/h8H,3-7H2,1-2H3 n,n Dimethylcyclohexylamine InChI Key SVYKKECYCPFKGB-UHFFFAOYSA-N n,n Dimethylcyclohexylamine Canonical SMILES CN(C)C1CCCCC1 n,n Dimethylcyclohexylamine Molecular Formula C8H17N n,n Dimethylcyclohexylamine CAS 98-94-2 n,n Dimethylcyclohexylamine Related CAS 2498-24-0 (hydrochloride) n,n Dimethylcyclohexylamine Deprecated CAS 130254-81-8, 75496-03-6 n,n Dimethylcyclohexylamine European Community (EC) Number 202-715-5 n,n Dimethylcyclohexylamine ICSC Number 1444 n,n Dimethylcyclohexylamine NSC Number 163904 n,n Dimethylcyclohexylamine RTECS Number GX1198000 n,n Dimethylcyclohexylamine UN Number 2264 n,n Dimethylcyclohexylamine UNII N1H19E7HTA n,n Dimethylcyclohexylamine DSSTox Substance ID DTXSID9026633 n,n Dimethylcyclohexylamine Physical Description Liquid n,n Dimethylcyclohexylamine Color/Form WATER-WHITE LIQ n,n Dimethylcyclohexylamine Boiling Point 323.6 °F at 760 mm Hg n,n Dimethylcyclohexylamine Melting Point -60 °C n,n Dimethylcyclohexylamine Flash Point 108 °F n,n Dimethylcyclohexylamine Solubility PARTLY SOL IN WATER; MISCIBLE WITH ALC, BENZENE, ACETONE n,n Dimethylcyclohexylamine Density 0.849 at 68 °F n,n Dimethylcyclohexylamine Vapor Density Relative vapor density (air = 1): 4.4 n,n Dimethylcyclohexylamine Vapor Pressure Vapor pressure, kPa at 25 °C: 0.4 n,n Dimethylcyclohexylamine LogP 2.01 n,n Dimethylcyclohexylamine Henrys Law Constant 2.35e-05 atm-m3/mole n,n Dimethylcyclohexylamine Autoignition Temperature 215 °C F n,n Dimethylcyclohexylamine Molecular Weight 127.23 g/mol n,n Dimethylcyclohexylamine XLogP3 1.9 n,n Dimethylcyclohexylamine Hydrogen Bond Donor Count 0 n,n Dimethylcyclohexylamine Hydrogen Bond Acceptor Count 1 n,n Dimethylcyclohexylamine Rotatable Bond Count 1 n,n Dimethylcyclohexylamine Exact Mass 127.1361 g/mol n,n Dimethylcyclohexylamine Monoisotopic Mass 127.1361 g/mol n,n Dimethylcyclohexylamine Topological Polar Surface Area 3.2 Ų n,n Dimethylcyclohexylamine Heavy Atom Count 9 n,n Dimethylcyclohexylamine Formal Charge 0 n,n Dimethylcyclohexylamine Complexity 72.6 n,n Dimethylcyclohexylamine Isotope Atom Count 0 n,n Dimethylcyclohexylamine Defined Atom Stereocenter Count 0 n,n Dimethylcyclohexylamine Undefined Atom Stereocenter Count 0 n,n Dimethylcyclohexylamine Defined Bond Stereocenter Count 0 n,n Dimethylcyclohexylamine Undefined Bond Stereocenter Count 0 n,n Dimethylcyclohexylamine Covalently-Bonded Unit Count 1 n,n Dimethylcyclohexylamine Compound Is Canonicalized Yes n,n Dimethylcyclohexylamine is a tertiary amine consisting of cyclohexane having a dimethylamino substituent.n,n Dimethylcyclohexylamine is a colorless liquid with a musky ammonia odor. Less dense than water.n,n Dimethylcyclohexylamine is a colorless liquid with a musky ammonia odor. Less dense than water.n,n Dimethylcyclohexylamine WAS BUBBLED WITH 0.2-0.3 L/MIN N CONTAINING 2020 PPM HYDROGEN SULFIDE FOR 15 MIN; THE HYDROGEN SULFIDE REMOVAL WAS 100%.n,n Dimethylcyclohexylamine CAN BE COLLECTED BY ASPIRATION THROUGH 0.01N HCL, EXTRACTED WITH CHCL3, AND DETERMINED BY COLORIMETRY USING A BLUE FILTER. THE METHOD WILL DETECT 0.5 MUG IN 3 ML 0.01N HCL.n,n Dimethylcyclohexylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.n,n Dimethylcyclohexylamine (DMEA), sometimes referred to as dimethylethylamine, is an organic compound with formula C4H11N. It is an industrial chemical that is mainly used in foundries as a catalyst for sand core production.Dimethylethylamine is a malodorous, volatile liquid at room temperature that is excreted at greater concentrations with larger dietary intake of trimethylamine.It has recently been identified as an agonist of human trace amine-associated receptor 5.n,n Dimethylcyclohexylamine is used in polyurethane plastics and textiles and as a chemical intermediate.n,n Dimethylcyclohexylamine is manufactured either by the reaction of methyl chloride or formaldehyde and hydrogen with cyclohexylamine (HSDB 1989).n,n Dimethylcyclohexylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.Industrial hygiene studies in polyurethane manufacturing plants have identified levels of 0.007-0.81 p.p.m. n,n Dimethylcyclohexylamine in air; however, these levels were not regarded as hazardous (Reisdorf and Haggerty 1982). There are no current exposure standards for n,n Dimethylcyclohexylamine and no documentation of human toxicological effects.n,n Dimethylcyclohexylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.n,n Dimethylcyclohexylamine catalyst is a strongly basic, clear, colorless-to-straw liquid tertiary amine. The material has a characteristic amine odor. n,n Dimethylcyclohexylamine catalyst will darken on standing, with no effect on reactivity. It is readily soluble in most polyols and organic solvents but is essentially insoluble in water. n,n Dimethylcyclohexylamine catalyst is recommended for evaluation in a broad range of rigid foams. A major application is insulation foams, including spray, slabstock, board laminate and refrigeration formulations. n,n Dimethylcyclohexylamine catalyst is also used in rigid foam furniture frame and decorative parts manufacturing. It can be used alone without any tin catalyst, or used together with other JD catalysts depending on process and specific requirements.Binary mixtures of water and organic solvents are described as the aqueous solutions of organic solvents, which are usually spatially heterogeneous on the scale of a few molecular sizes but homogeneous on longer length scales, that is, microheterogeneity. For the water–organic solvent binary mixtures with microheterogeneity, most organic solvents are miscible with water at any ratio. Interestingly, some slightly water-miscible organic solvents can also be used to prepare binary mixtures with microheterogeneity. In this study, n,n Dimethylcyclohexylamine (DMCHA) was used to prepare binary mixtures with microheterogeneity and CO2 switchability. With the help of conductivity, Fourier–transform infrared spectroscopy, ultraviolet–visible spectroscopy, and dynamic light scattering measurements, we found that water molecules are hydrogen-bonded together to form clusters over the water content range of 9 to 27 wt %, exhibiting microheterogeneity in the binary mixture. The size of the water clusters increases slightly with increasing water content. What is more, the n,n Dimethylcyclohexylamine–water mixtures can be reversibly split into two phases by alternate bubbling of CO2 and N2, exhibiting excellent CO2 switchability. The binary mixtures can be used as reaction media for the synthesis of CaCO3 nanoparticles. Binary mixtures with microheterogeneity can also be formed under high salinity or high temperature conditions or be prepared using other slightly water-miscible organic solvents, opening up more interesting possibilities for binary mixtures with microheterogeneity.UV–vis absorption spectra of methylene blue and Nile red; dynamic IFT of n,n Dimethylcyclohexylamine–water at 17 °C; maximum XW value for binary mixtures of water and alcohols with different carbon numbers; maximum XW value for n,n Dimethylcyclohexylamine–water mixtures at different temperatures; phase behavior of the n,n Dimethylcyclohexylamine–water mixture with XW of 60 wt %; phase behavior of the n,n Dimethylcyclohexylamine–water mixture with XW of 20 wt %; species distribution of n,n Dimethylcyclohexylamine; size distribution of water clusters in the original n,n Dimethylcyclohexylamine–water mixture and in the mixture treated with CO2/N2; and illustration of recovering and recycling n,n Dimethylcyclohexylamine in the preparation process of CaCO3 nanoparticles.Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable containers as far as possible. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: Fully encapsulating, vapor-protective clothing should be worn for spills and leaks with no fire. ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors. Absorb with earth, sand or other non-combustible material and transfer to containers (except for Hydrazine). Use clean, non-sparking tools to collect absorbed material. LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces.No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.The substance is corrosive to the skin, eyes and respiratory tract. Corrosive on ingestion. Inhalation may cause lung oedema. The effects may be delayed. Medical observation is indicated.Wear self-contained breathing apparatus, rubber boots, heavy rubber gloves. If entering spill area, wear self-contained breathing apparatus and full protective clothing, including boots.CORROSIVE/ Fire or Explosion: Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.FLAMMABLE LIQUIDS - CORROSIVE/ Health: May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.CALL Emergency Response Telephone Number on Shipping Paper first. If Shipping Paper not available or no answer, refer to appropriate telephone number listed on the inside back cover. As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. Ventilate closed spaces before entering.Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible.Binary mixtures of water and organic solvents are described as the aqueous solutions of organic solvents, which are usually spatially heterogeneous on the scale of a few molecular sizes but homogeneous on longer length scales, that is, microheterogeneity. For the water–organic solvent binary mixtures with microheterogeneity, most organic solvents are miscible with water at any ratio. Interestingly, some slightly water-miscible organic solvents can also be used to prepare binary mixtures with microheterogeneity. In this study, N,N-dimethylcyclohexylamine (DMCHA) was used to prepare binary mixtures with microheterogeneity and CO2 switchability. With the help of conductivity, Fourier–transform infrared spectroscopy, ultraviolet–visible spectroscopy, and dynamic light scattering measurements, we found that water molecules are hydrogen-bonded together to form clusters over the water content range of 9 to 27 wt %, exhibiting microheterogeneity in the binary mixture. The size of the water clusters increases slightly with increasing water content. What is more, the DMCHA–water mixtures can be reversibly split into two phases by alternate bubbling of CO2 and N2, exhibiting excellent CO2 switchability. The binary mixtures can be used as reaction media for the synthesis of CaCO3 nanoparticles. Binary mixtures with microheterogeneity can also be formed under high salinity or high temperature conditions or be prepared using other slightly water-miscible organic solvents, opening up more interesting possibilities for binary mixtures with microheterogeneity.JD DMCHA catalyst is a strongly basic, clear, colorless-to-straw liquid tertiary amine. The material has a characteristic amine odor. JD DMCHA catalyst will darken on standing, with no effect on reactivity. It is readily soluble in most polyols and organic solvents but is essentially insoluble in water.JD DMCHA catalyst is recommended for evaluation in a broad range of rigid foams. A major application is insulation foams, including spray, slabstock, board laminate and refrigeration formulations. JD DMCHA catalyst is also used in rigid foam furniture frame and decorative parts manufacturing. It can be used alone without any tin catalyst, or used together with other JD catalysts depending on process and specific requirements.A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause pulmonary edema; Can be absorbed through skin; [ICSC] Irritating or corrosive to animal skin; Irritating to rabbit eyes; Not sensitizing to guinea pig skin using skin painting test; [IUCLID] Causes muscle contraction or spasticity in lethal-dose studies of mice (inhalation and oral routes); [RTECS] Causes burns; Toxic if inhaled; [Alfa Aesar MSDS]For switchable hydrophilicity solvent (SHS) systems (N,N-Dimethylcyclohexylamine (DMCA), water, and carbon dioxide): the density, viscosity, refractive index and conductivity at (283.15–308.15) K and 0.1 Mpa, were measured. The apparent molar volumes were determined as a function of composition at each temperature from experimental data. Based on Masson’s equation limiting apparent molar volumes and Masson’s coefficient SV describing the character of interactions were calculated. The relative viscosity values were adjusted to obtain the viscosity B coefficients and dB/dT values. It has been observed that there exist strong solute-solvent and solute-solute interactions in these systems, and DMCAH-bicarbonate salt acts as structure-maker in aqueous solvent.Oil recovery was improved using the tertiary amine, N,N-dimethylcyclohexylamine (DMCHA), a powerful and promissory switchable solvent, in simulated conditions similar to the Colombian crude oil reserves. Firstly, the Colombian crude oil (CCO) and the soil were characterized completely. Afterwards, an aged crude-rock system was obtained to use DMCHA that gave an oil crude extraction of 80% in our preliminary studies. Thus, a sand-pack column (soil-kaolin, 95 : 5) frame saturated with CCO was used to simulate the conditions, in which DMCHA could recover the oil. After the secondary recovery process, 15.4–33.8% of original oil in place (OOIP) is obtained. Following the injection of DMCHA, the recovery yield rose to 87–97% of OOIP. Finally, 54–60% of DMCHA was recovered and reinjected without affecting its potential in the simulated conditions.Due to the reduction of combustible fossil stockpiles, alternative energy solutions are emerging each day; however, crude oil still represents the most used energy source. In 2017, oil demand grew on average by 1.8%, or 1.7 million barrels per day (bpd), becoming the third consecutive year where crude oil demand grew above the 10 year average of 1.2%. Meanwhile, it is projected that 26% of the energy will be derived from petroleum until 2040. Therefore, petroleum extraction is a practice that is increasing as well as its different processing stages. When a reservoir is found, after the drilling process, production stage begins and primary recovery starts when crude oil rises to the surface naturally due to current reservoir pressure. As reservoir pressure drops, secondary recovery is required by injection of external fluids that normally could be present in the reservoir, such as water and/or gas, mainly to boost the pressure to displace the remaining oil. When no more crude oil is produced in secondary recovery, injection of special fluids such as chemicals and miscible gases and/or the injection of thermal energy are necessary, and this process is called tertiary recovery .By the time the reservoir pressure is depleted, only a 5–15% of original oil in place (OOIP) is recovered; therefore, several strategies have been implemented to access the remaining reserves of approximately 80%. This allows economic equilibrium between investment and commercialization. Therefore, in the secondary phase around 20–30% of oil in place (OIP) is recovered. This artificial drive may look attractive economically, but microscopic capillary forces and sweep efficiency are the main drawbacks of this method. In order to increase sweep efficiency, polymer fluids are used, and surfactant fluids are used to reduce capillary forces. Using these two methods, recovery factor (RF) increases up to 40% of OIP. From these first reports, several polymers and surfactants, including several structural moieties to get higher RF values, have been designed for EOR (enhanced oil recovery).Despite polymers, alkali, surfactants, or a mixture, SP and ASP methods are currently used; other proposals have been recently evaluated to increase RF. Therefore, dispersion of nanoparticles, ionic liquids, biosurfactants, microorganisms, and deep eutectic solvents, among other alternatives, has been used to increase production in this industry. Due to the technical and environmental drawbacks of these methods, there is constant interest to have new alternatives to increase the RF. One strategy includes the usage of amines because of its capacity to act as interfacial tension reducer agents (ITRA). Thus, these kinds of molecules could be used as precursor for in situ surfactant formation and then to act as ITRA.On the other hand, oil-solid separation is a process well known from domestic cleaning to petroleum extraction; therefore, the usage of common solvents like toluene, naphtha, and xylenes, among others, promotes high efficiency in solvent extraction and oil recovery. Nevertheless, these common solvents are normally too volatile and highly toxic; then, Jessop and coworkers proposed a special amine, N,N-dimethylcyclohexylamine (DMCHA), as a powerful solvent to extract crude from Canadian oil sands as unconventional ores. Although the capacity of amines to extract crude from porous rock has been proved, new amines have been synthesised to be employed like a solvent in oil-solid ore separation; however, DMCHA resulted to be more effective in the extraction process (68%) than synthetic amine (63%). In addition, due to its switchable polarity, recyclability of DMCHA opens the window towards the synthesis of new kinds of surfactants with tertiary amine moieties. Therefore, the possibility to recover the chemicals after the injection process without changes of crude oil properties and water quality is really attractive.Colombia is the third largest oil producer in South America (EIA), and the technology of enhanced oil recovery (tertiary recovery) is just in the developing stage. This is illustrated by the fact that only 23 of 280 fields were found in natural depletion. Recovery methods such as water alternated gas (WAG) have been applied, and RF estimated until 2010 was between 0.1 and 65% depending on the injection method. Therefore, we wanted to expose the potential of amines like DMCHA for extraction and recovery of the Colombian crude oil.The light crude oil sample comes from a Colombian oil reservoir. The characterization of the oil sample is shown in Table 1. Synthetic brine was prepared to 1.5% wt. of NaCl. Carbon dioxide was acquired with 99% purity from a local company. Carbonated water was prepared by bubbling CO2 via a gas dispersion tube into deionized water at atmospheric pressure. N,N-Dimethylcyclohexylamine (DMCHA) was used as Merck reagent degree with 99% purity. The sand used in the sand-pack column was collected from a natural soil.Sand was washed according to the modified Mattigod protocol . Briefly, the sand sample was milled and sieved through an 80/100 mesh sieve. Then, the resulting mineral was washed with deionized water, mixing 67 g of mineral by 1 L of water. This mixture was dispersed using magnetic stirring for 45 min. The pH of this dispersed mixture was adjusted to 9.5 with a NaOH solution 0.1 M. After 15 min of stirring, the dispersed mixture was centrifuged at 3000 rpm for 15 min. The mixture was resuspended in water, and the pH was adjusted to 3 using HCl 0.1 N. Then, the mixture was centrifuged again and washed until pH = 5.5. Mineral was dried and preserved under N2 atmosphere and characterized by SEM-EDS and XRD.XRD mineral characterization was performed in a Bruker powder diffractometer D8 model with Da Vinci geometry in the range of 3.5° to 70° (2θ). The sample was milled, homogenized, and brought to a particle size less than 38 µm. The qualitative analysis of the crystalline phases in the sample was made by comparing the observed profile with the diffraction profiles reported in the database of the ICDD (International Center for Diffraction Data).SEM and EDS were performed with a Tescan model MIRA 3 FEG-SEM and A65cSED, respectively. The samples had to be coated with gold before analysis. SEM images were obtained between 26x to 1000x (scale from 2 mm to 50 microns) up to an electron acceleration voltage of up to 10 kV and an intensive beam of 3.Sand-pack column was created using tubes and caps of PVC material, with Hastelloy fittings. Measures of the sand pack were defined according to protocols established in the literature. Within the tube, a mixture of washed sand (95%) and kaolin (5%) was slowly added and gently compacted in the column looking for a sufficiently tight porous medium with low permeability (Figure 2(a)). After packing the sand tightly, a top sieve and cap were fixed. The caps on both ends of the column were provided with holes for insertion of inlet and outlet tubes. Valves and two manometers were placed, one at the entrance of the tube and one to the outlet of the tube (Figure 2).As the tertiary amine showed a good efficacy to remove crude oil, it was used to demonstrate its potential in the oil-rock separation, reducing interaction between rock and crude oil in a dynamic test. After brine injection, an average PV of 84 mL was measured. Then, 3 PV of amine was injected in three different runs for the EOR simulation process, using the designed sand-pack system (Table 3).Pereira et al. performed the same simulations with similar dimensions of the sand pack and obtained a PV between 90 and 94 mL. This value is close to our PV value, 79–90 mL, where a more diluted brine of 1500 ppm was used instead of 20000 ppm used in the study by Pereira et al. The PV should be higher as lower concentration brine was used. Kaolin was added to reduce the sand-pack porosity and thus to have a less PV values. In the same way, another report showed that for this sand-pack column design, PV was around 90 mL. Therefore, it can be inferred that water saturation was performed under controlled conditions, and the results obtained are comparable with those in the literature.Waterflooding process is the most common protocol in secondary oil recovery technologies, and low water salinity flooding can yield better results than seawater injection. However, for brine injection, several parameters, such as rock composition, reservoir temperature, and crude oil properties, among others, have to be known and controlled. Due to the known physicochemical composition of Colombian produced water (TDS values), a brine concentration value of 1500 ppm of NaCl was selected. In the secondary recovery process, Sorw between 6.5 and 15.3 mL from the OOIP was achieved, obtaining between 15.5 and 33.8% of crude oil. Oil recovery rates after waterflooding can differ and could be associated with several factors. These include crude oil temperature, brine concentration, and mineral parameters. All these parameters were controlled for all runs. If column is not filled with the crude or the mineral packaging is not well done, preferential roads can be formed in the sand pack, and nonviscous liquid like water will not contact with the crude and will not be able to move it. As crude oil saturation was the same in all three entries, it was considered low sweep efficiency as hypothesis for entries 1 and 3 results because of heterogeneity of our mineral.In regard to the tertiary recovery using DMCHA, it was observed that the injection process generated an increase in the system’s pressure, reaching 60 psi in the inlet during injection. It could be due to crude oil viscosity and hydrophilic-lipophilic interaction. Effluent (mixture crude oil-DMCHA) was collected and was of lower viscosity compared with original crude oil. The interaction between amine and the crude oil results appears to be favourable, where amine acts like an efficient solvent for washing our impregnated crude oil mineral. After effluents were collected, they (amine-crude) were bubbled with CO2 looking for crude oil separation from the nitrogen compound. This process generates an emulsion, but after a few minutes, it disappeared, and recovery crude oil was calculated as % AmOR (amine oil recovery) for the 3 entries with higher values up to 87%.Oil-solid separation with switchable solvents can occur through dissolution or via interfacial tension (IFT) reduction, reducing the capillary number. In this last case, amine is used as carbonated salt in water solution. In this study, DMCHA was used as a solvent, not as a amine-water mixture, and the IFT was not taken into account. However, it has been demonstrated that amines such as triethyl amine (Et3N) can be mixed with water until 11% wt., reducing the IFT between water and crude oil from 33.7 m·Nm−1 to 13.2 m·Nm−1, demonstrating potential dual activity as solvent and as surfactant.The oil recovery factor depends on several conditions, and crude oil has been obtained between 5 and 80% of yield with an estimated average value of 37%. In this preliminary research, in the usage of tertiary amines as switchable solvent (DMCHA) for tertiary recovery simulation on Colombian crude oil, amine allowed to us to obtain an average crude oil extraction of 87%.The crude oil was left to room temperature, and the effect of this parameter on amine behaviour was not evaluated as the same as thermal stability related to the field’s temperature at Colombia. As the crude oil was obtained from the Llanos basin in Colombia, where field temperatures are lower than 80°C (maximum temperature registered for a Colombian field) and the boiling point of DMCHA has been determined (162°C), thermal stability should not be a drawback. However more studies of heavy crude oil cEOR at different temperatures are being investigated.Regarding the extracted petroleum physical properties, they were slightly affected after the injection process (Table 1).To understand the interaction between mineral, crude oil, and DMCHA, the PZC of the model rock was used (Figure 1). Therefore, PZC was observed, pH = 7, meaning that the crude oil will not be strongly adsorbed on mineral surface; further interaction of amine-rock will also not be favourable. At the same time, when amine was injected, pH increased and PZC was negative, favouring rejection of electron rich region in crude oil molecules and mineral. On the other hand, amine and crude oil will interact favourably.At the end of the flooding process, crude oil was analysed by NMR to identify any modification of the crude oil composition or chemical changes in crude oil molecules. In addition, a test was carried out to determine if amine could remain in the final effluent after CO2 bubbling. For this experiment, a methodology proposed by Molina and coworkers was applied, considering different kinds of protons that were related to the original crude oil and each effluent after the recovery process . n,n Dimethylcyclohexylamine has been used: • as switchable hydrophilicity solvent (SHS) for the extraction of lipids from freeze-dried samples of Botryococcus braunii microalgae for biofuel production • as catalyst in three-component organocatalyzed Strecker reaction on water.
N,N-4-TRIMETHYLANILINE
N,N,4-trimethylaniline is a chemical compound with the molecular formula C9H13N.
N,N-4-trimethylaniline is an aromatic amine, specifically a derivative of aniline where three methyl groups (-CH3) are substituted onto the nitrogen atom of the amine group.
N,N-4-trimethylaniline is a N-methyl-N-alkylaniline.

CAS Number: 99-97-8
Molecular Formula: C9H13N
Molecular Weight: 135.21
EINECS Number: 202-805-4

N,N-Dimethyl-p-toluidine, 99-97-8, N,N,4-TRIMETHYLANILINE, Dimethyl-p-toluidine, Benzenamine, N,N,4-trimethyl-, Dimethyl-4-toluidine, N,N-Dimethyl-4-methylaniline, N,N,4-Trimethylbenzenamine, p-Methyl-N,N-dimethylaniline, p-(Dimethylamino)toluene, N,N-Dimethyl-p-tolylamine, 4-Dimethylaminotoluene, N,N-Dimethyl-para-toluidine, p-Toluidine, N,N-dimethyl-, NSC 1785, p,N,N-Trimethylaniline, Dimetil-p-toluidina, N,N-Dimethyl-4-toluidine, 1-(Dimethylamino)-4-methylbenzene, 4,N,N-Trimethylaniline, S8XC5939VU, DTXSID0021832, NSC-1785, NL 65-100, DTXCID401832, p-N,N-Trimethylaniline, CAS-99-97-8, Dimetil-p-toluidina [Italian], CCRIS 1001, EINECS 202-805-4, UNII-S8XC5939VU, Benzeneamine,N,N,4-trimethyl-, dimethyltolylamine, HSDB 8202, MFCD00008316, N,4-Trimethylaniline, dimethyl-(p-tolyl)-amine, EC 202-805-4, Benzenamine,N,4-trimethyl-, SCHEMBL28378, MLS001050174, 4-dimethylamino-1-methylbenzene, 4,N,N-Trimethylaniline, 99%, CHEMBL1462714, DIMETHYLTOLYLAMINE [INCI], N,N-Dimethyl-p-methylphenylamine, NSC1785, Tox21_201370, Tox21_300062, AC-368, AKOS015915159, N,N-DIMETHYL-P-TOLUIDINE [IARC], NCGC00091397-01, NCGC00091397-02, NCGC00091397-03, NCGC00254201-01, NCGC00258922-01, SMR001216586, D0807, FT-0629511, FT-0636092, FT-0656134, NS00002247, E75885, EN300-7266829, 4,N,N-Trimethylaniline, purum, >=98.0% (GC), Q2051705, W-100002, Z1002998236, N,N-DIBENZYL-1,4,10,13-TETRAOXA-7,16-DIAZACYCLOOCTADECANE.

N,N-4-trimethylaniline is reaction with vinyl ether catalyzed by CuCl2 has been reported to afford tetrahydroquinolines.
N,N-4-trimethylaniline is radical cation undergoes reaction with the anthracene radical anion and generation of electrogenerated chemiluminescence (ECL) has been observed.

N,N-4-trimethylaniline is a versatile organic compound extensively utilized in scientific research.
N,N-4-trimethylaniline is applications span across the synthesis of numerous compounds, including,agrochemicals, pesticides, amino acids, peptides, and nucleotides.
N,N-4-trimethylaniline finds utility in the creation of polymers, dyes, and catalysts.

As a colorless, crystalline solid, N,N-4-trimethylaniline easily dissolves in most organic solvents. As a nucleophilic reagent capable of reacting with both electrophiles like carbonyl compounds and halides, as well as nucleophiles such as amines and alcohols.
With N,N-4-trimethylaniline is wide range of applications, N,N-Dimethyl-p-toluidine serves as a crucial reagent for the synthesis of various compounds in laboratory settings.

N,N-4-trimethylaniline is a tertiary amine that can undergo iron-catalyzed oxidative C-C coupling with phenylacetylene and benzamide in the presence of tert-butylperoxide to form N,4-dimethyl-N-(3-phenylprop-2-ynyl)benzenamine and N-((methyl(p-tolyl)amino)methyl)benzamide, respectively.
N,N-4-trimethylaniline is an organic compound with formula (CH3)3C6H2NH2.
N,N-4-trimethylaniline is an aromatic amine that is of commercial interest as a precursor to dyes.

N,N-4-trimethylaniline is prepared by selective nitration of mesitylene, avoiding oxidation of the methyl groups, followed by reduction of the resulting nitro group to the aniline.
N,N-4-trimethylaniline is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.
N,N-4-trimethylaniline is presented to the CSWG for review because it is a highproduction-volume chemical that has the potential for widespread human exposure from its use in
dental materials and bone cements.

N,N-4-trimethylaniline is used in the following products: pH regulators and water treatment products, adhesives and sealants, leather treatment products and laboratory chemicals.
N,N-4-trimethylaniline is used in the following areas: health services and scientific research and development. N,N-dimethyl-para-toluidine is used for the manufacture of: textile, leather or fur.
Other release to the environment of N,N-4-trimethylaniline is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

N,N-4-trimethylaniline is used in the following products: adhesives and sealants.
Release to the environment of N,N-4-trimethylaniline can occur from industrial use: formulation of mixtures.
N,N-4-trimethylaniline is used in the following products: adhesives and sealants, textile treatment products and dyes, pH regulators and water treatment products and laboratory chemicals.

N,N-4-trimethylaniline has an industrial use resulting in manufacture of another substance (use of intermediates).
N,N-4-trimethylaniline is the accelerator in the redox initiator-accelerator system used commercially to cure methyl methacrylate monomers.
Polymerization is rarely complete; N,N-4-trimethylaniline retained in bone cements and dental materials is sufficient to cause exposure to surgical staff, dental prosthetic device manufacturers, and denture wearers, among others.

N,N-4-trimethylaniline is thought to be the causative agent in “burning mouth” observed in denture wearers and it may be responsible for aseptic loosening of hip replacements
N,N-4-trimethylaniline is used in the following areas: formulation of mixtures and/or re-packaging, health services and scientific research and development.
N,N-4-trimethylaniline is used for the manufacture of: chemicals

N,N-4-trimethylaniline is a building block to a variety of bulky ligands.
Condensation with glyoxal gives the 1,2-diimine ligands.
An example is glyoxal-bis(mesitylimine), a yellow solid that is synthesized by condensation of 2,4,6-trimethylaniline and glyoxal.

The diimine is a useful precursor to popular NHC ligands including IMes.
N,N-4-trimethylaniline, as found in 2nd generation Grubbs' catalyst, are also prepared from this compound.
The metabolism of orally administered N,N-4-trimethylaniline in male F344 rats was investigated.

The rat urinary metabolite profile was determined by analytical reverse-phase high performance liquid chromatography (HPLC).
Four radiolabeled peaks were observed, isolated, and purified by solid-phase extraction (SPE) and preparative HPLC methods.
The 4 peaks were identified as p-(Nacetylhydroxyamino)hippuric acid (M1), N,N-dimethyl-para-toluidine N-oxide (M2), N-methyl-p-toluidine (M3), and parent N,Ndimethyl-para-toluidine.

Metabolites M1 and M2 were identified by spectrometric and spectroscopic methods, including mass fragmentation pattern identification from both liquid chromatography/mass spectrometry and gas chromatography/mass spectrometry, and from chemical analysis of nuclear magnetic resonance spectra.
Structural confirmation of metabolite M2 was accomplished by comparison with a synthetic standard.
Peaks M3 and the peak suspected to be N,N-4-trimethylaniline were identified by comparison of their HPLC retention times and mass fragmentation patterns with authentic standards of N-methyl-ptoluidine and N,N-dimethyl-para-toluidine, respectively.

N,N-4-trimethylaniline metabolism is similar to that reported for N,Ndimethylaniline.
N,N-4-trimethylaniline has a triarylamine structure with one 2,4,6-methylated phenyl and two 4-brominated phenyl rings.
The two bromo functional groups at the end of each benzene rings enable it to extend its conjugation via Suzuki, Yamamoto or Stille coupling reactions.

N,N-4-trimethylaniline is a convenient intermediate for the synthesis of polytriarylamines (PTAAs) via Yamamoto polycondensation.
PTAAs are electron rich thus commonly used as electron transport layer for perovskite solar cells and OLED devices.
PTAAs can normally be deposited by solution processing at lower temperature, significantly reducing possible thermal damage to the active layer.

N,N-4-trimethylaniline is prepared from the reaction of 2,4,6-trimethylaniline with 1-bromo-4-iodobenzene (Buchwald-Hartwig amination) in the presence of 1,1′-ferrocenediyl-bis(diphenylphosphine) (dppf) and sodium tert-butoxide in toluene.
N,N-4-trimethylaniline is a clear to yellow liquid with an aromatic odor; insoluble in water.
N,N-4-trimethylaniline is an accelerator in the redox initiator-accelerator system used commercially to cure methyl methacrylate monomers.

N,N-4-trimethylaniline is a high-production volume chemical with potential for widespread human exposure through its use in dental materials and bone cements.
N,N-4-trimethylaniline has been used in the preparation of acrylic denture materials for the past 50 years.
N,N-4-trimethylaniline is used as the accelerator for the cement in most of the hip and bone replacements to activate the polymerization reaction.

N,N-4-trimethylaniline is found in industrial glues and artificial fingernail preparations and is used as an intermediate in dye and pesticide synthesis.
N,N-4-trimethylaniline is a fine chemical that belongs to the family of aminomethyl compounds.
N,N-4-trimethylaniline is a versatile building block that can be used in the synthesis of complex compounds and as a reagent or speciality chemical in research.

N,N-4-trimethylaniline is also a useful intermediate for reactions and scaffolds in organic syntheses.
N,N-4-trimethylaniline can be used as an alternative to the more commonly used 4-aminophenol.
This compound has been observed to have high purity and quality with no detectable impurities.

N,N-4-trimethylaniline is used as a polymerization accelerator in the manufacture of bone cements and dental materials, in industrial glues, and as an intermediate in dye and pesticide synthesis.
Thus, there is potential for human exposure to N,N-4-trimethylaniline, an aromatic amine with a structural alert for potential DNA reactivity.
The National Toxicology Program (NTP) is evaluating the toxicity and carcinogenicity of
N,N-4-trimethylaniline in male and female Fischer 344 rats and B6C3F1 mice.

To aid in the design and interpretation of those studies, investigated the excretion and tissue distribution of oral and intravenous (IV) doses of radiolabeled N,N-4-trimethylaniline in these strains of rodents.
A single low (2.5 mg/kg), mid (25 mg/kg) or high (250 mg/kg) dose of carbon-14 labeled N,N-4-trimethylaniline was administered.
Excreta collected for up to 72 hr after dosing and tissues collected at sacrifice were analyzed for total radioactivity.

N,N-4-trimethylaniline belongs to the class of substituted anilines, which are organic compounds containing an amino group attached to a benzene ring.
The presence of the three methyl groups makes N,N-4-trimethylaniline a tertiary amine.
N,N-4-trimethylaniline, is the ingredient that induces the reaction giving rise to free radicals capable of initiating polymerization of the acrylic monomers. Polymerization is rarely complete.

Five commercially available bone cements were analysed by high-performance liquid chromatography for detecting the residual content of an accelerator, the amine N,N-4-trimethylaniline, after curing.
It was found that the concentration of N,N-4-trimethylaniline in aqueous extracts decreases with time, being almost absent 7 days after curing.
Differences were noticed among the cements; residual N,N-4-trimethylaniline is higher in cements prepared with higher content of the amine.

N,N-4-trimethylaniline is verified that N,N-dimethyl-para-toluidine's toxic effect on cell cultures is dose-related; a delay in the cell replication cycle is induced in vitro.
Damage is reversible, thus justifying the low bone cement toxicity that is clinically ascertained.
The use of solid phase extraction (SPE) and high performance liquid chromatography (HPLC) for the analysis of toxic components eluted from methyl-methacrylate polymer (pMMA) dental materials was described.

Two pMMA composite resins, Yunifast and Acron, were analyzed.
Yunifast was polymerized at room temperature, and Acron at 100 degrees-C. Each sample was then placed in equine serum at room temperature, and serum was replaced daily.
The serum extract was subjected to SPE and HPLC, for methylmethacrylate, N,N-dimethyl-p-toluidine (N,N-dimethyl-para-toluidine), and benzoylperoxide (BPO) (initiator and stimulator for the polymerization) analysis.

Results showed that the MMA and N,N-4-trimethylaniline eluted was in the order of 10 to 100 parts per million.
Almost negligible amounts of BPO and benzoic-acid were also eluted.
A greater amount of these compounds was eluted from Yunifast, a more pliant material.

N,N-4-trimethylaniline showed greater elution than MMA.
The hydrophilic portion of Yunifast was more cytotoxic than the hydrophobic portion, and contained BA and p-toluidine as major and minor components.
The /study/ conclude that the rigidity of the material is critical to the extractable quantity, and recommend that both Yunifast and Acron be immersed in hot water before use in order to remove hydrophilic toxic compounds from these pMMA dental materials.

The National Occupational Exposure Survey, which was conducted by the National Institute for Occupational Safety and Health (NIOSH) between 1981 and 1983, estimated that 62,720 workers were potentially exposed to N,N-4-trimethylaniline in the workplace (NIOSH, 1990).
There is potential for widespread human exposure to N,N-dimethyl-para-toluidine in occupational settings where bone cements, dental prostheses, industrial glues, and artificial fingernails are manufactured or used.
Exposure to N,N-4-trimethylaniline may be a concern because of the possible release of unreacted chemicals from polymeric composites.

The rate constant for the vapor-phase reaction of N,N-4-trimethylaniline with photochemically-produced hydroxyl radicals has been estimated as 2.0X10-10 cu cm/molecule-sec at 25 °C using a structure estimation method.
This corresponds to an atmospheric half-life of about 2 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm.
N,N-4-trimethylaniline is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions.

N,N-4-trimethylaniline does not contain chromophores that absorb at wavelengths >290 nm and, therefore, is not expected to be susceptible to direct photolysis by sunlight.
Being a tertiary amine, N,N-4-trimethylaniline is less basic than primary or secondary amines.
However, N,N-4-trimethylaniline can still act as a weak base in chemical reactions.

N,N-4-trimethylaniline can be synthesized through various methods, including the alkylation of aniline using methylating agents.
The specific synthetic route may depend on the intended application.
N,N-4-trimethylaniline and related aromatic amines can find applications in various industrial processes.
They may be used in the synthesis of dyes, pigments, pharmaceuticals, and other specialty chemicals.
Aromatic amines, including N,N-4-trimethylaniline, are important intermediates in the synthesis of azo dyes.
Azo dyes are a significant class of synthetic dyes widely used in the textile and other industries.

N,N-4-trimethylaniline can serve as a chemical intermediate in the synthesis of various compounds.
N,N-4-trimethylaniline is reactivity allows for the creation of diverse chemical structures.
Like many aromatic amines, N,N-4-trimethylaniline may pose health and safety risks, and precautions should be taken when handling this compound.

Exposure to aromatic amines is typically minimized in industrial settings through engineering controls and personal protective equipment.
Due to the potential health hazards associated with certain aromatic amines, including their potential carcinogenicity, regulatory agencies may impose restrictions on their use and require compliance with safety and environmental regulations.
Aromatic amines, including derivatives like N,N-4-trimethylaniline, are often studied in the field of organic chemistry for their reactivity and potential applications in the synthesis of new compounds.

The Koc of N,N-4-trimethylaniline is estimated as 260, using a log Kow of 2.81 and a regression-derived equation.
According to a classification scheme, this estimated Koc value suggests that N,N-4-trimethylaniline is expected to have moderate mobility in soil.
The pKa of N,N-4-trimethylaniline is 5.63, indicating that this compound will exist partially in the cation form and cations generally adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts. A Kd value of 380 for sorption to monmorillonite has been reported.

The Henry's Law constant for N,N-4-trimethylaniline is estimated as 7.0X10-5 atm-cu m/mole derived from its vapor pressure, 0.178 mm Hg, and water solubility, 455 mg/L.
This Henry's Law constant indicates that N,N-4-trimethylaniline is expected to volatilize from water surfaces.
Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec) is estimated as 1 day.

The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec) is estimated as 10 days.
N,N-4-trimethylaniline's estimated Henry's Law constant indicates that volatilization from moist soil surfaces may occur.
N,N-4-trimethylaniline is not expected to volatilize from dry soil surfaces based upon its vapor pressure.

Melting point: -25°C
Boiling point: 211 °C(lit.)
Density: 0.937 g/mL at 25 °C(lit.)
vapor density: >1 (vs air)
vapor pressure: 0.1 hPa (20 °C)
refractive index: n20/D 1.546(lit.)
Flash point: 182 °F
storage temp.: Store below +30°C.
solubility: 0.65g/l
form: Liquid
pka: pK1:7.24(+1) (25°C)
color: Clear yellow
explosive limit 7%
Water Solubility: Miscible with alcohol, ether and chloroform. Immiscible with water.
BRN: 774409
Dielectric constant: 3.3(20℃)
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey: GYVGXEWAOAAJEU-UHFFFAOYSA-N
LogP: 1.729-2.81 at 35℃

N,N-4-trimethylaniline neutralizes acids in exothermic reactions to form salts plus water.
May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.

N,N-4-trimethylaniline is an accelerator in the redox initiator-accelerator system used commercially to cure methyl methacrylate monomers.
Polymerization is rarely complete.
N,N-4-trimethylaniline is a high-production volume chemical with potential for widespread human exposure through its use in dental materials and bone cements.

N,N-4-trimethylaniline has been used in the preparation of acrylic denture materials for the past 50 years.
N,N-4-trimethylaniline is used as the accelerator for the cement in most of the hip and bone replacements to activate the polymerization reaction at concentrations ranging from 0.7% to 2.6%.
N,N-4-trimethylaniline is found in industrial glues and artificial fingernail preparations and is used as an intermediate in dye and pesticide synthesis.

N,N-4-trimethylaniline has a shorter setting time (11.5 minutes) than some alternative accelerators.
As an aromatic amine, N,N-4-trimethylaniline exhibits reactivity typical of such compounds.
N,N-4-trimethylaniline can undergo reactions like aromatic substitution, where the hydrogen atoms on the aromatic ring can be replaced by other functional groups.

Some aromatic amines, depending on their structures, have been studied for their potential impact on biological systems and the environment.
These compounds may be subject to regulations to minimize their release and exposure.
N,N-4-trimethylaniline, like other aromatic amines, can be utilized in organic synthesis for the preparation of various organic compounds.

N,N-4-trimethylaniline is reactivity allows it to participate in a variety of chemical reactions.
Some aromatic amines, including certain derivatives, are known to exhibit catalytic activity in specific reactions.
Researchers may explore their catalytic potential in various transformations.

The use of the term N,N-4-trimethylaniline suggests the presence of three methyl groups on the nitrogen atom.
The specific isomerism, stereochemistry, and substitution pattern on the aromatic ring can affect the compound's properties.
Aromatic amines, including N,N-4-trimethylaniline, can be analyzed using various analytical techniques, such as chromatography and spectroscopy.

These methods are employed for identification and quantification in research and industrial settings.
Like many chemical compounds, N,N-4-trimethylaniline requires careful handling due to potential health hazards.
This includes the use of appropriate personal protective equipment, adherence to safety protocols, and awareness of its potential toxicity.

Aromatic amines are commonly employed in research laboratories for their versatility in organic synthesis.
Researchers may study their properties and reactivity to develop new methodologies or create novel compounds.
Some aromatic amines serve as building blocks in the synthesis of pharmaceuticals and bioactive compounds.

Researchers may explore their potential pharmacological activities.
The study of structure-activity relationships involves understanding how the chemical structure of a compound influences its biological or chemical activity.
Aromatic amines, including N,N-4-trimethylaniline, can be studied in this context.

Aromatic amines may find applications in biocatalysis and enzymatic reactions, where certain enzymes can catalyze specific transformations involving these compounds.
Acryl resins used in dental practice are blends of poly(methyl methacrylated) particles and methyl methacrylate monomer, or copolymers of methyl methacrylate with styrene or other acrylic monomers.
This blend is a slurry of high viscosity that is hardened by the free radical polymerization of the monomeric components.

N,N-4-trimethylaniline's production and use as a polymerization accelerator in the manufacture of bone cements and dental materials, in industrial glues, and as an intermediate in dye and pesticide synthesis may result in its release to the environment through various waste streams.
If released to air, a vapor pressure of 0.178 mm Hg at 25 °C indicates N,N-4-trimethylaniline will exist solely as a vapor in the atmosphere.
Vapor-phase N,N-dimethyl-para-toluidine will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 2 hrs.

N,N-4-trimethylaniline does not contains chromophores that absorb at wavelengths >290 nm and, therefore, is not expected to be susceptible to direct photolysis by sunlight.
If released to soil, N,N-4-trimethylaniline is expected to have moderate mobility based upon an estimated Koc of 260.
The pKa of N,N-4-trimethylaniline is 5.63, indicating that this compound will exist partially in the cation form in the environment and cations generally adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts.

Volatilization of the neutral species from moist soil surfaces is expected to be an important fate process based upon an estimated Henry's Law constant of 7.0X10-5 atm-cu m/mole.
N,N-4-trimethylaniline is not expected to volatilize from dry soil surfaces based upon its vapor pressure.
Biodegradation data in soil or water were not available.

If released into water, N,N-4-trimethylaniline is not expected to adsorb to suspended solids and sediment based upon the estimated Koc.
Volatilization from water surfaces is expected to be an important fate process based upon this compound's estimated Henry's Law constant.
Estimated volatilization halflives for a model river and model lake are 1 and 10 days, respectively.

An estimated BCF of 33 suggests the potential for bioconcentration in aquatic organisms is moderate.
Hydrolysis is not expected to be an important environmental fate process since this compound lacks functional groups that hydrolyze under environmental conditions (pH 5 to 9).
Occupational exposure to N,N-4-trimethylaniline may occur through inhalation and dermal contact with this compound at workplaces where N,N-dimethyl-para-toluidine is produced or used.

Uses:
N,N-4-trimethylaniline is an amine accelerator for the polymerization of e.g. dental methacrylic restorative materials.
N,N-4-trimethylaniline is used as a polymerization catalyst for polyesters, acrylate and epoxy resins.
N,N-4-trimethylaniline is also used as a hardener for dental cements and in adhesives.

N,N-4-trimethylaniline serves as an intermediate for photographic chemicals, in industrial glues, in artificial fingernail preparations, colorants, pharmaceuticals.
N,N-4-trimethylaniline reacts with vinyl ether in the presence of copper(II) chloride gives tetrahydroquinolines.
Further, N,N-4-trimethylaniline is used to accelerate polymerization of ethyl methacrylate.

Aromatic amines, including N,N-4-trimethylaniline, are important intermediates in the synthesis of azo dyes.
These dyes are widely used in the textile industry for coloring fabrics.
Aromatic amines can be used as intermediates in the synthesis of pharmaceutical compounds.

They may play a role in the creation of specific drug molecules or building blocks.
N,N-4-trimethylaniline, like other aromatic amines, can participate in various chemical reactions, making it valuable in the synthesis of diverse organic compounds.
Some aromatic amines exhibit catalytic properties and may be employed in catalytic processes.

Catalysis is a key area where certain organic compounds play a crucial role in promoting chemical reactions.
N,N-4-trimethylaniline is likely used in research laboratories for organic synthesis and chemical studies.
N,N-4-trimethylaniline is reactivity and properties may be explored in the development of new methodologies or understanding structure-activity relationships.

In research and educational settings, N,N-4-trimethylaniline may be used as a reagent in various laboratory experiments and demonstrations.
Aromatic amines, including N,N,4-trimethylaniline, may find applications in the polymer industry.
They can be used as monomers or additives in the synthesis of certain polymers.

Some aromatic amines are utilized in the formulation of adhesives, where they can contribute to the chemical and physical properties of the adhesive.
Certain aromatic amines may have antioxidant properties.
While the specific antioxidant properties of N,N,4-trimethylaniline need to be assessed, some aromatic amines are known for their ability to inhibit oxidation.

Aromatic amines have historical applications in the field of photography.
They were used in the formulation of certain photographic chemicals and processes.
Some aromatic amines are investigated for their potential use as corrosion inhibitors.

They may be employed to protect metals from corrosion in certain industrial applications.
Aromatic amines, including certain derivatives, have been used as color developers in the photographic industry, contributing to the formation of color images.
Aromatic amines may be used as auxiliaries in the textile industry for processes such as dyeing and finishing.

In biological and biochemical research, certain aromatic amines are used as probes or indicators in experimental studies.
Some aromatic amines are explored as potential additives in fuels to improve combustion efficiency and reduce emissions.
Aromatic amines can be used in the electroplating industry as additives in plating baths to enhance the quality of plated coatings.

Aromatic amines may be used in laboratories for corrosion testing and evaluation of materials.
Aromatic amines are sometimes used in the rubber industry, where they can function as accelerators or activators in the vulcanization process, contributing to the formation of strong and durable rubber products.
Some aromatic amines may serve as additives in fuels and lubricants to enhance performance, improve stability, and reduce wear and friction in engines.

Certain aromatic amines are employed in the electronics industry and plastics manufacturing as components in the synthesis of polymers and as stabilizers to prevent degradation.
Aromatic amines can be used as analytical reagents in laboratories for the detection and quantification of specific compounds.
Their reactivity with certain substances makes them useful in various analytical methods.

Aromatic amines, due to their chemical properties, may be involved in certain wastewater treatment processes for the removal of pollutants and contaminants.
In the plastics and textile industries, certain aromatic amines are utilized as antistatic agents to reduce static electricity buildup.
Aromatic amines, particularly those with specific electronic properties, are investigated for their potential use in gas sensing devices for the detection of gases and vapors.

Some aromatic amines play a role in the development of materials used in photovoltaic devices and solar cells.
Aromatic amines may be included in formulations for surface coatings to enhance adhesion, flexibility, and resistance to environmental factors.
In the field of agrochemicals, certain aromatic amines may be components of formulations for pesticides or plant growth regulators.

Aromatic amines are subjects of study in material science, where their properties and reactivity are explored for the design and development of new materials with specific functionalities.
Aromatic amines can be involved as catalysts in certain hydrogenation reactions, facilitating the addition of hydrogen to unsaturated compounds.
In certain metal extraction processes, aromatic amines may be used as extractants for the separation of metals from ores or solutions.

Certain aromatic amines have been historically used in the field of color photography, contributing to the development of color images in photographic processes.
Some aromatic amines may be used as components in flame retardants, which are substances added to materials to reduce their flammability.
Aromatic amines, including certain derivatives, may act as catalysts in organic synthesis reactions, facilitating the transformation of reactants into desired products.

Aromatic amines may be explored for their potential role as soil amendments in agriculture, influencing soil properties and nutrient availability.
Certain aromatic amines can be involved in the preservation and conservation of art and cultural heritage objects, particularly in the treatment of certain materials.
Aromatic amines may be utilized in chemical analysis techniques for the detection of specific compounds or as indicators in various analytical methods.

Some aromatic amines may have the ability to form complexes with metal ions, which can have applications in areas such as metal extraction and separation.
In metal surface treatment processes, aromatic amines might be employed as additives or components in formulations to enhance surface properties.
Certain aromatic amines are investigated for their electrochemical properties, making them potential candidates for use in batteries, sensors, or other electrochemical devices.

Some aromatic amines have been studied in the context of cancer research due to their potential mutagenic and carcinogenic properties.
Understanding their effects can contribute to cancer prevention strategies.
Aromatic amines may be involved in supramolecular chemistry studies, exploring the assembly of molecules into larger, organized structures through non-covalent interactions.

In the field of tissue engineering, certain aromatic amines may be explored for their potential role in the development of biomaterials and scaffolds.
Some aromatic amines with specific optical properties are investigated for their potential use in photothermal therapy, a medical treatment that utilizes light-absorbing substances to generate heat and selectively destroy targeted cells.
Certain aromatic amines are studied for their potential as hydrogen storage materials in the context of alternative energy research.

Safety Profile:
Aromatic amines can be toxic, and exposure to them may cause adverse health effects.
The specific toxicity can vary among different aromatic amines and depends on factors such as chemical structure, concentration, and duration of exposure.
Some aromatic amines are known or suspected carcinogens, meaning they have the potential to cause cancer.

Prolonged or repeated exposure to these compounds may increase the risk of developing cancer.
Certain aromatic amines are mutagenic, meaning they have the potential to cause genetic mutations.
Mutations can lead to various health issues, including cancer.

Aromatic amines may cause irritation to the skin and eyes upon contact.
Skin exposure can lead to dermatitis, and eye exposure may result in irritation or damage.
Inhalation of vapors or dust containing aromatic amines may irritate the respiratory system, leading to symptoms such as coughing, difficulty breathing, or irritation of the nose and throat.

Health Hazard:
Inhalation, ingestion or skin contact with material may cause severe injury or death.
Contact with molten N,N-4-trimethylaniline may cause severe burns to skin and eyes.
Avoid any skin contact.

Effects of contact or inhalation may be delayed.
Fire may produce irritating, corrosive and/or toxic gases.
Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard:
Combustible material: may burn but does not ignite readily.
When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards.
Contact with metals may evolve flammable hydrogen gas.

Containers may explode when heated.
Runoff may pollute waterways.
N,N-4-trimethylaniline may be transported in a molten form.

N,N-AMINOETHYLETHANOOL AMINE (AEEA)
N,N'-BIS(2-HYDROXYETHYL)-2-NITRO-P-PHENYLENEDIAMINE N° CAS : 84041-77-0 Nom INCI : N,N'-BIS(2-HYDROXYETHYL)-2-NITRO-P-PHENYLENEDIAMINE Nom chimique : 2,2'-[(2-Nitro-1,4-phenylene)diimino]bisethanol N° EINECS/ELINCS : 281-856-4, Agent colorant pour cheveux : Colore les cheveux
N,N-BIS-STEARYL-ETHYLENEDIAMINE
N,N-bis-stearyl-ethylenediamine is an amide wax.
N,N-bis-stearyl-ethylenediamine is the abbreviation of Ethylene Bis Stearamide, which is a synthetic wax with high melting point.
N,N-bis-stearyl-ethylenediamine is derived from stearic acid and ethylenediamine.


CAS Number: 110-30-5
EC Number: 203-755-6
MDL number: MFCD00059224
Molecular Formula: C38H76N2O2 / [CH3(CH2)16CONHCH2-]2


N,N-bis-stearyl-ethylenediamine is an ethylenebisstearamide, specifically developed to afford low, consistent viscosities and superior cost performance in paper pulp defoamer applications.
N,N-bis-stearyl-ethylenediamine is an organic compound with the formula (CH2NHC(O)C17H35)2.


N,N-bis-stearyl-ethylenediamine is a synthetic wax that has fatty amide groups that can interact with the surface of a variety of nanoparticles.
N,N-bis-stearyl-ethylenediamine disperses evenly through the polymer in the melt phase, and migrates to the surface where it forms a thin lubricating layer that reduces coefficient of friction between surfaces and reduces unwanted adhesion.


N,N-bis-stearyl-ethylenediamine is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.
N,N-bis-stearyl-ethylenediamine is useful as defoamer for paper making and textile processing .
N,N-bis-stearyl-ethylenediamine is also available in bead form.


N,N-bis-stearyl-ethylenediamine is ethylene-bis-stearamide of non-vegetable origin.
N,N-bis-stearyl-ethylenediamine is derived from stearic acid and ethylenediamine.
N,N-bis-stearyl-ethylenediamine is white or slight yellow powder or granule.


N,N-bis-stearyl-ethylenediamine is white spherical particle, non-toxic and no side effect on humans.
N,N-bis-stearyl-ethylenediamine is insoluble in most organic solvents at room temperature.
N,N-bis-stearyl-ethylenediamine is an amide wax of type N,N-bis-stearyl-ethylenediamine.


N,N-bis-stearyl-ethylenediamine is compatible with styrene & styrenic copolymer, PVC, PO and PS.
N,N-bis-stearyl-ethylenediamine is derived from the reaction of ethylenediamine and stearic acid.
N,N-bis-stearyl-ethylenediamine is a white solid that provides a slippery coating for a variety of applications.


N,N-bis-stearyl-ethylenediamine has no influence on the transparency of the Polymers.
The recommended dosage levels are 500-2000 ppm in films and 0.2-1.0% in molding applications.
N,N-bis-stearyl-ethylenediamine is a hard and brittle white high melting point wax.


N,N-bis-stearyl-ethylenediamine is a secondary bis-amide additive.
N,N-bis-stearyl-ethylenediamine has good anti-blocking properties in polyolefins.
N,N-bis-stearyl-ethylenediamine is stable to acid, alkali and water medium.


N,N-bis-stearyl-ethylenediamine is soluble in hot chlorinated hydrocarbons and aromatic hydrocarbon solvents.
N,N-bis-stearyl-ethylenediamine is an amide wax.
N,N-bis-stearyl-ethylenediamine has low acid value ( free fatty acid ), high melting point, and excellent white colour, and high purity.


N,N-bis-stearyl-ethylenediamine acts as a slip and anti-block additive.
N,N-bis-stearyl-ethylenediamine is based on a non-vegetable origin, secondary bis-amide.
N,N-bis-stearyl-ethylenediamine is an organic compound with the formula (CH2NHC(O)C17H35)2.


N,N-bis-stearyl-ethylenediamine is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.
N,N-bis-stearyl-ethylenediamine is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.
N,N-bis-stearyl-ethylenediamine's industrial products are slightly yellow particles or white powder, non-toxic, and have no side effects on the human body.


N,N-bis-stearyl-ethylenediamine has no influence on the transparency of the Polymers.
Synthhetic wax having high melting point, N,N-bis-stearyl-ethylenediamine has some functions as internal and external lubricant, releasing and dispersion agent of pigment for the most thermosetting and thermoplastic resins.


N,N-bis-stearyl-ethylenediamine exhibits good thermostability and excellent slip properties.
N,N-bis-stearyl-ethylenediamine is an organic, synthetic wax.
N,N-bis-stearyl-ethylenediamine has a shelf life of 365 days.


N,N-bis-stearyl-ethylenediamine is a secondary bis amide effective as an anti-block agent and process aid for polyolefins.
N,N-bis-stearyl-ethylenediamine is derived from the reaction of ethylenediamine and stearic acid.
N,N-bis-stearyl-ethylenediamine offers mold release benefits in polyamides (nylon).


N,N-bis-stearyl-ethylenediamine also functions as an external lubricant for PVC and a process aid for polyolefins.
N,N-bis-stearyl-ethylenediamine is suitable for composites, styrenics and rubber.
N,N-bis-stearyl-ethylenediamine is an amide wax of type N,N-bis-stearyl ethylenediamine with particularly good thermostability.


N,N-bis-stearyl-ethylenediamine is manufactured by stearic acid and ethylenediamine.
N,N-bis-stearyl-ethylenediamine is derived from the reaction of ethylenediamine and stearic acid.
N,N-bis-stearyl-ethylenediamine is a white solid of low toxicity that provides a slippery coating for a variety of applications.


N,N-bis-stearyl-ethylenediamine is a hard and brittle white high melting point wax.
N,N-bis-stearyl-ethylenediamine's industrial products are slightly yellow particles or white powder, non-toxic, and have no side effects on the human body.
N,N-bis-stearyl-ethylenediamine can be prepared by carrying out the reaction between stearic acid and ethylenediamine.


N,N-bis-stearyl-ethylenediamine is a hard and brittle white high melting point wax, it's industrial products are slightly yellow fine particles, insoluble in most solvents at room temperature, stable to acids and bases, and aqueous media, soluble in hot chlorinated hydrocarbons and aromatic hydrocarbons solvents, it’s powder slippery feeling strong, above 80 ℃ to water with wettability of the compound.


N,N-bis-stearyl-ethylenediamine is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits.
N,N-bis-stearyl-ethylenediamine is derived from the reaction of ethylenediamine and stearic acid.
N,N-bis-stearyl-ethylenediamine is a white solid of low toxicity that provides a slippery coating for a variety of applications.


N,N-bis-stearyl-ethylenediamine is a synthetic wax produced by the reaction of ethylenediamine and stearic acid.
N,N-bis-stearyl-ethylenediamine is a white, odorless, and tasteless solid, with a melting point ranging from 139°C to 142°C.
N,N-bis-stearyl-ethylenediamine is a synthetic wax with high melting point.


N,N-bis-stearyl-ethylenediamine is an organic compound with the formula (CH2NHC(O)C17H35)2.
N,N-bis-stearyl-ethylenediamine is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.
N,N-bis-stearyl-ethylenediamine is known for its excellent properties, such as high melting point, low toxicity, and good thermal stability.



USES and APPLICATIONS of N,N-BIS-STEARYL-ETHYLENEDIAMINE:
N,N-bis-stearyl-ethylenediamine is used as lubricant with good inner or outer lubricant action and has good coordination when used together with other lubricants as high grade alcohols, aliphatic acid esters, calcium stearate and paraffin.
Application of N,N-bis-stearyl-ethylenediamine: Water treatment


In the processing of ABS, AS, hard PVC, polyformaldehyde, polycarbonate, polyurethane and phenolformaldehyde resins, N,N-bis-stearyl-ethylenediamine is used as lubricant demoulding agent with a quantity of 0.5~1.5 %.
N,N-bis-stearyl-ethylenediamine can also be used as a process aid, for example to improve dispersion of fillers.


N,N-bis-stearyl-ethylenediamine is used as an additive for hot melt adhesives.
N,N-bis-stearyl-ethylenediamine is used as an internal and external slip agent in many thermoplastic and thermosetting plastics, the most representative ones are ABS, PS, ABS, PVC, also used in PE, PP, PVAC, cellulose, Accurate, Nylon, phenolic-Resin, amino plastics.


N,N-bis-stearyl-ethylenediaminehas a good finish and good film release.
As a lubricant of polyformaldehyde, the addition amount is 0.5%, which improves the melt flow rate and the film release, and the whiteness, thermal stability and physical index of polyformaldehyde all reach the superior index.


Chemical fiber: N,N-bis-stearyl-ethylenediamine can improve the heat and weather resistance, fluidity of polyester, polyamide fiber, and give a certain anti-static effect.
As a lubricant of polyformaldehyde, the addition amount is 0.5%, which improves the melt flow rate and the film release, and the whiteness, thermal stability and physical index of polyformaldehyde all reach the superior index.


Chemical fiber: N,N-bis-stearyl-ethylenediamine can improve the heat and weather resistance, fluidity of polyester, polyamide fiber, and give a certain anti-static effect.
Release agent: Phenolic resin for sand casting with N,N-bis-stearyl-ethylenediamine can be used as a release agent.


N,N-bis-stearyl-ethylenediamine improves flow and has no influence on transparency of polymers.
N,N-bis-stearyl-ethylenediamine acts as a lubricant, release & antiblocking agent for all engineering resins and dispersing agent for masterbatch applications.


N,N-bis-stearyl-ethylenediamine is used as anti-adhesive agent for various polymer film or sheets.
An addition of 0.5-1 % of N,N-bis-stearyl-ethylenediamine can not only prevent the occurrence of air bubbles but also make the plastic bags be slippery so as to be opened easily.


N,N-bis-stearyl-ethylenediamine can remarkably enhance the heat-resistant and weather-resistant properties while coordinating with chief stabilizer in formulation of inorganic filler for PVC and polyolefin.
As N,N-bis-stearyl-ethylenediamine has strong cohesions with pigment or other filler, it can improve the dispersion and coupling property of fillers in the polymers to enhance the commercial value of the products.


N,N-bis-stearyl-ethylenediamine powder does not affect the transparency of polymers and acts as lubricant in a wide variety of polymers like PVC, PO, PS and engineering plastics.
N,N-bis-stearyl-ethylenediamine is used as nucleation transparency agent to reduce the nucleating time in compounds such as polyolefins, polyformaldehyde and polyamide, promote the structure of resin to become fine, thus improve the mechanical property and transparency of the products.


In synthetic fiber industry, N,N-bis-stearyl-ethylenediamine can improve the heat-resistant, weather-resistant property of polyester and polyamide and bring about certain antistatic effects.
N,N-bis-stearyl-ethylenediamine is used in the spinning of antistatic nylon fiber as additive and also is able to reduce the breaking of yarn.


N,N-bis-stearyl-ethylenediamine is used as processing auxiliary of rubber.
Besides the lubricant demoulding property and modifying performance of filler surface, N,N-bis-stearyl-ethylenediamine can raise the surface fineness of rubber pipes and rubber plates to act as rubber surface polishing agent.


N,N-bis-stearyl-ethylenediamine is used added in the coating production to increase the uniform dispersion of pigment and filler, improve the surface leveling property of baking paint, prevent the stripping off of paint film and improve water-proof and acid-resistant and alkali-resistant property.
In nitrocellulose lacquers, N,N-bis-stearyl-ethylenediamine can bring about the flatting action.


N,N-bis-stearyl-ethylenediamine is used as additive EBS can be incorporated directly into polymers to prevent any unwanted adhesion.
N,N-bis-stearyl-ethylenediamine is used as lubricant in powder metallurgy (PM) steels to reduce the inter-particle and die-wall friction during pressing and hence improve powder compressibility and ejection of the component from the compaction tool.


N,N-bis-stearyl-ethylenediamine is used as defoamer/ anti-foaming agent and coating component of paper for paper-making industry.
N,N-bis-stearyl-ethylenediamine is used added in the manufacturing process of dope and oil paint to enhance salt mist and dampproof effect and to improve performance of paint remover.


As N,N-bis-stearyl-ethylenediamine has good wearable performance and smoothing performance, fits for improving polishing performance of lacquer, air release of surface with holes, it is also well used as dulling agent for polishing furniture and printing ink.
N,N-bis-stearyl-ethylenediamine improves the kneading, processing and vulcanization performance of rubber grains in the processing of rubber.


N,N-bis-stearyl-ethylenediamine is used in the following products: polymers, lubricants and greases, metal working fluids, pharmaceuticals and cosmetics and personal care products.
N,N-bis-stearyl-ethylenediamine is used for the manufacture of: rubber products, textile, leather or fur, machinery and vehicles and chemicals.


Cosmetic Uses of N,N-bis-stearyl-ethylenediamine: viscosity controlling agents
N,N-bis-stearyl-ethylenediamine is used in the following areas: formulation of mixtures and/or re-packaging.
N,N-bis-stearyl-ethylenediamine is used for the manufacture of: rubber products and plastic products.


N,N-bis-stearyl-ethylenediamine is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.
Because of its excellent lubricating properties, N,N-bis-stearyl-ethylenediamine is widely used internally and/or externally in most plastics such as ABS, PS, PP, etc.


N,N-bis-stearyl-ethylenediamine can also be a binder in the precise engineering metal part.
Due to its good dispersing ability and surface migration N,N-bis-stearyl-ethylenediamine can be used in printing inks.
Another field of application is the bitumen industry: When used in asphalt binder for road making (asphalt modifiers), N,N-bis-stearyl-ethylenediamine increases its softening point and enhances its visco-elasticity.


N,N-bis-stearyl-ethylenediamine is not only has good external lubrication effect, but also has good internal lubrication effect, which improves the fluidity and demoulding property of melted plastic in plastic molding process, thus improving the yield of plastic processing, reducing energy consumption, and making the product obtain high surface smoothness and smoothness.


N,N-bis-stearyl-ethylenediamine, a new plastic lubricant developed in recent years, is widely used in the molding and processing of PVC products, ABS, high impact polystyrene, polyolefin, rubber and plastic products.
N,N-bis-stearyl-ethylenediamine is a bis-amide polymer additive that lowers the temperature at which the asphalt softens.


N,N-bis-stearyl-ethylenediamine is non-toxic and can be dispersed evenly through the polymer in the melt phase.
N,N-bis-stearyl-ethylenediamine is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


N,N-bis-stearyl-ethylenediamine is used in the following products: adhesives and sealants, lubricants and greases, coating products, polishes and waxes and washing & cleaning products.
N,N-bis-stearyl-ethylenediamine can be found in products with material based on: rubber (e.g. tyres, shoes, toys) and fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys).


N,N-bis-stearyl-ethylenediamine is used as processing aid for resins and polymers and as defoaming agent.
N,N-bis-stearyl-ethylenediamine is traditionally used as lubricant and binder for cold compaction of powdered metal parts.
N,N-bis-stearyl-ethylenediamine is used as processing aid for resins and polymers and as defoaming agent.


N,N-bis-stearyl-ethylenediamine has proven mould release action in polyamides, and is a lubricant for PVC.
N,N-bis-stearyl-ethylenediamine is a bis-amide anti-blocking additive used to prevent blocking and as anti-tack of adhesives.
N,N-bis-stearyl-ethylenediamine atomized is traditionally used as lubricant and binder for cold compaction of powdered metal parts.


N,N-bis-stearyl-ethylenediamine is used as a processing aid for resins and polymers and as a defoaming agent.
N,N-bis-stearyl-ethylenediamine, a new plastic lubricant developed in recent years, is widely used in the molding and processing of PVC products, ABS, high impact polystyrene, polyolefin, rubber and plastic products.


N,N-bis-stearyl-ethylenediamine is compared with traditional lubricants such as paraffin wax, polyethylene wax, stearate, etc.
N,N-bis-stearyl-ethylenediamine is used in powder metallurgy.
N,N-bis-stearyl-ethylenediamine can also be used as a process aid, for example to improve dispersion of fillers.


N,N-bis-stearyl-ethylenediamine can also be a binder in the precise engineering metal part.
N,N-bis-stearyl-ethylenediamine is used Dispersing agent for masterbatch applications, preferably for engineering resins and PVC, and Modifier in textile auxiliaries


N,N-bis-stearyl-ethylenediamine is used as anti-adhesive agent for various polymer film or sheets.
An addition of 0.5-1 % of N,N-bis-stearyl-ethylenediamine can not only prevent the occurrence of air bubbles but also make the plastic bags be slippery so as to be opened easily.


N,N-bis-stearyl-ethylenediamine beaded is an effective lubricant, processing aid, slip additive and pigment dispersant aid for most polymers.
N,N-bis-stearyl-ethylenediamine is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.


Because of it's excellent lubricating properties, N,N-bis-stearyl-ethylenediamine is widely used internally and/or externally in most plastics such as ABS, PS, PP, etc.
N,N-bis-stearyl-ethylenediamine is traditionally used as lubricant and binder for cold compaction of powdered metal parts.


N,N-bis-stearyl-ethylenediamine not only has good external lubrication effect, but also has good internal lubrication effect, which improves the fluidity and demoulding property of melted plastic in plastic molding process, thus improving the yield of plastic processing, reducing energy consumption, and making the product obtain high surface smoothness and smoothness.


N,N-bis-stearyl-ethylenediamine is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.
N,N-bis-stearyl-ethylenediamine is used as a processing aid for resins and polymers and as a defoaming agent.
Cosmetic Uses of N,N-bis-stearyl-ethylenediamine: viscosity controlling agents


N,N-bis-stearyl-ethylenediamine is used as Release agent and flow promoter for all engineering resins, Styrenics and their copolymers
N,N-bis-stearyl-ethylenediamine is used Lubricant in powder metal molding, rubber, adhesives, coatings, wire drawing, wood plastic composite, Defoamer in paper, Lubricant for Polyacetals, Water repellent for paper, Intermediate for defoamers, and Delustering agent for furniture finishes and printing inks.


N,N-bis-stearyl-ethylenediamine is used as nucleation transparency agent to reduce the nucleating time in compounds such as polyolefins, polyformaldehyde and polyamide, promote the structure of resin to become fine, thus improve the mechanical property and transparency of the products.
N,N-bis-stearyl-ethylenediamine is used in the spinning of antistatic nylon fiber as additive and also is able to reduce the breaking of yarn.


In nitrocellulose lacquers, N,N-bis-stearyl-ethylenediamine can bring about the flatting action.
N,N-bis-stearyl-ethylenediamine derived from stearic acid with ethylene diamine is a synthetic was used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability.


N,N-bis-stearyl-ethylenediamine is used for lubricant of plastic and metal molding, adhesion preventives, viscosity modifier, anti-corrosion of wax, water resistance of coating and spray paint.
N,N-bis-stearyl-ethylenediamine is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.


Because of its excellent lubricating properties N,N-bis-stearyl-ethylenediamine is widely used internally and/or externally in most plastics such as ABS, PS, PP etc.
N,N-bis-stearyl-ethylenediamine can be found in: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.


N,N-bis-stearyl-ethylenediamine is a synthetic wax that has fatty amide groups that can interact with the surface of a variety of nanoparticles.
N,N-bis-stearyl-ethylenediamine can be used for a wide range of applications such as lubricants, activators and dispersing agents that reduce the friction in the system and increase the rate of processing.


N,N-bis-stearyl-ethylenediamine is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.


N,N-bis-stearyl-ethylenediamine is used as additive Ethylenebisstearamide can be incorporated directly into polymers to prevent any unwanted adhesion.
N,N-bis-stearyl-ethylenediamine is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.


N,N-bis-stearyl-ethylenediamine has proven mold release benefits in nylon and is a lubricant for PVC.
N,N-bis-stearyl-ethylenediamine can be found in: outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).


N,N-bis-stearyl-ethylenediamine can remarkably enhance the heat-resistant and weather-resistant properties while coordinating with chief stabilizer in formulation of inorganic filler for PVC and polyolefin.
N,N-bis-stearyl-ethylenediamine is an internal additive and can be incorporated into resin as supplied or via masterbatch / pre-blend.


Due to it's good dispersing ability and surface migration N,N-bis-stearyl-ethylenediamine can be used in printing inks.
A field of application is the bitumen industry: When used in asphalt binder for road making (asphalt modifiers), N,N-bis-stearyl-ethylenediamine increases its softening point and enhances its visco-elasticity.


N,N-bis-stearyl-ethylenediamine is used as processing aid for resins and polymers and as defoaming agent.
N,N-bis-stearyl-ethylenediamine is used as lubricant with good inner or outer lubricant action and has good coordination when used together with other lubricants as high grade alcohols, aliphatic acid esters, calcium stearate and paraffin.


N,N-bis-stearyl-ethylenediamine is traditionally used as lubricant and binder for cold compaction of powdered metal parts.
In the processing of ABS, AS, hard PVC, polyformaldehyde, polycarbonate, polyurethane and phenolformaldehyde resins, N,N-bis-stearyl-ethylenediamine is used as lubricant demoulding agent with a quantity of 0.5~1.5 %.


As N,N-bis-stearyl-ethylenediamine has strong cohesions with pigment or other filler, N,N-bis-stearyl-ethylenediamine can improve the dispersion and coupling property of fillers in the polymers to enhance the commercial value of the products.
N,N-bis-stearyl-ethylenediamine is used in the following areas: formulation of mixtures and/or re-packaging.


N,N-bis-stearyl-ethylenediamine is used for the manufacture of: rubber products and plastic products.
N,N-bis-stearyl-ethylenediamine is used in the following products: polymers, lubricants and greases, metal working fluids, pharmaceuticals and cosmetics and personal care products.


N,N-bis-stearyl-ethylenediamine is used as additive N,N-bis-stearyl-ethylenediamine can be incorporated directly into polymers to prevent any unwanted adhesion.
Adhesive pellets or film often develop adhesion between the polymer pellets or layers when exposed to elevated temperatures and pressures.


N,N-bis-stearyl-ethylenediamine is used in the following products: lubricants and greases, polymers, washing & cleaning products, inks and toners, metal working fluids, textile treatment products and dyes and coating products.
N,N-bis-stearyl-ethylenediamine is used release agent and flow promoter for all engineering resins, Styrenics and their copolymers.


N,N-bis-stearyl-ethylenediamine is used slip- and anti-blocking agent for polyolefins and PVC, especially for film applications and also lubricant for wood plastic composites and plastics.
N,N-bis-stearyl-ethylenediamine can also be used as a process aid, for example to improve dispersion of fillers.


N,N-bis-stearyl-ethylenediamine can be found in industrial use: formulation of mixtures, formulation in materials, as processing aid, manufacturing of the substance and in processing aids at industrial sites.
N,N-bis-stearyl-ethylenediamine is a bis-amide polymer additive that lowers the temperature at which the asphalt softens.


N,N-bis-stearyl-ethylenediamine is used in the following areas: formulation of mixtures and/or re-packaging and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
N,N-bis-stearyl-ethylenediamine can be found in: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).


N,N-bis-stearyl-ethylenediamine is a bis-amide polymer additive that lowers the temperature at which the asphalt softens.
N,N-bis-stearyl-ethylenediamine is used as processing aid for resins and polymers and as defoaming agent.
N,N-bis-stearyl-ethylenediamine is an effective lubricant, processing aid, slip additive and pigment dispersant aid for most polymers.


N,N-bis-stearyl-ethylenediamine can also be used as a process aid, for example to improve dispersion of fillers.
N,N-bis-stearyl-ethylenediamine is used to prevent the adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.


N,N-bis-stearyl-ethylenediamine migrates to the surface of the polymer where it forms a thin lubricating layer.
N,N-bis-stearyl-ethylenediamine can be used for a wide range of applications such as lubricants, activators and dispersing agents that reduce the friction in the system and increase the rate of processing.


N,N-bis-stearyl-ethylenediamine acts as a dispersing agent or internal/external lubricant in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.


N,N-bis-stearyl-ethylenediamine also finds use in adhesives and powder metallurgy.
N,N-bis-stearyl-ethylenediamine is an ethylenebisstearamide, specifically developed to afford low, consistent viscosities and superior cost performance in paper pulp defoamer applications.


Useful as defoamer for paper making and textile processing .
N,N-bis-stearyl-ethylenediamine is used for the manufacture of: rubber products, textile, leather or fur, machinery and vehicles and chemicals.
N,N-bis-stearyl-ethylenediamine is used dispersing agent for masterbatch applications, preferably for engineering resins and PVC.


N,N-bis-stearyl-ethylenediamine is synthetic wax that is widely used as a release agent, antistatic agent, and antifoaming agent.
N,N-bis-stearyl-ethylenediamine is used as processing auxiliary of rubber. Besides the lubricant demoulding property and modifying performance of filler surface, N,N-bis-stearyl-ethylenediamine can raise the surface fineness of rubber pipes and rubber plates to act as rubber surface polishing agent.


N,N-bis-stearyl-ethylenediamine improves the kneading, processing and vulcanization performance of rubber grains in the processing of rubber.
N,N-bis-stearyl-ethylenediamine is added in the coating production to increase the uniform dispersion of pigment and filler, improve the surface leveling property of baking paint, prevent the stripping off of paint film and improve water-proof and acid-resistant and alkali-resistant property.


Experience has shown that simple manual mixing prior to processing will normally give an acceptable dispersion though, mechanical means are preferred.
Typical addition levels vary depending on polymer and lubrication required.
N,N-bis-stearyl-ethylenediamine acts as a slip and anti-block agent, mold release agent and lubricant for PVC.


N,N-bis-stearyl-ethylenediamine is used in powder metallurgy.
Lubrication performance is excellent, anti-calcium salt ability is strong, drag reduction effect is good, used for drilling in saturated brine to reduce power consumption.


N,N-bis-stearyl-ethylenediamine can be found in industrial use: in processing aids at industrial sites, as processing aid, in the production of articles, formulation in materials, formulation of mixtures and of substances in closed systems with minimal release.
N,N-bis-stearyl-ethylenediamine is widely used as a lubricant and processing aid in various industries, including plastics, coatings, and rubber.


N,N-bis-stearyl-ethylenediamine is also used as release agents, antistatic agents, and antifoaming agents.
In synthetic fiber industry, N,N-bis-stearyl-ethylenediamine can improve the heat-resistant, weather-resistant property of polyester and polyamide and bring about certain antistatic effects.


N,N-bis-stearyl-ethylenediamine is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.


N,N-bis-stearyl-ethylenediamine provides typical slip and anti blocking characteristics to all polymers e.g. in films.
N,N-bis-stearyl-ethylenediamine does not affect the transparency of polymers and acts as lubricant in a wide variety of polymers like PVC, PO, PS and engineering plastics.


N,N-bis-stearyl-ethylenediamine is used as defoamer/ anti-foaming agent and coating component of paper for paper-making industry.
Added in the manufacturing process of dope and oil paint to enhance salt mist and dampproof effect and to improve performance of paint remover.
Dispersing agent for masterbatch applications, preferably for engineering resins and PVC.


N,N-bis-stearyl-ethylenediamine provides typical slip and anti blocking characteristics to all polymers e.g. in films.
N,N-bis-stearyl-ethylenediamine is used in the following products: adhesives and sealants, lubricants and greases, coating products, polishes and waxes and washing & cleaning products.


N,N-bis-stearyl-ethylenediamine is used in the following products: washing & cleaning products, lubricants and greases, coating products, inks and toners and polishes and waxes.
N,N-bis-stearyl-ethylenediamine is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.


N,N-bis-stearyl-ethylenediamine is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.
N,N-bis-stearyl-ethylenediamine can help to increase the smoothness and fineness for insulator layer of electric power and cable.


N,N-bis-stearyl-ethylenediamine can decrease the viscosity of asphalt and improve it’s softening point and weathering resistance when added to asphalt.
N,N-bis-stearyl-ethylenediamine is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.


Because of its excellent lubricating properties N,N-bis-stearyl-ethylenediamine is widely used internally and/or externally in most plastics such as ABS, PS, PP etc.
N,N-bis-stearyl-ethylenediamine is also used as a release agents, antistats, and antifoaming agent.


As N,N-bis-stearyl-ethylenediamine has good wearable performance and smoothing performance, fits for improving polishing performance of lacquer, air release of surface with holes, N,N-bis-stearyl-ethylenediamine is also well used as dulling agent for polishing furniture and printing ink.
N,N-bis-stearyl-ethylenediamine is added to oil based defoamers to improve foam knock down.


N,N-bis-stearyl-ethylenediamine is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.
Slip- and anti-blocking agent for polyolefins and PVC, especially for film applications and also lubricant for wood plastic composites and plastics.


N,N-bis-stearyl-ethylenediamine is useed Anti-Blocking Agent, Release Agent, Slip Agent, Flow Promoter, and Hot-Melt Adhesive
N,N-bis-stearyl-ethylenediamine provides typical slip and anti blocking characteristics to all polymers.
Used as additive N,N-bis-stearyl-ethylenediamine can be incorporated directly into polymers to prevent any unwanted adhesion.


N,N-bis-stearyl-ethylenediamine is used Raw materials, Ethylenediamine Trap Stearic acid, Preparation Products, defoaming agent OTD
N,N-bis-stearyl-ethylenediamine is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.
N,N-bis-stearyl-ethylenediamine is used in powder metallurgy.


N,N-bis-stearyl-ethylenediamine can be found in industrial use: in processing aids at industrial sites, formulation in materials and as processing aid.
N,N-bis-stearyl-ethylenediamine is used in the following products: washing & cleaning products, lubricants and greases, coating products, inks and toners and polishes and waxes.


Adhesive pellets or film often develop adhesion between the polymer pellets or layers when exposed to elevated temperatures and pressures.
N,N-bis-stearyl-ethylenediamine is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.


N,N-bis-stearyl-ethylenediamine can also be used as a process aid, for example to improve dispersion of fillers.
N,N-bis-stearyl-ethylenediamine is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.


Because of it's excellent lubricating properties, N,N-bis-stearyl-ethylenediamine is widely used internally and/or externally in most plastics such as ABS, PS, PP etc.
Adhesive pellets or film often develop adhesion between the polymer pellets or layers when exposed to elevated temperatures and pressures.


N,N-bis-stearyl-ethylenediamine is used as lubricant in powder metallurgy (PM) steels to reduce the inter-particle and die-wall friction during pressing and hence improve powder compressibility and ejection of the component from the compaction tool.
N,N-bis-stearyl-ethylenediamine can help to increase the melting point of petroleum products; lubricant and corrosive agent of metal wire drawing.


N,N-bis-stearyl-ethylenediamine is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.


N,N-bis-stearyl-ethylenediamine is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits.
N,N-bis-stearyl-ethylenediamine is also used as release agents, antistatic agents, and antifoaming agents.


-Application of N,N-bis-stearyl-ethylenediamine:
· Internal and external lubricant for plastics - ABS, Polystyrene, and Phenol resin etc.
· External Lubricant for extrusion and injection of rigid or soft PVC
· Release and anti-blocking agent
· Dispersant agent for pigments


-Coatings and printing ink:
When manufacturing coating and painting, N,N-bis-stearyl-ethylenediamine can improve the effect of salt spray and moistureproof by adding it.
N,N-bis-stearyl-ethylenediamine can help to improve the paint stripper performance of paint when added, and to increase the leveling performance of baking enamel varnish.


-Chemical fiber:
N,N-bis-stearyl-ethylenediamine can improve heat and weather resistance performance of polyester and polyamide fiber, and has some anti-static effect.
-Pigment and filler:
N,N-bis-stearyl-ethylenediamine can be used as pigment dispersant of plastic , fiber, such as ABS, PS, polypropylene fibre and PET fiber and other color masterbatch.


-Pigment, filler dispersant:
*N,N-bis-stearyl-ethylenediamine is used as a pigment dispersant for plastic.
*Pigment dispersant for chemical fiber masterbatches, such as ABS, PS, polypropylene, polyester masterbatches.
*N,N-bis-stearyl-ethylenediamine can also be used as diffusion powder for plastic color matching.
*Depending on the amount of pigment and filler added, the addition amount is 0.5~5%.


-Rubber:
Synthetic resins and rubber such as Vinyl, polychloroprene, GRS (SBR) add 1~3% EBS to their emulsions, it has a good anti-viscosity and anti-caking effect, EBS is used in floor mats for automobiles, drainage pipes, and other rubber products to increase the effect of surface gloss.



-Paint, Ink:
*Adding 0.5~2% N,N-bis-stearyl-ethylenediamine can improve the effect of salt spray and moisture resistance in the manufacture of paint and lacquer.
*Adding N,N-bis-stearyl-ethylenediamine in the paint can improve the performance of the paint stripper and can improve the leveling of the baked enamel surface.
*N,N-bis-stearyl-ethylenediamine can be used as a matting agent in furniture polishing agents and printing ink.
*After micronization (particle size: d50 about 6μ, d 90 about 12μ), N,N-bis-stearyl-ethylenediamine has excellent anti-abrasion and smoothness and can be used in lacquer systems to improve polishability and degassing on a porous surface.


-Used as additive:
N,N-bis-stearyl-ethylenediamine can be incorporated directly into polymers to prevent any unwanted adhesion.
Adhesive pellets or film often develop adhesion between the polymer pellets or layers when exposed to elevated temperatures and pressures.
N,N-bis-stearyl-ethylenediamine is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.
N,N-bis-stearyl-ethylenediamine can also be used as a process aid, for example to improve dispersion of fillers.


-Plastic uses of N,N-bis-stearyl-ethylenediamine:
Lubricants inside or outside many plastics such as ABS, PS, AS, PVC, PE, PP, PVAC, cellulose acetate, nylon, phenolic resin and amino plastics.
N,N-bis-stearyl-ethylenediamine has a good surface quality and demoulding performance.


-Rubber:
Synthetic resin and rubber will have good anti-adhesive and anti-caking effect by adding N,N-bis-stearyl-ethylenediamine in their emulsion.
N,N-bis-stearyl-ethylenediamine has a good effect to the increase surface gloss when added to rubber products.


-Other uses of N,N-bis-stearyl-ethylenediamine:
*Melting point rising agent for petroleum products
*Lubricant and anti-corrosion agent for metal drawing
*Potting material for electrical components; defoaming agent and paper coating ingredient for paper industry
*N,N-bis-stearyl-ethylenediamine is used as a defoaming agent and permanent water pulling agent for dyeing works in textile dyeing and finishing
*Adding this product in asphalt can reduce the viscosity of asphalt and improve the softening point, water-resistance and weather resistance of asphalt.


-Powder Coating:
N,N-bis-stearyl-ethylenediamine can be used as flow additives for powder coatings.
-Hot-Melt Adhesive Applications of N,N-bis-stearyl-ethylenediamine:
*Release agent and flow promoter for all engineering resins, Styrenics and their copolymers.


-Applications of N,N-bis-stearyl-ethylenediamine:
*Release agent and flow promoter for all engineering resins, Styrenics and their copolymers
*Lubricant in powder metal molding, rubber, adhesives, coatings, wire drawing, wood plastic composite
*Defoamer in paper
*Lubricant for Polyacetals
*Water repellent for paper
*Intermediate for defoamers
*Delustering agent for furniture finishes and printing inks
*Dispersing agent for masterbatch applications, preferably for engineering resins and PVC
*Modifier in textile auxiliaries


-Consumer Goods:
*Appliances & Electronics
*Adhesives & Sealants: Industrial & *Assembly Adhesives
*Electronics Adhesives
*Industrial Manufacturing
*Healthcare & Pharma — Medical
*Medical Tapes & Adhesives
*Electrical & Electronics — Packaging & Assembly
*Adhesives & Sealants
*Adhesive & Sealant Type


-Mode of action:
N,N-bis-stearyl-ethylenediamine can be dispersed evenly through the polymer in the melt phase.
N,N-bis-stearyl-ethylenediamine migrates to the surface of the polymer where it forms a thin lubricating layer.
This layer reduces the coefficient of friction between surfaces and prevents any unwanted adhesion.


-Applications of N,N-bis-stearyl-ethylenediamine:
*Adhesives & sealants
*Composites
*Inks



BENEFITS of N,N-BIS-STEARYL-ETHYLENEDIAMINE:
-Excellent slip and anti-blocking properties when used in PVC, engeneering resins, PO film and compounds
-Good release properties in PVC and thermoplastics
-Improves flow of polymers
-No influence on transparency of polymers
-Wide food approval



PHYSICAL and CHEMICAL PROPERTIES of N,N-BIS-STEARYL-ETHYLENEDIAMINE:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 720.34 °C. @ 760.00 mm Hg (est)
Flash Point: 213.00 °F. TCC ( 100.70 °C. ) (est)
logP (o/w): 14.787 (est)
Soluble in: water, 2.049e-010 mg/L @ 25 °C (est)
Solubility: 0 ng/L at 25℃
Melting Point: 144-146 °C(lit.)
Formula: C38H76N2O2
Boiling Point: 720.3 °C at 760 mmHg
Molecular Weight: 593.034
Flash Point: 100.7 °C
Transport Information: N/A
Appearance: oily liquid
Safety: 26-36
Risk Codes: 36/37/38
CAS No.: 110-30-5
Density: 0.888 g/cm3
PSA: 58.20000
LogP: 12.52360

Appearance: Waxy Solid
Boiling Point: 720.3 °C
CAS Number: 110-30-5
Density: 0.88 g/cm3
EINECS Number: 203-755-6
IUPAC Name: N-[2-(Octadecanoylamino)Ethyl]Octadecanamide
InChI: 1S/C38H76N2O2/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-37(41)39-35-36-40-38(42)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-36H2,1-2H3,(H,39,41)(H,40,42)
InChIKey: RKISUIUJZGSLEV-UHFFFAOYSA-N
Melting Point: 144-146 °C
Molar Mass: 592.59 g/mol
Molecular Formula: C38H76N2O2
Refractive: 1.467 n/D
Solubility: Soluble In Ketones, Alcohols And Other Organic Solvents

Appearance: White, waxy crystals
Odor: Odourless
Melting point: 144 to 146 °C (291 to 295 °F; 417 to 419 K)
Flash point: 280 °C (536 °F; 553 K)
Physical state: Beads
Color: white
Odor: odorless
Melting point/range: 144 - 146 °C - lit.
Initial boiling point and boiling range: 260 °C at 1.013 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: ca.270 °C - DIN 51758
Autoignition temperature: ca.380 °C at 1.013 hPa - DIN 51794
Decomposition temperature: > 200 °C -
pH: No data available
Viscosity Viscosity, kinematic: No data available
Viscosity, dynamic: ca.10 mPa.s at 150 °C
Water solubility at 20 °C: insoluble

Partition coefficient: n-octanol/water log Pow: 13,98 at 25 °C
Vapor pressure: Not applicable
Density: 1 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 720.34 °C. @ 760.00 mm Hg (est)
Flash Point: 213.00 °F. TCC ( 100.70 °C. ) (est)
logP (o/w): 14.787 (est)
Soluble in: water, 2.049e-010 mg/L @ 25 °C (est)

Molecular Weight: 593.0
XLogP3-AA: 15.7
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 35
Exact Mass: 592.59067967
Monoisotopic Mass: 592.59067967
Topological Polar Surface Area: 58.2 Ų
Heavy Atom Count: 42
Formal Charge: 0
Complexity: 503
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Melting point: 144-146 °C(lit.)
Boiling point: 646.41°C (rough estimate)
Density: 1 g/cm3 (20℃)
vapor pressure: 0.000023 Pa (20 °C)
refractive index: 1.4670 (estimate)
Flash point: 280℃
storage temp.: 2-8°C
solubility: ketones, alcohols and aromatic solvents at their boiling points: soluble
pka: 15.53±0.46(Predicted)
form: beads
Appearance: Powdery
Smell: No smell
Color (Gardner): ≤3#
Melting Point (℃): 141.5-146.5
Acid Value (mgKOH/g): ≤7.50
Amine value (mgKOH/g): ≤2.50
Moisture (wt%): ≤0.30
Mechanical impurity: Φ0.1-0.2mm(individual/10g)



FIRST AID MEASURES of N,N-BIS-STEARYL-ETHYLENEDIAMINE:
-Description of first-aid measures:
*After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*After swallowing:
Make victim drink water (two glasses at most).
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of N,N-BIS-STEARYL-ETHYLENEDIAMINE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of N,N-BIS-STEARYL-ETHYLENEDIAMINE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of N,N-BIS-STEARYL-ETHYLENEDIAMINE:
-Control parameters
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of N,N-BIS-STEARYL-ETHYLENEDIAMINE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of N,N-BIS-STEARYL-ETHYLENEDIAMINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



SYNONYMS:
n,n'-ethylene bis(stearamide)
N,N'-Ethylenedi(stearamide)
N,N'-Ethylene bis(octadecanamide)
1,2-Bis(octadecanamido)ethane
N,N'-Ethylene distearylamide
ABRIL WAX 10DS
ACRAWAX CT
ACROWAX C
ADVAWACHS 280
ADVAWAX
ADVAWAX 275
ADVAWAX 280
ARMOWAX EBS-P
CARLISLE 280
CARLISLE WAX 280
CHEMETRON 100
KEMAMIDE W 40
LUBROL EA
MICROTOMIC 280
N,N'-DISTEAROYLETHYLENEDIAMINE
1,2-Bis(octadecanamido)ethane
110-30-5
8032-03-9
12687-19-3
12764-90-8
51796-18-0
55598-87-3
58051-94-8
130253-72-4
195329 -73-8
434671_ALDRICH
ABRIL WAX 10DS
ACRAWAX CT
ACROWAX C
ADVAWACHS 280
ADVAWAX
ADVAWAX 275
ADVAWAX 280
AI3-08515
ARMOWAX EBS-P
C38H76N2O2
CARLISLE 280
CARLISLE WAX 280
CCRIS 2293
CHEMETRON 100
EINECS 203-755-6
Ethylenebis(stearylamide)
Ethylenebisoctadecanamide
Ethylenebisstearamide
Ethylenebisstearoamide
Ethylenediamine bisstearamide
Ethylenediamine steardiamide
Ethylene distearamide
HSDB 5398
KEMAMIDE W 40
LS-178738
LUBROL EA
MICROTOMIC 280
N,N-ethylenedi(stearamide)
1,2-distearamidoethane
N,N-Ethylenebisoctadecanamide
N,N'-ethylene bis-stearamide
N,N'-ethane-1,2-diyldioctadecanamide
2,5-dihexadecylhexanediamide
1,2-Bis(stearoylamino) ethane
N,N′-1,2-Ethanediylbisoctadecanamide
N,N′-Ethylenedi(stearamide)
Ethylene distearylamide
N,N′-(Ethane-1,2-diyl)di(octadecanamide)
ETHYLENE-BIS-STEARAMIDE
waxc
EBSA
advawax
acrawaxc
acrowaxc
lubrolea
5-AC-13C4
acrawaxct
110-30-5
N,N'-Ethylenebis(stearamide)
Plastflow
Ethylene distearamide
N,N'-(Ethane-1,2-diyl)distearamide
Advawax
Acrowax C
Acrawax CT
Lubrol EA
Ethylenedistearamide
Microtomic 280
Advawachs 280
Ethylenebis(stearylamide)
Abril wax 10DS
Carlisle 280
Nopcowax 22-DS
Ethylenebisstearoamide
Advawax 275
Advawax 280
Carlisle Wax 280
Armowax ebs-P
Ethylenebis(stearamide)
Octadecanamide, N,N'-1,2-ethanediylbis-
N,N'-Ethylenebisoctadecanamide
1,2-Bis(octadecanamido)ethane
Chemetron 100
N,N'-ETHYLENE DISTEARYLAMIDE
N,N'-Ethylenedistearamide
Ethylenediamine steardiamide
Ethylenediamine bisstearamide
N,N'-Distearoylethylenediamine
Ethylenebisstearamide
N,N'-Ethylenebisstearamide
NN'-Ethylenebis(stearamide)
Stearic acid, ethylenediamine diamide
Ethylenebisoctadecanamide
Octadecanamide, N,N'-ethylenebis-
UNII-603RP8TB9A
N-[2-(octadecanoylamino)ethyl]octadecanamide
N,N-Ethylenebis(stearamide)
603RP8TB9A
N,N'-ethane-1,2-diyldioctadecanamide
Acrawax C
Kemamide W 40
N,N'-Ethylenedi(stearamide)
WAX C
N,N-Ethylenebisstearamide
CCRIS 2293
ethylene bisstearamide
HSDB 5398
Ethylene bis stearamide
Ethylene bis(stearamide)
EINECS 203-755-6
NSC 83613
N,N'-Ethylene bisstearamide
AI3-08515
N,N'-ethylene-bis-stearic amide
Abluwax EBS
Armowax EBS
Dorset WAX
C38H76N2O2
N,N'-ethylenebis
Glycowax 765
Kemamide W-39
Kemamide W-40
N,N'-1,2-Ethanediylbisoctadecanamide
Uniwax 1760
EC 203-755-6
Ethylene Bis Stearamide SF
SCHEMBL19975
Octadecanamide,N'-ethylenebis-
DTXSID4026840
NSC83613
MFCD00059224
NSC-83613
ZINC85733714
AKOS015915120
Octadecanamide,N'-1,2-ethanediylbis-
DS-6811
E0243
FT-0629590
V0595
D70357
N,N'-Ethylenebis(stearamide), beads, A802179
Q5404472
W-108690
2,5-dihexadecylhexanediamide
N,N'-(Ethane-1,2-diyl)distearamide
Plastic additive 03, European Pharmacopoeia (EP)
n,n'-ethylenebisoctadecanamide (mixture of fatty acid amides) (consists of c14, c16 and c18)
N,N'-Ethylenedi(stearamide)
1,2-Bis(stearoylamino) ethane
N,N′-1,2-Ethanediylbisoctadecanamide
Ethylene distearylamide
Ethylene bisstearamide
Ethylene distearamide
EBS
1,2- Bis(octadecanamido)ethane
Ethylenebisoctadecanamide
Ethylenebis(stearylamide)
Ethylenediamine bisstearamide
N-[2-(octadecanoylamino)ethyl]octadecanamide
N-(2-stearamidoethyl)stearamide
N,N'-Distearoylethylenediamine
N,N'-ethane-1,2-diyldioctadecanamide
N,N'-Ethylenedistearamide
n,n'-Ethylene distearylamide
Octadecanamide
N,N'-1,2-Ethanediylbisoctadecanamide
N,N'-DISTEAROYLETHYLENEDIAMINE
N,N'-ethane-1,2-diyldioctadecanamide
N,N'-Ethyl don't bis(octadecanamide)
n,n'-ethylene bis(stearamide)
N,N'-ETHYLENEBIS(STEARAMIDE)
N,N'-Ethylene bisstearamide
N,N'-Ethylenebisstearamide
N,N'-Ethylenedi(stearamide)
N,N'- ETHYLENEDISTEARAMIDE
N,N'-Ethylene distearylamide
N-(2-stearamidoethyl)stearamide
N-[2-(octadecanoylamino)ethyl]octadecanamide
Nopcowax 22-DS
NSC 83613
NSC83613
Octadecanamide, N,N'-1,2-ethanediylbis-
OCTADECANAMIDE, N,N'-ETHYLENEBIS-
Octadecanamide, N,N'-ethylenebis- (8CI)
PLASTFLOW
Stearic acid, ethylenediamine diamide
Octadecanamide,N,N'-ethylenebis- (6CI,7CI,8CI)
1,2-Bis(octadecanamido)ethane
1,2-Ethylenebis(stearamide)
Alflow H 50T
Alflow H 50TF
Armoslip EBS
Armowax EBS
ArmowaxEBS Powder
Armowax EBS-B
Armowax EBS-P
Atmer SA 1760
Banlub N 18
Bis(stearoyl)ethylenediamide
C Wax
Carlisle 280
Carlisle Wax 280
Ceridust3910
Chemetron 100
Croda 212
Crodamide EBS
Denon PB 1239
Dorset Wax
EB-FF
EB-P
EBA 200
EBS
EBS-C
EBS-SF
Ethylenebis[stearamide]
Ethylenebis[stearic acid amide]
Ethylenediamine bis(stearamide)
Fatty AmideEB-G
H 50P
H 50T
Hidorin B 961
Hoechst Wax C
Hostalub FA 1
Hymicron G 110
JHE 341
Kao Wax EB
Kao Wax EB-F
Kao Wax EB-FF
Kao Wax EB-G
N,N'-Bis(octadecanoyl)ethylenediamine
N,N'-Bis(stearoyl)ethylenediamine
N,N'-Distearoylethylenediamine
N,N'-Ethylene distearylamide
N,N'-Ethylenebis(octadecanamide)
N,N'-Ethylenebis(stearic amide)
N,N'-Ethylenebis(stearylamide)
N,N'-Ethylenedistearamide
EBS
N,N'-1,2-Ethanediylbisoctadecanamide
N,N'-Ethylenedi(Stearamide)
1,2-Bis(Stearoylamino) Ethane
N,N'-Ethylenedi(Stearamide)
Ethylene Distearylamide
Ethylene bisstearamide
Ethylene distearamide
EBS
1,2- Bis(octadecanamido)ethane
Ethylenebisoctadecanamide
Ethylenebis(stearylamide)
Ethylenediamine bisstearamide
N-[2-(octadecanoylamino)ethyl]octadecanamide
N-(2-stearamidoethyl)stearamide
N,N'-Distearoylethylenediamine
N,N'-ethane-1,2-diyldioctadecanamide
N,N'-Ethylenedistearamide
n,n'-Ethylene distearylamide
Octadecanamide



N,N-DIETHYL-2-AMINOETHANOL
DESCRIPTION:
N,N-DIETHYL-2-AMINOETHANOL (DEEA) is a tertiary alkanolamine multi-component aqueous solvent.
N,N-DIETHYL-2-AMINOETHANOL has a high chemical stability and resistance against degradation.
N,N-DIETHYL-2-AMINOETHANOL is used to prepare quaternary ammonium salts.
These salts are widely used as phase transfer catalysts to promote reactions between immiscible phases.

CAS Number: 100-37-8
EC Number: 202-845-2
Linear Formula:(C2H5)2NCH2CH2OH

SYNONYM(S) OF N,N-DIETHYL-2-AMINOETHANOL:
N,N-DIETHYL-2-AMINOETHANOL, DEAE, DEEA N,N-DIETHYL-2-AMINOETHANOL,N,N-DIETHYL-2-AMINOETHANOL,N,N-DIETHYL-2-AMINOETHANOL,N,N-Diethyl-2-aminoethanol,N,N-DIETHYL-2-AMINOETHANOL,Diethyl(2-hydroxyethyl)amine,(2-Hydroxyethyl)diethylamine,2-Diethylaminoethyl alcohol,2-Hydroxytriethylamine,N,N-DIETHYL-2-AMINOETHANOL,2-HYDROXYTRIETHYLAMINE,BETA-DIETHYLAMINOETHYL ALCOHOL,DIETHYL ETHANOLAMINE,DIETHYLAMINO-2 ETHANOL,N,N-DIETHYL-2-AMINOETHANOL,DIETHYLETHANOLAMINE,DIETHYLETHANOLAMINE (DEEA),N,N-DIETHYL-2-AMINOETHANOL,N,N-DIETHYL-2-AMINOETHANOL,N,N-DIETHYL-2-AMINOETHANOL,N,N-N,N-DIETHYL-2-AMINOETHANOL,N,N-DIETHYL-2-AMINOETHANOL,N,N-DIETHYL-2-AMINOETHANOL,2-(dimethylamino)ethanol hydrochloride,2-(N,N-dimethylamino)ethanol hydrochloride,N,N-DIETHYL-2-AMINOETHANOL,N,N-DIETHYL-2-AMINOETHANOL hydrochloride,N,N-DIETHYL-2-AMINOETHANOL hydrochloride, 14C-labeled,N,N-DIETHYL-2-AMINOETHANOL sulfate (2:1),N,N-DIETHYL-2-AMINOETHANOL tartrate,N,N-DIETHYL-2-AMINOETHANOL, sodium salt,DEAE,deanol hydrochloride,N,N-DIETHYL-2-AMINOETHANOL,diethylethanolamine,ethanol, 2-(dimethylamino)-, hydrochloride (1:1),ethanol, 2-dimethylamino-, hydrochloride,N,N-DIETHYL-2-AMINOETHANOL,N,N-DIETHYL-2-AMINOETHANOL,N,N-DIETHYL-2-AMINOETHANOL,N,N-DIETHYL-2-AMINOETHANOL,100-37-8,N,N-DIETHYL-2-AMINOETHANOL,Diethylethanolamine,DEAE,N,N-DIETHYL-2-AMINOETHANOL,N,N-DIETHYL-2-AMINOETHANOL,N,N-Diethyl-2-aminoethanol,(2-Hydroxyethyl)diethylamine,Diethyl(2-hydroxyethyl)amine,2-(Diethylamino)Ethan-1-Ol,Diethylmonoethanolamine,2-Hydroxytriethylamine,Pennad 150,Diaethylaminoaethanol,2-(N,N-Diethylamino)ethanol,N,N-Diethylmonoethanolamine,N,N-Diethyl-2-hydroxyethylamine,beta-N,N-DIETHYL-2-AMINOETHANOL,beta-Hydroxytriethylamine,2-(Diethylamino)ethyl alcohol,Diethylamino ethanol,N-N,N-DIETHYL-2-AMINOETHANOL,2-N-N,N-DIETHYL-2-AMINOETHANOL,diethyl ethanolamine,DEEA,beta-Diethylaminoethyl alcohol,2-diethylamino-ethanol,N-N,N-DIETHYL-2-AMINOETHANOL,N,N-Diethyl-N-(beta-hydroxyethyl)amine,NSC 8759,N,N-N,N-DIETHYL-2-AMINOETHANOL,2-(diethylamino)-ethanol,2-N-N,N-DIETHYL-2-AMINOETHANOL,.beta.-N,N-DIETHYL-2-AMINOETHANOL,ETHANOL,2-DIETHYLAMINO,S6DL4M053U,beta-(Diethylamino)ethyl alcohol,DTXSID5021837,CHEBI:52153,.beta.-(Diethylamino)ethyl alcohol
NSC-8759,N,N-Diethyl-N-(.beta.-hydroxyethyl)amine,DTXCID401837,ethane, 1-diethylamino-2-hydroxy-,CAS-100-37-8,Diaethylaminoaethanol [German],CCRIS 4793,HSDB 329,EINECS 202-845-2,UN2686,UNII-S6DL4M053U,-diethylamino,AI3-16309,2-Diethylamino,Diathylaminoathanol,Diethylamlnoethanol,MFCD00002850,N, N-Diethylethanolamine,beta-N,N-DIETHYL-2-AMINOETHANOL,N,N-diethyl ethanol amine,N,N-DIETHYL-2-AMINOETHANOL [UN2686] [Corrosive],.beta.-Hydroxytriethylamine,EC 202-845-2,SCHEMBL3114,N,N-DIETHYL-2-AMINOETHANOL, 9CI,CHEMBL1183,Diaethylaminoaethanol(german),2-(diethylamino)-1-ethanol,MLS002174251,2-(N,N-diethylamino)-ethanol,N,N-DIETHYL-2-AMINOETHANOL, 99%,N,N-DIETHYL-2-AMINOETHANOL [HSDB],N-(beta-hydroxyethyl)diethylamine,NSC8759,HMS3039I08,N,N-DIETHYL-2-AMINOETHANOL, >=99%,N,N-DIETHYL-2-AMINOETHANOL [MART.],WLN: Q2N2 & 2,N,N-DIETHYL-2-AMINOETHANOL [WHO-DD],N-(hydroxyethyl)-N,N-diethyl amine,Tox21_201463,Tox21_300037,BBL012211,STL163552,N,N-DIETHYL-2-AMINOETHANOL [MI],N,N-DIETHYL-2-AMINOETHANOL, >=99.5%,AKOS000119883,UN 2686,NCGC00090925-01,NCGC00090925-02,NCGC00090925-03,NCGC00253920-01,NCGC00259014-01,A 22,BP-20552,SMR001261425,VS-03234,DB-012722,D0465,NS00006343,N,N-DIETHYL-2-AMINOETHANOL [UN2686] [Corrosive],D88192,N,N-DIETHYL-2-AMINOETHANOL, purum, >=99.0% (GC),Q209373,N,N-DIETHYL-2-AMINOETHANOL 100 microg/mL in Acetonitrile,J-520312,Diethyl ethanolamine N,N-DIETHYL-2-AMINOETHANOL 2-Hydroxytriethylamine,InChI=1/C6H15NO/c1-3-7(4-2)5-6-8/h8H,3-6H2,1-2H


N,N-DIETHYL-2-AMINOETHANOL appears as a colorless liquid.
N,N-DIETHYL-2-AMINOETHANOL has Flash point 103-140 °F.
N,N-DIETHYL-2-AMINOETHANOL is Less dense than water.

Vapors of N,N-DIETHYL-2-AMINOETHANOL is heavier than air.
N,N-DIETHYL-2-AMINOETHANOL Produces toxic oxides of nitrogen during combustion.
N,N-DIETHYL-2-AMINOETHANOL Causes burns to the skin, eyes and mucous membranes.

N,N-DIETHYL-2-AMINOETHANOL is a member of the class of ethanolamines that is aminoethanol in which the hydrogens of the amino group are replaced by ethyl groups.
N,N-DIETHYL-2-AMINOETHANOL is a member of ethanolamines, a tertiary amino compound and a primary alcohol.
N,N-DIETHYL-2-AMINOETHANOL is functionally related to an ethanolamine.
N,N-DIETHYL-2-AMINOETHANOL derives from a hydride of a triethylamine.


Diethylethanolamine (DEAE) is the organic compound with the molecular formula (C2H5)2NCH2CH2OH.
A colorless liquid, is used as a precursor in the production of a variety of chemical commodities such as the local anesthetic procaine.


APPLICATIONS OF N,N-DIETHYL-2-AMINOETHANOL:
N,N-DIETHYL-2-AMINOETHANOL (DEEA) can be used as a co-solvent with methyldiethanolamine (MDEA) and sulfolane to investigate the CO2 absorption and desorption behavior in aqueous solutions.
Additionally, DEAE is used to prepare N-substituted glycine derivatives and these compounds are used in the synthesis of peptides and proteins.

N,N-DIETHYL-2-AMINOETHANOL is used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging oxygen.
N,N-DIETHYL-2-AMINOETHANOL reacts with 4-aminobenzoic acid to make procaine.
N,N-DIETHYL-2-AMINOETHANOL is a precursor for DEAE-cellulose resin, which is commonly used in ion exchange chromatography.
N,N-DIETHYL-2-AMINOETHANOL can decrease the surface tension of water when the temperature is increased.[3]
Solutions of N,N-DIETHYL-2-AMINOETHANOL absorb carbon dioxide (CO2).

N,N-DIETHYL-2-AMINOETHANOL can be used as a precursor chemical to procaine.
N,N-DIETHYL-2-AMINOETHANOL is used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging oxygen.
N,N-DIETHYL-2-AMINOETHANOL is used for the synthesis of drugs in the pharmaceutical industry and as a catalyst for the synthesis of polymers in the chemical industry.
N,N-DIETHYL-2-AMINOETHANOL is also used as a pH stabilizer.



USE AND EMISSION SOURCES 1 2 3 4:
N,N-DIETHYL-2-AMINOETHANOL is used as an intermediate in the manufacture of emulsifying agents, specialty soaps and other chemicals for applications in:
Pharmaceutical industry
pesticides
the paper
leather products
plastics
anti-rust products
the paintings
the textile
cosmetics
surface coatings...


PREPARATION OF N,N-DIETHYL-2-AMINOETHANOL:
N,N-DIETHYL-2-AMINOETHANOL is prepared commercially by the reaction of diethylamine and ethylene oxide.[4]
(C2H5)2NH + cyclo(CH2CH2)O → (C2H5)2NCH2CH2OH
N,N-DIETHYL-2-AMINOETHANOL is also possible to prepare it by the reaction of diethylamine and ethylene chlorohydrin.[5


CHEMICAL AND PHYSICAL PROPERTIES OF N,N-DIETHYL-2-AMINOETHANOL:
vapor density
4.04 (vs air)
Quality Level
100
vapor pressure
1 mmHg ( 20 °C)
Assay
≥99.5%
expl. lim.
11.7 %
refractive index
n20/D 1.441 (lit.)
bp
161 °C (lit.)
density
0.884 g/mL at 25 °C (lit.)
SMILES string
CCN(CC)CCO
InChI
1S/C6H15NO/c1-3-7(4-2)5-6-8/h8H,3-6H2,1-2H3
InChI key
BFSVOASYOCHEOV-UHFFFAOYSA-N
Molecular Weight:
117.19
Beilstein:
741863
Chemical formula C6H15NO
Molar mass 117.192 g•mol−1
Appearance Colourless liquid
Odor Ammoniacal
Density 884 mg mL−1
Melting point −70 °C; −94 °F; 203 K[1]
Boiling point 161.1 °C; 321.9 °F; 434.2 K
Solubility in water miscible[1]
log P 0.769
Vapor pressure 100 Pa (at 20 °C)
Refractive index (nD) 1.441–1.442
CAS number 100-37-8
CE index number 603-048-00-6
CE number 202-845-2
Hill formula C₆H₁₅NO
Chemical formula (C₂H₅)₂NCH₂CH₂OH
Molar Mass 117.19 g/mol
Code SH 2922 19 52
Boiling point 163 °C (1013 hPa)
Density 0.88 g/cm3 (20 °C)
Explosion limit 0.7%(V)
Flash point 50 °C
Ignition temperature 270 °C
Fusion point -68 °C
pH value 11.5 (100 g/l, H₂O, 20 °C)
Vapor pressure 1 hPa (20 °C)
Assay (GC, area%) ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C) 0.883 - 0.885
Water (K. F.) ≤ 0.30 %
Identity (IR) passes test
Molecular Weight
117.19 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
XLogP3-AA
0.3
Computed by XLogP3 3.0 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
1
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
2
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
4
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
117.115364102 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
117.115364102 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
23.5Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
8
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
43.8
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
0
Computed by PubChem
Undefined Atom Stereocenter Count
0
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
1
Computed by PubChem
Compound Is Canonicalized
Yes
vapor pressure
1.9 hPa ( 20 °C)
Quality Level
200
Assay
≥99.0% (GC)
form
liquid
autoignition temp.
270 °C
potency
1300 mg/kg LD50, oral (Rat)
1109 mg/kg LD50, skin (Rabbit)

expl. lim.
0.7 % (v/v)
pH
11.5 (20 °C, 100 g/L in H2O)
bp
163 °C/1013 hPa
mp
-68 °C
transition temp
flash point 51 °C
density
0.88 g/cm3 at 20 °C
storage temp.
2-30°C
InChI
1S/C6H15NO/c1-3-7(4-2)5-6-8/h8H,3-6H2,1-2H3
InChI key
BFSVOASYOCHEOV-UHFFFAOYSA-N
Storage Temperature
RT
European Com.#
202-845-2
Hazmat Ship
Check subsku for hazmat
Purity
>99%
Appearance color
Clear, colorless
Appearance form
Liquid
Molecular Formula
C6H15NO
Molecular Weight
117.19
Density
0.884 g/mL at 25°C
Melting point
-70°C
Boiling point
161°C
Solubility (@ RT)
Solubility in water: Soluble
Solubility in other solvents: Soluble in alcohol, ether and benzene
Melting Point -70°C
Density 0.883
pH 11.5
Boiling Point 161°C to 163°C
Flash Point 52°C (125°F)
Odor Amine-like
Linear Formula (CH3CH2)2NCH2CH2OH
Refractive Index 1.4415
Quantity 1000 mL
UN Number UN2686
Beilstein 741863
Sensitivity Air and light sensitive; Hygroscopic
Merck Index 14,3112
Solubility Information It is miscible in water.
Molecular Weight (g/mol) 117.192
Formula Weight 117.19
Percent Purity 99%
Chemical Name or Material N,N-DIETHYL-2-AMINOETHANOL



SAFETY INFORMATION ABOUT N,N-DIETHYL-2-AMINOETHANOL
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.



N,N-DIETHYLETHANAMINE (TRIETHYLAMINE)
N,N-Diethylethanamine (Triethylamine) is the chemical compound with the formula N(CH2CH3)3
N,N-Diethylethanamine (Triethylamine) is commonly abbreviated Et3N.
N,N-Diethylethanamine (Triethylamine) is a colourless volatile liquid


CAS NUMBER: 121-44-8

EC NUMBER: 204-469-4

MOLECULAR FORMULA: C6H15N

MOLECULAR WEIGHT: 101.193 g/mol

IUPAC NAME: N,N-Diethylethanamine


N,N-Diethylethanamine (Triethylamine) is also abbreviated TEA
N,N-Diethylethanamine (Triethylamine) has a strong fishy odor reminiscent of ammonia.
Like diisopropylethylamine (Hünig's base), N,N-Diethylethanamine (Triethylamine) is commonly employed in organic synthesis, usually as a base.

N,N-Diethylethanamine (Triethylamine) is also useful in dehydrohalogenation reactions and Swern oxidations.
N,N-Diethylethanamine (Triethylamine) is used to give salts of various carboxylic acid-containing pesticides, e.g. Triclopyr and 2,4-dichlorophenoxyacetic acid

Synthesis and Properties:
N,N-Diethylethanamine (Triethylamine) is prepared by the alkylation of ammonia with ethanol:

NH3 + 3 C2H5OH → N(C2H5)3 + 3 H2O

The pKa of protonated N,N-Diethylethanamine (Triethylamine) is 10.75, and it can be used to prepare buffer solutions at that pH.
N,N-Diethylethanamine (Triethylamine) is a colorless
N,N-Diethylethanamine (Triethylamine) is hygroscopic powder, which decomposes when heated to 261 °C.

N,N-Diethylethanamine (Triethylamine) is useful in reverse phase chromatography, often in a gradient to purify nucleotides and other biomolecules.
N,N-Diethylethanamine (Triethylamine) is in the liquid state at room temperature, and it appears as a volatile, colourless liquid.

N,N-Diethylethanamine (Triethylamine) is soluble in water to the extent of 112.4 g/L at 20 °C.
N,N-Diethylethanamine (Triethylamine) is also miscible in common organic solvents, such as acetone, ethanol, and diethyl ether.

Laboratory samples of N,N-Diethylethanamine (Triethylamine) can be purified by distilling from calcium hydride.
In alkane solvents N,N-Diethylethanamine (Triethylamine) is a Lewis base that forms adducts with a variety of Lewis acids, such as I2 and phenols.
Owing to its steric bulk, N,N-Diethylethanamine (Triethylamine) forms complexes with transition metals reluctantly.

N,N-Diethylethanamine (Triethylamine) is slightly water-soluble.
N,N-Diethylethanamine (Triethylamine) is a colourless, odourless, and hygroscopic powder.

APPLICATIONS:
N,N-Diethylethanamine (Triethylamine) is commonly employed in organic synthesis as a base.
For example, N,N-Diethylethanamine (Triethylamine) is commonly used as a base during the preparation of esters and amides from acyl chlorides
Such reactions lead to the production of hydrogen chloride which combines with triethylamine to form the salt triethylamine hydrochloride, commonly called triethylammonium chloride.
Hydrogen chloride may then evaporate from the reaction mixture, which drives the reaction. (R, R' = alkyl, aryl):

R2NH + R'C(O)Cl + Et3N → R'C(O)NR2 + Et3NH+Cl−

Like other tertiary amines, N,N-Diethylethanamine (Triethylamine) catalyzes the formation of urethane foams and epoxy resins.
N,N-Diethylethanamine (Triethylamine) is also useful in dehydrohalogenation reactions and Swern oxidations.

N,N-Diethylethanamine (Triethylamine) is readily alkylated to give the corresponding quaternary ammonium salt:

RI + Et3N → Et3NR+I−

N,N-Diethylethanamine (Triethylamine) is mainly used in the production of quaternary ammonium compounds for textile auxiliaries and quaternary ammonium salts of dyes.
N,N-Diethylethanamine (Triethylamine) is also a catalyst and acid neutralizer for condensation reactions and is useful as an intermediate for manufacturing medicines, pesticides and other chemicals.

N,N-Diethylethanamine (Triethylamine) is used as an ion-interaction reagent in ion interaction chromatography, due to their amphiphilic properties.
Unlike quaternary ammonium salts, N,N-Diethylethanamine (Triethylamine) is much more volatile, therefore mass spectrometry can be used while performing analysis.

N,N-Diethylethanamine (Triethylamine) is a tertiary amine that is ammonia in which each hydrogen atom is substituted by an ethyl group.
N,N-Diethylethanamine (Triethylamine) is an organic compound having the chemical formula N(CH2CH2OH)3.
N,N-Diethylethanamine (Triethylamine) is commonly employed in organic synthesis as a base.

N,N-Diethylethanamine (Triethylamine) is used as a base during the preparation of esters and amides from acyl chlorides.
N,N-Diethylethanamine (Triethylamine) is used in the synthesis reactions in organic chemistry as a base.

N,N-Diethylethanamine (Triethylamine) is useful in the production of quaternary ammonium compounds for the textile industry.
N,N-Diethylethanamine (Triethylamine) is useful as an intermediate for manufacturing medicines, pesticides, etc.

N,N-Diethylethanamine (Triethylamine) is used cosmetically to improve skin elasticity.
N,N-Diethylethanamine (Triethylamine) is used in polymerization inhibitors

N,N-Diethylethanamine (Triethylamine) is an organic base used in organic synthesis.
N,N-Diethylethanamine (Triethylamine) is a benzimidazole derivative that inhibits phosphodiesterases

N,N-Diethylethanamine (Triethylamine) is a tertiary amine that is ammonia in which each hydrogen atom is substituted by an ethyl group.
N,N-Diethylethanamine (Triethylamine) is a colourless volatile liquid with a strong fishy odor reminiscent of ammonia.


PHYSICAL PROPERTIES:

-Molecular Weight: 102.20 g/mol

-Exact Mass: 102.128274515 g/mol

-Monoisotopic Mass: 102.128274515 g/mol

-Topological Polar Surface Area: 3.2Ų

-Color: Colourless

-Form: Liquid

-Odor: Fishy, Ammoniacal

-Density: 0.7255 g mL−1

-Melting Point: −114.70 °C; −174.46 °F; 158.45 K

-Boiling Point: 88.6 to 89.8 °C; 191.4 to 193.5 °F; 361.7 to 362.9 K

-LogP: 1.647

-Vapor Pressure: 6.899–8.506 kPa

-Henry's Law Constant (kH): 66 μmol Pa−1 kg−1

-Acidity (pKa): 10.75

-Magnetic Susceptibility (χ): -81.4·10−6 cm3/mol

-Refractive Index (nD): 1.401


N,N-Diethylethanamine (Triethylamine) is the chemical compound with the formula N(CH2CH3)3
N,N-Diethylethanamine (Triethylamine) is commonly abbreviated Et3N.

N,N-Diethylethanamine (Triethylamine) is a commonly encountered in organic synthesis probably because it is the simplest symmetrically trisubstituted amine, i.e. a tertiary amine, that is liquid at room temperature.
N,N-Diethylethanamine (Triethylamine) possesses a strong fishy odor reminiscent of ammonia.

N,N-Diethylethanamine (Triethylamine) is a widely used relative of triethylamine.
N,N-Diethylethanamine (Triethylamine) is also the smell of the hawthorn plant, and semen, among others


CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 0

-Hydrogen Bond Acceptor Count: 1

-Rotatable Bond Count: 3

-Heavy Atom Count: 7

-Formal Charge: 0

-Complexity: 25.7

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 2

-Compound Is Canonicalized: Yes


N,N-Diethylethanamine (Triethylamine) is an aliphatic amine.
N,N-Diethylethanamine (Triethylamine) can be produced by the alkylation of ammonia with ethanol.

The pKa of this liquid is about 10.75 so, N,N-Diethylethanamine (Triethylamine) can be used for the preparation of buffer solutions around pH 10.75.
N,N-Diethylethanamine (Triethylamine) is slightly water-soluble.

However, N,N-Diethylethanamine (Triethylamine) is miscible with some organic solvents as well. e.g. acetone, ethanol, etc.
N,N-Diethylethanamine (Triethylamine) is a colourless, odourless, and hygroscopic powder.

There are many important applications of N,N-Diethylethanamine (Triethylamine).
Commonly, N,N-Diethylethanamine (Triethylamine) is used in the synthesis reactions in organic chemistry as a base.
E.g. preparation of esters, amides from acyl chlorides.

Furthermore, N,N-Diethylethanamine (Triethylamine) is useful in the production of quaternary ammonium compounds for the textile industry.
N,N-Diethylethanamine (Triethylamine) is also useful as a catalyst and an acid neutralizer for condensation reactions.
Moreover, N,N-Diethylethanamine (Triethylamine) is useful as an intermediate for manufacturing medicines, pesticides, etc.

N,N-Diethylethanamine (Triethylamine) is an organic compound having the chemical formula N(CH2CH2OH)3.
N,N-Diethylethanamine (Triethylamine) contains three alcohol groups attached to a central nitrogen atom.

Therefore, we can classify N,N-Diethylethanamine (Triethylamine) as a triamine and as a triol.
N,N-Diethylethanamine (Triethylamine) occurs as a colourless and viscous liquid at room temperature.
However, if N,N-Diethylethanamine (Triethylamine) contains impurities, this liquid appears in yellow colour.

N,N-Diethylethanamine (Triethylamine) appears as a clear colorless liquid with a strong ammonia to fish-like odor.
N,N-Diethylethanamine (Triethylamine)'s flash point is 20 °F.

N,N-Diethylethanamine (Triethylamine) is less dense (6.1 lb / gal) than water.
N,N-Diethylethanamine (Triethylamine)'s vapors heavier than air.
N,N-Diethylethanamine (Triethylamine) is a tertiary amine that is ammonia in which each hydrogen atom is substituted by an ethyl group.


SYNONYMS:

N,N-diethylethanamine;hydron
17440-81-2
TEA
Ethanamine, N,N-diethyl-, conjugate acid
Ethanamine, N,N-diethyl-, compd. with borin
N,N-Diethylethanamine - borinine
SCHEMBL1334882
Ethanamine, N,N-diethyl-, conjugate acid
Ethanamine, N,N-diethyl-, compd. with borin (1:1)
N,N-Diethylethanamin -borinin (1:1)
N,N-Diethylethanamine - borinine (1:1)
N,N-Diéthyléthanamine - borinine (1:1)
TETN
Triethyl Amine
ethanamine
N,N-diethylethanaminium bromide
N,N-diethylethanamine sulfate
N,N-diethylethanamine acetate (1:1)
N,N-diethylethanaminium
N,N-diethylethanamine sulfate (1:1)
(C2H5)3N
Ethanamine, N,N-diethyl-, conjugate acid
Ethanamine, N,N-diethyl-, compd. with borin
N,N-Diethylethanamin -borinin (1:1)
N,N-Diethylethanamine - borinine
(diethylamino)ethane
N,N,N-triethylamine
N,N-Diethylethanamine
NEt3
TRIETHYLAMINE
N,N-Diethylethanamine
121-44-8
(Diethylamino)ethane
Ethanamine, N,N-diethyl-
triethyl amine
Triaethylamin
Triethylamin
Trietilamina
N,N,N-Triethylamine
NEt3
trietylamine
tri-ethyl amine
(C2H5)3N
N,N-diethyl-ethanamine
Diethylaminoethane
Triethylamine
Triaethylamin
Trietilamina
CCRIS 4881
HSDB 896
Et3N
TEN
EINECS 204-469-4
triehtylamine
triehylamine
trieihylamine
triethlyamine
triethyamine
TRIETHYLAMINE
Triethylannine
tri-ethylamine
triehyl amine
trietyl amine
tri ethyl amine
triethyl- amine
N, N-diethylethanamine
N,N,N-Triethylamine
TRIETHYLAMINE
EC 204-469-4
N(Et)3
TRIETHYLAMINE
(CH3CH2)3N
N(CH2CH3)3
N(C2H5)3
EN300-35419
Triethylamine
(Diethylamino)ethane
(diethylamino)ethane
ethanamine, N,N-diethyl-
Ethanamine, N,N-diethyl- (9CI)


N,N-DIETHYLETHANOLAMINE
DESCRIPTION:
N,N-DIETHYLETHANOLAMINE (DEEA) is a tertiary alkanolamine multi-component aqueous solvent.
N,N-DIETHYLETHANOLAMINE has a high chemical stability and resistance against degradation.
N,N-DIETHYLETHANOLAMINE is used to prepare quaternary ammonium salts.
These salts are widely used as phase transfer catalysts to promote reactions between immiscible phases.

CAS Number: 100-37-8
EC Number: 202-845-2
Linear Formula:(C2H5)2NCH2CH2OH


SYNONYM(S) OF N,N-DIETHYLETHANOLAMINE:
N,N-Diethylethanolamine, DEAE, DEEA N,N-DIETHYLETHANOLAMINE,N,N-DIETHYLETHANOLAMINE,N,N-DIETHYLETHANOLAMINE,N,N-Diethyl-2-aminoethanol,N,N-Diethylethanolamine,Diethyl(2-hydroxyethyl)amine,(2-Hydroxyethyl)diethylamine,2-Diethylaminoethyl alcohol,2-Hydroxytriethylamine,N,N-DIETHYLETHANOLAMINE,2-HYDROXYTRIETHYLAMINE,BETA-DIETHYLAMINOETHYL ALCOHOL,DIETHYL ETHANOLAMINE,DIETHYLAMINO-2 ETHANOL,N,N-DIETHYLETHANOLAMINE,DIETHYLETHANOLAMINE,DIETHYLETHANOLAMINE (DEEA),N,N-DIETHYLETHANOLAMINE,N,N-DIETHYLETHANOLAMINE,N,N-DIETHYL-2-AMINOETHANOL,N,N-N,N-DIETHYLETHANOLAMINE,N,N-DIETHYLETHANOLAMINE,N,N-DIETHYLETHANOLAMINE,2-(dimethylamino)ethanol hydrochloride,2-(N,N-dimethylamino)ethanol hydrochloride,N,N-DIETHYLETHANOLAMINE,N,N-DIETHYLETHANOLAMINE hydrochloride,N,N-DIETHYLETHANOLAMINE hydrochloride, 14C-labeled,N,N-DIETHYLETHANOLAMINE sulfate (2:1),N,N-DIETHYLETHANOLAMINE tartrate,N,N-DIETHYLETHANOLAMINE, sodium salt,DEAE,deanol hydrochloride,N,N-DIETHYLETHANOLAMINE,diethylethanolamine,ethanol, 2-(dimethylamino)-, hydrochloride (1:1),ethanol, 2-dimethylamino-, hydrochloride,N,N-diethylethanolamine,N,N-DIETHYLETHANOLAMINE,N,N-DIETHYLETHANOLAMINE,N,N-DIETHYLETHANOLAMINE,100-37-8,N,N-Diethylethanolamine,Diethylethanolamine,DEAE,(Diethylamino)ethanol,Ethanol, 2-(diethylamino)-,N,N-Diethyl-2-aminoethanol,(2-Hydroxyethyl)diethylamine,Diethyl(2-hydroxyethyl)amine,2-(Diethylamino)Ethan-1-Ol,Diethylmonoethanolamine,2-Hydroxytriethylamine,Pennad 150,Diaethylaminoaethanol,2-(N,N-Diethylamino)ethanol,N,N-Diethylmonoethanolamine,N,N-Diethyl-2-hydroxyethylamine,beta-N,N-DIETHYLETHANOLAMINE,beta-Hydroxytriethylamine,2-(Diethylamino)ethyl alcohol,Diethylamino ethanol,N-N,N-DIETHYLETHANOLAMINE,2-N-N,N-DIETHYLETHANOLAMINE,diethyl ethanolamine,DEEA,beta-Diethylaminoethyl alcohol,2-diethylamino-ethanol,N-(Diethylamino)ethanol,N,N-Diethyl-N-(beta-hydroxyethyl)amine,NSC 8759,N,N-N,N-DIETHYLETHANOLAMINE,2-(diethylamino)-ethanol,2-N-(Diethylamino)ethanol,.beta.-(Diethylamino)ethanol,ETHANOL,2-DIETHYLAMINO,S6DL4M053U,beta-(Diethylamino)ethyl alcohol,DTXSID5021837,CHEBI:52153,.beta.-(Diethylamino)ethyl alcohol
NSC-8759,N,N-Diethyl-N-(.beta.-hydroxyethyl)amine,DTXCID401837,ethane, 1-diethylamino-2-hydroxy-,CAS-100-37-8,Diaethylaminoaethanol [German],CCRIS 4793,HSDB 329,EINECS 202-845-2,UN2686,UNII-S6DL4M053U,-diethylamino,AI3-16309,2-Diethylamino,Diathylaminoathanol,Diethylamlnoethanol,MFCD00002850,N, N-Diethylethanolamine,beta-(Diethylamino)ethanol,N,N-diethyl ethanol amine,N,N-DIETHYLETHANOLAMINE [UN2686] [Corrosive],.beta.-Hydroxytriethylamine,EC 202-845-2,SCHEMBL3114,N,N-DIETHYLETHANOLAMINE, 9CI,CHEMBL1183,Diaethylaminoaethanol(german),2-(diethylamino)-1-ethanol,MLS002174251,2-(N,N-diethylamino)-ethanol,N,N-DIETHYLETHANOLAMINE, 99%,N,N-DIETHYLETHANOLAMINE [HSDB],N-(beta-hydroxyethyl)diethylamine,NSC8759,HMS3039I08,N,N-DIETHYLETHANOLAMINE, >=99%,N,N-DIETHYLETHANOLAMINE [MART.],WLN: Q2N2 & 2,N,N-DIETHYLETHANOLAMINE [WHO-DD],N-(hydroxyethyl)-N,N-diethyl amine,Tox21_201463,Tox21_300037,BBL012211,STL163552,N,N-DIETHYLETHANOLAMINE [MI],N,N-DIETHYLETHANOLAMINE, >=99.5%,AKOS000119883,UN 2686,NCGC00090925-01,NCGC00090925-02,NCGC00090925-03,NCGC00253920-01,NCGC00259014-01,A 22,BP-20552,SMR001261425,VS-03234,DB-012722,D0465,NS00006343,N,N-DIETHYLETHANOLAMINE [UN2686] [Corrosive],D88192,N,N-DIETHYLETHANOLAMINE, purum, >=99.0% (GC),Q209373,N,N-DIETHYLETHANOLAMINE 100 microg/mL in Acetonitrile,J-520312,Diethyl ethanolamine N,N-DIETHYLETHANOLAMINE 2-Hydroxytriethylamine,InChI=1/C6H15NO/c1-3-7(4-2)5-6-8/h8H,3-6H2,1-2H


N,N-DIETHYLETHANOLAMINE appears as a colorless liquid.
N,N-DIETHYLETHANOLAMINE has Flash point 103-140 °F.
N,N-DIETHYLETHANOLAMINE is Less dense than water.

Vapors of N,N-DIETHYLETHANOLAMINE is heavier than air.
N,N-DIETHYLETHANOLAMINE Produces toxic oxides of nitrogen during combustion.
N,N-DIETHYLETHANOLAMINE Causes burns to the skin, eyes and mucous membranes.

N,N-DIETHYLETHANOLAMINE is a member of the class of ethanolamines that is aminoethanol in which the hydrogens of the amino group are replaced by ethyl groups.
N,N-DIETHYLETHANOLAMINE is a member of ethanolamines, a tertiary amino compound and a primary alcohol.
N,N-DIETHYLETHANOLAMINE is functionally related to an ethanolamine.
N,N-DIETHYLETHANOLAMINE derives from a hydride of a triethylamine.


Diethylethanolamine (DEAE) is the organic compound with the molecular formula (C2H5)2NCH2CH2OH.
A colorless liquid, is used as a precursor in the production of a variety of chemical commodities such as the local anesthetic procaine.


APPLICATIONS OF N,N-DIETHYLETHANOLAMINE:
N,N-DIETHYLETHANOLAMINE (DEEA) can be used as a co-solvent with methyldiethanolamine (MDEA) and sulfolane to investigate the CO2 absorption and desorption behavior in aqueous solutions.
Additionally, DEAE is used to prepare N-substituted glycine derivatives and these compounds are used in the synthesis of peptides and proteins.

N,N-DIETHYLETHANOLAMINE is used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging oxygen.
N,N-DIETHYLETHANOLAMINE reacts with 4-aminobenzoic acid to make procaine.
N,N-DIETHYLETHANOLAMINE is a precursor for DEAE-cellulose resin, which is commonly used in ion exchange chromatography.
N,N-DIETHYLETHANOLAMINE can decrease the surface tension of water when the temperature is increased.[3]
Solutions of N,N-DIETHYLETHANOLAMINE absorb carbon dioxide (CO2).

N,N-DIETHYLETHANOLAMINE can be used as a precursor chemical to procaine.
N,N-DIETHYLETHANOLAMINE is used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging oxygen.
N,N-DIETHYLETHANOLAMINE is used for the synthesis of drugs in the pharmaceutical industry and as a catalyst for the synthesis of polymers in the chemical industry.
N,N-DIETHYLETHANOLAMINE is also used as a pH stabilizer.



USE AND EMISSION SOURCES 1 2 3 4:
N,N-DIETHYLETHANOLAMINE is used as an intermediate in the manufacture of emulsifying agents, specialty soaps and other chemicals for applications in:
Pharmaceutical industry
pesticides
the paper
leather products
plastics
anti-rust products
the paintings
the textile
cosmetics
surface coatings...


PREPARATION OF N,N-DIETHYLETHANOLAMINE:
N,N-DIETHYLETHANOLAMINE is prepared commercially by the reaction of diethylamine and ethylene oxide.[4]
(C2H5)2NH + cyclo(CH2CH2)O → (C2H5)2NCH2CH2OH
N,N-DIETHYLETHANOLAMINE is also possible to prepare it by the reaction of diethylamine and ethylene chlorohydrin.[5


CHEMICAL AND PHYSICAL PROPERTIES OF N,N-DIETHYLETHANOLAMINE:
vapor density
4.04 (vs air)
Quality Level
100
vapor pressure
1 mmHg ( 20 °C)
Assay
≥99.5%
expl. lim.
11.7 %
refractive index
n20/D 1.441 (lit.)
bp
161 °C (lit.)
density
0.884 g/mL at 25 °C (lit.)
SMILES string
CCN(CC)CCO
InChI
1S/C6H15NO/c1-3-7(4-2)5-6-8/h8H,3-6H2,1-2H3
InChI key
BFSVOASYOCHEOV-UHFFFAOYSA-N
Molecular Weight:
117.19
Beilstein:
741863
Chemical formula C6H15NO
Molar mass 117.192 g•mol−1
Appearance Colourless liquid
Odor Ammoniacal
Density 884 mg mL−1
Melting point −70 °C; −94 °F; 203 K[1]
Boiling point 161.1 °C; 321.9 °F; 434.2 K
Solubility in water miscible[1]
log P 0.769
Vapor pressure 100 Pa (at 20 °C)
Refractive index (nD) 1.441–1.442
CAS number 100-37-8
CE index number 603-048-00-6
CE number 202-845-2
Hill formula C₆H₁₅NO
Chemical formula (C₂H₅)₂NCH₂CH₂OH
Molar Mass 117.19 g/mol
Code SH 2922 19 52
Boiling point 163 °C (1013 hPa)
Density 0.88 g/cm3 (20 °C)
Explosion limit 0.7%(V)
Flash point 50 °C
Ignition temperature 270 °C
Fusion point -68 °C
pH value 11.5 (100 g/l, H₂O, 20 °C)
Vapor pressure 1 hPa (20 °C)
Assay (GC, area%) ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C) 0.883 - 0.885
Water (K. F.) ≤ 0.30 %
Identity (IR) passes test
Molecular Weight
117.19 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
XLogP3-AA
0.3
Computed by XLogP3 3.0 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
1
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
2
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
4
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
117.115364102 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
117.115364102 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
23.5Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
8
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
43.8
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
0
Computed by PubChem
Undefined Atom Stereocenter Count
0
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
1
Computed by PubChem
Compound Is Canonicalized
Yes
vapor pressure
1.9 hPa ( 20 °C)
Quality Level
200
Assay
≥99.0% (GC)
form
liquid
autoignition temp.
270 °C
potency
1300 mg/kg LD50, oral (Rat)
1109 mg/kg LD50, skin (Rabbit)

expl. lim.
0.7 % (v/v)
pH
11.5 (20 °C, 100 g/L in H2O)
bp
163 °C/1013 hPa
mp
-68 °C
transition temp
flash point 51 °C
density
0.88 g/cm3 at 20 °C
storage temp.
2-30°C
InChI
1S/C6H15NO/c1-3-7(4-2)5-6-8/h8H,3-6H2,1-2H3
InChI key
BFSVOASYOCHEOV-UHFFFAOYSA-N
Storage Temperature
RT
European Com.#
202-845-2
Hazmat Ship
Check subsku for hazmat
Purity
>99%
Appearance color
Clear, colorless
Appearance form
Liquid
Molecular Formula
C6H15NO
Molecular Weight
117.19
Density
0.884 g/mL at 25°C
Melting point
-70°C
Boiling point
161°C
Solubility (@ RT)
Solubility in water: Soluble
Solubility in other solvents: Soluble in alcohol, ether and benzene
Melting Point -70°C
Density 0.883
pH 11.5
Boiling Point 161°C to 163°C
Flash Point 52°C (125°F)
Odor Amine-like
Linear Formula (CH3CH2)2NCH2CH2OH
Refractive Index 1.4415
Quantity 1000 mL
UN Number UN2686
Beilstein 741863
Sensitivity Air and light sensitive; Hygroscopic
Merck Index 14,3112
Solubility Information It is miscible in water.
Molecular Weight (g/mol) 117.192
Formula Weight 117.19
Percent Purity 99%
Chemical Name or Material N,N-DIETHYLETHANOLAMINE



SAFETY INFORMATION ABOUT N,N-DIETHYLETHANOLAMINE
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.
N,N-DIMEHYL CYCLOHEXYLAMINE-LUPRAGEN N 100
2-(Dimethylamino)Ethanol; N,N-Dimethyl-N-ethanolamine; N,N-Dimethyl-2-aminoethanol; beta-Dimethylaminoethyl alcohol; beta-hydroxyethyldimethylamine; Ddimethylaminoethanol; Deanol; Dimethylethanolamine; Dimethylaminoaethanol (German); N,N-Dimethyl-2-Hydroxyethylamine; N,N-Dimethylaminoethanol; N,N-dimethyl-N-(2-hydroxyethyl)amine; cas no: 108-01-0
N,N-DIMETHYLBENZYLAMINE
N,N-Dimethylbenzylamine is the organic compound with the formula C6H5CH2N(CH3)2.
N,N-Dimethylbenzylamine, also known as N-benzyl-n,n-dimethylamine nitrate or benzyl-dimethyl-amine, is a member of the class of compounds known as phenylmethylamines.


CAS Number: 103-83-3
EC Number: 203-149-1
MDL number: MFCD00008329
Linear Formula: C6H5CH2N(CH3)2
Chemical formula: C9H13N



N,N-DIMETHYLBENZYLAMINE, 103-83-3, Benzyldimethylamine, N-Benzyldimethylamine, N,N-dimethyl-1-phenylmethanamine, Dimethylbenzylamine, BDMA, Benzenemethanamine, N,N-dimethyl-, Benzyl-N,N-dimethylamine, N-(Phenylmethyl)dimethylamine, N,N-Dimethylbenzenemethanamine, Araldite accelerator 062, N,N-Dimethyl-N-benzylamine, N-Benzyl-N,N-dimethylamine, Benzylamine, N,N-dimethyl-, Sumine 2015, N,N'-Dimethylbenzylamine, NSC 5342, Benzyl-dimethyl-amine, TYP7AXQ1YJ, DTXSID8021854, NSC-5342, NCGC00090991-02, 28262-13-7, DTXCID801854, CAS-103-83-3, CCRIS 6693, UNII-TYP7AXQ1YJ, EINECS 203-149-1, UN2619,
Benzenemethanamine, dimethyl-, AI3-26794, Benzenemethamine, N,N-dimethyl-, Dabco BDMA, N,N-dimethyl-1-phenyl-methanamine, benzyldimethyl-amine,
dimethylbenzyl amine, n-dimethylbenzylamine, dimethyl benzyl amine, N,N-Dmethylbenzylamne, N-benzyl dimethylamine, Benzylamine,N-dimethyl-, N,N,-dimethylbenzylamine, N,N-dimethyl benzylamine, N,N-dimethyl-benzylamine, N, N-Dimethylbenzylamine, N,N-dimethyl benzyl amine, Benzenemethanamine,dimethyl-,
EC 203-149-1, dimethyl (phenylmethyl)amine, SCHEMBL15900, MLS002222342, CHEMBL45591, N,N-Dimethyl(phenyl)methanamine, NSC5342, N,N-Dimethylbenzylamine, >=99%, N,N-Dimethyl(phenyl)methanamine #, WLN: 1N1 & 1R, Tox21_113457, Tox21_200719, MFCD00008329, AKOS000120578, UN 2619, NCGC00090991-01,
NCGC00090991-03, NCGC00258273-01, AC-10211, LS-13652, SMR001307284, N,N-Dimethylbenzylamine(Benzyldimethylamine), Benzyldimethylamine [UN2619], D0688, FT-0657620, NS00008694, EN300-16212, N,?N-?Dimethylbenzylamine(Benzyldimethylamine), Q424966, J-001043, J-523270, InChI=1/C9H13N/c1-10(2)8-9-6-4-3-5-7-9/h3-7H,8H2,1-2H, N,N-Dimethylbenzylamine, for protein sequence analysis, >=99.5% (GC), N-Benzyl-N,N-dimethylamine, DBA, Dimethylaminomethyl-benzene, N,N-Dimethylbenzenemethanamine, N,N-Dimethylbenzylamine, DMBA, BDMA, Benzyl-dimethyl-amine, Benzyldimethylamine, Dimethylbenzylamine, DMBA, N,N'-Dimethylbenzylamine, N,N-Dimethyl-1-phenylmethanamine, N,N-Dimethyl-n-benzylamine, N,N-Dimethylbenzenemethanamine, N,N-Dimethylbenzylamine, BDMA, Dabco B-16, BENZYLDIMETHYLAMINE, Dimethylbenzylamine, N-Benzyldimethylamine, aralditeaccelerator062, N,N-Dimethylbenzylamine, N,N-BENZYLDIMETHYLAMINE, Nin-Dimethyl Benzylamine, Benzyl-N,N-dimethylamine, N,N-Dimethyl benzylamine, Araldite accelerator 062, N, N-dimethylbenzylamine, (N,N-Dimethylbenzylamine), Benzylamine, N,N-dimethyl-, N-(Phenylmethyl)dimethylamine, Benzenemethamine, N,N-dimethyl-, N,N-dimethyl-1-phenylmethanamine, Benzenemethanamine,N,N-dimethyl-,
N,N-dimethyl(phenyl)methanaminium, N,N-dimethyl(phenyl)methanaminium chloride, Aralditeaccelerator062, aralditeaccelerator062, Benzenemethamine,N,N-dimethyl-, Benzenemethanamine,N,N-Chemicalbookdimethyl-, Benzylamine,N,N-dimethyl-, Benzyl-N,N-dimethylamine, DabcoB-16, N-(Phenylmethyl)dimethylamine, Benzylamine, N,N-dimethyl-, Benzyldimethylamine, Dimethylbenzylamine, N-Benzyldimethylamine, N,N-Dimethyl-N-benzylamine, N,N-Dimethylbenzylamine, N-Benzyl-N,N-dimethylamine, BDMA, Araldite accelerator 062, Benzyl-N,N-dimethylamine, N,N-Dimethylbenzenemethanamine, N-(Phenylmethyl)dimethylamine, Sumine 2015, UN 2619, Dabco BDMA, Benzenemethamine, N,N-dimethyl-, NSC 5342, N,N-Dimethylbenzylamine, N,N-Dimethyl-1-phenylmethanamine, Benzenemethanamine, N,N-dimethyl-, 103-83-3, Benzenemethanamine, N,N-dimethyl-, . N,N-Dimethyl Benzylamine, [(Dimethylamino)methyl]benzene, Actiron NX 91, Ancamine BDMA, Araldite Accelerator 062, Araldite DY 062, bencildimetilamina, BENZYL DIMETHYLAMINE, BENZYLAMINE, N,N-DIMETHYL-, Benzyldimethylamin, Benzyldimethylamine, Benzyl-N,N-dimethylamine,Dabco BDMA, Desmorapid DB, Dimethylbenzylamine, Kaolizer 20, N-(Phenylmethyl)dimethylamine, N,N-Dimethylbenzenemethanamine, N,N-DIMETHYLBENZYLAMIN, N,N-Dimethyl-N-benzylamine, N-BENZYLDIMETHYLAMINE, N-Benzyl-N,N-dimethylamine, NSC 5342, Sumicure BD, UN 2619, EINECS 203-149-1, Sumine 2015, UNII-TYP7AXQ1YJ, 1338002-71-3, 59125-51-8, N,N-Dimethyl-1-phenylmethanamine, N,N-Dimethylbenzenemethanamine, N,N-Dimethylbenzylamine, N-Benzyldimethylamine, Dimethylbenzylamine, Benzyl-N,N-dimethylamine, N-(Phenylmethyl) dimethylamine, BDMA, Sumine 2015, Benzenemethanamine, Dabco B-16, Araldite accelerator 062, N,N-Dimethyl(phenyl)methanamine, DMBA, N-Benzyldimethylamine, BDMA, DMBA, Dabco B-16, BENZYLDIMETHYLAMINE, Dimethylbenzylamine, N-Benzyldimethylamine, aralditeaccelerator062, N,N-Dimethylbenzylamine, N,N-BENZYLDIMETHYLAMINE, Nin-Dimethyl Benzylamine, Benzyl-N,N-dimethylamine, N,N-Dimethyl benzylamine, Araldite accelerator 062, N, N-dimethylbenzylamine, (N,N-Dimethylbenzylamine), Benzylamine, N,N-dimethyl-, N-(Phenylmethyl)dimethylamine, Benzenemethamine, N,N-dimethyl-, N,N-dimethyl-1-phenylmethanamine, Benzenemethanamine,N,N-dimethyl-, N,N-dimethyl(phenyl)methanaminium, N,N-dimethyl(phenyl)methanaminium chloride, BDMA, N,N-Dimethylbenzenemethanamine, N,N-Dimethylbenzylamine, N-Benzyldimethylamine, Dimethylbenzylamine, Benzyl-N,N-dimethylamine, N-(Phenylmethyl)dimethylamine, BDMA, Sumine 2015, Benzenemethanamine, Dabco B-16, Araldite accelerator 062, N,N-Dimethyl(phenyl)methanamine, BDMA, N,N-DiMethyl-1-phenylMethanaMine, Benzyldimethylamine, N,N-DIETHYLBENZYLAMINE, N,N-Dimethyl-N-benzylamine, BENZYLDIETHYLAMINE, Dabco B-16, sumine2015, Dabco BDMA, Sumine 2015, BDMA, dimethylbenzylamine, N,N-Dimethylbenzylam, N-BENZYLDIETHYLAMINE, Pentamin BDMA etc, Benzyldimethylamine, BENZYLDIETHYLAMINE, Dabco B-16, dimethylaminomethylbenzene, BDMA, EINECS 203-149-1, Benzenemethanamine, N,N-dimethyl-, N,N-dimethyl-N-benzylamine, N,N-dimethylphenylmethanamine, N-benzyl-N,N-dimethylamine, benzyl-N,N-dimethylamine, N-Benzyldimethylamine, N,N-Dimethyl-1-phenylmethanamine, MFCD00026731, N,N-Dimethylbenzylamine, Sumine 2015, AURORA KA-7522, benzyl dimethyl amine, n,n-dimethylbenzylamine, benzyldimethylamine, n-benzyldimethylamine, dimethylbenzylamine, bdma, benzenemethanamine, n,n-dimethyl, benzyl-n,n-dimethylamine, n-phenylmethyl dimethylamine, n,n-dimethylbenzenemethanamine, araldite accelerator 062, Benzylamine, N,N-dimethyl-, Benzyldimethylamine, Dimethylbenzylamine, N-Benzyldimethylamine, N,N-Dimethyl-N-benzylamine, N,N-Dimethylbenzylamine, N-Benzyl-N,N-dimethylamine, BDMA, Araldite accelerator 062, Benzyl-N,N-dimethylamine, N,N-Dimethylbenzenemethanamine, N-(Phenylmethyl)dimethylamine, Sumine 2015, UN 2619, Dabco BDMA, Benzenemethamine, N,N-dimethyl-, NSC 5342, BDMA, N-dimthylbenzylamine, dimethylbenzylamine, benzyldimethylamine, catalystBDMA, rigid foam catalystBDMA,N-Benzyldimethylamine,BDMA,CAS 103 -83-3,



N,N-Dimethylbenzylamine appears as a colorless to light yellow liquid with an aromatic odor.
N,N-Dimethylbenzylamine is a colorless liquid.
N,N-Dimethylbenzylamine appears as a colorless to light yellow liquid with an aromatic odor.


N,N-Dimethylbenzylamine is slightly less dense than water and slightly soluble in water.
N,N-Dimethylbenzylamine is slightly soluble in water.
N,N-Dimethylbenzylamine is slightly less dense than water and slightly soluble in water.


N,N-Dimethylbenzylamine is the organic compound with the formula C6H5CH2N(CH3)2.
N,N-Dimethylbenzylamine is an intermediate for organic synthesis, such as synthesis of quaternary ammonium salt, also used in dehydrogenation catalyst, preservative, acid neutralizer, etc


N,N-Dimethylbenzylamine is the organic compound with the formula C6H5CH2N(CH3)2.
The molecule of N,N-Dimethylbenzylamine consists of a benzyl group, C6H5CH2, attached to a dimethylamino functional group.
N,N-Dimethylbenzylamine, also known as N-benzyl-n,n-dimethylamine nitrate or benzyl-dimethyl-amine, is a member of the class of compounds known as phenylmethylamines.


Phenylmethylamines are compounds containing a phenylmethtylamine moiety, which consists of a phenyl group substituted by an methanamine.
N,N-Dimethylbenzylamine is slightly soluble (in water) and a very strong basic compound (based on its pKa).
N,N-Dimethylbenzylamine displays a broad range of properties, including excellent solvency, a low VOC content, as well as heat and hydrolysis stability


N,N-Dimethylbenzylamine is excellent catalyst with strong adhesive ability in the PU fiel.
N,N-Dimethylbenzylamine is an amine accelerator for polymerization of epoxy resins.
N,N-Dimethylbenzylamine is an organic compound belonging to the aromatic amine family.


N,N-Dimethylbenzylamine is a colorless liquid.
N,N-Dimethylbenzylamine is an amine accelerator for polymerization of epoxy resins.
N,N-Dimethylbenzylamine belongs to a unique class of disubstituted amides with utility in coatings, household,industrial and institutional applications.


Actylis provides N,N-Dimethylbenzylamine in the form of a colourless to slightly yellow liquid with a distinct aromatic odour.
N,N-Dimethylbenzylamine exhibits slight solubility in water and is sensitive to oxygen.
N,N-Dimethylbenzylamine is the organic compound with the formula C6H5CH2N(CH3)2.


N,N-Dimethylbenzylamine can be found in tea, which makes n,n-dimethylbenzylamine a potential biomarker for the consumption of this food product.
N,N-Dimethylbenzylamine belongs to the class of organic compounds known as phenylmethylamines.
Phenylmethylamines are compounds containing a phenylmethtylamine moiety, which consists of a phenyl group substituted by an methanamine.


N,N-Dimethylbenzylamine reacts with Os3(CO)12 to form triosmium clusters.
Anodic oxidation of N,N-Dimethylbenzylamine has been studied in methanol-tetra-n-butylammonium fluoroborate and in methanol-potassium hydroxide.
N,N-Dimethylbenzylamine, also known as N-benzyl-n,n-dimethylamine nitrate or benzyl-dimethyl-amine, is a member of the class of compounds known as phenylmethylamines.


Phenylmethylamines are compounds containing a phenylmethtylamine moiety, which consists of a phenyl group substituted by an methanamine.
N,N-Dimethylbenzylamine is slightly soluble (in water) and a very strong basic compound (based on its pKa).
N,N-Dimethylbenzylamine can be found in tea, which makes n,n-dimethylbenzylamine a potential biomarker for the consumption of this food product.


N,N-Dimethylbenzylamine has been identified in human blood as reported by (PMID: 31557052 ).
N,N-Dimethylbenzylamine is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives.
Technically N,N-Dimethylbenzylamine is part of the human exposome.


The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health.
An individual's exposure begins before birth and includes insults from environmental and occupational sources.
N,N-Dimethylbenzylamine is a colorless, volatile liquid with a low boiling point.



USES and APPLICATIONS of N,N-DIMETHYLBENZYLAMINE:
N,N-Dimethylbenzylamine has been shown to be an effective biocide in the form of its copper complex, which may be used in detergent compositions for the inhibition of microbial growth on surfaces.
N,N-Dimethylbenzylamine was used in the synthesis of bis[(N,N-dimethylamino)benzyl] selenide.


N,N-Dimethylbenzylamine has been used as catalyst during curing reaction of formulations of diglycidyl ether of bisphenol A and tetrahydrophthalic anhydride.
N,N-Dimethylbenzylamineundergoes directed ortho metalation with butyl lithium.


N,N-Dimethylbenzylamine reacts with methyl iodide to get ammonium salt, which is used as phase transfer catalysts.
Further, N,N-Dimethylbenzylamine is used as a catalyst for the formation of polyurethane foams and epoxy resins.
N,N-Dimethylbenzylamine is also used as a standard reagent for determining redox potentials and has been studied extensively in kinetic and analytical chemistry.


The reaction mechanism of N,N-Dimethylbenzylamine has been determined to be similar to that of benzalkonium chloride and other quaternary ammonium salts.
N,N-Dimethylbenzylamine is a direct alternative to DMP-30 with a longer shelf life and better penetration.
N,N-Dimethylbenzylamine is used in the production of polyurethane foams.


N,N-Dimethylbenzylamine is used initiator in the production of epoxy resins.
N,N-Dimethylbenzylamine is also used as a ligand in coordination geometry, transfer reactions, and salt metathesis.
N,N-Dimethylbenzylamine is a moderately active gelling biased tertiary amine catalyst.


As the molecule has tertiary amine functionality, two of the key uses of N,N-Dimethylbenzylamine are as an epoxy-amine cure enhancement catalyst and also as a polyurethane catalyst.
N,N-Dimethylbenzylamine is used an amine accelerator for polymerization of epoxy resins.


N,N-Dimethylbenzylamine is used sensitiser for the photopolymerisation of methacrylates.
N,N-Dimethylbenzylamine is used catalyst for the UV-curing of styrene polyester products.
N,N-Dimethylbenzylamine is used in the manufacture of adhesives; dehydrohalogenating catalyst; corrosion inhibitor; acid neutralizer; potting compounds; cellulose modifier and quaternary ammonium compounds.


N,N-Dimethylbenzylamine catalyst is a versatile catalyst that is utilized in the manufacture of both flexible polyester slabstock and in various types of rigid foams.
N,N-Dimethylbenzylamine is used as a catalyst for the formation of polyurethane foams and epoxy resins.


N,N-Dimethylbenzylamine is used to synthesize quaternary ammonium salts to produce cationic surface active strong fungicides.
N,N-Dimethylbenzylamine is used to promote curing systems such as anhydrides, polyamides, and fatty amines, and accelerates product curing.
N,N-Dimethylbenzylamine can be used alone but is usually used in combination with other amines and/or metal salts in manufacturing processes.


N,N-Dimethylbenzylamine is an amine accelerator for polymerization of epoxy resins.
N,N-Dimethylbenzylamine is recommended in preference to DMP-30 since it is less viscous and has a longer shelf life.
Accelerators should be stored dry in a desiccator, but need not be in a refrigerator.


N,N-Dimethylbenzylamine catalyst is a versatile catalyst that is utilized in the manufacture of both flexible polyester slabstock and in various types of rigid foams.
N,N-Dimethylbenzylamine can be used alone but is usually used in combination with other amines and/or metal salts in manufacturing processes.


N,N-Dimethylbenzylamine is widely used in chemical fields,eg. polyurethane catatlyst, crop pretection, coating, dyestuffs, fungicides, herbicides, insecticides, pharmaceutical agents, textile dyestuffs, textile dyestuffs etc.
When N,N-Dimethylbenzylamine is used as polyurethane catalyst.


N,N-Dimethylbenzylamine has the function of improving the adhesion of the foam surface.
N,N-Dimethylbenzylamine is used for refrigerator, freezer, continuous panel, pipe insulation, croppretection, coating, dyestuffs, fungicides, herbicides, insecticides, pharmaceutical agents, textile dyestuffs, textile dyestuffs etc.


N,N-Dimethylbenzylamine reacts with methyl iodide to get ammonium salt, which is used as phase transfer catalysts.
Further, N,N-Dimethylbenzylamine is used as a catalyst for the formation of polyurethane foams and epoxy resins.
N,N-Dimethylbenzylamine in the polyurethane industry is a catalyst for polyester polyurethane block soft foam, polyurethane rigid foam, polyurethane sheet and adhesive coating.


N,N-Dimethylbenzylamine is also used for flexible slabstock foam applications.
N,N-Dimethylbenzylamine is used in the preparation of bis[(N,N-dimethylamino)benzyl] selenide.
N,N-Dimethylbenzylamine acts as a catalyst in the curing reaction of formulations of diglycidyl ether of bisphenol A and tetrahydrophthalic anhydride.


N,N-Dimethylbenzylamine undergoes directed ortho metalation with butyl lithium.
N,N-Dimethylbenzylamine is also used in the synthesis of quaternary ammonium salts, the production of cationic surface active powerful fungicides, etc.
N,N-Dimethylbenzylamine In epoxy resin is mainly used to promote the curing system of acid anhydride, polyamide, aliphatic amine, etc., and accelerate the curing of products.


N,N-Dimethylbenzylamine is used as a catalyst for soft polyester-based polyurethane systems, semisolid foams, pre-polymerisation agents, to improve the effect of impregnation agents on cellulose fibres.
N,N-Dimethylbenzylamine was used in the synthesis of bis[(N,N-dimethylamino)benzyl] selenide.


N,N-Dimethylbenzylamine is mainly used for rigid foam, can make polyurethane foam have good initial fluidity and uniform cells, and have better adhesion between foam and substrate.
N,N-Dimethylbenzylamine In the field of organic synthesis, it is mainly used as a catalyst, corrosion inhibitor, acid neutralization for the synthesis of dehydrohalogen in organic drugs Accelerators, electron microscope slice embedding accelerators, etc.


N,N-Dimethylbenzylamine is used as a curing accelerator in epoxy resin electronic potting materials, encapsulating materials, epoxy floor coatings, and marine paints.
N,N-Dimethylbenzylamine Specific application examples include: carbon fiber/monomolecular epoxy resin-based composite laminates, electrophoretic coatings for epoxy substrates , Dry-type transformer potting glue.


N,N-Dimethylbenzylamine has been used as catalyst during curing reaction of formulations of diglycidyl ether of bisphenol A and tetrahydrophthalic anhydride.
N,N-Dimethylbenzylamine is intermediate of organic synthesis, such as to synthesize quaternaty ammonium salts and is also used in dehydrogenation catalyst, antiseptic, and acid neutralizer, ETC


N,N-Dimethylbenzylamine finds extensive applications across various industries.
N,N-Dimethylbenzylamine plays a vital role as a curing agent for epoxy resins and is used as a raw material in the manufacturing of adhesives, dyes, and polymers.


N,N-Dimethylbenzylamine serves as an intermediate in the synthesis of numerous organic compounds.
Additionally, N,N-Dimethylbenzylamine is widely utilized as a catalyst in various organic reactions.
Its versatile properties make N,N-Dimethylbenzylamine highly valuable in different industrial processes.


N,N-Dimethylbenzylamine is used for synthesis.
N,N-Dimethylbenzylamine is used in the manufacture of adhesives and other chemicals.
N,N-Dimethylbenzylamine is used in the production of polyurethane foams, Initiator in the production of epoxy resins.


Accelerator for epoxy uses of N,N-Dimethylbenzylamine: resins in laminates for electrical equipment, Sensitizer for the photopolymerization of methacrylates, Catalyst for the UV-curing
of styrene polyester products, Thermal post-cure catalyst for UV-cured epoxy adhesive cement, Synthesis of quats.


N,N-Dimethylbenzylamine is used Textile dyestuffs, Manufacturing of textile dyestuffs, Manufacturing of herbicides, Manufacturing of coating, Manufacturing of pharmaceutical agents, Manufacturing of fungicides, Manufacturing of insecticides / acaricides, Catalyst for chemical synthesis, Manufacturing of textiles dyestuffs, and Crop Protection, and Manufacturing of dyestuffs.


-Principal applications for N,N-Dimethylbenzylamine include:
Catalyst used in the production of polyurethane foams.
Initiator in the production of epoxy resins.
Accelerator for epoxy resins in laminates for electrical equipment.
Sensitizer for the photopolymerisation of methacrylates.



PROPERTIES OF N,N-DIMETHYLBENZYLAMINE:
N,N-Dimethylbenzylamine is a colorless to yellowish flammable liquid.
N,N-Dimethylbenzylamine smells of ammonia.
N,N-Dimethylbenzylamine is soluble in ethanol and ether, but insoluble in water.



CHEMICAL PROPERTIES OF N,N-DIMETHYLBENZYLAMINE:
N,N-Dimethylbenzylamine is a colorless to light yellow flammable liquid with ammonia odor.
N,N-Dimethylbenzylamine is soluble in ethanol, ether, insoluble in water.



PREPARATION OF N,N-DIMETHYLBENZYLAMINE:
25% Aqueous Dimethylamine, 1088 grams
Benzyl Chloride, 126.6 grams
In the apparatus of Example 1, the benzyl chloride was added dropwise over a two-hour period to the amine (molar ratio 1 to 6) at a rate sufficient to maintain the temperature below 40°C.

Stirring was continued at room temperature for an additional hour to insure completion of the reaction denoted by the equation below.
Preparation of N,N-Dimethylbenzylamine
Thereafter the reaction mixture was cooled in a separatory funnel while standing in a refrigerator maintained at 5° C and separated into two layers.

The upper oily layer, weighing 111.5g, was removed and steam distilled until no further oleaginous component was observed in the distillate as it came over.
The crude distillate was found to contain 103.5g of N,N-Dimethylbenzylamine (76.1% of theory), 3.3g of dimethylamine and no quaternary salts.
The dimethylamine was distilled off below 29°C under atmospheric pressure from the N,N-Dimethylbenzylamine (bp 82°C/18mmHg).



ALTERNATIVE PARENTS OF N,N-DIMETHYLBENZYLAMINE:
*Benzylamines
*Aralkylamines
*Trialkylamines
*Organopnictogen compounds
*Hydrocarbon derivatives



SUBSTITUENTS OF N,N-DIMETHYLBENZYLAMINE:
*Phenylmethylamine
*Benzylamine
*Aralkylamine
*Tertiary aliphatic amine
*Tertiary amine
*Organic nitrogen compound
*Organopnictogen compound
*Hydrocarbon derivative
*Organonitrogen compound
*Amine
*Aromatic homomonocyclic compound



SOLUBILITY OF N,N-DIMETHYLBENZYLAMINE:
N,N-Dimethylbenzylamine is slightly miscible with water.



NOTES OF N,N-DIMETHYLBENZYLAMINE:
N,N-Dimethylbenzylamine is air sensitive.
N,N-Dimethylbenzylamine is incompatible with strong acids, strong bases, strong oxidizing agents, strong reducing agents and carbon dioxide.



REACTIVITY PROFILE OF N,N-DIMETHYLBENZYLAMINE:
N,N-Dimethylbenzylamine neutralizes acids on exothermic reactions to form salts plus water.
N,N-Dimethylbenzylamine may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
N,N-Dimethylbenzylamine may attack some plastics



PROPERTIES AND USAGE OF N,N-DIMETHYLBENZYLAMINE:
N,N-Dimethylbenzylamine in the polyurethane industry, it is a catalyst for polyester polyurethane block soft foam, polyurethane rigid foam, polyurethane sheet and adhesive coating.
N,N-Dimethylbenzylamine is mainly used for rigid foam, which can make polyurethane foam have good early fluidity and uniform cells, and good adhesion between body and substrate.

N,N-Dimethylbenzylamine in the field of organic synthesis, it is mainly used as catalysts, corrosion inhibitors, acid neutralizers, and accelerators for embedding electron microscopy slices in organic drugs for the synthesis of dehydrohalogen.
N,N-Dimethylbenzylamine is also used to synthesize quaternary ammonium salts, produce cationic surface active and powerful fungicides, etc.

N,N-Dimethylbenzylamine in terms of epoxy resin, it is mainly used to promote curing systems such as acid anhydrides, polyamides, and fatty amines to accelerate product curing.

N,N-Dimethylbenzylamine is widely used in epoxy resin electronic potting materials, encapsulating materials, epoxy floor coatings, and marine paints.
N,N-Dimethylbenzylamine specificial application examples include: carbon fiber/monomolecular epoxy resin-based composite laminates, electrophoretic coatings for epoxy substrates, and dry-type transformer potting glue.



APPEARANCE PROPERTIES OF N,N-DIMETHYLBENZYLAMINE:
N,N-Dimethylbenzylamine is a colorless to light yellow liquid.
N,N-Dimethylbenzylamine is slightly soluble in cold water, soluble in hot water, and miscible in alcohol and ether.
N,N-Dimethylbenzylamine is a clear, light yellow liquid with an amine-like odour.
N,N-Dimethylbenzylamine is a colorless to slightly yellow transparent liquid, soluble in ethanol, soluble in hot water, slightly soluble in cold water.



SYNTHESIS OF N,N-DIMETHYLBENZYLAMINE:
N,N-Dimethylbenzylamine can be synthesized by the Eschweiler–Clarke reaction of benzylamine



REACTIONS OF N,N-DIMETHYLBENZYLAMINE:
N,N-Dimethylbenzylamine undergoes directed ortho metalation with butyl lithium:

[C6H5CH2N(CH3)2 + BuLi → 2-LiC6H4CH2N(CH3)2
LiC6H4CH2N(CH3)2 + E+ → 2-EC6H4CH2N(CH3)2
Via these reactions, many derivatives are known with the formula 2-X-C6H4CH2N(CH3)2 (E = SR, PR2, etc.).

The amine is basic and undergoes quaternization with alkyl halides (e.g. hexyl bromide) to give quaternary ammonium salts:
[C6H5CH2N(CH3)2 + RX → [C6H5CH2N(CH3)2R]+X−
Such salts are useful phase transfer catalysts.



PHYSICAL and CHEMICAL PROPERTIES of N,N-DIMETHYLBENZYLAMINE:
Molecular Weight: 135.21 g/mol
XLogP3: 2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 2
Exact Mass: 135.104799419 g/mol
Monoisotopic Mass: 135.104799419 g/mol
Topological Polar Surface Area: 3.2Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 82.7
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1

Compound Is Canonicalized: Yes
CAS Min %: 98.5
CAS Max %: 100.0
Melting Point: -75.0°C
Color: Colorless to Yellow
Density: 0.9000g/mL
Boiling Point: 183.0°C to 184.0°C
Flash Point: 54°C
Infrared Spectrum: Authentic
Assay Percent Range: 98.5% min. (GC)
Linear Formula: C6H5CH2N(CH3)2
Refractive Index: 1.5000 to 1.5020
Beilstein: 12, 1019
Specific Gravity: 0.9
Solubility Information:
Solubility in water: 8g/L (20°C).
Other solubilities: soluble in alcohol,acetone,ether and toluene,
reacts with organic and inorganic acids

IUPAC Name: N,N-dimethyl-1-phenylmethanamine
Formula Weight: 135.23
Percent Purity: 99%
Physical Form: Liquid
Chemical Name or Material: N, N-Dimethylbenzylamine, 99%
Water Solubility: 2.83 g/L
logP: 1.84
logP: 1.91
logS: -1.7
pKa (Strongest Basic): 8.99
Physiological Charge: 1
Hydrogen Acceptor Count: 1
Hydrogen Donor Count: 0
Polar Surface Area: 3.24 Ų
Rotatable Bond Count: 2
Refractivity: 44.6 m³·mol⁻¹

Polarizability: 16.24 ų
Number of Rings: 1
Bioavailability: Yes
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: Yes
MDDR-like Rule: No
Chemical Formula: C9H13N
IUPAC name: benzyldimethylamine
InChI Identifier: InChI=1S/C9H13N/c1-10(2)8-9-6-4-3-5-7-9/h3-7H,8H2,1-2H3
InChI Key: XXBDWLFCJWSEKW-UHFFFAOYSA-N
Isomeric SMILES: CN(C)CC1=CC=CC=C1
Average Molecular Weight: 135.2062
Monoisotopic Molecular Weight: 135.104799421



FIRST AID MEASURES of N,N-DIMETHYLBENZYLAMINE:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of N,N-DIMETHYLBENZYLAMINE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of N,N-DIMETHYLBENZYLAMINE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of N,N-DIMETHYLBENZYLAMINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of N,N-DIMETHYLBENZYLAMINE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of N,N-DIMETHYLBENZYLAMINE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


N,N-DIMETHYLCYCLOHEXYLAMINE (DMCHA)
N,N-Dimethylcyclohexylamine (DMCHA) is a chemical compound with the molecular formula C8H17N.
N,N-Dimethylcyclohexylamine (DMCHA) is an organic amine derivative characterized by a cyclohexylamine core structure with two methyl groups (CH3) attached to the nitrogen atom.
N,N-Dimethylcyclohexylamine (DMCHA), colorless or pale yellow transparent liquid, melting point 60 ℃,boiling point 160 ℃.

CAS Number: 98-94-2
Molecular Formula: C8H17N
Molecular Weight: 127.23
EINECS Number: 202-715-5

98-94-2, N-Cyclohexyldimethylamine, Cyclohexylamine, N,N-dimethyl- (6CI,7CI,8CI); N,N-Dimethylcyclohexanamine; (Dimethylamino)cyclohexane; Cyclohexyldimethylamine; DMCHA; DY 8; Dabco PC 8; Desmorapid 726B; Jeffcat DMCHA; KL 10; Kao 10; Kaolizer 10; Lupragen N 100; N,N-Dimethylaminocyclohexane; N,N-Dimethylcyclohexylamine; N-Cyclohexyl-N,N-dimethylamine; N-Cyclohexyldimethylamine; NSC 163904; Niax C 8; PC 8; PC 8 catalyst; PC CAT DMCHA; PC CAT NP 33R; Polycat 8; SFC; Tegoamin DMCHA; Toyocat DMCH; Wandamin DMCA; Wondamine DMCA; Y 12; Y 12 (catalyst)

N,N-Dimethylcyclohexylamine (DMCHA) neutralizes acids in exothermic reactions to form salts plus water.
May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

N,N-Dimethylcyclohexylamine (DMCHA) is widely used as pharmaceutical intermediates and catalyst.
N,N-Dimethylcyclohexylamine (DMCHA) is a colorless liquid with a musky ammonia odor.
N,N-Dimethylcyclohexylamine (DMCHA) is a colorless liquid with a musky ammonia odor.

N,N-Dimethylcyclohexylamine (DMCHA) is a tertiary amine consisting of cyclohexane having a dimethylamino substituent.
N,N-Dimethylcyclohexylamine (DMCHA) catalyst is a strongly basic, general purpose catalyst recommended for a broad range of rigid and semirigid urethane foams, including spray, slabstock, laminations and refrigeration insulation panels.
N,N-Dimethylcyclohexylamine (DMCHA) catalyst, which is readily soluble in most polyols and organic solvents but essentially insoluble in water, shows excellent stability in B-compounds and can be batched with polyols or metered separately.

N,N-Dimethylcyclohexylamine (DMCHA) catalyst is a strongly basic, colorless liquid tertiary amine.
N,N-Dimethylcyclohexylamine (DMCHA) has a strong ammonia smell, placed for a long time the color will gradually become darker, but will not affect its chemical activity.
N,N-Dimethylcyclohexylamine (DMCHA) is soluble in most polyols and organic solvents, but insoluble in water.

N,N-Dimethylcyclohexylamine (DMCHA) catalyst is a strongly basic, colorless liquid tertiary amine.
N,N-Dimethylcyclohexylamine (DMCHA) has a strong ammonia smell, placed for a long time the color will gradually become darker, but will not affect its chemical activity.
N,N-Dimethylcyclohexylamine (DMCHA) is soluble in most polyols and organic solvents, but insoluble in water.

N,N-Dimethylcyclohexylamine (DMCHA) is a moderately active amine catalyst with low viscosity and can be used in a wide range of hard foams.
One of the main applications is insulation foam, coating, plate, laminate, field pouring and refrigeration formulations.
N,N-Dimethylcyclohexylamine (DMCHA) is a versatile chemical compound used in various applications such as pharmaceuticals, agrochemicals, and polymer production.

N,N-Dimethylcyclohexylamine (DMCHA) is commonly used as a curing agent in epoxy resins and polyurethane coatings.
N,N-Dimethylcyclohexylamine (DMCHA) comes in a 25mL bottle and should be stored in a cool, dry place away from sources of heat or ignition.
N,N-Dimethylcyclohexylamine (DMCHA) can cause skin irritation, so gloves and protective clothing should be worn when handling it.

In case of contact with eyes or skin, rinse thoroughly with water and seek medical attention if necessary.
Performance data shows that N,N-Dimethylcyclohexylamine (DMCHA) meets high purity standards for use in industrial processes.
N,N-Dimethylcyclohexylamine (DMCHA) is a low viscosity amil3e catalyst for rigid foams.

N,N-Dimethylcyclohexylamine (DMCHA) Appearanee: colorless to light yellow transparent liquid Assay:99%(GC) Molsture≤0.5% Color≤50# ( APHA)
N,N-Dimethylcyclohexylamine (DMCHA) catalyst is recommended for evaluation in a broad range of rigid foams.
A major application is insulation foams, including spray, slabstock, board laminate and refrigeration formulations.

N,N-Dimethylcyclohexylamine (DMCHA) catalyst is also used in rigid foam furniture frame and decorative parts manufacturing.
N,N-Dimethylcyclohexylamine (DMCHA) can be used alone without any tin catalyst, or used together with other catalysts depending on rocess and specific requirements.
N,N-Dimethylcyclohexylamine (DMCHA) is a low-viscosity medium-active amine catalyst, used for refrigerator hard foam, board, spraying, and on-site infusion of polyurethane hard foam.

The catalyst has a catalytic effect on both gel and foaming, and provides a more balanced catalytic performance for the foaming reaction and gelation reaction of rigid foam.
N,N-Dimethylcyclohexylamine (DMCHA) has stronger catalysis for the reaction of water and isocyanate (foaming reaction), and at the same time The reaction of polyol and isocyanate also has moderate catalysis, it is a strong initial catalyst for foam reaction.
N,N-Dimethylcyclohexylamine (DMCHA) is a strongly basic, clear, colorless-to-straw liquid tertiary amine.

The material has a characteristic amine odor.
N,N-Dimethylcyclohexylamine (DMCHA) will darken on standing, with no effect on reactivity.
N,N-Dimethylcyclohexylamine (DMCHA) is readily soluble in most polyols and organic solvents but is essentially insoluble in water.

N,N-Dimethylcyclohexylamine (DMCHA) is a tertiary amine used primarily to promote the urethane (polyol-isocyanate) reaction in a wide range of rigid foam applications.
N,N-Dimethylcyclohexylamine (DMCHA) is colourless liquid, with characteristic odour and good miscibility with most organic solvents.
N,N-Dimethylcyclohexylamine (DMCHA) has vigorous reaction with organic acides.

N,N-Dimethylcyclohexylamine (DMCHA) consists of a cyclohexane ring with an amino group (NH2) and two methyl groups (CH3) attached to the nitrogen atom.
Its chemical structure is similar to other cyclohexylamine derivatives but with two methyl substituents.
N,N-Dimethylcyclohexylamine (DMCHA) is a colorless to pale yellow liquid at room temperature.

N,N-Dimethylcyclohexylamine (DMCHA) has a characteristic amine odor and is miscible with organic solvents such as alcohols, ethers, and hydrocarbons.
N,N-Dimethylcyclohexylamine (DMCHA)'s physical properties make it suitable for use as a solvent or additive in various chemical processes.
N,N-Dimethylcyclohexylamine (DMCHA) finds applications in several industrial processes and chemical reactions.

N,N-Dimethylcyclohexylamine (DMCHA) is commonly used as a catalyst or catalyst precursor in organic synthesis, particularly in the production of polyurethane foams, resins, and coatings.
N,N-Dimethylcyclohexylamine (DMCHA) can also function as a corrosion inhibitor, pH regulator, or stabilizer in certain formulations.
One of the primary uses of N,N-Dimethylcyclohexylamine (DMCHA) is in the production of polyurethane materials.

N,N-Dimethylcyclohexylamine (DMCHA) serves as a tertiary amine catalyst in the polyurethane foam manufacturing process, where it promotes the reaction between polyols and isocyanates to form polyurethane foam products.
N,N-Dimethylcyclohexylamine (DMCHA) contributes to the foaming and curing of polyurethane systems, leading to the formation of rigid or flexible foam structures with desired properties.
N,N-Dimethylcyclohexylamine (DMCHA) may be employed as a corrosion inhibitor in various applications, such as metalworking fluids, cooling water systems, or oil and gas production.

As a corrosion inhibitor, N,N-Dimethylcyclohexylamine (DMCHA) helps protect metal surfaces from corrosion by forming a protective film or inhibiting corrosive reactions between metals and environmental factors.
N,N-Dimethylcyclohexylamine (DMCHA) is used in polyurethane plastics and textiles and as a chemical intermediate.
Colorless liquid with a musky ammonia odor.

N,N-Dimethylcyclohexylamine (DMCHA) neutralizes acids in exothermic reactions to form salts plus water.
May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

This amine is used as a catalyst in the production of polyurethane foams.
N,N-Dimethylcyclohexylamine (DMCHA) is also used as an intermediate for rubber accelerators and dyes and in the treatment of textiles.
N,N-Dimethylcyclohexylamine (DMCHA) is a low-viscosity, moderately active amine catalyst that can be used in a wide range of rigid foams.

One of the main applications is the formulation of insulating foams, spray coatings, plates, plywood, on-site pouring and refrigeration.
N,N-Dimethylcyclohexylamine (DMCHA) is also suitable for the manufacture of rigid foam furniture frames and decorative parts.
N,N-Dimethylcyclohexylamine (DMCHA) is especially suitable for the preparation of two-component systems.

N,N-Dimethylcyclohexylamine (DMCHA) can be dissolved in many rigid foam polyols and additives.
In the combination, the performance is stable, no need to add organic tin, moderate activity, large adjustability, and long-term Store.
Adding appropriate amount of LCA-1 and LCA-3 to the large-capacity refrigerator combination material can improve the foam flow performance.

Generally, the amount of hard foam is about 3% of polyether, and auxiliary catalyst can also be added according to product requirements.
N,N-Dimethylcyclohexylamine (DMCHA) has ammonia and bitter taste, has a stimulating effect on the skin, and has certain toxicity.
N,N-Dimethylcyclohexylamine (DMCHA) is necessary to wear protective equipment during production.

N,N-Dimethylcyclohexylamine (DMCHA) is a low-viscosity, moderately active amine catalyst used for refrigerator hard foams, plates, spray coating, and in-situ polyurethane hard foam infusion.
N,N-Dimethylcyclohexylamine (DMCHA) catalyst has a catalyst effect on both gel and foam.
N,N-Dimethylcyclohexylamine (DMCHA) provides a more balanced catalytic performance for the foaming reaction and gel reaction of hard foam.

N,N-Dimethylcyclohexylamine (DMCHA) has moderate catalytic activity for the reaction of water and isocyanate.
N,N-Dimethylcyclohexylamine (DMCHA) is a strong initial catalyst for foam reaction.
N,N-Dimethylcyclohexylamine (DMCHA) can be used as a separate catalyst, but it is generally shared with other catalysts.

According to the difference in reaction speed and foam properties, the amount of N,N-Dimethylcyclohexylamine (DMCHA) per 100 parts of polyether polyol is between 0.5-3.5 parts.
In addition to being used for hard foams,N,N-Dimethylcyclohexylamine (DMCHA) can be used as an auxiliary catalyst for molding soft foams and semi-rigid foams.
N,N-Dimethylcyclohexylamine (DMCHA) can function as a solvent or co-solvent in chemical processes where solubility and compatibility with other components are required.

N,N-Dimethylcyclohexylamine (DMCHA) may be used in formulations for paints, coatings, adhesives, and cleaning agents, where its solvency properties contribute to product performance and stability.
N,N-Dimethylcyclohexylamine (DMCHA) is generally considered to have low acute toxicity, it is important to handle it with care and follow appropriate safety precautions.

Direct contact with N,N-Dimethylcyclohexylamine (DMCHA) may cause skin and eye irritation, and inhalation of its vapors may cause respiratory irritation.
Proper ventilation, personal protective equipment, and safe handling practices should be employed when working with DMCHA to minimize exposure risks.

Melting point: -60 °C
Boiling point: 158-159 °C (lit.)
Density: 0.849 g/mL at 25 °C (lit.)
vapor pressure: 3.6 mm Hg ( 20 °C)
refractive index: n20/D 1.454(lit.)
Flash point: 108 °F
storage temp.: Store below +30°C.
solubility: 10 g/L (20°C)
form: Liquid
pka: pK1:10.72(+1) (25°C)
color: Clear
PH: 12 (5g/l, H2O, 20℃)
explosive limit 3.6-19%(V)
Viscosity: 1.49mm2/s
Water Solubility: 10 g/L (20 ºC)
FreezingPoint: <-77℃
Sensitive: Air Sensitive
BRN: 1919922
Dielectric constant: 2.8599999999999999
InChIKey: SVYKKECYCPFKGB-UHFFFAOYSA-N
LogP: 2.31 at 25℃

N,N-Dimethylcyclohexylamine (DMCHA) neutralizes acids in exothermic reactions to form salts plus water.
May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

N,N-Dimethylcyclohexylamine (DMCHA) is low viscosity Amine catalyst, Acts as a widely used catalyst.
Applications of MOFAN 8 include all types of rigid packaging foam.
Specially used in the two components system, soluble with many kinds of rigid polyol and additive.

N,N-Dimethylcyclohexylamine (DMCHA) is stable, compatible in the blend polyols.
Specially used in the two components system, soluble with many kinds of rigid polyol and additive.
N,N-Dimethylcyclohexylamine (DMCHA) is stable, compatible in the blend polyols.

N,N-Dimethylcyclohexylamine (DMCHA) is a tertiary amine used primarily to promote the urethane (polyol-isocyanate) reaction in a wide range of rigid foam applications.
N,N-Dimethylcyclohexylamine (DMCHA) is recommended for evaluation in a broad range of rigid foams.
A major application is insulation foams, including spray, slabstock, board laminate and refrigeration formulations.

N,N-Dimethylcyclohexylamine (DMCHA) is also used in rigid foam furniture frame and decorative parts manufacturing.
N,N-Dimethylcyclohexylamine (DMCHA) can be batched with the polyol or metered as a separate stream.
N,N-Dimethylcyclohexylamine (DMCHA) can be used in a wide range of rigid foams.

One of the main applications is insulation foam, including formulations for sprays, plates, laminates and cold storage.
N,N-Dimethylcyclohexylamine (DMCHA) is also suitable for the manufacture of rigid foam furniture frames and decorative parts.
The catalyst used in rigid foam products can be used as the main catalyst alone without adding organotin, and it can also be supplemented by JD series catalysts according to the process and product requirements.

N,N-Dimethylcyclohexylamine (DMCHA) is also used as an intermediate for rubber accelerators and synthetic fibers.
N,N-Dimethylcyclohexylamine (DMCHA) is mainly used as a catalyst for rigid polyurethane foam.
N,N-Dimethylcyclohexylamine (DMCHA) can also be used as a stabilizer for fuel oil, a stabilizing additive for 150-480°C petroleum fractions, a rubber accelerator and an intermediate for synthetic fibers.

As a polyurethane catalyst, N,N-Dimethylcyclohexylamine (DMCHA) can provide a relatively balanced catalytic effect on the foaming reaction and gelation reaction of polyurethane rigid foam.
N,N-Dimethylcyclohexylamine (DMCHA) is a strongly basic, clear, colorless-to-straw liquid tertiary amine.
The material has a characteristic amine odor.

N,N-Dimethylcyclohexylamine (DMCHA) will darken on standing, with no effect on reactivity.
N,N-Dimethylcyclohexylamine (DMCHA) is readily soluble in most polyols and organic solvents but is essentially insoluble in water.
N,N-Dimethylcyclohexylamine (DMCHA) is a tertiary amine used primarily to promote the urethane (polyol-isocyanate) reaction in a wide range of rigid foam applications.

N,N-Dimethylcyclohexylamine (DMCHA) is a kind of tertiary amine catalyst with strong alkalinity and moderate activity, widely used in rigid polyurethane foam in the world.
N,N-Dimethylcyclohexylamine (DMCHA) is especially suitable to make two components system and no need to add organotin in system polyol.
N,N-Dimethylcyclohexylamine (DMCHA) has moderate activity, strong stability, good adjustability and can be stored for a long time.

When used in system polyol for the high capacity refrigerator, it can improve the foam fluidity.
Stored in cool and well-ventilated storeroom.
Temperature of storeroom should be no high than 30℃.

Should be separately stored from oxidizing agent and acids, avoid mixing storage.
Use explosion proof lighting and ventilation facilities.
Forbidden to use mechanical equipment and tools easy to cause sparkle.

There should be emergency treatment equipment for leakage and proper material for collecting in the storage area.
N,N-Dimethylcyclohexylamine (DMCHA) is mainly used as catalyst in rigid polyurethane foam plastics for refrigerator, panel, spray and casting.
N,N-Dimethylcyclohexylamine (DMCHA) has balanced catalytic performance in foam reaction and gel reaction of rigid foam.

N,N-Dimethylcyclohexylamine (DMCHA) has stronger catalytic property in the reaction of water and isocyanate, also has moderate catalytic in the reaction of polyol and isocyanate.
N,N-Dimethylcyclohexylamine (DMCHA)'s a strong initial catalyst in the foam reaction.
In addition to polyurethane rigid foam, N,N-Dimethylcyclohexylamine (DMCHA) can also be used as aided catalyst in polyurethane molding soft foam, semi-rigid foam.

N,N-Dimethylcyclohexylamine (DMCHA) serves as a catalyst or catalyst precursor in a wide range of chemical reactions beyond polyurethane production.
N,N-Dimethylcyclohexylamine (DMCHA) can catalyze various organic transformations, such as esterifications, amidations, and alkylation reactions.
N,N-Dimethylcyclohexylamine (DMCHA)'s catalytic activity stems from its basicity and nucleophilicity, which facilitate the activation of substrates and the formation of desired products.

In addition to polyurethane foam production, N,N-Dimethylcyclohexylamine (DMCHA) is used in other polyurethane applications, including sealants, adhesives, elastomers, and coatings.
Its role as a catalyst contributes to the formation of cross-linked polyurethane networks with specific properties, such as flexibility, durability, and thermal insulation.
N,N-Dimethylcyclohexylamine (DMCHA) can function as a hydrogen sulfide (H2S) scavenger in oil and gas production and refining operations.

N,N-Dimethylcyclohexylamine (DMCHA) reacts with hydrogen sulfide gas to form non-toxic and water-soluble products, thereby reducing the concentration of H2S in gas streams and preventing corrosion in pipelines and equipment.
N,N-Dimethylcyclohexylamine (DMCHA) is sometimes employed as an alkaline accelerator in epoxy resin systems.
N,N-Dimethylcyclohexylamine (DMCHA) enhances the curing kinetics of epoxy resins when used in combination with other curing agents or accelerators.

N,N-Dimethylcyclohexylamine (DMCHA) accelerates the epoxy curing process at ambient or elevated temperatures, leading to faster curing times and improved mechanical properties of epoxy coatings and composites.
N,N-Dimethylcyclohexylamine (DMCHA) may be utilized in water treatment applications, particularly as a pH regulator or alkalinity adjuster.
N,N-Dimethylcyclohexylamine (DMCHA) can be added to water treatment formulations to control pH levels and alkalinity in industrial processes, wastewater treatment plants, and cooling water systems.

N,N-Dimethylcyclohexylamine (DMCHA)'s buffering capacity helps maintain stable pH conditions and prevent corrosion or scaling in water systems.
N,N-Dimethylcyclohexylamine (DMCHA) serves as a chemical intermediate in the synthesis of various organic compounds and specialty chemicals.
N,N-Dimethylcyclohexylamine (DMCHA) undergoes reactions with other functional groups, such as acids, alcohols, and isocyanates, to produce derivatives with specific properties or functionalities.

N,N-Dimethylcyclohexylamine (DMCHA)'s versatility as a building block enables the synthesis of diverse chemical products in the pharmaceutical, agrochemical, and fine chemical industries.
As with any chemical substance, N,N-Dimethylcyclohexylamine (DMCHA) is subject to regulatory requirements and guidelines governing its production, handling, transportation, and use. Regulatory agencies, such as the Environmental Protection Agency (EPA) and the Occupational Safety and Health Administration (OSHA), establish standards and regulations to ensure the safe management of DMCHA and protect human health and the environment.

Uses:
N,N-Dimethylcyclohexylamine (DMCHA) is used in polyurethane plastics and textiles and as a chemical intermediate.
The curing temperature of baking finishes comprising polyurethane-forming substances can be reduced by 50 – 80 ℃ by adding weakly acidic derivatives of N,N-Dimethylcyclohexylamine (DMCHA).
Like pyridine, N,N-Dimethylcyclohexylamine (DMCHA) catalyzes certain reactions and is slightly more efficient than pyridine in the preparation of acid chlorides with thionyl chloride.

N,N-Dimethylcyclohexylamine (DMCHA) can be used as corrosion inhibitor and as an antioxidant in fuel oils.
N,N-Dimethylcyclohexylamine (DMCHA) is incorporated into adhesive formulations, particularly in industries such as construction, automotive, and aerospace.
N,N-Dimethylcyclohexylamine (DMCHA) serves as a curing agent or accelerator in epoxy adhesives, helping to enhance bonding strength, durability, and chemical resistance.

N,N-Dimethylcyclohexylamine (DMCHA)-based adhesives are used in bonding applications requiring high performance and reliability.
N,N-Dimethylcyclohexylamine (DMCHA) is utilized in the formulation of sealants used in construction, automotive, and marine applications.
N,N-Dimethylcyclohexylamine (DMCHA) functions as a cross-linking agent or accelerator in polyurethane-based sealants, contributing to the formation of durable and weather-resistant seals.

N,N-Dimethylcyclohexylamine (DMCHA)-based sealants are employed for sealing joints, seams, and gaps in buildings, vehicles, and marine structures.
N,N-Dimethylcyclohexylamine (DMCHA) may be used as a fuel additive to improve the combustion characteristics and stability of fuels, such as gasoline and diesel.
N,N-Dimethylcyclohexylamine (DMCHA) can enhance fuel efficiency, reduce emissions, and inhibit the formation of deposits in engine systems.

N,N-Dimethylcyclohexylamine (DMCHA)-based fuel additives are employed in automotive, marine, and aviation applications to optimize engine performance and reduce environmental impact.
In polymer formulations, N,N-Dimethylcyclohexylamine (DMCHA) can function as a plasticizer to improve the flexibility, elongation, and impact resistance of plastic materials.
N,N-Dimethylcyclohexylamine (DMCHA) helps modify the mechanical properties of polymers, making them more suitable for applications requiring flexibility or toughness.

N,N-Dimethylcyclohexylamine (DMCHA)-based plasticizers are used in the production of PVC, polyurethane, and other plastic products.
N,N-Dimethylcyclohexylamine (DMCHA) is utilized as a resin modifier or additive in the formulation of coatings, paints, and polymer resins.
N,N-Dimethylcyclohexylamine (DMCHA) can enhance the flow properties, adhesion, and film formation characteristics of resin systems.

N,N-Dimethylcyclohexylamine (DMCHA)-based modifiers improve the performance and appearance of coatings and paints, leading to smoother finishes, better adhesion, and increased durability.
N,N-Dimethylcyclohexylamine (DMCHA) serves as a precursor in the synthesis of surfactants and emulsifiers used in detergents, personal care products, and industrial cleaners.
N,N-Dimethylcyclohexylamine (DMCHA) undergoes chemical reactions to produce quaternary ammonium compounds or amphiphilic molecules with surface-active properties.

N,N-Dimethylcyclohexylamine (DMCHA)-derived surfactants aid in the dispersion, wetting, and emulsification of substances in aqueous and non-aqueous systems.
N,N-Dimethylcyclohexylamine (DMCHA) is employed in textile finishing and treatment processes to impart water repellency, antistatic properties, or flame retardancy to fabrics.
N,N-Dimethylcyclohexylamine (DMCHA) can be incorporated into fabric coatings, finishes, or treatments to enhance performance and functionality.

N,N-Dimethylcyclohexylamine (DMCHA)-based treatments are applied to textiles used in apparel, home furnishings, and technical textiles.
In the oil and gas industry, N,N-Dimethylcyclohexylamine (DMCHA) is utilized in the formulation of drilling fluids, completion fluids, and production chemicals.
N,N-Dimethylcyclohexylamine (DMCHA) functions as a pH buffer, corrosion inhibitor, or scavenger in oilfield operations to maintain well integrity, control fluid properties, and mitigate downhole challenges.

N,N-Dimethylcyclohexylamine (DMCHA)-based chemicals contribute to the efficiency and reliability of oil and gas exploration and production processes.
Release to the environment of N,N-Dimethylcyclohexylamine (DMCHA) can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release.
Other release to the environment of N,N-Dimethylcyclohexylamine (DMCHA) is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

N,N-Dimethylcyclohexylamine (DMCHA) can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones).
N,N-Dimethylcyclohexylamine (DMCHA) is used in the following products: polymers and adhesives and sealants.
N,N-Dimethylcyclohexylamine (DMCHA) is used in the following areas: formulation of mixtures and/or re-packaging, mining and building & construction work.

N,N-Dimethylcyclohexylamine (DMCHA) is used for the manufacture of: plastic products, machinery and vehicles and .
Release to the environment of N,N-Dimethylcyclohexylamine (DMCHA) can occur from industrial use: formulation in materials and in the production of articles.
Other release to the environment of N,N-Dimethylcyclohexylamine (DMCHA) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).

N,N-Dimethylcyclohexylamine (DMCHA) is used in the following products: polymers.
Release to the environment of N,N-Dimethylcyclohexylamine (DMCHA) can occur from industrial use: formulation in materials, in the production of articles and formulation of mixtures.
Other release to the environment of N,N-Dimethylcyclohexylamine (DMCHA) is likely to occur from: indoor use, outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

N,N-Dimethylcyclohexylamine (DMCHA) is used in the following products: polymers and adhesives and sealants.
N,N-Dimethylcyclohexylamine (DMCHA) is used in the following areas: mining and building & construction work.
N,N-Dimethylcyclohexylamine (DMCHA) is used for the manufacture of: plastic products, machinery and vehicles and furniture.

Release to the environment of N,N-Dimethylcyclohexylamine (DMCHA) can occur from industrial use: in the production of articles, formulation in materials and in processing aids at industrial sites.
Other release to the environment of N,N-Dimethylcyclohexylamine (DMCHA) is likely to occur from: outdoor use, indoor use, outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).
N,N-Dimethylcyclohexylamine (DMCHA) can be used in a wide range of rigid foams.

One of the main applications is insulation foam, including formulations for sprays, plates, laminates and cold storage.
N,N-Dimethylcyclohexylamine (DMCHA) is also suitable for the manufacture of rigid foam furniture frames and decorative parts.
The catalyst used in rigid foam products can be used as the main catalyst alone without adding organotin, and it can also be supplemented by JD series catalysts according to the process and product requirements.

N,N-Dimethylcyclohexylamine (DMCHA) is also used as an intermediate for rubber accelerators and synthetic fibers.
N,N-Dimethylcyclohexylamine (DMCHA) is mainly used as rubber accelerator and the intermediate of synthetic fiber.
N,N-Dimethylcyclohexylamine (DMCHA) can also be used as Pharmaceutical intermediates.

N,N-Dimethylcyclohexylamine (DMCHA) is primarily used as a catalyst in the production of polyurethane foams, elastomers, coatings, and adhesives.
N,N-Dimethylcyclohexylamine (DMCHA) facilitates the reaction between polyols and isocyanates, promoting the formation of polyurethane polymers.
N,N-Dimethylcyclohexylamine (DMCHA) helps control the foam's expansion rate, density, and mechanical properties, making it valuable in the manufacture of flexible and rigid polyurethane products.

N,N-Dimethylcyclohexylamine (DMCHA) is utilized as a corrosion inhibitor in industrial processes involving metals susceptible to corrosion.
N,N-Dimethylcyclohexylamine (DMCHA) forms a protective layer on metal surfaces, preventing corrosion caused by exposure to corrosive environments, such as water, acids, or salts.
N,N-Dimethylcyclohexylamine (DMCHA) is commonly employed in cooling water systems, metalworking fluids, and oilfield operations to protect equipment and infrastructure from degradation.

N,N-Dimethylcyclohexylamine (DMCHA) serves as a catalyst or co-catalyst in various chemical reactions, including esterifications, amidations, and alkylations.
Its basicity and nucleophilicity enhance reaction rates and selectivity, making it valuable in organic synthesis, polymerization, and specialty chemical manufacturing.
N,N-Dimethylcyclohexylamine (DMCHA)'s catalytic properties contribute to the synthesis of a wide range of organic compounds and intermediates.

In epoxy resin systems, N,N-Dimethylcyclohexylamine (DMCHA) functions as an alkaline accelerator, accelerating the curing process of epoxy resins.
N,N-Dimethylcyclohexylamine (DMCHA) enhances the cross-linking reactions between epoxy groups and curing agents, leading to faster curing times and improved mechanical properties of epoxy coatings, adhesives, and composites.
N,N-Dimethylcyclohexylamine (DMCHA) is particularly useful in ambient-temperature curing applications.

Hydrogen Sulfide Scavenging: DMCHA is employed as a hydrogen sulfide (H2S) scavenger in oil and gas production, refining, and transportation.
N,N-Dimethylcyclohexylamine (DMCHA) reacts with hydrogen sulfide gas to form non-toxic and water-soluble products, preventing H2S-related corrosion and souring issues in pipelines, storage tanks, and processing facilities.
N,N-Dimethylcyclohexylamine (DMCHA) helps maintain safe operating conditions and extends the lifespan of equipment in the oil and gas industry.

N,N-Dimethylcyclohexylamine (DMCHA) is used in water treatment applications as a pH regulator and alkalinity adjuster.
N,N-Dimethylcyclohexylamine (DMCHA) helps control pH levels and alkalinity in industrial water systems, wastewater treatment plants, and boiler feedwater to prevent corrosion, scaling, and microbial growth.
N,N-Dimethylcyclohexylamine (DMCHA)'s buffering capacity stabilizes water chemistry and ensures optimal operating conditions in water treatment processes.

N,N-Dimethylcyclohexylamine (DMCHA) serves as a versatile chemical intermediate in the synthesis of various organic compounds and specialty chemicals.
N,N-Dimethylcyclohexylamine (DMCHA) undergoes reactions with acids, alcohols, isocyanates, and other functional groups to produce derivatives used in pharmaceuticals, agrochemicals, surfactants, and coatings.
N,N-Dimethylcyclohexylamine (DMCHA)'s role as a building block enables the synthesis of custom-designed molecules with specific properties and functionalities.

Health Hazard:
Industrial hygiene studies in polyurethane manufacturing plants have identified levels of 0.007-0.81 p.p.m.
N,N-Dimethylcyclohexylamine (DMCHA) in air; however, these levels were not regarded as hazardous.
There are no current exposure standards for N,N-Dimethylcyclohexylamine (DMCHA) and no documentation of human toxicological effects.

Safety Profile:
Poison by ingestion.
Moderately toxic by inhalation.
Whenheated to decomposition it emits toxic fumes of NOx.

Direct contact with N,N-Dimethylcyclohexylamine (DMCHA) may cause irritation to the skin and eyes.
Symptoms of skin irritation include redness, itching, and dermatitis, while eye irritation may result in redness, tearing, and discomfort.
Prolonged or repeated exposure to N,N-Dimethylcyclohexylamine (DMCHA) can exacerbate these effects.

N,N-Dimethylcyclohexylamine (DMCHA) is essential to wear appropriate personal protective equipment, such as gloves and safety goggles, when handling N,N-Dimethylcyclohexylamine (DMCHA) to minimize skin and eye contact.
Inhalation of N,N-Dimethylcyclohexylamine (DMCHA) vapors or aerosols may cause irritation to the respiratory tract, leading to symptoms such as coughing, sore throat, and difficulty breathing.

Individuals with pre-existing respiratory conditions or sensitivity to chemical fumes may experience more severe respiratory effects.
Adequate ventilation and respiratory protection, such as respirators, should be used in areas where N,N-Dimethylcyclohexylamine (DMCHA) is handled or processed to reduce inhalation exposure.

N,N-DIMETHYLETHANOLAMINE (DEANOL)
DESCRIPTION:

N,N-Dimethylethanolamine (Deanol) is an organic compound with the formula (CH3)2NCH2CH2OH.
N,N-Dimethylethanolamine (Deanol) is bifunctional, containing both a tertiary amine and primary alcohol functional groups.
N,N-Dimethylethanolamine (Deanol) is a colorless viscous liquid.


CAS Number, 108-01-0
EC Number, 203-542-8
IUPAC Name:2-(dimethylamino)ethanol
Molecular Formula: C4H11NO

SYNONYMS OF N,N-DIMETHYLETHANOLAMINE (DEANOL):
Deanol; (2-Hydroxyethyl)dimethylamine; 2-(Dimethylamino)-1-ethanol; 2-(N,N-Dimethylamino)ethanol; 2-Dimethylaminoethanol; 2-Dwumetyloaminoetanolu [Polish]; Amietol M 21; Bimanol; DMAE; DMEA; Deanol; Dimethyl(2-hydroxyethyl)amine; Dimethyl(hydroxyethyl)amine; Dimethylaethanolamin [German]; Dimethylaminoaethanol [German]; Dimethylaminoethanol; Dimethylethanolamine; Dimethylmonoethanolamine; Ethanol, 2-(dimethylamino)-; Kalpur P; Liparon; N,N-Dimethyl-2-aminoethanol; N,N-Dimethyl-2-hydroxyethylamine; N,N-Dimethyl-N-(2-hydroxyethyl)amine; N,N-Dimethyl-N-(beta-hydroxyethyl)amine; N,N-Dimethylaminoethanol; N,N-Dimethylethanolamine; N-(2-Hydroxyethyl)dimethylamine; N-Dimethylaminoethanol; Norcholine; Propamine A; Texacat DME; Varesal; beta-Dimethylaminoethyl alcohol; beta-Hydroxyethyldimethylamine; [ChemIDplus] UN2051; UN2920,Deanol,Dimethyl ethanolamine,Dimethylaminoethanol,N,N-Dimethylaminoethanol,N,N-Dimethylethanolamine,Astyl,Deanol,Deanol,Deanol Bisorcate,Demanol,Demanyl,Dimethylaminoethanol,Dimethylethanolamine,N,N Dimethyl 2 hydroxyethylamine,N,N-Dimethyl-2-hydroxyethylamine,N,N-Dimethylethanolamine,2-(Dimethylamino)ethanol,Deanol,N,N-Dimethylethanolamine,108-01-0,Dimethylethanolamine,Dimethylaminoethanol,2-DIMETHYLAMINOETHANOL,Norcholine,DMAE,Bimanol,Liparon,Varesal,N,N-Dimethylaminoethanol,Propamine A,DMEA,Ethanol, 2-(dimethylamino)-,(2-Hydroxyethyl)dimethylamine,Kalpur P,Dimethylmonoethanolamine,Dimethylaminoaethanol,N,N-Dimethyl-2-hydroxyethylamine,Amietol M 21
N,N-Dimethyl-2-aminoethanol,N-Dimethylaminoethanol,Texacat DME,N,N-Dimethyl ethanolamine,2-(N,N-Dimethylamino)ethanol,Dimethyl(hydroxyethyl)amine,Dimethylaethanolamin,Dimethyl(2-hydroxyethyl)amine,2-(Dimethylamino)-1-ethanol,N-(2-Hydroxyethyl)dimethylamine,Demanol,Demanyl,N,N-Dimethyl-N-(2-hydroxyethyl)amine,(Dimethylamino)ethanol,beta-Hydroxyethyldimethylamine,beta-Dimethylaminoethyl alcohol,2-(Dimethylamino) ethanol,2-Dwumetyloaminoetanolu,2-Dimethylamino-ethanol,N,N-Dimethyl-N-(beta-hydroxyethyl)amine,NSC 2652,CCRIS 4802,N-(Dimethylamino)ethanol,Oristar dmae,HSDB 1329,N,N-Dimethyl(2-hydroxyethyl)amine,Tegoamin DMEA,EINECS 203-542-8,Dabco DMEA,UNII-2N6K9DRA24,2-(dimethylamino)ethan-1-ol,Deanol [BAN],BRN 1209235,2N6K9DRA24DIMETHYL MEA,AI3-09209,CHEBI:271436,NSC-2652,N,N'-Dimethylethanolamine,2-(dimethylamino)-ethanol(CH3)2NCH2CH2OH,CHEMBL1135,.beta.-(Dimethylamino)ethanol,.beta.-Hydroxyethyldimethylamine,DTXSID2020505,.beta.-Dimethylaminoethyl alcohol,NSC2652,EC 203-542-8,Phosphatidyl-N-dimethylethanolamine,Deanol (BAN),MFCD00002846,n-(2-hydroxyethyl)-n,n-dimethylamine,N,N-DIMETHYLAMINOETHANOL (DMAE),NCGC00159413-02,Tonibral,N,N-Dimethyl-N-(.beta.-hydroxyethyl)amine,DEANOL (MART.),DEANOL [MART.],DTXCID00505,rexolin,CAS-108-01-0,Dimethylaethanolamin [German],Dimethylamino ethanol,Dimethylaminoaethanol [German],2-Dwumetyloaminoetanolu [Polish],2-Dimethylamino ethanol,UN2051,Ethanol, 2-dimethylamino-,N,N-Dimethyl-N-ethanolamine,2-dimethylamino,N,N Dimethyl 2 hydroxyethylamine,Jeffcat DMEA,Dimethylethanoiamine,Toyocat –DMA,dimethyl ethanolamine,dimethyl-ethanolamine,DIMETHOL,Paresan (Salt/Mix),dimethyl ethanol amine,THANCAT DME,2-dimethyamino-ethanol,n,n-dimethylethanolamin,Biocoline (Salt/Mix),beta-dimethylaminoethanol,N,N dimethylaminoethanol,DEANOL [WHO-DD],DEANOL [MI],N,N-dimethyl-ethanolamine,N,N-dimethylamino ethanol,N,N-dimethylethanol amine,N,N-dimethylethanol-amine,(n,n-dimethylamino)ethanol,2-Hydroxyethyldimethylamine,2-Dimethylaminoethanol [UN2051] [Corrosive],beta-(Dimethylamino)ethanol,beta -(dimethylamino)ethanol,DIMETHYL MEA [INCI],Dimethylaminoaethanol(german),N,N-Dimethylethanolamine (2-Dimethylaminoethanol),Choline chloride (Salt/Mix),Luridin chloride (Salt/Mix),beta –hydroxyethyldimethylamine,N,N-Dimethylethanolamine/DMEA,beta -dimethylaminoethyl alcohol,DMAE1549,2-(N,N-dimethyl amino)ethanol,2-(N,N-dimethylamino) ethanol,N-hydroxyethyl-N,N-dimethylamine,2-(N,N-dimethyl amino) ethanol,beta -(dimethylamino)ethyl alcohol,2-hydroxy-N,N-dimethylethanaminium,B-DIMETHYLAMINOETHYL ALCOHOL,WLN: Q2N1 & 1,2,Dimethylaminoethanol, >=99.5%,BCP22017,CS-M3462,N,N-Dimethyl-beta-hydroxyethylamine,.beta.-(Dimethylamino)ethyl alcohol,N, N-Dimethyl(2-hydroxyethyl)amine,Tox21_113163,Tox21_201821,Tox21_302844,BDBM50060526,N,N-Dimethyl-beta –hydroxyethylamine,N,N-Dimethylaminoethanol, redistilled,2-(DIMETHYLAMINO)ETHYL ALCOHOL,AKOS000118738,N,N-Dimethyl-.beta.-hydroxyethylamine,DB13352,N,N-DIMETHYLETHANOLAMINE [HSDB]RP10040,UN 2051,N, N-Dimethyl-N-(2-hydroxyethyl)amine,NCGC00159413-03,NCGC00256454-01,NCGC00259370-01,BP-13447,N,N-Dimethyl-N-(beta -hydroxyethyl)amine,N, N-Dimethyl-N-(beta -hydroxyethyl)amine,D0649,NS00001173,D07777,DIMETHYLAMINOETHANOL, (CORROSIVE LIQUID),2-Dimethylaminoethanol [UN2051] [Corrosive],2-Dimethylaminoethanol, purum, >=98.0%,(GC),Q241049,2-Dimethylaminoethanol, analytical reference material,2-Dimethylaminoethanol, SAJ first grade, >=99.0%,W-108727,Z104473552,2-Dimethylaminoethanol, purified by redistillation, >=99.5%,InChI=1/C4H11NO/c1-5(2)3-4-6/h6H,3-4H2,1-2H,N,N-Dimethyl-2-hydroxyethylamine, N,N-Dimethylethanolamine, DMEA

N,N-Dimethylethanolamine (Deanol) is used in skin care products for improving skin tone and also taken orally as a nootropic.
N,N-Dimethylethanolamine (Deanol) is prepared by the ethoxylation of dimethylamine.

N,N-Dimethylethanolamine (Deanol) appears as a clear colorless liquid with a fishlike odor.
Flash point 105 °F. Less dense than water.
N,N-Dimethylethanolamine (Deanol) Vapors heavier than air.

N,N-Dimethylethanolamine (Deanol) Toxic oxides of nitrogen produced during combustion.
N,N-Dimethylethanolamine (Deanol) is Used to make other chemicals.


N,N-Dimethylethanolamine (Deanol) is a tertiary amine that is ethanolamine having two N-methyl substituents.
N,N-Dimethylethanolamine (Deanol) has a role as a curing agent and a radical scavenger.
N,N-Dimethylethanolamine (Deanol) is a tertiary amine and a member of ethanolamines.

N,N-Dimethylethanolamine (Deanol) is commonly referred to as 2-(dimethylamino)ethanol, dimethylaminoethanol (DMAE) or dimethylethanolamine (DMEA).
N,N-Dimethylethanolamine (Deanol) holds tertiary amine and primary alcohol groups as functional groups.
N,N-Dimethylethanolamine (Deanol) has been used in the treatment of attention deficit-hyperactivity disorder (ADHD), Alzheimer's disease, autism, and tardive dyskinesia.

N,N-Dimethylethanolamine (Deanol) has been also used as an ingredient in skin care, and in cognitive function- and mood-enhancing products.

N,N-Dimethylethanolamine (Deanol) is a transparent, pale yellow liquid and primary alcohol that is used as a building block for the synthesis of cationic flocculants and ion exchange resins.
N,N-Dimethylethanolamine (Deanol) is also used used as a chemical intermediate for pharmaceuticals, dyes, corrosion inhibitors, and emulsifiers and as an additive to boiler water, paint removers, and amino resins.

N,N-Dimethylethanolamine (Deanol) is a chemical that can be converted into choline.
Choline is involved in a series of reactions that form acetylcholine, a chemical that is found in the brain and other areas of the body.
Acetylcholine is a "neurotransmitter" that helps nerve cells communicate.


N,N-Dimethylethanolamine (Deanol) is used for attention deficit-hyperactivity disorder (ADHD), Alzheimer disease, autism, and other conditions, but there is no good scientific evidence to support these uses.

N,N-Dimethylethanolamine (Deanol) was previously sold by Riker Laboratories as the prescription drug Deaner.

N,N-Dimethylethanolamine (Deanol) was prescribed for the management of children with behavior problems and learning difficulties.
Deanol is not an approved food additive in the U.S., nor is it an orphan drug, as some advertising N,N-Dimethylethanolamine (Deanol).


Dimethylaminoethanol, also known as DMAE or dimethylethanolamine, is an organic compound.
N,N-Dimethylethanolamine (Deanol) also goes by the names of N,N-dimethyl-2-aminoethanol, beta-dimethylaminoethyl alcohol, beta-hydroxyethyldimethylamine and Deanol.
N,N-Dimethylethanolamine (Deanol) is a liquid with a color that ranges from clear to pale yellow.


Industrial uses:
N,N-Dimethylethanolamine (Deanol) is used as a curing agent for polyurethanes and epoxy resins.
N,N-Dimethylethanolamine (Deanol) is a precursor to other chemicals, such as the nitrogen mustard 2-dimethylaminoethyl chloride.
The acrylate ester, dimethylaminoethyl acrylate is used as a flocculating agent.
Related compounds are used in gas purification, e.g. removal of hydrogen sulfide from sour gas streams.

Dimethylaminoethanol, also known as DMAE or dimethylethanolamine, is an organic compound.
N,N-Dimethylethanolamine (Deanol) also goes by the names of N,N-dimethyl-2-aminoethanol, beta-dimethylaminoethyl alcohol, beta-hydroxyethyldimethylamine and Deanol.
N,N-Dimethylethanolamine (Deanol) is a liquid with a color that ranges from clear to pale yellow.

Dimethylaminoethanol is used as a curing agent for polyurethanes and epoxy resins.
N,N-Dimethylethanolamine (Deanol) is used to the synthesis of dyestuffs, textile auxiliaries, pharmaceuticals, emulsifiers, and corrosion inhibitors.
Also N,N-Dimethylethanolamine (Deanol) is an additive to paint removers, boiler water, and amino resins.

Biochemical Precursor Dimethylaminoethanol is related to choline and is a biochemical precursor to the neurotransmitter acetylcholine, and found naturally in fishes like sardines and anchovies.
N,N-Dimethylethanolamine (Deanol) is reported to have nootropic effects, although research on this chemical has found both positive and negative potential results.

N,N-Dimethylethanolamine (Deanol) is believed that dimethylaminoethanol is methylated to produce choline in the brain
N,N-Dimethylethanolamine (Deanol) is known that dimethylaminoethanol is processed by the liver into choline; however, the choline molecule is charged and cannot pass the blood-brain barrier.


Human uses:
The bitartrate salt of DMAE, i.e. N,N-dimethylethanolamine bitartrate, is sold as a dietary supplement.
N,N-Dimethylethanolamine (Deanol) is a white powder providing 37% DMAE.
Animal tests show possible benefit for improving spatial memory and working memory



APPLICATIONS OF N,N-DIMETHYLETHANOLAMINE (DEANOL):
N,N-Dimethylethanolamine (Deanol) may be employed as a ligand in the copper-catalyzed amination of aryl bromides and iodides.

The principal applications for N,N-Dimethylethanolamine (Deanol) include:
Flocculents
N,N-Dimethylethanolamine (Deanol) is a key intermediate in the production of dimethylaminoethyl-(meth)acrylate.
The water-soluble polymers produced from this ester, mostly by copolymerisation with acrylamide, are useful as flocculents.

Pulp and paper chemicals
The dry strength or wet strength of paper is increased by adding a homopolymer of dimethylaminoethyl(meth)acrylate to the unbleached kraft paper.

Ion exchange resins
Anion exchange resins can be prepared by reacting tertiary amines like N,N-Dimethylethanolamine (Deanol) or trimethylamine with the chloromethylated vinyl or styrene resin.

Increased exchange capacity is obtained by reacting a cross-linked polymer, containing haloalkyl functions, with an amine.

The anion exchange membranes are aminated with N,N-Dimethylethanolamine (Deanol).

Polyurethane
In the production of PU foam for insulating purposes, the use of N,N-Dimethylethanolamine (Deanol) is a practical and effective way of reducing the total formula cost.

Resins
Epoxy
N,N-Dimethylethanolamine (Deanol) is an effective and versatile curing agent for epoxy resins.
N,N-Dimethylethanolamine (Deanol) also acts as viscosity reducing agent for resinous polyamides and other viscous hardeners.
N,N-Dimethylethanolamine (Deanol) is also an extremely good wetting agent for various filters in epoxy formulations.


Acrylic
N,N-Dimethylethanolamine (Deanol) improves the acid-dyeing properties of acrylonitrile polymers by copolymerisation of N,N-Dimethylethanolamine (Deanol) esters.

Water-soluble DMAE salts are used to improve the behaviour of coatings and films to make them water-resistant or provide specific desired sensitivity to water.

Textiles – leather
The acid-dyeing capability of polyacrylonitrile is improved by copolymerisation of the acrylonitrile with N,N-Dimethylethanolamine (Deanol) esters, such as dimethylaminoethyl acrylate.

Cellulose modified with the homopolymer of dimethylaminoethyl methacrylate can be dyed with ester salts of a leuco vat dye.

The impregnation of cellulose with polydimethylaminoethyl methacrylate also improves the gas-fading resistance of the fabric.

Long-chain alkylphosphates of DMAE form anti-static agents for non-cellulosic hydrophobic textile materials.

Paints, coatings and inks
N,N-Dimethylethanolamine (Deanol) is excellent for neutralising free acidity in water-soluble coating resins.
The resin can be acrylic, alkyd or styrene-maleic.
N,N-Dimethylethanolamine (Deanol) is often preferred to triethylamine when lower volatility is required, as in electrodeposition.
N,N-Dimethylethanolamine (Deanol) also improves pigment wettability.

Some synthetic enamels with a metallic appearance can be prepared from dimethylaminoethyl methacrylate polymers.

In flexographic inks DMAE can be used to solubilize resins and inoxes.

The adhesion of latex coatings can be improved by copolymerisation of the acrylic monomers with dimethylaminoethyl acrylate.

Surfactants – detergents
Alkylethanolamine salts of anionic surfactants are generally much more soluble than the corresponding sodium salts, both in water and oil systems.
N,N-Dimethylethanolamine (Deanol) can be an excellent starting material in the production of shampoos from fatty acids.
The fatty acid soaps are especially effective as wax emulsifiers for water-resistant floor polishes.


N,N-Dimethylethanolamine (Deanol) titanates, zirconates and other group IV-A metal esters are useful as dispersing agents for polymers, hydrocarbons and waxes in aqueous or organic solvent systems.

N,N-Dimethylethanolamine (Deanol) is commonly referred to as 2-(dimethylamino)ethanol, dimethylaminoethanol (DMAE) or dimethylethanolamine (DMEA).
N,N-Dimethylethanolamine (Deanol) holds tertiary amine and primary alcohol groups as functional groups.
N,N-Dimethylethanolamine (Deanol) has been used in the treatment of attention deficit-hyperactivity disorder (ADHD), Alzheimer's disease, autism, and tardive dyskinesia.
N,N-Dimethylethanolamine (Deanol) has been also used as an ingredient in skin care, and in cognitive function- and mood-enhancing products.



CHEMICAL AND PHYSICAL PROPERTIES OF N,N-DIMETHYLETHANOLAMINE (DEANOL)
Chemical formula, C4H11NO
Molar mass, 89.138 g•mol−1
Appearance, Colourless liquid
Odor, Fishy, ammoniacal
Density, 890 mg mL−1
Melting point, −59.00 °C; −74.20 °F; 214.15 K
Boiling point, 134.1 °C; 273.3 °F; 407.2 K
log P, −0.25
Vapor pressure, 816 Pa (at 20 °C)
Acidity (pKa), 9.23 (at 20 °C)[1]
Basicity (pKb), 4.77 (at 20 °C)
Refractive index (nD), 1.4294
Molecular Weight
89.14 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
XLogP3-AA
-0.4
Computed by XLogP3 3.0 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
1
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
2
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
2
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
89.084063974 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
89.084063974 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
23.5Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
6
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
28.7
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
0
Computed by PubChem
Undefined Atom Stereocenter Count
0
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
1
Computed by PubChem
Compound Is Canonicalized
Yes
CAS, 108-01-0
Molecular Formula, C4H11NO
Molecular Weight (g/mol), 89.14
MDL Number, MFCD00002846
InChI Key, UEEJHVSXFDXPFK-UHFFFAOYSA-NShow More
Synonym, 2-dimethylamino ethanol, n,n-dimethylethanolamine, deanol, dimethylaminoethanol, dimethylethanolamine, norcholine, dmae, dmea, bimanol, liparonShow Less
PubChem CID, 7902
ChEBI, CHEBI:271436
IUPAC Name, 2-(dimethylamino)ethanol
SMILES, CN(C)CCO
CAS Min %, 98.5
CAS Max %, 100.0
Melting Point, -70.0°C
Color, Colorless to Yellow
Density, 0.8880g/mL
Boiling Point, 139.0°C
Flash Point, 40°C
Infrared Spectrum, Authentic
Assay Percent Range, 98.5% min. (GC)
Packaging, Glass bottle
Linear Formula, HOCH2CH2N(CH3)2
Refractive Index, 1.4290 to 1.4300
Quantity, 1 L
Beilstein, 04, 276
Merck Index, 15, 2845
Specific Gravity, 0.888
Solubility Information, Solubility in water: miscible. Other solubilities: miscible with alcohol and ether
Viscosity, 3.8 mPa.s (20°C)
Formula Weight, 89.14
Percent Purity, 99%
Physical Form, Liquid
Chemical Name or Material, N, N-Dimethylethanolamine
Vapor Pressure
3.18 mm Hg
Odor Threshold Low
0.015 ppm
Odor Threshold High
0.06 ppm
Lethal Concentration
LC50 (rat) = 1,641 ppm/4h
Explanatory Notes
Flash point = 105 deg F; Odor threshold from CHEMINFO; VP from HSDB;
high ambient temp required
Properties
assay, ≥
assay range, 99.5%
bromine number, 134-136
brush size diam. × l, ?C (lit.)
depth, 0.886
depth × h × w, g/mL
depth × overall h, at 20
depth × width, ?C (lit.)
Description, N,N-DIMETHYLETHANOLAMINE
inlet and outlet nptm × nptm, 1S/C4H11NO/c1-5(2)3-4-6/h6H3-4H21-2H3
inlet and outlet size, UEEJHVSXFDXPFK-UHFFFAOYSA-N
MDM Code, 471453-500ML
Material Number, 471453
Business Unit, 774
Shipping Mode, AIR
MRP Type, YP
Local HS Code, 29221990
Legacy, SIGMA
Plant, 6311
Sales Org, 6304
CAS Number, 108-01-0
Molecular Weight, 89.14 g/mol
Molecular Formula, C4H11NO
XLogP3, -0.4
Hydrogen Bond Donor Count, 1
Hydrogen Bond Acceptor Count, 2
Rotatable Bond Count, 2
Exact Mass, 89.084063974 g/mol
Monoisotopic Mass, 89.084063974 g/mol
Topological Polar Surface Area, 23.5 Ų
Heavy Atom Count, 6
Formal Charge, 0
Complexity, 28.7
Isotope Atom Count, 0
Defined Atom Stereocenter Count, 0
Undefined Atom Stereocenter Count, 0
Defined Bond Stereocenter Count, 0
Undefined Bond Stereocenter Count, 0
Covalently Bonded Unit Count, 1
Melting point , −70 °C(lit.)
Boiling point , 134-136 °C(lit.)
density , 0.886 g/mL at 20 °C(lit.)
vapor pressure , 100 mm Hg ( 55 °C)
refractive index , n20/D 1.4294(lit.)
Fp , 105 °F
storage temp. , Flammables area
Water Solubility , miscible
FreezingPoint , -59.0ºC
Merck , 14,2843
BRN , 1209235
Stability:, Stable. Flammable. Incompatible with oxidizing agents, copper, copper alloys, zinc, acids, galvanised iron. Hygroscopic.
CAS DataBase Reference, 108-01-0(CAS DataBase Reference)
NIST Chemistry Reference, Ethanol, 2-(dimethylamino)-(108-01-0)
EPA Substance Registry System, Ethanol, 2-(dimethylamino)-(108-01-0)





SAFETY INFORMATION ABOUT N,N-DIMETHYLETHANOLAMINE (DEANOL):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.


N,N-DIMETHYLETHANOLAMINE (DMAE OR DMEA)
N,N-Dimethylethanolamine (DMAE or DMEA) is a tertiary amine that is ethanolamine having two N-methyl substituents.
N,N-Dimethylethanolamine (DMAE or DMEA) has a role as a curing agent and a radical scavenger.
N,N-Dimethylethanolamine (DMAE or DMEA) is a tertiary amine and a member of ethanolamines.

CAS: 108-01-0
MF: C4H11NO
MW: 89.14
EINECS: 203-542-8

Synonyms
(CH3)2NCH2CH2OH;Amietol M 21;amietolm21;beta-Hydroxyethyldimethylamine;Bimanol;Dabco DMEA;Dimethylaethanolamin;dimethylamino-2ethanol;2-(Dimethylamino)ethanol;Deanol;N,N-Dimethylethanolamine;108-01-0;Dimethylethanolamine;Dimethylaminoethanol;2-DIMETHYLAMINOETHANOL
;Norcholine;DMAE;Bimanol;Liparon;Varesal;N,N-Dimethylaminoethanol;Propamine A;DMEA
;Ethanol, 2-(dimethylamino)-;(2-Hydroxyethyl)dimethylamine;Kalpur P;Dimethylmonoethanolamine
;Dimethylaminoaethanol;N,N-Dimethyl-2-hydroxyethylamine;Amietol M 21;N,N-Dimethyl-2-aminoethanol;N-Dimethylaminoethanol;Texacat DME;N,N-Dimethyl ethanolamine;2-(N,N-Dimethylamino)ethanol;Dimethyl(hydroxyethyl)amine;Dimethylaethanolamin;Dimethyl(2-hydroxyethyl)amine;2-(Dimethylamino)-1-ethanol;N-(2-Hydroxyethyl)dimethylamine;Demanol
;Demanyl;N,N-Dimethyl-N-(2-hydroxyethyl)amine;(Dimethylamino)ethanol;beta-Hydroxyethyldimethylamine;beta-Dimethylaminoethyl alcohol;2-(Dimethylamino) ethanol;2-Dwumetyloaminoetanolu;2-Dimethylamino-ethanol;N,N-Dimethyl-N-(beta-hydroxyethyl)amine
;NSC 2652;CCRIS 4802;N-(Dimethylamino)ethanol;Oristar dmae;HSDB 1329;N,N-Dimethyl(2-hydroxyethyl)amine;Tegoamin DMEA;EINECS 203-542-8;Dabco DMEA;UNII-2N6K9DRA24;2-(dimethylamino)ethan-1-ol;Deanol [BAN];BRN 1209235;2N6K9DRA24;DIMETHYL MEA;AI3-09209
;CHEBI:271436;NSC-2652;N,N'-Dimethylethanolamine;2-(dimethylamino)-ethanol;(CH3)2NCH2CH2OH;CHEMBL1135;.beta.-(Dimethylamino)ethanol;.beta.-Hydroxyethyldimethylamine;DTXSID2020505;.beta.-Dimethylaminoethyl alcohol;NSC2652
;EC 203-542-8;Phosphatidyl-N-dimethylethanolamine;Deanol (BAN);MFCD00002846;n-(2-hydroxyethyl)-n,n-dimethylamine;N,N-DIMETHYLAMINOETHANOL (DMAE);NCGC00159413-02
;Tonibral;N,N-Dimethyl-N-(.beta.-hydroxyethyl)amine;DEANOL (MART.);DEANOL [MART.];DTXCID00505
;rexolin;CAS-108-01-0;Dimethylaethanolamin [German];Dimethylamino ethanol;Dimethylaminoaethanol [German];2-Dwumetyloaminoetanolu [Polish];2-Dimethylamino ethanol;UN2051;Ethanol, 2-dimethylamino-;N,N-Dimethyl-N-ethanolamine
;2-dimethylamino;N,N Dimethyl 2 hydroxyethylamine;Jeffcat DMEA;Dimethylethanoiamine
;Toyocat -DMA;dimethyl ethanolamine;dimethyl-ethanolamine;DIMETHOL;Paresan (Salt/Mix)
;dimethyl ethanol amine;THANCAT DME;2-dimethyamino-ethanol;n,n-dimethylethanolamin
;Biocoline (Salt/Mix);beta-dimethylaminoethanol;N,N dimethylaminoethanol;DEANOL [WHO-DD]
;DEANOL [MI];N,N-dimethyl-ethanolamine;N,N-dimethylamino ethanol;N,N-dimethylethanol amine
;N,N-dimethylethanol-amine;(n,n-dimethylamino)ethanol;2-Hydroxyethyldimethylamine;2-Dimethylaminoethanol [UN2051] [Corrosive];beta-(Dimethylamino)ethanol;beta -(dimethylamino)ethanol;DIMETHYL MEA [INCI];Dimethylaminoaethanol(german);N,N-Dimethylethanolamine (2-Dimethylaminoethanol);Choline chloride (Salt/Mix);Luridin chloride (Salt/Mix);beta -hydroxyethyldimethylamine;N,N-Dimethylethanolamine/DMEA;beta -dimethylaminoethyl alcohol;DMAE1549;2-(N,N-dimethyl amino)ethanol;2-(N,N-dimethylamino) ethanol;N-hydroxyethyl-N,N-dimethylamine;2-(N,N-dimethyl amino) ethanol;beta -(dimethylamino)ethyl alcohol;2-hydroxy-N,N-dimethylethanaminium;B-DIMETHYLAMINOETHYL ALCOHOL;WLN: Q2N1 & 1;2-Dimethylaminoethanol, >=99.5%;BCP22017;CS-M3462;N,N-Dimethyl-beta-hydroxyethylamine;.beta.-(Dimethylamino)ethyl alcohol;N, N-Dimethyl(2-hydroxyethyl)amine
;Tox21_113163;Tox21_201821;Tox21_302844;BDBM50060526;N,N-Dimethyl-beta -hydroxyethylamine
;N,N-Dimethylaminoethanol, redistilled;2-(DIMETHYLAMINO)ETHYL ALCOHOL;AKOS000118738
;N,N-Dimethyl-.beta.-hydroxyethylamine;DB13352;N,N-DIMETHYLETHANOLAMINE [HSDB];RP10040
;UN 2051;N, N-Dimethyl-N-(2-hydroxyethyl)amine;NCGC00159413-03;NCGC00256454-01
;NCGC00259370-01;BP-13447;N,N-Dimethyl-N-(beta -hydroxyethyl)amine;N, N-Dimethyl-N-(beta -hydroxyethyl)amine;D0649;NS00001173;D07777;DIMETHYLAMINOETHANOL, (CORROSIVE LIQUID)
;2-Dimethylaminoethanol [UN2051] [Corrosive];2-Dimethylaminoethanol, purum, >=98.0% (GC)
;Q241049;2-Dimethylaminoethanol, analytical reference material;2-Dimethylaminoethanol, SAJ first grade, >=99.0%;W-108727;Z104473552;2-Dimethylaminoethanol, purified by redistillation, >=99.5%;InChI=1/C4H11NO/c1-5(2)3-4-6/h6H,3-4H2,1-2H;N,N-Dimethyl-2-hydroxyethylamine, N,N-Dimethylethanolamine, DMEA

N,N-Dimethylethanolamine (DMAE or DMEA) is a colorless liquidwith a pungent odor.
Odor threshold: 0.25 ppm.
Molecularweight 5 89.16; Boiling point =133℃; Freezing/Meltingpoint=259℃; Flash point =41℃ (oc); Autoignitiontemperature 5=295℃.
Explosive limits: LEL 5=1.6%;UEL 5=11.9%.
Hazard Identification (based on NFPA-704M Rating System): Health 2, Flammability 2, Reactivity 0.Soluble in water.
A clear colorless liquid with a fishlike odor.
Flash point 105°F.
Less dense than water.
Vapors heavier than air.
Toxic oxides of nitrogen produced during combustion.
Used to make other chemicals.

N,N-Dimethylethanolamine (DMAE or DMEA) is an organic compound with the formula (CH3)2NCH2CH2OH.
N,N-Dimethylethanolamine (DMAE or DMEA) is bifunctional, containing both a tertiary amine and primary alcohol functional groups.
N,N-Dimethylethanolamine (DMAE or DMEA) is a colorless viscous liquid.
N,N-Dimethylethanolamine (DMAE or DMEA) is used in skin care products for improving skin tone and also taken orally as a nootropic.
N,N-Dimethylethanolamine (DMAE or DMEA) is prepared by the ethoxylation of dimethylamine.
N,N-Dimethylethanolamine (DMAE or DMEA), is a naturally occurring compound found in small amounts in the brain and various types of seafood.
N,N-Dimethylethanolamine (DMAE or DMEA) is often used as an ingredient in dietary supplements and skincare products due to its potential cognitive and skin benefits.
N,N-Dimethylethanolamine (DMAE or DMEA) is also used as a corrosion inhibitor, anti-scaling agent, paint additive, coating additive, and solids separation agent.

N,N-Dimethylethanolamine (DMAE or DMEA) is a colorless liquid that has a molecular weight of 78.1 g/mol and a boiling point of 176.1 °C.
N,N-Dimethylethanolamine (DMAE or DMEA) can be found in many household products as well as cosmetics, pharmaceuticals, and chemical manufacturing.
N,N-Dimethylethanolamine (DMAE or DMEA) is a precursor to acetaldehyde and acetic acid, which are important intermediates in the production of polymers such as nylon.
N,N-Dimethylethanolamine (DMAE or DMEA) can also be used to synthesize other chemicals such as dimethylformamide, ethylene glycol, and methyl methacrylate.
This chemical reacts with calcium to form insoluble calcium 2-(dimethylamino)ethanolate (Ca(DMAE)).
This reaction is reversible and the equilibrium can be shifted by changing the pH or adding another reactant such as hydrogen peroxide or hydroxide ions.

N,N-Dimethylethanolamine (DMAE or DMEA) Chemical Properties
Melting point: −70 °C(lit.)
Boiling point: 134-136 °C(lit.)
Density: 0.886 g/mL at 20 °C(lit.)
Vapor density: 3.03 (vs air)
Vapor pressure: 100 mm Hg ( 55 °C)
Refractive index: n20/D 1.4294(lit.)
Fp: 105 °F
Storage temp.: Store below +30°C.
Solubility alcohol: miscible(lit.)
Form: Liquid
pka: pK1:9.26(+1) (25°C)
Color: Clear colorless to pale yellow
Odor: Amine like
PH Range: 10.5 - 11.0 at 100 g/l at 20 °C
PH: 10.5-11 (100g/l, H2O, 20℃)
Explosive limit: 1.4-12.2%(V)
Water Solubility: miscible
FreezingPoint: -59.0℃
Sensitive: Hygroscopic
Merck: 14,2843
BRN: 1209235
Stability: Stable. Flammable. Incompatible with oxidizing agents, copper, copper alloys, zinc, acids, galvanised iron. Hygroscopic.
InChIKey: UEEJHVSXFDXPFK-UHFFFAOYSA-N
LogP: -0.55 at 23℃
CAS DataBase Reference: 108-01-0(CAS DataBase Reference)
NIST Chemistry Reference: N,N-Dimethylethanolamine (DMAE or DMEA)(108-01-0)
EPA Substance Registry System: N,N-Dimethylethanolamine (DMAE or DMEA) (108-01-0)

colorless or slightly yellow liquid with ammonia odor.
N,N-Dimethylethanolamine (DMAE or DMEA) is miscible with water, ethanol, benzene, ether and acetone.
N,N-Dimethylethanolamine (DMAE or DMEA) is a colorless liquid with a pungent odor.
N,N-Dimethylethanolamine (DMAE or DMEA) has a melting point of -70°C and a boiling point of 134-136°C.
The density is 0.886 g/mL at 20°C.
N,N-Dimethylethanolamine (DMAE or DMEA) is miscible with alcohol.

Uses
N,N-Dimethylethanolamine (DMAE or DMEA) is also known as dimethylaminoethanol.
Studies indicate skin-firming properties, and an ability to reduce the appearance of fine lines and wrinkles as well as dark circles under the eyes.
N,N-Dimethylethanolamine (DMAE or DMEA) is considered anti-aging, and antiinflammatory, and has exhibited free-radical scavenging activity.
N,N-Dimethylethanolamine (DMAE or DMEA) is used as corrosion inhibitor, anti-scaling agent, paint additive, coating additive and solids separation agent.
N,N-Dimethylethanolamine (DMAE or DMEA) is also used as an intermediate for active pharmaceutical ingredients and dyes.

N,N-Dimethylethanolamine (DMAE or DMEA) serves as a curing agent for polyurethanes and epoxy resins.
Further, N,N-Dimethylethanolamine (DMAE or DMEA) is used as an additive to boiler water.
In addition to this, N,N-Dimethylethanolamine (DMAE or DMEA) is used therapeutically as a CNS stimulant.
N,N-Dimethylethanolamine (DMAE or DMEA) may be employed as a ligand in the copper-catalyzed amination of aryl bromides and iodides.
The bitartrate salt of N,N-Dimethylethanolamine (DMAE or DMEA), i.e. N,N-dimethylethanolamine bitartrate, is sold as a dietary supplement.
N,N-Dimethylethanolamine (DMAE or DMEA) is a white powder providing 37% DMAE.
Animal tests show possible benefit for improving spatial memory and working memory.

Industrial uses
N,N-Dimethylethanolamine (DMAE or DMEA)l is used as a chemical intermediate for antihistamines and local anesthetics; as a catalyst for curing epoxy resins and polyurethanes; and as a pH control agent for boiler water treatment.
However, N,N-Dimethylethanolamine (DMAE or DMEA) in the salt form, (i.e. dimethylaminoethanol acetamidobenzoate) is primarily utilized therapeutically as an antidepressant.
N,N-Dimethylethanolamine (DMAE or DMEA) is used as a curing agent for polyurethanes and epoxy resins.
N,N-Dimethylethanolamine (DMAE or DMEA) is a precursor to other chemicals, such as the nitrogen mustard 2-dimethylaminoethyl chloride.
The acrylate ester, N,N-Dimethylethanolamine (DMAE or DMEA) is used as a flocculating agent.
Related compounds are used in gas purification, e.g. removal of hydrogen sulfide from sour gas streams.

Preparation
The synthesis of N,N-Dimethylethanolamine (DMAE or DMEA) by the ethylene oxide method is obtained by the ammonification of dimethylamine with ethylene oxide, which is distilled, refined and dehydrated.
Synthesis of N,N-Dimethylethanolamine (DMAE or DMEA) can be accomplished from equimolar amounts of ethylene oxide and dimethylamine.
N,N-Dimethylethanolamine (DMAE or DMEA) is synthesized for various purposes.
N,N-Dimethylethanolamine (DMAE or DMEA) is used as an intermediate for active pharmaceutical ingredients and dyes.
N,N-Dimethylethanolamine (DMAE or DMEA) serves as a curing agent for polyurethanes and epoxy resins.
The synthesis of N,N-Dimethylethanolamine (DMAE or DMEA) involves a linear formula: (CH3)2NCH2CH2OH.

Reactivity Profile
N,N-Dimethylethanolamine (DMAE or DMEA) is an aminoalcohol.
Amines are chemical bases.
They neutralize acids to form salts plus water.
These acid-base reactions are exothermic.
The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base.
Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
N,N-Dimethylethanolamine (DMAE or DMEA) may react vigorously with oxidizing materials.

Health Hazard
N,N-Dimethylethanolamine (DMAE or DMEA) is classified as a mild skin irritant and a severe eye irritant.
Doses as high as 1200 mg daily produce no serious side effects and a single dose of 2500 mg taken in a suicide attempt had no adverse effects.
Inhalation of the vapor or mist can cause irritation to the upper respiratory tract.
Asthmatic symptoms have been reported.
Extremely irritating; may cause permanent eye injury.
Corrosive; will cause severe skin damage with burns and blistering.
Ingestion may cause damage to the mucous membranes and gastrointestinal tract.
No reports were found in the literature regarding carcinogenic or mutagenic potential.
N,N-DIMETHYLETHANOLAMINE (DMEA)
N,N-dimethylethanolamine (DMEA) is colorless or slightly yellow liquid with ammonia odor.
N,N-dimethylethanolamine (DMEA) is miscible with water, ethanol, benzene, ether and acetone.
N,N-dimethylethanolamine (DMEA) is a tertiary amine that is ethanolamine having two N-methyl substituents.

CAS Number: 108-01-0
Molecular Formula: C4H11NO
Molecular Weight: 89.14
EINECS Number: 203-542-8

2-(Dimethylamino)ethanol, Deanol, N,N-Dimethylethanolamine, 108-01-0, Dimethylethanolamine, Dimethylaminoethanol, 2-DIMETHYLAMINOETHANOL, Norcholine, DMAE, Bimanol, Liparon, Varesal, N,N-Dimethylaminoethanol, Propamine A, DMEA, Ethanol, 2-(dimethylamino)-, (2-Hydroxyethyl)dimethylamine, Kalpur P, Dimethylmonoethanolamine, Dimethylaminoaethanol, N,N-Dimethyl-2-hydroxyethylamine, Amietol M 21, N,N-Dimethyl-2-aminoethanol, N-Dimethylaminoethanol, Texacat DME, N,N-Dimethyl ethanolamine, 2-(N,N-Dimethylamino)ethanol, Dimethyl(hydroxyethyl)amine, Dimethylaethanolamin, Dimethyl(2-hydroxyethyl)amine, 2-(Dimethylamino)-1-ethanol, N-(2-Hydroxyethyl)dimethylamine, Demanol, Demanyl, N,N-Dimethyl-N-(2-hydroxyethyl)amine, (Dimethylamino)ethanol, beta-Hydroxyethyldimethylamine, beta-Dimethylaminoethyl alcohol, 2-(Dimethylamino) ethanol, 2-Dwumetyloaminoetanolu, 2-Dimethylamino-ethanol, N,N-Dimethyl-N-(beta-hydroxyethyl)amine, NSC 2652, CCRIS 4802, N-(Dimethylamino)ethanol, Oristar dmae, HSDB 1329, N,N-Dimethyl(2-hydroxyethyl)amine, Tegoamin DMEA, EINECS 203-542-8, Dabco DMEA, UNII-2N6K9DRA24, 2-(dimethylamino)ethan-1-ol, Deanol [BAN], BRN 1209235, 2N6K9DRA24, DIMETHYL MEA, AI3-09209, CHEBI:271436, NSC-2652, N,N'-Dimethylethanolamine, 2-(dimethylamino)-ethanol, (CH3)2NCH2CH2OH, CHEMBL1135, .beta.-(Dimethylamino)ethanol, .beta.-Hydroxyethyldimethylamine, DTXSID2020505, .beta.-Dimethylaminoethyl alcohol, NSC2652, EC 203-542-8, Phosphatidyl-N-dimethylethanolamine, Deanol (BAN), MFCD00002846, n-(2-hydroxyethyl)-n,n-dimethylamine, N,N-DIMETHYLAMINOETHANOL (DMAE), NCGC00159413-02, Tonibral, N,N-Dimethyl-N-(.beta.-hydroxyethyl)amine, DEANOL (MART.), DEANOL [MART.], DTXCID00505, rexolin, CAS-108-01-0, Dimethylaethanolamin [German], Dimethylamino ethanol, Dimethylaminoaethanol [German], 2-Dwumetyloaminoetanolu [Polish], 2-Dimethylamino ethanol, UN2051, Ethanol, 2-dimethylamino-, N,N-Dimethyl-N-ethanolamine, 2-dimethylamino, N,N Dimethyl 2 hydroxyethylamine, Jeffcat DMEA, Dimethylethanoiamine, Toyocat -DMA, dimethyl ethanolamine, dimethyl-ethanolamine, DIMETHOL, Paresan (Salt/Mix), dimethyl ethanol amine, THANCAT DME, 2-dimethyamino-ethanol, n,n-dimethylethanolamin, Biocoline (Salt/Mix), beta-dimethylaminoethanol, N,N dimethylaminoethanol, DEANOL [WHO-DD], DEANOL [MI], N,N-dimethyl-ethanolamine, N,N-dimethylamino ethanol, N,N-dimethylethanol amine, N,N-dimethylethanol-amine, (n,n-dimethylamino)ethanol, 2-Hydroxyethyldimethylamine, 2-Dimethylaminoethanol [UN2051] [Corrosive], beta-(Dimethylamino)ethanol, beta -(dimethylamino)ethanol, DIMETHYL MEA [INCI], Dimethylaminoaethanol(german), N,N-Dimethylethanolamine (2-Dimethylaminoethanol), Choline chloride (Salt/Mix), Luridin chloride (Salt/Mix), beta -hydroxyethyldimethylamine, N,N-Dimethylethanolamine/DMEA, beta -dimethylaminoethyl alcohol, DMAE1549, 2-(N,N-dimethyl amino)ethanol, 2-(N,N-dimethylamino) ethanol, N-hydroxyethyl-N,N-dimethylamine, 2-(N,N-dimethyl amino) ethanol, beta -(dimethylamino)ethyl alcohol, 2-hydroxy-N,N-dimethylethanaminium, B-DIMETHYLAMINOETHYL ALCOHOL, WLN: Q2N1 & 1, 2-Dimethylaminoethanol, >=99.5%, BCP22017, CS-M3462, N,N-Dimethyl-beta-hydroxyethylamine, .beta.-(Dimethylamino)ethyl alcohol, N, N-Dimethyl(2-hydroxyethyl)amine, Tox21_113163, Tox21_201821, Tox21_302844, BDBM50060526, N,N-Dimethyl-beta -hydroxyethylamine, N,N-Dimethylaminoethanol, redistilled, 2-(DIMETHYLAMINO)ETHYL ALCOHOL, AKOS000118738, N,N-Dimethyl-.beta.-hydroxyethylamine, DB13352, N,N-DIMETHYLETHANOLAMINE [HSDB], RP10040, UN 2051, N, N-Dimethyl-N-(2-hydroxyethyl)amine, NCGC00159413-03, NCGC00256454-01, NCGC00259370-01, BP-13447, N,N-Dimethyl-N-(beta -hydroxyethyl)amine, N, N-Dimethyl-N-(beta -hydroxyethyl)amine, D0649, NS00001173, D07777, DIMETHYLAMINOETHANOL, (CORROSIVE LIQUID), 2-Dimethylaminoethanol [UN2051] [Corrosive],

N,N-dimethylethanolamine (DMEA) has a role as a curing agent and a radical scavenger.
N,N-dimethylethanolamine (DMEA) is a tertiary amine and a member of ethanolamines.
The synthesis of N,N-dimethylethanolamine (DMEA) by the ethylene oxide method is obtained by the ammonification of dimethylamine with ethylene oxide, which is distilled, refined and dehydrated.

N,N-dimethylethanolamine (DMEA) is an aminoalcohol. Amines are chemical bases.
They neutralize acids to form salts plus water.
These acid-base reactions are exothermic.

The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base.
Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

N,N-dimethylethanolamine (DMEA) may react vigorously with oxidizing materials.
N,N-dimethylethanolamine (DMEA) is an organic compound with the formula (CH3)2NCH2CH2OH.
N,N-dimethylethanolamine (DMEA) is bifunctional, containing both a tertiary amine and primary alcohol functional groups.

N,N-dimethylethanolamine (DMEA) is a colorless viscous liquid.
N,N-dimethylethanolamine (DMEA) is used in skin care products for improving skin tone and also taken orally as a nootropic.
N,N-dimethylethanolamine (DMEA) is prepared by the ethoxylation of dimethylamine.

N,N-dimethylethanolamine (DMEA) is used as a curing agent for polyurethanes and epoxy resins.
N,N-dimethylethanolamine (DMEA) is a precursor to other chemicals, such as the nitrogen mustard 2-dimethylaminoethyl chloride.
The acrylate ester, N,N-dimethylethanolamine (DMEA) acrylate is used as a flocculating agent.

N,N-dimethylethanolamine (DMEA) is an amino alcohol.
N,N-dimethylethanolamine (DMEA) is the main product formed during the amination of ethylene glycol by dimethylamine on alumina supported copper in a continuous fixed-bed reactor.
N,N-dimethylethanolamine (DMEA) has been reported to be the putative precursor of acetylcholine.

Its effect as a skin-firming and anti-wrinkle agent has been studied.
Microwave spectrum of N,N-dimethylethanolamine (DMEA) has been investigated.
Its effect as an organic additive on deposition and anti-reflective properties of porous CaF2 has been studied.

Removal of the benzyl ester groups by transesterification with N,N-dimethylethanolamine (DMEA) from benzyl protected tripeptides has been reported.
N,N-dimethylethanolamine (DMEA) facilitates the synthesis of the neurotransmitter acetylcholine in the brain and also stimulates the synthesis of phosphatidylcholine.
N,N-dimethylethanolamine (DMEA) is assumed that DMEA is methylated to choline in the brain.

N,N-dimethylethanolamine (DMEA) is transformed into choline by the liver but the choline molecule is too large to easily pass through the blood-brain barrier.
N,N-dimethylethanolamine (DMEA) is a tertiary amine with the chemical formula C4H11NO.
N,N-dimethylethanolamine (DMEA) is also known as dimethylaminoethanol or dimethylethanolamine.

N,N-dimethylethanolamine (DMEA) is a clear, colorless liquid with a fishy odor and is miscible with water and most organic solvents.
N,N-dimethylethanolamine (DMEA) is commonly used as a precursor in the synthesis of various chemicals, including pesticides, pharmaceuticals, and corrosion inhibitors.
Additionally, N,N-dimethylethanolamine (DMEA) is utilized as a catalyst in the production of polyurethanes and as a stabilizer in the formulation of certain products, such as metalworking fluids and fuels.

N,N-dimethylethanolamine (DMEA) may be employed as a ligand in the copper-catalyzed amination of aryl bromides and iodides.
N,N-dimethylethanolamine (DMEA) is a precursor to other chemicals, such as the nitrogen mustard 2-dimethylaminoethyl chloride.
The acrylate ester is used as a flocculating agent.

Related compounds are used in gas purification, e.g. removal of hydrogen sulfide from sour gas streams.
The bitartrate salt of N,N-dimethylethanolamine (DMEA), i.e. 2-dimethylaminoethanol (+)-bitartrate, is sold as a dietary supplement.
N,N-dimethylethanolamine (DMEA) is a white powder providing 37% DMAE.

Animal tests show possible benefit for improving spatial memory and working memory.
N,N-dimethylethanolamine (DMEA) is used as a curing agent for polyurethanes and epoxy resins.
Moreover, N,N-dimethylethanolamine (DMEA) is used as a chemical intermediate for pharmaceuticals, dyes, corrosion inhibitors, and emulsifiers.

N,N-dimethylethanolamine (DMEA) is used as an additive to boiler water, paint removers, and amino resins.
N,N-dimethylethanolamine (DMEA) is Has been used therapeutically as a CNS stimulant.
N,N-dimethylethanolamine (DMEA) is a transparent, pale yellow liquid and primary alcohol that is used as a building block for the synthesis of cationic flocculants and ion exchange resins.

Also, N,N-dimethylethanolamine (DMEA) is used as a chemical intermediate for pharmaceuticals, dyes, corrosion inhibitors, and emulsifiers and as an additive to boiler water, paint removers, and amino resins.
N,N-dimethylethanolamine (DMEA) is an amine neutralizer.
N,N-dimethylethanolamine (DMEA) can provide pH stability, promote color acceptance, and also can be used as co-dispersant and wetting agent.

The N,N-dimethylethanolamine (DMEA) Market size is expected to develop revenue and exponential market growth at a remarkable CAGR during the forecast period from 2023–2030.
The growth of the market can be attributed to the increasing demand for N,N-dimethylethanolamine (DMEA) owning to the Pharmaceuticals, Paint & Coatings, Pulp & Paper, Mining, Oil & Gas, Other Applications across the global level.
The report provides insights regarding the lucrative opportunities in the N,N-dimethylethanolamine (DMEA) Market at the country level.

The report also includes a precise cost, segments, trends, region, and commercial development of the major key players globally for the projected period.
N,N-dimethylethanolamine (DMEA) report represents gathered information about a market within an industry or various industries.
The N,N-dimethylethanolamine (DMEA) report includes analysis in terms of both quantitative and qualitative data with a forecast period of the report extending from 2023 to 2030.

The report is prepared to take into consideration various factors such as Product pricing, Product or services penetration at both country and regional levels, Country GDP, market dynamics of parent market & child markets, End application industries, major players, consumer buying behavior, economic, political, social scenarios of countries, many others.
The report is divided into various segments to offer a detailed analysis of the market from every possible aspect of the market.
N,N-dimethylethanolamine (DMEA) is a clear, viscous liquid with an amine-like odor that is widely used in the water treatment industry as a polyurethane catalyst, as an intermediate in textile chemicals, ion exchange resins and emulsifying agents and also in a wide range of coatings applications.

N,N-dimethylethanolamine (DMEA) is used as an intermediate in the synthesis of pharmaceutical compounds.
N,N-dimethylethanolamine (DMEA) is utilized in the formulation of corrosion inhibitors for metals, particularly in the oil and gas industry.
N,N-dimethylethanolamine (DMEA) serves as a catalyst in the production of polyurethanes, which are widely used in the manufacturing of foams, coatings, adhesives, and sealants.

N,N-dimethylethanolamine (DMEA) is employed as a stabilizer in the formulation of metalworking fluids to prevent corrosion and improve lubricity.
N,N-dimethylethanolamine (DMEA) is sometimes added to fuels as an additive to improve combustion efficiency and reduce emissions.
N,N-dimethylethanolamine (DMEA) can be used in the production of surfactants, which are essential components in various household and industrial cleaning products.

N,N-dimethylethanolamine (DMEA) is found in some cosmetics and personal care products due to its emulsifying properties.
N,N-dimethylethanolamine (DMEA) is used in the textile industry as an intermediate in the production of certain dyes and finishing agents.
N,N-dimethylethanolamine (DMEA) is utilized in the electroplating industry as an additive in plating baths to enhance the quality and uniformity of metal deposits.

N,N-dimethylethanolamine (DMEA) is used in textile printing processes as a dye-fixing agent to improve color fastness and durability of printed fabrics.
N,N-dimethylethanolamine (DMEA) finds application in the leather industry as a neutralizing agent in the tanning process to adjust pH levels and improve leather quality.
N,N-dimethylethanolamine (DMEA) is incorporated into printing inks as a solvent or a viscosity modifier to achieve desired printing characteristics.

N,N-dimethylethanolamine (DMEA) is used in wood preservation treatments as a component of wood preservatives to protect against decay and insect damage.
N,N-dimethylethanolamine (DMEA) is employed as a reagent in various chemical reactions and laboratory procedures, particularly in organic synthesis.
N,N-dimethylethanolamine (DMEA) is used as an antistatic agent in certain products to reduce static electricity buildup on surfaces.

N,N-dimethylethanolamine (DMEA) serves as a reactant or a catalyst in the production of synthetic resins, such as epoxy resins and polyesters.
N,N-dimethylethanolamine (DMEA) may be used as an excipient in pharmaceutical formulations to improve solubility or stability of active ingredients.
N,N-dimethylethanolamine (DMEA) is added to certain fuels as an additive to improve combustion efficiency and reduce engine emissions.

Melting point: −70 °C(lit.)
Boiling point: 134-136 °C(lit.)
Density: 0.886 g/mL at 20 °C(lit.)
vapor density: 3.03 (vs air)
vapor pressure: 100 mm Hg ( 55 °C)
refractive index: n20/D 1.4294(lit.)
Flash point: 105 °F
storage temp.: Store below +30°C.
solubility: alcohol: miscible(lit.)
form: Liquid
pka: pK1:9.26(+1) (25°C)
color: Clear colorless to pale yellow
Odor:Amine like
PH Range: 10.5 - 11.0 at 100 g/l at 20 °C
PH: 10.5-11 (100g/l, H2O, 20℃)
explosive limit 1.4-12.2%(V)
Water Solubility: miscible
FreezingPoint: -59.0℃
Sensitive: Hygroscopic
Merck: 14,2843
BRN: 1209235
Stability: Stable. Flammable. Incompatible with oxidizing agents, copper, copper alloys, zinc, acids, galvanised iron. Hygroscopic.
InChIKey: UEEJHVSXFDXPFK-UHFFFAOYSA-N
LogP: -0.55 at 23℃

N,N-dimethylethanolamine (DMEA) belongs to a unique class of disubstituted amides with utility in coatings, household,industrial and institutional applications.
N,N-dimethylethanolamine (DMEA) displays a broad range of properties, including excellent solvency, a low VOC content, as well as heat and hydrolysis stability.
N,N-dimethylethanolamine (DMEA) is an intermediate used in the production of flocculation agents, ion exchange resins, dyes, corrosion inhibitors, water based coatings, pharmaceuticals, crop protection agents, pesticides, additives for textiles, hardeners for epoxy resins and polyurethane catalyst.

N,N-dimethylethanolamine (DMEA) is used in the following products: coating products, adhesives and sealants, fillers, putties, plasters, modelling clay, non-metal-surface treatment products, inks and toners, anti-freeze products, leather treatment products, lubricants and greases, polishes and waxes and textile treatment products and dyes.
Other release to the environment of N,N-dimethylethanolamine (DMEA) is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).
N,N-dimethylethanolamine (DMEA) is also known as dimethylaminoethanol.

Studies indicate skin-firming properties, and an ability to reduce the appearance of fine lines and wrinkles as well as dark circles under the eyes.
N,N-dimethylethanolamine (DMEA) is considered anti-aging, and antiinflammatory, and has exhibited free-radical scavenging activity.
N,N-dimethylethanolamine (DMEA) is used as corrosion inhibitor, anti-scaling agent, paint additive, coating additive and solids separation agent.

Also, N,N-dimethylethanolamine (DMEA) is used as an intermediate for active pharmaceutical ingredients and dyes.
N,N-dimethylethanolamine (DMEA) serves as a curing agent for polyurethanes and epoxy resins.
Further, N,N-dimethylethanolamine (DMEA) is used as an additive to boiler water.

In addition to this, N,N-dimethylethanolamine (DMEA) is used therapeutically as a CNS stimulant.
N,N-dimethylethanolamine (DMEA) may be employed as a ligand in the copper-catalyzed amination of aryl bromides and iodides.
Also, N,N-dimethylethanolamine (DMEA) is used as a chemical intermediate for antihistamines and local anesthetics; as a catalyst for curing epoxy resins and polyurethanes; and as a pH control agent for boiler water treatment.

However, N,N-dimethylethanolamine (DMEA) in the salt form, (i.e. dimethylaminoethanol acetamidobenzoate) is primarily utilized therapeutically as an antidepressant.
N,N-dimethylethanolamine (DMEA) is a precursor of acetylcholine.
Microwave spectral studies on N,N-dimethylethanolamine (DMEA) have reported the following values; the rotational constants (MHz) A = 5814.0(2), B = 2214.54(2), and C = 2037.96(2) and a dipole moment of 2.56 D, with a, b, and c components (D) of 2.27(2), 0.3(1), and 1.16(5), respectively.

N,N-dimethylethanolamine (DMEA) is an organic compound with the formula (CH3)2NCH2CH2OH.
Additionally, N,N-dimethylethanolamine (DMEA) is bifunctional, containing both a tertiary amine and primary alcohol functional groups.
N,N-dimethylethanolamine (DMEA) is a colorless viscous liquid.

Furthermore, N,N-dimethylethanolamine (DMEA) is used in skin care products for improving skin tone and also taken orally as a nootropic.
N,N-dimethylethanolamine (DMEA) is prepared by the ethoxylation of dimethylamine.
N,N-dimethylethanolamine (DMEA) is a clear colorless liquid with a fishlike odor.

In addition to that, N,N-dimethylethanolamine (DMEA) is commonly referred to as 2-(dimethylamino)ethanol, dimethylaminoethanol (DMAE) or dimethylethanolamine (DMEA).
N,N-dimethylethanolamine (DMEA) holds tertiary amine and primary alcohol groups as functional groups.
N,N-dimethylethanolamine (DMEA) has been used in the treatment of attention deficit-hyperactivity disorder (ADHD), Alzheimer's disease, autism, and tardive dyskinesia.

N,N-dimethylethanolamine (DMEA) has been also used as an ingredient in skin care, and in cognitive function- and moodenhancing products.
N,N-dimethylethanolamine (DMEA) appears as a clear colorless liquid with a fishlike odor.
Flash point of N,N-dimethylethanolamine (DMEA) is 105°F.

N,N-dimethylethanolamine (DMEA) is less dense than water
N,N-dimethylethanolamine (DMEA) is employed in the formulation of adhesives, where it acts as a curing agent or a stabilizer.
N,N-dimethylethanolamine (DMEA) is utilized in the formulation of paints and coatings as a coalescing agent to enhance film formation and improve the performance of the final product.

N,N-dimethylethanolamine (DMEA) is added to emulsions and dispersions to stabilize the system and improve its shelf life.
N,N-dimethylethanolamine (DMEA) finds application in water treatment processes as a neutralizing agent or pH adjuster.
N,N-dimethylethanolamine (DMEA) is used in the polymer industry for the production of various polymer resins and compounds.

N,N-dimethylethanolamine (DMEA) is sometimes used in photographic developers as a pH buffer or an emulsifying agent.
N,N-dimethylethanolamine (DMEA) is incorporated into fabric softeners to impart softness and reduce static cling.
N,N-dimethylethanolamine (DMEA) is used in agriculture as an additive in pesticide formulations or as a solvent for agricultural chemicals.

N,N-dimethylethanolamine (DMEA) is employed in the rubber industry as a curing agent or a processing aid.
N,N-dimethylethanolamine (DMEA) is used in research laboratories for various chemical reactions and experiments.
N,N-dimethylethanolamine (DMEA) can be found in some cosmetics and personal care products as a pH adjuster or an emulsifying agent.

N,N-dimethylethanolamine (DMEA) is investigated for potential biomedical applications, including drug delivery systems and tissue engineering.
N,N-dimethylethanolamine (DMEA) has been postulated that dimethylaminoethanol undergoes endogenous methylation.
After intravenous treatment of mice with [14C]-labeled N,N-dimethylethanolamine (DMEA) in the brain, dimethylaminoethanol yielded phosphoryldimethylaminoethanol andphosphatidyldimethylaminoethanol.

Acid-soluble and lipid cholines derived from N,N-dimethylethanolamine (DMEA) also were found in brain.
While examining the pharmacokinetics of the maleate acid of [14C]-N,N-dimethylethanolamine (DMEA) in rats, observed that dimethylaminoethanol was metabolized in the phospholipid cycle and produced metabolites such as phosphoryldimethylaminoethanolamine, and glycerophosphatidylcholine.
In kainic-acid lesioned rats, N,N-dimethylethanolamine (DMEA) was converted to a substance which cross-reacted in the radioenzymatic assay for acetylcholine.

They also showed that brain levels of N,N-dimethylethanolamine (DMEA) increased to a maximum at 1-2 h and decreased afterwards, whereas concentrations of phosphatidylethanolamine increased continuously throughout the 7 h observation period.
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids.

If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water.
If this chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped.
Transfer promptly to a medicalfacility.

If victim is conscious, administer water ormilk. Do not induce vomiting.
Medical observation isrecommended for 2448 h after breathing overexposure, aspulmonary edema may be delayed.
As first aid for pulmonary edema, a doctor or authorized paramedic mayconsider administering a corticosteroid spray.

Uses:
N,N-dimethylethanolamine (DMEA) is also known as dimethylaminoethanol.
Studies indicate skin-firming properties, and an ability to reduce the appearance of fine lines and wrinkles as well as dark circles under the eyes.
N,N-dimethylethanolamine (DMEA) is considered anti-aging, and antiinflammatory, and has exhibited free-radical scavenging activity.

N,N-dimethylethanolamine (DMEA) is used as corrosion inhibitor, anti-scaling agent, paint additive, coating additive and solids separation agent.
N,N-dimethylethanolamine (DMEA) is also used as an intermediate for active pharmaceutical ingredients and dyes.
N,N-dimethylethanolamine (DMEA) serves as a curing agent for polyurethanes and epoxy resins.

Further, N,N-dimethylethanolamine (DMEA) is used as an additive to boiler water.
In addition to this, N,N-dimethylethanolamine (DMEA) is used therapeutically as a CNS stimulant.
N,N-dimethylethanolamine (DMEA) may be employed as a ligand in the copper-catalyzed amination of aryl bromides and iodides.

N,N-dimethylethanolamine (DMEA) is used as an intermediate + buffering agent in the synthesis of coatings.
N,N-dimethylethanolamine (DMEA) is used in the synthesis of cation exchange resins, as a stabilizer for coatings, fuel oil additives, boiler scale inhibitor and an important auxiliary agent for polyurethane processing,
N,N-dimethylethanolamine (DMEA) is corrosive to metals and may cause damage to skin, eyes, and respiratory tract upon contact.

N,N-dimethylethanolamine (DMEA) can lead to burns, irritation, and tissue damage.
N,N-dimethylethanolamine (DMEA) is a skin and eye irritant. Prolonged or repeated exposure may result in redness, itching, and dermatitis. Inhalation of vapors can irritate the respiratory system.
Some individuals may develop sensitization upon repeated exposure to N,N-dimethylethanolamine (DMEA), leading to allergic reactions such as dermatitis.

N,N-dimethylethanolamine (DMEA) may pose environmental hazards if released into the environment.
N,N-dimethylethanolamine (DMEA) can contaminate soil, water bodies, and air, affecting aquatic life and ecosystems.
N,N-dimethylethanolamine (DMEA) is flammable and can form explosive vapor-air mixtures.

N,N-dimethylethanolamine (DMEA) should be stored away from heat, sparks, and open flames.
Inhalation of N,N-dimethylethanolamine (DMEA) vapors may cause headache, dizziness, nausea, and respiratory irritation.
Ingestion can lead to gastrointestinal irritation and vomiting.

Long-term exposure to N,N-dimethylethanolamine (DMEA) may result in adverse health effects, including liver and kidney damage, respiratory disorders, and central nervous system effects.
N,N-dimethylethanolamine (DMEA) may react with strong oxidizing agents, acids, and alkalis, leading to hazardous chemical reactions or releases of toxic gases.
Proper personal protective equipment, including gloves, safety goggles, and respiratory protection, should be worn when handling N,N-dimethylethanolamine (DMEA) to minimize exposure risks.

Regulatory requirements for handling, storage, transportation, and disposal of N,N-dimethylethanolamine (DMEA) may apply due to its hazardous nature.
Compliance with relevant regulations is essential to prevent environmental contamination and ensure worker safety.
N,N-dimethylethanolamine (DMEA) may exhibit toxicity upon ingestion, inhalation, or skin absorption.

Acute exposure to high concentrations can result in systemic toxicity and adverse health effects.
Regulatory agencies may establish occupational exposure limits for N,N-dimethylethanolamine (DMEA) to protect workers from adverse health effects.
Exposure to concentrations exceeding these limits should be avoided.

Animal studies suggest that N,N-dimethylethanolamine (DMEA) may have reproductive and developmental toxicity effects.
Pregnant women and individuals of childbearing age should take precautions to minimize exposure.
There is limited evidence regarding the carcinogenic potential of N,N-dimethylethanolamine (DMEA).

However, some studies suggest a possible association with certain types of cancer.
Further research is needed to assess its carcinogenic risk in humans.
N,N-dimethylethanolamine (DMEA) may persist in the environment and undergo transformation into potentially more hazardous compounds.

Proper disposal methods should be followed to minimize environmental contamination.
When exposed to high temperatures or in the presence of oxidizing agents, N,N-dimethylethanolamine (DMEA) may decompose and release hazardous gases, such as nitrogen oxides and carbon monoxide.
N,N-dimethylethanolamine (DMEA) is flammable and can form explosive mixtures with air.

Adequate ventilation and fire control measures should be implemented to prevent fire and explosion hazards.
N,N-dimethylethanolamine (DMEA) may react violently with certain chemicals, such as strong acids, bases, and oxidizing agents.
Proper segregation and storage practices should be followed to prevent inadvertent reactions.

In the event of a spill, leak, or release of N,N-dimethylethanolamine (DMEA), appropriate emergency response procedures should be followed, including containment, cleanup, and notification of relevant authorities.
Training and Education: Workers handling N,N-dimethylethanolamine (DMEA) should receive adequate training on its hazards, safe handling practices, and emergency procedures to minimize risks and ensure their safety.

Safety Profile:
Moderately toxic by ingestion, inhalation, skin contact, intraperitoneal, and subcutaneous routes.
A skin and severe eye irritant.
N,N-dimethylethanolamine (DMEA) is used medically as a central nervous system stimulant.

Flammable liquid when exposed to heat or flame; can react vigorously with oxidzing materials.
Ignites spontaneously in contact with cellulose nitrate of high surface area.
To fight fire, use alcohol foam, foam, CO2, dry chemical.

Health Hazard:
N,N-dimethylethanolamine (DMEA) is classified as a mild skin irritant and a severe eye irritant.
Doses as high as 1200 mg daily produce no serious side effects and a single dose of 2500 mg taken in a suicide attempt had no adverse effects.
Inhalation of the vapor or mist can cause irritation to the upper respiratory tract.

Asthmatic symptoms have been reported. Extremely irritating; may cause permanent eye injury.
Corrosive; will cause severe skin damage with burns and blistering.
Ingestion may cause damage to the mucous membranes and gastrointestinal tract.


N,N-DIMETHYLFORMAMIDE
DESCRIPTION:
N,N-Dimethylformamide [HCON(CH₃)₂] is a colorless to pale-yellow liquid with a faint odor.
N,N-Dimethylformamide can harm the eyes, skin, lungs, liver, and heart.
Workers may be harmed from exposure to N,N-Dimethylformamide.

CAS 68-12-2
EC Number 200-679-5
Chemical formula HCON(CH₃)₂


N,n-dimethylformamide appears as a water-white liquid with a faint fishy odor.
N,n-dimethylformamide has Flash point 136 °F.
N,n-dimethylformamide is Slightly less dense than water.

Vapors of N,n-dimethylformamide is heavier than air.
N,n-dimethylformamide is Toxic by inhalation or skin absorption.
N,n-dimethylformamide May irritate eyes.

N,N-dimethylformamide is a member of the class of formamides that is formamide in which the amino hydrogens are replaced by methyl groups.
N,n-dimethylformamide has a role as a polar aprotic solvent, a hepatotoxic agent and a geroprotector.
N,n-dimethylformamide is a volatile organic compound and a member of formamides.

N,n-dimethylformamide is functionally related to a formamide.
N,n-dimethylformamide is used as an industrial solvent and in the production of fibers, films, and surface coatings.
Acute (short-term) exposure to N,n-dimethylformamide has been observed to damage the liver in animals and in humans.
Symptoms of acute exposure in humans include abdominal pain, nausea, vomiting, jaundice, alcohol intolerance, and rashes.

Chronic (long-term) occupational exposure to N,n-dimethylformamide by inhalation has resulted in effects on the liver and digestive disturbances in workers.
Human studies suggested a possible association between N,n-dimethylformamide exposure and testicular cancer, but further studies failed to confirm this relationship.
EPA has not classified N,n-dimethylformamide with respect to its carcinogenicity.

N,N-Dimethylformamide (DMF) is the commonly employed solvent for chemical reactions.
N,N-Dimethylformamide is a useful solvent employed for the isolation of chlorophyll from plant tissues.
N,N-Dimethylformamide is widely employed reagent in organic synthesis.

N,N-Dimethylformamide plays multiple roles in various reactions such as solvent, dehydrating agent, reducing agent as well as catalyst.
N,N-Dimethylformamide is a multipurpose building block for the synthesis of compounds containing O, -CO, -NMe2, -CONMe2, -Me, -CHO as functional groups.

N,N-Dimethylformamide is a polar solvent commonly used in organic synthesis.
N,N-Dimethylformamide also acts as a multipurpose precursor for formylation, amination, aminocarbonylation, amidation and cyanation reactions

USES OF N,N-DIMETHYLFORMAMIDE:
N,N-Dimethylformamide is primarily used as an industrial solvent.
N,N-Dimethylformamide solutions are used to process polymer fibers, films, and surface coatings; to permit easy spinning of acrylic fibers; to produce wire enamels, and as a crystallization medium in the pharmaceutical industry.

N,N-Dimethylformamide is used in many industries.
N,N-Dimethylformamide is used as an industrial solvent and in the manufacture of synthetic fibers, plastics, and other chemicals.
Some examples of workers at risk of being exposed to N,N-Dimethylformamide include the following:
• Factory workers involved in plastics manufacturing
• Employees exposed to certain industrial solvents
• Workers involved in acrylic fiber spinning
• Employees who work in pharmaceutical production

APPLICATIONS OF N,N-DIMETHYLFORMAMIDE:
N,N-Dimethylformamide (anhydrous) has been used as solvent for the synthesis of cytotoxic luteinizing hormone-releasing hormone (LH-RH) conjugate AN-152 (a chemotherapeutic drug) and fluorophore C625 [4-(N,N-diphenylamino)-4′-(6-O-hemiglutarate)hexylsulfinyl stilbene].
N,N-Dimethylformamide may be employed as solvent medium for the various organic reduction reactions.
N,N-Dimethylformamide has been used as a solvent in the following processes:

Multi-step synthesis of L-azidohomoalanine (L-Aha) during the substitution of the mesylate by sodium azide.
Synthesis of phosphine-FLAG, a detection reagent for metabolic labeling of glycans.
Synthesis of per-O-acetylated 6-azidofucose, a per-O-acetylated azido sugar




SAFETY INFORMATION ABOUT N,N-DIMETHYLFORMAMIDE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product

Hazard Summary:
N,N-Dimethylformamide is used as an industrial solvent and in the production of fibers, films, and surface coatings.
Acute (short-term) exposure to N,N-Dimethylformamide has been observed to damage the liver in animals and in humans.
Symptoms of acute exposure in humans include abdominal pain, nausea, vomiting, jaundice, alcohol intolerance, and rashes.

Chronic (long-term) occupational exposure to N,N-Dimethylformamide by inhalation has resulted in effects on the liver and digestive disturbances in workers.
Human studies suggested a possible association between N,N-Dimethylformamide exposure and testicular cancer, but further studies failed to confirm this relationship.
EPA has not classified N,N-Dimethylformamide with respect to its carcinogenicity.







CHEMICAL AND PHYSICAL PROPERTIES OF N,N-DIMETHYLFORMAMIDE:
CAS number 68-12-2
EC index number 616-001-00-X
EC number 200-679-5
Hill Formula C₃H₇NO
Chemical formula HCON(CH₃)₂
Molar Mass 73.09 g/mol
HS Code 2924 19 00
Boiling point 153 °C (1013 hPa)
Density 0.944 g/cm3 (25 °C)
Explosion limit 2.2 - 16 %(V)
Flash point 57.5 °C
Ignition temperature 410 °C
Melting Point -61 °C (External MSDS)
pH value 7 (200 g/l, H₂O, 20 °C)
Vapor pressure 3.77 hPa (20 °C)
Solubility 1000 g/l soluble
Autoignition Temperature 833 °F
Identity (IR) complying
Assay (GC) Min. 99.0 %
Water (Karl Fischer) Max. 0.1 %
Vapor Pressure 2.7 mmHg ( 20 °C)
Explosion Limit 15.2 %
Refractive Index n20/D 1.430(lit.)
Molecular Weight 73.09 g/mol
XLogP3 -1
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 1
Rotatable Bond Count 0
Exact Mass 73.052763847 g/mol
Monoisotopic Mass 73.052763847 g/mol
Topological Polar Surface Area 20.3Ų
Heavy Atom Count 5
Formal Charge 0
Complexity 33.9
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

Specifications:
Purity (GC) ≥ 99.9 %
Identity (IR) conforms
Color ≤ 10 Hazen
Acidity ≤ 0.0005 meq/g
Alkalinity ≤ 0.0002 meq/g
Amines (Dimethylamine) ≤ 10 ppm
Evaporation residue ≤ 10
Water ≤ 300 ppm
Purity (GC) ≥ 99.8 %
Identity (IR) conforms
Appearance clear
Colour ≤ 10 Hazen
Titrable acid ≤ 0.0005 meq/g
Titrable base ≤ 0.003 meq/g
Density (d 20 °C/20 °C) 0.949 - 0.952
Refractive index (n 20/D) 1.429 - 1.431
Boiling point 152 - 154 °C
Al (Aluminium) ≤ 0.00005 %
B (Boron) ≤ 0.000002 %
Ba (Barium) ≤ 0.00001 %
Ca (Calcium) ≤ 0.00005 %
Cd (Cadmium) ≤ 0.000005 %
Co (Cobalt) ≤ 0.000002 %
Cr (Chromium) ≤ 0.000002 %
Cu (Copper) ≤ 0.000002 %
Fe (Iron) ≤ 0.00001 %
Mg (Magnesium) ≤ 0.00001 %
Mn (Manganese) ≤ 0.000002 %
Ni (Nickel) ≤ 0.000002 %
Pb (Lead) ≤ 0.00001 %
Sn (Tin) ≤ 0.00001 %
Zn (Zinc) ≤ 0.00001 %
Evaporation residue ≤ 0.001 %
Water ≤ 0.10 %

SYNONYMS OF N,N-DIMETHYLFORMAMIDE:
DMF
N,N-Dimethylmethanamide
Formic acid dimethylamide
DIMETHYL FORMAMIDE
DIMETHYLFORMAMIDE
DMF
DMF (AMIDE)
DMFA
FORMYLDIMETHYLAMINE
N,N-DIMETHYLFORMAMIDE
N,N-DIMETHYLMETHANAMIDE
N-FORMYLDIMETHYLAMINE
NCI-C60913
NSC 5356
U-4224
N,N-DIMETHYLFORMAMIDE
Dimethylformamide
68-12-2
Dimethyl formamide
N,N-Dimethylmethanamide
N-Formyldimethylamine
Formamide, N,N-dimethyl-
Dimethylformamid
DMF
DMFA
Dimetilformamide
Dwumetyloformamid
Formyldimethylamine
N,N-Dimethyl formamide
Dimetylformamidu
DMF (amide)
Dimethylforamide
NCI-C60913
N,N Dimethylformamide
Dimethylamid kyseliny mravenci
Caswell No. 366A
dimethyl-Formamide
N,N-Dimethylformamid
N,N-Dimetilformamida
HSDB 78
CCRIS 1638
DTXSID6020515
U-4224
Dimetylformamidu [Czech]
Dimethylformamid [German]
Dimetilformamide [Italian]
Dwumetyloformamid [Polish]
NSC 5356
NSC-5356
Formic acid, amide, N,N-dimethyl-
EINECS 200-679-5
EPA Pesticide Chemical Code 366200
UNII-8696NH0Y2X
N,N-Dimetilformamida [Spanish]
CHEBI:17741
AI3-03311
n,n-dimethyl-Formamide
N, N-dimethylformamide
NSC5356
N,N'-Dimethylformamide
N,N- Dimethylformamide
8696NH0Y2X
N,N-Dimethylformaldehyde
N, N-dimethyl formamide
Dimethylformamide, N,N-
MFCD00003284
UN2265
n,n-dimethylformamide-1-d
Dimethylamid kyseliny mravenci [Czech]
DTXCID20515
EC 200-679-5
n,n,dimethylformamide
DIMETHYLFORMAMIDE (MART.)
DIMETHYLFORMAMIDE [MART.]
N,N-Dimethylformamide, HPLC Grade
N,N-DIMETHYLFORMAMIDE (IARC)
N,N-DIMETHYLFORMAMIDE [IARC]
CAS-68-12-2
N,N-Dimethylformamide, for HPLC, >=99.9%
N,N-Dimethylformamide, ACS reagent, >=99.8%
dimethlforamide
dimethlformamide
dimethyformamide
dimetylformamide
dimehtylformamide
dimethlyformamide
dimethyiformamide
dimethy formamide
dimethy1formamide
dimethyl foramide
dimethyl formamid
dimehtylformarnide
dimethylformarnide
dimethylforrnamide
dirnethylformamide
di-methylformamide
dimethylf ormamide
dimethylform amide
dimethylform-amide
dimethylformamid e
dimethylformamide-
dirnethylformarnide
n-dimethylformamide
dimethyl form-amide
dimethyl- formamide
dimethylfor- mamide
DMF,SP Grade
N,n-dimethylforamide
formamide, dimethyl-
N,N-dimethlformamide
N,N-dimethyformamide
N,N-dimetylformamide
n,n.dimethylformamide
N,N'dimethylformamide
N,N-dimethvlformamide
N.N-dimethylformamide
HCONMe2
Formamide,N-dimethyl-
N, N-dimethylforamide
N,N'-dimethylforamide
N,N-dimethl formamide
N,N-dimethy formamide
N,N-dimethyl foramide
N,N-dimethyl formamid
N,N-dimethylformarnide
N,N-dimethylforrnamide
N,N-dimetyl formamide
N,N-dirnethylformamide
n,n,-dimethylformamide
Dimethylformamide, DMF
DMF, Dimethylformamide
N, N dimethylformamide
N,N -dimethylformamide
N,N dimethyl formamide
N,N' dimethylformamide
N,N-di methylformamide
N,N-di-methylformamide
N,N-dime-thylformamide
N,N-dimehtyl formamide
N,N-dimethylfor mamide
N,N-dimethylfor-mamide
N,N-dimethylform-amide
N,N-dimethylformamide-
DMF (CHRIS Code)
N,N-di-methylforrnamide
Dimethyl Fornamide,(S)
DMF (dimethylformamide)
n,n,-dimethyl formamide
N, N'-dimethylformamide
N, N- dimethylformamide
N, N-di-methylformamide
N, N-dimethyl-formamide
N,N- dimethyl formamide
N,N-di-methyl formamide
N,N-di-methyl-formamide
N,N-dimethyl -formamide
N,N-dimethyl- formamide
Dimethylformamide (DMFA)
N, N-dimethylformaldehyde
Dimethylformamide (N,N-)
bmse000709
D0E1KX
Formamida, n, n-dimetil-
D.M.F
Formamide, N, N-dimethyl-
HCON(CH3)2
Dynasolve 100 (Salt/Mix)
BIDD:ER0600
WLN: VHN1&1
CHEMBL268291
D.M.F.
N,N-Dimethylformamide, 99.8%
N,N-Dimethylformamide, anhydrous
N,N-Dimethylformamide HPLC grade
N,N-Dimethylformamide, ACS grade
N,N-DIMETHYLFORMAMIDE [MI]
CS-CZ-00065
Dimethylformamide Reagent Grade ACS
Tox21_201259
Tox21_300039
N,N-DIMETHYLFORMAMIDE [HSDB]
N,N-Dimethylformamide, biotech grade
NA2265
s6192
STL264197
N,N-Dimethylformamide, LR, >=99%
AKOS000121096
FORMIN ACID,AMIDE,N,N-DIMETHYL
DB01844
LS-1577
N,N-DIMETHYLFORMAMIDE [USP-RS]
N,N-DIMETHYLFORMAMIDE [WHO-DD]
UN 2265
N,N-Dimethylformamide, p.a., 99.8%
USEPA/OPP Pesticide Code: 366200
N,N-Dimethylformamide, AR, >=99.5%
NCGC00090785-01
NCGC00090785-02
NCGC00090785-03
NCGC00090785-04
NCGC00090785-05
NCGC00254093-01
NCGC00258811-01
N,N-dimethylformamide; dimethyl formamide
Dimethylformamide, n,n- Reagent Grade ACS
N,N-Dimethylformamide, analytical standard
N,N-Dimethylformamide, anhydrous, 99.8%
D0722
D0939
FT-0629532
FT-0629533
FT-0639029
FT-0696040
N,N-Dimethylformamide, anhydrous, amine free
N,N-Dimethylformamide, for HPLC, >=99.5%
C03134
N,N-Dimethylformamide, Spectrophotometric Grade
N,N-Dimethylformamide, AldraSORB(TM), 99.8%
N,N-Dimethylformamide, ReagentPlus(R), >=99%
A836012
N,N-Dimethylformamide, biotech. grade, >=99.9%
Q409298
N,N-Dimethylformamide [UN2265] [Flammable liquid]
N,N-Dimethylformamide, p.a., ACS reagent, 99.8%
N,N-Dimethylformamide, SAJ first grade, >=99.0%
N,N-Dimethylformamide [UN2265] [Flammable liquid]
N,N-Dimethylformamide, anhydrous, ZerO2(TM), 99.8%
N,N-Dimethylformamide, for molecular biology, >=99%
N,N-Dimethylformamide, JIS special grade, >=99.5%
N,N-Dimethylformamide, UV HPLC spectroscopic, 99.7%
Z220615596
N,N-Dimethylformamide, ACS spectrophotometric grade, >=99.8%
N,N-Dimethylformamide HPLC, UV-IR min. 99.9%, isocratic grade
N,N-Dimethylformamide, Vetec(TM) reagent grade, anhydrous, >=99.8%
Dimethylformamide, Pharmaceutical Secondary Standard; Certified Reference Material
N,N-Dimethylformamide, p.a., ACS reagent, reag. ISO, reag. Ph. Eur., 99.8%
N,N-Dimethylformamide, puriss. p.a., ACS reagent, reag. Ph. Eur., >=99.8% (GC)
N,N-Dimethylformamide, suitable for neutral marker for measuring electroosmotic flow (EOF), ~99%



N,N-DIMETHYL-N-ETHANOLAMINE
N,N-Dimethyl-N-ethanolamine is colorless or slightly yellow liquid with ammonia odor.
N,N-Dimethyl-N-ethanolamine has a role as a curing agent and a radical scavenger.
N,N-Dimethyl-N-ethanolamine is a tertiary amine and a member of ethanolamines.

CAS Number: 108-01-0
Molecular Formula: C4H11NO
Molecular Weight: 89.14
EINECS Number: 203-542-8

2-(Dimethylamino)ethanol, Deanol, N,N-Dimethylethanolamine, 108-01-0, Dimethylethanolamine, Dimethylaminoethanol, 2-DIMETHYLAMINOETHANOL, Norcholine, DMAE, Bimanol, Liparon, Varesal, N,N-Dimethylaminoethanol, Propamine A, DMEA, Ethanol, 2-(dimethylamino)-, (2-Hydroxyethyl)dimethylamine, Kalpur P, Dimethylmonoethanolamine, Dimethylaminoaethanol, N,N-Dimethyl-2-hydroxyethylamine, Amietol M 21, N,N-Dimethyl-2-aminoethanol, N-Dimethylaminoethanol, Texacat DME, N,N-Dimethyl ethanolamine, 2-(N,N-Dimethylamino)ethanol, Dimethyl(hydroxyethyl)amine, Dimethylaethanolamin, Dimethyl(2-hydroxyethyl)amine, 2-(Dimethylamino)-1-ethanol, N-(2-Hydroxyethyl)dimethylamine, Demanol, Demanyl, N,N-Dimethyl-N-(2-hydroxyethyl)amine, (Dimethylamino)ethanol, beta-Hydroxyethyldimethylamine, beta-Dimethylaminoethyl alcohol, 2-(Dimethylamino) ethanol, 2-Dwumetyloaminoetanolu, 2-Dimethylamino-ethanol, N,N-Dimethyl-N-(beta-hydroxyethyl)amine, NSC 2652, CCRIS 4802, N-(Dimethylamino)ethanol, Oristar dmae, HSDB 1329, N,N-Dimethyl(2-hydroxyethyl)amine, Tegoamin DMEA, EINECS 203-542-8, Dabco DMEA, UNII-2N6K9DRA24, 2-(dimethylamino)ethan-1-ol, Deanol [BAN], BRN 1209235, 2N6K9DRA24, DIMETHYL MEA, AI3-09209, CHEBI:271436, NSC-2652, N,N'-Dimethylethanolamine, 2-(dimethylamino)-ethanol, (CH3)2NCH2CH2OH, CHEMBL1135, .beta.-(Dimethylamino)ethanol, .beta.-Hydroxyethyldimethylamine, .beta.-Dimethylaminoethyl alcohol, DTXSID2020505, NSC2652, EC 203-542-8, Phosphatidyl-N-dimethylethanolamine, Deanol (BAN), MFCD00002846, n-(2-hydroxyethyl)-n,n-dimethylamine, N,N-DIMETHYLAMINOETHANOL (DMAE), NCGC00159413-02, Tonibral, N,N-Dimethyl-N-(.beta.-hydroxyethyl)amine, DEANOL (MART.), DEANOL [MART.], DTXCID00505, rexolin, CAS-108-01-0, Dimethylaethanolamin [German], Dimethylamino ethanol, Dimethylaminoaethanol [German], 2-Dwumetyloaminoetanolu [Polish], 2-Dimethylamino ethanol, UN2051, Ethanol, 2-dimethylamino-, N,N-Dimethyl-N-ethanolamine, 2-dimethylamino, N,N Dimethyl 2 hydroxyethylamine, Jeffcat DMEA, Dimethylethanoiamine, Toyocat -DMA, dimethyl ethanolamine, dimethyl-ethanolamine, DIMETHOL, Paresan (Salt/Mix), dimethyl ethanol amine, THANCAT DME, 2-dimethyamino-ethanol, n,n-dimethylethanolamin, Biocoline (Salt/Mix), beta-dimethylaminoethanol, N,N dimethylaminoethanol, DEANOL [WHO-DD], DEANOL [MI], N,N-dimethyl-ethanolamine, N,N-dimethylamino ethanol, N,N-dimethylethanol amine, N,N-dimethylethanol-amine, (n,n-dimethylamino)ethanol, 2-Hydroxyethyldimethylamine, 2-Dimethylaminoethanol [UN2051] [Corrosive], beta-(Dimethylamino)ethanol, beta -(dimethylamino)ethanol, DIMETHYL MEA [INCI], Dimethylaminoaethanol(german), N,N-Dimethylethanolamine (2-Dimethylaminoethanol), Choline chloride (Salt/Mix), Luridin chloride (Salt/Mix), beta -hydroxyethyldimethylamine, N,N-Dimethylethanolamine/DMEA, beta -dimethylaminoethyl alcohol, DMAE1549, 2-(N,N-dimethyl amino)ethanol, 2-(N,N-dimethylamino) ethanol, N-hydroxyethyl-N,N-dimethylamine, 2-(N,N-dimethyl amino) ethanol, beta -(dimethylamino)ethyl alcohol, 2-hydroxy-N,N-dimethylethanaminium, B-DIMETHYLAMINOETHYL ALCOHOL, WLN: Q2N1 & 1, 2-Dimethylaminoethanol, >=99.5%, BCP22017, CS-M3462, N,N-Dimethyl-beta-hydroxyethylamine, .beta.-(Dimethylamino)ethyl alcohol, N, N-Dimethyl(2-hydroxyethyl)amine, Tox21_113163, Tox21_201821, Tox21_302844, BDBM50060526, N,N-Dimethyl-beta -hydroxyethylamine, N,N-Dimethylaminoethanol, redistilled, 2-(DIMETHYLAMINO)ETHYL ALCOHOL, AKOS000118738, N,N-Dimethyl-.beta.-hydroxyethylamine, DB13352, N,N-DIMETHYLETHANOLAMINE [HSDB], RP10040, UN 2051, N, N-Dimethyl-N-(2-hydroxyethyl)amine, NCGC00159413-03, NCGC00256454-01, NCGC00259370-01, BP-13447, N,N-Dimethyl-N-(beta -hydroxyethyl)amine, N, N-Dimethyl-N-(beta -hydroxyethyl)amine, D0649, NS00001173, D07777, DIMETHYLAMINOETHANOL, (CORROSIVE LIQUID), 2-Dimethylaminoethanol [UN2051] [Corrosive

N,N-Dimethyl-N-ethanolamine is an organic compound with the formula (CH3)2NCH2CH2OH.
The synthesis of N,N-Dimethyl-N-ethanolamine by the ethylene oxide method is obtained by the ammonification of dimethylamine with ethylene oxide, which is distilled, refined and dehydrated.
N,N-Dimethyl-N-ethanolamine has been also used as an ingredient in skin care, and in cognitive function- and mood-enhancing products.

In addition, in vivo experiments showed that N,N-Dimethyl-N-ethanolamine is not methylated to choline and does not alter brain ACh levels.
Interestingly, in both acute and chronic seizure models in rats, a conjugate of N,N-Dimethyl-N-ethanolamine and valproate (DEVA) was shown to be more potent than valproate alone, potentially by facilitation of valproate transport via the blood brain barrier.
N,N-Dimethyl-N-ethanolamine is commonly referred to as 2-(dimethylamino)ethanol, dimethylaminoethanol (DMAE) or dimethylethanolamine (DMEA).

N,N-Dimethyl-N-ethanolamine holds tertiary amine and primary alcohol groups as functional groups.
N,N-Dimethyl-N-ethanolamine has been used in the treatment of attention deficit-hyperactivity disorder (ADHD), Alzheimer's disease, autism, and tardive dyskinesia.
However, results of several studies were inconclusive and a systematic review could not confirm the positive effects of N,N-Dimethyl-N-ethanolamine or other cholinergic compounds in patients with TD.

N,N-Dimethyl-N-ethanolamine is commonly referred to as 2-(dimethylamino)ethanol, dimethylaminoethanol (DMAE) or dimethylethanolamine (DMEA).
N,N-Dimethyl-N-ethanolamine holds tertiary amine and primary alcohol groups as functional groups.
N,N-Dimethyl-N-ethanolamine has been used in the treatment of attention deficit-hyperactivity disorder (ADHD), Alzheimer's disease, autism, and tardive dyskinesia.

N,N-Dimethyl-N-ethanolamine has been also used as an ingredient in skin care, and in cognitive function- and mood-enhancing products.
N,N-Dimethyl-N-ethanolamine and comes with molecular formula of C4H11NO and molecular weight of 89.13624.
N,N-Dimethyl-N-ethanolamine works as anti-depressive agent and is also used for treating movement disorders.

Available in colorless liquid form, it has amine odor with boiling point of 135 DEG C 758 MM HG, melting point of -59 DEG C, density/specific gravity of 0.8866 @ 20 DEG C/4 DEG C.
The chemical has miscible solubility with water, ether, acetone & benzene.
N,N-Dimethyl-N-ethanolamine is a tertiary amine that is ethanolamine having two N-methyl substituents.

N,N-Dimethyl-N-ethanolamine has a role as a curing agent and a radical scavenger.
N,N-Dimethyl-N-ethanolamine is a tertiary amine and a member of ethanolamines.
N,N-Dimethyl-N-ethanolamine is commonly referred to as 2-(dimethylamino)ethanol, dimethylaminoethanol (DMAE) or dimethylethanolamine (DMEA).

N,N-Dimethyl-N-ethanolamine holds tertiary amine and primary alcohol groups as functional groups.
N,N-Dimethyl-N-ethanolamine has been used in the treatment of attention deficit-hyperactivity disorder (ADHD), Alzheimer's disease, autism, and tardive dyskinesia.
N,N-Dimethyl-N-ethanolamine has been also used as an ingredient in skin care, and in cognitive function- and mood-enhancing products.

N,N-Dimethyl-N-ethanolamine is bifunctional, containing both a tertiary amine and primary alcohol functional groups.
N,N-Dimethyl-N-ethanolamine is a colorless viscous liquid.
N,N-Dimethyl-N-ethanolamine is used in skin care products for improving skin tone and also taken orally as a nootropic.

N,N-Dimethyl-N-ethanolamine is prepared by the ethoxylation of dimethylamine.
N,N-Dimethyl-N-ethanolamine, commonly known as Deanol, is a chemical compound with the molecular formula C4H11NO.
N,N-Dimethyl-N-ethanolamine is an organic compound that belongs to the class of alkanolamines.

N,N-Dimethyl-N-ethanolamine is a tertiary amine and has two methyl groups attached to the nitrogen atom, along with an ethyl group attached to the carbon adjacent to the nitrogen.
N,N-Dimethyl-N-ethanolamine is used as a curing agent for polyurethanes and epoxy resins.
N,N-Dimethyl-N-ethanolamine is a precursor to other chemicals, such as the nitrogen mustard 2-dimethylaminoethyl chloride.

The acrylate ester, N,N-Dimethyl-N-ethanolamine acrylate is used as a flocculating agent.
Related compounds are used in gas purification, e.g. removal of hydrogen sulfide from sour gas streams.
N,N-Dimethyl-N-ethanolamine is an organic chemical compound from the group of alkylated amino alcohols .

N,N-Dimethyl-N-ethanolamine is closely related to the neurotransmitter acetylcholine via choline (the trimethylethanolammonium cation).
N,N-Dimethyl-N-ethanolamine is an intermediate product of the chemical and pharmaceutical industries .
N,N-Dimethyl-N-ethanolamine is miscible with water, ethanol, benzene, ether and acetone.

N,N-Dimethyl-N-ethanolamine is a white powder providing 37% DMAE.
Animal tests show possible benefit for improving spatial memory and working memory.
N,N-Dimethyl-N-ethanolamine is produced industrially by reacting dimethylamine with ethylene oxide at temperatures of 125-160 ° C and pressures of 15-30 bar in the presence of catalytic amounts of water in liquid-cooled double-jacket tube reactors.

N,N-Dimethyl-N-ethanolamine is an organic compound with the formula (CH3)2NCH2CH2OH.
N,N-Dimethyl-N-ethanolamine is bifunctional, containing both a tertiary amine and primary alcohol functional groups.
N,N-Dimethyl-N-ethanolamine is a colorless viscous liquid.

N,N-Dimethyl-N-ethanolamine is used in skin care products for improving skin tone and also taken orally as a nootropic.
N,N-Dimethyl-N-ethanolamine is prepared by the ethoxylation of dimethylamine.
N,N-Dimethyl-N-ethanolamine is an amino alcohol.

N,N-Dimethyl-N-ethanolamine is the main product formed during the amination of ethylene glycol by dimethylamine on alumina supported copper in a continuous fixed-bed reactor.
N,N-Dimethyl-N-ethanolamine has been reported to be the putative precursor of acetylcholine.
N,N-Dimethyl-N-ethanolamine is effect as a skin-firming and anti-wrinkle agent has been studied.

Microwave spectrum of N,N-Dimethyl-N-ethanolamine has been investigated.
N,N-Dimethyl-N-ethanolamine is effect as an organic additive on deposition and anti-reflective properties of porous CaF2 has been studied.
Removal of the benzyl ester groups by transesterification with N,N-Dimethyl-N-ethanolamine from benzyl protected tripeptides has been reported.

N,N-Dimethyl-N-ethanolamine is a transparent, pale yellow liquid and primary alcohol that is used as a building block for the synthesis of cationic flocculants and ion exchange resins.
N,N-Dimethyl-N-ethanolamine is also used used as a chemical intermediate for pharmaceuticals, dyes, corrosion inhibitors, and emulsifiers and as an additive to boiler water, paint removers, and amino resins.
N,N-Dimethyl-N-ethanolamine is an organic compound with the formula (CH3)2NCH2CH2OH.

N,N-Dimethyl-N-ethanolamine is bifunctional, containing both a tertiary amine and primary alcohol functional groups.
N,N-Dimethyl-N-ethanolamine is a colorless viscous liquid.
N,N-Dimethyl-N-ethanolamine is used in skin care products.

N,N-Dimethyl-N-ethanolamine is prepared by the ethoxylation of dimethylamine.
N,N-Dimethyl-N-ethanolamine is a precursor to other chemicals, such as the nitrogen mustard 2-dimethylaminoethyl chloride.
The acrylate ester is used as a flocculating agent.Related compounds are used in gas purification, e.g. removal of hydrogen sulfide from sour gas streams.

N,N-Dimethyl-N-ethanolamine is a white powder providing 37% DMAE.
Deanol is commonly referred to as 2-(dimethylamino)ethanol, N,N-Dimethyl-N-ethanolamine or dimethylethanolamine (DMEA).
N,N-Dimethyl-N-ethanolamine holds tertiary amine and primary alcohol groups as functional groups.

N,N-Dimethyl-N-ethanolamine has been used in the treatment of attention deficithyperactivity disorder (ADHD), Alzheimer's disease, autism, and tardive dyskinesia.
N,N-Dimethyl-N-ethanolamine has been also used as an ingredient in skin care, and in cognitive function- and mood-enhancing products.
N,N-Dimethyl-N-ethanolamine appears as a clear colorless liquid with a fishlike odor.

N,N-Dimethyl-N-ethanolamine is a tertiary amine that is ethanolamine having two N-methyl substituents.
N,N-Dimethyl-N-ethanolamine has a role as a curing agent and a radical scavenger.
N,N-Dimethyl-N-ethanolamine is a tertiary amine and a member of ethanolamines.

N,N-Dimethyl-N-ethanolamine is a compound that many people believe can positively affect mood, enhance memory, and improve brain function.
N,N-Dimethyl-N-ethanolamine’s also thought to have benefits for aging skin.
While there aren’t many studies on N,N-Dimethyl-N-ethanolamine, advocates believe it may have benefits for several conditions, including: attention deficit hyperactivity disorder (ADHD).

N,N-Dimethyl-N-ethanolamine is naturally produced in the body.
N,N-Dimethyl-N-ethanolamine’s also found in fatty fish, such as salmon, sardines, and anchovies.
N,N-Dimethyl-N-ethanolamine is thought to work by increasing production of acetylcholine (Ach), a neurotransmitter that’s crucial for helping nerve cells send signals.

Ach helps regulate many functions controlled by the brain, including REM sleep, muscle contractions, and pain responses.
N,N-Dimethyl-N-ethanolamine may also help prevent the buildup of a substance called beta-amyloid in the brain.
Too much beta-amyloid has been linked to age-related decline and memory loss.

N,N-Dimethyl-N-ethanolamine’s impact on Ach production and beta-amyloid buildup may make it beneficial for brain health, especially as age.
N,N-Dimethyl-N-ethanolamine can be synthesized through the reaction of dimethylamine with ethylene oxide.
This reaction results in the formation of a tertiary amine, where two methyl groups are attached to the nitrogen atom and an ethyl group is attached to the adjacent carbon.

N,N-Dimethyl-N-ethanolamine finds various industrial applications due to its properties as a versatile amine.
N,N-Dimethyl-N-ethanolamine is commonly used as a catalyst or a reactant in chemical reactions, particularly in the synthesis of pharmaceuticals, pesticides, and corrosion inhibitors.
In cosmetics and personal care products, N,N-Dimethyl-N-ethanolamine is utilized as an ingredient in formulations such as skin care products, hair care products, and toiletries.

N,N-Dimethyl-N-ethanolamine can act as a pH adjuster, emulsifier, or conditioning agent in these formulations.
N,N-Dimethyl-N-ethanolamine has gained attention in the field of nootropics and cognitive enhancement.
Some individuals use Deanol-containing supplements for its potential to improve cognitive function, memory, and focus.

However, scientific evidence supporting these claims is limited, and more research is needed to determine its effectiveness and safety for cognitive enhancement purposes.
N,N-Dimethyl-N-ethanolamine is regulated by various regulatory bodies, including the U.S. Food and Drug Administration (FDA) and the European Chemicals Agency (ECHA).
N,N-Dimethyl-N-ethanolamine is important to adhere to regulations and guidelines regarding its use in different applications to ensure safety and compliance.

While Deanol is generally regarded as safe when used in accordance with regulations and guidelines, it is essential to handle it with care due to its potential hazards.
Proper safety precautions, such as wearing appropriate personal protective equipment and following handling instructions, should be observed when working with this compound.
Research on N,N-Dimethyl-N-ethanolamine continues to explore its potential applications and properties. Studies may focus on its chemical reactivity, biological effects, and
potential uses in various industries, contributing to ongoing advancements in science and technology.

N,N-Dimethyl-N-ethanolamine has previously been investigated as a stimulant and treatment for several neurological diseases, including tardive dyskinesia (TD), Alzheimer’s disease (AD) and senile dementia.
First, application of N,N-Dimethyl-N-ethanolamine to human healthy volunteers dates back to the 1960s when N,N-Dimethyl-N-ethanolamine was reported to exert stimulating effects comparable to amphetamine.
Murphree et al. (1960) described improved concentration, increased muscle tone and changed sleeping habits in healthy males (21–26 years) with an intake of 10–20 mg N,N-

Dimethyl-N-ethanolamine (or Deanol) daily for 2–3 weeks compared to a placebo group.
In later studies, N,N-Dimethyl-N-ethanolamine was hypothesized as an acetylcholine (ACh) precursor and therefore tested in diseases that are considered to be linked to the cholinergic system.
N,N-Dimethyl-N-ethanolamine is a tertiary amine that is ethanolamine having two N-methyl substituents.

Melting point: −70 °C(lit.)
Boiling point: 134-136 °C(lit.)
Density: 0.886 g/mL at 20 °C(lit.)
vapor density: 3.03 (vs air)
vapor pressure: 100 mm Hg ( 55 °C)
refractive index: n20/D 1.4294(lit.)
Flash point: 105 °F
storage temp.: Store below +30°C.
solubility: alcohol: miscible(lit.)
form: Liquid
pka: pK1:9.26(+1) (25°C)
color: Clear colorless to pale yellow
Odor: Amine like
PH Range: 10.5 - 11.0 at 100 g/l at 20 °C
PH: 10.5-11 (100g/l, H2O, 20℃)
explosive limit 1.4-12.2%(V)
Water Solubility: miscible
FreezingPoint: -59.0℃
Sensitive: Hygroscopic
Merck: 14,2843
BRN: 1209235
Stability: Stable. Flammable. Incompatible with oxidizing agents, copper, copper alloys, zinc, acids, galvanised iron. Hygroscopic.
InChIKey: UEEJHVSXFDXPFK-UHFFFAOYSA-N
LogP: -0.55 at 23℃

N,N-Dimethyl-N-ethanolamine is an aminoalcohol.
N,N-Dimethyl-N-ethanolamine has been submitted to the National Cancer Institute (NCI) for testing and evaluation and the Cancer Chemotherapy National Service Center (NSC) number is 2652.
N,N-Dimethyl-N-ethanolamine is sometimes included as an ingredient in combination products, alongside other compounds purported to have cognitive-enhancing effects.

These products may contain vitamins, minerals, antioxidants, or herbal extracts, aiming to synergistically improve cognitive function.
However, the efficacy of such combinations should be evaluated through rigorous scientific research.
N,N-Dimethyl-N-ethanolamine-containing products marketed for cognitive enhancement often attract public interest, particularly among individuals seeking ways to support brain health and cognitive performance.

N,N-Dimethyl-N-ethanolamine is important for consumers to critically evaluate marketing claims and seek evidence-based information from reliable sources when considering the use of these products.
Regulatory agencies oversee the safety and labeling of N,N-Dimethyl-N-ethanolamine-containing products to ensure compliance with regulations.
Manufacturers are responsible for conducting safety assessments, adhering to labeling requirements, and providing accurate information to consumers.

Regulatory oversight helps safeguard public health and prevent misleading claims or unsafe practices in the marketplace.
Educational resources, such as scientific literature, reputable websites, and healthcare professionals, can provide valuable information about N,N-Dimethyl-N-ethanolamine and its potential effects.
Consumers and healthcare providers can use these resources to make informed decisions about its use, weighing potential benefits against risks and considering individual health
needs and preferences.

N,N-Dimethyl-N-ethanolamine belongs to the ontological category of tertiary amine in the ChEBI Ontology tree.
The United Nations designated GHS hazard class pictogram is Flammable;Corrosive;Irritant, and the GHS signal word is DangerThe storage condition is described as Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
N,N-Dimethyl-N-ethanolamine use and application categories indicated by third-party sources: Fire Hazards -> Corrosives, Flammable - 2nd degree.

However, this does not mean N,N-Dimethyl-N-ethanolamine can be used or applied in the same or a similar way.
N,N-Dimethyl-N-ethanolamine has been studied for its potential biological effects, including its interaction with neurotransmitter systems in the brain.
Some research suggests that it may modulate levels of acetylcholine, a neurotransmitter involved in memory and cognition.

However, the exact mechanisms of action and their significance in cognitive function are still not fully understood.
Upon ingestion, N,N-Dimethyl-N-ethanolamine is metabolized in the body.
N,N-Dimethyl-N-ethanolamine undergoes processes such as oxidation and conjugation, leading to the formation of various metabolites.

Understanding its metabolic pathways is important for assessing its safety and potential health effects.
While N,N-Dimethyl-N-ethanolamine is generally considered safe when used appropriately, excessive intake or exposure may lead to adverse effects.
Some reported side effects include gastrointestinal disturbances, such as nausea and stomach upset.

Additionally, there have been concerns about potential liver toxicity associated with high doses, although more research is needed to confirm these effects.
N,N-Dimethyl-N-ethanolamine may interact with other substances, medications, or supplements.
Individuals taking medications or supplements should consult healthcare professionals before using N,N-Dimethyl-N-ethanolamine-containing products to avoid potential interactions or adverse effects.

N,N-Dimethyl-N-ethanolamine is available in various formulations, including oral supplements, topical creams, and liquid solutions.
The concentration and form of N,N-Dimethyl-N-ethanolamine in these products may vary, influencing its absorption, bioavailability, and effectiveness.
Despite its potential benefits, research on Deanol faces challenges, including variability in study designs, inconsistent findings, and a lack of standardized protocols.

Addressing these challenges is essential for advancing scientific understanding and establishing evidence-based recommendations regarding its use.
Regulatory agencies evaluate the safety and efficacy of N,N-Dimethyl-N-ethanolamine-containing products based on scientific evidence.
Compliance with regulatory requirements ensures that N,N-Dimethyl-N-ethanolamine meet quality standards and are safe for consumer use.

Consumers should be aware of the limitations of available evidence and exercise caution when using Deanol-containing products, particularly those marketed for cognitive enhancement.
Consulting healthcare professionals and reputable sources can help individuals make informed decisions about its use.
In cosmetics, N,N-Dimethyl-N-ethanolamine is often incorporated into formulations targeting skin care and hair care products.

N,N-Dimethyl-N-ethanolamine can act as a pH adjuster, emulsifier, or humectant, contributing to the stability, texture, and moisturizing properties of these products.
Some formulations may claim to have firming or toning effects on the skin due to N,N-Dimethyl-N-ethanolamine's potential to enhance skin elasticity.
While the exact mechanisms underlying N,N-Dimethyl-N-ethanolamine's purported cognitive-enhancing effects are not fully understood, some hypotheses suggest that it may influence cholinergic neurotransmission.

Cholinergic pathways play a crucial role in memory, attention, and learning processes.
N,N-Dimethyl-N-ethanolamine's interaction with these pathways may modulate neurotransmitter levels and neuronal activity, affecting cognitive function.
Ongoing research continues to explore N,N-Dimethyl-N-ethanolamine's potential therapeutic applications and mechanisms of action.

Studies may investigate its effects on neuroplasticity, neuroprotection, and neurotransmitter systems to elucidate its role in cognitive function and neurological disorders.
Additionally, clinical trials assessing N,N-Dimethyl-N-ethanolamine's efficacy and safety in specific populations, such as older adults or individuals with cognitive impairments, are warranted.
Amines are chemical bases.

They neutralize acids to form salts plus water.
These acid-base reactions are exothermic.
The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base.

Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
N,N-Dimethyl-N-ethanolamine may react vigorously with oxidizing materials.

N,N-Dimethyl-N-ethanolamine is used as a corrosion inhibitor; pharmaceutical intermediate; in making dyestuffs, textiles, pharmaceuticals; emulsifiers in paints and coatings.
Also, N,N-Dimethyl-N-ethanolamine has been used as a medication in the treatment ofbehavioral problems of children.
When administered orally, N,N-Dimethyl-N-ethanolamine acetamidobenzoate (the therapeutic salt formulation) has been shown to cross the blood-brain barrier (HSDB 1988).

Two other studies have examined the pharmacokinetics of dimethylaminoethanol in rats and healthy adults.
N,N-Dimethyl-N-ethanolamine is a chemical that can be converted into choline.
Choline is involved in a series of reactions that form acetylcholine, a chemical that is found in the brain and other areas of the body.

N,N-Dimethyl-N-ethanolamine is a "neurotransmitter" that helps nerve cells communicate.
N,N-Dimethyl-N-ethanolamine is used for attention deficit-hyperactivity disorder (ADHD), Alzheimer disease, autism, and other conditions, but there is no good scientific evidence to support these uses.

The exact mass of the compound N,N-Dimethyl-N-ethanolamine is 89.0841 and the complexity rating of the compound is unknown.
The solubility of this chemical has been described as greater than or equal to 100 mg/ml at 73° f (ntp, 1992)11.22 mmiscible with watermiscible with alcohol, ethermiscible with acetone, benzene1000 mg/mlsolubility in water: miscible.

Uses:
N,N-Dimethyl-N-ethanolamine is used as corrosion inhibitor, anti-scaling agent, paint additive, coating additive and solids separation agent.
N,N-Dimethyl-N-ethanolamine is used for the manufacture of: fabricated metal products, machinery and vehicles, mineral products (e.g. plasters, cement) and metals.
Other release to the environment of N,N-Dimethyl-N-ethanolamine is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

N,N-Dimethyl-N-ethanolamine is used in the following products: polymers, coating products, fillers, putties, plasters, modelling clay and inks and toners.
Release to the environment of N,N-Dimethyl-N-ethanolamine can occur from industrial use: formulation of mixtures, manufacturing of the substance, formulation in materials, in the production of articles and as an intermediate step in further manufacturing of another substance (use of intermediates).
N,N-Dimethyl-N-ethanolamine is used in the following products: polymers, coating products and paper chemicals and dyes.

N,N-Dimethyl-N-ethanolamine has an industrial use resulting in manufacture of another substance (use of intermediates).
N,N-Dimethyl-N-ethanolamine is used in the following areas: formulation of mixtures and/or re-packaging and building & construction work.
N,N-Dimethyl-N-ethanolamine is used for the manufacture of: chemicals, pulp, paper and paper products, fabricated metal products, machinery and vehicles and plastic products.

Release to the environment of N,N-Dimethyl-N-ethanolamine can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), in the production of articles, formulation in materials, for thermoplastic manufacture and as processing aid.
N,N-Dimethyl-N-ethanolamine is a precursor to other chemicals, such as the nitrogen mustard 2-dimethylaminoethyl chloride.
N,N-Dimethyl-N-ethanolamine is used in gas purification.

In certain chemical reactions, N,N-Dimethyl-N-ethanolamine can function as a catalyst, accelerating the rate of reaction without being consumed in the process.
N,N-Dimethyl-N-ethanolamine facilitates the conversion of reactants into desired products and may enhance reaction efficiency in various industrial processes.
N,N-Dimethyl-N-ethanolamine is incorporated into cosmetic formulations, including skin care products, hair care products, and toiletries.

N,N-Dimethyl-N-ethanolamine can serve multiple functions in these formulations, such as adjusting pH, emulsifying ingredients, and providing moisturizing or conditioning effects.
N,N-Dimethyl-N-ethanolamine is a common ingredient in some dietary supplements marketed for cognitive enhancement or brain health.
These supplements often claim to support memory, focus, and mental clarity, although scientific evidence supporting these claims is limited and controversial.

N,N-Dimethyl-N-ethanolamine is studied for its potential therapeutic effects in various health conditions, including neurodegenerative disorders and cognitive impairments.
Research explores its mechanisms of action, pharmacokinetics, and potential benefits as a treatment adjunct or therapeutic agent.
N,N-Dimethyl-N-ethanolamine can be used as an additive in polymer formulations to impart desired properties, such as enhanced flexibility, adhesion, or resistance to degradation.

N,N-Dimethyl-N-ethanolamine may improve the performance of polymeric materials in applications ranging from adhesives and coatings to plastics and composites.
N,N-Dimethyl-N-ethanolamine serves as a solvent or co-solvent, facilitating the dissolution of substances and aiding in the production of formulations or chemical mixtures.
N,N-Dimethyl-N-ethanolamine is solvent properties make it valuable in applications such as cleaning, degreasing, and extraction processes.

N,N-Dimethyl-N-ethanolamine can act as a surfactant, lowering the surface tension between two substances and promoting their mixing or dispersion.
N,N-Dimethyl-N-ethanolamine finds application in formulations such as detergents, emulsifiers, foaming agents, and dispersants in various industrial and household products.
N,N-Dimethyl-N-ethanolamine may be used as a dyeing assistant, leveling agent, or softening agent to improve the processing and quality of textile materials.

N,N-Dimethyl-N-ethanolamine can enhance dye uptake, uniformity of coloration, and fabric handle, contributing to the production of high-quality textiles.
N,N-Dimethyl-N-ethanolamine is utilized in gas treatment processes, particularly in the removal of acidic gases such as hydrogen sulfide (H2S) and carbon dioxide (CO2) from natural gas and biogas streams.
N,N-Dimethyl-N-ethanolamine can react with acidic components to form stable salts or complexes, thereby purifying the gas for various industrial applications.

In the printing industry, N,N-Dimethyl-N-ethanolamine may be incorporated into ink formulations as a solvent or additive to enhance print quality, adhesion, and drying characteristics.
N,N-Dimethyl-N-ethanolamine can help optimize ink performance and improve the printing process in applications such as offset printing, flexography, and gravure printing.
N,N-Dimethyl-N-ethanolamine is sometimes added to metalworking fluids, such as cutting oils and coolants, to improve lubricity, thermal stability, and corrosion protection during machining, grinding, and metal forming operations.

N,N-Dimethyl-N-ethanolamine enhances tool life, surface finish, and overall machining efficiency in metalworking processes.
In photographic applications, Deanol may be used in the formulation of developers, fixing agents, and other processing chemicals.
N,N-Dimethyl-N-ethanolamine plays a role in the development and stabilization of photographic images, contributing to the production of high-quality prints in traditional and digital photography.

N,N-Dimethyl-N-ethanolamine can serve as a catalyst or blowing agent in the production of polyurethane foams.
N,N-Dimethyl-N-ethanolamine promotes the polymerization reaction and facilitates the formation of cellular structures, leading to the production of flexible or rigid foams with desired properties such as density, resilience, and thermal insulation.
In water treatment and detergent formulations, N,N-Dimethyl-N-ethanolamine may act as a sequestering agent or chelating agent, binding to metal ions and preventing their precipitation or interference with chemical processes.

N,N-Dimethyl-N-ethanolamine helps improve water quality, prevent scale formation, and enhance the performance of cleaning products.
N,N-Dimethyl-N-ethanolamine is used in the synthesis of synthetic resins, including epoxy resins, polyurethane resins, and acrylic resins.
N,N-Dimethyl-N-ethanolamine contributes to the polymerization process, crosslinking reactions, or resin modification, leading to the production of resins with specific properties suitable for coatings, adhesives, and composite materials.

In coatings and paint formulations, N,N-Dimethyl-N-ethanolamine may be employed as a coalescing agent or viscosity modifier in waterborne systems.
N,N-Dimethyl-N-ethanolamine aids in film formation, film integrity, and flow properties, allowing for the production of environmentally friendly coatings with excellent performance and durability.
N,N-Dimethyl-N-ethanolamine can be utilized in wood preservation treatments to enhance the resistance of timber and wood products against decay, fungi, and insects.

N,N-Dimethyl-N-ethanolamine penetrates wood fibers, inhibits microbial growth, and prolongs the service life of wood structures in outdoor or humid environments.
N,N-Dimethyl-N-ethanolamine may have additional applications in diverse industries, including adhesives, sealants, lubricants, agricultural chemicals, and electronic materials.
N,N-Dimethyl-N-ethanolamine is multifunctional properties and compatibility with various substrates make it valuable in addressing specific performance requirements across different industrial sectors.

N,N-Dimethyl-N-ethanolamine is bitartrate salt is sold as a dietary supplement.
N,N-Dimethyl-N-ethanolamine has been also used as an ingredient in skin care.
N,N-Dimethyl-N-ethanolamine is used in Mood-enhancing products.

N,N-Dimethyl-N-ethanolamine serves as a precursor or intermediate in the synthesis of various chemicals, including pharmaceuticals, agrochemicals, and specialty chemicals.
N,N-Dimethyl-N-ethanolamine is utilized in organic synthesis reactions due to its amine functionality, contributing to the formation of complex molecules.
N,N-Dimethyl-N-ethanolamine is employed as a component in corrosion inhibitor formulations, particularly in industries where metal corrosion poses a significant challenge.

N,N-Dimethyl-N-ethanolamine helps mitigate corrosion by forming a protective layer on metal surfaces, thereby extending the lifespan of equipment and infrastructure.
N,N-Dimethyl-N-ethanolamine is also used as an intermediate for active pharmaceutical ingredients and dyes.
N,N-Dimethyl-N-ethanolamine serves as a curing agent for polyurethanes and epoxy resins.

Further, N,N-Dimethyl-N-ethanolamine is used as an additive to boiler water.
In addition to this, N,N-Dimethyl-N-ethanolamine is used therapeutically as a CNS stimulant.
MEA (DMAE) is also known as N,N-Dimethyl-N-ethanolamine.

Studies indicate skin-firming properties, and an ability to reduce the appearance of fine lines and wrinkles as well as dark circles under the eyes.
N,N-Dimethyl-N-ethanolamine is considered anti-aging, and antiinflammatory, and has exhibited free-radical scavenging activity.
N,N-Dimethyl-N-ethanolamine may be employed as a ligand in the copper-catalyzed amination of aryl bromides and iodides.

N,N-Dimethyl-N-ethanolamine is used as a chemical intermediate for antihistamines and local anesthetics; as a catalyst for curing epoxy resins and polyurethanes; and as a pH control agent for boiler water treatment.
However, N,N-Dimethyl-N-ethanolamine in the salt form, (i.e. dimethylaminoethanol acetamidobenzoate) is primarily utilized therapeutically as an antidepressant.
N,N-Dimethyl-N-ethanolamine is used as an aid for dispersing color pigments in water-based paints .

Furthermore, N,N-Dimethyl-N-ethanolamine is required as an intermediate product or starting material for the production of dyes , emulsifiers , corrosion inhibitors , textile auxiliaries, cosmetics and pharmaceuticals .
N,N-Dimethyl-N-ethanolamine is said to have a variety of positive effects, including nootropic effects , but there is a lack of clear evidence for this.
One author reports increased lucid dreams after using N,N-Dimethyl-N-ethanolamine.

N,N-Dimethyl-N-ethanolamine may be used as a ligand in the copper-catalyzed amination of aryl bromides and iodides.
N,N-Dimethyl-N-ethanolamine is used in the following products: laboratory chemicals, coating products, polymers, fillers, putties, plasters, modelling clay, lubricants and greases and adhesives and sealants.
N,N-Dimethyl-N-ethanolamine is used in the following areas: building & construction work, offshore mining and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.

Health Hazard:
N,N-Dimethyl-N-ethanolamine is classified as a mild skin irritant and a severe eye irritant.
Doses as high as 1200 mg daily produce no serious side effects and a single dose of 2500 mg taken in a suicide attempt had no adverse effects.
Inhalation of the vapor or mist can cause irritation to the upper respiratory tract.

Asthmatic symptoms have been reported.
Extremely irritating; may cause permanent eye injury. Corrosive; will cause severe skin damage with burns and blistering.
Ingestion may cause damage to the mucous membranes and gastrointestinal tract.

Safety Profile:
N,N-Dimethyl-N-ethanolamine causes increased blood pressure.
N,N-Dimethyl-N-ethanolamine can cause stomach upset, headaches & muscle tension.
Can lead to drowsiness, confusion and irritability.

Moderately toxic by ingestion, inhalation, skin contact, intraperitoneal, and subcutaneous routes.
A skin and severe eye irritant.
Used medically as a central nervous system stimulant.

Flammable liquid when exposed to heat or flame; can react vigorously with oxidzing materials.
Ignites spontaneously in contact with cellulose nitrate of high surface area.
To fight fire, use alcohol foam, foam, CO2, dry chemical.

N,N-DIMETHYL-PARA-TOLUIDINE
N,N-Dimethyl-para-toluidine N,N-dimethyl-para-toluidine is used as a polymerization accelerator in the manufacture of bone cements and dental materials, in industrial glues, and as an intermediate in dye and pesticide synthesis. Thus, there is potential for human exposure to N,N-dimethyl-para-toluidine, an aromatic amine with a structural alert for potential DNA reactivity. The National Toxicology Program (NTP) is evaluating the toxicity and carcinogenicity of N,N-dimethyl-para-toluidine in male and female Fischer 344 rats and B6C3F1 mice. To aid in the design and interpretation of those studies, we have investigated the excretion and tissue distribution of oral and intravenous (IV) doses of radiolabeled N,N-dimethyl-para-toluidine in these strains of rodents. A single low (2.5 mg/kg), mid (25 mg/kg) or high (250 mg/kg) dose of carbon-14 labeled N,N-dimethyl-para-toluidine was administered. Excreta collected for up to 72 hr after dosing and tissues collected at sacrifice were analyzed for total radioactivity. Early studies were terminated at 72 hr. After a low IV dose to male rats ~100% of the dose was excreted and <2% was recovered in tissues at 72 hr. The high oral dose was acutely toxic to male mice. The same oral dose was not overtly toxic to male rats, and by 72 hr 86% of the dose was excreted and 2% remained in tissues. Subsequent studies were terminated at 24 hr to better understand the tissue distribution of radioactivity at earlier time points, which are more relevant to the interpretation of repeated dose toxicity studies. After the high oral dose to male rats ~18% of the dose was recovered in tissues and ~72% was excreted by 24 hr. In contrast, at the low and mid doses most of the radioactivity (~83-100%) was excreted by 24 hr and <5% remained in tissues. In summary, N,N-dimethyl-para-toluidine derived radioactivity was rapidly excreted by rats and mice after a single oral or IV dose and no striking sex differences in N,N-dimethyl-para-toluidine disposition were observed within a species. However, dose dependent differences in toxicity and disposition were observed. These data will be used to aid in the interpretation of safety/toxicity studies of N,N-dimethyl-para-toluidine conducted by the NTP. Product Information of N,N-Dimethyl-para-toluidine CAS number 99-97-8 EC index number 612-056-00-9 EC number 202-805-4 Hill Formula C₉H₁₃N Chemical formula 4-(CH₃)C₆H₄N(CH₃)₂ Molar Mass 135.21 g/mol HS Code 2921 43 00 The metabolism of orally administered N,N-dimethyl-p-toluidine (DMPT) in male F344 rats was investigated. The rat urinary metabolite profile was determined by analytical reverse-phase high performance liquid chromatography (HPLC). Four radiolabeled peaks were observed, isolated, and purified by solid-phase extraction (SPE) and preparative HPLC methods. The 4 peaks were identified as p-(N-acetylhydroxyamino)hippuric acid (M1), N,N-dimethyl-para-toluidine N-oxide (M2), N-methyl-p-toluidine (M3), and parent N,N-dimethyl-para-toluidine. Metabolites M1 and M2 were identified by spectrometric and spectroscopic methods, including mass fragmentation pattern identification from both liquid chromatography/mass spectrometry and gas chromatography/mass spectrometry, and from chemical analysis of nuclear magnetic resonance spectra. Structural confirmation of metabolite M2 was accomplished by comparison with a synthetic standard. Peaks M3 and the peak suspected to be N,N-dimethyl-para-toluidine were identified by comparison of their HPLC retention times and mass fragmentation patterns with authentic standards of N-methyl-p-toluidine and N,N-dimethyl-para-toluidine, respectively. N,N-dimethyl-para-toluidine metabolism is similar to that reported for N,N-dimethylaniline. IDENTIFICATION of N,N-Dimethyl-para-toluidine: N,N-dimethyl-para-toluidine is a colorless liquid to brown oil. It has an aromatic odor. It does not dissolve in water. USE of N,N-Dimethyl-para-toluidine: N,N-dimethyl-para-toluidine is used to make acrylic resins and denture materials. It is used in the cement in most hip and bone replacements. N,N-dimethyl-para-toluidine is also used to make dyes and pesticides, industrial glues, and artificial fingernail preparations. EXPOSURE of N,N-Dimethyl-para-toluidine: There is potential for widespread human exposure because of its use in dental materials and bone cements. If released to the environment, N,N-dimethyl-para-toluidine may be broken down rapidly in air. It travels through soil. It may volatilize from moist soil and water surfaces. However, it will exist partially as an ion. Ions do not volatilize. This type of ion is not likely to leach. It is not known if this chemical is biodegradable in soil or water. There is a potential for buildup in aquatic organisms. RISK: Some people with dental materials and bone cements containing N,N-dimethyl-para-toluidine have developed allergic reactions. In studies of rats and mice given N,N-dimethyl-para-toluidine by mouth 5 days per week for 3 months, early deaths occurred at doses equal to or greater than 125 mg/kg body weight. In surviving mice and rats, adverse effects were found in the blood, nose, lung and liver. Cancer was found in studies of rats and mice given N,N-dimethyl-para-toluidine by mouth 5 days per week for two years. In rats, liver and nose cancers were found. In mice, liver, lung and forestomach cancers were found. The California Environmental Protection Agency's Office of Environmental Health Hazard Assessment announced in April 2014 that it intends to list N,N-dimethyl-para-toluidine as known to the State to cause cancer. The U.S. EPA IRIS program, the International Agency for Research on Cancer, and the U.S. National Toxicology Program Twelfth Report on Carcinogens have not assessed the potential of N,N-dimethyl-para-toluidine to cause cancer in humans. N,N-dimethyl-para-toluidine is an accelerator in the redox initiator-accelerator system used commercially to cure methyl methacrylate monomers. Polymerization is rarely complete. N,N-dimethyl-para-toluidine is a high-production volume chemical with potential for widespread human exposure through its use in dental materials and bone cements. N,N-dimethyl-para-toluidine has been used in the preparation of acrylic denture materials for the past 50 years. It is used as the accelerator for the cement in most of the hip and bone replacements to activate the polymerization reaction at concentrations ranging from 0.7% to 2.6% . N,N-dimethyl-para-toluidine is found in industrial glues and artificial fingernail preparations and is used as an intermediate in dye and pesticide synthesis. It has a shorter setting time (11.5 minutes) than some alternative accelerators. Acryl resins used in dental practice are blends of poly(methyl methacrylated) particles and methyl methacrylate monomer, or copolymers of methyl methacrylate with styrene or other acrylic monomers. This blend is a slurry of high viscosity that is hardened by the free radical polymerization of the monomeric components. The hardening process is initiated by the decomposition of a small quantity of organic peroxides (1% to 3%; usually benzoyl peroxide) activated by the redox reaction with the tertiary amine. The tertiary amine, most often N,N-dimethyl-para-toluidine, is the ingredient that induces the reaction giving rise to free radicals capable of initiating polymerization of the acrylic monomers. Polymerization is rarely complete. Five commercially available bone cements were analysed by high-performance liquid chromatography for detecting the residual content of an accelerator, the amine N,N-dimethyl-p-toluidine (N,N-dimethyl-para-toluidine), after curing. It was found that the concentration of N,N-dimethyl-para-toluidine in aqueous extracts decreases with time, being almost absent 7 days after curing. Differences were noticed among the cements; residual N,N-dimethyl-para-toluidine is higher in cements prepared with higher content of the amine. It is verified that N,N-dimethyl-para-toluidine's toxic effect on cell cultures is dose-related; a delay in the cell replication cycle is induced in vitro. Damage is reversible, thus justifying the low bone cement toxicity that is clinically ascertained. The use of solid phase extraction (SPE) and high performance liquid chromatography (HPLC) for the analysis of toxic components eluted from methyl-methacrylate polymer (pMMA) dental materials was described. Two pMMA composite resins, Yunifast and Acron, were analyzed. Yunifast was polymerized at room temperature, and Acron at 100 degrees-C. Each sample was then placed in equine serum at room temperature, and serum was replaced daily. The serum extract was subjected to SPE and HPLC, for methyl-methacrylate, N,N-dimethyl-p-toluidine (N,N-dimethyl-para-toluidine), and benzoylperoxide (BPO) (initiator and stimulator for the polymerization) analysis. Results showed that the MMA and N,N-dimethyl-para-toluidine eluted was in the order of 10 to 100 parts per million. Almost negligible amounts of BPO and benzoic-acid were also eluted. A greater amount of these compounds was eluted from Yunifast, a more pliant material. N,N-dimethyl-para-toluidine showed greater elution than MMA. The hydrophilic portion of Yunifast was more cytotoxic than the hydrophobic portion, and contained BA and p-toluidine as major and minor components. The /study/ conclude that the rigidity of the material is critical to the extractable quantity, and recommend that both Yunifast and Acron be immersed in hot water before use in order to remove hydrophilic toxic compounds from these pMMA dental materials. The National Occupational Exposure Survey, which was conducted by the National Institute for Occupational Safety and Health (NIOSH) between 1981 and 1983, estimated that 62,720 workers were potentially exposed to N,N-dimethyl-para-toluidine in the workplace (NIOSH, 1990). There is potential for widespread human exposure to N,N-dimethyl-para-toluidine in occupational settings where bone cements, dental prostheses, industrial glues, and artificial fingernails are manufactured or used. Exposure to N,N-dimethyl-para-toluidine may be a concern because of the possible release of unreacted chemicals from polymeric composites. IDENTIFICATION AND USE of N,N-Dimethyl-para-toluidine: N,N-dimethyl-para-toluidine is a clear to yellow liquid with an aromatic odor; insoluble in water. N,N-dimethyl-para-toluidine is an accelerator in the redox initiator-accelerator system used commercially to cure methyl methacrylate monomers. It is a high-production volume chemical with potential for widespread human exposure through its use in dental materials and bone cements. N,N-dimethyl-para-toluidine has been used in the preparation of acrylic denture materials for the past 50 years. It is used as the accelerator for the cement in most of the hip and bone replacements to activate the polymerization reaction. N,N-dimethyl-para-toluidine is found in industrial glues and artificial fingernail preparations and is used as an intermediate in dye and pesticide synthesis. HUMAN EXPOSURE AND TOXICITY of N,N-Dimethyl-para-toluidine: Toxic by skin absorption and inhalation. Short-term exposure effects are mostly hematotoxic (methemoglobinemia causing cyanosis, brain damage and renal insufficiency) and may be delayed. Exposure to high concentrations may lead to death. An acute cyanotic episode due to methemoglobinemia occurred in a 16-month old girl following the ingestion of N,N-dimethyl-para-toluidine (6 mg/kg of body weight ) used in the production of artificial fingernails. Administration of methylene blue was effective in the reversal of the methemoglobinemia. In vitro studies suggest that the activity of the compound was probably due to its biochemical transformation to the toxic metabolite p-methylphenylhydroxylamine. There is potential for widespread human exposure to N,N-dimethyl-para-toluidine in occupational settings where bone cements, dental prostheses, industrial glues, and artificial fingernails are manufactured or used. Exposure to N,N-dimethyl-para-toluidine may be a concern because of the possible release of unreacted chemicals from polymeric composites. "Sniffing" glue is one possible means of exposure to N,N-dimethyl-para-toluidine. Contact allergy to N,N-dimethyl-para-toluidine was reported in 3 cases among 22 patients with the burning mouth syndrome who wore complete or partial dentures. ANIMAL STUDIES of N,N-Dimethyl-para-toluidine: Under the conditions of the NTP 2-year oral gavage studies, there was clear evidence of carcinogenic activity of N,N-dimethyl-para-toluidine in rats based on increased incidences of hepatocellular carcinoma, and hepatocellular adenoma or carcinoma (combined) in male and female rats, and increased incidences of nasal cavity neoplasms (primarily nasal cavity transitional epithelium adenoma) in male rats. There was clear evidence of carcinogenic activity of N,N-dimethyl-para-toluidine in mice based on increased incidences of hepatocellular adenoma (multiple), hepatocellular carcinoma, and hepatoblastoma in male and female mice, and increased incidences of alveolar/ bronchiolar neoplasms (primarily adenoma)in female mice. Administration of N,N-dimethyl-para-toluidine resulted in increased incidences of nonneoplastic lesions of the liver and nasal cavity in male and female rats and mice; the kidney in male and female rats; the spleen and bone marrow in male and female rats and female mice; the lung in male and female mice; the forestomach in male rats and female mice; the mesenteric lymph node in male rats and female mice; and the olfactory lobe in male and female mice. N,N-dimethyl-para-toluidine also caused hematologic toxicity and increases in methemoglobin levels in male and female rats and mice (as measured at 3 months). N,N-dimethyl-para-toluidine was tested in two independent bacterial gene mutation studies; both studies gave negative results in S. typhimurium or E. coli tester strains, with and without exogenous metabolic activation. No significant increases in the frequencies of micronucleated erythrocytes were observed in peripheral blood of male or female mice treated with N,N-dimethyl-para-toluidine by gavage for 3 months. Furthermore, no increases in micronucleated reticulocytes were observed in male mice treated with N,N-dimethyl-para-toluidine for 4 days. Results of DNA damage (comet) studies yielded mixed results. No increases in DNA damage (measured as percent tail DNA) were seen in liver cells or blood leukocytes of male mice administered N,N-dimethyl-para-toluidine by gavage once daily for 4 days. However, a small but significant increase in DNA damage was seen in liver cells of male rats administered 60 mg/kg N,N-dimethyl-para-toluidine once daily for 4 days. It was also tested for structural and numerical chromosome aberrations in hamster V79 cells (micronucleus test, matched with an immunofluorescent staining for kinetochore proteins), and in vivo DNA damage in mouse and rat liver (alkaline DNA elution test). The results essentially indicate that the chemical is a chromosome damaging agent. In two in vivo alkaline elution assays, Sprague-dawley rats were administered N,N-dimethyl-para-toluidine via oral or intraperitoneal injection at up to 1080 mg/kg-bw for up to 24 hours. DNA fragmentation increased in liver cells to about 2.4 times the control at the highest dose only and suggested that N,N-dimethyl-para-toluidine was weakly positive in this assay. Negative results were obtained when N,N-dimethyl-para-toluidine was tested in Balb/c mice. N,N-dimethyl-para-toluidine induced chromosomal effects in these assay. In a cytogenetic assay, Chinese Hamster V79 cells were exposed to N,N-dimethyl-para-toluidine up to 1.2mM without metabolic activation. Cytotoxicity was observed at 1.2 mM, where > 10% survival was estimated by colony formation. It is not clear if positive controls were used. N,N-dimethyl-para-toluidine induced chromosomal aberrations in this assay. CONCLUSIONS Under the conditions of these 2-year oral gavage studies, there was clear evidence of carcinogenic activity* of N,N-dimethyl-para-toluidine in male F344/N rats based on increased incidences of hepatocellular carcinoma, and hepatocellular adenoma or carcinoma (combined), and increased incidences of nasal cavity neoplasms (primarily nasal cavity transitional epithelium adenoma). The increased incidences of thyroid gland follicular cell neoplasms may have been related to treatment. There was clear evidence of carcinogenic activity of N,N-dimethyl-para-toluidine in female F344/N rats based on increased incidences of hepatocellular carcinoma and hepatocellular adenoma or carcinoma (combined). The occurrence of nasal cavity transitional epithelium adenoma was considered to be related to treatment. There was clear evidence of carcinogenic activity of N,N-dimethyl-para-toluidine in male B6C3F1/N mice based on increased incidences of hepatocellular adenoma (multiple), hepatocellular carcinoma, and hepatoblastoma. There was clear evidence of carcinogenic activity of N,N-dimethyl-para-toluidine in female B6C3F1/N mice based on increased incidences of hepatocellular adenoma, hepatocellular carcinoma, and hepatoblastoma and increased incidences of alveolar/ bronchiolar neoplasms (primarily adenoma). The increased incidences of forestomach squamous cell papilloma in female mice were considered to be related to treatment. Administration of N,N-dimethyl-para-toluidine resulted in increased incidences of nonneoplastic lesions of the liver and nasal cavity in male and female rats and mice; the kidney in male and female rats; the spleen and bone marrow in male and female rats and female mice; the lung in male and female mice; the forestomach in male rats and female mice; the mesenteric lymph node in male rats and female mice; and the olfactory lobe in male and female mice. N,N-dimethyl-para-toluidine also caused hematologic toxicity and increases in methemoglobin levels in male and female rats and mice (as measured at 3 months). N,N-dimethyl-para-toluidine's production and use as a polymerization accelerator in the manufacture of bone cements and dental materials, in industrial glues, and as an intermediate in dye and pesticide synthesis may result in its release to the environment through various waste streams. If released to air, a vapor pressure of 0.178 mm Hg at 25 °C indicates N,N-dimethyl-para-toluidine will exist solely as a vapor in the atmosphere. Vapor-phase N,N-dimethyl-para-toluidine will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 2 hrs. N,N-dimethyl-para-toluidine does not contains chromophores that absorb at wavelengths >290 nm and, therefore, is not expected to be susceptible to direct photolysis by sunlight. If released to soil, N,N-dimethyl-para-toluidine is expected to have moderate mobility based upon an estimated Koc of 260. The pKa of N,N-dimethyl-para-toluidine is 5.63, indicating that this compound will exist partially in the cation form in the environment and cations generally adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts. Volatilization of the neutral species from moist soil surfaces is expected to be an important fate process based upon an estimated Henry's Law constant of 7.0X10-5 atm-cu m/mole. N,N-dimethyl-para-toluidine is not expected to volatilize from dry soil surfaces based upon its vapor pressure. Biodegradation data in soil or water were not available. If released into water, N,N-dimethyl-para-toluidine is not expected to adsorb to suspended solids and sediment based upon the estimated Koc. Volatilization from water surfaces is expected to be an important fate process based upon this compound's estimated Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 1 and 10 days, respectively. An estimated BCF of 33 suggests the potential for bioconcentration in aquatic organisms is moderate. Hydrolysis is not expected to be an important environmental fate process since this compound lacks functional groups that hydrolyze under environmental conditions (pH 5 to 9). Occupational exposure to N,N-dimethyl-para-toluidine may occur through inhalation and dermal contact with this compound at workplaces where N,N-dimethyl-para-toluidine is produced or used. N,N-dimethyl-para-toluidine's production and use as a polymerization accelerator in the manufacture of bone cements and dental materials, in industrial glues, and as an intermediate in dye and pesticide synthesis may result in its release to the environment through various waste streams. Based on a classification scheme, an estimated Koc value of 260, determined from a log Kow of 2.81 and a regression-derived equation, indicates that N,N-dimethyl-para-toluidine is expected to have moderate mobility in soil. The pKa of N,N-dimethyl-para-toluidine is 5.63, indicating that this compound will exist partially in the cation form in the environment and cations generally adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts. Volatilization of the neutral species of N,N-dimethyl-para-toluidine from moist soil surfaces is expected to be an important fate process given an estimated Henry's Law constant of 7.0X10-5 atm-cu m/mole, derived from its vapor pressure, 0.178 mm Hg, and water solubility, 455 mg/L. N,N-dimethyl-para-toluidine is not expected to volatilize from dry soil surfaces based upon its vapor pressure. Biodegradation data in soil were not available. According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere, N,N-dimethyl-para-toluidine, which has a vapor pressure of 0.178 mm Hg at 25 °C, is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase N,N-dimethyl-para-toluidine is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 2 hrs, calculated from its rate constant of 2.0X10-10 cu cm/molecule-sec at 25 °C that was derived using a structure estimation method. N,N-dimethyl-para-toluidine does not contain chromophores that absorb at wavelengths >290 nm and, therefore, is not expected to be susceptible to direct photolysis by sunlight. The rate constant for the vapor-phase reaction of N,N-dimethyl-para-toluidine with photochemically-produced hydroxyl radicals has been estimated as 2.0X10-10 cu cm/molecule-sec at 25 °C using a structure estimation method. This corresponds to an atmospheric half-life of about 2 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm. N,N-dimethyl-para-toluidine is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions. N,N-dimethyl-para-toluidine does not contain chromophores that absorb at wavelengths >290 nm and, therefore, is not expected to be susceptible to direct photolysis by sunlight. The Koc of N,N-dimethyl-para-toluidine is estimated as 260, using a log Kow of 2.81 and a regression-derived equation. According to a classification scheme, this estimated Koc value suggests that N,N-dimethyl-para-toluidine is expected to have moderate mobility in soil. The pKa of N,N-dimethyl-para-toluidine is 5.63, indicating that this compound will exist partially in the cation form and cations generally adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts. A Kd value of 380 for sorption to monmorillonite has been reported. The Henry's Law constant for N,N-dimethyl-para-toluidine is estimated as 7.0X10-5 atm-cu m/mole derived from its vapor pressure, 0.178 mm Hg, and water solubility, 455 mg/L. This Henry's Law constant indicates that N,N-dimethyl-para-toluidine is expected to volatilize from water surfaces. Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec) is estimated as 1 day. The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec) is estimated as 10 days. N,N-dimethyl-para-toluidine's estimated Henry's Law constant indicates that volatilization from moist soil surfaces may occur. N,N-dimethyl-para-toluidine is not expected to volatilize from dry soil surfaces based upon its vapor pressure. About N,N-dimethyl-para-toluidine N,N-dimethyl-para-toluidine is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum. N,N-dimethyl-para-toluidine is used by professional workers (widespread uses), in formulation or re-packing and at industrial sites. Consumer Uses of N,N-dimethyl-para-toluidine ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the routes by which N,N-dimethyl-para-toluidine is most likely to be released to the environment. Article service life of N,N-dimethyl-para-toluidine ECHA has no public registered data on the routes by which N,N-dimethyl-para-toluidine is most likely to be released to the environment. ECHA has no public registered data indicating whether or into which articles the substance might have been processed. Widespread uses by professional workers of N,N-dimethyl-para-toluidine N,N-dimethyl-para-toluidine is used in the following products: pH regulators and water treatment products, adhesives and sealants, leather treatment products and laboratory chemicals. N,N-dimethyl-para-toluidine is used in the following areas: health services and scientific research and development. N,N-dimethyl-para-toluidine is used for the manufacture of: textile, leather or fur. Other release to the environment of N,N-dimethyl-para-toluidine is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners). Formulation or re-packing of N,N-dimethyl-para-toluidine N,N-dimethyl-para-toluidine is used in the following products: adhesives and sealants. Release to the environment of N,N-dimethyl-para-toluidine can occur from industrial use: formulation of mixtures. Uses at industrial sites of N,N-dimethyl-para-toluidine N,N-dimethyl-para-toluidine is used in the following products: adhesives and sealants, textile treatment products and dyes, pH regulators and water treatment products and laboratory chemicals. N,N-dimethyl-para-toluidine has an industrial use resulting in manufacture of another substance (use of intermediates). N,N-dimethyl-para-toluidine is used in the following areas: formulation of mixtures and/or re-packaging, health services and scientific research and development. N,N-dimethyl-para-toluidine is used for the manufacture of: chemicals. Release to the environment of N,N-dimethyl-para-toluidine can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), in processing aids at industrial sites and as processing aid. Manufacture of N,N-dimethyl-para-toluidine ECHA has no public registered data on the routes by which N,N-dimethyl-para-toluidine is most likely to be released to the environment.
N,N-DIMETHYL-P-TOLUIDINE (DMPT)
N,N-Dimethyl-p-toluidine (DMPT) is a versatile organic compound extensively utilized in scientific research.
As a colorless, crystalline solid, N,N-Dimethyl-p-toluidine (DMPT) easily dissolves in most organic solvents.
N,N-Dimethyl-p-toluidine (DMPT) is an organic compound with formula (CH3)3C6H2NH2.

CAS Number: 99-97-8
Molecular Formula: C9H13N
Molecular Weight: 135.21
EINECS Number: 202-805-4

N,N-Dimethyl-p-toluidine, 99-97-8, N,N,4-TRIMETHYLANILINE, Dimethyl-p-toluidine, Benzenamine, N,N,4-trimethyl-, Dimethyl-4-toluidine, N,N-Dimethyl-4-methylaniline, N,N,4-Trimethylbenzenamine, p-Methyl-N,N-dimethylaniline, p-(Dimethylamino)toluene, N,N-Dimethyl-p-tolylamine, 4-Dimethylaminotoluene, N,N-Dimethyl-para-toluidine, p-Toluidine, N,N-dimethyl-, NSC 1785, p,N,N-Trimethylaniline, Dimetil-p-toluidina, N,N-Dimethyl-4-toluidine, 1-(Dimethylamino)-4-methylbenzene, 4,N,N-Trimethylaniline, S8XC5939VU, DTXSID0021832, NSC-1785, NL 65-100, DTXCID401832, p-N,N-Trimethylaniline, CAS-99-97-8, Dimetil-p-toluidina [Italian], CCRIS 1001, EINECS 202-805-4, UNII-S8XC5939VU, Benzeneamine,N,N,4-trimethyl-, dimethyltolylamine, HSDB 8202, MFCD00008316, N,4-Trimethylaniline, dimethyl-(p-tolyl)-amine, EC 202-805-4, Benzenamine,N,4-trimethyl-, SCHEMBL28378, MLS001050174, 4-dimethylamino-1-methylbenzene, 4,N,N-Trimethylaniline, 99%, CHEMBL1462714, DIMETHYLTOLYLAMINE [INCI], N,N-Dimethyl-p-methylphenylamine, NSC1785, Tox21_201370, Tox21_300062, AC-368, AKOS015915159, N,N-DIMETHYL-P-TOLUIDINE [IARC], NCGC00091397-01, NCGC00091397-02, NCGC00091397-03, NCGC00254201-01, NCGC00258922-01, SMR001216586, D0807, FT-0629511, FT-0636092, FT-0656134, NS00002247, E75885, EN300-7266829, 4,N,N-Trimethylaniline, purum, >=98.0% (GC), Q2051705, W-100002, Z1002998236, N,N-DIBENZYL-1,4,10,13-TETRAOXA-7,16-DIAZACYCLOOCTADECANE.

N,N-Dimethyl-p-toluidine (DMPT) is an aromatic amine that is of commercial interest as a precursor to dyes.
N,N-Dimethyl-p-toluidine (DMPT) is prepared by selective nitration of mesitylene, avoiding oxidation of the methyl groups, followed by reduction of the resulting nitro group to the aniline.
As a nucleophilic reagent capable of reacting with both electrophiles like carbonyl compounds and halides, as well as nucleophiles such as amines and alcohols.

With N,N-Dimethyl-p-toluidine (DMPT) is wide range of applications, N,N-Dimethyl-p-toluidine serves as a crucial reagent for the synthesis of various compounds in laboratory settings.
N,N-Dimethyl-p-toluidine (DMPT) is applications span across the synthesis of numerous compounds, including,agrochemicals, pesticides, amino acids, peptides, and nucleotides.
N,N-Dimethyl-p-toluidine (DMPT) is a tertiary amine that can undergo iron-catalyzed oxidative C-C coupling with phenylacetylene and benzamide in the presence of tert-butylperoxide to form N,4-dimethyl-N-(3-phenylprop-2-ynyl)benzenamine and N-((methyl(p-tolyl)amino)methyl)benzamide, respectively.

N,N-Dimethyl-p-toluidine (DMPT) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.
N,N-Dimethyl-p-toluidine (DMPT) is presented to the CSWG for review because it is a highproduction-volume chemical that has the potential for widespread human exposure from its use in dental materials and bone cements.
N,N-Dimethyl-p-toluidine (DMPT) is used in the following products: pH regulators and water treatment products, adhesives and sealants, leather treatment products and laboratory chemicals.

N,N-Dimethyl-p-toluidine (DMPT) is used in the following areas: health services and scientific research and development. N,N-dimethyl-para-toluidine is used for the manufacture of: textile, leather or fur.
N,N-Dimethyl-p-toluidine (DMPT) is used in the following products: adhesives and sealants.
Release to the environment of N,N-Dimethyl-p-toluidine (DMPT) can occur from industrial use: formulation of mixtures.

N,N-Dimethyl-p-toluidine (DMPT) is used in the following products: adhesives and sealants, textile treatment products and dyes, pH regulators and water treatment products and laboratory chemicals.
N,N-Dimethyl-p-toluidine (DMPT) has an industrial use resulting in manufacture of another substance (use of intermediates).
N,N-Dimethyl-p-toluidine (DMPT) is the accelerator in the redox initiator-accelerator system used commercially to cure methyl methacrylate monomers.

Polymerization is rarely complete; N,N-Dimethyl-p-toluidine (DMPT) retained in bone cements and dental materials is sufficient to cause exposure to surgical staff, dental prosthetic device manufacturers, and denture wearers, among others.
Other release to the environment of N,N-Dimethyl-p-toluidine (DMPT) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).
N,N-Dimethyl-p-toluidine (DMPT) finds utility in the creation of polymers, dyes, and catalysts.

N,N,4-trimethylaniline is a chemical compound with the molecular formula C9H13N.
N,N-Dimethyl-p-toluidine (DMPT) is thought to be the causative agent in “burning mouth” observed in denture wearers and it may be responsible for aseptic loosening of hip replacements
N,N-Dimethyl-p-toluidine (DMPT) is used in the following areas: formulation of mixtures and/or re-packaging, health services and scientific research and development.

N,N-Dimethyl-p-toluidine (DMPT) is used for the manufacture of: chemicals
N,N-Dimethyl-p-toluidine (DMPT) is a building block to a variety of bulky ligands.
Condensation with glyoxal gives the 1,2-diimine ligands.

An example is glyoxal-bis(mesitylimine), a yellow solid that is synthesized by condensation of 2,4,6-trimethylaniline and glyoxal.
The diimine is a useful precursor to popular NHC ligands including IMes.
N,N-Dimethyl-p-toluidine (DMPT), as found in 2nd generation Grubbs' catalyst, are also prepared from this compound.

The metabolism of orally administered N,N-Dimethyl-p-toluidine (DMPT) in male F344 rats was investigated.
The rat urinary metabolite profile was determined by analytical reverse-phase high performance liquid chromatography (HPLC).
Four radiolabeled peaks were observed, isolated, and purified by solid-phase extraction (SPE) and preparative HPLC methods.

The 4 peaks were identified as p-(Nacetylhydroxyamino)hippuric acid (M1), N,N-dimethyl-para-toluidine N-oxide (M2), N-methyl-p-toluidine (M3), and parent N,Ndimethyl-para-toluidine.
Metabolites M1 and M2 were identified by spectrometric and spectroscopic methods, including mass fragmentation pattern identification from both liquid chromatography/mass spectrometry and gas chromatography/mass spectrometry, and from chemical analysis of nuclear magnetic resonance spectra.
Structural confirmation of metabolite M2 was accomplished by comparison with a synthetic standard.

Peaks M3 and the peak suspected to be N,N-Dimethyl-p-toluidine (DMPT) were identified by comparison of their HPLC retention times and mass fragmentation patterns with authentic standards of N-methyl-ptoluidine and N,N-dimethyl-para-toluidine, respectively.
N,N-Dimethyl-p-toluidine (DMPT) is an aromatic amine, specifically a derivative of aniline where three methyl groups (-CH3) are substituted onto the nitrogen atom of the amine group.

N,N-Dimethyl-p-toluidine (DMPT) is a N-methyl-N-alkylaniline.
N,N-Dimethyl-p-toluidine (DMPT) is reaction with vinyl ether catalyzed by CuCl2 has been reported to afford tetrahydroquinolines.
N,N-Dimethyl-p-toluidine (DMPT) metabolism is similar to that reported for N,Ndimethylaniline.

N,N-Dimethyl-p-toluidine (DMPT) has a triarylamine structure with one 2,4,6-methylated phenyl and two 4-brominated phenyl rings.
The two bromo functional groups at the end of each benzene rings enable it to extend its conjugation via Suzuki, Yamamoto or Stille coupling reactions.
N,N-Dimethyl-p-toluidine (DMPT) is a convenient intermediate for the synthesis of polytriarylamines (PTAAs) via Yamamoto polycondensation.

PTAAs are electron rich thus commonly used as electron transport layer for perovskite solar cells and OLED devices.
PTAAs can normally be deposited by solution processing at lower temperature, significantly reducing possible thermal damage to the active layer.
N,N-Dimethyl-p-toluidine (DMPT) is prepared from the reaction of 2,4,6-trimethylaniline with 1-bromo-4-iodobenzene (Buchwald-Hartwig amination) in the presence of 1,1′-ferrocenediyl-bis(diphenylphosphine) (dppf) and sodium tert-butoxide in toluene.

N,N-Dimethyl-p-toluidine (DMPT) showed greater elution than MMA.
The hydrophilic portion of Yunifast was more cytotoxic than the hydrophobic portion, and contained BA and p-toluidine as major and minor components.
The /study/ conclude that the rigidity of the material is critical to the extractable quantity, and recommend that both Yunifast and Acron be immersed in hot water before use in order to remove hydrophilic toxic compounds from these pMMA dental materials.

The National Occupational Exposure Survey, which was conducted by the National Institute for Occupational Safety and Health (NIOSH) between 1981 and 1983, estimated that 62,720 workers were potentially exposed to N,N-Dimethyl-p-toluidine (DMPT) in the workplace (NIOSH, 1990).
There is potential for widespread human exposure to N,N-dimethyl-para-toluidine in occupational settings where bone cements, dental prostheses, industrial glues, and artificial fingernails are manufactured or used.
Exposure to N,N-Dimethyl-p-toluidine (DMPT) may be a concern because of the possible release of unreacted chemicals from polymeric composites.

The rate constant for the vapor-phase reaction of N,N-Dimethyl-p-toluidine (DMPT) with photochemically-produced hydroxyl radicals has been estimated as 2.0X10-10 cu cm/molecule-sec at 25 °C using a structure estimation method.
This corresponds to an atmospheric half-life of about 2 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm.
N,N-Dimethyl-p-toluidine (DMPT) is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions.

N,N-Dimethyl-p-toluidine (DMPT) does not contain chromophores that absorb at wavelengths >290 nm and, therefore, is not expected to be susceptible to direct photolysis by sunlight.
Being a tertiary amine, N,N-Dimethyl-p-toluidine (DMPT) is less basic than primary or secondary amines.
However, N,N-Dimethyl-p-toluidine (DMPT) can still act as a weak base in chemical reactions.

N,N-Dimethyl-p-toluidine (DMPT) can be synthesized through various methods, including the alkylation of aniline using methylating agents.
The specific synthetic route may depend on the intended application.
N,N-Dimethyl-p-toluidine (DMPT) and related aromatic amines can find applications in various industrial processes.

They may be used in the synthesis of dyes, pigments, pharmaceuticals, and other specialty chemicals.
Aromatic amines, including N,N-Dimethyl-p-toluidine (DMPT), are important intermediates in the synthesis of azo dyes.
Azo dyes are a significant class of synthetic dyes widely used in the textile and other industries.

N,N-Dimethyl-p-toluidine (DMPT) can serve as a chemical intermediate in the synthesis of various compounds.
N,N-Dimethyl-p-toluidine (DMPT) is reactivity allows for the creation of diverse chemical structures.
Like many aromatic amines, N,N-Dimethyl-p-toluidine (DMPT) may pose health and safety risks, and precautions should be taken when handling this compound.

N,N-Dimethyl-p-toluidine (DMPT) is a clear to yellow liquid with an aromatic odor; insoluble in water.
N,N-Dimethyl-p-toluidine (DMPT) is an accelerator in the redox initiator-accelerator system used commercially to cure methyl methacrylate monomers.
N,N-Dimethyl-p-toluidine (DMPT) is a high-production volume chemical with potential for widespread human exposure through its use in dental materials and bone cements.

N,N-Dimethyl-p-toluidine (DMPT) has been used in the preparation of acrylic denture materials for the past 50 years.
N,N-Dimethyl-p-toluidine (DMPT) belongs to the class of substituted anilines, which are organic compounds containing an amino group attached to a benzene ring.
The presence of the three methyl groups makes N,N-Dimethyl-p-toluidine (DMPT) a tertiary amine.

N,N-Dimethyl-p-toluidine (DMPT), is the ingredient that induces the reaction giving rise to free radicals capable of initiating polymerization of the acrylic monomers. Polymerization is rarely complete.
Five commercially available bone cements were analysed by high-performance liquid chromatography for detecting the residual content of an accelerator, the amine N,N-Dimethyl-p-toluidine (DMPT), after curing.
It was found that the concentration of N,N-Dimethyl-p-toluidine (DMPT) in aqueous extracts decreases with time, being almost
absent 7 days after curing.

Differences were noticed among the cements; residual N,N-Dimethyl-p-toluidine (DMPT) is higher in cements prepared with higher content of the amine.
N,N-Dimethyl-p-toluidine (DMPT) is verified that N,N-dimethyl-para-toluidine's toxic effect on cell cultures is dose-related; a delay in the cell replication cycle is induced in vitro.
Damage is reversible, thus justifying the low bone cement toxicity that is clinically ascertained.

The use of solid phase extraction (SPE) and high performance liquid chromatography (HPLC) for the analysis of toxic components eluted from methyl-methacrylate polymer (pMMA) dental materials was described.
N,N-Dimethyl-p-toluidine (DMPT) is used as the accelerator for the cement in most of the hip and bone replacements to activate the polymerization reaction.
N,N-Dimethyl-p-toluidine (DMPT) is found in industrial glues and artificial fingernail preparations and is used as an intermediate in dye and pesticide synthesis.

N,N-Dimethyl-p-toluidine (DMPT) is a fine chemical that belongs to the family of aminomethyl compounds.
N,N-Dimethyl-p-toluidine (DMPT)'s estimated Henry's Law constant indicates that volatilization from moist soil surfaces may occur.
N,N-Dimethyl-p-toluidine (DMPT) is not expected to volatilize from dry soil surfaces based upon its vapor pressure.

N,N-Dimethyl-p-toluidine (DMPT) is a versatile building block that can be used in the synthesis of complex compounds and as a reagent or speciality chemical in research.
N,N-Dimethyl-p-toluidine (DMPT) is also a useful intermediate for reactions and scaffolds in organic syntheses.
N,N-Dimethyl-p-toluidine (DMPT) can be used as an alternative to the more commonly used 4-aminophenol.

This compound has been observed to have high purity and quality with no detectable impurities.
N,N-Dimethyl-p-toluidine (DMPT) is used as a polymerization accelerator in the manufacture of bone cements and dental materials, in industrial glues, and as an intermediate in dye and pesticide synthesis.
Thus, there is potential for human exposure to N,N-Dimethyl-p-toluidine (DMPT), an aromatic amine with a structural alert for potential DNA reactivity.

The National Toxicology Program (NTP) is evaluating the toxicity and carcinogenicity of
N,N-Dimethyl-p-toluidine (DMPT) in male and female Fischer 344 rats and B6C3F1 mice.
N,N-Dimethyl-p-toluidine (DMPT) is radical cation undergoes reaction with the anthracene radical anion and generation of electrogenerated chemiluminescence (ECL) has been observed.

Melting point: -25°C
Boiling point: 211 °C(lit.)
Density: 0.937 g/mL at 25 °C(lit.)
vapor density: >1 (vs air)
vapor pressure: 0.1 hPa (20 °C)
refractive index: n20/D 1.546(lit.)
Flash point: 182 °F
storage temp.: Store below +30°C.
solubility: 0.65g/l
form: Liquid
pka: pK1:7.24(+1) (25°C)
color: Clear yellow
explosive limit 7%
Water Solubility: Miscible with alcohol, ether and chloroform. Immiscible with water.
BRN: 774409
Dielectric constant: 3.3(20℃)
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey: GYVGXEWAOAAJEU-UHFFFAOYSA-N
LogP: 1.729-2.81 at 35℃

N,N-Dimethyl-p-toluidine (DMPT) has been used in the preparation of acrylic denture materials for the past 50 years.
N,N-Dimethyl-p-toluidine (DMPT) is reactivity allows it to participate in a variety of chemical reactions.
Some aromatic amines, including certain derivatives, are known to exhibit catalytic activity in specific reactions.

Researchers may explore their catalytic potential in various transformations.
The use of the term N,N-Dimethyl-p-toluidine (DMPT) suggests the presence of three methyl groups on the nitrogen atom.
The specific isomerism, stereochemistry, and substitution pattern on the aromatic ring can affect the compound's properties.

Aromatic amines, including N,N-Dimethyl-p-toluidine (DMPT), can be analyzed using various analytical techniques, such as chromatography and spectroscopy.
These methods are employed for identification and quantification in research and industrial settings.
Like many chemical compounds, N,N-Dimethyl-p-toluidine (DMPT) requires careful handling due to potential health hazards.

This includes the use of appropriate personal protective equipment, adherence to safety protocols, and awareness of its potential toxicity.
Aromatic amines are commonly employed in research laboratories for their versatility in organic synthesis.
Researchers may study their properties and reactivity to develop new methodologies or create novel compounds.

Some aromatic amines serve as building blocks in the synthesis of pharmaceuticals and bioactive compounds.
N,N-Dimethyl-p-toluidine (DMPT) is used as the accelerator for the cement in most of the hip and bone replacements to activate the polymerization reaction at concentrations ranging from 0.7% to 2.6%.
N,N-Dimethyl-p-toluidine (DMPT) is found in industrial glues and artificial fingernail preparations and is used as an intermediate in dye and pesticide synthesis.

N,N-Dimethyl-p-toluidine (DMPT) has a shorter setting time (11.5 minutes) than some alternative accelerators.
As an aromatic amine, N,N-Dimethyl-p-toluidine (DMPT) exhibits reactivity typical of such compounds.
N,N-Dimethyl-p-toluidine (DMPT) can undergo reactions like aromatic substitution, where the hydrogen atoms on the aromatic ring can be replaced by other functional groups.

Some aromatic amines, depending on their structures, have been studied for their potential impact on biological systems and the environment.
Aromatic amines may find applications in biocatalysis and enzymatic reactions, where certain enzymes can catalyze specific transformations involving these compounds.
Acryl resins used in dental practice are blends of poly(methyl methacrylated) particles and methyl methacrylate monomer, or copolymers of methyl methacrylate with styrene or other acrylic monomers.

This blend is a slurry of high viscosity that is hardened by the free radical polymerization of the monomeric components.
N,N-Dimethyl-p-toluidine (DMPT)'s production and use as a polymerization accelerator in the manufacture of bone cements and dental materials, in industrial glues, and as an intermediate in dye and pesticide synthesis may result in its release to the environment through various waste streams.
If released to air, a vapor pressure of 0.178 mm Hg at 25 °C indicates N,N-Dimethyl-p-toluidine (DMPT) will exist solely as a vapor in the atmosphere.

Vapor-phase N,N-dimethyl-para-toluidine will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 2 hrs.
N,N-Dimethyl-p-toluidine (DMPT) does not contains chromophores that absorb at wavelengths >290 nm and, therefore, is not expected to be susceptible to direct photolysis by sunlight.
If released to soil, N,N-Dimethyl-p-toluidine (DMPT) is expected to have moderate mobility based upon an estimated Koc of 260.

The pKa of N,N-Dimethyl-p-toluidine (DMPT) is 5.63, indicating that this compound will exist partially in the cation form in the environment and cations generally adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts.
Volatilization of the neutral species from moist soil surfaces is expected to be an important fate process based upon an estimated Henry's Law constant of 7.0X10-5 atm-cu m/mole.
N,N-Dimethyl-p-toluidine (DMPT) is not expected to volatilize from dry soil surfaces based upon its vapor pressure.

Biodegradation data in soil or water were not available.
If released into water, N,N-Dimethyl-p-toluidine (DMPT) is not expected to adsorb to suspended solids and sediment based upon the estimated Koc.
Volatilization from water surfaces is expected to be an important fate process based upon this compound's estimated Henry's Law constant.

Estimated volatilization halflives for a model river and model lake are 1 and 10 days, respectively.
An estimated BCF of 33 suggests the potential for bioconcentration in aquatic organisms is moderate.
Hydrolysis is not expected to be an important environmental fate process since this compound lacks functional groups that hydrolyze under environmental conditions (pH 5 to 9).

Occupational exposure to N,N-Dimethyl-p-toluidine (DMPT) may occur through inhalation and dermal contact with this compound at workplaces where N,N-dimethyl-para-toluidine is produced or used.
These compounds may be subject to regulations to minimize their release and exposure.
N,N-Dimethyl-p-toluidine (DMPT), like other aromatic amines, can be utilized in organic synthesis for the preparation of various organic compounds.

N,N-Dimethyl-p-toluidine (DMPT) neutralizes acids in exothermic reactions to form salts plus water.
May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.

N,N-Dimethyl-p-toluidine (DMPT) is an accelerator in the redox initiator-accelerator system used commercially to cure methyl methacrylate monomers.
Polymerization is rarely complete.
N,N-Dimethyl-p-toluidine (DMPT) is a high-production volume chemical with potential for widespread human exposure through its
use in dental materials and bone cements.

Uses:
N,N-Dimethyl-p-toluidine (DMPT) is likely used in research laboratories for organic synthesis and chemical studies.
N,N-Dimethyl-p-toluidine (DMPT) is reactivity and properties may be explored in the development of new methodologies or understanding structure-activity relationships.
In research and educational settings, N,N-Dimethyl-p-toluidine (DMPT) may be used as a reagent in various laboratory experiments and demonstrations.

Some aromatic amines may have the ability to form complexes with metal ions, which can have applications in areas such as metal extraction and separation.
In metal surface treatment processes, aromatic amines might be employed as additives or components in formulations to enhance surface properties.
Certain aromatic amines are investigated for their electrochemical properties, making them potential candidates for use in batteries, sensors, or other electrochemical devices.

Some aromatic amines have been studied in the context of cancer research due to their potential mutagenic and carcinogenic properties.
Understanding their effects can contribute to cancer prevention strategies.
Aromatic amines may be involved in supramolecular chemistry studies, exploring the assembly of molecules into larger, organized
structures through non-covalent interactions.

In the field of tissue engineering, certain aromatic amines may be explored for their potential role in the development of biomaterials and scaffolds.
Some aromatic amines with specific optical properties are investigated for their potential use in photothermal therapy, a medical treatment that utilizes light-absorbing substances to generate heat and selectively destroy targeted cells.
Certain aromatic amines are studied for their potential as hydrogen storage materials in the context of alternative energy research.

Aromatic amines, due to their chemical properties, may be involved in certain wastewater treatment processes for the removal of pollutants and contaminants.
In the plastics and textile industries, certain aromatic amines are utilized as antistatic agents to reduce static electricity buildup.
Aromatic amines, particularly those with specific electronic properties, are investigated for their potential use in gas sensing devices for the detection of gases and vapors.

Some aromatic amines play a role in the development of materials used in photovoltaic devices and solar cells.
Aromatic amines may be included in formulations for surface coatings to enhance adhesion, flexibility, and resistance to environmental factors.
In the field of agrochemicals, certain aromatic amines may be components of formulations for pesticides or plant growth regulators.

Aromatic amines are subjects of study in material science, where their properties and reactivity are explored for the design and development of new materials with specific functionalities.
Aromatic amines can be involved as catalysts in certain hydrogenation reactions, facilitating the addition of hydrogen to unsaturated compounds.
In certain metal extraction processes, aromatic amines may be used as extractants for the separation of metals from ores or solutions.

Aromatic amines, including N,N,4-trimethylaniline, may find applications in the polymer industry.
They can be used as monomers or additives in the synthesis of certain polymers.
Some aromatic amines are utilized in the formulation of adhesives, where they can contribute to the chemical and physical properties of the adhesive.

Certain aromatic amines may have antioxidant properties.
While the specific antioxidant properties of N,N,4-trimethylaniline need to be assessed, some aromatic amines are known for their ability to inhibit oxidation.
Aromatic amines have historical applications in the field of photography.

They were used in the formulation of certain photographic chemicals and processes.
Some aromatic amines are investigated for their potential use as corrosion inhibitors.
They may be employed to protect metals from corrosion in certain industrial applications.

Aromatic amines, including certain derivatives, have been used as color developers in the photographic industry, contributing to the formation of color images.
Aromatic amines may be used as auxiliaries in the textile industry for processes such as dyeing and finishing.
N,N-Dimethyl-p-toluidine (DMPT) is an amine accelerator for the polymerization of e.g. dental methacrylic restorative materials.

N,N-Dimethyl-p-toluidine (DMPT) is used as a polymerization catalyst for polyesters, acrylate and epoxy resins.
N,N-Dimethyl-p-toluidine (DMPT) is also used as a hardener for dental cements and in adhesives.
N,N-Dimethyl-p-toluidine (DMPT) serves as an intermediate for photographic chemicals, in industrial glues, in artificial fingernail preparations, colorants, pharmaceuticals.

N,N-Dimethyl-p-toluidine (DMPT) reacts with vinyl ether in the presence of copper(II) chloride gives tetrahydroquinolines.
Further, N,N-Dimethyl-p-toluidine (DMPT) is used to accelerate polymerization of ethyl methacrylate.
Aromatic amines, including N,N-Dimethyl-p-toluidine (DMPT), are important intermediates in the synthesis of azo dyes.

These dyes are widely used in the textile industry for coloring fabrics.
Aromatic amines can be used as intermediates in the synthesis of pharmaceutical compounds.
They may play a role in the creation of specific drug molecules or building blocks.

N,N-Dimethyl-p-toluidine (DMPT), like other aromatic amines, can participate in various chemical reactions, making it valuable in the synthesis of diverse organic compounds.
Some aromatic amines exhibit catalytic properties and may be employed in catalytic processes.

Health Hazard:
Inhalation, ingestion or skin contact with material may cause severe injury or death.
Contact with molten N,N-Dimethyl-p-toluidine (DMPT) may cause severe burns to skin and eyes.
Avoid any skin contact.

Fire Hazard:
Combustible material: may burn but does not ignite readily.
When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards.
Contact with metals may evolve flammable hydrogen gas.

Safety Profile:
Prolonged or repeated exposure to these compounds may increase the risk of developing cancer.
Certain aromatic amines are mutagenic, meaning they have the potential to cause genetic mutations.
Mutations can lead to various health issues, including cancer.

Aromatic amines can be toxic, and exposure to them may cause adverse health effects.
The specific toxicity can vary among different aromatic amines and depends on factors such as chemical structure, concentration, and duration of exposure.
Aromatic amines may cause irritation to the skin and eyes upon contact.

Skin exposure can lead to dermatitis, and eye exposure may result in irritation or damage.
Some aromatic amines are known or suspected carcinogens, meaning they have the potential to cause cancer.
Inhalation of vapors or dust containing aromatic amines may irritate the respiratory system, leading to symptoms such as coughing, difficulty breathing, or irritation of the nose and throat.

N,N'-DIMETHYLUREA
N,N'-Dimethylurea, an alkyl urea derivative, is a nonlinear organic material.
N,N’-Dimethylurea is a urea derivative and used as an intermediate in organic synthesis.
N,N'-Dimethylurea forms needle-shaped crystals.


CAS Number: 96-31-1
EC Number: 202-498-7
MDL number: MFCD00008286
Linear Formula: (CH3NH)2CO
Chemical formula: C3H8N2O



SYNONYMS:
1,3-Dimethylurea, sym-dimethylurea, N,N-Dimethylurea, n,n'-dimethyl-ure, N,N'-dimethylurea, Dimethyl Urea 1,3, symmetricdimethylurea, symmetric dimethylurea, n,n'-dimethylharnstoff, Symmetric dimethylurea, N,N'-Dimethylharnstoff, N,N-dimethylurea (sym.), 1,3-Dimethylurea Factory, N,N'-Dimethylurea Factory, 1,3-Dimethylurea COA TDS MSDS, 1,3-DIMETHYLUREA, N,N'-Dimethylurea, 96-31-1, sym-Dimethylurea, Urea, N,N'-dimethyl-, Symmetric dimethylurea, Urea, 1,3-dimethyl-, 1,3-Dimethyl urea, N,N'-Dimethylharnstoff, dimethyl urea, NSC 14910, BRN 1740672, AI3-24386, MFCD00008286, WAM6DR9I4X, DTXSID5025156, CHEBI:80472, Urea,3-dimethyl-, Urea,N'-dimethyl-, NSC-14910, 1,3-Dimethylurea, 98%, WLN: 1MVM1, CCRIS 2509, HSDB 3423, EINECS 202-498-7, UNII-WAM6DR9I4X, Dimethylharnstoff, 1.3-Dimethylurea, N,N-Dimethyl-Urea, 1,3 dimethyl urea, N,N'-dimethyl urea, N,N'-dimethylurea, 1,1'-Dimethylurea, 1,3-Dimethylcarbamide, 3k3g, bmse000248, EC 202-498-7, UREA,1,3-DIMETHYL, (CH3NH)2CO, DIMETHYL UREA [INCI], DIMETHYLUREA, N,N'-, N,N'-Dimethylurea, ~98%, DTXCID605156, CHEMBL1234380, 1,3-DIMETHYLUREA [HSDB], NSC14910, NSC24823, Tox21_200794, 1,3-Dimethylurea;N,N'-Dimethylurea, BBL011513, NSC-24823, STL146629, AKOS000120912, CS-W013749, PB47928, CAS-96-31-1, NCGC00248834-01, NCGC00258348-01, SY004507, DB-225923, N,N inverted exclamation mark-Dimethylurea, N,N inverted exclamation marka-Dimethylurea, A4569, D0289, NS00005754, EN300-20740, P17517, ethyl 5-oxo-2,3-diphenyl-cyclopentanecarboxylate, A845576, N,N'-Dimethylurea, (sym.), >=99% (from N), Q419740, W-100145, N,N'-Dimethylurea, PESTANAL(R), analytical standard, F0001-2292, N,N'-Dimethylurea, (sym.), >=95.0% (HPLC), technical, InChI=1/C3H8N2O/c1-4-3(6)5-2/h1-2H3,(H2,4,5,6, DMU, 1,3-Dimethylurea, N,N′-Dimethylurea, Urea,N,N’-dimethyl,UNII-, AM6DR9I4X, MeNHNCONHMe, sym-Dimethylurea,N,N`-Dimethylurea, Expand DMU, N,N'-Dimethylharnstoff [German], N,N'-Dimethylurea, Symmetric dimethylurea, sym-Dimethylurea, Urea, 1,3-dimethyl-, Urea, N,N'-dimethyl-, N,N′-Dimethylurea, DMU, 1,3-Dimethylurea, 1,3-DIMETHYLUREA, N,N'-Dimethylurea, 96-31-1, sym-Dimethylurea, Urea, N,N'-dimethyl-, Symmetric dimethylurea, Urea, 1,3-dimethyl-, N,N'-Dimethylharnstoff, 1,3-Dimethyl urea, NSC 14910, BRN 1740672, AI3-24386, MFCD00008286, WAM6DR9I4X, DMU, DTXSID5025156, CHEBI:80472, Urea,3-dimethyl-, Urea,N'-dimethyl-, NSC-14910, 1,3-Dimethylurea, 98%, WLN: 1MVM1, CCRIS 2509, HSDB 3423, EINECS 202-498-7, UNII-WAM6DR9I4X, Dimethylharnstoff, 1.3-Dimethylurea, N,N-Dimethyl-Urea, 1,3 dimethyl urea, N,N'-dimethyl urea, 1,1'-Dimethylurea, 1,3-Dimethylcarbamide, bmse000248, EC 202-498-7, UREA,1,3-DIMETHYL, (CH3NH)2CO, DIMETHYL UREA [INCI], DIMETHYLUREA, N,N'-, N,N'-Dimethylurea, ~98%, DTXCID605156, CHEMBL1234380, 1,3-DIMETHYLUREA [HSDB], NSC14910, NSC24823, Tox21_200794, 1,3-Dimethylurea;N,N'-Dimethylurea, NSC-24823, AKOS000120912, CS-W013749, PB47928, CAS-96-31-1, NCGC00248834-01, NCGC00258348-01, SY004507, N,N inverted exclamation mark -Dimethylurea, A4569, D0289, FT-0606700, EN300-20740, P17517, ethyl 5-oxo-2,3-diphenyl cyclopentanecarboxylate, A845576, N,N'-Dimethylurea, (sym.), >=99% (from N), Q419740, W-100145, N,N'-Dimethylurea, PESTANAL(R), analytical standard, F0001-2292, N,N'-Dimethylurea, (sym.), >=95.0% (HPLC), technical, InChI=1/C3H8N2O/c1-4-3(6)5-2/h1-2H3,(H2,4,5,6), Urea, 1,3-dimethyl-, sym-Dimethylurea, N,N'-Dimethylurea, Symmetric dimethylurea, 1,3-Dimethylurea, (CH3NH)2CO, 1,1'-Dimethylurea, DMU, N,N' Dimethylharnstoff, NSC 14910, (CH3NH)2CO, 1,1'-Dimethylurea, 1,3-dimethylurea, DMU, N,N'-Dimethylharnstoff, N,N'-dimethylurea, NSC 14910, Symmetric dimethylurea, sym-Dimethylurea, urea, 1,3-dimethyl-, syM,N,N'-DIMETHYLUREA, (CH3NH)2CO, AKOS B029718, 1.3-DiMethyl u, 1,3-dimethyl-ure, SYM-DIMETHYLUREA, 1,3-DIMETHYLUREA, n,n’-dimethyl-ure,Dimethylcarbamide, N,N'-Dimethyl urea, 1,3-Dimethylurea, N,N’-dimethyl-Urea, 1,3-dimethyl-ure, n,n’-dimethylharnstoff, n,n’-dimethylharnstoff (german), n,n’-dimethylurea, sym-dimethylurea, Urea, 1,3-dimethyl-, sym-Dimethylurea, N,N'-Dimethylurea, Symmetric dimethylurea, 1,3-Dimethylurea, (CH3NH)2CO, 1,1'-Dimethylurea, DMU, N,N'-Dimethylharnstoff, NSC 14910, Urea, N,N′-dimethyl-, Urea, 1,3-dimethyl-, N,N′-Dimethylurea, 1,3-Dimethylurea, Symmetric dimethylurea, sym-Dimethylurea, NSC 14910, NSC 24823, Urea,1,3-dimethyl- (8CI), N,N'-Dimethylurea, NSC 14910, NSC 24823, Symmetric dimethylurea, sym-Dimethylurea, Urea,N,N’-dimethyl, UNII-WAM6DR9I4X, MeNHNCONHMe, sym-Dimethylurea, N,N`-Dimethylurea, syM, N,N'-DIMETHYLUREA, (CH3NH)2CO, AKOS B029718, 1.3-DiMethyl u, 1,3-dimethyl-ure, SYM-DIMETHYLUREA, 1,3-DIMETHYLUREA, n,n’-dimethyl-ure, Dimethylcarbamide, n,n’-dimethylurea, sym-dimethylurea, urea, n,n’-dimethyl, dimethylurea, symmetric dimethylurea, urea, 1,3-dimethyl, n,n’-dimethylharnstoff, 1,3-dimethyl urea, n,n’-dimethylharnstoff german, unii-wam6dr9i4x, Urea, 1,3-dimethyl-, sym-Dimethylurea, N,N'-Dimethylurea, Symmetric dimethylurea, 1,3-Dimethylurea, (CH3NH)2CO, 1,1'-Dimethylurea, DMU, N,N'-Dimethylharnstoff, NSC 14910, Urea, 1,3-dimethyl-, sym-Dimethylurea, N,N'-Dimethylurea, Symmetric dimethylurea, 1,3-Dimethylurea, (CH3NH)2CO, 1,1'-Dimethylurea, DMU, N,N'-Dimethylharnstoff, NSC 14910, 1,1-DIMETHYLUREA, 598-94-7, N,N-Dimethylurea, Urea, N,N-dimethyl-, asym-Dimethylurea, Urea, 1,1-dimethyl-, 1320-50-9, 1,1-DIMETHYL-D6-UREA, 1.1-Dimethylurea, MFCD00007959, 1219802-32-0, NSC-33603, I988R763P3, 1,1-Dimethyl urea, N,N-Dimethylharnstoff, N,N-Dimethylharnstoff [German], HSDB 4273, EINECS 209-957-0, NSC 33603, BRN 1740666, AI3-61297, UNII-I988R763P3, N,N-dimethyl urea, EINECS 215-303-5, 1,1-dimethyl-urea, DIMETHYLUREA, N,N-, 1,1-Dimethylurea, 99%, (CH3)2NCONH2, DTXSID0060515, 1,1-DIMETHYLUREA [HSDB], NSC33603, STR03134, STL482999, AKOS000200400, SY048169, DB-053491, CS-0132397, D0809, NS00021239, EN300-17007, D-5580, D89723, A832531, Q24712449, InChI=1/C3H8N2O/c1-5(2)3(4)6/h1-2H3,(H2,4,6, n,n'-dimethylurea, sym-dimethylurea, urea, n,n'-dimethyl, dimethylurea, symmetric dimethylurea, urea, 1,3-dimethyl, n,n'-dimethylharnstoff, 1,3-dimethyl urea, n,n'-dimethylharnstoff german, unii-wam6dr9i4x



N,N'-Dimethylurea, an alkyl urea derivative, is a nonlinear organic material.
N,N’-Dimethylurea is soluble in water.
N,N’-Dimethylurea acts as a radical scavenger that protects isolated pancreatic islets from the effects of alloxan and dihydroxyfumarate exposure.
Methyl amine and N,N’-Dimethylurea are hydrolysis products of methyl isocyanate.


N,N’-Dimethylurea is a urea derivative and used as an intermediate in organic synthesis.
N,N’-Dimethylurea is a colorless crystalline powder with little toxicity.
N,N'-Dimethylurea forms needle-shaped crystals.


N,N'-Dimethylurea has been crystallized by using ethylacetate (solvent) and heptane (precipitant) by vapor diffusion technique.
N,N'-Dimethylurea's crystals has one molecule in each asymmetric unit.
N,N’-Dimethylurea is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 to < 10 tonnes per annum.


N,N’-Dimethylurea is an organic compound that has been shown to bind to the carbonyl group of proteins and act as a hydrogen-bond donor.
The nitrogen atoms are coordinated to form two pyramidal structures with the hydrogen bonding between the nitrogen atoms.
This coordination geometry leads to a molecule that is planar and the frequency shift of IR spectroscopy data confirms this structure.


The reaction mechanism for dimethyl urea begins with an attack by the oxygen atom on the carbon atom of tetramethylurea forming an intermediate called trimethylamine, which then reacts with trifluoroacetic acid (TFA) leading to the formation of dimethyl urea.
N,N’-Dimethylurea is a colorless crystalline powder with little toxicity.


Molecules in crystal are linked by hydrogen bonds.
N,N'-Dimethylurea is a colorless powder, used as building block for active ingredients or intermediate for formaldehyde-free textile additives.
N,N’-Dimethylurea is a white crystals


N,N’-Dimethylurea is a member of the class of ureas that is urea substituted by methyl groups at positions 1 and 3.
N,N’-Dimethylurea is a colorless crystals.
N,N’-Dimethylurea is water soluble.


N,N'-Dimethylurea is a member of the class of ureas that is urea substituted by methyl groups at positions 1 and 3.
N,N’-Dimethylurea is a colorless solid.
N,N’-Dimethylurea is a colorless powder.


N,N’-Dimethylurea is a colorless crystalline powder with little toxicity.
N,N’-Dimethylurea is a urea derivative and used as an intermediate in organic synthesis.
N,N’-Dimethylurea is a colorless crystalline powder with little toxicity.


N,N’-Dimethylurea is a member of the class of ureas that is urea substituted by methyl groups at positions 1 and 3.
N,N’-Dimethylurea is a solid in the form of white crystals with a faint ammonia-like odor.
N,N’-Dimethylurea is soluble in water.


N,N’-Dimethylurea is a colorless, volatile liquid with a penetrating odor.
N,N’-Dimethylurea is soluble in water and alcohols and has a melting point of -3°C.
N,N’-Dimethylurea is a solid in the form of white crystals with a faint ammonia-like odor.


N,N’-Dimethylurea is a urea derivative used as an intermediate in organic synthesis.
N,N’-Dimethylurea appears as colorless crystals and is a member of the class of ureas that is urea substituted by methyl groups at positions 1 and 3 .
N,N’-Dimethylurea is a urea derivative and used as an intermediate in organic synthesis.


N,N’-Dimethylurea is a colorless crystalline powder with little toxicity.
N,N’-Dimethylurea appears as colorless crystals.
N,N’-Dimethylurea is a member of the class of ureas that is urea substituted by methyl groups at positions 1 and 3.



USES and APPLICATIONS of N,N'-DIMETHYLUREA:
Typical applications of N,N'-Dimethylurea: Agriculture, Urea-herbicide, Carbamate-herbicide, and Textile additives.
N,N’-Dimethylurea is used for the manufacture of: chemicals.
Release to the environment of N,N’-Dimethylurea can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), in processing aids at industrial sites and as processing aid.


N,N’-Dimethylurea is a urea derivative and used as an intermediate in organic synthesis.
N,N’-Dimethylurea is a colorless crystalline powder with little toxicity.
N,N’-Dimethylurea is also used for synthesis of caffeine, pharmachemicals, textile aids, herbicides and other.


N,N'-Dimethylurea is used Formaldehyde-free textile additives.
N,N'-Dimethylurea is used cross linking agent for textiles made of cellulose fibers and their synthetic mixtures.
N,N'-Dimethylurea has used Pharmaceuticals.


In the textile processing industry N,N’-Dimethylurea is used as intermediate for the production of formaldehyde-free easy-care finishing agents for textiles.
In the Swiss Product Register there are 38 products containing N,N’-Dimethylurea, among them 17 products intended for consumer use.


Product types of N,N’-Dimethylurea are e.g. paints and cleaning agents.
The content of N,N’-Dimethylurea in consumer products is up to 10 %.
Use in cosmetics of N,N’-Dimethylurea has been proposed, but there is no information available as to its actual use in such applications.


N,N’-Dimethylurea is used for synthesis of caffeine, theophylline, pharmachemicals, textile aids, herbicides and others.
N,N’-Dimethylurea is used in the following areas: health services and scientific research and development.
Other release to the environment of N,N’-Dimethylurea is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).


Release to the environment of N,N’-Dimethylurea can occur from industrial use: formulation of mixtures.
N,N’-Dimethylurea is used in the following products: pH regulators and water treatment products and laboratory chemicals.
N,N’-Dimethylurea is used in the following areas: health services and scientific research and development.


N,N’-Dimethylurea is used as textile auxiliaries to produce formaldehyde-free anti-wrinkle finishing products.
N,N’-Dimethylurea is used in cosmetics as an emollient.
N,N’-Dimethylurea is used in medicine and can produce a variety of raw materials.


N,N'-Dimethylurea is a used reagant for the synthesis of active ingredients, such as bronchodilators.
N,N'-Dimethylurea can be used as a starting material to synthesize N,N'-dimethyl-6-amino uracil.
N,N’-Dimethylurea is used in chemical industry, it can synthesize a variety of chemical products.


N,N’-Dimethylurea is a urea derivative and used as an intermediate in organic synthesis.
N,N’-Dimethylurea is used for synthesis of caffeine, theophylline, pharmachemicals, textile aids, herbicides and others.
N,N’-Dimethylurea is used in the textile processing industry.


Pharmaceutical intermediates, N,N’-Dimethylurea is also used in the production of fiber treatment agents.
In medicine, N,N’-Dimethylurea is used to synthesize theophylline, caffeine and nifedipine hydrochloride, etc.
N,N’-Dimethylurea is used by professional workers (widespread uses), in formulation or re-packing and at industrial sites.


N,N’-Dimethylurea is used in the following products: pH regulators and water treatment products and laboratory chemicals.
N,N'-Dimethylurea is used in combination with ß-cyclodextrin derivatives, to form low melting mixtures (LMMs), which can be used as solvents for hydroformylation and Tsuji-Trost reactions.


N,N'-Dimethylurea is used to synthesize N,N'-disubstituted-4-aryl-3,4-dihydropyrimidinones via Biginelli condensation under solvent-free conditions.
N,N'-Dimethylurea is the suitable reagent used to investigate the polar structure of its crystals.
N,N’-Dimethylurea is used as a catalyst for condensation of methylamine with urea.


N,N’-Dimethylurea is used as a pharmaceutical drug to treat hyperammonemia.
N,N’-Dimethylurea is a urea derivative and used as an intermediate in organic synthesis.
N,N’-Dimethylurea is used in pharmaceutical manufacturing.


N,N’-Dimethylurea is used as an intermediate to make caffeine, pharmachemicals, textile aids, herbicides, paints, and cleaning products.
N,N’-Dimethylurea is used for synthesis of caffeine, pharmachemicals, textile aids, herbicides and other.
In the textile processing industry N,N’-Dimethylurea is used as intermediate for the production of formaldehyde-free easy-care finishing agents for textiles.


N,N’-Dimethylurea is used for synthesis of caffeine, theophylline, pharmachemicals, textile aids, herbicides and others.
In the textile processing industry N,N’-Dimethylurea is used as intermediate for the production of formaldehyde-free easy-care finishing agents for textiles.


The estimated world production of N,N’-Dimethylurea is estimated to be less than 25,000 tons.
N,N'-Dimethylurea may be used in the Dowex-50W ion exchange resin-promoted solvent-free synthesis of N,N′-disubstituted-4-aryl-3,4-dihydropyrimidinones.
N,N'-Dimethylurea is used for synthesis of caffeine, theophylline, pharmachemicals, textile aids, herbicides and others.


N,N’-Dimethylurea is used in the textile processing industry.
N,N’-Dimethylurea is used as an intermediate in organic synthesis. Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.


N,N’-Dimethylurea is used as an intermediate in the synthesis of theophylline and caffeine, and also used in the production of fiber treatment agents
N,N’-Dimethylurea is used in manufacturing synthetic caffeine, resins and drugs.
In the textile processing industry N,N'-Dimethylurea is used as intermediate for the production of formaldehyde-free easy-care finishing agents for textiles.


-N,N’-Dimethylurea can be used as a starting material to synthesize N,N′-dimethyl-6-amino uracil.
In combination with β-cyclodextrin derivatives, to form low melting mixtures (LMMs), which can be used as solvents for hydroformylation and Tsuji-Trost reactions.
To synthesize N,N′-disubstituted-4-aryl-3,4-dihydropyrimidinones via Biginelli condensation under solvent-free conditions.



PURIFICATION METHODS OF N,N'-DIMETHYLUREA:
Crystallise the urea from acetone/diethyl ether by cooling in an ice bath.
Also crystallise N,N’-Dimethylurea from EtOH and dry it at 50o/5mm for 24hours



FEATURES OF N,N'-DIMETHYLUREA:
*Good stability
N,N’-Dimethylurea has good stability and are suitable for various synthetic chemical reactions, ensuring the stability and reliability of our customers' production processes.



MOLECULAR STRUCTURE ANALYSIS OF N,N'-DIMETHYLUREA:
N,N’-Dimethylurea forms needle-shaped crystals .
The Raman spectra of DMU crystal have been measured, and the density function theory with a B3LYP/6-311G* * basis set has been used to optimize the geometry structure and calculate the vibrational frequency of gas phase DMU .



CHEMICAL REACTIONS ANALYSIS OF N,N'-DIMETHYLUREA:
The reaction of N,N’-Dimethylurea with formaldehyde has been studied in detail using quantitative on-line NMR spectroscopy.
The system undergoes only four reactions and, unlike urea–formaldehyde, does not form polymers .



SYNTHESIS ANALYSIS OF N,N'-DIMETHYLUREA:
A practically simple, mild, and efficient method has been developed for the synthesis of N-substituted ureas by nucleophilic addition of amines to potassium isocyanate in water without an organic co-solvent.



PRODUCTION METHOD OF N,N'-DIMETHYLUREA:
Industry uses molten urea and monomethyl amine action to make. First, the area into the melting tank, heated to 130-135C to melt N,N’-Dimethylurea, transferred to the reaction tower has been heated to 110-120C, continue to raise the temperature to 150-175 ℃, began to pass the purified monomethyl amine gas, until the monomethyl amine all through, that is, the reaction is completed, the creation of even dimethyl urea finished products.



REACTIVITY PROFILE OF N,N'-DIMETHYLUREA:
N,N’-Dimethylurea is an amide.
Amides are very weak bases (weaker than water).
Imides are less basic yet and in fact react with strong bases to form salts.

That is, they can react as acids.
Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile.
The combustion of these compounds generates mixed oxides of nitrogen (NOx).



PHYSICAL AND CHEMICAL PROPERTIES ANALYSIS OF N,N'-DIMETHYLUREA:
N,N’-Dimethylurea is a colorless crystalline powder with little toxicity .
The effects of concentration variation of 1,3-DMU in distilled water on dielectric and electrical properties have been discussed to gain information about the self-aggregative nature of N,N’-Dimethylurea and dissociation process in aqueous solutions



PHYSICAL AND CHEMICAL PROPERTIES OF N,N'-DIMETHYLUREA:
Character: gray-white, thin, thin, crystalline.
melting point 101~104 ℃
boiling point 268~270 ℃
relative density 1.142
solubility in water, ethanol, acetone, benzene and ethyl acetate, insoluble in ether and gasoline.



PHYSICAL and CHEMICAL PROPERTIES of N,N'-DIMETHYLUREA:
Physical state: flakes
Color: colorless
Odor: amine-like
Melting point/freezing point:
Melting point/range: 103 - 106 °C
Initial boiling point and boiling range: 268 - 270 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 157 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 9,0 - 9,5

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 765 g/l at 21,5 °C - soluble
Partition coefficient:
n-octanol/water: log Pow: -0,783
Vapor pressure: No data available
Density: 1,14 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available

Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Bulk density 0,50 g/l
Molecular Formula: CH3NHCONHCH3
CAS No: 96-31-1
EINECS: 202-498-7
Molecular Weight: 88.11
Appearance: White Crystals
Assay: ≥ 95%
Freezing point: 103'C Min
Volatile Content: ≤ 0.2%
Melting point: 104'C
CAS number: 96-31-1
EC number: 202-498-7
Hill Formula: C₃H₈N₂O

Molecular Weight: 88.11
Molecular Formula: C3H8N2O
Canonical SMILES: CNC(=O)NC
InChI: InChI=1S/C3H8N2O/c1-4-3(6)5-2/h1-2H3,(H2,4,5,6)
InChIKey: MGJKQDOBUOMPEZ-UHFFFAOYSA-N
Chemical formula: C3H8N2O
Molar mass: 88.110 g·mol−1
Appearance: Colorless, waxy crystals
Odor: Odorless
Density: 1.142 g mL−1
Melting point: 104.4 °C; 219.8 °F; 377.5 K
Boiling point: 269.1 °C; 516.3 °F; 542.2 K
Solubility in water: 765 g L−1
Magnetic susceptibility (χ): -55.1·10−6 cm3/mol

Thermochemistry:
Std enthalpy of formation (ΔfH⦵298): −312.1–−312.1 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): −2.0145–−2.0089 MJ mol−1
Additional Properties:
Molecular Weight: 88.11 g/mol
XLogP3: -0.5
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 0
Exact Mass: 88.063662883 g/mol
Monoisotopic Mass: 88.063662883 g/mol
Topological Polar Surface Area: 41.1Ų
Heavy Atom Count: 6
Formal Charge: 0
Complexity: 46.8

Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Appearance: Colorless crystals (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 108.00 °C. @ 760.00 mm Hg
Boiling Point: 269.00 °C. @ 760.00 mm Hg

Vapor Pressure: 0.547000 mmHg (est)
Flash Point: 116.00 °F. TCC (46.60 °C.) (est)
logP (o/w): -0.490
Soluble in water: 1.615e+004 mg/L @ 25 °C (est)
Chemical formula: C3H8N2O
Molar mass: 88.110 g·mol−1
Appearance: Colorless, waxy crystals
Odor: Odorless
Density: 1.142 g mL−1
Melting point: 104.4 °C; 219.8 °F; 377.5 K
Boiling point: 269.1 °C; 516.3 °F; 542.2 K

Solubility in water: 765 g L−1
Magnetic susceptibility (χ): -55.1·10−6 cm3/mol
Thermochemistry:
Std enthalpy of formation (ΔfH⦵298): −312.1–−312.1 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): −2.0145–−2.0089 MJ mol−1
Molecular Weight: 88.11 g/mol
XLogP3: -0.5
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 0
Exact Mass: 88.063662883 g/mol
Monoisotopic Mass: 88.063662883 g/mol

Topological Polar Surface Area: 41.1Ų
Heavy Atom Count: 6
Formal Charge: 0
Complexity: 46.8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Boiling Point: 268-270 ℃
Melting Point: 101-105 ℃
Flash Point: 157ºC
Purity: > 98.0 % (GC)
Density: 1.142 g/cm3
Appearance: Colorless crystals.
Storage: Store at RT.
HS Code: 29241900
Log P: 0.32700
MDL: MFCD00008286
PSA: 41.13
Refractive Index: 1.413
Risk Statements: R62

RTECS: YS9868000
Safety Statements: S24/25
Stability: Stable under normal temperatures and pressures.
SYNONYMS: N,N′-Dimethylurea
CAS NUMBER: 96-31-1
MOLECULAR WEIGHT: 88.11
BEILSTEIN REGISTRY NUMBER: 1740672
EC NUMBER: 202-498-7
MDL NUMBER: MFCD00008286
Auto Ignition: 400 °C (DIN 51794) (Lit.)
Base Catalog Number: 15784780
Beilstein Registry Number: 1740672
Boiling Point: 262 °C (Lit.)
CAS #: 96-31-1
Density: 1.14 g/cm3 at 20 °C (Lit.)

EC Number: 202-498-7
Flash Point: > 157 °C (Lit.)
Melting Point: 100 - 110 °C
Molecular Formula: C3H8N2O
Molecular Weight: 88.11
pH: 9.0 - 9.5 (100 g/L, H2O, 20 °C) (Lit.)
Purity: ≥98%
RTECS Number: YS9868000
Solubility: Soluble in ethanol (200 mg in 4 mL).
Melting Point: 105°C
Boiling Point: 270°C
Color: White
Formula Weight: 88.11
Physical Form: Crystal-Powder at 20°C
Chemical Name or Material: 1,3-Dimethylurea
CAS: 96-31-1

EINECS: 202-498-7
InChI: InChI=1/C3H8N2O/c1-4-3(6)5-2/h1-2H3,(H2,4,5,6)
InChIKey: MGJKQDOBUOMPEZ-UHFFFAOYSA-N
Molecular Formula: C3H8N2O
Molar Mass: 88.11
Density: 1.142
Melting Point: 101-104°C (lit.)
Boiling Point: 268-270°C (lit.)
Flash Point: 157 °C
Water Solubility: 765 g/L (21.5 ºC)
Solubility: Soluble in water, ethanol, acetone, benzene, and ethyl acetate, etc.,
insoluble in ether and gasoline.
Vapor Pressure: 6 hPa (115 °C)
Appearance: Crystallization
Color: White

BRN: 1740672
pKa: 14.57±0.46 (Predicted)
pH: 9.0-9.5 (100g/l, H2O, 20℃)
Storage Condition: Store below +30°C.
Refractive Index: 1.4715 (estimate)
MDL: MFCD00008286
Melting Point: 100°C to 104°C
Density: 1.14
Boiling Point: 268°C to 270°C (decomposition)
Flash Point: 157°C (314°F)
Quantity: 250 g
Beilstein: 1740672
Formula Weight: 88.11
Percent Purity: 98%

Chemical Name or Material: N,N'-Dimethylurea
Chemical formula: CH₃NHCONHCH₃
Molar Mass: 88.11 g/mol
HS Code: 2924 19 00
Boiling point: 268 - 270 °C (1013 hPa)
Density: 1.14 g/cm3 (20 °C)
Flash point: 157 °C DIN 51758
Ignition temperature: 400 °C
Melting Point: 101 - 104 °C
pH value: 9.0 - 9.5 (H₂O)
Vapor pressure: <0.1 hPa (20 °C)
Bulk density: 500 kg/m3
Solubility: 765 g/l

Chemical Name: N,N’-dimethylurea
CAS No.: 96-31-1
Molecular Formula: C3H8N2O
Molecular Weight: 88.10840
PSA: 41.13000
LogP: 0.32700
Appearance & Physical State: white flake
Density: 1.142
Boiling Point: 268-270ºC
Melting Point: 101-105ºC
Flash Point: 157ºC
Refractive Index: 1.413
Water Solubility: 765 g/L (21.5 ºC)

Stability: Stable under normal temperatures and pressures.
Storage Condition: Store at RT.
Melting point: 101-104 °C(lit.)
Boiling point: 268-270 °C(lit.)
Density: 1.142
vapor pressure: 6 hPa (115 °C)
refractive index: 1.4715 (estimate)
Flash point: 157 °C
storage temp.: Store below +30°C.
solubility: H2O: 0.1 g/mL, clear, colorless

pka: 14.57±0.46(Predicted)
form: Crystals
color: White
PH: 9.0-9.5 (100g/l, H2O, 20℃)
Water Solubility: 765 g/L (21.5 ºC)
BRN: 1740672
InChIKey: MGJKQDOBUOMPEZ-UHFFFAOYSA-N
LogP: -0.783 at 25℃
CAS DataBase Reference: 96-31-1(CAS DataBase Reference)
FDA UNII: WAM6DR9I4X
NIST Chemistry Reference: Urea, N,N'-dimethyl-(96-31-1)
EPA Substance Registry System: 1,3-Dimethylurea (96-31-1)

CAS No.: 96-31-1
Molecular Formula: C3H8N2O
InChIKeys: InChIKey=MGJKQDOBUOMPEZ-UHFFFAOYSA-N
Molecular Weight: 88.11
Exact Mass: 88.11
EC Number: 202-498-7
UNII: WAM6DR9I4X
ICSC Number: 1745
NSC Number: 24823|14910
DSSTox ID: DTXSID5025156
Color/Form: RHOMBIC BIPYRAMIDAL CRYSTALS FROM CHLOROFORM-ETHER|COLORLESS PRISMS
HScode: 2924199090

PSA: 41.1
XLogP3: -0.5
Appearance: N,n'-dimethylurea appears as colorless crystals. (NTP, 1992)
Density: 1.142 g/cm3
Melting Point: 108 °C
Boiling Point: 268-270 °C
Flash Point: 154°C
Refractive Index: 1.414
Water Solubility: H2O: 765 g/L (21.5 ºC)
Vapor Pressure: Vapour pressure, Pa at 20°C: 0.042
Air and Water Reactions: Water soluble.
Reactive Group: Amides and Imides

Autoignition Temperature: 400 °C
Molecular Formula / Molecular Weight: C3H8N2O = 88.11
Physical State (20 deg.C): Solid
CAS RN: 96-31-1
Reaxys Registry Number: 1740672
PubChem Substance ID: 87566985
SDBS (AIST Spectral DB): 2161
MDL Number: MFCD00008286
Appearance: colorless crystals (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 108.00 °C. @ 760.00 mm Hg
Boiling Point: 269.00 °C. @ 760.00 mm Hg

Vapor Pressure: 0.547000 mmHg (est)
Flash Point: 116.00 °F. TCC ( 46.60 °C. ) (est)
logP (o/w): -0.490
Soluble in: water, 1.615e+004 mg/L @ 25 °C (est)
Synonyms: N,N'-Dimethylurea
Molecular Formula: C3H8N2O
Molecular Weight: 88.11
CAS Number: 96-31-1
EINECS: 202-498-7
Appearance: White powder
Density: 1.142
Melting Point: 101-105 ºC
Stability: Stable under ordinary conditions.
Appearance: White powder
PH value: 6.5-8.0

Assay: ≥97.5%
Water: ≤0.5
Density: 0.9±0.1 g/cm3
Boiling Point: 269.0±0.0 °C at 760 mmHg
Melting Point: 101-104 °C(lit.)
Molecular Formula: C3H8N2O
Molecular Weight: 88.108
Flash Point: 124.3±18.9 °C
Exact Mass: 88.063660
PSA: 41.13000
LogP: -1.01
Vapour Pressure: 0.0±0.5 mmHg at 25°C
Index of Refraction: 1.414
Storage condition: Store at RT.
Water Solubility: 765 g/L (21.5 ºC)
Synonyms: 1,3-dimethylurea



FIRST AID MEASURES of N,N'-DIMETHYLUREA:
-Description of first-aid measures:
*General advice:
Consult a physician.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of N,N'-DIMETHYLUREA:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Pick up and arrange disposal without creating dust.
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of N,N'-DIMETHYLUREA:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of N,N'-DIMETHYLUREA:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Choose body protection
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of N,N'-DIMETHYLUREA:
-Precautions for safe handling:
*Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage class:
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of N,N'-DIMETHYLUREA:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


N,N-DIMETHYLUREA (DMU)
N,N-Dimethylurea (DMU) is an organic chemical substance, CAS No.:96-31-1, molecular formula: C3H8N2O
N,N-Dimethylurea (DMU) is a colorless, volatile liquid with a penetrating odor.


CAS Number: 96-31-1
EC Number: 202-498-7
MDL number: MFCD00008286
Linear Formula: (CH3NH)2CO
Chemical formula: C3H8N2O



N,N′-Dimethylurea, DMU, 1,3-Dimethylurea, 1,3-DIMETHYLUREA, N,N'-Dimethylurea, 96-31-1, sym-Dimethylurea, Urea, N,N'-dimethyl-, Symmetric dimethylurea, Urea, 1,3-dimethyl-, N,N'-Dimethylharnstoff, 1,3-Dimethyl urea, NSC 14910, BRN 1740672, AI3-24386, MFCD00008286, WAM6DR9I4X, DMU, DTXSID5025156, CHEBI:80472, Urea,3-dimethyl-, Urea,N'-dimethyl-, NSC-14910, 1,3-Dimethylurea, 98%, WLN: 1MVM1, CCRIS 2509, HSDB 3423, EINECS 202-498-7, UNII-WAM6DR9I4X, Dimethylharnstoff, 1.3-Dimethylurea, N,N-Dimethyl-Urea, 1,3 dimethyl urea, N,N'-dimethyl urea, 1,1'-Dimethylurea, 1,3-Dimethylcarbamide, bmse000248, EC 202-498-7, UREA,1,3-DIMETHYL, (CH3NH)2CO, DIMETHYL UREA [INCI], DIMETHYLUREA, N,N'-, N,N'-Dimethylurea, ~98%, DTXCID605156, CHEMBL1234380, 1,3-DIMETHYLUREA [HSDB], NSC14910, NSC24823, Tox21_200794, 1,3-Dimethylurea;N,N'-Dimethylurea, NSC-24823, AKOS000120912, CS-W013749, PB47928, CAS-96-31-1, NCGC00248834-01, NCGC00258348-01, SY004507, N,N inverted exclamation mark -Dimethylurea, A4569, D0289, FT-0606700, EN300-20740, P17517, ethyl 5-oxo-2,3-diphenyl cyclopentanecarboxylate, A845576, N,N'-Dimethylurea, (sym.), >=99% (from N), Q419740, W-100145, N,N'-Dimethylurea, PESTANAL(R), analytical standard,
F0001-2292, N,N'-Dimethylurea, (sym.), >=95.0% (HPLC), technical, InChI=1/C3H8N2O/c1-4-3(6)5-2/h1-2H3,(H2,4,5,6), Urea, 1,3-dimethyl-, sym-Dimethylurea, N,N'-Dimethylurea, Symmetric dimethylurea, 1,3-Dimethylurea, (CH3NH)2CO, 1,1'-Dimethylurea, DMU, N,N' Dimethylharnstoff, NSC 14910, (CH3NH)2CO, 1,1'-Dimethylurea, 1,3-dimethylurea, DMU, N,N'-Dimethylharnstoff, N,N'-dimethylurea, NSC 14910, Symmetric dimethylurea, sym-Dimethylurea, urea, 1,3-dimethyl-,
syM,N,N'-DIMETHYLUREA, (CH3NH)2CO, AKOS B029718, 1.3-DiMethyl u, 1,3-dimethyl-ure, SYM-DIMETHYLUREA, 1,3-DIMETHYLUREA, n,n’-dimethyl-ure,Dimethylcarbamide
N,N'-Dimethyl urea, 1,3-Dimethylurea, N,N’-dimethyl-Urea, 1,3-dimethyl-ure, n,n’-dimethylharnstoff, n,n’-dimethylharnstoff (german), n,n’-dimethylurea, sym-dimethylurea, Urea, 1,3-dimethyl-, sym-Dimethylurea, N,N'-Dimethylurea, Symmetric dimethylurea, 1,3-Dimethylurea, (CH3NH)2CO, 1,1'-Dimethylurea, DMU, N,N'-Dimethylharnstoff, NSC 14910, Urea, N,N′-dimethyl-, Urea, 1,3-dimethyl-, N,N′-Dimethylurea, 1,3-Dimethylurea, Symmetric dimethylurea, sym-Dimethylurea,
NSC 14910, NSC 24823, Urea,1,3-dimethyl- (8CI), N,N'-Dimethylurea, NSC 14910, NSC 24823, Symmetric dimethylurea, sym-Dimethylurea, Urea,N,N’-dimethyl, UNII-WAM6DR9I4X, MeNHNCONHMe, sym-Dimethylurea, N,N`-Dimethylurea,



N,N-Dimethylurea (DMU) is a urea derivative and used as an intermediate in organic synthesis.
N,N-Dimethylurea (DMU) is a colorless crystalline powder with little toxicity.
N,N-Dimethylurea (DMU) is also used for synthesis of caffeine, pharmachemicals, textile aids, herbicides and other.


In the textile processing industry N,N-Dimethylurea (DMU) is used as intermediate for the production of formaldehyde-free easy-care finishing agents for textiles.
In the Swiss Product Register there are 38 products containing N,N-Dimethylurea (DMU), among them 17 products intended for consumer use.


Product types are e.g. paints and cleaning agents.
The content of N,N-Dimethylurea (DMU) in consumer products is up to 10 %.
Use in cosmetics has been proposed, but there is no information available as to N,N-Dimethylurea (DMU)'s actual use in such applications.


N,N-Dimethylurea (DMU) is a white crystals.
N,N-Dimethylurea (DMU) is a colorless, volatile liquid with a penetrating odor.
N,N-Dimethylurea (DMU) is soluble in water and alcohols and has a melting point of -3°C.


N,N-Dimethylurea (DMU) is a colorless powder, used as building block for active ingredients or intermediate for formaldehyde-free textile additives.
N,N-Dimethylurea (DMU) is a member of the class of ureas that is urea substituted by methyl groups at positions 1 and 3.
N,N-Dimethylurea (DMU) is water soluble.


N,N-Dimethylurea (DMU) is an organic compound that has been shown to bind to the carbonyl group of proteins and act as a hydrogen-bond donor.
The nitrogen atoms are coordinated to form two pyramidal structures with the hydrogen bonding between the nitrogen atoms.
This coordination geometry leads to a molecule that is planar and the frequency shift of IR spectroscopy data confirms this structure.


The reaction mechanism for N,N-Dimethylurea (DMU) begins with an attack by the oxygen atom on the carbon atom of tetramethylurea forming an intermediate called trimethylamine, which then reacts with trifluoroacetic acid (TFA) leading to the formation of N,N-Dimethylurea (DMU).
N,N-Dimethylurea (DMU) is a colorless crystals.


N,N-Dimethylurea (DMU) Market revolves around the production and distribution of the chemical compound 1,3-Dimethylurea, identified by the CAS (Chemical Abstracts Service) number 96–31–1.
N,N-Dimethylurea (DMU) is a derivative of urea and is characterized by its molecular structure, consisting of two methyl groups attached to the nitrogen atoms of the urea molecule.


N,N-Dimethylurea (DMU) Market plays a crucial role in the chemical industry, serving as a key intermediate in the synthesis of various chemicals, including pharmaceuticals and agrochemicals.
N,N-Dimethylurea (DMU) is utilized as a building block in the creation of complex molecules, contributing to advancements in drug development and agricultural formulations.


The growth of the N,N-Dimethylurea (DMU) Market is propelled by several key factors.
Primarily, the compound’s significance as an intermediate in the synthesis of pharmaceuticals drives its demand, as N,N-Dimethylurea (DMU) plays a crucial role in the development of diverse drug compounds.



USES and APPLICATIONS of N,N-DIMETHYLUREA (DMU):
N,N-Dimethylurea (DMU) (IUPAC systematic name: 1,3-Dimethylurea ) is a urea derivative and used as an intermediate in organic synthesis.
N,N-Dimethylurea (DMU) is with the progress of science and technology and the development of society, chemical products have invariably permeated our daily lives, in medicine, food, cosmetics, electronics, industry, and other areas, becoming an essential part of our lives.


One such N,N-Dimethylurea (DMU) is Salicylaldehyde which has developed particularly rapidly in recent years.
Pharmaceutical intermediates, N,N-Dimethylurea (DMU) is also used in the production of fiber treatment agents.
In medicine, N,N-Dimethylurea (DMU) is used to synthesize theophylline, caffeine and nifedipine hydrochloride, etc.


The design, research, and development of pharmaceutical intermediates of N,N-Dimethylurea (DMU) including more than 330 kinds of pharmaceutical intermediates such as Anti-infectives, Cardiovascular and Cerebrovascular Systems, Digestive System, Santi-tumor, Nervous System, Geriatric Drugs, and Gynecological Drugs.


N,N-Dimethylurea (DMU) is used as a starting material to synthesize N,N′-dimethyl-6-amino uracil.
N,N-Dimethylurea (DMU) is used in combination with β-cyclodextrin derivatives, to form low melting mixtures (LMMs), which can be used as solvents for hydroformylation and Tsuji-Trost reactions.


N,N-Dimethylurea (DMU) is used to synthesize N,N′-disubstituted-4-aryl-3,4-dihydropyrimidinones via Biginelli condensation under solvent-free conditions.
N,N-Dimethylurea (DMU) is intermediate used in the production of and Agrochemical.
N,N-Dimethylurea (DMU) is used Agriculture, Urea-herbicide, Carbamate-herbicide, and Textile additives.


N,N-Dimethylurea (DMU) is used Formaldehyde-free textile additives, Cross linking agent for textiles made of cellulose fibers and their, synthetic mixtures, and Pharmaceuticals.
N,N-Dimethylurea (DMU) is used reagant for the synthesis of active ingredients, such as bronchodilators.


N,N-Dimethylurea (DMU) is used as a pharmaceutical drug to treat hyperammonemia.
N,N-Dimethylurea (DMU) is a urea derivative and used as an intermediate in organic synthesis.
N,N-Dimethylurea (DMU) is a colorless crystalline powder with little toxicity.


N,N-Dimethylurea (DMU) is also used for synthesis of caffeine, pharmachemicals, textile aids, herbicides and other.
In the textile processing industry N,N-Dimethylurea (DMU) is used as intermediate for the production of formaldehyde-free easy-care finishing agents for textiles.


N,N-Dimethylurea (DMU) is used pharmaceutical intermediates, also used in the production of fiber treatment agent.
N,N-Dimethylurea (DMU) is used in medicine to synthesize theophylline, caffeine and nificaran hydrochloride.
N,N-Dimethylurea (DMU) is used intermediate used in the production of Pharmaceuticals and Agrochemical.


Additionally, N,N-Dimethylurea (DMU) finds applications in agrochemicals, contributing to the synthesis of pesticides and herbicides.
The market benefits from the growth in these end-use industries, reflecting the compound’s versatility and importance in the production of high-value chemical products.


As pharmaceutical and agrochemical sectors continue to expand, the N,N-Dimethylurea (DMU) Market remains integral to supporting innovations and advancements within the broader chemical industry.”



PURIFICATION METHODS OF N,N-DIMETHYLUREA (DMU):
Crystallise the urea from acetone/diethyl ether by cooling in an ice bath.
Also crystallise N,N-Dimethylurea (DMU) from EtOH and dry it at 50o/5mm for 24hours.



REACTIVITY PROFILE OF N,N-DIMETHYLUREA (DMU):
N,N-Dimethylurea (DMU) is an amide.
Amides/imides react with azo and diazo compounds to generate toxic gases.
Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents.

Amides are very weak bases (weaker than water).
Imides are less basic yet and in fact react with strong bases to form salts.
That is, they can react as acids.

Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile.
The combustion of these compounds generates mixed oxides of nitrogen (NOx).



PHYSICAL and CHEMICAL PROPERTIES of N,N-DIMETHYLUREA (DMU):
Chemical formula: C3H8N2O
Molar mass: 88.110 g·mol−1
Appearance: Colorless, waxy crystals
Odor: Odorless
Density: 1.142 g mL−1
Melting point: 104.4 °C; 219.8 °F; 377.5 K
Boiling point: 269.1 °C; 516.3 °F; 542.2 K
Solubility in water: 765 g L−1
Magnetic susceptibility (χ): -55.1·10−6 cm3/mol
Thermochemistry:
Std enthalpy of formation (ΔfH⦵298): −312.1–−312.1 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): −2.0145–−2.0089 MJ mol−1
Molecular Weight: 88.11 g/mol

XLogP3: -0.5
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 0
Exact Mass: 88.063662883 g/mol
Monoisotopic Mass: 88.063662883 g/mol
Topological Polar Surface Area: 41.1Ų
Heavy Atom Count: 6
Formal Charge: 0
Complexity: 46.8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Physical state: flakes
Color: colorless
Odor: amine-like
Melting point/freezing point:
Melting point/range: 103 - 106 °C
Initial boiling point and boiling range: 268 - 270 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 157 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 9,0 - 9,5
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 765 g/l at 21,5 °C - soluble

Partition coefficient:
n-octanol/water: log Pow: -0,783
Vapor pressure: No data available
Density: 1,14 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Bulk density 0,50 g/l
Molecular Formula: CH3NHCONHCH3
CAS No: 96-31-1
EINECS: 202-498-7
Molecular Weight: 88.11
Appearance: White Crystals
Assay: ≥ 95%

Freezing point: 103'C Min
Volatile Content: ≤ 0.2%
Melting point: 104'C
CAS number: 96-31-1
EC number: 202-498-7
Hill Formula: C₃H₈N₂O
Chemical formula: CH₃NHCONHCH₃
Molar Mass: 88.11 g/mol
HS Code: 2924 19 00
Boiling point: 268 - 270 °C (1013 hPa)
Density: 1.14 g/cm3 (20 °C)
Flash point: 157 °C DIN 51758
Ignition temperature: 400 °C
Melting Point: 101 - 104 °C
pH value: 9.0 - 9.5 (H₂O)
Vapor pressure: Bulk density: 500 kg/m3
Solubility: 765 g/l

Chemical Name: N,N’-dimethylurea
CAS No.: 96-31-1
Molecular Formula: C3H8N2O
Molecular Weight: 88.10840
PSA: 41.13000
LogP: 0.32700
Appearance & Physical State: white flake
Density: 1.142
Boiling Point: 268-270ºC
Melting Point: 101-105ºC
Flash Point: 157ºC
Refractive Index: 1.413
Water Solubility: 765 g/L (21.5 ºC)
Stability: Stable under normal temperatures and pressures.
Storage Condition: Store at RT.
Melting point: 101-104 °C(lit.)
Boiling point: 268-270 °C(lit.)
Density: 1.142

vapor pressure: 6 hPa (115 °C)
refractive index: 1.4715 (estimate)
Flash point: 157 °C
storage temp.: Store below +30°C.
solubility: H2O: 0.1 g/mL, clear, colorless
pka: 14.57±0.46(Predicted)
form: Crystals
color: White
PH: 9.0-9.5 (100g/l, H2O, 20℃)
Water Solubility: 765 g/L (21.5 ºC)
BRN: 1740672
InChIKey: MGJKQDOBUOMPEZ-UHFFFAOYSA-N
LogP: -0.783 at 25℃
CAS DataBase Reference: 96-31-1(CAS DataBase Reference)
FDA UNII: WAM6DR9I4X
NIST Chemistry Reference: Urea, N,N'-dimethyl-(96-31-1)
EPA Substance Registry System: 1,3-Dimethylurea (96-31-1)

CAS No.: 96-31-1
Molecular Formula: C3H8N2O
InChIKeys: InChIKey=MGJKQDOBUOMPEZ-UHFFFAOYSA-N
Molecular Weight: 88.11
Exact Mass: 88.11
EC Number: 202-498-7
UNII: WAM6DR9I4X
ICSC Number: 1745
NSC Number: 24823|14910
DSSTox ID: DTXSID5025156
Color/Form: RHOMBIC BIPYRAMIDAL CRYSTALS FROM CHLOROFORM-ETHER|COLORLESS PRISMS
HScode: 2924199090
PSA: 41.1
XLogP3: -0.5
Appearance: N,n'-dimethylurea appears as colorless crystals. (NTP, 1992)
Density: 1.142 g/cm3

Melting Point: 108 °C
Boiling Point: 268-270 °C
Flash Point: 154°C
Refractive Index: 1.414
Water Solubility: H2O: 765 g/L (21.5 ºC)
Vapor Pressure: Vapour pressure, Pa at 20°C: 0.042
Air and Water Reactions: Water soluble.
Reactive Group: Amides and Imides
Autoignition Temperature: 400 °C
Molecular Formula / Molecular Weight: C3H8N2O = 88.11
Physical State (20 deg.C): Solid
CAS RN: 96-31-1
Reaxys Registry Number: 1740672
PubChem Substance ID: 87566985
SDBS (AIST Spectral DB): 2161
MDL Number: MFCD00008286
Appearance: colorless crystals (est)
Assay: 95.00 to 100.00

Food Chemicals Codex Listed: No
Melting Point: 108.00 °C. @ 760.00 mm Hg
Boiling Point: 269.00 °C. @ 760.00 mm Hg
Vapor Pressure: 0.547000 mmHg (est)
Flash Point: 116.00 °F. TCC ( 46.60 °C. ) (est)
logP (o/w): -0.490
Soluble in: water, 1.615e+004 mg/L @ 25 °C (est)
Synonyms: N,N'-Dimethylurea
Molecular Formula: C3H8N2O
Molecular Weight: 88.11
CAS Number: 96-31-1
EINECS: 202-498-7
Appearance: White powder
Density: 1.142
Melting Point: 101-105 ºC
Stability: Stable under ordinary conditions.
Appearance: White powder
PH value: 6.5-8.0

Assay: ≥97.5%
Water: ≤0.5
Density: 0.9±0.1 g/cm3
Boiling Point: 269.0±0.0 °C at 760 mmHg
Melting Point: 101-104 °C(lit.)
Molecular Formula: C3H8N2O
Molecular Weight: 88.108
Flash Point: 124.3±18.9 °C
Exact Mass: 88.063660
PSA: 41.13000
LogP: -1.01
Vapour Pressure: 0.0±0.5 mmHg at 25°C
Index of Refraction: 1.414
Storage condition: Store at RT.
Water Solubility: 765 g/L (21.5 ºC)
Synonyms: 1,3-dimethylurea
Molecular Weight: 88.11
Molecular Formula: C3H8N2O

Canonical SMILES: CNC(=O)NC
InChI: InChI=1S/C3H8N2O/c1-4-3(6)5-2/h1-2H3,(H2,4,5,6)
InChIKey: MGJKQDOBUOMPEZ-UHFFFAOYSA-N
Boiling Point: 268-270 ℃
Melting Point: 101-105 ℃
Flash Point: 157ºC
Purity: > 98.0 % (GC)
Density: 1.142 g/cm3
Appearance: Colorless crystals.
Storage: Store at RT.
HS Code: 29241900
Log P: 0.32700
MDL: MFCD00008286
PSA: 41.13
Refractive Index: 1.413
Risk Statements: R62
RTECS: YS9868000
Safety Statements: S24/25
Stability: Stable under normal temperatures and pressures.



FIRST AID MEASURES of N,N-DIMETHYLUREA (DMU):
-Description of first-aid measures:
*General advice:
Consult a physician.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of N,N-DIMETHYLUREA (DMU):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Pick up and arrange disposal without creating dust.
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of N,N-DIMETHYLUREA (DMU):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of N,N-DIMETHYLUREA (DMU):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Choose body protection
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of N,N-DIMETHYLUREA (DMU):
-Precautions for safe handling:
*Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage class:
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of N,N-DIMETHYLUREA (DMU):
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



N,N-DIMETILETANOLAMIN
2,2'-{1,2-Propandiylbis[nitrilo(Z)methylyliden]}diphenol; 2,2'-{1,2-Propanediylbis[nitrilo(Z)methylylidene]}diphenol; 2,2'-{1,2-Propanediylbis[nitrilo(Z)méthylylidène]}diphénol; N,N'-bis(salicylidene)-1.2-propanediamine; N,N'-Disalicylidene-1,2-propanediamine; Phenol, 2,2'-[(1-methyl-1,2-ethanediyl)bis[nitrilo(Z)methylidyne]]bis- CAS NO:94-91-7
N,N-Diethylhydroxylamine (DEHA 85)
N-Ethyl-N-hydroxy-Ethanamine; N,N-Diethylhydroxylamine; DEHA CAS NO:3710-84-7
N,N-Diethylhydroxylamine 85 % (DEHA 85)
N N Dimethyl amine; Dimetilamin; dimetil amin; N,N-Dimethylamine; N-methylmethanamine; N,N, DMA; Dimethylamine; CAS NO: 124-40-3
N,N'-METHYLENE-BIS-ACRYLAMIDE
N,N'-Methylene-bis-acrylamide is the organic compound with the formula (H2C=CHCONH)2CH2.
N,N'-Methylene-bis-acrylamide is a raw material of photosensitive nylon or photosensitive plastic.
N,N'-Methylene-bis-acrylamide is a white crystalline powder with a neutral odor.



CAS Number: 110-26-9
EC Number: 203-750-9
MDL number: MFCD00008625
Linear Formula: (H2C=CHCONH)2CH2
Chemical formula: C7H10N2O2




Bis-acrylamide, N,N-Methylene-bis-acrylamide, N,N'-METHYLENEBISACRYLAMIDE, 110-26-9, N,N'-Methylenediacrylamide, N,N'-Methylene-bis-acrylamide, Methylenebisacrylamide, Bis-acrylamide, Methylenediacrylamide, n,n-methylenebisacrylamide, N,N'-Methylenebis(acrylamide), Bisacrylamide,
2-Propenamide, N,N'-methylenebis-, N-[(prop-2-enoylamino)methyl]prop-2-enamide, N,N'-Methylidenebisacrylamide, Acrylamide, N,N'-methylenebis-, N,N'-Methylenebis(2-propenamide), NSC 406836, MBAA, N-[(prop-2-enamido)methyl]prop-2-enamide, EDK4RIE19C, N,N'-methylene bisacrylamide, MLS001055454, DTXSID8025595, MFCD00008625, NSC-406836, Bisacrylamide, MBA, Methylenebisacrylamide NCGC00090721-03, SMR001227199, Acrylamide,N'-methylenebis-, N,N'-Methylenebis[acrylamide], 2-Propenamide,N'-methylenebis-, bis acrylamide, CCRIS 4672, EINECS 203-750-9, UNII-EDK4RIE19C, N-((PROP-2-ENOYLAMINO)METHYL)PROP-2-ENAMIDE, BRN 1706297, AI3-08643, NAPP, Methylenebis[acrylamide], cid_8041, n,n'-methylenebis acrylamide, n,n'-methylenebis-acrylamide, SCHEMBL20000, N-(acrylamidomethyl)acrylamide, N,N' methylene bis acrylamide, N,N`-Methylene-bis-acrylamide, DTXCID205595, N,N'-Diacryloylmethylenediamine, CHEMBL1401480, N,N'-Methylidenebis[acrylamide], BDBM74235, NSC7774, HY-D0848, N,N'-Methylenebis-Acrylamide, 2%, NSC-7774, Tox21_400038, NSC406836, AKOS005206740, AKOS025264600, N,N'-Methylenebis(acrylamide), 99%, N-[(Acryloylamino)methyl]acrylamide, METHYLENEBIS-ACRYLAMIDE, N,N'-, NCGC00090721-01, NCGC00090721-02, NCGC00090721-04, CAS-110-26-9, NCI60_041713, N,N'-METHYLENEBISACRYLAMIDE [INCI], N,N'-Methylenebisacrylamide, N,N'-Methylenebis(acrylamide), BB 0295285,
CS-0014818, CS-0202692, FT-0629399, M0506, M2877, E80374, EN300-104853, A905227, N-[(1-oxoprop-2-enylamino)methyl]-2-propenamide, Q3869308, W-108692, 26949-19-9, N,N'-Methylenebisacrylamide, bis-Acrylamide, Methylenebisacrylamide, N,N'-Methylenediacrylamide, BIS, MBA, BIS, METHYLENEBISACRYLAMIDE, N,N-METHYLENE-BIS-ACRYLAMIDE, BISACRYLAMIDE, napp, N,N-Methylenebisa, BIS MBA, N,N'-MethyL, enebisacryL, N,N'-MethyL, enebisacryL, N,N-Methylenebisa, Bis or Bis Acrylamide, N,N-Methylenebisacrylamide, N,N'-Methylenebisacrylamide, N,N'-Methylene bisacrylamide, N,N'-Diacryloylmethylenediamine, N,N'-Methylene-bis-(acrylamide), N,N'-Methylidenebis[acrylamide], N-[(Acryloylamino)methyl]acrylamide, N,N'-methylene-bis(acrylamide), N,N'-methylenebis-2-propenamide, Methylene bisacrylamide, N,N'-methylenebisacrylamide, N-{[(1-hydroxyprop-2-en-1-ylidene)amino]methyl}prop-2-enimidate, N,N'-METHYLENESBISACRYLAMIDE, N,N'-METHYLENEDIACRYLAMIDE, N,N'-METHYLENEBIS(ACRYLAMIDE)-HG, n,n'-methylenebis(2-propenamide), N, N-METHYLENE-BIS-ACRYLAMIDE, N,N'-METHYLENEBISACRYLAMIDE



N,N'-Methylene-bis-acrylamide is the organic compound with the formula (H2C=CHCONH)2CH2.
A colorless solid, N,N'-Methylene-bis-acrylamide is a crosslinking agent in polyacrylamides, e.g., as used for SDS-PAGE.
N,N'-Methylene-bis-acrylamide is a cross linking agent that polymerizes with acrylamide and creates cross links within the polyacrylamide gel.


N,N'-Methylene-bis-acrylamide is capable of creating a network rather than linear chains which helps in maintaining the firmness of gel.
N,N'-Methylene-bis-acrylamide is a cross-linker reagent used for precise, critical PAGE gels.
N,N'-Methylene-bis-acrylamide can react with acrylamide to produce breakdown fluid or react with monomer to produce insoluble resin.


N,N'-Methylene-bis-acrylamide is a white crystalline powder.
N,N'-Methylene-bis-acrylamide is white crystalline powder with a neutral odor.
N,N'-Methylene-bis-acrylamide is very slightly water soluble.


N,N'-Methylene-bis-acrylamide is soluble in water or methanol.
N,N'-Methylene-bis-acrylamide is soluble in water, ethanol and methanol.
N,N'-Methylene-bis-acrylamide is a white or light yellow powder crystals.


N,N'-Methylene-bis-acrylamide's melting point is 184 ℃ and (decomposition), relative density 1. 352 (30 ℃).
N,N'-Methylene-bis-acrylamide is soluble in water, but also soluble in ethanol, acetone and other organic solvents.
N,N'-Methylene-bis-acrylamide is a cross linking agent that readily polymerizes with acrylamide to create cross links within the polyacrylamide gel matrix.


N,N'-Methylene-bis-acrylamide effectively creates a network rather than linear chains, a property that helps in maintaining the firmness of gel.
N,N'-Methylene-bis-acrylamide belongs to the class of organic compounds known as acrylic acids and derivatives.
These are organic compounds containing acrylic acid CH2=CHCO2H or a derivative thereof.


Based on a literature review a significant number of articles have been published on N,N'-Methylene-bis-acrylamide.
N,N'-Methylene-bis-acrylamide has been identified in human blood as reported by (PMID: 31557052 ).
N,N'-Methylene-bis-acrylamide is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives.


N,N'-Methylene-bis-acrylamide is part of the human exposome.
N,N'-Methylene-bis-acrylamide is a cross linking agent that polymerizes with acrylamide and creates cross links within the polyacrylamide gel.
N,N'-Methylene-bis-acrylamide is capable of creating a network rather than linear chains which helps in maintaining the firmness of gel.


N,N'-Methylene-bis-acrylamide is a preparatory agent for polyacrylamide gels
The thickener for all water phase pigment printing is produced by copolymerization of N,N'-Methylene-bis-acrylamide with acrylamide and butyl acrylate, which is the key auxiliary for implementing the new process of all water phase pigment printing.


N,N'-Methylene-bis-acrylamide is a cross-linking agent used during the formation of polymers such as polyacrylamide.
N,N'-Methylene-bis-acrylamide's molecular formula is C7H10N2O2.
N,N'-Methylene-bis-acrylamide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.


N,N'-Methylene-bis-acrylamide is white crystalline powder, soluble in water, soluble in ethanol, acetone and other organic solvents.
N,N'-Methylene-bis-acrylamide is a cross-linking agent used during the formation of polymers such as polyacrylamide.
N,N'-Methylene-bis-acrylamide's molecular formula is C7H10N2O2.


Bisacrylamide is used in biochemistry as N,N'-Methylene-bis-acrylamide is one of the compounds of the polyacrylamide gel (used for SDS-PAGE).
Bisacrylamide polymerizes with acrylamide and is capable of creating cross-links between polyacrylamide chains, thus creating a network of polyacrylamide rather than unconnected linear chains of polyacrylamide.


N,N'-Methylene-bis-acrylamide can be production of water-based fracturing fluid in the process of oilfield production process.
N,N'-Methylene-bis-acrylamide can be used in the pharmaceutical gel explosive, has a good stability and strong degree is big, good water resistance.
N,N'-Methylene-bis-acrylamide is the key to the implementation of total aqueous pigment printing process additives.


N,N'-Methylene-bis-acrylamide is available for high content of organic matter in water treatment decolorization, purification of the refined sugar and organic compounds, waste water treatment, to the heat source (removal rate 88%), the extraction of antibiotics streptomycin (300000 V/ml) adsorption styrene hydrochloride.


N,N'-Methylene-bis-acrylamide is used in water conservancy, power engineering, underground engineering, civil air defense engineering, tunnel engineering construction have stable foundation role, make the effect is very good, reliable quality of waterproof plugging grouting material.
N,N'-Methylene-bis-acrylamide is a cross linking agent that polymerizes with acrylamide and creates cross links within the polyacrylamide gel.
N,N'-Methylene-bis-acrylamide is capable of creating a network rather than linear chains which helps in maintaining the firmness of gel.



USES and APPLICATIONS of N,N'-METHYLENE-BIS-ACRYLAMIDE:
N,N'-Methylene-bis-acrylamide can be copolymerized with acrylamide to produce oilfield fracturing fluid, and copolymerized with a certain monomer to produce insoluble resin.
N,N'-Methylene-bis-acrylamide can be used as a water plugging grouting material or as a crosslinking agent.


N,N'-Methylene-bis-acrylamide is used in the production of printing and dyeing additives, napkins, health diapers, and other industrial absorbent resins.
N,N'-Methylene-bis-acrylamide is used Separation of biopolymer compounds (proteins, peptides, nucleic acids).
N,N'-Methylene-bis-acrylamide is used the crosslinking agent of polyacrylamide gel was prepared.


N,N'-Methylene-bis-acrylamide is used Polyacrylamide gel technology and clinical test.
N,N'-Methylene-bis-acrylamide is also widely used in electronics, papermaking, printing plate making, synthetic resin modification, coatings, adhesives, and other fields.


Cross-linking agent for preparation of polyacrylamide.
In underground buildings, the insoluble gel formed by AM and N,N'-Methylene-bis-acrylamide injected into the soil layer strengthens the soil layer to prevent water seepage.


Adding concrete can shorten the curing period of concrete and improve its water resistance.
N,N'-Methylene-bis-acrylamide is used organic intermediate, cross-linking agent.
N,N'-Methylene-bis-acrylamide also can be used as crosslink agent.


N,N'-Methylene-bis-acrylamide also can be used in auxiliary, table cloth, health care diaper and AQ.
N,N'-Methylene-bis-acrylamide is the material to separate the amino acid and the material of photosensitive nylon and plastic.
N,N'-Methylene-bis-acrylamide can be used as insoluble gel to reinforce the earth layer or added into the concrete to reduce the maintenance time and improve the resistance to water.


Moreover, N,N'-Methylene-bis-acrylamide also can be used in electronics, papermaking, printing, resin, coating and adhesive.
N,N'-Methylene-bis-acrylamide may be used in UV scanning gels.
N,N'-Methylene-bis-acrylamide should mixed with acrylamide for making polyacrylamide gels for use in protein and nucleic acid electrophoresis.


N,N'-Methylene-bis-acrylamide is an organic intermediate; cross-linking agent for preparation of polyacrylamides; in preparing poly-acrylamide gel for e1ectrophoresis, chemical grouting and other purposes; in NAPP and Nyloprint UV-cured printing plates.


N,N'-Methylene-bis-acrylamide is used as photosensitive nylon and photosensitive plastic raw materials, building grouting materials, also used in photography, printing, plate making, etc;
N,N'-Methylene-bis-acrylamide can be used as an efficient crosslinking agent in the polymerization of acrylic acid and acrylamide.


N,N'-Methylene-bis-acrylamide is an oil field fracturing fluid, super absorbent resin, water plugging agent, concrete additive, alcohol soluble photosensitive nylon resin, paper??
N,N'-Methylene-bis-acrylamide is an important additive in the synthesis of strong agent and water treatment flocculant.


N,N'-Methylene-bis-acrylamide and acrylamide copolymer can be made into oil field fracturing fluid, and a monomer copolymerization to prepare insoluble resin, can be used as water plugging grouting material.
N,N'-Methylene-bis-acrylamide can also be used as a cross-linking agent.


The application of photosensitive materials, water-absorbing materials, optical fiber cable coating and biotechnology is being developed abroad, but the application in this field in China needs to be further developed.
In addition, N,N'-Methylene-bis-acrylamide is also used in medical, cosmetics, paper processing, coatings, adhesives and other aspects.


N,N'-Methylene-bis-acrylamide is used as an intermediate and cross-linking agent utilized in the preparation of polymers like polyacrylamide.
N,N'-Methylene-bis-acrylamide is also used in biochemistry for the preparation of polyacrylamide gels, which is useful for the electrophoretic separation of nucleic acids and proteins.


Further, N,N'-Methylene-bis-acrylamide is employed in the synthesis of acrylic resin and adhesives.
In addition to this, N,N'-Methylene-bis-acrylamide is used as a plugging agent in oilfield drilling and construction grouting.
N,N'-Methylene-bis-acrylamide is used as an intermediate and cross-linking agent utilized in the preparation of polymers like polyacrylamide.


N,N'-Methylene-bis-acrylamide is also used in biochemistry for the preparation of polyacrylamide gels, which is useful for the electrophoretic separation of nucleic acids and proteins.
Further, N,N'-Methylene-bis-acrylamide is employed in the synthesis of acrylic resin and adhesives.


N,N'-Methylene-bis-acrylamide is used as an organic intermediate, cross-linking agent, for making polyacrylamides, and for preparing polyacrylamide gel for electrophoresis, chemical grouting, and other uses.
N,N'-Methylene-bis-acrylamide is used in the preparation of polyacrylamide gels for electrophoretic separation of nucleic acids and proteins.


N,N'-Methylene-bis-acrylamide has been used in gel preparation.
N,N'-Methylene-bis-acrylamide is used cross-linking agent for preparation of polyacrylamides.
N,N'-Methylene-bis-acrylamide can be used as water shutoff agent in oil field drilling operation and construction grouting operation, as well as crosslinking agent in the synthesis of acrylic resin and adhesives.


N,N'-Methylene-bis-acrylamide can be used as raw material of photosensitive nylon and photosensitive plastics, building grouting material, photography, printing, plate making, etc.
A cross-linking agent, N,N'-Methylene-bis-acrylamide is used in the formation of polymers, such as polyacrylamide.


N,N'-Methylene-bis-acrylamide therefore has an important role in gel electrophoresis (SDS-PAGE).
N,N'-Methylene-bis-acrylamide is used in the production of super absorbent resin.
Superabsorbent resin can be used to produce sanitary products with excellent water absorption.


N,N'-Methylene-bis-acrylamide can also be used in the production of agricultural water retaining agent.
N,N'-Methylene-bis-acrylamide is used in biochemistry as it is one of the compounds of the polyacrylamide gel.
A cross-linking agent, N,N'-Methylene-bis-acrylamide is used in the formation of polymers, such as polyacrylamide.
N,N'-Methylene-bis-acrylamide therefore has an important role in gel electrophoresis



SYNTHESIS OF N,N'-METHYLENE-BIS-ACRYLAMIDE:
Acrylamide reacts with an aqueous solution of formaldehyde in the presence of copper(I) chloride as a polymerization inhibitor and sulfuric acid as catalyst to form N,N'-Methylene-bis-acrylamide with yields of 60 to 80%.
The reaction proceeds via N-hydroxymethylacrylamide, which can be detected in alkaline solution and decomposes in acid to give N,N'-Methylene-bis-acrylamide.

Using acrylamide and paraformaldehyde in 1,2-dichloroethane gives a clear solution upon heating, from which MBA crystallizes.
In aqueous media, acrylonitrile also reacts with formaldehyde to give crude N,N'-Methylene-bis-acrylamide, which can be purified by recrystallization with acetone/water.

As a symmetric, unconjugated divinyl monomer, N,N'-Methylene-bis-acrylamide can be used with suitable initiators in cyclopolymerizations to create linear, soluble polymers whose backbones are built from five- and seven-membered rings.
With acrylic and vinylic monomers such as acrylonitrile, acrylamide, and substituted acrylamides, N,N'-Methylene-bis-acrylamide can undergo radical copolymerization to form highly crosslinked gels, using peroxides, UV light, or redox initiators.

The properties of such gels are determined by the crosslink density, and targeted gel formation using N,N'-Methylene-bis-acrylamide crosslinking gives useful technical properties used in various applications, such as in adhesives, paints, and superabsorbent.
In biochemistry, N,N'-Methylene-bis-acrylamide is used for chromatography gels and polyacrylamide gel electrophoresis.



REACTIONS AND USES OF N,N'-METHYLENE-BIS-ACRYLAMIDE:
Under basic conditions, N,N'-Methylene-bis-acrylamide reacts further with formaldehyde at the amide nitrogen to give N-hydroxymethyl,N,N′-methylenebisacrylamide.
Nucleophiles such as alcohols, amines, or thiols add across the activated vinyl groups, giving mixtures of mono- and disubstituted products.
As a bifunctional electron-poor dienophile, MBA reacts with electron-rich dienes, such as cyclopentadiene, in Diels–Alder reactions, giving the corresponding norbornene adducts.



REACTIVITY PROFILE OF N,N'-METHYLENE-BIS-ACRYLAMIDE:
N,N'-Methylene-bis-acrylamide is incompatible with strong oxidizers, strong acids and strong bases.



ALTERNATIVE PARENTS OF N,N'-METHYLENE-BIS-ACRYLAMIDE:
*Secondary carboxylic acid amides
*Organopnictogen compounds
*Organonitrogen compounds
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



PURIFICATION METHODS OF N,N'-METHYLENE-BIS-ACRYLAMIDE:
Recrystallise the amide from MeOH (100g dissolved in 500mL boiling MeOH) and filter without suction in a warmed funnel.
Allow to stand at room temperature and then at -15oC overnight.
The crystals are collected with suction in a cooled funnel and washed with cold MeOH.
The crystals are air-dried in a warm oven.



SUBSTITUENTS OF N,N'-METHYLENE-BIS-ACRYLAMIDE:
*Acrylic acid or derivatives
*Secondary carboxylic acid amide
*Carboxamide group
*Organic nitrogen compound
*Organic oxygen compound
*Organopnictogen compound
*Organic oxide
*Hydrocarbon derivative
*Organooxygen compound
*Organonitrogen compound
*Carbonyl group
*Aliphatic acyclic compound



PREPARATION METHOD OF N,N'-METHYLENE-BIS-ACRYLAMIDE:
Acrylonitrile method acrylonitrile and formaldehyde are hydrolyzed under the catalysis of sulfuric acid to generate methylene bisacrylamide sulfate, which is then neutralized by ammonia to precipitate methylene bisacrylamide crystals, and then washed and dried to obtain a finished product.
The acrylamide method produces N,N'-Methylene-bis-acrylamide by reacting acrylamide with formaldehyde in water or organic solvent under acidic catalysis, and then washing and drying to obtain a finished product.
N-methylol acrylamide method N,N'-Methylene-bis-acrylamide is produced from the reaction of N-methylol acrylamide and acrylamide under acidic conditions.



PHYSICAL and CHEMICAL PROPERTIES of N,N'-METHYLENE-BIS-ACRYLAMIDE:
Chemical formula: C7H10N2O2
Molar mass: 154.169 g·mol−1
Appearance: white solid
Melting point: 181–182 °C (358–360 °F; 454–455 K)
Physical state: powder
Color: white
Odor: characteristic odour
Melting point/freezing point:
Melting point/range: > 300 °C
Initial boiling point and boiling range: 333,8 °C at 1.013 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available

Water solubility: 34,1 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: -0,08 at 25 °C
Bioaccumulation is not expected.
Vapor pressure: < 0,01 hPa
Density: 1,216 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Surface tension 70 mN/m at 1g/l at 20 °C
Molecular Weight: 154.17 g/mol
XLogP3-AA: 0.1
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 4

Exact Mass: 154.074227566 g/mol
Monoisotopic Mass: 154.074227566 g/mol
Topological Polar Surface Area: 58.2Ų
Heavy Atom Count: 11
Formal Charge: 0
Complexity: 167
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
CAS number: 110-26-9
EC number: 203-750-9
Hill Formula: C₇H₁₀N₂O₂
Chemical formula: (CH₂CHCONH)₂CH₂
Molar Mass: 154.17 g/mol
HS Code: 2924 19 00

Density: 1.216 g/cm3 (20 °C)
Melting Point: 173.7 - 185.9 °C (decomposition)
pH value: >=5.0 (25 g/l, H₂O, 20 °C)
Vapor pressure: Bulk density: 200 kg/m3
form: powder
mp: >300 °C (lit.)
solubility water: soluble 20 g/L at 20 °C
storage temp.: 2-8°C
SMILES: string C=CC(=O)NCNC(=O)C=C
InChI: 1S/C7H10N2O2/c1-3-6(10)8-5-9-7(11)4-2/h3-4H,1-2,5H2,(H,8,10)(H,9,11)
InChI key: ZIUHHBKFKCYYJD-UHFFFAOYSA-N
CAS NUMBER: 110-26-9
MOLECULAR FORMULA: C7H10N2O2
MOLECULAR WEIGHT: 154.169 g/mol
BEILSTEIN REGISTRY NUMBER: 1706297
EC NUMBER: 203-750-9
MDL NUMBER: MFCD00008625

Melting point: >300 °C(lit.)
Boiling point: 277.52°C (rough estimate)
Density: 1.235
vapor density: 5.31 (vs air)
vapor pressure: 0-0.073Pa at 20-84.85℃
refractive index: 1.4880 (estimate)
storage temp.: 2-8°C
solubility: H2O: 20 mg/mL at 20 °C, clear, colorless
form: powder
pka: 13.07±0.46(Predicted)
color: White
PH: >=5.0 (25g/l, H2O, 20℃)
Odor: Odorless
PH Range: >5
Water Solubility: 0.01-0.1 g/100 mL at 18 ºC
Sensitive: Air & Light Sensitive
λmax: 528nm(H2O)(lit.)
BRN: 1706297
Stability: Light Sensitive

InChIKey: ZIUHHBKFKCYYJD-UHFFFAOYSA-N
LogP: -1.52--0.08 at 24-25℃ and pH4-10
Surface tension: 70.2-70.3mN/m at 1g/L and 20℃
Indirect Additives used in Food Contact Substances: N,N'-METHYLENEBIS(ACRYLAMIDE)
FDA 21 CFR: 175.105
CAS DataBase Reference: 110-26-9(CAS DataBase Reference)
EWG's Food Scores: 1
FDA UNII: EDK4RIE19C
NIST Chemistry Reference: 2-Propenamide, n,n'-methylenebis-(110-26-9)
EPA Substance Registry System: N,N'-Methylenebisacrylamide (110-26-9)
CAS: 110-26-9
EINECS: 203-750-9
InChI: InChI=1/C7H10N2O2/c1-4(6(8)10)3-5(2)7(9)11/h1-3H2,(H2,8,10)(H2,9,11)
InChIKey: ZIUHHBKFKCYYJD-UHFFFAOYSA-N
Molecular Formula: C7H10N2O2
Molar Mass: 154.17
Density: 1.235
Melting Point: >300°C(lit.)
Boling Point: 277.52°C (rough estimate)
Flash Point: 245.1°C

Water Solubility: 0.01-0.1 g/100 mL at 18 ºC
Solubility: H2O: 20mg/mL at20°C, clear, colorless
Vapor Presure: 0-0.073Pa at 20-84.85℃
Vapor Density: 5.31 (vs air)
Appearance: White crystal
Color: White
Odor: Odorless
Maximum wavelength(λmax): ['528nm(H2O)(lit.)']
BRN: 1706297
pKa: 13.07±0.46(Predicted)
PH: >=5.0 (25g/l, H2O, 20℃)
Storage Condition: 2-8°C
Sensitive: Air & Light Sensitive
Refractive Index: 1.4880 (estimate)
MDL: MFCD00008625
Chemical Formula: C7H10N2O2
Average Molecular Weight: 154.169
Monoisotopic Molecular Weight: 154.07422757
IUPAC Name: N-{[(1-hydroxyprop-2-en-1-ylidene)amino]methyl}prop-2-enimidic acid

Traditional Name: N-{[(1-hydroxyprop-2-en-1-ylidene)amino]methyl}prop-2-enimidic acid
CAS Registry Number: Not Available
SMILES: OC(C=C)=NCN=C(O)C=C
InChI Identifier: InChI=1S/C7H10N2O2/c1-3-6(10)8-5-9-7(11)4-2/h3-4H,1-2,5H2,(H,8,10)(H,9,11)
InChI Key: ZIUHHBKFKCYYJD-UHFFFAOYSA-N
Density: 1.1±0.1 g/cm3
Boiling Point: 445.1±41.0 °C at 760 mmHg
Melting Point: >300 °C(lit.)
Molecular Formula: C7H10N2O2
Molecular Weight: 154.167
Flash Point: 215.0±27.8 °C
Exact Mass: 154.074234
PSA: 58.20000
LogP: -1.44
Vapour density: 5.31 (vs air)
Vapour Pressure: 0.0±1.1 mmHg at 25°C
Index of Refraction: 1.475
Storage condition: 2-8°C
Water Solubility: 0.01-0.1 g/100 mL at 18 ºC



FIRST AID MEASURES of N,N'-METHYLENE-BIS-ACRYLAMIDE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of N,N'-METHYLENE-BIS-ACRYLAMIDE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of N,N'-METHYLENE-BIS-ACRYLAMIDE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of N,N'-METHYLENE-BIS-ACRYLAMIDE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of N,N'-METHYLENE-BIS-ACRYLAMIDE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
*Storage stability:
Recommended storage temperature: 2 - 8 °C
Air and light sensitive.



STABILITY and REACTIVITY of N,N'-METHYLENE-BIS-ACRYLAMIDE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
no information available


N,N'-METHYLENEBISMORPHOLINE
N,N'-Methylenebismorpholine is colorless liquid, soluble in water.
N,N’-Methylenebismorpholine is a highly concentrated industrial bactericide based on tetrahydrooxazines.
N,N’-Methylenebismorpholine is effective against gram-negative and gram positive bacterias.


CAS Number: 5625-90-1
EC Number: 227-062-3
MDL Number: MFCD00023369
Molecular Formula: C9H18N2O2


N,N'-Methylenebismorpholine is a low toxicity broad spectrum fungicide for water-based metalworking fluid.
N,N'-Methylenebismorpholine is soluble in water.
N,N’-Methylenebismorpholine, also known as dimethylformamide (DMF), is an organic compound belonging to the class of amides, and is one of the most widely used solvents in the world.


N,N’-Methylenebismorpholine is soluble in water.
N,N'-Methylenebismorpholine is a colorless, volatile liquid with a characteristic odor and a relatively low boiling point.
Owing to its good solubility N,N’-Methylenebismorpholine is suitable for oily as well as aqueous systems.


N,N’-Methylenebismorpholine is a highly concentrated industrial bactericide based on tetrahydrooxazines.
N,N'-Methylenebismorpholine, also known as dimethylformamide (DMF), is an organic compound belonging to the class of amides, and is one of the most widely used solvents in the world.



USES and APPLICATIONS of N,N'-METHYLENEBISMORPHOLINE:
N,N'-Methylenebismorpholine is used for Water Based Cutting Fluid.
N,N’-Methylenebismorpholine is employed as intermediate for pharmaceutical.
Compared to hexahydrotriazines and oxazolidines, N,N’-Methylenebismorpholine is more stable in metalworking concentrates.


N,N'-Methylenebismorpholine is also used in the synthesis of pharmaceuticals and agrochemicals, and as a solvent for the extraction of natural products.
N,N'-Methylenebismorpholine is widely used as a low toxicity broad spectrum fungicide for water-based metalworking fluid.
In addition, N,N’-Methylenebismorpholine is used in the preparation of catalysts, in the synthesis of polymers, and in the preparation of functionalized materials.


N,N’-Methylenebismorpholine is widely used as a low toxicity broad spectrum fungicide for water-based metalworking fluid.
N,N'-Methylenebismorpholine is also used in the synthesis of a variety of organic compounds, including pharmaceuticals and agrochemicals.
With the benefits of low skin irritation, mild odor, low toxicity; formulation compatibility, lasting bactericidal, this biocide N,N'-Methylenebismorpholine is well-known in the MWFs additives.


N,N’-Methylenebismorpholine is also used in the synthesis of pharmaceuticals and agrochemicals, and as a solvent for the extraction of natural products.
N,N’-Methylenebismorpholine is employed as intermediate for pharmaceutical.
N,N'-Methylenebismorpholine is an important industrial solvent and is used in a variety of industries, including pharmaceuticals, chemicals, plastics, and adhesives.


N,N’-Methylenebismorpholine is also used in the synthesis of a variety of organic compounds, including pharmaceuticals and agrochemicals.
With the benefits of low skin irritation, mild odor, low toxicity; formulation compatibility, lasting bactericidal, this biocide N,N’-Methylenebismorpholine is well-known in the MWFs additives.


N,N'-Methylenebismorpholine is employed as intermediate for pharmaceutical.
N,N'-Methylenebismorpholine is employed as intermediate for pharmaceutical.
N,N’-Methylenebismorpholine should be used at an addition level of 2 – 6% in a concentrate and at 0.3% in finished cutting fluid user dilutions, in order to have a concentration of 1,000 to 1,500 ppm of the active.


N,N’-Methylenebismorpholine is an important industrial solvent and is used in a variety of industries, including pharmaceuticals, chemicals, plastics, and adhesives.
In addition, N,N'-Methylenebismorpholine is used in the preparation of catalysts, in the synthesis of polymers, and in the preparation of functionalized materials.
N,N’-Methylenebismorpholine is successfully applied for the preservation, mineral oil containing, water-miscible coolants.



SCIENTIFIC RESEARCH APPLICATION OF N,N'-METHYLENEBISMORPHOLINE:
N,N'-Methylenebismorpholine has a wide range of applications in scientific research, including as a solvent for organic synthesis, as a reagent for the synthesis of organic compounds, and as a medium for chromatography.



ADVANTAGES AND LIMITATIONS FOR LAB EXPERIMENTS OF N,N'-METHYLENEBISMORPHOLINE:
N,N'-Methylenebismorpholine has several advantages for laboratory experiments.
N,N'-Methylenebismorpholine is a relatively inexpensive solvent, and is widely available.
N,N'-Methylenebismorpholine is also a relatively non-toxic solvent, and can be used in a variety of reactions.



FEATURE OF N,N'-METHYLENEBISMORPHOLINE:
1. Anti-bacteria and fungl effectively.
2. MBM fully meet with the requirements of water-based metalworking fluid;
3. N,N'-Methylenebismorpholine has low skin irritation, mild odor, low toxicity;
4. Formulation compatibility, lasting bactericidal.
At higher concentrations, fungi and molds also have better inhibition.



BENEFITS OF N,N'-METHYLENEBISMORPHOLINE:
1, a low toxicity broad spectrum fungicide for water-based metalworking fluid
2, anti-Bacteria and fungi effectively
3, fully meet with the requirements of water-based metalworking fluid: low skin irritation, mild odor, low toxicity; formulation compatibility, lasting bactericidal.
At higher concentrations, fungi and molds also have better inhibition.
Recommended addition amount (mass ratio): Recipe 2-3%, the working liquid 1-2‰;



FUTURE DIRECTIONS OF N,N'-METHYLENEBISMORPHOLINE:
There are a number of potential future directions for the use of N,N'-Methylenebismorpholine.
One potential direction is the development of new methods for the synthesis of organic compounds, as dimorphoN,N'-Methylenebismorpholine linomethane can facilitate the reaction of different molecules by allowing them to interact with each other more easily.
Another potential direction is the development of new catalysts and functionalized materials, as N,N'-Methylenebismorpholine can act as a proton acceptor and facilitate the formation of hydrogen bonds between molecules.
Finally, further research into the use of N,N'-Methylenebismorpholine as a solvent for the extraction of natural products could help to identify potential applications in the pharmaceutical and agrochemical industries.



SYNTHESIS METHOD OF N,N'-METHYLENEBISMORPHOLINE:
N,N'-Methylenebismorpholine is synthesized through a variety of methods, including the reaction of dimethyl sulfate with ammonium hydroxide, the reaction of formaldehyde with dimethyl sulfate, and the reaction of dimethyl sulfoxide with formaldehyde.
N,N'-Methylenebismorpholine can also be synthesized through the reaction of dimethyl sulfoxide with ammonia, and through the reaction of dimethyl sulfoxide with formic acid.



BIOCHEMICAL AND PHYSIOLOGICAL EFFECTS OF N,N'-METHYLENEBISMORPHOLINE:
N,N'-Methylenebismorpholine is a volatile, colorless liquid with a characteristic odor.



MECHANISM OF ACTION OF N,N'-METHYLENEBISMORPHOLINE:
N,N'-Methylenebismorpholine is a polar aprotic solvent, meaning that it has a low dielectric constant and a low boiling point.
This makes it an ideal solvent for many organic reactions, as N,N'-Methylenebismorpholine has a low solubility for most organic compounds.
As a result, N,N'-Methylenebismorpholine can facilitate the reaction of different molecules by allowing them to interact with each other more easily.
In addition, N,N'-Methylenebismorpholine can act as a proton acceptor, allowing the formation of hydrogen bonds between molecules.



PHYSICAL and CHEMICAL PROPERTIES of N,N'-METHYLENEBISMORPHOLINE:
Appearance: Colorless liquid
Density: 1.05-1.10g/cm3
PH (1% water): 9.0-11.5
Solubility in Water: completely
Molecular Formula: C9H18N2O2
Molar Mass: 186.25
Density: 1,04 g/cm3
Boling Point: 122-124°C 12mm
Flash Point: 77.6°C
Water Solubility: Soluble in water.
Vapor Presure: 0.00935mmHg at 25°C
pKa: 6.91±0.10(Predicted)
Storage Condition: 2-8°C
Refractive Index: 1.4790 (estimate)

Molecular Weight: 186.25
XLogP3-AA: -0.3
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 186.136827821
Monoisotopic Mass: 186.136827821
Topological Polar Surface Area: 24.9 Ų
Heavy Atom Count: 13
Formal Charge: 0
Complexity: 127
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Molecular Formula: C9H18N2O2
Molar Mass: 186.25
Density: 1,04 g/cm3
Boling Point: 122-124°C 12mm
Flash Point: 77.6°C
Water Solubility: Soluble in water.
Vapor Presure: 0.00935mmHg at 25°C
pKa: 6.91±0.10(Predicted)
Storage Condition: 2-8°C
Refractive Index: 1.4790 (estimate)
Density: 1.1±0.1 g/cm3
Boiling Point: 265.1±35.0 °C at 760 mmHg
Molecular Formula: C9H18N2O2
Molecular Weight: 186.251
Flash Point: 77.6±23.2 °C
Exact Mass: 186.136826
PSA: 24.94000
LogP: -0.06
Vapour Pressur: 0.0±0.5 mmHg at 25°C
Index of Refraction: 1.497

Purity of Active Content: >92%
Appearance: Colorless liquid
Density: 1.08-1.10g/cm3
Boiling point °C: 122-124(P=12torr)
PH (1% water): 9.0-11.0
Solubility in Water: completely
Physical state: liquid
Color: No data available
Odor: No data available
Melting point/freezing point:
Melting point/range: 18 - 21 °C
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 115 °C - open cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 16 mPa.s at 20 °C proportions, Hydrolysis
Partition coefficient: n-octanol/water:
log Pow: < 0,3 at 30 °C
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Boiling point: 122-124°C 12mm
Density: 1,04 g/cm3
refractive index: 1.4790 (estimate)
storage temp.: 2-8°C
pka: 6.91±0.10(Predicted)
Water Solubility: Soluble in water.



FIRST AID MEASURES of N,N'-METHYLENEBISMORPHOLINE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Do not attempt to neutralise.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of N,N'-METHYLENEBISMORPHOLINE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up carefully with liquid-absorbent material.
Dispose of properly.



FIRE FIGHTING MEASURES of N,N'-METHYLENEBISMORPHOLINE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of N,N'-METHYLENEBISMORPHOLINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of N,N'-METHYLENEBISMORPHOLINE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of N,N'-METHYLENEBISMORPHOLINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available



SYNONYMS:
4,4'-Methylenene (MORPHOLINE)
4,4'-Methylenebismorpholine
Bis (Morpholino) Methane
Methylenebismorpholine
Morpholine, 4,4'-Methylenebis-
Morpholine, 4,4'-amthylenedi-
n, n'-methalenebismorpholine
N,N'-Dimorpholinomethane
4,4'-methylenedimorpholine
DIMORPHOLINOMETHONE
DIMORPHOLINOMETHANE
N,N-Dimorpholinomethane
5625-90-1
Dimorpholinomethane
N,N'-Dimorpholinomethane
4,4'-Methylenedimorpholine
4,4-Methylenedimorpholine
4-(morpholin-4-ylmethyl)morpholine
N,N'-Methylenebismorpholine
Morpholine, 4,4'-methylenebis-
bis(4-morpholinyl)methane
n,n'-methylene-bis-morpholine
MORPHOLINE, 4,4'-METHYLENEDI-
MFCD00023369
4,4'-Methylenebismorpholine
7O79DZW79Z
4-[(morpholin-4-yl)methyl]morpholine
Bismorpholino methane
Dimorpholinomethone
Bis(morpholino-)methan
EINECS 227-062-3
BRN 0111886
UNII-7O79DZW79Z
AI3-62944
bismorpholinomethane
Contram ST-1
methylenebismorpholine
bis(morpholino)methane
N,N\'-Dimorpholinomethane
4,4-methylene-bismorpholine
Oprea1_332757
4,4'-methanediyldimorpholine
N,N'-Methylene bismorpholine
4-27-00-00203 (Beilstein Handbook Reference)
SCHEMBL536772
DTXSID8052859
Bis(4-morpholinyl)methane, 98%
ZINC19324145
AKOS002314380
4,4'-METHYLENEBIS(MORPHOLINE)
FS-4049
MORPHOLINE44METHYLENEDI
BIS-(MORPHOLINE-)METHANE
44METHYLENEBISMORPHOLINE
Bis(4-morpholinyl)methane
N,N'-Methylenebismorpholine
4,4-methylenebis-Morpholine
N,N'-Methylenebismorpholine
Morpholine,4,4-Methylenebis-
4,4'-methanediyldimorpholine
Morpholine,4,4-methylenebis-
N,N'-Methylene-bis-morpholine
Methylene-bis-morpholine,N,N'-
AC-12628
SY032818
DB-052882
CS-0236719
FT-0629594
EN300-172423
Q865946
W-110051
F2163-0188
N,N'-DIMORPHOLINOMETHANE
4,4'-methylenedi-morpholin
4,4'-methylenedimorpholine
bis(morpholino-)methan
bismorpholinomethane
N,N'-Methylenebismorpholine
DIMORPHOLINOMETHANE
DIMORPHOLINOMETHONE
N,N'-DIMORPHOLINOMETHANE
N,N-Dimorpholinomethane
Morpholine,4,4-methylenebis-
Bis(4-morpholinyl)methane
N,N'-Methylenebismorpholine
4,4'-methanediyldimorpholine
-bis-morpholine
4,4′-Methylenebis[morpholine]
4,4′-Methylenedimorpholine
4,4'-Dimorpholinylmethane
4,4'-Methylenebismorpholine
44METHYLENEBISMORPHOLINE
BIS-(MORPHOLINE-)METHANE
Bis(morpholino)methane
DIMORPHOLINOMETHANE
DIMORPHOLINOMETHONE
Methylenebismorpholine
Methylene-bis-morpholine,N,N'-
Morpholine, 4,4′-methylenebis-
Morpholine, 4,4′-methylenedi-
Morpholine,4,4-Methylenebis-
MORPHOLINE44METHYLENEDI
N,N′-Methylenebismorpholine;
N,N′-methylenebismorpholine
formaldehyde released from N,N′-methylenebismorpholine
N,N′-methylenebismorpholine
formaldehyde released by N,N′-methylenebismorpholine / MBM
DIMORPHOLINOMETHANE
4,4’-methylenedi-morpholin
4,4’-methylenedimorpholine
bis(morpholino-)methan
bismorpholinomethane
N,N’-Methylenebismorpholine
DIMORPHOLINOMETHANE
N,N'-DIMORPHOLINOMETHANE
4,4’-methylenedi-morpholin
4,4’-methylenedimorpholine
bis(morpholino-)methan
bismorpholinomethane
N,N’-Methylenebismorpholine
DIMORPHOLINOMETHONE
Morpholine,4,4-Methylenebis-
Methylene-bis-morpholine,N,N'-
MORPHOLINE44METHYLENEDI
44METHYLENEBISMORPHOLINE
BIS-(MORPHOLINE-)METHANE
DIMORPHOLINOMETHONE
DIMORPHOLINOMETHANE
N,N-Dimorpholinomethane
MORPHOLINE44METHYLENEDI
BIS-(MORPHOLINE-)METHANE
44METHYLENEBISMORPHOLINE
Bis(4-morpholinyl)methane
N,N'-Methylenebismorpholine
4,4-methylenebis-Morpholine
N,N'-Methylenebismorpholine
Morpholine,4,4-Methylenebis-
4,4'-methanediyldimorpholine
Morpholine,4,4-methylenebis-
N,N'-Methylene-bis-morpholine
Methylene-bis-morpholine,N,N'-
DIMORPHOLINOMETHONE
N,N'-Dimorpholinomethane
N,N´-Methylene bismorpholine
Bis (morpholino-) methan
Bismorpholino methane
4,4-Methylenedimorpholine
Morpholine, 4,4-methylenedi-
DIMORPHOLINOMETHONE
DIMORPHOLINOMETHANE
N,N-Dimorpholinomethane
MORPHOLINE44METHYLENEDI
BIS-(MORPHOLINE-)METHANE
44METHYLENEBISMORPHOLINE
Bis(4-morpholinyl)methane
N,N'-Methylenebismorpholine
4,4-methylenebis-Morpholine
N,N'-Methylenebismorpholine
Morpholine,4,4-Methylenebis-
4,4'-methanediyldimorpholine
Morpholine,4,4-methylenebis-
N,N'-Methylene-bis-morpholine
Methylene-bis-morpholine,N,N'-
N,N-Dimorpholinomethane
Morpholine,4,4-methylenebis-
Bis(4-morpholinyl)methane
N,N'-Methylenebismorpholine
4,4'-methanediyldimorpholine
4,4-methylenebis-Morpholine
N,N-Methylene-bis-morpholine



N,N'-METHYLENEBISMORPHOLINE
N,N'-Methylenebismorpholine, also known as dimethylformamide (DMF), is an organic compound belonging to the class of amides, and is one of the most widely used solvents in the world.
N,N'-Methylenebismorpholine is a colorless, volatile liquid with a characteristic odor and a relatively low boiling point.


CAS Number: 5625-90-1
EC Number: 227-062-3
MDL Number: MFCD00023369
Molecular Formula: C9H18N2O2


N,N'-Methylenebismorpholine is soluble in water.
N,N’-Methylenebismorpholine is a highly concentrated industrial bactericide based on tetrahydrooxazines.
Owing to its good solubility N,N’-Methylenebismorpholine is suitable for oily as well as aqueous systems.


N,N’-Methylenebismorpholine is soluble in water.
N,N’-Methylenebismorpholine is effective against gram-negative and gram positive bacterias.
N,N’-Methylenebismorpholine, also known as dimethylformamide (DMF), is an organic compound belonging to the class of amides, and is one of the most widely used solvents in the world.



USES and APPLICATIONS of N,N'-METHYLENEBISMORPHOLINE:
N,N'-Methylenebismorpholine is widely used as a low toxicity broad spectrum fungicide for water-based metalworking fluid.
With the benefits of low skin irritation, mild odor, low toxicity; formulation compatibility, lasting bactericidal, this biocide N,N'-Methylenebismorpholine is well-known in the MWFs additives.
N,N'-Methylenebismorpholine is employed as intermediate for pharmaceutical.


N,N'-Methylenebismorpholine is an important industrial solvent and is used in a variety of industries, including pharmaceuticals, chemicals, plastics, and adhesives.
N,N'-Methylenebismorpholine is also used in the synthesis of a variety of organic compounds, including pharmaceuticals and agrochemicals.
N,N'-Methylenebismorpholine is also used in the synthesis of pharmaceuticals and agrochemicals, and as a solvent for the extraction of natural products.


In addition, N,N'-Methylenebismorpholine is used in the preparation of catalysts, in the synthesis of polymers, and in the preparation of functionalized materials.
N,N'-Methylenebismorpholine is employed as intermediate for pharmaceutical.
N,N’-Methylenebismorpholine is successfully applied for the preservation, mineral oil containing, water-miscible coolants.


Compared to hexahydrotriazines and oxazolidines, N,N’-Methylenebismorpholine is more stable in metalworking concentrates.
N,N’-Methylenebismorpholine should be used at an addition level of 2 – 6% in a concentrate and at 0.3% in finished cutting fluid user dilutions, in order to have a concentration of 1,000 to 1,500 ppm of the active.
N,N’-Methylenebismorpholine is widely used as a low toxicity broad spectrum fungicide for water-based metalworking fluid.


With the benefits of low skin irritation, mild odor, low toxicity; formulation compatibility, lasting bactericidal, this biocide N,N’-Methylenebismorpholine is well-known in the MWFs additives.
N,N’-Methylenebismorpholine is employed as intermediate for pharmaceutical.
N,N’-Methylenebismorpholine is an important industrial solvent and is used in a variety of industries, including pharmaceuticals, chemicals, plastics, and adhesives.


N,N’-Methylenebismorpholine is also used in the synthesis of a variety of organic compounds, including pharmaceuticals and agrochemicals.
N,N’-Methylenebismorpholine is also used in the synthesis of pharmaceuticals and agrochemicals, and as a solvent for the extraction of natural products.


In addition, N,N’-Methylenebismorpholine is used in the preparation of catalysts, in the synthesis of polymers, and in the preparation of functionalized materials.
N,N’-Methylenebismorpholine is employed as intermediate for pharmaceutical.



BENEFITS OF N,N'-METHYLENEBISMORPHOLINE:
1, a low toxicity broad spectrum fungicide for water-based metalworking fluid
2, anti-Bacteria and fungi effectively
3, fully meet with the requirements of water-based metalworking fluid: low skin irritation, mild odor, low toxicity; formulation compatibility, lasting bactericidal.
At higher concentrations, fungi and molds also have better inhibition.
Recommended addition amount (mass ratio): Recipe 2-3%, the working liquid 1-2‰;



SYNTHESIS METHOD OF N,N'-METHYLENEBISMORPHOLINE:
N,N'-Methylenebismorpholine is synthesized through a variety of methods, including the reaction of dimethyl sulfate with ammonium hydroxide, the reaction of formaldehyde with dimethyl sulfate, and the reaction of dimethyl sulfoxide with formaldehyde.
N,N'-Methylenebismorpholine can also be synthesized through the reaction of dimethyl sulfoxide with ammonia, and through the reaction of dimethyl sulfoxide with formic acid.



SCIENTIFIC RESEARCH APPLICATION OF N,N'-METHYLENEBISMORPHOLINE:
N,N'-Methylenebismorpholine has a wide range of applications in scientific research, including as a solvent for organic synthesis, as a reagent for the synthesis of organic compounds, and as a medium for chromatography.



MECHANISM OF ACTION OF N,N'-METHYLENEBISMORPHOLINE:
N,N'-Methylenebismorpholine is a polar aprotic solvent, meaning that it has a low dielectric constant and a low boiling point.
This makes it an ideal solvent for many organic reactions, as N,N'-Methylenebismorpholine has a low solubility for most organic compounds.
As a result, N,N'-Methylenebismorpholine can facilitate the reaction of different molecules by allowing them to interact with each other more easily.
In addition, N,N'-Methylenebismorpholine can act as a proton acceptor, allowing the formation of hydrogen bonds between molecules.



BIOCHEMICAL AND PHYSIOLOGICAL EFFECTS OF N,N'-METHYLENEBISMORPHOLINE:
N,N'-Methylenebismorpholine is a volatile, colorless liquid with a characteristic odor.



ADVANTAGES AND LIMITATIONS FOR LAB EXPERIMENTS OF N,N'-METHYLENEBISMORPHOLINE:
N,N'-Methylenebismorpholine has several advantages for laboratory experiments.
N,N'-Methylenebismorpholine is a relatively inexpensive solvent, and is widely available.
N,N'-Methylenebismorpholine is also a relatively non-toxic solvent, and can be used in a variety of reactions.



FUTURE DIRECTIONS OF N,N'-METHYLENEBISMORPHOLINE:
There are a number of potential future directions for the use of N,N'-Methylenebismorpholine.
One potential direction is the development of new methods for the synthesis of organic compounds, as dimorphoN,N'-Methylenebismorpholine linomethane can facilitate the reaction of different molecules by allowing them to interact with each other more easily.
Another potential direction is the development of new catalysts and functionalized materials, as N,N'-Methylenebismorpholine can act as a proton acceptor and facilitate the formation of hydrogen bonds between molecules.
Finally, further research into the use of N,N'-Methylenebismorpholine as a solvent for the extraction of natural products could help to identify potential applications in the pharmaceutical and agrochemical industries.



PHYSICAL and CHEMICAL PROPERTIES of N,N'-METHYLENEBISMORPHOLINE:
Molecular Weight: 186.25
XLogP3-AA: -0.3
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 186.136827821
Monoisotopic Mass: 186.136827821
Topological Polar Surface Area: 24.9 Ų
Heavy Atom Count: 13
Formal Charge: 0
Complexity: 127
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Molecular Formula: C9H18N2O2
Molar Mass: 186.25
Density: 1,04 g/cm3
Boling Point: 122-124°C 12mm
Flash Point: 77.6°C
Water Solubility: Soluble in water.
Vapor Presure: 0.00935mmHg at 25°C
pKa: 6.91±0.10(Predicted)
Storage Condition: 2-8°C
Refractive Index: 1.4790 (estimate)
Density: 1.1±0.1 g/cm3
Boiling Point: 265.1±35.0 °C at 760 mmHg
Molecular Formula: C9H18N2O2
Molecular Weight: 186.251
Flash Point: 77.6±23.2 °C
Exact Mass: 186.136826
PSA: 24.94000
LogP: -0.06
Vapour Pressur: 0.0±0.5 mmHg at 25°C
Index of Refraction: 1.497

Purity of Active Content: >92%
Appearance: Colorless liquid
Density: 1.08-1.10g/cm3
Boiling point °C: 122-124(P=12torr)
PH (1% water): 9.0-11.0
Solubility in Water: completely
Physical state: liquid
Color: No data available
Odor: No data available
Melting point/freezing point:
Melting point/range: 18 - 21 °C
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 115 °C - open cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 16 mPa.s at 20 °C proportions, Hydrolysis
Partition coefficient: n-octanol/water:
log Pow: < 0,3 at 30 °C
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Boiling point: 122-124°C 12mm
Density: 1,04 g/cm3
refractive index: 1.4790 (estimate)
storage temp.: 2-8°C
pka: 6.91±0.10(Predicted)
Water Solubility: Soluble in water.



FIRST AID MEASURES of N,N'-METHYLENEBISMORPHOLINE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Do not attempt to neutralise.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of N,N'-METHYLENEBISMORPHOLINE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up carefully with liquid-absorbent material.
Dispose of properly.



FIRE FIGHTING MEASURES of N,N'-METHYLENEBISMORPHOLINE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of N,N'-METHYLENEBISMORPHOLINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of N,N'-METHYLENEBISMORPHOLINE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of N,N'-METHYLENEBISMORPHOLINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available



SYNONYMS:
5625-90-1
Dimorpholinomethane
N,N'-Dimorpholinomethane
4,4'-Methylenedimorpholine
4,4-Methylenedimorpholine
4-(morpholin-4-ylmethyl)morpholine
N,N'-Methylenebismorpholine
Morpholine, 4,4'-methylenebis-
bis(4-morpholinyl)methane
n,n'-methylene-bis-morpholine
MORPHOLINE, 4,4'-METHYLENEDI-
MFCD00023369
4,4'-Methylenebismorpholine
7O79DZW79Z
4-[(morpholin-4-yl)methyl]morpholine
Bismorpholino methane
Dimorpholinomethone
Bis(morpholino-)methan
EINECS 227-062-3
BRN 0111886
UNII-7O79DZW79Z
AI3-62944
bismorpholinomethane
Contram ST-1
methylenebismorpholine
bis(morpholino)methane
N,N\'-Dimorpholinomethane
4,4-methylene-bismorpholine
Oprea1_332757
4,4'-methanediyldimorpholine
N,N'-Methylene bismorpholine
4-27-00-00203 (Beilstein Handbook Reference)
SCHEMBL536772
DTXSID8052859
Bis(4-morpholinyl)methane, 98%
ZINC19324145
AKOS002314380
4,4'-METHYLENEBIS(MORPHOLINE)
FS-4049
AC-12628
SY032818
DB-052882
CS-0236719
FT-0629594
EN300-172423
Q865946
W-110051
F2163-0188
N,N'-DIMORPHOLINOMETHANE
4,4'-methylenedi-morpholin
4,4'-methylenedimorpholine
bis(morpholino-)methan
bismorpholinomethane
N,N'-Methylenebismorpholine
DIMORPHOLINOMETHANE
DIMORPHOLINOMETHONE
N,N'-DIMORPHOLINOMETHANE
4,4’-methylenedi-morpholin
4,4’-methylenedimorpholine
bis(morpholino-)methan
bismorpholinomethane
N,N’-Methylenebismorpholine
DIMORPHOLINOMETHANE
DIMORPHOLINOMETHONE
N,N'-Dimorpholinomethane
N,N´-Methylene bismorpholine
Bis (morpholino-) methan
Bismorpholino methane
4,4-Methylenedimorpholine
Morpholine, 4,4-methylenedi-
DIMORPHOLINOMETHONE
DIMORPHOLINOMETHANE
N,N-Dimorpholinomethane
MORPHOLINE44METHYLENEDI
BIS-(MORPHOLINE-)METHANE
44METHYLENEBISMORPHOLINE
Bis(4-morpholinyl)methane
N,N'-Methylenebismorpholine
4,4-methylenebis-Morpholine
N,N'-Methylenebismorpholine
Morpholine,4,4-Methylenebis-
4,4'-methanediyldimorpholine
Morpholine,4,4-methylenebis-
N,N'-Methylene-bis-morpholine
Methylene-bis-morpholine,N,N'-
N,N-Dimorpholinomethane
Morpholine,4,4-methylenebis-
Bis(4-morpholinyl)methane
N,N'-Methylenebismorpholine
4,4'-methanediyldimorpholine
4,4-methylenebis-Morpholine
N,N-Methylene-bis-morpholine
N,N-Dimorpholinomethane
Morpholine,4,4-methylenebis-
Bis(4-morpholinyl)methane
N,N'-Methylenebismorpholine
4,4'-methanediyldimorpholine
-bis-morpholine
4,4′-Methylenebis[morpholine]
4,4′-Methylenedimorpholine
4,4'-Dimorpholinylmethane
4,4'-Methylenebismorpholine
44METHYLENEBISMORPHOLINE
BIS-(MORPHOLINE-)METHANE
Bis(morpholino)methane
DIMORPHOLINOMETHANE
DIMORPHOLINOMETHONE
Methylenebismorpholine
Methylene-bis-morpholine,N,N'-
Morpholine, 4,4′-methylenebis-
Morpholine, 4,4′-methylenedi-
Morpholine,4,4-Methylenebis-
MORPHOLINE44METHYLENEDI
N,N′-Methylenebismorpholine;
N,N′-methylenebismorpholine
formaldehyde released from N,N′-methylenebismorpholine
N,N′-methylenebismorpholine
formaldehyde released by N,N′-methylenebismorpholine / MBM
DIMORPHOLINOMETHANE
N,N'-DIMORPHOLINOMETHANE
4,4’-methylenedi-morpholin
4,4’-methylenedimorpholine
bis(morpholino-)methan
bismorpholinomethane
N,N’-Methylenebismorpholine
DIMORPHOLINOMETHONE
Morpholine,4,4-Methylenebis-
Methylene-bis-morpholine,N,N'-
MORPHOLINE44METHYLENEDI
44METHYLENEBISMORPHOLINE
BIS-(MORPHOLINE-)METHANE
DIMORPHOLINOMETHONE
DIMORPHOLINOMETHANE
N,N-Dimorpholinomethane
MORPHOLINE44METHYLENEDI
BIS-(MORPHOLINE-)METHANE
44METHYLENEBISMORPHOLINE
Bis(4-morpholinyl)methane
N,N'-Methylenebismorpholine
4,4-methylenebis-Morpholine
N,N'-Methylenebismorpholine
Morpholine,4,4-Methylenebis-
4,4'-methanediyldimorpholine
Morpholine,4,4-methylenebis-
N,N'-Methylene-bis-morpholine
Methylene-bis-morpholine,N,N'-


N,N'-METHYLENE-BIS-MORPHOLINE
N,N'-Methylene-bis-morpholine is soluble in water.
N,N'-Methylene-bis-morpholine is synthesized using a proprietary process that ensures high purity and consistency.


CAS Number: 5625-90-1
EC Number: 227-062-3
MDL Number: MFCD00023369
Molecular formula: C9H18N2O2


N,N'-Methylene-bis-morpholine is a low toxicity broad spectrum fungicide for water-based metalworking fluid.
N,N'-Methylene-bis-morpholine is anti-Bacteria and fungi effectively.
N,N'-Methylene-bis-morpholine is fully meet with the requirements of water-based metalworking fluid.


N,N'-Methylene-bis-morpholine is soluble in water.
One of the key benefits of N,N'-Methylene-bis-morpholine is its ability to act as a chelating agent, meaning it can bind to metal ions and prevent them from reacting with other chemicals.


This property makes N,N'-Methylene-bis-morpholine an ideal additive in the production of pharmaceuticals, where it can help to stabilize active ingredients and prevent degradation over time.
In addition, N,N'-Methylene-bis-morpholine is a versatile solvent that can dissolve a wide range of organic compounds.


This makes N,N'-Methylene-bis-morpholine useful in the production of polymers and resins, where it can help to dissolve and disperse additives and other chemicals.
N,N'-Methylene-bis-morpholine is also used in the production of adhesives, where it can help to improve the viscosity and adhesion of the final product.


In terms of market prospects, N,N'-Methylene-bis-morpholine is a promising chemical that is expected to see continued growth in the coming years.
As the demand for polymers, resins, and pharmaceuticals continues to increase, the need for solvents and stabilizers like N,N'-Methylene-bis-morpholine will also rise.


Furthermore, the use of N,N'-Methylene-bis-morpholine in the production of PVC and other plastics is expected to grow as the demand for sustainable and eco-friendly materials increases.
This is due to the fact that N,N'-Methylene-bis-morpholine is a non-toxic and biodegradable chemical that can be easily recycled or disposed of.
N,N'-Methylene-bis-morpholine is synthesized using a proprietary process that ensures high purity and consistency.



USES and APPLICATIONS of N,N'-METHYLENE-BIS-MORPHOLINE:
N,N'-Methylene-bis-morpholine is mainly used in the production of rubber vulcanization accelerators, and also used in the synthesis of surfactants, textile printing and dyeing auxiliaries, medicines and pesticides.
N,N'-Methylene-bis-morpholine is also used as a catalyst for the polymerization of cis-butadiene, a corrosion inhibitor, and an optical bleach.


N,N'-Methylene-bis-morpholine is employed as intermediate for pharmaceutical.
N,N'-Methylene-bis-morpholine is also a solvent for dyes, resins, waxes, early gums, casein, and so on.
The salts of morpholine are also widely used.


Morpholine hydrochloride is an intermediate of organic synthesis. Morpholine fatty acid salt can be used as a coating agent for the skin of fruits or melons and vegetables, and can appropriately inhibit the respiration of the base and preventthe evaporation of water and the shrinkage of epidermis.
N,N'-Methylene-bis-morpholine is suitable for emulsions, semi-synthetic and synthetic metalworking fluids.


In conclusion, N,N'-Methylene-bis-morpholine is a highly versatile and useful chemical that offers a wide range of benefits for various industries.
Its ability to act as a chelating agent, solvent, and stabilizer make N,N'-Methylene-bis-morpholine an ideal additive in the production of polymers, resins, and pharmaceuticals.


N,N'-Methylene-bis-morpholine is employed as intermediate for pharmaceutical.
N,N'-Methylene-bis-morpholine is used primarily as a solvent in the production of polymers, resins, and pharmaceuticals.
N,N'-Methylene-bis-morpholine is also used as a stabilizer in the production of PVC and other plastics.



FEATURES OF N,N'-METHYLENE-BIS-MORPHOLINE:
● Broad-spectrum biocide, can effectively inhibit and kill bacteria, fungi and yeasts.
● N,N'-Methylene-bis-morpholine has good compatibility with additives such as surfactants in the formula, and has no adverse effect on the stability of the metalworking fluids.
● N,N'-Methylene-bis-morpholine helps to improve the PH value of the metalworking fluids.
● N, N'-Methylene-bis-morpholine has better inhibitory effect on mold and fungus at higher concentration.
● N,N'-Methylene-bis-morpholine can be used alone or in combination with other biocides.



PHYSICAL and CHEMICAL PROPERTIES of N,N'-METHYLENE-BIS-MORPHOLINE:
CAS: 5625-90-1
EINECS: 227-062-3
InChI: InChI=1/C9H18N2O2/c1-5-12-6-2-10(1)9-11-3-7-13-8-4-11/h1-9H2
InChIKey: MIFZZKZNMWTHJK-UHFFFAOYSA-N
Molecular Formula: C9H18N2O2
Molar Mass: 186.25
Density: 1,04 g/cm3
Boling Point: 122-124°C 12mm
Flash Point: 77.6°C
Water Solubility: Soluble in water.
Vapor Presure: 0.00935mmHg at 25°C
pKa: 6.91±0.10(Predicted)
Storage Condition: 2-8°C
Refractive Index: 1.4790 (estimate)
Molecular weight: 186.25
EINECS: 227-062-3
SMILES: N1(CN2CCOCC2)CCOCC1
InChI: MIFZZKZNMWTHJK-UHFFFAOYSA-N
InChIKey: 1S/C9H18N2O2/c1-5-12-6-2-10(1)9-11-3-7-13-8-4-11/h1-9H2
Water solubility: Soluble in water.
Density: 1,04 g/cm3
Boiling Point: 122-124°C 12mm
Notes: N,N'-Methylene bismorpholine uses and applications include: Biocide

Class: Specialty Chemicals
Physical state: liquid
Color: No data available
Odor: No data available
Melting point/freezing point:
Melting point/range: 18 - 21 °C
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 115 °C - open cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 16 mPa.s at 20 °C
Water solubility at 10 - 30 °C - miscible in all proportions, Hydrolysis
Partition coefficient: n-octanol/water:
log Pow: < 0,3 at 30 °C
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available

Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Appearance: Transparent liquid
Assay: 92%min
Color: 2max
Refractive index: 70-80
PH(1% aq.solution): 9.5-11.5
Formula : C9H18N2O2
Molecular Weight : 186
CAS NO. : 5625-90-1
Assay (G.C.) : ≥92%
Density : 1.08-1.1
Boiling point : 265.1ºC
Flash point : 80ºC
Boiling point: 122-124°C 12mm
Density: 1,04 g/cm3
refractive index: 1.4790 (estimate)
storage temp.: 2-8°C
pka: 6.91±0.10(Predicted)
Water Solubility: Soluble in water.
InChIKey: MIFZZKZNMWTHJK-UHFFFAOYSA-N

CAS DataBase Reference: 5625-90-1(CAS DataBase Reference)
FDA UNII: 7O79DZW79Z
EPA Substance Registry System: Morpholine, 4,4'-methylenebis- (5625-90-1)
Molecular Weight: 186.251
Exact Mass: 186.25
EC Number: 227-062-3
UNII: 7O79DZW79Z
DSSTox ID: DTXSID8052859
PSA: 24.94000
XLogP3: -0.06
Density: 1.0494 g/cm3 @ Temp: 20 °C
Boiling Point: 139-140 °C
Flash Point: 77.6±23.2 °C
Refractive Index: 1.497
Water Solubility: Soluble in water.
Molecular Weight: 186.25 g/mol
XLogP3-AA: -0.3
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 186.136827821 g/mol
Monoisotopic Mass: 186.136827821 g/mol
Topological Polar Surface Area: 24.9Ų

Heavy Atom Count: 13
Formal Charge: 0
Complexity: 127
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Molecular weight: 186.25
EINECS: 227-062-3
SMILES: N1(CN2CCOCC2)CCOCC1
InChI: MIFZ ZKZNMWTHJK-UHFFFAOYSA-N
InChIKey: 1S/C9H18N2O2/c1-5-12-6-2-10(1)9-11-3-7-13-8-4-11/h1-9H2
Water solubility: Soluble in water.
Density: 1,04 g/cm3
Boiling Point: 122-124°C 12mm
CAS: 5625-90-1
EINECS: 227-062-3
InChI: InChI=1/C9H18N2O2/c1-5-12-6-2-10(1)9-11-3-7-13-8-4-11/h1-9H2
InChIKey: MIFZZKZNMWTHJK-UHFFFAOYSA-N
Molecular Formula: C9H18N2O2
Molar Mass: 186.25
Density: 1,04 g/cm3
Boling Point: 122-124°C 12mm
Flash Point: 77.6°C
Water Solubility: Soluble in water.
Vapor Presure: 0.00935mmHg at 25°C
pKa: 6.91±0.10(Predicted)
Storage Condition: 2-8°C
Refractive Index: 1.4790 (estimate)



FIRST AID MEASURES of N,N'-METHYLENE-BIS-MORPHOLINE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Do not attempt to neutralise.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of N,N'-METHYLENE-BIS-MORPHOLINE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully with liquid-absorbent material.
Dispose of properly.
Clean up affected area.


FIRE FIGHTING MEASURES of N,N'-METHYLENE-BIS-MORPHOLINE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of N,N'-METHYLENE-BIS-MORPHOLINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of N,N'-METHYLENE-BIS-MORPHOLINE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of N,N'-METHYLENE-BIS-MORPHOLINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available



SYNONYMS:
DIMORPHOLINOMETHONE
DIMORPHOLINOMETHANE
N,N-Dimorpholinomethane
MORPHOLINE44METHYLENEDI
BIS-(MORPHOLINE-)METHANE
44METHYLENEBISMORPHOLINE
Bis(4-morpholinyl)methane
N,N'-Methylenebismorpholine
4,4-methylenebis-Morpholine
N,N'-Methylenebismorpholine
Morpholine,4,4-Methylenebis-
4,4'-methanediyldimorpholine
Morpholine,4,4-methylenebis-
N,N'-Methylene-bis-morpholine
Methylene-bis-morpholine,N,N'-
N,N'-DIMORPHOLINOMETHANE
4,4'-methylenedi-morpholin
4,4'-methylenedimorpholine
bis(morpholino-)methan
bismorpholinomethane
N,N'-Methylenebismorpholine
DIMORPHOLINOMETHANE
DIMORPHOLINOMETHONE
N,N'-DIMORPHOLINOMETHANE
4,4’-methylenedi-morpholin
4,4’-methylenedimorpholine
bis(morpholino-)methan
bismorpholinomethane
N,N’-Methylenebismorpholine
DIMORPHOLINOMETHANE
DIMORPHOLINOMETHONE
N,N'-Dimorpholinomethane
N,N´-Methylene bismorpholine
Bis (morpholino-) methan
Bismorpholino methane
4,4-Methylenedimorpholine
Morpholine, 4,4-methylenedi-
Morpholine, 4,4'-methylenebis-
N,N'methylenebismorpholine
[formaldehyde released from N,N'-methylenebismorpholine]
[MBM]
Bis-acrylamide
N,N-Methylene-bis-acrylamide
N,N'-Methylenebis(2-propenamide)
MBA; NAPP
Bis-acrylamide
N,N-Methylene-bis-acrylamide
N,N'-Methylenebis(2-propenamide)
MBA; NAPP
4-(Morpholin-4-ylMethyl)Morpholine
Conncide MW
DIMORPHOLINOMETHONE
DIMORPHOLINOMETHANE
bismorpholinomethane
bis(morpholino-)methan
MORPHOLINE44METHYLENEDI
BIS-(MORPHOLINE-)METHANE
44METHYLENEBISMORPHOLINE
N,N'-DIMORPHOLINOMETHANE
Morpholine,4,4′-methylenebis-
Morpholine,4,4′-methylenedi-
4,4′-Methylenebis[morpholine]
Dimorpholinomethane
Bis(morpholino)methane
4,4′-Methylenedimorpholine
Methylenebismorpholine
N,N′-Methylenebismorpholine
5625-90-1
Dimorpholinomethane
N,N'-Dimorpholinomethane
4,4'-Methylenedimorpholine
4-(morpholin-4-ylmethyl)morpholine
4,4-Methylenedimorpholine
Morpholine, 4,4'-methylenebis-
N,N'-Methylenebismorpholine
bis(4-morpholinyl)methane
MORPHOLINE, 4,4'-METHYLENEDI-
MFCD00023369
4-[(morpholin-4-yl)methyl]morpholine
4,4'-Methylenebismorpholine
7O79DZW79Z
Bismorpholino methane
Dimorpholinomethone
n,n'-methylene-bis-morpholine
Bis(morpholino-)methan
EINECS 227-062-3
BRN 0111886
4,4-methylenebis-Morpholine
UNII-7O79DZW79Z
AI3-62944
bismorpholinomethane
Contram ST-1
methylenebismorpholine
bis(morpholino)methane
4,4-methylene-bismorpholine
Oprea1_332757
4,4'-methanediyldimorpholine
4-27-00-00203 (Beilstein Handbook Reference)
SCHEMBL536772
DTXSID8052859
AKOS002314380
4,4'-METHYLENEBIS(MORPHOLINE)
FS-4049
AC-12628
SY032818
CS-0236719
FT-0629594
EN300-172423
Q865946
W-110051
F2163-0188
Morpholine, 4,4'-methylenedi- (6CI,7CI,8CI)
4,4'-Methylenebis[morpholine]
Bis(morpholino)methane
Dimorpholinomethane
Methylenebismorpholine
N,N'-Methylenebismorpholine
Morpholine, 4,4′-methylenebis-
Morpholine, 4,4′-methylenedi-
4,4′-Methylenebis[morpholine]
Dimorpholinomethane
Bis(morpholino)methane
4,4′-Methylenedimorpholine
Methylenebismorpholine
N,N′-Methylenebismorpholine
DIMORPHOLINOMETHONE
DIMORPHOLINOMETHANE
N,N-Dimorpholinomethane
MORPHOLINE44METHYLENEDI
BIS-(MORPHOLINE-)METHANE
44METHYLENEBISMORPHOLINE
Bis(4-morpholinyl)methane
N,N'-Methylenebismorpholine
4,4-methylenebis-Morpholine
N,N'-Methylenebismorpholine
Morpholine,4,4-Methylenebis-
4,4'-methanediyldimorpholine
Morpholine,4,4-methylenebis-
N,N'-Methylene-bis-morpholine
Methylene-bis-morpholine,N,N'-



N.N-DIMETHYLACETAMIDE
2-(Dimethylamino)Ethanol; N,N-Dimethyl-N-ethanolamine; N,N-Dimethyl-2-aminoethanol; beta-Dimethylaminoethyl alcohol; beta-hydroxyethyldimethylamine; Ddimethylaminoethanol; Deanol; Dimethylethanolamine; Dimethylaminoaethanol (German); N,N-Dimethyl-2-Hydroxyethylamine; N,N-Dimethylaminoethanol; N,N-dimethyl-N-(2-hydroxyethyl)amine; cas no: 108-01-0
N.N-DIMETHYLETHANOLAMINE      
Tetrasodium (1-hydroxyethylidene)bisphosphonate; Tetra Sodium Salt of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid; ETIDRONIC ACID, TETRASODIUM SALT; 1-Hydroxyethane-1,1-diphosphonic acid , Tetrasodium salt; 1-Hydroxyethylidene-1,1-diphosphonic acid, Tetrasodium salt; Sodium HEDP; HEDPS; 1-hydroxyethylidenedi(phosphonic acid), Tetrasodium salt; (Hydroxyethylidene) diphosphonic acid, Tetrasodium salt; Tetra Sodium Salt of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid CAS NO:3794-83-0
Na4HEDP
Tetrasodium (1-hydroxyethylidene)bisphosphonate; Tetra Sodium Salt of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid; ETIDRONIC ACID, TETRASODIUM SALT; 1-Hydroxyethane-1,1-diphosphonic acid , Tetrasodium salt; 1-Hydroxyethylidene-1,1-diphosphonic acid, Tetrasodium salt; Sodium HEDP; HEDPS; 1-hydroxyethylidenedi(phosphonic acid), Tetrasodium salt; (Hydroxyethylidene) diphosphonic acid, Tetrasodium salt; Tetra Sodium Salt of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid CAS NO:3794-83-0
NABR (SODIUM BROMIDE)

Sodium bromide, commonly known as NaBr, is an ionic compound with the chemical formula NaBr.
NaBr (Sodium bromide) is a white crystalline powder that is highly soluble in water and has a salty taste.
NaBr (Sodium bromide) is an alkali metal halide and is composed of a sodium cation (Na+) and a bromide anion (Br−).

NaBr (Sodium bromide)
CAS Number: 7647-15-6
EC Number: 231-599-9



APPLICATIONS


NaBr (Sodium bromide) is used in the oil and gas industry as a completion and workover fluid.
NaBr (Sodium bromide) is used as a sedative for horses and other large animals.
NaBr (Sodium bromide) is used in the manufacture of photographic film and paper.

NaBr (Sodium bromide) is used as a flame retardant in some plastics.
NaBr (Sodium bromide) is used in some pharmaceuticals as a sedative and hypnotic agent.

NaBr (Sodium bromide) is used as a disinfectant in water treatment.
NaBr (Sodium bromide) is used in the production of other bromine compounds.

NaBr (Sodium bromide) is used in the preparation of certain dyes.
NaBr (Sodium bromide) is used in some veterinary medicines.
NaBr (Sodium bromide) is used in the manufacture of some specialty chemicals.

NaBr (Sodium bromide) is used in some hair and skincare products.
NaBr (Sodium bromide) is used as an electrolyte in some batteries.

NaBr (Sodium bromide) is used in the production of some agricultural chemicals.
NaBr (Sodium bromide) is used in the preparation of some perfumes and fragrances.

NaBr (Sodium bromide) is used in some dental procedures as an antiseptic and analgesic.
NaBr (Sodium bromide) is used in some food products as a preservative.
NaBr (Sodium bromide) is used in the synthesis of some organic compounds.

NaBr (Sodium bromide) is used in some swimming pools as a disinfectant and algae control agent.
NaBr (Sodium bromide) is used in the textile industry as a dyeing and printing auxiliary.

NaBr (Sodium bromide) is used in the preparation of some cosmetics.
NaBr (Sodium bromide) is used in the manufacture of some flame retardants.

NaBr (Sodium bromide) is used in some pulp and paper manufacturing processes.
NaBr (Sodium bromide) is used in the production of some biocides.

NaBr (Sodium bromide) is used in some metal finishing and plating processes.
NaBr (Sodium bromide) is used in some antifreeze and deicing products.


Sodium bromide (NaBr) has various applications in different fields, including:

Photography:

NaBr (Sodium bromide) is used as a source of bromide ions in silver bromide emulsion, which is used in photographic film and paper.


Oil drilling:

NaBr (Sodium bromide) is used as a completion and workover fluid in oil and gas drilling operations.
NaBr (Sodium bromide) is used to prevent the swelling of shale and clay formations and improve the stability of the wellbore.


Chemical synthesis:

NaBr (Sodium bromide) is used as a reagent in various chemical reactions, such as the preparation of organobromine compounds.


Water treatment:

NaBr (Sodium bromide) is used as a disinfectant in water treatment plants to control the growth of microorganisms.


Pharmaceutical industry:

NaBr (Sodium bromide) is used as an anticonvulsant in the treatment of epilepsy.


Animal health:

NaBr (Sodium bromide) is used in veterinary medicine as a sedative, anticonvulsant, and antiseptic.


Food industry:

NaBr (Sodium bromide) is used as a preservative in some food products, such as bread.


Flame retardants:

NaBr (Sodium bromide) is used as a flame retardant in some plastics, textiles, and other materials.


Textile industry:

NaBr (Sodium bromide) is used in the dyeing of textiles as a leveling agent to ensure even dyeing.


Chemical analysis:

NaBr (Sodium bromide) is used in the laboratory for the preparation of solutions and for the analysis of various chemical compounds.


Electroplating:

NaBr (Sodium bromide) is used in electroplating baths to deposit metallic coatings on substrates.


Heat transfer fluids:

NaBr (Sodium bromide) is used in heat transfer fluids to prevent corrosion and scale formation.


Metal processing:

NaBr (Sodium bromide) is used in metal processing to remove impurities from the surface of metals.


Glass industry:

NaBr (Sodium bromide) is used as a fluxing agent in the production of glass to lower the melting point of the materials.


Wood preservatives:

NaBr (Sodium bromide) is used as a wood preservative to protect the wood from decay and insect infestation.


Corrosion inhibitors:

NaBr (Sodium bromide) is used as a corrosion inhibitor in various industries to protect metals from corrosion.


Soil stabilization:

NaBr (Sodium bromide) is used in soil stabilization to improve the stability of soil and prevent erosion.


Bleaching agents:

NaBr (Sodium bromide) is used as a bleaching agent in the pulp and paper industry.


Swimming pool disinfection:

NaBr (Sodium bromide) is used in swimming pool disinfection to control the growth of algae and bacteria.


Polymer production:

NaBr (Sodium bromide) is used in the production of some polymers as a chain transfer agent.


Herbicides:

NaBr (Sodium bromide) is used in the formulation of some herbicides to control the growth of weeds.


Textile finishing:

NaBr (Sodium bromide) is used in textile finishing to improve the hand of the fabric.


Tanning industry:

NaBr (Sodium bromide) is used in the tanning industry as a deliming agent to remove lime from the hides.


Gas scrubbing:

NaBr (Sodium bromide) is used in gas scrubbing operations to remove impurities from the gas stream.


Fumigants:

NaBr (Sodium bromide) is used as a fumigant to control pests in some agricultural products.


NaBr (Sodium bromide) is used as a sedative in veterinary medicine.
NaBr (Sodium bromide) is used in the preparation of photographic emulsions.

NaBr (Sodium bromide) is used in the manufacturing of drilling fluids for oil and gas wells.
NaBr (Sodium bromide) is used as a reagent in the chemical industry.
NaBr (Sodium bromide) is used in the textile industry for dyeing and printing fabrics.

NaBr (Sodium bromide) is used as a flame retardant in plastics and textiles.
NaBr (Sodium bromide) is used in the production of brominated compounds, such as bromoalkanes and bromoesters.

NaBr (Sodium bromide) is used in the preparation of pharmaceuticals, such as sedatives and anticonvulsants.
NaBr (Sodium bromide) is used in the production of photographic chemicals, such as silver bromide.
NaBr (Sodium bromide) is used as a preservative in the food industry.

NaBr (Sodium bromide) is used in the production of bromine for disinfectants and pesticides.
NaBr (Sodium bromide) is used as a source of bromine for organic synthesis.

NaBr (Sodium bromide) is used in water treatment as a disinfectant and oxidizing agent.
NaBr (Sodium bromide) is used in the production of flame retardant materials for aircraft and other transportation vehicles.

NaBr (Sodium bromide) is used in the manufacture of synthetic fibers and polymers.
NaBr (Sodium bromide) is used as a laboratory reagent for various chemical reactions.

NaBr (Sodium bromide) is used in the production of pigments and dyes.
NaBr (Sodium bromide) is used in the production of ceramics and glass.
NaBr (Sodium bromide) is used as an electrolyte in some batteries.

NaBr (Sodium bromide) is used in the production of brominated flame retardants for electrical and electronic equipment.
NaBr (Sodium bromide) is used in the manufacture of photographic film and paper.

NaBr (Sodium bromide) is used in the production of silver bromide for photographic applications.
NaBr (Sodium bromide) is used in the production of surfactants and detergents.

NaBr (Sodium bromide) is used in the production of fire extinguishers.
NaBr (Sodium bromide) is used in the production of veterinary medicines and supplements for livestock.



DESCRIPTION


Sodium bromide, commonly known as NaBr, is an ionic compound with the chemical formula NaBr.
NaBr (Sodium bromide) is a white crystalline powder that is highly soluble in water and has a salty taste.
NaBr (Sodium bromide) is an alkali metal halide and is composed of a sodium cation (Na+) and a bromide anion (Br−).

NaBr (Sodium bromide) is a white crystalline powder.
NaBr (Sodium bromide) is an ionic compound with the chemical formula NaBr.
NaBr (Sodium bromide) has a high melting point of 747°C and a boiling point of 1,390°C.

NaBr (Sodium bromide) is soluble in water, but insoluble in most organic solvents.
NaBr (Sodium bromide) is hygroscopic, which means it readily absorbs moisture from the air.

NaBr (Sodium bromide) has a salty taste and is used as a food preservative.
NaBr (Sodium bromide) is an inorganic compound commonly used in the manufacture of photography, medicines, and drilling fluids.

NaBr (Sodium bromide) is a strong oxidizing agent and can react violently with reducing agents.
NaBr (Sodium bromide) is a halide salt and can form toxic fumes of bromine gas upon contact with acids, acid fumes, and oxidizing agents.
NaBr (Sodium bromide) is commonly used as a source of bromide ions in organic synthesis and as a reagent in analytical chemistry.

NaBr (Sodium bromide) is also used in the production of flame retardants, dyes, and disinfectants.
NaBr (Sodium bromide) can be used as a sedative in medicine and as a component of mineral supplements.

NaBr (Sodium bromide) can be used as a catalyst in some chemical reactions.
NaBr (Sodium bromide) is used in the oil and gas industry as a completion fluid to increase the density of drilling fluids.

NaBr (Sodium bromide) has a refractive index of 1.641, making it useful in the production of optical lenses and glass.
NaBr (Sodium bromide) can be used as a disinfectant for swimming pools and spas.
NaBr (Sodium bromide) is a non-combustible solid, but can enhance combustion of other substances.

NaBr (Sodium bromide) has a molar mass of 102.89 g/mol and a density of 3.203 g/cm³.
NaBr (Sodium bromide) can be toxic if ingested in large quantities and can cause skin and eye irritation upon contact.

NaBr (Sodium bromide) is stable under normal conditions, but can decompose at high temperatures or when exposed to strong oxidizing agents.
NaBr (Sodium bromide) has a wide range of applications in the food, pharmaceutical, and chemical industries.

NaBr (Sodium bromide) can be used as a coagulant in wastewater treatment and as a flux in metallurgy.
NaBr (Sodium bromide) is commonly used as a bromide source in the preparation of organobromine compounds.

NaBr (Sodium bromide) can react with chlorine to form sodium hypobromite, a disinfectant used in water treatment.
NaBr (Sodium bromide) is a common laboratory reagent and is readily available in most chemical supply stores.



PROPERTIES


Chemical formula: NaBr
Molar mass: 102.894 g/mol
Appearance: white crystalline powder
Odor: odorless
Density: 3.203 g/cm3
Melting point: 747 °C (1,377 °F; 1,020 K)
Boiling point: 1,390 °C (2,530 °F; 1,660 K)
Solubility in water: 90.5 g/100 mL (25 °C); 121 g/100 mL (50 °C)
Solubility in ethanol: 1.1 g/100 mL (20 °C)
Solubility in acetone: 0.37 g/100 mL (20 °C)
Solubility in methanol: 0.82 g/100 mL (20 °C)
Solubility in ammonia: 47.8 g/100 mL (20 °C)
Solubility in pyridine: 19.4 g/100 mL (20 °C)
Crystal structure: face-centered cubic (fcc)
Refractive index (nD): 1.641
Dielectric constant: 5.8
Thermal conductivity: 0.321 W/(cm·K)
Specific heat capacity: 0.825 J/(g·K)
Viscosity: 2.82 cP (25 °C)
pH of a 0.1 M aqueous solution: 7.5
Hazard identification number: UN 1564
NFPA 704 (fire diamond) rating: 0 1 0



FIRST AID


The first aid measures for sodium bromide (NaBr) depend on the type and severity of exposure.
Here are some general guidelines:

If NaBr (Sodium bromide) comes into contact with your skin or eyes, flush the affected area with plenty of water for at least 15 minutes.

If you inhale NaBr (Sodium bromide) dust or mist, move to an area with fresh air immediately and seek medical attention if you experience any breathing difficulties.

If you swallow NaBr (Sodium bromide), do not induce vomiting.
Rinse your mouth with water and drink plenty of water or milk to dilute the chemical.
Seek medical attention immediately.

If NaBr (Sodium bromide) comes into contact with clothing or other materials, remove the contaminated items and wash the affected skin thoroughly.


In case of any exposure to NaBr (Sodium bromide), it is important to seek medical attention promptly.



HANDLING AND STORAGE


Handling:

Wear appropriate personal protective equipment (PPE), such as gloves and eye/face protection, when handling NaBr.
Avoid contact with skin, eyes, and clothing.

Use in a well-ventilated area to avoid inhalation of dust or fumes.
Do not eat, drink or smoke when handling NaBr.
Do not mix with incompatible substances.


Storage:

Store NaBr in a cool, dry, well-ventilated area away from heat, sparks, and flame.
Keep container tightly closed when not in use.

Store away from incompatible materials.
Do not store near acids or acidic materials.

Store in a secure, upright position to prevent containers from falling or being knocked over.
Do not store in direct sunlight or in areas with high temperatures or humidity.



SYNONYMS


Sodium bromide anhydrous
Bromide salt of sodium
UNII-0JG1KSW2VL
Natriumbromid (German)
Bromure de sodium (French)
Sodio bromuro (Italian)
Bromuro de sodio (Spanish)
Halite
Sedoneural
Sedonevril
Sodium bromatum (Latin)
Sodium bromidum (Latin)
Sodiumbromide
Bromnatrium
UN1459
HSDB 940
EINECS 231-599-9
BRN 3587175
AI3-50287
DTXSID5023476
CTK1D9626
MolPort-003-926-011
ACT05680
CHEBI:63093
Bromide of sodium
Natrium bromatum
Sedoneural
Sodium bromatum
Bromnatrium
Sedoneural forte
Sodium bromide (NaBr)
Unii-767ip0y0sy
Bromide sodium
Sodium bromide, anhydrous
Bromide, sodium
Hydrobromic acid sodium salt
Natrium bromidum
Sedoneural N
Sodium bromide, puriss p.a., ACS reagent, ≥99.0%
UNII-767IP0Y0SY
7647-15-6
AI3-01964
Bromide of soda
LS-142227
Sodium bromide (anhydrous)
Sodium monobromide
Bromnatrii
DTXSID1022389
Natrii bromidum.
NA-CMC (SODIUM CARBOXYMETHYL CELLULOSE)
Na-CMC (Sodium carboxymethyl cellulose) is a white or slightly yellowish, almost odourless and tasteless hydroscopic powder, consisting of very fine particles, fine granules or fine fibres.
Na-CMC (Sodium carboxymethyl cellulose) is a water soluble polymer which can be used as a polyelectrolyte cellulose derivative.
Na-CMC (Sodium carboxymethyl cellulose) belongs to the class of anionic linear structured cellulose.

CAS Number: 9004-32-4
Molecular Formula: C6H7O2(OH)2CH2COONa
EINECS Number: 618-378-6

Na-CMC (Sodium carboxymethyl cellulose) is biodegradable, but not readily biodegradable, and it is not expected to bioaccumulate.
Na-CMC (Sodium carboxymethyl cellulose) is components consist of polysaccharide composed of fibrous tissues of plants.
Na-CMC (Sodium carboxymethyl cellulose) is a water dispersible sodium salt of carboxy-methyl ether of cellulose that forms a clear colloidal solution.

Na-CMC (Sodium carboxymethyl cellulose) is a hygroscopic material that has the ability to absorb more than 50% of water at high humidity.
Na-CMC (Sodium carboxymethyl cellulose) is also a natural polymeric derivative that can be used in detergents, food and textile industries.
Na-CMC (Sodium carboxymethyl cellulose) is a water-soluble polymer.

As a solution in water, Na-CMC (Sodium carboxymethyl cellulose) has thixotropic properties.
Na-CMC (Sodium carboxymethyl cellulose) is useful in helping to hold the components of pyrotechnic compositions in aqucous suspension (e.g., in the making of black match).
Na-CMC (Sodium carboxymethyl cellulose) is also an especially effective binder that can be used in small amounts in compositions, where the binder can intcrfere with the intended effect (e.g., in strobe compositions).

However, its sodium content obviously precludes its use in most color compositions.
Na-CMC (Sodium carboxymethyl cellulose) is manufactured from cellulose by various proccsses that replacc some of the hy drogen atoms in the hydroxyl[OH] groups of the cellulose molecule with acidic carboxymethyl [-CH2CO.OH] groups,which are neutralized to form the corresponding sodium salt.
Na-CMC (Sodium carboxymethyl cellulose) is white when pure; industrial grade material may be grayish-white or cream granules or powder.

Na-CMC (Sodium carboxymethyl cellulose) is a low concern for toxicity to aquatic organisms.
Na-CMC (Sodium carboxymethyl cellulose) is used for its thickening and swelling properties in a wide range of complex formulated products for pharmaceutical, food, home, and personal care applications, as well as in paper, water treatment, and mineral processing industries.
Na-CMC (Sodium carboxymethyl cellulose) is tackifier, at room temperature, it is non-toxic tasteless white flocculent powder, it is stable and soluble in water, aqueous solution is neutral or alkaline transparent viscous liquid, it is soluble in other water-soluble gums and resins, it is insoluble in organic solvents such as ethanol.

Na-CMC (Sodium carboxymethyl cellulose) is the substituted product of cellulosic carboxymethyl group.
According to their molecular weight or degree of substitution, Na-CMC (Sodium carboxymethyl cellulose) can be completely dissolved or insoluble polymer, the latter can be used as the weak acid cation of exchanger to separate neutral or basic proteins.
Na-CMC (Sodium carboxymethyl cellulose) can form highly viscous colloidal solution with adhesive, thickening, flowing, emulsifying, shaping, water, protective colloid, film forming, acid, salt, suspensions and other characteristics, and it is physiologically harmless, so it is widely used in the food, pharmaceutical, cosmetic, oil, paper, textiles, construction and other areas of production.

Na-CMC (Sodium carboxymethyl cellulose) is a white or slightly yellowish powder.
Na-CMC (Sodium carboxymethyl cellulose) or cellulose gum is a cellulose derivative with carboxymethyl groups (-CH2-COOH) bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone.
Na-CMC (Sodium carboxymethyl cellulose) is often used as its sodium salt, sodium carboxymethyl cellulose.

Na-CMC (Sodium carboxymethyl cellulose) used to be marketed under the name Tylose, a registered trademark of SE Tylose.
A semisynthetic, water-soluble polymer in which CH 2 COOH groups are substituted on the glucose units of the cellulose chain through an ether link- age.
Since the reaction occurs in an alkaline medium, the prod- uct is the sodium salt of the carboxylic acid R-O- CH 2 COONa.

Na-CMC (Sodium carboxymethyl cellulose) for oenological use is prepared exclusively from wood by treatment with alkali and monochloroacetic acid or its sodium salt.
Na-CMC (Sodium carboxymethyl cellulose) inhibits tartaric precipitation through a "protective colloid" effect.
Na-CMC (Sodium carboxymethyl cellulose) a colorless, odorless, water-soluble polymer.

Sodium carboxymethyl cellulose, NaCMC or CMC, was first developed in 1947.
Commonly known as carboxymethyl cellulose, it is composed of the sodium salt of an alkaline modified cellulose.
Na-CMC (Sodium carboxymethyl cellulose) is water-soluble but will react with heavy metal salts to form films that are clear, tough and insoluble in water.

Na-CMC (Sodium carboxymethyl cellulose) is thixotropic, becoming less viscous when agitated.
In most cases, Na-CMC (Sodium carboxymethyl cellulose) functions as a polyelectrolyte.
Na-CMC (Sodium carboxymethyl cellulose) is used commercially in detergents, food product and as size for textiles and paper.

In conservation, Na-CMC (Sodium carboxymethyl cellulose) has been used as an adhesive for textiles and paper.
Aging studies indicate that most Na-CMC (Sodium carboxymethyl cellulose) polymers have very good stability with negligible discoloration or weight loss.
Na-CMC (Sodium carboxymethyl cellulose) is the sodium salt of carboxymethyl cellulose, an anionic derivative.

Na-CMC (Sodium carboxymethyl cellulose) is widely used in oral and topical pharmaceutical formulations, primarily for its viscosity-increasing properties.
Viscous aqueous solutions are used to suspend powders intended for either topical application or oral and parenteral administration.
Na-CMC (Sodium carboxymethyl cellulose) may also be used as a tablet binder and disintegrant, and to stabilize emulsions.

Higher concentrations, usually 3–6%, of the medium-viscosity grade are used to produce gels that can be used as the base for applications and pastes; glycols are often included in such gels to prevent them drying out.
Na-CMC (Sodium carboxymethyl cellulose) is also used in self-adhesive ostomy, wound care, and dermatological patches as a muco-adhesive and to absorb wound exudate or transepidermal water and sweat.

This muco-adhesive property is used in products designed to prevent post-surgical tissue adhesions; and to localize and modify the release kinetics of active ingredients applied to mucous membranes; and for bone repair.
Encapsulation with carboxymethylcellulose sodium can affect drug protection and delivery.
There have also been reports of its use as a cyto-protective agent.

Na-CMC (Sodium carboxymethyl cellulose) is also used in cosmetics, toiletries, surgical prosthetics, and incontinence, personal hygiene, and food products.
Na-CMC (Sodium carboxymethyl cellulose) is one of the most significant byproducts of cellulose ethers which are created by natural cellulose modification as a type of cellulose derivate with an ether structure.
Termed Na-CMC (Sodium carboxymethyl cellulose), this polymer has a poor water solubility of the acid form of CMC and is typically preserved as sodium carboxymethylcellulose.

Na-CMC (Sodium carboxymethyl cellulose) is utilized in numerous industries and is referred to as monosodium glutamate in the workplace.
Na-CMC (Sodium carboxymethyl cellulose) is an offshoot of CMC.
Na-CMC (Sodium carboxymethyl cellulose) is a crucial by-product of cellulose ethers and is typically created by altering natural cellulose.

Since the Na-CMC (Sodium carboxymethyl cellulose) compound is typically poorly soluble in water, sodium CMC can be used to preserve it.
Na-CMC (Sodium carboxymethyl cellulose) has dispersibility and is soluble in cold water.
Emulsifying dispersion and solid dispersion are two of sodium Na-CMC (Sodium carboxymethyl cellulose)'s peculiar chemical properties.

Na-CMC (Sodium carboxymethyl cellulose) can be categorized as a derivative of a natural polymer.
Na-CMC (Sodium carboxymethyl cellulose), one of major cellulosic ethers, is widely used as a binding, thickening and stabilising agent (Lee et al. 2018).
Pharmaceutical grades of Na-CMC (Sodium carboxymethyl cellulose) are available commercially at degree of substitution (DS) values of 0.7, 0.9, and 1.2, with a corresponding sodium content of 6.5%–12% wt.

Na-CMC (Sodium carboxymethyl cellulose) is also available in several different viscosity grades.
Na-CMC (Sodium carboxymethyl cellulose) is highly soluble in water at all temperatures, forming clear solutions.
Na-CMC (Sodium carboxymethyl cellulose)s solubility depends on its degree of substitution.

Na-CMC (Sodium carboxymethyl cellulose) is an anionic water-soluble polymer based on renewable cellulosic raw material.
Na-CMC (Sodium carboxymethyl cellulose) functions as a rheology modifier, binder, dispersant, and an excellent film former.
These attributes make Na-CMC (Sodium carboxymethyl cellulose) a preferred choice as a bio-based hydrocolloid in multiple applications.

Na-CMC (Sodium carboxymethyl cellulose) acts as a thickener, binder, stabilizer, suspending agent and flow controlling agent.
Na-CMC (Sodium carboxymethyl cellulose) forms fine films that are resistant to oils, greases, and organic solvents.
Na-CMC (Sodium carboxymethyl cellulose) dissolves rapidly in cold water. 4) Acts as a protective colloid reducing water losses.

Na-CMC (Sodium carboxymethyl cellulose) is suitable for use in food systems.
Na-CMC (Sodium carboxymethyl cellulose) is physiologically inert.
Na-CMC (Sodium carboxymethyl cellulose) is an anionic polyelectrolyte.

Na-CMC (Sodium carboxymethyl cellulose) is a family of chemically modified cellulose derivatives containing the carboxymethyl ether group (-O-CH2-COO-) bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone.
When Carboxymethylcellulose is recovered and presented as the Sodium salt, the resulting polymer is what is known as Na-CMC (Sodium carboxymethyl cellulose), and has the general chemical formula, [C6H7O2(OH)x(OCH2COONa)y]n.

Na-CMC (Sodium carboxymethyl cellulose) was discovered shortly after Word War 1 and has been produced commercially since the early 1930s.
Na-CMC (Sodium carboxymethyl cellulose) is produced by treating cellulose with an aqueous sodium hydroxide solution followed by monochloroacetic acid or its sodium salt.
In a parallel reaction two by-products, sodium chloride and sodium glycolate, are produced.

Once these by-products are removed, high purity Sodium carboxymethylcellulose is obtained.
As a general rule, the obtained material has a slight excess of sodium hydroxide and has to be neutralised.
The neutralisation endpoint can affect the properties of the material.

In the final step, the material is dried, milled to the desired particle size, and packaged.
Na-CMC (Sodium carboxymethyl cellulose), often abbreviated as Na-CMC or simply CMC, is a versatile and widely used chemical compound.

Na-CMC (Sodium carboxymethyl cellulose) is derived from cellulose, a natural polymer found in the cell walls of plants.
Na-CMC (Sodium carboxymethyl cellulose) is a water-soluble polymer and is used for a variety of purposes in various industries, including food, pharmaceuticals, cosmetics, and more.

Melting point: 274 °C (dec.)
Density: 1,6 g/cm3
FEMA: 2239 | CARBOXYMETHYLCELLULOSE
storage temp.: room temp
solubility: H2O: 20 mg/mL, soluble
form: low viscosity
pka: 4.30(at 25℃)
color: White to light yellow
Odor: Odorless
PH Range: 6.5 - 8.5
PH: pH (10g/l, 25℃) 6.0~8.0
Viscosity: 900 to 1400 mPa-s(1 %, H2O, 25 ℃)
Water Solubility: soluble
Merck: 14,1829

Alkali cellulose is prepared by steeping cellulose obtained from wood pulp or cotton fibers in sodium hydroxide solution.
The alkaline cellulose is then reacted with sodium monochloroacetate to produce Na-CMC (Sodium carboxymethyl cellulose).
Sodium chloride and sodium glycolate are obtained as by-products of this etherification.

Na-CMC (Sodium carboxymethyl cellulose) is used warm water or cold water when preparing the solution, and stir till it completely melts.
The amout of added water depends on variety and the use of multiple requirements.
High viscosity Na-CMC (Sodium carboxymethyl cellulose) is a white or slightly yellow fibrous powder, hygroscopic, odorless, tasteless, non-toxic, easy to ferment, insoluble in acids, alcohols and organic solvents, easily dispersed to form colloidal solution in water.

Na-CMC (Sodium carboxymethyl cellulose) is reacted by the acid and fibrous cotton, it is mainly used for water-based drilling fluids tackifier, it has certain role of fluid loss, it has strong salt and temperature resistance especially.
Na-CMC (Sodium carboxymethyl cellulose) is incompatible with strongly acidic solutions and with the soluble salts of iron and some other metals, such as aluminum, mercury, and zinc.

Na-CMC (Sodium carboxymethyl cellulose) is also incompatible with xanthan gum.
Precipitation may occur at pH < 2, and also when it is mixed with ethanol (95%).
Na-CMC (Sodium carboxymethyl cellulose) forms complex coacervates with gelatin and pectin.

Na-CMC (Sodium carboxymethyl cellulose) also forms a complex with collagen and is capable of precipitating certain positively charged proteins.
Food and pharmaceutical grade Carboxymethylcellulose is required by law to contain not less than 99.5% pure Na-CMC (Sodium carboxymethyl cellulose) and a maximum of 0.5% of residual salts (sodium chloride and sodium glycolate).

The degree of substitution (DS) can vary between 0.2-1.5, although it is generally in the range of 0.6-0.95.
The DS determines the behaviour of Na-CMC (Sodium carboxymethyl cellulose) in water: Grades with DS >0.6 form colloidal solutions in water that are transparent and clear, i.e the higher the content of carboxymethyl groups, the higher the solubility and smoother the solutions obtained.
Na-CMC (Sodium carboxymethyl cellulose) with a DS below 0.6 tends to be only partially soluble.

Na-CMC (Sodium carboxymethyl cellulose) is available as a white to almost white, odourless, tasteless, granular powder.
Na-CMC (Sodium carboxymethyl cellulose) is an anionic polymer with a clarified solution dissolved in cold or hot water.
Na-CMC (Sodium carboxymethyl cellulose) functions as a thickening rheology modifier, moisture retention agent, texture/body building agent, suspension agent, and binding agent in personal products and toothpaste.

Na-CMC (Sodium carboxymethyl cellulose) is desirable because the catalysis product (glucose) is easily measured using a reducing sugar assay, such as 3,5-dinitrosalicylic acid.
Using Na-CMC (Sodium carboxymethyl cellulose) in enzyme assays is especially important in screening for cellulase enzymes that are needed for more efficient cellulosic ethanol conversion.
Na-CMC (Sodium carboxymethyl cellulose) was misused in early work with cellulase enzymes, as many had associated whole cellulase activity with CMC hydrolysis.

Na-CMC (Sodium carboxymethyl cellulose) is one of the most important products of cellulose ethers, which are formed by natural cellulose modification as a kind of cellulose derivate with an ether structure.
Due to the fact that the acid form of Na-CMC (Sodium carboxymethyl cellulose) has poor water solubility, it is usually preserved as sodium carboxymethylcellulose, which is widely used in many industries and regarded as monosodium glutamate in industry.

Na-CMC (Sodium carboxymethyl cellulose) is used in cigarette adhesive, fabric sizing, footwear paste meal, home slimy.
Na-CMC (Sodium carboxymethyl cellulose) is used in interior painting architectural, building lines melamine, thickening mortar, concrete enhancement.
Na-CMC (Sodium carboxymethyl cellulose) is synthesized by the alkali-catalyzed reaction of cellulose with chloroacetic acid.

The polar (organic acid) carboxyl groups render the cellulose soluble and chemically reactive.
Fabrics made of cellulose—e.g. cotton or viscose rayon—may also be converted into Na-CMC (Sodium carboxymethyl cellulose).
Following the initial reaction, the resultant mixture produces approximately 60% Na-CMC (Sodium carboxymethyl cellulose) and 40% salts (sodium chloride and sodium glycolate); this product is the so-called technical CMC, which is used in detergents.

An additional purification process is used to remove salts to produce pure Na-CMC (Sodium carboxymethyl cellulose), which is used for alimentary and pharmaceutical applications.
An intermediate "semi-purified" grade is also produced, typically used in paper applications such as the restoration of archival documents.
Na-CMC (Sodium carboxymethyl cellulose) is a kind of cellulose widely used and used in the world today.

Na-CMC (Sodium carboxymethyl cellulose), is a cellulose derivative with 100-2000 degree of polymerization of glucose, and its relative molecular weight is 242.16.
White fibrous or granular powder.
Na-CMC (Sodium carboxymethyl cellulose) is odourless, tasteless, tasteless, hygroscopic and insoluble in organic solvents.

Na-CMC (Sodium carboxymethyl cellulose) is used as a thickener in the food industry, as a drug carrier in the pharmaceutical industry, as a binder and anti-retrogradation agent in the daily chemical industry.
Na-CMC (Sodium carboxymethyl cellulose) is a water-soluble polymer derived from cellulose through a chemical modification process.

Carboxymethyl groups (-CH2-COOH) are introduced into the cellulose structure.
These carboxymethyl groups make the cellulose molecule more water-soluble and provide it with its unique properties.
The viscosity of Na-CMC (Sodium carboxymethyl cellulose) solutions can be controlled by adjusting the concentration of the polymer.

This property makes it suitable for a wide range of applications, from thin solutions in beverages to thick gels in some pharmaceutical formulations.
Na-CMC (Sodium carboxymethyl cellulose) is stable over a wide pH range, making it suitable for use in both acidic and alkaline environments.
This is particularly important in the food industry where it can be used in a variety of products with different pH levels.

Na-CMC (Sodium carboxymethyl cellulose) is generally considered safe for consumption and topical use.
Na-CMC (Sodium carboxymethyl cellulose) is non-toxic and non-allergenic, which contributes to its widespread use in food and pharmaceutical products.
Na-CMC (Sodium carboxymethyl cellulose) is highly hydrophilic, meaning it has a strong affinity for water.

This property is useful in many applications where moisture retention or water binding is required.
Na-CMC (Sodium carboxymethyl cellulose) disperses easily in cold water, forming a smooth, uniform solution, which is advantageous in manufacturing processes.
Na-CMC (Sodium carboxymethyl cellulose) can be used to form films or coatings.

Na-CMC (Sodium carboxymethyl cellulose) can be used to create edible films for various purposes, such as encapsulating flavors or improving food packaging.
Na-CMC (Sodium carboxymethyl cellulose) is cost-effective and environmentally friendly because it is derived from renewable resources, such as wood pulp or cotton cellulose.
Na-CMC (Sodium carboxymethyl cellulose) is used as a highly effective additive to improve the product and processing properties in various fields of application - from foodstuffs, cosmetics and pharmaceuticals to products for the paper and textile industries.

History:
Na-CMC (Sodium carboxymethyl cellulose) was first obtained in 1918 by the German and is granted a patent in 1921.
Na-CMC (Sodium carboxymethyl cellulose) to achieve commercial production since 1921 in Europe.
But Na-CMC (Sodium carboxymethyl cellulose) was only for the crude product which was used as colloid and binder.

From 1936 to 1941, the industrial applied research of Na-CMC (Sodium carboxymethyl cellulose) is very active, people invented several enlightening patents.
German use Na-CMC (Sodium carboxymethyl cellulose) for synthetic detergent during World War II.

In 1943, Na-CMC (Sodium carboxymethyl cellulose) was first made by Hercules Company in the United States and produced the refined product’s sodium in 1946 which are recognized as safe food ingredients.
Now, Na-CMC (Sodium carboxymethyl cellulose) is the most widely used and the largest amount of fiber in the worlds.

Synthesis:
Na-CMC (Sodium carboxymethyl cellulose) is formed when cellulose reacts with mono chloroacetic acid or its sodium salt under alkaline condition with presence of organic solvent, hydroxyl groups substituted by Sodium carboxymethyl groups in C2, C3 and C6 of glucose, which substitution slightly prevails at C2 position.
Generally, there are two steps in manufacturing process of Na-CMC (Sodium carboxymethyl cellulose), alkalinization and etherification.

Step 1: Alkalinization
Disperse the raw material cellulose pulp in alkali solution (generally sodium hydroxide, 5–50%) to obtain alkali cellulose.
Cell-OH+NaOH →Cell·O-Na+ +H2O

Step 2: Etherification
Etherification of alkali cellulose with sodium monochloroacetate (up to 30%) in an alcohol-water medium.
The mixture of alkali cellulose and reagent is heated (50–75°C) and stirred during the process.
ClCH2COOH+NaOH→ClCH2COONa+H2O

Cell·O-Na+ +ClCH2COO- →Cell-OCH2COO-Na
The DS of the sodium CMC can be controlled by the reaction conditions and use of organic solvents (such as isopropanol).

Uses:
Na-CMC (Sodium carboxymethyl cellulose) is frequently called simply carboxymethyl cellulose and also known as cellulose gum.
Na-CMC (Sodium carboxymethyl cellulose) is derived from purified cellulose from cotton and wood pulp.
Na-CMC (Sodium carboxymethyl cellulose) is a water dispersible sodium salt of carboxy-methyl ether of cellulose that forms a clear colloidal solution.

Na-CMC (Sodium carboxymethyl cellulose) is a hygroscopic material that has the ability to absorb more than 50% of water at high humidity.
Na-CMC (Sodium carboxymethyl cellulose) is also a natural polymeric derivative that can be used in detergents, food and textile industries.
Na-CMC (Sodium carboxymethyl cellulose) can be used as a binder in the preparation of graphene nano-platelet based inks for the fabrication of dye sensitized solar cells (DSSCs).

Na-CMC (Sodium carboxymethyl cellulose) can also be used as a viscosity enhancer in the development of tyrosinase based inks for the formation of electrodes for biosensor applications.
Na-CMC (Sodium carboxymethyl cellulose) is used as a support material for a variety of cathodes and anodes for microbial fuel cells.
Na-CMC (Sodium carboxymethyl cellulose) is used in refractory fiber, ceramic production molding bond.

Na-CMC (Sodium carboxymethyl cellulose) is used in oil drilling, exploration address slurry thickening, reducing water loss, quality paper surface sizing.
Na-CMC (Sodium carboxymethyl cellulose) can be used as soap and washing powder detergent active additives, as well as other industrial production on the dispersion, emulsification, stability, suspension, film, paper, polishing and the like.
Quality product can be used for toothpaste, medicine, food and other industrial sectors.

Na-CMC (Sodium carboxymethyl cellulose) is resistant to bacterial decomposition and provides a product with uniform viscosity.
Na-CMC (Sodium carboxymethyl cellulose) can prevent skin moisture loss by forming a film on the skin’s surface, and also help mask odor in a cosmetic product.
Constituents are any of several fibrous substances consisting of the chief part of a plant’s cell walls (often extracted from wood pulp or cotton).

Na-CMC (Sodium carboxymethyl cellulose) salt is used in drilling muds, in detergents as a soil-suspending agent, in resin emulsion paints, adhesives, printing inks, textile sizes and protective colloid.
Na-CMC (Sodium carboxymethyl cellulose) acts as a stabilizer in foods.
Na-CMC (Sodium carboxymethyl cellulose) is also employed in pharmaceuticals as a suspending agent and excipients for tablets.

Na-CMC (Sodium carboxymethyl cellulose) is used as viscosity modifiers to stabilize the emulsions.
Na-CMC (Sodium carboxymethyl cellulose) is used as a lubricant in artificial tears and it is used to characterize enzyme activity from endoglucanases.
Na-CMC (Sodium carboxymethyl cellulose) is used in a variety of applications ranging from food production to medical treatments.

Na-CMC (Sodium carboxymethyl cellulose) is commonly used as a viscosity modifier or thickener, and to stabilize emulsions in various products, both food and non-food.
Na-CMC (Sodium carboxymethyl cellulose) is used primarily because it has high viscosity, is nontoxic, and is generally considered to be hypoallergenic, as the major source fiber is either softwood pulp or cotton linter.
Non-food products include products such as toothpaste, laxatives, diet pills, water-based paints, detergents, textile sizing, reusable heat packs, various paper products, filtration materials, synthetic membranes, wound healing applications, and also in leather crafting to help burnish edges.

Na-CMC (Sodium carboxymethyl cellulose) is used in food under the E number E466 or E469 (when it is enzymatically hydrolyzed), as a viscosity modifier or thickener, and to stabilize emulsions in various products, including ice cream.
Na-CMC (Sodium carboxymethyl cellulose) is also used extensively in gluten-free and reduced-fat food products.
Na-CMC (Sodium carboxymethyl cellulose) is used to achieve tartrate or cold stability in wine, an innovation that may save megawatts of electricity used to chill wine in warm climates.

Na-CMC (Sodium carboxymethyl cellulose) is more stable than metatartaric acid and is very effective in inhibiting tartrate precipitation.
Na-CMC (Sodium carboxymethyl cellulose) is reported that KHT crystals, in presence of CMC, grow slower and change their morphology.
Their shape becomes flatter because they lose 2 of the 7 faces, changing their dimensions.

Na-CMC (Sodium carboxymethyl cellulose) molecules, negatively charged at wine pH, interact with the electropositive surface of the crystals, where potassium ions are accumulated.
The slower growth of the crystals and the modification of their shape are caused by the competition between Na-CMC (Sodium carboxymethyl cellulose) molecules and bitartrate ions for binding to the KHT crystals.
Na-CMC (Sodium carboxymethyl cellulose) powder is widely used in the ice cream industry, to make ice creams without churning or extremely low temperatures, thereby eliminating the need for conventional churners or salt ice mixes.

Na-CMC (Sodium carboxymethyl cellulose) is used in baking breads and cakes.
The use of Na-CMC (Sodium carboxymethyl cellulose) gives the loaf an improved quality at a reduced cost, by reducing the need of fat.
Na-CMC (Sodium carboxymethyl cellulose) is also used as an emulsifier in biscuits.

By dispersing fat uniformly in the dough, it improves the release of the dough from the moulds and cutters, achieving well-shaped biscuits without any distorted edges.
Na-CMC (Sodium carboxymethyl cellulose) can also help to reduce the amount of egg yolk or fat used in making the biscuits.
Use of Na-CMC (Sodium carboxymethyl cellulose) in candy preparation ensures smooth dispersion in flavor oils, and improves texture and quality.

Na-CMC (Sodium carboxymethyl cellulose) is used in chewing gums, margarines and peanut butter as an emulsifier.
Na-CMC (Sodium carboxymethyl cellulose) has been used extensively to characterize enzyme activity from endoglucanases (part of the cellulase complex); it is a highly specific substrate for endo-acting cellulases, as its structure has been engineered to decrystallize cellulose and create amorphous sites that are ideal for endoglucanase action.

Na-CMC (Sodium carboxymethyl cellulose) is used as a soil suspension polymer designed to deposit onto cotton and other cellulosic fabrics, creating a negatively charged barrier to soils in the wash solution.
Na-CMC (Sodium carboxymethyl cellulose) is also used as a thickening agent, for example, in the oil-drilling industry as an ingredient of drilling mud, where it acts as a viscosity modifier and water retention agent.

Na-CMC (Sodium carboxymethyl cellulose) is sometimes used as an electrode binder in advanced battery applications (i.e. lithium ion batteries), especially with graphite anodes.
Na-CMC (Sodium carboxymethyl cellulose)'s water solubility allows for less toxic and costly processing than with non-water-soluble binders, like the traditional polyvinylidene fluoride (PVDF), which requires toxic n-methylpyrrolidone (NMP) for processing.
Na-CMC (Sodium carboxymethyl cellulose) is often used in conjunction with styrene-butadiene rubber (SBR) for electrodes requiring extra flexibility, e.g. for use with silicon-containing anodes.

Na-CMC (Sodium carboxymethyl cellulose) is also used in ice packs to form a eutectic mixture resulting in a lower freezing point, and therefore more cooling capacity than ice.
Aqueous solutions of Na-CMC (Sodium carboxymethyl cellulose) have also been used to disperse carbon nanotubes, where the long Na-CMC (Sodium carboxymethyl cellulose) molecules are thought to wrap around the nanotubes, allowing them to be dispersed in water.
In conservation-restoration, Na-CMC (Sodium carboxymethyl cellulose) is used as an adhesive or fixative (commercial name Walocel, Klucel).

Apart from the question of what is Na-CMC (Sodium carboxymethyl cellulose), their uses are also very important to know.
Na-CMC (Sodium carboxymethyl cellulose) can be used as a flocculant, chelator, emulsifier, thickener, water-retentive, sizing, and film-forming substance, among other things.
Electronics, pesticides, leather, plastics, printing, ceramics, and the daily-use chemical industry are just a few of the industries that heavily utilize Na-CMC (Sodium carboxymethyl cellulose).

Additionally, Na-CMC (Sodium carboxymethyl cellulose) has a wide range of applications due to its excellent properties, widespread use, and emerging potential fields.
Na-CMC (Sodium carboxymethyl cellulose) used as sizing agent and printing paste in printing and dyeing industry.
Na-CMC (Sodium carboxymethyl cellulose) can be used as a component of oil recovery fracturing fluid in the petrochemical industry.

Na-CMC (Sodium carboxymethyl cellulose) is a widely used ionic cellulose ether, widely used in petroleum, food, medicine, construction and ceramics industries, so it is also known as "industrial monosodium glutamate".
Na-CMC (Sodium carboxymethyl cellulose) is frequently used as a thickening agent in a wide range of food products, such as salad dressings, sauces, and ice cream.
Na-CMC (Sodium carboxymethyl cellulose) imparts viscosity and helps to stabilize these products.

Na-CMC (Sodium carboxymethyl cellulose) acts as a stabilizer and prevents ingredients from separating in products like beverages, including soft drinks and fruit juices.
In salad dressings, Na-CMC (Sodium carboxymethyl cellulose) helps create stable emulsions of oil and water, preventing them from separating.
In the pharmaceutical industry, Na-CMC (Sodium carboxymethyl cellulose) can be used as a binder in tablet formulations to hold the ingredients together.

In oral suspensions and liquid medications, Na-CMC (Sodium carboxymethyl cellulose) helps to suspend solid particles uniformly in the liquid, ensuring consistent dosing.
In cosmetics and personal care products, Na-CMC (Sodium carboxymethyl cellulose) can be used to improve the moisture retention properties of creams and lotions.
Na-CMC (Sodium carboxymethyl cellulose) is used in paper manufacturing to coat the surface of paper, improving its printability and smoothness.

In the oil and gas industry, Na-CMC (Sodium carboxymethyl cellulose) can be used in drilling fluids to control viscosity and fluid loss.
Na-CMC (Sodium carboxymethyl cellulose) is sometimes used in the textile industry as a sizing agent to improve the weaving process.
For its thickening and swelling properties, Na-CMC (Sodium carboxymethyl cellulose) is used in a variety of intricately formulated products for the pharmaceutical, food, home, and personal care industries as well as the paper, water treatment, and mineral processing industries.

Thorough knowledge of the concentration-dependent rheology and relaxation response is required to design Na-CMC (Sodium carboxymethyl cellulose) solutions for applications.
Alkali cellulose and sodium chloroacetate react to form a gummy substance that is either soluble in water or swells in water.
Na-CMC (Sodium carboxymethyl cellulose) is primarily used as a thickening, emulsifying, and stabilizing agent (as in sizes for textiles and paper and pharmaceutical ointments) as well as a bulk laxative and antacid in medicine.

Safety Profile:
Na-CMC (Sodium carboxymethyl cellulose) is used in oral, topical, and some parenteral formulations.
Na-CMC (Sodium carboxymethyl cellulose) is also widely used in cosmetics, toiletries, and food products, and is generally regarded as a nontoxic and nonirritant material.
However, oral consumption of large amounts of Na-CMC (Sodium carboxymethyl cellulose) can have a laxative effect; therapeutically, 4–10 g in daily divided doses of the medium- and high-viscosity grades of carboxymethylcellulose sodium have been used as bulk laxatives.

The WHO has not specified an acceptable daily intake for Na-CMC (Sodium carboxymethyl cellulose) as a food additive since the levels necessary to achieve a desired effect were not considered to be a hazard to health.
However, in animal studies, subcutaneous administration of Na-CMC (Sodium carboxymethyl cellulose) has been found to cause inflammation, and in some cases of repeated injection fibrosarcomas have been found at the site of injection.
Hypersensitivity and anaphylactic reactions have occurred in cattle and horses, which have been attributed to Na-CMC (Sodium carboxymethyl cellulose)m in parenteral formulations such as vaccines and penicillins.

Storage:
Na-CMC (Sodium carboxymethyl cellulose) is a stable, though hygroscopic material. Under high-humidity conditions, carboxymethylcellulose sodium can absorb a large quantity (>50%) of water.
In tablets, this has been associated with a decrease in tablet hardness and an increase in disintegration time.
Aqueous solutions are stable at pH 2–10; precipitation can occur below pH 2, and solution viscosity decreases rapidly above pH 10.

Generally, solutions exhibit maximum viscosity and stability at pH 7–9.
Na-CMC (Sodium carboxymethyl cellulose) may be sterilized in the dry state by maintaining it at a temperature of 1608℃ for 1 hour.
However, this process results in a significant decrease in viscosity and some deterioration in the properties of solutions prepared from the sterilized material.

Synonyms:
SODIUM CARBOXYMETHYL CELLULOSE
9004-32-4
sodium;2,3,4,5,6-pentahydroxyhexanal;acetate
Carboxymethylcellulose sodium (USP)
Carboxymethylcellulose cellulose carboxymethyl ether
CMC powder
Celluvisc (TN)
Carmellose sodium (JP17)
CHEMBL242021
C.M.C. (TN)
CHEBI:31357
E466
Sodium carboxymethyl cellulose (MW 250000)
D01544
NANSA HS 80/NPF
Nansa HS 80/NPF is a series of organic compounds with the formula C12H25C6H4SO3Na.
Nansa HS 80/NPF is a colorless salt with beneficial properties as a surfactant.
Nansa HS 80/NPF is usually produced as a mixture of related sulfonates.

CAS Number: 11067-82-6
Molecular Formula: C18H21NaO3S
Molecular Weight: 340.41231
EINECS Number: 2342891

Nansa HS 80/NPF is a highly active anionic surfactant especially suitable for wetting, detergency and emulsification.
Nansa HS 80/NPF is used in a wide range of applications, including laundry detergents, surface cleaners and sanitary blocks.
The physical form allows direct incorporation into powders, compressed tablets and blocks.

Nansa HS 80/NPF is an important component of laundry detergent.
Nansa HS 80/NPF is a member of linear alkylbenzenesulfonates, that is, a member of the dodecyl group (C12H25).
Nansa HS 80/NPF is added at position 4 of the benzenesulfonate group.

Nansa HS 80/NPF can exist as six isomers based on the carbon of the dodecyl group (ignoring optical isomers).
Nansa HS 80/NPF, e.g. Derivatives from tetramerized propylene are also known (bottom right) but not as widely used.
Further complicating the definition of commercial materials, sodium dodecylbenzenesulfonate is a component of a compound.

Nansa HS 80/NPF has a mixture of compounds with varying alkyl chain lengths, mainly ranging from C10 to C16.
Nansa HS 80/NPF is considered representative of the entire class of compounds due to its average alkyl carbon number.
Nansa HS 80/NPF has been prepared by many methods.

Most commonly, Nansa HS 80/NPF is alkylated with long chain monoalkenes (eg dodecene) using hydrogen fluoride.
Nansa HS 80/NPF (and related derivatives) are then sulfonated with sulfur trioxide to give the sulfonic acid.
Nansa HS 80/NPF is then neutralized with sodium hydroxide.

Nansa HS 80/NPF surfactants are intended for industrial applications, primarily construction, paint, ink and emulsion polymerization.
Nansa HS 80/NPF acts as intermediates necessary to create specific end-use properties; It is used for foaming and detergent properties of mortar and plaster.
Nansa HS 80/NPF is a dried sodium C10-13 alkylbenzene sulfonate.

Nansa HS 80/NPF is a highly active anionic surfactant, providing excellent emulsification, wetting and detergent properties.
Nansa HS 80/NPF is a class of anionic surfactants consisting of a hydrophilic sulfonate head group and a hydrophobic alkyl.
Nansa HS 80/NPF is a class of anionic surfactants consisting of a hydrophilic sulfonate head group and a hydrophobic head group.

Nansa HS 80/NPF are widely used synthetic detergents and are used in many personal care products (soaps, shampoo, toothpaste, etc.) and household care products (laundry detergent, dishwashing liquid, spray cleaner, etc.).
Nansa HS 80/NPF is used as a surfactant in industrial and household detergents and cleaners.

Nansa HS 80/NPF is used in the chemicals, polymers, photography and textile processing industries;
Nansa HS 80/NPF is also used in photochemicals and building materials.
Nansa HS 80/NPF is a class of surfactants in which alkylbenzene sulfonates are the anionic moiety and sodium is the anionic moiety.

The cationic moiety is basically anionic surfactant.
Since Nansa HS 80/NPF is a surfactant, it is used for cleaning purposes.
Nansa HS 80/NPF can react with both soft water and hard water.

Nansa HS 80/NPF is a rust preventive additive synthesized by sulfonation and neutralization of heavy alkyl benzene, and its emulsion performance is good.
Nansa HS 80/NPF, emulsified cutting oil, can be combined with other additives to be formulated in the wire cutting process.
Nansa HS 80/NPF acts as a surfactant in the ionic self-assembly reaction of cyclophan.

Nansa HS 80/NPF is an ionic surfactant.
Nansa HS 80/NPF is used to stabilize the dispersions of graphene nanoflakes (GNFs) during liquid preparation.
Nansa HS 80/NPF can also individually suspend single-walled carbon nanotubes in aqueous medium and also give well-resolved spectral properties.

Nansa HS 80/NPF is used to manufacture amperometric biosensors for glucose.
Nansa HS 80/NPF is a substituted aromatic compound.
Nansa HS 80/NPF is used in consumer products (such as laundry detergent), chemical synthesis and agriculture.

Nansa HS 80/NPF is a white to light yellow flake, granule or powder.
Nansa HS 80/NPF is water soluble.
Nansa HS 80/NPF urgent steps must be taken to limit its spread to the environment.

Nansa HS 80/NPF is used as a synthetic detergent.
Nansa HS 80/NPF is a yellow oil capable of forming strong flake-like crystals in hexagonal or rhombic shape.
Nansa HS 80/NPF has micro-toxicity and has been recognized as a safe chemical by the international safety organization.

Nansa HS 80/NPF can be used to clean fruit and tableware.b
Nansa HS 80/NPF is sodium alkylbenzene sulphonate powder based on a predominately straight chain C10-13 alkylbenzene (dodecylbenzene).
Nansa HS 80/NPF is a high active anionic surfactant particularly suited to provide wetting, detergency and emulsification in a wide range of applications, including laundry detergents, surface cleaners and hygienic blocks.

The physical form allows direct incorporation into powders, compressed tablets and blocks.
Nansa HS 80/NPF acts as a hydrotrope and can be used to increase the solubility of other compounds.
Nansa HS 80/NPF can react with both soft water and hard water.

Nansa HS 80/NPF, emulsified cutting oil, can be combined with other additives to be formulated in the wire cutting process.
Nansa HS 80/NPF acts as a surfactant in the ionic self-assembly reaction of cyclophan.
Nansa HS 80/NPF is an ionic surfactant.

Nansa HS 80/NPF was used to stabilize the dispersions of graphene nanoflakes (GNFs) during the preparation of the liquid.
Nansa HS 80/NPF can be used for cleaning fruit and tableware.
Nansa HS 80/NPF used in detergents has a branched chain structure (ABS) and a linear structure (LAS).

Nansa HS 80/NPF has a significant effect on granular contamination, protein contamination and oil contamination.
Nansa HS 80/NPF is better for removing granular contamination from natural fibers
Nansa HS 80/NPF, together with non-ionic surfactants, increases the cloud point of the solution and provides a clear liquid.

Provides additional control over foaming properties and performance at higher temperatures.
Nansa HS 80/NPF can also be used to reduce the viscosity of concentrated surfactants and formulations.
Nansa HS 80/NPF is a hydrotrope, solubilizer, coupling agent, cloud point depressant, viscosity reducer, anti-caking agent in powder form.

Nansa HS 80/NPF is used as coupling agents to dissolve water-insoluble and often incompatible functional components.
Nansa HS 80/NPF is used to dissolve complex formulations in water.
Nansa HS 80/NPF provides functions to stabilize solutions, change viscosity and cloud point, limit phase separation at low temperature.

Nansa HS 80/NPF is an amphiphilic substance consisting of both hydrophilic and hydrophobic functional groups.
The hydrophobic part of the molecule is an apolar segment substituted with benzene.
Nansa HS 80/NPF, polar portion of SODIUM CUMEN SULFONATE is an anionic sulfonate group accompanied by a counterion.

Nansa HS 80/NPF is produced by sulfonation of an aromatic hydrocarbon solvent (cumene).
The resulting aromatic Nansa HS 80/NPF is neutralized using a suitable base (eg sodium hydroxide) to produce the sulfonate or hydroxide.
Nansa HS 80/NPF is a 'pure' substance but is typically produced and transported at a level of 90-95% as granular solids.

Nansa HS 80/NPF is an anionic surfactant used in liquid and powder detergent formulations, heavy-duty cleaners, and water.
Nansa HS 80/NPF are prepared industrially by the sulfonation of linear alkylbenzenes (LABs), which can themselves be prepared in several ways.
In the most common Nansa HS 80/NPF is alkylated by long chain monoalkenes (e.g. dodecene) using hydrogen fluoride as a catalyst

The purified dodecylbenzenes (and related derivatives) are then sulfonated with sulfur trioxide to give the Nansa HS 80/NPF.
Nansa HS 80/NPF is subsequently neutralized with sodium hydroxide.
Nansa HS 80/NPF acts as a solubilizing agent, coupling agent and cloud point depressant.

This part of the name indicates the presence of a benzene ring (a six-membered carbon ring with alternating double bonds) that is sulfonated.
Nansa HS 80/NPF usually refers to the presence of a sulfonic acid group (SO3H) in the molecule.

Melting Point: >300 °C
Color: White to yellow
Form: Solid
Solubility: Solubility in water
LogP: 0,45
Exact Mass: 349.18133527
Monoisotopic Mass: 349.18133527
Topological Polar Surface Area: 51.8 Ų

Nansa HS 80/NPF is used in various applications due to its viscosity reducing properties.
Nansa HS 80/NPF is used as a coupling agent, solubilizer and anti-caking agent in powder detergents.
Nansa HS 80/NPF supports compatibility between various chemicals found in multi-component systems.

The use of chemicals in a wide variety of shampoos and dishwashing detergents is expected to boost the Nansa HS 80/NPF market.
Nansa HS 80/NPF is a hydrotope compound consisting of a hydrophilic portion and a hydrophobic portion, similar to surfactant.
Nansa HS 80/NPF has several advantages.

Nansa HS 80/NPF increases the solubility of less soluble organic substances; lowers the cloud point of the aqueous formula.
Nansa HS 80/NPF is used as a solubilizer and cloud point suppressant in wax cleaners, air mist piercing, laundry washing.
Nansa HS 80/NPF are a class of anionic surfactants, consisting of a hydrophilic sulfonate head-group and a hydrophobic alkylbenzene tail-group.

Nansa HS 80/NPF, they are one of the oldest and most widely used synthetic detergents and may be found in numerous personal-care products (soaps, shampoos, toothpaste etc.) and household-care products (laundry detergent, dishwashing liquid, spray cleaner etc.).
They were introduced in the 1930s in the form of branched Nansa HS 80/NPF.

Nansa HS 80/NPF is a water-soluble compound that is widely used in various fields, including medical, environmental, and industrial research.
Nansa HS 80/NPF is a versatile compound that has a wide range of applications due to its unique chemical structure and biological activity.

Uses
Nansa HS 80/NPF is used as a resin dispersant, felt detergent and deinking agent in the papermaking industry.
Nansa HS 80/NPF is used as an osmotic degreaser in the leather industry.
Nansa HS 80/NPF is used as an anti-blocking agent in the fertilizer industry.

Nansa HS 80/NPF is used in the cement industry as a gasifier or separately or in combination with components.
Nansa HS 80/NPF creates a stable dispersion system or emulsion that increases the surface tension between the various components in the emulsion.
Nansa HS 80/NPF has hydrophilic groups and lipophilic groups in its molecule.

Nansa HS 80/NPF is collected at the oil/water border.
Nansa HS 80/NPF can also reduce the interfacial tension and reduce the energy required to form the emulsion.
As a kind of anionic surfactant, Nansa HS 80/NPF has good surface activity and strong hydrophilicity.

Nansa HS 80/NPF effectively reduces oil and water surface tension due to emulsification.
Nansa HS 80/NPF is sodium alkylbenzene sulfonate powder based mainly on straight chain C10-13 alkylbenzene.
Nansa HS 80/NPF is a highly active anionic surfactant especially suitable for wetting, detergency and emulsification.

It has a wide range of applications, including laundry detergents, surface cleaners and sanitary blocks.
Nansa HS 80/NPF is a series of organic compounds with the formula C12H25C6H4SO3Na.
Nansa HS 80/NPF is a colorless salt with beneficial properties as a surfactant.

Nansa HS 80/NPF is usually produced as a mixture of related sulfonates.
Nansa HS 80/NPF is an important component of laundry detergent.
Nansa HS 80/NPF is considered representative of the entire class of compounds due to its average alkyl carbon number.

Nansa HS 80/NPF has been prepared by many methods.
Nansa HS 80/NPF is then neutralized with sodium hydroxide.
Nansa HS 80/NPF surfactants are intended for industrial applications, primarily construction, paint, ink and emulsion polymerization.

Nansa HS 80/NPF is a dried sodium C10-13 alkylbenzene sulfonate.
Nansa HS 80/NPF is a highly active anionic surfactant, providing excellent emulsification, wetting and detergent properties.
Nansa HS 80/NPF is a class of anionic surfactants consisting of a hydrophilic sulfonate head group and a hydrophobic alkyl.

Nansa HS 80/NPF is a class of anionic surfactants consisting of a hydrophilic sulfonate head group and a hydrophobic head group.
Nansa HS 80/NPF are widely used synthetic detergents and are used in many personal care products (soaps, shampoo, toothpaste, etc.) and household care products (laundry detergent, dishwashing liquid, spray cleaner, etc.).
Nansa HS 80/NPF is used as a surfactant in industrial and household detergents and cleaners.

Nansa HS 80/NPF is used in the chemicals, polymers, photography and textile processing industries;
Nansa HS 80/NPF is also used in photochemicals and building materials.
Nansa HS 80/NPF is a class of surfactants in which alkylbenzene sulfonates are the anionic moiety and sodium is the anionic moiety.

The cationic moiety is basically anionic surfactant.
Nansa HS 80/NPF is used in the following products: polymers, coating products, fillers, putties, plasters, modelling clay, paper chemicals and dyes and adhesives and sealants.
Nansa HS 80/NPF is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment, building & construction work and formulation of mixtures and/or re-packaging.

Nansa HS 80/NPF is used for the manufacture of: rubber products, pulp, paper and paper products and plastic products.
Release to the environment of Nansa HS 80/NPF can occur from industrial use: in processing aids at industrial sites, as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture and in the production of articles.

Nansa HS 80/NPF are often used in detergents and cleaning products due to their ability to lower the surface tension of water and enhance the removal of dirt, grease, and stains.
Nansa HS 80/NPF can act as emulsifiers and dispersants, helping to mix immiscible substances and stabilize emulsions in products like paints, coatings, and cosmetics.

Nansa HS 80/NPF can be used in dyeing and finishing processes in the textile industry, improving the dye absorption and colorfastness of fabrics.
Nansa HS 80/NPF are used as additives in lubricating oils and drilling fluids to improve their performance and stability under extreme conditions.
Nansa HS 80/NPF can be used in water treatment processes to remove heavy metals and other contaminants from industrial wastewater.

Nansa HS 80/NPF can be used as intermediates in the synthesis of pharmaceuticals and agrochemicals.
Nansa HS 80/NPF is used to modify ion exchange resins for applications such as water softening and purification.
Nansa HS 80/NPF is used in biological research as labeling agents or markers due to their fluorescent properties.

Safety
Nansa HS 80/NPF, especially those with surfactant properties, might cause skin or eye irritation upon contact.
They could also lead to allergic sensitization in some individuals.
Depending on the specific compound, there might be concerns about acute or chronic toxicity.

Ingestion, inhalation, or absorption through the skin of certain Nansa HS 80/NPF could potentially cause harm.
Nansa HS 80/NPF might have negative effects on aquatic ecosystems due to their surfactant properties, which can disrupt surface tension and affect aquatic organisms.
The extent of environmental impact would depend on factors like concentration and persistence in the environment.

The flammability of a Nansa HS 80/NPF would depend on its chemical structure.
Some organic compounds, including those containing carbon and hydrogen, can be flammable under certain conditions.

Synonyms
Tetrapropylenebenzyl sulfonate
Jadinol PU
Neogen R
Sodium tetrapropylbenzene sulfonate
11067-82-6
Merpisap PD82
TPBS
Nansa HS 55
EINECS 234-289-1
Sodium tetrapropylenebenzenesulphonate
Tetrapropylenebenenesulphonate, sodium salt
Benzenesulfonic acid, tetrapropylene-, sodium salt
sodium 2-dodecylbenzenesulfonate 3-dodecylbenzenesulfonate 4-dodecylbenzenesulfonate
Benzenesulfonic acid, tetrapropylene-, (3R-(3alpha,3aalpha,4beta,4abeta,7abeta,8alpha,9abeta))-
trisodium;2-dodecylbenzenesulfonate;3-dodecylbenzenesulfonate;4-dodecylbenzenesulfonate
AVWQQPYHYQKEIZ-UHFFFAOYSA-K
DTXSID601016230
AKOS040754173
LS-32078
Q15718771
NANSA HS 80/S
DESCRIPTION:

NANSA HS 80/S is dried sodium C10-13 alkylbenzene sulfonate.
NANSA HS 80/S is a high active anionic surfactant particularly suited to provide wetting, detergency and emulsification in a wide range of applications, including laundry detergents, surface cleaners and hygienic blocks.
The physical form allows direct incorporation into powders, compressed tablets and blocks.

CAS No: 25155-30-0
INCI-NAME: Sodium Dodecylbenzene Sulfonate
Formula: C18H30O3S.Na

NANSA HS 80 / S is a dried sodium C10-13 alkylbenzene sulfonate.
NANSA HS 80 / S is highly active anionic surfactant, provides excellent emulisfication, wetting and detergent properties to a wide range of applications.
Sodium Dodecylbenzene Sulfonate ( contains Phosphate) has 80% active powder.
NANSA HS 80 / S is Non-vegetable.

NANSA HS 80 / S is Primary anionic surfactant.
NANSA HS 80 / S has Excellent foaming and detergency properties.
NANSA HS 80 / S is Chemically stable in acidic and alkaline conditions.



USE AND MANUFACTURING OF NANSA HS 80 / S
NANSA HS 80 / S is Used as textile printing and dyeing auxiliary
NANSA HS 80 / S is used as silk printing, penetration and degumming refining auxiliary
GB276-96 stipulates as processing auxiliary for food industry.
NANSA HS 80 / S is Anionic surfactant.
NANSA HS 80 / S has excellent foaming power and detergency.

Because of its low production cost and good performance, NANSA HS 80 / S has a wide range of uses.
NANSA HS 80 / S is the most used synthetic surfactant for household detergents.
NANSA HS 80 / S also produces some inorganic salts such as magnesium and calcium and organic amine salts such as triethanolamine.

NANSA HS 80 / S has excellent emulsifying properties and is an important part of mixed emulsifiers for various pesticides.
Benzene can be condensed with α-olefin under aluminum trichloride catalyst, and the condensed liquid can be washed with alkali and water, and then distilled to recover benzene, and vacuum distillation can obtain refined alkylbenzene.
Then it is sulfonated with fuming sulfuric acid and neutralized with white ash (in 2 times the amount of ethanol) to obtain calcium dodecylbenzene sulfonate


CHEMICAL AND PHYSICAL PROPERTIES OF NANSA HS 80/S:
PSA: 65.58000
XLogP3: 6.13490
Appearance:
white or light yellow flakes
Density: 1.02 g/cm3
Melting Point: >300 °C
Toxicity: LD50 in mice: 2 g/kg orally; 105 mg/kg i.v. (Hopper)
Molecular Weight:
348.47600
Exact Mass:
348.17400
HScode:
3402110000





SAFETY INFORMATION ABOUT NANSA HS 80/S:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product




SYNONYMS OF NANSA HS 80/S:
Benzenesulfonic acid,dodecyl-,sodium salt (1:1);
Benzenesulfonic acid,dodecyl-,sodium salt;
Sodium laurylbenzenesulfonate;
Stepan DS 60;
Ultrawet 1T;
Marlon A 350;
Sodium dodecylphenylsulfonate;
Sulframin 85;
Marlon A;
Dodecylbenzenesulfonic acid sodium salt;
Maranil;Marlon A 375;
Nacconol 35SL;
Siponate DS 10;
Trepolate F 40;
Conoco C 550;
KB (surfactant);
Nansa SL;
Santomerse Me;
Merpisap AP 90P;
Nansa SS;
Trepolate F 95;
Nansa HS 80;
Deterlon;
Ultrawet 99LS;
Sulfuril 50;F 90;
Elfan WA Powder;
Sandet 60;
Steinaryl NKS 50;
Sinnozon;
Nansa HS 85S;
C 550;
KB;
HS 85S;
Nansa HF 80;
Arylan SBC;
Marlon 375A;
X 2073;
Conco AAS 35H;
Neopelex 05;
Richonate 40B;
DS 60;
Pelopon A;
Sulframin 1240;
Richonate 1850;
35SL;
Calsoft L 40;
Calsoft F 90;
SDBS;
Alkanate DC;
Sulfaril Paste;
Steinaryl NKS 100;
Siponate DS 4;
Siponate LDS 10;
Nestapone;
Nansa 1260;
Marlon 375;
Neopelex F 60;
Abeson NAM;
Emulin B 22;
Neopelex 6;
Bio-Soft D 40;
Neogen SC;
Nissan Newrex R;
Conco AAS 35;
Reworyl NKS 50;
Elfan WA 35;
Neopelex 25;
Elfan WA 50;
MB-VR;
Marlon A 396;
Neopelex F 25;
Witconate 1238;
Sulframin 40;
Nacconol 40F;
Nansa HS 80S;
Conco AAS 45S;
Newrex R;
A 1-1575;
Nansa 1106;
Maranil A 55;
Neopelex 6E;
Liponox LE 110;
Nissan Newrex H;
Vista C 550;
Witconate 1250;
Conco AAS 40S;
Bio-Soft D 35X;
Stepantan DS 40;
Phenyl Sulfonate HSR;
Deterlon A;
Polystep A 15;
Nansa HS 80SA;
Bio-Soft LAS 40S;
Witconate 60B;
Nissan Newrex F;
Newrex Powder F;
F 90 (sulfonic acid);
Nansa SSA 055;
Newrex T;
1323-13-3;
11114-21-9;
12068-21-2;
12627-25-7;
12676-70-9;
18618-53-6;
19327-14-1;
28675-02-7;
37334-89-7;
39316-39-7;
39386-98-6;
39405-16-8;
52624-37-0;
56590-39-7;
57762-50-2;
58517-33-2;
60328-33-8;
63530-22-3;
68445-25-0;
71244-85-4;
76483-01-7;
82028-94-2;
82785-43-1;
83203-33-2;
83652-87-3;
83652-88-4;
83652-89-5;
88495-86-7;
90452-02-1;
94187-92-5;
122390-78-7;
128452-17-5;
138362-06-8;
142986-60-5;
147035-77-6;
167163-39-5;
170006-86-7;
177645-67-9;
178900-97-5;
189201-38-5;
254117-47-0;
295348-93-5;
312629-70-2;
352212-18-1




NANSA HS 85 / NPF
DESCRIPTION:
NANSA HS 85 / NPF is sodium alkylbenzene sulphonate powder based on a predominately straight chain C10-13 alkylbenzene (dodecylbenzene).
NANSA HS 85 / NPF is a high active anionic surfactant particularly suited to provide wetting, detergency and emulsification in a wide range of applications, including laundry detergents, surface cleaners and hygienic blocks.
The physical form allows direct incorporation into powders, compressed tablets and blocks.


CAS number: 85117-50-6
EC number: 285-600-2
PHYSICAL AND CHEMICAL PROPERTIES OF NANSA HS 85 / NPF:
Appearance:
Granules. Dusty powder. Solid
Colour Beige.
Odour Odourless.
pH pH (concentrated solution): 9 - 11 pH (diluted solution): 9 @ 1%
Relative density 400 - 500 @ @ 20˚C°C
Solubility(ies) Soluble in water.


SAFETY INFORMATION ABOUT NANSA HS 85 / NPF:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product



NANSA HS 85/NPF

Nansa HS 85/NPF is a versatile chemical compound.
Nansa HS 85/NPF is a sodium alkylbenzene sulphonate powder.
The primary constituent of Nansa HS 85/NPF is straight-chain C10-13 alkylbenzene, specifically dodecylbenzene.
Nansa HS 85/NPF is classified as a high-active anionic surfactant.



APPLICATIONS


Nansa HS 85/NPF is widely used in laundry detergents to enhance their cleaning power.
Nansa HS 85/NPF effectively removes dirt, stains, and grime from clothing and fabrics.

Nansa HS 85/NPF is a key ingredient in many liquid laundry detergents.
Nansa HS 85/NPF is used in powder laundry detergents as well, improving their performance.
Nansa HS 85/NPF is used in the formulation of various surface cleaners for household and industrial use.

Nansa HS 85/NPF helps break down and remove grease, oils, and residues from surfaces.
Nansa HS 85/NPF is used in dishwashing detergents to enhance their degreasing capabilities.

Nansa HS 85/NPF is known for its ability to create stable emulsions of oil and water.
Nansa HS 85/NPF is incorporated into hygienic blocks, which are used for cleaning and deodorizing toilet bowls and urinals.

Nansa HS 85/NPF provides wetting properties in various cleaning solutions, ensuring even coverage on surfaces.
Nansa HS 85/NPF is used in the production of compressed tablets for dishwashing and laundry.
Nansa HS 85/NPF enhances the foaming and cleaning performance of detergents.

Nansa HS 85/NPF is employed in the formulation of industrial cleaners for equipment and machinery.
Nansa HS 85/NPF is used in car wash detergents to help remove road grime and dirt from vehicles.
Nansa HS 85/NPF finds applications in the manufacturing of degreasers and heavy-duty cleaning solutions.

Nansa HS 85/NPF contributes to the effectiveness of degreasing and descaling agents.
Nansa HS 85/NPF is used in the production of multi-purpose household cleaners.
Nansa HS 85/NPF helps maintain the stability of cleaning product formulations.

Nansa HS 85/NPF is employed in the formulation of degreasers for kitchen appliances and surfaces.
Nansa HS 85/NPF plays a role in the emulsification of fats and oils in industrial settings.
Nansa HS 85/NPF is added to cleaning solutions for floors, walls, and countertops.
Nansa HS 85/NPF can be used in the preparation of cleaning wipes and wet wipes.
Nansa HS 85/NPF is found in various formulations for institutional and commercial cleaning.

Nansa HS 85/NPF assists in achieving thorough and efficient cleaning results.
Nansa HS 85/NPF is a versatile ingredient, finding applications in a wide range of cleaning and detergent products.

Nansa HS 85/NPF is used in industrial degreasing processes to remove oil and grease from machinery parts.
Nansa HS 85/NPF aids in breaking down and dispersing stubborn residues on surfaces.
Nansa HS 85/NPF is incorporated into carpet cleaning solutions to help remove stains and dirt from carpets and upholstery.
Nansa HS 85/NPF is utilized in the production of concentrated liquid dishwashing detergents.

Nansa HS 85/NPF contributes to the formulation of high-performance glass and window cleaners.
Nansa HS 85/NPF is found in the manufacturing of specialty cleaning products for the food industry.

Nansa HS 85/NPF is used in the formulation of kitchen degreasers for both household and commercial use.
Nansa HS 85/NPF is added to floor cleaners to improve their ability to remove dirt and grime from various flooring types.

Nansa HS 85/NPF assists in the emulsification of oils in automotive engine cleaning products.
Nansa HS 85/NPF can be found in handwashing dish soap formulations.
Nansa HS 85/NPF is used in the production of disinfectant cleaners for surfaces.

Nansa HS 85/NPF helps in the removal of soap scum and mineral deposits in bathroom cleaners.
Nansa HS 85/NPF is employed in the formulation of mold and mildew removers for household and industrial applications.

Nansa HS 85/NPF is utilized in the production of all-purpose spray cleaners for convenience.
Nansa HS 85/NPF is added to laundry pre-treatment products designed to target tough stains.

Nansa HS 85/NPF is used in the formulation of stain removers for fabrics and carpets.
Nansa HS 85/NPF plays a role in the production of cleaning solutions for appliances like stovetops and ovens.
Nansa HS 85/NPF can be found in the composition of vehicle degreasing and cleaning products.

Nansa HS 85/NPF is employed in the creation of surface sanitizers and disinfectants.
Nansa HS 85/NPF assists in achieving streak-free shine in glass and mirror cleaning solutions.

Nansa HS 85/NPF is added to floor stripping and waxing products for industrial and commercial floor maintenance.
Nansa HS 85/NPF is used in the formulation of rust and corrosion removers.

Nansa HS 85/NPF can be found in the production of pool and spa cleaning solutions.
Nansa HS 85/NPF helps to create effective cleaning formulations for outdoor surfaces and decks.
Nansa HS 85/NPF's versatile properties make it a valuable component in various cleaning and maintenance products across industries.



DESCRIPTION


Nansa HS 85/NPF is a versatile chemical compound.
Nansa HS 85/NPF is a sodium alkylbenzene sulphonate powder.

The primary constituent of Nansa HS 85/NPF is straight-chain C10-13 alkylbenzene, specifically dodecylbenzene.
Nansa HS 85/NPF is classified as a high-active anionic surfactant.
Nansa HS 85/NPF is particularly well-suited for providing wetting properties.

Nansa HS 85/NPF is also known for its excellent detergency characteristics.
Nansa HS 85/NPF has strong emulsification capabilities.

Nansa HS 85/NPF finds application in a wide range of products.
This includes laundry detergents.

Nansa HS 85/NPF is used in surface cleaners as an effective cleaning agent.
Nansa HS 85/NPF is also used in the production of hygienic blocks.
Nansa HS 85/NPF is available in powder form.

Its physical form makes it easy to incorporate into various product formulations.
Nansa HS 85/NPF is highly active, meaning it can be used in relatively small quantities to achieve the desired effects.
Nansa HS 85/NPF helps to break down and remove dirt, stains, and grease from surfaces.
Nansa HS 85/NPF is suitable for both household and industrial cleaning applications.

Its emulsification properties make it useful for formulating products like dishwashing liquids.
Nansa HS 85/NPF enhances the dispersion of oil and grease in water-based solutions.
Nansa HS 85/NPF is compatible with other common detergent ingredients.

Nansa HS 85/NPF contributes to the foaming and cleaning performance of detergent formulations.
Nansa HS 85/NPF can be used in dry powder laundry detergents.

Nansa HS 85/NPF is also effective in concentrated liquid detergents.
Nansa HS 85/NPF helps maintain the stability of detergent formulations.

Nansa HS 85/NPF can be used in both manual and automatic washing machines.
Nansa HS 85/NPF is known for its effectiveness in removing tough stains and providing a high level of cleanliness.



PROPERTIES


Chemical Composition: Nansa HS 85/NPF primarily consists of straight-chain C10-13 alkylbenzene, specifically dodecylbenzene.
Chemical Formula: The specific chemical formula may not be disclosed for proprietary commercial products.
Physical Form: It is available in powder form.
Ionic Nature: Nansa HS 85/NPF is an anionic surfactant, meaning it carries a negative charge when dissolved in water.
Solubility: It is soluble in water, which is important for its use in aqueous cleaning solutions.
Wetting Properties: Nansa HS 85/NPF is known for its excellent wetting capabilities, ensuring thorough coverage of surfaces.
Detergency: It possesses strong detergency properties, aiding in the removal of dirt, stains, and grease.
Emulsification: Nansa HS 85/NPF is effective at emulsifying oils and grease, allowing them to mix with water-based solutions.
Foaming: It contributes to the foaming properties of cleaning products, creating lather in detergents and cleaners.
Compatibility: The chemical is compatible with a range of other detergent ingredients and additives.
Stability: It helps maintain the stability of cleaning product formulations, preventing separation or degradation.
Cleaning Performance: NANSA HS 85/NPF is recognized for its ability to provide high-quality cleaning and stain removal.



FIRST AID


Inhalation:

If inhaled, move the affected person to an area with fresh air immediately.
Allow the person to rest in a comfortable position and keep them warm.
If breathing difficulties persist or if there are signs of respiratory distress, seek immediate medical attention.


Skin Contact:

In case of skin contact, promptly remove contaminated clothing.
Wash the affected skin area gently but thoroughly with plenty of water and mild soap.
If skin irritation, redness, or rash develops, seek medical attention.
If the chemical is in powder form, carefully brush off excess powder before washing with water.


Eye Contact:

If the chemical comes into contact with the eyes, immediately rinse the affected eye(s) gently with lukewarm, running water for at least 15 minutes. Hold the eyelids open to ensure thorough rinsing.
Seek immediate medical attention if eye irritation or redness persists or if there is any discomfort.


Ingestion:

If Nansa HS 85/NPF is ingested, do not induce vomiting unless directed to do so by medical professionals.
Rinse out the mouth with water if the person is conscious and able to do so.
Seek immediate medical attention or contact a poison control center.
Provide the medical personnel with detailed information about the ingested substance.


In Case of Spills or Leaks:

Avoid direct contact with the spilled material.
Wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and protective clothing.
Contain the spill if possible, using absorbent materials like sand, vermiculite, or commercial spill control agents.
Carefully collect the spilled material and place it in suitable containers for disposal.
Ventilate the area to disperse any fumes or vapors.
Dispose of the spilled material and contaminated items in accordance with local regulations and guidelines.