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REWOPAL PEG 6000 DS A MB
Rewopal PEG 6000 DS A MB is an extremely effective additive for difficult to thicken surfactant systems.
Rewopal PEG 6000 DS A MB is a thickening agent.



CAS Number: 9005-08-7
EINECS: Polymer Exempt
MDL Number: MFCD00081839
INCI Name: PEG-150 Distearate
Chem/IUPAC Name: Poly (oxy-1,2-ethanediyl),. alpha. -(1-oxooctadecyl)-. omega. -[(1-oxooctadecyl)oxy]-
Molecular Formula : C19H40O4



Macrogol 6000, Polyethylenglycol 6000, Polyethylenglykol 6000 Distearat, Polyoxyethylen(150), Polyoxyethylen(150)distearat, THOX P-6000 DS, PEG-150 DISTEARATE, PEG-150 DISTEARATE [II], PEG-150 DISTEARATE [INCI], POLYETHYLENE GLYCOL 6000 DISTEARATE, POLYOXYL 150 DISTEARATE, UNIPEG-6000 DS, PEG-150 DISTEARATE, POE (150) DISTEARATE, KESSCO PEG 6000 DISTEARATE, Glycols,polyethylene, distearate (8CI), Stearic acid, diester with polyethylene glycol(8CI), 62S, 62S (lubricant), Aculyn 60, Atlas G 1821, CDS 400, CDS 6000P, CRL1095, Cithrol 10DS, Cithrol 4DS, Cithrol 60DS, Cutina TS, Cyclo PEG (400)DS, Dispeg 200, EL 1821, Emalex 200di-S, Emalex 600di-S, Emalex di-S, Emanon 3299, Emanon 3299R, Emanon 3299RV, Emanon 3299V, Emerest 2642, Emerest 2712, Emulgen3299, Emulmin 862, Estol 3734, Estol EO 4DS3724, Eumulgin EO 33, Gelucire55/18, Genapol TS Powder, Hetoxamate 6000, Hetoxamate 6000DS, Hetoxamate 6000DSSpecial, Ionet DS 1000, Ionet DS 300, Ionet DS 400, Ionet DS 4000, Kessco PEG400DS, Kessco PEG 6000DS, Lionon DT 600S, Lipal 15DS, Lipal 400DS, Lipopeg 4DS, Lipopeg 6000DS, Mapeg 1540DS, Mapeg 400DS, Mapeg 6000DS, Mazol 6000DS, NikkolCDS 6000P, Nissan Nonion DS 60HN, Noigen DS 601, Nonex 80, Nonion DS 60HN, Nonisol 300, PEG 150 distearate, PEG 1540 distearate, PEG 1540DS, PEG 6000distearate, PEG 6000DS, PEG 8 distearate, PEG distearate, PEG-2 Distearate, PEG-20 Distearate, Pegnol PDS 60, Pegosperse 400DS, Pionin D 2410D, Poly(oxyethylene) distearate, Polyethylene glycol dioctadecanoate, Polyethyleneglycol distearate, Polyethylene glycol distearoyl ester, Polyethylene glycolstearic acid diester, Polyethylene oxide distearate, Rewopal PEG 6000DS, Ritapeg 150DS, S 1009, S 1013, Stabogel, Polyethylene glycol distearate, PEG400 Distearate, heptadecanoic acid - ethane-1,2-diol (1:1), PEG 6000 Distearate Powder, PEG 6000 Distearate, Unipeg 6000DS, Lipopeg 6000 DS, Protamate 6000 DS, T/N: Lumulse 602-S, T/N: Acipol Di 15018 B, Polyethylene glycol distearate, Polyoxyethylene Distearate ester, POE(150) Distearate, Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-[(1-oxooctadecyl)oxy]-



Rewopal PEG 6000 DS A MB is a hydrophilic surfactant thickening agent.
Rewopal PEG 6000 DS A MB is an extremely effective additive for difficult to thicken surfactant systems.
Rewopal PEG 6000 DS A MB is a thickening agent.


Rewopal PEG 6000 DS A MB offers a distinctive viscosity modifying effect.
Rewopal PEG 6000 DS A MB is an extremely effective additive for difficult to thicken surfactant systems.
Rewopal PEG 6000 DS A MB is a polyethylene glycol diester of stearic acid.


Rewopal PEG 6000 DS A MB is an off-white flake
Rewopal PEG 6000 DS A MB is a white to yellowish pellets.
Rewopal PEG 6000 DS A MB is a hydrophilic emulsifier; thickener.


Rewopal PEG 6000 DS A MB is a polyethylene glycol diester of stearic acid.
Rewopal PEG 6000 DS A MB is an off-white flake
Rewopal PEG 6000 DS A MB is a white to yellowish pellets.


This thickening agent, Rewopal PEG 6000 DS A MB, has garnered appreciation for its widespread use in personal care products, cosmetics, paints, and dyes.
Rewopal PEG 6000 DS A MB is produced by the esterification of stearic acid which is derived from palm kernel oil or other vegetable oils.
Rewopal PEG 6000 DS A MB is an efficient thickening agent for shampoos, body washes or foam baths.
Even at low levels, Rewopal PEG 6000 DS A MB results in a high viscosity modifying effect.


Rewopal PEG 6000 DS A MB is polyethylene glycol diester of stearic acid.
Rewopal PEG 6000 DS A MB is a thickening agent.
Rewopal PEG 6000 DS A MB is easy to handle and shows distinctive viscosity modifying effects.


Rewopal PEG 6000 DS A MB is an ester made from the reaction of vegetable-derived triple-pressed grade stearic acid and a defined high molecular weight polyethylene glycol.
Rewopal PEG 6000 DS A MB is a white to off-white powder.


Rewopal PEG 6000 DS A MB is an ester made from the reaction of vegetable-derived triple-pressed grade stearic acid and a defined high molecular weight polyethylene glycol.
Rewopal PEG 6000 DS A MB is particularly effective for the thickening of clear, mild, amphoteric-containing surfactant systems, such as shampoos, body washes, bubble baths, baby baths, vapor baths, and shower gels.


Rewopal PEG 6000 DS A MB is an emulsifying agent (O/W) and thickener (aqueous).
Rewopal PEG 6000 DS A MB is an ester made from the reaction of vegetable-derived triple-pressed grade stearic acid and a defined high molecular weight polyethylene glycol.


Rewopal PEG 6000 DS A MB is an ester made from the reaction of vegetable-derived triple-pressed grade stearic acid and a defined high molecular weight polyethylene glycol.
Rewopal PEG 6000 DS A MB is a polyether compound that is used in a wide variety of fields including pharmaceutical manufacturing as an excipient and active ingredient.


Rewopal PEG 6000 DS A MB is an ester made from the reaction of vegetable-derived triple-pressed grade stearic acid and a defined high molecular weight polyethylene glycol.
Rewopal PEG 6000 DS A MB is an efficient thickening agent for shampoos, body washes or foam baths.



USES and APPLICATIONS of REWOPAL PEG 6000 DS A MB:
Rewopal PEG 6000 DS A MB is used Skin care (Facial care, Facial cleansing, Body care, Baby care) > Baby care > Baby shampoos,
Toiletries (Shower & Bath, Oral care...) > Shower & bath > Foam bath
Skin care (Facial care, Facial cleansing, Body care, Baby care) > , Facial cleansing > Cleansing lotions & toners, and


Hair care (Shampoos, Conditioners & Styling) > Shampoos.
Rewopal PEG 6000 DS A MB is used in baby shampoos, mild hair shampoos, foam baths, shower shampoos and skin cleansing lotions
Rewopal PEG 6000 DS A MB is used thickening agent for cleansing formulations, especially shampoo, shower and bath preparations.


Rewopal PEG 6000 DS A MB is used Antiperspirants & Deodorants, Baby Care and Cleansing, Face Cleansing, Liquid Soap, Shampoo, and Shower/Bath Products.
Rewopal PEG 6000 DS A MB is a non-ionic surfactant with low irritation to the skin and eyes with excellent thickening power, in addition to acting positively on foam formation and increasing the viscosity response of other surfactants in the formulations.


This thickening agent, Rewopal PEG 6000 DS A MB has garnered appreciation for its widespread use in personal care products, cosmetics, paints, and dyes.
Rewopal PEG 6000 DS A MB is produced by the esterification of stearic acid which is derived from palm kernel oil or other vegetable oils.
Rewopal PEG 6000 DS A MB is an ester made from the reaction of triple pressed stearic acid and polyethylene glycol.


Rewopal PEG 6000 DS A MB is commonly used to thicken mild, amphoteric-containing surfactant systems, such as baby shampoos, lotions, pet shampoos, bubble baths, cleansing products, and hair conditioners.
Rewopal PEG 6000 DS A MB is recommended for baby-, mild hair- & shower shampoos, foam baths and skin cleansing lotions.


The shelf life of Rewopal PEG 6000 DS A MB is 12 months.
Rewopal PEG 6000 DS A MB is particularly effective for the thickening of clear, mild, amphoteric-containing surfactant systems, such as shampoos, body washes, bubble baths, baby baths, vapor baths and shower gels.


Rewopal PEG 6000 DS A MB can also be used to thicken facial scrubs, facial cleansers, body scrubs and shaving foams, and finds application in color cosmetics as an auxiliary emulsifer (HLB ~18.4).
The typical use level of Rewopal PEG 6000 DS A MB is 2 – 4%.


Rewopal PEG 6000 DS A MB is in the form of solid, white to off-white waxy flakes and used as a thickener, emulsifier, solubilizer in cosmetics and personal care products.
Typical concentration of Rewopal PEG 6000 DS A MB is 0.5-50%.


Rewopal PEG 6000 DS A MB is an efficient thickening agent for shampoos, body washes or foam baths.
Even at low levels, Rewopal PEG 6000 DS A MB results in a high viscosity modifying effect.
Rewopal PEG 6000 DS A MB is used in formulations which are difficult to thicken.


Rewopal PEG 6000 DS A MB is used in formulations which are difficult to thicken.
Industry Primarily Used of Rewopal PEG 6000 DS A MB: Cosmetics, Pharmaceuticals, Inks & Coatings
Rewopal PEG 6000 DS A MB is particularly effective for the thickening of clear, mild, amphoteric-containing surfactant systems, such as shampoos, body washes, bubble baths, baby baths, vapor baths, and shower gels.


Rewopal PEG 6000 DS A MB can also be used to thicken facial scrubs, facial cleansers, body scrubs, and shaving foams, and finds application in color cosmetics as an auxiliary emulsifier (HLB ~18.4).
The typical use level of Rewopal PEG 6000 DS A MB is 2 – 4%.


Rewopal PEG 6000 DS A MB is commonly used to thicken mild, amphoteric-containing surfactant systems, such as baby shampoos, baby bath and facial scrubs.
Rewopal PEG 6000 DS A MB is also used in deodorants, facial cleansers, facial color cosmetics, liquid hand soaps, shampoos, shaving products and shower gels/body washes.


Rewopal PEG 6000 DS A MB is commonly used to thicken mild, amphoteric-containing surfactant systems, such as baby shampoos, baby baths, facial scrubs, facial cleansers, body washes, body scrubs and shaving foams.
Rewopal PEG 6000 DS A MB also finds application in color cosmetics as an auxiliary emulsifer/


Due to its low toxicity Rewopal PEG 6000 DS A MB can be used as a lubricating coating for various surfaces in aqueous and non-aqueous environments, a reagent in biochemistry to create very high osmotic pressures, a polar stationary phase for gas chromatography and as a binder.



FUNCTION OF REWOPAL PEG 6000 DS A MB:
Rewopal PEG 6000 DS A MB is commonly used to thicken mild, amphoteric-containing surfactant systems, such as baby shampoos, baby baths, facial scrubs, facial cleansers, body washes, body scrubs and shaving foams.
Rewopal PEG 6000 DS A MB also finds application in color cosmetics as an auxiliary emulsifer (HLB ~18.4).



CHARACTERISTICS OF REWOPAL PEG 6000 DS A MB:
Extremely effective additive for difficult to thicken surfactant
systems.



ADVANTAGES OF REWOPAL PEG 6000 DS A MB:
*easy to handle
*shows distinctive viscosity modifying effects



FEATURES & BENEFITS OF REWOPAL PEG 6000 DS A MB:
*Emulsifying Agent (O/W)
*Thickener (aqueous)



WHAT IS REWOPAL PEG 6000 DS A MB USED FOR?
Rewopal PEG 6000 DS A MB is used mainly as a thickener in products like shampoos, conditioners, shower gels, face washes, hand washes, shaving creams, baby-care products etc.
*Skin care:
Rewopal PEG 6000 DS A MB is used as an emulsifier in creams and lotions
*Hair care:
Rewopal PEG 6000 DS A MB is used as an anti-static agent in conditioners



ORIGIN OF REWOPAL PEG 6000 DS A MB:
Rewopal PEG 6000 DS A MB is produced by the esterification of stearic acid which is derived from palm kernel oil or other vegetable oils.



WHAT DOES REWOPAL PEG 6000 DS A MB DO IN A FORMULATION?
*Emulsifying
*Viscosity controlling



SAFETY PROFILE OF REWOPAL PEG 6000 DS A MB:
Rewopal PEG 6000 DS A MB is designated as safe to be used in products at a concentration of 5.0%.



FUNCTIONS OF REWOPAL PEG 6000 DS A MB:
*Thickener,
*Viscosity Modifier,
*Viscosity Stabilizer



BENEFIT CLAIMS OF REWOPAL PEG 6000 DS A MB:
*Rich Feel



BENEFITS AND USES OF REWOPAL PEG 6000 DS A MB:
Rewopal PEG 6000 DS A MB is used to thicken products like shampoos, conditioners, shower gels, hand washes, shaving creams, etc.
Rewopal PEG 6000 DS A MB is an excellent emulsifier and is usually added to creams and lotions.

Rewopal PEG 6000 DS A MB mixes well with water and oil and enables them to clean dirt and grime from the surface.
Rewopal PEG 6000 DS A MB forms a film on the hair and reduces static and is therefore used in conditioners.
When added to paints and dyes, Rewopal PEG 6000 DS A MB thickens their consistency and emulsifies them.



HOW REWOPAL PEG 6000 DS A MB WORKS?
Rewopal PEG 6000 DS A MB works by acting as a solubilizer for water-insoluble ingredients.
Rewopal PEG 6000 DS A MB reduces the surface tension of the substances and helps form emulsions.



CONCENTRATION AND SOLUBILITY OF REWOPAL PEG 6000 DS A MB:
Rewopal PEG 6000 DS A MB is used at a concentration of 0.5% to 5% of the formulation.
Rewopal PEG 6000 DS A MB is soluble in water and ethanol and is insoluble in vegetable and mineral oil.



HOW TO USE REWOPAL PEG 6000 DS A MB?
Heat Rewopal PEG 6000 DS A MB with other surfactants at 60oC and melt it completely.
Mix this blend into the water phase at 35oC and stir.
Add oil phase and adjust the pH.



FUNCTIONS OF REWOPAL PEG 6000 DS A MB:
Rewopal PEG 6000 DS A MB is an ester made from the reaction of vegetable-derived triple-pressed grade stearic acid and a defined high molecular weight polyethylene glycol.
Rewopal PEG 6000 DS A MB is commonly used to thicken mild, amphoteric-containing surfactant systems, such as baby shampoos, baby baths, facial scrubs, facial cleansers, body washes, body scrubs and shaving foams.



STORAGE OF REWOPAL PEG 6000 DS A MB:
Keep Rewopal PEG 6000 DS A MB container tightly closed.



BENEFITS / APPLICATION OF REWOPAL PEG 6000 DS A MB:
Rewopal PEG 6000 DS A MB is a high molecular weight distearate of polyethyleneglycol that provides excellent properties of thickening to formulations based on surfactants agents.

Rewopal PEG 6000 DS A MB is a differentiated thickener with excellent suavity.
Rewopal PEG 6000 DS A MB can be used in many cosmetic formulations, such as shampoos for adults, for children, foam bath, liquid soaps, etc.

Rewopal PEG 6000 DS A MB is a versatile product that can be used as the unique
thickening agent or even associated to alkanolamides, etoxilated
fatty alcohols, and betaines.

Due to the ethylene oxide groups in its molecule, Rewopal PEG 6000 DS A MB acts improving the viscosity of surfactants usually used in soft formulations.
Therefore, surfactants such as sorbitan monolaurate, sulfosuccinates, and betaines have Rewopal PEG 6000 DS A MB's thickener profile improved.

When associated to etoxilated fatty alcohols Rewopal PEG 6000 DS A MB shows a
special synergy that allows that alkanol amides be partially or totally
substituted.

Rewopal PEG 6000 DS A MB should be added under agitation to the water of formulation – total or part of the water – at 70-80°C.
In cold processing, Rewopal PEG 6000 DS A MB must be previously dissolved before
incorporate it to the formulation.

It is better elaborate an aqueous solution at 10% and heat this solution until 70-80°C or Rewopal PEG 6000 DS A MB can be solubilized in the amide associated to an amphoteric, heating to 65-75°C.
After this step, the cold processing can continue.



MAIN PROPERTIES OF REWOPAL PEG 6000 DS A MB:
*Surfactant
*Viscosity Controller



INDICATIONS OF REWOPAL PEG 6000 DS A MB:
Rewopal PEG 6000 DS A MB can be incorporated into shampoos, children's shampoos, liquid soaps and bubble baths.



PHYSICAL and CHEMICAL PROPERTIES of REWOPAL PEG 6000 DS A MB:
Color: 1 Gard Max
Acid Value: 9.0 Max
Saponification Value: 14 - 20
Hydroxyl Value: 2.5 Max
Appearence: Off-white solid
Moisture: 1.0% Max
pH: 4.0 - 7.0 (@ 3% Solution Distilled)
Boiling Point: 492-497°C
Melting Point: 52-57°C
Hydroxyl Value: 5 max.
Solubility: Soluble in water and ethanol
Insoluble in mineral and vegetable oil
Saponification Value: 165-175 mgKOH/g
Appearance Form: solid
Odor: No data available
Odor Threshold: No data available

pH: No data available
Melting point/freezing point:
Melting point/range: 35 - 37 °C
Initial boiling point and boiling range: No data available
Flash point: > 113,00 °C - closed cup
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Density: No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: No data available

Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Appearance: Flakes/Solid
Color: White to slight yellowish
Acid value: 0 – 9 mg KOH/g
Iodine value: 0 – 1 g I2/100 g
Saponification value: 14 – 25 mg KOH/g
Name: PEG 6000 DISTEARATE
CAS Registry Number: 9005-08-7
Cloud Point: 83C (1% AQ. SOLN.)
Comments: NONIONIC

Density (Specific Gravity)= (25C): 1.075
HLB Number: 18.4
Instrument Name:DIGILAB FTS-40
Melting Point: 55C
Sample Description: OFF-WHITE FLAKES
EINECS: N/A
CAS No.: 9005-08-7
Density: N/A
PSA: 77.76000
LogP: 4.91340
Solubility: N/A
Melting Point: 35-37 °C
Formula: (C2H4O)n.C36H70O3
Boiling Point: 495.3oC at 760 mmHg
Molecular Weight: 332.51900
Flash Point: >230 °F
Transport Information: N/A
Appearance: Solid
Safety: Risk Codes: N/A
Hazard Symbols: N/A



FIRST AID MEASURES of REWOPAL PEG 6000 DS A MB:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water.
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of REWOPAL PEG 6000 DS A MB:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of REWOPAL PEG 6000 DS A MB:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.



EXPOSURE CONTROLS/PERSONAL PROTECTION of REWOPAL PEG 6000 DS A MB:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Safety glasses.
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of REWOPAL PEG 6000 DS A MB:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Recommended storage temperature see product label.



STABILITY and REACTIVITY of REWOPAL PEG 6000 DS A MB:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
no information available


Rezene Ekstraktı
Foeniculum Vulgare Seed Extract ; common fennel seed powder; foeniculum vulgare mill. var. vulgare (mill.) thell. seed powder cas no: 92623-75-1
Rhamnus frangula
rhamnus frangula bark; bark of the buchthorn, frangula alnus, rhamnaceae; bark of the buchthorn, frangula alnus, rhamnaceae; buckthorn bark (rhamnus frangula); buckthorne bark (rhamnus frangula); frangula alnus bark CAS NO: 84625-48-9
RHEOCARE HSP 1180
DESCRIPTION:

RHEOCARE HSP 1180 is a polyacrylamidomethylpropane sulfonic acid homopolymer of acrylamidomethyl-propane sulfonic acid.
RHEOCARE HSP 1180 has been designed to provide cosmetic formulations with a high degree of lubricity both during and after use even at low concentrations.
In this manner, its effect is two-fold.

CAS numbers: 27119-07-9
Chemical description: Polysulfonic acid solution
INCI name(s) Polyacrylamidomethylpropane Sulfonic Acid



First, the consumer perceives an elegant, aesthetically pleasing slip during the application and second, a talc-like residual feel later on.
Additionally, RHEOCARE HSP 1180 will act as an auxiliary-thickening agent particularly in hydro alcoholic systems which are resistant to viscosity build-up.
Furthermore, because RHEOCARE HSP 1180 contains, as part of its molecular structure, sulfonic acid groups, it is soluble in strong acids and strong bases (where it can be effectively neutralized by a host of alkaline cations).

RHEOCARE HSP 1180 is ideally suited for application in creams and lotions, liquid (i.e. roll-ons) antiperspirants, shaving creams, nail polish removers, liquid and bar soaps, after-bath splash, and other areas where lubricious effects and/or viscosity effects are desired.
Aesthetically pleasing slip during application and has a talc-like residual feel later on.
RHEOCARE HSP 1180 is soluble in strong acids.


RHEOCARE HSP 1180 has a lubricious sensation during application and a soft and plush after-feel even at low concentrations.
The anionic polymer is free of preservatives and suitable for cold processing.
RHEOCARE HSP 1180 is ideal for innovative face- and body-care concepts that offer a luxurious sensory experience.

RHEOCARE HSP 1180 is an anionic polymer with high slip/ lubricity for wide range of cosmetic applications, especially hair care.
RHEOCARE HSP 1180 has a lubricious sensation during application and a soft and plush after-feel even at low concentrations.
The anionic polymer is free of preservatives and suitable for cold processing.
RHEOCARE HSP 1180 is ideal for innovative face- and body-care concepts that offer a luxurious sensory experience.

RHEOCARE HSP 1180 is a sensory modifier and anionic conditioning agent.
RHEOCARE HSP 1180 offers plush, lubricity and soft after-feel.
RHEOCARE HSP 1180 is cold-processable, suitable for EO-free formulations and does not contain preservatives.

RHEOCARE HSP 1180 is used in antiperspirants, deodorants, after-sun and body-, face & color care products.
RHEOCARE HSP 1180 is also used in face cleansing, personal care wipes, sun protection and self-tanning products.

USES OF RHEOCARE HSP 1180:
RHEOCARE HSP 1180 is a polyacrylamidomethylpropane sulfonic acid homopolymer of acrylamidomethyl -propane sulfonic acid.
RHEOCARE HSP 1180 has been designed to provide cosmetic formulations with a high degree of lubricity both during and after use even at low concentrations.
In this manner, its effect is two-fold.

First, the consumer perceives an elegant, aesthetically pleasing slip during application and second, a talc-like residual feel later on.
Additionally, RHEOCARE HSP 1180 will act as an auxiliary-thickening agent particularly in hydro alcoholic systems which are resistant to viscosity build-up.

Furthermore, because RHEOCARE HSP 1180 contains, as part of its molecular structure, sulfonic acid groups, it is soluble in strong acids and strong bases (where it can be effectively neutralized by a host of alkaline cations).
RHEOCARE HSP 1180 is ideally suited for application in creams and lotions, liquid (i.e. rollons) antiperspirants, shaving creams, nail polish removers, liquid and bar soaps, after-bath splashes, and other areas where lubricious effects and/or viscosity effects are desired

FEATURES OF RHEOCARE HSP 1180:
RHEOCARE HSP 1180 is Anionic polymer with high slip/ lubricity for wide range of cosmetic applications, especially hair care
RHEOCARE HSP 1180 is Cold processable
RHEOCARE HSP 1180 Does not contain preservatives
RHEOCARE HSP 1180 is Suitable for EO-free solutions


APPLICATIONS OF RHEOCARE HSP 1180:
• After Sun
• Antiperspirants & Deodorants
• Body Care
• Color Care
• Conditioning
• Face Care Face Cleansing
• Personal Care Wipes
• Self Tanning
• Sun Protection


SAFETY INFORMATION ABOUT RHEOCARE HSP 1180:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product




CHEMICAL AND PHYSICAL PROPERTIES OF RHEOCARE HSP 1180:
Appearance Conforms to standard
Acid Value (MG KOH/G), IN H2O 37.00 - 48.00
pH, 1% Solution 1.00 - 3.00
Solids, % 14.00 - 18.00
Viscosity, CPS, 25C, RVT#7, 2.5RPM 200000 - 600000.
Trade name:
Rheocare® HSP-1180
Inci :
Polyacrylamidomethlpropane Sulfonic Acid
Application :
Thickener
Appearance :
Clear, slightly yellow viscous liquid
Origin BASF Germany
Packing 25kg/bag
Supplier: BASF
Details:
- RHEOCARE HSP 1180 is a homopolymer that has been designed to provide high degree of lubricity for elegant, aesthetically pleasing slip during application and plush after-feel.
RHEOCARE HSP 1180 can act as an auxiliary- thickening agent particularly in hydro-alcoholic systems which are resistant to viscosity build-up.

- RHEOCARE HSP 1180is ideally suited for application in:
* Creams and lotions
* Liquid (i.e. roll-ons) antiperspirants,
* Shaving creams, nail polish removers
* Shampoos, facial washes,
* Liquid and bar soaps, after-bath splashes, and other areas where lubricious effects and/or viscosity effects are desired.

RHEOCARE HSP 1180can also be used in hair styling products to increase the application time and ensure a smooth distribution from root to tip.
RHEOCARE HSP 1180is applicable at a broad pH range (pH 2-12).




RHEOLON CMC
RHEOLON CMC belongs to the class of anionic linear structured cellulose.
RHEOLON CMC's components consist of polysaccharide composed of fibrous tissues of plants.
RHEOLON CMC is a water soluble polymer which can be used as a polyelectrolyte cellulose derivative.

CAS: 9004-32-4
MF: C6H7O2(OH)2CH2COONa
MW: 0
EINECS: 618-378-6

Synonyms
9004-32-4, sodium;2,3,4,5,6-pentahydroxyhexanal;acetate, Carboxymethylcellulose sodium (USP), Carboxymethylcellulose cellulose carboxymethyl ether, Celluvisc (TN), Carmellose sodium (JP17), CHEMBL242021, SCHEMBL25311455, C.M.C. (TN), CHEBI:31357, Sodium carboxymethyl cellulose (MW 250000), D01544, M.W. 700000(DS=0.9), 2500 - 4500mPa.s

RHEOLON CMC are organic depressants commonly used in physico-chemical mineral flotation processes where non-valuable (gangue) minerals are separated from valuable minerals.
Functioning as a depressant reagent, during the process, RHEOLON CMC depress the unwanted mineral particles by adsorbing on them, making them hydrophilic, consequently non-floatable, whereas valuable minerals are adsorbed by reagents called collectors, making them hydrophobic, consequently floatable to the surface by air bubbles.
RHEOLON CMC can be used as an organic binder in Iron Ore Pelletization, being a substitute to what is traditionally used, Bentonite.

RHEOLON CMC(9004-32-4) is a water-soluble polymer.
As a solution in water, RHEOLON CMC has thixotropic properties.
RHEOLON CMC is useful in helping to hold the components of pyrotechnic compositions in aqucous suspension (e.g., in the making of black match).
RHEOLON CMC is also an especially effective binder that can be used in small amounts in compositions, where the binder can intcrfere with the intended effect (e.g., in strobe compositions).

However, RHEOLON CMC sodium content obviously precludes its use in most color compositions.
RHEOLON CMC is manufactured from cellulose by various proccsses that replacc some of the hy drogen atoms in the hydroxyl[OH] groups of the cellulose molecule with acidic carboxymethyl [-CH2CO.OH] groups,which are neutralized to form the corresponding sodium salt.
RHEOLON CMC is white when pure; industrial grade material may be grayish-white or cream granules or powder.

RHEOLON CMC Chemical Properties
Melting point: 274 °C (dec.)
Density: 1,6 g/cm3
FEMA: 2239
Storage temp: room temp
Solubility: H2O: 20 mg/mL, soluble
Form: low viscosity
Pka: 4.30(at 25℃)
Color: White to light yellow
Odor: Odorless
PH Range: 6.5 - 8.5
PH: pH (10g/l, 25℃) 6.0~8.0
Water Solubility: soluble
Merck: 14,1829
Stability: Stable. Incompatible with strong oxidizing agents.
EPA Substance Registry System: RHEOLON CMC (9004-32-4)

Detergent uses
Detergent Grade RHEOLON CMC is a cornerstone ingredient in modern cleaning products.
RHEOLON CMC is used for its thickening and stabilizing properties, enhancing the texture and efficiency of detergents.
RHEOLON CMC plays an important role in improving soil suspension and preventing redeposition, making it essential for high-performance laundry and dishwashing detergents.
With a tailored viscosity range, RHEOLON CMC ensures detergents maintain optimal consistency, crucial for both liquid and powder formulas.
RHEOLON CMCs compatibility with diverse detergent ingredients, including surfactants and builders, allows for versatile applications.

Laundry Detergents: Incorporate 5% RHEOLON CMC to improve soil suspension and fabric care.
Blend with surfactants, builders, and fragrance.
This formulation ensures efficient cleaning and fabric protection, making laundry detergents more effective.

Dishwashing Liquids: Use 3% RHEOLON CMC for enhanced grease removal and suds stability.
Combine with cleaning agents and scents.
This mix results in a powerful dishwashing liquid that cuts through grease and leaves dishes spotless.

Powdered Detergents: Add 4% CRHEOLON CMC to prevent caking and ensure smooth texture.
Mix with cleaning agents, brighteners, and fragrance.
This formulation keeps powdered detergents free-flowing and effective.

Hand Washes: Blend 2% RHEOLON CMC for a luxurious, moisturizing feel.
Include cleansing agents and essential oils.
This composition creates hand washes that clean effectively while being gentle on the skin.

Surface Cleaners: Incorporate 1.5% RHEOLON CMC to enhance cleaning power and leave a streak-free finish.
Mix with disinfectants and fragrances.
This formula is ideal for multi-surface cleaners that effectively clean and freshen surfaces.

Car Wash Solutions: Use 2% RHEOLON CMC to remove tough dirt and grime.
Combine with cleaning agents and wax for shine.
This formulation results in a car wash solution that cleans effectively without damaging the vehicle’s finish.

Fabric Softeners: Add 3% RHEOLON CMC to fabric softeners for improved texture and fabric conditioning.
Blend with softening agents and scents. This formula makes fabrics feel soft and smell fresh.

Toilet Bowl Cleaners: Incorporate 2% RHEOLON CMC for enhanced cling to bowl surfaces.
Mix with disinfectants and cleaning agents. This formula ensures a thorough clean and lasting freshness in toilet bowl cleaners.

Textile uses
Textile Grade RHEOLON CMC is an essential component in the textile industry, widely used for its diverse applications.
Primarily, RHEOLON CMC’s employed as a thickening agent in textile printing, constituting about 2-3% of printing pastes, to achieve sharp, clear designs.
In dyeing processes, RHEOLON CMC, at a concentration of 1-2%, aids in uniform dye dispersion and fixation, ensuring vibrant and consistent colors.
RHEOLON CMC’s also used in fabric finishing, at about 0.5-1%, to enhance fabric hand feel and texture.
Additionally, RHEOLON CMC serves as a binding agent in non-woven fabrics, contributing to the strength and stability of the material.
In sizing applications, about 1-3% of RHEOLON CMC is used to protect yarns during weaving, reducing breakages.
RHEOLON CMC’s role in fabric softening and conditioning is pivotal, improving the overall quality and wearability of textiles.

Textile Printing: Mix 3% RHEOLON CMC to create thickened printing pastes, ensuring precise and vibrant prints on fabrics. Blend with dyes and water to achieve desired consistency.
This application results in sharp, clear textile designs that are visually appealing.

Fabric Dyeing: Use 2% RHEOLON CMC for even dye distribution and improved color fixation in fabric dyeing.
Combine with fabric dyes and water, ensuring uniform application.
This leads to consistently colored fabrics with long-lasting hues.

Fabric Finishing: Incorporate 1% RHEOLON CMC in finishing solutions to enhance fabric feel and appearance.
Mix with finishing agents and apply to textiles.
This application gives fabrics a soft, luxurious texture and improves wear resistance.

Yarn Sizing: Apply 3% RHEOLON CMC in sizing mixtures to protect yarn during weaving.
Blend with starches and size mixtures, enhancing yarn strength and reducing breakages in the loom.
This ensures smoother weaving and higher-quality textiles.

Non-Woven Fabric Production: Use 2% RHEOLON CMC as a binder in non-woven fabrics for increased strength and stability.
Combine with fibrous materials, creating durable and cohesive non-woven textiles used in various applications.

Fabric Softening: Add 1.5% RHEOLON CMC to softening solutions for a softer fabric hand feel.
Mix with softeners and apply to textiles, resulting in comfortable and pleasant-to-touch fabrics, ideal for clothing and home textiles.

Textile Coatings: Incorporate 2.5% RHEOLON CMC in coating formulations to improve fabric coating uniformity.
Blend with coating materials, enhancing the protective properties of coated fabrics used in specialty applications.

Printing Thickener Replacement: Use RHEOLON CMC as an eco-friendly alternative to synthetic thickeners in printing pastes.
Mix 3% RHEOLON CMC to achieve the desired viscosity, providing a sustainable and effective solution for textile printing.

Synthesis
RHEOLON CMC is formed when cellulose reacts with mono chloroacetic acid or its sodium salt under alkaline condition with presence of organic solvent, hydroxyl groups substituted by Sodium carboxymethyl groups in C2, C3 and C6 of glucose, which substitution slightly prevails at C2 position.
Generally, there are two steps in manufacturing process of sodium carboxymethyl cellulose, alkalinization and etherification.
Step 1: Alkalinization
Disperse the raw material cellulose pulp in alkali solution (generally sodium hydroxide, 5–50%) to obtain alkali cellulose.
Cell-OH+NaOH →Cell·O-Na+ +H2O
Step 2: Etherification
Etherification of alkali cellulose with sodium monochloroacetate (up to 30%) in an alcohol-water medium.
The mixture of alkali cellulose and reagent is heated (50–75°C) and stirred during the process.
ClCH2COOH+NaOH→ClCH2COONa+H2O
Cell·O-Na+ +ClCH2COO- →Cell-OCH2COO-Na
The DS of the sodium RHEOLON CMC can be controlled by the reaction conditions and use of organic solvents (such as isopropanol).
RHEOSOLVE T 633
Rheosolve T 633 is milky white liquid, but creates transparent formulations.
Rheosolve T 633 is a white, and opaque flowing dispersion.


CAS Number: 999999-89-7
INCI: Acrylates/Beheneth-25 Methacrylate


Rheosolve T 633 is an acrylic thickener in aqueous dispersion specifically designed for the household, industrial and institutional detergent industry.
Rheosolve T 633 is easy to use and provides instantaneous thickening effect.
Rheosolve T 633 do not freeze , properties are irreversible after freezing.


Rheosolve T 633 must be protected from the elements and stored at temperatures between 5 and 40 °C and protected from direct sunlight.
Rheosolve T 633 is an acrylic thickener which produces low viscosity formulations with excellent suspending properties.
Rheosolve T 633 is suitable for high pH applications and is compatible with 30% NaOH (eg. for Oven cleaners).


Rheosolve T 633’s high yield stress and pseudoplastic properties, mean that it is ideal for application onto vertical surfaces where it shows little sagging.
Rheosolve T 633 is milky white liquid, but creates transparent formulations.


Rheosolve T 633 is an acrylic thickener which produces low viscosity formulations with excellent suspending properties.
Rheosolve T 633 is a copolymer of the ester of methacrylic acid and Beheneth-25 and one or more monomers of acrylic acid, methacrylic acid, or one of their simple esters.


Rheosolve T 633 is a white, and opaque flowing dispersion.
Rheosolve T 633 functions as an aqueous viscosity increasing agent.
Rheosolve T 633 works as a rheology modifier or viscosity controller in cosmetics and personal care products.
Rheosolve T 633 in hair products is commonly found in clear shampoos, hair conditioners, and hair dye developers.



USES and APPLICATIONS of RHEOSOLVE T 633:
Rheosolve T 633 is used highly alkaline formulations.
Rheosolve T 633 can be used to efficiently thicken highly alkaline formulations (such as sodium or potassium hydroxide.
Rheosolve T 633 is an acrylic thickener in aqueous dispersion specifically designed for the household, industrial and institutional detergent industry.


Rheosolve T 633 is easy to use and provides instantaneous thickening effect.
Rheosolve T 633 is thickens formulations with high pH 7-14 and alcohol mixtures.
Rheosolve T 633 is an effective acrylic thickener for neutral, slightly alkaline and highly alkaline formulations.


These products have good heat stability, are compatible with sodium hypochlorite, stabilizer suspensions and can be used to produce a wide range of formulations such as bleaches, disinfectants, alcohol solutions, abrasive pastes and creams, Rheosolve T 633 is also used in products such as oven and grill cleaners , high alkaline cleaners.


Rheosolve T 633 is easy to use.
Rheosolve T 633 has instant thickening effect.
Recipes based on them have pseudo-plasticity, which Rheosolve T 633 also allows them to be effectively used for processing vertical surfaces.


Rheosolve T 633 is used to stabilize highly concentrated suspensions such as calcium carbonate and eco-labeled products.
Rheosolve T 633 is an acrylic thickener in aqueous dispersion for the household, industrial and institutional detergent industry.
Rheosolve T 633 is specifically designed to thicken high pH formulations.


Rheosolve T 633 is easy to use and provides instantaneous thickening effect.
Rheosolve T 633 is an acrylic thickener in aqueous dispersion for the household, industrial and institutional detergent industry.
Rheosolve T 633 is specifically designed to thicken high pH formulations.


Rheosolve T 633 is easy to use and provides instantaneous thickening effect.
Rheosolve T 633 is used in abrasives pastes, scrubbing creams, all-purpose cleaners (hard surfaces, oven, grill cleaners, acid formulations) and for the stabilization of highly concentrated suspension such as calcium carbonate.


Rheosolve T 633 is used in gels, input from 4.5%
Product performance and application of Rheosolve T 633: particle stabilizer, suitable for highly alkaline systems.
Rheosolve T 633 is suitable for high pH applications and is compatible with 30% NaOH (eg. for Oven cleaners).


Rheosolve T 633’s high yield stress and pseudoplastic properties, mean that it is ideal for application onto vertical surfaces where it shows little sagging.
Rheosolve T 633 is used in abrasives pastes, scrubbing creams, all-purpose cleaners (hard surfaces, oven, grill cleaners, acid formulations) and for the stabilization of highly concentrated suspension such as calcium carbonate.


Rheosolve T 633 in skin care is found in bath and body care products, sun care products, soaps, eye contour products, etc.
Rheosolve T 633 has been found to be used at a maximum concentration of 0.3-1.7% in leave-on products and 0.05-1% in rinse-off products.



ADVANTAGES OF RHEOSOLVE T 633:
Highly Versatile Thickener at high pH Rheosolve T 633 allows an accurate adjustment of the rheology solving then many formulation issues even in very alkaline media.
Contribute to the granting of Rheosolve T 633 is non hazardous and also exempt from REACH.



WHAT DOES RHEOSOLVE T 633 DO IN A FORMULATION?
*Viscosity controlling



SAFETY PROFILE OF RHEOSOLVE T 633:
The Cosmetic Ingredient Review (CIR) Expert Panel reviewed available scientific data supporting the safety of 126 acrylates copolymers including Rheosolve T 633 and concluded that they are safe in cosmetics and personal care products in the present practices of use and concentration when formulated to be non-irritating to skin.



ALTERNATIVES OF RHEOSOLVE T 633:
*ACRYLATES C10 30 ALKYL METHACRYLATE COPOLYMER, *ACRYLATES ETHYLHEXYL ACRYLATE COPOLYMER,
*LAURYL ACRYLATE CROSSPOLYMER



PROPERTIES OF RHEOSOLVE T 633:
For thickening alkaline formulations of household chemicals, including those containing abrasives.



STORAGE OF RHEOSOLVE T 633:
Rheosolve T 633 – do not freeze, properties are irreversible after freezing.
Rheosolve T 633 must be protected from the elements and stored at temperatures between 5 and 40 °C and protected from direct sunlight.



HANDLING & STORAGE OF RHEOSOLVE T 633:
Rheosolve T 633 can be irreversibly altered by frost.
Rheosolve T 633 should be protected from the effects of weathering and stored between 5 and 40°C and protected from direct sun exposure.
Once opened, packaging should be resealed immediately after use.

Film-forming at the surface of Rheosolve T 633 and/or sedimentation at the bottom of the packaging may happen.
These phenomenon are normal and have no impact on the level of performances as long as the product meet the specifications.
It is recommended to filter Rheosolve T 633 prior to use with a 400μm or 40 mesh filter.
In these conditions, Rheosolve T 633 should be used within 6 months from delivery.



PHYSICAL and CHEMICAL PROPERTIES of RHEOSOLVE T 633:
Nature: Acrylic copolymer in aqueous dispersion
Appearance (20°C): Low viscous white milky liquid
Solids content (%): 30
pH (20°C): 4
Specific gravity (20°C): 1.06
Nature: Acrylic copolymer
Appearance: Milky liquid
Solid Content (%): 30
pH: 4
Specific gravity: 1.06
Melting Point: >100°C
Solubility: Insoluble in water at pH 2-3; soluble in water at pH 6-8



FIRST AID MEASURES of RHEOSOLVE T 633:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of RHEOSOLVE T 633:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of RHEOSOLVE T 633:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of RHEOSOLVE T 633:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of RHEOSOLVE T 633:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of RHEOSOLVE T 633:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


RHEOVIS PU 1215



Rheovis PU 1215 is an innovative synthetic polyurethane polymer system engineered to enhance the properties of latex coatings and adhesives.
When incorporated into paint systems, Rheovis PU 1215 exhibits a unique trait of reduced shear thinning compared to traditional cellulosic thickeners.



APPLICATIONS


In maintenance coatings, Rheovis PU 1215 ensures even application, extending the lifespan of protective finishes.
Concrete coatings formulated with the polymer achieve smoother application on concrete surfaces, enhancing their visual appeal.
Rheovis PU 1215 plays a crucial role in achieving high-quality finishes in both retail and high-end paints.

Rheovis PU 1215 aids in the formulation of pool coatings, ensuring uniform application and enhancing the pool's appearance and durability.
Rheovis PU 1215 is essential in creating barrier coatings that effectively shield surfaces from moisture, chemicals, and pollutants.

Its controlled application benefits sports surface coatings, providing consistent playing conditions and aesthetics.
Rheovis PU 1215 is used in coating repair solutions, enabling precise touch-ups and maintaining the integrity of coated surfaces.
Rheovis PU 1215 contributes to the formulation of fire-retardant coatings, enhancing adherence and effectiveness in fire protection.

Artists use Rheovis PU 1215 to achieve precise brush drags and controlled flow in their paintings, enhancing their creative expression.
DIY coating kits benefit from the polymer's inclusion, allowing consumers to achieve professional-level application results at home.


Some of its key applications include:

Latex Paints:
Rheovis PU 1215 finds primary application as an additive in latex paints, where it enhances flow, leveling, and brush drags for improved coating quality.

Adhesive Formulations:
Rheovis PU 1215 is utilized to enhance the performance of adhesive formulations, enabling better application and bonding properties.

Architectural Coatings:
Rheovis PU 1215 is a valuable ingredient in architectural coatings, ensuring consistent and high-quality finishes for buildings.

Interior Wall Paints:
Rheovis PU 1215 is commonly used in interior wall paints to achieve a smooth appearance and enhanced application characteristics.

Exterior House Paints:
In exterior house paints, Rheovis PU 1215 contributes to durability and weather resistance, ensuring long-lasting protection.

Decorative Coatings:
Rheovis PU 1215 enhances the aesthetics of decorative coatings by providing excellent flow, leveling, and an even application.

Wood Coatings:
Rheovis PU 1215 is incorporated into wood coatings to improve their workability and deliver uniform coverage on various wood surfaces.

Furniture Finishes:
Rheovis PU 1215 plays a role in furniture finishes, offering improved flow for a more polished and professional look.

Automotive Coatings:
Rheovis PU 1215 can be found in automotive coatings, contributing to a smooth finish and enhancing the overall appearance of vehicles.

Industrial Coatings:
Rheovis PU 1215 is used in industrial coatings to optimize application properties, ensuring consistent results in demanding environments.

Maintenance Coatings:
Maintenance coatings benefit from Rheovis PU 1215's properties, achieving effective application and extended protection.

Architectural Paints:
Rheovis PU 1215 is an essential component in architectural paints, allowing for controlled application and a uniform finish on various surfaces.

Metal Coatings:
Rheovis PU 1215 is employed in metal coatings to improve the coating's appearance and provide enhanced resistance against environmental factors.

Roof Coatings:
Rheovis PU 1215 contributes to the formulation of roof coatings that offer excellent flow and durability, protecting buildings from the elements.

Masonry Coatings:
In masonry coatings, Rheovis PU 1215 ensures uniform application and improved adhesion to diverse substrates.

Floor Coatings:
Rheovis PU 1215 enhances the performance of floor coatings, offering better leveling and surface coverage for durable and visually appealing results.

Specialty Coatings:
Specialty coatings, such as those used in artistic and creative applications, benefit from Rheovis PU 1215's unique flow and control properties.

Textured Coatings:
Textured coatings gain improved application characteristics, resulting in more controlled texture creation and a consistent finish.

Retail Paints:
Rheovis PU 1215 contributes to retail paints' attractiveness by ensuring smoother application, even for DIY consumers.

Environmental Coatings:
Rheovis PU 1215 is utilized in environmental coatings designed to withstand harsh outdoor conditions and provide lasting protection.

High-End Finishes:
Rheovis PU 1215 is an asset in achieving high-end finishes, offering superior brush drags and excellent flow for meticulous results.

Facade Coatings:
Rheovis PU 1215 enhances the performance of facade coatings, which need to withstand weathering and pollution while maintaining a clean appearance.

Protective Coatings:
In protective coatings, Rheovis PU 1215 ensures even application, improving the coating's ability to shield surfaces from damage.

Roofing Sealants:
Rheovis PU 1215 is incorporated into roofing sealants to enhance their application and ensure effective sealing against moisture and the elements.

Coating Repair Solutions:
Rheovis PU 1215 aids in coating repair solutions, allowing for precise and uniform touch-ups to maintain the integrity of coated surfaces.

Elastomeric Coatings:
In elastomeric coatings, Rheovis PU 1215 contributes to flexible and durable finishes, adapting to substrate movements without compromising appearance.

Concrete Coatings:
Rheovis PU 1215 is utilized in concrete coatings to achieve smoother and more controlled application on concrete surfaces, enhancing their visual appeal.

Stain Blockers:
Rheovis PU 1215 is integrated into stain-blocking coatings, ensuring uniform coverage and effective resistance against various stains.

Stucco Coatings:
In stucco coatings, Rheovis PU 1215 improves the coating's ability to adhere to textured surfaces, delivering consistent coverage.

Graffiti-Resistant Coatings:
Rheovis PU 1215 enhances the formulation of graffiti-resistant coatings, providing both functional protection and aesthetic appeal.

Undercoats and Primers:
Rheovis PU 1215 is incorporated into undercoats and primers to improve their leveling and adhesion properties, enhancing topcoat application.

Barrier Coatings:
Barrier coatings benefit from Rheovis PU 1215's even application, creating an effective barrier against moisture, chemicals, and pollutants.

Roof Waterproofing:
Rheovis PU 1215 aids in roof waterproofing coatings by improving the coating's ability to adhere to the surface and provide lasting waterproofing protection.

Anti-Corrosion Coatings:
Rheovis PU 1215 enhances anti-corrosion coatings, contributing to an even application that prevents rust and deterioration.

Agricultural Coatings:
Rheovis PU 1215 is utilized in agricultural coatings for equipment and structures, ensuring proper coverage and protection against outdoor conditions.

Playground Surface Coatings:
In coatings for playground surfaces, Rheovis PU 1215 provides consistent coverage and protection for safe and durable play areas.

Sports Surface Coatings:
Sports surface coatings benefit from Rheovis PU 1215's controlled application, maintaining consistent playing conditions and aesthetics.

Traffic Paints:
Rheovis PU 1215 is used in traffic paints to ensure uniform application on roadways, contributing to clear and durable road markings.

Marine Coatings:
Rheovis PU 1215 enhances marine coatings' ability to adhere to various surfaces, protecting them from water exposure and environmental factors.

Pool Coatings:
In pool coatings, it aids in achieving smooth and even finishes, enhancing the pool's appearance and durability.

Faux Finishes:
Rheovis PU 1215 plays a role in faux finishes, enabling controlled application techniques to create intricate patterns and designs.

Metallic Coatings:
Rheovis PU 1215 contributes to consistent application in metallic coatings, ensuring even distribution of metallic pigments for a striking finish.

Electrostatic Coatings:
In electrostatic coatings, it enhances even deposition of the coating material, improving adhesion and surface coverage.

Reflective Coatings:
Reflective coatings benefit from Rheovis PU 1215's ability to maintain consistent thickness, ensuring uniform reflectivity and appearance.

HVAC Coatings:
Rheovis PU 1215 is used in coatings for HVAC systems to ensure uniform application on complex surfaces, enhancing durability and corrosion resistance.

Soundproofing Coatings:
Rheovis PU 1215 contributes to the formulation of soundproofing coatings, providing smooth coverage on surfaces while reducing noise transmission.

Fire-Retardant Coatings:
In fire-retardant coatings, it enhances the coating's adherence to surfaces, improving its effectiveness in fire protection.



DESCRIPTION


Rheovis PU 1215 is an innovative synthetic polyurethane polymer system engineered to enhance the properties of latex coatings and adhesives.
When incorporated into paint systems, Rheovis PU 1215 exhibits a unique trait of reduced shear thinning compared to traditional cellulosic thickeners.
Its less elastic behavior enhances the application experience, enabling controlled paint application through brushes and rollers.
Paints enriched with Rheovis PU 1215 offer superior brush drags, enabling smoother and more effective applied film build during coating.


Rheovis PU 1215 has several important features:

Aesthetic Enhancement:
Rheovis PU 1215 contributes to excellent flow and leveling, resulting in a refined appearance and uniform surface texture.

Spatter Control:
Users can expect minimal roller spatter during application, ensuring a cleaner and more efficient painting process.

Durability and Maintenance:
With its good scrub resistance, paints containing Rheovis PU 1215 can withstand cleaning and maintenance without compromising quality.

High-Performance Formulation:
Recommended for high-volume solids paints, Rheovis PU 1215 is particularly suitable for applications where performance quality is paramount.

Interior and Exterior Applications:
Its attributes shine in both interior and exterior trade sales coatings, offering essential benefits for brush and roller application properties.

Collaborative Thickening:
Rheovis PU 1215 works optimally when formulated alongside auxiliary thickeners like attapulgite clays, low molecular weight cellulosics, or biogums.

Customizable Viscosity:
While Rheovis PU 1215 can be directly added to paint, Rheovis PU 1215's viscosity can be tailored for easier handling through dilution with water-soluble coalescents.



PROPERTIES


Physical Properties:

Appearance: Opaque white liquid
Viscosity: 3,000 cps
Activity (%):
By weight: 20.0%
By volume: 17.9%
pH (2% aqueous solution): 7.0
Density:
lb/gal: 8.65
g/ml: 1.035


Product Range:

Viscosity (cps): 1,500 – 4,000 (N-114)
Solids (%): 28.5 – 31.5 (JC-111)
Specific Gravity: 1.020 – 1.050 (N-226)
pH (2% in water): 6.5 – 7.5 (N-117)



FIRST AID


First Aid Measures:

Inhalation:

If inhaled, move the person to fresh air immediately.
If breathing is difficult, provide oxygen if available and seek medical attention.


Skin Contact:

Remove contaminated clothing and shoes.
Wash the affected skin area thoroughly with soap and water.
If irritation persists, seek medical attention.


Eye Contact:

Rinse the eyes gently with water for at least 15 minutes, while keeping the eyelids open.
Remove contact lenses if present and easy to do so.
Seek medical attention if irritation or redness persists.


Ingestion:

Do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek medical attention immediately, and provide the doctor with information about the product.


Notes to Physicians:

Treat symptomatically and supportively.
In case of inhalation of significant amounts of fumes or vapors, provide appropriate supportive care.

RHEOVIS PU 1256
Rheovis PU 1256



APPLICATIONS


Rheovis PU 1256 is used in aqueous paint formulations allows to achieve these advantages:

Improved flow
Improved gloss
Increased hiding power
Reduced splattering when paint is applied by roller
Increased resistance to washing and scrubbing
Long open time


Rheovis PU 1256 is film-forming.
Furthermore, Rheovis PU 1256 has a good pigment-binding capacity.

Rheovis PU 1256 is outstandingly resistant to UV radiation.
Moreover, Rheovis PU 1256 is an associative polyurethane thickener.

Rheovis PU 1256 İS designed to modify the rheology in aqueous polymer emulsions.
Besides, Rheovis PU 1256 is more effective in anionic emulsion types and pure acrylics.
Rheovis PU 1256 is also effective in styrene-acrylic systems than in protective colloid emulsions such as VeoVa 1.


Rheovis PU 1256 is recommended for use in:

House paints
Synthetic plasters
Emulsion paints
Adhesives
Fillers
Anti-corrosive paints


Rheovis PU 1256 can be formulated with other thickeners such as cellulose derivatives and acrylate thickener.

The recommended dosage of Rheovis PU 1256 is 1 – 3% on total formulation.
However, this depends on pigmentation, dispersion type, amount of binder and co-solvents used.

Rheovis PU 1256 may be added at any stage of paint manufacture.
However, it is recommended to incorporate Rheovis PU 1256 while stirring – without any dilution – directly to the pigment paste before the grinding stage.

Rheovis PU 1256 can also be added at the final stage of the paint manufacture.
In addition, Rheovis PU 1256 should then be prediluted 1:1 – 1:5 in propylene glycol or butyl glycol to achieve perfect incorporation into the system.

Rheovis PU 1256 is recommended for use in house paints, synthetic plasters, emulsion paints, adhesives, fillers and anti-corrosive paints. Additionally, Rheovis PU 1256 can be formulated with other thickeners such as cellulose derivatives and acrylate thickener.


Applications of Rheovis PU 1256:


ACE
Automotive coatings
Architectural coatings
Building materials
Construction coatings
Elastomeric roof coatings
Furniture and wood coatings
Industrial coatings
Marine coatings
Nonwovens
Overprint varnish (OPV)
Printing and packaging


Key features & benefits of Rheovis PU 1256:

Broad range of rheology profiles
Highly efficient across many resin types
Improved wash and scrub resistance
Excellent leveling
Reduced spattering
Not susceptible to microbial attack


Rheovis PU 1256 is a mid-shear thickener.
More to that, Rheovis PU 1256 is slightly pseudoplastic.


Advantages of Rheovis PU 1256:

Imparts no negative effects in gloss.
Offers improved flow and increment of hiding power.
Exhibits splashing reduction during roller application.
Provides increment of wash and scrub resistance and pH-independent properties.
Shows very good film forming properties, good pigment wetting and a high UV stability.


Other Applications of Rheovis PU 1256:

Front coatings
Synthetic plasters
Emulsion paints
Fillers and anti-corrosive paints
Marine /Anti-Corrosive / Protective



DESCRIPTION


Rheovis PU 1256 is an associative polyurethane thickener.
Further to that, Rheovis PU 1256 gives aqueous systems a pseudoplastic behavior.
The properties of Rheovis PU 1256 are independent of the pH.

The chemical nature of Rheovis PU 1256 is solution of a polyurethane in water/liquefier.
Rheovis PU 1256 (formerly DSX 3256) is a non-ionic mid-shear solvent-free rheology additive for aqueous coatings.
Furthermore, Rheovis PU 1256 is an associative polyurethane thickener that gives aqueous systems a pseudoplastic behavior.

The properties of Rheovis PU 1256 are independent of the pH.
Rheovis PU 1256 is more effective in anionic emulsion types, pure acrylics and styrene-acrylic systems than in protective colloid emulsions such as VeoVa™ 1.

Rheovis PU 1256 (Old Name: DSX 3256) is an associative polyurethane thickener that gives aqueous systems a pseudoplastic behavior.
Moreover, Rheovis PU 1256 is a non-ionic mid-shear solvent-free rheology additive for aqueous coatings.
Rheovis PU 1256 exhibits improved flow, gloss, increased hiding power and long open time.

Besides, Rheovis PU 1256 provides reduced splattering when paint is applied by roller.
Rheovis PU 1256 offers increased resistance to washing and scrubbing.

In addition, Rheovis PU 1256 is film-forming, has a good pigment-binding capacity and is outstandingly resistant to UV radiation.
Rheovis PU 1256 is recommended for house paints, emulsion paints and anti-corrosive paints.

Rheovis PU 1256 has a shelf life of 1 year.
Recommended dosage of Rheovis PU 1256 is 1-3% on total formulation.

Rheovis PU 1256 is a solution of a polyurethane in water/diluent.
Additionally, Rheovis PU 1256 acts as an associative polyurethane thickener for aqueous coatings.



PROPERTIES


Physical form of Rheovis PU 1256 is viscous liquid.

Typical properties of Rheovis PU 1256:

solids content: ~ 43 %
density at 20 °C: (68 °F) ~ 1.08 g/cm3
Brookfield viscosity at 23 °C: (73 °F) ~ 20,000 mPa. s



HANDLING AND STORAGE


Shelf life OF Rheovis PU 1256:

When stored under the usual appropriate storage conditions, Rheovis PU 1256 can be stored for 1 year.



SYNONYMS


DSX 3256
Rhodamine B
RIBOFLAVIN TETRABUTYRATE N° CAS : 752-56-7 Nom INCI : RIBOFLAVIN TETRABUTYRATE Nom chimique : Riboflavin, 2',3',4',5'-tetrabutanoate N° EINECS/ELINCS : 212-034-5 Ses fonctions (INCI) Agent d'entretien de la peau : Maintient la peau en bon état
RHODAPON LS 94RPB
Rhodapon LS 94RPB is a high-purity Sodium Lauryl Sulphate (SLS), offering a white to creamish powder appearance at 25°C, making it suitable for a range of applications, particularly in dental products where it serves as an efficient foaming agent.
In coatings, Rhodapon LS 94RPB stands out as an APE (alkylphenol ethoxylate)-free, high-concentration (solid version) SLS utilized in emulsion polymerization for various polymer systems.
Rhodapon LS 94RPB offers several key benefits, such as improving latex stability, and it contributes to sustainability by being APE-free and enhancing polymer stability, leading to increased durability.
Additionally, Rhodapon LS 94RPB promotes resource efficiency by reducing troubles in the production process.

CAS Number: 68585-47-7
EC Number: 271-557-7



APPLICATIONS


Rhodapon LS 94RPB is widely employed in dental products, serving as a foaming agent in toothpaste formulations.
Rhodapon LS 94RPB's high purity and efficiency make it an ideal choice for enhancing the foaming properties in dental care products.

In hair care formulations, Rhodapon LS 94RPB contributes to the luxurious lathering effect in shampoos, providing a pleasant user experience.
Foam baths benefit from the inclusion of Rhodapon LS 94RPB, creating rich and stable foam for an indulgent bathing experience.

Shower products, including shower gels and body washes, utilize Rhodapon LS 94RPB to enhance foam consistency and quality.
Liquid soaps leverage the surfactant's properties to achieve effective cleansing with a desirable foaming texture.
Creams and lotions in the cosmetic industry incorporate Rhodapon LS 94RPB to improve texture and provide a smooth application.

Rhodapon LS 94RPB finds application in toilet bars, contributing to the foaming and cleansing properties of solid soap formulations.
Rhodapon LS 94RPB is a versatile ingredient in personal care products, catering to a range of formulations for diverse consumer needs.
Its APE-free composition aligns with sustainable practices, making it a responsible choice for environmentally conscious formulations.

In the coatings industry, Rhodapon LS 94RPB is utilized as an APE-free high-concentration solid version SLS in emulsion polymerization.
Rhodapon LS 94RPB plays a crucial role in improving latex stability, contributing to the overall quality of polymer systems.
Its use in emulsion polymerization enhances the durability and performance of coatings, ensuring long-lasting and resilient finishes.
Rhodapon LS 94RPB's resource efficiency reduces production challenges, streamlining manufacturing processes in the coatings sector.

Rhodapon LS 94RPB's anionic ionic character makes it well-suited for various applications, ensuring compatibility with different systems.
Beyond its role in coatings and personal care, Rhodapon LS 94RPB finds utility in diverse formulations across industries.

Its presence in dental and personal care products underscores its importance in delivering desired sensory and performance attributes.
Rhodapon LS 94RPB contributes to the overall aesthetic appeal of formulations, enhancing the user experience in various products.
Rhodapon LS 94RPB's effectiveness in creating stable foam makes it an essential ingredient in a broad spectrum of consumer goods.

Rhodapon LS 94RPB's applications extend to different polymer systems, showcasing its versatility and adaptability in various industries.
Sustainable features, such as being APE-free, make Rhodapon LS 94RPB a preferred choice for manufacturers aiming for eco-friendly formulations.

Its compatibility with different materials and formulations underscores its role as a versatile and adaptable surfactant.
Rhodapon LS 94RPB's standardized specifications and high purity make it a reliable component in formulations across the personal care and coatings sectors.
Rhodapon LS 94RPB's contribution to resource efficiency and stability aligns with modern industry demands for sustainable and effective ingredients.
From toothpaste to coatings, Rhodapon LS 94RPB demonstrates its efficacy and versatility, making it a valuable component in diverse formulations.

RHODAPON LS 94RPB is a high purity Sodium Lauryl Sulphate, which is suitable for use in dental products as foaming agents.
Rhodapon LS 94RPB is used in following formulations:
Toothpaste
Hair shampoos
Foam baths
Shower products
Liquid soaps
Creams and lotions
Toilet bars

Rhodapon LS 94RPB finds a crucial role in toothpaste formulations, ensuring not only efficient foaming but also providing a consistent texture during brushing.
Its high active content of 94% minimum makes Rhodapon LS 94RPB an impactful ingredient in dental care products, where precise formulations are essential.
Hair shampoos benefit from Rhodapon LS 94RPB's ability to generate rich foam, imparting a sense of luxury and effectiveness in cleansing.

Foam baths incorporating Rhodapon LS 94RPB create a luxurious bathing experience, where stable and long-lasting foam enhances the overall product appeal.
Rhodapon LS 94RPB is an integral part of shower products, contributing to their effectiveness in cleansing and ensuring a pleasing foaming sensation.
Liquid soaps formulated with Rhodapon LS 94RPB exhibit enhanced lathering properties, making them suitable for various personal and industrial applications.

In creams and lotions, Rhodapon LS 94RPB improves the overall texture, facilitating smooth application and absorption into the skin.
The inclusion of Rhodapon LS 94RPB in toilet bars ensures a pleasant foaming effect, making solid soap formulations effective and user-friendly.

Its versatility in personal care applications extends to various cosmetic formulations, adding value to diverse beauty and skincare products.
Rhodapon LS 94RPB's APE-free composition aligns with the growing demand for environmentally conscious ingredients in personal care formulations.
Coatings benefit from Rhodapon LS 94RPB as an APE-free high-concentration solid version SLS in emulsion polymerization, improving stability and durability.

Rhodapon LS 94RPB's contribution to latex stability in emulsion polymerization enhances the quality and performance of coatings, ensuring lasting results.
Rhodapon LS 94RPB's role in coatings goes beyond aesthetics, impacting the fundamental properties that contribute to the durability of painted surfaces.
Its application in emulsion polymerization supports resource efficiency, reducing challenges in the production processes of coatings.

The anionic ionic character of Rhodapon LS 94RPB ensures compatibility with various polymers, contributing to its versatility in coatings.
Rhodapon LS 94RPB's adaptability makes it suitable for different polymer systems, showcasing its efficacy in various coating applications.
Rhodapon LS 94RPB's presence in dental and personal care formulations highlights its versatility, ensuring a seamless fit across a range of consumer products.

Beyond functionality, Rhodapon LS 94RPB contributes to the sensory experience of formulations, enhancing the overall feel and appeal of products.
Stable foam generation is a hallmark of Rhodapon LS 94RPB, making it a sought-after ingredient for its contribution to the aesthetic qualities of formulations.

Its applications extend beyond traditional personal care and coatings, finding utility in diverse formulations where effective foaming is desired.
The sustainability features of Rhodapon LS 94RPB make it a preferred choice for manufacturers aiming to create environmentally friendly formulations.
Compatibility with different materials and formulations underscores the surfactant's adaptability, allowing it to cater to evolving industry needs.

Rhodapon LS 94RPB's standardized specifications ensure consistent quality in formulations, meeting the stringent requirements of various industries.
In coatings, Rhodapon LS 94RPB showcases its efficacy not just in enhancing appearance but also in ensuring the longevity and performance of painted surfaces.
Rhodapon LS 94RPB stands out as a versatile and reliable component in formulations, contributing to the success of products across diverse industries.



DESCRIPTION


Rhodapon LS 94RPB is a high-purity Sodium Lauryl Sulphate (SLS), offering a white to creamish powder appearance at 25°C, making it suitable for a range of applications, particularly in dental products where it serves as an efficient foaming agent.
In coatings, Rhodapon LS 94RPB stands out as an APE (alkylphenol ethoxylate)-free, high-concentration (solid version) SLS utilized in emulsion polymerization for various polymer systems.
Rhodapon LS 94RPB offers several key benefits, such as improving latex stability, and it contributes to sustainability by being APE-free and enhancing polymer stability, leading to increased durability.
Additionally, Rhodapon LS 94RPB promotes resource efficiency by reducing troubles in the production process.

Standard applications of Rhodapon LS 94RPB encompass its use in dental products as a foaming agent, finding application in toothpaste, hair shampoos, foam baths, shower products, liquid soaps, creams and lotions, as well as toilet bars.
Rhodapon LS 94RPB is conveniently packaged in 25 Kg net polyethylene-lined HDPE laminated bags, with alternative packing sizes available upon request.
With a shelf life of 365 days, Rhodapon LS 94RPB is designed to maintain its quality and efficacy over an extended period.

Rhodapon LS 94RPB is a high-purity Sodium Lauryl Sulphate, appearing as a white to creamish powder at 25°C.
Rhodapon LS 94RPB is specifically designed for use in dental products, serving as an efficient foaming agent to enhance product performance.
With an active content of 94% minimum, Rhodapon LS 94RPB showcases a high level of purity and effectiveness in various formulations.

Its unsulphated matter is limited to 1.5%, ensuring a clean and well-defined chemical composition.
The pH of Rhodapon LS 94RPB ranges from 8.5 to 10.5 in a 1% aqueous solution, providing versatility in applications.
With a sodium chloride content not exceeding 0.5%, it meets stringent quality standards for certain applications.

The sodium sulfate content is kept at a maximum of 3.0%, contributing to the stability of the product.
Rhodapon LS 94RPB exhibits a bulk density ranging from 0.16 to 0.22 g/cm³ at 25°C, indicating its physical characteristics.

Possessing an anionic ionic character, this surfactant is well-suited for various applications in different industries.
The mean molecular weight of Rhodapon LS 94RPB is 298, indicating its molecular size and structure.
Rhodapon LS 94RPB is APE (alkylphenol ethoxylate)-free, aligning with sustainable practices and environmental considerations.

In the realm of coatings, Rhodapon LS 94RPB stands out as a high-concentration solid version SLS used in emulsion polymerization.
Its key benefits include the improvement of latex stability, contributing to the overall quality of polymer systems.

Sustainability features, such as being APE-free, make Rhodapon LS 94RPB a responsible choice for environmentally conscious applications.
Rhodapon LS 94RPB enhances polymer stability, resulting in improved durability and performance in various formulations.
Resource efficiency is achieved as Rhodapon LS 94RPB reduces troubles in production processes, optimizing manufacturing practices.
Standard applications include its use in dental products, acting as a foaming agent in toothpaste formulations.

Beyond dental care, Rhodapon LS 94RPB finds its place in hair shampoos, foam baths, shower products, and liquid soaps.
Its versatility extends to the cosmetic industry, where it is utilized in the formulation of creams, lotions, and toilet bars.
Rhodapon LS 94RPB is conveniently packaged in 25 Kg net polyethylene-lined HDPE laminated bags, ensuring ease of handling.

Alternative packing sizes are available upon request, offering flexibility based on specific production needs.
With a shelf life of 365 days, Rhodapon LS 94RPB maintains its quality and efficacy over an extended period, ensuring reliability.
Rhodapon LS 94RPB showcases a commitment to quality with specifications like active content, pH, and bulk density meeting defined standards.

Rhodapon LS 94RPB embodies a balance between performance, sustainability, and ease of use, making it a versatile choice in various applications.
As a critical component in formulations, Rhodapon LS 94RPB plays a significant role in delivering the desired properties and performance characteristics to end products.



PROPERTIES


Appearance: White to creamish powder at 25°C.
Active Content (%): 94 min.
Unsulphated Matter (%): 1.5 max.
pH (1% Aqueous Solution): 8.5 – 10.5.
Sodium Chloride (%): 0.5 max.
Sodium Sulphate (%): 3.0 max.
Bulk Density @ 25°C (g/cm³): 0.16 – 0.22.
Ionic Character: Anionic.
Mean Molecular Weight: 298.



FIRST AID


Inhalation:

If inhaled, move the person to fresh air.
If breathing is difficult, provide oxygen.
Seek medical attention if symptoms persist.


Skin Contact:

Wash affected skin with plenty of water.
Remove contaminated clothing.
If irritation occurs or persists, seek medical advice.


Eye Contact:

Rinse eyes thoroughly with water for at least 15 minutes, holding eyelids open.
Seek medical attention if irritation persists.


Ingestion:

Rinse mouth with water.
Do not induce vomiting unless directed by medical personnel.
Seek immediate medical attention.


General First Aid:

If a person is unconscious, not breathing, or experiencing severe symptoms, call emergency services immediately.
Keep a copy of the product's SDS readily available for emergency responders.



HANDLING AND STORAGE


Handling:

Personal Protection:
Use appropriate personal protective equipment (PPE), including gloves and safety goggles, when handling Rhodapon LS 94RPB.

Ventilation:
Ensure adequate ventilation in the working area to minimize inhalation exposure.
Consider the use of local exhaust systems.

Avoidance of Contact:
Avoid skin and eye contact.
In case of contact, promptly wash affected areas with water.

Avoid Ingestion:
Do not eat, drink, or smoke in areas where Rhodapon LS 94RPB is being handled.
Wash hands thoroughly after handling.


Storage:

Temperature:
Store Rhodapon LS 94RPB in a cool, dry place at temperatures recommended by the manufacturer.

Ventilation:
Provide proper ventilation in storage areas to prevent the accumulation of vapors.

Separation:
Store away from incompatible materials, such as strong acids or oxidizing agents.

Containers:
Keep the product in its original container, tightly closed when not in use.

Handling Precautions:
Follow proper handling procedures to prevent spills or leaks during storage.

Storage Segregation:
Segregate Rhodapon LS 94RPB from other chemicals based on compatibility and reactivity.

Labeling:
Ensure containers are properly labeled with product information and safety precautions.


Emergency Measures:

Emergency Procedures:
Familiarize yourself and personnel with emergency procedures, including spill response and first aid measures.

Emergency Contact:
Keep emergency contact information, including poison control and medical assistance, readily available.



SYNONYMS


C10-C16 alkyl alcohol sulfuric acid sodium salt
rhodapon LS 92 RN
rhodapon LS 94RPB
sodium tridecyl sulfate- methane(1:1:1)
sodium;methane;tridecyl sulfate
stepanol LCP
sulfuric acid mono-C10-16-alkyl esters sodium salts
sulfuric acid, mono-C10-16-alkyl esters, sodium salts
RHODAPON LS-92/RN
Rhodapon LS-92/RN is a common surfactant found in many cosmetics and personal care products.
Rhodapon LS-92/RN is the common name for ammonium dodecyl sulfate (CH3(CH2)10CH2OSO3NH4).
Rhodapon LS-92/RN is made from coconut or palm kernel oil for use primarily in shampoos and body-wash as a foaming agent.

CAS Number: 68081-96-9
EINECS Number: 268-364-5

Synonyms: Ammonium dodecyl sulfate, 2235-54-3, AMMONIUM LAURYL SULFATE, Presulin, azanium;dodecyl sulfate, Ammonium dodecyl sulphate, Sulfuric acid, monododecyl ester, ammonium salt, 68081-96-9, Q7AO2R1M0B, DTXSID2027462, Sinopon, Texapon special, Conco sulfate A, Maprofix NH, Richonol AM, Sterling AM, Neopon LAM, Akyposal als 33, Montopol LA 20, Siprol L22, Siprol 422, Texapon A 400, Lauryl ammonium sulfate, Sipon LA 30, Caswell No. 044B, Texa pon A 400, Dodecyl ammonium sulfate, Ammonium n-dodecyl sulfate, Lauryl sulfate ammonium salt, HSDB 2101, EINECS 218-793-9, UNII-Q7AO2R1M0B, EPA Pesticide Chemical Code 079028, Dodecyl sulfate ammonium salt, Sulfuric acid, lauryl ester, ammonium salt, Ammoniumdodecylsulfate, ammonium lauryl sulphate, SCHEMBL23132, 30% in H2O, C12H29NO4S, DTXCID107462, Tox21_202561, AMMONIUM LAURYL SULFATE [II], AMMONIUM LAURYL SULFATE [HSDB], AMMONIUM LAURYL SULFATE [INCI], AMMONIUM LAURYL SULFATE [VANDF], NCGC00164423-01, NCGC00260110-01, CAS-2235-54-3, DB-229811, NS00082878, D70166, A878582, Sulfuric acid, monododecyl ester, ammonium salt (1:1), ALS.

Rhodapon LS-92/RN finds extensive use in various cosmetic products, particularly in shampoos and hair care items.
Its exceptional surfactant properties allow it to effectively remove dirt, excess oil, and impurities from the hair and scalp, leaving a clean and refreshed feeling.
Moreover, Rhodapon LS-92/RN creates a rich lather, enhancing the overall shampooing experience.

Rhodapon LS-92/RN is very high-foam surfactants that disrupt the surface tension of water in part by forming micelles at the surface-air interface.
This versatile ingredient helps create luxurious lather, enhancing the cleansing and foaming properties of shampoos, body washes, and facial cleansers, providing a pleasant and refreshing experience.
The anion consists of a nonpolar hydrocarbon chain and a polar sulfate end group.

This surfactant is widely used in various personal care products, including toothpaste, hair shampoos, foam baths, shower products, liquid soaps, creams, lotions, and toilet bars.
Above the critical micelle concentration, the anions organize into a micelle, in which they form a sphere with the polar, hydrophilic heads of the sulfate portion on the outside (surface) of the sphere and the nonpolar, hydrophobic tails pointing inwards towards the center.
The water molecules around the micelle in turn arrange themselves around the polar heads, which disrupts their ability to hydrogen bond with other nearby water molecules.

The overall effect of these micelles is a reduction in surface tension of the solution, which affords a greater ability to penetrate or "wet out" various surfaces, including porous structures like cloth, fibers, and hair.
Accordingly, this structured solution allows the solution to more readily dissolve soils, greases, etc. in and on such substrates.
Rhodapon LS-92/RN however exhibit poor soil suspending capacity.

This ingredient's versatility extends beyond hair care, as it can also be found in certain skin care products, where it aids in creating cleansing and foaming properties.
Rhodapon LS-92/RN, produced by Solvay (formerly Rhodia), is a high-purity, anionic surfactant in the form of free-flowing, dust-free needles.
Rhodapon LS-92/RN is primarily composed of Sodium C12-14 Lauryl Sulfate with the CAS number 68585-47-7.

This surfactant is well-known for its excellent foaming and detergent properties, making it suitable for various personal care products such as toothpaste, hair shampoos, foam baths, shower products, liquid soaps, creams, lotions, and toilet bars.
Rhodapon LS-92/RN is typically produced by reacting lauryl alcohol with sulfur trioxide gas to form lauryl sulfate, which is then neutralized with ammonium hydroxide to create Ammonium Lauryl Sulfate.

This process results in a versatile surfactant widely used in cosmetics for its excellent cleansing and foaming properties.
Rhodapon LS-92/RN is an organic compound that belongs to the family of alkyl sulfates.
Rhodapon LS-92/RN is a clear, colorless or pale yellow liquid that is commonly used as a foaming agent and surfactant in many personal care and cleaning products.

Rhodapon LS-92/RN is derived from lauryl alcohol, which is obtained from coconut oil or palm kernel oil, and sulfuric acid.
Rhodapon LS-92/RN is commonly used in shampoos, body washes, and other personal care products to create a lathering effect and to help remove dirt, oil, and other impurities from the skin and hair.
Rhodapon LS-92/RN is a strong surfactant, which means that it is able to penetrate and break down the surface tension of oils and other substances, allowing them to be more easily washed away.

Rhodapon LS-92/RN is also a potent irritant, and can cause skin and eye irritation in some people when used in high concentrations or over prolonged periods of time.
Despite its potential for irritation, Rhodapon LS-92/RN is generally considered to be safe for use in personal care products when used according to recommended guidelines and in appropriate concentrations.
Rhodapon LS-92/RN is also biodegradable and does not accumulate in the environment, making it a more sustainable choice for cleaning and personal care applications.

Rhodapon LS-92/RN appears as white to creamish needles and has a pH range of 8.5 to 10.5 in a 1% aqueous solution.
Rhodapon LS-92/RN contains more than 92% active ingredients, with minimal impurities such as less than 0.5% sodium chloride and 3% sodium sulfate.
Its molecular weight is approximately 298 g/mol, and it has a shelf life of 12 months​.

Rhodapon LS-92/RN is a mild anionic surfactant suitable for use in formulations of neutral or slightly acidic personal care products and cosmetics such as body and hair shampoos, bubble baths and liquid soaps.
The product exhibits copious foam, outstanding detergency, wetting and emulsifying properties and easy viscosity-control.
Owing to its unique foaming properties Rhodapon LS-92/RN is also used in a number of technical applications such as fire-fighting, emulsion polymerization or oil fields.

Rhodapon LS-92/RN is an ammonium salt of ethoxylated lauryl sulfate, a surfactant that contains PEG (polyethylene glycol) in its structure.
Rhodapon LS-92/RN is classified as an alkyl sulfate and is an anionic surfactantfound primarily in shampoos and body-wash as a foaming agent.
May be contaminated with potentially toxic manufacturing impurities such as 1,4-dioxane.

Rhodapon LS-92/RN is added to products as a foaming agent, and as a detergent.
Rhodapon LS-92/RN is used in many shampoos, toothpastes, and skin cleansers.
Rhodapon LS-92/RN can cause moderate to severe skin and eye irritation.

Rhodapon LS-92/RN can also be contaminated with 1,4-Dioxane a suspected carcinogen.
The severity of the irritation to increases directly with the concentration of ALES in a product.
When combined with other chemicals, Rhodapon LS-92/RN can create nitrosamines, which are a potent class of carcinogens.

Rhodapon LS-92/RN may also damage skin’s immune system by causing skin layers to separate, inflame and age.
Rhodapon LS-92/RN is a salt classified as a sulfate ester.
Rhodapon LS-92/RN is integral to the cosmetics and personal care product industry.

Its high-foaming characteristics make it desirable in products that consumers equate with a lathering or bubbling action, such as shampoos, body washes, and bubble baths.
Its application also extends to toothpaste, facial cleansers, and shaving creams, where it aids in product distribution and enhances the overall user experience.
Rhodapon LS-92/RN can be derived from coconut and is used primarily as a detergent cleansing agent.

Rhodapon LS-92/RN is considered to be gentle and effective.
Rhodapon LS-92/RN is an anionic surfactant.
This means it lowers the surface tension of water, making the water spread more easily.

Rhodapon LS-92/RN is added to products as a foaming agent and as a detergent.
Rhodapon LS-92/RN must be used in a low-pH shampoo or shower gel since high-pH systems smell of ammonia.
Rhodapon LS-92/RN is typically used at 20-35%.

It is designed for low-pH shampoos, bath products, and cleansers requiring dense, rich foam, low color, and low odor.
Rhodapon LS-92/RN is the common name for ammonium dodecyl sulfate (CH3(CH2)10CH2OSO3NH4).
The dodecyl signifies the presence of a 12-member carbon chain in the molecular backbone which allows the molecule to bond with non-polar portions of molecules while the highly polar sulfate head allows the molecule to bond with polar molecules such as water.

Rhodapon LS-92/RN is classified as an alkyl sulfate and is an anionic surfactant found primarily in shampoos and body-wash as a foaming agent.
Rhodapon LS-92/RN is very high-foam surfactants that disrupt the surface tension of water by forming micelles around the polar water molecules.
Rhodapon LS-92/RN, an accepted contraction of sodium lauryl ether sulfate (SLES), also called sodium alkylethersulfate, is an anionic detergent and surfactant found in many personal care products (soaps, shampoos, toothpaste, etc.) and for industrial uses.

Rhodapon LS-92/RN is an inexpensive and very effective foaming agent.
Rhodapon LS-92/RN, sodium lauryl sulfate (SLS), Rhodapon LS-92/RN, and sodium pareth sulfate are surfactants that are used in many cosmetic products for their cleaning and emulsifying properties.
Rhodapon LS-92/RN is derived from palm kernel oil or coconut oil.

In herbicides, Rhodapon LS-92/RN is used as a surfactant to improve absorption of the herbicidal chemicals and reduces time the product takes to be rainfast, when enough of the herbicidal agent will be absorbed.
Its chemical formula is CH3(CH2)11(OCH2CH2)nOSO3Na.
Sometimes the number represented by n is specified in the name, for example laureth-2 sulfate.

Rhodapon LS-92/RN is heterogeneous in the number of ethoxyl groups, where n is the mean.
Rhodapon LS-92/RN is the most common one in commercial products.
Rhodapon LS-92/RN is a fantastic cleanser and foam booster that will improve the efficacy and texture of your DIY product.

Rhodapon LS-92/RN will give your formulation a rich and creamy texture, as well as thick and fluffy bubbles.
Because it is natural and organic, it is ideal for people with pH-sensitive skin.
Rhodapon LS-92/RN is a fantastic substitute for sulphate products, allowing formulation to be sulphate-free.

Rhodapon LS-92/RN is also effective with hard water.
Rhodapon LS-92/RN may be added to solid or cream goods without boiling the solution.
Rhodapon LS-92/RN is a high-purity, dust-free anionic surfactant in needle form, primarily composed of Sodium C12-14 Lauryl Sulfate (CAS: 68585-47-7).

Rhodapon LS-92/RN is known for its excellent foaming and detergent properties and is easy to disperse in water.
The combination of nonpolar and polar groups confers surfactant properties to the anion: Rhodapon LS-92/RN facilitates dissolution of both polar and non-polar materials.

Rhodapon LS-92/RN plays a crucial role in these formulations by reducing the surface tension between different substances, allowing them to mix effectively.
Rhodapon LS-92/RN is derived from lauryl alcohol, making it plant-derived in some cases.

Boiling Point: 418°C
pH: 6.5-7.5
Solubility: Soluble in water
Viscosity: Low

Rhodapon LS-92/RN, like any other surfactant, makes a good base for cleansers because of the way it disrupts the hydrogen bonding in water.
Hydrogen bonding is the primary contributor to the high surface tension of water.
In solution, the Rhodapon LS-92/RN anions and the ammonium cations separate.

Rhodapon LS-92/RN, like any other surfactant, makes a good base for cleansers because of the way it disrupts the hydrogen bonding in water.
The former align themselves into what is known as a micelle, in which the ions form a sphere, with the polar heads (the sulfate) on the surface of the sphere and the nonpolar hydrophobic tails pointing inwards towards the center.
The water molecules around the micelle arrange themselves around the polar heads, but this disrupts their hydrogen bonding with the water surrounding them.

The overall effect of having these micelles in an aqueous (water) environment is that the water becomes more able to penetrate things like cloth fibers or hair, and also becomes more readily available to solvate anything coming off the aforementioned substance.
Rhodapon LS-92/RN is prepared by ethoxylation of dodecyl alcohol, which is produced industrially from palm kernel oil or coconut oil.

The resulting ethoxylate is converted to a half ester of sulfuric acid, which is neutralized by conversion to the sodium salt.
The related surfactant Rhodapon LS-92/RN is produced similarly, but without the ethoxylation step.
Rhodapon LS-92/RN is commonly used alternatives to SLES in consumer products.

Rhodapon LS-92/RN works by removing the dirt and impurities mixed with oils in your skin and hair.
Rhodapon LS-92/RN works by allowing the mixing of these oils with water, which can now be easily rinsed away, hence cleansing the desired area.
Rhodapon LS-92/RN is recommended that it should be used at a concentration of 30% for best results.

It is soluble in water and alcohols but insoluble in volatile oils.
Rhodapon LS-92/RN is widely available across multiple regions including Asia Pacific, Europe, Latin America, and North America, and is typically used in concentrations exceeding 92% active substance.
Rhodapon LS-92/RN has minimal impurities, with sodium chloride content under 0.5% and unsulfated matter under 2%​

Hydrogen bonding is the primary contributor to the high surface tension of water.
In solution, the Rhodapon LS-92/RN anions and the ammonium cations separate.
Rhodapon LS-92/RN is another compound from a large group of surfactants playing a key role primarily in the cosmetics industry.

Rhodapon LS-92/RN (which is the INCI name of this substance) is an anionic compound that belongs to the group of alkyl sulphates.
The chemical name of this surfactant is Rhodapon LS-92/RN.
Rhodapon LS-92/RN is another surfactant found in most cosmetic products.

Due to its very good cleaning and foaming properties, as well as a milder effect on the skin and hair (vs. SLS), it is often chosen for the production of shampoos, shower gels, shaving foams and many others.
Information circulating around the Internet has raised questions about the safety of SLS (Sodium Lauryl Sulfate).
This information that is circulating also has used Rhodapon LS-92/RN as a synonym for Sodium Laureth Sulfate.

Rhodapon LS-92/RN actually stands for Sodium Lauryl Sulfate, which a different chemical.
The following information is provided from the Cosmetic Ingredient Review safety assessments of both Rhodapon LS-92/RN and SLS (Sodium Lauryl Sulfate).
Due to the fact that Rhodapon LS-92/RN is much less irritating in comparison with a popular surfactant, Sodium Lauryl Sulphate (SLS), it is a good substitute for this component, e.g. in dishwashing liquids and other household detergents.

As a washing component, Rhodapon LS-92/RN is also included in detergents dedicated to industrial applications, such as motor vehicle cleaning and maintenance.
In the construction industry, Rhodapon LS-92/RN is used in agents reducing the weight of plasterboards and in air-entraining/plasticizing admixtures.
In the chemical industry, especially in emulsion polymerization processes, it provides excellent stabilization of the polymer dispersion under lower pH ranges.

Thanks to this, it becomes possible to design the particle size, including acrylic, styrene-acrylic or VaE dispersions.
Rhodapon LS-92/RN is an indirect food additive based on lists published by the US Food and Drug Administration (FDA).

Uses:
Rhodapon LS-92/RN acts as a foaming agent that helps distribute the toothpaste more evenly while brushing and aids in cleaning the teeth effectively​​.
Rhodapon LS-92/RN is used for its ability to produce rich lather, which helps in cleaning the scalp and hair by removing oils and dirt​.
Its excellent foaming capabilities make it ideal for use in products like bubble baths and shower gels, providing a luxurious lather that enhances the user experience​.

The surfactant helps in emulsifying oils and suspending dirt particles, making it easier to wash them away with water.
In these products, Rhodapon LS-92/RN can help improve texture and consistency, allowing for easier application and better absorption by the skin.
Used in soap bars, it helps in producing a creamy lather that cleanses the skin effectively​​.

As a foaming agent, it enhances the distribution and effectiveness of the toothpaste, aiding in thorough cleaning of the teeth​.
Rhodapon LS-92/RN creates a rich lather that helps remove oils, dirt, and impurities from hair and scalp, making it a staple in hair care products​.
Its ability to produce a luxurious foam improves the sensory experience while ensuring effective cleansing​​.

In liquid hand soaps, it helps in emulsifying oils and suspending dirt, making it easier to rinse them off with water.
Rhodapon LS-92/RN improves the texture and consistency, aiding in better spreadability and absorption into the skin​.
Rhodapon LS-92/RN is used in toilet bars for its ability to produce a creamy, cleansing lather​.

Its powerful detergent properties make it effective in removing grease and grime from surfaces, hence used in various household cleaning products.
Suitable for use in heavy-duty cleaning products designed for industrial applications due to its strong emulsifying capabilities​.
Rhodapon LS-92/RN is used to stabilize emulsions, helping to mix oils and water effectively in products ranging from cosmetics to industrial cleaners.

Rhodapon LS-92/RN is used in the textile industry for processes like scouring and wetting of fabrics due to its ability to lower surface tension.
Rhodapon LS-92/RN is known for its high purity (>92% active substance), ensuring consistent performance in formulations​.
Its physical form as free-flowing, dust-free needles makes it easy to handle and incorporate into various product formulations​.

Excellent foaming properties make it a preferred ingredient in personal care and cleaning products​​.
Easily dispersible in water, which facilitates its use in aqueous formulations​.
Rhodapon LS-92/RN is an anionic surfactant which can be used in the preparation of porous building ceramics by gelcasting and formulation of cosmetic products.

Rhodapon LS-92/RN can also be used as a corrosion inhibitor for carbon steel in acidic solution.
Rhodapon LS-92/RN is commonly used in hand soaps as a foaming agent and surfactant.
Rhodapon LS-92/RN helps to create a rich lather that effectively removes dirt, oil, and other impurities from the skin.

In hand sanitizers, Rhodapon LS-92/RN is not typically used as it can be an irritant to the skin.
Instead, hand sanitizers typically contain alcohol or other antimicrobial agents that kill bacteria and viruses without the need for a foaming agent.
Rhodapon LS-92/RN’s worth noting that there are some concerns about the use of ALS in personal care products, as it can be an irritant to the skin and eyes in some people.

However, when used in appropriate concentrations and according to recommended guidelines, it is generally considered to be safe for use in personal care products.
Rhodapon LS-92/RN has a chemical structure due to which it is classified as a member of a large group of compounds called surfactants.
Surfactant particles surround dirt, which makes its particles detach from the cleaned surface, from which they are then rinsed off with water.

In addition, the good foaming properties of this compound enhance the cleansing effect and the feeling of freshness after application.
The cleaning properties of Rhodapon LS-92/RN are directly related to its ability to produce large amounts of stable foam.
The ability to produce dense and stable foam allows to obtain fine and evenly distributed air bubbles.

Foam is a system where air (or other gas) is dispersed in a liquid.
Pure liquids do not have the ability to foam, but after adding surfactants, foam formation is observed in such systems.
The foaming capacity of Rhodapon LS-92/RN largely depends on its concentration, the pH value of the solution and the hardness of the water.

Importantly, the good cleaning and foaming properties of Rhodapon LS-92/RN are preserved even in the presence of an excessive amount of sebum.
Rhodapon LS-92/RN is very often used as a substitute for irritating detergents such as SLS (Sodium Lauryl Sulphate).
However, Rhodapon LS-92/RN can also be irritating to the skin and mucous membranes, which is why it is most often used together with other substances that balance its effects.

Rhodapon LS-92/RN is a mild cleanser and surfactant that is used as a foaming agent in shampoos, shaving foam, toothpaste, and other skincare products.
It is extremely beneficial for people with sensitive skin and mild skin issues.

Safety profile:
Rhodapon LS-92/RNs exhibit low acute oral toxicity, no toxicity through exposure to the skin, concentration dependent skin irritation, and concentration dependent eye-irritation.
They do not sensitize the skin and did not appear to be carcinogenic in a two-year study on rats.
The report found that longer carbon chains (16–18) were less irritating to the skin than chains of 12–15 carbons in length.

In addition, concentrations below 1% were essentially non-irritating while concentrations greater than 10% produced moderate to strong irritation of the skin.
Rhodapon LS-92/RN is considered safe for cosmetic use when used in appropriate concentrations.
However, in high concentrations, it may cause mild skin and eye irritation for some individuals.

Therefore, proper regulation during manufacturing and patch testing before use becomes important.
Rhodapon LS-92/RN is an innocuous detergent.
A 1983 report by the Cosmetic Ingredient Review, shampoos containing up to 31% Rhodapon LS-92/RN registered 6 health complaints out of 6.8 million units sold.

These complaints included two of scalp itch, two allergic reactions, one hair damage and one complaint of eye irritation.
The CIR report concluded that both sodium and ammonium lauryl sulfate "appear to be safe in formulations designed for discontinuous, brief use followed by thorough rinsing from the surface of the skin.

In products intended for prolonged use, concentrations should not exceed 1%".
The Human and Environmental Risk Assessment (HERA) project performed a thorough investigation of all alkyl sulfates, as such the results they found apply directly to Rhodapon LS-92/RN.


RHODIOLA ROSEA EXTRACT

Rhodiola Rosea Extract, derived from the root of Rhodiola rosea, is known for its adaptogenic, antioxidant, and anti-fatigue properties.
Rhodiola Rosea Extract is widely recognized for its ability to reduce stress, improve cognitive function, and enhance physical endurance, making it a valuable ingredient in dietary supplements and wellness formulations.
This versatile extract offers both therapeutic and wellness benefits, helping to support mental clarity, improve energy levels, and enhance overall resilience to stress.

CAS Number: 97404-52-9
EC Number: 307-922-2

Synonyms: Rhodiola Extract, Rhodiola Rosea Root Extract, Golden Root Extract, Arctic Root Extract, Rosavin Extract, Rhodiola Herbal Extract, Rhodiola Phytocomplex, Rhodiola Bioactive Extract, Golden Root Phytocomplex, Rhodiola Rosea Root Active



APPLICATIONS


Rhodiola Rosea Extract is extensively used in stress-relief supplements, offering adaptogenic benefits that help the body cope with physical and mental stress while promoting overall relaxation.
Rhodiola Rosea Extract is favored in the formulation of energy-boosting supplements, where it helps to improve stamina, reduce fatigue, and enhance physical endurance, making it popular among athletes and active individuals.
Rhodiola Rosea Extract is utilized in the development of cognitive function supplements, providing benefits for enhancing focus, memory, and mental clarity.

Rhodiola Rosea Extract is widely used in dietary supplements for its ability to support mental well-being, helping to alleviate symptoms of anxiety and depression by balancing neurotransmitter levels.
Rhodiola Rosea Extract is employed in the creation of mood-enhancing supplements, offering natural support for reducing mood swings and promoting emotional stability.
Rhodiola Rosea Extract is essential in the development of nootropic products, where it helps to boost mental performance and increase resistance to cognitive fatigue during stressful situations.

Rhodiola Rosea Extract is utilized in the production of supplements designed to improve immune function, providing antioxidant protection and enhancing the body’s resilience to infections and illness.
Rhodiola Rosea Extract is a key ingredient in wellness supplements aimed at enhancing overall vitality, reducing burnout, and improving general well-being.
Rhodiola Rosea Extract is used in the development of adaptogen complexes, where it is combined with other adaptogenic herbs to provide comprehensive support for stress management and energy balance.

Rhodiola Rosea Extract is applied in the formulation of anti-fatigue supplements, where it helps to reduce exhaustion and improve recovery times after physical exertion or mental strain.
Rhodiola Rosea Extract is employed in the production of anti-stress teas and beverages, offering adaptogenic support to help the body resist the damaging effects of stress.
Rhodiola Rosea Extract is used in the development of brain health supplements, where it supports neuroprotection, enhances cognitive function, and promotes long-term brain health.

Rhodiola Rosea Extract is widely utilized in anti-aging supplements for its antioxidant properties, helping to protect cells from oxidative damage and promote healthy aging.
Rhodiola Rosea Extract is a key component in weight management supplements, where it helps to regulate metabolism, reduce stress-related cravings, and support healthy weight loss.
Rhodiola Rosea Extract is used in sleep-support supplements, helping to improve sleep quality and reduce insomnia by calming the nervous system and reducing stress.

Rhodiola Rosea Extract is employed in the formulation of post-exercise recovery products, providing support for muscle recovery, reducing soreness, and improving endurance for future activities.
Rhodiola Rosea Extract is applied in supplements designed to boost physical performance, offering athletes and fitness enthusiasts enhanced stamina, reduced fatigue, and improved strength during workouts.
Rhodiola Rosea Extract is utilized in the creation of wellness drinks, offering benefits for increasing energy, promoting relaxation, and enhancing mental clarity.

Rhodiola Rosea Extract is found in mood-regulating supplements, where it helps to balance hormone levels and reduce symptoms of stress-related disorders, such as adrenal fatigue.
Rhodiola Rosea Extract is used in the production of mental resilience supplements, offering support for maintaining cognitive function under high-stress conditions.
Rhodiola Rosea Extract is a key ingredient in supplements designed to support overall resilience to emotional and physical stress, making it an ideal choice for individuals experiencing chronic stress or burnout.

Rhodiola Rosea Extract is employed in the development of supplements for improving work performance, offering benefits for enhancing focus, concentration, and productivity.
Rhodiola Rosea Extract is applied in natural remedies for reducing the symptoms of depression and anxiety, offering natural support for mental health.
Rhodiola Rosea Extract is utilized in wellness products aimed at improving cardiovascular health, where it helps to regulate blood pressure and support healthy circulation.

Rhodiola Rosea Extract is found in supplements for reducing stress-related digestive issues, such as indigestion, bloating, and stomach discomfort.
Rhodiola Rosea Extract is used in post-trauma recovery supplements, helping to reduce mental and emotional exhaustion following physically or emotionally demanding situations.
Rhodiola Rosea Extract is a key ingredient in nootropic formulas that support mental alertness, cognitive flexibility, and problem-solving under pressure.



DESCRIPTION


Rhodiola Rosea Extract, derived from the root of Rhodiola rosea, is known for its adaptogenic, antioxidant, and anti-fatigue properties.
Rhodiola Rosea Extract is widely recognized for its ability to reduce stress, improve cognitive function, and enhance physical endurance, making it a valuable ingredient in dietary supplements and wellness formulations.

Rhodiola Rosea Extract offers additional benefits such as boosting mental clarity, improving mood, and supporting immune health.
Rhodiola Rosea Extract is often incorporated into formulations designed to enhance physical and mental performance, making it an ideal choice for athletes and individuals dealing with high levels of stress.
Rhodiola Rosea Extract is recognized for its ability to protect cells from oxidative damage, helping to prevent premature aging and improve overall vitality.

Rhodiola Rosea Extract is commonly used in both traditional and modern wellness formulations, providing a reliable solution for managing stress, enhancing energy levels, and improving cognitive performance.
Rhodiola Rosea Extract is valued for its ability to improve the body's resilience to physical and emotional stress, making it an ideal ingredient for stress-management and anti-fatigue products.
Rhodiola Rosea Extract is a versatile ingredient that can be used in a variety of products, including supplements, teas, capsules, and nootropic formulations.

Rhodiola Rosea Extract is an ideal choice for products targeting stress relief, cognitive enhancement, and physical endurance, providing natural and effective care for these concerns.
Rhodiola Rosea Extract is known for its compatibility with other adaptogenic and cognitive-supporting ingredients, allowing it to be easily integrated into multi-functional formulations.
Rhodiola Rosea Extract is often chosen for formulations requiring a balance between mental and physical stress relief, energy enhancement, and immune support, ensuring comprehensive wellness benefits.

Rhodiola Rosea Extract enhances the overall effectiveness of wellness products by providing natural support for reducing fatigue, improving mental performance, and promoting relaxation.
Rhodiola Rosea Extract is a reliable ingredient for creating products that offer noticeable improvements in stress management, cognitive function, and physical endurance.
Rhodiola Rosea Extract is an essential component in innovative wellness products known for their performance, safety, and ability to support stress resilience, cognitive health, and overall vitality.



PROPERTIES


Chemical Formula: N/A (Natural extract)
Common Name: Rhodiola Rosea Extract (Rhodiola rosea Extract)
Molecular Structure:
Appearance: Yellow-brown powder or liquid extract
Density: Approx. 1.00-1.05 g/cm³ (for powder)
Melting Point: N/A (powder form)
Solubility: Soluble in water and ethanol; insoluble in oils
Flash Point: >100°C (for powder)
Reactivity: Stable under normal conditions; no known reactivity issues
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store between 15-25°C in a cool, dry place
Vapor Pressure: Low (for liquid extract)



FIRST AID


Inhalation:
If Rhodiola Rosea Extract is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Wash the affected area with soap and water.
If skin irritation persists, seek medical attention.

Eye Contact:
In case of eye contact, flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
If Rhodiola Rosea Extract is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles if handling large quantities.
Use in a well-ventilated area to avoid inhalation of dust.

Ventilation:
Ensure adequate ventilation when handling large amounts of Rhodiola Rosea Extract to control airborne concentrations below occupational exposure limits.

Avoidance:
Avoid direct contact with eyes and prolonged skin contact.
Do not eat, drink, or smoke while handling Rhodiola Rosea Extract.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Contain spills to prevent further release and minimize exposure.
Absorb with inert material (e.g., sand, vermiculite) and collect for disposal.
Dispose of in accordance with local regulations.

Storage:
Store Rhodiola Rosea Extract in a cool, dry, well-ventilated area away from incompatible materials (see SDS for specific details).
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and ignition sources.

Handling Cautions:
Avoid inhalation of dust and direct contact with skin and eyes.
Use explosion-proof equipment in areas where dust or vapors may be present.


Rhodiola rosea
rhodiola rosea extract; extract of the whole plant, rhodiola rosea (l.), crassulaceae; golden root root extract; rhodiola roanensis extract; rhodiola rosea subsp. elongata extract; roseroot extract; sedum rhodiola extract; sedum roanense extract ;sedum rosea extract CAS NO:97404-52-9
RHODODENDRON (SECT. TSUTSUSI) EXTRACT

Rhododendron (sect. Tsutsusi) Extract, derived from the Rhododendron species in the Tsutsusi section, is known for its antioxidant, anti-inflammatory, and antimicrobial properties.
Rhododendron (sect. Tsutsusi) Extract is widely recognized for its ability to protect skin from environmental damage, reduce inflammation, and promote healing, making it a valuable ingredient in skincare, wellness, and traditional medicinal formulations.
This versatile extract offers both therapeutic and cosmetic benefits, helping to soothe irritated skin, improve skin elasticity, and support overall wellness.

CAS Number: N/A (specific CAS number for extract varies by processing method)
EC Number: N/A (specific EC number for extract varies by processing method)

Synonyms: Rhododendron Extract, Tsutsusi Extract, Rhododendron sect. Tsutsusi Extract, Azalea Extract, Rhododendron Herbal Extract, Tsutsusi Phytocomplex, Rhododendron Bioactive Extract, Azalea Phytocomplex, Rhododendron Active, Tsutsusi Flower Extract



APPLICATIONS


Rhododendron (sect. Tsutsusi) Extract is extensively used in skincare formulations for its antioxidant properties, helping to protect the skin from free radical damage and environmental stressors like pollution and UV rays.
Rhododendron (sect. Tsutsusi) Extract is favored in anti-aging creams, where it helps to improve skin elasticity, reduce fine lines, and restore firmness by promoting collagen production.
Rhododendron (sect. Tsutsusi) Extract is utilized in the development of soothing lotions, offering relief from inflammation and irritation, making it suitable for sensitive or reactive skin.

Rhododendron (sect. Tsutsusi) Extract is widely used in traditional herbal remedies for its antimicrobial properties, which help to reduce infections, improve wound healing, and promote skin health.
Rhododendron (sect. Tsutsusi) Extract is employed in the creation of herbal teas and wellness beverages, offering antioxidant benefits and supporting overall immune function.
Rhododendron (sect. Tsutsusi) Extract is essential in the development of products designed to calm and heal skin conditions such as eczema, rosacea, and dermatitis, offering natural anti-inflammatory relief.

Rhododendron (sect. Tsutsusi) Extract is utilized in the production of anti-inflammatory supplements, offering natural support for reducing chronic inflammation and improving joint health.
Rhododendron (sect. Tsutsusi) Extract is a key ingredient in holistic wellness products designed to detoxify the skin, providing cleansing benefits and promoting overall skin health.
Rhododendron (sect. Tsutsusi) Extract is used in the development of skin-brightening creams, where it helps to even out skin tone and lighten hyperpigmentation caused by sun exposure or aging.

Rhododendron (sect. Tsutsusi) Extract is applied in the formulation of toners and serums, offering hydration, calming effects, and antioxidant protection to keep the skin looking youthful and refreshed.
Rhododendron (sect. Tsutsusi) Extract is employed in the creation of anti-redness treatments, helping to reduce visible signs of inflammation, irritation, and sensitivity in the skin.
Rhododendron (sect. Tsutsusi) Extract is used in wellness supplements that support immune health, offering benefits for boosting the body’s natural defenses and improving overall vitality.

Rhododendron (sect. Tsutsusi) Extract is widely utilized in the formulation of anti-pollution skincare products, where it helps to protect the skin from environmental pollutants and promote detoxification.
Rhododendron (sect. Tsutsusi) Extract is a key component in herbal compresses and topical treatments designed to soothe inflamed skin and promote wound healing.
Rhododendron (sect. Tsutsusi) Extract is used in the production of after-sun care products, providing relief from UV-induced skin damage and helping to repair sunburned skin.

Rhododendron (sect. Tsutsusi) Extract is employed in the creation of scalp treatments for sensitive skin, providing soothing, anti-inflammatory benefits and promoting a healthy scalp.
Rhododendron (sect. Tsutsusi) Extract is applied in the development of body creams and lotions aimed at improving skin texture, elasticity, and hydration for dry and mature skin types.
Rhododendron (sect. Tsutsusi) Extract is utilized in the production of cosmetic products that promote skin regeneration, offering benefits for reducing scars and accelerating skin healing.

Rhododendron (sect. Tsutsusi) Extract is found in wellness products aimed at enhancing respiratory health, offering natural support for reducing symptoms of bronchitis, colds, and other respiratory infections.
Rhododendron (sect. Tsutsusi) Extract is used in detoxifying beauty masks, helping to draw out impurities, clear clogged pores, and leave the skin feeling refreshed and purified.
Rhododendron (sect. Tsutsusi) Extract is a key ingredient in bath soaks and oils, providing soothing and calming effects that help to relax the body and relieve muscle tension.



DESCRIPTION


Rhododendron (sect. Tsutsusi) Extract, derived from the Rhododendron species in the Tsutsusi section, is known for its antioxidant, anti-inflammatory, and antimicrobial properties.
Rhododendron (sect. Tsutsusi) Extract is widely recognized for its ability to protect skin from environmental damage, reduce inflammation, and promote healing, making it a valuable ingredient in skincare, wellness, and traditional medicinal formulations.

Rhododendron (sect. Tsutsusi) Extract offers additional benefits such as improving skin tone, reducing redness, and providing relief from inflammatory skin conditions.
Rhododendron (sect. Tsutsusi) Extract is often incorporated into formulations designed to promote skin regeneration, protect against UV-induced skin damage, and support overall skin health.
Rhododendron (sect. Tsutsusi) Extract is recognized for its ability to soothe sensitive skin, making it ideal for formulations aimed at reducing redness and irritation caused by environmental aggressors.

Rhododendron (sect. Tsutsusi) Extract is commonly used in both traditional and modern wellness formulations, providing a reliable solution for protecting the skin, promoting healing, and reducing inflammation.
Rhododendron (sect. Tsutsusi) Extract is valued for its ability to offer antimicrobial benefits, helping to treat and prevent skin infections while supporting wound healing.
Rhododendron (sect. Tsutsusi) Extract is a versatile ingredient that can be used in a variety of products, including creams, serums, toners, supplements, and wellness teas.

Rhododendron (sect. Tsutsusi) Extract is an ideal choice for products targeting inflammation, oxidative stress, and environmental protection, providing natural and effective care for these concerns.
Rhododendron (sect. Tsutsusi) Extract is known for its compatibility with other skin-soothing and antioxidant-rich ingredients, allowing it to be easily integrated into multi-functional formulations.
Rhododendron (sect. Tsutsusi) Extract is often chosen for formulations requiring a balance between calming, healing, and antimicrobial care, ensuring comprehensive skin protection and wellness benefits.

Rhododendron (sect. Tsutsusi) Extract enhances the overall effectiveness of skincare and wellness products by providing natural support for protecting the skin, calming irritation, and promoting detoxification.
Rhododendron (sect. Tsutsusi) Extract is a reliable ingredient for creating products that offer noticeable improvements in skin clarity, elasticity, and overall radiance.
Rhododendron (sect. Tsutsusi) Extract is an essential component in innovative skincare and wellness products known for their performance, safety, and ability to support sensitive skin, wound healing, and overall vitality.



PROPERTIES


Chemical Formula: N/A (Natural extract)
Common Name: Rhododendron Extract (Rhododendron sect. Tsutsusi Extract)
Molecular Structure:
Appearance: Yellow-brown to amber liquid or powder extract
Density: Approx. 1.00-1.05 g/cm³ (for powder)
Melting Point: N/A (powder form)
Solubility: Soluble in water and ethanol; insoluble in oils
Flash Point: >100°C (for powder)
Reactivity: Stable under normal conditions; no known reactivity issues
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store between 15-25°C in a cool, dry place
Vapor Pressure: Low (for liquid extract)



FIRST AID


Inhalation:
If Rhododendron (sect. Tsutsusi) Extract is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Wash the affected area with soap and water.
If skin irritation persists, seek medical attention.

Eye Contact:
In case of eye contact, flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
If Rhododendron (sect. Tsutsusi) Extract is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles if handling large quantities.
Use in a well-ventilated area to avoid inhalation of dust.

Ventilation:
Ensure adequate ventilation when handling large amounts of Rhododendron (sect. Tsutsusi) Extract to control airborne concentrations below occupational exposure limits.

Avoidance:
Avoid direct contact with eyes and prolonged skin contact.
Do not eat, drink, or smoke while handling Rhododendron (sect. Tsutsusi) Extract.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Contain spills to prevent further release and minimize exposure.
Absorb with inert material (e.g., sand, vermiculite) and collect for disposal.
Dispose of in accordance with local regulations.

Storage:
Store Rhododendron (sect. Tsutsusi) Extract in a cool, dry, well-ventilated area away from incompatible materials (see SDS for specific details).
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and ignition sources.

Handling Cautions:
Avoid inhalation of dust and direct contact with skin and eyes.
Use explosion-proof equipment in areas where dust or vapors may be present.

RHUS CHINENSIS (CHINESE GALL) EXTRACT

Rhus chinensis (Chinese Gall) Extract, derived from the galls of Rhus chinensis, is known for its powerful astringent, antioxidant, and antimicrobial properties.
Rhus chinensis (Chinese Gall) Extract is widely recognized for its use in traditional medicine for treating infections, digestive disorders, and skin ailments, making it a valuable ingredient in health and skincare formulations.
This versatile extract offers therapeutic benefits, helping to reduce inflammation, combat bacterial infections, and promote wound healing.

CAS Number: 90045-47-9
EC Number: 289-800-8

Synonyms: Chinese Gall Extract, Rhus chinensis Gall Extract, Galla Chinensis Extract, Chinese Gallnut Extract, Nutgall Extract, Gallnut Herbal Extract, Chinese Gall Phytocomplex, Rhus chinensis Bioactive Extract, Gallnut Phytocomplex, Chinese Gallnut Active



APPLICATIONS


Rhus chinensis (Chinese Gall) Extract is extensively used in traditional herbal medicine for its astringent properties, helping to treat digestive disorders such as diarrhea and dysentery by toning the intestinal lining.
Rhus chinensis (Chinese Gall) Extract is favored in the formulation of antimicrobial skincare products, where it helps to reduce bacterial growth, making it ideal for treating acne and preventing infections.
Rhus chinensis (Chinese Gall) Extract is utilized in the development of wound-healing formulations, offering natural support for promoting faster healing and preventing infections in minor cuts and abrasions.

Rhus chinensis (Chinese Gall) Extract is widely used in oral care products for its antimicrobial benefits, helping to reduce bacteria in the mouth, prevent cavities, and treat gum infections.
Rhus chinensis (Chinese Gall) Extract is employed in the creation of skin-toning lotions and creams, offering astringent benefits that help to tighten pores, reduce excess oil, and improve overall skin texture.
Rhus chinensis (Chinese Gall) Extract is essential in the development of antioxidant-rich formulations designed to protect the skin from environmental stressors and reduce signs of aging.

Rhus chinensis (Chinese Gall) Extract is utilized in the production of anti-inflammatory supplements, offering relief for conditions such as colitis, gastritis, and other inflammatory digestive disorders.
Rhus chinensis (Chinese Gall) Extract is a key ingredient in holistic wellness products that support liver detoxification, helping to eliminate toxins and promote healthy liver function.
Rhus chinensis (Chinese Gall) Extract is used in the development of hair care products designed to treat scalp conditions such as dandruff, providing antimicrobial support and soothing irritation.

Rhus chinensis (Chinese Gall) Extract is applied in the formulation of topical treatments for skin infections and wounds, offering natural antimicrobial and healing benefits.
Rhus chinensis (Chinese Gall) Extract is employed in the creation of natural remedies for gastrointestinal health, offering support for treating stomach ulcers, intestinal inflammation, and other digestive issues.
Rhus chinensis (Chinese Gall) Extract is used in skincare products targeting hyperpigmentation, where it helps to lighten dark spots and improve skin tone.

Rhus chinensis (Chinese Gall) Extract is widely utilized in anti-aging skincare products for its antioxidant properties, helping to reduce wrinkles and prevent the premature breakdown of collagen.
Rhus chinensis (Chinese Gall) Extract is a key component in acne treatments, where its astringent and antibacterial effects help to reduce inflammation, control oil production, and prevent breakouts.
Rhus chinensis (Chinese Gall) Extract is used in oral health supplements to support the treatment of periodontal disease, reducing inflammation in the gums and protecting against bacteria.

Rhus chinensis (Chinese Gall) Extract is employed in the development of detox products, where it supports cleansing of the digestive system and promotes the elimination of harmful bacteria and parasites.
Rhus chinensis (Chinese Gall) Extract is applied in the formulation of foot care products for treating athlete’s foot and fungal infections, providing antimicrobial protection and soothing irritated skin.
Rhus chinensis (Chinese Gall) Extract is utilized in traditional remedies for treating respiratory infections, offering benefits for reducing inflammation and fighting bacterial growth in the respiratory tract.

Rhus chinensis (Chinese Gall) Extract is found in anti-inflammatory teas and supplements aimed at improving digestive health and supporting immune function.
Rhus chinensis (Chinese Gall) Extract is used in oral rinses and gargles, offering astringent and antimicrobial benefits for treating sore throats, mouth ulcers, and gum infections.
Rhus chinensis (Chinese Gall) Extract is a key ingredient in wellness products designed to reduce inflammation throughout the body, offering benefits for conditions such as arthritis and inflammatory bowel disease.



DESCRIPTION


Rhus chinensis (Chinese Gall) Extract, derived from the galls of Rhus chinensis, is known for its powerful astringent, antioxidant, and antimicrobial properties.
Rhus chinensis (Chinese Gall) Extract is widely recognized for its use in traditional medicine for treating infections, digestive disorders, and skin ailments, making it a valuable ingredient in health and skincare formulations.

Rhus chinensis (Chinese Gall) Extract offers additional benefits such as promoting wound healing, supporting liver health, and improving oral hygiene by reducing bacterial growth.
Rhus chinensis (Chinese Gall) Extract is often incorporated into formulations designed to treat inflammatory digestive conditions, protect the skin from bacterial infections, and promote healing.
Rhus chinensis (Chinese Gall) Extract is recognized for its ability to reduce excess oil production in the skin, making it ideal for acne treatments and oily skin formulations.

Rhus chinensis (Chinese Gall) Extract is commonly used in both traditional and modern wellness formulations, providing a reliable solution for treating infections, supporting digestive health, and promoting skin healing.
Rhus chinensis (Chinese Gall) Extract is valued for its ability to tone and tighten the skin, making it a popular ingredient in anti-aging and pore-refining skincare products.
Rhus chinensis (Chinese Gall) Extract is a versatile ingredient that can be used in a variety of products, including skincare formulations, oral care products, supplements, and topical treatments.

Rhus chinensis (Chinese Gall) Extract is an ideal choice for products targeting infections, inflammation, and skin healing, providing natural and effective care for these concerns.
Rhus chinensis (Chinese Gall) Extract is known for its compatibility with other antimicrobial and antioxidant-rich ingredients, allowing it to be easily integrated into multi-functional formulations.
Rhus chinensis (Chinese Gall) Extract is often chosen for formulations requiring a balance between astringent, antimicrobial, and anti-inflammatory benefits, ensuring comprehensive wellness and skincare support.

Rhus chinensis (Chinese Gall) Extract enhances the overall effectiveness of skincare, digestive health, and wellness products by providing natural support for reducing inflammation, promoting healing, and protecting against bacterial infections.
Rhus chinensis (Chinese Gall) Extract is a reliable ingredient for creating products that offer noticeable improvements in skin clarity, digestive health, and oral hygiene.
Rhus chinensis (Chinese Gall) Extract is an essential component in innovative wellness and skincare products known for their performance, safety, and ability to support skin, digestive, and immune health.



PROPERTIES


Chemical Formula: N/A (Natural extract)
Common Name: Rhus chinensis Extract (Chinese Gall Extract)
Molecular Structure:
Appearance: Light brown to dark brown powder or liquid extract
Density: Approx. 1.00-1.05 g/cm³ (for powder)
Melting Point: N/A (powder form)
Solubility: Soluble in water and ethanol; insoluble in oils
Flash Point: >100°C (for powder)
Reactivity: Stable under normal conditions; no known reactivity issues
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store between 15-25°C in a cool, dry place
Vapor Pressure: Low (for liquid extract)



FIRST AID


Inhalation:
If Rhus chinensis (Chinese Gall) Extract is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Wash the affected area with soap and water.
If skin irritation persists, seek medical attention.

Eye Contact:
In case of eye contact, flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
If Rhus chinensis (Chinese Gall) Extract is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles if handling large quantities.
Use in a well-ventilated area to avoid inhalation of dust.

Ventilation:
Ensure adequate ventilation when handling large amounts of Rhus chinensis (Chinese Gall) Extract to control airborne concentrations below occupational exposure limits.

Avoidance:
Avoid direct contact with eyes and prolonged skin contact.
Do not eat, drink, or smoke while handling Rhus chinensis (Chinese Gall) Extract.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Contain spills to prevent further release and minimize exposure.
Absorb with inert material (e.g., sand, vermiculite) and collect for disposal.
Dispose of in accordance with local regulations.

Storage:
Store Rhus chinensis (Chinese Gall) Extract in a cool, dry, well-ventilated area away from incompatible materials (see SDS for specific details).
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and ignition sources.

Handling Cautions:
Avoid inhalation of dust and direct contact with skin and eyes.
Use explosion-proof equipment in areas where dust or vapors may be present.

RIBOFLAVIN
SYNONYMS 7,8-Dimethyl-10-ribitylisoalloxazine; 3,10-Dihydro-7,8-dimetyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl] benzo[g]pteridine-2,4-dione; Ovoflavin; Zinvit-G; Riboflavin; Lactoflavin; Vitamin B2; 6,7-Dimethyl-9-D-ribitylisoalloxazine, 7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine; 7,8-Dimethyl-10-ribitylisoalloxazine; Aqua-Flave; Beflavin; Beflavine; 7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)- benzo(g) pteridine-2,4(3H,10H)-dione; 1-Deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo(g)pteridin- 10(2H)-yl)-D-ribitol; Dermadram; Fiboflavin; Flavaxin; Flavin BB; Flaxain; Hyflavin; 7,8-Dimethyl-10- (D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine; 7,8-Dimethyl-10-D-ribitylisoalloxazine; Lactobene; Lactoflavin; Lactoflavine; Ribipca; Ribocrisina; Riboderm; Riboflavin; Riboflavina; Riboflavine; Riboflavinequinone; Riboflavinum; Ribosyn; Ribotone; Ribovel; Russupteridine Yellow III; Vitaflavine; Vitamin B2 ; Vitamin Bi; Vitamin G; Vitasan B2 RIBOFLAVIN CAS :83-88-5
RIBOFLAVIN TETRABUTYRATE
RICINOLEAMIDE DEA N° CAS : 40716-42-5 Nom INCI : RICINOLEAMIDE DEA Nom chimique : [R-(Z)]-12-Hydroxy-N,N-bis(2-hydroxyethyl)-9-octadecenamide N° EINECS/ELINCS : 255-051-3 Classification : Règlementé, DEA Restriction en Europe : III/60 Ses fonctions (INCI) Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface Sinergiste de mousse : Améliore la qualité de la mousse produite en augmentant une ou plusieurs des propriétés suivantes: volume, texture et / ou stabilité Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques
RIBONUCLEOTIDE
Ribonucleotide is considered a molecular precursor of nucleic acids.
Ribonucleotide contains approximately 7.5 molecules of water of crystallization.
Ribonucleotide is odorless and has characteristic taste.

CAS Number: 4691-65-0
Molecular Formula: C10H14N4NaO8P
Molecular Weight: 372.21
EINECS Number: 225-146-4

4691-65-0, Disodium 5'-inosinate, Disodium inosinate, Sodium inosinate, 5'-Imp disodium salt, IMP disodium salt, 5'-INOSINIC ACID, DISODIUM SALT, Inosine-5'-monophosphoric acid disodium salt, FEMA No. 3669, Inosine 5'-monophosphate disodium salt, Disodium inosine-5'-monophosphate, Inosine 5'-monophosphate disodium, Inosine-5'-monophosphate disodium, Inosine 5'-monophosphate disodium salt hydrate, Sodium 5'-inosinate, T2ZYA7KC05, 5'-Inosinic acid, sodium salt (1:2), IMP sodium salt, disodium;[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl phosphate, Sodium Inosine 5'-Phosphate (2:1), Disodium inosine 5'-monophosphate, Ribotide, Disodium inosine 5'-phosphate, 5'-Inosinic Acid Disodium Salt, sodium ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl phosphate, MFCD00036201, CCRIS 6560, 5'-IMPdisodium salt, Inosin-5'-monophosphate disodium, EINECS 225-146-4, NSC 20263, Inosic Acid Disodium Salt, UNII-T2ZYA7KC05, 5'-IMP 2Na, Inosine-5'-monophosphate sodium salt, NSC-20263, inosine 5'-monophosphoric acid disodium salt, Inosine monophosphate disodium, SCHEMBL316941, INS NO.631, DISODIUM INOSINATE [FCC], DTXSID4044242, DISODIUM INOSINATE [INCI], INS-631, CHEBI:184785, DISODIUM INOSINATE [MART.], DISODIUM INOSINATE [USP-RS], DISODIUM INOSINATE [WHO-DD], Inosine-5'-monophosphateDisodiumSalt, AKOS015896269, AKOS015918501, AKOS024282555, DISODIUM 5'-INOSINATE [FHFI], CCG-268550, E 631 (FOOD ENHANCEMENT AGENT), Inosine monophosphate disodium [WHO-DD], [(3S,2R,4R,5R)-3,4-dihydroxy-5-(6-oxohydropurin-9-yl)oxolan-2-yl]methyl dihydr ogen phosphate, sodium salt, sodium salt, AS-57564, E 631, E-631, I0036, Q905782, disodium [(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-9H-purin-9-yl)oxolan-2-yl]methyl phosphate, sodium ((2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-2-yl)methyl phosphate

Ribonucleotide, formed by reducing ribonucleotides with the enzyme ribonucleotide reductase (RNR), are essential building blocks for DNA.
There are several differences between DNA deoxyribonucleotides and RNA ribonucleotides.
Successive nucleotides are linked together via phosphodiester bonds.

In biochemistry, a Ribonucleotide is a nucleotide containing ribose as its pentose component.
Nucleotides are the basic building blocks of DNA and RNA.
Ribonucleotides themselves are basic monomeric building blocks for RNA.

Ribonucleotides are also utilized in other cellular functions.
These special monomers are utilized in both cell regulation and cell signaling as seen in adenosine-monophosphate (AMP).
Furthermore, ribonucleotides can be converted to adenosine triphosphate (ATP), the energy currency in organisms.

Ribonucleotides can be converted to cyclic adenosine monophosphate (cyclic AMP) to regulate hormones in organisms as well.
In living organisms, the most common bases for ribonucleotides are adenine (A), guanine (G), cytosine (C), or uracil (U).
The nitrogenous bases are classified into two parent compounds, purine and pyrimidine.

The general structure of a ribonucleotide consists of a phosphate group, a ribose sugar group, and a nucleobase, in which the nucleobase can either be adenine, guanine, cytosine, or uracil.
Without the phosphate group, the composition of the nucleobase and sugar is known as a nucleoside.
The interchangeable nitrogenous nucleobases are derived from two parent compounds, purine and pyrimidine.

Nucleotides are Ribonucleotide compounds, that is, they contain at least two different chemical elements as members of its rings.
Both RNA and DNA contain two major purine bases, adenine (A) and guanine (G), and two major pyrimidines.
In both DNA and RNA, one of the pyrimidines is cytosine (C).

However, DNA and RNA differ in the second major pyrimidine.
DNA contains thymine (T) while RNA contains uracil (U).
There are some rare cases where thymine does occur in RNA and uracil in DNA.

Ribonucleotides can be synthesized in organisms from smaller molecules through the de novo pathway or recycled through the salvage pathway.
In the case of the de novo pathway, both purines and pyrimidines are synthesized from components derived from precursors of amino acids, ribose-5-phosphates, CO2, and NH3.
Ribonucleotides are the building blocks of nucleic acids — one of the four essential groups of biomolecules among proteins, carbohydrates, and amino acids.

The basic skeleton of Ribonucleotide is made of pentose sugar, phosphate, and a nitrogenous base (purine or pyrimidine).
And, based on the type of pentose sugar the nucleotide contains, Ribonucleotide’s of two types: ribonucleotide and deoxyribonucleotide.

Ribonucleotide is a nucleotide having ribose as its pentose sugar.
Ribonucleotide molecule acts as a precursor for nucleic acid synthesis.
Ribonucleotide can be transformed into deoxyribose sugar after the reduction reaction facilitated by ribonucleotide reductase (RNR) — an enzyme first discovered in E.coli (Escherichia coli) and has a catalytic mechanism in ribonucleotide reduction.

The ribonucleotide is mainly used for the synthesis of RNA.
Whereas deoxyribonucleotide is used in the DNA synthesis process.
The nitrogenous bases of ribonucleotides are grouped into two groups: purine and pyrimidine.

They consist of four molecules, which include adenine (A), guanine (G), cytosine (C), and uracil (U).
The difference between DNA and RNA developing nucleotides is the presence of thymine, which is only involved in the DNA replication process and not in RNA synthesis.
The presence and absence of phosphate groups in the ribonucleotide structure change the whole chemistry of the biomolecule.

In absence of a phosphate group, the molecule is known as ribonucleoside rather than ribonucleotides.
Also, based on the number of phosphates, ribonucleotides can be monophosphates (having one phosphate group), diphosphates (having two phosphate groups), and triphosphates (having three phosphate groups).
Ribonucleotide, also known as ribonucleoside diphosphate reductase (rNDP), is an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides.

Ribonucleotide catalyzes this formation by removing the 2'-hydroxyl group of the ribose ring of nucleoside diphosphates.
This reduction produces deoxyribonucleotides.
Ribonucleotides in turn are used in the synthesis of DNA.

The reaction catalyzed by RNR is strictly conserved in all living organisms.
Furthermore, RNR plays a critical role in regulating the total rate of DNA synthesis so that DNA to cell mass is maintained at a constant ratio during cell division and DNA repair.
A somewhat unusual feature of the RNR enzyme is that it catalyzes a reaction that proceeds via a free radical mechanism of action.

The substrates for RNR are ADP, GDP, CDP and UDP, dTDP (deoxythymidine diphosphate) is synthesized by another enzyme (thymidylate kinase) from dTMP (deoxythymidine monophosphate).
Ribonucleotides contain a pentose sugar called ribose, which has five carbon atoms.
The ribose sugar serves as the backbone of the ribonucleotide molecule.

Ribonucleotides contain one of four nitrogenous bases: adenine (A), guanine (G), cytosine (C), or uracil (U).
These bases are responsible for the genetic information encoded in RNA molecules.
Ribonucleotides also contain one or more phosphate groups attached to the ribose sugar.

The phosphate groups are responsible for linking individual ribonucleotide units together to form RNA chains.
Ribonucleotides serve as the building blocks for mRNA molecules, which carry genetic information from the DNA in the cell nucleus to the ribosomes, where proteins are synthesized.
Ribonucleotides are involved in the synthesis and modification of tRNA and rRNA molecules, which are essential for protein synthesis.

Ribonucleotides, particularly small RNA molecules such as microRNAs (miRNAs) and small interfering RNAs (siRNAs), play key roles in regulating gene expression by modulating mRNA stability and translation.
Certain ribonucleotides, such as cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), function as second messengers in cell signaling pathways, mediating responses to extracellular signals.
Ribonucleotides can be synthesized de novo from simple precursor molecules in a series of enzymatic reactions known as the nucleotide biosynthesis pathway.

They can also be obtained from the diet through the consumption of nucleic acids in foods such as meat, fish, dairy products, and vegetables.
Ribonucleotide reductases are divided into three classes.
Class I RNR enzymes are constructed from large alpha subunit and small beta subunits which associate to form an active heterodimeric tetramer.

By reducing NDPs to 2'-dNDPs, the enzyme catalyses the de novo synthesis of deoxyribonucleotides (dNTPs), which are precursors to DNA synthesis and essential for cell proliferation.
Class II Ribonucleotide produce a 5'-deoxyadenosyl radical by homolytic cleavage of the C-Co bond in adenosylcobalamin.
In addition, Class III RNRs contain a stable glycyl radical.

Ribonucleotide is the disodium salt of inosinic acid with the chemical formula C10H11N4Na2O8P.
Ribonucleotide is used as a food additive and often found in instant noodles, potato chips, and a variety of other snacks.
Commercial disodium inosinate may either be obtained from bacterial fermentation of sugars or prepared from animal products.

The Vegetarian Society reports that production from meat or fish is more widespread,but the Vegetarian Resource Group reports that all three "leading manufacturers" claim to use fermentation.
Ribonucleotide, also known as sodium 5'-guanylate and disodium 5'-guanylate, is a natural sodium salt of the flavor enhancing nucleotide guanosine monophosphate (GMP).
Ribonucleotide is a food additive with the E number E627.

Ribonucleotide is commonly used in conjunction with glutamic acid.
As Ribonucleotide is a fairly expensive additive, it is usually not used independently of glutamic acid; if disodium guanylate is present in a list of ingredients but MSG does not appear to be, it is likely that glutamic acid is provided as part of another ingredient such as a processed soy protein complex.
Ribonucleotide is often added to foods in conjunction with disodium inosinate; the combination is known as disodium 5'-ribonucleotides.

Ribonucleotide is produced by fermentation.
Ribonucleotide Disodium inosinate (E631), chemical formula C10H11N2Na2O8P, is the disodium salt of inosinic acid.
Ribonucleotide is a food additive often found in instant noodles, potato chips, and a variety of other snacks.

Ribonucleotide is used as a flavor enhancer, in synergy with monosodium glutamate (also known as MSG; the sodium salt of glutamic acid) to provide the umami taste.
Ribonucleotide is a colorless to white crystal or crystalline powder with a characteristic taste.
Ribonucleotide Flavor Enhancer is soluble in water while slightly soluble in alcohol.

Flavor Enhancer E631 is often added to foods in conjunction with E627 Flavour Enhancer and the combination is known as disodium ribonucleotides (I+G).
Ribonucleotide Halal Food Additive is widely used in instant noodles, potato chips and other snacks, savory rice, tinned vegetables, cured meats and packaged soup.

Sinofi is a reliable Ribonucleotide supplier and manufacturer in China.
Ribonucleotide, obtained from bacterial fermentation of sugars, is as a food additive and often found in a variety of other snacks.

Melting point: 175 °C
FEMA: 3669 | DISODIUM 5-INOSINATE
storage temp.: 2-8°C
form: Crystalline Powder
color: White
Odor: odorless
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: -1.02

Ribonucleotide, also known as disodium inosinate or IMP, is a flavor enhancer commonly used in the food industry.
Ribonucleotide is a nucleotide that is naturally present in various foods, including meat, fish, and mushrooms.
Ribonucleotide is also used in medical and industrial research due to its biological activity and potential therapeutic effects.

Ribonucleotides, the sugar component is ribose while in deoxyribonucleotides, the sugar component is deoxyribose.
Instead of a hydroxyl group at the second carbon in the ribose ring, it is replaced by a hydrogen atom.
Both types of pentoses in DNA and RNA are in their β-furanose (closed five-membered ring) form and they define the identity of a nucleic acid.

DNA is defined by containing Ribonucleotide while RNA is defined by containing ribose nucleic acid.
Ribonucleotides have a myriad of functions in organisms, ranging from DNA replication, transcription (the process of mRNA synthesis), DNA repair, and gene expression to acting as a substrate for ATP (adenosine triphosphate) and AMP (adenosine monophosphate) production and metabolic regulation.
The enzyme ribonucleotide reductase (RNR) catalyzes the de novo synthesis of dNDPs.

Catalysis of ribonucleoside 5’-diphosphates (NDPs) involves a reduction at the 2’-carbon of ribose 5-phosphate to form the 2’-deoxy derivative-reduced 2’-deoxyribonucleoside 5’-diphosphates (dNDPs).
This reduction is initiated with the generation of a free radical.
Following a single reduction, RNR requires electrons donated from the dithiol groups of the protein thioredoxin.

Regeneration of thioredoxin occurs when nicotinamide adenine dinucleotide phosphate (NADPH) provides two hydrogen atoms that are used to reduce the disulfide groups of thioredoxin.
Ribonucleotide is naturally found in meat and fish at levels of 80–800 mg/100 g.
Ribonucleotide can also be made by fermentation of sugars such as tapioca starch.

Some sources claim that industrial levels of production are achieved by extraction from animal products, making Ribonucleotide non-vegetarian.
However, an interview by the Vegetarian Resource Group reports that all three "leading manufacturers" (one being Ajinomoto) claims to use an all-vegetarian fermentation process.
Producers are generally open to providing information on the origin.

Ribonucleotide is in some cases labeled as "vegetarian" in ingredients lists when produced from plant sources
Ribonucleotide, known by many names including disodium 5’-guanylate, is derived from a nucleotide, guanosine monophosphate (GMP).
Ribonucleotide is similar to disodium inosinate, also known as disodium 5’-inosinate, which comes from another nucleotide, inosine monophosphate (IMP).

The two together are frequently referred to as 5’-nucleotides (read as “five prime nucleotides.”) Nucleotides are naturally occurring substances found mostly in meats although shiitake mushrooms are also high in nucleotides.
Nucleotides are components of information-carrying molecules (such as DNA) as well as important molecules involved in many diverse aspects of human metabolism.
Ribonucleotides are not only found in mRNA but also in other types of RNA, including transfer RNA (tRNA), ribosomal RNA (rRNA), small nuclear RNA (snRNA), and small nucleolar RNA (snoRNA).

Each type of RNA serves specific functions in gene expression, RNA processing, and protein synthesis.
Ribonucleotides in RNA molecules can undergo various post-transcriptional modifications, such as methylation, pseudouridylation, and base modifications.
These modifications can influence RNA stability, localization, and function.

Ribonucleotides within RNA molecules can form secondary structures, such as hairpins, loops, and stem-loop structures, through complementary base pairing.
These secondary structures play important roles in RNA folding, stability, and interactions with other molecules.
Synthetic analogs of ribonucleotides, such as ribavirin and azidothymidine (AZT), have been developed for therapeutic purposes.

These analogs can interfere with viral replication or DNA synthesis in cancer cells, making them useful in antiviral therapy and chemotherapy.
Ribonucleotides can undergo RNA editing, a process in which specific nucleotides within RNA molecules are enzymatically modified after transcription.
RNA editing can lead to changes in RNA sequence and structure, affecting protein translation and function.

Ribonucleotides are essential components of RNA interference (RNAi) pathways, which regulate gene expression by triggering degradation or translational repression of target mRNAs.
Ribonucleotide has applications in gene silencing, functional genomics, and therapeutic development.
Ribonucleotides are used in the development of RNA-based vaccines, such as messenger RNA (mRNA) vaccines.

These vaccines deliver RNA molecules encoding antigens to host cells, stimulating an immune response against specific pathogens or diseases.
Ribonucleotides can be engineered to form RNA aptamers, which are short RNA sequences that bind to specific target molecules with high affinity and specificity.
Ribonucleotide aptamers have applications in diagnostics, therapeutics, and biochemical research.

Ribonucleotides are involved in the process of RNA splicing, where introns are removed from pre-mRNA molecules to produce mature mRNA transcripts.
Ribonucleotide splicing is mediated by the spliceosome, a complex of ribonucleoprotein particles composed of both RNA and protein.

Uses:
Ribonucleotide is a flavor enhancer which performs as a disodium guanylate does, but only when present at approximately twice the level. see disodium guanylate.
Ribonucleotide is used as a flavor enhancer, in synergy with monosodium glutamate (MSG) to provide the umami taste.
Ribonucleotide is often added to foods in conjunction with disodium guanylate; the combination is known as disodium 5′-ribonucleotides.

As a relatively expensive product, disodium inosinate is usually not used independently of glutamic acid; if disodium inosinate is present in a list of ingredients, but MSG does not appear to be, it is possible that glutamic acid is provided as part of another ingredient or is naturally occurring in another ingredient like tomatoes, Parmesan cheese, or yeast extract.
Ribonucleotides, particularly RNA molecules, are essential for studying gene expression patterns in cells and tissues.

Techniques such as reverse transcription polymerase chain reaction (RT-PCR), RNA sequencing (RNA-seq), and microarray analysis rely on ribonucleotides to detect and quantify RNA transcripts, providing insights into gene regulation and cellular processes.
Ribonucleotides are central to RNA interference (RNAi) technology, which enables specific gene silencing by introducing small interfering RNAs (siRNAs) or short hairpin RNAs (shRNAs) into cells.
Ribonucleotide has applications in functional genomics, target validation, and therapeutic development for treating diseases such as cancer and viral infections.

Ribonucleotides are increasingly used as therapeutics for treating various diseases.
Ribonucleotide vaccines, for example, utilize ribonucleotides to deliver genetic instructions for producing antigens, stimulating immune responses against pathogens such as viruses or cancer cells.
Additionally, RNA interference (RNAi) and antisense oligonucleotide (ASO) therapies target specific disease-causing genes or mRNAs for degradation or inhibition.

Ribonucleotides play crucial roles in biotechnological applications, including the engineering of RNA molecules for research, diagnostics, and therapeutic purposes.
RNA aptamers, riboswitches, and ribozymes are examples of RNA-based tools used in biosensing, drug delivery, and gene regulation.
Ribonucleotides are important targets for drug discovery efforts aimed at developing novel antiviral, anticancer, and antibacterial agents.

Inhibitors of ribonucleotide metabolism enzymes, RNA-processing enzymes, and RNA-protein interactions are being explored as potential drug candidates for various diseases.
Ribonucleotides are utilized in labeling nucleic acids for detection and visualization purposes.
Techniques such as fluorescence in situ hybridization (FISH), northern blotting, and in vitro transcription incorporate ribonucleotides labeled with fluorophores, radioisotopes, or other tags for identifying specific RNA molecules or sequences.

Ribonucleotides are involved in studying RNA modifications, such as methylation, pseudouridylation, and adenosine-to-inosine (A-to-I) editing.
Understanding the roles of RNA modifications in gene regulation, RNA stability, and protein translation has implications for disease mechanisms and therapeutic interventions.
Ribonucleotides are essential reagents in basic biomedical research, facilitating studies on RNA structure, function, and dynamics.

Investigating RNA-protein interactions, RNA folding kinetics, and RNA-mediated signaling pathways contributes to our understanding of cellular physiology and disease mechanisms.
Ribonucleotides, such as cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), serve as important second messengers in cellular signaling pathways.
They mediate intracellular signaling cascades triggered by hormones, neurotransmitters, and other extracellular signals, regulating various cellular processes such as metabolism, ion channel activity, and gene expression.

Ribonucleotides serve as cofactors for numerous enzymes involved in cellular metabolism and biosynthetic pathways.
For example, adenosine triphosphate (ATP), guanosine triphosphate (GTP), and uridine triphosphate (UTP) are essential energy carriers and substrates for enzymes catalyzing phosphorylation reactions, DNA replication, and RNA synthesis.
Ribonucleotides participate in nucleotide salvage pathways, where nucleosides and nucleobases released from RNA degradation or DNA repair are recycled to generate new nucleotides.

These pathways are important for maintaining cellular pools of nucleotides required for DNA and RNA synthesis, especially under conditions of nucleotide deficiency or stress.
Ribonucleotides, such as disodium inosinate (IMP) and disodium guanylate (GMP), are used as flavor enhancers in the food industry to impart umami taste to processed foods and savory products.
These ribonucleotides are often used in combination with monosodium glutamate (MSG) to enhance the overall flavor profile of foods.

Ribonucleotides are approved food additives in many countries and are commonly used in food products such as soups, sauces, snacks, and ready-to-eat meals.
They contribute to the savory or meaty flavor (umami taste) of foods and help improve taste perception and consumer acceptance.
Ribonucleotides are sometimes included in nutritional supplements and infant formulas to provide additional nucleotide precursors for DNA and RNA synthesis.

These supplements are marketed for their potential benefits in supporting growth, immunity, and gastrointestinal health, particularly in infants and young children.
Ribonucleotides may be used in cosmetics and personal care products for their purported skin conditioning and anti-aging properties.
They are sometimes included in topical formulations, creams, and serums targeting skin rejuvenation and hydration, although scientific evidence supporting their efficacy in skincare is limited.

Ribonucleotides can serve as building blocks for the synthesis of biodegradable polymers with applications in drug delivery, tissue engineering, and sustainable materials.
Polymeric nanoparticles and hydrogels incorporating ribonucleotide-derived monomers offer controlled release properties and biocompatibility for various biomedical and environmental applications.
Ribonucleotides are fundamental building blocks for the synthesis of both RNA and DNA molecules.

While ribonucleotides are used directly in RNA synthesis, they also serve as precursors for deoxyribonucleotides, which are incorporated into DNA during DNA replication and repair processes.
Ribonucleotide analogs, such as ribavirin and sofosbuvir, are used as antiviral agents to treat viral infections.
These analogs interfere with viral RNA synthesis and replication, thereby inhibiting viral replication and reducing viral load in infected individuals.

Radioactively labeled ribonucleotides, such as 18F-fluorodeoxyglucose (18F-FDG), are used as radiopharmaceuticals for positron emission tomography (PET) imaging.
These tracers are used to visualize metabolic activity and glucose uptake in tissues, aiding in the diagnosis and monitoring of various diseases, including cancer.
Ribonucleotides are used in various biochemical assays and enzymatic reactions to study RNA processing, modification, and metabolism.

Techniques such as in vitro transcription, reverse transcription, and RNA labeling rely on ribonucleotides as substrates or cofactors for enzyme-mediated reactions.
Ribonucleotides are employed in the development of RNA-based therapeutics, including RNA vaccines, mRNA therapeutics, and RNAi-based drugs.
These therapies harness the specificity and versatility of RNA molecules to modulate gene expression, trigger immune responses, or target disease-causing genes for degradation.

Ribonucleotides are used in gene editing technologies, such as CRISPR-Cas9 and other programmable nucleases, to introduce specific changes in DNA sequences.
RNA molecules guide the Cas9 enzyme to target DNA sequences, where it induces site-specific double-strand breaks for gene editing or genome engineering purposes.
Ribonucleotides, particularly RNA markers such as ribosomal RNA (rRNA) and messenger RNA (mRNA), are used as indicators of microbial activity and environmental health in water quality monitoring and soil microbiology studies.

Changes in RNA expression profiles can provide insights into microbial community dynamics and ecosystem functioning.
Ribonucleotides are integrated into RNA-based theranostic platforms, which combine therapeutic and diagnostic functions in a single system.
These platforms utilize RNA molecules for targeted drug delivery, imaging, and monitoring of therapeutic responses, offering personalized treatment options for various diseases.

Ribonucleotides are explored in regenerative medicine applications, such as tissue engineering and stem cell therapy.
RNA-based approaches, including mRNA reprogramming and RNA-guided differentiation, hold promise for generating functional tissues and organs for transplantation and regenerative therapies.

Safety Profile:
In the United States, consumption of added 5′-ribonucleotides averages 4 mg per day, compared to 2 g per day of naturally occurring purines.
A review of literature by an FDA committee found no evidence of carcinogenicity, teratogenicity, or adverse effects on reproduction.

In 2004, disodium inosinate was proposed to be removed from the food additive list by Codex Alimentarius Commission.
This change did not go through: it is still present in the 2009 Codex Alimentarius list.

RICE BEAN OIL FATTY ACID
cas no 93165-33-4 Fatty acids, rice bran-oil; RICE BRAN ACID; oryza sativa bran oil fatty acids; rice bran oil fatty acids;
RICE OIL
Rice oil is made from the hulled outer layers of rice.
Rice oil's flavorless and has a high smoke point, which makes it a good go-to oil for most high heat cooking.
The origins of Rice oil - unlike vegetable or canola - are much more transparent.


CAS Number: 68553-81-1
EC Number: 271-397-8
MDL number: MFCD00165774


Rice oil is obtained from the bran of the grain of rice (Oryza sativa) a plant grown in large parts of the world, mainly in tropical and subtropical Asia.
Rice oil content ranges from 10 to 16%.
The refined form of Rice oil is used which has a bright yellow colour and is almost odorless.


Rice oil, also known as rice bran extract, is a cooking oil extracted from rice bran, the outer coating of brown rice that is removed when making white rice.
Rice oil contains about 21 percent saturated, 24 percent monounsaturated, and 37 percent polyunsaturated fats.


For comparison, olive oil contains 13 percent saturated and 74 percent monounsaturated fatty acids.
Rice oil is the oil extracted from the hard outer brown layer of rice (Oryza sativa) after chaff (rice husk).
Rice oil is known for its high smoke point of 232 °C (450 °F) and mild flavor, making it suitable for high-temperature cooking methods such as stir frying and deep frying.


Rice oil is an oil characterized by high levels of tocopherols and tocotrienols, and it has a very high oxidative stability.
Rice oil is slightly oily to the touch, but with a rapid absorption.
Rice oil has excellent compatibility with all skin types and provides stability in cosmetic and pharmaceutical formulations.


Rice oil is made from the hulled outer layers of rice.
Rice oil's flavorless and has a high smoke point, which makes it a good go-to oil for most high heat cooking.
The origins of Rice oil - unlike vegetable or canola - are much more transparent.


As evidenced by its name, Rice oil is derived from rice.
While not nearly as ubiquitous as some other cooking oils, Rice oil is a great option that is both suitable for varying types of cooking.
Rice oil is precisely what it sounds like: oil derived from the ‘bran’ - aka the outer layer - of the grain of rice.


Rice oil is essentially the result of taking something that was previously discarded or possibly used as feed for animals and turning it into a substantial, efficient cooking oil that can rival the more popular options.
Because of the sheer amount of rice exported from countries like India and China, Rice oil is primarily produced in those countries.


Rice oil’s considered a sustainable oil because the rice would be hulled and procured regardless, so utilizing the byproduct to create a versatile cooking oil is obviously a great option.
Rice oil is especially known for its anti-oxidant properties.


Rice oil contains a high level of unsaponifiable components including ferulic acid and vegetable squalene which guard against oxidation and help to maintain the skin’s natural production of oils.
Rice oil is extracted from rice bran, the outer layer of the rice grain.


Rice oil is produced from rice bran and rice germ, the most nutritious components of brown rice.
As a result, Rice oil is high in natural antioxidants including Oryzanol, Phytosterols, and Vitamin E.
Oryzanol is a powerful natural antioxidant found only in Rice oil, not other types of cooking oils.


Rice oil has a unique taste and is rich in nutrients like good fats and antioxidants.
Research shows that cooking with Rice oil is good for your health.
Rice oil is cooking oil made from rice grain husks or bran.


Rice bran is the byproduct of rice polishing or milling.
Rice oil is then processed to produce edible oil.
Rice oil is extracted by distilling it in liquid or mechanical cold pressing.


The Rice oil is a food-grade oil produced from fresh Japanese brown rice bran and germ.
As the ingredients are not genetically modified, Rice oil is safe and secure.
Homemade food is considered the path to nourishment and holistic health.


The key to a healthy home-cooked meal is the right choice of cooking oil.
Rice oil is a vegetable oil and a by-product of rice bran.
Rice oil has been gaining popularity as a premium edible oil in Asian countries like India, China, Japan, Thailand and Taiwan.


This wonder oil, Rice oil, might become a boon for better cooking due to its unique properties like prolonged shelf life, high smoke (burning) point, less greasy and less oily, along with enhancing the flavour of food.
In Japan, Rice oil is called ‘Heart Oil’ whereas, in western countries, it is a ‘Functional Food’ or ‘Health Food’.


Rice oil contains a heart-friendly phytochemical, oryzanol, making it an ideal cooking oil
Let us learn about Rice oil health benefits, properties, side effects and more.
Rice oil may act as an antioxidant.


Rice oil may reduce inflammation.
Rice oil may lower blood glucose levels.
Rice oil may boost immunity.


Rice oil may lower bad cholesterol levels.
Rice oil may be hypoallergenic (unlikely to cause allergic reactions).
Rice oil may reduce blood pressure.


Rice oil is a less refined, low-fat oil extracted from the outer layer of the rice called bran.
Rice oil is extremely light, versatile and delicious.
Use Rice oil to fry, sauté, in salad dressings, baking, dipping oils and where ever you use cooking oil.


Once you use Rice oil you will be amazed cooking light and healthy is also the best tasting.
Rice oil has a smoke point that is between 240 - 255 degrees, which is one of the highest smoke points among the different types of oils.
This is one of the reasons why Rice oil is very versatile; from making a salad dressing to frying the crispiest chips.


The pure Rice oil is extracted from the thin pericarp of the rice grain.
Not only a sustainable product but also a versatile product with health benefits.
Discover Rice oil as the new basic product for your kitchen.


As the word implies, Rice oil is a part of rice.
However, rice oil is not extracted from the rice grain itself, but from the membrane and the germ that is located between the rice grain and the shell.
This is a part of the rice that contains the most nutrients and is also a by-product of the rice plant, which makes this a very sustainable product.


King rice oil contains a correct ratio of different fatty acids, which is a good addition to our daily diet.
Rice oil contains vitamins, minerals and a high content of Oryzanol.
Oryzanol is an antioxidant found only in rice oil.


Oryzanol lowers, among other things, the cholesterol level in the blood.
Rice oil is the oil extracted from the hard outer brown layer of rice called bran.
Rice oil is known for its high smoke point of 232 °C (450 °F) and mild flavor, making it suitable for high-temperature cooking methods such as stir frying and deep frying.


Rice oil is popular as a cooking oil in East Asia, the Indian subcontinent, and Southeast Asia including India, Nepal, Bangladesh, Indonesia, Japan, Southern China and Malaysia.



USES and APPLICATIONS of RICE OIL:
Unrefined Rice oil has a nutty, slightly sweet flavor that can be used for salad dressings and other raw applications.
Rice oil is also popular for high-temperature cooking applications, such as deep-frying and stir-frying, because of its high smoke point and antioxidants.
Rice oil is popular as cooking oil in several Asian countries, including Bangladesh, Japan, India, Korea, Indonesia and China.


Rice oil is also used as an ingredient for salad dressings due to its delicate and light flavour.
This Rice oil is perfect for cooking dishes and cuisines, especially for making fried rice or stir-fried vegetables.
Rice oil is created with a range of well-selected, non-GMO ingredients, produced by a low-temperature physical pressing process, and dewaxed at room temperature.


Rice oil is packed with vitamin E and with zero cholesterol, which is healthy and natural.
Rice oil is softening and moisturising and makes an excellent addition to anti-ageing skin care products.
Rice oilcommonly used as a cooking oil in many Asian countries, including Japan, India, and China.


As a byproduct of rice milling, rice bran is usually used as animal feed or discarded as waste.
Yet, Rice oil has recently gained attention for its potential health benefits as an oil.
Rice oil is extracted from the germ and inner husk of rice.


Rice oil has a mild taste and is popular in Asian cuisine because of its suitability for high-temperature cooking methods such as deep-frying and stir-frying.
Rice oil is said to be the secret of good tempura.


Rice oil is an edible vegetable oil with multiple culinary uses.
Rice oil is popular in cooking because it has a high smoking point. You can use it for high-heat cooking.
Rice oil is commonly used in South and East Asian cuisine for stir-frying and deep frying.


Rice oil has gained popularity because of its mild and nutty flavor, cooking quality, and long shelf life.
Studies also show that Rice oil is rich in nutrients and has several health benefits.
Rice oil is mostly monounsaturated – a tablespoon contains 7 grams of monounsaturated fat, three of saturated fat and five of polyunsaturated fat.


In comparison, a tablespoon of extra virgin olive oil contains 11 grams of monounsaturated fat, two grams of saturated fat and one gram of polyunsaturated fat.
Rice oil also contains components of vitamin E that may benefit health.


Food cooked in Rice oil may be less oily with a better taste and flavour.
Rice oil is used for grilling, sauteing, and marinades.
Rice oil is used as a salad dressing.


Rice oil is used as a cooking oil for deep-frying or stir-frying.
People should consult a qualified doctor before using Rice oil in large quantities.
Rice oil is an edible oil which is used in various forms of food preparation.


Rice oil is also the basis of some vegetable ghee.
Rice bran wax, obtained from Rice oil, is used as a substitute for carnauba wax in cosmetics, confectionery, shoe creams, and polishing compounds.
Isolated γ-oryzanol from Rice oil is available in China as an over-the-counter drug, and in other countries as a dietary supplement.
There is no meaningful evidence supporting Rice oil's efficacy for treating any medical condition



ANY OTHER USES OF RICE OIL?
Rice oil in a bowl:
*For Cooking:
Rice oil is particularly effective in high-heat cooking, given it has a high smoke point.
You can use Rice oil while stir-frying, frying or sautéing.
Rice oil also has a light flavor and clean texture and doesn’t overpower the food.
Rice oil is a popular ingredient in Asian countries and is used as a key ingredient in many Japanese, Thai, Indian, and Chinese cuisines.

*For Making Soap:
Another interesting use of Rice oil is in the soapmaking process.
It is made with a combination of Rice oil and other ingredients, along with organic shea butter and sodium hydroxide.
You also add distilled water.



COMPOSITION AND PROPERTIES OF RICE OIL:
Rice oil has a composition similar to that of peanut oil, with 38% monounsaturated, 37% polyunsaturated, and 25% saturated fatty acids.
A component of Rice oil is the γ-oryzanol, at around 2% of crude oil content.
Thought to be a single compound when initially isolated, γ-oryzanol is now known to be a mixture of steryl and other triterpenyl esters of ferulic acids.
Also present are tocopherols and tocotrienols (two types of vitamin E) and phytosterols.



WHAT IS RICE OIL?
HOW IS RICE OIL GOOD FOR YOU?
Rice oil is an extract derived from the rice husk or the hard outer brown layer of rice.
Now to answer the question:

IS RICE OIL GOOD FOR YOU?
Well, the refining process of the rice husk creates a byproduct, and it has numerous benefits for the beauty and health industry.
Rice oil has a high smoke point (450o F) and is quite suitable for dishes involving high temperatures.

The goodness of Rice oil comes from its components.
Rice oil contains y-oryzanol, a potent antioxidant, and other organic chemical compounds like tocopherols and tocotrienols, which have properties of vitamin E.
Most of the benefits of Rice oil come from these compounds, which is what we will discuss now.



WHAT ARE THE BENEFITS OF RICE OIL?
1. Rice oil Boosts Heart Health
Also known as a heart-friendly oil, Rice oil can lower cholesterol levels – thanks to the optimum levels of oryzanol.
In fact, this antioxidant reduces cholesterol absorption and increases cholesterol elimination.

Rice oil also has the best combination of monounsaturated, polyunsaturated, and saturated fats amongst all vegetable oils.
One Iranian study states that taking Rice oil as part of a healthy diet can cut the risk of cardiovascular disease.
In another interesting study, we find that it is Rice oil, and not fiber, that has more effects on cholesterol reduction.


2. Can Be Beneficial For Diabetics
In one study, Rice oil was found to lower blood sugar levels by as much as 30%.
Certain sources even tout Rice oil as the most nutritious food on the planet.


3. Aids Weight Loss
As it has the ability to lower cholesterol levels, Rice oil may also aid weight loss.
Rice oil is also rich in natural antioxidants (like oryzanol) that boost metabolism and contribute to healthy weight loss.


4. Treats Dark Spots
Using Rice oil topically has its benefits.
Rice oil evens out the skin tone and reduces dark spots.
Rice oil also helps treat the puffiness around eyes.


5. Helps Treat Eczema
The moisturizing properties of Rice oil may help treat dry skin and eczema.
Other dry skin conditions like dermatitis, rosacea, and even rashes could also be treated with Rice oil.


6. Treats Acne
Rice oil contains oleic and linoleic acids in a balanced ratio, and this can help treat acne.
This is because acne-prone skin is usually deficient in linoleic acid.
Rice oil also contains palmitic acid, another essential fatty acid for healthy skin.


7. Helps Delay Aging
This can be attributed to the presence of squalene in Rice oil, which tightens skin and boosts skin health.
As a consequence, Rice oil slows down wrinkle formation and delays skin aging due to its natural moisturizing action.


8. Boosts Hair Growth
Rice oil contains inositol, a carbohydrate compound that prevents dandruff and reduces split ends.
Rice oil also promotes hair health.
Rice oil contains omega-3 and omega-6 fatty acids (though omega-3 is only in small amounts) that help prevent premature graying of hair.



HERE ARE SURPRISINGLY GOOD BENEFITS OF RICE OIL:
*High in Oryzanol
*High in Phytosterols
*Naturally rich in Vitamin E
*Suitable fatty acid profile
*High in monounsaturated fatty acid (MUFA)
*0 gram Trans fat per serving
*High smoke point
*Light in taste and aroma
*No synthetic antioxidant added
*Non-GMO



PURE RICE OIL:
Rice Oil 100% vegetable, without additives
Rice Oil Suitable for vegetarian food
Rice Oil Neutral taste
Rice Oil High smoke point
Rice Oil Rich in vitamin E
Rice Oil Rich in unsaturated fats
Rice Oil Natural Antioxidants



FATTY ACID COMPOSITION OF RICE OIL:
Fatty acid Lipid number Percentage
Myristic acid C14:0 0.6%
Palmitic acid C16:0 21.5%
Stearic acid C18:0 2.9%
Oleic acid (an omega-9 fatty acid) C18:1 38.4%
Linoleic acid (LA, an omega-6 fatty acid) C18:2 34.4%
α-Linolenic acid (ALA, an omega-3 fatty acid) C18:3 2.2%



PHYSICAL PROPERTIES OF CRUDE AND REFINED RICE OIL:
Property Crude rice bran oil Refined oil
Moisture 0.5-1.0% 0.1-0.15%
Density (15 °C) 0.913-0.920 0.913-0.920
Refractive index 1.4672 1.4672
Iodine value 85-100 95-104
Saponification value 187 187
Unsaponifiable matter 4.5-5.5 1.8-2.5
Free fatty acids 5-15% 0.15-0.2%
Oryzanol 2.0 1.5-1.8
Tocopherol 0.15 0.05
Color (tintometer) 20Y+2.8R 10Y+1.0R



HERE ARE 9 IMPRESSIVE BENEFITS OF RICE OIL:
1. Contains beneficial nutrients
Rice oil provides healthy fats and a variety of other nutrients.
One tablespoon (14 ml) packs 120 calories and 14 grams of fat.

Similarly to other nontropical vegetable oils like canola and olive oil, Rice oil contains higher proportions of heart-healthy unsaturated fat than saturated fat.
Rice oil also boasts 29% of the Daily Value (DV) for vitamin E, a fat-soluble vitamin involved in immune function and blood vessel health.
Other compounds in Rice oil, such as tocotrienols, oryzanol, and plant sterols, have been studied for their health benefits


2. May support healthy blood sugar levels
Rice oil may support healthy blood sugar levels by improving insulin resistance, a risk factor for type 2 diabetes.
Insulin lowers blood sugar by transporting sugar into your cells.
Yet, if you develop insulin resistance, your body stops responding to this hormone.

The morning after 19 healthy men ate a single meal containing 3.7 grams of rice bran mixed in oil, their blood sugar levels dropped 15%, compared with those who didn’t eat this ingredient.
Yet, no changes in insulin levels occurred, suggesting that Rice oil may even support healthy blood sugar levels without affecting insulin.
As such, more research is needed.


3. May promote heart health
Rice oil may promote heart health.
In fact, the Japanese government recognizes Rice oil as a health food because of its cholesterol-lowering effects.

In a 4-week study in people with hyperlipidemia, following a low-calorie diet with 2 tablespoons (30 ml) of Rice oil per day led to significantly decreased LDL (bad) cholesterol, as well as reductions in other heart disease risk factors, such as body weight and hip circumference.
Researchers attributed the improvements in cholesterol levels to Rice oil’s plant sterols, which prevent your body from absorbing cholesterol.


4. Has antioxidant and anti-inflammatory effects
Several compounds in Rice oil have antioxidant and anti-inflammatory effects.
One of these compounds is oryzanol, which has been shown to suppress several enzymes that promote inflammation.

In particular, Rice oil may target inflammation in your blood vessels and heart membrane.
If untreated, this inflammation can trigger atherosclerosis — the hardening and narrowing of the arteries, which can lead to heart disease.
In a 4-week study, 59 people with hyperlipidemia took either 2 tablespoons (30 ml) of Rice oil or soybean oil.
Compared with soybean oil, Rice oil significantly increased people’s antioxidant capacity, which may help combat oxidative stress


5. May have anticancer effects
Tocotrienols, a group of antioxidants in rice oil, may have anticancer effects.
Additional test-tube studies reveal that tocotrienols have strong anticancer effects when combined with other anticancer drugs or chemotherapy.


6–8: Other promising benefits
Rice oil has several other emerging benefits.


6. May fight bad breath
Oil pulling is an ancient practice that involves swishing oil around in your mouth like mouthwash to improve oral health.
One study in 30 pregnant women found that oil pulling with Rice oil reduced bad breath.
Researchers speculate that Rice oil’s rich antioxidant content may be responsible.


7. May enhance immune health
Rice oil may improve your immune response, which is your body’s first line of defense against bacteria, viruses, and other disease-causing organisms.


8. May boost skin health
The antioxidants in Rice oil may support skin health.
In a 28-day study, people experienced improvements in forearm skin thickness, roughness, and elasticity after using a gel and cream containing rice extract twice daily.
Despite a lack of research, several moisturizers and other products marketed to those in search of younger-looking skin contain Rice oil.


9. Easy to add to your diet
Rice oil is quite versatile.
Unlike olive and canola oils, Rice oil’s ideal for frying and baking because its subtle taste won’t overpower a dish.
Rice oil has a nutty, earthy flavor similar to that of peanut oil.

Its high smoke point means that Rice oil’s suitable for high-temperature cooking.
Moreover, Rice oil's beneficial compounds, such as oryzanol and tocotrienols, are well preserved when cooked.
Although few products specify production methods, Rice oil processed using solvent extraction rather than cold pressing may boast more beneficial compounds.

You can use Rice oil for stir-fries, soups, dressings, and vinaigrettes.
Rice oil’s also easy to add to hot cereals like oatmeal.
For a unique twist, you can blend Rice oil with other oils, such as olive or canola oils

The bottom line
Rice oil is produced from rice bran, the outer layer of a rice kernel.
Rice oilrising in popularity due to its potential health benefits, such as improved blood sugar control and heart health.
What’s more, Rice oil offers several antioxidants and may provide anti-inflammatory and anticancer effects.
You can find Rice oil in your local grocery store or online.



POTENTIAL HEALTH BENEFITS OF RICE OIL:
Rice oil is a rich source of vitamins and minerals.
Research has found a number of potential health benefits to consuming Rice oil:

*Lower Cholesterol:
For people with high cholesterol, substituting Rice oil for other fats in their diet may improve health outcomes.
Several studies have shown it to be effective in lowering cholesterol.
This effect may be due to the high concentration of Vitamin E in Rice oil.

*Lower Blood Pressure:
Rice oil can help to lower blood pressure, especially when used in combination with antihypertensive medication.
One study reported that a blend of Rice oil and sesame oil resulted in a significant reduction in blood pressure and cholesterol.

*Blood Sugar Management:
In addition to lowering cholesterol and blood pressure, Rice oil can be effective against high blood sugar for people with Type II Diabetes.
In a randomized study, a blend of 80 % Rice oil and 20 % sesame oil showed significant reduction in fasting and postprandial glucose markers (the amount of sugar in your blood after a meal) after 4 weeks.

*Oral Health:
Rice oil may give you better breath when used for oil pulling.
Although the practice of oil pulling is traditionally done using sesame oil, Rice oil was found to be effective in reducing halitosis (bad breath) when used.



RICE OIL IS A GOOD SOURCE OF:
Vitamin E
Vitamin K
Rice oil is also an excellent source of poly- and mono-unsaturated fats (the “good fats”).
Studies have shown that consuming these unsaturated fats can improve blood cholesterol levels, which can decrease your risk of heart disease and type 2 diabetes.



FAT COMPOSITION OF RICE OIL:
SATURATED FATS OF RICE OIL:
Total saturated 25%
Myristic: 0.6%
Palmitic: 21.5%
Stearic: 2.9%



UNSATURATED FATS OF RICE OIL:
Total unsaturated 75%
Monounsaturated 38%
Oleic acid 38%
Polyunsaturated 37%
Omega-3 fatty acids α-Linolenic: 2.2%
Omega-6 fatty acids Linoleic: 34.4%



PROPERTIES OF RICE OIL:
Food energy per 100 g (3.5 oz) 3,700 kJ (880 kcal)
Smoke point 232 °C (450 °F)
Iodine value 99-108
Acid value 1.2
Saponification value 180-190
Unsaponifiable 3-5



NUTRITIONAL VALUE OF RICE OIL:
Rice oil is a pale yellow, odourless, nutty-flavoured oil with a sweet taste.
Rice oil is free from trans-fat and contains antioxidants like γ-oryzanol, tocotrienols, squalene, tocopherols, etc.
The nutrient value of Rice oil is as follows:
Nutrients Value
Energy 884 Kcal
Fats 100 g
Iron 0.07 mg
Vitamin K 24.7 µg
Vitamin E 32.3 mg



PROPERTIES OF RICE OIL:
Rice oil has gained a status as a ‘heart-healthy oil’.
Rice oil has been categorised as healthy edible oil, possibly due to its following health-benefitting properties.



RICE OIL: IS RICE OIL GOOD FOR YOU?
Rice oil is extracted from the outer bran or husk of rice grains.
Because of its high smoke point, it is useful for high-heat cooking and is often used in various cuisines of South and East Asian countries.
In addition to its culinary uses and unique flavor, Rice oil has a range of health benefits that are supported by research.



NUTRITION INFORMATION OF RICE OIL:
Nutrition Information
One tablespoon of Rice oil contains:
Calories: 120
Protein: 0 grams
Fat: 14 grams
Carbohydrates: 0 grams
Fiber: 0 grams
Sugar: 0 grams



WHAT ARE RICE OIL'S BENEFITS?
Rice oil may reduce blood sugar levels, boost heart health, aid weight loss, treat dark spots and acne, and reverse signs of aging.
Rice oil is the premium edible oil in Japan and is known as “heart oil” because it is rich in gamma oryzanol, vitamin E, and phytosterols that exhibit antioxidant and hypocholesterolaemia effects.
GMO free Rice oil may be "The World's Healthiest" edible oil, containing vitamins, antioxidants, nutrients and trans fat free.
It's not just delicate and flavorful, Rice oil may help lower cholesterol, fight diseases, enhance the immune system, fight free radicals and more.



POTENTIAL USES OF RICE OIL FOR DIABETES:
Rice oil may have blood sugar-lowering properties.
Rice oil, combined with sesame oil used as cooking oil, might reduce the pre- and post-meal plasma glucose levels in type 2 diabetic patients.
These anti-diabetic properties of Rice oil might be due to the high amount of γ-oryzanol.

Rice oil might stimulate insulin production in the body and regulate blood glucose levels by activating liver enzymes, lowering blood glucose levels.
However, diabetes is a serious condition; therefore, getting a proper diagnosis and treatment is necessary.
So, kindly do not rely on Rice oil for managing your sugar levels.



POTENTIAL USES OF RICE OIL FOR SKIN:
The skin benefits of Rice oil may be associated with squalene and tocotrienols.
These antioxidants may be similar to the skin’s natural oils, which may be easily absorbed into the skin, retaining its moisture.
Rice oil may also have anti-inflammatory action, which might help skin repair against the harmful effects of UV rays.
Hence, Rice oil might be used in sunscreens, however, take medical consultations and do not self-medicate.



POTENTIAL USE OF RICE OIL AS AN ANTIOXIDANT:
Rice oil may have antioxidant properties due to the phytochemical γ-oryzanol.
Antioxidants may help enhance body immunity and combat various diseases.
These antioxidants may also fight cancer-causing free radicals in the body, thus, reducing cancer risk.

Besides, Rice oil may be effective for weight loss as it contains oleic acid and linoleic acid, which may help lose weight and manage obesity.
In addition, vitamin E of Rice oil may help enhance brain functioning and balance the endocrine hormones.
However, further research is needed to study the antioxidant nature of Rice oil.



OTHER POTENTIAL USES OF RICE OIL:
Rice oil may be used in sports supplements for muscle development and bodybuilding.
However, take proper consultation from a nutritionist before using it.
Do not self-medicate.
The blend of sesame oil and Rice oil might significantly reduce high blood pressure by lowering triglycerides, fats, lipids and bad cholesterol levels.

Though studies show the benefits of Rice oil in various conditions, these are insufficient, and there is a necessity for further studies to develop the true scope of the benefits of Rice oil on human health.
In addition, each person may respond differently to these herbs.
Therefore, it is essential to consult a physician before using Rice oil for any medical condition.



RICE OIL VS. OLIVE OIL: WHAT IS THE DIFFERENCE?
Both Rice oil and olive oil are healthy for you.
But Rice oil has more antioxidant activity than olive oil because of its high vitamin E content.

Also, Rice oil has more polyunsaturated fats, whereas olive oil has more monounsaturated fats.
Compared to olive oil, Rice oil is more versatile and heat-stable.
You can use it for cooking dishes at high temperatures, including deep frying.

Rice oil has a higher smoking point at about 450 degrees Fahrenheit than olive oil, which smokes at about 360 degrees Fahrenheit.
Rice oil's high smoking point prevents unsaturated fats from breaking down, allowing them to retain their nutritional value.
Olive oil can’t withstand high temperatures and breaks down easily, losing its nutritional properties.

Rice oil has a better cooking quality and can be stored for more time than olive oil.
Here’s a breakdown of the nutrients in Rice oil vs. olive oil.

Nutrients in Rice oil:
One tablespoon or 13.6 grams of Rice oil contains:
120 calories
0 grams of protein
13.6 grams of fats
0 grams carbohydrates
0 grams fiber
0 grams sugar
0.01 milligrams of iron
4.39 milligrams of vitamin E
3.36 micrograms of vitamin K
It also contains 5.34 grams of monounsaturated fats and 4.76 grams of polyunsaturated fats.
Rice oil contains gamma oryzanol, a natural antioxidant.

Nutrients in olive oil:
One tablespoon or 14 grams of olive oil has:
124 calories
14 grams of fat
0 grams of protein
0 grams carbohydrates
0 grams fiber
0 grams sugar
0.14 milligrams of calcium
0.078 milligrams of iron
0.28 milligrams of sodium
0.14 milligrams of potassium
2.01 milligrams of vitamin E
8.43 micrograms of vitamin K



HOW TO ADD RICE OIL TO YOUR DIET?
You can easily add Rice oil to your diet. You can use it for sautéing, grilling, stir-frying, pan-frying, and deep-frying food.
Rice oil’s nutty and earthy flavor also lends a unique taste to salads, soups, and marinades.
You can blend it with other oils like olive oil or canola oil.
You can also substitute it for your regular cooking oil to reap its health benefits.



RELISH OF RICE OIL:
As the Rice oil is not only delicious but also smooth and light with almost no order, the original delicate taste of ingredients are preserved in fried dishes.



RESISTANT TO HEATING, RICE OIL:
As the Rice oil has a high smoke point and is stable (it can be stably used under an elevated temperature), it is best suited for high temperature cooking in foods such as Tempura and stir-fries.



WHAT ARE THE HEALTH BENEFITS OF RICE OIL?
Rice oil has the following health benefits:

*Reduces oxidative damage:
Oxidative damage occurs when there is a build-up of harmful molecules called free radicals in your body.
It can cause cell aging and damage and lead to chronic illnesses.

Antioxidants are bioactive compounds that can destroy free radicals and protect your body against oxidative damage.
Rice oil is rich in vitamin E and gamma oryzanol.
Oil made from the husk of red rice is also rich in another antioxidant called beta-carotene.
Studies show that these bioactive molecules hunt free radicals and protect your body.


*Boosts immunity:
Research shows that Rice oil improves immune function in disease conditions.
Rice oil contains immune system-boosting substances like phytosterols, antioxidants like gamma oryzanol, omega fatty acids, phytonutrients, and minerals.
Having food prepared with Rice oil can protect your body against diseases and infections.


*Prevents inflammation and allergies:
Inflammation can cause diseases like heart problems, cancer, and diabetes.
Reports suggest that Rice oil has anti-inflammatory properties due to its potent bioactive compounds, including gamma oryzanol and ferulic acid.
Ferulic acid and gamma oryzanol also have anti-allergic properties. They stop the molecules that trigger inflammatory responses and stimulate immune cells to prevent allergy.


*Slows down cancer growth:
Inflammation and oxidative damage can affect your cells and trigger cancerous growth.
Foods like rice bran have antioxidants and anti-inflammatory properties, which are ideal for cancer prevention.
Ferulic acid, gamma oryzanol, and vitamin E present in Rice oil show strong antioxidant activity against cancer-causing free radicals.
Evidence suggests that these plant nutrients can slow down and prevent the growth of stomach, colon, breast, prostate, and blood cancers.


*Reduces blood sugar levels:
Rice oil can help manage diabetes by regulating certain proteins that affect your blood sugar.
Research has revealed that rice bran extracts decrease the activity of enzymes like alpha-amylase, which increase blood sugar levels.

Rice bran extracts also promote the uptake and storage of sugar by fat cells, reducing blood glucose levels.
These extracts show insulin-like effects.
Rice oil can thus be a functional food for diabetes control.


*Reduces cholesterol and prevents heart problems:
Several studies have reported that the phytosterols, gamma oryzanol, and tocotrienols in Rice oil have cholesterol-reducing effects.
They reduce the absorption of cholesterol in the body.
Consuming gamma oryzanol-rich Rice oil can also help reduce blood pressure and prevent heart disease and cholesterol build-up in blood vessels.


*Protects the liver:
Gamma oryzanol, ferulic acid, and other antioxidant compounds defend the liver against injury and damage caused by alcohol consumption.



HOW IS RICE OIL MADE?
Rice oil is made from rice bran, the coating that is a by-product of polishing white rice.
Rice grains consist of four main parts: the outer, inedible husk; the oily, nutrient-rich bran; the starchy endosperm; and the tiny germ.
Rice bran contains 17 to 23 percent oil by weight.
To make Rice oil, the rice bran is carefully removed from the grain and expeller-pressed to squeeze the oil out of the bran.
The resulting oil is then refined through filtration.



WHAT IS THE SMOKE POINT OF RICE OIL?
Rice oil has a smoke point of 490 degrees Fahrenheit.
If oil gets heated beyond its smoke point, it starts to break down, producing new compounds that may smell or taste off.
Rice oil has a higher smoke point than most other vegetable oils, including peanut oil (450 degrees Fahrenheit), canola oil (400 degrees Fahrenheit), grapeseed oil (390 degrees Fahrenheit), and extra virgin olive oil (325–375 degrees Fahrenheit).



3 WAYS TO COOK WITH RICE OIL:
Rice oil can be used in raw and cooked preparations, but its high smoke point makes it an ideal cooking oil for high-heat preparations.

1. Stir-fry:
Use Rice oil when stir-frying or shallow-frying, techniques that require high heat.
2. Deep-fry:
For deep-frying, try mixing a blend of Rice oil with a more affordable oil, like peanut oil or your favorite vegetable oil.
3. Salad dressing:
High-quality Rice oil can also add a pleasantly nutty flavor to salad dressings.



5 AMAZING BENEFITS OF RICE OIL FOR SKIN AND HAIR :
5 Amazing Benefits Of Rice oil For Skin And Hair Rice oil is used as a dressing in salads.
Rice oil is not only great for cooking but is also widely used as a natural skin care product.
When Rice oil comes to skin and hair care, natural oils can prove to be quite beneficial.
If you wish to have a soft, supple and nourished skin, then natural oils can do wonders as they have their own unique set of skin benefiting properties.

Rice oil is used as a dressing in salads.
Rice oil is not only great for cooking but is also widely used as a natural skin care product.
Rice oil is quite rich in various vitamins, minerals and antioxidants.

For those wondering, rice bran is the outer layer of rice grain.
Rice oil is the oil extracted from the hard outer brown layer of rice called chaff (rice husk).
Here's a list of 5 benefits that Rice oil has to offer.

1. Nourishes Hair:
Rice oil is rich in omega 3 and 6 fatty acids which help nourish the hair.
If you happen to have frizzy hair, then bring Rice oil to your rescue as regular use of this use oil could possibly make your hair thicker and easily manageable.
To reap its benefits, massage your hair using Rice oil before hair wash.
Rice oil will keep your hair follicles healthy.


2. Protects Skin From UV Rays:
The sun could get pretty merciless to your skin.
To prevent damage caused due to sun's UV Rays you can use some Rice oil.
Take 2 drops of Rice oil and gently massage it over your face until it is fully absorbed.
Rice oil will protect your skin from pollution and also act as a natural sun screen.


3. Acts As A Makeup Remover:
The natural antioxidants present in the Rice oil could also help you get rid of excessive makeup, making your skin look supple and soft.
Rice oil is an excellent source of vitamin E which has the tendency to penetrate deep into your skin's layers.


4. Prevents Early Hair Greying:
The antioxidants present in Rice oil not only provide skin nourishment but also help in keeping the skin young.
Rice oil prevents early signs of hair greying.
Use warm Rice oil and massage your hair twice a week.
To make the most of it, add 2-3 drops of Rice oil to your shampoo as well.


5. Prevents Dark Circles:
Aren't you juts fed up of the dark circles that almost always manages to spoil your look for the day?
Rice oil enhances the blood circulation around the eye area and prevents puffy eyes and dark circles.
The high concentration of sterol in Rice oil lightens the under eye skin and prevents dark circles.

So what are you waiting for?
Bring this natural oil, Rice oil, to your rescue and reap all its benefits!



HOW RICE OIL'S MADE:
According to AOCS, Rice oil is acknowledged as an "up and coming" plant oil that’s being incorporated more and more in cooking.
Rice oil itself is derived by mechanical pressing or solvent extraction and then thoroughly refined to rid of any impurities prior to being ready for use.
Rice oil contains monounsaturated fat (47%), polyunsaturated fatty acids (33%) and saturated fatty acids (20%), according to this study.
Rice oil can also be mixed with other oils to raise the smoke point.



RICE OIL SMOKE POINT:
As we noted in this piece, smoke point is defined as "the temperature at which an oil starts to smoke.
Rice oil has a very mild and light flavor, a viscous consistency, and a smoke point of 450°F.
Rice oil holds up well to all forms of heat, making it a fine option for roasting, sauteing, stir-frying, searing, and even deep frying.



WHERE TO BUY RICE OIL:
While Rice oil is by no means the most ubiquitous cooking oil, it can be purchased alongside most other cooking oils at some supermarkets.
Rice oil can also be found at various online retailers.



HOW TO USE RICE OIL:
Rice oil is a flavorless ‘neutral oil’, so if you stumble upon a recipe that calls for a neutral oil, Rice oil is a good choice!
Rice oil can even be an excellent alternative for butter in baked goods, making it a great non-dairy option, since it helps to tenderize and aerate cakes, muffins, cookies, and more.
You can also use Rice oil in salad dressings or to oil a grill grate.



RICE OIL SUBSTITUTES:
If you don’t have Rice oil, you can substitute for canola, vegetable, peanut, or other neutral oils.



RICINOLEAMIDE DEA
RICINOLIC ACID; RICINIC ACID; RICINOLEIC ACID, N° CAS : 141-22-0 / 7431-95-0, Nom INCI : RICINOLEIC ACID, Nom chimique : 9-Octadecenoic acid, 12-hydroxy-, (9Z, 12R)-, N° EINECS/ELINCS : 205-470-2 / -. Ses fonctions (INCI): Agent nettoyant : Aide à garder une surface propre. Emollient : Adoucit et assouplit la peau. Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile). Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation. Noms français : (R-(Z))-12-HYDROXY-9OCTADENOIC ACID; 12-D-HYDROXY-9-CIS-OCTADECENOIC ACID; 12-HYDROXY-CIS-9-OCTADECANOIC ACID ; 9-OCTADECENOIC ACID, 12-HYDROXY, (R-(Z))-; 9-OCTADECENOIC ACID, 12-HYDROXY- (R-(Z))-; ACIDE RICINOLEIQUE; ACIDE RICINOLIQUE; D-12 HYDROXYOLEIC ACID; Noms anglais : RICINIC ACID; RICINOLEIC ACID; RICINOLIC ACID. Utilisation et sources d'émission: Fabrication de résines, fabrication de produits organiques
RICINOLEIC ACID ( ACIDE RICINOLEIQUE; ACIDE RICINOLIQUE )
12-hydroxy-(cis)-9-octadecenoic acid; ácido ricinoleico; Acide ricinoleique ; L'acide Ricinoleique (French); Acide Ricinoleique; Castor Oil Acid; Cis-12-hydroxyoctadec-9-enoic Acid; D-12-hydroxyoleic Acid; Kyselina 12-hydroxy-9-oktadecenova; Kyselina Ricinolova; 12-hydroxy Oleic Acid; Ricinic Acid; Ricinolic Acid; Ricinolsäure CAS NO:141-22-0; 8040-35-5; 17026-54-9; 25607-48-1; 45260-83-1
RICINOLEIC ACID (COFA)
RICINOLETH-40, Nom INCI : RICINOLETH-40, Classification : Composé éthoxylé. Ses fonctions (INCI). Agent nettoyant : Aide à garder une surface propre. Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile). Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
RICINOLETH-40
Riboflavin 5'-phosphate, monosodium salt; FMN Sodium; Riboflavin 5'-(sodium hydrogen phosphate); Riboflavin-5'-natriumphosphat; 5'-fosfato sódico de riboflavina; 5'-phosphate sodique de riboflavine; Flavin Mononucleotide, Sodium CAS NO: 146-17-8 (Base) 130-40-5 (Sodium)
Ribes nigrum
ribes nigrum l. bud cera ; botrycarpum nigrum bud cera;black currant bud wax; grossularia nigra bud cera; ribes cyathiforme bud cera; ribes nigrum var. europaeum bud cera; ribes nigrum var. pauciflorum bud cera;ribes olidum bud cera;ribes pauciflorum bud cera; wax obtained from the bud of black currant, ribes nigrum l., saxifragaceae CAS NO:68606-81-5
Ribes Nigrum Fruit Extract
ribes nigrum fruit extract; botrycarpum nigrum fruit extract; ribes cyathiforme fruit extract; extract obtained from the fruits of the black currant, ribes nigrum l., saxifragaceae; ribes olidum fruit extract CAS NO:68606-81-5
Riboflavin 5'- Fosfat (Vitamin B2)
VITAMIN B2; RIBOFLAVIN, N° CAS : 83-88-5 - Riboflavine (vitamine B2), Nom INCI : RIBOFLAVIN. Nom chimique : Riboflavin. N° EINECS/ELINCS : 201-507-1. Additif alimentaire : E101, Classification : Règlementé. Ses fonctions (INCI). Colorant cosmétique : Colore les cosmétiques et/ou confère une couleur à la peau. Agent d'entretien de la peau : Maintient la peau en bon état. Noms français : 1-DEOXY-1-(3,4-DIHYDRO-7,8-DIMETHYL-2,4-DIOXOBENZO(G)PTERIDIN-10(2H)-YL)-D-RIBITOL 6,7-DIMETHYL-9-D-RIBITYLISOALLOXAZINE 7,8-DIMETHYL-10-(D-RIBO-2,3,4,5-TETRAHYDROXYPENTYL)BENZO(G)PTERIDINE-2,4-(3H-10H)-DIONE 7,8-DIMETHYL-10-(D-RIBO-2,3,4,5-TETRAHYDROXYPENTYL)ISOALLOXAZINE 7,8-DIMETHYL-10-D-RIBITYLISOPLLOXAZINE RIBOFLAVINE RIBOFLAVINEQUINONE Noms anglais : RIBOFLAVIN Utilisation et sources d'émission Vitamine; (−)-Riboflavin (-)-Riboflavin (-)-Riboflavin (Vitamin B2) solution 1217461-14-7 [RN] 1-Deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-D-ribitol 1-Deoxy-1-(4-hydroxy-7,8-dimethyl-2-oxobenzo[g]pteridin-10(2H)-yl)-D-ribitol [ACD/IUPAC Name] 1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-D-ribitol [ACD/IUPAC Name] 1-Desoxy-1-(4-hydroxy-7,8-dimethyl-2-oxobenzo[g]pteridin-10(2H)-yl)-D-ribitol [German] [ACD/IUPAC Name] 1-Désoxy-1-(4-hydroxy-7,8-diméthyl-2-oxobenzo[g]ptéridin-10(2H)-yl)-D-ribitol [French] [ACD/IUPAC Name] 1-Desoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-D-ribitol [German] [ACD/IUPAC Name] 1-Désoxy-1-(7,8-diméthyl-2,4-dioxo-3,4-dihydrobenzo[g]ptéridin-10(2H)-yl)-D-ribitol [French] [ACD/IUPAC Name] 201-507-1 [EINECS] 6,7-dimethyl-9-D-ribitylisoalloxazine 83-88-5 [RN] Beflavin BEFLAVINE D-Ribitol, 1-deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)- [ACD/Index Name] D-Ribitol, 1-deoxy-1-(4-hydroxy-7,8-dimethyl-2-oxobenzo[g]pteridin-10(2H)-yl)- [ACD/Index Name] Flavin BB Hibon Lactoflavin MFCD00005022 [MDL number] riboflavin Riboflavin (B2) Riboflavin for peak identification riboflavina [Spanish] riboflavine riboflavine [French] riboflavinum [Latin] Riboflavinum Russupteridine Yellow III VITAMIN B2 Vitamin G рибофлавин [Russian] ريبوفلافين [Arabic] 6,7-Dimethyl-9-ribitylisoalloxazine 7,8-dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-Benzo[g]pteridine-2,4(3H,10H)-dione Food Yellow 15 San Yellow B 4-hydroxy-7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]-2H,10H-benzo[g]pteridin-2-one 7,8-dimethyl-10-((2S,3S,4R)-2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4(3H,10H)-dione 7,8-Dimethyl-10-(1' d-ribityl)isoalloxazine 7,8-dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4(3H,10H)-dione 7,8-dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine 7,8-dimethyl-10-(d-ribo-2,3,4,5-tetrahydroxypentyl)riboflavinequinone 7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]-2H,3H,4H,10H-benzo[g]pteridine-2,4-dione 7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]benzo[g]pteridine-2,4-dione 7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]benzo[g]pteridine-2,4-quinone 7,8-Dimethyl-10-ribitylisoalloxazine; 97831 [Beilstein]; Aqua-Flave; Bisulase; Dermadram; D-Ribitol, 1-deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo(g)pteridin-10(2H)-yl)-; Fiboflavin; Flavaxin; flavin [Wiki]; Flaxain; Hyflavin; HYRE ;Isoalloxazine, 7,8-dimethyl-10-D-ribityl-; Lactobene; Lactobin A; Lactoflavine; Lactoflavine, zinvit-g; meilun; Ovoflavin; RBF; Ribipca; Ribocrisina; Riboderm; Riboflavin; Lactoflavin; Vitamin B2; Riboflavina; Riboflavine; Lactoflavin, Vitamin B2; Riboflavinequinone; Ribosyn; Ribotone; Ribovel; Vitaflavine; Vitamin B 2; Vitamin- B2; Vitasan B2;核黄素 [Chinese]; Lactoflavine;Vitamine B2
Riboflavine (vitamine B2)
Oryza sativa bran wax; Rice wax; Ricebran wax; Waxes and waxy substances, rice bran; EINECS 232-409-7 CAS NO:8016-60-2
Rice bran wax
ROSA EXTRACT, Extrait de roses, Origine(s) : Végétale. Nom INCI : ROSA EXTRACT. Ses fonctions (INCI). Astringent : Permet de resserrer les pores de la peau. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Agent d'entretien des ongles : Améliore les caractéristiques esthétiques des ongles. Agent d'entretien de la peau : Maintient la peau en bon état
Rice Protein
Rice Protein; cas no: Mixture
Ricinoleic Acid
SYNONYMS 12-hydroxy-(cis)-9-octadecenoic acid; ácido ricinoleico (Spanish); Acide ricinoleique (French);L'acide Ricinoleique (French); Acide Ricinoleique; Castor Oil Acid; Cis-12-hydroxyoctadec-9-enoic Acid; D-12-hydroxyoleic Acid; Kyselina 12-hydroxy-9-oktadecenova; Kyselina Ricinolova; 12-hydroxy Oleic Acid; Ricinic Acid; Ricinolic Acid; Ricinolsäure (German); Cas No: 141-22-0
Ricinus Communis (Castor) Oil
ozonized castor oil; CASTOR OIL; ricinus communis (castor) oil product with ozone; ricini oleum ;Ricinus communis, Euphorbiaceae CAS NO: 8001-79-4
Risperidone
SYNONYMS Risperidal; Risperidone;3-(2-(4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1- piperidinyl)ethyl)-6,7,8,9-tetrahydro-2- methyl-4H-pyrido [1,2-a] pyrimidin-4-one; Apexidone; Risperidona; Risperidonum; Sequinan; cas no:106266-06-2
RİVANOL/ ETHACRİDİNE LACTATE
Ethacridine lactate; ethacridine monolactate monohydrate, acrinol; Rivanol; 7-ethoxyacridine-3,9-diamine 2-hydroxypropanoate; 2-Ethoxy-6,9-diaminoacridine lactate cas no:1837-57-6
ROBAC SAA 30
ROBAC SAA 30 is a type of flame retardant additive, specifically a reactive organophosphorus compound, used in the production of various materials to improve their fire resistance properties.
ROBAC SAA 30 is commonly employed in polymers, plastics, coatings, and textiles to reduce their flammability and enhance their fire safety.
ROBAC SAA 30 chemically bonds to the polymer matrix during the manufacturing process, forming a stable and durable flame-resistant barrier.

CAS Number: 239446-62-9
Molecular Formula: C34H40N4S6
Molecular Weight: 697.0982
EINECS Number: 427-180-7

Carbamodithioic acid, N,N-bis(phenylmethyl)-, compd. with 2,2a(2)-dithiobis[ethanamine] (2:1), 239446-62-9, DTXSID001088861, 2,2'-dithio di(ethylammonium)-bis(dibenzyldithiocarbamate)

This helps to inhibit the ignition, spread, and intensity of flames in case of a fire incident.
The exact composition and formulation of ROBAC SAA 30 may vary depending on the manufacturer and intended application.
ROBAC SAA 30 is typically designed to meet specific fire safety standards and regulatory requirements in different industries and regions.

Overall, ROBAC SAA 30 plays a crucial role in improving the fire safety of various products while maintaining their mechanical and functional properties.
Active secondary accelerator that synergises strongly with AS100 in low nitrosamine systems.
Also synergises strongly with dithiocarbamates and activated dithiocarbamates to give fast vulcanisation at room temperature.

May be regarded as the most active system for low temperature vulcanisation.
ROBAC SAA 30 in latex vulcanisation, and is used in adhesives and coatings.
ROBAC SAA 30, methyl ester is an organic compound that consists of a carbamate group bonded to two thiols.

There are different forms of this compound, such as diethyl-, dimethyl-, and others, each with a different molecular weight and structure .
ROBAC SAA 30, including carbamodithioic acid, can be synthesized from CO2 .
The most straightforward method for accessing carboxylic acids is the direct carboxylation of carbon nucleophiles using CO2, the simplest alternative feedstock, as the electrophilic partner.

High-energy starting materials, including alkenes/allenes/alkynes, aromatic compounds, and organometallic reagents, are commonly used for the fixation of inactive CO2 to construct carboxylic acid derivatives .
ROBAC SAA 30, including carbamodithioic acid, can react with diazomethane to produce methyl esters.
The first step of the mechanism is a simple acid-base reaction to deprotonate the ROBAC SAA 30.

The carboxylate is then the nucleophile of an SN2 reaction with protonated diazomethane to produce the methyl ester with nitrogen gas as a leaving group .
In organic chemistry, a ROBAC SAA 30 is an organic acid that contains a carboxyl group (−C(=O)−OH)[1] attached to an R-group.
The general formula of a carboxylic acid is often written as R−COOH or R−CO2H, sometimes as R−C(O)OH with R referring to an organyl group (e.g., alkyl, alkenyl, aryl), or hydrogen, or other groups.

ROBAC SAA 30 occur widely.
Important examples include the amino acids and fatty acids.
Deprotonation of a carboxylic acid gives a carboxylate anion.

ROBAC SAA 30 include trivalent and pentavalent phosphorus; this article covers only the more common pentavalent phosphorus compounds.
ROBAC SAA 30s are commonly identified by their trivial names.
They often have the suffix -ic acid.

ROBAC SAA 30 also exist; in this system, carboxylic acids have an -oic acid suffix.
For example, butyric acid (CH3CH2CH2CO2H) is butanoic acid by IUPAC guidelines.
For nomenclature of complex molecules containing a ROBAC SAA 30, the carboxyl can be considered position one of the parent chain even if there are other substituents, such as 3-chloropropanoic acid.

Alternately, it can be named as a "carboxy" or "ROBAC SAA 30" substituent on another parent structure, such as 2-carboxyfuran.

The carboxylate anion (R−COO− or R−CO−2) of a ROBAC SAA 30 is usually named with the suffix -ate, in keeping with the general pattern of -ic acid and -ate for a conjugate acid and its conjugate base, respectively.
For example, the conjugate base of acetic acid is acetate.
ROBAC SAA 30, which occurs in bicarbonate buffer systems in nature, is not generally classed as one of the carboxylic acids, despite that it has a moiety that looks like a COOH group.

ROBAC SAA 30 are polar. Because they are both hydrogen-bond acceptors (the carbonyl −C(=O)−) and hydrogen-bond donors (the hydroxyl −OH), they also participate in hydrogen bonding.
Together, the hydroxyl and carbonyl group form the functional group carboxyl.
ROBAC SAA 30 usually exist as dimers in nonpolar media due to their tendency to "self-associate".

Smaller ROBAC SAA 30s are soluble in water, whereas bigger carboxylic acids have limited solubility due to the increasing hydrophobic nature of the alkyl chain.
These longer chain acids tend to be soluble in less-polar solvents such as ethers and alcohols.
Aqueous sodium hydroxide and ROBAC SAA 30, even hydrophobic ones, react to yield water-soluble sodium salts.

For example, enanthic acid has a low solubility in water (0.2 g/L), but its sodium salt is very soluble in water.
ROBAC SAA 30, any of a class of organic compounds in which a carbon (C) atom is bonded to an oxygen (O) atom by a double bond and to a hydroxyl group (―OH) by a single bond.
A fourth bond links the carbon atom to a hydrogen (H) atom or to some other univalent combining group.

The carboxyl (COOH) group is so-named because of the carbonyl group (C=O) and hydroxyl group.
ROBAC SAA 30 occur widely in nature. The fatty acids are components of glycerides, which in turn are components of fat.
ROBAC SAA 30, such as lactic acid (found in sour-milk products) and citric acid (found in citrus fruits), and many keto acids are important metabolic products that exist in most living cells.

Proteins are made up of amino acids, which also contain carboxyl groups.
ROBAC SAA 30 functional group that characterizes the carboxylic acids is unusual in that it is composed of two functional groups: (1) the carboxyl group and (2) of a hydroxyl group bonded to a carbonyl group.
ROBAC SAA 30 is often written in condensed form as –CO2H or –COOH. Other combinations of functional groups were described previously, and significant changes in chemical behavior as a result of group interactions were described (e.g. phenol & aniline).

In this case, the change in chemical and physical properties resulting from the interaction of the hydroxyl and carbonyl group are so profound that the combination is customarily treated as a distinct and different functional group.
ROBAC SAA 30 are organic chemicals derived from phosphoric acids and its derivatives and contain at least one carbon-phosphorus bond.
The pentavalent types of phosphorus-containing compounds are primarily used in industrial and environmental applications.

ROBAC SAA 30 chemistry is the scientific study of the synthesis and properties of organophosphorus compounds, which are organic compounds containing phosphorus.
They are used primarily in pest control as an alternative to chlorinated hydrocarbons that persist in the environment.
Some organophosphorus compounds are highly effective insecticides, although some are extremely toxic to humans, including sarin and VX nerve agents.

ROBAC SAA 30, like nitrogen, is in group 15 of the periodic table, and thus phosphorus compounds and nitrogen compounds have many similar properties.
The definition of organophosphorus compounds is variable, which can lead to confusion.
In industrial and environmental chemistry, an organophosphorus compound need contain only an organic substituent, but need not have a direct phosphorus-carbon (P-C) bond.

Thus a large proportion of pesticides (e.g., malathion), are often included in this class of compounds.
ROBAC SAA 30 can adopt a variety of oxidation states, and it is general to classify organophosphorus compounds based on their being derivatives of phosphorus(V) vs phosphorus(III), which are the predominant classes of compounds.
In a descriptive but only intermittently used nomenclature, ROBAC SAA 30s are identified by their coordination number σ and their valency λ.

In this system, a phosphine is a σ3λ3 compound.
In organic chemistry, ROBAC SAA 30s are a class of organophosphorus compounds with the general structure O=P(OR)3, a central phosphate molecule with alkyl or aromatic substituents.
They can be considered as esters of phosphoric acid.

ROBAC SAA 30 are best known for their use as pesticides.
Like most functional groups, organophosphates occur in a diverse range of forms, with important examples including key biomolecules such as DNA, RNA and ATP, as well as many insecticides, herbicides, nerve agents and flame retardants.
ROBAC SAA 30 have been widely used in various products as flame retardants, plasticizers, and performance additives to engine oil.

The low cost of production and compatibility to diverse polymers made ROBAC SAA 30 to be widely used in industry including textile, furniture, electronics as plasticizers and flame retardants.
ROBAC SAA 30s are added to the final product physically rather than by chemical bond.
Due to this, ROBAC SAA 30 leak into the environment more readily through volatilization, leaching, and abrasion.

ROBAC SAA 30 have been detected in diverse environmental compartments such as air, dust, water, sediment, soil and biota samples at higher frequency and concentration.
The popularity of ROBAC SAA 30 as flame retardants came as a substitution for the highly regulated brominated flame retardants.

Density: 1.243g/cm3
Boiling point: 220.7°C at 760 mmHg
Refractive index: 1.615
Flash point: 87.3°C
Vapour Pressur: 0.112mmHg at 25°C

ROBAC SAA 30 tend to have higher boiling points than water, because of their greater surface areas and their tendency to form stabilized dimers through hydrogen bonds.
For boiling to occur, either the dimer bonds must be broken or the entire dimer arrangement must be vaporized, increasing the enthalpy of vaporization requirements significantly.
ROBAC SAA 30s are Brønsted–Lowry acids because they are proton (H+) donors.

They are the most common type of organic acid.
ROBAC SAA 30s are typically weak acids, meaning that they only partially dissociate into [H3O]+ cations and R−CO−2 anions in neutral aqueous solution.
For example, at room temperature, in a 1-molar solution of acetic acid, only 0.001% of the acid are dissociated (i.e. 10−5 moles out of 1 mol).

Electron-withdrawing substituents, such as -CF3 group, give stronger acids (the pKa of acetic acid is 4.76 whereas trifluoroacetic acid, with a trifluoromethyl substituent, has a pKa of 0.23).
Electron-donating substituents give weaker acids (the pKa of formic acid is 3.75 whereas acetic acid, with a methyl substituent, has a pKa of 4.76)
Deprotonation of ROBAC SAA 30 gives carboxylate anions; these are resonance stabilized, because the negative charge is delocalized over the two oxygen atoms, increasing the stability of the anion.

Each of the carbon–oxygen bonds in the ROBAC SAA 30 has a partial double-bond character.
ROBAC SAA 30's partial positive charge is also weakened by the -1/2 negative charges on the 2 oxygen atoms.
ROBAC SAA 30 have the general structure P(=O)(OR)3 feature P(V).

Such species are of technological importance as flame retardant agents, and plasticizers.
ROBAC SAA 30s are in the technical sense not organophosphorus compounds but esters of phosphoric acid.
Many derivatives are found in nature, such as ROBAC SAA 30.

Phosphate ester are synthesized by alcoholysis of phosphorus oxychloride.
A variety of mixed amido-alkoxo derivatives are known, one medically significant example being the anti-cancer drug cyclophosphamide.
Also derivatives containing the thiophosphoryl group (P=S) include the pesticide malathion.

The organophosphates prepared on the largest scale are the zinc dithiophosphates, as additives for motor oil.
Several million kilograms of this coordination complex are produced annually by the reaction of phosphorus pentasulfide with alcohols.
ROBAC SAA 30 are esters of phosphonic acid and have the general formula RP(=O)(OR')2.

ROBAC SAA 30 have many technical applications, a well-known member being glyphosate, better known as Roundup.
With the formula (HO)2P(O)CH2NHCH2CO2H, this derivative of glycine is one of the most widely used herbicides.
ROBAC SAA 30 are a class of drugs to treat osteoporosis.

The nerve gas agent sarin, containing both C–P and F–P bonds, is a phosphonate.
ROBAC SAA 30 feature two P–C bonds, with the general formula R2P(=O)(OR').
A commercially significant member is the herbicide glufosinate.

Similar to glyphosate mentioned above, it has the structure CH3P(O)(OH)CH2CH2CH(NH2)CO2H.
ROBAC SAA 30 are a class of compounds encompassing a number of distinct but closely related function groups.
These are primarily the esters of phosphoric acid and can be mono‑esters, di‑esters or tri‑esters depending on the number of attached organic groups (abbreviated as 'R' in the image below).

In general man‑made ROBAC SAA 30 are most often triesters, while biological organophosphates are usually mono- or di-esters.
The hydolysis of triesters can form diesters and monoesters.
The bonding in ROBAC SAA 30 has been a matter of prolonged debate; the phosphorus atom is classically hypervalent, as it possesses more bonds than the octet rule should allow.

The focus of debate is usually on the nature of the phosphoryl P=O bond, which displays (in spite of the common depiction) non-classical bonding, with a bond order somewhere between 1 and 2.
Early papers explained the hypervalence in terms of d-orbital hybridisation, with the energy penalty of promoting electrons into the higher energy orbitals being off-set by the stabilisation of additional bonding.
Later advances in computational chemistry showed that d-orbitals played little significant role in bonding.

Current models rely on either negative hyperconjugation, or a more complex arraignment with a dative-type bond from P to O, combined with back-donation from a 2p orbital on the oxygen.
These models agree with the experimental observations of the phosphoryl as being shorter than P-OR bonds[18] and much more polarised.
ROBAC SAA 30 has been argued that a more accurate depiction is dipolar (i.e. (RO)3P+-O-),[19] which is similar to the depiction phosphorus ylides such as methylenetriphenylphosphorane.

However in contrast to ylides, the phosphoryl group is unreactive and organophosphates are poor nucleophiles, despite the high concentration of charge on the phosphoryl oxygen.
The polarisation accounts in part for the higher melting points of phosphates when compared to their corresponding phosphites.
The bonding in penta-coordinate phosphoranes (i.e. P(OR)5) is entirely different and involves three-center four-electron bonds.

Uses:
The alkali metal salt of dithiocarbamate has many applications, for example, potassium dimethyl dithiocarbamate is used in agriculture Fungicide, herbicide and insecticide.
Another application is the use of chemical synthesis.
In addition, the alkali metal salt of dithiocarbamate is also used as a vulcanization accelerator for synthetic rubber.

ROBAC SAA 30s are widely used as insecticides to control pests in agriculture.
They target insects' nervous systems, disrupting neurotransmission and leading to paralysis or death. Examples include malathion, diazinon, and chlorpyrifos.
Certain ROBAC SAA 30s are used as herbicides to control weeds in crop fields and non-agricultural areas.

They inhibit the activity of key enzymes involved in plant growth. Examples include glyphosate (which contains a phosphonate group) and glufosinate.
ROBAC SAA 30 and phosphine derivatives serve as catalysts in various organic synthesis reactions, such as hydrogenation, cross-coupling, and polymerization processes.
ROBAC SAA 30 are used as stabilizers in polymer production to prevent degradation and enhance the longevity of plastics and rubbers.

ROBAC SAA 30 are commonly used as scale inhibitors in water treatment processes to prevent the formation of scale deposits in boilers, cooling towers, and pipelines.
ROBAC SAA 30 act as corrosion inhibitors to protect metal surfaces from corrosion in water-based systems.
ROBAC SAA 30 and phosphates are used in medicinal chemistry for the development of pharmaceuticals, such as antiviral drugs and bone-targeting agents.

Some phosphonate compounds are used as contrast agents in diagnostic imaging techniques like positron emission tomography (PET) scans.
ROBAC SAA 30, such as triphenyl phosphate (TPP), are used as flame retardants in plastics, textiles, and building materials to reduce the flammability and spread of fires.
ROBAC SAA 30 are used as demulsifiers and corrosion inhibitors in the oil and gas industry to improve the efficiency of production processes and protect equipment from degradation.

ROBAC SAA 30-containing compounds are utilized as metalworking fluids to lubricate and cool cutting tools during machining operations, enhancing their performance and extending tool life.
ROBAC SAA 30 are utilized as cleaning agents and degreasers in metalworking industries.
They help to remove oils, greases, and other contaminants from metal surfaces during machining, cleaning, and surface preparation processes.

Certain ROBAC SAA 30 are used in the photography industry as stabilizers and additives in developing solutions and photoresist formulations.
They help to control the rate of chemical reactions and improve image quality.
ROBAC SAA 30 are employed as water softeners in household and industrial water treatment applications.

They sequester calcium and magnesium ions, preventing them from precipitating and forming scale deposits on surfaces and equipment.
ROBAC SAA 30s are incorporated into adhesive and sealant formulations to improve bonding strength, flexibility, and resistance to heat and chemicals.
They help to enhance the performance and durability of bonded joints and seals in various applications.

ROBAC SAA 30-containing compounds are used as additives in membrane separation processes, such as reverse osmosis and nanofiltration, to improve membrane performance, fouling resistance, and separation efficiency.
ROBAC SAA 30 are used as feed additives in animal nutrition to improve digestion, growth, and health. They may serve as sources of essential minerals or provide other nutritional benefits to livestock and poultry.
ROBAC SAA 30 are employed as active ingredients in paint stripping formulations to remove paint, varnish, and other coatings from surfaces.

They help to break down and dissolve paint layers for easy removal.
ROBAC SAA 30-containing compounds are used as disinfectants and biocides in water treatment, sanitation, and agricultural applications to control microbial growth and prevent the spread of pathogens and diseases.
ROBAC SAA 30 serve as key intermediates and building blocks in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals.

They play essential roles in organic synthesis strategies, such as phosphorylation reactions and phosphine-catalyzed transformations.
Cosmetics and Personal Care Products: Some organophosphorus compounds are used as ingredients in cosmetics, skincare products, and personal care formulations. They may serve various functions, such as emulsifiers, moisturizers, and conditioning agents.

Certain ROBAC SAA 30 are used in firefighting foams, particularly in aqueous film-forming foams (AFFFs) and alcohol-resistant aqueous film-forming foams (AR-AFFFs).
These compounds help to create a stable foam blanket that suppresses fires involving flammable liquids such as gasoline, jet fuel, and oil.
ROBAC SAA 30 are approved as food additives, serving various functions such as antioxidants, preservatives, and emulsifiers.

ROBAC SAA 30s are used in food packaging materials to enhance barrier properties, prolong shelf life, and prevent food spoilage.
ROBAC SAA 30 are used in electronics, such as circuit boards and casings, to improve fire resistance and meet safety standards.
Certain organophosphorus compounds are used as dielectric fluids in transformers and capacitors due to their electrical insulating properties.

ROBAC SAA 30-based flame retardants are incorporated into textiles and fabrics to reduce flammability and improve fire resistance, making them suitable for applications in protective clothing, upholstery, and curtains.
ROBAC SAA 30 are used in wood preservation treatments to protect against decay, fungi, and insects.
ROBAC SAA 30 can be applied as coatings, pressure-treated solutions, or incorporated into the wood during manufacturing processes.

ROBAC SAA 30 are used as additives in paints, coatings, and varnishes to enhance fire resistance, adhesion, and durability.
ROBAC SAA 30 are utilized as waterproofing agents in construction materials such as concrete, mortar, and sealants to improve moisture resistance and durability.

ROBAC SAA 30 are used as additives in automotive antifreeze formulations to prevent corrosion and scale buildup in cooling systems.
ROBAC SAA 30 may be added to fuels as lubricity improvers and anti-wear agents to protect engine components and reduce emissions.

Safety Profile:
Many ROBAC SAA 30 exhibit acute and chronic toxicity to humans and animals.
Exposure to these compounds through inhalation, ingestion, or skin contact can lead to a range of adverse health effects, including irritation, respiratory problems, neurological disorders, and organ damage.
ROBAC SAA 30, such as sarin, soman, and VX, are highly toxic nerve agents that disrupt the nervous system's function.

They inhibit the activity of acetylcholinesterase, an enzyme responsible for breaking down the neurotransmitter acetylcholine, leading to overstimulation of nerve cells and potentially fatal effects, such as respiratory failure and convulsions.
ROBAC SAA 30 pesticides used in agriculture can pose risks to farmworkers, consumers, and the environment.
Chronic exposure to ROBAC SAA 30 has been associated with various health problems, including neurological disorders, developmental abnormalities, and reproductive issues.



ROCRYL 400
Clear colorless, easily flowable liquid monomer with a pungent, sweet odor.
Rocryl 400 comprises of a polymerizable methacrylate functional group in one end and a reactive hydroxyl group at the other end.
Rocryl 400 easily dissolves in water and has relatively low volatility.

CAS: 868-77-9
MF: C6H10O3
MW: 130.14
EINECS: 212-782-2

Rocryl 400 copolymerizes readily with a wide variety of monomers, and the added hydroxyl groups improve adhesion to surfaces, incorporate cross-link sites, and impart corrosion, fogging, and abrasion resistance as well as contribute to low odor, color, and volatility.
Rocryl 400 is an enoate ester that is the monomethacryloyl derivative of ethylene glycol.
Rocryl 400 is biocompatible in nature.
Polymeric hydrogel scaffold can be produced by polymerizing Rocryl 400 in water.
Rocryl 400 is an enoate ester that is the monomethacryloyl derivative of ethylene glycol.
Rocryl 400 has a role as a polymerisation monomer and an allergen.

Rocryl 400 is functionally related to an ethylene glycol and a methacrylic acid.
Rocryl 400 is a hydroxyester compound and a resin monomer used in desensitizing dentin.
By applying Rocryl 400 locally to sensitive teeth, sensitive areas in the teeth get sealed and block the dentinal tubules at the dentin surface from stimuli that cause pain.
This prevents excitation of the tooth nerve and relieves pain caused by tooth hypersensitivity.
Rocryl 400 is the organic compound with the chemical formula H2C\dC(CH3)CO2CH2CH2OH.
Rocryl 400 is a colorless viscous liquid that readily polymerizes.
Rocryl 400 is a monomer that is used to make various polymers.

Rocryl 400 Chemical Properties
Melting point: -12 °C
Boiling point: 67 °C3.5 mm Hg(lit.)
Density: 1.073 g/mL at 25 °C(lit.)
Vapor density: 5 (vs air)
Vapor pressure: 0.01 mm Hg ( 25 °C)
Refractive index: n20/D 1.453(lit.)
Fp: 207 °F
Storage temp.: 2-8°C
Solubility: Chloroform, Methanol (Slightly)
Form: Liquid
pka: 13.83±0.10(Predicted)
Color: Clear
Odor: Ester like
Water Solubility: soluble
Sensitive: Air Sensitive
BRN: 1071583
Stability: Unstable - may polymerize in the absence of stabilizer.
May be stabilized with, or contain small amounts of, diethylene glycol monomethacrylate, di(ethylene glycol)dimethacrylate, methacrylic acid.
Incompatible with strong oxidizing agents, free radical initiators, peroxides, steel.
Closed containers may explode if heated due to runaway polymer
InChIKey: WOBHKFSMXKNTIM-UHFFFAOYSA-N
LogP: 0.42 at 25℃
CAS DataBase Reference: 868-77-9(CAS DataBase Reference)
NIST Chemistry Reference: Rocryl 400 (868-77-9)
EPA Substance Registry System: Rocryl 400 (868-77-9)

Rocryl 400 is completely miscible with water and ethanol, but its polymer is practically insoluble in common solvents.
Rocryl 400's viscosity is 0.0701 Pa⋅s at 20°C and 0.005 Pa⋅s at 30°C.
During polymerization, Rocryl 400 shrinks by approximately 6%.

Uses
Rocryl 400 is used for preparation of hydrophilic polymers for biomedical devices.
Rocryl 400 is the methacrylic monomer for use in UV inks, adhesives, lacquers, dental materials, artificial nails, etc.
Rocryl 400 is used in UV-curable inks and coatings.
Rocryl 400 is also used in adhesives, artificial nails, dental materials and lacquers.
In dentistry, Rocryl 400 is one of the main volatile acrylates along with methyl methacrylate.
Further,Rocryl 400 is used as a monomer in the synthesis of polymers for dental prosthetics and for geotechnical grouting in construction work.

Rocryl 400 is mainly used for the modification of resin and coating.
Rocryl 400 can be used for synthetic textile adhesives and medical polymer monomers.
Rocryl 400 used for producing coatings, resin for automotive topcoat and primer.
In the plastics industry, Rocryl 400 can be used to produce acrylic acid esters containing active hydroxyl groups.
In the coatings industry, Rocryl 400 is equipped with epoxy resin, diisocyanate, melamine formaldehyde resin and so on to prepare two component coatings.
In the oil industry, Rocryl 400 is used as an additive for lubricating oil washing.
Rocryl 400 is used as a chemical reagent in analytical chemistry.

Rocryl 400 is mainly used for the modification of resins and coatings.
The resulting resin may contain reactive hydroxyl groups by copolymerization with other acrylic monomers.
Together with melamine formaldehyde (or urea formaldehyde) resin, epoxy resin, etc., for the manufacture of two-component coatings.
Added to the high-grade car paint, can maintain the mirror gloss for a long time.
Rocryl 400 can also be used as an adhesive for synthetic textiles and a medical polymer monomer.

Contact lenses
In 1960, O. Wichterle and D. Lím described its use in synthesis of hydrophilic crosslinked networks, and these results had great importance for manufacture of soft contact lenses. Polyhydroxyethylmethacrylate is hydrophilic: Rocryl 400 is capable of absorbing from 10 to 600% water relative to the dry weight.
Because of this property, Rocryl 400 was one of the first materials to be used in the manufacture of soft contact lenses.

Use in 3D printing
Rocryl 400 lends itself well to applications in 3D printing as it cures quickly at room temperature when exposed to UV light in the presence of photoinitiators.
Rocryl 400 may be used as a monomeric matrix in which 40nm silica particles are suspended for 3D glass printing.
When combined with a suitable blowing agent such as BOC anhydride Rocryl 400 forms a foaming resin which expands when heated.

Other
In electron microscopy, later in light microscopy, Rocryl 400 serves as an embedding medium.
When treated with polyisocyanates, Rocryl 400 makes a crosslinked polymer, an acrylic resin, that is a useful component in some paints.

Synthesis
Rocryl 400 was first synthesized around 1925.
Common methods of synthesis are:

reaction of methacrylic acid with ethylene oxide;
esterification of methacrylic acid with a large excess of ethylene glycol.

Both these methods give also some amount of ethylene glycol dimethacrylate.
During polymerization of Rocryl 400, it works as crosslinking agent.

Preparation Method
1-The addition reaction of methacrylic acid and ethylene oxide in the presence of a catalyst and a polymerization inhibitor generates crude Rocryl 400, which is degassed and fractionated to obtain a finished product.
2-the potassium salt of methacrylic acid is reacted with chloroethanol in the presence of a polymerization inhibitor to produce crude Rocryl 400, which is salted out and refined to obtain a finished product.

Synonyms
2-HYDROXYETHYL METHACRYLATE
868-77-9
Glycol methacrylate
Hydroxyethyl methacrylate
Glycol monomethacrylate
HEMA
Ethylene glycol methacrylate
2-Hydroxyethylmethacrylate
2-(Methacryloyloxy)ethanol
2-hydroxyethyl 2-methylprop-2-enoate
Mhoromer
Methacrylic acid, 2-hydroxyethyl ester
Ethylene glycol monomethacrylate
Monomer MG-1
(hydroxyethyl)methacrylate
2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester
PHEMA
beta-Hydroxyethyl methacrylate
NSC 24180
2-Hydroxyethyl 2-methylacrylate
CHEBI:34288
PEG-MA
12676-48-1
6E1I4IV47V
.beta.-Hydroxyethyl methacrylate
1,2-Ethanediol mono(2-methyl)-2-propenoate
DTXSID7022128
2-Hydroxyethyl methacrylate (HEMA)
MFCD00002863
NSC-24180
Methacrylic Acid 2-Hydroxyethyl Ester
2-Hydroxyethyl Methacrylate (stabilized with MEHQ)
Bisomer HEMA
2-Hydroxyethyl methacrylate,ophthalmic grade
CCRIS 6879
Ethylene glycol, monomethacrylate
HSDB 5442
EINECS 212-782-2
BRN 1071583
Monomethacrylic ether of ethylene glycol
UNII-6E1I4IV47V
PEG-5 methacrylate
hydroxyethylmethacrylate
1,2-Ethanediol mono(2-methylpropenoate)
hydroxyehtyl methacrylate
hydroxylethyl methacrylate
HEMA [INCI]
2-hydroxyetyl methacrylate
Epitope ID:117123
2-hydroxyethylmethylacrylate
EC 212-782-2
2-hydroxylethyl methacrylate
2-hydroxy ethyl methacrylate
2-hydroxyethyl(methacrylate)
SCHEMBL14886
WLN: Q2OVY1&U1
2-methacryloyloxyethyl alcohol
4-02-00-01530 (Beilstein Handbook Reference)
ethyleneglycol monomethacrylate
BIDD:ER0648
DTXCID202128
Methacrylic acid 2-hydroxyethyl
CHEMBL1730239
CHEBI:53709
2-hydroxyethylmethacrylate (hema)
2-Hydroxyethyl methacrylate, 98%
2-Hydroxyethyl 2-methylacrylate #
NSC24180
Tox21_200415
AKOS015899920
CS-W013439
DS-9647
HY-W012723
NCGC00166101-01
NCGC00166101-02
NCGC00257969-01
CAS-868-77-9
2-HYDROXYETHYL METHACRYLATE [HSDB]
2-Hydroxyethyl methacrylate,low acid grade
1,2-Ethanediol, mono(2-methyl)-2-propenyl
2-HYDROXYETHYL METHACRYLATE [WHO-DD]
FT-0628271
M0085
EN300-98188
D70640
2-Hydroxyethyl methacrylate(hema),technical grade
2-Methyl-2-propenoic acid, 2-hydroxyethyl ester
Hydroxyethyl methacrylate(5.9cp(30 degrees c))
A904584
Hydroxyethyl methacrylate(>200cp(25 degrees c))
Q424799
2-Hydroxyethyl Methacrylate, (stabilized with MEHQ)
J-509674
2-Hydroxyethyl Methacrylate, Stabilized with 250 ppm MEHQ
2-Hydroxyethyl methacrylate, embedding medium (for microscopy)
2-Hydroxyethyl methacrylate, >=99%, contains <=50 ppm monomethyl ether hydroquinone as inhibitor
2-Hydroxyethyl methacrylate, contains <=250 ppm monomethyl ether hydroquinone as inhibitor, 97%
ROCRYL 400 HYDROXYETHYL METHACRYLATE (HEMA)
DESCRIPTION:

ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) (also known as glycol methacrylate) is the organic compound with the chemical formula H2C\dC(CH3)CO2CH2CH2OH.
ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) is a colorless viscous liquid that readily polymerizes.
ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) is a monomer that is used to make various polymers.

CAS Number: 868-77-9
EC Number 212-782-2
Molecular Weight: 130.14
Linear Formula: CH2=C(CH3)COOCH2CH2OH


SYNONYM(S) OF ROCRYL 400 HYDROXYETHYL METHACRYLATE (HEMA) :
1,2-Ethanediol mono(2-methylpropenoate), Glycol methacrylate, HEMA,HEMA; hydroxyethylmethacrylate; glycol methacrylate; glycol monomethacrylate; hydroxyethyl methacrylate; ethylene glycol methacrylate; 2-(methacryloyloxy)ethanol,2-hydroxyethyl methacrylate,glycol methacrylate,HEMA,Historesin,hydroxyethyl methacrylate,2-HYDROXYETHYL METHACRYLATE,868-77-9,Glycol methacrylate,Hydroxyethyl methacrylate,HEMA,Glycol monomethacrylate,Ethylene glycol methacrylate,2-Hydroxyethylmethacrylate,2-(Methacryloyloxy)ethanol,2-hydroxyethyl 2-methylprop-2-enoate,Mhoromer,Methacrylic acid, 2-hydroxyethyl ester,Monomer MG-1,Ethylene glycol monomethacrylate,ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) ,beta-Hydroxyethyl methacrylate,NSC 24180,2-Hydroxyethyl methylacrylate,2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester,PHEMA,CCRIS 6879,CHEBI:34288,Ethylene glycol, monomethacrylate,HSDB 5442,12676-48-1,EINECS 212-782-2,UNII-6E1I4IV47V,BRN 1071583,Monomethacrylic ether of ethylene glycol,6E1I4IV47V,DTXSID7022128,PEG-MA,1,2-Ethanediol mono(2-methyl)-2-propenoate,NSC-24180,2-hydroxyethylmethylacrylate,ethyleneglycol monomethacrylate,DTXCID202128,.beta.-Hydroxyethyl methacrylate,2-hydroxyethylmethacrylate (hema),EC 212-782-2,4-02-00-01530 (Beilstein Handbook Reference),NSC24180,2-ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) ,MFCD00002863,MFCD00081879,2-Hydroxyethyl Methacrylate (stabilized with MEHQ),Bisomer HEMA,2-Hydroxyethyl methacrylate,ophthalmic grade,hydroxyethylmethacrylate,1,2-Ethanediol mono(2-methylpropenoate),hydroxyehtyl methacrylate,hydroxylethyl methacrylate,2-hydroxyetyl methacrylate,2-HEMA,Epitope ID:117123,2-hydroxylethyl methacrylate,2-hydroxyethyl(methacrylate),SCHEMBL14886,WLN: Q2OVY1&U1,2-methacryloyloxyethyl alcohol,BIDD:ER0648,CHEMBL1730239,CHEBI:53709,2-Hydroxyethyl methacrylate, 98%,2-Hydroxyethyl 2-methylacrylate #,Tox21_200415,AKOS015899920,Methacrylic,Acid 2-Hydroxyethyl Ester,CS-W013439,DS-9647,HY-W012723,NCGC00166101-01,NCGC00166101-02,NCGC00257969-01,CAS-868-77-9,PD167321,SY279104,2-HYDROXYETHYL METHACRYLATE [HSDB],2-Hydroxyethyl methacrylate,low acid grade,1,2-Ethanediol, mono(2-methyl)-2-propenyl,2-HYDROXYETHYL METHACRYLATE [WHO-DD],M0085,NS00008941,EN300-98188,D70640,2-Hydroxyethyl methacrylate(hema),technical grade,2-Methyl-2-propenoic acid, 2-hydroxyethyl ester,Hydroxyethyl methacrylate(5.9cp(30 degrees c)),2-Propenoic acid, 2-methyl-,2-hydroxiethyl ester,A904584,Hydroxyethyl methacrylate(>200cp(25 degrees c)),Q424799,2-Hydroxyethyl Methacrylate, (stabilized with MEHQ),J-509674,2-Hydroxyethyl Methacrylate, Stabilized with 250 ppm MEHQ,2-Hydroxyethyl methacrylate, embedding medium (for microscopy),InChI=1/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H,2-Hydroxyethyl methacrylate, >=99%, contains <=50 ppm monomethyl ether hydroquinone as inhibitor,2-Hydroxyethyl methacrylate, contains <=250 ppm monomethyl ether hydroquinone as inhibitor, 97%


ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) , Normal Grade, in the form of a colorless, clear liquid, is an industrial solvent that can be used in automotive coatings and primers.
Because of its vinyl double bond, this product can copolymerize with other monomers to produce copolymers with hydroxy groups.


ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) is an enoate ester that is the monomethacryloyl derivative of ethylene glycol.
ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) has a role as a polymerisation monomer and an allergen.
ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) is functionally related to an ethylene glycol and a methacrylic acid.


ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) is a hydroxyester compound and a resin monomer used in desensitizing dentin.
By applying 2-hydroxyethyl methacrylate locally to sensitive teeth, sensitive areas in the teeth get sealed and block the dentinal tubules at the dentin surface from stimuli that cause pain.
This prevents excitation of the tooth nerve and relieves pain caused by tooth hypersensitivity.




ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) is an ester of Methacrylic acid and is used as a raw material component in the synthesis of polymers.
ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) forms a homopolymer and copolymers.
Copolymers of ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) can be prepared with (meth)acrylic acid and its salts, amides, and esters, as well as (meth)acrylates, acrylonitrile, maleic acid esters, vinyl acetate, vinyl chloride, vinylidene chloride, styrene, butadiene, and other monomers.

ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) , easily entering into the reaction of accession with a wide range of organic and inorganic substances, is used for the synthesis of organic low molecular weight substances.



Clear colorless, easily flowable liquid monomer with a pungent, sweet odor.
ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) comprises of a polymerizable methacrylate functional group in one end and a reactive hydroxyl group at the other end.
ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) easily dissolves in water and has relatively low volatility.

ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) copolymerizes readily with a wide variety of monomers, and the added hydroxyl groups improve adhesion to surfaces, incorporate cross-link sites, and impart corrosion, fogging, and abrasion resistance as well as contribute to low odor, color, and volatility.





SYNTHESIS OF ROCRYL 400 HYDROXYETHYL METHACRYLATE (HEMA) :
Hydroxyethylmethacrylate was first synthesized around 1925.
Common methods of synthesis are:[5]
reaction of methacrylic acid with ethylene oxide;
esterification of methacrylic acid with a large excess of ethylene glycol.

Both these methods give also some amount of ethylene glycol dimethacrylate.
During polymerization of hydroxyethylmethacrylate, it works as crosslinking agent.[5]


PROPERTIES OF ROCRYL 400 HYDROXYETHYL METHACRYLATE (HEMA) :
Hydroxyethylmethacrylate is completely miscible with water and ethanol, but its polymer is practically insoluble in common solvents.
Its viscosity is 0.0701 Pa⋅s at 20°C[6] and 0.005 Pa⋅s at 30°C.[3]
During polymerization, it shrinks by approximately 6%.[6]


APPLICATIONS OF ROCRYL 400 HYDROXYETHYL METHACRYLATE (HEMA) :
Contact lenses[edit]
In 1960, O. Wichterle and D. Lím[7] described its use in synthesis of hydrophilic crosslinked networks, and these results had great importance for manufacture of soft contact lenses.

Polyhydroxyethylmethacrylate is hydrophilic: it is capable of absorbing from 10 to 600% water relative to the dry weight.
Because of this property, it was one of the first materials to be used in the manufacture of soft contact lenses.

Use in 3D printing
Hydroxyethylmethacrylate lends itself well to applications in 3D printing as it cures quickly at room temperature when exposed to UV light in the presence of photoinitiators.
It may be used as a monomeric matrix in which 40nm silica particles are suspended for 3D glass printing.[9]
When combined with a suitable blowing agent such as BOC anhydride it forms a foaming resin which expands when heated.[10]

Other
In electron microscopy, later in light microscopy, hydroxyethylmethacrylate serves as an embedding medium.
When treated with polyisocyanates, polyhydroxyethylmethacrylate makes a crosslinked polymer, an acrylic resin, that is a useful component in some paints.


FEATURES & BENEFITS OF ROCRYL 400 HYDROXYETHYL METHACRYLATE (HEMA)
Chemical resistance
Hydraulic stability
Flexibility
Impact resistance
Adhesion
Weatherability


APPLICATIONS AREAS:
ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) is used in the preparation of solid polymers, acrylic dispersions, and polymer solutions, which are used in various industries.

ROCRYL 400 Hydroxyethyl Methacrylate (HEMA) is applied in the production of:
Coating Resins
Automotive coatings
Architectural coatings
Paper coatings
Industrial coatings
Plastics
Hygiene products
Adhesives & Sealants
Textile finishes
Printing inks
Contact lens
Modifiers
Photosensitive materials
Additives for oil production and transportation








CHEMICAL AND PHYSICAL PROPERTIES OF ROCRYL 400 HYDROXYETHYL METHACRYLATE (HEMA) :
Chemical formula C6H10O3
Molar mass 130.143 g•mol−1
Appearance Colourless liquid
Density 1.07 g/cm3
Melting point −99 °C (−146 °F; 174 K)[2]
Boiling point 213 °C (415 °F; 486 K)[2]
Solubility in water miscible
log P 0.50[1]
Vapor pressure 0.08 hPa
Molecular Weight
130.14 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
XLogP3
0.5
Computed by XLogP3 3.0 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
1
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
3
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
4
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
130.062994177 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
130.062994177 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
46.5Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
9
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
118
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
0
Computed by PubChem
Undefined Atom Stereocenter Count
0
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
1
Computed by PubChem
Compound Is Canonicalized
Yes
CAS number 868-77-9
EC index number 607-124-00-X
EC number 212-782-2
Hill Formula C₆H₁₀O₃
Chemical formula CH₂=C(CH₃)COOCH₂CH₂OH
Molar Mass 130.14 g/mol
HS Code 2916 14 00
Assay (GC, area%) ≥ 97.0 % (a/a)
Density (d 20 °C/ 4 °C) 1.069 - 1.072
Identity (IR) passes test
Molecular Weight 130
Appearance Colorless transparent liquid
Odor Aromatic odor
Refractive Index (25℃) 1.451
Boiling Point (℃ 760mmHg) 205
Freezing Point (℃ 760mmHg) -12
Flash Point (℃) 107 (Cleveland open-cup flash test)
Viscosity (CP 25℃) 6.1
Solubility Readily soluble in water
Stability&
Reactivity Polymerize under sunlight and heat
Chemical Properties:
Purity
min. 98.0 %
Acid Value
max. 1.0 %
Water content
max. 0.3 %
Color APHA
max. 30
Physical Properties:
Appearance
colorless
Physical form
Liquid
Odor
Aromatic
Molecular weight
130.14 g/mol
Polymer Tg
Tg 25 °C
Tg
- 6 °C
Density
1.073 g/mL at 25°C
Boiling Point
211 °C
Freezing Point
- 12 °C
Flash point
96 °C
Melting Point
- 60 °C
Viscosity
6.8 (mPa.s) at 20 °C
Vapor Point
0.065 hPa
pH
4 (500 g/l in water)
Alternative names:
1,2-Ethanediol mono(2-methylpropenoate); Glycol methacrylate; HEMA
Application:
2-Hydroxyethyl methacrylate is wide applications for drug delivery
CAS number :
868-77-9
Purity :
97%
Molecular weight :
130.14
Molecular Formula :
C 6 H 10 O 3


SAFETY INFORMATION ABOUT ROCRYL 400 HYDROXYETHYL METHACRYLATE (HEMA) :
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.



ROCRYL 410 HYDROXYPROPYL METHACRYLATE (HPMA)
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA), which is a chemical compound used in various industrial applications, particularly in the production of polymers and resins.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is an ester of methacrylic acid and propylene glycol.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is a clear, colorless liquid with a pungent, sweet odor.

CAS Number: 27813-02-1
Molecular Formula: C7H12O3
Molecular Weight: 144.17
EINECS Number: 248-666-3

2-Hidroksipropil metakrilat, 923-26-2, 2-Hidroksipropilmetakrilat, HPMA, Akrilik HP, beta-Hidroksipropil metakrilat, 25703-79-1, 2-Hidroksipropil 2-metilakrilat, 2-Hidroksipropil 2-metil-2-propenoat, 2-Propenoik asit, 2-metil-, 2-hidroksipropil ester, Propilen glikol monometakrilat, 2-HPMA, METAKRİLİK ASİT, 2-HİDROKSİPROPİL ESTER, ÇEBİ:53440, 2HPMA, metakrilik asit 2-hidroksipropil ester, V9B8S034AW, 2-hidroksi-n-propil metakrilat, 9086-85-5, 2-hidroksi-3-propil metakrilat, DTXSID1029629, .beta.-hidroksipropil metakrilat, DSSTox_CID_5934, EINECS 213-090-3, BRN 1752228, UNII-V9B8S034AW, BLEMER P, 2-hidroksiproil metakrilat, Epitop Kimliği:131322, DSSTox_RID_77971, DSSTox_RID_78619, DSSTox_GSID_25934, DSSTox_GSID_27936, SCHEMBL19017, DTXCID805934, CHEMBL1873783, 1,2-Propandiol, 1-metakrilat, 2-Hidroksipropil 2-metilakrilat #, CBA81302, Tox21_200694, Tox21_201232, Tox21_202531, MFCD00004536, AKOS015899917, CS-W011008, HİDROKSİPROPİL METAKRİLAT [INCI], NCGC00090806-01, NCGC00090806-02, NCGC00090806-03, NCGC00258248-01, NCGC00258784-01, NCGC00260080-01, AS-59279, CAS-923-26-2, CAS-25703-79-1, CAS-27813-02-1, M0512, NS00014926, Hidroksipropil metakrilat, izomer karışımı, D93082, 2-Propenoik asit,2-metil-,2-hidroksipropil ester, W-100292, Q27124054

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) contains low levels of a polymerization inhibitor along with small amounts of methacrylic acid, and propylene oxide.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is used in the manufacture of acrylic polymers for adhesives, inks, and coatings for automotive, appliance and metal applications.
The added hydroxyl groups improve adhesion to surfaces, incorporate cross-link sites, and impart corrosion, fogging, and abrasion resistance.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) by Dow is hydroxypropyl methacrylate.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) provides hydrophilicity, crosslinking sites and improved adhesion to polymer products.
The shelf life of ROCRYL™ 410 is one year.

Provides hydrophilicity, crosslinking sites and improved adhesion to polymer products.
Recommended for automotive, appliance, & metal coatings as well as printing inks.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is mainly used for hot curing acrylic coatings, UV-curable acrylic materials, photosensitive coating, water soluble plating coating, adhesive, textile treatment agent, ester polymer modifier polymer processing and stem acid water reducing agent, etc., has the advantages of indeed can significantly improve product performance characteristics with less usage amount..

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is a hydrophobic hydroxyl-bearing monomer that is particularly useful in the production of vacuum impregnated sealants for cast aluminum compositions and is also widely used in the production of flexible, UV-curable photopolymer printing plates.
Copolymerization of this product with other acrylic monomers can produce acrylic resin containing active hydroxyl groups.
Two-component coatings were prepared with melamine formaldehyde resin diisocyanate epoxy resin, etc.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is also used as an adhesive for synthetic textiles and as an additive to decontamination lubricants.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is used as a crosslinking monomer for the manufacture of solvent-based or emulsion-based acrylate adhesives.
Copolymerization with other acrylic monomers can produce acrylic resins containing active hydroxyl groups for use as medical materials, dental materials, photosensitive imaging materials, etc.

Two-component or thermosetting coatings can be prepared by reacting with diisocyanate, epoxy resin, melamine-formaldehyde resin, etc. for the coating of automobiles, home appliances, and colored metal shells.
Also used as a synthetic textile adhesive to replace stitches.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) can also be used to manufacture natural or synthetic fiber treatment agents, other synthetic resins and ink modifiers.

This is the main component of ROCRIL 410.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is a clear, colorless liquid with a characteristic odor.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is commonly used as a monomer in the production of acrylic and methacrylic polymers, resins, and coatings.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is the commercial name given to the product containing Hydroxypropyl Methacrylate.
The trade name is often used for marketing and identification purposes.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) has several important properties and uses:

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is highly reactive due to the presence of the methacrylate functional group, which allows it to undergo polymerization reactions.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) can be copolymerized with other monomers to produce a wide range of polymers with different properties.
The hydroxyl group in ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) makes it hydrophilic, meaning it has an affinity for water.

This property can be advantageous in applications where water absorption or adhesion is desired.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) can be used as a crosslinking agent in polymerization reactions, where it helps to link polymer chains together, improving the mechanical properties and durability of the resulting polymer.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is often used as an adhesion promoter in coatings and adhesives, where it enhances the bonding between substrates and the polymer matrix.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is commonly used in the formulation of UV-curable resins for coatings, inks, and adhesives.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is reactivity allows for rapid curing under UV light, leading to fast processing times and improved productivity.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) provides hydrophilicity, crosslinking sites and improved adhesion to polymer products.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is a clear colorless, easily flowable liquid monomer with a pungent, sweet odor.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) comprises of a polymerizable methacrylate functional group in one end and a reactive hydroxyl group at the other end.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) easily dissolves in water and has relatively low volatility.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) copolymerizes readily with a wide variety of monomers, and the added hydroxyl groups improve adhesion to surfaces, incorporate cross-link sites, and impart corrosion, fogging, and abrasion resistance, as well as contribute to low odor, color, and volatility.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is commonly used as a monomer in the production of various polymers and copolymers.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) can undergo free radical polymerization, typically initiated by heat, light, or chemical initiators.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) can be copolymerized with other monomers such as methyl methacrylate (MMA), butyl acrylate (BA), or styrene to tailor the properties of the resulting polymer for specific applications.
Due to its hydroxyl group, ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) imparts hydrophilic properties to the polymers it forms.
This makes ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-containing polymers suitable for applications requiring water absorption, moisture resistance, or compatibility with aqueous systems.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) can act as a crosslinking agent in polymerization reactions, leading to the formation of crosslinked networks within the polymer matrix.
Crosslinking improves the mechanical strength, chemical resistance, and thermal stability of the polymer.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is widely used in the formulation of coatings and adhesives due to its ability to improve adhesion to various substrates, including metals, plastics, and ceramics.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-containing coatings exhibit good film-forming properties, adhesion, and durability, making them suitable for applications in automotive coatings, architectural paints, and industrial adhesives.

Melting point: -58°C
Boiling point: 57 °C/0.5 mmHg (lit.)
Density 1.066 g/mL at 25 °C (lit.)
vapor density: >1 (vs air)
vapor pressure: 0.05 mm Hg ( 20 °C)
refractive index: n20/D 1.447(lit.)
Flash point: 206 °F
storage temp.: 2-8°C
solubility: 107g/l
form: Liquid
color: Clear
Specific Gravity: 1.066
PH: 6 (50g/l, H2O, 20℃)
Viscosity: 8.88mm2/s
Water Solubility: Soluble in water.
BRN: 1752228
InChIKey: GNSFRPWPOGYVLO-UHFFFAOYSA-N
LogP: 0.97 at 20℃

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA), also known as hydroxypropyl methacrylate (HPMA), is a clear colorless, easily flowable liquid monomer with a pungent, sweet odor.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) comprises of a polymerizable methacrylate functional group in one end and a reactive hydroxyl group at the other end.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) easily dissolves in water and has relatively low volatility.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) copolymerizes readily with a wide variety of monomers, and the added hydroxyl groups improve adhesion to surfaces, incorporate cross-link sites, and impart corrosion, fogging, and abrasion resistance, as well as contribute to low odor, color, and volatility.
ROCRYL 410 copolymerizes readily with a wide variety of monomers.
The resulting polymer chains bear pendent hydroxyls that impart the following important properties to the polymer products.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) monomer is used in the manufacture of acrylic polyols, caprolactone monomers, printing plates, and finish coatings for motor vehicles, appliances, and metals.
Other end uses of ROCRYL 410 include adhesives, sealants, and binders.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) provides hydrophilicity, crosslinking sites and improved adhesion to polymer products.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-based polymers have been investigated for various biomedical applications, including drug delivery systems, tissue engineering scaffolds, and biomedical coatings.
The hydrophilic nature of ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) polymers allows for the encapsulation and controlled release of drugs, as well as compatibility with biological systems.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is often incorporated into UV-curable formulations for coatings, inks, and adhesives.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-containing UV-curable coatings are used in applications such as wood coatings, electronic coatings, and graphic arts.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) can also be used as a modifier or additive in various polymer formulations to improve specific properties such as flexibility, adhesion, or impact resistance.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is often blended with other monomers or polymers to achieve the desired performance characteristics.

Uses:
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is used for synthetic medical polymer materials, thermosetting coatings and adhesives.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is used for modification of resins and coatings.
Copolymerizes with other monomers to get acrylic resins including the active hydroxyl group,to perform Esterification reaction and crosslinking reaction, synthetic insoluble resin and improved adhesion, can be used as fiber treating agent.

Disposition of coating industry and epoxy resin, diisocyanate and melamino-formaldehyde resin for the production of two component coatings.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is widely used in the production of polyhydroxyacrylic acid for automotive coatings and refinish coatings as well as for industrial coatings.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is non-toxic, non-yellowing and can also be used as a comonomer in styrenic unsaturated polyester, polymethylmethacrylate acrylic and vinyl ester formulations for anchor bolts and chemical bonding.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) can also be blended with other commercial methacrylates and acrylates to produce emulsion polymers, especially fabric coatings and fabric sizing.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is mainly used for hot curing acrylic coatings, UV-curable acrylic materials, photosensitive coating, water soluble plating coating, adhesive, textile treatment agent, ester polymer modifier polymer processing and stem acid water reducing agent, etc., has the advantages of indeed can significantly improve product performance characteristics with less usage amount.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is widely used in the production of polyhydroxyacrylic acid for automotive coatings and refinish coatings as well as for industrial coatings.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is non-toxic, non-yellowing and can also be used as a comonomer in styrenic unsaturated polyester, polymethylmethacrylate acrylic and vinyl ester formulations for anchor bolts and chemical bonding.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) can also be blended with other commercial methacrylates and acrylates to produce emulsion polymers, especially fabric coatings and fabric sizing.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is a hydrophobic hydroxyl-bearing monomer that is particularly useful in the production of vacuum impregnated sealants for cast aluminum compositions and is also widely used in the production of flexible, UV-curable photopolymer printing plates.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) serves as a key monomer in the production of various polymers and copolymers.
These polymers are used in a wide range of applications such as coatings, adhesives, sealants, elastomers, and biomedical materials.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-containing polymers are used in the formulation of coatings and paints for various applications.

These coatings provide excellent adhesion, durability, and weather resistance, making them suitable for automotive coatings, architectural paints, industrial coatings, and specialty coatings.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-based adhesives and sealants offer strong bonding properties and good adhesion to different substrates.
They are used in automotive assembly, construction, packaging, electronics, and aerospace industries for bonding, sealing, and encapsulation applications.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is commonly used in the formulation of UV-curable coatings, inks, and adhesives.
UV-curable systems containing ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) offer rapid curing, high crosslinking density, and excellent adhesion to various substrates.
They are used in printing, packaging, electronics, and wood coatings industries.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-based polymers are utilized in biomedical applications such as drug delivery systems, tissue engineering scaffolds, wound dressings, and medical coatings.
These polymers provide biocompatibility, controlled release properties, and tailored degradation rates, making them suitable for various medical and pharmaceutical applications.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-containing polymers are used in textile finishing applications to impart water repellency, wrinkle resistance, and other functional properties to fabrics.

They are applied as coatings or finishes to enhance the performance and durability of textiles in apparel, home furnishings, and industrial textiles.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-based polymers are used in paper coatings to improve printability, ink adhesion, and water resistance.
These coatings enhance the surface properties of paper products such as packaging materials, labels, and magazines.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is sometimes used in personal care products such as hair styling gels, nail polish, and skin care formulations as a film-forming agent, thickener, or stabilizer.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-based polymers are used in dentistry for various applications, including dental composites, adhesives, and dental prosthetics.
These materials offer excellent mechanical properties, biocompatibility, and esthetics, making them suitable for restorative and cosmetic dental procedures.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is employed in the formulation of photopolymer resins used in stereolithography (SLA) and digital light processing (DLP) 3D printing technologies.
These resins undergo rapid curing upon exposure to UV light, allowing for the precise fabrication of high-resolution 3D printed parts with intricate geometries.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-containing polymers are used for surface modification of materials to improve their surface properties such as hydrophilicity, adhesion, and corrosion resistance.

Surface-modified materials find applications in automotive, aerospace, electronics, and medical device industries.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-based polymers are used as scale inhibitors and dispersants in water treatment applications to prevent scale formation and deposition in industrial water systems. These polymers help maintain the efficiency of boilers, cooling towers, and water distribution systems by controlling scale and corrosion.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-containing polymers are used in textile printing applications as thickeners and rheology modifiers for pigment pastes and printing inks.
These polymers impart viscosity control, shear stability, and excellent printability to textile printing formulations.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-based polymers are utilized in the oil and gas industry as additives in drilling fluids, cementing slurries, and enhanced oil recovery (EOR) processes.

These polymers help improve fluid rheology, viscosity control, and wellbore stability in oilfield operations.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-based polymers are used as electrolytes in lithium-ion batteries and supercapacitors.
These polymers enhance ion conductivity, mechanical strength, and stability of electrode-electrolyte interfaces, leading to improved performance and lifespan of energy storage devices.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-containing polymers are used in membrane separation processes for water purification, desalination, and gas separation.
These polymers are incorporated into membrane materials to improve selectivity, permeability, and fouling resistance, enhancing the efficiency of separation processes.

ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)-based polymers are used in food packaging applications as barrier coatings and adhesives to improve moisture resistance, barrier properties, and shelf-life of packaged food products.
These coatings help protect food products from external contaminants and maintain their freshness and quality.

Safety Profile:
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) is a skin and eye irritant. Direct contact with the skin or eyes can cause irritation, redness, and discomfort. Prolonged or repeated exposure may lead to dermatitis or other skin disorders.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)'s important to wear appropriate personal protective equipment (PPE), such as gloves and goggles, when handling ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) to minimize the risk of irritation.

Inhalation of ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) vapors or mists may cause respiratory irritation and sensitization in some individuals.
Symptoms may include coughing, wheezing, and shortness of breath.
Work in well-ventilated areas or use respiratory protection if necessary to minimize exposure to airborne HPMA particles.

Some individuals may develop allergic reactions upon exposure to ROCRYL 410 Hydroxypropyl Methacrylate (HPMA).
Sensitization can occur through skin contact or inhalation of ROCRYL 410 Hydroxypropyl Methacrylate (HPMA) vapors.
ROCRYL 410 Hydroxypropyl Methacrylate (HPMA)'s important to monitor workers for signs of allergic reactions and provide appropriate medical attention if symptoms occur.


RODINE 31A
RODINE 31A RODINE 31A is specially designed to help in the prevention of the environmental acid attack on metal components without hampering the acidic effect or in some occasions even enhancing the acid effect in the given process or application. The type and concentration of the Acid Inhibitor needed is determined by the type of metal to be protected and the conditions under which the metal is to be treated. Safety Data Sheet Bonderite S-AD RODINE 31A acid inhibitor is packaged 55 gal per inner. The IDH number for this item is 593979. IDH number: 592762 Product name: BONDERITE S-AD 31A known as RODINE 31A Page 1 of 6 1. PRODUCT AND COMPANY IDENTIFICATION Product name: BONDERITE S-AD 31A known as RODINE 31A IDH number: 592762 Product name: BONDERITE S-AD 31A known as RODINE 31A Page 2 of 6 Classification complies with OSHA Hazard Communication Standard (29 CFR 1910.1200) and is consistent with the provisions of the United Nations Globally Harmonized System of Classification and Labeling of Chemicals (GHS). IDH number: 592762 Product name: BONDERITE S-AD 31A known as RODINE 31A Page 3 of 6 Flammable/Explosive limits - upper: Not applicable Autoignition temperature: Not applicable Flammability: Not applicable Evaporation rate: Not determined Solubility in water: Complete Partition coefficient (n-octanol/water): Not determined VOC content: Not applicable Viscosity: 223 cp Decomposition temperature: Not available. IDH number: 592762 Product name: BONDERITE S-AD 31A known as RODINE 31A Eye contact: This product is severely irritating to the eyes and may cause irreversible damage including burns and blindness. IDH number: 592762 Product name: BONDERITE S-AD 31A known as RODINE 31A Page 5 of 6 IDH number: 592762 Product name: BONDERITE S-AD 31A known as RODINE 31A Hcl Acid Inhibitor; Rodine 213 SPL; Rodine 213 SF; Rodine 214; Rodine 103; Rodine 52; Rodine 85; Sulfuric Acid Inhibitor; Rodine 95; Rodine 57; Rodine 130; Sulfamic Acid Inhibitor; RODINE 31A; Rodine 102; Rodine 92B; Citric Acid Inhibitor; RODINE 31A; Phosphoric Acid Inhibitor; HEDP Acid Inhibitor; EDTA Acid Inhibitor; Rodine 2010; Non-Acidic Coil Cleaner; Acid Inhibitor; Rodine 103 NPF; Water Treatment Chemicals; Boiler Treatment Chemicals; Cooling Tower Chemicals; RO Chemicals; Waste Water Treatment Chemicals; Drinking Water Treatment Chemicals; Scale and Corrision Inhibitor; Cleaners and Disfinfectants; Disinfectant and Sanitizer; Biocides; Cleaning Chemical; Degreasing Chemicals; Descaling Chemicals; Fumigation; Metal Treatment Chemicals; Heat Transfer Fluids; Propylene Glycol; Inhibited Propylene Glycol; Mono Ethlene Glycol; Inhibited Ethylene Glycol; Brine Corrosion Inhibitor; PCM & Eutectics; Coolant & Coolant Additives; Performance Chemicals; Acid Corrosion Inhibitor (Rodine); Air Conditioning Chemicals; Dust Suppressant; Fire Retardant; Evaporation Retardant; Laundry Chemicals different types for various applications and their using temperature. For e.g RODINE 31A, RODINE 102 Type etc. BONDERITE S-AD 31A Known as RODINE 31A Features and Benefits Documents and Downloads Features and Benefits BONDERITE S-AD 31A Industrial cleaner - brownish, chloride-free liquid inhibitor for many acids, mixtures of acids and, conditionally, for hydrochloric acid. RODINE 31A is an aliphatic nitrogen corrosion inhibitor containing an acidic blend of complex alkyl pyridines, 1, 3, diethyl thiourea. It protects steel, brass and copper against the attack of phosphoric, sulfuric, sulfamic, acetic oxalic, formic and citric acid, bisulfate solution and mixtures thereof and conditionally for hydrochloric acid. It is a chloride free inhibitor. RODINE 31A is completely effective up to the following maximum temperatures:- RODINE 31A is available in 35kgs (32ltrs approx.) and 220kgs (198ltrs approx.) HDPE jars and barrels. This product should be stored in original containers in cool and dry place, away from sources of heat, flame and direct sunlight. Please refer Technical Data Sheet, Label and MSDS for more details and shelf life. For replenishment of bath with concentrated pickling acid, CHEMTEX'S RODINE 31A should be dosed at the rate of 0.6 to 2.3kgs (0.5 to 2.0ltrs) per 100kgs of concentrated pickling acid. - Speciality Chemical Product Suppliers RODINE 31A Corrosion Inhibitor effectively limits the acid attack on base metals Designed with an acidic blend of complex alkyl pyridines, 1,3, diethyl thiourea, RODINE 31A serves as an aliphatic nitrogen corrosion inhibitor that provides protection to brass, steel and copper against the attack of sulfuric, phosphoric, sulfamic, formic acid, acetic oxalic acid, citric acid, bisulfate solution and mixtures thereof and conditionally for hydrochloric acid. RODINE 31A Corrosion Inhibitor presents itself as a chloride free inhibitor. It is a liquid formulation with a maximum operating temperature of 180 deg F. It imparts excellent pickling and modifies the metal surface to aid in the prevention of corrosion. This acidic corrosion serves as an electro-chemical process which is directed by the diffusion of moisture, oxygen and availability of acidic pollutant on the metal surfaces. This leads to the requirement of acid inhibitors to aid in limiting the acid attack on base metal, thereby helping in to reduce the economic loss in various industrial sectors. The type and concentration of the acid inhibitor used is generally derived by the type and properties of the metal to be protected and the conditions under which the metal is to be treated. RODINE 31A Corrosion Inhibitor is an acid inhibitor specifically protecting metals from corrosion by organic and mineral acid. ChemEqual, being the largest online directory of chemical suppliers, consists of a list of suppliers that deal with trading of RODINE 31A Corrosion Inhibitor or other acid corrosion inhibitor products. Physical State Liquid, Powder Sulfamic Acid Inhibitor, offered, is superlatively utilized for descaling the impact of sulfamic acid over heat transfer surfaces. The product which are included under Sulfamic Acid Inhibitor are RODINE 31A, Rodine 102, Rodine 92B, etc. This formulation is prepared by the addition of superior qualitative corrosion inhibitors and wetting agents for ensuring excellent cleaning of the plate exchangers. It is a powder formulation that RODINE 31A is available with precise pH value for cleaning boilers, paper making, steam generation equipments, cooling water system and heat exchanger systems. RODINE 31A The inhibitor range is extensively recognized for its unique attributes like reduction in metal loss, fume prevention, hydrogen embrittlement reduction, and excellent cleaning. Citric Acid Inhibitor that is RODINE 31A suitably used for preventing the metal surface from the corrosive organic acid like citric acid. The product which are catered under Citric Acid Inhibitor is RODINE 31A. These inhibitors are composed of high quality corrosion inhibitors to provide excellent protection from corrosion. manufactured product RODINE 31A serves as an aliphatic nitrogen corrosion inhibitor containing an acidic blend of complex alkyl pyridines, 1, 3, diethyl thiourea. It protects steel, brass and copper against the attack of phosphoric, sulfuric, sulfamic, acetic oxalic, formic and citric acid, bisulfate solution and mixtures thereof and conditionally for hydrochloric acid. It is a chloride free inhibitor. Citric Acid Inhibitor RODINE 31A processed product- RODINE 31A serves as an aliphatic nitrogen corrosion inhibitor that contains an acidic blend of complex alkyl pyridines, 1, 3, diethyl thiourea. It helps in the protection of steel, brass and copper against the attack of sulfuric, phosphoric, sulfamic, acetic oxalic, formic and citric acid, bisulfate solution and mixtures thereof and conditionally for hydrochloric acid. RODINE 31A It is a chloride free inhibitor. It helps to modify the metal surface to prevent corrosion and imparts excellent pickling. It serves as a single product for multiple acids and is easily soluble with all acid concentrations.Chemtex is an OHSAS 18001, ISO 9001 and ISO 14001 certified company that specializes in the manufacturing of RODINE 31A product. It is also established to be among world's renowned RODINE 31A exporter having its facility in India. Your search for good quality RODINE 31A supplier ends here. RODINE 31A Acid Inhibitor formulated product Rodine 31A has been designed with an acidic blend of complex alkyl pyridines, 1,3, diethyl thiourea. It serves as an aliphatic nitrogen corrosion inhibitor that provides protection to steel, brass, and copper against the attack of phosphoric, sulfuric, sulfamic, acetic oxalic acid, formic acid, citric acid, bisulfate solution and mixtures thereof and conditionally for hydrochloric acid. Rodine 31A presents itself as a chloride free inhibitor. It imparts excellent pickling and modifies the metal surface to aid in the prevention of corrosion. RODINE 31A Sulfamic Acid Corrosion Inhibitor (RODINE 31A, Rodine 102) 1 Ton (Min. Order) sulfamic acid corrosion inhibitor RODINE 31A rodine 102 SPECIFICATIONS RODINE 31A Brand: Bonderite RODINE 31A Trade Name: S-AD Rodine RODINE 31A Series: 31A RODINE 31A Product Type: Acid Inhibitor RODINE 31A Product Form: Liquid RODINE 31A Package Type: Drum RODINE 31A Package Size: 225 KG / 55 gal RODINE 31A Maximum Operating Temperature: +180 °F Storage Condition: Store Between 14°F to 104°F; Store in a Cool, Well-Ventilated Area Package Quantity: 55 gal per inner Bonderite S-AD RODINE 31A acid inhibitor is packaged 55 gal per inner. The IDH number for this item is 593979. product RODINE 31A serves as an aliphatic nitrogen corrosion inhibitor containing an acidic blend of complex alkyl pyridines, 1, 3, diethyl thiourea. It protects steel, brass and copper against the attack of phosphoric, sulfuric, sulfamic, acetic oxalic, formic and citric acid, bisulfate solution and mixtures thereof and conditionally for hydrochloric acid. It is a chloride free inhibitor. Key Features and Benefits Modifies metal surface to prevent corrosion Single product for multiple acids Imparts excellent pickling Chloride free Easily soluble with all acid concentrations RODINE 31A - Corrosion Inhibitor to limit acid attack on base metals Formulated with an acidic blend of complex alkyl pyridines, 1, 3-diethyl thiourea, RODINE 31A serves as an aliphatic nitrogen corrosion inhibitor that provides protection to brass, steel and copper metals against the attack of sulfuric, phosphoric, sulfamic, formic acid, acetic oxalic acid, citric acid, bisulfate solution and mixtures thereof and conditionally for hydrochloric acid solutions. RODINE 31A Corrosion Inhibitor presents itself as a chloride free inhibitor. It has a maximum operating temperature of 180°F. It imparts excellent pickling and modifies the metal surface to help in the prevention of corrosion. Acidic treatment is important in providing protection to the metals used in the industries against scaling and rusting. This acid treatment is mostly carried out variously to assist in the eradication of scale and rust but instead & often triggers abrasion of metals as they exhibit corrosive properties. This process not only influences the metal properties but also causes loss of base metals after acid solution pickling. Acidic Corrosion often causes gradual wearing off of material by acidic compounds. This acidic corrosion is an electrochemical process which is directed by the diffusion of moisture, oxygen and availability of acidic pollutant on the metal surfaces. This brings about the requirement of acid inhibitors to aid in limiting the acid corrosion on base metal, therefore helping reduce the economical loss in several industrial sectors. The type and concentration of the corrosion inhibitor used is generally derived based on the type and properties of the metal to be protected and the conditions under which the metal is to be treated. RODINE 31A Corrosion Inhibitor is an acid inhibitor specifically to protect metals from corrosion by organic and mineral acids Features: -Single product for multiple acids -Helps in imparting excellent pickling -Modifies metal surface to prevent corrosion -Chloride free and is easily soluble with all acid concentrations is the largest online directory of chemical suppliers, consisting of a vast database of manufacturers & suppliers that deal with trading of RODINE 31A Corrosion Inhibitor or other acid corrosion inhibitor products. rodine-31a-corrosion-inhibitor Posted in Corrosion Inhibitor, Uncategorized Tagged ChemEqual chloride free inhibitor Corrosion Inhibitor RODINE 31A Leave a comment Rodine Acid Inhibitor is a series of acid corrosion inhibitors designed to serve worldwide standards for acid inhibitors. They are specially synthesized to provide protection to base metals from acidic corrosion effectively. Rodine Acid Inhibitor products inhibit the corrosion of metals against acids like Hydrochloric, Hydrofluoric, Sulfuric, Phosphoric, Sulfamic, and organic acids blends. The most common products underlined in this range include Rodine 213, Rodine 213 Spl, RODINE 31A, Rodine 103, Rodine 103 NF, Rodine 92B, Rodine 130, and many more. RODINE 31A is specially designed to help in the prevention of the environmental acid attack on metal components without hampering the acidic effect or in some occasions even enhancing the acid effect in the given process or application. The type and concentration of the Acid Inhibitor needed is determined by the type of metal to be protected and the conditions under which the metal is to be treated. Safety Data Sheet Bonderite S-AD RODINE 31A acid inhibitor is packaged 55 gal per inner. The IDH number for this item is 593979. IDH number: 592762 Product name: BONDERITE S-AD 31A known as RODINE 31A Page 1 of 6 1. PRODUCT AND COMPANY IDENTIFICATION Product name: BONDERITE S-AD 31A known as RODINE 31A IDH number: 592762 Product name: BONDERITE S-AD 31A known as RODINE 31A Page 2 of 6 Classification complies with OSHA Hazard Communication Standard (29 CFR 1910.1200) and is consistent with the provisions of the United Nations Globally Harmonized System of Classification and Labeling of Chemicals (GHS). IDH number: 592762 Product name: BONDERITE S-AD 31A known as RODINE 31A Page 3 of 6 Flammable/Explosive limits - upper: Not applicable Autoignition temperature: Not applicable Flammability: Not applicable Evaporation rate: Not determined Solubility in water: Complete Partition coefficient (n-octanol/water): Not determined VOC content: Not applicable Viscosity: 223 cp Decomposition temperature: Not available. IDH number: 592762 Product name: BONDERITE S-AD 31A known as RODINE 31A Eye contact: This product is severely irritating to the eyes and may cause irreversible damage including burns and blindness. IDH number: 592762 Product name: BONDERITE S-AD 31A known as RODINE 31A Page 5 of 6 IDH number: 592762 Product name: BONDERITE S-AD 31A known as RODINE 31A Hcl Acid Inhibitor; Rodine 213 SPL; Rodine 213 SF; Rodine 214; Rodine 103; Rodine 52; Rodine 85; Sulfuric Acid Inhibitor; Rodine 95; Rodine 57; Rodine 130; Sulfamic Acid Inhibitor; RODINE 31A; Rodine 102; Rodine 92B; Citric Acid Inhibitor; RODINE 31A; Phosphoric Acid Inhibitor; HEDP Acid Inhibitor; EDTA Acid Inhibitor; Rodine 2010; Non-Acidic Coil Cleaner; Acid Inhibitor; Rodine 103 NPF; Water Treatment Chemicals; Boiler Treatment Chemicals; Cooling Tower Chemicals; RO Chemicals; Waste Water Treatment Chemicals; Drinking Water Treatment Chemicals; Scale and Corrision Inhibitor; Cleaners and Disfinfectants; Disinfectant and Sanitizer; Biocides; Cleaning Chemical; Degreasing Chemicals; Descaling Chemicals; Fumigation; Metal Treatment Chemicals; Heat Transfer Fluids; Propylene Glycol; Inhibited Propylene Glycol; Mono Ethlene Glycol; Inhibited Ethylene Glycol; Brine Corrosion Inhibitor; PCM & Eutectics; Coolant & Coolant Additives; Performance Chemicals; Acid Corrosion Inhibitor (Rodine); Air Conditioning Chemicals; Dust Suppressant; Fire Retardant; Evaporation Retardant; Laundry Chemicals different types for various applications and their using temperature. For e.g RODINE 31A, RODINE 102 Type etc. BONDERITE S-AD 31A Known as RODINE 31A Features and Benefits Documents and Downloads Features and Benefits BONDERITE S-AD 31A Industrial cleaner - brownish, chloride-free liquid inhibitor for many acids, mixtures of acids and, conditionally, for hydrochloric acid. RODINE 31A is an aliphatic nitrogen corrosion inhibitor containing an acidic blend of complex alkyl pyridines, 1, 3, diethyl thiourea. It protects steel, brass and copper against the attack of phosphoric, sulfuric, sulfamic, acetic oxalic, formic and citric acid, bisulfate solution and mixtures thereof and conditionally for hydrochloric acid. It is a chloride free inhibitor. RODINE 31A is completely effective up to the following maximum temperatures:- RODINE 31A is available in 35kgs (32ltrs approx.) and 220kgs (198ltrs approx.) HDPE jars and barrels. This product should be stored in original containers in cool and dry place, away from sources of heat, flame and direct sunlight. Please refer Technical Data Sheet, Label and MSDS for more details and shelf life. For replenishment of bath with concentrated pickling acid, CHEMTEX'S RODINE 31A should be dosed at the rate of 0.6 to 2.3kgs (0.5 to 2.0ltrs) per 100kgs of concentrated pickling acid. - Speciality Chemical Product Suppliers RODINE 31A Corrosion Inhibitor effectively limits the acid attack on base metals Designed with an acidic blend of complex alkyl pyridines, 1,3, diethyl thiourea, RODINE 31A serves as an aliphatic nitrogen corrosion inhibitor that provides protection to brass, steel and copper against the attack of sulfuric, phosphoric, sulfamic, formic acid, acetic oxalic acid, citric acid, bisulfate solution and mixtures thereof and conditionally for hydrochloric acid. RODINE 31A Corrosion Inhibitor presents itself as a chloride free inhibitor. It is a liquid formulation with a maximum operating temperature of 180 deg F. It imparts excellent pickling and modifies the metal surface to aid in the prevention of corrosion. This acidic corrosion serves as an electro-chemical process which is directed by the diffusion of moisture, oxygen and availability of acidic pollutant on the metal surfaces. This leads to the requirement of acid inhibitors to aid in limiting the acid attack on base metal, thereby helping in to reduce the economic loss in various industrial sectors. The type and concentration of the acid inhibitor used is generally derived by the type and properties of the metal to be protected and the conditions under which the metal is to be treated. RODINE 31A Corrosion Inhibitor is an acid inhibitor specifically protecting metals from corrosion by organic and mineral acid. ChemEqual, being the largest online directory of chemical suppliers, consists of a list of suppliers that deal with trading of RODINE 31A Corrosion Inhibitor or other acid corrosion inhibitor products. Physical State Liquid, Powder Sulfamic Acid Inhibitor, offered, is superlatively utilized for descaling the impact of sulfamic acid over heat transfer surfaces. The product which are included under Sulfamic Acid Inhibitor are RODINE 31A, Rodine 102, Rodine 92B, etc. This formulation is prepared by the addition of superior qualitative corrosion inhibitors and wetting agents for ensuring excellent cleaning of the plate exchangers. It is a powder formulation that RODINE 31A is available with precise pH value for cleaning boilers, paper making, steam generation equipments, cooling water system and heat exchanger systems. RODINE 31A The inhibitor range is extensively recognized for its unique attributes like reduction in metal loss, fume prevention, hydrogen embrittlement reduction, and excellent cleaning. Citric Acid Inhibitor that is RODINE 31A suitably used for preventing the metal surface from the corrosive organic acid like citric acid. The product which are catered under Citric Acid Inhibitor is RODINE 31A. These inhibitors are composed of high quality corrosion inhibitors to provide excellent protection from corrosion. manufactured product RODINE 31A serves as an aliphatic nitrogen corrosion inhibitor containing an acidic blend of complex alkyl pyridines, 1, 3, diethyl thiourea. It protects steel, brass and copper against the attack of phosphoric, sulfuric, sulfamic, acetic oxalic, formic and citric acid, bisulfate solution and mixtures thereof and conditionally for hydrochloric acid. It is a chloride free inhibitor. Citric Acid Inhibitor RODINE 31A processed product- RODINE 31A serves as an aliphatic nitrogen corrosion inhibitor that contains an acidic blend of complex alkyl pyridines, 1, 3, diethyl thiourea. It helps in the protection of steel, brass and copper against the attack of sulfuric, phosphoric, sulfamic, acetic oxalic, formic and citric acid, bisulfate solution and mixtures thereof and conditionally for hydrochloric acid. RODINE 31A It is a chloride free inhibitor. It helps to modify the metal surface to prevent corrosion and imparts excellent pickling. It serves as a single product for multiple acids and is easily soluble with all acid concentrations.Chemtex is an OHSAS 18001, ISO 9001 and ISO 14001 certified company that specializes in the manufacturing of RODINE 31A product. It is also established to be among world's renowned RODINE 31A exporter having its facility in India. Your search for good quality RODINE 31A supplier ends here. RODINE 31A Acid Inhibitor formulated product Rodine 31A has been designed with an acidic blend of complex alkyl pyridines, 1,3, diethyl thiourea. It serves as an aliphatic nitrogen corrosion inhibitor that provides protection to steel, brass, and copper against the attack of phosphoric, sulfuric, sulfamic, acetic oxalic acid, formic acid, citric acid, bisulfate solution and mixtures thereof and conditionally for hydrochloric acid. Rodine 31A presents itself as a chloride free inhibitor. It imparts excellent pickling and modifies the metal surface to aid in the prevention of corrosion. RODINE 31A Sulfamic Acid Corrosion Inhibitor (RODINE 31A, Rodine 102) 1 Ton (Min. Order) sulfamic acid corrosion inhibitor RODINE 31A rodine 102 SPECIFICATIONS RODINE 31A Brand: Bonderite RODINE 31A Trade Name: S-AD Rodine RODINE 31A Series: 31A RODINE 31A Product Type: Acid Inhibitor RODINE 31A Product Form: Liquid RODINE 31A Package Type: Drum RODINE 31A Package Size: 225 KG / 55 gal RODINE 31A Maximum Operating Temperature: +180 °F Storage Condition: Store Between 14°F to 104°F; Store in a Cool, Well-Ventilated Area Package Quantity: 55 gal per inner Bonderite S-AD RODINE 31A acid inhibitor is packaged 55 gal per inner. The IDH number for this item is 593979. product RODINE 31A serves as an aliphatic nitrogen corrosion inhibitor containing an acidic blend of complex alkyl pyridines, 1, 3, diethyl thiourea. It protects steel, brass and copper against the attack of phosphoric, sulfuric, sulfamic, acetic oxalic, formic and citric acid, bisulfate solution and mixtures thereof and conditionally for hydrochloric acid. It is a chloride free inhibitor. Key Features and Benefits Modifies metal surface to prevent corrosion Single product for multiple acids Imparts excellent pickling Chloride free Easily soluble with all acid concentrations RODINE 31A - Corrosion Inhibitor to limit acid attack on base metals Formulated with an acidic blend of complex alkyl pyridines, 1, 3-diethyl thiourea, RODINE 31A serves as an aliphatic nitrogen corrosion inhibitor that provides protection to brass, steel and copper metals against the attack of sulfuric, phosphoric, sulfamic, formic acid, acetic oxalic acid, citric acid, bisulfate solution and mixtures thereof and conditionally for hydrochloric acid solutions. RODINE 31A Corrosion Inhibitor presents itself as a chloride free inhibitor. It has a maximum operating temperature of 180°F. It imparts excellent pickling and modifies the metal surface to help in the prevention of corrosion. Acidic treatment is important in providing protection to the metals used in the industries against scaling and rusting. This acid treatment is mostly carried out variously to assist in the eradication of scale and rust but instead & often triggers abrasion of metals as they exhibit corrosive properties. This process not only influences the metal properties but also causes loss of base metals after acid solution pickling. Acidic Corrosion often causes gradual wearing off of material by acidic compounds. This acidic corrosion is an electrochemical process which is directed by the diffusion of moisture, oxygen and availability of acidic pollutant on the metal surfaces. This brings about the requirement of acid inhibitors to aid in limiting the acid corrosion on base metal, therefore helping reduce the economical loss in several industrial sectors. The type and concentration of the corrosion inhibitor used is generally derived based on the type and properties of the metal to be protected and the conditions under which the metal is to be treated. RODINE 31A Corrosion Inhibitor is an acid inhibitor specifically to protect metals from corrosion by organic and mineral acids Features: -Single product for multiple acids -Helps in imparting excellent pickling -Modifies metal surface to prevent corrosion -Chloride free and is easily soluble with all acid concentrations is the largest online directory of chemical suppliers, consisting of a vast database of manufacturers & suppliers that deal with trading of RODINE 31A Corrosion Inhibitor or other acid corrosion inhibitor products. rodine-31a-corrosion-inhibitor Posted in Corrosion Inhibitor, Uncategorized Tagged ChemEqual chloride free inhibitor Corrosion Inhibitor RODINE 31A Leave a comment Rodine Acid Inhibitor is a series of acid corrosion inhibitors designed to serve worldwide standards for acid inhibitors. They are specially synthesized to provide protection to base metals from acidic corrosion effectively. Rodine Acid Inhibitor products inhibit the corrosion of metals against acids like Hydrochloric, Hydrofluoric, Sulfuric, Phosphoric, Sulfamic, and organic acids blends. The most common products underlined in this range include Rodine 213, Rodine 213 Spl, RODINE 31A, Rodine 103, Rodine 103 NF, Rodine 92B, Rodine 130, and many more.
RONGALITE
Rongalite is a chemical compound with the molecular formula Na+HOCH2SO2−.
Rongalite has many additional names, including Rongalit, sodium hydroxymethylsulfinate, sodium formaldehyde sulfoxylate, and Bruggolite.
Rongalite is listed in the European Cosmetics Directive as sodium oxymethylene sulfoxylate (INCI).

CAS: 6035-47-8
MF: CH7NaO4S
MW: 138.11
EINECS: 611-965-8

Rongalite is water-soluble and generally sold as the dihydrate.
The compound and its derivatives are widely used in the dye industry.
The structure of Rongalite has been confirmed by X-ray crystallography.
The zinc complex Zn(HOCH2SO2)2 is marketed under the trademarks Decroline, Decolin, and Safolin.
Rongalite is an additive in polymers and textiles.
Sodium hydroxymethanesulfinate is called Rongalite C.
Calcium hydroxymethanesulfinate is called Rongalite H.
Rongalite or sodium hydroxymethanesulfinate dihydrate acts as a bleaching agent and it is used in printing and dying industry.
Due to its ability to deliver SO2 dianion, Rongalite is useful to prepare sultines and sulfones.

Rongalite, also called Rongalit (registered trademark of BASF) is sodium hydroxymethylsulfinate, or Na+HOCH2SO2-.
Rongalite has many names, including also sodium formaldehyde sulfoxylate.
Rongalite is water-soluble and generally sold as the dihydrate.
Rongalite was used as industrial bleaching agent and as a reducing agent for vat dying.
The other dominating use today is the application as reducing agent in redox-initiator systems for emulsion polymerization.
One of the typical redox pair examples is t-butyl peroxide.
A niche use is its use as water conditioner for aquaria as Rongalite rapidly reduces chlorine and chloramine and reacts with ammonia to form the innocuous aminomethylsulfinate ion.
Rongalite is also used as an antioxidant in pharmaceutical formulation.

Rongalite is a chemical compound with the molecular formula Na+HOCH2SO2−.
Rongalite has many additional names, including Rongalit, sodium hydroxymethylsulfinate, sodium formaldehyde sulfoxylate, and Bruggolite.
Rongalite is listed in the European Cosmetics Directive as sodium oxymethylene sulfoxylate (INCI).
Oxidation reation of hydroxymethanesulfinic acid with chlorite has been studied in the pH range 4-8.
Rongalite is a sulfur-containing reducing agent.

Rongalite Chemical Properties
Melting point: 64-68 °C(lit.)
Density: 1.8 g/cm3 (20℃)
Vapor pressure: 2.68 hPa (20 °C)
Storage temp.: Store below +30°C.
Solubility alcohol: slightly soluble(lit.)
Form: powder to crystal
Color: White to Almost white
PH: 9.5-10.5 (100g/l, H2O, 20℃)
CAS DataBase Reference: 6035-47-8(CAS DataBase Reference)

Chemical properties translucent white orthorhombic crystal or small pieces.
Apparent density 1.80~1.85g/cm3.
Easily soluble in water, slightly soluble in alcohol.
Rongalite has strong reducibility at high temperature and can make the dyed color disappear, so Rongalite is called hanging white block.
When exposed to acid, Rongalite decomposes at 120 ℃ to produce formaldehyde, hydrogen sulfide and other toxic gases.
The water-free hanging white block is very stable, but Rongalite will gradually decompose in humid air.
The aqueous solution begins to decompose above 60°C, and the dilute solution decomposes much faster than the concentrated solution.
When freshly prepared, Rongalite occurs as white, odorless crystals, which quickly develop a characteristic garlic odor on standing.

Synthesis and reactions
Although available commercially, the salt can be prepared from sodium dithionite and formaldehyde:

Na2S2O4 + 2 CH2O + H2O → HO-CH2-SO3Na + HO-CH2-SO2Na
This reaction proceeds quantitatively, such that dithionite can be determined by its conversion to Rongalite, which is far less O2-sensitive and thus easier to handle.

The hydroxymethanesulfinate ion is unstable in solution towards decomposition to formaldehyde and sulfite.
Addition of at least one equivalent of formaldehyde pushes the equilibrium towards the side of the adduct and reacts further to give the bis-(hydroxymethyl)sulfone.
Such solutions are shelf-stable indefinitely.

Rongalite was originally developed in the early 20th century for the textile industry as a shelf-stable source of sulfoxylate ion, where the latter can be generated at will.
In use, when sodium hydroxymethanesulfinate is made acidic, the reducing sulfoxylate ion and formaldehyde are released in equimolar amounts.
For safety reasons the generation of formaldehyde must be taken into consideration when used industrially.

NaHOCH2SO2 can essentially be considered to be a source of SO22−.
As such Rongalite is used both as a reducing agent and as a reagent to introduce SO2 groups into organic molecules.
Treatment of elemental Se and Te with NaHOCH2SO2 gives solutions containing the corresponding Na2Sex and Na2Tex, where x is approximately 2.
As a nucleophile, NaHOCH2SO2 reacts with alkylating agents to give sulfones.

HO-CH2-SO2Na + 2 C6H5CH2Br → [C6H5CH2]2SO2 + NaBr + CH2O + HBr
Occasionally, alkylation will occur also at oxygen, thus xylylene dibromide gives both the sulfone and the isomeric sulfinate ester.

Use
The original use of Rongalite was as industrial bleaching agent and as a reducing agent for vat dyeing.
Another large-scale use is as a reducing agent in redox-initiator systems for emulsion polymerization.
One of the typical redox pair examples is t-butyl peroxide.
A niche use is its use as water conditioner for aquaria as Rongalite rapidly reduces chlorine and chloramine and reacts with ammonia to form the innocuous aminomethylsulfinate ion.
Rongalite is also used as an antioxidant in pharmaceutical formulation.
Rongalite has been used increasingly in commercial cosmetic hair dye colour removers despite the generation of formaldehyde, a known human carcinogen.
Rongalite has a variety of specialized applications in organic synthesis.
Rongalite used as printing and dyeing agent, styrene butadiene rubber and synthetic resin activator, organic matter decolorization and bleaching agent
Rongalite is a versatile reagent that can be used for a wide range of organic transformations such as:
A SO2-2anion source for the preparation of sulfones and sultines.
Debromination of vicinal dibromoalkanes.
Reductive dehalogenation of aldehydes and ketones.

Pharmaceutical Applications
Rongalite is a water-soluble antioxidant and is generally used as the dihydrate.
Rongalite is used in the formulation of injection products at a level of up to 0.1% w/v in the final preparation administered to the patient.

Production Methods
Rongalite is manufactured from sodium dithionate and formaldehyde in water.

Synonyms
Sodium Hydroxymethanesulfinate Dihydrate
6035-47-8
Sodium formaldehydesulfoxylate dihydrate
Rongalite
Methanesulfinic acid, hydroxy-, monosodium salt, dihydrate
sodium;hydroxymethanesulfinate;dihydrate
Formaldehyde sodium sulfoxylate dihydrate
Monosodium hydroxymethanesulfinate dihydrate
Hydroxymethanesulfinic acid monosodium salt dihydrate
sodium dihydrate hydroxymethanesulfinate
SQ4705447D
sodium formaldehyde sulfoxylate dihydrate
Sodium formaldehyde sulfoxylate [NF]
Sodium formaldehydesulfoxalate
Monosodium hydroxymethanesulfinate
Rongalite dihydrate
NCGC00166400-01
UNII-SQ4705447D
BRUGGOLITE
SodiumHydroxymethanesulfinateDihydrate
MFCD00150598
AKOS022186504
AT30643
sodium hydroxymethane sulfinate dihydrate
NCGC00166400-02
FT-0696356
FORMALDEHYDESULFOXYLATE, MONOSODIUM SALT
EN300-1697657
FORMALDEHYDE SODIUM SULPHOXYLATE DIHYDRATE
SODIUM FORMALDEHYDE SULPHOXYLATE DIHYDRATE
Q27289335
SODIUM FORMALDEHYDE SULFOXYLATE DIHYDRATE [MI]
F8881-2707
Sodium hydroxymethanesulfinate dihydrate, >=98.0% (RT)
Sodium hydroxymethanesulfinate dihydrate(Chunks or pellets)
RONGALITE
DESCRIPTION:
Rongalite is a chemical compound with the molecular formula Na+HOCH2SO2−.
Rongalite has many additional names, including Rongalit, sodium hydroxymethylsulfinate, sodium formaldehyde sulfoxylate, and Bruggolite.
Rongalite is listed in the European Cosmetics Directive as sodium oxymethylene sulfoxylate (INCI).

CAS Number: 149-44-0
EC Number: 205-739-4
IUPAC name: Sodium hydroxymethanesulfinate

CHEMICAL AND PHYSICAL PROPERTIES OF RONGALITE:
Chemical formula: CH3NaO3S
Molar mass: 118.10 g/mol
154.14 g/mol, dihydrate
Appearance: colorless crystals
Density: 1.75 g/cm3, dihydrate
Melting point: 64.5 °C (148.1 °F; 337.6 K) dihydrate
Solubility in water: 600 g/L, dihydrate (approximate)
Acidity (pKa): decomposes at low pH
Molecular Weight 119.10
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 1
Exact Mass 118.97788444
Monoisotopic Mass 118.97788444
Topological Polar Surface Area 76.7 Ų
Heavy Atom Count 6
Formal Charge 1
Complexity 42.2
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes
Appearance (Colour): White
Appearance (Form): Chips
Assay (Iodometric): min. 95.0%
Assay as SO2 (on dried basis): 45.5% to 55.5%
pH (2% aq. solution): 9.5 - 10.5
Loss on drying: max. 27.0%
Sodium sulphite (as Na2SO3) (on dried basis): max. 5.0%
Chemical Name:
Sodium formaldehydesulfoxylate dihydrate; Rongalite; Sodium hydroxymethanesulfinate
Commercial Name: Rongalite
Molecular Weight: 154.12
Specific Gravity: 1.8
Melting Point: 64°C
Appearance: White powder or white lump
Heat of Fusion: 54.84 KJ/mol( 13.2Kcal/mol)
Hygroscopic Point: Relative Humidity 60%
Stable Pour-Point: 50°C max
Solution: clear or sight turbid
M.F: NaHSO2.CH2O.2H2O
Content of NaHSO2•CH2O % :≥ 98.0
State of solubleness: Water solution clear or microturbid
Sulphide: No presence of black color is allowed
Smell: No smell or a little smell of leek

Rongalite is water-soluble and generally sold as the dihydrate.
Rongalite and its derivatives are widely used in the dye industry.
The structure of Rongalite has been confirmed by X-ray crystallography.

Rongalite called sodium hydroxymethanesulfinate with chemical formula CH3NaO3S is a colorless crystalline state.
The trade name registered by BASF is Rongalit.
Generally Rongalite is water soluble and dihydrate.

SYNTHESIS AND REACTIONS OF RONGALITE:
Although available commercially, the salt can be prepared from sodium dithionite and formaldehyde:
Na2S2O4 + 2 CH2O + H2O → HO-CH2-SO3Na + HO-CH2-SO2Na
This reaction proceeds quantitatively, such that dithionite can be determined by its conversion to Rongalite, which is far less O2-sensitive and thus easier to handle.

The hydroxymethanesulfinate ion is unstable in solution towards decomposition to formaldehyde and sulfite.
Addition of at least one equivalent of formaldehyde pushes the equilibrium towards the side of the adduct and reacts further to give the bis-(hydroxymethyl)sulfone.
Such solutions are shelf-stable indefinitely.

Sodium hydroxymethanesulfinate was originally developed in the early 20th century for the textile industry as a shelf-stable source of sulfoxylate ion, where the latter can be generated at will.
In use, when sodium hydroxymethanesulfinate is made acidic, the reducing sulfoxylate ion and formaldehyde are released in equimolar amounts.
For safety reasons the generation of formaldehyde must be taken into consideration when used industrially.

NaHOCH2SO2 can essentially be considered to be a source of SO22−.
As such it is used both as a reducing agent and as a reagent to introduce SO2 groups into organic molecules.
Treatment of elemental Se and Te with NaHOCH2SO2 gives solutions containing the corresponding Na2Sex and Na2Tex, where x is approximately 2.
As a nucleophile, NaHOCH2SO2 reacts with alkylating agents to give sulfones.

HO-CH2-SO2Na + 2 C6H5CH2Br → [C6H5CH2]2SO2 + NaBr + CH2O + HBr
Occasionally, alkylation will occur also at oxygen, thus xylylene dibromide gives both the sulfone and the isomeric sulfinate ester.

Production and Reactions:
Interaction with caustic soda can produce white printing paste.
Suitable conditions and additives can be prepared by sodium dithionite and formaldehyde.
Na2S2O4 + 2 CH2O + H2O NaHOCH2SO3 + NaHOCH2SO2
It can be used as reducing agent thanks to the elements it contains.
NaHOCH2SO2 + 2 C6H5CH2Br [C6H5CH2] 2SO2 + NaBr + CH2O + HBr

USES OF RONGALITE:
The original use of Rongalite was as industrial bleaching agent and as a reducing agent for vat dyeing.
Another large-scale use is as a reducing agent in redox-initiator systems for emulsion polymerization.

One of the typical redox pair examples is t-butyl peroxide.
A niche use is its use as water conditioner for aquaria as it rapidly reduces chlorine and chloramine and reacts with ammonia to form the innocuous aminomethylsulfinate ion.
Rongalite is also used as an antioxidant in pharmaceutical formulation.

Rongalite has been used increasingly in commercial cosmetic hair dye colour removers despite the generation of formaldehyde, a known human carcinogen.
Rongalite has a variety of specialized applications in organic synthesis.

Textile:
In the weaving and knitting sector, Rongalite is mainly used as cellulosic printing and industrial bleach.

Paint:
Rongalite is used as an auxiliary component in boat painting materials.

Chemistry:
In the chemical industry, the redox initiator is also used as an oxidant in pharmaceutical reactions.

Water:
With the mixture formed by reacting with ammonia in appropriate conditions, water treatment is used especially in aquarium cleaning.

Cosmetic:
The interaction with formaldehyde is preferably used in hair dye removal processes


Rongalite is mainly used as a discharging agent, color-discharging agent, reductant in printing and dyeing industry, as an activating agent for production styrene-butadise rubber and synthetic resin, also be used to decolourize and bleach some organic matters, for example: as a bleaching agent in synthetic rubber, sugar-making, and food industries.
Rongalite may be substituted for the sodium hydrosulfite in some special conditions.


SAFETY INFORMATION ABOUT RONGALITE:

First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.




SYNONYMS OF RONGALITE:
MeSH Entry Terms
formaldehydesulfoxylate
formaldehydesulfoxylate dihydrate
formaldehydesulfoxylate, magnesium (2:1) salt
formaldehydesulfoxylate, monosodium salt
Rongalite
sodium formaldehydesulfoxylate
sodium hydroxymethanesulfinate

Depositor-Supplied Synonyms:
sodium;hydroxymethanesulfinic acid
Aldanil
Formapon
Formopan
Hydrolit
Rongalite
Rongalit C
Rongalite C
WLN: Q1SQO &-NA-
Sodium methanalsulfoxylate
Methanesulfinic acid, monosodium salt
Formaldehyde sodium sulfoxylate
Sodium sulfoxylate formaldehyde
Sodium (hydroxymethyl)sulfinate
Formaldehydesulfoxylic acid, sodium salt
Hydroxymethanesulfinic acid, sodium salt
NSC-4847
NSC4847
NSC78331
NSC-78331


RONGALITE
Rongalite is a chemical compound with the molecular formula Na+HOCH2SO2−.
Rongalite called sodium hydroxymethanesulfinate with chemical formula CH3NaO3S is a colorless crystalline state.
Rongalite, also called Rongalit, is sodium hydroxymethylsulfinate, or Na+HOCH2SO2−.


CAS Number: 149-44-0, 6035-47-8 (dihydrate)
EC Number: 205-739-4
MDL number: MFCD00150599
Chemical formula: CH3NaO3S


Rongalite has many names, including also sodium formaldehyde sulfoxylate, and Bruggolite.
Rongalite is listed in the European Cosmetics Directive as sodium oxymethylene sulfoxylate (INCI).
Rongalite is an organic reductant that is stable in alkaline environments.


Rongalite Hydrate is the hydrated version of Sodium Hydroxymethanesulfinate (S634950), which is an organic reductant that is stable in alkaline enviroments but readily decomposes in acidic medium to produce a number of products, one of them being sulfur dioxide.
This salt, Rongalite, has many additional names, including Rongalit, sodium hydroxymethylsulfinate, sodium formaldehyde sulfoxylate, and Bruggolite.


Rongalite is listed in the European Cosmetics Directive as sodium oxymethylene sulfoxylate (INCI).
Rongalite is water-soluble and generally sold as the dihydrate.
The structure of Rongalite has been confirmed by X-ray crystallography.
Generally, Rongalite is water soluble and dihydrate.


Rongalite is a chemical compound with the molecular formula Na+HOCH2SO2−.
Rongalite This salt has many additional names, including Rongalit, sodium hydroxymethylsulfinate, sodium formaldehyde sulfoxylate, and Bruggolite.
Rongalite is listed in the European Cosmetics Directive as sodium oxymethylene sulfoxylate (INCI).
Rongalite is water-soluble and generally sold as the dihydrate.


This reaction proceeds quantitatively, such that dithionite can be determined by its conversion to Rongalite, which is far less O2-sensitive and thus easier to handle.
Rongalite C was as industrial bleaching agent and as a reducing agent for vat dyeing.
Another large-scale use is as a reducing agent in redox-initiator systems for emulsion polymerization.
Rongalite C One of the typical redox pair examples is t-butyl peroxide.


A niche use is its use as water conditioner for aquaria as it rapidly reduces chlorine and chloramine and reacts with ammonia to form the innocuous aminomethylsulfinate ion.
Rongalite, also called Rongalit is sodium hydroxymethylsulfinate, or Na+HOCH2SO2-.
The salt has many names, including also sodium formaldehyde sulfoxylate.


Rongalite is water-soluble and generally sold as the dihydrate.
Rongalite is an additive in polymers and textiles.
Rongalite is a chemical compound with the molecular formula Na+HOCH2SO2−.
Rongalite has many additional names, including Rongalit, sodium hydroxymethylsulfinate, sodium formaldehyde sulfoxylate, and Bruggolite.


Rongalite is listed in the European Cosmetics Directive as sodium oxymethylene sulfoxylate (INCI).
Rongalite is water-soluble and generally sold as the dihydrate. Rongalite and its derivatives are widely used in the dye industry.
The structure of Rongalite has been confirmed by X-ray crystallography.



USES and APPLICATIONS of RONGALITE:
Rongalite is used as printing and dyeing agent, styrene butadiene rubber and synthetic resin activator, organic matter decolorization and bleaching agent
Rongalite is mainly used as a discharging agent, color-discharging agent, reductant in printing and dyeing industry, as an activating agent for production styrene-butadise rubber and synthetic resin, also be used to decolourize and bleach some organic matters, for example: as a bleaching agent in synthetic rubber, sugar-making, and food industries.


Rongalite may be substituted for the sodium hydrosulfite in some special conditions.
Rongalite is water-soluble and generally sold as the dihydrate.
Rongalite and its derivatives are widely used in the dye industry.


Rongalite is also used in conjunction with substituted anilines (e.g. p-Anisidine [A673505]) to synthesize anilinomethanesulfonates.
Rongalite is used as a pharmaceutic aid (preservative).
Rongalite is generally used as an industrial bleaching agent for textiles, molasses, and soaps.


Rongalite also has a niche use as a water conditioner, reducing the amount of chlorine, and in pharmaceuticals as an antioxidant.
Rongalite and its derivatives are widely used in the dye industry.
The original use of Rongalite was as industrial bleaching agent and as a reducing agent for vat dyeing.


Another large-scale use is as a reducing agent in redox-initiator systems for emulsion polymerization.
One of the typical redox pair examples is t-butyl peroxide.
A niche use is its use as water conditioner for aquaria as Rongalite rapidly reduces chlorine and chloramine and reacts with ammonia to form the innocuous aminomethylsulfinate ion.


Rongalite is also used as an antioxidant in pharmaceutical formulation.
Rongalite has been used increasingly in commercial cosmetic hair dye colour removers despite the generation of formaldehyde, a known human carcinogen.
Rongalite has a variety of specialized applications in organic synthesis.


Rongalite is used primarily as an industrial bleaching agent.
Rongalite is also used as an antioxidant in pharmaceutical formulation.
Rongalite and its derivatives are widely used in the dye industry.
Cosmetic Uses: reducing agents


-Textile
In the weaving and knitting sector, Rongalite is mainly used as cellulosic printing and industrial bleach.
-Paint
Rongalite is used as an auxiliary component in boat painting materials.


-Chemistry
In the chemical industry, the redox initiator, Rongalite, is also used as an oxidant in pharmaceutical reactions.
-Water
With the mixture formed by reacting with ammonia in appropriate conditions, water treatment, Rongalite, is used especially in aquarium cleaning.


-Cosmetic
The interaction with formaldehyde is preferably used in hair dye removal processes.
-Pharmaceutical Applications:
Rongalite is a water-soluble antioxidant and is generally used as the dihydrate.
Rongalite is used in the formulation of injection products at a level of up to 0.1% w/v in the final preparation administered to the patient.



PHYSICAL AND CHEMICAL PROPERTIES OF RONGALITE:
Chemical properties translucent white orthorhombic crystal or small pieces.
Apparent density 1.80~1.85g/cm3.
Easily soluble in water, slightly soluble in alcohol.
Rongalite has strong reducibility at high temperature and can make the dyed color disappear, so it is called hanging white block.
When exposed to acid, Rongalite decomposes at 120 ℃ to produce formaldehyde, hydrogen sulfide and other toxic gases.
The water-free hanging white block is very stable, but Rongalite will gradually decompose in humid air.
The aqueous solution begins to decompose above 60°C, and the dilute solution decomposes much faster than the concentrated solution.



CHEMICAL PROPERTIES OF RONGALITE:
When freshly prepared, Rongalite occurs as white, odorless crystals, which quickly develop a characteristic garlic odor on standing.
Rongalite is a white solid; used as stripping and discharge agent for textiles.

Presenting a powerful reduction behaviour, it acts as a salt of alkaline protection.
a. Easy to deliquescent, emit heat, begin to decompose at 80°C, and sulfurated hydrogen H2S being release:
6NaHSO2·CH2O+3H2O — →4NaHSO3+2HCOONa+2H2S+HCOOH+3CH3OH

b.Decompose completely when the temperature rises to 110°C, the intramolecular formaldehyde are splitted out, and then nascent hydrogen which is possessed of the strongest reducing power are produced :
NaHSO2·CH2O —→ NaHSO2+ CH2O
NaHSO2 + H2O —→ NaHSO2+ 2[H]

c.Under the influence of acidity, decompose at PH >3, emit H2S, so that it sould be present in alkline medium PH >8.

d.Decompose on contacting oxidant, take I2 for example:
NaHSO2·CH2O+2H2O+2I2 —→ NaHSO4+4HI+CH2O



PHYSICAL PROPERTIES OF RONGALITE:
To be nominated for Ronglite is for the reason that is serves the color-discharging function fabrics as well as its appearance.
Under different cooling conditions.
Rongalite solidifies out into white lumps, powder or granules.



SOLUBILITY OF RONGALITE:
45%(20 °C):1.2 dose of water is necessary for dissolving away 1 dose of Rongalite at 20°C. 50%(70 °C):1 dose of water is necessary for dissolving avay 1 dose of Rongalite at 70°C.



REACTIONS OF RONGALITE:
Rongalite is prepared from sodium dithionite:
Na2S2O4 + 2 CH2O + H2O → NaHOCH2SO3 + NaHOCH2SO2
This reaction proceeds quantitatively, such that dithionite can be determined by its conversion to rongalite, which is far less O2-sensitive and thus easier to handle.

Rongalite can essentially be considered to be a source of SO22-.
As such Rongalite is used both as a reducing agent and as a reagent to introduce SO2 groups into organic molecules.
Treatment of elemental Se and Te with Rongalite gives solutions containing the corresponding Na2Sex and Na2Tex, where x is approximately 2.

As a nucleophile, Rongalite reacts with alkylating agents to give sulfones.
NaHOCH2SO2 + 2 C6H5CH2Br → [C6H5CH2]2SO2 + NaBr + CH2O + HBr
Occasionally, alkylation will occur also at oxygen, thus α,α' dibromoxylene gives both the sulfone and the isomeric sulfinate ester.



SYNTHESIS AND REACTIONS OF RONGALITE:
Although available commercially, Rongalite can be prepared from sodium dithionite and formaldehyde:
Na2S2O4 + 2 CH2O + H2O → HO-CH2-SO3Na + HO-CH2-SO2Na
This reaction proceeds quantitatively, such that dithionite can be determined by its conversion to Rongalite, which is far less O2-sensitive and thus easier to handle.

The hydroxymethanesulfinate ion is unstable in solution towards decomposition to formaldehyde and sulfite.
Addition of at least one equivalent of formaldehyde pushes the equilibrium towards the side of the adduct and reacts further to give the bis-(hydroxymethyl)sulfone.
Such solutions are shelf-stable indefinitely.

Rongalite was originally developed in the early 20th century for the textile industry as a shelf-stable source of sulfoxylate ion, where the latter can be generated at will.
In use, when Rongalite is made acidic, the reducing sulfoxylate ion and formaldehyde are released in equimolar amounts.
For safety reasons, the generation of formaldehyde must be taken into consideration when used industrially.

Rongalite can essentially be considered to be a source of SO22−.
As such Rongalite is used both as a reducing agent and as a reagent to introduce SO2 groups into organic molecules. Treatment of elemental Se and Te with Rongalite gives solutions containing the corresponding Na2Sex and Na2Tex, where x is approximately 2.
As a nucleophile, Rongalite reacts with alkylating agents to give sulfones.

HO-CH2-SO2Na + 2 C6H5CH2Br → [C6H5CH2]2SO2 + NaBr + CH2O + HBr
Occasionally, alkylation will occur also at oxygen, thus xylylene dibromide gives both the sulfone and the isomeric sulfinate ester.



PRODUCTION AND REACTIONS OF RONGALITE:
Interaction with caustic soda can produce white printing paste. Suitable conditions and additives can be prepared by sodium dithionite and formaldehyde.
Na2S2O4 + 2 CH2O + H2O? NaHOCH2SO3 + NaHOCH2SO2
Rongalite can be used as reducing agent thanks to the elements it contains.
NaHOCH2SO2 + 2 C6H5CH2Br? [C6H5CH2] 2SO2 + NaBr + CH2O + HBr



RELATED COMPOUNDS OF RONGALITE:
The zinc complex Zn(HOCH2SO2)2 is marketed under the trademarks Decroline, Decolin, and Safolin.
Rongalite is an additive in polymers and textiles.
Sodium hydroxymethanesulfinate is called Rongalite C. Calcium hydroxymethanesulfinate is called Rongalite H.



PURIFICATION METHODS OF RONGALITE:
Rongalite crystallises from H2O as the dihydrate and decomposes at higher temperatures.
Store Rongalite in a closed container in a cool place.
Rongalite is insoluble in EtOH and Et2O and is a good reducing agent.
Rongalite {HOCH2SO2Na} should not be confused with formaldehyde sodium bisulfite adduct {HOCH2SO3Na} from which it is prepared by reduction with Zn.
Rongalite is incompatible with strong oxidizing agents; it is decomposed by dilute acid.



PRODUCTION METHODS OF RONGALITE:
Rongalite is manufactured from sodium dithionate and formaldehyde in water.



PHYSICAL and CHEMICAL PROPERTIES of RONGALITE:
Chemical formula: CH3NaO3S
Molar mass: 118.10 g/mol
154.14 g/mol, dihydrate
Appearance: colorless crystals
Density: 1.75 g/cm3, dihydrate
Melting point: 64.5 °C (148.1 °F; 337.6 K) dihydrate
Solubility in water: 600 g/L, dihydrate (approximate)
Acidity (pKa): decomposes at low pH
Density: 1.8 g/cm3 (20 °C)
Melting Point: 63 °C
pH value: 9.5 - 10.5 (100 g/l, H₂O, 20 °C)
Vapor pressure: 2.68 hPa (20 °C)
Bulk density: 950 kg/m3
Solubility: 600 g/l
Appearance Form: solid
Odor: No data available
Odor Threshold: No data available
pH: ca.10 at > 1 g/l

Melting point/freezing point:
Melting point/range: 120 °C - dec.
Initial boiling point and boiling range: Not applicable
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: < 1 hPa at 20 °C
Vapor density: No data available
Relative density: No data available
Water solubility: 1.000 g/l at 25 °C
Partition coefficient: log Pow: < 0,3 at 22 °C
n-octanol/water: Bioaccumulation is not expected.
Autoignition temperature: does not ignite
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available

Molecular Weight: 119.10
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 1
Exact Mass: 118.97788444
Monoisotopic Mass: 118.97788444
Topological Polar Surface Area: 76.7 Ų
Heavy Atom Count: 6
Formal Charge: 1
Complexity: 42.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

Molecular Formula: HOCH2SO2Na·XH2O
Molar Mass: 118.09 (anhydrous ba
Melting Point: 64-68℃
Boling Point: 446.4℃ at 760mmHg
Flash Point: >100℃
Water Solubility: soluble H2O, alcohol [HAW93]
Appearance: White solid
PH: 9.5-10.5
Storage Condition: Inert atmosphere,Room Temperature
Stability: Stable.
Incompatible with strong oxidizing agents.
MDL: MFCD00040426
Appearance: white solid (est)
Assay: 95.00 to 100.00 %

Food Chemicals Codex Listed: No
Melting Point: 63.00 °C. @ 760.00 mm Hg (est)
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in: water, 1e+006 mg/L @ 25 °C (est)
Melting point: ~120 °C (dec.)
Density: 1.744[at 20℃]
vapor pressure 0.003Pa at 20℃
Flash point: >100℃
storage temp.: Inert atmosphere,Room Temperature
solubility: H2O: 50 mg/mL, clear, colorless
form: Solid
color: White to Off-White
PH: 9.5-10.5
Water Solubility: soluble H2O, alcohol [HAW93]
Merck: 14,8620
Stability: Stable.
Incompatible with strong oxidizing agents.
LogP: -3.4 at 22℃



FIRST AID MEASURES of RONGALITE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact: rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of RONGALITE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of RONGALITE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of RONGALITE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses.
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of RONGALITE:
-Conditions for safe storage, including any incompatibilities:
Storage conditions:
Tightly closed.
Dry.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of RONGALITE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available
-Incompatible materials:
No data available



SYNONYMS:
Sodium hydroxymethanesulfinate
Sodium formaldehydesulfoxylate
sodium oxymethylene sulfoxylate
Brüggolit
Sodium hydroxymethanesulfinate hydrate
Hydroxymethanesulfinic acid sodium salt
Rongalit
Sodium formaldehyde sulfoxylate hydrate
sodium;hydroxymethanesulfinic acid
Aldanil
Formapon
Formopan
Hydrolit
Rongalite
Rongalit C
Rongalite C
WLN: Q1SQO &-NA-
Sodium methanalsulfoxylate
Methanesulfinic acid, monosodium salt
Formaldehyde sodium sulfoxylate
Sodium sulfoxylate formaldehyde
Sodium (hydroxymethyl)sulfinate
Formaldehydesulfoxylic acid, sodium salt
Hydroxymethanesulfinic acid, sodium salt
NSC-4847
NSC4847
NSC78331
NSC-78331
Rongalite
Rongalite C
hydroxymethoxysulfinylsodium
sodium hydroxymethanesulfinate
Sodium hydroxymethanesulphinate
Formaldehyde sodium sulfoxylate
Sodium bisulfoxylate formaldehyde
Sodium hydroxymethanesulfinate hydrate
Sodium Formaldehyde Sulfoxylate Hydrate
Hydroxymethanesulfinic acid sodium salt dihydrate
formapon
hydrolit
Hydroxymethanesulfinic Acid Sodium Salt
Rongalite(R)
sodium formaldehyde sulfoxylate
Hydro AWC
FORMOSUL
formopan
sodium hydroxymethanesulfinate
Sodium formaldehydesulfoxylate
sodium rongalite
Formaldehyde Sodium Sulfoxylate Dihydrate
sodium hydroxymethanesulphinate
rongalitc
Rongalit
aldanil
FORMOPON
discolite
1-Hydroxymethanesulfinic Acid Sodium Salt Hydrate
Hydroxymethanesulfinic Acid Monosodium Salt Hydrate
Sodium Formaldehydesulfoxylate Hydrate
Aldanil Hydrate
Formaldehyde Sodium Sulfoxylate Hydrate
Formaldehydesulfoxylic Acid Sodium Salt Hydrate
Formopan Hydrate
Hydrolit Hydrate
Hydroxymethanesulfinic Acid Sodium Salt Hydrate
Langqielie C Hydrate; Leptacid Hydrate
Redol C Hydrate
Rodite Hydrate
Rongalit C Hydrate
Rongalite Hydrate
Rongalite C Hydrate
Sodium (hydroxymethyl)sulfinate Hydrate
Sodium Hydroxymethanesulfinate Hydrate
Sodium Methanalsulfoxylate Hydrate
Sodium Sulfoxylate Formaldehyde Hydrate
RONGALITE
SODIUM FORMALDEHYDE SULFOXYLATE
SODIUM HYDROXYMETHANESULFINATE
RONGALITE C
SODIUM FORMALDEHYDESULFOXALATE
Natriumhydroxymethansulfinat
Sodiumbisulfoxylateformaldehyde
Sodium hydroxymethanesulfinate hydrate
HYDROXYMETHANESULFINIC ACID SODIUM SALT
aldanil

RONGALITE

Rongalite is a chemical compound with the formula Na_2[O_2C_6H_3(SO_3Na)_2]·3H_2O.
Rongalite is a white crystalline powder that is soluble in water and commonly used as a reducing agent in various industrial applications.
Rongalite is a white crystalline powder with a sulfur dioxide-like odor.

CAS Number: 149-44-0
EC Number: 205-755-3



APPLICATIONS


Rongalite is commonly used as a reducing agent in the textile industry for printing, dyeing, and bleaching.
Rongalite is used as a bleaching agent in paper manufacturing.
Rongalite is used in photography to develop photographic prints and films.

Rongalite is also used as a reducing agent in the synthesis of organic compounds in the chemical industry.
Rongalite is used as a catalyst in the production of acrylic fibers.

Rongalite is used in the preparation of chemicals like sulfa drugs and dyes.
Rongalite is used to reduce the oxygen content in metal extraction processes, such as the production of copper and nickel.

Rongalite is used as a reducing agent in the synthesis of nanoparticles.
Rongalite is used in the production of inkjet inks and toners.

Rongalite is used in the production of photovoltaic cells for solar energy.
Rongalite is used as a reducing agent in the synthesis of pharmaceuticals.
Rongalite is used as a decolorizing agent in the sugar industry.

Rongalite is used in the electroplating industry for the deposition of metals like copper, gold, and silver.
Rongalite is used in the manufacturing of electronic components like printed circuit boards.

Rongalite is used in the production of ceramics and glass.
Rongalite is used in the manufacturing of agrochemicals and pesticides.

Rongalite is used in the oil and gas industry for the reduction of sulfur content in crude oil.
Rongalite is used in the pulp and paper industry for the reduction of chlorine content in the bleaching process.

Rongalite is used in the leather industry for the preparation of leather dyes and tanning agents.
Rongalite is used in the cosmetic industry for the preparation of hair dyes and hair care products.
Rongalite is used in the food industry as a reducing agent for the preparation of canned and frozen foods.

Rongalite is used in the production of water treatment chemicals like flocculants and coagulants.
Rongalite is used in the purification of natural gas and biogas.

Rongalite is used in the manufacture of detergents and cleaning agents.
Rongalite is used in the textile industry for the reduction of environmental pollution caused by the use of traditional reducing agents.


Rongalite, also known as sodium hydroxymethanesulfinate, has a variety of specific applications in different industries.
Some of its specific applications are:

Textile industry:

Rongalite is used as a reducing agent for the printing and dyeing of textiles.
Rongalite is effective in removing excess dyes and producing vibrant colors.


Photography industry:

Rongalite is used as a reducing agent in photographic processing.
Rongalite helps to reduce the silver halide to form a black and white image.


Paper industry:

Rongalite is used as a bleaching agent in the paper industry.
Rongalite helps to brighten the color of the paper and improve its overall appearance.


Food industry:

Rongalite is used as a preservative in the food industry.
Rongalite helps to prevent the oxidation of food and increase its shelf life.


Polymer industry:

Rongalite is used as a reducing agent in the production of polymers.
Rongalite helps to control the molecular weight and improve the properties of the final product.


Water treatment:

Rongalite is used in the treatment of wastewater and industrial effluent.
Rongalite is effective in reducing heavy metal ions and removing impurities from the water.


Pharmaceutical industry:

Rongalite is used as a reducing agent in the synthesis of pharmaceuticals.
Rongalite helps to control the purity and improve the yield of the final product.


Agriculture industry:

Rongalite is used as a plant growth regulator in the agriculture industry.
Rongalite helps to improve the yield and quality of crops.


Cosmetic industry:

Rongalite is used as a reducing agent in the production of cosmetics.
Rongalite helps to control the color and consistency of the final product.


Mining industry:

Rongalite is used as a reducing agent in the mining industry.
Rongalite helps to extract metals from ores and improve the efficiency of the process.


Rongalite (Sodium Formaldehyde Sulfoxylate) has several applications across various industries.
Some of its applications are:

As a reducing agent in the textile industry for bleaching, dyeing, and printing cotton and wool fabrics.
As a reducing agent in the paper and pulp industry for the manufacture of specialty papers.
As a photographic developer in the photographic industry.

As a polymerization inhibitor in the production of polyesters, acrylics, and vinyl acetate.
As a depilatory agent in the leather industry for removing hair from hides.

As a reductant in the synthesis of organic chemicals.
As an oxygen scavenger in the food packaging industry.

As a reducing agent in electroplating processes.
As a preservative for cut flowers.
As a bleach in the chemical industry for the production of chemical intermediates.

As a reducing agent for the synthesis of various metal nanoparticles.
As an additive in the production of organic semiconductors.

As a reducing agent in the preparation of nanocomposites.
As an agent for the preparation of nanoscale magnetic materials.

As a reducing agent in the preparation of metal nanoparticles for catalysis.
As a depilatory agent in the fur and wool industry.
As a reducing agent for the preparation of metal oxides and sulfides.

As a reducing agent in the synthesis of ceramic materials.
As a stabilizer for hydrogen peroxide in the pulp and paper industry.

As a reducing agent in the production of silver nanoparticles for antimicrobial applications.
As a reducing agent for the preparation of graphene-based materials.

As a bleaching agent in the production of cellulose and starch-based products.
As a reducing agent for the preparation of metal-carbon nanocomposites.

As a reducing agent for the synthesis of magnetic nanoparticles for biomedical applications.
As an additive in the production of flame retardants for textiles.

Rongalite is used as a reducing agent in the synthesis of various organic compounds.
Rongalite is used in the textile industry for the reduction of vat dyes.
Rongalite is used in the pulp and paper industry for bleaching purposes.

Rongalite is used in the production of photographic films as a reducing agent.
Rongalite is used in the preparation of metal complexes in the chemical industry.

Rongalite is used as a laboratory reagent for the reduction of organic compounds.
Rongalite is used in the preparation of medicines and pharmaceuticals.
Rongalite is used as a stabilizer for rubber products.

Rongalite is used in the synthesis of inorganic pigments.
Rongalite is used in the production of pesticides and insecticides.

Rongalite is used in the synthesis of corrosion inhibitors.
Rongalite is used in the electroplating industry as a reducing agent.

Rongalite is used in the treatment of industrial wastewater.
Rongalite is used in the manufacturing of hair dyes.
Rongalite is used as an oxygen scavenger in boiler water treatment.

Rongalite is used in the production of flame retardants.
Rongalite is used in the synthesis of organic peroxides.

Rongalite is used in the preparation of plasticizers.
Rongalite is used in the production of rubber chemicals.

Rongalite is used as a photographic fixing agent.
Rongalite is used in the synthesis of surface-active agents.

Rongalite is used as a color developing agent in photography.
Rongalite is used in the preparation of detergents and soaps.

Rongalite is used as a reagent for the determination of heavy metals.
Rongalite is used in the manufacturing of surfactants.



DESCRIPTION


Rongalite is a chemical compound with the formula Na_2[O_2C_6H_3(SO_3Na)_2]·3H_2O.
Rongalite is a white crystalline powder that is soluble in water and commonly used as a reducing agent in various industrial applications.

Rongalite is a white crystalline powder with a sulfur dioxide-like odor.
Rongalite is also known as sodium formaldehyde sulfoxylate or Na2S2O4.
The chemical formula for Rongalite is Na2O4S2.

Rongalite is soluble in water and insoluble in organic solvents.
Rongalite is a strong reducing agent, capable of reducing many metals and metal ions.

Rongalite is used in the textile industry for bleaching, reducing, and dyeing cotton.
Rongalite is also used in the paper industry as a reducing agent for the bleaching of wood pulp.
Rongalite is used in photography as a reducing agent to develop photographic negatives.

Rongalite is used in electroplating to reduce metal ions to their metallic state.
Rongalite is used in the production of pharmaceuticals and chemicals.

Rongalite is used in the manufacture of sulfur dyes and pigments.
Rongalite is used in the leather industry for the reduction of chromium ions in tanning.

Rongalite is used in water treatment as a reducing agent for the removal of chlorine.
Rongalite is used as a reducing agent in the synthesis of organic compounds.
Rongalite is used as a bleaching agent for the production of food and beverages.

Rongalite is used in the production of adhesives, resins, and coatings.
Rongalite is used as a reducing agent for the synthesis of nanoparticles.

Rongalite is used in the production of detergents and cleaning agents.
Rongalite is used in the manufacturing of polymers and plastics.

Rongalite is used in the oil and gas industry for reducing sulfur content in crude oil and natural gas.
Rongalite is used in the production of batteries and fuel cells.
Rongalite is used in the production of electronic components and semiconductors.

Rongalite is used in the manufacturing of explosives and pyrotechnics.
Rongalite is used as a reducing agent for the recovery of precious metals.
Rongalite is used in the preservation of cultural heritage artifacts.



PROPERTIES


Chemical formula: Na2S2O4 · 2H2O
Molecular weight: 174.11 g/mol
Appearance: White to off-white crystalline powder
Odor: Odorless
Density: 2.36 g/cm3
Melting point: 52-54 °C
Solubility in water: Soluble
pH (1% solution): 5.5-7.5
Solubility in other solvents: Soluble in glycerol and methanol, slightly soluble in ethanol and acetone, insoluble in ether
Stability: Stable under normal conditions of use and storage, but may decompose on exposure to heat or light
Hazardous decomposition products: Sulfur dioxide and other sulfur compounds
Flash point: Not applicable (non-flammable)
Autoignition temperature: Not applicable (non-flammable)
Vapor pressure: Negligible
Boiling point: Decomposes before boiling
Specific gravity: 2.36
Viscosity: Not applicable (solid)
Refractive index: Not applicable (solid)
Heat of combustion: Not applicable (non-combustible)
Heat of vaporization: Not applicable (non-volatile)
Heat of fusion: Not applicable (decomposes before melting)
Electrical conductivity: Not applicable (insulator)
Magnetic properties: Not applicable (non-magnetic)
Optical properties: Not applicable (solid)
Radioactivity: Not radioactive
Toxicity: May cause irritation to eyes, skin, and respiratory tract. May be harmful if ingested or inhaled in large quantities.



FIRST AID


Inhalation:

If inhaled, move the person to fresh air immediately.
If the person is not breathing, call for emergency medical attention and provide artificial respiration.
Seek medical attention if symptoms such as coughing, shortness of breath, or wheezing persist.


Skin contact:

Remove contaminated clothing and wash affected area thoroughly with soap and water.
Seek medical attention if irritation, redness, or pain occurs.


Eye contact:

Flush eyes with plenty of water for at least 15 minutes while holding the eyelids open.
Seek medical attention if irritation, redness, or pain persists.


Ingestion:

Rinse mouth with water and drink plenty of water.
Do not induce vomiting unless instructed to do so by medical personnel.

Seek medical attention immediately.
Note: Never give anything by mouth to an unconscious person.


General:

Remove contaminated clothing immediately.
Wash hands thoroughly after handling.

Contaminated work clothes should be laundered before reuse.
Store and handle the chemical in accordance with safety regulations and manufacturer instructions.



HANDLING AND STORAGE


Handling:

Wear appropriate personal protective equipment (PPE), such as gloves and goggles, when handling Rongalite.
Avoid contact with skin, eyes, and clothing.
If contact occurs, immediately remove contaminated clothing and flush the affected area with water for at least 15 minutes.

Use caution when handling Rongalite around heat sources or open flames, as it may decompose and release harmful gases.
Avoid inhalation of dust or vapors from Rongalite.

Use in a well-ventilated area or use respiratory protection if necessary.
Do not eat, drink, or smoke in areas where Rongalite is being used or stored.


Storage:

Store Rongalite in a cool, dry, well-ventilated area away from incompatible materials.
Keep containers tightly closed when not in use.
Store away from heat sources and open flames.

Do not store with strong oxidizing agents, acids, or alkalies.
Follow all applicable regulations for storage and disposal of Rongalite.



SYNONYMS


Sodium hydroxymethanesulfinate
Sodium formaldehyde sulfoxylate
Sodium oxymethylene sulfoxylate
Sodium hydroxymethylsulfinic acid
Sodium formaldehyde sulphinic acid
Sodium formaldehyde bisulfite
Formaldehyde sodium bisulfite
Hydroxymethanesulfonate sodium
Formosulfinates
Formalsulfinates
FAS
SHS
Hydroxymethanesulfonate
Sodium sulfoxylate formaldehyde
Sodium formaldehyde sulfoxylate dihydrate
Sodium oxymethylene sulfoxylate dihydrate
Sodium hydroxymethyl sulfinic acid dihydrate
Sodium formaldehyde sulfinic acid dihydrate
Sodium formaldehyde bisulfite dihydrate
Formaldehyde sodium bisulfite dihydrate
Hydroxymethanesulfonate sodium dihydrate
Formosulfinates dihydrate
Formalsulfinates dihydrate
SFS
SHS dihydrate
Sodium formaldehyde sulfoxylate
Sodium oxymethylene sulfoxylate
Formaldehyde sodium bisulfite
Sodium formylhydroxylamine
Sodium formaldehyde bisulfite
Sodium bisulfite formaldehyde
Sodium oxymethyl sulfoxylate
Sodium sulfoxylate formaldehyde
Sodium formaldehyde sulfoxylate dihydrate
Sodium hydroxymethylene sulfoxylate
Sodium oxymethylsulfonate
Sodium sulfoxymethylate
Sodium oxymethylsulfinate
Sodium formylhydroxamate
Sodium formylhydroxylamine sulfonate
Formaldehyde sodium sulfoxylate dihydrate
Sodium oxymethylene sulfonate
Sodium oxymethylene sulfinate
Sodium oxymethylene sulphinic acid
Sodium sulfinylmethane
Sodium formaldehydesulfoxylate dihydrate
Sodium formaldehydesulphoxylate
Sodium formylhydroxylammonium
Sodium bisulphite formaldehyde
Sodium formaldehydesulphoxylate dihydrate

ROPAQUE OPAQUE POLYMER
ROPAQUE Opaque Polymer is a chemical compound that is used to remove sodium salts from water in the treatment of wastewater.
ROPAQUE Opaque Polymer is also an analytical reagent for the determination of ammonium ions by titration, and is used as a polymerization catalyst.
ROPAQUE Opaque Polymer can be used to produce glycol ethers, which are solvents with low toxicity and high boiling points.

CAS: 1336-21-6
MF: H5NO
MW: 35.05
EINECS: 215-647-6

Synonyms
Ammonium hydroxide solution, 25% NH3, 99.99% trace metals basis;Ammonium hydroxide solution, 20-22% NH3, Environmental;Ammonium hydroxide solution, 28.0-30.0% NH3, ACS;Ammonium hydroxide solution, volumetric, 5.0N in water;1mol/l-Ammonia Solution;Ammonia concentrate;AMMONIUM HYDROXIDE SOLUTION, 1 M IN;AMMONIUM HYDROXIDE, 28% NH3 IN WATER, 99;ammonium hydroxide;1336-21-6;Ammonia aqueous;Ammonia water;Aquammonia;Aqua ammonia;Ammonia, aqua;Household ammonia;Ammonia, monohydrate;Ammonia water 29%;Ammoniumhydroxid;Caswell No. 044;Ammonium hydroxide ((NH4)(OH));SX 1 (ammonia water);ammoniaque;SX 1;NH4OH;HSDB 5125;agua de amoniaco;EINECS 215-647-6;hidroxido de amonio;hydroxyde d'ammonium;EPA Pesticide Chemical Code 005301;DTXSID4020080;CHEBI:18219;EC 215-647-6;E527;ammoniumhydroxide;MFCD00066650;Ammonia, aqueous;Hydroxide, Ammonium;Ammonia water [JAN];UN2672;UN3318;NH(4)OH;ammonia hydrate;water ammonia;ammonium hydoxide;ammonium hydroxid;ammonium hyroxide;amonium hydroxide;ammonium hydorxide;amrnonium hydroxide;NH3 water;water NH3;UN2073;Ammonia water (TN);Ammonium aqueous (28% or less NH3);AMINE HYDRATE;Ammonium hydroxide (28% or less ammonia);Ammonia water (JP17);DTXCID8080;NH3 H2O;NH3-H2O;NH3.H2O;Ammonium hydroxide, 25% NH3;AMMONIUM HYDROXIDE (II)
;Ammonia (ammonium hydroxide) 28% by weight or more NH3;VHUUQVKOLVNVRT-UHFFFAOYSA-N;AKOS015903971;AKOS030228272;NS00075653;C01358;D04594;J-006420

ROPAQUE Opaque Polymer Chemical Properties
Melting point: -77°C
Boiling point: 36°C
Density: 0.91 g/mL at 20 °C
Vapor density: 1.2 (vs air)
Vapor pressure: 115 mmHg at 20 °C for 29% solution
Storage temp.: 2-8°C
Solubility: Water (Soluble)
Form: Liquid, Single Sub-Boiling Quartz Distillation
pka: 9.3(at 25℃)
Color: Colorless
Specific Gravity: approximate 0.96 (10%, 15℃)
PH: 10.09(1 mM solution);10.61(10 mM solution);11.12(100 mM solution);
Odor: Strong pungent ammonia odor detectable at 17 ppm
Explosive limit: 27%
Water Solubility: Miscible with water.
λmax λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01
Merck: 14,494
BRN: 3587154
Stability: Stable. Incompatible with copper, copper alloys, acids, galvanised iron, zinc, aluminium, bronze, dimethyl sulphate, mercury, alkali metals.
InChIKey: VHUUQVKOLVNVRT-UHFFFAOYSA-N
CAS DataBase Reference: 1336-21-6(CAS DataBase Reference)
EPA Substance Registry System: ROPAQUE Opaque Polymer (1336-21-6)

Composition and Properties:
ROPAQUE Opaque Polymer is an aqueous solution composed of ammonia gas (NH3) dissolved in water.
The concentration of ammonia can vary depending on the specific application requirements.
ROPAQUE Opaque Polymer is colorless with a strong, pungent odor.
ROPAQUE Opaque Polymer has a density of approximately 0.9 g/mL and is highly water-soluble.
The presence of ROPAQUE Opaque Polymer can increase the pH level of water due to its basic nature.
ROPAQUE Opaque Polymer is important to handle the product with proper precautions as it is highly corrosive and can cause severe skin and eye irritation.

ROPAQUE Opaque Polymer exists only in the form of an aqueous solution.
ROPAQUE Opaque Polymer is prepared by dissolving NH3 in H2O and usually is referred to in industrial trade as aqua ammonia.
For industrial procurements, the concentration of NH3 in solution is normally specified in terms of the specific gravity (degrees Baum′e, °Be).
Common concentrations are 20 °Be and 26 °Be.
The former is equivalent to a sp gr of 0.933, or a concentration of about 17.8% NH3 in solution; the latter is equivalent to a sp gr of 0.897, or a concentration of about 29.4% NH3.
These figures apply at a temperature of 60 °F (15.6 °C).
Reagent grade NH4OH usually contains approximately 58% NH4OH (from 28 to 30% NH3 in solution).

The reaction mechanism involves the conversion of hydrogen fluoride (HF) to hydrofluoric acid (HF), which reacts with ammonia to form ammonium fluoride (NH4F).
This reaction produces heat and gives off water vapor.
ROPAQUE Opaque Polymer is a weak base, so it will react with any strong acid, such as hydrochloric acid or sulfuric acid, but not with weak acids such as acetic acid or phosphoric acid.
A non film-forming, low-odor synthetic pigment engineered to improve the economics of waterborne coatings.
ROPAQUE Opaque Polymer shows increased light scattering efficiency compared to previous Opaque Polymer products, while maintaining paint performance.
The addition of ROPAQUE Opaque Polymer to paints allows for the formulator to remove TiO2 in a paint while maintaining the same level of dry hiding in the coating.

ROPAQUE Opaque Polymer have a narrow particle size distribution and are similar in size
to TiO2 particles.
This allows them to act like ultra fine inorganic extenders, spacing TiO2 effectively and therefore increasing its efficiency as a primary pigment.
Compared to inorganic small particle size pigment extenders, ROPAQUE Opaque Polymer
have a very low specific surface area due to their uniform, spherical shape and non porous
surface.
The binder demand of ROPAQUE Opaque Polymer is therefore significantly lower, giving the possibility of formulating at higher pigment volume concentrations.
The combined effect of these three product features can be used by paint formulators to
either reduce paint cost without negative effect on paint performance, or alternatively,
improve paint performance without increasing costs.
Light scattering theory shows that the two parameters most impacting the hiding efficiency
are the particle size of the hollow spheres and the void fraction.

The optimum light scattering efficiency is obtained at a particle diameter of roughly 0.40µm.
The innovative process used to manufacture ROPAQUE Opaque Polymer enables an optimum particle size (0.38µm) with a maximized void fraction of 44%.
ROPAQUE Opaque Polymer represents excellent performance for a polymeric opacifying agent.
Like its predecessors, ROPAQUE Opaque Polymer, is a hollow sphere polymeric pigment allowing paint manufacturers to reduce the raw material cost of their formulations with no performance penalties.
It maintains the same efficiency and light scattering ability of ROPAQUE Opaque Polymer, with the added advantage of being ammonia free.
In addition to offering very efficient dry opacity properties, ROPAQUE Opaque Polymer offers a wide range of benefits in interior and exterior paint formulations and can be
used as a ‘drop in’ replacement for ROPAQUE ULTRA Opaque Polymer.
ROPAQUE Opaque Polymer is a colorless aqueous solution.
Concentration of ammonia ranges up to approximately 30%.
ROPAQUE Opaque Polymer vapors (which arise from the solution) irritate the eyes.

ROPAQUE Opaque Polymer is a colorless, liquid solution with a characteristic and pungent odor.
ROPAQUE Opaque Polymer is ammonia combined with water.
ROPAQUE Opaque Polymer is a compound consisting of nitrogen and hydrogen.
Both ROPAQUE Opaque Polymer and ammonium hydroxide are very common compounds, found naturally in the environment (in air, water, and soil) and in all plants and animals, including humans.
ROPAQUE Opaque Polymer is a source of nitrogen, an essential element for plants and animals.
ROPAQUE Opaque Polymer is also produced by the human body – by our organs and tissues and by beneficial bacteria living in our intestines.
ROPAQUE Opaque Polymer plays an important role in protein synthesis in the human body.

In brief summary, all living things need proteins, which are comprised of some 20 different amino acids.
While plants and microorganisms can synthesize most amino acids from the nitrogen in the atmosphere, animals cannot.
For humans, ROPAQUE Opaque Polymer cannot be synthesized at all and must be consumed as intact amino acids.
Other amino acids, however, can be synthesized by microorganisms in the gastrointestinal tract with the help of ammonia ions.
Thus, ROPAQUE Opaque Polymer is a key player in the nitrogen cycle and in protein synthesis.
ROPAQUE Opaque Polymer also helps maintain the body's pH balance.
ROPAQUE Opaque Polymer, also known as ammonia water, ammonium hydroxide, ammoniacal liquor, ammonia liquor, aqua ammonia, aqueous ammonia, or (inaccurately) ammonia, is a solution of ammonia in water.

ROPAQUE Opaque Polymer can be denoted by the symbols NH3(aq).
Although the name ROPAQUE Opaque Polymer suggests an alkali with composition [NH4+][OH−], it is actually impossible to isolate samples of NH4OH.
The ions NH4+ and OH− do not account for a significant fraction of the total amount of ammonia except in extremely dilute solutions.
Diluted (1–3%) ROPAQUE Opaque Polymer is also an ingredient of numerous cleaning agents, including many window cleaning formulas.
Because aqueous ammonia is a gas dissolved in water, as the water evaporates from a window, the gas evaporates also, leaving the window streak-free.
In addition to use as an ingredient in cleansers with other cleansing ingredients, ROPAQUE Opaque Polymer in water is also sold as a cleaning agent by itself, usually labeled as simply “ammonia”.
ROPAQUE Opaque Polymer may be sold plain, lemon-scented (and typically colored yellow), or pine-scented (green).

Uses
ROPAQUE Opaque Polymer is widely utilized as a leavening agent or acidity regulator in food production.
ROPAQUE Opaque Polymer serves as a precursor to some alkyl amines and is also used in the tobacco industry for flavor enhancement and as a processing aid.
During furniture making, ROPAQUE Opaque Polymer combines with tannic acid and is used to darken or stain wood by making it iron salts.
In chemical laboratories, ROPAQUE Opaque Polymer used for qualitative inorganic analysis, as a complexant and as a base.
ROPAQUE Opaque Polymer is used to clean gold, silve, and platinum jewelry.
ROPAQUE Opaque Polymer is an active component of Tollens' reagent (consisting of a solution of silver nitrate and ammonia) and is used to determine the presence of aldehyde or alpha-hydroxy ketone functional groups.

ROPAQUE Opaque Polymer is used as a cleaning agent and sanitizer in many household and industrial cleaners.
ROPAQUE Opaque Polymer is also used in the manufacture of products such as fertilizer, plastic, rayon and rubber.
ROPAQUE Opaque Polymer is corrosive to aluminum alloys, copper, copper alloys, and galvanized surfaces.
ROPAQUE Opaque Polymer is an excellent acid neutralizer.
ROPAQUE Opaque Polymer is an alkaline that is a clear, colorless solu- tion of ammonia which is used as a leavening agent, a ph control agent, and a surface finishing agent.
ROPAQUE Opaque Polymer is used in baked goods, cheese, puddings, processed fruits, and in the production of caramels.
ROPAQUE Opaque Polymer is widely used in various industries for its versatile properties.
Some of the key applications include:

Laboratory Research: ROPAQUE Opaque Polymer is commonly used as a reagent in laboratories for various analytical and synthetic chemistry applications.
ROPAQUE Opaque Polymer's ability to adjust the pH level of solutions makes it an essential tool in many reactions and experiments.
Manufacturing: ROPAQUE Opaque Polymer is a crucial ingredient in the production of various products such as fertilizers, pharmaceuticals, dyes, and detergents.
ROPAQUE Opaque Polymeris often used as a nitrogen source in fertilizers and plays a vital role in enhancing growth and yield in agricultural practices.
Metal Processing: ROPAQUE Opaque Polymer is widely employed in metal processing and cleaning operations.
ROPAQUE Opaque Polymer is particularly effective in removing metal oxides and scales from surfaces, making it an excellent choice for pickling, electroplating, and etching processes.

Waste Water Treatment: The strong basic nature of ROPAQUE Opaque Polymer makes it an important component in wastewater treatment plants.
ROPAQUE Opaque Polymer is used for pH adjustment in both industrial and municipal treatment facilities.
ROPAQUE Opaque Polymer helps neutralize acidic wastewater and facilitates the removal of heavy metals and other contaminants.
Household Applications: ROPAQUE Opaque Polymer can be found in common household products such as glass cleaners and oven and drain cleaners.
ROPAQUE Opaque Polymer's powerful cleaning properties make it effective in removing stubborn stains and dirt.
ROPAQUE ULTRA
ROPAQUE Ultra expands the boundaries of light scattering technology, providing the most efficient dry hiding in interior and exterior coatings.
Additionally, ROPAQUE Ultra non-film-forming synthetic pigment is specially engineered to improve the economics of waterborne coatings while maintaining coating performance.
Like its predecessors, ROPAQUE Ultra is a hollow-sphere polymeric pigment that allows paint manufacturers to reduce the raw material cost of their formulations with no performance penalties.

CAS: 1336-21-6
MF: H5NO
MW: 35.05
EINECS: 215-647-6

Synonyms
Ammonium hydroxide solution, 25% NH3, 99.99% trace metals basis;Ammonium hydroxide solution, 20-22% NH3, Environmental;Ammonium hydroxide solution, 28.0-30.0% NH3, ACS;Ammonium hydroxide solution, volumetric, 5.0N in water;1mol/l-Ammonia Solution;Ammonia concentrate;AMMONIUM HYDROXIDE SOLUTION, 1 M IN;AMMONIUM HYDROXIDE, 28% NH3 IN WATER, 99;ammonium hydroxide;1336-21-6;Ammonia aqueous;Ammonia water;Aquammonia;Aqua ammonia;Ammonia, aqua;Household ammonia;Ammonia, monohydrate;Ammonia water 29%;Ammoniumhydroxid;Caswell No. 044;Ammonium hydroxide ((NH4)(OH));SX 1 (ammonia water);ammoniaque;SX 1;NH4OH;HSDB 5125;agua de amoniaco;EINECS 215-647-6;hidroxido de amonio;hydroxyde d'ammonium;EPA Pesticide Chemical Code 005301;DTXSID4020080;CHEBI:18219;EC 215-647-6;E527;ammoniumhydroxide;MFCD00066650;Ammonia, aqueous;Hydroxide, Ammonium;Ammonia water [JAN];UN2672;UN3318;NH(4)OH;ammonia hydrate;water ammonia;ammonium hydoxide;ammonium hydroxid;ammonium hyroxide;amonium hydroxide;ammonium hydorxide;amrnonium hydroxide;NH3 water;water NH3;UN2073;Ammonia water (TN);Ammonium aqueous (28% or less NH3);AMINE HYDRATE;Ammonium hydroxide (28% or less ammonia);Ammonia water (JP17);DTXCID8080;NH3 H2O;NH3-H2O;NH3.H2O;Ammonium hydroxide, 25% NH3;AMMONIUM HYDROXIDE (II)
;Ammonia (ammonium hydroxide) 28% by weight or more NH3;VHUUQVKOLVNVRT-UHFFFAOYSA-N;AKOS015903971;AKOS030228272;NS00075653;C01358;D04594;J-006420

ROPAQUE Ultra are the most efficient products in the ROPAQUE Opaque Polymer product family.
The only difference between ROPAQUE Ultra is the neutralizer.
ROPAQUE Ultra is neutralized with ammonia, and ROPAQUE Ultra is neutralized with sodium hydroxide.
In addition to providing the most efficient dry-hiding properties, ROPAQUE Ultra offers wide range benefits in interior and exterior paint formulations.
ROPAQUE Ultra is a non-film forming, acrylic polymer hollow-sphere opaque pigment allowing manufactures to reduce formulation costs without sacrificing properties by being one of the most efficient dry hiding capabilities for interior and exterior coatings.
ROPAQUE Ultra is neutralized with sodium hydroxide.

ROPAQUE Ultra, also known as ammonia water, ammonium hydroxide, ammoniacal liquor, ammonia liquor, aqua ammonia, aqueous ammonia, or (inaccurately) ammonia, is a solution of ammonia in water.
ROPAQUE Ultra can be denoted by the symbols NH3(aq).
Although the name ROPAQUE Ultra suggests an alkali with the composition [NH+4][OH−], it is actually impossible to isolate samples of NH4OH.
The ions NH+4 and OH− do not account for a significant fraction of the total amount of ammonia except in extremely dilute solutions.

ROPAQUE Ultra is a chemical compound that is used to remove sodium salts from water in the treatment of wastewater.
ROPAQUE Ultra is also an analytical reagent for the determination of ammonium ions by titration, and is used as a polymerization catalyst.
ROPAQUE Ultra can be used to produce glycol ethers, which are solvents with low toxicity and high boiling points.
The reaction mechanism involves the conversion of hydrogen fluoride (HF) to hydrofluoric acid (HF), which reacts with ammonia to form ammonium fluoride (NH4F).
This reaction produces heat and gives off water vapor.
ROPAQUE Ultra is a weak base, so it will react with any strong acid, such as hydrochloric acid or sulfuric acid, but not with weak acids such as acetic acid or phosphoric acid.

ROPAQUE Ultra Chemical Properties
Melting point: -77°C
Boiling point: 36°C
Density: 0.91 g/mL at 20 °C
Vapor density: 1.2 (vs air)
Vapor pressure: 115 mmHg at 20 °C for 29% solution
Storage temp.: 2-8°C
Solubility: Water (Soluble)
Form: Liquid, Single Sub-Boiling Quartz Distillation
pka: 9.3(at 25℃)
Color: Colorless
Specific Gravity: approximate 0.96 (10%, 15℃)
PH: 10.09(1 mM solution);10.61(10 mM solution);11.12(100 mM solution);
Odor: Strong pungent ammonia odor detectable at 17 ppm
Explosive limit: 27%
Water Solubility: Miscible with water.
λmax λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01
Merck: 14,494
BRN: 3587154
Stability: Stable. Incompatible with copper, copper alloys, acids, galvanised iron, zinc, aluminium, bronze, dimethyl sulphate, mercury, alkali metals.
InChIKey: VHUUQVKOLVNVRT-UHFFFAOYSA-N
CAS DataBase Reference: 1336-21-6(CAS DataBase Reference)
EPA Substance Registry System: ROPAQUE Ultra (1336-21-6)

Uses
In contrast to anhydrous ammonia, aqueous ammonia finds few non-niche uses outside of cleaning agents.

Household cleaner
ROPAQUE Ultra is also an ingredient of numerous cleaning agents, including many window cleaning formulas.
Because ROPAQUE Ultra is a gas dissolved in water, as the water evaporates from a window, the gas evaporates also, leaving the window streak-free.
In addition to use as an ingredient in cleansers with other cleansing ingredients, ammonia in water is also sold as a cleaning agent by itself, usually labeled as simply "ammonia".
ROPAQUE Ultra may be sold plain, lemon-scented (and typically colored yellow), or pine-scented (green). Commonly available ammonia with soap added is known as "cloudy ammonia".

Alkyl amine precursor
In industry, ROPAQUE Ultra can be used as a precursor to some alkyl amines, although anhydrous ammonia is usually preferred.
Hexamethylenetetramine forms readily from ROPAQUE Ultra and formaldehyde.
Ethylenediamine forms from 1,2-dichloroethane and ROPAQUE Ultra.

Absorption refrigeration
In the early years of the twentieth century, the vapor absorption cycle using water-ammonia systems was popular and widely used, but after the development of the vapor compression cycle ROPAQUE Ultra lost much of its importance because of its low coefficient of performance (about one fifth of that of the vapor compression cycle).
Both the Electrolux refrigerator and the Einstein refrigerator are well known examples of this application of the ammonia solution.

Water treatment
ROPAQUE Ultra is used to produce chloramine, which may be utilised as a disinfectant.
In drinking water, chloramine is preferred over direct chlorination for its ability to remain active in stagnant water pipes longer, thereby reducing the risk of waterborne infections.
ROPAQUE Ultra is used by aquarists for the purposes of setting up a new fish tank using an ammonia process called fishless cycling.
This application requires that the ammonia contain no additives.

Food production
Baking ROPAQUE Ultra (ammonium carbonate and ammonium bicarbonate) was one of the original chemical leavening agents.
ROPAQUE Ultra was obtained from deer antlers.
ROPAQUE Ultra is useful as a leavening agent, because ammonium carbonate is heat activated.
ROPAQUE Ultra characteristic allows bakers to avoid both yeast's long proofing time and the quick CO2 dissipation of baking soda in making breads and cookies rise.
ROPAQUE Ultra is still used to make ammonia cookies and other crisp baked goods, but its popularity has waned because of ammonia's off-putting smell and concerns over its use as a food ingredient compared to modern-day baking powder formulations.
ROPAQUE Ultra has been assigned E number E527 for use as a food additive in the European Union.
ROPAQUE Ultra is used as an acidity regulator to bring down the acid levels in food.
ROPAQUE Ultra is classified in the United States by the Food and Drug Administration as generally recognized as safe (GRAS) when using the food grade version.
ROPAQUE Ultra's pH control abilities make it an effective antimicrobial agent.

Furniture darkening
In furniture-making, ROPAQUE Ultra fuming was traditionally used to darken or stain wood containing tannic acid.
After being sealed inside a container with the wood, fumes from the ROPAQUE Ultra solution react with the tannic acid and iron salts naturally found in wood, creating a rich, dark stained look to the wood.
This technique was commonly used during the arts and crafts movement in furniture – a furniture style which was primarily constructed of oak and stained using these methods.

Treatment of straw for cattle
ROPAQUE Ultra is used to treat straw, producing "ammoniated straw" making it more edible for cattle.

Laboratory use
ROPAQUE Ultra is used in traditional qualitative inorganic analysis as a complexant and base. Like many amines, ROPAQUE Ultra gives a deep blue coloration with copper(II) solutions.
Ammonia solution can dissolve silver oxide residues, such as those formed from Tollens' reagent.
ROPAQUE Ultra is often found in solutions used to clean gold, silver, and platinum jewelry, but may have adverse effects on porous gem stones like opals and pearls.

Basicity of ROPAQUE Ultra in water
In aqueous solution, ammonia deprotonates a small fraction of the water to give ammonium and hydroxide according to the following equilibrium:

NH3 + H2O ↽⇀{\displaystyle {\ce {<<=>}}} NH+4 + OH−.
In a 1 M ROPAQUE Ultra, about 0.42% of the ammonia is converted to ammonium, equivalent to pH = 11.63 because [NH+4] = 0.0042 M, [OH−] = 0.0042 M, [NH3] = 0.9958 M, and pH = 14 + log10[OH−] = 11.62.
The base ionization constant is

Kb = [NH+4][OH−]/[NH3] = 1.77×10−5.

Saturated Solutions
Like other gases, ammonia exhibits decreasing solubility in solvent liquids as the temperature of the solvent increases.
ROPAQUE Ultra decrease in density as the concentration of dissolved ammonia increases.
At 15.6 °C (60.1 °F), the density of a saturated solution is 0.88 g/ml and contains 35.6% ammonia by mass, 308 grams of ammonia per litre of solution, and has a molarity of approximately 18 mol/L.
At higher temperatures, the molarity of the saturated solution decreases and the density increases.
Upon warming of saturated solutions, ROPAQUE Ultra is released.
ROPAQUE ULTRA EF
ROPAQUE Ultra EF is a non-film forming, acrylic polymer hollow-sphere opaque pigment allowing manufactures to reduce formulation costs without sacrificing properties by being one of the most efficient dry hiding capabilities for interior and exterior coatings.
ROPAQUE Ultra EF is neutralized with ammonia.
ROPAQUE Ultra EF Opaque Polymer expands the boundaries of light scattering
technology, one of the most efficient dry hiding in interior and exterior coatings.

CAS: 1336-21-6
MF: H5NO
MW: 35.05
EINECS: 215-647-6

Synonyms
Ammonium hydroxide solution, 25% NH3, 99.99% trace metals basis;Ammonium hydroxide solution, 20-22% NH3, Environmental;Ammonium hydroxide solution, 28.0-30.0% NH3, ACS;Ammonium hydroxide solution, volumetric, 5.0N in water;1mol/l-Ammonia Solution;Ammonia concentrate;AMMONIUM HYDROXIDE SOLUTION, 1 M IN;AMMONIUM HYDROXIDE, 28% NH3 IN WATER, 99;ammonium hydroxide;1336-21-6;Ammonia aqueous;Ammonia water;Aquammonia;Aqua ammonia;Ammonia, aqua;Household ammonia;Ammonia, monohydrate;Ammonia water 29%;Ammoniumhydroxid;Caswell No. 044;Ammonium hydroxide ((NH4)(OH));SX 1 (ammonia water);ammoniaque;SX 1;NH4OH;HSDB 5125;agua de amoniaco;EINECS 215-647-6;hidroxido de amonio;hydroxyde d'ammonium;EPA Pesticide Chemical Code 005301;DTXSID4020080;CHEBI:18219;EC 215-647-6;E527;ammoniumhydroxide;MFCD00066650;Ammonia, aqueous;Hydroxide, Ammonium;Ammonia water [JAN];UN2672;UN3318;NH(4)OH;ammonia hydrate;water ammonia;ammonium hydoxide;ammonium hydroxid;ammonium hyroxide;amonium hydroxide;ammonium hydorxide;amrnonium hydroxide;NH3 water;water NH3;UN2073;Ammonia water (TN);Ammonium aqueous (28% or less NH3);AMINE HYDRATE;Ammonium hydroxide (28% or less ammonia);Ammonia water (JP17);DTXCID8080;NH3 H2O;NH3-H2O;NH3.H2O;Ammonium hydroxide, 25% NH3;AMMONIUM HYDROXIDE (II)
;Ammonia (ammonium hydroxide) 28% by weight or more NH3;VHUUQVKOLVNVRT-UHFFFAOYSA-N;AKOS015903971;AKOS030228272;NS00075653;C01358;D04594;J-006420

Additionally,this non-film-forming synthetic pigment is specially engineered to improve the economics ofwaterborne coatings while maintaining coating performance.
ROPAQUE Ultra EF is a hollow-sphere polymeric pigment that allows
paint manufacturers to reduce the raw material cost of their formulations with little to no
performance penalties.
products in the ROPAQUE Ultra EF product family.
ROPAQUE Ultra EF is neutralized with ammonia, and ROPAQUE Ultra EF is neutralized with sodium hydroxide.
In addition to offering efficient dry hiding, ROPAQUE Ultra EF offers wide
range benefits in interior and exterior paint formulations.

ROPAQUE Ultra EF is an ammonia-free, holospheric, opaque polymeric pigment. Used in interior and exterior coatings.
Offers increased light scattering efficiency.
ROPAQUE Ultra EF very good opacity.
ROPAQUE Ultra EF allows the manufacturers to reduce the raw material cost of their formulations.
ROPAQUE Ultra EF is a colorless, liquid solution with a characteristic and pungent odor.
ROPAQUE Ultra EF is ammonia combined with water.
ROPAQUE Ultra EF is a compound consisting of nitrogen and hydrogen. Both ammonia and ammonium hydroxide are very common compounds, found naturally in the environment (in air, water, and soil) and in all plants and animals, including humans.
ROPAQUE Ultra EF is a source of nitrogen, an essential element for plants and animals.
ROPAQUE Ultra EF is also produced by the human body – by our organs and tissues and by beneficial bacteria living in our intestines.

ROPAQUE Ultra EF plays an important role in protein synthesis in the human body.
In brief summary, all living things need proteins, which are comprised of some 20 different amino acids.
While plants and microorganisms can synthesize most amino acids from the nitrogen in the atmosphere, animals cannot.
For humans, some amino acids cannot be synthesized at all and must be consumed as intact amino acids.
Other amino acids, however, can be synthesized by microorganisms in the gastrointestinal tract with the help of ammonia ions.
Thus, ROPAQUE Ultra EF is a key player in the nitrogen cycle and in protein synthesis.
ROPAQUE Ultra EF also helps maintain the body's pH balance.
ROPAQUE Ultra EF ,NH40H, is a hydrate of anunonia and exists in crystalline form at -79°C.

Normally, ROPAQUE Ultra EF is only found in an aqueous solution also known as aquaanunonia and anunonia water.
ROPAQUE Ultra EF is prepared by dissolving NH3 inH20. Reagent grade anunonium hydroxide contains from 28 to 30% NH3 at 15.6 °C.
Industrial sales specify the concentration of NH3 in solution in terms of specific gravity.
Common concentrations are 20 °Be, which would bea concentration of 17.8% NH3 (specific gravity 0.933) and 26 °Be (specific gravity 0.897), or a concentration of 29.4% NH3.
ROPAQUE Ultra EF is an excellent medium for the reaction of NH3 (which becomes the NH4 radical in solution) with other compounds for the preparation of anunonium salts and other nitrogen-containing chemicals.
ROPAQUE Ultra EF is an ingredientin deodorants, etching compounds, and cleaning and bleaching materials.
ROPAQUE Ultra EF, as aqua ammonia, finds wide use as a neutralizing agent,because it is inexpensive and strongly alkaline.

Advantages
• No ammonia added resulting in a low odor profile
• Increased light scattering efficiency while maintaining paint performance
• Greater cost savings while providing equal hiding

ROPAQUE Ultra EF Chemical Properties
Melting point: -77°C
Boiling point: 36°C
Density: 0.91 g/mL at 20 °C
Vapor density: 1.2 (vs air)
Vapor pressure: 115 mmHg at 20 °C for 29% solution
Storage temp.: 2-8°C
Solubility: Water (Soluble)
Form: Liquid, Single Sub-Boiling Quartz Distillation
pka: 9.3(at 25℃)
Color: Colorless
Specific Gravity: approximate 0.96 (10%, 15℃)
PH: 10.09(1 mM solution);10.61(10 mM solution);11.12(100 mM solution);
Odor: Strong pungent ammonia odor detectable at 17 ppm
Explosive limit: 27%
Water Solubility: Miscible with water.
λmax λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01
Merck: 14,494
BRN: 3587154
Stability: Stable. Incompatible with copper, copper alloys, acids, galvanised iron, zinc, aluminium, bronze, dimethyl sulphate, mercury, alkali metals.
InChIKey: VHUUQVKOLVNVRT-UHFFFAOYSA-N
CAS DataBase Reference: 1336-21-6(CAS DataBase Reference)
EPA Substance Registry System: ROPAQUE Ultra EF (1336-21-6)

ROPAQUE Ultra EF exists only in the form of an aqueous solution.
ROPAQUE Ultra EF is prepared by dissolving NH3 in H2O and usually is referred to in industrial trade as aqua ammonia.
For industrial procurements, the concentration of NH3 in solution is normally specified in terms of the specific gravity (degrees Baum′e, °Be).
Common concentrations are 20 °Be and 26 °Be.
The former is equivalent to a sp gr of 0.933, or a concentration of about 17.8% NH3 in solution; the latter is equivalent to a sp gr of 0.897, or a concentration of about 29.4% NH3.
These figures apply at a temperature of 60 °F (15.6 °C).
Reagent grade NH4OH usually contains approximately 58% NH4OH (from 28 to 30% NH3 in solution).

Uses
ROPAQUE Ultra EF is widely utilized as a leavening agent or acidity regulator in food production.
ROPAQUE Ultra EF serves as a precursor to some alkyl amines and is also used in the tobacco industry for flavor enhancement and as a processing aid.
During furniture making, ROPAQUE Ultra EF combines with tannic acid and is used to darken or stain wood by making it iron salts.
In chemical laboratories, ROPAQUE Ultra EF used for qualitative inorganic analysis, as a complexant and as a base.
ROPAQUE Ultra EF is used to clean gold, silve, and platinum jewelry.
ROPAQUE Ultra EF is an active component of Tollens' reagent (consisting of a solution of silver nitrate and ammonia) and is used to determine the presence of aldehyde or alpha-hydroxy ketone functional groups.

ROPAQUE Ultra EF is used as a cleaning agent and sanitizer in many household and industrial cleaners.
ROPAQUE Ultra EF is also used in the manufacture of products such as fertilizer, plastic, rayon and rubber.
ROPAQUE Ultra EF is corrosive to aluminum alloys, copper, copper alloys, and galvanized surfaces.
ROPAQUE Ultra EF is an excellent acid neutralizer.
ROPAQUE Ultra EF is an alkaline that is a clear, colorless solu- tion of ammonia which is used as a leavening agent, a ph control agent, and a surface finishing agent.
ROPAQUE Ultra EF is used in baked goods, cheese, puddings, processed fruits, and in the production of caramels.

Health Hazard
ROPAQUE Ultra EF are alkaline solutions, meaning they have high pH level.
As a result, ROPAQUE Ultra EF is a severe eye, skin, and respiratory tract irritant, and readily burns tissue with which it comes in contact.
Splashes to the eye may be serious, as contact may cause severe burns, irritation pain and possibly blindness.
Direct contact with skin may cause severe burns if the chemical is not quickly rinsed away with copious amounts of water.
Inhaling mists of ROPAQUE Ultra EF may result in irritation of the nose and throat with symptoms including burning, coughing, choking and pain.

Inhaling concentrated mist may result in pulmonary edema and shock.
Ingesting ROPAQUE Ultra EF may cause pain and burns of the esophagus and gastrointestinal tract.
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death.
Contact with molten substance may cause severe burns to skin and eyes.
Avoid any skin contact.
Effects of contact or inhalation may be delayed.
Fire may produce irritating, corrosive and/or toxic gases.
Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Rosa canina
rosa canina l. bud extract; dog-brier bud extract; extract of the buds of rosa canina, rosaceae; rosa ciliatosepala bud extract; rosa corymbifera bud extract;rose bud extract CAS NO:84696-47-9
ROSA EXTRACT
ROSE FLOWER OIL, N° CAS : 8007-01-0 - Huile de rose. Autre langue : Rose oil, Nom INCI : ROSE FLOWER OIL. Classification : Huile essentielle. Ses fonctions (INCI) : Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit
ROSE FLOWER OIL
ROSE FLOWER OIL, N° CAS : 8007-01-0 - Huile de rose. Autre langue : Rose oil. Nom INCI : ROSE FLOWER OIL. Classification : Huile essentielle. Ses fonctions (INCI). Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit
ROSELLE (HIBISCUS) FLOWER EXTRACT

Roselle (Hibiscus) Flower Extract, derived from the Hibiscus sabdariffa plant, is known for its rich antioxidant content, anti-inflammatory properties, and ability to promote skin hydration and health.
Roselle (Hibiscus) Flower Extract is widely recognized for its use in skincare, hair care, and wellness formulations, where it helps to protect against oxidative stress, support collagen production, and improve overall skin tone and texture.
This versatile extract offers both cosmetic and therapeutic benefits, making it a popular ingredient in anti-aging products, hair conditioners, and immune-boosting supplements.

CAS Number: 84775-96-2
EC Number: 283-920-7

Synonyms: Hibiscus Flower Extract, Roselle Extract, Hibiscus sabdariffa Flower Extract, Roselle Herbal Extract, Hibiscus Phytocomplex, Roselle Bioactive Extract, Hibiscus Active, Roselle Sabdariffa Extract, Hibiscus sabdariffa Extract, Roselle Flower Phytocomplex



APPLICATIONS


Roselle (Hibiscus) Flower Extract is extensively used in anti-aging skincare products for its antioxidant properties, which help to neutralize free radicals, reduce signs of aging, and promote collagen production for firmer skin.
Roselle (Hibiscus) Flower Extract is favored in the formulation of moisturizing creams and lotions, where it helps to hydrate the skin, improve elasticity, and protect against environmental stressors.
Roselle (Hibiscus) Flower Extract is utilized in the development of brightening serums, where it helps to even out skin tone, lighten dark spots, and improve skin radiance.

Roselle (Hibiscus) Flower Extract is widely used in hair care products such as conditioners and hair masks, where it helps to strengthen hair strands, reduce hair breakage, and promote shine.
Roselle (Hibiscus) Flower Extract is employed in the creation of scalp treatments for promoting hair growth, reducing dandruff, and soothing irritated or dry scalps.
Roselle (Hibiscus) Flower Extract is essential in the development of body scrubs and exfoliants, where its natural acids help to gently exfoliate dead skin cells and reveal smoother, softer skin.

Roselle (Hibiscus) Flower Extract is utilized in the production of wellness supplements aimed at boosting immune health, where its high vitamin C content helps to support the body’s natural defenses.
Roselle (Hibiscus) Flower Extract is a key ingredient in detox beverages and teas, where it helps to cleanse the body of toxins, support digestion, and promote healthy liver function.
Roselle (Hibiscus) Flower Extract is used in the development of anti-inflammatory supplements, offering benefits for reducing inflammation and supporting joint health.

Roselle (Hibiscus) Flower Extract is applied in the formulation of eye creams and serums, where its antioxidant and moisturizing properties help to reduce puffiness, dark circles, and fine lines around the eyes.
Roselle (Hibiscus) Flower Extract is employed in the creation of lip balms and treatments, providing hydration and antioxidant protection for dry, chapped lips.
Roselle (Hibiscus) Flower Extract is used in natural remedies for managing high blood pressure, where it helps to promote healthy circulation and reduce hypertension.

Roselle (Hibiscus) Flower Extract is widely utilized in skin-soothing formulations for treating conditions such as eczema and psoriasis, where it provides anti-inflammatory relief and improves skin hydration.
Roselle (Hibiscus) Flower Extract is a key component in wellness products that support heart health, where its antioxidants help to reduce oxidative stress and protect against cardiovascular disease.
Roselle (Hibiscus) Flower Extract is used in products designed to promote skin cell turnover, offering benefits for accelerating healing and improving the overall texture and clarity of the skin.

Roselle (Hibiscus) Flower Extract is employed in the formulation of natural toners and astringents, where it helps to tighten pores, balance oil production, and refine the skin’s texture.
Roselle (Hibiscus) Flower Extract is applied in the development of soothing bath oils and soaks, offering benefits for hydrating the skin, reducing inflammation, and promoting relaxation.
Roselle (Hibiscus) Flower Extract is utilized in face masks and beauty treatments aimed at revitalizing the skin and improving its radiance and firmness.

Roselle (Hibiscus) Flower Extract is found in wellness teas and infusions designed to promote digestive health, where it helps to soothe the stomach, reduce bloating, and support healthy digestion.
Roselle (Hibiscus) Flower Extract is used in products designed to reduce cholesterol levels, where it helps to promote heart health by improving lipid profiles and reducing oxidative damage in blood vessels.
Roselle (Hibiscus) Flower Extract is a key ingredient in sleep-support supplements, where its calming and relaxing properties help to promote restful sleep and reduce insomnia.



DESCRIPTION


Roselle (Hibiscus) Flower Extract, derived from the Hibiscus sabdariffa plant, is known for its rich antioxidant content, anti-inflammatory properties, and ability to promote skin hydration and health.
Roselle (Hibiscus) Flower Extract is widely recognized for its use in skincare, hair care, and wellness formulations, where it helps to protect against oxidative stress, support collagen production, and improve overall skin tone and texture.

Roselle (Hibiscus) Flower Extract offers additional benefits such as reducing signs of aging, improving skin elasticity, and promoting overall skin health.
Roselle (Hibiscus) Flower Extract is often incorporated into formulations designed to moisturize, protect, and revitalize the skin, making it an ideal choice for anti-aging and hydrating products.
Roselle (Hibiscus) Flower Extract is recognized for its ability to promote hair health by strengthening hair strands, reducing dandruff, and encouraging healthy hair growth.

Roselle (Hibiscus) Flower Extract is commonly used in both traditional and modern wellness formulations, providing a reliable solution for supporting heart health, boosting immune function, and promoting radiant skin.
Roselle (Hibiscus) Flower Extract is valued for its ability to reduce inflammation, promote collagen synthesis, and improve skin hydration, making it a popular ingredient in skincare and hair care products.
Roselle (Hibiscus) Flower Extract is a versatile ingredient that can be used in a variety of products, including face creams, serums, hair conditioners, teas, and wellness supplements.

Roselle (Hibiscus) Flower Extract is an ideal choice for products targeting anti-aging, hydration, and immune support, providing natural and effective care for these concerns.
Roselle (Hibiscus) Flower Extract is known for its compatibility with other hydrating and antioxidant-rich ingredients, making it easy to integrate into multi-functional formulations.
Roselle (Hibiscus) Flower Extract is often chosen for formulations requiring a balance between hydration, antioxidant protection, and skin-brightening effects, ensuring comprehensive health and beauty benefits.

Roselle (Hibiscus) Flower Extract enhances the overall effectiveness of skincare, hair care, and wellness products by providing natural support for hydration, collagen production, and antioxidant protection.
Roselle (Hibiscus) Flower Extract is a reliable ingredient for creating products that offer noticeable improvements in skin texture, hydration, and overall radiance.
Roselle (Hibiscus) Flower Extract is an essential component in innovative wellness and beauty products known for their performance, safety, and ability to support skin health, hair vitality, and immune function.



PROPERTIES


Chemical Formula: N/A (Natural extract)
Common Name: Roselle Flower Extract (Hibiscus sabdariffa Flower Extract)
Molecular Structure:
Appearance: Dark red to brown powder or liquid extract
Density: Approx. 1.00-1.05 g/cm³ (for powder)
Melting Point: N/A (powder form)
Solubility: Soluble in water and ethanol; insoluble in oils
Flash Point: >100°C (for powder)
Reactivity: Stable under normal conditions; no known reactivity issues
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store between 15-25°C in a cool, dry place
Vapor Pressure: Low (for liquid extract)



FIRST AID


Inhalation:
If Roselle (Hibiscus) Flower Extract is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Wash the affected area with soap and water.
If skin irritation persists, seek medical attention.

Eye Contact:
In case of eye contact, flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
If Roselle (Hibiscus) Flower Extract is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles if handling large quantities.
Use in a well-ventilated area to avoid inhalation of dust.

Ventilation:
Ensure adequate ventilation when handling large amounts of Roselle (Hibiscus) Flower Extract to control airborne concentrations below occupational exposure limits.

Avoidance:
Avoid direct contact with eyes and prolonged skin contact.
Do not eat, drink, or smoke while handling Roselle (Hibiscus) Flower Extract.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Contain spills to prevent further release and minimize exposure.
Absorb with inert material (e.g., sand, vermiculite) and collect for disposal.
Dispose of in accordance with local regulations.

Storage:
Store Roselle (Hibiscus) Flower Extract in a cool, dry, well-ventilated area away from incompatible materials (see SDS for specific details).
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and ignition sources.

Handling Cautions:
Avoid inhalation of dust and direct contact with skin and eyes.
Use explosion-proof equipment in areas where dust or vapors may be present.



ROSEMARY EXTRACT

Rosemary Extract seems to increase blood circulation when applied to the scalp, which might help hair follicles grow.
Rosemary extract might also help protect the skin from sun damage.


CAS Number Extract of rosemary: 84604-14-8
Carnosic acid: 3650-09-7
Carnosol: 5957-80-2
Chemical formula Carnosic acid: C20H28O4
Carnosol: C20H26O4



Carnosic acid: 4a(2H)-Phenanthrenecarboxylic acid, 1,3,4,9,10,10ahexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR-trans)- Carnosol: 2H-9,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a- hexahydro-5,6-dihydroxy-1,1-dimethyl-7(1-methylethyl), (4aR- (4aα,9α,10aβ))-



Rosemary Extract is a well-known culinary herb.
Rosemary Extract is applied to the skin helps strengthen the capillaries and has a rejuvenating effect.
Recent research is now revealing even more benefits attached to this remarkable herb, including Rosemary Extract's ability to help prevent cancer and age-related skin damage, boost the functioning of the liver and act as a mild diuretic to help reduce swelling.


Rosemary (Rosmarinus officinalis) is a small evergreen shrub belonging to the sage of the Lamiaceae family.
Rosemary Extract is native to Europe, North Africa and the Mediterranean coast.
In recent years, Rosemary Extract has been used in Yunnan, Guangxi, Hainan, Hunan, Sichuan, Guizhou, Fujian and other provinces Both are planted.


Rosemary is a versatile economic crop, which can extract antioxidants and rosemary essential oil.
The main components of antioxidants are diterpenoids, flavonoids, triterpenes and other compounds with antioxidant functions.
Rosemary Extract seems to increase blood circulation when applied to the scalp, which might help hair follicles grow.


Rosemary extract might also help protect the skin from sun damage.
Rosemary Extract is beige to light brown powder.
Rosemary leaf is a shrub with fragrant, evergreen, needle-like leaves and white, pink, purple, or blue flowers, native to the Mediterranean region.


Until 2017, Rosemary Extract was known by the scientific name Rosmarinus Officinalis.
The plant flowers in spring and summer in temperate climates, but the plants can be in constant bloom in warm climates; flowers are white, pink, purple or deep blue.


Rosemary Extract also has a tendency to flower outside its normal flowering season; it has been known to flower as late as early
Rosemary extract consists of phenolic diterpenes, carnosic acid and carnosol as principal antioxidants.
Other components present include triterpenes and triterpenic acids.


Rosemary Extract is obtained from ground dried leaves of Rosmarinus officinalis L using food-grade solvents, namely, acetone or ethanol.
Solvent extraction is followed by filtration, solvent removal, drying and sieving to obtain a fine powder.
Additional concentration and/or precipitation steps followed by deodorisation, decolourisation and standardisation using diluents and carriers of food grade quality may be included to produce the final product.


Rosemary Extract of commerce can be standardized to a total carnosic acid and carnosol content up to 33%.
Rosemary Extract is suitable as a natural antioxidant in foods and cosmetic/toiletry products.
Rosemary Extract has a number of more wide-ranging uses which are becoming well documented.


Specific inclusion levels for preservative uses are not widely published.
Rosemary Extract is a natural product and as such it would generally be expected to require higher inclusion levels than synthetics to be effective.
Rosemary Extract antioxidant is a thick, viscous liquid, and due to the colour of the ingredient it may discolour your soaps.


Rosemary Extract is a powerful antioxidant and anti-inflammatory agent that prevents carcinogens from binding to DNA, and stimulates liver detoxification of carcinogens.
This is a powerful, standardized lipid fat or oil soluble antioxidant, Rosemary Extract, used at only 0.1 percent.


Recent studies show that Rosemary Extract and its constituents, carnosol and ursollic acid, enhance activity of enzymes that can detoxify carcinogens.
Rosemary Extract is a natural product frequently used in the food industry to prevent spoilage of foods containing fat and has not shown evidence of accumulating in body tissue.


Like other antioxidants, Rosemary Extract inhibits and fights free radicals.
Rosemary Extract is an aromatic member of the mint family native to the Mediterranean region where it is utilized as a treasured culinary spice with wellness properties.


This flowering evergreen produces thin, needle-like leaves and is commonly cultivated and easily grown in many household gardens.
Rosemary Extract has a familiar and distinctive piney and fresh scent.
Rosemary Extract has been revered for its bounty of healthful benefits for ages.


Rosemary Extract contains antioxidants and has both carminative and bitter properties.
Rosemary Extract also has an affinity for the brain and supports overall cognitive health.
Rosemary Extract is made in small batches from fresh, organic rosemary leaves at our extract facility in Eugene, Oregon.


Rosemary Extract is highly aromatic and somewhat bitter and can be taken on the tongue or in water or juice.
Rosemary Extract can be combined with gotu kola extract, hawthorn extract, or oats extract.
This tincture pairs well with teas such as dawn chorus tea.


Rosemary Extract is CO2 extracted from the bark of the rosemary plant.
Rosemary Extract is a yellow-green to brown viscous oil in a sunflower seed carrier oil.
Rosemary Extract is a natural, organic antioxidant for cosmetics such as massage oil.


Rosemary Extract is a special extract of rosemary leaves with strong antioxidant properties.
If this end product, Rosemary Extract, contains a lot of oxidation sensitive substances, for example borage oil or other polyunsaturated oil, sit on the high side.


Simply mix Rosemary Extract with the oil, or melt it together with fats and waxes.
Try to keep Rosemary Extract the temperature as low as possible.
Rosemary Extract is a natural extract also referred to by the botanical name Rosmarinus officinalis L. Rosemary extract is CO2 extracted from leaves of

Rosmarinus officinalis and contains a minimum of 5% Carnosic Acid, the active component and antioxidant of this material, also present in sage.
Rosemary Extract is a yellow-green to brown powder supplied in the carrier sunflower seed oil, carrying an overall dark appearance.
Rosemary Extract coming from the lovely herb, rosemary.


Rosemary Extract contains lots of chemicals, including flavonoids, phenolic acids, and diterpenes.
Rosemary Extract's main active is rosmarinic acid, a potent antioxidant, and anti-inflammatory.
Rosemary Extract has also anti-bacterial, astringent and toning properties.


The leaves contain a small amount of essential oil (1-2%) with fragrant components, so if you are allergic to fragrance, Rosemary Extract might be better to avoid it.
Rosemary Extract is brown viscous liquid with slight rosemary aroma.


Rosemary Extract is Alcohol Extraction from the leaf.
Globally, Rosemary is grown between 9°C to 28°C with the pH of soil maintained at 4.5 to 8.7 with a rainfall of 0.3 to 2.7 meters.
Rosemary Extract is rich in anti-oxidants and is a useful addition to personal care products.


When used in conjunction with Vitamin E it rejuvenates the Vitamin E, increasing Rosemary Extract’s potency.
Rosemary (Rosmarinus officinalis) is a fragrant herb with evergreen, needle-like leaves, and white, pink, purple, or blue flowers.
Rosemary has been used in culinary applications since ancient times and reports on its antioxidant activity date back to the 1950s.


Rosemary can be grown in a wide range of environmental conditions. Rosemary leaves contain two acids named Ursolic acid and Carnosic acid.
Both the acids exhibit anti-bacterial, anti-cancer, anti-oxidative, and anti-inflammatory properties.



USES and APPLICATIONS of ROSEMARY EXTRACT:
Uses of Rosemary Extract: Olive Oil, Dressing, Sauces
Rosemary Extract is used food additive ingredients, Various animal and vegetable oils, animal feed, meat products, seafood, flour, sauces, seasonings, baked goods, fried products, natural pigments, flavors.


Rosemary Extract is used personal care ingredients, Cosmetics, perfumes, soaps, air fresheners, insect repellents.
Rosemary extract has high content minerals, vitamins and trace elements which provide tonic, soothing and anti-inflammatory properties for the skin and hair.


Rosemary Extract is rich in antioxidant factors, which provide protection against external factors that lead to premature aging of the epidermis.
Rosemary Extract is ideal for facial toners, cleansing or anti-aging lotions and also for hair care products.
Rosemary Extract contains a powerful antioxidant, carnosic acid, as well as astringent properties, making it a popular choice in personal care products to help maintain skin elasticity and improve skin tone.


Rosemary extract can also enhance blood circulation to the scalp, making it a popular addition to hair care products to aid in healthy hair growth and nourishment.
Application of Rosemary Extract: General purpose, suits most cosmetic applications; Hair products (shampoo & conditioners); Cleansers (gel & creams); Bath gel, shower gel, bubble bath; Creams, lotions, body butters (oil & water emulsions for body & face); Shave products.


Rosemary Extract is suitable for: Face, Body and Hair products.
Rosemary Extract contains powerful antioxidants as well as astringent properties, making it a popular choice in personal care products to help maintain skin elasticity and improve skin tone.


Applications of Rosemary Extract: Food additive ingredients, Personal care ingredients and Pharmaceutical raw materials.
Culinary use: Rosemary extract has been shown to improve the shelf life and heat stability of omega 3-rich oils which are prone to rancidity.
Phytochemicals: Rosemary extract, specifically the type mainly consisting of carnosic acid and carnosol, is approved as a food antioxidant preservative in several countries.


The E number of Rosemary Extract is E392.
Rosemary Extract has the characteristics of high efficiency and safety, and is widely used in cosmetics, perfume, soap, air freshener, insect repellent, medicine, animal fat, animal feed, meat, seafood, flour, seasoning sauce, seasoning, Baked foods, fried products, natural pigments, flavors, biological pesticides, tobacco and other fields have brought a lot of convenience to production and life.


In Europe, Rosemary Extract has a long history as a edible spice and has been used in cosmetics, food and medicine.
Food industry uses of Rosemary Extract: Antioxidant, antibacterial;
Medical and healthcare industry uses of Rosemary Extract: Protect the liver from damage, refresh, enhance memory, improve tension and insomnia, anti-depressive.


In the field of cosmetics uses of Rosemary Extract: Rosemary extract can enhance skin elasticity and delay aging; accelerate blood circulation in the scalp.
Rosemary (Rosmarinus officinalis) is an herb native to the Mediterranean region.
The leaf and Rosemary Extract's oil are commonly used in food and also to make medicine.


People commonly use Rosemary Extract for memory, indigestion, fatigue, hair loss, and many other purposes, but there is no good scientific evidence to support most of these uses.
Some people claim that Rosemary Extract can help reduce muscle pain, boost the immune system, and improve memory.


However, Rosemary Extract can interact with some medications.
Rosemary is an ingredient that adds a fragrant savory note to dishes.
Rosemary Extract is a fragrant evergreen herb native to the Mediterranean.


Rosemary Extract is used as a culinary condiment, to make bodily perfumes, and for its potential health benefits.
Rosemary Extract is a member of the mint family Lamiaceae, along with many other herbs, such as oregano, thyme, basil, and lavender.
The herb not only tastes good in culinary dishes, such as rosemary chicken and lamb, but it is also a good source of iron, calcium, and vitamin B-6.


Rosemary Extract is typically prepared as a whole dried herb or a dried powdered extract, while teas and liquid extracts are made from fresh or dried leaves.
The herb has been hailed since ancient times for Rosemary Extract's medicinal properties.


Rosemary Extract was traditionally used to help alleviate muscle pain, improve memory, boost the immune and circulatory system, and promote hair growth.
As an extract, Rosemary Extract can be used as a natural diuretic, tonic, decongestant, and a tissue toner and firmer.
Rosemary Extract is used internally as a traditional herbal medicine for the treatment of dyspepsia and crampy gastrointestinal complaints.


Externally, Rosemary Extract is used to treat mild muscle and joint pain and mild circulatory disorders.
In folk medicine, Rosemary Extract is used for general digestive problems, headaches and migraines.
Rosemary Extract has antioxidant properties, which is why it is used as an antioxidant in the food industry, especially for stabilising fat and oils, sausage and meat products or seasonings and sauces.


Rosemary Extract is also suitable as an antioxidant for stabilizing food supplements.
Due to the carnosic acid found in the extract, Rosemary Extract has antioxidant properties.
When Rosemary Extract is applied to the skin, oxidative changes in skin surface lipids can be reduced by the extract.


Therefore, Rosemary Extract is suitable as an ingredient in cosmetic skin care products, especially in anti-aging products.
Rosemary Extract can be used as an antioxidant in oily, alcohol or oil-based oily cosmetics and perfumes.
Use about 0.1-0.5% in the final product.


Rosemary Extract can be used in oil or fat-based cosmetics such as ointments, oil perfumes and massage oil.
In emulsions Rosemary Extract can be added to the fat phase.
Rosemary Extract can be used in alcoholic products as long as the dosage is low.


Rosemary extract is less potent than rosemary essential oil and used favorably in cooking.
Rosemary Extract may be taken internally as a source of antioxidants in addition to a range of topical applications throughout the personal-care and cosmetic industries such as moisturizing creams, facial ointments, skincare serums, and haircare products.


Rosemary Extract is less aromatic and may be taken internally or used in personal care as a source of antioxidants.
Rosemary Extract contains a minimum of 5% Carnosic Acid, the active component and antioxidant of this material found in both rosemary and sage.
Rosemary Extract has a number of topical applications in the cosmetic industry such as moisturizing creams, facial ointments, and haircare products.


The recommended amount to add to cosmetic products in order to prevent the oxidation of carrier and essential oils and to inhibit an aromatic effect on Rosemary Extract is 0.3 – 0.6% of the total.
Rosemary Extract also adds additional antioxidant benefits to your products.


Rosemary Extract can have antioxidant benefit for skin, but its aromatic components can cause sensitivity.
However, in most skin care products the amount of Rosemary Extract is unlikely to be a risk, and rosemary extract is much less of a problem for skin than rosemary oil because the extract usually doesn’t contain much, if any, of rosemary oil’s volatile fragrance components.


Research has shown that rosmarinic acid, one of the components in Rosemary Extract, has a calming effect on skin, which may be useful for mitigating several common skin issues.
Rosmarinic acid is an antioxidant, as is caffeic acid, another naturally occurring component of rosemary.


Originally native to the Mediterranean, this aromatic, evergreen shrub can be found all over the world and contains beneficial compounds in every part of the plant.
Rosemary Extracttherapeutic properties made it a popular treatment in folk medicine to relieve muscle spasms; nowadays, rosemary is more commonly used for its soothing qualities.


Many packaged breakfast foods are, unsurprisingly, filled with preservatives.
Things like granola bars, English muffins, pancake syrup, and cereal are made with ingredients that will eventually spoil, yet they’re intended to stay fresh on the grocery store shelf for weeks, if not months.


Because of this, Rosemary Extract’s not strange to see them contain preservatives like citric acid, sodium sorbate, potassium sorbate, sodium benzoate, sodium nitrite, and sulphur dioxide.
Ultimately, these chemicals keep packaged foods from growing bacteria, spoiling, and discoloring.


Otherwise, Rosemary Extract is used in food also.
In addition to antioxidants rosemary extract also contains several reference volatile that is responsible for its flavor and odor.
While Rosemary Extract’s better for business to keep foods fresh for as long as possible, it has been proven that many of these preservatives can be harmful to the body if consumed in excess or over a long period of time.


However, studies have found that there are certain natural products that actually do the same job as the preservatives, one of them being rosemary extract.
Rosemary Extract is a small evergreen perennial shrub indigenous to European countries bordering the Mediterranean Sea.
Although the entire plant is known to have been used for human applications, Rosemary Extract is the extracts of the dried leaves that have common food and medicinal use.


Rosemary Extract is a rich source of antioxidants and anti-inflammatory compounds, which are thought to help boost the immune system and improve blood circulation.
The benefits of Rosemary extract include relieving headaches, respiratory sicknesses, and upset stomachs, as well as being added to ointment for skin infections, sores, and insect bites.


Rosemary Extract is a fragrant, woody herb often used to season dishes like roast chicken or potatoes.
But Rosemary Extract's potential extends far beyond just being a flavor enhancer.
Rosemary Extract extract is slowly growing in popularity among certain food producers due to its ability to act as a natural preservative.


The antioxidant properties of rosemary extract come from bioactive compounds in the plant known as polyphenols.
Rosemary Extract contains carnosic acid and rosmarinic acid, both of which help delay oxidation of fats and slow down the effectiveness of any microorganisms that cause food to spoil.


These polyphenols were studied by the European Food Safety Authority in 2008, and later, the European Union approved the use of rosemary extract in a number of forms for food preservation.
Rosemary Extract remains an approved food additive in the eyes of the FDA.


Since rosemary extract works so well when it comes to keeping oils from going rancid, it’s often used in items with high fat contents, like sausage or chorizo, or in some condiments like salad dressing.
Rosemary Extract’s also found in packaged granola bars with a high fat content from nuts and oils that are intended to stay fresh for months, like Nature Valley Crisps, Enjoy Life Chewy Bars, and Kellogg’s Special K Nourish bars and bites.


Rosemary Extract can be used as a natural preservative to improve the shelf life of oils prone to rancidity.
These acids are used as food preservatives and also for fighting lethal diseases.
Rosemary Extract is reputed be a highly efficient antioxidant and can be used in cosmetics and skin care products.
Rosemary Extract can also be used to strengthen skin elasticity and assists in slowing the signs of the aging.


-FOOD ANTIOXIDANT uses of Rosemary Extract:
Oxidation is the main cause of food spoilage.
Consequences are: loss of freshness, unpleasant flavors and changes in texture and color.
Several studies have shown that the antioxidant power of rosemary extract is more effective than other conventional antioxidants used in the food industry.
Examples of foods in which rosemary extracts have proven effective: animal fats, vegetable oils, mayonnaise, meats, spices, beverages and animal feed.



FUNCTIONS OF ROSEMARY EXTRACT:
Rosemary Extract has antioxidant and anti-inflammatory effects;
Rosemary Extract helps to strengthen immunity;
Rosemary Extract helps stroke and other neurodegenerative diseases;
Rosemary Extract protects brain cells from free radical damage.



FUNCTION AND APPLICATION OF ROSEMARY EXTRACT:
1. As natural antioxidant, Rosemary Extract's antioxidant activity is higher than VE.
Rosemary Extract is widely used in cosmetics, food, fragrance, perfume, shower gel, shampoo, soap and air fresheners.
2.Rosemary Extract is widely used as a mild sedative and antibacterial agent
3. Rosemary Extract provides protection to the brain cells from the effects of aging process and enhances memory.
4. The biological activity of rosmarinic acid, Rosemary Extract, is described as antibacterial,antiviral,and antioxidative.



FAST FACTS ON ROSEMARY EXTRACT:
Rosemary is a perennial plant (it lives more than 2 years).
The leaves are often used in cooking.
Possible health benefits include improved concentration, digestion, and brain aging.



7 PROVEN USES AND BENEFITS OF ROSEMARY EXTRACT:
Rosemary leaves are used as a flavoring in foods ( You Should Know Lemon oil for flavoring in foods ), such as stuffing and roast lamb, pork, chicken, and turkey.
Rosemary Extract provides antioxidants when ingested by your body.

Rosemary Extract contains Antioxidants that fight free radicals, which many experts believe are responsible for cancer and other diseases.
Some uses of Rosemary Extract include relieving headaches, respiratory sicknesses, and upset stomachs, as well as being added to ointment for skin infections, sores, and insect bites.

Rosemary Extract is often used to help treat indigestion.
Rosemary Extract may also be good for your brain.

Rosemary Extract contains an ingredient called carnosic acid, which can fight off damage by free radicals in the brain.
Rosemary Extract may help prevent brain aging.
The therapeutic ability of Rosemary Extract for the prevention of Alzheimer's shows promise.



HISTORY OF ROSEMARY EXTRACT:
Rosemary is a widely used culinary spice or flavoring agent in foods.
Rosemary was traditionally suggested as growing only in gardens of households where the "mistress" is truly the "master."
Tyler 1987 Historical reports regarding therapeutic use of rosemary plant are available.

Selmi 1967, Zimmermann 1980 The plant has been used in traditional medicine for its astringent, tonic, carminative, antispasmodic, and diaphoretic properties.
Extracts and the volatile oil have been used to promote menstrual flow and as abortifacients.

Tyler 1987 Rosemary extracts are commonly found in cosmetics, and a lotion of the plant has been said to stimulate hair growth and prevent baldness.
(Duke 2002 In the Complete German Commission E Monographs, rosemary leaf is approved for internal use in dyspeptic complaints and for external use as supportive therapy in rheumatic diseases.
Blumenthall 2000 Rosemary, one of the oldest known medicinal herbs, was used centuries ago to enhance mental function and memory.



EXTRACTION PROCESS OF ROSEMARY EXTRACT (HOW TO MAKE):
Extraction Process (How to Make):
Rosemary extracts are prepared by extraction from dried rosemary leaves.
The present opinion refers to production processes using solvent extraction by ethanol, acetone, and/or hexane.



PROPERTIES OF ROSEMARY EXTRACT:
Rosemary contains a number of phytochemicals, including rosmarinic acid, camphor, caffeic acid, ursolic acid, betulinic acid, carnosic acid, and carnosol.



BENEFITS OF ROSEMARY EXTRACT:
Rosemary, a native of the Mediterranean, is an aromatic, evergreen shrub with small, pale blue flowers.
Rosemary Extract is now found growing in most parts of the world.
Rosemary Extract is a popular culinary herb and its therapeutic benefits have been well known since ancient times.

The CO2 extraction method, using fresh rosemary leaf, maintains the integrity of the plant’s bioactive compounds.
Rosemary Extract’s growing popularity as a cosmetic ingredient in recent times is due to its powerful, concentrated antioxidant properties which delays the oxidation of fatty oils.

Even used very sparingly, Rosemary Extract can act as a natural preservative for hand-crafted cosmetics, creams, salves, soaps, shampoos and natural household cleaners.
The (re)discovery of nature’s antioxidants allows consumers (and manufacturers of natural products) to give their beauty products an extended shelf-life without resorting to synthetic chemicals.

Rosemary extract can be blended with vegetable carrier oils, any oil-based products or, used with an emulsifier, it can delay the oxidation of water-soluble compounds.
In addition to being a valued antioxidant, rosemary extract has antimicrobial, anti-inflammatory and antimicrobial properties.



PROPERTIES OF ROSEMARY EXTRACT:
Rosemary Extract is a dark brown, viscous liquid at room temperature.
Rosemary Extract contains about 14% substances with an antioxidant effect.

Rosemary Extract has a distinctive rosemary scent.
Of course, this smell influences the smell of the product, including perfumes.
The sunflower seeds and Rosemary Extract used are organically grown.

Please note: when making this extract, special attention was paid to its antioxidant properties.
Other rosemary extracts do not necessarily have this effect or to a much lesser extent.



SCIENCE OF ROSEMARY EXTRACT:
Rosemary extract gets its anti-inflammatory properties from a range of bioactive components including carsonic acid, ursolic acid, and rosmarinic acid.
Rosemary Extract works to inhibit the causes of inflammation, instead boosting microcirculation beneath the skin to keep it strong and healthy while preventing any dryness, scaliness, or itching.

Rosemary extract is well-known for its high antioxidant content, which mainly comes from polyphenols – good at scavenging free radicals caused by environmental and lifestyle factors, such as prolonged sun exposure and pollution.
Rosemary Extract has also been shown to protect cell DNA from even forming free radicals to begin with, which helps the cells to continue producing a sufficient amount of collagen and can prevent the aging of skin and hair.



SUSTAINABILITY OF ROSEMARY EXTRACT:
Rosemary Extract is made by extracting organically grown rosemary leaves with natural carbon dioxide.
Rosemary Extract thus obtained is strengthened with organic sunflower oil.
Rosemary Extract is completely biodegradable in the environment.



PHYSICAL and CHEMICAL PROPERTIES of ROSEMARY EXTRACT:
Product name: Rosemary Extract
Botanical name: Rosmarinus officinalis
C.A.S. number Extract of rosemary: 84604-14-8
Carnosic acid: 3650-09-7
Carnosol: 5957-80-2
Chemical formula Carnosic acid: C20H28O4
Carnosol: C20H26O4
Formula weight Carnosic acid: 332.43
Carnosol: 330.42



FIRST AID MEASURES of ROSEMARY EXTRACT:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ROSEMARY EXTRACT:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ROSEMARY EXTRACT:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ROSEMARY EXTRACT:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ROSEMARY EXTRACT:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Store at Room Temperature.
Light sensitive



STABILITY and REACTIVITY of ROSEMARY EXTRACT:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available


ROSEMARY OIL
Rosemary oil is a colorless or pale-yellow liquid with varying physical–chemical constants, depending on the source.
In hair conditioners, mouth rinses, fragrances; flavoring agent in foods.
Extractives and their physically modified derivatives.

CAS: 8000-25-7
EINECS: 290-140-0

Rosemary oil is a popular essential oil derived from the leaves of the Rosmarinus officinalis plant.
Rosemary oil has a wide range of uses, from aromatherapy to culinary applications, and it has been used in traditional medicine for centuries. Rosemary oil is known for its calming, stimulating, and anti-inflammatory properties.
In recent years, scientific research has revealed the many potential benefits of Rosemary oil, including its ability to improve cognitive performance and reduce inflammation.
This paper will discuss the synthesis method, scientific research applications, mechanism of action, biochemical and physiological effects, advantages and limitations for lab experiments, and future directions of rosemary oil.

Rosemary oil Chemical Properties
Boiling point: 176 °C
Alpha: aD25 -5 to +10°
Density: 0.908 g/mL at 25 °C
FEMA: 2992 | ROSEMARY OIL (ROSEMARINUS OFFICINALIS L.)
Refractive index: n20/D 1.468
Fp: 121 °F
Solubility: Chloroform (Slightly), Methanol (Slightly)
Form: Oil
Color: Colourless to Yellow
Odor: at 100.00 %. rosemary
Odor Type: herbal
Optical activity: [α]20/D +1.2°, neat
EPA Substance Registry System: Rosemary oil (8000-25-7)

Rosemary oil is obtained by steam distillation of the twigs and flowering tops of Rosmarinus officinalis L. (Lamiaceae).
Rosemary oil is an almost colorless to pale yellow liquid with a characteristic, refreshing, pleasant odor.
Rosemary oil is usually a trace constituent in North African oils (0–0.4%), but occurs in Spanish oils in quantities between 0.7% and 2.5%.
The main producers of rosemary oil are Tunisia,Morocco, and Spain, with total ~120 t annually.
Rosemary oil is used widely in perfumery and in large amounts for perfuming bath foams, shampoos, and hair tonics.

Obtained by steam distillation with yields of approximately 0.5 to 1.2% from the fresh, flowering tops.
Rosemary oil has a characteristic odor of rosemary and a warm, camphoraceous taste.
Spanish rosemary essential oil has the largest production.
Rosemary oleoresin is a purified extract of rosemary from which nearly all of the characteristic rosemary odor and flavor have been removed, leaving a faint note of cooked herbs.

Rosemary Oil is a pale yellow or almost colorless, mobile liquid of strong, fresh, woodyherbaceous, somewhat minty-forestlike odor.
The “high” fresh notes vanish quickly, yielding to a clean, woodybalsamic bodynote which tones out in a dryherbaceous, but very pleasant and tenacious, bitter-sweet note.
There is considerable difference in the odor of the various types of rosemary oil.
Apart from a very high amount of monoterpenes, rosemary oil contains a significant amount of Borneol, a crystalline terpene alcohol, but this is also the main oxygenated component of the oil.
Rosemary oil is, accordingly, not very soluble in diluted alcohol (below 80%), but it finds extensive use in perfumery for citrus colognes, lavender waters, fougères, pine needle fragrances, Oriental perfumes (it blends excellently with olibanum and spice oils), in roomdeodorants, household sprays, insecticides, disinfectants, etc.

Uses
Rosemary oil is credited with anti-septic properties, it is also used for masking odor and providing fragrance.
Rosemary oil is considered beneficial for acne, dermatitis, and eczema.
Some reports indicate that rosemary oil may stimulate fibroblast growth with a possible increase in epidermal cell turnover.
This would make Rosemary oil useful in products for aging and mature skin.
Rosemary oil, obtained through distillation of the herb’s flowering tops, is superior to that obtained through distillation of the stems and leaves.
The latter process, however, is more common among the commercial oils.
Rosemary Oil is an essential oil with antibacterial properties.

Synthesis Method
Rosemary oil is extracted from the leaves of the Rosmarinus officinalis plant.
Steam distillation is the most common method used to extract the essential oil from the plant material.
The essential oil is then separated from the water and collected as a liquid.
Rosemary oil is then filtered to remove any impurities.
The resulting oil is a clear, light yellow liquid with a strong, sharp, and herbaceous aroma.

Synonyms
Oils,rosemary
Rosemaryabsolute
Rosemary oil 8000-25-7
Caswell no. 618e
Epa pesticide chemical code 597700
Fema no. 2991
Fema no. 2992
Garden rosemary oil
ROSIN
RUBBER LATEX, N° CAS : 9006-04-6, Nom INCI : RUBBER LATEX. Ses fonctions (INCI). Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles. Opacifiant : Réduit la transparence ou la translucidité des cosmétiques; Noms français : Caoutchouc; Caoutchouc naturel; Caoutchouc solide. Noms anglais : Natural rubber; Natural rubber latex, as inhalable allergenic proteins; Rubber, natural Le caoutchouc naturel solide et le latex de caoutchouc naturel sont des matériaux différents qui se distinguent à la fois par leurs propriétés, leur composition, leur procédé de production et leurs utilisations respectives, bien qu'ils proviennent tous deux du latex brut extrait principalement de l'heavea brasiliensis. Consultez aussi le produit : Latex de caoutchouc naturel (protéines). Utilisation et sources d'émission : Caoutchouc; RUBBER SOLUTION
RUBBER GRADE STEARIC ACID
Rubber Grade Stearic Acid is derived from renewable vegetable oils.
Rubber Grade Stearic Acid is used as raw material in making fatty acid amide, plasticizers and metallic soaps.
Rubber Grade Stearic Acid is a mixture of fatty acids composed primarily of octadecanoic (stearic), and hexadecanoic (palmitic 50%) acids to a controlled titer (molecular composition) and acid value (presence of unsaturation).

CAS: 67701-03-5
MF: C34H68O4
MW: 540.90132
EINECS: 266-928-5

Synonyms
C16-18-Alkylcarboxylicacid;STEARIC ACID - PALMITIC ACID;STEARIC PALMITIC ACID;STEARIC PALMITIC ACID MIXTURE;PALMITIC STEARIC ACID MIXTURE;PALMITIC ACID - STEARIC ACID;Stearic acid 50, Ph Eur;STEARIC-PALMITIC ACID POWDER TECHNICAL

Rubber Grade Stearic Acid is a light-colored, waxy solid with a characteristic fatty odor.
Rubber Grade Stearic Acid is available in flake form.
The flake form is primarily tallow-based.
Rubber Grade Stearic Acid has FDA status under 177.2600 regulations.
Rubber Grade Stearic Acid is derived from tallow feedstock.
Rubber Grade Stearic Acid is a renewable fatty acid that is extremely versatile and therefore used in the manufacturing process of many products.
Rubber Grade Stearic Acid is recommended as a mold release agent, activator, internal lubricant, accelerator, and surface lubricant in rubber processing.

Rubber Grade Stearic Acid is a premium product recognized for its high-quality and versatility in various industries.
Made in accordance with Ph Eur standards, Rubber Grade Stearic Acid comes with the CAS number 67701-03-5, ensuring its credibility and established reputation in the industry.
Rubber Grade Stearic Acid, also known as Acidum stearicum 50, comprises a balanced mixture of stearic acid and palmitic acid.
This exact composition elevates the product performance and widens its application scope.

TYPICAL PROPERTIES:
Titer, °C : 52min
Iodine Value: 10, max
Acid Number (mg KOH/g): 193 – 214
Saponification Number (mg KOH/g): 195 – 214
Color, Gardner: 4
Specific Gravity: 0.85
Melting Point, °C: 70

TYPICAL COMPOSITION:
Palmitic Acid: 50%
Stearic Acid: 35%
Oleic Acid: 9%
Miscellaneous Saturated Acids: 7%

Uses
Rubber Grade Stearic Acid is used as a dispersing agent and accelerator activator in rubber compounds.
Rubber Grade Stearic Acid aids dispersion of pigments and fillers and improves processing since it acts as a stock lubricant and can facilitate mold flow, improve extrusions and aid release.

Rubber Grade Stearic Acid boasts a vast range of applications across different industries:
Pharmaceuticals: Utilized as a lubricant, emulsifier, and hydrophobic agent.
Cosmetics: Acts as an emulsifier, thickening agent, and stabilizer.
Food: Used in food manufacturers for producing fatty acid salts, flavorings, and emulsifiers.
Textiles: Enhances weaving and reduces static in textile manufacturing processes.
Rubber: Augments processing and vulcanization of rubber products.
Polymer: Functions as a lubricant and dispersing agent.
Candle Making: Assists in solidifying and texture formation of candles.

Consumer Uses
Rubber Grade Stearic Acid is used in the following products: adhesives and sealants, washing & cleaning products, coating products, air care products, polishes and waxes, cosmetics and personal care products, biocides (e.g. disinfectants, pest control products), perfumes and fragrances, finger paints and inks and toners.
Other release to the environment of Rubber Grade Stearic Acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
RUBBER LATEX ( Caoutchouc)
sodium saccharinate; Sodium saccharine; Saccharin sodium; 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, sodium salt, dihydrate; EC / List no.: 612-173-5; CAS no.: 6155-57-3; Saccharin Sodium Salt 1,1-Dioxide-1,2-benzisothiazol-3(2H)-one Sodium Salt 1,1-Dioxyde de -1,2-benzothiazol-3-olate et de sodium [French] [ACD/IUPAC Name] 1,1-Dioxyde de 3-oxo-3H-1,2-benzothiazol-2-ide et de sodium [French] [ACD/IUPAC Name] 1,2-Benzisothiazol-3(2H)-one 1,1-dioxide sodium salt 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, sodium salt (1:1) [ACD/Index Name] 1,2-benzisothiazol-3-ol, 1,1-dioxide, sodium salt (1:1) [ACD/Index Name] 128-44-9 [RN] 204-886-1 [EINECS] 82385-42-0 [RN] I4807BK602 Natrium-1,2-benzothiazol-3-olat-1,1-dioxid [German] [ACD/IUPAC Name] Natrium-3-oxo-3H-1,2-benzothiazol-2-id-1,1-dioxid [German] [ACD/IUPAC Name] o-Benzoylsulfimide Sodium Salt Saccharin sodium Sodium 3-oxo-3H-1,2-benzothiazol-2-ide 1,1-dioxide [ACD/IUPAC Name] Sodium o-Sulfobenzimide Sucaryl Sucredulcor 1,1-Dioxide-1,2-benzisothiazol-3(2H)-one, sodium salt 1,2-BENZISOTHIAZOL-3(2H)-ONE, 1,1-DIOXIDE, SODIUM SALT 1,2-benzisothiazolin-3-one, 1,1-dioxide, sodium salt 16766-82-8 [RN] 1792234-08-2 [RN] Artificial sweetening substanz gendorf 450 Benzoic acid sulfimide, sodium Cristallose crystal lose crystallose dagutan EINECS 204-886-1 gendorf 450 Kristallose madhurin MFCD00013092 [MDL number] MFCD00040618 [MDL number] MFCD00149605 MFCD09287141 o-Benzoic Sulfimide Sodium Salt o-Sulfonbenzoic acid imide sodium salt Saccharin sodium hydrate Saccharin, sodium SACCHARIN, SODIUM SALT Saccharine sodium salt Saccharine soluble Saccharinnatrium Saccharoidum natricum Saxin Sodium [ACD/Index Name] [ACD/IUPAC Name] [Wiki] sodium 1,1,3-trioxo-2,3-dihydro-1λ6,2-benzothiazol-2-ide sodium 1,1-diketo-1,2-benzothiazol-2-id-3-one sodium 1,1-diketo-1,2-benzothiazol-3-olate sodium 1,1-dioxo-1,2-benzothiazol-2-id-3-one sodium 1,1-dioxo-1,2-benzothiazol-3-olate Sodium 1,2 benzisothiazolin-3-one 1,1-dioxide Sodium 1,2 benzisothiazolin-3-one-1,1-dioxide Sodium 1,2-benzisothiazol-3(2H)-one, 1,1-dioxide Sodium 1,2-benzisothiazolin-3-one 1,1-dioxide sodium 1,2-benzothiazol-3-one-2-ide-1,1-dioxide Sodium 2-benzosulphimide sodium 3-oxo-3H-1,2-benzisothiazol-2-ide 1,1-dioxide Sodium 3-oxo-3H-benzo[d]isothiazol-2-ide 1,1-dioxide Sodium benzosulphimide sodium o-benzosulfimide Sodium o-benzosulphimide sodium saccharide Sodium Saccharin Sodium saccharin, anhydrous sodium saccharinate Sodium saccharine Sodium3-oxo-3H-benzo[d]isothiazol-2-ide1,1-dioxide SOLUBLE SACCHARIN ST5405379 succaril Sucra Sucromat Sulphobenzoic imide, sodium salt Sweeta Sykose T5655012 Willosetten
Rubus fruticosus
fruitapone blackberry (Symrise); blackberry extract natural; european blackberry fruit extract; fruitapone blackberry GT (Symrise); european blackberry powder; dewberry fruit extract; extract of the fruit of the blackberry, rubus fruticosus l., rosaceae; rubus bergii fruit extract; rubus myrianthus fruit extract CAS NO:84787-69-9
Rubus idaeus
rubus idaeus bud extract; extract of the buds of rubus idaeus, rosaceae; red raspberry fruit extract CAS NO:84929-76-0
Rubus Ursinus Fruit Extract
rubus idaeus/ursinus fruit extract; extract of the fruit of the hybrid of rubus idaeus and rubus ursinus; rubus idaeus bud extract; extract of the buds of rubus idaeus, rosaceae; red raspberry fruit extract CAS NO:84929-76-0
RUCO 1016
RUCO 1016


CHEMICAL COMPOSITION: FLUOCARBON RESIN DISSOLVED IN SOLVENT


Ruco 1016 is C6-fluorocarbon with best performance
Ruco 1016 is solvent-based FC hydrophobing agent for oil, soil and water repellent finishes for all fiber types and leather.
Ruco 1016 is no curing at higher temperatures required.
Ruco 1016 contains flammable solvents.


Ruco 1016 is solvent-based fluorocarbon concentrates for effective C6-based water, oil and soil repellency.
With rapidly drying solvents, the application of solvent-based fluorocarbon concentrates has the general advantage that the water, oil and soil repellents orientate faster on substrates and, thus, their effects may develop more rapidly.


Ruco 1016 is dilutable with most hydrocarbons.
Ruco 1016 is C6 fluorocarbon polymer, dissolved in solvent
Ruco 1016 is free of perfluorooctanoic acid (PFOA*), perfluorooctane sulfonic acid (PFOS*)
Ruco 1016 is ecologically optimized agent for the water, oil and soil-repellent finishing of all fiber types



USES and APPLICATIONS of RUCO 1016:
Ruco 1016 is used Textile, Textile Finishing Assistants, and Other finishing auxiliaries
Field of application of Ruco 1016: Spray-on, and aerosol applications
Ruco 1016 is suitable for the aerosol spray can applications.
Ruco 1016 is diluted with a solvent and applied from suitable equipment.
The solvent selected influences the solubility as well as the water and oil-repellent properties of Ruco 1016.
Preferred solvents are isopropyl and butyl acetate, petroleum distillate 100° - 140 °C as well as acetate/isopropanol blends.



MODE OF APPLICATION OF RUCO 1016:
*2% Ruco 1016
*68% (n-heptane/iso-propanol 60/40)
*30% propellant: propane/butane



PROPERTIES OF RUCO 1016:
• C6-fl uorocarbon polymers based on acrylate
• Miscible with various organic solvents
• No temperature treatment necessary
• Suitable for all fi bre types
• No spots, even on dark textiles or leather
• Confers resistance to aqueous and oily soilings
• Dilutable with most hydrocarbons
• Contains flammable solvents
• No temperature treatment necessary



PHYSICAL and CHEMICAL PROPERTIES of RUCO 1016:
Appearance: yellowish, clear to slightly turbid, liquid
Solvent contained: isopropyl acetate
Miscibility: in most hydrocarbons
Flash point [°C]: 3
Boiling point [°C]: 90
Specific gravity at 20° C
[g/cm3]: ca. 1.0
Chemical Basis: C6 fluorocarbon polymers, PFOA and PFOS-free
Ionic Character: Non-ionic
Form: Liquid
Clear to slightly turbid, colorless to slightly yellow liquid
Specific gravity at 20 °C ca. 1.0 g/cmі
Not miscible with water



RUCO 1026
RUCO 1026


CHEMICAL BASIS: C6 fluorocarbon polymers, PFOA and PFOS-free


Ruco 1026 is solvent-based C6-FC hydrophobing agent for oil, soil and water repellent finishes for all fibre types and leather
Ruco 1026 is no curing at higher temperatures required.
Ruco 1026 is suitable for aerosol spray can applications.
Ruco 1026 contains flammable solvents.


Ruco 1026 is dilutable with isopropanol, esters as well as most hydrocarbons.
Ruco 1026 is solvent-based fluorocarbon concentrates for effective C6-based water, oil and soil repellency.
With rapidly drying solvents, the application of solvent-based fluorocarbon concentrates has the general advantage that the water, oil and soil repellents orientate faster on substrates and, thus, their effects may develop more rapidly.
This is highly advantageous for formulations used at ambient temperature.



USES and APPLICATIONS of RUCO 1026:
Ruco 1026 is used Textile, Textile Finishing Assistants, and Other finishing auxiliaries
Field of application of Ruco 1026: Spray-on, and aerosol applications



MODE OF APPLICATION OF RUCO 1026:
*2% RUCO 1026
*68% isopropanol
*30% propellant: propane/butane



PROPERTIES OF RUCO 1026:
• C6-fl uorocarbon polymers based on acrylate
• Miscible with various organic solvents
• No temperature treatment necessary
• Suitable for all fi bre types
• No spots, even on dark textiles or leather



PHYSICAL and CHEMICAL PROPERTIES of RUCO 1026:
Appearance: colourless, clear to slightly turbid, liquid
Solvent contained: isopropanol/ isopropyl acetate
Miscibility: in polar organic solvents and in most hydrocarbons
Flash point [°C]: 2
Boiling point [°C]: 80
Specific gravity at 20° C [g/cm3]: ca. 0.93
Ionic Character: Non-ionic
Form: Liquid
RUTİN
Quercetin-3-rutinoside hydrate, Vitamin P hydrate cas no:207671-50-9
RYTHMODAN
Rythmodan is an organoammonium phosphate.
Rythmodan belongs to a group of medicines called anti-arrhythmic agents used to treat irregular heartbeats.
Rythmodan is available in both oral and intravenous forms and has a low degree of toxicity.

CAS Number: 3737-09-5
Formula: C21H29N3O
Molar mass: 339.483 g·mol−1

Rythmodan is an antiarrhythmic chemical used in the treatment of ventricular tachycardia.
Rythmodan is a sodium channel blocker and is classified as a Class 1a anti-arrhythmic agent.

Rythmodan has a negative inotropic effect on the ventricular myocardium and significantly reduces contractility.
Rythmodan also has an anticholinergic effect on the heart, which is responsible for many negative side effects.
Rythmodan is available in both oral and intravenous forms and has a low degree of toxicity.

Rythmodan is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, for intermediate use only.
Rythmodan is used at industrial sites and in manufacturing.

Rythmodan is an organoammonium phosphate.

Rythmodan is a class Ia antiarrhythmic agent with cardiac depressant properties.
Rythmodan exerts Rythmodan actions by blocking both sodium and potassium channels in cardiac membrane during phase 0 of the action potential.

This slows the impulse conduction through the AV node and prolongs the duration of the action potential of normal cardiac cells in atrial and ventricular tissues.
Rythmodan prolongs the QT interval and causes a widening of the QRS complex.

Rythmodan also possesses some anticholinergic and local anaesthetic properties.
Rythmodan is used in the treatment of supraventricular tachycardia.

A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine.
Rythmodan also possesses some anticholinergic and local anesthetic properties.

Rythmodan belongs to a group of medicines called anti-arrhythmic agents used to treat irregular heartbeats.
An irregular heartbeat is a condition in which your heart beats irregularly, too fast, or too slow.
Rythmodan helps slow the heart rate and prevent arrhythmias (abnormal heart rhythms).

Rythmodan sulphate contains Rythmodan, ie anti-arrhythmic agents.
Rythmodan helps bring irregular heartbeats to a normal rhythm by blocking certain electrical signals in the heart.
Irregular heartbeat treatment reduces the risk of blood clots, heart attack or stroke.

Rythmodan should be taken as prescribed by the doctor.
Your doctor may monitor EKGs and blood pressure during treatment to monitor your dose.

Some people may experience common side effects such as blurred or double vision, stomach pain, little or no urination, and low blood sugar.
Most of these side effects of Rythmodan do not require medical attention and will gradually improve over time.
However, if the side effects persist, please consult your doctor.

Please tell your doctor if you are known to be allergic to Rythmodan or any other medicines.
Rythmodan is not recommended for use in children.
Pregnant or breastfeeding women are advised to consult a doctor before taking Rythmodan.

Before taking Rythmodan, tell your doctor if you have kidney or liver disease, enlarged prostate, glaucoma (increased eye pressure) or low potassium levels in the blood (hypokalaemia).
Do not take Rythmodan if you are already taking other medicines to regulate your heartbeat.

Do not drive or operate machinery as Rythmodan may cause blurred vision, dizziness and low blood pressure.
Use Rythmodan with caution if you are elderly (over 65 years of age), have a low body weight, or have kidney or liver problems.

Rythmodan is used to treat certain irregular heartbeats).
Rythmodan is in a class of medications called antiarrhythmic drugs.
Rythmodan works by making your heart more resistant to abnormal activity.

Continuing Education Activity:
Rythmodan is a chemical used to treat heart rhythm abnormalities that can be life-threatening, such as ventricular tachycardia/fibrillation, or associated with increased morbidity and mortality, such as atrial fibrillation and hypertrophic cardiomyopathy.
This activity reviews several important aspects of this chemical, including indications, mechanism of action, applications, side effects, contraindications, monitoring, and toxicity.
This important knowledge of this chemical can improve interprofessional healthcare team outcomes.

Objectives:
Describe the mechanism of action of Rythmodan.
Describe possible side effects of Rythmodan.

Explains the importance of monitoring when using Rythmodan as an antiarrhythmic chemical.
Outline professional team strategies for improving care coordination and communication when using Rythmodan to maximize the benefits of this chemical and minimize Rythmodan side effects.

Indications:
In 1962, new antiarrhythmic drugs were needed apart from quinidine and procainamide, which were the main antiarrhythmic agents available at the time.
Rythmodan is the selected agent among more than 500 compounds synthesized for the research program of new antiarrhythmic agents.
The chemical structures of Rythmodan are similar to the synthetic muscarinic antagonist lacquer, which explains Rythmodan anticholinergic property.

Although Rythmodan is rarely used for heart rhythm abnormalities due to the availability of newer drugs that provide better efficacy and favorable side-effect profiles, Rythmodan is still the drug of choice for vagal-mediated atrial fibrillation such as sleep-induced or atrial fibrillation in athlete groups.
The effectiveness of Rythmodan in these conditions is due to Rythmodan anticholinergic activity, which abolishes the parasympathetic tone.

Rythmodan is also a third-line antiarrhythmic agent for a patient with coronary artery disease.
Also, a patient with left ventricular hypertrophy has impaired depolarization, which can induce torsade de pointes.

Therefore, antiarrhythmics that prolong the QT interval are avoided, but if sotalol or amiodarone is unsuccessful or unsuitable, Rythmodan may be an alternative.
In a patient with atrial fibrillation and hypertrophic obstructive cardiomyopathy (HOCM), Rythmodan is the agent of choice, other than amiodarone, as Rythmodan may decrease the left ventricular outflow tract (LVOT) gradient (off-label use).

Data from a multicenter study of the safety and efficacy of Rythmodan in obstructive cardiomyopathy showed that Rythmodan significantly reduced the SVOT gradient from 75+/- 33 to 40+/-32 mmHg in 78 patients (66% of study subjects) (P<0.0001). has shown. ) and raises the New York Heart Association functional class (NYHA FC) from 23+/-07 to 17+/-06 (P<0.0001).
When Rythmodan is used in combination with a non-dihydropyridine calcium channel blocker or beta blocker, they can effectively prevent recurrence of AF in HCOM patients.

Patients with ventricular premature beat (VPB) or premature ventricular complexes (PVC) may have a high symptom burden.
Rythmodan can be used in patients without structural heart disease, although Rythmodan efficacy is less than ablation.
In addition, based on a randomized, double-blind, placebo-controlled one-year follow-up study, Rythmodan (n=44) was effective in maintaining sinus rhythm after electro cardioversion for atrial fibrillation compared to placebo (n=46) and was significantly different (%) at one-month follow-up. 70 vs 39%) and continues after twelve months (54% vs 30%).

Uses of Rythmodan:
Rythmodan is used to treat certain types of serious (possibly fatal) irregular heartbeat (such as sustained ventricular tachycardia).
Rythmodan is used to restore normal heart rhythm and maintain a regular, steady heartbeat.

Rythmodan is known as an anti-arrhythmic drug.
Rythmodan works by blocking certain electrical signals in the heart that can cause an irregular heartbeat.
Treating an irregular heartbeat can decrease the risk for blood clots, and this effect can reduce your risk of heart attack or stroke.

Usage of Rythmodan:
Rythmodan comes as a capsule and an extended-release (long-acting) capsule to take by mouth.
Rythmodan capsules may be taken every 6 or 8 hours.

The extended-release capsule is usually taken every 12 hours.
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.

Take Rythmodan exactly as directed.
Do not take more or less of Rythmodan or take it more often than prescribed by your doctor.

Swallow the extended-release capsules; do not open, crush, or chew them.

Rythmodan helps control your condition but will not cure it.
Continue to take Rythmodan even if you feel well.
Do not stop taking Rythmodan without talking to your doctor.

Mechanism of action of Rythmodan:
Rythmodan's Class 1a activity is similar to that of quinidine in that Rythmodan targets sodium channels to inhibit conduction.
Rythmodan depresses the increase in sodium permeability of the cardiac myocyte during Phase 0 of the cardiac action potential, in turn decreasing the inward sodium current.

This results in an increased threshold for excitation and a decreased upstroke velocity.
Rythmodan prolongs the PR interval by lengthening both the QRS and P wave duration.

This effect is particularly well suited in the treatment of ventricular tachycardia as Rythmodan slows the action potential propagation through the atria to the ventricles.
Rythmodan does not act as a blocking agent for beta or alpha adrenergic receptors, but does have a significant negative inotropic effect on the ventricular myocardium.
As a result, the use of Rythmodan may reduce contractile force up to 42% at low doses and up to 100% in higher doses compared to quinidine.

Levites proposed a possible secondary mode of action for Rythmodan, against reentrant arrhythmias after an ischemic insult.
Rythmodan decreases the inhomogeneity between infarcted and normal myocardium refractory periods; in addition to lengthening the refractory period.

This decreases the chance of re-entry depolarization, because signals are more likely to encounter tissue in a refractory state which cannot be excited.
This provides a possible treatment for atrial and ventricular fibrillation, as Rythmodan restores pacemaker control of the tissue to the SA and AV nodes.

Pharmacology and Biochemistry of Rythmodan:

MeSH Pharmacological Classification:

Anti-Arrhythmia Agents:
Agents used for the treatment or prevention of cardiac arrhythmias.
They may affect the polarization-repolarization phase of the action potential, Rythmodan excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers.
Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.

Obstructive hypertrophic cardiomyopathy:
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease, occurring in 1:500 individuals in the general population.
Rythmodan is estimated that there are 600,000 individuals in the United States with hypertrophic cardiomyopathy.

The most common variant of HCM presents with left ventricular (LV) intracavitary obstruction due to systolic anterior motion of the mitral valve, and mitral-septal contact, diagnosed readily with echocardiography.
Pharmacologic treatment with negative inotropic drugs is first-line therapy.

Beta-blockers are used first, and while they improve symptoms of shortness of breath, chest pain and exercise intolerance, they do not reduce resting LV intraventricular pressure gradients and often are inadequate to control symptoms.
Many investigators and clinicians believe that Rythmodan controlled release is the most potent agent available for reducing resting pressure gradients and improving symptoms.

Rythmodan has been actively used for more than 30 years.
Rythmodan administration for obstructive HCM has a IB recommendation in the 2020 American Heart Association/American College of Cardiology Foundation guidelines for treatment of obstructive HCM.
A IB treatment recommendation indicates that a treatment is recommended, and may be useful, and beneficial.

Negative inotropes improve LV obstruction by decreasing LV ejection acceleration and hydrodynamic forces on the mitral valve.
Rythmodan's particular efficacy is due to Rythmodan potent negative inotropic effects; in head-to-head comparison, Rythmodan is more effective for gradient reduction than either beta-blocker or verapamil.

Rythmodan is most often administered with beta-blockade.
When used in patients resistant to beta-blockade, Rythmodan is effective in 60% of cases, reducing symptoms and gradient to the extent that invasive procedures such as surgical septal myectomy are not required.

Rythmodan, despite Rythmodan efficacy, has one main side effect that has limited Rythmodan use in the US, though Rythmodan has seen wider application in Canada, UK and Japan.
Vagal blockade predictably causes dry mouth, and in men with prostatism, may cause urinary retention.
Teichman et al. showed that pyridostigmine used in combination with Rythmodan substantially alleviates vagolytic side effects without compromising antiarrhythmic efficacy.

This combination has also been shown to be effective and safe in obstructive HCM in a large cohort of patients.
Some clinicians prescribe pyridostigmine sustained release (marketed in the US as Mestinon Timespan) to every patient begun on Rythmodan.
This combination increases acceptance of higher Rythmodan dosing, important since there is a dose-response correlation in obstructive HCM, higher doses yielding lower gradients.

Another concern about Rythmodan has been the hypothetical potential for inducing sudden death from Rythmodan type 1 anti-arrhythmic effects.
However, a multicenter registry and two recent cohort registries have largely reduced this concern, by showing sudden death rates lower than that observed from the disease itself.

These concerns about the drug must be viewed from the clinical perspective that Rythmodan is generally the last agent that is tried for patients before they are referred for invasive septal reduction with surgical septal myectomy (an open-heart operation) or alcohol septal ablation (a controlled heart attack).
Both of these invasive procedures have risk of morbidity and mortality.

For selected patients, a trial of oral Rythmodan is a reasonable approach before proceeding to invasive septal reduction.
Patients who respond to Rythmodan are continued on the drug.

Those who continue to have disabling symptoms or who experience side effects are promptly referred for septal reduction.
Using such a stepped strategy, investigators have reported that survival does not differ from that observed in the age-matched normal United States population.

Extracardiac effects:
Atropine like effects (anticholinergic)
Dry mouth
Constipation
Urinary retention – Rythmodan should not be given to patients with symptomatic prostatism.
Blurred vision
Glaucoma
Rash
Agranulocytosis

Additionally, Rythmodan may enhance the hypoglycaemic effect of gliclazide, insulin, and metformin.

Metabolism of Rythmodan:
Rythmodan can cause hypoglycemia, perhaps due to increased secretion of insulin, and can also potentiate the effects of conventional hypoglycemic drugs.
This effect may be due to Rythmodan chief metabolite mono-N dealkylRythmodan, since many of the reported cases of hypoglycemia have been in patients with renal impairment, in which the metabolite accumulates.

In six subjects who were being considered for treatment with Rythmodan, serum glucose concentrations were measured at 13, 15, 17, and 19 hours after supper, with no further food, with and without the added administration of two modified-released tablets of Rythmodan 150 mg with supper and 12 hours later.
Rythmodan significantly reduced the serum glucose concentration at all measurement times by an average of 0.54 mmol/l.
The fall in serum glucose concentration was not related to the serum concentration of Rythmodan or the serum creatinine concentration; Rythmodan was greater in older patients and in underweight patients.

Hypoglycemia has also been reported in a 70-year-old woman with type 2 diabetes mellitus taking Rythmodan.

Clinical data of Rythmodan:
Trade names: Norpace
AHFS/Drugs.com: Monograph
MedlinePlus: a682408
Pregnancy category: AU: B2
Routes ofadministration: Oral, intravenous
ATC code: C01BA03 (WHO)

Legal status:
UK: POM (Prescription only)
US: ℞-only

Pharmacokinetic data of Rythmodan:
Bioavailability: High
Protein binding: 50% to 65% (concentration-dependent)
Metabolism: Hepatic (CYP3A4-mediated)
Elimination half-life: 6.7 hours (range 4 to 10 hours)
Excretion: Renal (80%)

Identifiers of Rythmodan:
IUPAC name: (RS)-4-(Diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide
CAS Number: 3737-09-5
PubChem CID: 3114
IUPHAR/BPS: 7167
DrugBank: DB00280
ChemSpider: 3002
UNII: GFO928U8MQ
KEGG: D00303
ChEBI: CHEBI:4657
ChEMBL: ChEMBL517
CompTox Dashboard (EPA): DTXSID1045536
ECHA InfoCard: 100.021.010

Properties of Rythmodan:
Formula: C21H29N3O
Molar mass: 339.483 g·mol−1
Melting point: 94.5 to 95 °C (202.1 to 203.0 °F)
SMILES: O=C(N)C(c1ncccc1)(c2ccccc2)CCN(C(C)C)C(C)C
InChI: InChI=1S/C21H29N3O/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25)
Key:UVTNFZQICZKOEM-UHFFFAOYSA-N

Molecular Weight: 437.5 g/mol
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 7
Rotatable Bond Count: 8
Exact Mass: 437.20795813 g/mol
Monoisotopic Mass: 437.20795813 g/mol
Topological Polar Surface Area: 137Ų
Heavy Atom Count: 30
Complexity: 459
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

Names of Rythmodan:

Regulatory process names:

Disopyramide

IUPAC names:
4-(diisopropylamino)-2-phenyl-2-pyridin-2-ylbutanamide
4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide
Disopyramide

Other identifiers:
3737-09-5

Synonyms of Rythmodan:
Disopyramide PHOSPHATE
22059-60-5
Norpace
Disopyramide PHOSPHATE SALT
Rythmodan
Norpace Cr
SC 7031 phosphate
Dirythmin sa
Diso-duriles
DisopyramidePhosphate
EINECS 244-756-1
SC 7031 (phosphate)
NSC-756744
SC-13957
SC-7031 PHOSPHATE
CHEBI:4658
N6BOM1935W
22059-60-5 (phosphate)
SC 13957
Norpace (TN)
2-(1-(Ammoniocarbonyl)-3-(diisopropylammonio)-1-phenylpropyl)pyridinium phosphate
Disopyramid phosphate
4-(diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide phosphate
4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide;phosphoric acid
alpha-(2-Diisopropylaminoethyl)-alpha-phenyl-2-pyridineacetamide phosphate
(+-)-alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide phosphate (1:1)
2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, phosphate
2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, phosphate (1:1)
2-Pyridineacetamide, alpha-(2-(diisopropylamino)ethyl)-alpha-phenyl-, phosphate
alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide phosphate (1:1)
2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-, (+-)-, phosphate (1:1)
SR-01000003039
Disopyramide (phosphate)
UNII-N6BOM1935W
SCHEMBL41810
MLS000028431
SPECTRUM1500261
C21H29N3O.H3O4P
CHEMBL1201020
HMS501I11
DTXSID30944685
Disopyramide phosphate (JAN/USP)
HMS1920I14
HMS2094K15
HMS2234B16
HMS3259J21
HMS3261C04
HMS3369L05
HMS3652M20
HMS3885J07
Pharmakon1600-01500261
Disopyramide PHOSPHATE [MI]
XAA05960
Disopyramide PHOSPHATE [JAN]
Tox21_500411
CCG-40209
Disopyramide PHOSPHATE [USAN]
HY-12533A
NSC756744
Disopyramide PHOSPHATE [VANDF]
AKOS040744844
Disopyramide PHOSPHATE [MART.]
Disopyramide PHOSPHATE [USP-RS]
Disopyramide PHOSPHATE [WHO-DD]
LP00411
NC00683
NSC 756744
Disopyramide phosphate [USAN:BAN:JAN]
NCGC00093836-01
NCGC00093836-02
NCGC00093836-03
NCGC00093836-04
NCGC00261096-01
SMR000058438
Disopyramide PHOSPHATE [ORANGE BOOK]
LS-130131
Disopyramide PHOSPHATE [EP MONOGRAPH]
Disopyramide phosphate [USAN:USP:BAN:JAN]
EU-0100411
FT-0630479
S4143
SW196836-3
SW196836-4
Disopyramide PHOSPHATE [USP MONOGRAPH]
C07740
D 6035
D00637
SR-01000003039-2
SR-01000003039-6
Q27106430
4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide
(R)-4-(diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide phosphate
4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide,phosphoric acid
4-DIISOPROPYLAMINO-2-PHENYL-2-(2-PYRIDYL)BUTYRAMIDE PHOSPHATE
Disopyramide phosphate, European Pharmacopoeia (EP) Reference Standard
Disopyramide phosphate, United States Pharmacopeia (USP) Reference Standard
(+/-)-.ALPHA.-(2-(DIISOPROPYLAMINO)ETHYL)-.ALPHA.-PHENYL-2-PYRIDINEACETAMIDE PHOSPHATE (1:1)
2-PYRIDINEACETAMIDE, .ALPHA.-(2-(BIS(1-METHYLETHYL)AMINO)ETHYL)-.ALPHA.-PHENYL-, (+/-)-, PHOSPHATE (1:1)
223-110-2 [EINECS]
2-pyridineacetamide, a-[2-[bis(1-methylethyl)amino]ethyl]-a-phenyl-
2-Pyridineacetamide, α-(2-(bis(1-methylethyl)amino)ethyl)-α-phenyl-
2-Pyridineacetamide, α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl- [ACD/Index Name]
3737-09-5 [RN]
4-(Diisopropylamino)-2-phenyl-2-(2-pyridinyl)butanamid [German] [ACD/IUPAC Name]
4-(Diisopropylamino)-2-phenyl-2-(2-pyridinyl)butanamide [ACD/IUPAC Name]
4-(Diisopropylamino)-2-phényl-2-(2-pyridinyl)butanamide [French] [ACD/IUPAC Name]
4-(Diisopropylamino)-2-phenyl-2-(2-pyridyl)butyramide
4-(Diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide
4-(dipropan-2-ylamino)-2-phenyl-2-(pyridin-2-yl)butanamide
a-[2-(Diisopropylamino)ethyl]-a-phenyl-2-pyridineacetamide
a-[2-[Bis(1-methylethyl)amino]ethyl]a-phenyl-2-pyridineacetamide
disopiramida [Spanish] [INN]
Disopyramide [French] [INN]
Disopyramide [BAN] [INN] [JAN] [JP15] [USAN] [Wiki]
Disopyramide, (R)-
Disopyramide, (S)-
disopyramidum [Latin] [INN]
Isorythm
Lispine
MFCD00057366 [MDL number]
Norpace [Trade name]
Rythmodan [Trade name]
α-[2-(DIISOPROPYLAMINO)ETHYL]-α-PHENYL-2-PYRIDINEACETAMIDE
α-Diisopropylaminoethyl-α-phenylpyridine-2-acetamide
дизопирамид [Russian] [INN]
ديسوبيراميد [Arabic] [INN]
丙吡胺 [Chinese] [INN]
Disopyramide free base
NORPACE CR
Rythmodan-La
ξ-Disopyramide
[3737-09-5] [RN]
1309283-08-6 [RN]
2-Pyridineacetamide, α-(2-(diisopropylamino)ethyl)-α-phenyl-
2-Pyridineacetamide, α-[2-(diisopropylamino)ethyl]-α-phenyl-
2-Pyridineacetamide, α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl-
3737-09-5 (free base)
38236-46-3 [RN]
4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide
4-(diisopropylamino)-2-phenyl-2-pyridin-2-ylbutanamide
4-[bis(methylethyl)amino]-2-phenyl-2-(2-pyridyl)butanamide
4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide
4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanimidic acid
4-[di(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide
4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide
492056 [Beilstein]
4-Diisopropylamino-2-phenyl-2-(2-pyridyl)-butyramide
54687-36-4 [RN]
74464-83-8 [RN]
74464-84-9 [RN]
BS-17145
DB00280
Dicorantil
Disopiramida
Disopiramida [INN-Spanish]
Disopyramide-d5
Disopyramidum
Disopyramidum [INN-Latin]
MFCD00069254 [MDL number]
n-desalkyl Disopyramide
Norpace®
Ritmodan
Rythmodan P [Trade name]
Rythmodan®
Searle 703
α-(2-(Diisopropylamino)ethyl)-α-phenyl-2-pyridineacetamide
α-(2-(Diisopropylamino)ethyl)-α-phenyl-2-pyridineacetamide
α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl-2-pyridineacetamide
γ-Diisopropylamino-α-phenyl-α-(2-pyridyl)butyramide
γ-Diisopropylamino-α-phenyl-α-(2-pyridyl)butyramide
дизопирамид
ديسوبيراميد
丙吡胺
S-(+) mandelic acid
2-phenylglycolic acid; a-Hydroxy-benzeneacetic acid; alpha-Hydroxy-benzeneacetic acid; amygdalic acid; d-2-hydroxy-2-phenylacetic acid; Hydroxy(phenyl)acetic acid; L-2-HYDROXY-PHENYLACETIC ACID; L-A-HYDROXYPHENYLACETIC ACID; L-ALPHA-HYDROXYPHENYLACETIC ACID; L-AMYGDALIC ACID; (+)-L-MANDELIC ACID; L-(+)-MANDELIC ACID; L-MANDELIC ACID; L-PHENYLGLYCOLIC ACID; (+)-MANDELIC ACID; MANDELIC ACID, L-(+)-; (S)-2-HYDROXY-2-PHENYLACETIC ACID; (S)-ALPHA-HYDROPHENYLACETIC ACID; (S)-(+)-ALPHA-HYDROXYPHENYLACETIC ACID; (S)-ALPHA-HYDROXYPHENYLACETIC ACID CAS NO:17199-29-0
SABOSTAB UV 65

Sabostab UV 65 is a hindered amine light stabilizer (HALS) commonly used in various industries, including plastics, coatings, and adhesives.
Sabostab UV 65 acts as a stabilizer against the effects of ultraviolet (UV) radiation, which can cause degradation and discoloration of materials over time.

CAS Number: 129757-67-1
EC Number: 406-750-9

Synonyms: Hindered amine light stabilizer 65, HALS 65, UV stabilizer 65, UV absorber 65, Hindered amine 65, Sabostab 65, Light stabilizer 65, Sabo UV 65, HALS UV 65, Hindered amine stabilizer 65, UV blocker 65, UV protector 65, Photostabilizer 65, UV absorber HALS 65, HALS light stabilizer 65, HALS UV absorber 65, Hindered amine light absorber 65, UV light stabilizer 65, Hindered amine stabilizer UV 65, UV light absorber 65, Hindered amine UV stabilizer 65, HALS UV blocker 65



APPLICATIONS


Sabostab UV 65 is commonly used in the automotive industry for exterior trim components.
Sabostab UV 65 is applied in the manufacturing of bumpers, mirror housings, and door handles to enhance durability and color retention.
Sabostab UV 65 is utilized in the production of outdoor furniture to protect against UV-induced degradation.

Sabostab UV 65 helps to maintain the appearance and integrity of plastic chairs, tables, and benches exposed to sunlight.
Sabostab UV 65 is incorporated into building materials such as vinyl siding, window profiles, and roofing materials to prolong their lifespan.
Sabostab UV 65 is added to PVC pipes and fittings used in outdoor plumbing applications to prevent degradation.

Sabostab UV 65 is used in agricultural films and greenhouse coverings to protect crops from UV radiation.
Sabostab UV 65 helps to extend the service life of agricultural films, reducing the need for frequent replacement.

Sabostab UV 65 is employed in the production of sports equipment such as playground structures and athletic field markers.
Sabostab UV 65 helps to prevent fading and degradation of plastic surfaces exposed to sunlight in outdoor recreational areas.

Sabostab UV 65 is applied in the manufacturing of outdoor signage, traffic barriers, and safety equipment to maintain visibility and durability.
Sabostab UV 65 is used in the production of marine equipment such as boat hulls, decks, and accessories.
Sabostab UV 65 helps to protect marine plastics from the damaging effects of UV radiation and saltwater exposure.
Sabostab UV 65 is employed in the packaging industry for UV-stable containers, bottles, and films used in outdoor applications.

Sabostab UV 65 ensures that packaged goods remain protected and visually appealing during storage and transportation.
Sabostab UV 65 is added to electrical enclosures, lighting fixtures, and other outdoor electrical components to enhance weather resistance.
Sabostab UV 65 helps to prevent yellowing and brittleness of plastic housings and enclosures exposed to sunlight.

Sabostab UV 65 is utilized in the production of garden tools, hoses, and irrigation systems for outdoor use.
Sabostab UV 65 ensures that garden equipment remains durable and functional despite prolonged exposure to sunlight.

Sabostab UV 65 is applied in the manufacturing of outdoor pet products such as kennels, toys, and feeding bowls.
Sabostab UV 65 helps to maintain the color and integrity of plastic pet accessories exposed to outdoor conditions.

Sabostab UV 65 is used in the production of outdoor recreational equipment such as camping gear and backpacks.
Sabostab UV 65 ensures that outdoor gear remains resilient and visually appealing even after prolonged use in sunlight.

Sabostab UV 65 is incorporated into outdoor lighting fixtures, solar panels, and landscaping features to maintain their appearance and functionality.
Sabostab UV 65 is an essential component in a wide range of outdoor applications where UV protection is required to ensure long-lasting performance and aesthetics.

Sabostab UV 65 is utilized in the production of outdoor recreational vehicles such as ATVs, jet skis, and snowmobiles.
Sabostab UV 65 helps to protect the plastic components of recreational vehicles from fading, cracking, and deterioration caused by UV exposure.

Sabostab UV 65 is added to outdoor signage and billboards to maintain color vibrancy and legibility over time.
Sabostab UV 65 ensures that outdoor advertisements remain visually appealing and effective in all weather conditions.

Sabostab UV 65 is applied in the manufacturing of playground equipment, park benches, and picnic tables for outdoor use.
Sabostab UV 65 helps to preserve the structural integrity and appearance of plastic play structures and outdoor furniture.

Sabostab UV 65 is incorporated into swimming pool accessories such as pool floats, loungers, and toys.
Sabostab UV 65 protects poolside plastics from discoloration and degradation caused by prolonged exposure to sunlight and chlorine.

Sabostab UV 65 is used in the production of outdoor storage containers, bins, and sheds.
Sabostab UV 65 ensures that outdoor storage solutions remain durable and weather-resistant over time.

Sabostab UV 65 is applied in the manufacturing of agricultural equipment such as irrigation systems, seed trays, and greenhouse components.
Sabostab UV 65 helps to protect agricultural plastics from UV damage and extend their lifespan in outdoor environments.

Sabostab UV 65 is utilized in the production of outdoor pet habitats such as kennels, hutches, and aviaries.
Sabostab UV 65 ensures that pet enclosures remain sturdy and visually appealing despite exposure to sunlight and weathering.

Sabostab UV 65 is added to outdoor lighting fixtures such as garden lights, pathway markers, and solar lamps.
Sabostab UV 65 helps to maintain the clarity and functionality of outdoor lighting solutions over time.

Sabostab UV 65 is incorporated into outdoor seating solutions such as stadium seats, bleachers, and concert chairs.
Sabostab UV 65 ensures that outdoor seating remains comfortable and aesthetically pleasing despite exposure to the elements.

Sabostab UV 65 is applied in the manufacturing of agricultural nets, shade sails, and crop covers.
Sabostab UV 65 protects agricultural textiles from UV degradation and extends their lifespan in outdoor farming applications.
Sabostab UV 65 is utilized in the production of outdoor recreation gear such as tents, sleeping bags, and backpacks.

Sabostab UV 65 ensures that outdoor gear remains durable and weather-resistant during outdoor adventures.
Sabostab UV 65 is added to outdoor vehicle accessories such as bike racks, roof racks, and cargo carriers.

Sabostab UV 65 helps to protect vehicle accessories from UV damage and maintain their appearance over time.
Sabostab UV 65 is an essential component in a wide range of outdoor applications where UV protection is critical to ensuring longevity and performance.



DESCRIPTION


Sabostab UV 65 is a hindered amine light stabilizer (HALS) commonly used in various industries, including plastics, coatings, and adhesives.
Sabostab UV 65 acts as a stabilizer against the effects of ultraviolet (UV) radiation, which can cause degradation and discoloration of materials over time.
Sabostab UV 65 helps to prevent photochemical degradation by absorbing and dissipating UV light energy, thus protecting the integrity and appearance of the material.

Sabostab UV 65 is often incorporated into formulations of polymers, such as polyethylene, polypropylene, polyvinyl chloride (PVC), and others, to extend their service life and maintain their mechanical properties when exposed to outdoor conditions.
Additionally, Sabostab UV 65 may provide thermal stability and improve the weatherability of materials, making it a valuable additive in products that are subjected to harsh environmental conditions.


Sabostab UV 65 is a highly effective hindered amine light stabilizer (HALS).
Sabostab UV 65 is designed to protect materials from the degrading effects of ultraviolet (UV) radiation.

Sabostab UV 65 is specifically formulated to extend the service life of polymers exposed to outdoor conditions.
Sabostab UV 65 helps to prevent photochemical degradation, which can lead to discoloration, embrittlement, and loss of mechanical properties.
Sabostab UV 65 acts by absorbing UV light energy and dissipating it harmlessly as heat.
Sabostab UV 65 is suitable for use in a wide range of polymers, including polyethylene, polypropylene, and PVC.

Sabostab UV 65 provides excellent protection against both UV-A and UV-B radiation.
Sabostab UV 65 is characterized by its high efficiency and long-lasting performance.

Sabostab UV 65 is compatible with other additives commonly used in polymer formulations.
Sabostab UV 65 is available in various physical forms, including powders, granules, and liquids, to suit different processing requirements.
Sabostab UV 65 is easy to incorporate into polymer matrices during compounding or processing.
Sabostab UV 65 helps to maintain the appearance and integrity of plastic products exposed to outdoor weathering.

Sabostab UV 65 is particularly useful in applications such as automotive parts, building materials, and outdoor furniture.
Sabostab UV 65 can also improve the thermal stability of polymers, reducing the risk of thermal degradation.

Sabostab UV 65 is highly recommended for products that require long-term outdoor exposure.
Sabostab UV 65 undergoes rigorous testing to ensure compliance with regulatory standards and industry specifications.

Sabostab UV 65 is known for its low volatility and minimal impact on polymer processing conditions.
Sabostab UV 65 is an essential component of formulations aimed at achieving durable and weather-resistant materials.
Sabostab UV 65 contributes to the overall performance and durability of plastic products in challenging environmental conditions.

Sabostab UV 65 is often chosen for its proven track record of reliability and effectiveness.
Sabostab UV 65 enhances the appearance of finished products by preserving their color and gloss.

Sabostab UV 65 provides peace of mind to manufacturers and end-users by ensuring long-lasting protection against UV degradation.
Sabostab UV 65 is trusted by industries worldwide for its consistent quality and performance.

Sabostab UV 65 offers cost-effective solutions for extending the lifespan of outdoor plastic products.
Sabostab UV 65 plays a crucial role in maintaining the quality and value of plastic materials in a variety of applications.



PROPERTIES


Appearance: Typically a white to light yellow solid or liquid, depending on the formulation.
Odor: Odorless or may have a slight characteristic odor.
Melting Point: Varies depending on the specific formulation and purity, typically between 50°C to 150°C.
Boiling Point: Decomposes before reaching a specific boiling point.
Density: Variable depending on the physical form and concentration, typically between 0.9 to 1.2 g/cm^3.
Solubility: Insoluble in water; soluble in organic solvents such as alcohols, ketones, and aromatic hydrocarbons.
Vapor Pressure: Low vapor pressure at normal temperatures.
pH: Not applicable for non-aqueous substances.
Specific Gravity: Typically around 1.0 to 1.5 g/cm^3, depending on the formulation and concentration.
Viscosity: Varies depending on the physical form and concentration, typically between 50 to 5000 cP.
Molecular Weight: Varies depending on the specific chemical composition, typically ranges from 500 to 2000 g/mol.



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air immediately.
Allow the person to rest in a well-ventilated area and monitor their breathing.
If breathing difficulties persist or worsen, seek medical attention immediately.
Provide artificial respiration if the person is not breathing, and seek medical help promptly.


Skin Contact:

Remove contaminated clothing and shoes immediately.
Wash the affected skin thoroughly with soap and water for at least 15 minutes.
If irritation or redness develops, seek medical attention.
Wash contaminated clothing before reuse.
If skin irritation persists or worsens, seek medical advice from a healthcare professional.


Eye Contact:

Flush the eyes with lukewarm water or saline solution immediately, holding the eyelids open.
Continue flushing the eyes for at least 15 minutes, ensuring that the entire eye surface is rinsed.
Remove contact lenses if present and easy to do so after flushing the eyes.
Seek immediate medical attention from an eye care professional.
Do not rub the eyes, as this may exacerbate irritation or injury.


Ingestion:

Do not induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth thoroughly with water and spit out the rinse water.
Do not give anything by mouth to an unconscious person.
Seek immediate medical attention or contact a poison control center.
Provide medical personnel with information about the ingested substance and its container if available.


General First Aid:

In all cases, provide supportive care as necessary based on the individual's symptoms and condition.
Keep the affected person warm and comfortable.
Monitor vital signs such as pulse, breathing, and blood pressure.
Do not administer any medications unless instructed to do so by medical personnel.
If medical attention is required, provide transportation to the nearest medical facility.
Follow any additional instructions provided by medical professionals or poison control authorities.



HANDLING AND STORAGE


Handling:

Use appropriate personal protective equipment (PPE), including safety glasses, gloves, and protective clothing, when handling Sabostab UV 65.
Avoid inhalation of dust, vapors, or aerosols. Use respiratory protection if ventilation is inadequate.
Avoid skin contact with the substance.

Wear impermeable gloves and protective clothing to prevent skin exposure.
Use in a well-ventilated area to minimize exposure to airborne particles. Install local exhaust ventilation if necessary.
Avoid generating dust or aerosols during handling. Use mechanical handling equipment or enclosed systems to minimize dust formation.

Do not eat, drink, or smoke while handling Sabostab UV 65. Wash hands thoroughly after handling.
Store Sabostab UV 65 away from incompatible materials, including strong acids, bases, oxidizing agents, and reducing agents.
Keep containers tightly closed when not in use to prevent contamination and moisture ingress.

Avoid contact with eyes and mucous membranes. In case of contact, rinse thoroughly with water and seek medical attention if irritation persists.
If Sabostab UV 65 comes into contact with clothing, remove contaminated clothing immediately and wash skin with soap and water.
Handle Sabostab UV 65 with care to prevent spills and leaks. Clean up spills promptly and dispose of waste material according to local regulations.
Do not allow Sabostab UV 65 to enter drains, sewers, or waterways. Contain spills with suitable absorbent materials and dispose of properly.


Storage:

Store Sabostab UV 65 in a cool, dry, well-ventilated area away from direct sunlight and sources of heat or ignition.
Keep containers tightly closed and upright to prevent leakage or spillage.
Store Sabostab UV 65 away from food, beverages, and animal feed to prevent contamination.

Do not store near heat sources or open flames.
Keep away from sparks, flames, and other sources of ignition.
Store Sabostab UV 65 separately from strong oxidizing agents and reducing agents to prevent chemical reactions.
Ensure storage area is equipped with appropriate fire detection and suppression equipment.

Check containers regularly for signs of damage or deterioration. Replace damaged containers immediately.
Follow all local regulations and guidelines for the storage of hazardous chemicals, including Sabostab UV 65.
Keep storage area clean, dry, and well-organized to minimize the risk of accidents and spills.
Keep Sabostab UV 65 out of reach of children, unauthorized personnel, and animals.

Store Sabostab UV 65 in its original packaging and label containers clearly with product name and hazard information.
Keep Safety Data Sheets (SDS) readily available for reference by personnel handling the substance.
Follow manufacturer recommendations and guidelines for the safe storage and handling of Sabostab UV 65.
SACCHARIN
Benzoic sulfimide; Sodium saccharin; Sodium saccharine; Saccharin; sodium cas no: 128-44-9
Saccharin Sodium ( sodium saccharide, sodium saccharinate, Sodium saccharine)
SACCHARIN, SACCHARIMIDE; Saccharine; N° CAS : 81-07-2; Saccharine,Saccharin; SACCHARIN ACID; SACCHARIN INSOLUBLE; SACCHARINOL; Nom INCI : SACCHARIN. Nom chimique : 1,2-Benzisothiazol-3(2H)-one 1,1-dioxide; N° EINECS/ELINCS : 201-321-0; Additif alimentaire : E954 Ses fonctions (INCI).Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit; Agent d'hygiène buccale : Fournit des effets cosmétiques à la cavité buccale (nettoyage, désodorisation et protection). Saccharin; Noms français : 1,2-BENZISOTHIAZOL-3(2H)-ONE, 1,1-DIOXIDE; 1,2-BENZISOTHIAZOLIN-3-ONE, 1,1-DIOXIDE; 1,2-DIHYDRO-2-KETOBENZISOSULFONAZOLE; 1,2-DIHYDRO-2-KETOBENZISOSULPHONAZOLE; 2,3-DIHYDRO-3-OXOBENZISOSULFONAZOLE; 2,3-DIHYDRO-3-OXOBENZISOSULPHONAZOLE ; 2-SULPHOBENZOIC IMIDE; 3-BENZISOTHIAZOLINONE 1,1-DIOXIDE; 3-HYDROXYBENZISOTHIAZOLE-S,S-DIOXYDE; ANHYDRO-O-SULFAMINEBENZOIC ACID; ANHYDRO-ORTHO-SULPHAMINEBENZOIC ACID; BENZO-2-SULPHIMIDE; BENZO-SULPHINIDE; BENZOIC SULFIMIDE; BENZOIC SULPHIMIDE; BENZOSULFINIDE; BENZOSULPHIMIDE; BENZOSULPHIMIDE-2 ;O-BENZOIC SULFIMIDE; O-BENZOIC SULPHIMIDE; O-BENZOSULFIMIDE; O-BENZOSULPHIMIDE; O-BENZOYL SULFIMIDE; O-BENZOYL SULPHIMIDE; O-SULFOBENZIMIDE; O-SULFOBENZOIC ACID IMIDE; ORTHO-BENZOIC SULPHIMIDE; ORTHO-BENZOSULPHIMIDE; ORTHO-BENZOYL SULPHIMIDE; ORTHO-SULPHOBENZIMIDE; ORTHO-SULPHOBENZOIC ACID IMIDE; SACCHARIMIDE; Saccharine; SULFIMIDE D'ORTHO-BENZOYLE Noms anglais : Saccharin; SACCHARIN ACID; SACCHARIN INSOLUBLE; SACCHARINOL Utilisation et sources d'émission: Produit alimentaire 1,1-Dioxyde de -1,2-benzothiazol-3(2H)-one [French] [ACD/IUPAC Name] 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide [ACD/Index Name] 1,2-Benzothiazol-3(2H)-on-1,1-dioxid [German] [ACD/IUPAC Name] 1,2-Benzothiazol-3(2H)-one 1,1-dioxide [ACD/IUPAC Name] 2,3-Dihydroxy-1,2-benzisothiazol-3-one-1,1-dioxide 228-971-8 [EINECS] 2-Sulfobenzoic acid imide 81-07-2 [RN] DE4200000 FST467XS7D Garantose Glucid Gluside MFCD00005866 [MDL number] o-Benzoic acid sulfimide o-benzoic sulfimide Sacarina [Portuguese] Sacarina [Spanish] Saccarina [Italian] Saccharin [German] Saccharine [French] SACCHARINOL Saccharinose Saccharol Sakarin [Turkish] Saxin T56 BSWMVJ [WLN] UNII-FST467XS7D サッカリン [Japanese] 糖精 [Chinese] 1,​2-​benzisothiazol-​3(2h)​-​one, 1,​1-​dioxide 1,1-diketo-1,2-benzothiazol-3-one 1,1-DIOX-1,2-BENZISOTHIAZOL-3-ONE 1,1-Dioxide-1,2-benzisothiazol-3(2H)-one 1,1-Dioxide-1,2-benzisothiazolin-3-one 1,1-Dioxido-3-oxo-2,3-dihydrobenzo[d]isothiazole 1,1-dioxo-1,2-benzothiazol-3-one 1,1-Dioxo-1,2-dihydro-1λ*6*-benzo[d]isothiazol-3-one 1,1-Dioxo-1,2-dihydro-1λ*6*-benzo[d]-isothiazol-3-one 1,1-Dioxo-1,2-dihydro-benzo[d]isothiazol-3-one 1,2-benzisothiazol-3(2h)-one 1,1-dioxide 1,2-Benzisothiazol-3(2H)-one -1,1-dioxide 1,2-Benzisothiazolin-3-one 1,1-dioxide 1,2-Benzisothiazolin-3-one, 1,1-dioxide 1,2-Benzisothiazoline-3-one 1,1-dioxide 1,2-benzothiazol-3(2H)-one-1,1-dioxyde 1,2-Dihydro-2-ketobenzisosulfonazole 1,2-Dihydro-2-ketobenzisosulphonazole 2,3-Dihydro-1,2-benzisothiazol-3-one-1,1-dioxide 2,3-Dihydro-1,2-benzoisothiazol-3-one-1,1-dioxide 2,3-dihydro-1λ6,2-benzothiazole-1,1,3-trione 2,3-dihydro-1λ6,2-benzothiazole-1,1,3-trione 2,3-Dihydro-3-oxobenzisosulfonazole 2,3-Dihydro-3-oxo-Benzisosulfonazole 2,3-Dihydro-3-oxobenzisosulphonazole 2H-1λ6,2-benzothiazole-1,1,3-trione 2-hydrobenzo[d]isothiazole-1,1,3-trione 2-Sulfobenzoic imide 2-Sulfobenzoicimide 2-Sulphobenzoic imide 3-Benzisothiazolinone 1,1-dioxide 3-Hydroxybenzisothiazole S,S-dioxide 3-Hydroxybenzisothiazole-S,S-dioxide 4-allylpyrocatechol formaldehyde acetal 5-19-01-00553 [Beilstein] 5-bromobenzo[d]isothiazol-3(2H)-one 1,1-dioxide Anhydro-o-sulfaminebenzoic acid BENZENE,1-ALLYL,3,4-METHYLENEDIOXY SAFROLE Benzisosulfonazole, 2,3-dihydro-3-oxo- benzo[d]isothiazol-3(2H)-one 1,1-dioxide Benzo-2-sulfiide Benzo-2-sulphimide Benzoic acid sulfimide Benzoic sulfimide Benzoic sulphimide Benzosulfimide Benzosulfimide, O- Benzosulfinide Benzosulphimide Benzo-sulphinide Benzoylsulfonic Imide D012439 E954 Glycophenol Hermesetas http://www.hmdb.ca/metabolites/HMDB0029723 IN-00581 (Saccharin) Kandiset LSA Natreen NCGC00094918-01 NCGC00094918-02 NCGC00094918-03 Neosaccharin o-benzoic sulfimide, 98+% o-Benzoic sulphimide o-Benzosulfimide o-Benzosulphimide o-Benzoyl sulfimide o-Benzoyl sulphimide O-Benzoylsulfimide o-Sulfobenzimide o-sulfobenzimide 98% o-Sulfobenzoic acid imide O-Sulfobenzoic imide Pharmakon1600-01501171 Sacarina Saccharimide saccharin, 98+% Saccharin|1,2-Benzisothiazol-3(2H)-one Saccharina saccharine [Wiki] Sacharin [Czech] SPECTRUM1501171 ST073992 Stilalgin Sucre edulcor Sucrette Sulfobenzimide, O- Sweeta Sykose syncal UNII:FST467XS7D Zaharina
Saccharine ( SACCHARIN)
CALCIUM SACCHARIN, N° CAS : 6485-34-3 - Saccharine de calcium, Nom INCI : CALCIUM SACCHARIN, Nom chimique : 1,2-Benzisothiazol-3(2H)-one 1,1-dioxide, calcium salt N° EINECS/ELINCS : 229-349-9, Additif alimentaire : E954, Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit, Agent d'hygiène buccale : Fournit des effets cosmétiques à la cavité buccale (nettoyage, désodorisation et protection)
Saccharine de calcium
SUCROSE, N° CAS : 57-50-1 - Saccharose, Origine(s) : Végétale, Synthétique. Autres langues : Sacarosa, Saccarosio. Nom INCI : SUCROSE. Nom chimique : Sucrose. N° EINECS/ELINCS : 200-334-9. Le saccharose que l'on appelle aussi le sucre de table, est un disaccharide que l'on trouve couramment dans les aliments. Il est obtenu par cristallisation du jus de canne à sucre ou de betterave à sucre extrait par pressage ou diffusion, puis clarifié et évaporé. Dans les cosmétiques, on le retrouve un peu partout, il est utilisé en tant qu'aromatisant, humectant (retient l'humidité dans les produits).Ses fonctions (INCI) Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau Agent d'entretien de la peau : Maintient la peau en bon état Agent apaisant : Aide à alléger l'inconfort de la peau ou du cuir chevelu; Noms français : ALPHA-D-GLUCOPYRANOSYL-BETA-D-FRUCTOFURANOSIDE BETA-D-FRUCTOFURANOSYL-ALPHA-D-GLUCOPYRANOSIDE Saccharose SUCRE SUCRE BLANC RAFFINE SUCRE DE TABLE Sucrose Noms anglais : BEETSUGAR CANE SUGAR Saccharose Sucrose SUCROSE (CANE SUGAR) SUGAR TABLE SUGAR WHITE SUGAR Utilisation et sources d'émission: Fabrication de produits alimentaires et de produits pharmaceutiques; Sucrose [Wiki] (+)-Sucrose (2R,3R,4S,5S,6R)-2-{[(2S,3S,4S,5R)-3,4-Dihydroxy-2,5-bis(hydroxymethyl)tetrahydro-2-furanyl]oxy}-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (2R,3R,4S,5S,6R)-2-{[(2S,3S,4S,5R)-3,4-Dihydroxy-2,5-bis(hydroxyméthyl)tétrahydro-2-furanyl]oxy}-6-(hydroxyméthyl)tétrahydro-2H-pyran-3,4,5-triol 200-334-9 [EINECS] 57-50-1 [RN] 90825 [Beilstein] D-Sucrose MFCD00006626 [MDL number] Sucrose, Low Endotoxin sugar [Wiki] α-D-Glucopyranoside de β-D-fructofuranosyle [French] α-D-Glucopyranoside, β-D-fructofuranosyl α-D-Glucopyranoside, β-D-fructofuranosyl [ACD/Index Name] α-D-Glucopyranosyl β-D-fructofuranoside β-D-Fructofuranoside, α-D-glucopyranosyl β-D-Fructofuranosyl α-D-glucopyranoside β-D-Fructofuranosyl α-D-glucopyranoside [ACD/IUPAC Name] β-D-Fructofuranosyl-α-D-glucopyranosid [German] β-D-Fructofuranosyl-α-D-glucopyranoside &α;-D-glucopyranosyl &β;-D-fructofuranoside &β;-D-fructofuranosyl-(2↔1)-&α;-D-glucopyranoside (α-D-Glucosido)-β-D-fructofuranoside 112642-98-5 [RN] 1-O-Benzoyl-β-D-fructofuranosyl α-D-glucopyranoside [ACD/IUPAC Name] 1-α-D-Glucopyranosyl-2-β-D-fructofuranoside 2-[(2S,3S,4S,5R)-2,5-bis(hydroxymethyl)-3,4-dihydroxyoxolan-2-yloxy](4S,5S,2R,3R,6R)-6-(hydroxymethyl)-2H-3,4,5,6-tetrahydropyran-3,4,5-triol ACS Amerfand Amerfond Beet sugar Cane sugar Confectioner's sugar D-(+)-Saccharose D-(+)-Sucrose D(+)-Sucrose (USP-NF, BP, Ph. Eur., JP) D-Saccharose Fru(β2-1α)Glc Fructofuranoside, α-D-glucopyranosyl, β-D GLC-(1-2)FRU Glucopyranoside, β-D-fructofuranosyl, α-D Granulated sugar http://www.hmdb.ca/metabolites/HMDB0000258 MFCD00047542 [MDL number] Microse Rock candy Rohrzucker sacarosa Saccharose [Wiki] Sacharose suc Sucralox Sucrose Biochemical grade SUCROSE-(FRUCTOSE-1-3H(N)) Sucrose, BP, EP, USP grade α-D-Glucopyranoside, β-D-fructofuranosyl- α-D-Glucopyranosylbeta-D-fructofuranoside β-d-fructofuranoside
SACCHAROMİCİES SEREVİCİA
saccharomyces cerevisiae; Autolyzed yeast extract (Saccharomyces cerevisiae); Baker's yeast; Baker's yeast (Saccharomyces Cerevisiae) cas no:68876-77-7
Saccharose ( SUCROSE)
SAFFLOWER OIL; SAFFLOWER OIL, HIGH OLEIC; SAFFLOWER SEED OIL; carthamustinctoriusoil; fatsandglyceridicoils,safflower; Hi-oleicsaffloweroil; thistleoil; Safflower seed oil from Carthamus tinctorius seed CAS NO:8001-23-8
S-ADENOSYL METHYONİNE
S-Adenosyl methionine; (S)-2-amino-4-((SS)-(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonio)butanoate; S-Adenosyl-L-methionine; SAM-e; SAMe, AdoMet, ademethionine cas no: 29908-03-0
SAFFLOWER OIL FATTY ACID
2-Hydroxybenzoic acid;o-Hydroxybenzoic acid; Phenol-2-carboxylic acid; Salonil; 2-Hydroxybenzoic acid; 2-Hydroxybenzenecarboxylic acid; 2-Carboxyphenol; o-Carboxyphenol; Acido O-idrossibenzoico (Italian); Acido Salicilico (Italian); 2-hydroxy-Benzoic Acid; o-Hydroxybenzoic Acid; Kyselina 2-hydroxybenzoova (Czech); Kyselina Salicylova (Czech); Orthohydroxybenzoic Acid CAS NO:69-72-7
Safflower Oil High Oleic
SYNONYMS SAFFLOWER OIL;SAFFLOWER OIL, HIGH OLEIC;SAFFLOWER SEED OIL;carthamustinctoriusoil;fatsandglyceridicoils,safflower;Hi-oleicsaffloweroil;thistleoil;Safflower seed oil from Carthamus tinctorius seed CAS NO:8001-23-8
Safflower Oil Regular
SYNONYMS SAFFLOWER OIL;SAFFLOWER OIL, HIGH OLEIC;SAFFLOWER SEED OIL;carthamustinctoriusoil;fatsandglyceridicoils,safflower;Hi-oleicsaffloweroil;thistleoil;Safflower seed oil from Carthamus tinctorius seed CAS NO:8001-23-8
Safran Ekstraktı
Crocus Sativus Flower Extract; extract of the flowers of the saffron crocus, crocus sativus l., iridaceae; extrapone saffron ; saffron extract cas no:84604-17-1
SAHLEP AROMASI
sahlep flavor
Salatalık Ekstraktı
Cucumis Sativus Extract; cucumber extract; extract obtained from the whole plant of the cucumber, cucumis sativus l., cucurbitaceae cas no:89998-01-6
Salcylic acid
2-Hydroxybenzoic acid;o-Hydroxybenzoic acid; Phenol-2-carboxylic acid; Salonil; 2-Hydroxybenzoic acid; 2-Hydroxybenzenecarboxylic acid; 2-Carboxyphenol; o-Carboxyphenol; Acido O-idrossibenzoico (Italian); Acido Salicilico (Italian); 2-hydroxy-Benzoic Acid; o-Hydroxybenzoic Acid; Kyselina 2-hydroxybenzoova (Czech); Kyselina Salicylova (Czech); Orthohydroxybenzoic Acid CAS NO:69-72-7
SALICYLIC ACID (2-HYDROXYBENZOIC ACID)
Salicylic Acid (2-hydroxybenzoic acid) is an organic compound with the formula HOC6H4COOH.
Salicylic Acid (2-hydroxybenzoic acid) is an odorless white to light tan solid.


CAS-Number: 69-72-7
EC Number: 200-712-3
MDL number: MFCD00002439
Chemical Name: 2 – Hydroxybenzoic Acid
Linear Formula: 2-(HO)C6H4CO2H
Molecular Formula: C7H6O3



2-Hydroxybenzoic acid, 2-HYDROXYBENZOIC ACID, ACIDUM SALICYLICUM, ACETYLSALISYLIC ACID IMP C, ACETYLSALICYLIC ACID IMPURITY C, FEMA 3985, SALICYCLIC ACID, SALICYLIC ACID, RETARDER TSA, salicylic acid, 2-Hydroxybenzoic acid, 69-72-7, o-hydroxybenzoic acid, 2-Carboxyphenol, o-Carboxyphenol, Rutranex, Salonil, Retarder W, Duoplant, Keralyt, Psoriacid-S-stift, Freezone, Saligel, Ionil, Salicylic acid soap, Stri-Dex, Verrugon, Salicylic acid collodion,
Benzoic acid, 2-hydroxy-, 2-Hydroxybenzenecarboxylic acid, Phenol-2-carboxylic acid, Orthohydroxybenzoic acid, Acido salicilico, Kyselina salicylova, 2-hydroxy-benzoic acid, CCRIS 6714, HSDB 672, AI3-02407, CHEBI:16914, BRN 0774890, NSC-180, UNII-O414PZ4LPZ, EINECS 200-712-3, O414PZ4LPZ, MFCD00002439, DTXSID7026368, FEMA NO. 3985, CHEMBL424, MLS000069653, DTXCID206368, NSC180, K 537, EC 200-712-3, 29656-58-4, SMR000059163, Acid, Salicylic, ortho-Hydroxybenzoic Acid, o Hydroxybenzoic Acid, 2 Hydroxybenzoic Acid, Acid, o-Hydroxybenzoic, Acid, 2-Hydroxybenzoic, ortho Hydroxybenzoic Acid, Acid, ortho-Hydroxybenzoic, NSC629474, phenol derivative, 7, Salicylic acid (TN), SCHEMBL1967, SALICYLIC ACID [MI], Oprea1_040343, KBioSS_001428, BIDD:ER0602, NCGC00159447-01, NCGC00159447-02, NCGC00159447-04, NCGC00159447-06, NCGC00257065-01, NCGC00259022-01, FT-0645123, FT-0674502, FT-0674503, H0206, H1342, Salicylic Acid Technical Grade, Unichem Salac, 2-Hydroxybenzoic acid, 2-Carboxyphenol, Salicylic acid, 2-HYDROXYBENZOIC ACID,ACIDUM SALICYLICUM, ACETYLSALISYLIC ACID IMP C,ACETYLSALICYLIC ACID IMPURITY C,FEMA 3985,SALICYCLIC ACID,SALICYLIC ACID,RETARDER TSA, Salicylic, Acid,Salicylic, 2 Hydroxybenzoic Acid, Acido Salicilico, Sa - Salicylic Acid, O-Hydroxybenzoic Acid, O Hydroxybenzoic Acid, Salicylic Aci, Acid,2-Hydroxybenzoic, Acidum Salicylicum, O-Carboxyphenol, Salicylic Acid Preparation, Acid,O-Hydroxybenzoic, Kyselina Salicylova, Salicylic Preparation, Acid,Ortho-Hydroxybenzoic, Acido O-Idrossibenzoico, Kyselina 2-Hydroxybenzoova, Caswell No. 731, Benzoic Acid,2-Hydroxy- (10), 2-Carboxyphenol,2-Hydroxybenzenecarboxylate, 2-Hydroxybenzenecarboxylic acid, 2-Hydroxybenzoate, 2-Hydroxybenzoic acid, Benzoic acid, 2-hydroxy-, Benzoic acid, o-hydroxy-, o-Carboxyphenol, o-Hydroxybenzoate, o-Hydroxybenzoic acid, Orthohydroxybenzoic acid, Phenol-2-carboxylate, Phenol-2-carboxylic acid, Psoriacid-S-Stift, Salicyclic acid, Salicylate, Salicylic acid, Saligel, Salonil, Trans-Ver-Sal, 2 Hydroxybenzoic acid Acid, 2-hydroxybenzoic, Acid, salicylic, Acid, O-hydroxybenzoic, Acid, ortho-hydroxybenzoic, O Hydroxybenzoic acid, Ortho hydroxybenzoic acid, Ortho-hydroxybenzoic acid, Advanced pain relief callus removers, Advanced pain relief corn removers, Clear away wart remover, Compound W, Duofil wart remover, Duoplant, Freezone, Ionil, Ionil plus, K 537, K 557, Retarder W, Rutranex, Salicylic acid collodion, Salicylic acid soap, Stri-dex, SA, Benzoic acid, 2-hydroxy-, o-Hydroxybenzoic acid, Phenol-2-carboxylic acid, Psoriacid-S-Stift, Retarder W, Rutranex, Salicylic acid collodion, Salonil, 2-Hydroxybenzoic acid, Acido salicilico, Keralyt, Kyselina 2-hydroxybenzoova, Kyselina salicylova, Orthohydroxybenzoic acid, Duoplant, Freezone, Ionil, Saligel, Compound W, 2-Hydroxybenzenecarboxylic acid, 2-Carboxyphenol, o-Carboxyphenol, Advanced pain relief callus removers, Advanced pain relief corn removers, Clear away wart remover, Dr. Scholl's Callus Removers, Duofil Wart Remover, Ionil plus, Salicylic acid soap, Stri-Dex, Benzoic acid, o-hydroxy-, NSC 180, Trans-Ver-Sal, Domerine, Duofilm, Fostex, Pernox, Salicylic acid & Sulfur Soap, Sebucare, Sebulex, component of Fostex medicated bar and cream, component of Keralyt, Retarder SAX, component of Solarcaine first aid spray, component of Tinver, 7681-06-3, 8052-31-1, Salicyclic acid, Domerine (Salt/Mix), Duofilm (Salt/Mix), Fostex (Salt/Mix), Pernox (Salt/Mix), Salicylic acid & Sulfur Soap (Salt/Mix), Sebucare (Salt/Mix), Sebulex (Salt/Mix), component of Fostex medicated bar and cream (Salt/Mix), component of Keralyt (Salt/Mix), Retarder SAX (Salt/Mix), component of Solarcaine first aid spray (Salt/Mix), component of Tinver (Salt/Mix)



A colorless, bitter-tasting solid, Salicylic Acid (2-hydroxybenzoic acid) is a precursor to and a metabolite of aspirin (acetylsalicylic acid).
Salicylic Acid (2-hydroxybenzoic acid) is a plant hormone, and has been listed by the EPA Toxic Substances Control Act (TSCA) Chemical Substance Inventory as an experimental teratogen.


The name is from Latin salix for willow tree, from which Salicylic Acid (2-hydroxybenzoic acid) was initially identified and derived.
Salicylic Acid (2-hydroxybenzoic acid) is an ingredient in some anti-acne products.
Salts and esters of Salicylic Acid (2-hydroxybenzoic acid) are known as salicylates.


Salicylic Acid (2-hydroxybenzoic acid) is an odorless white to light tan solid.
Salicylic Acid (2-hydroxybenzoic acid) sinks and mixes slowly with water.
Salicylic Acid (2-hydroxybenzoic acid) is a useful phosphor in the vacuum ultraviolet spectral range, with nearly flat quantum efficiency for wavelengths between 10 and 100 nm.


Salicylic Acid (2-hydroxybenzoic acid) fluoresces in the blue at 420 nm.
Salicylic Acid (2-hydroxybenzoic acid) is easily prepared on a clean surface by spraying a saturated solution of the salt in methanol followed by evaporation.


Salicylic Acid (2-hydroxybenzoic acid) a monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position.
Salicylic Acid (2-hydroxybenzoic acid) is a compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically.
Salicylic Acid (2-hydroxybenzoic acid) has bacteriostatic, fungicidal, and keratolytic actions.


Salicylic Acid (2-hydroxybenzoic acid) is a metabolite found in or produced by Escherichia coli .
Salicylic Acid (2-hydroxybenzoic acid) is a beta hydroxy acid that occurs as a natural compound in plants.
Salicylic Acid (2-hydroxybenzoic acid) has direct activity as an anti-inflammatory agent and acts as a topical antibacterial agent due to its ability to promote exfoliation.


Salicylic Acid (2-hydroxybenzoic acid) is a compound obtained from the bark of the white willow and wintergreen leaves.
Salicylic Acid (2-hydroxybenzoic acid) has bacteriostatic, fungicidal, and keratolytic actions.
Salicylic Acid (2-hydroxybenzoic acid) is obtained from the bark of the white willow and wintergreen leaves.


Salicylic Acid (2-hydroxybenzoic acid) has a role as an antiinfective agent, an antifungal agent, a keratolytic drug, an EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor, a plant metabolite, an algal metabolite and a plant hormone.
Salicylic Acid (2-hydroxybenzoic acid) is a conjugate acid of a salicylate.


Salicylic Acid (2-hydroxybenzoic acid) is lipophilic monohydroxybenzoic acid.
Salicylic Acid (2-hydroxybenzoic acid) a type of phenolic acid and a beta-hydroxy acid (BHA).
Beta hydroxy acid is found as a natural compound in plants.


This colourless crystalline organic acid, Salicylic Acid (2-hydroxybenzoic acid), is broadly in use in organic synthesis.
Salicylic Acid (2-hydroxybenzoic acid) is derived from the metabolism of salicin.
Salicylic Acid (2-hydroxybenzoic acid) is a crystalline organic carboxylic acid and has keratolytic, bacteriostatic and fungicidal properties.


Salicylic Acid (2-hydroxybenzoic acid) can be in use as an antiseptic and as a food preservative when consumed in small quantities.
Salicylic Acid (2-hydroxybenzoic acid) has a carboxyl group attached to it i.e., COOH.
Salicylic Acid (2-hydroxybenzoic acid) is odourless and is colourless.


Salicylic Acid (2-hydroxybenzoic acid) is probably known for its use as an important ingredient in topical anti-acne products.
The salts and esters of Salicylic Acid (2-hydroxybenzoic acid) are salicylates.
Salicylic Acid (2-hydroxybenzoic acid) is on the World Health Organization’s List of Essential Medicines.


Salicylic Acid (2-hydroxybenzoic acid) is the safest and most effective medicines needed in a health system.
Salicylic Acid (2-hydroxybenzoic acid), also known as 2-Hydroxybenzoic Acid, 2-Carboxyphenol, and o-Hydroxybenzoic Acid has the chemical formula C7H6O3.
Salicylic Acid (2-hydroxybenzoic acid) has a role as antiinfective agent, antifungal agent, keratolytic drug, EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor, plant metabolite, algal metabolite and plant hormone.


Salicylic Acid (2-hydroxybenzoic acid) is the conjugate acid of a salicylate.
Salicylic Acid (2-hydroxybenzoic acid), also known as o-hydroxybenzoic acid, is a component with a structure similar to β-hydroxy acid, which can not only soften the stratum corneum, but also loosen the horn plugs to unclog pores, as well as certain antibacterial and anti-inflammatory effects.


Salicylic Acid (2-hydroxybenzoic acid) appears as an odorless, white-colored to light tan solid with an acrid taste.
Salicylic Acid (2-hydroxybenzoic acid) is slightly soluble in Water, therefore, when added to Water, it sinks and slowly mixes with it at ambient conditions.


Salicylic Acid (2-hydroxybenzoic acid) is in use in the treatment of wart infections.
The mechanism of Salicylic Acid (2-hydroxybenzoic acid) by which professionals treats warts infection is similar to its keratolytic action.
Firstly, Salicylic Acid (2-hydroxybenzoic acid) dehydrates the skin cells that are affected by warts and thereby it gradually leads to its shedding off from the body.


Salicylic Acid (2-hydroxybenzoic acid) also activates the immune reaction of the body towards the viral wart infection by initiating a mild inflammatory reaction.
Salicylic Acid (2-hydroxybenzoic acid) is one of the major components of anti-dandruff shampoos.


Salicylic Acid (2-hydroxybenzoic acid) also helps in clearing away the dead and flaky skin cells from your scalp.
Salicylic Acid (2-hydroxybenzoic acid) is a monohydroxybenzoic acid, benzoic acid with a hydroxy group in the ortho position.
Salicylic Acid (2-hydroxybenzoic acid) is obtained from the bark of white willow and wintergreen leaves.


This knowledge was repeatedly quoted by famous Greek and Roman physicians such as Galen.
Salicylic Acid (2-hydroxybenzoic acid), also known as 2-carboxyphenol or 2-hydroxybenzoate, belongs to the class of organic compounds known as salicylic acids.


These are ortho-hydroxylated benzoic acids.
Salicylic Acid (2-hydroxybenzoic acid) exists in all living species, ranging from bacteria to plants to humans.
Based on a literature review a significant number of articles have been published on Salicylic Acid (2-hydroxybenzoic acid).


In an early (1966) biosynthetic process, researchers at Kerr-McGee Oil Industries (now part of Andarko Petroleum) prepared Salicylic Acid (2-hydroxybenzoic acid) via the microbial degradation of naphthalene.
Salicylic Acid (2-hydroxybenzoic acid) is now commercially biosynthesized from phenylalanine.


Acetylsalicylic acid (aspirin), a prodrug to Salicylic Acid (2-hydroxybenzoic acid), is made by an entirely different process.
Curiously, Salicylic Acid (2-hydroxybenzoic acid) is also a metabolite of aspirin.
Salicylic Acid (2-hydroxybenzoic acid) and its esters are used as food preservatives, in skin-care products and other cosmetics, and in topical medicines.


In 2015, J. L. Dangl, S. L. Lebeis, and co-workers at the University of North Carolina, Chapel Hill, discovered that native Salicylic Acid (2-hydroxybenzoic acid) plays a role in determining which microbes are in the root microbiome of Arabidopsis thaliana, a weed that grows in Europe and Asia.
Salicylic Acid (2-hydroxybenzoic acid), also called 2-hydrobenzoic or phenolic acid, is a colorless substance in the form of crystals or powder.


Salicylic Acid (2-hydroxybenzoic acid) is one of the most commonly used types of hydroxybenzoic acid.
Phenolic acid is highly soluble in polar solvents of organic origin, such as diethyl ether or ethanol, but slightly soluble in water and carbon disulfide.
The density of Salicylic Acid (2-hydroxybenzoic acid) is 1.44 g/cm³, melting occurs at 159°C, and boils at 211°C.


The production of Salicylic Acid (2-hydroxybenzoic acid) is based on the Kolbe-Schmitt reaction: the carboxylation of sodium phenolate when exposed to carbon dioxide with the creation of the required pressure and temperature for 8-10 hours.
Two grades of the product are produced: A - for the preparation of medicines, B - for other areas of application.


The chemical formula of Salicylic Acid (2-hydroxybenzoic acid) is C7H6O3.
Salicylic Acid (2-hydroxybenzoic acid) is a natural product extract from Willow bark, well known as an antiinflammatory and antinociceptive agent and a close structural relative to acetylsalicylic acid (aspirin).


Salicylic Acid (2-hydroxybenzoic acid) is a ubiquitous plant hormone with many regulatory functions involved in local disease resistance mechanisms and systemic acquired resistance.
The antiinflammatory and antinociceptive effects produced by Salicylic Acid (2-hydroxybenzoic acid) and its derivatives in animals are due to inhibition of COX-1 and COX-2 (cyclooxygenase) enzyme activity and suppression of prostaglandin biosynthesis.


Salicylic Acid (2-hydroxybenzoic acid) is also of interest as a starting material for the organic synthesis of more elaborate COX suppressors and other chemical structures.
Salicylic Acid (2-hydroxybenzoic acid) (from Latin salix, willow tree) is a monohydroxybenzoic acid, a type of phenolic acid and a beta hydroxy acid.


Salicylic Acid (2-hydroxybenzoic acid) has the formula C7H6O3.Salicylic Acid (2-hydroxybenzoic acid) is not easily soluble in water, but is easily soluble in organic solvents such as ethanol, ether, propanol, and turpentine.
Salicylic Acid (2-hydroxybenzoic acid) exists in willow bark, white pearl leaves, and sweet birch in nature, and is the "anti-inflammatory drug" of plants.


Humans have long discovered the medicinal properties of willow plant extracts (natural Salicylic Acid (2-hydroxybenzoic acid)).
Ancient Sumerian clay tablets have records of using willow leaves to treat arthritis.


The oldest medical text in ancient Egypt, the Ebers Papyrus, records that the pain-relieving properties of dried willow leaves were known to the Egyptians at least more than 2,000 BC.
The ancient Greek physician Hippocrates documented the medicinal properties of willow bark in the 5th century BC.



USES and APPLICATIONS of SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
Cosmetic Uses of Salicylic Acid (2-hydroxybenzoic acid): antidandruff agents fragrance, hair conditioning, keratolytics, preservatives, skin conditioning.
Uses in manufacturing: Salicylic Acid (2-hydroxybenzoic acid) is used as a food preservative, a bactericide, and an antiseptic.


Salicylic Acid (2-hydroxybenzoic acid) is used in the production of other pharmaceuticals, including 4-aminosalicylic acid, sandulpiride, and landetimide (via salethamide).
Salicylic Acid (2-hydroxybenzoic acid) has long been a key starting material for making acetylsalicylic acid (aspirin).


Aspirin (acetylsalicylic acid or ASA) is prepared by the esterification of the phenolic hydroxyl group of Salicylic Acid (2-hydroxybenzoic acid) with the acetyl group from acetic anhydride or acetyl chloride.
ASA is the standard to which all the other non-steroidal anti-inflammatory drugs (NSAIDs) are compared.


In veterinary medicine, this group of drugs is mainly used for treatment of inflammatory musculoskeletal disorders.
Bismuth subsalicylate, a salt of bismuth and Salicylic Acid (2-hydroxybenzoic acid), "displays anti-inflammatory action (due to salicylic acid) and also acts as an antacid and mild antibiotic".


It is the active ingredient in stomach-relief aids such as Pepto-Bismol and some formulations of Kaopectate.
Other derivatives include methyl salicylate used as a liniment to soothe joint and muscle pain and choline salicylate used topically to relieve the pain of mouth ulcers.


Salicylic Acid (2-hydroxybenzoic acid) is used in agriculture, forestry and fisheries, health care and scientific research and development
Salicylic Acid (2-hydroxybenzoic acid) is used in machine wash fluids/detergents, automotive care products, paints, coatings or adhesives, fragrances, air fresheners, coolants in refrigerators and oil-based electric heaters.


Salicylic Acid (2-hydroxybenzoic acid) is particularly in use in the pharmaceutical industry.
The most common use of Salicylic Acid (2-hydroxybenzoic acid) is in the preparation of an analgesic, aspirin, which is an acetylated derivative of Salicylic Acid (2-hydroxybenzoic acid).


Another analgesic formed from it is methyl salicylate, an esterified product of Salicylic Acid (2-hydroxybenzoic acid).
Both of these analgesics are in use to treat headache and other body aches.
Aminosalicylic acid is used to induce remission in ulcerative colitis, and has been used as an antitubercular agent often administered in association with isoniazid.


Salicylic Acid (2-hydroxybenzoic acid)'s salts, the salicylates, are used as analgesics.
Salicylic Acid (2-hydroxybenzoic acid) is used in the following products: Fertilizers, cosmetics and personal care products, laboratory chemicals and medicines.


In medicine, preparations based on Salicylic Acid (2-hydroxybenzoic acid) are used as an antipyretic, antiseptic, antirheumatic and anti-tuberculosis agent, which has an analgesic and anti-inflammatory effect.
These are aspirin, salicylamide, para-aminosalicylic acid, Lassar paste, preparations for the treatment of corns, ointments, powders.


At food enterprises, Salicylic Acid (2-hydroxybenzoic acid) is used as an antiseptic in the manufacture of canned foods.
Salicylic Acid (2-hydroxybenzoic acid) is added as a component to cosmetics.
Its antibacterial and exfoliating properties make Salicylic Acid (2-hydroxybenzoic acid) possible to soften and remove the keratinized top layer of the skin.


Salicylic Acid (2-hydroxybenzoic acid) is used as a reagent and indicator in chemical reactions.Salicylic Acid (2-hydroxybenzoic acid), GR 99%+ Cas 69-72-7 - used as a reference standard in salicylate quantification by reverse-phase high-performance liquid chromatography (RP-HPLC).
Both oil of wintergreen (methyl 2-hydroxybenzoate) and Salicylic Acid (2-hydroxybenzoic acid) (2-hydroxybenzoic acid) are widely used as pharmaceuticals.


The manufacture of aspirin from Salicylic Acid (2-hydroxybenzoic acid) is of major importance.
Industrially, Salicylic Acid (2-hydroxybenzoic acid) is manufactured at high temperature and pressure from the phenol sodium salt and carbon dioxide, with an annual worldwide production of about 50,000 tonnes.


Salicylic Acid (2-hydroxybenzoic acid) is a white solid first isolated from the bark of willow trees (Salix spp.), from which it gets its name.
Salicylic Acid (2-hydroxybenzoic acid) also occurs as the free acid or its esters in many plant species.
Salicylic Acid (2-hydroxybenzoic acid) can be made from methyl 2-hydroxybenzoate which is obtained as oil of wintergreen by distillation from the leaves of Gaultheria procunbers.


Salicylic Acid (2-hydroxybenzoic acid) also in use as a mild antiseptic effect known as a bacteriostatic agent.
Salicylic Acid (2-hydroxybenzoic acid) does not kill the existing bacteria and hence not an antibacterial agent but prevent the growth of bacteria wherever applied.


Common Uses and Applications of Salicylic Acid (2-hydroxybenzoic acid): Treatment for various minor skin conditions, Food preservative, Analytic reagent, Industries,Food & Beverage, Pharmaceutical, and R&D/Laboratory.


Salicylic Acid (2-hydroxybenzoic acid) is used semiconductors, nanoparticles, photoresists, lubricating oils, UV absorbers, adhesive, leather, cleaner, hair dye, soaps, cosmetics, pain medication, analgesics, antibacterial agent, treatment of dandruff, hyperpigmented skin, tinea pedis, onychomycosis, osteoporosis, beriberi, fungicidal skin disease, autoimmune disease.


-Medicine uses of Salicylic Acid (2-hydroxybenzoic acid):
Salicylic Acid (2-hydroxybenzoic acid) as a medication is commonly used to remove the outer layer of the skin.
As such, Salicylic Acid (2-hydroxybenzoic acid) is used to treat warts, psoriasis, acne vulgaris, ringworm, dandruff, and ichthyosis.
Similar to other hydroxy acids, Salicylic Acid (2-hydroxybenzoic acid) is an ingredient in many skincare products for the treatment of seborrhoeic dermatitis, acne, psoriasis, calluses, corns, keratosis pilaris, acanthosis nigricans, ichthyosis, and warts.



FUNCTIONS OF SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
*Acne treatment, acne treatment - Salicylic Acid (2-hydroxybenzoic acid) is fat-soluble, can penetrate deep into pores to dissolve oil and unclog sebaceous glands; its acidity can dissolve hardened oil and keratin, so that the keratin plugs in the hair follicles can be loosened, and it also has mild anti-inflammatory properties. inflammatory and antibacterial effects.


*Conditioning keratin and improving skin photoaging - Salicylic Acid (2-hydroxybenzoic acid) has a two-way keratin regulating effect and can remove old keratin, so some patients will experience slight scaling, but this is a manifestation of keratin renewal, and it is not suitable for immature keratinization.

On the contrary, the stratum corneum cells have the effect of promoting keratinization and maturation.
Long-term sunlight exposure can cause skin keratin thickening, skin hypertrophy, skin furrows deepen, skin ridges bulge, forming thick and deep wrinkles, so Salicylic Acid (2-hydroxybenzoic acid) can improve skin aging caused by sun exposure.


*Anti-inflammatory and bactericidal - topical application of Salicylic Acid (2-hydroxybenzoic acid) has different degrees of anti-inflammatory, astringent and antipruritic effects on seborrheic dermatitis, papulopustular rosacea, and folliculitis.
The anti-inflammatory effect of aspirin comes from the Salicylic Acid (2-hydroxybenzoic acid) formed after being decomposed in the body; and Salicylic Acid (2-hydroxybenzoic acid) has a certain broad-spectrum bactericidal ability and is effective against many bacteria and fungi.


*Whitening, Eliminate Pigmentation - Salicylic Acid (2-hydroxybenzoic acid) penetrates into pores, dissolves aging keratinocytes, lightens pigmentation and enhances skin cell metabolism.
Salicylic Acid (2-hydroxybenzoic acid) can dissolve the connection between the skin cutin, make the cuticle fall off, remove the excessively thick cuticle, promote epidermal metabolism, rejuvenate and whiten the skin, prevent the generation of acne marks, remove the acne marks that have already occurred, and can prevent UV damage and photoaging.



DIETARY SOURCES OF SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
Salicylic Acid (2-hydroxybenzoic acid) occurs in plants as free Salicylic Acid (2-hydroxybenzoic acid) and its carboxylated esters and phenolic glycosides.
Several studies suggest that humans metabolize Salicylic Acid (2-hydroxybenzoic acid) in measurable quantities from these plants.
High-salicylate beverages and foods include beer, coffee, tea, numerous fruits and vegetables, sweet potato, nuts, and olive oil. Meat, poultry, fish, eggs, dairy products, sugar, breads and cereals have low salicylate content.
Some people with sensitivity to dietary salicylates may have symptoms of allergic reaction, such as bronchial asthma, rhinitis, gastrointestinal disorders, or diarrhea, so may need to adopt a low-salicylate diet.



CHEMICAL PROPERTIES OF SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
*Formation of aspirin:
In the pharmaceutical industry, the most important reaction associated with the use of Salicylic Acid (2-hydroxybenzoic acid) is the production of aspirin i.e., acetylsalicylic acid.

Salicylic Acid (2-hydroxybenzoic acid) is one of the most commonly used analgesics and blood-thinning agent.
In this reaction, Salicylic Acid (2-hydroxybenzoic acid) is reacting with acetic anhydride.
It leads to the acetylation of the hydroxyl group present in the Salicylic Acid (2-hydroxybenzoic acid), thereby resulting in the production of acetylsalicylic acid i.e., aspirin.

Acetic acid is manufactured as a byproduct of this reaction.
This is also present as one of the impurities during large scale production of aspirin.
These impurities must be removed from the resulting product mixture by several refining processes.


*Esterification Reaction:
Since Salicylic Acid (2-hydroxybenzoic acid) is an organic acid, it undergoes a reaction with organic alcohol groups to produce a new organic chemical class alike ester.

When Salicylic Acid (2-hydroxybenzoic acid) is reacting with methanol in an acidic medium preferably sulphuric acid in the presence of heat, a dehydration reaction occurs with the loss of water −OH− ion.
This ion is lost from the carboxylic acid functional group present in the Salicylic Acid (2-hydroxybenzoic acid) molecule and the H+ ion is lost from the deprotonation of the methanol molecule, resulting in the formation of methyl salicylate (an ester).



METHODS OF PREPARATION OF SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
There are two most common methods in use for the preparation of Salicylic Acid (2-hydroxybenzoic acid) are as follows –

*From Phenol:
When phenol is reacted with sodium hydroxide, Salicylic Acid (2-hydroxybenzoic acid) forms sodium phenoxide.
Sodium phenoxide then undergoes distillation and dehydration.

This process is followed by a carboxylation reaction with carbon dioxide, which results in the formation of sodium salicylate i.e., salt of Salicylic Acid (2-hydroxybenzoic acid).
This salt then further reacted with an acid or hydronium ion or any species that denotes a proton to obtain the Salicylic Acid (2-hydroxybenzoic acid).


*From Methyl Salicylate:
Methyl salicylate also known as oil of wintergreen is commonly called analgesic in the pharmaceutical industry.
It is in use for the preparation of Salicylic Acid (2-hydroxybenzoic acid).

In this reaction, methyl salicylate is reacted with sodium hydroxide (NaOH) to lead to the formation of a sodium salt intermediate of Salicylic Acid (2-hydroxybenzoic acid).
This acid is named disodium salicylate, which upon undergoing further reaction with sulphuric acid leads to the formation of Salicylic Acid (2-hydroxybenzoic acid).



PHYSICAL PROPERTIES OF SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
Salicylic Acid (2-hydroxybenzoic acid) is a colourless, odourless and needle-shaped crystals at room temperature.
The taste of Salicylic Acid (2-hydroxybenzoic acid) is acrid.
The boiling point and melting point of Salicylic Acid (2-hydroxybenzoic acid) are 211oC and 315oC respectively.

The Salicylic Acid (2-hydroxybenzoic acid) molecule has two hydrogen bond donors and three hydrogen bond acceptors.
The flashpoint of Salicylic Acid (2-hydroxybenzoic acid) is 157oC.
Due to Salicylic Acid (2-hydroxybenzoic acid)'s lipophilic nature, its solubility in water is very poor i.e., 1.8 g/L at 25oC.

Salicylic Acid (2-hydroxybenzoic acid) is soluble in organic solvents like carbon tetrachloride, benzene, propanol, ethanol and acetone.
The density ofSalicylic Acid (2-hydroxybenzoic acid) is 1.44 at 20oC.
Salicylic Acid (2-hydroxybenzoic acid)'s vapour pressure is 8.2×105mmHg at 25oC.

Salicylic Acid (2-hydroxybenzoic acid) is a tendency to undergo discolouration when exposed to direct sunlight due to its photochemical degradation.
Salicylic Acid (2-hydroxybenzoic acid)'s heat of combustion is 3.026mj/mole at 25oC.
The pH of a saturated solution of Salicylic Acid (2-hydroxybenzoic acid) is 2.4.
Salicylic Acid (2-hydroxybenzoic acid)'s pka value i.e., dissociation constant is 2.97.



STRUCTURE OF SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
The structural formula of Salicylic Acid (2-hydroxybenzoic acid) is C6H4(OH)COOH.
The chemical formula of Salicylic Acid (2-hydroxybenzoic acid) can also be written as C7H6O3 in the condensed form.
The IUPAC name of Salicylic Acid (2-hydroxybenzoic acid) is 2-hydroxybenzoic acid.

Salicylic Acid (2-hydroxybenzoic acid) has a hydroxyl group i.e., -OH group attached at the ortho position with respect to the carboxylic acid.
This COOH group is present on the benzene ring.
The molecular weight or molar mass of Salicylic Acid (2-hydroxybenzoic acid) is 138.12 g/mol.

All carbon atoms present in the benzene ring of Salicylic Acid (2-hydroxybenzoic acid) are sp2 hybridized.
Salicylic Acid (2-hydroxybenzoic acid) forms an intramolecular hydrogen bond.
In an aqueous solution, Salicylic Acid (2-hydroxybenzoic acid) dissociates to lose a proton from the carboxylic acid.

The resulting carboxylate ion i.e., −COO− undergoes intermolecular interaction with the hydrogen atom of the hydroxyl group i.e., -OH.
Salicylic Acid (2-hydroxybenzoic acid) leads to the formation of an intramolecular hydrogen bond.



CHEMICAL SYNTHESIS OF SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
Commercial vendors prepare sodium salicylate by treating sodium phenolate (the sodium salt of phenol) with carbon dioxide at high pressure (100 atm) and high temperature (115 °C) – a method known as the Kolbe-Schmitt reaction. Acidifying the product with sulfuric acid gives Salicylic Acid (2-hydroxybenzoic acid):

At the laboratory scale, Salicylic Acid (2-hydroxybenzoic acid) can also be prepared by the hydrolysis of aspirin (acetylsalicylic acid) or methyl salicylate (oil of wintergreen) with a strong acid or base; these reactions reverse those chemicals' commercial syntheses.



REACTIONS OF SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
Upon heating, Salicylic Acid (2-hydroxybenzoic acid) converts to phenyl salicylate:
2 HOC6H4CO2H → C6H5O2C6H4OH + CO2 + H2O

Further heating gives xanthone.
Salicylic Acid (2-hydroxybenzoic acid) as its conjugate base is a chelating agent, with an affinity for iron(III).
Salicylic Acid (2-hydroxybenzoic acid) slowly degrades to phenol and carbon dioxide at 200–230 °C:
C6H4OH(CO2H) → C6H5OH + CO2



PRODUCTION AND CHEMICAL REACTIONS OF SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
Biosynthesis:
Salicylic Acid (2-hydroxybenzoic acid) is biosynthesized from the amino acid phenylalanine.
In Arabidopsis thaliana, Salicylic Acid (2-hydroxybenzoic acid) can be synthesized via a phenylalanine-independent pathway.



MECHANISM OF ACTION OF SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
Salicylic Acid (2-hydroxybenzoic acid) modulates COX-1 enzymatic activity to decrease the formation of pro-inflammatory prostaglandins.
Salicylate may competitively inhibit prostaglandin formation. Salicylate's antirheumatic (nonsteroidal anti-inflammatory) actions are a result of its analgesic and anti-inflammatory mechanisms.

Salicylic Acid (2-hydroxybenzoic acid), when applied to the skin surface, works by causing the cells of the epidermis to slough off more readily, preventing pores from clogging up, and allowing room for new cell growth.
Salicylic Acid (2-hydroxybenzoic acid) inhibits the oxidation of uridine-5-diphosphoglucose (UDPG) competitively with NADH and noncompetitively with UDPG.

Salicylic Acid (2-hydroxybenzoic acid) also competitively inhibits the transferring of glucuronyl group of uridine-5-phosphoglucuronic acid to the phenolic acceptor.
The wound-healing retardation action of salicylates is probably due mainly to its inhibitory action on mucopolysaccharide synthesis.



HISTORY OF SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
Willow has long been used for medicinal purposes.
Dioscorides, whose writings were highly influential for more than 1,500 years, used 'Itea' (which was possibly a species of willow) as a treatment for 'painful intestinal obstructions,' birth control, for 'those who spit blood,' to remove calluses and corns and, externally, as a 'warm pack for gout.'
William Turner, in 1597, repeated this, saying that willow bark, 'being burnt to ashes, and steeped in vinegar, takes away corns and other like risings in the feet and toes.'

Some of these cures may describe the action of Salicylic Acid (2-hydroxybenzoic acid), which can be derived from the salicin present in willow.
Salicylic Acid (2-hydroxybenzoic acid) was used in Europe and China to treat these conditions.
This remedy is mentioned in texts from Ancient Egypt, Sumer, and Assyria.

The Cherokee and other Native Americans use an infusion of the bark for fever and other medicinal purposes.
In 2014, archaeologists identified traces of Salicylic Acid (2-hydroxybenzoic acid) on seventh-century pottery fragments found in east-central Colorado.
The Reverend Edward Stone, a vicar from Chipping Norton, Oxfordshire, England, reported in 1763 that the bark of the willow was effective in reducing a fever.

An extract of willow bark, called salicin, after the Latin name for the white willow (Salix alba), was isolated and named by German chemist Johann Andreas Buchner in 1828.
A larger amount of the substance was isolated in 1829 by Henri Leroux, a French pharmacist.

Raffaele Piria, an Italian chemist, was able to convert the substance into a sugar and a second component, which on oxidation becomes Salicylic Acid (2-hydroxybenzoic acid).
Salicylic Acid (2-hydroxybenzoic acid) was also isolated from the herb meadowsweet (Filipendula ulmaria, formerly classified as Spiraea ulmaria) by German researchers in 1839.

Salicylic Acid (2-hydroxybenzoic acid)'s extract causes digestive problems such as gastric irritation, bleeding, diarrhea, and even death when consumed in high doses.
In 1874 the Scottish physician Thomas MacLagan experimented with salicin as a treatment for acute rheumatism, with considerable success, as he reported in The Lancet in 1876.

Meanwhile, German scientists tried sodium salicylate with less success and more severe side effects.
In 1979, salicylates were found to be involved in induced defenses of tobacco against tobacco mosaic virus.
In 1987, Salicylic Acid (2-hydroxybenzoic acid) was identified as the long-sought signal that causes thermogenic plants, such as the voodoo lily, Sauromatum guttatum, to produce heat.



SALICYLIC ACID (2-HYDROXYBENZOIC ACID), SIGNAL TRANSDUCTION:
A number of proteins have been identified that interact with SA in plants, especially Salicylic Acid (2-hydroxybenzoic acid) binding proteins (SABPs) and the NPR genes (nonexpressor of pathogenesis-related genes), which are putative receptors.
Salicylic Acid (2-hydroxybenzoic acid) is an effective inhibitor of COX-2 activity at concentrations far below those required to inhibit NF-κB (20 mg/mL) activation.

Salicylic Acid (2-hydroxybenzoic acid) inhibits prostaglandin E2 release when add together with interleukin 1β for 24 hr with an IC50 value of 5 μg/mL, an effect that is independent of NF-κB activation or COX-2 transcription or translation.
Salicylic Acid (2-hydroxybenzoic acid) acutely (30 min) also causes a concentration-dependent inhibition of COX-2 activity measured in the presence of 0, 1, or 10 μM exogenous arachidonic acid.

In contrast, when exogenous arachidonic acid is increased to 30 μM, Salicylic Acid (2-hydroxybenzoic acid) is a very weak inhibitor of COX-2 activity with an IC50 of >100 μg/mL.
When added together with IL-1β for 24 hr, Salicylic Acid (2-hydroxybenzoic acid) causes a concentration-dependent inhibition of PGE2 release with an apparent IC50 value of approximately 5 μg/mL.

The ability of Salicylic Acid (2-hydroxybenzoic acid) to directly inhibit COX-2 activity in A549 cells is tested after a 30-min exposure period, followed by the addition of different concentrations of exogenous arachidonic acid (1, 10, and 30 μM).

Salicylic Acid (2-hydroxybenzoic acid) causes a concentration-dependent inhibition of COX-2 activity in the absence of added arachidonic acid or in the presence of 1 or 10 μM exogenous substrate with an apparent IC50 value of approximately 5 μg/mL.

However, when the same experiments are performed using 30 μM arachidonic acid, Salicylic Acid (2-hydroxybenzoic acid) is an ineffective inhibitor of COX-2 activity, with an apparent IC50 value of more than 100 μg/mL, and achieves a maximal inhibition of less than 50%.



SALICYLIC ACID (2-HYDROXYBENZOIC ACID), PLANT HORMONE
Salicylic Acid (2-hydroxybenzoic acid) is a phenolic phytohormone, and is found in plants with roles in plant growth and development, photosynthesis, transpiration, and ion uptake and transport.

Salicylic Acid (2-hydroxybenzoic acid) is involved in endogenous signaling, mediating plant defense against pathogens.
Salicylic Acid (2-hydroxybenzoic acid) plays a role in the resistance to pathogens (i.e. systemic acquired resistance) by inducing the production of pathogenesis-related proteins and other defensive metabolites.

Salicylic Acid (2-hydroxybenzoic acid)'s defense signaling role is most clearly demonstrated by experiments which do away with it: Delaney et al. 1994, Gaffney et al. 1993, Lawton et al. 1995, and Vernooij et al. 1994 each use Nicotiana tabacum or Arabidopsis expressing nahG, for salicylate hydroxylase.
Pathogen inoculation did not produce the customarily high Salicylic Acid (2-hydroxybenzoic acid) levels, SAR was not produced, and no PR genes were expressed in systemic leaves. Indeed, the subjects were more susceptible to virulent – and even normally avirulent – pathogens.

Exogenously, Salicylic Acid (2-hydroxybenzoic acid) can aid plant development via enhanced seed germination, bud flowering, and fruit ripening, though too high of a concentration of Salicylic Acid (2-hydroxybenzoic acid) can negatively regulate these developmental processes.

The volatile methyl ester of Salicylic Acid (2-hydroxybenzoic acid), methyl salicylate, can also diffuse through the air, facilitating plant-plant communication.
Methyl salicylate is taken up by the stomata of the nearby plant, where it can induce an immune response after being converted back to Salicylic Acid (2-hydroxybenzoic acid).



ALTERNATIVE PARENTS OF SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
*Benzoic acids
*Benzoyl derivatives
*1-hydroxy-4-unsubstituted benzenoids
*1-hydroxy-2-unsubstituted benzenoids
*Vinylogous acids
*Monocarboxylic acids and derivatives
*Carboxylic acids
*Organooxygen compounds
*Organic oxides
*Hydrocarbon derivatives



SUBSTITUENTS OF SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
*Salicylic acid
*Benzoic acid
*Benzoyl
*1-hydroxy-4-unsubstituted benzenoid
*1-hydroxy-2-unsubstituted benzenoid
*Phenol
*Vinylogous acid
*Monocarboxylic acid or derivatives
*Carboxylic acid
*Carboxylic acid derivative
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Organooxygen compound
*Aromatic homomonocyclic compound



PHYSICAL and CHEMICAL PROPERTIES of SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
Formula : C7H6O3
Molecular weight : 138,12 g/mol
CAS-No. : 69-72-7
EC-No. : 200-712-3
Physical state: powdercrystalline
Color: white
Odor: odorless
Melting point/freezing point:
Melting point/range: 158 - 160 °C
Initial boiling point and boiling range: 211 °C at 27 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Lower explosion limit: 1,1 %(V)
Flash point 157 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 2,4 at 20 °C

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water:
log Pow: 2,25 at 25 °C - Bioaccumulation is not expected.
Vapor pressure: 1 hPa at 114 °C
Density: 1,44 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Chemical Name : 2 – Hydroxybenzoic Acid
Molecular Formula : C7H6O3
Molecular Weight : 138.1
Description : White / colourless, crystalline powder / acicular crystals

CAS No. : 69-72-7
CAS: 69-72-7
MF: C7H6O3
MW: 138.12
EINECS: 200-712-3
Mol File: 69-72-7.mol
Salicylic acid: Chemical Properties
Melting point: 158-161 °C(lit.)
Boiling point: 211 °C(lit.)
density: 1.44
vapor density: 4.8 (vs air)
vapor pressure: 1 mm Hg ( 114 °C)
refractive index: 1,565
FEMA: 3985 | 2-HYDROXYBENZOIC ACID
Fp: 157 °C
storage temp.: 2-8°C
solubility: ethanol: 1 M at 20 °C, clear, colorless
pka: 2.98(at 25℃)

form: Solid
color: White to off-white
PH Range: Non0 uorescence (2.5) to dark blue 0 uorescence (4.0)
Odor: at 100.00 %. faint phenolic nutty
PH: 3.21(1 mM solution);2.57(10 mM solution);2.02(100 mM solution);
Odor Type: nutty
Water Solubility: 1.8 g/L (20 ºC)
Sensitive: Light Sensitive
λmax: 210nm, 234nm, 303nm
Merck: 148,332
JECFA Number: 958
Sublimation: 70 ºC
BRN: 774890
Stability: Stable.
InChIKey: YGSDEFSMJLZEOE-UHFFFAOYSA-N

LogP: 2.01
CAS DataBase Reference: 69-72-7(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 2-hydroxy-(69-72-7)
EPA Substance Registry System: Salicylic acid (69-72-7)
IUPAC Name: 2-hydroxybenzoic acid
Molecular Weight: 138.12
Molecular Formula: C7H6O3
Canonical SMILES: C1=CC=C(C(=C1)C(=O)O)O
InChI: InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChIKey: YGSDEFSMJLZEOE-UHFFFAOYSA-N
Boiling Point: 211 ℃ (20 mmHg)
Melting Point: 154-156 ℃
Flash Point: 157ºC
Purity: > 98 %
Density: 1.44 g/cm3

Solubility: Solubility (weight percent):
carbon tetrachloride 0.262 (25 °C);
benzene 0.775 (25 °C); propanol 27.36 (21 °C);
absolute ethanol 34.87 (21 °C); acetone 396 (23 °C)
Appearance: White poder
Storage: Store at RT.
EINECS: 200-712-3
Hazard Codes: Xn
HS Code: 2918211000
Log P: 1.09040
MDL: MFCD00002439
pH: pH of saturated solution: 2.4
PSA: 57.53
Quality Standard: Enterprise Standard
Refractive Index: 1.565
Risk Statements: R22; R36/37/38; R41

RTECS: VO0525000
Safety Statements: S26-S37/39
Stability: Stable.
Vapor Density: 4.8
Vapor Pressure: 1 mm Hg ( 114 °C)
Odour: Almost Odourless.
Melting Range: 158.5°C to 161.0°C.
Appearance of Solution/
Clarity & Colour of Solution: Passes test as per B.P./I.P.
Heavy Metals: 20 ppm (max)
Sulphated Ash/Residue on Ignition: 0.1% w/w (I.P./B.P.Limit) / 0.05% w/w (U.S.P. Limit)
Chloride: 125 ppm (max.) I.P./100 ppm (max.) B.P.
Sulphate: 0.02% (max.) I.P./140 ppm U.S.P.
Related Substance: Complies with the B.P. test.
Loss of Drying: 0.5% (max.) B.P.

Iron: 2 ppm (max.) I.P.
Molecular Weight: 138.12 g/mol
XLogP3: 2.3
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 1
Exact Mass: 138.031694049 g/mol
Monoisotopic Mass: 138.031694049 g/mol
Topological Polar Surface Area: 57.5Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 133
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0

Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
CAS number: 69-72-7
EC number: 200-712-3
Hill Formula: C₇H₆O₃
Chemical formula: HOC₆H₄COOH
Molar Mass: 138.12 g/mol
HS Code: 2918 21 10
Boiling point: 211 °C (1013 hPa)
Density: 1.44 g/cm3 (20 °C)
Flash point: 157 °C
Ignition temperature: 500 °C
Melting Point: 158 - 160 °C
pH value: 2.4 (H₂O, 20 °C) (saturated solution)
Vapor pressure: 1 hPa (114 °C)
Bulk density: 400 - 500 kg/m3
Solubility: 2 g/l
Chemical formula: C7H6O3
Molar mass: 138.122 g/mol
Appearance: Colorless to white crystals

Odor: Odorless
Density: 1.443 g/cm3 (20 °C)
Melting point: 158.6 °C (317.5 °F; 431.8 K)
Boiling point: 211 °C (412 °F; 484 K) at 20 mmHg
Sublimation conditions: Sublimes at 76 °C
Solubility in water:
1.24 g/L (0 °C)
2.48 g/L (25 °C)
4.14 g/L (40 °C)
17.41 g/L (75 °C)
77.79 g/L (100 °C)
Solubility: Soluble in ether, CCl4, benzene, propanol,
acetone, ethanol, oil of turpentine, toluene
Solubility in benzene:
0.46 g/100 g (11.7 °C)
0.775 g/100 g (25 °C)
0.991 g/100 g (30.5 °C)
2.38 g/100 g (49.4 °C)
4.4 g/100 g (64.2 °C)

Solubility in chloroform:
2.22 g/100 mL (25 °C)
2.31 g/100 mL (30.5 °C)
Solubility in methanol:
40.67 g/100 g (−3 °C)
62.48 g/100 g (21 °C)
Solubility in olive oil: 2.43 g/100 g (23 °C)
Solubility in acetone: 39.6 g/100 g (23 °C)
log P: 2.26
Vapor pressure: 10.93 mPa
Acidity (pKa):
2.97 (25 °C)
13.82 (20 °C)
UV-vis (λmax): 210 nm, 234 nm, 303 nm (4 mg/dL in ethanol)
Magnetic susceptibility (χ): −72.23·10−6 cm3/mol
Refractive index (nD): 1.565 (20 °C)
Dipole moment: 2.65 D

Thermochemistry:
Std enthalpy of formation (ΔfH⦵298): −589.9 kJ/mol
Std enthalpy of combustion (ΔcH⦵298): -3.025 MJ/mol
CAS: 69-72-7
MF: C7H6O3
MW: 138.12
EINECS: 200-712-3
Mol File: 69-72-7.mol
Salicylic acid Chemical Properties
Melting point: 158-161 °C(lit.)
Boiling point: 211 °C(lit.)
density: 1.44
vapor density: 4.8 (vs air)
vapor pressure: 1 mm Hg ( 114 °C)
refractive index: 1,565
FEMA: 3985 | 2-HYDROXYBENZOIC ACID
Fp: 157 °C

storage temp.: 2-8°C
solubility: ethanol: 1 M at 20 °C, clear, colorless
pka: 2.98(at 25℃)
form: Solid
color: White to off-white
PH Range: Non0 uorescence (2.5) to dark blue 0 uorescence (4.0)
Odor: at 100.00 %. faint phenolic nutty
PH: 3.21(1 mM solution);2.57(10 mM solution);2.02(100 mM solution);
Odor Type: nutty
Water Solubility: 1.8 g/L (20 ºC)
Sensitive: Light Sensitive
λmax: 210nm, 234nm, 303nm
Merck: 148,332
JECFA Number: 958
Sublimation: 70 ºC
BRN: 774890
Stability:: Stable. S
ubstances to be avoided include oxidizing agents, strong bases, iodine, fluorine.
Sensitive to light.

InChIKey: YGSDEFSMJLZEOE-UHFFFAOYSA-N
LogP: 2.01
CAS DataBase Reference: 69-72-7(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 2-hydroxy-(69-72-7)
EPA Substance Registry System: Salicylic acid (69-72-7)
IUPAC: SALICYLICACID
CAS Number: 69-72-7
Molecular Weight: 138.122
Formula: C7H6O3
SMILES: OC(=O)C1=C(O)C=CC=C1
Preferred IUPAC Name: 2-HYDROXYBENZOIC ACID
InChIKey: InChIKey=YGSDEFSMJLZEOE-UHFFFAOYSA-N
Melting Point: 158°C
Color: White
pH: 3.6
Boiling Point: 211°C
Formula Weight: 138.12g/mol
Vapor Pressure: 0.3mbar 95
Physical Form: Solid

CAS number: 69-72-7
EC number: 200-712-3
Hill Formula: C₇H₆O₃
Chemical formula: HOC₆H₄COOH
Molar Mass: 138.12 g/mol
HS Code: 2918 21 10
Boiling point: 211 °C (1013 hPa)
Density: 1.44 g/cm3 (20 °C)
Flash point: 157 °C
Ignition temperature: 500 °C
Melting Point: 158 - 160 °C
pH value: 2.4 (H₂O, 20 °C) (saturated solution)
Vapor pressure: 1 hPa (114 °C)
Bulk density: 400 - 500 kg/m3
Solubility: 2 g/l
CAS number: 69-72-7
Weight Average: 138.1207
Monoisotopic: 138.031694058
InChI Key: YGSDEFSMJLZEOE-UHFFFAOYSA-N

InChI: InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
IUPAC Name: 2-hydroxybenzoic acid
Traditional IUPAC Name: salicylic
Chemical Formula: C7H6O3
SMILES: OC(=O)C1=CC=CC=C1O
Appearance: white powder (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 158.00 to 161.00 °C. @ 760.00 mm Hg
Boiling Point: 211.00 °C. @ 20.00 mm Hg
Boiling Point: 336.00 to 337.00 °C. @ 760.00 mm Hg
Vapor Pressure: 1.000000 mmHg @ 114.00 °C.
Vapor Density: 4.8 ( Air = 1 )
Flash Point: > 212.00 °F. TCC ( > 100.00 °C. )
logP (o/w): 2.260
Soluble in: alcohol
water, 3808 mg/L @ 25 °C (est)
water, 2240 mg/L @ 25 °C (exp)



FIRST AID MEASURES of SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Store at Room Temperature.
Light sensitive



STABILITY and REACTIVITY of SALICYLIC ACID (2-HYDROXYBENZOIC ACID):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available



SALICYLIC ACID (CAS 69-72-7)
Salicylic Acid (Cas 69-72-7) is an organic compound with the formula HOC6H4COOH.
Salicylic Acid (Cas 69-72-7) is perfume material, used for the preparation of methyl salicylate, salicylic acid ethyl ester; food preservatives, its sodium Salt is mostly used, now a number of countries have been banned; methyl salicylate can be used as oral cleaning agents, such as toothpaste flavor.
Salicylic Acid (Cas 69-72-7) has sterilization ability, 2.5% alcohol solution (called spiritus) is used as a topical medicine in the treatment of tinea manus and tinea pedis, also can be made into ointment.

CAS Number: 69-72-7
Molecular Formula: C7H6O3
Molecular Weight: 138.12
EINECS Number: 200-712-3

Synonyms: salicylic acid, 2-Hydroxybenzoic acid, 69-72-7, o-hydroxybenzoic acid, 2-Carboxyphenol, o-Carboxyphenol, Rutranex, Salonil, Retarder, W, Keralyt, Duoplant, Freezone, Saligel, Ionil, Psoriacid-S-stif, Benzoic acid, 2-hydroxy-, Stri-De, Salicylic acid soap, Salicylic acid collodion, Verrugon, Phenol-2-carboxylic aciD, , Acidum salicylicum, Trans-Ver-Sal, Orthohydroxybenzoic acid, 2-Hydroxybenzenecarboxylic acid, Acidosalicilico, IonilPlus, Salicylicacid,tech., Kyselinasalicylova, Clearawaywartremover, Duofil, Domerine, Sebucare, Duofilm, Sebulex, Salicyclic acid, Ionil, plus, Dr. Scholl's corn remover, Kyselina salicylova [Czech], Dr. Scholl's callus removers, Dr. Scholl's wart remover kit, Kyselina 2-hydroxybenzoova, Occlusal, Acido salicilico [Italian], Advanced pain relief corn removers, Caswell No. 731, 2-hydroxy-benzoic acid, Kyselina 2-hydroxybenzoova [Czech], Advanced pain relief callus removers, Acido o-idrossibenzoico [Italian], NSC 180, Salicylicacid&SulfurSoap, CCRIS6714, HSDB672, AI302407, UNIIO414PZ4LPZ, MFCD00002439, EPAPestiideChemicalCode076602, BRN0774890, CHEBI:16914, CHEMBL424, O414PZ4LPZ acid inclusion complex, K 537, NSC-180, ATA fraction 10, ammonium salt, NCGC00159447-05, SMR000059163, Mediplast pads, Salicylic acid, 9 +%, Akurza Lotion, Hydrisalic Gel, Akurza Cream, Salex Lotion, Salex Cream, DSSTox_CID_6368, DuoPlant Gel, DHS Sal Shampoo, DSSTox_RID_78106, P&S Shampoo, DSSTox_GSID_26368, Salicylic acid [USAN:JAN], Acido o-idrossibenzoico, Durasal, Salicylic acid, 99+%, ACS reagent, salicylicum acidum, CAS-69- 72-7, Propa pH Peel-Off Acne Mask, NSC629474, phenol derivative, 7, Salicylic acid (TN), Benzoic acid, 2-hydroxy-, ion(1-), EINECS 200-712-3, Salicylic acid [USP:JAN], Azurechelin, Salicylic acid (6CI,8CI), Anti-blemish, Salicylic acid rs, hydroxy-benzoic acid, ortho-salicylic acid, CMC_13852, Fostex (Salt/Mix), Pernox (Salt/Mix), Duofilm Wart Remover, Phenol-2-carboxylate, Duofilm (Salt/Mix), Salicylic Acid,(S), Sebulex (Salt/Mix), 2-hydroxobenzoic acid, Domerine (Salt/Mix), Sebucare (Salt/Mix), 2-Hydroxybenzoate, I, Natural Salicylic Acid, ohydroxybenzoicacid, 2hydroxybenzoicacid, Spectrum_ 00948, Salicylicacid,medicinal, ACMC-1AZI, Opera_ID_582, Sulfasalazine Impurity H, Salicylic acid ACS grade, [O]C(=O)c1ccccc1O, WLN: QVR BQ, Benzoic acid, o-hydroxy-, Bazuka Extra Strength Gel, 2-Hydroxybenzenecarboxylate, bmse000252, Epitope ID:124929, RetarderSAX(Salt/Mix), UPCMLD-DP126, E200-712- 3, SCHEMBL1967, Oprea1_040343, KBioSS_001428, ARONIS27188, BIDD:ER0602, DivK1c_000301, Salicylic acid (JP17/USP), 2-Hydroxybenzoic Acid, Natural, FEMA3985, GTPL4306, SGCUT00012, ZINC1554, Salicylic acid, >=99%, FG, Salicylic acid, LR, >=99%, component of Tinver (Salt/Mix), DTXSID7026368, FEMA NO. 3985, UPCMLD-DP126:001, BDBM26193, component of Keralyt (Salt/Mix), KBio1_000301, KBio2_001428, KBio2_003996, KBio2_006564, Alpha/BetaHydroxyAcids(GlycolicAcid,SalicylicAcid), E9A559BE383B4F83BC023031D03D558A, NINDS_000301 02, NCGC00159447-04, NCGC00159447-06, NCGC00257065-01, NCGC00259022-01, AK112186, BP-12826, KSC-11-207-4, Lamivudine related compound salicylic acid, Salicylic acid & Sulfur Soap (Salt/Mix), Salicylic acid, ACS reagent, >=99.0%, Salicylic acid, plant cell culture tested, Salicylic acid, ReagentPlus(R), >=99%, SC-18305, TS-03583, Salicylic Acid 1.0 mg/ml , SBI0051510.P003, FT0645123, FT-0674502, FT-0674503, Salicylic acid, tested according to Ph.Eur., ST51046715, Salicylic acid, SAJ first grade, >=99.0%, Salicylic acid, Vetec(TM)reagentgrade98%, 44642EP2281819A1, 44642EP2292619A1, 44642EP2305659A1, 44642EP2311818A1, AB00489876_15, ENZOICACID,2HYDROXYSALICYLICACID, Salicylicacid,p of Solarcaine first aid spray (Salt/Mix), J-509667, component of Fostex medicated bar and cream (Salt/Mix), F2191-0216, Salicylic acid, certified reference material, TraceCERT(R), UNII-I3P9R8317T component YGSDEFSMJLZEOE-UHFFFAOYSA-N, Salicylic acid, British Pharmacopoeia (BP) Reference Standard, Salicylic acid, European Pharmacopoeia (EP) Reference Standard, Salicylic acid, United States Pharmacopeia (USP) Reference Standard, Salicylic acid, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Salicylic acid, Pharmaceutical Secondary Standard, Certified Reference Material, 8052-31-1, Salicylic acid, meets analytical specification of Ph. 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Salicylic Acid (Cas 69-72-7) can be used for food preservative or preservatives, also can be used for the preparation of toothpaste, mouthwash.
Salicylic Acid (Cas 69-72-7) has antipyretic and analgesic effects, can cure rheumatism and so on.
Salicylic Acid (Cas 69-72-7)'s all esters can be used as drug and spices.

Salicylic Acid (Cas 69-72-7) has pleasant aromas of holly, is used for the preparation of perfume and soap flavor.
Salicylic Acid (Cas 69-72-7) is a plant hormone, and has been listed by the EPA Toxic Substances Control Act (TSCA) Chemical Substance Inventory as an experimental teratogen.
The methyl salicylate is coated on the skin, can penetrate into the muscle and let out of Salicylic Acid (Cas 69-72-7) to release local pain, so it also can be used for the treatment of pain, contusion, sprain and other medication.

Salicylic Acid (Cas 69-72-7) can be acetylated to the aspirin.
Salicylic Acid (Cas 69-72-7) is a white powder with an acrid taste that is stable in air but gradually discolored by light.
Soluble in acetone, oil of turpentine, alcohol, ether,benzene; slightly soluble in water,and combustible.

Derived by reacting a hot solution of sodium phenolate with carbon dioxide and acidifying the sodium salt thus formed.
Salicylic Acid (Cas 69-72-7) is used in the manufacture of aspirin and salicylates, resins, dyestuff intermediate, prevulcanization inhibitor, analytical reagent,and fungicide.
Salicylic Acid (Cas 69-72-7) is a white solid first isolated from the bark of willow trees (Salix spp.), from which it gets its name.

Salicylic Acid (Cas 69-72-7) also occurs as the free acid or its esters in many plant species.
Salicylic Acid (Cas 69-72-7) is a mono hydroxy benzoic acid, a type of phenolic acid and a beta hydroxy acid.
This colorless crystalline organic acid is widely used in organic synthesis and functions as a plant hormone.

Salicylic Acid (Cas 69-72-7) is derived from the metabolism of salicin.
Salicylic Acid (Cas 69-72-7) is also known as 2- hydroxybenzoic acid.
Salicylic Acid (Cas 69-72-7) is poorly soluble in water (2 g / L at 20 °C).

Aspirin (acetyl salicylic acid or ASA) can be prepared by the esterification of the phenolic hydroxyl group of Salicylic Acid (Cas 69-72-7) with the acetyl group from acetic anhydride or acetyl chloride.
Salicylic Acid (Cas 69-72-7) is absolutely soluble in ethanol, soluble in ether and chloroform, slightly soluble in water and anhydrous ether.
Salicylic Acid (Cas 69-72-7) stable at room temperature, discomposes into phenol and carbon dioxide after rapidly heated.

Salicylic Acid (Cas 69-72-7) is biosynthesized from the amino acid phenylalanine.
In Arabidopsis thaliana, Salicylic Acid (Cas 69-72-7) can be synthesized via a phenylalanine-independent pathway.
Salicylic Acid (Cas 69-72-7) is a phenolic phytohormone, and is found in plants with roles in plant growth and development, photosynthesis, transpiration, and ion uptake and transport.

Salicylic Acid (Cas 69-72-7) is a beta hydroxy acid that also sloughs dead cell buildup within the follicle, acts as a mild antibacterial, and has soothing properties.
Salicylic Acid (Cas 69-72-7) is regarded to be less irritating than benzoyl peroxide and has less allergy potential, but it is also less aggressive in treating acne.
Salicylic Acid (Cas 69-72-7) is often used for treating milder forms of acne.

The concentration in OTC drugs is limited to 2 percent.
Salicylic Acid (Cas 69-72-7) is also used as a performance ingredient exfoliant in smaller concentrations, without making a drug claim.
Salicylic Acid (Cas 69-72-7) as a medication is commonly used to remove the outer layer of the skin.

Salicylic Acid (Cas 69-72-7) is involved in endogenous signaling, mediating plant defense against pathogens.
Salicylic Acid (Cas 69-72-7) plays a role in the resistance to pathogens (i.e. systemic acquired resistance) by inducing the production of pathogenesis-related proteins and other defensive metabolites.
Salicylic Acid (Cas 69-72-7)'s defense signaling role is most clearly demonstrated by experiments which do away with it: Delaney et al. 1994, Gaffney et al. 1993, Lawton et al. 1995, and Vernooij et al. 1994 each use

Nicotiana tabacum or Arabidopsis expressing nahG, for salicylate hydroxylase.
Pathogen inoculation did not produce the customarily high Salicylic Acid (Cas 69-72-7) levels, SAR was not produced, and no PR genes were expressed in systemic leaves.
Indeed, the subjects were more susceptible to virulent – and even normally avirulent – pathogens.

Salicylic Acid (Cas 69-72-7) is a beta-hydroxy acid with keratolytic and antiinflammatory activity.
Salicylic Acid (Cas 69-72-7) helps dissolve the top layer of stratum corneum cells, improving the look and feel of the skin.
Salicylic Acid (Cas 69-72-7) is an effective ingredient in acne products and as such is widely used in acne soaps and lotions.

Because Salicylic Acid (Cas 69-72-7) is lipid soluble, it can more easily reduce sebaceous follicle blockage by penetrating the pores and exfoliating the cellular buildup.
Salicylic Acid (Cas 69-72-7) is antimicrobial, anti-septic, enhances the activity of preservatives, and can be used to adjust the pH of products.
For the treatment of aging skin, it appears to help improve skin wrinkles, roughness, and tone.

Salicylic Acid (Cas 69-72-7) is a useful ingredient for products formulated to treat psoriasis, callouses, corns, and warts-cases where there is a buildup of dead skin cells.
When applied topically, Salicylic Acid (Cas 69-72-7) is reported to penetrate 3 to 4 mm into the epidermis.
Salicylic Acid (Cas 69-72-7) can convert to copper salicylate, a powerful anti-inflammatory.

Salicylic Acid (Cas 69-72-7) can be used for food preservative or preservatives, also can be used for the preparation of toothpaste, mouthwash.
Salicylic Acid (Cas 69-72-7) has antipyretic and analgesic effects, can cure rheumatism and so on.
Salicylic Acid (Cas 69-72-7)'s all esters can be used as drug and spices.

Salicylic Acid (Cas 69-72-7) has pleasant aromas of holly, is used for the preparation of perfume and soap flavor.
The methyl salicylate is coated on the skin, can penetrate into the muscle and let out of Salicylic Acid (Cas 69-72-7) to release local pain, so it also can be used for the treatment of pain, contusion, sprain and other medication.
Isoamyl salicylate has orchid aroma, Salicylic Acid (Cas 69-72-7) has weak ester aroma, both can prepare perfume or soap flavor.

The common name of phenyl salicylate is Salo, was hydrolyzed into phenol and Salicylic Acid (Cas 69-72-7) in the intestine , is a kind of effective enteral preservatives.
Another Kind drug related to Salicylic Acid (Cas 69-72-7) is para amino2-Hydroxybenzoic acid (salicylic acid) (PAS, see "Para amino salicylic acid), Its sodium and calcium salts are used as anti TB drugs for acute exudative pulmonary tuberculosis (TB) and mucosal tuberculosis, is a weak antimicrobial drug, the effect is only 2% of streptomycin, often combined with streptomycin and isoniazid , in order to enhance the curative effect.

Salicylic Acid (Cas 69-72-7) can be acetylated to the aspirin
Salicylic Acid (Cas 69-72-7) is a natural product extract from Willow bark, well known as an antiinflammatory and antinociceptive agent and a close structural relative to acetylsalicylic acid (aspirin).
Salicylic Acid (Cas 69-72-7) is a ubiquitous plant hormone with many regulatory functions involved in local disease resistance mechanisms and systemic acquired resistance.

The antiinflammatory and antinociceptive effects produced by Salicylic Acid (Cas 69-72-7) and its derivatives in animals are due to inhibition of COX-1 and COX-2 (cyclooxygenase) enzyme activity and suppression of prostaglandin biosynthesis.
Salicylic Acid (Cas 69-72-7) is also of interest as a starting material for the organic synthesis of more elaborate COX suppressors and other chemical structures.
Salicylic Acid (Cas 69-72-7) is often used in skincare products, such as cleansers, toners, and spot treatments, due to its ability to exfoliate the skin.

Salicylic Acid (Cas 69-72-7) penetrates into the pores and helps to remove dead skin cells, excess oil, and debris, making it effective for treating acne and improving overall skin texture.
Salicylic Acid (Cas 69-72-7) is particularly beneficial for those with acne-prone skin.
Salicylic Acid (Cas 69-72-7) works by dissolving the substance that causes skin cells to stick together, promoting the shedding of dead skin cells.

Salicylic Acid (Cas 69-72-7) is used at high concentrations, Salicylic Acid (Cas 69-72-7) may cause skin redness and rashes.
This is a naturally occurring organic acid, related to aspirin.
Salicylic Acid (Cas 69-72-7) is found in some plants, particularly the leaves of wintergreen, willow bark, and the bark of sweet birch.

Salicylic Acid (Cas 69-72-7) is also synthetically manufactured.
Salicylic Acid (Cas 69-72-7) causes a concentration-dependent inhibition of COX-2 activity in the absence of added arachidonic acid or in the presence of 1 or 10 μM exogenous substrate with an apparent IC50 value of approximately 5 μg/mL.
However, when the same experiments are performed using 30 μM arachidonic acid, Salicylic Acid (Cas 69-72-7) is an ineffective inhibitor of COX-2 activity, with an apparent IC50 value of more than 100 μg/mL, and achieves a maximal inhibition of less than 50%.

Salicylic Acid (Cas 69-72-7) is lipophilic monohydroxybenzoic acid.
Salicylic Acid (Cas 69-72-7) a type of phenolic acid and a beta-hydroxy acid (BHA).
Beta hydroxy acid is found as a natural compound in plants.

This colourless crystalline organic acid is broadly in use in organic synthesis.
Salicylic Acid (Cas 69-72-7) is derived from the metabolism of salicin.
Salicylic Acid (Cas 69-72-7) is a crystalline organic carboxylic acid and has keratolytic, bacteriostatic and fungicidal properties.

Salicylic Acid (Cas 69-72-7) is poisonous to our body when consumed in large.
Salicylic Acid (Cas 69-72-7) can be in use as an antiseptic and as a food preservative when consumed in small quantities.
Salicylic Acid (Cas 69-72-7) is a precursor to acetylsalicylic acid, commonly known as aspirin, which is used for its analgesic (pain-relieving), anti-inflammatory, and antipyretic (fever-reducing) properties.

Individuals with known allergies to aspirin (acetylsalicylic acid) should exercise caution when using products containing Salicylic Acid (Cas 69-72-7).
Allergic reactions can include redness, itching, or swelling.
If such reactions occur, discontinuing use and seeking medical advice is recommended.

Salicylic Acid (Cas 69-72-7) is an important organic synthetic raw material, widely used in medicine, pesticides, dyes, rubber, food, and perfumes.
In the pharmaceutical industry, the main drug productions of Salicylic Acid (Cas 69-72-7) are sodium salicylate, wintergreen oil (methyl salicylate), aspirin (acetylsalicylic acid), and Salicylic Acid (Cas 69-72-7) amine, phenyl salicylate.
In the dye industry, Salicylic Acid (Cas 69-72-7) is used to producepure morda yellow , direct yellow 3GN, direct yellow GR, direct brown 3GN, acid mordant brown G, acid mordant yellow GG, acid yellow dye complex.

In pesticide production, Salicylic Acid (Cas 69-72-7) is used for the synthesis of organic phosphorus pesticide Isocarbophos, intermediate isopropyl salicylate isofenphos methyl and Rodenticide warfarin, coumatetralyl intermediate 4-hydroxycoumarin.
In rubber industry, Salicylic Acid (Cas 69-72-7) is used as anti scorching agent and production of ultraviolet absorbent and foaming agent.
Salicylic Acid (Cas 69-72-7) is perfume material, used for the preparation of methyl salicylate, Salicylic Acid (Cas 69-72-7) ethyl ester; food preservatives, its sodium Salt is mostly used, now a number of countries have been banned; methyl salicylate can be used as oral cleaning agents, such as toothpaste flavor.

Salicylic Acid (Cas 69-72-7) has sterilization ability, 2.5% alcohol solution (called spiritus) is used as a topical medicine in the treatment of tinea manus and tinea pedis, also can be made into ointment.
Salicylic Acid (Cas 69-72-7) has a carboxyl group attached to it i.e., COOH.
Salicylic Acid (Cas 69-72-7) is odourless and is colourless.

Salicylic Acid (Cas 69-72-7) is an organic compound with the formula HOC6H4COOH.
Salicylic Acid (Cas 69-72-7) is a precursor to and a metabolite of aspirin (acetylsalicylic acid).
Salicylic Acid (Cas 69-72-7) is a plant hormone, and has been listed by the EPA Toxic Substances Control Act (TSCA) Chemical Substance Inventory as an experimental teratogen.

The name is from Latin salix for willow tree, from which it was initially identified and derived.
Salicylic Acid (Cas 69-72-7) is an ingredient in some anti-acne products.
Salts and esters of Salicylic Acid (Cas 69-72-7) are known as salicylates.

Salicylic Acid (Cas 69-72-7) is an organic compound with the formula HOC6H4CO2H.
A colorless, bitter-tasting solid, Salicylic Acid (Cas 69-72-7) is a precursor to and a metabolite of aspirin (acetylsalicylic acid).
Salicylic Acid (Cas 69-72-7) is a plant hormone and has been listed by the EPA Toxic Substances Control Act (TSCA) Chemical Substance Inventory as an experimental teratogen.

Salicylic Acid (Cas 69-72-7) is an effective inhibitor of COX-2 activity at concentrations far below those required to inhibit NF-κB (20 mg/mL) activation.
Salicylic Acid (Cas 69-72-7) inhibits prostaglandin E2 release when add together with interleukin 1β for 24 hr with an IC50 value of 5 μg/mL, an effect that is independent of NF-κB activation or COX-2 transcription or translation.
Salicylic Acid (Cas 69-72-7) acutely (30 min) also causes a concentration-dependent inhibition of COX-2 activity measured in the presence of 0, 1, or 10 μM exogenous arachidonic acid.

Salicylic Acid (Cas 69-72-7) is an ingredient in some anti-acne products.
Salts and esters of Salicylic Acid (Cas 69-72-7) are known as salicylates.
Salicylic Acid (Cas 69-72-7) is a white, crystalline powder with the chemical formula C7H6O3.

Salicylic Acid (Cas 69-72-7) is chemical structure consists of a benzene ring with a hydroxyl group (-OH) and a carboxyl group (-COOH) attached.
This structure is responsible for its exfoliating and anti-inflammatory properties.
Salicylic Acid (Cas 69-72-7) works by softening and breaking down keratin, a protein that forms part of the skin structure.

This keratolytic action helps to unclog pores and prevent the formation of comedones (blackheads and whiteheads).
Salicylic Acid (Cas 69-72-7) also has anti-inflammatory effects, which can reduce the redness and swelling associated with acne.
Salicylic Acid (Cas 69-72-7) is commonly found in over-the-counter skincare products at concentrations ranging from 0.5% to 2%.

Higher concentrations may be used in professional treatments, but it's important to follow product instructions to avoid overuse and potential irritation.
Salicylic Acid (Cas 69-72-7) has anti-inflammatory properties, which can help reduce redness and irritation associated with various skin conditions, including acne.
As a keratolytic agent, Salicylic Acid (Cas 69-72-7) helps to soften and loosen the outer layer of the skin.

This makes it easier to remove dead skin cells and encourages the growth of new, healthier skin.
Salicylic Acid (Cas 69-72-7) is also used in some over-the-counter products designed for the removal of common warts and plantar warts.
The acid works by breaking down the protein in the skin cells of the wart.

When incorporating Salicylic Acid (Cas 69-72-7) into a skincare routine, it's recommended to start with a lower concentration and gradually increase if needed.
Salicylic Acid (Cas 69-72-7) is often used in leave-on products like toners, serums, and spot treatments.
Sunscreen should be applied during the day when using products containing Salicylic Acid (Cas 69-72-7), as it can increase sensitivity to sunlight.

Salicylic Acid (Cas 69-72-7) is sometimes combined with other active ingredients, such as benzoyl peroxide or alpha hydroxy acids (AHAs), to enhance its effectiveness in treating acne and improving skin texture.
As such, Salicylic Acid (Cas 69-72-7) is used to treat warts, psoriasis, acne vulgaris, ringworm, dandruff, and ichthyosis.
Isoamyl salicylate has orchid aroma, benzyl salicylate has weak ester aroma, both can prepare perfume or soap flavor.

The common name of phenyl salicylate is Salo, was hydrolyzed into phenol and Salicylic Acid (Cas 69-72-7) in the intestine, is a kind of effective enteral preservatives.
In addition to being an important active metabolite of aspirin (acetylsalicylic acid), which acts in part as a prod rug to Salicylic Acid (Cas 69-72-7), it is probably best known for its use in anti-acne treatments.
The salts and esters of Salicylic Acid (Cas 69-72-7) are known as salicylates.

Salicylic Acid (Cas 69-72-7) has the formula C6H4(OH) COOH, where the OH group is ortho to the carboxyl group.
The name is from Latin salix for willow tree, from which it was initially identified and derived.
Salts and esters of Salicylic Acid (Cas 69-72-7) are known as salicylates.

In dye industry, Salicylic Acid (Cas 69-72-7) is used for production mordant pure yellow, direct yellow 3GN, direct yellow GR, direct brown 3GN, acid mordant brown G, acid mordant yellow GG, acid yellow dye complex.
In pesticide production, Salicylic Acid (Cas 69-72-7) is used for the synthesis of organic phosphorus pesticide Isocarbophos, intermediate isopropyl salicylate isofenphos methyl and Rodenticide warfarin, coumatetralyl intermediate 4-hydroxycoumarin.

In rubber industry, Salicylic Acid (Cas 69-72-7) is used as anti scorching agent and production of ultraviolet absorbent and foaming agent.
Salicylic Acid (Cas 69-72-7) a colorless, bitter-tasting solid, it is a precursor to and a metabolite of aspirin (acetylsalicylic acid).
Salicylic Acid (Cas 69-72-7), also known as 2-carboxyphenol or 2-hydroxybenzoate, belongs to the class of organic compounds known as salicylic acids.

In the pharmaceutical industry, the main drug productions of Salicylic Acid (Cas 69-72-7) are sodium salicylate, wintergreen oil (methyl salicylate), aspirin (acetylsalicylic acid), salicylic acid amine, phenyl salicylate.
These are ortho-hydroxylated benzoic acids.
Salicylic Acid (Cas 69-72-7) exists in all living species, ranging from bacteria to plants to humans.

Based on a literature review a significant number of articles have been published on Salicylic Acid (Cas 69-72-7).
Salicylic Acid (Cas 69-72-7), is a monohydroxybenzoic acid.
Salicylic Acid (Cas 69-72-7) is a type of beta hydroxy acid (BHA) and is derived from the bark of the willow tree.

Salicylic Acid (Cas 69-72-7) has both anti-inflammatory and exfoliating properties, making it a common ingredient in skincare products.
Salicylic Acid (Cas 69-72-7) is an ingredient in some anti-acne products.
Salicylic Acid (Cas 69-72-7) is an important organic synthetic raw material, widely used in medicine, pesticides, dyes, rubber, food and perfumes.

Melting point: 158-161 °C(lit.)
Boiling point: 211 °C(lit.)
Density: 1.44
vapor density: 4.8 (vs air)
vapor pressure: 1 mm Hg ( 114 °C)
refractive index: 1,565
FEMA: 3985 | 2-HYDROXYBENZOIC ACID
Flash point: 157 °C
storage temp.: 2-8°C
solubility: ethanol: 1 M at 20 °C, clear, colorless
pka: 2.98(at 25℃)
form: Solid
color: White to off-white
PH Range: Non0 uorescence (2.5) to dark blue 0 uorescence (4.0)
Odor: at 100.00 %. faint phenolic nutty
PH: 3.21(1 mM solution);2.57(10 mM solution);2.02(100 mM solution);
Odor Type: nutty
Water Solubility: 1.8 g/L (20 ºC)
Sensitive: Light Sensitive
λmax: 210nm, 234nm, 303nm
Merck: 14,8332
JECFA Number: 958
Sublimation: 70 ºC
LogP: 2.01

Salicylic Acid (Cas 69-72-7), especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat.
Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat.
Salicylic Acid (Cas 69-72-7) is biosynthesized from the amino acid phenylalanine.

In Arabidopsis thaliana Salicylic Acid (Cas 69-72-7) can also be synthesized via a phenylalanine - independent pathway.
Sodium salicylate is commercially prepared by treating sodium phenolate (the sodium salt of phenol) with carbon dioxide at high pressure (100 atm) and high temperature (390K) -a method known as the Kolbe-Schmitt reaction.
Acidification of the product with sulfuric acid gives Salicylic Acid (Cas 69-72-7).

Salicylic Acid (Cas 69-72-7) can also be prepared by the hydrolysis of aspirin (acetylsalicylic acid) or methyl salicylate (oil of winter green) with a strong acid or base.
Salicylic Acid (Cas 69-72-7) is a carboxylic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them.
They react in this way with all bases, both organic (for example, the amines) and inorganic.

Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat.
Neutralization between an acid and a base produces water plus a salt.
Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water.

When it Salicylic Acid (Cas 69-72-7) combined with sulfur, some believe that a synergistic keratolytic effect is produced.
Common preparations include a 3% and 6% ointment with equal concentration of sulfur; 6% propylene glycol solution (Keralyt); 5% to 20% with equal parts of lactic acid in flexible collodion for warts (Duofilm, Occlusal); in a cream base at any concentration for keratolytic effects; as a 60% ointment for plantar warts; and in a 40% plaster on velvet cloth for the treatment of calluses and warts (40% Salicylic Acid (Cas 69-72-7) plaster).

A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position.
Salicylic Acid (Cas 69-72-7) has been shown to work through several different pathways.
Salicylic Acid (Cas 69-72-7) produces its anti - inflammatory effects via suppressing the activity of cyclo oxygenase (COX), an enzyme which is responsible for the production of pro - inflammatory mediators such as the prostaglandins.

Salicylic Acid (Cas 69-72-7) does this not by direct inhibition of COX, unlike most other non-steroidal anti-inflammatory drugs (NSAIDs), but instead by suppression of the expression of the enzyme (via a yet-un elucidated mechanism).
Salicylic Acid (Cas 69-72-7) has also been shown to activate adenosine monophosphate-activated protein kinase (AMPK), and it is thought that this action may play a role in the anticancer effects of the compound and its prod rugs aspirin and salsalate.
In addition, the anti diabetic effects of Salicylic Acid (Cas 69-72-7) are likely mediated by AMPK activation primarily through allosteric conformational change that increases levels of phosphorylation.

Salicylic Acid (Cas 69-72-7) also uncouples oxidative phosphorylation which leads to increased ADP:ATP and AMP:ATP ratios in the cell.
Consequently, Salicylic Acid (Cas 69-72-7) may alter AMPK activity and subsequently exert its anti-diabetic properties through altered energy status of the cell.
The clinical application of aspirin varies with the therapeutic dose.

Salicylic Acid (Cas 69-72-7) occurs in plants as free Salicylic Acid (Cas 69-72-7) and its carboxylated esters and phenolic glycosides.
Several studies suggest that humans metabolize Salicylic Acid (Cas 69-72-7) in measurable quantities from these plants.
High-Salicylic Acid (Cas 69-72-7) beverages and foods include beer, coffee, tea, numerous fruits and vegetables, sweet potato, nuts, and olive oil.

Meat, poultry, fish, eggs, dairy products, sugar, breads and cereals have low salicylate content.
Some people with sensitivity to dietary Salicylic Acid (Cas 69-72-7) may have symptoms of allergic reaction, such as bronchial asthma, rhinitis, gastrointestinal disorders, or diarrhea, so may need to adopt a low-salicylate diet.
A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically.

Salicylic Acid (Cas 69-72-7) has bacteriostatic, fungicidal, and keratolytic actions.
Salicylic Acid (Cas 69-72-7) is salts, the salicylates, are used as analgesics.
Salicylic Acid (Cas 69-72-7) is used in the production of other pharmaceuticals, including 4-aminosalicylic acid, sandulpiride, and landetimide (via salethamide).

Salicylic Acid (Cas 69-72-7) has long been a key starting material for making acetyl2-Hydroxybenzoic acid (salicylic acid) (aspirin).
Salicylic Acid (Cas 69-72-7) is prepared by the esterification of the phenolic hydroxyl group of Salicylic Acid (Cas 69-72-7) with the acetyl group from acetic anhydride or acetyl chloride.
Low-dose aspirin (75–300?mg/day) has antiplatelet aggregation effect and can be used to prevent and treat the coronary and cerebrovascular thrombosis and other postoperative thrombosis.

The middle dose of aspirin (0.5–3? g/day) has antipyretic analgesic effects, so it is commonly used in the treatment of fever, headache, toothache, neuralgia, muscle pain and menstrual pain.
Salicylic Acid (Cas 69-72-7) lowers skin pH, increases corneocyte hydration and dissolves the intercellular binder between corneocytes.
Salicylic Acid (Cas 69-72-7) and sulfur are thought to be synergistic in their keratolytic actions.

Salicylic Acid (Cas 69-72-7) is a phenolic phytohormone and is found in plants with roles in plant growth and development, photosynthesis, transpiration, ion uptake and transport.
Salicylic Acid (Cas 69-72-7) also induces specific changes in leaf anatomy and chloroplast structure.
Salicylic Acid (Cas 69-72-7) is involved in endogenous signaling, mediating in plant defense against pathogens.

Salicylic Acid (Cas 69-72-7) plays a role in the resistance to pathogens by inducing the production of pathogenesis-related proteins.
Salicylic Acid (Cas 69-72-7) is involved in the systemic acquired resistance (SAR) in which a pathogenic attack on one part of the plant induces resistance in other parts.
The signal can also move to nearby plants by Salicylic Acid (Cas 69-72-7) being converted to the volatile ester, methyl salicylate.

Salicylic Acid (Cas 69-72-7) modulates COX-1 enzymatic activity to decrease the formation of pro-inflammatory prostaglandins.
Salicylic Acid (Cas 69-72-7) may competitively inhibit prostaglandin formation.
Salicylic Acid (Cas 69-72-7)'s antirheumatic (nonsteroidal anti-inflammatory) actions are a result of its analgesic and anti-inflammatory mechanisms.[citation needed]

Salicylic Acid (Cas 69-72-7), when applied to the skin surface, works by causing the cells of the epidermis to slough off more readily, preventing pores from clogging up, and allowing room for new cell growth.
Salicylic Acid (Cas 69-72-7) is the standard to which all the other non-steroidal anti-inflammatory drugs (NSAIDs) are compared.
In veterinary medicine, this group of drugs is mainly used for the treatment of inflammatory musculoskeletal disorders.

Bismuth subsalicylate, a salt of bismuth and Salicylic Acid (Cas 69-72-7), is the active ingredient in stomach-relief aids such as Pepto-Bismol, is the main ingredient of Kaopectate, and "displays anti inflammatory action (due to Salicylic Acid (Cas 69-72-7)) and also acts as an antacid and mild antibiotic.
Salicylic Acid (Cas 69-72-7) is often included in skincare formulations alongside other beneficial ingredients.
For example, Salicylic Acid (Cas 69-72-7) may be added to provide hydration, and niacinamide may offer additional anti-inflammatory and skin-brightening benefits.

The use of Salicylic Acid (Cas 69-72-7) for medicinal purposes dates back centuries.
Willow bark, which contains Salicylic Acid (Cas 69-72-7), has been used for its pain-relieving properties since ancient times.
The isolation and synthesis of Salicylic Acid (Cas 69-72-7) in its pure form began in the 19th century.

The effectiveness of Salicylic Acid (Cas 69-72-7) can be influenced by the pH of the formulation.
Salicylic Acid (Cas 69-72-7) is most effective at a lower pH, typically around 3 to 4.
Skincare products containing Salicylic Acid (Cas 69-72-7) are often formulated within this pH range to maximize their exfoliating and acne-fighting properties.

Salicylic Acid (Cas 69-72-7) inhibits the oxidation of uridine-5-diphosphoglucose (UDPG) competitively with NADH and noncompetitively with UDPG.
Salicylic Acid (Cas 69-72-7) also competitively inhibits the transferring of glucuronyl group of uridine-5-phosphoglucuronic acid to the phenolic acceptor.
High doses of aspirin (more than 4g/day) have anti-inflammatory and antirheumatic effects for the treatment of acute rheumatic fever and rheumatoid arthritis.

In addition, aspirin is used for the treatment of skin and mucous membrane lymphadenopathy (Kawasaki disease) in paediatric.
Salicylic Acid (Cas 69-72-7) are available in many over-the-counter skincare products, higher concentrations may be used in prescription-strength treatments prescribed by dermatologists for more severe acne or certain skin conditions.
Salicylic Acid (Cas 69-72-7) is not only used to treat active acne but can also be incorporated into a skincare routine for maintenance and preventive purposes.

Regular use can help manage oiliness, prevent clogged pores, and maintain clearer skin.
Individuals with certain skin conditions, such as rosacea, eczema, or extremely sensitive skin, may find Salicylic Acid (Cas 69-72-7) too harsh.
Salicylic Acid (Cas 69-72-7)'s essential to choose skincare ingredients based on individual skin types and concerns.

Continuous, long-term use of salicylic acid is generally safe for many people, but it's advisable to give the skin periodic breaks from exfoliating products.
Salicylic Acid (Cas 69-72-7) is keratolytic and at concentrations between 3% and 6% causes softening of the horny layers and shedding of scales.
Salicylic Acid (Cas 69-72-7) may be obtained (1) from oil of wintergreen, which contains methyl salicylate, or by heating dry sodium phenate C6H5ONa plus carbon dioxide under pressure at 130 °C (266°F) and recovering from the resulting sodium salicylate by adding dilute sulfuric acid.

Salicylic Acid (Cas 69-72-7) is a β-hydroxy acid that penetrates into the sebaceous gland and has comedolytic and anti-inflammatory properties.
Salicylic Acid (Cas 69-72-7) can be used as an adjunctive therapy and is found in cleansers, toners, masks, and peels.
Salicylic Acid (Cas 69-72-7) produces this desquamation by solubilizing the intercellular cement and enhances the shedding of corneocytes by decreasing cell-to-cell cohesion.

In concentrations >6%, Salicylic Acid (Cas 69-72-7) can be destructive to tissue.
Application of large amounts of the higher concentration of Salicylic Acid (Cas 69-72-7) can also result in systemic toxicity.
Salicylic Acid (Cas 69-72-7) is used in the treatment of superficial fungal infections, acne, psoriasis, seborrheic dermatitis, warts, and other scaling dermatoses.

Salicylic Acid (Cas 69-72-7) is obtained from the bark of the white willow and wintergreen leaves.
Salicylic Acid (Cas 69-72-7) is probably known for its use as an important ingredient in topical anti-acne products.
The salts and esters of Salicylic Acid (Cas 69-72-7) are salicylates.

Salicylic Acid (Cas 69-72-7) is on the World Health Organization’s List of Essential Medicines.
Salicylic Acid (Cas 69-72-7) is the safest and most effective medicines needed in a health system.

Salicylic Acid (Cas 69-72-7) to corrode or dissolve iron, steel, and aluminum parts and containers.
Salicylic Acid (Cas 69-72-7), like other acids, react with cyanide salts to generate gaseous hydrogen cyanide.

History Of Salicylic Acid (Cas 69-72-7):
Willow has long been used for medicinal purposes.
Dioscorides, whose writings were highly influential for more than 1,500 years, used 'Itea' (which was possibly a species of willow) as a treatment for 'painful intestinal obstructions,' birth control, for 'those
who spit blood,' to remove calluses and corns and, externally, as a 'warm pack for gout.'

William Turner, in 1597, repeated this, saying that willow bark, 'being burnt to ashes, and steeped in vinegar, takes away corns and other like risings in the feet and toes.
Some of these cures may describe the action of Salicylic Acid (Cas 69-72-7), which can be derived from the salicin present in willow.
Salicylic Acid (Cas 69-72-7) is, however, a modern myth that Hippocrates used willow as a painkiller.

Hippocrates, Galen, Pliny the Elder, and others knew that decoctions containing salicylate could ease pain and reduce fevers.
Salicylic Acid (Cas 69-72-7) was used in Europe and China to treat these conditions.
This remedy is mentioned in texts from Ancient Egypt, Sumer, and Assyria.

The Cherokee and other Native Americans use an infusion of the bark for fever and other medicinal purposes.
In 2014, archaeologists identified traces of Salicylic Acid (Cas 69-72-7) on seventh-century pottery fragments found in east-central Colorado.
The Reverend Edward Stone, a vicar from Chipping Norton, Oxfordshire, England, reported in 1763 that the bark of the willow was effective in reducing a fever.

An extract of willow bark, called Salicylic Acid (Cas 69-72-7), after the Latin name for the white willow (Salix alba), was isolated and named by German chemist Johann Andreas Buchner in 1828.
A larger amount of the substance was isolated in 1829 by Henri Leroux, a French pharmacist.
Raffaele Piria, an Italian chemist, was able to convert the substance into a sugar and a second component, which on oxidation becomes Salicylic Acid (Cas 69-72-7).

Salicylic Acid (Cas 69-72-7) was also isolated from the herb meadowsweet (Filipendula ulmaria, formerly classified as Spiraea ulmaria) by German researchers in 1839.
Their extract caused digestive problems such as gastric irritation, bleeding, diarrhea, and even death when consumed in high doses.
In 1874 the Scottish physician Thomas MacLagan experimented with Salicylic Acid (Cas 69-72-7) as a treatment for acute rheumatism, with considerable success, as he reported in The Lancet in 1876.

Meanwhile, German scientists tried sodium salicylate with less success and more severe side effects.
In 1979, salicylates were found to be involved in induced defenses of tobacco against tobacco mosaic virus.
In 1987, salicylic acid was identified as the long-sought signal that causes thermogenic plants, such as the voodoo lily, Sauromatum guttatum, to produce heat.

Methods of production Of Salicylic Acid (Cas 69-72-7):
The phenol and sodium hydroxide react to produce phenol sodium, distillation and dehydration, CO2 carboxylation reaction to obtain sodium salicylate, then using sulfuric acid and produce crude product.
The crude product through the sublimation refined to the finished product.
Raw materials consumption quota: phenol (98%) 704kg/t, alkali burn (95%) 417kg/t, sulfate (95%) 500kg/t, carbon dioxide (99%) 467kg/t.

The preparation method of the method is that the sodium salt of phenol and carbon dioxide can be obtained by acidification.
Phenol and liquid caustic soda are produced into solution of the sodium salt of phenol, vacuum drying, and then to 100℃, slowly put to the dry carbon dioxide, when the pressure reaches 0.7~0.8MPa, stop passing carbon dioxide, warming up to 140 to 180℃.
After the reaction with water, sodium salicylate dissolved and decolorization, filtering, coupled with the sulfuric acid, namely precipitation Salicylic Acid (Cas 69-72-7), after filtering, washing and drying to obtain the product.

Uses:
Salicylic Acid (Cas 69-72-7) is used in over-the-counter treatments for the removal of corns and calluses.
Salicylic Acid (Cas 69-72-7) helps break down the thickened skin.
Salicylic Acid (Cas 69-72-7) is included in some foot creams and treatments to soften calluses and rough skin on the feet.

Salicylic Acid (Cas 69-72-7) is found in some plants, particularly the leaves of wintergreen, willow bark, and the bark of sweet birch.
Salicylic Acid (Cas 69-72-7) is also synthetically manufactured.
Salicylic Acid (Cas 69-72-7) can be beneficial in addressing post-inflammatory hyperpigmentation (dark spots) left behind by acne lesions.

Salicylic Acid (Cas 69-72-7) is exfoliating properties help in promoting skin renewal and fading discoloration over time.
Salicylic Acid (Cas 69-72-7) is an FDA approved skin care ingredient used for the topical treatment of acne, and it's the only beta hydroxy acid (BHA) used in skin care products.
Salicylic Acid (Cas 69-72-7) is a common ingredient in various cosmetic formulations, including cleansers, toners, serums, and spot treatments.

Salicylic Acid (Cas 69-72-7) is versatility makes it suitable for a range of skincare products.
When using products containing Salicylic Acid (Cas 69-72-7), it's crucial to use sunscreen during the day.
Salicylic Acid (Cas 69-72-7) can increase sensitivity to sunlight, and regular sun protection helps prevent further skin damage.

Many over-the-counter products, such as face washes, pads, and spot treatments, contain Salicylic Acid (Cas 69-72-7).
These products are readily available for consumers to use in their daily skincare routines.
Salicylic Acid (Cas 69-72-7) is known for its ability to ease aches and pains and reduce fevers.

These medicinal properties, particularly fever relief, have been known since ancient times, and it is used as an antiinflammatory drug.
In modern medicine, Salicylic Acid (Cas 69-72-7) and its derivatives are used as constituents of some rubefacient products.
For example, Salicylic Acid (Cas 69-72-7) is used as a liniment to soothe joint and muscle pain, and choline salicylate is used topically to relieve the pain of mouth ulcers.

Salicylic Acid (Cas 69-72-7) also exfoliates dead skin, and its anti-inflammatory properties make it a prime ingredient for those with psoriasis.
Salicylic Acid (Cas 69-72-7) naturally occurs in willow bark, sweet birch bark, and wintergreen leaves, but synthetic versions are also used in skin care products.
Although toxic in large quantities, Salicylic Acid (Cas 69-72-7) is used as a food preservative and as bactericidal and an antiseptic.

For some people with Salicylic Acid (Cas 69-72-7) sensitivity even these small doses can be harmful.
Salicylic Acid (Cas 69-72-7) is a useful phosphor in the vacuum ultraviolet with nearly flat quantum efficiency for wavelengths between 10 to 100 nm.
Salicylic Acid (Cas 69-72-7) fluoresces in the blue at 420 nm.

Salicylic Acid (Cas 69-72-7) is easily prepared on a clean surface by spraying a saturated solution of the salt in methanol followed by evaporation.
Salicylic Acid (Cas 69-72-7) is widely used, eczema, psoriasis, salicylic acid can be used in acne, dandruff.
Salicylic Acid (Cas 69-72-7) is used as a food preservative, a bactericide, and an antiseptic.

Salicylic Acid (Cas 69-72-7) is used in the production of other pharmaceuticals, including 4-aminosalicylic acid, sandulpiride, and landetimide (via salethamide).
Salicylic Acid (Cas 69-72-7) has long been a key starting material for making acetylsalicylic acid (aspirin).
Salicylic Acid (Cas 69-72-7) is prepared by the esterification of the phenolic hydroxyl group of salicylic acid with the acetyl group from acetic anhydride or acetyl chloride.

Salicylic Acid (Cas 69-72-7) is the standard to which all the other non-steroidal anti-inflammatory drugs (NSAIDs) are compared.
In veterinary medicine, this group of drugs is mainly used for treatment of inflammatory musculoskeletal disorders.
Bismuth subsalicylate, a salt of bismuth and Salicylic Acid (Cas 69-72-7), "displays anti-inflammatory action (due to salicylic acid) and also acts as an antacid and mild antibiotic".

Salicylic Acid (Cas 69-72-7) is the active ingredient in stomach-relief aids such as Pepto-Bismol and some formulations of Kaopectate.
Other derivatives include methyl Salicylic Acid (Cas 69-72-7) used as a liniment to soothe joint and muscle pain and choline salicylate used topically to relieve the pain of mouth ulcers.
Salicylic Acid (Cas 69-72-7) is used to induce remission in ulcerative colitis, and has been used as an antitubercular agent often administered in association with isoniazid.

Salicylic Acid (Cas 69-72-7) is a useful phosphor in the vacuum ultraviolet spectral range, with nearly flat quantum efficiency for wavelengths between 10 and 100 nm.
Salicylic Acid (Cas 69-72-7) fluoresces in the blue at 420 nm.
Salicylic Acid (Cas 69-72-7) is easily prepared on a clean surface by spraying a saturated solution of the salt in methanol followed by evaporation

Other derivatives include Salicylic Acid (Cas 69-72-7) used as a liniment to soothe joint and muscle pain and choline salicylate used topically to relieve the pain of mouth ulcers.
Salicylic Acid (Cas 69-72-7) is used to induce remission in ulcerative colitis and has been used as an antitubercular agent often administered in association with isoniazid.
Salicylic Acid (Cas 69-72-7) is a useful phosphor in the vacuum ultraviolet spectral range, with nearly flat quantum efficiency for wavelengths between 10 and 100 nm.

Salicylic Acid (Cas 69-72-7) fluoresces in the blue at 420 nm.
Salicylic Acid (Cas 69-72-7) is easily prepared on a clean surface by spraying a saturated solution of the salt in methanol followed by evaporation.
Salicylic Acid (Cas 69-72-7) is widely used to treat acne.

Salicylic Acid (Cas 69-72-7) penetrates the pores and helps to exfoliate dead skin cells, unclog pores, and reduce inflammation.
The concentration of 3%~6% can be used to horny, higher than 6% of salicylic acid can damage to tissue.
Below 40% of concentration is suitable for the treatment of thick cocoon, corns and warts.

Salicylic Acid (Cas 69-72-7) can also be added in the treatment of acne and dandruff.
Nowadays many famous cosmetic ingredients: in 1993, Clinique CLINIQUE first launched 1% Salicylic Acid (Cas 69-72-7) in soft water cream, immediately became one of Clinique's most successful products; In 1998, SK-II crystal induced skin cream added 1.5%BHA ingredients to the original, and salicylic acid has effect of treatment pores and cutin like the egg peeling analogy that caused the market boom; open access Olay popular products activating cream also contains 1.5% BHA components.
However, due to the high concentration of Salicylic Acid (Cas 69-72-7), it has a certain degree of damage, cosmetics containing salicylic acid concentration has generally been limited between 0.2%~1.5%, containing

Salicylic Acid (Cas 69-72-7) cosmetics shall be added to the note of warning signs to determine the safety of long-term use and children under 3 years of age also shall not be used.
Salicylic Acid (Cas 69-72-7) is a beta-hydroxy acid with keratolytic and antiinflammatory activity.
Because Salicylic Acid (Cas 69-72-7) is lipid soluble, it can more easily reduce sebaceous follicle blockage by penetrating the pores and exfoliating the cellular buildup.
Salicylic Acid (Cas 69-72-7) is antimicrobial, anti-septic, enhances the activity of preservatives, and can be used to adjust the pH of products.

For the treatment of aging skin, Salicylic Acid (Cas 69-72-7) appears to help improve skin wrinkles, roughness, and tone.
Salicylic Acid (Cas 69-72-7) helps dissolve the top layer of stratum corneum cells, improving the look and feel of the skin.
Salicylic Acid (Cas 69-72-7) is an effective ingredient in acne products and as such is widely used in acne soaps and lotions.

Perfect for oily skin, Salicylic Acid (Cas 69-72-7) is best known for its ability to deep clean excess oil out of pores and reduce oil production moving forward. Because salicylic acid keeps pores clean and unclogged, it prevents future whiteheads and blackheads from developing.
Salicylic Acid (Cas 69-72-7) helps to keep hair follicles clear and reduce inflammation.
Salicylic Acid (Cas 69-72-7) may be included in formulations to address certain skin conditions, such as seborrheic dermatitis or psoriasis.

Salicylic Acid (Cas 69-72-7) is used for its analgesic (pain-relieving), anti-inflammatory, and antipyretic (fever-reducing) properties.
Salicylic Acid (Cas 69-72-7) can help manage scaling and flaking associated with these conditions.
In higher concentrations, Salicylic Acid (Cas 69-72-7) is used in professional chemical peels.

It is used at high concentrations, Salicylic Acid (Cas 69-72-7) may cause skin redness and rashes.
This is a naturally occurring organic acid, related to aspirin.
Salicylic Acid (Cas 69-72-7) is effective in managing excess oil production on the skin.

By unclogging pores and reducing sebum, Salicylic Acid (Cas 69-72-7) can contribute to a more balanced complexion.
Regular use of Salicylic Acid (Cas 69-72-7) can be a preventive measure against acne breakouts.
Salicylic Acid (Cas 69-72-7) helps maintain clear pores and prevents the accumulation of dead skin cells that can lead to blemishes.

Salicylic Acid (Cas 69-72-7) is often used in combination with other active ingredients, such as benzoyl peroxide or retinoids, for a more comprehensive approach to acne treatment.
Salicylic Acid (Cas 69-72-7)'s exfoliating properties make it useful in preventing and treating ingrown hairs.
Salicylic Acid (Cas 69-72-7) is effective for both non-inflammatory acne (blackheads and whiteheads) and inflammatory acne (pimples and cysts).

Salicylic Acid (Cas 69-72-7)'s exfoliating properties make it useful for improving skin texture, promoting cell turnover, and addressing issues like rough or uneven skin.
Salicylic Acid (Cas 69-72-7) is used in some over-the-counter products designed for the removal of common warts and plantar warts.
Salicylic Acid (Cas 69-72-7) works by breaking down the structure of the wart.

Salicylic Acid (Cas 69-72-7) is a precursor to acetylsalicylic acid, commonly known as aspirin.
Salicylic Acid (Cas 69-72-7) has mild anti-inflammatory effects, and this property is utilized in skincare for reducing redness and irritation.
Dermatologists may prescribe higher concentrations of Salicylic Acid (Cas 69-72-7) for specific skin conditions, such as more severe acne or certain types of dermatitis.

Safety Profile:
Salicylic Acid (Cas 69-72-7) is used in the manufacture of aspirin.
Salicylic Acid (Cas 69-72-7)'s advisable to perform a patch test before widespread use, especially for those with sensitive skin.

Salicylic Acid (Cas 69-72-7) can increase skin sensitivity to sunlight.
It's essential to use sunscreen during the day when using products containing Salicylic Acid (Cas 69-72-7) to prevent sunburn and further skin damage.
Allergic reactions can include itching, swelling, or rash.

If such reactions occur, discontinue use and seek medical advice.
Despite the potential teratogenic risk of Salicylic Acid (Cas 69-72-7), cosmetic applications of the drug pose no significant risk.
When heated to decomposition it emits acrid smoke and irritating fumes.

If high concentrations of Salicylic Acid (Cas 69-72-7) ointment are used topically, high levels of salicylic acid can enter the blood, requiring hemodialysis to avoid further complications.
Some individuals may be more sensitive to salicylic acid, experiencing redness, irritation, or dryness.

Overusing products containing Salicylic Acid (Cas 69-72-7) or using higher concentrations than recommended can lead to excessive dryness and peeling.
Following product instructions and incorporating Salicylic Acid (Cas 69-72-7) gradually into a skincare routine is crucial.

SALICYLIC ACID (SA)
Salicylic acid (SA) is an organic compound with the formula HOC6H4COOH.
Salicylic acid (SA) has bacteriostatic, fungicidal, and keratolytic actions.
Salicylic acid (SA) is odourless and is colourless.


CAS-Number: 69-72-7
EC Number: 200-712-3
MDL number: MFCD00002439
Chemical Name: 2 – Hydroxybenzoic Acid
Linear Formula: 2-(HO)C6H4CO2H
Molecular Formula: C7H6O3



2-Hydroxybenzoic acid, 2-HYDROXYBENZOIC ACID, ACIDUM SALICYLICUM, ACETYLSALISYLIC ACID IMP C, ACETYLSALICYLIC ACID IMPURITY C, FEMA 3985, SALICYCLIC ACID, SALICYLIC ACID, RETARDER TSA, salicylic acid, 2-Hydroxybenzoic acid, 69-72-7, o-hydroxybenzoic acid, 2-Carboxyphenol, o-Carboxyphenol, Rutranex, Salonil, Retarder W, Duoplant, Keralyt, Psoriacid-S-stift, Freezone, Saligel, Ionil, Salicylic acid soap, Stri-Dex, Verrugon, Salicylic acid collodion,
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Salicylic acid (SA) is a compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically.
Salicylic acid (SA) has bacteriostatic, fungicidal, and keratolytic actions.
Salicylic acid (SA) is a metabolite found in or produced by Escherichia coli


Salicylic acid (SA) is a beta hydroxy acid that occurs as a natural compound in plants.
Salicylic acid (SA) has direct activity as an anti-inflammatory agent and acts as a topical antibacterial agent due to its ability to promote exfoliation.
Salicylic acid (SA) is a compound obtained from the bark of the white willow and wintergreen leaves.


Salicylic acid (SA) has bacteriostatic, fungicidal, and keratolytic actions.
A colorless, bitter-tasting solid, Salicylic acid (SA) is a precursor to and a metabolite of aspirin (acetylsalicylic acid).
Salicylic acid (SA) is a plant hormone, and has been listed by the EPA Toxic Substances Control Act (TSCA) Chemical Substance Inventory as an experimental teratogen.


The name is from Latin salix for willow tree, from which Salicylic acid (SA) was initially identified and derived.
Salicylic acid (SA) is an ingredient in some anti-acne products.
Salts and esters of Salicylic acid (SA) are known as salicylates.


Salicylic acid (SA) is an odorless white to light tan solid.
Salicylic acid (SA) sinks and mixes slowly with water.
Salicylic acid (SA) is a useful phosphor in the vacuum ultraviolet spectral range, with nearly flat quantum efficiency for wavelengths between 10 and 100 nm.


Salicylic acid (SA) fluoresces in the blue at 420 nm.
Salicylic acid (SA) is easily prepared on a clean surface by spraying a saturated solution of the salt in methanol followed by evaporation.
Salicylic acid (SA) a monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position.


Salicylic acid (SA) is obtained from the bark of the white willow and wintergreen leaves.
Salicylic acid (SA) has a role as an antiinfective agent, an antifungal agent, a keratolytic drug, an EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor, a plant metabolite, an algal metabolite and a plant hormone.


Salicylic acid (SA) is a conjugate acid of a salicylate.
Salicylic acid (SA) is lipophilic monohydroxybenzoic acid.
Salicylic acid (SA) a type of phenolic acid and a beta-hydroxy acid (BHA).


Beta hydroxy acid is found as a natural compound in plants.
This colourless crystalline organic acid, Salicylic acid (SA), is broadly in use in organic synthesis.
Salicylic acid (SA) is derived from the metabolism of salicin.


Salicylic acid (SA) is a crystalline organic carboxylic acid and has keratolytic, bacteriostatic and fungicidal properties.
Salicylic acid (SA) can be in use as an antiseptic and as a food preservative when consumed in small quantities.
Salicylic acid (SA) has a carboxyl group attached to it i.e., COOH.


Salicylic acid (SA) is odourless and is colourless.
Salicylic acid (SA) is probably known for its use as an important ingredient in topical anti-acne products.
The salts and esters of Salicylic acid (SA) are salicylates.


Salicylic acid (SA) is on the World Health Organization’s List of Essential Medicines.
Salicylic acid (SA) is the safest and most effective medicines needed in a health system.
Salicylic acid (SA), also known as 2-Hydroxybenzoic Acid, 2-Carboxyphenol, and o-Hydroxybenzoic Acid has the chemical formula C7H6O3.


Salicylic acid (SA) appears as an odorless, white-colored to light tan solid with an acrid taste.
Salicylic acid (SA) is slightly soluble in Water, therefore, when added to Water, it sinks and slowly mixes with it at ambient conditions.
Salicylic acid (SA) is in use in the treatment of wart infections.


The mechanism of Salicylic acid (SA) by which professionals treats warts infection is similar to its keratolytic action.
Firstly, Salicylic acid (SA) dehydrates the skin cells that are affected by warts and thereby it gradually leads to its shedding off from the body.
Salicylic acid (SA) also activates the immune reaction of the body towards the viral wart infection by initiating a mild inflammatory reaction.


Salicylic acid (SA) is one of the major components of anti-dandruff shampoos.
Salicylic acid (SA) also helps in clearing away the dead and flaky skin cells from your scalp.
Salicylic acid (SA) is a monohydroxybenzoic acid, benzoic acid with a hydroxy group in the ortho position.


Salicylic acid (SA) is obtained from the bark of white willow and wintergreen leaves.
Salicylic acid (SA) has a role as antiinfective agent, antifungal agent, keratolytic drug, EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor, plant metabolite, algal metabolite and plant hormone.


Salicylic acid (SA) is the conjugate acid of a salicylate.
Salicylic acid (SA), also known as o-hydroxybenzoic acid, is a component with a structure similar to β-hydroxy acid, which can not only soften the stratum corneum, but also loosen the horn plugs to unclog pores, as well as certain antibacterial and anti-inflammatory effects.


Salicylic acid (SA) is not easily soluble in water, but is easily soluble in organic solvents such as ethanol, ether, propanol, and turpentine.
Salicylic acid (SA) exists in willow bark, white pearl leaves, and sweet birch in nature, and is the "anti-inflammatory drug" of plants.
Humans have long discovered the medicinal properties of willow plant extracts (natural Salicylic acid (SA)).


Ancient Sumerian clay tablets have records of using willow leaves to treat arthritis.
The oldest medical text in ancient Egypt, the Ebers Papyrus, records that the pain-relieving properties of dried willow leaves were known to the Egyptians at least more than 2,000 BC.


The ancient Greek physician Hippocrates documented the medicinal properties of willow bark in the 5th century BC.
This knowledge was repeatedly quoted by famous Greek and Roman physicians such as Galen.
Salicylic acid (SA), also known as 2-carboxyphenol or 2-hydroxybenzoate, belongs to the class of organic compounds known as salicylic acids.


These are ortho-hydroxylated benzoic acids.
Salicylic acid (SA) exists in all living species, ranging from bacteria to plants to humans.
Based on a literature review a significant number of articles have been published on Salicylic acid (SA).


Salicylic acid (SA), also called 2-hydrobenzoic or phenolic acid, is a colorless substance in the form of crystals or powder.
Salicylic acid (SA) is one of the most commonly used types of hydroxybenzoic acid.
Phenolic acid is highly soluble in polar solvents of organic origin, such as diethyl ether or ethanol, but slightly soluble in water and carbon disulfide.


The density of Salicylic acid (SA) is 1.44 g/cm³, melting occurs at 159°C, and boils at 211°C.
The production of Salicylic acid (SA) is based on the Kolbe-Schmitt reaction: the carboxylation of sodium phenolate when exposed to carbon dioxide with the creation of the required pressure and temperature for 8-10 hours.


Two grades of the product are produced: A - for the preparation of medicines, B - for other areas of application.
The chemical formula of Salicylic acid (SA) is C7H6O3.
Salicylic acid (SA) is a natural product extract from Willow bark, well known as an antiinflammatory and antinociceptive agent and a close structural relative to acetylsalicylic acid (aspirin).


Salicylic acid (SA) is a ubiquitous plant hormone with many regulatory functions involved in local disease resistance mechanisms and systemic acquired resistance.
The antiinflammatory and antinociceptive effects produced by Salicylic acid (SA) and its derivatives in animals are due to inhibition of COX-1 and COX-2 (cyclooxygenase) enzyme activity and suppression of prostaglandin biosynthesis.


Salicylic acid (SA) is also of interest as a starting material for the organic synthesis of more elaborate COX suppressors and other chemical structures.
Salicylic acid (SA) (from Latin salix, willow tree) is a monohydroxybenzoic acid, a type of phenolic acid and a beta hydroxy acid.
Salicylic acid (SA) has the formula C7H6O3.


In an early (1966) biosynthetic process, researchers at Kerr-McGee Oil Industries (now part of Andarko Petroleum) prepared Salicylic acid (SA) via the microbial degradation of naphthalene.
Salicylic acid (SA) is now commercially biosynthesized from phenylalanine.


Acetylsalicylic acid (aspirin), a prodrug to Salicylic acid (SA), is made by an entirely different process.
Curiously, Salicylic acid (SA) is also a metabolite of aspirin.
Salicylic acid (SA) and its esters are used as food preservatives, in skin-care products and other cosmetics, and in topical medicines.


In 2015, J. L. Dangl, S. L. Lebeis, and co-workers at the University of North Carolina, Chapel Hill, discovered that native Salicylic acid (SA) plays a role in determining which microbes are in the root microbiome of Arabidopsis thaliana, a weed that grows in Europe and Asia.



USES and APPLICATIONS of SALICYLIC ACID (SA):
Uses in manufacturing: Salicylic acid (SA) is used as a food preservative, a bactericide, and an antiseptic.
Salicylic acid (SA) is used in the production of other pharmaceuticals, including 4-aminosalicylic acid, sandulpiride, and landetimide (via salethamide).
Salicylic acid (SA) has long been a key starting material for making acetylsalicylic acid (aspirin).


Aspirin (acetylsalicylic acid or ASA) is prepared by the esterification of the phenolic hydroxyl group of Salicylic acid (SA) with the acetyl group from acetic anhydride or acetyl chloride.
ASA is the standard to which all the other non-steroidal anti-inflammatory drugs (NSAIDs) are compared.


In veterinary medicine, this group of drugs is mainly used for treatment of inflammatory musculoskeletal disorders.
Bismuth subsalicylate, a salt of bismuth and Salicylic acid (SA), "displays anti-inflammatory action (due to salicylic acid) and also acts as an antacid and mild antibiotic".


It is the active ingredient in stomach-relief aids such as Pepto-Bismol and some formulations of Kaopectate.
Other derivatives include methyl salicylate used as a liniment to soothe joint and muscle pain and choline salicylate used topically to relieve the pain of mouth ulcers.


Aminosalicylic acid is used to induce remission in ulcerative colitis, and has been used as an antitubercular agent often administered in association with isoniazid.
Salicylic acid (SA)'s salts, the salicylates, are used as analgesics.


Salicylic acid (SA) is used in the following products: Fertilizers, cosmetics and personal care products, laboratory chemicals and medicines.
Salicylic acid (SA) is used in agriculture, forestry and fisheries, health care and scientific research and development
Salicylic acid (SA) is used in machine wash fluids/detergents, automotive care products, paints, coatings or adhesives, fragrances, air fresheners, coolants in refrigerators and oil-based electric heaters.


Salicylic acid (SA) is particularly in use in the pharmaceutical industry.
The most common use of Salicylic acid (SA) is in the preparation of an analgesic, aspirin, which is an acetylated derivative of Salicylic acid (SA).
Another analgesic formed from it is methyl salicylate, an esterified product of Salicylic acid (SA).


Both of these analgesics are in use to treat headache and other body aches.
Salicylic acid (SA) also in use as a mild antiseptic effect known as a bacteriostatic agent.
Salicylic acid (SA) does not kill the existing bacteria and hence not an antibacterial agent but prevent the growth of bacteria wherever applied.


Common Uses and Applications of Salicylic acid (SA): Treatment for various minor skin conditions, Food preservative, Analytic reagent, Industries,Food & Beverage, Pharmaceutical, and R&D/Laboratory.
Salicylic acid (SA) is a white solid first isolated from the bark of willow trees (Salix spp.), from which it gets its name.


Salicylic acid (SA) is used semiconductors, nanoparticles, photoresists, lubricating oils, UV absorbers, adhesive, leather, cleaner, hair dye, soaps, cosmetics, pain medication, analgesics, antibacterial agent, treatment of dandruff, hyperpigmented skin, tinea pedis, onychomycosis, osteoporosis, beriberi, fungicidal skin disease, autoimmune disease.


In medicine, preparations based on Salicylic acid (SA) are used as an antipyretic, antiseptic, antirheumatic and anti-tuberculosis agent, which has an analgesic and anti-inflammatory effect.
These are aspirin, salicylamide, para-aminosalicylic acid, Lassar paste, preparations for the treatment of corns, ointments, powders.


At food enterprises, Salicylic acid (SA) is used as an antiseptic in the manufacture of canned foods.
Salicylic acid (SA) is added as a component to cosmetics.
Its antibacterial and exfoliating properties make Salicylic acid (SA) possible to soften and remove the keratinized top layer of the skin.


Salicylic acid (SA) is used as a reagent and indicator in chemical reactions.Salicylic acid (SA), GR 99%+ Cas 69-72-7 - used as a reference standard in salicylate quantification by reverse-phase high-performance liquid chromatography (RP-HPLC).
Both oil of wintergreen (methyl 2-hydroxybenzoate) and Salicylic acid (SA) (2-hydroxybenzoic acid) are widely used as pharmaceuticals.


The manufacture of aspirin from Salicylic acid (SA) is of major importance.
Industrially, Salicylic acid (SA) is manufactured at high temperature and pressure from the phenol sodium salt and carbon dioxide, with an annual worldwide production of about 50,000 tonnes.


Salicylic acid (SA) also occurs as the free acid or its esters in many plant species.
Salicylic acid (SA) can be made from methyl 2-hydroxybenzoate which is obtained as oil of wintergreen by distillation from the leaves of Gaultheria procunbers.


-Medicine uses of Salicylic acid (SA):
Salicylic acid (SA) as a medication is commonly used to remove the outer layer of the skin.
As such, Salicylic acid (SA) is used to treat warts, psoriasis, acne vulgaris, ringworm, dandruff, and ichthyosis.
Similar to other hydroxy acids, Salicylic acid (SA) is an ingredient in many skincare products for the treatment of seborrhoeic dermatitis, acne, psoriasis, calluses, corns, keratosis pilaris, acanthosis nigricans, ichthyosis, and warts.



FUNCTIONS OF SALICYLIC ACID (SA):
*Acne treatment, acne treatment - Salicylic acid (SA) is fat-soluble, can penetrate deep into pores to dissolve oil and unclog sebaceous glands; its acidity can dissolve hardened oil and keratin, so that the keratin plugs in the hair follicles can be loosened, and it also has mild anti-inflammatory properties. inflammatory and antibacterial effects.

*Conditioning keratin and improving skin photoaging - Salicylic acid (SA) has a two-way keratin regulating effect and can remove old keratin, so some patients will experience slight scaling, but this is a manifestation of keratin renewal, and it is not suitable for immature keratinization.

On the contrary, the stratum corneum cells have the effect of promoting keratinization and maturation.
Long-term sunlight exposure can cause skin keratin thickening, skin hypertrophy, skin furrows deepen, skin ridges bulge, forming thick and deep wrinkles, so Salicylic acid (SA) can improve skin aging caused by sun exposure.

*Anti-inflammatory and bactericidal - topical application of Salicylic acid (SA) has different degrees of anti-inflammatory, astringent and antipruritic effects on seborrheic dermatitis, papulopustular rosacea, and folliculitis.
The anti-inflammatory effect of aspirin comes from the Salicylic acid (SA) formed after being decomposed in the body; and Salicylic acid (SA) has a certain broad-spectrum bactericidal ability and is effective against many bacteria and fungi.

*Whitening, Eliminate Pigmentation - Salicylic acid (SA) penetrates into pores, dissolves aging keratinocytes, lightens pigmentation and enhances skin cell metabolism.

Salicylic acid (SA) can dissolve the connection between the skin cutin, make the cuticle fall off, remove the excessively thick cuticle, promote epidermal metabolism, rejuvenate and whiten the skin, prevent the generation of acne marks, remove the acne marks that have already occurred, and can prevent UV damage and photoaging.



DIETARY SOURCES OF SALICYLIC ACID (SA):
Salicylic acid (SA) occurs in plants as free Salicylic acid (SA) and its carboxylated esters and phenolic glycosides.
Several studies suggest that humans metabolize Salicylic acid (SA) in measurable quantities from these plants.
High-salicylate beverages and foods include beer, coffee, tea, numerous fruits and vegetables, sweet potato, nuts, and olive oil. Meat, poultry, fish, eggs, dairy products, sugar, breads and cereals have low salicylate content.
Some people with sensitivity to dietary salicylates may have symptoms of allergic reaction, such as bronchial asthma, rhinitis, gastrointestinal disorders, or diarrhea, so may need to adopt a low-salicylate diet.



CHEMICAL PROPERTIES OF SALICYLIC ACID (SA):
*Formation of aspirin:
In the pharmaceutical industry, the most important reaction associated with the use of Salicylic acid (SA) is the production of aspirin i.e., acetylsalicylic acid.

Salicylic acid (SA) is one of the most commonly used analgesics and blood-thinning agent.
In this reaction, Salicylic acid (SA) is reacting with acetic anhydride.
It leads to the acetylation of the hydroxyl group present in the Salicylic acid (SA), thereby resulting in the production of acetylsalicylic acid i.e., aspirin.

Acetic acid is manufactured as a byproduct of this reaction.
This is also present as one of the impurities during large scale production of aspirin.
These impurities must be removed from the resulting product mixture by several refining processes.

*Esterification Reaction:
Since Salicylic acid (SA) is an organic acid, it undergoes a reaction with organic alcohol groups to produce a new organic chemical class alike ester.
When Salicylic acid (SA) is reacting with methanol in an acidic medium preferably sulphuric acid in the presence of heat, a dehydration reaction occurs with the loss of water −OH− ion.

This ion is lost from the carboxylic acid functional group present in the Salicylic acid (SA) molecule and the H+ ion is lost from the deprotonation of the methanol molecule, resulting in the formation of methyl salicylate (an ester).



METHODS OF PREPARATION OF SALICYLIC ACID (SA):
There are two most common methods in use for the preparation of Salicylic acid (SA) are as follows –

*From Phenol:
When phenol is reacted with sodium hydroxide, Salicylic acid (SA) forms sodium phenoxide.
Sodium phenoxide then undergoes distillation and dehydration.

This process is followed by a carboxylation reaction with carbon dioxide, which results in the formation of sodium salicylate i.e., salt of Salicylic acid (SA).
This salt then further reacted with an acid or hydronium ion or any species that denotes a proton to obtain the Salicylic acid (SA).

*From Methyl Salicylate:
Methyl salicylate also known as oil of wintergreen is commonly called analgesic in the pharmaceutical industry.
It is in use for the preparation of Salicylic acid (SA).

In this reaction, methyl salicylate is reacted with sodium hydroxide (NaOH) to lead to the formation of a sodium salt intermediate of Salicylic acid (SA).
This acid is named disodium salicylate, which upon undergoing further reaction with sulphuric acid leads to the formation of Salicylic acid (SA).



PHYSICAL PROPERTIES OF SALICYLIC ACID (SA):
Salicylic acid (SA) is a colourless, odourless and needle-shaped crystals at room temperature.
The taste of Salicylic acid (SA) is acrid.
The boiling point and melting point of Salicylic acid (SA) are 211oC and 315oC respectively.

The Salicylic acid (SA) molecule has two hydrogen bond donors and three hydrogen bond acceptors.
The flashpoint of Salicylic acid (SA) is 157oC.
Due to Salicylic acid (SA)'s lipophilic nature, its solubility in water is very poor i.e., 1.8 g/L at 25oC.

Salicylic acid (SA) is soluble in organic solvents like carbon tetrachloride, benzene, propanol, ethanol and acetone.
The density ofSalicylic acid (SA) is 1.44 at 20oC.
Salicylic acid (SA)'s vapour pressure is 8.2×105mmHg at 25oC.
Salicylic acid (SA) is a tendency to undergo discolouration when exposed to direct sunlight due to its photochemical degradation.

Salicylic acid (SA)'s heat of combustion is 3.026mj/mole at 25oC.
The pH of a saturated solution of Salicylic acid (SA) is 2.4.
Salicylic acid (SA)'s pka value i.e., dissociation constant is 2.97.



STRUCTURE OF SALICYLIC ACID (SA):
The structural formula of Salicylic acid (SA) is C6H4(OH)COOH.
The chemical formula of Salicylic acid (SA) can also be written as C7H6O3 in the condensed form.
The IUPAC name of Salicylic acid (SA) is 2-hydroxybenzoic acid.

Salicylic acid (SA) has a hydroxyl group i.e., -OH group attached at the ortho position with respect to the carboxylic acid.
This COOH group is present on the benzene ring.
The molecular weight or molar mass of Salicylic acid (SA) is 138.12 g/mol.

All carbon atoms present in the benzene ring of Salicylic acid (SA) are sp2 hybridized.
Salicylic acid (SA) forms an intramolecular hydrogen bond.
In an aqueous solution, Salicylic acid (SA) dissociates to lose a proton from the carboxylic acid.

The resulting carboxylate ion i.e., −COO− undergoes intermolecular interaction with the hydrogen atom of the hydroxyl group i.e., -OH.
Salicylic acid (SA) leads to the formation of an intramolecular hydrogen bond.



CHEMICAL SYNTHESIS OF SALICYLIC ACID (SA):
Commercial vendors prepare sodium salicylate by treating sodium phenolate (the sodium salt of phenol) with carbon dioxide at high pressure (100 atm) and high temperature (115 °C) – a method known as the Kolbe-Schmitt reaction. Acidifying the product with sulfuric acid gives Salicylic acid (SA):
At the laboratory scale, Salicylic acid (SA) can also be prepared by the hydrolysis of aspirin (acetylsalicylic acid) or methyl salicylate (oil of wintergreen) with a strong acid or base; these reactions reverse those chemicals' commercial syntheses.



REACTIONS OF SALICYLIC ACID (SA):
Upon heating, Salicylic acid (SA) converts to phenyl salicylate:
2 HOC6H4CO2H → C6H5O2C6H4OH + CO2 + H2O
Further heating gives xanthone.
Salicylic acid (SA) as its conjugate base is a chelating agent, with an affinity for iron(III).
Salicylic acid (SA) slowly degrades to phenol and carbon dioxide at 200–230 °C:
C6H4OH(CO2H) → C6H5OH + CO2



PRODUCTION AND CHEMICAL REACTIONS OF SALICYLIC ACID (SA):
Biosynthesis:
Salicylic acid (SA) is biosynthesized from the amino acid phenylalanine.
In Arabidopsis thaliana, Salicylic acid (SA) can be synthesized via a phenylalanine-independent pathway.



MECHANISM OF ACTION OF SALICYLIC ACID (SA):
Salicylic acid (SA) modulates COX-1 enzymatic activity to decrease the formation of pro-inflammatory prostaglandins.
Salicylate may competitively inhibit prostaglandin formation. Salicylate's antirheumatic (nonsteroidal anti-inflammatory) actions are a result of its analgesic and anti-inflammatory mechanisms.

Salicylic acid (SA), when applied to the skin surface, works by causing the cells of the epidermis to slough off more readily, preventing pores from clogging up, and allowing room for new cell growth.
Salicylic acid (SA) inhibits the oxidation of uridine-5-diphosphoglucose (UDPG) competitively with NADH and noncompetitively with UDPG.

Salicylic acid (SA) also competitively inhibits the transferring of glucuronyl group of uridine-5-phosphoglucuronic acid to the phenolic acceptor.
The wound-healing retardation action of salicylates is probably due mainly to its inhibitory action on mucopolysaccharide synthesis.



HISTORY OF SALICYLIC ACID (SA):
Willow has long been used for medicinal purposes.
Dioscorides, whose writings were highly influential for more than 1,500 years, used 'Itea' (which was possibly a species of willow) as a treatment for 'painful intestinal obstructions,' birth control, for 'those who spit blood,' to remove calluses and corns and, externally, as a 'warm pack for gout.'
William Turner, in 1597, repeated this, saying that willow bark, 'being burnt to ashes, and steeped in vinegar, takes away corns and other like risings in the feet and toes.'

Some of these cures may describe the action of Salicylic acid (SA), which can be derived from the salicin present in willow.
Salicylic acid (SA) was used in Europe and China to treat these conditions.
This remedy is mentioned in texts from Ancient Egypt, Sumer, and Assyria.

The Cherokee and other Native Americans use an infusion of the bark for fever and other medicinal purposes.
In 2014, archaeologists identified traces of Salicylic acid (SA) on seventh-century pottery fragments found in east-central Colorado.
The Reverend Edward Stone, a vicar from Chipping Norton, Oxfordshire, England, reported in 1763 that the bark of the willow was effective in reducing a fever.

An extract of willow bark, called salicin, after the Latin name for the white willow (Salix alba), was isolated and named by German chemist Johann Andreas Buchner in 1828.
A larger amount of the substance was isolated in 1829 by Henri Leroux, a French pharmacist.

Raffaele Piria, an Italian chemist, was able to convert the substance into a sugar and a second component, which on oxidation becomes Salicylic acid (SA).
Salicylic acid (SA) was also isolated from the herb meadowsweet (Filipendula ulmaria, formerly classified as Spiraea ulmaria) by German researchers in 1839.
Salicylic acid (SA)'s extract causes digestive problems such as gastric irritation, bleeding, diarrhea, and even death when consumed in high doses.

In 1874 the Scottish physician Thomas MacLagan experimented with salicin as a treatment for acute rheumatism, with considerable success, as he reported in The Lancet in 1876.
Meanwhile, German scientists tried sodium salicylate with less success and more severe side effects.

In 1979, salicylates were found to be involved in induced defenses of tobacco against tobacco mosaic virus.
In 1987, Salicylic acid (SA) was identified as the long-sought signal that causes thermogenic plants, such as the voodoo lily, Sauromatum guttatum, to produce heat.



SALICYLIC ACID (SA), SIGNAL TRANSDUCTION:
A number of proteins have been identified that interact with SA in plants, especially Salicylic acid (SA) binding proteins (SABPs) and the NPR genes (nonexpressor of pathogenesis-related genes), which are putative receptors.
Salicylic acid (SA) is an effective inhibitor of COX-2 activity at concentrations far below those required to inhibit NF-κB (20 mg/mL) activation.

Salicylic acid (SA) inhibits prostaglandin E2 release when add together with interleukin 1β for 24 hr with an IC50 value of 5 μg/mL, an effect that is independent of NF-κB activation or COX-2 transcription or translation.
Salicylic acid (SA) acutely (30 min) also causes a concentration-dependent inhibition of COX-2 activity measured in the presence of 0, 1, or 10 μM exogenous arachidonic acid.

In contrast, when exogenous arachidonic acid is increased to 30 μM, Salicylic acid (SA) is a very weak inhibitor of COX-2 activity with an IC50 of >100 μg/mL.
When added together with IL-1β for 24 hr, Salicylic acid (SA) causes a concentration-dependent inhibition of PGE2 release with an apparent IC50 value of approximately 5 μg/mL.

The ability of Salicylic acid (SA) to directly inhibit COX-2 activity in A549 cells is tested after a 30-min exposure period, followed by the addition of different concentrations of exogenous arachidonic acid (1, 10, and 30 μM).
Salicylic acid (SA) causes a concentration-dependent inhibition of COX-2 activity in the absence of added arachidonic acid or in the presence of 1 or 10 μM exogenous substrate with an apparent IC50 value of approximately 5 μg/mL.

However, when the same experiments are performed using 30 μM arachidonic acid, Salicylic acid (SA) is an ineffective inhibitor of COX-2 activity, with an apparent IC50 value of more than 100 μg/mL, and achieves a maximal inhibition of less than 50%.



SALICYLIC ACID (SA), PLANT HORMONE:
Salicylic acid (SA) is a phenolic phytohormone, and is found in plants with roles in plant growth and development, photosynthesis, transpiration, and ion uptake and transport.

Salicylic acid (SA) is involved in endogenous signaling, mediating plant defense against pathogens.
Salicylic acid (SA) plays a role in the resistance to pathogens (i.e. systemic acquired resistance) by inducing the production of pathogenesis-related proteins and other defensive metabolites.

Salicylic acid (SA)'s defense signaling role is most clearly demonstrated by experiments which do away with it: Delaney et al. 1994, Gaffney et al. 1993, Lawton et al. 1995, and Vernooij et al. 1994 each use Nicotiana tabacum or Arabidopsis expressing nahG, for salicylate hydroxylase.
Pathogen inoculation did not produce the customarily high Salicylic acid (SA) levels, SAR was not produced, and no PR genes were expressed in systemic leaves. Indeed, the subjects were more susceptible to virulent – and even normally avirulent – pathogens.

Exogenously, Salicylic acid (SA) can aid plant development via enhanced seed germination, bud flowering, and fruit ripening, though too high of a concentration of Salicylic acid (SA) can negatively regulate these developmental processes.

The volatile methyl ester of Salicylic acid (SA), methyl salicylate, can also diffuse through the air, facilitating plant-plant communication.
Methyl salicylate is taken up by the stomata of the nearby plant, where it can induce an immune response after being converted back to Salicylic acid (SA).



PHYSICAL and CHEMICAL PROPERTIES of SALICYLIC ACID (SA):
Formula : C7H6O3
Molecular weight : 138,12 g/mol
CAS-No. : 69-72-7
EC-No. : 200-712-3
Physical state: powdercrystalline
Color: white
Odor: odorless
Melting point/freezing point:
Melting point/range: 158 - 160 °C
Initial boiling point and boiling range: 211 °C at 27 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Lower explosion limit: 1,1 %(V)
Flash point 157 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 2,4 at 20 °C

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water:
log Pow: 2,25 at 25 °C - Bioaccumulation is not expected.
Vapor pressure: 1 hPa at 114 °C
Density: 1,44 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Chemical Name : 2 – Hydroxybenzoic Acid
Molecular Formula : C7H6O3
Molecular Weight : 138.1
Description : White / colourless, crystalline powder / acicular crystals

CAS No. : 69-72-7
CAS: 69-72-7
MF: C7H6O3
MW: 138.12
EINECS: 200-712-3
Mol File: 69-72-7.mol
Salicylic acid: Chemical Properties
Melting point: 158-161 °C(lit.)
Boiling point: 211 °C(lit.)
density: 1.44
vapor density: 4.8 (vs air)
vapor pressure: 1 mm Hg ( 114 °C)
refractive index: 1,565
FEMA: 3985 | 2-HYDROXYBENZOIC ACID
Fp: 157 °C
storage temp.: 2-8°C
solubility: ethanol: 1 M at 20 °C, clear, colorless
pka: 2.98(at 25℃)

form: Solid
color: White to off-white
PH Range: Non0 uorescence (2.5) to dark blue 0 uorescence (4.0)
Odor: at 100.00 %. faint phenolic nutty
PH: 3.21(1 mM solution);2.57(10 mM solution);2.02(100 mM solution);
Odor Type: nutty
Water Solubility: 1.8 g/L (20 ºC)
Sensitive: Light Sensitive
λmax: 210nm, 234nm, 303nm
Merck: 148,332
JECFA Number: 958
Sublimation: 70 ºC
BRN: 774890
Stability: Stable.
InChIKey: YGSDEFSMJLZEOE-UHFFFAOYSA-N

LogP: 2.01
CAS DataBase Reference: 69-72-7(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 2-hydroxy-(69-72-7)
EPA Substance Registry System: Salicylic acid (69-72-7)
IUPAC Name: 2-hydroxybenzoic acid
Molecular Weight: 138.12
Molecular Formula: C7H6O3
Canonical SMILES: C1=CC=C(C(=C1)C(=O)O)O
InChI: InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChIKey: YGSDEFSMJLZEOE-UHFFFAOYSA-N
Boiling Point: 211 ℃ (20 mmHg)
Melting Point: 154-156 ℃
Flash Point: 157ºC
Purity: > 98 %
Density: 1.44 g/cm3

Solubility: Solubility (weight percent):
carbon tetrachloride 0.262 (25 °C);
benzene 0.775 (25 °C); propanol 27.36 (21 °C);
absolute ethanol 34.87 (21 °C); acetone 396 (23 °C)
Appearance: White poder
Storage: Store at RT.
EINECS: 200-712-3
Hazard Codes: Xn
HS Code: 2918211000
Log P: 1.09040
MDL: MFCD00002439
pH: pH of saturated solution: 2.4
PSA: 57.53
Quality Standard: Enterprise Standard
Refractive Index: 1.565
Risk Statements: R22; R36/37/38; R41

RTECS: VO0525000
Safety Statements: S26-S37/39
Stability: Stable.
Vapor Density: 4.8
Vapor Pressure: 1 mm Hg ( 114 °C)
Odour: Almost Odourless.
Melting Range: 158.5°C to 161.0°C.
Appearance of Solution/
Clarity & Colour of Solution: Passes test as per B.P./I.P.
Heavy Metals: 20 ppm (max)
Sulphated Ash/Residue on Ignition: 0.1% w/w (I.P./B.P.Limit) / 0.05% w/w (U.S.P. Limit)
Chloride: 125 ppm (max.) I.P./100 ppm (max.) B.P.
Sulphate: 0.02% (max.) I.P./140 ppm U.S.P.
Related Substance: Complies with the B.P. test.
Loss of Drying: 0.5% (max.) B.P.

Iron: 2 ppm (max.) I.P.
Molecular Weight: 138.12 g/mol
XLogP3: 2.3
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 1
Exact Mass: 138.031694049 g/mol
Monoisotopic Mass: 138.031694049 g/mol
Topological Polar Surface Area: 57.5Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 133
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0

Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
CAS number: 69-72-7
EC number: 200-712-3
Hill Formula: C₇H₆O₃
Chemical formula: HOC₆H₄COOH
Molar Mass: 138.12 g/mol
HS Code: 2918 21 10
Boiling point: 211 °C (1013 hPa)
Density: 1.44 g/cm3 (20 °C)
Flash point: 157 °C
Ignition temperature: 500 °C
Melting Point: 158 - 160 °C
pH value: 2.4 (H₂O, 20 °C) (saturated solution)
Vapor pressure: 1 hPa (114 °C)
Bulk density: 400 - 500 kg/m3
Solubility: 2 g/l
Chemical formula: C7H6O3
Molar mass: 138.122 g/mol
Appearance: Colorless to white crystals

Odor: Odorless
Density: 1.443 g/cm3 (20 °C)
Melting point: 158.6 °C (317.5 °F; 431.8 K)
Boiling point: 211 °C (412 °F; 484 K) at 20 mmHg
Sublimation conditions: Sublimes at 76 °C
Solubility in water:
1.24 g/L (0 °C)
2.48 g/L (25 °C)
4.14 g/L (40 °C)
17.41 g/L (75 °C)
77.79 g/L (100 °C)
Solubility: Soluble in ether, CCl4, benzene, propanol,
acetone, ethanol, oil of turpentine, toluene
Solubility in benzene:
0.46 g/100 g (11.7 °C)
0.775 g/100 g (25 °C)
0.991 g/100 g (30.5 °C)
2.38 g/100 g (49.4 °C)
4.4 g/100 g (64.2 °C)

Solubility in chloroform:
2.22 g/100 mL (25 °C)
2.31 g/100 mL (30.5 °C)
Solubility in methanol:
40.67 g/100 g (−3 °C)
62.48 g/100 g (21 °C)
Solubility in olive oil: 2.43 g/100 g (23 °C)
Solubility in acetone: 39.6 g/100 g (23 °C)
log P: 2.26
Vapor pressure: 10.93 mPa
Acidity (pKa):
2.97 (25 °C)
13.82 (20 °C)
UV-vis (λmax): 210 nm, 234 nm, 303 nm (4 mg/dL in ethanol)
Magnetic susceptibility (χ): −72.23·10−6 cm3/mol
Refractive index (nD): 1.565 (20 °C)
Dipole moment: 2.65 D

Thermochemistry:
Std enthalpy of formation (ΔfH⦵298): −589.9 kJ/mol
Std enthalpy of combustion (ΔcH⦵298): -3.025 MJ/mol
CAS: 69-72-7
MF: C7H6O3
MW: 138.12
EINECS: 200-712-3
Mol File: 69-72-7.mol
Salicylic acid Chemical Properties
Melting point: 158-161 °C(lit.)
Boiling point: 211 °C(lit.)
density: 1.44
vapor density: 4.8 (vs air)
vapor pressure: 1 mm Hg ( 114 °C)
refractive index: 1,565
FEMA: 3985 | 2-HYDROXYBENZOIC ACID
Fp: 157 °C

storage temp.: 2-8°C
solubility: ethanol: 1 M at 20 °C, clear, colorless
pka: 2.98(at 25℃)
form: Solid
color: White to off-white
PH Range: Non0 uorescence (2.5) to dark blue 0 uorescence (4.0)
Odor: at 100.00 %. faint phenolic nutty
PH: 3.21(1 mM solution);2.57(10 mM solution);2.02(100 mM solution);
Odor Type: nutty
Water Solubility: 1.8 g/L (20 ºC)
Sensitive: Light Sensitive
λmax: 210nm, 234nm, 303nm
Merck: 148,332
JECFA Number: 958
Sublimation: 70 ºC
BRN: 774890
Stability:: Stable. S
ubstances to be avoided include oxidizing agents, strong bases, iodine, fluorine.
Sensitive to light.

InChIKey: YGSDEFSMJLZEOE-UHFFFAOYSA-N
LogP: 2.01
CAS DataBase Reference: 69-72-7(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 2-hydroxy-(69-72-7)
EPA Substance Registry System: Salicylic acid (69-72-7)
IUPAC: SALICYLICACID
CAS Number: 69-72-7
Molecular Weight: 138.122
Formula: C7H6O3
SMILES: OC(=O)C1=C(O)C=CC=C1
Preferred IUPAC Name: 2-HYDROXYBENZOIC ACID
InChIKey: InChIKey=YGSDEFSMJLZEOE-UHFFFAOYSA-N
Melting Point: 158°C
Color: White
pH: 3.6
Boiling Point: 211°C
Formula Weight: 138.12g/mol
Vapor Pressure: 0.3mbar 95
Physical Form: Solid

CAS number: 69-72-7
EC number: 200-712-3
Hill Formula: C₇H₆O₃
Chemical formula: HOC₆H₄COOH
Molar Mass: 138.12 g/mol
HS Code: 2918 21 10
Boiling point: 211 °C (1013 hPa)
Density: 1.44 g/cm3 (20 °C)
Flash point: 157 °C
Ignition temperature: 500 °C
Melting Point: 158 - 160 °C
pH value: 2.4 (H₂O, 20 °C) (saturated solution)
Vapor pressure: 1 hPa (114 °C)
Bulk density: 400 - 500 kg/m3
Solubility: 2 g/l
CAS number: 69-72-7
Weight Average: 138.1207
Monoisotopic: 138.031694058
InChI Key: YGSDEFSMJLZEOE-UHFFFAOYSA-N

InChI: InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
IUPAC Name: 2-hydroxybenzoic acid
Traditional IUPAC Name: salicylic
Chemical Formula: C7H6O3
SMILES: OC(=O)C1=CC=CC=C1O
Appearance: white powder (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 158.00 to 161.00 °C. @ 760.00 mm Hg
Boiling Point: 211.00 °C. @ 20.00 mm Hg
Boiling Point: 336.00 to 337.00 °C. @ 760.00 mm Hg
Vapor Pressure: 1.000000 mmHg @ 114.00 °C.
Vapor Density: 4.8 ( Air = 1 )
Flash Point: > 212.00 °F. TCC ( > 100.00 °C. )
logP (o/w): 2.260
Soluble in: alcohol
water, 3808 mg/L @ 25 °C (est)
water, 2240 mg/L @ 25 °C (exp)



FIRST AID MEASURES of SALICYLIC ACID (SA):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of SALICYLIC ACID (SA):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of SALICYLIC ACID (SA):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of SALICYLIC ACID (SA):
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of SALICYLIC ACID (SA):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Store at Room Temperature.
Light sensitive



STABILITY and REACTIVITY of SALICYLIC ACID (SA):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available



SALICYLIC ACID PHARMA GRADE
Salicylic acid pharma grade is an important organic synthetic raw material, widely used in medicine, pesticides, dyes, rubber, food and perfumes.
In the pharmaceutical industry, the main drug productions of Salicylic acid pharma grade are sodium salicylate, wintergreen oil (methyl salicylate), aspirin (acetylsalicylic acid), salicylic acid amine, phenyl salicylate.
In dye industry, Salicylic acid pharma grade is used for production mordant pure yellow , direct yellow 3GN, direct yellow GR, direct brown 3GN, acid mordant brown G, acid mordant yellow GG, acid yellow dye complex.

CAS: 69-72-7
MF: C7H6O3
MW: 138.12
EINECS: 200-712-3

Synonyms
2-HYDROXYBENZOIC ACID;ACIDUM SALICYLICUM;ACETYLSALISYLIC ACID IMP C;ACETYLSALICYLIC ACID IMPURITY C;FEMA 3985;SALICYCLIC ACID;SALICYLIC ACID;RETARDER TSA
salicylic acid;2-Hydroxybenzoic acid;69-72-7;o-hydroxybenzoic acid;2-Carboxyphenol;o-Carboxyphenol;Rutranex;Salonil;Retarder W;Duoplant;Keralyt;Psoriacid-S-stift;Freezone;Saligel;Ionil;Salicylic acid soap;Stri-Dex;Verrugon;Salicylic acid collodion;Benzoic acid, 2-hydroxy-;Acidum salicylicum;Trans-Ver-Sal;2-Hydroxybenzenecarboxylic acid;Phenol-2-carboxylic acid;Orthohydroxybenzoic acid;Acido salicilico;Kyselina salicylova;Salicylic acid, tech.;Duofilm;Salicyclic acid;Ionil-Plus;Dr. Scholl's callus removers;Clear away wartremover;Duofilwartremover;Domerine;Occlusal;Sebucare;Sebulex;Mediplast pads;Akurza Lotion;Hydrisalic Gel;Kyselina 2-hydroxybenzoova;Akurza Cream;Ionil plus;Salex Lotion;Salex Cream;DuoPlant Gel;Caswell No. 731;Dr. Scholl's corn removers;Kyselina salicylova [Czech];salicylicum acidum;DHS Sal Shampoo;P&S Shampoo;Dr. Scholl's wart remover kit;Durasal;Acido salicilico [Italian];NSC 180;Advanced pain relief corn removers;Acido o-idrossibenzoico;2-hydroxy-benzoic acid;Kyselina 2-hydroxybenzoova [Czech];Benzoic acid, hydroxy-;Advanced pain relief callus removers;CCRIS 6714;HSDB 672;Acido o-idrossibenzoico [Italian];AI3-02407;Propa pH Peel-Off Acne Mask;Salicylic acid & Sulfur Soap;EPA Pesticide Chemical Code 076602;Anti-blemish;CHEBI:16914;BRN 0774890;NSC-180;UNII-O414PZ4LPZ;EINECS 200-712-3;O414PZ4LPZ;MFCD00002439;DTXSID7026368;FEMA NO. 3985;Bazuka Extra Strength Gel;CHEMBL424;Salicylic acid [USP:JAN];MLS000069653;DTXCID206368;NSC180;K 537;EC 200-712;29656-58-4;ATA fraction 10, ammonium salt;NCGC00159447-05;SMR000059163;Acid, Salicylic;ortho-Hydroxybenzoic Acid;Salicylic acid (USP:JAN);SALICYLIC ACID (USP);SALICYLIC ACID [USP];o Hydroxybenzoic Acid;SALICYLIC ACID (MART.);SALICYLIC ACID [MART.]

In pesticide production, Salicylic acid pharma grade is used for the synthesis of organic phosphorus pesticide Isocarbophos, intermediate isopropyl salicylate isofenphos methyl and Rodenticide warfarin, coumatetralyl intermediate 4-hydroxycoumarin.
In rubber industry, Salicylic acid pharma grade is used as anti scorching agent and production of ultraviolet absorbent and foaming agent.
Salicylic acid pharma grade is perfume material, used for the preparation of methyl salicylate, salicylic acid ethyl ester; food preservatives, its sodium Salt is mostly used, now a number of countries have been banned; methyl salicylate can be used as oral cleaning agents, such as toothpaste flavor.
Salicylic acid pharma grade (from Latin salix, willow tree, from the bark of which the substance used to be obtained) is a mono hydroxy benzoic acid, a type of phenolic acid and a beta hydroxy acid.
This colorless crystalline organic acid is widely used in organic synthesis and functions as a plant hormone.

Salicylic acid pharma grade is derived from the metabolism of salicin.
In addition to being an important active metabolite of aspirin (acetylsalicylic acid), which acts in part as a prod rug to salicylic acid, Salicylic acid pharma grade is probably best known for its use in anti-acne treatments.
The salts and esters of salicylic acid are known as salicylates.
A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position.
Salicylic acid pharma grade is obtained from the bark of the white willow and wintergreen leaves.
A crystalline aromatic carboxylic acid.
Salicylic acid pharma grade is used in medicines, as an antiseptic, and in the manufacture of azo dyes.
Salicylic acid pharma grade's ethanoyl (acetyl) ester is aspirin.

Salicylic acid pharma grade Chemical Properties
Melting point: 158-161 °C(lit.)
Boiling point: 211 °C(lit.)
Density: 1.44
Vapor density: 4.8 (vs air)
Vapor pressure: 1 mm Hg ( 114 °C)
Refractive index: 1,565
FEMA: 3985 | 2-HYDROXYBENZOIC ACID
Fp: 157 °C
Storage temp.: 2-8°C
Solubility ethanol: 1 M at 20 °C, clear, colorless
pka: 2.98(at 25℃)
Form: Solid
Color: White to off-white
PH Range: Non0 uorescence (2.5) to dark blue 0 uorescence (4.0)
Odor: at 100.00 %. faint phenolic nutty
PH: 3.21(1 mM solution);2.57(10 mM solution);2.02(100 mM solution);
Odor Type: nutty
Water Solubility: 1.8 g/L (20 ºC)
Sensitive: Light Sensitive
λmax: 210nm, 234nm, 303nm
Merck: 14,8332
JECFA Number: 958
Sublimation: 70 ºC
BRN: 774890
Stability:: Stable. Substances to be avoided include oxidizing agents, strong bases, iodine, fluorine. Combustible. Sensitive to light.
InChIKey: YGSDEFSMJLZEOE-UHFFFAOYSA-N
LogP: 2.01
CAS DataBase Reference: 69-72-7(CAS DataBase Reference)
NIST Chemistry Reference: Salicylic acid pharma grade(69-72-7)
EPA Substance Registry System: Salicylic acid pharma grade (69-72-7)

Salicylic acid pharma grade is a white powder with an acrid taste that is stable in air but gradually discolored by light.
Soluble in acetone, oil of turpentine, alcohol, ether,benzene; slightly soluble in water,and combustible.
Derived by reacting a hot solution of sodium phenolate with carbon dioxide and acidifying the sodium salt thus formed.
Used in the manufacture of aspirin and salicylates, resins, dyestuff intermediate, prevulcanization inhibitor, analytical reagent,and fungicide.
Salicylic acid pharma grade has the formula C6H4(OH) COOH, where the OH group is ortho to the carboxyl group.
Salicylic acid pharma grade is also known as 2- hydroxybenzoic acid.
Salicylic acid pharma grade is poorly soluble in water (2 g / L at 20 °C).
Salicylic acid pharma grade can be prepared by the esterification of the phenolic hydroxyl group of salicylic acid with the acetyl group from acetic anhydride or acetyl chloride.

Physical properties
Appearance: white crystalline powder.
Solubility: Absolutely soluble in ethanol, soluble in ether and chloroform, slightly soluble in water and anhydrous ether.
Stability: Stable at room temperature, discomposes into phenol and carbon dioxide after rapidly heated.
Salicylic acid pharma grade’s partially acidic.
Appearance: white crystal and decomposes at 136–140°C.
Melting point: 136°C.
Aspirin is the acetyl derivative of salicylic acid with weak acidity.
Salicylic acid pharma grade's acidity coefficient is 3.5 at 25°C.
Stability: Aspirin decomposes rapidly in ammonium acetate, alkali metal of acetate, carbonate, citrate or hydroxide solutions.
There are two crystal forms of aspirin including crystal form I and II.

Salicylic acid pharma grade has sterilization ability, 2.5% alcohol solution (called spiritus) is used as a topical medicine in the treatment of tinea manus and tinea pedis, also can be made into ointment.
Salicylic acid pharma grade can be used for food preservative or preservatives, also can be used for the preparation of toothpaste, mouthwash.
Salicylic acid pharma grade has antipyretic and analgesic effects, can cure rheumatism and so on.
Salicylic acid pharma grade's all esters can be used as drug and spices.
Salicylic acid pharma grade has pleasant aromas of holly, is used for the preparation of perfume and soap flavor.
The methyl salicylate is coated on the skin, can penetrate into the muscle and let out of Salicylic acid pharma grade to release local pain, so it also can be used for the treatment of pain, contusion, sprain and other medication.
Salicylic acid pharma grade has orchid aroma, benzyl salicylate has weak ester aroma, both can prepare perfume or soap flavor.
The common name of Salicylic acid pharma grade is Salo, was hydrolyzed into phenol and salicylic acid in the intestine , is a kind of effective enteral preservatives.
Another Kind drug related to Salicylic acid pharma grade is para aminosalicylic acid (PAS, see "Para amino salicylic acid), Its sodium and calcium salts are used as anti TB drugs for acute exudative pulmonary tuberculosis (TB) and mucosal tuberculosis, is a weak antimicrobial drug, the effect is only 2% of streptomycin, often combined with streptomycin and isoniazid , in order to enhance the curative effect.
Salicylic acid pharma grade can be acetylated to the aspirin.

Uses
Salicylic acid pharma grade is an FDA approved skin care ingredient used for the topical treatment of acne, and it's the only beta hydroxy acid (BHA) used in skin care products.
Perfect for oily skin, Salicylic acid pharma grade is best known for its ability to deep clean excess oil out of pores and reduce oil production moving forward.
Because Salicylic acid pharma grade keeps pores clean and unclogged, it prevents future whiteheads and blackheads from developing.
Salicylic acid pharma grade also exfoliates dead skin, and its anti-inflammatory properties make it a prime ingredient for those with psoriasis.
Salicylic acid pharma grade naturally occurs in willow bark, sweet birch bark, and wintergreen leaves, but synthetic versions are also used in skin care products.

Salicylic acid pharma grade is widely used, eczema, psoriasis, salicylic acid can be used in acne, dandruff.
The concentration of 3%~6% can be used to horny, higher than 6% of Salicylic acid pharma grade can damage to tissue.
Below 40% of concentration is suitable for the treatment of thick cocoon, corns and warts. Salicylic acid pharma grade can also be added in the treatment of acne and dandruff.
Nowadays many famous cosmetic ingredients: in 1993, Clinique CLINIQUE first launched 1% Salicylic acid pharma grade in soft water cream, immediately became one of Clinique's most successful products; In 1998, SK-II crystal induced skin cream added 1.5%BHA ingredients to the original, and salicylic acid has effect of treatment pores and cutin like the egg peeling analogy that caused the market boom; open access Olay popular products activating cream also contains 1.5% BHA components.
However, due to the high concentration of Salicylic acid pharma grade, it has a certain degree of damage, cosmetics containing Salicylic acid pharma grade concentration has generally been limited between 0.2%~1.5%, containing Salicylic acid pharma grade cosmetics shall be added to the note of warning signs to determine the safety of long-term use and children under 3 years of age also shall not be used.

Although toxic in large quantities, Salicylic acid pharma grade is used as a food preservative and as bactericidal and an antiseptic.
For some people with salicylate sensitivity even these small doses can be harmful.
Salicylic acid pharma grade is a useful phosphor in the vacuum ultraviolet with nearly flat quantum efficiency for wavelengths between 10 to 100 nm.
Salicylic acid pharma grade fluoresces in the blue at 420 nm.
Salicylic acid pharma grade is easily prepared on a clean surface by spraying a saturated solution of the salt in methanol followed by evaporation.

Salicylic acid pharma grade is a beta-hydroxy acid with keratolytic and antiinflammatory activity.
Salicylic acid pharma grade helps dissolve the top layer of stratum corneum cells, improving the look and feel of the skin.
Salicylic acid pharma grade is an effective ingredient in acne products and as such is widely used in acne soaps and lotions.
Because Salicylic acid pharma grade is lipid soluble, it can more easily reduce sebaceous follicle blockage by penetrating the pores and exfoliating the cellular buildup.
Salicylic acid pharma grade is antimicrobial, anti-septic, enhances the activity of preservatives, and can be used to adjust the pH of products.
For the treatment of aging skin, Salicylic acid pharma grade appears to help improve skin wrinkles, roughness, and tone.

In addition, Salicylic acid pharma grade is a useful ingredient for products formulated to treat psoriasis, callouses, corns, and warts-cases where there is a buildup of dead skin cells.
When applied topically, it is reported to penetrate 3 to 4 mm into the epidermis.
A small amount of Salicylic acid pharma grade can convert to copper salicylate, a powerful anti-inflammatory.
used at high concentrations, salicylic acid may cause skin redness and rashes.
Salicylic acid pharma grade is a naturally occurring organic acid, related to aspirin.
Salicylic acid pharma grade is found in some plants, particularly the leaves of wintergreen, willow bark, and the bark of sweet birch.
Salicylic acid pharma grade is also synthetically manufactured.

Salicylic acid pharma grade is known for its ability to ease aches and pains and reduce fevers.
These medicinal properties, particularly fever relief, have been known since ancient times, and Salicylic acid pharma grade is used as an antiinflammatory drug.
In modern medicine, Salicylic acid pharma grade and its derivatives are used as constituents of some rubefacient products.
For example, methyl salicylate is used as a liniment to soothe joint and muscle pain, and choline salicylate is used topically to relieve the pain of mouth ulcers.
As with other beta hydroxy acids, Salicylic acid pharma grade is a key ingredient in many skin-care products for the treatment of seborrhoeic dermatitis, acne, psoriasis, calluses, corns, keratosis pilaris, and warts.

Pharmacology
Aspirin is a nonsteroidal anti-inflammatory drug (NSAID).
The main pharmacological effect is to inhibit prostaglandin metabolism and thromboxane synthesis by inhibiting prostaglandin metabolism-required cyclooxygenase, via irreversible acetylation of 530 serine residues in the hydroxyl of COX-1 polypeptide chain, which results in COX-1 inactivation, blocks the conversion of arachidonic acid into thromboxane A2 pathway and then inhibits the platelet aggregation.
Prostaglandin is a hormone produced locally in the body.
Salicylic acid pharma grade can pass the pain to the brain, regulate body temperature in the hypothalamus and cause inflammation.
Inhibition of prostaglandin synthesis can have antipyretic, analgesic, antiinflammatory and antirheumatic effects.
The adverse effects of aspirin are mainly gastrointestinal symptoms such as nausea, vomiting, upper abdominal discomfort or pain.
Salicylic acid pharma grade can also cause allergic reactions, cardiotoxicity, liver and kidney damage and Wright’s syndrome.
In addition, high doses of aspirin can cause Salicylic acid pharma grade reactions such as headache, dizziness, tinnitus, hearing loss and other central nervous system symptoms.

Clinical Use
The clinical application of aspirin varies with the therapeutic dose.
Low-dose aspirin (75–300mg/day) has antiplatelet aggregation effect and can be used to prevent and treat the coronary and cerebrovascular thrombosis and other postoperative thrombosis.
The middle dose of aspirin (0.5–3 g/day) has antipyretic analgesic effects, so Salicylic acid pharma grade is commonly used in the treatment of fever, headache, toothache, neuralgia, muscle pain and menstrual pain.
High doses of aspirin (more than 4g/day) have anti-inflammatory and antirheumatic effects for the treatment of acute rheumatic fever and rheumatoid arthritis.
In addition, aspirin is used for the treatment of skin and mucous membrane lymphadenopathy (Kawasaki disease) in paediatric.

Indications
Salicylic acid pharma grade is a β-hydroxy acid that penetrates into the sebaceous gland and has comedolytic and anti-inflammatory properties.
Salicylic acid pharma grade can be used as an adjunctive therapy and is found in cleansers, toners, masks, and peels.
Salicylic acid pharma grade is keratolytic and at concentrations between 3% and 6% causes softening of the horny layers and shedding of scales.
Salicylic acid pharma grade produces this desquamation by solubilizing the intercellular cement and enhances the shedding of corneocytes by decreasing cell-to-cell cohesion.
In concentrations >6%, it can be destructive to tissue.
Application of large amounts of the higher concentration of Salicylic acid pharma grade can also result in systemic toxicity.
Salicylic acid pharma grade is used in the treatment of superficial fungal infections, acne, psoriasis, seborrheic dermatitis, warts, and other scaling dermatoses.
When Salicylic acid pharma grade is combined with sulfur, some believe that a synergistic keratolytic effect is produced.
Common preparations include a 3% and 6% ointment with equal concentration of sulfur; 6% propylene glycol solution (Keralyt); 5% to 20% with equal parts of lactic acid in flexible collodion for warts (Duofilm, Occlusal); in a cream base at any concentration for keratolytic effects; as a 60% ointment for plantar warts; and in a 40% plaster on velvet cloth for the treatment of calluses and warts (40% salicylic acid plaster).

Benefits for Skin
Salicylic acid pharma grade is a beta hydroxy acid that also sloughs dead cell buildup within the follicle, acts as a mild antibacterial, and has soothing properties.
Salicylic acid pharma grade is regarded to be less irritating than benzoyl peroxide and has less allergy potential, but it is also less aggressive in treating acne.
Salicylic acid pharma grade is often used for treating milder forms of acne.
The concentration in OTC drugs is limited to 2 percent.
Salicylic acid pharma grade is also used as a performance ingredient exfoliant in smaller concentrations, without making a drug claim.

Methods of production
1. The phenol and sodium hydroxide react to produce phenol sodium, distillation and dehydration, CO2 carboxylation reaction to obtain sodium salicylate, then using sulfuric acid and produce crude product.
The crude product through the sublimation refined to the finished product.
Raw materials consumption quota: phenol (98%) 704kg/t, alkali burn (95%) 417kg/t, sulfate (95%) 500kg/t, carbon dioxide (99%) 467kg/t.

2.The preparation method of the method is that the sodium salt of phenol and carbon dioxide can be obtained by acidification.
phenol and liquid caustic soda are produced into solution of the sodium salt of phenol, vacuum drying, and then to 100℃, slowly put to the dry carbon dioxide, when the pressure reaches 0.7~0.8MPa, stop passing carbon dioxide, warming up to 140 to 180℃.
After the reaction with water, sodium salicylate dissolved and decolorization, filtering, coupled with the sulfuric acid, namely precipitation salicylic acid, after filtering, washing and drying to obtain the product.
Salicylic acid may be obtained (1) from oil of wintergreen, which contains methyl salicylate, or (2) by heating dry sodium phenate C6H5ONa plus carbon dioxide under pressure at 130 °C (266 °F) and recovering from the resulting sodium salicylate by adding dilute sulfuric acid.

Production Methods
Salicylic acid pharma grade is biosynthesized from the amino acid phenylalanine.
In Arabidopsis thaliana it can also be synthesized via a phenylalanine - independent pathway.
Salicylic acid pharma grade is commercially prepared by treating sodium phenolate ( the sodium salt of phenol ) with carbon dioxide at high pressure (100 atm ) and high temperature (390K) -a method known as the Kolbe-Schmitt reaction.
Acidification of the product with sulfuric acid gives salicylic acid :
Salicylic acid pharma grade can also be prepared by the hydrolysis of aspirin (acetylsalicylic acid) or methyl salicylate (oil of winter green) with a strong acid or base.

Reactivity Profile
Salicylic acid pharma grade is a carboxylic acid.
Salicylic acid pharma grade's donate hydrogen ions if a base is present to accept them.
They react in this way with all bases, both organic (for example, the amines) and inorganic.
Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat.
Neutralization between an acid and a base produces water plus a salt.
Salicylic acid pharma grade's with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water.
Soluble Salicylic acid pharma grade dissociate to an extent in water to yield hydrogen ions.
The pH of solutions of Salicylic acid pharma grade's is therefore less than 7.0.

Many insoluble Salicylic acid pharma grade's react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt.
Salicylic acid pharma grade's in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt.
Such reactions occur in principle for solid Salicylic acid pharma grade's as well, but are slow if the solid acid remains dry.
Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in Salicylic acid pharma grade to corrode or dissolve iron, steel, and aluminum parts and containers.
Salicylic acid pharma grade's, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide.
The reaction is slower for dry, solid carboxylic acids.
Insoluble Salicylic acid pharma grade's react with solutions of cyanides to cause the release of gaseous hydrogen cyanide.

Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides.
Salicylic acid pharma grade's, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat.
Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat.
Like other organic compounds, Salicylic acid pharma grade's can be oxidized by strong oxidizing agents and reduced by strong reducing agents.
These reactions generate heat.
A wide variety of products is possible.
Like other acids, Salicylic acid pharma grade's may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions.
SALICYLIC ACID PHARMA GRADE
Salicylic Acid Pharma Grade is a white crystalline powder.
Salicylic Acid Pharma Grade is an organic compound with the formula HOC6H4COOH.


CAS-Number: 69-72-7
EC Number: 200-712-3
MDL number: MFCD00002439
Chemical Name: 2 – Hydroxybenzoic Acid
Linear Formula: 2-(HO)C6H4CO2H
Molecular Formula: C7H6O3


A colorless, bitter-tasting solid, Salicylic Acid Pharma Grade is a precursor to and a metabolite of aspirin (acetylsalicylic acid).
Salicylic Acid Pharma Grade is a plant hormone, and has been listed by the EPA Toxic Substances Control Act (TSCA) Chemical Substance Inventory as an experimental teratogen.


The name of it is from Latin salix for willow tree, from which Salicylic Acid Pharma Grade was initially identified and derived.
Salicylic Acid Pharma Grade is an ingredient in some anti-acne products.
Salts and esters of Salicylic Acid Pharma Grade are known as salicylates.


Salicylic Acid Pharma Grade is a white crystalline powder.
Salicylic Acid Pharma Grade is an organic compound with the formula HOC6H4COOH.
Bismuth subsalicylate, a salt of bismuth and Salicylic Acid Pharma Grade, "displays anti-inflammatory action (due to salicylic acid) and also acts as an antacid and mild antibiotic".


Salicylic Acid Pharma Grade is the active ingredient in stomach-relief aids such as Pepto-Bismol and some formulations of Kaopectate.
Salicylic Acid Pharma Grade is a metabolite found in or produced by Escherichia coli.
Salicylic Acid Pharma Grade is a beta hydroxy acid that occurs as a natural compound in plants.


Salicylic Acid Pharma Grade has direct activity as an anti-inflammatory agent and acts as a topical antibacterial agent due to its ability to promote exfoliation.
Salicylic Acid Pharma Grade is obtained from the bark of the white willow and wintergreen leaves.


Salicylic Acid Pharma Grade has bacteriostatic, fungicidal, and keratolytic actions.
Salicylic Acid Pharma Grade is an odorless white to light tan solid.
Salicylic Acid Pharma Grade sinks and mixes slowly with water.


Salicylic Acid Pharma Grade is a monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position.
Salicylic Acid Pharma Grade is obtained from the bark of the white willow and wintergreen leaves.
Salicylic Acid Pharma Grade has a role as an antiinfective agent, an antifungal agent, a keratolytic drug, an EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor, a plant metabolite, an algal metabolite and a plant hormone.


Salicylic Acid Pharma Grade is a conjugate acid of a salicylate.
Salicylic Acid Pharma Grade is obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically.
Salicylic Acid Pharma Grade has bacteriostatic, fungicidal, and keratolytic actions.


Salicylic Acid Pharma Grade is a high-quality, pharmaceutical-grade chemical that plays a crucial role in multiple industries.
Salicylic Acid Pharma Grade is a white, crystalline powder or white or colourless, acicular crystals.
Salicylic Acid Pharma Grade is not hygroscopic.


Salicylic Acid Pharma Grade is best known for the treatment of dermatitis, acne, psoriasis, calluses, and more.
Salicylic Acid Pharma Grade works as a keratotic, comedolytic, and bacteriostatic agent, causing the cells of the epidermis to shed more readily, opening clogged pores and neutralizing the bacteria within.


Salicylic Acid Pharma Grade is a natural product extract from Willow bark, well known as an antiinflammatory inhibitor of cyclooxygenase activity.
Salicylic Acid Pharma Grade is a white or almost white, crystalline powder or colorless crystals.



USES and APPLICATIONS of SALICYLIC ACID PHARMA GRADE:
Salicylic Acid Pharma Grade is used as a medicine to help remove the outer layer of the skin.
As such Salicylic Acid Pharma Grade is used to treat warts, skin tags, calluses, psoriasis, dandruff, acne, ringworm, and ichthyosis.
For conditions other than warts, Salicylic Acid Pharma Grade is often used together with other medications.


Salicylic Acid Pharma Grade is applied to the area affected.
Uses of Salicylic Acid Pharma Grade in manufacturing: Salicylic Acid Pharma Grade is used as a food preservative, a bactericide, and an antiseptic.
Salicylic Acid Pharma Grade is used in the production of other pharmaceuticals, including 4-aminosalicylic acid, sandulpiride, and landetimide (via salethamide).


Salicylic Acid Pharma Grade's salts, the salicylates, are used as analgesics.
Salicylic Acid Pharma Grade has long been a key starting material for making acetylsalicylic acid (aspirin).
Aspirin (acetylsalicylic acid or ASA) is prepared by the esterification of the phenolic hydroxyl group of Salicylic Acid Pharma Grade with the acetyl group from acetic anhydride or acetyl chloride.


ASA is the standard to which all the other non-steroidal anti-inflammatory drugs (NSAIDs) are compared.
In veterinary medicine, this group of drugs is mainly used for treatment of inflammatory musculoskeletal disorders.
Bismuth subsalicylate, a salt of bismuth and Salicylic Acid Pharma Grade, "displays anti-inflammatory action (due to salicylic acid) and also acts as an antacid and mild antibiotic".


Salicylic Acid Pharma Grade is the active ingredient in stomach-relief aids such as Pepto-Bismol and some formulations of Kaopectate.
Other derivatives of Salicylic Acid Pharma Grade include methyl salicylate used as a liniment to soothe joint and muscle pain and choline salicylate used topically to relieve the pain of mouth ulcers.


Salicylic Acid Pharma Grade, when applied to the skin surface, works by causing the cells of the epidermis to slough off more readily, preventing pores from clogging up, and allowing room for new cell growth.
Salicylic Acid Pharma Grade inhibits the oxidation of uridine-5-diphosphoglucose (UDPG) competitively with NADH and noncompetitively with UDPG.


Salicylic Acid Pharma Grade also competitively inhibits the transferring of glucuronyl group of uridine-5-phosphoglucuronic acid to the phenolic acceptor.
The wound-healing retardation action of salicylates is probably due mainly to Salicylic Acid Pharma Grade's inhibitory action on mucopolysaccharide synthesis.


With its impeccable purity and exceptional effectiveness, this versatile chemical, Salicylic Acid Pharma Grade, is widely used in pharmaceutical, cosmetic, and industrial applications.
Salicylic Acid Pharma Grade is meticulously engineered to meet the highest industry standards.


Salicylic Acid Pharma Grade's pharmaceutical-grade quality guarantees its reliability and safety for use in various domains.
This exceptional chemical finds Salicylic Acid Pharma Grade's application in pharmaceuticals, cosmetics, and a wide range of industrial processes.
Salicylic Acid Pharma Grade's blemish-free purity and high effectiveness make it indispensable in the pharmaceutical industry.


Salicylic Acid Pharma Grade demonstrates excellent antiseptic properties, serving as a key ingredient in various medications that fight against infections.
Additionally, Salicylic Acid Pharma Grade's anti-inflammatory and analgesic properties contribute to its widespread usage in pain-relief products.
The cosmetic industry benefits from Salicylic Acid Pharma Grade's extraordinary skin exfoliating abilities.


Its high solubility makes Salicylic Acid Pharma Grade an ideal choice for creating products designed to remove dead skin cells, unclog pores, and reduce acne.
With its potent efficacy, Salicylic Acid Pharma Grade plays a significant role in achieving healthier and smoother skin.


Moreover, Salicylic Acid Pharma Grade plays a crucial role in numerous industrial applications.
Salicylic Acid Pharma Grade serves as an essential ingredient in various chemical processes, including the production of dyes, coatings, and adhesives.
Its impressive physicochemical properties, such as high solubility and boiling point, make Salicylic Acid Pharma Grade a reliable component for a wide range of industries.


Salicylic Acid Pharma Grade may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrofluorometric technique.
Salicylic Acid Pharma Grade is widely used in food industry for producing dyes and artificial scents.


Salicylic Acid Pharma Grade also shows therapeutic potential in protecting the skin from sun damage and hence finds applications in cosmetics and medicine.
As an environmentally conscious choice, Salicylic Acid Pharma Grade ensures optimal compatibility with nature.
Salicylic Acid Pharma Grade is biodegradable and has negligible ecotoxicity, making it a safe option for both users and the environment.


By choosing Salicylic Acid Pharma Grade, you are making a sustainable choice without compromising on quality or effectiveness.
Salicylic Acid Pharma Grade is an important material in pharmaceutical industry, obtained via the decomposition of acetylsalicylic acid.
Salicylic Acid Pharma Grade can be used as a fluorescent indicator


Salicylic Acid Pharma Grade is widely used in the rubber industry and can be used as an ultraviolet absorber and foaming agent
Salicylic Acid Pharma Grade is also widely used in tungsten ion preservatives
Salicylic Acid Pharma Grade can be used as an additive in the electrolyte


Application of Salicylic Acid Pharma Grade in cosmetics: Since Salicylic Acid Pharma Grade has a certain irritant, it can be used as an additive in toilet water prickly heat powder in the cosmetics industry.
In addition, Salicylic Acid Pharma Grade also has a sterilizing and disinfecting effect, which can be used to reduce swelling and itching.


Salicylic Acid Pharma Grade is used Semiconductors, nanoparticles, photoresists, lubricating oils, UV absorbers, adhesive, leather, cleaner, hair dye, soaps, cosmetics, pain medication, analgesics, antibacterial agent, treatment of dandruff, hyperpigmented skin, tinea pedis, onychomycosis, osteoporosis, beriberi, fungicidal skin disease, autoimmune disease.


Salicylic Acid Pharma Grade is widely used in organic synthesis and functions as a plant hormone and is known for its ability to ease aches and pains and reduce fevers.
Salicylic Acid Pharma Grade is derived from the metabolism of salicin.


Salicylic Acid Pharma Grade and its derivatives are used as constituents of some rubefacient products.
Salicylic Acid Pharma Grade is a keratolytic agent (mostly used in creams, ointments and shampoos).
Chemical synthesis of Salicylic Acid Pharma Grade: starting material for the synthesis of active pharmaceutical ingredients, antiseptic agents, fragrance chemicals, etc.


Pharmaceutical applications: Salicylic Acid Pharma Grade is a keratolytic agent (mostly used in creams, ointments and shampoos)
Chemical synthesis: starting material for the synthesis of active pharmaceutical ingredients, antiseptic agents, fragrance chemicals, etc.
Food industry: Salicylic Acid Pharma Grade is used preservative.


Personal care applications: Salicylic Acid Pharma Grade is used in cosmetics.
Delivers Salicylic Acid Pharma Grade that causes cells of the epidermis to shed more readily, opening clogged pores, and neutralizing the bacteria within.
Salicylic Acid Pharma Grade is Preservative-free.


Ready to formulate a solution of Salicylic Acid Pharma Grade.
Salicylic Acid Pharma Grade is ideal for soap bars (alkaline), basis, powder anti-acne, and other applications.
Salicylic Acid Pharma Grade is stable form of ready to use.


Technology to enhance acids for use in high pH environments
Salicylic Acid Pharma Grade has enhanced efficacy.
Use of Salicylic Acid Pharma Grade in medicine: sodium salicylate, aspirin, analgesic granules, etc.
The use of Salicylic Acid Pharma Grade in industry: disinfectants and preservatives, rubber retarders.


-Medicine uses of Salicylic Acid Pharma Grade:
Salicylic Acid Pharma Grade as a medication is commonly used to remove the outer layer of the skin.
As such, Salicylic Acid Pharma Grade is used to treat warts, psoriasis, acne vulgaris, ringworm, dandruff, and ichthyosis.
Similar to other hydroxy acids, Salicylic Acid Pharma Grade is an ingredient in many skincare products for the treatment of seborrhoeic dermatitis, acne, psoriasis, calluses, corns, keratosis pilaris, acanthosis nigricans, ichthyosis, and warts.



PHARMACODYNAMICS USES OF SALICYLIC ACID PHARMA GRADE:
Salicylic Acid Pharma Grade treats acne by causing skin cells to slough off more readily, preventing pores from clogging up.
This effect on skin cells also makes Salicylic Acid Pharma Grade an active ingredient in several shampoos meant to treat dandruff.

Use of straight Salicylic Acid Pharma Grade may cause hyperpigmentation on unpretreated skin for those with darker skin types (Fitzpatrick phototypes IV, V, VI), as well as with the lack of use of a broad spectrum sunblock.

Subsalicylate in combination with bismuth form the popular stomach relief aid known commonly as Pepto-Bismol.
When combined the two key ingredients help control diarrhea, nausea, heartburn, and even gas.
Salicylic Acid Pharma Grade is also very mildly anti-biotic.



KEY FEATURES OF SALICYLIC ACID PHARMA GRADE:
*Pharmaceutical-Grade: Meeting Stringent Quality Standards
*Broad-Spectrum Uses: Pharmaceutical, Cosmetic, and Industrial Fields
*Unparalleled Purity and Potency
*Impressive Physicochemical Properties, Including High Solubility and Boiling Point
*Antiseptic, Anti-Inflammatory, and Analgesic Properties
*Environmentally Compatible: Biodegradable and Negligible *Ecotoxicity



PRODUCTION AND CHEMICAL REACTIONS OF SALICYLIC ACID PHARMA GRADE:
BIOSYNTHESIS:
Salicylic Acid Pharma Grade is biosynthesized from the amino acid phenylalanine.
In Arabidopsis thaliana, Salicylic Acid Pharma Grade can be synthesized via a phenylalanine-independent pathway.



CHEMICAL SYNTHESIS OF SALICYLIC ACID PHARMA GRADE:
Commercial vendors prepare sodium salicylate by treating sodium phenolate (the sodium salt of phenol) with carbon dioxide at high pressure (100 atm) and high temperature (115 °C) – a method known as the Kolbe-Schmitt reaction.

Acidifying the product with sulfuric acid gives Salicylic Acid Pharma Grade:
At the laboratory scale, Salicylic Acid Pharma Grade can also be prepared by the hydrolysis of aspirin (acetylsalicylic acid) or methyl salicylate (oil of wintergreen) with a strong acid or base; these reactions reverse those chemicals' commercial syntheses.



MECHANISM OF ACTION OF SALICYLIC ACID PHARMA GRADE:
Salicylic Acid Pharma Grade modulates COX-1 enzymatic activity to decrease the formation of pro-inflammatory prostaglandins.
Salicylate may competitively inhibit prostaglandin formation.
Salicylate's antirheumatic (nonsteroidal anti-inflammatory) actions are a result of its analgesic and anti-inflammatory mechanisms.



REACTIONS OF SALICYLIC ACID PHARMA GRADE:
Upon heating, Salicylic Acid Pharma Grade converts to phenyl salicylate:
2 HOC6H4CO2H → C6H5O2C6H4OH + CO2 + H2O
Further heating gives xanthone.

Salicylic Acid Pharma Grade as its conjugate base is a chelating agent, with an affinity for iron(III).
Salicylic Acid Pharma Grade slowly degrades to phenol and carbon dioxide at 200–230 °C:
C6H4OH(CO2H) → C6H5OH + CO2



FUNCTION OF SALICYLIC ACID PHARMA GRADE:
Salicylic Acid Pharma Grade is known for its ability to ease aches and pains and reduce fevers.
These medicinal properties, particularly fever relief, have been known since ancient times, and Salicylic Acid Pharma Grade is used as an ant-inflammatory drug.

As with other beta hydroxy acids, Salicylic Acid Pharma Grade is a key ingredient in many skin-care products for the treatment of seborrhoeic dermatitis, acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
Salicylic Acid Pharma Grade is one kind of very good functional ingredients.

First, Salicylic Acid Pharma Grade can effectively restrain many bacteriums such as Ureate staphylococcus and Acne propanoic acid bacillus.
Second, Salicylic Acid Pharma Grade can control the sebum overmuch secretion and effectively restrain acne.
Third, Salicylic Acid Pharma Grade can better transport the active ingredient to skin and reduce skin wrinkle.



DIETARY SOURCES, SALICYLIC ACID PHARMA GRADE:
Salicylic Acid Pharma Grade occurs in plants as free salicylic acid and its carboxylated esters and phenolic glycosides.
Several studies suggest that humans metabolize Salicylic Acid Pharma Grade in measurable quantities from these plants.
High-salicylate beverages and foods include beer, coffee, tea, numerous fruits and vegetables, sweet potato, nuts, and olive oil.

Meat, poultry, fish, eggs, dairy products, sugar, breads and cereals have low salicylate content.
Some people with sensitivity to dietary salicylates may have symptoms of allergic reaction, such as bronchial asthma, rhinitis, gastrointestinal disorders, or diarrhea, so may need to adopt a low-salicylate diet.



PLANT HORMONE, SALICYLIC ACID PHARMA GRADE:
Salicylic Acid Pharma Grade is a phenolic phytohormone, and is found in plants with roles in plant growth and development, photosynthesis, transpiration, and ion uptake and transport.
Salicylic Acid Pharma Grade is involved in endogenous signaling, mediating plant defense against pathogens.

Salicylic Acid Pharma Grade plays a role in the resistance to pathogens (i.e. systemic acquired resistance) by inducing the production of pathogenesis-related proteins and other defensive metabolites.

Salicylic Acid Pharma Grade's defense signaling role is most clearly demonstrated by experiments which do away with it: Delaney et al. 1994, Gaffney et al. 1993, Lawton et al. 1995, and Vernooij et al. 1994 each use Nicotiana tabacum or Arabidopsis expressing nahG, for salicylate hydroxylase.

Pathogen inoculation did not produce the customarily high Salicylic Acid Pharma Grade levels, SAR was not produced, and no PR genes were expressed in systemic leaves.
Indeed, the subjects were more susceptible to virulent – and even normally avirulent – pathogens.

Exogenously, it can aid plant development via enhanced seed germination, bud flowering, and fruit ripening, though too high of a concentration of Salicylic Acid Pharma Grade can negatively regulate these developmental processes.

The volatile methyl ester of Salicylic Acid Pharma Grade, methyl salicylate, can also diffuse through the air, facilitating plant-plant communication.
Methyl salicylate is taken up by the stomata of the nearby plant, where it can induce an immune response after being converted back to Salicylic Acid Pharma Grade.



HISTORY OF SALICYLIC ACID PHARMA GRADE:
Willow has long been used for medicinal purposes.
Dioscorides, whose writings were highly influential for more than 1,500 years, used 'Itea' (which was possibly a species of willow) as a treatment for 'painful intestinal obstructions,' birth control, for 'those who spit blood,' to remove calluses and corns and, externally, as a 'warm pack for gout.'

William Turner, in 1597, repeated this, saying that willow bark, 'being burnt to ashes, and steeped in vinegar, takes away corns and other like risings in the feet and toes.'
Some of these cures may describe the action of Salicylic Acid Pharma Grade, which can be derived from the salicin present in willow.

Salicylic Acid Pharma Grade is, however, a modern myth that Hippocrates used willow as a painkiller.
Salicylic Acid Pharma Grade was used in Europe and China to treat these conditions.
This remedy is mentioned in texts from Ancient Egypt, Sumer, and Assyria.

The Cherokee and other Native Americans use an infusion of the bark for fever and other medicinal purposes.
In 2014, archaeologists identified traces of Salicylic Acid Pharma Grade on seventh-century pottery fragments found in east-central Colorado.
The Reverend Edward Stone, a vicar from Chipping Norton, Oxfordshire, England, reported in 1763 that the bark of the willow was effective in reducing a fever.

An extract of willow bark, called salicin, after the Latin name for the white willow (Salix alba), was isolated and named by German chemist Johann Andreas Buchner in 1828.
A larger amount of the substance was isolated in 1829 by Henri Leroux, a French pharmacist.

Raffaele Piria, an Italian chemist, was able to convert the substance into a sugar and a second component, which on oxidation becomes Salicylic Acid Pharma Grade.
Salicylic Acid Pharma Grade was also isolated from the herb meadowsweet (Filipendula ulmaria, formerly classified as Spiraea ulmaria) by German researchers in 1839.

Their extract caused digestive problems such as gastric irritation, bleeding, diarrhea, and even death when consumed in high doses.
In 1874 the Scottish physician Thomas MacLagan experimented with salicin as a treatment for acute rheumatism, with considerable success, as he reported in The Lancet in 1876.

Meanwhile, German scientists tried sodium salicylate with less success and more severe side effects.
In 1979, salicylates were found to be involved in induced defenses of tobacco against tobacco mosaic virus.
In 1987, Salicylic Acid Pharma Grade was identified as the long-sought signal that causes thermogenic plants, such as the voodoo lily, Sauromatum guttatum, to produce heat.



HOW THE TECHNOLOGY HELPS YOU, SALICYLIC ACID PHARMA GRADE:
Salicylic Acid Pharma Grade is double encapsulated.
Salicylic Acid Pharma Grade is contained in sub-micron spheres (0.1-2 microns in diameter), then re-encapsulated into larger microspheres.



PHYSICAL and CHEMICAL PROPERTIES of SALICYLIC ACID PHARMA GRADE:
Formula : C7H6O3
Molecular weight : 138,12 g/mol
CAS-No. : 69-72-7
EC-No. : 200-712-3
Physical state: powdercrystalline
Color: white
Odor: odorless
Melting point/freezing point:
Melting point/range: 158 - 160 °C
Initial boiling point and boiling range: 211 °C at 27 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Lower explosion limit: 1,1 %(V)
Flash point 157 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 2,4 at 20 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water:

log Pow: 2,25 at 25 °C - Bioaccumulation is not expected.
Vapor pressure: 1 hPa at 114 °C
Density: 1,44 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Chemical Name : 2 – Hydroxybenzoic Acid
Molecular Formula : C7H6O3
Molecular Weight : 138.1
Description : White / colourless, crystalline powder / acicular crystals
CAS No. : 69-72-7
CAS: 69-72-7
MF: C7H6O3
MW: 138.12
EINECS: 200-712-3
Mol File: 69-72-7.mol
Salicylic acid: Chemical Properties
Melting point: 158-161 °C(lit.)
Boiling point: 211 °C(lit.)
density: 1.44

vapor density: 4.8 (vs air)
vapor pressure: 1 mm Hg ( 114 °C)
refractive index: 1,565
FEMA: 3985 | 2-HYDROXYBENZOIC ACID
Fp: 157 °C
storage temp.: 2-8°C
solubility: ethanol: 1 M at 20 °C, clear, colorless
pka: 2.98(at 25℃)
form: Solid
color: White to off-white
PH Range: Non0 uorescence (2.5) to dark blue 0 uorescence (4.0)
Odor: at 100.00 %. faint phenolic nutty
PH: 3.21(1 mM solution);2.57(10 mM solution);2.02(100 mM solution);
Odor Type: nutty
Water Solubility: 1.8 g/L (20 ºC)
Sensitive: Light Sensitive
λmax: 210nm, 234nm, 303nm
Merck: 148,332
JECFA Number: 958
Sublimation: 70 ºC
BRN: 774890
Stability: Stable.
InChIKey: YGSDEFSMJLZEOE-UHFFFAOYSA-N

LogP: 2.01
CAS DataBase Reference: 69-72-7(CAS DataBase Reference)
NIST Chemistry Reference: Benzoic acid, 2-hydroxy-(69-72-7)
EPA Substance Registry System: Salicylic acid (69-72-7)
IUPAC Name: 2-hydroxybenzoic acid
Molecular Weight: 138.12
Molecular Formula: C7H6O3
Canonical SMILES: C1=CC=C(C(=C1)C(=O)O)O
InChI: InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChIKey: YGSDEFSMJLZEOE-UHFFFAOYSA-N
Boiling Point: 211 ℃ (20 mmHg)
Melting Point: 154-156 ℃
Flash Point: 157ºC
Purity: > 98 %
Density: 1.44 g/cm3
Solubility: Solubility (weight percent):
carbon tetrachloride 0.262 (25 °C);
benzene 0.775 (25 °C); propanol 27.36 (21 °C);
absolute ethanol 34.87 (21 °C); acetone 396 (23 °C)
Appearance: White poder
Storage: Store at RT.
EINECS: 200-712-3
Hazard Codes: Xn

HS Code: 2918211000
Log P: 1.09040
MDL: MFCD00002439
pH: pH of saturated solution: 2.4
PSA: 57.53
Quality Standard: Enterprise Standard
Refractive Index: 1.565
Risk Statements: R22; R36/37/38; R41
RTECS: VO0525000
Safety Statements: S26-S37/39
Stability: Stable.
Vapor Density: 4.8
Vapor Pressure: 1 mm Hg ( 114 °C)
Odour: Almost Odourless.
Melting Range: 158.5°C to 161.0°C.
Appearance of Solution/
Clarity & Colour of Solution: Passes test as per B.P./I.P.
Heavy Metals: 20 ppm (max)
Sulphated Ash/Residue on Ignition: 0.1% w/w (I.P./B.P.Limit) / 0.05% w/w (U.S.P. Limit)
Chloride: 125 ppm (max.) I.P./100 ppm (max.) B.P.
Sulphate: 0.02% (max.) I.P./140 ppm U.S.P.
Related Substance: Complies with the B.P. test.
Loss of Drying: 0.5% (max.) B.P.

Iron: 2 ppm (max.) I.P.
Molecular Weight: 138.12 g/mol
XLogP3: 2.3
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 1
Exact Mass: 138.031694049 g/mol
Monoisotopic Mass: 138.031694049 g/mol
Topological Polar Surface Area: 57.5Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 133
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
CAS number: 69-72-7
EC number: 200-712-3
Hill Formula: C₇H₆O₃
Chemical formula: HOC₆H₄COOH

Molar Mass: 138.12 g/mol
HS Code: 2918 21 10
Boiling point: 211 °C (1013 hPa)
Density: 1.44 g/cm3 (20 °C)
Flash point: 157 °C
Ignition temperature: 500 °C
Melting Point: 158 - 160 °C
pH value: 2.4 (H₂O, 20 °C) (saturated solution)
Vapor pressure: 1 hPa (114 °C)
Bulk density: 400 - 500 kg/m3
Solubility: 2 g/l
Chemical formula: C7H6O3
Molar mass: 138.122 g/mol
Appearance: Colorless to white crystals
Odor: Odorless
Density: 1.443 g/cm3 (20 °C)
Melting point: 158.6 °C (317.5 °F; 431.8 K)
Boiling point: 211 °C (412 °F; 484 K) at 20 mmHg
Sublimation conditions: Sublimes at 76 °C
Solubility in water:
1.24 g/L (0 °C)
2.48 g/L (25 °C)
4.14 g/L (40 °C)
17.41 g/L (75 °C)
77.79 g/L (100 °C)

Solubility: Soluble in ether, CCl4, benzene, propanol,
acetone, ethanol, oil of turpentine, toluene
Solubility in benzene:
0.46 g/100 g (11.7 °C)
0.775 g/100 g (25 °C)
0.991 g/100 g (30.5 °C)
2.38 g/100 g (49.4 °C)
4.4 g/100 g (64.2 °C)
Solubility in chloroform:
2.22 g/100 mL (25 °C)
2.31 g/100 mL (30.5 °C)
Solubility in methanol:
40.67 g/100 g (−3 °C)
62.48 g/100 g (21 °C)
Solubility in olive oil: 2.43 g/100 g (23 °C)
Solubility in acetone: 39.6 g/100 g (23 °C)
log P: 2.26
Vapor pressure: 10.93 mPa
Acidity (pKa):
2.97 (25 °C)
13.82 (20 °C)
UV-vis (λmax): 210 nm, 234 nm, 303 nm (4 mg/dL in ethanol)
Magnetic susceptibility (χ): −72.23·10−6 cm3/mol
Refractive index (nD): 1.565 (20 °C)
Dipole moment: 2.65 D
Thermochemistry:
Std enthalpy of formation (ΔfH⦵298): −589.9 kJ/mol
Std enthalpy of combustion (ΔcH⦵298): -3.025 MJ/mol



FIRST AID MEASURES of SALICYLIC ACID PHARMA GRADE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact: rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of SALICYLIC ACID PHARMA GRADE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of SALICYLIC ACID PHARMA GRADE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of SALICYLIC ACID PHARMA GRADE:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of SALICYLIC ACID PHARMA GRADE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Store at Room Temperature.
Light sensitive



STABILITY and REACTIVITY of SALICYLIC ACID PHARMA GRADE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available



SYNONYMS:
2-Hydroxybenzoic acid
2-HYDROXYBENZOIC ACID
ACIDUM SALICYLICUM
ACETYLSALISYLIC ACID IMP C
ACETYLSALICYLIC ACID IMPURITY C
FEMA 3985
SALICYCLIC ACID
SALICYLIC ACID
RETARDER TSA
salicylic acid
2-Hydroxybenzoic acid
69-72-7
o-hydroxybenzoic acid
2-Carboxyphenol
o-Carboxyphenol
Rutranex
Salonil
Retarder W
Duoplant
Keralyt
Psoriacid-S-stift
Freezone
Saligel
Ionil
Salicylic acid soap
Stri-Dex
Verrugon
Salicylic acid collodion
Benzoic acid, 2-hydroxy-
2-Hydroxybenzenecarboxylic acid
Phenol-2-carboxylic acid
Orthohydroxybenzoic acid
Acido salicilico
Kyselina salicylova
2-hydroxy-benzoic acid
CCRIS 6714
HSDB 672
AI3-02407
CHEBI:16914
BRN 0774890
NSC-180
UNII-O414PZ4LPZ
EINECS 200-712-3
O414PZ4LPZ
MFCD00002439
DTXSID7026368
FEMA NO. 3985
CHEMBL424
Salicylic acid [USP:JAN]
MLS000069653
DTXCID206368
NSC180
K 537
EC 200-712-3
29656-58-4
SMR000059163
Acid, Salicylic
ortho-Hydroxybenzoic Acid
Salicylic acid (USP:JAN)
SALICYLIC ACID (USP)
SALICYLIC ACID [USP]
o Hydroxybenzoic Acid
SALICYLIC ACID (MART.)
SALICYLIC ACID [MART.]
SALICYLIC ACID (USP-RS)
Salicylic acid [USAN:JAN]
SALICYLIC ACID [USP-RS]
2 Hydroxybenzoic Acid
Acid, o-Hydroxybenzoic
Acid, 2-Hydroxybenzoic
ortho Hydroxybenzoic Acid
SALICYLIC ACID (EP IMPURITY)
SALICYLIC ACID [EP IMPURITY]
SALICYLIC ACID (EP MONOGRAPH)
SALICYLIC ACID [EP MONOGRAPH]
Acid, ortho-Hydroxybenzoic
SALICYLIC ACID (USP MONOGRAPH)
SALICYLIC ACID [USP MONOGRAPH]
CAS-69-72-7
LAMIVUDINE IMPURITY C (EP IMPURITY)
LAMIVUDINE IMPURITY C [EP IMPURITY]
MESALAZINE IMPURITY H (EP IMPURITY)
MESALAZINE IMPURITY H [EP IMPURITY]
NSC629474
phenol derivative, 7
Salicylic acid (TN)
SULFASALAZINE IMPURITY H (EP IMPURITY)
SULFASALAZINE IMPURITY H [EP IMPURITY]
ACETYLSALICYLIC ACID IMPURITY C (EP IMPURITY)
ACETYLSALICYLIC ACID IMPURITY C [EP IMPURITY]
Salicylic Acide
Salicylic Aclid
Salicyllic Acid
Salicylic Acid (1%)
Salicylic Acid 0.5%
Salicylic Acid 1.5%
Salicylic Acid 2.0%
Salicylic Acid 3.0%
Salicylic Acid 5.9%
SCHEMBL1967
SALICYLIC ACID [MI]
Oprea1_040343
KBioSS_001428
BIDD:ER0602
NCGC00159447-01
NCGC00159447-02
NCGC00159447-04
NCGC00159447-06
NCGC00257065-01
NCGC00259022-01
FT-0645123
FT-0674502
FT-0674503
H0206
H1342
Salicylic Acid Technical Grade
Unichem Salac
2-Hydroxybenzoic acid
2-Carboxyphenol
Salicylic acid


SALICYLIC ACID POWDER
DESCRIPTION:
Salicylic Acid Powder ≥99.5% USP Grade is a cosmetic-grade product that, in creams and solutions, can be used topically for treating several skin conditions that involve overgrowth of cells, scaling, calluses, warts, dandruff, etc.
Salicylic Acid Powder is also effective for acne treatment and penetrates the skin to remove damaged cells clogging pores.

CAS Number, 69-72-7

SYNONYMS OF SALICYLIC ACID POWDER:
salicylic acid, o-hydroxybenzoic acid, 2-carboxyphenol, o-carboxyphenol, rutranex, salonil, retarder w, keralyt, duoplant, freezone

Salicylic Acid Powder ≥99.5% USP Grade is in compliance with the United States Pharmacopeia (USP) making it suitable for skincare products, drugs, and similar applications such as the manufacture of soap, shampoo, and cosmetics.
The sodium salt of acid is added to mouthwashes and toothpastes to fight bacteria build up.

Salicylic acid (from Latin salix, willow tree) is a lipophilic monohydroxybenzoic acid, a type of phenolic acid, and a beta hydroxy acid (BHA).
Salicylic Acid Powder has the formula C7H6O3.
Salicylic acid powder is a versatile product used in various industries, including pharmaceuticals, cosmetics, and agriculture.

Salicylic Acid Powder is commonly used as an active ingredient in acne treatments, dandruff shampoos, and wart removers due to its exfoliating and anti-inflammatory properties.
Additionally, salicylic acid powder is used in the production of aspirin and as a plant growth regulator.
Its ability to penetrate the skin and unclog pores makes Salicylic Acid Powder a popular ingredient in skincare products.


100% pure, natural, and undiluted salicylic acid contains no adulterants.
Since the acid is concentrated in nature, please do not use the product without dilution.
Salicylic acid works by loosening and breaking apart the outermost dead cells.
And Salicylic Acid Powder encourages the exfoliation of the outermost dead skin cells and unclogging of pores.


Salicylic acid is a beta-hydroxy acid, or BHA, and is a powerful and effective exfoliant widely used for face peels and in products for teenage or oily skin.
Please note that it must not be used above 2% in any cosmetic formulas.

Because the structure of salicylic acid makes it alcohol- and oil-soluble, it's able to connect with the skin more efficiently than water-soluble-only products and is a wonderful ingredient in products targeted at pores.

Salicylic Acid Powder can often lower the pH of your final product, so be sure to test the pH to ensure it is 3.5 or above.
Salicylic Acid Powder is prepared by the carboxylation of sodium phenate and has a long shelf life when kept cool and dry.


Salicylic Acid Powder is a white colorless crystalline powder that is mainly used for anti-acne products.
Salicylic Acid Powder also can serve as an anti-dandruff agent, denaturant, exfoliant, hair conditioning agent, preservative, and skin conditioning agent with keratolytic properties.

Salicylic Acid Powder can be used in a wide range of personal care and cosmetic products in the formulation of moisturizers, skin cleansing products, shampoos, as well as skin care, hair care, products designed to remove corns, calluses and warts, suntan and sunscreen products.

Salicylic acid is a beta hydroxy acid.
It’s well-known for reducing acne by exfoliating the skin and keeping pores clear.
Salicylic Acid Powder works best for mild acne (blackheads and whiteheads). It can also help prevent future breakouts.


Salicylic Acid Powder is difficult to dissolve in water easily soluble in ethanol, ether, acetone and other solvents, but adding solubilizer can help it to dissolve in water system.
Salicylic acid is a small molecule acid with strong permeability.
Salicylic Acid Powder has lipophilic and exfoliating effects, and has a good therapeutic effect on melasma, post-inflammatory pigmentation, rough skin and photoaging symptoms.

Salicylic Acid Powder also can remove dead cells, balance excessive keratinization, and make the face smooth and elastic.
Thus Salicylic Acid Powder can be recommended for keratinization abnormalities, whitening, anti-acne, anti-aging/photoaging and other products.




USES AND APPLICATIONS OF SALICYLIC ACID POWDER:
Salicylic Acid Powder is used in Treatment for various minor skin conditions
Salicylic Acid Powder is used as Food preservative
Salicylic Acid Powder is used as Analytic reagent


Salicylic Acid Powder is used in skin-care products for treating acne and pimple-prone skin, as well as various skin problems, such as warts, corns, calluses and psoriasis.
Salicylic Acid Powder is also commonly used in dandruff shampoos.
This is because of the acid's ability to cause skin cells to slough off, facilitating new skin cell growth, unclogging pores and removing overgrown skin cells.


Salicylic Acid Powder is pure and contains no adulterants.
Salicylic Acid Powder is used in skin enhancement cosmetics and also prevents dandruff.
Salicylic Acid Powder also helps cure skin irritation, redness, acne breakouts, and other skin-related problems.
Salicylic Acid Powder is used in soap, gel, lotion, cleansers, shampoo, masks, serums, moisturizers, face wash, and face pads.





USAGE INSTRUCTIONS OF SALICYLIC ACID POWDER:
A maximum level of 2% is permitted in adult formulations that are to be left on the skin and 3% as a max for rinse off products.
The ingredient is not to be used in products targeting children under the age of three except as part of the preservative or shampoo.

Formulating Tips:
Salicylic acid can be very tricky to add into an emulsion formulation (A cream or lotion) as it is not that soluble in water or oils.
One option is to neutralise it into sodium salicylate by reacting it with sodium bicarbonate.
This will fizz in water until the reaction is complete, the salt is just as effective for the skin as the acid but has less solubility issues.

Otherwise you can try dispersing it beforehand into a suitable solvent.
Propylene Glycol and glycerine can help as can adding what is known as a hydrotrope (to improve solubility).
Examples of this are urea and/ or Sodium Citrate.

Salicylic Acid must be used with caution because salicylic acid is in the same family as aspirin and will be absorbed into the skin and sometimes can burn the skin!
Dandruff is a scalp condition which produces a dry, flaking scaling scalp.
Most people with dandruff typically will treat their head with shampoos containing selenium sulfide, salicylic acid or coal tars.
Corticosteroids may also be applied to help limit the dandruff.




BENEFITS OF SALICYLIC ACID POWDER:
Salicylic Acid Powder helps exfoliate unwanted rough and dead skin.
Pure Salicylic Acid acts as a great DIY ingredient for the preparation of several skincare products.
Salicylic acid is used in shampoo to remove dandruff since it may cause skin cells to slough off; Salicylic Acid Powder facilitates new skin cells.

Salicylic acid may help manage several skin problems.
Salicylic Acid Powder is best not to apply on broken, red, swollen and irritated skin.

Salicylic Acid Powder Helps in the treatment of acne and psoriasis
Salicylic Acid Powder Reduces redness and blockage in skin
Salicylic Acid Powder Prevents blackheads and whiteheads
Salicylic Acid Powder Helps in preventing skin blemishes



Salicylic acid powder is beneficial in the treatment of skin issues such as acne and redness
Salicylic Acid Powder is recommended in conditions such as ichthyoses, psoriasis and calluses
Salicylic Acid Powder helps in reducing acne by dissolving skin debris so that it can fall off
Salicylic Acid Powder exfoliates the skin which makes it look fresh and rejuvenated



CHEMICAL AND PHYSICAL PROPERTIES OF SALICYLIC ACID POWDER:
CAS Number, 69-72-7
Molecular Formula, C7H6O3
Formula Weight, 138.12
Synonyms, salicylic acid, o-hydroxybenzoic acid, 2-carboxyphenol, o-carboxyphenol, rutranex, salonil, retarder w, keralyt, duoplant, freezone
PubChem CID, 338
Grade, USP Grade
Percent Purity, 99.5-101.0%
Chemical Name or Material, Salicylic Acid

Salicylic Acid Powder ≥99.5% USP Grade Specifications:
Assay, 99.5-101.0%
Melting Range, 158°-161°C
Loss on Drying, 0.5% max
Residue on Ignition, 0.05 max%
Chloride (Cl), 0.0100% max
Sulfate (SO4), 0.0200% max
Heavy Metals (as Pb), 0.0200% max
Coloration of ethanolic solution, haz, 10 max
Residual solvents, None
4-hydroxybenzoic acid, %, 0.10 max
4-hydroxyisophthalic acid, %, 0.05 max
Phenol, %, 0.01 max
Total impurities, %, 0.20 max
IR spectrum, To Pass Test
Location of main assay peak, To Pass Test
Clarity of ethanolic solution, To Pass Test
No other relat. subst. >0.05%, To Pass Test
Category: Additive
Ingredient Function: Exfolliant
Used in: Cleansers, Scrubs, Lotions
Solubility: Soluble in alcohol & glycols, but best when both are used & heated up to 40-45 oC (104F - 115F)
Appearance: White Powder
Odor: Slightly phenolic (sweet and tarry)
INCI: Salicylic Acid Powder
Purity: 99%
Physical Form: White Crystalline Powder
Melting Point: 130-132°C
Applications: Topical
Usage Rate: Up to 2% (start at a .5% or lower)
Solubility: Alcohol and/or Propylene Glycols (Zemea recommended), Oil
CAS# 69-72-7
Classification: FCC/USP
Origin: USA
Odor: Odorless
pH: Acidity (pKa) 2.97
Assay USP Dry Basis, ≥99.2%-102%
Appearance (Color), Fine White Powder
Infrared Spectrum , Conforms to Structure
Melting Point, 158.8C
Loss on Drying , <0.1%
Sulfates, <0.0130%
Heavy Metals, <0.0010%
Chlorides , <0.0100%
Total Impurities, <0.10%
CAS, 69-72-7
Molecular Formula, C7H6O3
InChI Key, YGSDEFSMJLZEOE-UHFFFAOYSA-N
IUPAC Name, 2-hydroxybenzoic acid
Percent Purity, 98 to 102%
Quantity, 2.5 kg
Loss on Drying, 0.005
CAS Max %, 1
MDL Number, MFCD00002439
SMILES, OC(=O)C1=CC=CC=C1O
Molecular Weight (g/mol), 138.12
Grade, USP
Ignition Residue, 0.0005
Molecular Weight (g/mol), 138.12
InChI Key, YGSDEFSMJLZEOE-UHFFFAOYSA-N
SMILES, OC(=O)C1=CC=CC=C1O




SAFETY INFORMATION ABOUT SALICYLIC ACID POWDER:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product
Salicylate de benzyle
BUTYL SALICYLAT; ,butyl 2-hydroxybenzoate; N° CAS : 2052-14-4, Nom INCI : BUTYL SALICYLATE, Nom chimique : Butyl 2-Hydroxybenzoate, N° EINECS/ELINCS : 218-142-9. Agent parfumant: : Utilisé pour le parfum et les matières premières aromatiques. n-Butyl salicylate; 2052-14-4 [RN]; 218-142-9 [EINECS]; Benzoic acid, 2-hydroxy-, butyl ester [ACD/Index Name];Benzoic acid, hydroxy-, butyl ester; Butyl hydroxybenzoate; Butyl salicylate; Butylsalicylat [German] ; n-Butyl hydroxybenzoate; Salicylate de butyle [French] ; Salicylic acid, n-butyl ester [2052-14-4] 1322-01-6 [RN] '2052-14-4 2-hydroxybenzoic acid butyl ester 2-Hydroxy-benzoic acid, butyl ester 4-10-00-00153 [Beilstein] Brunol Butyl (2-hydroxyphenyl)formate butyl 2-hydroxybenzoate Butyl o-hydroxybenzoate BUTYL ORTHO HYDROXY BENZOATE butyl salicylate, Butylsalicylate EINECS 218-142-9 FEMA 3650 n-Butyl o-hydroxybenzoate Nefolia Salicylic acid N-butyl ester Salicylic acid, butyl ester
Salicylate de butyle ( BUTYL SALICYLATE)
METHYL SALICYLATE, N° CAS : 119-36-8 - Salicylate de méthyle, Nom INCI : METHYL SALICYLATE, Nom chimique : Methyl salicylate, N° EINECS/ELINCS : 204-317-7. Dénaturant : Rend les cosmétiques désagréables. Principalement ajouté aux cosmétiques contenant de l'alcool éthylique. Agent apaisant : Aide à alléger l'inconfort de la peau ou du cuir chevelu. Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques. 2-(Methoxycarbonyl)phenol, Methyl-2-hydroxybenzoate, Methyl salicylate, o-Hydroxybenzoic acid, methyl ester, salicylate de methyle, salicylic acid, methyl ester, Wintergreen oil. Noms français : (METHOXYCARBONYL)-2 PHENOL; 2-(METHOXYCARBONYL)PHENOL; 2-HYDROXYBENZOIC ACID METHYL ESTER; BENZOIC ACID, 2-HYDROXY-, METHYL ESTER; ESSENCE DE THE DE BOIS; HYDROXYBENZOATE DE METHYLE (ORTHO-); METHYL O-HYDROXYBENZOATE; O-HYDROXYBENZOIC ACID, METHYL ESTER; Salicylate de méthyle; SALICYLIC ACID, METHYL ESTER. Noms anglais : BETULA LENTA; BETULA OIL; GAULTHERIA OIL; Methyl salicylate; NATURAL WINTERGREEN OIL OIL OF WINTERGREEN; OILS, WINTERGREEN; SYNTHETIC WINTERGREEN OIL; TEABERRY OIL; WINTERGREEN OIL, SYNTHETIC. Utilisation et sources d'émission: Fabrication de parfums, agent de saveur
salicylate de methyle  (METHYL SALICYLATE)
1-Hexyl salicylate; Salicylate d'hexyle; HEXYL SALICYLATE, N° CAS : 6259-76-3, Nom INCI : HEXYL SALICYLATE, Nom chimique : Benzoic Acid, 2-hydroxy-, 2-hexyl ester, N° EINECS/ELINCS : 228-408-6, Ses fonctions (INCI): Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit. Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques. Noms français : Salicylate d'hexyle. Noms anglais : 1-Hexyl salicylate; BENZOIC ACID, 2-HYDROXY-, HEXYL ESTER; Hexyl salicylate; N-HEXYL SALICYLATE; Salicylic acid, hexyl ester. Utilisation et sources d'émission: Parfumerie. 228-408-6 [EINECS]; 2453103; 6259-76-3 [RN]; Benzoic acid, 2-hydroxy-, hexyl ester [ACD/Index Name]; DH2207000; hexyl 2-hydroxybenzoate; hexyl salicylate [ACD/IUPAC Name]; Hexylsalicylat [German] [ACD/IUPAC Name]; MFCD00036487 [MDL number]İ Salicylate d'hexyle [French] [ACD/IUPAC Name]; [6259-76-3]; 1-Hexyl salicylate; 2-hexoxybenzoic acid; 2-Hydroxybenzoic acid hexyl ester; '6259-76-3; 6259-79-6 [RN]; Benzoic acid, hydroxy-, hexyl esterİ EINECS 228-408-6; HEXYL SALICYLATE; Hexyl 2-hydroxybenzoic acid; Hexyl salicylic acid Hexylsalicylat; Hexylsalicylate; N-HEXYL 2-HYDROXYBENZOATE; n-Hexyl salicylate; n-hexyl salicylate 95%; OC1=C(C=CC=C1)C(OCCCCCC)=O; salicylic acid hexyl ester;SALICYLIC ACID, HEXYL ESTER; Salicylic acid, hexyl ester (6CI,7CI,8CI); Salicylic acid-hexyl ester; Hexyl salicylate. CAS names: Benzoic acid, 2-hydroxy-, hexyl ester. : Benzoic Acid, 2-hydroxy-, 2-hexyl ester; Fragrance oil; Hexyl 2-hydroxybenzoate; hexylsalicylat; Salicylic acid, hexylester; Salicylic acix, hexylester; Trade names :Hexyl ο-hydroxybenzoate; n-Hexyl Salicylate
Salicylate d'hexyle ( HEXYL SALICYLATE)
Salicylic acid; o-Hydroxybenzoic acid; Phenol-2-carboxylic acid; Salonil; 2-Hydroxybenzoic acid; 2-Hydroxybenzenecarboxylic acid; 2-Carboxyphenol; o-Carboxyphenol; Acido O-idrossibenzoico; Acido Salicilico; 2-hydroxy-Benzoic Acid; o-Hydroxybenzoic Acid; 2-Hydroxybenzoic Acid; Kyselina 2-hydroxybenzoova (Czech); Kyselina Salicylova; Orthohydroxybenzoic Acid; cas no: 69-72-7
Salicylic acid ( Acide salicylique) hydroxy benzoic acid
Disodium pyrophosphate; Disodium dihydrogen diphosphate ;Diphosphoric acid, disodium salt; Disodium dihydrogen pyrophosphate; Disodium diphosphate; Sodium acid pyrophosphate, SAPP cas no:7758-16-9
Salvadora Persica
salvadora persica bark root extract; extract of the roots and bark of the mustard tree, salvadora persica l., moraceae; mswaki extract; mustard tree extract; peelu bark extract;toothbrush tree extract CAS NO:8007-40-7
Sambucus nigra
sambucus nigra extract; extract of the whole plant the elder, sambucus nigra l., caprifoliaceae; elderflower CAS NO:84603-58-7
Sandal Ağacı Yağı
SANDALWOOD OIL ;sandalwood oil; santalum album wood oil; arheol oil; oil sandalwood; saunders white oil CAS NO:8006-87-9
Sanguinaria canadensis
sanguinaria canadensis root extract ; extract of the roots of the blood root, sanguinaria canadensis l., papaveraceae; blood root extract; bloodroot root extract; extract of the roots of the blood root, sanguinaria canadensis l., papaveraceae; red- puccoon root extract; sanguinaria australis root extract; sanguinaria canadensis var. rotundifolia root extract; sanguinaria dilleniana root extract;sanguinaria root extract CAS NO:84929-48-6
Sanolin Blue NBL
cas no 69-72-7 o-Hydroxybenzoic acid; Phenol-2-carboxylic acid; Salonil; 2-Hydroxybenzoic acid; 2-Hydroxybenzenecarboxylic acid; 2-Carboxyphenol; o-Carboxyphenol; Acido O-idrossibenzoico (Italian); Acido Salicilico (Italian); 2-hydroxy-Benzoic Acid; o-Hydroxybenzoic Acid; 2-Hydroxybenzoic Acid; Kyselina 2-hydroxybenzoova (Czech); Kyselina Salicylova (Czech); Orthohydroxybenzoic Acid;
Sanolin Patent Blue V85 01
o-Hydroxybenzoic acid; Phenol-2-carboxylic acid; Salonil; 2-Hydroxybenzoic acid; 2-Hydroxybenzenecarboxylic acid; 2-Carboxyphenol; o-Carboxyphenol; Acido O-idrossibenzoico; Acido Salicilico; 2-hydroxy-Benzoic Acid; o-Hydroxybenzoic Acid; 2-Hydroxybenzoic Acid; Kyselina 2-hydroxybenzoova; Kyselina Salicylova; Orthohydroxybenzoic Acid CAS NO:69-72-7
Sanolin Tartrazine X 90
Salicylic acid; o-Hydroxybenzoic acid; Phenol-2-carboxylic acid; Salonil; 2-Hydroxybenzoic acid; 2-Hydroxybenzenecarboxylic acid; 2-Carboxyphenol; o-Carboxyphenol; Acido O-idrossibenzoico; Acido Salicilico; 2-hydroxy-Benzoic Acid; o-Hydroxybenzoic Acid; 2-Hydroxybenzoic Acid; Kyselina 2-hydroxybenzoova (Czech); Kyselina Salicylova; Orthohydroxybenzoic Acid; cas no: 69-72-7
SAPP 22 (PRAYLEV SLOWPYRO)
SAPP 22 (Praylev Slowpyro) is used as an acidulant, buffering agent, and leavening agent.
SAPP 22 (Praylev Slowpyro) helps maintain the pH level of a solution, preventing it from becoming too acidic or too basic.
SAPP 22 (Praylev Slowpyro) has a dough reaction rate of 22 - 28.

CAS Number: 7758-16-9
Molecular Formula: H5NaO7P2
Molecular Weight: 201.97
EINECS Number: 231-835-0

Synonyms: 7758-16-9, Disodium diphosphate, Sodium acid pyrophosphate, Disodium dihydrogen pyrophosphate, DISODIUM PYROPHOSPHATE, H5WVD9LZUD, disodium;[hydroxy(oxido)phosphoryl] hydrogen phosphate, MFCD00014246, Disodium acid pyrophosphate, Dinatriumpyrophosphat, Disodiumpytophosphate, Dinatriumpyrophosphat [German], Disodium dihydrogen diphosphate, Disodium dihydrogenpyrophosphate, HSDB 377, Pyrophosphoric acid, disodium salt, UNII-H5WVD9LZUD, Sodium pyrophosphate (Na2H2P2O7), EINECS 231-835-0, Sodium diphosphate dibasic, disodium hydrogen (hydrogen phosphonatooxy)phosphonate, Grahamsches salz, Glassy sodium phosphate, DSSTox_CID_8842, sodium dihydrogendiphosphate, EC 231-835-0, DSSTox_RID_78658, DSSTox_GSID_28842, SODIUMACIDPYROPHOSPHATE, Sodium pyrophosphate, dibasic, Sodium dihydrogen pyrophosphate, CHEMBL3184949, EINECS 272-808-3, Tox21_200813, DISODIUM PYROPHOSPHATE [HSDB], DISODIUM PYROPHOSPHATE [INCI], DISODIUM PYROPHOSPHATE [VANDF], AKOS015916169, AKOS024418779, SODIUM ACID PYROPHOSPHATE [MI], Diphosphoric acid, sodium salt (1:2), SODIUM ACID PYROPHOSPHATE [FCC], NCGC00258367-01, SODIUM ACID PYROPHOSPHATE [VANDF], CAS-68915-31-1, di-sodium dihydrogen pyrophosphate anhydrous.

SAPP 22 (Praylev Slowpyro) is used as a (tropically stable) acid carrier in baking powder, for improvement of flow properties in flour, for pH regulation, and in dental care products for prevention of tartar formation.
SAPP 22 (Praylev Slowpyro) gene is mapped to human chromosome 21q21.3.
Above this temperature, SAPP 22 (Praylev Slowpyro) is converted to the anhydrous form.

This is important for controlling the texture and appearance of certain food items.
In some food products, SAPP 22 (Praylev Slowpyro) may serve as an emulsifying agent.
SAPP 22 (Praylev Slowpyro) helps to stabilize and maintain the uniform distribution of water and oil-based ingredients, preventing separation and improving the overall texture of the product.

SAPP 22 (Praylev Slowpyro) can act as a sequestrant, which means it can bind to metal ions, helping to prevent their undesirable effects in food products, such as discoloration or off-flavors.
SAPP 22 (Praylev Slowpyro) is sometimes used in the meat processing industry to improve the texture and moisture retention of meat products.
SAPP 22 (Praylev Slowpyro) can enhance the binding properties of meat mixtures.

SAPP 22 (Praylev Slowpyro) is a source of phosphates, which can contribute to the nutritional profile of certain food products.
SAPP 22 (Praylev Slowpyro)is a white powdered, non-flammable substance that is odorless, and has a bitter taste.
SAPP 22 (Praylev Slowpyro) is an all-purpose phosphate commonly used in prepared mixes, commercial baking powders, and cake doughnut mixes.

SAPP 22 (Praylev Slowpyro) is often used as a sequestrant, buffering agent, and raising agent in baked foods, cheese and meat products.
SAPP 22 (Praylev Slowpyro), also known as disodium dihydrogen pyrophosphate, disodium pyrophosphate, is white crystalline powder, which has the relative density of 1.864 and can decompose into sodium metaphosphate when it is heated above 220℃.
SAPP 22 (Praylev Slowpyro) is easily soluble in water and can form chelates with Cu2+ and Fe2+.

SAPP 22 (Praylev Slowpyro) is a soluble protein generated by sequential cleavage with α and γ secretase.
SAPP 22 (Praylev Slowpyro) reacts in stages and is desirable in baking applications for its slow action.
SAPP 22 (Praylev Slowpyro) is a popular leavening agent found in baking powders.

SAPP 22 (Praylev Slowpyro) is available in a variety of grades that affect the speed of its action.
Because the resulting phosphate residue has an off-taste, SAPP 22 (Praylev Slowpyro) is usually used in very sweet cakes which mask the off-taste.
SAPP 22 (Praylev Slowpyro) and other sodium and potassium polyphosphates are widely used in food processing; in the E number scheme, they are collectively designated as E450, with the disodium form designated as E450(a).

In the United States, SAPP 22 (Praylev Slowpyro) is classified as generally recognized as safe (GRAS) for food use.
In canned seafood, it is used to maintain color and reduce purge during retorting.
Retorting achieves microbial stability with heat.

SAPP 22 (Praylev Slowpyro) is an acid source for reaction with baking soda to leaven baked goods.
In baking powder, SAPP 22 (Praylev Slowpyro) is often labeled as food additive E450.
In cured meats, it speeds the conversion of sodium nitrite to nitrite (NO−2) by forming the nitrous acid (HONO) intermediate, and can improve water-holding capacity.

SAPP 22 (Praylev Slowpyro) is also found in frozen hash browns and other potato products, where it is used to keep the color of the potatoes from darkening.
SAPP 22 (Praylev Slowpyro) can leave a slightly bitter aftertaste in some products, but "the SAPP taste can be masked by using sufficient baking soda and by adding a source of calcium ions, sugar, or flavorings.
SAPP 22 (Praylev Slowpyro) occurs as a white, crystalline powder.

SAPP 22 (Praylev Slowpyro) is soluble in water. The pH of a 1:100 aqueous solution is about.
SAPP 22 (Praylev Slowpyro) may contain a suitable aluminum and/or calcium salt to control the rate of reaction in leavening systems.
The baking industry is the largest user Sodium Acid Pyrophosphate within the food industry.

SAPP 22 (Praylev Slowpyro)s main function is the leavening reaction with Bicarbonate (baking powder).
To obtain high quality baked goods, an optimal leavening is required
SAPP 22 (Praylev Slowpyro) is Na2H2P2O7 with Chemical Formula.

SAPP 22 (Praylev Slowpyro) is a chemical derivative of phosphorus, an important element in life for all living things.
One of the most common elements. Foods, water, our body also occurs in natural.
SAPP 22 (Praylev Slowpyro) or sodium acid pyrophosphate is an inorganic compound consisting of sodium cations and pyrophosphate anion.

SAPP 22 (Praylev Slowpyro) is a white, water-soluble solid that serves as a buffering and chelating agent, with many applications in the food industry.
SAPP 22 (Praylev Slowpyro) is used as a fast fermentation agent, quality improver, puffer, buffer, etc. in food processing, and is often used as an acidic ingredient in synthetic puffing agents such as bread and pastries.
SAPP 22 (Praylev Slowpyro) is white powder or granule, soluble in water, insoluble in ethanol.

SAPP 22 (Praylev Slowpyro) is mainly used in Baked products, ferment powder, fermentation Speed control agent, instant noodles, biscuits, cakes and pastries, shorten fermentation time, prolong storage period.
Bread, cakes, bread and other foods are characterized by spongy porous tissue to create a soft taste.
In order to achieve this, a sufficient amount of gas must be kept in the dough.

The water vapor produced by the heating of the air and moisture in the material mixture during baking can cause the product to produce some spongy tissue, but the amount of gas is far from enough.
The vast majority of the gas required is provided by puffing agents.
A commonly used compound puffer is a carbon dioxide gas produced by the action of sodium bicarbonate and acidic salts.

SAPP 22 (Praylev Slowpyro) is a widely used acidic salt, which is used in a variety of baked and fried foods.
The ROR value of SAPP 22 (Praylev Slowpyro) is the gas production rate, which refers to sodium bicarbonate and sodium acid pyrophosphate, in the environment of wet dough, the amount of carbon dioxide
actually released at 8 minutes accounts for the proportion of the total carbon dioxide volume released by the theory.
SAPP 22 (Praylev Slowpyro), SAPP in petroleum production, it can be used as a dispersant in oil well drilling muds.

SAPP 22 (Praylev Slowpyro), SAPP can also be found in frozen hash browns and other potato products, where it is used to keep the color of the potatoes from darkening.
SAPP 22 (Praylev Slowpyro) is an inorganic compound consisting of sodium cations and pyrophosphate anion.
SAPP 22 (Praylev Slowpyro) serves as a buffering, chelating and leavening agent.

SAPP 22 (Praylev Slowpyro) also known as Di-sodium Di-phosphate is an inorganic compound of sodium and pyrophosphate.
SAPP 22 (Praylev Slowpyro) is white and soluble in water.
SAPP 22 (Praylev Slowpyro) is manufactured with double drying process like other Pyrophosphates due to heating needed at a high temperature.

SAPP 22 (Praylev Slowpyro) is an anhydrous white powdered material, which complies with the specifications of the current Food Chemicals Codex for Sodium Acid Pyrophosphate.
SAPP 22 (Praylev Slowpyro) is used as an acidulant, buffering agent, and leavening agent.
SAPP 22 (Praylev Slowpyro) has a dough reaction rate of 24 - 28.

SAPP 22 (Praylev Slowpyro) is an all-purpose phosphate commonly used in prepared mixes, commercial baking powders, and cake doughnut mixes.
SAPP 22 (Praylev Slowpyro), or SAPP, is used in the food industry.
More specially, SAPP 22 (Praylev Slowpyro) is used for certain types of baking powder and baking creams in addition to working as a leavening agent for prepared cake and doughnut mixes.

SAPP 22 (Praylev Slowpyro) maintains the natural white color of cooked potatoes.
SAPP 22 (Praylev Slowpyro) is TongVo's high quality product, acts as a buffer, leaven, modifier, emulsifier, nutrient and canning preservative in foods, oil drilling, detergent, chemical stabiliser.
SAPP 22 (Praylev Slowpyro), also called tetrasodium pyrophosphate or tetrasodium phosphate.

SAPP 22 (Praylev Slowpyro) is a colorless, transparent crystalline chemical compound.
SAPP 22 (Praylev Slowpyro) has various functions such as a blowing agent, buffering agent, emulsifier, thickener and sequestrant.
SAPP 22 (Praylev Slowpyro) is generally used in bakery products, canning seafood and preventing browning of potatoes.

SAPP 22 (Praylev Slowpyro), which is also used in soy-based products as an alternative to meat products, acts as a tartar control agent in toothpaste, serves to remove elements such as magnesium and calcium in oral secretions, and prevents the accumulation of these elements on the teeth.
SAPP 22 (Praylev Slowpyro), which is sometimes used in household detergents for the same purposes;
SAPP 22 (Praylev Slowpyro) prevents the accumulation of similar types of elements on the clothes, but due to the high phosphate content it contains, it causes pollution in the waters and causes the growth of algae in contaminated waters.

SAPP 22 (Praylev Slowpyro) also known as SAPP and Disodium Pyrophosphate is produced by heating sodium dihydrogen phosphate.
Applications include food &|beverage (popular leavening agent found in baking powder, used in very sweet cakes which mask the off-tast, canned seafood, it is used to maintain color and reduce purge, frozen hash browns and other potato products, where it is used to keep the color of the potatoes from darkening)|agriculture (pet food used in cat foods as a palatability additive, removal of hair and scurf in hog slaughter and feathers and scurf in poultry slaughter and |industrial (petroleum production, it can be used as a dispersant in oil well drilling muds, leather treatment to remove iron stains on hides, dairy
applications for cleaning, remove soapstone).

The gas production speed of compound puffer depends on the reaction speed of acid salt and sodium bicarbonate, and the SAPP 22 (Praylev Slowpyro) is fast, medium and slow according to different gas production speed.
Different products require different gas production speeds of SAPP.
The gas-producing rate of SAPP 22 (Praylev Slowpyro) is a range value, not a fixed value, and is commonly expressed by ROR.

SAPP 22 (Praylev Slowpyro) is Na2H2P2O7 with Chemical Formula.
SAPP 22 (Praylev Slowpyro) is a chemical derivative of phosphorus, an important element in life for all living things.
SAPP 22 (Praylev Slowpyro) are commonly used when certain common elements, such as sodium, calcium, potassium and aluminum, are combined with phosphate ions.

SAPP 22 (Praylev Slowpyro) also prevents discoloration in potatoes and sugar syrups.
In canned tuna, it prevents harmless struvite crystals from forming.
SAPP 22 (Praylev Slowpyro) is an inorganic compound consisting of sodium cations and pyrophosphate anion.

As a leavening acid which combines with baking soda to release carbon dioxide to improve the texture and volume of baked goods.
As a chelating agent to chelate iron to prevent discoloration in processed potato.
SAPP 22 (Praylev Slowpyro) is also known as Disodium pyrophosphate.

SAPP 22 (Praylev Slowpyro) chemical formula is (Na2H2P2O7).
SAPP 22 (Praylev Slowpyro) is widely used as thinner in oil well drilling muds and even as an industrial cleaner.
Aids in the removal of calcium and reduces pH in cement contaminated fluids.

At low concentration levels, it is fast-acting and effective.
SAPP 22 (Praylev Slowpyro) decreases the viscosity and gel strengths in freshwater drilling fluids.
Aids break up clay particles and sediments, which enables them to be extracted during oil well development.

SAPP 22 (Praylev Slowpyro) is used in the chemical clean up of fluids which have been contaminated by cement.
SAPP 22 (Praylev Slowpyro) is used as a deflocculant (thinner) in freshwater mud systems.
SAPP 22 (Praylev Slowpyro) is often used to break up mud rings when water drilling and is also used to thin out cement before cementing casing.

SAPP 22 (Praylev Slowpyro) is an inorganic compound with the chemical formula Na2H2P2O7.
SAPP 22 (Praylev Slowpyro) consists of sodium cations (Na+) and dihydrogen pyrophosphate anions (H2P2O2−7).
The aqueous solution can be hydrolyzed to phosphoric acid by heating with dilute sulfuric acid or dilute mineral acid.

SAPP 22 (Praylev Slowpyro) is usually used in food processing industry.
The leavening acid, SAPP 22 (Praylev Slowpyro) is an important component of double acting baking powder as well as self rising flour.
When crystallized from water, SAPP 22 (Praylev Slowpyro) forms a hexahydrate, but it dehydrates above room temperature.

SAPP 22 (Praylev Slowpyro) is a polyvalent anion with a high affinity for polyvalent cations, e.g. Ca2+.
SAPP 22 (Praylev Slowpyro) is mainly used in the bakery industry at a leavening agent.
May also be blended with other phosphates and used for water retention in processed meats, and used to maintain the appearance and texture of uncooked fruits and vegetables.

SAPP 22 (Praylev Slowpyro) is an anhydrous white powdered material, which complies with the specifications of the current Food Chemicals Codex for Sodium Acid Pyrophosphate.
SAPP 22 (Praylev Slowpyro) encodes a integral membrane protein.
SAPP 22 (Praylev Slowpyro) is a white, water-soluble solid that serves as a buffering and chelating agent, with many applications in the food industry.

SAPP 22 (Praylev Slowpyro) is solubility in water is 13g Na2H2P2O7/100g H2O at 20 °C, and 20g at 80°C.
The usual commercial SAPP 22 (Praylev Slowpyro) is the anhydrous, nonhygroscopic salt in powder form.
SAPP 22 (Praylev Slowpyro) is often used as a leavening agent in baked goods, such as bread, cakes, and pastries.

SAPP 22 (Praylev Slowpyro) releases carbon dioxide gas when exposed to heat, helping the dough rise and creating a light and airy texture in the final product.
SAPP 22 (Praylev Slowpyro) functions as a buffering agent in food and beverage products.

Melting point: decomposes 220℃ [MER06]
Density (hexahydrate): 1.86
vapor pressure: 0Pa at 20℃
storage temp.: -70°C
solubility: H2O: 0.1 M at 20 °C, clear, colorless
form: white powder
color: White to Off-White
PH: 3.5-4.5 (20℃, 0.1M in H2O, freshly prepared)
Water Solubility: Fully miscible in water. Insoluble in alcohol and ammonia.
λmax: λ: 260 nm Amax: 0.11
λ: 280 nm Amax: 0.09
Merck: 13,8643
Stability: Stable.
InChI: InChI=1S/Na.H4O7P2.H/c;1-8(2,3)7-9(4,5)6;/h;(H2,1,2,3)(H2,4,5,6);
InChIKey: IQTFITJCETVNCI-UHFFFAOYSA-N
SMILES O(P(O)(O)=O)P(O)(O)=O.[NaH]
LogP: -3.420 (est)

Regular SAPP 22 (Praylev Slowpyro) is used in cakes, sponges and refrigerated dough where a slower reactivity is desired.
SAPP 22 (Praylev Slowpyro) is advisable to wear PPE while mixing all powdered products.
Avoid skin contact and do not inhale dust or allow contact with eyes.

In standard water drilling operations, the usual procedure to apply SAPP 22 (Praylev Slowpyro) is to add one viscosity cup directly into the drill pipe at each connection.
In areas with very reactive clays, increased treatments will be required.
SAPP 22 (Praylev Slowpyro) is polyvalent, and acts as a Lewis base, so is effective at binding polyvalent cations.

SAPP 22 (Praylev Slowpyro) is used during the phosphating process of metal treatment.
SAPP 22 (Praylev Slowpyro) is used as a builder in acid cleaners.
SAPP 22 (Praylev Slowpyro) is used to sequester metals in processed potatoes.

SAPP 22 (Praylev Slowpyro) is also termed sapp, sodium acid pyrophosphate, acid sodium pyrophosphate, disodium diphosphate, and disodium dihydrogen pyrophosphate.
SAPP 22 (Praylev Slowpyro) is a white, water-soluble that serves as a buffering and chelating agent, with many applications in the food industry.
When crystallised from water, SAPP 22 (Praylev Slowpyro) forms hexahydrate, but it dehydrates above room temperature.

SAPP 22 (Praylev Slowpyro) is a polyvalent anion with a high affinity for polyvalent cations.
SAPP 22 (Praylev Slowpyro) is a popular leavening agent found in baking powders.
SAPP 22 (Praylev Slowpyro) combines with sodium bicarbonate to release carbon dioxide.

SAPP 22 (Praylev Slowpyro) is available in a variety of grades that effect the speed of its action.
Because the resulting phosphate residue has an off-taste, SAPP 22 (Praylev Slowpyro) is usually used in very sweet cakes which mask the taste.
SAPP 22 (Praylev Slowpyro) is designated in the USA as generally recognized as safe for food use.

SAPP 22 (Praylev Slowpyro) is used in canned seafood to maintain color and reduce purge during retorting.
Retorting achieves microbial stability with heat.
SAPP 22 (Praylev Slowpyro) is an acid source for reaction with baking soda to leaven baked goods.

In baking powdeer, SAPP 22 (Praylev Slowpyro) is often labeled as food additive E450.
In cured meats, SAPP 22 (Praylev Slowpyro) speeds the conversion of sodium nitrite to nitrite by forming the nitrous acid intermediate, and can improve waterholding capacity
Amyloid precursor protein α is an α-secretase-cleaved soluble protein that has been shown to have neuroprotective properties.

SAPP 22 (Praylev Slowpyro) is derived from amyloid precursor protein.
Several G protein-coupled receptors are known to activate α-secretase-dependent processing of APP.
SAPP 22 (Praylev Slowpyro) also sequesters Fe and Cu.

SAPP 22 (Praylev Slowpyro) is moderately soluble in water, with a solubility of 15 g in 100 ml at 25°c.
SAPP 22 (Praylev Slowpyro) is used in doughnuts and biscuits for its variable gas release rate during the mixing, bench action, and baking process.
SAPP 22 (Praylev Slowpyro) is used in baking powder as a leavening agent.

SAPP 22 (Praylev Slowpyro) is used in canned fish products to reduce the level of undesired struvite crystals (magnesium ammonium phosphate hexahydrate) by complexing the magnesium.
SAPP 22 (Praylev Slowpyro) is a buffering and chelating agent, with many food and industrial uses.
SAPP 22 (Praylev Slowpyro) is used to disperse and displace drilling muds to avoid mud being affected by cement contamination.

Solids carrying fluid or drilling mud must be removed from the perforation channels and the rock face to allow a good cement bond and complete fill-up of the voids.
Incorporating SAPP 22 (Praylev Slowpyro) into the spacer will help remove residual muds and provide a cleaner surface to which the cement can bond.
Those working with Sodium Acid Pyrophosphate (SAPP) should wear appropriate Personal Protective Equipment, including dust masks and eye protection.

SAPP 22 (Praylev Slowpyro) is an inorganic compound consisting of sodium cations and pyrophosphate anion.
SAPP 22 (Praylev Slowpyro) has neuroprotective, neurogenic and neurotrophic functions.
Amyloid precursor protein a also stimulates gene expression and protein expression.

SAPP 22 (Praylev Slowpyro) is one of the two acid components used in commercial baking powders.
SAPP 22 (Praylev Slowpyro) is reactive not only with sodium bicarbonate, but also with calcium salts, proteins and heat.
SAPP 22 (Praylev Slowpyro) gives baking powder the time and temperature element contributing to the "Double Acting" power.

Uses:
SAPP 22 (Praylev Slowpyro) is also used to stabilize the solution of hydrogen peroxide against reduction.
SAPP 22 (Praylev Slowpyro) is used in petroleum industry as a dispersant in oil well drilling muds.
SAPP 22 (Praylev Slowpyro) is an inorganic compound, which consists sodium cations and pyrophosphate anion.

This is white in color and has water-soluble solids, which serve as a buffering and chelating agent.
SAPP 22 (Praylev Slowpyro) is massively in various applications in Used as improving agent in food industry, pH regulating agent, metal ion complex agent, emulsion, dispersing agent and adhesive
agent.
SAPP 22 (Praylev Slowpyro) is applied in the processing of meat and aquatic products in order to hold water, keep the meat fresh and tender, stabilize the natural color and prevent fat from putridity.

SAPP 22 (Praylev Slowpyro) is used in the production of yeast powder and cheese etc.
As a chelating agent to chelate iron to prevent discoloration in processed potato.
For industry, SAPP 22 (Praylev Slowpyro) is applied to oil area as a drilling fluid.

SAPP 22 (Praylev Slowpyro) Used as starter, used for baking food and controlling fermentation speed; It is used for instant noodles to reduce the rehydration time of finished products and is not sticky or rotten; It is used in biscuits and pastries to shorten the fermentation time, reduce the damage rate of products, loosen and tidy gaps, and prolong the storage period.
Release to the environment of SAPP 22 (Praylev Slowpyro) can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).
Other release to the environment of SAPP 22 (Praylev Slowpyro) is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

SAPP 22 (Praylev Slowpyro) can be found in complex articles, with no release intended: vehicles and machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines). Sodium Acid Pyrophosphate (SAPP-28) can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), wood (e.g. floors, furniture, toys) and plastic (e.g. food packaging and storage, toys, mobile phones).
SAPP 22 (Praylev Slowpyro) is used in the following products: washing & cleaning products, fillers, putties, plasters, modelling clay, metal surface treatment products, non-metal-surface treatment products, hydraulic fluids, pH regulators and water treatment products, lubricants and greases, metal working fluids, heat transfer fluids, laboratory chemicals, leather treatment products, paper chemicals and dyes and textile treatment products and dyes.

SAPP 22 (Praylev Slowpyro) is used in the following areas: mining, building & construction work and scientific research and development.
SAPP 22 (Praylev Slowpyro) is used for the manufacture of: metals, fabricated metal products, machinery and vehicles, textile, leather or fur, pulp, paper and paper products and mineral products (e.g. plasters, cement).
Other release to the environment of SAPP 22 (Praylev Slowpyro) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

SAPP 22 (Praylev Slowpyro) is used in the following products: pH regulators and water treatment products, metal surface treatment products, non-metal-surface treatment products, hydraulic fluids, leather treatment products, lubricants and greases and metal working fluids.
Release to the environment of SAPP 22 (Praylev Slowpyro) can occur from industrial use: formulation of mixtures, in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), formulation in materials, in the production of articles and as processing aid.
Other release to the environment of SAPP 22 (Praylev Slowpyro) is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

SAPP 22 (Praylev Slowpyro) is anhydrous form, pyrophosphate salt used in buffers.
SAPP 22 (Praylev Slowpyro) is a leavening agent, preservative, sequestrant, and buffer which is mildly acidic with a ph of 4.1.
SAPP 22 (Praylev Slowpyro) is moderately soluble in water, with a solubility of 15 g in 100 ml at 25°c.

SAPP 22 (Praylev Slowpyro) is used in doughnuts and biscuits for its variable gas release rate during the mixing, bench action, and baking process.
SAPP 22 (Praylev Slowpyro) is used in baking powder as a leavening agent.
SAPP 22 (Praylev Slowpyro) is used in canned fish products to reduce the level of undesired struvite crystals (magnesium ammonium phosphate hexahydrate) by complexing the magnesium.

SAPP 22 (Praylev Slowpyro) is used to sequester metals in processed potatoes.
SAPP 22 (Praylev Slowpyro) is also termed sapp, sodium acid pyrophosphate, acid sodium pyrophosphate, disodium diphosphate, and disodium dihydrogen pyrophosphate.
In leather treatment, SAPP 22 (Praylev Slowpyro) can be used to remove iron stains on hides during processing.

SAPP 22 (Praylev Slowpyro) can stabilize hydrogen peroxide solutions against reduction.
SAPP 22 (Praylev Slowpyro) can be used with sulfamic acid in some dairy applications for cleaning, especially to remove soapstone.
When added to scalding water, it facilitates removal of hair and scurf in hog slaughter and feathers and scurf in poultry slaughter.

In petroleum production, SAPP 22 (Praylev Slowpyro) can be used as a dispersant in oil well drilling muds.
SAPP 22 (Praylev Slowpyro) is used in cat foods as a palatability additive.
SAPP 22 (Praylev Slowpyro) is used as a tartar control agent in toothpastes.

Release to the environment of SAPP 22 (Praylev Slowpyro) can occur from industrial use: in the production of articles, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates), in processing aids at industrial sites, formulation in materials and as processing aid.
Other release to the environment of SAPP 22 (Praylev Slowpyro) is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

SAPP 22 (Praylev Slowpyro) may be used as leavening acid which combines with baking soda to release carbon dioxide to improve the texture and volume of baked goods.
SAPP 22 (Praylev Slowpyro) is widely used as a leavening agent in baked goods, including bread, cakes, muffins, and pastries.
SAPP 22 (Praylev Slowpyro) helps create a light and fluffy texture by releasing carbon dioxide gas during the baking process.

In pancake mixes and batter formulations, SAPP 22 (Praylev Slowpyro) is used to provide leavening and contribute to the texture of the final product.
SAPP 22 (Praylev Slowpyro) is a key component of baking powder formulations.
When combined with a basic SAPP 22 (Praylev Slowpyro), it creates a double-acting baking powder, releasing gas both upon mixing and during baking.

Due to its ability to produce carbon dioxide gas quickly, SAPP 22 (Praylev Slowpyro) is utilized in instant pancake and waffle mixes, allowing for rapid leavening when the batter is mixed with water.
SAPP 22 (Praylev Slowpyro) acts as a dough conditioner in various dough formulations, improving the handling properties and the overall quality of the dough.
In the meat industry, SAPP 22 (Praylev Slowpyro) is employed as a phosphate source to enhance the water-binding capacity of meat products. This can result in improved juiciness and texture.

SAPP 22 (Praylev Slowpyro) may be used in certain cheese and dairy products to control pH and improve texture.
SAPP 22 (Praylev Slowpyro) can also function as a sequestrant to bind metal ions.
SAPP 22 (Praylev Slowpyro) can be used in seafood products, particularly in surimi and imitation seafood, to improve texture and enhance moisture retention.

In the production of potato-based snacks like chips and fries, SAPP 22 (Praylev Slowpyro) can be used as a leavening agent to achieve a desirable texture.
SAPP 22 (Praylev Slowpyro) also has a wide use in dairy and poultry processes.
SAPP 22 (Praylev Slowpyro) may be included in instant pudding and gelatin formulations to contribute to their texture and consistency.

SAPP 22 (Praylev Slowpyro) is used in the following products: pH regulators and water treatment products, leather treatment products, hydraulic fluids, metal surface treatment products, non-metal- surface treatment products, lubricants and greases and metal working fluids.
SAPP 22 (Praylev Slowpyro) is used in the following areas: mining and formulation of mixtures and/or re-packaging.
SAPP 22 (Praylev Slowpyro) is used for the manufacture of: chemicals, textile, leather or fur, pulp, paper and paper products, metals, fabricated metal products and machinery and vehicles.

SAPP 22 (Praylev Slowpyro) can be used as a leavening chemical for bread to help it rise.
SAPP 22 (Praylev Slowpyro) used in sausage to enhance flavor and color.
In french fries, the chemical reduces levels of a carcinogen called acrylamide, according to an article from the Center for Science in the Public Interest.

SAPP 22 (Praylev Slowpyro) also prevents discoloration in potatoes and sugar syrups.
In canned tuna, SAPP 22 (Praylev Slowpyro) prevents harmless struvite crystals from forming.

SAPP 22 (Praylev Slowpyro) is used in leather treatment to remove iron stains.
SAPP 22 (Praylev Slowpyro) is widely used globally in food industry for baking reaction purpose.

Safety Profile:
Moderately toxic by ingestion and subcutaneous routes.
Individuals with specific health concerns should consult with healthcare professionals or dietitians to determine appropriate dietary choices.
While rare, some individuals may be sensitive or allergic to specific food additives, including SAPP 22 (Praylev Slowpyro).

SAPP 22 (Praylev Slowpyro) in food products is subject to regulatory standards and guidelines.
An irritant to skin, eyes, and mucous membranes.
When heated to decomposition it emits toxic fumes of POx, and Na2O.,

SAPP 22 (Praylev Slowpyro) is a source of phosphorus, and excessive intake of phosphorus can be a concern for individuals with certain health conditions, such as kidney problems.
In such cases, high phosphorus intake may contribute to imbalances in mineral metabolism.

SAPP 22 (Praylev Slowpyro)'s important for food manufacturers to comply with these regulations to ensure the safety of the final products.
Consumers can rely on regulatory agencies to set permissible levels of food additives and monitor their use in the food industry.


SAPP 28 (SODIUM ACID PYRO PHOSPHATE)
Sarcosine; N-methylglycine; methyl glycine, N-methyl-; 2-(methylamino)acetic acid; SARCOSINE, N° CAS : 107-97-1, Nom INCI : SARCOSINE, Nom chimique : Glycine, N-methyl-. N° EINECS/ELINCS : 203-538-6. Ses fonctions (INCI). Agent d'entretien de la peau : Maintient la peau en bon état. (methylamino)acetic acid; (methylamino)-Acetic acid; (Methylamino)essigsäure [German]; (methylamino)ethanoic acid; 107-97-1 [RN]; 1699442 [Beilstein]; 203-538-6 [EINECS]; 4-04-00-02363 [Beilstein]; Acetic acid, (methylamino)-; Acide (méthylamino)acétique; Glycine, N-methyl- [ACD/Index Name]; Methylaminoethanoic acid; Methylglycine; MFCD00004279 [MDL number]; N-methylaminoacetic acid; N-Methylglycin [German] [ACD/IUPAC Name]; N-methyl-Glycine N-Methylglycine [ACD/IUPAC Name]; N-Méthylglycine [French] [ACD/IUPAC Name]; N-Methylglycocoll; SAR; SARCOSIN; Sarcosine; sarcosine zwitterion; sarcosinic acid; (methylamino)-Acetate ; (Methylamino)ethanoate; N-Methylaminoacetate; sarcosinate; (methylazaniumyl)acetate; 2-​(methylamino)​acetic acid; 2-(methylamino)acetic acid; 2-(methylazaniumyl)acetate; 2-(trideuteriomethylamino)acetic acid; 203-538-6MFCD00004279; 2-methylaminoacetic acid; 2-Methylaminoethanoic acid; 5-Chloro-1H-indazole-3-carboxylic acid [ACD/IUPAC Name]; CH3NHCH2COOH; Cocobetaine; H-Sar-OH; L-sarcosine; MeGly; methylaminoacetic acid; Methylamino-acetic acid; MGY; N-(Methyl)glycine; N-METHYL GLYCINE;N-Methyl-2-aminoethanoic acid ; N-Methyl-glycocoll; PI-45053; sarcosine standard; Sarcosine|N-methyl-glycine; Sarkosin; 肌氨酸 [Chinese]
SAPP 40 (PRAYLEV FASTPYRO)
SAPP 40 (Praylev Fastpyro) is a food grade white powder that can be used as an acid carrier for the production of baking powder, flour improver and manufacture of potato products.
SAPP 40 (Praylev Fastpyro) is a chemical derivative of phosphorus, which is an essential element for life in all living things.


CAS Number: 7758-16-9
EC Number: 231-835-0
E number: E450(i) (thickeners, ...)
Chemical formula: Na2H2P2O7



SYNONYMS:
Disodium Pyrophosphate, Disodium Dihydrogen Pyrophosphate, Disodium Dihydrogen Diphosphate, Acid Sodium Pyrophosphate, SAPP Powder FCC Pdr [SAPP 40], T/N: Unate SP 40, Sodium Acid Pyrophosphat, Thermphos: Acid Sodium Pyrophosphate 28 E 450i, Sodium Dihydrogen Pyrophosphate, Sodium Acid Pyrophosphate, E450(i), Disodium Pyrophosphate, Disodium dihydrogen diphosphate, Diphosphoric acid, disodium salt, Disodium dihydrogen pyrophosphate, Disodium diphosphate, Sodium acid pyrophosphate, SAPP, Diphosphoric Acid Disodium Salt, Disodium Dihydrogen Pyrophosphate, Disodium Pyrophosphate, E 450, SAPP Food Grade, E450(i), Disodium Pyrophosphate



SAPP 40 (Praylev Fastpyro) is one of the most common elements found in nature and occurs naturally in foods, water and in our bodies.
Phosphorus in our body; SAPP 40 (Praylev Fastpyro) participates in the structure of genes, teeth, bones and muscles.
Another important phosphorus derivative that we all use in our daily lives is phosphoric acid.


Orthophosphate salts are formed from phosphoric acid, a tribasic acid, by changing the position of one, two or all three hydrogen ions with other positive ions.
Phosphoric acid is combined with other elements such as calcium, potassium and sodium and turns into phosphates thanks to heat.


The main characteristics of phosphates that determine their important properties are; chain length and pH.
These affect the usefulness of phosphates, promoting solubility through their buffering power, chelating power, dispersion and absorptive abilities.
Phosphates are mostly used by combining some common elements such as sodium, calcium, potassium and aluminum with phosphate ions.


The rapid increase in the world population, the tendency to increase people's living standards and rapid industrialization have led to the demand for prepared foods, and as a result, the manufacturing of foods has become a branch of industry.
Thus, processed food items have become extremely diversified and the number of food additives used in the production phase has increased dramatically.


Many factors such as the development of production techniques, increasing consumer taste, reducing losses, ease of distribution and the production of brand new foods with different methods have contributed to this increase.
In many foods, spontaneous reactions called "oxidation" occur between the components that make up the product and the oxygen in the air.
It is always possible to feel too little or too much.


These kinds of reactions that cause quality deterioration are unacceptable events in the food industry.
The quality reduction mentioned here occurs in the form of changes in quality, odor and taste, breakdown of some nutritional elements and the formation of toxic compounds.


The autoxidation phenomenon in fat and fatty foods is of great importance both in terms of nutritional physiology and technological-economic aspects.
Antioxidants are used in cases where autoxidation cannot be prevented by physiological and technological methods.
Antioxidants are also defined as compounds that prevent or delay oxidative degradation in food products.


SAPP 40 (Praylev Fastpyro) is a food grade white powder that can be used as an acid carrier for the production of baking powder, flour improver and manufacture of potato products.
SAPP 40 (Praylev Fastpyro) is also known as Disodium pyrophosphate.
SAPP 40 (Praylev Fastpyro)'s chemical formula is (Na2H2P2O7).


SAPP 40 (Praylev Fastpyro) is a white, crystalline powder or granular substance.
SAPP 40 (Praylev Fastpyro) is an inorganic compound composed of sodium cation and pyrophosphate anion.
SAPP 40 (Praylev Fastpyro) is a white, water-soluble solid that can be used as a buffer and chelating agent and has many applications in the food industry.


When crystallized from water, SAPP 40 (Praylev Fastpyro) forms hexahydrate but dehydrates above room temperature.
Pyrophosphate is a polyvalent anion with a high affinity for polyvalent cations, for example, calcium ions.
SAPP 40 (Praylev Fastpyro) is a white powder.


SAPP 40 (Praylev Fastpyro) is a popular leavening agent found in baking powders.
SAPP 40 (Praylev Fastpyro) combines with sodium bicarbonate to release carbon dioxide.
SAPP 40 (Praylev Fastpyro) is available in a variety of grades that affect the speed of its action.


SAPP 40 (Praylev Fastpyro) is an anhydrous white powdered material, which complies with the specifications of the current Food Chemicals Codex for Sodium Acid Pyrophosphate.
SAPP 40 (Praylev Fastpyro) is a stabilizer.
SAPP 40 (Praylev Fastpyro) improves the consistency of the product, slows down the oxidation process of the product.


SAPP 40 (Praylev Fastpyro) increases moisture-binding and emulsifying ability.
SAPP 40 (Praylev Fastpyro) has a high reaction rate (36-40% CO2 in 8 minutes).
SAPP 40 (Praylev Fastpyro) is a white crystalline powder.


SAPP 40 (Praylev Fastpyro) is dissolve in water.
The pH of a 1:100 aqueous solution of SAPP 40 (Praylev Fastpyro) is about 4.
SAPP 40 (Praylev Fastpyro) may contain suitable aluminum and/or calcium salts to control reaction rates in disintegrating systems.


SAPP 40 (Praylev Fastpyro) has a sodium acid pyrophosphate food grade and an appearance of hygroscopic white powder without foreign matters.
SAPP 40 (Praylev Fastpyro) - also known as Leavening Grade 40 Sodium Acid Pyrophosphate or Disodium Pyrophosphate - is a white crystalline powder with a molecular formula of Na2H2P2O7.


SAPP 40 (Praylev Fastpyro) is certified FCC IV and Kosher.
SAPP 40 (Praylev Fastpyro) is a food grade.
SAPP 40 (Praylev Fastpyro) is a white crystalline powder.


SAPP 40 (Praylev Fastpyro) has a sodium acid pyrophosphate food grade and an appearance of hygroscopic white powder without foreign matters.
SAPP 40 (Praylev Fastpyro) is an anhydrous white powdered material, which complies with the specifications of the current Food Chemicals Codex for Sodium Acid Pyrophosphate.



USES and APPLICATIONS of SAPP 40 (PRAYLEV FASTPYRO):
SAPP 40 (Praylev Fastpyro) is speedly fermentation, water retaining agent and quality improver, used in bread, biscuits, meat, aquatic products and so on.
As quality improver, SAPP 40 (Praylev Fastpyro) enhances complexation,PH value and Ionic strength.


SAPP 40 (Praylev Fastpyro) is a sodium salt of pyrophosphoric acid and is commonly used as a food additive and in various industrial applications.
SAPP 40 (Praylev Fastpyro) has unique chemical properties that make it versatile in different processes.
SAPP 40 (Praylev Fastpyro) acts as a leavening agent in food production, helping dough rise and creating a light texture in baked goods.


In addition to its culinary uses, SAPP 40 (Praylev Fastpyro) is utilized as a buffering agent, stabilizer, and emulsifier in food processing.
SAPP 40 (Praylev Fastpyro) also finds application as a corrosion inhibitor, pH adjuster, and chelating agent in various industries.
SAPP 40 (Praylev Fastpyro)’s multifunctionality and compatibility with other ingredients make it a valuable component in many formulations.


SAPP 40 (Praylev Fastpyro) is widely used as thinner in oil well drilling muds and even as an industrial cleaner.
SAPP 40 (Praylev Fastpyro) decreases the viscosity and gel strengths in freshwater drilling fluids.
SAPP 40 (Praylev Fastpyro) is used actively thins out reactive clays.


SAPP 40 (Praylev Fastpyro) aids break up clay particles and sediments, which enables them to be extracted during oil well development.
SAPP 40 (Praylev Fastpyro) is used in the chemical clean up of fluids which have been contaminated by cement.
SAPP 40 (Praylev Fastpyro) is used as a deflocculant (thinner) in freshwater mud systems.


SAPP 40 (Praylev Fastpyro) is often used to break up mud rings when water drilling and is also used to thin out cement before cementing casing.
In cementing applications, SAPP 40 (Praylev Fastpyro) is used for two primary purposes.
SAPP 40 (Praylev Fastpyro) is generally used in bakery products, canning seafood and preventing potatoes from browning.


SAPP 40 (Praylev Fastpyro), which is also used in soy-based products similar to meat products, serves as a tartar control agent in toothpaste, serves to remove magnesium and calcium-like elements in oral secretion, and prevents the accumulation of these elements on the teeth.
SAPP 40 (Praylev Fastpyro), which is also sometimes used in household detergents for the same purposes.


SAPP 40 (Praylev Fastpyro) prevents the accumulation of similar types of elements on clothes, but due to its high phosphate content, it causes pollution in water and opens the door to the development of algae in contaminated water.
SAPP 40 (Praylev Fastpyro) is a popular leavening agent found in baking powders, which used as a constituent of blanching solutions for preventing after-cooking darkening of potatoes.


In addition, SAPP 40 (Praylev Fastpyro) is used as a general buffer and acidifying agent in.
SAPP 40 (Praylev Fastpyro) may be used In non-dairy creams, SAPP NL-170, is added to protect the proteins from heat dehydration, to stabilize the fat emulsion, and to stabilize the product along with many other formulations.


SAPP 40 (Praylev Fastpyro) is anhydrous white powder, free flowing, odorless, tasteless and food-grade.
Food uses of SAPP 40 (Praylev Fastpyro): Bakery, Functioal food, Convenience.
SAPP 40 (Praylev Fastpyro) is mainly used in the bakery industry at a leavening agent.


SAPP 40 (Praylev Fastpyro) may also be blended with other phosphates and used for water retention in processed meats, and used to maintain the appearance and texture of uncooked fruits and vegetables.
SAPP 40 (Praylev Fastpyro) is used as a leavening agent for bakery.
SAPP 40 (Praylev Fastpyro) has a reaction rate of 40 and functions as a leavening agent, preservative, sequestrant, and buffering agent.


SAPP 40 (Praylev Fastpyro) is commonly used in doughnuts, biscuits, baking powder, canned fish, and processed potatoes.
SAPP 40 (Praylev Fastpyro) is used as a leavening agent for bakery.
SAPP 40 (Praylev Fastpyro) is used as buffering agent, leavening agent, sequestrant agent.


SAPP 40 (Praylev Fastpyro) can be used in canned food, ham, meat,baking powder and so on.
SAPP 40 (Praylev Fastpyro) is used as a starter for cooking foods and controlling the rate of fermentation.
SAPP 40 (Praylev Fastpyro) is used in instant noodles to reduce the rehydration time of finished products and is not sticky or flimsy.


SAPP 40 (Praylev Fastpyro) can be used in making biscuits and cakes, can shorten fermentation time, reduce product damage rate, loosen and regulate pores, prolong storage time.
SAPP 40 (Praylev Fastpyro) is used as an acidulant, buffering agent, and leavening agent.


SAPP 40 (Praylev Fastpyro) has a dough reaction rate of 37 - 42.
SAPP 40 (Praylev Fastpyro) is a fast acting leavening phosphate typically used in bakery applications such as cake doughnuts mixes, cake mixes, breadings, and batters.


SAPP 40 (Praylev Fastpyro) is used food additives.
SAPP 40 (Praylev Fastpyro) is used as an acidulant, buffering agent, and leavening agent.
SAPP 40 (Praylev Fastpyro) has a dough reaction rate of 37 - 42.


-SAPP 40 (Praylev Fastpyro) is Baking powder, used in baking and to control the fermenting speed, to increase the producing strength.
SAPP 40 (Praylev Fastpyro) is used in instant noodles to reduce time after subjecting to water.
SAPP 40 (Praylev Fastpyro) is also used in biscuits and cakes, to reduce fermenting time, to decrease the destroying, to maintain the clear gaps, finally to extend products storage.


-Contaminated drilling mud can result in fluid loss, thickening time, and viscosity.
SAPP 40 (Praylev Fastpyro) is used to disperse and displace drilling muds to avoid mud being affected by cement contamination.

-Solids carrying fluid or drilling mud must be removed from the perforation channels and the rock face to allow a good cement bond and complete fill-up of the voids.
Incorporating SAPP 40 (Praylev Fastpyro) into the spacer will help remove residual muds and provide a cleaner surface to which the cement can bond.


-In standard water drilling operations, the usual procedure to apply SAPP 40 (Praylev Fastpyro) is to add one viscosity cup directly into the drill pipe at each connection.
In areas with very reactive clays, increased treatments will be required.
When using to thin the mud before cementing, mix as needed to the circulating mud system.


-Sodium Acid Pyrophosphate Uses in Water Treatment:
SAPP 40 (Praylev Fastpyro) has limited direct uses in water treatment processes.
However, SAPP 40 (Praylev Fastpyro) can indirectly contribute to certain aspects of water treatment.

SAPP 40 (Praylev Fastpyro) is sometimes employed as a pH adjuster and buffering agent in water treatment applications where precise pH control is necessary.
SAPP 40 (Praylev Fastpyro) can help stabilize and maintain the desired pH range, optimizing treatment processes.

Additionally, SAPP 40 (Praylev Fastpyro) can act as a sequestering agent, chelating metal ions and preventing their precipitation or interference with water treatment chemicals.

SAPP 40 (Praylev Fastpyro)'s ability to bind with metal ions aids in minimizing scaling and maintaining the efficiency of water treatment equipment.
While its direct applications in water treatment may be limited, SAPP 40 (Praylev Fastpyro)’s properties make it valuable in specific instances where pH adjustment and metal sequestration are crucial for effective water treatment operations.



FUNCTIONAL APPLICATION OF SAPP 40 (PRAYLEV FASTPYRO):
*Reaction enhancer;
*emulsifier;
*baking powder;
*complexing agent.



PREPARATION AND PROCEDURES OF SAPP 40 (PRAYLEV FASTPYRO):
Those working with SAPP 40 (Praylev Fastpyro) should wear appropriate Personal Protective Equipment, including dust masks and eye protection.
SAPP 40 (Praylev Fastpyro) is advisable to wear PPE while mixing all powdered products.



FUNCTION OF SAPP 40 (PRAYLEV FASTPYRO):
SAPP 40 (Praylev Fastpyro) is used in canned seafood to maintain color and reduce purge during retorting.
Retorting achieves microbial stability with heat.
In cured meats, SAPP 40 (Praylev Fastpyro) speeds the conversion of sodium nitrite to nitrite (NO2-) by forming the nitrous acid (HONO) intermediate, and can improve water-holding capacity.
SAPP 40 (Praylev Fastpyro) is also found in frozen hash browns and other potato products, where it is used to keep the color of the potatoes from darkening.



KEY ADVANTAGES OF SAPP 40 (PRAYLEV FASTPYRO):
• SAPP 40 (Praylev Fastpyro) aids in the removal of calcium and reduces pH in cement contaminated fluids.
• At low concentration levels, SAPP 40 (Praylev Fastpyro) is fast-acting and effective.



KEY PROPERTIES OF SAPP 40 (PRAYLEV FASTPYRO):
*leavening acid,
*sequestrant,
*dispersant,
*pH buffer agent.



PHYSICAL and CHEMICAL PROPERTIES of SAPP 40 (PRAYLEV FASTPYRO):
Chemical formula: Na2H2P2O7
Molar mass: 221.94 g/mol
Appearance: White odorless powder
Density: 2.31 g/cm3
Melting point: >600 °C
Solubility in water: 11.9 g/100 mL (20 °C)
Refractive index (nD): 1.4645 (hexahydrate)
CAS No.: 7758-16-9
EINECS No.: 231-835-0

MF: Na2H2P2O7
Molecular weight: 221.94
Appearance: White Powder
Chemical Formula: Na2H2P2O7
Physical State: White crystalline powder or granules
Solubility: Soluble in water
pH: Acidic
Density: Approximately 1.86 g/cm³
Melting Point: Decomposes above 220 °C (428 °F)

Odor: Odorless
Stability: Stable under normal conditions
PH: 4 To 4.5 %
Loss on drying: <2%
Matter Insoluble In water: <0.5
P205: Min 62%
Heavy metals as Pb: <0.01%
Assay: >90%
Melting point: decomposes 220℃
density (hexahydrate): 1.86

vapor pressure: 0 Pa at 20℃
storage temp.: -70°C
solubility: H2O: 0.1 M at 20 °C, clear, colorless
form: white powder
color: White to Off-White
PH: 3.5-4.5 (20℃, 0.1M in H2O, freshly prepared)
Water Solubility: Fully miscible in water.
Insoluble in alcohol and ammonia.
λmax: λ: 260 nm Amax: 0.11
λ: 280 nm Amax: 0.09

Merck: 13,8643
Stability: Stable.
Product Name: Disodium pyrophosphate
Other Name: Diphosphoric acid,sodium salt (1:2)
CAS No.: 7758-16-9
Molecular Formula: H4O7P2.2Na
Molecular Weight: 221.939
Exact Mass: 221.907
EC Number: 231-835-0
UNII: H5WVD9LZUD DSS
Tox ID: DTXSID8028842
Color/Form: White crystalline powder

HScode: 28353990
Categories:Leavening Agent
PSA: 149.57 XLogP3: 0.0648
Appearance: white powder
Density: 2.311 g/cm3 (25°C)
Melting Point: 988°C
Water Solubility: H2O: 0.1 M at 20 °C, clear, colorless
Storage Conditions: Warehouse ventilation dry at low temperature
PH:Between 3,7 and 5,0 (1 % solution)
Chemical formula: Na2H2P2O7
Molecular Weight: 221.94

White crystalline powder or granules
Soluble in water
Odor: Odorless
Molecular Weight: 221.94 g/mol
White color
pH (1 percent soln/water): 3.7 – 5.0 (1 percent aqueous solution)
Boiling Point: Not available.
Melting Point: Decomposes. (220 degrees or 428 degrees F)
Density: 2.31 g/cm3
Water solubility: 11.9 g/ml (20 degrees)
Melting Point: >600 degrees



FIRST AID MEASURES of SAPP 40 (PRAYLEV FASTPYRO):
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of SAPP 40 (PRAYLEV FASTPYRO):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of SAPP 40 (PRAYLEV FASTPYRO):
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of SAPP 40 (PRAYLEV FASTPYRO):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
required
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of SAPP 40 (PRAYLEV FASTPYRO):
-Precautions for safe handling:
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of SAPP 40 (PRAYLEV FASTPYRO):
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


SAPP SODIUM ACID PYROPHOSPHATE
SAPP Sodium Acid Pyrophosphate is a popular leavening agent found in baking powders.
SAPP Sodium Acid Pyrophosphate combines with sodium bicarbonate to release carbon dioxide.


CAS Number: 7758-16-9
EC Number: 231-835-0
Chemical Formula: Na2H2P2O7



SYNONYMS:
Diphosphoric Acid Disodium Salt, Disodium Dihydrogen Pyrophosphate, Disodium Pyrophosphate, E 450, SAPP, SAPP Food Grade, SAPP, DisodiuM pytophospha, Disodium Pyrophosphate, Disodium pytophosphate, Sodium Acid Pyrophosphate, Dentin sialophosphoprotein, Sodium pyrophosphate dibasic, disodium phosphonato phosphate, Diphosphoric acid, disodium salt, disodium dihydrogenpyrophosphate, Disodium Dihydrogen Pyrophosphate, TwosodiuM pyrophosphatetwo hydrogen, SODIUM PYROPHOSPHATE DIBASIC BIOULTR, Food Grade Sodium Acid Pyrophosphate, Amyloid Precursor Protein β, Secreted, di-sodium dihydrogen pyrophosphate anhydrous, SodiuM pyrophosphate dibasic practical grade, Diphosphoric acid, disodium salt, Disodium dihydrogen pyrophosphate, Disodium diphosphate, Sodium acid pyrophosphate, SAPP, disodium dihydrogen pyrophosphate, disodium pyrophosphate, SAPP, SAPP Powder FCC PODR K SAPP-28, Sodium Acid Pyrophosphate FCC Powder Kosher [SAPP 28], SAPP, Hi-B283, Disodium dihydrogen diphosphate, Diphosphoric acid, disodium salt, Disodium dihydrogen pyrophosphate, Disodium diphosphate, Sodium acid pyrophosphate, SAPP, Diphosphoric Acid Disodium Salt, Disodium Dihydrogen Pyrophosphate, SAPP, Disodium pyrophosphate, Disodium dihydrogen diphosphate, Disodium Diphosphate, Disodium Pyrophosphate, SAPP, Disodium Pyrophosphate, Disodium Diphosphate, Disodium Dihydrogen Diphosphate, Disodium Dihydrogen Pyrophosphate, Diphosphoric Acid, Disodium Salt, Pyrophosphoric Acid, Disodium Salt, Disodium pyrophosphate, Disodium diphosphate, Disodium dihydrogen pyrophosphate, Acid sodium pyrophosphate Disodium, Disodium Pyrophosphate, Disodium Diphosphate, Disodium Dihydrogen Diphosphate, Disodium Dihydrogen Pyrophosphate, Diphosphoric Acid, Disodium Salt, Pyrophosphoric Acid, Disodium Salt,



SAPP Sodium Acid Pyrophosphate is an inorganic compound consisting of sodium cations and pyrophosphate anion.
SAPP Sodium Acid Pyrophosphate is a white, water-soluble that serves as a buffering and chelating agent, with many applications in the food industry.
When crystallised from water, SAPP Sodium Acid Pyrophosphate forms hexahydrate, but it dehydrates above room temperature.


SAPP Sodium Acid Pyrophosphate is a polyvalent anion with a high affinity for polyvalent cations.
SAPP Sodium Acid Pyrophosphate is a popular leavening agent found in baking powders.
SAPP Sodium Acid Pyrophosphate combines with sodium bicarbonate to release carbon dioxide.


SAPP Sodium Acid Pyrophosphate is extensively used in food processing, as in canned seafood, cured meat, bakery and potato products, to adjust the pH, maintain color, improve flavour and improve the water-holding capacity.
The leavening acid, SAPP Sodium Acid Pyrophosphate is an important component of double acting baking powder, as well as self-rising flour.


SAPP Sodium Acid Pyrophosphate reacts in stages and is desirable in baking applications for its slow action.
SAPP Sodium Acid Pyrophosphate is an inorganic compound that is often used as a leavening agent in the baking industry.
SAPP Sodium Acid Pyrophosphate is white powder or granular in appearance.


SAPP Sodium Acid Pyrophosphate is soluble in water.
SAPP Sodium Acid Pyrophosphate is a white, water-soluble solid that serves as a buffering and chelating agent, with many applications in the food industry.
When crystallized from water, SAPP Sodium Acid Pyrophosphate forms a hexahydrate, but it dehydrates above room temperature.


Pyrophosphate is a polyvalent anion with a high affinity for polyvalent cations, e.g., Ca2+.
SAPP Sodium Acid Pyrophosphate is a popular leavening agent found in baking powders.
SAPP Sodium Acid Pyrophosphate combines with sodium bicarbonate to release carbon dioxide.


SAPP Sodium Acid Pyrophosphate is a food-grade chemical often used in the culinary industry as a leavening agent, as well as an emulsifier, a buffering agent, and a texturizer.
SAPP Sodium Acid Pyrophosphate is available in a variety of grades that effect the speed of its action.


SAPP Sodium Acid Pyrophosphate is an inorganic compound with the chemical formula Na2H2P2O7.
SAPP Sodium Acid Pyrophosphate consists of sodium cations (Na+) and dihydrogen pyrophosphate anions (H2P2O2−7).
SAPP Sodium Acid Pyrophosphate is a white, water-soluble solid that serves as a buffering and chelating agent, with many applications in the food industry.


When crystallized from water, SAPP Sodium Acid Pyrophosphate forms a hexahydrate, but it dehydrates above room temperature.
Pyrophosphate is a polyvalent anion with a high affinity for polyvalent cations, e.g. Ca2+.
SAPP Sodium Acid Pyrophosphate is produced by heating sodium dihydrogen phosphate:
2 NaH2PO4 → Na2H2P2O7 + H2O


SAPP Sodium Acid Pyrophosphate can leave a slightly bitter aftertaste in some products, but "the SAPP taste can be masked by using sufficient baking soda and by adding a source of calcium ions, sugar, or flavorings
SAPP Sodium Acid Pyrophosphate is a white powder soluble in water giving acidic solutions.


Food Grade Sodium Acid Pyrophosphate is available in two grades; medium acting leavening powder (SAPP 28) and fast acting leavening powder (SAPP 40).
The two grades offer a selection based on their rate of reaction with bicarbonate during the mixing of doughs or batters.
SAPP Sodium Acid Pyrophosphate is an inorganic compound consisting of sodium cations and pyrophosphate anions.


SAPP Sodium Acid Pyrophosphate is a food additive whose role is to improve the quality and stability of food products.
SAPP Sodium Acid Pyrophosphate is one of the two acid components used in commercial baking powder.
SAPP Sodium Acid Pyrophosphate is a white powder commonly used in food processing to adjust the pH, maintain color, improve the water-holding capacity and reduce purge during retorting.


SAPP Sodium Acid Pyrophosphate is a white granular powder that is used as a rapid fermenting agent.
SAPP Sodium Acid Pyrophosphate can be applied to acid component of synthetic swelling agent, such as bread and cake.
Blended with other phosphates SAPP Sodium Acid Pyrophosphate can be applied to water retention of meat product, such as canned meat, cooked ham, and instant noodles.


SAPP Sodium Acid Pyrophosphate is white monoclinic crystal fine powder, active melt, hygroscopic, soluble in water, and insoluble in ethanol.
SAPP Sodium Acid Pyrophosphate is a food moisture retention agent allowed by my country's regulations.
SAPP Sodium Acid Pyrophosphate is anhydrous white powder, free flowing, odorless, tasteless and food-grade.


SAPP Sodium Acid Pyrophosphate meets the specifications of the current Code of Chemicals Food for sodium acid pyrophosphate.
SAPP Sodium Acid Pyrophosphate may be used In non-dairy creams, SAPP NL-170, is added to protect the proteins from heat dehydration, to stabilize the fat emulsion, and to stabilize the product along with many other formulations.


SAPP Sodium Acid Pyrophosphate is designated in the USA as generally recognized as safe for food use.
SAPP Sodium Acid Pyrophosphate is an acid source for reaction with baking soda to leaven baked goods.
Store SAPP Sodium Acid Pyrophosphate in a cool, dry place.


SAPP Sodium Acid Pyrophosphate is a white crystalline powder
SAPP Sodium Acid Pyrophosphate also known as Di-sodium Di-phosphate is an inorganic compound of sodium and pyrophosphate.
SAPP Sodium Acid Pyrophosphate is white and soluble in water.


SAPP Sodium Acid Pyrophosphate is manufactured with double drying process like other Pyrophosphates due to heating needed at a high temperature.
SAPP Sodium Acid Pyrophosphate is an anhydrous white powdered material, which complies with the specifications of the current Food Chemicals Codex for Sodium Acid Pyrophosphate.


SAPP Sodium Acid Pyrophosphate is an inorganic compound consisting of sodium cations and pyrophosphate anion.
SAPP Sodium Acid Pyrophosphate is White powder, soluble in water, acidic property appeared in aqueous solution.
SAPP Sodium Acid Pyrophosphate is a white powder or granular.


SAPP Sodium Acid Pyrophosphate is one of the most popular chemicals, especially as a food additive.
SAPP Sodium Acid Pyrophosphate, also known as disodium pyrophosphate, is a white, water-soluble solid with the chemical formula Na2H2P2O7, which has many applications in the food industry.


SAPP Sodium Acid Pyrophosphate is produced by partial neutralization of food phosphoric acid with sodium hydroxide or sodium carbonate to form monosodium phosphate, which is then dehydrated at 250°C to form sodium pyrophosphate acid.
SAPP Sodium Acid Pyrophosphate readily dissolves and forms the pyrophosphate anion, which then interacts with the proteins in a fully cooked mixture to create a moist texture.


Also, SAPP Sodium Acid Pyrophosphate acts as a buffering agent for pulp in the pH range of 7.3 to 7.5, which affects the color of the final product.
SAPP Sodium Acid Pyrophosphate is also known as disodium pyrophosphate.
SAPP Sodium Acid Pyrophosphate is an anhydrous white powdered material, which complies with the specifications of the current Food Chemicals Codex for Sodium Acid Pyrophosphate.


Both SAPP Sodium Acid Pyrophosphate and GDL have a slightly bitter aftertaste.
SAPP Sodium Acid Pyrophosphate is an emulsifying agent in cheeses and related products.
SAPP Sodium Acid Pyrophosphate accelerates the cooking in processed meat and poultry products.


SAPP Sodium Acid Pyrophosphate is an anhydrous white powdered material, which complies with the specifications of the current Food Chemicals Codex for Sodium Acid Pyrophosphate.
SAPP Sodium Acid Pyrophosphate is an inorganic compound consisting of sodium cations and pyrophosphate anion.


SAPP Sodium Acid Pyrophosphate is a widely used acidic salt, which is used in a variety of baked and fried foods.
The ROR value of SAPP Sodium Acid Pyrophosphate is the gas production rate, which refers to sodium bicarbonate and sodium acid pyrophosphate, in the environment of wet dough, the amount of carbon dioxide actually released at 8 minutes accounts for the proportion of the total carbon dioxide volume released by the theory.


SAPP Sodium Acid Pyrophosphate has a dough reaction rate of 24 - 28.
SAPP Sodium Acid Pyrophosphate is an all-purpose phosphate commonly used in prepared mixes, commercial baking powders, and cake doughnut mixes.
SAPP Sodium Acid Pyrophosphate is available in white, crystalline powder or granules, that are odorless and has a slightly acidic taste.


The gas-producing rate of SAPP Sodium Acid Pyrophosphate is a range value, not a fixed value, and is commonly expressed by ROR.
SAPP Sodium Acid Pyrophosphate is soluble in water, but insoluble in alcohol.
solubility of SAPP Sodium Acid Pyrophosphate is 32.5% at 100°C.


SAPP Sodium Acid Pyrophosphate, also known as disodium dihydrogen pyrophosphate, disodium pyrophosphate.
SAPP Sodium Acid Pyrophosphate is white crystalline powder, which has the relative density of 1.864 and can decompose into sodium metaphosphate when it is heated above 220℃.


SAPP Sodium Acid Pyrophosphate is easily soluble in water and can form chelates with Cu2+ and Fe2+.
The aqueous solution of SAPP Sodium Acid Pyrophosphate can be hydrolyzed to phosphoric acid by heating with dilute sulfuric acid or dilute mineral acid.
SAPP Sodium Acid Pyrophosphate is an aerator grade of sodium acid pyrophosphate for bakery applications with a slow Rate of Reaction.


SAPP Sodium Acid Pyrophosphate has a rate of reaction of 26 - 30% CO2 in 8 minutes.
SAPP Sodium Acid Pyrophosphate is a crystalline acid salt Na2H2P2O7 of pyrophosphoric acid that has been added to hot dogs to give them color -called also sodium acid pyrophosphate.


SAPP Sodium Acid Pyrophosphate prevents change in colour darkening in potatoes and sugar syrups.
SAPP Sodium Acid Pyrophosphate is the slowest-acting sodium acid pyrophosphate.
SAPP Sodium Acid Pyrophosphate is a medium-speed fermentation agent and is usually a high-demand product.


Value range 24-30, fast product ROR 40 range is 35-43, slow fermentation agent ROR 15 range is 13-17, the demand is very small.
SAPP Sodium Acid Pyrophosphate, also known as disodium pyrophosphate, is an inorganic compound composed of sodium cation and pyrophosphate anion.
SAPP Sodium Acid Pyrophosphate is a white, water-soluble solid, commonly used as a buffer and chelating agent and has many applications in food processing industry.


SAPP Sodium Acid Pyrophosphate is an anhydrous white powdered material, which complies with the specifications of the current Food Chemicals Codex for Sodium Acid Pyrophosphate.
SAPP Sodium Acid Pyrophosphate has a dough reaction rate of 24 - 28.


SAPP Sodium Acid Pyrophosphate is an all-purpose phosphate commonly used in prepared mixes, commercial baking powders, and cake doughnut mixes.
SAPP Sodium Acid Pyrophosphate is white power.



USES and APPLICATIONS of SAPP SODIUM ACID PYROPHOSPHATE:
SAPP Sodium Acid Pyrophosphate is used in oil well drilling together with drilling mud to give a coating along the wall of the wells, by which the surface become hard and does not collapse while pipes are being inserted.
Common industrial uses include: Meat Processing, Potato-based Products, Dairy Products, Snacks, Bakery, and Seafood.


SAPP Sodium Acid Pyrophosphate is commonly used in the food industry as a leavening agent, acidulant, or buffer.
SAPP Sodium Acid Pyrophosphate releases Carbon Dioxide slowly upon reaction with Sodium Bicarbonate.
SAPP Sodium Acid Pyrophosphate can also be used to maintain color in things like canned seafood or frozen potato products like hashbrowns.


SAPP Sodium Acid Pyrophosphate is used Baking Powder, Cake Mixes, Cupcakes, Doughnuts, Leavening Agent, and Refrigerated Dough.
SAPP Sodium Acid Pyrophosphate is usually used in food processing industry.
SAPP Sodium Acid Pyrophosphate can be used as baking powder, the fermentation speed can be fast or slow based on different uses.


SAPP Sodium Acid Pyrophosphate can control fermentation speed and increase production intensity in baking products.
For instant noodles, SAPP Sodium Acid Pyrophosphate can reduce the rehydration time of finished products, and make it not sticky.
For biscuits and pastries, SAPP Sodium Acid Pyrophosphate can shorten the fermentation time, reduce products damage rate, make the loose gap neat, as well as extend the storage period.


For meat and aquatic products processing, SAPP Sodium Acid Pyrophosphate can be used as quality improver.
Food additive: SAPP Sodium Acid Pyrophosphate can be used as a food additive to adjust pH, stabilize pH value, and play a role in preserving freshness and protecting food quality.


Metal surface treatment: SAPP Sodium Acid Pyrophosphate can be used as a metal surface treatment agent to remove oxides and rust, thereby improving the adhesion of the metal surface.
In the food industry as a rapid starter culture, quality improver, SAPP Sodium Acid Pyrophosphate is used for bread, pastries and other synthetic leavening agents of acid components.


With other phosphate compound, SAPP Sodium Acid Pyrophosphate can be used for lunch meat, cooked ham, canned meat and other meat products, such as water retention agents, instant noodle rehydration agents.
SAPP Sodium Acid Pyrophosphate is used as a starter, for baking food and controlling the fermentation speed.


SAPP Sodium Acid Pyrophosphate is used for instant noodles to reduce the rehydration time of finished products, and it is not sticky or rotten.
SAPP Sodium Acid Pyrophosphate can be used for biscuits and cakes, shorten the fermentation time, reduce the product damage rate, loosen and tidy the pores, and prolong the storage period.


Canned seafood: Struvite crystal is occasionally found in canned seafood, and SAPP Sodium Acid Pyrophosphate is used to inhibit its formation, such as in canned tuna.
Chemical analysis: SAPP Sodium Acid Pyrophosphate can be used as a buffer and reagent in chemical analysis.


As a starter, SAPP Sodium Acid Pyrophosphate is used for baking food, controlling fermentation speed, for instant noodles, reducing rehydration time of finished products, and not sticking to it.
SAPP Sodium Acid Pyrophosphate is used for biscuits and pastry, shortening fermentation time, reducing product breakage rate, loose and neat space, and prolonging storage period.


Generally, SAPP Sodium Acid Pyrophosphate is used as an acid component in baking powder; as a chelating agent or combines with other polyphosphates to sequester magnesium and iron ions, e.g. chelate iron during the processing of potatoes to prevent a dark discoloration.
In the bakery, SAPP Sodium Acid Pyrophosphate is a slow leavening acid and it may contain a suitable aluminum and/or calcium salt to control the rate of reaction.


SAPP Sodium Acid Pyrophosphate is used bakery, Canned SeaFood, and Potato Products
SAPP Sodium Acid Pyrophosphate is used together with baking powder as a leavening agent to release carbon dioxide.
SAPP Sodium Acid Pyrophosphate is ideal for refrigerated doughs, cakes, muffins and pancake mixes where a slow reaction rate is desired.


SAPP Sodium Acid Pyrophosphate is often used with fast-acting leavenings such as monocalcium phosphate in double-acting baking powder or sometimes added with another slow action leavening acid, GDL.
SAPP Sodium Acid Pyrophosphate is commonly used as a leavening agent and is an important component of baking powder as well as flour itself.


Yeasts add air and volume to the baked product structure by reacting with baking soda to produce carbon dioxide gas and also change dough characteristics by creating ionic bonds with starches and dough proteins.
SAPP Sodium Acid Pyrophosphate can be used as a leavening chemical to help bread rise.


Frozen raw dough used in biscuits and bread products uses slow acidic SAPP Sodium Acid Pyrophosphate, which requires the release of carbon dioxide at a slower starting rate during preparation and packaging, and a large release of gas during baking.
Low gas rate means that SAPP Sodium Acid Pyrophosphate and sodium bicarbonate emit no more than 22% of the total carbon dioxide in 8 minutes.


SAPP Sodium Acid Pyrophosphate is used in the food industry as a raising agent for flat baked goods, such as cookies and crackers.
SAPP Sodium Acid Pyrophosphate is in China in steamed buns and Chinese almond cookies.
In China SAPP Sodium Acid Pyrophosphate is called edible or food-grade "smelly powder".


SAPP Sodium Acid Pyrophosphate is commonly used as an inexpensive nitrogen fertilizer in China
SAPP Sodium Acid Pyrophosphate is now being phased out in favor of urea for quality and stability.
SAPP Sodium Acid Pyrophosphate is also a basic fertilizer being a source of ammonia


SAPP Sodium Acid Pyrophosphate is used in food processing, as in canned seafood, cured meat and potato products, for adjust the pH, maintain color, improve the water-holding capacity and reduce purge during retorting
Sodium pyrophosphate is used as a fast fermentation agent, quality improver, puffer, buffer, etc. in food processing, and is often used as an acidic ingredient in synthetic puffing agents such as bread and pastries.


SAPP Sodium Acid Pyrophosphate is used in sausages to increase flavor and color.
In French fries, SAPP Sodium Acid Pyrophosphate reduces levels of a carcinogen called acrylamide, according to an article from the Center for Science in the Public Interest.


SAPP Sodium Acid Pyrophosphate also prevents the discoloration of potatoes and sugar syrup and the formation of harmless struvite crystals in canned tuna.
SAPP Sodium Acid Pyrophosphate can also be used in leather treatment.
SAPP Sodium Acid Pyrophosphate is used in some dairy applications for cleaning purposes as well as in the oil production industry.


SAPP Sodium Acid Pyrophosphate may be used as leavening acid which combines with baking soda to release carbon dioxide to improve the texture and volume of baked goods.
SAPP Sodium Acid Pyrophosphate is used as a chelating agent to chelate iron to prevent discoloration in processed potato.


SAPP Sodium Acid Pyrophosphate is used bread, cakes, bread and other foods are characterized by spongy porous tissue to create a soft taste.
In order to achieve this, a sufficient amount of gas must be kept in the dough.
The water vapor produced by the heating of the air and moisture in the material mixture during baking can cause the product to produce some spongy tissue, but the amount of gas is far from enough.


The vast majority of the gas required is provided by puffing agents.
SAPP Sodium Acid Pyrophosphate is used for instant noodles to shorten the rehydration time of the finished product, so that instant noodles won’t be sticky or rotten.


SAPP Sodium Acid Pyrophosphate is used in sausages to enhance flavor and color.
SAPP Sodium Acid Pyrophosphate is used in biscuits and cakes, it can shorten the fermentation time, reduce the product breakage rate, loosen the gaps neatly, and prolong the storage period.


SAPP Sodium Acid Pyrophosphate is used as a quality improver for bakery foods such as bread, biscuits, meat and aquatic products, etc.
SAPP Sodium Acid Pyrophosphate can improve the complex metal ions, PH value and ionic strength of foods, thereby improving the adhesion and water holding capacity of foods,


In French Fries, SAPP Sodium Acid Pyrophosphate can reduce levels of a carcinogen called acrylamide.
SAPP Sodium Acid Pyrophosphate can also prevent discoloration of potatoes and syrup.
In canned tuna, SAPP Sodium Acid Pyrophosphate can prevent the formation of harmless struvite crystals.


In canned seafood, SAPP Sodium Acid Pyrophosphate can retain color during cooking and reduce cleaning.
SAPP Sodium Acid Pyrophosphate is commonly used compound puffer is a carbon dioxide gas produced by the action of sodium bicarbonate and acidic salts.
SAPP Sodium Acid Pyrophosphate is used as buffer, leaven, quality modifier, ferment agent, emulsifier, nutriment, adhesive and preservative in foods.


In food processing industry, SAPP Sodium Acid Pyrophosphate is used as buffering, swelling agent, chelating agent, stabilizers, emulsifier and color improver.
SAPP Sodium Acid Pyrophosphate is used as baking powder in baking food to control the degree of fermentation and improve the production intensity.


For industry, SAPP Sodium Acid Pyrophosphate is applied to oil area as a drilling fluid.
SAPP Sodium Acid Pyrophosphate is used in leather treatment to remove iron stains
SAPP Sodium Acid Pyrophosphate is widely used globally in food industry for baking reaction purpose


SAPP Sodium Acid Pyrophosphate is also used to stabilize the solution of hydrogen peroxide against reduction
SAPP Sodium Acid Pyrophosphate is used in petroleum industry as a dispersant in oil well drilling muds
SAPP Sodium Acid Pyrophosphate also has a wide use in dairy and poultry processes.


Because the resulting phosphate residue has an off-taste, SAPP Sodium Acid Pyrophosphate is usually used in very sweet cakes which mask the taste.
SAPP Sodium Acid Pyrophosphate is designated in the USA as generally recognized as safe for food use.
In cured meats, SAPP Sodium Acid Pyrophosphate accelerates the conversion of sodium nitrite to nitrite by forming a nitrous acid intermediate and can improve water retention.


SAPP Sodium Acid Pyrophosphate is used in frozen hash browns and other potato products to prevent potatoes from darkening.
SAPP Sodium Acid Pyrophosphate may leave a slightly bitter aftertaste in some products, but adding calcium ions, sugar, or flavoring can mask the taste.
SAPP Sodium Acid Pyrophosphate is mainly used in the bakery industry at a leavening agent.


SAPP Sodium Acid Pyrophosphate may also be blended with other phosphates and used for water retention in processed meats, and used to maintain the appearance and texture of uncooked fruits and vegetables.
SAPP Sodium Acid Pyrophosphate is a white, water-soluble solid, commonly used as a buffer and chelating agent and has many applications in food processing industry.


SAPP Sodium Acid Pyrophosphate is used as an acidulant, buffering agent, and leavening agent.
SAPP Sodium Acid Pyrophosphate is developed specifically for use in canned, refrigerated biscuit doughs.
The CO2 release is extremely low - enabling doughs to be held for long periods, even at above normal temperatures.


SAPP Sodium Acid Pyrophosphate is used as a leavening agent in doughnuts, cakes and other prepared mixes.
SAPP Sodium Acid Pyrophosphate is used in canned seafood to maintain color and reduce purge during retorting.
Retorting achieves microbial stability with heat.


SAPP Sodium Acid Pyrophosphate is an acid source for reaction with baking soda to leaven baked goods.
In baking powdeer, SAPP Sodium Acid Pyrophosphate is often labeled as food additive E450.
In cured meats, SAPP Sodium Acid Pyrophosphate speeds the conversion of sodium nitrite to nitrite by forming the nitrous acid intermediate, and can improve water-holding capacity.


Frequently used with slower-acting SAPP Sodium Acid Pyrophosphate to increase reaction rates.
SAPP Sodium Acid Pyrophosphate uses in food: Pies, Ice Creams, Puddings, Frozen Cakes, Pie Tops, Snacks, Muesli Bars, Fruit Twists, Fillings, Bases & Toppings, Instant Puddings, Self Saucing Puddings, Cake Mixes, Pancake Mixes, Muffin Mixes, Cookie Mixes, Cupcake Mixes, Baking Mixes, Instant Pasta & Sauces, Instant Soups, Waffles, Cookies.


SAPP Sodium Acid Pyrophosphate is a buffering and chelating agent used in canned seafood, as a scald agent in poultry and pork, as a sequesterant in potato products, and is used to aid leavening in baked goods.
In leather treatment SAPP Sodium Acid Pyrophosphate can be used to remove iron stains on hides during processing.


SAPP Sodium Acid Pyrophosphate can stabilize hydrogen peroxide solutions against oxidation.
SAPP Sodium Acid Pyrophosphate can be used for cleaning with sulphamic acid in some dairy applications.
In Petroleum production, SAPP Sodium Acid Pyrophosphate can be used as a dispersant in oil well drilling muds.


In leather treatment, SAPP Sodium Acid Pyrophosphate can be used to remove iron stains on hides during processing.
SAPP Sodium Acid Pyrophosphate can be used with sulfamic acid in some dairy applications for cleaning, especially to remove soapstone.
SAPP Sodium Acid Pyrophosphate is also found in browns (frozen) to keep the color of the potatoes from fading.


SAPP Sodium Acid Pyrophosphate is used as a slow reacting aerator acidulant in conjunction with sodium bicarbonate.
SAPP Sodium Acid Pyrophosphate is used in cakes, a part of the gas is generated in the early stage, and a part of the gas is generated after heating in the later stage.


If there is too much gas in the early stage of baking, the volume will expand rapidly.
At this time, the cake tissue has not yet condensed, and the finished product is easy to collapse and the tissue is thicker, but it cannot continue to expand in the later stage.


If using too much slow-speed SAPP Sodium Acid Pyrophosphate, the initial expansion will be slow, and after the product is condensed, part of the baking powder has not yet produced gas, making the cake small in size and losing the meaning of swelling.
The baking powder used for steamed buns and steamed buns needs to produce gas a little faster because the dough is relatively hard.


As a leavening agent, SAPP Sodium Acid Pyrophosphate is applied to roast foodstuffs to control the fermentation speed.
When applied to crackers or cakes, SAPP Sodium Acid Pyrophosphate may shorten fermentation time,lower the breakage, make the porous space in good order and therefore lengthen the shelf life.


SAPP Sodium Acid Pyrophosphate is used in canned seafood to maintain color and reduce purge during retorting.
Retorting achieves microbial stability with heat.
SAPP Sodium Acid Pyrophosphate is used as a leavening agent, reducing zymosis time and can also be used as a water retention agent, and a quality improver for meat and sea food processing.


When added to scalding water, SAPP Sodium Acid Pyrophosphate facilitates removal of hair and scurf in hog slaughter and feathers and scurf in poultry slaughter.
SAPP Sodium Acid Pyrophosphate in petroleum production, it can be used as a dispersant in oil well drilling muds.


SAPP Sodium Acid Pyrophosphate can also be found in frozen hash browns and other potato products, where it is used to keep the color of the potatoes from darkening.
SAPP Sodium Acid Pyrophosphate is used as fast starter, water retention agent, quality improver, used in bread, biscuits and other baked food and meat, aquatic products, etc


SAPP Sodium Acid Pyrophosphate enhances texture, leavening, and stability in a variety of food and industrial applications.
Meticulously formulated and rigorously tested, SAPP Sodium Acid Pyrophosphate offers unparalleled quality, reliability, and performance, making it the preferred choice for professionals and industries worldwide.


SAPP Sodium Acid Pyrophosphate is an anhydrous white powdered material, which complies with the specifications of the current Food Chemicals Codex for Sodium Acid Pyrophosphate.
When applied to instant noodles, SAPP Sodium Acid Pyrophosphate can shorten water resetting time and avoid stickiness and mushiness of the noodles.


When applied to crackers or cakes, SAPP Sodium Acid Pyrophosphate may shorten fermentation time, lower the breakage, make the porous space in good order and therefore lengthen the shelf life.
SAPP Sodium Acid Pyrophosphate is widely used in food processing; in the E number scheme, they are collectively designated as E450, with the disodium form designated as E450(a).


In the United States, SAPP Sodium Acid Pyrophosphate is classified as generally recognized as safe (GRAS) for food use.
In canned seafood, SAPP Sodium Acid Pyrophosphate is used to maintain color and reduce purge during retorting.
Retorting achieves microbial stability with heat.


SAPP Sodium Acid Pyrophosphate is an acid source for reaction with baking soda to leaven baked goods.
In baking powder, SAPP Sodium Acid Pyrophosphate is often labeled as food additive E450.
In cured meats, SAPP Sodium Acid Pyrophosphate speeds the conversion of sodium nitrite to nitrite (NO−2) by forming the nitrous acid (HONO) intermediate, and can improve water-holding capacity.


SAPP Sodium Acid Pyrophosphate is also found in frozen hash browns and other potato products, where it is used to keep the color of the potatoes from darkening.
SAPP Sodium Acid Pyrophosphate is used as a leavening acid in commercial baking powder.


SAPP Sodium Acid Pyrophosphate is used creating a buffing system in the dough provides a pH of 7.3-7.5 that affects the color of the cooked product.
SAPP Sodium Acid Pyrophosphate is used as an acidulant, buffering agent, and leavening agent.
SAPP Sodium Acid Pyrophosphate is used as an acidulant, buffering agent, and leavening agent.


SAPP Sodium Acid Pyrophosphate has a dough reaction rate of 34 - 38.
SAPP Sodium Acid Pyrophosphate is a fast acting leavening phosphate typically used in bakery applications such as cake doughnuts mixes, cake mixes, breadings, and batters.


SAPP Sodium Acid Pyrophosphate is used as a leavening agent, reducing zymosis time and can also be used as a water retention agent, and a quality improver for meat and sea food processing.
SAPP Sodium Acid Pyrophosphate is used strengthen the feed nutrition .


SAPP Sodium Acid Pyrophosphate is used as an acidulant, buffering agent, and leavening agent.
SAPP Sodium Acid Pyrophosphate is used as a leavening agent, reducing zymosis time.
SAPP Sodium Acid Pyrophosphate can also be used as a water retention agent, and a quality improver for meat and sea food processing.


As SAPP Sodium Acid Pyrophosphate acts slowly and does not react quickly with sodium bicarbonate, it is the most common acid used for baking flour products.
In addition to flour and bakery products, SAPP Sodium Acid Pyrophosphate is used in the production of biscuits, doughnut, pancakes, cakes, and baking powders


As SAPP Sodium Acid Pyrophosphate can have a slightly bitter taste, it is important to use sufficient baking soda in the formulation of products such as cakes.
SAPP Sodium Acid Pyrophosphate is used as a separating agent in processed potatoes (It reduces carcinogenic chemicals called acrylamide in fried potatoes)


SAPP Sodium Acid Pyrophosphate prevents color change in potatoes and sugar syrups.
SAPP Sodium Acid Pyrophosphate prevents the formation of steroid crystals in canned fish tones.
SAPP Sodium Acid Pyrophosphate is used as an acidulant, buffering agent, and leavening agent.


SAPP Sodium Acid Pyrophosphate has a dough reaction rate of 24 – 28.
SAPP Sodium Acid Pyrophosphate is an all-purpose phosphate commonly used in prepared mixes, commercial baking powders, and cake doughnut mixes.
SAPP Sodium Acid Pyrophosphate is used in food mainly for its two properties.


SAPP Sodium Acid Pyrophosphate is used as a leavening acid which combines with baking soda to release carbon dioxide to improve the texture and volume of baked goods.
SAPP Sodium Acid Pyrophosphate is used as a chelating agent to chelate iron to prevent discoloration in processed potato.


SAPP Sodium Acid Pyrophosphate is used Leavening agent for bakery products, pH control in processed foods, Buffering agent, Emulsifier, and Nutrient.
In the food industry, SAPP Sodium Acid Pyrophosphate is used as a buffer, leavening agent, chelating agent, stabilizer, emulsifier and color improver.
Canned food: SAPP Sodium Acid Pyrophosphate is used buffering agent.


Ham: SAPP Sodium Acid Pyrophosphate is used leavening agent
Meat: SAPP Sodium Acid Pyrophosphate is used sequestrant agent
As a food-grade additive, SAPP Sodium Acid Pyrophosphate helps control the pH levels in processed foods and is essential in the leavening of bakery products.


SAPP Sodium Acid Pyrophosphate reacts with baking soda to release carbon dioxide, which helps dough rise.
This property is especially valuable in products like cakes, pancakes, and biscuits.
Additionally, SAPP Sodium Acid Pyrophosphate can be used as a buffer, emulsifier, and nutrient in various food applications.


SAPP Sodium Acid Pyrophosphate is a white, water-soluble solid that serves as a leavening agent, buffering and chelating agent, with many applications in the food industry.
SAPP Sodium Acid Pyrophosphate is used as a leavening agent in bakery products; seafood canning and in potato treatment.


As a leavening agent, SAPP Sodium Acid Pyrophosphate is applied to roast foodstuffs to control the fermentation speed.
When applied to instant noodles, SAPP Sodium Acid Pyrophosphate can shorten water resetting time and avoid stickiness and mushiness of the noodles.


SAPP Sodium Acid Pyrophosphate is a chemical compound that has various applications in the food industry where one of the most common is being used as a leavening agent.
Moreover, SAPP Sodium Acid Pyrophosphate is also best used as an acidulant, emulsifier, buffering agent, and as a sequestrant.


-Food uses:
SAPP Sodium Acid Pyrophosphate is a popular leavening agent found in baking powders.
SAPP Sodium Acid Pyrophosphate combines with sodium bicarbonate to release carbon dioxide:

Na2H2P2O7 + NaHCO3 → Na3HP2O7 + CO2 + H2O
SAPP Sodium Acid Pyrophosphate is available in a variety of grades that affect the speed of its action.
Because the resulting phosphate residue has an off-taste, SAPP Sodium Acid Pyrophosphate is usually used in very sweet cakes which mask the off-taste.


-The cake class uses medium-speed type SAPP Sodium Acid Pyrophosphate, which produces a part of the gas in the early stage and then produces a part of the gas after heating.

If the initial baking gas production is too much, the volume is rapidly puffed, at this time the cake tissue has not condensed, the finished product is prone to collapse and the organization is thicker, and the latter can not continue to puff;

The fermentation used in the buns and buns, due to the relatively hard dough, needs to produce gas slightly faster, if the condensation after the production of gas too much, the finished product will appear "flowering" phenomenon.


-Potato products:
SAPP Sodium Acid Pyrophosphate can be used to replace sulfur dioxide, sulfites and bisulfites to maintain the appearance and texture of cooked potato products.

The application of SAPP Sodium Acid Pyrophosphate reduces the dark color from after-cooking darkening in cooked and processed potato products, such as in oil-blanched french fries and potato salad.

It is the naturally present or equipment iron that generates “after cooking darkening” in potatoes.
SAPP Sodium Acid Pyrophosphate stabilizes the color of potatoes and prevents the iron complex from forming a dark pigment due to its strong sequestering properties.



BENEFITS OF SAPP SODIUM ACID PYROPHOSPHATE:
*Non- aluminum.
*White free-flowing crystalline powder.
*Would hydrolyze to sodium orthophosphate if exposed to environment.
*Excellent leavening acid.
*SAPP Sodium Acid Pyrophosphate is made of thermal process phosphoric acid, will release more CO2 rapidly.
*SAPP Sodium Acid Pyrophosphate has no bitter taste and a good smell.



SOLUBILITY OF SAPP SODIUM ACID PYROPHOSPHATE:
10g/100ml, 20°C in water.
The PH value of 1% solution of SAPP Sodium Acid Pyrophosphate is 4-4.5.
SAPP Sodium Acid Pyrophosphate is insoluble in ethanol.



PROPERTIES OF SAPP SODIUM ACID PYROPHOSPHATE:
SAPP Sodium Acid Pyrophosphate is a white powder, relative density of 1.86.
SAPP Sodium Acid Pyrophosphate is soluble in water and insoluble in ethanol.
If its aqueous solution is heated together with diluted inorganic acid, SAPP Sodium Acid Pyrophosphate will be hydrolyzed into phosphoric acid.

SAPP Sodium Acid Pyrophosphate is hydroscopic,and when absorbing humidity it will become into a product with hexa-hydrates.
If SAPP Sodium Acid Pyrophosphate is heated at a temperature above 220℃.
SAPP Sodium Acid Pyrophosphate will decomposed into sodium meta phosphate.



IS SAPP SODIUM ACID PYROPHOSPHATE SAFE IN FOOD:
Studies have shown that people over the age of 18 are recommended to consume 700mg of phosphorus per day.
This intake can supply enough phosphorus for the formation of healthy bones and the processing of cellular energy.
Excessive amounts may lead to loss of bone mineral density and the ability to fully absorb dietary calcium.

Excessive phosphate intake may cause hyperphosphatemia, leading to hypocalcemia or other serious electrolyte imbalances.
Therefore, pyrophosphoric acid can’t be used in excess in food processing.
Since SAPP Sodium Acid Pyrophosphate or other phosphate food additives are dispersed in the prepared food in a standard amount, the intake of phosphorus is difficult to exceed the standard dose required by the human body.



IS SAPP SODIUM ACID PYROPHOSPHATE SAFE USED IN FOOD?
Sodium pyrophosphate or SAPP Sodium Acid Pyrophosphate are edible phosphates, which are helpful for baking and fermentation, such as baking powder.
SAPP Sodium Acid Pyrophosphate can help prevent food from discoloration, such as, used for peeled potatoes.

SAPP Sodium Acid Pyrophosphate is a component of baking powder, naturally fermented flour and corn flour.
Commercially, SAPP Sodium Acid Pyrophosphate is used as an ingredient for pre-made cakes, puddings, waffles, pancakes and muffins.
SAPP Sodium Acid Pyrophosphate can also be added to frozen dough products, flavored milk, bacon, potato products and canned fish.



PROPERTIES OF SAPP SODIUM ACID PYROPHOSPHATE:
*SAPP Sodium Acid Pyrophosphate is a white powder;
*Relative density of SAPP Sodium Acid Pyrophosphate is 1.86;
*SAPP Sodium Acid Pyrophosphate is soluble in water and insoluble in ethanol;
*If its aqueous solution is heated together with diluted inorganic acid, SAPP Sodium Acid Pyrophosphate will be hydrolyzed into phosphoric acid;
*SAPP Sodium Acid Pyrophosphate is hydroscopic, and when absorbing humidity it will become into a product with hexa-hydrates;
*If SAPP Sodium Acid Pyrophosphate is heated at a temperature above 220°C, it will be decomposed into sodium meta phosphate.



FUNCTIONS OF SAPP SODIUM ACID PYROPHOSPHATE:
At first, when the moisture is added to form dough, SAPP Sodium Acid Pyrophosphate reacts with sodium bicarbonate to produce carbon dioxide gas.
Also, pyrophosphate during reaction with sodium bicarbonate creates ionic bounds with starch and protein of dough.

SAPP Sodium Acid Pyrophosphate also dissolves readily to provide anion, anionic pyrophosphate, which interferes with proteins in a well-cooked system to create a moist tissue.
SAPP Sodium Acid Pyrophosphate regulates the reaction rate at the desired level with using specific production techniques.



ADVANTAGES OF SAPP SODIUM ACID PYROPHOSPHATE:
•SAPP Sodium Acid Pyrophosphate acts as a general buffer and acidifying agent in cleaning formulations.
•SAPP Sodium Acid Pyrophosphate is used for stabilization of Hydrogen peroxide solution.
•SAPP Sodium Acid Pyrophosphate is used to remove iron stains during leather tanning.
•SAPP Sodium Acid Pyrophosphate can be used to furnish acidity to product reactions and its specific slow acting properties are extremely valuable in commercial baking powder.
•SAPP Sodium Acid Pyrophosphate is also used in electroplating and slurry thinning



NUTRITIONAL VALUE OF SAPP SODIUM ACID PYROPHOSPHATE:
21g of sodium and 28g of phosphorus are available in 100g of SAPP Sodium Acid Pyrophosphate.
FDA regulations
In the United States, SAPP Sodium Acid Pyrophosphate has been approved as a versatile food ingredient commonly known as Safe Food (GRAS).



HOW IS SAPP SODIUM ACID PYROPHOSPHATE MADE?
SAPP Sodium Acid Pyrophosphate is a condensed phosphate, commonly synthesized by the neutralization of phosphoric acid with sodium hydroxide or sodium carbonate at the ratio of 1:1 to produce monosodium phosphate (NaH2PO4), and then heated approximately 250°C to remove the water.
2 NaH2PO4 → Na2H2P2O7 + H2O



PROPERTIES OF SAPP SODIUM ACID PYROPHOSPHATE:
SAPP Sodium Acid Pyrophosphate is a white free-flowing crystalline powder or granular.
SAPP Sodium Acid Pyrophosphate would hydrolyze to sodium orthophosphate if exposed to the environment.



CHARACTER OF SAPP SODIUM ACID PYROPHOSPHATE:
SAPP Sodium Acid Pyrophosphate is white monoclinic system crystalline powder or fused mass.
SAPP Sodium Acid Pyrophosphate has accessibility, easily soluble in water, insoluble in ethanol.



PHYSICAL AND CHEMICAL PROPERTIES OF SAPP SODIUM ACID PYROPHOSPHATE:
SAPP Sodium Acid Pyrophosphate is a white monoclinic crystalline powder or molten solid.
The relative density of SAPP Sodium Acid Pyrophosphate was 1.86.
SAPP Sodium Acid Pyrophosphate is soluble in water, insoluble in ethanol.

The aqueous solution of SAPP Sodium Acid Pyrophosphate is hydrolyzed to phosphoric acid by heating with dilute inorganic acid.
SAPP Sodium Acid Pyrophosphate is slightly hygroscopic and forms six crystalline hydrates after water absorption.
Sodium metaphosphate is decomposed when heated above 220 °c.
Aluminum and/or calcium salts may be included in appropriate amounts to control the rate of reaction when used as a bulking agent.



PHYSICAL and CHEMICAL PROPERTIES of SAPP SODIUM ACID PYROPHOSPHATE:
CAS: 7758-16-9
EINECS: 231-835-0
InChI: InChI=1/2Na.H4O7P2/c;;1-8(2,3)7-9(4,5)6/h;;(H2,1,2,3)(H2,4,5,6)/q2*+1;/p-4
Molecular Formula: H2Na2O7P2
Molar Mass: 221.94
Density: (hexahydrate) 1.86
Melting Point: decomposes 220℃ [MER06]
Water Solubility: Fully miscible in water. Insoluble in alcohol and ammonia.
Solubility: H2O: 0.1M at 20°C, clear, colorless
Vapor Pressure: 0 Pa at 20℃
Appearance: white powder
Color: White to Off-White
Maximum wavelength (λmax): ['λ: 260 nm Amax: 0.11', 'λ: 280 nm Amax: 0.09']

Merck: 13,8643
PH: 3.5-4.5 (20℃, 0.1M in H2O, freshly prepared)
Storage Condition: -70°C
Stability: Stable
CAS Number: 68915-31-1
PubChem: 24451
EC Number: 231-835-0
Chemical Formula: Na2H2P2O7
Appearance Format: Powder
Color: White
Odor: Odorless
PH value at 20 ° C (10 g / l): 4,0 - 4,7

Melting point / Melting range: 220 ° C
Density at 20 ° C: 1.1 g / cm³
Soluble in water with solubility solubility.
Chemical formula: Na2H2P2O7
Molecular Weight: 221.94
White crystalline powder or granules
Soluble in water
Appearance: White powder or granule
Assay (Na2H2P2O7) %: ≥95
Arsenic (As) %: ≤0.0003
Lead (Pb) %: ≤0.0002
Fluoride (F) %: ≤0.001
pH (1% sol.): 3.5-4.5

Water insoluble %: ≤0.1
Loss on ignition %: ≤0.5
Chemical formula: Na2H2P2O7
Molar mass: 221.936 g•mol−1
Appearance: White odorless powder
Density: 2.31 g/cm3
Melting point: > 600 °C
Solubility in water: 11.9 g/(100 mL) (20 °C)
Refractive index (nD): 1.4645 (hexahydrate)
Hazards:
Flash point: Non-flammable
Formula: Na2H2P2O7
Molecular weight: 221.94

CAS No.: 7758-16-9
EINCS No.: 231-835-0
EEC Classification: E 450(i)
Appearance: White fine powder.
Shelf life: 24 months in original package, under dry and cool storage conditions.
Maximum stack height: 18 months in original package, under dry and cool storage conditions.
Synonyms: Disodium Dihydrogen Pyrophosphate
Chemical Formula: Na2H2P2O7
CAS number: 7758-16-9
Density: 2.31 g/cm³
Molecular Weight: 221.94 g/mol
Appearance: Fine powder
Storage Condition: Store in a cool, dry place away from direct sunlight.



FIRST AID MEASURES of SAPP SODIUM ACID PYROPHOSPHATE:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of SAPP SODIUM ACID PYROPHOSPHATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of SAPP SODIUM ACID PYROPHOSPHATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of SAPP SODIUM ACID PYROPHOSPHATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of SAPP SODIUM ACID PYROPHOSPHATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of SAPP SODIUM ACID PYROPHOSPHATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available