Other Industries

ETHYL HEXANOIC ACID
Ethyl hexanoic acid is the organic compound with the formula CH3(CH2)3CH(C2H5)CO2H.
Ethyl hexanoic acid is a carboxylic acid that is widely used to prepare lipophilic metal derivatives that are soluble in nonpolar organic solvents.
Ethyl hexanoic acid is a colorless viscous oil.

CAS: 149-57-5
MF: C8H16O2
MW: 144.21
EINECS: 205-743-6

Ethyl hexanoic acid is supplied as a racemic mixture.
Ethyl hexanoic acid forms compounds with metal cations that have stoichiometry as metal acetates.
These ethylhexanoate complexes are used in organic and industrial chemical synthesis.
They function as catalysts in polymerizations as well as for oxidation reactions as "oil drying agents."
They are highly soluble in nonpolar solvents.
These metal complexes are often described as salts.
They are, however, not ionic but charge-neutral coordination complexes.
Their structures are akin to the corresponding acetates.

Ethyl hexanoic acid is a colorless to light yellow liquid with a mild odor.
Ethyl hexanoic acid will burn though 2-Ethylhexanoic acid may take some effort to ignite. Ethyl hexanoic acid is slightly soluble in water.
Ethyl hexanoic acid is corrosive to metals and tissue.
Ethyl hexanoic acid is used to make paint dryers and plasticizers.
Ethyl hexanoic acid is a branched-chain fatty acid.

Ethyl hexanoic acid is a colorless to light yellow liquid with a mild odor.
Ethyl hexanoic acid will burn though 2-Ethylhexanoic acid may take some effort to ignite. Ethyl hexanoic acid is slightly soluble in water.
Ethyl hexanoic acid is corrosive to metals and tissue.
Ethyl hexanoic acid is used to make paint dryers and plasticizers.
Ethyl hexanoic acid is a colorless to light yellow liquid with a mild odor.
Ethyl hexanoic acid will burn though it may take some effort to ignite.
Ethyl hexanoic acid is slightly soluble in water.
Ethyl hexanoic acid is corrosive to metals and tissue.
Ethyl hexanoic acid is used to make paint dryers and plasticizers.

Ethyl hexanoic acid, also called 2-EHA, is a commonly used organic compound, mainly to make lipophilic metal by-products that can dissolve in nonionic organic solvents.
Ethyl hexanoic acid is a carboxylic acid with the formula C8H16O2 with a generally high boiling point and mild odor.

Ethyl hexanoic acid is a viscous and colorless oil with one carboxylic class found on a C8 carbon chain and is immiscible in water.
Ethyl hexanoic acid can be used as a substitute for naphthenic acid in some applications.
Industrially, Ethyl hexanoic acid is manufactured using propylene, often generated from fossil fuels and other sources which are renewable.
In other words, Ethyl hexanoic acid can be more effectively manufactured than naphthenic acid.

Ethyl hexanoic acid produces metallic compounds that undergo stoichiometry in the form of metal acetates.
In most cases, Ethyl hexanoic acid derivatives are used in industrial and organic chemical applications.
The ethyl hexanoate complexes also serve as catalysts in oxidation reactions and polymerizations (as oil drying agents).
As a versatile chemical intermediate, Ethyl hexanoic acid has multiple applications, including the following.
Ethyl hexanoic acid is a colorless to light yellow, liquid organic compound.
Ethyl hexanoic acid is widely used in the preparation of metal derivatives that are soluble in nonpolar organic solvents.
The highly toxic, combustible carboxylic acid is used to make paint dryers and plasticizers.

The liquid organic compound has a mild odor, is highly corrosive to metals and tissue, and combustible, but difficult to ignite.
Ethyl hexanoic acid is used in the manufacture of adhesives and sealant chemicals, corrosion inhibitors and anti-scaling agents, intermediates, lubricants and lubricant additives, paint and coating additives, and process regulators.

Ethyl hexanoic acid is a viscosity-increasing agent that is used in the production of high-viscosity polymers.
Ethyl hexanoic acid is a carboxylate salt of ethyl hexanoic acid and zinc.
The reaction of ethylhexane with zirconium oxide produces a viscous liquid with a strong cationic polymerization activity.
Ethyl hexanoic acid reacts with diphenyl ether and aromatic hydrocarbons to form solid products.
The reaction with calcium stearate, an ester of glycerol, results in the formation of particles that are insoluble in water but soluble in organic solvents.
Ethyl hexanoic acid also reacts with ethylene diamine to form methyl myristate, which has kinetic data available for Ethyl hexanoic acid.

Ethyl hexanoic acid Chemical Properties
Melting point: -59 °C
Boiling point: 228 °C(lit.)
Density: 0.906
Vapor density: 4.98 (vs air)
Vapor pressure: Refractive index: n20/D 1.425(lit.)
Fp: 230 °F
Storage temp.: Store below +30°C.
Solubility: 1.4g/l
Form: Liquid
Pka: pK1:4.895 (25°C)
Color: Clear
PH: 3 (1.4g/l, H2O, 20℃)
Odor: Mild odour
PH Range: 3 at 1.4 g/l at 20 °C
Explosive limit: 1.04%, 135°F
Water Solubility: 2 g/L (20 ºC)
BRN: 1750468
Exposure limits ACGIH: TWA 5 mg/m3
Stability: Stable. Combustible. Incompatible with strong oxidizing agents, reducing agents, bases.
InChIKey: OBETXYAYXDNJHR-UHFFFAOYSA-N
LogP: 2.7 at 25℃
CAS DataBase Reference: 149-57-5(CAS DataBase Reference)
NIST Chemistry Reference: Ethyl hexanoic acid(149-57-5)
EPA Substance Registry System: Ethyl hexanoic acid (149-57-5)

Uses
Paint and varnish driers (metallic salts).
Ethylhexoates of light metals are used to convert some mineral oils to greases.
Ethyl hexanoic acid's esters are used as plasticizers.
Ethyl hexanoic acid is used in the preparation of metal derivatives, which act as a catalyst in polymerization reactions.
For example, tin Ethyl hexanoic acid is used in the manufacturing of poly(lactic-co-glycolic acid).
Ethyl hexanoic acid is also used as a stabilizer for polyvinyl chlorides.
Ethyl hexanoic acid is also involved in solvent extraction and dye granulation.
Further, Ethyl hexanoic acid is used to prepare plasticizers, lubricants, detergents, flotation aids, corrosion inhibitors and alkyd resins.
In addition to this, Ethyl hexanoic acid serves as a catalyst for polyurethane foaming.

Ethyl hexanoic acid can be used:
As a reactant in esterification , decarboxylative alkynylation , and preparation of alkyl coumarins via decarboxylative coupling reactions.
In the organocatalytic medium for the preparation of various 3,4-dihydropyrimidin-2(1H)-ones/thiones by Biginelli reaction.

Automotive
Ethyl hexanoic acid is used to produce corrosion inhibitors for lubricants and automotive coolants.
Ethyl hexanoic acid also serves as wood preservatives and makes lubricant additives as well as synthetic lubricants.
Ethyl hexanoic acid is also used in the production of PVC heat stabilizers, PVB film plasticizers, metal soaps for paint driers, and other chemicals.

Lubricants
Ethyl hexanoic acid is commonly used in esters in Polyvinyl butyral (PVB) film plasticizers and as a raw material for polyesters applied in synthetic oils.
Ethyl hexanoic acid’s metal salts are used to prepare synthetic lubricant additives used in various industrial lubricant applications.

Coatings
Ethyl hexanoic acid is widely used in coating applications to enhance performance and resistance.
Ethyl hexanoic acid produces alkyd resins that help improve yellowing resistance better than ordinary fatty acids.
Ethyl hexanoic acid is ideal for stoving enamels and 2-component coatings.
Ethyl hexanoic acid can also be used in other applications, including the catalyst for polyurethane, wood preservatives, and pharmaceuticals.

Cosmetics
The chemicals in Ethyl hexanoic acid are reported to have cosmetic use to produce emollients and skin conditioners.
Ethyl hexanoic acid is widely used in hair care products, hand creams, face creams, body lotions, and make-up products like foundation, concealer, and hair care products.

Plastics
Ethyl hexanoic acid is also used in manufacturing polyvinyl chloride (PVC) stabilizers and Polyvinyl butyral (PVB) plasticizers in the form of metal salts.
Ethyl hexanoic acid reacts with metallic components like manganese and cobalt to produce metallic salt derivatives.

Production
Ethyl hexanoic acid is produced industrially from propylene, which is hydroformylated to give butyraldehyde.
Aldol condensation of the aldehyde gives Ethyl hexanoic acid, which is hydrogenated to 2-ethylhexanal.
Oxidation of this aldehyde gives the carboxylic acid.

Reactivity Profile
Ethyl hexanoic acid is a carboxylic acid.
Carboxylic acids donate hydrogen ions if a base is present to accept them.
They react in this way with all bases, both organic (for example, the amines) and inorganic.
Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat.
Neutralization between an acid and a base produces water plus a salt.
Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water.

Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions.
The pH of solutions of carboxylic acids is therefore less than 7.0.
Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt.
Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt.
Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry.
Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in Ethyl hexanoic acid to corrode or dissolve iron, steel, and aluminum parts and containers.

Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide.
The reaction is slower for dry, solid carboxylic acids.
Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide.
Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides.
Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat.

Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat.
Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents.
These reactions generate heat.
A wide variety of products is possible.
Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions.

Synonyms
2-ETHYLHEXANOIC ACID
149-57-5
2-Ethylcaproic acid
Hexanoic acid, 2-ethyl-
Ethylhexanoic acid
Ethylhexoic acid
2-Ethylhexoic acid
Butylethylacetic acid
2-Butylbutanoic acid
3-Heptanecarboxylic acid
Ethyl hexanoic acid
2-ethyl-hexoic acid
2-ethyl hexanoic acid
alpha-Ethylcaproic acid
2-Ethylhexansaeure
2-ethyl-hexanoic acid
125804-07-1
Ethyl hexanoic acid, 2-
2 ETHYL HEXANOIC ACID
CCRIS 3348
HSDB 5649
alpha-ethyl caproic acid
Kyselina 2-ethylkapronova [Czech]
NSC 8881
Kyselina 2-ethylkapronova
EINECS 205-743-6
.alpha.-Ethylcaproic acid
2-Ethyl-1-hexanoic acid
UNII-01MU2J7VVZ
Kyselina heptan-3-karboxylova [Czech]
BRN 1750468
01MU2J7VVZ
Kyselina heptan-3-karboxylova
AI3-01371
2-ETHYL HEXOIC ACID,AR
61788-37-2
DTXSID9025293
CHEBI:89058
Hexanoic acid, 2-ethyl-, (-)-
NSC-8881
EINECS 262-971-9
2-ethylhexanoicacid
EC 205-743-6
DTXCID805293
2-Ethylhexanoic acid, >=99%
C8H16O2.1/2Cu
2-Ethylhexanoic acid, analytical standard
CAS-149-57-5
(+/-)-2-ETHYLHEXANOIC ACID
Hexanoic acid, 2-ethyl-, copper(2++) salt
MFCD00002675
2-Ethylcapronic acid
2-Ethyl-Hexonic acid
alpha-Ethylhexanoic acid
EHO (CHRIS Code)
.alpha.-Ethylhexanoic acid
SCHEMBL25800
2-Ethylhexanoic acid, 99%
MLS002415695
2-Ethylhexanoic acid, Inhalable
CHEMBL1162485
WLN: QVY4 & 2
NSC8881
HMS2267F21
CS-CY-00011
STR05759
2-ETHYLHEXANOIC ACID [HSDB]
Tox21_201406
Tox21_300108
LMFA01020087
LS-869
AKOS009031416
AT29893
CS-W016381
SB44987
SB44994
Hexanoic acid,2-ethyl-, tridecyl ester
NCGC00091324-01
NCGC00091324-02
NCGC00091324-03
NCGC00253985-01
NCGC00258957-01
SMR001252268
Hexanoic acid, 2- ethyl- , tridecyl ester
E0120
FT-0612273
FT-0654390
EN300-20410
Q209384
Ethyl hexanoic acid, 2-; (Butyl ethyl acetic acid)
W-109079
Azilsartan K Medoxomil Impurity-7 (2-EHA Impurities)
F0001-0703
Z104478072
18FEB650-7573-4EA0-B0CD-9D8BED766547
2-Ethylhexanoic acid, Pharmaceutical Secondary Standard; Certified Reference Material
Ethyl Hexyl Glycerine
Synonyms3-[2-(EthyL;liquid,100Ml;Sensiva SC 50;OCTOXYGLYCERIN;Sensiva SC 50JP;ETHYLHEXYLGLYCERIN;Ethylhexyl Glecerine;Ethyl hexyl glycerol;Glycerol α-(2-Ethylhexyl) Ether;3-(2-ethylhexoxy)propane-1,2-dio CAS No.70445-33-9
ETHYL ISOSTEARATE
ETHYL LINALOOL. N° CAS : 10339-55-6. Nom INCI : ETHYL LINALOOL. Nom chimique : 3,7-Dimethyl-1,6-nonadien-3-ol; Homolinalool. N° EINECS/ELINCS : 233-732-6. Ses fonctions (INCI) : Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit. Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques
ETHYL LACTATE
Ethyl lactate is an environmentally benign solvent with effectiveness comparable to petroleum-based solvents.
Ethyl lactate is found naturally in small quantities in a wide variety of foods including wine, chicken, and various fruits.
Ethyl lactate, also known as lactic acid ethyl ester, is the organic compound with the formula CH3CH(OH)CO2CH2CH3.

CAS Number: 687-47-8
EC Number: 202-598-0
Molecular Formula: C5H10O3
Molecular Weight (g/mol): 118.13

Ethyl lactate is found naturally in small quantities in a wide variety of foods including wine, chicken, and various fruits.
The odor of ethyl lactate when dilute is mild, buttery, creamy, with hints of fruit and coconut.

Ethyl lactate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 to < 100 tonnes per annum.
Ethyl lactate is used by consumers, by professional workers (widespread uses), in formulation or re-packing and at industrial sites.

Ethyl lactate, also known as lactic acid ethyl ester, is the organic compound with the formula CH3CH(OH)CO2CH2CH3.
Ethyl lactate is the ethyl ester of lactic acid.

A colorless liquid, Ethyl lactate is a chiral ester.
Being naturally derived, Ethyl lactate is readily available as a single enantiomer.

Ethyl lactate is commonly used as a solvent.
Ethyl lactate is considered biodegradable and can be used as a water-rinsible degreaser.

Ethyl lactate is an environmentally benign solvent with effectiveness comparable to petroleum-based solvents.
The worldwide solvent market is about 30 million pounds per year, where ethyl lactate can have an important share.

Ethyl lactate is considered a chemical commodity and has attracted much attention in recent years, since Ethyl lactate is formed by the esterification reaction of ethanol and lactic acid, which can be generated from biomass raw materials through fermentation.
In this work, an overview regarding the main properties and applications of ethyl lactate, as well as Ethyl lactate synthesis and production processes, with a particular emphasis on reactive/separation processes, is presented.

Ethyl lactate, lactic acid ethyl ester or 2-hydroxypropanoic acid ethyl ester is the chemical compound of lactic acid with ethanol in the form of an ester.
Depending on Ethyl lactate synthesis, Ethyl lactate is available as racemate or pure substance.

If ethyl lactate is split back into Ethyl lactate starting materials ethanol and lactic acid (e.g. by a chemical reaction), Ethyl lactate can be decomposed in nature.
Esterases, naturally occurring enzymes, can also carry out the split back into the original materials.

Lactic acid ethyl ester is therefore considered a "green solvent", as Ethyl lactate does not leave any toxic decomposition products in the ecosystem.
This provides an advantage over chlorinated solvents or glycols or glycol ethers, which have a higher biological toxicity.

Also known as lactic acid ethyl ester, is a monobasic ester formed from lactic acid and ethanol, commonly used as a solvent hence the name “lactic acid ethyl ester”.
Ethyl lactate is considered biodegradable and can be used as a water-risible degreaser.
Ethyl lactate is found naturally in small quantities in a wide variety of foods including wine, chicken, and various fruits.

Ethyl lactate is produced from biological sources and can be either the Levo (S) form or Dextro (R) form, depending on the organism that is the source of the lactic acid.
The most biologically sourced ethyl lactate is ethyl (−)-L-lactate (ethyl (S)-lactate).

Ethyl lactate is also produced industrially from petrochemical stocks, and this ethyl lactate consists of the racemic mixture of Levo and Dextro forms.
In some jurisdictions, the natural product is exempt from many restrictions placed upon the use and disposal of solvents.
Because both enantiomers are found in nature, and because ethyl lactate is easily biodegradable, Ethyl lactate is considered to be a “green solvent.”

Uses of Ethyl lactate:
Ethyl lactate is used as a solvent substitute for glycol ethers in photolithography in the semiconductor manufacturing industry.
Ethyl lactate is used in some nail polish removers.

Ethyl lactate is used as a solvent for resins, dyes, and coatings; has FDA approval for use as a food flavoring agent
Ethyl lactate is the active ingredient in many anti-acne preparations.

Uses at industrial sites:
Ethyl lactate is used in the following products: semiconductors, photo-chemicals, polymers, metal surface treatment products, non-metal-surface treatment products and washing & cleaning products.
Ethyl lactate is used in the following areas: formulation of mixtures and/or re-packaging.

Ethyl lactate is used for the manufacture of: electrical, electronic and optical equipment and machinery and vehicles.
Release to the environment of Ethyl lactate can occur from industrial use: in processing aids at industrial sites.

Industry Uses:
Processing aids, not otherwise listed
Solvent
Solvents (which become part of product formulation or mixture)

Consumer Uses:
Ethyl lactate is used in the following products: air care products, biocides (e.g. disinfectants, pest control products), perfumes and fragrances, polishes and waxes, washing & cleaning products and cosmetics and personal care products.
Other release to the environment of Ethyl lactate is likely to occur from: indoor use as processing aid and outdoor use as processing aid.

Widespread uses by professional workers:
Ethyl lactate is used in the following products: polishes and waxes and washing & cleaning products.
Other release to the environment of Ethyl lactate is likely to occur from: indoor use as processing aid.

Industrial Processes with risk of exposure:
Semiconductor Manufacturing
Painting (Solvents)
Plastic Composites Manufacturing

Applications of Ethyl lactate:
Ethyl Lactate is an excellent ingredient for formulating printing inks, coatings, resin cleaners, paint strippers, graffiti removers, ink cleaners, etc.
Ethyl lactate alone and is an ideal wipe solvent.

Ethyl lactate can be used in industrial coatings applications, primarily in coil, extrusion, wood furniture and fixtures, containers and closures, automotive finishes and machinery.
Ethyl lactate is 100% biodegradable, easy and inexpensive to recycle.

Due to Ethyl lactate low toxicity, ethyl lactate is a popular choice across many different production scenarios.
Ethyl lactate is also used as a solvent with various types of polymers.
In the presence of water, acids and bases the chemical will hydrolyse into ethanol and lactic acid.

Because both enantiomers are found in nature, and because ethyl lactate is easily biodegradable, Ethyl lactate is considered to be a "green solvent."
Ethyl lactate and Ethyl lactate aqueous solutions are used as sustainable media for organic synthesis.

Due to Ethyl lactate relatively low toxicity, ethyl lactate is used commonly in pharmaceutical preparations, food additives, and fragrances.
Ethyl lactate is also used as solvent for nitrocellulose, cellulose acetate, and cellulose ethers.

Production of Ethyl lactate:
Ethyl lactate is produced from biological sources, and can be either the levo (S) form or dextro (R) form, depending on the organism that is the source of the lactic acid.
Most biologically sourced ethyl lactate is ethyl (−)-L-lactate (ethyl (S)-lactate).
Ethyl lactate is also produced industrially from petrochemical stocks, and this ethyl lactate consists of the racemic mixture of levo and dextro forms.

Methods of Manufacturing of Ethyl lactate:

Derivation: (a) By the esterification of lactic acid with ethanol; (b) by combining acetaldehyde with hydrogen cyanide to form acetaldehyde cyanohydrin, which is converted into ethyl lactate by treating with ethanol and an inorganic acid.

d-Ethyl lactate is obtained from d-lactic acid by azeotropic distillation with ethyl alcohol or benzene in the presence of concentrated H2SO4.
The l-form is prepared in similar fashion starting from l-lactic acid.
The racemic product is prepared by boiling for 24 hours optically inactive lactic acid with ethyl alcohol in carbon tetrachloride, or with an excess of ethyl alcohol in the presence of chlorosulfonic acid, or in the presence of benzenesulfonic acid in benzene solution.

Handling and Storage of Ethyl lactate:

Nonfire Spill Response:
ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.
All equipment used when handling Ethyl lactate must be grounded.

Do not touch or walk through spilled material.
Stop leak if you can do Ethyl lactate without risk.

Prevent entry into waterways, sewers, basements or confined areas.
A vapor-suppressing foam may be used to reduce vapors.

Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers.
Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL:
Dike far ahead of liquid spill for later disposal.
Water spray may reduce vapor, but may not prevent ignition in closed spaces.

Reactivity Profile of Ethyl lactate:

Ethyl lactate is an ester.
Esters react with acids to liberate heat along with alcohols and acids.
Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products.

Heat is also generated by the interaction of esters with caustic solutions.
Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Fire Fighting of Ethyl lactate:
The majority of these products have a very low flash point.
Use of water spray when fighting fire may be inefficient.

SMALL FIRE:
Dry chemical, CO2, water spray or alcohol-resistant foam.
Do not use dry chemical extinguishers to control fires involving nitromethane (UN1261) or nitroethane (UN2842).

LARGE FIRE:
Water spray, fog or alcohol-resistant foam.
Avoid aiming straight or solid streams directly onto Ethyl lactate.
If Ethyl lactate can be done safely, move undamaged containers away from the area around the fire.

FIRE INVOLVING TANKS OR CAR/TRAILER LOADS:
Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.
Cool containers with flooding quantities of water until well after fire is out.

Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
ALWAYS stay away from tanks engulfed in fire.
For massive fire, use unmanned master stream devices or monitor nozzles; if this is impossible, withdraw from area and let fire burn.

Accidental Release Measures of Ethyl lactate:

Isolation and Evacuation:

IMMEDIATE PRECAUTIONARY MEASURE:
Isolate spill or leak area for at least 50 meters (150 feet) in all directions.

LARGE SPILL:
Consider initial downwind evacuation for at least 300 meters (1000 feet).

FIRE:
If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Cleanup Methods:
Use personal protective equipment.
Avoid breathing vapors, mist or gas.

Ensure adquate ventilation.
Remove all sources of ignition.

Evacuate personnel to safe areas.
Beware of vapors accumulating to form explosive concentrations.
Vopors can accumulate in low areas.

Disposal Methods of Ethyl lactate:
Recycle any unused portion of the material for Ethyl lactate approved use or return Ethyl lactate to the manufacturer or supplier.

Ultimate disposal of the chemical must consider:
Ethyl lactate's impact on air quality; potential migration in air, soil or water; effects on animal, aquatic and plant life; and conformance with environmental and public health regulations.
If Ethyl lactate is possible or reasonable use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.

Identifiers of Ethyl lactate:
CAS Number:
687-47-8 (L-isomer)
97-64-3 (racemate)
7699-00-5 (D-isomer)

ChemSpider: 13837423
ECHA InfoCard: 100.002.363
EC Number: 202-598-0
PubChem CID: 7344
RTECS number: OD5075000
UNII: F3P750VW8I
UN number: 1192
CompTox Dashboard (EPA): DTXSID6029127
InChI: InChI=1S/C5H10O3/c1-3-8-5(7)4(2)6/h4,6H,3H2,1-2H3
Key: LZCLXQDLBQLTDK-UHFFFAOYSA-N
InChI=1/C5H10O3/c1-3-8-5(7)4(2)6/h4,6H,3H2,1-2H3
Key: LZCLXQDLBQLTDK-UHFFFAOYAV
SMILES: CCOC(=O)C(C)O

Synonym(s): (S)-(-)-Ethyl lactate, L(-)-Lactic acid ethyl ester, (S)-(-)-2-Hydroxypropionic acid ethyl ester
Linear Formula: CH3CH(OH)COOC2H5
CAS Number: 687-47-8
Molecular Weight: 118.13
MDL number: MFCD00004518
EC Index Number: 211-694-1

CAS: 687-47-8
Molecular Formula: C5H10O3
Molecular Weight (g/mol): 118.13
MDL Number: MFCD00004518
InChI Key: LZCLXQDLBQLTDK-BYPYZUCNSA-N
PubChem CID: 92831
ChEBI: CHEBI:78322
IUPAC Name: ethyl (2S)-2-hydroxypropanoate
SMILES: CCOC(=O)C(C)O

Properties of Ethyl lactate:
Chemical formula: C5H10O3
Molar mass: 118.132 g·mol−1
Appearance: Colorless liquid
Density: 1.03 g/cm3
Melting point: −26 °C (−15 °F; 247 K)
Boiling point: 151 to 155 °C (304 to 311 °F; 424 to 428 K)
Solubility in water: Miscible
Solubility in ethanol
and most alcohols: Miscible
Chiral rotation ([α]D): −11.3°
Magnetic susceptibility (χ): -72.6·10−6 cm3/mol

vapor pressure: 1.6 hPa ( 20 °C)
Quality Level: 200
Assay: ≥99% (GC)
form: liquid
autoignition temp.: 400 °C
potency: >2000 mg/kg LD50, oral (Rat)
expl. lim.: 1.5-16.4 % (v/v)
pH: 4 (20 °C, 50 g/L in H2O)
kinematic viscosity: 2.7 cSt(25 °C)
bp: 154 °C/1013 hPa
mp: -25 °C
transition temp: flash point 53 °C
density: 1.03 g/cm3 at 20 °C
storage temp.: 2-30°C
InChI: 1S/C5H10O3/c1-3-8-5(7)4(2)6/h4,6H,3H2,1-2H3/t4-/m0/s1
InChI key: LZCLXQDLBQLTDK-BYPYZUCNSA-N

Molecular Weight: 118.13 g/mol
XLogP3-AA: 0.2
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 3
Exact Mass:
118.062994177 g/mol
Monoisotopic Mass:
118.062994177 g/mol
Topological Polar Surface Area: 46.5Ų
Heavy Atom Count: 8
Complexity: 79.7
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Ethyl lactate:
Acidity: 0.1% max. (as lactic acid)
Melting Point: -26.0°C
Density: 1.0340g/mL
Boiling Point: 154.0°C
Flash Point: 46°C
Infrared Spectrum: Authentic
Assay Percent Range: 96% min. (GC)
Packaging: Glass bottle
Linear Formula: CH3CH(OH)CO2C2H5
Refractive Index: 1.4100 to 1.4160
Quantity: 250 mL
Beilstein: 03,264
Fieser: 17,135
Merck Index: 14,3817
Specific Gravity: 1.034
Specific Rotation Condition: − 10.00 (20.00°C neat)
Specific Rotation: − 10.00
Solubility Information: Solubility in water: soluble. Other solubilities: miscible with alcohols,ketones and esters
Formula Weight: 118.13
Percent Purity: 97%
Physical Form: Liquid
Chemical Name or Material: Ethyl L(-)-lactate

Structure of Ethyl lactate:
Dipole moment: 3.46 D

Related compounds of Ethyl lactate:
Lactic acid, Methyl lactate

Related Products of Ethyl lactate:
Dimethyl Glutaconate (~10% Cis)
(E,E)-4,6-Dimethyl-2,4-heptadienoic Acid
3,6-Dimethyl-3-heptanol
1,1-Dimethoxybutane
(E)-6,6-Dimethyl-2-hept-1-en-4-yn-1-amine

Names of Ethyl lactate:

Regulatory process names:
2-Hydroxypropanoic acid ethyl ester
Actylol
Acytol
Ethyl 2-hydroxypropionate
Ethyl alpha-hydroxypropionate
ethyl DL-lactate
Ethyl lactate
ETHYL LACTATE
Ethyl lactate
ethyl lactate
Ethyl lactate (natural)
ethyl lactate ethyl DL-lactate
ethyl lactate; ethyl DL-lactate
Ethylester kyseliny mlecne
Lactate d'ethyle
Lactic acid, ethyl ester
Propanoic acid, 2-hydroxy-, ethyl ester
Solactol

Translated names:
DL-mleczan etylu (pl)
ester etylowy kwasu mlekowego (pl)
Ethyl DL-lactat (de)
ethyl-DL-laktát (cs)
ethyl-laktát (cs)
ethyl-laktát ethyl-DL-laktát (cs)
ethyllacta (da)
ethyllactaat (nl)
Ethyllactat (de)
Ethyllactat Ethyl DL-lactat (de)
etil DL-lactat (ro)
etil DL-laktat (sl)
etil lactat (ro)
etil lactat etil DL-lactat (ro)
etil laktat (sl)
etil laktat etil DL-laktat (sl)
etil-DL-laktat (hr)
etil-DL-laktatas (lt)
etil-DL-laktát (hu)
etil-DL-laktāts (lv)
etil-laktat (hr)
etil-laktát (hu)
etil-laktát etil-DL-laktát (hu)
etillaktatas (lt)
etillaktatas etil-DL-laktatas (lt)
etillaktāts (lv)
etyl-(RS)-laktát (sk)
etyl-laktát (sk)
etyllaktat (no)
etyllaktat (sv)
etyylilaktaatti (fi)
Etüül-DL-laktaat (et)
Etüüllaktaat (et)
lactate d'éthyle; DL-lactate d'éthyle; (fr)
lactato de etilo (es)
lactato de etilo (pt)
lattato di etile (it)
mleczan etylu (pl)
mleczan etylu DL-mleczan etylu ester etylowy kwasu mlekowego (pl)
γαλακτικό αιθυλο (el)
етил DL-лактат (bg)
етил лактат (bg)
етил лактат етил DL-лактат (bg)

IUPAC names:
2-ethoxypropanoic acid
ethyl (2R)-2-hydroxypropanoate
Ethyl (S)-2-hydroxypropanoate
ethyl 2-hydroxypropanoat
ETHYL 2-HYDROXYPROPANOATE
Ethyl 2-hydroxypropanoate
ethyl 2-hydroxypropanoate
Ethyl alpha hydroxypropionate
Ethyl DL Lactate
ethyl DL-lactate
ETHYL LACTATE
Ethyl Lactate
Ethyl lactate
ethyl lactate
ethyl lactate
ethyl lactate;
Ethyllactat
Ethyl 2-hydroxypropanoate

Other names:
Ethyl lactate
Lactic acid ethyl ester
2-Hydroxypropanoic acid ethyl ester
Actylol
Acytol

Other identifiers:
2676-33-7
607-129-00-7
97-64-3

Synonyms of Ethyl lactate:
ETHYL LACTATE
97-64-3
Ethyl 2-hydroxypropanoate
Solactol
Actylol
Acytol
Lactic acid, ethyl ester
Ethyl 2-hydroxypropionate
Propanoic acid, 2-hydroxy-, ethyl ester
Lactate d'ethyle
2-Hydroxypropanoic acid ethyl ester
Lactic Acid Ethyl Ester
Ethyl alpha-hydroxypropionate
FEMA No. 2440
Eusolvan
Ethyl lactate (natural)
Ethylester kyseliny mlecne
Lactate d'ethyle [French]
NSC 8850
HSDB 412
Ethylester kyseliny mlecne [Czech]
2-Hydroxypropionic Acid Ethyl Ester
EINECS 202-598-0
UN1192
Ethyl ester of lactic acid
BRN 1209448
UNII-F3P750VW8I
AI3-00395
F3P750VW8I
Ethyl .alpha.-hydroxypropionate
DTXSID6029127
CHEBI:78321
NSC-8850
4-03-00-00643 (Beilstein Handbook Reference)
ethyl d-lactate
Ethyl lactate,C5H10O3,97-64-3
EthylL-(-)-Lactate
ethyl-lactate
ethyl DL-lactate
DL-Ethyl Lactate
Milchsaureathylester
Nat. Ethyl Lactate
MFCD00065359
Ethyl racemic-lactate
lactic acid ethylester
(S)-(-)-2-Hydroxypropionic acid ethyl ester
PURASOLV ELS
VERTECBIO EL
Lactic acid-ethyl ester
ELT (CHRIS Code)
Mono-Ethyl mono-lactate
ETHYL LACTATE [MI]
(.+/-.)-Ethyl lactate
Ethyl 2-hydroxypropanoate #
ETHYL LACTATE [FCC]
SCHEMBL22598
ETHYL LACTATE [FHFI]
ETHYL LACTATE [HSDB]
ETHYL LACTATE [INCI]
ETHYL LACTATE [MART.]
DTXCID509127
WLN: QVY1 & O2
ETHYL LACTATE [WHO-DD]
CHEMBL3186323
(+-)-Ethyl 2-hydroxypropanoate
(+-)-Ethyl 2-hydroxypropionate
FEMA 2440
NSC8850
Tox21_200889
2-hydroxy-propionic acid ethyl ester
NA1192
Ethyl lactate, >=98%, FCC, FG
AKOS009157222
LS-2733
UN 1192
(+/-)-LACTIC ACID ETHYL ESTER
CAS-97-64-3
NCGC00248866-01
NCGC00258443-01
(+/-)-ETHYL 2-HYDROXYPROPIONATE
AS-13500
SY030456
A9137
Ethyl lactate [UN1192] [Flammable liquid]
Ethyl lactate, natural, >=98%, FCC, FG
Ethyl lactate, SAJ first grade, >=97.5%
FT-0626259
FT-0627926
FT-0651151
L0003
Ethyl lactate [UN1192] [Flammable liquid]
EN300-115258
A845735
Q415418
J-521263
2-[(4-benzylpiperazin-1-yl)methyl]isoindoline-1,3-dione
(±)-Ethyl 2-hydroxypropanoate
(±)-Ethyl 2-hydroxypropionate
(±)-Ethyl lactate
2-Hydroxypropanoate d'éthyle [French] [ACD/IUPAC Name]
2-Hydroxypropanoic acid ethyl ester
97-64-3 [RN]
Ethyl 2-hydroxypropanoate [ACD/IUPAC Name]
Ethyl ester of lactic acid
Ethyl lactate [ACD/Index Name] [Wiki]
Ethyl α-hydroxypropionate
Ethyl α-hydroxypropionate
Ethyl-2-hydroxypropanoat [German] [ACD/IUPAC Name]
MFCD00065359 [MDL number]
OD5075000
Propanoic acid, 2-hydroxy-, ethyl ester [ACD/Index Name]
QY1&VO2 [WLN]
2-hydroxypropionic acid ethyl ester
4-03-00-00643 [Beilstein]
Actylol
Acytol
DL-Ethyl Lactate
DL-Ethyllactate
DL-LACTIC ACID, ETHYL ESTER
Ethyl 2-hydroxy propanoate
Ethyl lactate,C5H10O3,97-64-3
Ethyl racemic-lactate
Ethylester kyseliny mlecne [Czech]
ethyllactate
Ethyl-lactate
Eusolvan
Lactate d'ethyle [French]
lactic acid ethyl ester
Lactic acid, ethyl ester
Lactic acid-ethyl ester
L-lactic acid ethyl ester
MFCD00077825 [MDL number]
Milchs??ure??thylester
Propanoic acid, 2-hydroxy-, ethyl ester (9CI)
Solactol
UN 1192
Ethyl Lactate
Lactic acid ethyl ester; 2-Hydroxypropanoic acid, ethyl ester; Ethyllactat (German); Lactato de etilo (Spanish); Lactate d'éthyle (French); CAS NO:97-64-3
Ethyl Lauryl Arginate HCL
Aminat G;Mirenat CF;CytoGuard LA;C20H41ClN4O3;ethyl lauroyl arginate;ETHYL LAUROYL ARGINATE HCL;Lauroyl Arginine Ethyl Ester;Ethyl-Nα-lauroyl-L-arginate.HCl;ETHYLLAUROYLARGINATEHYDROCHLORIDE;Ethyl N-lauroyl-L-arginate hydrochloride CAS No.60372-77-2
ETHYL LINALOOL
ETHYL LINALOOL, N° CAS : 10339-55-6. Nom INCI : ETHYL LINALOOL. Nom chimique : 3,7-Dimethyl-1,6-nonadien-3-ol; Homolinalool. N° EINECS/ELINCS : 233-732-6. Ses fonctions (INCI) : Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit. Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques
ETHYL LINOLENATE
ETHYL LINOLEATE, N° CAS : 544-35-4, Nom INCI : ETHYL LINOLEATE, Nom chimique : Ethyl linoleate, N° EINECS/ELINCS : 208-868-4, Compatible Bio (Référentiel COSMOS), Ses fonctions, (INCI), Emollient : Adoucit et assouplit la peau. Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques
Ethyl linoleate
ETHYL METHACRYLATE, N° CAS : 97-63-2. Nom INCI : ETHYL METHACRYLATE. Nom chimique : Ethyl methacrylate. N° EINECS/ELINCS : 202-597-5. Ses fonctions (INCI) : Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques
ETHYL METHACRYLATE
ETHYL METHOXYCINNAMATE, N° CAS : 99880-64-5. Nom INCI : ETHYL METHOXYCINNAMATE. Nom chimique : Ethyl p-methoxycinnamate. N° EINECS/ELINCS : 217-679-6. Ses fonctions (INCI). Absorbant UV : Protège le produit cosmétique contre les effets de la lumière UV
ETHYL METHOXYCINNAMATE
ETHYL NICOTINATE. N° CAS : 614-18-6. Nom INCI : ETHYL NICOTINATE. Nom chimique : 3-Pyridinecarboxylic acid, ethyl ester. N° EINECS/ELINCS : 210-370-7. Ses fonctions (INCI) : Agent d'entretien de la peau : Maintient la peau en bon état. Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques
Ethyl Methyl Carbonate
Acetic acid, ethyl ester; Ethyl acetic ester; Acetidin; Acetate d'ethyle; Acetato de etilo; ; Acetic ester; Acetoxyethane; Aethylacetat; Essigester; Ethyl ethanoate; hylacetaat; Ethyle (acetate d'); hylester kyseliny octove; Etile (Acetato Di); tan etylu CAS NO:141-78-6
ETHYL METHYL KETOXIME
Ethyl methyl ketoxime functions by binding the drying agents, metal salts that catalyze the oxidative crosslinking of drying oils.
Ethyl methyl ketoxime is the organic compound with the formula C2H5C(NOH)CH3.
Ethyl methyl ketoxime, as it is called in the paint industry, is used to suppress "skinning" of paints: the formation of a skin on paint before it is used.

CAS Number: 96-29-7
Molecular Formula: C4H9NO
Molecular Weight: 87.12
EINECS Number: 406-930-7

2-BUTANONE OXIME, Methyl ethyl ketoxime, 2-Butanone, oxime, 96-29-7, Ethyl methyl ketoxime, (2E)-butan-2-one oxime, (NE)-N-butan-2-ylidenehydroxylamine, DTXCID701821, 2-Butoxime, Pentan-2-one,oxime, Butan-2-one, oxime, Skino No. 2, 2-Butanone oxime,C4H9NO,96-29-7, CAS-96-29-7, Aron M 1, SKINO 2, butan-2-one (Z)-oxime, DTXSID1021821, 2-Butanone oxime, 99%, 2-butanone, oxime, (2E)-, CHEMBL2139230, Tox21_201706, Tox21_300162, MFCD00013935, AKOS008939678, AM90385, NCGC00091699-01, NCGC00091699-02, NCGC00091699-03, NCGC00254161-01, NCGC00259255-01

Ethyl methyl ketoxime is commonly used as a chemical intermediate in various industrial processes.
Its primary function is as a blocking agent or scavenger for reactive carbonyl compounds, such as aldehydes and ketones.
Ethyl methyl ketoxime is derived from the ketone methyl ethyl ketone (MEK) and belongs to the oxime class of compounds.

This colourless liquid is the oxime derivative of Ethyl methyl ketoxime.
Ethyl methyl ketoxime is particularly used in alkyd paints.
Once the paint is applied to a surface, Ethyl methyl ketoxime evaporates, thereby allowing the drying process to proceed.

Other antiskinning agents have been used, including phenolic antioxidants (E.G butylated hydroxytoluene), but these tend to yellow the paint.
This oxime is also used in some types of RTV silicones.
Ethyl methyl ketoxime, is a chemical compound with the molecular formula C4H9NO

The chemical structure of Ethyl methyl ketoxime consists of a ketone group (C=O) replaced by an oxime group (-C=N-OH) at the alpha carbon position of the ketone molecule.
Ethyl methyl ketoxime is a colorless or light yellow oily transparent liquid that has strong complexation with metal ions and is volatile in the air.
Ethyl methyl ketoxime can react with hydrochloric acid and sulfuric acid to form methyl ethyl ketone.

Ethyl methyl ketoxime is the organic compound with the formula C2H5C(NOH)CH3.
This colorless liquid is the oxime derivative of methyl ethyl ketone.
Ethyl methyl ketoxime, as it is called in the paint industry, is used to suppress the "skinning" of paints: the formation of a skin on the paint before it is used.

Ethyl methyl ketoxime is a solvent that is often used in the production of methyl ethyl ketone oxime (MEKO), as well as in other industrial applications.
The process of producing Ethyl methyl ketoxime involves the reaction of MEK with hydrogen peroxide and ammonia.
The resulting product is then purified to obtain MEKO.

Ethyl methyl ketoxime is used as an anti-skinning agent in paints, coatings, and printing inks.
Ethyl methyl ketoxime reacts with oxygen-sensitive drying agents, such as cobalt and manganese salts, to prevent the formation of surface skins or gels during storage and handling.
In adhesive formulations, Ethyl methyl ketoxime acts as an inhibitor to prevent the premature curing or crosslinking of reactive components, such as isocyanates in polyurethane adhesives.

Ethyl methyl ketoxime helps extend the working time and pot life of adhesives and sealants.
Ethyl methyl ketoxime is utilized as a polymerization inhibitor in various polymerization processes, including acrylics, vinyl acetate, and styrene monomers.
Ethyl methyl ketoxime scavenges free radicals and inhibits chain propagation reactions, thereby controlling the polymerization rate and preventing gelation or premature curing.

Ethyl methyl ketoxime is added to metalworking fluids, such as cutting oils and coolants, as a corrosion inhibitor and stabilizer.
Ethyl methyl ketoxime helps protect metal surfaces from corrosion by forming a protective film and scavenging corrosive species, such as aldehydes and peroxides, generated during machining operations.
In the photographic industry, Ethyl methyl ketoxime is used as a stabilizer and inhibitor in developing solutions and fixers.

Ethyl methyl ketoxime helps prevent the oxidation and degradation of photographic emulsions and chemicals, prolonging their shelf life and maintaining image quality.
Ethyl methyl ketoxime is composed of methyl ethyl ketone, hydroxylammonium phosphate, and other auxiliaries.
Among them, Ethyl methyl ketoxime accounts for 72%, hydroxylammonium phosphate accounts for 24%, and auxiliaries account for 4%.

Ethyl methyl ketoxime is typically applied to MEKO in a manufacturing setting, where it may be used as a solvent or reactant in various industrial processes.
Ethyl methyl ketoxime is often used as an anti-skinning agent in paints and coatings, where it helps to prevent the formation of a film on the surface of the paint when it is exposed to air.
Ethyl methyl ketoxime is also used as a cross-linking agent in some types of coatings, where it helps to improve the adhesion and durability of the coating.

Ethyl methyl ketoxime is obtained by the reaction of butanone and hydroxylamine hydrochloride.
Ethyl methyl ketoxime can also be synthesized by the reaction between butanone and hydroxylamine sulfate.
Ethyl methyl ketoxime is the organic compound with the formula C2H5C(NOH)CH3.

This colourless liquid is the oxime derivative of Ethyl methyl ketoxime.
Ethyl methyl ketoxime, as it is called in the paint industry, is used to suppress the "skinning" of paints: the formation of a skin on the paint before it is used.
Ethyl methyl ketoxime functions by binding the drying agents, metal salts that catalyze the oxidative crosslinking of drying oils.

Once the paint is applied to a surface, Ethyl methyl ketoxime, thereby allowing the drying process to proceed.
Other anti skinning agents have been used, including phenol-based antioxidants, but these tend to yellow the paint.
Ethyl methyl ketoxime is also used in some types of RTV silicones.

Ethyl methyl ketoxime, commonly referred to as MEKO, is a chemical compound with the molecular formula C5H11NO.
Ethyl methyl ketoxime is categorised as an oxime Crosslinker for silicones and is characterised by its distinctive odour.
Ethyl methyl ketoxime is a colourless to pale yellow liquid that is soluble in water and commonly used for its reactivity with compounds containing isocyanate groups.

Ethyl methyl ketoxime has several valuable applications across different industries.
Ethyl methyl ketoxime, also known as 2-butanone oxime or MEK-oxime, is an industrial antioxidant used as an antiskinning agent in paints.
Ethyl methyl ketoxime is also used as a blocking agent for urethane polymers, as a corrosion inhibitor in industrial boilers, and can be found in some adhesives, caulking products and repair products that may be used by consumers.

Because of the wide range of industrial and consumer uses for this chemical, one might expect exposures to both workers and consumers.
Ethyl methyl ketoxime passed the animal data screen, underwent a preliminary toxicological evaluation, and is being brought to the Carcinogen Identification Committee for consultation.
This is a compilation of the relevant studies identified during the preliminary toxicological evaluation.

Ethyl methyl ketoxime is primarily used as an anti-skinning agent for oil and latex paints and coatings.
Ethyl methyl ketoxime is also widely used as an isocyanate-blocking agent in electrodeposition coating priming, paint jobs and as a curing agent for silicon rubber due to its outstanding water and heat resistance.
Ethyl methyl ketoxime or butanone oxime, is a substance used to prevent the skinning of some solvent-borne paints in the container or prior to use.

Once the paint is applied to a surface, the Ethyl methyl ketoxime evaporates, thereby allowing the drying process to proceed.
Historically, Ethyl methyl ketoxime has been used by the industry for many years as it is a very effective anti-skinning agent.
Ethyl methyl ketoxime is an essential chemical used as an anti-skinning agent in paints and lacquers, as a blocking-agent for isocyanate in polyurethanes, and in the manufacture of oxime silanes (that are used as crosslinkers for silicone sealants).

Ethyl methyl ketoxime is a high production volume (HPV) chemical produced at over one million pounds annually.
AdvanSix has established a provisional occupational exposure limit of 3 ppm (10 mg/m3) for an 8-hour timeweighted average and a short-term exposure limit of 10 ppm for use in worksite safety programs.
Ethyl methyl ketoximeis a clear, colorless, combustible liquid.

Ethyl methyl ketoxime is severely irritating to eyes.
If Ethyl methyl ketoxime gets into the eyes, immediately flush with plenty of water and seek medical attention to avoid serious damage.
Ethyl methyl ketoxime is moderately toxic in the unlikely event of ingestion.

Ingesting or breathing high concentrations may cause harmful, but reversible, effects on the blood (anemia) and inhalation can irritate nasal passages.
Ethyl methyl ketoxime is slightly irritating to skin and can be absorbed through the skin to cause harmful effects on the blood and nervous system.
Ethyl methyl ketoxime on the skin may cause an allergic response in certain individuals.

Ethyl methyl ketoxime is rapidly metabolized and eliminated from the body.
Ethyl methyl ketoxime does not cause harmful effects on reproduction or development.
Male rodents developed liver tumors when repeatedly exposed during their lifetime to high concentrations of Ethyl methyl ketoxime.

These tumors developed late in life and did not affect survival.
Ethyl methyl ketoxime is not genotoxic, pointing to a threshold mechanism for cancer development (i.e., a “safe level” below which cancer will not occur: a level well above typical exposures). Therefore, the human risk of cancer is low.
Ethyl methyl ketoxime has low toxicity to aquatic organisms, upon either single or repeated exposure.

Ethyl methyl ketoxime has minimal potential to accumulate in the bodies of humans or animals.
Ethyl methyl ketoxime is readily biodegradable and will not persist in the environment.
Ethyl methyl ketoxime by AdvanSix is a high-efficiency anti-skinning agent for use in air-drying paints, inks and coatings.

Ethyl methyl ketoxime meets low moisture and high assay standards.
Ethyl methyl ketoxime helps in improving the functionality of polyurethane coatings for coil-, automotive- and other industrial coatings.
Ethyl methyl ketoxime is an essential chemical used as an anti-skinning agent in paints and lacquers, as a blocking-agent for isocyanate in polyurethanes, and in the manufacture of oxime silanes (that are used as crosslinkers for silicone sealants).

Ethyl methyl ketoxime is a High Production Volume (HPV) chemical produced at over 1,000,000 pounds annually.
Honeywell, as a member of a consortium, has sponsored Ethyl methyl ketoxime under EPA’s HPV Challenge program and the Organisation for Economic Co-operation and Development’s HPV Programme.
Honeywell has established a provisional occupational exposure limit of 3 ppm (10 mg/m3) for an 8-hour time-weighted average and a short-term exposure limit of 10 ppm for use in worksite safety programs.

Ethyl methyl ketoxime is a clear, colorless combustible liquid.
Ethyl methyl ketoxime is severely irritating to eyes.
If it gets into the eyes, immediately flush with plenty of water and seek medical attention to avoid serious damage.

Ethyl methyl ketoxime is moderately toxic in the unlikely event of ingestion.
Ingesting or breathing high concentrations may cause harmful, but reversible, effects on the blood (anemia) and inhalation can irritate nasal passages.
Ethyl methyl ketoxime is slightly irritating to skin, and can be absorbed through the skin to cause harmful effects on the blood and nervous system.

Getting Ethyl methyl ketoxime on the skin may cause an allergic response in certain individuals.
Ethyl methyl ketoxime is rapidly metabolized and eliminated from the body.
Ethyl methyl ketoxime does not cause harmful effects on reproduction or development.

Ethyl methyl ketoxime is sensitive to heat. Has exploded at least twice when heated in the presence of acidic impurities.
Reacts with oxidizing agents.
Mixtures with strong acids may explode.

Reacts with sulfuric acid to form an explosive product .
Ethyl methyl ketoxime is an organic substance that is added to a paint to inhibit the reaction of the drier with (atmospheric) oxygen by binding the oxygen or by complexing of the drier metal.
Ethyl methyl ketoxime is the organic compound with the formula C2H5C(NOH)CH3.

Ethyl methyl ketoxime is a highefficiency anti-skinning agent used for air-drying paints, inks and coatings.
Ethyl methyl ketoxime is also used to improve the shelf life of silicone adhesives and sealants, and the functionality of polyurethane coatings.
Ethyl methyl ketoxime is also widely used as an isocyanate-blocking agent in priming automobiles (electrodeposition coating) for paint jobs and as a curing agent for silicon rubber due to its outstanding water and heat resistance.

Ethyl methyl ketoxime is a Urethane blocking agent for coating applications.
Ethyl methyl ketoxime can be used as an Anti-skinning agent in paints (Alkyd based systems).
Ethyl methyl ketoxime is an Oxygen scavenger in boiler water treatment.

Ethyl methyl ketoxime can be used to produce oxime derivatives for other industrial applications.
Without the use of suitable additives, alkyd based paints will form skins in the paint tin which need to be carefully removed prior to use.
Traditionally the paint industry has used a slow evaporating solvent called Ethyl methyl ketoxime to prevent skins from forming in the paint can.

The Ethyl methyl ketoxime additive is added in very small proportions to the paint typically less than 0.5%.
Ethyl methyl ketoxime is primarily used as an anti-skinning agent for oil and latex paints and coatings.

Ethyl methyl ketoxime is also widely used as an isocyanate-blocking agent in priming automobiles for paint jobs and as a curing agent for silicon rubber due to its outstanding water and heat resistance.
Ethyl methyl ketoxime is the organic compound with the formula C2H5C(NOH)CH3.
Ethyl methyl ketoxime is the oxime derivative of methyl ethyl ketone.

Melting point: -30 °C
Boiling point: 59-60 °C15 mm Hg(lit.)
Density: 0.924 g/mL at 25 °C(lit.)
vapor density: 3 (vs air)
vapor pressure: refractive index: n20/D 1.442(lit.)
Flash point: 140 °F
solubility: water: soluble100g/L at 25°C
form: Liquid
pka: pK1:12.45 (25°C)
color: Clear colorless to pale yellow
Water Solubility: 114 g/L (20 ºC)
BRN: 1698241
Dielectric constant: 3.4(20℃)
Stability: Stable. Combustible. Incompatible with strong oxidizing agents. May react with strong acids to form an explosive material.
InChIKey: WHIVNJATOVLWBW-SNAWJCMRSA-N
LogP: 0.63 at 25℃

Ethyl methyl ketoxime is well known as an oxygen scavenger and metal passivator in boilers.
For more than a decade, Ethyl methyl ketoxime has proven effective in suppressing dissolved oxygen throughout the utility steam cycle.
The protective film formed appears to be less susceptible to flow assisted corrosion than the magnetite film formed with most of the other scavengers.

This results in reduced metal oxide transport into the boiler and reduced metal oxide deposition in the boiler.
At elevated dosages, Ethyl methyl ketoxime contributes to removal of oxides from the boiler.
This can extend the time between chemical cleaning, reducing overall costs and extending boiler life expectancy.

Ethyl methyl ketoxime knows as a novel oxygen scavenger is disclosed in the U.S. and patented by Drew Chemical Company in 1984.
Ethyl methyl ketoxime displays low toxicity, efficiency, fast-performance, and a blunt protective effects.
In Europe and other developed countries it has been widely applied, and China it is also successfully developed in the nineties, and has been successful in promotion.

Oxygen scavenging performance: oxime compound is an organic compound with an oxime group.
Ethyl methyl ketoximes are currently used for boiler shutdown protection and oxygen mainly acetaldehyde oxime, dimethyl ketone oxime (acetone oxime) and methyl ethyl ketone oxime.
Ethyl methyl ketoximes have a strong reduction, easy to react with oxygen.

When put in a wide temperature and pressure ranges, oximes has good oxygen scavenging performance.
The optimum temperature range is 138~336 ℃, and pressure range is 0.3~13.7Mpa.
According to comparative experiments, under the same conditions, the rate of oxygen and oxygen efficiency oximes is higher than that of hydrazine.

Corrosion and passivation: oximes can restore high iron and copper oxide into suboxide, which can be a good solution in the steel magnetic oxide film formed on the surface of the metal surface passivation plays well, corrosion inhibition.
Where in Ethyl methyl ketoxime is the best, using the minimum amount required.
According to comparative experiments, oxime compounds having the same passivation, corrosion inhibition hydrazine, can significantly reduce the iron content in solution at high temperature and pressure conditions.

The steel has a protective effect, among which the Ethyl methyl ketoxime is best, which requires the least amount.
Meanwhile, Ethyl methyl ketoximes have cleaning actions to copper corrosion products deposited in the pipeline, economizer, etc., which is in the initial period of oximes.
This is the reason why furnace copper water content is significantly higher.

Volatile: the volatile degree of Ethyl methyl ketoximes is higher than that of hydrazine, DEHA, morpholine, cyclohexylamine, etc.
Ethyl methyl ketoxime is close to the volatility of NH3.
When the steam condenses, highly volatile oxygen scavenger will has a certain amount of condensation agent which is dissolved in water, therefore, helpful to protect the condensate system metal material.

By experiments under the high temperature and pressure conditions, the decomposition products of oxime compound is NH3, N2, H2O, trace of acetic acid, formic acid produces, no adverse effects on water vapor system.
Low toxicity: based on the data comparison of LD50, the LD50 for hydrazine is 290mg/kg, acetaldehyde oxime is 1900mg/kg, methyl ethyl ketone oxime is 2800mg/kg, dimethylket oximino 5500mg/kg.
So the toxicity of hydrazine is very strong, and toxicity of oxime compound is very small.

Ethyl methyl ketoxime belongs to low toxicity compounds.
Test through the skin and mucous membrane contact with oxygen scavengers showed no significant oximes oxygen scavenger irritation and damage, but hydrazine causes damage of skin irritation, erosion, mucosal hyperemia.
Ethyl methyl ketoxime is the organic compound with the formula C2H5C(NOH)CH3.

This colourless liquid is the oxime derivative of methyl ethyl ketone.
Ethyl methyl ketoxime, as it is called in the paint industry, is used to suppress the "skinning" of paints: the formation of a skin on the paint before it is used.
Ethyl methyl ketoxime functions by binding the drying agents, metal salts that catalyze the oxidative crosslinking of drying oils.

Once the paint is applied to a surface, Ethyl methyl ketoxime evaporates, thereby allowing the drying process to proceed.
Anti skinning agents have been used, including phenol-based antioxidants, but these tend to yellow the paint.
Ethyl methyl ketoxime is also used in some types of RTV silicones.

Colourless and pigmented oxidatively drying paints and coatings based on oxidatively drying oils, alkyd resins, epoxy esters and other oxidatively drying refined oils are known.
These oils and binders crosslink oxidatively under the influence of oxygen (preferably atmospheric oxygen) by means of the addition of driers, such as metal carboxylates of transition metals; If this crosslinking takes place before the product is actually used, a solid barrier film, a skin, can form on the surface.
Skin formation can occur in open or closed containers.

This is highly undesirable and should therefore be avoided since it makes the paint more difficult to work with, and commonly interferes with the uniform distribution of the driers.
The accumulation of the driers in the paint skin that forms can lead to considerable delays in the drying of the paint when it is applied.
Skinning of the paint film after the application is also disadvantageous.

Excessively rapid drying of the surface of the paint prevents the lower film layers from drying evenly because they are shielded from oxygen, which is prevented from sufficiently penetrating into and dispersing within the paint film.
This can lead among other things to flow problems in the paint film, adhesion problems, or insufficiently hard films.
Ethyl methyl ketoxime is known to add organic substances to a paint that inhibit the reaction of the drier with (atmospheric) oxygen by binding the oxygen or by complexing the drier metal.

Ethyl methyl ketoxime is a high-efficiency anti-skinning agent used for air-drying paints, inks and coatings.
Ethyl methyl ketoxime is also used to improve the shelf life of silicone adhesives and sealants, and the functionality of polyurethane coatings.
Ethyl methyl ketoxime is produced to meet the low moisture and high assay standards that formulators require.

Ethyl methyl ketoxime is used as an anti-skinning agent for various oil-based paints, alcohol acid paints and epoxy resin paints during storage and delivery.
Ethyl methyl ketoxime can also be used as a silicone curing agent.
Its main uses are anti-skinning and silicone curing for alcohol acid and resin coatings.

As an anti-skin and anti-oxidation agent, the product provides a better effect than Butyraldehyde oxime and cyclohexanone oxime.
Ethyl methyl ketoxime can also be used for the synthesis of aqueous polyurethane resin
Ethyl methyl ketoxime, have another name called Diacetylmonoxime (Methyl ethyl ketoxime or 2-butanon oxime, MEKO), it can be used as the linking agent raw material of silicon, also can be used as paint anti and boiler feedwater oxygen scavenger is a fine chemical product that industrial value is arranged very much.

At present, industrial production mainly adopts hydroxylamine assay both at home and abroad, i.e. methylethylketone and oxammonium hydrochloride or oxammonium sulfate reaction
With suitable precautions, to 1 liter of the sodium hydroxylamine di­sulfonate solution from Preparation 2-1 (approx. 1.2 moles) is added 72 gm (1 mole) of methyl ethyl ketone.
Then the reaction flask is wrapped with insulation and allowed to cool slowly for 12 hr.

After neutralization with 48% sodium hydroxide solution, the oxime is extracted from the reaction mixture with benzene.
The benzene solution is distilled fractionally. The product distills between 152° and 154°C; yield, 65 gm (75%).
Ethyl methyl ketoxime is the organic compound with the formula C2H5C(NOH)CH3.

This colourless liquid is the oxime derivative of methyl ethyl ketone.
Ethyl methyl ketoxime, as it is called in the paint industry, is used to suppress "skinning" of paints: the formation of a skin on paint before it is used.
Ethyl methyl ketoxime functions by binding the drying agents, metal salts that catalyze the oxidative crosslinking of drying oils.

Once the paint is applied to a surface, Ethyl methyl ketoxime evaporates, thereby allowing the drying process to proceed.
Antiskinning agents have including phenol-based antioxidants, but these tend to yellow the paint.
Ethyl methyl ketoxime is also used in some types of RTV silicones.

Ethyl methyl ketoxime synonymous with 2-Butanone Oxime, is a clear, colorless liquid that is 99.5% pure.
Ethyl methyl ketoxime is primarily used as an anti-skinning agent in paint.
Ethyl methyl ketoxime has additional uses in the production of silicone adhesive products.

Uses:
Ethyl methyl ketoxime is mainly used as anti-skinning agent and silicon curing agent for alkyd resin coatings.
Ethyl methyl ketoxime is used as an antioxidant to prevent skin formation, which is better than butyraldehyde oxime and cyclohexanone oxime.
For a variety of oil-based paint, alkyd paint, epoxy paint, such as esters during storage and transportation of anti-skinning process, also used as a curing agent silicon.

Ethyl methyl ketoxime was employed as reagent and solvent in the syntheses of ketoimine and 2,4-dipyridyl-1,3,5-triazapentadiene palladium(II) complexes.
Ethyl methyl ketoxime was also used in the synthesis of novel acetaldiimine cobalt complex, [CoI2{((CH3CH2)(CH3)C=NO)2C(CH3)2}].
Ethyl methyl ketoxime is used primarily as an antiskinning agent in alkyd coating resins

Ethyl methyl ketoxime is used in the following products: coating products.
Ethyl methyl ketoxime is used in the following areas: building & construction work.
Ethyl methyl ketoxime is used for the manufacture of: wood and wood products, pulp, paper and paper products, plastic products, fabricated metal products, electrical, electronic and optical equipment, machinery and vehicles and furniture.

Other release to the environment of Ethyl methyl ketoxime is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
Ethyl methyl ketoxime is used in the following products: coating products and polymers.
Release to the environment of Ethyl methyl ketoxime can occur from industrial use: formulation of mixtures.

Ethyl methyl ketoxime is used in the following products: coating products.
Ethyl methyl ketoxime has an industrial use resulting in manufacture of another substance (use of intermediates).
Ethyl methyl ketoxime is used in the following areas: formulation of mixtures and/or re-packaging.

Ethyl methyl ketoxime is used for the manufacture of: chemicals.
Release to the environment of Ethyl methyl ketoxime can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, manufacturing of the substance and formulation of mixtures.
Ethyl methyl ketoxime is primarily used as an anti-skinning agent for oil and latex paints and coatings.

Ethyl methyl ketoxime is also widely used as an isocyanate-blocking agent in priming automobiles (electrodeposition coating) for paint jobs and as a curing agent for silicon rubber due to its outstanding water and heat resistance.
Ethyl methyl ketoxime is a kind of oil-based coating antioxidant, used for anti-skinning treatment during the storage and transportation of a paint, alkyd paint, epoxy ester paint and etc. Mainly used as an anti-skinning agent and viscidity stabilizer for alkyd resin coating.

As an anti-skinning agent, Ethyl methyl ketoxime is recommended to be added in the amount of 0.1-0.3% after a test to determine the best usa.
Ethyl methyl ketoxime of high purity can be used in the synthesis of silicone cross-linking agent, silicon curing agent and isocyanate sealant.
Ethyl methyl ketoxime can be used in offset printing ink and other industries, and used as corrosion inhibitor in industrial boiler or water trea.

Ethyl methyl ketoxime can also be used as wood preservative and pharmaceutical intermediate for alum and magnesium removal and etc.
Ethyl methyl ketoxime can be used to produce high purity hydroxylamine sulfate, hydroxylamine hydrochloride and etc.
Ethyl methyl ketoxime is widely used as a protective, anti-skinning agent for paints and coatings.

Ethyl methyl ketoxime is also suitable for use as a raw material to make hardeners for silicon rubber compounds and electrodeposition coatings.
Ethyl methyl ketoxime is used in the following products: coating products.
Ethyl methyl ketoxime has an industrial use resulting in the manufacture of another substance (use of intermediates).

Ethyl methyl ketoxime is used in the following areas: formulation of mixtures and/or re-packaging.
Ethyl methyl ketoxime is used for the manufacture of chemicals.
Release to the environment of Ethyl methyl ketoxime can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), manufacturing of the substance, formulation of mixtures and as a processing aid.

The use of Ethyl methyl ketoxime does not adversely affect the cycle chemistry or the performance of ion exchange type condensate polishers.
Ethyl methyl ketoxime is primarily used as an anti-skinning agent for oil and latex paints and coatings.
Ethyl methyl ketoxime is also widely used as an isocyanate-blocking agent in priming automobiles (electrodeposition coating) for paint jobs and as a curing agent for silicon rubber due to its outstanding water and heat resistance.

Ethyl methyl ketoxime is a kind of oil-based coating antioxidant, used for anti-skinning treatment during the storage and transportation of a variety of oil-based paint, alkyd paint, epoxy ester paint and etc.
Mainly used as an anti-skinning agent and viscidity stabilizer for alkyd resin coating.
As an anti-skinning agent, Ethyl methyl ketoxime is recommended to be added in the amount of 0.1-0.3% after a test to determine the best usage and dosage.

Ethyl methyl ketoxime of high purity can be used in the synthesis of silicone cross-linking agent, silicon curing agent and isocyanate sealant.
Ethyl methyl ketoxime can be used in offset printing ink and other industries and used as a corrosion inhibitor in industrial boiler or water treatment system.
Ethyl methyl ketoxime can also be used as a wood preservative and pharmaceutical intermediate for alum and magnesium removal and etc.

Ethyl methyl ketoxime can be used to produce high purity hydroxylamine sulfate, hydroxylamine hydrochloride and etc.
Without the use of suitable additives, alkyd based paints will form skins in the paint tin which need to be carefully removed prior to use.
Traditionally the paint industry has used a slow evaporating solvent called Methyl Ethyl Ketoxime to prevent skins from forming in the paint can.

Ethyl methyl ketoxime is a high-efficiency anti-skinning agent used for air-drying paints, inks and coatings.
Ethyl methyl ketoxime is also used to improve the shelf life of silicone adhesives and sealants, and the functionality of polyurethane coatings.
Ethyl methyl ketoxime is produced to meet the low moisture and high assay standards that formulators require.

Ethyl methyl ketoxime is an essential chemical used as an anti-skinning agent in paints and lacquers, as a blocking agent for isocyanate in polyurethanes, and in the manufacture of oxime silanes (that are used as crosslinkers for silicone sealants).
Ethyl methyl ketoxime is a High Production Volume (HPV) chemical produced at over 1,000,000 pounds annually.
Ethyl methyl ketoxime is a clear, colourless combustible liquid.

Ethyl methyl ketoxime is severely irritating to the eyes.
If it gets into the eyes, immediately flush with plenty of water and seek medical attention to avoid serious damage.
Ethyl methyl ketoxime is moderately toxic in the unlikely event of ingestion.

Ethyl methyl ketoxime is often used as an anti-skinning agent in coatings and paints.
Ethyl methyl ketoxime prevents the formation of a skin or surface film when the product is exposed to air, thus extending the shelf life of these materials.
In the production of adhesives and sealants, Ethyl methyl ketoxime acts as a crosslinking agent.

Ethyl methyl ketoxime helps improve the durability and performance of these products.
Ethyl methyl ketoxime is employed as an inhibitor in industrial processes involving isocyanate compounds, such as the production of polyurethane foams.

Ethyl methyl ketoxime stabilizes these compounds, preventing premature reactions.
Some silicone sealants use MEKO as a curing agent, aiding in the hardening and setting of the sealant.

Safety Profile:
Poison by intraperitoneal route.
Moderately toxic by subcutaneous route.
May explode if heated.

Reacts with sulfuric acid to form an explosive product.
When heated to decomposition Ethyl methyl ketoxime emits toxic fumes of NOX.

ETHYL NICOTINATE
Ethyl Nicotinate is an ester of ethyl alcohol and nicotinic acid.
Ethyl Nicotinate is an active substance from the group of rubefacients that stimulates blood circulation.


CAS Number: 614-18-6
Molecular Formula: C8H9NO2


Ethyl Nicotinate is a heterocyclic building block.
Ethyl Nicotinate, also known as nicotine acid ethyl ester or mucotherm, is a member of the class of compounds known as pyridinecarboxylic acids.
Pyridinecarboxylic acids are compounds containing a pyridine ring bearing a carboxylic acid group.


Ethyl Nicotinateis soluble (in water) and a strong basic compound (based on its pKa).
Ethyl Nicotinate can be found in sweet orange, which makes ethyl nicotinate a potential biomarker for the consumption of this food product.
Ethyl Nicotinate exists in all eukaryotes, ranging from yeast to humans.


Ethyl Nicotinate belongs to the class of organic compounds known as pyridinecarboxylic acids.
Pyridinecarboxylic acids are compounds containing a pyridine ring bearing a carboxylic acid group.
Ethyl Nicotinate is miscible with water.


Ethyl Nicotinate is air and light sensitive.
Keep Ethyl Nicotinate the container tightly closed in a dry and well-ventilated place.
Ethyl Nicotinate is incompatible with strong oxidizing agents.


Ethyl Nicotinate, also known as mucotherm, belongs to the class of organic compounds known as pyridinecarboxylic acids.
Pyridinecarboxylic acids are compounds containing a pyridine ring bearing a carboxylic acid group.
Ethyl Nicotinate is a strong basic compound (based on its pKa).


Outside of the human body, Ethyl Nicotinate has been detected, but not quantified in, sweet oranges.
This could make Ethyl Nicotinate a potential biomarker for the consumption of these foods.
These are compounds containing a pyridine ring bearing a carboxylic acid group.


Ethyl Nicotinate is a clear colourless to yellow liquid
Ethyl Nicotinate is a member of pyridines and an aromatic carboxylic acid.
Ethyl Nicotinate is a nicotinic acid derivative that has a high affinity for magnesium.



USES and APPLICATIONS of ETHYL NICOTINATE:
Ethyl Nicotinate is used for topical treatment of muscle, joint and ligament pain.
Ethyl Nicotinate can be used in creams, baths and emulsions, in veterinary as well as in human medicines.
Ethyl Nicotinate is used for skin-conditioning cosmetics.


Ethyl Nicotinate is principally used in medicine as a local vasodilator at a concentration of 1 to 2 % in creams, ointments and pomades.
Ethyl Nicotinate is utilized for the treatment sprains, wrenches, muscular pains and tendonitis.
Ethyl Nicotinate is a nicotinic acid derivative used for skin-conditioning cosmetics.


Ethyl Nicotinate is used for skin-conditioning cosmetics.
Ethyl Nicotinate is principally used in medicine as a local vasodilator at a concentration of 1 to 2 % in creams, ointments and pomades.
Ethyl Nicotinate is utilized for the treatment sprains, wrenches, muscular pains and tendonitis.


Ethyl Nicotinate is used for skin-conditioning cosmetics.
Ethyl Nicotinate is principally used in medicine as a local vasodilator at a concentration of 1 to 2 % in creams, ointments and pomades.
Ethyl Nicotinate is utilized for the treatment sprains, wrenches, muscular pains and tendonitis.


Ethyl Nicotinate is used as an ingredient in skin care products to improve the appearance of aging skin.
Ethyl Nicotinate binds to the magnesium ion, which acts as an electron donor, and forms an electrochemical complex.
This complex can catalyze the oxidation of hydrochloric acid to form picolinic acid and hydrogen chloride gas, which are thought to be responsible for its exfoliating properties.


The coordination geometry of Ethyl Nicotinate depends on the counterion it binds with, with either octahedral or square pyramidal geometries possible.
The nitrogen atoms are primarily bound to carbon atoms in Ethyl Nicotinate, with two lone pairs of electrons pointing away from the molecule in opposite directions.
Ethyl Nicotinate is an active substance from the group of rubefacients that stimulates blood circulation.


Ethyl Nicotinate is used for topical treatment of muscle, joint and ligament pain.
Ethyl Nicotinate can be used in creams, baths and emulsions, in veterinary as well as in human medicines.
Comprehensive documentation for drug registration of Ethyl Nicotinate can be provided by Biesterfeld as referred.



ALTERNATIVE PARENTS OF ETHYL NICOTINATE:
*Heteroaromatic compounds
*Carboxylic acid esters
*Monocarboxylic acids and derivatives
*Azacyclic compounds
*Organopnictogen compounds
*Organooxygen compounds
*Organonitrogen compounds
*Organic oxides
*Hydrocarbon derivatives



SUBSTITUENTS OF ETHYL NICOTINATE:
*Pyridine carboxylic acid
*Heteroaromatic compound
*Carboxylic acid ester
*Azacycle
*Monocarboxylic acid or derivatives
*Carboxylic acid derivative
*Organic nitrogen compound
*Organic oxygen compound
*Organopnictogen compound
*Organic oxide
*Hydrocarbon derivative
*Organooxygen compound
*Organonitrogen compound
*Aromatic heteromonocyclic compound



PHYSICAL and CHEMICAL PROPERTIES of ETHYL NICOTINATE:
Physical State : Liquid
Solubility : Soluble in water (50 mg/ml at 20° C).
Storage : Store at 4° C
Melting Point :8-10° C (lit.)
Boiling Point :223-224° C (lit.)
Density :1.11 g/mL at 20° C
Refractive Index :n20D 1.50
pK Values :
pKa: 3.35 at 20° C
Water Solubility: 114 g/L
logP: 1.17
logP: 1.12
logS: -0.12
pKa (Strongest Basic): 3.24
Physiological Charge: 0
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 0

Polar Surface Area: 39.19 Ų
Rotatable Bond Count: 3
Refractivity: 40.68 m³·mol⁻¹
Polarizability: 15.3 ų
Number of Rings: 1
Bioavailability: Yes
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: Yes
MDDR-like Rule: No
Chemical Formula: C8H9NO2
IUPAC name: ethyl pyridine-3-carboxylate
InChI Identifier: InChI=1S/C8H9NO2/c1-2-11-8(10)7-4-3-5-9-6-7/h3-6H,2H2,1H3
InChI Key: XBLVHTDFJBKJLG-UHFFFAOYSA-N
Isomeric SMILES: CCOC(=O)C1=CN=CC=C1
Average Molecular Weight: 151.1626
Monoisotopic Molecular Weight: 151.063328537

Boiling Point: Bp 223-224°
Charge: Not Available
Density: Not Available
Experimental logP: 1.32 HANSCH,C ET AL. (1995)
Experimental pKa: 3.35
Experimental Water Solubility: 56 mg/mL at 25 oC
Isoelectric point: Not Available
Mass Composition: C 63.57%; H 6.00%; N 9.27%; O 21.17% DFC
Melting Point: Mp 126-127° (as hydrochloride) DFC
Optical Rotation: Not Available
CAS: 614-18-6
Molecular Formula: C8H9NO2
Molecular Weight (g/mol): 151.165
MDL Number: MFCD00006389
InChI Key: XBLVHTDFJBKJLG-UHFFFAOYSA-N

Melting Point: 8°C to 9°C
Density: 1.107
Boiling Point: 223°C to 224°C
Flash Point: 93°C (199°F)
Odor: Characteristic
Refractive Inde: 1.503
Beilstein: 122937
Solubility Information: Miscible with water.
Formula Weight: 151.17
Percent Purity: 99%
Chemical Name or Material: Ethyl nicotinate

CBNumber:CB0382500
Molecular Formula:C8H9NO2
Molecular Weight:151.16
MDL Number:MFCD00006389
MOL File:614-18-6.mol
Melting point: 8-10 °C (lit.)
Boiling point: 223-224 °C (lit.)
Density: 1.107 g/mL at 25 °C (lit.)
vapor pressure: 4.2-5.5Pa at 20-25℃
refractive index: n20/D 1.504(lit.)
Flash point: 93 °C

storage temp.: Store below +30°C.
solubility: 50g/l
form: neat
pka: pK1:3.35(+1) (25°C)
Specific Gravity: 1.107
color: light yellow
Water Solubility: miscible
BRN: 122937
InChIKey: XBLVHTDFJBKJLG-UHFFFAOYSA-N
LogP: 1.32
Surface tension: 72mN/m at 1g/L and 20℃
CAS DataBase Reference: 614-18-6(CAS DataBase Reference)
EWG's Food Scores: 1
FDA UNII: NIJ3H353YH
NIST Chemistry Reference: 3-Pyridinecarboxylic acid, ethyl ester(614-18-6)
EPA Substance Registry System: Ethyl nicotinate (614-18-6)

Density: 1.1±0.1 g/cm3
Boiling Point: 224.0±0.0 °C at 760 mmHg
Melting Point: 8-10 °C(lit.)
Molecular Formula: C8H9NO2
Molecular Weight: 151.163
Flash Point: 93.3±0.0 °C
Exact Mass: 151.063324
PSA: 39.19000
LogP: 1.41
Vapour Pressure: 0.1±0.4 mmHg at 25°C
Index of Refraction: 1.506
Storage condition: 2-8°C
Water Solubility: miscible
Formula: C₈H₉NO₂
MW: 151,16 g/mol
Boiling Pt: 223 °C (1013 hPa)
Density: 1,115 g/cm³ (20 °C)
Storage Temperature: Ambient

MDL Number: MFCD00006389
CAS Number: 614-18-6
EINECS: 210-370-7
Molecular form: C8H9NO2
Appearance: Clear Colourless to Pale Yellow Oil
Mol. Weight: 151.16
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: NA
BTM: NA
Solubility: 50 g/l (20 °C)
Melting Point: 8 - 9 °C
Molar Mass: 151.16 g/mol
Boiling Point: 103 - 105 °C (7 hPa)
Flash Point: 93 °C
Refractive Index: 1.504 (20 °C, 589 nm)
Density: 1.11 g/cm3 (20 °C)

IUPAC Name: ethyl 2,4,5,6-tetradeuteriopyridine-3-carboxylate
Solubility: Soluble in Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Storage: Store at 2-8°C
IUPAC Name: ethyl pyridine-3-carboxylate
Molecular Weight: 151.16
Molecular Formula: C8H9NO2
Canonical SMILES: CCOC(=O)C1=CN=CC=C1
InChI: InChI=1S/C8H9NO2/c1-2-11-8(10)7-4-3-5-9-6-7/h3-6H,2H2,1H3
InChIKey: XBLVHTDFJBKJLG-UHFFFAOYSA-N
Boiling Point: 223-224 ℃
Melting Point: 8-9.5°C

Flash Point: 93°C
Purity: 99 %
Density: 1.102 g/cm3
Solubility: water, 5594 mg/L @ 25 °C (est)
Appearance: Clear colorless to light brown liquid
Storage: 2-8°C
Assay: 0.99
EINECS: 210-370-7
Log P: 1.25830
MDL: MFCD00006389
Refractive Index: 1.5019-1.504
Stability: Stable under normal temperatures and pressures.



FIRST AID MEASURES of ETHYL NICOTINATE:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ETHYL NICOTINATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of ETHYL NICOTINATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYL NICOTINATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ETHYL NICOTINATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
*Storage class:
Storage class (TRGS 510): 12:
Non Combustible Liquids



STABILITY and REACTIVITY of ETHYL NICOTINATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
Nicotinic acid ethyl ester
3-Pyridinecarboxylic acid, ethyl ester
Nicotinic acid, ethyl ester
β-Pyridinecarboxylic acid ethyl ester
Ba 2673
Ethyl 3-pyridinecarboxylate
Ignicut
Ignocut
Mucotherm
Nicaethan
Nikethan
Nikithan
3-(Ethoxycarbonyl)pyridine
3-Carbethoxypyridine
NSC 8872
3-(Ethoxycarbonyl)pyridine
3-Carbethoxypyridine
3-Carboethoxypyridine
3-Pyridinecarboxylic acid, ethyl ester
beta-Pyridinecarboxylic acid ethyl ester
Ethyl 3-pyridinecarboxylate
Ethyl nicotinate
Ethyl nicotinic acid
Ethyl pyridine-3-carboxylate
Ethyl-nicotinate
Ethylnicotinate
Mucotherm
Nicotine acid ethyl ester
Nicotinic acid ethyl ester
Nicotinic acid, ethyl ester
Picolinic acid ethyl ester
β-Pyridinecarboxylic acid ethyl ester
ethyl nicotinate, ethyl nicotinoate
nicotinic acid ethyl ester
ethyl 3-pyridinecarboxylate
3-pyridinecarboxylic acid, ethyl ester
ethylnicotinate
nicotinic acid, ethyl ester
mucotherm
nicaethan
nikethan
Nicotine acid ethyl ester
Mucotherm
Ethyl nicotinic acid
Ethyl pyridine-3-carboxylate
3-Carboethoxypyridine
Ethylnicotinate
Ethyl-nicotinate
Nicotinic acid, ethyl ester
NICOTINIC ACID ETHYL ESTER
ETHYL 3-PYRIDINECARBOXYLATE
Ethyl nicotinat
ethyl nicotinoate
ETHYL PYRIDINE-3-CARBOXYLATE
ETHYL 3-PYRIDINECARBOXYLATE FOR SYNTHES
Apamid
Ba 2673
Ignicut
Ignocut
3-Pyridinecarboxylic acid ethyl ester
Ethyl 3-pyridinecarboxylate
Pyridine-3-carboxylic acid ethyl ester
3-Picolinic acid ethyl ester
Nicotinic acid ethyl ester
3-Pyridinecarboxylic Acid Ethyl Ester
Nicotinic Acid Ethyl Ester
3-(Ethoxycarbonyl)pyridine
3-Carbethoxypyridine
Ba 2673
Ethyl 3-Pyridinecarboxylat
Ignicut
Ignocut
Mucotherm
NSC 8872
Nicaethan
Nikethan
Nikithan
β-Pyridinecarboxylic Acid Ethyl Ester
3-Pyridinecarboxylic acid, ethyl ester
Nicotinic acid, ethyl ester
«beta»-Pyridinecarboxylic acid ethyl ester
Ba 2673
Ethyl 3-pyridinecarboxylate
Ignicut
Ignocut
Mucotherm
Nicaethan
Nikethan
Nikithan
3-(Ethoxycarbonyl)pyridine
3-Carbethoxypyridine
NSC 8872
Ethylnicotinate
3-(Ethoxycarbonyl)pyridine
3-Carbethoxypyridine
3-Pyridinecarboxylic acid, ethyl ester
Ba 2673
beta-Pyridinecarboxylic acid ethyl ester
Ethyl 3-pyridinecarboxylate
Ethyl-nicotinate
Ignicut
Ignocut
Mucotherm
Nicaethan
Nikethan
Nikithan
Nicotinic acid, ethyl ester (8CI)
614-18-6
210-370-7
3-PYRIDINECARBOXYLIC ACID, ETHYL ESTER
ETHYL 3-PYRIDINE CARBOXYLATE
ETHYL NICOTINATE [INCI]
ETHYL NICOTINATE [MART.]
ETHYL NICOTINATE [WHO-DD]
ETHYLNICOTINATE
NICOTINIC ACID, ETHYL ESTER
NSC-8872
3-Pyridinecarboxylic Acid-d4 Ethyl Ester
Nicotinic Acid-d4 Ethyl Ester
3-(Ethoxycarbonyl)pyridine-d4
3-Carbethoxypyridine-d4
Ba 2673-d4
Ethyl 3-Pyridinecarboxylate-d4
Ignicut-d4
Ignocut-d4
Mucotherm-d4
NSC 8872-d4
Nicaethan-d4
Nikethan-d4
Nikithan-d4
β-Pyridinecarboxylic Acid-d4 Ethyl Ester
3-Pyridinecarboxylic Acid Ethyl Ester
Nicotinic Acid Ethyl Ester
3-(Ethoxycarbonyl)pyridine
3-Carbethoxypyridine
Ba 2673
Ethyl 3-Pyridinecarboxylate
Ignicut
Ignocut
Mucotherm
NSC 8872
Nicaethan
Nikethan
Nikithan
β-Pyridinecarboxylic Acid Ethyl Ester



ETHYL NICOTINATE
ETHYL OLEATE, N° CAS : 111-62-6. Nom INCI : ETHYL OLEATE, N° EINECS/ELINCS : 203-889-5. Compatible Bio (Référentiel COSMOS). Ses fonctions (INCI). Emollient : Adoucit et assouplit la peau.Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques
ETHYL OLEATE
Nom INCI : ETHYL PALMATE Ses fonctions (INCI) Emollient : Adoucit et assouplit la peau
ETHYL OLEATE
Ethyl Oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol.
Ethyl Oleate is a colorless oil although degraded samples can appear yellow.
Ethyl Oleate also called Oleic acid ethyl ester


CAS NUMBER: 111-62-6

EC NUMBER: 285-206-0

MOLECULAR FORMULA: C20H38O2

MOLECULAR WEIGHT: 310.5 g/mol

IUPAC NAME: ethyl (Z)-octadec-9-enoate


Ethyl Oleate is clear yellow liquid
Ethyl Oleate has a floral odour

Ethyl Oleate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of oleic acid with the hydroxy group of ethanol.
Ethyl Oleate has a role as a plant metabolite and an acaricide.

Ethyl Oleate is functionally related to an oleic acid.
Ethyl Oleate is a natural product found in Azadirachta indica, Cinnamomum camphora, and other organisms with data available.

Ethyl Oleate is insoluble in water
Ethyl Oleate is soluble in ether

Ethyl Oleate is used in the following products:
-washing & cleaning products
-adhesives and sealants
-lubricants and greases
-polishes and waxes
-fertilisers
-plant protection products

Ethyl Oleate is used in plant protection products.
Ethyl Oleate is used for the manufacture of chemicals.

Ethyl Oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol.
Ethyl Oleate is a colorless oil although degraded samples can appear yellow.

Ethyl Oleate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of oleic acid with the hydroxy group of ethanol.
Ethyl Oleate, also known as ethyl oleic acid, belongs to the class of organic compounds known as fatty acid esters.

Oleic acid ethyl ester is a neutral, more lipid-soluble form of oleic acid.
Ethyl Oleate is used in metal surface treatment products
Ethyl Oleate is used in textile treatment products and dyes
Ethyl Oleate is used in pH regulators and water treatment products
Ethyl Oleate is used for the manufacture of leather or fur and chemicals.

Use and Occurrence:
Additive:
Ethyl Oleate is used by compounding pharmacies as a vehicle for intramuscular drug delivery, in some cases to prepare the daily doses of progesterone in support of pregnancy.
Ethyl Oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids.
Ethyl Oleate also finds use as a lubricant and a plasticizer.

Occurrence:
Ethyl Oleate has been identified as a primer pheromone in honeybees.

Precursor to other chemicals:
By the process of ethenolysis, the methyl ester of oleic acid, converts to 1-decene and methyl 9-decenoate:
CH3(CH2)7CH=CH(CH2)7CO2Me + CH2=CH2 → CH3(CH2)7CH=CH2 + MeO2C(CH2)7CH=CH2

Alternative Classes:
Carboxylic acid esters
Monocarboxylic acids and derivatives
Organic oxides
Hydrocarbon derivatives
Carbonyl compounds

Medical Aspects:
Ethyl Oleate is one of the fatty acid ethyl esters (FAEE) produced after ingestion of ethanol.

Ethyl Oleate is an ester of ethyl alcohol and oleic acid
Ethyl Oleate is also known as ethyl oleic acid

Ethyl Oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids.
Ethyl Oleate also finds use as a lubricant and a plasticizer.
Ethyl Oleate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of oleic acid with the hydroxy group of ethanol.

Ethyl Oleate has a role as a plant metabolite and an acaricide.
Ethyl Oleate derives from an oleic acid.

Ethyl Oleate belongs to the class of organic compounds known as fatty acid esters.
These are carboxylic ester derivatives of a fatty acid.

Substituents:
-Fatty acid ester
-Carboxylic acid ester
-Monocarboxylic acid or derivatives
-Carboxylic acid derivative
-Organic oxygen compound
-Organic oxide
-Hydrocarbon derivative
-Organooxygen compound
-Carbonyl group
-Aliphatic acyclic compound


Ethyl Oleate has been used in topical gel formulations, and in self-microemulsifying drug delivery systems for oral administration.
Ethyl Oleate is a suitable solvent for steroids and other lipophilic drugs.
Ethyl Oleate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of oleic acid with the hydroxy group of ethanol.
Ethyl Oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol.

Ethyl Oleate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of oleic acid with the hydroxy group of ethanol.
Ethyl Oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol.
Ethyl Oleate is the liquid lipid component in nanostructured lipid carriers (NLCs).

Ethyl Oleate is a glycol ether that is used as a solvent and in the manufacture of other chemicals.
Ethyl Oleate has been shown to have high affinity for proteins and glycosides.
Ethyl Oleate has been used as an analytical method to identify glycol ethers by using monoclonal antibodies.
The optimum extraction process for Ethyl Oleate is solid phase microextraction, which can be performed on either cellulose or polymeric beads.
Surface methodology can be used to study the interactions between Ethyl Oleate and rat liver microsomes, with sodium-dependent glucose as an example substrate.


PHYSICAL PROPERTIES:

-Molecular Weight: 310.5 g/mol

-XLogP3-AA: 8

-Exact Mass: 310.287180451 g/mol

-Monoisotopic Mass: 310.287180451 g/mol

-Topological Polar Surface Area: 26.3Ų

-Physical Description: Clear yellow liquid

-Color: Clear Yellow

-Form: Liquid

-Odour: Floral odor

-Solubility: insoluble in water

-Density: 0.868-0.873

-Refractive Index: 1.448-1.453

-Melting Point: -32 °C

-Boiling Point: 216-218 °C

-Flash Point: > 113 °C


Ethyl Oleate can be used as a starting material to synthesize stearic acid hydrazide intermediate, which can undergo intermolecular cyclization reaction with various aliphatic acids and aromatic acids to yield 1,3,4-oxadiazole derivatives.
Ethyl Oleate is also reduced to oleyl alcohol via Bouveault−Blanc reduction reaction.
Ethyl Oleate is used to prepare the oily phase of self-microemulsifying drug delivery system (SMEDDS) for tacrolimus

Ethyl Oleate has a role as a plant metabolite and an acaricide.
Ethyl Oleate derives from an oleic acid.
Ethyl Oleate is a natural product found in Hamamelis virginiana, Stachybotrys chartarum, and other organisms with data available.


CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 0

-Hydrogen Bond Acceptor Count: 2

-Rotatable Bond Count: 17

-Heavy Atom Count: 22

-Formal Charge: 0

-Complexity: 258

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0

-Defined Bond Stereocenter Count: 1

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 1

-Compound Is Canonicalized: Yes

-Chemical Classes: Other Classes -> Esters, Other


Ethyl Oleate (Oleic acid ethyl ester) is a fatty acid ester formed by the condensation of oleic acid and ethanol
Ethyl Oleate is usually used as a solvent for pharmaceutical drug preparations.

Ethyl Oleate is found in sweet marjoram.
Ethyl Oleate is a flavouring ingredient.

Ethyl Oleate is a fatty acid ester formed by the condensation of oleic acid and ethanol.
Ethyl Oleate is a colorless oil although degraded samples can appear yellow.
Ethyl Oleate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of oleic acid with the hydroxy group of ethanol.

Ethyl Oleate is the ester formed by the condensation of the fatty acid oleic acid and ethanol.
Ethyl Oleate is a colorless to light yellow liquid

Ethyl Oleate is produced by the body during ethanol intoxication.
Ethyl Oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids.
Ethyl Oleate also finds use as a lubricant and a plasticizer.

Ethyl Oleate belongs to the class of organic compounds known as fatty acid esters.
These are carboxylic ester derivatives of a fatty acid.

Ethyl Oleate is a fatty acid ester used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids
Ethyl Oleate is the ester formed by the condensation of the fatty acid oleic acid and ethanol.
Ethyl Oleate is a colorless to light yellow liquid.

Ethyl Oleate is used in the transport industry as a lubricant and as a plasticiser.
Ethyl Oleate is also used as a planting agent and for treating surfaces.

Ethyl Oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids.
Ethyl Oleate also finds use as a lubricant and a plasticizer.

Ethyl Oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids.
Ethyl Oleate also finds use as a lubricant and a plasticizer.

Ethyl Oleate is a pale yellow to almost colorless, mobile, oily liquid with a taste similar to olive oil and a slight odor that is not rancid.
Ethyl Oleate is described as consisting of esters of ethyl alcohol and high molecular weight fatty acids, principally oleic acid.

Ethyl Oleate may contain a suitable antioxidant.
Ethyl Oleate is a flavoring and fragrance agent.

Ethyl Oleate derives from an oleic acid.
Ethyl Oleate is a natural product found in Hamamelis virginiana, Stachybotrys chartarum, and other organisms with data available.

Ethyl Oleate is a flavoring and fragrance agent.
Ethyl Oleate was obtained by the hydrolysis of various animal and vegetable fats and oils

Ethyl Oleate is usually used to prepare the oily phase of self-microemulsifying drug delivery system (SMEDDS) for tacrolimus (Tac).
Ethyl Oleate is obtained by the hydrolysis of various animal and vegetable fats and oils.

Ethyl Oleate is a long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of oleic acid with the hydroxy group of ethanol.
Ethyl Oleate has a role as a plant metabolite and an acaricide.

Ethyl Oleate is functionally related to an oleic acid.
Ethyl Oleate is a colourless to pale yellow oily liquid that has a faint, floral note.

Ethyl Oleate is neutral and is a more lipid-soluble form of oleic acid.
The compound is one of the fatty acid ethyl esters that is generated after the breakdown of ethanol in the body.

Pharmaceutical Applications
Ethyl Oleate is primarily used as a vehicle in certain parenteral preparations intended for intramuscular administration.
Ethyl Oleate has also been used as a solvent for drugs formulated as biodegradable capsules for subdermal implantation) and in the preparation of microemulsions containing cyclosporinand norcantharidin.
Microemulsion formulations containing Ethyl Oleate have also been proposed for topical and ocular delivery, and for liver targeting following parenteral administration.
Ethyl Oleate has been used in topical gel formulations, and in self-microemulsifying drug delivery systems for oral administration.
Ethyl Oleate is a suitable solvent for steroids and other lipophilic drugs.
Ethyl Oleate's properties are similar to those of almond oil and peanut oil.
However, Ethyl Oleate has the advantage that it is less viscous than fixed oils and is more rapidly absorbed by body tissues.
Ethyl Oleate has also been evaluated as a vehicle for subcutaneous injection.

Ethyl Oleate has a floral odour
Ethyl Oleate has a role as a plant metabolite and an acaricide.

Ethyl Oleate is soluble in ether
Ethyl Oleate is used in the following products lubricants and greases

Ethyl Oleate is used for the manufacture of chemicals.
Ethyl Oleate is a colorless oil although degraded samples can appear yellow.

Ethyl Oleate is used in textile treatment products and dyes
Ethyl Oleate also finds use as a lubricant and a plasticizer.
Ethyl Oleate has been identified as a primer pheromone in honeybees.

Ethyl Oleate is also known as ethyl oleic acid
Ethyl Oleate is used as a solvent for pharmaceutical drug preparations involving lipophilic substances such as steroids.
Ethyl Oleate derives from an oleic acid.


SYNONYMS:

Ethyl Oleate
111-62-6
Oleic acid, ethyl ester
Ethyl cis-9-octadecenoate
ethyl (Z)-octadec-9-enoate
Oleic acid ethyl ester
9-Octadecenoic acid (Z)-, ethyl ester
ETHYLOLEATE
FEMA No. 2450
Ethyl Oleate
MFCD00009579
NSC-229428
ethyl (9Z)-octadec-9-enoate
DTXSID3047633
UNII-Z2Z439864Y
CHEBI:84940
(Z)-9-Octadecenoic acid ethyl ester
Ethyl Oleate (NF)
Z2Z439864Y
9-Octadecenoic acid, (Z)-, ethyl ester
Ethyl Oleate (natural)
Ethyl 9-octadecenoate, (Z)-
EINECS 203-889-5
NSC 229428
Ethyl 9-octadecenoate
9-Octadecenoic acid (9Z)-, ethyl ester
OLEATE, ETHYL
85049-36-1
AI3-00657
Ethyl Z-9-octadecenoate
Oleic acid ethyl
9-Octadecenoic acid, ethyl ester, (Z)-
Ethyl Oleate, NF
Ethyl Oleate, 98%
Oleic acid-ethyl ester
ethyl (9Z)-octadecenoate
SCHEMBL2797
CHEMBL2106289
DTXCID1027633
Ethyl (9Z)-9-octadecenoate #
Ethyl Oleate, natural, >=85%
Ethyl Oleate, analytical standard
HMS3650O15
Ethyl Oleate
HY-N7103
cis-9-Octadecenoic Acid ethyl ester
Tox21_303521
Ethyl Oleate, technical grade, 70%
NSC229428
s5367
AKOS025117011
CCG-267586
CS-W009922
NCGC00257457-01
AC-33783
CAS-111-62-6
O0054
O0143
D04090
EN300-1724742
A894703
SR-01000946820
Q6578680
SR-01000946820-1
Z2315574852
Ethyl Oleate
Ethyl Oleate
(Z)-Octadec-9-enoic Acid Ethyl Ester
Oleic acid-ethyl ester
(Z)-9-OCTADECENOIC ACID, ETHYL ESTER
9-OCTADECENOIC ACID (9Z)-, ETHYL ESTER
9-OCTADECENOIC ACID, ETHYL ESTER
9OCTADECENOIC ACID (Z), ETHYL ESTER
ETHYL ESTER 9-OCTADECENOIC ACID
ETHYL ESTER OLEIC ACID
Ethyl Oleate
OLEIC ACID, ETHYL ESTER
(Z)-9-Octadecenoic acid ethyl ester
9-Octadecenoic acid (Z)-, ethyl ester
Elaidic acid ethyl ester
Ethyl (9Z)-9-octadecenoate
Ethyl cis-9-octadecenoate
Ethyl Oleate
Ethyl oleic acid
Ethyl Z-9-octadecenoate
Oleic acid ethyl ester
crodamol EO
ethyl (9Z)-octadec-9-enoate
ethyl (Z)-9-octadecenoate
ethyl (Z)-octadec-9-enoate
(Z)-ethyl 9-octadecenoate
ethyl cis-9-octadecenoate
Ethyl Oleate synthetic
ethyloleate
9-octadecenoic acid (Z)-, ethyl ester
(9Z)-9-octadecenoic acid ethyl ester
(Z)-9-octadecenoic acid ethyl ester
9-octadecenoic acid, ethyl ester, (9Z)-
(Z)-oleic acid ethyl ester
(Z)-oleic acid, ethyl ester
(Z)-9-Octadecenoic Acid Ethyl Ester
111-62-6
203-889-5
9-Octadecenoic acid, ethyl ester, (9Z)-
9Z-octadecenoic acid, ethyl ester
Ethyl (9Z)-9-octadecenoate
Ethyl (9Z)-octadec-9-enoate
Ethyl cis-9-octadecenoate
Ethyl Oleate
Ethylis oleas
MFCD00009579 [MDL number]
Oleic Acid ethyl ester
Oleic acid, ethyl ester
RG3715000
(9Z)-9-Octadecenoic acid ethyl ester
(Z)-octadec-9-enoic acid ethyl ester
[111-62-6] [RN]
85049-36-1 [RN]
9-Octadecenoic acid (Z)-, ethyl ester
CIS-9-OCTADECENYL ACETATE
D04090
Elhyl oleate
ethyl (9Z)octadec-9-enoate
ethyl (9Z)-octadecenoate
ethyl (Z)-octadec-9-enoate
ethyl octadec-9-enoate
Ethyl Oleate (NF)
Ethyl Oleate(c18:1)
Ethyl Z-9-octadecenoate
ethyloleate
ETHYL PALMATE
ETHYL PALMITATE. N° CAS : 628-97-7. Nom INCI : ETHYL PALMITATE. Nom chimique : Ethyl palmitate. N° EINECS/ELINCS : 211-064-6. Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau: Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques. 211-064-6 [EINECS] 628-97-7 [RN] Ethyl Hexadecanoate Ethyl n-hexadecanoate Ethyl palmitate Ethylhexadecanoat Ethylpalmitat [German] Hexadecanoic acid ethyl ester Hexadecanoic acid, ethyl ester [ACD/Index Name] MFCD00008996 [MDL number] Palmitate d'éthyle [French] Palmitic acid ethyl ester palmitic acid, ethyl ester Palmitic acid, ethyl ester (8CI) [628-97-7] EINECS 211-064-6 Ethyl cetylate ethyl palmitate 97% ethyl palmitate 98% ethyl palmitate, ??? 95.0% ethyl palmitate, 97% ethyl palmitate/ethyl hexadecanoate(c16:0) Ethyl-?a?-Chloropropionate Ethylhexadecanoate Ethylpalmitate Hexadecanoic acid-ethyl ester Palmitic Acid ethyl ester|hexadecanoic acid, ethyl ester
ETHYL PALMITATE
ETHYL PHENYLACETATE. N° CAS : 101-97-3..Nom INCI : ETHYL PHENYLACETATE. Nom chimique : Ethyl phenylacetate. N° EINECS/ELINCS : 202-993-8. Ses fonctions (INCI): Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques
Ethyl Paraben
ethyl 4-hydroxybenzoate; benzoic acid, 4-hydroxy-, ethyl ester; 4- carbethoxyphenol; ethyl 4-hydroxybenzoate; ethylparaben ; ethyl-para-hydroxybenzoate CAS NO:120-47-8
ETHYL PARABEN
Chemical name Ethyl 4-Hydroxybenzoate INCI designation Ethylparaben Product properties *) Appearance (20°C): White, or almost white crystalline powder. Chemical and physical data Melting point: 115 - 118 oC Assayacc. BP/PH.Eur: 98.0 - 102.0 % IUPAC name Ethyl 4-hydroxybenzoate Other names Ethyl paraben; Ethyl parahydroxybenzoate; Ethyl para-hydroxybenzoate; Ethyl p-hydroxybenzoate; 4-Hydroxybenzoic acid ethyl ester Identifiers CAS Number: 120-47-8 Ethylparaben is an ethyl ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with ethanol, It has a role as an antimicrobial food preservative, an antifungal agent, a plant metabolite and a phytoestrogen. It is a paraben and an ethyl ester. Antimicrobial Preservative Used in Cosmetics and Personal Care. Uses Ethyl paraben is a broad spectrum antimicrobial agent designedfor preservation of a wide range of cosmetics, toiletries and topical pharmaceuticals. Ethyl paraben is suitable to preserve both rinse- off and leave- on formulations. Applications Typical use concentrations of Ethylparaben is 0.1 – 0.3 %. Combinations of p- Hydroxybenzoic acid esters, e.g. with Nipasol M, Nipagin M or Nipabutyl exhibit increased activity compared with individual esters. Incorporation Ethylparaben is freely soluble in most oils, waxes, fatty alcohols, but have relatively low solubility in water. The low aqueous solubility does not affect the microbiological efficacy of the esters. Most formulations requiring preservation contain a significant amount of water. This may mean that Ethylparaben cannot readily be added directly to the formulation. Other methods of incorporation are quite straightforward however, and are listed below. Ethyl paraben (ethyl para-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid. Its formula is HO-C6H4-CO-O-CH2CH3. It is a member of the class of compounds known as parabens. It is used as an antifungal preservative. As a food additive, it has E number E214. Sodium ethyl para-hydroxybenzoate, the sodium salt of ethylparaben, has the same uses and is given the E number E215. Dissolving in water The solubility of Ethylparaben increases greatly as the temperature of the water rises. Therefore a concentrate may be made up by heating an appropriate quantity of water to 60- 100 °C prior to addition of Ethylparaben. This concentrate may then be added to the formulation, provided that the ester concentration does not exceed its solubility in the formulation at normal ambient temperatures. Dissolving in organic solvents Ethylparaben is readily soluble in polar organic solvents. Where such a solvent is already part of a formulation an Ethylparaben concentrate may be made up prior to addition. If a suitable solvent is not already part of the formulation,a highly concentrated solution may be madeup e.g. 32 % in Ethanol, which would give insignificant residual levels of ethanol in the end product. Solubilisation in oils, emulsifiers etc. Ethylparaben is readily soluble in lipophilic ingredients and may be introduced to a formulation by adding to the oil phase with some warming before any emulsification stage. In multiphase systems, such as emulsions, it is often advisable to use a combination of aqueous dissolution with either of the other methods to ensure adequate preservation. The ester may be incorporated in the water to its maximum solubility and any further quantities may be dissolved in the oil phase, or solvent, as appropriate. pH stability Ethylparaben remains fully stable over a wide pH range from 4- 8. In general the lower the pH of the formulation, the more active is Ethylparaben. That can result in a lower use concentration when the pH of the formulation is more acidic. Temperature stability Ethylparaben is stable up to 80 °C Solubility The solubility of Ethyl paraben in different solvents is illustrated in the following table. Solvent % (w/w) Water 10 °C 0.06 Water 25 °C 0.11 Water 80 °C 0.86 Water 100 °C 1.7 Acetone 46 Methanol 45 Ethanol 41 Propylene Glycol 20 Glycerol 0.5 Vegetable oils (arachis) 1.0 Liquid paraffin 0.025 Microbial Activity Ethylparaben exhibits microbiostatic activity against a wide range of bacteria, yeast and mould. This is illustrated by the following table which shows the minimum inhibitory concentration (MIC) of Ethylparaben against examples of different groups of microorganisms. Microorganisms MIC level (%) Gram Negative Bacteria Pseudomonas aeruginosa 0.10 Escherichia coli 0.05 Klebsiella aerogenes 0.05 Klebsiella pneumoniae 0.05 Serratia marcescens 0.05 Proteus vulgaris 0.06 Salmonella enteritidis 0.05 Salmonella typhi 0.10 Microorganisms MIC level (%) Gram Positive Bacteria Stpahylococcus aureus 0.07 Streptococcus haemolyticus 0.06 Bacillus cereus 0.025 Bacillus subtilis 0.10 Lactobacillus buchneri 0.06 Yeasts Candida albicans 0.07 Saccharomyces cerevisiae 0.05 Molds Aspergillus niger 0.04 Penicillium digitatum 0.025 Rhizopus nigricans 0.025 Ethylparaben ETHYL 4-HYDROXYBENZOATE 120-47-8 Ethyl paraben Ethyl p-hydroxybenzoate Mycocten 4-Hydroxybenzoic acid ethyl ester Ethyl parasept Ethyl parahydroxybenzoate Easeptol Ethyl butex p-Hydroxybenzoic acid ethyl ester Tegosept E Napagin A Ethylparaben Nipazin A Solbrol A Sobrol A Benzoic acid, 4-hydroxy-, ethyl ester p-Carbethoxyphenol Aseptoform E Mekkings E Aseptin A Bonomold OE Ethyl p-oxybenzoate Ethyl-p-hydroxybenzoate Ethyl-4-hydroxybenzoate Ethyl para-hydroxybenzoate p-Oxybenzoesaeureaethylester 4-Hydroxy-benzoic acid ethyl ester 4-Carbethoxyphenol NSC 23514 p-Hydroxybenzoate ethyl ester Ethylparaben [NF] 9001-05-2 UNII-14255EXE39 4-Hydroxybenzoic acid, ethyl ester 4-(Ethoxycarbonyl)phenol Para-hydroxybenzoic acid ethyl ester Ethylester kyseliny p-hydroxybenzoove MFCD00002353 Benzoic acid, p-hydroxy-, ethyl ester Ester etylowykwasu p-hydroksybenzoesowego E214 Ethylparaben (NF) 14255EXE39 NCGC00160654-01 Carbethoxyphenol DSSTox_CID_2528 WLN: QR DVO2 DSSTox_RID_76615 DSSTox_GSID_22528 Ethyl 4-hydroxybenzoate, 99% Caswell No. 447 p-Hydroxybenzoic acid, ethyl ester CAS-120-47-8 HSDB 938 EINECS 204-399-4 p-Oxybenzoesaeureaethylester [German] EPA Pesticide Chemical Code 061202 BRN 1101972 Ethyl chemosept AI3-30960 Aseptine a Nipagina A Ethylester kyseliny p-hydroxybenzoove [Czech] Ester etylowykwasu p-hydroksybenzoesowego [Polish] PubChem20417 Ethyl 4-hydroxy-benzoate Ethyl 4-hydroxyl-benzoate Ethylparaben, INN, USAN ACMC-209a7k bmse010255 EC 204-399-4 p-Hydroxybenzoic ethyl ester SCHEMBL28368 4-10-00-00367 (Beilstein Handbook Reference) Ethyl 4-Hydroxybenzoate,(S) BIDD:ER0023 CHEMBL15841 Ethyl parahydroxybenzoate (TN) ZINC1392 DTXSID9022528 ethyl 4-hydroxybenzenecarboxylate CHEBI:31575 4-hydroxybenzoic acid-ethyl ester NSC8510 Ethyl parahydroxybenzoate (JP17) ETHYL PARA HYDROXY BENZOATE HMS2091E17 Parahydroxybenzoic acid ethyl ester Pharmakon1600-01400151 4-hydroxy benzoic acid ethyl ester HY-B0934 NSC-8510 NSC23514 4-(Dimethylamino)benzenesulfonicacid Tox21_111961 Tox21_300335 ANW-17502 BBL012166 BDBM50428380 NSC-23514 NSC755851 s4525 SBB038536 STK070911 AKOS000120512 Tox21_111961_1 CCG-213682 CS-4403 DB13628 MCULE-4906467392 NSC-755851 NCGC00160654-02NCGC00160654-03 NCGC00160654-04 NCGC00160654-06 NCGC00254462-01 AC-11586 AK-49315 AS-11988 NCI60_041866 SC-22680 SC-46755 SBI-0206674.P002 E-214 E0884 FT-0623514 FT-0626357 FT-0668364 ST50210582 4-FLUORO-3-METHYLPHENYLMAGNESIUMBROMIDE A16012 A18133 D01647 Ethyl 4-hydroxybenzoate, ReagentPlus(R), 99% M-3934 AB00375765_03 Q229976 SR-05000001552 SR-05000001552-1 W-108475 BRD-K02464583-001-01-4 Ethyl 4-hydroxybenzoate, SAJ first grade, >=99.0% Ethyl 4-hydroxybenzoate, Vetec(TM) reagent grade, 99% Ethylparaben, certified reference material, TraceCERT(R) F0728-0009 UNII-AZF98361GV component NUVBSKCKDOMJSU-UHFFFAOYSA-N 4-Hydroxybenzoic acid-ethyl ester 1000 microg/mL in Acetonitrile Ethylparaben, United States Pharmacopeia (USP) Reference Standard Ethyl parahydroxybenzoate, European Pharmacopoeia (EP) Reference Standard Ethylparaben, Pharmaceutical Secondary Standard; Certified Reference Material E4B ethylparaben Rating: GOOD Categories: Preservatives Parabens are a group of controversial preservatives that include butylparaben, isobutylparaben, propylparaben, methylparaben, and ethylparaben. All of these were at one time the most widely used group of preservatives used in cosmetics. Parabens were so popular because of their gentle, non-sensitizing, and highly effective profile in comparison to other preservatives but also because they were derived naturally from plants, a rare phenomenon for a preservative. Parabens are found in plants in the form of p-hydroxybenzoic acid (PHBA), a chemical that breaks down to become parabens for a plants own protection. Over the past 10 years parabens have become criticized and condemned for use in cosmetics due to their alleged relation to health concerns affecting women and men. The research about parabens is conflicting and polarizing. Some research indicates they are safe as used in cosmetics and are preferred over other preservatives to keep a formula stable. These studies also showed parabens did not have any effect when compared to natural hormones in the body. However, other research has concluded they are indeed problematic: Some studies determined a 100% concentration of parabens caused skin samples (meaning not intact skin on a person) to break down. However, these studies don’t apply to the tiny amount (1% or less) of parabens typically used in cosmetics. In low amounts, parabens were not shown to harm skin; in fact, they offer a benefit due to their ability to thwart the growth of mold, fungi, and harmful pathogens. Other studies casting parabens in a negative light were based on force-feeding them to rats, a practice that is not only cruel but unrelated to what happens when parabens are applied to skin. There are studies indicating absorption of parabens through skin associated with application of skincare products, but those studies did not take into consideration that parabens are still used as food-grade preservatives or found naturally in plants and that could have been the source not the cosmetics. We also looked at studies showing other questionable effects but those were done in vitro meaning in a petri dish or, again, animal studies in species whose biologic makeup does not closely relate to people. Chemical Properties white crystalline powder Chemical Properties Ethylparaben occurs as a white, odorless or almost odorless, crystalline powder. Uses An antimicrobial Uses bronchodilator, tocolytic Uses Preservative for pharmaceuticals. Production Methods Ethylparaben is prepared by the esterification of p-hydroxybenzoic acid with ethanol (95%). Synthesis Reference(s) The Journal of Organic Chemistry, 39, p. 3343, 1974 DOI: 10.1021/jo00937a007 Pharmaceutical Applications Ethylparaben is widely used as an antimicrobial preservative in cosmetics,food products, and pharmaceutical formulations. It may be used either alone or in combination with other paraben esters or with other antimicrobial agents. In cosmetics it is one of the most frequently used preservatives. The parabens are effective over a wide pH range and have a broad spectrum of antimicrobial activity, although they are most effective against yeasts and molds. Owing to the poor solubility of the parabens, paraben salts, particularly the sodium salt, are frequently used. However, this may cause the pH of poorly buffered formulations to become more alkaline. Contact allergens This substance is one of the parabens family. Parabens are esters formed by p-hydroxybenzoic acid and an alcohol. They are largely used as biocides in cosmetics and toiletries, medicaments, or food. They have synergistic power with other biocides. Parabens can induce allergic contact dermatitis, mainly in chronic dermatitis and wounded skin. Safety Ethylparaben and other parabens are widely used as antimicrobial preservatives in cosmetics, food products, and oral and topical pharmaceutical formulations. Systemically, no adverse reactions to parabens have been reported, although they have been associated with hypersensitivity reactions. Parabens, in vivo, have also been reported to exhibit estrogenic responses in fish.(10) The WHO has set an estimated total acceptable daily intake for methyl-, ethyl-, and propylparabens at up to 10 mg/kg body-weight. LD50 (mouse, IP): 0.52 g/kg LD50 (mouse, oral): 3.0 g/kg storage Aqueous ethyl paraben solutions at pH 3–6 can be sterilized by autoclaving, without decomposition. At pH 3–6, aqueous solutions are stable (less than 10% decomposition) for up to about 4 years at room temperature, while solutions at pH 8 or above are subject to rapid hydrolysis (10% or more after about 60 days at room temperature). Ethylparaben should be stored in a well-closed container in a cool, dry place. Incompatibilities The antimicrobial properties of ethyl paraben are considerably reduced in the presence of nonionic surfactants as a result of micellization. Absorption of ethylparaben by plastics has not been reported, although it appears probable given the behavior of other parabens. Ethylparaben is coabsorbed on silica in the presence of ethoxylated phenols. Yellow iron oxide, ultramarine blue, and aluminum silicate extensively absorb ethylparaben in simple aqueous systems, thus reducing preservative efficacy. Ethyl paraben is discolored in the presence of iron and is subject to hydrolysis by weak alkalis and strong acids. Regulatory Status Accepted as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral, otic, and topical preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients. • 4-Carbethoxyphenol • nipaginaa • Nipazin A • nipazina • Para-hydroxybenzoic acid ethyl ester • p-Carbethoxyphenol • p-Hydroxybenzoic ethyl ester • p-hydroxy-benzoicaciethylester • p-hydroxybenzoicethylester • p-Oxybenzoesaeureaethylester • Sobrol A • Solbrol A • solbrola • Tegosept E • ETHYLPARABEN,NF • 4-HYDROXYBENZOICACIDETHYLESTER(ETHYLPARABEN) • PARABEN,ETHYL • Ethyl-4-hydroxybenzoat • Ethyl P-Hdroxybenzoate • ETHYLP-HYDROXYBENZOATE/EASEPTOL • ETHYL-4-HYDROXYBENZOATE WITH HPLC • ETHYLPARABEN (ETHYL 4-HYDROXYBENZOATE) • 4-Hydroxybenzoic acid ethyl • Aceptin A • Sorbrol A • Ethyl 4-hydroxybenzoate,99% • Ethyl p-Hydrobenzoate • 2-Ethyl-4-hydroxy-benzoicacid • Ethyl-p-hydroxybenzoate 5g [120-47-8] • Ethylparaben (200 mg) • Of ethyl • Of ethyl (Ethylparaben) • Ethyl cheMosept • Solbro A • Ethyl 4-Hydroxybenzoate [for BiocheMical Research] • Ethyl Paraben (EP) • Ethyl p-Hydroxybenzoate (Ethylparaben) • Ethyl 4-Hydroxybenzoate,(S) • ETHYL 4-HYDROXYBENZOATE / ETHYLPARABEN • Ethyl 4-hydroxybenzoate, 99% 100GR • Easeptol • Ester etylowykwasu p-hydroksybenzoesowego • esteretylowykwasup-hydroksybenzoesowego • ethvlparaben • Ethyl • Ethyl para-hydroxybenzoate • Ethyl p-oxybenzoate • Ethylester kyseliny p-hydroxybenzoove • ethylesterkyselinyp-hydroxybenzoove • ethylhydroxybenzoate • Mekkings E • NSC 23514 • Ethylparaben 4-Hydroxybenzoic Acid Ethyl Ester • Methylparaben Impurity 1(Ethylparaben) • Compound sodium acetate neper gold • Methyldopa impurity 1 • ETHYL 4-HYDROXYBENZOATE • ethyl butex 120-47-8 [RN] 14255EXE39 204-399-4 [EINECS] 2-Ethoxybenzoic acid [ACD/IUPAC Name] 4-Hydroxybenzoate d'éthyle [French] [ACD/IUPAC Name] 4-hydroxybenzoic acid ethyl ester 4-Hydroxybenzoic acid, ethyl ester Benzoic acid, 4-hydroxy-, ethyl ester [ACD/Index Name] DH2190000 Ethyl 4-hydroxybenzoate [ACD/IUPAC Name] Ethyl chemosept [Trade name] ETHYL PARABEN Ethyl parahydroxybenzoate [JP15] Ethyl parasept [Trade name] ethyl p-hydroxybenzoate Ethyl p-oxybenzoate Ethyl-4-hydroxybenzoat [German] [ACD/IUPAC Name] Ethylparaben [NF] [USAN] [Wiki] etilparabeno [Portuguese] Nipagina A [Trade name] p-Oxybenzoesaurepropylester [German] Propylester kyseliny p-hydroxybenzoove [Czech] Solbrol A [Trade name] 02/05/9001 05/02/9001 1-(4-Hydroxyphenyl)-2-methoxyethanone [ACD/IUPAC Name] 1219795-53-5 [RN] 126070-21-1 [RN] 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide 4-(Ethoxycarbonyl)phenol 4-10-00-00367 (Beilstein Handbook Reference) [Beilstein] 4-Carbethoxyphenol 4-Hydroxy-benzoic acid ethyl ester 4-hydroxybenzoic acid ethyl ester,99% 4-Hydroxybenzoic acid ethylester 4-Hydroxybenzoic acid-ethyl ester 4-Hydroxybenzoic acid-ethyl ester 1000 µg/mL in Acetonitrile 59593-07-6 [RN] 85403-59-4 [RN] 9001-05-2 [RN] 94-13-3 [RN] Aseptin A Aseptine A Aseptoform E Benzoic acid, p-hydroxy-, ethyl ester Bonomold OE Bonomold OP Carbethoxyphenol CATALASE catalase from beef liver 2-5 ku/mg protein catalase from bovine liver catalase, lyophilized Chemocide pk E214 E-214 E4B Easeptol EINECS 202-307-7 EINECS 204-399-4 Ester etylowykwasu p-hydroksybenzoesowego Ester etylowykwasu p-hydroksybenzoesowego [Polish] ethyl 4-hydroxy-benzoate ethyl 4-hydroxybenzoate (en) ethyl 4-hydroxybenzoate 99% ethyl 4-hydroxybenzoate, ??? 99.0% ethyl 4-hydroxybenzoate, 99% ethyl 4-hydroxybenzoate-0.99mg/ml u=2% ??????????????? ethyl 4-hydroxybenzoate-ar Ethyl butex Ethyl hydroxybenzoate ETHYL PARA HYDROXY BENZOATE Ethyl Paraben? Ethyl paraben|4-hydroxybenzoic acid ethyl ester|4-(Ethoxycarbonyl)phenol Ethyl Paraben-d4 Ethyl para-hydroxybenzoate Ethyl parahydroxybenzoate (JP15) Ethyl parahydroxybenzoate (TN) Ethyl parahydroxybenzoate;Ethyl 4-hydroxybenzoate ethyl p-hydroxybenzoate 99% ethyl p-hydroxybenzoate standard ethyl4-hydroxybenzoate Ethyl-4-hydroxybenzoate ETHYL-4-HYDROXYBENZOATE with HPLC Ethylester kyseliny p-hydroxybenzoove Ethylester kyseliny p-hydroxybenzoove [Czech] Ethylparaben (NF) Ethylparaben, INN, USAN ETHYLPARABEN|ETHYL 4-HYDROXYBENZOATE ethyl-p-hydroxybenzoate Ethylp-hydroxybenzoate http:////www.amadischem.com/proen/606787/ http://en.atomaxchem.com/120-47-8.html https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:31575 Keloform Mekkings E MFCD00081483 Mycocten Napagin A NCGC00160654-01 NCGC00160654-02 Ethylparaben Nipagin P NIPASEPT Nipasol Nipasol M [Trade name] Nipasol P Nipazin A Nipazol Paraben [Wiki] Para-hydroxybenzoic acid ethyl ester Parasept Paseptol p-Carbethoxyphenol PFI-1 Pharmakon1600-01400151 p-Hydroxybenzoate ethyl ester p-Hydroxybenzoic acid ethyl ester p-Hydroxybenzoic acid, ethyl ester P-HYDROXYBENZOIC ACID,ETHYL ESTER P-Hydroxybenzoic ethyl ester p-Hydroxypropyl benzoate p-Oxybenzoesaeureaethylester p-Oxybenzoesaeureaethylester [German] Preserval P Propagin Protaben P Pulvis conservans Pulvis conservans (VAN) QR DVO3 [WLN] Sobrol A Solbrol P [Trade name] ST5210582 Tegosept E UNII:14255EXE39 UNII-14255EXE39 UNII-AZF98361GV WLN: QR DVO2 Ethylparaben * A preservative found in skin care products, often used to treat dry skin through essential oils such as eucalyptus and primrose oil * Read the following TIA articles concerning ethylparaben and its link to cancer: Preservatives and Parabens and Are They Safe? and What Is It: Estrogen in my Shampoo Ethylparaben is a paraben and preservative found in many skin care products, ranging from skin cream to body lotion to deodorant. It can be found in essential oils used to treat dry skin and in primrose oil serving as an anti-septic. Although parabens are generally considered safe when used in low percentages (.04% - .08%), a study claimed to have found a link between parabens and breast cancer. According to the Cosmetic Ingredient Review (CIR) Expert Panel, however, "the available acute, subchronic, and chronic toxicity tests, using a range of exposure routes, demonstrate a low order of parabens' toxicity at concentrations that would be used in cosmetics" (source). After testing different levels of exposure to parabens in women, men, and children, the CIR Expert Panel found that these "determinations are conservative and likely represent an overestimate of the possibility of an adverse effect (e.g., use concentrations may be lower, penetration may be less) and support the safety of cosmetic products in which parabens preservatives are used." * Ethylparaben is a preservative found in skin care products, often used to treat dry skin through essential oils such as eucalyptus and primrose oil * Read the following TIA articles concerning ethylparaben and its link to cancer: Preservatives and Parabens and Are They Safe? and What Is It: Estrogen in my Shampoo Functions: Ethylparaben is a paraben and preservative found in many skin care products, ranging from skin cream to body lotion to deodorant. It can be found in essential oils used to treat dry skin and in primrose oil serving as an anti-septic. Although parabens are generally considered safe when used in low percentages (.04% - .08%), a study claimed to have found a link between parabens and breast cancer. According to the Cosmetic Ingredient Review (CIR) Expert Panel, however, "the available acute, subchronic, and chronic toxicity tests, using a range of exposure routes, demonstrate a low order of parabens' toxicity at concentrations that would be used in cosmetics" (source). After testing different levels of exposure to parabens in women, men, and children, the CIR Expert Panel found that these "determinations are conservative and likely represent an overestimate of the possibility of an adverse effect (e.g., use concentrations may be lower, penetration may be less) and support the safety of cosmetic products in which parabens preservatives are used." Ultimately, the cosmetics industry has found the low levels of parabens in cosmetics to be safe and the connection between parabens and breast cancer to be weak. The FDA finds that although parabens can mimic estrogen, the actual effects of this low level of activity on the body do not cause cancer in a higher incidence than naturally occurring estrogen. Nonetheless, many paraben-free products are being created to avoid the possible dangers of ethylparaben and other paraben-based preservatives. Roles Classification Biological Role(s): antimicrobial food preservative A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299). antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. phytoestrogen Any compound produced by a plant that happens to have estrogenic activity. Application(s): antimicrobial food preservative A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299). Synonyms 4-hydroxybenzoic acid ethyl ester E-214 ChEBI E214 ChEBI ethyl p-hydroxybenzoate ethyl paraben Ethyl parahydroxybenzoate p-hydroxybenzoic acid ethyl ester p-Oxybenzoesaeureaethylester Deutsch Ethylparaben provides the good performance against Gram positive bacteria exhibited by all the parabens and has the same limitations regarding pH range (acidic only), system compatibility (avoid high levels of ethoxylates) and water solubility (limited). Ethylparaben has been used in combination with Propylparaben in oral preparations for controlling fermentative action. It can be used alone, but is generally used at 0.10 to 0.25% levels with other CoSepts as the antifungal portion of the preservative system. Use: Ethylparaben is mainly used as antiseptics in cosmetics, food and medicine. It is also can be used as feed preservatives and antiseptic for bacteria. Use: Preservative, Cosmetics, Feed, Pharmaceutical, Soft Drink, Alcohol Beverage, Beverage Powder, Fruit Juice, Puddings, Sauces, Baking Food, Sauage, Flavoring Agent. Synonyms: benzoic acid, 4-hydroxy-, ethyl ester 4- carbethoxyphenol p- carbethoxyphenol para- carbethoxyphenol ethyl 4-hydroxybenzoate ethyl p-hydroxybenzoate ethyl para-hydroxybenzoate ethyl-4-hydroxybenzoate ethyl-p-hydroxybenzoate ethyl-para-hydroxybenzoate ethylparaben 4- hydroxy-benzoic acid ethyl ester 4- hydroxybenzoic acid ethyl ester p- hydroxybenzoic acid ethyl ester para- hydroxybenzoic acid ethyl ester 4- hydroxybenzoic acid ethylester Other names: Benzoic acid, 4-hydroxy-, ethyl ester; Benzoic acid, p-hydroxy-, ethyl ester; p-Carbethoxyphenol; p-Hydroxybenzoate ethyl ester; p-Hydroxybenzoic acid ethyl ester; Aseptoform E; Bonomold OE; Easeptol; Ethyl p-hydroxybenzoate; Ethyl parasept; Ethyl Butex; Ethyl 4-hydroxybenzoate; Mycocten; Napagin A; Ethylparaben; Nipazin A; Sobrol A; Solbrol A; Tegosept E; 4-Hydroxybenzoic acid, ethyl ester; Ethyl para-hydroxybenzoate; Ester etylowykwasu p-hydroksybenzoesowego; Ethylester kyseliny p-hydroxybenzoove; Ethyl p-oxybenzoate; Nipagina A; p-Oxybenzoesaeureaethylester; 4-(Ethoxycarbonyl)phenol; 4-Carbethoxyphenol; Aseptin A; Aseptine A; Para-hydroxybenzoic acid ethyl ester; Mekkings E; NSC 23514 Ethylparaben (Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative and food additive. It is a standardized chemical allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. Ethylparaben is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative and food additive Storage instructions The product must be stored in tighly closed container in a cool, well- ventilated, dry place. Further information on handling, storage and dispatch isgiven in the EC safety data sheet. This information is based on our present state of knowledge and is intended to provide general notes on our products and their uses. It should not therefore be construed as guaranteeing specific properties of the products described on their suitability for a particular application. Any existing industrial property rights must be observed. The quality of our products is guaranteed under our General Conditions of Sale.
ETHYL PHENYLACETATE
ETHYL PYRROLIDONE. N° CAS : 2687-91-4. Nom INCI : ETHYL PYRROLIDONE. Nom chimique : 1-Ethylpyrrolidin-2-one; N-Ethylpyrrolidone. N° EINECS/ELINCS : 220-250-6 Solvant : Dissout d'autres substances
ETHYL PROXITOL GLYCOL ETHER
Ethyl PROXITOL Glycol Ether is a colorless, hygroscopic propylene glycol ether.
Ethyl PROXITOL Glycol Ether used in the surface coatings industry and printing inks and to regulate flow, leveling and coalescence.
Possesses good volatility, viscosity and solvent power.

CAS: 1569-02-4
MF: C5H12O2
MW: 104.15
EINECS: 216-374-5

Ethyl PROXITOL Glycol Ether can be used as a coupling agent.
Ethyl PROXITOL Glycol Ether used in adhesives.
Ethyl PROXITOL Glycol Ether is a colourless, hygroscopic solvent with a volatility, viscosity and solvent power similar to those of ethylene oxide-based glycol ethers.
Ethyl PROXITOL Glycol Ether (also known as propylene glycol ether; Arcosolv PE; ethyl proxitol; and propylene glycol monoethyl ether) is a clear liquid that has a characteristic ether-like odour.
Ethyl PROXITOL Glycol Ether has the formula C5H12O2 and it is miscible with water, is hygroscopic, and it also provides good solvency for a wide variety of substances, including resins, inks, and adhesives.

Ethyl PROXITOL Glycol Ether is a clear liquid that has a characteristic ether-like odor.
Ethyl PROXITOL Glycol Ether is miscible with water, is hygroscopic, and it also provides good solvency for a wide variety of substances, including resins, inks, and adhesives.
Ethyl PROXITOL Glycol Ether appears as a colorless liquid.
Flash point near 89 °F.
Less dense than water.
Contact irritates skin, eyes and mucous membranes.
Prolonged exposure to vapors may cause coughing, shortness of breath, dizziness and intoxication.
Vapors heavier than air.
Ethyl PROXITOL Glycol Ether used as a solvent and as an antifreeze agent.

Ethyl PROXITOL Glycol Ether is used in a range of industrial, professional, and consumer applications as it provides good solvency due to its’ bi-functional nature.
Ethyl PROXITOL Glycol Ether is miscible with both polar and non-polar substances and is an effective solvent for a wide variety of resins, which include epoxies, acrylic, alkyds, polyesters, nitrocellulose, and polyurethanes.
Ethyl PROXITOL Glycol Ether also provides low toxicity and this is another property which is valued by the users.

Ethyl PROXITOL Glycol Ether is employed mainly in the surface coating and printing industries as it can regulate the flow, levelling, and coalescence of both surface coatings (including water-based paints), and of flexographic printing inks.
Ethyl PROXITOL Glycol Ether is also utilised as a chemical intermediate in the production of agro-chemicals and in the production of de-icing/anti-icing formulations.
Ethyl PROXITOL Glycol Ether is also utilised in the cleaning industry where it provides cleaning formulations with surface tension reduction, a fast evaporation rate, and low toxicity.

Ethyl PROXITOL Glycol Ether Chemical Properties
Melting point: -100 °C
Boiling point: 132 °C
Density: 0.897
Vapor pressure: 10hPa at 23.85℃
Refractive index: 1.405-1.409
Fp: 42 °C
Storage temp.: 2-8°C
Solubility: Chloroform (Sparingly), Ethyl Acetate (Slightly)
Form: Liquid
pKa: 14.51±0.20(Predicted)
Specific Gravity: 0.896
Color: Colorless
Odor: Mild
Water Solubility: soluble
Exposure limits ACGIH: TWA 50 ppm; STEL 200 ppm (Skin)
LogP: 0 at 20℃
CAS DataBase Reference: 1569-02-4(CAS DataBase Reference)
NIST Chemistry Reference: Ethyl PROXITOL Glycol Ether (1569-02-4)
EPA Substance Registry System: Ethyl PROXITOL Glycol Ether (1569-02-4)

Uses
Ethyl PROXITOL Glycol Ether is used as a solvent for a wide variety of resins such as epoxies, acrylic, alkyds, polyesters, nitrocellulose, and polyurethanes.
Ethyl PROXITOL Glycol Ether is also used in the surface coating and printing industries, thereby it regulate the flow, levelling, and coalescence of both surface coatings.
Ethyl PROXITOL Glycol Ether acts as an intermediate in the production of agro-chemicals and de-icing, and anti-icing formulations.
Ethyl PROXITOL Glycol Ether finds application as to make cleaning products, as grease and paint remover.

Synonyms
1-Methoxy-2-propanol
107-98-2
1-Methoxypropan-2-ol
Methoxyisopropanol
PGME
2-Propanol, 1-methoxy-
Closol
Propylene glycol monomethyl ether
Dowtherm 209
1-Methoxy-2-hydroxypropane
Propasol solvent M
Dowanol 33B
PROPYLENE GLYCOL METHYL ETHER
2-Methoxy-1-methylethanol
Methyl proxitol
2-Propanol, methoxy-
Propylene glycol 1-methyl ether
Ucar Solvent LM (Obs.)
NSC 2409
Dowanol-33B
HSDB 1016
1-methoxy-propan-2-ol
EINECS 203-539-1
UN3092
BRN 1731270
UNII-74Z7JO8V3U
.alpha.-Propylene glycol monomethyl ether
AI3-15573
74Z7JO8V3U
Propyleneglycol monomethyl ether
DTXSID8024284
NSC-2409
EC 203-539-1
3-01-00-02146 (Beilstein Handbook Reference)
DTXCID804284
CAS-107-98-2
propyleneglycol monomethylether
Glycol ether pm
Ucar solvent lm
Solvent PM
Gylcol Ether PM
Icinol PM
methoxy isopropanol
Methoxy-2-propanol
MFCD00004537
1-methoxypropanol-2
1-Metoxipropan-2-ol
1-Metoksy-2-propanol
PME (CHRIS Code)
3-methoxy-propan-2-ol
Propan-1-methoxy-2-ol
2-Propanol, 1-metoxi-
rac-1-methoxy-2-propanol
1- methoxypropan- 2- ol
1,2-PROPYLENE GLYCOL 1-MONOMETHYL ETHER
2-methoxy-1-methyl ethanol
Propan-2-ol, 1-methoxy-
propylene glycol monomethylether
1-Methoxy-2-propanol, 98%
1-Methoxy-2-propanol (PGME)
Methoxypropanol, .alpha. isomer
(+/-)-1-methoxy-2-propanol
1 - methoxypropan - 2 - ol
CHEMBL3186306
METHOXYISOPROPANOL [INCI]
NSC2409
WLN: QY1 & 1O1
propylene glycol mono methyl ether
(+/-)2-methoxy-1-methylethanol
Propylene Glycol 1-Monomethyl Ether
Tox21_201803
Tox21_303269
LS-444
NA3092
1-Methoxy-2-propanol, >=99.5%
AKOS009158246
SB44649
SB44662
NCGC00249123-01
NCGC00256978-01
NCGC00259352-01
Propylene glycol monomethyl ether (PGME)
1-METHOXY-2-HYDROXYPROPANE [HSDB]
1-Methoxy-2-propanol, analytical standard
Propylene Glycol Methyl Ether Reagent Grade
FT-0608005
FT-0647598
FT-0654880
FT-0655258
M0126
EN300-73396
E72455
PROPYLENE GLYCOL MONOMETHYL ETHER, ALPHA
1-Methoxy-2-propanol [UN3092] [Flammable liquid]
Q1884806
1-Methoxy-2-propanol [UN3092] [Flammable liquid]
Z825742124
Propylene glycol monomethyl ether; (UCAR TRIOL HG-170)
Propylene glycol monomethyl ether; (UCAR TRIOL HG-170)
ETHYL PYRROLIDONE
ETHYL SALICYLATE, N° CAS : 118-61-6, Nom INCI : ETHYL SALICYLATE, Nom chimique : Ethyl 2-Hydroxybenzoate, N° EINECS/ELINCS : 204-265-5. Ses fonctions (INCI). Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques
ETHYL SALICYLATE
ETHYL STEARATE, N° CAS : 111-61-5, Nom INCI : ETHYL STEARATE, Nom chimique : Ethyl stearate, N° EINECS/ELINCS : 203-887-4, Ses fonctions (INCI), Emollient : Adoucit et assouplit la peau. Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques
Ethyl stearate
ETHYL TOSYLAMIDE N° CAS : 80-39-7 / 1077-56-1 Nom INCI : ETHYL TOSYLAMIDE Nom chimique : N-Ethyltoluene-2-sulphonamide N° EINECS/ELINCS : 201-275-1 / 214-073-3 Classification : Règlementé Ses fonctions (INCI) Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles Agent plastifiant : Adoucit et rend souple une autre substance qui autrement ne pourrait pas être facilement déformée, dispersée ou être travaillée
ETHYL TOSYLAMIDE
ETHYL VANILLIN, N° CAS : 121-32-4. Nom INCI : ETHYL VANILLIN, Nom chimique : 3-Ethoxy-4-hydroxybenzaldehyde, N° EINECS/ELINCS : 204-464-7. Ses fonctions (INCI): Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit. Agent apaisant : Aide à alléger l'inconfort de la peau ou du cuir chevelu
ETHYL TRIGLYCOL
Ethyl triglycol, also known as 2-(2-(2-ethoxyethoxy)ethoxy)ethanol, is a chemical compound with the molecular formula C6H14O4.
Ethyl triglycol is an ethylene glycol ether and is part of the glycol ether family.
Ethyl triglycol is commonly used as a solvent and coalescing agent in various industrial and commercial applications, including coatings, paints, and cleaning products.

CAS Number: 112-50-5
EC Number: 204-014-3



APPLICATIONS


Ethyl triglycol is widely used as a coalescing agent in water-based paints and coatings.
Ethyl triglycol enhances the film formation of latex paints, improving adhesion and durability.

Ethyl triglycol is essential in architectural coatings for creating smooth and even surfaces.
Ethyl triglycol reduces the drying time of paints and coatings, facilitating quicker project completion.

In the chemical industry, it serves as a versatile solvent for various chemical reactions and formulations.
Ethyl triglycol is used in the production of industrial and household cleaning products.
Ethyl triglycol aids in the removal of grease, oils, and stains in cleaning solutions.

Ethyl triglycol is employed in the formulation of inkjet printer inks, enhancing print quality.
Ethyl triglycol is found in makeup removers and facial cleansers in the cosmetics industry.
Ethyl triglycol acts as a wetting and leveling agent in ink and coating formulations.

Ethyl triglycol helps prevent defects like craters and pinholes in coatings.
Ethyl triglycol is used as a coalescing agent in adhesives and sealants, improving their performance.
Ethyl triglycol is a versatile component in the production of fragrances and perfumes.
Ethyl triglycol serves as a coupling agent in pesticide formulations, improving the even distribution of active ingredients.

Ethyl triglycol is utilized in the creation of industrial and institutional cleaning products.
Ethyl triglycol is an essential ingredient in rust removers, aiding in the removal of rust from various surfaces.
Ethyl triglycol is employed in the formulation of heat transfer fluids, contributing to efficient heat exchange.

Ethyl triglycol can be found in specialty lubricants, enhancing their performance in various applications.
Ethyl triglycol serves as a co-solvent in the production of household and industrial detergents.
Ethyl triglycol is used in the formulation of sealants for construction and automotive applications.

Ethyl triglycol is employed as a dispersant in crop protection products, enhancing their efficacy.
Ethyl triglycol contributes to the formulation of metalworking fluids, improving cutting and grinding operations.

Ethyl triglycol is used as a plasticizer in the plastic and rubber manufacturing industry.
Ethyl triglycol can be found in specialty coatings for medical devices, providing biocompatibility and durability.
Ethyl triglycol is utilized in the formulation of printing inks, enabling high-quality prints on various substrates.

Ethyl triglycol is used in the formulation of screen printing inks, where it helps control ink viscosity and improve adhesion to substrates.
In the construction industry, it can be found in concrete admixtures to enhance workability and reduce water requirements.
Ethyl triglycol is used as a diluent in the production of epoxy resins and coatings, contributing to their flow and leveling properties.
Ethyl triglycol can be employed as a carrier solvent in the formulation of air fresheners and deodorizers for household and industrial use.

Ethyl triglycol is used as a parting compound in the foundry industry to aid in the release of castings from molds.
In the oil and gas sector, it is present in oilfield chemicals used for drilling, hydraulic fracturing, and oil production operations.
Ethyl triglycol is utilized in the formulation of cleaning products, including ink removers and adhesive solvents.

Ethyl triglycol is found in printing inks, contributing to their adhesion and print quality, especially in flexographic and gravure printing.
Ethyl triglycol is employed in the cosmetics industry, where it can be found in makeup removers, cleansing lotions, and personal care products.
Ethyl triglycol serves as a viscosity modifier in the production of gel-based personal care and cosmetic items.

In agriculture, Ethyl triglycol is used in foliar sprays and crop protection products to enhance adhesion and dispersion of agrochemicals.
Ethyl triglycol is utilized in the formulation of agricultural adjuvants to improve the effectiveness of pesticides and herbicides.

Ethyl triglycol can be found in automotive appearance products such as tire shines and dashboard protectants.
In the plastics industry, it serves as a plasticizer, enhancing the flexibility and processability of plastics.

Ethyl triglycol is employed as a leveling agent in the formulation of high-gloss and low-VOC (volatile organic compound) coatings.
Ethyl triglycol is used in heat transfer fluids for efficient thermal energy transfer in various industrial processes.
In the printing and packaging industry, it is used in the production of flexographic inks and overprint varnishes.

Ethyl triglycol is added to industrial cleaner formulations for the removal of heavy greases and oils.
Ethyl triglycol is found in the production of decorative and industrial laminates, contributing to their durability and finish.
Ethyl triglycol can serve as an anti-icing and de-icing agent for aircraft surfaces and runways in aviation.

In the wood industry, it is used in the formulation of wood preservatives to protect against fungi and insects.
Ethyl triglycol can be found in industrial lubricants and metalworking fluids, enhancing cutting and grinding operations.
Ethyl triglycol is used in the formulation of corrosion inhibitors for protecting metal surfaces in various applications.
Ethyl triglycol is employed in heat transfer fluids for solar thermal energy systems.
Ethyl triglycol is found in the formulation of optical lens cleaners, aiding in cleaning effectiveness and anti-fog properties.

Ethyl triglycol is utilized in the production of industrial paints and coatings, ensuring consistent and smooth finishes.
Ethyl triglycol is found in the formulation of wood stains and varnishes, enhancing the durability and appearance of wooden surfaces.

Ethyl triglycol is used in the manufacturing of inkjet printer inks for high-quality color printing.
Ethyl triglycol serves as a leveling agent in the production of UV-curable coatings, ensuring an even and glossy finish.

In the semiconductor and electronics industry, it is used as a solvent and co-solvent in chip manufacturing and microelectronics.
Ethyl triglycol is a component in specialty cleaning products for precision instruments and electronics.

Ethyl triglycol can be employed as a wetting agent and dispersant in ceramic and glass manufacturing processes.
Ethyl triglycol is found in adhesion promoters for improved bonding of different materials, such as plastics and metals.
Ethyl triglycol is used in the production of corrosion-resistant coatings for marine and offshore applications.

Ethyl triglycol is found in mold release agents for the easy release of molded objects and components.
Ethyl triglycol serves as a diluent in the formulation of epoxy adhesives and resins.
Ethyl triglycol is utilized in the formulation of rust converters, facilitating the transformation of rust into a stable surface.
Ethyl triglycol can be added to rust inhibitors and rust preventatives to protect against corrosion in various industries.

In the textile industry, it acts as a dye carrier and wetting agent for uniform and efficient dyeing and printing.
Ethyl triglycol is used in the production of anti-fogging agents for eyeglasses, goggles, and protective face shields.
Ethyl triglycol can be found in inkjet printer inks for high-resolution photo printing applications.
In the aviation and aerospace industry, it is used in cleaning and maintenance products for aircraft and spacecraft.

Ethyl triglycol is employed as a coalescing agent in low-VOC (volatile organic compound) architectural coatings, reducing environmental impact.
Ethyl triglycol is added to sealant and adhesive removers to aid in the efficient removal of adhesives and sealants from surfaces.
Ethyl triglycol is used in the plastic molding industry as a processing aid for improved extrusion and molding.
Ethyl triglycol can be found in specialty lubricants for applications in automotive, industrial, and machinery maintenance.

Ethyl triglycol is used in heat transfer fluids for cooling systems in data centers and industrial facilities.
Ethyl triglycol serves as a carrier solvent in the production of insect repellents and personal insect protection products.

Ethyl triglycol is employed in mold inhibitors to prevent mold and mildew growth on surfaces in humid environments.
In the food and beverage industry, Ethyl triglycol can be used as an ingredient in food-grade lubricants and release agents.

Ethyl triglycol is used as a component in adhesive formulations, contributing to the adhesive's bonding strength and flexibility.
Ethyl triglycol can be found in the production of heat-resistant coatings for industrial equipment and surfaces exposed to high temperatures.

In the automotive industry, Ethyl triglycol is utilized in the formulation of anti-freeze and engine coolant solutions.
Ethyl triglycol is added to hydraulic fluids to enhance their lubrication properties and protect hydraulic systems.

Ethyl triglycol is used in the manufacturing of leather and textile dyes, ensuring even and vibrant coloration.
Ethyl triglycol is employed in the production of industrial and institutional disinfectants and sanitizers.
Ethyl triglycol is found in asphalt and bitumen formulations, improving their adhesion and durability in road construction.

In the pharmaceutical industry, it serves as a solvent for the production of oral and topical drug formulations.
Ethyl triglycol can be utilized in the creation of antifungal paints and coatings for buildings and structures.

Ethyl triglycol is added to air fresheners and deodorizers to improve the dispersion of fragrance.
Ethyl triglycol is found in the formulation of industrial-grade hand cleaners and degreasers.

Ethyl triglycol is used in the production of heat-sealing adhesives for packaging and sealing applications.
Ethyl triglycol is employed in the formulation of lubricating oils and greases, enhancing their performance in various machinery.
In the textile industry, it is used in spinning solutions for synthetic fibers, improving their processability.
Ethyl triglycol serves as a component in nail polish removers for efficient removal of nail polish and coatings.
Ethyl triglycol is added to inks used in flexographic printing to improve adhesion and print quality on various substrates.
Ethyl triglycol is utilized in the formulation of herbicides and weed control products for effective and even distribution.

Ethyl triglycol is employed in the production of rubber products to enhance their flexibility and processing.
Ethyl triglycol is used in the formulation of water-based wood adhesives, ensuring strong and durable bonds.

In the production of ceramic glazes and enamels, it serves as a wetting agent to promote even and smooth coverage.
Ethyl triglycol is found in the manufacturing of anti-graffiti coatings to protect surfaces against graffiti and vandalism.

Ethyl triglycol is utilized in the creation of battery electrolytes for improved electrical conductivity.
Ethyl triglycol is added to mold-release agents in the plastic and rubber molding industry for easy demolding.
Ethyl triglycol is used in the formulation of lubricating compounds for precision instruments and machinery.
In the art and craft industry, Ethyl triglycol is employed in the formulation of art paints and inks for its solvency and dispersion properties.



DESCRIPTION


Ethyl triglycol, also known as 2-(2-(2-ethoxyethoxy)ethoxy)ethanol, is a chemical compound with the molecular formula C6H14O4.
Ethyl triglycol is an ethylene glycol ether and is part of the glycol ether family.
Ethyl triglycol is commonly used as a solvent and coalescing agent in various industrial and commercial applications, including coatings, paints, and cleaning products.

Ethyl triglycol is known for its ability to dissolve a wide range of substances and its contribution to the stability and performance of various formulations.
Ethyl triglycol is a clear, colorless liquid with a mild, ether-like odor.
Ethyl triglycol should be handled and stored following appropriate safety and handling guidelines.

Ethyl triglycol is a clear and colorless liquid chemical compound.
Ethyl triglycol has a mild, ether-like odor.

Ethyl triglycol is part of the glycol ether family, known for its versatility as a solvent.
Ethyl triglycol is composed of carbon, hydrogen, and oxygen atoms.
Ethyl triglycol's chemical formula is C6H14O4.

Ethyl triglycol is often used as a coalescing agent in various applications.
Ethyl triglycol is known for its excellent solvency, capable of dissolving a wide range of polar and nonpolar substances.
Ethyl triglycol plays a crucial role in the formulation of paints and coatings, enhancing film formation.

Ethyl triglycol is a common ingredient in water-based paints, where it aids in improving adhesion and durability.
Ethyl triglycol is used in the production of industrial and architectural coatings, such as latex paints.
Ethyl triglycol contributes to the stability and performance of coatings, ensuring even and smooth surfaces.
Ethyl triglycol is valued for its ability to reduce the drying time of paints and coatings.

In the chemical industry, it serves as a versatile solvent for various chemical reactions and formulations.
Ethyl triglycol is employed in the formulation of cleaning products, including industrial and household cleaners.

Ethyl triglycol aids in the removal of grease, oils, and stains in cleaning solutions.
Ethyl triglycol is used as a carrier solvent in the production of inkjet printer inks, improving print quality.

Ethyl triglycol is a key ingredient in the cosmetics industry, found in makeup removers and facial cleansers.
Ethyl triglycol is used as a wetting and leveling agent in the production of inks and coatings.
Ethyl triglycol helps prevent defects such as craters and pinholes in coatings.

Ethyl triglycol is employed as a coalescing agent in adhesives and sealants to enhance their performance.
Ethyl triglycol is compatible with a wide range of materials, making it suitable for various formulations.
Ethyl triglycol is known for its slow evaporation rate, making it suitable for applications requiring extended working times.

Ethyl triglycol is generally stable under normal conditions and poses minimal reactivity risks.
Ethyl triglycol should be handled and stored according to safety guidelines and with appropriate personal protective equipment.



PROPERTIES


Chemical Formula: C6H14O4
Molecular Weight: 166.18 g/mol
Physical State: Clear and colorless liquid
Odor: Mild, ether-like odor
Melting Point: Approximately -77.6°C (-107.7°F)
Boiling Point: Approximately 165-166°C (329-331°F)
Density: Approximately 1.1 g/cm³ at 20°C (68°F)
Solubility:
Highly soluble in water.
Soluble in a wide range of organic solvents, including alcohols, ketones, and ethers.
Vapor Pressure: Negligible at room temperature.
Viscosity: Low to moderate viscosity.
Flash Point: Approximately 83°C (181.4°F) closed cup
Autoignition Temperature: Approximately 290°C (554°F)
Refractive Index: Approximately 1.424 at 20°C (68°F)
Surface Tension: Approximately 35 dyn/cm at 20°C (68°F)
pH: Approximately neutral (pH 7)
Heat of Combustion: Approximately 26.7 MJ/kg
Heat of Vaporization: Approximately 291 J/g
Dielectric Constant: Approximately 17 at 20°C (68°F)
Specific Heat: Approximately 2.12 J/g·°C
Evaporation Rate: Slow



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
Administer artificial respiration if the person is not breathing and if qualified to do so.


Skin Contact:

In case of skin contact, remove contaminated clothing and shoes.
Wash the affected skin with plenty of soap and water for at least 15 minutes.
Seek medical attention if skin irritation, redness, or other symptoms develop.


Eye Contact:

If the chemical comes into contact with the eyes, immediately rinse the affected eye(s) with gently flowing water for at least 15 minutes, keeping the eyelids open to ensure thorough rinsing.
Seek immediate medical attention.
Do not use eye drops or other eye medications without medical advice.


Ingestion:

If swallowed, do not induce vomiting.
Rinse the mouth thoroughly with water if the person is conscious.
Seek immediate medical attention.
Do not give anything by mouth to an unconscious person.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
When handling Ethyl triglycol, wear appropriate PPE, including chemical-resistant gloves, safety goggles or face shield, lab coat or protective clothing, and respiratory protection if necessary.

Ventilation:
Work with Ethyl triglycol in well-ventilated areas or use local exhaust ventilation to prevent the buildup of vapor concentrations.
Ensure that the ventilation system effectively removes airborne contaminants.

Avoidance of Contact:
Avoid skin and eye contact.
In case of contact, follow first aid measures promptly.

No Eating or Drinking:
Do not eat, drink, or smoke while handling the chemical.
Wash hands thoroughly before eating, drinking, or using the restroom.

Prevent Inhalation:
Avoid breathing vapors or mist. Use respiratory protection as required based on exposure levels.

Prevent Spills:
Take precautions to prevent spills.
Use appropriate spill control measures, including absorbent materials, to clean up and contain spills promptly.

Storage:
Store Ethyl triglycol in a cool, dry, and well-ventilated area away from incompatible materials.
Keep containers tightly closed when not in use.

Labeling:
Ensure containers are clearly labeled with the name of the chemical, hazard warnings, and appropriate safety information.

Separation:
Store away from strong oxidizing agents, acids, and bases to avoid potential chemical reactions.

Electrical Equipment:
Use explosion-proof electrical equipment in areas where Ethyl triglycol is handled.

Handling Containers:
When transferring the chemical from one container to another, use approved containers and equipment to prevent leaks or spills.


Storage:

Temperature:
Store Ethyl triglycol at temperatures between 0°C (32°F) and 30°C (86°F) to maintain stability and prolong shelf life.

Ventilation:
Ensure storage areas are well-ventilated to disperse any potential vapors.

Container Material:
Use containers made of compatible materials such such as stainless steel, carbon steel, or polyethylene.

Avoid Sunlight:
Store containers away from direct sunlight and other heat sources to prevent temperature fluctuations.

Separation:
Keep Ethyl triglycol containers separated from food and beverage storage areas and away from children and unauthorized personnel.

Security:
Store in a secure location to prevent unauthorized access or tampering.

Fire Prevention:
Keep containers away from potential ignition sources or open flames.

Leak Control:
Maintain spill control and containment measures to prevent leakage and environmental contamination.

Emergency Equipment:
Ensure that safety showers and eye wash stations are readily available in the storage area.

Compatibility:
Store away from incompatible materials and hazardous chemicals.
Refer to the manufacturer's guidelines and safety data sheet (SDS) for specific storage instructions.



SYNONYMS


2-(2-(2-Ethoxyethoxy)ethoxy)ethanol
Triethylene glycol monoethyl ether
Ethyltriglycol
Ethyl Tri Glycol
Ethoxytriglycol
2,2,2-Nitrilotriethanol, monoethyl ether
Triethylene glycol ethyl ether
Triethylene glycol ethyl monoether
2-(2-Ethoxyethoxy)ethanol
Triglycol ethyl ether
Ethyl ether triethylene glycol
Ethyl Glycol Triethylene Ether
Ethyl Triethylene Glycol Ether
Ethyl Triethylene Glycol Monoether
3,6,9-Trioxatetradecon-1-ol, 3,6,9-triethyl ether
2,2,2-Nitrilotriethanol monoethyl ether
Nitrilotriethanol monoethyl ether
TEGEE (an acronym derived from TriEthylene Glycol Ethyl Ether)
Ethyl triethylene glycol
Ethyl tritetraethylene glycol
2-(2-(2-Ethoxyethoxy)ethoxy)ethanol
Ethyl trioxaundecane-1,11-diol
Ethyl ether triethylene glycol
2-(2-Ethoxyethoxy)ethanol
3,6,9-Trioxatetradecon-1-ol
Triglycol ethyl ether
2-Ethoxyethyl ether of triethylene glycol
Ethyl glycol triethylene ether
2,2',2''-Nitrilotriethanol monoethyl ether
Ethyl triethylene glycol monomethyl ether
Triethylene glycol ethyl monoether
Ethyltriglycol
Ethyl Tri Glycol
Ethoxytriglycol
2,2,2-Nitrilotriethanol monoethyl ether
Ethyl glycol ether of triethylene glycol
Ethyl glycol ether of triglycol
Triethylene glycol ethyl ester
Ethyl triethylene glycol ether
2,2,2-Nitrilotriethanol monoethyl ester
Ethyl Trisiloxane
Synonyms: 3- ethyl heptamethyl trisiloxane ethyl-methyl-bis(trimethylsilyloxy)silane 3- ethylheptamethyltrisiloxane trisiloxane, 3-ethyl-1,1,1,3,5,5,5-heptamethyl- CAS Number 17861-60-8
ETHYL VANILLIN
ETHYLCELLULOSE, N° CAS : 9004-57-3 - Éthylcellulose. Nom INCI : ETHYLCELLULOSE. Additif alimentaire : E462. Ses fonctions (INCI). Agent fixant : Permet la cohésion de différents ingrédients cosmétiques. Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles. Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques
Ethyl vanillin fema 2464
3-Ethoxy-4-hydroxybenzaldehyde; Ethylvanillin; Bourbonal CAS NO : 121-32-4
Éthylcellulose
ETHYLENE DIAMINE; 1,2-Ethylenediamine; 1,2-Diaminoethane; EDA; Ethane-1,2-diamine; Aethaldiamin (German); Aethylenediamin (German); 1,2-diaminoaethan (German) ; 1,2-Diamino-ethaan (Dutch); 1, 2-Diamino-Ethano cas no: 107-15-3
Ethylendiamine Tetra(methylenephosphonic Acid) Pentasodium Salt
cas no: 141-78-6 Acetic acid, ethyl ester; Ethyl acetic ester; Acetidin; Acetate d'ethyle (French); Acetato de etilo (Spanish); ; Acetic ester; Acetoxyethane; Aethylacetat (German); Essigester (German); Ethyl ethanoate; hylacetaat; (Dutch); Ethyle (acetate d') (French); hylester kyseliny octove; (Czech); Etile (Acetato Di) (Italian); tan etylu (Polish);
ETHYLENE BIS(STEARAMIDE)
ETHYLENE BIS(STEARAMIDE) = EBS = LICOWAX C = N,N′-ETHYLENEDI(STEARAMIDE)


CAS Number: 110-30-5
EC Number: 203-755-6
MDL number: MFCD00059224
Molecular Formula: C38H76N2O2 / [CH3(CH2)16CONHCH2-]2


Ethylene bis(stearamide) is an organic compound with the formula (CH2NHC(O)C17H35)2.
Ethylene bis(stearamide) is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.
Ethylene bis(stearamide) is derived from the reaction of ethylenediamine and stearic acid.
Ethylene bis(stearamide) is a white solid of low toxicity that provides a slippery coating for a variety of applications.


Ethylene bis(stearamide) is a synthetic wax with high melting point.
Ethylene bis(stearamide) is a hard and brittle white high melting point wax.
Ethylene bis(stearamide)'s industrial products are slightly yellow particles or white powder, non-toxic, and have no side effects on the human body.


Ethylene bis(stearamide) is an organic compound with the formula (CH2NHC(O)C17H35)2.
Ethylene bis(stearamide) is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.
Ethylene bis(stearamide) is derived from the reaction of ethylenediamine and stearic acid.
Ethylene bis(stearamide) is a white solid of low toxicity that provides a slippery coating for a variety of applications.


Ethylene bis(stearamide) is a synthetic wax that has fatty amide groups that can interact with the surface of a variety of nanoparticles.
Synthhetic wax having high melting point, Ethylene bis(stearamide) has some functions as internal and external lubricant, releasing and dispersion agent of pigment for the most thermosetting and thermoplastic resins.
Ethylene bis(stearamide) is derived from stearic acid and ethylenediamine.


Ethylene bis(stearamide) is white or slight yellow powder or granule
Ethylene bis(stearamide) is an organic compound with the formula (CH2NHC(O)C17H35)2.
Ethylene bis(stearamide) is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.
Ethylene bis(stearamide) is derived from the reaction of ethylenediamine and stearic acid.


Ethylene bis(stearamide) is an amide wax.
Ethylene bis(stearamide) by MLA Group has low acid value ( free fatty acid ), high melting point, and excellent white colour, and high purity.
Ethylene bis(stearamide) is white spherical particle, non-toxic and no side effect on humans.
Ethylene bis(stearamide) is insoluble in most organic solvents at room temperature.


Ethylene bis(stearamide) is stable to acid, alkali and water medium.
Ethylene bis(stearamide) is soluble in hot chlorinated hydrocarbons and aromatic hydrocarbon solvents.
Wettability is available for water above 80°C
Substitute Malay and Indonesian products, partly substitute kao ES-FF products, low acid value, low amine value, high performance, high purity, excellent heat resistance and stability.


Ethylene bis(stearamide) acts as a slip and anti-block additive.
Ethylene bis(stearamide) is based on a non-vegetable origin, secondary bis-amide.
Ethylene bis(stearamide) offers mold release benefits in polyamides (nylon).
Ethylene bis(stearamide) disperses evenly through the polymer in the melt phase, and migrates to the surface where it forms a thin lubricating layer that reduces coefficient of friction between surfaces and reduces unwanted adhesion.


Ethylene bis(stearamide) also functions as an external lubricant for PVC and a process aid for polyolefins.
Ethylene bis(stearamide) is suitable for composites, styrenics and rubber.
The recommended dosage levels are 500-2000 ppm in films and 0.2-1.0% in molding applications.
Ethylene bis(stearamide) is EU 10/2011, FDA (175.105) and FDA (175.300) approved.


Ethylene bis(stearamide) has a shelf life of 365 days.
Ethylene bis(stearamide) is also available in bead form.
Ethylene bis(stearamide) is ethylene-bis-stearamide of non-vegetable origin.
Ethylene bis(stearamide) is a secondary bis amide effective as an anti-block agent and process aid for polyolefins.


Ethylene bis(stearamide) is a secondary bis-amide additive.
Ethylene bis(stearamide) has good anti-blocking properties in polyolefins.
Ethylene bis(stearamide) is an amide wax of type N,N-bis-stearyl ethylenediamine with particularly good thermostability.
Ethylene bis(stearamide) is an amide wax of type N,N-bis-stearyl-ethylenediamine.


Ethylene bis(stearamide) is compatible with styrene & styrenic copolymer, PVC, PO and PS.
Ethylene bis(stearamide) exhibits good thermostability and excellent slip properties.
Ethylene bis(stearamide) powder is an amide wax of type N,N-bis-stearyl ethylenediamine with particularly good thermostability.
Ethylene bis(stearamide) has no influence on the transparency of the Polymers.


Ethylene bis(stearamide) is an organic compound with the formula (CH2NHC(O)C17H35)2.
Ethylene bis(stearamide) is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.
Ethylene bis(stearamide) is derived from the reaction of ethylenediamine and stearic acid.


Ethylene bis(stearamide) is a white solid that provides a slippery coating for a variety of applications.
Ethylene bis(stearamide) is a hard and brittle white high melting point wax, it's industrial products are slightly yellow fine particles, insoluble in most solvents at room temperature, stable to acids and bases, and aqueous media, soluble in hot chlorinated hydrocarbons and aromatic hydrocarbons solvents, it’s powder slippery feeling strong, above 80 ℃ to water with wettability of the compound.



USES and APPLICATIONS of ETHYLENE BIS(STEARAMIDE):
Ethylene bis(stearamide) is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.
Ethylene bis(stearamide) is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.


Ethylene bis(stearamide) is used in powder metallurgy.
Ethylene bis(stearamide), a new plastic lubricant developed in recent years, is widely used in the molding and processing of PVC products, ABS, high impact polystyrene, polyolefin, rubber and plastic products.
Ethylene bis(stearamide) is compared with traditional lubricants such as paraffin wax, polyethylene wax, stearate, etc.


Ethylene bis(stearamide) not only has good external lubrication effect, but also has good internal lubrication effect, which improves the fluidity and demoulding property of melted plastic in plastic molding process, thus improving the yield of plastic processing, reducing energy consumption, and making the product obtain high surface smoothness and smoothness.
Cosmetic Uses of Ethylene bis(stearamide): viscosity controlling agents


Ethylene bis(stearamide) is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.
Because of it's excellent lubricating properties, Ethylene bis(stearamide) is widely used internally and/or externally in most plastics such as ABS, PS, PP, etc.


Ethylene bis(stearamide) is used as additive Ethylenebisstearamide can be incorporated directly into polymers to prevent any unwanted adhesion.
Ethylene bis(stearamide) is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.
Ethylene bis(stearamide) can also be used as a process aid, for example to improve dispersion of fillers.


Ethylene bis(stearamide) can also be a binder in the precise engineering metal part.
Due to it's good dispersing ability and surface migration Ethylene bis(stearamide) can be used in printing inks.
A field of application is the bitumen industry: When used in asphalt binder for road making (asphalt modifiers), Ethylene bis(stearamide) increases its softening point and enhances its visco-elasticity.


Ethylene bis(stearamide) is used as Release agent and flow promoter for all engineering resins, Styrenics and their copolymers
Ethylene bis(stearamide) is used Lubricant in powder metal molding, rubber, adhesives, coatings, wire drawing, wood plastic composite, Defoamer in paper, Lubricant for Polyacetals, Water repellent for paper, Intermediate for defoamers, and Delustering agent for furniture finishes and printing inks


Ethylene bis(stearamide) is used Dispersing agent for masterbatch applications, preferably for engineering resins and PVC, and Modifier in textile auxiliaries
Ethylene bis(stearamide) is used as lubricant with good inner or outer lubricant action and has good coordination when used together with other lubricants as high grade alcohols, aliphatic acid esters, calcium stearate and paraffin.


In the processing of ABS, AS, hard PVC, polyformaldehyde, polycarbonate, polyurethane and phenolformaldehyde resins, Ethylene bis(stearamide) is used as lubricant demoulding agent with a quantity of 0.5~1.5 %.
Ethylene bis(stearamide) is used as anti-adhesive agent for various polymer film or sheets.
An addition of 0.5-1 % of Ethylene bis(stearamide) can not only prevent the occurrence of air bubbles but also make the plastic bags be slippery so as to be opened easily.


Ethylene bis(stearamide) can remarkably enhance the heat-resistant and weather-resistant properties while coordinating with chief stabilizer in formulation of inorganic filler for PVC and polyolefin.
As Ethylene bis(stearamide) has strong cohesions with pigment or other filler, Ethylene bis(stearamide) can improve the dispersion and coupling property of fillers in the polymers to enhance the commercial value of the products.


Ethylene bis(stearamide) is used as nucleation transparency agent to reduce the nucleating time in compounds such as polyolefins, polyformaldehyde and polyamide, promote the structure of resin to become fine, thus improve the mechanical property and transparency of the products.
In synthetic fiber industry, Ethylene bis(stearamide) can improve the heat-resistant, weather-resistant property of polyester and polyamide and bring about certain antistatic effects.


Ethylene bis(stearamide) is used in the spinning of antistatic nylon fiber as additive and also is able to reduce the breaking of yarn.
Ethylene bis(stearamide) is used as processing auxiliary of rubber. Besides the lubricant demoulding property and modifying performance of filler surface, Ethylene bis(stearamide) can raise the surface fineness of rubber pipes and rubber plates to act as rubber surface polishing agent.


Ethylene bis(stearamide) improves the kneading, processing and vulcanization performance of rubber grains in the processing of rubber.
Ethylene bis(stearamide) is added in the coating production to increase the uniform dispersion of pigment and filler, improve the surface leveling property of baking paint, prevent the stripping off of paint film and improve water-proof and acid-resistant and alkali-resistant property.


In nitrocellulose lacquers, Ethylene bis(stearamide) can bring about the flatting action.
Ethylene bis(stearamide) is used as lubricant in powder metallurgy (PM) steels to reduce the inter-particle and die-wall friction during pressing and hence improve powder compressibility and ejection of the component from the compaction tool.
Ethylene bis(stearamide) can help to increase the melting point of petroleum products; lubricant and corrosive agent of metal wire drawing.


Ethylene bis(stearamide) can help to increase the smoothness and fineness for insulator layer of electric power and cable.
Ethylene bis(stearamide) can decrease the viscosity of asphalt and improve it’s softening point and weathering resistance when added to asphalt.
Ethylene bis(stearamide) derived from stearic acid with ethylene diamine is a synthetic was used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability.


Ethylene bis(stearamide) is also used as a release agents, antistats, and antifoaming agent.
Ethylene bis(stearamide) is used as defoamer/ anti-foaming agent and coating component of paper for paper-making industry.
Added in the manufacturing process of dope and oil paint to enhance salt mist and dampproof effect and to improve performance of paint remover.
As Ethylene bis(stearamide) has good wearable performance and smoothing performance, fits for improving polishing performance of lacquer, air release of surface with holes, Ethylene bis(stearamide) is also well used as dulling agent for polishing furniture and printing ink.


Ethylene bis(stearamide) is used for lubricant of plastic and metal molding, adhesion preventives, viscosity modifier, anti-corrosion of wax, water resistance of coating and spray paint.
Ethylene bis(stearamide) is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits.
Ethylene bis(stearamide) is also used as release agents, antistatic agents, and antifoaming agents.


Ethylene bis(stearamide) can be used for a wide range of applications such as lubricants, activators and dispersing agents that reduce the friction in the system and increase the rate of processing.
Ethylene bis(stearamide) is used Raw materials, Ethylenediamine Trap Stearic acid, Preparation Products, defoaming agent OTD


Ethylene bis(stearamide) is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.
Ethylene bis(stearamide) is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.


Ethylene bis(stearamide) is used in powder metallurgy.
Ethylene bis(stearamide) is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.
Because of its excellent lubricating properties Ethylene bis(stearamide) is widely used internally and/or externally in most plastics such as ABS, PS, PP etc.


Ethylene bis(stearamide) is used as additive Ethylene bis(stearamide) can be incorporated directly into polymers to prevent any unwanted adhesion.
Adhesive pellets or film often develop adhesion between the polymer pellets or layers when exposed to elevated temperatures and pressures.
Ethylene bis(stearamide) can be found in industrial use: in processing aids at industrial sites, formulation in materials and as processing aid.


Ethylene bis(stearamide) can be found in: outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).
Ethylene bis(stearamide) can be found in products with material based on: rubber (e.g. tyres, shoes, toys) and fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys).


Ethylene bis(stearamide) is used in the following products: washing & cleaning products, lubricants and greases, coating products, inks and toners and polishes and waxes.
Ethylene bis(stearamide) is used in the following areas: formulation of mixtures and/or re-packaging.
Ethylene bis(stearamide) is used for the manufacture of: rubber products and plastic products.


Ethylene bis(stearamide) can be found in: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Ethylene bis(stearamide) is used in the following products: polymers, lubricants and greases, metal working fluids, pharmaceuticals and cosmetics and personal care products.


Ethylene bis(stearamide) can be found in industrial use: formulation of mixtures, formulation in materials, as processing aid, manufacturing of the substance and in processing aids at industrial sites.
Ethylene bis(stearamide) is used in the following products: lubricants and greases, polymers, washing & cleaning products, inks and toners, metal working fluids, textile treatment products and dyes and coating products.


Ethylene bis(stearamide) is used in the following areas: formulation of mixtures and/or re-packaging and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Ethylene bis(stearamide) is used for the manufacture of: rubber products, textile, leather or fur, machinery and vehicles and chemicals.
Ethylene bis(stearamide) can be found in industrial use: in processing aids at industrial sites, as processing aid, in the production of articles, formulation in materials, formulation of mixtures and of substances in closed systems with minimal release.


Ethylene bis(stearamide) can be found in: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).
Ethylene bis(stearamide) is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.


Ethylene bis(stearamide) can also be used as a process aid, for example to improve dispersion of fillers.
Ethylene bis(stearamide) is a bis-amide polymer additive that lowers the temperature at which the asphalt softens.
Ethylene bis(stearamide) is used as processing aid for resins and polymers and as defoaming agent.
Ethylene bis(stearamide) is traditionally used as lubricant and binder for cold compaction of powdered metal parts.


Ethylene bis(stearamide) is a bis-amide polymer additive that lowers the temperature at which the asphalt softens.
Ethylene bis(stearamide) is used as processing aid for resins and polymers and as defoaming agent.
Ethylene bis(stearamide) is traditionally used as lubricant and binder for cold compaction of powdered metal parts.
Ethylene bis(stearamide) is used as a processing aid for resins and polymers and as a defoaming agent.


Ethylene bis(stearamide) is an effective lubricant, processing aid, slip additive and pigment dispersant aid for most polymers.
Ethylene bis(stearamide) is an ethylenebisstearamide, specifically developed to afford low, consistent viscosities and superior cost performance in paper pulp defoamer applications.
Useful as defoamer for paper making and textile processing .


Ethylene bis(stearamide) is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Ethylene bis(stearamide) is used in the following products: adhesives and sealants, lubricants and greases, coating products, polishes and waxes and washing & cleaning products.


Ethylene bis(stearamide) is added to oil based defoamers to improve foam knock down.
Ethylene bis(stearamide) can also be used as a process aid, for example to improve dispersion of fillers.
Ethylene bis(stearamide) has proven mould release action in polyamides, and is a lubricant for PVC.
Ethylene bis(stearamide) is a bis-amide anti-blocking additive used to prevent blocking and as anti-tack of adhesives.


Ethylene bis(stearamide) is used to prevent the adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.
Ethylene bis(stearamide) has proven mold release benefits in nylon and is a lubricant for PVC.
Ethylene bis(stearamide) is an internal additive and can be incorporated into resin as supplied or via masterbatch / pre-blend.


Experience has shown that simple manual mixing prior to processing will normally give an acceptable dispersion though, mechanical means are preferred.
Typical addition levels vary depending on polymer and lubrication required.
Ethylene bis(stearamide) acts as a slip and anti-block agent, mold release agent and lubricant for PVC.


Ethylene bis(stearamide) is non-toxic and can be dispersed evenly through the polymer in the melt phase.
Ethylene bis(stearamide) migrates to the surface of the polymer where it forms a thin lubricating layer.
Ethylene bis(stearamide) is used in the following products: adhesives and sealants, lubricants and greases, coating products, polishes and waxes and washing & cleaning products.


Ethylene bis(stearamide) is used in the following products: washing & cleaning products, lubricants and greases, coating products, inks and toners and polishes and waxes.
Ethylene bis(stearamide) is used in the following areas: formulation of mixtures and/or re-packaging.
Ethylene bis(stearamide) is used for the manufacture of: rubber products and plastic products.


Ethylene bis(stearamide) is used in the following products: polymers, lubricants and greases, metal working fluids, pharmaceuticals and cosmetics and personal care products.
Ethylene bis(stearamide) is used for the manufacture of: rubber products, textile, leather or fur, machinery and vehicles and chemicals.


Ethylene bis(stearamide) is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.
Ethylene bis(stearamide) is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.


Ethylene bis(stearamide) is used in powder metallurgy.
Lubrication performance is excellent, anti-calcium salt ability is strong, drag reduction effect is good, used for drilling in saturated brine to reduce power consumption.
Ethylene bis(stearamide) is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.


Because of it's excellent lubricating properties, Ethylene bis(stearamide) is widely used internally and/or externally in most plastics such as ABS, PS, PP etc.
Ethylene bis(stearamide) is used as additive EBS can be incorporated directly into polymers to prevent any unwanted adhesion.
Adhesive pellets or film often develop adhesion between the polymer pellets or layers when exposed to elevated temperatures and pressures.


Ethylene bis(stearamide) is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.
Ethylene bis(stearamide) can also be used as a process aid, for example to improve dispersion of fillers.
Ethylene bis(stearamide) is used as an additive for hot melt adhesives.


Slip- and anti-blocking agent for polyolefins and PVC, especially for film applications and also lubricant for wood plastic composites and plastics.
Dispersing agent for masterbatch applications, preferably for engineering resins and PVC.
Ethylene bis(stearamide) provides typical slip and anti blocking characteristics to all polymers e.g. in films.


Ethylene bis(stearamide) is useed Anti-Blocking Agent, Release Agent, Slip Agent, Flow Promoter, and Hot-Melt Adhesive
Ethylene bis(stearamide) improves flow and has no influence on transparency of polymers.
Ethylene bis(stearamide) acts as a lubricant, release & antiblocking agent for all engineering resins and dispersing agent for masterbatch applications.


Ethylene bis(stearamide) provides typical slip and anti blocking characteristics to all polymers.
Ethylene bis(stearamide) powder does not affect the transparency of polymers and acts as lubricant in a wide variety of polymers like PVC, PO, PS and engineering plastics.


-Applications of Ethylene bis(stearamide):
*Adhesives & sealants
*Composites
*Inks


-Application of Ethylene bis(stearamide):
Water treatment
-Mode of action:
Ethylene bis(stearamide) can be dispersed evenly through the polymer in the melt phase.
Ethylene bis(stearamide) migrates to the surface of the polymer where it forms a thin lubricating layer.
This layer reduces the coefficient of friction between surfaces and prevents any unwanted adhesion.


-Ethylene bis(stearamide) is used as an internal and external slip agent in many thermoplastic and thermosetting plastics, the most representative ones are ABS, PS, ABS, PVC, also used in PE, PP, PVAC, cellulose, Accurate, Nylon, phenolic-Resin, amino plastics.
-Ethylene bis(stearamide)has a good finish and good film release.


-As a lubricant of polyformaldehyde, the addition amount is 0.5%, which improves the melt flow rate and the film release, and the whiteness, thermal stability and physical index of polyformaldehyde all reach the superior index.
-Chemical fiber:
Ethylene bis(stearamide) can improve the heat and weather resistance, fluidity of polyester, polyamide fiber, and give a certain anti-static effect.


-Rubber:
Synthetic resins and rubber such as Vinyl, polychloroprene, GRS (SBR) add 1~3% EBS to their emulsions, it has a good anti-viscosity and anti-caking effect, EBS is used in floor mats for automobiles, drainage pipes, and other rubber products to increase the effect of surface gloss.


-Release agent:
Phenolic resin for sand casting with Ethylene bis(stearamide) can be used as a release agent.
-Powder Coating:
Ethylene bis(stearamide) can be used as flow additives for powder coatings.


-Pigment, filler dispersant:
*Ethylene bis(stearamide) is used as a pigment dispersant for plastic.
*Pigment dispersant for chemical fiber masterbatches, such as ABS, PS, polypropylene, polyester masterbatches.
*Ethylene bis(stearamide) can also be used as diffusion powder for plastic color matching.
*Depending on the amount of pigment and filler added, the addition amount is 0.5~5%.


-Paint, Ink:
*Adding 0.5~2% Ethylene bis(stearamide) can improve the effect of salt spray and moisture resistance in the manufacture of paint and lacquer.
*Adding Ethylene bis(stearamide) in the paint can improve the performance of the paint stripper and can improve the leveling of the baked enamel surface.
*Ethylene bis(stearamide) can be used as a matting agent in furniture polishing agents and printing ink.
*After micronization (particle size: d50 about 6μ, d 90 about 12μ), Ethylene bis(stearamide) has excellent anti-abrasion and smoothness and can be used in lacquer systems to improve polishability and degassing on a porous surface.


-Other uses of Ethylene bis(stearamide):
*Melting point rising agent for petroleum products
*Lubricant and anti-corrosion agent for metal drawing
*Potting material for electrical components; defoaming agent and paper coating ingredient for paper industry
*Ethylene bis(stearamide) is used as a defoaming agent and permanent water pulling agent for dyeing works in textile dyeing and finishing
*Adding this product in asphalt can reduce the viscosity of asphalt and improve the softening point, water-resistance and weather resistance of asphalt.


-Hot-Melt Adhesive Applications of Ethylene bis(stearamide):
*Release agent and flow promoter for all engineering resins, Styrenics and their copolymers.


-Consumer Goods:
*Appliances & Electronics
*Adhesives & Sealants: Industrial & *Assembly Adhesives
*Electronics Adhesives
*Industrial Manufacturing
*Healthcare & Pharma — Medical
*Medical Tapes & Adhesives
*Electrical & Electronics — Packaging & Assembly
*Adhesives & Sealants
*Adhesive & Sealant Type


-Plastic uses of Ethylene bis(stearamide):
Lubricants inside or outside many plastics such as ABS, PS, AS, PVC, PE, PP, PVAC, cellulose acetate, nylon, phenolic resin and amino plastics.
Ethylene bis(stearamide) has a good surface quality and demoulding performance.


-Rubber:
Synthetic resin and rubber will have good anti-adhesive and anti-caking effect by adding Ethylene bis(stearamide) in their emulsion.
Ethylene bis(stearamide) has a good effect to the increase surface gloss when added to rubber products.


-Chemical fiber:
Ethylene bis(stearamide) can improve heat and weather resistance performance of polyester and polyamide fiber, and has some anti-static effect.


-Pigment and filler:
Ethylene bis(stearamide) can be used as pigment dispersant of plastic , fiber, such as ABS, PS, polypropylene fibre and PET fiber and other color masterbatch.


-Coatings and printing ink:
When manufacturing coating and painting, Ethylene bis(stearamide) can improve the effect of salt spray and moistureproof by adding Ethylene bis(stearamide).
Ethylene bis(stearamide) can help to improve the paint stripper performance of paint when added, and to increase the leveling performance of baking enamel varnish.



BENEFITS of ETHYLENE BIS(STEARAMIDE):
-Excellent slip and anti-blocking properties when used in PVC, engeneering resins, PO film and compounds
-Good release properties in PVC and thermoplastics
-Improves flow of polymers
-No influence on transparency of polymers
-Wide food approval



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENE BIS(STEARAMIDE):
Appearance: White, waxy crystals
Odor: Odourless
Melting point: 144 to 146 °C (291 to 295 °F; 417 to 419 K)
Flash point: 280 °C (536 °F; 553 K)
Physical state: Beads
Color: white
Odor: odorless
Melting point/range: 144 - 146 °C - lit.
Initial boiling point and boiling range: 260 °C at 1.013 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: ca.270 °C - DIN 51758
Autoignition temperature: ca.380 °C at 1.013 hPa - DIN 51794
Decomposition temperature: > 200 °C -
pH: No data available
Viscosity Viscosity, kinematic: No data available
Viscosity, dynamic: ca.10 mPa.s at 150 °C
Water solubility at 20 °C: insoluble

Partition coefficient: n-octanol/water log Pow: 13,98 at 25 °C
Vapor pressure: Not applicable
Density: 1 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 720.34 °C. @ 760.00 mm Hg (est)
Flash Point: 213.00 °F. TCC ( 100.70 °C. ) (est)
logP (o/w): 14.787 (est)
Soluble in: water, 2.049e-010 mg/L @ 25 °C (est)

Molecular Weight: 593.0
XLogP3-AA: 15.7
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 35
Exact Mass: 592.59067967
Monoisotopic Mass: 592.59067967
Topological Polar Surface Area: 58.2 Ų
Heavy Atom Count: 42
Formal Charge: 0
Complexity: 503
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Melting point: 144-146 °C(lit.)
Boiling point: 646.41°C (rough estimate)
Density: 1 g/cm3 (20℃)
vapor pressure: 0.000023 Pa (20 °C)
refractive index: 1.4670 (estimate)
Flash point: 280℃
storage temp.: 2-8°C
solubility: ketones, alcohols and aromatic solvents at their boiling points: soluble
pka: 15.53±0.46(Predicted)
form: beads
Appearance: Powdery
Smell: No smell
Color (Gardner): ≤3#
Melting Point (℃): 141.5-146.5
Acid Value (mgKOH/g): ≤7.50
Amine value (mgKOH/g): ≤2.50
Moisture (wt%): ≤0.30
Mechanical impurity: Φ0.1-0.2mm(individual/10g)



FIRST AID MEASURES of ETHYLENE BIS(STEARAMIDE):
-Description of first-aid measures:
*After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*After swallowing:
Make victim drink water (two glasses at most).
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ETHYLENE BIS(STEARAMIDE):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of ETHYLENE BIS(STEARAMIDE):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENE BIS(STEARAMIDE):
-Control parameters
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ETHYLENE BIS(STEARAMIDE):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of ETHYLENE BIS(STEARAMIDE):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



SYNONYMS:
N,N-ethylenedi(stearamide)
1,2-distearamidoethane
N,N-Ethylenebisoctadecanamide
N,N'-ethylene bis-stearamide
N,N'-ethane-1,2-diyldioctadecanamide
2,5-dihexadecylhexanediamide
1,2-Bis(stearoylamino) ethane
N,N′-1,2-Ethanediylbisoctadecanamide
N,N′-Ethylenedi(stearamide)
Ethylene distearylamide
N,N′-(Ethane-1,2-diyl)di(octadecanamide)
ETHYLENE-BIS-STEARAMIDE
waxc
EBSA
advawax
acrawaxc
acrowaxc
lubrolea
5-AC-13C4
acrawaxct
110-30-5
N,N'-Ethylenebis(stearamide)
Plastflow
Ethylene distearamide
N,N'-(Ethane-1,2-diyl)distearamide
Advawax
Acrowax C
Acrawax CT
Lubrol EA
Ethylenedistearamide
Microtomic 280
Advawachs 280
Ethylenebis(stearylamide)
Abril wax 10DS
Carlisle 280
Nopcowax 22-DS
Ethylenebisstearoamide
Advawax 275
Advawax 280
Carlisle Wax 280
Armowax ebs-P
Ethylenebis(stearamide)
Octadecanamide, N,N'-1,2-ethanediylbis-
N,N'-Ethylenebisoctadecanamide
1,2-Bis(octadecanamido)ethane
Chemetron 100
N,N'-ETHYLENE DISTEARYLAMIDE
N,N'-Ethylenedistearamide
Ethylenediamine steardiamide
Ethylenediamine bisstearamide
N,N'-Distearoylethylenediamine
Ethylenebisstearamide
N,N'-Ethylenebisstearamide
NN'-Ethylenebis(stearamide)
Stearic acid, ethylenediamine diamide
Ethylenebisoctadecanamide
Octadecanamide, N,N'-ethylenebis-
UNII-603RP8TB9A
N-[2-(octadecanoylamino)ethyl]octadecanamide
N,N-Ethylenebis(stearamide)
603RP8TB9A
N,N'-ethane-1,2-diyldioctadecanamide
Acrawax C
Kemamide W 40
N,N'-Ethylenedi(stearamide)
WAX C
N,N-Ethylenebisstearamide
CCRIS 2293
ethylene bisstearamide
HSDB 5398
Ethylene bis stearamide
Ethylene bis(stearamide)
EINECS 203-755-6
NSC 83613
N,N'-Ethylene bisstearamide
AI3-08515
N,N'-ethylene-bis-stearic amide
Abluwax EBS
Armowax EBS
Dorset WAX
C38H76N2O2
N,N'-ethylenebis
Glycowax 765
Kemamide W-39
Kemamide W-40
N,N'-1,2-Ethanediylbisoctadecanamide
Uniwax 1760
EC 203-755-6
Ethylene Bis Stearamide SF
SCHEMBL19975
Octadecanamide,N'-ethylenebis-
DTXSID4026840
NSC83613
MFCD00059224
NSC-83613
ZINC85733714
AKOS015915120
Octadecanamide,N'-1,2-ethanediylbis-
DS-6811
E0243
FT-0629590
V0595
D70357
N,N'-Ethylenebis(stearamide), beads, A802179
Q5404472
W-108690
2,5-dihexadecylhexanediamide
N,N'-(Ethane-1,2-diyl)distearamide
Plastic additive 03, European Pharmacopoeia (EP)
n,n'-ethylenebisoctadecanamide (mixture of fatty acid amides) (consists of c14, c16 and c18)
N,N'-Ethylenedi(stearamide)
1,2-Bis(stearoylamino) ethane
N,N′-1,2-Ethanediylbisoctadecanamide
Ethylene distearylamide
Ethylene bisstearamide
Ethylene distearamide
EBS
1,2- Bis(octadecanamido)ethane
Ethylenebisoctadecanamide
Ethylenebis(stearylamide)
Ethylenediamine bisstearamide
N-[2-(octadecanoylamino)ethyl]octadecanamide
N-(2-stearamidoethyl)stearamide
N,N'-Distearoylethylenediamine
N,N'-ethane-1,2-diyldioctadecanamide
N,N'-Ethylenedistearamide
n,n'-Ethylene distearylamide
Octadecanamide

Ethylene Carbonate
Acetoacetic ester; EAA; Ethyl beta-ketobutyrate; Acetoacetic ester, diacetic ether; Ethyl 3-oxobutanoate; Ethyl acetoacetate; Ethyl acetylacetate; 3-Oxobutanoic acid ethyl ester; Ethyl 3-ketobutyrate; Ethyl acetylacetate; Ethyl acetonecarboxylate; Ethylacetoacetat (German); Acetoacetato de metilo (Spanish); Acétoacétate de méthyle (French); cas no : 141-97-9
ETHYLENE DIAMINE
ETHYLENE DIOLEAMIDE, N° CAS : 110-31-6. Nom INCI : ETHYLENE DIOLEAMIDE. Nom chimique : N,N'-Ethane-1,2-diylbisoleamide. N° EINECS/ELINCS : 203-756-1. Ses fonctions (INCI) Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques
ETHYLENE DIOLEAMIDE
ETHYLENE DISTEARAMIDE, N° CAS : 110-30-5. Nom INCI : ETHYLENE DISTEARAMIDE. Nom chimique : N,N'-Ethylenedi(stearamide). N° EINECS/ELINCS : 203-755-6/931-299-4. Ses fonctions (INCI) : Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques
ETHYLENE DISTEARAMIDE
ETHYLENE DODECANEDIOATE, N° CAS : 54982-83-1, Nom INCI : ETHYLENE DODECANEDIOATE, Nom chimique : 1,4-Dioxacyclohexadecane-5,16-Dione, N° EINECS/ELINCS : 259-423-6, Ses fonctions (INCI). Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit. Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques
ETHYLENE DISTEARAMIDE
Ethylene Distearamide is a diamide.
Ethylene Distearamide (C38H76N2O2) is an organic compound otherwise called EBS.
Ethylene Distearamide is a waxy white solid that is also found in powder or bead form.


CAS Number: 110-30-5
EC Number: 203-755-6
MDL number: MFCD00059224
Molecular Formula: C38H76N2O2


Ethylene Distearamide (C38H76N2O2) is an organic compound otherwise called EBS.
Ethylene Distearamide is an organic compound with the formula (CH2NHC(O)C17H35)2.
Ethylene Distearamide is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.


Ethylene Distearamide is a synthetic wax with high melting point.
Ethylene Distearamide is a hard and brittle white high melting point wax.
Ethylene Distearamide is derived from the reaction of ethylenediamine and stearin.


Ethylene Distearamide is a waxy white solid that is also found in powder or bead form.
Ethylene Distearamide is an organic compound with the formula (CH2NHC(O)C17H35)2.
Ethylene Distearamide is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.


Ethylene Distearamide also functions as an external lubricant for PVC and a process aid for polyolefins.
Ethylene Distearamide is suitable for composites, styrenics and rubber.
Ethylene Distearamide has a shelf life of 365 days.


Ethylene Distearamide is also available in bead form.
Ethylene Distearamide is a secondary bis-amide additive.
Ethylene Distearamide has good anti-blocking properties in polyolefins.


Ethylene Distearamide powder is an amide wax of type N,N-bis-stearyl ethylenediamine with particularly good thermostability.
Ethylene Distearamide has no influence on the transparency of the Polymers.
Ethylene Distearamide is a widely used lubricant, high melting wax and white/yellow liquid.


Ethylene Distearamide is white or slight yellow powder or granule
Ethylene Distearamide is an organic compound with the formula (CH2NHC(O)C17H35)2.
Ethylene Distearamide is an amide wax.


Ethylene Distearamide has good compatibility applied in most of the plastics with the function of lubricating, dispersing, fusing, breaking, smoothing, anti-stick and anti-static.
Ethylene Distearamide is a white solid of low toxicity that provides a slippery coating for a variety of applications.


Ethylene Distearamide has excellent connectivity and dispersion on pigments and buffers.
Ethylene Distearamide is an organic compound with the formula (CH2NHC(O)C17H35)2.
Ethylene Distearamide is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.


Ethylene Distearamide is white spherical particle, non-toxic and no side effect on humans.
Ethylene Distearamide is insoluble in most organic solvents at room temperature.
Ethylene Distearamide is stable to acid, alkali and water medium.


Ethylene Distearamide is soluble in hot chlorinated hydrocarbons and aromatic hydrocarbon solvents.
Ethylene Distearamide is insoluble in organic solvents and water.
Ethylene Distearamide is soluble in high boiling solvents such as xylene, chloroform and butanol.


The flash point of Ethylene Distearamide is below 285°C and the density is 0.98 (25°C).
Synthhetic wax having high melting point, Ethylene Distearamide has some functions as internal and external lubricant, releasing and dispersion agent of pigment for the most thermosetting and thermoplastic resins.


Ethylene Distearamide is a synthetic wax made by combining two stearic acid molecules with one molecule of ethylenediamine.
Together the resulting Ethylene Distearamide is a white, waxy solid that is sold as a powder in various mesh sizes.
Ethylene Distearamide is an amide wax of type N,N-bis-stearyl ethylenediamine with particularly good thermostability.


Ethylene Distearamide is an amide wax of type Ethylene Distearamide.
Ethylene Distearamide acts as a slip and anti-block additive.
Ethylene Distearamide is based on a non-vegetable origin, secondary bis-amide.


Ethylene Distearamide is non-toxic, has no smell and is not soluble in water at room temperature. It has solubility in chlorinated or aromatic solvents.
The primary use for Ethylene Distearamide is as a release agent for PVC (poly-vinyl chloride) extrusion.
Ethylene Distearamide is compatible with styrene & styrenic copolymer, PVC, PO and PS.


Ethylene Distearamide exhibits good thermostability and excellent slip properties.
Ethylene Distearamide acts as both an internal and external lubricant to enhance malleability of the PVC resin.
Ethylene Distearamide is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.


Ethylene Distearamide will inherently lower the viscosity of the polymer resin and can decrease friction and abrasion of the polymer surface.
The recommended dosage levels are 500-2000 ppm in films and 0.2-1.0% in molding applications.
Ethylene Distearamide is EU 10/2011, FDA (175.105) and FDA (175.300) approved.


Ethylene Distearamide is ethylene-bis-stearamide of non-vegetable origin.
Ethylene Distearamide is a secondary bis amide effective as an anti-block agent and process aid for polyolefins.
Ethylene Distearamide is derived from the reaction of ethylenediamine and stearic acid.


Ethylene Distearamide is a white solid that provides a slippery coating for a variety of applications.
Ethylene Distearamide is also a dispersal agent and helps contribute to color uniformity and stability of the resulting extruded PVC product.
Adding Ethylene Distearamide to your thermoforming process will increase productivity by reducing shear stress.


Ethylene Distearamide is a white solid of low toxicity that provides a slippery coating for a variety of applications.
The overall product, Ethylene Distearamide, has a high gloss finish, smooth surface and increased tensile strength.
Overall, Ethylene Distearamide is an extremely cost effective and safe additive to use in the thermoplastic industry.


Ethylene Distearamide is used Chelated fertilizer, oil field chemicals.
Ethylene Distearamide is derived from the reaction of ethylenediamine and stearic acid.
Ethylene Distearamide's industrial products are slightly yellow particles or white powder, non-toxic, and have no side effects on the human body.


Ethylene Distearamide is derived from the reaction of ethylenediamine and stearic acid.
Ethylene Distearamide is a synthetic wax that has fatty amide groups that can interact with the surface of a variety of nanoparticles.
Ethylene Distearamide is derived from stearic acid and ethylenediamine.


Ethylene Distearamide is derived from the reaction of ethylenediamine and stearic acid.
Ethylene Distearamide by MLA Group has low acid value ( free fatty acid ), high melting point, and excellent white colour, and high purity.
Ethylene Distearamide offers mold release benefits in polyamides (nylon).


Ethylene Distearamide disperses evenly through the polymer in the melt phase, and migrates to the surface where it forms a thin lubricating layer that reduces coefficient of friction between surfaces and reduces unwanted adhesion.
Ethylene Distearamide has some functions as internal and external lubricant, releasing and dispersion agent of pigment for the most thermosetting and thermoplastic resins.


Ethylene Distearamide is a hard and brittle white high melting point wax, it's industrial products are slightly yellow fine particles, insoluble in most solvents at room temperature, stable to acids and bases, and aqueous media, soluble in hot chlorinated hydrocarbons and aromatic hydrocarbons solvents, it’s powder slippery feeling strong, above 80 ℃ to water with wettability of the compound.



USES and APPLICATIONS of ETHYLENE DISTEARAMIDE:
Ethylene Distearamide is used as a processing aid, dispersing agent and release agent.
In PVC applications and masterbatches the Ethylene Distearamide is used as an internal and external lubricant.
Ethylene Distearamide is used in the following areas: formulation of mixtures and/or re-packaging.


Ethylene Distearamide is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.


Ethylene Distearamide additive has high melting point and temperature stability.
This makes Ethylene Distearamide particularly suitable for the bitumen industry.
Ethylene Distearamide is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.


Because of its excellent lubricating properties Ethylene Distearamide is widely used internally and/or externally in most plastics such as ABS, PS, PP etc.
Adhesive pellets or film often develop adhesion between the polymer pellets or layers when exposed to elevated temperatures and pressures.
Ethylene Distearamide can be found in industrial use: in processing aids at industrial sites, formulation in materials and as processing aid.


Ethylene Distearamide is used in the following products: lubricants and greases, polymers, washing & cleaning products, inks and toners, metal working fluids, textile treatment products and dyes and coating products.
Ethylene Distearamide is paraffin-free.


Ethylene Distearamide is used in powder metallurgy.
Ethylene Distearamide, a new plastic lubricant developed in recent years, is widely used in the molding and processing of PVC products, ABS, high impact polystyrene, polyolefin, rubber and plastic products.


Ethylene Distearamide can be found in: outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).
Ethylene Distearamide provides optimized bitumen stability and is suitable for polymer-stabilized bitumens.


Due to Ethylene Distearamide's high melting point, the additive offers good thermal stability.
Ethylene Distearamide is a bis-amide polymer additive that lowers the temperature at which the asphalt softens.
Ethylene Distearamide is used as processing aid for resins and polymers and as defoaming agent.


Useful as defoamer for paper making and textile processing .
Ethylene Distearamide is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Ethylene Distearamide is used to prevent the adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.
Ethylene Distearamide is used Raw materials, Ethylenediamine Trap Stearic acid, Preparation Products, defoaming agent OTD.


Ethylene Distearamide is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.
Ethylene Distearamide is used in powder metallurgy.
Ethylene Distearamide is used as additive Ethylene Distearamide can be incorporated directly into polymers to prevent any unwanted adhesion.


Ethylene Distearamide can be found in products with material based on: rubber (e.g. tyres, shoes, toys) and fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys).
Ethylene Distearamide has proven mould release action in polyamides, and is a lubricant for PVC.
Ethylene Distearamide is used in the following products: washing & cleaning products, lubricants and greases, coating products, inks and toners and polishes


Ethylene Distearamide can be found in: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Ethylene Distearamide is used to lower the processing temperature and viscosity.


Ethylene Distearamide can be found in industrial use: formulation of mixtures, formulation in materials, as processing aid, manufacturing of the substance and in processing aids at industrial sites.
As a degassing agent it is used in powder coatings.


Ethylene Distearamide can be found in industrial use: in processing aids at industrial sites, as processing aid, in the production of articles, formulation in materials, formulation of mixtures and of substances in closed systems with minimal release.
Ethylene Distearamide is used as processing aid for resins and polymers and as defoaming agent.


Ethylene Distearamide is used for the manufacture of: rubber products and plastic products.
Ethylene Distearamide is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.


Ethylene Distearamide is traditionally used as lubricant and binder for cold compaction of powdered metal parts.
As Ethylene Distearamide has good wearable performance and smoothing performance, fits for improving polishing performance of lacquer, air release of surface with holes, Ethylene Distearamide is also well used as dulling agent for polishing furniture and printing ink.


Ethylene Distearamide is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.
Ethylene Distearamide is compared with traditional lubricants such as paraffin wax, polyethylene wax, stearate, etc.
Cosmetic Uses of Ethylene Distearamide: viscosity controlling agents


Ethylene Distearamide is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.
Ethylene Distearamide is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.


Ethylene Distearamide can also be used as a process aid, for example to improve dispersion of fillers.
Ethylene Distearamide is used as lubricant with good inner or outer lubricant action and has good coordination when used together with other lubricants as high grade alcohols, aliphatic acid esters, calcium stearate and paraffin.


Ethylene Distearamide is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.


Ethylene Distearamide not only has good external lubrication effect, but also has good internal lubrication effect, which improves the fluidity and demoulding property of melted plastic in plastic molding process, thus improving the yield of plastic processing, reducing energy consumption, and making the product obtain high surface smoothness and smoothness.


Ethylene Distearamide can help to increase the melting point of petroleum products; lubricant and corrosive agent of metal wire drawing.
Ethylene Distearamide is used in all types of industry, especially in the manufacture of plastics and paints, as a dispersing or lubricating agent to facilitate and stabilize the dispersion of materials in mixtures, to reduce friction and abrasion of the surface of polymers, or to contribute to color stability.


Ethylene Distearamide is added in the coating production to increase the uniform dispersion of pigment and filler, improve the surface leveling property of baking paint, prevent the stripping off of paint film and improve water-proof and acid-resistant and alkali-resistant property.
Other Industrial Uses of Ethylene Distearamide: Modifier Used in Asphalt Production to Lower the Temperature at Which the Asphalt Will Soften.


Ethylene Distearamide is a bis-amide anti-blocking additive used to prevent blocking and as anti-tack of adhesives.
Ethylene Distearamide is used in the following products: washing & cleaning products, lubricants and greases, coating products, inks and toners and polishes and waxes.


Ethylene Distearamide is used in the following products: polymers, lubricants and greases, metal working fluids, pharmaceuticals and cosmetics and personal care products.
Ethylene Distearamide is non-toxic and can be dispersed evenly through the polymer in the melt phase.


Ethylene Distearamide is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.
Because of it's excellent lubricating properties, Ethylene Distearamide is widely used internally and/or externally in most plastics such as ABS, PS, PP etc.


Ethylene Distearamide is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.
Slip- and anti-blocking agent for polyolefins and PVC, especially for film applications and also lubricant for wood plastic composites and plastics.


Ethylene Distearamide is useed Anti-Blocking Agent, Release Agent, Slip Agent, Flow Promoter, and Hot-Melt Adhesive.
In nitrocellulose lacquers, Ethylene Distearamide can bring about the flatting action.
Experience has shown that simple manual mixing prior to processing will normally give an acceptable dispersion though, mechanical means are preferred.


Ethylene Distearamide is used as lubricant in powder metallurgy (PM) steels to reduce the inter-particle and die-wall friction during pressing and hence improve powder compressibility and ejection of the component from the compaction tool.
Ethylene Distearamide is a lubricant widely used in molding and processing of PVC, ABS, high-impact polystyrene, polyolefin, rubber and plastic products.


Ethylene Distearamide is also used in processing industries, for example in the paper industry and the powder metallurgy sector, as a release agent, as an antistatic agent and an anti-foam agent for the production of thermoplastics , cables and paper.
Ethylene Distearamide is used for the manufacture of: rubber products, textile, leather or fur, machinery and vehicles and chemicals.


Ethylene Distearamide is high melting wax and white/yellow liquid.
Ethylene Distearamide is used in the following products: polymers, lubricants and greases, metal working fluids, pharmaceuticals and cosmetics and personal care products.


In synthetic fiber industry, Ethylene Distearamide can improve the heat-resistant, weather-resistant property of polyester and polyamide and bring about certain antistatic effects.
Ethylene Distearamide is traditionally used as lubricant and binder for cold compaction of powdered metal parts.


Compared with traditional lubricants such as paraffin wax, polyethylene wax and stearate, Ethylene Distearamide not only has good external lubricity, but also has good internal compatibility, applied in most plastics with good function lubricating, dispersing, fusing, breaking, smoothing, anti-stick and anti-static properties.


Ethylene Distearamide is used in the following areas: formulation of mixtures and/or re-packaging and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Ethylene Distearamide is used for the manufacture of: rubber products, textile, leather or fur, machinery and vehicles and chemicals.


Ethylene Distearamide is used as a processing aid for resins and polymers and as a defoaming agent.
As Ethylene Distearamide has strong cohesions with pigment or other filler, Ethylene Distearamide can improve the dispersion and coupling property of fillers in the polymers to enhance the commercial value of the products.


Ethylene Distearamide is used as defoamer/ anti-foaming agent and coating component of paper for paper-making industry.
Added in the manufacturing process of dope and oil paint to enhance salt mist and dampproof effect and to improve performance of paint remover.
Ethylene Distearamide is used in powder metallurgy.


Ethylene Distearamide is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.
Ethylene Distearamide improves the kneading, processing and vulcanization performance of rubber grains in the processing of rubber.
Ethylene Distearamide derived from stearic acid with ethylene diamine is a synthetic was used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability.


Ethylene Distearamide is also used as release agents, antistatic agents, and antifoaming agents.
Ethylene Distearamide can be used for a wide range of applications such as lubricants, activators and dispersing agents that reduce the friction in the system and increase the rate of processing.


Ethylene Distearamide is used Lubricant in powder metal molding, rubber, adhesives, coatings, wire drawing, wood plastic composite, Defoamer in paper, Lubricant for Polyacetals, Water repellent for paper, Intermediate for defoamers, and Delustering agent for furniture finishes and printing inks.
Ethylene Distearamide has excellent connectivity and dispersion on pigments and buffers.


Ethylene Distearamide can also be used as a process aid, for example to improve dispersion of fillers.
Ethylene Distearamide is a bis-amide polymer additive that lowers the temperature at which the asphalt softens.
Ethylene Distearamide is used in the following areas: formulation of mixtures and/or re-packaging.


Ethylene Distearamide is used for the manufacture of: rubber products and plastic products.
Ethylene Distearamide can be found in: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).


Ethylene Distearamide is soluble in high boiling solvents such as xylene, chloroform and butanol.
Ethylene Distearamide is an effective lubricant, processing aid, slip additive and pigment dispersant aid for most polymers.
Ethylene Distearamide is also used as a release agents, antistats, and antifoaming agent.


Ethylene Distearamide is an ethylenebisstearamide, specifically developed to afford low, consistent viscosities and superior cost performance in paper pulp defoamer applications.
Ethylene Distearamide provides typical slip and anti blocking characteristics to all polymers.


Ethylene Distearamide powder does not affect the transparency of polymers and acts as lubricant in a wide variety of polymers like PVC, PO, PS and engineering plastics.
Ethylene Distearamide is used as Release agent and flow promoter for all engineering resins, Styrenics and their copolymers


Ethylene Distearamide is used Dispersing agent for masterbatch applications, preferably for engineering resins and PVC, and Modifier in textile auxiliaries.
An addition of 0.5-1 % of Ethylene Distearamide can not only prevent the occurrence of air bubbles but also make the plastic bags be slippery so as to be opened easily.


Ethylene Distearamide can remarkably enhance the heat-resistant and weather-resistant properties while coordinating with chief stabilizer in formulation of inorganic filler for PVC and polyolefin.
Ethylene Distearamide is used as anti-adhesive agent for various polymer film or sheets.


Ethylene Distearamide is used as nucleation transparency agent to reduce the nucleating time in compounds such as polyolefins, polyformaldehyde and polyamide, promote the structure of resin to become fine, thus improve the mechanical property and transparency of the products.
Ethylene Distearamide is used as processing auxiliary of rubber. Besides the lubricant demoulding property and modifying performance of filler surface,

Ethylene Distearamide can raise the surface fineness of rubber pipes and rubber plates to act as rubber surface polishing agent.
Ethylene Distearamide is not just for PVC thermoforming, it is suitable as an additive for nearly any thermoplastic manipulation with benefits similar to those described above for the PVC process.


Ethylene Distearamide is used in the spinning of antistatic nylon fiber as additive and also is able to reduce the breaking of yarn.
Ethylene Distearamide can be used with ABS, polystyrene, polyethylene, polypropylene and more.
Ethylene Distearamide is used in the following products: adhesives and sealants, lubricants and greases, coating products, polishes and waxes and washing & cleaning products.


Ethylene Distearamide migrates to the surface of the polymer where it forms a thin lubricating layer.
Ethylene Distearamide is used in the following products: adhesives and sealants, lubricants and greases, coating products, polishes and waxes and washing & cleaning products.


Ethylene Distearamide is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.


In plastic masterbatch applications Ethylene Distearamide reduces the amount of resin/binder necessary which translates to cost savings.
Ethylene Distearamide can help to increase the smoothness and fineness for insulator layer of electric power and cable.
Ethylene Distearamide is added to oil based defoamers to improve foam knock down.


Ethylene Distearamide can also be used as a process aid, for example to improve dispersion of fillers.
Ethylene Distearamide improves flow and has no influence on transparency of polymers.
Ethylene Distearamide acts as a lubricant, release & antiblocking agent for all engineering resins and dispersing agent for masterbatch applications.


Because of it's excellent lubricating properties, Ethylene Distearamide is widely used internally and/or externally in most plastics such as ABS, PS, PP, etc.
Ethylene Distearamide is used as additive Ethylenebisstearamide can be incorporated directly into polymers to prevent any unwanted adhesion.
Ethylene Distearamide can also be a binder in the precise engineering metal part.


Due to it's good dispersing ability and surface migration Ethylene Distearamide can be used in printing inks.
A field of application is the bitumen industry: When used in asphalt binder for road making (asphalt modifiers), Ethylene Distearamide increases its softening point and enhances its visco-elasticity.


Ethylene Distearamide can decrease the viscosity of asphalt and improve it’s softening point and weathering resistance when added to asphalt.
Ethylene Distearamide can also be used as a process aid, for example to improve dispersion of fillers.
Ethylene Distearamide is used as an additive for hot melt adhesives.


Lubrication performance is excellent, anti-calcium salt ability is strong, drag reduction effect is good, used for drilling in saturated brine to reduce power consumption.
Ethylene Distearamide is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits.


Ethylene Distearamide is an internal additive and can be incorporated into resin as supplied or via masterbatch / pre-blend.
Ethylene Distearamide is used for lubricant of plastic and metal molding, adhesion preventives, viscosity modifier, anti-corrosion of wax, water resistance of coating and spray paint.


In the processing of ABS, AS, hard PVC, polyformaldehyde, polycarbonate, polyurethane and phenolformaldehyde resins, Ethylene Distearamide is used as lubricant demoulding agent with a quantity of 0.5~1.5 %.
Ethylene Distearamide will also help with pigment dispersal and give the finished product a more vibrant glossy finish.


Typical addition levels vary depending on polymer and lubrication required.
Ethylene Distearamide acts as a slip and anti-block agent, mold release agent and lubricant for PVC.
Dispersing agent for masterbatch applications, preferably for engineering resins and PVC.


Ethylene Distearamide provides typical slip and anti blocking characteristics to all polymers e.g. in films.
Ethylene Distearamide has proven mold release benefits in nylon and is a lubricant for PVC.
Application of Ethylene Distearamide: Water treatment


Ethylene Distearamide is used as an internal and external slip agent in many thermoplastic and thermosetting plastics, the most representative ones are ABS, PS, ABS, PVC, also used in PE, PP, PVAC, cellulose, Accurate, Nylon, phenolic-Resin, amino plastics.
Ethylene Distearamidehas a good finish and good film release.


As a lubricant of polyformaldehyde, the addition amount is 0.5%, which improves the melt flow rate and the film release, and the whiteness, thermal stability and physical index of polyformaldehyde all reach the superior index.
Chemical fiber: Ethylene Distearamide can improve the heat and weather resistance, fluidity of polyester, polyamide fiber, and give a certain anti-static effect.


Release agent: Phenolic resin for sand casting with Ethylene Distearamide can be used as a release agent.
Powder Coating: Ethylene Distearamide can be used as flow additives for powder coatings.
Hot-Melt Adhesive Applications of Ethylene Distearamide: Release agent and flow promoter for all engineering resins, Styrenics and their copolymers.


Chemical fiber: Ethylene Distearamide can improve heat and weather resistance performance of polyester and polyamide fiber, and has some anti-static effect.
Pigment and filler: Ethylene Distearamide can be used as pigment dispersant of plastic , fiber, such as ABS, PS, polypropylene fibre and PET fiber and other color masterbatch.


Ethylene Distearamide is used as additive EBS can be incorporated directly into polymers to prevent any unwanted adhesion.
Adhesive pellets or film often develop adhesion between the polymer pellets or layers when exposed to elevated temperatures and pressures.


When manufacturing coating and painting, Ethylene Distearamide can improve the effect of salt spray and moistureproof by adding Ethylene Distearamide.
Ethylene Distearamide can help to improve the paint stripper performance of paint when added, and to increase the leveling performance of baking enamel varnish.


-Uses & Applications
*Flow Enhancer in Powder Coating Additives
*Metal Working Fluids
*Friction Reducing Lubricant in Wire-Drawing
*Plastics
*Internal and External Lubricant, Pigment Stabilizer and Dispersant in the Processing of all Types of Plastics
*Imparts a Smooth Gloss Finish to Rigid PVC
*Improves the General Surface Appearance of Most Plastics.
*The Multiple Functions of EBS in Plastics Production Improve Processing Time and Reduce Processing Costs
*Rubber
*Release Agent and Additive to the Surface Finishing in the Production of Rubber
*Textiles and Paper
*Anti-Static Agent and Anti-Foaming Agent in Paper and Textile


-Paint, Ink:
*Adding 0.5~2% Ethylene Distearamide can improve the effect of salt spray and moisture resistance in the manufacture of paint and lacquer.
*Adding Ethylene Distearamide in the paint can improve the performance of the paint stripper and can improve the leveling of the baked enamel surface.
*Ethylene Distearamide can be used as a matting agent in furniture polishing agents and printing ink.
*After micronization (particle size: d50 about 6μ, d 90 about 12μ), Ethylene Distearamide has excellent anti-abrasion and smoothness and can be used in lacquer systems to improve polishability and degassing on a porous surface.


-Applications of Ethylene Distearamide:
*Adhesives & sealants
*Composites
*Inks


-Mode of action:
Ethylene Distearamide can be dispersed evenly through the polymer in the melt phase.
Ethylene Distearamide migrates to the surface of the polymer where it forms a thin lubricating layer.
This layer reduces the coefficient of friction between surfaces and prevents any unwanted adhesion.


-Other uses of Ethylene Distearamide:
*Melting point rising agent for petroleum products
*Lubricant and anti-corrosion agent for metal drawing
*Potting material for electrical components; defoaming agent and paper coating ingredient for paper industry
*Ethylene Distearamide is used as a defoaming agent and permanent water pulling agent for dyeing works in textile dyeing and finishing
*Adding this product in asphalt can reduce the viscosity of asphalt and improve the softening point, water-resistance and weather resistance of asphalt.


-Pigment, filler dispersant:
*Ethylene Distearamide is used as a pigment dispersant for plastic.
*Pigment dispersant for chemical fiber masterbatches, such as ABS, PS, polypropylene, polyester masterbatches.
*Ethylene Distearamide can also be used as diffusion powder for plastic color matching.
*Depending on the amount of pigment and filler added, the addition amount is 0.5~5%.


-Consumer Goods:
*Appliances & Electronics
*Adhesives & Sealants: Industrial & *Assembly Adhesives
*Electronics Adhesives
*Industrial Manufacturing
*Healthcare & Pharma — Medical
*Medical Tapes & Adhesives
*Electrical & Electronics — Packaging & Assembly
*Adhesives & Sealants
*Adhesive & Sealant Type


-Rubber:
Synthetic resin and rubber will have good anti-adhesive and anti-caking effect by adding Ethylene Distearamide in their emulsion.
Ethylene Distearamide has a good effect to the increase surface gloss when added to rubber products.


-Plastic uses of Ethylene Distearamide:
Lubricants inside or outside many plastics such as ABS, PS, AS, PVC, PE, PP, PVAC, cellulose acetate, nylon, phenolic resin and amino plastics.
Ethylene Distearamide has a good surface quality and demoulding performance.


-Rubber:
Synthetic resins and rubber such as Vinyl, polychloroprene, GRS (SBR) add 1~3% EBS to their emulsions, it has a good anti-viscosity and anti-caking effect, EBS is used in floor mats for automobiles, drainage pipes, and other rubber products to increase the effect of surface gloss.



PROPERTIES OF ETHYLENE DISTEARAMIDE:
– Release agent
– lubricant
– dispersing agent
– Anti-foaming
– Anti-static



BENEFITS of ETHYLENE DISTEARAMIDE:
-Excellent slip and anti-blocking properties when used in PVC, engeneering resins, PO film and compounds
-Good release properties in PVC and thermoplastics
-Improves flow of polymers
-No influence on transparency of polymers
-Wide food approval



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENE DISTEARAMIDE:
Appearance: White, waxy crystals
Odor: Odourless
Melting point: 144 to 146 °C (291 to 295 °F; 417 to 419 K)
Flash point: 280 °C (536 °F; 553 K)
Physical state: Beads
Color: white
Odor: odorless
Melting point/range: 144 - 146 °C - lit.
Initial boiling point and boiling range: 260 °C at 1.013 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: ca.270 °C - DIN 51758
Autoignition temperature: ca.380 °C at 1.013 hPa - DIN 51794
Decomposition temperature: > 200 °C -
pH: No data available
Viscosity Viscosity, kinematic: No data available
Viscosity, dynamic: ca.10 mPa.s at 150 °C
Water solubility at 20 °C: insoluble

Partition coefficient: n-octanol/water log Pow: 13,98 at 25 °C
Vapor pressure: Not applicable
Density: 1 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 720.34 °C. @ 760.00 mm Hg (est)
Flash Point: 213.00 °F. TCC ( 100.70 °C. ) (est)
logP (o/w): 14.787 (est)
Soluble in: water, 2.049e-010 mg/L @ 25 °C (est)

Molecular Weight: 593.0
XLogP3-AA: 15.7
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 35
Exact Mass: 592.59067967
Monoisotopic Mass: 592.59067967
Topological Polar Surface Area: 58.2 Ų
Heavy Atom Count: 42
Formal Charge: 0
Complexity: 503
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Melting point: 144-146 °C(lit.)
Boiling point: 646.41°C (rough estimate)
Density: 1 g/cm3 (20℃)
vapor pressure: 0.000023 Pa (20 °C)
refractive index: 1.4670 (estimate)
Flash point: 280℃
storage temp.: 2-8°C
solubility: ketones, alcohols and aromatic solvents at their boiling points: soluble
pka: 15.53±0.46(Predicted)
form: beads
Appearance: Powdery
Smell: No smell
Color (Gardner): ≤3#
Melting Point (℃): 141.5-146.5
Acid Value (mgKOH/g): ≤7.50
Amine value (mgKOH/g): ≤2.50
Moisture (wt%): ≤0.30
Mechanical impurity: Φ0.1-0.2mm(individual/10g)



FIRST AID MEASURES of ETHYLENE DISTEARAMIDE:
-Description of first-aid measures:
*After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*After swallowing:
Make victim drink water (two glasses at most).
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ETHYLENE DISTEARAMIDE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of ETHYLENE DISTEARAMIDE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENE DISTEARAMIDE:
-Control parameters
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ETHYLENE DISTEARAMIDE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of ETHYLENE DISTEARAMIDE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



SYNONYMS:
1,2-BIS(OCTADECANAMIDO)ETHANE
1,2-ETHYLENEBIS(STEARAMIDE)
ABRIL WAX 10DS
ACRAWAX C
ADVAWAX
ARMOWAX EBS-P
BIS(STEAROYL)ETHYLENEDIAMIDE
CARLISLE WAX 280
CHEMETRON 100
ETHYLENE BIS STEARAMIDE
ETHYLENE DISTEARAMIDE
ETHYLENE DISTEARAMIDE [INCI]
ETHYLENEBIS (STEARAMIDE )
ETHYLENEBIS(STEARIC ACID AMIDE)
ETHYLENEDIAMINE BIS(STEARAMIDE)
KEMAMIDE W 40
LIPOWAX C
LUBROL EA
MICROTOMIC 280
N,N-ethylenedi(stearamide)
1,2-distearamidoethane
N,N-Ethylenebisoctadecanamide
N,N'-ethylene bis-stearamide
N,N'-ethane-1,2-diyldioctadecanamide
2,5-dihexadecylhexanediamide
1,2-Bis(stearoylamino) ethane
N,N′-1,2-Ethanediylbisoctadecanamide
N,N′-Ethylenedi(stearamide)
Ethylene distearylamide
N,N′-(Ethane-1,2-diyl)di(octadecanamide)
ETHYLENE-BIS-STEARAMIDE
waxc
EBSA
advawax
acrawaxc
acrowaxc
lubrolea
5-AC-13C4
acrawaxct
110-30-5
N,N'-Ethylenebis(stearamide)
Plastflow
Ethylene distearamide
N,N'-(Ethane-1,2-diyl)distearamide
Advawax
Acrowax C
Acrawax CT
Lubrol EA
Ethylenedistearamide
Microtomic 280
Advawachs 280
Ethylenebis(stearylamide)
Abril wax 10DS
Carlisle 280
Nopcowax 22-DS
Ethylenebisstearoamide
Advawax 275
Advawax 280
Carlisle Wax 280
Armowax ebs-P
Ethylenebis(stearamide)
Octadecanamide, N,N'-1,2-ethanediylbis-
N,N'-Ethylenebisoctadecanamide
1,2-Bis(octadecanamido)ethane
Chemetron 100
N,N'-ETHYLENE DISTEARYLAMIDE
N,N'-Ethylenedistearamide
Ethylenediamine steardiamide
Ethylenediamine bisstearamide
N,N'-Distearoylethylenediamine
Ethylenebisstearamide
N,N'-Ethylenebisstearamide
NN'-Ethylenebis(stearamide)
Stearic acid, ethylenediamine diamide
Ethylenebisoctadecanamide
Octadecanamide, N,N'-ethylenebis-
UNII-603RP8TB9A
N-[2-(octadecanoylamino)ethyl]octadecanamide
N,N-Ethylenebis(stearamide)
603RP8TB9A
N,N'-ethane-1,2-diyldioctadecanamide
Acrawax C
Kemamide W 40
N,N'-Ethylenedi(stearamide)
WAX C
N,N-Ethylenebisstearamide
CCRIS 2293
ethylene bisstearamide
HSDB 5398
Ethylene bis stearamide
Ethylene bis(stearamide)
EINECS 203-755-6
NSC 83613
N,N'-Ethylene bisstearamide
AI3-08515
N,N'-ethylene-bis-stearic amide
Abluwax EBS
Armowax EBS
Dorset WAX
C38H76N2O2
N,N'-ethylenebis
Glycowax 765
Kemamide W-39
Kemamide W-40
N,N'-1,2-Ethanediylbisoctadecanamide
Uniwax 1760
EC 203-755-6
Ethylene Bis Stearamide SF
SCHEMBL19975
Octadecanamide,N'-ethylenebis-
DTXSID4026840
NSC83613
MFCD00059224
NSC-83613
ZINC85733714
AKOS015915120
Octadecanamide,N'-1,2-ethanediylbis-
DS-6811
E0243
FT-0629590
V0595
D70357
N,N'-Ethylenebis(stearamide), beads, A802179
Q5404472
W-108690
2,5-dihexadecylhexanediamide
N,N'-(Ethane-1,2-diyl)distearamide
Plastic additive 03, European Pharmacopoeia (EP)
n,n'-ethylenebisoctadecanamide (mixture of fatty acid amides) (consists of c14, c16 and c18)
N,N'-Ethylenedi(stearamide)
1,2-Bis(stearoylamino) ethane
N,N′-1,2-Ethanediylbisoctadecanamide
Ethylene distearylamide
Ethylene bisstearamide
Ethylene distearamide
EBS
1,2- Bis(octadecanamido)ethane
Ethylenebisoctadecanamide
Ethylenebis(stearylamide)
Ethylenediamine bisstearamide
N-[2-(octadecanoylamino)ethyl]octadecanamide
N-(2-stearamidoethyl)stearamide
N,N'-Distearoylethylenediamine
N,N'-ethane-1,2-diyldioctadecanamide
N,N'-Ethylenedistearamide
n,n'-Ethylene distearylamide
Octadecanamide
N,N'-1,2-ETHANEDIYLBISOCTADECANAMIDE
N,N'-BIS(OCTADECANOYL)ETHYLENEDIAMINE
N,N'-DIST EAROYLETHYLENEDIAMINE
N, N'-ETHYLENE BISSTEARAMIDE
N,N'-ETHYLENE DISTEARYLAMIDE
N,N'-ETHYLENE DISTEARYLAMIDE [HSDB]
N,N'-ETHYLENEBIS(STEARAMIDE)
N,N'-ETHYLENEBIS(STEARIC AMIDE)
N,N'-ETHYLENEDISTEARYLAMIDE
NOPCOWAX 22-DS
NSC-83613
OCTADECANAMIDE, N,N'-1 ,2-ETHANEDIYLBIS-
OCTADECANAMIDE, N,N'-ETHYLENEBIS-
PLASTFLOW
STEARIC ACID, ETHYLENE DIAMINE DIAMIDE
WAX C


ETHYLENE DISTEARYLAMIDE (EBS)
Ethylene distearylamide ( EBS) is a synthetic wax that has fatty amide groups that can interact with the surface of a variety of nanoparticles.
Ethylene distearylamide ( EBS) can be used for a wide range of applications such as lubricants, activators and dispersing agents that reduce the friction in the system and increase the rate of processing.
Ethylene distearylamide ( EBS) is an organic compound with the formula (CH2NHC(O)C17H35)2.

CAS: 110-30-5
MF: C38H76N2O2
MW: 593.02
EINECS: 203-755-6

Ethylene distearylamide ( EBS) is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.
Ethylene distearylamide ( EBS) is derived from the reaction of ethylenediamine and stearic acid.
Ethylene distearylamide ( EBS) is a white solid of low toxicity that provides a slippery coating for a variety of applications.

Ethylene distearylamide ( EBS) Chemical Properties
Melting point: 144-146 °C(lit.)
Boiling point: 646.41°C (rough estimate)
Density: 1 g/cm3 (20℃)
Vapor pressure: 0.000023 Pa (20 °C)
Refractive index: 1.4670 (estimate)
Fp: 280℃
Storage temp.: 2-8°C
Solubility: ketones, alcohols and aromatic solvents at their boiling points: soluble
Form: beads
Pka: 15.53±0.46(Predicted)
Water Solubility: 0ng/L at 25℃
InChIKey: RKISUIUJZGSLEV-UHFFFAOYSA-N
LogP: 13.98 at 25℃
CAS DataBase Reference: 110-30-5(CAS DataBase Reference)
EPA Substance Registry System: Ethylene distearylamide ( EBS) (110-30-5)

Uses
Ethylene distearylamide ( EBS) is a bis-amide polymer additive that lowers the temperature at which the asphalt softens.
Ethylene distearylamide ( EBS) is used as processing aid for resins and polymers and as defoaming agent.
Ethylene distearylamide ( EBS) is traditionally used as lubricant and binder for cold compaction of powdered metal parts.
Ethylene distearylamide ( EBS) is a bis-amide polymer additive that lowers the temperature at which the asphalt softens
Ethylene distearylamide ( EBS) is used as processing aid for resins and polymers and as defoaming agent.
Ethylene distearylamide ( EBS) is traditionally used as lubricant and binder for cold compaction of powdered metal parts.
Ethylene distearylamide ( EBS) is an effective lubricant, processing aid, slip additive and pigment dispersant aid for most polymers.
Ethylene distearylamide ( EBS) is an ethylenebisstearamide, specifically developed to afford low, consistent viscosities and superior cost performance in paper pulp defoamer applications.
Useful as defoamer for paper making and textile processing.

Ethylene distearylamide ( EBS) is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.
Ethylene distearylamide ( EBS) is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.
Ethylene distearylamide ( EBS) is used in powder metallurgy.

Synonyms
N,N'-ETHYLENEBISSTEARAMIDE
N,N'-ETHYLENEBISOCTADECANAMIDE
1,2-bis(octadecanamido)ethane
abrilwax10ds
Glyco(R) Asphalt Modifier beads
Acrawax(R) C atomized
N, N` Distearoylethyelendiamine
Acrawax(R) C beads
ETHYLENE DODECANEDIOATE
Ethylene glycol; ethyleneglycol ; Ethanediol; Ethane-1,2-diol; ethanediol; ethylene glycol; GLYCOL, N° CAS : 107-21-1. Nom INCI : GLYCOL. Nom chimique : Ethane-1,2-diol, Ethylene glycol. N° EINECS/ELINCS : 203-473-3. Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau. Solvant : Dissout d'autres substances. Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques. Principaux synonymes. Noms français : 1,2-DIHYDROXYETHANE; 2-HYDROXYETHANOL; ETHANE-1,2-DIOL; ETHANEDIOL-1,2; ETHYLENE ALCOHOL; Glycol d'éthylène; Monoéthylène glycol; Éthylène glycol. Noms anglais : 1,2-Ethanediol; Ethylene glycol. Utilisation: L'éthylène glycol est surtout utilisé : comme composé antigel ou liquide de transfert de chaleur que ce soit pour les radiateurs d'automobiles, les systèmes de refroidissement industriels ou le dégivrage des avions; comme matière première pour la synthèse de fibre de polyester, de films et de résines. Il sert aussi : de solvant dans les peintures au latex, les encres et les adhésifs; d'agent de déshydratation dans le traitement du gaz naturel; dans les formulations de produits pharmaceutiques, comme substitut de la glycérine; dans les préparations de fluides pour transmissions hydrauliques; dans les condensateurs électrolytiques, comme solvant de suspension pour le perborate d'ammonium; pour la fabrication d'explosifs. Translated names 1,2-Etaanidioli; etyleeniglykoli (fi); 1,2-etandiol (no); 1,2-etandiolis (lt); 1,2-ethaandiol (nl); 1,2-ethandiol (da); Etaandiool (et); etandiol (hr); etano-1,2-diol (pl); etanodiol (es); ethan-1,2-diol (cs); Ethandiol (de); ethylenglycol (da); ethylenglykol (cs); etilen glicol (it); etilen-glikol (hr); etilenglicol (es); etilenglikolis (lt); etilenoglicol (pt); etilén-glikol (hu); etilēnglikols (lv); etylenglykol (no); etylénglykol (sk); etán-1,2-diol (hu);Etüleenglükool (et); etāndiols (lv); glicol etilenico (it); glikol (sl); glikol etylenowy (pl); glykol (da); éthylène-glycol (fr); αιθυλενογλυκόλη γλυκόλ (el); етандиол (bg); етилен гликол (bg) CAS names: 1,2-Ethanediol; : 1,2 ethanediol; 1,2-Dihydroxyethane; 1,2-etandiolo; 1,2-ETHANE DIOL; 1,2-ETHANE DIOL1,2-Ethanediol2,2'-oxydiethanolBio MEG.Ethane-1,2-diolEthanediol; Ethylene glycol; ethane-1,2-diolEthanol-1,2-diolEthylene GlycolMEGMono Ethylene Glycol; Monoethylen glycol; MONOETHYLENE GLYCOL; Monoethyleneglycol; Monoethylenglykol; Monothylene Glycol; 1,2-Ethanediol, glycol; 1.2-Ethanediol; 2,2'-oxydiethanol; Bio MEG; CH2OHCH2OH; enthanediolethylene glycole; Ethane-1,2-diol; Ethane -1,2-diol; Ethane 1,2 diol; ethane-1,2-diol/ethylene glycol; ethanediol / ethylene glycol; ethanediol ethylene glycol; Ethanediol; Ethylene glycol; ethane-1,2-diol; ethaneglycol; Ethanol-1,2-diol; Ethylen glycol; ethylene glycol polyester grade;ETHYLENE GLYCOL; 1,2-ethanediol; glycol ; Ethylene glycol; Glycol; Ethylene-glycol; Età-1,2-diol; MEG; mono ethylene glycol; Monoethyleenglycol; Monoethylene glycol; Monoethyleneglycol; Monoethyleneglykol; Monoethylenglycol; Monoethylenglykol; Reaction mass of 64-17-5 and 7732-18-5; Ethanediol Trade names 1,2-Ethylene glycol 1-2 Ethane-diol 2-Hydroxyethanol Adiprene LF 1869A Adiprenes Bio-MEG EG Ethylene alcohol Ethylene dihydrate Ethylene Glycol Antifreeze Grade ETHYLENE GLYCOL INDUSTRIAL GRADE ethylene glycol water blend Ethylene glyvol Ethyleneglykol Fomrez. Glycol Glycol alcohol MEG Fibre MEG Industrial MEG Normal Mono ethyelene Glycol Mono Ethylene Glycol HP Monoethylene Glycol (MEG) MONOETHYLENE GLYCOL, MEG Monoetilenglicol grado fibra Monoetilenglicol grado industrial
Ethylene glycol
1,2-Ethanediol; Ethylene alcohol; Hypodicarbonous acid; Monoethylene glycol; 1,2-Dihydroxyethane cas no: 107-21-1
Ethylene glycol ( Monoéthylène glycol)
Glycol Distearate; Ethylene Glycol Dioctadecanoate; Octadecanoic Acid, 1,2-Ethanediyl Ester; Ethylene Dioctadecanoate; 1,2-Ethanediyl Octadecanoate CAS NO:627-83-8
ETHYLENE GLYCOL DIHYDROXY DIMETHYL ETHER
DESCRIPTION:

Ethylene Glycol Dihydroxy Dimethyl Ether, a hydrophilic ether,[1] is an electron-donor solvent.
Its toxicity has been assessed.
The effect of complexation of diglyme with lithium trifluoromethanesulfonate on the conformation has been investigated.
Ethylene Glycol Dihydroxy Dimethyl Ether is reported to enhance the ability of KF-MeOH-Al2O3 (potassium fluoride-methanol-alumina) reagent to replace halogen with methoxy groups in 5,8-dihydroxy-2,3-dichloro-1,4-naphthoquinones.


CAS Number: 111-96-6
EC Number: 203-924-4
Molecular Weight: 134.17
Beilstein: 1736101
Linear Formula: (CH3OCH2CH2)2O


SYNONYM(S):
2-Methoxyethyl ether, Bis(2-methoxyethyl) ether, Dimethyldiglycol, ‘Diglyme’,2,2′-Oxybis(ethan-1-ol),2-(2-Hydroxyethoxy)ethan-1-ol,Diethylene glycol,Ethylene diglycol,Diglycol,2,2′-Oxybisethanol,2,2′-Oxydiethanol,3-Oxa-1,5-pentanediol,Dihydroxy diethyl ether,Digenos,Digol,Ethylene glycol bis-mercaptoacetate,diethylene glycol, 2,2'-oxydiethanol, diglycol, diethylenglykol, 2-hydroxyethyl ether, bis 2-hydroxyethyl ether, ethanol, 2,2'-oxybis, 2,2'-oxybisethanol, 2-2-hydroxyethoxy ethanol, digol,(2-hydroxyethoxy) ethan-2-ol,2,2'-oxydiethanol,2,2'-Dihydroxydiethyl ether,2,2'-Oxybis[ethano],2,2'-Oxydiethanol,2,2'-Oxyethanol,2- hydroxyethoxy)ethan- 2-ol,2-(2-Hydroxyethoxy)ethanol,3-Oxapentamethylene-1,5-diol,3-Oxapentane-1,5-diol,(2-hydroxyethyl) ether,Bis(2-hydroxyethyl)ether,Bis(β-hydroxyethyl) ether,DIETHYLENE GLYCOL,111-46-6,2,2'-Oxydiethanol,Diglycol,2,2'-Oxybisethanol,2-(2-Hydroxyethoxy)ethanol,Diethylenglykol,Digol,2-Hydroxyethyl ether,Bis(2-hydroxyethyl) ether,DI(HYDROXYETHYL)ETHER,Ethanol, 2,2'-oxybis-,Digenol,Dicol,Brecolane ndg,Glycol ether,Deactivator E,Dissolvant APV,Ethylene diglycol,2,2'-Oxyethanol,1,5-Dihydroxy-3-oxapentane,Diethyleneglycol,TL4N,3-Oxapentane-1,5-diol,Dihydroxydiethyl ether,2,2'-0xydiethanol,Bis(beta-hydroxyethyl) ether,2,2'-Dihydroxydiethyl ether,Ethanol, 2,2'-oxydi-,2-(2-hydroxyethoxy)ethan-1-ol,2,2'-Dihydroxyethyl ether,beta,beta'-Dihydroxydiethyl ether,Deactivator H,Caswell No. 338A,2,2'-Oxybis(ethan-1-ol),3-Oxapentamethylene-1,5-diol,3-Oxa-1,5-pentanediol,DEG,HSDB 69,NSC 36391,CCRIS 2193,DTXSID8020462,bis(2-hydroxyethyl)ether,EINECS 203-872-2,MFCD00002882,EPA Pesticide Chemical Code 338200,BRN 0969209,CHEBI:46807,AI3-08416,UNII-61BR964293,2,2'-Oxybis[Ethanol],Diethylene Glycol (DEG),NSC-36391,bis-(2-hydroxyethyl)ether,2,2-Di(hydroxyethyl) ether,DTXCID20462,DIETHYLENE GLYCOL ETHER,Bis(.beta.-hydroxyethyl) ether,61BR964293,EC 203-872-2,2,2-OXYDI(ETHAN-1-OL),4-01-00-02390 (Beilstein Handbook Reference),.beta.,.beta.'-Dihydroxydiethyl ether,2,2'-oxybis(ethanol),PEG 400,105400-04-2,149626-00-6,Diethylenglykol [Czech],DIETHYLENE GLYCOL (USP-RS),DIETHYLENE GLYCOL [USP-RS],diethylene-glycol,1,4,10,13-Tetraoxa-7,16-diazacyclooctadecane, 7,16-bis(1-oxodecyl)-,CAS-111-46-6,Chromate(2-), 2-5-(2,5-dichlorophenyl)azo-2-(hydroxy-.kappa.O)phenylmethyleneamino-.kappa.Nbenzoato(,GLYCEROL IMPURITY A (EP IMPURITY),GLYCEROL IMPURITY A [EP IMPURITY],PEG 200,PEG 600,OH-PEG2-OH,diehyleneglycol,Diglykol,Diethyleneglykol,diethyene glycol,2,2'-Oxydiethanol; Etofenamate Imp. F (EP); Etofenamate Impurity F; Glycerol Impurity A,di-ethylene glycol,PEG2000,Diethyl ene glycol,Glicole dietilenico,2-hydroxyethylether,1KA,Diethylenglykol rein,Ethanol,2'-oxydi-,2,2'-Ossidietanolo,2,2'-Oxibesethanol,Ethanol,2'-oxybis-,Glycol hydroxyethyl ether,Diethylene glycol, 99%,3-Oxypentane-1,5-diol,2,2-OXYBISETHANOL,SCHEMBL1462,HO(CH2CH2O)2H,2,2-Oxybis(ethan-1-ol),WLN: Q2O2Q,2-HYDROXYETHOXYETHANOL,MLS001055330,BIDD:ER0301,DIETHYLENE GLYCOL [MI],2-(2-Hydroxy-ethoxy)-ethanol,PEG600,CHEMBL1235226,DIETHYLENE GLYCOL [HSDB],HO(CH2)2O(CH2)2OH,2-(2-hydroxyethoxyl)ethan-1-ol,PEG4000,PEG6000,Diethylene glycol, LR, >=99%,3-OXA-1, 5-PENTANEDIOL,HMS2270G18,NSC32855,NSC32856,NSC35744,NSC35745,NSC35746,NSC36391,PEG35000,Tox21_201616,Tox21_300064,.beta.,.beta.'-Dihydroxyethyl ether,NSC-32855,NSC-32856,NSC-35744,NSC-35745,NSC-35746,STL280303,Diethylene glycol, analytical standard,AKOS000120101,1ST9049,FS-3891,PEG 10,000,PEG 20,000,NCGC00090703-01,NCGC00090703-02,NCGC00090703-03,NCGC00253996-01,NCGC00259165-01,2,2'-Oxydiethanol, 2-Hydroxyethyl ether,BP-20527,BP-22990,BP-23304,BP-25804,BP-25805,BP-31029,BP-31030,BP-31245,Diethylene glycol, ReagentPlus(R), 99%,SMR000112132,DB-092325,CS-0014055,D0495,ETOFENAMATE IMPURITY F [EP IMPURITY],NS00004483,EN300-19318,Diethylene glycol, BioUltra, >=99.0% (GC),Diethylene glycol, SAJ first grade, >=98.0%,E83357,A802367,Diethylene glycol, Vetec(TM) reagent grade, 98%,Q421902,J-002580,F1908-0125,9BAE4479-A6DD-4206-83C1-AB625AB87665,Diethylene glycol, puriss. p.a., >=99.0% (GC),colorless,InChI=1/C4H10O3/c5-1-3-7-4-2-6/h5-6H,1-4H,Diethylene glycol, United States Pharmacopeia (USP) Reference Standard,162662-01-3,31290-76-3,9002-90-8




Ethylene Glycol Dihydroxy Dimethyl Ether appears as a colorless liquid.
Ethylene Glycol Dihydroxy Dimethyl Ether is Denser than water.
Ethylene Glycol Dihydroxy Dimethyl Ether Contact may slightly irritate skin, eyes and mucous membranes.

Ethylene Glycol Dihydroxy Dimethyl Ether May be slightly toxic by ingestion.
Ethylene Glycol Dihydroxy Dimethyl Ether is Used to make other chemicals.
Ethylene Glycol Dihydroxy Dimethyl Ether is a hydroxyether.


APPLICATIONS OF ETHYLENE GLYCOL DIHYDROXY DIMETHYL ETHER
Ethylene Glycol Dihydroxy Dimethyl Ether may be used as a solvent to form a solution of sodium pentaphosphacyclopentadienide.


Ethylene Glycol Dihydroxy Dimethyl Ether is an organic compound with the formula (HOCH2CH2)2O.
Ethylene Glycol Dihydroxy Dimethyl Ether is a colorless, practically odorless, and hygroscopic liquid with a sweetish taste.
Ethylene Glycol Dihydroxy Dimethyl Ether is a four carbon dimer of ethylene glycol.


Ethylene Glycol Dihydroxy Dimethyl Ether is miscible in water, alcohol, ether, acetone, and ethylene glycol.[3]
Ethylene Glycol Dihydroxy Dimethyl Ether is a widely used solvent.[4]
Ethylene Glycol Dihydroxy Dimethyl Ether can be a normal ingredient in various consumer products, and it can be a contaminant.

Ethylene Glycol Dihydroxy Dimethyl Ether has also been misused to sweeten wine and beer, and to viscosify oral and topical pharmaceutical products.
Its use has resulted in many epidemics of poisoning since the early 20th century.[3]



PREPARATION OF ETHYLENE GLYCOL DIHYDROXY DIMETHYL ETHER:
Ethylene Glycol Dihydroxy Dimethyl Ether is produced by the partial hydrolysis of ethylene oxide.
Depending on the conditions, varying amounts of DEG and related glycols are produced.
The resulting product is two ethylene glycol molecules joined by an ether bond.[5]


"Diethylene glycol is derived as a co-product with ethylene glycol (MEG) and triethylene glycol.
The industry generally operates to maximize MEG production.
Ethylene Glycol Dihydroxy Dimethyl Ether is by far the largest volume of the glycol products in a variety of applications.

Availability of Ethylene Glycol Dihydroxy Dimethyl Ether will depend on demand for derivatives of the primary product, ethylene glycol, rather than on Ethylene Glycol Dihydroxy Dimethyl Ether market requirements."[6]

Structure of Ethylene Glycol Dihydroxy Dimethyl Ether and related polyols[edit]
Diethylene glycol is one of several glycols derived from ethylene oxide.

Glycols related to and co-produced with diethylene glycol and having the formula HOCH2CH2(OCH2CH2)nOH are:
n = 0 ethylene glycol ("antifreeze"); monoethylene glycol MEG
n = 1 DEG
n = 2 triethylene glycol, TEG, or triglycol
n = 3 tetraethylene glycol
n = 4 pentaethylene glycol
n > 4 polyethylene glycol
These compounds are all hydrophilic, more so than most diols, by virtue of the ether functionality.


USES OF ETHYLENE GLYCOL DIHYDROXY DIMETHYL ETHER:
Ethylene Glycol Dihydroxy Dimethyl Ether is used in the manufacture of saturated and unsaturated polyester resins, polyurethanes, and plasticizers.[6]
Ethylene Glycol Dihydroxy Dimethyl Ether is used as a building block in organic synthesis of, for example, morpholine and 1,4-dioxane.
Ethylene Glycol Dihydroxy Dimethyl Ether is a solvent for nitrocellulose, resins, dyes, oils, and other organic compounds.

Ethylene Glycol Dihydroxy Dimethyl Ether is a humectant for tobacco, cork, printing ink, and glue.[7]
Ethylene Glycol Dihydroxy Dimethyl Ether is also a component of brake fluid, lubricants, wallpaper strippers, artificial fog and haze solutions, and heating/cooking fuel.[3]

In personal care products (e.g. skin cream and lotions and deodorants), Ethylene Glycol Dihydroxy Dimethyl Ether is often replaced by selected diethylene glycol ethers.
A dilute solution of diethylene glycol can also be used as a cryoprotectant; however, ethylene glycol is much more commonly used.
Most types of ethylene glycol antifreeze contain a few percent of diethylene glycol, present as a by-product of ethylene glycol production.





CHEMICAL AND PHYSICAL PROPERTIES OF ETHYLENE GLYCOL DIHYDROXY DIMETHYL ETHER:
vapor density
4.6 (vs air)
Quality Level
100
vapor pressure
3 mmHg ( 20 °C)
product line
ReagentPlus®
Assay
99%
form
liquid
autoignition temp.
370 °F
expl. lim.
17.4 %
color
APHA: ≤10
refractive index
n20/D 1.408 (lit.)
pH
7 (20 °C)
bp
162 °C (lit.)
mp
−64 °C (lit.)
density
0.944 g/mL at 20 °C (lit.)
0.939 g/mL at 25 °C (lit.)

SMILES string
COCCOCCOC
InChI
1S/C6H14O3/c1-7-3-5-9-6-4-8-2/h3-6H2,1-2H3
InChI key
SBZXBUIDTXKZTM-UHFFFAOYSA-N
Chemical formula C4H10O3
Molar mass 106.12 g/mol
Appearance Colorless liquid
Density 1.118 g/mL
Melting point −10.45 °C (13.19 °F; 262.70 K)
Boiling point 244 to 245 °C (471 to 473 °F; 517 to 518 K)
Solubility in water miscible

Molecular Weight
106.12 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
XLogP3-AA
-1.3
Computed by XLogP3 3.0 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
2
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
3
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
4
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
106.062994177 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
106.062994177 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
49.7Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
7
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
26.1
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
0
Computed by PubChem
Undefined Atom Stereocenter Count
0
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
1
Computed by PubChem
Compound Is Canonicalized
Yes
Water <0.08%
Purity >99.5%
Acidity <0.015%
Appearance Clear colourless liquid
Peroxide <0.005%

Density 0.867 g/cm3 (20 °C)
Flash point 5°C
Ignition temperature 200 °C
Fusion point -58°C
pH value 7 (H₂O) neutral
Vapor pressure 66 hPa (20 °C)
Kinematic viscosity 0.455 mm2/s (25 °C)
Solubility 1000 g/l soluble





SAFETY INFORMATION ABOUT ETHYLENE GLYCOL DIHYDROXY DIMETHYL ETHER
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.



Ethylene Glycol Diacetate
cas no: 141-97-9 Acetoacetic ester; EAA; Ethyl beta-ketobutyrate; Acetoacetic ester, diacetic ether; Ethyl 3-oxobutanoate; Ethyl acetoacetate; Ethyl acetylacetate; 3-Oxobutanoic acid ethyl ester; Ethyl 3-ketobutyrate; Ethyl acetylacetate; Ethyl acetonecarboxylate; Ethylacetoacetat (German); Acetoacetato de metilo (Spanish); Acétoacétate de méthyle (French);
Ethylene Glycol Dimethacrylate
SYNONYMS Bromoethane; 1-Bromoethane; hydrobromic ether;Bromure D'ethyle; Ethane, Bromo-; Etylu Bromek (Polish); Monobromoethane; Cas no :74-96-4
Ethylene glycol distearate
Glycol Distearate; Ethylene Glycol Dioctadecanoate; Octadecanoic Acid, 1,2-Ethanediyl Ester; Ethylene Dioctadecanoate; 1,2-Ethanediyl Octadecanoate CAS NO: 627-83-8
ETHYLENE GLYCOL MONOBUTYL ETHER
Ethylene glycol monobutyl ether, also known as 2-Butoxyethanol, is an organic compound with an ether-like odor which comes from the family of glycol ethers.
Ethylene glycol monobutyl ether is a primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a butoxy group.
Ethylene glycol monobutyl ether belongs to the class of organic compounds known as dialkyl ethers.


CAS Number: 111-76-2
EC Number: 203-905-0
Chemical formula: C6H14O2


Ethylene glycol monobutyl ether appears as a colorless liquid with a mild, pleasant odor.
Ethylene glycol monobutyl ether is less dense than water.
The flash point of Ethylene glycol monobutyl ether is 160 °F.


Ethylene glycol monobutyl ether is a primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a butoxy group.
Ethylene glycol monobutyl ether has a role as a protic solvent.
Ethylene glycol monobutyl ether is a primary alcohol and a glycol ether.


Ethylene glycol monobutyl ether is a natural product found in Solanum tuberosum, Bidens pilosa, and other organisms with data available.
Ethylene glycol monobutyl ether is a colorless liquid with a mild odor that is used as a solvent in resins, varnishes and lacquers.
Ethylene glycol monobutyl ether is a primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a butoxy group.


Ethylene glycol monobutyl ether belongs to the class of organic compounds known as dialkyl ethers.
These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are alkyl groups.
Ethylene glycol monobutyl ether is versatile solvent of product obtains by reaction betweeen ethylene oxide and n-Butanol.


Ethylene glycol monobutyl ether is chemically known as a Butyl Glycol, 1-n-Butoxy-2-hydroxyethane, n-butyl (2-hydroxyethyl) ether.
Commercially Ethylene glycol monobutyl ether is known as a Butyl Cellosolve.
Ethylene glycol monobutyl ether is soluble in water, acetone, benzene, ethyl ether, methanol, carbon tetrachloride and other organic solvents and mineral oil.


Ethylene glycol monobutyl ether, also known as 2-Butoxyethanol or butyl cellosolve, is an organic compound with an ether-like odor which comes from the family of glycol ethers.
Ethylene glycol monobutyl ether, also known as ethylene glycol monobutyl ether, is a clear liquid with an ether-like odour.


Ethylene glycol monobutyl ether is a colorless and transparent liquid.
Ethylene glycol monobutyl ether (also called EGMBE and 2-Butoxyethanol) is a colourless, clear liquid with a sweet odour.
Ethylene glycol monobutyl ether is a mutual solvent, and is soluble in both oil and water.


Ethylene glycol monobutyl ether (also known as BG, 2-butoxyethanol, glycol monobutyl ether and butyl cellosolve, butoxyethanol) is a clear, colourless, oily liquid with a unique sweet yet mild odour and has the formula C6H14O2.
Ethylene glycol monobutyl ether is a butyl ether of ethylene glycol and is miscible with water and common organic solvents.


Since Ethylene glycol monobutyl ether dries lacquer coatings very slowly, it is ideal for the preparation of brushing lacquers based on cellulose esters, cellulose ethers and chlorinated rubber.
Even quite small additions of Ethylene glycol monobutyl ether to alkyd, the viscosity of the lacquer solution considerably reduce, thereby improving the brush-out property of such lacquers.


2-Butoxy Ethanol is a good intermediate solvent for use in mineral oil emulsion.
Even small quantities of Ethylene glycol monobutyl ether can disperse and stabilize such emulsion quite effectively.
Ethylene glycol monobutyl ether is versatile solvent of product obtains by reaction betweeen ethylene oxide and n-Butanol.


Ethylene glycol monobutyl ether is chemically known as a Butyl Glycol, 1-n-Butoxy-2-hydroxyethane, n-butyl (2-hydroxyethyl) ether.
Ethylene glycol monobutyl ether, also known as 2-Butoxyethanol or butyl cellosolve, is an organic compound with an ether-like odor which comes from the family of glycol ethers.


In 2006, the European production of butyl glycol ethers amounted to 181 kilotons, of which approximately 50% (90 kt/a) was Ethylene glycol monobutyl ether.
World production is estimated to be 200 to 500 kt/a, of which 75% is for paints and coatings and 18% for metal cleaners and household cleaners.
In the US, Ethylene glycol monobutyl ether is considered a high production volume chemical because more than 100 million pounds of this chemical are produced per year.


Ethylene glycol monobutyl ether is an organic compound with the chemical formula BuOC2H4OH (Bu = CH3CH2CH2CH2).
This colorless liquid, Ethylene glycol monobutyl ether, has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol.



USES and APPLICATIONS of ETHYLENE GLYCOL MONOBUTYL ETHER:
Ethylene glycol monobutyl ether is used Aerosol coatings, Aerospace coatings, Architectural coatings, Auto OEM, Auto refinish, Coil coatings, Commerical printing inks, Construction chemicals, Fabric care, Formulators, Furniture, Graphic arts, and Hard surface care.
Ethylene glycol monobutyl ether is used Industrial cleaners, Institutional cleaners, Janitorial & household cleaners, Lubricants, Marine, Oil or gas processing, Paints & coatings, Process solvents, Protective coatings, Rubber modification, Soap/detergents, and Wood coatings.


Ethylene glycol monobutyl ether is also used as an ingredient in paint thinners, herbicides, household products and cosmetics.
A high-boiling (171degreeC) colourless liquid, Ethylene glycol monobutyl ether is used as a solvent for paints and inks, as well as in some dry cleaning solutions.


Ethylene glycol monobutyl ether is mainly used as a high boiling point solvent for paints, especially nitro spray paints, fast drying paints, varnishes, enamels and paint strippers.
Ethylene glycol monobutyl ether is also used as an inactive diluent for adhesives.


Ethylene glycol monobutyl ether is used Metal detergent, Paint stripper, Fiber wetting agent, Pesticide dispersants, Drug extractants, and Resin plasticizers.
Ethylene glycol monobutyl ether is a colorless liquid with a mild odor that is used as a solvent in resins, varnishes and lacquers.


Other applications of Ethylene glycol monobutyl ether include use as a solvent in printing inks due to its high boiling point, textile dyes and as a component of hydraulic fluids.
Ethylene glycol monobutyl ether is also a component of drilling and cutting oils and is a major component of Corexit 9527, which is an oil spill dispersant product.


Ethylene glycol monobutyl ether is also a chemical intermediate and, as such, is a starting material in the production of butyl glycol acetate which is, itself, an excellent solvent.
Ethylene glycol monobutyl ether is also a starting material in the production of plasticisers by the reaction of phthalic anhydride.


Ethylene glycol monobutyl ether sees use in various industries due to solvent and surfactant properties.
Ethylene glycol monobutyl ether sees extensive use in oil and gas and energy industries as well as household and industrial cleaning products, as well as surface coatings.


Ethylene glycol monobutyl ether has been produced industrially for over half a century and is used primarily as a solvent in paints and surface coatings but also in inks and cleaning products.
Ethylene glycol monobutyl ether has many uses, primarily as a solvent, in both the commercial and industrial industries.


Many other products contain Ethylene glycol monobutyl ether including spray lacquers, varnishes, varnish removers, paints, liquid soaps, degreasers, leather protectors, whiteboard cleaners, printing pastes, enamels, cosmetics and herbicides.
Ethylene glycol monobutyl ether acts as a plasticizer and solvent.


Ethylene glycol monobutyl ether enhances the deformability of polymeric compounds.
Ethylene glycol monobutyl ether is compatible with nitrocellulose and synthetic resins.
Ethylene glycol monobutyl ether is used in plastics.


Ethylene glycol monobutyl ether can be used as a solvent in paint and as a solvent in enamel paint remover.
Ethylene glycol monobutyl ether is a solvent that can also be found in kitchen and all-purpose cleaners.
Ethylene glycol monobutyl ether is used to dissolve oils and grease.


Ethylene glycol monobutyl ether is used as a solvent and to make paints and varnish.
A high-boiling (171℃) colourless liquid, Ethylene glycol monobutyl ether is used as a solvent for paints and inks, as well as in some dry cleaning solutions.


Ethylene glycol monobutyl ether offers numerous benefits in coating, ink, and cleaner applications.
Ethylene glycol monobutyl ether is an excellent solvent for many coatings resin types, including alkyd, phenolic, maleic, epoxy, and nitrocellulose resins.
Ethylene glycol monobutyl ether is an exceptional retarder solvent for lacquers, improving gloss and flow-out.


Ethylene glycol monobutyl ether is also widely used in amine-solubilized, water-based coatings because of its high flash point, complete water solubility, slow evaporation rate, low surface tension, and high coupling efficiency.
Ethylene glycol monobutyl ether is an effective coalescent that improves film integrity in both architectural and industrial maintenance latex paints.


Ethylene glycol monobutyl ether's unique combination of properties enables the effective removal of contaminants when used in Industrial & Institutional and/or household cleaners.
Ethylene glycol monobutyl ether is used component of cleaning products, cosmetics, lacquers, latex paint, firefighting foam, hydraulic fluid.


Ethylene glycol monobutyl ether is employed primarily in the production of lacquers based on nitrocellulose, cellulose ethers and chlorinated rubber.
Small quantities of Ethylene glycol monobutyl ether are also used combination lacquers.
Solutions of nitrocellulose in Ethylene glycol monobutyl ether may be diluted with large quantity of white spirit, aromatic hydrocarbons or ethanol without adversely affecting the film property.


Small quantities of Ethylene glycol monobutyl ether improves both the flow and dilution capacity of the lacquers and also enhance the gloss of the resultant lacquer films.
As a relatively nonvolatile, inexpensive solvent, Ethylene glycol monobutyl ether is used in many domestic and industrial products because of its properties as a surfactant.
Ethylene glycol monobutyl ether is a glycol ether with modest surfactant properties, which can also be used as a mutual solvent.


-Industry Uses:
Ethylene glycol monobutyl ether usage is dominated by the paint industry which consumes approximately 75 % of all the BG produced.
This is because Ethylene glycol monobutyl ether is a low volatility solvent and can therefore both extend the drying times of coatings and improve their flow.


-Commercial Uses:
Ethylene glycol monobutyl ether is used regularly in most households as it is a component of many home cleaning products.
Ethylene glycol monobutyl ether provides excellent cleaning power for domestic cleaning products and also provides the characteristic odour that we associate with them.
Ethylene glycol monobutyl ether also plays the same role in some industrial and commercial surface cleaners.


-Commercial uses:
Ethylene glycol monobutyl ether is a solvent for paints and surface coatings, as well as cleaning products and inks.
Products that contain Ethylene glycol monobutyl etherinclude acrylic resin formulations, asphalt release agents, firefighting foam, leather protectors, oil spill dispersants, degreaser applications, photographic strip solutions, whiteboard and glass cleaners, liquid soaps, cosmetics, dry cleaning solutions, lacquers, varnishes, herbicides, latex paints, enamels, printing paste, and varnish removers, and silicone caulk.

Products containing Ethylene glycol monobutyl ether are commonly found at construction sites, automobile repair shops, print shops, and facilities that produce sterilizing and cleaning products.
Ethylene glycol monobutyl ether is the main ingredient of many home, commercial and industrial cleaning solutions.

Since the molecule has both polar and non-polar ends, Ethylene glycol monobutyl ether is useful for removing both polar and non-polar substances, like grease and oils.
Ethylene glycol monobutyl ether is also approved by the U.S. FDA to be used as direct and indirect food additives, which include antimicrobial agents, defoamers, stabilizers, and adhesives.


-In the petroleum industry:
Ethylene glycol monobutyl ether is commonly produced for the oil industry because of its surfactant properties.
In the petroleum industry, Ethylene glycol monobutyl ether is a component of fracturing fluids, drilling stabilizers, and oil slick dispersants for both water-based and oil-based hydraulic fracturing.

When liquid is pumped into the well, the fracturing fluids are pumped under extreme pressure, so Ethylene glycol monobutyl ether is used to stabilize them by lowering the surface tension.
As a surfactant, Ethylene glycol monobutyl ether absorbs at the oil-water interface of the fracture.
Ethylene glycol monobutyl ether is also used to facilitate the release of the gas by preventing congealing.

Ethylene glycol monobutyl ether is also used as a crude oil–water coupling solvent for more general oil well workovers.
Because of its surfactant properties, Ethylene glycol monobutyl ether is a major constituent (30–60% w/w) in the oil spill dispersant Corexit 9527, which was widely used in the aftermath of the 2010 Deepwater Horizon oil spill.



HOW IS ETHYLENE GLYCOL MONOBUTYL ETHER PRODUCED?
Ethylene glycol monobutyl ether is produced by reacting ethylene oxide with an alcohol such as normal butanol (nbutanol) within a catalyst.
This process is called ethoxylation.
If the ratio of ethylene oxide to nbutanol is greater than one then di- and tri- ethylene glycol monoethers are also produced.
Below is the chemical equation for this reaction:
C2H4O + C4H9OH → C4H9OC2H4OH
World production is estimated at between 300-500 KT per annum. Ethylene glycol monobutyl ether can also be produced through the etherification of butanol with 2-chloroethanol.



WHERE IS ETHYLENE GLYCOL MONOBUTYL ETHER FOUND AND HOW IS ETHYLENE GLYCOL MONOBUTYL ETHER USED?
Ethylene glycol monobutyl ether itself is not commercially produced in Canada.
Ethylene glycol monobutyl ether is widely used in a range of commercial and consumer products, such as paints, cleaning products and solvents, as well as in some industrial applications.



PRODUCTION OF ETHYLENE GLYCOL MONOBUTYL ETHER:
Ethylene glycol monobutyl ether is commonly obtained through two processes; the ethoxylation reaction of butanol and ethylene oxide in the presence of a catalyst:

C2H4O + C4H9OH → C4H9OC2H4OH
or the etherification of butanol with 2-chloroethanol.
Ethylene glycol monobutyl ether can be obtained in the laboratory by performing a ring opening of 2-propyl-1,3-dioxolane with boron trichloride.
Ethylene glycol monobutyl ether is often produced industrially by combining ethylene glycol and butyraldehyde in a Parr reactor with palladium on carbon.



KEY ATTRIBUTES OF ETHYLENE GLYCOL MONOBUTYL ETHER:
*Efficient coalescent
*Excellent coupling efficiency
*Good solvent activity
*High blush resistance
*Inert - Food use with limitations
*Inert - Nonfood use
*Low surface tension
*Miscible with water and most organic liquids
*Non-HAP
*REACH compliant
*Readily biodegradable
*Slow evaporation rate



ALTERNATIVE PARENTS OF ETHYLENE GLYCOL MONOBUTYL ETHER:
*Primary alcohols
*Hydrocarbon derivatives



SUBSTITUENTS OF ETHYLENE GLYCOL MONOBUTYL ETHER:
*Dialkyl ether
*Hydrocarbon derivative
*Primary alcohol
*Alcohol
*Aliphatic acyclic compound



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENE GLYCOL MONOBUTYL ETHER:
Chemical formula: C6H14O2
Molar mass: 118.176 g·mol−1
Appearance: Clear, colorless liquid
Density: 0.90 g/cm3, liquid
Melting point: −77 °C (−107 °F; 196 K)
Boiling point: 171 °C (340 °F; 444 K)
Solubility in water: Miscible (and in most organic solvents)
Vapor pressure: 0.8 mmHg
Acidity (pKa): High pKa for −OH group
Refractive index (nD): 1.4198 (20 °C)
Viscosity: 2.9 cP at 25 °C (77 °F)
Dipole moment: 2.08 D
Flash point: 67 °C (153 °F; 340 K)
Autoignition temperature: 245 °C (473 °F; 518 K)
Explosive limits: 1.1–12.7%

Molecular Weight: 118.17 g/mol
XLogP3: 0.8
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 5
Exact Mass: 118.099379685 g/mol
Monoisotopic Mass: 118.099379685 g/mol
Topological Polar Surface Area: 29.5Ų
Heavy Atom Count: 8
Formal Charge: 0
Complexity: 37.5
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1

Compound Is Canonicalized: Yes
CAS number: 111-76-2
EC index number: 603-014-00-0
EC number: 203-905-0
Hill Formula: C₆H₁₄O₂
Chemical formula: C₄H₉OCH₂CH₂OH
Molar Mass: 118.18 g/mol
HS Code: 2909 43 00
Density: 0.90 g/cm3 (20 °C)
Explosion limit: 1.1 - 10.6 %(V)
Flash point: 67 °C
Melting Point: -75 °C
pH value: 7 (H₂O, 20 °C) (as aqueous solution)
Vapor pressure: 0.8 hPa (20 °C)
Viscosity kinematic: 3.642 mm2/s (20 °C)
Solubility: 900 g/l soluble
Density: 0.90 g/cm3 (20 °C)
Explosion limit: 1.1 - 10.6 %(V)

Flash point: 67 °C
Melting Point: -75 °C
pH value: 7 (H₂O, 20 °C) (as aqueous solution)
Vapor pressure: 0.8 hPa (20 °C)
Viscosity kinematic: 3.642 mm2/s (20 °C)
Solubility: 900 g/l soluble
Physical state: liquid
Color: colorless
Odor: ether-like, mild, sweet
Melting point/freezing point:
Melting point/range: -75 °C
Initial boiling point and boiling range: 173,5 °C at 1.013 hPa - (ECHA)
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 12,7 %(V)
Lower explosion limit: 1,1 %(V)
Flash point: 67 °C
Autoignition temperature: 230 °C
at 1.013,25 hPa - DIN 51794

Decomposition temperature: Distillable in an undecomposed state at normal pressure.
pH 7 at 20 °C (as aqueous solution)
Viscosity
Viscosity, kinematic: 3,642 mm2/s at 20 °C2,284 mm2/s at 40 °C
Viscosity, dynamic: 3,6 mPa.s at 20 °C
Water solubility: No data available
Partition coefficient: n-octanol/water: log Pow: 0,81 at 25 °C
Vapor pressure: No data available
Density: 0,90 g/cm3 at 20 °C - DIN 51757
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Surface tension: 65,03 mN/m at 2g/l at 20 °C
Relative vapor density: 4,08 - (Air = 1.0)

Formula: C6H14O2
Formula mass: 118.18
Melting point, °C: -70
Boiling point, °C: 171
Vapor pressure, mmHg: 0.8 (20 C)
Vapor density (air=1): 4.1
Saturation Concentration: 0.1% at 20 C
Evaporization number: 0.07 (butyl acetate = 1)
Critical temperature: 370
Critical pressure: 38.50
Density: 0.902 g/cm3 (20 C)
Solubility in water: Miscible
Viscosity: 1.87 cp (40 C)
Surface tension: 27.4 g/s2 @ 25 C.
Refractive index: 1.4196 (20 C)
Dipole moment: 1.8 D
Dielectric constant: 9.4 (20 C)
Partition coefficient, pKow: 0.83

Heat of vaporization: 47.1 kJ/mol
Heat of combustion: -4163 kJ/mol
Boiling Range: 2°C max.
Melting Point: -70°C
Color: Yellow
Density: 0.901g/cm³
Boiling Point: 171°C
Linear Formula: HOCH2CH2O(CH2)3CH3
UN Number: 2810
Refractive Index: 1.418 to 1.420 (at 20°C)
Formula Weight: 118.18
Vapor Pressure: 0.8 hPa at 20°C
Physical Form: Liquid
Chemical Name or Material: Ethylene Glycol Monobutyl Ether

Cas Number: 111-76-2
Molecular Mass: 118.176 g/mol1
Exact Mass: 118.09938 g/mol
Flashpoint: 153 °F / 67 °C
Boiling Point: 340 °F / 171 °C
Melting Point: -107 °F / -77 °C
Vapour Pressure: 0.76 mm Hg at 68 ° F
Water Solubility: ≥ 100 mg/ml (72° F)
Density: 0.90 g/cm3
Log P: 0.83
Chemical Formula: C6H14O2
Average Molecular Mass: 118.174 g/mol
Monoisotopic Mass: 118.099 g/mol
CAS Registry Number: 111-76-2
IUPAC Name: 2-butoxyethan-1-ol
Traditional Name: butoxyethanol
SMILES: CCCCOCCO
InChI Identifier: InChI=1S/C6H14O2/c1-2-3-5-8-6-4-7/h7H,2-6H2,1H3
InChI Key: POAOYUHQDCAZBD-UHFFFAOYSA-N

Water Solubility: 76.5 g/L
logP: 0.78
logP: 0.76
logS: -0.19
pKa (Strongest Acidic): 15.12
pKa (Strongest Basic): -2.7
Physiological Charge: 0
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 1
Polar Surface Area: 29.46 Ų
Rotatable Bond Count: 5
Refractivity: 33.18 m³·mol⁻¹
Polarizability: 14.37 ų
Number of Rings: 0
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: Yes
MDDR-like Rule: No



FIRST AID MEASURES of ETHYLENE GLYCOL MONOBUTYL ETHER:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Call a physician immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ETHYLENE GLYCOL MONOBUTYL ETHER:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ETHYLENE GLYCOL MONOBUTYL ETHER:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENE GLYCOL MONOBUTYL ETHER:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 120 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A (acc. to DIN 3181)
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ETHYLENE GLYCOL MONOBUTYL ETHER:
-Precautions for safe handling
*Advice on safe handling
Work under hood.
*Advice on protection against fire and explosion
Take precautionary measures against static discharge.
*Hygiene measures
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities
*Storage conditions
Do not use light-weight-metal containers.
Protected from light.
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Recommended storage temperature see product label.



STABILITY and REACTIVITY of ETHYLENE GLYCOL MONOBUTYL ETHER:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available



SYNONYMS:
2-Butoxyethanol
111-76-2
ETHYLENE GLYCOL MONOBUTYL ETHER
Butyl glycol
Butyl cellosolve
Butoxyethanol
n-Butoxyethanol
Ethanol, 2-butoxy-
Ethylene glycol butyl ether
Butyl oxitol
Dowanol EB
Glycol butyl ether
Glycol ether eb
3-Oxa-1-heptanol
2-butoxyethan-1-ol
EGBE
2-Butoxy-1-ethanol
Gafcol EB
2-n-Butoxyethanol
O-Butyl ethylene glycol
Jeffersol eb
Butyl cellu-sol
BUCS
Ektasolve EB
Glycol monobutyl ether
Chimec NR
2-Butoxy ethanol
2-Butossi-etanolo
2-Butoxy-aethanol
Butylcelosolv
Butylglycol
Butoksyetylowy alkohol
2-Butoxy-ethanol
Ethylene glycol n-butyl ether
EGMBE
Monobutyl glycol ether
Monobutyl ether of ethylene glycol
Ethylene glycol mono-n-butyl ether
n-Butyl Cellosolve
.beta.-Butoxyethanol
9004-77-7
Butyl monoether glycol
Caswell No. 121
Butyglycol
Monobutyl ethylene glycol ether
2-n-Butoxy-1-ethanol
Ether alcohol
Ethylene glycol, monobutyl ether
Butyl icinol
g lycol ether eb
beta-Butoxyethanol
2 -Butoxyethanol
Minex BDH
2-Hydroxyethyl n-butyl ether
Butoxyethanol, 2-
ethyleneglycol monobutyl ether
Ektasolve EB solvent
CCRIS 5985
HSDB 538
2-Butoxyethanol (ethylene glycol monobutyl ether)
2-Butoxyethan(ol-d)
2-Butoxyethanol--d4
Ek tasolve EB solvent
Eter monobutilico del etilenglicol
Glycol ether eb acetate
EINECS 203-905-0
UNII-I0P9XEZ9WV
UN2369
I0P9XEZ9WV
Butyl 2-hydroxyethyl ether
EPA Pesticide Chemical Code 011501
BRN 1732511
AI3-0993
AI3-09903
NSC-60759
2-BUTOXY(ETHANOL-13C2)
EC 203-905-0
EC 500-012-0
Ethylene glycol monobutyl ether (EGBE)(2-Butoxyet)
DTXCID904097
2-BUTOXY ETHANOL (ETHYLENE GLYCOL MONOBUTYL ETHER)
butylcellosolve
CAS-111-76-2
SMR001253761
n-butoxyethanol sodium salt
Butyloxitol
2-Butoksyetanol
2-Butoxietanol
EB Solvent
2- butoxyethanol
3-oxaheptan-1-ol
Etanol, 2-butoxi-
2-(n-Butoxy)ethanol
BuOCH2CH2OH
EGM (CHRIS Code)
Ethylene glycol monobutyl
2-Butoxyethanol (EGBE)
2-(1-Butyloxy) ethanol
Aethylenglycolmonobuthylaether
BUTOXYETHANOL [INCI]
2-Butoxy-aethanol(GERMAN)
SCHEMBL15712
Ethyleneglycol-monobutyl ether
MLS002174253
MLS002454362
WLN: Q2O4
BUTYL CELLOSOLVE [MI]
ethylene glycol-monobutyl ether
CHEMBL284588
QSPL 003
2-BUTOXYETHANOL [IARC]
2-BUTOXYETHANOL [VANDF]
Ethylene glycol butyl ether, 99%
2-butoxyethanol (butyl cellosolve)
NSC60759
(C2-H4-O)mult-C4-H10-O
ther d'thylneglycol et de monobutyle
Tox21_202399
Tox21_300123
LS-539
MFCD00002884
NA2369
Ethylene glycol butyl ether, >=99%
AKOS009028760
Ethylene glycol monobutyl ether (EGBE)
NCGC00090683-01
NCGC00090683-02
NCGC00090683-03
NCGC00090683-04
NCGC00090683-05
NCGC00254083-01
NCGC00259948-01
Ethylene glycol monobutyl ether (EGBE)
B0698
FT-0626297
UVCB substance. IUPAC name not applicable.
EN300-19317
C19355
500-012-0 (NLP #)
Ethylene glycol butyl ether, analytical standard
ETHYLENE GLYCOL MONO-N-BUTYL ETHER [HSDB]
Q421557
Ethylene glycol butyl ether, for synthesis, 99.0%
J-508565
Butoxyethanol, 2-
(Glycol ether EB; Xtraction II)
Butoxyethanol, 2-
(Glycol ether EB; Xtraction II)
Ethylene glycol butyl ether, SAJ first grade, >=99.0%
Ethylene glycol monobutyl ether (EGBE) (2-Butoxyethanol)
Ethylene glycol butyl ether, spectrophotometric grade, >=99.0%
Ethylene glycol monobutyl ether [UN2369]
Ethylene glycol monobutyl ether [UN2369]
EGBE, AI-0993
Bucs
Butoxyethanol
Beta-butoxyethanol
2-Butoxyethanol
2-butoxy-1-ethanol
Butyl cellosolve
o-butyl ethylene glycol
Butyl glycol
Butyl oxitol
Caswell No. 121
Ethylne glycol butyl ether
Ethylene glycol monobutyl ether
Glycol butyl ether
Monobutyl glycol ether
3-oxa-1-heptanol
EPA Pesticide Code: 011501
2-Butoxyethanol
Butyl Cellosolve
Butyl Monoether Glycol
Ethylene Glycol Monobutyl Ether (EGBE)
Butoxyethanol
2-Butoxyethanol
Butyl Cellosolve
n-Butyl Glycol
Butyl Glycol
2‐n‐Butoxyethanol
2-Butoxyethyl acetate
Butyl Cellosolve acetate
Butyl glycol acetate
EGBEA
Ektasolve EB acetate
Ethylene glycol monobutyl ether acetate
2-Hydroxyethyl N-butyl ether
3-Oxa-1-heptanol
BuOCH2ch2oh
Butoxyethanol
Butyl cellosolve
Butyl glycol
Butyl oxitol
Ethylene glycol butyl ether
Ethylene glycol mono-N-butyl ether
Ethylene glycol monobutyl ether
Glycol butyl ether
N-Butoxyethanol ChEBI
O-Butyl ethylene glycol
2-Butossi-etanolo
2-Butoxy ethanol
2-BUTOXY ethanol (ethylene glycol monobutyl ether)
2-Butoxy-1-ethanol
2-Butoxy-aethanol
2-Butoxy-ethanol
2-Butoxyethan-1-ol
2-Butoxyethanol (butyl cellosolve)
2-Butoxyethanol (ethylene glycol monobutyl ether)
2-N-Butoxy-1-ethanol
2-N-Butoxyethanol
beta-Butoxyethanol
BUCS
Butoksyetylowy alkohol
Butyglycol
Butyl 2-hydroxyethyl ether
Butyl cellu-sol
Butyl icinol
Butyl monoether glycol
Butylcellosolve
Butylcelosolv
Butylglycol
Butyloxitol
Chimec NR
Dowanol eb
Eb solvent
EGBE
Egmbe
Eter monobutilico del etilenglicol
Ether alcohol
Ethylene glycol mono butyl ether
Ethylene glycol monobutyl ether (egbe)(2-butoxyet)
Ethylene glycol N-butyl ether
Ethylene glycol, monobutyl ether
Ethyleneglycol monobutyl ether
Gafcol eb
Glycol monobutyl ether
Minex BDH
Monobutyl ether OF ethylene glycol
Monobutyl ethylene glycol ether
Monobutyl glycol ether
N-Butoxyethanol sodium salt
N-Butyl cellosolve
Poly-solv eb
2-Butoxyethanol,2-(1-butoxy)ethanol,2-be
2-Butossi-etanolo
2-Butoxy-1-ethanol·2-Butoxy-aethanol
2-Butoxyethan-1-ol
2-butoxy-ethano
2-butoxyethanol (butyl cellosolve)




ETHYLENE GLYCOL MONOBUTYL ETHER
DESCRIPTION:

Ethylene glycol monobutyl ether is a primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a butoxy group.
Ethylene glycol monobutyl ether has a high-boiling (171℃) colourless liquid.
Ethylene glycol monobutyl ether is used as a solvent for paints and inks, as well as in some dry cleaning solutions.



CAS NUMBER: 111-76-2

MOLECULAR FORMULA: CH3(CH2)2CH2OCH2CH2OH

MOLECULAR WEIGHT: 118.17




DESCRIPTION:

Ethylene glycol monobutyl ether has a role as a protic solvent.
Ethylene glycol monobutyl ether is a primary alcohol and a glycol ether.
Ethylene glycol monobutyl ether is a natural product.
Ethylene glycol monobutyl ether appears as a colorless liquid with a mild, pleasant odor.

Ethylene glycol monobutyl ether is a colorless liquid with a mild, pleasant odor.
Ethylene glycol monobutyl ether has less dense than water.
Ethylene glycol monobutyl ether's flash point is 160°F.
Ethylene glycol monobutyl ether irritates skin and eyes.

Ethylene glycol monobutyl ether is used as a solvent and to make paints and varnish.
Ethylene glycol monobutyl ether is an organic compound with the chemical formula BuOC2H4OH (Bu = CH3CH2CH2CH2).
This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol.
As a relatively nonvolatile, inexpensive solvent, it is used in many domestic and industrial products because of its properties as a surfactant.

Ethylene glycol monobutyl ether can be obtained in the laboratory by performing a ring opening of 2-propyl-1,3-dioxolane with boron trichloride.
Ethylene glycol monobutyl ether offers numerous benefits in coating, ink, and cleaner applications.
Ethylene glycol monobutyl ether is an excellent solvent for many coatings resin types, including alkyd, phenolic, maleic, epoxy, and nitrocellulose resins.
Ethylene glycol monobutyl ether is an exceptional retarder solvent for lacquers, improving gloss and flow-out.

Ethylene glycol monobutyl ether is also widely used in amine-solubilized, water-based coatings because of its high flash point, complete water solubility, slow evaporation rate, low surface tension, and high coupling efficiency.
Ethylene glycol monobutyl ether is an effective coalescent that improves film integrity in both architectural and industrial maintenance latex paints.
Ethylene glycol monobutyl ether's unique combination of properties enables the effective removal of contaminants when used in Industrial & Institutional and/or household cleaners.

Ethylene glycol monobutyl ether is a clear, colourless, oily liquid with a unique sweet yet mild odour and has the formula C6H14O2.
Ethylene glycol monobutyl ether is a butyl ether of ethylene glycol and is miscible with water and common organic solvents.
Ethylene glycol monobutyl ether has been produced industrially for over half a century and is used primarily as a solvent in paints and surface coatings but also in inks and cleaning products.



APPLICATION:

-Aerosol coatings
-Aerospace coatings
-Architectural coatings
-Auto OEM
-Auto refinish
-Coil coatings
-Commerical printing inks
-Construction chemicals
-Fabric care
-Formulators
-Furniture
-Graphic arts
-Hard surface care
-Industrial cleaners
-Institutional cleaners
-Janitorial & household cleaners
-Lubricants
-Marine
-Oil or gas processing
-Paints & coatings
-Process solvents
-Protective coatings
-Rubber modification
-Soap/detergents
-Wood coatings



BENEFITS:

-Efficient coalescent
-Excellent coupling efficiency
-Good solvent activity
-High blush resistance
-Inert - Food use with limitations
-Inert - Nonfood use
-Low surface tension
-Miscible with water and most organic liquids
-Non-HAP
-REACH compliant
-Readily biodegradable
-Slow evaporation rate



PROPERTIES:

-Melting Point: -75 °C
-Boiling Point: 171 °C
-Flash point: 68 °C
-Specific Gravity (20/20): 0.90
-Refractive Index: 1.42
-Solubility in water: Completely miscible
-Solubility (miscible with): Alcohol, Ether, Benzene, Heptane, Acetone



PHYSICAL PROPERTIES:

-Boiling Point °C: 171.2
-Melting Point °C: -70.0
-Specific Gravity 20/20°C: 0.902
-Flash Point (closed cup) °C: 67.5



PHYSICAL AND CHEMICAL PROPERTIES:

-Density: 0.90 g/cm3 (20 °C)
-Explosion limit: 1.1 - 10.6 %(V)
-Flash point: 67 °C
-Melting Point: -75 °C
-pH value: 7 (H₂O, 20 °C) (as aqueous solution)
-Vapor pressure: 0.8 hPa (20 °C)
-Viscosity kinematic: 3.642 mm2/s (20 °C)
-Solubility: 900 g/l soluble



PROPERTIES:

-Molecular Weight: 118.17
-XLogP3: 0.8
-Hydrogen Bond Donor Count: 1
-Hydrogen Bond Acceptor Count: 2
-Rotatable Bond Count: 5
-Exact Mass: 118.099379685
-Monoisotopic Mass: 118.099379685
-Topological Polar Surface Area: 29.5 Ų
-Heavy Atom Count: 8
-Complexity: 37.5
-Isotope Atom Count: 0
-Defined Atom Stereocenter Count: 0
-Undefined Atom Stereocenter Count: 0
-Defined Bond Stereocenter Count: 0
-Undefined Bond Stereocenter Count: 0
-Covalently-Bonded Unit Count: 1
-Compound Is Canonicalized: Yes



SPECIFICATION:

-Assay (GC, area%): ≥ 99.0 % (a/a)
-Density (d 20 °C/ 4 °C): 0.900 - 0.901
-Water (K. F.): ≤ 0.20 %
-Peroxide (as H₂O₂): ≤ 0.05 %
-Identity (IR): passes test



STORAGE:

Store below +30°C.



SYNONYM:

2-Butoxyethanol
111-76-2
ETHYLENE GLYCOL MONOBUTYL ETHER
Butyl glycol
Butyl cellosolve
Butoxyethanol
n-Butoxyethanol
Ethanol, 2-butoxy
Ethylene glycol butyl ether
Butyl oxitol
Dowanol EB
Glycol butyl ether
Glycol ether eb
3-Oxa-1-heptanol
2-butoxyethan-1-ol
EGBE
2-Butoxy-1-ethanol
Gafcol EB
2-n-Butoxyethanol
O-Butyl ethylene glycol
Jeffersol eb
Butyl cellu-sol
BUCS
Ektasolve EB
Glycol monobutyl ether
Chimec NR
2-Butoxy ethanol
2-Butossi-etanolo
2-Butoxy-aethanol
Butylcelosolv
Butylglycol
Butoksyetylowy alkohol
2-Butoxy-ethanol
Ethylene glycol n-butyl ether
EGMBE
Monobutyl glycol etherMonobutyl ether of ethylene glycol
Ethylene glycol mono-n-butyl ethern-Butyl Cellosolve
.beta.-Butoxyethanol
ethyleneglycol monobutyl ether
Butyl monoether glycol
Butyglycol
Monobutyl ethylene glycol ethe
2-n-Butoxy-1-ethanol
Ether alcohol
Ethylene glycol, monobutyl ether
Butyl icinol
Minex BDH
NSC 60759
2-Hydroxyethyl n-butyl ether
2-Butoxyethanol (ethylene glycol monobutyl ether)
9004-77-7
Eter monobutilico del etilenglicol
I0P9XEZ9WV
Butyl 2-hydroxyethyl ether
Ether monobutylique de l'ethyleneglycol
DTXSID1024097
CHEBI:63921
NSC-60759
DTXCID904097
butylcellosolve
g lycol ether eb
beta-Butoxyethanol
2 -Butoxyethanol
CAS-111-76-2
SMR001253761
Butoxyethanol, 2-
Ektasolve EB solvent
CCRIS 5985
HSDB 538
Ek tasolve EB solvent
Glycol ether eb acetate
EINECS 203-905-0
UNII-I0P9XEZ9WV
UN2369
n-butoxyethanol sodium salt
EPA Pesticide Chemical Code 011501
BRN 1732511
Butyloxitol
AI3-0993
butoxy-ethanol
AI3-09903
Ethylene glycol mono butyl ether
Butyl Glycolether
EB Solvent
3-oxaheptan-1-ol
2-(n-Butoxy)ethanol
BuOCH2CH2OH
2-(1-Butyloxy) ethanol
EC 203-905-0
EC 500-012-0
Aethylenglycolmonobuthylaether
BUTOXYETHANOL [INCI]
2-Butoxy-aethanol(GERMAN)
SCHEMBL15712MLS002174253
MLS002454362
WLN: Q2O4
BUTYL CELLOSOLVE
Butyglycol(FRENCH, GERMAN
Ethylene glycol monobutyl ether
ethylene glycol-monobutyl ether
CHEMBL284588
QSPL 003
2-BUTOXYETHANOL
2-BUTOXYETHANOL
2-BUTOXY ETHANOL (ETHYLENE GLYCOL MONOBUTYL ETHER)
Ethylene glycol butyl ether, 99%
2-butoxyethanol
NSC60759
ZINC1690437
Tox21_202399
Tox21_300123
MFCD00002884
Ethylene glycol butyl ether, >=99%
AKOS009028760
NCGC00090683-01
NCGC00090683-02
NCGC00090683-03
NCGC00090683-04
NCGC00090683-05
NCGC00254083-01
NCGC00259948-01
LS-13220
B0698
FT-0626297
EN300-19317
Ethylene Glycol Monobutyl Ether Reagent Grade
C19355
Ethylene glycol butyl ether, analytical standard
ETHYLENE GLYCOL MONO-N-BUTYL ETHER
Q421557
Ethylene glycol butyl ether, for synthesis, 99.0%
J-508565
Ethylene glycol butyl ether, SAJ first grade, >=99.0%
Ethylene glycol butyl ether, spectrophotometric grade, >=99.0%



































ETHYLENE GLYCOL MONOSTEARATE
cas no 111-60-4 Glycol Monostearate ; Octadecanoic Acid, 1,2-Ethanediyl Ester; Ethylene Octadecanoate; 1,2-Ethanediyl Octadecanoate; Ethylene Glycol Monooctadecanoate; 2-Hydroxyethyl stearate;
ETHYLENE GLYCOL N-HEXYL ETHER
Ethylene glycol n-hexyl ether is a colorless liquid with a slight ether odor and bitter taste.
Ethylene glycol n-hexyl ether has the characteristic structure of glycol ethers and contains both ether and alcohol functional groups in the same molecule.
Ethylene glycol n-hexyl ether is a clear, mobile, neutral, slightly hygroscopic liquid with a mild odor.


CAS number: 112-25-4
EC number: 203-951-1
MDL Number: MFCD00045997
Molecular formula: C8H18O2


Ethylene glycol n-hexyl ether is a solvent that can be found in a variety of rust removers, hard surface cleaners and disinfectants.
Ethylene glycol n-hexyl ether, as known 2-Hexoxyethanol or 2-(Hexyloxy)ethanol, is a glycol ether that has a chemical formula of C8H18O2.
Ethylene glycol n-hexyl ether is miscible with all common solvents, e. g. alcohols, ketones, aldehydes, ethers, glycols and aromatic and aliphatic hydrocarbons.


Ethylene glycol n-hexyl ether is a colorless liquid with a slight ether-like odor and bitter taste.
Ethylene glycol n-hexyl ether's miscibility with water, however, is limited.
Ethylene glycol n-hexyl ether is a clear, mobile, neutral, slightly hygroscopic liquid with a mild odor.
As a result, Ethylene glycol n-hexyl ether provides unique cleaning power for removal of both water-soluble and greasy (water insoluble) soils.


Ethylene glycol n-hexyl ether (Ethylene Glycol Monohexyl Ether), n°112-25-4 is measured by GC-FID.
Ethylene glycol n-hexyl ether's vapour is heavier than air.
Since Ethylene glycol n-hexyl ether may react with the oxygen in the air to form peroxides.
Ethylene glycol n-hexyl ether (Cas No.: 112-25-4) is a high boiling pint, slow evaporating rate solvent with excellent solvency characteristics.


Ethylene glycol n-hexyl ether's miscibility with water, however, is limited.
Ethylene glycol n-hexyl ether has the characteristic structure of glycol ethers and contains both ether and alcohol functionalgroups in the same molecule.
Ethylene glycol n-hexyl ether is miscible with all common solvents, e. g. alcohols, ketones, aldehydes, ethers, glycols and aromatic and aliphatic hydrocarbons.


Ethylene glycol n-hexyl ether is a Glycol ether solvent.
n-Hexylglycol enters into the typical reactions of alcohols, e. g. esterification, etherification, oxidation and the formation of alcoholates.
Since Ethylene glycol n-hexyl ether may react with the oxygen in the air to form peroxides, BASF supplies it inhibited with 2,6-di-tert-butyl-para cresol (butylated hydroxytoluene – BHT).


Ethylene glycol n-hexyl ether enters into the typical reactions of alcohols, e. g. esterification, etherification, oxidation and the formation of alcoholates.
Ethylene glycol n-hexyl ether has the characteristic structure of glycol ethers and contains both ether and alcohol functional groups in the same molecule.


Ethylene glycol n-hexyl ether is a high boiling point, slow evaporating rate solvent with excellent solvency characteristics.
Ethylene glycol n-hexyl ether Solvent is a high boiling point, slow evaporating rate solvent with excellent solvencycharacteristics.
Ethylene glycol n-hexyl ether has a high boiling point, slow evaporating solvent with excellent solvency characteristics.



USES and APPLICATIONS of ETHYLENE GLYCOL N-HEXYL ETHER:
Ethylene glycol n-hexyl ether is used to break down soils and grease stains.
Ethylene glycol n-hexyl ether also serves as an intermediate for neopentanoate and hexyloxyethyl phosphate.
Ethylene glycol n-hexyl ether is used as a coalescing agent in latex paints and cleaners.
For instance, it improves the flow of many baking finish systems.


Ethylene glycol n-hexyl ether is used Industry, Scientific Research, Health, Environmental Protection, Agriculture.
Ethylene glycol n-hexyl ether plays an important role in speciality printing inks.
Ethylene glycol n-hexyl ether is used as a chemical intermediate for hexyloxyethyl phosphate and neopentanoate.
Ethylene glycol n-hexyl ether is used Clear, mobile, high-boiling, low-volatility liquid for use as a solvent, flow promoter and coalescent.


Ethylene glycol n-hexyl ether can be used as a solvent for paints, paints, resins, dyes, oils and lubricating oils, as well as coupling and dispersing agents.
By virtue of its good solvent power, the main applications of n-Hexylglycol are as a solvent, flow promoter and coalescent aid.
Ethylene glycol n-hexyl ether is used by professional workers (widespread uses), consumers, in re-packing or re-formulation, in manufacturing, and at industrial sites.


Other uses of Ethylene glycol n-hexyl ether are: Sealants, Adhesives, Coating products, Finger Paints, Fillers, Anti-freeze products, Plasters, Putties, Lubricants, Modelling Clay, Greases, Automotive care products, Machine wash liquids/detergents, Air fresheners, Fragrances, and Other outdoor use.
Ethylene glycol n-hexyl ether serves as a coalescing agent in cleaners and latex paints.


Ethylene glycol n-hexyl ether can also be used in printing inks and cleaners.
Ethylene glycol n-hexyl ether possesses high boiling point.
Usage of Ethylene glycol n-hexyl ether: Laboratory Reagents, Analytical Reagents, Diagnostic Reagents, Teaching Reagents


Ethylene glycol n-hexyl ether is mainly used as a solvent, flow promoter and coalescent aid in the coatings industry and in printing inks and cleaners.
Two solvents, Ethylene glycol n-hexyl ether and diethylene glycol hexyl ether, are potential replacements for halogenated hydrocarbons in non-vapor degreasing applications.


Ethylene glycol n-hexyl ether has excellent oil solubility, making it effective in household and industrial cleaning applications.
Ethylene glycol n-hexyl ether is used as solvent in specialty printing inks, coalescent for water-borne latex-based coatings, primary solvent in solvent-based silk screen printing inks.
Ethylene glycol n-hexyl ether is used as a coalescing agent in latex paints and cleaners.


Ethylene glycol n-hexyl ether can be used as a solvent in lacquers, paints, resins, dyes, oils and lubricants, as well as as a coupling and dispersant.
Ethylene glycol n-hexyl ether is used as a high-boiling solvent.
Ethylene glycol n-hexyl ether is used as special solvent for coating and ink.


Ethylene glycol n-hexyl ether is used as high-boiling solvent.
Ethylene glycol n-hexyl ether is used as a chemical intermediate for hexyloxyethyl phosphate and neopentanoate.
Ethylene glycol n-hexyl ether is used as solvents in speciality printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.


As a result, Ethylene glycol n-hexyl ether provides unique cleaning power for removal of both water-soluble andgreasy (water insoluble) soils.
Ethylene glycol n-hexyl ether can be used as solvent in specialty printing inks.
Ethylene glycol n-hexyl ether plays an important role in specialty printing inks. Because of its limited water solubility andslow evaporation.
Ethylene glycol n-hexyl ether exhibits very good solvency, superior oil solubility, and slow evaporation rate.


Ethylene glycol n-hexyl ether is used for Biological Purpose, For Microscopic Purpose, For Lens Blooming, Technical Grade, Pratical Use, Pro Analysis, Super Special Grade, For Synthesis, For Electrophoresis Use.
Ethylene glycol n-hexyl ethercan be used as coupling agent and solvent in household and industrial clearners, rust removers, hard surface cleaners and disinfectants.


Ethylene glycol n-hexyl ether can be used as coalescent for water-borne.
The linear hexyl portion of this provides excellent oil solubility characteristics that make Ethylene glycol n-hexyl ether useful in both consumer and industrial cleaner applications.
Added in small proportions to formulations for electrodeposition paints, it greatly improves film formation and levelling.


Ethylene glycol n-hexyl ether is also eminently suitable as a mild, low-odour co-solvent in low-aromatic mineral spirit blends for dissolving polymer binders such as Acronal 260 F.
Ethylene glycol n-hexyl ether is mainly used as solvents for cleaning fluids, paints, coatings and ink preparations.


Ethylene glycol n-hexyl ether is used as high-boiling solvent, Solvents (which become part of product formulation or mixture), and Cleaning and furnishing care products.
Because of its limited water solubility and slow evaporation, Ethylene glycol n-hexyl ether can be used in formulations for the silk screen process to prevent premature setting of the ink.


Ethylene glycol n-hexyl ether is used as a coalescing agent for water-based latex-based coatings and plays an important role in specialty printing inks, including screen printing processes, where its limited water solubility and slow evaporation rate prevent premature ink settling.
Ethylene glycol n-hexyl ether is used as solvents in specialty printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.


The linear hexyl portion of Ethylene glycol n-hexyl ether provides excellent oilsolubility characteristics that make it useful in both consumer and industrial cleaner applications.
Ethylene glycol n-hexyl ether can be used in formulations for the silk screen process to prevent premature setting of the ink.
Ethylene glycol n-hexyl ether can be used as primary solvent in solvent-based silk screen printing inks.


Ethylene glycol n-hexyl ether is used as solvents in specialty printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.
Ethylene glycol n-hexyl ether is used as a high-boiling solvent.


-Applications of Ethylene glycol n-hexyl ether:
• Specialty printing inks
• Coalescent for water-borne, latex-based coatings, coupling agent and solvent in household and industrial cleaners, rust removers, hard surface cleaners, and disinfectants
• Primary solvent in solvent-based silk screen printing inks


-Uses of Ethylene glycol n-hexyl ether:
*Cosmetics
*Cleaners
*Textiles
*Waterborne coatings
*Cleaning
*Printing ink



ALTERNATIVE PARENTS of ETHYLENE GLYCOL N-HEXYL ETHER:
*Primary alcohols
*Hydrocarbon derivatives



SUBSTITUENTS of ETHYLENE GLYCOL N-HEXYL ETHER:
*Dialkyl ether
*Hydrocarbon derivative
*Primary alcohol
*Alcohol
*Aliphatic acyclic compound



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENE GLYCOL N-HEXYL ETHER:
Molar mass 146.23 g/mol
n-Hexylglycol: 98.0 min. %
Water: 0.1 max. %
Pt/Co color value (Hazen): 10 max.
Acid value: 0.1 max mg KOH/g
Boiling range at 1013 hPa; 95 Vol.-%; 2 – 97 ml 200 – 212 °C
Density at 20 °C: 0.887 – 0.890 g/cm3
Refractive index: nD20 1.428 – 1.430
Solidification point: at 1013 hPa - 42 °C (ice flakes)
Evaporation rate ether: 1 approx. 1200
Enthalpy of combustion: at 25 °C 33 136 kJ/kg -
Enthalpy of vaporization: at 25 °C 475 kJ/kg -
Enthalpy of vaporization: at boiling point 325 kJ/kg
Enthalpy of formation: at 25 °C - 3 776 kJ/kg -

Dipole moment: (µ) 2.08 D
Solubility Mass fraction of Hexyl glycol in water: 1.0 %
Water in Hexyl glycol: 18.8 %
Water Solubility: 4.22 g/L
logP: 1.82
logP: 1.65
logS: -1.5
pKa (Strongest Acidic): 15.12
pKa (Strongest Basic): -2.7
Physiological Charge: 0
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 1
Polar Surface Area: 29.46 Ų
Rotatable Bond Count: 7

Refractivity: 42.38 m³·mol⁻¹
Polarizability: 18.54 ų
Number of Rings: 0
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: Yes
Veber's Rule: Yes
MDDR-like Rule: Yes
S.G @ 20C/20C: 0.887
Distillation Range C Min: 200
Distillation Range C Max: 212
Evaporation Rate Ether = 1: >1200
Flash Point Deg C: 92
Solubility % wt in Water: @ 20C 1

Appearance and properties: transparent liquid
Density: 0.888 g/mL at 20 °C(lit.)
Boiling point: 98-99°C 0,15mm
Melting point: -45.1ºC
Flash point: 98-99°C/0.15mm
Refractive index: n20/D 1.431
Appearance: Colorless Clear Liquid
Content, GC%Wt: ≥98.0
Acidity,%Wt.(calculated as acetic acid): ≤0.01
Moisture,%Wt: ≤0.15
Chroma, Hazen unit (platinum-cobalt color number): ≤15
Min. Purity Spec: >99% (GC)
Physical Form (at 20°C): Liquid
Melting Point: -42°C

Boiling Point: 208°C
Flash Point: 94°C
Density: 0.89
Refractive Index: 1.43
Long-Term Storage: Store long-term in a cool, dry place
Appearance Form: liquid
Color: colorless
Odor: ether-like
Odor Threshold: No data available
pH: No data available
Melting point/freezing point:
Melting point/range: -50,1 °C at 1.013 hPa
Initial boiling point and boiling range: 208,5 °C at 1.013 hPa

Flash point: 90 °C - closed cup
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: 0,1 hPa at 22,9 °C - OECD Test Guideline 104
Vapor density: No data available
Density: 0,888 g/mL at 20 °C
Relative density: No data available
Water solubility: 9,46 g/l - soluble
Partition coefficient: n-octanol/water:
log Pow: 1,97 at 25 °C
Autoignition temperature: 225 °C at 1.008 - 1.015 hPa
Decomposition temperature: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 4,4 mPa.s at 20 °C
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Appearance (20°)C : Clear Liquid
Color (APHA or less) : 15
Specific gravity (20°C) : 0.887~0.892
Acidity (% or less) : 0.01
Water content (% or less) : 0.2
Purity (% or more) : 98
Molecular Weight: 146.23
XLogP3: 1.9

Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 7
Exact Mass: 146.130679813
Monoisotopic Mass: 146.130679813
Topological Polar Surface Area: 29.5 Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 55.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes


FIRST AID MEASURES of ETHYLENE GLYCOL N-HEXYL ETHER:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing: make victim drink water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ETHYLENE GLYCOL N-HEXYL ETHER:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up carefully with liquid-absorbent material.
Dispose of properly.



FIRE FIGHTING MEASURES of ETHYLENE GLYCOL N-HEXYL ETHER:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENE GLYCOL N-HEXYL ETHER:
-Control parameters
--Ingredients with workplace control parameters
-Exposure controls
--Personal protective equipment
*Eye/face protection
Use equipment for eye protection.
Tightly fitting safety goggles.
*Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Wash and dry hands.
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ETHYLENE GLYCOL N-HEXYL ETHER:
-Precautions for safe handling:
*Hygiene measures:
Immediately change contaminated clothing.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store under inert gas.



STABILITY and REACTIVITY of ETHYLENE GLYCOL N-HEXYL ETHER:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available



SYNONYMS:
2-(Hexyloxy)ethanol
112-25-4
Ethylene glycol monohexyl ether
2-Hexyloxyethanol
Ethanol, 2-(hexyloxy)-
2-HEXOXYETHANOL
Hexyl cellosolve
n-Hexyl cellosolve
Glycol monohexyl ether
Cellosolve, N-hexyl-
2-Hexyloxy-1-ethanol
Ethylene glycol n-hexyl ether
2-n-(Hexyloxy)ethanol
7P0O8282NR
Ethylene glycol mono-n-hexyl ether
DSSTox_CID_6908
DSSTox_RID_78248
2-(hexyloxy)ethan-1-ol
DSSTox_GSID_26908
31726-34-8
Ethanol, 2-hexyloxy-
CAS-112-25-4
Ethylene glycol-n-monohexyl ether
HSDB 5569
EINECS 203-951-1
Hexyl alcohol, ethoxylated
BRN 1734691
UNII-7P0O8282NR
2-hexyloxy-ethanol
MFCD00045997
2-(n-Hexyloxy)ethanol
Ethylenglykolmonohexylether
2-(1-Hexyloxy) ethanol
EC 203-951-1
Ethylene glycol hexyl ether
SCHEMBL24741
4-01-00-02383 (Beilstein Handbook Reference)
CHEMBL3188016
DTXSID1026908
Poly(oxy-1,2-ethanediyl), .alpha.-hexyl-.omega.-hydroxy-
ZINC2041054
Tox21_202105
Tox21_300545
AKOS009156771
NCGC00248089-01
NCGC00248089-02
NCGC00254448-01
NCGC00259654-01
LS-13544
DB-041064
FT-0631642
H0343
EN300-114321
F71224
W-109065
Q27268660
Ethylene glycol monohexyl ether, BioXtra, >=99.0% (GC)
2-(Hexyloxy)ethanol
Hexylglycol
2-(HEXYLOXY)ETHANOL
2-N-(HEXYLOXY)ETHANOL
C6E1
ETHYLENE GLYCOL MONOHEXYL ETHER
ETHYLENE GLYCOL MONO-N-HEXYL ETHER
ETHYLENE GLYCOL N-HEXYL ETHER
HEXYLGLYCOL
N-HEXYL CELLOSOLVE
N-HEXYLMONOOXYETHYLENE
2-(hexyloxy)-ethano
2-Hexoxyethanol
2-hexyloxy-ethano
Cellosolve, n-hexyl-
ethyleneglycol-n-monohexylether
Glycol monohexyl ether
glycolmonohexylether
Hexyl cellosolve
hexylcellosolve
n-hexyl-cellosolv
Ethylenegylcolmono-N-hexylether
2-(Hexyloxy)ethanol
Ethylene glycol monohexyl ether
2-Hexyloxyethanol
Ethanol, 2-(hexyloxy)-
2-HEXOXYETHANOL
Hexyl cellosolve
n-Hexyl cellosolve
Glycol monohexyl ether
Cellosolve, N-hexyl-
2-Hexyloxy-1-ethanol
Ethylene glycol n-hexyl ether
2-n-(Hexyloxy)ethanol
7P0O8282NR
Ethylene glycol mono-n-hexyl ether
DSSTox_CID_6908
DSSTox_RID_78248
DSSTox_GSID_26908
31726-34-8
Ethanol, 2-hexyloxy-
Ethylene glycol-n-monohexyl ether
HSDB 5569
Hexyl alcohol, ethoxylated
BRN 1734691
UNII-7P0O8282NR
2-hexyloxy-ethanol
MFCD00045997
2-(n-Hexyloxy)ethanol
Ethylenglykolmonohexylether
2-(1-Hexyloxy) ethanol
EC 203-951-1
Ethylene glycol hexyl ether
SCHEMBL24741
4-01-00-02383
CHEMBL3188016
DTXSID1026908
Poly(oxy-1,2-ethanediyl), .alpha.-hexyl-.omega.-hydroxy-
ZINC2041054
Tox21_202105
Tox21_300545
AKOS009156771
NCGC00248089-01
NCGC00248089-02
NCGC00254448-01
NCGC00259654-01
LS-13544
DB-041064
FT-0631642
H0343
F71224
W-109065
Q27268660
Ethylene glycol monohexyl ether, BioXtra, >=99.0% (GC)
2-(Hexyloxy)ethanol
Cellosolve, n-hexyl-
Ethanol, 2-hexyloxy-
Ethylene glycol monohexyl ether
Ethylene glycol n-hexyl ether
Ethylene glycol-n-monohexyl ether
Glycol monohexyl ether
Hexyl cellosolve
n-Hexyl cellosolve
C6E1
HEXYLGLYCOL
2-hexyloxyethanol
N-HEXYL CELLOSOLVE
2-(hexyloxy)-ethano
N-HEXYLMONOOXYETHYLENE
ETHYLENE GLYCOL N-HEXYL ETHER
ETHYLENE GLYCOL MONOHEXYL ETHER
ETHYLENE GLYCOL MONO-N-HEXYL ETHER
2-(Hexyloxy)ethanol;2-HEXOXYETHANOL
AC1L1QF7
AC1Q7D9E
Cellosolve, N-hexyl-
EGHE
Ethanol, 2-(hexyloxy)-
Ethanol, 2-hexyloxy-
Ethylene glycol monohexyl ether
Ethylene glycol n-hexyl ether
Ethylene glycol-n-monohexyl ether
Glycol monohexyl ether
H0343
Hexyl alcohol, ethoxylated
Hexyl cellosolve
Hexyl poly(oxyethylene) ether
Hexylglycol
Poly(oxy-1,2-ethanediyl), alpha-hexyl-omega-hydroxy-
SBB060173
alpha-Hexyl,omega-hydroxypoly(oxy-1,2-ethanediyl)
n-Hexyl cellosolve
2- (HEXYLOXY) ETHANOL
2-N-(HEXYLOXY) ETHANOL
C6E1
ETHYLENE GLYCOL MONOHEXYL ETHER
ETHYLENE GLYCOL MONO-N-HEXYL ETHER
ETHYLENE GLYCOL N-HEXYL ETHER
HEXYL GLYCOL
N-HEXYL CELLOSOLVE
N-HEXYLMONOOXYETHYLENE
2-(hexyloxy)-ethane
2-Hexoxyethanol
2-hexyloxy-ethano
Cell fluid, n-hexyl-
ethylene glycol-n-monohexyl ether
Glycol monohexyl ether
glycol monohexyl ether
Hexyl cellosolvation
hexyl cellosolve
n-hexyl-cellosolv
Ethylene gyl carbon mono-N-hexyl ether
Diethylene glycol hexyl ether
2-((2-Hexyloxy)ethoxy)ethanol
Diethylene glycol mono(n-hexyl) ether
Hexol carbitol
Diethylene glycol monohexyl ether
n-Hexoxyethoxyethanol
n-Hexyl carbitol
2-((2-Hexyloxy)ethoxy)ethanol
2-(2-(hexyloxy)ethoxy)ethanol


ETHYLENE GLYCOL N-HEXYL ETHER
Ethylene glycol n-hexyl ether is a high boiling pint, slow evaporating rate solvent with excellent solvency characteristics.
Ethylene glycol n-hexyl ether is typically a clear, colorless liquid with a characteristic mild odor.
Ethylene glycol n-hexyl ether is miscible with water and many organic solvents.

CAS Number: 112-25-4
Molecular Formula: C8H18O2
Molecular Weight: 146.23
EINECS Number: 203-951-1

Ethylene glycol n-hexyl ether is used by professional workers (widespread uses), consumers, in re-packing or re-formulation, in manufacturing, and at industrial sites.
Ethylene glycol n-hexyl ether is used as high-boiling solvent.
Ethylene glycol n-hexyl ether also serves as an intermediate for neopentanoate and hexyloxyethyl phosphate.

Ethylene glycol n-hexyl ether serves as a coalescing agent in cleaners and latex paints.
Ethylene Glycol n-Hexyl Ether's molecular formula is C8H18O2 or C6H13OCH2CH2OH.
Ethylene Glycol n-Hexyl Ether is a high boiling pint, slow evaporating rate solvent with excellent solvency characteristics.

Ethylene glycol n-hexyl ether is an oily colorless liquid with a mild sweet odor.
Ethylene glycol n-hexyl ether, also known as 1,6-Hexanediol, is a chemical compound with the molecular formula C6H14O2.
Ethylene glycol n-hexyl ether is a glycol in which the two hydroxy groups are at positions 2 and 4 of 2-methylpentane (isopentane).

Ethylene Glycol n-Hexyl Ether or 2-(Hexyloxy)ethanol is a glycol ether.
Ethylene Glycol n-Hexyl Ether has a chemical formula of C6H14O2.
Ethylene Glycol n-Hexyl Ether is used as solvents in specialty printing inks and coalescing aids in surface coatings.

The chemical structure consists of a hexyl chain (a six-carbon linear alkyl group) attached to the oxygen atom of an ethylene glycol molecule.
Ethylene Glycol n-Hexyl Ether floats and mixes slowly with water.
Ethylene Glycol n-Hexyl Ether belongs to the class of diols, which are organic compounds containing two hydroxyl (-OH) groups.

The "n" in N-Hexyl Glycol indicates that the carbon chain is linear.
Ethylene Glycol n-Hexyl Ether is a clear, mobile, neutral, slightly hygroscopic liquid with a mild odor.
Ethylene Glycol n-Hexyl Ether is miscible with all common solvents, e. g. alcohols, ketones, aldehydes, ethers, glycols and aromatic and aliphatic hydrocarbons.

Ethylene Glycol n-Hexyl Ether's miscibility with water, however, is limited.
Ethylene Glycol n-Hexyl Ether enters into the typical reactions of alcohols, e. g. esterification, etherification, oxidation and the formation of alcoholates.
Since Ethylene Glycol n-Hexyl Ether may react with the oxygen in the air to form peroxides, BASF supplies it inhibited with 2.6-di-tert-butyl-paracresol Ethylene Glycol n-Hexyl Ether is as a solvent for coatings and degreasing.

Ethylene Glycol n-Hexyl Ether is mainly used as a solvent, flow promoter and coalescent aid in the coatings industry.
Ethylene Glycol n-Hexyl Ether is often referred to by common names such as hexyl cellosolve or hexyl glycol ether.
Ethylene Glycol n-Hexyl Ether finds applications in various industries, including coatings, paints, cleaning products, and as a solvent in different formulations.

Ethylene Glycol n-Hexyl Ether exhibits solvent properties, making it useful in formulations where solubility and dispersing properties are required.
Ethylene Glycol n-Hexyl Ether is commonly used as a solvent in the formulation of coatings and paints, where it aids in achieving the desired viscosity and flow properties.
Ethylene Glycol n-Hexyl Ether may be included in the formulation of cleaning products, such as degreasers and industrial cleaners.

Ethylene Glycol n-Hexyl Ether can be employed as a solvent in the production of inks, contributing to the dispersion of pigments and other ink components.
Ethylene Glycol n-Hexyl Ether is utilized in surface coatings for its ability to improve film formation and enhance the quality of the coating.
Ethylene Glycol n-Hexyl Ether may be used in certain chemical reactions or processes where its unique chemical properties are beneficial.

Ethylene Glycol n-Hexyl Ether is important to handle ethylene glycol n-hexyl ether with care and follow safety guidelines.
This includes using appropriate personal protective equipment and ensuring proper ventilation in areas where it is used.
Ethylene Glycol n-Hexyl Ether is used in printing inks and cleaners.

Ethylene Glycol n-Hexyl Ether is an oxygenated solvent derived from acetone which has two alcohol functions.
Ethylene Glycol n-Hexyl Ether has a low evaporation rate and it is completely miscible with water.
Ethylene Glycol n-Hexyl Ether is mainly used as a solvent or coupling agent.

Ethylene Glycol n-Hexyl Ether is a potential substitute for glycol ethers.
Ethylene Glycol n-Hexyl Ether is also an effective shrinkage reduction admixture or SRA for concrete and mortar.
Ethylene Glycol n-Hexyl Ether is often used in cosmetics and personal care products for its moisturizing properties.

Ethylene Glycol n-Hexyl Ether can contribute to the hydration of the skin when included in formulations such as creams and lotions.
In the flavor and fragrance industry, Ethylene Glycol n-Hexyl Ether can be utilized as a carrier for certain flavors and fragrances.
Ethylene Glycol n-Hexyl Ether is mild odor and solvency make it suitable for use in these applications.

Ethylene Glycol n-Hexyl Ether can be esterified with various acids to produce specific esters.
Esters derived from Ethylene Glycol n-Hexyl Ether may find use in different industries, including the fragrance and flavor industry.
Ethylene Glycol n-Hexyl Ether has been used historically in the production of photographic chemicals.

Ethylene Glycol n-Hexyl Ether also can be used as a coupling agent, rust remover, adhesives and surface cleaners.
Ethylene glycol n-hexyl ether, also known as hexyl cellosolve or hexyl glycol ether, is a chemical compound belonging to the family of glycol ethers.
Ethylene Glycol n-Hexyl Ether is characterized by having a six-carbon linear alkyl chain (hexyl) and an ethylene glycol moiety.

Ethylene Glycol n-Hexyl Ether is soluble in alcohol and ether, water (9.46 g/L ).
Ethylene Glycol n-Hexyl Ether is used as solvents in speciality printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.
Ethylene Glycol n-Hexyl Ether is used as solvent in specialty printing inks, coalescent for water-borne latex-based coatings, primary solvent in solvent-based silk screen printing inks.

Ethylene Glycol n-Hexyl Ether possesses high boiling point.
Ethylene Glycol n-Hexyl Ether exhibits very good solvency, superior oil solubility, and slow evaporation rate.
Ethylene Glycol n-Hexyl Ether is a solvent.

Ethylene Glycol n-Hexyl Ether can be found in a variety of rust removers, hard surface cleaners and disinfectants.
Ethylene Glycol n-Hexyl Ether is used to break down soils and grease stains.
Ethylene Glycol n-Hexyl Ether or 2-(Hexyloxy)ethanol is a glycol ether.

Ethylene Glycol n-Hexyl Ether is used as solvents in specialty printing inks and coalescing aids in surface coatings.
Ethylene Glycol n-Hexyl Ether might be included in the formulation of adhesives and sealants, contributing to the viscosity and performance of these products.
Ethylene Glycol n-Hexyl Ether may be used in the textile industry, where it can aid in the solubilization and application of dyes and other chemicals.

Ethylene Glycol n-Hexyl Ether could be used in formulations for cleaning and degreasing metals in industrial processes.
In the woodworking industry, ethylene glycol n-hexyl ether might be included in wood stains and finishes to improve application properties.
Ethylene Glycol n-Hexyl Ether also can be used as a rust remover.

Ethylene Glycol n-Hexyl Ether is used as solvents in speciality printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.
Ethylene Glycol n-Hexyl Ether is used as high-boiling solvent.
Ethylene Glycol n-Hexyl Ether also serves as an intermediate for hexyloxyethyl phosphate.

Ethylene Glycol n-Hexyl Ether is miscible with water, soluble in ethanol, and soluble in most organic solvents.
Ethylene Glycol n-Hexyl Ether is an oily colorless liquid with a mild sweet odor.
Ethylene Glycol n-Hexyl Ether floats and mixes slowly with water.

Ethylene Glycol n-Hexyl Ether is a glycol in which the two hydroxy groups are at positions 2 and 4 of 2-methylpentane (isopentane).
Ethylene Glycol n-Hexyl Ether is a clear, mobile, neutral, slightly hygroscopic liquid with a mild odor.
Ethylene Glycol n-Hexyl Ether is miscible with all common solvents, e. g. alcohols, ketones, aldehydes, ethers, glycols and aromatic and aliphatic hydrocarbons.

Ethylene Glycol n-Hexyl Ether may be utilized in the formulation of hydraulic brake fluids.
Ethylene Glycol n-Hexyl Ether is properties can contribute to the fluid's ability to transfer pressure and resist high temperatures in braking systems.
In the oil and gas industry, Ethylene Glycol n-Hexyl Ether might be used in the formulation of certain chemicals for oilfield applications, such as drilling fluids or completion fluids.

Ethylene Glycol n-Hexyl Ether can be employed in the formulation of coolants for various cooling systems, helping to maintain proper thermal conditions in industrial processes or automotive engines.
Ethylene Glycol n-Hexyl Ether may serve as a solvent in the pharmaceutical industry for certain drug formulations where its properties are beneficial.
Ethylene Glycol n-Hexyl Ether might be used as a catalyst or co-catalyst in organic synthesis reactions, facilitating specific chemical transformations.

In the field of hydraulic fracturing (fracking), Ethylene Glycol n-Hexyl Ether may find applications in the formulation of fracking fluids used to fracture rocks and extract natural gas or oil.
Ethylene Glycol n-Hexyl Ether can be incorporated into water treatment formulations for cooling towers to prevent scale formation and corrosion.
Ethylene Glycol n-Hexyl Ether's miscibility with water, however, is limited.

Ethylene Glycol n-Hexyl Ether enters into the typical reactions of alcohols, e. g. esterification, etherification, oxidation and the formation of alcoholates.
As a result, Ethylene Glycol n-Hexyl Ether provides unique cleaning power for removal of both water-soluble and greasy (water insoluble) soils.
The linear Ethylene Glycol n-Hexyl Ether portion of this provides excellent oil solubility characteristics that make it useful in both consumer and industrial cleaner applications.

Ethylene Glycol n-Hexyl Ether plays an important role in specialty printing inks.
Because of its limited water solubility and slow evaporation, it can be used in formulations for the silk screen process to prevent premature setting of the ink

Melting point: -45.1℃
Boiling point: 98-99°C 0,15mm
Density: 0.888 g/mL at 20 °C(lit.)
vapor pressure: 10Pa at 20℃
refractive index: n20/D 1.431
Flash point: 98-99°C/0.15mm
storage temp.: -15°C
pka: 14.44±0.10(Predicted)
form: clear liquid
color: Colorless to Light yellow
Water Solubility: Soluble in alcohol and ether, water (9.46 g/L ).
BRN: 1734691
LogP: 1.97 at 25℃

Ethylene glycol n-hexyl ether is considered a VOC, and its use is regulated in certain applications due to environmental and air quality concerns.
In some regions, there are limits on the allowable VOC content in certain consumer products.
Ethylene Glycol n-Hexyl Ether may have film-forming properties, which can be beneficial in applications where the formation of a protective or decorative film is desired, such as in coatings and paints.

Similar to other glycol ethers, ethylene glycol n-hexyl ether may have hygroscopic properties, meaning it can absorb moisture from the air.
Ethylene Glycol n-Hexyl Ether can be used as a chemical intermediate in the synthesis of other compounds.
Some chemical reactions may involve the use of ethylene glycol n-hexyl ether as a starting material.

Due to its solvency, it may find applications in industrial cleaning processes, particularly in formulations designed to remove oils, greases, and other contaminants.
Ethylene Glycol n-Hexyl Ether is an oxygenated solvent derived from acetone which has two alcohol functions.
Ethylene Glycol n-Hexyl Ether is used as a reagent in the synthesis of functionalized boronic esters.

Ethylene Glycol n-Hexyl Ether is used in laboratory studies as a precipitant and cryoprotectant in protein crystallography.
Ethylene Glycol n-Hexyl Ether may find applications in heat transfer fluids, helping to transfer heat efficiently in various industrial processes.
Ethylene Glycol n-Hexyl Ether may be used in analytical chemistry as a solvent or as a component in certain analytical methods.

Ethylene Glycol n-Hexyl Ether is a member of the glycol ether family, which includes various compounds used in different industries for their solvency, stability, and other properties.
Ethylene Glycol n-Hexyl Ether also used in the preparation of vinylboronates.
Ethylene Glycol n-Hexyl Ether is mainly used as a coupling agent and an additive to hydraulic fluids, inks and cement.

Ethylene Glycol n-Hexyl Ether can also be used as a building block in chemical synthesis.
Ethylene Glycol n-Hexyl Etheris also employed as a blood volume expander.
Ethylene Glycol n-Hexyl Ether can be used in formulations for the silk screen process to prevent premature setting of the ink.

Ethylene Glycol n-Hexyl Ether may be used in the tire manufacturing industry as a component in adhesives for tire cord, contributing to the bonding properties of the adhesive.
Ethylene Glycol n-Hexyl Ether may be employed as an antioxidant in fuel formulations to help prevent degradation and improve the stability of the fuel.
Ethylene Glycol n-Hexyl Ether might be considered as a component in wood preservatives, helping to protect wood from decay and insect damage.

Ethylene Glycol n-Hexyl Ether may find applications in the production of materials used in the photovoltaic (solar cell) industry.
Ethylene Glycol n-Hexyl Ether may be used in research and development activities, particularly in laboratories exploring new formulations or chemical processes.
Ethylene Glycol n-Hexyl Ether can be employed in the polymer industry as a component in the synthesis of certain polymers.

Ethylene Glycol n-Hexyl Ether is inclusion may impart specific properties to the resulting polymer.
Ethylene glycol n-hexyl ether might find applications in the automotive industry, such as in the formulation of automotive coatings or cleaning products.
Due to its solvency and film-forming properties, it may be used in the formulation of floor polishes and waxes.

Ethylene Glycol n-Hexyl Ether could be included in formulations for ink removers or cleaning agents designed to remove ink stains.
In the textile printing industry, ethylene glycol n-hexyl ether may be used in ink formulations for printing on fabrics.
Ethylene Glycol n-Hexyl Ether might be used in the formulation of aerosol products, such as spray paints or coatings.

Ethylene Glycol n-Hexyl Ether is generally considered to be biodegradable.
Biodegradability is an important factor in assessing the environmental impact of a chemical.
Ethylene Glycol n-Hexyl Ether could be used in the production of resins, contributing to the overall characteristics of the resin.

Ethylene glycol n-hexyl ether may be employed in the formulation of certain hydraulic fluids, contributing to their lubricating properties.
In the field of inkjet printing, it may find applications in ink formulations for use in inkjet printers.

Ethylene Glycol n-Hexyl Ether is solvency properties make it suitable for use in formulations for metal degreasers, which are used to remove oils and greases from metal surfaces.
In laboratory settings, Ethylene Glycol n-Hexyl Ether might be used as a solvent or as a component in specific experimental setups.

Uses:
Ethylene Glycol n-Hexyl Ether is used as solvents in speciality printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.
Ethylene Glycol n-Hexyl Ether is used by professional workers (widespread uses), consumers, in re-packing or re-formulation, in manufacturing, and at industrial sites.
Ethylene Glycol n-Hexyl Ether is used as high-boiling solvent.

Ethylene Glycol n-Hexyl Ether also serves as an intermediate for neopentanoate and hexyloxyethyl phosphate.
Ethylene Glycol n-Hexyl Ether serves as a coalescing agent in cleaners and latex paint.
Ethylene Glycol n-Hexyl Ether can be used as solvent in specialty printing inks.

Ethylene Glycol n-Hexyl Ether can be used as coalescent for water-borne
Ethylene Glycol n-Hexyl Ether can be used as solvent in specialty printing inks.
Ethylene Glycol n-Hexyl Ether can be used as coalescent for water-borne.

Ethylene Glycol n-Hexyl Ether can be used as coupling agent and solvent in household and industrial clearners, rust removers, hard surface cleaners and disinfectants.
Ethylene Glycol n-Hexyl Ether is a fine chemical product with a wide range of uses, which can be used in pesticides, biochemical engineering, photosensitive materials, synthetic fragrances and other fields.
Ethylene Glycol n-Hexyl Ether is a highly soluble high-grade organic solvent.

Ethylene Glycol n-Hexyl Ether can be used as an additive in the production of metal surface treatment agents for rust and oil removal.
Ethylene Glycol n-Hexyl Ether can also be used as a textile auxiliaries, as well as coatings and latex paints.
Ethylene Glycol n-Hexyl Ether can also be used in cosmetics, as a pesticide stabilizer, but also as a daily chemical moisturizer, flavor and fragrance raw materials, hydraulic oil, high-temperature lubricating oil, brake oil, dry cleaning agent, printing ink, pigment dispersant, wood preservative etc.

Ethylene Glycol n-Hexyl Ether can be used as primary solvent in solvent-based silk screen printing inks.
Ethylene Glycol n-Hexyl Ether is used as a solvent in the formulation of coatings and paints to improve viscosity, flow, and film-forming properties.
Included in industrial cleaners and degreasers due to its solvency, helping to remove oils, greases, and contaminants.

Ethylene Glycol n-Hexyl Ether employed as a solvent in the production of inks for various printing applications, such as inkjet printing and textile printing.
Ethylene Glycol n-Hexyl Ether found in automotive coatings, cleaning products, and formulations where its solvent properties are beneficial.
Included in the formulation of adhesives and sealants, contributing to viscosity and performance.

Ethylene Glycol n-Hexyl Ether is used in the production of floor polishes and waxes, where it helps in achieving a smooth and protective finish.
Applied in the textile industry for solubilizing dyes and other chemicals used in fabric treatments.
Ethylene Glycol n-Hexyl Ether found in the formulation of aerosol products, including spray paints and coatings.

Ethylene Glycol n-Hexyl Ether is used in industrial processes for cleaning and degreasing metal surfaces.
Ethylene Glycol n-Hexyl Ether may find applications in the production of materials used in the photovoltaic (solar cell) industry.
Ethylene Glycol n-Hexyl Ether is used as a component in the synthesis of certain polymers, contributing specific properties to the final polymer.

Included in the formulation of hydraulic fluids or other automotive fluids where its properties are beneficial.
Ethylene Glycol n-Hexyl Ether employed in woodworking for improving the application properties of wood stains and finishes.
Ethylene Glycol n-Hexyl Ether is used in formulations for ink removers or cleaning agents designed to remove ink stains.

Ethylene Glycol n-Hexyl Ether found in ink formulations for textile printing on fabrics.
Considered biodegradable, making it suitable for applications where environmental impact is a concern.
Ethylene Glycol n-Hexyl Ether is used in the production of resins, contributing to the characteristics of the resin.
Hydraulic Fluids:

Ethylene Glycol n-Hexyl Ether is used in formulations for metal degreasers to remove oils and greases from metal surfaces.
Ethylene Glycol n-Hexyl Ether is used in laboratories as a solvent or a component in specific experimental setups where its properties are advantageous.
Ethylene Glycol n-Hexyl Ether may be utilized as a component in fuel additives to enhance stability and performance.

Ethylene Glycol n-Hexyl Ether found in the formulation of coolants and heat transfer fluids where it helps maintain proper thermal conditions.
Ethylene Glycol n-Hexyl Ether included as a component in wood preservatives to protect wood from decay and insect damage.
Ethylene Glycol n-Hexyl Ether is used in the production of surfactants where its properties contribute to the stability of emulsions or foams.

Ethylene Glycol n-Hexyl Ether is used in the formulation of deicing fluids, particularly in applications where prevention of ice formation is crucial.
Included as an additive in concrete formulations to improve workability and setting time.
Utilized in the oil and gas industry for the formulation of certain chemicals used in oilfield applications.

Ethylene Glycol n-Hexyl Ether may be used in the formulation of hydraulic brake fluids for automotive applications.
Ethylene Glycol n-Hexyl Ether is used as a reagent in the synthesis of functionalized boronic esters.
Ethylene Glycol n-Hexyl Ether is used in laboratory studies as a precipitant and cryoprotectant in protein crystallography.

Ethylene Glycol n-Hexyl Ether is used as a carrier for certain flavors and fragrances in the flavor and fragrance industry.
Ethylene Glycol n-Hexyl Ether found in the formulation of metalworking fluids, providing lubrication and cooling during machining processes.
Ethylene Glycol n-Hexyl Ether is used as an additive in concrete formulations to improve workability and setting time.

Safety profile:
According to the European Chemicals Agency, Ethylene Glycol n-Hexyl Ether is classified as harmful when in contact with skin and when swallowed.
Ethylene Glycol n-Hexyl Ether can also cause skin burns and serious eye damage.
Ethylene Glycol n-Hexyl Ether was also known to cause kidney injury and depression.

Ethylene Glycol n-Hexyl Ether is also a severe respiratory tract irritant.
Ethylene Glycol n-Hexyl Ether may also have blood effects.
Ethylene Glycol n-Hexyl Ether may enter the body through ingestion, aerosol inhalation, and through the skin.

Ethylene Glycol n-Hexyl Ether may form explosive peroxides.
Ethylene Glycol n-Hexyl Ether can react violently with strong oxidants.
Ethylene Glycol n-Hexyl Ether is classified as a green circle product EPA Safer Choice meaning it is of low concern.

Ethylene glycol n-hexyl ether may cause irritation to the skin and eyes upon contact.
Ethylene Glycol n-Hexyl Ether is important to use appropriate personal protective equipment, such as gloves and safety goggles, to prevent direct contact.
Inhalation of vapors or mists of ethylene glycol n-hexyl ether may cause respiratory irritation.

Adequate ventilation should be maintained in areas where it is used, and respiratory protection may be necessary.
Ingesting ethylene glycol n-hexyl ether can be harmful.

Ethylene Glycol n-Hexyl Ether is not intended for consumption, and ingestion may lead to adverse health effects.
While not highly flammable, ethylene glycol n-hexyl ether may pose a fire hazard under certain conditions.
Precautions should be taken to prevent ignition sources in areas where it is handled.

Synonyms:
2-(Hexyloxy)ethanol
112-25-4
Ethylene glycol monohexyl ether
2-Hexyloxyethanol
Ethanol, 2-(hexyloxy)-
2-HEXOXYETHANOL
Hexyl cellosolve
n-Hexyl cellosolve
Glycol monohexyl ether
Cellosolve, N-hexyl-
Ethylene glycol n-hexyl ether
2-Hexyloxy-1-ethanol
DTXSID1026908
7P0O8282NR
Ethylene glycol mono-n-hexyl ether
DTXCID606908
Ethanol, 2-hexyloxy-
2-(hexyloxy)ethan-1-ol
CAS-112-25-4
Ethylene glycol-n-monohexyl ether
HSDB 5569
2-n-(Hexyloxy)ethanol
EINECS 203-951-1
BRN 1734691
UNII-7P0O8282NR
2-hexyloxy-ethanol
MFCD00045997
2-(n-Hexyloxy)ethanol
Ethylenglykolmonohexylether
2-(1-Hexyloxy) ethanol
EC 203-951-1
SCHEMBL24741
31726-34-8
4-01-00-02383 (Beilstein Handbook Reference)
CHEMBL3188016
Tox21_202105
Tox21_300545
AKOS009156771
NCGC00248089-01
NCGC00248089-02
NCGC00254448-01
NCGC00259654-01
LS-13544
FT-0631642
H0343
EN300-114321
F71224
W-109065
Q27268660
Ethylene glycol monohexyl ether, BioXtra, >=99.0% (GC)
Ethylene Karbonat
SYNONYMS Ethylene Glycol Carbonate; 1,3-dioxolan-2-one;Glycol Carbonate; Dioxolone-2; Cyclic Ethylene Carbonate; Ethylene Carbonic Acid; Carbonic Acid, Cyclic Ethylene Ester; CAS NO:96-49-1
ETHYLENE UREA
CAS No.: 120-93-4
EC No.: 204-436-4
Molecular Weight: 86.09 g/mol
IUPAC Name: imidazolidin-2-one
Molecular Formula: C3H6N2O


DESCRIPTION:
2-Imidazolidone (Ethylene Urea) is a white crystalline powder, which can be dissolved in water.
Ethylene urea serves mainly as a formaldehyde scavenger and chemical building block.
Apart from the textile industry Ethylene urea is used in construction and coatings industry applications.
The Ethylene Urea 87% - also known as 2-Imidazolidinone hemihydrate – is mainly used in various kinds of formaldehyde removing formulations such as high-effect formaldehyde removing detergents and long-term formaldehyde dissolution intermediates.
In the flavor and fragrance industry the product is used as a release control agent.
The pharma industry is using the product as an intermediate for antibiotics such as Mezlocillin and Azlocillin.


Ethylene urea is an organic compound derived from formaldehyde and urea.
Ethylene urea is a colourless solid that is used for treating cellulose-based heavy fabrics to inhibit wrinkle formation.
Ethylene urea (DMEU) bonds with the hydroxyl groups present in long cellulose chains and prevents the formation hydrogen bonding between the chains, the primary cause of wrinkling.

This treatment produces permanently wrinkle-resistant fabrics and is different from the effects achieved from using fabric softeners.
An additional names for Ethylene urea includes 1,3-bis(hydroxymethyl)-tetrahydro-2-imidazolone


Main users are the leather, rubber, fragrance and textile coating industry.

APPLICATIONS OF ETHYLENE UREA:
• Textile auxiliaries
• Fragrance
• Pharma
Ethylene urea can be very affective at scavenging formaldehyde in various resin systems.
Reduction of 75% can be achieved depending on application conditions and the resin system properties.
The exact amount needed would depend on many variables, but laboratory experimentation should be performed to establish optimized dosage.
1. Textile industry
Cotton products are composed by long chain cellulose, which contains lots of hydroxyls to form spacious hydrogen bonds.
These hydrogen bonds will be broken and then randomly reformed under the heat or external forces. That’s how the fabric folds come.

2-Imidazolidone (Ethylene Urea) reacts with hydroxyl groups when treating fabrics together with formaldehyde, forming a stable structure to prevent the folds from forming.
This method can also restain the pungent odor caused from using formaldehyde only as the anti-wrinkle treatment by effectively inhibiting the release of formaldehyde.

Besides, urea resin is another widely used textile finishing agent.
Its residues on fabrics slowly release formaldehyde, which can be effectively inhibited by 2-Imidazolidone (Ethylene Urea).

Coating and Paint:
2-Imidazolidone (Ethylene Urea) can be used as de-aldehyde agent in poly-EVA, all kinds of water-based coatings, paints, pigments, adhesives and paper industry.
Ethylene Urea can also be added to the paint alone to make the paint absorbing and decomposing formaldehyde.

Ink for inkjet printers:
2-Imidazolidone (Ethylene Urea) is an important additives of ink for inkjets.
Ethylene Urea can disperse the pigment, lubricate the channels, prevent nozzles from drying out and blocking, and imporve the storage stability of ink.
Ethylene Urea can also imporve the color contrast to enhance the printing effect.

Adhesive:
Various types of artificial panels such as plywood, chipboard, fiberboard and composite panels, usually choose urea resin, phenolic resin or melamine resin as adhesives.
Those adhesives are produced from polycondensation between formaldehyde and urea, phenol or melamine respectively.
All of them have the problem of slowly releasing gaseous formaldehyde into the environment.
2-Imidazolidone (Ethylene Urea) can be added to effectively reduce the formaldehyde release and does not affect the bonding effect.

Daily Chemical:
2-Imidazolidone (Ethylene Urea) is the main composition of household de-aldehyde agent.
Ethylene Urea can be used as high-performance formaldehyde remover, home air formaldehyde potent enzyme, formaldehyde long-acting melting medium, aldehyde remover for glue, photocatalyst, floor deodorization care wax, furniture deodorizer, car deodorizer, etc.

Organic Synthesis:
2-Imidazolidone (Ethylene Urea) can be used as intermediates of many new antibiotics, such as meloxicillin and aloxicillin, as intermediates for anti-schistosomiasis drugs, and as basic raw materials of third-generation penicillin.
In the biological field, Ethylene Urea can be used to produce the plant growth regulators, fungicides, inhibitors, herbicides, etc., such as: N-chlorocarbonyl-2-imidazolidinone, 1-chlorocarbonyl-3-acetyl-2-imidazolidinone, 1-chlorocarbonyl-3-methanesulfonyl-2-imidazolidinone N-chloroformyl-2-imidazolidinone, 1-chloroformyl-3-acetyl-2-imidazolidinone, 1-chloroformyl-3-methanesulfonyl-2-imidazolidinone, N-hydroxyethyl-2-imidazolidinone, 1-methanesulfonyl-2-imidazolidinone, 1,3-dimethyl-2-imidazolidinone, 1-acetyl-2-imidazolidinone, etc




CAS No.: 120-93-4
EC No.: 204-436-4
Molecular Weight: 86.09 g/mol
IUPAC Name: imidazolidin-2-one
Molecular Formula: C3H6N2O




USES OF ETHYLENE UREA:
Ethylene urea is an organic intermediate used in various chemical industries.
Ethylene urea was originally used for the production of dimethylol ethylene urea thermosetting resins in textiles and paper.
Ethylene urea is also used as a scavenging agent to reduce the free formaldehyde in phenolic, melamine, glyoxal and urea formaldehyde resin systems for the coatings, construction and textile industries.

STORAGE CONDITIONS OF ETHYLENE UREA:
Ethylene urea has a shelf life of at least twelve months from the date of delivery; if stored in original unopened containers at temperatures not exceeding 30°C (86°F).
Continued storage beyond the designated shelf life does not necessarily mean the material cannot be used.
However, renewed testing of the most important properties is imperative.





CHEMICAL AND PHYSICAL PROPERTIES OF ETHYLENE UREA:
Molecular Weight: 86.09
XLogP3: -1.3
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 0
Exact Mass: 86.048012819
Monoisotopic Mass: 86.048012819
Topological Polar Surface Area: 41.1 Ų
Heavy Atom Count: 6
Formal Charge: 0
Complexity: 63.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Appearance: Clear Liquid
Color (APHA): <150
pH (neat): 6.0 to 7.0
Viscosity (cps): <100
Density (lbs / gal): 9.0 to 9.26


CAS No.: 120-93-4
EC No.: 204-436-4
Molecular Weight: 86.09 g/mol
IUPAC Name: imidazolidin-2-one
Molecular Formula: C3H6N2O

SAFETY INFORMATION ABOUT ETHYLENE UREA:

First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.





CAS No.: 120-93-4
EC No.: 204-436-4
Molecular Weight: 86.09 g/mol
IUPAC Name: imidazolidin-2-one
Molecular Formula: C3H6N2O






SYNONYMS OF ETHYLENE UREA:
MeSH Entry Terms:
2-imidazolidinone
ethylene urea
imidazolidin-2-one

Depositor-Supplied Synonyms:
2-Imidazolidone
imidazolidin-2-one
120-93-4
2-Imidazolidinone
ETHYLENEUREA
imidazolidinone
Ethylene urea
N,N'-Ethyleneurea
2-Oxoimidazolidine
1,3-Ethyleneurea
Imidazolid-2-one
Monoethyleneurea
2-Oxomidazolidine
Urea, 1,3-ethylene-
SD 6073
2-imidazolidinon
Urea, N,N'-(1,2-ethanediyl)-
NSC 21314
CHEBI:37001
Urea,3-ethylene-
NSC-21314
WLN: T5MVMTJ
2K48456N55
Urea,N'-(1,2-ethanediyl)-
HSDB 4021
EINECS 204-436-4
imidazolidone
2-imidazolinone
AI3-22151
imidazolin-2-one
UNII-2K48456N55
Imidazoliden-2-one
2-oxo-imidazolidine
MFCD00005257
2-Imidazolidone, 96%
DSSTox_CID_602
EC 204-436-4
ETHYLENEUREA [HSDB]
DSSTox_RID_75683
DSSTox_GSID_20602
CHEMBL12034
IMIDAZOLIDINONE [INCI]
2-IMIDAZOLIDINONE [MI]
DTXSID0020602
NSC3338
NSC-3338
NSC21314
ZINC1666720
Tox21_200783
AKOS000121325
7-Benzyloxy-1H-indole-3-carboxylicacid
NCGC00248832-01
NCGC00258337-01
AS-13128
BP-21148
CAS-120-93-4
DB-021217
DB-021218
AM20080146
CS-0075560
FT-0626340
FT-0668259
I0005
EN300-21266
D71145
2-Imidazolidinon 100 microg/mL in Acetonitrile
A804620
2-Imidazolidone, PESTANAL(R), analytical standard
Q-200290
Q2813813
F0001-0335
Z104494954
Ethyleneamine E-100 (E-100)
SYNONYMS 1,2-Ethylenediamine; 1,2-Diaminoethane; EDA;Ethane-1,2-diamine; Aethaldiamin (German); Aethylenediamin (German); 1,2-diaminoaethan (German) ; 1,2-Diamino-ethaan (Dutch); 1, 2-Diamino-Ethano (Italian); Dimethylenediamine; Ethyleendiamine (Dutch); Ethylene-diamine (French); β-Aminoethylamine; 乙二胺 (Chinese) CAS NO:107-15-3
ETHYLENEDIAMINE
ETHYLENEDIAMINE = EDA

Ethylenediamine (abbreviated as en when a ligand) is the organic compound with the formula C2H4(NH2)2.
This colorless liquid with an ammonia-like odor is a basic amine.
Ethylenediamine is the first member of the so-called polyethylene amines.

CAS Number: 107-15-3
EC Number: 203-468-6
Chemical Formula: H2NCH2CH2NH2
Molar Mass: 60.10 g/mol

EDA is used as a building block for the synthesis of bleach activators, chelates and crop protection products.
Furthermore is used as an intermediate in applications like corrosion inhibitors, polyamide resins and lubricants/fuel additives.

Ethylenediamine is chain extender in the production of poyurethane resin for the water PU Dispersion (PUD).
Products derived from EDA are frequently used for bleach activators and chelates in detergents and for fungicides in crop protection area.

Polyamide resins find wide use as binders in printing inks for flexogravure application on certain paper, film, and foil webs and in hot-melt, pressure-sensitive, and heat-seal adhesives for leather, paper, plastic, and metal.
The main polyamide resin type, in addition to the liquid resins used as epoxy hardeners, is prepared generally by the condensation reaction of diamines with di- and polybasic fatty acids.

Thermoplastic polyamides are similarly used in formulating glossy, abrasion-resistant, overprint varnishes.
EDA is available as pure substance.

Ethylenediamine is a single-component product with two primary nitrogens.
Ethylenediamine has an ammonia-like odor and is clear and colorless.
Ethylenediamine is a widely used building block in chemical synthesis, with approximately 500,000 tonnes produced in 1998.

Ethylenediamine is an inflammable substance.
Ethylenediamine reacts severely to aldehyde and acids.

Ethylenediamine absorbs the carbon dioxide in the air.
Ethylenediamine is hygroscopic and resolves in water, ether, benzene, acetone and hexane.

Ethylenediamine (abbreviated as en when a ligand) is the organic compound with the formula C2H4(NH2)2.
This colorless liquid with an ammonia-like odor is a basic amine.

Ethylenediamine is a widely used building block in chemical synthesis, with approximately 500,000 tonnes produced in 1998.
Ethylenediamine is the first member of the so-called polyethylene amines.

Ethylenediamine (EDA) is the ethyleneamine with the lowest molecular weight.
Ethylenediamine contains two primary amine groups and is a colorless liquid.
Ethylenediamine is commonly used as an intermediate to produce detergents, chelates, textile auxiliaries, agrochemicals and polyamides.

Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products.
Ethylenediamine is also used as an excipient in many pharmacological preparations such as creams.

Notably, ethylenediamine is a contact sensitizer capable of producing local and generalized reactions.
Sensitivity to ethylenediamine may be identified with a clinical patch test.

Ethylenediamine is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 tonnes per annum.
Ethylenediamine is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Ethylenediamine appears as a clear colorless liquid with an ammonia-like odor.
Ethylenediamine is flash point of 91 °F and a melting point of 47 °F.

Ethylenediamine is corrosive to tissue.
Ethylenediamine is vapors are heavier than air.

Ethylenediamine is produces toxic oxides of nitrogen during combustion.
Ethylenediamine is density 7.5 lb / gal.
Ethylenediamine is used to make other chemicals and as a fungicide.

Ethylenediamine is an alkane-alpha,omega-diamine in which the alkane is ethane.
Ethylenediamine has a role as a GABA agonist.
Ethylenediamine derives from a hydride of an ethane.

Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products.
Ethylenediamine is also used as an excipient in many pharmacological preparations such as creams.

Notably, ethylenediamine is a contact sensitizer capable of producing local and generalized reactions.
Sensitivity to ethylenediamine may be identified with a clinical patch test.

Usage Area of Ethylenediamine:
Ethylenediamine is used in the textile sector.
Ethylenediamine is used the fields of fiber, polyamide and rubber.

Ethylenediamine is used as a chelator and a corrosion inhibitor.
Ethylenediamine is used as a lubricant in the plastics sector.
Ethylenediamine is used in foam making operations.

Uses of Ethylenediamine:
Ethylenediamine is used in the manufacture of chelating agents, fungicides, waxes, polyamide resins, and corrosion inhibitors.
Ethylenediamine is used as an emulsifier, an inhibitor in antifreeze solutions, and an additive to pharmaceuticals and textile lubricants.

Ethylenediamine is used in photography (color developing baths).
Ethylenediamine is used in prepn of dyes, synthetic waxes, resins, insecticides and asphalt wetting agents.

Drug Indication:
Ethylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.

Widespread uses by professional workers:
Ethylenediamine is used in the following products: adhesives and sealants, coating products, pH regulators and water treatment products, fillers, putties, plasters, modelling clay and water treatment chemicals.
Ethylenediamine is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment, health services and scientific research and development.
Other release to the environment of Ethylenediamine is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

Uses at industrial sites:
Ethylenediamine is used in the following products: pH regulators and water treatment products, adhesives and sealants, coating products, heat transfer fluids, hydraulic fluids and polymers.
Ethylenediamine has an industrial use resulting in manufacture of another substance (use of intermediates).

Ethylenediamine is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Ethylenediamine is used for the manufacture of: chemicals.
Release to the environment of Ethylenediamine can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture, in processing aids at industrial sites, of substances in closed systems with minimal release, in the production of articles and as processing aid.

Industry Uses:
Hardener
Intermediate
Intermediates
Processing aids, specific to petroleum production
Soil amendments (fertilizers)

Industrial Processes with risk of exposure:
Textiles (Fiber & Fabric Manufacturing)
Painting (Pigments, Binders, and Biocides)
Photographic Processing

Other Uses of Ethylenediamine:
Corrosion inhibitors
Wet-strength resins
Fabric softeners
Epoxy curing agents
Polyamide resins
Fuel additives
Lube oil additives
Asphalt additives
Ore flotation
Corrosion inhibitors
Ore flotation
Asphalt
Additives
Corrosion inhibitors
Epoxy curing agents
Hydrocarbon purification
Lube oil & fuel additives
Mineral processing aids
Polyamide resins
Surfactants
Textile additives-paper wet-strength resins
Fabric softeners
Surfactants
Coatings
Urethanes
Fuel additives
Chemical intermediates
Epoxy curing agents
Lube oils
Wet strength resins

Applications of Ethylenediamine:
Ethylenediamine is used in large quantities for production of many industrial chemicals.
Ethylenediamine forms derivatives with carboxylic acids (including fatty acids), nitriles, alcohols (at elevated temperatures), alkylating agents, carbon disulfide, and aldehydes and ketones.
Because of Ethylenediamine bifunctional nature, having two amines, Ethylenediamine readily forms heterocycles such as imidazolidines.

Precursor to chelation agents, drugs, and agrochemicals:
A most prominent derivative of ethylenediamine is the chelating agent EDTA, which is derived from ethylenediamine via a Strecker synthesis involving cyanide and formaldehyde.
Hydroxyethylethylenediamine is another commercially significant chelating agent.

Numerous bio-active compounds and drugs contain the N-CH2-CH2-N linkage, including some antihistamines.
Salts of ethylenebisdithiocarbamate are commercially significant fungicides under the brand names Maneb, Mancozeb, Zineb, and Metiram.
Some imidazoline-containing fungicides are derived from ethylenediamine.

Pharmaceutical Ingredient:
Ethylenediamine is an ingredient in the common bronchodilator drug aminophylline, where Ethylenediamine serves to solubilize the active ingredient theophylline.
Ethylenediamine has also been used in dermatologic preparations, but has been removed from some because of causing contact dermatitis.

When used as a pharmaceutical excipient, after oral administration Ethylenediamine bioavailability is about 0.34, due to a substantial first-pass effect.
Less than 20% is eliminated by renal excretion.

Ethylenediamine-derived antihistamines are the oldest of the five classes of first-generation antihistamines, beginning with piperoxan aka benodain, discovered in 1933 at the Pasteur Institute in France, and also including mepyramine, tripelennamine, and antazoline.
The other classes are derivatives of ethanolamine, alkylamine, piperazine, and others (primarily tricyclic and tetracyclic compounds related to phenothiazines, tricyclic antidepressants, as well as the cyproheptadine-phenindamine family)

Role in Polymers:
Ethylenediamine, because Ethylenediamine contains two amine groups, is a widely used precursor to various polymers.
Condensates derived from formaldehyde are plasticizers.

Ethylenediamine is widely used in the production of polyurethane fibers.
The PAMAM class of dendrimers are derived from ethylenediamine.

Tetraacetylethylenediamine:
The bleaching activator tetraacetylethylenediamine is generated from ethylenediamine.
The derivative N,N-ethylenebis(stearamide) (EBS) is a commercially significant mold-release agent and a surfactant in gasoline and motor oil.

Other Applications:
As a solvent, Ethylenediamine is miscible with polar solvents and is used to solubilize proteins such as albumins and casein.
Ethylenediamine is also used in certain electroplating baths.

As a corrosion inhibitor in paints and coolants.
Ethylenediamine dihydroiodide (EDDI) is added to animal feeds as a source of iodide.

Chemicals for color photography developing, binders, adhesives, fabric softeners, curing agents for epoxies, and dyes.
As a compound to sensitize nitromethane into an explosive.
This mixture was used at Picatinny Arsenal during WWII, giving the nitromethane and ethylenediamine mixture the nickname PLX, or Picatinny Liquid Explosive.

Benefits of Ethylenediamine:
Consistent and predictable reaction products
Easily derivatized
Low vapor pressure
High viscosity
Low environmental impact
Suitable for harsh conditions
Low sensitivity
Versatile

Functions of Ethylenediamine:
Raw Material,
Scale inhibitor,
Chemical Intermediate,
Chemical Reagent,
Dispersing Agent,
Scale Removal and Control

Human Metabolite Information of Ethylenediamine:

Tissue Locations:
Kidney
Liver

Cellular Locations:
Cytoplasm
Extracellular

Synthesis of Ethylenediamine:
Ethylenediamine is produced industrially by treating 1,2-dichloroethane with ammonia under pressure at 180 °C in an aqueous medium.

In this reaction hydrogen chloride is generated, which forms a salt with the amine.
The amine is liberated by addition of sodium hydroxide and can then be recovered by rectification.
Diethylenetriamine (DETA) and triethylenetetramine (TETA) are formed as by-products.

Another industrial route to ethylenediamine involves the reaction of ethanolamine and ammonia.

This process involves passing the gaseous reactants over a bed of nickel heterogeneous catalysts.

Ethylenediamine can be produced in the lab by the reaction of ethylene glycol and urea.
Ethylenediamine can be purified by treatment with sodium hydroxide to remove water followed by distillation.

General Manufacturing Information of Ethylenediamine:

Industry Processing Sectors:
Agriculture, Forestry, Fishing and Hunting
All Other Basic Inorganic Chemical Manufacturing
All Other Basic Organic Chemical Manufacturing
All Other Chemical Product and Preparation Manufacturing
Not Known or Reasonably Ascertainable
Oil and Gas Drilling, Extraction, and Support activities
Paint and Coating Manufacturing
Petrochemical Manufacturing
Petroleum Refineries
Pharmaceutical and Medicine Manufacturing
Wholesale and Retail Trade

Coordination Chemistry of Ethylenediamine:
Ethylenediamine is a well-known bidentate chelating ligand for coordination compounds, with the two nitrogen atoms donating their lone pairs of electrons when ethylenediamine acts as a ligand.
Ethylenediamine is often abbreviated "en" in inorganic chemistry.

The complex [Co(ethylenediamine)3]3+ is an archetypical chiral tris-chelate complex.
The salen ligands, some of which are used in catalysis, are derived from the condensation of salicylaldehydes and ethylenediamine.

Related ligands:
Related derivatives of ethylenediamine include ethylenediaminetetraacetic acid (EDTA), tetramethylethylenediamine (TMEDA), and tetraethylethylenediamine (TEEDA).
Chiral analogs of ethylenediamine include 1,2-diaminopropane and trans-diaminocyclohexane.

Handling and Storage of Ethylenediamine:

Nonfire Spill Response:
ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.
All equipment used when handling the product must be grounded.

Do not touch or walk through spilled material.
Stop leak if you can do Ethylenediamine without risk.

Prevent entry into waterways, sewers, basements or confined areas.
A vapor-suppressing foam may be used to reduce vapors.

Absorb with earth, sand or other non-combustible material.
For hydrazine, absorb with DRY sand or inert absorbent (vermiculite or absorbent pads).
Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL:
Dike far ahead of liquid spill for later disposal.
Water spray may reduce vapor, but may not prevent ignition in closed spaces.

Safe Storage:
Separated from strong oxidants, acids, chlorinated organic compounds and food and feedstuffs.
Store only in original container.

Storage Conditions:
Outside or detached storage is preferred.
Avoid oxidizing materials, acids, and sources of halogens.
Store in a cool, dry, well-ventilated location.

Safety of Ethylenediamine:
Ethylenediamine, like ammonia and other low-molecular weight amines, is a skin and respiratory irritant.
Unless tightly contained, liquid ethylenediamine will release toxic and irritating vapors into Ethylenediamine surroundings, especially on heating.
The vapors absorb moisture from humid air to form a characteristic white mist, which is extremely irritating to skin, eyes, lungs and mucus membranes.

First Aid Measures of Ethylenediamine:
Exposure to ethylenediamine may result in cough, difficulty in breathing, irritation of the lungs, and pneumonia.
Nausea, vomiting, and diarrhea are often seen.
Contact with ethylenediamine may result in redness, pain, irritation, and burns.

Emergency Life-Support Procedures:
Exposure to ethylenediamine may require decontamination and life support for the victims.
Emergency personnel should wear protective clothing appropriate to the type and degree of contamination.

Air-purifying or supplied-air respiratory equipment should also be worn, as necessary.
Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air.
Emergency personnel should avoid self-exposure to ethylenediamine.

2. Evaluate vital signs including pulse and respiratory rate, and note any trauma.
If no pulse is detected, provide CPR.

If not breathing, provide artificial respiration.
If breathing is labored, administer oxygen or other respiratory support.

3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

4. Transport to a health care facility.

Dermal/Eye Exposure:

1. Remove victims from exposure.
Emergency personnel should avoid self- exposure to ethylenediamine.

2. Evaluate vital signs including pulse and respiratory rate, and note any trauma.
If no pulse is detected, provide CPR.

If not breathing, provide artificial respiration.
If breathing is labored, administer oxygen or other respiratory support.

3. Remove contaminated clothing as soon as possible.

4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.

5. Thoroughly wash exposed skin areas with water for at least 15 minutes.

6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

7. Transport to a health care facility.

Ingestion Exposure:

1. Evaluate vital signs including pulse and respiratory rate, and note any trauma.
If no pulse is detected, provide CPR.

If not breathing, provide artificial respiration.
If breathing is labored, administer oxygen or other respiratory support.

2. DO NOT induce vomiting.

3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

4. Activated charcoal is of no value.

5. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults, 250 mL (8 oz or 1 cup).
Water or milk should be given only if victims are conscious and alert.

6. Transport to a health care facility.

Fire Fighting of Ethylenediamine:
Wear full protective clothing including gloves and boots.
If necessary to enter closed area, wear full-faced gas masks with self-contained breathing apparatus.

Use water spray, dry chemical, alcohol foam, or carbon dioxide.
Do not use water in case of drum or tank fires.

If a leak or spill has not ignited, use water spray to reduce the vapors and dilute spills to nonflammable mixtures.
Use water to keep fire-exposed containers cool.

Fire Fighting Procedures:
Use water spray, dry chem, "alcohol resistant" foam, or carbon dioxide. Use water spray to keep fire-exposed containers cool.
Solid streams may be ineffective and spread material.

Identifiers of Ethylenediamine:
CAS Number: 107-15-3
Abbreviations: en
Beilstein Reference: 605263
ChEBI: CHEBI:30347
ChEMBL: ChEMBL816
ChemSpider: 13835550
ECHA InfoCard: 100.003.154
EC Number: 203-468-6
Gmelin Reference: 1098
KEGG: D01114
MeSH: ethylenediamine
PubChem CID: 3301
RTECS number: KH8575000
UNII: 60V9STC53F
UN number: 1604
CompTox Dashboard (EPA): DTXSID5021881
InChIInChI=1S/C2H8N2/c3-1-2-4/h1-4H2
Key: PIICEJLVQHRZGT-UHFFFAOYSA-N
SMILES: NCCN

Synonyms: 1,2-Diaminoethane
Linear Formula: NH2CH2CH2NH2
CAS Number: 107-15-3
Molecular Weight: 60.10
EC Number: 203-468-6

CAS number: 107-15-3
EC index number: 612-006-00-6
EC number: 203-468-6
Hill Formula: C₂H₈N₂
Chemical formula: H₂NCH₂CH₂NH₂
Molar Mass: 60.10 g/mol
HS Code: 2921 21 00

Properties of Ethylenediamine:
Chemical formula: C2H8N2
Molar mass: 60.100 g·mol−1
Appearance: Colorless liquid[3]
Odor: Ammoniacal[3]
Density: 0.90 g/cm3[3]
Melting point: 8 °C (46 °F; 281 K)[3]
Boiling point: 116 °C (241 °F; 389 K)[3]
Solubility in water: miscible
log P: −2.057
Vapor pressure: 1.3 kPa (at 20 °C)
Henry's law constant (kH): 5.8 mol Pa−1 kg−1
Magnetic susceptibility (χ):
-46.26·10−6 cm3/mol
-76.2·10−6 cm3/mol (HCl salt)
Refractive index (nD): 1.4565

Density: 0.897 g/cm3 (20 °C)
Explosion limit: 2 - 17 %(V)
Flash point: 38 °C
Ignition temperature: 405 °C
Melting Point: 11.1 °C
pH value: 12.2 (100 g/l, H₂O, 20 °C)
Vapor pressure: 12 hPa (20 °C)

Formula: C2H8N2
Formula mass: 60.10
Melting point, °C: 8.5
Boiling point, °C: 117
Vapor pressure, mmHg: 16 (25 C)
Vapor density (air=1): 2.07
Saturation Concentration: 1.3% at 20 C
Evaporization number: 0.91 (butyl acetate = 1)
Critical temperature: 340
Critical pressure: 66.19
Density: 0.898 g/cm3 (20 C)
Solubility in water: Miscible
Viscosity: 1.54 cp (25 C)
Surface tension: 40.77 g/s2 (20 C)
Refractive index: 1.454 (20 C)
Dipole moment: 1.83 D (25 C)
Dielectric constant: 16 (18 C)
pKa/pKb: 4.11 (pKb)
Partition coefficient, pKow: -2.04
Heat of fusion: 19.3 kJ/mol
Heat of vaporization: 46.9 kJ/mol
Heat of combustion: -1890 kJ/mol

Molecular Weight: 60.10
XLogP3: -2
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 1
Exact Mass: 60.068748264
Monoisotopic Mass: 60.068748264
Topological Polar Surface Area: 52 Ų
Heavy Atom Count: 4
Complexity: 6
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Ethylenediamine:
Color according to color reference solution Ph.Eur.: colorless liquid
Assay (GC, area%): ≥ 99.0 % (a/a)
Water (GC, area%): ≤ 1.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.896 - 0.898
Identity (IR): passes test

Melting Point: >300.0°C
Color: White
pH: 3.9 to 5 (1% aq. soln.)
Assay Percent Range: 98+%
Infrared Spectrum: Authentic
Linear Formula: H2NCH2CH2NH2·2HCl
Beilstein: 04, 230
Packaging: Plastic bottle
Merck Index: 15, 3849
Quantity: 100 g
Solubility Information: (1% in water) Clear colorless
IUPAC Name: ethane-1,2-diamine;dihydrochloride
Formula Weight: 133.04
Percent Purity: 98+%
Physical Form: Crystalline Powder
Chemical Name or Material: Ethylenediamine dihydrochloride, 98+%

Thermochemistry of Ethylenediamine:
Heat capacity (C): 172.59 J K−1 mol−1
Std molar entropy (S⦵298): 202.42 J K−1 mol−1
Std enthalpy of formation (ΔfH⦵298): −63.55–−62.47 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): −1.8678–−1.8668 MJ mol−1

Related compounds of Ethylenediamine:
Ethylamine
Ethylenedinitramine

Related alkanamines:
1,2-Diaminopropane
1,3-Diaminopropane

Names of Ethylenediamine:

Regulatory process names:
1,2-Diamino-ethaan
1,2-Diamino-ethano
1,2-Diaminoaethan
1,2-Diaminoethane
1,2-diaminoethane
1,2-Ethanediamine
1,2-Ethylenediamine
Aethaldiamin
Aethylenediamin
Algicode 106L
Amerstat 274
beta-Aminoethylamine
Dimethylenediamine
Edamine
Ethyleendiamine
Ethylendiamine
Ethylenediamine
ETHYLENEDIAMINE
ethylenediamine
Ethylenediamine
EDA
ethylenediamine; 1,2-diaminoethane

Translated names:
1,2 diaminoetaani (fi)
1,2-Diamino-ethan (de)
1,2-diaminoetaan (et)
1,2-diaminoetan (hr)
1,2-diaminoetan (no)
1,2-diaminoetan (pl)
1,2-diaminoetan (ro)
1,2-diaminoetan (sl)
1,2-diaminoetan (sv)
1,2-diaminoetanas (lt)
1,2-diaminoetán (hu)
1,2-diaminoetāns (lv)
1,2-диаминоетан (bg)
etano-1,2-diamina (pl)
ethan-1,2-diamin (cs)
ethyleendiamine (nl)
ethylendiamin (cs)
ethylendiamin (da)
Ethylendiamin (de)
etilen-diamina (ro)
etilendiamin (hr)
etilendiamin (sl)
etilendiamina (es)
etilendiamina (it)
etilendiaminas (lt)
etilenodiamina (pt)
etilén-diamin (hu)
etilēndiamīns (lv)
etyleenidiamiini (fi)
etylendiamin (no)
etylendiamin (sv)
etylenodiamina (pl)
etyléndiamín (sk)
etán-1,2-diamín (sk)
Etüleendiamiin (et)
éthylènediamine;1,2-diaminoéthane (fr)
αιθυλενοδιαμίν (el)
етилендиамин (bg)

CAS name:
1,2-Ethanediamine

IUPAC names:
1,2,-Diaminoethane
1,2-Diaminoethane
1,2-diaminoethane
1,2-Diaminoethane , 1,2-Ethylenediamine , 1,4-Diazabutane , Dimethylenediamine
1,2-Ethanediamine
Diaminoethane
Ethane-1,2-diamine
ethane-1,2-diamine
ethane-1,2-diamine
Ethylendiamin
ethylene diamine
Ethylene diamine
ethylene diamine
Ethylenediamine
ethylenediamine
Ethylenediamine
ethylenediamine 1,2-diaminoethane
Ethylenediamine Anhydrous
ethylenediamine; 1,2-diaminoethane

Preferred IUPAC name:
Ethane-1,2-diamine

Trade names:
Bruggolen P22
EDA
Ethylenediamine
ETHYLENEDIAMINE (EDA)
ETHYLENEDIAMINE.
Ethylenediamine.

Other names:
Edamine,
1,2-Diaminoethane,
'en' when a ligand

Synonyms of Ethylenediamine:
ethylenediamine
Ethane-1,2-diamine
107-15-3
1,2-Ethanediamine
1,2-Diaminoethane
Ethylene diamine
Ethylendiamine
edamine
Dimethylenediamine
1,2-Ethylenediamine
Aethaldiamin
Aethylenediamin
Ethyleendiamine
Ethylene-diamine
beta-Aminoethylamine
1,2-Diaminoaethan
Algicode 106L
Amerstat 274
1,2-Diamino-ethaan
1,2-Diamino-ethano
Ethylenediamine [JAN]
NCI-C60402
Edamine [INN]
ETHYLENEDIAMINE ANHYDROUS
CHEBI:30347
CHEMBL816
H2NCH2CH2NH2
ETHANE,1,2-DIAMINO
60V9STC53F
27308-78-7
2-Aminoethylammonium chloride
1, 2-Diaminoethane
NCGC00091527-01
1,2-diaminoethane phase II
EN
1,2-diaminoethane phase I beta
Aethaldiamin [German]
Caswell No. 437
1,2-diaminoethane phase I alpha
Ethyleendiamine [Dutch]
Aethylenediamin [German]
Ethylene-diamine [French]
Ethane-1,2-diammonium bromide
CAS-107-15-3
Ethylenediamine, ReagentPlus(R), >=99%
1,2-Diaminoaethan [German]
1,2-Diamino-ethaan [Dutch]
CCRIS 5224
HSDB 535
1,2-Diamino-ethano [Italian]
Aminophylline Injection
EINECS 203-468-6
UN1604
EPA Pesticide Chemical Code 004205
Ethylenediamine [USP:JAN]
BRN 0605263
UNII-60V9STC53F
ethylenediarnine
AI3-24231
2-aminoethylamine
ethylene di amine
1,4-diazabutane
1,2-diaminoethan
ethylene - diamine
EDN
1,2-ethylendiamine
MFCD00008204
1,2-diamino-ethane
ethane 1,2-diamine
N,N'-ethylenediamine
Ethylenediamine, 8CI
1,2-ethylene diamine
1,2-ethylene-diamine
Ethylenediamine [UN1604] [Corrosive]
.beta.-Aminoethylamine
ethane-1, 2-diamine
N,N'-ethylene diamine
Ethylenediamine, BioXtra
Epitope ID:117724
EC 203-468-6
ETHYLENEDIAMINE [II]
ETHYLENEDIAMINE [MI]
4-04-00-01166 (Beilstein Handbook Reference)
Ethylenediamine (USP/JP15)
Ethylenediamine (USP/JP17)
ETHYLENEDIAMINE [HSDB]
ETHYLENEDIAMINE [INCI]
BDBM7972
NH2(CH2)2NH2
ETHYLENEDIAMINE [MART.]
DTXSID5021881
ETHYLENEDIAMINE [WHO-DD]
624-59-9 (di-hydrobromide)
333-18-6 (di-hydrochloride)
5700-49-2 (di-hydriodide)
Ethylenediamine, analytical standard
STR00309
Tox21_111145
Tox21_201202
STL264241
ZINC37253587
ETHYLENEDIAMINE [EP MONOGRAPH]
AKOS000118850
DB14189
ETHYLENEDIAMINE [USP MONOGRAPH]
UN 1604
Ethylenediamine, for synthesis, 99.0%
NCGC00091527-02
NCGC00258754-01
BP-20367
Ethylenediamine [UN1604] [Corrosive]
E0077
E0081
EN300-19398
D01114
Ethylenediamine, SAJ special grade, >=99.0%
Ethylenediamine, meets USP testing specifications
Ethylenediamine, Vetec(TM) reagent grade, >=98%
Q411362
J-001723
Ethylenediamine, purified by redistillation, >=99.5%
TIZANIDINE HYDROCHLORIDE IMPURITY H [EP IMPURITY]
Z104473714
Ethylenediamine, puriss. p.a., absolute, >=99.5% (GC)
QuadraPure(R) AEA, 100-400 mum particle size, extent of labeling: 1.3 mmol/g loading, 1 % cross-linked with divinylbenzene
Ethylenediamine [JAN] [Wiki]
1,2-diamino ethane
1,2-DIAMINOETHANE
1,2-Ethandiamin [German] [ACD/IUPAC Name]
1,2-Ethanediamine [ACD/Index Name] [ACD/IUPAC Name]
1,2-Éthanediamine [French] [ACD/IUPAC Name]
1,2-ethylenediamine
107-15-3 [RN]
203-468-6 [EINECS]
605263 [Beilstein]
edamina [Spanish] [INN]
edamine [INN]
édamine [French] [INN]
edaminum (R) [Latin] [INN]
ethane-1,2-diamine
ethylene diamine
MFCD00008204 [MDL number]
эдамин [Russian] [INN]
乙二胺 [Chinese] [INN]
1,2-Diamino-ethaan [Dutch]
1,2-Diaminoethane, 1,2-Ethanediamine
1,2-Diamino-ethano [Italian]
1,4-DIAZABUTANE
2-aminoethynylamine
4-04-00-01166 [Beilstein]
8030-24-8 secondary RN [RN]
Aethaldiamin [German]
Aethylenediamin [German]
Amerstat 274
Diaminoethane
Dimethylenediamine
EDA (ethylenediamine)
EDN
EPI-DA (ethylenediamine)
ETHANE,1,2-DIAMINO
Ethyleendiamine [Dutch]
Ethylendiamine
Ethylene-d4 Diamine
Ethylene-diamine [French]
Ethylenediaminemissing
ethyne-1,2-diamine
β-Aminoethylamine
β-Aminoethylamine
ETHYLENEDIAMINE
Ethylenediamine appears as a clear colorless liquid with an ammonia-like odor.
Ethylenediamine is an alkane-alpha,omega-diamine in which the alkane is ethane.
Ethylenediamine derives from a hydride of an ethane.


CAS Number: 107-15-3
EC Number: 203-468-6
Molecular Formula: C2H8N2 or H2NCH2CH2NH2 or NH2CH2CH2NH2


Ethylenediamine's Flash point is 91 °F and a melting point of 47 °F.
Ethylenediamine's Vapors are heavier than air.
Ethylenediamine's density is 7.5 lb / gal.


Ethylenediamine is an alkane-alpha,omega-diamine in which the alkane is ethane.
Ethylenediamine has a role as a GABA agonist.
Ethylenediamine derives from a hydride of an ethane.


Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products.
Sensitivity to ethylenediamine may be identified with a clinical patch test.
Ethylenediamine (abbreviated as en when a ligand) is the organic compound with the formula C2H4(NH2)2.


This colorless liquid, Ethylenediamine, with an ammonia-like odor is a basic amine.
Ethylenediamine is a widely used building block in chemical synthesis, with approximately 500,000 tonnes produced in 1998.
Ethylenediamine is the first member of the so-called polyethylene amines.


Ethylenediamine dihydrochloride is a glycol ether that has been used as a solvent and plasticizer.
Ethylenediamine has the ability to convert nitrite ions into nitrous acid, which is an important reaction in the formation of DNA.
Ethylenediamine has been studied for its potential use in transfection experiments and structural analysis.


Ethylenediamine is also an ingredient of aminophylline, a xanthine bronchodilator used in the treatment of asthma and other respiratory problems.
Other medications where Ethylenediamine or its derivatives are found include some antihistamines and anti-nausea agents.
Ethylenediamine is thick, colorless to light-yellowish liquid with an ammonia-like odor, hygroscopic, lachrymator.


Ethylenediamine is the organic compound with the formula C2H4(NH2)2.
This colorless liquid, Ethylenediamine, with an ammonia-like odor is a strongly basic amine.
Ethylenediamine is a widely used building block in chemical synthesis, with approximately 500,000,000 kg being produced in 1998.


Ethylenediamine is the ethyleneamine with the lowest molecular weight.
Ethylenediamine contains two primary amine groups and is a colorless liquid.
Ethylenediamine is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 tonnes per annum.



USES and APPLICATIONS of ETHYLENEDIAMINE:
Ethylenediamine is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Release to the environment of Ethylenediamine can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release.


Ethylenediamine can be found in products with material based on: wood (e.g. floors, furniture, toys).
Ethylenediamine is used in the following products: adhesives and sealants, coating products, pH regulators and water treatment products, fillers, putties, plasters, modelling clay and water treatment chemicals.


Ethylenediamine is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment, health services and scientific research and development.
Ethylenediamine is used in the following products: fuels.


Other release to the environment of Ethylenediamine is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Ethylenediamine has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of Ethylenediamine can occur from industrial use: formulation of mixtures.
Ethylenediamine is used in the following products: pH regulators and water treatment products, adhesives and sealants, coating products, heat transfer fluids, hydraulic fluids and polymers.


Ethylenediamine has an industrial use resulting in manufacture of another substance (use of intermediates).
Ethylenediamine is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Ethylenediamine is used for the manufacture of: chemicals.


Release to the environment of Ethylenediamine can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture, in processing aids at industrial sites, of substances in closed systems with minimal release, in the production of articles and as processing aid.


Release to the environment of Ethylenediamine can occur from industrial use: manufacturing of the substance.
Ethylenediamine is used in large quantities for production of many industrial chemicals.
Ethylenediamine forms derivatives with carboxylic acids (including fatty acids), nitriles, alcohols (at elevated temperatures), alkylating agents, carbon disulfide, and aldehydes and ketones.


Because of its bifunctional nature, having two amines, Ethylenediamine readily forms heterocycles such as imidazolidines.
Ethylenediamine is used to make other chemicals and as a fungicide.
Ethylenediamine is also used as an excipient in many pharmacological preparations such as creams.


Notably, ethylenediamine is a contact sensitizer capable of producing local and generalized reactions.
Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products.
Ethylenediamine is also used as an excipient in many pharmacological preparations such as creams.


Notably, Ethylenediamine is a contact sensitizer capable of producing local and generalized reactions.
Sensitivity to Ethylenediamine may be identified with a clinical patch test.
Ethylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.


Ethylenediamine is used mainly as a building block for crop protection products, in the synthesis of chelating agents and for low-temperature-active bleaching agents.
The many other applications of Ethylenediamine include polyamides, lubricants, fuel additives and textiles.
Ethylenediamine is used as a building block for the synthesis of bleach activators, chelates and crop protection products.


Furthermore Ethylenediamine is used as an intermediate in applications like corrosion inhibitors, polyamide resins and lubricants/fuel additives.
Chain extender in the production of poyurethane resin for the water PU Dispersion (PUD).
Products derived from Ethylenediamine are frequently used for bleach activators and chelates in detergents and for fungicides in crop protection area.


Ethylenediamine is used as a solvent, it is miscible with polar solvents and is used to solubilize proteins such as albumins and casein.
Ethylenediamine is also used in certain electroplating baths.
Ethylenediamine is used as a corrosion inhibitor in paints and coolants.


Ethylenediamine is added to animal feeds as a source of iodide.
Ethylenediamine is used as chemicals for color photography developing, binders, adhesives, fabric softeners, curing agents for epoxies, and dyes.
Ethylenediamine is used as a compound to sensitize nitromethane into an explosive.


This mixture was used at Picatinny Arsenal during WWII, giving the nitromethane and ethylenediamine mixture the nickname PLX, or Picatinny Liquid Explosive.
Ethylenediamine is commonly used as an intermediate to produce detergents, chelates, textile auxiliaries, agrochemicals and polyamides.
Uses of Ethylenediamine: Solvent for casein, albumin, shellac, and sulfur, emulsifier, stabilizing rubber latex, as inhibitor in antifreeze solutions, in textile lubricants, pharmaceutic aid (aminophylline injection stabilizer).


Ethylenediamine dihydrochloride can also be used to study phase transitions at different temperatures, as well as its electrochemical properties.
Ethylenediamine is used as a solvent, it is miscible with polar solvents and is used to solubilize proteins such as albumins and casein.
Ethylenediamine is also used in certain electroplating baths.


Ethylenediamine is used as a corrosion inhibitor in paints and coolants.
Ethylenediamine is added to animal feeds as a source of iodide.
Ethylenediamine is used as chemical for color photography developing, binders, adhesives, fabric softeners, curing agents for epoxys, and dyes.


Ethylenediamine is used in large quantities for production of many industrial chemicals.
Ethylenediamine forms derivatives with carboxylic acids (including fatty acids), nitriles, alcohols (at elevated temperatures), alkylating agents, carbon disulfide, and aldehydes and ketones.
Because of its bifunctional nature, having two amines, Ethylenediamine readily forms heterocycles such as imidazolidines.


-Pharmaceutical ingredient:
Ethylenediamine is an ingredient in the common bronchodilator drug aminophylline, where it serves to solubilize the active ingredient theophylline.
Ethylenediamine has also been used in dermatologic preparations, but has been removed from some because of causing contact dermatitis.
When used as a pharmaceutical excipient, after oral administration Ethylenediamine's bioavailability is about 0.34, due to a substantial first-pass effect.
Less than 20% is eliminated by renal excretion.
Ethylenediamine-derived antihistamines are the oldest of the five classes of first-generation antihistamines, beginning with piperoxan aka benodain, discovered in 1933 at the Pasteur Institute in France, and also including mepyramine, tripelennamine, and antazoline.
The other classes are derivatives of ethanolamine, alkylamine, piperazine, and others (primarily tricyclic and tetracyclic compounds related to phenothiazines, tricyclic antidepressants, as well as the cyproheptadine-phenindamine family)


-Role in polymers:
Ethylenediamine, because it contains two amine groups, is a widely used precursor to various polymers.
Condensates derived from formaldehyde are plasticizers.
Ethylenediamine is widely used in the production of polyurethane fibers.
The PAMAM class of dendrimers are derived from ethylenediamine.


-Uses of Ethylenediamine:
*Corrosion inhibitors
*Wet-strength resins
*Fabric softeners
*Epoxy curing agents
*Polyamide resins
*Fuel additives
*Lube oil additives
*Asphalt additives


-Uses of Ethylenediamine:
*Ore flotation
*Corrosion inhibitors
*Ore flotation
*Asphalt
*Additives
*Corrosion inhibitors
*Epoxy curing agents
*Hydrocarbon purification
*Lube oil & fuel additives
*Mineral processing aids
*Polyamide resins


-Uses of Ethylenediamine:
*Surfactants
*Textile additives-paper wet-strength resins
*Fabric softeners
*Surfactants
*Coatings
*Urethanes
*Fuel additives
*Chemical intermediates
*Epoxy curing agents
*Lube oils
*Wet strength resins


-Uses of Ethylenediamine:
*Bleach Activator
*Chelating Agents
*Epoxy Curing Agents
*Fungicides
*Industrial Surfactants
*Lube, Oil and Fuel Additives
*Phosphonates
*Plastic Lubricants
*Polyamide Resins
*Urethane Chemicals
*Other applications



BENEFITS OF ETHYLENEDIAMINE:
*Consistent and predictable reaction products
*Easily derivatized
*Low vapor pressure
*High viscosity
*Low environmental impact
*Suitable for harsh conditions
*Low sensitivity
*Versatile



MARKETS OF ETHYLENEDIAMINE:
*Aerospace, Marine and Automotive
*Agriculture
*Construction and Housing
*Consumer Electronics
*Household Detergents and Cleaners
*Human and Animal Health Care
*Food
*Industrial Cleaners and Preservants
*Mining
*Personal Care
*Pulp and Paper
*Road Construction
*Textiles and Sports



BENEFITS OF ETHYLENEDIAMINE:
*Consistent and predictable reaction products
*Easily derivatized
*Low vapor pressure
*High viscosity
*Low environmental impact
*Suitable for harsh conditions
*Low sensitivity
*Versatile



SYNTHESIS OF ETHYLENEDIAMINE:
Ethylenediamine is manufactured by reacting ammonia and 1,2-dichloroethane.
The reaction yields the mixture of ethylenediamine and the linear polyamines.
A simplified equation would be:
ClCH2CH2Cl + 4 NH3 → H2NCH2CH2NH2 + 2 NH4Cl



WHAT IS ETHYLENEDIAMINE AND WHERE IS ETHYLENEDIAMINE FOUND?
Ethylenediamine is a potent sensitiser used in topical medications, particularly antibiotic/steroid creams for its chemical stabilizing properties.
Ethylenediamine has been commonly found that individuals who show a positive patch test reaction to ethylenediamine have used, a popular broad-spectrum antifungal/steroid cream, or one of its generic preparations.
Ethylenediamine is not used in ointment preparations and is rarely found in cosmetics and toiletries.



SYNTHESIS OF ETHYLENEDIAMINE:
Ethylenediamine is produced industrially by treating 1,2-dichloroethane with ammonia under pressure at 180 °C in an aqueous medium.
In this reaction hydrogen chloride is generated, which forms a salt with the amine.
The amine is liberated by addition of sodium hydroxide and can then be recovered by rectification.
Diethylenetriamine (DETA) and triethylenetetramine (TETA) are formed as by-products.

Another industrial route to ethylenediamine involves the reaction of ethanolamine and ammonia.
This process involves passing the gaseous reactants over a bed of nickel heterogeneous catalysts.
Ethylenediamine can be produced in the lab by the reaction of ethylene glycol and urea.
Ethylenediamine can be purified by treatment with sodium hydroxide to remove water followed by distillation.



COORDINATION CHEMISTRY OF ETHYLENEDIAMINE:
Ethylenediamine is a well-known bidentate chelating ligand for coordination compounds, with the two nitrogen atoms donating their lone pairs of electrons when ethylenediamine acts as a ligand.

Ethylenediamine is often abbreviated "en" in inorganic chemistry.
The complex [Co(ethylenediamine)3]3+ is an archetypical chiral tris-chelate complex.
The salen ligands, some of which are used in catalysis, are derived from the condensation of salicylaldehydes and ethylenediamine.

-Related ligands:
Related derivatives of ethylenediamine include ethylenediaminetetraacetic acid (EDTA), tetramethylethylenediamine (TMEDA), and tetraethylethylenediamine (TEEDA).
Chiral analogs of ethylenediamine include 1,2-diaminopropane and trans-diaminocyclohexane.



PRECURSOR TO PHARMACEUTICALS AND AGRICHEMICALS:
Numerous bio-active compounds contain the N-CH2-CH2-N linkage, including aminophylline and some antihistamines. Salts of ethylenebisdithiocarbamate are commercially significant fungicides under the brandnames Maneb, Mancozeb, Zineb, and Metiram. Some imidazoline-containing fungicides are derived from ethylenediamine.



PRECURSOR TO CHELATING AGENTS:
The most prominent derivative of Ethylenediamine is EDTA, which is derived from ethylenediamine via a Strecker synthesis involving cyanide and formaldehyde. Hydroxyethylethyelenediamine is another commercially significant chelating agent.
The salen ligands, derived from the condensation of salicaldehydes and ethylenediamine, are popular chelating agents in the research laboratory although not commercially significant.



TETRAACETYLETHYLENEDIAMINE:
The bleaching activator tetraacetylethylenediamine is generated from ethylenediamine.
The derivative N,N-ethylenebis(stearamide) (EBS) is a commercially significant mold-release agent and a surfactant in gasoline and motor oil.



ROLE IN POLYMERS:
Ethylenediamine, by virtue of its bifunctionality (i.e. it contains two reactive amines) is widely used in diverse polyester formulations. Condensates derived from formaldehyde are plasticizers. It is widely used in the production of polyurethane fibers. The PAMAM class of dendrimers are derived from ethylenediamine.



ETHYLENEAMINES:
Ethylenediamine is the first member of the so-called polyethylene amines, other members being:
Diethylenetriamine, abbreviated dien or DETA, (H2N-CH2CH2-NH-CH2CH2-NH2, an analog of diethylene glycol)
Triethylenetetramine, abbreviated trien or TETA, (H2N-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH2)

Tetraethylenepentamine, abbreviated TEPA, (H2N-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH2),
Pentaethylenehexamine, abbreviated PEHA, (H2N-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH2), up to polyethylene amine. Similarly piperazine is an analogue of dioxane.

Related diamines:
In terms of quantities produced, ethylenediamine is the most significant diamine (aside from diaminohexane, which is a precursor to Nylon 66).
Related derivatives of ethylenediamine include tetramethylethylenediamine, abbreviated (TMEDA), (CH3)2N-CH2CH2-N(CH3)2 and tetraethylethylenediamine, abbreviated (TEEDA), (C2H5)2N-CH2CH2-N(C2H5)2



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENEDIAMINE:
Molecular Weight: 60.10
XLogP3: -2
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 1
Exact Mass: 60.068748264
Monoisotopic Mass: 60.068748264
Topological Polar Surface Area: 52 Ų
Heavy Atom Count: 4
Formal Charge: 0
Complexity: 6
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Flash point: 34 °C (93 °F; 307 K)
Autoignition temperature: 385 °C (725 °F; 658 K)
Explosive limits: 2.7–16%
Heat capacity (C): 172.59 J K−1 mol−1
Std molar entropy (S⦵298): 202.42 J K−1 mol−1
Std enthalpy of formation (ΔfH⦵298): −63.55–−62.47 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): −1.8678–−1.8668 MJ mol−1
Chemical formula: C2H8N2
Molar mass: 60.100 g·mol−1
Appearance: Colorless liquid
Odor: Ammoniacal
Density: 0.90 g/cm3
Melting point: 8 °C (46 °F; 281 K)
Boiling point: 116 °C (241 °F; 389 K)
Solubility in water: miscible
log P: −2.057
Vapor pressure: 1.3 kPa (at 20 °C)
Henry's law constant (kH): 5.8 mol Pa−1 kg−1
Magnetic susceptibility (χ): -46.26·10−6 cm3/mol
-76.2·10−6 cm3/mol (HCl salt)
Refractive index (nD): 1.4565

Formula: C2H8N2
Formula mass: 60.10
Melting point, °C: 8.5
Boiling point, °C: 117
Vapor pressure, mmHg: 16 (25 C)
Vapor density (air=1): 2.07
Saturation Concentration: 1.3% at 20 C
Evaporization number: 0.91 (butyl acetate = 1)
Critical temperature: 340
Critical pressure: 66.19
Density: 0.898 g/cm3 (20 C)
Solubility in water: Miscible
Viscosity: 1.54 cp (25 C)
Surface tension: 40.77 g/s2 (20 C)
Refractive index: 1.454 (20 C)
Dipole moment: 1.83 D (25 C)
Dielectric constant: 16 (18 C)

pKa/pKb: 4.11 (pKb)
Partition coefficient, pKow: -2.04
Heat of fusion: 19.3 kJ/mol
Heat of vaporization: 46.9 kJ/mol
Heat of combustion: -1890 kJ/mol
Physical state: liquid
Color: colorless
Odor: amine-like
Melting point/freezing point
Melting point/range: 8,5 °C
Initial boiling point and boiling range: 118 °C
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 17 %(V)
Lower explosion limit: 2 %(V)
Flash point: 38 °C - closed cup

Autoignition temperature: 405 °C
Decomposition temperature: > 120 °C
pH: 12,2 at 100 g/l at 20 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 1,265 - 1,725 mPa.s at 25 °C
Water solubility 1.000 g/l - miscible
Partition coefficient: n-octanol/water:
log Pow: -2,04 - Bioaccumulation is not expected., (Lit.)
Vapor pressure 12 hPa at 20 °C
Density 0,899 g/mL at 25 °C
Relative density No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none

Other safety information:
Relative vapor density: 2,07 - (Air = 1.0)
CAS number: 107-15-3
EC index number: 612-006-00-6
EC number: 203-468-6
Hill Formula: C₂H₈N₂
Chemical formula: H₂NCH₂CH₂NH₂
Molar Mass: 60.10 g/mol
HS Code: 2921 21 00
Density: 0.897 g/cm3 (20 °C)
Explosion limit: 2 - 17 %(V)
Flash point: 38 °C
Ignition temperature: 405 °C
Melting Point: 11.1 °C
pH value: 12.2 (100 g/l, H₂O, 20 °C)
Vapor pressure: 12 hPa (20 °C)

Physical description: Colorless, viscous liquid with an ammonia-like odor.
Boiling point: 241°F
Molecular weight: 60.1
Freezing point/melting point: 47°F
Vapor pressure: 11 mmHg
Flash point: 93°F
Vapor density: 2.07
Specific gravity: 0.91
Ionization potential: 8.60 eV
Lower explosive limit (LEL): 4.2%
Upper explosive limit (UEL): 14.4%
NFPA health rating: 3
NFPA fire rating: 2
NFPA reactivity rating: 0
NFPA special instruction: 0



FIRST AID MEASURES of ETHYLENEDIAMINE:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most), avoid vomiting.
Call a physician immediately.
Do not attempt to neutralise.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ETHYLENEDIAMINE:
-Personal precautions, protective equipment and emergency procedures:
*Advice for non-emergency personnel:
Ensure adequate ventilation.
Evacuate the danger area, observe emergency procedures, consult an expert.
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ETHYLENEDIAMINE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENEDIAMINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 240 min
*Body Protection:
Flame retardant antistatic protective clothing.
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ETHYLENEDIAMINE:
-Precautions for safe handling:
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Handle and store under inert gas.



STABILITY and REACTIVITY of ETHYLENEDIAMINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
Absorbs carbon dioxide (CO2) from air.
-Possibility of hazardous reactions:
No data available



SYNONYMS:
ethylenediamine
Ethane-1,2-diamine
107-15-3
1,2-Ethanediamine
1,2-Diaminoethane
Ethylene diamine
Ethylendiamine
edamine
Dimethylenediamine
1,2-Ethylenediamine
Aethaldiamin
Aethylenediamin
Ethyleendiamine
Ethylene-diamine
beta-Aminoethylamine
1,2-Diaminoaethan
Algicode 106L
Amerstat 274
1,2-Diamino-ethaan
1,2-Diamino-ethano
Ethylenediamine [JAN]
NCI-C60402
Edamine [INN]
ETHYLENEDIAMINE ANHYDROUS
CHEBI:30347
CHEMBL816
H2NCH2CH2NH2
ETHANE,1,2-DIAMINO
60V9STC53F
27308-78-7
DTXSID5021881
2-Aminoethylammonium chloride
1, 2-Diaminoethane
NCGC00091527-01
1,2-diaminoethane phase II
EN
DTXCID501881
1,2-diaminoethane phase I beta
Aethaldiamin [German]
Caswell No. 437
1,2-diaminoethane phase I alpha
Ethane-1,2-diammonium bromide
CAS-107-15-3
Ethylenediamine, ReagentPlus(R), >=99%
CCRIS 5224
HSDB 535
Aminophylline Injection
EINECS 203-468-6
UN1604
EPA Pesticide Chemical Code 004205
Ethylenediamine [USP:JAN]
BRN 0605263
UNII-60V9STC53F
ethylenediarnine
AI3-24231
2-aminoethylamine
ethylene di amine
1,4-diazabutane
1,2-diaminoethan
ethylene - diamine
EDN
1,2-ethylendiamine
MFCD00008204
1,2-diamino-ethane
ethane 1,2-diamine
N,N'-ethylenediamine
Ethylenediamine, 8CI
1,2-ethylene diamine
1,2-ethylene-diamine
Ethylenediamine [UN1604]
.beta.-Aminoethylamine
ethane-1, 2-diamine
N,N'-ethylene diamine
Ethylenediamine, BioXtra
Epitope ID:117724
EC 203-468-6
ETHYLENEDIAMINE [II]
ETHYLENEDIAMINE [MI]
4-04-00-01166 (Beilstein Handbook Reference)
Ethylenediamine (USP/JP15)
Ethylenediamine (USP/JP17)
ETHYLENEDIAMINE [HSDB]
ETHYLENEDIAMINE [INCI]
BDBM7972
NH2(CH2)2NH2
ETHYLENEDIAMINE [MART.]
ETHYLENEDIAMINE [WHO-DD]
624-59-9 (di-hydrobromide)
333-18-6 (di-hydrochloride)
5700-49-2 (di-hydriodide)
Ethylenediamine, analytical standard
STR00309
Tox21_111145
Tox21_201202
STL264241
ZINC37253587
ETHYLENEDIAMINE [EP MONOGRAPH]
AKOS000118850
DB14189
ETHYLENEDIAMINE [USP MONOGRAPH]
UN 1604
Ethylenediamine, for synthesis, 99.0%
NCGC00091527-02
NCGC00258754-01
BP-20367
Ethylenediamine [UN1604]
E0077
E0081
EN300-19398
D01114
Ethylenediamine, SAJ special grade, >=99.0%
Ethylenediamine, meets USP testing specifications
Ethylenediamine, Vetec(TM) reagent grade, >=98%
Q411362
J-001723
Ethylenediamine, purified by redistillation, >=99.5%
TIZANIDINE HYDROCHLORIDE IMPURITY H [EP IMPURITY]
Z104473714
Ethylenediamine, puriss. p.a., absolute, >=99.5% (GC)
1.3 mmol/g loading, 1 % cross-linked with divinylbenzene
Ethane-1,2-diamine
Edamine
1,2-Diaminoethane
1,2-Diaminoethane
1,2-Ethanediamine
Ethylenediamine (anhydrous)
1,2-Ethanediamine
β-Aminoethylamine
Dimethylenediamine
Ethane-1,2-diamine
1,2-Diaminoethane
1,2-Ethylenediamine
H2NCH2CH2NH2
Aethaldiamin
Aethylenediamin
1,2-Diaminoaethan
1,2-Diamino-ethaan
1,2-Diamino-ethano
Ethyleendiamine
Ethylendiamine
NCI-C60402
UN 1604


ETHYLENEDIAMINE (EDA)

Ethylenediamine (EDA), also known as 1,2-diaminoethane, is an organic compound with the chemical formula C2H8N2.
Ethylenediamine (EDA) is a colorless liquid with an ammonia-like odor.
Ethylenediamine (EDA) is a simple diamine, meaning it contains two amino groups (-NH2) separated by two carbon atoms.

CAS Number: 107-15-3
EC Number: 203-468-6

Ethylenediamine, EDA, 1,2-diaminoethane, 1,2-ethanediamine, 1,2-Diaminoethane, Ethane-1,2-diamine, 1,2-Ethylenediamine, Aethaldiamine, 1,2-Diazaethane, Ethylamine, Diaminoethane, Ethylenediamin, Glycolamine, Ethane-1,2-diyldiamine, α,ω-Diaminoethane, H2NCH2CH2NH2, Dimethylethylenediamine, 1,2-Diaminethylethane, Ethyleneimine, N,N'-Bis(2-aminoethyl)ethane-1,2-diamine, Ethylene Diamine, H2N(CH2)2NH2, Ethylamine, Diaminoethylene, 1,2-Ethandiamine, 1,2-エチレンジアミン, Diaminethylethane



APPLICATIONS


Ethylenediamine (EDA) is commonly used as a chelating agent in the formulation of metal ion complexes for various industrial processes.
Ethylenediamine (EDA) is utilized in the production of chelating agents such as EDTA (ethylenediaminetetraacetic acid) and DTPA (diethylenetriaminepentaacetic acid).
Ethylenediamine (EDA) is employed in the purification of water by complexing with metal ions and removing them from solution.

Ethylenediamine (EDA) serves as a precursor for the synthesis of polyamines, which are used as curing agents in epoxy resins and polyurethane foams.
Ethylenediamine (EDA) is an essential component in the manufacture of fungicides, herbicides, and insecticides for agricultural applications.

Ethylenediamine (EDA) is used in the production of pharmaceuticals, including antihistamines, antifungal agents, and local anesthetics.
Ethylenediamine (EDA) is employed as a catalyst in the synthesis of specialty chemicals and pharmaceutical intermediates.

Ethylenediamine (EDA) serves as a raw material in the synthesis of polymers such as nylon, polyamides, and polyurethanes.
Ethylenediamine (EDA) is utilized in the preparation of adhesives, coatings, and sealants for various industrial applications.
Ethylenediamine (EDA) acts as a solvent in the extraction of natural products and in the formulation of specialty chemicals.

Ethylenediamine (EDA) is used in the textile industry for dyeing and printing processes due to its ability to form stable complexes with metal ions.
Ethylenediamine (EDA) serves as a corrosion inhibitor in metalworking fluids, protecting metal surfaces from oxidation and rust.

Ethylenediamine (EDA) is employed in the synthesis of surfactants and detergents for use in cleaning and personal care products.
Ethylenediamine (EDA) serves as a complexing agent in the formulation of metal plating baths for electroplating processes.
Ethylenediamine (EDA) is utilized in the production of fuel additives, lubricants, and hydraulic fluids to improve performance and stability.

Ethylenediamine (EDA) acts as a pH regulator and stabilizer in industrial processes such as paper manufacturing and wastewater treatment.
Ethylenediamine (EDA) is used in the synthesis of ion exchange resins for water softening and purification applications.

Ethylenediamine (EDA) serves as a reagent in analytical chemistry for the determination of metal ions and complexometric titrations.
Ethylenediamine (EDA) is employed in the synthesis of specialty chemicals used in the electronics industry for semiconductor manufacturing.
Ethylenediamine (EDA) serves as a catalyst in the production of polyurethane elastomers and foams for automotive and construction applications.

Ethylenediamine (EDA) is utilized in the production of rubber chemicals, antioxidants, and vulcanization accelerators.
Ethylenediamine (EDA) serves as a stabilizer and antioxidant in the formulation of polymers and plastics to prevent degradation during processing and storage.

Ethylenediamine (EDA) is used in the synthesis of adhesives and sealants for bonding substrates in construction and automotive applications.
Ethylenediamine (EDA) serves as a reagent in the production of dyes, pigments, and photographic chemicals for printing and imaging applications.
Ethylenediamine (EDA) is an important chemical intermediate with diverse applications in various industries, contributing to the development of innovative materials and products.

Ethylenediamine (EDA) is used in the synthesis of ion-exchange resins for chromatography and purification applications in analytical chemistry.
Ethylenediamine (EDA) serves as a complexing agent in the formulation of metal complexes used as catalysts in organic synthesis.
Ethylenediamine (EDA) is employed in the preparation of metal nanoparticles and nanocomposites for catalysis and material science applications.

Ethylenediamine (EDA) is used in the production of specialty chemicals such as corrosion inhibitors, antifoaming agents, and scale inhibitors for industrial processes.
Ethylenediamine (EDA) is utilized in the formulation of adhesives and sealants for bonding substrates in aerospace and marine applications.

Ethylenediamine (EDA) serves as a component in the synthesis of crosslinking agents for the modification of polymers and elastomers.
Ethylenediamine (EDA) is employed in the synthesis of specialty resins for coatings, inks, and varnishes for architectural and industrial applications.

Ethylenediamine (EDA) serves as a chemical intermediate in the production of flavors, fragrances, and pharmaceutical excipients.
Ethylenediamine (EDA) is used in the formulation of metalworking fluids for lubrication and cooling during machining processes.
Ethylenediamine (EDA) serves as a reagent in the production of specialty gases, including ethylenediamine dinitrate (EDDN) for explosives and propellants.

Ethylenediamine (EDA) is employed in the synthesis of cationic surfactants and softeners for use in fabric softeners and textile finishing agents.
Ethylenediamine (EDA) serves as a crosslinking agent in the production of rubber vulcanizates for tire manufacturing and automotive applications.
Ethylenediamine (EDA) is used in the formulation of antifreeze and coolant additives for automotive and industrial cooling systems.

Ethylenediamine (EDA) serves as a stabilizer and dispersant in the formulation of emulsions and suspensions for pharmaceutical and cosmetic applications.
Ethylenediamine (EDA) is employed in the production of specialty polymers such as polyamide-imides and polyethyleneimines for high-performance applications.
Ethylenediamine (EDA) serves as a reagent in the synthesis of urea-formaldehyde resins for use in wood adhesives and composite materials.

Ethylenediamine (EDA) is utilized in the formulation of cleaning agents and degreasers for industrial and household applications.
Ethylenediamine (EDA) serves as a catalyst in the production of polyols and isocyanates for the synthesis of polyurethane foams and coatings.

Ethylenediamine (EDA) is employed in the synthesis of pharmaceutical intermediates such as benzylpenicillin and ethylenediaminetetraacetonitrile.
Ethylenediamine (EDA) serves as a crosslinking agent in the production of dental materials such as impression compounds and denture adhesives.

Ethylenediamine (EDA) is used in the formulation of inkjet inks and toners for printing and imaging applications.
Ethylenediamine (EDA) serves as a reagent in the synthesis of specialty polymers such as polycarboxylates for water treatment and concrete additives.

Ethylenediamine (EDA) is employed in the formulation of deicing agents and antifreeze solutions for aircraft and runway maintenance.
Ethylenediamine (EDA) serves as a component in the synthesis of pharmaceutical active ingredients such as antiviral drugs and anticancer agents.
Ethylenediamine (EDA) is an essential chemical with diverse applications across various industries, contributing to the development of advanced materials, technologies, and products.



DESCRIPTION


Ethylenediamine (EDA), also known as 1,2-diaminoethane, is an organic compound with the chemical formula C2H8N2.
Ethylenediamine (EDA) is a colorless liquid with an ammonia-like odor.
Ethylenediamine (EDA) is a simple diamine, meaning it contains two amino groups (-NH2) separated by two carbon atoms.

Ethylenediamine (EDA) is primarily used as a building block in the production of various chemicals, including chelating agents, polyurethane resins, fuel additives, and pharmaceuticals.
Ethylenediamine (EDA) is a versatile compound with strong nucleophilic properties, making it useful in many chemical reactions.

Ethylenediamine (EDA) is a colorless, viscous liquid at room temperature.
Ethylenediamine (EDA) has a distinctive ammonia-like odor, which is characteristic of primary amines.

Ethylenediamine (EDA) is highly soluble in water, alcohol, and other polar solvents.
Ethylenediamine (EDA) is hygroscopic, meaning it readily absorbs moisture from the air.

Ethylenediamine has a boiling point of approximately 116°C and a melting point of about −8°C.
Ethylenediamine (EDA) is miscible with many organic solvents, making it useful in various chemical reactions.

Ethylenediamine (EDA) is commonly used as a chelating agent to bind metal ions in solution.
Ethylenediamine (EDA) forms stable complexes with transition metals such as copper, iron, and nickel.

Ethylenediamine (EDA) is a versatile building block in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals.
Ethylenediamine (EDA) serves as a precursor for the synthesis of polyamines and polyamides.
Ethylenediamine (EDA) can act as a ligand in coordination chemistry, forming coordination complexes with metal ions.

Ethylenediamine (EDA) is used in the production of polyurethane foams, resins, and coatings.
Ethylenediamine (EDA) is employed as a curing agent for epoxy resins, enhancing their mechanical properties.
In the petroleum industry, EDA is used as a selective solvent for the removal of hydrogen sulfide and carbon dioxide from natural gas streams.

Ethylenediamine (EDA) is also utilized in the purification of hydrocarbon streams and as a corrosion inhibitor.
Ethylenediamine (EDA) is employed as a stabilizer and pH adjuster in industrial processes such as metal plating and textile manufacturing.
Ethylenediamine (EDA) serves as a precursor for the synthesis of ethylenediaminetetraacetic acid (EDTA), a widely used chelating agent in analytical chemistry.

Ethylenediamine (EDA) is an important component in the production of herbicides, fungicides, and insecticides.
Ethylenediamine (EDA) exhibits strong nucleophilic properties, facilitating reactions such as alkylation, acylation, and reductive amination.
Ethylenediamine (EDA) is used in the preparation of specialty chemicals, surfactants, and detergents.

Ethylenediamine (EDA) plays a role in the synthesis of dyes, pigments, and photographic chemicals.
Ethylenediamine can react with acids to form ethylenediammonium salts, which are used as ion-exchange resins and in the production of fertilizers.

In the pharmaceutical industry, EDA is employed in the synthesis of antihistamines, local anesthetics, and antifungal agents.
Due to its alkaline nature, ethylenediamine can cause skin and eye irritation upon contact and should be handled with caution.
Ethylenediamine (EDA) is a versatile compound with diverse applications in various industries, from chemical manufacturing to pharmaceuticals and beyond.



PROPERTIES


Physical Properties:

Appearance: Clear, colorless liquid
Odor: Ammonia-like odor
Density: 0.899 g/cm³ (at 20°C)
Melting Point: −8.5°C
Boiling Point: 116.8°C
Flash Point: 36°C (closed cup)
Vapor Pressure: 7.4 mmHg (at 20°C)
Solubility in Water: Completely miscible
Vapor Density: 2.6 (air = 1)
Refractive Index: 1.455 (at 20°C)


Chemical Properties:

Chemical Formula: C2H8N2
Molecular Weight: 60.10 g/mol
Structure: Ethylenediamine consists of two amino groups (-NH2) separated by two carbon atoms (-CH2-CH2-).
Solubility: Soluble in water, alcohol, and polar solvents
pH: Basic (alkaline) in aqueous solution
Acidity/Basicity: Exhibits basic properties due to the presence of amino groups
Reactivity: Ethylenediamine is a strong nucleophile and can undergo reactions such as alkylation, acylation, and complex formation with metal ions.
Stability: Generally stable under normal conditions, but may degrade upon exposure to heat, light, or air.
Flammability: Flammable liquid, forms flammable vapor-air mixtures.
Corrosivity: Can cause corrosion to metals upon prolonged contact.
Toxicity: Ethylenediamine is toxic if ingested and can cause skin and eye irritation upon contact.
Biodegradability: Biodegradable under aerobic conditions, but persistence in the environment may vary.
Hazardous Polymerization: Does not occur under normal conditions.
Autoignition Temperature: 390°C
Explosive Limits: Lower Explosive Limit (LEL) - 3.3% (Volume), Upper Explosive Limit (UEL) - 15.7% (Volume)



FIRST AID


Inhalation:

If Ethylenediamine vapors are inhaled and respiratory irritation occurs, immediately move the affected person to fresh air.
Allow the individual to rest in a well-ventilated area and provide them with oxygen if breathing difficulties persist.
If the person is not breathing or shows signs of respiratory distress, administer artificial respiration. Seek medical attention promptly.
Keep the person warm and comfortable. Do not leave them unattended.


Skin Contact:

In case of skin contact with Ethylenediamine, immediately remove contaminated clothing and shoes.
Rinse the affected area with plenty of water for at least 15 minutes to remove any residual chemical.
Wash the skin thoroughly with mild soap and water to remove any remaining traces of Ethylenediamine.
If skin irritation, redness, or rash develops, seek medical advice promptly.
Do not apply ointments or creams to the affected area unless instructed by medical personnel.


Eye Contact:

If Ethylenediamine comes into contact with the eyes, immediately flush the eyes with gently flowing water for at least 15 minutes.
Hold the eyelids open to ensure thorough rinsing and remove any contact lenses if present and easily removable.
Seek immediate medical attention, even if the affected person does not experience immediate symptoms.
Do not rub the eyes, as this may exacerbate irritation and cause further damage.


Ingestion:

If Ethylenediamine is ingested accidentally and the person is conscious, rinse their mouth thoroughly with water and encourage them to drink water or milk to dilute the chemical.
Do not induce vomiting unless instructed to do so by medical personnel, especially if the individual is unconscious or experiencing convulsions.
Seek medical advice immediately, and provide the healthcare provider with information about the ingested substance, including its name, concentration, and the amount ingested.
Monitor the person for signs of gastrointestinal distress, such as nausea, vomiting, or abdominal pain, and seek medical attention promptly if symptoms worsen or persist.


General Precautions:

Always handle Ethylenediamine with care and wear appropriate personal protective equipment (PPE) such as gloves, goggles, and protective clothing to prevent skin and eye contact.
Avoid breathing in vapors or mists of Ethylenediamine. Use local exhaust ventilation or respiratory protection if necessary.
Keep containers tightly closed when not in use and store them in a cool, dry, well-ventilated area away from sources of heat, ignition, and incompatible substances.
In case of a spill, contain the area and prevent further release of the chemical into the environment. Clean up spills promptly using appropriate absorbent materials and dispose of waste according to local regulations.



HANDLING AND STORAGE


Handling:

When handling Ethylenediamine (EDA), wear appropriate personal protective equipment (PPE) including chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact.
Avoid breathing in vapors or mists of Ethylenediamine.
Use local exhaust ventilation or respiratory protection if necessary to control airborne exposure.
Ensure adequate ventilation in the work area to minimize the buildup of vapors or fumes. Use explosion-proof equipment in areas where flammable vapors may be present.
Prevent contact with incompatible materials such as strong acids, oxidizing agents, and alkalis, as they may react violently with Ethylenediamine and release hazardous gases.
Use caution when transferring or pouring Ethylenediamine to prevent spills and splashes. Use appropriate tools and equipment such as funnels or pumps to minimize contact with the chemical.
Keep containers tightly closed when not in use to prevent contamination and minimize exposure to air and moisture.
Avoid contact with skin, eyes, and clothing.
In case of contact, follow appropriate first aid measures and rinse thoroughly with water.
Do not eat, drink, or smoke while handling Ethylenediamine, and wash hands thoroughly after handling to prevent accidental ingestion.
Avoid prolonged or repeated exposure to Ethylenediamine, as it may cause skin irritation, sensitization, or allergic reactions in some individuals.
Handle Ethylenediamine with care to prevent spills, leaks, and releases into the environment.
Clean up spills promptly using appropriate absorbent materials and dispose of waste according to local regulations.


Storage:

Store Ethylenediamine in a cool, dry, well-ventilated area away from sources of heat, ignition, and direct sunlight.
Keep containers tightly closed and upright to prevent leakage or spills. Store larger quantities in suitable containers with secondary containment to contain spills.
Store Ethylenediamine away from incompatible materials such as strong acids, oxidizing agents, and alkalis to prevent reactions or contamination.
Ensure storage areas are equipped with appropriate firefighting equipment and spill containment materials in case of emergencies.
Follow local regulations and guidelines for the storage of chemicals, including any specific requirements for the storage of Ethylenediamine.
Keep storage areas clean and free from clutter to minimize the risk of spills and accidents.
Check containers regularly for signs of damage or deterioration and replace any damaged or compromised containers promptly.
Store Ethylenediamine in its original packaging or labeled containers to ensure proper identification and traceability.
Separate Ethylenediamine from incompatible materials by storing them in separate areas or using barriers to prevent contact.
Monitor storage conditions regularly to ensure compliance with safety guidelines and to prevent the buildup of hazardous conditions.

ETHYLENEDIAMINE (EDA)
EDTA, DISODIUM; EDTA, Disodium Salt Dihydrate; Ethylenediaminetetraacetic acid disodium salt dihydrate; Ethanediylbis(N-(carboxymethyl)glycine) disodium salt; Disodium dihydrogen ethylenediaminetetraacetate; Versene disodium salt;cas no: 139-33-3
ETHYLENEDIAMINETETRAACETIC ACID (EDTA)
Ethylenediaminetetraacetic Acid (EDTA) is a colorless crystalline solid.
Ethylenediaminetetraacetic Acid (EDTA) is slightly soluble in water.


CAS Number: 60-00-4 (free acid)
6381-92-6 (dihydrate disodium salt)
EC Number: 200-449-4
MDL number: MFCD00003541
Linear Formula: (HO2CCH2)2NCH2CH2N(CH2CO2H)2
Molecular Formula : C10H16N2O8



SYNONYMS:
(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid, Edathamil, (Ethylenedinitrilo)tetraacetic acid, Ethylenedinitrilotetraacetic acid, EDTA, EDTA, Edetic acid, Ethylenediaminetetraacetic acid, 60-00-4, Edathamil, Sequestrol, Versene, Havidote, Titriplex, EDTA acid, Versene acid, Endrate, Cheelox, Gluma cleanser, Sequestrene aa, Sequestric acid, Warkeelate acid, Komplexon ii, Tetrine acid, Quastal Special, Metaquest A, Trilon bw, Titriplex II, Hamp-ene acid, Cheelox BF acid, Trilon BS, Celon A, Celon ATH, Chelest 3A, Questex 4H, (Ethylenedinitrilo)tetraacetic acid, Chemcolox 340, Universne acid, EDTA (chelating agent), Dissolvine E, Vinkeil 100, Nullapon B acid, Nullapon bf acid, Nervanaid B acid, Perma kleer 50 acid, Clewat TAA, Ethylenedinitrilotetraacetic acid, Acide edetique, Acido edetico, Acidum edeticum, Caswell No. 438, Versenate, ICRF 185, Calcium disodium versenate, Ethylenebisiminodiacetic acid, Ethylenediamine-N,N,N',N'-tetraacetic acid, SEQ 100, YD 30, Disodium EDTA, CCRIS 946, Chelaton 3, Ethylenebis(iminodiacetic acid), HSDB 809, Acide ethylenediaminetetracetique, ETHYLENEDIAMINE TETRAACETIC ACID, Cheladrate, Edetate calcium, Edetate disodium, Acide edetique [INN-French], Acido edetico [INN-Spanish], Acidum edeticum [INN-Latin], Acetic acid, (ethylenedinitrilo)tetra-, EPA Pesticide Chemical Code 039101, Ethylenediaminetetraacetate, Kyselina ethylendiamintetraoctova, Tricon bw, Acid, Edetic, AI3-17181, H4edta, 3,6-Diazaoctanedioic acid, 3,6-bis(carboxymethyl)-, Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, 470462-56-7, EINECS 200-449-4, UNII-9G34HU7RV0, Edetate, BRN 1716295, Edta disodium, Versene-13C4, 9G34HU7RV0, Disodium edetate, Disodium versene, Endrate disodium, Sodium versenate, Edetic acid disodium salt, Kyselina ethylendiamintetraoctova [Czech], Acetic acid, 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetrakis-, Acide ethylenediaminetetracetique [French], Disodium edetate dihydrate, DTXSID6022977, Metaquest B, N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine), CHEBI:42191, ethylene diamine tetraacetic acid, Kiresuto B, Chelaplex III, Diso-Tate, Titriplex III, 2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid, Chelaton III, Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine), Versene NA, Triplex III, Disodium versenate, Edathamil disodium, Trilon BD, Versene Na2, Disodium sequestrene, Disodium tetracemate, EDTA disodium salt, MFCD00003541, EDTA, ion(4-), CHEMBL858, Sequestrene sodium 2, 2,2',2'',2'''-(ethane-1,2-diylbis(azanetriyl))tetraacetic acid, 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid, {[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID, Disodium salt of EDTA, ethylenediamine tetracetic acid, DTXCID902977, Perma Kleer Di Crystals, (ethylenedinitrilo)tetraacetic acid, ion(4-), Calcium disodium versenate (TN), ethylene-diamine tetraacetic acid, 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetic acid, EC 200-449-4, 4-04-00-02449 (Beilstein Handbook Reference), EDT, Ethylenediaminetetraacetic acid disodium salt, Edetate calcium disodium (USP), Sequestrene Na2, Trilon B, Selekton B2, Disodium ethylenediaminetetraacetate, (ethane-1,2-diyldinitrilo)tetraacetic acid, EDETIC ACID (II), EDETIC ACID [II], Perma kleer 50 crystals disodium salt, Disodium (ethylenedinitrilo)tetraacetate, Disodium ethylenediaminetetraacetic acid, EDETIC ACID (MART.), EDETIC ACID [MART.], CaEDTA, N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycine], CBC 50152966, DR-16133, Ethylenediaminetetraacetate, disodium salt, EDETIC ACID (USP-RS), EDETIC ACID [USP-RS], ANTICOAGULANT ETHYLENEDIAMINE TETRAACETIC ACID, Disodium diacid ethylenediaminetetraacetate, D'E.d.t.a. disodique, Disodium (ethylenedinitrilo)tetraacetic acid, 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate, Disodium dihydrogen ethylenediaminetetraacetate, Ethylenediaminetetraacetic acid, disodium salt, ANTICOAGULANT ETHYLENEDIAMINE TETRAACETIC ACID (EDTA), Disodium ethylenediamine-N,N,N',N'-tetraacetate, EDETIC ACID (EP MONOGRAPH), EDETIC ACID [EP MONOGRAPH], Disodium dihydrogen(ethylenedinitrilo)tetraacetate, 139-33-3, C10H16N2O8, NSC2760, NCGC00159485-02, 6381-92-6, disodium-edta, Edetic, Edetic acid [INN:BAN:NF], ((-(bis-carboxymethyl-amino)-ethyl)-carboxymethyl-amino)-acetic acid, (Ethylenedinitrilo)tetraacetic acid, disodium salt, Versenic Acid, Acid, Ethylenediaminetetraacetic, ([2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino)-acetic acid, {[2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetic acid, 2-(2-[bis(carboxymethyl)amino]ethylamino)acetic acid, Calcium Disodium Edetate (JAN), ethylenediamine tetra-acetic acid, Techrun DO, Acid, Ethylenedinitrilotetraacetic, EDTA, anhydrous, Zonon AO, EDTA, free acid, EDTA, free base, ACETIC ACID, (ETHYLENEDINITRILO)TETRA-, DISODIUM SALT, Versene acid (TN), ethylenediaminetetraacetic acid (edta), Caswell No 438, Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl))-, Ethylenediamine-tetraacetic acid (EDTA), Acroma DH 700, Spectrum_001018, Edetic acid (NF/INN), EDTA [VANDF], Spectrum2_000003, Spectrum3_000412, Spectrum4_000531, Spectrum5_000955, EDTA [INCI], Edetic acid [BAN:INN], EDETIC ACID [INN], EDTA [MI], EDETIC ACID [HSDB], EDTA, anhydrous ACS grade, ethylenediaminetetracetic acid, BSPBio_001964, Diaminoethanetetra-acetic acid, KBioGR_001161, KBioSS_001498, ethylenediaminetetraacetic-acid, MLS001249457, BIDD:ER0565, DivK1c_000777, EDETIC ACID [WHO-DD], SPBio_000005, ethylenediamine-tetraacetic acid, CHEBI:4735, KBio1_000777, KBio2_001498, KBio2_004066, KBio2_006634, KBio3_001184, (Ethylenedintrilo)tetraacetic acid, ethylen-ediamine tetra-acetic acid, ethylene diamine tetra acetic acid, NINDS_000777, (ethylenedinitrilo) tetraacetic acid, CS-B1827, HY-Y0682, STR08855, Tox21_202736, BDBM50330325, HB5135, s6350, AKOS001574475, Glycine, (N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, labeled with carbon-14, (ethane-1,2-diyldinitrilo)tetraacetate, DB00974, CAS-60-00-4, IDI1_000777, USEPA/OPP Pesticide Code: 039101, ETHYLENE BIS (IMINODIACETIC ACID), NCGC00159485-03, NCGC00159485-04, NCGC00260284-01, 688-55-1, AC-10615, SMR000058776, SBI-0051360.P003, E0084, Ethylenediaminetetraacetic acid, 2Na (EDTA), Ethylenediaminetetraacetic acid, LR, >=98%, NS00003929, EN300-71613, C00284, D00052, ethylene-N,N'-biscarboxymethyl-N,N'-diglycine, Ethylenediaminetetraacetic acid, p.a., 98.0%, AB00053468_03, Ethylenediaminetetraacetic acid, >=98.0% (KT), A832566, N,N'-1,2-Ethanediylbis(N-carboxymethyl)-glycine, N,N'-1,2-Ethanediylbis[N-(carboxymethyl)]glycine, N,N-1,2-Ethanediylbis[N-(carboxymethyl)]glycine, Q408032, SR-01000883946, Ethylenediaminetetraacetic Acid Sodium Salt Solution, Ethylenediaminetetraacetic acid, Cell Culture Reagent, J-610078, N, N-1,2-Ethanediylbis(N-(Carboxymethyl)Glycine), SR-01000883946-1, 3,6-Diazooctanedioic Acid, 3,6-bis(Carboxymethyl)-, 37C3C5E7-D921-445F-82D6-FEBF1AE5AEF5, Ethylenediaminetetraacetic acid, Electrophoresis Grade, Glycine, N, N'-1,2-Ethanediylbis-N-(Carboxymethyl), Z2588038976, Ethylenediaminetetraacetic acid, BioUltra, >=99.0% (KT), Ethylenediaminetetraacetic acid, 99.995% trace metals basis, Ethylenediaminetetraacetic acid, SAJ special grade, >=99.0%, Ethylenediaminetetraacetic acid, Vetec(TM) reagent grade, 98%, [{2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino]acetic acid, edta disodium salt, cal-ex decalcifier, buffer solution, ph 10.00, sodium di ethylenediamine tetraacetate dihydrate, ethylenediamine tetraacetic acid, disodium salt dihydrate, ethylenediamine tetraacetic acid, disodium salt, standard solution, sodium di ethylenediamine tetraacetate standard solution, ethylenedinitrilo tetraacetic acid disodium, dihydrate, reagent, Edetic Acid, N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine), Diaminoethanetetra-acetic acid, Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, Acetic acid, (ethylenedinitrilo)tetra-, Acide ethylenediaminetetracetique, Celon A, Celon ATH, Cheelox, Cheelox BF acid, Chemcolox 340, Complexon II, 3,6-Diazaoctanedioic acid, 3,6-bis(carboxymethyl)-, Edathamil, Edta, Edta acid, Endrate, Ethylenediamine-N,N,N',N'-tetraacetic acid, Ethylenedinitrilotetraacetic acid, Hamp-ene acid, Havidote, Komplexon ii, Kyselina ethylendiamintetraoctova, Metaquest A, Nervanaid B acid, Nullapon B acid, Nullapon BF acid, Perma kleer 50 acid, Questex 4H, SEQ 100, Sequestrene AA, Sequestric acid, Sequestrol, Tetrine acid, Titriplex, Tricon bw, Trilon BW, Versene, Versene acid, Vinkeil 100, Warkeelate acid, (Ethylenedintrilo)tetraacetic acid, EDTA, free base, EDTA, free acid, Trilon BS, ([2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino)-acetic acid, Titriplex II, YD 30, Quastal Special, Acetic acid, 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetrakis-, Gluma Cleanser, EDTA (chelating agent), Chelest 3A, ICRF 185, 2,2',2'',2'''-(Ethane-1,2-diyldinitrilo)te­traacetic acid, Dissolvine Z, 2-({2-[bis(carboxymet­hyl)amino]ethyl}(car­boxymethyl)ami­no)acetic acid, Diaminoethane-tetraacetic acid, Edetic acid, Ethylenedinitrilo-tetraacetic acid, Versene, EDTA, 2,2'',2'''',2''''''-(ethane-1,2-diylbis(azanetriyl))tetraacetic acid, Ethylenediaminetetraacetic acid, BioUltra, anhydrous, >=99% (titration), Glycine, N,N'-1, {2-ethanediylbis[N-(carboxymethyl)-,} disodium salt, {[2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetic acid(EDTA), 2-[2-[bis(2-hydroxy-2-oxoethyl)amino]ethyl-(2-hydroxy-2-oxoethyl)amino]ethanoic acid, Ethylenediaminetetraacetic acid, anhydrous, free-flowing, Redi-Dri(TM), >=98%, Ethylenediamine-N,N,N inverted exclamation mark ,N inverted exclamation mark -tetraacetic Acid-13C4 (|A-labels), Ethylenediaminetetraacetic acid, anhydrous, crystalline, BioReagent, suitable for cell culture, Ethylenediaminetetraacetic acid, anhydrous, free-flowing, powder, Redi-Dri(TM), ACS reagent, 99.4-100.6%, InChI=1/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20, N,N′-(Ethane-1,2-diyl)bis[N-(carboxymethyl)glycine], 2,2′,2′′,2′′′-(Ethane-1,2-diyldinitrilo)tetraacetic acid, EthyleneDiamineTetraAcetic acid, Diaminoethane-tetraacetic acid,



Ethylenediaminetetraacetic Acid (EDTA) is a colorless crystalline solid.
Ethylenediaminetetraacetic Acid (EDTA) is slightly soluble in water.
Ethylenediaminetetraacetic Acid (EDTA) is used in chemical analysis, to make detergents and cleaning compounds, and for many other uses.


Ethylenediaminetetraacetic Acid (EDTA) is a tetracarboxylic acid, an ethylenediamine derivative and a polyamino carboxylic acid.
Ethylenediaminetetraacetic Acid (EDTA) has a role as an antidote, a geroprotector, a chelator, a copper chelator and an anticoagulant.
Ethylenediaminetetraacetic Acid (EDTA) is a conjugate acid of an EDTA(2-).


Ethylenediaminetetraacetic Acid (EDTA) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 tonnes per annum.
Ethylenediaminetetraacetic Acid (EDTA) is the commonly used abbreviation for (Ethylene­dinitrilo)­tetra­acetic Acid (also called Ethylene­diamine­tetra­acetic Acid or Edetic Acid).


The Disodium salt of Ethylenediaminetetraacetic Acid (EDTA) is the most commonly used form of this versatile organic complexing agent, which is used for the determination of many metal ions either by direct titration or by back-titration.
Adjustment of reaction conditions, either by controlling the pH or by use of masking agents, and selection of the appropriate indicator permits a wide variety of metal ions to be determined using Ethylenediaminetetraacetic Acid (EDTA).


Ethylenediaminetetraacetic Acid (EDTA) has a claw-like molecular structure that binds to heavy metals and other toxins.
Ethylenediaminetetraacetic Acid (EDTA) after its own abbreviation, is an aminopolycarboxylic acid with the formula [CH2N(CH2CO2H)2]2.
This white, water-insoluble solid, Ethylenediaminetetraacetic Acid (EDTA), is widely used to bind to iron (Fe2+/Fe3+) and calcium ions (Ca2+), forming water-soluble complexes even at neutral pH.


Ethylenediaminetetraacetic Acid (EDTA) is a Lead Chelator and Anti-coagulant.
The mechanism of action of Ethylenediaminetetraacetic Acid (EDTA) is as a Lead Chelating Activity and Calcium Chelating Activity.
The physiologic effect of Ethylenediaminetetraacetic Acid (EDTA) is by means of Decreased Coagulation Factor Activity.


Ethylenediaminetetraacetic Acid (EDTA) is a natural product found in Perilla frutescens, Apis cerana, and other organisms with data available.
Ethylenediaminetetraacetic Acid (EDTA) is a white odourless, colourless crystalline powder, with a melting point of 240C at which it decomposes.
Ethylenediaminetetraacetic Acid (EDTA) is insoluble in cold water, alcohol and general organic solvents, slightly soluble in water, soluble in sodium hydroxide, sodium carbonate and ammonia solution, soluble in boiling water.


The alkali metal salts are soluble in water.
Ethylenediaminetetraacetic Acid (EDTA) is an important complexing agent.
Ethylenediaminetetraacetic Acid (EDTA) is an organic compound with the chemical formula C10H16N2O8 and is a white powder under normal temperature and pressure.


Ethylenediaminetetraacetic Acid (EDTA) is a chelating agent that can bind with Mg2+, Ca2+, Mn2+, Fe2+ and other divalent metal ions.
Mg2+ is often used as an inhibitor of nucleases and proteases because most nucleases and some proteases require Mg2+.
Ethylenediaminetetraacetic Acid (EDTA) is also known to inhibit a range of metallopeptidases, the method of inhibition occurs via the chelation of the metal ion required for catalytic activity.


Ethylenediaminetetraacetic Acid (EDTA) can also be used to test for bioavailability of heavy metals in sediments.
Ethylenediaminetetraacetic Acid (EDTA), Disodium Salt, Dihydrate (Na2EDTA•2H2O), is a chelator of divalent metal cations.
Ethylenediaminetetraacetic Acid (EDTA) is suitable for biochemistry or molecular biology applications.


Ethylenediaminetetraacetic Acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium).
Ethylenediaminetetraacetic Acid (EDTA) has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities.
Ethylenediaminetetraacetic Acid (EDTA) is a common chelating agent, which means it binds strongly to metal ions to form stable, water-soluble compounds.
This function lends itself to widespread applications.



USES and APPLICATIONS of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) is used in the following products: fertilisers and pH regulators and water treatment products.
Release to the environment of Ethylenediaminetetraacetic Acid (EDTA) can occur from industrial use: formulation of mixtures and formulation in materials.
Ethylenediaminetetraacetic Acid (EDTA) is used in the following products: pH regulators and water treatment products.


Ethylenediaminetetraacetic Acid (EDTA) is used in the following areas: mining, scientific research and development and health services.
Ethylenediaminetetraacetic Acid (EDTA) is used for the manufacture of: and chemicals.
Ethylenediaminetetraacetic Acid (EDTA) is also used as an anticoagulant for blood specimens and is applied as a treatment of lead poisoning.


Release to the environment of Ethylenediaminetetraacetic Acid (EDTA) can occur from industrial use: as processing aid, in processing aids at industrial sites, in the production of articles and of substances in closed systems with minimal release.
Ethylenediaminetetraacetic Acid (EDTA) is used in the following products: fertilisers.


Other release to the environment of Ethylenediaminetetraacetic Acid (EDTA) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Release to the environment of Ethylenediaminetetraacetic Acid (EDTA) can occur from industrial use: manufacturing of the substance and formulation of mixtures.
Ethylenediaminetetraacetic Acid (EDTA) is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Ethylenediaminetetraacetic Acid (EDTA) is used in the following products: washing & cleaning products, coating products, polishes and waxes, biocides (e.g. disinfectants, pest control products), adhesives and sealants, fillers, putties, plasters, modelling clay, non-metal-surface treatment products, photo-chemicals, air care products, metal surface treatment products and textile treatment products and dyes.


Other release to the environment of Ethylenediaminetetraacetic Acid (EDTA) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints) and outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).


Other release to the environment of Ethylenediaminetetraacetic Acid (EDTA) is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).


Ethylenediaminetetraacetic Acid (EDTA) can be found in complex articles, with no release intended: vehicles, machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and electrical batteries and accumulators.
Ethylenediaminetetraacetic Acid (EDTA) is intended to be released from: packaging material for metal parts (releasing grease/corrosion inhibitors).


Ethylenediaminetetraacetic Acid (EDTA) can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture), metal (e.g. cutlery, pots, toys, jewellery), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), rubber (e.g. tyres, shoes, toys), wood (e.g. floors, furniture, toys) and plastic (e.g. food packaging and storage, toys, mobile phones). Ethylenediaminetetraacetic Acid (EDTA) is intended to be released from scented: clothes, eraser, toys, paper products and CDs.


Ethylenediaminetetraacetic Acid (EDTA) is used in the following areas: agriculture, forestry and fishing and formulation of mixtures and/or re-packaging.
Release to the environment of Ethylenediaminetetraacetic Acid (EDTA) can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid, and of substances in closed systems with minimal release.


Other release to the environment of Ethylenediaminetetraacetic Acid (EDTA) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Ethylenediaminetetraacetic Acid (EDTA) is a chelating agent (chelating agents) that sequesters a variety of polyvalent cations.
Ethylenediaminetetraacetic Acid (EDTA) is used in pharmaceutical manufacturing and as a food additive.
Ethylenediaminetetraacetic Acid (EDTA) is the acid form of edetate, a chelating agent with anti-hypercalcemic and anticoagulant properties.


Ethylenediaminetetraacetic Acid (EDTA) binds calcium and heavy metal ions, forming soluble stable complexes which are readily excreted by the kidneys.
This results in a decrease in serum calcium levels.
Ethylenediaminetetraacetic Acid (EDTA) is also used as an anticoagulant for blood specimens and is applied as a treatment of lead poisoning.


Chelation therapy is a treatment that involves repeated intravenous (IV) administration of a chemical solution of Ethylenediaminetetraacetic Acid (EDTA).
Ethylenediaminetetraacetic Acid (EDTA) is used to treat acute and chronic lead poisoning by pulling toxins (including heavy metals such as lead, cadmium, and mercury) from the bloodstream.


The word "chelate" comes from the Greek root chele, which means "to claw."
The U.S. Food and Drug Administration (FDA) approved Ethylenediaminetetraacetic Acid (EDTA) chelation therapy as a treatment for lead and heavy metal poisoning.


Ethylenediaminetetraacetic Acid (EDTA) is also used as an emergency treatment for hypercalcemia (excessive calcium levels) and the control of ventricular arrhythmias (abnormal heart rhythms) associated with digitalis toxicity.
Ethylenediaminetetraacetic Acid (EDTA) is a medication used in the management and treatment of heavy metal toxicity.


Ethylenediaminetetraacetic Acid (EDTA) is in the chelating class of drugs.
Ethylenediaminetetraacetic Acid (EDTA) is used textiles and paper.
In industry, Ethylenediaminetetraacetic Acid (EDTA) is mainly used to sequester (bind or confine) metal ions in aqueous solution.


In the textile industry, Ethylenediaminetetraacetic Acid (EDTA) prevents metal ion impurities from modifying colours of dyed products.
In the pulp and paper industry, Ethylenediaminetetraacetic Acid (EDTA) inhibits the ability of metal ions, especially Mn2+, from catalysing the disproportionation of hydrogen peroxide, which is used in chlorine-free bleaching.


Food: In a similar manner, Ethylenediaminetetraacetic Acid (EDTA) is added to some food as a preservative or stabiliser to prevent catalytic oxidative decolouration, which is catalysed by metal ions.
Ethylenediaminetetraacetic Acid (EDTA) is used lead poisoning and heavy metal toxicity.


Chelation therapy using Ethylenediaminetetraacetic Acid (EDTA) is the medically-accepted treatment for lead poisoning.
Injected intravenously and once in the bloodstream, Ethylenediaminetetraacetic Acid (EDTA) traps lead and other metals, forming a compound that the body can eliminate in the urine.


The process generally takes 1 to 3 hours.
Other heavy metal poisonings treated with chelation include mercury, arsenic, aluminum, chromium, cobalt, manganese, nickel, selenium, zinc, tin, and thallium.


Chelating agents other than Ethylenediaminetetraacetic Acid (EDTA) are also used to clear several of these substances from the bloodstream.
Ethylenediaminetetraacetic Acid (EDTA) is thus used to dissolve Fe- and Ca-containing scale as well as to deliver iron ions under conditions where its oxides are insoluble.


Ethylenediaminetetraacetic Acid (EDTA) is available as several salts, notably disodium EDTA, sodium calcium edetate, and tetrasodium EDTA, but these all function similarly.
Eyedrops: Ethylenediaminetetraacetic Acid (EDTA) serves as a preservative (usually to enhance the action of another preservative such as benzalkonium chloride or thiomersal) in ocular preparations and eyedrops.


Cosmetics: In shampoos, cleaners, and other personal care products, Ethylenediaminetetraacetic Acid (EDTA) salts are used as a sequestering agent to improve their stability in air.
Ethylenediaminetetraacetic Acid (EDTA) is widely used, can be used for processing colour photographic materials bleach fixing bath washing, dyeing auxiliaries, textile processing auxiliaries, detergent, stabiliser, synthetic rubber and polymerization initiator.


Ethylenediaminetetraacetic Acid (EDTA) is used Agricultural Formulations, Bleaching (Pulp), Cleaning (Hard Surface), Cleaning (Industrial), Cleaning (Institutional), Cleaning (Metal), Cleaning (Offshore), Drilling/Completion Fluids,
Industrial Cleaning, Offshore Cleaning, Oilfield, Photography, and Textile.


Ethylenediaminetetraacetic Acid (EDTA) is predominantly used in agriculture, water treatment, pulp and paper industries and also used in the manufacture of cleaners and detergents
Ethylenediaminetetraacetic Acid (EDTA) is used chelating agents bind or capture trace amounts of iron, copper, manganese, calcium and other metals that occur naturally in many materials.


Such naturally occurring metals can cause chemical degradation, discoloration, scaling, instability, rancidity, ineffective cleaning performance and other problems.
In Metalworking industries Ethylenediaminetetraacetic Acid (EDTA) is used for surface preparation, metal cleaning, metal plating, and in metalworking fluids.


In Cleaning products, Ethylenediaminetetraacetic Acid (EDTA) is employed to remove hard water scale, soap film, and inorganic scales.
Ethylenediaminetetraacetic Acid (EDTA) is commonly used in a wide variety of cleaning products and formulations, including hard surface cleaners, laundry detergents, bactericidal cleaners, vehicle washes etc.


Ethylenediaminetetraacetic Acid (EDTA) finds many specialised uses in the biomedical labs, such as in veterinary ophthalmology as an anticollagenase to prevent the worsening of corneal ulcers in animals.
In tissue culture Ethylenediaminetetraacetic Acid (EDTA) is used as a chelating agent that binds to calcium and prevents joining of cadherins between cells, preventing clumping of cells grown in liquid suspension, or detaching adherent cells for passaging.


In histopathology, Ethylenediaminetetraacetic Acid (EDTA) can be used as a decalcifying agent making it possible to cut sections using a microtome once the tissue sample is demineralised.
Ethylenediaminetetraacetic Acid (EDTA) is also used to remove crud (corroded metals) from fuel rods in nuclear reactors.


Ethylenediaminetetraacetic acid (EDTA) is a substituted diamine widely used in domestic and industrial applications.
Ethylenediaminetetraacetic Acid (EDTA) chelate metal divalent cations, such as calcium, magnesium, zinc, copper, and manganese, to form metal-EDTA complexes.


Ethylenediaminetetraacetic Acid (EDTA) is suitable for cleaning products and detergent formulations.
In the paper and pulp industry, Ethylenediaminetetraacetic Acid (EDTA) reduces the adverse effects of metal ions on bleaching.
As an antibacterial agent, Ethylenediaminetetraacetic Acid (EDTA) can remove calcium and magnesium divalent cations in the outer membrane and cause the loss of membrane lipopolysaccharide, making bacteria sensitive to bactericides.


Free Ethylenediaminetetraacetic Acid (EDTA) has an adverse effect on mammalian reproduction and development.
Ethylenediaminetetraacetic Acid (EDTA) can sequester ions in sediments that cause atherosclerosis, cancer and heart disease.
Ethylenediaminetetraacetic Acid (EDTA) reduces free radical reactions and oxidation processes, which helps to overcome cell membrane damage.


Ethylenediaminetetraacetic Acid (EDTA) can bind to calcium and reduce the risk of developing hypercalcemia in cancer patients.
The transmembrane Ethylenediaminetetraacetic Acid (EDTA) gradient method facilitates drug delivery, thereby enhancing drug retention and therapeutic effects and reducing levels of cytotoxicity.


Ethylenediaminetetraacetic Acid (EDTA) has a wide range of uses.
Ethylenediaminetetraacetic Acid (EDTA) can be used as bleaching fixative solution for color sensitive material washing processing, dyeing aid, fiber treatment aid, cosmetic additive, blood anticoagulant, detergent, stabilizer and synthetic rubber polymerization initiator.


Ethylenediaminetetraacetic Acid (EDTA) can form stable water-soluble complexes with alkaline earth metals, rare earth elements and transition metals.
In addition to sodium, there are ammonium salts and various salts of iron, magnesium, calcium, copper, manganese, zinc, cobalt and aluminum, all of which have different uses.


In addition, Ethylenediaminetetraacetic Acid (EDTA) can also be used to enable the rapid excretion of harmful radioactive metals from the body to play a detoxification role.
Ethylenediaminetetraacetic Acid (EDTA)'s also a water treatment agent.


Ethylenediaminetetraacetic Acid (EDTA) is also an important indicator, but it is used for titrating metals such as nickel and copper.
When used, Ethylenediaminetetraacetic Acid (EDTA) should be used together with ammonia to play the role of indicator.
Ethylenediaminetetraacetic Acid (EDTA) is used for in vitro anticoagulation of blood.


Ethylenediaminetetraacetic Acid (EDTA) is an anticoagulant additive for clinical blood testing.
Ethylenediaminetetraacetic Acid (EDTA) is used for pretreatment (anticoagulation) of blood samples during clinical blood collection and testing.
Ethylenediaminetetraacetic Acid (EDTA) is high solubility and fast anticoagulation.


Ethylenediaminetetraacetic Acid (EDTA) is mainly used to bind metal ions in aqueous solution making EDTA useful in a wide variety of uses as a chelating agent.
Ethylenediaminetetraacetic Acid (EDTA) is widely used to dissolve limescale.


In shampoos, cleaners, and other personal care products Ethylenediaminetetraacetic Acid (EDTA) salts are used as stabilizers.
Ethylenediaminetetraacetic Acid (EDTA) is added to some food as a preservative or stabilizer to prevent catalytic oxidative decoloration, which is catalyzed by metal ions.


In the pulp and paper industry, Ethylenediaminetetraacetic Acid (EDTA) inhibits the ability of metal ions, especially Mn2+, from catalyzing the disproportionation of hydrogen peroxide, which is used in "chlorine-free bleaching."
Ethylenediaminetetraacetic Acid (EDTA) decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification.


Ethylenediaminetetraacetic Acid (EDTA) can alleviate the liver fibrosis.
Ethylenediaminetetraacetic Acid (EDTA) can be used for coronary artery disease and neural system disease research.
Ethylenediaminetetraacetic Acid (EDTA) can also be used to remove the inhibition of heavy metal ions on enzymes.


Chelating agent, Ethylenediaminetetraacetic Acid (EDTA) is used in many enzyme buffers and at higher concentrations, as enzyme inactivator
Detergent uses of Ethylenediaminetetraacetic Acid (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) can be used as a labeling buffer component for washing during cell lysis {155}.


Supplements: Ethylenediaminetetraacetic Acid (EDTA) is used as a supplement for synthetic tubal fluid culture 1 (SOFC1) medium for embryo culture.
Ethylenediaminetetraacetic Acid (EDTA) is used as a complexing agent for many cations.
Ethylenediaminetetraacetic Acid (EDTA) prevents metal ion impurities and used to remove excess iron from the body.


Ethylenediaminetetraacetic Acid (EDTA) acts as a sequestering agent in cosmetic products.
Ethylenediaminetetraacetic Acid (EDTA) is used as a complexing agent for many cations.
Ethylenediaminetetraacetic Acid (EDTA) prevents metal ion impurities and used to remove excess iron from the body.


Ethylenediaminetetraacetic Acid (EDTA) acts as a sequestering agent in cosmetic products.
For example, Ethylenediaminetetraacetic Acid (EDTA) may be added as a stabilizer to foods or cosmetic products in order to sequester metal ions that would otherwise act as catalysts towards the production of harmful or undesirable products (e.g. discoloration, carcinogens).


In other cases, Ethylenediaminetetraacetic Acid (EDTA) can improve the solubility of otherwise insoluble metals; for example, in agricultural applications, EDTA can improve iron bioavailability to plants.
Ethylenediaminetetraacetic Acid (EDTA) has also been used for chelation therapy, to treat heavy metal poisoning.


Ethylenediaminetetraacetic Acid (EDTA) products are used for hair, skin, chelation, endodontics, in food, in skincare, shampoo and dentistry.
Ethylenediaminetetraacetic Acid (EDTA) is a representative chelating agent.
Ethylenediaminetetraacetic Acid (EDTA) is an important complexing agent.


-Cell sorting analysis uses of Ethylenediaminetetraacetic Acid (EDTA):
Firstly, Ethylenediaminetetraacetic Acid (EDTA) is used single-cell suspension of spleen dendritic cells for magnetic bead cell sorting.
Secondly, incubate EpCAM + cells and FITC-labeled antibodies for cell sorting analysis.


-The applications of Ethylenediaminetetraacetic acid (EDTA) have been reported as following:
Complexing agent uses of Ethylenediaminetetraacetic Acid (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) is a hydrophilic gold chelator that converts metal ions into inactive, cyclized metal complexes.
Therefore, Ethylenediaminetetraacetic Acid (EDTA) can be used in industry to solve metal pollutants.


-Blood anticoagulant uses of Ethylenediaminetetraacetic Acid (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) cannot be absorbed by the gastrointestinal tract.
Intravenous injection of sodium EDTA causes hypocalcemic hand-foot twitching.

Ethylenediaminetetraacetic Acid (EDTA) is commonly used for plasma or molecular diagnostics, and calcium chelation.
Ethylenediaminetetraacetic Acid (EDTA) can be used as an anticoagulant in blood cell count and cell morphology analysis.


-Other key applications for Ethylenediaminetetraacetic Acid (EDTA) include:
*In Photography as a bleach in photographic film processing.
*In the manufacturing of paper to maximize bleaching efficiency during pulping, prevent brightness reversion, and protect bleach potency.
*In Scale removal and prevention - to clean calcium and other types of scale from boilers, evaporators, heat exchangers, filter cloths, and glass-lined kettles.
*Water treatment - to control water hardness and scale-forming calcium and magnesium ions and to prevent scale formation.


-Laboratory applications of Ethylenediaminetetraacetic Acid (EDTA):
In the laboratory, Ethylenediaminetetraacetic Acid (EDTA) is widely used for scavenging metal ions: In biochemistry and molecular biology, ion depletion is commonly used to deactivate metal-dependent enzymes, either as an assay for their reactivity or to suppress damage to DNA, proteins, and polysaccharides.

Ethylenediaminetetraacetic Acid (EDTA) also acts as a selective inhibitor against dNTP hydrolyzing enzymes (Taq polymerase, dUTPase, MutT), liver arginase and horseradish peroxidase independently of metal ion chelation.

These findings urge the rethinking of the utilisation of Ethylenediaminetetraacetic Acid (EDTA) as a biochemically inactive metal ion scavenger in enzymatic experiments.

In analytical chemistry, Ethylenediaminetetraacetic Acid (EDTA) is used in complexometric titrations and analysis of water hardness or as a masking agent to sequester metal ions that would interfere with the analyses.


-Water softener uses of Ethylenediaminetetraacetic Acid (EDTA):
The reduction of water hardness in laundry applications and the dissolution of scale in boilers both rely on Ethylenediaminetetraacetic Acid (EDTA) and related complexants to bind Ca2+, Mg2+, as well as other metal ions.

Once bound to Ethylenediaminetetraacetic Acid (EDTA), these metal complexes are less likely to form precipitates or to interfere with the action of the soaps and detergents.
For similar reasons, cleaning solutions often contain Ethylenediaminetetraacetic Acid (EDTA).

In a similar manner Ethylenediaminetetraacetic Acid (EDTA) is used in the cement industry for the determination of free lime and free magnesia in cement and clinkers.
The solubilisation of Fe3+ ions at or below near neutral pH can be accomplished using Ethylenediaminetetraacetic Acid (EDTA).

This property is useful in agriculture including hydroponics. However, given the pH dependence of ligand formation, Ethylenediaminetetraacetic Acid (EDTA) is not helpful for improving iron solubility in above neutral soils.
Otherwise, at near-neutral pH and above, iron(III) forms insoluble salts, which are less bioavailable to susceptible plant species.


-Scrubbing uses of Ethylenediaminetetraacetic Acid (EDTA):
Aqueous [Fe(EDTA)]− is used for removing ("scrubbing") hydrogen sulfide from gas streams.
This conversion is achieved by oxidising the hydrogen sulfide to elemental sulfur, which is non-volatile:
2 [Fe(EDTA)]− + H2S → 2 [Fe(EDTA)]2− + S + 2 H+

In this application, the iron(III) centre is reduced to its iron(II) derivative, which can then be reoxidised by air.
In similar manner, nitrogen oxides are removed from gas streams using [Fe(EDTA)]2−.
The oxidising properties of [Fe(EDTA)]− are also exploited in photography, where it is used to solubilise silver particles.


-Analysis uses of Ethylenediaminetetraacetic Acid (EDTA):
In medical diagnosis and organ function tests (here, kidney function test), the chromium(III) complex [Cr(EDTA)]− (as radioactive chromium-51 (51Cr)) is administered intravenously and its filtration into the urine is monitored.

This method is useful for evaluating glomerular filtration rate (GFR) in nuclear medicine.
Ethylenediaminetetraacetic Acid (EDTA) is used extensively in the analysis of blood.
Ethylenediaminetetraacetic Acid (EDTA) is an anticoagulant for blood samples for CBC/FBCs, where the EDTA chelates the calcium present in the blood specimen, arresting the coagulation process and preserving blood cell morphology.

Tubes containing Ethylenediaminetetraacetic Acid (EDTA) are marked with lavender (purple) or pink tops.
Ethylenediaminetetraacetic Acid (EDTA) is also in tan top tubes for lead testing and can be used in royal blue top tubes for trace metal testing.
Ethylenediaminetetraacetic Acid (EDTA) is a slime dispersant, and has been found to be highly effective in reducing bacterial growth during implantation of intraocular lenses (IOLs).


-Alternative medicine uses of Ethylenediaminetetraacetic Acid (EDTA):
Some alternative practitioners believe Ethylenediaminetetraacetic Acid (EDTA) acts as an antioxidant, preventing free radicals from injuring blood vessel walls, therefore reducing atherosclerosis.
These ideas are unsupported by scientific studies, and seem to contradict some currently accepted principles.
The U.S. FDA has not approved it for the treatment of atherosclerosis.


-Ion-exchange chromatography uses of Ethylenediaminetetraacetic Acid (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) was used in separation of the lanthanide metals by ion-exchange chromatography.
Perfected by F. H. Spedding et al. in 1954, the method relies on the steady increase in stability constant of the lanthanide Ethylenediaminetetraacetic Acid (EDTA) complexes with atomic number.

Using sulfonated polystyrene beads and Cu2+ as a retaining ion, Ethylenediaminetetraacetic Acid (EDTA) causes the lanthanides to migrate down the column of resin while separating into bands of pure lanthanides.
The lanthanides elute in order of decreasing atomic number.

Due to the expense of this method, relative to countercurrent solvent extraction, ion exchange is now used only to obtain the highest purities of lanthanides (typically greater than 99.99%).


-Medicine uses of Ethylenediaminetetraacetic Acid (EDTA):
Sodium calcium edetate, an Ethylenediaminetetraacetic Acid (EDTA) derivative, is used to bind metal ions in the practice of chelation therapy, such as for treating mercury and lead poisoning.

Ethylenediaminetetraacetic Acid (EDTA) is used in a similar manner to remove excess iron from the body.
This therapy is used to treat the complication of repeated blood transfusions, as would be applied to treat thalassaemia.


-Dentistry uses of Ethylenediaminetetraacetic Acid (EDTA):
Dentists and endodontists use Ethylenediaminetetraacetic Acid (EDTA) solutions to remove inorganic debris (smear layer) and lubricate the root canals in endodontics.

This procedure helps prepare root canals for obturation.
Furthermore, Ethylenediaminetetraacetic Acid (EDTA) solutions with the addition of a surfactant loosen up calcifications inside a root canal and allow instrumentation (canal shaping) and facilitate apical advancement of a file in a tight or calcified root canal towards the apex.



PHYSICAL PROPERTIES OF ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
The chemical names of ethylenediaminetetraacetic acid include Ethylenediamine tetraacetic acid, (Ethylenedinitrilo) tetraacetic acid, Edetic acid and EDTA.
EDTA is white powder, which is soluble in sodium hydroxide, sodium carbonate and ammonia solution, and 160 parts of boiling water, and slightly soluble in cold water, insoluble in ethanol and general organic solvents.
It can form extremely stable water-soluble complexes with alkali metals, rare earth elements and transition metals.
EDTA decompose above its melting point 240°C.



SOLUBILITY OF ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) is soluble in sodium hydroxide, sodium carbonate, ammonia solution, acid and common organic solvents.
Ethylenediaminetetraacetic Acid (EDTA) is slightly soluble in water.



PHYSICAL AND CHEMICAL PROPERTIES OF ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) is used white odorless, tasteless, colorless crystalline powder, melting point 250℃ (decomposition).
Ethylenediaminetetraacetic Acid (EDTA) is insoluble in ethanol and general organic solvents, slightly soluble in cold water, soluble in aqueous solutions of sodium hydroxide, sodium carbonate and ammonia.

Ethylenediaminetetraacetic Acid (EDTA) can dissolve in more than 5% of inorganic acid, can also dissolve in ammonia and 160 parts of boiling water.
Ethylenediaminetetraacetic Acid (EDTA)'s alkali metal salts are soluble in water.



MOLARITY OF ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
Molarity is best used in expressing Ethylenediaminetetraacetic Acid (EDTA) concentration, because the reaction involves the complexation of one metal ion by one EDTA molecule or ion, whether the free acid form of EDTA or one of its more soluble Sodium salts is used.
The general reaction involving the Disodium salt is:

EDTA2- + Mn+ → [EDTA-M]+n-2
where M = Ca, Mg, Cd, Mn, Ni, Al, Zn, Bi, Co, Cu, or other metal ion

An indicator is added that forms a colored complex with some of the metal ion being determined.
When the endpoint is reached, all of the free metal ion has been complexed by the Ethylenediaminetetraacetic Acid (EDTA).
The last addition of Ethylenediaminetetraacetic Acid (EDTA) then removes the metal ion from its complex with the indicator, producing a color change.

The relative strength of the Ethylenediaminetetraacetic Acid (EDTA)-metal ion complex compared to that of the indicator-metal ion complex determines whether a direct titration or a back-titration is applicable.

Ethylenediaminetetraacetic Acid (EDTA) is most commonly used to determine hardness (i.e., Calcium and Magnesium ions) in water, where the pH must be approximately 10 and is usually controlled by adding a buffer such as Water Hardness Buffer.

Water Hardness Indicator (Eriochrome Black T), Eriochrome Blue Black R, Calmagite, and Murexide are used for hardness or Calcium determinations using Ethylenediaminetetraacetic Acid (EDTA).



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
CAS Number: 60-00-4
Molecular Weight: 292.24
Beilstein: 1716295
EC Number: 200-449-4
MDL Number: MFCD00003541
Physical State: Powder
Color: White
Odor: Odorless
Melting Point/Freezing Point: Melting point/range: 250 °C - dec.
Initial Boiling Point and Boiling Range: No data available
Flammability (solid, gas): No data available
Upper/Lower Flammability or Explosive Limits: No data available
Flash Point: Not applicable
Autoignition Temperature: No data available
Decomposition Temperature: > 220 °C

pH: 2.5 at 10 g/l at 23 °C
Viscosity:
Kinematic Viscosity: No data available
Dynamic Viscosity: No data available
Water Solubility: 0.4 g/l at 20 °C
Partition Coefficient (n-octanol/water): No data available
Vapor Pressure: No data available
Density: 1.46 g/cm³ at 20 °C
Relative Density: No data available
Relative Vapor Density: No data available
Particle Characteristics: No data available
Explosive Properties: No data available
Oxidizing Properties: None
Other Safety Information:
Dissociation constant: 8.85 - 10.44 at 20 °C
Molecular Weight: 292.24 g/mol

XLogP3-AA: -5.9
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 10
Rotatable Bond Count: 11
Exact Mass: 292.09066547 g/mol
Monoisotopic Mass: 292.09066547 g/mol
Topological Polar Surface Area: 156 Ų
Heavy Atom Count: 20
Formal Charge: 0
Complexity: 316
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1

Compound Is Canonicalized: Yes
CAS No. 60-00-4
EC No. 200-449-4
Formula: (HO2CCH2)2NCH­2CH2N(CH2CO2H)2
Molecular weight: 292.24
Appearance: white crystalline solid.
Relative density: 0.86 g/cm3
Melting Point: 220C (428F)
Solubility: Very slightly soluble in cold water.
pH (1%): 2.5
Chemical Formula: C10H16N2O8
Molar Mass: 292.244 g·mol⁻¹
Appearance: Colorless crystals
Density: 0.860 g cm⁻³ (at 20 °C)
Log P: -0.836
Acidity (pKa): 2.0, 2.7, 6.16, 10.26

Thermochemistry:
Standard Enthalpy of Formation (ΔfH⦵298): -1765.4 to -1758.0 kJ mol⁻¹
Standard Enthalpy of Combustion (ΔcH⦵298): -4461.7 to -4454.5 kJ mol⁻¹
CAS Number: 65501-24-8
Packing: 500g/bottle
Appearance: White crystal powder
Chemical Properties: Odorless, soluble in water, easy to absorb moisture
Molecular Weight: 442.56
pH Value: 7.3±1 (5% aqueous solution, g/ml)
Solubility in Water: ≥60% (g/ml, 25℃)
Validity Period: 3 years
Storage Conditions: Dry and sealed at room temperature.



FIRST AID MEASURES of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P2
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available


ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT

Ethylenediaminetetraacetic acid disodium salt, often abbreviated as Ethylenediaminetetraacetic acid disodium salt, is a chemical compound with the molecular formula C10H14N2Na2O8.
Ethylenediaminetetraacetic acid disodium salt is a synthetic organic compound derived from ethylenediamine and acetic acid.
Ethylenediaminetetraacetic acid disodium salt is a chelating agent, which means it can form stable complexes with metal ions by coordinating with their positively charged ions.

CAS Number: 6381-92-6
EC Number: 205-358-3



APPLICATIONS


Ethylenediaminetetraacetic acid disodium salt (Ethylenediaminetetraacetic acid disodium salt) is widely used in the field of analytical chemistry.
In analytical chemistry, Ethylenediaminetetraacetic acid disodium salt serves as a chelating agent to determine metal ion concentrations through complexometric titrations.
Ethylenediaminetetraacetic acid disodium salt is used to sequester and remove metal ions from water in various industrial and laboratory applications.

In the food and beverage industry, Ethylenediaminetetraacetic acid disodium salt is utilized as a food additive (E385) to preserve the color and flavor of processed foods.
Ethylenediaminetetraacetic acid disodium salt prevents the oxidation of food components by binding to metal ions that catalyze oxidation reactions.
Ethylenediaminetetraacetic acid disodium salt is employed in pharmaceuticals as a stabilizing agent and preservative in some medications.

In the cosmetics and personal care industry, it serves as a stabilizer in various products, including creams and lotions.
Medical applications include the use of Ethylenediaminetetraacetic acid disodium salt in chelation therapy to treat heavy metal poisoning.
Ethylenediaminetetraacetic acid disodium salt can effectively bind to heavy metal ions, such as lead and mercury, aiding in their removal from the body.
Ethylenediaminetetraacetic acid disodium salt is used as an anticoagulant in blood collection tubes to prevent clotting and maintain sample integrity.

Ethylenediaminetetraacetic acid disodium salt is a common component in many laboratory reagents and buffers used in molecular biology and biochemistry research.
In the textiles industry, Ethylenediaminetetraacetic acid disodium salt is utilized as a color-removing agent in the dyeing and printing processes.
Ethylenediaminetetraacetic acid disodium salt is employed as a metal ion control agent in pulp and paper manufacturing to improve paper quality.

In the photography industry, Ethylenediaminetetraacetic acid disodium salt is used in photographic development solutions to prevent the formation of unwanted precipitates.
Ethylenediaminetetraacetic acid disodium salt plays a role in soil science, where it is used to chelate metal ions in soil samples for analysis.
In the oil and gas industry, it helps prevent scale formation by sequestering metal ions that can cause scaling in pipelines and equipment.

Ethylenediaminetetraacetic acid disodium salt is a key ingredient in some household cleaning products, contributing to their efficacy in removing mineral deposits.
In the electronics industry, it is used as a cleaning agent to remove metal ion contaminants from semiconductor surfaces.

Ethylenediaminetetraacetic acid disodium salt is added to some shampoos and personal care products to improve product stability and shelf life.
Ethylenediaminetetraacetic acid disodium salt is used in the manufacture of detergents to enhance their performance by binding to metal ions that interfere with cleaning.
Ethylenediaminetetraacetic acid disodium salt is employed in water treatment plants to reduce the effects of hard water and prevent scale buildup in pipes.

Ethylenediaminetetraacetic acid disodium salt is used in the preservation of archaeological and historical artifacts to prevent metal corrosion.
In the agricultural industry, it can be used to correct nutrient deficiencies in plants by chelating essential metals.
Ethylenediaminetetraacetic acid disodium salt is employed in the development of nanomaterials and nanoparticles for various applications.

Ethylenediaminetetraacetic acid disodium salt is commonly used in the pharmaceutical industry to improve the stability of certain medications.
In the textile industry, Ethylenediaminetetraacetic acid disodium salt serves as a color-removing agent and as a component in dyeing processes.
Ethylenediaminetetraacetic acid disodium salt finds application in the manufacture of soaps and detergents to enhance their cleaning efficiency.

In the cosmetics and personal care sector, it is utilized to maintain product stability and prevent rancidity.
Ethylenediaminetetraacetic acid disodium salt is employed in the preservation of art and historical artifacts to prevent metal corrosion.
In the oil drilling industry, it is added to drilling fluids to control the adverse effects of metal ions.

Ethylenediaminetetraacetic acid disodium salt plays a role in water treatment by sequestering metal ions that can cause scale buildup.
In the field of molecular biology, Ethylenediaminetetraacetic acid disodium salt is used as an essential component in DNA and RNA extraction.

Ethylenediaminetetraacetic acid disodium salt contributes to the formulation of hemodialysis solutions to remove excess metals from the blood.
Ethylenediaminetetraacetic acid disodium salt is added to anticoagulant solutions used in blood collection tubes to maintain sample quality.

Ethylenediaminetetraacetic acid disodium salt helps improve the stability of certain photographic chemicals and prevents precipitation.
In the automotive industry, it is used as an ingredient in automotive cooling systems to inhibit corrosion.

Ethylenediaminetetraacetic acid disodium salt can be found in some eye drops and ointments, contributing to their preservation.
Ethylenediaminetetraacetic acid disodium salt is employed in the electronics industry for cleaning and descaling semiconductor surfaces.
Ethylenediaminetetraacetic acid disodium salt is utilized in the production of specialty chemicals, including catalysts and reagents.

In the mining and mineral processing industry, it is added to flotation reagents for ore separation.
Ethylenediaminetetraacetic acid disodium salt is used in the manufacture of cleaning agents for removing mineral deposits.

In the agriculture sector, it may be employed as a micronutrient fertilizer.
Ethylenediaminetetraacetic acid disodium salt plays a role in the formulation of certain veterinary medications.
In the construction industry, it is used to improve the workability of cement and concrete mixtures.

Ethylenediaminetetraacetic acid disodium salt is used in the preservation of samples in laboratories and research settings.
Ethylenediaminetetraacetic acid disodium salt contributes to the stability of certain chemical solutions used in analytical chemistry.
In the food and beverage industry, it is employed as a sequestrant to enhance the quality of processed foods.

Ethylenediaminetetraacetic acid disodium salt is sometimes added to swimming pool water to control metal ion content and prevent staining.
Ethylenediaminetetraacetic acid disodium salt serves as a valuable tool in environmental chemistry for the analysis of metal ion concentrations in natural water sources.

In the pharmaceutical industry, Ethylenediaminetetraacetic acid disodium salt is used to enhance the stability of certain medications and prevent degradation caused by metal ions.
Ethylenediaminetetraacetic acid disodium salt plays a crucial role in analytical chemistry, particularly in complexometric titrations to determine metal ion concentrations in samples.
Ethylenediaminetetraacetic acid disodium salt is employed in the food and beverage industry as a food additive (E385) to maintain product color and flavor.
Ethylenediaminetetraacetic acid disodium salt is added to canned and packaged foods to prevent the deterioration of food quality due to metal-induced oxidation reactions.

Ethylenediaminetetraacetic acid disodium salt is utilized in the cosmetics and personal care industry to stabilize and extend the shelf life of various products.
In medical applications, Ethylenediaminetetraacetic acid disodium salt is used as an anticoagulant in blood collection tubes to ensure the integrity of blood samples.
Ethylenediaminetetraacetic acid disodium salt is a vital component in chelation therapy, a medical treatment for heavy metal poisoning, where it binds to and facilitates the removal of toxic metal ions from the body.
Ethylenediaminetetraacetic acid disodium salt is applied in the preservation of historical artifacts and artworks to prevent corrosion and degradation.
In the oil and gas industry, Ethylenediaminetetraacetic acid disodium salt is used to prevent scale formation by sequestering metal ions that can cause scaling in pipelines and equipment.

Ethylenediaminetetraacetic acid disodium salt contributes to the removal of metal contaminants from semiconductor surfaces in the electronics industry.
Ethylenediaminetetraacetic acid disodium salt is used in soil science to chelate metal ions in soil samples for analysis.

In the pulp and paper industry, it acts as a metal ion control agent to enhance paper quality and prevent coloration.
Ethylenediaminetetraacetic acid disodium salt plays a role in the development of nanomaterials and nanoparticles for various applications.
Ethylenediaminetetraacetic acid disodium salt is used as a cleaning agent in the electronics industry to remove metal ion contaminants from circuit boards.

Ethylenediaminetetraacetic acid disodium salt is employed in the mining industry as a flotation reagent to assist in ore separation.
In the automotive sector, it is added to automotive cooling systems to prevent corrosion and scale formation.
Ethylenediaminetetraacetic acid disodium salt is an essential component in laboratory reagents and buffers used in molecular biology and biochemistry research.
Ethylenediaminetetraacetic acid disodium salt finds application in water treatment plants to reduce the effects of hard water and prevent scale buildup in pipes.

Ethylenediaminetetraacetic acid disodium salt is used as a component in some household cleaning products to improve their effectiveness in removing mineral deposits.
In photography, it helps maintain the stability of photographic development solutions by preventing precipitation.
Ethylenediaminetetraacetic acid disodium salt is added to some shampoos and personal care products to improve product stability and shelf life.

Ethylenediaminetetraacetic acid disodium salt is employed in the textile industry to remove metal ions and enhance the dyeing process.
Ethylenediaminetetraacetic acid disodium salt is utilized in agriculture as a chelated micronutrient fertilizer.
In the construction industry, it improves the workability of cement and concrete mixtures.
Ethylenediaminetetraacetic acid disodium salt plays a vital role in a wide range of scientific, industrial, and medical applications, thanks to its versatile chelation properties.

In the automotive industry, Ethylenediaminetetraacetic acid disodium salt is added to automotive cooling systems as a corrosion inhibitor to protect engine components from metal-induced corrosion and scale buildup.
Ethylenediaminetetraacetic acid disodium salt is used in the preparation of laboratory reagents and buffers for biochemical and molecular biology research to ensure the accuracy of experiments.
Ethylenediaminetetraacetic acid disodium salt is employed in the mining and metallurgy industry to assist in the separation of valuable minerals from ore by binding to and facilitating the removal of unwanted metal ions.

Ethylenediaminetetraacetic acid disodium salt finds application in the electronics industry for cleaning semiconductor surfaces and preventing metal ion contamination during manufacturing.
In the water treatment field, Ethylenediaminetetraacetic acid disodium salt is utilized to sequester metal ions that can lead to the formation of scale deposits and reduce the efficiency of water systems.
Ethylenediaminetetraacetic acid disodium salt plays a role in the development of nanomaterials and nanoparticles, contributing to advancements in nanotechnology and materials science.

Ethylenediaminetetraacetic acid disodium salt is used in analytical chemistry as a complexing agent to determine the concentration of metal ions in environmental samples, such as water and soil.
Ethylenediaminetetraacetic acid disodium salt is employed in the cosmetics and personal care industry to maintain the stability and quality of various products, including creams, lotions, and shampoos.
In the construction sector, Ethylenediaminetetraacetic acid disodium salt is used to enhance the workability of cement and concrete mixtures, improving their performance and durability.
Ethylenediaminetetraacetic acid disodium salt is a key ingredient in certain veterinary medications, ensuring the safety and effectiveness of these pharmaceutical products.

Ethylenediaminetetraacetic acid disodium salt is used in the oil and gas industry to control the buildup of scale deposits in pipelines and equipment, which can obstruct oil flow.

Ethylenediaminetetraacetic acid disodium salt contributes to the preservation of archaeological artifacts, protecting them from metal corrosion and environmental degradation.
In the pulp and paper industry, it serves as a metal ion control agent to maintain paper quality and prevent discoloration during production.
Ethylenediaminetetraacetic acid disodium salt is utilized in the photography industry to stabilize photographic development solutions, preventing unwanted precipitation.

Ethylenediaminetetraacetic acid disodium salt plays a role in soil remediation efforts by assisting in the removal of heavy metal contaminants from polluted soil.
Ethylenediaminetetraacetic acid disodium salt is added to some cleaning products and detergents to enhance their effectiveness in removing mineral deposits, such as limescale.
In agriculture, Ethylenediaminetetraacetic acid disodium salt is used as a micronutrient fertilizer to deliver essential metals to plants in a form that is readily accessible.

Ethylenediaminetetraacetic acid disodium salt finds application in the food and beverage industry as a sequestrant to maintain the quality of processed foods and prevent undesirable color changes.
Ethylenediaminetetraacetic acid disodium salt is employed in the automotive radiator repair industry to remove mineral deposits and improve the cooling system's efficiency.
Ethylenediaminetetraacetic acid disodium salt is used as a stabilizing agent in the formulation of certain eye drops and ointments, ensuring their safety and efficacy.
In water softening systems, Ethylenediaminetetraacetic acid disodium salt is used to replace hard water ions with sodium ions, reducing the effects of hard water on appliances and plumbing.

Ethylenediaminetetraacetic acid disodium salt is applied in chemical analysis as a masking agent to selectively protect specific metal ions from interference during analysis.
Ethylenediaminetetraacetic acid disodium salt can be used to adjust the pH of solutions and maintain the desired pH range in various chemical processes.
Ethylenediaminetetraacetic acid disodium salt is utilized in laboratory settings to chelate metal ions in samples, preventing their interference with analytical techniques.
The versatile chelation properties of Ethylenediaminetetraacetic acid disodium salt continue to make it an indispensable chemical in numerous scientific, industrial, and environmental applications.



DESCRIPTION


Ethylenediaminetetraacetic acid disodium salt, often abbreviated as Ethylenediaminetetraacetic acid disodium salt, is a chemical compound with the molecular formula C10H14N2Na2O8.
Ethylenediaminetetraacetic acid disodium salt is a synthetic organic compound derived from ethylenediamine and acetic acid.
Ethylenediaminetetraacetic acid disodium salt is a chelating agent, which means it can form stable complexes with metal ions by coordinating with their positively charged ions.

Ethylenediaminetetraacetic acid disodium salt, also known as Ethylenediaminetetraacetic acid disodium salt, is a synthetic organic compound.
Ethylenediaminetetraacetic acid disodium salt is derived from ethylenediamine and acetic acid through a series of chemical reactions.

Ethylenediaminetetraacetic acid disodium salt has a white, crystalline appearance and is water-soluble.
The chemical formula of Ethylenediaminetetraacetic acid disodium salt is C10H14N2Na2O8, indicating its composition of carbon, hydrogen, nitrogen, sodium, and oxygen atoms.

Ethylenediaminetetraacetic acid disodium salt is a chelating agent, meaning it can form stable complexes with metal ions.
Ethylenediaminetetraacetic acid disodium salt can bind to metal ions by coordinating with their positively charged ions.
In analytical chemistry, Ethylenediaminetetraacetic acid disodium salt serves as a titrant in complexometric titrations to determine metal ion concentrations.
In the food and beverage industry, Ethylenediaminetetraacetic acid disodium salt is used as a food additive (E385) to preserve product color and flavor.

Ethylenediaminetetraacetic acid disodium salt can prevent the oxidation of food components by binding to metal ions that catalyze oxidation reactions.
Ethylenediaminetetraacetic acid disodium salt is used in the pharmaceutical industry as a stabilizing agent and preservative in some medications.

In the cosmetics and personal care sector, Ethylenediaminetetraacetic acid disodium salt is utilized in various products as a stabilizer.
Medical applications include the use of Ethylenediaminetetraacetic acid disodium salt in chelation therapy to treat heavy metal poisoning.

Ethylenediaminetetraacetic acid disodium salt is also employed as an anticoagulant in blood collection tubes to prevent clotting.
In the detergents and cleaning industry, Ethylenediaminetetraacetic acid disodium salt enhances the performance of laundry detergents by binding to metal ions that can interfere with the cleaning process.
Ethylenediaminetetraacetic acid disodium salt plays a crucial role in water treatment by sequestering and removing metal ions to prevent contamination.
Ethylenediaminetetraacetic acid disodium salt is an odorless and tasteless substance.
Ethylenediaminetetraacetic acid disodium salt is highly soluble in water, resulting in easy preparation of aqueous solutions.

Ethylenediaminetetraacetic acid disodium salt is considered safe for use in many applications when used as directed.
Its ability to form stable metal complexes makes it a valuable tool for analytical chemistry.
Ethylenediaminetetraacetic acid disodium salt is an important component in the preservation of certain foods and beverages.

Its presence in cosmetics and pharmaceuticals helps maintain product quality and stability.
Chelation therapy using Ethylenediaminetetraacetic acid disodium salt can be an effective treatment for heavy metal poisoning.
In the detergent industry, it ensures that laundry products effectively remove stains and soils.

Ethylenediaminetetraacetic acid disodium salt, with its versatile applications, continues to be a valuable chemical compound in various fields.
The consistent use of Ethylenediaminetetraacetic acid disodium salt is essential in maintaining the quality and safety of products in which it is employed.



PROPERTIES


Chemical Formula: C10H14N2Na2O8
Molar Mass: Approximately 372.24 g/mol
Appearance: White, crystalline powder
Solubility: Highly soluble in water
Melting Point: Decomposes at high temperatures
Density: 1.01 g/cm³ (approximate)
pH Level: Typically, a 0.1 M solution of Ethylenediaminetetraacetic acid disodium salt has a pH of around 4.0 to 5.0.
Odor: Odorless
Taste: Tasteless
Hygroscopic: It can absorb moisture from the air.



FIRST AID


Inhalation:

If Ethylenediaminetetraacetic acid disodium salt dust or particles are inhaled and respiratory distress occurs, immediately move the affected person to an area with fresh air.
Keep the person calm and encourage them to breathe slowly and deeply.
If breathing difficulties persist or worsen, seek medical attention promptly.


Skin Contact:

In case of skin contact with Ethylenediaminetetraacetic acid disodium salt, remove contaminated clothing and rinse the affected area thoroughly with copious amounts of water for at least 15 minutes.
Use a mild soap if available to wash the skin gently.
If irritation or redness persists, seek medical attention.
Contaminated clothing should be removed and washed before reuse.


Eye Contact:

If Ethylenediaminetetraacetic acid disodium salt comes into contact with the eyes, rinse the affected eye(s) gently but thoroughly with lukewarm water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.
Seek immediate medical attention, even if there is no initial discomfort or redness.


Ingestion:

If Ethylenediaminetetraacetic acid disodium salt is ingested accidentally, do not induce vomiting unless directed to do so by medical professionals.
Rinse out the mouth with water if the substance has been swallowed.
Seek immediate medical attention or contact a poison control center.
Provide them with as much information as possible about the ingestion, including the amount ingested and the individual's weight.


General First Aid:

If any symptoms of exposure or irritation occur, such as difficulty breathing, skin irritation, eye irritation, or other discomfort, seek medical attention promptly.
Provide medical personnel with safety data sheets (SDS) or other relevant information about Ethylenediaminetetraacetic acid disodium salt for proper treatment guidance.
Keep contaminated clothing and personal protective equipment (PPE) separate from other items to avoid further contamination.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
When working with Ethylenediaminetetraacetic acid disodium salt, wear appropriate personal protective equipment, including safety goggles or a face shield, chemical-resistant gloves, and a lab coat or protective clothing.

Ventilation:
Use adequate ventilation systems, such as fume hoods or local exhaust, to minimize exposure to airborne particles and dust.

Avoid Inhalation:
Avoid breathing in dust, vapors, or aerosols.
Use respiratory protection (e.g., N95 respirators) if working with fine powders or in poorly ventilated areas.

Prevent Skin and Eye Contact:
Prevent skin and eye contact by wearing suitable protective gear.
In case of accidental contact, follow first aid procedures.

Use Caution with Open Flames:
Do not use open flames, as Ethylenediaminetetraacetic acid disodium salt may produce hazardous fumes or gases when heated.

Avoid Eating, Drinking, or Smoking:
Do not eat, drink, or smoke in areas where Ethylenediaminetetraacetic acid disodium salt is handled.
Wash hands thoroughly after handling, especially before eating or drinking.


Storage:

Container:
Store Ethylenediaminetetraacetic acid disodium salt in well-sealed, labeled containers that are specifically designed for chemical storage.
Containers should be made of compatible materials, such as glass or plastic.

Temperature:
Store the chemical in a cool, dry place, away from direct sunlight, heat sources, and temperature extremes.

Moisture Control:
Protect the substance from moisture by keeping the containers tightly closed.
Consider using desiccants to maintain a low-humidity environment.

Isolation:
Store Ethylenediaminetetraacetic acid disodium salt away from incompatible materials, such as strong acids, strong bases, and reactive metals, to prevent reactions.

Childproofing:
Keep the chemical out of reach of children and unauthorized personnel.

Fire Safety:
Store away from open flames, sparks, or sources of ignition.

Labeling:
Ensure that containers are clearly labeled with the product name, hazard warnings, and handling instructions.

Segregation:
Store Ethylenediaminetetraacetic acid disodium salt separately from food, beverages, and personal items to prevent contamination.

Shelf Life:
Be aware of the product's shelf life and adhere to expiration dates.
Dispose of expired or degraded material properly.

Spill Containment:
Have appropriate spill containment measures and cleanup materials readily available in case of accidental spills or leaks.



SYNONYMS


Disodium EDTA
Sodium EDTA
Edetate disodium
Ethylenediaminetetraacetate disodium salt
Edathamil disodium
Disodium ethylene-diamine-tetraacetate
Edetic acid disodium salt
Disodium salt of EDTA
Sodium ethylenediaminetetraacetate
Disodium edetate
Sodium ethylenediaminetetraacetate dihydrate
EDTA Na2
Edetic acid sodium salt
Ethylenediaminetetraacetic acid disodium salt dihydrate
Sequestrene sodium
Titriplex II
Versene disodium
Edathamil disodium salt
Edetic acid disodium
Ethylenediaminetetraacetic acid sodium salt
Disodium ethylenediaminetetraacetate dihydrate
Sequestrene Na2
Tetrasodium EDTA
Titriplex III
Versene disodium salt
Edathamil disodium salt
Sodium edetate
Sodium ethylenediaminetetraacetate
Disodium ethylenediaminetetraacetate
Edetic acid sodium salt
Sodium diethylenetriaminepentaacetate
Edetate sodium
Disodium ethylene diamine tetraacetate
Edetate disodium salt
Sodium ethylenediaminetetracetate
Disodium edathamil
Disodium ethylenediaminetetraacetate dihydrate
Sodium EDTA dihydrate
Disodium versenate
Sodium versenate
Diethylenetriamine pentaacetate disodium salt
Disodium diethylenetriaminepentaacetate
Tetrasodium ethylenediaminetetraacetate
Disodium ethylenediaminetetraacetate dihydrate
Sodium diethylenetriamine pentaacetate
Ethylenediaminetetraacetate disodium salt hydrate
Diethylenetriaminepentaacetate disodium
Sodium edetate dihydrate
Disodium ethylenediamine tetraacetate
Edetate disodium dihydrate
EDTA Na2
Ethylenebis(iminodiacetic acid) disodium salt
Ethylenediamine-N,N,N',N'-tetraacetic acid disodium salt
Disodium ethylenediamine-N,N,N',N'-tetraacetate
Edathamil disodium
Sodium ethylenediaminetetraacetate dihydrate
Diethylenetriamine pentaacetic acid disodium salt
Disodium edetate dihydrate
Sodium diethylenetriamine pentaacetate dihydrate
Disodium diethylenetriaminepentaacetate
Ethylenediaminetetraacetate sodium salt dihydrate
Disodium ethylenediaminetetraacetic acid dihydrate
Ethylenediaminetetraacetic acid disodium salt dihydrate
Disodium versenate dihydrate
Sodium versenate dihydrate
Diethylenetriaminepentaacetate disodium salt dihydrate
Sodium ethylenediaminetetraacetate dihydrate
Edetic acid disodium salt dihydrate
Diethylenetriamine pentaacetic acid sodium salt
Disodium diethylenetriaminepentaacetate dihydrate
Ethylenediaminetetraacetic acid disodium salt hydrate
Disodium ethylenediaminetetraacetate dihydrate hydrate
Sodium diethylenetriamine pentaacetate dihydrate hydrate
Edetate disodium dihydrate hydrate
Ethylenebis(iminodiacetic acid) disodium salt dihydrate


ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT
Ethylenediaminetetraacetic Acid Disodium Salt is a sequestrant and chelating agent whose complete name is disodium ethylenediamine tetraacetate.
Ethylenediaminetetraacetic Acid Disodium Salt occurs as a white crystalline, odorless powder with a slightly acidic taste.


CAS Number: 6381-92-6/139-33-3
EC Number: 205-358-3
MDL Number: MFCD00070672
Molecular Formula: C10H14N2Na2O8


Ethylenediaminetetraacetic Acid Disodium Salt is a nonhygroscopic powder that is colorless, odorless, and tasteless at recommended use levels.
Ethylenediaminetetraacetic Acid Disodium Salt is a 1% solution has a ph of 4.3–4.7.
Ethylenediaminetetraacetic Acid Disodium Salt is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.


Ethylenediaminetetraacetic Acid Disodium Salts are more stable than edetic acid.
However, Ethylenediaminetetraacetic Acid Disodium Salt loses water of crystallization when heated to 120°C.
Aqueous solutions of disodium edetate may be sterilized by autoclaving, and should be stored in an alkali-free container.
Ethylenediaminetetraacetic Acid Disodium Salt is hygroscopic and is unstable when exposed to moisture.


Ethylenediaminetetraacetic Acid Disodium Salt should be stored in a well-closed container in a cool, dry place.
Ethylenediaminetetraacetic Acid Disodium Salt is the disodium salt form of edetate, a heavy metal chelating agent.
Ethylenediaminetetraacetic Acid Disodium Salt, a heavy metal antagonist, chelates divalent and trivalent metals, forming soluble stable complexes.
Ethylenediaminetetraacetic Acid Disodium Salt inhibits enzymes, such as metalloproteases, that require divalent cations for activity.


Ethylenediaminetetraacetic Acid Disodium Salt is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in many industrial and personal care products.
Ethylenediaminetetraacetic Acid Disodium Salt, dihydrate is a chelating agent for metal ions in aqueous solution like Fe3+, Co2+, Fe2+, Mn2+, Ca2+, and Mg2+.
Ethylenediaminetetraacetic Acid Disodium Salt is a nonhygroscopic powder that is colorless, odorless, and tasteless at recommended use levels.


Ethylenediaminetetraacetic Acid Disodium Salt is a 1% solution has a ph of 4.3–4.7.
Ethylenediaminetetraacetic Acid Disodium Salt's function is comparable to that of disodium calcium edta.
Ethylenediaminetetraacetic Acid Disodium Salt is an organic sodium salt that is the anhydrous form of the disodium salt of ethylenediaminetetraacetic acid (EDTA).


Ethylenediaminetetraacetic Acid Disodium Salt has been in seed germination trials of plant species and in protein extraction from Moss, Physcomitrella paten.
Ethylenediaminetetraacetic Acid Disodium Salt is an aminopolycarboxylic acid and a hexadentate ligand.
Ethylenediaminetetraacetic Acid Disodium Salt chelates with metal ions, especially with cations to form an octahedral complex.


Ethylenediaminetetraacetic Acid Disodium Salt is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia.
Ethylenediaminetetraacetic Acid Disodium Saltis produced as several salts, e.g. ethylenediaminetetra-acetic acid disodium salt (EDTAS).
Ethylenediaminetetraacetic Acid Disodium Salt is soluble in Aqueous Base (Slightly), Water (Sparingly, Sonicated).



USES and APPLICATIONS of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
Ethylenediaminetetraacetic Acid Disodium Salt is a sterile chelating reagent.
Ethylenediaminetetraacetic Acid Disodium Salt is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Ethylenediaminetetraacetic Acid Disodium Salt is used in the following products: washing & cleaning products, coating products, adhesives and sealants, biocides (e.g. disinfectants, pest control products), fillers, putties, plasters, modelling clay, polishes and waxes, non-metal-surface treatment products, metal surface treatment products, air care products, textile treatment products and dyes and photo-chemicals.


Ethylenediaminetetraacetic Acid Disodium Salt is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids) and outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).


Release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and industrial abrasion processing with high release rate (e.g. sanding operations or paint stripping by shot-blasting).


Other release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).


Ethylenediaminetetraacetic Acid Disodium Salt can be found in complex articles, with no release intended: vehicles, machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and electrical batteries and accumulators.


Ethylenediaminetetraacetic Acid Disodium Salt can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture), metal (e.g. cutlery, pots, toys, jewellery), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), rubber (e.g. tyres, shoes, toys), wood (e.g. floors, furniture, toys) and plastic (e.g. food packaging and storage, toys, mobile phones).


Ethylenediaminetetraacetic Acid Disodium Salt is used in the following products: laboratory chemicals.
Ethylenediaminetetraacetic Acid Disodium Salt is used in the following areas: formulation of mixtures and/or re-packaging and mining.
Ethylenediaminetetraacetic Acid Disodium Salt is used for the manufacture of: chemicals.


Release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid and of substances in closed systems with minimal release.
Other release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Ethylenediaminetetraacetic Acid Disodium Salt is used in the following products: laboratory chemicals and cosmetics and personal care products.
Ethylenediaminetetraacetic Acid Disodium Salt has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt can occur from industrial use: formulation of mixtures and formulation in materials.
Ethylenediaminetetraacetic Acid Disodium Salt is used in the following areas: mining and building & construction work.


Ethylenediaminetetraacetic Acid Disodium Salt is used for the manufacture of: chemicals and mineral products (e.g. plasters, cement).
Release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt can occur from industrial use: as processing aid, in processing aids at industrial sites, in the production of articles and of substances in closed systems with minimal release.


Other release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt can occur from industrial use: manufacturing of the substance, formulation of mixtures and as an intermediate step in further manufacturing of another substance (use of intermediates).
Ethylenediaminetetraacetic Acid Disodium Salt also acts as a food additive.


Ethylenediaminetetraacetic Acid Disodium Salt is used to control the reaction of trace metals to include calcium and magnesium with other organic and inorganic components in food to prevent deterioration of color, texture, and development of precipitates and to prevent oxidation.
Ethylenediaminetetraacetic Acid Disodium Salt's function is comparable to that of disodium calcium edta.


Disodium Dihydrogen Ethylenediaminetetraacetate Solution is generally immediately available in most volumes.
High purity, submicron and nanopowder forms may be considered.
American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.


Ethylenediaminetetraacetic Acid Disodium Salt is used in detergents, liquid soap, shampoo, agricultural chemicals, fixer solution for development of color film, water cleaner, pH modifier.
When stating the redox reaction for the polymerization of butyl benzene rubber, Ethylenediaminetetraacetic Acid Disodium Salt is used as part of activator for the control of polymerization speed.


Ethylenediaminetetraacetic Acid Disodium Salt is widely used in textile industry.
Usually Ethylenediaminetetraacetic Acid Disodium Salt is applied to dissolve limescale.
Ethylenediaminetetraacetic Acid Disodium Salt is applied in textile industry, pulp and paper industry and also in chelation therapy.


In cosmetics, Ethylenediaminetetraacetic Acid Disodium Salt acts as a sequestering agent.
Ethylenediaminetetraacetic Acid Disodium Salt acts as a corrosion inhibitor to carbon steel in the industries.
Ethylenediaminetetraacetic Acid Disodium Salt is used as a preservative used in concentrations of 0.1 to 0.5 percent.
Ethylenediaminetetraacetic Acid Disodium Salt is a sequestrant and chelating agent whose complete name is disodium ethylenediamine tetraacetate.


Ethylenediaminetetraacetic Acid Disodium Salt is used to control the reaction of trace metals to include calcium and magnesium with other organic and inorganic components in food to prevent deterioration of color, texture, and development of precipitates and to prevent oxidation.
Ethylenediaminetetraacetic Acid Disodium Salt is widely used in textile industry.
Usually applied to dissolve limescale.


Ethylenediaminetetraacetic Acid Disodium Salt has a wide range of coordination properties, and can form stable chelates with almost all metal ions.
Ethylenediaminetetraacetic Acid Disodium Salt provides the possibility to determine elements widely (better than acid-base and precipitation methods).
Ethylenediaminetetraacetic Acid Disodium Salt chelating agents are widely used in water treatment, dyeing, oil cleaning, etc.


Ethylenediaminetetraacetic Acid Disodium Salt is used as a
biological buffer, Chelation/Complexation reagent.
Ethylenediaminetetraacetic Acid Disodium Salt is used widely in topical, oral, and parenteral pharmaceutical formulations; it is used extensively in cosmetic and food products.


Ethylenediaminetetraacetic Acid Disodium Salt is used in a greater number and variety of pharmaceutical formulations than edetic acid.
Ethylenediaminetetraacetic Acid Disodium Salt is poorly absorbed from the gastrointestinal tract and is associated with few adverse effects when used as excipients in pharmaceutical formulations.


Ethylenediaminetetraacetic Acid Disodium Salt is also used as a water softener as it will chelate calcium and magnesium ions present in hard water.
Ethylenediaminetetraacetic Acid Disodium Salt is also used therapeutically as an anticoagulant as it will chelate calcium and prevent the coagulation of blood in vitro.
Concentrations of 0.1% w/v are used in small volumes for hematological testing and 0.3% w/v in transfusions.


Ethylenediaminetetraacetic Acid Disodium Salt is used as chelating agent for metals and as pharmaceutic aid (chelating agent).
Ethylenediaminetetraacetic Acid Disodium Salt is used as preservative in cosmetic products.
Ethylenediaminetetraacetic Acid Disodium Salt is also used as anticoagulant.
Ethylenediaminetetraacetic Acid Disodium Salt is used as a chelating agent (metal); pharmaceutic aid (chelating agent).


Ethylenediaminetetraacetic Acid Disodium Salt is applied in textile industry, pulp and paper industry and also in chelation therapy.
In cosmetics, Ethylenediaminetetraacetic Acid Disodium Salt acts as a sequestering agent.
Ethylenediaminetetraacetic Acid Disodium Salt acts as a corrosion inhibitor to carbon steel in the industries.
Ethylenediaminetetraacetic Acid Disodium Salt also acts as a food additive.


Ethylenediaminetetraacetic Acid Disodium Salt has also been used in lysis and vacuole buffer for the isolation of vacuoles from Petunia petals.
Ethylenediaminetetraacetic Acid Disodium Salt is used as a chelator of divalent cations.
Ethylenediaminetetraacetic Acid Disodium Salt inhibits enzymes, such as metalloproteases, that require divalent cations for activity.


Ethylenediaminetetraacetic Acid Disodium Salt uses and applications include: Chelating agent in cosmetics, pharmaceuticals, water treatment, textiles, soapsdetergents, electroless copper plating, polymer production, disinfectants, pulppaper, enhanced oil recovery, metal cleaningprotection; scale inhibitor (boiler water treatment); textileleather processing auxiliaries; antioxidant for cosmetics; prevents metal-catalyzed oxidative breakdown; preservative, preservative synergist, antioxidant, stabilizer, chelant, sequestrant in foods; hog scald agent; anticoagulant; pharmaceutic aid; viscous control agent; chelating agent in food-contact paperpaperboard manufacturing; in cellophane for food packaging; chelating agentsequestrant in lubricants for incidental food-contact use; in food packaging adhesives; in surfactant lubricants for manufacturing of food-contact metallic articles.


Ethylenediaminetetraacetic Acid Disodium Salt is widely used as a chelating agent in a variety of pharmaceutical preparations, including mouthwashs, ophthalmic preparations and topical preparations.
Ethylenediaminetetraacetic Acid Disodium Salt is also used as a stabilizer for various emulsions.
Ethylenediaminetetraacetic Acid Disodium Salt is used in several industrial applications attributing to its high ability to bind to most of metal cations.


Ethylenediaminetetraacetic Acid Disodium Salt is used as chelating agents in cosmetic formulations.
EDTAS is a preservative, sequestrant, and stabilizer in foods.
EDTA is added to ascorbic acid-disodium benzoate containing soft drinks to mitigate the formation of benzene.
EDTA and its salts are used as a component in the production of food-contact paper and paperboard.


EDTAS is permitted in the feed and drinking water of animals and/or for the treatment of food-producing animals.
In the textile industry, EDTA and its salts prevent metal ion impurities from changing colors of dyed products.
In the pulp and paper industry, EDTA and its salts inhibit the ability of metal ions from catalyzing the disproportionation of hydrogen peroxide (a typical bleaching agent).


EDTA is used in synthetic rubber manufacture.
EDTA is also used as a corrosion inhibitor to carbon steel in the industries.
Ethylenediaminetetraacetic Acid Disodium Salt chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests.
Ethylenediaminetetraacetic Acid Disodium Salt enhances the antibacterial activity of lysozyme.


Ethylenediaminetetraacetic Acid Disodium Salt is used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease.
Ethylenediaminetetraacetic Acid Disodium Salt chelation therapy may also protect from oxidative damage during blood and lipid peroxidation in liver fibrosis.


Ethylenediaminetetraacetic Acid Disodium Salt is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in many industrial and personal care products.
Ethylenediaminetetraacetic Acid Disodium Salt is used as a stabilizer for various emulsions.


Ethylenediaminetetraacetic Acid Disodium Salt is added to foods and personal care products.
Ethylenediaminetetraacetic Acid Disodium Salt is used in aqueous solutions with other reagents and inert materials for the preparation of cleaning mixtures and poultices to be applied to stone surfaces and frescoes.


Ethylenediaminetetraacetic Acid Disodium Salt, for its property of complexing calcium within crusts and for its good solubility (better than tetrasodium salt), is used in the AB 57 poultice (I.C.R. formulation - Rome).
Ethylenediaminetetraacetic Acid Disodium Salt is besides a strong chelating agent of a great many metallic cations, as iron and copper; this property can be utilized to remove stains of rust or copper green from stone surfaces, wood, plasters, etc…


-Personal care & skincare products:
Binding to free metal ions and serves as a purifying agent and preservative.
-Shampoos and soaps:
Reducing the "hardness" (or presence of metal cations) in tap water so that other ingredients can work to cleanse more efficiently.


-Laundry detergents:
To soften water that comes into contact with it so the other active ingredients can cleanse better.
-Textiles:
Preventing the discolouring of dyed fabrics by removing harmful free metal ions and getting rid of residue left on industrial equipment.


-Agriculture Fertilizers:
Ethylenediaminetetraacetic Acid Disodium Salt is mainly used as foliar fertilizers, water-soluble fertilizers to supply trace elements for vegetables, crops, and fruits.
-Foods:
Ethylenediaminetetraacetic Acid Disodium Salt is used for chelating metal ions, removing heavy metals of foods.
EDTA metal salts e.g. Ca, Zn, Fe, are used for supplying micronutrients for human.


-Cosmetic Uses of Ethylenediaminetetraacetic Acid Disodium Salt:
*chelating agents
*viscosity controlling agents


-Biochem/physiol Actions of Ethylenediaminetetraacetic Acid Disodium Salt:
Ethylenediaminetetraacetic Acid Disodium Salt has the ability to block the binding of vasoactive intestinal peptide to macrophage membranes.
Ethylenediaminetetraacetic Acid Disodium Salt is mainly used in the purification of protein, to remove divalent cations and also to prevent protease activity.


-Pharmaceutical Applications of Ethylenediaminetetraacetic Acid Disodium Salt:
Ethylenediaminetetraacetic Acid Disodium Salt is used as a chelating agent in a wide range of pharmaceutical preparations, including mouthwashes, ophthalmic preparations, and topical preparations, typically at concentrations between 0.005 and 0.1% w/v.
Ethylenediaminetetraacetic Acid Disodium Salt forms stable water-soluble complexes (chelates) with alkaline earth and heavy-metal ions.
The chelated form of Ethylenediaminetetraacetic Acid Disodium Salt has few of the properties of the free ion, and for this reason chelating agents are often described as ‘removing’ ions from solution, a process known as sequestering.
The stability of the metal–edetate complex is dependent on the metal ion involved and the pH.


-Veterinary Drugs and Treatments:
Ethylenediaminetetraacetic Acid Disodium Salt is a chelating agent that is also used to stop the melting effect of collagenases and proteases on the cornea.
Ethylenediaminetetraacetic Acid Disodium Salt is useful in halting melting through inhibition of matrix metalloproteinases, but is not felt to be useful for melting caused by infectious agents.
As the effect of Ethylenediaminetetraacetic Acid Disodium Salt on metalloproteinases is reversible, it must be administered several times daily to be effective.


-Industrial Applications of Ethylenediaminetetraacetic Acid Disodium Salt:
Ethylenediaminetetraacetic Acid Disodium Salt is used in cleaners, detergent, fertilizers, fixer solution for development of colour film, water cleaner and pH modifier.
Ethylenediaminetetraacetic Acid Disodium Salt is also used in redox reaction for the polymerization of butyl benzene rubber.
Ethylenediaminetetraacetic Acid Disodium Salt is used as part of activator for the control of polymerization speed.


-Personal Care Applications of Ethylenediaminetetraacetic Acid Disodium Salt:
Ethylenediaminetetraacetic Acid Disodium Salt is used in Cosmetics to increase effectiveness and improve stability of bar and solid soaps, bath preparations; creams, oils, hair care products and many other personal care formulations.
-Application of Ethylenediaminetetraacetic Acid Disodium Salt:
*Surfactants & Emulsifiers



FUNCTIONS OF ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
*Preservative
*Scale Inhibitor
*Stabilizer
*Lubricant



INDUSTRY:
*Cosmetic
*Plating
*Pharmaceutical
*Water Treatment
*Textiles
*Adhesives
*Detergent



INCOMPATIBILITIES OF ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
Ethylenediaminetetraacetic Acid Disodium Salt behaves as a weak acid, displacing carbon dioxide from carbonates and reacting with metals to form hydrogen.
Ethylenediaminetetraacetic Acid Disodium Salt is incompatible with strong oxidizing agents, strong bases, metal ions, and metal alloys.



MANUFACTURING PROCESS OF ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
10 mols of ethylene diamine as a 30% aqueous solution and 4 mols of solid caustic soda are placed in a steam heated kettle supplied with an agitator.
8 mols of sodium cyanide as a concentrated water solution (about 30%) are added and the solution heated to 60°C.
About a 10 inch vacuum is applied to bring the liquid to incipient boiling.

Formaldehyde (7.5 mols of 37% to 40% aqueous solution) is slowly added, the temperature being held at 60°C, and the solution vigorously stirred.
Then, when the evolution of ammonia has substantially stopped, an additional 8 mols of sodium cyanide, followed by 8 mols of formaldehyde are added as before.
This is continued until 40 mols of cyanide and 40 mols of formaldehyde have been added.

Then at the end about 2 mols more of formaldehyde are added, making 42 mols in all, to remove any last traces of cyanide.
About 8 to 10 hours are required to complete the reaction.
The resulting product, referred to herein as the crude reaction product, is essentially an aqueous solution of the sodium salt of ethylene diamine tetracetic acid.

To 1,000 g of the crude reaction product are added 264 g of ethylene diamine tetracetic acid.
The mixture is preferably heated to incipient boiling to increase the rate of reaction, and then the mixture is allowed to cool and crystallize.
The crystals formed are filtered off, washed with the smallest possible amount of ice water, and dried to a constant weight, which is 452 g.

A representative sample of the product so prepared showed, upon analysis, 13.26% sodium against a theoretical of 13.70% for the disodium salt.
The dialkali salt has a pH of about 5.3 and behaves like a weak acid, displacing CO2 from carbonates and reacting with metals to form hydrogen.
Ethylenediaminetetraacetic Acid Disodium Salt is a white crystalline solid.



PRODUCTION METHODS OF ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
Ethylenediaminetetraacetic Acid Disodium Salt may be prepared by the reaction of edetic acid and sodium hydroxide.



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
Formula: [CH2N(CH2COOH)CH2COONa]2·2H2O
Appearance: white crystals
Assay: 99% min.
Specific gravity: 0.8 - 1.1 kg/l at 20°C
pH: 4,5-5 in 10% aqueous solution
Appearance: white crystalline powder (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in: water, 1e+006 mg/L @ 25 °C (est)
Insoluble in: alcohol
Form: powder
Colour: white
Odour: product specific
Odour threshold:
not determined
pH value: 4 - 5 (DIN 19268)
Melting point: 248 °C (dec.)(lit.)
Boiling point: >100 °C
Density: 1.01 g/mL at 25 °C

vapor pressure: 0Pa at 25℃
storage temp.: 2-8°C
solubility: H2O: clear, colorless
form: solution
color: ≤5 (0.5 M)(APHA)
Water Solubility: Miscible with water.
BRN: 3822669
Stability: Hygroscopic
LogP: -4.3 at 25℃
Self ignition: not self-igniting
Test type: Spontaneous selfignition at room-temperature.
Temperature: > 400 °C Test type: Self-ignition at high
Pressure: 1.013,25 hPa temperatures.
No self ignition was observed up to (Method: Regulation
the specified temperature. 440/2008/EC, A.16)
Viscosity, dynamic:
Study scientifically not justified.
Viscosity, kinematic: not applicable, the product is a solid

Explosion hazard: Product is not explosive, however a dust explosion could result from an air / dust mixture.
Fire promoting properties: Based on its structural properties the product is not classified as oxidizing.
Other information:
Self heating ability: It is not a substance capable of spontaneous heating.
Minimum ignition energy: > 4 J (DIN EN 13821) (1.013,25 hPa, 20 °C)
Bulk density: approx. 950 kg/m3 (DIN ISO 697)
Surface tension: Based on chemical structure, surface activity is not to be expected.
Grain size distribution: particles < 100 µm approx. 29 %
particles < 10 µm approx. 1,2 %
particles < 4 µm approx. 0,2 %
Melting Point: >250°C (dec.)
Density: 1.01 g/mL at 25°C
InChI Key: ZGTMUACCHSMWAC-UHFFFAOYSA-L
Stability: Stable.
Molecular Formula: C₁₀H₁₄N₂Na₂O₈
Appearance: White to Off-White Solid
Melting Point: >250°C (dec.)
Molecular Weight: 336.21
Storage: 4°C, Hygroscopic
Solubility: Aqueous Base (Slightly), Water (Sparingly, Sonicated)
Stability: Hygroscopic



FIRST AID MEASURES of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Description of first aid measures:
Remove contaminated clothing.
*If inhaled:
Keep patient calm, remove to fresh air, seek medical attention.
*On skin contact:
Wash thoroughly with soap and water.
*On contact with eyes:
Wash affected eyes for at least 15 minutes under running water with eyelids held open.
*On ingestion:
Immediately rinse mouth and then drink 200-300 ml of water, seek medical attention.
-Indication of any immediate medical attention and special treatment needed:
*Treatment:
Treat according to symptoms, with no known specific antidote.



ACCIDENTAL RELEASE MEASURES of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Personal precautions, protective equipment and emergency procedures:
Use personal protective clothing.
-Environmental precautions:
Contain contaminated water/firefighting water.
Do not discharge into drains/surface waters/groundwater.
-Methods and material for containment and cleaning up:
*For small amounts:
Pick up with suitable appliance and dispose of.
*For large amounts:
Contain with dust binding material and dispose of.
Dispose of absorbed material in accordance with regulations.



FIRE FIGHTING MEASURES of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Extinguishing media:
*Suitable extinguishing media:
dry powder, foam
-Advice for fire-fighters:
*Further information:
Contaminated extinguishing water must be disposed of in accordance with official regulations.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Exposure controls:
--Personal protective equipment:
*Hand protection:
Chemical resistant protective gloves.
*Supplementary note:
Manufacturer's directions for use should be observed because of great diversity of types.
*Eye protection:
Safety glasses with side-shields (frame goggles)
-General safety and hygiene measures:
Wearing of closed work clothing is recommended.
No eating, drinking, smoking or tobacco use at the place of work.
Handle in accordance with good industrial hygiene and safety practice.



HANDLING and STORAGE of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Conditions for safe storage, including any incompatibilities:
*Suitable materials for containers:
Low density polyethylene (LDPE), glass, Paper/Fibreboard, High density polyethylene (HDPE)
-Further information on storage conditions:
Keep container tightly closed and dry; store in a cool place.



STABILITY and REACTIVITY of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Reactivity:
No hazardous reactions if stored and handled as prescribed/indicated.
*Corrosion to metals:
No corrosive effect on metal.
-Chemical stability:
The product is stable if stored and handled as prescribed/indicated.



SYNONYMS:
Disodium EDTA
Isodium dihydrogen ethylenediaminetetraacetate
Edetic acid disodium salt
EDTA disodium salt
(Ethylenedinitrilo)tetraacetic acid disodium salt
Disodium Edetate
Chelaplex
Chelaplex III
Chelaton III
Chelest 200
Chelest 2B-SD
Chelest 2BS
Chelest B; Clewat N
Clewat N 2
Complexon III
Disodium (Ethylenedinitrilo)tetraacetate
Disodium EDTA
Disodium Diacid Ethylenediaminetetraacetate
Disodium Dihydrogen Ethylenediaminetetraacetate
1,2-DIAMINOETHANE-N,N,N',N'-TETRA-ACETIC ACID DISODIUM SALT
1,2-DIAMINOETHANE-N,N,N',N'-TETRA-ACETIC ACID DISODIUM SALT 2H2O
4C EDTA
COMPLEXONE III
COMPLEXONE III(R)
DISODIUM DIHYDROGEN ETHYLENEDIAMINE TETRAACETATE
DISODIUM DIHYDROGEN ETHYLENEDIAMINETETRAACETATE DIHYDRATE
DISODIUM DIHYDROGEN ETHYLENEDIAMINETETRA-ACETIC DIHYDRATE
DISODIUM EDETATE
DISODIUM EDETATE DIHYDRATE
DISODIUM EDTA
DISODIUM ETHYLENEDIAMINETETRAACETATE
DISODIUM ETHYLENEDIAMINETETRAACETATE DIHYDRATE
Disodium ethylenediaminetetraacetic acid
DISODIUM (ETHYLENEDINITRILO)TETRAACETATE, DIHYDRATE
EDATHAMIL DISODIUM SALT DIHYDRATE
EDETATE DISODIUM
EDETATE DISODIUM, DIHYDRATE
EDETATE DISODIUM DIHYDROGEN, DIHYDRATE
EDETATE DISODIUM SALT DIHYDRATE
(Ethylenedinitrilo)tetraacetic acid disodium salt
EDTA disodium salt, EDTA-Na2
(Ethylenedinitrilo)tetraacetic Acid Disodium Salt
EDTA Disodium Salt; EDTA-Na2
Ethylenediamine-N,N,N',N'-tetraacetic Acid Disodium Salt
EDNRA
1,2-Diaminoethane-N,N,N',N'-tetra-acetic Acid Sisodium Salt
ETHYLENEBIS(IMINODIACETIC ACID)DISODIUM SALT
ETHYLENEDIAMINETETRAACETIC ACID, 2NA, DIHYDRATE
ETHYLENE DIAMINETETRA ACETIC ACID DISODIUM
ETHYLENEDIAMINE TETRAACETIC ACID DISODIUM DIHYDRATE
ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT
ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT-2-HYDRATE
ETHYLENEDIAMINE-N,N,N',N'-TETRAACETIC ACID DISODIUM SALT
ETHYLENEDIAMINETETRAACETATE DISODIUM SALT
(ETHYLENENDINITRILO)TETRAACETIC ACID, DISODIUM SALT, DIHYDRATE
(ETHYLENEDINITRILO)TETRAACETIC DISODIUM, DIHYDRATE
Disodium EDTA
Disodium dihydrogen ethylenediaminetetraacetate
Disodium edetate
Disodium ethylenediamine tetraacetate
Edetate disodium
Ethylenediaminetetraacetic acid, disodium salt (Ethylenedinitrilo) tetraacetic acid, sodium salt
Glycine, N,N-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt dihydrate
Chelaplex
Chelaplex III
Chelaton III
Chelest B
Disodium (Ethylenedinitrilo)tetraacetate
Disodium EDTA
Disodium Diacid Ethylenediaminetetraacetate
Disodium Dihydrogen Ethylenediaminetetraacetate
Disodium Edathamil
Disodium Edetate
Disodium Ethylenediamine-N,N,N',N'-tetraacetate
Disodium Ethylenediaminetetraacetate
Disodium Ethylenediaminetetraacetic Acid Salt
Disodium Sequestrene
Disodium Tetracemate
Disodium Versenate
Disodium Versene
EDTA Disodium Salt
Edathamil Disodium
Edetate Disodium
Endrate Disodium
Ethylenedinitrilotetraacetate Disodium
EDTA-2NA
DISODIUM EDTA
DISODIUM EDETATE
ETA;EDETATE DISODIUM
EDTA DISODIUM
EDTA DISODIUM SALT
TITRIPLEX III
DISODIUM ETHYLENEDIAMINETETRAACETATE
EDTA NA2
Ethylenediaminetetra-acetic acid disodium salt dihydrate
Edetate disodium dihydrate
Ethylenediaminetetraacetic acid, disodium salt, dihydrate
Kestranal 2S 2 H2O
Ethylenedinitrilotetra-acetic acid disodium salt dihydrate
Titriplex III
Kestranal 2S dihydrate
Edetic acid disodium salt dihydrate
Disodium dihydrogen ethylenediaminetetraacetate dihydrate




ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT (EDTA - 2NA)
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is used in several industrial applications attributing to its high ability to bind to most of metal cations.
EDTA is produced as several salts, e.g. Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na).
EDTA and Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na)'s salts are used as chelating agents in cosmetic formulations.

CAS: 139-33-3
MF: C10H14N2Na2O8
MW: 336.21
EINECS: 205-358-3

Synonyms
SEQUESTRENE NA2;SODIUM (DI) ETHYLENEDIAMINE TETRAACETATE DIHYDRATE;VERSENE NA, DIHYDRATE;VERSENE DISODIUM;WANKLYN'S EDTA;Ceftriaxone Impurity 21(EDTA Disodium);disodium ethylenediamintetraacetate;EDTA two sodium;Edetate disodium;139-33-3;EDTA disodium salt;Disodium edetate;Edta disodium;Titriplex III;Disodium EDTA;Disodium edta,anhydrous;Cheladrate;Ethylenediaminetetraacetic acid disodium salt;Disodium versene;Endrate disodium;Sodium versenate;Disodium salt of EDTA;Metaquest B;Kiresuto B;Chelaplex III;Chelest B;Diso-Tate;Komplexon III;Chelaton III;Clewat N;Versene NA;Triplex III;Chelaton 3;Disodium versenate;Edathamil disodium;Trilon BD;Versene Na2;Zonon D;Edetate disodium anhydrous;Dotite 2NA;Selekton B 2;Disodium sequestrene;Disodium tetracemate;Mavacid ED 4;Versonol 120;Disodium ethylenediaminetetraacetate;Chelest 200;Sequestrene sodium 2;Veresene disodium salt;Disodium EDTA dihydrate;Perma Kleer Di Crystals;Edetic acid disodium salt;Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt;Ethylenediaminetetraacetic acid, disodium salt;CCRIS 3658;E.D.T.A. disodique;EDTA-Na2;Disodium dihydrogen ethylenediaminetetraacetate;NSC 2760;EDTA disodium salt (anhydrous);Anhydrous disodium edetate;EINECS 205-358-3;Disodium ethylenediamine-N,N,N',N'-tetraacetate;Perma kleer 50 crystals disodium salt;UNII-8NLQ36F6MM;Disodium ethylenediaminetetraacetic acid;Edetate disodium, anhydrous;Ethylene diamine tetraacetic acid, disodium salt;Disodium (ethylenedinitrilo)tetraacetate;Edetic Acid, Disodium Salt;CBC 50152966
;DR-16133;Ethylenediaminetetraacetate, disodium salt;Disodium diacid ethylenediaminetetraacetate;MFCD00070672;AI3-18049;Disodium (ethylenedinitrilo)tetraacetic acid;Dinatrium ethylendiamintetraacetat;HSDB 8013;Trilon B;Disodium dihydrogen(ethylenedinitrilo)tetraacetate;Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, disodium salt;Endrate (TN);Disodium edathamil;6381-92-6;disodium 2-({2-[(carboxylatomethyl)(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetate;Tetracemate disodium;Na2-EDTA
;N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine) disodium salt;EC 205-358-3;Edta disodium salt anhydrous;8NLQ36F6MM;CHEBI:64734;Disodium N,N'-1,2-ethanediylbis(N-(carboxymethyl)glycine);ACETIC ACID, (ETHYLENEDINITRILO)TETRA-, DISODIUM SALT;NSC-2760;E.D.T.A. disodique [French];F 1 (VAN);ethylenediamine tetraacetic acid disodium salt;Dinatrium ethylendiamintetraacetat [Czech];Ethylenebis(iminodiacetic acid) disodium salt;disodium 2-((2-((carboxylatomethyl)(carboxymethyl)amino)ethyl(carboxymethyl)amino)acetate;(Ethylenedinitrilo)-tetraacetic acid disodium salt;Na2EDTA;0.5M Sodium EDTA;Disodium edetate (TN);Na2.EDTA;CHEMBL1749;DTXSID9027073;disodium ethylenediamine-tetraacetate;AKOS016370696;DB14600;SB40706;69772-70-9;E386;ethylenediaminetetracetic acid disodium salt;DB-042467;NS00078150;EN300-35828;ethylenediaminetetra-acetic acid disodium salt;D03945;P17519;J-007267;J-521348;Q4532977;disodium 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetate;Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, sodium salt (1:2);(Ethylenedinitrilo)tetraacetic acid disodium salt, EDTA disodium salt, EDTA-Na2;2-[2-(Carboxylatomethyl-(carboxymethyl)amino)ethyl-(carboxymethyl)amino]acetate disodium;disodium;2-[2-[carboxylatomethyl(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetate;DISODIUM 2-({2-[(CARBOXYLATOMETHYL)(CARBOXYMETHYL)AMINO]ETHYL(CARBOXYMETHYL)AMINO)ACETATE

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a preservative, sequestrant, and stabilizer in foods.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is added to ascorbic acid-disodium benzoate containing soft drinks to mitigate the formation of benzene.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) and its salts are used as a component in the production of food-contact paper and paperboard.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is permitted in the feed and drinking water of animals and/or for the treatment of food-producing animals.
In the textile industry, EDTA and Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na)'s salts prevent metal ion impurities from changing colors of dyed products.
In the pulp and paper industry, EDTA and Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na)'s salts inhibit the ability of metal ions from catalyzing the disproportionation of hydrogen peroxide (a typical bleaching agent).
EDTAS is used in synthetic rubber manufacture.

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is also used as a corrosion inhibitor to carbon steel in the industries.
As an anticoagulant, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) and tripotassium salts of EDTA are most commonly used.
An organic sodium salt that is the anhydrous form of the disodium salt of Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na).
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a calcium ion chelator, that has a low molecular mass of 292.24 Da.
​Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in many industrial and personal care products.

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na), also called EDTA acid after its own abbreviation, is an aminopolycarboxylic acid with the formula [CH2N(CH2CO2H)2]2.
This white, water-insoluble solid is widely used to bind to iron (Fe2+/Fe3+) and calcium ions (Ca2+), forming water-soluble complexes even at neutral pH.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is thus used to dissolve Fe- and Ca-containing scale as well as to deliver iron ions under conditions where its oxides are insoluble.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is available as several salts, notably disodium EDTA, sodium calcium edetate, and tetrasodium EDTA, but these all function similarly.

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) Chemical Properties
Melting point: 248 °C (dec.)(lit.)
Boiling point: >100 °C
Density: 1.01 g/mL at 25 °C
Vapor pressure: 0Pa at 25℃
Storage temp.: 2-8°C
Solubility H2O: clear, colorless
Form: solution
Color: ≤5 (0.5 M)(APHA)
Odor: at 100.00?%. odorless
Water Solubility: Miscible with water.
BRN: 3822669
Stability: Hygroscopic
LogP: -4.3 at 25℃
CAS DataBase Reference: 139-33-3(CAS DataBase Reference)
EPA Substance Registry System: Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) (139-33-3)
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) occurs as a white crystalline, odorless powder with a slightly acidic taste.

uses
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is an aminopolycarboxylic acid and a hexadentate ligand.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) chelates with metal ions, especially with cations to form an octahedral complex.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) enhances the antibacterial activity of lysozyme.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) chelation therapy may also protect from oxidative damage during blood and lipid peroxidation in liver fibrosis.

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a preservative used in concentrations of 0.1 to 0.5 percent.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a sequestrant and chelating agent whose complete name is disodium ethylenediamine tetraacetate.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a nonhygroscopic powder that is colorless, odorless, and tasteless at recommended use levels. A 1% solution has a ph of 4.3–4.7.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is used to control the reaction of trace metals to include calcium and magnesium with other organic and inorganic components in food to prevent deterioration of color, texture, and development of precipitates and to prevent oxidation.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na)'s function is comparable to that of disodium calcium edta.

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is widely used in textile industry. Usually applied to dissolve limescale.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is applied in textile industry, pulp and paper industry and also in chelation therapy.
In cosmetics, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) acts as a sequestering agent.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) acts as a corrosion inhibitor to carbon steel in the industries.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) also acts as a food additive.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) has been in seed germination trials of plant species and in protein extraction from Moss, Physcomitrella paten.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) has also been used in lysis and vacuole buffer for the isolation of vacuoles from Petunia petals.

Pharmaceutical Applications
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is used as a chelating agent in a wide range of pharmaceutical preparations, including mouthwashes, ophthalmic preparations, and topical preparations, typically at concentrations between 0.005 and 0.1% w/v.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) forms stable water-soluble complexes (chelates) with alkaline earth and heavy-metal ions.
The chelated form has few of the properties of the free ion, and for this reason chelating agents are often described as ‘removing’ ions from solution, a process known as sequestering.
The stability of the metal–edetate complex is dependent on the metal ion involved and the pH.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is also used as a water softener as it will chelate calcium and magnesium ions present in hard water.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is also used therapeutically as an anticoagulant as it will chelate calcium and prevent the coagulation of blood in vitro.
Concentrations of 0.1% w/v are used in small volumes for hematological testing and 0.3% w/v in transfusions.

Industrial Applications
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is used in cleaners, detergent, fertilizers, fixer solution for development of colour film, water cleaner and pH modifier.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is also used in redox reaction for the polymerization of butyl benzene rubber, it is used as part of activator for the control of polymerization speed.

Uses
Textiles and paper
In industry, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is mainly used to sequester (bind or confine) metal ions in aqueous solution.
In the textile industry, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) prevents metal ion impurities from modifying colours of dyed products.
In the pulp and paper industry, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) inhibits the ability of metal ions, especially Mn2+, from catalysing the disproportionation of hydrogen peroxide, which is used in chlorine-free bleaching.

Food
In a similar manner, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is added to some food as a preservative or stabiliser to prevent catalytic oxidative decolouration, which is catalysed by metal ions.

Water softener
The reduction of water hardness in laundry applications and the dissolution of scale in boilers both rely on Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) and related complexants to bind Ca2+, Mg2+, as well as other metal ions.
Once bound to Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na), these metal complexes are less likely to form precipitates or to interfere with the action of the soaps and detergents.
For similar reasons, cleaning solutions often contain Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na).
In a similar manner Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is used in the cement industry for the determination of free lime and free magnesia in cement and clinkers.

The solubilisation of Fe3+ ions at or below near neutral pH can be accomplished using EDTA.
This property is useful in agriculture including hydroponics.
However, given the pH dependence of ligand formation, EDTA is not helpful for improving iron solubility in above neutral soils.
Otherwise, at near-neutral pH and above, iron(III) forms insoluble salts, which are less bioavailable to susceptible plant species.

Manufacturing Process
10 mols of ethylene diamine as a 30% aqueous solution and 4 mols of solid caustic soda are placed in a steam heated kettle supplied with an agitator.
8 mols of sodium cyanide as a concentrated water solution (about 30%) are added and the solution heated to 60°C.
About a 10 inch vacuum is applied to bring the liquid to incipient boiling.
Formaldehyde (7.5 mols of 37% to 40% aqueous solution) is slowly added, the temperature being held at 60°C, and the solution vigorously stirred.
Then, when the evolution of ammonia has substantially stopped, an additional 8 mols of sodium cyanide, followed by 8 mols of formaldehyde are added as before.
This is continued until 40 mols of cyanide and 40 mols of formaldehyde have been added.
Then at the end about 2 mols more of formaldehyde are added, making 42 mols in all, to remove any last traces of cyanide.

About 8 to 10 hours are required to complete the reaction.
The resulting product, referred to herein as the crude reaction product, is essentially an aqueous solution of the sodium salt of ethylene diamine tetracetic acid.
To 1,000 g of the crude reaction product are added 264 g of ethylene diamine tetracetic acid.
The mixture is preferably heated to incipient boiling to increase the rate of reaction, and then the mixture is allowed to cool and crystallize.
The crystals formed are filtered off, washed with the smallest possible amount of ice water, and dried to a constant weight, which is 452 g.
A representative sample of the product so prepared showed, upon analysis, 13.26% sodium against a theoretical of 13.70% for the disodium salt.
The dialkali salt has a pH of about 5.3 and behaves like a weak acid, displacing CO2 from carbonates and reacting with metals to form hydrogen.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a white crystalline solid.

Synthesis
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) was first described in 1935 by Ferdinand Münz, who prepared the compound from ethylenediamine and chloroacetic acid.
Today, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is mainly synthesised from ethylenediamine (1,2-diaminoethane), formaldehyde, and sodium cyanide.
This route yields the tetrasodium Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na), which is converted in a subsequent step into the acid forms:

H2NCH2CH2NH2 + 4 CH2O + 4 NaCN + 4 H2O → (NaO2CCH2)2NCH2CH2N(CH2CO2Na)2 + 4 NH3
(NaO2CCH2)2NCH2CH2N(CH2CO2Na)2 + 4 HCl → (HO2CCH2)2NCH2CH2N(CH2CO2H)2 + 4 NaCl
This process is used to produce about 80,000 tonnes of EDTA each year.
Impurities cogenerated by this route include glycine and nitrilotriacetic acid; they arise from reactions of the ammonia coproduct.

Biochem/physiol Actions
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) has the ability to block the binding of vasoactive intestinal peptide to macrophage membranes.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is mainly used in the purification of protein, to remove divalent cations and also to prevent protease activity.

Side effects
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) exhibits low acute toxicity with LD50 (rat) of 2.0 g/kg to 2.2 g/kg.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) has been found to be both cytotoxic and weakly genotoxic in laboratory animals. Oral exposures have been noted to cause reproductive and developmental effects.
The same study also found that both dermal exposure to Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) in most cosmetic formulations and inhalation exposure to EDTA in aerosolised cosmetic formulations would produce exposure levels below those seen to be toxic in oral dosing studies.

Veterinary Drugs and Treatments
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a chelating agent that is also used to stop the melting effect of collagenases and proteases on the cornea.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is useful in halting melting through inhibition of matrix metalloproteinases, but is not felt to be useful for melting caused by infectious agents.
As the effect of Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) on metalloproteinases is reversible, it must be administered several times daily to be effective.
ETHYLENEDIAMINTETRAACETIC ACID
1,2-Diaminoethane, 1,2-Ethanediamine; 1,2-Ethylenediamine; 1,2-Diaminoethane; EDA; Ethane-1,2-diamine; Aethaldiamin; Aethylenediamin; 1,2-diaminoaethan; 1,2-Diamino-ethaan; 1, 2-Diamino-Ethano; Dimethylenediamine; Ethyleendiamine; Ethylene-diamine; β-Aminoethylamine CAS NO:107-15-3
Ethylenediamine
1,2-Diaminoethane, 1,2-Ethanediamine; 1,2-Ethylenediamine; 1,2-Diaminoethane; EDA; Ethane-1,2-diamine; Aethaldiamin; Aethylenediamin; 1,2-diaminoaethan; 1,2-Diamino-ethaan; 1, 2-Diamino-Ethano; Dimethylenediamine; Ethyleendiamine; Ethylene-diamine; β-Aminoethylamine CAS NO:107-15-3
ethylenediamine Tetra(methylene phosphonic Acid) Pentasodium Salt
ETHYLENEGLYCOL DIMETHACRYLATE; 2-Methyl-2-Propenoic acid, 1,2-ethanediyl ester; EGDMA; Ethylene Methacrylate; Glycol Dimethacrylate; 1,2-Ethanediol dimethacrylate; Ethylene glycol bis(methacrylate); Methacrylic acid, ethylene ester; 1,2-Bis(Methacryloyloxy)ethane; cas no: 97-90-5
Ethylenediaminetetraacetic Acid Calcium Disodium Salt Hydrate
pentasodium ethylenediamine tetramethylene phosphonate ;pentasodium trihydrogen, ethylenedinitrilotetrakis(methylphosphonate); phosphonic acid, (1,2-ethanediylbis(nitrilobis(methylene)))tetrakis-, pentasodium salt cas no : 7651-99-2
ETHYLENEGLYCOL DIMETHACRYLATE
ETHYLHEXANOL, N° CAS : 104-76-7, Nom INCI : ETHYLHEXANOL, Nom chimique : 2-Ethylhexan-1-ol, N° EINECS/ELINCS : 203-234-3. Ses fonctions (INCI) : Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques. Noms français : 2-ETHYL HEXANOL; 2-ETHYL-1-HEXANOL; 2-Ethylhexyl alcohol; Alcool 2-éthylhexylique; Ethyl -2 hexanol;ETHYL-2 HEXANOL-1 ETHYLHEXANOL; Éthyl-2 hexanol; Noms anglais :2-Ethylhexanol; Utilisation et sources d'émission; Solvant de colorants, solvant de résines
ETHYLHEXANOIC ACID
Ethylhexanoic Acid is a colorless to light yellow liquid with a pungent odor.
Furthermore, Ethylhexanoic Acid is commonly used in the production of various chemicals, including plasticizers and lubricants.
Ethylhexanoic Acid can be harmful if ingested or inhaled, and proper safety precautions should be taken when handling it.


CAS Number: 2396-84-1
EC Number: 205-743-6
Chemical formula: C8H16O2
Molar mass: 144.214 g·mol−1
Appearance: Colorless liquid



APPLICATIONS


Ethylhexanoic Acid is used as a chemical intermediate for many products.
Moreover, Ethylhexanoic Acid is used in alkyd resins.

Ethylhexanoic Acid is used in the mid-1980s as a wood preservative to replace chlorophenols.
Further, Ethylhexanoic Acid is used to make plasticizers, lubricants, detergents, flotation aids, corrosion inhibitors, and alkyd resins.

Ethylhexanoic Acid is also used as a co-solvent and defoamer in pesticides, as the active ingredient in the wood preservative Sinesto B (not used in the US), in paint dryers, heat stabilizers for PVC, and as a catalyst for polyurethane foaming, solvent extraction, and dye granulation.
What is more, Ethylhexanoic Acid is not found in any pesticide products registered in the US.


Industry uses of Ethylhexanoic Acid:

Anti-adhesive agents
Corrosion inhibitor
Corrosion inhibitors and anti-scaling agents
Intermediate
Intermediates
Lubricants and lubricant additives
Lubricating agent
Not Known or Reasonably Ascertainable
Other
Other (specify)
Paint additives and coating additives not described by other categories
Process regulators
Processing aids, not otherwise listed
Propellants and blowing agents
Solvent


Ethylhexanoic Acid is used in the production of plasticizers to improve the flexibility and durability of plastics.
Furthermore, Ethylhexanoic Acid is a building block in the production of coatings, such as resins and polyurethanes.

Ethylhexanoic Acid is used in metalworking fluids to cool and lubricate metalworking machines.
Moreover, Ethylhexanoic Acid is used in the production of lubricants to reduce friction and wear between two surfaces.
Ethylhexanoic Acid is a raw material in the production of pharmaceuticals, such as antibiotics and anti-inflammatory drugs.

Ethylhexanoic Acid is used in the production of various chemical intermediates for further processing.
Besides, Ethylhexanoic Acid is used in the production of heat stabilizers for PVC applications.

Ethylhexanoic Acid is used in the production of fuel additives to improve fuel efficiency and reduce emissions.
In addition, Ethylhexanoic Acid is used as a precursor in the synthesis of various catalysts to speed up chemical reactions.

Ethylhexanoic Acid is used as a solvent in the production of various chemicals and materials.
More to that, Ethylhexanoic Acid is used in the production of agrochemicals, such as herbicides, fungicides, and insecticides, to protect crops from pests and diseases.


Here are some additional applications of Ethylhexanoic Acid:

Paint driers:

Ethylhexanoic Acid is used as a paint drier, which accelerates the drying process of paints and varnishes.

Adhesives:

Ethylhexanoic Acid is used as a raw material in the production of various adhesives, such as pressure-sensitive adhesives and hot-melt adhesives.

Corrosion inhibitors:

Ethylhexanoic Acid is used as a component in the formulation of corrosion inhibitors, which protect metals from corrosion.

Resin additives:

Ethylhexanoic Acid is used as a resin additive in the production of polyester and alkyd resins, which find use in coatings, adhesives, and plastics.

Surfactants:

Ethylhexanoic Acid is used in the production of surfactants, which are used to modify the surface tension of liquids, thereby improving their wetting and spreading properties.

Fragrances:

Ethylhexanoic Acid is used as a fragrance ingredient in the production of perfumes and other scented products.

Textile auxiliaries:

Ethylhexanoic Acid is used in the production of textile auxiliaries, which are used to enhance the performance of textile products, such as dyes, finishes, and coatings.

Metal salts:

Ethylhexanoic Acid is used to produce metal salts, which find use in various applications, such as inks, pigments, and catalysts.

Rubber additives:

Ethylhexanoic Acid is used as a rubber additive in the production of synthetic rubbers, which find use in various products, such as tires, hoses, and seals.

Plasticizers:

Ethylhexanoic Acid is a key component in the production of phthalate-free plasticizers, which are used in the production of food packaging materials and medical devices.

Coatings:

Ethylhexanoic Acid is used as a reactant in the production of acrylic resins, which find use in the production of paints, coatings, and adhesives.

Metalworking fluids:

Ethylhexanoic Acid is a common component in metalworking fluids due to its excellent lubricity and cooling properties.

Lubricants:

Ethylhexanoic Acid is used as a metal deactivator in lubricants to prevent oxidation and improve their performance at high temperatures.

Pharmaceuticals:

Ethylhexanoic Acid is used as a chiral building block in the synthesis of various drugs, such as the anti-inflammatory drug Naproxen.

Chemical intermediates:

Ethylhexanoic Acid is used as a key intermediate in the synthesis of various chemicals, such as fragrances, flavors, and surfactants.

Heat stabilizers:

Ethylhexanoic Acid is used in the production of heat stabilizers for PVC applications to prevent degradation and extend the lifespan of the material.

Fuel additives:

Ethylhexanoic Acid is used as a component in the production of fuel additives, such as octane boosters, which improve the performance and efficiency of gasoline engines.

Catalysts:

Ethylhexanoic Acid is used as a precursor in the synthesis of various catalysts, such as tin and zinc carboxylates, which find use in various chemical reactions.

Solvents:

Ethylhexanoic Acid is used as a solvent in the production of various chemicals, such as resins, coatings, and adhesives.

Agrochemicals:

Ethylhexanoic Acid is used as a key component in the production of herbicides, fungicides, and insecticides to protect crops from pests and diseases.


Overall, Ethylhexanoic Acid is a versatile chemical that finds use in various applications across different industries, thanks to its unique properties and versatility.


Ethylhexanoic Acid is not commonly used in consumer products, as it is primarily an industrial chemical with a wide range of industrial applications.
However, Ethylhexanoic Acid may be used as a raw material in the production of certain consumer products, such as coatings, adhesives, and plastics.

Additionally, some niche applications, such as the use of Ethylhexanoic Acid as a component in certain fragrances, may have consumer uses.
Overall, the use of Ethylhexanoic Acid is more common in industrial and commercial settings rather than in consumer products.


Ethylhexanoic Acid has various industrial applications, such as:

Coolant in automotives
Synthetic lubricant
Wetting agent
Co-solvent
Drying of paints
Defoaming agent in pesticides


Ethylhexanoic Acid is used as a synthetic lubricant due to its ability to reduce friction and wear between moving parts.
Further to that, Ethylhexanoic Acid is commonly used as a drying agent in paints and coatings to accelerate the drying process and improve film formation.

As a coolant in automotive applications, Ethylhexanoic Acid helps dissipate heat and prevent engine damage from overheating.
Ethylhexanoic Acid is utilized as a defoaming agent in pesticides to reduce foam formation during application and improve effectiveness.

In metalworking, Ethylhexanoic Acid is used as a corrosion inhibitor to protect against rust and other forms of corrosion.
Ethylhexanoic Acid is used as a wetting agent to reduce the surface tension of liquids and improve their ability to spread and penetrate surfaces.



DESCRIPTION


Ethylhexanoic acid is the organic compound with the formula CH3(CH2)3CH(C2H5)CO2H.
Furthermore, Ethylhexanoic acid is a carboxylic acid that is widely used to prepare lipophilic metal derivatives that are soluble in nonpolar organic solvents.

Ethylhexanoic acid is a colorless viscous oil.
More to that, Ethylhexanoic acid is supplied as a racemic mixture.
2-Ethylhexanoic acid is a branched-chain fatty acid.

Ethylhexanoic Acid is a colorless liquid with a pungent odor.
Thus, Ethylhexanoic Acid is soluble in alcohol, acetone, and ether.

Ethylhexanoic Acid is a carboxylic acid with the chemical formula C8H16O2.
Moreover, Ethylhexanoic Acid is a colorless liquid with a rancid odor and is soluble in water, ethanol, and ether.
It is also known as 2-ethylhexanoic acid or 2-EHA.

Ethylhexanoic Acid is primarily used as a raw material for the production of various chemicals and materials such as synthetic lubricants, plasticizers, and coatings.
Further, Ethylhexanoic Acid also has applications in the pharmaceutical and food industries.

Ethylhexanoic acid is a natural product found in Vitis vinifera and Artemisia arborescens with data available.
What is more, Ethylhexanoic Acid is a colorless liquid with a pungent odor.
Ethylhexanoic Acid is a carboxylic acid that belongs to the family of fatty acids.

Ethylhexanoic Acid is soluble in water, alcohol, and ether.
Further to that, Ethylhexanoic Acid has a wide range of industrial applications.

Ethylhexanoic Acid is used as a synthetic lubricant and as a drying agent in paints.
In addition, Ethylhexanoic Acid is also used as a coolant in automotive applications and as a defoaming agent in pesticides.

Ethylhexanoic Acid is produced through the oxidation of octanol or via the hydroformylation of butadiene.
Moreover, Ethylhexanoic Acid is also found naturally in human sweat and in breast milk.



PROPERTIES


Molecular Weight: 144.21
XLogP3: 2.6
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 5
Exact Mass: 144.115029749
Monoisotopic Mass: 144.115029749
Topological Polar Surface Area: 37.3 Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 99.4
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Boiling point: 226 - 229 °C (1013 hPa)
Density: 0.91 g/cm3 (20 °C)
Explosion limit: 0.9 - 6.7 %(V)
Flash point: 114 °C
Ignition temperature: 310 °C
Melting Point: -59 °C
pH value: 3 (1.4 g/l, H₂O, 20 °C)
Vapor pressure: Solubility: 1.4 g/l



FIRST AID


Skin Contact:

If Ethylhexanoic Acid comes into contact with skin, immediately remove any contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes.
Seek medical attention if skin irritation, redness, or pain persists.


Eye Contact:

If Ethylhexanoic Acid comes into contact with eyes, flush the affected eye with water for at least 15 minutes, lifting the upper and lower eyelids occasionally.
Seek medical attention immediately.


Inhalation:

If Ethylhexanoic Acid is inhaled, remove the affected person to fresh air immediately.
If the person is not breathing, administer artificial respiration.
Seek medical attention if the person experiences difficulty breathing, coughing, or wheezing.


Ingestion:

If Ethylhexanoic Acid is ingested, do not induce vomiting.
Rinse the mouth with water and drink plenty of water to dilute the acid.
Seek medical attention immediately.


Personal Protective Equipment:

Always wear personal protective equipment when handling Ethylhexanoic Acid, including gloves, goggles, and a lab coat or protective clothing.


Spill Response:

In the event of a spill, isolate the area and keep unauthorized personnel away.
Wear personal protective equipment and contain the spill with an absorbent material.
Collect the contaminated material and dispose of it according to local regulations.


It is important to note that Ethylhexanoic Acid can cause severe skin and eye irritation, and may be harmful if inhaled or ingested.
Seek immediate medical attention if exposure occurs.



HANDLING AND STORAGE


Ethylhexanoic Acid should be stored in a cool, dry, well-ventilated area, away from direct sunlight and sources of heat or ignition.
Further, Ethylhexanoic Acid should be kept in a tightly sealed container and handled only in a fume hood or with appropriate personal protective equipment.
Ethylhexanoic Acid should be stored separately from incompatible materials such as strong oxidizers, acids, and bases.

Containers of Ethylhexanoic Acid should be labeled with the appropriate hazard warnings and handling instructions.
When handling Ethylhexanoic Acid, appropriate personal protective equipment should be worn, including gloves, safety goggles, and a lab coat or apron.

In case of skin or eye contact, immediately flush the affected area with plenty of water for at least 15 minutes and seek medical attention.
If Ethylhexanoic Acid is ingested, do not induce vomiting and seek medical attention immediately.

Spills of Ethylhexanoic Acid should be cleaned up immediately using absorbent materials and appropriate protective equipment.
Disposal of Ethylhexanoic Acid should be done in accordance with local, state, and federal regulations, and should not be disposed of in regular trash or down the drain.

Ethylhexanoic Acid should be kept away from children and unauthorized personnel, and should only be handled by trained professionals who are familiar with the hazards and proper handling procedures.



SYNONYMS


2-ETHYLHEXANOIC ACID
149-57-5
2-Ethylcaproic acid
Hexanoic acid, 2-ethyl-
Ethylhexanoic acid
Ethylhexoic acid
2-Ethylhexoic acid
Butylethylacetic acid
2-Butylbutanoic acid
3-Heptanecarboxylic acid
Ethyl hexanoic acid
2-ethyl-hexoic acid
2-ethyl hexanoic acid
alpha-Ethylcaproic acid
2-ethyl-hexanoic acid
Ethyl hexanoic acid, 2-
2 ETHYL HEXANOIC ACID
alpha-ethyl caproic acid
.alpha.-Ethylcaproic acid
2-Ethyl-1-hexanoic acid
(+/-)-2-ETHYLHEXANOIC ACID
01MU2J7VVZ
2-ETHYL HEXOIC ACID,AR
61788-37-2
CHEBI:89058
NSC-8881
2-ethylhexanoicacid
2-Ethylhexansaeure
2-Ethylhexanoic acid, >=99%
2-Ethylhexanoic acid, analytical standard
CAS-149-57-5
CCRIS 3348
HSDB 5649
Kyselina 2-ethylkapronova [Czech]
NSC 8881
Kyselina 2-ethylkapronova
EINECS 205-743-6
UNII-01MU2J7VVZ
Kyselina heptan-3-karboxylova [Czech]
BRN 1750468
Kyselina heptan-3-karboxylova
AI3-01371
Hexanoic acid, 2-ethyl-, (-)-
EINECS 262-971-9
MFCD00002675
2-Ethylcapronic acid
2-Ethyl-Hexonic acid
alpha-Ethylhexanoic acid
.alpha.-Ethylhexanoic acid
EC 205-743-6
SCHEMBL25800
2-Ethylhexanoic acid, 99%
MLS002415695
CHEMBL1162485
DTXSID9025293
WLN: QVY4 & 2
NSC8881
HMS2267F21
STR05759
2-ETHYLHEXANOIC ACID [HSDB]
Tox21_201406
Tox21_300108
LMFA01020087
AKOS009031416
AT29893
CS-W016381
SB44987
SB44994
Hexanoic acid,2-ethyl-, tridecyl ester
NCGC00091324-01
NCGC00091324-02
NCGC00091324-03
NCGC00253985-01
NCGC00258957-01
SMR001252268
E0120
2-Ethylhexanoic Acid
2-Ethylcaproic Acid
Isooctanoic Acid
Octanoic Acid, 2-ethyl-
2-ethylhexoic acid
Ethylhexoic Acid
FT-0612273
FT-0654390
EN300-20410
Q209384
W-109079
F0001-0703
Z104478072
18FEB650-7573-4EA0-B0CD-9D8BED766547
2-Ethylhexanoic acid, Pharmaceutical Secondary Standard; Certified Reference Material
ETHYLHEXANOL ( Alcool 2-éthylhexylique)
ETHYLHEXYL ACRYLATE, N° CAS : 103-11-7, Nom INCI : ETHYLHEXYL ACRYLATE. N° EINECS/ELINCS : 203-080-7. Ses fonctions (INCI) : Agent fixant : Permet la cohésion de différents ingrédients cosmétiques. Noms français : 2-ETHYLHEXYL-2-PROPENOATE 2-PROPENOIC ACID, 2-ETHYLHEXYL ESTER Acrylate d'éthyl-2 hexyle PROPENOATE-2 D'ETHYL-2 HEXYLE Noms anglais : 2-Ethylhexyl acrylate ACRYLIC ACID 2-ETHYLHEXYL ESTER ACRYLIC ACID, 2-ETHYLHEXYL ESTER ETHYLHEXYL-2 ACRYLATE Utilisation et sources d'émission Fabrication de polymères
ETHYLHEXYL ACRYLATE ( Acrylate d'éthyl-2 hexyle)
ETHYLHEXYL BENZOATE, N° CAS : 5444-75-7. Nom INCI : ETHYLHEXYL BENZOATE. Nom chimique : 2-Ethylhexyl benzoate. N° EINECS/ELINCS : 226-641-8. Ses fonctions (INCI): Emollient : Adoucit et assouplit la peau. Agent d'entretien de la peau : Maintient la peau en bon état. Solvant : Dissout d'autres substances. 226-641-8 [EINECS] 2-Ethylhexyl benzoate 2-Ethylhexyl-benzoat [German] 4Y2&1OVR [WLN] 5444-75-7 [RN] Benzoate de 2-éthylhexyle [French] Benzoic acid, 2-ethylhexyl ester [ACD/Index Name] MFCD00072620 [MDL number] [5444-75-7] 2-Ethylhexylbenzoate benzoic acid 2-ethyl-hexyl ester BENZOICACID2-ETHYLHEXYLESTER Ethylhexyl benzoate PI-46931 Velate 368
Ethylhexyl benzoate ( Benzoate de 2-éthylhexyle)
ETHYLHEXYL COCOATE, N° CAS : 92044-87-6. Nom INCI : ETHYLHEXYL COCOATE. N° EINECS/ELINCS : 295-366-3. Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau
ETHYLHEXYL COCOATE
ETHYLHEXYL DIMETHYL PABA. N° CAS : 21245-02-3. Nom INCI : ETHYLHEXYL DIMETHYL PABA, Nom chimique : 2-Ethylhexyl 4-(dimethylamino)benzoate. N° EINECS/ELINCS : 244-289-3, Classification : Filtre UV Chimique, Règlementé. La concentration maximale autorisée en cosmétique est la suivante : 8 %.. Ses fonctions (INCI) : Absorbant UV : Protège le produit cosmétique contre les effets de la lumière UV. Filtre UV : Permet de filtrer certains rayons UV afin de protéger la peau ou les cheveux des effets nocifs de ces rayons.Noms français : OCTYL DIMETHYL PABA Noms anglais : 2-ETHYLHEXYL P-DIMETHYLAMINOBENZOATE; BENZOIC ACID, 4-(DIMETHYLAMINO)-, 2-ETHYLHEXYL ESTER
ETHYLHEXYL COCOATE


Ethylhexyl Cocoate, also known as Octyl Cocoate, is an ester compound formed by the reaction of ethylhexanol (2-ethylhexanol) with fatty acids derived from coconut oil.
Ethylhexyl Cocoate is commonly used in cosmetics, personal care products, and industrial applications as an emollient, moisturizer, and texturizer due to its lightweight and non-greasy properties.
Ethylhexyl Cocoate is valued for its ability to improve the spreadability of formulations, provide a smooth skin feel, and contribute to a luxurious sensory experience.

CAS Number: 65381-09-1
EC Number: 265-499-7



APPLICATIONS


Ethylhexyl Cocoate is extensively used in cosmetic and personal care products for its versatile properties.
Ethylhexyl Cocoate finds application in body lotions, contributing to their lightweight texture and moisturizing effects.

In facial moisturizers, Ethylhexyl Cocoate helps maintain the skin's hydration without a greasy residue.
Ethylhexyl Cocoate is a common ingredient in sunscreens, aiding in the dispersion of UV filters and enhancing product efficacy.
Ethylhexyl Cocoate improves the spreadability of makeup products, ensuring smooth and even application.
Ethylhexyl Cocoate is utilized in lip balms, providing a non-sticky texture and offering moisturizing benefits.

Ethylhexyl Cocoate contributes to hair care products such as conditioners, enhancing hair shine and manageability.
Ethylhexyl Cocoate is included in shower gels and body washes to provide a silky and luxurious feel on the skin.

Ethylhexyl Cocoate is employed in after-shave lotions and balms to soothe the skin while adding a non-greasy finish.
Ethylhexyl Cocoate plays a role in foundation formulations, helping to create a seamless and natural-looking complexion.
Ethylhexyl Cocoate is used in baby care products, ensuring gentle hydration and comfort for delicate skin.
Ethylhexyl Cocoate contributes to serums, aiding the even distribution of active ingredients for targeted skincare benefits.
In hand creams, Ethylhexyl Cocoate prevents dryness and promotes soft, supple hands.

Ethylhexyl Cocoate is found in anti-aging products, contributing to improved skin texture and moisture retention.
Ethylhexyl Cocoate enhances the solubility of lipophilic actives in skincare formulations.
Ethylhexyl Cocoate is incorporated in body oils, providing a luxurious, non-greasy feel while deeply moisturizing the skin.

Ethylhexyl Cocoate plays a role in BB creams and tinted moisturizers, offering both coverage and hydration.
Ethylhexyl Cocoate contributes to massage oils, allowing for a smooth glide and comfortable application.
Ethylhexyl Cocoate is used in natural and organic product formulations, appealing to consumers seeking clean beauty options.
Ethylhexyl Cocoate finds application in post-workout skincare, soothing the skin after physical activity.

Ethylhexyl Cocoate is utilized in pre-tanning oils, preparing the skin for sun exposure while maintaining hydration.
Ethylhexyl Cocoate enhances the stability of formulations, helping prevent ingredient separation and prolonging shelf life.

Ethylhexyl Cocoate is employed in therapeutic creams and ointments due to its non-irritating and moisturizing properties.
Ethylhexyl Cocoate aligns with the formulation of matte-finish and oil-free cosmetics for a non-greasy look.
Ethylhexyl Cocoate is recognized for its ability to create a protective barrier on the skin, making it a valuable ingredient in various skincare and cosmetic products.
Ethylhexyl Cocoate is an essential ingredient in body butters and creams, contributing to their rich and moisturizing texture.
Ethylhexyl Cocoate finds use in facial cleansing oils, effectively removing makeup and impurities while leaving the skin soft.

Ethylhexyl Cocoate is added to primer formulations, creating a smooth canvas for makeup application.
Ethylhexyl Cocoate is incorporated into lip glosses and lipsticks, providing a comfortable and hydrating feel on the lips.
Ethylhexyl Cocoate is used in cosmetic products with anti-inflammatory properties, assisting in calming and soothing the skin.
Ethylhexyl Cocoate is employed in cuticle oils, softening and nourishing the cuticles for healthier nails.

Ethylhexyl Cocoate is included in hair styling products like serums and sprays, reducing frizz and adding shine.
Ethylhexyl Cocoate is utilized in body scrubs, enhancing their application and promoting soft and rejuvenated skin.
Ethylhexyl Cocoate contributes to foot creams, aiding in the prevention of dry and cracked heels.
Ethylhexyl Cocoate is found in men's grooming products, offering moisturization and a comfortable shave.

Ethylhexyl Cocoate is used in makeup removers, efficiently dissolving makeup without leaving an oily residue.
Ethylhexyl Cocoate is added to body mists, providing a refreshing and non-sticky sensation on the skin.
Ethylhexyl Cocoate is utilized in under-eye creams, helping to minimize dryness and fine lines.
Ethylhexyl Cocoate is employed in body powders, enhancing their texture and providing a silky application.
Ethylhexyl Cocoate contributes to hair conditioners, improving manageability and promoting a healthy appearance.

Ethylhexyl Cocoate is found in natural deodorants, helping to maintain skin comfort throughout the day.
Ethylhexyl Cocoate is used in cooling and soothing gels for after-sun care, offering relief to sun-exposed skin.
Ethylhexyl Cocoate is added to massage creams, ensuring a smooth and enjoyable massage experience.
Ethylhexyl Cocoate is utilized in self-tanning products, aiding in even color application and prolonging tan appearance.

Ethylhexyl Cocoate is included in post-procedure skincare, providing gentle hydration and aiding in skin recovery.
Ethylhexyl Cocoate contributes to body lotions with aromatic blends, offering a pleasant scent along with moisturization.
Ethylhexyl Cocoate is used in cosmetic products targeted at sensitive or reactive skin, providing a soothing touch.

Ethylhexyl Cocoate is employed in hand sanitizers, preventing skin dryness caused by frequent use.
Ethylhexyl Cocoate is added to body creams with a quick-absorbing formula, leaving no sticky residue.
Ethylhexyl Cocoate's role in formulations extends to luxury skincare, enhancing the overall sensorial experience of high-end products.

Ethylhexyl Cocoate is a key ingredient in tinted moisturizers, providing hydration and a hint of color for a natural look.
Ethylhexyl Cocoate is used in post-shave products, soothing and moisturizing the skin after shaving.
Ethylhexyl Cocoate is added to body creams with fast-absorbing properties, allowing for quick dressing after application.
Ethylhexyl Cocoate finds use in shaving creams, aiding in the smooth gliding of razors and minimizing irritation.

Ethylhexyl Cocoate contributes to hand lotions, maintaining softness and comfort even with frequent hand washing.
Ethylhexyl Cocoate is employed in anti-itch creams, providing relief to irritated and sensitive skin.
Ethylhexyl Cocoate is utilized in facial masks, helping to improve the spreadability and adherence of mask formulations.

Ethylhexyl Cocoate is included in facial mists, offering a burst of hydration and refreshment throughout the day.
Ethylhexyl Cocoate finds application in cooling gels for sore muscles, providing comfort and relaxation.
Ethylhexyl Cocoate is added to body oils, enhancing their ability to deeply moisturize and nourish the skin.

Ethylhexyl Cocoate is used in men's grooming products such as beard oils, promoting a well-groomed appearance.
Ethylhexyl Cocoate contributes to lip balms with SPF protection, combining hydration and sun protection.
Ethylhexyl Cocoate is utilized in dry shampoo formulations, aiding in the absorption of excess oils.
Ethylhexyl Cocoate is included in body firming creams, contributing to smoother and more toned skin.

Ethylhexyl Cocoate finds use in foot scrubs, enhancing their exfoliating and rejuvenating effects.
Ethylhexyl Cocoate is added to bath oils, providing a luxurious and moisturizing bathing experience.
Ethylhexyl Cocoate is employed in natural deodorant sticks, ensuring comfortable and effective odor protection.
Ethylhexyl Cocoate contributes to body washes with creamy textures, leaving the skin feeling soft and nourished.

Ethylhexyl Cocoate is used in pre-makeup primers, creating a smooth and hydrated canvas for makeup application.
Ethylhexyl Cocoate is included in body serums, offering concentrated hydration and nutrients to the skin.
Ethylhexyl Cocoate finds application in cuticle creams, promoting healthy and conditioned cuticles.
Ethylhexyl Cocoate is utilized in cosmetic products with soothing effects on irritated skin, such as post-exfoliation treatments.

Ethylhexyl Cocoate is added to body balms, providing intensive hydration and protection for dry skin areas.
Ethylhexyl Cocoate contributes to makeup setting sprays, helping to lock in makeup while providing a refreshing mist.
Ethylhexyl Cocoate is found in multi-purpose products like all-in-one creams, offering a range of benefits in a single formulation.

Ethylhexyl Cocoate is incorporated into body lotions for its ability to create a lightweight, non-greasy formula that leaves the skin soft and smooth.
Ethylhexyl Cocoate finds use in facial serums, helping to improve the skin's texture and providing a youthful appearance.

Ethylhexyl Cocoate is added to hand creams, protecting the skin from dryness and environmental stressors.
Ethylhexyl Cocoate is utilized in body washes and shower gels, contributing to their creamy lather and moisturizing properties.
Ethylhexyl Cocoate is included in facial cleansers, aiding in the gentle removal of impurities without stripping the skin's natural oils.
Ethylhexyl Cocoate is employed in lip care products, such as lip scrubs, offering exfoliation and hydration.

Ethylhexyl Cocoate finds application in soothing creams for skin conditions like eczema, providing relief and comfort.
Ethylhexyl Cocoate contributes to massage oils, enhancing the glide and promoting relaxation during massages.
Ethylhexyl Cocoate is added to foot scrubs, revitalizing tired feet and helping to remove dead skin cells.
Ethylhexyl Cocoate is utilized in beard balms, taming and nourishing facial hair for a well-groomed appearance.

Ethylhexyl Cocoate is found in makeup remover wipes, effectively dissolving makeup and impurities while maintaining skin hydration.
Ethylhexyl Cocoate is employed in bath bombs, infusing the water with moisturizing and skin-soothing properties.

Ethylhexyl Cocoate contributes to natural sunscreens, aiding in the dispersion of mineral sunscreens and providing hydration.
Ethylhexyl Cocoate is included in hair masks, adding moisture and shine to dry or damaged hair.
Ethylhexyl Cocoate is added to foundation formulations, enhancing the blendability and natural finish of the product.

Ethylhexyl Cocoate is utilized in lip care products like lip masks, providing deep hydration and softness.
Ethylhexyl Cocoate is employed in cuticle balms, promoting healthy nails and cuticles.
Ethylhexyl Cocoate finds use in makeup setting powders, preventing cakiness and maintaining a fresh makeup look.

Ethylhexyl Cocoate is added to body exfoliators, helping to polish the skin's surface and leave it feeling renewed.
Ethylhexyl Cocoate is found in soothing aftersun gels, providing relief to sunburned or irritated skin.

Ethylhexyl Cocoate is utilized in priming sprays, creating a hydrated and even canvas for makeup application.
Ethylhexyl Cocoate is included in hair serums, taming frizz and adding a healthy shine to the hair.

Ethylhexyl Cocoate is employed in foot creams, aiding in the prevention of dry, cracked heels.
Ethylhexyl Cocoate contributes to makeup cushion compacts, offering foundation with added skincare benefits.
Ethylhexyl Cocoate finds application in fragrance-free skincare products, appealing to individuals with sensitive skin or fragrance allergies.



DESCRIPTION


Ethylhexyl Cocoate, also known as Octyl Cocoate, is an ester compound formed by the reaction of ethylhexanol (2-ethylhexanol) with fatty acids derived from coconut oil.
Ethylhexyl Cocoate is commonly used in cosmetics, personal care products, and industrial applications as an emollient, moisturizer, and texturizer due to its lightweight and non-greasy properties.
Ethylhexyl Cocoate is valued for its ability to improve the spreadability of formulations, provide a smooth skin feel, and contribute to a luxurious sensory experience.

In cosmetics and skincare, Ethylhexyl Cocoate is often incorporated into various products such as lotions, creams, sunscreens, makeup products, and hair care items.
Its versatile properties make it suitable for formulations targeting different skin types and preferences.
As an emollient, Ethylhexyl Cocoate helps to lock in moisture, leaving the skin soft and hydrated.
Its non-comedogenic nature makes it suitable for facial products as well.

Ethylhexyl Cocoate is a versatile and widely used ester compound derived from the reaction of ethylhexanol and coconut oil fatty acids.
Ethylhexyl Cocoate is valued for its ability to enhance the sensory experience of cosmetic and personal care products.

With a clear to slightly yellowish appearance, Ethylhexyl Cocoate boasts a lightweight texture that is non-greasy on the skin.
Known for its emollient properties, it effectively locks in moisture, leaving the skin feeling soft and hydrated.
Ethylhexyl Cocoate is often selected for formulations targeting various skin types due to its compatibility with sensitive and acne-prone skin.

Ethylhexyl Cocoate finds its place in lotions, creams, sunscreens, and makeup products, contributing to their smooth application and skin-feel.
As a texture enhancer, Ethylhexyl Cocoate aids in the even spreadability of products, enhancing the overall application experience.
The chemical aligns with clean beauty principles and natural formulations, fitting well into environmentally conscious cosmetic products.

Ethylhexyl Cocoate is known for its biodegradability and relatively low toxicity, making it an eco-friendly choice.
Ethylhexyl Cocoate is particularly useful in formulations where a non-comedogenic ingredient is desirable, making it suitable for facial skincare products.
Its ability to create a protective barrier on the skin contributes to its inclusion in moisturizers and creams.

Ethylhexyl Cocoate's compatibility with a wide range of other ingredients allows for versatile formulations across the cosmetics industry.
In sunscreens, Ethylhexyl Cocoate helps to disperse UV filters evenly, improving the product's overall efficacy.
Ethylhexyl Cocoate plays a role in maintaining hair health by adding shine and smoothness to hair care formulations.

Ethylhexyl Cocoate's non-greasy texture makes it a preferred choice for oil-free or matte-finish cosmetic products.
Ethylhexyl Cocoate has the capacity to enhance the solubility of lipophilic (fat-soluble) active ingredients in formulations.
Ethylhexyl Cocoate is recognized for its role in providing a luxurious sensory experience, making products more enjoyable to use.
Its versatility extends to industrial applications, where it is used in lubricants and metalworking fluids for its lubricating properties.

Ethylhexyl Cocoate contributes to the stability of formulations, helping to prevent the separation of ingredients.
Ethylhexyl Cocoate aligns with the trend towards multifunctional products, as Ethylhexyl Cocoate can simultaneously moisturize and improve texture.
Ethylhexyl Cocoate is included in some pharmaceutical formulations and therapeutic creams due to its gentle and hydrating nature.

Ethylhexyl Cocoate's mild and pleasant odor makes it suitable for products with added fragrances or scents.
Its compatibility with various skin types extends its use to baby care products and products for sensitive skin.
Ethylhexyl Cocoate is preferred in natural and organic product formulations, appealing to consumers seeking cleaner ingredients.
Ethylhexyl Cocoate's non-sensitizing properties, along with its moisturizing benefits, make it a valuable ingredient in modern cosmetics.



PROPERTIES


Chemical Formula: C26H50O3
Molecular Weight: Approximately 410.68 g/mol
Appearance: Clear to slightly yellowish liquid
Odor: Characteristic odor
Texture: Lightweight and non-greasy
Solubility: Soluble in oils and organic solvents
Melting Point: Approximately -4°C to -3°C (25°F to 27°F)
Boiling Point: Varies with composition, typically around 200°C (392°F)
Flash Point: Varies with composition, typically above 100°C (212°F)
Density: Approximately 0.9 - 0.95 g/cm³
Viscosity: Low to moderate viscosity depending on formulation and temperature
pH: Neutral to slightly acidic
Compatibility: Compatible with a wide range of cosmetic ingredients



FIRST AID


Inhalation:
If inhaled, move the person to fresh air.
If breathing is difficult, provide oxygen and seek medical attention.

Skin Contact:
In case of skin contact, immediately remove contaminated clothing and wash the affected area with plenty of soap and water.
If irritation persists, seek medical attention.
Wash contaminated clothing before reusing.

Eye Contact:
If Ethylhexyl Cocoate comes into contact with the eyes, immediately rinse them gently with water for several minutes, keeping eyelids open.
Remove contact lenses if present and easy to do so.
Seek medical attention if irritation or discomfort persists.

Ingestion:
If accidentally swallowed, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth with water and seek medical attention.
Do not give anything by mouth to an unconscious person.



HANDLING AND STORAGE


Handling:

Ventilation:
Ensure proper ventilation in the work area to prevent the accumulation of vapors or fumes.

Personal Protective Equipment (PPE):
Wear appropriate protective clothing, including gloves and safety goggles, when handling Ethylhexyl Cocoate to prevent skin and eye contact.

Avoid Contact:
Avoid direct contact with skin, eyes, and clothing.
In case of accidental contact, follow the recommended first aid measures and wash affected areas thoroughly with water and soap.

No Smoking:
Do not smoke, eat, or drink while handling the substance to prevent accidental ingestion.

Storage:
Store Ethylhexyl Cocoate away from incompatible materials, such as strong oxidizing agents, acids, and bases.

Spill Control:
Have spill containment measures in place to prevent leaks and spills from spreading. Use absorbent materials to clean up small spills.

Static Electricity:
Ground containers during transfer to prevent the buildup of static electricity, which could result in sparks.


Storage:

Location:
Store Ethylhexyl Cocoate in a cool, dry, well-ventilated area, away from direct sunlight and heat sources.

Temperature:
Maintain storage temperatures within the recommended range to prevent degradation or changes in physical properties.

Containers:
Keep the substance in tightly closed containers made of suitable materials to prevent leakage and contamination.

Compatibility:
Store Ethylhexyl Cocoate away from incompatible materials, such as strong acids, strong bases, and strong oxidizers.

Labeling:
Ensure containers are properly labeled with the substance's name, hazards, and handling instructions.

Segregation:
Store Ethylhexyl Cocoate away from food, beverages, and medical supplies to prevent accidental ingestion.

Fire Safety:
Store away from open flames, sparks, and ignition sources, as the substance may have a flash point above 100°C (212°F).



SYNONYMS


Coco-Caprylate/Caprate
Ethylhexyl Ester of Coconut Fatty Acid
Ethylhexyl Ester of Coco Fatty Acid
Ethylhexyl Coconutate
Ethylhexyl Cocoglyceride
Ethylhexyl Cocoate Ester
Coconut Oil Ethyl Ester
Coco Fatty Acid Ethyl Ester
Ethylhexyl Coconut Oil Ester
Octyl Cocoate
Coconut Acid Ethyl Ester
Coco Alkyl Ester
Ethylhexyl Esters of Coconut Oil
Ester of Coconut Oil Fatty Acid and 2-Ethylhexanol
Ethylhexyl Cocoate Ester
Ester of Coco Fatty Acid and Ethylhexanol
Ethylhexyl Coco Fatty Acid Ester
Coco Fatty Acid Octyl Ester
Ethylhexyl Ester of Coconut Fatty Acid
Ester of Coconut Acid and Ethylhexyl Alcohol
Ethylhexyl Cocoglycinate
Ethylhexyl Ester of Coco Acid
Coconut Fatty Acid Octyl Ester
Octyl Ester of Coco Fatty Acid
Ethylhexyl Coconutate
Coco Ester Ethylhexyl
Ethylhexyl Coconut Fatty Acid Ester
Octyl Ester of Coconut Acid
Ethylhexyl Ester of Coco Fatty Acid
Coco Acid Ethyl Ester
Ethylhexyl Ester of Coconut Acid
Coco Fatty Acid Ethylhexyl Ester
Ethylhexyl Cocoate Ester
Ester of Ethylhexyl Alcohol and Coconut Fatty Acid
Ethylhexyl Coconut Oil Ester
Ethylhexyl Ester of Coco Acid
Coco Acid Octyl Ester
Ethylhexyl Ester of Coconut Oil Fatty Acid
Ethylhexyl Cocoglycolate
Ethylhexyl Cocoate Ethyl Ester
Octyl Ester of Coco Fatty Acid
Ethylhexyl Esters of Coconut Acid
Coco Acid Ethylhexyl Esters
Ethylhexyl Ester of Coconut Acid
Ethylhexyl Coco Fatty Acid Octyl Ester
Ester of Ethylhexanol and Coconut Fatty Acid
Ethylhexyl Cocoate Ethylhexyl Ester
Ethylhexyl Ester of Coco Oil Fatty Acid
Ethylhexyl Cocoate Ethylhexyl Ester
Ester of Ethylhexanol and Coco Acid
Ethylhexyl Ester of Cocos Nucifera Oil Acid
Octyl Ester of Coconut Fatty Acid
Ethylhexyl Ester of Coco Acid and 2-Ethylhexanol
Ethylhexyl Coconutate Ester
Ethylhexyl Ester of Cocos Nucifera Acid
Ethylhexyl Coco Fatty Acid Ethyl Ester
Octyl Coconut Acid Ester
Ethylhexyl Ester of Cocos Nucifera Oil Fatty Acid
Ethylhexyl Cocoglycerides
Ethylhexyl Coconut Acid Ester
Octyl Esters of Coco Fatty Acid
Ethylhexyl Ester of Coconut Acid and Octyl Alcohol
Ethylhexyl Ester of Cocos Nucifera Acid
Ethylhexyl Coco Fatty Acid Cocoate
Ethylhexyl Ester of Cocos Nucifera Oil Fatty Acid
Ethylhexyl Cocoate of Coconut Acid
Octyl Cocoate of Coco Acid
Ethylhexyl Ester of Coconut Fatty Acid and Octyl Alcohol
Ethylhexyl Coco Fatty Acid Coconutate
Ethylhexyl Ester of Cocos Nucifera Oil Acid
Ethylhexyl Cocoate of Cocos Nucifera Acid
Octyl Ester of Cocos Nucifera Oil Acid
Ethylhexyl Ester of Cocos Nucifera Oil Fatty Acid
Octyl Ester of Cocos Nucifera Acid
Ethylhexyl Cocoate of Coconut Oil Fatty Acid
ETHYLHEXYL DIMETHYL PABA
ETHYLHEXYL DIMETHYL PABA Ethylhexyl Dimethyl PABA(Escalol 507). Escalol 507 UV filter by Ashland Specialty Chemical acts as a UV filter. It is a powerful oil-soluble UV-B absorber and offers protection against UV-B and UV-A radiation. It provides cost-effective performance and excellent safety profile. Escalol 507 UV filter finds application in formulating sun-care (after-sun, self-tanning and sunscreen application), body- & facial-care formulas and color cosmetics. Abstract Ethylhexyl Dimethyl PABA(Escalol 507)-aminobenzoic acid (PABA) is an oily yellow liquid derivative of water-soluble PABA commonly used in sunscreen. Ethylhexyl Dimethyl PABA(Escalol 507) is widely used as an ingredient in many cosmetics at an average concentration of 1.25% (0.5-2.0%) in Korea. Previous studies, including those involving animals, have demonstrated that Ethylhexyl Dimethyl PABA(Escalol 507) is toxic to the following four organs: testis, epididymis, spleen, and liver. In addition, experiments using human keratinocytes found that Ethylhexyl Dimethyl PABA(Escalol 507) inhibits cell growth and DNA synthesis at low concentrations, and halted the cell cycle of MM96L cells (human melanoma cell line) at the G1 phase. Despite limited clinical data in humans, many studies have confirmed increased mutagenicity of Ethylhexyl Dimethyl PABA(Escalol 507) following exposure to sunlight, which suggests that this molecule is likely to contribute to onset of sun-induced cancer despite protecting the skin through absorption of UVB. For risk assessment, the no observed adverse effect level (NOAEL) chosen was 100 mg/kg bw/day in a 4 weeks oral toxicity study. Systemic exposure dosage (SED) was 0.588 mg/kg bw/day for maximum use of Ethylhexyl Dimethyl PABA(Escalol 507) in cosmetics. Based on the risk assessment and exposure scenarios conducted in this study, the margin of safety (MOS) was calculated to be 180.18 for a sunscreen containing 8% Ethylhexyl Dimethyl PABA(Escalol 507), which is the maximum level allowed by the relevant domestic authorities. Ethylhexyl Dimethyl PABA(Escalol 507)-aminobenzoic acid (PABA) is an oily yellow liquid derivative of water-soluble PABA commonly used in sunscreen. Ethylhexyl Dimethyl PABA(Escalol 507) is widely used as an ingredient in many cosmetics at an average concentration of 1.25% (0.5-2.0%) in Korea. Previous studies, including those involving animals, have demonstrated that Ethylhexyl Dimethyl PABA(Escalol 507) is toxic to the following four organs: testis, epididymis, spleen, and liver. In addition, experiments using human keratinocytes found that Ethylhexyl Dimethyl PABA(Escalol 507) inhibits cell growth and DNA synthesis at low concentrations, and halted the cell cycle of MM96L cells (human melanoma cell line) at the G1 phase. Despite limited clinical data in humans, many studies have confirmed increased mutagenicity of Ethylhexyl Dimethyl PABA(Escalol 507) following exposure to sunlight, which suggests that this molecule is likely to contribute to onset of sun-induced cancer despite protecting the skin through absorption of UVB. For risk assessment, the no observed adverse effect level (NOAEL) chosen was 100 mg/kg bw/day in a 4 weeks oral toxicity study. Systemic exposure dosage (SED) was 0.588 mg/kg bw/day for maximum use of Ethylhexyl Dimethyl PABA(Escalol 507) in cosmetics. Based on the risk assessment and exposure scenarios conducted in this study, the margin of safety (MOS) was calculated to be 180.18 for a sunscreen containing 8% Ethylhexyl Dimethyl PABA(Escalol 507), which is the maximum level allowed by the relevant domestic authorities. Ethylhexyl Dimethyl PABA(Escalol 507) Ethylhexyl Dimethyl PABA(Escalol 507) is classified as : Uv absorber Uv filter CAS Number 21245-02-3 EINECS/ELINCS No: 244-289-3 Restriction (applies to EU only): VII/21 COSING REF No: 33875 INN Name: padimate-O Chem/IUPAC Name: 2-Ethylhexyl 4-(dimethylamino)benzoate Ethylhexyl Dimethyl PABA(Escalol 507) Icky ALSO-CALLED-LIKE-THIS: Padimate O, Octyl Dimethyl PABA, Eusolex 6007 WHAT-IT-DOES: sunscreen Official CosIng Information Details Ethylhexyl Dimethyl PABA(Escalol 507) is a chemical sunscreen agent that protects in the UVB range (290-320 nm) with a peak absorbance at 312nm. Other than that, we struggle to write anything positive about this guy, as it is photo unstable (looses 10% efficacy in 20 mins and 50% in 85 mins), not an unfrequent allergen in sunscreens and shows some endocrine effect in animal studies. All this does not mean that it is not considered safe as used, it is (and is approved up to 8% in the EU and US and up to 3% in Japan), but we do think that there are plenty of other and better UV filters out there. Ethylhexyl Dimethyl PABA(Escalol 507) Messages Overview(active tab) Safety Resources What Is It? Ethylhexyl Dimethyl PABA(Escalol 507) is a yellowish, oily liquid. In cosmetics and personal care products, Ethylhexyl Dimethyl PABA(Escalol 507) is used in the formulation of sunscreen products, shampoos, conditioners, hair sprays, makeup, and bath and skin products. When it is used in sunscreen drug products, Ethylhexyl Dimethyl PABA(Escalol 507) is called Padimate O. Why is it used in cosmetics and personal care products? Padimate O, when applied to the skin, absorbs UV rays. In addition to causing sunburn, UV radiation is a significant cause of premature aging of the skin and contributes to the development of melanoma and other forms of skin cancer. Ethylhexyl Dimethyl PABA(Escalol 507) can also be used to protect cosmetics and personal care products from deterioration by absorbing, UV rays Scientific Facts: Ethylhexyl Dimethyl PABA(Escalol 507), or Octyl Dimethyl para-Aminobenzoic Acid (PABA), absorbs ultraviolet radiation and converts it into less damaging infrared radiation (heat). Abstract Ethylhexyl Dimethyl PABA(Escalol 507)-aminobenzoic acid (PABA) is an oily yellow liquid derivative of water-soluble PABA commonly used in sunscreen. Ethylhexyl Dimethyl PABA(Escalol 507) is widely used as an ingredient in many cosmetics at an average concentration of 1.25% (0.5–2.0%) in Korea. Previous studies, including those involving animals, have demonstrated that Ethylhexyl Dimethyl PABA(Escalol 507) is toxic to the following four organs: testis, epididymis, spleen, and liver. In addition, experiments using human keratinocytes found that Ethylhexyl Dimethyl PABA(Escalol 507) inhibits cell growth and DNA synthesis at low concentrations, and halted the cell cycle of MM96L cells (human melanoma cell line) at the G1 phase. Despite limited clinical data in humans, many studies have confirmed increased mutagenicity of Ethylhexyl Dimethyl PABA(Escalol 507) following exposure to sunlight, which suggests that this molecule is likely to contribute to onset of sun-induced cancer despite protecting the skin through absorption of UVB. For risk assessment, the no observed adverse effect level (NOAEL) chosen was 100 mg/kg bw/day in a 4 weeks oral toxicity study. Systemic exposure dosage (SED) was 0.588 mg/kg bw/day for maximum use of Ethylhexyl Dimethyl PABA(Escalol 507) in cosmetics. Based on the risk assessment and exposure scenarios conducted in this study, the margin of safety (MOS) was calculated to be 180.18 for a sunscreen containing 8% Ethylhexyl Dimethyl PABA(Escalol 507), which is the maximum level allowed by the relevant domestic authorities. Keywords: Ethylhexyl Dimethyl PABA(Escalol 507), Cosmetics, Sunscreen, Risk assessment, Toxicity Go to: INTRODUCTION Ethylhexyl Dimethyl PABA(Escalol 507) (CAS No. 21245-02-3) is an organic derivative of water-soluble PABA (4-aminobenzoic acid) included in sunscreen and other cosmetics. It is a yellow water-insoluble oily liquid with an ester bond formed by condensation of 2-ethylhexanol and dimethylaminobenzoic acid (Fig. 1). Ethylhexyl Dimethyl PABA(Escalol 507) is also known as padimate O, OD-PABA, or octyl dimethyl p-aminobenzoate (Table 1). The Ministry of Food and Drug Safety (MFDS) and US Food and Drug Administration (FDA) mandate that its concentration in any cosmetic product shall not exceed 8% (1). Previous animal studies showed that high concentrations of Ethylhexyl Dimethyl PABA(Escalol 507) may be toxic to the epididymis and caution should be exercised when administering this substance to infants younger than six months of age due lack of understanding of its metabolism and absorption (2). Previous risk assessment data for Ethylhexyl Dimethyl PABA(Escalol 507) includes potential toxicity data and national and international regulations only. The present study summarizes a risk assessment that included determination of the margin of safety (MOS) at concentrations in cosmetics allowed by domestic authorities, a summary of existing experimental toxicity data, and exposure data associated with the amount of use in domestic cosmetic products. An external file that holds a picture, illustration, etc. Object name is tr-35-131f1.jpg Fig. 1 Chemical structure of Ethylhexyl Dimethyl PABA(Escalol 507). Table 1 Ethylhexyl Dimethyl PABA(Escalol 507) nomenclature and classification CAS No. 21245-02-3 EINECS No. 244-289-3 INCI name Ethylhexyl Dimethyl PABA(Escalol 507) IUPAC name 2-Ethylhexyl 4-(dimethylamino)benzoate Synonyms Padimate O Octyl dimethyl p-aminobenzoate, Octyl dimethyl PABA 2-Ethylhexyl p-(dimethylamino)benzoate OD-PABA Adopted from Hazardous Substances Data Bank (HSDB) & ChemIDplus (2). Go to: PHYSICAL AND CHEMICAL PROPERTIES The range of purities of Ethylhexyl Dimethyl PABA(Escalol 507) used as a raw material for cosmetics is approximately 98–99.5%. It is an oily yellow liquid state with oil characteristics. It has a molecular weight of 277.4053. It is soluble in alcohol, and strong acid and base, but is insoluble in water and acetic acid (Table 2). Table 2 Chemico-physical properties of Ethylhexyl Dimethyl PABA(Escalol 507) Physical property Yellow liquid with oil characteristics Molecular weight 277.4053 pKa 6.027 Boiling point 387.8°C at 760 mmHg Melting point 242.5–243.5°C Ignition point 124.1°C Steam pressure 7.7 × 107 mmHg at 25°C Specific gravity 0.99 Solubility Dissolved in alcohol, HCl, KOH Not dissolved in acetic acid Dissolved in water at 25°C if 5.3 × 103 mg/L Density 1.0 ± 0.1 g/cm3 Adopted from HSDB (2). Go to: COSMETIC USE Ethylhexyl Dimethyl PABA(Escalol 507) is used in sunscreen and in a variety of beauty products. According to the Environmental Working Group (EWG) database, it is used in many products including lipstick, conditioner, shampoo, anti-aging agents, hair spray, and sunscreen. Use of Ethylhexyl Dimethyl PABA(Escalol 507) in non-cosmetic products has not been reported in Korea. According to a survey conducted by the MFDS the average concentration of Ethylhexyl Dimethyl PABA(Escalol 507) in cosmetic products is 1.25% (ranging from 0.5–2.0%). Go to: HAZARD IDENTIFICATION Single and repeated dose toxicity studies of Ethylhexyl Dimethyl PABA(Escalol 507) have identified various toxicities including skin irritation, reproductive toxicity, genotoxicity, and phototoxicity. Repeated dosing of experimental animals resulted in organ toxicity and organ pigmentation. The major proposed mechanism of Ethylhexyl Dimethyl PABA(Escalol 507) toxicity is DNA damage by light-modified Ethylhexyl Dimethyl PABA(Escalol 507). General toxicity In an acute toxicity study of Ethylhexyl Dimethyl PABA(Escalol 507), the LD50 in rats was 14,900 mg/kg (3) and no irritation was observed in a human patch test using white Vaseline® mixed with 8% Ethylhexyl Dimethyl PABA(Escalol 507). According to a report by the Scientific Committee on Cosmetology (SCC) (1999) (4), a 4-week oral administration study was conducted in rats in accordance with GLP principles. Ethylhexyl Dimethyl PABA(Escalol 507) was administered orally (by gavage) at doses of 0, 100, 300, and 1,000 mg/kg/day (Groups 1, 2, 3, and 4, respectively) to 10 male and female rats per group. An additional 5 male and 5 female rats were added to Groups 1 and 4 to evaluate the convalescence stage. No clinical symptoms were observed except salivation in Group 4 and decreased weight in Group 4 three to four weeks after administration, which did not normalize following the convalescence period. Gross inspections during autopsies of the animals found that the capsule of the spleen was severely degraded in one female in Group 4. A male in Group 4 (4/10) exhibited a softened testis and 8 males exhibited reduced testis size. No prostate, epididymis, or seminal vesicle abnormalities were observed. Three out of the five males in the Group 4 convalescence group exhibited reduced testis size. A female rat in Group 4 showed increased spleen weight, and the females in Groups 3 and 4 exhibited increased liver weight. Furthermore, the males in Group 4 exhibited liver weight gain and pituitary gland weight loss. Among the animals in the convalescence group, the males in Group 4 exhibited kidney weight gain, but showed no changes in testis or pituitary gland weights. Histopathological examinations showed moderate or moderately severe testicular atrophy in all males in Group 4 and epididymal edema in seven out of the ten males in Group 4. All males in Group 4 had spleen pigmentation, but spleen pigmentation was more conspicuous in the females in Group 3 and was extensive in the females in Group 4. The NOAEL was determined at 100 mg/kg/day based on pigmentation of the spleen (5). The SCC determined that this NOAEL may have been too conservative, so a NOAEL value of 300 mg/kg/day was assigned to Ethylhexyl Dimethyl PABA(Escalol 507) (4). No toxicity was observed in 20 rabbits administered 140 or 280 mg/kg/day of Ethylhexyl Dimethyl PABA(Escalol 507) for 13 weeks (4). Reproductive and developmental toxicity When 2 mL/kg daily Ethylhexyl Dimethyl PABA(Escalol 507) was applied to the skin of rats at 6 to 16 days of pregnancy, wavy ribs were observed on both sides of 7/56 fetuses and on one side of 2/56 fetuses. However, these observations were not attributed to Ethylhexyl Dimethyl PABA(Escalol 507) toxicity, as the rat species used in this study commonly exhibit wavy ribs (4). According to a report by Erol et al. (6), dermal exposure to OD-PABA did not affect pubertal development or thyroid function in female or male rats. As such, OD-PABA was not classified as an endocrine disrupting chemical. Mutagenicity/Genotoxicity In vivo micronucleus testing was conducted on mice to evaluate mutagenesis. Ethylhexyl Dimethyl PABA(Escalol 507) (5,000 mg/kg) was intraperitoneally injected into three groups of mice (n = 10 mice per group; 30, 48, or 72 hr), resulting in no mutagenesis (3). A chromosomal aberration test was performed in human lymphocytes. This assay is based on metabolic activation in response to the S9 mix. Ethylhexyl Dimethyl PABA(Escalol 507) was dissolved in ethanol at concentrations of 315 to 5,010 μg/mL. No chromosomal aberrations were observed (4). Carcinogenicity Ethylhexyl Dimethyl PABA(Escalol 507) is not considered carcinogenic per International Agency for Research on Cancer (IARC), Association Advancing Occupational and Environmental Health (ACGIH), US National Toxicology Program (NTP), and Occupational Safety and Health Administration (OSHA) (7). Ocular irritation Two percent Ethylhexyl Dimethyl PABA(Escalol 507) mixed with mineral oil was applied to the eyes of rabbits. No irritation was reported when both eyes are washed and left unattended (3). A slight irritation was observed in rabbit mucous membranes during a Draize test with 2% and 5% Ethylhexyl Dimethyl PABA(Escalol 507) in mineral oil (4). Skin irritation Five percent Ethylhexyl Dimethyl PABA(Escalol 507) mixed with mineral oil applied to rabbit skin did not cause irritation (3,8). In addition, a patch containing Ethylhexyl Dimethyl PABA(Escalol 507) dissolved in 4% white Vaseline® affixed to adult volunteers did not cause skin sensitization (3). No irritation was observed following application of 5% Ethylhexyl Dimethyl PABA(Escalol 507) to normal and damaged rabbit skin for 24 hr (4). A human patch test study showed no incidence of irritation following application of yellow soft paraffin with 5% Ethylhexyl Dimethyl PABA(Escalol 507) for 48 hr (4). When 1 mg/mL of estradiol was prescribed during the autumn and winter seasons to postmenopausal women (4 persons), women receiving hormone replacement therapy, women with sensitivity to Ethylhexyl Dimethyl PABA(Escalol 507), women with epilepsy, or women prescribed medications to control liver metabolism (aged between 54 and 63, body weight between 67 and 93 kg) along with Ethylhexyl Dimethyl PABA(Escalol 507) applied to their arm over a 10 cm2 area, daily for nine days, no skin irritation was observed (9). Skin sensitization Five percent Ethylhexyl Dimethyl PABA(Escalol 507) in mineral oil did not cause skin sensitization in guinea pigs. In addition, 50 μL of 0.1% Ethylhexyl Dimethyl PABA(Escalol 507) in saline was injected into ten guinea pigs, followed by nine additional 0.1 mL injections administered across three weeks. The guinea pigs did not exhibit sensitization when challenged with a 0.05 mL dose after a 12-week resting phase (4). No skin sensitization was observed in humans following application of 1.5% or 4% Ethylhexyl Dimethyl PABA(Escalol 507) mixed with white Vaseline® (3). Furthermore, 15 volunteers were instructed to apply soft paraffin containing 4% Ethylhexyl Dimethyl PABA(Escalol 507) for three weeks, followed by a challenge application after a two week rest phase, after which no skin sensitization was observed. Consistent with this result, 150 individuals subjected to a patch test with 7% Ethylhexyl Dimethyl PABA(Escalol 507) with 3% oxybenzone did not exhibit skin sensitization (4). Another study showed that application of soft paraffin containing 7% Ethylhexyl Dimethyl PABA(Escalol 507) to 156 individuals did not cause sensitization (4). Finally, a slight stinging reaction was reported during the induction period when a mixture of 3% benzophenone and 8% Ethylhexyl Dimethyl PABA(Escalol 507) was applied to 90 individuals, but no skin sensitization was observed (4). Phototoxicity/Photosensitization Ten guinea pigs had their ear hair removed and a mixture of 3% oxybenzone and 7% Ethylhexyl Dimethyl PABA(Escalol 507) was applied to one ear several times, and 8-methoxypsoralen was applied to the ears of two guinea pigs as a positive control. The guinea pigs were then exposed to UV radiation for two hours. No phototoxicity was observed. Furthermore, no phototoxicity was observed when Ethylhexyl Dimethyl PABA(Escalol 507) was applied to the posterior of guinea pigs for 2 hr followed by irradiation of 3 J/cm2 at 320–400 nm (4). No phototoxicity was observed in 26 individuals who were tested with 3% oxybenzone and 7% Ethylhexyl Dimethyl PABA(Escalol 507) (4). Furthermore, no phototoxicity was observed when 5% Ethylhexyl Dimethyl PABA(Escalol 507) in ethanol was applied and the site was irradiated with 30 J (4). Patch testing with a mixture of 2% oxybenzone and 7% Ethylhexyl Dimethyl PABA(Escalol 507) for 24 hr was conducted on ten white-skin individuals. Following removal of the patch, the site was irradiated with UVA for 12 min followed by 1 MED (minimal erythema dose) of UVB. No phototoxicity was observed in this study (4). Furthermore, human subjects treated every 26 hr with an emulsion of stearic acid (3%), water (91%), and 4% Ethylhexyl Dimethyl PABA(Escalol 507) showed no phototoxicity. Ethylhexyl Dimethyl PABA(Escalol 507) is harmless unless it is exposed to light. However, once activated by light, it directly damages DNA. Ethylhexyl Dimethyl PABA(Escalol 507) in commercially available sunscreen products can be activated by UVA, and to a greater extent by UVB, when exposed to sunlight (10). Toxicokinetics To determine whether a new metered-dose topical aerosol (MDTA) medication containing Ethylhexyl Dimethyl PABA(Escalol 507) as a skin penetration enhancer could enhance transdermal delivery of estradiol, estradiol MDTA containing Ethylhexyl Dimethyl PABA(Escalol 507) was applied to the abdomens of postmenopausal women for nine days and the levels of estradiol and estrone in the blood were measured daily via radioimmunoassay. Following MDTA treatment, 1 mg of estradiol sprayed onto three adjacent areas of skin (10 cm2) on the abdomens of each subject did not induce skin irritation. Blood estradiol concentrations were measured in four women (aged between 54 and 63 years, body weight between 67 and 93 kg). The average blood estradiol concentration was 53 pg/mL across the 9-day study period, which was significantly greater than the reference value of 13 pg/mL. (p < 0.001). This test confirmed that the MDTA containing Ethylhexyl Dimethyl PABA(Escalol 507) enhanced transdermal delivery of estradiol (9). 14C-labelled Ethylhexyl Dimethyl PABA(Escalol 507) in ethanol was applied to 100 cm2 of the forearms of each of four male and female subjects. The forearms were then covered with gauze for 24 hr after the ethanol completely evaporated. Blood was collected after 0, 2, 4, 8, 24, and 72 hr and urine was collected for 24 hr. No radioactivity was found in the blood samples while 2.45% and 1.18% radioactivity were found in the urine samples of the male and female subjects, respectively (average % of total radioactivity). The average radioactivity recovered after washing the skin at the application site was 95.7%. Assuming that 0.5 mg/cm2 was applied at a concentration of 8% to 1.8 m2, the total amount absorbed was 13 mg, or 0.2 mg/kg (4). An oil-in-water emulsion lotion was used for an in vitro percutaneous penetration test, and guinea pig and human skin were used as the membranes. HEPES-buffered Hank’s balanced salt solution containing gentamycin sulfate and bovine serum albumin was used as the aqueous solution in the receiving chamber. The total absorption rate of Ethylhexyl Dimethyl PABA(Escalol 507) transferred to the receiving chamber and the skin was 12.7 ± 2.5%. Evaluation of Ethylhexyl Dimethyl PABA(Escalol 507) metabolism was also included in this test. Guinea pig skin hydrolyzed approximately 13–35% of Ethylhexyl Dimethyl PABA(Escalol 507) transferred to the aqueous solution through esterase activity, while human skin hydrolyzed 37% of Ethylhexyl Dimethyl PABA(Escalol 507) (11). The value used for skin absorption in humans for the risk assessment was 2.45% based on the limited skin absorption data. Miscellaneous materials (including clinical data) Cell tests confirmed that Ethylhexyl Dimethyl PABA(Escalol 507) inhibited cell growth and DNA synthesis, and delayed cycle progression at 25–100 mg/mL. The CI80-13S cell line, a model of mitochondrial dysfunction, showed greater cell growth inhibition in response to ethylhexyl p-methoxycinnamate (EHMC) and PABA than the other cell lines. The pretreatment of MM96L with ethidium bromide (EtBr), which serve as mitochondrial inhibitors, followed by sunscreen treatment, resulted in apoptosis with increased uptake of ethidium bromide (12). When keratinocytes exposed to 5 MED of sunlight were treated with sunscreen containing Ethylhexyl Dimethyl PABA(Escalol 507) (SPF 15), the number of DNA strand breaks observed here was at least 75 times higher than that in cells treated with sunscreen that did not contain Ethylhexyl Dimethyl PABA(Escalol 507) (13). MCF-7, a human breast cancer cell line, was used to measure the estrogenic activity of Ethylhexyl Dimethyl PABA(Escalol 507). Cell proliferation rates were evaluated by attaching the estrogen receptor of Ethylhexyl Dimethyl PABA(Escalol 507), and 17β-estradiol was used as a positive control. The EC50 values for cell proliferation were 1.2 pM and 2.63 pM for 17β-estradiol and Ethylhexyl Dimethyl PABA(Escalol 507), respectively (14). Go to: DOSE-RESPONSE ASSESSMENT After toxicological data were reviewed to determine the optimal toxicity reference value, the NOAEL of Ethylhexyl Dimethyl PABA(Escalol 507) was selected from a 4-week repeated dose toxicity study in rats. Ethylhexyl Dimethyl PABA(Escalol 507) dissolved in corn oil was administered to rats at concentrations of 0, 100, 300, and 1,000 mg/kg/day for four weeks by gavage, followed by four weeks of convalescence to assess the durability or reversibility of toxic effects. The results following the first four weeks showed toxicities such as increased weight and histological changes in the testes, epididymis, spleen, and liver. The assessment of reversible toxicity following four weeks of convalescence confirmed the absence of toxicity except for semen reduction in the epididymis, which was only observed in the treatment group given 1,000 mg/kg/day of Ethylhexyl Dimethyl PABA(Escalol 507). Pigmentation of the spleen was observed among males subjected to high concentrations of Ethylhexyl Dimethyl PABA(Escalol 507). This observation was more conspicuous among females treated with 300 and 1,000 mg/kg/day of Ethylhexyl Dimethyl PABA(Escalol 507). Based on the pigmentation of the spleen, NOAEL was determined to be 100 mg/kg/day (5) (Table 3). The NOAEL was based on animal testing data and Ethylhexyl Dimethyl PABA(Escalol 507) was not considered to be of concern if the MOS was 100 or above. Based on the MOS determined using the use limit of Ethylhexyl Dimethyl PABA(Escalol 507) among domestic cosmetic products, the health risk of Ethylhexyl Dimethyl PABA(Escalol 507) for use of sunscreen was 180.18, which is significantly higher than 100, which confirmed the safety of Ethylhexyl Dimethyl PABA(Escalol 507). Go to: CONCLUSION Ethylhexyl Dimethyl PABA(Escalol 507) is an organic derivative of water-soluble PABA (4-aminobenzoic acid) used as an ingredient in sunscreen and other cosmetics. Ethylhexyl Dimethyl PABA(Escalol 507) induced pigmentation of the spleen in a four-week oral administration toxicity test in rats, and the NOAEL derived from this study was 100 mg/kg/day. No significant reproductive toxicity, genotoxicity, carcinogenicity, skin sensitization, skin irritation, or phototoxicity was observed in response to Ethylhexyl Dimethyl PABA(Escalol 507) administration. The optimal NOAEL for the risk assessment was determined to be 100 mg/kg/day based on a four-week repeated toxicity study in rats. The SED of Ethylhexyl Dimethyl PABA(Escalol 507) was 0.588. The risk characterization demonstrated that Ethylhexyl Dimethyl PABA(Escalol 507) is safe to use in cosmetics in accordance with current MFDS regulations because the MOS exceeded 100 even at the maximum permitted concentration in cosmetics (8%). However, the toxicological data used in the risk assessment are limited, and if new toxicological data are reported, further assessments should be performed as appropriate. Abstract Ethylhexyl Dimethyl PABA(Escalol 507)-aminobenzoic acid (PABA) is an oily yellow liquid derivative of water-soluble PABA commonly used in sunscreen. Ethylhexyl Dimethyl PABA(Escalol 507) is widely used as an ingredient in many cosmetics at an average concentration of 1.25% (0.5–2.0%) in Korea. Previous studies, including those involving animals, have demonstrated that Ethylhexyl Dimethyl PABA(Escalol 507) is toxic to the following four organs: testis, epididymis, spleen, and liver. In addition, experiments using human keratinocytes found that Ethylhexyl Dimethyl PABA(Escalol 507) inhibits cell growth and DNA synthesis at low concentrations, and halted the cell cycle of MM96L cells (human melanoma cell line) at the G1 phase. Despite limited clinical data in humans, many studies have confirmed increased mutagenicity of Ethylhexyl Dimethyl PABA(Escalol 507) following exposure to sunlight, which suggests that this molecule is likely to contribute to onset of sun-induced cancer despite protecting the skin through absorption of UVB. For risk assessment, the no observed adverse effect level (NOAEL) chosen was 100 mg/kg bw/day in a 4 weeks oral toxicity study. Systemic exposure dosage (SED) was 0.588 mg/kg bw/day for maximum use of Ethylhexyl Dimethyl PABA(Escalol 507) in cosmetics. Based on the risk assessment and exposure scenarios conducted in this study, the margin of safety (MOS) was calculated to be 180.18 for a sunscreen containing 8% Ethylhexyl Dimethyl PABA(Escalol 507), which is the maximum level allowed by the relevant domestic authorities.
ETHYLHEXYL DIMETHYL PABA ( OCTYL DIMETHYL PABA)
ETHYLHEXYL ETHYLHEXANOATE, N° CAS : 7425-14-1. Nom INCI : ETHYLHEXYL ETHYLHEXANOATE. Nom chimique : 2-Ethylhexyl 2-ethylhexanoate. N° EINECS/ELINCS : 231-057-1. Ses fonctions (INCI). Emollient : Adoucit et assouplit la peau
ETHYLHEXYL ETHYLHEXANOATE
ETHYLHEXYL HYDROXYSTEARATE. N° CAS : 29710-25-6 / 29383-26-4. Nom INCI : ETHYLHEXYL HYDROXYSTEARATE. Nom chimique : 2-Ethylhexyl 12-hydroxyoctadecanoate. N° EINECS/ELINCS : 249-793-7. Classification : Huile estérifiée. Ses fonctions (INCI). Emollient : Adoucit et assouplit la peau
ETHYLHEXYL HYDROXYSTEARATE
ETHYLHEXYL HYDROXYSTEARATE BENZOATE, N° CAS : 199277-69-5, Nom INCI : ETHYLHEXYL HYDROXYSTEARATE BENZOATE, Nom chimique : 2-Ethylhexyl 12-benzoyloxyoctadecanoate, Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau, Agent d'entretien de la peau : Maintient la peau en bon état
ETHYLHEXYL HYDROXYSTEARATE BENZOATE
ETHYLHEXYL ISOPALMITATE, N° CAS : 93843-32-4, Nom INCI : ETHYLHEXYL ISOPALMITATE. Nom chimique : 2-Ethylhexyl isohexadecanoate. N° EINECS/ELINCS : 299-112-2. Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau
ETHYLHEXYL ISOPALMITATE
ETHYLHEXYL ISOSTEARATE, N° CAS : 81897-25-8, Nom INCI : ETHYLHEXYL ISOSTEARATE. Nom chimique : Isooctadecanoic acid, 2-ethylhexyl ester. Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau
ETHYLHEXYL ISOSTEARATE
ETHYLHEXYL ISONONANOATE, N° CAS : 71566-49-9, Nom INCI : ETHYLHEXYL ISONONANOATE. Nom chimique : 2-Ethylhexyl isononanoate. N° EINECS/ELINCS : 275-637-2. Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau
Ethylhexyl isononanoate
ETHYLHEXYL LAURATE, N° CAS : 20292-08-4, Nom INCI : ETHYLHEXYL LAURATE. Nom chimique : 2-Ethylhexyl laurate. N° EINECS/ELINCS : 243-697-9. Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau
ETHYLHEXYL LAURATE
ETHYLHEXYL METHACRYLATE, N° CAS : 688-84-6, Nom INCI : ETHYLHEXYL METHACRYLATE. Nom chimique : 2-Ethylhexyl Methacrylate. Ses fonctions (INCI) :Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles
ETHYLHEXYL METHACRYLATE
SYNONYMS 2-ethylhexyl 4-methoxycinnamate;2-Ethylhexyl p-methoxycinnamate;2-Ethylhexyl-4-methoxycinnamat;2-Propenoic acid, 3-(4-methoxyphenyl)-, 2-ethylhexyl ester;3-(4-Methoxyphenyl)-2-propenoic acid 2-ethylhexyl ester;4-Methoxycinnamate de 2-ethylhexyle CAS NO:5466-77-3
ETHYLHEXYL METHOXYCINNAMATE
ETHYLHEXYL METHOXYCINNAMATE, N° CAS : 5466-77-3, Nom INCI : ETHYLHEXYL METHOXYCINNAMATE. Nom chimique : 2-Ethylhexyl 4-methoxycinnamate. N° EINECS/ELINCS : 226-775-7. Ses fonctions (INCI) : Absorbant UV : Protège le produit cosmétique contre les effets de la lumière UV. Filtre UV : Permet de filtrer certains rayons UV afin de protéger la peau ou les cheveux des effets nocifs de ces rayons.
ETHYLHEXYL MYRISTATE
ETHYLHEXYL OLEATE, N° CAS : 26399-02-0. Nom INCI : ETHYLHEXYL OLEATE. N° EINECS/ELINCS : 247-655-0. Ses fonctions (INCI). Emollient : Adoucit et assouplit la peau
ETHYLHEXYL OLEATE
Ethylhexyl Oleate is designed for use in a wide variety of applications where the properties of a high quality ester made from oleic acid are required.
Ethylhexyl Oleate is intended for uses where excellent color, stability and odor characteristics and natural origin are desired.
Ethylhexyl Oleate is clear liquid at room temperatures with a melting point around -20 ºC.

CAS Number: 26399-02-0
EC Number: 247-655-0
Molecular Formula: C26H50O2
Molecular Weight: 394.679

Ethylhexyl Oleate finds application in personal care formulations as an emollient or in lubricants as a friction modifier in engine oils or as a feed for further modification.
Ethylhexyl Oleate has been used as a viscocity control agent in personal care for products with high fat or wax contents, and for some other uses in lubricants and cosmetics such as bath oils, hair preparations and creams.

Ethylhexyl Oleate is Ethylhexyl Oleate made from our oleic acid and designed for use in a wide variety of applications where the properties of a high quality ester are required.
Ethylhexyl Oleate is intended for uses where excellent color, stability and odor characteristics and natural origin are desired.

Ethylhexyl Oleate finds application in personal care formulations as an emollient or in lubricants as a friction modifier in engine oils or as a feed for further modification.
Ethylhexyl Oleate has been used as a viscocity control agent in personal care for products with high fat or wax contents, and for some other uses in lubricants and cosmetics such as bath oils, hair preparations and creams.

Ethylhexyl Oleate is a branched mono-saturated fatty acid ester obtained from 2-ethylhexanol and oleic fatty acid, mainly from palm oil.
Clear liquid at room temperatures with a melting point around -20 ºC.

Ethylhexyl Oleate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Ethylhexyl Oleate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Global Ethylhexyl Oleate Market: Introduction
Nowadays, the usage of synthetic esters as an intermediate has become a trend in many industries owing to Ethylhexyl Oleate superior properties.
Ethylhexyl Oleate is a monoester, is easy to emulsify, and has better lubricity & hydraulic stability as compared to other esters.

Ethylhexyl Oleate is produced from vegetable oils as well as from synthetic base oils.
The production of Ethylhexyl Oleate from vegetable oils is a high technology invention in term of environment-friendly products as compared to the production from mineral oils.

Alternative names of Ethylhexyl Oleate are – 9-octadecenoic acid (9Z), 9-Octadecenoic acid (Z), 2-Ethylhexyl ester, etc.
In terms of physical appearance, Ethylhexyl Oleate is clear liquid, white-colored compound, and having molecular formulae C26H50O2.
Ethylhexyl Oleate is a biodegradable compound, non-flammable liquid and miscible with hydrocarbons, ethers, and acetones.

In term of applications, Ethylhexyl Oleate act as an oxidizing agent, binding agent, intermediate, and antiwear additive for lubricants and metalworking fluids.
Ethylhexyl Oleate finds a wide range of applications across various end-use industries including automotive, adhesive & sealants, chemicals, and other manufacturing industries

Global Ethylhexyl Oleate Market Dynamics
The global Ethylhexyl Oleate market is prominently driven by the increasing industrial infrastructure across the world.
Advancement in end-use industries, expansion of production facilities and marketing strategies of companies is anticipated to generate the demand for intermediates/raw materials such as Ethylhexyl Oleate.

The increase in demand for biodegradable products is expected to propel the global Ethylhexyl Oleate market throughout the forecast period.

Further, end-users are emphasizing on improvement of processing efficiencies, demanding better technical performance in operations, and enhance environmental safety.
Attributing to these factors, the demand for synthetic esters i.e. Ethylhexyl Oleate is projected to upsurge.
Conversely, the availability of substitutes such as 2-Ethylhexyl Tallowate, methyl esters, etc. is expected to restrain the global Ethylhexyl Oleate market over the forecast period.

Aligned with the global trend of sustainability, Ethylhexyl Oleate is making way, among other biodegradable products, emerging as a key trend for global Ethylhexyl Oleate market.

Global 2-Etylhexyl Oleate Market: Regional Outlook
The production of Ethylhexyl Oleate varies from region to region, which depends on the local feedstock availability.
In term of Ethylhexyl Oleate consumption, South East Asia Pacific is expected to be prominent region, and is projected to grow with a healthy CAGR in near future.

In addition, North America and Europe are also secured their position in the global Ethylhexyl Oleate market from past few years.
Expansion of end-use industries in the U.S., Canada, Germany, UK, Australia, etc. is influencing factor for the growth of North America and Europe Ethylhexyl Oleate market.

Furthermore, the Middle East & Africa and Oceania regions estimated to hold less than one-fourth market share in the global Ethylhexyl Oleate market and is projected to grow with a moderate growth rate during the forecast period.

Uses of Ethylhexyl Oleate:
Emollient:
Softener and conditioner

Industry Uses of Ethylhexyl Oleate:
Ethylhexyl Oleate is used in the following products: washing & cleaning products, metal surface treatment products, textile treatment products and dyes, polymers, pH regulators and water treatment products and lubricants and greases.
Ethylhexyl Oleate is used in the following areas: formulation of mixtures and/or re-packaging.

Ethylhexyl Oleate is used for the manufacture of: chemicals and textile, leather or fur.
Release to the environment of Ethylhexyl Oleate can occur from industrial use: in processing aids at industrial sites and in the production of articles.

Other Industry Uses:
Adhesives and sealant chemicals
Functional fluids (open systems)
Lubricants and lubricant additives
Processing aids, specific to petroleum production
Solvents (for cleaning and degreasing)
Lubricating agent
Surface active agents
Washing and cleaning products
Lubricants and greases
Polishes and waxes
Textile treatment products
Dyes and polymers.

Consumer Uses of Ethylhexyl Oleate:
Ethylhexyl Oleate is used in the following products: washing & cleaning products, lubricants and greases, adhesives and sealants, polishes and waxes, textile treatment products and dyes and polymers.
Release to the environment of Ethylhexyl Oleate can occur from industrial use: in the production of articles.
Other release to the environment of Ethylhexyl Oleate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).

Other Consumer Uses:
Adhesives and sealants
Cleaning and furnishing care products
Lubricants and greases
Paints and coatings
Lubricants and lubricant additives
Lubricating agent
Surface active agents

Widespread uses by professional workers of Ethylhexyl Oleate:
Ethylhexyl Oleate is used in the following products: washing & cleaning products and polishes and waxes.
Ethylhexyl Oleate is used in the following areas: formulation of mixtures and/or re-packaging.

Ethylhexyl Oleate is used for the manufacture of: chemicals.
Other release to the environment of Ethylhexyl Oleate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).

Ethylhexyl Oleate is classified as:
Cosmetics - Emollient

Cosmetic formulations of Ethylhexyl Oleate:
Skin conditioning, emollient

General Manufacturing Information of Ethylhexyl Oleate:

Industry Processing Sectors:
Fabricated Metal Product Manufacturing
Petroleum Lubricating Oil and Grease Manufacturing
Printing Ink Manufacturing
Printing and Related Support Activities
Wholesale and Retail Trade

Identifiers of Ethylhexyl Oleate:
CAS Number: 26399-02-0
Chem/IUPAC Name: Ethylhexyl Oleate
EINECS/ELINCS No: 247-655-0
COSING REF No: 33889

Display Name: Ethylhexyl Oleate
EC Number: 247-655-0
EC Name: Ethylhexyl Oleate
CAS Number: 26399-02-0
Molecular formula: C26H50O2
IUPAC Name: 2-ethylhexyl octadec-9-enoate

Molecular Formula: C26H50O2
Average mass: 394.674 Da
Monoisotopic mass: 394.381073 Da
ChemSpider ID: 4942537

Catalog Number: ACM26399020
Product Name: Ethylhexyl Oleate
CAS: 26399-02-0
Category: Heterocyclic Organic Compound
Molecular Formula: C26H50O2
Molecular Weight: 394.679
Density: 0.867 g/cm³

Properties of Ethylhexyl Oleate:
Molecular Weight: 394.7
XLogP3-AA: 10.7
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 22
Exact Mass: 394.381080833
Monoisotopic Mass: 394.381080833
Topological Polar Surface Area: 26.3 Ų
Heavy Atom Count: 28
Complexity: 348
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 1
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Ethylhexyl Oleate:
Acid Value: 1.0 Max
Saponification Value: 135 - 145
Hydroxyl Value: 1.0 Max
Color: 5 Gard Max
Moisture: 0.3% Max
Solubility: Insoluble
Insolubility: in water
Molecular weight: 394.69

Synonyms of Ethylhexyl Oleate:
Ethylhexyl Oleate
26399-02-0
ethylhexyl oleate
9-Octadecenoic acid (9Z)-, 2-ethylhexyl ester
2-Ethylhexanol oleic acid ester
2-ETHYLHEXYL (9Z)-OCTADEC-9-ENOATE
9-Octadecenoic acid (Z)-, 2-ethylhexyl ester
R34927QY59
UNII-R34927QY59
2-ethylhexyloleate
2-ethylhexyl (Z)-octadec-9-enoate
EINECS 247-655-0
SABODERM EO
SYMPATENS-EO
DUB OO
EC 247-655-0
AEC ETHYLHEXYL OLEATE
Oleic acid 2-ethylhexyl ester
SCHEMBL333602
Oleic acid, 2-ethylhexyl ester
ETHYLHEXYL OLEATE [INCI]
DTXSID90893468
(+/-)-ETHYLHEXYL OLEATE
BBA39902
2-ETHYLHEXYL 2-OCTADECENOATE
ETHYLHEXYL OLEATE, (+/-)-
AS-66491
2-OCTADECENOIC ACID, 2-ETHYLHEXYL ESTER
Q27287724
(9Z)-9-Octadécénoate de 2-éthylhexyle [French] [ACD/IUPAC Name]
247-655-0 [EINECS]
26399-02-0 [RN]
2-Ethylhexyl (9Z)-9-octadecenoate [ACD/IUPAC Name]
2-Ethylhexyl (9Z)-octadec-9-enoate
Ethylhexyl Oleate
2-Ethylhexyl-(9Z)-9-octadecenoat [German] [ACD/IUPAC Name]
9-Octadecenoic acid, 2-ethylhexyl ester, (9Z)- [ACD/Index Name]
ETHYLHEXYL OLEATE
2-Ethylhexyl 9-octadecenoate [ACD/IUPAC Name]
2-ethylhexyloleate
9-Octadecenoic acid [ACD/IUPAC Name]
9-Octadecenoic acid (9Z)-, 2-ethylhexyl ester
9-Octadecenoic acid (Z)-, 2-ethylhexyl ester
MFCD00072286
OLEIC ACID, 2-ETHYLHEXYL ESTER
ETHYLHEXYL PALMITATE
Ethylhexyl palmitate is a mixture of a fatty alcohol and palmitic acid that functions in cosmetics products as an emollient (meaning it can soften and smooth skin), texture enhancer, and solvent in amounts from 2-50%, depending on the type of formula and desired aesthetics.
Ethylhexyl palmitate improves the look of skin, particularly dry skin, by helping reduce moisture loss from its upper layers.
As a solvent, Ethylhexyl palmitate helps solubilize other ingredients, helping active ingredients more readily penetrate skin.

CAS: 16958-85-3
MF: C24H48O2
MW: 368.64
EINECS: 241-028-5

Ethylhexyl palmitate helps sunscreen active ingredients such as avobenzone and ethylhexyl triazone disperse and remain evenly suspended in a formula.
Ethylhexyl palmitate has a feel like some silicones and silicone derivatives, making it an alternative to those ingredients in certain formulations.
There’s no research indicating this ingredient, which may be synthetic, plant-, or animal-derived, is a problem for skin.
Ethylhexyl palmitate, or octyl palmitate, is the fatty acid ester derived from 2-ethylhexanol and palmitic acid.
Ethylhexyl palmitate is commonly used in cosmetic formulations.

Ethylhexyl palmitate is a derivative of palm oil often used as an organic replacement to silicone.
Ethylhexyl palmitate has a 'dry-slip' feel that is very similar to silicone's texture.
Ethylhexyl palmitate is found in many skin care products as an ingredient used to adjust the consistency.
Ethylhexyl Palmitate, also called Octyl Palmitate, is a clear, colorless, practically odorless liquid.
Ethylhexyl palmitate is a white, crystalline, wax-like substance.
Ethylhexyl palmitate is a colorless, almost odorless, liquid.

In cosmetics and personal care products, the Palmitates are used in a wide spectrum of products.
Ethylhexyl palmitate, also known as octyl palmitate, is an ester of 2-ethyl hexanol and palmitic acid.
Ethylhexyl palmitate is a fatty acid found naturally in plants and animals.
Ethylhexyl palmitate is a derivative of palm oil.
Ethylhexyl palmitate comes as a clear, colorless and odorless liquid, but according to source it also comes as an amber-colored liquid.

Ethylhexyl Palmitate (2-ethylhexyl palmitate) is an ester of 2-ethylhexanol and palmitic acid, a multifunctional skincare ingredient that improves the skin feel of the final product.
Ethylhexyl palmitate's the perfect replacement for mineral oils like petrolatum.
This multi-purpose ester provides a more decadent skin feel and imparts “mid-feel” to emulsion during rub-out.
Ethylhexyl Palmitate is a non-occlusive emollient with medium spreading properties.
In addition, Ethylhexyl palmitate may act as a carrying agent and solvent for other ingredients, fixative for fragrance, and pigment wetting agent in decorative cosmetics.

2-ETHYLHEXYL PALMITATE Chemical Properties
Boiling point: 414.2±13.0 °C(Predicted)
Density: 0.860±0.06 g/cm3(Predicted)
Solubility: Chloroform (Slightly), Hexanes (Slightly)
Form: Solid
Color: Off-White
LogP: 10.975 (est)
EPA Substance Registry System: Ethylhexyl palmitate (16958-85-3)

Ethylhexyl palmitate is a clear, colorless liquid at room temperature with a slightly fatty odor.
Ethylhexyl palmitate and 2-ethylhexanol are reacted in the presence of an acid catalyst to make the ester.
Ethylhexyl palmitate is a branched saturated fatty ester derived from ethylhexyl alcohol and palmitic acid.

Uses
Apart from being a natural option for solvent in any preparation, Ethylhexyl palmitate can also be used to replace silicone.
Ethylhexyl palmitate has a very light feel on the skin and is non-tacky also.
Ethylhexyl palmitate forms a thin film over the skin or hair, and it does not let skin lose its inherent moisture, which otherwise can be lost in the process of exposure to the harsh environment, such as wind, sunlight or pollutants.
Silicones have a “dry-slip” feel on the skin, meaning moisturized nongreasy skin, the Ethylhexyl palmitate also provides a similar effect.

That’s the reason Ethylhexyl palmitate is an ideal choice as a solvent as a carrying agent and fragrance fixative.
Pigments or colorants even dispersion is very much significant in case of any cosmetic preparation, Ethylhexyl palmitate should deliver uniform quality from the first to last use, at this point octyl palmitate is used to wet pigments and produce uniform dispersion.
Ethylhexyl palmitate is used in skincare products, sun pre/post care products, color cosmetics, and pressed powders.

Ethylhexyl palmitate is used in cosmetic formulations as a solvent, carrying agent, pigment wetting agent, fragrance fixative and emollient.
Ethylhexyl palmitate's dry-slip skinfeel is similar to some silicone derivatives.
Ethylhexyl palmitate is an ingredient that is used to improve the texture, feel, and the scent of skincare and cosmetic products.
Ethylhexyl palmitate functions as an emollient, solvent, and fragrance fixative.

Ethylhexyl palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid.
Ethylhexyl palmitate can be found in natural plant fragrances and also synthetically produced.
Ethylhexyl palmitate is the most common saturated fatty acid found in animals, plants and microorganisms, and is a major component of palm oil.
Ethylhexyl palmitate is a clear, colorless liquid at room temperature with a slightly fatty odor.
Ethylhexyl palmitate is insoluble in water but mildly dissolves in oils.
In cosmetics and skincare products, Ethylhexyl palmitate functions as an emollient, solvent, and fragrance fixative.

Moisture
As an emollient, Ethylhexyl palmitate helps to keep the skin moist and supple by reducing water loss from the top layers of the skin.
Emollients also act as lubricants by reducing friction when anything rubs against the skin.
Ethylhexyl palmitate is considered to be a non-occlusive emollient, which means it does not form a film on the surface of the skin.
Ethylhexyl palmitate is often used as an organic replacement to silicones in a cosmetic formulation because Ethylhexyl palmitate provides a dry-slip, silky feel that is very similar to how a silicone would feel.

While all skin types can benefit from emollients like Ethylhexyl palmitate, emollients are very beneficial for those who have dry, rough, and/or flaky skin.
Emollients can treat these symptoms, leaving the skin looking and feeling soft and smooth. In addition, emollients may be suitable for those that suffer from conditions such as eczema, psoriasis, or other inflammatory skin conditions.

Solvent
Ethylhexyl palmitate functions as a solvent by helping other ingredients dissolve.
Solvents can also increase the efficacy of active ingredients in a formulation by enhancing their absorption through the skin.

Appearance
Another function of ethylhexyl palmitate in cosmetics is as a pigment wetting agent.
Wetting agents work by reducing the interfacial tension between two different types of ingredients in a cosmetic formulation.
Wetting agents are useful in makeup as they improve the pigment or color distribution in the formulation.
Think about even eyeshadow or foundation pigment.

Fragrance
Lastly, ethylhexyl palmitate functions as a fragrance fixative in cosmetics and skincare products.
A fixative helps to equalize the volatile fragrance components making them last longer and remain more stable on the skin.

Synonyms
2-ETHYLHEXYL PALMITATE
29806-73-3
2-Ethylhexyl hexadecanoate
Elfacos EHP
Hexadecanoic acid, 2-ethylhexyl ester
Palmitic acid, 2-ethylhexyl ester
Ceraphyl 368
Wickenol 155
EINECS 249-862-1
AI3-31580
UNII-2865993309
EC 249-862-1
SCHEMBL15529
DTXSID3027958
Palmitic acid 2-ethylhexyl ester
Palmitic acid-2-ethylhexyl ester
(2-ETHYLHEXYL) PALMITATE
ETHYLHEXYL PALMITATE [INCI]
(+/-)-ETHYLHEXYL PALMITATE
ETHYLHEXYL PALMITATE [VANDF]
MFCD00072255
ETHYLHEXYL PALMITATE [WHO-DD]
AKOS016010384
ETHYLHEXYL PALMITATE, (+/-)-
AS-15135
CS-0063978
E1435
FT-0709066
D97727
EN300-1719134
A876381
J-017652
ETHYLHEXYL PALMITATE
Ethylhexyl Palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid.
Ethylhexyl palmitate, or octyl palmitate, is the fatty acid ester derived from 2-ethylhexanol and palmitic acid.
Ethylhexyl palmitate is a clear, colorless liquid at room temperature with a slightly fatty odor.


CAS Number: 29806-73-3
EC Number: 249-862-1
Chemical formula: C24H48O2
Chem/IUPAC Name: Octan-3-yl hexadecanoate, 2-Ethylhexyl Ester


Ethylhexyl Palmitate is a super common, medium-spreading emollient ester that gives richness to the formula and a mild feel during rubout.
Ethylhexyl Palmitate can be a replacement for mineral oil and is often combined with other emollients to achieve different sensorial properties.
Ethylhexyl palmitate has a feel like some silicones and silicone derivatives, making it an alternative to those ingredients in certain formulations.


There’s no research indicating Ethylhexyl Palmitate, which may be synthetic, plant-, or animal-derived, is a problem for skin.
Ethylhexyl palmitate is a fatty acid ester that is used as an emollient in cosmetic formulations.
Ethylhexyl Palmitate is a clear, colorless, liquid at room temperature bearing a faintly fatty smell.


Ethylhexyl Palmitate imparts a richness to a formula and can be a replacement for mineral oil.
Ethylhexyl palmitate is obtained from the reaction of palmitic acid, a very common fatty acid, with 2-ethyl hexanol, in the presence of an acid catalyst.
Ethylhexyl Palmitate is an ester of 2-ethylhexanol and palmitic acid. Ethylhexyl Palmitate's saponification value is 130 - 160.


Ethylhexyl Palmitate has medium spreading.
Ethylhexyl Palmitate can replace mineral oil in formulations.
Ethylhexyl palmitate, or octyl palmitate, is the fatty acid ester derived from 2-ethylhexanol and palmitic acid.


Ethylhexyl palmitate is a branched saturated fatty ester derived from ethylhexyl alcohol and palmitic acid.
Ethylhexyl palmitate is a clear, colorless liquid at room temperature with a slightly fatty odor.
Palmitic acid and 2-ethylhexanol are reacted in the presence of an acid catalyst to make the ester.


Ethylhexyl Palmitate is a clear colorless, practically odorless liquid.
Ethylhexyl Palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid.
Ethylhexyl Palmitate (2-ethylhexyl palmitate or Octyl palmitate) is an ester of 2-ethyl hexanol and palmitic acid, a multifunctional skincare ingredient that improves the skin feel of the final product.


Ethylhexyl Palmitate's an emollient ester and a perfect replacement for mineral oils like petrolatum.
Ethylhexyl Palmitate is a renewable palm derivative with a variety of uses in both personal care and industrial applications.
Ethylhexyl Palmitate is a clear low viscosity liquid with little odor.


Ethylhexyl palmitate provides slip and lubricity to skin preparations and is a good anti-tack agent in antiperspirants, creams, and lotions.
This multi-purpose ester provides a more decadent skin feel and imparts “mid-feel” to emulsion during rub-out.
Ethylhexyl palmitate has a feel like some silicones and silicone derivatives, making it an alternative to those ingredients in certain formulations.


There’s no research indicating this ingredient, which may be synthetic, plant-, or animal-derived, is a problem for skin.
Ethylhexyl Palmitate is oil soluble, and is supplied as a clear to off-white liquid.
Ethylhexyl palmitate, also known as octyl palmitate, is an ester of 2-ethyl hexanol and palmitic acid.


Palmitic acid is a fatty acid found naturally in plants and animals.
Ethylhexyl Palmitate is a derivative of palm oil.
Ethylhexyl Palmitate comes as a clear, colorless and odorless liquid, but according to source it also comes as an amber-colored liquid.


Ethylhexyl Palmitate is ester of 2-ethylhexanol and palmitic acid.
Ethylhexyl Palmitate can be added to formulas as is, add to oil phase, use level 2-50%.
Ethylhexyl Palmitate is a branched saturated fatty acid ester obtained from 2-ethylhexanol and palmitic fatty acid, from palm oil.


Ethylhexyl Palmitate is clear liquid at room temperatures with a melting point around -30 ºC.
Ethylhexyl Palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid.
Ethylhexyl Palmitate is an alternate to silicone-based ingredients offering a 'dry-slip' feel.


Ethylhexyl palmitate is a clear, colorless liquid at room temperature with a slightly fatty odor.
Ethylhexyl Palmitate is insoluble in water but mildly dissolves in oils.
Ethylhexyl Palmitate is a high quality colorless liquid with the added benefit of sustainable manufacturing.


Ethylhexyl Palmitate, also known as octyl palmitate, is a fatty acid ester that comes from 2-ethylhexanol and palmitic acid which is used in cosmetic formulations.
Ethylhexyl palmitate, or octyl palmitate, is the ester of 2-ethylhexyl alcohol (which occurs in essential oils) and palmitic acid (obtained from palm trees).



USES and APPLICATIONS of ETHYLHEXYL PALMITATE:
Ethylhexyl palmitate is used in cosmetic formulations as a solvent, carrying agent, pigment wetting agent, fragrance fixative and emollient.
Ethylhexyl Palmitate's dry-slip skinfeel is similar to some silicone derivatives.
As a solvent, Ethylhexyl Palmitate helps solubilize other ingredients, helping active ingredients more readily penetrate skin.


Ethylhexyl Palmitate is a mixture of a fatty alcohol and palmitic acid that functions in cosmetics products as an emollient (meaning it can soften and smooth skin), texture enhancer, and solvent in amounts from 2-50%, depending on the type of formula and desired aesthetics.
Ethylhexyl Palmitate improves the look of skin, particularly dry skin, by helping reduce moisture loss from its upper layers.


Ethylhexyl Palmitate helps sunscreen active ingredients such as avobenzone and ethylhexyl triazone disperse and remain evenly suspended in a formula.
Ethylhexyl Palmitate is non-occlusive emollient that provides a silky feel in various skin and hair care products.
Ethylhexyl palmitate is commonly used in cosmetic formulations.


Ethylhexyl Palmitate, also known as Octyl Palmitate, is a renewable palm derivative used primarily in cosmetic applications.
Ethylhexyl Palmitate has similar properties to Isopropyl Palmitate, and it can be used in place of Silicone in some applications.
Ethylhexyl Palmitate is used in cosmetic formulations as a solvent, carrying agent, wetting agent, emollient, and used mostly in the formulation of, eye/skin makeup, lipstick and skin care products.


Ethylhexyl Palmitate also widely used in metal working fluids, textile auxiliaries and lube & grease.
Ethylhexyl Palmitate, also known as octyl palmitate, is a fatty acid ester that comes from 2-ethylhexanol and palmitic acid which is used in cosmetic formulations.


Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.
Ethylhexyl Palmitate is a non-occlusive emollient with medium-spreading properties.


In addition, Ethylhexyl palmitate may be used as a carrying agent and solvent for other ingredients, a fixative for fragrance, and a pigment-wetting agent in decorative cosmetics.
Ethylhexyl Palmitate is used in skin, hair, and makeup products at a typical use level of 5-50 %.


Ethylhexil Palmitate (also known as Octyl Palmitate) is derived by esterification from Coconut oil and Palm oil and is frequently used as a vegetable-derived alternative to oil-based silicones.
Ethylhexyl Palmitate gives a dry touch to emulsions, increases their spreadability and improves their texture.


Ethylhexyl Palmitate is a fantastic non-occlusive emollient and skin conditioner, leaving the skin soft and smooth.
Ethylhexyl Palmitate is also used as a solvent, carrying agent and fragrance fixative.
As a pigment-wetting agent, Ethylhexyl Palmitate works well with zinc oxide and titanium dioxide in sun creams or in makeup preparations.


Ethylhexyl Palmitate is used Sun creams, body lotions, face creams, serums, makeup, makeup removers, homemade fragrances.
Ethylhexyl Palmitate is a specialty emollient ester.
Ethylhexyl Palmitate acts as a superior emollient, carrying agent, pigment wetting agent, and solvent derived from palm oil.


Ethylhexyl Palmitate is a great replacement for mineral oil.
Ethylhexyl Palmitate is suitable for use in lotions, creams, sunscreens, hair care, and lip care.
Ethylhexyl Palmitate is used for external use only.


Ethylhexyl Palmitate is used Color cosmetics, pressed powders, skin care product, sun care products.
Ethylhexyl Palmitate helps adjust consistency in skin-care products.
Ethylhexyl palmitate is a mixture of a fatty alcohol and palmitic acid that functions in cosmetics products as an emollient (meaning it can soften and smooth skin), texture enhancer, and solvent in amounts from 2–50%, depending on the type of formula and desired aesthetics.


Ethylhexyl Palmitate improves the look of skin, particularly dry skin, by helping reduce moisture loss from its upper layers.
As a solvent, Ethylhexyl Palmitate helps solubilize other ingredients, helping active ingredients more readily penetrate skin.
Ethylhexyl Palmitate helps sunscreen active ingredients such as avobenzone and ethylhexyl triazone disperse and remain evenly suspended in a formula.


Ethylhexyl palmitate has a feel like some silicones and silicone derivatives, making it an alternative to those ingredients in certain formulations.
There’s no research indicating Ethylhexyl Palmitate, which may be synthetic, plant-, or animal-derived, is a problem for skin.
Ethylhexyl palmitate is an ingredient that is used to improve the texture, feel, and the scent of skincare and cosmetic products.


Ethylhexyl Palmitate functions as an emollient, solvent, and fragrance fixative.
In cosmetics and skincare products, ethylhexyl palmitate functions as an emollient, solvent, and fragrance fixative.
Cosmetic formulations of Ethylhexyl Palmitate: emolient, fragrance ingredient, skin conditioning agent.


Industrial uses of Ethylhexyl Palmitate: washing and cleaning products manufacturer, polymers, adhesives and sealants, textile treatment products and dyes, lubricants and greases.
Ethylhexyl Palmitate is also an emollient used in skin care products.


Ethylhexyl Palmitate is capable of enhancing perfume retention in products.
Ethylhexyl Palmitate is widely used as a Re-Fatting agent.
Ethylhexyl Palmitate is considered a technology used in cosmetic ingredients.


Ethylhexyl Palmitate functions like Conditioners and Emollients, Emulsifiers, Solubilizers, and Dispersants.
Ethylhexyl Palmitate is beneficial for long-lasting fragrance release.
Ethylhexyl Palmitate is prominently used in personal care products, beauty care products, and skincare products.


Ethylhexyl Palmitate is recommended for the skin to apply in the form of body creams and lotions.
And in Personal care products, Ethylhexyl Palmitateis used in creams and lotions.
Ethylhexyl Palmitate is used excellent moisturiser with low comedogenicity.


Ethylhexyl Palmitate has branched chain, light non-greasy oil.
Ethylhexyl Palmitate is used in facial and body products including sunscreens.
Ethylhexyl Palmitate is used good mineral oil alternative.


Ethylhexyl Palmitate is used non-oily feel; low congealing point; low viscosity; hydrolysis and oxidation stability.
Ethylhexyl palmitate is used in cosmetic formulations as a solvent, carrying agent, pigment wetting agent, fragrance fixative and emollient.
Ethylhexyl Palmitate is a skin conditioning agent, an emollient and perfuming.


Ethylhexyl Palmitate can be used in a great range of products including lipstick, foundation, eye shadow, sunscreens, hand creams, deodorants, styling gel/lotions, beard care, fragrance for men, diaper cream, body art.
EHP with the chemical name Ethyl Hexyl Palmitate is a wetting agent used for powders in makeup formulations.


-Cosmetic Uses: perfuming agents
skin conditioning - emollient


-Skin care:
Ethylhexyl Palmitate softens and smoothens the skin.
Ethylhexyl Palmitate reduces moisture loss from the upper layers and improves the look of the skin.
As a solvent, Ethylhexyl Palmitate helps solubilize other ingredients, helping active ingredients more readily penetrate into the skin.
Ethylhexyl Palmitate helps active ingredients such as avobenzone and ethylhexyl triazone, commonly found in sunscreen, disperse and remain evenly suspended in a formula


-Hair care:
Ethylhexyl Palmitate works as a medium-spreading emollient and gives the hair a silky appearance
-Cosmetics
Ethylhexyl Palmitate works as a Solvent, Carrying Agent, Pigment Wetting Agent, Fragrance Fixative and Emollient in Cosmetics



USE AND BENEFITS OF ETHYLHEXYL PALMITATE:
Apart from being a natural option for solvent in any preparation, Ethylhexyl Palmitate can also be used to replace silicone.
Ethylhexyl Palmitate has a very light feel on the skin and is non-tacky also.

Ethylhexyl Palmitate forms a thin film over the skin or hair, and it does not let skin lose its inherent moisture, which otherwise can be lost in the process of exposure to the harsh environment, such as wind, sunlight or pollutants.
Silicones have a “dry-slip” feel on the skin, meaning moisturized nongreasy skin, the Ethylhexyl Palmitate also provides a similar effect.

That’s the reason Ethylhexyl Palmitate is an ideal choice as a solvent as a carrying agent and fragrance fixative.
Pigments or colorants even dispersion is very much significant in case of any cosmetic preparation, it should deliver uniform quality from the first to last use, at this point Ethylhexyl Palmitate is used to wet pigments and produce uniform dispersion.
Ethylhexyl Palmitate is used in skincare products, sun pre/post care products, color cosmetics, and pressed powders.



BENEFITS OF ETHYLHEXYL PALMITATE:
*Non-occlusive emollient that provides a silky feel in various skin and hair care products
*Medium spreading
*Can replace mineral oil in formulations



CHEMICAL PROPERTIES OF ETHYLHEXYL PALMITATE:
Ethylhexyl palmitate is a colorless, odorless liquid derived from palm oil that’s used as a skin conditioning emollient and to give products their slip.
Ethylhexyl Palmitate's similar in texture and sometimes used as an alternative to silicone.
Ethylhexyl palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid.
2-ethylhexyl alcohol can be found in natural plant fragrances and also synthetically produced.
Palmitic acid is the most common saturated fatty acid found in animals, plants and microorganisms, and is a major component of palm oil.



WHAT DOES ETHYLHEXYL PALMITATE DO IN A FORMULATION?
*Emollient
*Perfuming
*Solvent



FUNCTIONS OF ETHYLHEXYL PALMITATE:
*Emollient
*Carrier Solvent
*Fixative Pigment
*wetting agent



ETHYLHEXYL PALMITATE:
*A derivative of palm oil lipid and is an ultra mild, skin smoothing ester
*Used in cosmetic formulations as a solvent, carrying agent, pigment wetting agent, fragrance fixative and emollient
*Ethylhexyl palmitate is a derivative of palm oil often used as an organic replacement to silicone.
*Ethylhexyl Palmitate has a 'dry-slip' feel that is very similar to silicone's texture.
*Ethylhexyl Palmitate is found in many skin care products as an ingredient used to adjust the consistency.



FUNCTIONS OF ETHYLHEXYL PALMITATE:
*Emollient:
Ethylhexyl Palmitate softens and softens the skin
*Fragrant agent:
Ethylhexyl Palmitate is used for perfume and aromatic raw materials



ETHYLHEXYL PALMITATE AT A GLANCE:
*Helps soften and smooth skin
*Reduces moisture loss from skin’s upper layers
*Can help active ingredients more readily penetrate skin
*Is used as an alternative to silicone in some skin care products



WHAT IS ETHYLHEXYL PALMITATE USED FOR?
In addition to being used as an emollient in cosmetics, Ethylhexyl Palmitate is also used as a solvent, carrying agent, pigment-wetting agent, and fragrance fixative.



SAFETY PROFILE OF ETHYLHEXYL PALMITATE:
Ethylhexyl palmitate is not known to pose any health hazards to the skin or the body.
Ethylhexyl Palmitate is considered as safe for use in cosmetics.



ALTERNATIVES OF ETHYLHEXYL PALMITATE:
*COCOCAPRYLATE
*BUTYLENE GLYCOL DICAPRYLATE DICAPRATE



WHAT IS ETHYLHEXYL PALMITATE?
Ethylhexyl Palmitate, also called Octyl Palmitate, is a clear, colorless, practically odorless liquid.
Cetyl Palmitate is a white, crystalline, wax-like substance.
Isopropyl Palmitate is a colorless, almost odorless, liquid.
In cosmetics and personal care products, the Palmitates are used in a wide spectrum of products.



WHY IS ETHYLHEXYL PALMITATE USED IN COSMETICS AND PERSONAL CARE PRODUCTS?
The Palmitate ingredients act as lubricants on the skin’s surface, which gives the skin a soft and smooth appearance.
Isopropyl Palmitate may be used as a binder which is an ingredient added to compounded dry powder mixtures of solids to provide adhesive qualities during and after compression to make tablets or cakes.



SCIENTIFIC FACTS OF ETHYLHEXYL PALMITATE:
The Palmitates are produced using palmitic acid, a naturally occurring fatty acid found in plants and animals, along with smaller amounts of other fatty acids.
Cetyl Palmitate also occurs naturally as a chief constituent of spermaceti (wax from sperm whale oil) and can be found in staghorn coral.



MOISTURE OF ETHYLHEXYL PALMITATE:
As an emollient, Ethylhexyl Palmitate helps to keep the skin moist and supple by reducing water loss from the top layers of the skin.
Emollients also act as lubricants by reducing friction when anything rubs against the skin.
Ethylhexyl palmitate is considered to be a non-occlusive emollient, which means it does not form a film on the surface of the skin.

Ethylhexyl Palmitate is often used as an organic replacement to silicones in a cosmetic formulation because it provides a dry-slip, silky feel that is very similar to how a silicone would feel.
While all skin types can benefit from emollients like ethylhexyl palmitate, emollients are very beneficial for those who have dry, rough, and/or flaky skin.

Emollients can treat these symptoms, leaving the skin looking and feeling soft and smooth.
In addition, emollients may be suitable for those that suffer from conditions such as eczema, psoriasis, or other inflammatory skin conditions.



SOLVENT:
Ethylhexyl palmitate functions as a solvent by helping other ingredients dissolve.
Solvents can also increase the efficacy of active ingredients in a formulation by enhancing their absorption through the skin.



APPEARANCE OF ETHYLHEXYL PALMITATE:
Another function of ethylhexyl palmitate in cosmetics is as a pigment wetting agent.
Wetting agents work by reducing the interfacial tension between two different types of ingredients in a cosmetic formulation.
Wetting agents are useful in makeup as they improve the pigment or color distribution in the formulation.
Think about even eyeshadow or foundation pigment.



FRAGRANCE OF ETHYLHEXYL PALMITATE:
Lastly, Ethylhexyl Palmitate functions as a fragrance fixative in cosmetics and skincare products.
A fixative helps to equalize the volatile fragrance components making them last longer and remain more stable on the skin.



PHYSICAL and CHEMICAL PROPERTIES of ETHYLHEXYL PALMITATE:
Chemical formula: C24H48O2
Molar mass: 368.646 g·mol−1
Boiling Point: 398.93°C
Melting Point: 2°C
Solubility: Soluble in chloroform and hexanes
Appearance: colorless liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 399.00 to 402.00 °C. @ 760.00 mm Hg (est)
Flash Point: 399.00 °F. TCC ( 203.70 °C. ) (est)
logP (o/w): 10.819 (est)
Soluble in: alcohol, water, 4.127e-006 mg/L @ 25 °C (est)
Molecular Weight: 368.6 g/mol
XLogP3-AA: 10.6
Hydrogen Bond Donor Count: 0

Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 21
Exact Mass: 368.365430770 g/mol
Monoisotopic Mass: 368.365430770 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Count: 26
Formal Charge: 0
Complexity: 288
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Physical state: liquid
Colour: various
Odour: characteristic
pH (value): not determined
Melting point/freezing point: Initial boiling point and boiling range: not determined
Flash point: 210 °C at 1,013 hPa
Evaporation rate: not determined
Flammability (solid, gas): not relevant, (fluid)
Explosive limits: not determined
Vapour pressure: 0 Pa at 25 °C
Density: 0.859 g /cm³ at 20 °C
Vapour density this information is not available
Solubility(ies): Water solubility 0 mg/l at 25 °C
Partition coefficient: n-octanol/water (log KOW) 10.61
Soil: organic carbon/water (log KOC) 6.728
Auto-ignition temperature: not determined

Viscosity
Kinematic viscosity: 2.8 mm²/s at 100 °C
Explosive properties: none
Oxidising properties: none
Other information: Solvent content 100 %
Melting point: 2 °C
Boiling point: 398.93°C (rough estimate)
Density: 0.8789 (rough estimate)
refractive index: 1.4463 (estimate)
storage temp.: Refrigerator
solubility: Chloroform (Slightly), Hexanes (Slightly)
form: Solid
color: Off-White
Specific Gravity: 0.86
Water Solubility: 4.13ng/L at 25℃
LogP: 10.819 (est)



FIRST AID MEASURES of ETHYLHEXYL PALMITATE:
-Description of first aid measures:
*General notes:
Keep affected person warm, still and covered.
Take off immediately all contaminated clothing.
Never give anything by mouth.
*Following inhalation:
Provide fresh air.
*Following skin contact:
Wash with plenty of soap and water.
*Following eye contact:
Remove contact lenses, if present and easy to do.
Continue rinsing.
Irrigate copiously with clean, fresh water for at least 10 minutes, holding the eyelids apart.
*Following ingestion:
Rinse mouth with water (only if the person is conscious).
Do NOT induce vomiting.
-Indication of any immediate medical attention and special treatment needed:
none



ACCIDENTAL RELEASE MEASURES of ETHYLHEXYL PALMITATE:
-Personal precautions, protective equipment and emergency procedures:
*For non-emergency personnel:
Remove persons to safety.
-Environmental precautions:
Keep away from drains, surface and ground water.
Retain contaminated washing water and dispose of it.
-Methods and material for containment and cleaning up:
*Advice on how to contain a spill:
Covering of drains
*Advice on how to clean up a spill:
Wipe up with absorbent material (e.g. cloth, fleece).
*Collect spillage:
sawdust, kieselgur (diatomite), sand, universal binder
-Appropriate containment techniques:
Use of adsorbent materials.
-Other information relating to spills and releases:
Place in appropriate containers for disposal.
Ventilate affected area.



FIRE FIGHTING MEASURES of ETHYLHEXYL PALMITATE:
-Extinguishing media:
*Suitable extinguishing media:
Water spray
BC-powder
Carbon dioxide (CO2)



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLHEXYL PALMITATE:
-Exposure controls:
--Appropriate engineering controls:
General ventilation.
-Individual protection measures (personal protective equipment):
*Eye/face protection:
Wear eye/face protection.
*Hand protection:
Wear suitable gloves.
Chemical protection gloves are suitable, which are tested according to EN 374.
-Other protection measures:
Wash hands thoroughly after handling.
-Environmental exposure controls:
Use appropriate container to avoid environmental contamination.
Keep away from drains, surface and ground water.



HANDLING and STORAGE of ETHYLHEXYL PALMITATE:
-Precautions for safe handling:
*Recommendations:
Use local and general ventilation.
Use only in well-ventilated areas.
-Advice on general occupational hygiene:
Wash hands after use.
Do not eat, drink and smoke in work areas.
Remove contaminated clothing and protective equipment before entering eating areas.
Never keep food or drink in the vicinity of chemicals.
Never place chemicals in containers that are normally used for food or drink.
-Conditions for safe storage, including any incompatibilities:
*Packaging compatibilities:
Only packagings which are approved may be used.



STABILITY and REACTIVITY of ETHYLHEXYL PALMITATE:
-Chemical stability:
The material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.
-Possibility of hazardous reactions:
No known hazardous reactions.
-Conditions to avoid:
There are no specific conditions known which have to be avoided.



SYNONYMS:
Hexadecanoic acid 2-ethylhexyl ester
Octyl palmitate
2-ETHYLHEXYL PALMITATE
29806-73-3
2-Ethylhexyl hexadecanoate
Elfacos EHP
Hexadecanoic acid, 2-ethylhexyl ester
Ceraphyl 368
Wickenol 155
Palmitic acid, 2-ethylhexyl ester
EINECS 249-862-1
AI3-31580
UNII-2865993309
EC 249-862-1
2- ethylhexyl palmitate
2 - ethylhexyl palmitate
SCHEMBL15529
DTXSID3027958
Palmitic acid 2-ethylhexyl ester
Palmitic acid-2-ethylhexyl ester
(2-ETHYLHEXYL) PALMITATE
ETHYLHEXYL PALMITATE [INCI]
(+/-)-ETHYLHEXYL PALMITATE
ETHYLHEXYL PALMITATE [VANDF]
MFCD00072255
ETHYLHEXYL PALMITATE [WHO-DD]
AKOS016010384
ETHYLHEXYL PALMITATE, (+/-)-
AS-15135
LS-101204
CS-0063978
E1435
FT-0709066
D97727
EN300-1719134
A876381
J-017652
Hexadecanoic acid, 2-ethylhexyl ester (Palmitic acid, 2-ethylhexyl ester)
Hexadecanoic acid, 2-ethylhexyl esterOctyl palmitate
2-ETHYLHEXYL PALMITATE
OCTYL PALMITATE
ETHYL HEXYL PALMITATE
HEXADECANOIC ACID OCTYL ESTER
wickenol155
ceraphyl368
EVERNOL EHP
Elfacos EHP
OCTYL PALMITAE
octyl Plmitate
2-Ethylhexyl Hexadecanoate
Palmitic Acid 2-Ethylhexyl Ester
Hexadecanoic Acid 2-Ethylhexyl Ester
ISOOCTYL PALMITATE
Isooctyl hexadecanoate
Palmitic acid, 6-methylheptyl ester
Palmitic acid 2-ethylhexyl ester
6-methylheptyl hexadecanoate
Palmitic acid isooctyl
2-EHP
Isooctyl palmitate



ETHYLHEXYL PALMITATE
ETHYLHEXYL PALMITATE ETHYLHEXYL PALMITATE Ethylhexyl Palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid. It is an alternate to silicone-based ingredients offering a ‘dry-slip' feel. It helps adjust consistency in skin-care products. ETHYLHEXYL PALMITATE is classified as : Emollient Perfuming CAS Number 29806-73-3 EINECS/ELINCS No: 249-862-1 COSING REF No: 33890 Chem/IUPAC Name: Hexadecanoic acid, 2-ethylhexyl ester; Octyl palmitate Ethylhexyl Palmitate What Is Ethylhexyl Palmitate? Ethylhexyl Palmitate, also called Octyl Palmitate, is a clear, colorless, practically odorless liquid. Cetyl Palmitate is a white, crystalline, wax-like substance. Isopropyl Palmitate is a colorless, almost odorless, liquid. In cosmetics and personal care products, the Palmitates are used in a wide spectrum of products. Why is Ethylhexyl Palmitate used in cosmetics and personal care products? The Palmitate ingredients act as lubricants on the skin's surface, which gives the skin a soft and smooth appearance. Isopropyl Palmitate may be used as a binder which is an ingredient added to compounded dry powder mixtures of solids to provide adhesive qualities during and after compression to make tablets or cakes. Scientific Facts: The Palmitates are produced using palmitic acid, a naturally occurring fatty acid found in plants and animals, along with smaller amounts of other fatty acids. Cetyl Palmitate also occurs naturally as a chief constituent of spermaceti (wax from sperm whale oil) and can be found in staghorn coral. Ethylhexyl palmitate Ethylhexyl palmitate Ethylhexyl palmitate.png Names IUPAC name Hexadecanoic acid 2-ethylhexyl ester Other names Octyl palmitate Identifiers CAS Number 29806-73-3 check 3D model (JSmol) Interactive image ChemSpider 8649628 check ECHA InfoCard 100.045.314 PubChem CID 10474217 UNII 2865993309 check CompTox Dashboard (EPA) DTXSID3027958 Properties Chemical formula C24H48O2 Molar mass 368.646 g·mol−1 Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Ethylhexyl palmitate, or octyl palmitate, is the fatty acid ester derived from 2-ethylhexanol and palmitic acid. Ethylhexyl palmitate is commonly used in cosmetic formulations. Chemical structure Ethylhexyl palmitate is a branched saturated fatty ester derived from ethylhexyl alcohol and palmitic acid. Physical properties Ethylhexyl palmitate is a clear, colorless liquid at room temperature with a slightly fatty odor. Palmitic acid and 2-ethylhexanol are reacted in the presence of an acid catalyst to make the ester. Uses Ethylhexyl palmitate is used in cosmetic formulations as a solvent, carrying agent, pigment wetting agent, fragrance fixative and emollient. Its dry-slip skinfeel is similar to some silicone derivatives. ETHYLHEXYL PALMITATE Benefits of ethylhexyl palmitate: Non-occlusive emollient that provides a silky feel in various skin and hair care products Medium spreading Can replace mineral oil in formulations Use: Can be added to formulas as is, add to oil phase, use level 2-50%. Storage: Stable when kept in a closed container at a cool & dry place. For external use only. Applications: Color cosmetics, pressed powders, skin care product, sun care products. Raw material source: 2-ethylhexanol and palmitic acid Manufacture: Esterification of palmitic acid and 2-ethylhexanol to form an ester Animal Testing: Not animal tested GMO: Not tested for GMOs but very unlikely to contain GMOs Vegan: Does not contain animal-derived components. What Is It? Ethylhexyl Palmitate, also called Octyl Palmitate, is a clear, colorless, practically odorless liquid. Cetyl Palmitate is a white, crystalline, wax-like substance. Isopropyl Palmitate is a colorless, almost odorless, liquid. In cosmetics and personal care products, the Palmitates are used in a wide spectrum of products. Why is it used in cosmetics and personal care products? The Palmitate ingredients act as lubricants on the skin's surface, which gives the skin a soft and smooth appearance. Isopropyl Palmitate may be used as a binder which is an ingredient added to compounded dry powder mixtures of solids to provide adhesive qualities during and after compression to make tablets or cakes. Scientific Facts: The Palmitates are produced using palmitic acid, a naturally occurring fatty acid found in plants and animals, along with smaller amounts of other fatty acids. Cetyl Palmitate also occurs naturally as a chief constituent of spermaceti (wax from sperm whale oil) and can be found in staghorn coral. Is Ethylhexyl Palmitate Comedogenic? Ethylhexyl Palmitate is highly comedogenic. It means that if this ingredient is present in any product, it is very likely to cause pimples on acne prone skin. Even if your skin does not break out easily, you need be careful with products containing this ingredient. Ethylhexyl palmitate, or octyl palmitate, is the fatty acid ester derived from 2-ethylhexanol and palmitic acid. Ethylhexyl palmitate is commonly used in cosmetic formulations. Ethylhexyl palmitate is a branched saturated fatty ester derived from ethylhexyl alcohol and palmitic acid. Ethylhexyl palmitate is used in cosmetic formulations as a solvent, carrying agent, pigment wetting agent, fragrance fixative and emollient. Its dry-slip skinfeel is similar to some silicone derivatives. Description: Ester of 2-ethylhexanol and palmitic acid. Synonym: Octyl Palmitate. Saponification value 130 - 160. Clear amber liquid. Insoluble in water, miscible in oils. ven if a single ingredient such as Ethylhexyl Palmitate in a skincare or cosmetic / makeup product is comedogenic, that becomes its weakest link, rendering the product as a whole comedogenic. Manually checking an ingredient list for the presence of comedogenic ingredients can be tiresome. A free online tool anyone can use to find out instantly if a skincare or makeup product contains comedogenic or acnegenic ingredients. With Skingredients, you can also check if a single ingredient like Ethylhexyl Palmitate is comedogenic. There is also a smartphone version of Acne Mantra Skingredients. Get Skingredients on your Android smartphone. Depending on your Acne Prone Skin Type (1, 2 or 3), an ingredient may block your pores more or less depending on its comedogenicity. You need to be aware of these acne causing ingredients that may cause or aggravate acne. Is Ethylhexyl Palmitate Comedogenic? Ethylhexyl Palmitate is highly comedogenic. It means that if this ingredient is present in any product, it is very likely to cause pimples on acne prone skin. Even if your skin does not break out easily, you need be careful with products containing this ingredient. Comedogenic ingredients are pore-clogging and can cause breakouts. Even if a single ingredient such as Ethylhexyl Palmitate in a skincare or cosmetic / makeup product is comedogenic, that becomes its weakest link, rendering the product as a whole comedogenic. Manually checking an ingredient list for the presence of comedogenic ingredients can be tiresome. Enter Acne Mantra Skingredients, a free online tool anyone can use to find out instantly if a skincare or makeup product contains comedogenic or acnegenic ingredients. With Skingredients, you can also check if a single ingredient like Ethylhexyl Palmitate is comedogenic. Depending on your Acne Prone Skin Type (1, 2 or 3), an ingredient may block your pores more or less depending on its comedogenicity. You need to be aware of these acne causing ingredients that may cause or aggravate acne. Many comedogenic cosmetic ingredient lists rate comedogenic ingredients on a scale of 1-5, with 5 being the most comedogenic. In real life, comedogenicity does not vary at such a fine scale. You are better off using a more practical scale such as non-comedogenic, mildly comedogenic and highly comedogenic. Ethylhexyl Palmitate is not known to be irritating to the skin. Skin irritants may cause acne even if they are not pore-clogging. This is because they irritate the skin causing it to produce more sebum which may result in acne. Ethylhexyl Palmitate is mainly used as an emollient, perfuming agent in cosmetic products. Ethylhexyl palmitate is an ingredient that is used to improve the texture, feel, and the scent of skincare and cosmetic products. It functions as an emollient, solvent, and fragrance fixative. Ethylhexyl palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid. 2-ethylhexyl alcohol can be found in natural plant fragrances and also synthetically produced. Palmitic acid is the most common saturated fatty acid found in animals, plants and microorganisms, and is a major component of palm oil. Ethylhexyl palmitate is a clear, colorless liquid at room temperature with a slightly fatty odor. It is insoluble in water but mildly dissolves in oils. Why Is Ethylhexyl Palmitate Used? In cosmetics and skincare products, ethylhexyl palmitate functions as an emollient, solvent, and fragrance fixative. Moisture As an emollient, ethylhexyl palmitate helps to keep the skin moist and supple by reducing water loss from the top layers of the skin. Emollients also act as lubricants by reducing friction when anything rubs against the skin. Ethylhexyl palmitate is considered to be a non-occlusive emollient, which means it does not form a film on the surface of the skin. It is often used as an organic replacement to silicones in a cosmetic formulation because it provides a dry-slip, silky feel that is very similar to how a silicone would feel. While all skin types can benefit from emollients like ethylhexyl palmitate, emollients are very beneficial for those who have dry, rough, and/or flaky skin. Emollients can treat these symptoms, leaving the skin looking and feeling soft and smooth. In addition, emollients may be suitable for those that suffer from conditions such as eczema, psoriasis, or other inflammatory skin conditions. Solvent Ethylhexyl palmitate functions as a solvent by helping other ingredients dissolve. Solvents can also increase the efficacy of active ingredients in a formulation by enhancing their absorption through the skin. Appearance Another function of ethylhexyl palmitate in cosmetics is as a pigment wetting agent. Wetting agents work by reducing the interfacial tension between two different types of ingredients in a cosmetic formulation. Wetting agents are useful in makeup as they improve the pigment or color distribution in the formulation. Think about even eyeshadow or foundation pigment. Fragrance Lastly, ethylhexyl palmitate functions as a fragrance fixative in cosmetics and skincare products. A fixative helps to equalize the volatile fragrance components making them last longer and remain more stable on the skin. Is Ethylhexyl Palmitate Safe? The safety of ethylhexyl palmitate and other alkyl esters has been assessed by the Cosmetic Ingredient Review Expert Panel, a group that evaluates the safety of skincare and cosmetic ingredients. In their findings, the Expert Panel was able to determine that ethylhexyl palmitate doesn't show any evidence of toxicity or irritation. It does produce some very mild eye irritation in higher concentrations, usually outside the concentrations used in skincare and cosmetic products. The Expert Panel concluded that ethylhexyl palmitate and other alkyl esters were safe as cosmetic ingredients. Palmitic acid and 2-Ethylhexanol are reacted in the presence of an acid catalyst to make 2-Ethylhexyl palmitate (CAS NO.16958-85-3). It also can be synthesized by using aminosulfonic acid as catalyst under the condition of reduced pres- sure. Instead of aminosulfonic acid, the enzyme can also be used as a catalyst such as the lipase from Candida sp. 99-125. After it is immobilized on surfactant modified cotton membrane, it can be used to prepare the 2-Ethylhexyl palmitate . ethylhexyl palmitate Rating: GOOD Categories: Emollients, Texture Enhancer Mixture of a fatty alcohol and palmitic acid that functions as an emollient and texture enhancer. There’s no research indicating this ingredient, which may be synthetic, plant-, or animal-derived, is a problem for skin. Ethylhexyl Palmitate Why Is Ethylhexyl Palmitate Used In Skincare? Ethylhexyl palmitate is an ingredient that is used to improve the texture, feel, and the scent of skincare and cosmetic products. It functions as an emollient, solvent, and fragrance fixative. Ethylhexyl palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid. 2-ethylhexyl alcohol can be found in natural plant fragrances and also synthetically produced. Palmitic acid is the most common saturated fatty acid found in animals, plants and microorganisms, and is a major component of palm oil. Ethylhexyl palmitate is a clear, colorless liquid at room temperature with a slightly fatty odor. It is insoluble in water but mildly dissolves in oils. Ethylhexyl palmitate THE GOOD:As an emollient, ethylhexyl palmitate can help reduce the appearance of dry flaky skin. Ethylhexyl palmitate is also used to improve the texture and sensory feel of formulations. THE NOT SO GOOD:Can produce eye irritation in high concentrations. However, those concentrations are not in the scope of skincare products. WHO IS IT FOR?All skin types except those that have an identified allergy to it. SYNERGETIC INGREDIENTS:Works well with most ingredients KEEP AN EYE ON:Nothing to keep an eye on here. Why Is Ethylhexyl Palmitate Used? In cosmetics and skincare products, ethylhexyl palmitate functions as an emollient, solvent, and fragrance fixative. Moisture As an emollient, ethylhexyl palmitate helps to keep the skin moist and supple by reducing water loss from the top layers of the skin. Emollients also act as lubricants by reducing friction when anything rubs against the skin. Ethylhexyl palmitate is considered to be a non-occlusive emollient, which means it does not form a film on the surface of the skin. It is often used as an organic replacement to silicones in a cosmetic formulation because it provides a dry-slip, silky feel that is very similar to how a silicone would feel. While all skin types can benefit from emollients like ethylhexyl palmitate, emollients are very beneficial for those who have dry, rough, and/or flaky skin. Emollients can treat these symptoms, leaving the skin looking and feeling soft and smooth. In addition, emollients may be suitable for those that suffer from conditions such as eczema, psoriasis, or other inflammatory skin conditions. Solvent Ethylhexyl palmitate functions as a solvent by helping other ingredients dissolve. Solvents can also increase the efficacy of active ingredients in a formulation by enhancing their absorption through the skin. Appearance Another function of ethylhexyl palmitate in cosmetics is as a pigment wetting agent. Wetting agents work by reducing the interfacial tension between two different types of ingredients in a cosmetic formulation. Wetting agents are useful in makeup as they improve the pigment or color distribution in the formulation. Think about even eyeshadow or foundation pigment. Fragrance Lastly, ethylhexyl palmitate functions as a fragrance fixative in cosmetics and skincare products. A fixative helps to equalize the volatile fragrance components making them last longer and remain more stable on the skin. Is Ethylhexyl Palmitate Safe? The safety of ethylhexyl palmitate and other alkyl esters has been assessed by the Cosmetic Ingredient Review Expert Panel, a group that evaluates the safety of skincare and cosmetic ingredients. In their findings, the Expert Panel was able to determine that ethylhexyl palmitate doesn’t show any evidence of toxicity or irritation. It does produce some very mild eye irritation in higher concentrations, usually outside the concentrations used in skincare and cosmetic products. The Expert Panel concluded that ethylhexyl palmitate and other alkyl esters were safe as cosmetic ingredients.
ETHYLHEXYL PALMITATE ( Palmitate d'octyle) Palmitate d'octyle ( Octyl palmitate)
ETHYLHEXYL PELARGONATE, N° CAS : 59587-44-9. Nom INCI : ETHYLHEXYL PELARGONATE. Nom chimique : 2-Ethylhexyl nonanoate. N° EINECS/ELINCS : 261-819-9. Ses fonctions (INCI), Emollient : Adoucit et assouplit la peau
ETHYLHEXYL PELARGONATE
ETHYLHEXYL POLYHYDROXYSTEARATE, N° CAS : 1423155-00-3. Nom INCI : ETHYLHEXYL POLYHYDROXYSTEARATE. Ses fonctions (INCI). Emollient : Adoucit et assouplit la peau, Agent d'entretien de la peau : Maintient la peau en bon état
ETHYLHEXYL POLYHYDROXYSTEARATE
ETHYLHEXYL SALICYLATE. N° CAS : 118-60-5. Origine(s) : Synthétique. Nom INCI : ETHYLHEXYL SALICYLATE. Nom chimique : 2-Ethylhexyl salicylate. N° EINECS/ELINCS : 204-263-4 La concentration maximale autorisée en cosmétique est la suivante : 5 %.. Ses fonctions (INCI). Absorbant UV : Protège le produit cosmétique contre les effets de la lumière UV. Filtre UV : Permet de filtrer certains rayons UV afin de protéger la peau ou les cheveux des effets nocifs de ces rayons.
ETHYLHEXYL SALICYLATE
ETHYLHEXYL STEARATE, N° CAS : 22047-49-0, Nom INCI : ETHYLHEXYL STEARATE, N° EINECS/ELINCS : 244-754-0. Ses fonctions (INCI): Emollient : Adoucit et assouplit la peau; 22047-49-0 [RN]; 244-754-0 [EINECS]; 2-ethylhexyl octadecanoate; 2-Ethylhexyl stearate; 2-Ethylhexylstearat [German] ; ETHYLHEXYL STEARATE;Octadecanoic acid, 2-ethylhexyl ester [ACD/Index Name] Stéarate de 2-éthylhexyle [French] [22047-49-0] 2-Ethylhexyl stearate, mixture of stearate and palmitate (7:3) 2-Ethylhexyl stearate, mixture of stearate and palmitate (7:3), Technical grade 2-Ethylhexyloctadecanoate 2-ETHYLHEXYLSTEARATE ethyl 4-hydroxycyclohexane-1-carboxylate MFCD00072275 [MDL number] SCHEMBL153398 stearic acid, 2-ethylhexyl ester
ETHYLHEXYL SALICYLATE (OCTISALATE USP)
2-Ethylhexyl salicylate ,WMO;usafdo-11;Sunarome O;USAF do-11;EUSOLEX OS;OCTISALATE;Escalol 587;Uvinul O-18;Sunarome WMO;Dermoblock OS , shuiyangsuanyixinzhi;OCTYL SALICYLATE(OS);2-hydroxy-benzoicaci2-ethylhexylester;Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester;Benzoicacid,2-hydroxy-,2-ethylhexylester;Ethylhexyl salicylate CAS No.118-60-5
ETHYLHEXYL STEARATE
2-Ethylhexyl stearate octadecanoic acid; 2-ethylhexyl ester 2-ethylhexyl octadecanoate cas no: 22047-49-0
ETHYLHEXYL STEARATE
Ethylhexyl stearate is again one member of the groups called stearate esters which are obtained by reacting stearic acid with an alkyl group containing alcohol.
Ethylhexyl stearate is a clear, almost colorless (or slightly yellowish) oily liquid (an ester to be precise) that's used as a medium spreading emollient.
Ethylhexyl stearate gives skin a nice and smooth after-feel and it's very good at reducing oiliness or greasiness coming from other heavier oils in the formula.

CAS Number: 22047-49-0
EC Number: 244-754-0
Molecular Formula: C26H52O2
Molecular Weight: 396.6899

22047-49-0 [RN] 244-754-0 [EINECS] 2-ethylhexyl octadecanoate 2-Ethylhexyl stearate [ACD/IUPAC Name] 2-Ethylhexylstearat [German] [ACD/IUPAC Name] ETHYLHEXYL STEARATE Octadecanoic acid, 2-ethylhexyl ester [ACD/Index Name] Stéarate de 2-éthylhexyle [French] [ACD/IUPAC Name] [22047-49-0] 2-Ethylhexyl stearate, mixture of stearate and palmitate (7:3) 2-Ethylhexyl stearate, mixture of stearate and palmitate (7:3), Technical grade 2-Ethylhexyloctadecanoate 2-ETHYLHEXYLSTEARATE AGN-PC-00L26C CHEMBL3184927 DSSToxCID27178 DSSToxGSID47178 DSSToxRID82175 ethyl 4-hydroxycyclohexane-1-carboxylate MFCD00072275 [MDL number] SCHEMBL153398 stearic acid, 2-ethylhexyl ester Octadecanoic acid, octyl ester [ACD/Index Name] octyl octadecanoate Octyl stearate [ACD/IUPAC Name] Octylstearat [German] [ACD/IUPAC Name] Stéarate d'octyle [French] [ACD/IUPAC Name] Stearic acid, octyl ester 22047-49-0 [RN] 244-754-0 [EINECS] 2-ethylhexyl octadecanoate 2-Ethylhexyl stearate [ACD/IUPAC Name] 2-Ethylhexylstearat [German] [ACD/IUPAC Name], ETHYLHEXYL STEARATE, Octadecanoic acid, 2-ethylhexyl ester [ACD/Index Name], Stéarate de 2-éthylhexyle [French] [ACD/IUPAC Name], [22047-49-0] [RN], 2-Ethylhexyl stearate, mixture of stearate and palmitate (7:3), 2-Ethylhexyloctadecanoate, 2-ETHYLHEXYLSTEARATE, AGN-PC-00L26C, CHEMBL3184927, DSSToxCID27178, DSSToxGSID47178, DSSToxRID82175, ethyl 4-hydroxycyclohexane-1-carboxylate, MFCD00072275 [MDL number], SCHEMBL153398, stearic acid, 2-ethylhexyl ester, 2-Ethylhexyl stearate, 22047-49-0, 2-Ethylhexyl octadecanoate, Ethylhexyl stearate, Cetiol 868, Octadecanoic acid, 2-ethylhexyl ester, EG3PA2K3K5, DTXSID9047178, Stearic acid, 2-ethylhexyl ester, C26H52O2, ethyl hexyl stearate, CRODAMOL OS, TEGOSOFT OS, ETHOX EHS, PELEMOL OS, EXCEPARL EH-S, UNII-EG3PA2K3K5, SCHEMBL153398, ?2-ETHYLHEXYL STEARATE, ESTOL 1545, CHEMBL3184927, DTXCID7027178, OPJWPPVYCOPDCM-UHFFFAOYSA-N, ETHYLHEXYL STEARATE [INCI], Tox21_302619, ETHYLHEXYL STEARATE [WHO-DD], MFCD00072275, AKOS015901877, NCGC00256861-01, CAS-22047-49-0, CS-0152204, FT-0756635, E78095, EC 244-754-0, W-110539, Q27277167, OCTADECANOIC ACID, 2-ETHYLHEXYL ESTER, (+/-)-, 2-Ethylhexyl stearate, mixture of stearate and palmitate (4:6)

Ethylhexyl stearate is commonly used as an emollient to deliver skin-softening properties and a smooth afterfeel.
Ethylhexyl stearate is a medium spreading emollient for all kind of cosmetic applications.

Ethylhexyl stearate or octyl stearate is an ester of stearic acid with octanol.
Ethylhexyl stearate is again one member of the groups called stearate esters which are obtained by reacting stearic acid with an alkyl group containing alcohol.

Stearate esters all have unique properties of oily nature, but low viscosity and lighter feel.
That’s why they are the choice of solvents in makeup related products.

Ethylhexyl stearate is obtained from various animal and plant source.
Ethylhexyl stearate comes as clear to slightly yellowish liquid.

Ethylhexyl stearate, also known as 2-Ethylhexyl stearate or Octyl Stearate, is a renewable palm derivative with a variety of uses in both personal care and cosmetics manufacturing.
Ethylhexyl stearate is a stearate ester with similar properties to Isopropyl Myristate.
As with all stearate personal care esters, the Ethylhexyl stearate manufacturing process entails a reaction between Ethylhexyl stearate and alcohols such as cetyl, butyl, isopropyl or myristyl alcohol.

Ethylhexyl stearate is a fatty acid derived from animal fat.
Ethylhexyl stearate acts as a lubricant that softens the skin and gives Ethylhexyl stearate a smooth appearance.

Ethylhexyl stearate is excellent liquid emollient and thickening agent for cosmetic formulations.
Ethylhexyl stearate provides a soft barrier to the skin to impart moisturization and a smooth feel.

Ethylhexyl stearate is a clear, almost colorless (or slightly yellowish) oily liquid (an ester to be precise) that's used as a medium spreading emollient.
Ethylhexyl stearate gives skin a nice and smooth after-feel and it's very good at reducing oiliness or greasiness coming from other heavier oils in the formula.

Ethylhexyl stearate is used an emollient derived from plant oil that prevents water loss
Ethylhexyl stearate is also known as Octyl Stearate

Ethylhexyl stearate also known as 2-Ethylhexyl Octadecanoate or Octyl stearate is a palm derivative which is renewable in nature and is extensively used in personal care industry.
The stearate esters are prepared by the reaction between Ethylhexyl stearate and alcohol such as isopropyl, ethylhexyl, myistyl alcohol, cetyl, butyl among others.

Ethylhexyl stearate can be obtained form from animal origin as well as vegetable fats.
Ethylhexyl stearate is prepared by the reaction between Ethylhexyl stearate and ethylhexyl alcohol.

Ethylhexyl stearate is a clear ester liquid which is free of suspended matter and is available in colourless liquid form.
Ethylhexyl alcohol possess unique property of low viscosity and oily nature owing to which when applied on skin or lips Ethylhexyl stearate forms an hydrophobic film.
Thereby, softens the skin and imparts smooth appearance.

With rising consumer concern towards personal health, demand for personal care serices and products are witnessing a substantial growth.
Thereby, boosting the market growth of Ethylhexyl stearate is commonly used ester in personal care products.

Ethylhexyl stearate is commonly used as an emollient which prevents the water loss.
Hence, is extensively used as emulsion, bath oils and as solvent in cosmetic products.

Ethylhexyl stearate is widely used in the manufacturing of formulations for skin make up, lipstick, eye liner and other skin care products.
Apart from personal care industry, Ethylhexyl stearate also widely used as an intermediate, lubricating agent and surface active agent.

Owing to these properties ethtylhexyl stearate is commonly used in the manufacturing of metal working fluids.
Also, Ethylhexyl stearate offers good thermal stability and hence finds application in aluminium rolling, also is used in manufacturing of ink additives and paints.
Hence, broad spectrum of application provides an opportunistic platform for the robust growth of Ethylhexyl stearate market over the period of time.

Ethylhexyl stearate is a special emollient ester in cosmetic formulations.
Ethylhexyl stearate is a softening, thickening agent, dispersant and solvent.

Ethylhexyl stearate is often used as a base for skin care agents.
Ethylhexyl stearate is suitable for use in lotions, sunscreens, hair care, lip care, eye care, antiperspirant and bath oils.
Ethylhexyl stearate is oil soluble and supplied as a whitish clear liquid.

Ethylhexyl stearate, also known as 2-Ethylhexyl stearate or Octyl Stearate, is a renewable palm derivative that has a variety of uses in both personal care and cosmetic manufacturing.
Ethylhexyl stearate is a stearate ester with similar properties to Isopropyl Myristat.

As with all stearate personal care esters, the Ethylhexyl stearate manufacturing process causes a reaction between Ethylhexyl stearate and alcohols such as cetyl, butyl, isopropyl or myristyl alcohol.
Ethylhexyl stearate acts as a lubricant that softens the skin and gives Ethylhexyl stearate a smooth appearance.

Ethylhexyl stearate or Octyl stearate, is a date derivative that is renewable in nature and widely used in the personal care industry.
Stearate esters are prepared by the reaction between Ethylhexyl stearate and alcohol such as isopropyl, ethylhexyl, myistyl alcohol, cetyl, butyl, among others.

Ethylhexyl stearate can be obtained from vegetable oils as well as from animal origin.
Ethylhexyl stearate is prepared by the reaction between Ethylhexyl stearate and ethylhexyl alcohol.

Ethylhexyl stearate is a clear ester liquid with no suspended matter and available in colorless liquid form.
Ethylhexyl alcohol has a unique property of low viscosity and oily nature, as Ethylhexyl stearate forms a hydrophobic film when applied to the skin or lips.
Thus, Ethylhexyl stearate softens the skin and gives Ethylhexyl stearate a smooth appearance.

Ethylhexyl stearate is an excellent moisturizer with low comedogenicity and medium spreading properties.
Ethylhexyl stearate gives the skin a soft and smooth appearance while preventing water loss.
Ethylhexyl stearate is very suitable for use in sun screen formulations.

Ethylhexyl stearate is a renewable palm derivative with a variety of uses in both personal care and industrial applications.
Ethylhexyl stearate is used in cosmetic formulations as a solvent, carrying agent, wetting agent, emollient, and used mostly in the formulation of, eye/skin makeup, lipstick and skin care products.
Ethylhexyl stearate also widely used in metal working fluids, textile auxiliaries and lube & grease.

Ethylhexyl stearate is a chemical compound that belongs to the family of esters.
Ethylhexyl stearate is commonly used in various industries, including cosmetics, pharmaceuticals, and plastics.
This paper aims to provide a comprehensive review of Ethylhexyl stearate, including Ethylhexyl stearate method of synthesis or extraction, chemical structure, biological activity, biological effects, applications, future perspectives, and challenges.

Ethylhexyl stearate is a low odor product with resistance to extraction by water, oils and solvents.
Ethylhexyl stearate is the least effective costabilizer on Ethylhexyl stearate range due to Ethylhexyl stearate lower oxirane value but is good at reducing viscosity in plastisols and remains liquid down to -20°C.

Ethylhexyl stearate is used in cosmetics to provide a barrier between skin and the elements, and to soften and smooth the skin.
Ethylhexyl stearate used in cosmetics as a thickening agent and emollient.

Ethylhexyl stearate used as plasticizer for natural rubber and synthetic rubber.
Ethylhexyl stearate used as release agent.

Ethylhexyl stearate used as lubricating agent for process aluminium foil; creates plasticity.
Ethylhexyl stearate used in the pharmaceutical industry and in plastics; oil agent of textile; additive for leather.

Ethylhexyl stearate is a light ester with low viscosity (7-10,5 cSt) and emollient properties.
Ethylhexyl stearate improves the spreadability of preparations, Ethylhexyl stearate easily absorbed and leaves a non-greasy, non-occlusive protective film on the skin, which feels silky and smooth.
Ethylhexyl stearate is ideal on makeup formulations such as lipsticks and mascaras.

Ethylhexyl stearate is an ester of stearic acid and 2-ethylhexanol.
Ethylhexyl stearate is a clear, colorless liquid with a faint odor and a low viscosity.

The chemical formula of Ethylhexyl stearate is C26H52O2, and Ethylhexyl stearate has a molecular weight of 368.64 g/mol.
Ethylhexyl stearate is commonly used in the cosmetic industry as an emollient and a solvent.

As an emollient, Ethylhexyl stearate has a softening and smoothing effect on the skin and hair, making them feel less greasy and more comfortable.
As a solvent, Ethylhexyl stearate can dissolve other ingredients and help them spread more evenly on the skin or hair.
Ethylhexyl stearate is considered safe for use in cosmetics, and Ethylhexyl stearate low toxicity makes Ethylhexyl stearate an attractive ingredient for a variety of personal care products.

Ethylhexyl stearate is also known as Octyl stearate, Ethylhexyl stearate can be used as a lubricant in all kinds of cosmetic products.
Ethylhexyl stearate is an IPM alternative.
Ethylhexyl stearate has a medium-low lubrication feel.

Ethylhexyl stearate can be used in products where oiliness is not desired.
Ethylhexyl stearate will also reduce the oiliness of other oils.

Ethylhexyl stearate is a cream-type cleansing cosmetic compound containing large amount of oil phase and Ethylhexyl stearate manufacturing method.
In cosmetics and personal care products, stearate esters are used most frequently in the formulation of eye makeup, skin makeup, lipstick and skin care products.

Ethylhexyl stearate is used in personal care applications and and in can lubes.
Ethylhexyl stearate is a palm dervied product made from Stearic Acid and 2-Ethylhexanol.

Ethylhexyl stearate can be considered a protector of the skin.
Ethylhexyl stearate is an emollient derived from plant oil.

The lipide prevents water loss and therefore helps the skin to efficiently store moisture.
Ethylhexyl stearate is acts as a good moisturizer and emollient for skin creams, lotions and sunscreen.

Ethylhexyl stearate is a cationic polymerization that is used in the production of polyvinyl chloride.
Ethylhexyl stearate has been shown to be an effective additive for hydrophobic effects, and Ethylhexyl stearate has very high values for surface methodology.

Ethylhexyl stearate is also clinically proven to have skin cell penetration properties and can be used as a carrier agent for other ingredients.
The fatty acid portion of this molecule provides hydroxyl groups, which may help with the function of dimethyl fumarate.
Ethylhexyl stearate also contains a potassium hexafluorophosphate group in Ethylhexyl stearate structure, which can be used as an emulsifier or dispersant.

Ethylhexyl stearate is mainly a skin conditioning ingredient and Ethylhexyl stearate acts primarily as lubricant on the skin's surface, which gives the skin a soft and smooth appearance.
In our products, Ethylhexyl stearate is used as hair conditioner.
Ethylhexyl stearate helps to increase the softness and smoothness of hair, reduce tangles and surface roughness.

Use and Benefits of Ethylhexyl stearate:
Ethylhexyl stearate is also linked to skin’s natural fatty acid content, so Ethylhexyl stearate is ideal for skin preparation.
Moreover, Ethylhexyl stearate imparts the right amount of viscosity to Ethylhexyl stearate, Ethylhexyl stearate acts as a thickening agent as well.

Ethylhexyl stearate also forms a film over the skin, a hydrophobic barrier which does not let the moisture pass through and escape from the skin.
And without any greasy feel, Ethylhexyl stearate moisturizes the skin.

Ethylhexyl stearate also nourishes the skin and provides a protective barrier; moist skin is healthy enough to fight any external inflammation.
After regular application, resultant skin may become softer and smoother.
Ethylhexyl stearate is most frequently used in skincare products, lipstick, skin makeup, and eye makeup.

Ethylhexyl stearate is a surfactant with a wide variety of applications and can be found, for example, as a solvent in lubricants and lubricant additives, surface treatment agents.
The following consumer products may contain Ethylhexyl stearate: fabrics, textiles and leather products, detergents, dishwashing liquids, lubricants, oils (excluding food oils) and others.

Ethylhexyl stearate is often used as an emollient to prevent water loss.
For this reason, Ethylhexyl stearate is widely used as a solvent in emulsions, bath oils and cosmetic products.

Ethylhexyl stearate is widely used in the production of formulations for skin make-up, lipstick, eyeliner and other skin care products.
Besides the personal care industry, Ethylhexyl stearate is also used as an intermediate, lubricant and surfactant oris widely used.

Because of these properties, Ethylhexyl stearate is widely used in the production of metalworking fluids.
Ethylhexyl stearate also offers good thermal stability and therefore finds application in aluminum rolling, Ethylhexyl stearate is also used in the manufacture of ink additives and paints.
Therefore, Ethylhexyl stearate wide range of applications provides an opportunistic platform for the Ethylhexyl stearate market to grow strongly over time.

However, with the increasing demand for organic and natural personal care products, various natural-based ingredients are used in the production of personal care products.
Thus, Ethylhexyl stearate limits the market growth of Ethylhexyl stearate.

Moreover, Ethylhexyl stearate is derived from animal fat, which is hindering the growth of the Ethylhexyl stearate market with the increasing adoption of vegan-based products.
Ethylhexyl stearate also causes mild eye irritation and produces a mild odor, which may affect the adoption of ethyl stearate-based products among consumers.

Usage Areas of Ethylhexyl stearate:
Ethylhexyl stearate is used in cosmetic Softener, Dispersant, Solvent and Thickener.
Ethylhexyl stearate is used in metalworking lubricant.

Ethylhexyl stearate is branched chain softener ester specially developed for personal care and pharmaceutical applications.
Ethylhexyl stearate is non-occlusive with good spreading properties.

Ethylhexyl stearate is excellent super lubricant in detergent systems and soaps.
Ethylhexyl stearate is increases hair shine.
Ethylhexyl stearate is used in bath oils, skin cleansers, shampoos and conditioners.

Cosmetic use:
Ethylhexyl stearate is used in oil-based with low viscosity, high penetration and spreading effect.

Uses at industrial sites:
Ethylhexyl stearate is used in the following products: washing & cleaning products, metal surface treatment products, polymers, textile treatment products and dyes and pH regulators and water treatment products.
Ethylhexyl stearate is used for the manufacture of: textile, leather or fur.
Release to the environment of Ethylhexyl stearate can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid, as processing aid and as an intermediate step in further manufacturing of another substance (use of intermediates).

Industry Uses:
Lubricants and lubricant additives
Plating agents and surface treating agents
Solvents (which become part of product formulation or mixture)
Surface active agents
Emulsifier
Hydraulic fluids
Intermediate
Lubricants and lubricant additives
Lubricating agent
Other
Solubility enhancer
Surface modifier
Surfactant (surface active agent)

Consumer Uses:
Ethylhexyl stearate is used in the following products: washing & cleaning products, adhesives and sealants, lubricants and greases, polymers, textile treatment products and dyes, plant protection products, polishes and waxes and fertilisers.
Release to the environment of Ethylhexyl stearate can occur from industrial use: in the production of articles and in processing aids at industrial sites.
Other release to the environment of Ethylhexyl stearate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Other consumer Uses:
Fabric, textile, and leather products not covered elsewhere
Laundry and dishwashing products
Lubricants and greases
Non-TSCA use
Personal care products
Emulsifier
Hydraulic fluids
Intermediate
Lubricants and lubricant additives
Lubricating agent
Other
Solubility enhancer
Surfactant (surface active agent)

Applications of Ethylhexyl stearate:
Ethylhexyl stearate acts as a good moisturizer and emollient in personal care formulations like skin creams, lotions and sunscreens.
Ethylhexyl stearate is also finds use in color cosmetics like eyebrow pencil, concealer, lipstick etc.
Ethylhexyl stearate is used as an oil component for bath oils, bath emulsions, and as a solvent for active substances in cosmetics.

Ethylhexyl stearate is a variety of resin processing of the lubricant, non-toxic, with water resistance and good thermal stability.
Mainly used for PVC transparent soft and hard extrusion, injection molding, calendering products, the amount of 0.5-1 copies.

Ethylhexyl stearate of the modified vinyl chloride - vinyl acetate copolymer, polystyrene, nitrile rubber and other processing performance is also very effective.
Ethylhexyl stearate can also be used as a lubricant for fabrics, waterproofing agents, lubricants additives, cosmetics base material and so on.

Ethylhexyl stearate is a specialty emollient ester.
Ethylhexyl stearate is a superior emollient, thickening agent, dispersant, and solvent.

Ethylhexyl stearate properties allow use as a cleaner or diluent for lipophilic systems; cosmetic emollient and dispersant; plastic additive as external lubricant; industrial lubricant or separator; substitution of mineral, vegetable and selected silicone oils; and pigment binding and dispersing coagent.

Categories: Thickeners / Emulsifiers, Texture Enhancer, Softeners
Ethylhexyl stearate is often used as an emollient for Ethylhexyl stearate skin softening properties and smooth feel.

Ethylhexyl stearate is often used as the base for skin conditioning agents.
Suitable for use in lotions, sunscreens, hair care, lip care, eye care, antiperspirants, and bath oils.

Ethylhexyl stearates serve as intermediates, surface active agents and lubricants/lubricant additives.

Ethylhexyl stearate is functions include the following.
CASE: Paint and Ink Additive
Lube and Grease: Oil Base Fluid
Metal Working Fluids: Lubricant with Excellent Adhesion to Metals and Good Thermal Stability. Also Used in Aluminum Rolling
Plastics: Lubricant
Rubber: Processing Agent
Textiles: Oiling Agent
Personal Care: Thickening Agent, Skin Conditioning Agent and Emollient in Skin Care Products
Cosmetics: Used as a Base, a Thickening Agent, a Pigment Wetting Agent, a Dispersant, a Solvent and an Emollient in Skin and Eye Make-Up and in Lipstick.
Personal care products/cosmetics using Ethylhexyl stearate: Lipstick, eye makeup, skin care and makeup products, moisturizers, anti-wrinkle creams and lotions, anti-aging products, hair conditioners and styling products, baby lotions and eye shadow

Industry Based Ethylhexyl stearate Applications:
Personal care
Textile
Chemicals

Applications of Ethylhexyl stearate based on functionality:
Lubrication
Processing
Darkening
Distributor

Other Applications:
After sun
Baby Care and Cleaning
Body care
Color Care
Facial Facial
Personal Cleaner
Care Wipes
Self Tanning
Sun protection
Bath, Shower & Soaps
Eye Colour
Face / Neck Skin Care
Face Colour
Facial Cleansers
Hair Conditioners - Rinse off
Lip Colour
Shampoos
Sun Protection
Tanning

Method of Synthesis or Extraction of Ethylhexyl stearate:
Ethylhexyl stearate can be synthesized by the esterification of stearic acid with 2-ethylhexanol.
The reaction is catalyzed by an acid catalyst, such as sulfuric acid or p-toluenesulfonic acid.

The efficiency and yield of this method depend on the reaction conditions, such as temperature, pressure, and reaction time.
The yield of this method is typically high, ranging from 80% to 95%.
However, this method may have environmental and safety considerations, such as the use of hazardous chemicals and the generation of waste.

Chemical Structure and Biological Activity of Ethylhexyl stearate:
Ethylhexyl stearate has a chemical formula of C24H48O2 and a molecular weight of 368.64 g/mol.
Ethylhexyl stearate is a colorless to pale yellow liquid with a faint odor.

Ethylhexyl stearate has been shown to have various biological activities, including anti-inflammatory, antioxidant, and antimicrobial activities.
Ethylhexyl stearate acts by inhibiting the production of pro-inflammatory cytokines, scavenging free radicals, and disrupting the cell membrane of microorganisms.

Biological Effects of Ethylhexyl stearate:
Ethylhexyl stearate has been shown to have potential therapeutic effects on various diseases, such as acne, psoriasis, and atopic dermatitis.
Ethylhexyl stearate can improve skin hydration, reduce skin irritation, and enhance the penetration of active ingredients.

However, Ethylhexyl stearate may also have potential toxic effects, such as skin sensitization, eye irritation, and reproductive toxicity.
The toxicity of Ethylhexyl stearate depends on the dose, exposure route, and duration.

General Manufacturing Information of Ethylhexyl stearate:

Industry Processing Sectors:
All Other Chemical Product and Preparation Manufacturing
Computer and Electronic Product Manufacturing
Electrical Equipment, Appliance, and Component Manufacturing
Fabricated Metal Product Manufacturing
Machinery Manufacturing
Miscellaneous Manufacturing
Oil and Gas Drilling, Extraction, and Support activities
Petroleum Lubricating Oil and Grease Manufacturing
Printing Ink Manufacturing
Printing and Related Support Activities
Soap, Cleaning Compound, and Toilet Preparation Manufacturing
Textiles, apparel, and leather manufacturing
Transportation Equipment Manufacturing

Functions of Ethylhexyl stearate:
According to Chemiplast, a Belgian researcher, Ethylhexyl stearate is used as an oil component for emulsions, bath oils, and as a solvent for active substances in cosmetics.
Stearate esters are used most frequently in the formulation of eye makeup, skin makeup, lipstick and skin care products.

Properties of Ethylhexyl stearate:
Ethylhexyl stearate is a clear liquid ester that is free of suspended matter, although Ethylhexyl stearate may also be a waxy solid.
Colorless in its liquid form, Ethylhexyl stearate produces a faint odor.

Ethylhexyl stearate is soluble in many organic solvents, although Ethylhexyl stearate is insoluble in water and Ethylhexyl stearate can also dissolve other substances.
When applied to the skin, Ethylhexyl stearate will leave a thin coating upon drying.
Ethylhexyl stearate also reduces the thickness of lipsticks.

Storage of Ethylhexyl stearate:
Ethylhexyl stearate at normal temperatures and provide adequate ventilation.
Keep Ethylhexyl stearate from contacting oxidizing agents and observe all local regulations regarding safe product disposal.

Safety of Ethylhexyl stearate:
The Ethylhexyl stearate safety sheet indicates this chemical product is not hazardous.
However, Ethylhexyl stearate can cause irritation to the eyes or when ingested, although Ethylhexyl stearate is unlikely to cause skin irritation.
Ethylhexyl stearate will remain stable under typical handling and working conditions.

Safety Measures/Side Effects:
The CIR Expert Panel notes that the safety of the stearate esters has been assessed in a number of studies.
They have low acute oral toxicity and are essentially non-irritating to the eyes.
At cosmetic use concentrations, the stearate esters were, at most, minimally irritating to skin.

Identifiers of Ethylhexyl stearate:
CAS No.: 22047-49-0
Chemical Name: 2-ETHYLHEXYL STEARATE
CBNumber: CB8120607
Molecular Formula: C26H52O2
Molecular Weight: 396.69
MDL Number: MFCD00072275

Properties of Ethylhexyl stearate:
Appearance @ 20°C: Clear to light yellow liquid
Acid value (MGKOH/G): 1 Maximum
Saponification value: 142-156
Iodine value (WIJS): 1 Maximum
Hydroxyl value (MGKOH/G): 3 Maximum
Refractive index @ 25°C: 1.445-1.448
Specific gravity @25°C: 0.850-0.860

Density: 0.86g/cm3
Boiling Point: 438.7ºC at 760mmHg
Molecular Formula: C26H52O2
Molecular Weight: 396.69000
Flash Point: 225.6ºC
Exact Mass: 396.39700
PSA: 26.30000
LogP: 9.15160
Vapour Pressure: 6.79E-08mmHg at 25°C
Index of Refraction: 1.451

Boiling point: 420.33°C (rough estimate)
Density: 0.8789 (rough estimate)
vapor pressure: 0Pa at 20℃
refractive index: 1.4563 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Hexanes (Slightly)
form: Oil
color: Colourless
Specific Gravity: 0.826
InChI: InChI=1S/C26H52O2/c1-4-7-9-10-11-12-13-14-15-16-17-18-19-20-21-23-26(27)28-24-25(6-3)22-8-5-2/h25H,4-24H2,1-3H3
InChIKey: OPJWPPVYCOPDCM-UHFFFAOYSA-N
SMILES: C(OCC(CC)CCCC)(=O)CCCCCCCCCCCCCCCCC
LogP: 11.994 (est)

Molecular Weight: 396.7 g/mol
XLogP3-AA: 11.7
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 23
Exact Mass: 396.396730897 g/mol
Monoisotopic Mass: 396.396730897 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Count: 28
Complexity: 314
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Related Products of Ethylhexyl stearate:
(2'S)-Nicotine 1-Oxide-d4
rac-Nicotine 1-Oxide-d4
1,7-Dimethyl-1H-imidazo[4,5-g]quinoxalin-2-amine
Disulfoton Sulfone
Disulfoton

Names of Ethylhexyl stearate:

IUPAC names:
2-ethylhexyl octadecanoate
2-Ethylhexyl Stearate
2-Ethylhexyl stearate
2-ethylhexyl stearate
2-ethylhexyl stearate
LINCOL 60 LINCOL OS
octadecanoic acid, 2-ethylhexyl ester
Octadecanoic acid, 2-ethylhexyl ester + Hexadecanoic acid, 2-ethylhexyl ester
octyl octadecanoate
Viscostatic E20
Ethylhexyl Triazone
benzoic acid, 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-, tris(2-ethylhexyl) ester; octyl triazone; ethyl hexyl triazone CAS NO:88122-99-0
ETHYLHEXYLGLYCERIN
ETHYLHEXYLGLYCERYL PALMITATE. Nom INCI : ETHYLHEXYLGLYCERYL PALMITATE. Nom chimique : Hexadecanoic Acid, 3-[(2-Ethylhexyl)Oxy]-2-Hydroxypropyl Ester. Ses fonctions (INCI) Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile). Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
ETHYLHEXYLGLYCERYL PALMITATE
3-Methyloctan-3-ol; Amylethylmethylcarbinol; 2-Ethyl-2-heptanol cas no: 5340-36-3