Dodecanoic Acid is a white, powdery solid with a faint odor of bay oil or soap.
Dodecanoic Acid, Reagent, also known as Dodecoic acid, is a medium chain fatty acid that has a vague smell of soap and is a powder.
CAS Number: 143-07-7
EC Number: 205-582-1
MDL Number: MFCD00004440
Molecular formula: C10H18O4 / HOOC(CH2)8COOH
SYNONYMS:
Dodecanoic acid, n-Dodecanoic acid, Dodecylic acid, Dodecoic acid, Laurostearic acid, Vulvic acid, 1-Undecanecarboxylic acid, Duodecylic acid, C12:0 (Lipid numbers), Laurostearic acid, Laurates, NSC 5026, Vulvic acid, 1-Dodecanoic acid, Dodecanoates, Lauric acid, Dodecylic acid, 1-Undecanecarboxylic acid, FA12:0, n-Dodecanoic acid, lauric acid, n-dodecanoic acid, dodecylic acid, vulvic acid, laurostearic acid, dodecoic acid, duodecylic acid, 1-undecanecarboxylic acid, aliphat no. 4, neo-fat 12, Decanedioic acid, 1,8-Octanedicarboxylic acid, Decane-1,10-dioic acid, sebacic acid, DECANEDIOIC ACID, 111-20-6, 1,8-Octanedicarboxylic acid, 1,10-Decanedioic acid, Sebacic acids, Sebacinsaure, Decanedicarboxylic acid, n-Decanedioic acid, Acide sebacique, Sebacinsaeure, USAF HC-1, Ipomic acid, Seracic acid, Decanedioic acid, homopolymer, NSC 19492, UNII-97AN39ICTC, 1,8-dicarboxyoctane, 26776-29-4, NSC19492, 97AN39ICTC, octane-1,8-dicarboxylic acid, CHEBI:41865, NSC-19492, DSSTox_CID_6867, DSSTox_RID_78231, DSSTox_GSID_26867, SebacicAcid, CAS-111-20-6, CCRIS 2290, EINECS 203-845-5, BRN 1210591, n-Decanedioate, Iponic acid, AI3-09127, disodium-sebacate, 4-oxodecanedioate, MFCD00004440, 1,10-Decanedioate, Sebacic acid, 94%, Sebacic acid, 99%, Dicarboxylic acid C10, 1i8j, 1l6s, 1l6y, 1,8-Octanedicarboxylate, WLN: QV8VQ, SEBACIC ACID, EC 203-845-5, SCHEMBL3977, NCIOpen2_008624, SEBACIC ACID, 4-02-00-02078, SEBACIC ACID, CHEMBL1232164, DTXSID7026867, Sebacic acid, >=95.0% (GC), ZINC1531045, Tox21_201778, Tox21_303263, BBL011473, LMFA01170006, s5732, STL146585, AKOS000120056, CCG-266598, CS-W015503, DB07645, GS-6713, HY-W014787, NCGC00164361-01, NCGC00164361-02, NCGC00164361-03, NCGC00257150-01, NCGC00259327-01, BP-27864, NCI60_001628, DB-121158, FT-0696757, C08277, A894762, C10-120, C10-140, C10-180, C10-220, C10-260, C10-298, Q413454, Q-201703, Z1259273339, 301CFA7E-7155-4D51-BD2F-EB921428B436, 1,8-Octanedicarboxylic acid, Decanedioic acid, Octane-1,8-dicarboxylic acid, 1,10-Decanedioic Acid, 1,8-Octanedicarboxylic Acid, NSC 19492, NSC 97405, n-Decanedioic Acid, 1,10-Decanedioate, 1,10-Decanedioic acid, 1,8-Dicarboxyoctane, 1,8-Octanedicarboxylate, 1,8-Octanedicarboxylic acid, 4,7-Dioxosebacic acid, 4,7-dioxosebacic acid, 4-Oxodecanedioate, 4-oxodecanedioate, 4-Oxodecanedioic acid, 1,10-Decanedioic acid, 1,8-Dicarboxyoctane, Decanedioic acid, Sebacinsaeure, 1,10-Decanedioate, Decanedioate, Sebacate, 1,8-Octanedicarboxylate, 1,8-Octanedicarboxylic acid, 4,7-Dioxosebacic acid, 4-Oxodecanedioate, 4-Oxodecanedioic acid, Acide sebacique, Decanedicarboxylic acid, Dicarboxylic acid C10, Ipomic acid, N-Decanedioate, N-Decanedioic acid, Sebacic acids, Sebacinsaure, Seracic acid, Sebacic acid, aluminum salt, Sebacic acid, monocadmium salt, Sebacic acid, sodium salt, DECANEDIOIC ACID, sebacic, USAF hc-1, acidesebacique, SEBACIC ACID pure, n-Decanedioic acid, 1,10-Decanedioic acid, Decanedicarboxylic acid, sebacate (decanedioate), 1,8-OCTANEDICARBOXYLIC ACID, 1,10-Decanedioate, 1,10-Decanedioic acid, 1,8-Octanedicarboxylate, 1,8-Octanedicarboxylic acid, 4,7-Dioxosebacic acid, 4-Oxodecanedioate, 4-Oxodecanedioic acid, Acide sebacique, Decanedicarboxylic acid, Decanedioate, 1,8-Octanedicarboxylic acid, 1,10-Decanedioic acid, n-Decanedioic acid, 4-Oxodecanedioate, 1,8-Dicarboxyoctane, Octane-1,8-dicarboxylic acid, Sebacic acid, Ipomic acid, Seracic acid, lauric acid, DODECANOIC ACID, 143-07-7, n-Dodecanoic acid, Dodecylic acid, Laurostearic acid, Vulvic acid, Dodecoic acid, Duodecylic acid, 1-Undecanecarboxylic acid, Aliphat No. 4, Ninol AA62 Extra, Wecoline 1295, Hydrofol acid 1255, Hydrofol acid 1295, Duodecyclic acid, Hystrene 9512, Univol U-314, Lauric acid, pure, Dodecylcarboxylate, Lauric acid (natural), Laurinsaeure, Undecane-1-carboxylic acid, ABL, NSC-5026, FEMA No. 2614, laurate, C-1297, Philacid 1200, CCRIS 669, C12:0, Emery 651, Lunac L 70, CHEBI:30805, HSDB 6814, EINECS 205-582-1, UNII-1160N9NU9U, BRN 1099477, n-Dodecanoate, Kortacid 1299, Dodecanoic Acid Anion, DTXSID5021590, Prifrac 2920, AI3-00112, Lunac L 98, Univol U 314, Prifac 2920, 1160N9NU9U, MFCD00002736, DAO, DTXCID801590, CH3-[CH2]10-COOH, NSC5026, EC 205-582-1, dodecylate, laurostearate, vulvate, 4-02-00-01082 (Beilstein Handbook Reference), DODECANOIC ACID (LAURIC ACID), 1-undecanecarboxylate, LAURIC ACID (USP-RS), LAURIC ACID [USP-RS], CH3-(CH2)10-COOH, 8000-62-2, CAS-143-07-7, SMR001253907, laurinsaure, dodecanic acid, Nuvail, lauric-acid, Acide Laurique, 3uil, Lauric acid (NF), DODECANOICACID, fatty acid 12:0, Lauric Acid, Reagent, Nissan NAA 122, Emery 650, Dodecanoic acid, 98%, Dodecanoic acid, 99%, Guaranteed Reagent,99%, Dodecanoic (Lauric) acid, LAURIC ACID [MI], bmse000509, LAURIC ACID [FCC], LAURIC ACID [FHFI], SCHEMBL5895, NCIOpen2_009480, MLS002177807, MLS002415737, WLN: QV11, Dodecanoic acid (lauric acid), LAURIC ACID [WHO-DD], Dodecanoic acid, >=99.5%, Edenor C 1298-100, DODECANOIC ACID [HSDB], CHEMBL108766, GTPL5534, NAA 122, NAA 312, HMS2268C14, HMS3649N06, HY-Y0366, STR08039, Dodecanoic acid, analytical standard, Lauric acid, >=98%, FCC, FG, Tox21_202149, Tox21_303010, BDBM50180948, LMFA01010012, s4726, STL281860, AKOS000277433, CCG-266587, DB03017, FA 12:0, HYDROFOL ACID 1255 OR 1295, NCGC00090919-01, NCGC00090919-02, NCGC00090919-03, NCGC00256486-01, NCGC00259698-01, AC-16451, BP-27913, DA-64879, Dodecanoic acid, >=99% (GC/titration), LAU, Dodecanoic acid, purum, >=96.0% (GC), Lauric acid, natural, >=98%, FCC, FG, CS-0015078, L0011, NS00008441, EN300-19951, C02679, D10714, A808010, LAURIC ACID (CONSTITUENT OF SAW PALMETTO), Q422627, SR-01000838338, J-007739, SR-01000838338-3, BRD-K67375056-001-07-9, F0001-0507, LAURIC ACID (CONSTITUENT OF SAW PALMETTO) [DSC], Z104476194, 76C2A2EB-E8BA-40A6-8032-40A98625ED7B, Lauric acid, European Pharmacopoeia (EP) Reference Standard, Lauric acid, United States Pharmacopeia (USP) Reference Standard, Lauric Acid, Pharmaceutical Secondary Standard; Certified Reference Material, 203714-07-2, 7632-48-6, InChI=1/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14, 1-Undecanecarboxylate, 1-Undecanecarboxylic acid, ABL, Acide Laurique, C12 fatty acid, C12:0, Coconut oil fatty acids, DAO, Dodecanoate, dodecanoic acid, dodecoate, Dodecoic acid, Dodecylate, dodecylcarboxylate, Dodecylic acid, duodecyclate, Duodecyclic acid, duodecylate, Duodecylic acid, LAP, LAU, Laurate, Lauric acid, Laurinsaeure, Laurostearate, Laurostearic acid, MYR, n-Dodecanoate, n-Dodecanoic acid, Sorbitan laurate, Sorbitan monolaurate (NF), undecane-1-carboxylate, Undecane-1-carboxylic acid, Vulvate, Vulvic acid, CH3-[CH2]10-COOH, Dodecylcarboxylic acid, Laate, Laic acid, Aliphat no. 4, Edenor C 1298-100, Emery 651, Hystrene 9512, Kortacid 1299, Lunac L 70, Lunac L 98, Neo-fat 12, Neo-fat 12-43, Nissan naa 122, Philacid 1200, Prifac 2920, Univol u 314, 1-Dodecanoic acid, FA(12:0), 1-Undecanecarboxylic acid, ABL, Aliphat no. 4, C12 fatty acid, Coconut oil fatty acids, Dodecanoate, Dodecanoic (lauric) acid, Dodecanoic acid (lauric acid), Dodecoic acid, Dodecylcarboxylate, Dodecylic acid, Duodecyclic acid, Duodecylic acid, Emery 650, Lauric acid, Lauric acid, pure, Laurinsaeure, Laurostearic acid, Lunac L 70, n-Dodecanoic Acid, N-Dodecanoate, Neo-fat 12, Ninol aa62 extra, Undecane-1-carboxylic acid, Univol U 314, Univol U-314, Vulvic acid, AI3-00112, BRN 1099477, C-1297, CCRIS 669, EINECS 205-582-1, FEMA NO. 2614, HSDB 6814, HYDROFOL ACID 1255, HYDROFOL ACID 1295, HYSTRENE 9512, NEO-FAT 12-43, PHILACID 1200, PRIFRAC 2920, WECOLINE 1295, 1-Undecanecarboxylic acid, ABL, AC-16451, AC1L1GY2, AC1Q5W8C, AKOS000277433, Aliphat No. 4, CH3-[CH2]10-COOH, Coconut oil fatty acids, DAO, DODECANOIC ACID, DODECANOIC ACID (LAURIC ACID), Dodecanoate, Dodecanoic (Lauric) acid, Dodecanoic acid (lauric acid), Dodecanoic acid(Lauric acid), Dodecoic acid, Dodecylcarboxylate, Dodecylic acid, Duodecyclic acid, Duodecylic acid, Emery 650, Hydrofol acid 1255, Hydrofol acid 1295, Hystrene 9512, I04-1205, L-ALFA-LYSOPHOSPHATIDYLCHOLINE, LAUROYL, L0011, LAP, LAU, Lauric acid, pure, Laurinsaeure, Laurostearic acid, Lunac L 70, Neo-fat 12, Neo-fat 12-43, Ninol AA62 Extra, Philacid 1200, Prifrac 2920, SMR001253907, ST023796, Undecane-1-carboxylic acid, Univol U-314, Vulvic acid, Wecoline 1295, [2-((1-OXODODECANOXY-(2-HYDROXY-3-PROPANYL))-PHOSPHONATE-OXY)-ETHYL]-TRIMETHYLAMMONIUM, n-Dodecanoate, n-Dodecanoic acid, nchembio.364-comp10, Dodecanoic acid, n-Dodecanoic acid, Neo-fat 12, Aliphat no. 4, Abl, Dodecylic acid, Lauric acid, Laurostearic acid, Neo-fat 12-43, Ninol aa62 extra, Univol u-314, Vulvic acid, 1-Undecanecarboxylic acid, Duodecylic acid, C-1297, Coconut oil fatty acids, Hydrofol acid 1255, Hydrofol acid 1295, Wecoline 1295, Dodecoic acid, Hystrene 9512, Lunac L 70, Duodecyclic acid, Emery 650, n-Dodecanoate, Philacid 1200, Prifrac 2920, Undecane-1-carboxylic acid, C-1297, dodecanoic acid, dodecoic acid, duodecylic acid, ndodecanoic acid, Hydrofol acid 1255, Hydrofol acid 1295, Hystrene 9512, laurostearic acid, Neo-fat 12, Neo-fat 12-43, Ninol AA62 Extra, 1-undecanecarboxylic acid, vulvic acid, Wecoline 1295, Dodecoic acid, Duodecyclic acid, Edenor C 1298-100, Emery 650, Hydrofol acid 1295, Hystrene 9512, Kortacid 1299, Laurostearate, Lunac L 70, Lunac L 98, Neo-fat 12, Ninol AA62 extra, Nissan naa 122, Philacid 1200, Prifac 2920, Prifrac 2920, Univol U 314, Vulvate, Vulvic acid, Wecoline 1295, 1-Undecanecarboxylate, 1-Undecanecarboxylic acid, Dodecylate, Dodecylcarboxylate, Dodecylic acid, Duodecylic acid, Laurostearic acid, n-Dodecanoic acid, Undecane-1-carboxylic acid, LAP, LAU, DAO, lauric acid, n-dodecanoic acid, dodecylic acid, vulvic acid, laurostearic acid, dodecoic acid, duodecylic acid, 1-undecanecarboxylic acid, aliphat no. 4, neo-fat 12, 143-07-7, 205-582-1, 1-UNDECANECARBOXYLIC ACID, DODECANOIC ACID, DODECANOIC ACID [HSDB], DODECOIC ACID, FEMA NO. 2614, LAURATE, LAURIC ACID (CONSTITUENT OF SAW PALMETTO) [DSC], LAURIC ACID [FCC], LAURIC ACID [FHFI], LAURIC ACID [MI], LAURIC ACID [USP-RS], LAURIC ACID [WHO-DD], LAUROSTEARIC ACID, N-DODECANOIC ACID, NSC-5026, Dodecanoic acid, Lauric acid, Laurostearic acid, 1-Undecanecarboxylic acid, ABL, Aliphat No. 4, Univol U 314, Dodecylic acid, Vulvic acid, Neo-Fat 12-43, n-Dodecanoic acid, Neo-Fat 12, Lunac L 70, Emery 651, Prifac 2920, Nissan NAA 122, Lunac L 98, Hystrene 9512, NAA 312, Kortacid 1299, Philacid 1200, Edenor C 1298-100, NSC 5026, NAA 122, Prifac 2922, Edenor C 12, Prifrac 2920, ContraZeck, 1-Dodecanoic acid, Imex C 1299, Palmac 98-12, Edenor 12/98-100, Palmera B 1231, Edenor C 12-98-100, Lasacid FC 12, Laurates, Dodecanoates, Palmae 99-12, D 97385, Edenor C12-99, Coconut Hard 34, Coconut Hard 42, Radiacid 0624, NS 6, 7632-48-6, 8000-62-2, 8045-27-0, 203714-07-2, 55621-34-6, DODECANOIC ACID, C12, Emery651, Vulvic acid, FEMA 2614, lauric acid, pure, N-DODECANOIC ACID, LAUROSTEARIC ACID, Lauric acid 98-101 % (acidimetric), Fatty acid methyl ester sulfonate (MES), Dodecanoic D23 Acid, Dodecanoic Acid-d23,1-Dodecanoic Acid-d23, 1-Undecanecarboxylic Acid-d23, ABL-d23, Aliphat No. 4-d23, ContraZeck-d23, Dodecylic Acid-d23, Edenor C 12-d23,Edenor C 1298-100-d23, Emery 651-d23, Hystrene 9512-d23, Imex C 1299-d23, Kortacid 1299-d23, Laurostearic Acid-d23, Lunac L 70-d23, Lunac L 98-d23, NAA 122-d23, NAA 312-d23, NSC 5026-d23, Neo-Fat 12-d23, Neo-Fat 12-43-d23, Nissan NAA 122-d23, Philacid 1200-d23, Prifac 2920-d23, Prifac 2922-d23, Prifrac 2920-d23, Univol U 314-d23, Vulvic Acid-d23, n-Dodecanoic Acid-d23, Dodecanoate, Coconut Oil Fatty Acids, Laurostearic Acid, N-Dodecanoic Acid, C12 Fatty Acid, Duodecyclic Acid, Vulvic Acid, Dodecanoic Acid (Lauric Acid), Duodecylic Acid, N-Dodecanoate, Dodecanoic (Lauric) Acid, Laurinsaeure, Lauric Acid, Pure, Lauric Acid (Natural), Dodecylcarboxylate, Abl, Dao, Lap, Lau, Myr
Dodecanoic Acid is a saturated fatty acid with the structural formula CH3(CH2)10COOH .
Dodecanoic Acid is the main acid in coconut oil and in palm kernel oil, and is believed to have antimicrobial properties.
Dodecanoic Acid is also found in human milk(5.8% of total fat), cows milk(2.2%), and goat milk(4.5%).
Dodecanoic Acid is a white, powdery solid with a faint odor of bay oil or soap.
Dodecanoic Acid, Reagent, also known as dodecanoic acid, is a medium chain fatty acid that has a vague smell of soap and is a powder.
Dodecanoic Acid is found naturally in human breast milk as well as cow's and goat's milk.
Dodecanoic Acid's reagent grade means this is the highest quality commercially available for this chemical and that the American Chemical Society has not officially set any specifications for this material.
Dodecanoic Acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression.
Dodecanoic Acid is a solid at room temperature but melts easily in boiling water, so liquid Dodecanoic Acid can be treated with various solutes and used to determine their molecular masses.
Dodecanoic Acid is a saturated fatty acid with a 12-carbon atom chain, thus having many properties of medium-chain fatty acids.
Dodecanoic Acid is a bright white, powdery solid with a faint odor of bay oil or soap.
The salts and esters of Dodecanoic Acid are known as laurates.
Dodecanoic Acid is a saturated fatty acid with a terminal carboxylic acid.
The terminal carboxylic acid, Dodecanoic Acid, can react with primary amine groups in the presence of activators such as HATU.
Dodecanoic Acid is a carbon 13 labeled form of a saturated fatty acid found in coconut milk, coconut oil, laurel oil, and palm kernel oil, as well as in human breast milk and other animal milks.
Dodecanoic Acid is a proton pump inhibitor potentially for the treatment of helicobacter pylori infections.
In vitro experiments have suggested that some fatty acids including Dodecanoic Acid could be a useful component in a treatment for acne, but no clinical trials have yet been conducted to evaluate this potential benefit in humans.
Dodecanoic Acid increases total serum cholesterol more than many other fatty acids.
But most of the increase is attributable to an increase in high-density lipoprotein (HDL) (the "good" blood cholesterol).
As a result, Dodecanoic Acid has been characterized as having "a more favorable effect on total HDL cholesterol than any other fatty acid, either saturated or unsaturated.
Dodecanoic Acid, identified by CAS number 143-07-7, is a saturated medium-chain fatty acid with a 12-carbon atom backbone, prominently known for its role in the manufacturing of soaps, detergents, and cosmetics.
As a fundamental component, Dodecanoic Acid is celebrated for its surfactant properties, which enable the production of a rich lather in cleansing products.
In research, Dodecanoic Acid is extensively used to study lipid behavior in various systems due to its amphiphilic nature, which allows it to assemble into micelles and other nanostructures in aqueous solutions.
These studies are crucial for advancing the fields of material science and nanotechnology, particularly in the development of delivery systems and the enhancement of product formulations.
Additionally, Dodecanoic Acid is employed in food science research where it serves as a model to understand the digestion and metabolism of medium-chain fatty acids.
Dodecanoic Acid's antimicrobial properties are also examined in terms of how they can be leveraged in non-medical applications, such as in food preservation and safety, where reducing microbial growth is essential.
Moreover, Dodecanoic Acid′s role in industrial applications extends to its use as a raw material in the synthesis of various chemical derivatives, including esters used in flavorings and fragrances, showcasing its versatility and importance in both scientific research and industrial applications.
Dodecanoic Acid is a saturated medium-chain fatty acid with a 12-carbon backbone.
Dodecanoic Acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.
Dodecanoic Acid, C12H24O2, also known as dodecanoic acid, is a saturated fatty acid with a 12-carbon atom chain.
The powdery, white crystalline acid, Dodecanoic Acid, has a slight odor of oil of bay and occurs naturally in various plant and animal fats and oils.
Dodecanoic Acid is a major component of coconut oil and palm kernel oil.
Dodecanoic Acid, CAS 143-07-7, chemical formula C12H24O2, is produced as a white crystalline powder, has a slight odor of bay oil, and is soluble in water, alcohols, phenyls, haloalkanes, and acetates.
Dodecanoic Acid is non-toxic, safe to handle, inexpensive, and has a long shelf life.
Dodecanoic Acid is a saturated fatty acid with a 12-carbon atom chain, thus falling into the medium chain fatty acids.
Dodecanoic Acid is a white, powdery solid with a faint odor of bay oil or soap.
Dodecanoic Acid belongs to the class of organic compounds known as medium-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.
Dodecanoic Acid is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.
Dodecanoic Acid is a potentially toxic compound.
Dodecanoic Acid has the chemical formula C12H24O2.
Dodecanoic Acid appears as a white crystalline solid with a characteristic odor like oil of bay.
Dodecanoic Acid is insoluble in Water and soluble in Ether, Chloroform, and Alcohol.
Dodecanoic Acid is found naturally in some plant and animal fats and is a key component of coconut oil.
Dodecanoic Acid is synthetically prepared by the fractional distillation of other acids of mixed coconut.
Dodecanoic Acid is a white solid with a slight odor of bay oil.
Dodecanoic acid is a straight-chain, twelve-carbon medium-chain saturated fatty acid with strong bactericidal properties; the main fatty acid in coconut oil and palm kernel oil.
Dodecanoic Acid has a role as a plant metabolite, an antibacterial agent and an algal metabolite.
Dodecanoic Acid is a straight-chain saturated fatty acid and a medium-chain fatty acid.
Dodecanoic Acid is a conjugate acid of a dodecanoate.
Dodecanoic Acid derives from a hydride of a dodecane.
Dodecanoic Acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression.
Dodecanoic Acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can be treated with various solutes and used to determine their molecular masses.
Dodecanoic acid is a metabolite found in or produced by Escherichia coli.
Dodecanoic Acid is a natural product found in Ipomoea leptophylla, Arisaema tortuosum, and other organisms with data available.
Dodecanoic Acid is a saturated medium-chain fatty acid with a 12-carbon backbone.
Dodecanoic Acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.
Dodecanoic Acid is the main fatty acid in coconut oil and in palm kernel oil, and is believed to have antimicrobial properties.
Dodecanoic Acid is a white, powdery solid with a faint odor of bay oil.
Dodecanoic Acid, although slightly irritating to mucous membranes, has a very low toxicity and so is used in many soaps and shampoos.
Dodecanoic Acid is a metabolite found in or produced by Saccharomyces cerevisiae.
Dodecanoic Acid is a medium-chain saturated fatty acid.
Dodecanoic Acid is found in many vegetable fats and in coconut and palm kernel oils.
Dodecanoic Acid is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Dodecanoic Acid is a saturated fatty acid with a 12-carbon atom chain, thus having many properties of medium-chain fatty acids.
Dodecanoic Acid is a bright white, powdery solid with a faint odor of bay oil or soap.
The salts and esters of Dodecanoic Acid are known as laurates.
Dodecanoic Acid is a precursor to dilauroyl peroxide, a common initiator of polymerizations.
Dodecanoic Acid belongs to the class of organic compounds known as medium-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.
Dodecanoic Acid, also known as dodecanoate or lauric acid, belongs to the class of organic compounds known as medium-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.
Dodecanoic acid is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.
Dodecanoic acid is the main fatty acid in coconut oil and in palm kernel oil, and is believed to have antimicrobial properties.
Dodecanoic Acid is a white, powdery solid with a faint odour of bay oil.
Dodecanoic acid, although slightly irritating to mucous membranes, has a very low toxicity and so is used in many soaps and shampoos.
Dodecanoic Acid is a fatty acid that has been shown to inhibit the growth of bacteria.
Dodecanoic Acid inhibits bacterial growth by binding to the active site of the enzyme dihydrolipoamide acetyltransferase, which catalyzes the conversion of dihydrolipoamide and acetyl-CoA to succinyl-CoA and acetoacetyl-CoA.
Dodecanoic acid also binds to dinucleotide phosphate, which is involved in regulation of phase transition temperature and biological samples.
Dodecanoic acid has also been shown to act as an active inhibitor of fatty acid synthase, an enzyme that catalyzes the synthesis of fatty acids from acetyl-coenzyme A (acetyl-CoA).
This process is essential for bacterial growth.
Dodecanoic acid has synergistic effects with other antibiotics such as ampicillin, erythromycin, and tetracycline.
Dodecanoic Acid is a saturated medium-chain fatty acid with a 12-carbon backbone.
Dodecanoic Acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.
Dodecanoic Acid is a medium-length long-chain fatty acid, or lipid, that makes up about half of the fatty acids within coconut oil.
Dodecanoic Acid’s a powerful substance that is sometimes extracted from the coconut for use in developing monolaurin.
Monolaurin is an antimicrobial agent that is able to fight bacteria, viruses, yeasts, and other pathogens.
Because you can’t ingest Dodecanoic Acid alone (it’s irritating and not found alone in nature), you’re most likely to get it in the form of coconut oil or from fresh coconuts.
Though coconut oil is being studied at a breakneck pace, much of the research doesn’t pinpoint what in the oil is responsible for its reported benefits.
Because coconut oil contains much more than just Dodecanoic Acid, it would be a stretch to credit it with all of the coconut oil benefits.
Still, a 2015 analysis suggests that many of the benefits tied to coconut oil are directly linked to Dodecanoic Acid.
Among the benefits, they suggest Dodecanoic Acid could aid weight loss and even protect against Alzheimer’s disease.
Its effects on blood cholesterol levels still need to be clarified.
This research suggests that the benefits of Dodecanoic Acid are due to how the body uses it.
The majority of Dodecanoic Acid is sent directly to the liver, where it’s converted to energy rather than stored as fat.
When compared with other saturated fats, Dodecanoic Acid contributes the least to fat storage.
Dodecanoic Acid is a saturated fatty acid with a 12-carbon atom chain, thus having many properties of medium-chain fatty acids.
Dodecanoic Acid is a bright white, powdery solid with a faint odor of bay oil or soap.
The salts and esters of Dodecanoic Acid are known as laurates.
Like many other fatty acids, Dodecanoic Acid is inexpensive, has a long shelf-life, and is non-toxic and safe to handle.
Dodecanoic Acid is mainly used for the production of soaps and cosmetics.
For these purposes, Dodecanoic Acid is neutralized with sodium hydroxide to give sodium laurate, which is a soap.
Most commonly, sodium laurate is obtained by saponification of various oils, such as coconut oil.
These precursors give mixtures of sodium laurate and other soaps. Dodecanoic Acid occurs as a white crystalline powder
Dodecanoic Acid is a saturated fatty acid with a 12-carbon atom chain used in industrial cleaners, lubricants, soaps, surfactants, agricultural additives, coatings, food additives, textile additives.
Dodecanoic Acid, the saturated fatty acid with a 12-carbon atom chain, thus falling into the medium chain fatty acids, is a white, powdery solid with a faint odor of bay oil or soap.
Dodecanoic Acid, as a component of triglycerides, comprises about half of the fatty acid content in coconut oil, laurel oil, and in palm kernel oil.
Otherwise Dodecanoic Acid is relatively uncommon.
Dodecanoic Acid increases total serum cholesterol the most of any fatty acid.
But most of the increase is attributable to an increase in high-density lipoprotein (HDL) (the "good" blood cholesterol).
As a result, Dodecanoic Acid has been characterized as having "a more favorable effect on total:HDL cholesterol than any other fatty acid, either saturated or unsaturated."
In general, a lower total/HDL serum cholesterol ratio correlates with a decrease in atherosclerotic risk.
For these purposes, Dodecanoic Acid is neutralized with sodium hydroxide to give sodium laurate, which is a soap.
Dodecanoic Acid is a saturated fatty acid with a 12-carbon atom chain, thus falling into the medium chain fatty acids.
Dodecanoic Acid is a white crystalline carboxylic acid with a faint odor of bay oil or soap.
Dodecanoic Acid has been found at high levels in coconut oil.
Dodecanoic Acid induces the activation of NF-κB and the expression of COX-2, inducible nitric oxide synthase (iNOS), and IL-1α in RAW 264.7 cells when used at a concentration of 25 μM.
Dodecanoic Acid is a straight-chain, twelve-carbon medium-chain saturated fatty acid with strong bactericidal properties; the main fatty acid in coconut oil and palm kernel oil.
Dodecanoic Acid has a role as a plant metabolite, an antibacterial agent and an algal metabolite.
Dodecanoic Acid is a straight-chain saturated fatty acid and a medium-chain fatty acid.
Dodecanoic Acid is a conjugate acid of a dodecanoate.
Dodecanoic Acid derives from a hydride of a dodecane.
Dodecanoic Acid is a white crystalline carboxylic acid.
Dodecanoic Acid is used as a plasticizer and for making detergents and soaps.
Dodecanoic Acid's glycerides occur naturally in coconut and palm oils.
Dodecanoic Acid is a white solid with a slight odor of bay oil.
Dodecanoic Acid belongs to the class of organic compounds known as medium-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.
Dodecanoic Acid is a white, powdery solid with a faint odour of mild fatty coconut bay oil or soap.
Dodecanoic Acid is the main fatty acid in coconut oil (49%) and in palm kernel oil (47-50%), and is found in lesser amounts in wild nutmeg, human breast milk, cow’s milk, goat milk, watermelon seeds, plum and macadamia nut.
Dodecanoic Acid, although slightly irritating to mucous membranes, has an extremely low toxicity, is inexpensive, has antimicrobial properties and so is used in many soaps and shampoos.
Dodecanoic Acid is a weakly acidic compound.
Dodecanoic Acid is reacted with sodium hydroxide to generate sodium laurate, which is soap.
Dodecanoic acid has been characterized as having "a more favorable effect on total HDL cholesterol than any other fatty acid either saturated or unsaturated"
USES and APPLICATIONS of DODECANOIC ACID:
Dodecanoic Acid is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Dodecanoic Acid is approved for use as a biocide in the EEA and/or Switzerland, for: repelling or attracting pests.
People also use Dodecanoic Acid as medicine.
People use Dodecanoic Acid for viral infections such as the flu, common cold, genital herpes, and many other conditions, but there is no good scientific evidence to support any use.
Dodecanoic Acid is used in the following products: washing & cleaning products, coating products, fillers, putties, plasters, modelling clay, finger paints, polishes and waxes, air care products and plant protection products.
Other release to the environment of Dodecanoic Acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Release to the environment of Dodecanoic Acid can occur from industrial use: industrial abrasion processing with high release rate (e.g. sanding operations or paint stripping by shot-blasting) and industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).
Other release to the environment of Dodecanoic Acid is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).
Dodecanoic Acid can be found in complex articles, with no release intended: vehicles and machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines).
Dodecanoic Acid is also used as a food additive and an active component in a treatment for acne.
Dodecanoic Acid can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture) and paper used for packaging (excluding food packaging).
Dodecanoic Acid is used in the preparation of cosmetics, soaps, alkyd resins and wetting agents.
Dodecanoic Acid is also used to measure the molar mass of an unknown substance through freezing point depression.
Dodecanoic Acid is also used as a food additive and an active component in a treatment for acne.
In addition to this, Dodecanoic Acid is a substrate for acylation of certain proteins based on the murine studies.
Dodecanoic Acid is used in the preparation of cosmetics, soaps, alkyd resins and wetting agents.
Dodecanoic Acid is also used to measure the molar mass of an unknown substance through freezing point depression.
In addition to this, Dodecanoic Acid is a substrate for acylation of certain proteins based on the murine studies.
Dodecanoic Acid is used in the following products: washing & cleaning products, polishes and waxes, adhesives and sealants, cosmetics and personal care products and laboratory chemicals.
Dodecanoic Acid is used in the following areas: formulation of mixtures and/or re-packaging and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Dodecanoic Acid is used for the manufacture of: textile, leather or fur.
Release to the environment of Dodecanoic Acid can occur from industrial use: formulation of mixtures and in processing aids at industrial sites.
Other release to the environment of Dodecanoic Acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Dodecanoic Acid is used in the following products: polymers, pH regulators and water treatment products, leather treatment products, coating products, fillers, putties, plasters, modelling clay, finger paints, inks and toners, cosmetics and personal care products, lubricants and greases and textile treatment products and dyes.
Release to the environment of Dodecanoic Acid can occur from industrial use: formulation of mixtures and formulation in materials.
Dodecanoic Acid is used in the following products: washing & cleaning products, leather treatment products, polymers, textile treatment products and dyes, pH regulators and water treatment products and lubricants and greases.
Dodecanoic Acid is used in the following areas: formulation of mixtures and/or re-packaging and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Dodecanoic Acid is used for the manufacture of: textile, leather or fur.
Release to the environment of Dodecanoic Acid can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid and as processing aid.
Release to the environment of Dodecanoic Acid can occur from industrial use: manufacturing of the substance.
Dodecanoic Acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression.
Dodecanoic Acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can be treated with various solutes and used to determine their molecular masses.
In the laboratory, Dodecanoic Acid may be used to investigate the molar mass of an unknown substance via the freezing-point depression.
The choice of Dodecanoic Acid is convenient because the melting point of the pure compound is relatively high (43.8°C).
Its cryoscopic constant is 3.9°C·kg/mol.
By melting Dodecanoic Acid with the unknown substance, allowing it to cool, and recording the temperature at which the mixture freezes, the molar mass of the unknown compound may be determined.
In industry, Dodecanoic Acid is used as an intermediate and as a surface active agent.
Industrial applications of Dodecanoic Acid and its derivatives include the fatty acid as a component of alkyd resins, wetting agents, a rubber accelerator and softener, detergents, and insecticides.
The consumer market uses Dodecanoic Acid in the cleaning, furnishing, and production of personal care products.
In medicine, Dodecanoic Acid is known to increase total serum cholesterol more than many of the other fatty acids.
Common Uses and Applications of Dodecanoic Acid: Additive, Acidifiers, Chemical intermediate, Lubricant, Synthesis of substances, Industries, Chemical Production, Personal Care, and Laboratories.
Dodecanoic Acid is mainly used in the manufacturing of soaps and other cosmetics.
In scientific laboratories, Dodecanoic Acid is often used to investigate the molar mass of unknown substances via freezing-point depression.
In industry, Dodecanoic Acid is used as an intermediate and as a surface active agent.
The consumer market uses Dodecanoic Acid in the cleaning, furnishing, and production of personal care products.
In medicine, Dodecanoic Acid is known to increase total serum cholesterol more than many of the other fatty acids.
Dodecanoic Acid is mainly used in the manufacture and production of soaps and other cosmetics as well as scientific laboratory uses.
Dodecanoic Acid is used as an intermediate and surface active agent in industry and in the manufacture of personal care products in the consumer market.
Dodecanoic Acid is used in the preparation of cosmetics, soaps, alkyd resins and wetting agents.
Dodecanoic Acid is also used to measure the molar mass of an unknown substance through freezing point depression.
Dodecanoic Acid is also used as a food additive and an active component in a treatment for acne.
In addition to this, Dodecanoic Acid is a substrate for acylation of certain proteins based on the murine studies.
Dodecanoic Acid is used in the preparation of cosmetics, soaps, alkyd resins and wetting agents.
Dodecanoic Acid is also used to measure the molar mass of an unknown substance through freezing point depression.
Dodecanoic Acid is also used as a food additive and an active component in a treatment for acne.
In addition to this, Dodecanoic Acid is a substrate for acylation of certain proteins based on the murine studies.
Dodecanoic Acid is used in the preparation of cosmetics, soaps, alkyd resins and wetting agents.
Dodecanoic Acid is also used to measure the molar mass of an unknown substance through freezing point depression.
Dodecanoic Acid is also used as a food additive and an active component in a treatment for acne.
In addition to this, Dodecanoic Acid is a substrate for acylation of certain proteins based on the murine studies.
Dodecanoic Acid is generally used to produce cosmetic products but is also used in the laboratory to obtain the molar mass of substances.
Dodecanoic Acid, although slightly irritating to mucous membranes, has a very low toxicity and so is used in many soaps and shampoos.
Sodium lauryl sulfate is the most common Dodecanoic Acid derived compound used for this purpose.
Because Dodecanoic Acid has a non-polar hydrocarbon tail and a polar carboxylic acid head, it can interact with polar solvents (the most important being water) as well as fats, allowing water to dissolve fats.
This accounts for the abilities of shampoos to remove grease from hair.
Another use is to raise metabolism, believed to derive from Dodecanoic Acid's activation of 20% of thyroidal hormones, otherwise which lay dormant.
This is supposed from Dodecanoic Acid's release of enzymes in the intestinal tract which activate the thyroid.
This could account the metabolism-raising properties of coconut oil.
Because Dodecanoic Acid is inexpensive, has a long shelf-life, and is non-toxic and safe to handle, it is often used in laboratory investigations of melting-point depression.
Dodecanoic Acid is a solid at room temperature but melts easily in boiling water, so liquid it can be treated with various solutes and used to determine their molecular masses.
Dodecanoic Acid is widely used in cosmetics and food products.
In pharmaceutical applications Dodecanoic Acid has also been examined for use as an enhancer for topical penetration and transdermal absorption, rectal absorption, buccal delivery, and intestinal absorption.
Dodecanoic Acid is also useful for stabilizing oil-in-water emulsions.
Dodecanoic Acid has also been evaluated for use in aerosol formulations.
Dodecanoic Acid is used in the production of personal care products via the salt sodium laurate.
Dodecanoic Acid is also studied in metabolic and foodomics research for its potential impact on cardiovascular disease.
Dodecanoic Acid has been used as a reagent to synthesize MnFe2O4 magnetic nanoparticles by seed mediated growth method.
Dodecanoic Acid can undergo esterification with 2-ethylhexanol in the presence of sulfated zirconia catalyst to form 2-ethylhexanoldodecanoate, a biodiesel.
Like many other fatty acids, Dodecanoic Acid is inexpensive, has a long shelf-life, is nontoxic, and is safe to handle.
Dodecanoic Acid is used mainly for the production of soaps and cosmetics.
For these purposes, Dodecanoic Acid is reacted with sodium hydroxide to give sodium laurate, which is a soap.
Most commonly, sodium laurate is obtained by saponification of various oils, such as coconut oil.
These precursors give mixtures of sodium laurate and other soaps.
Dodecanoic Acid is used for the preparation of alkyd resins, as well as wetting agents, detergents and pesticides
Dodecanoic Acid is used for peeling vegetables and fruits with a maximum amount of 3.0g/kg.
Dodecanoic Acid is used as defoamer; GB 2760-86 provides for the spices allowed to use; used for the preparation of other food grade additives.
Dodecanoic Acid is widely used in the surfactant industry and can be, according to the classification of surfactants, divided into cationic, anionic, non-ionic and amphoteric type.
The surfactants types of dodecanoic acid are listed in the attached table of this item.
Some surfactants of the derivatives of dodecanoic acid and dodecanol are also antiseptics, such as dodecyl dimethyl benzyl ammonium chloride (geramine), dodecyl dimethyl benzyl ammonium bromide (bromo-geramine) and dodecyl dimethyl (2-phenoxyethyl) ammonium bromide (domiphen bromide).
The dodecyldimethyllammonium-2,4,5-trichlorophenolate in these derivatives can be used as citrus preservative.
Dodecanoic Acid also has many applications in plastic additives, food additives, spices and pharmaceutical industries.
Given its foaming properties, the derivatives of lauric acid (h-dodecanoic acid) are widely used as a base in the manufacture of soaps, detergents, and lauryl alcohol.
Dodecanoic Acid is a common constituent of vegetable fats, especially coconut oil and laurel oil.
Dodecanoic Acid may have a synergistic effect in a formula to help fight against mircoorganisms.
Dodecanoic Acid is a mild irritant but not a sensitizer, and some sources cite it as comedogenic.
Dodecanoic Acid is a fatty acid obtained from coconut oil and other veg- etable fats.
Dodecanoic Acid is practically insoluble in water but is soluble in alcohol, chloroform, and ether.
Dodecanoic Acid functions as a lubricant, binder, and defoaming agent.
Dodecanoic Acid is used intermediates of Liquid Crystals
Dodecanoic Acid is also used as a food additive and an active component in a treatment for acne.
-Uses of Dodecanoic Acid in Perfume:
Dodecanoic Acid is used in Butter flavors and in certain Citrus flavor types, mainly in Lemon.
The concentration of Dodecanoic Acid used may vasy from 2 to 40 ppm, calculated upon the finished consumer product.
-Pharmaceutical Applications of Dodecanoic Acid:
pharmaceutical applications it has also been examined for use as an enhancer for topical penetration and transdermal absorption, rectal absorption, buccal delivery,(14) and intestinal absorption.
Dodecanoic Acid is also useful for stabilizing oil-in-water emulsions.
Dodecanoic Acid has also been evaluated for use in aerosol formulations.
SOLUBILITY OF DODECANOIC ACID:
Dodecanoic Acid is soluble in water, benzene, acetone, alcohol, petroleum ether, dimethyl sulfoxide and dimethyl formamide.
Dodecanoic Acid is slightly soluble in chloroform.
NOTES OF DODECANOIC ACID:
Dodecanoic Acid is incompatible with bases, oxidizing agents and reducing agents.
WHERE TO FIND DODECANOIC ACID:
Dodecanoic Acid is a powerful substance that’s sometimes extracted from the coconut for use in developing monolaurin.
Monolaurin is an antimicrobial agent that’s able to fight pathogens such as bacteria, viruses, and yeasts.
OCCURRENCE OF DODECANOIC ACID:
Dodecanoic Acid, as a component of triglycerides, comprises about half of the fatty-acid content in coconut milk, coconut oil, laurel oil, and palm kernel oil (not to be confused with palm oil).
Otherwise, Dodecanoic Acid is relatively uncommon.
Dodecanoic Acid is also found in human breast milk (6.2% of total fat), cow's milk (2.9%), and goat's milk (3.1%).
In various plants:
*The palm tree Attalea speciosa, a species popularly known in Brazil as babassu – 50% in babassu oil
*Attalea cohune, the cohune palm (also rain tree, American oil palm, corozo palm or manaca palm) – 46.5% in cohune oil
*Astrocaryum murumuru (Arecaceae) a palm native to the Amazon – 47.5% in "murumuru butter"
*Coconut oil 49%
*Pycnanthus kombo (African nutmeg)
*Virola surinamensis (wild nutmeg) 7.8–11.5%
*Peach palm seed 10.4%
*Betel nut 9%
*Date palm seed 0.56–5.4%
*Macadamia nut 0.072–1.1%
*Plum 0.35–0.38%
*Watermelon seed 0.33%
*Viburnum opulus 0.24-0.33%
*Citrullus lanatus (egusi melon)
*Pumpkin flower 205 ppm, pumpkin seed 472 ppm
*Insect
*Black soldier fly Hermetia illucens 30–50 mg/100 mg fat.
ALTERNATIVE PARENTS OF DODECANOIC ACID:
*Dicarboxylic acids and derivatives
*Carboxylic acids
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds
SUBSTITUENTS OF DODECANOIC ACID:
*Medium-chain fatty acid
*Dicarboxylic acid or derivatives
*Carboxylic acid
*Carboxylic acid derivative
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Organooxygen compound
*Carbonyl group
*Aliphatic acyclic compound
COMPOUND TYPE OF DODECANOIC ACID:
*Animal Toxin
*Cosmetic Toxin
*Food Toxin
*Industrial/Workplace Toxin
*Metabolite
*Natural Compound
*Organic Compound
*Plasticizer
CHEMICAL PROPERTIES OF DODECANOIC ACID:
Dodecanoic Acid is a colorless needle-like crystals.
Dodecanoic Acid is soluble in methanol, slightly soluble in acetone and petroleum ether.
STABILITY AND STORAGE CONDITIONS OF DODECANOIC ACID:
Dodecanoic Acid is stable at normal temperatures and should be stored in a cool, dry place.
SOURCE AND PREPARATION OF DODECANOIC ACID:
Dodecanoic Acid is a fatty carboxylic acid isolated from vegetable and animal fats or oils.
For example, coconut oil and palm kernel oil both contain high proportions of Dodecanoic Acid.
Isolation from natural fats and oils involves hydrolysis, separation of the fatty acids, hydrogenation to convert unsaturated fatty acids to saturated acids, and finally distillation of the specific fatty acid of interest.
OCCURRENCE OF DODECANOIC ACID:
Dodecanoic Acid, as a component of triglycerides, comprises about half of the fatty acid content in coconut oil, laurel oil, and in palm kernel oil (not to be confused with palm oil).
Otherwise Dodecanoic Acid is relatively uncommon.
Dodecanoic Acid is also found in human breast milk ( 6.2 % of total fat), cow's milk (2.9%), and goat's milk (3.1 %).
SAFETY OF DODECANOIC ACID:
Dodecanoic Acid is widely used in cosmetic preparations, in the manufacture of food-grade additives, and in pharmaceutical formulations.
General exposure to Dodecanoic Acid occurs through the consumption of food and through dermal contact with cosmetics, soaps, and detergent products.
Occupational exposure may cause local irritation of eyes, nose, throat, and respiratory tract, although Dodecanoic Acid is considered safe and nonirritating for use in cosmetics.
No toxicological effects were observed when Dodecanoic Acid was administered to rats at 35% of the diet for 2 years.
MEDIUM-CHAIN TRIGLYCERIDES OF DODECANOIC ACID:
Medium-chain triglycerides, or fatty acids, such as Dodecanoic Acid, are characterized by a specific chemical structure that allows your body to absorb them whole.
This makes them more easily digestible--your body processes them as it would carbohydrates, and they are used as a source of direct energy.
Compared to long-chain triglycerides, the type in other saturated fats, MCTs have fewer calories per serving, roughly 8.3 calories per gram rather than the standard 9 calories per gram, according to an article in "Nutrition Review."
NUTRITIONAL AND MEDICAL ASPECTS OF DODECANOIC ACID:
Although 95% of medium-chain triglycerides are absorbed through the portal vein, only 25–30% of Dodecanoic Acid is absorbed through it.
Dodecanoic Acid induces apoptosis in cancer and promotes the proliferation of normal cells by maintaining cellular redox homeostasis.
Dodecanoic Acid increases total serum lipoproteins more than many other fatty acids, but mostly high-density lipoprotein (HDL).
As a result, Dodecanoic Acid has been characterized as having "a more favorable effect on total HDL than any other fatty acid [examined], either saturated or unsaturated".
In general, a lower total/HDL serum lipoprotein ratio correlates with a decrease in atherosclerotic incidence.
Nonetheless, an extensive meta-analysis on foods affecting the total LDL/serum lipoprotein ratio found in 2003 that the net effects of Dodecanoic Acid on coronary artery disease outcomes remained uncertain.
A 2016 review of coconut oil (which is nearly half Dodecanoic Acid) was similarly inconclusive about the effects on cardiovascular disease incidence.
INCLUDING DODECANOIC ACID IN YOUR DIET:
Dodecanoic Acid can be taken as a supplement, but it is most commonly consumed as part of coconut oil or palm kernel oil.
Dodecanoic Acid is considered to be safe based on the amounts generally found in food.
According to NYU Langone Medical Center, coconut and palm kernel oil contain up to 15 percent MCTs, along with a number of other fats.
However, because they are still pure oil, limit your intake of MCTs to stay within the recommended 5 to 7 teaspoons of oil per day as set out by the U.S. Department of Agriculture.
You can use coconut and palm kernel oil for stir-fries because both oils withstand high heat.
They can also be used in baking, adding a natural richness to your food.
PHYSICAL PROPERTIES OF DODECANOIC ACID:
Dodecanoic Acid occurs as a white crystalline powder with a slight odor of bay oil or a fatty odor.
Dodecanoic Acid is a common constituent of most diets; large doses may produce gastrointestinal upset.
CHEMICAL PROPERTIES OF DODECANOIC ACID:
Like many other fatty acids, Dodecanoic Acid is inexpensive, has a long shelf-life, and is non-toxic and safe to handle.
Dodecanoic Acid is mainly used for the production of soaps and cosmetics.
For these purposes, Dodecanoic Acid is neutralized with sodium hydroxide to give sodium laurate, which is a soap.
Most commonly, sodium laurate is obtained by saponification of various oils, such as coconut oil.
These precursors give mixtures of sodium laurate and other soaps.
PRODUCTION METHODS OF DODECANOIC ACID:
1. Industrial production methods can be grouped into two categories:
* derived from the saponification or high temperature and pressure decomposition of natural vegetable oils and fats;
* separated from the synthetic fatty acid.
Japan mainly uses coconut oil and palm kernel oil as the raw materials for the preparation of Dodecanoic Acid.
The natural vegetable oils used to produce dodecanoic acid include coconut oil, litsea cubeba kernel oil, palm kernel oil and mountain pepper seed oil.
Other plants oil, such as palm kernel oil, tea tree seed oil and camphor tree seed oil, can also service industry to produce dodecanoic acid.
The residual C12 distillate from the extraction of Dodecanoic Acid, containing a large number of dodecenoic acid, can be hydrogenated at atmospheric pressure, without catalyst, to convert into dodecanoic acid with a yield of more than 86%.
2. Derived from the separation and purification of coconut oil and other vegetable oil.
3. Dodecanoic Acid naturally exists in coconut oil, litsea cubeba kernel oil, palm kernel oil and pepper kernel oil in the form of glyceride.
Dodecanoic Acid can be derived from the hydrolysis of natural oils and fats in industry.
The coconut oil, water and catalyst are added into the autoclave and hydrolyzed to glycerol and fatty acid at 250 ℃ under the pressure of 5MPa.
The content of dodecanoic acid is 45%~80%, and can be further distilled to obtain dodecanoic acid.
AIR AND WATER REACTIONS OF DODECANOIC ACID:
Dodecanoic Acid is insoluble in water.
AROMA THRESHOLD VALUES OF DODECANOIC ACID:
Aroma threshold values
Aroma characteristics at 1.0%: fatty, creamy, cheeselike, candle waxy with egglike richness
TASTE THRESHOLD VALUES OF DODECANOIC ACID:
Taste characteristics at 5 ppm: waxy,fatty and oily, tallowlike, creamy and dairylike with a coating mouthfeel
REACTIVITY PROFILE OF DODECANOIC ACID:
Dodecanoic Acid is a carboxylic acid.
Carboxylic acids donate hydrogen ions if a base is present to accept them.
They react in this way with all bases, both organic (for example, the amines) and inorganic.
Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat.
Neutralization between an acid and a base produces water plus a salt.
Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt.
Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry.
Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in Dodecanoic Acid to corrode or dissolve iron, steel, and aluminum parts and containers.
Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide.
The reaction is slower for dry, solid carboxylic acids.
Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide.
PRODUCTION METHODS OF DODECANOIC ACID:
Dodecanoic Acid is a fatty carboxylic acid isolated from vegetable and animal fats or oils.
For example, coconut oil and palm kernel oil both contain high proportions of Dodecanoic Acid.
Isolation from natural fats and oils involves hydrolysis, separation of the fatty acids, hydrogenation to convert unsaturated fatty acids to saturated acids, and finally distillation of the specific fatty acid of interest.
PHYSICAL and CHEMICAL PROPERTIES of DODECANOIC ACID:
Chemical formula: C10H18O4
Molar mass: 202.250 g·mol−1
Density: 1.209 g/cm3
Melting point: 131 to 134.5 °C (267.8 to 274.1 °F; 404.1 to 407.6 K)
Boiling point: 294.4 °C (561.9 °F; 567.5 K) at 100 mmHg
Solubility in water: 0.25 g/L
Acidity (pKa): 4.720, 5.450
Molecular Weight: 202.25
XLogP3: 2.1
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 9
Exact Mass: 202.12050905
Monoisotopic Mass: 202.12050905
Topological Polar Surface Area: 74.6 Ų
Heavy Atom Count: 14
Formal Charge: 0
Complexity: 157
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Physical state: powder
Color: white
Odor: No data available
Melting point/freezing point:
Melting point/range: 133 - 137 °C - lit.
Initial boiling point and boiling range: 294,5 °C at 133 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,224 g/l at 20 °C - OECD Test Guideline 105
Partition coefficient:
n-octanol/water: log Pow: 1,5 at 23 °C
Vapor pressure: 1 hPa at 183 °C
Density: 1,210 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Water Solubility: 0.91 g/L
logP: 1.93
logP: 2.27
logS: -2.4
pKa (Strongest Acidic): 4.72
Physiological Charge: -2
Hydrogen Acceptor Count: 4
Hydrogen Donor Count: 2
Polar Surface Area: 74.6 Ų
Rotatable Bond Count: 9
Refractivity: 51.14 m³·mol⁻¹
Polarizability: 22.61 ų
Number of Rings: 0
Bioavailability: Yes
Rule of Five: Yes
Ghose Filter: Yes
Veber's Rule: No
MDDR-like Rule: No
Melting point: 133-137 °C (lit.)
Boiling point: 294.5 °C/100 mmHg (lit.)
Density: 1.21
vapor pressure: 1 mm Hg ( 183 °C)
refractive index: 1.422
Flash point: 220 °C
storage temp.: Store below +30°C.
solubility: ethanol: 100 mg/mL
form: Powder or Granules
pka: 4.59, 5.59(at 25℃)
color: White to off-white
Water Solubility: 1 g/L (20 ºC)
Merck: 14,8415
BRN: 1210591
Stability: Stable.
LogP: 1.5 at 23℃
Appearance: white granular powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 130.80 °C. @ 760.00 mm Hg
Boiling Point: 364.00 to 365.00 °C. @ 760.00 mm Hg
Boiling Point: 235.00 to 234.00 °C. @ 10.00 mm Hg
Flash Point: 389.00 °F. TCC ( 198.30 °C. ) (est)
logP (o/w): 1.706 (est)
Soluble in: water, 1000 mg/L @ 20 °C (exp)
water, 1420 mg/L @ 25 °C (est)
Chemical formula: C12H24O2
Molar mass: 200.322 g·mol−1
Appearance: White powder
Odor: Slight odor of bay oil
Density: 1.007 g/cm³ (24 °C),
0.8744 g/cm³ (41.5 °C),
0.8679 g/cm³ (50 °C)
Melting point: 43.8 °C (110.8 °F; 316.9 K)
Boiling point: 297.9 °C (568.2 °F; 571.0 K),
282.5 °C (540.5 °F; 555.6 K) at 512 mmHg,
225.1 °C (437.2 °F; 498.2 K) at 100 mmHg
Solubility in water: 37 mg/L (0 °C), 55 mg/L (20 °C),
63 mg/L (30 °C), 72 mg/L (45 °C), 83 mg/L (100 °C)
Solubility: Soluble in alcohols, diethyl ether,
phenyls, haloalkanes, acetates
Solubility in methanol: 12.7 g/100 g (0 °C),
120 g/100 g (20 °C), 2250 g/100 g (40 °C)
Solubility in acetone: 8.95 g/100 g (0 °C),
60.5 g/100 g (20 °C), 1590 g/100 g (40 °C)
Solubility in ethyl acetate: 9.4 g/100 g (0 °C),
52 g/100 g (20°C), 1250 g/100 g (40°C)
Solubility in toluene: 15.3 g/100 g (0 °C),
97 g/100 g (20°C), 1410 g/100 g (40°C)
log P: 4.6
Vapor pressure: 2.13·10−6 kPa (25 °C),
0.42 kPa (150 °C),
6.67 kPa (210 °C)
Acidity (pKa): 5.3 (20 °C)
Thermal conductivity: 0.442 W/m·K (solid),
0.1921 W/m·K (72.5 °C),
0.1748 W/m·K (106 °C)
Refractive index (nD): 1.423 (70 °C),
1.4183 (82 °C)
Viscosity: 6.88 cP (50 °C), 5.37 cP (60 °C)
Structure:
Crystal structure: Monoclinic (α-form),
Triclinic, aP228 (γ-form)
Space group: P21/a, No. 14 (α-form), P1, No. 2 (γ-form)
Point group: 2/m (α-form)[8], 1 (γ-form)[9]
Lattice constant: a = 9.524 Å, b = 4.965 Å,
c = 35.39 Å (α-form),
α = 90°, β = 129.22°, γ = 90°
Thermochemistry:
Heat capacity (C): 404.28 J/mol·K
Std enthalpy of formation (ΔfH⦵298): −775.6 kJ/mol
Std enthalpy of combustion (ΔcH⦵298): 7377 kJ/mol,
7425.8 kJ/mol (292 K)
Molecular Weight: 200.32 g/mol
XLogP3: 4.2
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 10
Exact Mass: 200.177630004 g/mol
Monoisotopic Mass: 200.177630004 g/mol
Topological Polar Surface Area: 37.3Ų
Heavy Atom Count: 14
Formal Charge: 0
Complexity: 132
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
IUPAC Name: dodecanoic acid
Traditional IUPAC Name: lauric acid
Formula: C12H24O2
InChI: InChI=1S/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14)
InChI Key: POULHZVOKOAJMA-UHFFFAOYSA-N
Molecular weight: 200.3178
Exact mass: 200.177630012
SMILES: CCCCCCCCCCCC(O)=O
Chemical Formula: C12H24O2
Average Molecular Weight: 200.3178
Monoisotopic Molecular Weight: 200.177630012
IUPAC Name: dodecanoic acid
Traditional Name: lauric acid
CAS Registry Number: 143-07-7
SMILES: CCCCCCCCCCCC(O)=O
InChI Identifier: InChI=1S/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14)
InChI Key: POULHZVOKOAJMA-UHFFFAOYSA-N
Synonyms: n-Dodecanoic acid
IUPAC Name: Dodecanoic acid
Canonical SMILES: CCCCCCCCCCCC(=O)O
InChI: POULHZVOKOAJMA-UHFFFAOYSA-N
InChI Key: InChI=1S/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14)
Boiling Point: 225 °C 100mmHg(lit.)
Melting Point: 44-46 °C(lit.)
Flash Point: 156ºC
Density: 0.883g/ml
Appearance: Clear liquid
Storage: Room temperature
CNo.Chain: C12:0
Compound Derivative: Acid
EC Number: 205-582-1
Fatty Acid: Dodecanoic (Lauric)
Hazard Codes: Xi
Hazard Statements: Xi
HS Code: 2916399090
LogP: 3.99190
MDL Number: MFCD00002736
Physical State: Solid
PSA: 37.3
Refractive Index: 1.4304
Safety Description: 37/39-26-39-36
Stability: Stable.
Incompatible with bases, oxidizing agents, reducing agents.
Storage Conditions: Store in a tightly closed container.
Store in a cool, dry, well-ventilated area away from incompatible substances.
Supplemental Hazard Statements: H401-H318-H319
Symbol: GHS05, GHS07
Vapor Pressure: 1 mm Hg ( 121 °C)
Formula: C12H24O2
InChI: InChI=1S/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14)
InChIKey: POULHZVOKOAJMA-UHFFFAOYSA-N
Molecular Weight: 200.322 g/mol
SMILES: OC(CCCCCCCCCCC)=O
SPLASH: splash10-0706-9000000000-b974e08e305014657f85
Source of Spectrum: HE-1982-0-0
CB Number: CB0357278
Molecular Formula: C12H24O2
Lewis structure
Molecular Weight: 200.32
MDL Number: MFCD00002736
MOL File: 143-07-7.mol
Melting point: 44-46 °C (lit.)
Boiling point: 225 °C/100 mmHg (lit.)
Density: 0.883 g/mL at 25 °C (lit.)
Vapor pressure: 1 mm Hg (121 °C)
Refractive index: 1.4304
FEMA: 2614 | LAURIC ACID
Flash point: >230 °F
Storage temp.: 2-8°C
Solubility: 4.81 mg/L
Form: Crystalline Powder of Flakes
pKa: 4.92 (H2O, t =25.0) (Uncertain)
Specific Gravity: 0.883
Color: White
Odor: at 100.00 % mild fatty coconut bay oil
Odor Type: fatty
Explosive limit: 0.6% (V)
Water Solubility: insoluble
λmax: 207 nm (MeOH) (lit.)
JECFA Number: 111
Merck: 14,5384
BRN: 1099477
Stability: Stable.
Incompatible with bases, oxidizing agents, reducing agents.
InChIKey: POULHZVOKOAJMA-UHFFFAOYSA-N
LogP: 5
Dissociation constant: 5.3 at 20°C
Substances Added to Food (formerly EAFUS): LAURIC ACID
CAS DataBase Reference: 143-07-7 (CAS DataBase Reference)
EWG's Food Scores: 1
FDA UNII: 1160N9NU9U
NIST Chemistry Reference: Dodecanoic acid (143-07-7)
EPA Substance Registry System: Lauric acid (143-07-7)
Molecular Weight: 200.32
Exact Mass: 200.32
BRN: 1099477
EC Number: 205-582-1
HS Code: 29159010
Characteristics
PSA: 37.3
XLogP3: 4.2
Appearance: White Crystalline Powder of Flakes
Density: 0.883 g/cm³ @ Temp: 20 °C
Melting Point: 44.2 °C
Boiling Point: 298.9 °C
Flash Point: >230 °F
Refractive Index: 1.4304
Water Solubility: H2O: insoluble
Storage Conditions: Store below +30°C
Vapor Pressure: 1 mm Hg (121 °C)
Toxicity: LD50 i.v. in mice: 131 ±5.7 mg/kg (Or, Wretlind)
Explosive limit: 0.6% (V)
Odor: Characteristic, like oil of bay
pKa: 5.3 (at 20 °C)
FIRST AID MEASURES of DODECANOIC ACID:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available
ACCIDENTAL RELEASE MEASURES of DODECANOIC ACID:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.
FIRE FIGHTING MEASURES of DODECANOIC ACID:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of DODECANOIC ACID:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of DODECANOIC ACID:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry
STABILITY and REACTIVITY of DODECANOIC ACID:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Conditions to avoid:
no information available
