psidium guajava fruit extract; extract of the fruit of the guava, psidium guajava l., myrtaceae; guajava pyrifera fruit extract; guava fruit extract; psidium guava fruit extract CAS NO:91770-12-6

4-Methylbenzenesulfonamide; Pasam; p-TSA; PTSA; Toluene-4-sulfonamide; 4-Toluenesulfonic Acid Amide; Para-Toluenesulphonamide; P-Tosylamide; Toluol-4-sulfonamid (German); Tolueno-4-sulfonamida (Spanish); Toluène-4-sulfonamide (French) CAS NO: 70-55-3

P-Toluenesulfonic acid (PTSA) is an organic compound with the chemical formula C7H8O3S.
P-Toluenesulfonic acid (PTSA) is a member of the class of organic compounds known as benzenesulfonic acids or toluenesulfonic acids.
The "p" in PTSA indicates the position of the substituent (sulfonic acid group) on the para position of the toluene ring.

CAS Number: 104-15-4
EC Number (EINECS): 203-180-0

PTSA, p-Methylbenzenesulfonic acid, Tosic acid, Toluene-p-sulfonic acid, p-Toluene sulphonic acid, 4-Methylbenzenesulfonic acid, Tosylate, Toluene-p-sulphonic acid, p-Toluene sulphonate, 4-Methylbenzenesulfonate, p-Toluene sulphonate, Toluene-p-sulphate, Tosyl acid, 4-Toluenesulfonic acid, p-Toluene sulphonate, 4-Toluene sulphonic acid, Tosic acid, PTSA hydrate, Tosic acid hydrate, Toluene-p-sulphonate, p-Toluene sulphonate, Tosyl acid, 4-Methylbenzenesulphonic acid, Tosylate hydrate, p-Toluene sulphonate, 4-Toluenesulfonate, 4-Methylbenzenesulfonate, Tosyl acid, p-Toluene sulphonate, 4-Toluene sulphate, Tosyl acid hydrate, Tosylate hydrate, PTSA hydrate, Toluene-p-sulphonate, Tosyl acid hydrate, Tosyl acid hydrate, Tosic acid hydrate, p-Methylbenzenesulphonic acid, 4-Toluene sulphonate, 4-Toluenesulphonic acid, Toluene-p-sulphate, Tosic acid hydrate, p-Methylbenzenesulfonic acid, 4-Methylbenzenesulphonic acid, p-Tolylsulfonic acid, Tosylate hydrate, Toluene-p-sulfonic acid, 4-Toluene sulphonate, Tosyl acid, Tosylate hydrate, Toluene-p-sulphonate, PTSA hydrate, 4-Toluenesulfonic acid, Tosyl acid



APPLICATIONS


P-Toluenesulfonic acid (PTSA) is extensively used as a catalyst in esterification reactions for the synthesis of various esters.
P-Toluenesulfonic acid (PTSA) plays a crucial role in promoting the Fisher esterification process, converting carboxylic acids and alcohols into esters.
P-Toluenesulfonic acid (PTSA) is employed in the synthesis of flavors and fragrances, contributing to the production of aromatic compounds.

P-Toluenesulfonic acid (PTSA) is a key component in the preparation of surfactants and detergents, enhancing their cleaning properties.
In pharmaceutical synthesis, PTSA serves as a catalyst for the formation of drug intermediates and active pharmaceutical ingredients (APIs).
P-Toluenesulfonic acid (PTSA) finds application in the production of specialty polymers, where it acts as a polymerization initiator.

P-Toluenesulfonic acid (PTSA) is utilized in the synthesis of plasticizers, improving the flexibility and performance of polymers.
P-Toluenesulfonic acid (PTSA) plays a role in the production of ion exchange resins, which have applications in water treatment processes.
P-Toluenesulfonic acid (PTSA) is involved in the synthesis of dyes and pigments, contributing to the vibrant coloration of textiles and materials.
In the field of organic synthesis, PTSA is used for the cleavage of protecting groups in chemical reactions.

P-Toluenesulfonic acid (PTSA) is employed in the manufacturing of photographic chemicals, contributing to the development of photographic materials.
P-Toluenesulfonic acid (PTSA) is a catalyst in the acylation of aromatic compounds, facilitating the introduction of acyl groups.
P-Toluenesulfonic acid (PTSA) is utilized in the synthesis of specialty solvents, enhancing the efficiency of certain chemical reactions.

P-Toluenesulfonic acid (PTSA) is involved in the preparation of chemical intermediates for the production of agrochemicals and pesticides.
P-Toluenesulfonic acid (PTSA) plays a role in the synthesis of pharmaceutical intermediates, contributing to the pharmaceutical industry's drug development.
P-Toluenesulfonic acid (PTSA) is used in the formulation of electrolytes for electrochemical cells and batteries.
In the production of coatings and adhesives, PTSA contributes to the formulation of bonding agents.

P-Toluenesulfonic acid (PTSA) finds application in the preparation of analytical reagents for laboratory use.
P-Toluenesulfonic acid (PTSA) is employed in the manufacturing of inkjet inks, contributing to the stability and performance of ink formulations.

P-Toluenesulfonic acid (PTSA) is utilized in the production of specialty waxes and lubricants for various industrial applications.
P-Toluenesulfonic acid (PTSA) plays a role in the synthesis of fine chemicals used in the development of high-performance materials.
P-Toluenesulfonic acid (PTSA) is involved in the formulation of heat transfer fluids, contributing to efficient heat exchange in industrial processes.

P-Toluenesulfonic acid (PTSA) is used in the preparation of chemical reagents for nucleic acid synthesis in molecular biology.
In the field of nanotechnology, PTSA is employed in the synthesis of nanomaterials with tailored properties.
P-Toluenesulfonic acid (PTSA)'s versatility and reactivity make it a valuable tool in research, development, and industrial processes across multiple sectors.

P-Toluenesulfonic acid (PTSA) is utilized as a catalyst in the synthesis of resins and adhesives, contributing to their chemical stability.
In the field of biochemistry, PTSA is involved in the preparation of reagents for peptide synthesis.
P-Toluenesulfonic acid (PTSA) finds application in the manufacturing of specialty chemicals used in the paper and pulp industry.

P-Toluenesulfonic acid (PTSA) serves as a catalyst in the acetylation of alcohols, facilitating the production of acetate esters.
P-Toluenesulfonic acid (PTSA) is employed in the synthesis of specialty coatings for corrosion protection in various industries.
In the petrochemical sector, PTSA is used in the alkylation of aromatics, a crucial step in the production of high-octane fuels.
P-Toluenesulfonic acid (PTSA) plays a role in the formulation of metal-complex dyes used in the textile and leather industries.

P-Toluenesulfonic acid (PTSA) is utilized in the synthesis of plastic additives, enhancing the properties of plastic materials.
P-Toluenesulfonic acid (PTSA) contributes to the formulation of electrolytes for supercapacitors, improving energy storage capabilities.
P-Toluenesulfonic acid (PTSA) finds application in the preparation of chemical reagents for DNA sequencing and analysis.

P-Toluenesulfonic acid (PTSA) is involved in the manufacturing of specialty resins used in the production of coatings and finishes.
In the pharmaceutical industry, PTSA is employed in the synthesis of prodrugs and pharmaceutical intermediates.
P-Toluenesulfonic acid (PTSA) is used in the production of specialty surfactants for use in cleaning and personal care products.

P-Toluenesulfonic acid (PTSA) plays a role in the synthesis of specialty waxes used in the formulation of polishes and coatings.
P-Toluenesulfonic acid (PTSA) is employed in the preparation of chemical intermediates for the production of herbicides and fungicides.
P-Toluenesulfonic acid (PTSA) is used in the synthesis of liquid crystal materials, contributing to advancements in display technologies.

In the field of nanomaterials, PTSA is utilized in the preparation of nanoparticles with tailored properties.
P-Toluenesulfonic acid (PTSA) serves as a catalyst in the transesterification of triglycerides, a key step in biodiesel production.

P-Toluenesulfonic acid (PTSA) is involved in the formulation of heat transfer fluids, contributing to efficient thermal management in industrial processes.
P-Toluenesulfonic acid (PTSA) plays a role in the synthesis of specialty plastics with enhanced thermal and mechanical properties.
P-Toluenesulfonic acid (PTSA) is used in the production of fuel cells, contributing to advancements in clean energy technologies.

P-Toluenesulfonic acid (PTSA) finds application in the preparation of chemical reagents for protein purification in biotechnology.
P-Toluenesulfonic acid (PTSA) is employed in the synthesis of antioxidants, contributing to the stabilization of materials against oxidative degradation.

P-Toluenesulfonic acid (PTSA) is used in the formulation of adhesives for bonding a variety of materials, including plastics and metals.
P-Toluenesulfonic acid (PTSA)'s applications extend to the preparation of chemical intermediates for the production of various agrochemicals and fertilizers.

P-Toluenesulfonic acid (PTSA) is utilized in the synthesis of specialty detergents, enhancing their effectiveness in removing contaminants.
P-Toluenesulfonic acid (PTSA) plays a role in the formulation of corrosion inhibitors for protecting metal surfaces in various industrial processes.
P-Toluenesulfonic acid (PTSA) is employed in the production of specialty paints and coatings, contributing to improved adhesion and durability.

In the field of electrochemistry, PTSA is used in the preparation of electrolytes for redox flow batteries.
P-Toluenesulfonic acid (PTSA) is involved in the synthesis of ion exchange resins, which find applications in water treatment processes.
P-Toluenesulfonic acid (PTSA) is used in the production of specialty adhesives for bonding materials in challenging environments.
P-Toluenesulfonic acid (PTSA) serves as a key component in the formulation of liquid crystal materials used in the electronics and display industries.

P-Toluenesulfonic acid (PTSA) is employed in the synthesis of specialty monomers for the production of high-performance polymers.
In the field of catalysis, PTSA plays a role in asymmetric transformations, enabling the synthesis of chiral compounds.

P-Toluenesulfonic acid (PTSA) is utilized in the manufacturing of specialty lubricants, contributing to improved performance in various applications.
P-Toluenesulfonic acid (PTSA) finds application in the synthesis of photoactive materials for photonic devices and sensors.
P-Toluenesulfonic acid (PTSA) is involved in the production of specialty waxes used in formulations such as polishes and coatings.

P-Toluenesulfonic acid (PTSA) is employed in the preparation of chemical intermediates for the synthesis of pharmaceuticals and agrochemicals.
P-Toluenesulfonic acid (PTSA) serves as a reagent in the synthesis of surfactants, contributing to their emulsifying and dispersing properties.
P-Toluenesulfonic acid (PTSA) is used in the synthesis of specialty resins for the production of high-quality inks and coatings.

In the field of analytical chemistry, PTSA is employed for sample preparation and derivatization in chromatographic techniques.
P-Toluenesulfonic acid (PTSA) finds application in the production of specialty inorganic salts, utilized in various industrial processes.
P-Toluenesulfonic acid (PTSA) is utilized in the synthesis of specialty plastic materials, enhancing their thermal and mechanical properties.

P-Toluenesulfonic acid (PTSA) is involved in the formulation of electrolytes for electrochemical capacitors, contributing to their energy storage capabilities.
P-Toluenesulfonic acid (PTSA) is used in the preparation of metal-organic frameworks (MOFs), which have applications in gas storage and separation.
P-Toluenesulfonic acid (PTSA) plays a role in the synthesis of specialty polymers with controlled molecular weights and architectures.
P-Toluenesulfonic acid (PTSA) is employed in the production of corrosion-resistant coatings for metal surfaces in harsh environments.

P-Toluenesulfonic acid (PTSA) serves as a catalyst in the production of biodiesel from triglycerides, facilitating transesterification reactions.
P-Toluenesulfonic acid (PTSA) is used in the formulation of heat transfer fluids, contributing to efficient heat exchange in various industrial processes.
In the field of nanotechnology, PTSA is involved in the synthesis of nanomaterials with tailored properties for diverse applications.



DESCRIPTION


P-Toluenesulfonic acid (PTSA) is an organic compound with the chemical formula C7H8O3S.
P-Toluenesulfonic acid (PTSA) is a member of the class of organic compounds known as benzenesulfonic acids or toluenesulfonic acids.
The "p" in PTSA indicates the position of the substituent (sulfonic acid group) on the para position of the toluene ring.

P-Toluenesulfonic acid (PTSA) is a colorless to light yellow liquid with a faint odor.
Known for its strong acidity, P-Toluenesulfonic acid (PTSA) is a versatile organic compound widely used in various chemical processes.
The chemical structure of P-Toluenesulfonic acid (PTSA) consists of a toluene ring with a sulfonic acid group attached to the para position.
P-Toluenesulfonic acid (PTSA) is soluble in organic solvents and miscible in water, enhancing its applicability in different reaction environments.

P-Toluenesulfonic acid (PTSA) plays a crucial role as a catalyst in organic synthesis reactions, facilitating the formation of esters and other compounds.
As a sulfonic acid, PTSA is a powerful proton donor, making it effective in promoting acid-catalyzed reactions.

Its high reactivity and stability make PTSA a popular choice in laboratory and industrial settings for numerous applications.
P-Toluenesulfonic acid (PTSA) is commonly employed in esterification reactions for the synthesis of flavors, fragrances, and pharmaceutical intermediates.

P-Toluenesulfonic acid (PTSA)'s strong acid properties also make it valuable in acid-catalyzed dehydration reactions.
In addition to catalysis, PTSA is used in the production of specialty chemicals, detergents, and surfactants.

P-Toluenesulfonic acid (PTSA) hydrate is a hydrated form of the acid, offering specific advantages in certain applications.
P-Toluenesulfonic acid (PTSA) is often utilized in the manufacturing of polymers and plastics as a key component in the synthesis process.
P-Toluenesulfonic acid (PTSA)'s solubility in various organic solvents makes it a suitable reagent in customizing reaction conditions.

Due to its stability under proper storage conditions, PTSA is a reliable choice for chemical processes.
P-Toluenesulfonic acid (PTSA) is employed in the preparation of reagents for analytical chemistry and molecular biology applications.

P-Toluenesulfonic acid (PTSA) is known for its compatibility with a wide range of substrates, enhancing its versatility in different reactions.
P-Toluenesulfonic acid (PTSA) is a non-flammable liquid, contributing to its safety in handling and storage.
Its distinct odor, although faint, is characteristic and recognizable in laboratory environments.
P-Toluenesulfonic acid (PTSA)'s strong affinity for water makes it hygroscopic, necessitating careful handling to prevent moisture absorption.

P-Toluenesulfonic acid (PTSA) is a valuable tool in organic synthesis for introducing functional groups and modifying molecular structures.
Its effectiveness as a sulfonating agent is harnessed in the synthesis of dyes, pigments, and specialty chemicals.
P-Toluenesulfonic acid (PTSA) is often used in the synthesis of fine chemicals where precise control over reaction conditions is crucial.

P-Toluenesulfonic acid (PTSA)'s presence in various industrial processes highlights its importance in chemical manufacturing.
P-Toluenesulfonic acid (PTSA)'s impact extends to pharmaceutical research, where it serves as a catalyst in drug synthesis.
Known for its utility and reliability, PTSA continues to be a key component in the toolkit of synthetic chemists and researchers.



PROPERTIES


Chemical Formula: C7H8O3S
Molecular Weight: Approximately 172.20 g/mol
Physical State: Liquid
Color: Colorless to light yellow
Odor: Faint
Melting Point: 106-109 °C (223-228 °F)
Boiling Point: Decomposes before boiling
Density: Approximately 1.29 g/cm³
Solubility in Water: Soluble
Solubility in Organic Solvents: Miscible with many organic solvents
pH: Highly acidic
Refractive Index: Typically around 1.51
Flash Point: Non-flammable
Autoignition Temperature: Not applicable as it is non-flammable
Vapor Pressure: Negligible
Viscosity: Low viscosity liquid
Hygroscopicity: Absorbs moisture from the air
Corrosivity: Can be corrosive to certain metals and materials
Compatibility: Compatible with a wide range of organic solvents
Miscibility: Miscible with water and various organic solvents
Acidity: Strong acid with a dissociation constant (pKa) around -2
Hazardous Polymerization: Will not occur
Stability: Stable under normal storage conditions
Flammability: Non-flammable



FIRST AID


Inhalation:

Remove to Fresh Air:
If inhalation exposure occurs, immediately move the affected person to an area with fresh air.
Ensure proper ventilation and access to uncontaminated air.

Seek Medical Attention:
If respiratory distress persists or if there are signs of respiratory irritation, seek medical attention promptly.
Provide supportive care, including oxygen, if necessary.


Skin Contact:

Remove Contaminated Clothing:
In case of skin contact, promptly remove contaminated clothing to minimize further exposure.
Cut rather than pull clothing away to avoid additional skin contact.

Rinse with Water:
Rinse the affected skin area with plenty of water for at least 15 minutes.
Use mild soap if available and continue rinsing to ensure thorough removal of the substance.

Seek Medical Attention:
If irritation, redness, or chemical burns develop, seek medical attention promptly.
Provide healthcare professionals with information about the specific PTSA product and the nature of exposure.


Eye Contact:

Flush Eyes with Water:
If PTSA comes into contact with the eyes, immediately flush the eyes with gently flowing water for at least 15 minutes.
Hold the eyelids open to ensure thorough rinsing.

Seek Immediate Medical Attention:
Even if irritation is minimal, seek immediate medical attention.
Remove contact lenses after the initial eye rinse.


Ingestion:

Rinse Mouth:
If PTSA is ingested accidentally, rinse the mouth with water.
Do not induce vomiting unless instructed to do so by medical professionals.

Seek Immediate Medical Attention:
Seek immediate medical attention and provide healthcare providers with information about the ingested substance.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including chemical-resistant gloves, safety goggles or face shield, and protective clothing, to minimize skin and eye contact.
Use respiratory protection if handling in conditions where vapors or mists may be generated.

Ventilation:
Work in a well-ventilated area or use local exhaust ventilation to control airborne concentrations.
If handling in an enclosed space, ensure proper ventilation systems are in place to minimize inhalation risks.

Avoidance of Contact:
Avoid direct skin and eye contact with PTSA.
Take precautions to prevent inhalation of vapors, mists, or dust.
Minimize exposure through the use of engineering controls and PPE.

Handling Procedures:
Follow good laboratory or industrial practices when working with PTSA.
Use appropriate tools and equipment to minimize the generation of dust or aerosols during handling.

Spill Response:
In case of a spill, use suitable absorbent materials to contain and clean up the spilled substance.
Dispose of waste according to local regulations and in accordance with the product's safety data sheet (SDS).

Storage Compatibility:
Store PTSA away from incompatible materials, such as strong bases, reducing agents, and reactive metals.
Check compatibility with storage containers to prevent chemical reactions.

Labeling:
Ensure containers are properly labeled with the correct product information, hazard symbols, and safety precautions.
Maintain clear and visible labeling on secondary containers in case of transfer.


Storage:

Temperature:
Store PTSA in a cool, well-ventilated area, away from heat sources and direct sunlight.
Avoid exposure to extreme temperatures, as excessive heat may affect the stability of the substance.

Container Integrity:
Ensure that storage containers are tightly sealed to prevent contamination or evaporation.
Regularly inspect containers for any signs of damage or leaks.

Ventilation During Storage:
If stored in an enclosed area, provide adequate ventilation to prevent the accumulation of vapors.

Storage Conditions:
Store PTSA in accordance with the manufacturer's recommendations.
Keep the substance away from incompatible materials and follow guidelines for the storage of corrosive substances.

Separation from Food and Feed:
Store PTSA away from food, beverages, and animal feed.
Use separate storage areas to avoid cross-contamination.

Handling Precautions:
Follow proper handling procedures when transferring PTSA between containers or dispensing it for use.
Minimize the risk of spills during storage and handling.

Fire Prevention:
PTSA is generally non-flammable, but it is advisable to keep it away from open flames, sparks, or potential ignition sources.
Store in areas compliant with fire safety regulations.

Emergency Response:
Have appropriate emergency response equipment, such as spill containment materials and fire extinguishers, readily available.

cas no 70-55-3 4-Methylbenzenesulfonamide; Pasam; p-TSA; PTSA 70 ; Toluene-4-sulfonamide; 4-Toluenesulfonic Acid Amide; Para-Toluenesulphonamide; P-Tosylamide; Toluol-4-sulfonamid (German); Tolueno-4-sulfonamida (Spanish); Toluène-4-sulfonamide (French); p-TOLUENE SULFONAMIDE 70;

polyvinyl alcohol

ptychopetalum olacoides extract; extract of the bark and root of the potency wood, ptychopetalum olacoides, olacaceae; muira puama extract; muirapuama extract; potency wood extract CAS NO:84929-46-4

DESCRIPTION:

PU Catalyst DMDEE is suitable for water curing systems and is a strong foaming catalyst.
Due to the steric hindrance of amino groups, the storage period of NCO components can be prolonged.

CAS No.:6425-39-4
EC Number, 229-194-7
Chemical Name:2,2-Dimorpholinodiethylether
Molecular weight：244.33

SYNONYMS OF PU CATALYST DMDEE:
DMDEE;Niax« Catalyst DMDEE;4,4′-(oxydiethane-2,1-diyl)dimorpholine
Morpholine, 4,4'-(oxydi-2,1-ethanediyl)bis-
Bis(2-morpholinoethyl) Ether, 4,4'-(Oxybis(ethane-2,1-diyl))dimorpholine,2,2-Dimorpholinodiethylether,2,2'-Dimorpholinodiethyl ether,4,4'-(Oxydiethylene)bis(morpholine),4-[2-(2-morpholin-4-ylethoxy)ethyl]morpholine, 2,2'-Dimorpholinyldiethyl ether
4,4’-(oxydi-2,1-ethanediyl)bis-morpholin;Dimorpholinodiethylether;BIS(2-MORPHOLINOETHYL) ETHER;BIS[2-(N-MORPHOLINO)ETHYL] ETHER;LUPRAGEN(R) N 106;4,4'-(3-OXAPENTANE-1,5-DIYL)BISMORPHOLINE;4,4-(OXYDI-2,1-ETHANEDIYL)BISMORPHOLINE;2,2'-DIMORPHOLINODIETHYL ETHER



PU Catalyst DMDEE is suitable for the catalytic reaction of NCO and water in systems such as TDI, MDI, and IPDI; Sinocat® DMDEE is mainly used In one-component rigid polyurethane foam system, PU Catalyst DMDEE can also be used for polyether and polyester polyurethane soft foam, semi-rigid foam, CASE material, etc.
The addition amount accounts for 0.3-0.55% of the polyether/ester component.


PU Catalyst DMDEE is an acronym for dimorpholinodiethyl ether but is almost always referred to as DMDEE (pronounced dumdee) in the polyurethane industry.
PU Catalyst DMDEE is an organic chemical, specifically a nitrogen-oxygen heterocycle with tertiary amine functionality.

PU Catalyst DMDEE is a catalyst used mainly to produce polyurethane foam.
PU Catalyst DMDEE has the CAS number 6425-39-4 and is TSCA and REACH registered and on EINECS with the number 229-194-7.
The IUPAC name is 4-[2-(2-morpholin-4-ylethoxy)ethyl]morpholine and the chemical formula C12H24N2O3.

APPLICATIONS OF PU CATALYST DMDEE:
PU Catalyst DMDEE catalyst is a good blowing catalyst that does not cause cross-linking.
When used in moisture-cured systems, PU Catalyst DMDEE provides a stable prepolymer with a rapid cure.
PU Catalyst DMDEE can also be used in flexible polyester-based urethane foams, as well as semiflexible foams and HR molded foams.



USES OF PU CATALYST DMDEE:
PU Catalyst DMDEE tends to be used in one-component rather than 2-component polyurethane systems.
Its use has been investigated in polyurethanes for controlled drug release and also adhesives for medical applications.

Its use as a catalyst including the kinetics and thermodynamics have been studied and reported on extensively.
PU Catalyst DMDEE is a popular catalyst along with DABCO.






CHEMICAL AND PHYSICAL PROPERTIES OF PU CATALYST DMDEE:
Item, Standard
Appearance, Colorless transparent liquid
Chromaticity, ＜2
Water content, ≤0.1%
Content, ≥99%
Color Amber
Flash point, PMCC, °C (°F) 166 (330)
Freezing point, °C -28
Initial Boiling point, °C 309
pH 10.3
Specific gravity, 20/20°C 1.06
Vapor pressure, mm Hg, 20°C < 1
Viscosity, cSt, 15.5°C (60°F) 29
VOC Content, %, by ASTM D 2369 76
Water solubility, % > 10
CAS:, 6425-39-4
MF:, C12H24N2O3
MW:, 244.33
EINECS:, 229-194-7
Boiling point, 309 °C(lit.)
density, 1.06 g/mL at 25 °C(lit.)
refractive index, n20/D 1.484(lit.)
Fp, 295 °F
CAS DataBase Reference, 6425-39-4(CAS DataBase Reference)
EPA Substance Registry System, Morpholine, 4,4'-(oxydi-2,1-ethanediyl) bis-(6425-39-4)

Product Name:
Dimorpholinodiethyl ether
Other Name:
Morpholine,4,4′-(oxydi-2,1-ethanediyl)bis-;Morpholine,4,4′-(oxydiethylene)di-;4,4′-(Oxydi-2,1-ethanediyl)bis[morpholine];Bis(morpholinoethyl) ether;2,2′-Dimorpholinodiethyl ether;β,β′-Dimorpholinodiethyl ether;4,4′-(Oxydiethylene)bis[morpholine];4,4′-(Oxydiethylene)dimorpholine;Dimorpholinodiethyl ether;Texacat DMDEE;Jeffcat DMDEE;Di(2-morpholinoethyl) ether;PC CAT DMDEE;Bis[2-(4-morpholino)ethyl] ether;Dabco DMDEE;NSC 28749;U-CAT 660M;Bis(2-morpholinoethyl) ether;DMDEE;4,4′-(Oxydi-2,1-ethanediyl)bismorpholine;Lupragen N 106;N 106;JD-DMDEE;442548-14-3
CAS No.:
6425-39-4
Molecular Formula:
C12H24N2O3
InChIKeys:
InChIKey=ZMSQJSMSLXVTKN-UHFFFAOYSA-N
Molecular Weight:
244.33
Exact Mass:
244.33
EC Number:
229-194-7
UNII:
5BH27U8GG4
NSC Number:
28749
DSSTox ID:
DTXSID9042170
HScode:
2934999090
PSA:
34.2
XLogP3:
-0.6
Appearance:
Liquid
Density:
1.0682 g/cm3 @ Temp: 20 °C
Boiling Point:
176-182 °C @ Press: 8 Torr
Flash Point:
295 °F
Refractive Index:
1.482


SAFETY INFORMATION ABOUT PU CATALYST DMDEE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product

pueraria lobata root extract; extract of the roots of pueraria lobata, fabacea; kudzu root extract; kudzu root extract; actipone pueraria root CAS NO:223748-08-1

pururan; E1204; α-1,4- ;α-1,6-glucan'. CAS NO:9057-02-7

punica granatum l. bark extract ;extract of the bark of the pomegranate, punica granatum l., punicaceae; pormegranate bark extract; punica florida bark extract; punica grandiflora bark extract; punica nana bark extract; punica spinosa bark extract CAS NO:84961-57-9

amiporine ER extract of the fruit of the pomegranate, punica granatum l., punicaceae pomegranate fruit extract punica florida fruit extract punica grandiflora fruit extract punica nana fruit extract punica spinosa fruit extract CAS Number 84961-57-9

extract of the pericarp of the pomegranate, punica granatum l., punicaceae; extract of the pericarp of the pomegranate, punica granatum l., punicaceae; pomegranate extract BG30; pomegranate pericarp extract; punica florida pericarp extract; punica grandiflora pericarp extract; punica nana pericarp extract; punica spinosa pericarp extract CAS NO:84961-57-9

Purac FCC is a colorless to yellow syrupy liquid.
Purac FCC has a mild acid taste and is widely used as an acidulant in the food industry.


CAS Number: 50-21-5
EC Number: 200-018-0
INCI Names: LACTIC ACID
Molecular Formula: C3H6O3



L-lactic acid, PURAC 50-100, PURAC 80 FG, PURAC 88-LT, 88-T, PURAC FCC 50, FCC 80, FCC 85, FCC 88, PURAC FIT Plus 90, PURAC HiPure 51, HiPure 90, PURAC HS 50, HS 80, HS 88, HS 90, HS 93, HS 95, HS 100, PURAC PF 90, PURAC PH 91, PURAC UltraPure 50, UltraPure 90, PURAC Vin, PURAC DEX 185, PURAC HS Pure 90, PURAC HS Pure 50, Lactic Acid 50% NATL FCC, Purac FCC 50, Unilac LA50, Tisulac, Espiritin, HiPure 90, l-lacticaci, Lactic L-Milchsàure, α-hydroxypropionic acid, 2-hydroxypropanoic acid, 2-Hydroxypropionic acid, 2-Hydroxypropanoic acid, DL-Lactic acid, DL-Lactic acid, 2-Hydroxypropionic acid, Acidum lacticum,
Lactic Acid 80% Pdr w/silca, Lactic Acid 80% , Unilac LA80, Tisulac, Espiritin, HiPure 90, l-lacticaci, Lactic L-Milchsàure, α-Hydroxypropanoic acid,
lactic acid, 2-hydroxypropanoic acid, DL-Lactic acid, 50-21-5, 2-hydroxypropionic acid,



Purac FCC is the natural L(+) lactic acid, which is produced by fermentation from sugar.
Purac FCC’ s primary functions are to preserve and flavor.


Purac FCC is used organic acid for industrial purposes.
Purac FCC is a hydroxycarboxylic acid, so it contains both a carboxyl group and a hydroxyl group.
Purac FCC is therefore also referred to as 2-hydroxypropionic acid, but according to IUPAC nomenclature recommendations, the name 2-hydroxypropionic acid should be used.


Purac FCC's Chemical Formula is C3H6O3.
Purac FCC is produced as natural L-Lactic acid by fermentation of carbohydrates like sugar or starch.


Purac FCC is used in cosmetic compositions for pH adjustment and has good affinity for skin and hair.
Purac FCC improves skin hydration, removes dead cells and hair films (dandruff) having keratolytic action, hair shines.
Purac FCC is responsible for the tang that hits the mouth when eating dry aged beef.


Purac FCC is produced as natural L-Lactic acid by fermentation of carbohydrates like sugar or starch.
Purac FCC's Chemical Formula is C3H6O3.
An organic acid, Purac FCC, is used to reduce alkalinity without adding sulphate and chloride ions.


Purac FCC can help stimulate collagen and strengthen the skin, which equals fewer fine lines and wrinkles.
The hydroxy acids exfoliate the top layer of skin, helping smooth and even complexion, keep pores unclogged, brighten skin and even fade dark marks and discoloration.


Purac FCC is a versatile organic acid.
Purac FCC is soluble in water and in ethanol.
The inclusion of additional Purac FCC prior to rennetting overcomes this shortage and improves the curd yield.


The salts and esters of Purac FCC are called lactates.
A concentrated solution of Purac FCC is typically a mixture of lactic acid lactate and lactic acid.
Purac FCC appears as a colorless to yellow odorless syrupy liquid.


Purac FCC is a colorless to yellow/brown liquid.
Store Purac FCC in a tightly closed container.
Store Purac FCC in a cool, dry, well-ventilated area away from incompatible substances.


Purac FCC can also be used for minor corrections in brewing PH can be used at higher levels for beer souring.
Purac FCC reduces the alkalinity levels of brewing liquor, stimulating maximum enzyme activity in the wort and enabling optimum pH levels throughout the whole brewing process.


Purac FCC improves extract yield and fermentation ability.
Purac FCC is suitable for beers where no other anions are needed, for example, lagers.
Purac FCC improves the clarity and stability of the finished product


Purac FCC is a ready-for-use acid used to reduce alkalinity in brewing liquor.
Purac FCC is Food Grade and made by fermentation of natural (beet or cane) sugar.
Purac FCC is a product of natural origin, obtained by fermentation of glucose.


Purac FCC is an Alpha Hydroxy Acid (AHA) and can be used to promote higher rates of desquamation and cell renewal.
Purac FCC is also a moistening compound.
Purac FCC belongs to a group of alpha hydroxy acids (AHA) which show exfoliating, moistening and anti-aging properties.


Purac FCC is presented in a dropper bottles holding 4fl oz, to ensure an accurate dosing of milk and achieve consistent results when cheese making.
In production, Purac FCC is usually added up so that the pH of the milk is 5.0.
The casein in fermented milk is coagulated (curdled) by Purac FCC and it is also responsible for the sour flavor of sourdough breads.


If the pH is not within the range of 5.3 - 5.8, make gradual additions (0.10 - 0.15 mL/L) of Purac FCC, mix and measure again.
Purac FCC, from Jungbunzlauer, is an organic acid, occurring naturally in the human body and in fermented foods.
Purac FCC is a natural preservative and pH regulator.


Purac FCC is an organic acid with wide-reaching industrial applications.
Purac FCC specification makes it especially useful for food and beverage production, as well as pharmaceutical and cosmetic products.
Purac FCC is a versatile organic acid.


In its liquid state Purac FCC is colourless.
Purac FCC is one of the alpha-hydroxy acids (AHA’s).
These acids occur naturally in fruits, sugar cane and milk.


Purac FCC increasing wort's acidity and improving both mashing and fermentation.
The exact dosage depends on the alkalinity of the water used, the salts added and the malts used in the recipe.
Purac FCC is recommended to carry out a pH measurement of the mash before adding the product.


In nature Purac FCC exists in sour milk, yoghurts, sour rye soups and silages.
Purac FCC appears in two optical forms L and D, out of which only L-lactic acid is biologically active and is a natural element of the skin and hair.
Purac FCC is one of the main part of NMF – natural moistening factor, which is responsible for proper hydration of the epidermis.


Purac FCC stabilizes process of epidermis exfoliation in a very delicate way.
Purac FCC is an alpha hydroxy acid with both exfoliant and humectant properties.
Purac FCC is produced naturally in the body (it's the stuff that gives you a ‘stitch’ during a workout) and is also found in yogurt and milk.


Purac FCC dissolves very well in water.
Purac FCC is natural.
Purac FCC is approved as food additive E 270.


Purac FCC is a non dairy version that is part of a family of acids called Alpha Hydroxy Acids (AHA’s).
Purac FCC is produced from natural corn starch by advanced bio-fermentation and refining technology.
Purac FCC is a yellowish to colorless liquid, with a mildly acidic odour and taste.


Purac FCC is a naturally occurring alpha hydroxy acids (or AHAs) produced by fermentation of sugars.
Purac FCC is the alpha hydroxy acid most frequently used for peel products.
Purac FCC, also known as milk acid, is an organic compound with the chemical formula C3H6O3.


Purac FCC is a strong Alpha-Hydroxy Acid and hence will have excellent exfoliant properties, although these are weaker than, but second only to, Glycolic Acid.
AHA products should be a stand alone treatment product and not included in another product.


While AHA can be included in other products there are certain incompatibilities that may arise plus AHAs (because of the pH required for best effectiveness) may not allow other products (such as cleansing masks) to work properly, and vice versa.
Purac FCC is also a widely used organic acidulate, probably because it is classified as a weak acid.


While AHA can be included in other products there are certain incompatibilities that may arise plus AHAs (because of the pH required for best effectiveness) may not allow other products (such as cleansing masks) to work properly, and vice versa.
Purac FCC is also a widely used organic acidulate, probably because it is classified as a weak acid.


As with all manufacturing processes, we recommend lab scale trials in order to determine appropriate quantities.
Purac FCC is a liquid solution in water of about 80% purity.
Purac FCC, is an organic acid with applications in beer production as well as the cosmetic, pharmaceutical, food and chemical industries.


Purac FCC is produced from natural cornstarch by advanced bio-fermentation and refining technology.
Purac FCC is a yellowish to colorless liquid, having a mild acid odor and taste.
Purac FCC appears as a colorless to yellow odorless syrupy liquid.


Store Purac FCC in a tightly closed container.
Store Purac FCC in a cool, dry, well-ventilated area away from incompatible substances
Purac FCC is a colorless to yellow syrupy liquid.


Purac FCC is an alpha hydroxy acid that comes from milk.
As a result of its relatively greater molecular weight, Purac FCC's keratolytic action is milder than that of glycolic acid, thus preventing skin irritations.


Purac FCC is a strong Alpha-Hydroxy Acid and hence will have excellent exfoliant properties, although these are weaker than, but second only to, Glycolic Acid.
AHA products should be a stand alone treatment product and not included in another product.


Purac FCC is an anti-wrinkle and anti-pigmentation component available in both over-the-counter and professional-grade skincare products.
Purac FCC is derived from milk and belongs to the alpha-hydroxy acid (AHAs) class of anti-ageing compounds.
Glycolic acid and citric acid are two further examples of AHAs.


Purac FCC is a liquid solution in water of about 80% purity.
Purac FCC is an AHA.
Purac FCC is sufficient to add a few drops to 100 ml shampoo to adjust the pH.


Even as a moisturizing additive Purac FCC should not be applied more than 0,5%.
Dilute Purac FCC before use.
As with all of the acids, Purac FCC is important to let your skin acclimate to their use.


Purac FCC, also known as milk acid, is a chemical compound that plays a role in several biochemical processes.
Purac FCC is an alpha hydroxy acid that comes from milk.
As a result of its relatively greater molecular weight, Purac FCC's keratolytic action is milder than that of glycolic acid, thus preventing skin irritations.


Purac FCC comes in both R (D-) and S (L+) enantiomers which can be manufactured individually to near perfect optical purity.
This means Purac FCC is great in the production of other products which require a specific stereochemistry.
Purac FCC is a liquid solution in water of about 80% purity.


As with all manufacturing processes, we recommend lab scale trials in order to determine appropriate quantities.
Normally Purac FCC is titrated with a dilute solution of Lactic Acid (10 or 20% in water) until the desired pH is achieved.
Purac FCC is preferred as an acidulate as it tends to have less of a destabilizing effect on emulsions than Citric Acid.


Purac FCC has a mild acid taste and is widely used as an acidulant in the food industry.
Purac FCC is lactic acid naturally produced by fermentation from sugar.
With its mild acid taste, Purac FCC is fast emerging as the beverage acidulant of choice.


Purac FCC is a natural L-lactic acid that is produced by the fermentation of sugar.
Purac FCC has a mild acid taste and is widely used as an acidulate in the food industry.
The primary purpose of Purac FCC is to preserve flavor as well as the actual product.


Purac FCC acts as a moisturizing agent used in many skin care products.
Purac FCC has a mild acid taste and has the lowest irritation potential.



USES and APPLICATIONS of PURAC FCC:
Pharmaceutical technology uses Purac FCC to convert water-insoluble medicinal substances into salts of lactic acid (lactates); these are more soluble in water (example: ciprofloxacin).
In cosmetics, Purac FCC is used in skin creams and other products to treat acne.


Purac FCC is used to make cultured dairy products, as a food preservative, and to make chemicals.
Purac FCC has a role as a Daphnia magna metabolite and an algal metabolite.
Purac FCC is functionally related to a propionic acid.


Purac FCC is a conjugate acid of a lactate.
A normal intermediate in the fermentation (oxidation, metabolism) of sugar.
The concentrated form is used internally to prevent gastrointestinal fermentation.


Sodium lactate is the sodium salt of Purac FCC, and has a mild saline taste.
It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the resulting Purac FCC to create a compound having the formula NaC3H5O3.
Purac FCC was one of active ingredients in Phexxi, a non-hormonal contraceptive agent.


This results in a mild but effective exfoliation of the horny layer and in the simultaneous regeneration of cells.
Purac FCC stimulates the production of collagen and glycosaminoglycans that make up the intercellular material.
Another advantage provided by Purac FCC is that it naturally hydrates the skin; this action results in increased formation of ceramides, thus enhancing the function of the keratin barrier.


Within the Personal Care sector, Purac FCC functions as an acidifier with moisturising, exfoliating and antibacterial properties.
When used topically, Purac FCC can assist with the removal of dead skin cells helping to renew the skin, improve skin texture and tone along with functioning as a humectant.


The casein in fermented milk is coagulated (curdled) by Purac FCC.
Purac FCC is produced natutally in the Lacto-fermentation of foods.
Some examples of these types of foods are Kimchi, Sauerkraut, sour beer, tsukemono, suan cai, atsara and yoghurt.


Purac FCC is used directly as the acidulant.
Pickled Vegetables uses of Purac FCC: Purac FCC is effective in preventing the spoilage of olives, gherkins, pearl onions and other vegetables preserved in brine.


Purac FCC is a vital ingredient in Ricotta Impastata, Mozzarella, Queso Blanco and other speciality cheeses and can be used in the production of sour milk products, such as Koumiss, Laban, Kefir, as well as some cottage cheeses.
Purac FCC is an Alpha Hydroxy Acid (AHA) and can be used to promote higher rates of desquamation and cell renewal.


Purac FCC can be used to adjust the pH of many formulations and can be used as a milder alternative to glycolic acid.
Purac FCC and its salt, Sodium Lactate, can be used as humectants.
Purac FCC is used in facial products and also body lotions and moisturisers, never directly on skin.


Purac FCC is also used as an acidifying agent.
Purac FCC is food grade and is used for the production of several types of cheeses.
Purac FCC is particularly useful when UHT, ultra-pasturized or powdered milk are used as the starting materials, since the heat treatments used in the production of these milks deactivates the lactose and prevents the cheese culture from being able to turn it fully into Purac FCC.


Confectionery products uses of Purac FCC: such as hard boiled candy, fruit gums with Purac FCC results in a mild acid taste, improved quality and longer shelf life.
Purac FCC has moistening effect as a result of its properties to bind water in upper layers of the epidermis.


Purac FCC is used to make cultured dairy products, as a food preservative, and to make chemicals.
Purac FCC is used as a solvent and acidulant in the production of foods, drugs, and dyes.
Purac FCC is also used as a mordant in woolen goods printing, a soldering flux, a dehairing agent, and a catalyst for phenolic resins.


In production, Purac FCC is usually added so that the pH of the milk reaches around 5.0.
The casein in fermented milk is coagulated (curdled) by Purac FCC and it is also responsible for the sour flavour of sourdough breads.
Purac FCC is mainly used to adjust the pH of cosmetic products and is added during the production of shampoos to increase the shine of the hair.


Purac FCC is easy to use in liquid form.
Purac FCC works well with hyaluronic acid and Vitamins A, B and C.
Purac FCC can also be used as a pH regulator: Purac FCC will lower the pH.


Purac FCC is used Soapmaking pH adjustment, increased firmness of bars and solid format products (especially if pre-neutralised with Lye).
Purac FCC is used to produce serial products or widely used in food, vintage, beverage, drugs, polymerization, textile, leather, tobacco, feed, plastic chemicals, pesticide, polymer solution and other industry.


Purac FCC is also recommended for body and scalp-care for it helps in case of dry skin as well as skin exfoliation and cornification.
Purac FCC has been used in the production of beer for decades, contributing a unique tartness to this popular beverage.
With its 80% concentration of Purac FCC, this specially formulated solution allows you to easily control the level of tartness in your product.


Whether you’re using Purac FCC to adjust the flavour of your beer or in other food production needs, Purac FCC is the perfect choice for creating a finished product that meets all quality standards while delighting consumers.
Purac FCC can be used to adjust the pH of many formulations and can be used as a milder alternative to glycolic acid.


Purac FCC is used to adjust the pH of cosmetic products
When making shampoos, Purac FCC is added to make the hair shiner
Often used as food or feed additives, Purac FCC can improve the flavor of food and prolong the shelf life.


Purac FCC is widely used in canned food, bread, flour, pastry, feed and other industries as a food flavor improver.
Purac FCC is especially suitable for the acidity adjustment of various solid and powdered foods.
Purac FCC's excellent pH adjustment function and antibacterial ability can effectively inhibit the growth of microorganisms and prolong the shelf life of food.


Purac FCC is used Skin care (Facial care, Facial cleansing, Body care, Baby care) Hair care (Shampoos, Conditioners & Styling)
Purac FCC is a natural L-lactic acid, which is produced by fermentation from sugar.
Purac FCC has a mild acid taste and is widely used as an acidulant in the food industry.


Purac FCC has a mild acid taste and is widely used as an acidulant in the food industry.
Purac FCC is naturally present in the hair, produces a glossy, attractive appearance and is used as a pH-regulator in all kinds of hair care formulations.
In anti-acne products, Purac FCC is used for its antimicrobial action.


The cosmetics with Purac FCC should be used with the utmost care for dry complexion.
Purac FCC regulates cellular skin regeneration, and improves skin structure and colour.
Purac FCC enhances the effects of other cosmetic preparations.


Purac FCC improves skin moistening for the skin becomes more soft and elastic.
Purac FCC influences the production of skin collagen by increasing thickness and strengthening the dermis.
Purac FCC increases the level of glycosaminoglycans that is compounds that absorb water as a sponge and provide hydration of deeper layers of the skin.


Purac FCC is classed as an advanced skincare ingredient and should not be used unless you understand the usage and applications of Lactic Acid.
Purac FCC is used acne Treatments & Skin Peels, Bee Keeping, In food production, To Extend shelf life of Meat,Fish & Poultry, Acidity regulator in drinks, In dairy products, Baking, Detergent, Animal Nutrition Supplement, and General Industry.


Purac FCC is widely used as an acidulent in the food industry, as well as for preservation and flavouring.
Purac FCC is used very useful to rejuvenate the skin by encouraging the shedding of old surface skin cells.
Purac FCC can reduce the appearance of fine lines, irregular pigmentation, age spots & decreases enlarged pores.


Purac FCC and its salt, Sodium Lactate, can be used as humectants.
Purac FCC is used skincare pH adjustment, humectancy, skin brightening, desquamation, exfoliation.
Purac FCC is used haircare pH adjustment, humectancy.


Purac FCC has an anti-microbial effect and is the basis for preservation by fermentation in many food products.
Purac FCC serves as a preservative, pH regulator and flavouring agent.
Purac FCC is primarily found in sour milk products, such as: koumiss, leban, yogurt, kefir, and some cottage cheeses.


Faster exfoliation of cells results in the growth of new ones.
Preparations with Purac FCC support the treatment of acne.
When using masques with Purac FCC pointwise (7.0-15.0%) one can try removing sun, acne and aging maculae.


After using preparations with Purac FCC one should protect the skin against sun.
Without the layers of cornified cells, “young” epidermis absorbs nourishing cosmetics considerably better.
Therefore, tonics, scrubs and masques with Purac FCC belong to basic cosmetics for the care of oily, mixed, acne and mature complexions.


The fastest growing use for Purac FCC is its use as a monomer for the production of polylactic acid or polylactide (PLA).
Applications for PLA include containers for the food and beverage industries, films and rigid containers for packaging, and serviceware (cups, plates, utensils).


The PLA polymer can also be spun into fibers and used in apparel, fiberfill (pillows, comforters), carpet, and nonwoven applications such as wipes.
Purac FCC is used in dyeing baths, as mordant in printing woolen goods, solvent for water-insoluble dyes (alcohol-soluble induline, nigrosine, spirit-blue).


Purac FCC is often used in creams & lotions at a lower concentration for a more gentle acid-based peel.
Purac FCC is used in cosmetic to biolifting for it makes the skin elastic, evens wrinkles, brightens discolorations and narrows pores.
Purac FCC is also used in conditioners and shampoos because it activates hair bulbs, accelerating hair growth.


The combination of mild peeling, regeneration and hydration that Purac FCC offers, makes it an ideal peeling treatment for sensitive and dehydrated skin and a good choice for skin that will undergo chemical peeling for the first time.
The Purac FCC in combination with the pH result in targeted actions and indications.


Purac FCC is applied to adjust the pH of cosmetic products such as shampoo and shower gel or creams and lotions.
As Purac FCC is evident from the name, it reduces the pH of a product.
In addition to pH-regulation Purac FCC has excellent moisturizing effects.


An exception is the application in chemical peels.
Purac FCC is widely used in a range of food, industrial and manufacturing processes.
Purac FCC can be used for adjusting pH in the mash or sparge water.


Purac FCC may vary in colour from transparent to pale yellow.
Purac FCC is used a pH meter or test strips to control the pH.
Purac FCC may also be used in the final beer or wine for adding acidity.


Purac FCC is used to treat dry, rough & scaly skin.
Purac FCC may also be used for other conditions as determined by your doctor.
Normally Purac FCC is titrated with a dilute solution of Lactic Acid (10 or 20% in water) until the desired pH is achieved.


Purac FCC is used reducing chromates in mordanting wool.
Purac FCC is used manufacturing cheese, confectionery.
Purac FCC is used component of babies' milk formulas; acidulant in beverages; for acidulating worts in brewing.


Purac FCC is the natural L-Lactic acid produced by fermentation from sugar.
Purac FCC has a mild acid taste and is widely used as an acidulant in the food industry.
Purac FCC's primary functions are to preserve flavor.


Likewise, Purac FCC is used in lactofermentation and is used to preserve silages in feed production.
In technical applications, Purac FCC provides support through its biocidal effect and is therefore a component of disinfectant solutions and other cleaners.
In addition, Purac FCC is used for gentle decalcification.


It is preferred as an acidulate as Purac FCC tends to have less of a destabilizing effect on emulsions than Citric Acid.
Purac FCC is used treating dry, rough & scaly skin.
Purac FCC may also be used for other conditions as determined by your doctor.


Purac FCC is one of the popular food additives and ingredients in most countries.
Commonly Purac FCC is used as a preservative and antioxidant.
Purac FCC also has uses as a fuel additive, chemical intermediate, acidity regulator, and disinfectant.


Purac FCC is also used in dialysis solutions, which results in a lower incidence of side effects compared to Sodium Acetate which can also be used.
Purac FCC is used frequently in the cosmetic industry due to the effect of promoting collagen production, helping to firm the skin against wrinkles and sagging.


Purac FCC is used as an additive in animal nutrition.
Purac FCC has health promoting properties.
Purac FCC is used as a humectant, or moisturizer, in some cosmetics.


Purac FCC ia used as a mordant, a chemical that helps fabrics accept dyes, in textiles.
Purac FCC is also used in tanning leather.
Purac FCC is used in the manufacturing of lacquers and inks.


Purac FCC is food grade and is used for the production of several types of cheeses.
Purac FCC is particularly useful when UHT, ultra-pasteurised or powdered milk are used as the starting materials, since the heat treatments used in the production of these milks deactivates the lactose and prevents the cheese culture from being able to turn it fully into Purac FCC.


The inclusion of additional Purac FCC prior to rennetting overcomes this shortage and improves the curd yield.
Purac FCC is a vital ingredient in Ricotta Impastata, Mozzarella, Queso Blanco and other speciality cheeses and can be used in the production of sour milk products, such as Koumiss, Laban, Kefir, as well as some cottage cheeses.


Purac FCC is the principal building block for Poly Lactic Acid (PLA).
PLA is a biobased and bio-degradable polymer that can be used for producing renewable and compostable plastics.
Purac FCC is used to adjust the pH of the mash or the sparge water.


Purac FCC is used for Pilsner style lagers to reduce alkalinity.
Purac FCC used to reduce alkalinity without adding sulphate and chloride ions.
Purac FCC can also be used for minor corrections in brewing


Purac FCC can also cause micro peeling, which can help reduce various scars and age spots.
This is a great solution for people with sensitive or dry skin where exfoliants don’t work.
Purac FCC is used to treat dry, rough & scaly skin.


Purac FCC may also be used for other conditions as determined by your doctor.
Dilute Purac FCC before use.
As with all of the acids, Purac FCC is important to let your skin acclimate to their use.


For those whose skin is not used to the acids a slight stinging and redness may result.
If this occurs, Purac FCC reduce usage.
Purac FCC contains an alpha hydroxy acid (AHA) that may increase your skin's sensitivity to the sun and particularly the possibility of sunburn.


Purac FCC is used a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards.
Purac FCC reduces the alkalinity levels of brewing liquor stimulating maximum enzyme activity in the wort enabling optimum pH levels throughout the whole brewing process.


Purac FCC is used as a valuable component in biomaterials.
Purac FCC is used as a natural anti-bacterial agent in disinfecting products.
Purac FCC is used in the industrial processes.


PH can be used at higher levels for beer souring.
Purac FCC has a good moisturising effect on the skin and can be used in water based serums, gels, toners, creams and lotions.
Purac FCC can help the skin to look fresher and younger.


Purac FCC is especially beneficial in night creams and anti aging products.
When Purac FCC is used at higher concentrations, it can have an exfoliating effect.
Purac FCC will improve the skin's appearance and help to remove surface debris and dead skin cells.


Hair Care: Used in a hair pack, Purac FCC will cleanse a congested scalp for example, after a weave has been removed, having been on for several months.
Never use Purac FCC directly on the skin.


Best Purac FCC is added in stage 3 (cool down) when making creams and lotions.
Be aware that Purac FCC can make creams and lotions thinner or unstable so you need to start with a very strong and stable cream or lotion.
As a pH regulator, Purac FCC can be used to move the pH number lower (more acidic) for when using Preservative K which only functions correctly in a narrow pH range.


Often, Purac FCC is derived from milk, however, ours is made from maize or corn, and free from GMO.
Purac FCC is sold at an 80% concentration i.e. Purac FCC with 20% Water as an aqueous solution.
According to the Cosmetic Ingredient Database (CosIng), the functions of Purac FCC are: Buffering, Humectant, Skin Conditioning.


Purac FCC improves extract yield and fermentation ability
Purac FCC is suitable for beers where no other anions are needed for example lagers.
Purac FCC improves clarity and stability of the finished product.


Purac FCC concentration for chemical exfoliation, suitable for all skin types.
Purac FCC offers cellular regeneration, hydration and reduction of the appearance of wrinkles on the skin.
Typical use level of Purac FCC is between 1-20% in peels, creams, lotions, masks, cleansers.


Due to Purac FCC's acidity the final product needs to be tested for safe pH.
Optimal pH range of Purac FCC is from 3.5-5.0.
Some over the counter products, after adding Purac FCC, will separate as a result of the low pH, and need to be stabilized.


In many food products usually serves, Purac FCC is used as either as a pH regulator, as a preservative, or as a flavoring agent.
Purac FCC is used as an acidity regulator.
Purac FCC is effective in preventing the spoilage of vegetabels.


Purac FCC is often used as a milder alternative to glycolic acid in cosmetic formulations and can also be used to lower pH during manufacturing.
Purac FCC is produced by fermentation of glucose syrup from maize by using a bacterial strain.
Purac FCC is an acid and should never be used undiluted.


When used in proper concentrations (up to 5.0%), Purac FCC loosens intercellular cement.
Regular use of cosmetics with Purac FCC rejuvenates the epidermis and makes wrinkles even by means of a gradual exfoliation of dead cells of horny layer.


Purac FCC makes small surface wrinkles even and improves skin elasticity as well as firmness; it is an anti-aging ingredient; it helps in case of discolorations and small acne scars.
Purac FCC makes pores clear and shows antibacterial properties, hence, it prevents the creation of trouble spots that are all kinds of eczemas and blackheads; it helps in the treatment of acne.


Purac FCC is used soapmaking pH adjustment, increased firmness of bars and solid format products (especially if pre-neutralised with Lye).
Purac FCC is used Skincare pH adjustment, humectancy, skin brightening, desquamation, exfoliation.
Purac FCC is used Haircare pH adjustment, humectancy.


Skin Care: Depending on the strength of the dilution used, Purac FCC can be used as a pH regulator, a moisturiser or as a skin peel.
In the lower percentages, Purac FCC reduces Trans Epidermal Water Loss (TEWL) by supporting the skin's barrier function.
When applied, Purac FCC cleaves the bonds between keratinocytes on the external layer, thus reducing them and leading to gradual regeneration.


Purac FCC is also used in leather tanning, oil well acidizing, and as a plant growth regulator.
Purac FCC is applied in Petroleum Production and Refining, Soldering, Farming (Pesticides) ,Leather Tanning and Processing, Fur Dressing and Dyeing, Textiles (Printing, Dyeing, or Finishing).


Purac FCC is used as an excellent acidification agent for many dairy products.
Purac FCC is used as an enhance savory flavors.
In pharmaceutical technology, Purac FCC is used as a starting material for other substances.


Purac FCC is used in preparation of sodium lactate injections. Ingredient of cosmetics.
Purac FCC is used component of spermatocidal jellies.
Purac FCC is used for removing Clostridium butyricum in manufacturing of yeast; dehairing, plumping, and decalcifying hides.


Purac FCC is used solvent for cellulose formate.
Purac FCC is used flux for soft solder.
Purac FCC is used manufacturing lactates which are used in food products, in medicine, and as solvents.


Purac FCC is used plasticizer, catalyst in the casting of phenolaldehyde resins.
Purac FCC can be used as acidulent, flavoring agent and pH regulator in beverages, meat, sourdough, salads and dressings, confectionery and pickled vegetables.


Purac FCC is used in food and technical applications.
Liquid Purac FCC, as a 1:1 mixture of levorotatory and dextrorotatory lactic acid, is very commonly used for acid regulation in bakery and confectionery products or in beverages and for preservation.


-Material uses of Purac FCC:
Purac FCC is the monomer of polylactides or polylactic acids (PLA), which are used in various ways as biodegradable and biobased plastics.
Purac FCC has an antibacterial effect and is therefore added to liquid soaps, cleaners and detergents.

They develop their disinfecting effect optimally at a pH value of 3 to 4.
Purac FCC was and is also used as a contraceptive.
Purac FCC is used as a descaling agent in the tannery for descaling hides.

Purac FCC is also used for this purpose in the textile industry and printing companies.
Some cleaning tablets for coffee machines, soft drinks machines and similar appliances contain Purac FCC as a descaling agent.
Beekeepers use Purac FCC to treat bees against the Varroa mite, ensuring that the treated hives or honeycombs are brood free.
Arachnologists use Purac FCC to illuminate the prepared epigyne of female spiders or other chitin structures and to dissolve tissue debris.


-Beer brewing uses of Purac FCC:
Purac FCC is to lower the pH and add a bit of tartness.
Naturally add in small amounts or Purac FCC will become quite sour.


-Cheese making & Whipped Butter uses of Purac FCC:
Ricotta in particular and whipped butter in combination with GDL.
Ricotta Impastata, Mozzarella and Queso Blanco.


-Interesting non food uses for Purac FCC:
Purac FCC is the principal building block for Poly Lactic Acid (PLA) biodegradable plastics.
PLA is a biobased and bio-degradable polymer that can be used for producing renewable and compostable plastics.
Purac FCC is also being used in the cosmetics industry for acne treatment.


-Power supply uses of Purac FCC:
A number of foods are made directly through Purac FCC fermentation.
This mainly includes sour milk products such as sour milk, yogurt, kefir and buttermilk.
These are produced by infecting pasteurized milk with starter cultures of Purac FCC bacteria.

Other products include lacto-fermented vegetables such as sauerkraut, beetroot in some varieties of borscht, or kimchi, as well as sourdough and sourdough products.
Silage, fresh feed made sustainable by fermentation, is also based on Purac FCC fermentation.
As a food additive, Purac FCC carries the designation E 270.

Purac FCC is used in many different ways as an acidity regulator in the food and luxury goods industries, for example in baked goods, confectionery and occasionally in lemonades.
By changing the pH value in the food to a pH of about 4, the food is preserved, since colonization with other microorganisms is largely excluded.
In the form of the salts calcium lactate or calcium lactate gluconate Purac FCC can also be added for calcium enrichment.



CLAIMS OF PURAC FCC:
*Anti-acne Agents
*Antimicrobials
*Moisturizing Agents



FUNCTIONS OF PURAC FCC:
*In food, apart from its nutritional function for normal growth, Purac FCC improves flavor and taste, improves quality of food and beverage products such as confectionery, cake, milk powder, yogurt etc. as firming agent, buffering agent and flour regulator.
*Purac FCC increases effectiveness of antioxidants, prevents decolorization of fruits and vegetables.



FEATURES AND BENEFITS OF PURAC FCC:
*Purac FCC is very useful to rejuvenate the skin by encouraging the shedding of old surface skin cells
*Purac FCC can reduce the appearance of fine lines, irregular pigmentation, age spots & decreases enlarged pores
*Purac FCC is used good choice for first-time peel users or for those with sensitive skin
*Purac FCC is often used in creams & lotions at a lower concentration for a more gentle acid-based peel.



USE IN FOOD, PURAC FCC:
Purac FCC is a natural preservative found in several foods, including pickled vegetables, yoghurt, and baked goods.
Purac FCC is a cheap and minimally processed
Lactobacillus and Streptococcus cultures produce Purac FCC through fermentation.
The bacteria break down sugar to extract energy and produce Purac FCC as a byproduct.
Purac FCC helps regulate pH levels and prevents the growth of microorganisms, extending shelf life.



HOW TO USE PURAC FCC IN COSMETICS:
- Purac FCC is a product that does not apply to pure skin
- Purac FCC can be included as an ingredient in cosmetic compositions containing acidulant and water: serums, gels, tonics, masks, lotions, creams, shampoos, cleanses, etc.



BENEFITS AND APPLICATIONS OF PURAC FCC:
Purac FCC is used to treat hyperpigmentation, age spots, and other conditions that contribute to a dull, uneven complexion.
Purac FCC also enhances skin tone and minimises the appearance of pores.

Purac FCC promotes cell turnover and cell renewal, which are the processes through which your skin loses old cells and replaces them with new ones.
Purac FCC works really well for sensitive skin because of its milder nature as compared to other alpha-hydroxy acids.

Purac FCC is also a key component of over-the-counter lotions and creams for "chicken skin," i.e., pimples on the backs of the arms.
Purac FCC aids in the dissolution of the clog of skin cells that form around the hair follicle, smoothing out the bumpiness.
Purac FCC is commonly found in topical therapies for eczema, psoriasis, and rosacea.



THE PROPERTIES OF PURAC FCC:
The properties of Purac FCC
- Keratolytic exfoliates the skin by removing dead skin and scalp cells
- Stimulates collagen and elastin synthesis, promoting cell renewal
- Purac FCC improves skin grain and appearance pH
- Activates the emulsifier conditioner used in the manufacture of hair care compositions



BENEFITS OF PURAC FCC:
*Brightens a dull complexion
*Humectant and skin firmer
*Exfoliant
*Improves skin tone and texture
*Vegan Friendly
*GMO-free



FUNCTION OF PURAC FCC:
In food, apart from its nutritional function for normal growth, Purac FCC improves flavor and taste, improves quality of food and beverage products such as confectionery, cake, milk powder, yogurt etc. as firming agent, buffering agent and flour regulator.
Purac FCC increases effectiveness of antioxidants, prevents decolorization of fruits and vegetables.



BENEFITS OF PURAC FCC:
Purac FCC reduces the alkalinity levels of brewing liquor, stimulating maximum enzyme activity in the wort enabling optimum pH levels throughout the whole brewing process.
Purac FCC improves extract yield and fermentability.
Purac FCC is suitable for beers where no other anions are needed, for example, pilsner lagers.
Purac FCC can also be used to reduce the pH of final wort or products.



SUGGESTED BLENDS OF PURAC FCC:
Purac FCC works well in conjunction with Vitamin A, B and C.
Be sure to check the final pH level is not less than 3.5 when combining several acidic ingredients together.



HOW PURAC FCC WORKS:
Purac FCC works by removing the upper layer of skin cells, which is usually composed of dead skin cells.
Purac FCC also works by increasing the natural moisture retention capabilities of the skin to give your skin a hydrated look.



CONCENTRATION AND SOLUBILITY OF PURAC FCC:
Purac FCC is recommended that it should be used at a concentration of 1–5%.
Purac FCC is soluble in water, alcohol, and glycerol but is insoluble in oil.



HOW TO USE PURAC FCC:
Prepare the oil and water phases of your formulation separately.
Heat the oil and water phases using a double boiler.
Add Purac FCC to the water phase, accompanied by constant stirring.
Blend both the phases together using a mini-mixer or a large mixing brush



PHYSICAL and CHEMICAL PROPERTIES of PURAC FCC:
End Use: Food additive
Color: yellow, Clear, Colorless
Odor: Characteristic
pH: < 1.2 @ 25 °C (77 °F)
Boiling Point: 120 - 130 °C (248 - 266 °F)
Flash Point: Not applicable
Auto-ignition Temperature: > 400 °C (> 752 °F)
Viscosity, Dynamic: 5 - 60 mPa.s @ 25 °C (77 °F)
Supplier: Purac America Inc
CAS: 79-33-4
Applications: Flavor, Additive Preservative
Chemical Form: Liquid
Product: L-Lactic acid
Form: liquid
Grade: edible special

Color: fresh max. 50 apha
Color, 6 months, 25°C max. 50 apha
Odor: agreeable
Stereochemical purity (L-isomer): min. 95%
Assay: 87.5-88.5% w/w
Density: at 20°C 1.20-1.22 g/ml
Sulphated ash max.: 0.1%
Heavy metals total max.: 10 ppm
Iron max.: 10 ppm
Arsenic max.: 1 ppm
Calcium max.: 20 ppm
Chloride max.: 10 ppm
Sulphate max.: 20 ppm
Reducing sugars: passes test FCC
Molecular formula: CH3CHOHCOOH
Molecular weight: 90
Chemical name: 2-hydroxypropionic acid

Odor: odorless
Melting point/freezing point:
Melting point: 18 °C at 1.013 hPa
Initial boiling point and boiling range: 122 °C at 18,66 - 19,99 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 113 °C - closed cup
Autoignition temperature: 400 °C at 1.011,4 - 1.018,9 hPa
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 100 g/l at 20 °C - soluble

Partition coefficient: n-octanol/water:
log Pow: ca.-0,54 at 25 °C - Bioaccumulation is not expected.
Vapor pressure: No data available
Density: 1,25 g/cm3 at 15 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Surface tension 70,7 mN/m at 1g/l at 20 °C
Formula: H₃CCH(OH)COOH
MW: 90.08 g/mol
Boiling Pt: 122 °C (20 hPa)
Density: 1.11…1.21 g/cm³ (20 °C)
Storage Temperature: Ambient
MDL Number: MFCD00004520
CAS Number: 50-21-5
EINECS: 200-018-0

CAS: 50-21-5
MF: C3H6O3
MW: 90.08
EINECS: 200-018-0
Mol File: 50-21-5.mol
Lactic acid Chemical Properties
Melting point: 18°C
alpha: -0.05 º (c= neat 25 ºC)
Boiling point: 122 °C/15 mmHg (lit.)
density: 1.209 g/mL at 25 °C (lit.)
vapor density: 0.62 (vs air)
vapor pressure: 19 mm of Hg (@ 20°C)
FEMA: 2611 | LACTIC ACID
refractive index: n20/D 1.4262

Fp: >230 °F
storage temp.: 2-8°C
solubility: Miscible with water and with ethanol (96 per cent).
form: syrup
pka: 3.08(at 100℃)
Specific Gravity: 1.209
color: Colorless to yellow
Water Solubility: SOLUBLE
Merck: 145,336
JECFA Number: 930
BRN: 1209341
Stability: Stable.
Physical state: viscous
Color: colorless



FIRST AID MEASURES of PURAC FCC:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person. Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of PURAC FCC:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of PURAC FCC:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of PURAC FCC:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of PURAC FCC:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of PURAC FCC:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available

Pure Pure Tung Oil, also known as China wood oil, is a drying oil obtained by pressing the seeds of the tung tree (Vernicia fordii or Vernicia montana).
Chemically, Pure Tung Oil is composed primarily of triglycerides with high levels of unsaturated fatty acids, particularly α-eleostearic acid.
When exposed to air, these unsaturated fatty acids undergo a process called polymerization, forming a durable, water-resistant finish.

CAS Number: 8001-20-5
EC Number: 232-272-4

China wood oil, Nut oil, Tung tree oil, Wood oil, Aleurites oil, Tungseed oil, Oiticica oil, Eucya oil, Kalo oil, Varnish tree oil, Hsiang oil, Lumbang oil, Orelia oil, Thitkado oil, Tung nut oil, Kohayu oil, Pinnay oil, Varnish tree seed oil, Dreschlera triseptata oil, Tracheostoma yedoense oil, Chieh oil, Hokkaung oil, Tung-shu oil, Tung-yu oil, Noog oil, Wood-oil tree oil, Tung-lu oil, Chinese nut oil, Wood-oil oil, Orangewood oil, Tung shu oil, Ta-kai oil, I-chiu oil, Ho-t'ung oil, Hok Pure Tung Oil, Kina-Pure Tung Oil, Kio-oil, Leguminous oil, Nut-oil tree oil, Orelia galactodendron oil, Perilla oil, Tung-shu tree oil, Tung-yu tree oil, Tungtze oil, Lumbang tree oil, Borneo bean oil, Chinezenootolie, Kala oil, Poochay oil, Varnish tree nut oil, Fuegaoil, Kape-mayapis oil, Kalumpang oil, Aleurites oil tree oil, Japan wood oil



APPLICATIONS


Pure Tung Oil finds widespread use as a finish for wooden furniture, providing both protection and enhancing its natural beauty.
Pure Tung Oil is commonly used to seal and protect hardwood floors, offering durability and resistance to foot traffic.

Pure Tung Oil is favored for finishing kitchen countertops and cutting boards due to its food-safe properties.
Wooden decks and outdoor furniture benefit from Pure Tung Oil's ability to withstand weathering and UV exposure.

In the realm of musical instruments, Pure Tung Oil is often used to finish guitar bodies and other wooden components.
Pure Tung Oil serves as a key ingredient in the formulation of varnishes and wood sealers, providing a glossy, protective coat.
Traditional Chinese medicine utilizes Pure Tung Oil for its purported therapeutic properties, such as promoting hair growth and relieving joint pain.

Pure Tung Oil is employed in the production of linoleum, where it acts as a binder for the natural materials.
Pure Tung Oil is used in the creation of handcrafted wooden bowls and utensils, ensuring a safe and durable finish.

Pure Tung Oil is utilized in the restoration and preservation of historical wooden structures and artifacts.
Woodturners and woodworkers apply Pure Tung Oil to lathe-turned projects, enhancing the wood's natural grain patterns.

Pure Tung Oil serves as a base for mixing pigment in oil painting, providing a glossy finish to artwork.
Pure Tung Oil is used to coat outdoor fences and railings, protecting them from moisture and rot.
Boat builders rely on Pure Tung Oil to seal and protect wooden hulls and decks against marine elements.

Pure Tung Oil is applied to wooden toys and children's furniture, ensuring a safe and non-toxic finish.
Pure Tung Oil is used in the manufacturing of high-quality wooden flooring, providing both beauty and durability.
Wood carvers use Pure Tung Oil to finish their creations, accentuating intricate details and textures.
Pure Tung Oil is applied to wooden tool handles to improve grip and protect against wear and tear.

Pure Tung Oil serves as a natural alternative to synthetic wood finishes, appealing to environmentally conscious consumers.
Pure Tung Oil is used in the production of fine cabinetry and woodworking, where its rich finish adds value and elegance.
Artisans apply Pure Tung Oil to decorative wooden objects, such as picture frames and sculptures, for a timeless finish.

Pure Tung Oil is utilized in the construction of outdoor pergolas and trellises, enhancing the wood's natural beauty.
Pure Tung Oil is used in the restoration of antique wooden furniture, reviving its luster and beauty.

Pure Tung Oil serves as a protective coating for exterior wooden siding, maintaining its appearance and integrity.
Pure Tung Oil is applied to wooden doors and windows to protect against moisture infiltration and warping.

Pure Tung Oil is used in the crafting of decorative wooden bowls, plates, and other kitchenware, adding both beauty and functionality.
Woodworkers apply Pure Tung Oil to turned pens and pencils, providing a smooth, durable finish.
Pure Tung Oil is utilized in the construction of outdoor gazebos and pergolas, offering protection against weathering and decay.

Pure Tung Oil serves as a sealant for wooden window frames and sills, prolonging their lifespan and enhancing their appearance.
Pure Tung Oil is used in the manufacturing of fine wooden musical instruments, such as violins and cellos, for its resonance and protective qualities.
Woodcarvers apply Pure Tung Oil to intricate carvings, preserving the wood's natural color and grain while adding depth to the details.
Pure Tung Oil is employed in the restoration of historic wooden ships and boats, ensuring authenticity and longevity.

Pure Tung Oil is used to finish wooden flooring in high-traffic areas such as commercial spaces and public buildings, providing a durable and long-lasting surface.
Pure Tung Oil is applied to outdoor wooden sculptures and art installations, protecting them from the elements while allowing the wood to breathe.

Pure Tung Oil is used in the crafting of traditional Japanese shoji screens and doors, imparting a warm, natural finish.
Pure Tung Oil is applied to wooden picture frames and mirrors, enhancing their appearance and protecting them from damage.
Woodworkers use Pure Tung Oil as a finish for custom-built cabinetry and built-in shelving, ensuring a high-quality, long-lasting result.
Pure Tung Oil is applied to wooden garden furniture and planters, protecting them from moisture and extending their lifespan.

Pure Tung Oil serves as a finish for wooden staircases and handrails, providing both safety and aesthetic appeal.
Pure Tung Oil is used in the production of luxury wooden watches and accessories, adding a touch of sophistication and durability.
Artisans apply Pure Tung Oil to turned bowls and vases, highlighting the natural beauty of the wood grain.
Pure Tung Oil is used in the construction of outdoor wooden structures such as pergolas, arbors, and trellises, providing protection from the elements.

Pure Tung Oil serves as a protective coating for wooden outdoor sculptures and carvings, preserving their beauty for years to come.
Pure Tung Oil is applied to wooden cutting boards and serving trays, providing a safe and durable surface for food preparation and presentation.

Woodworkers use Pure Tung Oil to finish custom-built doors and windows, enhancing their appearance and protecting them from the elements.
Pure Tung Oil is applied to wooden garden sheds and outbuildings, providing protection from moisture and weathering.

Pure Tung Oil is used in the restoration of antique wooden furniture, reviving its beauty and preserving its historical value.
Pure Tung Oil serves as a finish for custom-made wooden furniture, providing a durable and attractive surface.

Woodworkers apply Pure Tung Oil to turned bowls and platters, enhancing the wood's natural beauty and durability.
Pure Tung Oil is used in the crafting of decorative wooden boxes and chests, providing both beauty and protection for treasured items.



DESCRIPTION


Pure Pure Tung Oil, also known as China wood oil, is a drying oil obtained by pressing the seeds of the tung tree (Vernicia fordii or Vernicia montana).
Chemically, Pure Tung Oil is composed primarily of triglycerides with high levels of unsaturated fatty acids, particularly α-eleostearic acid.
When exposed to air, these unsaturated fatty acids undergo a process called polymerization, forming a durable, water-resistant finish.

Pure Pure Tung Oil is often used as a finish for woodwork and as a component in various coatings and paints.
It's valued for its ability to enhance the natural beauty of wood while providing protection against moisture and wear.

Pure Tung Oil, derived from the seeds of the tung tree, boasts a rich history dating back centuries.
Pure Tung Oil possesses a golden-yellow hue, exuding warmth and depth.
Pure Tung Oil is renowned for its remarkable ability to penetrate deep into wood fibers, enhancing its natural grain and color.

When applied, Pure Tung Oil creates a lustrous finish that accentuates the beauty of wood surfaces.
One of its notable qualities is its resistance to water, making it an excellent choice for outdoor furniture and marine applications.

Pure Tung Oil dries to a durable, hard finish, offering protection against scratches, stains, and UV damage.
Unlike some synthetic finishes, Pure Tung Oil maintains the natural look and feel of wood, adding character and charm.

Its versatility extends beyond woodworking, finding applications in varnishes, sealers, and traditional Chinese medicine.
Pure Tung Oil has a distinctive nutty aroma, which diminishes as it cures, leaving behind a faint, pleasant scent.
Craftsmen appreciate Pure Tung Oil for its ease of application, requiring simple techniques such as wiping or brushing.

As a renewable resource, Pure Tung Oil is environmentally friendly, promoting sustainable practices in woodworking and coatings industries.
Pure Tung Oil's low viscosity allows it to flow smoothly, ensuring even coverage and a uniform finish.

With proper care and maintenance, Pure Tung Oil finishes can withstand the test of time, aging gracefully while retaining their beauty.
Its natural drying process eliminates the need for harsh chemicals or additives, reducing environmental impact.

Pure Tung Oil's inherent flexibility allows it to expand and contract with wood, minimizing the risk of cracking or peeling.
When cured, Pure Tung Oil forms a protective barrier that resists moisture, mold, and mildew, ideal for humid climates.

Its non-toxic nature makes Pure Tung Oil a safe choice for interior applications, suitable for furniture, countertops, and wooden toys.
Pure Tung Oil finishes can be easily rejuvenated with periodic maintenance, ensuring lasting beauty and protection.

Artists appreciate Pure Tung Oil as a medium for mixing pigments, creating vibrant colors and textured effects on canvas.
Pure Tung Oil's drying time varies depending on conditions, typically ranging from a few hours to several days for a full cure.
Its high resistance to chemicals and solvents makes Pure Tung Oil an excellent choice for industrial coatings and finishes.

Pure Tung Oil's glossy sheen adds a touch of elegance to any woodworking project, from flooring to cabinetry.
The natural translucency of Pure Tung Oil allows it to enhance the wood's natural characteristics, rather than masking them.

Pure Tung Oil's durability and longevity make it a wise investment for homeowners seeking quality finishes that stand the test of time.
From ancient traditions to modern applications, Pure Tung Oil continues to be valued for its beauty, versatility, and enduring quality.



PROPERTIES


Density: 0.937 g/ml at 25°C
Refractive index (nD): 1.52 (20°C)
Flash point: >110°C
Storage temp.: 2-8°C
Color Gardner: ≤12



FIRST AID


Inhalation:

Move to Fresh Air:
If exposed to Pure Tung Oil fumes or vapors, immediately move the affected person to an area with fresh air.

Seek Medical Attention:
If the person experiences difficulty breathing or shows signs of respiratory distress, seek medical attention promptly.

Provide Oxygen:
If available and trained to do so, administer oxygen to the affected person while awaiting medical assistance.


Skin Contact:

Remove Contaminated Clothing:
If Pure Tung Oil comes into contact with the skin, promptly remove any contaminated clothing.

Wash Skin Thoroughly:
Wash the affected area with soap and water for at least 15 minutes, ensuring thorough rinsing to remove any traces of Pure Tung Oil.

Use Mild Soap:
Use a mild soap or detergent to gently cleanse the skin, avoiding harsh chemicals that may exacerbate irritation.

Apply Moisturizer:
After washing, apply a soothing moisturizer or emollient to the affected area to help soothe and hydrate the skin.

Seek Medical Advice:
If skin irritation persists or worsens, seek medical advice or consult a healthcare professional for further evaluation and treatment.


Eye Contact:

Flush with Water:
Immediately flush the eyes with lukewarm water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.

Remove Contact Lenses:
If wearing contact lenses, remove them as soon as possible to facilitate irrigation of the eyes.

Seek Medical Attention:
Seek immediate medical attention or contact an eye specialist if irritation, pain, or redness persists after flushing.


Ingestion:

Do Not Induce Vomiting:
Do not induce vomiting if Pure Tung Oil has been ingested, as it may lead to further complications.

Do Not Drink Water:
Refrain from giving anything by mouth to the affected person unless instructed by medical personnel.

Seek Medical Assistance:
Immediately contact a poison control center or seek medical assistance for further guidance and treatment.

Provide Information:
Provide medical personnel with details regarding the amount ingested, the time of ingestion, and any symptoms experienced by the affected person.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate personal protective equipment (PPE), including chemical-resistant gloves, safety goggles, and protective clothing, when handling Pure Tung Oil to minimize skin and eye contact.

Ventilation:
Ensure adequate ventilation in the working area to prevent the buildup of vapors.
Use local exhaust ventilation or work in well-ventilated areas to minimize inhalation exposure.

Avoid Contact:
Avoid direct contact with Pure Tung Oil.
In case of skin contact, promptly wash affected areas with soap and water.
In case of eye contact, flush eyes with water for at least 15 minutes and seek medical attention if irritation persists.

Spills and Leaks:
Clean up spills and leaks promptly to prevent accidental exposure.
Absorb small spills with inert absorbent materials such as sand, vermiculite, or clay.
For larger spills, contain the area and dispose of the material according to local regulations.

Preventive Measures:
Implement measures to prevent accidental spills or releases, such as using spill containment trays or secondary containment systems when transferring or storing Pure Tung Oil.


Storage:

Container Selection:
Store Pure Tung Oil in containers made of chemically compatible materials, such as high-density polyethylene (HDPE) or stainless steel, to prevent chemical reactions or degradation of the container.

Sealed Containers:
Ensure that containers of Pure Tung Oil are tightly sealed when not in use to prevent evaporation and contamination.

Temperature Control:
Store Pure Tung Oil in a cool, dry place away from direct sunlight and heat sources.
Avoid exposure to extreme temperatures, as this may affect the quality and stability of the oil.

Incompatible Materials:
Keep Pure Tung Oil away from incompatible materials such as oxidizing agents, acids, and strong bases, as it may react with these substances.

Labeling:
Clearly label containers of Pure Tung Oil with appropriate warning symbols, handling instructions, and safety information to inform users about potential hazards and proper handling procedures.

Separate Storage:
Store Pure Tung Oil away from food, beverages, and animal feed to prevent accidental ingestion or contamination.

Spillage Containment:
Provide spill containment measures, such as spill trays or berms, in storage areas to contain spills and prevent environmental contamination.

Fire Safety:
Pure Tung Oil is combustible and may present a fire hazard.
Store it away from ignition sources, open flames, and heat-producing equipment.
Implement fire prevention measures, such as fire extinguishers and fire suppression systems, in storage areas.

Regulatory Compliance:
Ensure compliance with local regulations and guidelines for the storage of hazardous substances, including Pure Tung Oil.
Familiarize yourself with applicable regulations regarding storage, handling, and disposal.

Training:
Provide training to personnel involved in the handling and storage of Pure Tung Oil on proper procedures, emergency response measures, and the use of personal protective equipment.

DESCRIPTION:
Pureact GLT is a 20% active, naturally derived anionic surfactant produced from L-glutamic acid and lauric acid.
Pureact GLT is a mild surfactant that is non-irritating and readily biodegradable.
Pureact GLT produces moderate to good foam, offers a silky, soft after-feel and is effective at improving the skin mildness in surfactant formulas.

INCI name: Sodium Lauroyl Glutamate

The optimum formulating pH range for Pureact GLT is 4.0 – 10.
Pureact GLT is a COSMOS-approved, anionic surfactant that helps formulators create sustainable personal care products.
The ingredient is 100% naturally derived, readily biodegradable, and free from sulfates, 1,4 dioxane, ethylene oxide and PEG.

Pureact GLT is recommended for mild and gentle body washes, and hand and facial cleaners.
Pureact GLT additionally offers a soft after-feel.

Pureact GLT is the latest innovation to Innospec’s range of sulfate-free, vegetable-based mild surfactants.
This COSMOS approved anionic surfactant helps formulators meet market trends for sustainable personal care products.

Pureact GLT is 100% naturally derived, readily biodegradable, sulfate-free, 1,4 dioxane-free, EO-free and PEG-free.
With Pureact GLT, you can create ultra-mild body washes, hand and facial cleaners that gently cleanse while providing a luxurious experience.


SAFETY INFORMATION ABOUT PUREACT GLT:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product

DESCRIPTION:

Pureact LSR is an anionic surfactant used in personal care products as well as in household and industrial applications.
Pureact LSR is naturally derived, sulfate-free and biodegradable.
Pureact LSR is often used as a co-surfactant in cleanser formulations such as shampoos and bodywashes.



CAS NUMBER: 137-16-6

MOLECULAR FORMULA: C15H29NO3.Na

MOLECULAR WEIGHT: 294.39




DESCRIPTION:

Pureact LSR can also be used in oral care applications such as toothpastes and incorporated into syndet and combo bars.
Pureact LSR is sulphate-free, anionic surfactant with 30% active content.
Pureact LSR provides dense lather and aids foam stability.
Pureact LSR can be used in clear formulations and is stable over a wide pH range.

Pureact LSR is an ideal co-surfactant.
Pureact LSR is recommended for use in cosmetics and personal care applications.
Pureact LSR is mild to skin and hair and provides a dense, luxurious lather while leaving behind an elegant after-feel on skin and hair.
Pureact LSR provides foam stability in
formulations, even in the presence of oils and electrolytes.

Pureact LSR is also able to produce a rich, stable lather in the presence of hard water.
Pureact LSR can be used in clear formulations and is stable over a wide pH range, although for best clarity a neutral pH is recommended.
Pureact LSR has excellent compatibility with anionic, nom-ionic and cationic surfactants.
Pureact LSR is also compatible with many conditioning agents which makes it ideal for use in conditioning shampoo formulations.

Pureact LSR is an anionic surfactant raw material in liquid form and has a unique characteristic odour.
Pureact LSR finds use in many cosmetic and detergent products because it is a surfactant that creates foam and has high cleaning power.
Pureact LSR is a white powder derived from sarcosine, which make it is fate-free and biodegradable.
The surfactant is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.

Pureact LSR is personal care products as well as in household and industrial applications.
Pureact LSR is used as a co-surfactant in cleanser formulations such as shampoos and body washes.
Pureact LSR can also be used in oral care applications such as toothpastes and incorporated into syndet and combo bars.
The typical usage levels range from 1-5% on an active basis.

Pureact LSR is mild, biodegradable anionic surfactants derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products.
Pureact LSR is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
Pureact LSR is a high foam, eco-friendly surfactant.
Pureact LSR has good chlorine stability with anti-corrosion properties.

Pureact LSR has excellent ocular tolerance and gentleness.
Pureact LSR is often seen in shampoos, bath, cleansing and shaving products as a foaming agent, surfactant, and hair conditioning agent.
Pureact LSR has the ability to enhance the appearance and feel of hair by improving body, suppleness and sheen, especially in hair that is chemically damaged.
Pureact LSR also serves to clean skin and hair by mixing with oil and dirt and enabling them to be rinsed away.
As a modified fatty acid, Pureact LSR is thought to be more soluble, and have increased crystallinity and acidity compared to its original fatty acid composition.




USAGE:

Pureact LSR is used for solubilization and separation of membrane proteins and glycoprotein's; reported to inhibit hexokinase.
Pureact LSR is useful in concentrated salt solutions used in the cell lysis step during RNA purification (helps avoid excessive foaming).
Pureact LSR has been used to indicate paramagnetic anisotropy sign change in micelle mesophage.
Pureact LSR It inhibits bacterial flora of human saliva/gut at 0.25% as well as acting as a fungi static agent in aqueous dispersion (1%).


-solubilization and separation of membrane proteins
-lysis of cells during the isolation of RNA
-inhibition of hexokinase



USAGE IN COSMETIC AREA:

-Facial cleansing foam (8.52%)
-Child toothpaste (8.41%)
-Colored/highlighted hair shampoo (7.84%)
-Face cleansing gel (6.11%)
-Classic shampoo (5.89%)



APPLICATION:

-Hair cleansing
-Skin cleansing



PROPERTIES:

-Clear liquid
-80% Naturally derived
-3.0 - 11.0 Formulating pH range




FEATURES:

-Sulfate-free anionic surfactant
-providing dense lather
-aiding foam stability
-used in clear formulations
-stable over a wide pH range
-Ideal co-surfactant.



TYPICAL PROPERTIES:

-Appearance at 25°C: Clear, almost colorless liquid
-Color, APHA (100% as is): 80 maximum
-Activity %: 29-31
-Total Solids, %: 29-35
-pH (10% solution): 7.5-8.5
-Sodium Chloride, %: 0.2 maximum



SPECIFICATIONS:

-pH: 7.0-8.5
-Assay: ≥95.0%
-Appearance: White crystalline powder
-Volatility: ≤5.0%



FUNCTIONS:

-Antistatic: Reduces static electricity by neutralizing the electrical charge on a surface
-Cleaning agent: Helps keep a surface clean
-Emulsifying agent: Promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil)
-Foaming agent: Captures small bubbles of air or other gases in a small volume of liquid by changing the surface tension of the liquid
-Hair conditioner: Leaves hair easy to comb, supple, soft and shiny and/or gives volume, lightness and shine
-Skin conditioning agent: Keeps the skin in good condition
-Surfactant: Reduces the surface tension of cosmetics and contributes to the even distribution of the product during use
-Viscosity control agent: Increases or decreases the viscosity of cosmetics



CHEMICAL PROPERTIES:


-Melting point: 46 °C
-density: 1.033 g/mL at 20 °C
-vapor pressure: 0.02 hPa (20 °C)
-RTECS: MC0598960
-Fp: 267℃
-storage temp.: room temp
-solubility: H2O: 1 M at 20 °C, clear, colorless
-form: Powder
-Specific Gravity:1.03 (20/4℃)
-color: White
-Odor: at 100.00?%. bland
-PH: 7.0-9.0 (25℃, 1M in H2O)
-Water Solubility: Soluble in water (293 g/L).
-Sensitive: Hygroscopic



STORAGE:

18-25°C, dry, protect from light, sealed



SYNONYM:

N-Dodecanoylsarcosine Sodium Salt
N-Lauroylsarcosine Sodium Salt
Sodium N-Dodecanoylsarcosinate
Amin LS 30
NPAminosyl L 30As 02-30
Compound 105
Crodasinic LS 30
Crodasinic LS 30NP
N-Methyl-N-(1-oxododecyl)glycine sodium salt (1:1)
Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt (1:1)
N-Dodecanoylsarcosine Sodium Salt
Lauroylsarcosine (sodium salt)
NSC-117874
SODIUM N-LAUROYL SARCOSINATE
Sodium N-dodecanoyl-N-methylglycinate
N-Dodecanoyl-N-methylglycine sodium salt
starbld0009501
GARDOL [MI]
MEDIALAN LL-33
N-Lauroylsarcosine-S-salt
Sodium N- lauroylsarcosinate
SCHEMBL23451
C15H29NO3.Na
Lauroylsarcosine, Sodium Salt
DTXCID907066
CHEMBL1903482
C15-H29-N-O3.Na
KSAVQLQVUXSOCR-UHFFFAOYSA-M
SODIUM LAUROYL SARCOSINE 1KG
Tox21_202996
AKOS015901704
SODIUM LAUROYL SARCOSINATE
NCGC00164323-01
NCGC00260541-01
SODIUM LAUROYL SARCOSINATE
AS-81025
CAS-137-16-6
SODIUM LAUROYL SARCOSINATE
sodium;2-[dodecanoyl(methyl)amino]acetate
HY-125920
LS-178955

Purified Isophthalic Acid (PIA) is a type of isophthalic acid that has undergone a purification process to remove impurities.
Isophthalic acid itself is an organic compound with the chemical formula C8H6O4.
Purified isophthalic acid (PIA) is one of the three isomeric benzenedicarboxylic acids, the others being phthalic acid and terephthalic acid.

CAS Number: 121-91-5
EC Number: 204-506-4



APPLICATIONS


Purified isophthalic acid (PIA) is extensively used in the production of unsaturated polyester resins, contributing to the creation of durable and corrosion-resistant composite materials.
Purified isophthalic acid (PIA) plays a crucial role in the manufacturing of fiberglass-reinforced plastics, enhancing the strength and structural integrity of a variety of products.
Purified isophthalic acid (PIA) is a key ingredient in the formulation of coatings, providing enhanced adhesion, chemical resistance, and durability to painted surfaces.

In the automotive industry, PIA is utilized in the production of composite materials for various components, contributing to lightweight and fuel-efficient vehicles.
The high thermal stability of PIA makes it suitable for applications in aerospace engineering, where resistance to extreme temperatures is essential.
Purified isophthalic acid (PIA) is incorporated into the synthesis of specialty copolymers, broadening the range of materials available for specific industrial applications.
In construction materials, purified isophthalic acid contributes to the development of weather-resistant and long-lasting composites used in infrastructure projects.

Purified isophthalic acid (PIA) finds application in the formulation of adhesives, enhancing the bonding strength and chemical resistance of the final adhesive products.
Purified isophthalic acid (PIA) is employed in the creation of advanced materials for the marine industry, where its resistance to water and chemicals is highly beneficial.
In the electrical and electronics sector, Purified isophthalic acid (PIA) contributes to the development of insulating materials with improved thermal and electrical properties.

The versatility of PIA extends to its use in the production of corrosion-resistant tanks, pipes, and other equipment used in chemical processing industries.
Purified isophthalic acid (PIA) is employed in the manufacturing of certain specialty films and laminates, providing enhanced mechanical properties and durability.
Purified isophthalic acid (PIA) is used in the production of corrosion-resistant coatings for industrial equipment, ensuring longevity and reliability in harsh environments.
Purified isophthalic acid (PIA) is incorporated into the synthesis of gel coats, contributing to the smooth finish and weather resistance of surfaces in marine and automotive applications.

The chemical and thermal stability of PIA make it suitable for use in high-performance filters and membranes for industrial separation processes.
In the textile industry, PIA finds application in the production of specialty fibers with improved strength, chemical resistance, and dyeability.
Purified isophthalic acid (PIA) is utilized in the development of specialty foams and insulation materials for construction, providing enhanced thermal performance.

Purified isophthalic acid (PIA) contributes to the creation of composite materials used in sports equipment, such as lightweight and durable components for bicycles and sports gear.
In the production of decorative laminates, Purified isophthalic acid (PIA) enhances the durability and chemical resistance of the final laminated surfaces.
Purified isophthalic acid (PIA) is employed in the formulation of certain resins used in the casting and molding of intricate shapes for artistic and industrial applications.

The automotive aftermarket benefits from PIA in the production of aftermarket body panels and components that require high durability and impact resistance.
Purified isophthalic acid (PIA) is used in the manufacturing of pultruded profiles for construction, contributing to the development of lightweight and corrosion-resistant structural elements.
Purified isophthalic acid (PIA) is incorporated into specialty paints and coatings for architectural applications, providing enhanced protection against environmental factors.

Purified isophthalic acid (PIA) is utilized in the creation of composite materials for renewable energy applications, such as wind turbine components and solar panel structures.
The versatility of PIA continues to drive innovation in material science, contributing to advancements in a wide range of industrial and commercial applications.

Consumer Uses:
Purified isophthalic acid (PIA) is used in the following products:
Adhesives and sealants
Anti-freeze products
Coating products
Lubricants
Greases
Polishes and waxes

Other release to the environment of Purified isophthalic acid (PIA) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use as processing aid, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

Widespread uses by professional workers:

Purified isophthalic acid (PIA) is used in the following products: laboratory chemicals, polymers and coating products.
Purified isophthalic acid (PIA) has an industrial use resulting in manufacture of another substance (use of intermediates).
Purified isophthalic acid (PIA) is used in the following areas: formulation of mixtures and/or re-packaging.
Purified isophthalic acid (PIA) is used for the manufacture of: rubber products and .
Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Uses at industrial sites:
Purified isophthalic acid (PIA) is used in the following products: polymers, coating products, fillers, putties, plasters, modelling clay, adhesives and sealants and inks and toners.
Purified isophthalic acid (PIA) has an industrial use resulting in manufacture of another substance (use of intermediates).
Purified isophthalic acid (PIA) is used in the following areas: formulation of mixtures and/or re-packaging.
Purified isophthalic acid (PIA) is used for the manufacture of: chemicals and plastic products.
Release to the environment of this substance can occur from industrial use: for thermoplastic manufacture, as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates), in processing aids at industrial sites, manufacturing of the substance, formulation of mixtures and in the production of articles.

Purified isophthalic acid (PIA) is a key component in the production of high-quality gel coats for the surfaces of boats, providing resistance to water, UV radiation, and abrasion.
In the electronics industry, PIA contributes to the formulation of encapsulation materials and coatings, protecting sensitive electronic components from environmental factors.
Purified isophthalic acid (PIA) is utilized in the development of advanced composites for the aerospace industry, enhancing the strength-to-weight ratio of aircraft components.

Purified isophthalic acid (PIA) is incorporated into the production of specialty laminates for printed circuit boards, ensuring reliable insulation and protection.
In the automotive sector, PIA is employed in the creation of body panels, ensuring a balance of lightweight construction and structural integrity.
The chemical resistance of PIA makes it a suitable candidate for the formulation of corrosion-resistant linings for tanks and pipelines in the chemical processing industry.

Purified isophthalic acid (PIA) is used in the manufacturing of certain adhesives and sealants, providing enhanced bonding properties and resistance to environmental conditions.
Purified isophthalic acid (PIA) contributes to the development of specialty resins for 3D printing applications, where high-performance materials are required.
Purified isophthalic acid (PIA) finds application in the creation of composite materials for medical devices, ensuring biocompatibility and resistance to sterilization processes.

In the renewable energy sector, PIA is used in the production of composite materials for the blades of wind turbines, contributing to their durability and performance.
Purified isophthalic acid (PIA) is incorporated into the synthesis of specialty films used in the packaging industry, providing a combination of strength and flexibility.
Purified isophthalic acid (PIA) is employed in the formulation of corrosion-resistant coatings for steel structures in marine environments, extending their service life.

Purified isophthalic acid (PIA) plays a role in the production of specialty resins for the casting of intricate and detailed components in the arts and crafts industry.
In the medical field, Purified isophthalic acid (PIA) contributes to the development of materials for medical implants, ensuring compatibility with the human body.

Purified isophthalic acid (PIA) is utilized in the creation of specialty adhesives for the bonding of composite materials in the manufacturing of sports equipment.
The high-performance properties of PIA make it suitable for use in the production of lightweight components for the automotive racing industry.
In the construction sector, Purified isophthalic acid (PIA) is incorporated into the formulation of durable and weather-resistant coatings for architectural structures.

Purified isophthalic acid (PIA) contributes to the development of composite materials for the construction of lightweight and energy-efficient aircraft interiors.
Purified isophthalic acid (PIA) is used in the formulation of specialty resins for the production of chemical-resistant industrial flooring materials.

Purified isophthalic acid (PIA) is applied in the creation of specialty foams for insulation purposes, providing a balance of thermal performance and durability.
In the oil and gas industry, PIA is used in the formulation of coatings for offshore structures, providing protection against harsh marine conditions.
Purified isophthalic acid (PIA) is employed in the production of specialty adhesives for the assembly of electronic devices, ensuring reliable performance in challenging environments.

The high-purity characteristics of PIA make it suitable for the formulation of materials used in the semiconductor manufacturing process.
Purified isophthalic acid (PIA) is utilized in the creation of specialty resins for the casting and molding of architectural elements with intricate designs.
Purified isophthalic acid (PIA) contributes to the development of advanced materials for military applications, where strength, durability, and lightweight properties are crucial.

Purified isophthalic acid (PIA) is an essential component in the production of composite materials used in the construction of lightweight and high-strength sporting goods, such as tennis rackets and golf club components.
Purified isophthalic acid (PIA) contributes to the development of specialty adhesives for bonding materials in the aerospace industry, ensuring structural integrity and resistance to extreme conditions.
In the field of automotive manufacturing, PIA finds application in the production of durable and lightweight components, including body panels, interior parts, and structural elements.
Purified isophthalic acid (PIA) is utilized in the formulation of corrosion-resistant coatings for industrial equipment, protecting against harsh chemicals and environmental exposure.
Purified isophthalic acid (PIA) plays a role in the creation of specialized resins for the encapsulation of electronic components, providing insulation and protection against moisture and contaminants.

The chemical resistance of PIA makes it suitable for use in the formulation of specialty coatings for kitchenware and appliances, ensuring longevity and easy cleaning.
Purified isophthalic acid (PIA) is employed in the production of high-performance membranes for gas separation applications, contributing to the efficiency of separation processes in various industries.
Purified isophthalic acid (PIA) is used in the formulation of specialty inks for printing on flexible packaging materials, providing adhesion and durability.

In the manufacturing of advanced materials for military and defense applications, PIA contributes to the development of lightweight and resilient components for vehicles and equipment.
Purified isophthalic acid (PIA) is incorporated into the synthesis of specialty resins used in the creation of high-quality laminates for architectural surfaces, offering durability and aesthetic appeal.
Purified isophthalic acid (PIA) is utilized in the formulation of specialty paints for outdoor applications, contributing to the protection and longevity of structures such as bridges and pipelines.

Purified isophthalic acid (PIA) plays a role in the production of specialty foams used in the automotive and construction industries, providing insulation and impact resistance.
In the renewable energy sector, PIA is employed in the formulation of materials used in the construction of solar panel components, ensuring durability and performance.
The high thermal stability of PIA makes it suitable for use in the manufacturing of components for electrical and electronic devices that require resistance to heat.

Purified isophthalic acid (PIA) contributes to the creation of corrosion-resistant linings for tanks and vessels used in the storage and transportation of aggressive chemicals.
Purified isophthalic acid (PIA) is used in the formulation of specialty resins for the casting and molding of artistic sculptures and intricate architectural details.
In the production of specialty films for medical packaging, PIA provides a combination of barrier properties and flexibility.
Purified isophthalic acid (PIA) is incorporated into the synthesis of specialty adhesives used in the assembly of medical devices, ensuring biocompatibility and reliability.

The versatility of PIA extends to the creation of composite materials for marine applications, providing resistance to saltwater and harsh marine conditions.
Purified isophthalic acid (PIA) is employed in the formulation of specialty coatings for industrial equipment used in the food and beverage processing industry, ensuring compliance with hygiene standards.
Purified isophthalic acid (PIA) contributes to the development of advanced materials for the construction of lightweight and durable components in the automotive racing industry.
Purified isophthalic acid (PIA) is utilized in the production of specialty resins for the formulation of corrosion-resistant coatings for infrastructure in coastal environments.

In the development of specialty fibers for technical textiles, PIA enhances the strength and chemical resistance of the final textile products.
Purified isophthalic acid (PIA) is incorporated into the synthesis of specialty adhesives used in the bonding of composite materials for the production of wind turbine blades.
The high-purity characteristics of Purified isophthalic acid (PIA) make it a reliable choice in the manufacturing of high-performance materials used in critical applications across various industries.



DESCRIPTION


Purified Isophthalic Acid (PIA) is a type of isophthalic acid that has undergone a purification process to remove impurities.
Isophthalic acid itself is an organic compound with the chemical formula C8H6O4.
Purified isophthalic acid (PIA) is one of the three isomeric benzenedicarboxylic acids, the others being phthalic acid and terephthalic acid.

In purified isophthalic acid (PIA), the substance is refined to meet specific quality and purity standards, making it suitable for various industrial applications.
The purification process typically involves the removal of impurities such as colorants and other contaminants to produce a high-quality product.

Purified isophthalic acid (PIA) is commonly used in the production of resins, polymers, and fibers.
Purified isophthalic acid (PIA) is a key raw material in the manufacturing of certain types of polyesters, including unsaturated polyester resins, which find applications in the production of fiberglass-reinforced plastics, coatings, and other composite materials.
The high purity of Purified isophthalic acid (PIA) is desirable in these applications to ensure the performance and properties of the final products.

Purified isophthalic acid (PIA) is a high-quality organic compound known for its role in the production of specialty polymers.
With a molecular formula of C8H6O4, Purified isophthalic acid (PIA) belongs to the family of aromatic dicarboxylic acids.
Purified isophthalic acid (PIA) is a purified form of isophthalic acid, ensuring a high level of purity and minimal impurities.
Purified isophthalic acid (PIA) is characterized by its white crystalline appearance, reflecting its refined and purified nature.

The chemical structure of PIA consists of two carboxylic acid groups attached to a benzene ring, contributing to its versatility in polymer synthesis.
Known for its high thermal stability, purified isophthalic acid is often used in applications requiring resistance to heat and temperature fluctuations.
Purified isophthalic acid (PIA) is a key raw material in the production of unsaturated polyester resins, contributing to the development of durable and corrosion-resistant composite materials.

Purified isophthalic acid (PIA) plays a crucial role in the synthesis of certain polyesters, where its high purity is essential for achieving desired material properties.
Purified isophthalic acid (PIA) is utilized in the manufacturing of fiberglass-reinforced plastics, contributing to the strength and resilience of the final composite products.
With its excellent chemical resistance, Purified isophthalic acid (PIA) is favored in applications where exposure to various chemicals is a concern.

The refined nature of Purified isophthalic acid (PIA) makes it suitable for use in coatings, adhesives, and other applications where purity and performance are paramount.
The high-quality synthesis of Purified isophthalic acid (PIA) ensures minimal coloration, making it ideal for applications where color consistency is crucial.

As a specialty chemical, Purified isophthalic acid (PIA) finds applications in industries such as aerospace, automotive, and construction, contributing to the development of advanced materials.
Purified isophthalic acid exhibits good solubility in certain solvents, facilitating its incorporation into various formulations during material production.
Purified isophthalic acid (PIA) is known for its compatibility with other resins and additives, allowing for the formulation of customized materials with specific properties.

Purified isophthalic acid (PIA)'s versatility extends to its use as a building block in the synthesis of specialty copolymers and blends, enhancing the range of available materials.
Due to its high melting point and stability, purified isophthalic acid contributes to the dimensional stability of final polymer products.
Purified isophthalic acid (PIA)'s low volatility makes it suitable for processing at elevated temperatures without significant loss of the compound during production.
Purified isophthalic acid (PIA)'s chemical structure imparts it with a degree of rigidity, contributing to the structural integrity of polymers in which it is incorporated.

In the realm of advanced materials, purified isophthalic acid plays a crucial role in the development of lightweight and high-performance composite structures.
Its incorporation into polymeric matrices enhances the resistance of materials to environmental factors such as moisture and UV radiation.
Purified isophthalic acid (PIA) is valued for its contribution to the improvement of material properties, including mechanical strength, chemical resistance, and durability.
The refined nature of PIA ensures that it meets stringent quality standards, making it a reliable choice for critical applications in various industries.

Due to its controlled synthesis and purification processes, Purified isophthalic acid (PIA) is a consistent and dependable component in the manufacturing of specialized polymers.
As a key ingredient in the synthesis of high-performance materials, Purified isophthalic acid (PIA) continues to contribute to advancements in material science and engineering.



PROPERTIES


Chemical Formula: C8H6O4
Molecular Weight: Approximately 166.13 g/mol
Appearance: White crystalline powder
Odor: Odorless
Melting Point: Varies based on the specific grade, typically within the range of 222-235°C (432-455°F)
Boiling Point: Decomposes before boiling
Density: Varies, typically around 1.52 g/cm³
Solubility in Water: Low solubility, sparingly soluble in cold water
Solubility in Organic Solvents: Soluble in various organic solvents, including acetone and methanol
pH (1% Solution): Typically acidic
Purity: High purity due to the purification process
Hygroscopicity: Low to moderate (ability to absorb moisture from the air)
Stability: Stable under normal storage conditions
Flash Point: Not applicable (solid at room temperature)
Vapor Pressure: Negligible
Vapor Density: Not applicable (solid at room temperature)
Partition Coefficient (Log Kow): Estimated to be low due to its hydrophilic nature
Reactivity: Generally non-reactive under normal conditions
Corrosivity: Non-corrosive to metals under normal conditions
Toxicity: Low toxicity; however, ingestion or inhalation should be avoided
Flammability: Non-flammable
Autoignition Temperature: Not applicable
Decomposition Temperature: Decomposes at elevated temperatures
Biodegradability: Not readily biodegradable



FIRST AID


Inhalation:

Move to Fresh Air:
If inhaled, promptly remove the affected person to an area with fresh air.

Seek Medical Attention:
If respiratory irritation or difficulty persists, seek immediate medical attention.

Provide Artificial Respiration:
If breathing has stopped, provide artificial respiration.


Skin Contact:

Remove Contaminated Clothing:
Quickly and gently remove contaminated clothing.

Wash Skin:
Wash the affected area with plenty of water for at least 15 minutes, using a mild soap if available.

Seek Medical Attention:
If irritation, redness, or signs of chemical burns occur, seek medical attention.


Eye Contact:

Flush Eyes:
Immediately flush the eyes with gently flowing water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.

Seek Medical Attention:
If irritation, redness, or visual disturbances persist, seek immediate medical attention.


Ingestion:

Do Not Induce Vomiting:
Do not induce vomiting unless directed to do so by medical personnel.

Rinse Mouth:
Rinse the mouth with water.

Seek Medical Attention:
Seek immediate medical attention.
Provide the SDS or product label to healthcare professionals.


General First Aid Measures:

Personal Protection:
Wear appropriate personal protective equipment (PPE) when administering first aid.

Medical Attention:
If there is any doubt about the severity of exposure or symptoms, seek medical attention promptly.

Transport to Medical Facility:
If necessary, transport the affected person to a medical facility for further evaluation and treatment.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including chemical-resistant gloves, safety goggles or a face shield, protective clothing, and, if necessary, respiratory protection.
Consider the use of impervious aprons or clothing to prevent skin contact.

Ventilation:
Work in a well-ventilated area or use local exhaust ventilation to control airborne concentrations.
Ensure that mechanical ventilation systems are properly maintained and functioning.

Avoidance of Contact:
Minimize skin contact by wearing appropriate clothing and PPE.
Avoid inhalation of vapors or mists.
Use respiratory protection if necessary.

Preventive Measures:
Implement good industrial hygiene practices, including regular hand washing and avoiding touching the face, mouth, or eyes.
Establish and follow proper procedures for handling, transfer, and disposal.

Handling Equipment:
Use equipment made of materials compatible with purified isophthalic acid.
Ensure that containers and transfer equipment are properly labeled and free from contaminants.

Spill and Leak Response:
Have spill response measures in place, including absorbent materials, spill kits, and appropriate personal protective equipment.
Immediately contain and clean up spills to prevent environmental contamination.

Avoid Mixing Incompatibles:
Avoid mixing PIA with incompatible substances.
Refer to the SDS for information on incompatible materials.


Storage:

Storage Conditions:
Store purified isophthalic acid in a cool, dry, and well-ventilated area.
Keep away from sources of heat, sparks, open flames, and incompatible materials.

Temperature Control:
Store in a temperature-controlled environment, and avoid exposure to extreme temperatures.
Follow any specific temperature requirements provided by the manufacturer.

Container Compatibility:
Use containers made of materials compatible with PIA, such as high-density polyethylene (HDPE) or glass.
Ensure that containers are properly sealed and labeled with the necessary hazard information.

Segregation:
Segregate PIA from incompatible substances as per safety guidelines.
Clearly mark storage areas and containers to avoid confusion.

Avoid Direct Sunlight:
Keep containers shielded from direct sunlight to prevent degradation of the substance.

Fire Prevention:
Store away from oxidizing agents and combustible materials.
Implement fire prevention measures in the storage area, including the availability of fire extinguishing equipment.

Handling Precautions:
Store away from food and beverages.
Clearly mark storage areas with appropriate warning signs.

Regular Inspections:
Conduct regular inspections of storage areas for signs of damage, leaks, or deteriorating conditions.
Promptly address any issues identified during inspections.



SYNONYMS


1,3-Benzenedicarboxylic acid
o-Phthalic acid
Benzene-1,3-dicarboxylic acid
m-Phthalic acid
Isophthalic acid
Benzene-1,3-dicarboxylate
o-Carboxybenzene-1,3-dicarboxylic acid
3-Carboxybenzoic acid
meta-Phthalic acid
Benzene-1,3-dioic acid
m-Benzenedicarboxylic acid
Benzene-1,3-dicarboxylic acid
m-Benzene-1,3-dicarboxylic acid
m-Dicarboxybenzene
meta-Phthalic acid
3-Carboxybenzoic acid
1,3-Benzenedicarboxylic acid
o-Phthalic acid
Isophthalic acid
m-Benzenedicarboxylic acid
1,3-Dicarboxybenzene
Benzene-1,3-dioic acid
3-Carboxybenzene-1,3-dicarboxylic acid
Isophthalic acid, purified
Benzene-1,3-dicarboxylate
meta-Dicarboxybenzene
m-Phthalic acid
Benzene-1,3-dicarboxylic acid, purified
m-Carboxybenzene-1,3-dicarboxylic acid
Isophthalic acid, high purity
Benzene-1,3-dicarboxylic acid, pure
Isophthalic acid, technical grade
meta-Benzenedicarboxylic acid
1,3-Benzenedicarboxylate
Benzene-1,3-dicarboxylic acid, ultra-pure
High-purity isophthalic acid

4-Methylbenzenesulfonic acid monohydrate; Toluol-4-sulfonsäure; ácido tolueno-4-sulfónico; Acide toluène-4-sulfonique; p-tsa monohydrate; Methylbenzenesulfonic acid monohydrate; PTSA monohydrate; Toluenesulfonic acid monohydrate; Tosic acid monohydrate; cas no : 6192-52-5

PVA 1788 is a synthetic polymer derived from vinyl acetate through a polymerization process.
PVA 1788 refers to a specific grade of polyvinyl alcohol, and it is characterized by its molecular weight and other properties.
PVA 1788 is water-soluble and can be used in various applications due to its film-forming, adhesive, and emulsifying properties.



APPLICATIONS


PVA 1788 is widely used as a binder in the production of water-soluble packaging films, making it a sustainable choice for single-use applications.
Its film-forming properties find a crucial role in the manufacturing of adhesives, including paper adhesives and wood glues.

In the textile industry, PVA 1788 is employed as a sizing agent to improve fiber strength and facilitate smoother weaving processes.
Coatings with PVA 1788 contribute to enhancing the surface properties of paper, making it more suitable for printing and writing.
PVA 1788 serves as an emulsifying agent, stabilizing emulsions and suspensions in various industries such as cosmetics and food.

PVA 1788 is used in ceramics to enhance the green strength of clay bodies, ensuring better shape retention during forming.
PVA-based coatings and films, containing PVA 1788, are utilized in photography as binders for photographic emulsions, contributing to image stability.

PVA 1788's water-solubility makes it a valuable ingredient in water-based personal care products like shampoos and conditioners.
PVA 1788 's compatibility with various materials makes PVA 1788 a suitable candidate for creating composite materials with enhanced properties.

PVA 1788 acts as a release agent in mold-making and casting processes, preventing adhesion to molds and ensuring easy removal.
In the pharmaceutical industry, PVA 1788 is used as a binding agent in tablet formulations to hold the active ingredients together.
Its adhesion and film-forming properties are utilized in the production of adhesive labels, stickers, and tapes.

PVA-based coatings with PVA 1788 are applied to textiles to improve their strength, durability, and resistance to moisture.
The polymer, PVA 1788, is employed in the production of water-soluble pouches containing detergent or cleaning products for convenient and eco-friendly use.
Solutions containing PVA 1788 are used as coatings for paper and cardboard packaging materials, providing a protective layer and enhancing printability.

PVA 1788 acts as a binder in the production of ceramic components, ensuring structural integrity during firing.
In the construction industry, formulations containing PVA 1788 are used in paints and coatings, enhancing adhesion to various surfaces.

PVA 1788's water-soluble properties make it useful in the creation of temporary support structures, such as water-soluble scaffolds in tissue engineering.
The polymer, PVA 1788, finds application in the creation of artificial snow and snow effects in theatrical and film productions.
In the cosmetic industry, PVA 1788 is employed in the formulation of wound dressings and medical devices due to its biocompatibility and water-absorbing capabilities.
PVA 1788 contributes to the production of biodegradable packaging materials, reducing the environmental impact of disposable products.

PVA-based gels containing PVA 1788 are used in various industries, including cosmetics and food, for their gelling and stabilizing properties.
The polymer, PVA 1788, serves as a protective coating for fragile items during shipping and storage, preventing damage.

In food applications, PVA 1788 is used to encapsulate flavors, vitamins, and other active ingredients for controlled release.
The versatile applications of PVA 1788 span industries such as textiles, pharmaceuticals, packaging, cosmetics, and more, showcasing its adaptability and value in modern manufacturing and technology.
PVA 1788 is used in the production of water-soluble films for laundry detergent pods, offering convenient and mess-free usage.
Its adhesive properties make PVA 1788 suitable for manufacturing envelopes and stamps, ensuring secure sealing.
PVA-based coatings with PVA 1788 are applied to fabrics to create stiffened shapes for crafts and decorations.

In the beauty industry, PVA 1788 is used in the formulation of peelable face masks, aiding in deep cleansing and exfoliation.
In the agricultural sector, films containing PVA 1788 are employed as biodegradable mulching materials to enhance crop growth.

The polymer, PVA 1788, acts as a binder in the creation of ceramic glazes, contributing to the aesthetics and protection of pottery.
PVA 1788 solutions are utilized as a sizing agent in the production of fibers for woven and non-woven textiles.

In the manufacture of artificial flowers, adhesives containing PVA 1788 ensure the secure attachment of petals and components.
PVA 1788 films find applications in the textile and apparel industry for creating water-soluble embroidery backings.
PVA 1788 is used as a component in hydrogel dressings for wound care due to its absorbent and soothing properties.

Films containing PVA 1788 are utilized as temporary barriers in construction, protecting surfaces from overspray and damage.
In the food industry, PVA 1788 is employed to coat fruits and vegetables, extending their shelf life and maintaining freshness.
PVA 1788 acts as a binder in the creation of casting slips for ceramics, ensuring uniformity and ease of molding.
Solutions containing PVA 1788 are used to protect sensitive surfaces during paint spraying and finishing operations in the automotive industry.
The polymer, PVA 1788, serves as a dispersing agent in the production of paint and ink pigments, ensuring even color distribution.

In the creation of artificial snow for holiday decorations and winter scenes, PVA 1788's texture mimics real snow.
PVA 1788 is used in the formulation of polymer electrolyte membranes for fuel cells, aiding in energy conversion.
It is utilized in the creation of water-soluble packaging materials for agricultural chemicals and detergents.

PVA 1788 is employed as a lubricating and binding agent in the production of graphite-based lubricants.
The polymer, PVA 1788, is used in the textile industry to enhance fabric drape and hand, making it more comfortable to wear.
PVA-based adhesives containing PVA 1788 are used in the assembly of paperboard packaging, ensuring strong bonds and structural integrity.

In the creation of papier-mâché crafts, PVA 1788 is used as a binder to hold paper layers together.
PVA 1788 films are employed in the production of dissolvable laundry bags for hospitals and hotels, simplifying linen management.
PVA 1788 acts as a barrier coating in packaging materials to prevent oxygen and moisture from degrading contents.
The versatile applications of PVA 1788 extend across industries, including agriculture, construction, cosmetics, textiles, and more, making it an essential polymer with diverse and innovative uses.

PVA 1788 is used in the formulation of water-based inkjet printing inks, ensuring vibrant and durable color on various substrates.
PVA 1788 is employed in the creation of biodegradable seed tapes, facilitating precise and efficient planting in agriculture.
PVA-based hydrogels containing PVA 1788 are used in controlled drug delivery systems, gradually releasing medication for therapeutic purposes.
In the production of water-soluble films for dishwasher and laundry detergent pods, PVA 1788 ensures convenient and effective cleaning.
PVA 1788 is used to create flexible and transparent membranes in fuel cells, enhancing the efficiency of energy conversion.

Films containing PVA 1788 are utilized in the packaging of water-soluble fertilizers, providing easy and accurate dosing for agricultural applications.
The polymer, PVA 1788, is employed in the formulation of water-soluble binders for ceramics, facilitating precise shaping and firing.
PVA 1788 coatings are applied to concrete surfaces to provide a temporary moisture barrier during curing.
In the creation of biodegradable sutures, PVA 1788 contributes to wound closure and tissue healing in medical procedures.
The versatile applications of PVA 1788 reflect its adaptability and contribution to eco-friendly solutions across industries, making it a versatile and valuable polymer.

PVA 1788 is used in the formulation of water-based paints and coatings, contributing to improved adhesion and durability on various surfaces.
PVA 1788 finds application in the creation of water-soluble pouches containing cleaning agents, offering convenience and reducing waste.
PVA-based hydrogels containing PVA 1788 are utilized in wound dressings and medical bandages, providing a moist environment for healing.

In the automotive industry, solutions containing PVA 1788 are used as mold release agents, preventing adhesion in composite manufacturing.
PVA 1788 coatings are applied to fruits to create a protective layer, extending their shelf life and preserving quality during transportation.
The polymer, PVA 1788, is employed in the formulation of biodegradable detergent capsules, ensuring accurate dosing and reducing packaging waste.

PVA 1788's solubility in water is utilized in the creation of biodegradable seedling pots, promoting sustainable gardening practices.
In the creation of artificial tears and lubricating eye drops, PVA 1788 provides comfort and relief to individuals with dry eyes.

PVA 1788 is used in the formulation of water-soluble barrier coatings for concrete surfaces, protecting them during curing.
PVA 1788 finds application in the assembly of paper-based packaging materials, ensuring secure and reliable closures.
PVA-based adhesives containing PVA 1788 are employed in the construction of paperboard boxes and cartons, enhancing packaging integrity.
Films containing PVA 1788 are used in the production of biodegradable tea bags, offering an eco-friendly alternative to conventional tea packaging.

In the electronics industry, solutions containing PVA 1788 are used as temporary encapsulants in soldering processes, protecting components.
PVA 1788's water-soluble packaging films are used in the creation of single-use medical devices and diagnostic tests.
The polymer, PVA 1788, is employed in the formulation of water-based screen printing inks, suitable for various textiles and substrates.
PVA 1788 is used in the creation of biodegradable fishing lines and nets, reducing plastic waste in aquatic environments.
In the food industry, PVA 1788 coatings are applied to candies and confections, enhancing appearance and shelf life.

PVA-based gels containing PVA 1788 are utilized in horticulture as plant growth regulators, promoting healthy root development.
PVA 1788 is employed in the formulation of biodegradable dishwashing detergent capsules, minimizing environmental impact.
The polymer, PVA 1788, serves as a binder in the production of water-soluble ceramic molds for precision casting applications.
Films containing PVA 1788 are used in the production of dissolvable packaging materials for detergents and cleaning products.
PVA 1788 finds application in the creation of biodegradable agricultural mulch films, improving soil conditions and crop yield.

PVA 1788 coatings are used to create temporary barriers in construction, protecting surfaces from debris and damage.
In the creation of biodegradable single-use cutlery and utensils, PVA 1788 contributes to sustainable alternatives.
The numerous applications of PVA 1788 highlight its adaptability and contribution to eco-friendly solutions across industries, making it a versatile and valuable polymer.



DESCRIPTION


PVA 1788 is a synthetic polymer derived from vinyl acetate through a polymerization process.
PVA 1788 refers to a specific grade of polyvinyl alcohol, and it is characterized by its molecular weight and other properties.
PVA 1788 is water-soluble and can be used in various applications due to its film-forming, adhesive, and emulsifying properties.

PVA 1788 is a synthetic polymer derived from vinyl acetate through polymerization.
PVA 1788 is renowned for its water-solubility, forming viscous solutions when dissolved in water.
PVA 1788 exhibits film-forming properties, making it valuable in various applications.

PVA 1788 is available in different grades, with PVA 1788 referring to a specific molecular weight.
PVA 1788 finds extensive use in adhesives, including wood glues and paper adhesives.
As a textile sizing agent, it enhances the weaving process and boosts fiber strength.

In paper coatings, PVA 1788 improves surface characteristics and enhances printability.
Its emulsifying properties make it an effective component in emulsions and suspensions.
PVA 1788 is employed in water-soluble packaging films for single-use applications.

The film-forming nature of PVA finds a niche in personal care products like shampoos.
PVA solutions act as release agents in mold-making and casting processes.
Pharmaceutical industries use PVA as a binding agent in tablet formulations.
PVA 1788 plays a vital role in ceramics by enhancing green strength prior to firing.

In photography, PVA solutions serve as coatings and binders for photographic emulsions.
PVA 1788 is known for its versatility across industries due to its unique properties.
Its solubility in water allows for easy application and removal in various processes.

PVA 1788 contributes to improved adhesion and cohesion in adhesive formulations.
Its effectiveness as a textile sizing agent enhances the efficiency of weaving operations.
PVA 1788 's emulsifying properties aid in stabilizing suspensions and ensuring even dispersion.
In pharmaceuticals, PVA's binding properties help maintain the integrity of tablet formulations.
Its role in ceramics helps create strong and durable structures during firing.

PVA 1788 's water-soluble packaging films find applications in eco-friendly and convenient packaging solutions.
As a film-forming agent in personal care products, it adds a protective layer to hair strands.
PVA 1788 's compatibility with various materials makes it an essential ingredient in a wide range of products.
The unique combination of properties in PVA 1788 makes it a versatile polymer with applications spanning multiple industries.



PROPERTIES

Physical Properties:

State: Typically exists as a white to cream-colored powder, granules, or flakes.
Solubility: Water-soluble, forming viscous solutions when dissolved in water.
Odor: Generally odorless.
Density: The density can vary based on the grade and molecular weight of PVA.

Chemical Properties:

Chemical Formula: (C2H4O)n (represents the repeating unit of PVA polymer).
Hydrophilicity: Highly hydrophilic due to the presence of hydroxyl groups.
Chemical Reactivity: PVA is relatively inert and does not react with most common chemicals under normal conditions.
Degradability: PVA is biodegradable under certain conditions, especially in aerobic environments.

Mechanical Properties:

Flexibility: PVA films and coatings can be flexible and conform to various surfaces.
Strength: The mechanical strength of PVA can vary based on the grade and molecular weight.

Thermal Properties:

Melting Point: PVA does not have a distinct melting point, but it decomposes upon heating.
Thermal Stability: PVA starts to degrade at elevated temperatures, with decomposition starting around 200°C (392°F).



FIRST AID


Inhalation:

If inhaled and respiratory irritation occurs, move the affected person to fresh air.
If breathing difficulties persist, seek medical attention.


Skin Contact:

In case of skin contact, remove contaminated clothing and wash the affected skin with plenty of water and mild soap.
If irritation or redness occurs, seek medical advice.
Avoid using solvents or harsh chemicals to remove PVA from the skin.


Eye Contact:

Immediately flush the eyes with plenty of water for at least 15 minutes, holding the eyelids open.
Seek medical attention if irritation, redness, or discomfort persists.
Remove contact lenses if easily removable after flushing.


Ingestion:

If accidentally ingested, do not induce vomiting unless directed to do so by medical professionals.
Rinse the mouth and drink plenty of water to dilute the substance.
Seek immediate medical attention and provide medical personnel with relevant information about the ingested substance.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including chemical-resistant gloves, safety goggles, and protective clothing, when handling PVA to minimize skin and eye contact.

Ventilation:
Use PVA 1788 in a well-ventilated area to prevent the buildup of dust or vapors.
Consider using local exhaust ventilation to capture and remove any airborne particles.

Avoid Ingestion:
Never eat, drink, or smoke while handling PVA to prevent accidental ingestion.

Prevent Inhalation:
Avoid breathing in dust or vapors by using a dust mask or respirator if necessary, especially when working with powdered forms of PVA.

Spill Management:
In case of spills, contain and clean up PVA using appropriate methods, such as sweeping up dry material or wiping up with absorbent material.
Dispose of waste according to local regulations.

Avoid High Temperatures:
Store PVA 1788 away from heat sources, open flames, and direct sunlight, as exposure to high temperatures can lead to degradation or melting.

Prevent Static Buildup:
PVA 1788 can generate static electricity, so use appropriate precautions to prevent static discharge when handling the material.
Storage:

Storage Area:
Store PVA in a cool, dry, well-ventilated area away from incompatible materials, strong oxidizing agents, and sources of ignition.

Temperature:
Keep PVA 1788 at room temperature or below to maintain its stability and prevent thermal degradation.

Container:
Store PVA 1788 in tightly sealed containers to prevent moisture absorption, which can affect its water-solubility and properties.

Separation:
Store PVA 1788 away from chemicals that may react with it, as well as substances that could contaminate it.

Original Packaging:
Whenever possible, store PVA 1788 in its original packaging, which is often designed to protect it from environmental factors.

Avoid Humidity:
PVA 1788 is hygroscopic and can absorb moisture from the air. Store in a dry environment or use desiccants to maintain product integrity.

Handling of Bags/Containers:
When handling bags or containers of PVA, ensure proper lifting techniques to avoid strain or injury.



SYNONYMS


PVOH (Abbreviation for PolyVinyl Alcohol)
PVAL (Abbreviation for PolyVinyl Alcohol)
PVA Resin
PVO
Vinol
Alcotex
Polyethenol
Alcoholysis Resin
Vinylon
Vinol Fiber
Polyviol
Gohsenol
Kollicoat
Elvanol
Alcotex
Airvol
Kuralon
Alcotex
Mowiol
Gelvatol
Lurex
Kuraray
Gelvatol
Mowiol
Vinacol
Polyvinyl Hydrate
Ethanol Homopolymer
Poval
Vinylon
Povinal
Poval Resin
Ethylene Polymer
Ethenol Polymer
Alkoxol
Poval Polymer
Ethenol Homopolymer
Ethylene Alcohol Polymer
PVA Polymer
Ethenol Resin
Polyvinyl Polyol
Vinyl Alcohol Polymer
PVAL Resin
Ethenol Polymer
Alkoxol Resin
Vinol Resin
Ethenol Polymeric Compound
Vinyl Alcohol Homopolymer
Ethanol Vinyl Polymer
PVAL Polymer
Ethenol Polymer Compound
Alcotex
Hydroxyethylene Polymer
Alcoholysis Resin
Hydroxyethene Polymer
Poly(1-hydroxyethylene)
Hydroxyethyl Polymer
Polyvinyl Ether
Vinovyl Polymer
Alkoxol Polymer
Ethylene Alcohol Homopolymer
Hydroxyethylene Homopolymer
Poly(vinyl alcohol)
Hydroxyethene Homopolymer
Polyvinyl Alcohol Resin
Ethylene Polymer Alcohol
Vinylon Fiber
PVA Copolymer
Hydroxyethyl Resin
Vinyl Alcohol Homopolymer
Ethylene Vinyl Alcohol Polymer
Hydroxyethene Polymer Compound
Ethanol Vinyl Polymer
Ethenol Homopolymer Compound
PVA Compound
Hydroxyethylene Polymer Resin

PVM/MA COPOLYMER, N° CAS : 9011-16-9, Nom INCI : PVM/MA COPOLYMER. Classification : Polymère de synthèse. Ses fonctions (INCI): Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Agent fixant : Permet la cohésion de différents ingrédients cosmétiques. Stabilisateur d'émulsion : Favorise le processus d'émulsification et améliore la stabilité et la durée de conservation de l'émulsion. Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles. Agent de fixation capillaire : Permet de contrôler le style du cheveu. Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques. Noms français : 2,5-FURANDIONE, POLYMER WITH METHOXYETHENE; POLYMERE DU METHOXYETHENE ET DU FURANNE-2,5-DIONE. Noms anglais : MALEIC ANHYDRIDE, POLYMER WITH METHYL VINYL ETHER; METHYL VINYL ETHER-MALEIC ANHYDRIDE POLYMER ; Utilisation et sources d'émission. Fabrication de produits textiles, fabrication de colles ou adhésifs

cas no 9003-39-8 Plasdone; PVP; Polyvidone; Povidone; 1-vinylpyrrolidin-2-one homopolymer; Plasdone K29-32; Polyvinylpyrrolidone K30; Crospovidone;

PVP K 30 PVP K 30 is a film former in hair styling products. PVP is an emulsion stabilizer in creams and lotions. PVP can also be a dispersant for hair colorants. PVP K 30 is available as 100% powder and as 20% aqueous solution. PVP (Polyvinylpyrrolidone) K-30 polymer is a hygroscopic, amorphous polymer. PVP K 30 is a linear nonionic polymer that is soluble in water and organic solvents and is pH stable. PVP K 30 forms hard glossy transparent films and have adhesive and cohesive properties. General description Polyvinylpyrrolidone (PVP), also commercially known as K30, is a water soluble polymer. It has a hygroscopic nature with good adhesive properties. It has a stable pH and has the ability to form transparent films. Application PVP has a wide range of usage such as: • an adhesive for making gluesticks and metal adhesives • a dispersant for ceramics • coatings and inks • formation of synthetic fibres and textiles • porous membranes The PVP K 30 E- and I-series To fit more application areas, the E- and I-series of PVP K 30 copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. Storage and handling of PVP K 30 PVP K 30 copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 30 polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 30) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. USES PVP K 30 is used in as an adhesive in glue stick and hot-melt adhesives PVP K 30 is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP K 30 is used in as an emulsifier and disintegrant for solution polymerization PVP K 30 is used in increase resolution in photoresists for cathode ray tubes (CRT) PVP K 30 is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters PVP K 30 is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating PVP K 30 is used in as a thickening agent in tooth whitening gels PVP K 30 is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation PVP K 30 is used in as an additive to Doro's RNA extraction buffer PVP K 30 is used in as a liquid-phase dispersion enhancing agent in DOSY NMR PVP K 30 is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly PVP K 30 is used in as a stabilizing agent in all inorganic solar cells Other uses of PVP K-30 solution PVP K 30 binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. Applications and Usage Notes of PVP K 30 Adhesives – pressure-sensitive and water-remoistenable types, food packaging (indirect food contact), metal adhesives, abrasives, sandcore binder, rubber to metal adhesives and glue sticks. Ceramics – binder in high temperature fire-prepared products such as clay, pottery, porcelain, brick product, dispersant for ceramic media slurries and viscosity modifier. Coatings/lnks – digital printing coating, ball-point inks, protective colloid and leveling agent for emulsion polymers/ coatings/ printing inks, pigment dispersant, water colors for commercial art, temporary protective coatings, paper coatings, waxes and polishes. Electronic Applications – storage batteries, printed circuits, cathode ray tubes, binder for metal salts or amalgams in batteries, gold, nickel, copper and zinc plating, a thickener for solar gel ponds and as an adhesive to prevent leakage of batteries, serves as an expander in cadmium-type electrodes, binder in sintered-nickel powder plates. Membranes – macroporous, multiporous, desalination, gas separating, liquid ultrafiltration, hemodialysis, selective permeability types of membranes, hollow fiber membranes. Metallurgy – processing for both ferrous and non-ferrous metals, coating ingredient to aid or remove material from metal surfaces such as copper, nickel, zinc and aluminum, used in metal quenchant baths. Paper – cellulose papers, rag stock, rag stripping, copying paper, printing paper and electric insulating papers, paper adhesives. Polymerizations – acrylic monomers, unsaturated polyesters, olefins, including PVC, polystyrene beads, substrate for graft polymerization, template in acrylic polymerization. The PVP K 30 W copolymers PVP K 30 is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 30 W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 30 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 30, PVP K 30 E-535 and PVP K 30 E-335. In general, PVP K 30 is less hygroscopic than PVP. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. PVP K-30 20% Solution is a film former in hair styling products. It has an average molecular weight of 1,300,000 in Daltons. Polyvinylpyrrolidone. PVP K-30 solution is a film former. It is suggested for use in hair styling formualations. PVP K-30 solution is a 20 percent solution. It stabilizes emulsions, dispersions and suspensions. It forms clear, hard & glossy film. PVP K 30 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 30 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. What is PVP K 30 Copolymer? PVP K 30 Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. The advantages of using PVP K 30 copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP K 30 copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties • E = ethanol (EtOH), I = isopropanol, W = water, S = solid To fit many application areas, the E and I series of PVP K 30 copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. PVP K 30 copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 30 polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 30) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP K 30 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 30 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. PVP K 30 is a 70/30 copolymer of PVP K 30 and vinyl acetate supplied as a 50% solution in water. PVP K 30 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 30 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Key Attributes of PVP K 30 Polyvinylpyrrolidone (PVP) can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the pyrrolidone ring. High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts. Dispersancy, where components in a mixture are uniformly distributed through the use of polyvinylpyrrolidone. Hydrophilicity, where the water solubility of PVP is its dominant feature and frequently a factor along with other properties valuable in numerous applications. Adhesion, taking advantage of the higher molecular weight PVP formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application. Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques. In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP K 30) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP K 30 , N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP K 30 acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP K 30 finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP K 30 thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP K 30 used in industrial, specialty and imaging coatings, printing inks and paints. PVP K 30 provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. Uses of PVP K-30 solution Medical uses of PVP K-30 solution PVP K 30 was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP K 30 is used as a binder in many pharmaceutical tablets; it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption. The long-term effects of crospovidone or povidone within the lung are unknown.) PVP K 30 added to iodine forms a complex called povidone-iodine that possesses disinfectant properties. This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP K 30 is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost. PVP K 30 is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. PVP K 30 is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions. PVP K 30 is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP K 30 is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP K 30 can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP K 30 is useful for making an aqueous mounting medium. PVP K 30 can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production. Safety of PVP K 30 The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses, and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP K 30 has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP K 30 component of the solution. A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP. In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP. Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP K 30 instead. Properties of PVP K 30 PVP K 30 is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol, as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin). When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. A 2014 study found fluorescent properties of PVP K 30 and its oxidized hydrolyzate. History of PVP K 30 PVP K 30 was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP K 30 was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production. The PVP K 30 copolymer PVP K 30 copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. PVP K 30 copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 30 W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP K 30 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 30 E-735 copolymer, PVP K 30 E-535 copolymer and PVP K 30 E- 335 copolymer. In general, PVP K 30 copolymer is less hygroscopic than PVP. PVP K 30 copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP K 30 copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP K 30 copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP K 30 copolymer is used as a binder to allow the aqueous processing of photoresists. PVP K 30 is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene. PVP K 30 is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP K 30 monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives. Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone. PVP K 30 Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP K 30 (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP K 30 tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP K 30 Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid.

PVP K 60 Applications and Usage Notes Adhesives – pressure-sensitive and water-remoistenable types, food packaging (indirect food contact), metal adhesives, abrasives, sandcore binder, rubber to metal adhesives and glue sticks. Ceramics – binder in high temperature fire-prepared products such as clay, pottery, porcelain, brick product, dispersant for ceramic media slurries and viscosity modifier. Coatings/lnks – digital printing coating, ball-point inks, water colors for commercial art, temporary protective coatings, paper coatings. Lithography and Photography – foil emulsions, etch coatings, plate storage, gumming of lithographic plates, dampener roll solutions, photo and laser imaging processes. Metallurgy – processing for both ferrous and non-ferrous metals, coating ingredient to aid or remove material from metal surfaces such as copper, nickel, zinc and aluminum, used in metal quenchant baths. Paper – inorganic papers, cellulose papers, rag stock, rag stripping, coloring and beating operations, copying paper, printing paper and electric insulating papers, paper adhesives. PVP K 60 polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 60) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. Application of PVP K 60 Polyvinylpyrrolidone solution (PVP) is also known as K60 and can be used in a variety of applications such as biomedical, tissue engineering, and medical materials. To fit more application areas, the E- and I-series of PVP K 60 copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. PVP K 60 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 60 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. PVP K 60 Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. PVP K 60 is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 60 W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Other uses of PVP K-60 solution PVP K 60 binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP K 60 is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions. PVP K 60 is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP K 60 is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP K 60 can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP K 60 is useful for making an aqueous mounting medium. PVP K 60 can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production. Safety of PVP K 60 The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses, and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP K 60 has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP K 60 component of the solution. A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP. In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP. Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP K 60 instead. Plasticizers and polymers: Most PVP K 60 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 60, PVP K 60 E-535 and PVP K 60 E-335. In general, PVP K 60 is less hygroscopic than PVP. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Storage and handling of PVP K 60 PVP K 60 copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. PVP K-60 20% Solution is a film former in hair styling products. It has an average molecular weight of 1,300,000 in Daltons. Polyvinylpyrrolidone. PVP K-60 solution is a film former. It is suggested for use in hair styling formualations. PVP K-60 solution is a 20 percent solution. It stabilizes emulsions, dispersions and suspensions. It forms clear, hard & glossy film. In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP K 60) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP K 60 , N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. The advantages of using PVP K 60 copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP K 60 copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties Key Attributes of PVP K 60 -Polyvinylpyrrolidone (PVP) can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the pyrrolidone ring. -High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts. -Dispersancy, where components in a mixture are uniformly distributed through the use of polyvinylpyrrolidone. -Hydrophilicity, where the water solubility of PVP is its dominant feature and frequently a factor along with other properties valuable in numerous applications. -Adhesion, taking advantage of the higher molecular weight PVP formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application. -Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques. Applications and Usage Notes of PVP K 60 -Adhesives – pressure-sensitive and water-remoistenable types, food packaging (indirect food contact), metal adhesives, abrasives, sandcore binder, rubber to metal adhesives and glue sticks. -Ceramics – binder in high temperature fire-prepared products such as clay, pottery, porcelain, brick product, dispersant for ceramic media slurries and viscosity modifier. -Coatings/lnks – digital printing coating, ball-point inks, protective colloid and leveling agent for emulsion polymers/ coatings/ printing inks, pigment dispersant, water colors for commercial art, temporary protective coatings, paper coatings, waxes and polishes. -Electronic Applications – storage batteries, printed circuits, cathode ray tubes, binder for metal salts or amalgams in batteries, gold, nickel, copper and zinc plating, a thickener for solar gel ponds and as an adhesive to prevent leakage of batteries, serves as an expander in cadmium-type electrodes, binder in sintered-nickel powder plates. -Membranes – macroporous, multiporous, desalination, gas separating, liquid ultrafiltration, hemodialysis, selective permeability types of membranes, hollow fiber membranes. -Metallurgy – processing for both ferrous and non-ferrous metals, coating ingredient to aid or remove material from metal surfaces such as copper, nickel, zinc and aluminum, used in metal quenchant baths. -Paper – cellulose papers, rag stock, rag stripping, copying paper, printing paper and electric insulating papers, paper adhesives. -Polymerizations – acrylic monomers, unsaturated polyesters, olefins, including PVC, polystyrene beads, substrate for graft polymerization, template in acrylic polymerization. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. PVP K 60 copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP K 60 acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP K 60 finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP K 60 thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP K 60 used in industrial, specialty and imaging coatings, printing inks and paints. PVP K 60 provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. PVP K 60 is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene. PVP K 60 is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP K 60 monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives. Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone. PVP K 60 Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP K 60 (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP K 60 tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP K 60 Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. PVP K 60 polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 60) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP K 60 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 60 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. PVP K 60 is a 70/30 copolymer of PVP K 60 and vinyl acetate supplied as a 50% solution in water. PVP K 60 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 60 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Uses of PVP K-60 solution Medical uses of PVP K-60 solution PVP K 60 was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP K 60 is used as a binder in many pharmaceutical tablets; it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption. The long-term effects of crospovidone or povidone within the lung are unknown.) PVP K 60 added to iodine forms a complex called povidone-iodine that possesses disinfectant properties. This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP K 60 is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost. PVP K 60 is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Properties of PVP K 60 PVP K 60 is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol, as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin). When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP K 60 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 60 E-735 copolymer, PVP K 60 E-535 copolymer and PVP K 60 E- 335 copolymer. In general, PVP K 60 copolymer is less hygroscopic than PVP. USES of PVP K 60 It is used in as an adhesive in glue stick and hot-melt adhesives It is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP K 60 is used in as an emulsifier and disintegrant for solution polymerization It is used in increase resolution in photoresists for cathode ray tubes (CRT) PVP K 60 is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters It is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating It is used in as a thickening agent in tooth whitening gels PVP K 60 is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation It is used in as an additive to Doro's RNA extraction buffer It is used in as a liquid-phase dispersion enhancing agent in DOSY NMR PVP K 60 is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly PVP K 60 is used in as a stabilizing agent in all inorganic solar cells PVP K 60 copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP K 60 copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP K 60 copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP K 60 copolymer is used as a binder to allow the aqueous processing of photoresists. History of PVP K 60 PVP K 60 was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP K 60 was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production. The PVP K 60 copolymer PVP K 60 copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. PVP K 60 copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 60 W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution.

PVP K 85 PVP K 85 Solution is a hygroscopic, amorphous polymer supplied as a clear aqueous solution. It can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. This product is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. PVP products are recommended for dishwashing, fabric care, household cleaning, and industrial and institutional cleaning applications. Polyvinylpyrrolidone (PVP K 85). It is in form of aqueous solution. It is linear, random and is produced by the free-radical polymerization. It is hygroscopic and amorphous. It has high polarity, dispersany, adhesion and cohesion. It forms hard, glossy and oxygen permeable film. It is soluble in water and polar solvents. Insoluble in esters, ethers, ketones and hydrocarbons. Suitable for digital ink-jet printing. PVP K 85 100% Powder is soluble in water and many organic solvents and it forms hard, transparent, glossy film. PVP is compatible with most inorganic salts and many resins. PVP stabilizes emulsions, dispersions and suspensions. While PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K 85 100% Powder appears as a white powder. PVP (Polyvinylpyrrolidone) K-85 polymer is a hygroscopic, amorphous polymer. They are linear nonionic polymers that are soluble in water and organic solvents and are pH stable. PVP K 85 forms hard glossy transparent films and have adhesive, cohesive and dispersive properties. Key Attributes of PVP K 85  Polyvinylpyrrolidone (PVP) can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the pyrrolidone ring.  High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.  Dispersancy, where components in a mixture are uniformly distributed through the use of polyvinylpyrrolidone.  Hydrophilicity, where the water solubility of PVP is its dominant feature and frequently a factor along with other properties valuable to numerous applications.  Adhesion, taking advantage of the molecular weight PVP formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.  Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques. Applications and Usage Notes  Adhesives – pressure-sensitive and water-remoistenable types of adhesives, food packaging (indirect food contact), metal adhesives, abrasives, sandcore binder, rubber to metal adhesives and glue sticks.  Ceramics – binder in high temperature fire prepared products such as clay, pottery, porcelain, brick product, dispersant for ceramic media slurries and viscosity modifier.  Glass and Glass Fibers – acts as a binder, lubricant and coating agent.  Coatings/lnks – digital printing coating, ball-point inks, protective colloid and leveling agent for emulsion polymers/ coatings/ printing inks, pigment dispersant, water-colors for commercial art, temporary protective coatings, paper coatings, waxes and polishes.  Electronic Applications – storage batteries, printed circuits, cathode ray tubes, binder for metal salts or amalgams in batteries, gold, nickel, copper and zinc plating, a thickener for solar gel ponds and as an adhesive to prevent leakage of batteries, serves as an expander in cadmium-type electrodes, binder in sintered-nickel powder plates.  Lithography and Photography – foil emulsions, etch coatings, plate storage, gumming of litho- graphic plates, dampener roll solutions, photo and laser imaging processes, microencapsulation, thermal recording, carrier, finisher preserver of lithographic plates, thermal transfer recording ribbons and optical recording discs.  Fibers and Textiles – synthetic fibers, dyeing and printing, fugitive tinting, dye stripping and dispersant, scouring, delustering, sizing and finishing, greaseproofing aid, soil release agent. Widely used as dye dispersant and to disperse titanium dioxide.  Membranes – macroporous, multiporous, desalination, gas separating, liquid ultrafiltration, hemodialysis, selective permeability types of membranes, hollow fiber membranes.  Metallurgy – processing for both ferrous and non ferrous metals, coating ingredient to aid or remove material from metal surfaces such as copper, nickel, zinc and aluminum.  Paper – inorganic papers, cellulose papers, rag stock, rag stripping, coloring and beating operations, copying paper, printing paper and electric insulating papers, paper adhesives.  Polymerizations – acrylic monomers, unsaturated polyesters, olefins, including PVC, styrene beads, substrate for graft polymerization, template in acrylic polymerization.  Water and Waste Treatment, and Hygiene – clogging of reverse osmosis membranes, water treatment in fish hatchery ponds, removal of oil, dyes from waste water and waste water clarifier in papermaking, in deodorants for neutralization of irritant and poisonous gas, in air conditioning filters. Polyvinylpyrrolidone (PVP K 85) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/85 to 85/70 vinyl acetate to vinylpyrrolidone. PVP K 85 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (85, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 85 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. What is PVP K 85 Copolymer? PVP K 85 Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. Ashland offers formulators a series of vinylpyrrolidone/vinyl acetate copolymers. Members of the PVP K 85 copolymer series serve as primary film formers in a variety of products demanding different degrees of water resistance. These copolymers feature specific affinity for hair, skin and smooth surfaces such as wood, glass, paper, and metal, yet do not require solvents for removal. The advantages of using PVP K 85 copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP K 85 copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties • E = ethanol (EtOH), I = isopropanol, W = water, S = solid The PVP K 85 E and I copolymer Series To fit many application areas, the E and I series of PVP K 85 copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. The PVP K 85 copolymer PVP K 85 copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. The PVP K 85 W copolymers PVP K 85 copolymer is a 70/85 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 85 W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP K 85 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 85 E-735 copolymer, PVP K 85 E-535 copolymer and PVP K 85 E- 335 copolymer. In general, PVP K 85 copolymer is less hygroscopic than PVP. PVP K 85 copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP K 85 copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP K 85 copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP K 85 copolymer is used as a binder to allow the aqueous processing of photoresists. Storage and handling PVP K 85 copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 85 polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 85 ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/85 to 85/70 vinyl acetate to vinylpyrrolidone. PVP K 85 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (85, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 85 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP K 85 E- and I-series To fit more application areas, the E- and I-series of PVP K 85 copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP K 85 W copolymers PVP K 85 is a 70/85 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 85 W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 85 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 85, PVP K 85 E-535 and PVP K 85 E-335. In general, PVP K 85 is less hygroscopic than PVP. Abstract In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP K 85 ) copolymer compositions (70/85, 60/40, 50/50 and 85/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP K 85 , N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP K 85 acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP K 85 finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP K 85 thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP K 85 used in industrial, specialty and imaging coatings, printing inks and paints. PVP K 85 provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. PVP K 85 is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene.[2] PVP K 85 is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP K 85 monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives.[2] Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone. PVP K 85 Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP K 85 (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP K 85 tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. (See image below) Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP K 85 Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. The PVP K 85 E and I copolymer Series To fit many application areas, the E and I series of PVP K 85 copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-735, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. Storage and handling PVP K 85 copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 85 polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 85 ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/85 to 85/70 vinyl acetate to vinylpyrrolidone. PVP K 85 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (85, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 85 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP K 85 W copolymers PVP K 85 is a 70/85 copolymer of PVP K 85 and vinyl acetate supplied as a 50% solution in water. PVP K 85 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 85 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. USES Medical PVP K 85 was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP K 85 is used as a binder in many pharmaceutical tablets;[2] it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.[3] The long-term effects of crospovidone or povidone within the lung are unknown.) PVP K 85 added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.[4] This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP K 85 is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.[5] PVP K 85 is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Technical PVP K 85 is used in as an adhesive in glue stick and hot-melt adhesives PVP K 85 is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP K 85 is used in as an emulsifier and disintegrant for solution polymerization PVP K 85 is used in increase resolution in photoresists for cathode ray tubes (CRT)[9] PVP K 85 is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters PVP K 85 is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating PVP K 85 is used in as a thickening agent in tooth whitening gels[10] PVP K 85 is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation PVP K 85 is used in as an additive to Doro's RNA extraction buffer[citation needed] PVP K 85 is used in as a liquid-phase dispersion enhancing agent in DOSY NMR [11] PVP K 85 is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly[12] PVP K 85 is used in as a stabilizing agent in all inorganic solar cells[13] Other uses PVP K 85 binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP K 85 is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions.[14][15] PVP K 85 is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP K 85 is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP K 85 can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP K 85 is useful for making an aqueous mounting medium.[16] PVP K 85 can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production.[17] Safety of PVP K 85 The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses,[18] and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP K 85 has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP K 85 component of the solution.[19] A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP.[20] In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP.[21] Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP K 85 instead. Properties of PVP K 85 PVP K 85 is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol,[24] as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin).[25] When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. A 2014 study found fluorescent properties of PVP K 85 and its oxidized hydrolyzate. History of PVP K 85 PVP K 85 was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP K 85 was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production.

PVP K 90 PVP K 90 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 90 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. What is PVP K 90 Copolymer? PVP K 90 Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Storage and handling of PVP K 90 PVP K 90 copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 90 polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 90) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. The PVP K 90 E- and I-series To fit more application areas, the E- and I-series of PVP K 90 copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP K 90 W copolymers PVP K 90 is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 90 W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 90 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 90, PVP K 90 E-535 and PVP K 90 E-335. In general, PVP K 90 is less hygroscopic than PVP. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. PVP K-90 20% Solution is a film former in hair styling products. It has an average molecular weight of 1,300,000 in Daltons. Polyvinylpyrrolidone. PVP K-90 solution is a film former. It is suggested for use in hair styling formualations. PVP K-90 solution is a 20 percent solution. It stabilizes emulsions, dispersions and suspensions. It forms clear, hard & glossy film. Key Attributes of PVP K 90 Polyvinylpyrrolidone (PVP) can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the pyrrolidone ring. High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts. Dispersancy, where components in a mixture are uniformly distributed through the use of polyvinylpyrrolidone. Hydrophilicity, where the water solubility of PVP is its dominant feature and frequently a factor along with other properties valuable in numerous applications. Adhesion, taking advantage of the higher molecular weight PVP formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application. Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques. Applications and Usage Notes of PVP K 90 Adhesives – pressure-sensitive and water-remoistenable types, food packaging (indirect food contact), metal adhesives, abrasives, sandcore binder, rubber to metal adhesives and glue sticks. Ceramics – binder in high temperature fire-prepared products such as clay, pottery, porcelain, brick product, dispersant for ceramic media slurries and viscosity modifier. Coatings/lnks – digital printing coating, ball-point inks, protective colloid and leveling agent for emulsion polymers/ coatings/ printing inks, pigment dispersant, water colors for commercial art, temporary protective coatings, paper coatings, waxes and polishes. Electronic Applications – storage batteries, printed circuits, cathode ray tubes, binder for metal salts or amalgams in batteries, gold, nickel, copper and zinc plating, a thickener for solar gel ponds and as an adhesive to prevent leakage of batteries, serves as an expander in cadmium-type electrodes, binder in sintered-nickel powder plates. Membranes – macroporous, multiporous, desalination, gas separating, liquid ultrafiltration, hemodialysis, selective permeability types of membranes, hollow fiber membranes. Metallurgy – processing for both ferrous and non-ferrous metals, coating ingredient to aid or remove material from metal surfaces such as copper, nickel, zinc and aluminum, used in metal quenchant baths. Paper – cellulose papers, rag stock, rag stripping, copying paper, printing paper and electric insulating papers, paper adhesives. Polymerizations – acrylic monomers, unsaturated polyesters, olefins, including PVC, polystyrene beads, substrate for graft polymerization, template in acrylic polymerization. Abstract of PVP K-90 solution In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP K 90) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP K 90 , N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. The advantages of using PVP K 90 copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP K 90 copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties • E = ethanol (EtOH), I = isopropanol, W = water, S = solid The PVP K 90 E and I copolymer Series To fit many application areas, the E and I series of PVP K 90 copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. PVP K 90 copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 90 polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 90) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP K 90 copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 90 copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. PVP K 90 is a 70/30 copolymer of PVP K 90 and vinyl acetate supplied as a 50% solution in water. PVP K 90 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 90 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP K 90 acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP K 90 finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP K 90 thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP K 90 used in industrial, specialty and imaging coatings, printing inks and paints. PVP K 90 provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. PVP K 90 is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene. PVP K 90 is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP K 90 monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives. Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone. PVP K 90 Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP K 90 (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP K 90 tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP K 90 Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. Uses of PVP K-90 solution Medical uses of PVP K-90 solution PVP K 90 was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP K 90 is used as a binder in many pharmaceutical tablets; it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption. The long-term effects of crospovidone or povidone within the lung are unknown.) PVP K 90 added to iodine forms a complex called povidone-iodine that possesses disinfectant properties. This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP K 90 is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost. PVP K 90 is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Properties of PVP K 90 PVP K 90 is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol, as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin). When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. A 2014 study found fluorescent properties of PVP K 90 and its oxidized hydrolyzate. History of PVP K 90 PVP K 90 was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP K 90 was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production. The PVP K 90 copolymer PVP K 90 copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. PVP K 90 copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 90 W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP K 90 copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 90 E-735 copolymer, PVP K 90 E-535 copolymer and PVP K 90 E- 335 copolymer. In general, PVP K 90 copolymer is less hygroscopic than PVP. PVP K 90 copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP K 90 copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP K 90 copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP K 90 copolymer is used as a binder to allow the aqueous processing of photoresists. USES PVP K 90 is used in as an adhesive in glue stick and hot-melt adhesives PVP K 90 is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP K 90 is used in as an emulsifier and disintegrant for solution polymerization PVP K 90 is used in increase resolution in photoresists for cathode ray tubes (CRT) PVP K 90 is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters PVP K 90 is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating PVP K 90 is used in as a thickening agent in tooth whitening gels PVP K 90 is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation PVP K 90 is used in as an additive to Doro's RNA extraction buffer PVP K 90 is used in as a liquid-phase dispersion enhancing agent in DOSY NMR PVP K 90 is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly PVP K 90 is used in as a stabilizing agent in all inorganic solar cells Other uses of PVP K-90 solution PVP K 90 binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP K 90 is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions. PVP K 90 is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP K 90 is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP K 90 can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP K 90 is useful for making an aqueous mounting medium. PVP K 90 can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production. Safety of PVP K 90 The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses, and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP K 90 has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP K 90 component of the solution. A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP. In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP. Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP K 90 instead.

PVP K 90 is soluble in water and many organic solvents and it forms hard, transparent, glossy film.
PVP K 90 is compatible with most inorganic salts and many resins.
PVP K 90 stabilizes emulsions, dispersions and suspensions.

CAS: 9003-39-8
MF: CH4
MW: 16.04246
EINECS: 1312995-182-4

PVP K 90, also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone.
PVP K 90 is available in a range of molecular weights and related viscosities, and can be selected according to the desired application properties.
While PVP K 90 is used as a film former in hair styling products, PVP K 90 can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP K 90 can be used in toothpastes and mouthwashes.
PVP K 90 appears as a white powder.

PVP K 90 is abbreviated as PVP, and is the polymer of vinylpyrrolidone.
According to the different degree of polymerization, PVP K 90 is further classified into soluble PVP and insoluble PVPP (polyvinyl polypyrrolidone).
Molecular weight of the soluble PVP K 90 is 8,000 to 10,000.
The soluble PVP K 90 can be used as a precipitating agent which can be settle down through its action with polyphenols.
Using this method, PVP K 90 is easily to have residual PVP in the alcohol.
Due to the savings effect of PVP K 90 inside the human body, the World Health Organization doesn’t recommend to apply this substance.

In recent years, the use of soluble PVP K 90 has been rare.
Insoluble PVP K 90 system had began to be used in the beer industry since the early 1960s.
PVP K 90 has a relative molecule weight greater than the relative mass greater than 700,000.
PVP K 90 is a insoluble polymer derived from the further cross-linking and polymerization of PVP and can be used as an adsorbent of polyphenols with a good efficacy.

PVP K 90 is one of the three major pharmaceutical new excipients and can be used as the co-solvent of tablets, granules, and injection, as the glidant of capsules, as the dispersant agent of liquid preparations and the colorant, as the stabilizer of enzyme and heat sensitive drug, as the co-precipitating agent of poorly soluble drugs, and as the detoxicant of ophthalmic drugs and lubricants.
PVP K 90 is industrially used as expanded polystyrene additive, as the gelling agents for suspension polymerization, stabilizer, and fiber treating agents, paper processing aids, adhesives, and thickening agents.

PVP K 90 and its copolymers CAP is an important raw material of cosmetics, mainly used for hair retaining agent.
The film PVP K 90 formed in the hair is elastic and shiny, and has excellent carding property as well as being free of dust.
Adopting different category of resin can meet various kinds of relative humidity climatic conditions.
Therefore, PVP K 90 is an indispensable raw material in styling hair cream, hair gel, and mousse.
PVP K 90 can also be used for the cosmetics of skin moisturizing agents and the dispersants for grease based hair dying, also as foam stabilizers, and can improve the consistency of the shampoo.
Insoluble PVP K 90 is the stabilizer of beer and juice which can improve its transparency, color, and flavor.

PVP K 90 is a water soluble polyamide.
Commercially available PVP K 90 is divided into four viscosity grades according to its press K value (Fikentscher K value): K-15, K-30, K-60, K-90, with the average molecular weight being 10,000, 40000,160000, and 360000, respectively.
K value or molecular weight is an important factor which decides the various properties of PVP.
PVP K 90 is dissolved in water, chlorinated solvents, alcohol, amine, nitro-paraffin and low molecular weight fatty acids, and is mutually soluble with most inorganic salts and a variety of resin; insoluble in acetone and ether.

PVP K 90 used for the matrix of dropping pill matrix is odorless, tasteless, white to pale yellow waxy solid with the relative density being 1.062, and its 5% aqueous solution pH being 3 to 7.
PVP K 90 is hygroscopic and of good thermal stability, and can be dissolved in various kinds of organic solvents, and has high melting point.
Adding certain natural or synthetic polymers or organic compounds can effectively adjust the PVP K 90’s hygroscopicity and softness.
PVP K 90 is not prone to have chemical reaction.
Under normal storage conditions, dry PVP K 90 is quite stable.
PVP K 90 has excellent physical inertia and biocompatibility and has not stimulation to skin, eyes no stimulation with no allergic reactions and being non-toxic.

Because of the hydrogen bonding or complexation effect, PVP K 90’s viscosity is increased and this further inhibits the formation and growth of crystallized nuclei of drugs, making the drug being in the amorphous state.
The dropping pill whose matrix is PVP K 90 can enhance the dissolution and bioavailability of poorly soluble drugs.
In general, the greater the PVP K 90 amount, the higher dissolution and solubility of drug in the medium.
Susana et al have studied the dissolution of the PVP K 90 solid dispersant of the slightly soluble drug albendazole.
The increased amount of PVP K 90 can increase the dissolution rate and efficiency of drug inside the solid dispersant.

Teresa et al have studied the dissolution of the poorly soluble drugs, flunarizine in PVP K 90 solid dispersant and obtained similar conclusion.
PVP K 90 also found that the higher the content, the more significant increase in dissolution.
IR has showed that flunarizine and PVP K 90 has no chemical reaction except in some cases that a best dissolution efficacy is obtained only in certain ratio between some drugs with the PVP.
Tantishaiyakul et al has found that: when the ratio of piroxicam: PVP K 90 is 1:5 and 1:6, the dissolution of the solid dispersant is the largest with a 40 times as high as that of single drug within 5min.
PVP K 90 can also be dissolved in another molten dropping pill matrix, such as polyethylene glycol (PEG), polyoxyethylene monostearate (S-40), poloxamer and stearyl acid, glyceryl monostearate, etc for making complex matrix.

PVP K 90, a polymer of vinylpyrrolidinone, is an excipient used as a suspending and dispersing agent.
Injectable preparations containing polymers with a molecular weight in the order of 12,000 have caused painful local granulomatous lesions.
This has led to the withdrawal of PVP K 90 from such preparations in some countries.
PVP K 90 was formerly also used as a plasma expander but, because it was sequestered within the liver and spleen, this use has been discontinued.
However, PVP K 90 remains widely used as a vehicle for ophthalmic preparations, and as the major component of artificial tears.

PVP K 90 Chemical Properties
Melting point: >300 °C
Boiling point: 90-93 °C
Density: 1,69 g/cm3
Storage temp.: 2-8°C
Solubility H2O: soluble100mg/mL
Form: powder
Color: White to yellow-white
PH: 3.0-5.0
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
Merck: 14,7697
Stability: Stable. Incompatible with strong oxidizing agents.
Light sensitive. Hygroscopic.
InChI: InChI=1S/C8H15NO/c1-3-7(2)9-6-4-5-8(9)10/h7H,3-6H2,1-2H3
InChIKey: FAAHNQAYWKTLFD-UHFFFAOYSA-N
IARC: 3 (Vol. 19, Sup 7, 71) 1987
EPA Substance Registry System: PVP K 90 (9003-39-8)

Commonly used PVP K 90 level in the cosmetic industry is K-30.
Commercialized PVP K 90 is white and free flowing powder or solids with its content in the mass fraction of 20%, 30%, 45% and 50% aqueous solution.
PVP K 90 is soluble in water and is hygroscopic with a moisture equilibrium being 1/3 of the relative humidity of the environment.
Similar as the protein hydration action, each monomer associates with 0.5mol water.
PVP K 90 is not easy to have chemical reaction.

When stored at normal conditions, dry PVP K 90 is quite stable.
Solution undergone mildew treatment is also stable.
When heated in air to 150 °C or mixed with ammonium persulfate to heat at 90 °C for 30min, PVP K 90 will be exchanged to become a water-insoluble compound.
In the presence of azo compound or a dichromate oxidizing agent, light will cause PVP K 90 solution to become gel.
The co-heating of PVP K 90 solution with strong base (such as sodium silicate or trisodium phosphate) will generate precipitation.
Many different compounds can generate complexes with PVP.

For example, the complexes of PVP and iodine is very stable and have a good bactericidal effect and can reduce its toxicity; Adding the copolymers of the polyacrylic acid, tannic acid or methyl vinyl ether and maleic acid to the aqueous solution of PVP K 90 will generate insoluble complexes which are insoluble in water, alcohols and ketones.
But when being treated with base for neutralize the poly-acid can reverse the reaction; complexation between PVP K 90 and toxins, drugs and toxic chemicals can reduce their toxicity; some kinds of dyes can also form a strong complex with PVP K 90, which is the basis for using PVP K 90 as a dye bleaching agent.

PVP K 90 is the cross-linked homopolymer of pure vinylpyrrolidone.
PVP K 90 is hygroscopic and free-flowing white or off-white powder.
PVP K 90 has a slight foul smell.
PVP K 90 is insoluble in common solvents such as water, ethanol and ether.
So PVP K 90's molecule weight range can’t be measured.
However, PVP K 90 has ability to form complex with various kinds of substances (such as “Hu” class substance which can lead to the discoloration of a variety of wines and beverages discoloration).

Also PVP K 90 is easily to be removed after filtration because of its insolubility.
PVP K 90 occurs as a fine, white to creamy-white colored, odorless or almost odorless, hygroscopic powder.
PVP K 90 with K-values equal to or lower than 30 are manufactured by spray-drying and occur as spheres.
PVP K 90 and higher K-value povidones are manufactured by drum drying and occur as plates.

PVP K 90 is soluble in water and other polar solvents.
For example, PVP K 90 is soluble in various alcohols, such as methanol and ethanol, as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin).
When dry PVP K 90 is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water.
In solution, PVP K 90 has excellent wetting properties and readily forms films.
This makes PVP K 90 good as a coating or an additive to coatings.
A 2014 study found fluorescent properties of PVP K 90 and its oxidized hydrolyzate.

Uses
In the early 1950s, older, with shellac and oil-based hairspray had been rapidly replaced by PVP K 90 sprays which are still widely used until now.
PVP K 90 can form wet, transparent film on the hair which is shiny and has good lubrication effect.
PVP K 90 has good compatibility with a variety of good propellant and also has corrosion resistance.
PVP K 90 is widely used in hair styling, as the film former in combing products, as the creatinine and stabilizer of skin care lotions and creams, as the base stock material for eye and facial cosmetics and lipstick base, and also as hair dye dispersants and shampoo foam stabilizer.

PVP K 90 has detoxification effect and can reduce the irritation effects of other preparation on the skin and eyes.
PVP K 90 is also used as toothpaste detergents, gelling agents and antidotes.
The main drawback of PVP K 90 is its sensitivity to moisture.
However, this issue can be tackled by using its vinyl acetate copolymer in order to mitigate the effects of moisture and humidity.
In addition, PVP K 90 also has wide application in the pharmaceutical, beverage and textile industries.

Clarifying agent; pigment stabilizer; colloidal stabilizer; PVP K 90 is mainly used for beer clarifying and quality stabilizing (reference amount 8~20g/100L, maintained for 24h and remove it by filtration), and can also be applied in combination with enzymes (protease) and protein adsorbents.
PVP K 90 is also used to clarify the wine and as a stabilizer to prevent discoloration (reference amount 24~72g/100L).
Clarifying agents; stabilizers; thickeners agent; tablet fillers; dispersants; PVP K 90 of molecular weight 360,000 are often used as the clarifying agent of beer, vinegar, and grape wine.
Used as the fixing liquid for gas chromatography.

PVP K 90 is used as a colloidal stabilizer and clarifying agent for beer clarification. Apply proper amount according the demands of production.
PVP K 90 can be used for pharmacy, aquaculture, and livestock disinfectant for the sterilization of the skin and mucous.
PVP K 90 molecule has an amide bond for absorbing the hydroxyl groups located in polyphenol molecule to form hydrogen bonds, and therefore, can be used as the stabilizer of beer, fruit wine/grape wine, and drinking wine to extend their shelf life and improve the transparency, color and taste.
The products have two specifications: disposable type and regeneration type.
Disposable products are suitable for application by SMEs; renewable products demand the purchase of special filtration equipment; but since PVP K 90 is recyclable, it is suitable for large breweries for recycle application.

In daily cosmetics, PVP K 90 and its copolymer has good dispersion property and filming property, and thus being able to be used as a setting lotion, hair spray and styling mousse, as opacifiers for hair care agents, as the stabilizer of shampoo foam, as wave styling agent and as the dispersants and affinity agents in hair dye.
Adding PVP K 90 to cream, sunscreen, and hair removal agent can enhance wetting and lubricating effect.
Taking advantage of the excellent properties of PVP K 90 such as surface activity, film-forming and non-irritating to the skin, no allergic reactions, etc., has broad prospects in its application in hair care and skin care products.

PVP K 90 is used as an adhesive in glue sticks; an emulsifier and a disintegrant for solution polymerization; an additive to Doro's RNA extraction buffer; as a liquid-phase dispersion enhancing agent in diffusion-ordered spectroscopy (DOSY) NMR and as a thickening agent in tooth whitening gels.
PVP K 90 finds use in personal care products like shampoos and toothpastes, in ink for inkjet printers as well as in contact lens solutions.
PVP K 90 is used as a food additive and in the wine industry as a fining agent for white wine.
PVP K 90 is used as a capping agent to synthesize silver nanowires through a polyol process.

Pharmaceutical Applications
Although PVP K 90 is used in a variety of pharmaceutical formulations, it is primarily used in solid-dosage forms.
In tableting, PVP K 90 solutions are used as binders in wet-granulation processes.
PVP K 90 is also added to powder blends in the dry form and granulated in situ by the addition of water, alcohol, or hydroalcoholic solutions.
PVP K 90 is used as a solubilizer in oral and parenteral formulations, and has been shown to enhance dissolution of poorly soluble drugs from solid-dosage forms.

PVP K 90 solutions may also be used as coating agents or as binders when coating active pharmaceutical ingredients on a support such as sugar beads.
PVP K 90 is additionally used as a suspending, stabilizing, or viscosity-increasing agent in a number of topical and oral suspensions and solutions.
The solubility of a number of poorly soluble active drugs may be increased by mixing with povidone.
Special grades of pyrogen-free PVP K 90 are available and have been used in parenteral formulations.

Medical
PVP K 90 is used as a binder in many pharmaceutical tablets; it simply passes through the body when taken orally.
PVP K 90 added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.
PVP K 90 is used in various products such as solutions, ointment, pessaries, liquid soaps, and surgical scrubs.
PVP K 90 is sold under the trade names Pyodine and Betadine, among others.
PVP K 90 is used in pleurodesis (fusion of the pleura because of incessant pleural effusions).
For this purpose, PVP K 90 is as effective and safe as talc, and may be preferred because of easy availability and low cost.

PVP K 90 is used in some contact lenses and their packaging solutions.
PVP K 90 reduces friction, thus acting as a lubricant, or wetting agent, built into the lens.
PVP K 90 is used as a lubricant in some eye drops, e.g. Bausch & Lomb's Soothe.
PVP K 90 was used as a plasma volume expander for trauma victims after the 1950s.

PVP K 90 is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping.
Autopsies have found that PVP K 90 contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.
The long-term effects of crospovidone or povidone within the lung are unknown.

Technical
PVP K 90 is also used in many technical applications:
as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process,
as an emulsifier and disintegrant for solution polymerization,
to increase resolution in photoresists for cathode ray tubes (CRT),
in aqueous metal quenching,
for production of membranes, such as dialysis and water purification filters,
as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating,
as a thickening agent in tooth whitening gels,
as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms,(syrups, soft gelatine capsules) and as an inhibitor of recrystallisation,
as an additive to Doro's RNA extraction buffer,
as a liquid-phase dispersion enhancing agent in DOSY NMR,
as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle, synthesis and their self-assembly,
as a stabilizing agent in all inorganic solar cells.

Other uses
PVP K 90 binds to polar molecules exceptionally well, owing to its polarity.
This has led to PVP K 90's application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers.
PVP K 90 is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes.
PVP K 90 has also been used in contact lens solutions and in steel-quenching solutions.
PVP K 90 is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some.
As a food additive, PVP K 90 is a stabilizer and has E number E1201.
PVPP (crospovidone) is E1202.

PVP K 90 is also used in the wine industry as a fining agent for white wine and some beers.
In in-vitro fertilisation laboratories, PVP K 90 is used to slow down spermatozoa in order to capture them for e.g. ICSI.
In molecular biology, PVP K 90 can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer.
PVP K 90 is also exceptionally good at absorbing polyphenols during DNA purification.
Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR.
In microscopy, PVP is useful for making an aqueous mounting medium.
PVP K 90 can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production.

Identification Test
Solubility: soluble in water, ethanol and chloroform and insoluble in ether.
This is measured by the OT-42 method.
Dichromate precipitation test: in 5 mL of2% sample solution, add 5 mL dilute hydrochloric acid solution (TS-117), further add 5 mL of water plus 2 mL of 10% potassium dichromate solution and 2ml.
This should form an orange precipitate.
Take 75 mg of cobalt nitrate and 300 mg of ammonium thiocyanate for being dissolved in 2ml of water; add 5 mL of 2% aqueous sample solution; after the mixing, add dilute hydrochloric acid test solution (TS-117) for acidification.
This should form light blue precipitate.
Take 5 mL of 2% sample solution; add 1 mL of 25% hydrochloric acid, 5 mL of 5% barium chloride and 1 mL 5% molybdenum tungsten phosphoric acid solution.

This should generate a lot of white precipitate which gradually turns blue in the sunlight.
The pH value of 5% sample solution should be 3.0 to 3.7.
This is measured by conventional means.
Adding a few drops of iodine test solution (TS-124) to 5 mL of 0.5% sample solution should produce a deep red color.
Take 1 g of sample, add water to 10 ml as a suspension, add 0.1 mL of iodine test solution (TS-124), after mixing by shaking for 30s, iodine test solution should fade (to distinguish polyvinylpyrrolidone due to that polyvinylpyrrolidone can form red color).
Add 1 mL of starch test solution (TS-235), after shaking and mixing, there should be no blue color formed. to produce blue.

Production method
PVP K 90's crude product comes from the polymerization of vinylpyrrolidone under basic catalyst or the existence of N, N'-divinyl amidine and further cross-inking reaction.
Then use water, 5% acetic acid and 50% ethanol for reflux to until extract ≤50mg/kg (for over 3h).
The 30% to 60% aqueous solution of the purified 1-vinyl-2-pyrrolidone, in the presence of ammonia or amines and also with hydrogen peroxide as the catalyst, has cross-linking and homo-polymerization reaction at a temperature of 50 °C and subject to further purification to obtain the final product.

PVP K 90 is manufactured by the Reppe process.
Acetylene and formaldehyde are reacted in the presence of a highly active copper acetylide catalyst to form butynediol, which is hydrogenated to butanediol and then cyclodehydrogenated to form butyrolactone.
PVP K 90 is produced by reacting butyrolactone with ammonia.
This is followed by a vinylation reaction in which pyrrolidone and acetylene are reacted under pressure.
The monomer, vinylpyrrolidone, is then polymerized in the presence of a combination of catalysts to produce povidone.

Contact Allergens
PVP K 90 is widely used as is in cosmetics such as hair care products and in medical products.
PVP K 90 acts as iodophor in iodine-polyvinylpyrrolidone.
PVP K 90 is an irritant and has been claimed as the allergen in some cases of dermatitis from iodine-polyvinylpyrrolidone (although iodine is more likely the hapten).
PVP K 90 may cause type I contact urticaria or anaphylaxis.

Biochem/physiol Actions
PVP K 90 can bind to polyphenol.
Thus, PVP K 90 is known to be used for RNA isolation from plants rich in polyphenols.
PVP K 90 is extensively used in the synthesis of nanoparticles.

Synonyms
N-VINYL-2-PYRROLIDONE
88-12-0
1-vinylpyrrolidin-2-one
N-Vinylpyrrolidone
1-Vinyl-2-pyrrolidone
9003-39-8
N-Vinyl-2-pyrrolidinone
1-Vinyl-2-pyrrolidinone
Vinylpyrrolidone
Povidone
1-ethenylpyrrolidin-2-one
N-Vinylpyrrolidinone
2-Pyrrolidinone, 1-ethenyl-
1-Vinylpyrrolidone
Vinylbutyrolactam
Vinylpyrrolidinone
V-Pyrol
Luviskol
Plasdone
1-Vinylpyrrolidinone
25249-54-1
Vinyl-2-pyrrolidone
N-Vinyl pyrrolidone
1-Ethenyl-2-pyrrolidinone
N-Vinylpyrrolidone-2
2-Pyrrolidinone, 1-vinyl-
1-Vinyl-2-pyrrolidinone, monomer
PVP
NSC 10222
MPK 90
PVP 40
DTXSID2021440
143 RP
AT 717
1-vinyl-pyrrolidin-2-one
K 15
K 90
PVP-40
CHEBI:82551
MFCD00003197
NSC-10222
76H9G81541
DTXCID101440
WLN: /T5NVTJ AY*1*/
MFCD01076626
CAS-88-12-0
K 25
K 115
HSDB 7231
EINECS 201-800-4
BRN 0110513
CCRIS 8581
PovidonePVP
vinyl pyrrolidone
UNII-76H9G81541
N-vinyl-pyrrolidone
N -vinylpyrrolidinone
1-vinyl-2-pyrrolidon
POVIDONE MONOMER
VINYLBUTYLOLACTAM
N-vinylpyrrolidin-2-one
N-vinyl pyrrolidin-2-one
N-vinyl-pyrrolidin-2-one
PVP K3O
Crospovidone ~40,000
EC 201-800-4
SCHEMBL10869
WLN: T5NVTJ A1U1
PVP K15
PVP K30
PVP-K30
POVIDONE MONOMER [MI]
VINYL PYRROLIDONE (VP)
CHEMBL1878943
PVP - K-30 (Pharm Grade)
N-VINYL PYRROLIDONE [INCI]
1-Vinyl-2-pyrrolidone(stabilized with 200ppm Ammonium hydroxide)
NSC10222
Tox21_202462
Tox21_300073
NSC114022
NSC142693
NSC683040
N-Vinyl-2-pyrrolidone, optical grade
Polyvinylpyrrolidone (MW ~40,000)
AKOS000119985
N-VINYL-2-PYRROLIDONE [IARC]
AT18510
CS-W020981
FG-0420
NSC-114022
NSC-142693
NSC-683040
NCGC00166252-01
NCGC00166252-02
NCGC00166252-03
NCGC00254200-01
NCGC00260011-01
2-PYRROLIDINONE, 1-ETHENYL- [HSDB]
FT-0608329
FT-0645144
FT-0655284
V0026
EN300-19745
C19548
A817742
A843417
Q420628
SR-01000944531
J-015891
SR-01000944531-1
W-100417
1-Vinyl-2-pyrrolidinone, SAJ first grade, >=99.0%
F8881-5579
Z104475034
3-CHLORO-5,6-DIFLUORO-1-BENZOTHIOPHENE-2-CARBONYLCHLORIDE
1-Vinyl-2-pyrrolidinone, contains sodium hydroxide as inhibitor, >=99%
1-Vinyl-2-pyrrolidinone, Pharmaceutical Secondary Standard; Certified Reference Material
1-Vinyl-2-pyrrolidone (stabilized with N,N'-Di-sec-butyl-p-phenylenediamine)

SYNONYMS PVP, Polyvidone, Povidone;Polyvinylpyrrolidone Standard (Mw 3500 K12);Polyvinylpyrrolidone Standard (Mw 8.000 K16-18);Polyvinylpyrrolidone Standard (Mw 10.000 K13-18);Polyvinylpyrrolidone Standard (Mw 24.000 K23-27);Polyvinylpyrrolidone Standard (Mw 30.000);Polyvinylpyrrolidone Standard (Mw 40.000 K-30);Polyvinylpyrrolidone Standard (Mw 55.000);Polyvinylpyrrolidone Standard (Mw 58.000 K29-32) CAS NO:9003-39-8

PVP K 90 Solution PVP K-90 20% Solution is a film former in hair styling products. It has an average molecular weight of 1,300,000 in Daltons. Polyvinylpyrrolidone. PVP K-90 solution is a film former. It is suggested for use in hair styling formualations. PVP K-90 solution is a 20 percent solution. It stabilizes emulsions, dispersions and suspensions. It forms clear, hard & glossy film. Key Attributes of PVP K 90 solution  Polyvinylpyrrolidone (PVP) can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the pyrrolidone ring.  High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.  Dispersancy, where components in a mixture are uniformly distributed through the use of polyvinylpyrrolidone.  Hydrophilicity, where the water solubility of PVP is its dominant feature and frequently a factor along with other properties valuable in numerous applications.  Adhesion, taking advantage of the higher molecular weight PVP formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.  Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques. Applications and Usage Notes of PVP K 90 solution  Adhesives – pressure-sensitive and water-remoistenable types, food packaging (indirect food contact), metal adhesives, abrasives, sandcore binder, rubber to metal adhesives and glue sticks.  Ceramics – binder in high temperature fire-prepared products such as clay, pottery, porcelain, brick product, dispersant for ceramic media slurries and viscosity modifier.  Coatings/lnks – digital printing coating, ball-point inks, protective colloid and leveling agent for emulsion polymers/ coatings/ printing inks, pigment dispersant, water colors for commercial art, temporary protective coatings, paper coatings, waxes and polishes.  Electronic Applications – storage batteries, printed circuits, cathode ray tubes, binder for metal salts or amalgams in batteries, gold, nickel, copper and zinc plating, a thickener for solar gel ponds and as an adhesive to prevent leakage of batteries, serves as an expander in cadmium-type electrodes, binder in sintered-nickel powder plates.  Membranes – macroporous, multiporous, desalination, gas separating, liquid ultrafiltration, hemodialysis, selective permeability types of membranes, hollow fiber membranes.  Metallurgy – processing for both ferrous and non-ferrous metals, coating ingredient to aid or remove material from metal surfaces such as copper, nickel, zinc and aluminum, used in metal quenchant baths.  Paper – cellulose papers, rag stock, rag stripping, copying paper, printing paper and electric insulating papers, paper adhesives.  Polymerizations – acrylic monomers, unsaturated polyesters, olefins, including PVC, polystyrene beads, substrate for graft polymerization, template in acrylic polymerization. What is PVP K 90 solution Copolymer? PVP K 90 solution Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Storage and handling of PVP K 90 solution PVP K 90 solution copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 90 solution polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 90 solution) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP K 90 solution copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 90 solution copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP K 90 solution E- and I-series To fit more application areas, the E- and I-series of PVP K 90 solution copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP K 90 solution W copolymers PVP K 90 solution is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 90 solution W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 90 solution copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 90 solution, PVP K 90 solution E-535 and PVP K 90 solution E-335. In general, PVP K 90 solution is less hygroscopic than PVP. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. Ashland offers formulators a series of vinylpyrrolidone/vinyl acetate copolymers. Members of the PVP K 90 solution copolymer series serve as primary film formers in a variety of products demanding different degrees of water resistance. These copolymers feature specific affinity for hair, skin and smooth surfaces such as wood, glass, paper, and metal, yet do not require solvents for removal. The advantages of using PVP K 90 solution copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP K 90 solution copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties • E = ethanol (EtOH), I = isopropanol, W = water, S = solid The PVP K 90 solution E and I copolymer Series To fit many application areas, the E and I series of PVP K 90 solution copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. Abstract of PVP K-90 solution In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP K 90 solution) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP K 90 solution , N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP K 90 solution acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP K 90 solution finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP K 90 solution thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP K 90 solution used in industrial, specialty and imaging coatings, printing inks and paints. PVP K 90 solution provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. PVP K 90 solution is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene. PVP K 90 solution is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP K 90 solution monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives. Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone. PVP K 90 solution Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP K 90 solution (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP K 90 solution tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. (See image below) Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP K 90 solution Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. PVP K 90 solution copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 90 solution polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 90 solution) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP K 90 solution copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 90 solution copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. PVP K 90 solution is a 70/30 copolymer of PVP K 90 solution and vinyl acetate supplied as a 50% solution in water. PVP K 90 solution is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 90 solution copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Uses of PVP K-90 solution Medical uses of PVP K-90 solution PVP K 90 solution was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP K 90 solution is used as a binder in many pharmaceutical tablets; it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption. The long-term effects of crospovidone or povidone within the lung are unknown.) PVP K 90 solution added to iodine forms a complex called povidone-iodine that possesses disinfectant properties. This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP K 90 solution is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost. PVP K 90 solution is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Technical uses of PVP K-90 solution PVP K 90 solution is used in as an adhesive in glue stick and hot-melt adhesives PVP K 90 solution is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP K 90 solution is used in as an emulsifier and disintegrant for solution polymerization PVP K 90 solution is used in increase resolution in photoresists for cathode ray tubes (CRT) PVP K 90 solution is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters PVP K 90 solution is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating PVP K 90 solution is used in as a thickening agent in tooth whitening gels PVP K 90 solution is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation PVP K 90 solution is used in as an additive to Doro's RNA extraction buffer PVP K 90 solution is used in as a liquid-phase dispersion enhancing agent in DOSY NMR PVP K 90 solution is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly PVP K 90 solution is used in as a stabilizing agent in all inorganic solar cells Other uses of PVP K-90 solution PVP K 90 solution binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP K 90 solution is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions. PVP K 90 solution is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP K 90 solution is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP K 90 solution can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP K 90 solution is useful for making an aqueous mounting medium. PVP K 90 solution can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production. Safety of PVP K 90 solution The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses, and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP K 90 solution has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP K 90 solution component of the solution. A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP. In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP. Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP K 90 solution instead. Properties of PVP K 90 solution PVP K 90 solution is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol, as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin). When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. A 2014 study found fluorescent properties of PVP K 90 solution and its oxidized hydrolyzate. History of PVP K 90 solution PVP K 90 solution was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP K 90 solution was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production. The PVP K 90 solution copolymer PVP K 90 solution copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. PVP K 90 solution copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 90 solution W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP K 90 solution copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 90 solution E-735 copolymer, PVP K 90 solution E-535 copolymer and PVP K 90 solution E- 335 copolymer. In general, PVP K 90 solution copolymer is less hygroscopic than PVP. PVP K 90 solution copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP K 90 solution copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP K 90 solution copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP K 90 solution copolymer is used as a binder to allow the aqueous processing of photoresists.

PVP K 90 Solution 20% PVP K 90 Solution 20% is a film former in hair styling products. PVP is an emulsion stabilizer in creams and lotions. PVP can also be a dispersant for hair colorants. PVP K 90 is available as 100% powder and as 20% aqueous solution. PVP (Polyvinylpyrrolidone) K-90 polymer is a hygroscopic, amorphous polymer. PVP K 90 solution 20% is a linear nonionic polymer that is soluble in water and organic solvents and is pH stable. PVP K 90 solution 20% forms hard glossy transparent films and have adhesive and cohesive properties. Ashland Specialty Ingredients has the capability to dial the K-value to meet specific customer needs. PVP K-90 20% Solution is a film former in hair styling products. It has an average molecular weight of 1,300,000 in Daltons. Polyvinylpyrrolidone. PVP K-90 solution by Ashland Specialty Chemical is a film former. It is suggested for use in hair styling formualations. PVP K-90 solution is a 20 percent solution. It stabilizes emulsions, dispersions and suspensions. It forms clear, hard & glossy film. Key Attributes of PVP K 90 solution 20%  Polyvinylpyrrolidone (PVP) can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the pyrrolidone ring.  High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.  Dispersancy, where components in a mixture are uniformly distributed through the use of polyvinylpyrrolidone.  Hydrophilicity, where the water solubility of PVP is its dominant feature and frequently a factor along with other properties valuable in numerous applications.  Adhesion, taking advantage of the higher molecular weight PVP formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.  Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques. Applications and Usage Notes of PVP K 90 solution 20%  Adhesives – pressure-sensitive and water-remoistenable types, food packaging (indirect food contact), metal adhesives, abrasives, sandcore binder, rubber to metal adhesives and glue sticks.  Ceramics – binder in high temperature fire-prepared products such as clay, pottery, porcelain, brick product, dispersant for ceramic media slurries and viscosity modifier.  Coatings/lnks – digital printing coating, ball-point inks, protective colloid and leveling agent for emulsion polymers/ coatings/ printing inks, pigment dispersant, water colors for commercial art, temporary protective coatings, paper coatings, waxes and polishes.  Electronic Applications – storage batteries, printed circuits, cathode ray tubes, binder for metal salts or amalgams in batteries, gold, nickel, copper and zinc plating, a thickener for solar gel ponds and as an adhesive to prevent leakage of batteries, serves as an expander in cadmium-type electrodes, binder in sintered-nickel powder plates.  Membranes – macroporous, multiporous, desalination, gas separating, liquid ultrafiltration, hemodialysis, selective permeability types of membranes, hollow fiber membranes.  Metallurgy – processing for both ferrous and non-ferrous metals, coating ingredient to aid or remove material from metal surfaces such as copper, nickel, zinc and aluminum, used in metal quenchant baths.  Paper – cellulose papers, rag stock, rag stripping, copying paper, printing paper and electric insulating papers, paper adhesives.  Polymerizations – acrylic monomers, unsaturated polyesters, olefins, including PVC, polystyrene beads, substrate for graft polymerization, template in acrylic polymerization. What is PVP K 90 solution 20% Copolymer? PVP K 90 solution 20% Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Storage and handling PVP K 90 solution 20% copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 90 solution 20% polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 90 solution 20% ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP K 90 solution 20% copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 90 solution 20% copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP K 90 solution 20% E- and I-series To fit more application areas, the E- and I-series of PVP K 90 solution 20% copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP K 90 solution 20% W copolymers PVP K 90 solution 20% is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 90 solution 20% W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 90 solution 20% copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 90 solution 20%, PVP K 90 solution 20% E-535 and PVP K 90 solution 20% E-335. In general, PVP K 90 solution 20% is less hygroscopic than PVP. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. Ashland offers formulators a series of vinylpyrrolidone/vinyl acetate copolymers. Members of the PVP K 90 solution 20% copolymer series serve as primary film formers in a variety of products demanding different degrees of water resistance. These copolymers feature specific affinity for hair, skin and smooth surfaces such as wood, glass, paper, and metal, yet do not require solvents for removal. The advantages of using PVP K 90 solution 20% copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP K 90 solution 20% copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties • E = ethanol (EtOH), I = isopropanol, W = water, S = solid The PVP K 90 solution 20% E and I copolymer Series To fit many application areas, the E and I series of PVP K 90 solution 20% copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. Abstract In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP K 90 solution 20% ) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP K 90 solution 20% , N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP K 90 solution 20% acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP K 90 solution 20% finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP K 90 solution 20% thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP K 90 solution 20% used in industrial, specialty and imaging coatings, printing inks and paints. PVP K 90 solution 20% provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. PVP K 90 solution 20% is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene.[2] PVP K 90 solution 20% is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP K 90 solution 20% monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives.[2] Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone. PVP K 90 solution 20% Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP K 90 solution 20% (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP K 90 solution 20% tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. (See image below) Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP K 90 solution 20% Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. The PVP K 90 solution 20% E and I copolymer Series To fit many application areas, the E and I series of PVP K 90 solution 20% copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-735, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. Storage and handling PVP K 90 solution 20% copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP K 90 solution 20% polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP K 90 solution 20% ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP K 90 solution 20% copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP K 90 solution 20% copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP K 90 solution 20% W copolymers PVP K 90 solution 20% is a 70/30 copolymer of PVP K 90 solution 20% and vinyl acetate supplied as a 50% solution in water. PVP K 90 solution 20% is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP K 90 solution 20% copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Uses Medical PVP K 90 solution 20% was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP K 90 solution 20% is used as a binder in many pharmaceutical tablets;[2] it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.[3] The long-term effects of crospovidone or povidone within the lung are unknown.) PVP K 90 solution 20% added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.[4] This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP K 90 solution 20% is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.[5] PVP K 90 solution 20% is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Technical PVP K 90 solution 20% is used in as an adhesive in glue stick and hot-melt adhesives PVP K 90 solution 20% is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP K 90 solution 20% is used in as an emulsifier and disintegrant for solution polymerization PVP K 90 solution 20% is used in increase resolution in photoresists for cathode ray tubes (CRT)[9] PVP K 90 solution 20% is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters PVP K 90 solution 20% is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating PVP K 90 solution 20% is used in as a thickening agent in tooth whitening gels[10] PVP K 90 solution 20% is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation PVP K 90 solution 20% is used in as an additive to Doro's RNA extraction buffer[citation needed] PVP K 90 solution 20% is used in as a liquid-phase dispersion enhancing agent in DOSY NMR [11] PVP K 90 solution 20% is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly[12] PVP K 90 solution 20% is used in as a stabilizing agent in all inorganic solar cells[13] Other uses PVP K 90 solution 20% binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP K 90 solution 20% is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions.[14][15] PVP K 90 solution 20% is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP K 90 solution 20% is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP K 90 solution 20% can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP K 90 solution 20% is useful for making an aqueous mounting medium.[16] PVP K 90 solution 20% can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production.[17] Safety of PVP K 90 solution 20% The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses,[18] and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP K 90 solution 20% has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP K 90 solution 20% component of the solution.[19] A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP.[20] In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP.[21] Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP K 90 solution 20% instead. Properties of PVP K 90 solution 20% PVP K 90 solution 20% is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol,[24] as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin).[25] When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. A 2014 study found fluorescent properties of PVP K 90 solution 20% and its oxidized hydrolyzate. History of PVP K 90 solution 20% PVP K 90 solution 20% was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP K 90 solution 20% was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production. The PVP K 90 solution 20% copolymer PVP K 90 solution 20% copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. The PVP K 90 solution 20% W copolymers PVP K 90 solution 20% copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP K 90 solution 20% W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP K 90 solution 20% copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP K 90 solution 20% E-735 copolymer, PVP K 90 solution 20% E-535 copolymer and PVP K 90 solution 20% E- 335 copolymer. In general, PVP K 90 solution 20% copolymer is less hygroscopic than PVP. PVP K 90 solution 20% copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP K 90 solution 20% copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP K 90 solution 20% copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP K 90 solution 20% copolymer is used as a binder to allow the aqueous processing of photoresists.

PVP K90 (Polyvinylpyrrolidone K90) solution 20% is a liquid formulation containing 20% Polyvinylpyrrolidone with a specific average molecular weight, commonly known as PVP K90.
PVP K 90 solution 20% is a water-soluble polymer derived from the polymerization of vinylpyrrolidone monomers.

CAS Number: 9003-39-8
EC Number: 284-724-8

Polyvinylpyrrolidone, PVP, Povidone, Polyvidone, PVP K90, PVP K30, PVP-I, N-Vinylpyrrolidone polymer, Povidone K90, Povidone K30, Povidone K15, Povidone K17, Povidone K25, Povidone K29/32, Povidone K60, Povidone K85, Polyvinylpyrrolidone K90, Polyvinylpyrrolidone K30, Polyvinylpyrrolidone K15, Polyvinylpyrrolidone K17, Polyvinylpyrrolidone K25, Polyvinylpyrrolidone K29/32, Polyvinylpyrrolidone K60, Polyvinylpyrrolidone K85, PVP iodine complex, PVP/VA copolymer, PVP/VA S-630, PVP/VA 64, PVP/VA W-735, PVP/VA E-335, PVP/VA 73W, PVP/VA 64P, PVP/VA S-630 (W), PVP/VA 73W (W), PVP/VA 735, PVP/VA W-735 (W), PVP/VA 64L, PVP/VA 735L, PVP/VA E-335 (W), PVP/VA S-333, PVP/VA E-335 (W) (W), PVP/VA 73L, PVP/VA W-930, PVP/VA 923, PVP/VA 64L (W), PVP/VA W-930 (W), PVP/VA 923L, PVP/VA 64P (W), PVP/VA E-335 (W) (W), PVP/VA S-630 (W) (W), PVP/VA 73W (W) (W), PVP/VA 64L (W) (W), PVP/VA W-735 (W) (W), PVP/VA 735L (W) (W), PVP/VA W-930 (W) (W), PVP/VA 923L (W) (W), PVP/VA S-630, PVP/VA E-335, PVP/VA W-930, PVP/VA 923.



APPLICATIONS


PVP K 90 solution 20% is widely used in the pharmaceutical industry as a binder in tablet formulations, enhancing the cohesion of the tablets.
PVP K 90 solution 20% serves as a disintegrant in pharmaceutical tablets, aiding in the quick disintegration of the tablet in the digestive system.
PVP K 90 solution 20% is utilized in the production of fast-dissolving oral films, providing a convenient and effective drug delivery method.

In oral care products, such as toothpaste and mouthwash, PVP contributes to stability, texture, and consistency.
The film-forming properties of PVP make it valuable in the cosmetic industry, especially in the formulation of hairsprays and styling gels.
PVP K 90 solution 20% is a common ingredient in topical formulations, where it stabilizes and enhances the consistency of ointments, creams, and gels.

PVP K 90 solution 20% is employed in transdermal drug delivery systems to improve the absorption of drugs through the skin.
PVP K 90 solution 20% is used as an antiseptic in healthcare and first aid products, such as wound care solutions.

The pharmaceutical industry utilizes different grades of PVP, such as PVP K30 and PVP K90, based on specific molecular weight requirements.
PVP K 90 solution 20% is a key component in the production of contact lens solutions, providing lubricating and cleaning properties.
PVP K 90 solution 20% is found in over-the-counter medications for its pharmaceutical and therapeutic properties.

PVP K 90 solution 20% contributes to the stability and shelf life of certain formulations due to its stabilizing effects.
In the food industry, PVP is used as a clarifying agent in the production of beverages.
PVP K 90 solution 20% is employed in the creation of specialty coatings for pharmaceutical tablets, ensuring uniformity and stability.
PVP K 90 solution 20% is used in the production of wound care products, such as dressings and adhesive tapes.

PVP K 90 solution 20% is included in the formulation of instant cold packs, contributing to the gel-like consistency when activated.
PVP K 90 solution 20% is a valuable component in the cosmetic industry, contributing to the formulation of mascara for its film-forming characteristics.
PVP K 90 solution 20% is utilized in the creation of adhesives, enhancing their viscosity and adhesive properties.

The construction industry uses PVP K 90 solution 20% in cement formulations to improve workability and reduce water demand.
PVP K 90 solution 20% is found in the textile industry as a dye dispersant and for its film-forming properties in sizing agents.
PVP K 90 solution 20% is included in the formulation of paints and coatings, contributing to film formation and dispersing properties.

PVP K 90 solution 20% is employed in the creation of hydrogels for medical applications, such as wound dressings and drug delivery systems.
PVP K 90 solution 20% is utilized in the paper industry to improve paper strength and reduce linting.
PVP K 90 solution 20% is part of the excipients used to improve the bioavailability of poorly water-soluble drugs.
In the agricultural sector, PVP is used in crop protection formulations, ensuring the uniform distribution of active ingredients.

PVP K 90 solution 20% is employed in the production of specialty inks for screen printing, ensuring durability and adhesion on various surfaces.
In the agricultural sector, PVP is included in seed coatings to improve germination rates and protect seeds from environmental stress.
The cosmetic industry uses PVP K 90 solution 20% in the creation of nail polishes for its film-forming and adhesive properties.

PVP K 90 solution 20% is found in the formulation of detergents and cleaning products, improving stability and viscosity.
PVP K 90 solution 20% is used in the creation of adhesives for postage stamps, ensuring secure bonding and adhesion to envelopes.

PVP K 90 solution 20% is included in the formulation of smoke-generating formulations for firefighting training exercises and signaling devices.
In the printing industry, PVP is utilized as a binder in ink formulations, improving adhesion to various surfaces.
PVP K 90 solution 20% is employed in the manufacturing of photographic emulsions as a protective colloid for the dispersion of light-sensitive silver halide crystals.

The semiconductor industry uses PVP in the production of photoresists, facilitating the patterning process in microfabrication.
PVP K 90 solution 20% is utilized in the formulation of lubricating eye drops, providing comfort and moisture to dry eyes.
In the production of ophthalmic solutions, PVP is used as a stabilizer to maintain the clarity and stability of the solution.

PVP K 90 solution 20% is found in the formulation of fuel additives, where it acts as a dispersant to prevent the formation of deposits in engines.
The textile industry uses PVP in sizing agents to improve fiber cohesion and reduce yarn breakage during weaving.
PVP K 90 solution 20% is employed in the creation of chromatography resins, aiding in the separation of biomolecules in bioprocessing.
In the manufacturing of ion exchange resins, PVP contributes to their stability and ion absorption capabilities.

PVP K 90 solution 20% is included in the formulation of wound sealants, providing a protective barrier and promoting tissue adhesion.
PVP K 90 solution 20% is utilized in the development of air fresheners and deodorizing products for its ability to encapsulate and release fragrances.
PVP K 90 solution 20% is found in the formulation of hydrogels for medical applications, such as wound dressings and drug delivery systems.

PVP K 90 solution 20% is employed in the creation of antistatic coatings for plastics and textiles, helping prevent the buildup of static electricity.
The paint and coatings industry uses PVP as a thickening agent, enhancing the viscosity and application properties of coatings.
PVP K 90 solution 20% is included in the formulation of imaging agents for medical diagnostic purposes, improving contrast in imaging techniques.

In the production of ceramics, PVP serves as a binder, contributing to the green strength of molded ceramic articles.
PVP K 90 solution 20% is utilized in the creation of anti-aging skincare products, contributing to the texture and effectiveness of the formulations.
The creation of anti-fog coatings for eyeglasses and camera lenses involves the use of PVP for its film-forming properties.
PVP K 90 solution 20% is continuously explored for emerging applications, showcasing its adaptability and versatility in various industries.

PVP K 90 solution 20% is employed in the production of photovoltaic devices to improve the stability and efficiency of perovskite solar cells.
The cosmetic industry utilizes PVP K 90 solution 20% in the creation of hair care products like shampoos and conditioners for its conditioning and film-forming properties.

In the formulation of battery electrolytes, PVP is used to contribute to the stability and performance of the electrolyte solution.
PVP K 90 solution 20% is included in the production of latex gloves, where it serves as a coating agent to facilitate easy donning and doffing.
PVP K 90 solution 20% is used in the formulation of antifreeze products, aiding in the prevention of scale and corrosion in cooling systems.

PVP K 90 solution 20% is found in the creation of film coatings for pharmaceutical tablets, providing a protective and aesthetically pleasing layer.
The semiconductor industry employs PVP K 90 solution 20% in the production of inkjet inks to enhance color stability and prevent clogging of printheads.
In the agricultural sector, PVP is included in crop protection formulations to ensure the uniform distribution of active ingredients.

PVP K 90 solution 20% is used in the manufacturing of imaging agents for medical diagnostic purposes, improving contrast in imaging techniques.
The construction industry utilizes PVP in the production of concrete admixtures to improve workability and reduce water demand.

PVP K 90 solution 20% is part of the formulation of antistatic coatings for plastics and textiles, preventing the buildup of static electricity.
The creation of hydrogels for medical applications, such as wound dressings and drug delivery systems, involves the use of PVP.
PVP K 90 solution 20% is utilized in the development of inkjet inks to enhance color stability and prevent nozzle clogging.

The production of firefighting foam involves the use of PVP as a stabilizing agent for the foam.
PVP K 90 solution 20% is included in the creation of adhesives for specialty applications, such as postage stamps and specialty packaging.
The textile industry uses PVP as a dye carrier, improving color uniformity in dyeing processes.

PVP K 90 solution 20% is employed in the formulation of detergents and cleaning products, improving stability and viscosity.
In the manufacturing of ion exchange resins, PVP contributes to their stability and ion absorption capabilities.

PVP K 90 solution 20% is used in the formulation of air fresheners and deodorizing products for its ability to encapsulate and release fragrances.
PVP K 90 solution 20% is found in the production of firefighting training exercises, where it contributes to the formulation of smoke-generating formulations.
In the creation of antifog coatings for eyeglasses and camera lenses, PVP is used for its film-forming properties.

The semiconductor industry employs PVP in the production of photoresists, facilitating the patterning process in microfabrication.
PVP K 90 solution 20% is included in the formulation of wound care products like adhesive tapes, providing secure and comfortable adhesion.
The cosmetic industry utilizes PVP K 90 solution 20% in the formulation of specialty inks for screen printing, ensuring durability and adhesion.
PVP K 90 solution 20% is continually explored for emerging applications, showcasing its adaptability and versatility in various industries.



DESCRIPTION


PVP K90 (Polyvinylpyrrolidone K90) solution 20% is a liquid formulation containing 20% Polyvinylpyrrolidone with a specific average molecular weight, commonly known as PVP K90.
PVP K 90 solution 20% is a water-soluble polymer derived from the polymerization of vinylpyrrolidone monomers.

In the context of PVP K90 solution 20%, the "20%" indicates the concentration of the PVP K90 polymer in the solution.
It means that 20% of the solution's total weight is composed of PVP K90, while the remaining 80% typically consists of water.
The specific properties and applications of the solution depend on the concentration and molecular weight of the PVP K90 used.

PVP K 90 solution 20% is a versatile polymer with various applications in industries such as pharmaceuticals, cosmetics, personal care, and others.
Its properties, including water solubility, film-forming capabilities, and biocompatibility, make it valuable in formulations for different purposes.
The 20% solution format allows for easy incorporation into formulations without the need for additional dissolution steps.

PVP K 90 solution 20% is a versatile water-soluble polymer widely used in various industries.
PVP K 90 solution 20% is known for its exceptional solubility in water, producing clear and colorless solutions.

PVP K 90 solution 20% is derived from the polymerization of vinylpyrrolidone monomers.
PVP K 90 solution 20% has film-forming properties, making it valuable in coatings and pharmaceutical applications.
The chemical structure of PVP consists of repeating units of 1-ethenyl-2-pyrrolidinone.
PVP K 90 solution 20% is biocompatible and widely employed in pharmaceuticals, cosmetics, and personal care products.

PVP K 90 solution 20% exhibits hygroscopic behavior, absorbing and retaining moisture from the environment.
PVP K 90 solution 20% is often used as a stabilizing agent, contributing to the shelf life of certain formulations.
In the pharmaceutical industry, different grades like PVP K30 and PVP K90 offer specific molecular weight ranges.

PVP K 90 solution 20% serves as a binder in tablet formulations, enhancing their cohesion and disintegration properties.
PVP K 90 solution 20% finds application in oral care products, contributing to stability and consistency in mouthwashes and toothpaste.
PVP K 90 solution 20%'s film-forming characteristics make it beneficial in cosmetic formulations, including hairsprays.

As a disintegrant in tablets, PVP aids in the quick disintegration of pharmaceuticals in the digestive system.
PVP K 90 solution 20% is used in the production of fast-dissolving oral films, improving drug delivery.
PVP K 90 solution 20% is employed as a stabilizing agent in ointments, creams, and gels in the pharmaceutical and cosmetic industries.
PVP K 90 solution 20% iodine complex serves as an antiseptic in various healthcare and first aid products.

PVP K 90 solution 20% is utilized in transdermal drug delivery systems for controlled release applications.
PVP K 90 solution 20% contributes to the clarity and stability of solutions in ophthalmic and contact lens products.

In the food industry, PVP clarifies beverages and aids in the removal of haze-forming substances.
PVP K 90 solution 20% is a common ingredient in the production of specialty coatings for pharmaceutical tablets.

Its hygroscopic nature makes PVP suitable for formulations requiring moisture retention.
The cosmetic industry utilizes PVP in various products, such as mascaras, for its film-forming properties.
PVP K 90 solution 20% is employed in the creation of adhesives, contributing to their viscosity and bonding strength.

PVP K 90 solution 20%'s water solubility allows for easy incorporation into a variety of aqueous formulations.
PVP K 90 solution 20% continues to be an essential component in a wide range of applications due to its diverse and beneficial properties.



PROPERTIES


Chemical Formula: (C6H9NO)n, where n represents the number of repeating units in the polymer chain.
Molecular Weight: Varies depending on the specific grade of PVP (e.g., PVP K30, PVP K90).
Chemical Structure: Consists of repeating units of 1-ethenyl-2-pyrrolidinone.
CAS Number: 9003-39-8.
Solubility: Highly soluble in water, forming clear and colorless solutions.
Appearance: Typically white or off-white powder or solid.
Odor: Generally odorless.
Melting Point: Decomposes before reaching a specific melting point.
Boiling Point: Decomposes under high temperatures.
Density: Varies depending on the molecular weight and specific form of Povidone.
pH: PVP solutions are typically neutral.
Hygroscopicity: Exhibits hygroscopic behavior, absorbing and retaining moisture from the environment.
Film-Forming: Possesses film-forming properties, contributing to its use in various coatings and applications.
Biocompatibility: Generally considered biocompatible and safe for use in pharmaceuticals and medical applications.
Stability: Stable under normal storage conditions but may be affected by extreme temperatures and humidity.
Viscosity: The viscosity of PVP solutions can be adjusted based on concentration.
Compatibility: Compatible with a wide range of other substances, including drugs, polymers, and cosmetic ingredients.
Refractive Index: Varies depending on the molecular weight and concentration of the PVP solution.
Flash Point: Not applicable as it is not a flammable substance.



FIRST AID


Inhalation:

If PVP dust or aerosol is inhaled and respiratory discomfort occurs, move the affected person to an area with fresh air.
If breathing difficulties persist, seek medical attention.
Provide respiratory support if necessary, such as administering oxygen by a trained professional.


Skin Contact:

In case of skin contact, promptly wash the affected area with soap and water.
Remove contaminated clothing and ensure thorough rinsing of the skin.
If irritation or allergic reactions occur, seek medical advice.
If there is a significant exposure, use appropriate protective clothing to prevent further contact.


Eye Contact:

If PVP comes into contact with the eyes, immediately flush the eyes with gently flowing water for at least 15 minutes, holding the eyelids open.
Seek medical attention if irritation persists or if there is any sign of injury.
Remove contact lenses, if applicable, after the initial eye rinse.


Ingestion:

If PVP is ingested accidentally, rinse the mouth with water.
Ingesting PVP is generally not harmful, but seek medical attention if there are concerns or if large amounts are ingested.
Do not induce vomiting unless instructed to do so by medical professionals.


General First Aid Measures:

If any adverse reactions, such as skin irritation or respiratory discomfort, occur after exposure to PVP, seek medical assistance promptly.
If seeking medical attention, provide healthcare professionals with details about the specific PVP product and the nature of exposure.
Be prepared to provide information on the concentration and form of PVP involved in the exposure.
If available, have the safety data sheet (SDS) or product information accessible for medical professionals.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including gloves and safety goggles, when handling PVP.
Use chemical-resistant gloves to minimize skin contact.
In case of prolonged or repeated exposure, consider wearing protective clothing.

Ventilation:
Work in a well-ventilated area or use local exhaust ventilation to control airborne concentrations.
If handling in an enclosed space, ensure proper ventilation systems are in place to minimize inhalation risks.

Avoidance of Contact:
Avoid direct skin and eye contact with PVP.
Take precautions to prevent inhalation of dust or aerosols.
Minimize exposure through the use of engineering controls and personal protective equipment.

Handling Procedures:
Follow good manufacturing and laboratory practices when working with PVP.
Use appropriate tools and equipment to minimize the generation of dust or aerosols during handling.

Spill Response:
In case of a spill, use suitable absorbent materials to contain and clean up the spilled substance.
Dispose of waste according to local regulations and in accordance with the product's safety data sheet (SDS).

Storage Compatibility:
Store PVP away from incompatible materials, such as strong acids, bases, and oxidizing agents.
Check compatibility with storage containers to prevent chemical reactions.

Labeling:
Ensure containers are properly labeled with the correct product information, hazard symbols, and safety precautions.
Maintain clear and visible labeling on secondary containers in case of transfer.


Storage:

Temperature:
Store PVP in a cool, dry place.
Avoid exposure to extreme temperatures, as excessive heat or cold may affect the stability of the substance.

Container Integrity:
Ensure that storage containers are tightly sealed to prevent contamination or evaporation.
Regularly inspect containers for any signs of damage or leaks.

Ventilation During Storage:
If stored in an enclosed area, provide adequate ventilation to prevent the accumulation of vapors.

Storage Conditions:
Store PVP in accordance with the manufacturer's recommendations.
Keep the substance away from direct sunlight and incompatible materials.

Separation from Food and Feed:
Store PVP away from food, beverages, and animal feed.
Use separate storage areas to avoid cross-contamination.

Handling Precautions:
Follow proper handling procedures when transferring PVP between containers or dispensing it for use.
Minimize the risk of spills during storage and handling.

Fire Prevention:
PVP is generally not flammable, but it's advisable to keep it away from open flames, sparks, or potential ignition sources.
Store in areas compliant with fire safety regulations.

Emergency Response:
Have appropriate emergency response equipment, such as spill containment materials and fire extinguishers, readily available.

CAS NUMBER: 9003-39-8 Linear Formula (C6H9NO)n MDL number MFCD00149016 3D model (JSmol) Interactive image Abbreviations PVP, PVPP, NVP, PNVP ChEMBL ChEMBL1909074 ☒ ChemSpider none ECHA InfoCard 100.111.937 E number E1201 (additional chemicals) SMILES Properties Chemical formula (C6H9NO)n Molar mass 2,500 - 2,500,000 g·mol-1 Appearance white to light yellow, hygroscopic, amorphous powder Density 1.2 g/cm3 Melting point 150 to 180 °C (302 to 356 °F; 423 to 453 K) (glass temperature) Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Appearance (Colour) White to off - white Appearance (Form) Crystalline powder Solubility (Turbidity) 10% aq. solution Clear Nitrogen content (N) 11.5 - 12.5% pH (5% aq. solution) 3.0 - 7.0 Sulphated Ash max. 0.1% Heavy Metals (Pb) max. 0.001% K-value ~ 30 Vinyl pyrrolidone max. 0.8% Water (KF) max. 5% PVP K-30 is a hygroscopic, amorphous polyvinylpyrrolidone. Used in industrial, specialty and imaging coatings & paints and as a media component in digital ink jet-printing. Offers high polarity, dispersancy, hydrophilicity, adhesion, cohesivity and high glass transition temperature. PVP K-30 can be plasticized with water and most common organic plasticizers. They are linear nonionic polymers thar are soluble in water and organi solvents and are pH stable. PVP K-30 forms hard glossy transparent films and have adhesive, cohesive and dispersive properties. PVP K-30 100% Powder is soluble in water and many organic solvents and it forms hard, transparent, glossy film. PVP is compatible with most inorganic salts and many resins. PVP stabilizes emulsions, dispersions and suspensions. While PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-30 100% Powder appears as a white powder. Applications adhesives, ceramics, glass (fibers), coating/inks, electronic appliations, lithography and photography, fibers and textiles, membranes, metallurgy, paper, polymerizations, water and waste teratment, and hygiene. Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone: PVP was used as a plasma volume expander for trauma victims after the 1950s. It is used as a binder in many pharmaceutical tablets;[2] it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.[3] The long-term effects of crospovidone or povidone within the lung are unknown.) PVP added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.[4] This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. It is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.[5] PVP is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Examples of this use include Bausch & Lomb's Ultra contact lenses with MoistureSeal Technology[6] and Air Optix contact lens packaging solution (as an ingredient called "copolymer 845").[7] PVP is used as a lubricant in some eye drops, Soothe.[8] Technical PVP is also used in many technical applications: as an adhesive in glue stick and hot-melt adhesivesas a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process as an emulsifier and disintegrant for solution polymerization to increase resolution in photoresists for cathode ray tubes (CRT)[9] in aqueous metal quenching for production of membranes, such as dialysis and water purification filters as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating as a thickening agent in tooth whitening gels[10] as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation as an additive to Doro's RNA extraction buffer[citation needed] as a liquid-phase dispersion enhancing agent in DOSY NMR [11] as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly[12] as a stabilizing agent in all inorganic solar cells[13] Other uses PVP binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions.[14][15] PVP is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP is useful for making an aqueous mounting medium.[16] PVP can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production.[17] Safety The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses,[18] and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP component of the solution.[19] A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP.[20] In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP.[21] Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP instead.[22][23] Properties PVP is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol,[24] as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin).[25] When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. A 2014 study found fluorescent properties of PVP and its oxidized hydrolyzate.[26] History PVP was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production Vinylpyrrolidone polymer Polyvinylpyrrolidone is abbreviated as PVP, and is the polymer of vinylpyrrolidone. According to the different degree of polymerization, it is further classified into soluble PVP and insoluble PVPP (polyvinyl polypyrrolidone). Molecular weight of the soluble PVP is 8,000 to 10,000.The soluble PVP can be used as a precipitating agent which can be settle down through its action with polyphenols. Using this method, it is easily to have residual PVP in the alcohol. Due to the savings effect of PVP inside the human body, the World Health Organization doesn't recommend to apply this substance. In recent years, the use of soluble PVP has been rare. Insoluble PVPP system had began to be used in the beer industry since the early 1960s. It has a relative molecule weight greater than the relative mass greater than 700,000. It is a insoluble polymer derived from the further cross-linking and polymerization of PVP and can be used as an adsorbent of polyphenols with a good efficacy. The molecular formula of Polyvinylpyrrolidone The molecular formula of Polyvinylpyrrolidone Polyvinylpyrrolidone PVP is one of the three major pharmaceutical new excipients and can be used as the co-solvent of tablets, granules, and injection, as the glidant of capsules, as the dispersant agent of liquid preparations and the colorant, as the stabilizer of enzyme and heat sensitive drug, as the co-precipitating agent of poorly soluble drugs, and as the detoxicant of ophthalmic drugs and lubricants. It is industrially used as expanded polystyrene additive, as the gelling agents for suspension polymerization, stabilizer, and fiber treating agents, paper processing aids, adhesives, and thickening agents. Polyvinylpyrrolidone PVP and its copolymers CAP is an important raw material of cosmetics, mainly used for hair retaining agent. The film it formed in the hair is elastic and shiny, and has excellent carding property as well as being free of dust. Adopting different category of resin can meet various kinds of relative humidity climatic conditions. Therefore, it is an indispensable raw material in styling hair cream, hair gel, and mousse. It can also be used for the cosmetics of skin moisturizing agents and the dispersants for grease based hair dying, also as foam stabilizers, and can improve the consistency of the shampoo. Insoluble PVP is the stabilizer of beer and juice which can improve its transparency, color, and flavor. Water-soluble polyamides Polyvinyl pyrrolidone (PVP) is a water soluble polyamide. Commercially available PVP is divided into four viscosity grades according to its press K value (Fikentscher K value): K-15, K-30, K-60, K-90, with the average molecular weight being 10,000, 40000,160000, and 360000, respectively. K value or molecular weight is an important factor which decides the various properties of PVP. Polyvinyl pyrrolidone (PVP) is dissolved in water, chlorinated solvents, alcohol, amine, nitro-paraffin and low molecular weight fatty acids, and is mutually soluble with most inorganic salts and a variety of resin; insoluble in acetone and ether. PVP used for the matrix of dropping pill matrix is odorless, tasteless, white to pale yellow waxy solid with the relative density being 1.062, and its 5% aqueous solution pH being 3 to 7. PVP is hygroscopic and of good thermal stability, and can be dissolved in various kinds of organic solvents, and has high melting point. Adding certain natural or synthetic polymers or organic compounds can effectively adjust the PVP's hygroscopicity and softness. PVP is not prone to have chemical reaction. Under normal storage conditions, dry PVP is quite stable. PVP has excellent physical inertia and biocompatibility and has not stimulation to skin, eyes no stimulation with no allergic reactions and being non-toxic. Because of the hydrogen bonding or complexation effect, PVP's viscosity is increased and this further inhibits the formation and growth of crystallized nuclei of drugs, making the drug being in the amorphous state. The dropping pill whose matrix is PVP can enhance the dissolution and bioavailability of poorly soluble drugs. In general, the greater the PVP amount, the higher dissolution and solubility of drug in the medium. Susana et al have studied the dissolution of the PVP solid dispersant of the slightly soluble drug albendazole. The increased amount of PVP (k30) can increase the dissolution rate and efficiency of drug inside the solid dispersant. Teresa et al have studied the dissolution of the poorly soluble drugs, flunarizine in PVP solid dispersant and obtained similar conclusion. PVP also found that the higher the content, the more significant increase in dissolution. IR has showed that flunarizine and PVP has no chemical reaction except in some cases that a best dissolution efficacy is obtained only in certain ratio between some drugs with the PVP. Tantishaiyakul et al has found that: when the ratio of piroxicam: PVP is 1:5 and 1:6, the dissolution of the solid dispersant is the largest with a 40 times as high as that of single drug within 5min. PVP can also be dissolved in another molten dropping pill matrix, such as polyethylene glycol (PEG), polyoxyethylene monostearate (S-40), poloxamer and stearyl acid, glyceryl monostearate, etc for making complex matrix. The above information is edited by the Chemicalbook of Dai Xiongfeng. Physical and chemical properties Commonly used PVP level in the cosmetic industry is K-30. Commercialized PVP is white and free flowing powder or solids with its content in the mass fraction of 20%, 30%, 45% and 50% aqueous solution. PVP is soluble in water and is hygroscopic with a moisture equilibrium being 1/3 of the relative humidity of the environment. Similar as the protein hydration action, each monomer associates with 0.5mol water.Chart 1 and Chart 2 lists the reference quality standard of various types of polyvinylpyrrolidone PVP: Food grade and pharmaceutical grade polyvinylpyrrolidone PVP Chart 1: Food grade and pharmaceutical grade polyvinylpyrrolidone PVP Cosmetics and industrial polyvinylpyrrolidone PVP (Luvikol K, BASF) Chart 2: Cosmetics and industrial polyvinylpyrrolidone PVP (Luvikol K, BASF) PVP is not easy to have chemical reaction. When stored at normal conditions, dry PVP is quite stable. Solution undergone mildew treatment is also stable. When heated in air to 150 °C or mixed with ammonium persulfate to heat at 90 °C for 30min, PVP will be exchanged to become a water-insoluble compound. In the presence of azo compound or a dichromate oxidizing agent, light will cause PVP solution to become gel. The co-heating of PVP solution with strong base (such as sodium silicate or trisodium phosphate) will generate precipitation. Many different compounds can generate complexes with PVP. For example, the complexes of PVP and iodine is very stable and have a good bactericidal effect and can reduce its toxicity; Adding the copolymers of the polyacrylic acid, tannic acid or methyl vinyl ether and maleic acid to the aqueous solution of PVP will generate insoluble complexes which are insoluble in water, alcohols and ketones. But when being treated with base for neutralize the poly-acid can reverse the reaction; complexation between PVP and toxins, drugs and toxic chemicals can reduce their toxicity; some kinds of dyes can also form a strong complex with PVP, which is the basis for using PVP as a dye bleaching agent. The use of polyvinylpyrrolidone In the early 1950s, older, with shellac and oil-based hairspray had been rapidly replaced by PVP sprays which are still widely used until now. It can form wet, transparent film on the hair which is shiny and has good lubrication effect. PVP has good compatibility with a variety of good propellant and also has corrosion resistance. It is widely used in hair styling, as the film former in combing products, as the creatinine and stabilizer of skin care lotions and creams, as the base stock material for eye and facial cosmetics and lipstick base, and also as hair dye dispersants and shampoo foam stabilizer. PVP has detoxification effect and can reduce the irritation effects of other preparation on the skin and eyes. It is also used as toothpaste detergents, gelling agents and antidotes. The main drawback of PVP is its sensitivity to moisture. However, this issue can be tackled by using its vinyl acetate copolymer in order to mitigate the effects of moisture and humidity. In addition, PVP also has wide application in the pharmaceutical, beverage and textile industries. Rheological properties of solutions Water and methanol is the preferred solvent of PVP. pH value has little effect on the viscosity of the aqueous solution of PVP, for example, at 25 °C, pH range: 0.1~10, aqueous solution of PVP K-30 with a mass fraction of 5% concentration has a viscosity of 2.3~2.4mPa • s; in concentrated hydrochloric acid, this is 4.96mPa • s. Effect of temperature on the viscosity of the PVP aqueous solution is also relatively not obvious. Un-cross-linked PVP solution is not particularly thixotropic unless under very high concentration and display a short relaxation time. The chart 3 below lists the viscosity of PVP K-30 in a variety of solvents. Viscosity of PVP K-30 in various organic solvents (w %) (At room temperature) Chart 3: Viscosity of PVP K-30 in various organic solvents (w %) (At room temperature) Reference: Edited by Binyi Qiu, "Compendium of cosmetic chemistry and technology" Volume 1 Beijing: China Light Industry Press, 1997. Compatibility Polyvinylpyrrolidone is mainly used as pharmaceutical excipient, blood compatibilizer, cosmetics thickening agents, latex stabilizers, and clarifying agent of beer brewing. Not matter whether in solution or in the form of film, PVP always has a high degree of compatibility. It has good compatibility with various kinds of inorganic salt solution, many natural and synthetic resins and other chemical compatibility. Examples of their compatibility are seen at chart 4 and Figure 5. The compatibility of PVP and some other substances in water and ethanol Chart 4: The compatibility of PVP and some other substances in water and ethanol The solubility and compatibility of PVP in various solvents Chart 5: The solubility and compatibility of PVP in various solvents Safety PVP is physiologically inert. Acute oral toxicity of PVP: LD50 > 100g/kg. It does not irritate the skin or eyes, do not cause skin allergies. A large number of long-term toxicology studies have confirmed that polyvinylpyrrolidone (PVP) can tolerate intraperitoneal, intramuscular, intravenous administration and parenteral applications. Subacute and chronic toxicity result was negative. Identification test Solubility: soluble in water, ethanol and chloroform and insoluble in ether. This is measured by the OT-42 method. Dichromate precipitation test: in 5 mL of2% sample solution, add 5 mL dilute hydrochloric acid solution (TS-117), further add 5 mL of water plus 2 mL of 10% potassium dichromate solution and 2ml. This should form an orange precipitate. Take 75 mg of cobalt nitrate and 300 mg of ammonium thiocyanate for being dissolved in 2ml of water; add 5 mL of 2% aqueous sample solution; after the mixing, add dilute hydrochloric acid test solution (TS-117) for acidification. This should form light blue precipitate. Take 5 mL of 2% sample solution; add 1 mL of 25% hydrochloric acid, 5 mL of 5% barium chloride and 1 mL 5% molybdenum tungsten phosphoric acid solution. This should generate a lot of white precipitate which gradually turns blue in the sunlight. The pH value of 5% sample solution should be 3.0 to 3.7. This is measured by conventional means. Adding a few drops of iodine test solution (TS-124) to 5 mL of 0.5% sample solution should produce a deep red color. Take 1 g of sample, add water to 10 ml as a suspension, add 0.1 mL of iodine test solution (TS-124), after mixing by shaking for 30s, iodine test solution should fade (to distinguish polyvinylpyrrolidone due to that polyvinylpyrrolidone can form red color). Add 1 mL of starch test solution (TS-235), after shaking and mixing, there should be no blue color formed. to produce blue. Content Analysis Estimated from the nitrogen content according to the following index of quality. Toxicity ADI 0~50 (FAO/WHO, 2001) LD50> 100g/kg (rat, oral). ADI does not make special provision (FAO/WHO, 2001). It is safe for food (FDA, §121.1110, §173.50, 2000). LD50:12g/kg (mice, abdominal injection). Limited use GB 2760-1996: beer GMP. Chemical Properties It is the cross-linked homopolymer of pure vinylpyrrolidone. It is hygroscopic and free-flowing white or off-white powder. It has a slight foul smell. It is insoluble in common solvents such as water, ethanol and ether. So its molecule weight range can't be measured. However, PVP has ability to form complex with various kinds of substances (such as "Hu" class substance which can lead to the discoloration of a variety of wines and beverages discoloration). Also it is easily to be removed after filtration because of its insolubility. Uses Clarifying agent; pigment stabilizer; colloidal stabilizer; It is mainly used for beer clarifying and quality stabilizing (reference amount 8~20g/100L, maintained for 24h and remove it by filtration), and can also be applied in combination with enzymes (protease) and protein adsorbents. It is also used to clarify the wine and as a stabilizer to prevent discoloration (reference amount 24~72g/100L). Clarifying agents; stabilizers; thickeners agent; tablet fillers; dispersants; PVP of molecular weight 360,000 are often used as the clarifying agent of beer, vinegar, and grape wine. Used as the fixing liquid for gas chromatography. It is used as a colloidal stabilizer and clarifying agent for beer clarification. Apply proper amount according the demands of production. It can be used for pharmacy, aquaculture, and livestock disinfectant for the sterilization of the skin and mucous. PolyFilterTM molecule has an amide bond for absorbing the hydroxyl groups located in polyphenol molecule to form hydrogen bonds, and therefore, can be used as the stabilizer of beer, fruit wine/grape wine, and drinking wine to extend their shelf life and improve the transparency, color and taste. The products have two specifications: disposable type and regeneration type. Disposable products are suitable for application by SMEs; renewable products demand the purchase of special filtration equipment; but since it is recyclable, it is suitable for large breweries for recycle application. In daily cosmetics, PVP and its copolymer has good dispersion property and filming property, and thus being able to be used as a setting lotion, hair spray and styling mousse, as opacifiers for hair care agents, as the stabilizer of shampoo foam, as wave styling agent and as the dispersants and affinity agents in hair dye. Adding PVP to cream, sunscreen, and hair removal agent can enhance wetting and lubricating effect. Taking advantage of the excellent properties of PVP such as surface activity, film-forming and non-irritating to the skin, no allergic reactions, etc., has broad prospects in its application in hair care and skin care products. Production method Its crude product comes from the polymerization of vinylpyrrolidone under basic catalyst or the existence of N, N'-divinyl amidine and further cross-inking reaction. Then use water, 5% acetic acid and 50% ethanol for reflux to until extract ≤50mg/kg (for over 3h). The 30% to 60% aqueous solution of the purified 1-vinyl-2-pyrrolidone, in the presence of ammonia or amines and also with hydrogen peroxide as the catalyst, has cross-linking and homo-polymerization reaction at a temperature of 50 °C and subject to further purification to obtain the final product. Chemical Properties Hygroscopic, white or yellowish-white powder or flakes. Chemical Properties Povidone occurs as a fine, white to creamy-white colored, odorless or almost odorless, hygroscopic powder. Povidones with K-values equal to or lower than 30 are manufactured by spray-drying and occur as spheres. Povidone K-90 and higher K-value povidones are manufactured by drum drying and occur as plates. Uses suitable for gene delivery Definition ChEBI: A vinyl polymer composed of repeating -CH2-CR- units where R is a 2-oxopyrrolidin-1-yl group. Production Methods Povidone is manufactured by the Reppe process. Acetylene and formaldehyde are reacted in the presence of a highly active copper acetylide catalyst to form butynediol, which is hydrogenated to butanediol and then cyclodehydrogenated to form butyrolactone. Pyrrolidone is produced by reacting butyrolactone with ammonia. This is followed by a vinylation reaction in which pyrrolidone and acetylene are reacted under pressure. The monomer, vinylpyrrolidone, is then polymerized in the presence of a combination of catalysts to produce povidone. brand name Kollidon CL (BASF); Kollidon CLM (BASF); Polyplasdone (International Specialty Products);Acu-dyne;Adapettes;Adsorbobase;Adsovbotear;Agent at 717;Albigen a;Aldacol q;Amiorel eritro;Amyderm s;Andrestrac 2-10;Anexa;B 7509;Betaisod;Bridine;Clinidine;Final step;Frepp/sepp;Ganex p 804;Ga-pvp-101;Gyno-bidex;Isoplasma;Jodoplex;K 115;Kollidon 17;Kollidon 25;Kollidon 30;Kollidon 90;Kollidon ce 50/50;Kollidon k 25;Kollidon k 30;Luviskol k 17;Luviskol k 25;Luviskol k 30;Luviskol k 90;Luvisteol;Medicort;Molycu;Mundidon;Neojodin;Oftan flurekain;Peragal st;Periston-n-toxobin;Pevidine;Plasmadone;Plasmoid;Plassint;Podiodine;Polyclar at;Polyclar h;Polyclar l;Polyplasdone xl;Polyvidone-escupient;Polyvinyl pyrrolidone;Povadyne;Povidone k 29-32;Pvp 50;Pvp0;Pvp-k 15;Pvp-k 25;Pvp-k 30;Pvp-k 60;Pvp-k 90;Pvp-macrose;Pvp-macrox;Rocmuth;Sd 13;Soft-care;Tears plus;Venostasin retard;Vetedine;Yodiplexin. World Health Organization (WHO) Polyvidone, a polymer of vinylpyrrolidinone, is an excipient used as a suspending and dispersing agent. Injectable preparations containing polymers with a molecular weight in the order of 12,000 have caused painful local granulomatous lesions. This has led to the withdrawal of polyvidone from such preparations in some countries. Polyvidone was formerly also used as a plasma expander but, because it was sequestered within the liver and spleen, this use has been discontinued. However, it remains widely used as a vehicle for ophthalmic preparations, and as the major component of artificial tears. General Description White powder. Compatible with a wide range of hydrophilic and hydrophobic resins. Air & Water Reactions Hygroscopic. Water soluble. Reactivity Profile Polyvinylpyrrolidone is a polymeric material and probably has low reactivity. Polyvinylpyrrolidone reacts as a weak base. Hazard Questionable carcinogen. Health Hazard SYMPTOMS: Polyvinylpyrrolidone may cause interstitial fibrosis in the lungs. Lesions regress when patient is no longer being exposed to the compound. Fire Hazard Flash point data for Polyvinylpyrrolidone are not available, but Polyvinylpyrrolidone is probably non-flammable. Pharmaceutical Applications Although povidone is used in a variety of pharmaceutical formulations, it is primarily used in solid-dosage forms. In tableting, povidone solutions are used as binders in wet-granulation processes.Povidone is also added to powder blends in the dry form and granulated in situ by the addition of water, alcohol, or hydroalcoholic solutions. Povidone is used as a solubilizer in oral and parenteral formulations, and has been shown to enhance dissolution of poorly soluble drugs from solid-dosage forms. Povidone solutions may also be used as coating agents or as binders when coating active pharmaceutical ingredients on a support such as sugar beads. Povidone is additionally used as a suspending, stabilizing, or viscosity-increasing agent in a number of topical and oral suspensions and solutions. The solubility of a number of poorly soluble active drugs may be increased by mixing with povidone. Special grades of pyrogen-free povidone are available and have been used in parenteral formulations; Contact allergens Polyvinylpyrrolidone is widely used as is in cosmetics such as hair care products and in medical products. It acts as iodophor in iodine-polyvinylpyrrolidone. PVP is an irritant and has been claimed as the allergen in some cases of dermatitis from iodine-polyvinylpyrrolidone (although iodine is more likely the hapten). It may cause type I contact urticaria or anaphylaxis. Safety Profile Mtldly toxic by intraperitoneal and intravenous routes. Questionable carcinogen. When heated to decomposition it emits toxic fumes of NOx. Safety Povidone has been used in pharmaceutical formulations for many years, being first used in the 1940s as a plasma expander, although it has now been superseded for this purpose by dextran. Povidone is widely used as an excipient, particularly in oral tablets and solutions. When consumed orally, povidone may be regarded as essentially nontoxic since it is not absorbed from the gastrointestinal tract or mucous membranes.Povidone additionally has no irritant effect on the skin and causes no sensitization. exists that povidone may accumulate in the organs of the body following intramuscular injection. A temporary acceptable daily intake for povidone has been set by the WHO at up to 25 mg/kg body-weight. (mouse, IP): 12 g/kg storage Povidone darkens to some extent on heating at 150°C, with a reduction in aqueous solubility. It is stable to a short cycle of heat exposure around 110-130°C; steam sterilization of an aqueous solution does not alter its properties. Aqueous solutions are susceptible to mold growth and consequently require the addition of suitable preservatives. Povidone may be stored under ordinary conditions without undergoing decomposition or degradation. However, since the powder is hygroscopic, it should be stored in an airtight container in a cool, dry place. Purification Methods Purify it by dialysis, and freeze-drying. Also by precipitation from CHCl3 solution by pouring into ether. Dry it in a vacuum over P2O5. For the crosslinked polymer purification is by boiling for 10minutes in 10% HCl and then washing with glass-distilled water until free from Cl ions. Finally, Cl ions are removed more readily by neutralising with KOH and continued washing. Incompatibilities Povidone is compatible in solution with a wide range of inorganic salts, natural and synthetic resins, and other chemicals. It forms molecular adducts in solution with sulfathiazole, sodium salicylate, salicylic acid, phenobarbital, tannin, and other compounds; see Section 18. The efficacy of some preservatives, e.g. thimerosal, may be adversely affected by the formation of complexes with povidone. Traditional High-Efficient Rheology Modifier Carbomer Efficient Rheology Modifier For Home Care Traditional Long-Flow Property Carbomer Improved Type - Easy To Disperse Carbomer Improved Type -Self-Wetting Carbomer Improved Type Carbomer Liquid Carbomer Pharmaceutical Grade Carbomer Home Care Carbomer High Carlity Traditional Carbomer Benzen Free Carbomer Homopolymer Of Vinylpyrrolidone NM-PVP K-30 Chemical Name: Homopolymer of Vinylpyrrolidone CTFA Name :Polyvinylpyrrolidone NM-PVP K-30 can dissolve in water and grain alcohol, isopropyl alcohol or chloroform, but not in acetone or diethyl ether. Have good absorption moisture, film-forming, complex ability. It is a high performance, versatile polymer widely used in pharmaceutical field, cosmetics field, beer, water treatment membrane, detergents, paints and other fields. Application 1. Pharma application: Used as binder for tablet and pellet, dissolving assistant for injection, flowing assistant capsule, dispersant for liquid medicine and pigment, stabilizer for enzyme and heat sensitive drug. 2. Cosmetic application: Used extensively in a wide range hair care, skin care &oral care products. The products are particularly suitable for formulation where viscosity modification and film forming properties are required. 3. Tech application: As surface coating agent, dispersing agent, thickener, binder, porogen in water treatment membrane ( hollow fiber m

PVP/VA Copolymer; Poly(1-vinylpyrrolidone-co-Vinyl Acetate); Polectron 845; Luviskol VA 28I; Vinyl acetate-vinylpyrrolidone polymer; Vinylpyrrolidinone-vinyl acetate polymer CAS NO: 25086-89-9

Povidone-Iodine is an iodophor solution containing a water-soluble complex of iodine and PVP K-90 (PVP) with broad microbicidal activity. Free iodine, slowly liberated from the polyvinylpyrrolidone iodine (PVPI) complex in solution, kills eukaryotic or prokaryotic cells through iodination of lipids and oxidation of cytoplasmic and membrane compounds. This agent exhibits a broad range of microbicidal activity against bacteria, fungi, protozoa, and viruses. Slow release of iodine from the PVPI complex in solution minimizes iodine toxicity towards mammalian cells.Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function. WHEN GIVEN PARENTERALLY, UNEXCRETED PARTICLES ARE PHAGOCYTIZED BY CELLS OF RETICULOENDOTHELIAL SYSTEM & DEPOSITED IN STORAGE SITES IN LIVER, SPLEEN, LUNG, BONE MARROW...In 12 nonpregnant women, total iodine, protein-bound iodine, inorganic iodine, and thyroxine values were measured in serum before and 15, 30, 45 or 60 minutes after a two-minute vaginal disinfection with povidone-iodine (Betadine). Only 15 minutes after application, serum iodine levels were raised and remained significantly elevated 30, 45 and 60 minutes after disinfection. Serum concentrations of total iodine and inorganic iodine were increased up to fivefold to 15-fold, respectively; during the relative short period of observation, thyroxine levels were not altered.The disposition of N-[14C]-vinyl-2-pyrrolidone has been studied in male Sprague-Dawley rats following a single iv injection. ...Up to 6 hr after dosing, the highest tissue concentrations of radioactivity were found in the liver and small intestines. By that time, about 19% of the dose had been excreted in bile, yet, by 12 hr, only about 0.4% had been excreted in feces while about 75% had been excreted in urine. Thus, there appeared to be substantial enterohepatic recirculation of biliary metabolites. Very small quantities of the administered material were excreted unchanged. In a single rat, 12% of the urinary radioactivity was present as acetic acid. Other metabolites were not identified.Following ingestion /1-vinyl-2-pyrrolidinone/ is mainly distributed in the liver and small intestine. It is partially excreted in the urine in an acetate form, but it is mostly (88%) combined with water-soluble acid compounds. Following iv injection, 14C-1-vinyl-2-pyrrolidinone was cleared from the blood with a half-life of about 2 hr. Unchanged /1-vinyl-2-pyrrolidinone/ accounted for <0.6% of the dose administered.The disposition of N-[14C-vinyl]-2-pyrrolidinone was studied in male Sprague-Dawley rats following a single iv injection. Plasma levels of the intact compound dropped rapidly within the first 6 hours after dosing... . Urinary excretion by 12 hours represented 74.9% of a 5 microCi dose while 18.7% was excreted into the bile by 6 hours. 14C-activity attributed to the intact compound was found to be <0.59% of the dose in the urine and <0.46% in the bile. Tissue distribution studies showed that the liver and small intestines and contents contained the highest accumulation of 14C-activity up to 6 hours after administration of N-[14C-vinyl]-2-pyrrolidinone. Urine analyses performed for metabolite elucidation indicated that 12% of the radioactivity dosed was incorporated into acetate and the major remaining portion in species which appeared to be water soluble acidic compounds.The toxic effects of vinylpyrrolidone /and/ vinylacetate (VP-VA) were examined in rats. Female Wistar-rats, under ether narcosis, were given endotracheally 0.5 mL of a standard solution of VP-VA (10 g in 15 mL of physiological sodium-chloride solution). Other rats received up to 7 times the 2 mL standard solution daily under the skin of the back; between 1.1 and 45.0 g/kg VP-VA were injected. The animals were sacrificed between 1 and 365 days following the application of the VP-VA solution. Tissues were stained and examined by electron microscopy. One to 2 days after endotracheal injection, the alveoli were closely packed with macrophages. Four to 6 months after the last injection, there was still VP-VA in the lungs with the attendent macrophages. Animals killed 1 yr after the last injection showed no VP-VA in the lungs. After sc injection, most of the VP-VA was stored in the spleen. There were occasional, large macrophages found in the interstitial tissue of the lung. During the 1 yr period of observation, there was no evidence of tumors or systemic disease.PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-90 100% Powder appears as a white powder. PVP K-90 is a component of Denhardt's Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution. PVP K-90 is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution. Available in several molecular weight grades, they are characterized by K-value, and used in a great variety of applications. PVP K-90 can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the lactam ring.High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.Dispersancy, where components in a mixture are uniformly distributed through the use of PVP K-90.Hydrophilicity, where the substantial water solubility of PVP K-90 is its dominant feature and frequently a factor along with other properties valuable to numerous applications.Adhesion, taking advantage of the higher molecular weight PVP K-90s formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques.PVP K-90 is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. acts as rheology modifier. is a highly adhesive tablet binder. stabilizes emulsion and structures liquid products. provides anti-soil redeposition, enzyme stabilization and dye transfer inhibition. functions as binder and protective coating for enzymes. provides surface shine enhancement. forms hard, transparent, glossy films.PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-90 100% Powder appears as a white powder. PVP K-90 is a component of Denhardt's Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution. PVP K-90 is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution. Available in several molecular weight grades, they are characterized by K-value, and used in a great variety of applications. PVP K-90 can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the lactam ring.High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.Dispersancy, where components in a mixture are uniformly distributed through the use of PVP K-90.Hydrophilicity, where the substantial water solubility of PVP K-90 is its dominant feature and frequently a factor along with other properties valuable to numerous applications.Adhesion, taking advantage of the higher molecular weight PVP K-90s formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques.PVP K-90 is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. acts as rheology modifier. is a highly adhesive tablet binder. stabilizes emulsion and structures liquid products. provides anti-soil redeposition, enzyme stabilization and dye transfer inhibition. functions as binder and protective coating for enzymes. provides surface shine enhancement. forms hard, transparent, glossy films.PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-90 100% Powder appears as a white powder. PVP K-90 is a component of Denhardt's Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution. PVP K-90 is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution. Available in several molecular weight grades, they are characterized by K-value, and used in a great variety of applications. PVP K-90 can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the lactam ring.High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.Dispersancy, where components in a mixture are uniformly distributed through the use of PVP K-90.Hydrophilicity, where the substantial water solubility of PVP K-90 is its dominant feature and frequently a factor along with other properties valuable to numerous applications.Adhesion, taking advantage of the higher molecular weight PVP K-90s formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques.PVP K-90 is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. acts as rheology modifier. is a highly adhesive tablet binder. stabilizes emulsion and structures liquid products. provides anti-soil redeposition, enzyme stabilization and dye transfer inhibition. functions as binder and protective coating for enzymes. provides surface shine enhancement. forms hard, transparent, glossy films. Povidone-Iodine is an iodophor solution containing a water-soluble complex of iodine and PVP K-90 (PVP) with broad microbicidal activity. Free iodine, slowly liberated from the polyvinylpyrrolidone iodine (PVPI) complex in solution, kills eukaryotic or prokaryotic cells through iodination of lipids and oxidation of cytoplasmic and membrane compounds. This agent exhibits a broad range of microbicidal activity against bacteria, fungi, protozoa, and viruses. Slow release of iodine from the PVPI complex in solution minimizes iodine toxicity towards mammalian cells.Synthetic or natural materials, other than DRUGS, that are used to replace or repair any body TISSUES or bodily function. WHEN GIVEN PARENTERALLY, UNEXCRETED PARTICLES ARE PHAGOCYTIZED BY CELLS OF RETICULOENDOTHELIAL SYSTEM & DEPOSITED IN STORAGE SITES IN LIVER, SPLEEN, LUNG, BONE MARROW...In 12 nonpregnant women, total iodine, protein-bound iodine, inorganic iodine, and thyroxine values were measured in serum before and 15, 30, 45 or 60 minutes after a two-minute vaginal disinfection with povidone-iodine (Betadine). Only 15 minutes after application, serum iodine levels were raised and remained significantly elevated 30, 45 and 60 minutes after disinfection. Serum concentrations of total iodine and inorganic iodine were increased up to fivefold to 15-fold, respectively; during the relative short period of observation, thyroxine levels were not altered.The disposition of N-[14C]-vinyl-2-pyrrolidone has been studied in male Sprague-Dawley rats following a single iv injection. ...Up to 6 hr after dosing, the highest tissue concentrations of radioactivity were found in the liver and small intestines. By that time, about 19% of the dose had been excreted in bile, yet, by 12 hr, only about 0.4% had been excreted in feces while about 75% had been excreted in urine. Thus, there appeared to be substantial enterohepatic recirculation of biliary metabolites. Very small quantities of the administered material were excreted unchanged. In a single rat, 12% of the urinary radioactivity was present as acetic acid. Other metabolites were not identified.Following ingestion /1-vinyl-2-pyrrolidinone/ is mainly distributed in the liver and small intestine. It is partially excreted in the urine in an acetate form, but it is mostly (88%) combined with water-soluble acid compounds. Following iv injection, 14C-1-vinyl-2-pyrrolidinone was cleared from the blood with a half-life of about 2 hr. Unchanged /1-vinyl-2-pyrrolidinone/ accounted for <0.6% of the dose administered.The disposition of N-[14C-vinyl]-2-pyrrolidinone was studied in male Sprague-Dawley rats following a single iv injection. Plasma levels of the intact compound dropped rapidly within the first 6 hours after dosing... . Urinary excretion by 12 hours represented 74.9% of a 5 microCi dose while 18.7% was excreted into the bile by 6 hours. 14C-activity attributed to the intact compound was found to be <0.59% of the dose in the urine and <0.46% in the bile. Tissue distribution studies showed that the liver and small intestines and contents contained the highest accumulation of 14C-activity up to 6 hours after administration of N-[14C-vinyl]-2-pyrrolidinone. Urine analyses performed for metabolite elucidation indicated that 12% of the radioactivity dosed was incorporated into acetate and the major remaining portion in species which appeared to be water soluble acidic compounds.The toxic effects of vinylpyrrolidone /and/ vinylacetate (VP-VA) were examined in rats. Female Wistar-rats, under ether narcosis, were given endotracheally 0.5 mL of a standard solution of VP-VA (10 g in 15 mL of physiological sodium-chloride solution). Other rats received up to 7 times the 2 mL standard solution daily under the skin of the back; between 1.1 and 45.0 g/kg VP-VA were injected. The animals were sacrificed between 1 and 365 days following the application of the VP-VA solution. Tissues were stained and examined by electron microscopy. One to 2 days after endotracheal injection, the alveoli were closely packed with macrophages. Four to 6 months after the last injection, there was still VP-VA in the lungs with the attendent macrophages. Animals killed 1 yr after the last injection showed no VP-VA in the lungs. After sc injection, most of the VP-VA was stored in the spleen. There were occasional, large macrophages found in the interstitial tissue of the lung. During the 1 yr period of observation, there was no evidence of tumors or systemic disease.PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-90 100% Powder appears as a white powder. PVP K-90 is a component of Denhardt's Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution. PVP K-90 is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution. Available in several molecular weight grades, they are characterized by K-value, and used in a great variety of applications. PVP K-90 can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the lactam ring.High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.Dispersancy, where components in a mixture are uniformly distributed through the use of PVP K-90.Hydrophilicity, where the substantial water solubility of PVP K-90 is its dominant feature and frequently a factor along with other properties valuable to numerous applications.Adhesion, taking advantage of the higher molecular weight PVP K-90s formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques.PVP K-90 is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. acts as rheology modifier. is a highly adhesive tablet binder. stabilizes emulsion and structures liquid products. provides anti-soil redeposition, enzyme stabilization and dye transfer inhibition. functions as binder and protective coating for enzymes. provides surface shine enhancement. forms hard, transparent, glossy films.PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-90 100% Powder appears as a white powder. PVP K-90 is a component of Denhardt's Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution. PVP K-90 is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution. Available in several molecular weight grades, they are characterized by K-value, and used in a great variety of applications. PVP K-90 can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the lactam ring.High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.Dispersancy, where components in a mixture are uniformly distributed through the use of PVP K-90.Hydrophilicity, where the substantial water solubility of PVP K-90 is its dominant feature and frequently a factor along with other properties valuable to numerous applications.Adhesion, taking advantage of the higher molecular weight PVP K-90s formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques.PVP K-90 is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. acts as rheology modifier. is a highly adhesive tablet binder. stabilizes emulsion and structures liquid products. provides anti-soil redeposition, enzyme stabilization and dye transfer inhibition. functions as binder and protective coating for enzymes. provides surface shine enhancement. forms hard, transparent, glossy films.PVP is used as a film former in hair styling products, PVP can also be used as an emulsion stabilizer in creams and lotions and as a dispersant for hair colorants. Additionally, pharmaceutical grade PVP can be used in toothpastes and mouthwashes. PVP K-90 100% Powder appears as a white powder. PVP K-90 is a component of Denhardt's Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution. PVP K-90 is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder or a clear aqueous solution. Available in several molecular weight grades, they are characterized by K-value, and used in a great variety of applications. PVP K-90 can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. Applications take advantage of one or more properties inherent in the polymer, typically due to the lactam ring.High polarity and the resultant propensity to form complexes with hydrogen donors, such as phenols and carboxylic acids, as well as anionic dyes and inorganic salts.Dispersancy, where components in a mixture are uniformly distributed through the use of PVP K-90.Hydrophilicity, where the substantial water solubility of PVP K-90 is its dominant feature and frequently a factor along with other properties valuable to numerous applications.Adhesion, taking advantage of the higher molecular weight PVP K-90s formulating in aqueous media, then evaporating sufficient water to generate a solid product for the desired application.Cohesivity, where cohesive strength is achieved through a variety of dry blending and granulation techniques.PVP K-90 is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. acts as rheology modifier. is a highly adhesive tablet binder. stabilizes emulsion and structures liquid products. provides anti-soil redeposition, enzyme stabilization and dye transfer inhibition. functions as binder and protective coating for enzymes. provides surface shine enhancement. forms hard, transparent, glossy films.

PVP VA 64 is a 6:4 linear random copolymer of N-vinylpyrrolidone and vinyl acetate.
The vinyl acetate component of PVP VA 64 reduces the hydrophilicity and glass transition temperature (Tg) compared to povidone homopolymers of similar molecular weight.
As a result, PVP VA 64 is the ultimate tablet binder that extends its excellent adhesive property in wet granulation, as well as in dry granulation and direct compression.

CAS: 25086-89-9
MF: C10H15NO3
MW: 197.23

Due to its spherical, hollow particle morphology and high plasticity, PVP VA 64 performs exceptionally well as a binder for direct compression.
In addition, a lower Tg makes PVP VA 64 an ideal polymer matrix for solid dispersions/solutions via hot melt extrusion, which enhances the dissolution of poorly soluble drug actives.
PVP VA 64 is used widely in pharmaceutical formulations and is generally regarded as nontoxic.
However, PVP VA 64 is moderately toxic by ingestion, producing gastric disturbances.
PVP VA 64 has no irritating or sensitizing effects on the skin.

A study was conducted to look at the carcinogenicity and chronic toxicity of PVP VA 64 (Kollidon VA 64) in Wistar rats and Beagle dogs.
The results of these studies demonstrated the absence of any significant toxicological findings of high dietary levels of copodivone in rats and dogs, resulting in noobserved- adverse-effect levels of 2800 mg/kg body-weight/day in rats and 2500 mg/kg body-weight/day in dogs, the highest doses tested.

PVP VA 64 copolymer functions as a binder, film former and hair fixative in cosmetic products.
PVP VA 64 is a more important ingredient from a formulation than a skincare standpoint.
As a binding agent, PVP VA 64 helps to bind or hold together the ingredients of a cosmetic product in the form of a compressed cake or tablet of a product.

Ingredients in dry form are mixed using a minimal amount of binder and then compressed to the desired effect.
This method prevents other ingredients in the product from breaking down.
As a film-forming agent, when applied to hair or skin, they form a continuous, cohesive, flexible layer.

This layer/film has water retention properties that leave a silky smooth effect on the skin. PVP VA 64 is also used in hair sprays and gels.
When used, PVP VA 64 forms a thin layer or film on the surface of the hair.
Considering its structure, PVP VA 64 also has several chemical groups that form temporary bonds that not only help to form a film, but also help to attach to the hair shaft and maintain the hairstyle.
PVP VA 64 prevents the hair from absorbing moisture and helps you maintain the style.
PVP VA 64 is used in formulas for styling products and other hair care products.

Benefits:
Suitability for use in direct compression, dry granulation, wet granulation, hot melt extrusion, and film coating,
Good flowability,
Large surface area due to hollow particle morphology – enhances particle bonding and good compressibility,
Ideal glass transition temperature (Tg) for hot melt extrusion.

PVP VA 64 Chemical Properties
Density: 1.27 g/mL at 25 °C(lit.)
Refractive index: 1.4300 to 1.4380
Fp: 72 °F
Solubility: Greater than 10% solubility in 1,4-butanediol, glycerol, butanol, chloroform, dichloromethane, ethanol (95%), glycerol, methanol, polyethylene glycol 400, propan-2-ol, propanol, propylene glycol, and water.
Less than 1% solubility in cyclohexane, diethyl ether, liquid paraffin, and pentane.
Form: powder
Color: White
Stability: Stable. Combustible, especially in powdered form. Incompatible with strong oxidising agents, strong reducing agents.
LogP: 0.370 (est)
EPA Substance Registry System: PVP VA 64 (25086-89-9)

PVP VA 64 is a white to yellowish-white amorphous powder.
PVP VA 64 is typically spray-dried with a relatively fine particle size.
PVP VA 64 has a slight odor and a faint taste.

Uses
PVP VA 64 is a water-soluble polymer used to improve the uptake and drug loading of various pharmaceutical agents, including contraceptive patches.

The main raw materials of cosmetics are used for hair gel, mousse, shampoo, etc., as well as surfactants, medicine and other industries.
PVP VA 64 mainly used as water-soluble adhesives and dry adhesives in granulation and direct tabletting technology, as film-forming materials in film coating, and as pore forming materials in flavoring agents.
PVP VA 64 is applied to sugar coating to prevent lobes, and the bottom coating is used to prevent moisture.

PVP VA 64 copolymer series products are mainly used as film forming agents and shaping agents in the field of cosmetics, especially in hair spray, hair spray, mousse and shampoo series products.
They play an important role as film-forming agents and hair styling agents.
If they are used in conjunction with PVP K30, they will enhance their use effect.

Production Methods
PVP VA 64 is manufactured by free-radical polymerization of vinylpyrrolidone and vinyl acetate in a ratio of 6 : 4.
The synthesis is conducted in an organic solvent owing to the insolubility of vinyl acetate in water.

Pharmaceutical Applications
PVP VA 64 is used as a tablet binder, a film-former, and as part of the matrix material used in controlled-release formulations.
In tableting, PVP VA 64 can be used as a binder for direct compression and as a binder in wet granulation.
PVP VA 64 is often added to coating solutions as a film-forming agent.
PVP VA 64 provides good adhesion, elasticity, and hardness, and can be used as a moisture barrier.

Synonyms
25086-89-9
Polectron 845
Luviskol VA 28I
Luviskol VA 37E
Luviskol VA 64
Kolima 10
Kolima 35
ethenyl acetate;1-ethenylpyrrolidin-2-one
Gantron S 860
PVP-VA
Ganex E 535
GAF-S 630
Luviskol VA 281
Luviskol VA 28 I
Luviskol VA 37 E
I 535
I 635
I 735
S 630
MFCD00134018
Luviskol VA-64
SCHEMBL29127
Copovidone (Technical Grade)
vinylpyrrolidone/vinyl acetate
Vinyl Pyrrolidone/Vinyl Acetate
N-vinylpyrrolidone/vinyl acetate
1-vinylpyrrolidone vinyl acetate
BCP31918
NSC114023
NSC114024
NSC114025
NSC114026
AKOS015898247
NSC-114023
NSC-114024
NSC-114025
NSC-114026
1-ethenylpyrrolidin-2-one; ethenyl acetate
ethenyl ethanoate; 1-ethenylpyrrolidin-2-one
FT-0659810
A817635
acetic acid ethenyl ester; 1-ethenyl-2-pyrrolidinone
733045-73-3

PVP VA 64 is a 6:4 linear random copolymer of N-vinylpyrrolidone and vinyl acetate.
The vinyl acetate component of PVP VA 64 reduces the hydrophilicity and glass transition temperature (Tg) compared to povidone homopolymers of similar molecular weight.
As a result, PVP VA 64 is the ultimate tablet binder that extends its excellent adhesive property in wet granulation, as well as in dry granulation and direct compression.

CAS: 25086-89-9
MF: C10H15NO3
MW: 197.23

Due to its spherical, hollow particle morphology and high plasticity, PVP VA 64 performs exceptionally well as a binder for direct compression.
In addition, a lower Tg makes PVP VA 64 an ideal polymer matrix for solid dispersions/solutions via hot melt extrusion, which enhances the dissolution of poorly soluble drug actives.
PVP VA 64 is used widely in pharmaceutical formulations and is generally regarded as nontoxic.
However, PVP VA 64 is moderately toxic by ingestion, producing gastric disturbances.
PVP VA 64 has no irritating or sensitizing effects on the skin.

A study was conducted to look at the carcinogenicity and chronic toxicity of PVP VA 64 (Kollidon VA 64) in Wistar rats and Beagle dogs.
The results of these studies demonstrated the absence of any significant toxicological findings of high dietary levels of copodivone in rats and dogs, resulting in noobserved- adverse-effect levels of 2800 mg/kg body-weight/day in rats and 2500 mg/kg body-weight/day in dogs, the highest doses tested.

PVP VA 64 copolymer functions as a binder, film former and hair fixative in cosmetic products.
PVP VA 64 is a more important ingredient from a formulation than a skincare standpoint.
As a binding agent, PVP VA 64 helps to bind or hold together the ingredients of a cosmetic product in the form of a compressed cake or tablet of a product.

Ingredients in dry form are mixed using a minimal amount of binder and then compressed to the desired effect.
This method prevents other ingredients in the product from breaking down.
As a film-forming agent, when applied to hair or skin, they form a continuous, cohesive, flexible layer.

This layer/film has water retention properties that leave a silky smooth effect on the skin. PVP VA 64 is also used in hair sprays and gels.
When used, PVP VA 64 forms a thin layer or film on the surface of the hair.
Considering its structure, PVP VA 64 also has several chemical groups that form temporary bonds that not only help to form a film, but also help to attach to the hair shaft and maintain the hairstyle.
PVP VA 64 prevents the hair from absorbing moisture and helps you maintain the style.
PVP VA 64 is used in formulas for styling products and other hair care products.

Benefits:
Suitability for use in direct compression, dry granulation, wet granulation, hot melt extrusion, and film coating,
Good flowability,
Large surface area due to hollow particle morphology – enhances particle bonding and good compressibility,
Ideal glass transition temperature (Tg) for hot melt extrusion.

PVP VA 64 Chemical Properties
Density: 1.27 g/mL at 25 °C(lit.)
Refractive index: 1.4300 to 1.4380
Fp: 72 °F
Solubility: Greater than 10% solubility in 1,4-butanediol, glycerol, butanol, chloroform, dichloromethane, ethanol (95%), glycerol, methanol, polyethylene glycol 400, propan-2-ol, propanol, propylene glycol, and water.
Less than 1% solubility in cyclohexane, diethyl ether, liquid paraffin, and pentane.
Form: powder
Color: White
Stability: Stable. Combustible, especially in powdered form. Incompatible with strong oxidising agents, strong reducing agents.
LogP: 0.370 (est)
EPA Substance Registry System: PVP VA 64 (25086-89-9)

PVP VA 64 is a white to yellowish-white amorphous powder.
PVP VA 64 is typically spray-dried with a relatively fine particle size.
PVP VA 64 has a slight odor and a faint taste.

Uses
PVP VA 64 is a water-soluble polymer used to improve the uptake and drug loading of various pharmaceutical agents, including contraceptive patches.

The main raw materials of cosmetics are used for hair gel, mousse, shampoo, etc., as well as surfactants, medicine and other industries.
PVP VA 64 mainly used as water-soluble adhesives and dry adhesives in granulation and direct tabletting technology, as film-forming materials in film coating, and as pore forming materials in flavoring agents.
PVP VA 64 is applied to sugar coating to prevent lobes, and the bottom coating is used to prevent moisture.

PVP VA 64 copolymer series products are mainly used as film forming agents and shaping agents in the field of cosmetics, especially in hair spray, hair spray, mousse and shampoo series products.
They play an important role as film-forming agents and hair styling agents.
If they are used in conjunction with PVP K30, they will enhance their use effect.

Production Methods
PVP VA 64 is manufactured by free-radical polymerization of vinylpyrrolidone and vinyl acetate in a ratio of 6 : 4.
The synthesis is conducted in an organic solvent owing to the insolubility of vinyl acetate in water.

Pharmaceutical Applications
PVP VA 64 is used as a tablet binder, a film-former, and as part of the matrix material used in controlled-release formulations.
In tableting, PVP VA 64 can be used as a binder for direct compression and as a binder in wet granulation.
PVP VA 64 is often added to coating solutions as a film-forming agent.
PVP VA 64 provides good adhesion, elasticity, and hardness, and can be used as a moisture barrier.

Synonyms
25086-89-9
Polectron 845
Luviskol VA 28I
Luviskol VA 37E
Luviskol VA 64
Kolima 10
Kolima 35
ethenyl acetate;1-ethenylpyrrolidin-2-one
Gantron S 860
PVP-VA
Ganex E 535
GAF-S 630
Luviskol VA 281
Luviskol VA 28 I
Luviskol VA 37 E
I 535
I 635
I 735
S 630
MFCD00134018
Luviskol VA-64
SCHEMBL29127
Copovidone (Technical Grade)
vinylpyrrolidone/vinyl acetate
Vinyl Pyrrolidone/Vinyl Acetate
N-vinylpyrrolidone/vinyl acetate
1-vinylpyrrolidone vinyl acetate
BCP31918
NSC114023
NSC114024
NSC114025
NSC114026
AKOS015898247
NSC-114023
NSC-114024
NSC-114025
NSC-114026
1-ethenylpyrrolidin-2-one; ethenyl acetate
ethenyl ethanoate; 1-ethenylpyrrolidin-2-one
FT-0659810
A817635
acetic acid ethenyl ester; 1-ethenyl-2-pyrrolidinone
733045-73-3

SYNONYMS acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone;ethenyl acetate;1-ethenylpyrrolidin-2-one;poly(1-vinyl pyrrolidone-co-vinyl acetate) CAS NO: 25086-89-9

DESCRIPTION:
PVP/VA 64 is a 6:4 linear random copolymer of N-vinylpyrrolidone and vinyl acetate.
The vinyl acetate component of PVP/VA 64 reduces the hydrophilicity and glass transition temperature (Tg) compared to povidone homopolymers of similar molecular weight.
As a result, PVP/VA 64 is the ultimate tablet binder that extends its excellent adhesive property in wet granulation, as well as in dry granulation and direct compression.

CAS-No: 25086-89-9
INCI name: VP/VA Copolymer
Molecular Formula: (C6H9NO.C4H6O2)x

CHEMICAL AND PHYSICAL PROPERTIES OF PVP/VA 64:
Appearance : White – Cream Powder
K value(1% in ethanol): 26.0-34.0
Vinyl pyrrolidone: 60
Vinyl acetate: 40
pH (10% solution) 4-7
Solids content: 95%
Versatile film-formers for formulating of hair styling products.
Properties and differentiation are determined by the VP/VAratio in the polymer.
The series includes alcoholic (Ethanol, Isopropanol), aqueous and powder products.
•Medium to strong hold; Nonionic, no neutralization required
•Water-soluble or dispersable; Easy to wash out
•Non-forming; Easy to handle; Easy to comb out
•Compatible with ionic (anionic as well as cationic) additives
•Makes the hair shiny; Propane/butane compatibility 20-45%
•DME compatibility>70%

PVP/VA 64 is an easy-to-use aqueous solution that is compatible with carbomers, and is particularly suitable for alcohol-free formulations, forming a clear solution in water.
Due to its spherical, hollow particle morphology and high plasticity, PVP/VA 64 performs exceptionally well as a binder for direct compression.
In addition, a lower Tg makes PVP/VA 64 an ideal polymer matrix for solid dispersions/solutions via hot melt extrusion, which enhances the dissolution of poorly soluble drug actives.

PVP/VA 64 is a copolymer of vinylpyrrolidone with vinyl acetate in an an easy-to-use aqueous solution.
PVP/VA 64 is preserved with 0.05% max. dodecyl trimethyl ammonium chloride.
PVP/VA 64 is an excellent film-former and hair styling agent.

VP/VA copolymer.
PVP/VA 64 Acts as a film-forming agent and fixative in hair care.
PVP/VA 64 Is a copolymer of 1-vinyl-2-pyrrolidone & vinyl acetate in ratio of 60:40 in the form of powder.
PVP/VA 64 is Suitable for hair sprays and hair set lotion.

BENEFITS OF PVP/VA 64:
PVP/VA 64 is Suitable for use in direct compression, dry granulation, wet granulation, hot melt extrusion, and film coating.
PVP/VA 64 has Good flowability
PVP/VA 64 has Large surface area due to hollow particle morphology – enhances particle bonding and good compressibility
PVP/VA 64 has Ideal glass transition temperature (Tg) for hot melt extrusion.


FUNCTIONS OF PVP/VA 64:
• Binding.
• Film forming.
• Hair fixing.
• Viscosity controlling.


APPLICATIONS OF PVP/VA 64:
OF PVP/VA 64 İS Used in hair care like aerosol sprays, non-aerosol products, liquid hair setting products, gels and mousses.

RECOMMENDED DOSAGE:
The following concentrations are recommended (solids):
˗ Aerosol hair spray 2 - 6%
˗ Pump spray 3 - 7%
˗ Setting lotions 1 - 5%
˗ Setting mousse 1 - 5%
˗ Gels 1 - 5%
˗ Hair waxes 1 - 5%

STORAGE OF OF PVP/VA 64:
Store at a cool, dry and well ventilated place.

SAFETY INFORMATION ABOUT PVP/VA 64:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.

Poly(1-vinylpyrrolidone-co-vinyl acetate); Copovidone; Poly(1-vinylpyrrolidone-co-Vinyl Acetate); Vinyl acetate-vinylpyrrolidone copolymer; PVP/VA Copolymer; Vinyl acetate-vinylpyrrolidinone polymer; Vinylpyrrolidinone-vinyl acetate polymer;

DESCRIPTION:
PVP/VA Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor.
So PVP/VA Copolymer is very common in most Hairsprays but also found in gel’s, wax’s, pomades and styling creams.
PVP/VA Copolymer is a synthetic ingredient that is derived from petroleum.

CAS NO.: 25086-89-9
Molecular Weight: 197.23415000
Formula:(C6H9NO) x (C4H6O2)y
CTFA NOMENCLATURE: PVP/VA copolymer


CHEMICAL AND PHYSICAL PROPERTIES OF PVP/VA COPOLYMER:
Solubility: Water (Heats accelerates hydration)
Use rate: 0.5 – 6.0% (Recommended use rate 3.0 – 5.0% for gels, creams, mousses and styling lotions)
Temperature tolerance: Avoid temperatures above 80°C
pH Stability: 4.0 – 7.0
Appearance: white to slightly yellowish, fine to coarse grained powder.
Assay: 60% VP (vinylpyrrolidone) / 40% VA (vinyl acetate) is available in powder form.
Storage: Store in a cool, dark, and dry place
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.95800 @ 25.00 °C.
Boiling Point: 217.60 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.132000 mmHg @ 25.00 °C. (est)
Flash Point: 72.00 °F. TCC ( 22.22 °C. )
logP (o/w): 0.370 (est)

PVP/VA (Also known as VP/VA), is a film forming agent that offers a strong, stiff hold in hair care.
PVP/VA Copolymer offers curl retention in high humidity.
PVP/VA Copolymer forms transparent, flexible, and breathable films

PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s.
PVP/VA Copolymer worked as a hairspray because it was soluble in water.
This meant PVP/VA Copolymer could be rinsed out when you wash your hair.
PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties.

PVP/VA Copolymer was fixed with the help of another polymer, a silicone called polydimethylsiloxane.
To understand how this silicone made a better hairspray, it helps to understand how the hairsprayworks in the first place.
When you spray PVP/VA Copolymer on, the polyvinylpyrrolidone forms a thin coating on the hair.
This coating is stiff and keeps the hair from moving around.
FEATURES OF PVP/VA COPOLYMER:
• Excellent curl retention
• Strong hold
• Transparency
• Anti-static
• Binding
• Emulsion stabilizing
• Film forming
• 60% VP (vinylpyrrolidone) / 40% VA (vinyl acetate) is available in powder form.


Pvp/va polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals.
Polyvinylpyrrolidone/vinyl acetate (pvp/va) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone.

Pvp/va copolymers are available as white powders or clear solutions in ethanol, isopropanol and water.
Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol.
The pvp/va copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions.


CHARACTERS:
In the form of powder, PVP/VA Copolymer is 50% aqueous solution or alcohol solution..
PVP/VA Copolymer is Able to form stiff, bright and washable film.
PVP/VA Copolymer is Soluble in most common organic solvents.

APPLICATIONS OF PVP/VA COPOLYMER:
PVP/VA Copolymer is used in Film-formers and stiffeners in hair care products.
PVP/VA Copolymer is used as Film formers in skin care preparations, suitable for eye and face dressings.

PVP/VA Copolymer is used as Rewettable Adhesives and adhesives for paper.
PVP/VA Copolymer is used as Thickeners and protective colloids for printing inks.
PVP/VA Copolymer is used as Dispersants and stabilizers for all kinds of suspensions and emulsions.

PVP/VA Copolymer is used in Hairsprays, mousses, coloring products, mousses, gels, styling lotions and conditioners.

What is PVP/VA COPOLYMER used for?
PVP/VA Copolymer has a number of benefits to offer in the world of cosmetics and personal care.
PVP/VA Copolymer can mainly be found in hair care products, followed by cosmetics and a few skin care products.

Skin care:
PVP/VA Copolymer is responsible for forming a thin layer on the skin that feels smooth to the touch and makes the surface look flawless.
PVP/VA Copolymer also retains moisture on the skin and doesn't allow it to run dry for longer durations of time.

Hair care:
PVP/VA Copolymer is mainly used in hair care products for hair setting.
PVP/VA Copolymer does not allow the shafts to absorb any further moisture and thus lose any styling done on them.
PVP/VA Copolymer also forms a thin coat on hair that helps them retain its shape.

Decorative cosmetics:
PVP/VA Copolymer is also added to cosmetic products like nail polish and mascara because it dries up to form a film that inhibits the surface from absorbing any moisture and thus keeps it styled impeccably.


ORIGIN OF PVP/VA COPOLYMER:
PVP/VA Copolymer is made by the monomers of vinylpyrrolidone and vinyl acetate.
PVP/VA Copolymer appears as a white free-flowing powder and is the result of very small chemical compounds combining to form a large molecule.


WHAT DOES PVP/VA COPOLYMER DO IN A FORMULATION?
• Film forming
• Hair fixing
• Moisturising

SAFETY PROFILE OF PVP/VA COPOLYMER:
PVP/VA Copolymer has been termed safe for use under the prescribed concentrations - any higher than that can cause side effects like irritation to the skin and scalp.
A patch test should be done before full usage.
Further, PVP/VA Copolymer is vegan.


SAFETY INFORMATION ABOUT PVP/VA COPOLYMER:

First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.

DESCRIPTION:
PVP/VA Copolymer is a film former produced by the free-radical polymerization on monomers in 70/30 VP/VA ratio.
PVP/VA Copolymer is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water.

CAS: 25086-89-9
European Community (EC) Number: 607-540-1
IUPAC Name: ethenyl acetate;1-ethenylpyrrolidin-2-one
Molecular Formula: C10H15NO3


SYNONYMS OF PVP/VA COPOLYMER:

Copovidone,Kollidon VA64,poly(V-co-V-Ac),poly(vinyl pyrrolidone-co-vinyl acetate),poly(vinylpyrrolidone-co-vinyl-acetate),polyvidone-vinylacetate 64,PVP VA64,PVP-VA,PVPVA 64,25086-89-9,PVP-VA,Polectron 845,Luviskol VA 28I,Luviskol VA 37E,Luviskol VA 64,Kolima 10,Kolima 35,ethenyl acetate;1-ethenylpyrrolidin-2-one,Gantron S 860,Ganex E 535,GAF-S 630,Luviskol VA 281,Luviskol VA 28 I,Luviskol VA 37 E,I 535,I 635,I 735,S 630,MFCD00134018,Copovidone (Technical Grade),Luviskol VA-64,SCHEMBL29127,vinylpyrrolidone/vinyl acetate,Vinyl Pyrrolidone/Vinyl Acetate,N-vinylpyrrolidone/vinyl acetate,1-vinylpyrrolidone vinyl acetate,FYUWIEKAVLOHSE-UHFFFAOYSA-N,BCP31918,NSC114023,NSC114024,NSC114025,NSC114026,AKOS015898247,NSC-114023,NSC-114024,NSC-114025,NSC-114026,1-ethenylpyrrolidin-2-one; ethenyl acetate,ethenyl ethanoate; 1-ethenylpyrrolidin-2-one,FT-0659810,A817635,acetic acid ethenyl ester; 1-ethenyl-2-pyrrolidinone,733045-73-3



PVP/VA Copolymer acts as a film forming agent.
PVP/VA Copolymer forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal.
PVP/VA Copolymer offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility.

PVP/VA Copolymer finds application in formulating hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers.
PVP/VA Copolymer is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in ethanol.
PVP/VA Copolymer is produced by the free-radical polymerization of monomers in the ratio of 70/30 (VP/VA).


PVP/VA Copolymer is a film forming ingredient that works well in both skin/hair care products and cosmetics.
PVP/VA Copolymer forms a film on the surface to trap and retain moisture for longer durations.

PVP/VA Copolymer is found primarily in most hair care products, mascaras, nail polishes and also some skin care products.
The full form of VP/VA Copolymer is vinylpyrrolidone/vinyl acetate copolymer, which appears as a white powder in its raw form.



FEATURES & BENEFITS OF PVP/VA COPOLYMER:
PVP/VA Copolymer is Strong, stiff hold
PVP/VA Copolymer has Enhanced high humidity curl retention

PVP/VA Copolymer is has Good propellant compatibility
PVP/VA Copolymer is Vegan suitable


CHEMICAL AND PHYSICAL PROPERTIES OF PVP/VA COPOLYMER:
Form: Aqueous viscous liquid
VP/VA Ratio: 70/30
50% solution in water
Color (APHA) - as is: 80 max.
K-Value (1% in EtOH): 25-34
Use Level: 0.5 - 6.0% solids
Primary Chemistry: VP/VA Copolymer
Molecular Weight
197.23 g/mol
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
3
Exact Mass
197.10519334 g/mol
Monoisotopic Mass
197.10519334 g/mol
Topological Polar Surface Area
46.6Ų
Heavy Atom Count
14
Formal Charge
0
Complexity
186
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes
SAFETY INFORMATION ABOUT PVP/VA COPOLYMER:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product

PVP/VA I-535 (Polyvinylpyrrolidone Vinyl Acetate) VP/VA Copolymer. PVP-VA I-535 acts as a film forming agent. PVP-VA I-535 is produced by the free-radical polymerization of monomers in the ratio of 50/50 (VP/VA). Shows good propellant compatibility. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. PVP-VA I-535 finds application in formulating hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. PVP-VA I-535 offers strong & stiff hold, enhanced high humidity curl retention. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is a film former produced by the free-radical polymerization on monomers in 70/30 VP/VA ratio. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. PVP/VA W-Series copolymers are linear, random copolymers produced by the free-radical polymerization of the monomers varying from 30/70 to 40/60 vinyl acetate (VA) to vinylpyrrolidone (VP), supplied in water. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. What is PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) Copolymer? PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. Ashland offers formulators a series of vinylpyrrolidone/vinyl acetate copolymers. Members of the PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymer series serve as primary film formers in a variety of products demanding different degrees of water resistance. These copolymers feature specific affinity for hair, skin and smooth surfaces such as wood, glass, paper, and metal, yet do not require solvents for removal. The advantages of using PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties • E = ethanol (EtOH), I = isopropanol, W = water, S = solid The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E and I copolymer Series To fit many application areas, the E and I series of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) S copolymer PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) S-630 copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W copolymers PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-735 copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-735 copolymer, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-535 copolymer and PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E- 335 copolymer. In general, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymer is less hygroscopic than PVP. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) S-630 copolymer is used as a binder to allow the aqueous processing of photoresists. Storage and handling PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E- and I-series To fit more application areas, the E- and I-series of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W copolymers PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-735 is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-735, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-535 and PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-335. In general, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is less hygroscopic than PVP. Abstract In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate), N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) used in industrial, specialty and imaging coatings, printing inks and paints. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene.[2] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives.[2] Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone.[1] What is PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) Copolymer? PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. (See image below) Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E and I copolymer Series To fit many application areas, the E and I series of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-735, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. Storage and handling PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E- and I-series To fit more application areas, the E- and I-series of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-735, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W copolymers PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-735 is a 70/30 copolymer of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) and vinyl acetate supplied as a 50% solution in water. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) W-735 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-735, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-535 and PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) E-335. In general, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is less hygroscopic than PVP. Uses Medical PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used as a binder in many pharmaceutical tablets;[2] it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.[3] The long-term effects of crospovidone or povidone within the lung are unknown.) PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.[4] This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.[5] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Technical PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as an adhesive in glue stick and hot-melt adhesives PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as an emulsifier and disintegrant for solution polymerization PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in increase resolution in photoresists for cathode ray tubes (CRT)[9] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a thickening agent in tooth whitening gels[10] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as an additive to Doro's RNA extraction buffer[citation needed] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a liquid-phase dispersion enhancing agent in DOSY NMR [11] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly[12] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is used in as a stabilizing agent in all inorganic solar cells[13] Other uses PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions.[14][15] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is useful for making an aqueous mounting medium.[16] PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production.[17] Safety of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses,[18] and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) component of the solution.[19] A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP.[20] In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP.[21] Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) instead.[22][23] Properties of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol,[24] as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin).[25] When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. A 2014 study found fluorescent properties of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) and its oxidized hydrolyzate. History of PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production. VP/VA Copolymer. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is a film former. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is produced by the free-radical polymerization of monomers in the ratio of 70/30 (VP/VA). PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)) copolymer in water. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) is a film former produced by the free-radical polymerization on monomers in 70/30 VP/VA ratio. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. PVP/VA W-Series copolymers are linear, random copolymers produced by the free-radical polymerization of the monomers varying from 30/70 to 40/60 vinyl acetate (VA) to vinylpyrrolidone (VP), supplied in water. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate)) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA I-535 (polyvinylpyrrolidone vinyl acetate) copolymers

Saç jölesi ve spreylerinde sertleştirici polimer. Saç jölesi (%10-15), Spreylerde (%8-20)

PVP/VA W-635 VP/VA Copolymer. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is a film former. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is produced by the free-radical polymerization of monomers in the ratio of 70/30 (VP/VA). PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) ) copolymer in water. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is a film former produced by the free-radical polymerization on monomers in 70/30 VP/VA ratio. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. PVP/VA W-Series copolymers are linear, random copolymers produced by the free-radical polymerization of the monomers varying from 30/70 to 40/60 vinyl acetate (VA) to vinylpyrrolidone (VP), supplied in water. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. What is PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) Copolymer? PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. Ashland offers formulators a series of vinylpyrrolidone/vinyl acetate copolymers. Members of the PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymer series serve as primary film formers in a variety of products demanding different degrees of water resistance. These copolymers feature specific affinity for hair, skin and smooth surfaces such as wood, glass, paper, and metal, yet do not require solvents for removal. The advantages of using PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties • E = ethanol (EtOH), I = isopropanol, W = water, S = solid The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E and I copolymer Series To fit many application areas, the E and I series of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) S copolymer PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) S-630 copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W copolymers PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-735 copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-735 copolymer, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-535 copolymer and PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E- 335 copolymer. In general, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymer is less hygroscopic than PVP. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) S-630 copolymer is used as a binder to allow the aqueous processing of photoresists. Storage and handling PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E- and I-series To fit more application areas, the E- and I-series of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W copolymers PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-735 is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-735, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-535 and PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-335. In general, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is less hygroscopic than PVP. Abstract In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) ) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) , N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) used in industrial, specialty and imaging coatings, printing inks and paints. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene.[2] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives.[2] Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone.[1] What is PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) Copolymer? PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. (See image below) Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E and I copolymer Series To fit many application areas, the E and I series of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-735, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. Storage and handling PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) ) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E- and I-series To fit more application areas, the E- and I-series of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-735, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W copolymers PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-735 is a 70/30 copolymer of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) and vinyl acetate supplied as a 50% solution in water. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) W-735 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-735, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-535 and PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) E-335. In general, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is less hygroscopic than PVP. Uses Medical PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used as a binder in many pharmaceutical tablets;[2] it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.[3] The long-term effects of crospovidone or povidone within the lung are unknown.) PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.[4] This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.[5] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Technical PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as an adhesive in glue stick and hot-melt adhesives PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as an emulsifier and disintegrant for solution polymerization PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in increase resolution in photoresists for cathode ray tubes (CRT)[9] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a thickening agent in tooth whitening gels[10] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as an additive to Doro's RNA extraction buffer[citation needed] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a liquid-phase dispersion enhancing agent in DOSY NMR [11] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly[12] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is used in as a stabilizing agent in all inorganic solar cells[13] Other uses PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions.[14][15] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is useful for making an aqueous mounting medium.[16] PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production.[17] Safety of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses,[18] and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) component of the solution.[19] A woman, who had previously experienced urticaria (hives) from various hair products, later found to contain PVP, had an anaphylactic response after povidone-iodine solution was applied internally. She was found to be allergic to PVP.[20] In another case, a man experiencing anaphylaxis after taking acetaminophen tablets orally was found to be allergic to PVP.[21] Povidone is commonly used in conjunction with other chemicals. Some of these, such as iodine, are blamed for allergic responses, although testing results in some patients show no signs of allergy to the suspect chemical. Allergies attributed to these other chemicals may possibly be caused by the PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) instead.[22][23] Properties of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) is soluble in water and other polar solvents. For example, it is soluble in various alcohols, such as methanol and ethanol,[24] as well as in more exotic solvents like the deep eutectic solvent formed by choline chloride and urea (Relin).[25] When dry it is a light flaky hygroscopic powder, readily absorbing up to 40% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings. A 2014 study found fluorescent properties of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) and its oxidized hydrolyzate. History of PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) was first synthesized by Walter Reppe and a patent was filed in 1939 for one of the derivatives of acetylene chemistry. PVP/VA W-635 (Polyvinylpyrrolidone Vinyl Acetate) was initially used as a blood plasma substitute and later in a wide variety of applications in medicine, pharmacy, cosmetics and industrial production.

PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate) VP/VA Copolymer. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is a film former. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is produced by the free-radical polymerization of monomers in the ratio of 70/30 (VP/VA). PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat)) copolymer in water. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is a film former produced by the free-radical polymerization on monomers in 70/30 VP/VA ratio. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. PVP/VA W-Series copolymers are linear, random copolymers produced by the free-radical polymerization of the monomers varying from 30/70 to 40/60 vinyl acetate (VA) to vinylpyrrolidone (VP), supplied in water. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat)) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. What is PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) Copolymer? PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. Here at we do not use this ingredient in ANY of our products and especially not in our Hairspray. Our Grapefruit and Lemon Grass Hairspray is not only kind to you but is also kind to the environment by not having an aerosol and instead having an environmentally friendly trigger spray. This beautiful product contains a natural UV protector and hold factor which means no petro-chemicals, plastics or polymers. This gentle formula also means no more eye and scalp irritations. Ashland offers formulators a series of vinylpyrrolidone/vinyl acetate copolymers. Members of the PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymer series serve as primary film formers in a variety of products demanding different degrees of water resistance. These copolymers feature specific affinity for hair, skin and smooth surfaces such as wood, glass, paper, and metal, yet do not require solvents for removal. The advantages of using PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers as film formers are: • film flexibility • good adhesion • water remoistenability • hardness These properties make PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers suitable for a variety of industrial, personal care, and pharmaceutical products. The major industrial applications are in hot melt adhesives, photoresist binders and coatings for inkjet media paper, plastic film and other substrates. • Linear, random copolymers • Increasing vinyl acetate content - increasing hydrophobicity, decreasing hygroscopicity, decreasing Tg • Hydrophilic, transparent, flexible thermoplastic, oxygen permeable films which adhere to glass, plastics and metals • Soluble in alcohols, esters, and ketones, insoluble in ethers and aliphatic hydrocarbons. Soluble in water when VP content greater than 50% • Adhesive and cohesive properties • E = ethanol (EtOH), I = isopropanol, W = water, S = solid The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E and I copolymer Series To fit many application areas, the E and I series of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-635, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) S copolymer PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) S-630 copolymer, a white, odorless powder, is also available at a 60/40 VP/VA weight ratio. It is a high molecular weight, solvent and water soluble copolymer exhibiting a minimum critical solution temperature of approximately 70°C. Films cast from solutions are glossy, translucent and rewettable by water. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W copolymers PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W-735 copolymer is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W-635 copolymer is a 60/40 copolymer also supplied as a 50% aqueous solution. VA (vinyl acetate) is a more hydrophobic molecule than VP (vinylpyrrolidone). Thus increasing VA content of the copolymer causes an increase in hydrophobicity and consequently a decrease in water solubility and hygroscopicity relative to the VP homopolymer. Plasticizers and Polymers: Most PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of Films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E-735 copolymer, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E-535 copolymer and PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E- 335 copolymer. In general, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymer is less hygroscopic than PVP. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are widely used for their excellent film forming properties in the following applications and markets: In hot melt adhesives, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are used in a variety of water remoistenable or water removable adhesives as listed below. Here they offer the formulators performance advantages in film flexibility, adhesiveness and water remoistenability. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are also used in coatings for ink-jet media including paper, plastic films and other substrates to enhance dye receptivity. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) S-630 copolymer is used as a binder to allow the aqueous processing of photoresists. Storage and handling PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat)) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E- and I-series To fit more application areas, the E- and I-series of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-635, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W copolymers PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W-735 is a 70/30 copolymer of PVP and vinyl acetate supplied as a 50% solution in water. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W-635 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E-735, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E-535 and PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E-335. In general, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is less hygroscopic than PVP. Abstract In this study, the influence of copolymer composition on drug-polymer solubility was investigated. The solubility of the model drug celecoxib (CCX) in various polyvinylpyrrolidone/vinyl acetate (PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat)) copolymer compositions (70/30, 60/40, 50/50 and 30/70 w/w) and the pure homopolymers polyvinylpyrrolidone (PVP) and polyvinyl acetate (PVA) was predicted at 25 °C using a thermal analysis method based on the recrystallization of a supersaturated amorphous dispersion (recrystallization method). These solubilities were compared with a prediction based on the solubility of CCX in the liquid monomeric precursors of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat), N-vinylpyrrolidone (NVP) and vinyl acetate (VA), using the Flory-Huggins lattice theory (liquid monomer solubility approach). The solubilities predicted from the liquid monomer solubility approach increased linearly with increasing VP/VA ratio from 0.03-0.60 w/w. Even though the solubilities predicted from the recrystallization method also increased with increasing VP/VA ratio from 0.02-0.40 w/w, the predicted solubility seemed to approach a plateau at high VP/VA ratios. Increasing positive deviations from the Gordon-Taylor equation with increasing VP/VA ratio indicated strong interactions between CCX and the VP repeat unit, which was in accordance with the relatively high solubilities predicted using both methods. As the solubility plateau may be a consequence of steric hindrance caused by the size differences between CCX and the VP repeat units, it is likely that a CCX molecule interacting with a VP repeat unit hinders another CCX molecule from binding to the neighboring repeat units in the polymer chain. Therefore, it is possible that replacing these neighboring hygroscopic VP repeat units with hydrophobic VA repeat units, could increase the physical stability of an amorphous solid dispersion without compromising the drug-polymer solubility. This knowledge could be used advantageously in future development of amorphous drug delivery systems as copolymers could be customized to provide optimal drug-polymer solubility and physical stability. PVP/VA Copolymer. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) acts as a film forming agent. It forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal. It offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) finds application in formulating alcohol-free and hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers. It is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in water. It is produced by the free-radical polymerization of monomers in the ratio of 60/40 (VP/VA). PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) thermoplastic, linear, random vinylpyrrolidone/vinylacetate copolymer. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) used in industrial, specialty and imaging coatings, printing inks and paints. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) provides transparency, flexibility, oxygen permeability and adhesion to glass, plastics and metals. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is produced industrially by vinylation of 2-pyrrolidone, i.e. the base-catalyzed reaction with acetylene.[2] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is the precursor to polyvinylpyrrolidone (PVP), an important synthetic material. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) monomer is commonly used as a reactive diluent in ultraviolet and electron-beam curable polymers applied as inks, coatings or adhesives.[2] Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer made from the monomer N-vinylpyrrolidone.[1] What is PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) Copolymer? PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) Copolymer is the ingredient found in most mainstream hair care products that provides the hold factor. So it is very common in most Hairsprays but also found in gel's, wax's, pomades and styling creams. It is a synthetic ingredient that is derived from petroleum. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) (also known as Polyvinylpyrrolidone) was the main ingredient in the first really successful hairsprays in the early 1950s. This polymer worked as a hairspray because it was soluble in water. This meant it could be rinsed out when you wash your hair. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) tended to absorb water out of the air, giving hair that tacky look that was so common in the sixties. This was fixed with the help of another polymer, a silicone called polydimethylsiloxane. To understand how this silicone made a better hairspray, it helps to understand how the hairspray works in the first place. When you spray it on, the polyvinylpyrrolidone forms a thin coating on the hair. This coating is stiff and keeps the hair from moving around. (See image below) Unfortunately no one was aware of the dangers that came with this Polymer. If particles of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) Copolymer are inhaled, it can cause damage to the lungs in sensitive individuals. It can be considered toxic, since particles may contribute to foreign bodies in the lungs of people. Up until a few years ago, this ingredient was considered safe to use however now it is definitely an ingredient that is better to avoid. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E and I copolymer Series To fit many application areas, the E and I series of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are available as 50% solutions in ethanol and in isopropanol2, respectively. There are four distinct copolymers in the E group: E- 335, E-535, E-735, E-735, and three in the I group: 1-335, 1-535, 1-735. Each differs in monomer ratio and, therefore, in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility, and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios. Storage and handling PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are stable for at least one year under normal conditions of storage but strict precautions should be taken to avoid moisture pickup. The E and I series have flash points in the range of 50-55°F (10-13°C) and are classified as flammable (DOT Flammable) materials. For safety reasons and to prevent moisture pickup due to drum breathing with changes in temperature, store in a dry place below 100°F (38°C) and repack or use in explosion- proof facilities. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) polymers produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals. Polyvinylpyrrolidone/vinyl acetate (PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat)) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are available as white powders or clear solutions in ethanol, isopropanol and water. Polymers in the four ranges of vinylpyrrolidone content (30, 50, 60 and 70 percent), are produced in ethanol or isopropanol. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers with 60 and 70 percent vinylpyrrolidone content are available as solids or as 50 percent aqueous solutions. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E- and I-series To fit more application areas, the E- and I-series of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are available as 50% solutions in ethanol and in isopropanol**, respectively. There are four distinct copolymers in the E group: E-335, E-535, E-735, E-735, and three in the I group: I-335, I-535, I-735. Each differs in monomer ratio, and therefore in properties - water sensitivity, viscosity, softening point, etc. This affords formulators considerable flexibility in creating new products for specific applications. The transparent films formed by all of these copolymers are characterized by adhesion, luster, hardness and water rewettability. Good compatibility with many modifiers and plasticizers permits wide freedom in formulation and broadens the range of hygroscopicity, film flexibility and abrasion resistance. Unmodified copolymers having the lower ratios of vinylpyrrolidone to vinyl acetate exhibit more moisture resistance than products with high ratios of VP to VA. The PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W copolymers PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W-735 is a 70/30 copolymer of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) and vinyl acetate supplied as a 50% solution in water. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) W-735 is a 60/40 copolymer also supplied as a 50% aqueous solution. They are ideal nonionic fixative resins for alcohol-free mousses and gels. They offer formulators outstanding curl and style retention properties without build-up, flaking or dulling of hair. Plasticizers and polymers: Most PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) copolymers are compatible with a variety of nonionic and cationic polymers. Compatibility with anionic copolymers can be achieved through neutralization prior to mixing. Hygroscopicity of films: The inherent water sensitivity of PVP/ VA copolymer films varies with the monomer ratio. Typical data are shown below for PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E-735, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E-535 and PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) E-335. In general, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is less hygroscopic than PVP. Uses Medical PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) was used as a plasma volume expander for trauma victims after the 1950s.It is not preferred as volume expander due to its ability to provoke histamine release and also interfere with blood grouping. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used as a binder in many pharmaceutical tablets;[2] it simply passes through the body when taken orally. (However, autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption.[3] The long-term effects of crospovidone or povidone within the lung are unknown.) PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) added to iodine forms a complex called povidone-iodine that possesses disinfectant properties.[4] This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known under the trade names Pyodine and Betadine, among a plethora of others. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in pleurodesis (fusion of the pleura because of incessant pleural effusions). For this purpose, povidone iodine is equally effective and safe as talc, and may be preferred because of easy availability and low cost.[5] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in some contact lenses and their packaging solutions. It reduces friction, thus acting as a lubricant, or wetting agent, built into the lens. Technical PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as an adhesive in glue stick and hot-melt adhesives PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as a special additive for batteries, ceramics, fiberglass, inks, and inkjet paper, and in the chemical-mechanical planarization process PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as an emulsifier and disintegrant for solution polymerization PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in increase resolution in photoresists for cathode ray tubes (CRT)[9] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in aqueous metal quenching for production of membranes, such as dialysis and water purification filters PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as a binder and complexation agent in agricultural applications such as crop protection, seed treatment and coating PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as a thickening agent in tooth whitening gels[10] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as an aid for increasing the solubility of drugs in liquid and semi-liquid dosage forms (syrups, soft gelatine capsules) and as an inhibitor of recrystallisation PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as an additive to Doro's RNA extraction buffer[citation needed] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as a liquid-phase dispersion enhancing agent in DOSY NMR [11] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as a surfactant, reducing agent, shape controlling agent and dispersant in nanoparticle synthesis and their self-assembly[12] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is used in as a stabilizing agent in all inorganic solar cells[13] Other uses PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers. PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that must be moistened, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions.[14][15] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some. As a food additive, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is a stabilizer and has E number E1201. PVPP (crospovidone) is E1202. It is also used in the wine industry as a fining agent for white wine and some beers. In molecular biology, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at absorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR. In microscopy, PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) is useful for making an aqueous mounting medium.[16] PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) can be used to screen for phenolic properties, as referenced in a 2000 study on the effect of plant extracts on insulin production.[17] Safety of PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) The U.S. Food and Drug Administration (FDA) has approved this chemical for many uses,[18] and it is generally considered safe. However, there have been documented cases of allergic reactions to PVP/povidone, particularly regarding subcutaneous (applied under the skin) use and situations where the PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) has come in contact with autologous serum (internal blood fluids) and mucous membranes. For example, a boy having an anaphylactic response after application of PVP-Iodine for treatment of impetigo was found to be allergic to the PVP/VA W-735 (Polyvinylpyrrolidone Vinyl Acetate, Polivinilpirolidon Vinil Asetat) component of the solution.[19] A woman, who had previ

PYRIDOXINE HCL, N° CAS : 58-56-0 / 12001-77-3 - Pyridoxine hydrochloride. Nom INCI : PYRIDOXINE HCL. Nom chimique : 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride, N° EINECS/ELINCS : 200-386-2 / -. Ses fonctions (INCI). Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Agent d'entretien de la peau : Maintient la peau en bon état

DESCRIPTION:

PVP-VA E-535 acts as a film forming agent.
PVP-VA E-535 is produced by the free-radical polymerization of monomers in the ratio of 50/50 (VP/VA).

PVP-VA E-535 is a 50% solution of linear and random polyvinylpyrrolidone/vinyl acetate (PVP/VA) copolymer in ethanol.


CAS Number:64-17-5
European Community (EC) Number: 607-540-1
Molecular Formula: C10H15NO3
IUPAC Name: ethenyl acetate;1-ethenylpyrrolidin-2-one


SYNONYMS OF PVP-VA E-535:
Copovidone,Kollidon VA64,poly(V-co-V-Ac),poly(vinyl pyrrolidone-co-vinyl acetate),poly(vinylpyrrolidone-co-vinyl-acetate),polyvidone-vinylacetate 64,PVP VA64,PVP-VA,PVPVA 64,25086-89-9,PVP-VA,Polectron 845,Luviskol VA 28I,Luviskol VA 37E,Luviskol VA 64,Kolima 10,Kolima 35,ethenyl acetate;1-ethenylpyrrolidin-2-one,Gantron S 860,Ganex E 535,Copovidone (Technical Grade),GAF-S 630,Luviskol VA 281,Luviskol VA 28 I,Luviskol VA 37 E,I 535,I 635,I 735,S 630,MFCD00134018,Luviskol VA-64,SCHEMBL29127,vinylpyrrolidone/vinyl acetate,Vinyl Pyrrolidone/Vinyl Acetate,N-vinylpyrrolidone/vinyl acetate,1-vinylpyrrolidone vinyl acetate,BCP31918,NSC114023,NSC114024,NSC114025,NSC114026,AKOS015898247,NSC-114023,NSC-114024,NSC-114025,NSC-114026,1-ethenylpyrrolidin-2-one; ethenyl acetate,ethenyl ethanoate; 1-ethenylpyrrolidin-2-one,FT-0659810,50% in ethanol pound copolymer,3:7 pound(c),A817635,acetic acid ethenyl ester; 1-ethenyl-2-pyrrolidinone,733045-73-3

PVP-VA E-535 offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility.
PVP-VA E-535 forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal.
PVP-VA E-535 finds application in formulating hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers.


Series of copolymers covering a range of VP/VA ratios.
PVP/VA S-630 is a white powder while the others are 50% solutions in ethanol (E), isopropanol (I) or water (W).

PVP-VA I-535 by Ashland Specialty Chemical acts as a film forming agent.
PVP-VA E-535 is produced by the free-radical polymerization of monomers in the ratio of 50/50 (VP/VA).
PVP-VA E-535 Shows good propellant compatibility.

PVP-VA E-535 forms transparent, flexible and oxygen permeable films which adhere to glass, plastic and metal.
PVP-VA I-535 finds application in formulating hair care products like hairsprays, colorants, mousses, gels, styling lotions/creams and novelty stylers.
PVP-VA E-535 offers strong & stiff hold, enhanced high humidity curl retention.



CHEMICAL AND PHYSICAL PROPERTIES OF PVP-VA E-535:
Molecular Weight
197.23 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
0
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
3
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
3
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
197.10519334 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
197.10519334 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
46.6Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
14
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
186
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
0
Computed by PubChem
Undefined Atom Stereocenter Count
0
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
2
Computed by PubChem
Compound Is Canonicalized
Yes



SAFETY INFORMATION ABOUT PVP-VA E-535:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.

Pylene glycol is a specific raw material used by manufacturers of green cosmetic products.
Pylene glycol is a synthetic compound in the chemical group called 1,2 glycol.
Pylene glycol is a clear, slightly viscous, colorless, odorless liquid and soluble in water.

CAS Number: 5343-92-0
EC Number: 226-285-3
Molecular Formula (Pylene glycol): C5H12O2
Molecular Weight: 104.15 g/mol

1,2-Pentanediol, Pentane-1,2-diol, 1,2-Dihydroxypentane, 5343-92-0, Pylethylene Glycol, glycol, Glycol, Green Protector, 1,2-Dihydroxypentane, MFCD00010736, 1,a2-aPentanediol, EINECS 226-285-3, BRN 1719151, AI3-03317, NSC 513, 108340-61-0, ACMC-20mbh5, ACMC-1AXDB, EC 226-285-3, 1,2-Pentanediol, 96%, SCHEMBL62155, 3-01-00-02191 (Beilstein Handbook Reference), 1,2-Pentanediol, (2R)-, NSC513, WCVRQHFDJLLWFE-UHFFFAOYSA-, DTXSID10863522, NSC-513, AKOS009156977, AS-40006, SY032914, CS-0017222, FT-0606477, FT-0690841, P1178, 3-(2-NITRO-PHENYL)-ISOXAZOL-5-YLAMINE, 98484-EP2372017A1, A829586, Q3374899

Pylene glycol is a synthetic compound that belongs to the chemical group called 1,2 glycol.
Pylene glycol is a transparent liquid, slightly viscous, colorless, odorless and soluble in water as well as oil.

Pylene glycol is naturally derived from sugar cane.
Pylene glycol is used in many cosmetic products.
Pylene glycol is also referred to by the names 1,2- dihydroxypentane, 1,2-pentanediol, and pentane-1,2-diol.

Pylene glycol is a natural polyhydric alcohol and therefore has the ability to bind water.
This property can be used to moisturize the skin.

Skin is better hydrated, looks significantly brighter and feels better.
At the same time, Pylene glycol naturally helps inhibit the growth of microorganisms on the skin and can therefore be used as an alternative preservative.

Pylene glycol is soluble in water, acts as an extractant and solvent, is biodegradable, can be used in the pH range of 3-10, and is colorless and odorless.
Pylene glycol is made from natural sugar cane bagasse and is therefore ideal for natural cosmetics.

Pylene glycol is a specific raw material used by manufacturers of green cosmetic products.
The most important feature of this preservative is that Pylene glycol is obtained from agricultural products. For example, corn and sugar cane.
Pylene glycol is also commonly called Pentylene glycol.

Pylene glycol is a synthetic compound in the chemical group called 1,2 glycol.
There are two alcohol groups attached to the 1st and 2nd carbon.

Pylene glycol is a clear, slightly viscous, colorless, odorless liquid and soluble in water.
Pylene glycol is also obtained naturally from sugar cane.
Pylene glycol is also fat-soluble and used in many cosmetic products.

Pylene glycol is a natural diol derived from sugar cane bagasse's remaining waste, but a cheap synthetic analog also available in the market.
This multifunctional ingredient is a colorless, odorless, slightly viscous liquid that serves as a moisturizer, solubilizer, preservative, emulsion stabilizer, etc.

Pylene glycol is a well-known moisturizer due to the humectant properties of the molecule, proven scientifically by in-vivo studies.
Also, Pylene glycol is an excellent solubilizer, as Pylene glycol helps to solubilize many challenging ingredients, including fragrances.
Pylene glycol can also increase the clarity of translucent formulations like aqueous gels and toners.

Pylene glycol protects products from harmful bacteria and improves shelf-life, working synergistically with many preservatives, boosting their efficacy and thus helping to reduce their dose.
In addition, Pentane-1,2-diol stabilizes formulations, especially oil-in-water emulsions (as a co-emulsifier with an HLB value of 8.4), which helps reduce the particle size of emulsions, thus providing less coalescence and better stability.

This diol enhances the bioavailability of other ingredients (proven by ex-vivo study), boosting the activity of both lipophilic and hydrophilic actives.
Furthermore, Pylene glycol improves pigment distribution, makes whiter and shinier emulsions, promotes penetration into the skin, and improves the efficiency of cooling agents.

Incorporated in sun care applications, Pylene glycol enhances water resistance and the entire safety of the formula used even in SPF 50+ products.
Pylene glycol also can control the viscosity and texture of the final product.
In skin and hair care products and decorative cosmetics, Pylene glycol concentration can reach up to 5%.

Pylene glycol is used in formulations as an emulsion stabilizer, solvent and a broad spectrum antimicrobial.
Pylene glycol also helps moisturize and has a light, elegant feel to it.

Pylene glycol will leave the skin soft and smooth.
Pylene glycol can help to solubilize and stabilize lipophilic ingredients in aqueous solutions.

Pylene glycol shows a broad spectrum antimicrobial activity against yeasts, moulds, and bacteria.
Pylene glycol disturbs the integrity of microbial cell membranes, a mechanism of action that is unlikely to be affected by resistance.

Being a non-ionic ingredient, the anti-microbial effect of Pylene glycol is largely pH-independent.
Pylene glycol can act as a standalone antimicrobial protection agent.

In addition, Pylene glycol can be easily combined with other classical or non-classical antimicrobial agents, to boost their preservation effects.
Pylene glycol a synthetic, low molecular weight solvent and skin-conditioning agent.

Pylene glycol is commonly used as a skin conditioning agent, due to Pylene glycol (1,2 pentanediol)’s ability to help the skin attract and retain moisture.
As such, Pylene glycol falls into a category of skin care ingredients called humectants.

Pylene glycol is synthetic humectant used in cosmetics and beauty products that is also secondarily used as a solvent and preservative.
Pylene glycol is both water and oil-soluble and Pylene glycol can have moisture-binding and Pylene glycol can have antimicrobial properties.

Pylene glycol also has some anti microbial properties, which can make Pylene glycol a valuable addition to products that are susceptible to contamination of microorganisms.
Pylene glycol is used as a solvent in chemicals produced to soften and smooth the skin in the cosmetic industry.

Pylene glycol is used in sunscreens.
Pylene glycol is a skin moisturizer.

Pylene glycol preserves moisture in the skin, helps to preserve elasticity and moisture of the skin.
Pethylene glycol has an antimicrobial effect.
Pethylene glycol Lipid and dissolved lipophilic actives can be used in penetration enhancing creams and lotions.

Pethylene glycol Hydrogenated phosphotidylcholine is a high viscosity base composed of protected lipids and glycerol.
Pylene glycol is an antimicrobial, chemically produced emulsifier.

Pentilen Glycol has been included in the German Pharmaceutical Codex since 2009.
However, Pylene glycol is not only approved in Germany, but Pylene glycol is also approved as a cosmetic active ingredient worldwide.

Pylene glycol is initially based on the immature juice of sugar beets, while synthetic production is standard.
Pylene glycol is used in day and night creams.

Pylene glycol is a complex system for paraben esters-free cosmetic and personal care products.
Pylene glycol is a multifunctional agent that has excellent efficacy as a biostatic and fungistatic agent.
Pylene glycol can reduce irritation and sensitivity and has a wide broad-spectrum antimicrobial effect.

Pylene glycol is an ingredient which is found naturally in some plants (such as sugar beets and corn cobs) but is most frequently lab-derived when used in cosmetics.
Pylene glycol is a humectant, meaning it binds well to water, making Pylene glycol a good hydrating agent and solvent to aid penetration of other ingredients.
Pylene glycol also helps improve the texture of skin care formulas and has mild preservative properties when used in amounts between 1-5%.

There have been some reports that Pylene glycol (along with other glycols) is a skin sensitizer; however, as with many ingredients, the amount and how it’s used are key.

Pylene glycol is a chemical compound commonly used in the cosmetics and personal care industry as a skincare and beauty product ingredient.
Pylene glycol is also known by its chemical formula C5H12O2.
Pylene glycol is a type of glycol, which is a class of organic compounds that contain multiple hydroxyl (OH) groups.

Pylene glycol proves multifunctional in skincare and cosmetic formulations, offering a spectrum of benefits.
With its hydrating properties, Pylene glycol serves as an effective moisturizer, aiding in maintaining skin moisture levels, particularly beneficial for individuals with dry or dehydrated skin.

Acting as a solvent, Pylene glycol ensures a consistent and uniform texture in products by dissolving other ingredients.
Pylene glycol antimicrobial properties contribute to its role as a preservative, preventing the growth of bacteria and fungi and enhancing Pylene glycol's longevity.

Recognized for Pylene glycol mild and non-irritating nature, Pylene glycol is considered suitable for sensitive skin.
Additionally, Pylene glycol facilitates the penetration of active ingredients, amplifying the efficacy of skincare formulations.
Overall, Pylene glycol is a versatile ingredient, addressing various aspects of skincare, from hydration and preservation to compatibility with different skin types.

Pylene glycol is generally recognized as safe for use in cosmetics and skincare products when used in accordance with regulations and guidelines.
However, as with any ingredient, individual reactions or sensitivities may vary, so it's essential to check Pylene glycol's ingredients list and perform a patch test if you have sensitive skin or allergies.

Uses of Pylene glycol:
Pylene glycol is used as an emulsion stabilizer, humectant, solvent and a broad-spectrum antimicrobial.
Pylene glycol improves texture of the product.

Pylene glycol has all the characteristics of a solvent.
Pylene glycol is not reactive and can dissolve many other compounds.

Pylene glycol is also known to have antimicrobial properties.

Pylene glycol offers a double advantage:
Pylene glycol protects the skin from harmful bacteria, which could otherwise cause body odor and acne problems on the skin.
Secondly, Pylene glycol protects the product from any microbial growth, so Pylene glycol can show the same quality during its use and shelf life.

Skin care:
Due to the two -OH groups, Pylene glycol has a natural tendency to attract water.
Pylene glycol also retains water, which is especially helpful for dry skin.

Pylene glycol is used as a humectant and skin conditioning agent, for Pylene glycol ability to retain moisture.
Pylene glycol is used in moisturizer, baby sunscreen, around-eye cream, antiperspirant/deodorant, serums & essences, hand cream, anti-aging, facial moisturizer/treatment, detanning products, bath oil/salts/soak, body oil, body firming lotion, cuticle treatment, body wash/cleanser, tanning oil, recreational sunscreen

Hair care:
Pylene glycol is used in various hair care products such as hair treatment/serum, hair spray, hair styling aide, shampoo, detangler, beard care, shaving cream, beard oil, conditioner, hair color and bleaching, styling gel/lotion, mask, setting powder/spray

Decorative cosmetics:
Pylene glycol is used in cosmetics such as lipstick, concealer, eye shadow, foundation, CC cream, blush, lip balm, facial powder, bronzer/highlighter, lip gloss, BB cream, makeup primer, brow liner, lip liner, eye liner, lip plumper, lip balm, makeup remover

Uses Area of Pylene glycol:
Pylene glycol is used as a solvent in chemicals produced in the cosmetic industry to soften and smooth the skin.
Pylene glycol has a softening and smoothing effect in this area of use.

Pylene glycol is used together with steroidal hormones in the manufacture of dermatological products.
In these applications, 1,3-butylene glycol and Mono Pentylene glycol are also used as solvents.

This is because 1,3-butylene glycol and Mono Pentylene glycol do not have completely toxic effects.
Pylene glycol is used by combining anti-inflammatory hydrocortisone with Pentylene glycol to relieve minor skin irritation, temporary itching and inflammation.

Pylene glycol is used in the production of allergy medications.
Pylene glycol has antimicrobial properties because Pylene glycol is Dihydric Alcohol.

Pylene glycol helps prevent unwanted microorganisms due to Pylene glycol antimicrobial effect.
Pylene glycol is preferred in the production of quality cosmetic products because Pylene glycol allergic effects are very low.

Pylene glycol is used in the manufacture of daily skin care products due to Pylene glycol moisturizing effect on the skin.
By retaining water on the skin, Pylene glycol makes the skin more vibrant, smooth and plump.

Pylene glycol is used as a solvent in chemicals produced to soften and smooth the skin in the cosmetics industry.
Pylene glycol has a softening and smoothing effect in this area of ​​use.

Pylene glycol is used together with steroidal hormones in the manufacture of dermatological products.
In these applications, Pylene glycol and Mono Pentylene glycol are also used as solvents.

This is because Pylene glycol and Mono Pentylene glycol do not have exactly the toxic effects.
Pylene glycol is used to relieve minor skin irritation, temporary itching and inflammation, by combining the anti-inflammatory hydrocortisone with pylenylene glycol.

Pylene glycol is used in the production of allergy medicines.
Pylene glycol has antimicrobial properties due to being dihydric alcohol.
Due to Pylene glycol antimicrobial effect, Pylene glycol helps to prevent unwanted microorganisms.

Pylene glycol is preferred in the manufacture of quality cosmetic products because of Pylene glycol very low allergic effects.
Pylene glycol is used in the manufacture of daily skin care products due to its moisturizing effect on the skin.
By keeping the water on the skin, Pylene glycol makes the skin more lively, smooth and full.

Applications of Pylene glycol:
Pylene glycol has a wide range of applications.
Intermediate finds applications in Initial product for chemical syntheses, Inks and coatings, Plasticizers and Solvent, Industrial chemicals.

Pylene glycol is used as a plasticizer in cellulose products and adhesives.
Pylene glycol is used as a brake fluid additive.

Pylene glycol reacts with 3,4-dihydro-2H-pyran to get 5-tetrahydropyran-2-yloxy-pentan-1-ol.
Pylene glycol is also used to prepare polyesters for emulsifying agents and resin intermediates.

Pylene glycol is used in ink, toner and colorant products.
In addition to this, Pylene glycol is used in brake fluid compositions.

Pylene glycol is used to produce materials made of polyester or polyurethane, for the manufacturing of monomers, for the manufacture of polyester polyols, polycarbonatedioles and acrylic monomers, for the production of delta valerolactone and for molecules that act as reactive diluents, for the production of halogenated substances and for the production of adhesives, putties and sealing compounds, cleaners and auxiliary agents.
Pylene glycol is used in the processes to produce hydrogen, hydrogen peroxide, sodium perborate and peroxyacetic acid and as an intermediate for pharmaceutical products.
Pylene glycol is used as an ingredient for the production of polymeric thickeners, plasticizers for polyvinyl chloride, sizing agents, surfactants, for starches and chemically modified starch for application in the paper, textile and food industry, for personal hygiene products like shampoo, creams, and for paints.

Benefits of Pylene glycol:
Pylene glycol naturally tends to attract water because Pylene glycol has two -OH groups.
Pylene glycol also retains water, which is especially beneficial for dry skin.

Pylene glycol is used as a humidifier due to its moisture retention capacity.
Pylene glycol has all the properties of a solvent.

Pylene glycol is non-reactive and can dissolve many other compounds.
As mentioned before, due to Pylene glycol ability to naturally retain moisture in the skin, Pylene glycol also nourishes the skin and hair.

Pylene glycol is also known to have antimicrobial properties.
Pylene glycol offers a double advantage – Pylene glycol protects the skin from harmful bacteria that can otherwise cause body odor and acne problems on the skin.

Secondly, Pylene glycol protects the product from microbial growth, so that Pylene glycol can maintain the same quality throughout its use and shelf life.
Pylene glycol is used in the formulations of creams, lotions, moisturizers, cleansers and other skin care products.

Pylene glycol offers several benefits when used in skincare and cosmetic products:

Moisturization:
Pylene glycol helps to hydrate the skin by retaining moisture, making Pylene glycol beneficial for individuals with dry or dehydrated skin.

Solvent:
Pylene glycol serves as a solvent for various cosmetic ingredients, ensuring that the product has a uniform texture and consistency.

Preservation:
Pylene glycol has antimicrobial properties, which help prevent the growth of harmful microorganisms like bacteria and fungi in cosmetic products, extending their shelf life.

Skin-Friendly:
Pylene glycol is known for being mild and non-irritating, making Pylene glycol suitable for sensitive skin types and reducing the risk of skin irritation or allergic reactions.

Enhanced Ingredient Penetration:
Pylene glycol can improve the absorption of other active ingredients into the skin, increasing the effectiveness of skincare formulations.

Peoduction of Pylene glycol:
Pylene glycol is produced synthetically from corn and sugar cane.

Origin of Pylene glycol:
Pylene glycol is based on by-products from manufacturing processes based on sugarcane residues and corn spindles.
However, Pylene glycol is manufactured in the lab as the consumption is relatively high.

Effect of Pylene glycol in the formulation:
antimicrobial
Emulsion stabilization
Moisturizer
Solvent

Physical And Chemical Properties of Pylene glycol:
Pylene glycol is a physically colorless oil-free liquid.
The density of Pylene glycol is 0.994 g/mol.

The melting point of Pylene glycol is -18 °C.
Pylene glycol is a stable chemical.

Pylene glycol should be stored at room temperature.
Pylene glycol is soluble in water.

Safety profile of Pylene glycol:
Pylene glycol does not have any evidence to suggest hazardous to health, toxicity, or carcinogenicity.
Pylene glycol has been found to cause mild irritation to the eyes and skin in skin types that are already sensitized or prone to irritation.

Health Effect of Pylene glycol:
Pylene glycol is a semi-synthetic component.
The starting raw materials are of natural origin, but are transformed into a different form than their original state using various processes under laboratory conditions.
These are raw materials obtained without using animal sources (propolis, honey, beeswax, lanolin, collagen, snail extract, milk, etc.).

Pylene glycol is a criterion that should be taken into consideration for those who want to use vegan products.
Studies have concluded that different effects can be seen on each skin type.

For this reason, the allergy/irritation effect may vary from person to person.
However, Pylene glycol may cause reactions such as stinging, tingling, itching, redness, irritation, skin flaking and swelling, especially in people with sensitive skin types.

Identifiers of Pylene glycol:
CAS Number: 5343-92-0
Chem/IUPAC Name: 2-heptanoyloxypentyl heptanoate
EINECS/ELINCS No: 226-285-3
COSING REF No: 58983

Molecular Formula (Pylene glycol): C5H12O2
Molecular Weight: 104.15 g/mol
Chemical Name: 1,2-Pentanediol
CAS Number: 5343-92-0

Properties of Pylene glycol:
form: solution
mol wt: Mr ~1500
packaging: pkg of 10 × 4 mL
manufacturer/tradename: Roche
shipped in: wet ice
storage temp.: 2-8°C
SMILES string: C(CO)O
InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key: LYCAIKOWRPUZTN-UHFFFAOYSA-N

Other Names of Pylene glycol:

IUPAC Names:
1,5-Pentanediol
1,5-pentanediol
Pentamethylene glycol
pentane,-1,5-diol
Pentane-1,5-diol
pentane-1,5-diol
Pentane-1,5-diol
pentane-1,5-diol
Pentanediol

Pyridine-2,6-dicarboxylic acid (dipicolinic acid) is a chemical compound which plays a role in the heat resistance of bacterial endospores.
Pyridine-2,6-dicarboxylic acid (dipicolinic acid) is also used to prepare dipicolinato ligated lanthanide and transition metal complexes for ion chromatography.
Pyridine-2,6-dicarboxylic acid (dipicolinic acid) is a pyridinedicarboxylic acid carrying two carboxy groups at positions 2 and 6.

CAS: 499-83-2
MF: C7H5NO4
MW: 167.12
EINECS: 207-894-3

Synonyms
Pyridine-2,6-dicarboxylic acid 98%;2,6-Pyridinedicarboxylic acid solution, Eluent concentrate for IC, 0.02M in water;2,6-PyridinedicarboxylicAcid99%;Pyridine-2,6-dicarboxylicacid,98%;IFLAB-BB F0451-0137;LABOTEST-BB LT00848023;RARECHEM AL BO 1335;PYRIDINE;2,6-DICARBOXYLIC ACID;2,6-Pyridinedicarboxylic acid;499-83-2;PYRIDINE-2,6-DICARBOXYLIC ACID;Dipicolinic acid;2,6-Dipicolinic acid;Dipicolinate;2,6-Dicarboxypyridine;2,6-pyridinedicarboxylate;MFCD00006299;UE81S5CQ0G;CHEMBL284104;DTXSID7022043;CHEBI:46837;NSC-176;2,6-Pyridinedicarboxylic acid, 99%;NSC 176;EINECS 207-894-3;UNII-UE81S5CQ0G;2,6-pyridine dicarboxylic acid;pyridine-2;pydcH2;4ih3;pyridine carboxylate, 6d;2,6-pyridinedicarboxylic acid (dipicolinic acid);Oprea1_533632;SCHEMBL34595;2,6-DIPICLINIC ACID;MLS000080748;6-CARBOXYPICOLINIC ACID;DTXCID602043;IFLab1_001781;NSC176;Dipicolinic acid, Beauveria sp.;BDBM26116;2,6-DI-CARBOXY-PYRIDINE;Pyridinedicarboxylic acid-(2,6);HMS1417A21;HMS2231H20;HY-Y1024;Tox21_301129;AC-704;BBL012080;CCG-44216;CL0252;STK092939
;PYRIDINE-2,6-DICARBOXYLICACID;AKOS000112829;AM82010;DB04267;PS-8736;NCGC00071864-02;NCGC00255028-01;CAS-499-83-2;SMR000034075;SY001460;DB-015930;A7431;CS-0016012;EU-0033484;NS00013573;P0554;EN300-18133;Q417164;2,6-Pyridinedicarboxylic acid-2,6-dipicolinic acid;SR-01000600024-2;W-105996;L-042,134;Z57202012;B63A70CE-B9AB-4EA2-834A-6C7634226BB0;F0451-0137;2,6-Pyridinedicarboxylic acid, for ion chromatography, >=99.5% (T);InChI=1/C7H5NO4/c9-6(10)4-2-1-3-5(8-4)7(11)12/h1-3H,(H,9,10)(H,11,12

Pyridine-2,6-dicarboxylic acid (dipicolinic acid) has a role as a bacterial metabolite.
Pyridine-2,6-dicarboxylic acid (dipicolinic acid) is a conjugate acid of a dipicolinate(1-).
Pyridine-2,6-dicarboxylic acid (dipicolinic acid) contains two carboxylic groups on each side of the pyridine ring.
Both groups form rigid 120° angles with the pyridine.
Carboxylic functionality could be complex and bind with metals under certain conditions.
Numerous metal organic frameworks, metal complexes, drugs, and CPs based on PDCA were developed for applications related to gas storage, separation, catalysis, magnetism, and sensing.

Shao et al. researched the solubility of Pyridine-2,6-dicarboxylic acid (dipicolinic acid) in methanol, ethanol, n-propanol, isopropanol, THF, 1,4-dioxane, acetic acid, formic acid, acetonitrile, ethyl acetate, and toluene.
They found that Pyridine-2,6-dicarboxylic acid (dipicolinic acid) solubility was the highest in methanol but the lowest in acetonitrile.
This certified eluent concentrate for ion chromatography is traceable by potentiometric titration to NIST Standard Reference Material.
Pyridine-2,6-dicarboxylic acid (dipicolinic acid) is certified in accordance with ISO Guide 31.
All details about exact content, uncertainty, traceability and expiry date are described in the certificate.

Pyridine-2,6-dicarboxylic acid (dipicolinic acid) Chemical Properties
Melting point: 248-250 °C (dec.)(lit.)
Boiling point: 295.67°C (rough estimate)
Density: 1.5216 (rough estimate)
Vapor pressure: Refractive index: 1.6280 (estimate)
Fp: 188 °C
Storage temp.: Store below +30°C.
Solubility H2O: 1%, clear
pka: 2.16(at 25℃)
Form: Crystalline Powder
Color: White
PH: 2.0 (5g/l, H2O, 20℃)
Water Solubility: 5 g/L (20 ºC)
BRN: 131629
InChIKey: WJJMNDUMQPNECX-UHFFFAOYSA-N
LogP: 0.3 at 25℃ and pH1.8
CAS DataBase Reference: 499-83-2(CAS DataBase Reference)
NIST Chemistry Reference: 2,6-Pyridinedicarboxylic acid(499-83-2)
EPA Substance Registry System: Pyridine-2,6-dicarboxylic acid (dipicolinic acid) (499-83-2)

Uses
Pyridine-2,6-dicarboxylic acid (dipicolinic acid) is used in the preparation of dipicolinato ligated lanthanide and transition metal complexes.
Pyridine-2,6-dicarboxylic acid (dipicolinic acid) acts as a chelating agent for chromium, zinc, manganese, copper, iron and molybdenum.
Pyridine-2,6-dicarboxylic acid (dipicolinic acid)'s calcium-dipcolinic acid complex is used to protect deoxyribonucleic acid (DNA) from heat denaturation which enhances the DNA stability.
Pyridine-2,6-dicarboxylic acid (dipicolinic acid) plays an important role as a marker for the effectiveness of sterilization.

Pyridine-2,6-dicarboxylic acid (dipicolinic acid) is an amphoteric polar metabolite produced by many bacterial and fungal species.
Prior to its discovery as a microbial metabolite, dipicolinic acid had long been recognised as a chelating agent for many metal ions.
Wide distribution of dipicolinic acid among microbes makes Pyridine-2,6-dicarboxylic acid (dipicolinic acid) an important dereplication standard in discovery.
Pyridine-2,6-dicarboxylic acid (dipicolinic acid) reaches high concentrations (~10% w/w) in Bacillus endospores aiding heat resistance and is used in laboratories as a marker for the effectiveness of sterilisation.

Biological role
Dipicolinic acid composes 5% to 15% of the dry weight of Bacillus subtilis spores.
Pyridine-2,6-dicarboxylic acid (dipicolinic acid) has been implicated as responsible for the heat resistance of the endospore, although mutants resistant to heat but lacking dipicolinic acid have been isolated, suggesting other mechanisms contributing to heat resistance are at work.
Two genera of bacterial pathogens are known to produce endospores: the aerobic Bacillus and anaerobic Clostridium.

Pyridine-2,6-dicarboxylic acid (dipicolinic acid) forms a complex with calcium ions within the endospore core.
This complex binds free water molecules, causing dehydration of the spore.
As a result, the heat resistance of macromolecules within the core increases.
The calcium-dipicolinic acid complex also functions to protect DNA from heat denaturation by inserting itself between the nucleobases, thereby increasing the stability of DNA.

Detection
The high concentration of DPA in and specificity to bacterial endospores has long made Pyridine-2,6-dicarboxylic acid (dipicolinic acid) a prime target in analytical methods for the detection and measurement of bacterial endospores.
A particularly important development in this area was the demonstration by Rosen et al. of an assay for Pyridine-2,6-dicarboxylic acid (dipicolinic acid) based on photoluminescence in the presence of terbium, although this phenomenon was first investigated for using DPA in an assay for terbium by Barela and Sherry.

Preparation
Pyridine-2,6-dicarboxylic acid (dipicolinic acid) was synthesized by hydrolyzing of ester prepared by coupling of diethyl 4-hydroxypyridine-2,6-dicarboxylate to bis-halohydrocarbon or bis-halide.

Environmental Behavior
Simple substituted pyridines vary significantly in environmental fate characteristics, such as volatility, adsorption, and biodegradation.
Pyridine-2,6-dicarboxylic acid (dipicolinic acid) is among the least volatile, least adsorbed by soil, and most rapidly degraded of the simple pyridines.
A number of studies have confirmed dipicolinic acid is biodegradable in aerobic and anaerobic environments, which is consistent with the widespread occurrence of the compound in nature.
With a high solubility (5g/liter) and limited sorption (estimated Koc = 1.86), utilization of Pyridine-2,6-dicarboxylic acid (dipicolinic acid) as a growth substrate by microorganisms is not limited by bioavailability in nature.

Pyrithione zinc, also known by its chemical name Pyrithione zinc (ZPT), is an organic compound that contains zinc.
Its chemical formula is C10H8N2O2S2Zn.
Pyrithione zinc is commonly used as an active ingredient in various anti-dandruff shampoos and skincare products due to its antifungal and antibacterial properties.

CAS Number: 13463-41-7
EC Number: 236-671-3

Pyrithione zinc, ZPT, bis(pyridine-2-thionato)zinc, 2-pyridinethiol-1-oxide zinc salt, 1-hydroxy-2(1H)-pyridinethione zinc complex, zinc 2-mercaptopyridine-N-oxide, zinc 2-pyridinethiol 1-oxide, zinc pyridinethione, zinc bis(2-pyridylthio)oxide, zinc pyridinethiolate, zinc dithiopyridine oxide, zinc bis(2-pyridylsulfide)oxide, zinc 1-hydroxy-2-pyridinethione, zinc 2-mercaptopyridine N-oxide, zinc 2-pyridinethione 1-oxide, zinc bis(pyridine-2(1H)-thionato-O,S)Zn, Pyrithione zinc oxide, zinc bis(1-hydroxy-2(1H)-pyridinethione), zinc bis(2-pyridylsulfide)1-oxide, zinc bis(pyridin-2(1H)-thionato)1-oxide, zinc bis(2(1H)-pyridylthio)oxide, zinc 1-hydroxy-2(1H)-pyridinethione, zinc 2-hydroxymercaptopyridine N-oxide, zinc 2-mercaptopyridine-N-oxide complex, zinc 2-pyridinethione oxide, zinc bis(pyridin-2-thionato)1-oxide, zinc bis(pyridin-2-thionato-O,S)oxide, zinc bis(pyridin-2-thionato-S)oxide



APPLICATIONS


Pyrithione zinc is commonly used as an active ingredient in anti-dandruff shampoos.
Pyrithione zinc is applied topically to control and reduce flaking and itching associated with dandruff.
Skincare formulations often include Pyrithione zinc to address seborrheic dermatitis.

Medicated shampoos containing this compound are recommended for treating scalp conditions.
Pyrithione zinc is utilized in various over-the-counter hair care products for its anti-fungal properties.

Pyrithione zinc is an essential component in formulations designed to combat scalp dryness.
Pyrithione zinc is incorporated into skincare products, such as creams and lotions, for treating certain skin disorders.
Pyrithione zinc's antifungal action makes it effective in addressing fungal infections on the skin.

Pyrithione zinc is applied in the development of anti-acne skincare products due to its antimicrobial properties.
Pyrithione zinc plays a role in formulations aimed at alleviating symptoms of psoriasis and eczema.
Pyrithione zinc is found in specialized soaps formulated for individuals with sensitive or problematic skin.

Pyrithione zinc is utilized in foot care products to address fungal infections like athlete's foot.
Pyrithione zinc is included in some sunscreens and sun care products for its antibacterial attributes.
Pyrithione zinc's effectiveness against certain fungi makes it valuable in treating ringworm infections.

Pyrithione zinc is applied in the production of wound care products for its antimicrobial properties.
Hair conditioners and treatments may contain this compound to promote a healthier scalp.
Pyrithione zinc is explored for its potential in formulations targeting acne-related skin concerns.

Pyrithione zinc is utilized in personal care products for both its therapeutic and cosmetic benefits.
Pyrithione zinc is employed in the manufacturing of anti-itch creams and lotions.
Pyrithione zinc is used in skincare regimens to maintain a balanced and healthy skin microbiome.

Pyrithione zinc finds application in veterinary products for addressing fungal infections in animals.
Pyrithione zinc's broad-spectrum antimicrobial activity contributes to its versatility in formulations.
Pyrithione zinc is an active ingredient in some face cleansers and exfoliating products.

Pyrithione zinc is applied in the development of specialized products for individuals with sensitive scalps.
Pyrithione zinc is featured in various cosmetic and therapeutic formulations, showcasing its widespread applications.

Pyrithione zinc is often found in formulations for baby shampoos, providing a gentle solution for delicate scalps.
Pyrithione zinc is utilized in hair tonics and serums to promote a healthy scalp environment.
Some facial cleansers incorporate Pyrithione zinc to address skin conditions such as rosacea.

Scalp masks containing this compound are used for deep conditioning and dandruff control.
Pyrithione zinc is applied in leave-in hair products for continuous scalp care.
Pyrithione zinc is featured in anti-aging creams for its potential in maintaining skin health.

Pyrithione zinc is included in deodorants for its antimicrobial properties that help control odor.
Pyrithione zinc is used in formulations for body washes targeting fungal and bacterial skin infections.

Pyrithione zinc is employed in the textile industry to impart antimicrobial properties to fabrics.
Some laundry detergents utilize this compound to enhance their antibacterial capabilities.
Pyrithione zinc is incorporated into hand sanitizers and antibacterial hand soaps for added efficacy.

Pyrithione zinc is explored for its potential in wound dressings to prevent infections.
Pyrithione zinc is featured in foot powders and sprays to combat fungal growth and foot odor.
Pyrithione zinc is applied in the development of anti-aging skincare products for its skin-regenerating properties.

Pyrithione zinc is utilized in hair color protection products to maintain scalp health.
Pyrithione zinc finds application in pet shampoos for addressing skin conditions in animals.
Pyrithione zinc is used in the manufacturing of textiles to prevent microbial growth and odors.

Pyrithione zinc is explored for its potential use in oral care products for its antibacterial effects.
Pyrithione zinc is incorporated into wound healing ointments to prevent bacterial contamination.

Pyrithione zinc is utilized in the production of facial masks for its purifying properties.
Pyrithione zinc is applied in the development of acne spot treatments for targeted skincare.
Some antiperspirants feature Pyrithione zinc to enhance their antibacterial properties.
Pyrithione zinc is used in hair styling products to promote scalp health while styling hair.

Pyrithione zinc is incorporated into intimate hygiene products for its antimicrobial benefits.
Pyrithione zinc is featured in cosmetic formulations to address skin redness and irritation.

Pyrithione zinc is commonly added to facial moisturizers to provide both hydration and antibacterial benefits.
Pyrithione zinc finds use in exfoliating scrubs, contributing to a comprehensive skincare routine.
Some nail care products contain Pyrithione zinc to address fungal infections around the nails.

Pyrithione zinc is utilized in the formulation of anti-itch creams and lotions for various skin irritations.
Pyrithione zinc is incorporated into makeup remover solutions for its skin-conditioning properties.
Pyrithione zinc is applied in the production of scalp masks to nourish and soothe the skin.

Pyrithione zinc is found in pre-shave products to help prevent irritation and ingrown hairs.
Pyrithione zinc is used in the manufacturing of acne cleansers for its antimicrobial action.
Pyrithione zinc is added to intimate washes to maintain a balanced microbial environment.

Pyrithione zinc is utilized in barrier creams to protect the skin from external irritants.
Pyrithione zinc is employed in foot creams for its antifungal effects on cracked heels.
Pyrithione zinc is featured in anti-chafing products to prevent skin irritation during physical activities.

Pyrithione zinc is explored for potential use in scalp serums promoting hair growth.
Pyrithione zinc is applied in the development of antifungal powders for various skin regions.
The compound is used in bath additives to address skin conditions such as eczema.
Pyrithione zinc is included in antifungal ointments for treating skin infections.

Pyrithione zinc is found in wound care sprays, aiding in the prevention of infections in minor cuts and abrasions.
Pyrithione zinc is applied in the formulation of dermatologically tested sunscreens.
Pyrithione zinc is used in antiperspirant creams for its bacteria-controlling properties.

Pyrithione zinc is explored for its potential in eye creams to address concerns like redness and puffiness.
Pyrithione zinc is utilized in acne patches for targeted treatment of blemishes.
Pyrithione zinc is featured in aftershave products to soothe and protect the skin.
Pyrithione zinc is applied in the production of lip balms to address chapped or irritated lips.

The compound is found in anti-cellulite creams for its skin-toning effects.
Pyrithione zinc is included in hair growth formulations for its potential scalp health benefits.



DESCRIPTION


Pyrithione zinc, also known by its chemical name Pyrithione zinc (ZPT), is an organic compound that contains zinc.
Its chemical formula is C10H8N2O2S2Zn.
Pyrithione zinc is commonly used as an active ingredient in various anti-dandruff shampoos and skincare products due to its antifungal and antibacterial properties.

Pyrithione zinc is effective in controlling the growth of yeast-like fungi, including Malassezia, which is associated with dandruff and seborrheic dermatitis.
Pyrithione zinc works by inhibiting the growth of these microorganisms, helping to alleviate symptoms such as flaking and itching of the scalp.

Pyrithione zinc is an organometallic complex containing zinc and sulfur.
Pyrithione zinc exhibits potent antifungal properties.
Known for its role in anti-dandruff formulations, Pyrithione zinc helps control scalp conditions.
Pyrithione zinc is effective against the growth of yeast-like fungi, particularly Malassezia.

Pyrithione zinc is commonly used in shampoos designed to treat seborrheic dermatitis.
Pyrithione zinc inhibits the reproduction of microorganisms associated with skin flaking and itching.
With its antibacterial attributes, Pyrithione zinc contributes to maintaining a healthy scalp.

Pyrithione zinc is often found in skincare products aimed at treating various dermatological conditions.
Pyrithione zinc has a complex molecular structure, involving pyridine and thiol groups.

Pyrithione zinc is synthesized to create a stable and effective solution for topical applications.
Its unique formulation makes it suitable for incorporation into a variety of personal care products.
The efficacy of Pyrithione zinc lies in its ability to disrupt the cell membranes of fungi.

Pyrithione zinc acts as a preventative measure against the recurrence of dandruff and related issues.
Pyrithione zinc has been extensively studied for its safety and efficacy in skincare formulations.

Pyrithione zinc is a key ingredient in medicated shampoos recommended by dermatologists.
Pyrithione zinc's mechanism of action involves targeting specific enzymes critical for fungal growth.
Pyrithione zinc is widely recognized for its role in improving the overall health of the scalp.

As an active ingredient, it is included in various over-the-counter and prescription products.
Pyrithione zinc is known to provide relief from itching and redness associated with certain skin conditions.
Pyrithione zinc is a versatile compound used in both cosmetic and therapeutic applications.

Pyrithione zinc has been employed in the development of formulations for treating psoriasis and eczema.
Pyrithione zinc's antifungal properties make it a valuable addition to anti-acne skincare products.
Pyrithione zinc is often recommended by healthcare professionals for its efficacy in addressing skin issues.

Pyrithione zinc's ability to regulate skin flora contributes to its widespread use in skincare.
With its well-established safety profile, Pyrithione zinc remains a trusted ingredient in personal care formulations.



PROPERTIES


Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)[1]
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)



FIRST AID


Inhalation:

Move the affected person to fresh air if they have inhaled the compound.
If breathing difficulties persist, seek immediate medical attention.
Provide artificial respiration if the person is not breathing.


Skin Contact:

Remove contaminated clothing and rinse the affected skin with plenty of water.
Wash the skin thoroughly with mild soap and water.
If irritation or redness persists, seek medical attention.
If there is prolonged or massive skin contact, use appropriate protective measures to avoid further exposure.


Eye Contact:

Rinse eyes gently with water for at least 15 minutes, holding the eyelids open.
Seek medical attention if irritation, redness, or other symptoms persist.
Remove contact lenses if easily removable after rinsing.


Ingestion:

If the compound is ingested, do not induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth with water and drink plenty of water.
Seek immediate medical attention.
Provide medical personnel with information on the ingested substance.


General Advice:

Keep the affected person calm.
If medical attention is needed, provide relevant information on the compound, including its name (Pyrithione zinc) and, if possible, the concentration.
In case of exposure to high concentrations or unusual symptoms, contact a poison control center or seek medical advice promptly.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate protective clothing, including gloves and safety goggles or a face shield.
Use protective equipment as specified in the product's safety data sheet (SDS) or other safety documentation.

Ventilation:
Use the compound in a well-ventilated area to minimize inhalation exposure.
If handling in an enclosed space, ensure adequate local exhaust ventilation.

Avoid Contact:
Avoid direct skin and eye contact with the undiluted substance.
In case of contact, promptly wash the affected area with water.

Handling Procedures:
Follow good industrial hygiene practices.
Do not eat, drink, or smoke while handling the substance.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
In the event of a spill, contain the material and absorb with an inert material (e.g., sand or vermiculite).
Collect the spilled material in an appropriate container for disposal.


Storage:

Storage Conditions:
Store Pyrithione zinc in a cool, dry, and well-ventilated area.
Keep containers tightly closed when not in use to prevent contamination and moisture absorption.

Temperature Control:
Avoid exposure to extreme temperatures. Store at temperatures recommended by the manufacturer.

Compatibility:
Store away from incompatible materials and substances.
Follow the manufacturer's recommendations regarding compatibility with other chemicals.

Container Material:
Use containers made of materials compatible with Pyrithione zinc.
Check for container integrity regularly to prevent leaks or spills.

Handling of Containers:
Handle containers with care to prevent damage.
Do not drag or slide containers, as this may cause damage and compromise integrity.

Labeling:
Ensure proper labeling of containers with product names, hazard information, and handling instructions.
Clearly mark storage areas with appropriate signage.

Segregation:
Segregate Pyrithione zinc from incompatible substances and materials.
Follow regulations and guidelines for the storage of chemicals in your location.

Fire Precautions:
Keep away from ignition sources and open flames.
Follow fire safety regulations in the storage area.

Emergency Response Information:
Keep emergency response information, such as contact numbers for emergency services and relevant healthcare professionals, readily available.

Plasdone’, PVP, Polyvidone, Povidone CAS # : 9003-39-8

DISODIUM PYROPHOSPHATE, N° CAS : 7758-16-9 - Pyrophosphate disodique. Origine(s) : Synthétique. Nom INCI : DISODIUM PYROPHOSPHATE. N° EINECS/ELINCS : 231-835-0. Le pyrophosphate disodique se présente sous la forme d'une poudre cristalline blanche. Dans les cosmétiques, on s'en sert d'agent tampon, de chélateur et d'anti-corrosif. Ses fonctions (INCI): Anticorrosif : Empêche la corrosion de l'emballage Régulateur de pH : Stabilise le pH des cosmétiques Agent de chélation : Réagit et forme des complexes avec des ions métalliques qui pourraient affecter la stabilité et / ou l'apparence des produits cosmétiques

219-574-0 [EINECS]; 2466-09-3 [RN]; Acide diphosphorique [French] [ACD/IUPAC Name]; Diphosphoric acid ; Diphosphorsäure [German] [ACD/IUPAC Name]; hydrogen pyrophosphate; MFCD00011343 [MDL number]; phosphoric anhydride; Pyrophosphic acid; Pyrophosphoric Acid; (phosphonooxy)phosphonic acid [2466-09-3] 03.09.2466 1314-56-3 [RN] 14000-31-8 [RN] 2-(5-Chloro-2-methoxyphenyl)pyrrolidine [ACD/IUPAC Name] 2',3'-Dideoxycytidine 5'-triphosphate 215-236-1 [EINECS] 2'-Deoxyadenosine 5'-triphosphate 33943-49-6 [RN] 3-methylbut-3-enyl trihydrogen diphosphate 69639-93-6 [RN] 7722-88-5 [RN] ADENOSINE-5'-DIPHOSPHATE Adenosine-5'-triphosphate ADP ATP CTP CYTIDINE-5'-TRIPHOSPHATE dCt dimethylallyl diphosphate Diphosphorsaeure DMA DPO DTP IPE MFCD02663458 [MDL number] Oxy-1,1-diphosphonic acid phosphono dihydrogen phosphate Phosphonooxyphosphonic acid Phosphoricanhydride Phosphotex POP PPV Pyrophosphoricacid Pyrophosphorsaeure THYMIDINE-5'-TRIPHOSPHATE TTP μ-oxido-bis(dihydroxidooxidophosphorus) 焦磷酸 [Chinese]

PYRUVIC ACID, N° CAS : 127-17-3, Nom INCI : PYRUVIC ACID, Nom chimique : Propanoic Acid, 2-oxo, N° EINECS/ELINCS : 204-824-3. Ses fonctions (INCI). Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit

pyrus communis flower extract; extract of the flowers of the pear, pyrus communis l., rosaceae; european pear flower extract CAS NO:90082-43-2

Quartemine; 1-Hexadecanaminium, N,N,N-trimethyl-, chloride cas no: 112-02-7

Yumuşatıcı (%6-10)

Quartemine; 1-Hexadecanaminium, N,N,N-trimethyl-, chloride cas no: 112-02-7

QUARTZ, N° CAS : 14808-60-7 - E551, Nom INCI : QUARTZ, N° EINECS/ELINCS : 238-878-4. Ses fonctions (INCI). Agent Abrasif : Enlève les matières présentes en surface du corps, aide à nettoyer les dents et améliore la brillance.

Didecyl Dimethyl Ammonium Carbonate; Didecyl Dimethyl Ammonium Bicarbonate; Carboquat™ H;

Coco-ethyldimonium ethosulfate; Quaternary ammonium compounds, coco alkyl ethyldimethyl, ethyl sulfates; Cocodimethylammonium diethyl sulfate;Cocodimethylethylammonium ethosulfate; Cocodimethylethylammonium, ethylsulfate; Dimethylcocoethylammonium, ethylsulfate; Ethyldimethylcocoammonium, ethyl sulfate; N,N-Dimethyl-N-ethyl-N-cocoammonium ethylsulfate CAS NO:68308-64-5

alkyl ethyl benzyl dimethyl ammonium chloride; Dodecyl(ethylbenzyl)dimethylammonium chloride; QUATERNIUM-14, N° CAS : 27479-28-3. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-14. Nom chimique : Dodecyl(ethylbenzyl)dimethylammonium chloride. N° EINECS/ELINCS : 248-486-5, Classification : Ammonium quaternaire. Ses fonctions (INCI). Antimicrobien : Aide à ralentir la croissance de micro-organismes sur la peau et s'oppose au développement des microbes; Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface; Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance; Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation. Noms français : AMMONIUM, DODECYL(AR-ETHYLBENZYL)DIMETHYL-, CHLORIDE; BENZENEMETHANAMINIUM, N-DODECYL-AR-ETHYL-N,N-DIMETHYL-, CHLORIDE; Chlorure de dodécyldiméthyl(éthylbenzyl)ammonium. Noms anglais : Dodecyldimethyl(ethylbenzyl)ammonium chloride. TETRADECYLDIMETHYL(ETHYLBENZYL)AMMONIUM CHLORIDE; alkyl ethyl benzyl dimethyl ammonium chloride; benzenemethanaminium, N-dodecyl-ar-ethyl-N,N-dimethyl-, chloride; dodecyl (ethyl benzyl) dimethyl ammonium chloride; dodecyl dimethyl ethyl benzyl ammonium chloride; dodecyl dimethyl ethylbenzyl ammonium chloride; dodecyl-[(4-ethylphenyl)methyl]-dimethylazanium chloride; N- dodecyl-ar-ethyl-N,N-dimethylbenzenemethanaminium chloride; dodecyldimethyl(ethylbenzyl)ammonium chloride; quaternary ammonium compounds, C12-14-alkyl[(ethylphenyl)methyl]dimethyl, chloridesUtilisation et sources d'émission: Additif alimentaire, fabrication de cosmétiques. 273-318-2 [EINECS] 68956-79-6 [RN] Benzenemethanaminium, 4-ethyl-N,N-dimethyl-N-tetradecyl-, chloride (1:1) [ACD/Index Name] Chlorure de N-(4-éthylbenzyl)-N,N-diméthyl-1-tétradécanaminium [French] [ACD/IUPAC Name] DIMETHYL ETHYLBENZYL MYRISTYL AMMONIUM CHLORIDE N-(4-Ethylbenzyl)-N,N-dimethyl-1-tetradecanaminium chloride [ACD/IUPAC Name] N-(4-Ethylbenzyl)-N,N-dimethyl-1-tetradecanaminiumchlorid [German] [ACD/IUPAC Name] (4-ethylbenzyl)-dimethyl-myristyl-ammonium chloride (4-ethylbenzyl)-lauryl-dimethyl-ammonium chloride (4-ethylphenyl)methyl-dimethyl-tetradecylammonium chloride (4-ethylphenyl)methyl-dimethyl-tetradecyl-ammonium chloride (4-ethylphenyl)methyl-dimethyl-tetradecylazanium chloride (4-ethylphenyl)methyl-dimethyl-tetradecyl-azanium chloride [(4-ETHYLPHENYL)METHYL]DIMETHYLTETRADECYLAZANIUM CHLORIDE 27479-28-3 [RN] Benzenemethanaminium, N-dodecyl-ar-ethyl-N,N-dimethyl-, chloride Dodecyl dimethyl ethylbenzyl ammonium chloride dodecyl(ethylbenzyl)dimethylammonium chloride dodecyl-[(4-ethylphenyl)methyl]-dimethylammonium chloride dodecyl-[(4-ethylphenyl)methyl]-dimethyl-ammonium chloride dodecyl-[(4-ethylphenyl)methyl]-dimethylazanium chloride dodecyl-[(4-ethylphenyl)methyl]-dimethyl-azanium chloride DODECYLDIMETHYL(ETHYLBENZYL)AMMONIUM CHLORIDE EINECS 248-486-5 N-[(4-Ethylphenyl)methyl]-N,N-dimethyltetradecan-1-aminium chloride N-ALKYL ETHYLBENZYL DIMETHYL AMMONIUM CHLORIDE (C12-C14) N-Dodecyl-ar-ethyl-N,N-dimethylbenzenemethanaminium chloride NOCAS_872364 Quaternary ammonium compounds, C12-18-alkyl[(ethylphenyl)methyl]dimethyl, chlorides QUATERNIUM-14 TETRADECYLDIMETHYL(ETHYLBENZYL)AMMONIUM CHLORIDE alkyl ethyl benzyl dimethyl ammonium chloride benzenemethanaminium, N-dodecyl-ar-ethyl-N,N-dimethyl-, chloride dodecyl (ethyl benzyl) dimethyl ammonium chloride dodecyl dimethyl ethyl benzyl ammonium chloride dodecyl dimethyl ethylbenzyl ammonium chloride dodecyl-[(4-ethylphenyl)methyl]-dimethylazanium chloride N- dodecyl-ar-ethyl-N,N-dimethylbenzenemethanaminium chloride dodecyldimethyl(ethylbenzyl)ammonium chloride quaternary ammonium compounds, C12-14-alkyl[(ethylphenyl)methyl]dimethyl, chlorides

QUATERNIUM-15, N° CAS : 4080-31-3 / 51229-78-8. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-15, Nom chimique : Methenamine 3-chloroallylochloride, N° EINECS/ELINCS : 223-805-0 / 426-020-3. Classification : Ammonium quaternaire, Règlementé, Libérateur de Formaldéhyde, Conservateur. Restriction en Europe : La concentration maximale autorisée dans les préparations cosmétiques prêtes à l'emploi est de 0,2 %. Interdit en Europe à partir du 12 juin 2019. Ses fonctions (INCI): Conservateur : Inhibe le développement des micro-organismes dans les produits cosmétiques.Quaternium-15 (systematic name: hexamethylenetetramine chloroallyl chloride) is a quaternary ammonium salt used as a surfactant and preservative in many cosmetics and industrial substances. It acts as an antimicrobial agent because it acts as a formaldehyde releaser,[2][3] though doing so can also cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin. Noms français : 1-(3-CHLORO-2-PROPENYL)-3,5,7-TRIAZA-1-AZONIATRICYCLO(3.3.1.1(3,7))DECANE CHLORIDE 1-(3-CHLOROALLYL)-3,5,7-TRIAZA-1-AZONIAADAMANTANE CHLORIDE 3,5,7-TRIAZA-1-AZONIAADAMANTANE, 1-(3-CHLOROALLYL)-, CHLORIDE 3,5,7-TRIAZA-1-AZONIATRICYCLO(3.3.1.1(3,7)DECANE, 1-(3-CHLORO-2-PROPENYL)-, CHLORIDE 3,5,7-TRIAZA-1-AZONIATRICYCLO(3.3.1.13,7)DECANE, 1-(3-CHLORO-2-PROPENYL)-, CHLORIDE 3-Chloroallylochlorure de méthenamine CCTA Chlorure de 1-(3-chloroallyl)-3,5,7-triaza-1-azonia-adamantane Chlorure de N-(chloro-3 allyl) hexaminium Chlorure de N-(chloro-3 allyl) hexaminium (Quaternium 15) N-(3-CHLOROALLYL)HEXAMINIUM CHLORIDE N-(CHLORO-3 ALLYL) HEXAMINIUM, CHLORURE DE Noms anglais :Methenamine 3-chloroallylochloride; Utilisation et sources d'émission : Bactéricide, fabrication de cosmétiques. 1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride 3,5,7-Triaza-1-azoniaadamantane, 1-(3-chloroallyl)-, chloride 3,5,7-Triaza-1-azoniatricyclo(3.3.1.13,7)decane, 1-(3-chloro-2-propen-1-yl)-, chloride (1:1) 3,5,7-Triaza-1-azoniatricyclo(3.3.1.13,7)decane, 1-(3-chloro-2-propenyl)-, chloride Cinartc 200 Dowco 184 Dowicide Q Dowicil 100 Dowicil 75 Hexamethylenetetramine chloroallyl chloride Methenamine 3-chloroallylochloride N-(3-Chloroallyl)hexaminium chloride Quaternium-15 XD-1840 Translated names 1-(3-chlorallyl)-3,5,7-triaza-1-azoniaadamantan-chlorid (CTAC) (cs) 3-chloroallylochlorure de méthénamine (CTAC) (fr) 3-Cloroalilcloreto de metenamina (CTAC) (pt) 3-Cloroalilocloruro de metenamina (CTAC) (es) 3-cloroallilocloruro di metenamina (CTAC) (it) 3-Kloroalliloklorur tal-metenammina (CTAC) (mt) 3-χλωραλλυλοχλωρίδιο της μεθεναμίνης (CTAC) (el) Chlorek 3-chloroallilometenaminy (CTAC) (pl) Meteenamiin-3-kloroallülokloriid (CTAC) (et) Metenamiini-3-klooriallyylokloridi (CTAC) (fi) Metenamin 3-cloroaliloclorură (CTAC) (ro) Metenamin 3-kloroaliloklorid (CTAC) (hr) Metenamin-3-kloroallylklorid (CTAC) (sv) Metenamino 3-chloralilochloridas (CTAC) (lt) Methenamin-3-chlorallylchlorid (CTAC) (de) methenamin-3-chlorallylochlorid (CTAC) (da) Methenamine 3-chloroallylochloride (CTAC) (no) Methenamine-3-chloorallylchloride (CTAC) (nl) Metén-amin-3-klór-allil-klorid (CTAC) (hu) meténamín-3-chlóralylchlorid (CTAC) (sk) Metēnamīna 3-hloralilhlorīds (CTAC) (lv) Метенаминов 3-хлороалилохлорид (CTAC) (bg) 1-(3-chloroprop-2-en-1-yl)-3,5,7-triaza-1-azoniatricyclo[3.3.1.1~3,7~]decane chloride 3,5,7-Triaza-1-azoniatricyclo[3.3.1.13,7]decane,1-(3-chloro-2-propenyl)-, chloride 3,5,7-Triaza-1-azoniatricyclo[3.3.1.13,7]decane,1-(3-chloro-2-propenyl)-, chloride (9CI) 3,5,7-TRIAZA-1-AZONIATRICYCLODECANE-1-(3-CHLORO-2-PROPENYL)-,CHLORIDE CHLOROALLYLTRIAZAAZONIAADAMANTANE CHLORIDE. 1-(3-Chloro-2-propenyl)-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane Chloride 1-[(2E)-3-Chlor-2-propen-1-yl]-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decanchlorid [German] [ACD/IUPAC Name] 1-[(2E)-3-Chloro-2-propen-1-yl]-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane chloride [ACD/IUPAC Name] 1-[(2E)-3-Chloroprop-2-en-1-yl]-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane chloride 1-[(2E)-3-chloroprop-2-en-1-yl]-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane chloride 2W5B4VJ152 3,5,7-Triaza-1-azoniaadamantane, 1- (3-chloroallyl)-, chloride 3,5,7-Triaza-1-azoniatricyclo[3.3.1.13,7]decane, 1-[(2E)-3-chloro-2-propen-1-yl]-, chloride (1:1) [ACD/Index Name] 3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane, 1-[(2E)-3-chloro-2-propenyl]-, chloride 3,5,7-Triaza-1-azoniatricyclo[3.3.1.13,7]decane, 1-(3-chloro-2-propenyl)-, chloride 4080-31-3 [RN] Chlorure de 1-[(2E)-3-chloro-2-propén-1-yl]-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]décane [French] [ACD/IUPAC Name] Quaternium-15 [Wiki] QUATERNIUM-15 TRANS-FORM 1-(3-Chloroallyl)-1,3,5,7-tetraazaadamantan-1-ium chloride 1-(3-CHLOROALLYL)-3,5,7-TRIAZA-1-AZONIAADAMANTANECHLORIDE 1-(3-Chloroallyl)-3,5,7-triazo-1-azoniaadamantane chloride 3,5,7-Triaza-1-azoniaadamantane, 1-(3-chloroallyl)-, chloride 3,5,7-Triaza-1-azoniatricyclo(3.3.1.13,7)decane, 1-(3-chloro-2-propenyl)-, chloride 51229-78-8 [RN] Chloroallyl methenamine chloride Cinartc 200 DOWICIDE Q Dowicil 100 Dowicil 100[1-(3-chloroallyl)-3,5,7-triazo-1-azoniaadamantane chloride] Dowicil 200 Dowicil 75 Dowicil75 EINECS 223-805-0 Hexamethylenetetramine chloroallyl chloride Methenamine 3-chloroallylochloride N-(3-CHLORALLYL)HEXAMINIUM CHLORIDE N-(3-Chloroallyl)hexaminium chloride quaternium 15

QUATERNIUM-16, N° CAS : 64425-88-3 / 35239-12-4, Origine(s) : Synthétique, Nom INCI : QUATERNIUM-16, N° EINECS/ELINCS : 264-890-4 / -. Classification : Ammonium quaternaire: Ses fonctions (INCI). Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Quaternary ammonium compounds, tris(hydroxyethyl)tallow alkyl, chlorides; 1-Octadecanaminium, N,N,N-tris(2-hydroxyethyl)-, chloride (1:1) [ACD/Index Name] 35239-12-4 [RN] Chlorure de N,N,N-tris(2-hydroxyéthyl)-1-octadécanaminium [French] [ACD/IUPAC Name] N,N,N-Tris(2-hydroxyethyl)-1-octadecanaminium chloride [ACD/IUPAC Name] N,N,N-Tris(2-hydroxyethyl)-1-octadecanaminiumchlorid [German] [ACD/IUPAC Name] QUATERNIUM-16 TRIS(2-HYDROXYETHYL)(OCTADECYL)AZANIUM CHLORIDE

Quaternium-15 is also known by other names, such as Dowicil 100, Methenamine 3-chloroallylochloride, and several others listed in the previous response.
Quaternium-15 is commonly used in personal care products such as cosmetics, soaps, and shampoos.
Quaternium-15 releases small amounts of formaldehyde, which can cause skin irritation and allergic reactions in some individuals.

CAS Number: 51229-78-8
Molecular Formula: C9H16Cl2N4
Molecular Weight: 251.16

Synonyms: Quaternium-15, Quaternium-15 trans-form, 4080-31-3, Quaternim-15 trans-form, Methenamine 3-chloroallylochloride, Dowicil 100, UNII-2W5B4VJ152, 194805-30-6, Hexamethylenetetramine chloroallyl chloride, Dowicide Q, Quaternium 15, 2W5B4VJ152, Dowicil 75, Cinartc 200, 1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride, N-(3-Chloroallyl)hexaminium chloride, Dowco 184, XD-1840, 3,5,7-Triaza-1-azoniatricyclo[3.3.1.13,7]decane, 1-(3-chloro-2-propenyl)-, chloride, Caswell No. 181, CHEBI:59607, UNII-E40U03LEM0, CCRIS 1398, HSDB 6820, 3,5,7-Triaza-1-azoniatricyclo(3.3.1.13,7)decane, 1-(3-chloro-2-propenyl)-, chloride, 1-[(2E)-3-chloroprop-2-en-1-yl]-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane chloride, EINECS 223-805-0, EPA Pesticide Chemical Code 017901, NSC 172971, E40U03LEM0, 1-(3-chloro-2-propenyl)-3,5,7-triaza-1-azoniatricyclo(3.3.1.13,7)decane chloride, 3,5,7-Triaza-1-azoniaadamantane, 1-(3-chloroallyl)-, chloride, AKOS016009992, n-(3-chloroallyl) hexaminium chloride, LS-13676, EN300-18430961, 3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane, Q27255687, (E)-1-(3-Chloroallyl)-1,3,5,7-tetraazaadamantan-1-ium chloride, 1-(3-chloroprop-2-en-1-yl)-1,3,5,7-tetraazatricyclo[3.3.1.1,3,7]decan-1-ium chloride, 1-[3-chloroprop-2-en-1-yl]-3,5,7-triaza-1-azoniatricyclo[3.3.1.1(3),(7)]decanium chloride, 3,5,7-TRIAZA-1-AZONIATRICYCLO(3.3.1.13,7)DECANE, 1-((2E)-3-CHLORO-2-PROPEN-1-YL)-, CHLORIDE (1:1), 3,5,7-Triaza-1-azoniatricyclo(3.3.1.13,7)decane, 1-(3-chloro-2-propen-1-yl)-, chloride (1:1)

Quaternium-15 has been banned in the EU since 2017 and a bill was introduced in the US in 2017 to require the FDA to investigate its safety.
Its use is regulated in many countries due to its potential health effects, and there are restrictions on the maximum allowable concentration in cosmetic products.
Quaternium-15 commonly found in shampoos, conditioners, lotions, creams, and makeup products.

Quaternium-15 is an allergen, and can cause dermatitis.
Many of those with an allergy to quaternium-15 are also allergic to formaldehyde.
At low pHs, Quaternium-15 would be expected to release significant amounts of formaldehyde due to acid hydrolysis via the Delepine reaction.

Allergic sensitivity to quaternium-15 can be detected using a patch test.
Quaternium-15 is the single most often found cause of allergic contact dermatitis of the hands (16.5% in 959 cases).
In 2005–06, Quaternium-15 was the fourth-most-prevalent allergen in patch tests (10.3%).

Although quaternium-15 releases low amounts of formaldehyde.
Even so, Johnson & Johnson announced plans to phase out its use of quaternium-15 in cosmetic products by 2015 in response to consumer pressure.
Quaternium-15, a known skin toxicant and allergen, may be especially dangerous for hairdressers and janitors, who are sometimes exposed to this formaldehyde-releasing
chemical at regular doses for long periods of time.

Quaternium-15 refers to any polymer that has been modified by a process called quaternization.
This process results in changes to molecules that improve the performance of body care products.
Quaternium-15 may also be referred to as quaternary ammonium compounds (QACs) or simply quats.

Quaternium-15 is a known human skin toxicant and allergen and possible eye irritant.
Quaternium-15 is also a formaldehyde-releasing preservative.
Quaternium-15 is often the culprit of skin irritation and allergic reactions.

Quaternium-15 is used in many cosmetics and pharmaceutical preparations.
Quaternium-15 is also used as a preservative in many commercial and industrial products. The table below shows some of the products that may contain quaternium-15.
Hair conditioners, hair styling products, creams, lotions, cleansers, shaving products, eye drops contact solutions and household cleaning products.

Benzalkonium chloride, Quaternium-15, quaternium-15, centrimonium bromide, polyquaternium – followed by a number (i.e. polyquaternium-7).
Polyquaternium refers to any polymer that has been modified by a process called quaternization.
This process results in changes to molecules that improve the performance of body care products.

Polyquaternium may also be referred to as quaternary ammonium compounds (QACs) or simply quats.
Quaternium-15 is an odorless, colorless, water-soluble, antimicrobial agent that is active against bacteria more so than yeast and molds.
Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including cosmetics.

Quaternium-15 is an anti-microbial agent by virtue of being a formaldehyde releaser, however this can also cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin.
In 2005, Quaternium-15 was named in the top 15 most frequently positive allergens identified in patch tests by the North American Contact Dermatitis Group (NACDG).
Sensitivity to Quaternium-15 may be identified with a clinical patch test.

Quaternium-15 is commonly used in personal care products such as cosmetics, soaps, and shampoos.
Quaternium-15 also is found in industrial polishes, waxes, inks, paints, and metal working fluids.
Quaternium-15 belongs to a group of preservatives known as formaldehyde-releasing agents

Quaternium-15 is a quaternary ammonium salt prepared by reaction of hexamethylenetetramine and 1,3-dichloropropene.
Quaternium-15 is a cream-colored powder with a pungent odor.
In addition to its use in cosmetic products, it is also used in the formulation of metal cutting fluids, paints, adhesives, and glues.

Quaternium-15 tension between two components of the product like two liquids or a liquid and a solid.
Lower the surface tension, better mixing capability of that particular ingredient.
Quaternium-15 contains a water-loving end and fat-loving core in a single molecule.

Quaternium-15 attracts dirt, oil, and other impurities accumulated on the surface of the skin with an oil-loving end which then can be washed off easily with water via a water-loving end.
Quaternium-15 also possesses anti-microbial properties.
Quaternium-15 kills the microorganism and stops them from coming back by stopping reproduction.

Quaternium-15 inhibits the growth of molds and fungus in cosmetic products.
Quaternium-15 is also used as an anti-static agent.
Quaternium-15 prevents the build of static charge in the product because of its special chemical structure.

Quaternium-15 is used in formulations of creams, lotions, gels, make-up products, shampoos, baby products, and other skin and hair care products.
Quaternium-15 is a preservative found in a variety of cosmetics, topical pharmaceutical preparations, and industrial substances.
As a preservative, it has activity against bacteria, fungi, and molds.

Quaternium-15 is most frequently found in hair-care products such as conditioners, rinses, and shampoos as well as several popular moisturizing lotions and a number of cosmetic products.
Quaternium-15 is commonly used in personal care products such as cosmetics, soaps, and shampoos.
Quaternium-15 also is found in industrial polishes, waxes, inks, paints, and metal working fluids.

Quaternium-15 belongs to a group of preservatives known as formaldehyde-releasing agents.
Quaternium-15 is a quaternary ammonium salt derived from hexamethylenetetramine; used as a preservative in many cosmetics and industrial substances.
Also acts as a disinfectant and allergenic agent.

Quaternium-15 has a role as a disinfectant and an antibacterial agent.
Quaternium-15 is a quaternary ammonium salt and an organochlorine compound.
Quaternium-15 uses and applications include: Antimicrobial, preservative in adhesives, latex emulsions, paints, cutting fluids, topical pharmaceuticals; preservative in cosmetics, food packaging adhesives, food-contact PU resins; preservative for pigment slurries and latexes used as pigment binders in food-contact paperpaperboard

Quaternium-15 works by releasing formaldehyde, a potent antimicrobial agent.
The formaldehyde released can penetrate the cell walls of microorganisms and disrupt their function, effectively killing them or inhibiting their growth.
Quaternium-15 found in a variety of products including moisturizers, foundations, sunscreens, shampoos, conditioners, and hair dyes.

Quaternium-15 is used in cleaning products and industrial formulations to prevent microbial contamination.
Helps in maintaining the shelf life and efficacy of these products by preventing microbial growth.
Quaternium-15 is known to release formaldehyde, which can cause allergic reactions, contact dermatitis, and other skin irritations.

Due to these health concerns, its use is regulated.
Different regions have set limits on the permissible concentration of Quaternium-15 in products.
The European Union has set a maximum concentration limit of 0.2% in cosmetic products.

The United States Food and Drug Administration (FDA) also monitors its use, but does not have specific concentration limits.
Products containing Quaternium-15 must be labeled appropriately to inform consumers of its presence.
Evidence presented in animal and human studies show that other quaternary ammonium compounds may lead to contact dermatitis.

Quaternium-15 use of products containing quats may contribute significantly to cases of contact dermatitis.
Studies estimate 13 percent[4] to 34 percent of contact dermatitis cases may be linked to quats.
Concentrated solutions of quats may cause burns to the skin as well.

In rare cases, quat use may elicit more severe health symptoms.
Quaternium-15 a study performed on hairdressers, who are routinely exposed to quaternary ammonium compounds in hair products found hairdressers had almost five times as many antibodies to quats.
Increased levels of this antibody relate to an increased risk of allergic reactions to anesthesia, a serious concern since allergic reactions to anesthesia can lead to life-threatening reactions.

A case study reported that a woman suffered from cutaneous cell death after applying a quat-containing antiseptic.
Yet another case study described a man with a pre-existing skin condition who developed dermatitis due to a quaternary ammonium Quaternium-15 in his deodorant, suggesting that quats have the potential to induce sensitivity, especially on damaged skin.
Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many cosmetics and industrial substances.

Quaternium-15 acts as an antimicrobial agent because it acts as a formaldehyde releaser, though doing so can also cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin.
Quaternium-15 can be found under a variety of names, most commonly those of the Dow Chemical Company: Dowicil 200 (cis isomer only), Dowicil 75 and Dowicil 100 (both a mix of cis and trans isomers).
Quaternium-15 can be prepared by reacting hexamethylenetetramine with 1,3-dichloropropene to produce the product as a mixture of cis and trans isomers.

The isolated cis-Quaternium-15 is used primarily in cosmetic applications, with a maximum permitted concentration in the EU of 0.2%.
The mixed product (cis- and trans-) is used in a wider range of formulations such as: emulsifiable metal-cutting fluids; latex and emulsion paints; liquid floor polishes and floor waxes; glues and adhesives.
Quaternium-15 is a formaldehyde-releasing preservative.

Quaternium-15 also is found in industrial polishes, waxes, inks, paints, and metal working fluids.
Quaternium-15 belongs to a group of preservatives known as formaldehyde-releasing agents.
It is a derivative of hexamethylenetetramine chloroallyl chloride.

Quaternium-15 acts as an antimicrobial agent because it slowly releases formaldehyde, which is a preservative with biocidal properties.
Both quaternium-15 and formaldehyde release agents have been the subjects of controversy.
They are often banned in US and Europe.

Quaternium-15 can be found under a variety of names, including Dow Chemical Company: Dowicil 200 (cis isomer only), Dowicil 75 and Dowicil 100 (both a mix of cis and trans isomers).
Quaternium-15 can be prepared by treating hexamethylenetetramine with 1,3-dichloropropene.
A mixture of cis and trans isomers are produced.

Quaternium-15 is a quaternary ammonium compound used as a preservative in many cosmetics and personal care products.
Quaternium-15 functions by releasing formaldehyde, which acts as an antimicrobial agent, helping to prevent the growth of bacteria, fungi, and other microorganisms in the products.
Quaternium-15 is a quaternary ammonium salt that has been used as a surfactant and preservative.

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: White to Pale Yellow
Stability: Stable, but moisture sensitive. Incompatible with strong oxidizing agents.
InChI: InChI=1S/C9H16ClN4.ClH/c10-2-1-3-14-7-11-4-12(8-14)6-13(5-11)9-14;/h1-2H,3-9H2;1H/q+1;/p-1/b2-1-;
InChIKey: UKHVLWKBNNSRRR-ODZAUARKSA-M
SMILES: [N+]12(C/C=C\Cl)CN3CN(CN(C3)C1)C2.[Cl-]

Quaternium-15 belongs to a group of preservatives known as formaldehydereleasing agents.
Quaternium-15 is a cream colored powder with a pungent odor.
1-(cis-3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride, also known as quaternium-15, is used as a preservative in some cosmetics and other industrial products.

Quaternium-15 is included in cosmetic formulations as an antimicrobial agent.
Quaternium-15 is used as a preservative in adhesives and food packaging materials and is regulated by the FDA as an indirect food additive.
Quaternium-15 is also utilized as an antimicrobial agent in water-based metalworking fluids.

Quaternium-15 is a preservative found in many cosmetics and industrial substances that releases formaldehyde.
Quaternium-15 can be found in numerous sources, including but not limited to: mascara, eyeliner, moisturizer, lotion, shampoo, conditioner, nail polish, personal lubricants, soaps, body wash, baby lotion or shampoo, facial cleanser, tanning oil, self-tanning cream, sunscreen, powder, shaving products, ointments, personal wipes or cleansers, wipes, paper, inks, paints, polishes, waxes and industrial lubricants.

Quaternium-15 can cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin, on an infant's skin, or on sensitive areas such as the genitals.
Quaternium-15s chemical formula is C9H16Cl2N4.
Quaternium-15 can be found under a variety of names, including: Dowicil 75; Dowicil 100; Dowco 184; Dowicide Q; 1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride; N-(3-chloroallyl) hexaminium chloride; hexamethylenetetramine chloroallyl chloride; 3,5,7-Triaza-1-azoniaadamantane; 1-(3-chloroallyl)-chloride.

Quaternium-15s CAS number is and its SMILES structure is ClC=C/C[N+]23CN1CN(C3)CN(C2)C1.[Cl-].
Quaternium-15 doesn't occur naturally in the environment.
Quaternium-15 may be used in some self-care products (cosmetics, natural health products, over-the-counter drugs), cleaning products, paints and coatings.

Quaternium-15 's also used in the automotive, aircraft and transportation industry.
Quaternium-15 is a formaldehyde releasing preservative used in personal care products usually cosmetics.
Quaternium-15 is also used as a biocide in household and industrial products.

Quaternium-15 is found in many cosmetics, shampoos and skin care products, as well as in household and industrial products.
Examples of cosmetic products and toiletries are lotions, creams, moisturizers, emollients, foundations, powders, concealers, bronzers, self-tanners, makeup removers, blushes, eye shadows, eyeliners, eyebrow makeup and mascaras and sunscreens as well as shampoos, soaps etc. Adhesives, paper, paperboard, inks, polishes and latex paints may contain Quaternium-15.
Industrial cutting fluid may contain Quaternium-15 as a preservative.

Formaldehyde-releasing preservative used in cosmetics.
Quaternium-15 can aggravate skin, as can all preservatives, although quaternium-15’s ability to do so is very low if the amount in a product is less than 0.2%.
Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including cosmetics.

Helps slow the growth of microorganisms on the skin and opposes the growth of microbes
Inhibits the development of microorganisms in cosmetic products.
Quaternium-15 is a broad-spectrum preservative found in many cosmetics and personal care products.

Quaternium-15 is one of the formaldehyde-releasing preservatives that include imidazolidinyl urea, diazolidinyl urea, 2-bromo-2- nitropropane-l,3-diol, DMDM (dimethylolmethyl)hydantoin, and tris (hydroxymethyl) nitromethane.
Although quaternium-l 5 does release small amounts of formaldehyde, not all patients who are allergic to quaternium-15 are allergic to formaldehyde and vice versa.
Quaternium-15 can cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin, on an infant's skin, or on sensitive areas such as the genitals.

Quaternium-15 releases formaldehyde therefore, repeated use products containing quaternium-15 may cause contact dermatitis.
Can cause skin sensitization leading to allergic contact dermatitis, particularly in individuals with formaldehyde sensitivity.
Inhalation of vapors or dusts containing formaldehyde can cause respiratory irritation and other issues.

Formaldehyde is classified as a human carcinogen by several health organizations, including the International Agency for Research on Cancer (IARC).
Quaternium-15 is not readily biodegradable, and its persistence in the environment can contribute to pollution.
Toxic to aquatic organisms, which can have detrimental effects on aquatic ecosystems.

Due to health and environmental concerns, there is a growing trend to replace Quaternium-15 with safer preservatives.
Quaternium-15 is a commonly used in personal care products such as cosmetics, soaps and shampoos.
Quaternium-15 is readily soluble in water and practically insoluble in mineral oil.

Uses:
Quaternium-15 is used as an antimicrobial preservative in cosmetic, soaps and shampoos. International restrictions 0.1 to 1% - other use; surfactant, hair conditioning, adhesives, binding, lacquers and varnishes.
Commerical use; cutting fluids, lubricants, hydraulic fluids, additives, cleaning, pesticides, bacteriasides, food additives, paper, pharmaceuticals (antiarrhythmic and anticonvulsant agents).

Quaternium-15 is a quaternary ammonium salt derived from hexamethylenetetramine; used as a preservative in many cosmetics and industrial substances. Also acts as a disinfectant and allergenic agent.
Quaternium-15 has a role as a disinfectant, an antibacterial agent, a hapten and an allergen.
Quaternium-15 found in baby shampoos and lotions, although its use in baby products is increasingly scrutinized due to potential sensitization risks.

Included in various household cleaners to prevent bacterial and fungal growth.
Quaternium-15 helps preserve the formulation and effectiveness of the detergent.
Quaternium-15 prevents microbial growth in the product, ensuring it remains effective over time.

Quaternium-15 is used in formulations to enhance antimicrobial efficacy.
Quaternium-15 is used as a preservative to prevent the growth of microbes that can degrade the product.
Prevents microbial contamination, ensuring the adhesive maintains its properties and effectiveness.

Helps preserve the fluid and prevent microbial growth that can cause spoilage and degradation.
Prevents microbial contamination that can affect performance.
Quaternium-15 is used to treat fabrics to prevent microbial growth and odors, enhancing the durability and freshness of the textiles.

Added to paper products to prevent microbial degradation and extend shelf life.
Quaternium-15 is used in formulations to prevent the growth of mold, mildew, and other microorganisms that can damage wood products.
Helps preserve leather products by preventing microbial growth that can cause deterioration.

Quaternium-15 is used as a preservative in some topical pharmaceutical formulations to maintain sterility and efficacy.
Added to food packaging materials to prevent microbial contamination and extend the shelf life of packaged foods.
Quaternium-15 is a quaternary ammonium salt and an organochlorine compound.

Quaternium-15 derives from a hexamethylenetetramine.
Quaternium-15 is an antimicrobial agent used in cosmetics as a cosmetic preservative and antistatic agent.
Formaldehyde-releasing preservative in hand creams, lotions, face creams, shampoos, latex paints, topical medicaments, polishes, metal working fluids, adhesives, inks, etc

Quaternium-15 is used as a preservative and antistatic agent in cosmetics.
Quaternium-15 can be found in a wide variety of products, including eye shadows, foundations, facial powders, body washes, mascaras, shampoos, conditioner, hair colors, facial cleansers, bronzers and nail treatments.
Quaternium-15 is a quaternary ammonium salt used as a preservative in many cosmetics and industrial substances.

Quaternium-15 acts as a formaldehyde releaser.
Quaternium-15 can cause contact dermatitis in sensitive individuals.

Quaternium-15's toxicity is also due to it's ability to react and release formaldehyde and nitrosamines, both of which are believed to be carcinogenic.
Quanternium-15 is a type of preservative which is widely used in many cosmetic and industrial products.

Quaternium-15 may be used as a formaldehyde releaser to investigate the influence of formaldehyde in dermatitis patients with or without contact allergy to formaldehyde through baseline patch test series.
Quaternium-15 is used to preserve water-based formulations against microbial contamination.
Ensures product stability and prevents the growth of bacteria and fungi.

Maintains product efficacy and extends shelf life by preventing microbial growth.
Found in nail polishes and treatments to keep formulations free from microbial contamination.
Quaternium-15 is used in some mouthwashes and toothpastes to prevent bacterial growth, though less common due to oral sensitivity concerns.

Ensures the longevity and effectiveness of cleaning products used on various surfaces.
Preserves the formula to prevent spoilage and maintain cleaning efficacy.
Helps in maintaining the integrity of liquid air fresheners by preventing microbial growth.

Occasionally used in formulations to provide antimicrobial properties.
Quaternium-15 is used in drilling fluids and other formulations to prevent bacterial contamination that can lead to corrosion and other issues.
Found in certain pesticides and fungicides to prevent microbial contamination and enhance stability.

Incorporated into textiles to prevent the growth of odor-causing bacteria and extend the freshness of fabrics used in sportswear, medical garments, and home textiles.
Quaternium-15 is used in the finishing process of textiles to impart antimicrobial properties.
Ensures the integrity of paper-based packaging by preventing microbial growth.

Quaternium-15 is used in the production of specialty papers that require antimicrobial properties, such as medical-grade papers and currency papers.
Applied to wood used in construction to prevent mold and mildew growth, thereby extending the life and durability of the materials.
Used in the preservation of wood furniture to prevent microbial damage and maintain appearance and structural integrity.

Quaternium-15 is used during the tanning process to preserve leather and prevent microbial degradation.
Helps maintain the quality of finished leather goods, including shoes, bags, and jackets, by preventing mold and mildew.
Occasionally used in eye drops to prevent microbial contamination, though alternatives are preferred due to sensitivity concerns.

Used in some topical medications to maintain sterility and efficacy over time.
Quaternium-15 is used in the production of antimicrobial films for food packaging to extend the shelf life of perishable goods by preventing microbial contamination.
Added to plastic and other materials used for food storage to prevent the growth of bacteria and fungi.

Quaternium-15 is used in certain inks and dyes to prevent microbial growth that can affect the quality and consistency of the products.
Helps maintain the integrity of sealants and caulks by preventing microbial degradation.
Found in some automotive cleaning and maintenance products to preserve formulations and prevent microbial growth.

Quaternium-15 is used in cleaning products for electronics to prevent microbial contamination and ensure product efficacy.
Quaternium-15 is a formaldehyde-releasing preservative in hand creams, lotions, face creams, shampoos, latex paints, topical medicaments, polishes, metal-working fluids, adhesives, inks, etc.; quatemium-15.
Prevents microbial contamination and extends the shelf life.

Quaternium-15 acts as a preservative to prevent the growth of bacteria and fungi.
Found in foundations, powders, and eyeliners to maintain product integrity.
Quaternium-15 is used to preserve formulations against microbial growth.

Quaternium-15 is used in a wide variety of cosmetic products as a surfactant and preservative.
As a surfactant, Quaternium-15 lowers the surface.
Quaternium-15 may be used as a formaldehyde releaser to investigate the influence of formaldehyde in dermatitis patients with or without contact allergy to formaldehyde through baseline patch test series.

Quaternium-15 is a quaternary ammonium salt used as a preservative in many cosmetics and industrial substances.
Quaternium-15 acts as a formaldehyde releaser.
Preservative in cosmetics, hair care products, soaps, adhesives.

Safety Profile:
Prolonged exposure to products containing Quaternium-15 can lead to skin irritation, even in individuals who are not formally allergic.
This can manifest as dryness, itching, and rash.
Inhalation of vapors or dust containing Quaternium-15 can irritate the respiratory tract, leading to symptoms such as coughing, sneezing, and throat irritation.

People with asthma or other respiratory conditions may experience exacerbated symptoms upon exposure.
Quaternium-15 can cause allergic contact dermatitis in sensitive individuals.

Symptoms include redness, itching, and inflammation of the skin.
People sensitive to formaldehyde may experience more severe reactions, including hives and blistering.

QUATERNIUM-18, N° CAS : 61789-80-8, Origine(s) : Synthétique. Nom INCI : QUATERNIUM-18, N° EINECS/ELINCS : 263-090-2. Classification : Ammonium quaternaire, Libérateur de Formaldéhyde. Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation. Noms français : DIHYDROGENATEDTALLOW DIMETHYL AMMONIUM CHLORIDE; N,N-DIHYDROGENATEDTALLOW N,N-DIMETHYL AMMONIUM CHLORIDE Noms anglais : BIS(HYDROGENATED TALLOW)DIMETHYLAMMONIUM CHLORIDE; QUATERNARY AMMONIUM COMPOUNDS, BIS(HYDROGENATED TALLOW ALKYL)DIMETHYL, CHLORIDES. Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides; bis(hydrogenated tallow alkil)dimethyl, chlorides; Bis(hydrogenated tallow alkyl)dimethylammonium chlorides; Distearyldimethylammonium chloride; N,N-Dimethyl-N,N-di-n-alkyl(C16-18)-ammoniumchloride; Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl chlorides. 107-64-2 [RN] 1-Octadecanaminium, N,N-dimethyl-N-octadecyl-, chloride (1:1) [ACD/Index Name] 203-508-2 [EINECS] Aliquat 207 Ammonium, dimethyldioctadecyl-, chloride BQ1923000 Chlorure de N,N-diméthyl-N-octadécyl-1-octadécanaminium [French] [ACD/IUPAC Name] Dimethyl dioctadecyl ammonium chloride DIMETHYL DIOCTADECYLAMMONIUM CHLORIDE Dimethyldioctadecylammonium chloride [Wiki] Dimethyldistearylammonium Chloride Di-n-octadecyldimethylammonium chloride dioctadecyl dimethyl ammonium chloride dioctadecyldimethylammonium chloride Distearyl dimethylammonium chloride DISTEARYLDIMETHYLAMMONIUM CHLORIDE Distearyldimonium chloride DODAC MFCD00055540 [MDL number] N,N-Dimethyl-N-octadecyl-1-octadecanaminium chloride [ACD/IUPAC Name] N,N-Dimethyl-N-octadecyl-1-octadecanaminiumchlorid [German] [ACD/IUPAC Name] N,N-Dimethyl-N-octadecyloctadecan-1-aminium chloride OM9573ZX3X [107-64-2] 12677-13-3 [RN] 129119-79-5 [RN] 134191-39-2 [RN] 14357-21-2 [RN] 1-Octadecanaminium, N,N-dimethyl-N-octadecyl-, chloride 263-090-2 [EINECS] 59111-82-9 [RN] 61789-80-8 [RN] 66359-86-2 [RN] 76723-98-3 [RN] Adogen TA 100 Ammonyx 2200P100 Arosurf TA 100 Arosurf TA-100 Arquad 218-100 Arquad 218-100P Arquad R 40 Cation DS Cedequat TD 75 Dehyquart DAM Dimethyl distearylammonium chloride dimethyl(dioctadecyl)azanium and chloride Dimethyldi-n-octadecylammonium chloride dimethyldioctadecylamine, chloride dimethyl-dioctadecylammonium chloride dimethyl-dioctadecyl-ammonium chloride dimethyldioctadecylammoniumchloride dimethyl-dioctadecylazanium chloride dimethyl-dioctadecyl-azanium chloride DIMETHYLDIOCTADECYLAZANIUM CHLORIDE dimethyl-distearyl-ammonium chloride Dioctadecyldimethylammoniumchloride Distearyl dimethyl ammonium chloride DODA(Cl) EINECS 203-508-2 Genamin DSAC Jsp000681 Kemamine Q 9702CLP N,N-dimethyl-dioctadecyl ammonium chloride N,N-Dimethyl-N-octadecyl-1-octadecanaminiumchloride N,N-Dioctadecyl-N,N-dimethylammonium chloride Q-D 86P Quartamin D 86 Quartamin DM 86P Quaternium 5 QUATERNIUM-18 Quaternium-5 Sokalan 9200 Surfroyal DSAC Talofloc Varisoft 100 Varisoft TA 100

QUATERNIUM-22, N° CAS : 51812-80-7 / 82970-95-4. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-22. Nom chimique : 3-(D-Gluconoylamino)propyl(2-hydroxyethyl)dimethylammonium chloride. N° EINECS/ELINCS : 257-440-3. Classification : Ammonium quaternaire. Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface, Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. -(D-gluconoylamino)propyl(2-hydroxyethyl)dimethylammonium chloride; (2-hydroxyethyl)dimethyl{3-[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanamido]propyl}azanium chloride; 1-Propanaminium, 3-(D-gluconoylamino)-N-(2-hydroxyethyl)-N,N-dimethyl-, chloride; CERAPHYL® 60 (ca. 60% substance in water). Jump to main contentJump to site nav Home About us Web APIs Help Sign in ChemSpider Search and share chemistry Search ChemSpider For medical information relating to Covid-19, please consult the World Health Organisation or local healthcare provision. Simple Structure Advanced History Found 1 result Search term: 51812-80-7 (Found by approved synonym) COMMENT ON THIS RECORD ChemSpider 2D Image | QUATERNIUM-22 | C13H29ClN2O7Save3DZoom QUATERNIUM-22 Molecular FormulaC13H29ClN2O7 Average mass360.832 Da Monoisotopic mass360.166321 Da ChemSpider ID36681 defined stereocentres - 4 of 4 defined stereocentres More details: This record has not been tagged. TAG Names Properties Searches Spectra Vendors Articles More Names and SynonymsDatabase ID(s) Validated by Experts, Validated by Users, Non-Validated, Removed by Users 257-440-3 [EINECS] 51812-80-7 [RN] Chlorure de N-(2-hydroxyéthyl)-N,N-diméthyl-3-{[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]amino}-1-propanaminium [French] [ACD/IUPAC Name] Chlorure de N-(2-hydroxyéthyl)-N,N-diméthyl-3-{[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]amino}-1-propanaminium (non-preferred name) [French] [ACD/IUPAC Name] N-(2-Hydroxyethyl)-N,N-dimethyl-3-{[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]amino}-1-propanaminium chloride [ACD/IUPAC Name] N-(2-Hydroxyethyl)-N,N-dimethyl-3-{[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]amino}-1-propanaminium chloride (non-preferred name) [ACD/IUPAC Name] N-(2-Hydroxyethyl)-N,N-dimethyl-3-{[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]amino}-1-propanaminiumchlorid [German] [ACD/IUPAC Name] N-(2-Hydroxyethyl)-N,N-dimethyl-3-{[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]amino}-1-propanaminiumchlorid (non-preferred name) [German] [ACD/IUPAC Name] QUATERNIUM-22 (2-HYDROXYETHYL)DIMETHYL{3-[(2R,3S,4R,5R)-2,3,4,5,6-PENTAHYDROXYHEXANAMIDO]PROPYL}AZANIUM CHLORIDE (α-Gluconamidopropyl)dimethyl-2-hydroxyethylammonium chloride [51812-80-7] 149358-34-9 [RN] 1-Propanaminium, 3-(D-gluconoylamino)-N-(2-hydroxyethyl)-N,N-dimethyl-, chloride 3-(D-Gluconoylamino)-N-(2-hydroxyethyl)-N,N-dimethyl-1-propanamin- ium chloride 3-(D-Gluconoylamino)propyl(2-hydroxyethyl)dimethylammonium chloride 82970-95-4 [RN] N-(2-Hydroxyethyl)-N,N-dimethyl-3-{[(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoyl]amino}-1-propanaminiumchloride QUATERNIUM 22 γ-Gluconamidopropyl dimethyl 2-hydroxyethyl ammonium chloride

Decyldimethyloctylammonium chloride; Decyldimethyloctylammonium chloride; Decyldimethyloctylammonium chloride; Decyldimethyloctylammonium chloride; Octyl decyl dimethyl ammonium chloride; QUATERNIUM-24, N° CAS : 32426-11-2, Origine(s) : Synthétique. Nom INCI : QUATERNIUM-24. Nom chimique : Decyldimethyloctylammonium chloride. N° EINECS/ELINCS : 251-035-5, Classification : Ammonium quaternaire. Ses fonctions (INCI) : Antimicrobien : Aide à ralentir la croissance de micro-organismes sur la peau et s'oppose au développement des microbes, Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface, Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation. Noms français : 1-DECANAMINIUM, N,N-DIMETHYL-N-OCTYL-, CHLORIDE; Chlorure de décyldiméthyloctylammonium; DECYLOCYTLDIMETHYLAMMONIUM CHLORIDE. OCTYL DECYL DIMETHYL AMMONIUM CHLORIDE. Noms anglais : 1-Decaminium N-octyl-N,N-dimethyl-, chloride; Decyldimethyloctylammonium chloride; Decyldimethyloctylammonium chloride; Decyldimethyloctylammonium chloride; Decyldimethyloctylammonium chloride; Octyl decyl dimethyl ammonium chloride; 1-Decanaminium, N,N-dimethyl-N-octyl-, chloride (1:1) [ACD/Index Name] ; 251-035-5 [EINECS] ; 32426-11-2 [RN]; Chlorure de N,N-diméthyl-N-octyl-1-décanaminium [French] [ACD/IUPAC Name]; Decyloctyldimethylammonium chloride; N,N-Dimethyl-N-octyl-1-decanaminium chloride [ACD/IUPAC Name]; N,N-Dimethyl-N-octyl-1-decanaminiumchlorid [German] [ACD/IUPAC Name]; N,N-Dimethyl-N-octyldecan-1-aminium chloride; Quaternium-24 ; 1-Decaminium, N-octyl-N,N-dimethyl-, chloride; 1-Decanaminium, N,N-dimethyl-N-octyl-, chloride; Ammonium, decyldimethyloctyl, chloride; Decyl dimethyl octyl ammonium chloride; decyl-dimethyl-octylammonium chloride; decyl-dimethyl-octyl-ammonium chloride; DECYLDIMETHYLOCTYLAMMONIUM CHLORIDE; decyl-dimethyl-octylazanium and chloride; decyl-dimethyl-octylazanium chloride; decyl-dimethyl-octyl-azanium chloride; DECYLDIMETHYLOCTYLAZANIUM CHLORIDE; decyl-dimethyl-octylazanium;chloride; Decylocytldimethylammonium chloride ; Di-(Octyl-decyl)dimethylammonium chloride; EINECS 251-035-5; N,N-Dimethyl-N-octyl-1-decanaminiumchloride; N-Octyl-N-decyl-N-dimethylammonium chloride; N-Octyl-N-decyl-N-dimethyl-ammonium chloride; Octyl Decyldimethyl Ammonium Chloride; Quaternium 24

QUATERNIUM-26, N° CAS : 68953-64-0 / 64156-20-3, Origine(s) : Synthétique. Nom INCI : QUATERNIUM-26, N° EINECS/ELINCS : 273-222-0. Classification : Ammonium quaternaire Ses fonctions (INCI). Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. 1-Propanaminium, 3-amino-N-(2-hydroxyethyl)-N,N-dimethyl-, N-mink-oil acyl derivs., chlorides; EC Inventory, ; 1-Propanaminium, 3-amino-N-(2-hydroxyethyl)-N,N-dimethyl-, N-mink-oil acyl derivs, chlorides; CERAPHYL 65 ; Quaternium-26

QUATERNIUM-27, N° CAS : 68122-86-1. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-27. N° EINECS/ELINCS : 268-531-2. Classification : Ammonium quaternaire. Ses fonctions (INCI), Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Noms français : Méthylsulfate de composés imidazolium du dihydro-4,5 méthyl-1 alkyle de suif nor-2 (amidoéthyl-2 de suif)-1 Noms anglais : 1-(2-TALLOW AMIDOETHYL)-1-METHYL-2-NOR(TALLOW ALKYL)-2-IMIDAZOLINIUM METHYL SULFATE 1-(2-TALLOWAMIDOETHYL)-1-METHYL-2-TALLOWALKYLIMIDAZOLINIUM METHYLSULFATE 1-METHYL-1-(2-TALLOWAMIDOETHYL)-2-TALLOWIMIDAZOLINIUM METHYLSULFATE 1-METHYL-1-TALLOWALKYLAMIDOETHYL-2-TALLOWALKYLIMIDAZOLINE METHOSULFATE IMIDAZOLIUM COMPOUNDS, 4,5-DIHYDRO-1-METHYL-2-NORTALLOW ALKYL-1-(2-TALLOW AMIDOETHYL), ME SULFATES; Imidazolium compounds, 4,5-dihydro-1-methyl-2-nortallow alkyl-1-(2-tallow amidoethyl), Me sulfates.

QUATERNIUM-33, N° CAS : 72102-40-0 / 86221-07-0, Origine(s) : Synthétique, Nom INCI : QUATERNIUM-33, N° EINECS/ELINCS : 276-339-5. Classification : Ammonium quaternaire: Ses fonctions (INCI). Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. 1-Propanaminium, 3-amino-N-ethyl-N,N-dimethyl-, N-lanolin acyl derivs., Et sulfates; Lanolin acids, APMA amide, di-Et sulfate; Quaternium-33; iso and antiso C10-40 AAP EDM-ES

QUATERNIUM-45; N° CAS : 21034-17-3; Origine(s) : Synthétique; Nom INCI : QUATERNIUM-45; Nom chimique : 3,4-Dimethyl-2-[2-(phenylamino)vinyl]oxazolium iodide; N° EINECS/ELINCS : 244-158-0; Classification : Ammonium quaternaire. Ses fonctions (INCI). 3,4-dimethyl-2-[2-(phenylamino)vinyl]oxazolium iodide. : 3,4-dimethyl-2-[(E)-2-(phenylamino)ethenyl]-1,3-oxazol-3-ium iodide. Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. 2-[(E)-2-Anilinovinyl]-3,4-dimethyl-1,3-oxazol-3-ium iodide [ACD/IUPAC Name] ; 2-[(E)-2-Anilinovinyl]-3,4-dimethyl-1,3-oxazol-3-iumiodid [German] [ACD/IUPAC Name]; 244-158-0 [EINECS]; Iodure de 2-[(E)-2-anilinovinyl]-3,4-diméthyl-1,3-oxazol-3-ium [French] [ACD/IUPAC Name]; Oxazolium, 3,4-dimethyl-2-[(E)-2-(phenylamino)ethenyl]-, iodide (1:1) [ACD/Index Name]; 21034-17-3 [RN]; 3,4-Dimethyl-2-(2-(phenylamino)vinyl)oxazolium iodide; 3,4-DIMETHYL-2-[2-(PHENYLAMINO)ETHENYL]-1,3-OXAZOL-3-IUM IODIDE; 3,4-dimethyl-2-[2-(phenylamino)vinyl]oxazolium iodide; Kankohso 401; Kankohso 401 [Japanese]; Oxazolium, 2-(2-anilinovinyl)-3,4-dimethyl-, iodide; Oxazolium, 3,4-dimethyl-2-(2-(phenylamino)ethenyl)-, iodide (9CI); Quaternium-45

QUATERNIUM-51; N° CAS : 1463-95-2; Origine(s) : Synthétique; Nom INCI : QUATERNIUM-51; N° EINECS/ELINCS : 215-976-5. Classification : Ammonium quaternaire; 2-[2-[(5-bromo-2-pyridyl)amino]vinyl]-1-ethyl-6-methylpyridinium iodide; : 2-[(E)-2-[(5-bromopyridin-2-yl)amino]ethenyl]-1-ethyl-6-methylpyridin-1-ium iodide. Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. 2-{(E)-2-[(5-Brom-2-pyridinyl)amino]vinyl}-1-ethyl-6-methylpyridiniumiodid [German] [ACD/IUPAC Name]; 2-{(E)-2-[(5-Bromo-2-pyridinyl)amino]vinyl}-1-ethyl-6-methylpyridinium iodide [ACD/IUPAC Name]; 2-{(E)-2-[(5-Bromopyridin-2-yl)amino]vinyl}-1-ethyl-6-methylpyridinium iodide ;215-976-5 [EINECS]; Iodure de 2-{(E)-2-[(5-bromo-2-pyridinyl)amino]vinyl}-1-éthyl-6-méthylpyridinium [French] [ACD/IUPAC Name]; Pyridinium, 2-[(E)-2-[(5-bromo-2-pyridinyl)amino]ethenyl]-1-ethyl-6-methyl-, iodide (1:1) [ACD/Index Name]; 1463-95-2 [RN]; 2-(2-((5-Bromo-2-pyridyl)amino)vinyl)-1-ethyl-6-methylpyridinium iodide; 2-[(E)-2-[(5-BROMOPYRIDIN-2-YL)AMINO]ETHENYL]-1-ETHYL-6-METHYLPYRIDIN-1-IUM IODIDE; 2-[2-[(5-bromo-2-pyridyl)amino]vinyl]-1-ethyl-6-methylpyridinium iodide; Pyridinium, 2-(2-((5-bromo-2-pyridinyl)amino)ethenyl)-1-ethyl-6-methyl-, iodide ;Pyridinium,2-[2-[(5-bromo-2-pyridinyl)amino]ethenyl]-1-ethyl-6-methyl-, iodide (1:1); Quaternium-51

QUATERNIUM-52, N° CAS : 58069-11-7. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-52. Classification : Ammonium quaternaire. Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface, Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance, Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation. Poly(oxy-1,2-ethanediyl), α,α',α''-[(octadecylnitrilio)tri-2,1-ethanediyl]tris[ω-hydroxy-, phosphate (1:1); Talgaminphosphat, ethoxyliert

QUATERNIUM-53; N° CAS : 68410-69-5; Origine(s) : Synthétique; Nom INCI : QUATERNIUM-53; N° EINECS/ELINCS : 268-762-9; Classification : Ammonium quaternaire. Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Noms français : Méthylsulfate de dérivés méthylés de suif et de diéthylènetriamine,polyéthoxylés. Noms anglais :METHYL TALLOW DIETHYLENETRIAMINE CONDENSATE, POLYETHOXYLATED, METHYL SULFATE; Poly(oxy-1,2-ethanediyl),alpha-(2-(bis(2-aminoethyl)methylammonio- )ethyl)-omega-hydroxy, N,N'-ditallow acyl derivs, methyl sulfates; ; Noms français : Méthylsulfate de dérivés méthylés de suif et de diéthylènetriamine,polyéthoxylés. Noms anglais : METHYL TALLOW DIETHYLENETRIAMINE CONDENSATE, POLYETHOXYLATED, METHYL SULFATE; Poly(oxy-1,2-ethanediyl),alpha-(2-(bis(2-aminoethyl)methylammonio- )ethyl)-omega-hydroxy, N,N'-ditallow acyl derivs, methyl sulfates

QUATERNIUM-60 Origine(s) : Synthétique Nom INCI : QUATERNIUM-60 Classification : Ammonium quaternaire Ses fonctions (INCI) Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance

QUATERNIUM-70; N° CAS : 68921-83-5; Origine(s) : Synthétique; Nom INCI : QUATERNIUM-70; Nom chimique : Dimethyl[3-[(1-oxooctadecyl)amino]propyl][2-oxo-2-(tetradecyloxy)ethyl]ammonium chloride; N° EINECS/ELINCS : 272-964-2; Classification : Ammonium quaternaire; Ses fonctions (INCI): Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface ; Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Dimethyl[3-[(1-oxooctadecyl)amino]propyl][2-oxo-2-(tetradecyloxy)ethyl]ammonium chloride; Ceraphyl 70 ; dimethyl(3-octadecanamidopropyl)[2-oxo-2-(tetradecyloxy)ethyl]azanium chloride; 1-Propanaminium, N,N-dimethyl-3-[(1-oxooctadecyl)amino]-; N-[2-oxo-2-(tetradecyloxy)ethyl]-, chloride (1:1) [ACD/Index Name]; 272-964-2 [EINECS]; 68921-83-5 [RN]; Chlorure de N,N-diméthyl-N-[2-oxo-2-(tétradécyloxy)éthyl]-3-(stearoylamino)-1-propanaminium [French] [ACD/IUPAC Name]; N,N-Dimethyl-N-[2-oxo-2-(tetradecyloxy)ethyl]-3-(stearoylamino)-1-propanaminium chloride [ACD/IUPAC Name]; N,N-Dimethyl-N-[2-oxo-2-(tetradecyloxy)ethyl]-3-(stearoylamino)-1-propanaminiumchlorid [German] [ACD/IUPAC Name]; N,N-Dimethyl-N-[2-oxo-2-(tetradecyloxy)ethyl]-3-(stearoylamino)propan-1-aminium chloride; Quaternium-70; (2-keto-2-myristyloxy-ethyl)-dimethyl-(3-stearamidopropyl)ammonium chloride; (3-Stearamidopropyl)dimethylmyristoyloxycarbonylmethylammonium chloride ; 1-Propanaminium, N,N-dimethyl-3-((1-oxooctadecyl)amino)-N-(2-oxo-2-(tetradecenylox- y)ethyl)-, chloride; 1-Propanaminium, N,N-dimethyl-3-((1-oxooctadecyl)amino)-N-(2-oxo-2-(tetradecyloxy)ethyl)-, chloride; Dimethyl(3-((1-oxooctadecyl)amino)propyl)(2-oxo-2-(tetradecyloxy)ethyl)ammonium chloride; DIMETHYL(3-OCTADECANAMIDOPROPYL)[2-OXO-2-(TETRADECYLOXY)ETHYL]AZANIUM CHLORIDE; dimethyl-[3-(1-oxooctadecylamino)propyl]-(2-oxo-2-tetradecoxyethyl)ammonium chloride; dimethyl-[3-(octadecanoylamino)propyl]-(2-oxo-2-; tetradecoxy-ethyl)ammonium chloride; dimethyl-[3-(octadecanoylamino)propyl]-(2-oxo-2-tetradecoxyethyl)azanium chloride; dimethyl-[3-(octadecanoylamino)propyl]-(2-oxo-2-tetradecoxy-ethyl)azanium chloride; dimethyl[3-[(1-oxooctadecyl)amino]propyl][2-oxo-2-(tetradecyloxy)ethyl]ammonium chloride, EINECS 272-964-2; N,N-Dimethyl-3-((1-oxooctadecyl)amino)-N-(2-oxo-2-(tetradecenylox- y)ethyl)-1-propanaminium chloride; Stearamidopropyl dimethyl (myristyl acetate) ammonium chloride

QUATERNIUM-73; N° CAS : 15763-48-1; Origine(s) : Synthétique; Nom INCI : QUATERNIUM-73; Nom chimique : 3-Heptyl-2-[(3-heptyl-4-methyl-3H-thiazol-2-ylidene)methyl]-4-methylthiazolium iodide; 3-heptyl-2-[(3-heptyl-4-methyl-3H-thiazol-2-ylidene)methyl]-4-methylthiazolium iodide; 3-heptyl-2-{[(2Z)-3-heptyl-4-methyl-2,3-dihydro-1,3-thiazol-2-ylidene]methyl}-4-methyl-1,3-thiazol-3-ium iodide; N° EINECS/ELINCS : 239-852-5. Classification : Ammonium quaternaire; Ses fonctions (INCI). Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surfa. 239-852-5 [EINECS] 3-Heptyl-2-[(3-heptyl-4-methyl-1,3-thiazol-2(3H)-ylidene)methyl]-4-methyl-1,3-thiazol-3-ium iodide 3-Heptyl-2-[(E)-(3-heptyl-4-methyl-1,3-thiazol-2(3H)-yliden)methyl]-4-methyl-1,3-thiazol-3-iumiodid [German] [ACD/IUPAC Name] 3-Heptyl-2-[(E)-(3-heptyl-4-methyl-1,3-thiazol-2(3H)-ylidene)methyl]-4-methyl-1,3-thiazol-3-ium iodide [ACD/IUPAC Name] Iodure de 3-heptyl-2-[(E)-(3-heptyl-4-méthyl-1,3-thiazol-2(3H)-ylidène)méthyl]-4-méthyl-1,3-thiazol-3-ium [French] [ACD/IUPAC Name] thiazolium, 3-heptyl-2-[(3-heptyl-4-methyl-2(3H)-thiazolylidene)methyl]-4-methyl-, iodide (1:1) Thiazolium, 3-heptyl-2-[(E)-(3-heptyl-4-methyl-2(3H)-thiazolylidene)methyl]-4-methyl-, iodide (1:1) [ACD/Index Name] 15763-48-1 [RN] 3-Heptyl-2-((3-heptyl-4-methyl-3H-thiazol-2-ylidene)methyl)-4-methylthiazolium iodide 3-Heptyl-2-((3-heptyl-4-methyl-4-thiazolin-2-ylidene)methyl)-4-methylthiazolium iodide 3-HEPTYL-2-[(3-HEPTYL-4-METHYL-1,3-THIAZOL-2-YLIDENE)METHYL]-4-METHYL-1,3-THIAZOL-3-IUM IODIDE 3-heptyl-2-[(3-heptyl-4-methyl-3H-thiazol-2-ylidene)methyl]-4-methylthiazolium iodide 3-HEPTYL-2-{[(2E)-3-HEPTYL-4-METHYL-1,3-THIAZOL-2-YLIDENE]METHYL}-4-METHYL-1,3-THIAZOL-3-IUM IODIDE Kankohso 201 MFCD01680792 Pionin Quaternium 73 QUATERNIUM-73 Thiazolium, 3-heptyl-2-((3-heptyl-4-methyl-2(3H)-thiazolylidene)methyl)-4-methyl-, iodide Thiazolium, 3-heptyl-2-((3-heptyl-4-methyl-4-thiazolin-2-ylidene)methyl)-4-methyl-, iodide

QUATERNIUM-75 Origine(s) : Synthétique Nom INCI : QUATERNIUM-75 Classification : Ammonium quaternaire Ses fonctions (INCI) Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance

QUATERNIUM-8; Origine(s) : Synthétique; Nom INCI : QUATERNIUM-8. Classification : Ammonium quaternaire. Ses fonctions (INCI); Antimicrobien : Aide à ralentir la croissance de micro-organismes sur la peau et s'oppose au développement des microbes. Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance; It helps make drying easier, whilst it totally respects hair structure. It protects the hair from the heat damage caused by hairdryer or hair iron, as well from mechanical stress. It has softening, conditioning and antistatic proprieties.

QUATERNIUM-80, N° CAS : 134737-05-6. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-80. Classification : Ammonium quaternaire. Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface : Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Quaternium-80 is the quaternary ammonium salt with the alkyl groups derived from coconut oil; Siloxanes and Silicones, di-Me, 3-[3-[(3-coco amidopropyl)dimethylammonio]-2-hydroxypropoxy]propyl group-terminated, acetates (salts); Siloxanes and silicones, di-Me, 3-{3-[(3-Cocoamidopropyl) -dimethylammonia]-2-hydroxy-propoxy}propyl group terminated, acetates (salts)

QUATERNIUM-82, N° CAS : 65059-61-2 / 173833-36-8. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-82. N° EINECS/ELINCS : 265-339-0 / -. Classification : Ammonium quaternaire. Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. [2-[bis(2-hydroxypropyl)amino]ethyl]bis(2-hydroxypropyl)(methyl)ammonium methyl sulphate, dioleate (ester); (2-hydroxypropyl)({2-[(2-hydroxypropyl)({2-[(9E)-octadec-9-enoyloxy]propyl})amino]ethyl})methyl({2-[(10E)-octadec-10-enoyloxy]propyl})azanium methyl sulfate; 2-Hydroxy-N-{2-[(2-hydroxypropyl){2-[(9E)-9-octadecenoyloxy]propyl}amino]ethyl}-N-methyl-N-{2-[(10E)-10-octadecenoyloxy]propyl}-1-propanaminium methyl sulfate [ACD/IUPAC Name] 2-Hydroxy-N-{2-[(2-hydroxypropyl){2-[(9E)-9-octadecenoyloxy]propyl}amino]ethyl}-N-methyl-N-{2-[(10E)-10-octadecenoyloxy]propyl}-1-propanaminiummethylsulfat [German] [ACD/IUPAC Name] Sulfate de 2-hydroxy-N-{2-[(2-hydroxypropyl){2-[(9E)-9-octadecenoyloxy]propyl}amino]éthyl}-N-méthyl-N-{2-[(10E)-10-octadecenoyloxy]propyl}propane et de méthyle [French] [ACD/IUPAC Name] (2-(Bis(2-hydroxypropyl)amino)ethyl)bis(2-hydroxypropyl)(methyl)ammonium methyl sulphate, dioleate (ester) (2-HYDROXYPROPYL)({2-[(2-HYDROXYPROPYL)({2-[(9E)-OCTADEC-9-ENOYLOXY]PROPYL})AMINO]ETHYL})METHYL({2-[(10E)-OCTADEC-10-ENOYLOXY]PROPYL})AZANIUM METHYL SULFATE(1-) 1-Propanaminium, N-(2-(bis(2-hydroxypropyl)amino)ethyl)-2-hydroxy-N-(2-hydroxypropyl)-N-methyl-, di-(9Z)-9-octadecenoate (ester), methyl sulfate (salt) 265-339-0 [EINECS] 65059-61-2 [RN]

QUATERNIUM-83, N° CAS : 91723-55-6. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-83. N° EINECS/ELINCS : 294-563-1. Classification : Ammonium quaternaire. Ses fonctions (INCI): Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance

QUATERNIUM-87, N° CAS : 92201-88-2. Origine(s) : Synthétique. Nom INCI : QUATERNIUM-87. N° EINECS/ELINCS : 931-745-8. Classification : Ammonium quaternaire. Ses fonctions (INCI): Agent nettoyant : Aide à garder une surface propre. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation

QUATERNIUM-88, Origine(s) : Synthétique. Nom INCI : QUATERNIUM-88. Classification : Ammonium quaternaire. Ses fonctions (INCI). Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance

QUATERNIUM-89 Origine(s) : Synthétique Nom INCI : QUATERNIUM-89 Classification : Ammonium quaternaire Ses fonctions (INCI) Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance

QUATERNIUM-90, Origine(s) : Synthétique, Nom INCI : QUATERNIUM-90. Classification : Ammonium quaternaire. Ses fonctions (INCI). Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface

QUATERNIUM-91 Origine(s) : Synthétique Nom INCI : QUATERNIUM-91 Classification : Ammonium quaternaire Ses fonctions (INCI) Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance

QUATERNIUM-95; N° CAS : 1030827-59-8; Origine(s) : Synthétique; Nom INCI : QUATERNIUM-95. Classification : Ammonium quaternaire. Ses fonctions (INCI). Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Absorbant UV : Protège le produit cosmétique contre les effets de la lumière UV

QUATERNIUM-96, Origine(s) : Synthétique. Nom INCI : QUATERNIUM-96. Classification : Ammonium quaternaire. Ses fonctions (INCI). Agent nettoyant : Aide à garder une surface propre. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation

SYNONYMS C.I.Acid Yellow 3; C.I. 47005; Quinoline Yellow, water soluble; Food Yellow 13; Sodium 2-(1,3-dioxoindan-2-yl)quinolinedisulfonate; 2-(1,3-Dioxoindan-2-yl) quinolinedisulfonic acid sodium salt; Sodium 2-(2-quinolyl) indan-1,3-dione-disulfonates; Quinoline Yellow;CAS NO 8004-92-0

Quercetin is a flavonoid found naturally in many fruits, vegetables, and grains, known for its powerful antioxidant, anti-inflammatory, and immune-boosting properties.
Quercetin is widely recognized for its ability to neutralize free radicals, reduce inflammation, and support cardiovascular health, making it a valuable ingredient in dietary supplements, skincare products, and wellness formulations.
This versatile compound offers numerous health benefits, including enhanced immune defense, reduced allergy symptoms, and protection against oxidative stress.

CAS Number: 117-39-5
EC Number: 204-187-1

Synonyms: Quercetin, Quercetin Dihydrate, Quercetol, Sophoretin, Meletin, Quercetine, Quercetin Bioflavonoid, 3,3',4',5,7-Pentahydroxyflavone, Quercetin Phytocomplex, Quercetin Bioactive, Quercetol Phytocomplex, Flavonoid Quercetin



APPLICATIONS


Quercetin is extensively used in dietary supplements for its antioxidant properties, providing support for neutralizing free radicals and reducing oxidative stress, which contributes to overall health and longevity.
Quercetin is favored in the formulation of immune-boosting supplements, where it enhances the body’s natural defenses and helps reduce the duration and severity of colds and infections.
Quercetin is utilized in allergy-relief supplements, offering natural antihistamine effects that help reduce allergy symptoms such as sneezing, congestion, and itchy eyes.

Quercetin is widely used in cardiovascular health supplements, where it supports healthy blood circulation, reduces blood pressure, and helps to lower LDL cholesterol levels.
Quercetin is employed in the creation of anti-inflammatory supplements, providing relief from chronic inflammation and supporting overall joint health.
Quercetin is essential in the development of sports recovery supplements, where it helps reduce muscle soreness and enhance athletic performance by decreasing oxidative stress in the muscles.

Quercetin is utilized in the production of respiratory health products, offering benefits for reducing asthma symptoms and improving lung function, particularly in individuals with chronic respiratory issues.
Quercetin is a key ingredient in wellness products designed to support healthy aging, where it helps protect cells from oxidative damage and promotes longevity.
Quercetin is used in the development of weight management supplements, where it supports fat metabolism and helps regulate glucose levels, making it a valuable component in managing obesity and metabolic disorders.

Quercetin is applied in the formulation of skincare products for its anti-aging and anti-inflammatory benefits, offering protection against UV-induced skin damage and helping to reduce redness, irritation, and inflammation.
Quercetin is employed in the production of creams and lotions for sensitive skin, providing antioxidant protection while soothing irritation and helping to repair damaged skin.
Quercetin is used in wellness supplements to support brain health, providing neuroprotective benefits and helping to improve cognitive function and memory by reducing oxidative stress in the brain.

Quercetin is widely utilized in the creation of detox products, where it helps to eliminate toxins and support liver function, contributing to overall wellness and vitality.
Quercetin is a key component in supplements designed to support vascular health, helping to strengthen blood vessels, improve circulation, and reduce the risk of cardiovascular diseases.
Quercetin is used in the production of eye health supplements, providing antioxidant support to protect the eyes from oxidative stress and helping to reduce the risk of cataracts and age-related macular degeneration.

Quercetin is employed in the formulation of supplements that support metabolic health, helping to regulate blood sugar levels and improve insulin sensitivity.
Quercetin is applied in natural remedies for reducing the symptoms of prostate inflammation and supporting overall prostate health.
Quercetin is utilized in the creation of anti-aging supplements, where it helps to reduce wrinkles, improve skin elasticity, and promote youthful-looking skin.

Quercetin is found in sports nutrition products, helping to reduce oxidative stress during exercise, enhance recovery, and improve endurance in athletes.
Quercetin is used in the development of natural antihistamines for individuals suffering from seasonal allergies, providing relief from common symptoms like nasal congestion, sneezing, and watery eyes.
Quercetin is a key ingredient in supplements designed to support healthy blood pressure, providing natural benefits for managing hypertension and improving cardiovascular health.



DESCRIPTION


Quercetin is a flavonoid found naturally in many fruits, vegetables, and grains, known for its powerful antioxidant, anti-inflammatory, and immune-boosting properties.
Quercetin is widely recognized for its ability to neutralize free radicals, reduce inflammation, and support cardiovascular health, making it a valuable ingredient in dietary supplements, skincare products, and wellness formulations.

Quercetin offers additional benefits such as supporting respiratory health, improving circulation, and promoting longevity by protecting cells from oxidative damage.
Quercetin is often incorporated into formulations designed to support immune function, improve allergy symptoms, and reduce inflammation, providing a comprehensive approach to wellness.
Quercetin is recognized for its ability to help prevent and manage chronic conditions such as heart disease, diabetes, and neurodegenerative disorders.

Quercetin is commonly used in both traditional and modern wellness formulations, providing a reliable solution for supporting the immune system, improving heart health, and promoting overall vitality.
Quercetin is valued for its ability to reduce oxidative stress, which plays a crucial role in preventing premature aging and promoting healthy skin and overall well-being.
Quercetin is a versatile ingredient that can be used in a variety of products, including supplements, capsules, creams, lotions, and skincare products.

Quercetin is an ideal choice for products targeting immune support, inflammation reduction, and cardiovascular health, providing natural and effective care for these concerns.
Quercetin is known for its compatibility with other antioxidant-rich and anti-inflammatory ingredients, making it easy to integrate into multi-functional formulations.
Quercetin is often chosen for formulations requiring a balance between immune support, inflammation relief, and heart health, ensuring comprehensive wellness benefits.

Quercetin enhances the overall effectiveness of wellness products by providing natural support for immune defense, inflammation reduction, and oxidative stress protection.
Quercetin is a reliable ingredient for creating products that offer noticeable improvements in immune function, allergy relief, and cardiovascular health.
Quercetin is an essential component in innovative wellness and beauty products known for their performance, safety, and ability to support immune health, skin protection, and overall vitality.



PROPERTIES


Chemical Formula: C15H10O7
Common Name: Quercetin
Molecular Structure:
Appearance: Yellow crystalline powder
Density: Approx. 1.8 g/cm³
Melting Point: 316 °C (601 °F)
Solubility: Soluble in ethanol, methanol; slightly soluble in water
Flash Point: Not applicable
Reactivity: Stable under normal conditions; no known reactivity issues
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store between 15-25°C in a cool, dry place
Vapor Pressure: Low



FIRST AID


Inhalation:
If Quercetin is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Wash the affected area with soap and water.
If skin irritation persists, seek medical attention.

Eye Contact:
In case of eye contact, flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
If Quercetin is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.



HANDLING AND STORAGE


Handling:
Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles if handling large quantities.
Use in a well-ventilated area to avoid inhalation of dust.

Ventilation:
Ensure adequate ventilation when handling large amounts of Quercetin to control airborne concentrations below occupational exposure limits.

Avoidance:
Avoid direct contact with eyes and prolonged skin contact.
Do not eat, drink, or smoke while handling Quercetin.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Contain spills to prevent further release and minimize exposure.
Absorb with inert material (e.g., sand, vermiculite) and collect for disposal.
Dispose of in accordance with local regulations.

Storage:
Store Quercetin in a cool, dry, well-ventilated area away from incompatible materials (see SDS for specific details).
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and ignition sources.

Handling Cautions:
Avoid inhalation of dust and direct contact with skin and eyes.
Use explosion-proof equipment in areas where dust or vapors may be present.

quercus infectoria fruit extract;oak fruit extract CAS NO:93165-57-2

ood Yellow 13; Sodium 2-(1,3-dioxoindan-2-yl)quinolinedisulfonate; 2-(1,3-Dioxoindan-2-yl) quinolinedisulfonic acid sodium salt; Sodium 2-(2-quinolyl) indan-1,3-dione-disulfonates CAS:8004-92-0

Quartemine; 1-Hexadecanaminium, N,N,N-trimethyl-, chloride cas no: 112-02-7

SYNONYMS Aciphex;2-[[[4-(3-methoxypropoxy) -3-methyl-2-pyridinyl]-methyl]sulfinyl] -1H–benzimidazole sodium salt; cas no:117976-89-3

Racemic acid is an organic acid found in many vegetables and fruits such as bananas, and grapes, but also in bananas, citrus, and tamarinds.
Racemic acid is a white, crystalline organic acid that occurs naturally in many fruits, most notably in grapes, but also in tamarinds, bananas, avocados and citrus.
Naturally occurring Racemic acid is a useful raw material in organic chemical synthesis.

CAS Number: 87-69-4
EC Number: 205-695-6
Molecular Formula: C4H6O6
Molecular Weight (g/mol): 150.09

Synonyms: (+)-L-Tartaric acid, (+)-Tartaric acid, 87-69-4, L-(+)-Tartaric acid, L-Tartaric acid, L(+)-Tartaric acid, tartaric acid, (2R,3R)-2,3-dihydroxysuccinic acid, (2R,3R)-2,3-dihydroxybutanedioic acid, (R,R)-Tartaric acid, Threaric acid, L-threaric acid, Dextrotartaric acid, Natural tartaric acid, Acidum tartaricum, DL-Tartaric acid, (2R,3R)-(+)-Tartaric acid, (+)-(R,R)-Tartaric acid, Tartaric acid, L-, Rechtsweinsaeure, Kyselina vinna, (2R,3R)-Tartaric acid, (R,R)-(+)-Tartaric acid, tartrate, Succinic acid, 2,3-dihydroxy, Weinsteinsaeure, L-2,3-Dihydroxybutanedioic acid, 133-37-9, (2R,3R)-rel-2,3-Dihydroxysuccinic acid, 1,2-Dihydroxyethane-1,2-dicarboxylic acid, EINECS 201-766-0, (+)-Weinsaeure, NSC 62778, FEMA No. 3044, INS NO.334, DTXSID8023632, UNII-W4888I119H, CHEBI:15671, Kyselina 2,3-dihydroxybutandiova, AI3-06298, Lamb protein (fungal), INS-334, (+/-)-Tartaric Acid, Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, (R,R)-tartrate, NSC-62778, W4888I119H, Tartaric acid (VAN), Kyselina vinna [Czech], DTXCID203632, E 334, E-334, RR-tartaric acid, (+)-(2R,3R)-Tartaric acid, Tartaric acid, L-(+)-, EC 201-766-0, TARTARIC ACID (L(+)-), Tartaric acid [USAN:JAN], Weinsaeure, BAROS COMPONENT TARTARIC ACID, L-2,3-DIHYDROXYSUCCINIC ACID, MFCD00064207, C4H6O6, L-tartarate, 4J4Z8788N8, 138508-61-9, (2R,3R)-2,3-Dihydroxybernsteinsaeure, TARTARIC ACID COMPONENT OF BAROS, Resolvable tartaric acid, d-alpha,beta-Dihydroxysuccinic acid, TARTARIC ACID (II), TARTARIC ACID [II], 144814-09-5, Kyselina 2,3-dihydroxybutandiova [Czech], REL-(2R,3R)-2,3-DIHYDROXYBUTANEDIOIC ACID, TARTARIC ACID (MART.), TARTARIC ACID [MART.], (1R,2R)-1,2-Dihydroxyethane-1,2-dicarboxylic acid, TARTARIC ACID (USP-RS), TARTARIC ACID [USP-RS], BUTANEDIOIC ACID, 2,3-DIHYDROXY-, (R-(R*,R*))-, Tartaric acid D,L, Butanedioic acid, 2,3-dihydroxy- (R-(R*,R*))-, TARTARIC ACID (EP MONOGRAPH), TARTARIC ACID [EP MONOGRAPH], Tartarate, DL-TARTARICACID, 132517-61-4, L(+) tartaric acid, (2RS,3RS)-Tartaric acid, 2,3-dihydroxy-succinic acid, Traubensaeure, Vogesensaeure, Weinsaure, acide tartrique, acido tartarico, tartaric-acid, para-Weinsaeure, L-Threaric aci, 4ebt, NSC 148314, NSC-148314, (r,r)-tartarate, (+)-tartarate, l(+)tartaric acid, Tartaric acid; L-(+)-Tartaric acid, Tartaric acid (TN), (+-)-Tartaric acid, Butanedioic acid, 2,3-dihydroxy-, (R*,R*)-, L-(+) tartaric acid, (2R,3R)-Tartarate, 1d5r, DL TARTARIC ACID, TARTARICUM ACIDUM, 2,3-dihydroxy-succinate, TARTARIC ACID,DL-, SCHEMBL5762, TARTARIC ACID, DL-, Tartaric acid (JP17/NF), TARTARIC ACID [FCC], TARTARIC ACID [JAN], d-a,b-Dihydroxysuccinic acid, TARTARIC ACID [INCI], MLS001336057, L-TARTARIC ACID [MI], TARTARIC ACID [VANDF], DL-TARTARIC ACID [MI], CCRIS 8978, L-(+)-Tartaric acid, ACS, TARTARIC ACID [WHO-DD], CHEMBL1236315, L-(+)-Tartaric acid, BioXtra, TARTARICUM ACIDUM [HPUS], UNII-4J4Z8788N8, (2R,3R)-2,3-tartaric acid, CHEBI:26849, HMS2270G22, Pharmakon1600-01300044, TARTARIC ACID, DL- [II], TARTARIC ACID, (+/-)-, TARTARIC ACID,DL- [VANDF], HY-Y0293, STR02377, TARTARIC ACID [ORANGE BOOK], EINECS 205-105-7, Tox21_300155, (2R,3R)-2,3-dihydroxysuccinicacid, NSC759609, s6233, AKOS016843282, L-(+)-Tartaric acid, >=99.5%, CS-W020107, DB09459, NSC-759609, (2R,3R)-2,3-dihydroxy-succinic acid, Butanedioic acid, 2,3-dihydroxy-; Butanedioic acid, 2,3-dihydroxy-, (R-(R*,R*))-, CAS-87-69-4, L-(+)-Tartaric acid, AR, >=99%, (R*,R*)-2,3-dihydroxybutanedioic acid, NCGC00247911-01, NCGC00254043-01, BP-31012, SMR000112492, SBI-0207063.P001, (2R,3R)-rel-2,3-dihydroxybutanedioic acid, NS00074184, T0025, EN300-72271, (R*,R*)-(+-)-2,3-dihydroxybutanedioic acid, C00898, D00103, D70248, L-(+)-Tartaric acid, >=99.7%, FCC, FG, L-(+)-Tartaric acid, ACS reagent, >=99.5%, L-(+)-Tartaric acid, BioUltra, >=99.5% (T), J-500964, J-520420, L-(+)-Tartaric acid, ReagentPlus(R), >=99.5%, L-(+)-Tartaric acid, SAJ first grade, >=99.5%, L-(+)-Tartaric acid, tested according to Ph.Eur., Butanedioic acid, 2,3-dihydroxy-, (R*,R*)-(+-)-, L-(+)-Tartaric acid, JIS special grade, >=99.5%, L-(+)-Tartaric acid, natural, >=99.7%, FCC, FG, L-(+)-Tartaric acid, p.a., ACS reagent, 99.0%, L-(+)-Tartaric acid, Vetec(TM) reagent grade, 99%, Q18226455, F8880-9012, Z1147451717, Butanedioic acid, 2,3-dihydroxy-, (theta,theta)-(+-)-, 000189E3-11D0-4B0A-8C7B-31E02A48A51F, L-(+)-Tartaric acid, puriss. p.a., ACS reagent, >=99.5%, L-(+)-Tartaric acid, certified reference material, TraceCERT(R), Tartaric acid, United States Pharmacopeia (USP) Reference Standard, L-(+)-Tartaric acid, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=99.5%, L-(+)-Tartaric acid, p.a., ACS reagent, reag. ISO, reag. Ph. Eur., 99.5%, Tartaric Acid, Pharmaceutical Secondary Standard; Certified Reference Material

Racemic acid is an organic acid found in many vegetables and fruits such as bananas, and grapes, but also in bananas, citrus, and tamarinds.
Racemic acid is also known as 2,3-dihydroxysuccinic acid or Tartaric acid.

Racemic acid is used to generate carbon dioxide.
Racemic acid is a diprotic aldaric acid which is crystalline white.
Baking powder is a mixture of Racemic acid with sodium bicarbonate.

Racemic acid is widely used in the field of pharmaceuticals.
High doses of Racemic acid can lead to paralysis or death.

Racemic acid is one of the least antimicrobial of the organic acids known to inactivate fewer microorganisms and inhibit less microbial growth in comparison with most other organic acids (including acetic, ascorbic, benzoic, citric, formic, fumaric, lactic, levulinic, malic, and propionic acids) in the published scientific literature.

Racemic acid is a tetraric acid, which is butanedioic acid substituted with hydroxy groups at the 2 and 3 positions.
Racemic acid has a role as a human xenobiotic metabolite and a plant metabolite.
Racemic acid is a conjugate acid of 3-carboxy-2,3-dihydroxypropanoate.

Racemic acid is a white, crystalline organic acid that occurs naturally in many fruits, most notably in grapes, but also in tamarinds, bananas, avocados and citrus.
Racemic acid salt, potassium bitartrate, commonly known as cream of tartar, develops naturally in the process of fermentation.

Racemic acid is commonly mixed with sodium bicarbonate and is sold as baking powder used as a leavening agent in food preparation.
Racemic acid itself is added to foods as an antioxidant E334 and to impart Racemic acid distinctive sour taste.

Racemic acid is an organic acid that naturally occurs in many fruits, most notably in grapes but also in bananas and citrus fruits.
Racemic acid is a white, crystalline solid which can easily be dissolved in water.

Approx. 50 % of the produced Racemic acid is subsequently used by the food and pharmaceutical industry, the other half is used in technical applications.
When added to food or beverage products, Racemic acid is denoted by E-number E 334.

Besides that, Racemic acid and its derivatives are often used in the field of pharmaceuticals or as a chelating agent in the farming and metal industry.

Naturally occurring Racemic acid is a useful raw material in organic chemical synthesis.
Racemic acid, an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics, and is a dihydroxyl derivative of succinic acid.

Racemic acid is a white crystalline organic acid that occurs naturally in many plants, most notably in grapes.
2,3-dihydroxybutanedioic is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics, and is a dihydroxyl derivative of succinic acid.

Racemic acid is a white crystalline organic acid that occurs naturally in many plants, most notably in grapes.
2,3-dihydroxybutanedioic is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics, and is a dihydroxyl derivative of succinic acid.

Racemic acid is a white crystalline diprotic organic acid.
Racemic acid occurs naturally in many plants, particularly in grapes, bananas, and tamarinds.
Racemic acid is also one of the main acids found in wine.

Racemic acid can be added to food when a sour taste is desired.
Racemic acid is also used as an antioxidant.

Salts of Racemic acid are known as tartarates.
Racemic acid is a dihydroxy derivative of succinic acid.

Racemic acid is found in cream of tartar and baking powder.
Racemic acid is used in silvering mirrors, tanning leather, and in Rochelle Salt.
In medical analysis, Racemic acid is used to make solutions for the determination of glucose.

Racemic acid is a naturally occurring dicarboxylic acid containing two stereocenters.
Racemic acid exists as a pair of enantiomers and an achiral meso compound.

Racemic acid is present in many fruits (fruit acid), and Racemic acid monopotassium salt is found as a deposit during the fermentation of grape juice.

Racemic acid is a historical compound, dating back to when Louis Pasteur separated Racemic acid into two enantiomers with a magnifying lens and a pair of tweezers more than 160 years ago.

Racemic acid has a stronger, sharper taste than citric acid.
Although Racemic acid is renowned for its natural occurrence in grapes, Racemic acid also occurs in apples, cherries, papaya, peach, pear, pineapple, strawberries, mangos, and citrus fruits.

Racemic acid is used preferentially in foods containing cranberries or grapes, notably wines, jellies, and confectioneries.
Commercially, Racemic acid is prepared from the waste products of the wine industry and is more expensive than most acidulants, including citric and malic acids.

Racemic acid is one of the least antimicrobial of the organic acids known to inactivate fewer microorganisms and inhibit less microbial growth in comparison with most other organic acids (including acetic, ascorbic, benzoic, citric, formic, fumaric, lactic, levulinic, malic, and propionic acids) in the published scientific literature.
Furthermore, when dissolved in hard water, undesirable insoluble precipitates of calcium tartrate can form.

Racemic acid is an abundant constituent of many fruits such as grapes and bananas and exhibits a slightly astringent and refreshing sour taste.
Racemic acid is one of the main acids found in wine.

Racemic acid is added to other foods to give a sour taste and is normally used with other acids such as citric acid and malic acid as an additive in soft drinks, candies, and so on.
Racemic acid is produced by acid hydrolysis of calcium tartrate, which is prepared from potassium tartrate obtained as a by-product during wine production.
Optically active Racemic acid is used for the chiral resolution of amines and also as an asymmetric catalyst.

Racemic acid is the most water-soluble of the solid acidulants.
Racemic acid contributes a strong tart taste that enhances fruit flavors, particularly grape and lime.

Racemic acid is often used as an acidulant in grape- and lime-flavored beverages, gelatin desserts, jams, jellies, and hard sour confectionery.

Racemic acid, a dicarboxylic acid, one of the most widely distributed of plant acids, with a number of food and industrial uses.
Along with several of Racemic acid salts, cream of tartar (potassium hydrogen tartrate) and Rochelle salt (potassium sodium tartrate), Racemic acid is obtained from by-products of wine fermentation.

Study of the crystallographic, chemical, and optical properties of the Racemic acids by French chemist and microbiologist Louis Pasteur laid the basis for modern ideas of stereoisomerism.

Racemic acid is widely used as an acidulant in carbonated drinks, effervescent tablets, gelatin desserts, and fruit jellies.
Racemic acid has many industrial applications—e.g., in cleaning and polishing metals, in calico printing, in wool dyeing, and in certain photographic printing and development processes.
Racemic acid is used in silvering mirrors, in processing cheese, and in compounding mild cathartics.

Racemic acid is incorporated into baking powders, hard candies, and taffies; and Racemic acid is employed in the cleaning of brass, the electrolytic tinning of iron and steel, and the coating of other metals with gold and silver.

Racemic acid is an organic acid.
Racemic acid is also known as 2,3-dihydroxysuccinic acid or Tartaric acid.
Racemic acid is in use to generate carbon dioxide.

Racemic acid is a diprotic aldaric acid.
Racemic acid is an alpha-hydroxy-carboxylic acid and is a dihydroxyl derivative of succinic acid.

Racemic acid is widely in use in the field of pharmaceuticals.
A High dose of Racemic acid can affect our body to a great extent.

Racemic acid is a white and crystalline that occurs naturally in many fruits and vegetables and most notably in grapes.
Racemic acid is also present in bananas, tamarinds, and citrus.

Racemic acid is commonly mixed with sodium bicarbonate and is sold as a baking powder that is in use as a leavening agent in food preparation.
The Racemic acid is added to foods being an antioxidant i.e., E334 and to impart Racemic acid distinctive sour taste.

Racemic acid, sometimes called Tartaric acid, is an organic compound that naturally occurs in plants, wine, and many fruits, such as grapes, tamarinds, citrus, and bananas.
The acid is available as a white solid that’s soluble in water.
Racemic acid salt, commonly referred to as cream of tartar, is created naturally through fermentation.

Racemic acid is made from potassium acid tartrate obtained from different by-products of the wine industry, such as lees, argol, and press cakes from fermented grape juice.
This dibasic acid is usually mixed with sodium bicarbonate and is available as baking powder commonly used as a food additive.

Uses of Racemic acid:
Racemic acid is Levo form of dextrorotatory Racemic acid.
Racemic acid is found throughout nature and classified as a fruit acid.

Racemic acid is used in soft drinks and foods, as an acidulant, complexing agent, pharmaceutic aid (buffering agent), in photography, tanning, ceramics, and to make tartrates.
Diethyl and dibutyl ester derivatives are commercially significant for use in lacquers and in textile printing.

Racemic acid is used as an intermediate, in construction and ceramics applications, in cleaning products, cosmetics/personal care products, and metal surface treatments (including galvanic and electroplating products).
Racemic acid is used as a flavoring agent, anticaking agent, drying agent, firming agent, humectant, leavening agent, and pH control agent for foods.

Racemic acid is used to improve the taste of oral medications.
Racemic acid is used to chelate metal ions such as magnesium and calcium.

Racemic acid is used in recipes as a leavening agent along with baking soda.
Racemic acid is used as an antioxidant.

Racemic acid is as one of the important acids in wine.
Racemic acid is used in foods to give a sour taste.

Racemic acid is sometimes used to induce vomiting.
Racemic acid is used to make silver mirrors.

In its ester form, Racemic acid is used in the dyeing of textiles.
Racemic acid is used in the tanning of leather.

Racemic acid is used in candies.
In its cream form, Racemic acid is used as a stabilizer in food.

Food industry:
Racemic acid is used as acidifier and natural preservative for marmalades, ice cream, jellies, juices, preserves, and beverages.
Racemic acid is used as effervescent for carbonated water.
Racemic acid is used as emulsifier and preservative in the bread-making industry and in the preparation of candies and sweets.

Oenology:
Racemic acid is used as an acidifier.
Racemic acid is used in musts and wines to prepare wines that are more balanced from the point of view of taste, the result being an increase in their degree of acidity and a decrease in their pH content.

Pharmaceuticals industry:
Racemic acid is used as an excipient for the preparation of effervescent tablets.

Construction industry:
Racemic acid is used in cement, plaster, and plaster of Paris to retard drying and facilitate the handling of these materials.

Cosmetics industry:
Racemic acid is used as a basic component of many natural body crèmes.

Chemical sector:
Racemic acid is used in galvanic baths.
Racemic acid is used in electronics industry.

Racemic acid is used as mordant in the textile industry.
Racemic acid is used as an anti-oxidant in industrial greases.

Industry Uses:
Processing aids not otherwise specified

Consumer Uses:
Processing aids not otherwise specified

Industrial Processes with risk of exposure:
Electroplating
Painting (Pigments, Binders, and Biocides)
Leather Tanning and Processing
Photographic Processing
Textiles (Printing, Dyeing, or Finishing)

Usage Areas of Racemic acid:
Racemic acid, this crystalline acid, is commonly seen in plants and fruits.
The chemical formula of Racemic acid, an organic acid, is C4H6O6 and its density is 1.788g/cm.

Racemic acid is used in different branches of industry, especially industry.
Racemic acid is generally preferred for the fermentation of wine and is formed as a byproduct of potassium during fermentation.

Racemic acid is frequently used in wool dyeing, polishing, gelatin, desserts and sodas.
Racemic acid, which is mostly found in grape fruits, also occurs in some fruits other than grapes.

Racemic acid, which is formed from the mixture of raceme, is called levo.
Racemic acids are among the water-soluble dicarboxylic acids.

Racemic acid is used to give a sour taste to foods.
Racemic acid, E334, is a good antioxidant.

The most common use of Racemic acid is in soda production.
Racemic acid, which is used to flavor soda, is an indispensable component of soda.

Racemic acid is preferred for dyeing wool.
Racemic acid can be used for polishing, polishing and cleaning metals.

Racemic acid is used to release carbon dioxide in bakery products.
Racemic acid, an indispensable ingredient in gelatin desserts, is generally preferred as a thickener in products such as meringue, Turkish delight and whipped cream.

The form of Racemic acid obtained from grapes is generally preferred in pastry.
Racemic acid can be preferred over baking powder for rising cakes.

Racemic acid, which is frequently found in fruits and has a tart and strong taste, is preferred for winemaking and fermentation of wine.
Racemic acid is used in making marmalade and jams.

Applications of Racemic acid:
Racemic acid and its derivatives have a plethora of uses in the field of pharmaceuticals.
For example, Racemic acid has been used in the production of effervescent salts, in combination with citric acid, to improve the taste of oral medications.

Racemic acid also has several applications for industrial use.

The acid has been observed to chelate metal ions such as calcium and magnesium.
Therefore, the acid has served in the farming and metal industries as a chelating agent for complexing micronutrients in soil fertilizer and for cleaning metal surfaces consisting of aluminium, copper, iron, and alloys of these metals, respectively.

Racemic acid is used in fuels and fuel additives, laboratory chemicals, lubricants and lubricant additives, coating agents and surface treatment agents.
Racemic acid is used in processing aids and petroleum production specific processing aids.

Racemic acid is used in ink, toner and coloring products, laboratory use, lubricants and greases.
Racemic acid is found in cream of tartar, which is used in making candies and frostings for cakes.

Racemic acid is also used in baking powder where Racemic acid serves as the source of acid that reacts with sodium bicarbonate (baking soda).
This reaction produces carbon dioxide gas and lets products “rise,” but Racemic acid does so without the “yeast” taste that can result from using active yeast cultures as a source of the carbon dioxide gas.

Racemic acid is used in silvering mirrors, tanning leather, and in the making of Rochelle Salt, which is sometimes used as a laxative.
Blue prints are made with ferric tartarte as the source of the blue ink.

In medical analysis, Racemic acid is used to make solutions for the determination of glucose.
Common esters of Racemic acid are diethyl tartarate and dibutyl tartrate.
Both are made by reacting Racemic acid with the appropriate alcohol, ethanol or n-butanol.

Racemic acid in wine:
Racemic acid may be most immediately recognizable to wine drinkers as the source of "wine diamonds", the small potassium bitartrate crystals that sometimes form spontaneously on the cork or bottom of the bottle.

Racemic acid plays an important role chemically, lowering the pH of fermenting "must" to a level where many undesirable spoilage bacteria cannot live, and acting as a preservative after fermentation.
In the mouth, Racemic acid provides some of the tartness in the wine, although citric and malic acids also play a role.

Racemic acid in fruits:
Grapes and tamarinds have the highest levels of Racemic acid concentration.
Other fruits with Racemic acid are bananas, avocados, prickly pear fruit, apples, cherries, papayas, peaches, pears, pineapples, strawberries, mangoes and citrus fruits.

Results from a study showed that in citrus (oranges, lemons and mandarins), fruits produced in organic farming contain higher levels of Racemic acid than fruits produced in conventional agriculture.

Trace amounts of Racemic acid have been found in cranberries and other berries.
Racemic acid is also present in the leaves and pods of Pelargonium plants and beans.

Retarding Agent:
Racemic acid is widely used as a retarding agent in oilfield applications as well as in cementitious-based systems.
Racemic acid works by slowing the setting of cement by impeding certain reactions during the hydration of the cement process.
Racemic acid retards various steps, including ettringite formation and C3A hydration.

Food Additive:
Racemic acid also has many uses in the food industry.
As an acidulant, Racemic acid offers a pleasant sour taste and gives food a sharp flavor.

Racemic acid also serves as a preservative food agent and can help set gels.
Racemic acid is usually added to most products, including carbonated beverages, gelatin, fruit jellies, and effervescent tablets.
This acid is also used as an ingredient in candy and various brands of baking powders and leavening systems to make goods rise.

Industrial Applications:
Racemic acid has many industrial applications.
Racemic acid’s used in gold and silver plating, making blue ink for blueprints, tanning leather, and cleaning and polishing metals.
Racemic acid’s also one of the ingredients in Rochelle Salt, which is luxuriant and reacts with silver nitrate to form the silvering in mirrors.

Commercial Application:
The by-products obtained from the fermentation of wine during the production of Racemic acid are heated with calcium hydroxide.
This causes calcium tartrate to develop a residue, which is further treated with sulfuric acid to form a mixture of Racemic acid and calcium sulfate.
Once the mixture is separated, Racemic acid is purified and used for commercial production.

Other Racemic acid uses include pharmaceutical applications to produce effervescent salt that helps enhance the taste of oral medications.
Racemic acid’s also used in the metals and farming industry as a chelating agent for cleaning metal surfaces and adding nutrients to the soil.

Derivatives of Racemic acid:

Important derivatives of Racemic acid include:
Sodium ammonium tartrate, the first material separated into Racemic acid enantiomers
Cream of tartar (potassium bitartrate), used in cooking
Rochelle salt (potassium sodium tartrate), which has unusual optical properties
Tartar emetic (antimony potassium tartrate), a resolving agent.
Diisopropyl tartrate is used as a co-catalyst in asymmetric synthesis.

Racemic acid is a muscle toxin, which works by inhibiting the production of malic acid, and in high doses causes paralysis and death.
As a food additive, Racemic acid is used as an antioxidant with E number E334; Racemic acids are other additives serving as antioxidants or emulsifiers.

Production of Racemic acid:
Racemic acid is industrially produced in the largest amounts.
Racemic acid is obtained from lees, a solid byproduct of fermentations.
The former byproducts mostly consist of potassium bitartrate (KHC4H4O6).

This potassium salt is converted to calcium tartrate (CaC4H4O6) upon treatment with calcium hydroxide "milk of lime" (Ca(OH)2):
KH(C4H4O6) + Ca(OH)2 -> Ca(C4H4O6) + KOH + H2O

In practice, higher yields of calcium tartrate are obtained with the addition of calcium chloride.

Calcium tartrate is then converted to Racemic acid by treating the salt with aqueous sulfuric acid:
Ca(C4H4O6) + H2SO4 -> H2(C4H4O6) + CaSO4

Racemic Racemic acid:
Racemic Racemic acid can be prepared in a multistep reaction from maleic acid.

In the first step, the maleic acid is epoxidized by hydrogen peroxide using potassium tungstate as a catalyst.
HO2CC2H2CO2H + H2O2 → OC2H2(CO2H) 2

In the next step, the epoxide is hydrolyzed.
OC2H2(CO2H)2 + H2O → (HOCH)2(CO2H)2

meso-Racemic acid:
A mixture of racemic acid and meso-Tartaric acid is formed when dextro-Racemic acid is heated in water at 165 °C for about 2 days.

meso-Racemic acid can also be prepared from dibromosuccinic acid using silver hydroxide:
HO2CCHBrCHBrCO2H + 2 AgOH → HO2CCH(OH)CH(OH)CO2H + 2 AgBr

meso-Tartaric acid can be separated from residual racemic acid by crystallization, the racemate being less soluble.

General Manufacturing Information of Racemic acid:

Industry Processing Sectors:
Computer and Electronic Product Manufacturing
Construction
Not Known or Reasonably Ascertainable

Stereochemistry of Racemic acid:
Naturally occurring form of the acid is dextro Racemic acid.
Because Racemic acid is available naturally, Racemic acid is cheaper than its enantiomer and the meso isomer.

Dextro and levo form monoclinic sphenoidal crystals and orthorhombic crystals.
Racemic Racemic acid forms monoclinic and triclinic crystals (space group P1).

Anhydrous meso Racemic acid form two anhydrous polymorphs: triclinic and orthorhombic.
Monohydrated meso Racemic acid crystallizes as monoclinic and triclinic polymorphys depending on the temperature at which crystallization from aqueous solution occurs.
Racemic acid in Fehling's solution binds to copper(II) ions, preventing the formation of insoluble hydroxide salts.

History of Racemic acid:
Racemic acid has been known to winemakers for centuries.
However, the chemical process for extraction was developed in 1769 by the Swedish chemist Carl Wilhelm Scheele.

Racemic acid played an important role in the discovery of chemical chirality.
This property of Racemic acid was first observed in 1832 by Jean Baptiste Biot, who observed Racemic acid ability to rotate polarized light.

Louis Pasteur continued this research in 1847 by investigating the shapes of sodium ammonium tartrate crystals, which he found to be chiral.
By manually sorting the differently shaped crystals, Pasteur was the first to produce a pure sample of levoRacemic acid.

Pharmacology and Biochemistry of Racemic acid:

Pharmacodynamics:
Racemic acid is used to generate carbon dioxide through interaction with sodium bicarbonate following oral administration.
Carbon dioxide extends the stomach and provides a negative contrast medium during double contrast radiography.
In high doses, this agent acts as a muscle toxin by inhibiting the production of malic acid, which could cause paralysis and maybe death.

Route of Elimination:
Only about 15-20% of consumed Racemic acid is secreted in the urine unchanged.

Metabolism / Metabolites:
Most tartarate that is consumed by humans is metabolized by bacteria in the gastrointestinal tract, primarily in the large instestine.

Human Metabolite Information of Racemic acid:

Tissue Locations:
Adipose Tissue
Platelet
Prostate

Cellular Locations:
Cytoplasm

Reactivity of Racemic acid:
Racemic acid, can participate in several reactions.

As shown the reaction scheme below, dihydroxymaleic acid is produced upon treatment of Racemic acid with hydrogen peroxide in the presence of a ferrous salt.
HO2CCH(OH)CH(OH)CO2H + H2O2 → HO2CC(OH)C(OH)CO2H + 2 H2O

Dihydroxymaleic acid can then be oxidized to Racemic acid with nitric acid.

Accidental Release Measures of Racemic acid:

Spillage Disposal:

Personal protection:
Particulate filter respirator adapted to the airborne concentration of Racemic acid.
Sweep spilled substance into covered containers.

If appropriate, moisten first to prevent dusting.
Store and dispose of according to local regulations.

Identifiers of Racemic acid:
CAS Number:
R,R-isomer: 87-69-4
S,S-isomer: 147-71-7
racemic: 133-37-9
meso-isomer: 147-73-9
ChEBI: CHEBI:15674

ChEMBL:
ChEMBL333714
ChEMBL1200861

ChemSpider: 852
DrugBank: DB01694
ECHA InfoCard: 100.121.903
E number: E334 (antioxidants, ...)
KEGG: C00898
MeSH: tartaric+acid
PubChem CID: 875 unspecified isomer
UNII: W4888I119H
CompTox Dashboard (EPA): DTXSID5046986
InChI: InChI=1S/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)
Key: FEWJPZIEWOKRBE-UHFFFAOYSA-N
InChI=1/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)
Key: FEWJPZIEWOKRBE-UHFFFAOYAZ
SMILES: O=C(O)C(O)C(O)C(=O)O

CAS number: 147-71-7
EC number: 205-695-6
Hill Formula: C₄H₆O₆
Chemical formula: HOOCCH(OH)CH(OH)COOH
Molar Mass: 150.09 g/mol
HS Code: 2918 12 00

CAS: 87-69-4
Molecular Formula: C4H6O6
Molecular Weight (g/mol): 150.09
MDL Number: MFCD00064207
InChI Key: FEWJPZIEWOKRBE-UHFFFAOYNA-N
PubChem CID: 444305
ChEBI: CHEBI:15671
SMILES: OC(C(O)C(O)=O)C(O)=O

Properties of Racemic acid:
Chemical formula:
C4H6O6 (basic formula)
HO2CCH(OH)CH(OH)CO2H (structural formula)

Molar mass: 150.087 g/mol
Appearance: White powder

Density:
1.737 g/cm3 (R,R- and S,S-)
1.79 g/cm3 (racemate)
1.886 g/cm3 (meso)

Melting point:
169, 172 °C (R,R- and S,S-)
206 °C (racemate)
165-6 °C (meso)

Solubility in water:
1.33 kg/L (L or D-tartaric)
0.21 kg/L (DL, racemic)
1.25 kg/L ("meso")

Acidity (pKa): L(+) 25 °C: pKa1= 2.89, pKa2= 4.40
meso 25 °C: pKa1= 3.22, pKa2= 4.85
Conjugate base: Bitartrate
Magnetic susceptibility (χ): −67.5·10−6 cm3/mol

Density: 1.8 g/cm3 (20 °C)
Flash point: 210 °C
Ignition temperature: 425 °C
Melting Point: 172 - 174 °C
Solubility: 1394 g/l

grade: ACS reagent
Quality Level: 200
vapor density: 5.18 (vs air)
Assay: ≥99.5%

form:
crystalline powder
crystals

optical activity: [α]20/D +12.4°, c = 20 in H2O
optical purity: ee: 99% (GLC)
autoignition temp.: 797 °F

impurities:
≤0.002% S compounds
≤0.005% insolubles

ign. residue: ≤0.02%
mp: 170-172 °C (lit.)

anion traces:
chloride (Cl-): ≤0.001%
oxalate (C2O42-): passes test
phosphate (PO43-): ≤0.001%

cation traces:
Fe: ≤5 ppm
heavy metals (as Pb): ≤5 ppm

SMILES string: O[C@H]([C@@H](O)C(O)=O)C(O)=O
InChI: 1S/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)/t1-,2-/m1/s1
InChI key: FEWJPZIEWOKRBE-JCYAYHJZSA-N

Molecular Weight: 150.09 g/mol
XLogP3-AA: -1.9
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 3
Exact Mass: 150.01643791 g/mol
Monoisotopic Mass: 150.01643791 g/mol
Topological Polar Surface Area: 115Ų
Heavy Atom Count: 10
Complexity: 134
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 2
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Racemic acid:
Assay (acidimetric): ≥ 99.0 %
Melting range (lower value): ≥ 166 °C
Melting range (upper value): ≤ 169 °C
Spec. rotation [α²0/D (c=10 in water): -14.0 - -12.0 °
Identity (IR): passes test

Melting Point: 168.0°C to 172.0°C
Color: White or Colorless
Assay Percent Range: 99+%
Linear Formula: HO2CCH(OH)CH(OH)CO2H
Solubility Information: Solubility in water: 1390g/L (20°C).
Other solubilities: soluble in methanol, ethanol, propanol and, glycerol, 4g/L ether, insoluble in chloroform
IUPAC Name: Racemic acid
Formula Weight: 150.09
Percent Purity: ≥99%
Quantity: 500 g
Flash Point: 210°C
Infrared Spectrum: Authentic
Loss on Drying: 0.5% (1g, 105°C) max.
Packaging: Plastic bottle
Physical Form: Crystals or Crystalline Powder
Chemical Name or Material: L(+)-Tartaric acid

Related compounds of Racemic acid:
2,3-Butanediol
Cichoric acid

Other cations:
Monosodium tartrate
Disodium tartrate
Monopotassium tartrate
Dipotassium tartrate

Related carboxylic acids:
Butyric acid
Succinic acid
Dimercaptosuccinic acid
Malic acid
Maleic acid
Fumaric acid

Names of Racemic acid:

Preferred IUPAC name:
Racemic acid

Other names:
Tartaric acid
2,3-Dihydroxysuccinic acid
Threaric acid
Tartaric acid
Uvic acid
Paratartaric acid
Winestone

Radia 7513 is the ester obtained from the reaction of tridecyl alcohol combined with stearic acid.


CAS Number: 95912-88-2
EC Number: 306-084-8
Chemical name : isotridecyl stearate
chemical name : Fatty acids, C16-18, isotridecyl esters


In raw material form, Radia 7513 is described as a clear oily liquid that may have a light-yellow hue.
Radia 7513 has been deemed safe by the Cosmetic Ingredient Review Expert Panel.


Radia 7513 contains tridecyl alcohol (1-tridecanol) as alcoholic component.
Stearates are salts or esters of stearic acid (octadecanoic acid).
Radia 7513 is the ester obtained from the reaction of tridecyl alcohol combined with stearic acid.



USES and APPLICATIONS of RADIA 7513:
Radia 7513 is used Ingredients for skincare.
Radia 7513 or 11-methyldodecyl octadecanoate or Octadecanoic acid is isotridecyl ester.
Radia 7513 is used in Skin care products, Raw material for spin finishes and oiling agent for textile, Rubber processing agent, Plastic lubricant, Paint & Ink additive.


Radia 7513 is ester used as a processing additive in polymers.
Radia 7513 is used raw material for spin finishes and oiling agent for textile, Rubber processing agent, Plastic lubricant, Paint & Ink additive.
Radia 7513’s used in cosmetics as a texture-enhancer/thickening agent and emollient and may be animal-derived or synthetic (Paula’s Choice uses the latter).



RADIA 7513 AT A GLANCE:
*The ester obtained from the reaction of tridecyl alcohol combined with stearic acid
*Works as a texture-enhancer/thickening agent and skin-softening emollient
*Touted for its quick absorption and velvety after feel
*Described as a clear oily liquid in raw material form



FUNCTIONS OF RADIA 7513 IN COSMETIC PRODUCTS:
*SKIN CONDITIONING
Radia 7513 maintains the skin in good condition



PHYSICAL and CHEMICAL PROPERTIES of RADIA 7513:
Appearance : light yellow oily liquid
acid value : max 1 mg KOH/g
other : iodine value: max 1 gI2/100 g
viscosity at 40 °C: 14-18 mm²/s
Moisture : max 0,1%
Density : 0,85:
Flashpoint: >210 °C
Molecular Weight: 466.8 g/mol
XLogP3-AA: 14.4
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 28
Exact Mass: 466.47498122 g/mol
Monoisotopic Mass: 466.47498122 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Count: 33

Formal Charge: 0
Complexity: 377
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
LogP: 14.386 (est)
EWG's Food Scores: 1
Appearance: Clear colorless to light yellow liquid.
Purity: 96% minimum.
Boiling point: 490C.
Flash point: 255C.
Relative density: about 0.9
Acid value: 1.0 maximum.
Saponification value: 120 – 130
Hydroxyl value: 3 maximum.
Color: 50 apha maximum.
Moisture: 0.1% maximum.



FIRST AID MEASURES of RADIA 7513:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of RADIA 7513:
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of RADIA 7513:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of RADIA 7513:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
*Body Protection:
Impervious clothing.
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
No special environmental precautions required



HANDLING and STORAGE of RADIA 7513:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of RADIA 7513:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
Fettsuren, C16-18-, Isotridecylester
Fatty acids, C16-18, isotridecyl esters
Fatty acids, C16-18, isotridecyl esters
Isotridecyl stearate
31565-37-4
11-methyldodecyl octadecanoate
Octadecanoic acid, isotridecyl ester
Octadecanoic acid,isotridecyl ester
J8793TKA30
Stearic acid, isotridecyl ester
EINECS 250-703-3
UNII-J8793TKA30
EXCEPARL TD-S
SCHEMBL2699239
ISOTRIDECYL STEARATE [INCI]
W-110802
Q27281337
Isotridecylstearat
isotridecyl stearate
11-methyldodecyl octadecanoate
Stearic acid, isotridecyl ester
Octadecanoic acid, isotridecyl ester

RADIACID 0907 is derived from 100% vegetable origin.
Due to their branched structure the RADIACID 0907 has a characteristic emollient feel
RADIACID 0907 has a non-greasy feel


CAS NUMBER: 2724-58-5

EC NUMBER: 250-178-0

MOLECULAR FORMULA: C18H36O2

MOLECULAR WEIGHT: 284.5 g/mol

IUPAC NAME: 16-methylheptadecanoic acid


RADIACID 0907 has a highly substantive lipid film
Soft skin feel and leaves a glossy appearance to the skin

RADIACID 0907 is used in colour cosmetics, deodorants and personal care products, where it provides film-forming and spreading functions.
RADIACID 0907 is an exceptionally good emollient with a pleasant feel, and is used widely in skin and body care products.

RADIACID 0907 is used in the following products:
-washing & cleaning products
-adhesives and sealants
-fuels
-lubricants and greases
-coating products
-fertilisers

RADIACID 0907 is used in biocides (e.g. disinfectants, pest control products)
RADIACID 0907 is also used in pH regulators and water treatment products

RADIACID 0907 can be used in laboratory chemicals, plant protection products, water softeners and water treatment chemicals.
RADIACID 0907 is used in formulation of mixtures
RADIACID 0907 is used for the manufacture of chemicals.

RADIACID 0907 is prepared from soybean oil and tallow.
RADIACID 0907 comes as white to pale yellow, clear oily liquid.

RADIACID 0907 is liquid at room temperature.
RADIACID 0907 is chemically, a carboxyl group attached to alkyl chain, methylated, branched at various carbons makes it much more stable compared to other linear chain fatty acids, including oxidation potential.

RADIACID 0907 is a yellow solution and its chemical formula is C18H36O2.
RADIACID 0907 is a saturated carbon solution.
RADIACID 0907 is found naturally in meat products and vegetable oils.

RADIACID 0907 can be used as a lubricant, that can improve flow of a powder mixture.
RADIACID 0907 has excellent spreadability without oiliness

RADIACID 0907 is a fatty acid molecule with an 18-carbon atom chain backbone.
RADIACID 0907 is an isomer of stearic acid, meaning that they both have a chemical formula of C18H36O2, but differ in the arrangement of their atoms.

RADIACID 0907 is used in personal care products
RADIACID 0907 is also used in cosmetic industry

RADIACID 0907 has lubricating or adhesive properties
RADIACID 0907 is also used in paper products.

While stearic acid has a linear carbon chain with 18 carbon atoms, isosteric acid as a carbon chain with 17 atoms and a single carbon branch at the 16th carbon atom. Its chemical structure can be represented as (CH3)2CH(CH2)14CO2H.
RADIACID 0907 is found naturally in meat products and vegetable oils.

RADIACID 0907 has a wide range of industrial uses.
RADIACID 0907 is mainly used as an additive in adhesives or lubricants for both paints and personal care products.

RADIACID 0907 is an important raw material in the preparation of speciality surfactants for consumer care products.
RADIACID 0907 (RADIACID 0907) is used in the synthesis of methyl-branched poly(hydroxyalkanoate)s, biosurfactants and silver nanoparticles

RADIACID 0907 is a lightly-branched, liquid fatty acid produced by the reaction of oleic acid with a natural mineral catalyst
There is no chemical addition in this reaction, RADIACID 0907 is based 100% on the parent oil or fat.

RADIACID 0907 is used in applications which require a liquid fatty acid with exceptional stability: thermal stability in the case of a lubricant, odour stability for a cosmetic formulation, and oxidation stability for products with long shelf-life requirements.
The branching structure of RADIACID 0907 also enhances its dispersing power

RADIACID 0907 has high performance lubricants with excellent cold stability
RADIACID 0907 is used in metal rolling fluids

Being a fatty acid, RADIACID 0907 is also amphiphilic, meaning it is a molecule with a hydrophobic end and a hydrophilic end.
As such, RADIACID 0907 can have favorable interactions with both polar and non-polar molecules, enabling it to act as a surfactant.

RADIACID 0907 is also soluble in many oils, which allows it to be used as an emulsifier or dispersant.
With this set of properties, RADIACID 0907 is a useful additive in a variety of applications, including:

-Adhesives
-Coatings and paints
-Finishing agents
-Lubricants
-Sealants
-Solvents
-Surfactants
-Viscosity adjusters

RADIACID 0907 is used as a cosmetic esters
RADIACID 0907 is used in manufacturing of soaps

RADIACID 0907 is a long-chain fatty acid
RADIACID 0907 is functionally related to a heptadecanoic acid.
RADIACID 0907 is a natural product found in Aristolochia grandiflora, Streptomyces, and other organisms with data available.


PHYSICAL PROPERTIES:

-Molecular Weight: 284.5 g/mol

-XLogP3: 7.2

-Exact Mass: 284.271530387 g/mol

-Monoisotopic Mass: 284.271530387 g/mol

-Topological Polar Surface Area: 37.3Ų

-Physical Description: Colorless Liquid

-Boiling Point: 400 °C

-Melting Point: 69.5 °C

-Solubility: 0.007116 mg/L

-LogP: 7.674

-Refractive Index: 1.4440 (estimate)

-Storage Temperature: 2-8°C

-pka: 4.78


RADIACID 0907 is used in cosmetic and industrial applications for the stabilisation of pigments and mineral particles in oils and solvents.
RADIACID 0907 is used for a cosmetic formulations

RADIACID 0907 can be used in industrial applications for the stabilisation of pigments mineral particles in oils and solvents
RADIACID 0907 differs from other C18 fatty acids of the same category in a number of ways.


CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 1

-Hydrogen Bond Acceptor Count: 2

-Rotatable Bond Count: 15

-Heavy Atom Count: 20

-Formal Charge: 0

-Complexity: 212

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 1

-Compound Is Canonicalized: Yes


RADIACID 0907 is also used in paper products
RADIACID 0907 is a methyl-branched fatty acid that is heptadecanoic acid (margaric acid) substituted by a methyl group at position 16.
RADIACID 0907 is used in the synthesis of methyl-branched poly(hydroxyalkanoate)s, biosurfactants and silver nanoparticles.

RADIACID 0907 is a lightly-branched, liquid fatty acid produced by the reaction of oleic acid with a natural mineral catalyst - there is no chemical addition in this reaction, RADIACID 0907 is based 100% on the parent oil or fat.
RADIACID 0907's is a light yellow liquid

APPLICATIONS:
Synthetic lubricants – RADIACID 0907 has good thermal and oxidative stability

Lubricant additives – RADIACID 0907 is derivatized to isostearyl amide to provide boundary lubrication and detergency

Coatings – RADIACID 0907 imparts flexibility and durability properties to industrial coatings

Metalworking – RADIACID 0907 has good surface activity for protective coatings and thermal stability for rolling and stamping

Personal care products – RADIACID 0907 is derivatized to isostearyl alcohol to impart feel and texture to creams and lotions.

RADIACID 0907 is used in personal care formulations for its function as both an emollient and co-emulsifier.
RADIACID 0907 is a synthetically created fatty acid most often used as a binder in skin and beauty products, although it is also seen in products as a surfactant and emulsifier.

RADIACID 0907 is a unique fatty acid.
RADIACID 0907 combines the best properties of stearic acid with the best properties of oleic acid.

RADIACID 0907 is an 18-carbon branched-chain fatty acid naturally found in plants and animals.
However, RADIACID 0907's a blend of many octadecanoic acids, found in vegetables and animals fat.

RADIACID 0907 is used to thicken most formulas as a binder and emulsifier.
RADIACID 0907 is a lightly-branched, liquid fatty acid produced by the reaction of oleic acid with a natural mineral catalyst.
RADIACID 0907 serves as a smooth, dry feeling emollient able to assist the skin in replenishing its natural moisture.

RADIACID 0907 can be easily used in a cosmetic which not only moisturizes skin but also does not leave any oily feel.
However, in cosmetic formulation RADIACID 0907 is used as a binder to form cake-like compact powder or eye shadow.
RADIACID 0907 is also used in cleansing and emulsifying agent, because of presence of both ionic and nonionic groups.

RADIACID 0907 is used in varieties of cosmetic and personal care products.
RADIACID 0907 is a synthetically created fatty acid
RADIACID 0907 is used as a binder in skin and beauty products

RADIACID 0907 is a clear, oily liquid that is used in a wide variety of cosmetics and personal care products.
RADIACID 0907 (16-Methylheptadecanoic acid) is used in the synthesis of methyl-branched poly(hydroxyalkanoate)s, biosurfactants and silver nanoparticles.
RADIACID 0907 is a fatty acid that is used as an emollient in pharmaceutical preparations.
RADIACID 0907 has been shown to have skin-moisturizing and anti-inflammatory properties, which are due to its ability to inhibit the activity of phospholipase A2.

RADIACID 0907 is a fatty acid molecule with an 18-carbon atom chain backbone.
RADIACID 0907 is an isomer of stearic acid
RADIACID 0907's chemical formula is C18H36O2

RADIACID 0907 is a liquid fatty acid created from oleic acid.
RADIACID 0907's claimed to have great odour, thermal and oxidation stability and is great for the stabilization of pigments and mineral particles in oils and solvents.

RADIACID 0907's quite popular in foundations.
RADIACID 0907 is our unique, highly branched, saturated fatty acid.

RADIACID 0907 has some features that are transparent and odorless, unlike straight chain fatty acids.
Additionally, RADIACID 0907 has excellent heat stability, oxidation resistance, pigment dispensing ability, defoaming property and is compatible with various organic solvents.

RADIACID 0907 is a fatty acid which contains 18-carbon atom chain.
The IUPAC name of RADIACID 0907 is octadecanoic acid.

RADIACID 0907 is a yellow solution and its chemical formula is C18H36O2.
RADIACID 0907 is a saturated carbon solution.

RADIACID 0907 is found naturally in meat products and vegetable oils.
The molecular mass of RADIACID 0907 is 284.48 g/mol.

RADIACID 0907 is soluble in many oils
RADIACID 0907 is used as an emulsifier or dispersant.

RADIACID 0907 is derived from renewable sources, offering unique characteristics such as high oxidation resistance and excellent cold temperature properties.
Applications include additives or base stock for the fuel and lubricants industry and emollients for personal care.

RADIACID 0907 is a high quality 16-Methylheptadecanoic acid used in synthesis.
This product has been used as molecular tool for various biochemical applications.
RADIACID 0907 has also been used in a wide array of other chemical and immunological applications.


SYNONYMS:

RADIACID 0907
Radiacid 0907
jaric I-18CG
jaric I-18IG
jaric I-18LG
liponate ISA
ISOOCTADECANOIC ACID
isostearic
16-METHYLHEPTADECANOIC ACID
Isostearinsure
ISOSTEARIC ACID
16-methyl-heptadecanoicaci
Heptadedecanoicacid,16-Methyl
ISOSTEARIC ACID MIXED ISOMERS
Heptadecanoic acid, 16-methyl-
heptadecanoic acid, 16-methyl-
jaric I-18CG
jaric I-18IG
jaric I-18LG
liponate ISA
16-methyl heptadecanoic acid
16-methyl margaric acid
16-methylheptadecanoic acid
isooctadecanoic acid
prisorine 3505
prisorine 3515
isostearicacid
ISOSTEARIC ACID
Isooctadecanoic acid
16-METHYLHEPTADECANOIC ACID
2724-58-5
30399-84-9
Prisorine 3509
Heptadecanoic acid, 16-methyl-
16-methyl margaric acid
16-methyl-heptadecanoic acid
LZM5XA0ILL
CHEBI:84896
(+)-Isostearic acid
UNII-LZM5XA0ILL
EINECS 220-336-3
16-methylmargaric acid
EMERSOL 873
SCHEMBL15489
CHEMBL1865303
DTXSID1040790
16-METHYLHEPTADECANOICACID
LMFA01020014
HY-W127433
NCGC00164392-01
NCGC00164392-02
NCGC00255115-01
AS-57253
CAS-30399-84-9
CS-0185665
Isostearic acid
16-Methylheptadecanoic acid
220-336-3
250-178-0
2724-58-5
30399-84-9
Heptadecanoic acid, 16-methyl-
Isooctadecanoic acid
MFCD00044082
MI3875000
X33R8U0062
(+)-isostearic acid
16-methyl margaric acid
16-methyl-heptadecanoic acid
16-methylmargaric acid
2-methyl-heptadecanoic acid
2-Methylheptadecanoic acid
Heptadecanoic acid, 2-methyl-
λ-Isostearic acid
Isostearic acid
16-Methylheptadecanoic acid
220-336-3
250-178-0
2724-58-5
30399-84-9
Acide 16-méthylheptadécanoïque
Heptadecanoic acid, 16-methyl-
Isooctadecanoic acid
MI3875000
X33R8U0062
(+)-isostearic acid
16-methyl margaric acid
16-methyl-heptadecanoic acid
16-methylmargaric acid
2-methyl-heptadecanoic acid
2-Methylheptadecanoic acid
Heptadecanoic acid, 2-methyl-
λ-Isostearic acid

DESCRIPTION:

Radiasurf 7403 acts as a non-ionic surfactant and emulsifier for o/w emulsions.
Radiasurf 7403 is non-toxic, non-irritating, non-exhaustive, fully biodegradable and environment friendly in nature.
Radiasurf 7403 is an electrolyte tolerant, high molecular weight member and is used as viscosity builder in detergent systems.



CAS NUMBER: 9004-96-0

EC NUMBER: 500-015-7

MOLECULAR FORMULA: C18H33O2.(C2H4O)n.H



DESCRIPTION:

Radiasurf 7403 can also be used for melting point control and is suitable for use in antiperspirants.
Radiasurf 7403 finds application in formulating facial-, body-, baby- and sun-care products.
Radiasurf 7403 is an ingredient commonly used in cosmetic and personal care products.

Radiasurf 7403 is a polyethylene glycol (PEG) derivative of oleic acid, which is a naturally occurring fatty acid found in various vegetable oils.
Radiasurf 7403 is created by reacting oleic acid with ethylene oxide, resulting in a compound that has emulsifying and surfactant properties.
In cosmetic formulations, Radiasurf 7403 functions as an emulsifier, helping to mix oil and water-based ingredients together.

Radiasurf 7403 is often used in skincare products, such as lotions, creams, and cleansers, to create a smooth and stable texture.
Additionally, Radiasurf 7403 can act as a mild cleansing agent and can help improve the spreadability of products on the skin.
It's worth noting that Radiasurf 7403 compounds, have been subject to some controversy due to their potential to be contaminated with impurities called 1,4-dioxane, which is considered a possible human carcinogen.

Radiasurf 7403 is the polyethylene glycol ester of oleic acid.
Radiasurf 7403 is used as an emulsifier for personal care and water treatment and as a processing aid in textile industry.
Radiasurf 7403 is a mid-range HLB, surface active agent suggested for use in animal feed, cosmetics, textile chemicals, lubricant, softener, scouring agent), coatings and industrial degreasers.



USAGE AREAS:

Radiasurf 7403 is used in a variety of cosmetic and personal care products due to its emulsifying, cleansing, and texture-enhancing properties.


-Skincare Products:

Radiasurf 7403 is frequently found in lotions, creams, moisturizers, and serums, where it helps to create smooth and stable formulations.
Radiasurf 7403 contributes to the texture, spreadability, and absorption of these products.


-Cleansing Products:

Radiasurf 7403 can be used in facial cleansers, body washes, and soaps.
Radiasurf 7403 aids in the removal of dirt, oils, and impurities from the skin while providing a mild cleansing action.


-Hair Care Products:

Radiasurf 7403 is sometimes included in hair care formulations such as shampoos, conditioners, and styling products.
Radiasurf 7403 can assist in improving the texture and manageability of the hair.


-Makeup Products:

Radiasurf 7403 can be found in various cosmetic formulations, including foundations, primers, and creams.
Radiasurf 7403 helps to create a smooth and blendable texture and can enhance the spreadability and application of these products.


-Sunscreen and Sun Care Products:

Radiasurf 7403 can be used in sunscreens and sun care products to aid in the dispersion and even distribution of UV filters.
Radiasurf 7403 can contribute to the overall stability and performance of these products.




PHYSICAL AND CHEMICAL PROPERTIES:

-Cloud Point: ≤ 6 °C
-Lovibond 1", Yellow: ≤ 10
-Lovibond 1", Red: ≤ 2.5
-Kinematic viscosity at 100°C: ca. 9.5 mm²/s
-Kinematic viscosity at 40°C: ca. 49 mm²/s
-Flash Point: ca. 260 °C
-Pour point: ca. -3 °C



BENEFITS:


-Emulsifying Agent:

Radiasurf 7403 acts as an emulsifier, helping to blend oil and water-based ingredients together.
This property allows for the creation of stable formulations, ensuring that the product remains well-mixed and consistent.


-Improved Texture:

Radiasurf 7403 helps to enhance the texture and spreadability of skincare products.
Radiasurf 7403 can provide a smooth and silky feel when applied to the skin, contributing to a pleasant sensory experience.


-Mild Cleansing:

Radiasurf 7403 can also function as a mild cleansing agent.
Radiasurf 7403 helps to remove dirt, oils, and impurities from the skin's surface without excessive drying or stripping of natural oils.


-Enhanced Skin Penetration:

Due to its emulsifying properties, Radiasurf 7403 can improve the delivery and penetration of active ingredients into the skin.
This can potentially enhance the effectiveness of other beneficial ingredients in a formulation.


-Compatibility with Various Formulations:

Radiasurf 7403 is compatible with a wide range of cosmetic ingredients, making it suitable for use in various formulations such as lotions, creams, serums, and cleansers.




PHYSICAL AND CHEMICAL PROPERTIES:

-Boiling point: >260 °C(lit.)
-density: 1.034 g/mL at 25 °C
-refractive index: n20/D 1.468
-Fp: 113 °C
-storage temp.: Amber Vial, Refrigerator
-solubility: toluene, ethanol and acetone: soluble (dispersible in water)
-form: Oil
-color: Colourless to Light Beige
-Hydrophilic-Lipophilic Balance (HLB): 15.1
-Stability: Light Sensitive
-LogP: 7.185 (est)




STORAGE:

Radiasurf 7403 should be stored at room temperature, typically between 20°C and 25°C (68°F and 77°F).



SYNONYM:

Polyethylene Glycol 8 Oleate
PEG-8 Esters of Oleic Acid
Polyethylene Glycol 8 Monooleate
Macrogol 8 Oleate
Polyoxyethylene (8) Oleate
crodet
hydroxyethyl (Z)-octadec-9-enoate (peg-8)
pegosperse 400 MO
poly(oxy-1,2-ethanediyl), .alpha.-(1-oxo-9-octadecenyl)-.omega.-hydroxy-, (Z)- (8 mol EO average molar ratio)
polyethylene glycol (8) monooleate
polyethylene glycol (8) oleate
polyoxyethylene (8) monooleate
polyoxyethylene (8) oleate
nonisol200
nopalcol1-0
Poly(oxy-1,2-ethanediyl), .alpha.-[(9Z)-1-oxo-9-octadecen-1-yl]-. omega.-hydroxy-
PEG-8 OLEATE
PEG-9 OLEATE
PEG-10 OLEATE
PEG-11 OLEATE
PEG-12 OLEATE