Detergents, Cosmetics, Disinfectants, Pharma Chemicals

METHOXY POLYETHYLENE GLYCOL 3000
Methoxy polyethylene glycol 3000 is a chemical based on methoxy PEG-65.

Methoxy polyethylene glycol 3000 provides lubricity and moisturizing properties to the final product in the formulations of Personal Care and Cosmetic products (For example, shaving foams and shaving gels)

Methoxy polyethylene glycol 3000 is used in pressure-sensitive and thermoplastic adhesives to increase adhesion strength - while the adhesive is still wet.

Methoxy polyethylene glycol 3000 maintains wet adhesion strength in isocyanate and polyester adhesives.

Methoxy polyethylene glycol 3000 is also an intermediate raw material for producing new-generation superplasticizers (Polycarboxylate ones).


Methoxypolyethylene glycol 3000
Methoxy polyethylene glycol 3000

Polyethylene glycol monomethyl ether (MPEG) 3000

What is Methoxy polyethylene glycol 3000?

CARBOWAX MPEG 3000
METHOXY PEG-65
METHOXY PEG-65 [INCI]
MPEG-65
PEG-65 METHYL ETHER
PEG-65 METHYL ETHER [INCI]
POLYETHYLENE GLYCOL 3000 MONOMETHYL ETHER
POLYETHYLENE GLYCOL MONOMETHYL ETHER (MW 1800)
POLYOXYETHYLENE (65) MONOMETHYL ETHER

MPEG 3000 Methoxy polyethylene Glycol by Ataman Chemicals is a methoxy PEG-65-based plasticizer.
Methoxy polyethylene glycol 3000 is used in pressure-sensitive and thermoplastic adhesives.
Methoxy polyethylene Glycol MPEG 3000 possesses lubricity and humectant properties.
Methoxy polyethylene glycol 3000 maintains wet-tack strength.

Methoxy polyethylene glycol 3000 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether (M-PEG) entirely water-soluble.

Methoxy polyethylene glycol 3000 is esterified with methacrylic acid to yield the corresponding polyglycol mono methacrylates used to polymerize polycarboxylate superplasticizers.


Methoxy polyethylene glycol 3000 is a type of Methoxy polyethylene glycol with a Molecular Weight of 3000 that provides enhanced solvency, lubricity, hygroscopicity, and slightly more hydrophobic solvent properties.

Methoxy polyethylene glycol 3000 is an essential raw material in adhesives, chemical intermediates, inks and dye carriers, lubricants, soaps, and detergents​​.

Poly(ethylene glycol) methyl ether 3000 MW:
Methoxy polyethylene glycol 3000 is a chain transfer agent to synthesize amphiphilic block copolymers by metal-free ring-opening oligomerization.
Methoxy polyethylene glycol 3000 is a precursor to prepare retinoic acid-polyethylene glycol nanoassembly as an efficient drug delivery system.
Methoxy polyethylene glycol 3000 is used to prepare diblock copolymer with polylactic acid, which can be applied in tissue engineering and drug delivery.

INCI Name: Methoxy PEG-65

Methoxy poly(ethylene glycol)
Polyethylene glycol monomethyl ether
mPEG
MPEG 3000
Polyglykol M 3000
Methyl polyglycol
Monomethoxy polyethylene glycol 3000
Methoxy Polyethylene Glycol 3000
CARBOWAX Methoxypolyethylene Glycol (MPEG)
Carbowax MPEG 3000
mpeg 3000
Methoxypolyethylene glycols
METHOXY POLYETHYLENE GLYCOL 3000
Poly(ethylene glycol methyl ether)
Poly(ethylene glycol) methyl ether
ETHYLENE GLYCOL 3000 MONOMETHYL ETHER POLYMER

Synonyms: MPEG 3000, mPEG 3000, Polyglykol M 3000, Monomethoxy polyethylene glycol 3000, Methoxy PEG-65, Methoxy Polyethylene Glycol 3000, Methyl polyglycol 3000, POLYETHYLENE GLYCOL MONOMETHYL ETHER, Polyethylenglykolmonomethylether 3000, CARBOWAX Methoxy polyethylene Glycol (MPEG) 3000, Methoxypolyethylene Glycol 3000

Uses of Methoxy polyethylene glycol 3000:
Adhesives
Chemical intermediates
Inks and dye carrier
Lubricants
Soaps and detergents


Composition
Monomethoxy polyethylene glycol 3000

Molecular Structure: CH3(OCH2CH2)nOH

EC / List no.: 618-394-3

CAS no.: 9004-74-4

INCI-designation: Methoxy PEG-65


PRODUCT FUNCTION: Intermediate & process aid

CHEMICAL TYPE: Methoxy Polyethylene glycol

Product data*)
Consistency at 20°C: wax-like
Water content (DIN 51777) % w/w: max. 0.1
Color index Hazen color (10% w/w in water) (EN 1557): max. 30
pH (5 %i w/w in water) (DIN 19268): 5,0 – 7,0
Hydroxyl number (DIN 53240) mg KOH/g: 17.8 - 19.7
Molecular weight g/mol: 2850 - 3150
Pour point (ISO 3016) °C: about 52
Diol content (HPLC) area-%: max. 1,5


APPLICATIONS of Methoxy polyethylene glycol 3000
Chemical synthesis
Concrete Admixture
Construction
Dry mix mortars
General industrial applications
Grinding Aids
Industrial Lubrication
Lubes and Greases
Paint additive manufacturing
Paint additive manufacturing
Plaster Boards
Plastic & elastomer synthesis
Resin synthesis
Superplasticizer



Applications of Methoxy polyethylene glycol 3000:
Methoxy polyethylene glycol 3000 is a raw material for 3rd generation concrete superplasticizers.

Methoxy polyethylene glycol 3000 is an effective component of PCE superplasticizer admixtures.

Methoxy polyethylene glycol 3000 is an intermediate in synthesizing superplasticizers (concrete admixtures) and pigment dispersants.

Methoxy polyethylene glycol 3000 is used as a raw material in producing polycarboxylate ether superplasticizers.

The polycarboxylic acid superplasticizer is prepared with acrylic acid, Methoxy polyethylene glycol 3000, and sodium vinyl sulfonate through the esterification of acrylic acid and Methoxy polyethylene glycol 3000 in the water.


Methoxy polyethylene glycol ether with a molecular weight of 3000 g/mole is commonly used as a chemical intermediate in producing alkyd emulsions and HEUR thickeners.

Methoxy polyethylene glycol 3000 is used for a wide variety of chemical reactions.

Methoxy polyethylene glycol 3000 acts as end-capping and hydrophilic components with isocyanates and polyester

When Methoxy polyethylene glycol 3000 is reacted with unsaturated monomers like acrylic or methacrylic acid, esters are formed, which can be copolymerized to increase hydrophilicity and improve the dispersing properties of polymers in water.

Methoxy polyethylene Glycol (MPEG) 3000 is used in pressure-sensitive and thermoplastic adhesives.
MPEG 3000 possesses lubricity & humectant properties and maintains wet-tack strength

Due to the low concentration of diols in poly-glycol M-types, almost no di-esters form during the reaction with acrylic or methacrylic acid.
In the USA, some M-type polyglycols are used for pharmaceutical applications.



Product properties*)
MPEG 3000 is a waxy white to slightly yellowish solid at room temperature.

MPEG 3000 is available as flakes.

MPEG 3000 is soluble in water and solvents like acetate and methanol.

MPEG 3000 can be considered a high molecular alcohol and, therefore, displays typical chemical reactions of alcohols.


MPEG 3000 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether (M-PEG) entirely water-soluble.


MPEG 3000 PRODUCT FUNCTION: Intermediate





Storage
When stored in a cold, dry place in a closed container, MPEG 3000 can be kept for at least two years.


Regulatory process names
Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy-


IUPAC names
2-methoxyethanol

Dodecaethylene glycol monomethyl ether

METHOXY POLYETHYLENE GLYCOL 3000

Methoxy Polyethylene Glycol 3000

Polietilenglicolmonometileter

Poly(oxy-1,2-ethanediyl), .alpha.-methyl-.omega.-hydroxy-

Poly(oxy-1,2-ethanediyl), a-methyl-w-hydroxy-

POLY(OXY-1,2-ETHANEDIYL), α-METHYL-ω-HYDROXY-

Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy-

POLYETHYLENE GLYCOL MONOMETHYL ETHER

polyethylene glycol monomethyl ether

Polyethylene glycol monomethyl ether; Carbowax Sentry Methoxypolyethylene glycol

Polyethylenglykolmonomethylether



Trade names
Dodecaethylene glycol monomethyl ether

Other names
Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy

polyethylene(4-6)glycolmonomethylether


OTHER PRODUCTS OF ATAMAN CHEMICALS THAT MIGHT BE OF INTEREST

MPEG 200
MPEG 300
MPEG 400
MPEG 600
MPEG 1000
MPEG 1500
MPEG 2000
MPEG 3000
MPEG 4000
MPEG 5000
MPEG 6000

This information is based on Ataman's present knowledge and is intended to provide general notes on our products and their uses.
It should not, therefore, be construed as guaranteeing specific properties of the products described or their suitability for a particular application.
Any existing industrial property rights must be observed.
The quality of our products is guaranteed under our General Conditions of Sale.
Please check our website: www.atamankimya.com











METHOXY POLYETHYLENE GLYCOL 500
METHOXY POLYETHYLENE GLYCOL 500

Methoxy Polyethylene glycol 500

Methoxypolyethylene glycol 500

mPEG 500

MPEG 500



What is Methoxy Polyethylene glycol 500?

Methoxy Polyethylene glycol 500 by Ataman Chemicals is a methoxy PEG-10-based plasticizer.
Methoxy Polyethylene glycol 500 is used in pressure-sensitive and thermoplastic adhesives.
Methoxy Polyethylene Glycol MPEG 500 possesses lubricity and humectant properties.
Methoxy Polyethylene glycol 500 maintains wet-tack strength.

Methoxy Polyethylene glycol 500 is a linear, mono hydroxy-functional Polyethylene glycol monomethyl ether (M-PEG) entirely water-soluble.

Methoxy Polyethylene glycol 500 is esterified with methacrylic acid to yield the corresponding polyglycol mono methacrylates used to polymerize polycarboxylate superplasticizers.


Methoxy Polyethylene glycol 500 is a type of Methoxy Polyethylene glycol with a Molecular Weight of 500 that provides enhanced solvency, lubricity, hygroscopicity, and slightly more hydrophobic solvent properties.

Methoxy Polyethylene glycol 500 is an essential raw material in adhesives, chemical intermediates, inks and dye carriers, lubricants, soaps, and detergents​​.

Poly(ethylene glycol) methyl ether 500 MW:
MPEG 500 is a chain transfer agent to synthesize amphiphilic block copolymers by metal-free ring-opening oligomerization.
MPEG 500 is a precursor to prepare retinoic acid-Polyethylene glycol nanoassembly as an efficient drug delivery system.
MPEG 500 is used to prepare diblock copolymer with polylactic acid, which can be applied in tissue engineering and drug delivery.

INCI Name: Methoxy PEG-10

Methoxy poly(ethylene glycol)
Polyethylene glycol monomethyl ether
mPEG
MPEG 500
Polyglykol M 500
Methyl polyglycol
Monomethoxy Polyethylene glycol 500
Methoxy Polyethylene Glycol 500
CARBOWAX Methoxy Polyethylene Glycol (MPEG)
Carbowax MPEG 500
mpeg 500
Methoxy Polyethylene glycols
METHOXY Polyethylene GLYCOL 500
Poly(ethylene glycol methyl ether)
Poly(ethylene glycol) methyl ether
ETHYLENE GLYCOL 500 MONOMETHYL ETHER POLYMER

Synonyms: MPEG 500, mPEG 500, Polyglykol M 500, Monomethoxy Polyethylene glycol 500, Methoxy PEG-10, Methoxy Polyethylene Glycol 500, Methyl polyglycol 500, Polyethylene GLYCOL MONOMETHYL ETHER, Polyethylenglykolmonomethylether 500, CARBOWAX Methoxy Polyethylene Glycol (MPEG) 500, Methoxy Polyethylene Glycol 500

Uses of Methoxy Polyethylene glycol 500:
Adhesives
Chemical intermediates
Inks and dye carrier
Lubricants
Soaps and detergents


Composition
Monomethoxy Polyethylene glycol 500

Molecular Structure: CH3(OCH2CH2)nOH

EC / List no.: 618-394-3

CAS no.: 9004-74-4

INCI-designation: Methoxy PEG-10


PRODUCT FUNCTION: Intermediate & process aid

CHEMICAL TYPE: Methoxy Polyethylene glycol


Product data*)
Water content (DIN 51777) % m/m: max. 0.5
Color index [APHA] 10 % in water (EN 1557): max. 30
pH (5 % w/w in water) (DIN 19268): 5 – 7
Hydroxyl number (DIN 53240) mg KOH/g: 106 – 119
Molecular weight g/mol: 470 – 530
Pour point (ISO 3016) °C: about 12
Density at 50°C (DIN 51757) g/cm³: 1,072 – 1,076
Refractive index at 20°C (DIN 51423, Part 2): 1,460 – 1,462
Viscosity at 50°C (DIN 51562) mm²/s: 16 – 20


APPLICATIONS of Methoxy Polyethylene glycol 500
Chemical synthesis
Concrete Admixture
Construction
Dry mix mortars
General industrial applications
Grinding Aids
Industrial Lubrication
Lubes and Greases
Paint additive manufacturing
Paint additive manufacturing
Plaster Boards
Plastic & elastomer synthesis
Resin synthesis
Superplasticizer



Applications of Methoxy Polyethylene glycol 500:
Methoxy Polyethylene glycol 500 is a raw material for 3rd generation concrete superplasticizers.

Methoxy Polyethylene glycol 500 is an effective component of PCE superplasticizer admixtures.

Methoxy Polyethylene glycol 500 is an intermediate in synthesizing superplasticizers (concrete admixtures) and pigment dispersants.

Methoxy Polyethylene glycol 500 is used as a raw material in producing polycarboxylate ether superplasticizers.

The polycarboxylic acid superplasticizer is prepared with acrylic acid, MPEG 500, and sodium vinyl sulfonate through the esterification of acrylic acid and MPEG 500 in the water.


Methoxy Polyethylene glycol ether with a molecular weight of 500 g/mole is commonly used as a chemical intermediate in producing alkyd emulsions and HEUR thickeners.

MPEG 500 is used for a wide variety of chemical reactions.

MPEG 500 acts as end-capping and hydrophilic components with isocyanates and polyester

When Methoxy Polyethylene glycol 500 is reacted with unsaturated monomers like acrylic or methacrylic acid, esters are formed, which can be copolymerized to increase hydrophilicity and improve the dispersing properties of polymers in water.

Methoxy Polyethylene Glycol (MPEG) 500 is used in pressure-sensitive and thermoplastic adhesives.
MPEG 500 possesses lubricity & humectant properties and maintains wet-tack strength

Due to the low concentration of diols in poly-glycol M-types, almost no di-esters form during the reaction with acrylic or methacrylic acid.
In the USA, some M-type polyglycols are used for pharmaceutical applications.



Product properties*)
Methoxy Polyethylene glycol 500 is a waxy white to slightly yellowish solid at room temperature.

Methoxy Polyethylene glycol 500 can be supplied as melt in heated tank trucks or solid in steel drums.

Methoxy Polyethylene glycol 500 is soluble in water and solvents like acetate and methanol.

Methoxy Polyethylene glycol 500 can be considered a high molecular alcohol and, therefore, displays typical chemical reactions of alcohols.


Methoxy Polyethylene glycol 500 is a linear, mono hydroxy-functional Polyethylene glycol monomethyl ether (M-PEG) entirely water-soluble.


MPEG 500 PRODUCT FUNCTION: Intermediate





Storage
When stored in a cold, dry place in a closed container, MPEG 500 can be kept for at least two years.


Regulatory process names
Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy-


IUPAC names
2-methoxyethanol

Dodecaethylene glycol monomethyl ether

METHOXY Polyethylene GLYCOL 500

Methoxy Polyethylene Glycol 500

Polietilenglicolmonometileter

Poly(oxy-1,2-ethanediyl), .alpha.-methyl-.omega.-hydroxy-

Poly(oxy-1,2-ethanediyl), a-methyl-w-hydroxy-

POLY(OXY-1,2-ETHANEDIYL), α-METHYL-ω-HYDROXY-

Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy-

Polyethylene GLYCOL MONOMETHYL ETHER

Polyethylene glycol monomethyl ether

Polyethylene glycol monomethyl ether; Carbowax Sentry Methoxy Polyethylene glycol

Polyethylenglykolmonomethylether



Trade names
Dodecaethylene glycol monomethyl ether

Other names
Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy

Polyethylene(4-6)glycolmonomethylether


This information is based on Ataman's present knowledge and is intended to provide general notes on our products and their uses.
It should not, therefore, be construed as guaranteeing specific properties of the products described or their suitability for a particular application.
Any existing industrial property rights must be observed.
The quality of our products is guaranteed under our General Conditions of Sale.
Please check our website: www.atamankimya.com
 
METHOXY POLYETHYLENE GLYCOL 750
What is MPEG 750?

MPEG 750 Methoxy polyethylene Glycol by Ataman Chemicals is a methoxy PEG-16-based plasticizer.
Methoxy Polyethylene Glycol 750 is used in pressure-sensitive and thermoplastic adhesives.
Methoxy Polyethylene Glycol 750 possesses lubricity and humectant properties.
Methoxy Polyethylene Glycol 750 maintains wet-tack strength.

Methoxy Polyethylene Glycol 750 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether (M-PEG) entirely water-soluble.

Methoxy Polyethylene Glycol 750 is esterified with methacrylic acid to yield the corresponding polyglycol mono methacrylates used to polymerize polycarboxylate superplasticizers.


Methoxy Polyethylene Glycol 750 is a type of Methoxy polyethylene glycol with a Molecular Weight of 750 that provides enhanced solvency, lubricity, hygroscopicity, and slightly more hydrophobic solvent properties.

Methoxy Polyethylene Glycol 750 is an essential raw material in adhesives, chemical intermediates, inks and dye carriers, lubricants, soaps, and detergents​​.

Poly(ethylene glycol) methyl ether 750 MW:
Methoxy Polyethylene Glycol 750 is a chain transfer agent to synthesize amphiphilic block copolymers by metal-free ring-opening oligomerization.
Methoxy Polyethylene Glycol 750 is a precursor to prepare retinoic acid-polyethylene glycol nanoassembly as an efficient drug delivery system.
Methoxy Polyethylene Glycol 750 is used to prepare diblock copolymer with polylactic acid, which can be applied in tissue engineering and drug delivery.

INCI Name: Methoxy PEG-16

Methoxy poly(ethylene glycol)
Polyethylene glycol monomethyl ether
mPEG
MPEG 750
Polyglykol M 750
Methyl polyglycol
Monomethoxy polyethylene glycol 750
Methoxy Polyethylene Glycol 750
CARBOWAX Methoxypolyethylene Glycol (MPEG)
Carbowax MPEG 750
mpeg 750
Methoxypolyethylene glycols
METHOXY POLYETHYLENE GLYCOL 750
Poly(ethylene glycol methyl ether)
Poly(ethylene glycol) methyl ether
ETHYLENE GLYCOL 750 MONOMETHYL ETHER POLYMER

Synonyms: MPEG 750, mPEG 750, Polyglykol M 750, Monomethoxy polyethylene glycol 750, Methoxy PEG-16, Methoxy Polyethylene Glycol 750, Methyl polyglycol 750, POLYETHYLENE GLYCOL MONOMETHYL ETHER, Polyethylenglykolmonomethylether 750, CARBOWAX Methoxy polyethylene Glycol (MPEG) 750, Methoxypolyethylene Glycol 750

Uses of MPEG 750:
Adhesives
Chemical intermediates
Inks and dye carrier
Lubricants
Soaps and detergents


Composition
Monomethoxy polyethylene glycol 750

Molecular Structure: CH3(OCH2CH2)nOH

EC / List no.: 618-394-3

CAS no.: 9004-74-4

INCI-designation: Methoxy PEG-16


PRODUCT FUNCTION: Intermediate & process aid

CHEMICAL TYPE: Methoxy Polyethylene glycol


APPLICATIONS of Methoxy Polyethylene Glycol 750
Chemical synthesis
Concrete Admixture
Construction
Dry mix mortars
General industrial applications
Grinding Aids
Industrial Lubrication
Lubes and Greases
Paint additive manufacturing
Paint additive manufacturing
Plaster Boards
Plastic & elastomer synthesis
Resin synthesis
Superplasticizer



Applications of Methoxy Polyethylene Glycol 750:
Methoxy Polyethylene Glycol 750 is a raw material for 3rd generation concrete superplasticizers.

Methoxy Polyethylene Glycol 750 is an effective component of PCE superplasticizer admixtures.

Methoxy Polyethylene Glycol 750 is an intermediate in synthesizing superplasticizers (concrete admixtures) and pigment dispersants.

Methoxy Polyethylene Glycol 750 is used as a raw material in producing polycarboxylate ether superplasticizers.

The polycarboxylic acid superplasticizer is prepared with acrylic acid, Methoxy Polyethylene Glycol 750, and sodium vinyl sulfonate through the esterification of acrylic acid and Methoxy Polyethylene Glycol 750 in the water.


Methoxy polyethylene glycol ether with a molecular weight of 750 g/mole is commonly used as a chemical intermediate in producing alkyd emulsions and HEUR thickeners.

Methoxy Polyethylene Glycol 750 is used for a wide variety of chemical reactions.

Methoxy Polyethylene Glycol 750 acts as end-capping and hydrophilic components with isocyanates and polyester

When Methoxy Polyethylene Glycol 750 is reacted with unsaturated monomers like acrylic or methacrylic acid, esters are formed, which can be copolymerized to increase hydrophilicity and improve the dispersing properties of polymers in water.

Methoxy polyethylene Glycol (MPEG) 750 is used in pressure-sensitive and thermoplastic adhesives.
Methoxy Polyethylene Glycol 750 possesses lubricity & humectant properties and maintains wet-tack strength

Due to the low concentration of diols in poly-glycol M-types, almost no di-esters form during the reaction with acrylic or methacrylic acid.
In the USA, some M-type polyglycols are used for pharmaceutical applications.



Product properties*)
Methoxy Polyethylene Glycol 750 is a waxy white to slightly yellowish solid at room temperature.

Methoxy Polyethylene Glycol 750 can be supplied as melt in heated tank trucks or solid in steel drums.

Methoxy Polyethylene Glycol 750 is soluble in water and solvents like acetate and methanol.

Methoxy Polyethylene Glycol 750 can be considered a high molecular alcohol and, therefore, displays typical chemical reactions of alcohols.


Methoxy Polyethylene Glycol 750 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether (M-PEG) entirely water-soluble.


Methoxy Polyethylene Glycol 750 PRODUCT FUNCTION: Intermediate


Product data*)
Water content (DIN 51777) % m/m: max. 0.5
Color index [APHA] 10 % w/w in water (ISO 6271): max. 30
pH (5 % w/w in water) (DIN 19268): 5 – 7
Hydroxyl number (DIN 53240) mg KOH/g: 72 – 78
Molecular weight g/mol: 720 – 780
Pour point (ISO 3016) °C: about 27
Density at 50°C (DIN 51757) g/cm³: 1.081 – 1.085
Viscosity at 50°C (DIN 51562) mm²/s: 29 – 35
Diol content (HPLC) area-% typical: 0.5- 1.0


Storage
When stored in a cold, dry place in a closed container, Methoxy Polyethylene Glycol 750 can be kept for at least two years.


Regulatory process names
Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy-


IUPAC names
2-methoxyethanol

Agent I3C8

Dodecaethylene glycol monomethyl ether

METHOXY POLYETHYLENE GLYCOL 750

Methoxy Polyethylene Glycol 750

Polietilenglicolmonometileter

Poly(oxy-1,2-ethanediyl), .alpha.-methyl-.omega.-hydroxy-

Poly(oxy-1,2-ethanediyl), a-methyl-w-hydroxy-

POLY(OXY-1,2-ETHANEDIYL), α-METHYL-ω-HYDROXY-

Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy-

POLYETHYLENE GLYCOL MONOMETHYL ETHER

polyethylene glycol monomethyl ether

Polyethylene glycol monomethyl ether; Carbowax Sentry Methoxypolyethylene glycol

Polyethylenglykolmonomethylether



Trade names
Dodecaethylene glycol monomethyl ether

Other names
Poly(oxy-1,2-ethanediyl), α-methyl-ω-hydroxy

polyethylene(4-6)glycolmonomethylether


This information is based on Ataman's present knowledge and is intended to provide general notes on our products and their uses.
It should not, therefore, be construed as guaranteeing specific properties of the products described or their suitability for a particular application.
Any existing industrial property rights must be observed.
The quality of our products is guaranteed under our General Conditions of Sale.
Please check our website: www.atamankimya.com











METHOXY PROPANOL
Methoxy propanol has 100% water solubility and is ideally suited as a coupling agent in a wide range of solvent systems.
Methoxy propanol has a high water solubility, excellent solvent with good coupling properties making Methoxy propanol suitable for cleaning solutions and coating applications.
Methoxy propanol is glycol ethers based on propylene oxide and methanol.

CAS Number: 107-98-2
EC Number: 203-539-1
Chemical Formula: CH3OCH2CH(OH)CH3
Molar Mass: 90.12 g/mol

Methoxy propanol is a colorless liquid with a slight ethereal odor that is used as an excellent industrial solvent with low toxicity and has strong solubility for polar and unpolar materials, which can be used for advanced paints, printing inks as well as some other polymers including glycol acid resin, acrylic acid resin, epoxy resin and nitrocellulose.

Methoxy propanol is an organic solvent with a wide variety of industrial and commercial uses.
Similar to other glycol ethers, Methoxy propanol is used as a carrier/solvent in printing/writing inks and paints/coatings.

Methoxy propanol also finds use as an industrial and commercial paint stripper.
Methoxy propanol is used as an antifreeze in diesel engines.

Methoxy propanol is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 to < 1 000 000 tonnes per annum.
Methoxy propanol is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Methoxy propanol , a medium-boiling glycol ether, is an active solvent for cellulose acetate butyrate, nitrocellulose, epoxy, phenolic, acrylic, and alkyd resins.
Methoxy propanol is used in a variety of coating, printing ink, and cleaning applications.

Methoxy propanol, a glycol ether, can be synthesized by reacting propylene oxide with methanol in the presence of ZnMgAl (zinc-magnesium-aluminium) catalysts.
Methoxy propanol degradation by microorganisms in different soil types has been investigated.
An oral reference dose (RfD) and an inhalation reference concentration (RfC) values of Methoxy propanol have been obtained from inhalation studies in F344 rats and B6C3F1 mice.

Methoxy propanol is glycol ethers based on propylene oxide and methanol.
Methoxy propanol is solvent having a bi-functional nature (ether-alcohol and the respective acetate).
Methoxy propanol is clear liquid, with PGMEA having a pleasant, fruity odour.

Methoxy propanol, also known as Propylene glycol methyl ether, is a clear, colourless liquid with a faint ether-like odour.
Methoxy propanol is soluble in water and has moderate volatility.

Methoxy propanol is a propylene oxide-based glycol ether which is fast evaporating and hydrophilic.
Methoxy propanol has low surface tension as well as excellent solvency and coupling abilities.

Methoxy propanol is produced by reacting propylene oxide with methanol using a catalyst.

Methoxy propanol appears as a colorless liquid.
Methoxy propanol is flash point near 89 °F.
Methoxy propanol is used as a solvent and as an antifreeze agent.

Methoxy propanol is the fastest evaporating solvent of the glycol ether family.
Methoxy propanol has a high water solubility, excellent solvent with good coupling properties making Methoxy propanol suitable for cleaning solutions and coating applications.
Methoxy propanol has 100% water solubility and is ideally suited as a coupling agent in a wide range of solvent systems.

Methoxy propanol is a clear, colorless liquid with an ether-like odor.
Methoxy propanol is completely soluble in water, with moderate volatility and is used as a solvent.

Methoxy propanol is a widely used organic solvent in industrial and commercial applications.
Like other glycol ethers, Methoxy propanol is used as a carrier/solvent in printing/writing inks and paints/coatings.

Methoxy propanol is also used as an industrial and commercial paint stripper.
Methoxy propanol is used as an antifreeze in diesel engines.

Methoxy propanol is the fastest evaporating solvent in the glycol ether family.
Methoxy propanol offers very high water solubility and active solvency, and is widely used in coating and cleaning applications.
Methoxy propanol offers better viscosity reduction than heavier molecular weight glycol ethers and is particularly effective in epoxy and high solids acrylic systems.

Methoxy propanol is a colourless highly flammable liquid that is soluble in water.
Methoxy propanol is a methoxy alcohol derivative with the formula of C4H10O2.

Methoxy propanol is an organic solvent with a variety of industrial and commercial uses.

Similar to other glycol ethers, Methoxy propanol is used as a carrier solvent in printing inks.
Furthermore is Methoxy propanol used as industrial and commercial paint stripper, paints, varnishes and inks.

Propylene glycol monomethyl ether and ethylene glycol ether are both glycol ether solvent.
From human toxicity’s perspective, toxicity of propylene glycol ether is lower than that of ethylene glycol ether, thereby making Methoxy propanol as low toxicity ether.

Methoxy propanol has a slight glycol odor but is not strongly irritating, making Methoxy propanol usage wider and safer.
As there are both ether and hydroxyl groups in Methoxy propanol molecular structure, Methoxy propanol has excellent solubility and possesses ideal rate of evaporation and reactivity, leading to a wide range of applications.

Methoxy propanol is a water-soluble solvent with unique properties making Methoxy propanol ideal for use in a wide range of applications, including those that require a high degree of solvency, quick evaporation, and good surface tension reduction.

Methoxy propanol is an effective product for use in the paints and coatings industry, as well as being a good solvent, Methoxy propanol can promote good film surfaces by maintaining dissolved resins during the evaporation process.
Methoxy propanol provides good solvency for a wide variety of resins including acrylic, epoxies, polyesters, nitrocellulose and polyurethanes.
For cleaners they offer low toxicity, good coupling, wetting and penetration, and high solvency for polar and nonpolar materials.

Methoxy propanol, also known as 1-methoxy-2-propanol, is a colorless organic chemical compound.
Generally, Methoxy propanol is medium boiling glycol ether that is categorized under P-series glycol ether group.

Methoxy propanol is produced by the reaction between propylene oxide and methanol which is carried out in presence catalyst.
Methoxy propanol are used prevalently as an organic solvent in commercial as well as industrial applications such as printing ink, chemical, agricultural, and automotive, among others.

The physico-chemical properties of Methoxy propanol such as excellent solvent activity, high dilution ratio, medium evaporation rate, and readily biodegradable nature, among other owing to which Methoxy propanol appears as suitable alternative for petroleum based solvents.
Thereby, Methoxy propanol leads to increase in demand for Methoxy propanol in several industries such as chemical, automotive and paint & coating is increased in order to support sustainability development

Methoxy propanol Market Segmentation:

Based on product type, global Methoxy propanol market is segmented into;
PM (Propylene Glycol Mono Methyl Ether)
DPM (Dipropylene Glycol Mono Methyl Ether)
TPM (Tripropylene Glycol Mono Methyl Ether)

Based on application, global Methoxy propanol market is segmented into;
Chemical intermediate
Solvent
Coalescing agent
Coatings
Electronics
TFT-LCD Manufacturing
Semiconductor
Others

Uses of Methoxy propanol:
Methoxy propanol is an organic solvent with a wide variety of industrial and commercial uses.
Similar to other glycol ethers, Methoxy propanol is used as a carrier/solvent in printing/writing inks and paints/coatings.
Methoxy propanol also finds use as an industrial and commercial paint stripper.

Methoxy propanol is used as intermediates and in formulations in industrial, professional or consumer applications, mainly in surface coatings, printing inks, cleaners, agrochemical or de-icing/anti-icing formulations.
Methoxy propanol is also used as extractants, as coalescing agents and as flow improvers in waterbased paints.

Methoxy propanol is active solvent for solvent-based coatings.
Methoxy propanol is active and tail solvent for solvent based gravure and flexographic printing inks.

Methoxy propanol is coupling agent in solvent blends for water-based gravure, flexographic, and silk screen printing inks.
Methoxy propanol is carrier solvent for ball point and felt tip writing pen inks.

Methoxy propanol is coupling agent and solvent for household and industrial cleaners, rust removers, and hard surface cleaners.
Methoxy propanol is solvent for agricultural pesticides, deactivator and emollient for livestock pesticides

Methoxy propanol is used as a solvent in paints, inks, nail polish removers, and cleaning agents.
Methoxy propanol is also used in finishing leather and in electronics and agriculture.
Methoxy propanol is used to make lacquers and paints, as a solvent for resins, celluloses, acrylics, dyes, and inks (gravure, flexographic and silk screening), as antifreeze, and in household cleaners and spot removers.

Methoxy propanol is chiefly used in manufacture of lacquers and paints.
Methoxy propanol has been used as an antifreeze material, principally in ebullient cooling systems and in some heavy-duty diesel engines.

Methoxy propanol is as a solvent component in paints and printing inks, improves the wetting of some pigments and colorants.
Methoxy propanol has a good solvency for cellulose nitrate, cellulose ethers, chlorinated rubber, poly(vinyl acetate), poly(vinyl butyral), ketone and ketone-formaldehyde resins, shellac, colophony, phenol-, melamine-, and urea-formaldehyde resins, alkyd resins, polyacrylates, polymethacrylates, castor oil, linseed oil, and some vinyl chloride copolymers.

Being a moderately volatile solvent, Methoxy propanol improves paint penetration, flow properties, and the gloss of paint coats.
Methoxy propanol also prevents blushing and formation of fish eyes and blisters.
Addition of Methoxy propanol does not delay the drying of paint systems.

Consumer Uses:
Cleaning agent
Corrosion inhibitor
Diluent
Dispersing agent
Functional fluids (closed systems)
Intermediates
Not Known or Reasonably Ascertainable
Other
Other (specify)
Paint additives and coating additives not described by other categories
Pigment
Pigments
Processing aids, specific to petroleum production
Solvent
UV stabilizer
Viscosity adjustors

Other Consumer Uses:
Methoxy propanol is used in the following products: coating products, washing & cleaning products, anti-freeze products, cosmetics and personal care products, biocides (e.g. disinfectants, pest control products) and inks and toners.
Other release to the environment of Methoxy propanol is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.

Widespread uses by professional workers:
Methoxy propanol is used in the following products: coating products, washing & cleaning products, plant protection products, adhesives and sealants, fillers, putties, plasters, modelling clay and inks and toners.
Methoxy propanol has an industrial use resulting in manufacture of another substance (use of intermediates).

Methoxy propanol is used in the following areas: printing and recorded media reproduction, building & construction work and health services.
Methoxy propanol is used for the manufacture of: machinery and vehicles and rubber products.
Other release to the environment of Methoxy propanol is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Uses at industrial sites:
Methoxy propanol is used in the following products: coating products, semiconductors, fillers, putties, plasters, modelling clay and washing & cleaning products.
Methoxy propanol has an industrial use resulting in manufacture of another substance (use of intermediates).

Methoxy propanol is used in the following areas: building & construction work.
Methoxy propanol is used for the manufacture of: chemicals, machinery and vehicles, electrical, electronic and optical equipment and fabricated metal products.
Release to the environment of Methoxy propanol can occur from industrial use: in processing aids at industrial sites and as an intermediate step in further manufacturing of another substance (use of intermediates).

Industry Uses:
Adhesives and sealant chemicals
Corrosion inhibitor
Diluent
Dispersing agent
Functional fluids (closed systems)
Intermediate
Intermediates
Not Known or Reasonably Ascertainable
Other (specify)
Paint additives and coating additives not described by other categories
Photosensitive agent
Pigment
Pigments
Sealant (barrier)
Solvent
Solvents (for cleaning or degreasing)
Solvents (which become part of product formulation or mixture)
UV stabilizer
Viscosity adjustors

Industrial Processes with risk of exposure:
Painting (Solvents)
Plastic Composites Manufacturing
Leather Tanning and Processing
Textiles (Printing, Dyeing, or Finishing)
Silk-Screen Printing

Applications of Methoxy propanol:
Methoxy propanol isprimarily used as a chemical building block for the production of Methoxy propanol acetate.
Methoxy propanol is also used as a solvent in manufacturing processes for the chemical, automotive and agricultural industries and in paint, lacquer and varnishes.
Methoxy propanol is used as a coalescing agent in water-based paints and inks where Methoxy propanol promotes polymer fusion during the drying process.

Methoxy propanol is formulated into a wide range of cleaners for industrial and commercial use such as those for ovens, glass, hard surfaces, floors, carpets and upholstery, as well as in speciality sanitation products such as swimming pool cleaners.
Methoxy propanol is also present in many everyday products such as polish, laundry aids, caulk, sealants, pesticides, inks for ballpoint and felt-tip pens, synthetic resin and rubber adhesives.

Other Applications:
Architectural coatings
Auto OEM
Auto refinish
Automotive
Building materials
Commerical printing inks
General industrial coatings
Graphic arts
Janitorial & household cleaners
Marine
Paints & coatings
Protective coatings
Wood coatings

Benefits and Applications of Methoxy propanol:

Coatings:
Methoxy propanol provides good solvency for a wide variety of resins including acrylic, epoxies, alkyds, polyesters, nitrocellulose and polyurethanes.
Key properties for coating reformulation also include complete water miscibility and good coupling ability.
Methoxy propanol is a good substitute for E-series solvents; particularly, Ethylene glycol methyl ether and Ethylene glycol ethyl ether.

Cleaners:
Low toxicity, surface tension reduction, and fast evaporation are some of the benefits of using Methoxy propanol in cleaning formulations.
Methoxy propanol also provides good solvency for polar and non polar materials.
Methoxy propanol can also be used in combination with Dowanol PnB / Arcosolv PnB in glass cleaning formulations.

Chemical Intermediate:
Methoxy propanol can be used in combination with other glycol ethers or solvents to custom tailor properties to meet the full requirements of the formulation.
Methoxy propanol has a very low content of primary alcohol, generally below 2%.

The primary alcohol isomer is more reactive than the secondary alcohol isomer.
Low primary alcohol content minimizes side product formation.

Electronics:
Methoxy propanol is used in conjunction with other solvents in the manufacture of laminates which are used to make circuit boards.
Additionally, Methoxy propanol may be used in the cleaning and removal of solder flux and masks.

Other Applications:
The properties listed in the previous section also support the use of Methoxy propanol in agricultural, cosmetic, ink, textile and adhesives products.

Key attributes of Methoxy propanol:
Excellent solvent activity
Good coupling efficiency
High dilution ratio
Inert - Food use with limitations
Inert - Nonfood use
Medium evaporation rate
Miscible with water and most organic liquids
Non-HAP
Non-SARA
Readily biodegradable

Manufacturing Methods of Methoxy propanol:
Ethers are prepared commercially by reacting propylene oxide with alcohol of choice in presence of catalyst.
They also may be prepared by direct alkylation of selected glycol with appropriate alkylating agent such as dialkyl sulfate in presence of alkali.

Methoxy propanol is produced by reacting propylene oxide with methanol.

General Manufacturing Information of Methoxy propanol:

Industry Processing Sectors:
Adhesive Manufacturing
All Other Basic Organic Chemical Manufacturing
Computer and Electronic Product Manufacturing
Construction
Fabricated Metal Product Manufacturing
Furniture and Related Product Manufacturing
Miscellaneous Manufacturing
Not Known or Reasonably Ascertainable
Oil and Gas Drilling, Extraction, and Support activities
Other (requires additional information)
Paint and Coating Manufacturing
Petrochemical Manufacturing
Plastics Material and Resin Manufacturing
Plastics Product Manufacturing
Printing Ink Manufacturing
Synthetic Dye and Pigment Manufacturing
Textiles, apparel, and leather manufacturing
Transportation Equipment Manufacturing
Wholesale and Retail Trade

In order to identify users of Methoxy propanol and potential exposures, a chemical registration database maintained in Switzerland was analysed.
The database contains information on the composition of products (qualitative and quantitative), the field of use, the year of registration and the domain of commercial applications (public or professional).

Identification of potential exposures in Switzerland was carried out.
Out of a total of 150,000 products, 2334 were found to contain Methoxy propanol and most contained between 1% and 10% Methoxy propanol.

There was a great increase in the number of products declared between 1983 and 1991.
The principal fields of use were in inks, varnishes and paints.

Handling and storage of Methoxy propanol:
Methoxy propanol and its vapours are flammable.
Methoxy propanol should be stored in a cool, well-ventilated place away from sources of ignition.
Methoxy propanol must be isolated from incompatible materials such as strong oxidizers, bases and acids.

Methoxy propanol is a mild, but usually temporary, irritant to the eyes.
Repeated or prolonged contact with the skin may cause irritation, and in very large amounts skin absorption may cause drowsiness or dizziness.

High levels of Methoxy propanol vapour may produce eye, nose and throat irritation, and at very high levels may produce anaesthetic or narcotic effects.
Unnecessary exposure should be prevented by appropriate work practices and engineering controls, adequate ventilation and by the use of approved personal protective equipment including gloves, clothing and safety goggles and the use of respirators where appropriate to the task being carried out.

Precautions for safe handling of Methoxy propanol:

Advice on safe handling:
Work under hood. Do not inhale substance/mixture.
Avoid generation of vapours/aerosols.

Advice on protection against fire and explosion:
Keep away from open flames, hot surfaces and sources of ignition.
Take precautionary measures against static discharge.

Hygiene measures:
Change contaminated clothing. Wash hands after working with substance.

Conditions for safe storage, including any incompatibilities:

Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Keep away from heat and sources of ignition.

Air sensitive.
Forms explosive peroxides on prolonged storage May form peroxides on contact with air.

Storage class:
Storage class (TRGS 510): 3: Flammable liquids

Stability and reactivity of Methoxy propanol:

Reactivity:
Can violently decompose at elevated temperatures Stable under recommended storage conditions.
Vapor/air-mixtures are explosive at intense warming.

Chemical stability:
Sensitive to air.
Methoxy propanol is chemically stable under standard ambient conditions (room temperature).

May form peroxides on prolonged storage.
Date container and periodically test for peroxides.

Possibility of hazardous reactions:
No data available

Conditions to avoid:
May form explosive peroxides.

Incompatible materials:
Strong oxidizing agents

First aid measures of Methoxy propanol:

General advice:
Show Methoxy propanol safety data sheet to the doctor in attendance.

If inhaled:
After inhalation:
Fresh air.
Call in physician.

In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.

In case of eye contact:

After eye contact:
Rinse out with plenty of water.
Remove contact lenses.

If swallowed:

After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.

Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling.

Indication of any immediate medical attention and special treatment needed:
No data available

Firefighting measures of Methoxy propanol:

Suitable extinguishing media:
Water Foam Carbon dioxide (CO2) Dry powder

Unsuitable extinguishing media:
For Methoxy propanol no limitations of extinguishing agents are given.

Special hazards arising from Methoxy propanol or mixture:
Carbon oxides

Flash back possible over considerable distance.
Container explosion may occur under fire conditions.

Vapors may form explosive mixture with air.
May form peroxides of unknown stability.

Combustible.
Vapors are heavier than air and may spread along floors.

Forms explosive mixtures with air at elevated temperatures.
Development of hazardous combustion gases or vapours possible in the event of fire.

Advice for firefighters:
In the event of fire, wear self-contained breathing apparatus.

Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.

Accidental release measures of Methoxy propanol:

Personal precautions, protective equipment and emergency procedures:

Advice for non-emergency personnel:
Do not breathe vapors, aerosols.
Avoid substance contact.

Ensure adequate ventilation.
Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental precautions:
Do not let product enter drains.
Risk of explosion.

Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills. Observe possible material restrictions.

Take up with liquid-absorbent material (e.g. Chemizorb).
Dispose of properly.
Clean up affected area.

Identifiers of Methoxy propanol:
CAS Number: 107-98-2
ChemSpider: 7612
ECHA InfoCard: 100.003.218
PubChem CID: 7900
UNII: 74Z7JO8V3U
CompTox Dashboard (EPA): DTXSID8024284
InChI: InChI=1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3
Key: ARXJGSRGQADJSQ-UHFFFAOYSA-N
SMILES: CC(O)COC

Synonym(s): Propylene glycol methyl ether, Propyleneglycol monomethyl ether
Linear Formula: CH3CH(OH)CH2OCH3
CAS Number: 107-98-2
Molecular Weight: 90.12
Beilstein: 1731270
EC Number: 203-539-1
MDL number: MFCD00004537
PubChem Substance ID: 57651153

CAS number: 107-98-2
EC index number: 603-064-00-3
EC number: 203-539-1
Hill Formula: C₄H₁₀O₂
Chemical formula: CH₃OCH₂CH(OH)CH₃
Molar Mass: 90.12 g/mol
HS Code: 2909 49 80

Properties of Methoxy propanol:
Chemical formula: C4H10O2
Molar mass: 90.122 g·mol−1
Appearance: Colorless liquid
Odor: Ethereal
Density: 0.92 g/cm3 (20 °C)
Melting point: −97 °C (−143 °F; 176 K)
Boiling point: 120 °C (248 °F; 393 K)
Solubility in water: Miscible
log P: -0.45

Formula: CH3OCH2CHOHCH3
CAS No: 107-98-2
Molar mass: 90.1 g mol
Density: 0.919 g/cm, liquid
Boiling Point: 120 C
Viscosity: 1.7 cP at 25 C
Other Names: Dowanol PM, 1-Methoxy-2-propanol, Methoxypropanol, Propylene glycol monomethyl ether,

vapor density: 3.12 (vs air)
Quality Level: 200
vapor pressure: 10.9 mmHg ( 25 °C)
product line: ReagentPlus®
Assay: ≥99.5%
form: liquid
autoignition temp.: 532 °F
expl. lim.: 13.8 %

impurities: ≤0.001% water
refractive index: n20/D 1.403 (lit.)
bp: 118-119 °C (lit.)
mp: -97 °C
solubility: water: miscible
density: 0.916 g/mL at 25 °C (lit.)
application(s): microbiology
greener alternative category: Aligned
SMILES string: CC(O)COC
InChI: 1S/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H3
InChI key: ARXJGSRGQADJSQ-UHFFFAOYSA-N

Boiling point: 120 °C (1013 mbar)
Density: 0.921 g/cm3 (25 °C)
Explosion limit: 1.7 - 11.5 %(V)
Flash point: 34 °C
Ignition temperature: 287 °C
Melting Point: -96 °C
pH value: 4 - 7 (200 g/l, H₂O, 20 °C)
Vapor pressure: 11.33 hPa (20 °C)

Molecular Weight: 90.12 g/mol
XLogP3-AA: -0.2
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 2
Exact Mass: 90.068079557 g/mol
Monoisotopic Mass: 90.068079557 g/mol
Topological Polar Surface Area: 29.5Ų
Heavy Atom Count: 6
Complexity: 28.7
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Computed by PubChem (release 2021.05.07)

Specifications of Methoxy propanol:
Purity (GC): ≥ 99.5 %
2-Methoxypropan-1-ol (GC): ≤ 0.29 %
Identity (IR): conforms
Free acid (as C₂H₅COOH): ≤ 0.002 %
Al (Aluminium): ≤ 20 ppb
Ca (Calcium): ≤ 50 ppb
Cu (Copper): ≤ 20 ppb
Fe (Iron): ≤ 100 ppb
K (Potassium): ≤ 50 ppb
Na (Sodium): ≤ 1000 ppb
Ni (Nickel): ≤ 20 ppb
Zn (Zinc): ≤ 20 ppb
Water: ≤ 0.1 %

Related Products of Methoxy propanol:
2,4-Dibromo-6-Fluoro-Benzonitrile
2,2-Dibromo-2-chloroacetamide
(3S)​-3-[[(1,1-Dimethylethoxy)​carbonyl]​amino]​-4-hydroxy-butanoic Acid Methyl Ester
(2Z)-1-(1,1-Dimethylethyl)-2-butenedioic Acid 4-Ethyl Ester
(2Z)-1-(1,1-Dimethylethyl)-2-butenedioic Acid 4-Methyl Ester

Names of Methoxy propanol:

Regulatory process names:
1-Methoxy-2-hydroxypropane
1-METHOXY-2-PROPANOL
1-Methoxy-2-propanol
1-methoxy-2-propanol monopropylene glycol methyl ether
1-methoxy-2-propanol; monopropylene glycol methyl ether
1-methoxypropan-2-ol
1-methoxypropan-2-ol
1-Methoxypropanol-2
2-Methoxy-1-methylethanol
2-Propanol, 1-methoxy-
Closol
Dowanol 33B
Dowtherm 209
Methoxyisopropanol
Methyl proxitol
PGME
Poly-Solve MPM
Propasol solvent M
Propylene glycol 1-methyl ether
Propylene glycol methyl ether
Ucar Solvent LM (Obs.)

Translated names:
1-methoxy-2-propanol monopropylenglycolmethylether (da)
1-Methoxy-2-propanol Monopropylenglycolmethylether (de)
1-methoxypropaan-2-ol propyleenglycolmonomethylether (nl)
1-methoxypropan-2-ol propylenglykolmonomethylether (cs)
1-metoksi-2-propanol monopropilen glikol metil eter (sl)
1-metoksi-2-propanoli monopropyleeniglykolimetyylieetteri (fi)
1-metoksi-2-propanolis monopropilenglikolio metileteris (lt)
1-metoksi-2-propanols monopropilēnglikola metilēteris (lv)
1-metoksy-2-propanol propylenglykolmonometyleter monopropylenglykolmetyleter (no)
1-metoksypropan-2-ol eter monometylowy glikolu propylenowego (pl)
1-metoksü-2-propanool monopropüleenglükoolmetüüleeter (et)
1-metossi-2-propanol eteru tal-metil glikol monopropilen (mt)
1-metossi-2-propanolo propilene glicol mono metil etere (it)
1-metoxi-2-propanol (sv)
1-metoxi-2-propanol monopropilen glicol metil eter (ro)
1-metoxi-2-propanol monopropilén-glikol-metil-éter (hu)
1-metoxi-2-propanol éter metílico de monopropilenglicol (es)
1-metoxi-2-propanol éter monometílico de propilenoglicol (pt)
1-metoxypropán-2-ol monopropylénglykol-metyléter (sk)
1-méthoxy-2-propanol; éther méthylique de monopropylène glycol éther méthylique de monopropylèneglycol (fr)
1-μεθοξυ-προπανόλη-2 μονομεθυλαιθέρας της προπυλενογλυκόλης (el)
1-метокси-2-пропанол монопропилен гликол метил етер (bg)

IUPAC names:
1-METHOXY-2-PROPANOL
1-Methoxy-2-Propanol
1-Methoxy-2-propanol
1-methoxy-2-Propanol
1-methoxy-2-propanol
1-Methoxy-2-propanol
1-Methoxy-2-propanol (Propylene Glycol Methyl Ether)
1-methoxy-2-propanol monopropylene glycol methyl ether
1-Methoxy-2-propanol;
1-Methoxy-2-propanol; 2-Propanol, 1-methoxy-; Closol ...
1-methoxy-2-propanol; monopropylene glycol methyl ether
1-Methoxy-propan-2-ol
1-methoxy-propan-2-ol
1-METHOXYPROPAN-2-OL
1-Methoxypropan-2-ol
1-methoxypropan-2-ol
1-methoxypropan-2-ol
1-methoxypropan-2-ol ... Propylene glycol monomethyl ether
1-Methoxypropanol-2
1-metoksi-2-propanol
1-metoksypropan-2-ol
1-méthoxy-2-propanol
2-propanol, 1-methoxy
2-Propanol, 1-methoxy-
Agent IA94
Dowanol PM
Dowanol PM - TE0036
Glycol Ether PM
Hydrocarbons, C9-C12, n-alkanes, isoalkanes, cyclics, aromatics
Identification: ? 1-methoxy-2-propanol
methoxy propanol
methoxy-1-propanol-2
monopropylene glycol methyl ether
Not available
PM Solvent
propylene glycol methyl ether
Propylene glycol methyl ether
Propylene glycol methyl ether [PGME] (CAS 107-98-2)
Propylene glycol monomethyl ether
Propylene glycol monomethyl ether
propylene glycol monomethylether
Propyleneglycol monomethyl ether
propyleneglycol monomethylether
triphenyl phosphite

Preferred IUPAC name:
1-Methoxypropan-2-ol

Trade names:
1-Methoxy-2-hydroxypropane
1-Methoxy-2-propanol
1-methoxypropan-2-ol
1-Methoxypropanol-2
2-Methoxy-1-methylethanol
2-Propanol, 1-methoxy- (6CI, 7CI, 8CI, 9CI)
Agent IA94
Dowanol TM PM Glycol
DOWANOL™ PM Glycol Ether
Glycol Ether PM
METHYLPROXITOL
MFG
MISSION MODELS POLYURETHANE MIX ADDITIVE
ronacoat ro 304
SHP 401
SOLVENON PM

Other names:
PGME
1-Methoxy-2-propanol
Methoxypropanol
α-Propylene glycol monomethyl ether
Dowanol PM

Other identifiers:
107-98-2
58769-19-0
603-064-00-3

Synonyms of Methoxy propanol:
1-Methoxy-2-propanol
107-98-2
1-Methoxypropan-2-ol
Methoxyisopropanol
PGME
2-Propanol, 1-methoxy-
Closol
Propylene glycol monomethyl ether
Dowtherm 209
1-Methoxy-2-hydroxypropane
Propasol solvent M
Dowanol 33B
PROPYLENE GLYCOL METHYL ETHER
2-Methoxy-1-methylethanol
Methyl proxitol
2-Propanol, methoxy-
Propylene glycol 1-methyl ether
Ucar Solvent LM (Obs.)
NSC 2409
Dowanol-33B
HSDB 1016
1-methoxy-propan-2-ol
EINECS 203-539-1
UN3092
BRN 1731270
UNII-74Z7JO8V3U
.alpha.-Propylene glycol monomethyl ether
AI3-15573
74Z7JO8V3U
Propyleneglycol monomethyl ether
DTXSID8024284
NSC-2409
EC 203-539-1
3-01-00-02146 (Beilstein Handbook Reference)
DTXCID804284
CAS-107-98-2
propyleneglycol monomethylether
Glycol ether pm
Ucar solvent lm
Solvent PM
Icinol PM
methoxy isopropanol
Methoxy-2-propanol
MFCD00004537
1-methoxypropanol-2
1-Metoxipropan-2-ol
1-Metoksy-2-propanol
PME (CHRIS Code)
3-methoxy-propan-2-ol
Propan-1-methoxy-2-ol
2-Propanol, 1-metoxi-
rac-1-methoxy-2-propanol
1- methoxypropan- 2- ol
1,2-PROPYLENE GLYCOL 1-MONOMETHYL ETHER
2-methoxy-1-methyl ethanol
Propan-2-ol, 1-methoxy-
propylene glycol monomethylether
1-Methoxy-2-propanol, 98%
1-Methoxy-2-propanol (PGME)
Methoxypropanol, .alpha. isomer
(+/-)-1-methoxy-2-propanol
1 - methoxypropan - 2 - ol
CHEMBL3186306
METHOXYISOPROPANOL [INCI]
NSC2409
WLN: QY1 & 1O1
propylene glycol mono methyl ether
(+/-)2-methoxy-1-methylethanol
Propylene Glycol 1-Monomethyl Ether
Tox21_201803
Tox21_303269
LS-444
NA3092
1-Methoxy-2-propanol, >=99.5%
AKOS009158246
SB44649
SB44662
NCGC00249123-01
NCGC00256978-01
NCGC00259352-01
Propylene glycol monomethyl ether (PGME)
1-METHOXY-2-HYDROXYPROPANE [HSDB]
1-Methoxy-2-propanol, analytical standard
FT-0608005
FT-0647598
FT-0654880
FT-0655258
M0126
EN300-73396
E72455
PROPYLENE GLYCOL MONOMETHYL ETHER, ALPHA
1-Methoxy-2-propanol [UN3092] [Flammable liquid]
Q1884806
VOC Mixture 614 1.3-930 microg/mL in Triacetin
1-Methoxy-2-propanol [UN3092] [Flammable liquid]
VOC Mixture Kit 664 0.15-930 microg/mL in Triacetin
Z825742124
Propylene glycol monomethyl ether; (UCAR TRIOL HG-170)
Propylene glycol monomethyl ether; (UCAR TRIOL HG-170)
InChI=1/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H
1-Methoxy-2-propanol [ACD/IUPAC Name]
107-98-2 [RN]
1-Methoxy-2-hydroxypropane
1-Methoxy-2-propanol [German] [ACD/IUPAC Name]
1-Méthoxy-2-propanol [French] [ACD/IUPAC Name]
1-methoxypropan-2-ol
203-539-1 [EINECS]
2-Propanol, 1-methoxy- [ACD/Index Name]
74Z7JO8V3U
DOWANOL(R) PM
Methoxyisopropanol
Propylene glycol methyl ether [Wiki]
Propylene glycol monomethyl ether
Propyleneglycol monomethyl ether
UB7700000
UN 3092
UNII:74Z7JO8V3U
(R)-1-Methoxypropan-2-ol
(R)-tert-butyl 3-formylpiperidine-1-carboxylate
(S)-1-Methoxypropan-2-ol
1,2-propylene glycol 1-monomethyl ether
2-Methoxy-1-methylethanol
2-Propanol, methoxy-
Closol [Trade name]
Dowanol 33B [Trade name]
Dowanol PM [Trade name]
Dowanol-33B [Trade name]
Dowtherm 209 [Trade name]
Icinol PM [Trade name]
methoxypropanol
Methoxypropanol, α isomer
Methyl proxitol
MFCD01632587 [MDL number]
MFCD01632588 [MDL number]
PGME
Propan-1-methoxy-2-ol
propan-2-ol, 1-methoxy-
Propasol solvent M [Trade name]
Propylene glycol 1-methyl ether
Propylenglykol-monomethylaether [German]
QY1 & 1O1 [WLN]
Solvent PM [Trade name]
ucar solvent LM [Trade name]
α-Propylene glycol monomethyl ether
méthoxyisopropanol ( Éther monométhylique de propylène glycol )
3-Methoxy-3-methyl-1-butanol; 3-methoxy-3-methylbutan-1-ol; 1-Butanol, 3-methoxy-3-methyl-; 3-Methyl-3-methoxybutanol CAS NO:56539-66-3
Methoxymethyl butanol (MMB)
METHOXYMETHYLBUTANOL, N° CAS : 56539-66-3, 3-méthoxy-3-méthylbutane-1-ol . Nom INCI : METHOXYMETHYLBUTANOL. Nom chimique : 1-Butanol, 3-methoxy-3-methyl-, N° EINECS/ELINCS : 260-252-4. Ses fonctions (INCI) : Solvant : Dissout d'autres substances
METHOXYMETHYLBUTANOL
3-Methoxypropylamine (MOPA); 3-Aminopropyl methyl ether, 3-Methoxy-1-propanamine, 1-Amino-3-methoxypropane, 3-Methoxy-n-propylaminl CAS: 5332-73-0
methoxyphenyl t-butylphenyl propanedio
1-(4-tert-Butyl-phenyl)-3-(4-methoxy-phenyl)-propane-1,3-diol,RonaCare Pristine Bright;1-(4-tert-Butylphenyl)-3-(4-methoxyphenyl)-1,3-propanediol; 1-(4-(tert-Butyl)phenyl)-3-(4-methoxyphenyl)propane-1,3-diol CAS NO:955359-35-0
METHOXYPOLYETHYLENE GLYCOL 350
Methoxypolyethylene glycol 350 is a polymer similar in structure and nomenclature to polyethylene glycols.
Methoxypolyethylene glycol 350 is a Polyethylene glycol (PEG) macromer with a reactive chain end consisting of methyl ether.
Methoxypolyethylene glycol 350 is a PEG linker containing a hydroxyl group.

CAS number: 9004-74-4
Molecular Formula: C5H12O3
Molecular Weight: 120.14698
EINECS Number: 618-394-3

Peg-7 methyl ether, ENK4Y6S66X, MARLIPAL 1/7, METHOXY PEG-7, METHOXYPOLYETHYLENE GLYCOL 350, METHOXYPOLYOXYETHYLENE GLYCOL 350, MPEG 350 ,MPEG-7, PEG-7 METHYL ETHER (II), POLYETHYLENE GLYCOL (7) METHYL ETHER, POLYETHYLENE GLYCOL 350 METHYL ETHER, POLYXOYETHYLENE (7) METHYL ETHER,Polyoxyethylene Monomethyl Ether, Poly(Ethylene Oxide) Methyl Ether, Poly(Ethylene Oxide) Monomethyl Ether,α-Methyl-ω-hydroxypoly(oxy-1,2-ethanediyl).

Methoxypolyethylene glycol 350 is a polymer similar in structure and nomenclature to polyethylene glycols.
Methoxypolyethylene glycol 350 is a type of polyethylene glycol (PEG) that is chemically modified with methoxy groups.
Methoxypolyethylene glycol 350 are a family of water-soluble polymers composed of repeating units of ethylene oxide.

The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
The hydrophilic Methoxypolyethylene glycol 350 spacer increases solubility in aqueous media.
Etherification of the Methoxypolyethylene glycol 350 chain ends can be undertaken in basic conditions by reacting it with alkyl halides.

Methoxypolyethylene glycol 350 can undergo cross linking to form hydrogels; polymerization can be initiated by redox reaction or free radical initiator.
The number following the "PEG" designation indicates the average molecular weight of the polymer.

In the case of Methoxypolyethylene glycol 350, it signifies an average molecular weight around 350 grams per mole.
Methoxypolyethylene glycol 350 is a polymer similar in structure and nomenclature to polyethylene glycols.

Methoxypolyethylene glycol 350 belongs to the category of Intermediates and is used as a reference standard in research.
Methoxypolyethylene glycol 350 that provides enhanced solvency, lubricity, hygroscopicity and with slightly more hydrophobic solvent properties.
Methoxypolyethylene glycol 350 of with an average molecular mass of 350.

Methoxypolyethylene glycol 350 is used in various applications such as micelles for drug delivery as well as in modifications of therapeutic proteins to improve their pharmacokinetics.
Methoxypolyethylene glycol 350ls are addition polymers of ethylene oxide and methanol, represented by the generalised formula CH3O- (CH2-CH2-O)n-H, with Œn¹ indicating the average number of oxyethylene groups.
In chemical abstracts methoxy polyethylene glycols are described under the scientific name Poly(oxy-1,2-ethanediyl)-a-methyl-whydroxy in combination with the CAS register number 9004-74-4.

Other names are polyethylene glycol monomethyl ether and Methoxypolyethylene glycol 350.
Methoxy polyethylene glycols are available in average molecular weights ranging from 350 to 5000.
Methoxypolyethylene glycol 350 is a polymer with the chemical formula HO(CH2CH2O)nH.

Methoxypolyethylene glycol 350 is properties vary according to its molecular weight, from a colourless and odourless viscous liquid to a waxy solid.
Methoxypolyethylene glycol 350 is a liquid at room temperature with a molecular weight of 200 to 600, and gradually becomes a semi-solid with a molecular weight above 600, with different properties depending on the average molecular weight.
From colourless and odourless viscous liquids to waxy solids.

As the molecular weight increases, Methoxypolyethylene glycol 350 is hygroscopic capacity decreases accordingly.
Methoxypolyethylene glycol 350 is soluble in water, ethanol and many other organic solvents.
Methoxypolyethylene glycol 350 has a low vapour pressure and is stable to heat, acids and bases.

Methoxypolyethylene glycol 350 does not interact with many chemicals.
Methoxypolyethylene glycol 350 has good hygroscopicity, lubricity and bonding properties.
Methoxypolyethylene glycol 350 are designated by a number indicating the average molecular weight.

Methoxypolyethylene glycol 350 and 500 are clear viscous liquids at room temperature but Methoxypolyethylene glycol 750 and 1000 require a temperature above 40°C.
Methoxypolyethylene glycol 350 2000, 3000 and 5000 are white waxy solids that are supplied in flake form.
Some grades may also be supplied in molten form.

For special product demands, information on applications or other special requirements contact the local sales office.
All Methoxypolyethylene glycol 350s are soluble in many polar solvents as aliphatic ketones, alcohols, glycol ethers, esters and aromatic hydrocarbons.
Methoxypolyethylene glycol 350s are readily miscible with water, the solid Methoxypolyethylene glycol 350s are slightly less soluble in water with their solubility decreasing as molecular weight increases.

Methoxypolyethylene glycol 350s are addition polymers of ethylene oxide and methanol, represented by the generalised formula CH3O-(CH2-CH2-O)n-H, with Œn¹ indicating the average number of oxyethylene groups.
In chemical abstracts Methoxypolyethylene glycol 350s are described under the scientific name Poly(oxy-1,2-ethanediyl)-a-methyl-w-hydroxy in combination with the CAS register number 9004-74-4.
Other names are polyethylene glycol monomethyl ether and Methoxypolyethylene glycol 350.

Methoxypolyethylene glycol 350s are available in average molecular weights ranging from 350 to 5000.
Methoxypolyethylene glycol 350 is designated by a number indicating the average molecular weight.

Methoxypolyethylene glycol 350 (average mol wt 350) is a versatile compound used in various research and industrial applications.
Methoxypolyethylene glycol 350 offers great chemical stability and compatibility with different solvents
Methoxypolyethylene glycol 350 is a hydroxyether that is ethanol substituted by a methoxy group at position 2.

Methoxypolyethylene glycol 350 has a role as a protic solvent and a solvent.
Methoxypolyethylene glycol 350 by Dow is PEG-6 methyl ether-based plasticizer.
Methoxypolyethylene glycol 350 maintains wet-tack strength and possesses lubricity and humectant properties.

Methoxypolyethylene glycol 350 appears as a clear colorless liquid.
Methoxypolyethylene glycol 350's flash point of 110 °F.
Methoxypolyethylene glycol 350 is white granular.

Soluble in water, soluble in some organic solvents.
Methoxypolyethylene glycol 350 is solution has high viscosity at low concentration, and can be processed by calendering, extrusion, casting, etc.
Methoxypolyethylene glycol 350 is a thermoplastic resin with good compatibility with other resins.

Methoxypolyethylene glycol 350 is resistant to bacterial erosion and has weak hygroscopicity in the atmosphere.
Methoxypolyethylene glycol 350 is less dense than water.
Methoxypolyethylene glycol 350's vapors are heavier than air.

Methoxypolyethylene glycol 350 that provides enhanced solvency, lubricity, hygroscopicity and with slightly more hydrophobic solvent properties.
For use in soaps and detergents, adhesives, chemical Intermediates, inks and dye carrier, lubricants, and plasticizer.
Methoxypolyethylene glycol 350 is a polyether compound with the structure derived from ethylene oxide monomers, and it contains methoxy (-OCH3) groups attached to the ethylene glycol backbone.

Like other PEGs, Methoxypolyethylene glycol 350 is highly soluble in water and other polar solvents.
This characteristic makes it useful in various formulations where water solubility is essential.
Methoxypolyethylene glycol 350 is commonly used in pharmaceutical formulations, including as a component in drug delivery systems, solubilizing agents, and in topical preparations.

Methoxypolyethylene glycol 350 can be found in cosmetic and personal care products, such as creams, lotions, and hair care products, where it may function as a moisturizer or emollient.
Methoxypolyethylene glycol 350 can be employed in various industrial applications, such as in the formulation of certain lubricants, coatings, and as a component in chemical processes.
Methoxypolyethylene glycol 350, are known for their biocompatibility, low toxicity, and the ability to modify the physical and chemical properties of substances when incorporated into formulations.

Methoxypolyethylene glycol 350 is often used as a solubilizing agent for poorly water-soluble substances, enhancing the bioavailability of certain drugs.
Methoxypolyethylene glycol 350 is use in pharmaceuticals extends to drug delivery systems, where it can contribute to the controlled release of active ingredients.
Methoxypolyethylene glycol 350s are hygroscopic, meaning they have a tendency to absorb moisture from the surroundings.

This property can impact the stability and appearance of formulations.
Methoxypolyethylene glycol 350 has a white flakes form.
Methoxypolyethylene glycol 350 is used in various applications such as micelles for drug delivery as well as in modifications of therapeutic proteins to improve their pharmacokinetics.

Methoxypolyethylene glycol 350 has been used in a study to assess the synthesis of a new class of thermosensitive micellar cyclotriphosphazenes.
Methoxypolyethylene glycol 350 has also been used in a study to investigate synthesis of a new amphiphilic poly(organophosphazene) by stepwise nucleophilic substitution.
Methoxypolyethylene glycol 350 is a Polyethylene glycol (PEG) macromer with a reactive chain end consisting of methyl ether.

Etherification of the Methoxypolyethylene glycol 350 chain ends can be undertaken in basic conditions by reacting it with alkyl halides.
Methoxypolyethylene glycol 350 can undergo cross linking to form hydrogels; polymerization can be initiated by redox reaction or free radical initiator.
Methoxypolyethylene glycol 350 has been used in a study to assess the synthesis of a new class of thermosensitive micellar cyclotriphosphazenes.

Methoxypolyethylene glycol 350 has also been used in a study to investigate synthesis of a new amphiphilic poly(organophosphazene) by stepwise nucleophilic substitution.
Methoxypolyethylene glycol 350 is a polymer similar in structure and nomenclature to polyethylene glycols.
Methoxypolyethylene glycol 350 is PEG-6 methyl ether-based plasticizer.

Methoxypolyethylene glycol 350 maintains wet-tack strength and possesses lubricity and humectant properties.
Methoxypolyethylene glycol 350 is used in pressure-sensitive and thermoplastic adhesives.
Methoxypolyethylene glycol 350 is soluble in many polar solvents as aliphatic ketones, alcohols, glycol ethers, esters and aromatic hydrocarbons.

Methoxypolyethylene glycol 350 is readily miscible with water.
Methoxypolyethylene glycol 350 is slightly less soluble in water with their solubility decreasing as molecular weight increases.
Methoxypolyethylene glycol 350 is a long chain methacrylate monoester based on an ethylene oxide backbone.

Methoxypolyethylene glycol 350 is water soluble and contains approximately 8 ethylene oxide (EO) units in the chain.
Methoxypolyethylene glycol 350, or methyl cellosolve, is an organic compound with formula C3H8O2 that is used mainly as a solvent.
Methoxypolyethylene glycol 350 is a clear, colorless liquid with an ether-like odor.

Lipid Methoxypolyethylene glycol 350, also known as polyethylene glycolated lipids, are PEG derivatives containing lipid molecules such as DSPE that have been used for bioadhesive and lipid nanoparticle (LNP) drug delivery to improve the cycle time of liposomal encapsulated drugs.
Lipid molecules are low toxic and easy to prepare, and can be used as carriers not only for water-soluble drugs but also for lipid-soluble drugs.
Therefore, Methoxypolyethylene glycol 350 lipids can be used to improve drug stability, multiple routes of drug delivery, and enable targeted drug delivery.

Methoxypolyethylene glycol 350 is in a class of solvents known as glycol ethers which are notable for their ability to dissolve a variety of different types of chemical compounds and for their miscibility with water and other solvents.
Methoxypolyethylene glycol 350 can be formed by the nucleophilic attack of methanol on protonated ethylene oxide followed by proton transfer: C2H5O++ CH3OH → C3H8O2 + H+
Methoxypolyethylene glycol 350 is a hydroxyether that is ethanol substituted by a methoxy group at position 2.

Methoxypolyethylene glycol 350 has a role as a protic solvent and a solvent.
Methoxypolyethylene glycol 350 appears as a clear colorless liquid.
Methoxypolyethylene glycol 350 is less dense than water.

Melting point: 60-64 °C
Boiling point: >200°C/760mmHg
Density: 1.094 g/mL at 25 °C
vapor density: >1 (vs air)
vapor pressure: 0.05 mm Hg ( 20 °C)
refractive index: n20/D 1.459
Flash point: 268 °C
storage temp.: -20°C
solubility: H2O: 50 mg/mL at 25 °C, clear, colorless
form: semisolid
Specific Gravity: 1.094
color: White to pale yellow
PH: 5.5-7.0 (25℃, 50mg/mL in H2O)
Water Solubility: Slightly miscible with water.
λmax: λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03
Stability: Stable. Incompatible with strong oxidizing agents, strong acids, strong bases.
InChIKey: XNWFRZJHXBZDAG-UHFFFAOYSA-N
LogP: -0.800 (est)

Methoxypolyethylene glycol 350 is sold as a liquidand can be stored inside a warm building without provision for heating.
If storage time is prolonged orif tank is heated or in a hot climate, Methoxypolyethylene glycol 350 is preferable to store this product under a nitrogen atmosphere.
If heated storage is required, metal temperature should not exceed 50°C.

Methoxypolyethylene glycol 350 that provides enhanced solvency, lubricity, hygroscopicity and with slightly more hydrophobic solvent properties.
Methoxypolyethylene glycol 350 is used in lubricants and plasticizer.
Methoxypolyethylene glycol 350 has a viscous liquid to white flakes form.

Methoxypolyethylene glycol 350 is used for drug delivery.
Methoxypolyethylene glycol 350, like other polyethylene glycols, is highly hydrophilic, meaning it has an affinity for water.
This property is beneficial in formulations where water solubility and hydration are desired.

PEGs, including Methoxypolyethylene glycol 350, can act as surfactants.
Surfactants have the ability to reduce surface tension, and they are often used in formulations to enhance the spreading and wetting properties of products like creams and lotions.
Methoxypolyethylene glycol 350 can function as an emulsifying agent, helping to stabilize oil-in-water emulsions.

This is particularly useful in the formulation of cosmetic and pharmaceutical products that contain both oil and water components.
Methoxypolyethylene glycol 350s are commonly used as a part of polymer structures in drug delivery systems.
The hydrophilic nature of Methoxypolyethylene glycol 350 can improve the solubility of the carrier and enhance the circulation time of drug-loaded nanoparticles or micelles in the bloodstream.

In pharmaceutical applications, Methoxypolyethylene glycol 350 is often employed to enhance the bioavailability of poorly water-soluble drugs by improving their solubility and dissolution rate.
Methoxypolyethylene glycol 350 is synthesized through the reaction of ethylene oxide with methanol, and the resulting product is then characterized by its average molecular weight.
Methoxypolyethylene glycol 350, are known for their biocompatibility, low immunogenicity, and minimal toxicity.

These characteristics contribute to their use in various biomedical and pharmaceutical applications.
Methoxypolyethylene glycol 350 is crucial in pharmaceutical and cosmetic applications.
Methoxypolyethylene glycol 350's important to ensure that the manufacturing process and quality control measures meet industry standards.

The use of Methoxypolyethylene glycol 350 in pharmaceuticals and cosmetics is subject to regulatory guidelines.
Manufacturers must comply with safety and quality standards to ensure consumer safety.
The stability of formulations containing Methoxypolyethylene glycol 350 can be influenced by factors such as temperature, pH, and exposure to light.

Proper storage conditions are essential to maintain the stability of products over time.
Methoxypolyethylene glycol 350 is part of a family of polyethylene glycol derivatives that includes various PEGs with different molecular weights, allowing for versatility in different applications.
Methoxypolyethylene glycol 350 is a macromer with a reactive chain end consisting of methyl ether.

Methoxypolyethylene glycol 350 has also been used in a study to investigate synthesis of a new amphiphilic poly(organophosphazene) by stepwise nucleophilic substitution.
Methoxypolyethylene glycol 350 is soluble in many polar solvents as aliphatic ketones, alcohols, glycol ethers, esters and aromatic hydrocarbons.
Methoxypolyethylene glycol 350 is readily miscible with water.

Methoxypolyethylene glycol 350 is a long chain methacrylate monoester based on an ethylene oxide backbone.
Methoxypolyethylene glycol 350 is used as a solvent for many different purposes such as varnishes, dyes, and resins.
Methoxypolyethylene glycol 350 is a Polyethylene glycol (PEG) macromer with a reactive chain end consisting of methyl ether.

Methoxypolyethylene glycol 350 chain ends can be undertaken in basic conditions by reacting it with alkyl halides.
Methoxypolyethylene glycol 350 can undergo cross linking to form hydrogels; polymerization can be initiated by redox reaction or free radical initiator.
Methoxypolyethylene glycol 350 is known for its potential to enhance the dermal absorption of certain substances.

In cosmetic and pharmaceutical formulations, this property can influence the delivery of active ingredients through the skin.
Methoxypolyethylene glycol 350, are generally considered biodegradable.
They can be broken down by microorganisms over time, contributing to their environmental compatibility.

Methoxypolyethylene glycol 350 is sometimes used as a component in the formation of polymeric nanoparticles, micelles, or liposomes for drug delivery applications.
Certain PEG-based polymers, including those derived from Methoxypolyethylene glycol 350, can exhibit thermosensitive behavior.
This property can be exploited in drug delivery systems that respond to changes in temperature.

Methoxypolyethylene glycol 350 is generally chemically stable under normal storage conditions.
However, exposure to extreme temperatures or harsh conditions may impact its stability, and formulations should be stored appropriately.
Methoxypolyethylene glycol 350, the process of attaching polyethylene glycol chains to molecules such as proteins or peptides, is a strategy used to improve the pharmacokinetics and reduce immunogenicity of therapeutic agents.

Methoxypolyethylene glycol 350 may be used for this purpose in certain pharmaceutical formulations.
Methoxypolyethylene glycol 350 exhibits good compatibility with a wide range of formulation ingredients.
This versatility allows its use in diverse applications across different industries.

Methoxypolyethylene glycol 350s are generally considered safe, individuals with sensitive skin may experience irritation from products containing Methoxypolyethylene glycol 350.
Methoxypolyethylene glycol 350's important for manufacturers to conduct skin compatibility testing and provide appropriate warnings on product labels.
Methoxypolyethylene glycol 350 can impact the rheological (flow and deformation) properties of formulations.

This can be beneficial in achieving desired textures and application characteristics in products such as creams and gels.
Methoxypolyethylene glycol 350, there are other polyethylene glycol variants with different molecular weights, such as PEG-400, PEG-600, etc.
Each variant may have specific applications based on its molecular characteristics.

Methoxypolyethylene glycol 350, are used in protein formulations to enhance stability, reduce aggregation, and prevent denaturation.
This is particularly relevant in the pharmaceutical and biotechnology industries.
Manufacturers may offer custom synthesis of Methoxypolyethylene glycol 350 to meet specific requirements of formulation scientists and researchers working on unique applications.

Methoxypolyethylene glycol 350 is used in various applications such as micelles for drug delivery as well as in modifications of therapeutic proteins to improve their pharmacokinetics.
Methoxypolyethylene glycol 350 has been used in a study to assess the synthesis of a new class of thermosensitive micellar cyclotriphosphazenes.
Methoxypolyethylene glycol 350 has also been used in a study to investigate synthesis of a new amphiphilic poly(organophosphazene) by stepwise nucleophilic substitution.

Methoxypolyethylene glycol 350 is the main material for producing water reducing agent of polycarboxylate high effective cement.
With well water-solubility, wettability, lubricity, physiologically inert characteristics, incitingless and moderate characteristics, Methoxypolyethylene glycol 350 is widely used in cosmetics and pharmaceutical industry.

Uses:
Methoxypolyethylene glycol 350 has been used in a study to assess the synthesis of a new class of thermosensitive micellar cyclotriphosphazenes.
Methoxypolyethylene glycol 350 has also been used in a study to investigate synthesis of a new amphiphilic poly(organophosphazene) by stepwise nucleophilic substitution.
Methoxypolyethylene glycol 350 is used in various applications such as micelles for drug delivery as well as in modifications of therapeutic proteins to improve their pharmacokinetics.

Methoxypolyethylene glycol 350 has been used in a study to assess the synthesis of a new class of thermosensitive micellar cyclotriphosphazenes.
Methoxypolyethylene glycol 350 has also been used in a study to investigate synthesis of a new amphiphilic poly(organophosphazene) by stepwise nucleophilic substitution.
Methoxypolyethylene glycol 350 is used in various applications such as micelles for drug delivery as well as in modifications of therapeutic proteins to improve their pharmacokinetics.

Methoxypolyethylene glycol 350 has been used in a study to assess the synthesis of a new class of thermosensitive micellar cyclotriphosphazenes.
Methoxypolyethylene glycol 350 has also been used in a study to investigate synthesis of a new amphiphilic poly(organophosphazene) by stepwise nucleophilic substitution.
Methoxypolyethylene glycol 350 can be used as a medium for organic synthesis and a heat carrier with high requirements.

Methoxypolyethylene glycol 350 is used as a humectant, inorganic salt solubilizer and viscosity adjuster in the daily chemical industry; as a softener and antistatic agent in the textile industry; as a wetting agent in the paper and pesticide industry.
Methoxypolyethylene glycol 350 is most suitable for softgels.
Methoxypolyethylene glycol 350 is a liquid, it has a wide range of compatibility with various solvents and is a good solvent and solubiliser, and is widely used in liquid formulations, such as oral liquids and eye drops.

Methoxypolyethylene glycol 350 is the material of choice when vegetable oils are not suitable as a carrier for active ingredients.
Methoxypolyethylene glycol 350 is used as a base or lubricant and softener in the pharmaceutical, textile and cosmetic industries; used as a dispersant in the paint industry to improve the water dispersibility and flexibility of resins, with a dosage of 10-30%; used to improve the solubility of dyestuffs and reduce their volatility in printing ink, especially in wax paper and printing ink, also used to adjust the consistency of ink in biros ink.

Methoxypolyethylene glycol 350 is also used as a dispersant in the rubber industry to promote vulcanisation and as a dispersant for carbon black filling materials.
Methoxypolyethylene glycol 350 is used as metal processing casting agent, lubricant and cutting fluid for metal drawing, stamping or forming, grinding cooling lubricating polishing agent, welding agent, etc.; used as lubricant in paper industry, etc., also used as hot melt adhesive to increase fast rewetting ability.
Methoxypolyethylene glycol 350 good coating material, hydrophilic polishing material, film and capsule material, plasticizer, lubricant and drip matrix for the preparation of tablets, pills, capsules, microcapsules, etc.

Methoxypolyethylene glycol 350 is used as a finishing agent in the paper industry to increase the gloss and smoothness of paper; as an additive in the rubber industry to increase the lubricity and plasticity of rubber products, reduce the power consumption during processing and extend the service life of rubber products.
In the field of gene therapy, Methoxypolyethylene glycol 350 may be utilized in the development of gene delivery systems, where it helps improve the stability and efficiency of delivering genetic material.
Methoxypolyethylene glycol 350 can be used in the development of biocompatible coatings for biomedical devices, helping to reduce the risk of adverse reactions when these devices come into contact with biological tissues.

In marine coatings, Methoxypolyethylene glycol 350 may contribute to the formulation of antifouling coatings, helping to prevent the attachment of marine organisms to ship hulls and underwater structures.
In oral drug formulations, Methoxypolyethylene glycol 350 may be used to create hydrophilic matrices, which can influence drug release characteristics and enhance bioavailability.
Dental Products:
Methoxypolyethylene glycol 350 might be included in dental products such as toothpaste or oral rinses for its solubilizing and emulsifying properties.

Methoxypolyethylene glycol 350 can be part of lipid nanoparticle formulations used in the delivery of mRNA vaccines, contributing to the stability and effectiveness of the vaccine.
Methoxypolyethylene glycol 350 may be involved in microencapsulation processes, providing a protective coating for active ingredients in pharmaceuticals or food products.
Methoxypolyethylene glycol 350 may be used in the formulation of reagents for in vitro diagnostics, contributing to the stability and functionality of diagnostic assays.

In sensor development, Methoxypolyethylene glycol 350 can be part of polymer-based sensor formulations, influencing properties such as sensitivity and selectivity.
In materials science, Methoxypolyethylene glycol 350 can be blended with other polymers to create materials with unique hydrophilic properties.
Methoxypolyethylene glycol 350 may be included in certain detergent formulations, contributing to the solubility and stability of cleaning agents.

In the pharmaceutical industry, Methoxypolyethylene glycol 350 can be involved in the development of inhalable drug delivery systems for respiratory medications.
Methoxypolyethylene glycol 350 may be used as a dispersant in the formulation of paints and coatings, contributing to the even distribution of pigments.
Methoxypolyethylene glycol 350 can be used for surface modification of materials to alter their properties, such as wettability or adhesion.

Methoxypolyethylene glycol 350 can be part of lubricants or coatings, providing hydrophilic properties and enhancing device performance.
Methoxypolyethylene glycol 350 may be used in grafting reactions to modify the properties of other polymers.
In the formulation of certain food and beverage products, Methoxypolyethylene glycol 350 may contribute to the creation of stable nanoemulsions.

Methoxypolyethylene glycol 350 is often employed in the formulation of drug delivery systems, particularly in the creation of micelles or nanoparticles that can encapsulate and deliver pharmaceutical compounds.
This can improve the solubility and bioavailability of certain drugs.
Methoxypolyethylene glycol 350 may be used for PEGylation, a process of attaching polyethylene glycol chains to therapeutic agents, to enhance their stability, reduce immunogenicity, and prolong their circulation time in the body.

Methoxypolyethylene glycol 350 can be found in skincare products such as creams and lotions, where it may act as a moisturizer or emollient.
Methoxypolyethylene glycol 350 may be included in formulations for hair care products, contributing to their texture and feel.
Methoxypolyethylene glycol 350 can be used in the formulation of certain lubricants and coatings.

Methoxypolyethylene glycol 350 may be used as a component in various industrial chemical processes.
Methoxypolyethylene glycol 350 or similar PEG derivatives may find use as food additives, particularly in formulations where water solubility is beneficial.
Methoxypolyethylene glycol 350 is used in the creation of nanoparticles for research purposes, especially in the development of novel drug delivery systems.

Methoxypolyethylene glycol 350 may be used in products designed to preserve the freshness and appearance of flowers.
Methoxypolyethylene glycol 350 can be incorporated into certain industrial cleaning products, contributing to their formulation.
In the textile industry, Methoxypolyethylene glycol 350 may be used as a component in dyeing processes or formulations.

Methoxypolyethylene glycol 350 is used in the formulation of certain photographic chemicals.
Methoxypolyethylene glycol 350 can be used as a flame retardant in certain plastic formulations.
In the conservation of art and historical artifacts, Methoxypolyethylene glycol 350 may find application in certain formulations.

In some formulations, Methoxypolyethylene glycol 350 may be included as part of insect repellent products.
Methoxypolyethylene glycol 350 can function as an emulsion stabilizer, contributing to the stability of oil-in-water emulsions in various formulations.
Methoxypolyethylene glycol 350 acts as a surfactant, helping to reduce the surface tension of liquids and improve the dispersibility of substances.

In the field of nanomedicine, Methoxypolyethylene glycol 350 may be used in the preparation of polymeric nanoparticles for drug delivery applications, where the controlled release of pharmaceuticals is desired.
Methoxypolyethylene glycol 350 can be used in the coating of medical devices, providing a hydrophilic surface that helps in the prevention of biofouling and improves biocompatibility.
Methoxypolyethylene glycol 350 may be used for the stabilization of enzymes, maintaining their activity and prolonging their lifespan.

Methoxypolyethylene glycol 350 can be part of formulations that involve liquid crystals, which have applications in areas like display technologies and drug delivery.
In the polymer industry, Methoxypolyethylene glycol 350 can be used in blends and composites to modify the physical and chemical properties of polymers.
Methoxypolyethylene glycol 350 may be involved in the creation of thermo-responsive hydrogels, which have applications in drug delivery and tissue engineering.

In the development of contrast agents for biomedical imaging, Methoxypolyethylene glycol 350 may be part of formulations designed for specific imaging modalities.
In tissue engineering, Methoxypolyethylene glycol 350 can contribute to the development of scaffolds or matrices that mimic the extracellular environment, supporting cell growth and tissue formation.
Methoxypolyethylene glycol 350 may be utilized in the formulation of sustained-release dosage forms, providing a controlled release of active pharmaceutical ingredients over an extended period.

In the development of hydrogel dressings for wound care, Methoxypolyethylene glycol 350 can be part of formulations that promote moisture retention and tissue healing.
As a component in biodegradable polymers, Methoxypolyethylene glycol 350 may contribute to the development of environmentally friendly materials.
Methoxypolyethylene glycol 350 can be used in the formulation of pharmaceutical and healthcare products for veterinary applications.

In the formulation of certain industrial adhesives and sealants, Methoxypolyethylene glycol 350 may contribute to desired properties.
Methoxypolyethylene glycol 350 is used in various research and development activities, including the synthesis of new materials and the investigation of novel formulations.

Safety Profile:
Undiluted Methoxypolyethylene glycol 350 may cause irritation to the skin and eyes.
Direct contact with the skin or eyes should be avoided, and if contact occurs, it should be promptly washed with water.
Some individuals may be sensitive or allergic to certain polyethylene glycols, including Methoxypolyethylene glycol 350.

Skin patch testing is recommended, especially in cosmetic and personal care products where skin contact is likely.
Inhalation of aerosols or vapors of Methoxypolyethylene glycol 350 should be minimized, especially in industrial settings.
Adequate ventilation is important to reduce the risk of inhalation exposure.

While ingestion is not a typical route of exposure, accidental swallowing of products containing Methoxypolyethylene glycol 350 should be avoided.
Ingestion can lead to gastrointestinal irritation.

Methoxypolyethylene glycol 350s are generally considered biodegradable, large-scale releases into the environment can have ecological consequences.
Methoxypolyethylene glycol 350 is important to handle and dispose of products containing Methoxypolyethylene glycol 350 in accordance with environmental regulations.

METHOXYPOLYETHYLENE GLYCOL 350

Methoxypolyethylene glycol 350, also known as MPEG-350, is a chemical compound belonging to the class of polyethylene glycols (PEGs).
PEGs are polymers composed of repeating ethylene oxide units. MPEG-350 specifically has an average molecular weight around 350 Daltons.

CAS Number: 9004-74-4
EC Number: 618-394-3

Synonyms: MPEG-350, MethoxyPEG-350, Polyethylene glycol monomethyl ether 350, Methoxy polyoxyethylene glycol 350, Methoxypoly(ethylene glycol) 350, Methoxy-poly(ethylene oxide) 350, PEG methyl ether 350, Methoxy-polyethylene oxide 350, Polyethylene glycol methyl ether 350, MPEG350, Methoxypolyethylene oxide 350, Methoxypolyoxyethylene glycol 350, Poly(ethylene glycol) methyl ether 350, MethoxyPEG 350, Methoxy-polyethylene glycol 350, Methoxypoly(ethylene oxide) 350, Methoxypolyethylene oxide 350, PEG monomethyl ether 350, Methoxypolyoxyethylene glycol 350, Polyethylene oxide methyl ether 350, Methoxy PEG 350, Methoxy polyethylene glycol 350, Methoxy-poly(ethylene glycol) 350, Methoxy polyethylene oxide 350, Methoxy polyoxyethylene glycol 350, Polyethylene glycol methyl ether 350, Methoxypolyethylene glycol monomethyl ether 350, Polyethylene glycol monomethyl ether 350, Methoxy polyethylene glycol monomethyl ether 350, MPEG 350, MethoxyPEG-350, Methoxypolyethylene glycol 3500, MPEG-3500, MethoxyPEG-3500, Polyethylene glycol monomethyl ether 3500, Methoxy polyoxyethylene glycol 3500, Methoxypoly(ethylene glycol) 3500, Methoxy-poly(ethylene oxide) 3500, PEG methyl ether 3500, Methoxy-polyethylene oxide 3500, Polyethylene glycol methyl ether 3500



APPLICATIONS


Methoxypolyethylene glycol 350 is extensively utilized as a solubilizing agent in pharmaceutical formulations.
Methoxypolyethylene glycol 350 is commonly employed in the preparation of oral solutions and suspensions to enhance drug solubility.

Methoxypolyethylene glycol 350 serves as an effective emulsifier in the formulation of creams, lotions, and ointments.
In cosmetics, it is used to stabilize emulsions and improve the texture of skincare products.
Methoxypolyethylene glycol 350 is a key component in the production of transdermal patches for controlled drug delivery.

Methoxypolyethylene glycol 350 finds application in the formulation of eye drops and ophthalmic solutions to improve drug bioavailability.
Methoxypolyethylene glycol 350 is utilized as a lubricant in various mechanical systems to reduce friction and wear.

Methoxypolyethylene glycol 350 is employed in the manufacture of lubricating gels and fluids for medical devices and equipment.
Methoxypolyethylene glycol 350 is utilized as a dispersing agent in the preparation of pigment dispersions and coatings.

In the food industry, it is used as an additive in food processing to improve texture and stability.
Methoxypolyethylene glycol 350 is employed in the production of printing inks and adhesives for its binding properties.

Methoxypolyethylene glycol 350 serves as a plasticizer in the fabrication of polymer films, membranes, and coatings.
Methoxypolyethylene glycol 350 is utilized as a flotation agent in mineral processing to separate minerals from ores.

Methoxypolyethylene glycol 350 is employed in the synthesis of specialty chemicals and polymers as a reactive intermediate.
Methoxypolyethylene glycol 350 finds application in the formulation of crop protection products such as herbicides and pesticides.

Methoxypolyethylene glycol 350 is utilized in the preparation of dental materials such as impression materials and dental adhesives.
Methoxypolyethylene glycol 350 is employed in the formulation of inkjet printing inks for its dispersing and wetting properties.
In the textile industry, it is used as a softener and finishing agent for fabrics and textiles.
Methoxypolyethylene glycol 350 is utilized in the production of detergents and cleaning products for its surfactant properties.

Methoxypolyethylene glycol 350 finds application in the synthesis of specialty polymers and hydrogels for biomedical and tissue engineering applications.
Methoxypolyethylene glycol 350 is utilized in the formulation of veterinary medicines and animal healthcare products.

Methoxypolyethylene glycol 350 is employed in the preparation of diagnostic reagents and assays for biochemical and medical testing.
Methoxypolyethylene glycol 350 is utilized in the production of personal care products such as shampoos and conditioners.
It finds application in the formulation of ink formulations for fountain pens and writing instruments.
Methoxypolyethylene glycol 350 is employed in the manufacturing of industrial coatings, paints, and varnishes for its film-forming properties.

Methoxypolyethylene glycol 350 is inert and does not interact with most drug molecules.
Methoxypolyethylene glycol 350 exhibits minimal toxicity and is generally considered safe for topical and oral use.
When used as a lubricant, Methoxypolyethylene glycol 350 reduces friction and wear in mechanical systems.

Its high thermal stability makes it suitable for applications in various temperature ranges.
Methoxypolyethylene glycol 350 forms stable emulsions with oils and other hydrophobic substances.

Methoxypolyethylene glycol 350 can be easily dispersed in aqueous solutions to form homogeneous mixtures.
Methoxypolyethylene glycol 350 is odorless and tasteless, making it ideal for pharmaceutical formulations.

Methoxypolyethylene glycol 350 has a long shelf life and maintains its properties over a wide range of storage conditions.
Methoxypolyethylene glycol 350 is often used as a carrier for active ingredients in transdermal drug delivery systems.

Methoxypolyethylene glycol 350 exhibits good biocompatibility and is well-tolerated by the skin.
Its low molecular weight allows for rapid absorption and distribution in biological tissues.

Methoxypolyethylene glycol 350 can be easily modified to tailor its properties for specific applications.
In cosmetics, Methoxypolyethylene glycol 350 enhances the stability and shelf life of emulsions and suspensions.

Methoxypolyethylene glycol 350 is non-ionic and does not interfere with the pH of formulations.
When incorporated into oral suspensions, it prevents settling and ensures uniform drug distribution.

Methoxypolyethylene glycol 350 is widely used in the formulation of eye drops and ophthalmic solutions.
Methoxypolyethylene glycol 350 undergoes minimal metabolism in the body, leading to low systemic exposure.



DESCRIPTION


Methoxypolyethylene glycol 350, also known as MPEG-350, is a chemical compound belonging to the class of polyethylene glycols (PEGs).
PEGs are polymers composed of repeating ethylene oxide units. MPEG-350 specifically has an average molecular weight around 350 Daltons.

Methoxypolyethylene glycol 350 is commonly used in various industries including pharmaceuticals, cosmetics, and as a lubricant in mechanical applications.
In pharmaceuticals, Methoxypolyethylene glycol 350 can be found in formulations such as ointments, creams, and oral dosage forms, where it acts as a solubilizing agent, emulsifier, or viscosity modifier.
In cosmetics, Methoxypolyethylene glycol 350 is used in products like creams, lotions, and shampoos for its moisturizing and emulsifying properties.

Methoxypolyethylene glycol 350 is a water-soluble polymer commonly used in pharmaceutical formulations.
Methoxypolyethylene glycol 350 exhibits excellent solubility in both polar and nonpolar solvents.

Methoxypolyethylene glycol 350 is characterized by its clear, colorless appearance and low viscosity.
Methoxypolyethylene glycol 350 serves as an effective solubilizing agent for poorly soluble drugs in pharmaceutical preparations.
Due to its amphiphilic nature, Methoxypolyethylene glycol 350 acts as a versatile emulsifier in cosmetic products.

When incorporated into creams and lotions, it imparts a smooth, non-greasy texture.
In oral dosage forms, Methoxypolyethylene glycol 350 enhances drug stability and bioavailability.
Methoxypolyethylene glycol 350 is compatible with a wide range of active pharmaceutical ingredients (APIs).



PROPERTIES


Physical Properties:

Appearance: Clear, colorless liquid
Odor: Odorless
Molecular Weight: Approximately 350 g/mol
Melting Point: Below room temperature (liquid at room temperature)
Boiling Point: Typically above 100°C (dependent on molecular weight and purity)
Density: Varies, typically around 1.0 g/cm³
Solubility: Soluble in water and many organic solvents
Viscosity: Low to moderate viscosity, dependent on concentration and temperature
Refractive Index: Typically around 1.45 (dependent on purity and temperature)
Flash Point: Not applicable (non-flammable)


Chemical Properties:

Chemical Formula: (C2H4O)n(CH4O)x
Chemical Structure: Linear polymer consisting of repeating ethylene oxide units with methoxy end-groups
Hydrophilicity: Highly hydrophilic due to the presence of ethylene oxide units
pH: Neutral (approximately 7)
Stability: Chemically stable under normal conditions
Reactivity: Non-reactive under typical conditions, inert towards most chemicals
Biodegradability: Generally considered biocompatible and biodegradable
Toxicity: Low toxicity, considered safe for many applications
Flammability: Non-flammable
Compatibility: Compatible with a wide range of substances, including pharmaceuticals, cosmetics, and polymers.



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air.
If breathing is difficult, administer oxygen if available and trained to do so.
Seek medical attention if symptoms persist or worsen.


Skin Contact:

Remove contaminated clothing and rinse affected skin thoroughly with water.
Wash skin with mild soap and water.
Seek medical attention if irritation or redness persists.


Eye Contact:

Flush eyes with lukewarm water for at least 15 minutes, lifting the eyelids occasionally.
Seek immediate medical attention, even if irritation is mild or absent.


Ingestion:

Rinse mouth thoroughly with water.
Do not induce vomiting unless instructed to do so by medical personnel.
Seek immediate medical attention.
If person is conscious, provide water or milk to dilute the substance if recommended by medical personnel.



HANDLING AND STORAGE

Handling:

Personal Protective Equipment (PPE):
Wear appropriate personal protective equipment, including safety glasses or goggles, gloves, and protective clothing, when handling Methoxypolyethylene glycol 350 to minimize skin and eye contact.

Ventilation:
Use adequate ventilation in areas where Methoxypolyethylene glycol 350 is handled to prevent the buildup of vapor or mist.

Handling Precautions:
Avoid breathing vapors or mist generated from Methoxypolyethylene glycol 350.
Prevent skin and eye contact by wearing appropriate protective clothing and equipment.
Do not eat, drink, or smoke while handling the substance.
Wash hands thoroughly with soap and water after handling Methoxypolyethylene glycol 350.

Spill and Leak Procedures:
In case of a spill, contain the spill immediately to prevent spreading.
Absorb spilled material with inert absorbent material (e.g., sand, vermiculite) and collect in a suitable container for disposal.
Clean contaminated surfaces thoroughly with water and detergent.

Fire and Explosion Hazards:
Methoxypolyethylene glycol 350 is non-flammable and not combustible under normal conditions.


Storage:

Storage Conditions:
Store Methoxypolyethylene glycol 350 in a cool, dry, well-ventilated area away from direct sunlight and heat sources.
Keep containers tightly closed when not in use to prevent contamination and evaporation.
Store away from incompatible materials, such as strong oxidizing agents and acids.

Temperature Control:
Maintain storage temperature within the specified range to prevent degradation or changes in properties.
Avoid exposure to extreme temperatures, as it may affect the stability and performance of Methoxypolyethylene glycol 350.

Container Compatibility:
Use containers made of suitable materials, such as high-density polyethylene (HDPE) or glass, that are compatible with Methoxypolyethylene glycol 350.
Ensure containers are labeled properly with appropriate hazard warnings and handling instructions.

Avoid Contamination:
Prevent contamination of Methoxypolyethylene glycol 350 by keeping storage areas clean and free from dust, dirt, and other foreign materials.
Do not store or use near food, beverages, or animal feed to avoid accidental ingestion or contamination.

Handling Precautions:
Follow all safety precautions and guidelines provided by the manufacturer and regulatory agencies for safe handling and storage of Methoxypolyethylene glycol 350.
Keep storage areas well-marked and secure to prevent unauthorized access or tampering.


METHOXYPOLYETHYLENE GLYCOL 500
Methoxypolyethylene glycol 500, also known as mPEG 500, is a type of polyethylene glycol (PEG) derivative. PEGs are water-soluble, non-toxic, and biocompatible polymers that are widely used in various pharmaceutical, medical, and industrial applications.
Methoxypolyethylene glycol 500s - polymers of ethylene oxide and methanol, represented by the generalized formula CH3O-(CH2-CH2-O)n-H, with ‘n’ indicating the average number of oxyethylene groups.
Methoxypolyethylene glycol 500 has specific properties that make it useful in various applications.

CAS Number: 9004-74-4
Molecular Formula: CH3(OCH2CH2)nOH
Molecular Weight: 450-550

Methoxypolyethylene glycol 500 is also utilized in various biotechnological and research applications, where its biocompatibility and hydrophilic nature make it suitable for applications like protein purification, as it can improve the solubility and stability of biomolecules.
The number "500" in the name refers to the approximate molecular weight of the PEG, which is around 500 Daltons.
Methoxy polyethylene glycols are available in average molecular weights ranging from 350 to 5000.

All MPEGs are designated by a number indicating the average molecular weight.
Methoxypolyethylene glycol 350 and 500 are clear viscous liquids at room temperature but MPEG 750 and 1000 require a temperature above 40°C.
Methoxypolyethylene glycol 2000, 3000 and 5000 are white waxy solids that are supplied in flake form.

Some grades may also be supplied in molten form. For special product demands, information on applications or other special requirements contact the local sales office.
Methoxypolyethylene glycol 500 is often used in the pharmaceutical industry as an excipient in drug formulations, particularly in the development of controlled-release drug delivery systems.
Methoxypolyethylene glycol 500 can modify the solubility, stability, and bioavailability of certain drugs.

Methoxypolyethylene glycol 500 (the process of attaching PEG chains to molecules) is used to extend the circulation time of drugs in the body and reduce their immunogenicity.
Methoxypolyethylene glycol 500 are addition polymers of ethylene oxide and methanol, represented by the generalised formula CH3O-(CH2-CH2-O)n-H, with Œn¹ indicating the average number of oxyethylene groups.
In chemical abstracts Methoxypolyethylene glycol 500s are described under the scientific name Poly(oxy-1,2-ethanediyl)-a-methyl-w-hydroxy in combination with the CAS register number 9004-74-4.

Other names are Methoxypolyethylene glycol 500 and methoxy polyethylene glycol.
Methoxypolyethylene glycol 500 are soluble in many polar solvents as aliphatic ketones, alcohols, glycol ethers, esters and aromatic hydrocarbons.
Methoxypolyethylene glycol 500s are readily miscible with water, the solid MPEGs are slightly less soluble in water with their solubility decreasing as molecular weight increases.

Methoxypolyethylene glycol 500 appears as a clear, colorless liquid.
Methoxypolyethylene glycol 500 is a polymer similar in structure and nomenclature to polyethylene glycols.
Methoxypolyethylene glycol 500 cross-linked polymeric materials (hydrogels) are suitable carriers for drug delivery and various other biomedical applications.

Methoxypolyethylene glycol 500 is a hydrophilic macromonomer used to introduce hydrophilic sites into polymers, to stabilize polymer emulsions, and in synthesis of comb polymers.
Methoxypolyethylene glycol 500 is less dense than water.
It is a Methoxypolyethylene glycol 500 with a reactive chain end consisting of methyl ether.

Methoxypolyethylene glycol 500 chain ends can be undertaken in basic conditions by reacting it with alkyl halides.
Methoxypolyethylene glycol 500 can undergo cross linking to form hydrogels; polymerization can be initiated by redox reaction or free radical initiator.
Methoxypolyethylene glycol 500 is a hydroxyether, ethanol substituted at position 2 by a methoxy group.

Methoxypolyethylene glycol 500 acts as a protic solvent and solvent.
Methoxypolyethylene glycol 500 has a flash point of 110°F.
The vapors of Methoxypolyethylene glycol 500 are heavier than air.

Methoxypolyethylene glycol 500, commonly known as PEG 350, is a type of polyethylene glycol (PEG) compound.
Polyethylene Glycols (PEGs) and Methoxypolyethylene glycol 500 are among the most versatile chemical ingredients available to formulators and manufacturers.
Since 1940, Methoxypolyethylene glycol 500 have set industry standards for innovation, performance, formulation flexibility and quality.

Formulators in a wide range of industries value the contributions Methoxypolyethylene glycol 500 make to their products, including enhanced solvency, lubricity, hygroscopicity, and other important functional properties.
Manufacturing chemists choose Methoxypolyethylene glycol 500 to improve production processes, in applications including mold and mandrel releases, lubricants, anti-static agents and other processing aids.

Methoxypolyethylene glycol 500 can also be used as chemical intermediates, resulting in products for foam control, thickeners, and resins.
Methoxypolyethylene glycol 500, from colourless and odourless viscous liquids to waxy solids.
Methoxypolyethylene glycol 500 as the molecular weight increases, its hygroscopic capacity decreases accordingly.

Methoxypolyethylene glycol 500 is soluble in water, ethanol and many other organic solvents.
Methoxypolyethylene glycol 500 has a low vapour pressure and is stable to heat, acids and bases.
Methoxypolyethylene glycol 500 does not interact with many chemicals.

Methoxypolyethylene glycol 500 has good hygroscopicity, lubricity and bonding properties.
Methoxypolyethylene glycol 500s can be chemically modified to create various derivatives with specific properties.
Methoxypolyethylene glycol 500 is used as lubricating agents in various medical devices and formulations.

These can reduce friction and improve the glide of medical instruments, catheters, and devices that come into contact with body tissues.
Methoxypolyethylene glycol 500 nanoparticles and micelles are employed in medical imaging techniques such as magnetic resonance imaging (MRI) and positron emission tomography (PET).
Methoxypolyethylene glycol 500 can act as adjuvants in vaccines, enhancing the body's immune response to antigens and improving the effectiveness of the vaccine.

Methoxypolyethylene glycol 500 is used to stabilize proteins during various stages of production, purification, and storage.
This helps prevent protein denaturation and aggregation, maintaining their biological activity.
Methoxypolyethylene glycol 500 is commonly used in laboratory research for tasks like protein precipitation, DNA extraction, and the separation of molecules based on their size through techniques like polyacrylamide gel electrophoresis (PAGE).

Methoxypolyethylene glycol 500 are commonly found in personal care and cosmetic products due to their ability to improve the texture, spreadability, and moisturizing properties of creams, lotions, shampoos, and other products.
For example, the addition of fatty acids to Methoxypolyethylene glycol 500 molecules can lead to compounds known as PEGylated lipids, which are used in drug delivery systems and as components of lipid-based formulations.

Methoxypolyethylene glycol 500s are widely used in drug delivery systems to improve the delivery of drugs to specific target tissues and to enhance their stability in the bloodstream.
Methoxypolyethylene glycol 500 of drugs can also reduce their immunogenicity, extending their circulation time and potentially improving their therapeutic efficacy.
Methoxypolyethylene glycol 500 hydrogels are crosslinked networks of PEG molecules that can hold a large amount of water.

Methoxypolyethylene glycol 500s are synthetic polymers made by polymerizing ethylene oxide, and they are widely used in various industries due to their versatile properties.
Methoxypolyethylene glycol 500 specifically refers to a PEG compound where the average molecular weight is around 350 g/mol.
The molecular weight of Methoxypolyethylene glycol 500 can vary significantly, and different molecular weights result in different properties and uses.

Methoxypolyethylene glycol 500 shows improved solubility, slipperiness, hygroscopicity and slightly more hydrophobic solvent properties.
They are suitable for use in soaps and detergents, adhesives, chemical intermediates, inks and paint carriers, lubricants and plasticizers.
Methoxypolyethylene glycol 500 is part of a family of compounds with a polyethylene glycol backbone.

The "methoxy" in the name refers to the presence of methoxy (-OCH3) groups attached to the PEG structure.
These methoxy groups can affect the chemical and biological properties of the molecule.
One of the primary reasons for using PEG derivatives like Methoxypolyethylene glycol 500 is their high solubility in water.

This characteristic makes them useful in formulating drugs, especially for intravenous administration, as they can improve the solubility of poorly water-soluble compounds.
Methoxypolyethylene glycol 500, are known for their biocompatibility.
They are generally well-tolerated by the human body and have low immunogenicity, making them suitable for use in pharmaceuticals and medical applications.

Methoxypolyethylene glycol 500 is often used in drug delivery systems. When PEG is attached to drug molecules or nanoparticles, it can extend their circulation time in the bloodstream, reduce clearance by the immune system, and enhance drug delivery to target tissues.
This is particularly valuable in the development of long-acting or sustained-release medications.

In biochemistry and biotechnology, Methoxypolyethylene glycol 500 can be used to stabilize proteins and enzymes.
Methoxypolyethylene glycol 500 can improve their solubility, prevent aggregation, and enhance their longevity, which is important in various research and industrial processes.
Methoxypolyethylene glycol 500 is often used as a building block for creating more complex polymers or conjugates.

By modifying the end groups of Methoxypolyethylene glycol 500 chains, it's possible to attach other functional groups or molecules, enabling a wide range of customizations for specific applications.
Methoxypolyethylene glycol 500, there are PEG derivatives with a wide range of molecular weights, from smaller PEGs to much larger ones.
The choice of PEG depends on the specific application and the desired properties.

Methoxypolyethylene glycol 500 has the form of white flakes.
Methoxypolyethylene glycol 500 has an average molecular mass of 350.
Methoxypolyethylene glycol 500 is used in various applications such as micelles as well as drug delivery.

Methoxypolyethylene glycol 500 is used in modifications of therapeutic proteins to improve their pharmacokinetics.
Methoxypolyethylene glycol 500, a new grade.

Appearance 23C: Solid
Melting point: 30 °C
Boiling point: >200°C/760mmHg
Density: 1.094 g/mL at 25 °C
vapor density: >1 (vs air)
vapor pressure: 0.05 mm Hg ( 20 °C)
refractive index: n20/D 1.459
Flash point: 268 °C
storage temp.: -20°C
solubility H2O: 50 mg/mL at 25 °C, clear, colorless
form: semisolid
Specific Gravity: 1.094
color: White to pale yellow
PH: 5.5-7.0 (25℃, 50mg/mL in H2O)
Water Solubility: Slightly miscible with water.
λmax λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03
Stability: Stable. Incompatible with strong oxidizing agents, strong acids, strong bases.
LogP: -0.800 (est)

Methoxypolyethylene glycol 500 is used to modify drugs or therapeutic molecules, it can increase their circulation time in the body.
This property is particularly valuable in creating sustained or prolonged drug actions.
Methoxypolyethylene glycol 500 can reduce the frequency of drug administration, making it more convenient for patients.

Methoxypolyethylene glycol 500, is employed to reduce the immunogenicity of certain therapeutic proteins and peptides.
When these molecules are modified with PEG, they are less likely to trigger an immune response, which is crucial for enhancing the safety and efficacy of biopharmaceuticals.
Methoxypolyethylene glycol 500 is used in the development of various drug delivery systems, such as liposomes, micelles, and nanoparticles.

These systems can encapsulate drugs and enhance their delivery to specific target sites, such as tumors in the case of cancer therapy.
Methoxypolyethylene glycol 500 can serve as a component of the outer layer of these drug carriers to improve their stability and circulation time.
In addition to drug delivery systems, Methoxypolyethylene glycol 500 is used to modify the surface properties of various materials, including nanoparticles and biomaterials.

The hydrophilic and non-fouling nature of Methoxypolyethylene glycol 500 can reduce interactions with biological molecules and cells, making it useful in applications like coatings for medical devices and nanoparticles used in diagnostics and drug delivery.
Methoxypolyethylene glycol 500 can enhance the chemical and physical stability of molecules, particularly proteins and peptides.
This is valuable for extending the shelf life of biopharmaceuticals and ensuring their effectiveness during storage and transport.

Methoxypolyethylene glycol 500 and similar PEG derivatives are sometimes used in toxicology and pharmacokinetic studies to assess the safety and distribution of potential drugs.
This can provide valuable data for drug development.
Methoxypolyethylene glycol 500 is used in conjugation chemistry to attach PEG chains to molecules of interest.

This can involve covalent bonding or other chemical interactions to create PEG-conjugated compounds with unique properties.
Methoxypolyethylene glycol 500 extends beyond the pharmaceutical and medical fields.
Methoxypolyethylene glycol 500 is also utilized in various other industries, including cosmetics, food, and industrial processes where water-soluble, non-toxic, and biocompatible materials are needed.

Methoxypolyethylene glycol 500 and other PEG compounds are utilized in the pharmaceutical industry to enhance the solubility of poorly water-soluble drugs, thereby improving their bioavailability.
Methoxypolyethylene glycol 500 can also be used to modify the release rate of drugs from dosage forms.
Methoxypolyethylene glycol 500 is a process where PEG molecules are attached to drugs or therapeutic proteins.

This modification can improve the pharmacokinetics and stability of the molecules in the body, resulting in prolonged circulation times and reduced immunogenicity.
The properties of PEGs like Methoxypolyethylene glycol 500 can be tuned by altering their molecular weights.
Methoxypolyethylene glycol 500s tend to be more viscous and can form thicker gels, while lower molecular weight PEGs are more liquid and less viscous.

Methoxypolyethylene glycol 500 can act as plasticizers in plastics and polymers, improving flexibility and reducing brittleness.
Methoxypolyethylene glycol 500 is sometimes used in chromatography and electrophoresis techniques for separation and analysis of biomolecules.
Methoxypolyethylene glycol 500-based compounds are used in personal lubricants due to their water-retaining properties and lubricating effects.

Methoxypolyethylene glycol 500s themselves are generally considered biocompatible and safe, there have been concerns about their potential impact on aquatic ecosystems due to their persistence and potential to bioaccumulate.
Methoxypolyethylene glycol 500s are generally considered safe for use in various applications, including pharmaceuticals, cosmetics, and food, when used within specified concentrations.
However, there can be concerns about potential skin irritation and sensitization, especially if used on damaged or compromised skin.

Methoxypolyethylene glycol 500 is a PEG-6 methyl ether based plasticizer.
Methoxypolyethylene glycol 500 maintains wet adhesion strength and has lubricity and moisturizing properties.
Methoxypolyethylene glycol 500 is used in pressure sensitive and thermoplastic adhesives.

Methoxypolyethylene glycol 500 is soluble in many polar solvents such as aliphatic ketones, alcohols, glycol ethers.
Methoxypolyethylene glycol 500 is easily miscible with water.
Methoxypolyethylene glycol 500 is slightly less soluble in water and its solubility is reduced molecularly.

Methoxypolyethylene glycol 500 is a long chain methacrylate monoester based on an ethylene oxide backbone.
Methoxypolyethylene glycol 500 is water soluble and contains about 8 ethylene oxide (EO) units in its structure.

Methoxypolyethylene glycol 500 is a Polyethylene glycol (PEG) macromer with a reactive chain end consisting of.
Methoxypolyethylene glycol 500 is less dense than water.
Methoxypolyethylene glycol 500 by Dow is PEG-6 methyl ether-based plasticizer.

Methoxypolyethylene glycol 500 maintains wet-tack strength and possesses lubricity and humectant properties.
Methoxypolyethylene glycol 500 has improved solubility, slipperiness, hygroscopicity and light weight.

Methoxypolyethylene glycol 500 is used in lubricants and plasticizers.
Methoxypolyethylene glycol 500 has the form of a viscous liquid to white flakes.

Methoxypolyethylene glycol 500 chain ends can be assumed by reacting with alkyl under basic conditions.
Methoxypolyethylene glycol 500 is used in various applications such as micelles as well as drug delivery.
Methoxypolyethylene glycol 500, a new grade heat sensitive micelle cyclotriphosphazenes.

Methoxypolyethylene glycol 500 is a hydroxyether, ethanol substituted at position 2 by a methoxy group.
Methoxypolyethylene glycol 500 acts as a protic solvent and solvent.
Methoxypolyethylene glycol 500 appears as a clear, colorless liquid.

Methoxypolyethylene glycol 500 has an average molecular mass of 350.
Methoxypolyethylene glycol 500 is used for drug delivery.
Methoxypolyethylene glycol 500 is a macromer with a reactive chain end consisting of methyl ether.

Methoxypolyethylene glycol 500 was also used in a study to investigate the synthesis of a new amphiphilic compound.
Methoxypolyethylene glycol 500 were synthesized through bromoacetylation of potato starch followed by substitution of methoxy poly (ethylene glycol) (MPEG)with various MWs (MPEG-500, MPEG-2000, and MPEG-5000). Grafting was performed at 50°C.
Methoxypolyethylene glycol 500 is soluble in many polar solvents such as aliphatic ketones, alcohols, glycol ethers.

Methoxypolyethylene glycol 500 is easily miscible with water.
Methoxypolyethylene glycol 500 was also used in a study to investigate the synthesis of a new amphiphilic compound.

Methoxypolyethylene glycol 500 with stepwise nucleophilic substitution.
Methoxypolyethylene glycol 500 is the main material for producing polycarboxylate high water reducing agent.

Uses:
Methoxypolyethylene glycol 500 are used in pharmacology and cosmetics production; detergent & household goods production (as soap bars glue, soluble agent in detergent pastes, fixing agent for odors in soaps and detergents, as additive in general cleaners, polishers, air fresheners, automatic dishwashing detergents); in production of textile supporting substances (as component of dispergators and protective solutions); in metal works industry (as agents for cleaning and polishing pastes, lubricating & cooling liquids).
Methoxypolyethylene glycol 500 is used in various applications such as micelles for drug delivery as well as in modifications of therapeutic proteins to improve their pharmacokinetics.

Methoxypolyethylene glycol 500 help moisturize the skin and improve the texture of products like lotions, creams, and shampoos.
Methoxypolyethylene glycol 500s find applications in industrial processes such as in the manufacturing of adhesives, lubricants, and as antifoaming agents.
Methoxypolyethylene glycol 500 is also used in the food industry, particularly in food packaging and processing.

They can act as stabilizers, thickeners, and moisture-retaining agents.
Methoxypolyethylene glycol 500 is used to improve drug solubility, enhance drug stability, and control drug release in various dosage forms.
Methoxypolyethylene glycol 500 hydrogels can be used for wound dressings to maintain a moist environment and promote healing.

Methoxypolyethylene glycol 500 is used to modify drugs, peptides, and proteins to enhance their solubility, stability, and bioavailability.
Methoxypolyethylene glycol 500 can also prolong the circulation time of therapeutic molecules in the body, making it valuable in the development of long-acting or sustained-release medications.
Methoxypolyethylene glycol 500 reduces the immunogenicity of biopharmaceuticals, making them safer for use in patients.

Methoxypolyethylene glycol 500 lubricants can be used during surgical procedures and are especially useful in laparoscopic surgery.
Methoxypolyethylene glycol 500 derivatives can be found in topical medications and personal care products.
Methoxypolyethylene glycol 500 is used to stabilize proteins and enzymes, particularly in research and diagnostic applications.

Methoxypolyethylene glycol 500 molecules can be employed in various assays and tests to improve sensitivity and accuracy.
Methoxypolyethylene glycol 500 is used in the creation of hydrogels for cell culture and tissue engineering applications.
Methoxypolyethylene glycol 500 is used in the development of drug delivery systems, such as liposomes and micelles, to improve drug solubility and enhance targeted drug delivery.

Methoxypolyethylene glycol 500 derivatives can be found in a wide range of cosmetic and personal care products, including skin creams, shampoos, and lotions, where they act as emollients, emulsifiers, and stabilizers.
Methoxypolyethylene glycol 500G may be used as an emulsifying agent, stabilizer, or a texture-modifying additive in various products, such as ice cream, salad dressings, and bakery goods.
Methoxypolyethylene glycol 500 is used in various industrial applications, such as metalworking, where it serves as a lubricant and coolant.

Methoxypolyethylene glycol 500 is also used in textiles and as a component of antifreeze.
Methoxypolyethylene glycol 500 can be used in diagnostic assays, particularly in immunoassays, to improve the performance and stability of reagents.
Methoxypolyethylene glycol 500 is used in a wide range of molecular biology and chemistry techniques, such as DNA extraction, PCR, and protein purification.

Methoxypolyethylene glycol 500 derivatives can be used in toxicological studies to assess the safety and distribution of chemicals and drugs.
Methoxypolyethylene glycol 500 are used to deliver genetic material for gene therapy applications.
Methoxypolyethylene glycol 500 nanoparticles enhance imaging contrast and targeted drug delivery in medical imaging techniques.

Methoxypolyethylene glycol 500 hydrogels are employed as scaffolds for tissue regeneration and repair.
Methoxypolyethylene glycol 500s reduce friction and improve lubrication in medical devices and catheters.
Methoxypolyethylene glycol 500s are used in lotions, creams, and moisturizers for their humectant properties.

Methoxypolyethylene glycol 500 extends the circulation time of therapeutic proteins and drugs, reducing immunogenicity and improving efficacy.
Methoxypolyethylene glycol 500 was used in a study to evaluate the synthesis of a new class of heat sensitive micelles.
Methoxypolyethylene glycol 500 was also used in a study to investigate the synthesis of a new amphiphilic compound.

Methoxypolyethylene glycol 500 has been used in a study to assess the synthesis of a new class of thermosensitive micellar cyclotriphosphazenes.
Methoxypolyethylene glycol 500 has also been used in a study to investigate synthesis of a new amphiphilic poly(organophosphazene) by stepwise nucleophilic substitution.
Methoxypolyethylene glycol 500 commonly used in pharmaceuticals as excipients (inactive ingredients) in various formulations.

Methoxypolyethylene glycol 500s enhance packaging materials' moisture retention properties.
Methoxypolyethylene glycol 500s improve the smoothness and texture of ice cream by reducing ice crystal formation.
Methoxypolyethylene glycol 500s improve dough handling properties and texture in baked goods.

Methoxypolyethylene glycol 500s serve as lubricants in various industries, including manufacturing and machinery.
Methoxypolyethylene glycol 500 improve the adhesive properties of formulations in the adhesive industry.
Methoxypolyethylene glycol 500 enhance textile processing by improving the flexibility and manageability of fabrics.

They can act as solubilizers, stabilizers, and viscosity modifiers in oral solutions, ointments, creams, and other dosage forms.
Methoxypolyethylene glycol 500 can serve as lubricants and coolants in metalworking processes such as cutting, drilling, and grinding.
Methoxypolyethylene glycol 500 have been explored as absorbents for carbon capture from industrial processes, helping to mitigate greenhouse gas emissions.

Methoxypolyethylene glycol 500 is used to attach molecules to biological entities, enabling various research and medical applications.
Methoxypolyethylene glycol 500 and other PEG derivatives are used in organic chemistry as a protecting group for functional groups during chemical reactions.
They can be attached to specific molecules to shield certain chemical moieties, allowing for selective reactions, and then removed under controlled conditions.

Methoxypolyethylene glycol 500 can be applied to diagnostic agents and contrast agents used in imaging techniques like MRI (Magnetic Resonance Imaging) and CT (Computed Tomography) scans to improve their stability and specificity.
Methoxypolyethylene glycol 500 is commonly used in nanotechnology for the modification of nanoparticles.
Methoxypolyethylene glycol 500 can reduce their opsonization and improve their circulation time in the bloodstream.

This is valuable in the development of targeted drug delivery systems and imaging agents.
Methoxypolyethylene glycol 500 derivatives like mPEG 500 are used to modify the surfaces of materials to make them more resistant to fouling and enhance their biocompatibility.
This is essential in the development of medical implants, biosensors, and various biomedical devices.

Methoxypolyethylene glycol 500 is used in some agricultural applications to improve the effectiveness of certain pesticides and herbicides by increasing their solubility and dispersion.
Methoxypolyethylene glycol 500 is used in drilling fluids to help reduce friction and control the viscosity of drilling mud, which is important in oil and gas exploration and drilling processes.

Methoxypolyethylene glycol 500 materials can be found in adhesives and sealants, where they contribute to the product's durability and workability.
Methoxypolyethylene glycol 500 can be used in the electronics industry for various applications, such as encapsulating electronic components, controlling humidity in electronic devices, and serving as a dielectric material.

Methoxypolyethylene glycol 500 is employed in the paper and packaging industry for its anti-static properties and ability to enhance the quality of paper coatings.
Methoxypolyethylene glycol 500is used as a softening agent and finishing agent for leather and textiles, improving their feel and appearance.
Methoxypolyethylene glycol 500 derivatives can be used in wastewater treatment processes to improve the flocculation and sedimentation of suspended particles.

Methoxypolyethylene glycol 500 is a key component in the development of nanoparticles for targeted drug delivery and diagnostics.
Methoxypolyethylene glycol 500 hydrogels can respond to environmental stimuli, making them useful in smart materials and drug delivery systems.
Methoxypolyethylene glycol 500-based microfluidic devices are used for precise manipulation of small fluid volumes in lab-on-a-chip applications.

Methoxypolyethylene glycol 500-based materials are explored in 3D printing for their biocompatibility and ability to create complex structures.
Methoxypolyethylene glycol 500 is used in laboratory settings as reaction solvents and reagents in various chemical reactions.
Methoxypolyethylene glycol 500 is used in cosmetics and personal care products as emollients, humectants, and thickeners.

Safety:
While rare, some individuals may develop allergic reactions to PEG or Methoxypolyethylene glycol 500-containing products.
These reactions can range from mild skin irritation to more severe symptoms such as hives, itching, and difficulty breathing.
Methoxypolyethylene glycol 500's essential to be aware of potential allergies and conduct skin patch tests when using PEG-containing personal care or medical products.

Methoxypolyethylene glycol 500 can lead to gastrointestinal upset, including diarrhea, abdominal cramps, and nausea.
This is typically associated with the consumption of laxatives or other oral preparations containing PEG.
Depending on the manufacturing process and quality control, Methoxypolyethylene glycol 500 products may contain trace impurities or contaminants.

Methoxypolyethylene glycol 500 vapor or aerosol exposure in industrial settings can potentially irritate the respiratory system.
Adequate ventilation and personal protective equipment may be necessary to mitigate this risk. Methoxypolyethylene glycol 500's important to follow recommended guidelines and avoid excessive ingestion.

Methoxypolyethylene glycol 500-containing products can cause eye irritation if they come into contact with the eyes.
Avoid direct eye contact and rinse thoroughly with water if contact occurs.
Methoxypolyethylene glycol 500s can be manufactured using various processes that might introduce impurities or contaminants.

While reputable suppliers take measures to ensure the purity of their products, impurities could potentially lead to adverse reactions.
High concentrations of Methoxypolyethylene glycol 500s can have laxative effects when ingested orally.

Synonyms:
Dodecaethylene Glycol Monomethyl Ether
5702-16-9
mPEG12-OH
m-PEG12-alcohol
m-PEG12-OH
2050595-03-2
2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaheptatriacontan-37-ol
2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
MFCD06797088
Methyl-PEG12-alcohol
SCHEMBL540078
PLQZJIIDLZRWBG-UHFFFAOYSA-N
Dodecaethyleneglycol monomethyl ether
AKOS022174862
GS-6121
BP-22581
SY111226
Methoxypolyethylene glycols-average Mn 500
HY-141220
CS-0114732
D2904
Dodecaethylene glycol monomethyl ether, 95%
Methoxypolyethylene glycols-average PEG(36)
H10538
Methoxypolyethylene glycols-average M.W. 20000
A869784
J-520424
Methoxypolyethylene glycols-average-average Mn 21500
Methoxypolyethylene glycols-average-average Mn 30000
METHOXYPOLYETHYLENE GLYCOL 750
Methoxypolyethylene glycol 750 is intended mainly for the construction industry.
The average molecular weight of Methoxypolyethylene glycol 750 is 750 g/mol.


CAS Number: 9004-74-4
MDL Number: MFCD00084416
INCI Name: Methoxy PEG-16
Chem/IUPAC Name: Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-methoxy- (16 mol EO average molar ratio)
Molecular Formula: CH3O(CH2CH2O)nH



SYNONYMS:
mPEG-alkyne, poly(ethylene glycol)methyl ether acetylene, mPEG-acetylene, Methoxy polyethylene glycol, MPEG, METHOXY PEG-17, (Methoxy polyethylene glycol), CAS 9004-74-4, Methoxy Polyethylene Glycol, methoxy polyethylene glycol methacrylate 750, Methoxypolyethylene glycols 750, Poly(ethylene glycol) methyl ether, Methoxy poly(ethylene glycol), Poly(ethylene glycol) methyl ether, mono-Methyl polyethylene glycol 350, Methoxypolyethylene glycol, Methoxypolyethylene glycol 350, Methoxypolyethylene glycol, Poly(ethylene glycol) methyl ether, mono-Methyl polyethylene glycol 350, mPEG , Methoxy poly(ethylene glycol) , Methoxypolyethylene glycols , PEG MME , Poly(ethylene glycol) methyl ether, methyl cellosolve, ethanol, 2-methoxy, ethylene glycol monomethyl ether, methyl oxitol, 2-methoxy-1-ethanol, methoxyethanol, 3-oxa-1-butanol, egme, monomethyl glycol, dowanol em, Poly(oxy-1,2-ethanediyl),α-methyl-ω-hydroxy-, Glycols,polyethylene,monomethyl ether, Polyethylene glycol monomethyl ether, Carbowax 350, Polyethylene glycol methyl ether, Ethylene oxide-methanol adduct, α-Methyl-ω-hydroxypoly(oxy-1,2-ethanediyl), Methyl polyglycol, Carbowax 750, Methoxypoly(ethylene glycol), Carbowax 550, Carbowax 2000, Carbowax 5000, Monomethoxypolyethylene glycol, MPEG, MPEG 5000, Monomethoxypolyoxyethylene, Nissan Uniox M 2000, Hymol PM, MPG 025, MPG 081, Nissan Uniox M 400, O-Methoxypolyethylene glycol, Breox MPEG 550, GN 8384, CP 2000 (polyoxyalkylene), CP 2000, Monomethoxy poly(ethylene oxide), Nissan Uniox M 550, Poly(ethylene oxide) monomethyl ether, Toho Me-PEG 400, Toho Me-PEG 1000, Uniox M 400, Nissan Uniol 1000, Nissan Uniol 550, MPEG 500, Nissan Uniox M 1000, Uniox M 1000, Uniox M 2000, Carbowax 750ME, MPG 130, Uniox M 550, Polyglycol M 750, Sanfine MM 2000, MPEG 350, MPEG 2000, MPEG 10000, Nissan Uniox M 600, Carbowax MPEG 5000, Pluriol A 500E, Pluriol A 350E, Pluriol A 275E, Nissan Uniox M 4000, MPEG 950, Sunbright MEH 20T, MPG, Carbowax MPEG 450, Pluriol A 2000E, MPG 140, Pluriol A 2000, Methoxy PEG 400, Me-PEG 400, Conion MP 220, Polyoxyethylene monomethyl ether, Polyglycol M 5000S, Polyglycol M 2000S, M 550, 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-Heptadecaoxadopentacontan-52-ol, Pluriol 350E, M 750, MPEG 750, Pluriol 500, Polyglycol M 500, Uniox M 4000, Sunbright MEH 50H, Pluriol A 750I, Marlipal 1/12, 5702-16-9, 12623-96-0, 41396-14-9, 54386-07-1, 57244-93-6, 64543-87-9, 69592-91-2, 72664-19-8, 77102-87-5, 86002-19-9, 91826-72-1, 95507-78-1, 95507-80-5, 102868-77-9, 104841-59-0, 114740-40-8, 126966-17-4, 134919-42-9, 138753-86-3, 142172-77-8, 146162-92-7, 154701-70-9, 154885-26-4, 158360-78-2, 162582-19-6, 163294-10-8, 163733-28-6, 165338-17-0, 166441-82-3, 178613-33-7, 185250-24-2, 187523-66-6, 189209-93-6, 193008-24-1, 195970-98-0, 207799-14-2, 212969-32-9, 216693-45-7, 226212-72-2, 237739-71-8, 241466-57-9, 396134-26-2, MARLIPAL 1/7, METHOXY PEG-7, METHOXY PEG-7 [INCI], METHOXYPOLYETHYLENE GLYCOL 350, METHOXYPOLYOXYETHYLENE GLYCOL 350, MPEG 350, MPEG-7, PEG-7 METHYL ETHER, PEG-7 METHYL ETHER [II], PEG-7 METHYL ETHER [INCI], POLYETHYLENE GLYCOL (7) METHYL ETHER, POLYETHYLENE GLYCOL 350 METHYL ETHER, POLYXOYETHYLENE (7) METHYL ETHER, 9004-74-4, MARLIPAL 1/7, METHOXY PEG-7, METHOXY PEG-7 [INCI], METHOXYPOLYETHYLENE GLYCOL 350, METHOXYPOLYOXYETHYLENE GLYCOL 350, MPEG 350, MPEG-7, PEG-7 METHYL ETHER, PEG-7 METHYL ETHER [II], PEG-7 METHYL ETHER [INCI], POLYETHYLENE GLYCOL (7) METHYL ETHER, POLYETHYLENE GLYCOL 350 METHYL ETHER, POLYXOYETHYLENE (7) METHYL ETHER,



Methoxypolyethylene glycol 750 is methoxy PEG-16-based plasticizer.
Methoxypolyethylene glycol 750 possesses lubricity and humectant properties.
Methoxypolyethylene glycol 750 maintains wet-tack strength.


Methoxypolyethylene glycol 750 is a high molecular weight product that belongs to methoxy polyoxyethylene glycols.
Methoxypolyethylene glycol 750 is intended mainly for the construction industry.
The average molecular weight of Methoxypolyethylene glycol 750 is 750 g/mol.


Methoxypolyethylene glycol 750 is a white compact paste or solid.
Methoxypolyethylene glycol 750 is a polymer with high solubility in water and a slight odour.
The active substance content in Methoxypolyethylene glycol 750 is about 100%.


Methoxypolyethylene glycol 750 is soluble in water, ethanol and organic solvent.
Methoxypolyethylene glycol 750 has good water solubility, wettability, lubricity, physiological inertia, no stimulation to human body.


Methoxypolyethylene glycol 750 also reacts with acrylic acid to make MPEG acrylic acid ester, which is the main raw material for the preparation of polycarboxylate superplasticizer.
Methoxypolyethylene glycol 750 is a high molecular weight methoxy polyethylene glycol with excellent solubility in water.


Methoxypolyethylene glycol 750 is a polymer similar in structure and nomenclature to polyethylene glycols.
Methoxypolyethylene glycol 750 is PEG-6 methyl ether-based plasticizer.
Methoxypolyethylene glycol 750 maintains wet-tack strength and possesses lubricity and humectant properties.


Methoxypolyethylene glycol 750 is used in pressure-sensitive and thermoplastic adhesives.
Methoxypolyethylene glycol 750 is a polymer similar in structure and nomenclature to polyethylene glycols.
Methoxypolyethylene glycol 750 is a polymer similar in structure and nomenclature to polyethylene glycols.


Methoxypolyethylene glycol 750 is a hydrophilic macromonomer used to introduce hydrophilic sites into polymers and stabilize polymer emulsions.
Methoxypolyethylene glycol 750, with an average molecular weight of 750, is widely used in various industries.
Methoxypolyethylene glycol 750is a reliable raw material that can be utilized in the production of drugs, chemicals, and many other applications.


Also known as Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, and mPEG, Methoxypolyethylene glycol 750 has a range of potential uses.
Methoxypolyethylene glycol 750, commonly referred to as PEG 2000 Monomethylether, is a polyether compound that is used in a wide variety of fields including pharmaceutical manufacturing as an excipient and active ingredient.


Methoxypolyethylene glycol 750 is a hydrophilic macromonomer used to introduce hydrophilic sites into polymers and stabilize polymer emulsions.
It is a Methoxypolyethylene glycol 750 with a reactive chain end consisting of methyl ether.
Etherification of the Methoxypolyethylene glycol 750 chain ends can be undertaken in basic conditions by reacting it with alkyl halides.


Methoxypolyethylene glycol 750 can undergo cross linking to form hydrogels; polymerization can be initiated by redox reaction or free radical initiator.
Methoxypolyethylene glycol 750, known as Methoxy poly(ethylene glycol), is a powerful asset in research and industrial settings due to its excellent solubility and stability profile, and a wide range of applications.


Methoxypolyethylene glycol 750 is a high quality research product used as highly pure Poly(ethylene glycol) methyl ether (mPEG) with an average MW of 5000.
Methoxypolyethylene glycol 750, also referred to as Methoxy poly(ethylene glycol) or Polyethylene glycol monomethyl ether, is an exceptional and versatile compound designed to meet the diverse requirements of both research and industrial settings.


Methoxypolyethylene glycol 750, with its unique chemical formula and distinguished properties, pushes the boundaries of versatility, proving to be an indispensable tool for numerous professional applications.
Methoxypolyethylene glycol 750 offers ample flexibility with availability in bulk and pre-packs.


Methoxypolyethylene glycol 750, known as Methoxy poly(ethylene glycol), is a powerful asset in research and industrial settings due to its excellent solubility and stability profile, and a wide range of applications.
Methoxypolyethylene glycol 750 offers ample flexibility with availability in bulk and pre-packs.



USES and APPLICATIONS of METHOXYPOLYETHYLENE GLYCOL 750:
Methoxypolyethylene glycol 750 is mainly used in the construction industry for the production of superplasticizers in concrete admixtures and as a dispersant for pigments in paint and varnish production.
Methoxypolyethylene glycol 750 is used in many applications from industrial manufacturing to.


Its water solubility, wettability, and physiological characteristics make Methoxypolyethylene glycol 750 very attractive for the cosmetic industry.
Methoxypolyethylene glycol 750 is also used in food products and as a processing aid in many industrial applications.
Common uses of Methoxypolyethylene glycol 750 are as a surfactant, dispersing agent, solvent, excipient, and ointment.


Its functionality depends on Methoxypolyethylene glycol 750's molecular weight.
Methoxypolyethylene glycol 750 with a low molecular weight
average (less than 2000) is used as a wetting agent and viscosity modifier.


Higher molecular weight Methoxypolyethylene glycol 750 is used to produce MPEG acrylic esters, which are used as the efficient
reducing agent in the materials of constructions needed for high-strength structures.
The viscosity, hygroscopicity and structure of Methoxypolyethylene glycol 750 can be changed by selecting products with different molecular weight.


Methoxypolyethylene glycol 750 with relatively low molecular weight (molecular weight less than 2000) are suitable for wetting agents and consistency regulators for cream, lotion, toothpaste, and cream.
Methoxypolyethylene glycol 750 with relatively high molecular weight are suitable for lipstick, deodorant stick, soap, pick up soap, foundation and cosmetics.


In cleaning agent, Methoxypolyethylene glycol 750 is also used as suspending agent and thickener.
In the pharmaceutical industry, Methoxypolyethylene glycol 750 is used as the matrix of ointment, emulsion, ointment, lotion and suppository.
Low steam pressure, stable for heat, Methoxypolyethylene glycol 750 is used as thickener and lubricant in textile printing and dyeing industry and daily chemical industry.


Methoxypolyethylene glycol 750 is widely used in cosmetics and pharmaceutical industry.
Methoxypolyethylene glycol 750 can be used in the commercial concrete with high performance and high strength (above C60) which is mixed on site and transported remotely.


Methoxypolyethylene glycol 750 is mainly used for the production of polycarboxylate ether (PCE) superplasticizers for concrete.
Methoxypolyethylene glycol 750 is used in esterification reactions, e.g. with methacrylic acid which is further subjected to a polymerization process.
The resulting products are the main components of concrete admixtures that reduce the amount of batch water in cement concrete.


Comb polymers, resulting from emulsion polymerization using Methoxypolyethylene glycol 750, are used in paint and varnish production.
They are dispersants for organic and inorganic pigments.
Methoxypolyethylene glycol 750 is used the intermediate is used in the synthesis of superplasticizers (concrete admixtures),
the intermediate is used in the synthesis of pigment dispersants.


Methoxypolyethylene glycol 750 is used in pressure sensitive and thermoplastic adhesives.
Methoxypolyethylene glycol 750 that provides enhanced solvency, lubricity, hygroscopicity and with slightly more hydrophobic solvent properties.
Methoxypolyethylene glycol 750 is used for use in adhesives, chemical intermediates, and lubricants.


Methoxypolyethylene glycol 750 is used in a study to investigate synthesis of a new amphiphilic poly(organophosphazene) by stepwise nucleophilic substitution.
Methoxypolyethylene glycol 750 is widely used in biochemical research where its properties as a hydrophilic polymer are beneficial for modifying protein solubility and stability.


Methoxypolyethylene glycol 750 plays a significant role in the field of proteomics, assisting researchers in solubilizing proteins for structural analysis and functional studies.
In addition, Methoxypolyethylene glycol 750 is employed in nanoparticle research, where it is used to improve the dispersion and stability of nanoparticles in various solvents, facilitating studies on their potential applications.


Methoxypolyethylene glycol 750 is also pivotal in surface science, where it is applied to modify surfaces to resist protein and cell adhesion, crucial for investigating biomaterial interactions.
Moreover, Methoxypolyethylene glycol 750 is utilized in the synthesis of chemical delivery systems, where it enhances the bioavailability and controlled release of loaded agents, aiding in the exploration of new delivery methodologies.


Methoxypolyethylene glycol 750 is used as enteric release coatings.
Methoxypolyethylene glycol 750 is also used for a series of polycarboxylate water reducing agent.
Methoxypolyethylene glycol 750 acts as a solvent for brake fluids.


Further, Methoxypolyethylene glycol 750 is used in the building materials industry and raw material for cement water reducing agent and strengthening agent.
In addition to this, Methoxypolyethylene glycol 750 is used in surfactants, polyester and polyurethane based paints.
Methoxypolyethylene glycol 750 is used in a study to investigate synthesis of a new amphiphilic poly(organophosphazene) by stepwise nucleophilic substitution.


Methoxypolyethylene glycol 750 is used in a study to assess the synthesis of a new class of thermosensitive micellar cyclotriphosphazenes.
Methoxypolyethylene glycol 750 is used in a study to investigate synthesis of a new amphiphilic poly(organophosphazene) by stepwise nucleophilic substitution.


Methoxypolyethylene glycol 750 is intended for laboratory use only, and it is not meant for human consumption.
Methoxypolyethylene glycol 750 is a versatile compound with a range of potential applications.
Methoxypolyethylene glycol 750 is commonly known as Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, or mPEG.


Methoxypolyethylene glycol 750 is a versatile compound commonly used in various applications.
Also known as Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, and mPEG, Methoxypolyethylene glycol 750 has a range of potential uses.
With the CAS Number 9004-74-4 and the linear formula CH3(OCH2CH2)nOH, Methoxypolyethylene glycol 750 is available in powder form.


Methoxypolyethylene glycol 750 is used as a solvent, excipient, surfactant and dispersing agent.
Methoxypolyethylene glycol 750 is also used as a wetting agent and viscosity modifier.
Methoxypolyethylene glycol 750 finds application in the cosmetic and pharmaceutical industry due its low toxicity, lubricating property and solubility.


Due to its low toxicity Methoxypolyethylene glycol 750 can be used as a lubricating coating for various surfaces in aqueous and non-aqueous environments, a reagent in biochemistry to create very high osmotic pressures, a polar stationary phase for gas chromatography and as a binder.
Methoxypolyethylene glycol 750 is used as a pore-forming agent in the preparation of ultrafiltration membranes which are used in the removal of macromolecules.


Crystallization grade Methoxypolyethylene glycol 750 is used for formulating screens or for optimization.
Crystallization grade Methoxypolyethylene glycol 750 is used for formulating screens or for optimization
Methoxypolyethylene glycol 750 is a hydrophilic polymer that is used to control the flexibility of a composite.


Methoxypolyethylene glycol 750 can be used for a variety of applications such as drug delivery, tissue engineering, and other biological uses.
Unleash the power of the multi-functional Methoxypolyethylene glycol 750.
Methoxypolyethylene glycol 750, formulated to meet the varied demands of research and industry, enhances efficiency and assurances reproducible results, contributing to superior performance and success in all your endeavors.



ADAVANTAGES OF METHOXYPOLYETHYLENE GLYCOL 750:
*effective component of PCE type superplasticizing admixtures,
*very good hygroscopic properties,
*low diol content,
*paste/soft wax consistency,
*high solubility in water,
*slight odour,



STORAGE OF METHOXYPOLYETHYLENE GLYCOL 750:
Methoxypolyethylene glycol 750 with higher molecular weight is generally solid at room temperature and packed in slices.
Liquid Methoxypolyethylene glycol 750 is generally packed in 200kg iron or plastic barrels and transported as non dangerous goods.
Storage and cool and ventilated Methoxypolyethylene glycol 750 place, storage period 1 year



FEATURES OF METHOXYPOLYETHYLENE GLYCOL 750:
If the refined raw material and special catalyst are used, the impurity content of the product is low.
And the hydroxyl activity at the end of the molecular chain is retained to the greatest extent, with good hydrophilicity and hydroxyl reaction activity.



WHAT DOES METHOXYPOLYETHYLENE GLYCOL 750 DO IN A FORMULATION?
*Humectant



FEATURES AND BENEFITS OF METHOXYPOLYETHYLENE GLYCOL 750:
*Methoxypolyethylene glycol 750 is biodegradable, water-soluble polymer.
*Applications of Methoxypolyethylene glycol 750 include drug encapsulation and drug delivery.



KEY FEATURES OF METHOXYPOLYETHYLENE GLYCOL 750:
*Versatile compound with a range of potential uses
*Commonly used in various applications
*Also known as Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, and mPEG
*CAS Number: 9004-74-4
*Linear formula: CH3(OCH2CH2)nOH
*Available in powder form



INHERENT ADVANTAGES OF METHOXYPOLYETHYLENE GLYCOL 750:
*Superlative solubility in a variety of solvents including water, ethanol, acetone, and chloroform.
*Imperturbable stability under multiple conditions, enhancing the consistency of experimental results.
*User-friendly packaging - available in both bulk and prepack sizes, catering to diverse scale applications.
*The exceptional solubility and stability offered by Methoxypolyethylene glycol 750 make it invaluable for use across various sectors.
*Methoxypolyethylene glycol 750's superior stability facilitates reliable and reproducible results, which are fundamental in research and industrial operations.
*Methoxypolyethylene glycol 750's availability in different packaging formats allows custom scalability according to individual requirements.



SAFETY AND HANDLING OF METHOXYPOLYETHYLENE GLYCOL 750:
Methoxypolyethylene glycol 750 necessitates adherence to safety protocols.
Always follow the instructions provided in the Material Safety Data Sheet (MSDS) for a comprehensive understanding of safe handling, storage, and disposal procedures.



FEATURES METHOXYPOLYETHYLENE GLYCOL 750:
*Sterile filtered solution
*Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (


PHYSICAL and CHEMICAL PROPERTIES of METHOXYPOLYETHYLENE GLYCOL 750:
Molecular Formula: CH3O.(C2H4O)n.H
Molecular Weight: 700-800
CAS Number: 9004-74-4
EINECS/ELINCS: None
Appearance: White to light yellow paste
Melting Point: 52-56°C
Density at 25°C: 1.094 g/ml
Solubility in water: Soluble
Stability: Stable under ordinary conditions
Hydroxyl value: 70.0-80.0 mg KOH/g
Water content: 0.50% max
pH (1% solution): 5.0-7.0



FIRST AID MEASURES of METHOXYPOLYETHYLENE GLYCOL 750:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact: rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of METHOXYPOLYETHYLENE GLYCOL 750:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Take up dry.
Clean up affected area.



FIRE FIGHTING MEASURES of METHOXYPOLYETHYLENE GLYCOL 750:
-Extinguishing media:
*Suitable extinguishing media:
Water Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Special hazards arising from the substance or mixture:
Nature of decomposition products not known.



EXPOSURE CONTROLS/PERSONAL PROTECTION of METHOXYPOLYETHYLENE GLYCOL 750:
-Control parameters:
Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Safety glasses.
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of METHOXYPOLYETHYLENE GLYCOL 750:
-Conditions for safe storage, including any incompatibilities:
Storage conditions:
Tightly closed.
Dry.
Stored at room temperature.
But close the lid of the bottle tightly.
The product has a shelf life of at least 2 years.



STABILITY and REACTIVITY of METHOXYPOLYETHYLENE GLYCOL 750:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions: No data available


METHOXYPROPYLAMINE ( MOPA )
1-Amino-3-methoxypropane; 3-methoxy-1-Propanamine; 3-Methoxy-1-aminopropane; 3-Methoxypropane-1-amine; CAS NO:5332-73-0
METHYL 4-HYDROXYBENZOATE
Methyl 4-Hydroxybenzoate is a natural product found in Zanthoxylum beecheyanum, Rhizophora apiculata, and other organisms with data available.
Methyl 4-Hydroxybenzoate is also used as a food preservative and has the E number E218.


CAS Number: 99-76-3
EC Number: 202-785-7
MDL number: MFCD00002352
E number: E218 (preservatives)
Linear Formula: HOC6H4CO2CH3
Chemical formula: C8H8O3



Methyl 4-hydroxybenzoate, Methyl paraben, Methyl p-hydroxybenzoate, Methyl parahydroxybenzoate, Nipagin M, E number E218, Tegosept, Mycocten,
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Methyl 4-Hydroxybenzoate is slightly soluble in water.
Methyl 4-Hydroxybenzoate is incompatible with strong oxidizing agents and strong bases.
Methyl 4-Hydroxybenzoate must be suspended in ethanol first, since it does not dissolve readily in water.


Methyl 4-Hydroxybenzoate is indicated to have some pheromonal properties.
Methyl 4-Hydroxybenzoate is found in alcoholic beverages.
Methyl 4-Hydroxybenzoate is an antimicrobial agent, preservative, flavouring agent.


Methyl 4-Hydroxybenzoate is a constituent of cloudberry, yellow passion fruit, white wine, botrytised wine and Bourbon vanilla.
Methyl 4-Hydroxybenzoate has been shown to exhibit anti-microbial function.
Methyl 4-Hydroxybenzoate belongs to the family of Hydroxybenzoic Acid Derivatives.


These are compounds containing an hydroxybenzoic acid (or a derivative), which is a benzene ring bearing a carboxylic acid.
Methyl 4-Hydroxybenzoate is a 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol.
Methyl 4-Hydroxybenzoate is the most frequently used antimicrobial preservative in cosmetics.


Methyl 4-Hydroxybenzoate occurs naturally in several fruits, particularly in blueberries.
Methyl 4-Hydroxybenzoate has a role as a plant metabolite, an antimicrobial food preservative, a neuroprotective agent and an antifungal agent.
Methyl 4-Hydroxybenzoate one of the parabens, is a preservative with the chemical formula CH3(C6H4(OH)COO).


Methyl 4-Hydroxybenzoate is the methyl ester of p-hydroxybenzoic acid.
Methyl 4-Hydroxybenzoate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.


Methyl 4-Hydroxybenzoate is an organic chemical compound that is used as a preservative in pharmaceuticals, cosmetics and other industrial applications.
Methyl 4-Hydroxybenzoate is prepared by reacting benzoic acid with methanol.
Methyl 4-Hydroxybenzoate has been shown to induce apoptosis in human cancer cells by inhibiting the ryanodine receptor and controlling the release of calcium from intracellular stores.


Methyl 4-Hydroxybenzoate also has genotoxic activity which may be due to the reaction between methyl 4-hydroxybenzoate and p-hydroxybenzoic acid.
Methyl 4-Hydroxybenzoate has a high boiling point, which makes it difficult to dissolve in water.
Methyl 4-Hydroxybenzoate is a preservative with the chemical formula CH3(C6H4(OH)COO).


Methyl 4-Hydroxybenzoate, also called methyl paraben or nipagin, comprises the ester of p-hydroxybenzoic acid.
Methyl 4-Hydroxybenzoate is present naturally in cloudberry, white wine and bourbon vanilla.
Methyl 4-Hydroxybenzoate is a standardized methyl paraben allergen isolated from Yunnan hemlock (Tsuga dumosa).


Methyl 4-Hydroxybenzoate is an organic compound that has been used as a preservative in cosmetics, pharmaceuticals and food.
Methyl 4-Hydroxybenzoate is a member of the group of compounds known as parabens.
Methyl 4-Hydroxybenzoate can be prepared by the reaction of p-hydroxybenzoic acid with methyl alcohol.


The chemical formula for Methyl 4-Hydroxybenzoate is CH3CO2C6H4CH3.
Methyl 4-Hydroxybenzoate also shows genotoxic activity, which may be due to its ability to form intermolecular hydrogen bonding interactions with DNA or mRNA molecules.


The genotoxicity of Methyl 4-Hydroxybenzoate has been tested in vitro using bacterial strains and mammalian cells.
Methyl 4-Hydroxybenzoate also exhibits leukemia inhibitory factor (LIF) properties and may be useful for cancer therapy, although it needs more research to confirm this effect.



USES and APPLICATIONS of METHYL 4-HYDROXYBENZOATE:
Methyl 4-Hydroxybenzoate is an anti-fungal agent often used in a variety of cosmetics and personal-care products.
Methyl 4-Hydroxybenzoate is also used as a food preservative and has the E number E218.
Methyl 4-Hydroxybenzoate is commonly used as a fungicide in Drosophila food media at 0.1%.


Methyl 4-Hydroxybenzoate is used in allergenic testing.
The physiologic effect of Methyl 4-Hydroxybenzoate is by means of Increased Histamine Release, and Cell-mediated Immunity.
Methyl 4-Hydroxybenzoate is an excipient used as a preservative in foods, beverages and cosmetics.


Methyl 4-Hydroxybenzoate is used as a preservative in foods, beverages and cosmetics.
Methyl 4-Hydroxybenzoate is the methyl ester of p-hydroxybenzoic acid.
Methyl 4-Hydroxybenzoate can be used to inhibit yeast growth and can also be used as an antimicrobial agent for Gram-positive anaerobe


Methyl 4-Hydroxybenzoate is used as an anti-fungal agent.
Methyl 4-Hydroxybenzoate is also used as a preservative in foods, beverages and cosmetics.
Methyl 4-Hydroxybenzoate acts as an inhibitor of growth of molds and to lesser extent bacteria and as a vehicle for ophthalmic solution.


Methyl 4-Hydroxybenzoate is used as an anti-fungal agent.
Methyl 4-Hydroxybenzoate is also used as a preservative in foods, beverages and cosmetics.
Methyl 4-Hydroxybenzoate acts as an inhibitor of growth of molds and to lesser extent bacteria and as a vehicle for ophthalmic solution.


Methyl 4-Hydroxybenzoate has been used as an internal standard for the determination of trans-10-hydroxy-2-decenoic acid (10-HDA).
Methyl 4-Hydroxybenzoate is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Methyl 4-Hydroxybenzoate is used in the following products: cosmetics and personal care products, plant protection products and perfumes and fragrances.
Other release to the environment of Methyl 4-Hydroxybenzoate is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
Methyl 4-Hydroxybenzoate is used in the following products: plant protection products, pH regulators and water treatment products, laboratory chemicals and cosmetics and personal care products.


Methyl 4-Hydroxybenzoate is used in the following areas: agriculture, forestry and fishing, health services and scientific research and development.
Other release to the environment of Methyl 4-Hydroxybenzoate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.


Methyl 4-Hydroxybenzoate is used in the following products: cosmetics and personal care products.
Release to the environment of Methyl 4-Hydroxybenzoate can occur from industrial use: formulation of mixtures.
Methyl 4-Hydroxybenzoate is used in the following products: pH regulators and water treatment products and laboratory chemicals.


Methyl 4-Hydroxybenzoate is used in the following areas: health services and scientific research and development.
Methyl 4-Hydroxybenzoate is used for the manufacture of: chemicals.
Release to the environment of Methyl 4-Hydroxybenzoate can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.


Release to the environment of Methyl 4-Hydroxybenzoate can occur from industrial use: manufacturing of the substance.
Methyl 4-Hydroxybenzoate is also used in wastewater treatment plants as a coagulant to remove suspended solids.
Methyl 4-Hydroxybenzoate can be analyzed using plasma mass spectrometry, which separates compounds by their molecular weight and ionizes them before.


Methyl 4-Hydroxybenzoate is used as an anti-fungal agent.
Methyl 4-Hydroxybenzoate is also used as a preservative in foods, beverages and cosmetics.
Methyl 4-Hydroxybenzoate acts as an inhibitor of growth of molds and to lesser extent bacteria and as a vehicle for ophthalmic solution.


Methyl 4-Hydroxybenzoate has antimicrobial and antifungal functionality and is commercially used as a preservative in the food, cosmetic and pharmaceutical industry.
Methyl 4-Hydroxybenzoate has cytotoxic effects on keratinocytes in the presence of sunlight.


Methyl 4-Hydroxybenzoate upon solar irradiation mediates DNA damage and modulates esterase metabolism resulting in skin damage and favors cancer progression.
Methyl 4-Hydroxybenzoate has estrogenic functionality and upregulates estrogen-related genes.


Methyl 4-Hydroxybenzoate is used in sex-linked recessive lethal (SLRL) test in Drosophila melanogaster.
Methyl 4-Hydroxybenzoate is used as a constituent in cream formulation.
Methyl 4-Hydroxybenzoate is used as an antifungal agent in Drosophila melanogaster culture.


Methyl 4-Hydroxybenzoate is an antifungal that is widely used as a preservative found in food, drugs, and cosmetics.
Methyl 4-Hydroxybenzoate is commonly used as a stable, non-volatile preservative.
Methyl 4-Hydroxybenzoate increases histamine release and cellular regulation of immunity, blocks sodium channels, and prevents ischemia-reperfusion injury.



NATURAL ACCURRENCES OF METHYL 4-HYDROXYBENZOATE:
Methyl 4-Hydroxybenzoate serves as a pheromone for a variety of insects and is a component of queen mandibular pheromone.
Methyl 4-Hydroxybenzoate is a pheromone in wolves produced during estrus associated with the behavior of alpha male wolves preventing other males from mounting females in heat.



PHYSICAL and CHEMICAL PROPERTIES of METHYL 4-HYDROXYBENZOATE:
Chemical formula:C8H8O3
Molar mass: 152.149 g·mol−1
Appearance: Colorless crystals or white crystalline powder
UV-vis (λmax): 255 nm (methanol)
Magnetic susceptibility (χ): −88.7·10−6 cm3/mol
CAS Number: 99-76-3
Molecular Weight: 152.15
Beilstein: 509801
EC Number: 202-785-7
MDL number: MFCD00002352
Physical state: crystalline
Color: white
Odor: odorless
Melting point/freezing point:
Melting point/range: 125 - 128 °C - lit.
Initial boiling point and boiling range: Decomposes below the boiling point.

Flammability (solid, gas): The product is not flammable.
Flammability (solids)
Upper/lower flammability or explosive limits: No data available
Flash point: 168 °C
Autoignition temperature: > 403 °C
- Relative self-ignition temperature for solids
Decomposition temperature: 270 - 280 °C
pH: 5,72 at 1,88 g/l at 20 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 1,88 g/l at 20 °C
Partition coefficient: n-octanol/water:
Pow: 95,5; log Pow: 1,98 at 22 °C

Vapor pressure < 1 hPa at 20 °C
Density: 1,38 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Relative vapor density: 5,23 - (Air = 1.0)
CAS number: 99-76-3
EC number: 202-785-7
Grade: Ph Eur,BP,JP,NF
Hill Formula: C₈H₈O₃
Chemical formula: 4-(OH)C₆H₄(COOCH₃)
Molar Mass: 152.15 g/mol

HS Code: 2918 29 00
Density: 1.38 g/cm3 (20 °C)
Flash point: 168 °C Not applicable
Ignition temperature: >600 °C
Melting Point: 125 °C
pH value: 5.72 (1.88 g/l, H₂O, 20 °C) (saturated solution)
Vapor pressure: Bulk density: 300 - 400 kg/m3
Solubility: 1.88 g/l
Molecular Weight: 152.15 g/mol
XLogP3: 2
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 2
Exact Mass: 152.047344113 g/mol
Monoisotopic Mass: 152.047344113 g/mol

Topological Polar Surface Area: 46.5Ų
Heavy Atom Count: 11
Formal Charge: 0
Complexity: 136
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Melting Point: 125 - 128 Deg C
Grade: USP Grade
Heavy metals: Loss on Drying: <0.5%
Storage Temperature: +20 ° C

Molecular Weight: 152.15
Residue on Ignition: <0.1%
Residual Solvents: Sulfated ash: <0.05%
Appearance: White powder
PH value: 5.0 - 6.0
Assay (on dried basis): 99 - 100.5%
Microbial count: <100cfu
IUPAC Name: methyl 4-hydroxybenzoate
Molecular Weight: 152.15
Molecular Formula: C8H8O3
Canonical SMILES: COC(=O)C1=CC=C(C=C1)O
InChI: InChI=1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3
InChIKey: LXCFILQKKLGQFO-UHFFFAOYSA-N
Boiling Point: 265.5 °C at 760 mmHg
Melting Point: 124-129 °C
Flash Point: 116.4ºC

Purity: 98.5%
Density: 1.209 g/cm3
Solubility: Soluble in DMSO (slightly), methanol (slightly).
Appearance: White solid
Storage: Cool and dry place.
Hazard Codes: Xi; Xn
HS Code: 2918290000
Log P: 1.17880
MDL: MFCD00002352
PSA: 46.53
Refractive Index: 1.5204 (137ºC)
RIDADR: UN 2769
Risk Statements: R36/37/38
RTECS: DH2450000
Safety Statements: S24/25
Stability: Stable.
Incompatible with strong oxidizing agents, strong bases.
Vapor Pressure: 2.37X10-4 mm Hg at 25 °C (est)

Melting Point: 124°C to 131°C
Boiling Point: 270°C to 280°C
Solubility Information: Slightly soluble in water (1g/400mL);
soluble in warm oil (1g/40mL) or warm glycerol (1g/70mL);
freely soluble in alcohol (50mg/mL methanol, clear, colorless solution),
acetone or ether.
Formula Weight: 152.1
Physical Form: Crystalline Powder
Molecular Formula / Molecular Weight: C8H8O3 = 152.15
Physical State (20 deg.C): Solid
Store Under Inert Gas: Store under inert gas
Condition to Avoid: Air Sensitive
CAS RN: 99-76-3
Reaxys Registry Number: 509801
PubChem Substance ID: 87570645
SDBS (AIST Spectral DB): 2537
Merck Index (14): 6107
MDL Number: MFCD00002352



FIRST AID MEASURES of METHYL 4-HYDROXYBENZOATE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of METHYL 4-HYDROXYBENZOATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of METHYL 4-HYDROXYBENZOATE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of METHYL 4-HYDROXYBENZOATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Respiratory protection:
Recommended Filter type: Filter type P1
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of METHYL 4-HYDROXYBENZOATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
*Storage class:
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of METHYL 4-HYDROXYBENZOATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available

METHYL ACETATE
DESCRIPTION:

Methyl acetate, also known as MeOAc, acetic acid methyl ester or methyl ethanoate, is a carboxylate ester with the formula CH3COOCH3.
Methyl acetate is a flammable liquid with a characteristically pleasant smell reminiscent of some glues and nail polish removers.
Methyl acetate is occasionally used as a solvent, being weakly polar and lipophilic, but its close relative ethyl acetate is a more common solvent being less toxic and less soluble in water.

CAS Number: 79-20-9
European Community (EC) Number: 201-185-2
Molecular Formula: C3H6O2

Methyl acetate has a solubility of 25% in water at room temperature.
At elevated temperature its solubility in water is much higher.
Methyl acetate is not stable in the presence of strong aqueous bases or aqueous acids. Methyl acetate is not considered a VOC in the USA.

Methyl acetate appears as a clear colorless liquid with a fragrant odor.
Methyl acetate is Moderately toxic.
Flash point of Methyl acetate is 14 °F.
Vapors of Methyl acetate is heavier than air.


Methyl acetate is an acetate ester resulting from the formal condensation of acetic acid with methanol.
A low-boiling (57 ℃) colourless, flammable liquid, Methyl acetate is used as a solvent for many resins and oils.
Methyl acetate has a role as a polar aprotic solvent, a fragrance and an EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor.

Methyl acetate is an acetate ester, a methyl ester and a volatile organic compound.
Methyl acetate is a natural product found in Peristeria elata, Coffea arabica, and other organisms with data available.


Methyl acetate (also known as methyl ethanoate, acetic acid methyl ester, MeOAc, Tereton, Devoton) is a carboxylate ester with a molecular formula of C3H6O2.
Methyl acetate is a clear, colourless liquid that has a typical ester odour similar to glues and nail polish removers.
Methyl acetate is very flammable with a flashpoint of -10° C and a flammability rating of 3.
Methyl acetate is commonly used in low toxicity solvents such as glues, nail polish removers.


Methyl acetate is highly miscible with all common organic solvents (alcohols, ketones, glycols, esters) but has only slight miscibility in water, but becomes more soluble in water with elevated temperatures.
Methyl acetate is commonly found in fruits such as apples, grapes and bananas.

Methyl acetate (MA) is an aliphatic ester that can be prepared via carbonylation of dimethyl ether over zeolites.
Methyl acetate is formed as a by-product during the preparation of polyvinyl alcohol from acetic acid and methanol.



PRODUCTION OF METHYL ACETATE:
There are various methods of producing methyl acetate.
One that is used industrially is via carbonylation.
These types of reactions bring together carbon monoxide substrates.

To produce methyl acetate, methanol is heated alongside acetic acid in the presence of sulfuric acid.
Another method of production is the esterification of methanol and acetic acid in the presence of a strong acid.
Sulfuric acid is a common catalyst also used in this reaction.


PREPARATION AND REACTIONS OF METHYL ACETATE:
Methyl acetate is produced industrially via the carbonylation of methanol as a byproduct of the production of acetic acid.
Methyl acetate also arises by esterification of acetic acid with methanol in the presence of strong acids such as sulfuric acid; this production process is famous because of Eastman Kodak's intensified process using a reactive distillation.

REACTIONS OF METHYL ACETATE:
In the presence of strong bases such as sodium hydroxide or strong acids such as hydrochloric acid or sulfuric acid it is hydrolyzed back into methanol and acetic acid, especially at elevated temperature.
The conversion of methyl acetate back into its components, by an acid, is a first-order reaction with respect to the ester.
The reaction of methyl acetate and a base, for example sodium hydroxide, is a second-order reaction with respect to both reactants.

Methyl acetate is a Lewis base that forms 1:1 adducts with a variety of Lewis acids.
Methyl acetate is classified as a hard base and is a base in the ECW model with EB =1.63 and CB = 0.95.

APPLICATIONS OF METHYL ACETATE:
A major use of methyl acetate is as a volatile low toxicity solvent in glues, paints, and nail polish removers.
Acetic anhydride is produced by carbonylation of methyl acetate in a process that was inspired by the Monsanto acetic acid synthesis.

Methyl acetate may be used for the preparation of fatty acid methyl esters and triacetin from rapeseed oil via non-catalytic trans-esterification reaction under super-critical conditions.

Methyl acetate is used in Adhesives/sealants-B&C
Methyl acetate is used in Aerosol coatings
Methyl acetate is used in Architectural coatings


Methyl acetate is used in Auto OEM
Methyl acetate is used in Auto refinish
Methyl acetate is used in Automotive

Methyl acetate is used in Commerical printing inks
Methyl acetate is used in Construction chemicals
Methyl acetate is used in General industrial coatings

Methyl acetate is used in Graphic arts
Methyl acetate is used in Intermediates
Methyl acetate is used in Marine

Methyl acetate is used in Paints & coatings
Methyl acetate is used in Pharmaceutical chemicals
Methyl acetate is used in Protective coatings
Methyl acetate is used in Wood coatings





USES OF METHYL ACETATE:
Industry Uses:
Industry uses of methyl ethanoate involve the reaction of carbonylation to produce acetic anhydride.
Methyl acetate is also used in paint and coating adhesives, lubricants, intermediates, processing aids and as a solvent in paint, glue, nail polish and graffiti removers.

Methyl ethanoate is also used as a chemical intermediate for the synthesis of chlorophacinone, diphacinone, fenfluramine, o-methoxyphenylacetone, p-methoxyphenylacetone, methyl cinnamate, methyl cyanoacetate, methyldopa, and phenylacetone and in the manufacturing of cellulose adhesives and perfumes.

Commercial Uses:
Methyl ethanoate is used commercially as a flavouring agent in food additives for rum, brandy, whisky, in adhesives, cleaning products, personal care and cosmetic products, lubricants, fast-paced drying paints such as lacquers, motor vehicle coatings, furniture coatings, industrial coatings (low boiling point) inks, resins, oils artificial leathers and electronic products.
The main user end markets for Methyl acetate are the paint, coatings, cosmetic, textiles and motor industries.








CHEMICAL AND PHYSICAL PROPERTIES OF METHYL ACETATE:
Chemical formula C3H6O2
Molar mass 74.079 g•mol−1
Appearance Colorless liquid
Odor Fragrant, fruity
Density 0.932 g cm−3
Melting point −98 °C (−144 °F; 175 K)
Boiling point 56.9 °C (134.4 °F; 330.0 K)
Solubility in water ~25% (20 °C)
Vapor pressure 173 mmHg (20°C)
Magnetic susceptibility (χ) -42.60•10−6 cm3/mol
Refractive index (nD) 1.361
Molecular Weight
74.08 g/mol
XLogP3
0.2
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
1
Exact Mass
74.036779430 g/mol
Monoisotopic Mass
74.036779430 g/mol
Topological Polar Surface Area
26.3Ų
Heavy Atom Count
5
Formal Charge
0
Complexity
40.2
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
CAS number 79-20-9
EC index number 607-021-00-X
EC number 201-185-2
Hill Formula C₃H₆O₂
Chemical formula CH₃COOCH₃
Molar Mass 74.08 g/mol
HS Code 2915 39 39
Boiling point 56 - 58 °C (1013 hPa)
Density 0.934 g/cm3 (25 °C)
Explosion limit 3.1 - 16 %(V)
Flash point -13 °C
Ignition temperature 455 °C
Melting Point -98 °C
Vapor pressure 228 hPa (20 °C)
Solubility 250 g/l
Assay (GC, area%) ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C) 0.932 - 0.934
Identity (IR) passes test
Molecular Formula: C3H6O2 / CH3COOCH3
Synonyms: methyl ethanoate, acetic acid methyl ester, MeOAc, tereton, devoton, methyl ester of acetic acid, methylacetate
Cas Number: 79-20-9
Molecular Mass: 74.079 g•mol−1
Exact Mass: 74.036779 g/mol
Flashpoint: 14 °F / -10 °C
Boiling Point: 134.4 °F at 760 mm Hg / 56.8 °C
Melting Point: -144 °F / -98.0 °C
Vapour Pressure: 170 mm Hg at 68 ° F ; 235 mm Hg at 77° F
Water Solubility: ~25% (20 °C)
Density: 0.932 g cm−3
Log P: 0.18
grade
anhydrous
Quality Level
100
vapor density
2.55 (vs air)
vapor pressure
165 mmHg ( 20 °C)
Assay
99.5%
form
liquid
autoignition temp.
936 °F
expl. lim.
16 %





SAFETY INFORMATION ABOUT METHYL ACETATE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product




SYNONYMS OF METHYL ACETATE:
acetic acid methyl ester
methyl acetate
METHYL ACETATE
79-20-9
Methyl ethanoate
Tereton
Acetic acid, methyl ester
Devoton
Acetic acid methyl ester
Methylacetat
Acetate de methyle
Methylacetaat
Methyl acetic ester
Octan metylu
Metile (acetato di)
Methyle (acetate de)
Methylester kiseliny octove
Ethyl ester of monoacetic acid
HSDB 95
Methylacetat [German]
FEMA No. 2676
CH3COOCH3
MeOAc
Methyl ester of acetic acid
NSC 405071
METHYL-ACETATE
ACETIC ACID,METHYL ESTER
DTXSID4021767
CHEBI:77700
W684QT396F
NSC-405071
Methylacetat (german)
NCGC00090940-01
Acetic acid-methyl ester
DTXCID101767
Methylacetaat [Dutch]
Octan metylu [Polish]
FEMA Number 2676
Methyl acetate (natural)
CAS-79-20-9
Methyl Acetate; Acetic acid methyl ester
Acetate de methyle [French]
CCRIS 5846
Methyle (acetate de) [French]
Metile (acetato di) [Italian]
Methylester kiseliny octove [Czech]
EINECS 201-185-2
UN1231
Metile
METHYL ACETATE, 97%
UNII-W684QT396F
AcOMe
1-Methyl acetate
CH3COOMe
Methyl acetate [UN1231] [Flammable liquid]
CH3CO2CH3
EC 201-185-2
METHYL ACETATE [MI]
METHYL ACETATE [FCC]
WLN: 1VO1
CHEMBL14079
METHYL ACETATE [FHFI]
METHYL ACETATE [HSDB]
METHYL ACETATE [INCI]
Methyl acetate, >=98%, FG
METHYL ACETATE [USP-RS]
FEMA 2676
Methyl acetate, analytical standard
Methyl acetate, anhydrous, 99.5%
Methyl acetate, natural, 98%, FG
Tox21_113243
Tox21_200057
Methyl acetate, reagent grade, 95%
MFCD00008711
NSC405071
STL281977
AKOS000120042
Methyl acetate, ReagentPlus(R), 99%
UN 1231
Methyl acetate, for HPLC, >=99.8%
NCGC00090940-02
NCGC00257611-01
FT-0621748
S0300
EN300-15476
Methyl acetate, SAJ first grade, >=99.0%
C17530
Methyl acetate [UN1231] [Flammable liquid]
Methyl acetate, JIS special grade, >=99.5%
InChI=1/C3H6O2/c1-3(4)5-2/h1-2H
A839618
Q414189
J-522583
Acetic acid-methyl ester 1000 microg/mL in Methanol
Methyl acetate, United States Pharmacopeia (USP) Reference Standard



METHYL ACETATE
Methyl Acetate Methyl acetate, also known as MeOAc, acetic acid methyl ester or methyl ethanoate, is a carboxylate ester with the formula CH3COOCH3. Methyl acetate is a flammable liquid with a characteristically pleasant smell reminiscent of some glues and nail polish removers. Methyl acetate is occasionally used as a solvent, being weakly polar and lipophilic, but its close relative ethyl acetate is a more common solvent being less toxic and less soluble in water. Methyl acetate has a solubility of 25% in water at room temperature. At elevated temperature its solubility in water is much higher. Methyl acetate is not stable in the presence of strong aqueous bases or aqueous acids. Methyl acetate is not considered a VOC in the USA. Preparation and reactions of Methyl acetate Methyl acetate is produced industrially via the carbonylation of methanol as a byproduct of the production of acetic acid.[6] Methyl acetate also arises by esterification of acetic acid with methanol in the presence of strong acids such as sulfuric acid; this production process is famous because of Eastman Kodak's intensified process using a reactive distillation. Reactions of Methyl acetate In the presence of strong bases such as sodium hydroxide or strong acids such as hydrochloric acid or sulfuric acid it is hydrolyzed back into methanol and acetic acid, especially at elevated temperature. The conversion of methyl acetate back into its components, by an acid, is a first-order reaction with respect to the ester. The reaction of methyl acetate and a base, for example sodium hydroxide, is a second-order reaction with respect to both reactants. Methyl acetate is a Lewis base that forms 1:1 adducts with a variety of Lewis acids. It is classified as a hard base and is a base in the ECW model with EB =1.63 and CB = 0.95. Applications of Methyl acetate A major use of methyl acetate is as a volatile low toxicity solvent in glues, paints, and nail polish removers. Acetic anhydride is produced by carbonylation of methyl acetate in a process that was inspired by the Monsanto acetic acid synthesis. General description of Methyl acetate Methyl acetate (MA) is an aliphatic ester that can be prepared via carbonylation of dimethyl ether over zeolites.[7] Methyl acetate is formed as a by-product during the preparation of polyvinyl alcohol from acetic acid and methanol.[8] Application of Methyl acetate Methyl acetate may be used for the preparation of fatty acid methyl esters and triacetin from rapeseed oil via non-catalytic trans-esterification reaction under super-critical conditions.[9] Packaging of Methyl acetate 1, 2 L in Sure/Seal™ 100 mL in Sure/Seal Methyl acetate appears as a clear colorless liquid with a fragrant odor. Moderately toxic. Flash point 14°F. Vapors heavier than air. Methyl acetate is an acetate ester resulting from the formal condensation of acetic acid with methanol. A low-boiling (57 ℃) colourless, flammable liquid, it is used as a solvent for many resins and oils. It has a role as a polar aprotic solvent, a fragrance and an EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor. It is an acetate ester, a methyl ester and a volatile organic compound. Methyl acetate is a waste chemical stream constituent which may be subjected to ultimate disposal by controlled incineration. The following wastewater treatment technologies have been investigated for methyl acetate: Concentration process: Reverse osmosis. EXCESS METHYL ACETATE IN WASTE GASES CAN BE REMOVED BY CATALYTIC OXIDATION. Absorption, Distribution and Excretion of Methyl acetate After oral administration to rabbits, methyl acetate was hydrolysed to methanol and acetic acid. The animals received a dosage of 20 mL/kg bw of a 5% aqueous solution (1,000 mg/kg). Methanol concentration was analysed in the blood from 30 minutes after application up to 5 hours. Methyl acetate could not be detected in any sample whereas methanol was found in blood and urine already after 30 min. Peak concentrations of methanol in the blood were measured after 3 hours and amounted to 0.573 mg/mL. Following oral application methyl acetate is hydrolysed in the gut. Therefore, in blood and urine only methanol and acetic acid were found, not methyl acetate. Similarly, after inhalation exposure in blood and urine only the products of hydrolysis were detectable. After oral exposure methyl acetate is partially cleaved in the gastrointestinal tract into methanol and acetic acid by esterases of the gastric mucosa. The ester is furthermore hydrolysed by esterases of the blood. Similarly, after inhalation exposure of rats to a concentration of 2,000 ppm (6,040 mg/cu m) blood concentrations less than 4.6 mg/L were determined. ... Inhalation exposure at saturation conditions results in the occurrence of methyl acetate in blood. Biotransformation of methyl acetate takes place by rapid hydrolysis of the compound into methanol and acetic acid by the nonspecific carboxylic esterases in the blood and tissues. With human subjects /it has been shown/ that metabolic hydrolysis of methyl acetate to methanol and acetic acid proceeds directly proportional to exposure level. Biological Half-Life of Methyl acetate For the in vitro hydrolysis of methyl acetate in blood of rats /a/ half-life of 2-3 hr was determined indicating a rapid hydrolysis in the blood. For the in vitro hydrolysis of methyl acetate in blood of humans, /a/ half-life of about 4 hr was determined. Commonly sold in combination with methanol in an 80/20 methyl acetate/methanol by-product blend Overview of Methyl acetate IDENTIFICATION: Methyl acetate is a colorless volatile liquid. It has a pleasant fruity odor. The vapor is heavier than air. It will dissolve in water. USE: Methyl acetate is used in paint remover compounds and solvents. It is used to make other chemicals. It is used as an imitation fruit flavoring. EXPOSURE: Workers in the paint industry and paper mills may be exposed to methyl acetate. People may be exposed to methyl acetate by breathing in air when using paint remover or eating foods containing methyl acetate as a flavor ingredient. Methyl acetate occurs naturally in mint, fungus, Kiwi fruit, grapes, and bananas. If methyl acetate is released to the environment, it will break down in air. It will move down through soil. It will volatilize from soil and water. Methyl acetate is very soluble in water. It appears to be rapidly broken down by microorganisms in soil and water. It does not build up in aquatic organisms. RISK: Methyl acetate is absorbed by the respiratory system and by the skin. In the body, methyl acetate is rapidly converted to methanol. Eye irritation has been reported in furniture polishers exposed to paint thinners containing methyl acetate and other solvents. Recurrent dizziness, headaches, fatigue, faintness, staggering and blindness occurred in a worker exposed to vapors of methyl acetate in an enclosed space. Very high exposure may result in unconsciousness and death. These effects are consistent with the toxic effects of methanol. Eye irritation and skin damage have been observed in laboratory animals following application of methyl acetate to the eyes or skin. Methyl acetate has not been tested for cancer, developmental or reproductive effects in laboratory animals. The potential for methyl acetate to cause cancer in humans has not been assessed by the U.S. EPA IRIS program, the International Agency for Research on Cancer, or the U.S. National Toxicology Program 12th Report on Carcinogens. Storage Conditions of Methyl acetate Store in a flammable liquid storage area or approved cabinet away from ignition sources and corrosive and reactive materials. ... Methyl acetate must be stored to avoid contact with strong oxidizers (such as chlorine, bromine, and fluorine) and strong acids (such as hydrochloric, sulfuric, and nitric), since violent reactions occur. Store in tightly closed containers in a cool, well-ventilated area away from strong alkalis and nitrates. Sources of ignition, such as smoking and open flames, are prohibited where methyl acetate is used, handled or stored in a manner that could create a potential fire or explosion hazard. Use only nonsparking tools and equipment, especially when opening and closing containers of methyl acetate. Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Moisture sensitive. Reactivity Profile of Methyl acetate METHYL ACETATE presents a fire or explosion hazard when exposed to strong oxidizing agents. Emits irritating fumes and acrid smoke when heated to decomposition, [Lewis, 3rd ed., 1993, p. 826]. Its reactivity is consistent with other compounds of the ester group. For more DOT Emergency Guidelines (Complete) data for METHYL ACETATE (8 total), please visit the HSDB record page. This action promulgates standards of performance for equipment leaks of Volatile Organic Compounds (VOC) in the Synthetic Organic Chemical Manufacturing Industry (SOCMI). The intended effect of these standards is to require all newly constructed, modified, and reconstructed SOCMI process units to use the best demonstrated system of continuous emission reduction for equipment leaks of VOC, considering costs, non air quality health and environmental impact and energy requirements. Methyl acetate is produced, as an intermediate or final product, by process units covered under this subpart. Pursuant to section 8(d) of TSCA, EPA promulgated a model Health and Safety Data Reporting Rule. The section 8(d) model rule requires manufacturers, importers, and processors of listed chemical substances and mixtures to submit to EPA copies and lists of unpublished health and safety studies. Methyl acetate is included on this list. Effective date: 1/26/94; Sunset date: 6/30/98. Methyl acetate is a food additive permitted for direct addition to food for human consumption as a synthetic flavoring substance and adjuvant in accordance with the following conditions: a) they are used in the minimum quantity required to produce their intended effect, and otherwise in accordance with all the principles of good manufacturing practice, and 2) they consist of one or more of the following, used alone or in combination with flavoring substances and adjuvants generally recognized as safe in food, prior-sanctioned for such use, or regulated by an appropriate section in this part. Methyl acetate is an indirect food additive for use only as a component of adhesives. At high concentrations, methyl acetate may cause mild to severe methanol intoxication form ingestion, inhalation, or possible skin contact. The vapor is mildly irritant to the eyes and respiratory system and at high concentrations can cause CNS depression. IDENTIFICATION AND USE: Methyl Acetate is a colorless, volatile liquid, which is used as a solvent for nitrocellulose, acetylcellulose; in many resins and oils and in the manufacture of artificial leather. It is also used in paint remover compounds, lacquer solvent, intermediate, and synthetic flavoring. HUMAN EXPOSURE AND TOXICITY: The vapor is mild irritant to the eyes and respiratory system and at high concentrations can cause CNS depression. Accidental human exposure to methyl acetate vapor for 45 minutes resulted in severe headache and somnolence lasting about 6 hr. In another case report, a teenage girl experienced acute blindness following inhalation of vapor from lacquer thinner. It was determined that methanol and methyl acetate vapors caused optic neuropathy that led to the blindness. At high concentrations, methyl acetate may cause mild to severe methanol intoxication from ingestion, inhalation, or possible skin contact. ANIMAL STUDIES: Inhalation exposure of 4 rats to a saturated atmosphere of methyl acetate (in 25 L bottles) induced narcotic effects in the animals after 10 to 20 min. After decapitation at this time-point concentrations of 70-80 mg methyl acetate/100 mL were found in the blood. Similar experiments with inhalation exposure to methanol showed that the narcotic effects are mainly induced by methyl acetate. Cats exposed to 10,560 ppm methyl acetate vapor suffered from irritation of the eyes and salivation. Rats were exposed (at 10,000 ppm in ambient air) to a thinner containing methyl acetate (12.6%) in a plastic container for 10 min at 10 min intervals (2 times/day, 6 days/wk, for 12-14 mo). Body weight gain was suppressed compared to controls. Electron microscopic exam of slices of the cerebral cortex showed increased abnormal cristae of mitochondria in the neurons and axons and increased number of endoplasmic reticula and ribosomes and dilated Golgi apparatus in the neurons. Increased lysosomes and lipid materials were observed in neurons, suggesting a degenerative process. Methyl acetate did not produce an increase in revertants in Salmonella typhimurium strains TA 98, TA 100, TA 1535, TA 1537 and TA 1538, and Escherichia coli WP2uvrA, in the absence or presence of metabolic activation. Methyl acetate was tested up to 5,000 ug/plate. Negative results were obtained in a study using Salmonella typhimurium strains TA97, TA98, TA100, TA1535 and TA1538 with or without metabolic activation system, when tested up to 10,000 ug/plate. This study employed a 20-minute preincubation period. Biotransformation of methyl acetate takes place by rapid hydrolysis of the compound into methanol and acetic acid by the nonspecific carboxylic esterases in the blood and tissues. /HUMAN EXPOSURE STUDIES/ Respiratory uptake was investigated for 10 polar organic solvents with high blood/air partition coefficients (lambda(blood/air)): ethyl acetate (lambda(blood/air), 77), methyl iso-butyl ketone (90), methyl acetate (90), methyl propyl ketone (150), acetone (245), iso-pentyl alcohol (381), iso-propyl alcohol (848), methyl alcohol (2590), ethylene glycol monobutyl ether (EGBE, 7970), and propylene glycol monomethyl ether (PGME, 12380). Test-air concentrations (Cinh) were 25 to 200 ppm. Four healthy male volunteers inhaled the test air for 10 min at rest and then room air for 5 min. The percentage of solvent in the end-exhaled air and in the mixed-exhaled air increased after the start of the test-air respiration, and reached a quasi-steady-state level within a few min. The speeds of these increases at the start of the test-air respiration became lower as lambda(blood/air) increased. The mean uptakes (U) for the last five min of the test air respiration were 67.3, 52.9, 60.4, 53.0, 52.6, 63.0, 60.3, 60.8, 79.7, and 81.3%, respectively, for ethyl acetate, methyl iso-butyl ketone, methyl acetate, methyl propyl ketone, acetone, iso-pentyl alcohol, iso-propyl alcohol, methyl alcohol, EGBE and PGME. Thus, U values of the alcohols were higher than those of the ketones and lower than the glycol ethers. The overall view, except for esters, showed that U increased with lambda(water/air) increases. This tendency can be explained by a hypothesis that solvent absorbed in the mucus layer of the respiratory tract is removed by the bronchial blood circulation. U values of ethyl acetate and methyl acetate were higher than those of methyl iso-butyl ketone and methyl propyl ketone, though the lambda(blood/air) values of these esters were nearly equal to those of the ketones. For the respiration of the esters, their metabolites, ethyl alcohol and methyl alcohol, were detected in the exhaled air. The exhalation percentage of the metabolites increased after the start of test-air respiration and reached a quasi-steady-state level of 2 and 3%, respectively, by the 5th min. These data suggest that removal of the solvent via metabolism in the wall tissue of the respiratory tract plays an important role for the esters. Women working in a shoe-factory suffered from eye irritation, visual disorders, CNS symptoms, difficulties of breathing and heart trouble and identified a liquid mixture of methylformate, ethylformate, ethyl acetate and methyl acetate. Acute Exposure/ Inhalation exposure of 4 rats to a probably saturated atmosphere of methyl acetate (in 25 L bottles) induced /CNS depressant/ effects in the animals after 10 to 20 min. After decapitation at this time-point concentrations of 70-80 mg methyl acetate/100 mL were found in the blood. Similar experiments with inhalation exposure to methanol showed that the narcotic effects are mainly induced by methyl acetate. Acute Exposure/ Cats exposed to /inhalation of methyl acetate/ 53,790 ppm for 14-18 min /showed/ irritation, salivation, dyspnea, convulsions in 50%, /CNS depression/, lethal in 1-9 min, later with diffuse pulmonary edema. 34,980 ppm for 29-30 min /produced/ irritation, salivation, dyspnea, convulsions in 50%, narcosis, histology: lateral emphysema or edema. /From table/ Acute Exposure/ Cats exposed to /inhalation of methyl acetate/ 18480 ppm for 4 to 4.5 hr showed eye irritation, dyspnea, vomiting and convulsions in 50%, /CNS depression/, slow recovery; at 9900 ppm for 10 hr, eye irritation, salivation, somnolence, recovery;at 5000 ppm for 20 min, eye irritation and salivation. /From table/ Environmental Fate/Exposure Summary Methyl acetate's production and use as a solvent for nitrocellulose, acetylcellulose, resins and oils, in the manufacture of artificial leather; as a catalyst for the biodegradation of organic materials; as a flavoring agent useful in rum, brandy, whiskey; and as a chemical intermediate may result in its release to the environment through various waste streams. Methyl acetate occurs naturally in mint, fungus, grapes, bananas and coffee. If released to air, a vapor pressure of 216.2 mm Hg at 25 °C indicates methyl acetate will exist solely as a vapor in the atmosphere. Vapor-phase methyl acetate will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 41 days. Methyl acetate does not contain chromophores that absorb at wavelengths >290 nm and, therefore, is not expected to be susceptible to direct photolysis by sunlight. If released to soil, methyl acetate is expected to have very high mobility based upon an estimated Koc of 9.1. Volatilization from moist soil surfaces is expected to be an important fate process based upon a measured Henry's Law constant of 1.15X10-4 atm-cu m/mole. Methyl acetate may volatilize from dry soil surfaces based upon its vapor pressure. Methyl acetate achieved >70% after 28 days in an OECD 301D Closed bottle test, suggesting that biodegradation is an important environmental fate process in soil and water. If released into water, methyl acetate is not expected to adsorb to suspended solids and sediment based upon the estimated Koc. Volatilization from water surfaces is expected to be an important fate process based upon this compound's Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 5 hours and 5 days, respectively. An estimated BCF of 3 suggests the potential for bioconcentration in aquatic organisms is low. Hydrolysis half-lives for methyl acetate were 1.7 years and 63 days at pH values of 7 and 8. Occupational exposure to methyl acetate may occur through inhalation and dermal contact with this compound at workplaces where methyl acetate is produced or used. Monitoring and use data indicate that the general population may be exposed to methyl acetate via inhalation of ambient air and ingestion of food and dermal contact with consumer products containing methyl acetate. Methyl acetate may be released to the environment from natural sources. It has been detected as a volatile constituent of nectarines(1,3) and Kiwi fruit flowers(2). Methyl acetate occurs naturally in mint, fungus, grapes and bananas(3). Methyl acetate's production and use as a solvent for nitrocellulose, acetylcellulose, resins and oils, in the manufacture of artificial leather(1); as a catalyst for the biodegradation of organic materials(2); as a flavoring agent useful in rum, brandy, whiskey(3); and as a chemical intermediate(4) may result in its release to the environment through various waste streams(SRC). TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 9.1(SRC), determined from a log Kow of 0.18(2) and a regression-derived equation(3), indicates that methyl acetate is expected to have very high mobility in soil(SRC). Volatilization of methyl acetate from moist soil surfaces is expected to be an important fate process(SRC) given a measured Henry's Law constant of 1.15X10-4 atm-cu m/mole(4). Methyl acetate is expected to volatilize from dry soil surfaces(SRC) based upon an measured vapor pressure of 216.2 mm Hg at 25 °C(5). Methyl acetate achieved >70% after 28 days in an OECD 301D Closed bottle test(6), suggesting that biodegradation is an important environmental fate process in soil(SRC). AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 9.1(SRC), determined from a log Kow of 0.18(2) and a regression-derived equation(3), indicates that methyl acetate is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(4) based upon a measured Henry's Law constant of 1.15X10-4 atm-cu m/mole(5). Using this Henry's Law constant and an estimation method(4), volatilization half-lives for a model river and model lake are 5 hours and 5 days, respectively(SRC). According to a classification scheme(6), an estimated BCF of 3(SRC), from its log Kow(2) and a regression-derived equation(3), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Methyl acetate achieved >70% after 28 days in an OECD 301D Closed bottle test(7), suggesting that biodegradation is an important environmental fate process in water(SRC). ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), methyl acetate, which has a vapor pressure of 216.2 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase methyl acetate is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 41 days(SRC), calculated from its rate constant of 2.6X10-13 cu cm/molecule-sec at 25 °C(3). Methyl acetate does not contain chromophores that absorb at wavelengths >290 nm(4) and, therefore, is not expected to be susceptible to direct photolysis by sunlight(SRC). AEROBIC: Methyl acetate achieved >70% after 28 days in an OECD 301D Closed bottle test(1). Methyl acetate reached > 95% degradation in a 5 day BOD test(2). ANAEROBIC: Methyl acetate is listed as a compound that should undergo ultimate anaerobic biodegradation in industrial wastewater(1). Methyl acetate achieved 96% anaerobic utilization efficiency after a 90 day acclimation period in completely mixed reactors(2). Methyl acetate, present at 50 ppm C, was completely degraded in anaerobic aquifer slurries at a rate of 16.6 ppm C/day and an acclimation period of 0 to 15 days(3). Alcaligenes faecalis, isolated from activated sludge, was found to oxidize methyl acetate after a short lag period(1). Environmental Abiotic Degradation of Methyl acetate The rate constant for the vapor-phase reaction of methyl acetate with photochemically-produced hydroxyl radicals has been estimated as 2.6X10-13 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 41 days at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). A base-catalyzed second-order hydrolysis rate constant of 1.3X10-1 L/mole-sec(SRC) was estimated using a structure estimation method(2); this corresponds to half-lives of 1.7 years and 63 days at pH values of 7 and 8, respectively(2). Methyl acetate does not contain chromophores that absorb at wavelengths >290 nm(3) and, therefore, is not expected to be susceptible to direct photolysis by sunlight(SRC). An estimated BCF of 3.2 was calculated in fish for methyl acetate(SRC), using a log Kow of 0.18(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). The Koc of methyl acetate is estimated as 9.1(SRC), using a log Kow of 0.18(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that methyl acetate is expected to have very high mobility in soil(SRC). The Henry's Law constant for methyl acetate is 1.15X10-4 atm-cu m/mole(1). This Henry's Law constant indicates that methyl acetate is expected to volatilize from water surfaces(2). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 5 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 5 days(SRC). Methyl acetate's Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). The potential for volatilization of methyl acetate from dry soil surfaces may exist(SRC) based upon a vapor pressure of 216.2 mm Hg(3). Methyl acetate was detected, not quantified, in the drinking water from multiple sources in the United States(1). Effluent Concentrations of Methyl acetate Methyl acetate was detected in the waste stream of industrial waste after deep-well injection between 1971 to 1972 at <0.5 mg/L DOC(1). Methyl acetate was detected, not quantified, in the effluent gas from refuse waste obtained from a food center(2). Methyl acetate was detected in active blower exhaust between October and November 1989 at a concentration of 144 ug/cu m from a wastewater treatment sludge/wood chip compost pile located at the Peninsula Composting Facility(3). Methyl acetate was also detected in the biowaste during the aerobic composting process (ACP) at a concentration of 24 mg/cu m(4). Methyl acetate was detected, not quantified, as a volatile organic compound in kitchen waste, kitchen waste exudate, stored food exudate(5), and in garden waste exudate(6). Methyl acetate was also detected in 4 out of 4 biodegradable waste samples collected from household waste at concentrations ranging from 0.1 to 1 mg/cu m and in 5 out of 7 mixed kitchen waste samples at a concentration of <0.1 mg/cu m(7). Methyl acetate was detected as an emission from the production of RDX at the Holston Army Ammunition Plant, TN at an emission rate of 733 lbs/day(8). Atmospheric Concentrations URBAN/SUBURBAN: Methyl acetate was detected as a volatile organic compound collected from UK cities at 0.0018%(1). Methyl acetate was detected in the emissions collected from the Gubrist highway tunnel, Switzerland, in 2004; the emission factor was reported to be 0.03 mg/kg(2). INDOOR: Methyl acetate was detected from the emissions from carpet with a PVC backing in an environmental chamber; the emission rate was 0.08 mg/cu m in a 24 hour time period(1). Methyl acetate was also detected, not quantified, from the emissions from furniture coatings in an environmental chamber(2). Methyl acetate was detected, not quantified, in household consumer products, specifically liquid all purpose adhesive(3). RURAL/REMOTE: Methyl acetate was detected, not quantified, in forest air samples collected from the Eggegbirge in North Rhine-Westfalia, Germany(1). SOURCE DOMINATED: Methyl acetate was detected, not quantified, in the air of the industrialized Kanawha Valley, WV in 1977(1). Methyl acetate was reported in fresh grapefruit juice at a concentration of 0.026 ppm(1). Methyl acetate was detected in the emissions of corn silage, alfalfa silage, cereal silage and almond shells at concentrations of 3.14, 6.15, 0.29 and 0.10 nL/L(2). Methyl acetate was detected, not quantified, as a volatile component in floured chickpea seed(3), chicken meat(4), Cabernet Sauvignon wine from Napa Valley, CA(5). Methyl acetate is reported as found in coffee(6). Methyl acetate was reported in the volatile fraction from Kiwi Fruit flowers (Actinidia chinensis) at 0.57% of the total area(1). Methyl acetate was detected, not quantified in cow milk(1). Methyl acetate was identified as a solvent in a sample of printer's inks at a concentration of 0.1% (W/W)(1). According to the 2012 TSCA Inventory Update Reporting data, the number of persons reasonably likely to be exposed in the industrial manufacturing, processing, and use of methyl acetate is 5000; the data may be greatly underestimated(1). NIOSH (NOES Survey 1981-1983) has statistically estimated that 20,455 workers (6,018 of these were female) were potentially exposed to methyl acetate in the US(1). Occupational exposure to methyl acetate may occur through inhalation and dermal contact with this compound at workplaces where methyl acetate is produced or used. Monitoring data indicate that the general population may be exposed to methyl acetate via inhalation of ambient air, ingestion of food and dermal contact with this compound or other consumer products containing methyl acetate(SRC). A survey was conducted in the second half of a work week on 39 male workers who were occupationally exposed to styrene in combination with methanol and methyl acetate during the production of plastic buttons. Time-weighted average exposure during an 8-h shift to styrene (Sty-A) and methyl acetate was monitored by carbon cloth-equipped personal samplers and to methanol by water-equipped ones. Urine samples were collected near the end of the shift and analyzed for mandelic (MA-U) and phenylglyoxylic acids (PhGA-U) by HPLC. Geometric mean styrene concentration was 12.4 ppm (micrograms/g) with the maximum of 46 ppm, whereas the values for methanol and methyl acetate in combination were 23.5 ppm and 229 ppm, respectively. The relationship of MA-U and PhGA-U with Sty-A was examined by linear regression analysis. The equations for the regression lines were compared with the results from a previous survey (Ikeda et al. 1983) in which workers were exposed only to styrene, and the methods employed were identical with that in the present study. The comparison showed no evidence to suggest that styrene metabolism is suppressed by coexposure to methanol and methyl acetate at low concentrations below the current occupational exposure limit of 200 ppm. What is Methyl Acetate? Methyl acetate (also known as methyl ethanoate, acetic acid methyl ester, MeOAc, Tereton, Devoton) is a carboxylate ester with a molecular formula of C3H6O2. It is a clear, colourless liquid that has a typical ester odour similar to glues and nail polish removers. It is very flammable with a flashpoint of -10° C and a flammability rating of 3. Methyl acetate is commonly used in low toxicity solvents such as glues, nail polish removers. It is highly miscible with all common organic solvents (alcohols, ketones, glycols, esters) but has only slight miscibility in water, but becomes more soluble in water with elevated temperatures. It is commonly found in fruits such as apples, grapes and bananas. Methyl acetate is a carboxylate ester as it contains a carbonyl group bonded to an OR group and is produced through the esterification of acetic acid with methanol. How is methyl acetate produced? There are various methods of producing methyl acetate. One that is used industrially is via carbonylation. These types of reactions bring together carbon monoxide substrates. To produce methyl acetate, methanol is heated alongside acetic acid in the presence of sulfuric acid. Another method of production is the esterification of methanol and acetic acid in the presence of a strong acid. Sulfuric acid is a common catalyst also used in this reaction. Handling, Storage & Distribution Hazards & Toxicity Methly acetate has a NFPA health rating of 2 and can cause temporary incapacitation or residual injury. If inhaled or ingested, headaches, dizziness, drowsiness and fatigue can occur. Contact with the eyes can cause irritation. It has a flammability rating of 3 and can be ignited under most ambient temperature conditions residing from its low flash point of -10 °C. When ablaze, methyl acetate emits heavy, irritating, and toxic fumes that can travel considerable distances. These vapours are also explosive and risk bursting if able to return to the source of ignition. Methyl acetate’s reactivity is aligned with other compounds of the ester group. In th
Methyl Acetoacetate
MSA; Methanesulfonic Acid; Sulphomethane; Acide methanesulfonique; Acide methanesulfonique, Kyselina methansulfonova; Methylsulphonic acid; ácido metanosulfónico; Methansulfonsäure CAS NO: 75-75-2
Methyl Acrylate
Methyl Acrylate; Acrylic acid, methyl ester; 2-Propenoic acid, methyl ester; Methoxycarbonylethylene; Methyl acrylate, monomer; Methyl propenate; Methyl propenoate; Methyl-2-propenoate; Propenoic acid, methyl ester; Acrylate de methyle (French); Acrylsaeuremethylester (German); Methyl-acrylat (German); Methylacrylaat (Dutch); Metilacrilato (Italian); cas no: 96-33-3
METHYL AMYL KETONE
Methyl amyl ketone is a colorless liquid with a strong, sweet odor.
Methyl amyl ketone is a member of the ketone family of organic compounds and has a molecular formula of C6H12O.
Methyl amyl ketone is commonly used as a solvent in various industrial applications due to Methyl amyl ketone unique properties and advantages.

CAS Number: 110-43-0
EC Number: 203-767-1
Molecular Dormula: C7H14O
Molar Weight: 114.185

Synonyms: 2-HEPTANONE, Heptan-2-one, 110-43-0, Methyl pentyl ketone, Butylacetone, Amyl methyl ketone, Methyl amyl ketone, Methyl n-amyl ketone, n-Amyl methyl ketone, n-Pentyl methyl ketone, Heptanone, Pentyl methyl ketone, Methyl n-pentyl ketone, Ketone, methyl pentyl, Amyl-methyl-cetone, Methyl-amyl-cetone, Ketone C-7, FEMA No. 2544, NSC 7313, CHEMBL18893, CHEBI:5672, DTXSID5021916, 89VVP1B008, NSC-7313, Methyl-n-amylketone, DTXCID601916, 2-Heptanone (natural), FEMA Number 2544, Amyl-methyl-cetone [French], Methyl-amyl-cetone [French], CAS-110-43-0, HSDB 1122, EINECS 203-767-1, UN1110 BRN 1699063, UNII-89VVP1B008, AI3-01230, CCRIS 8809, 1-Methylhexanal, 2-Ketoheptane, heptanone-2, methylpentylketone, 2-heptanal, 2-Oxoheptane, Nat. 2-Heptanone, 2-Heptanone, 98%, 2-Heptanone, 99%, 2-HEPTANONE [MI], EC 203-767-1, n-C5H11COCH3, 2-HEPTANONE [FCC], 2-HEPTANONE [FHFI], 2-HEPTANONE [HSDB], SCHEMBL29364, 4-01-00-03318 (Beilstein Handbook Reference), 2-heptanone_GurudeebanSatyavani, SCHEMBL1122991, WLN: 5V1, 2, Heptanone, analytical standard, 2-Heptanone(Methyl Amyl Ketone), NSC7313, 2-Heptanone, natural, 98%, FG, Methyl n-Amyl Ketone Reagent Grade, ZINC1531087, Tox21_20216, Tox21_302935, BBL011381, BDBM50028842, LMFA12000004, MFCD00009513, STL146482, 2-Heptanone, >=98%, FCC, FG, Methyl Amyl Ketone (Fragrance Grade), AKOS000120708, UN 1110, NCGC00249180-01, NCGC00256611-01, NCGC00259713-01, VS-02935, FT-0612484, H0037, EN300-21047, C08380, A802193, Q517266, J-509557, n-Amyl methyl ketone [UN1110] [Flammable liquid], Ick, MAK, hICK, LCK2, fj04c02, KIAA0936, kinase ICK, 2-Heptanal, 2-Heptanon, 2-Heptanone, heptan-2-one, 2-Oxoheptane, 2-Ketoheptane, 1-Methylhexanal, Methyl amyl ketone, Amyl-methyl-cetone, n-Amyl methyl ketone, Methyl n-pentyl ketone, Intestinal cell kinase, Laryngeal cancer kinase 2, amyl-methyl-cetone(french)

Methyl amyl ketone, also known as Methyl amyl ketone, or Heptan-2-one, is a ketone with the molecular formula C7H14O.
Methyl amyl ketone is a colorless, water-like liquid with a banana-like, fruity odor.
Methyl amyl ketone has a neutral formal charge, and is only slightly soluble in water.

Methyl amyl ketone is a natural product found in Aloe africana, Zingiber mioga, and other organisms with data available.
Methyl amyl ketone is a metabolite found in or produced by Saccharomyces cerevisiae.

Methyl amyl ketone is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.
Methyl amyl ketone is used by consumers, by professional workers (widespread uses), in formulation or re-packing and at industrial sites.

Methyl amyl ketone is listed by the FDA as a "food additive permitted for direct addition to food for human consumption" (21 CFR 172.515), and Methyl amyl ketone occurs naturally in certain foods (e.g., beer, white bread, butter, various cheeses and potato chips).

The mechanism of action of Methyl amyl ketone as a pheromone at odorant receptors in rodents has been investigated.
Methyl amyl ketone is present in the urine of stressed rats and believe that Methyl amyl ketone is used as a means to alert other rats.

Certain species of worms are attracted to Methyl amyl ketone and bacteria can use this as a means of pathogenesis.
Methyl amyl ketone has also been found to be excreted by honey bees when they bite small pests within the colony such as wax moth larvae and Varroa mites.

Though Methyl amyl ketone was historically believed to be an alarm pheromone, Methyl amyl ketone has been shown to act as an anaesthetic on the pests, enabling the honey bee to stun the pest and eject Methyl amyl ketone from the hive.
The work could lead to the use of Methyl amyl ketone as an alternative local anaesthetic to lidocaine, which although well established for clinical use, has the disadvantage of provoking allergic reactions in some people.

Methyl amyl ketone was one of the metabolites of n-heptane found in the urine of employees exposed to heptane in shoe and tire factories.
This commonly occurs from exposure to plasticisers.

Methyl amyl ketone can be absorbed through the skin, inhaled and consumed.
Exposure to Methyl amyl ketone can cause irritation of skin/eyes, respiratory system, headaches, vomiting, and nausea.

In mice 2-H is a urinary component and pheromone.
Methyl amyl ketone has a high affinity for the main olfactory epithelium.
Gaillard et al 2002 found that Methyl amyl ketone agonizes one specific olfactory receptor, and that that OR only binds 2-H.

Methyl amyl ketone is a colorless liquid with a strong, sweet odor.
Methyl amyl ketone is a member of the ketone family of organic compounds and has a molecular formula of C6H12O.
Methyl amyl ketone is commonly used as a solvent in various industrial applications due to Methyl amyl ketone unique properties and advantages.

One of the key advantages of Methyl amyl ketone is its high solvency power.
Methyl amyl ketone is a very effective solvent for many organic compounds, particularly those that are insoluble in water.

This makes Methyl amyl ketone useful in applications such as paint and coating formulations, adhesives, and inks.
Methyl amyl ketone is also used as a solvent in the production of various chemicals, such as pharmaceuticals and pesticides.

Another advantage of Methyl amyl ketone is Methyl amyl ketone relatively low toxicity compared to other ketones.
Methyl amyl ketone has a lower vapor pressure and boiling point than other ketones, which means that Methyl amyl ketone is less likely to vaporize and become a hazard in the workplace.

However, Methyl amyl ketone is still important to handle Methyl amyl ketone with care and use Methyl amyl ketone in accordance with appropriate safety protocols.
This includes the use of protective equipment, such as gloves and safety goggles, as well as proper ventilation and storage.

Methyl amyl ketone is also used in the production of fragrances and flavors, as well as in the production of resins and polymers.
Methyl amyl ketone is a useful intermediate in the production of other chemicals and is used as a starting material in the production of other ketones.
Methyl amyl ketone is also used as a fuel additive to improve the combustion efficiency of gasoline.

Methyl amyl ketone has a high solvent activity, slow evaporation rate, low density, low surface tension, and high boiling point.
These properties make Methyl amyl ketone a very good solvent for cellulosic lacquers, acrylic lacquers, and high-solids coatings.
Because regulations limit the weight of solvent per gallon of coating, formulators favor the use of low-density solvents that help reduce the VOC content of a coating.

Methyl amyl ketone is lower in density than ester, aromatic hydrocarbons, and glycol ether solvents with similar evaporation rates.
The low density and high activity of Methyl amyl ketone are significant advantages when formulating high-solids coatings to meet VOC guidelines.
Methyl amyl ketone is also used as a polymerization solvent for high solids acrylic resins.

The chemical substances for Methyl amyl ketone are listed as Inert Ingredients Permitted for Use in Nonfood Use Pesticide Products, and in Food Use Pesticide Products with limitations, under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA).

Applications of Methyl amyl ketone:
Auto OEM
Auto refinish
General industrial coatings
Herbicides int
Paints & coatings
Process solvents

Uses of Methyl amyl ketone:
Methyl amyl ketone is used for the synthesis of industrial solvents and fragrances, such as the components used to make caryophyllum oil.

Micro-amounts are suitable for carnation or other octyl fragrance types, which can be shared with Artemisia or basil, seashell oil in herb fragrance types, the formation of a new head fragrance.
With the spice, fruit flavor can coordinate and good synthesis.

In the food flavor, for the banana type food flavor can increase the milk fat flavor, also suitable for coconut, cream, cheese flavor food flavor.
GB 2760-96 provides for the permitted use of flavorants.

Methyl amyl ketone is mainly used in the preparation of cheese, banana, cream and coconut flavor.
Methyl amyl ketone is used for the synthesis of industrial solvents and fragrances, such as the components used to make caryophyllum oil.

Methyl amyl ketone is widely used in industrial solvent, fiber, medicine, pesticide, perfume chemical industry and other fields
Methyl amyl ketone is used in organic synthesis; Trace suitable for carnation or other octanoaromatic type, in the herb fragrance can be shared with the grass Artemisia or basil, Sea oil, the formation of new head fragrance.

With the spice, fruit flavor can coordinate and good synthesis.
In the food flavor, for the banana type food flavor can increase the milk fat flavor, also suitable for coconut, cream, cheese flavor food flavor; For industrial solvents, fiber, medicine, pesticide, perfume and Chemical Industry.

Methyl amyl ketone is used as a solvent for resins and lacquers, a fragrance for cosmetics, and a flavor for foods.
Methyl amyl ketone is solvent for nitrocellulose lacquers.

Methyl amyl ketone is used in perfumery as constituent of artificial carnation oils; as industrial solvent
Methyl amyl ketone is used as a solvent in metal roll coatings and in synthetic resin finishes and lacquers, as a flavoring agent, and in perfumes.

Methyl amyl ketone can be used in the following industries:
Food & Feed, Pharma & Life Science, Other Industries, Cosmetics & Personal Care

Methyl amyl ketone can be applied as:
Oleochemicals, Fragrances, Food Additives

Consumer Uses:
Methyl amyl ketone is used in the following products: plant protection products, adhesives and sealants, coating products, fillers, putties, plasters, modelling clay, cosmetics and personal care products, air care products, biocides (e.g. disinfectants, pest control products), perfumes and fragrances, polishes and waxes and washing & cleaning products.
Other release to the environment of Methyl amyl ketone is likely to occur from: indoor use as processing aid and outdoor use as processing aid.

Other Consumer Uses:
Binder
Paint additives and coating additives not described by other categories
Solvent
Solvents (which become part of product formulation or mixture)

Widespread uses by professional workers:
Methyl amyl ketone is used in the following products: washing & cleaning products, fertilisers, plant protection products, coating products, cosmetics and personal care products, polishes and waxes, laboratory chemicals and polymers.
Methyl amyl ketone is used in the following areas: agriculture, forestry and fishing.

Methyl amyl ketone is used for the manufacture of: machinery and vehicles.
Other release to the environment of Methyl amyl ketone is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Uses at industrial sites:
Methyl amyl ketone is used in the following products: coating products, photo-chemicals, laboratory chemicals and semiconductors.
Methyl amyl ketone is used in the following areas: scientific research and development.

Methyl amyl ketone is used for the manufacture of: machinery and vehicles, chemicals and electrical, electronic and optical equipment.
Release to the environment of Methyl amyl ketone can occur from industrial use: in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.

Industry Uses:
Cleaning agent
Intermediates
Paint additives and coating additives not described by other categories
Solvent
Solvents (which become part of product formulation or mixture)

Industrial Processes with risk of exposure:
Painting (Solvents)
Plastic Composites Manufacturing

Key attributes of Methyl amyl ketone:
Excellent solvent activity
High dilution ratio
Inert - Food use with limitations
Inert - Nonfood use
Low density
Low surface tension
Non-HAP
Non-SARA
REACH compliant
Readily Biodegradable
Slow evaporation rate
Urethane grade

Nature of Methyl amyl ketone:
Methyl amyl ketone is colorless, fragrant, stable liquid.
Methyl amyl ketone is slightly soluble in water.

Methyl amyl ketone is melting Point -35 °c.
Methyl amyl ketone is boiling point 151.5 °c.

Methyl amyl ketone is relative density 0.8166.
Methyl amyl ketone is refractive index 4067.

Methyl amyl ketone is viscosity (25 °c) 0.766MPA.
Methyl amyl ketone is flash point 47.
Methyl amyl ketone is very slightly soluble in water, soluble in ethanol, ether.

Preparation Method of Methyl amyl ketone:
The extraction method is obtained by extracting clove oil or cinnamon oil.
2-heptanol method is prepared by dehydrogenation of 2-heptanol.
n-butyl acetoacetate method.

Production Method of Methyl amyl ketone:
1. Obtained by saponification of ethyl butyl acetoacetate.
Ethyl butyl acetoacetate was added to 5% sodium hydroxide solution and stirred at room temperature for 4H.

The layers were allowed to stand and separated.
The aqueous layer reacts with 50% sulfuric acid, and as the reaction becomes moderate to the release of carbon dioxide, the reaction is slowly heated to boil, distilling from 0.33 to 0.5% of the original total volume.

The distillate was made alkaline with solid sodium hydroxide and then distilled off 80-90%.
The distillate is layered, the ketone is separated into layers, and the water layer is distilled out for one third.

After the ketone is removed from the distilled material, the water layer is further distilled out for one third, which is repeated in this way, the resulting Methyl amyl ketone was collected as far as possible.
The resulting Methyl amyl ketone was combined and washed with calcium chloride solution.
After drying, Methyl amyl ketone was obtained by distillation with a yield of 50-60%.

2. The extraction method is obtained by extracting clove oil or cinnamon oil.

3. 2-heptanol method from 2-heptanol dehydrogenation.
At room temperature with sodium hydroxide saponification of butyl acetyl ethyl acetate, then add sulfuric acid, heating distillation, distillate with sodium hydroxide neutralization, distillation, plus calcium chloride concentrated solution to remove residual ethanol, after drying and distillation.

Manufacturing Methods of Methyl amyl ketone:
Produced industrially by reductive condensation of acetone with butyraldehyde in one or two steps.

General Manufacturing Information of Methyl amyl ketone:

Industry Processing Sectors:
All Other Basic Organic Chemical Manufacturing
Computer and Electronic Product Manufacturing
Construction
Furniture and Related Product Manufacturing
Miscellaneous Manufacturing
Non-metallic Mineral Product Manufacturing (includes clay, glass, cement, concrete, lime, gypsum, and other non-metallic mineral product manufacturing)
Not Known or Reasonably Ascertainable
Paint and Coating Manufacturing
Transportation Equipment Manufacturing

Handling and Storage of Methyl amyl ketone:

Nonfire Spill Response:
ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.
All equipment used when handling Methyl amyl ketone must be grounded.

Do not touch or walk through spilled material.
Stop leak if you can do Methyl amyl ketone without risk.

Prevent entry into waterways, sewers, basements or confined areas.
A vapor-suppressing foam may be used to reduce vapors.

Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers.
Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL:
Dike far ahead of liquid spill for later disposal.
Water spray may reduce vapor, but may not prevent ignition in closed spaces.

Storage of Methyl amyl ketone:
Keep in tightly closed container in a cool and dry place, protected from light.
When stored for more than 24 months, quality should be checked before use.
We believe the above information to be correct but we do not present Methyl amyl ketone as all inclusive and as such should be used as a guide.

Chemical Reactivity of Methyl amyl ketone:

Reactivity Profile:
Methyl amyl ketone reacts exothermically with many acids and bases to produce flammable gases (e.g., H2).
The heat may be sufficient to start a fire in the unreacted portion.

Reacts with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas and heat.
Incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides.

Incompatible with many oxidizing agents including nitric acid, nitric acid/hydrogen peroxide mixture, and perchloric acid.
May form peroxides.

Reactivity with Water:
No reaction

Reactivity with Common Materials:
Will attack some forms of plastic.

Stability During Transport:
Stable

Neutralizing Agents for Acids and Caustics:
Not pertinent

Polymerization:
Not pertinent

Inhibitor of Polymerization:
Not pertinent

First Aid Measures of Methyl amyl ketone:

Eye:
IRRIGATE IMMEDIATELY - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids.
Get medical attention immediately.

Skin:
SOAP WASH - If this chemical contacts the skin, wash the contaminated skin with soap and water.

Breathing:
FRESH AIR - If a person breathes large amounts of this chemical, move the exposed person to fresh air at once.
Other measures are usually unnecessary.

Swallow:
MEDICAL ATTENTION IMMEDIATELY - If this chemical has been swallowed, get medical attention immediately.

Fire Fighting of Methyl amyl ketone:
The majority of these products have a very low flash point.
Use of water spray when fighting fire may be inefficient.

For fire involving UN1170, UN1987 or UN3475, alcohol-resistant foam should be used.
Ethanol (UN1170) can burn with an invisible flame.
Use an alternate method of detection (thermal camera, broom handle, etc.).

SMALL FIRE:
Dry chemical, CO2, water spray or alcohol-resistant foam.

LARGE FIRE:
Water spray, fog or alcohol-resistant foam.
Avoid aiming straight or solid streams directly onto Methyl amyl ketone.
If it can be done safely, move undamaged containers away from the area around the fire.

FIRE INVOLVING TANKS OR CAR/TRAILER LOADS:
Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.
Cool containers with flooding quantities of water until well after fire is out.

Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
ALWAYS stay away from tanks engulfed in fire.

For massive fire, use unmanned master stream devices or monitor nozzles.
If this is impossible, withdraw from area and let fire burn.

Fire Hazards of Methyl amyl ketone:

Flash Point:
117°F O.C. 102°F C.C.

Flammable Limits in Air: 1.11%-7.9%

Fire Extinguishing Agents:
Dry chemical, alcohol foam, carbon dioxide

Fire Extinguishing Agents Not to Be Used:
Water may be ineffective.

Special Hazards of Combustion Products:
Currently not available

Behavior in Fire:
Currently not available

Auto Ignition Temperature:
740°F

Spillage Disposal of Methyl amyl ketone:

Personal protection:
Filter respirator for organic gases and vapours adapted to the airborne concentration of Methyl amyl ketone.
Collect leaking and spilled liquid in sealable metal containers as far as possible.

Absorb remaining liquid in dry sand or inert absorbent.
Then store and dispose of according to local regulations. Do NOT wash away into sewer.

Identifiers of Methyl amyl ketone:
CAS Number: 110-43-0
ChEBI: CHEBI:5672
ChEMBL: ChEMBL18893
ChemSpider: 7760
ECHA InfoCard: 100.003.426
KEGG: C08380
PubChem CID: 8051
UNII: 89VVP1B008
CompTox Dashboard (EPA): DTXSID5021916
InChI: InChI=1S/C7H14O/c1-3-4-5-6-7(2)8/h3-6H2,1-2H3
Key: CATSNJVOTSVZJV-UHFFFAOYSA-N
InChI=1/C7H14O/c1-3-4-5-6-7(2)8/h3-6H2,1-2H3
Key: CATSNJVOTSVZJV-UHFFFAOYAO
SMILES: O=C(C)CCCCC

Substance: Methyl amyl ketone
CAS: 110-43-0
EC number: 203-767-1
REACH compliant: Yes
Min. purity / concentration: 100%
Appearance: Liquid
Grades: Cosmetic, Pharma, Technical

IUPAC name: Methyl amyl ketone
Molecular formula: C7H14O
Molar Weight [g/mol]: 114.185

EC / List no.: 203-767-1
CAS no.: 110-43-0
Mol. formula: C7H14O

Synonyms: Methyl pentyl ketone, Methyl amyl ketone
Linear Formula: CH3(CH2)4COCH3
CAS Number: 110-43-0
Molecular Weight: 114.19
EC Number: 203-767-1

Properties of Methyl amyl ketone:
Chemical formula: C7H14O
Molar mass: 114.18 g/mol
Appearance: Clear liquid
Odor: banana-like, fruity
Density: 0.8 g/mL
Melting point: −35.5 °C (−31.9 °F; 237.7 K)
Boiling point: 151 °C (304 °F; 424 K)
Solubility in water: 0.4% by wt
Vapor pressure: 3 mmHg (20°C)
Magnetic susceptibility (χ): -80.50·10−6 cm3/mol

Appearance: colorless clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: Yes
Specific Gravity: 0.81400 to 0.81900 @ 25.00 °C.
Pounds per Gallon - (est).: 6.773 to 6.815
Refractive Index: 1.40800 to 1.41500 @ 20.00 °C.
Melting Point: -26.90 °C. @ 760.00 mm Hg
Boiling Point: 149.00 to 150.00 °C. @ 760.00 mm Hg
Boiling Point: 151.00 °C. @ 2.60 mm Hg
Acid Value: 2.00 max. KOH/g
Vapor Pressure: 4.732000 mmHg @ 25.00 °C. (est)
Flash Point: 117.00 °F. TCC ( 47.22 °C. )
logP (o/w): 1.980

Formula: C7H14O / CH3(CH2)4COCH3
Molecular mass: 114.18
Boiling point: 151°C
Melting point: -35.5°C
Relative density (water = 1): 0.8
Solubility in water: poor
Vapour pressure, kPa at 25°C: 0.2
Relative vapour density (air = 1): 3.9
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01
Flash point: 39°C
Auto-ignition temperature: 393°C
Explosive limits, vol% in air: 1-5.5

Molecular Weight: 114.19
XLogP3: 2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 4
Exact Mass: 114.104465066
Monoisotopic Mass: 114.104465066
Topological Polar Surface Area: 17.1 Ų
Heavy Atom Count: 8
Complexity: 66.8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Related Products of Methyl amyl ketone:
Nivalenol
(R)-Ochratoxin α
Di-N-heptytin Dichloride-D30
Ergosinine
3-Ethyl-2-methylpentane

Alternate Chemical Names:
BUTYLACETONE
2-HEPTANONE
2-KETOHEPTANE
METHYL (N-AMYL) KETONE
METHYL AMYL KETONE
METHYL N-AMYL KETONE
METHYL N-PENTYL KETONE
METHYL PENTYL KETONE
METHYLAMYL KETONE
1-METHYLHEXANAL
N-AMYL METHYL KETONE
N-PENTYL METHYL KETONE
2-OXOHEPTANE
PENTYL METHYL KETONE

Names of Methyl amyl ketone:

Regulatory process names:
2-Heptanone
2-Heptanone (natural)
Amyl methyl ketone
Amyl-methyl-cetone
Butylacetone
Heptan-2-one
Heptan-2-one
heptan-2-one
heptan-2-one; methyl amyl ketone
Ketone C-7
Ketone, methyl pentyl
Methyl amyl ketone
methyl amyl ketone
Methyl n-amyl ketone
Methyl n-pentyl ketone
Methyl pentyl ketone
Methyl-amyl-cetone
n-AMYL METHYL KETONE
n-Amyl methyl ketone
n-Pentyl methyl ketone
Pentyl methyl ketone

Translated names:
2-heptanon (no)
2-heptanon (sv)
2-heptanonas (lt)
2-heptanoni (fi)
eptan-2-one (it)
heptaan-2-on (nl)
Heptaan-2-oon (et)
heptan-2-on (cs)
heptan-2-on (da)
Heptan-2-on (de)
heptan-2-on (hr)
heptan-2-on (no)
heptan-2-on (pl)
heptan-2-on (sl)
heptan-2-on (sv)
heptan-2-ona (es)
heptan-2-ona (ro)
heptan-2-one; méthylamylcétone (fr)
heptan-2-oni (fi)
heptano-2-ona (pt)
heptanons-2 (lv)
heptán-2-on (hu)
heptán-2-ón (sk)
keton metylowo-n-amylowy (pl)
keton metylowo-pentylowy (pl)
methyl(pentyl)keton (cs)
methylpentylketon (da)
Methylpentylketon (de)
metil amil chetone (it)
metil amil keton (sl)
metil amil ketona (ro)
metil-amil-keton (hr)
metil-amil-keton (hu)
metilamilketonas (lt)
metilamilketons (lv)
metyl(pentyl)ketón (sk)
metyloamyloketon (pl)
metylpentylketon (no)
metylpentylketon (sv)
metyyliamyyliketoni (fi)
Metüülamüülketoon (et)
méthyl-n-amylcétone (fr)
επταν-2-όν (el)
метил амил кетон (bg)
хептан-2-oн (bg)

CAS name:
2-Heptanone

IUPAC names:
2-HEPTANONE
2-Heptanone
2-heptanone
2-Heptanoneheptane-2-onheptane-2-oneheptane-2-one methyl amyl ketoneMETHYL AMYL KETONEMethyl N Amyl KetoneMETHYL N-AMYL KETONEMethyl N.A Ketone (2-heptanone)
heptan-2-on
Heptan-2-one
heptan-2-one
Heptan-2-one
heptan-2-one
heptan-2-one methyl amyl ketone
METHYL AMYL KETONE
Methyl Amyl Ketone
Methyl amyl ketone
methyl amyl ketone
Methyl N Amyl Ketone
METHYL N-AMYL KETONE
Methyl N.A Ketone (2-Heptanone)

Preferred IUPAC name:
Heptan-2-one

Trade names:
EH2350PTA-1128(M)
EH2350PTA-2260(M)
EH2350PTA-RAL9002(M)
MAK

Other names:
Amyl methyl ketone
Butyl acetone
Methyl n-amyl ketone
Methyl pentyl ketone

Other identifiers:
110-43-0
606-024-00-3
Methyl Benzoate
MSA; Methanesulfonic Acid; Sulphomethane; Acide methanesulfonique; Acide methanesulfonique, Kyselina methansulfonova; Methylsulphonic acid; ácido metanosulfónico; Methansulfonsäure CAS NO: 75-75-2
MÉTHYL BENZOPHÉNONE
METHYLCELLULOSE, N° CAS : 9004-67-5 - Méthylcellulose, Nom INCI : METHYLCELLULOSE, Additif alimentaire : E461, Ses fonctions (INCI) : Agent fixant : Permet la cohésion de différents ingrédients cosmétiques, Stabilisateur d'émulsion : Favorise le processus d'émulsification et améliore la stabilité et la durée de conservation de l'émulsion. Agent stabilisant : Améliore les ingrédients ou la stabilité de la formulation et la durée de conservation. Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques. Noms français : Méthyl cellulose Noms anglais : CELLULOSE METHYLATE; CELLULOSE, METHYL ETHER; Methyl cellulose ether; METHYLCELLULOSE. Utilisation et sources d'émission :Additif alimentaire, agent épaississant
Methyl cellulose
SYNONYMS Tyloses; Methyl Ether Cellulose; Viscol; Cellogran; Cellothyl; Cellulose methylate; Ccellumeth; Cethylose; Cethytin; Methylcel MC; CAS NO. 9004-67-5
METHYL CELLULOSE
Methyl cellulose is the sodium salt of carboxymethyl cellulose, an anionic cellulose ether in which some of the hydroxyl groups of the cellulose molecule have been replaced with a carboxy group.
Methyl cellulose is a thickening agent that is made by reacting cellulose (wood pulp, cotton lint) with a derivative of acetic acid (the acid in vinegar).
Methyl cellulose is a water dispersible sodium salt of carboxy-methyl ether of cellulose that forms a clear colloidal solution.

CAS Number: 9004-32-4
EC Number: 618-378-6
Molecular Formula: [C6H7O2(OH)x(OCH2COONa)]
Molecular Weight: 262.19 g/mol

Synonyms: cellulose gum, CMC, Na CMC, Sodium cellulose glycolate, Sodium CMC, Cellulose Glycolic Acid Sodium Salt, Sodium Carboxymethyl Cellulose, Sodium Cellulose Glycolate, Sodium Tylose, Tylose Sodium, C.M.C., C.m.c., C.m.c. (TN): , Carboxymethylcellulose sodium, Carboxymethylcellulose sodium (usp), Carmellose sodium: , Carmellose sodium (JP15, Celluvisc, Celluvisc (TN): , Sodium 2,3,4,5,6-pentahydroxyhexanal acetic acid, 9004-32-4, SODIUM CARBOXYMETHYL CELLULOSE, Cellulose gum, Carboxymethyl cellulose, sodium salt, sodium;2,3,4,5,6-pentahydroxyhexanal;acetate, Carboxymethylcellulose sodium (USP), Carboxymethylcellulose cellulose carboxymethyl ether, CMC powder, Celluvisc (TN), C8H15NaO8, Carmellose sodium (JP17), CHEMBL242021, C.M.C. (TN), CHEBI:31357, E466, K625, D01544, Carboxymethyl cellulose sodium - Viscosity 100 - 300 mPa.s, Cellulose Glycolic Acid Sodium Salt (n=approx. 500), Sodium Carboxymethyl Cellulose (n=approx. 500)Sodium Cellulose Glycolate (n=approx. 500), Sodium Tylose (n=approx. 500), Tylose Sodium (n=approx. 500), 12M31Xp, 1400Lc, 2000Mh, 30000A, 7H3Sf, 7H3Sx, 7H4Xf, 7L2C, 7Mxf, 9H4F-Cmc, 9H4Xf, 9M31X, 9M31Xf, AG, Ac-Of-Sol, Antizol, Aoih, Aquacel, Aquaplast, Blanose, CMC, CMC-Na, Cellcosan, Cellofas, Cellogen, Cellpro, Cellugel, Cepol, Cmc-Clt, Cmc-Lvt, Cmcna, Collowel, Covagel, Dehydazol, Diko, Dissolvo, Dte-Nv, Ethoxose, F-Sl, Finnfix, Hpc-Mfp, KMTs, Kiccolate, Lovosa, Lucel, Marpolose, Micell, Natrium-Carboxymethyl-Cellulose, Nymcel, Orabase, PATs-V, Pac-R, Relatin, Scmc, Serogel, Sichozell, Sunrose, T.P.T, VinoStab, Yo-Eh, Yo-L, Yo-M, Substituents:: , Hexose monosaccharide, Medium-chain aldehyde, Beta-hydroxy aldehyde, Acetate salt, Alpha-hydroxyaldehyde, Carboxylic acid salt, Secondary alcohol, Carboxylic acid derivative, Carboxylic acid, Organic alkali metal salt, Monocarboxylic acid or derivatives, Polyol, Organic sodium salt, Aldehyde, Hydrocarbon derivative, Alcohol, Organic oxide, Carbonyl group, Primary alcohol, Organic salt, Organic zwitterion, Aliphatic acyclic compound, Carboxymethyl cellulose, Cellulose, carboxymethyl ether, 7H3SF, AC-Di-sol. NF, AKU-W 515, Aquaplast, Avicel RC/CL, B 10, B 10 (Polysaccharide), Blanose BS 190, Blanose BWM, CM-Cellulose sodium salt, CMC, CMC 2, CMC 3M5T, CMC 41A, CMC 4H1, CMC 4M6, CMC 7H, CMC 7H3SF, CMC 7L1, NCMC 7M, CMC 7MT, CMC sodium salt, Carbose 1M, Carboxymethylcellulose sodium salt, Carboxymethylcellulose sodium, low-substituted, Carmellose sodium, low-substituted, Carmethose, Cellofas, Cellofas B, Cellofas B5, Cellofas B50, Cellofas B6, Cellofas C, Cellogel C, Cellogen 3H, Cellogen PR, Cellogen WS-C, Cellpro, Cellufix FF 100, Cellufresh, Cellugel, Cellulose carboxymethyl ether sodium salt, Cellulose glycolic acid, sodium salt, Cellulose gum, Cellulose sodium glycolate, Cellulose, carboxymethyl ether, sodium salt, low-substituted, Celluvisc, Collowel, Copagel PB 25, Courlose A 590, Courlose A 610, Courlose A 650, Courlose F 1000G, Courlose F 20, Courlose F 370, Courlose F 4, Courlose F 8, Daicel 1150, Daicel 1180, Edifas B, Ethoxose, Fine Gum HES, Glikocel TA, KMTs 212, KMTs 300, KMTs 500, KMTs 600, Lovosa, Lovosa 20alk., Lovosa TN, Lucel (polysaccharide), Majol PLX, Modocoll 1200, NaCm-cellulose salt, Nymcel S, Nymcel ZSB 10, Nymcel ZSB 16, Nymcel slc-T, Polyfibron 120, Refresh Plus, Cellufresh Formula, S 75M, Sanlose SN 20A, Sarcell TEL, Sodium CM-cellulose, Sodium CMC, Sodium carboxmethylcellulose, Sodium carboxymethyl cellulose, Sodium carboxymethylcellulose, Sodium cellulose glycolate, Sodium glycolate cellulose, Sodium salt of carboxymethylcellulose, Tylose 666; Tylose C, Tylose C 1000P, Tylose C 30, Tylose C 300, Tylose C 600, Tylose CB 200, Tylose CB series, Tylose CBR 400, Tylose CBR seriesÜ Tylose CBS 30, Tylose CBS 70, Tylose CR, Tylose CR 50, Tylose DKL, Unisol RH, Carboxymethyl cellulose, sodium salt, Cellulose, carboxymethyl ether, sodium salt, Orabase, Cellulose carboxymethyl ether, sodium salt, Cethylose, Cel-O-Brandt, Glykocellon, Carbose D, Xylo-Mucine, Tylose MGA, Cellolax, Polycell, SODIUM CARBOXYMETHYL CELLULOSE, 9004-32-4, sodium;2,3,4,5,6-pentahydroxyhexanal;acetate, UNII-NTZ4DNW8J6, UNII-6QM647NAYU, UNII-WR51BRI81M, UNII-7F32ERV10S, Carboxymethylcelulose, sodium salt, Carboxymethylcellulose sodium (USP), Carboxymethylcellulose sodium [USP], Sodium carboxymethyl cellulose; (Dowex 11), CMC powder, Celluvisc (TN), Carmellose sodium (JP17), CHEMBL242021, C.M.C. (TN), CHEBI:31357, E466, Sodium carboxymethyl cellulose (MW 250000), D01544, Acétate de sodium - hexose (1:1:1) [French] [ACD/IUPAC Name], Natriumacetat -hexose (1:1:1) [German] [ACD/IUPAC Name], Sodium acetate - hexose (1:1:1) [ACD/IUPAC Name], [9004-32-4] [RN], 9004-32-4 [RN], C.M.C. [Trade name], CARBOXYMETHYL CELLULOSE, SODIUM SALT, Carboxymethylcellulose sodium [USP], Carmellose sodium [JP15], Celluvisc [Trade name], cmc, MFCD00081472

Methyl cellulose is a cellulose derivative with carboxymethyl groups (-CH2-COOH) bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone.
Methyl cellulose is often used as its sodium salt, Methyl cellulose.
Methyl cellulose used to be marketed under the name Tylose, a registered trademark of SE Tylose.

Methyl cellulose is an anionic water-soluble polymer derived from cellulose by etherification, substituting the hydroxyl groups with carboxymethyl groups on the cellulose chain.

Methyl cellulose is a water dispersible sodium salt of carboxy-methyl ether of cellulose that forms a clear colloidal solution.
Methyl cellulose is a hygroscopic material that has the ability to absorb more than 50% of water at high humidity.
Methyl cellulose is also a natural polymeric derivative that can be used in detergents, food and textile industries.

Methyl cellulose, the most widely used water-based biopolymer binder in the laboratory at present, is a linear derivative of cellulose substituted by β–linked glucopyranose residues and carboxymethyl groups.

Methyl cellulose is the sodium salt of carboxymethyl cellulose, an anionic cellulose ether in which some of the hydroxyl groups of the cellulose molecule have been replaced with a carboxy group.
Methyl cellulose, also referred to as E 466, is an efficient thickener and binder for water based applications including adhesives, coatings, inks, gel packs, drilling mud and battery electrodes.

Methyl cellulose is the sodium salt of cellulose arboxymethyl and frequently used as viscous agent, paste and barrier agent.

Methyl cellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups.
Methyl cellulose is added in food products as a viscosity modifier or thickener and emulsifier.
Methyl cellulose is also one of the most common viscous polymers used in artificial tears, and has shown to be effective in the treatment of aqueous tear-deficient dry eye symptoms and ocular surface staining.

The viscous and mucoadhesive properties as well as Methyl cellulose anionic charge allow prolonged retention time in the ocular surface.
Methyl cellulose is the most commonly used salt.

Methyl cellulose is one of the important modified cellulose, a water-soluble cellulose, which is widely used in many application of food, pharmaceuticals, detergent, paper coating, dispersing agent, and others.
Methyl cellulose addition possibly increases the hydrogenation and dehydrogenation features of Magnesium.

Methyl cellulose is a thickening agent that is made by reacting cellulose (wood pulp, cotton lint) with a derivative of acetic acid (the acid in vinegar).
Methyl cellulose is also called E 466.

Methyl cellulose has long been considered safe, but a 2015 study funded by the National Institutes of Health raised some doubts.
Methyl cellulose found that both Methyl cellulose and another emulsifier (polysorbate 80) affected gut bacteria and triggered inflam­matory bowel disease symptoms and other changes in the gut, as well as obesity and a set of obesity-related disease risk factors known as metabolic syndrome.

In mice that were predisposed to colitis, the emulsifiers promoted the disease.
Methyl cellulose is possible that polysorbates, Methyl cellulose, and other emulsifiers act like detergents to disrupt the mucous layer that lines the gut, and that the results of the study may apply to other emulsifiers as well.
Research is needed to determine long-term effects of these and other emulsifiers at levels that people consume.

Methyl cellulose is not absorbed or digested, so the FDA allows Methyl cellulose to be included with “dietary fiber” on food labels.
Methyl cellulose isn’t as healthful as fiber that comes from natural foods.

Methyl cellulose is an anionic water-soluble polymer based on renewable cellulosic raw material.
Methyl cellulose functions as a rheology modifier, binder, dispersant, and an excellent film former.
These attributes make Methyl cellulose a preferred choice as a bio-based hydrocolloid in multiple applications.

Methyl cellulose or E 466 is a cellulose derivative with carboxymethyl groups (-CH2-COOH) bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone.
Methyl cellulose, Sodium Salt is the most often used form of E 466.

Methyl cellulose is used in a variety of industries as a thickener and/or to prepare stable emulsions in both food and non-food products.
Insoluble microgranular Methyl cellulose is used as a cation-exchange resin in ion-exchange chromatography for purification of proteins.
Methyl cellulose has also been used extensively to characterize enzyme activity from endoglucanases (part of the cellulase complex).

Methyl cellulose can be used to stabilize palladized iron nanoparticles, which can further be utilized in the dichlorination of contaminated subsurfaces.
Methyl cellulose may also be used as a polymeric matrix to form a composite with a crystalline nanofibril for the development of sustainable bio-based polymers.
Methyl cellulose can also bind with a hard carbon electrode for the fabrication of sodium ion-batteries.

Methyl cellulose is a water dispersible sodium salt of carboxy-methyl ether of cellulose that forms a clear colloidal solution.
Methyl cellulose is a hygroscopic material that has the ability to absorb more than 50% of water at high humidity.
Methyl cellulose is also a natural polymeric derivative that can be used in detergents, food and textile industries.

Methyl cellulose is an anionic polymer with a clarified solution dissolved in cold or hot water.
Methyl cellulose functions as a thickening rheology modifier, moisture retention agent, texture/body building agent, suspension agent, and binding agent in personal products and toothpaste.

Adding Methyl cellulose into toothpaste has obvious effects in binding and body structure.
Due to Methyl cellulose's good uniform substitution ability, excellent salt tolerance and acid resistance, the toothpaste can be easily extruded and show better appearance, and impart a smooth and comfortable toothfeel.

Methyl cellulose, sodium appears as white, fibrous, free-flowing powder, and is used commonly as an FDA-approved disintegrant in pharmaceutical manufacturing.
Disintegrants facilitate the breakup of a tablet in the intestinal tract after oral administration.
Without a disintegrant, tablets may not dissolve appropriately and may effect the amount of active ingredient absorbed, thereby decreasing effectiveness.

According to the FDA Select Committee on GRAS food Substances, Methyl cellulose is virtually unabsorbed.
Methyl cellulose is generally regarded as safe when used in normal quantities.

Methyl cellulose is the sodium salt of a carboxymethyl ether of cellulose obtained from plant material.
In essence, Methyl cellulose is a chemically modified cellulose that has a carboxymethyl ether group (-O-CH2-COO-) bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone.

Methyl cellulose is available in different degrees of substitution, generally in the range 0.6 – 0.95 derivatives per monomer unit, and molecular weights.
Commercial grades of Methyl cellulose are supplied as white to almost white, odourless, tasteless, granular powders.

Methyl cellulose is a derivative of cellulose, in which part of the hydroxyl is linked to a carboxymethyl group (–CH2–COOH) as ether.
Methyl celluloses are not soluble in water in an acidic form, but they dissolve well in basic solvents.

They are used, e.g., to monitor filtration or to increase the viscosity of drilling fluids.
Methyl cellulose is available in different viscosity grades and purity levels.

Methyl cellulose is able to form solid gels.
Methyl cellulose also strengthens the effect of emulsifiers and prevents undesirable substantive lumps.

As Methyl cellulose forms robust, smooth films, Methyl cellulose is also used as a coating agent.
Methyl cellulose is the only cellulose derivative that can also form and stabilize foams.

Methyl cellulose is derived from natural cellulose, or plant fibre.
In Methyl cellulose dry form, it’s an odourless and flavourless white, grey or yellow powder that dissolves in water.
When used in cosmetics, Methyl cellulose stops lotions and creams from separating and controls the thickness and texture of liquids, creams and gels.

Methyl cellulose (technically, Carboxymethylcelluloses) is a family of chemically modified cellulose derivatives containing the carboxymethyl ether group (-O-CH2-COO-) bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone.
When Methyl cellulose is recovered and presented as the Sodium salt, the resulting polymer is what is known as Methyl cellulose, and has the general chemical formula, [C6H7O2(OH)x(OCH2COONa)y]n.

Methyl cellulose was discovered shortly after Word War 1 and has been produced commercially since the early 1930s.
Methyl cellulose is produced by treating cellulose with an aqueous sodium hydroxide solution followed by monochloroacetic acid or Methyl cellulose sodium salt.

In a parallel reaction two by-products, sodium chloride and sodium glycolate, are produced.
Once these by-products are removed, high purity Methyl cellulose is obtained.

As a general rule, the obtained material has a slight excess of sodium hydroxide and has to be neutralised.
The neutralisation endpoint can affect the properties of Methyl cellulose.
In the final step, Methyl cellulose is dried, milled to the desired particle size, and packaged.

Food and pharmaceutical grade Methyl cellulose is required by law to contain not less than 99.5% pure Methyl cellulose and a maximum of 0.5% of residual salts (sodium chloride and sodium glycolate).
The degree of substitution (DS) can vary between 0.2-1.5, although Methyl cellulose is generally in the range of 0.6-0.95.

The DS determines the behaviour of Methyl cellulose in water: Grades with DS >0.6 form colloidal solutions in water that are transparent and clear, i.e the higher the content of carboxymethyl groups, the higher the solubility and smoother the solutions obtained.
Methyl cellulose with a DS below 0.6 tends to be only partially soluble.

Methyl cellulose is available as a white to almost white, odourless, tasteless, granular powder.

Methyl cellulose is the sodium salt of a carboxymethyl ether of 13 cellulose.
Methyl cellulose contains not less than 6.0 percent and not more than 12.0 percent of 14 sodium (Na) on the dried basis, corresponding to 0.53 -1.45 degree of 15 substitution.

Applications of Methyl cellulose:
Methyl cellulose (CMC, Cellulose gum, Methylcellulose) is a modified E 466 (Thickener is E461).
Methyl cellulose tends to give clear, slightly gummy, solutions.

They are generally soluble in cold water and insoluble in hot.
Methyl cellulose is used to thicken dry mix beverage, syrups, ripples and ice cream, and also to stabilise ice cream, batters and sour milk.
Methyl cellulose gives moisture retention to cake mixes and water binding and thickening to icings.

Methyl cellulose can be used as a binder in the preparation of graphene nano-platelet based inks for the fabrication of dye sensitized solar cells (DSSCs).
Methyl cellulose can also be used as a viscosity enhancer in the development of tyrosinase based inks for the formation of electrodes for biosensor applications.
Methyl cellulose is used as a support material for a variety of cathodes and anodes for microbial fuel cells.

Methyl cellulose is used as a highly effective additive to improve Methyl cellulose and processing properties in various fields of application - from foodstuffs, cosmetics and pharmaceuticals to products for the paper and textile industries.

Building material additives, printing inks, coatings, pharmaceuticals, food, cosmetics, paper or textiles – there’s a long and growing list of applications.
Special-purpose cellulose derivatives produced by Wolff Cellulosics provide invisible yet indispensable benefits in countless everyday products.

Fields of Application:
Our cellulosic products perform all kinds of different functions in the various fields of application.

Their capabilities include:
Water retention
Gelling
Emulsifying
Suspending
Absorbing
Stabilising
Bonding
Forming films

Methyl cellulose is also used in numerous medical applications.

Some examples include:
Device for epistaxis (nose bleeding).
A poly-vinyl chloride (PVC) balloon is covered by Methyl cellulose knitted fabric reinforced by nylon.

The device is soaked in water to form a gel, which is inserted into the nose of the balloon and inflated.
The combination of the inflated balloon and the therapeutic effect of the Methyl cellulose stops the bleeding.

Fabric used as a dressing following ear nose and throat surgical procedures.

Water is added to form a gel, and this gel is inserted into the sinus cavity following surgery.
In ophthalmology, Methyl cellulose is used as a lubricating agent in artificial tears solutions for the treatment of dry eyes.

In veterinary medicine, Methyl cellulose is used in abdominal surgeries in large animals, particularly horses, to prevent the formation of bowel adhesions.

Research applications:
Insoluble Methyl cellulose (water-insoluble) can be used in the purification of proteins, particularly in the form of charged filtration membranes or as granules in cation-exchange resins for ion-exchange chromatography.
Methyl cellulose low solubility is a result of a lower DS value (the number of carboxymethyl groups per anhydroglucose unit in the cellulose chain) compared to soluble Methyl cellulose.

Insoluble Methyl cellulose offers physical properties similar to insoluble cellulose, while the negatively charged carboxylate groups allow Methyl cellulose to bind to positively charged proteins.
Insoluble Methyl cellulose can also be chemically cross-linked to enhance the mechanical strength of Methyl cellulose.

Moreover, Methyl cellulose has been used extensively to characterize enzyme activity from endoglucanases (part of the cellulase complex); Methyl cellulose is a highly specific substrate for endo-acting cellulases, as Methyl cellulose structure has been engineered to decrystallize cellulose and create amorphous sites that are ideal for endoglucanase action.
Methyl cellulose is desirable because the catalysis product (glucose) is easily measured using a reducing sugar assay, such as 3,5-dinitrosalicylic acid.

Using Methyl cellulose in enzyme assays is especially important in screening for cellulase enzymes that are needed for more efficient cellulosic ethanol conversion.
Methyl cellulose was misused in early work with cellulase enzymes, as many had associated whole cellulase activity with Methyl cellulose hydrolysis.
As the mechanism of cellulose depolymerization became better understood, Methyl cellulose became clear that exo-cellulases are dominant in the degradation of crystalline (e.g. Avicel) and not soluble (e.g. Methyl cellulose) cellulose.

In food applications:
Methyl cellulose is used as a stabiliser, thickener, film former, suspending agent and extender.
Applications include ice cream, dressings, pies, sauces, and puddings.
Methyl cellulose is available in various viscosities depending on the function Methyl cellulose is to serve.

In non food applications:
Methyl cellulose is sold under a variety of trade names and is used as a thickener and emulsifier in various cosmetic products, and also as a treatment of constipation.
Like cellulose, Methyl cellulose is not digestible, not toxic, and not allergenic.
Some practitioners are using this for weight loss.

Treatment of constipation:
When eaten, methylcellulose is not absorbed by the intestines but passes through the digestive tract undisturbed.
Methyl cellulose attracts large amounts of water into the colon, producing a softer and bulkier stool.

Methyl cellulose is used to treat constipation, diverticulosis, hemorrhoids and irritable bowel syndrome.
Methyl cellulose should be taken with sufficient amounts of fluid to prevent dehydration.
Because Methyl cellulose absorbs water and potentially toxic materials and increases viscosity, Methyl cellulose can also be used to treat diarrhea.

Lubricant:
Methylcellulose is used as a variable viscosity personal lubricant; Methyl cellulose is the main ingredient in K-Y Jelly.

Artificial tears and saliva:
Solutions containing methylcellulose or similar cellulose derivatives are used as substitute for tears or saliva if the natural production of these fluids is disturbed.

Paper and textile sizing:
Methylcellulose is used as sizing in the production of papers and textiles.
Methyl cellulose protects the fibers from absorbing water or oil.

Special effects:
The slimy, gooey appearance of an appropriate preparation of methylcellulose with water, in addition to Methyl cellulose non-toxic, non-allergenic, and edible properties, makes Methyl cellulose popular for use in special effects for motion pictures and television wherever vile slimes must be simulated.
In the film Ghostbusters, for example, the gooey substance that supernatural entities used to “slime” the Ghostbusters was mostly a thick water solution of methylcellulose.

Methyl cellulose is also often used in the pornographic industry to simulate semen in large quantity, in order to shoot movies related to bukkake fetish.
Methyl cellulose is preferable to food-based fake semen (e.g., condensed milk) because this last solution can often cause problems, especially when the ingredient used contains sugar.
Sugar is thought to encourage yeast infection when Methyl cellulose is injected in the vagina.

Applications in Pharmaceutical Formulations or Technology:
Methyl cellulose (technically, Carboxymethylcelluloses) is a family of chemically modified cellulose derivatives containing the carboxymethyl ether group (-O-CH2-COO-) bound to some of the hydroxyl groups of the glucopyranose monomers that make up the cellulose backbone.
When Methyl cellulose is recovered and presented as the Sodium salt, the resulting polymer is what is known as Methyl cellulose, and has the general chemical formula, [C6H7O2(OH)x(OCH2COONa)y]n.

Methyl cellulose was discovered shortly after Word War 1 and has been produced commercially since the early 1930s.
Methyl cellulose is produced by treating cellulose with an aqueous sodium hydroxide solution followed by monochloroacetic acid or Methyl cellulose sodium salt.

In a parallel reaction two by-products, sodium chloride and sodium glycolate, are produced.
Once these by-products are removed, high purity Sodium Methyl cellulose is obtained.

As a general rule, the obtained material has a slight excess of sodium hydroxide and has to be neutralised.
The neutralisation endpoint can affect the properties of Methyl cellulose.
In the final step, Methyl cellulose is dried, milled to the desired particle size, and packaged.

Food and pharmaceutical grade Methyl cellulose is required by law to contain not less than 99.5% pure Methyl cellulose and a maximum of 0.5% of residual salts (sodium chloride and sodium glycolate).
The degree of substitution (DS) can vary between 0.2-1.5, although Methyl cellulose is generally in the range of 0.6-0.95.

The DS determines the behaviour of Methyl cellulose in water: Grades with DS >0.6 form colloidal solutions in water that are transparent and clear, i.e the higher the content of carboxymethyl groups, the higher the solubility and smoother the solutions obtained.
Methyl cellulose with a DS below 0.6 tends to be only partially soluble.

Methyl cellulose is available as a white to almost white, odourless, tasteless, granular powder.

Uses of Methyl cellulose:
Methyl cellulose is used in drilling muds, detergents, resin emulsion paints, adhesives, printing inks, and textile sizes.
Methyl cellulose is also used as a protective colloid, a stabilizer for foods, and a pharmaceutical additive.

Methyl cellulose is used as a bulk laxative, emulsifier and thickener in cosmetics and pharmaceuticals, and stabilizer for reagents.
Methyl cellulose is formerly registered in the US for use as an insecticide for ornamental and flowering plants.

Methyl cellulose is permitted for use as an inert ingredient in non-food pesticide products.
Methyl cellulose is used as an anticaking agent, drying agent, emulsifier, formulation aid, humectant, stabilizer or thickener, and texturizer in foods.

Introduction:
Methyl cellulose is used in a variety of applications ranging from food production to medical treatments.
Methyl cellulose is commonly used as a viscosity modifier or thickener, and to stabilize emulsions in various products, both food and non-food.

Methyl cellulose is used primarily because Methyl cellulose has high viscosity, is nontoxic, and is generally considered to be hypoallergenic, as the major source fiber is either softwood pulp or cotton linter.
Non-food products include products such as toothpaste, laxatives, diet pills, water-based paints, detergents, textile sizing, reusable heat packs, various paper products, filtration materials, synthetic membranes, wound healing applications, and also in leather crafting to help burnish edges.

Food science:
Methyl cellulose is used in food under the E number E466 or E469 (when Methyl cellulose is enzymatically hydrolyzed), as a viscosity modifier or thickener, and to stabilize emulsions in various products, including ice cream.
Methyl cellulose is also used extensively in gluten-free and reduced-fat food products.

Methyl cellulose is used to achieve tartrate or cold stability in wine, an innovation that may save megawatts of electricity used to chill wine in warm climates.
Methyl cellulose is more stable than metatartaric acid and is very effective in inhibiting tartrate precipitation.
Methyl cellulose is reported that KHT crystals, in presence of Methyl cellulose, grow slower and change their morphology.

Their shape becomes flatter because they lose 2 of the 7 faces, changing their dimensions.
Methyl cellulose molecules, negatively charged at wine pH, interact with the electropositive surface of the crystals, where potassium ions are accumulated.
The slower growth of the crystals and the modification of their shape are caused by the competition between Methyl cellulose molecules and bitartrate ions for binding to the KHT crystals.

Specific culinary uses:
Methyl cellulose powder is widely used in the ice cream industry, to make ice creams without churning or extremely low temperatures, thereby eliminating the need for conventional churners or salt ice mixes.
Methyl cellulose is used in baking breads and cakes.
The use of Methyl cellulose gives the loaf an improved quality at a reduced cost, by reducing the need of fat.

Methyl cellulose is also used as an emulsifier in biscuits.
By dispersing fat uniformly in the dough, Methyl cellulose improves the release of the dough from the moulds and cutters, achieving well-shaped biscuits without any distorted edges.
Methyl cellulose can also help to reduce the amount of egg yolk or fat used in making the biscuits.

Use of Methyl cellulose in candy preparation ensures smooth dispersion in flavor oils, and improves texture and quality.
Methyl cellulose is used in chewing gums, margarines and peanut butter as an emulsifier.

Other uses:
In laundry detergents, Methyl cellulose is used as a soil suspension polymer designed to deposit onto cotton and other cellulosic fabrics, creating a negatively charged barrier to soils in the wash solution.
Methyl cellulose is also used as a thickening agent, for example, in the oil-drilling industry as an ingredient of drilling mud, where Methyl celluloseacts as a viscosity modifier and water retention agent.

Methyl cellulose is sometimes used as an electrode binder in advanced battery applications (i.e. lithium ion batteries), especially with graphite anodes.
Methyl cellulose's water solubility allows for less toxic and costly processing than with non-water-soluble binders, like the traditional polyvinylidene fluoride (PVDF), which requires toxic n-methylpyrrolidone (NMP) for processing.
Methyl cellulose is often used in conjunction with styrene-butadiene rubber (SBR) for electrodes requiring extra flexibility, e.g. for use with silicon-containing anodes.

Methyl cellulose is also used in ice packs to form a eutectic mixture resulting in a lower freezing point, and therefore more cooling capacity than ice.

Aqueous solutions of Methyl cellulose have also been used to disperse carbon nanotubes, where the long Methyl cellulose molecules are thought to wrap around the nanotubes, allowing them to be dispersed in water.

In conservation-restoration, Methyl celluloseis used as an adhesive or fixative (commercial name Walocel, Klucel).

Industrial Processes with risk of exposure:
Petroleum Production and Refining
Textiles (Fiber & Fabric Manufacturing)
Painting (Pigments, Binders, and Biocides)
Working with Glues and Adhesives
Farming (Pesticides)

Adverse reactions of Methyl cellulose:
Effects on inflammation, microbiota-related metabolic syndrome, and colitis are a subject of research.
Methyl cellulose is suggested as a possible cause of inflammation of the gut, through alteration of the human gastrointestinal microbiota, and has been suggested as a triggering factor in inflammatory bowel diseases such as ulcerative colitis and Crohn's disease.

While thought to be uncommon, case reports of severe reactions to Methyl cellulose exist.
Skin testing is believed to be a useful diagnostic tool for this purpose.
Methyl cellulose was the active ingredient in an eye drop brand Ezricare Artificial Tears which was recalled due to potential bacterial contamination.

Preparation of Methyl cellulose:
Methyl cellulose is synthesized by the alkali-catalyzed reaction of cellulose with chloroacetic acid.
The polar (organic acid) carboxyl groups render the cellulose soluble and chemically reactive.
Fabrics made of cellulose—e.g. cotton or viscose rayon—may also be converted into Methyl cellulose.

Following the initial reaction, the resultant mixture produces approximately 60% Methyl cellulose and 40% salts (sodium chloride and sodium glycolate).
Methyl cellulose is the so-called technical Methyl cellulose, which is used in detergents.

An additional purification process is used to remove salts to produce pure Methyl cellulose, which is used for alimentary and pharmaceutical applications.
An intermediate "semi-purified" grade is also produced, typically used in paper applications such as the restoration of archival documents.

Structure and properties of Methyl cellulose:
The functional properties of Methyl cellulose depend on the degree of substitution of the cellulose structure [i.e., how many of the hydroxyl groups have been converted to carboxymethylene(oxy) groups in the substitution reaction], as well as the chain length of the cellulose backbone structure and the degree of clustering of the carboxymethyl substituents.

Structure:
Methyl cellulose is typical ionic-type cellulose ether and the frequently used product is Methyl cellulose sodium salt, as well as ammonium and aluminum salts.
Sometimes, Methyl cellulose acids can be produced.

When degree of substitution (that is, the average value of hydroxyl groups reacted with the substitution of each anhydrous glucose monomer) is 1, Methyl cellulose molecular formula is [C6H7O2 (OH) 2OCH2COONa] n.
With drying at the temperature of 105℃ and constant weight, the content of sodium is 6.98-8.5%.

Appearance and Solubility:
The pure Methyl cellulose is white or milk white fibrous powder or particles, odorless and tasteless.
Methyl celluloseis insoluble in organic solvents such as methanol, alcohol, diethyl ether, acetone, chloroform and benzene but soluble in water.
Degree of substitution is an important factor influencing water solubility and the viscosity of Methyl cellulose also has a great effect on the water solubility.

In general when the viscosity is within 25-50Pa•s and the degree of substitution is about 0.3, Methyl celluloseshows alkaline solubility and while the degree of substitution is over 0.4, Methyl celluloseshows water solubility.
With the rise of DS, the transparency of solution improves accordingly.
In addition, the replacement homogeneity also has an great effect on the solubility.

Hygroscopicity:
Methyl cellulose equilibrium water content will increase with the rise of air humidity but decrease with the rise of temperature.
At room temperature and average humidity of 80-85%, the equilibrium water content is more than 26% but moisture content in Methyl celluloses is lower than 10%, lower than the former.
As far as Methyl cellulose shape is concerned, even if the water content is about 15%, there seems no difference in appearance.

However, when the moisture content reaches above 20%, inter-particle mutual adhesion can be perceived and the higher the viscosity is, the more evident Methyl cellulosewill become.
For these polarized high-molecular compounds like Methyl cellulose, the hygroscopic degree is not only affected by the relative humidity but also by the number of polarity.

The higher the degree os substitution is, that is, the larger the number of polarity, the stronger the hygroscopicity will be.
Moreover, crystallinity also affects Methyl celluloseand the higher the crystallinity is, the smaller the hygroscopic will be.

Compatibility:
Methyl cellulose has good compatibility with other kinds of water-soluble glues, softeners and resin.
For example, Methyl celluloseis compatible with animal glues, dimethoxy dimethylurea gel, Arabic gum, pectin, tragacanth gum, ethylene glycol, sorbitol, glycerol, invert sugar, soluble starch and sodium alginate.



Methyl celluloseis also compatible with casein, Methyl cellulose of melamine- formaldehyde resin and ethylene glycol, urea formaldehyde ethylene glycol resin, methyl cellulose, polyvinyl alcohol (PVA), phosphate nitrilotriacetic acid, and sodium silicate but the degree is slightly poorer.
1% Methyl cellulose solution is compatible with most inorganic salts.

Dissociation Constant:
In the giant polymer matrix of Methyl cellulose, there are plenty of electrolyzing groups (carboxymethyl groups).
The acidity is similar to that of acetic acid and the dissociation constant is 5×10-5.
The dissociation strength has an considerable effect on the electrical properties of Methyl cellulose.

Biochemical Properties:
Although Methyl cellulose solution is difficult to get rotten than natural gums, under certain conditions, some microbes enable Methyl celluloseto get rotten, especially with cellulose and taka-amylase reactions, leading to the decrease of solution viscosity.
The higher the DS of Methyl cellulose is, the less Methyl cellulosewill be affected by enzymes and this is because the side chain linked with glucose residues prevents enzymolysis.

Since the enzyme action leads to the breakage of Methyl cellulose main chain and generates reducing sugar, in this way the degree of polymerization will decrease and the solution viscosity will accordingly decrease.
The digestive enzymes within human body can have no decomposition on Methyl cellulose and Methyl cellulose has no decomposition in acid or alkaline digestive juice.

Handling and storage of Methyl cellulose:

Conditions for safe storage, including any incompatibilities:

Storage conditions:
Tightly closed.
Dry.

Stability and reactivity of Methyl cellulose:

Reactivity:
The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Chemical stability:
Methyl cellulose is chemically stable under standard ambient conditions (room temperature).

Possibility of hazardous reactions:

Violent reactions possible with:
strong oxidising agents

Conditions to avoid:
no information available

Incompatible materials:
No data available

First aid measures of Methyl cellulose:

If inhaled:

After inhalation:
Fresh air.

In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.

In case of eye contact:

After eye contact:
Rinse out with plenty of water.
Remove contact lenses.

If swallowed:

After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.

Indication of any immediate medical attention and special treatment needed:
No data available

Firefighting measures of Methyl cellulose:

Suitable extinguishing media:
Water Foam Carbon dioxide (CO2) Dry powder

Unsuitable extinguishing media:
For Methyl cellulose no limitations of extinguishing agents are given.

Special hazards arising from Methyl cellulose or mixture:
Nature of decomposition products not known.
Combustible.
Development of hazardous combustion gases or vapours possible in the event of fire.

Advice for firefighters:
In the event of fire, wear self-contained breathing apparatus.

Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.

Accidental release measures of Methyl cellulose:

Personal precautions, protective equipment and emergency procedures:

Advice for non-emergency personnel:
Avoid inhalation of dusts.
Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental precautions:
Do not let product enter drains.

Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.

Observe possible material restrictions.
Take up dry.

Dispose of properly.
Clean up affected area.
Avoid generation of dusts.

Identifiers of Methyl cellulose:
CAS Number: 9004-32-4
ChEBI: CHEBI:85146
ChEMBL: ChEMBL1909054
ChemSpider: none
ECHA InfoCard: 100.120.377
E number: E466 (thickeners, ...)
UNII: 05JZI7B19X
CompTox Dashboard (EPA): DTXSID7040441

EC / List no.: 618-378-6
CAS no.: 9004-32-4

Synonym(s): Carboxymethylcellulose sodium salt
CAS Number: 9004-32-4
MDL number: MFCD00081472
NACRES: NA.23

ChEBI: CHEBI:85146
ChEMBL: ChEMBL1909054
ChemSpider: none
ECHA InfoCard: 100.120.377
E number: E466 (thickeners, ...)
UNII: 05JZI7B19X
CompTox Dashboard (EPA): DTXSID7040441
Chemical formula: C8H15NaO8
Molar mass: variable
SMILES: CC(=O)[O-].C(C(C(C(C(C=O)O)O)O)O)O.[Na+]
InChI Key: QMGYPNKICQJHLN-UHFFFAOYSA-M
InChI: InChI=1S/C6H12O6.C2H4O2.Na/c7-1-3(9)5(11)6(12)4(10)2-8;1-2(3)4;/h1,3-6,8-12H,2H2;1H3,(H,3,4);/q;;+1/p-1

Product Number: C0603
Molecular Formula / Molecular Weight: [C6H7O2(OH)x(OCH2COONa)y]__n
Physical State (20 deg.C): Solid
Store Under Inert Gas: Store under inert gas
Condition to Avoid: Hygroscopic
CAS RN: 9004-32-4
Merck Index (14): 1829
MDL Number: MFCD00081472

Physical state at 20 °C: Solid:
Colour: Almost white powder:
Odour: Odorless
pH value: 6.5 - 8.5
Density [g/cm3]: 1.59:
Solubility in water [% weight]: Soluble in water

Physical State: Solid
Solubility: Soluble in water (20 mg/ml).
Storage: Store at room temperature

Properties of Methyl cellulose:
form: powder
Quality Level: 200
autoignition temp.: 698 °F
mol wt: average Mw ~700,000
extent of labeling: 0.9 carboxymethyl groups per anhydroglucose unit
mp: 270 °C (dec.)
InChI: 1S/C6H12O6.C2H4O2.Na/c7-1-3(9)5(11)6(12)4(10)2-8;1-2(3)4;/h1,3-6,8-12H,2H2;1H3,(H,3,4);
InChI key: DPXJVFZANSGRMM-UHFFFAOYSA-N

logP: -3.6:
pKa (Strongest Acidic): 11.8
pKa (Strongest Basic): -3
Physiological Charge: 0
Hydrogen Acceptor Count: 6
Hydrogen Donor Count: 5
Polar Surface Area: 118.22 Ų
Rotatable Bond Count: 5
Refractivity: 37.35 m³·mol⁻¹
Polarizability: 16.07 ų
Number of Rings: 0
Bioavailability: Yes
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: No
MDDR-like Rule: No

Appearance: Off white to cream colored powder
Assay (as Na; HClO4 titration, on anhydrous basis): 6.5 - 9.5%
Identity: Passes test
pH (1% solution): 6.5 - 8.0
Viscosity (1% solution; 20°C on dried basis): 250 - 350 cps
Appearance of solution: Passes test
Insoluble matter in water: Passes test
Loss on drying (at 105°C): Max 10%
Sulphated Ash (as SO4; on dried basis): 20 - 29.3%
Chloride (Cl): Max 0.25%
Sodium glycolate: Max 0.4%
Heavy metal (as Pb): Max 0.002%
Arsenic (As): Max 0.0003%
Iron (Fe): Max 0.02%

Condition to Avoid: Hygroscopic
Content(Na,Drying substance): 6.0 to 8.5 %
Drying loss: max. 10.0 %
Etherification value( as Drying substance): 0.5 to 0.8
Merck Index (14): 1829
Physical State (20 deg.C): Solid
PubChem Substance ID: 87565248
RTECS#: FJ5950000
Store Under Inert Gas: Store under inert gas
Viscosity: 500.0 to 900.0 mPa-s(2 %, H2O, 25 deg-C)

Molecular Weight: 262.19 g/mol
Hydrogen Bond Donor Count: 5
Hydrogen Bond Acceptor Count: 8
Rotatable Bond Count: 5
Exact Mass: 262.06646171 g/mol
Monoisotopic Mass: 262.06646171 g/mol
Topological Polar Surface Area: 158Ų
Heavy Atom Count: 17
Complexity: 173
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 4
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes

Specifications of Methyl cellulose:
Appearance: White to Light yellow to Light orange powder to crystal
Content(Na,Drying substance): 6.0 to 8.5 %
Etherification value( as Drying substance): 0.5 to 0.8
Drying loss: max. 10.0 %
Viscosity: 900 to 1400 mPa-s(1 %, H2O, 25 deg-C)
FooDB Name: Carboxymethyl cellulose, sodium salt

Names of Methyl cellulose:

Regulatory process name:
Cellulose, carboxymethyl ether, sodium salt

IUPAC names:
2,3,4,5,6-pentahydroxyhexanal acetic acid sodium hydride
acetic acid; 2,3,4,5,6-pentahydroxyhexanal; sodium
Carboximethilcelullose
Carboxymethyl cellulose
Carboxymethyl Cellulose Sodium
Carboxymethyl cellulose sodium salt
Carboxymethyl cellulose, sodium salt
Carboxymethylcellulose
carboxymethylcellulose
Carboxymethylcellulose sodium salt
Cellulose carboxymethyl ether sodium salt
Cellulose Gum
Cellulose gum
Cellulose, carboxymethyl ether, sodium salt
Na carboxymethyl cellulose
sodium carboxy methyl cellulose
sodium carboxyl methyl cellulose
SODIUM CARBOXYMETHYL CELLULOSE
Sodium Carboxymethylcellulose
Sodium carboxymethylcellulose
sodium cellulose carboxymethyl ether

Trade name:
Carboximetilcelulosa

Other names:
Carboxy methyl cellulose sodium
Carboxymethyl cellulose
carboxymethyl cellulose sodium salt
carboxymethyl cellulose sodium salts
Carboxymethyl ether cellulose sodium salt
Carboxymethylcellulose Sodium Salt
Carboxymethylcellulose, sodium salt
cellulose carboxymethyl ether sodium salt
Cellulose, Carboxymethyl ether, Sodiu
SODIUM CARBOXYMETHYL CELLULOSE
Sodium carboxymethyl cellulose
Sodium Carboxymethylcellulose
Carboxymethylcellulose
carmellose
E466

Other identifier:
9004-32-4
Methyl cellulose ether ( Méthylcellulose)
METHYL DIHYDROXYBENZOATE N° CAS : 2150-46-1 Nom INCI : METHYL DIHYDROXYBENZOATE Nom chimique : Benzoic acid, 2,5-Dihydroxy-, Methyl Ester N° EINECS/ELINCS : 218-427-8 Ses fonctions (INCI) Agent de chélation : Réagit et forme des complexes avec des ions métalliques qui pourraient affecter la stabilité et / ou l'apparence des produits cosmétiques
METHYL CHLORO ISOTHIAZOLINONE
5-Chloro-2-methyl-4-isothiazolin-3-one; Kathon CG; 5-Cloro-2-metil-2H-isotiazol-3-ona (Spanish); 5-Chloro2-méthyl-2H-isothiazole-3-one (French); Methylchloroisothiazolinone; 5-Chloro-2-methyl-3(2H)-isothiazolone; 5-Chloro-2-methyl-3(2H)-isothiazolone; CAS NO : 26172-55-4
Methyl Chloro Isothiazolinone Methyl Isothiazolinone (CIT/MIT)
SYNONYMS Isothiazolinone chloride; Kathon 886; Kathon CG; CMIT/MIT mixture; 5-Chloro-2-methyl-3(2H)-isothiazolone mixt. with 2-methyl-3(2H)-isothiazolone; Chloromethylisothiazolione/Methylisothiazolinone (75%/25%); CMI/MI; MCI/MI; CIT/MIT; Microcare IT; Microcare ITL; Acticide 14; Acticide LGMicrocide III; ProClin 300; Slaoff 360; Somacide RS; Tret-O-Lite XC 215; Zonen F; CAS NO. 55965-84-9
METHYL DIHYDROXYBENZOATE
METHYL ETHYL KETONE; MEK; Methyl Acetone; Oxobutane; 2-Butanone; butan-2-one; Butanone; Ethyl methyl ketone; cas no: 78-93-3
METHYL DIPROXITOL
DESCRIPTION:

Methyl Diproxitol is a colourless, hygroscopic,high boiling liquid with a mild odour.
Methyl Diproxitol is miscible in any proportion with water and many organic solvents and has a good solvent power for nitrocellulose and dyestuffs.
Methyl Diproxitol is used in the following products: coating products, anti-freeze products and lubricants and greases.


CAS NUMBER: 34590-94-8

EC NUMBER: 252-104-2

MOLECULAR FORMULA: C7H16O3

MOLECULAR WEIGHT: 148,21



DESCRIPTION:

Methyl Diproxitol is a colorless, viscous liquid with a faint odour.
Methyl Diproxitol has moderate volatility and is completely soluble in water.
Methyl Diproxitol is used as solvent, chemical intermediate and coupling agent.
Methyl Diproxitol is solvent for paints, varnishes, alkyds, epoxies, polyesters, varnishes, strippers, inks, solvent-based coatings, lacquers, nitrocellulose and synthetic resins, insect repellents, waxes, adhesives, coatings, agricultural products, printing inks.

Methyl Diproxitol is used as a coupling agent in water-based paints, inks, container painting fabrics, floor polishes.
Methyl Diproxitol is used as a solvent and chemical intermediate for cleaners, coatings, paints, automotive fluids, agricultural products, waxes, adhesives, insect repellents, cosmetics.
Methyl Diproxitol is used as solvent for DPM, PVC stabilizer, nitrocellulose, ethyl cellulose.

Methyl Diproxitol is a colourless, hygroscopic, high boiling liquid with a mild odour.
Methyl Diproxitol is miscible in any proportion with water and many organic solvents and has good solvent power for nitrocellulose and dyestuffs.
Methyl Diproxitol is a propylene oxide-based glycol ether with the formula C7H16O3.
Methyl Diproxitol is a clear, colourless, viscous liquid which has a slight ether odour.

Methyl Diproxitol is completely soluble in water and is miscible with a number of organic solvents, for example, ethanol, carbon tetrachloride, benzene, petroleum ether and monochlorobenzene.
Methyl Diproxitol is also practically non-toxic and hygroscopic.
These properties make it extremely suitable for both household, commercial and industrial use.

Methyl Diproxitol is also widely used as a solvent in the production of coatings, including automotive and industrial coatings.
Methyl Diproxitol is an effective solvent for a wide range of resins, including acrylics, epoxies, and polyesters.
Methyl Diproxitol improves the flow and levelling properties of coatings, which enhances their appearance and performance.
Methyl Diproxitol also enhances the adhesion of coatings to substrates, improving their durability and resistance to abrasion, corrosion, and weathering.




USAGE:

-Industrial, automotive and architectural coatings
-resins
-Coating formulation and application
-cleaners



PROPERTIES:

-Cas No: 34590-94-8
-EINECS No: 252-104-2
-Chemical Formula: C7H16O3
-Appearance: Colurless Liquid
-Purity, %: 99,85
-Density (Kg/Lt): 0,951
-Flash Point, °C: 74 °C
-Boiling Point, °C: 190 °C
-Acidity, %: 0,001
-Molecular Weight: 148,21



PROPERTIES:

-Appearance: liquid
-Colour: clear
-Odour: Ethereal
-Melting / freezing point: -83 °C
-Boiling point/boiling range: 184 - 190 °C
-Flash point: 75 °C
-Method: ASTM D-93 / PMCC
-Evaporation rate: 0,01
-Method: ASTM D 3539, nBuAc=1
-Upper explosion limit: 14 %(V)
-Lower explosion limit: 1,1 %(V)
-Vapour pressure: 37,1 Pa (25 °C)
-Relative vapour density: Data not available
-Relative density: 0,95 - 0,96 (20 °C)
-Density: 952 - 956 kg/m3 (20 °C)
-Method: ASTM D4052
-Solubility(ies)
-Water solubility: completely soluble (25 °C)



PHYSICAL PROPERTIES:

-Molecular Weight: 148.2 (g/mol)
-Density (20 °C): 0.95 g/cm3
-pH: 4.5 – 7.0



FIRST AID:

-If inhaled:

No treatment necessary under normal conditions of use.
If symptoms persist, obtain medical advice.


-In case of skin contact:

Remove contaminated clothing. Flush exposed area with
water and follow by washing with soap if available.
If persistent irritation occurs, obtain medical attention.


-In case of eye contact:

Flush eye with copious quantities of water.
Remove contact lenses, if present and easy to do. Continue
rinsing.
If persistent irritation occurs, obtain medical attention.


-If swallowed:

In general no treatment is necessary unless large quantities
are swallowed, however, get medical advice.




























METHYL DIPROXITOL GLYCOL ETHER
Methyl Diproxitol Glycol Ether is an organic solvent with a variety of industrial and commercial uses.
Methyl Diproxitol Glycol Ether finds use as a less volatile alternative to propylene glycol methyl ether and other glycol ethers.
The commercial product is typically a mixture of four isomers.


CAS NUMBER: 34590-94-8

EC NUMBER: -

MOLECULAR FORMULA: C7H16O3

MOLECULAR WEIGHT: 148.20 g/mol

IUPAC NAME: 2-(2-methoxypropoxy)propan-1-ol



Methyl Diproxitol Glycol Ether is an organic solvent used in various applications such as ceramic ink preparation, etching, and bioactive glass suspension
Methyl Diproxitol Glycol Ether acetate, mixture of isomers is a monohydric alcohol that is used as an additive in cosmetics and pharmaceutical products.

Methyl Diproxitol Glycol Ether has good solvency for water-insoluble substances such as silicone oils, n-butyl alcohol, and methyl alcohol.
Methyl Diproxitol Glycol Ether, mixture of isomers can also be used as a solvent for in vitro tests.

With its low viscosity and high boiling point (at atmospheric pressure), it can be used at temperatures between -20 °C to 120 °C.
Methyl Diproxitol Glycol Ether is used as a coupling agent for water-based dilutable coatings.

Methyl Diproxitol Glycol Ether is often found in blends.
Methyl Diproxitol Glycol Ether is an active solvent for solvent-based coatings.

Methyl Diproxitol Glycol Ether is used in household and industrial cleaners
Methyl Diproxitol Glycol Ether can be found in the structure of oil and paint removers.

Methyl Diproxitol Glycol Ether is also used as a binder for water-based paints and inks.
Methyl Diproxitol Glycol Ether promotes polymer fusion during the drying process in the paint industry.
Methyl Diproxitol Glycol Ether also works in wood and roll coatings.

Methyl Diproxitol Glycol Ether is a chemical that is frequently used in the automotive industry.
Methyl Diproxitol Glycol Ether is also a component of coatings used in industrial maintenance and metal plating.

Methyl Diproxitol Glycol Ether is a substance often used in the manufacture of metal cleaners.
Methyl Diproxitol Glycol Ether acts as a coupling agent in hard surface cleaners

Methyl Diproxitol Glycol Ether functions as a solvent
Methyl Diproxitol Glycol Ether is used as a solvent for solvent-based gravure and flexographic printing inks

Methyl Diproxitol Glycol Ether is the primary solvent used in solvent-based screen printing inks.
Methyl Diproxitol Glycol Ether is a coupling agent in solvent blends for water-based gravure, flexographic and screen printing inks.

Methyl Diproxitol Glycol Ether acts as bonding agent for boat dyeing fabrics
Methyl Diproxitol Glycol Ether can be used as a co-solvent in cosmetic formulations

Methyl Diproxitol Glycol Ether is also used as a binder and softener substitute in cosmetics production.
Methyl Diproxitol Glycol Ether is stabilizer for agricultural herbicides
Methyl Diproxitol Glycol Ether acts as a binder for floor finishes

Features of Methyl Diproxitol Glycol Ether
• It has strong solvency
• It has a moderate evaporation rate
• Low viscosity
• It has a high dilution rate
• It is a substance with low surface tension
• Connectivity capability
• It is a solvent with a wide range of applications.

Methyl Diproxitol Glycol Ether has a moderate evaporation rate
Methyl Diproxitol Glycol Ether offers very good bonding abilities and low viscosity.
Methyl Diproxitol Glycol Ether exhibits high dilution rate and low surface tension.

Methyl Diproxitol Glycol Ether is also a component of hydraulic fluids and industrial degreasers.
Methyl Diproxitol Glycol Ether is a solvent often used in petroleum production.

Methyl Diproxitol Glycol Ether is a chemical additive used in the drilling industry.
Methyl Diproxitol Glycol Ether is a very useful chemical building block in the manufacture of many products. Methyl Diproxitol Glycol Ether can be used in ceiling and wall paints

Methyl Diproxitol Glycol Ether also has a softener feature.
Methyl Diproxitol Glycol Ether is used in cosmetic products, floor and aluminum polish where it provides product stabilization.

What is Methyl Diproxitol Glycol Ether?
Methyl Diproxitol Glycol Ether has a slight ether odor
Methyl Diproxitol Glycol Ether is clear and colorless

Methyl Diproxitol Glycol Ether is a viscous liquid.
Methyl Diproxitol Glycol Ether is completely soluble in water

Methyl Diproxitol Glycol Ether is miscible with a number of organic solvents such as ethanol, carbon tetrachloride, benzene, petroleum ether and monochlorobenzene.
Methyl Diproxitol Glycol Ether is also practically non-toxic

Methyl Diproxitol Glycol Ether is hygroscopic
Methyl Diproxitol Glycol Ether is suitable for commercial and industrial use.

Usage Areas of Methyl Diproxitol Glycol Ether
Methyl Diproxitol Glycol Ether is often included in latex emulsion coatings


PHYSICAL PROPERTIES:

-Molecular Weight: 148.20 g/mol

-XLogP3: -0.1

-Exact Mass: 148.109944368 g/mol

-Monoisotopic Mass: 148.109944368 g/mol

-Topological Polar Surface Area: 38.7Ų

-Physical Description: Colorless liquid with a mild, ether-like odor

-Color: Colorless

-Form: Liquid

-Odour: Ether-like odor

-Boiling Point: 190 °C

-Melting Point: -80 °C

-Flash Point: 85 °C

-Solubility in water: very good

-Density: 0.95

-Vapor Density: 5.11

-Vapor Pressure: 0.5 mmHg

-Autoignition Temperature: 270 °C


Methyl Diproxitol Glycol Ether can be used to prevent shocking (coagulation of the emulsion) when using hydrophobic solvents.
Methyl Diproxitol Glycol Ether's hydrophilic nature makes it an ideal bonding aid in water-reducing coatings and cleaning applications.

The predominant use of Methyl Diproxitol Glycol Ether is in consumer products, including paints, varnishes, inks and cleaning products.
The use of Methyl Diproxitol Glycol Ether as an inert ingredient in pesticide products is also limited as a stabilizer in pesticide formulations applied only to growing crops.


CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 1

-Hydrogen Bond Acceptor Count: 3

-Rotatable Bond Count: 5

-Heavy Atom Count: 10

-Formal Charge: 0

-Complexity: 75.3

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 2

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 1

-Compound Is Canonicalized: Yes

-Chemical Classes: Solvents -> Glycol Ethers (P Series)


Methyl Diproxitol Glycol Ether is used in the manufacture of a wide variety of industrial and commercial products, including paints, varnishes, inks and cleaners.
Methyl Diproxitol Glycol Ether can be used as a solvent in the manufacture of water-based coatings.

Methyl Diproxitol Glycol Ether is used as a binder for water-based paints and inks.
Methyl Diproxitol Glycol Ether is also an intermediate in the production of dipropylene glycol methyl ether acetate (Dipropylene glycol methyl etherA).

Methyl Diproxitol Glycol Ether is widely used in industrial, commercial, automotive and household cleaners.
Methyl Diproxitol Glycol Ether can be found in the structure of glass, surface and all-purpose cleaners.

Methyl Diproxitol Glycol Ether is used in the manufacture of floor polishes and carpet cleaners.
Methyl Diproxitol Glycol Ether is one of the main ingredients in paints and paintbrush cleaners.

Methyl Diproxitol Glycol Ether is involved as a solvent in the manufacture of inks and paints
Methyl Diproxitol Glycol Ether is found in rust remover and aluminum polishing products.
Methyl Diproxitol Glycol Ether is involved in cleaning cosmetics and their residues in packaging.

USES OF Methyl Diproxitol Glycol Ether:
Methyl Diproxitol Glycol Ether is a very useful industrial and commercial chemical.
One of the main commercial uses of Methyl Diproxitol Glycol Ether is as a solvent for paints, varnishes, inks, strippers and degreasers.

Methyl Diproxitol Glycol Ether is also used as a binder for water-based paints and inks.
Methyl Diproxitol Glycol Ether promotes polymer fusion during the drying process.
Methyl Diproxitol Glycol Ether is also a component of wood and roll coatings, as well as coatings used in the automotive industry, industrial maintenance and metal plating.

Methyl Diproxitol Glycol Ether is also a component of hydraulic fluids and industrial degreasers.
Methyl Diproxitol Glycol Ether is a chemical additive used in the oil production and drilling industries.

Methyl Diproxitol Glycol Ether is used in the following products:
-fuels
-laboratory chemicals
-plant protection products

Methyl Diproxitol Glycol Ether is used in the following areas:
-construction and construction works
-printing and reproduction of recorded media
-agriculture
-forestry
-fishery

Methyl Diproxitol Glycol Ether is used in the manufacture of:
-machinery and tools
-furniture
-plastic products
-mineral products (eg plasters, cement)

Methyl Diproxitol Glycol Ether is used in the following products:
-air care products
-plant protection products
-washing and cleaning products
- biocides (e.g. disinfectants, pest control products)
-lubricants and greases
-perfumes and fragrances
-varnishes and waxes
-cosmetics and personal care products

Methyl Diproxitol Glycol Ether is a very useful chemical building block in the manufacture of many products.
This is because it reacts with acids to form esters and oxidizing agents producing aldehydes, carboxylic acids and alkali metals, thus forming alcoholates and acetals.
Methyl Diproxitol Glycol Ether is this flexibility that supports the use of Methyl Diproxitol Glycol Ether in a variety of industries and therefore makes it a component of many household items that people use every day.

Methyl Diproxitol Glycol Ether is found in ceiling and wall paints and many common cleaners, including glass and surface cleaners, paintbrush cleaners, all-purpose cleaners, carpet cleaners, and disinfectant cleaners.
Methyl Diproxitol Glycol Ether is often used in cosmetic products where it also provides emollient properties and product stabilization.

Methyl Diproxitol Glycol Ether is also found in floor and aluminum polish where it acts as a stabilizer.
Methyl Diproxitol Glycol Ether is a solvent used in leather and textile dyes.

Methyl Diproxitol Glycol Ether is an intermediate also found in rust removers and pesticides.
Methyl Diproxitol Glycol Ether is also a chemical intermediate in the production of Dipropylene glycol monomethyl ether acetate or Methyl Diproxitol Glycol EtherA.

How is Methyl Diproxitol Glycol Ether produced?
Methyl Diproxitol Glycol Ether is produced by the reaction of propylene oxide with methanol using a catalyst.

How is Methyl Diproxitol Glycol Ether stored and distributed?
Methyl Diproxitol Glycol Ether is stored in mild steel and/or stainless steel tanks and/or drums and can be transported by bulk carriers or tanker trucks.
Methyl Diproxitol Glycol Ether should be stored in a cool, well-ventilated area away from heat and sources of ignition.
Methyl Diproxitol Glycol Ether has a specific gravity of 0.95 and a flash point of 75°C (closed cup) and is not regulated for any mode of transport.

Methyl Diproxitol Glycol Ether is a very useful industrial and commercial chemical.
Methyl Diproxitol Glycol Ether is used as a solvent for degreasers

Methyl Diproxitol Glycol Ether is also a chemical intermediate in the production of Dipropylene glycol monomethyl ether acetate or Methyl Diproxitol Glycol EtherA.
Methyl Diproxitol Glycol Ether can react violently with strong oxidizing agents.
Methyl Diproxitol Glycol Ether can initiate the polymerization of isocyanates and epoxides.

Methyl Diproxitol Glycol Ether is a colorless liquid with a slight odour.
Methyl Diproxitol Glycol Ether is a clear, colorless, flammable liquid with a slight ether odour.

Methyl Diproxitol Glycol Ether is completely soluble in water
Methyl Diproxitol Glycol Ether has moderate volatility.
Methyl Diproxitol Glycol Ether is a propylene oxide-based or P-series glycol ether.


SYNONYMS:

Methyl Diproxitol Glycol Ether
2-(2-methoxypropoxy)propan-1-ol
Dipropylene glycol methyl ether
13588-28-8
2-(2-METHOXYPROPOXY)-1-PROPANOL
1-Propanol, 2-(2-methoxypropoxy)-
2-(2-methoxypropoxy)propanol
12002-25-4
SCHEMBL16073
dipropyleneglycol monomethyl ether
Propanol, oxybis-, methyl ether
DTXSID80864425
AKOS037648698
NCGC00090688-04
BS-15252
LS-62925
CS-0154037
FT-0625302
D81108
J-019668
J-520393
Q2954819
Propanol, 1(or 2)-(2-methoxymethylethoxy)
1(or 2)-(2-Methoxymethylethoxy)propanol
Dipropylene glycol methyl ether
Methoxypropoxypropanol
METHYL ESTER SULFONATE
Fatty acid methyl ester sulfonate; Methyl ethanesulfonate; ethanesulfonic acid methyl ester; Methyl ethane sulphonate; ETHANESULFONIC ACID, METHYL ESTER; CAS NO : 93348-22-2
METHYL ETHYL KETONE
Methyl Ethyl Ketone is colorless, and has a sharp, sweet odour reminiscent of butterscotch and acetone.
Methyl Ethyl Ketone is an organic compound which is also known as butanone or methylacetone.


CAS Number: 78-93-3
EC Number: 201-159-0
Molecular Formula: C4H8O / CH3COCH2CH3


Methyl Ethyl Ketone is an active & organic solvent.
Methyl Ethyl Ketone is in a clear, inflammable and liquid form.
Methyl Ethyl Ketone is in the ketone groups.


Methyl Ethyl Ketone has a high evaporation rate.
Methyl Ethyl Ketone is one of the most widely used ketones in the industry.
Methyl Ethyl Ketone’s a colourless liquid with a sweet acetone-like smell.


Methyl Ethyl Ketone (CAS 78-93-3) is also known as Butanone.
Methyl Ethyl Ketone is colorless, and has a sharp, sweet odour reminiscent of butterscotch and acetone.
Methyl ethyl ketone is a dialkyl ketone which consists of 4 carbon ketone that carries a single keto group at the C-2 position.


Methyl Ethyl Ketone acts as a bacterial metabolite and polar aprotic solvent.
Methyl Ethyl Ketone is a key fluid in formulating polychloroprene adhesives, especially as a replacement for toluene, and is a component of many gravure printing inks.


Methyl Ethyl Ketone evaporates quickly.
Methyl Ethyl Ketone also known as butanone is a clear, colourless organic liquid compound.
Methyl Ethyl Ketone is highly volatile with a flashpoint of - 4ºC and a boiling point 78ºC.


Methyl Ethyl Ketone has quite a strong distinct smell, a little bit like acetone.
Methyl Ethyl Ketone is soluble in polar and non-polar organic materials, being soluble in alcohol and hydrocarbons.
Methyl Ethyl Ketone has fast evaporating properties.


Methyl Ethyl Ketone (also known as MEK, butanone, 2-butanone, butan-2-one, oxobutane, or methyl acetone) is a clear volatile liquid that is soluble in water and has a mild, acetone odour.
Methyl Ethyl Ketone has the formula C4H8O.


Methyl Ethyl Ketone does occur naturally as it is biosynthesized by some trees and is also found in small amounts in some fruits and vegetables as well as in chicken, honey and a variety of cheeses.
Methyl Ethyl Ketone also known as MEK is a colourless water miscible liquid with a sharp but sweet odour.


Methyl Ethyl Ketone is an organic compound with the formula CH3C(O)CH2CH3.
Methyl Ethyl Ketone acts as a solvent.
Methyl Ethyl Ketone has a low viscosity.


Methyl Ethyl Ketone offers strong solvency and fast evaporation properties.
Methyl Ethyl Ketone is a colorless liquid with a moderately sharp, fragrant, mint- or acetone-like odor.
Methyl Ethyl Ketone is a clear, colourless, volatile, highly flammable liquid with a mint or fruity acetone-like odour.


Other common names of Methyl Ethyl Ketone are butanone, 2-butanone and methyl acetone.
Methyl Ethyl Ketone is a manufactured chemical but it is also present in the environment from natural sources.
Methyl Ethyl Ketone is a colorless liquid with a sharp, sweet odor.


Methyl Ethyl Ketone is also known as methyl ethyl ketone (MEK).
Methyl Ethyl Ketone is produced in large quantities.
Methyl Ethyl Ketone is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 tonnes per annum.


Methyl Ethyl Ketone appears as colorless fairly volatile liquid with a pleasant pungent odor.
The flash point of Methyl Ethyl Ketone is 20 °F.
Methyl Ethyl Ketone's vapors are heavier than air.


Methyl Ethyl Ketone does not react with water or many common materials.
Methyl Ethyl Ketone is stable in normal transportation.
The density of Methyl Ethyl Ketone is 6.7 lb / gal.


Methyl Ethyl Ketone is a dialkyl ketone that is a four-carbon ketone carrying a single keto- group at position C-2.
Methyl Ethyl Ketone has a role as a polar aprotic solvent and a bacterial metabolite.
Methyl Ethyl Ketone is a dialkyl ketone, a methyl ketone, a volatile organic compound and a butanone.


Methyl Ethyl Ketone is a natural product found in Aloe africana, Psidium guajava, and other organisms with data available.
Methyl Ethyl Ketone occurs as a natural product.
Methyl Ethyl Ketone is made by some trees and found in some fruits and vegetables in small amounts.


Methyl Ethyl Ketone is also released to the air from car and truck exhausts.
Methyl Ethyl Ketone is an organic compound with the formula CH3C(O)CH2CH3.
This colourless liquid ketone, Methyl Ethyl Ketone, has a sharp, sweet odor reminiscent of acetone.


Methyl Ethyl Ketone is produced industrially on a large scale, but occurs in nature only in trace amounts.
Methyl Ethyl Ketone is partially soluble in water, and is commonly used as an industrial solvent.
Methyl Ethyl Ketone is an isomer of another solvent, tetrahydrofuran.
Methyl Ethyl Ketone (C4H8O or CH3CH3COCH2CH3) is a colorless, flammable liquid with a sharp odor.



USES and APPLICATIONS of METHYL ETHYL KETONE:
Methyl Ethyl Ketone is a liquid solvent used in surface coatings, adhesives, printing inks, chemical intermediates, magnetic tapes, and as dewaxing agents in lubricant base oil production.
Methyl Ethyl Ketone also is used as a solvent for fats, oils, waxes and resins.


Methyl Ethyl Ketone is a highly efficient and versatile solvent for surface coatings.
Because of its effectiveness as a solvent, Methyl Ethyl Ketone is especially valuable in formulating high solids coatings, which help to reduce emissions from coating operations.


Methyl Ethyl Ketone is the ideal choice for Epoxy thinning and cleanup.
Methyl Ethyl Ketone is soluble in water and is commonly used as an industrial solvent.
Methyl Ethyl Ketone is used in processes involving varnishes, paint remover, a denaturing agent for denatured alcohol, glues, and as a cleaning agent.


Methyl Ethyl Ketone has similar solvent properties to acetone but boils at a higher temperature and has a significantly slower evaporation rate
With a high flashpoint and quick evaporation Methyl Ethyl Ketone is commonly used as a paint thinner, industrial solvent, in surface coatings, varnishes, as a paint remover and cleaning for automotive, mechanical and marine industries.


Methyl Ethyl Ketone is used as a solvent, as a plastic welding agent and as a precursor to methyl ethyl ketone peroxide.
Methyl ethyl ketone is used as a solvent for lacquers, adhesives, cleaning materials to be electroplated, degreasing, rubber and rubber cement, printing inks, and paints, wood stains and varnishes, paint removers, in cleaning solutions, as a catalyst, and as a carrier.


Methyl Ethyl Ketone is used as a solvent for paint, lube-oil dewaxing, adhesive and printing ink, Raw material for organic syntheses.
Methyl Ethyl Ketone is used as a solvent in synthetic resins manufacturing and in the surface-coating industry.
Methyl ethyl ketone is used as a plastic welding agent because it has the ability to dissolve polystyrene and various other plastics.


Methyl Ethyl Ketone is used in the production of varnishes, and paraffin wax.
Methyl Ethyl Ketone acts as a precursor in polymerization reactions.
Methyl Ethyl Ketone is used as a cleaning agent.


Methyl ethyl ketone is used in glues.
Methyl Ethyl Ketone is used in the production of petroleum.
Methyl Ethyl Ketone is used in organic synthesis reactions.


Methyl Ethyl Ketone is used in the sectors of paint, coating and detergent.
Methyl Ethyl Ketone is found in paints, glues and finishes because it quickly evaporates in air and will dissolve in many substances.
Methyl Ethyl Ketone is a powerful solvent that is widely used in the chemical and manufacturing industries.


Its ability to dissolve a wide range of substances makes Methyl Ethyl Ketone a valuable tool for the production of plastics, resins, and synthetic fibers.
Methyl Ethyl Ketone is also used in the paint and coatings industry, as well as in printing and graphic arts.
In addition to its versatility, Methyl Ethyl Ketone is known for its fast-drying properties and ability to remove tough stains and residues.


This makes Methyl Ethyl Ketone an excellent choice for cleaning and degreasing applications.
Overall, Methyl Ethyl Ketone is a reliable and efficient solvent that can greatly improve productivity in various industries.
Its versatility and fast-drying properties make Methyl Ethyl Ketone a valuable choice for a variety of applications.


Methyl Ethyl Ketone is also an intermediate in preparing pharmaceuticals, dyes, detergents, fragrances, antioxidants, and specific catalysts.
Methyl Ethyl Ketone is produced industrially in large quantities and is mainly used as a solvent, often found in mixtures with acetone, ethyl acetate, n-hexane or alcohols.


Methyl Ethyl Ketone has applications in the surface coating industry such as in paints, plastics, adhesives and printing inks.
Other uses of Methyl Ethyl Ketone include the manufacture of colourless synthetic resins and leather treatment products, rubbers, lacquers, varnishes, glues and sealants.


The primary use of Methyl Ethyl Ketone is as a solvent in processes involving gums, resins, cellulose acetate, and cellulose nitrate.
Methyl Ethyl Ketone is also used in the synthetic rubber industry, in the production of paraffin wax, and in household products such as lacquer and varnishes, paint remover, and glues.


Methyl Ethyl Ketone is used as a solvent for resins, coatings, inks, a binder for dyes, a lubricating oil dewaxing agent, a vulcanization accelerator, etc.
Methyl Ethyl Ketone is compatible with high-solids formulations, polyurethane, polyester, acrylic, and cellulose.
Methyl Ethyl Ketone is used in polychloroprene adhesives applications.


Methyl Ethyl Ketone is a specialty thinner for epoxies, lacquers and adhesives, as well as polyester resins used in fiberglass repairs.
Methyl Ethyl Ketone's a fast evaporating and extremely flammable solvent, so it should be handled with care.
Methyl Ethyl Ketone is slower drying than acetone and can also be used as an effective remover for ink, adhesives and contact cement.


Methyl Ethyl Ketone is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Methyl Ethyl Ketone is used in the following products: lubricants and greases, adhesives and sealants, coating products, anti-freeze products, polishes and waxes and fuels.


Other release to the environment of Methyl Ethyl Ketonee is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use as processing aid, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Other release to the environment of Methyl Ethyl Ketone is likely to occur from: outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).
Methyl Ethyl Ketone can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones).


Methyl Ethyl Ketone is used in the following products: coating products, washing & cleaning products, pH regulators and water treatment products, laboratory chemicals and lubricants and greases.
Methyl Ethyl Ketone is used in the following products: photo-chemicals, coating products, laboratory chemicals, polymers and lubricants and greases.


Other release to the environment of Methyl Ethyl Ketone is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Release to the environment of Methyl Ethyl Ketone can occur from industrial use: formulation of mixtures, formulation in materials, in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release, manufacturing of the substance and in the production of articles.


Methyl Ethyl Ketone is used in the following products: coating products, inks and toners, laboratory chemicals, pH regulators and water treatment products, lubricants and greases and washing & cleaning products.
Methyl Ethyl Ketone is used for the manufacture of: chemicals


Release to the environment of Methyl Ethyl Ketone can occur from industrial use: in processing aids at industrial sites, of substances in closed systems with minimal release, formulation of mixtures, manufacturing of the substance and as an intermediate step in further manufacturing of another substance (use of intermediates).


Release to the environment of Methyl Ethyl Ketone can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), formulation of mixtures, formulation in materials, in the production of articles and of substances in closed systems with minimal release.


Nearly half of its use is in paints and other coatings because it will quickly evaporate into the air and it dissolves many substances.
Methyl Ethyl Ketone is also used in glues and as a cleaning agent.
Methyl Ethyl Ketone occurs as a natural product.


Methyl Ethyl Ketone is made by some trees and found in some fruits and vegetables in small amounts.
Methyl Ethyl Ketone is also released to the air from car and truck exhausts.
Methyl Ethyl Ketone is used as a solvent, for making other chemicals, and for production of wax from petroleum.


Methyl Ethyl Ketone is used in many industries.
Methyl Ethyl Ketone is used as a solvent and in the manufacture of synthetic rubber, paraffin wax, and to make other chemical products.


-Industrial & DIY Uses of Methyl Ethyl Ketone:
Used as a thinner in paint products.
Can be used as a parts cleaner.
Removing paints.
Solvent used for fats, oils, waxes and resins. It is a highly efficient and versatile solvent for surface coatings.
Ideal for automotive parts, marine and paint sundry departments.


-As a solvent:
Methyl Ethyl Ketone is an effective and common solvent and is used in processes involving gums, resins, cellulose acetate and nitrocellulose coatings and in vinyl films.
For this reason Methyl Ethyl Ketone finds use in the manufacture of plastics, textiles, in the production of paraffin wax, and in household products such as lacquer, varnishes, paint remover, a denaturing agent for denatured alcohol, glues, and as a cleaning agent.
Methyl Ethyl Ketone has similar solvent properties to acetone but boils at a higher temperature and has a significantly slower evaporation rate.
Unlike acetone, Methyl Ethyl Ketone forms an azeotrope with water, making it useful for azeotropic distillation of moisture in certain applications.
Methyl Ethyl Ketone is also used in dry erase markers as the solvent of the erasable dye.


-As a plastic welding agent:
As Methyl Ethyl Ketone dissolves polystyrene and many other plastics, it is sold as "model cement" for use in connecting parts of scale model kits.
Though often considered an adhesive, Methyl Ethyl Ketone is functioning as a welding agent in this context.


-Other uses of Methyl Ethyl Ketone:
Methyl Ethyl Ketone is the precursor to methyl ethyl ketone peroxide, which is a catalyst for some polymerization reactions such as crosslinking of unsaturated polyester resins.
Dimethylglyoxime can be prepared from Methyl Ethyl Ketone first by reaction with ethyl nitrite to give diacetyl monoxime followed by conversion to the dioxime:
In the peroxide process on producing hydrazine, the starting chemical ammonia is bonded to Methyl Ethyl Ketone, oxidized by hydrogen peroxide, bonded to another ammonia molecule.
In the final step of the process, hydrolysis produces the desired product, hydrazine, and regenerates the Methyl Ethyl Ketone.
Me(Et)C=NN=C(Et)Me + 2 H2O → 2 Me(Et)C=O + N2H4



CHEMICAL PROPERTIES OF METHYL ETHYL KETONE:
Methyl ethyl ketone is a flammable liquid.
Methyl Ethyl Ketone is partially soluble in water, and soluble in most other organic solvents.
Methyl Ethyl Ketone will float on water while it rapidly dissolves in it.



BENEFITS OF METHYL ETHYL KETONE:
*Solvency power:
For solutions of coating, adhesive and ink resins (polyurethane, polyester, acrylic, cellulose, polychloroprene), and for paint stripper formulations
*Fast evaporation:
For thinners and industrial paint formulations, adhesives and extraction processes
*Low viscosity:
Enabling high-solids formulations in coatings and adhesives



PRODUCTION OF METHYL ETHYL KETONE:
Methyl Ethyl Ketone may be produced by oxidation of 2-butanol.
The dehydrogenation of 2-butanol is catalysed by copper, zinc, or bronze:

CH3CH(OH)CH2CH3 → CH3C(O)CH2CH3 + H2
This is used to produce approximately 700 million kilograms yearly.
Other syntheses that have been examined but not implemented include Wacker oxidation of 2-butene and oxidation of isobutylbenzene, which is analogous to the industrial production of acetone.

The cumene process can be modified to produce phenol and a mixture of acetone and butanone instead of only phenol and acetone in the original.
Both liquid-phase oxidation of heavy naphtha and the Fischer–Tropsch reaction produce mixed oxygenate streams, from which 2-butanone is extracted by fractionation.



PROPERTIES OF METHYL ETHYL KETONE:
*Methyl Ethyl Ketone is a colourless, volatile liquid and has a pleasant pungent smell.
*The flashpoint of Methyl ethyl ketone is 20°F.
*The vapours formed are heavier than air.
*Methyl Ethyl Ketone dissolves in water.
*Methyl Ethyl Ketone is obtained as a natural product.
*Methyl Ethyl Ketone is present in some vegetables and fruits in small quantities.
*Also, Methyl Ethyl Ketone is released from truck and car exhausts.



EXAMPLES OF WORK AND PROCESSES INVOLVING METHYL ETHYL KETONE INCLUDE:
*as a solvent in the application of protective coatings and adhesives
*magnetic tape production
*dewaxing of lubricating oils
*extraction solvent in food processing
*making varnishes and glues
*making synthetic rubber
*making paraffin wax
*industrial and automotive paint
*leather cleaning
*laboratory work
*making cleaning agents
*making explosives and smokeless gun powders.



PRODUCTION OF METHYL ETHYL KETONE:
Methyl ethyl ketone can be obtained by oxidising 2-butanol.
Dehydrogenation of 2-butanol in the presence of a catalyst such as copper, bronze, or zinc.



OCCURRENCE AND USE OF METHYL ETHYL KETONE:
Solvent, denaturing agent, cleaning agent; component of paints, lacquers, varnishes, glues, resins; production of plastics, textiles, paraffin wax; component of automobile and tobacco smoke



HOW METHYL ETHYL KETONE GETS INTO THE ENVIRONMENT:
Methyl ethyl ketone is produced naturally at low levels by many living things.
Human activities can also lead to the release of methyl ethyl ketone into the environment.
Methyl Ethyl Ketone can enter the environment during its production, transport and use.
Methyl Ethyl Ketone may also be released from vehicle exhausts and during the breakdown of other chemicals.
On entering the environment methyl ethyl ketone is rapidly broken down therefore it does not build up in the environment.



EXPOSURE TO METHYL ETHYL KETONE:
Methyl Ethyl Ketone can be found in various food items including meat, fruit and vegetables.
Methyl Ethyl Ketone is a permitted food flavouring substance.
The level of exposure to Methyl Ethyl Ketone anticipated as part of a normal diet is not a concern for health.
The general public may also be exposed to low levels of methyl ethyl ketone in the environment and from cigarette smoke.
People may be exposed to small amounts due to Methyl Ethyl Ketone's use in household products such as paints, varnishes, anti-freeze, cosmetics and perfumes.



PHYSICAL and CHEMICAL PROPERTIES of METHYL ETHYL KETONE:
Molecular Weight: 72.11 g/mol
XLogP3: 0.3
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 1
Exact Mass: 72.057514874 g/mol
Monoisotopic Mass: 72.057514874 g/mol
Topological Polar Surface Area: 17.1Ų
Heavy Atom Count: 5
Formal Charge: 0
Complexity: 38.9
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1

Compound Is Canonicalized: Yes
Chemical formula: C4H8O
Molar mass: 72.107 g·mol−1
Appearance: Colorless liquid
Odor: Mint or acetone-like
Density: 0.8050 g/mL
Melting point: −86 °C (−123 °F; 187 K)
Boiling point: 79.64 °C (175.35 °F; 352.79 K)
Solubility in water: 27.5 g/100 mL
log P: 0.37
Vapor pressure: 78 mmHg (20 °C)
Acidity (pKa): 14.7
Magnetic susceptibility (χ): −45.58·10−6 cm3/mol
Refractive index (nD): 1.37880
Viscosity: 0.43 cP
CAS number: 78-93-3
EC index number: 606-002-00-3
EC number: 201-159-0

Hill Formula: C₄H₈O
Chemical formula: CH₃COC₂H₅
Molar Mass: 72.11 g/mol
HS Code: 2914 12 00
Boiling point: 79.6 °C (1013 hPa)
Density: 0.805 g/cm3 (20 °C)
Explosion limit: 1.8 - 11.5 %(V)
Flash point: -1 °C
Ignition temperature: 514 °C
Melting Point: -87 °C
Vapor pressure: 95 hPa (20 °C)
Solubility: 292 g/l
Physical state: liquid, clear
Color: colorless
Odor: No data available
Melting point/freezing point:
Melting point: -87 °C
Initial boiling point and boiling range: 80 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:

Upper explosion limit: 10,1 %(V)
Lower explosion limit: 1,8 %(V)
Flash point: -3 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: soluble
Partition coefficient: n-octanol/water:
log Pow: 0,3 at 40 °C
Vapor pressure: 95 hPa at 20 °C
Density: 0,805 g/mL at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available

Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Surface tension: 24,6 mN/m at 20 °C
Relative vapor density: 2,49 - (Air = 1.0)
Molecular Formula:C4H8O or CH3COCH2CH3
CAS:78-93-3
UN:1193
Appearance: colorless liquid with acetone-like odor.
Density:0.8 g/cm³
Boiling Point: 79.64 °C
Melting Point: −86 °C
Flash Point: -9 ºC
Molecular weight: 72.11
Boiling point: 79.64°C
Vapor pressure: 74 Torr at 20°C
Freezing point: -86.69°C
Refractive index: 1.3788 at 20°C

Density: 0.8049 g/mL (6.717 lb/gal) at 20°C
0.7997 g/mL (6.673 lb/gal) at 25°C
Dielectric constant: 18.51 at 20°C
Dipole moment: 2.76 D at 25°C
Solvent group: 6
Polarity index (P'): 4.7
Eluotropic value on alumina: 0.51
Viscosity: 0.43 cP at 20°C
Surface tension: 24.0 dyn/cm at 25°C
Solubility in water: 24.0% at 20°C
Solubility of water in methyl ethyl ketone: 10.0% at 20°C
Molecular Weight: 72.10
Boiling Point: ℃ 79.6
Melting Point: ℃ -87.3
Specific Gravity at 20/4℃: 0.8047
Refractive index (): 1.3787
Interfacial Tension (20℃): N/cm 246×10-6
Latent Heat of Evaporation: J/g 443.7

Specific Heat at 20℃: J/g・℃ 2.09
Critical Temperature: ℃ 260
Critical Pressure: MPa 4.39
Water Azeotrope Boiling Point (0.1MPa): ℃ 73.41
Content of azeotrope: wt% MEK 88.7
Coefficient of Expansion (20℃): 0.0013
Flash Point (Tag closed cup tester): ℃ -7.2
Combastion Point: ℃ 514
Explosive Limits in Air vol%: 1.7~11.4
Appearance: Clear and Colorless
Water %: 1.0 MAX.
Free Acid as Acetic Acid: %0.003 MAX.0.0005
Nonvolatile Matter: % 0.003 MAX.0.001
Specific Gravity at 20/20℃: 0.805~0.807 0.8062
Color: Hazen Unit 20 MAX. -
Composition(MEK purity) %99.9

Boiling point: 175°F
Molecular weight: 72.1
Freezing point/melting point: -123°F
Vapor pressure: 78 mmHg
Flash point: 16°F
Vapor density: 2.42
Specific gravity: 0.81
Ionization potential: 9.54 eV
Lower explosive limit (LEL): 1.4% at 200°F
Upper explosive limit (UEL): 11.4% at 200°F
NFPA health rating: 1
NFPA fire rating: 3
NFPA reactivity rating: 0
Melting Point: -86.3°C
Boiling Point: 79.6°C
Vapour Density: 2.5
Specific Gravity: 0.805
Flashpoint: -6°C

Appearance: colorless clear liquid (est)
Assay: 99.50 to 100.00
Food Chemicals Codex Listed: Yes
Specific Gravity: 0.80100 to 0.80300 @ 25.00 °C.
Pounds per Gallon - (est).: 6.665 to 6.682
Refractive Index: 1.37700 to 1.38000 @ 20.00 °C.
Melting Point: -85.00 to -87.00 °C. @ 760.00 mm Hg
Boiling Point: 78.60 to 80.00 °C. @ 760.00 mm Hg
Acid Value: 2.00 max. KOH/g
Vapor Pressure: 90.600000 mmHg @ 25.00 °C.
Vapor Density: 2.49 ( Air = 1 )
Flash Point: 26.00 °F. TCC ( -3.33 °C. )
logP (o/w): 0.290
Soluble in: alcohol, fixed oils
water, 2.23E+05 mg/L @ 25 °C (exp)



FIRST AID MEASURES of METHYL ETHYL KETONE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of METHYL ETHYL KETONE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of METHYL ETHYL KETONE:
-Extinguishing media:
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of METHYL ETHYL KETONE:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Handle with gloves.
Wash and dry hands.
Splash contact:
Material: butyl-rubber
Minimum layer thickness: 0,3 mm
Break through time: 292 min
*Body Protection:
Flame retardant antistatic protective clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of METHYL ETHYL KETONE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Advice on protection against fire and explosion:
Take precautionary measures against static discharge.
*Hygiene measures:
Change contaminated clothing.
Preventive skin protection recommended.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store under inert gas.
Keep container tightly closed in a dry and well-ventilated place.
Hygroscopic.
Store under nitrogen.



STABILITY and REACTIVITY of METHYL ETHYL KETONE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available



SYNONYMS:
2-Butanone
METHYL ETHYL KETONE
Butan-2-one
Butanone
78-93-3
Ethyl methyl ketone
Methylethyl ketone
Meetco
Methyl acetone
Methylethylketone
3-Butanone
Ethylmethylketon
ethylmethylketone
Aethylmethylketon
Butanone 2
Acetone, methyl-
Ethyl methyl cetone
Metiletilchetone
Metyloetyloketon
Ketone, ethyl methyl
MEK
ethylmethyl ketone
Metyl ethyl ketone
methylacetone
Metiletilcetona
Oxobutane
RCRA waste number U159
Methylethylketon
Caswell No. 569
Ethylmethylcetone
2-butanon
FEMA No. 2170
methyl(ethyl) ketone
HSDB 99
UNII-6PT9KLV9IO
6PT9KLV9IO
2-Oxobutane
C2H5COCH3
methyl ethylketone
AI3-07540 (USDA)
EINECS 201-159-0
methyl ethyl cetone
EPA Pesticide Chemical Code 044103
ethyl(methyl) ketone
DTXSID3021516
CHEBI:28398
AI3-07540
MFCD00011648
UN1193
2-Butanone, HPLC Grade
2-BUTANONE-D8
methyl ethyl ketone (mek)
RCRA waste no. U159
DTXCID801516
EC 201-159-0
METHYL ETHYL KETONE (II)
METHYL ETHYL KETONE [II]
Butanon
METHYL ETHYL KETONE (MART.)
METHYL ETHYL KETONE [MART.]
2-Butanone, ACS reagent, >=99.0%
methyl-ethyl ketone
VOC Mixture 249 500 microg/mL in Triacetin
Butanon
Ethylmethylketon
Methylethylketon
MEK
Ketones Mix 5000 microg/mL in MeOH:Water 9:1
n-butanone
EPA VOC Additional Compounds Mixture 2000 microg/mL in Methanol
2-butanona
2-butanal
ethyl methylketone
ethylmathyl ketone
methyl-ethylketone
methylethyl-ketone
butane-2-one
2 -butanone
2- butanone
butan-3-one
methyl etyl ketone
ethyl-methyl ketone
methyl-ethyl-ketone
Ethyl, methyl ketone
Ketone, methyl ethyl
Caswell No 569
MEK (CHRIS Code)
2-Butanone, ACS grade
Butanon (Metyletylketon)
Metyletylketon (Butanon)
MEK [INCI]
2-BUTANONE [FCC]
2-BUTANONE [FHFI]
Pesticide Code: 044103
ghl.PD_Mitscher_leg0.417
CHEMBL15849
2-Butanone, analytical standard
2-Butanone, LR, >=99%
METHYL ETHYL KETONE [MI]
Methyl ethyl ketone, ACS reagent
2-Butanone (Methyl ethyl ketone)
Methyl ethyl ketone (2-Butanone)
METHYL ETHYL KETONE [HSDB]
2-Butanone, AR, >=99.5%
Butan-2-one (methyl ethyl ketone)
METHYL ETHYL KETONE [VANDF]
2-Butanone, technical grade, 99%
Tox21_200041
LMFA12000043
NA1193
STL146562
2-Butanone, natural, >=99%, FG
METHYL ETHYL KETONE [USP-RS]
AKOS000118991
2-Butanone, for HPLC, >=99.7%
LS-1761
UN 1193
2-Butanone, puriss., >=99% (GC)
2-Butanone, ReagentPlus(R), >=99%
CAS-78-93-3
2-Butanone, >=99.5%, FCC, FG
NCGC00090973-01
NCGC00090973-02
NCGC00257595-01
BP-30009
2-Butanone 100 microg/mL in Acetonitrile
Ethyl methyl ketone or methyl ethyl ketone
2-Butanone, SAJ first grade, >=99.0%
2-Butanone, JIS special grade, >=99.0%
Butanone, 2-
(Methyl ethyl ketone; MEK)
E0140
FT-0628728
Methyl ethyl ketone (MEK)
2-Butanone
2-Butanone (or Methyl Ethyl Ketone or MEK)
Butanone, 2-
(Methyl ethyl ketone; MEK)
C02845
2-Butanone, HPLC grade, for HPLC, >=99.5%
A839534
ETHYL METHYL KETONE (METHYL ETHYL KETONE)
Q372291
InChI=1/C4H8O/c1-3-4(2)5/h3H2,1-2H
Ketones Mixture 64 10000 microg/mL in Dimethyl Formamide
2-Butanone, puriss., ACS reagent, reag. Ph. Eur., 99.5%
DB 44/814-2010 SVOC Mixture 494 2000 microg/mL in Methanol
GB/T 10004-2008 VOC Mixture 574 2000 microg/mL in Methanol
2-Butanone, 5000 mug/mL in methanol: water (9:1), analytical standard
2-Butanone, puriss. p.a., ACS reagent, reag. Ph. Eur., >=99.5% (GC)
Ethyl methyl ketone or methyl ethyl ketone [UN1193]
Ethyl methyl ketone or methyl ethyl ketone [UN1193]
Methyl ethyl ketone, United States Pharmacopeia (USP) Reference Standard
EPA Method 8015 Non-halogenated VOC Mixture 410 200 microg/mL in Methanol
EPA Method 8015 Non-halogenated VOC Mixture 411 2000 microg/mL in Methanol
HJ 1153-2020 Aldehyde and Ketones Mixture 344 1000 microg/mL in Acetonitrile
Ketones Mixture Maximum Difference from Nom.:1.5% 5000 microg/mL in Methanol:Water 9:1
Methyl Ethyl Ketone, Pharmaceutical Secondary Standard
Butan-2-one
2-Butanone
Ethyl methyl ketone
Ethylmethylketone
Methyl ethyl ketone
Methylpropanone
Methylacetone
2-Butanone
Ethyl methyl ketone
Ethylmethylketone
Methyl ethyl ketone (MEK)
ethyl methyl ketone
MEK
methyl acetone
methyl ethyl ketone
Butanone
Methyl ethyl ketone
MEK
2-Butanone
Methylpropanone
Ethylmethylketone
Methylacetone
2-butanone
2-oxobutane
3-butanone
acetone, methyl-
AI3-07540
butan-2-one
butanone
Caswell NO 569
ethyl methyl ketone
Ethyl methyl ketone (methyl ethyl ketone)
EXXON methylethyl ketone
FEMA N°. 2170
ketone, ethyl methyl-
meetco
MEK (= methyl ethyl ketone)
methyl 2-propanone
methyl acetone
Butanone; 2-butanone
3-butanone
Caswell No. 569
Meetco
MEK
Methyl acetone
AI3-07540
2-oxobutane
EPA Pesticide Code: 044103


METHYL ETHYL KETONE
METHYL ETHYL KETONE Methyl ethyl ketone Jump to navigationJump to search MEK[1] Skeletal formula of Methyl ethyl ketone Ball-and-stick model of Methyl ethyl ketone Space-filling model of Methyl ethyl ketone methyl ethyl ketone Names Preferred IUPAC name Butan-2-one[2] Other names 2-Methyl ethyl ketone Ethyl methyl ketone[2] Ethylmethylketone Methyl ethyl ketone (MEK; deprecated[2]) Methylpropanone Methylacetone Identifiers CAS Number 78-93-3 check 3D model (JSmol) Interactive image Interactive image Beilstein Reference 741880 ChEBI CHEBI:28398 check ChEMBL ChEMBL15849 check ChemSpider 6321 check ECHA InfoCard 100.001.054 Edit this at Wikidata Gmelin Reference 25656 KEGG C02845 check PubChem CID 6569 RTECS number EL6475000 UNII 6PT9KLV9IO check CompTox Dashboard (EPA) DTXSID3021516 Edit this at Wikidata InChI[show] SMILES[show] Properties Chemical formula C4H8O Molar mass 72.107 g·mol−1 Appearance Colorless liquid Odor Mint or acetone-like[3] Density 0.8050 g/mL Melting point −86 °C (−123 °F; 187 K) Boiling point 79.64 °C (175.35 °F; 352.79 K) Solubility in water 27.5 g/100 mL log P 0.37[4] Vapor pressure 78 mmHg (20 °C)[3] Acidity (pKa) 14.7 Magnetic susceptibility (χ) −45.58·10−6 cm3/mol Refractive index (nD) 1.37880 Viscosity 0.43 cP Structure Dipole moment 2.76 D Hazards Safety data sheet See: data page Safety Data Sheet GHS pictograms GHS02: FlammableGHS07: Harmful[5] GHS Signal word Danger[5] GHS hazard statements H225, H319, H336[5] GHS precautionary statements P233, P210, P280, P240, P241, P243, P242, P264, P261, P271, P370+378, P303+361+353, P305+351+338, P337+313, P304+340, P312, P403+235, P501, P403+233, P405[5] NFPA 704 (fire diamond) NFPA 704 four-colored diamond 310 Flash point −9 °C (16 °F; 264 K) Autoignition temperature 505 °C (941 °F; 778 K) Explosive limits 1.4–11.4%[3] Lethal dose or concentration (LD, LC): LD50 (median dose) 2737 mg/kg (oral, rat) 4050 mg/kg (oral, mouse)[6] LC50 (median concentration) 12667 ppm (mammal) 13333 ppm (mouse, 2 hr) 7833 ppm (rat, 8 hr)[6] NIOSH (US health exposure limits): PEL (Permissible) TWA 200 ppm (590 mg/m3)[3] REL (Recommended) TWA 200 ppm (590 mg/m3) ST 300 ppm (885 mg/m3)[3] IDLH (Immediate danger) 3000 ppm[3] Related compounds Related ketones Acetone; 3-pentanone; 3-methylMethyl ethyl ketone Supplementary data page Structure and properties Refractive index (n), Dielectric constant (εr), etc. Thermodynamic data Phase behaviour solid–liquid–gas Spectral data UV, IR, NMR, MS Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). check verify (what is check☒ ?) Infobox references Methyl ethyl ketone, also known as methyl ethyl ketone (MEK),[a] is an organic compound with the formula CH3C(O)CH2CH3. This colourless liquid ketone has a sharp, sweet odor reminiscent of acetone. It is produced industrially on a large scale, but occurs in nature only in trace amounts.[7] It is partially soluble in water, and is commonly used as an industrial solvent.[8] It is an isomer of another solvent, tetrahydrofuran. Contents 1 Production 2 Applications 2.1 As a solvent 2.2 As a plastic welding agent 2.3 Other uses 3 Safety 3.1 Flammability 3.2 Health effects 3.3 Regulation 4 See also 5 Notes 6 References 7 External links Production Methyl ethyl ketone may be produced by oxidation of 2-butanol. The dehydrogenation of 2-butanol using a catalyst is catalyzed by copper, zinc, or bronze: CH3CH(OH)CH2CH3 → CH3C(O)CH2CH3 + H2 This is used to produce approximately 700 million kilograms yearly. Other syntheses that have been examined but not implemented include Wacker oxidation of 2-butene and oxidation of isobutylbenzene, which is analogous to the industrial production of acetone.[7] The cumene process can be modified to produce phenol and a mixture of acetone and Methyl ethyl ketone instead of only phenol and acetone in the original.[9] Both liquid-phase oxidation of heavy naphtha and the Fischer-Tropsch reaction produce mixed oxygenate streams, from which 2-Methyl ethyl ketone is extracted by fractionation.[10] Applications As a solvent Methyl ethyl ketone is an effective and common solvent[8] and is used in processes involving gums, resins, cellulose acetate and nitrocellulose coatings and in vinyl films.[11] For this reason it finds use in the manufacture of plastics, textiles, in the production of paraffin wax, and in household products such as lacquer, varnishes, paint remover, a denaturing agent for denatured alcohol, glues, and as a cleaning agent. It has similar solvent properties to acetone but boils at a higher temperature and has a significantly slower evaporation rate.[12] Unlike acetone, it forms an azeotrope with water,[13][14] making it useful for azeotropic distillation of moisture in certain applications. Methyl ethyl ketone is also used in dry erase markers as the solvent of the erasable dye. As a plastic welding agent As Methyl ethyl ketone dissolves polystyrene and many other plastics, it is sold as "model cement" for use in connecting parts of scale model kits. Though often considered an adhesive, it is actually functioning as a welding agent in this context. Other uses Methyl ethyl ketone is the precursor to methyl ethyl ketone peroxide, which is a catalyst for some polymerization reactions such as crosslinking of unsaturated polyester resins. Dimethylglyoxime can be prepared from Methyl ethyl ketone first by reaction with ethyl nitrite to give diacetyl monoxime followed by conversion to the dioxime:[15] Preparation of dimethylglyoxime.png In the Peroxide process on producing hydrazine, the starting chemical ammonia is bonded to Methyl ethyl ketone, oxidized by hydrogen peroxide, bonded to another ammonia molecule. Pechiney-Ugine-Kuhlmann process.png In the final step of the process, a hydrolysis produces the desired product hydrazine and regenerates the Methyl ethyl ketone. Me(Et)C=NN=C(Et)Me + 2 H2O → 2 Me(Et)C=O + N2H4 Safety Flammability Methyl ethyl ketone can react with most oxidizing materials, and can produce fires.[8] It is moderately explosive, requiring only a small flame or spark to cause a vigorous reaction.[8] Methyl ethyl ketone fires should be extinguished with carbon dioxide, dry agents, or alcohol-resistant foam.[8] Concentrations in the air high enough to be flammable are intolerable to humans due to the irritating nature of the vapor.[12] Health effects Methyl ethyl ketone is a constituent of tobacco smoke.[16] It is an irritant, causing irritation to the eyes and nose of humans.[12] Serious health effects in animals have been seen only at very high levels. These included skeletal birth defects and low birth weight in mice, when they inhaled it at the highest dose tested (3000 ppm for 7 hours/day).[17] There are no long-term studies with animals breathing or drinking it,[18] and no studies for carcinogenicity in animals breathing or drinking it.[19]:96 There is some evidence that Methyl ethyl ketone can potentiate the toxicity of other solvents, in contrast to the calculation of mixed solvent exposures by simple addition of exposures.[20] As of 2010, some reviewers advised caution in using Methyl ethyl ketone because of reports of neuropsychological effects.[21] Methyl ethyl ketone is listed as a Table II precursor under the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances.[22] Regulation Emission of Methyl ethyl ketone was regulated in the US as a hazardous air pollutant, because it is a volatile organic compound contributing to the formation of tropospheric (ground-level) ozone. In 2005, the US Environmental Protection Agency removed Methyl ethyl ketone from the list of hazardous air pollutants (HAPs).[23][24][25] Methyl Ethyl Ketone (MEK) Physical characteristic: Colorless Liquid Chemical formula: C4H8O Molecular weight: 72,11 g/mol Type of packaging: Barrel / IBC / Tank MEK is an active & organic solvent. It is in a clear, inflammable and liquid form. It is in the ketone groups. It has a high evaporation rate. It is one of the most widely used ketones in the industry. Areas of usage: It is used in organic synthesis reactions. It is used in the sectors of paint, coating and detergent. Methyl Ethyl Ketone is a liquid solvent used in surface coatings, adhesives, printing inks, chemical intermediates, magnetic tapes and lube oil dewaxing agents. Methyl Ethyl Ketone also is used as an extraction medium for fats, oils, waxes and resins. It is a highly efficient and versatile solvent for surface coatings. Because of its effectiveness as a solvent, Methyl Ethyl Ketone is especially valuable in formulating high solids coatings, which help to reduce emissions from coating operations. Methyl Ethyl Ketone is a natural component of many foods, including apple juice, beans, chicken, honey and a variety of cheeses. Synonyms for Methyl Ethyl Ketone are 2-butanone, ethyl methyl ketone, and methyl acetone. Methyl Ethyl Ketone is a Food and Drug Administration (FDA)-approved indirect food additive for adhesives and polymers. The panel, with the U.S. EPA as the sponsoring organization, prepared the technical support documents for Methyl Ethyl Ketone under the International Council of Chemical Associations (ICCA) Voluntary High Production Volume (HPV) chemical review. Methyl Ethyl Ketone Hazardous Air Pollutant Delisting On December 19, 2005, EPA issued a final rule removing Methyl Ethyl Ketone from Section 112 (b) (1) of the Clean Air Act. Petitions to remove a substance from the HAP list are authorized under Section 112 (b) (3). EPA determined that ambient concentrations, bioaccumulation, or deposition of Methyl Ethyl Ketone may not reasonably be anticipated to cause adverse human health or environmental effects. The panel's delisting petition presented extensive information on Methyl Ethyl Ketone's potential health and environmental effects, environmental releases, and resulting ambient air concentrations. Hazard information included in the petition illustrated Methyl Ethyl Ketone’s low acute and chronic toxicity and low environmental toxicity. Air dispersion modeling results showed that ambient concentrations of Methyl Ethyl Ketone, even at the highest fenceline levels are below levels of concern. Methyl Ethyl Ketone EPCRA Section 313 Delisting On June 30, 2005, EPA deleted Methyl Ethyl Ketone from its list of chemicals subject to reporting under Section 313 of the Emergency Planning and Community Right-to Know Act’s Toxic Release Inventory (TRI) and Section 6607 of the Pollution Prevention Act of 1990. Facilities are no longer required to report releases of and other waste management information on Methyl Ethyl Ketone. EPA’s final delisting rule is the result of a decision by the Court of Appeals of the District of Columbia Circuit, on an appeal filed by the panel, to overturn the District Court and direct EPA to delist Methyl Ethyl Ketone from the TRI. Methyl Ethyl Ketone VCCEP Independent Review On February 19, 2004, the panel participated in an independent review, coordinated by Toxicology Excellence for Risk Assessment (TERA), of Methyl Ethyl Ketone under EPA’s Voluntary Children’s Chemical Evaluation Program (VCCEP). The purpose of the review was to determine whether existing data are adequate to characterize the risks of Methyl Ethyl Ketone to children, and if not, to identify data needs. The panel’s submission to TERA included a quantitative risk characterization demonstrating that normally anticipated children’s exposures to Methyl Ethyl Ketone pose negligible adverse health risks and that no further data are needed to adequately characterize risk to children under the VCCEP program. On April 19, 2004, TERA issued its report of the Methyl Ethyl Ketone peer consultation meeting. In summary, panel members concluded that the Methyl Ethyl Ketone data were adequate to characterize risks to children as outlined under the VCCEP program. No data needs were identified by any of the review committee members. Methyl ethyl ketone Jump to navigationJump to search MEK[1] Skeletal formula of Methyl ethyl ketone Ball-and-stick model of Methyl ethyl ketone Space-filling model of Methyl ethyl ketone methyl ethyl ketone Names Preferred IUPAC name Butan-2-one[2] Other names 2-Methyl ethyl ketone Ethyl methyl ketone[2] Ethylmethylketone Methyl ethyl ketone (MEK; deprecated[2]) Methylpropanone Methylacetone Identifiers CAS Number 78-93-3 check 3D model (JSmol) Interactive image Interactive image Beilstein Reference 741880 ChEBI CHEBI:28398 check ChEMBL ChEMBL15849 check ChemSpider 6321 check ECHA InfoCard 100.001.054 Edit this at Wikidata Gmelin Reference 25656 KEGG C02845 check PubChem CID 6569 RTECS number EL6475000 UNII 6PT9KLV9IO check CompTox Dashboard (EPA) DTXSID3021516 Edit this at Wikidata InChI[show] SMILES[show] Properties Chemical formula C4H8O Molar mass 72.107 g·mol−1 Appearance Colorless liquid Odor Mint or acetone-like[3] Density 0.8050 g/mL Melting point −86 °C (−123 °F; 187 K) Boiling point 79.64 °C (175.35 °F; 352.79 K) Solubility in water 27.5 g/100 mL log P 0.37[4] Vapor pressure 78 mmHg (20 °C)[3] Acidity (pKa) 14.7 Magnetic susceptibility (χ) −45.58·10−6 cm3/mol Refractive index (nD) 1.37880 Viscosity 0.43 cP Structure Dipole moment 2.76 D Hazards Safety data sheet See: data page Safety Data Sheet GHS pictograms GHS02: FlammableGHS07: Harmful[5] GHS Signal word Danger[5] GHS hazard statements H225, H319, H336[5] GHS precautionary statements P233, P210, P280, P240, P241, P243, P242, P264, P261, P271, P370+378, P303+361+353, P305+351+338, P337+313, P304+340, P312, P403+235, P501, P403+233, P405[5] NFPA 704 (fire diamond) NFPA 704 four-colored diamond 310 Flash point −9 °C (16 °F; 264 K) Autoignition temperature 505 °C (941 °F; 778 K) Explosive limits 1.4–11.4%[3] Lethal dose or concentration (LD, LC): LD50 (median dose) 2737 mg/kg (oral, rat) 4050 mg/kg (oral, mouse)[6] LC50 (median concentration) 12667 ppm (mammal) 13333 ppm (mouse, 2 hr) 7833 ppm (rat, 8 hr)[6] NIOSH (US health exposure limits): PEL (Permissible) TWA 200 ppm (590 mg/m3)[3] REL (Recommended) TWA 200 ppm (590 mg/m3) ST 300 ppm (885 mg/m3)[3] IDLH (Immediate danger) 3000 ppm[3] Related compounds Related ketones Acetone; 3-pentanone; 3-methylMethyl ethyl ketone Supplementary data page Structure and properties Refractive index (n), Dielectric constant (εr), etc. Thermodynamic data Phase behaviour solid–liquid–gas Spectral data UV, IR, NMR, MS Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). check verify (what is check☒ ?) Infobox references Methyl ethyl ketone, also known as methyl ethyl ketone (MEK),[a] is an organic compound with the formula CH3C(O)CH2CH3. This colourless liquid ketone has a sharp, sweet odor reminiscent of acetone. It is produced industrially on a large scale, but occurs in nature only in trace amounts.[7] It is partially soluble in water, and is commonly used as an industrial solvent.[8] It is an isomer of another solvent, tetrahydrofuran. Contents 1 Production 2 Applications 2.1 As a solvent 2.2 As a plastic welding agent 2.3 Other uses 3 Safety 3.1 Flammability 3.2 Health effects 3.3 Regulation 4 See also 5 Notes 6 References 7 External links Production Methyl ethyl ketone may be produced by oxidation of 2-butanol. The dehydrogenation of 2-butanol using a catalyst is catalyzed by copper, zinc, or bronze: CH3CH(OH)CH2CH3 → CH3C(O)CH2CH3 + H2 This is used to produce approximately 700 million kilograms yearly. Other syntheses that have been examined but not implemented include Wacker oxidation of 2-butene and oxidation of isobutylbenzene, which is analogous to the industrial production of acetone.[7] The cumene process can be modified to produce phenol and a mixture of acetone and Methyl ethyl ketone instead of only phenol and acetone in the original.[9] Both liquid-phase oxidation of heavy naphtha and the Fischer-Tropsch reaction produce mixed oxygenate streams, from which 2-Methyl ethyl ketone is extracted by fractionation.[10] Applications As a solvent Methyl ethyl ketone is an effective and common solvent[8] and is used in processes involving gums, resins, cellulose acetate and nitrocellulose coatings and in vinyl films.[11] For this reason it finds use in the manufacture of plastics, textiles, in the production of paraffin wax, and in household products such as lacquer, varnishes, paint remover, a denaturing agent for denatured alcohol, glues, and as a cleaning agent. It has similar solvent properties to acetone but boils at a higher temperature and has a significantly slower evaporation rate.[12] Unlike acetone, it forms an azeotrope with water,[13][14] making it useful for azeotropic distillation of moisture in certain applications. Methyl ethyl ketone is also used in dry erase markers as the solvent of the erasable dye. As a plastic welding agent As Methyl ethyl ketone dissolves polystyrene and many other plastics, it is sold as "model cement" for use in connecting parts of scale model kits. Though often considered an adhesive, it is actually functioning as a welding agent in this context. Other uses Methyl ethyl ketone is the precursor to methyl ethyl ketone peroxide, which is a catalyst for some polymerization reactions such as crosslinking of unsaturated polyester resins. Dimethylglyoxime can be prepared from Methyl ethyl ketone first by reaction with ethyl nitrite to give diacetyl monoxime followed by conversion to the dioxime:[15] Preparation of dimethylglyoxime.png In the Peroxide process on producing hydrazine, the starting chemical ammonia is bonded to Methyl ethyl ketone, oxidized by hydrogen peroxide, bonded to another ammonia molecule. Pechiney-Ugine-Kuhlmann process.png In the final step of the process, a hydrolysis produces the desired product hydrazine and regenerates the Methyl ethyl ketone. Me(Et)C=NN=C(Et)Me + 2 H2O → 2 Me(Et)C=O + N2H4 Safety Flammability Methyl ethyl ketone can react with most oxidizing materials, and can produce fires.[8] It is moderately explosive, requiring only a small flame or spark to cause a vigorous reaction.[8] Methyl ethyl ketone fires should be extinguished with carbon dioxide, dry agents, or alcohol-resistant foam.[8] Concentrations in the air high enough to be flammable are intolerable to humans due to the irritating nature of the vapor.[12] Health effects Methyl ethyl ketone is a constituent of tobacco smoke.[16] It is an irritant, causing irritation to the eyes and nose of humans.[12] Serious health effects in animals have been seen only at very high levels. These included skeletal birth defects and low birth weight in mice, when they inhaled it at the highest dose tested (3000 ppm for 7 hours/day).[17] There are no long-term studies with animals breathing or drinking it,[18] and no studies for carcinogenicity in animals breathing or drinking it.[19]:96 There is some evidence that Methyl ethyl ketone can potentiate the toxicity of other solvents, in contrast to the calculation of mixed solvent exposures by simple addition of exposures.[20] As of 2010, some reviewers advised caution in using Methyl ethyl ketone because of reports of neuropsychological effects.[21] Methyl ethyl ketone is listed as a Table II precursor under the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances.[22] Regulation Emission of Methyl ethyl ketone was regulated in the US as a hazardous air pollutant, because it is a volatile organic compound contributing to the formation of tropospheric (ground-level) ozone. In 2005, the US Environmental Protection Agency removed Methyl ethyl ketone from the list of hazardous air pollutants (HAPs).[23][24][25] Methyl Ethyl Ketone (MEK) Physical characteristic: Colorless Liquid Chemical formula: C4H8O Molecular weight: 72,11 g/mol Type of packaging: Barrel / IBC / Tank MEK is an active & organic solvent. It is in a clear, inflammable and liquid form. It is in the ketone groups. It has a high evaporation rate. It is one of the most widely used ketones in the industry. Areas of usage: It is used in organic synthesis reactions. It is used in the sectors of paint, coating and detergent. Methyl Ethyl Ketone is a liquid solvent used in surface coatings, adhesives, printing inks, chemical intermediates, magnetic tapes and lube oil dewaxing agents. Methyl Ethyl Ketone also is used as an extraction medium for fats, oils, waxes and resins. It is a highly efficient and versatile solvent for surface coatings. Because of its effectiveness as a solvent, Methyl Ethyl Ketone is especially valuable in formulating high solids coatings, which help to reduce emissions from coating operations. Methyl Ethyl Ketone is a natural component of many foods, including apple juice, beans, chicken, honey and a variety of cheeses. Synonyms for Methyl Ethyl Ketone are 2-butanone, ethyl methyl ketone, and methyl acetone. Methyl Ethyl Ketone is a Food and Drug Administration (FDA)-approved indirect food additive for adhesives and polymers. The panel, with the U.S. EPA as the sponsoring organization, prepared the technical support documents for Methyl Ethyl Ketone under the International Council of Chemical Associations (ICCA) Voluntary High Production Volume (HPV) chemical review. Methyl Ethyl Ketone Hazardous Air Pollutant Delisting On December 19, 2005, EPA issued a final rule removing Methyl Ethyl Ketone from Section 112 (b) (1) of the Clean Air Act. Petitions to remove a substance from the HAP list are authorized under Section 112 (b) (3). EPA determined that ambient concentrations, bioaccumulation, or deposition of Methyl Ethyl Ketone may not reasonably be anticipated to cause adverse human health or environmental effects. The panel's delisting petition presented extensive information on Methyl Ethyl Ketone's potential health and environmental effects, environmental releases, and resulting ambient air concentrations. Hazard information included in the petition illustrated Methyl Ethyl Ketone’s low acute and chronic toxicity and low environmental toxicity. Air dispersion modeling results showed that ambient concentrations of Methyl Ethyl Ketone, even at the highest fenceline levels are below levels of concern. Methyl Ethyl Ketone EPCRA Section 313 Delisting On June 30, 2005, EPA deleted Methyl Ethyl Ketone from its list of chemicals subject to reporting under Section 313 of the Emergency Planning and Community Right-to Know Act’s Toxic Release Inventory (TRI) and Section 6607 of the Pollution Prevention Act of 1990. Facilities are no longer required to report releases of and other waste management information on Methyl Ethyl Ketone. EPA’s final delisting rule is the result of a decision by the Court of Appeals of the District of Columbia Circuit, on an appeal filed by the panel, to overturn the District Court and direct EPA to delist Methyl Ethyl Ketone from the TRI. Methyl Ethyl Ketone VCCEP Independent Review On February 19, 2004, the panel participated in an independent review, coordinated by Toxicology Excellence for Risk Assessment (TERA), of Methyl Ethyl Ketone under EPA’s Voluntary Children’s Chemical Evaluation Program (VCCEP). The purpose of the review was to determine whether existing data are adequate to characterize the risks of Methyl Ethyl Ketone to children, and if not, to identify data needs. The panel’s submission to TERA included a quantitative risk characterization demonstrating that normally anticipated children’s exposures to Methyl Ethyl Ketone pose negligible adverse health risks and that no further data are needed to adequately characterize risk to children under the VCCEP program. On April 19, 2004, TERA issued its report of the Methyl Ethyl Ketone peer consultation meeting. In summary, panel members concluded that the Methyl Ethyl Ketone data were adequate to characterize risks to children as outlined under the VCCEP program. No data needs were identified by any of the review committee members.
Methyl Ethyl Ketoxime
Methyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate; Methyl 3,5-bis(tert-butyl)-4-hydroxyhydrocinnamate; 3,5-di-tert-butyl-4-hydroxyhydrocinnamic acid methyl ester; Methyl 3,5-di-tert-butyl-4-hydroxyhydrocinnamate; Methyl 3-(4-hydroxy-3,5-di-tert-butylphenyl)propionate; 3,5-Bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoic acid methyl ester; 3,5-Bis(1,1-dimethylethyl)-4-hydroxyhydrocinnamic acid methyl ester CAS NO:6386-38-5
MÉTHYL ÉTHYLCELLULOSE
METHYL GLUCOSE DIOLEATE, N° CAS : 82933-91-3, Nom INCI : METHYL GLUCOSE DIOLEATE, N° EINECS/ELINCS : 280-069-3. Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau, Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau. Agent d'entretien de la peau : Maintient la peau en bon état. 2,6-Di-O--(9Z)-9-octadecenoyl-α-D-glucopyranoside de méthyle [French] [ACD/IUPAC Name] 280-069-3 [EINECS] 82933-91-3 [RN] Methyl 2,6-di-O--(9Z)-9-octadecenoyl-α-D-glucopyranoside [ACD/IUPAC Name] METHYL D-GLUCOPYRANOSIDE 2,6-DIOLEATE Methyl-2,6-di-O--(9Z)-9-octadecenoyl-α-D-glucopyranosid [German] [ACD/IUPAC Name] α-D-Glucopyranoside, methyl 2,6-bis-O-[(9Z)-1-oxo-9-octadecen-1-yl]- [ACD/Index Name] 106818-54-6 [RN] 122703-32-6 [RN] METHYL GLUCOSE DIOLEATE UNII-FA9KFJ4Z6P
METHYL GLUCETH DOE 120KC
Methyl Gluceth DOE 120KC is a polyethylene glycol ether of the diester of methyl glucose and oleic acid with an average of 120 moles of etylene oxide.
Methyl Gluceth DOE 120KC works as a surfactant cleansing agent.
Methyl Gluceth DOE 120KC is used in hair care products based on surfactants as a thickening and viscosity modifier.

CAS: 86893-19-8
MF: (C2H4O)mult(C2H4O)multC43H78O

Synonyms
PEG 120 METHYL GLUCOSE DIOLEATE;2-ethanediyl),.alpha.-hydro-.omega.-hydroxy-,etherwithmethylD-glucopyranoside2,6-di-9-octadecePoly(oxy-1;2-ethanediyl),alpha-hydro-omega-hydroxy-poly(oxy-etherwithmethyld-glu;6-di-9-octadecenoate(2:1),(z,z)-copyranoside;alpha-hydro-omega-hydroxy-,etherwithmethyld-glucopyranoside2,6-di-9-octadecenoapoly(oxy-2-ethanediyl);Antil 120 Plus;Glucamate DOE-120 Thickener;glucamatedioleate;PEG-120 methyl glucose dioleate;AEC PEG-120 METHYL GLUCOSE DIOLEATE;ANTIL 120 PLUS;GLUCAMATE DOE-120 THICKENER;MACROGOL 120 METHYL GLUCOSE DIOLEATE;PEG 120 methyl glucose dioleate;PEG-120 METHYL GLUCOSE DIOLEATE (II);POLYETHYLENE GLYCOL (120) METHYL GLUCOSE DIOLEATE;YM0K64F20V

Methyl Gluceth DOE 120KC improves the performance and texture of formulations and is perfect for use in infant shampoos, cleansers, conditioners, and antibacterial liquid soaps.
During product development, Methyl Gluceth DOE 120KC is easy to handle thanks to its solid composition.
Acts as a viscosity building agent when used with surfactants.
Methyl Gluceth DOE 120KC has low toxicity profile as it is derived from natural methyl glucoside with 120 moles of ethylene oxide.
Methyl Gluceth DOE 120KC is a non-irritant product.
Reduces stimulation and provides light and smooth feel.
Used in baby shampoos, liquid soaps, shampoos and shower gels.

Methyl Gluceth DOE 120KC is perfect for use in rinse-off formulations as well as creams, gels, and lotions.
Methyl Gluceth DOE 120KC is designed specifically for use with infant care products, such as bath and shampoo.
Methyl Gluceth DOE 120KC gives hair care products including conditioners, treatments, shampoos, and rinses a luxuriant texture and enhanced viscosity.
Methyl Gluceth DOE 120KC enhances face and skin cleansers for skin care, guaranteeing a gentle and efficient washing experience.
Methyl Gluceth DOE 120KC is a non-ionic thickener, a naturally derived glucoside product.
Methyl Gluceth DOE 120KC has good compatibility, does not reduce the foam of surfactant system, has good compounding and thickening effect with AOS, AES sodium salt, sulfosuccinate salt and amphoteric surfactant, no jelly feeling, excellent Synergy.

PEG-120 Methyl Glucose Dioleate Thickener has zero eye irritation test results, proving that Methyl Gluceth DOE 120KC is completely non-irritating to the eyes, making it an ideal ingredient for baby shampoos.
In addition, the addition of Methyl Gluceth DOE 120KC thickener to the formulation significantly reduces eye irritation caused by strong harsh surfactants.

Methyl Gluceth DOE 120KC thickener has multiple functions of increasing viscosity and reducing CI, and is often used in cleaning products.
Formulators can use Methyl Gluceth DOE 120KC to formulate products that are easy to pour and provide foam aesthetics without the concern of altering foam characteristics.
Methyl Gluceth DOE 120KC is the polyethylene glycol ether of the diester of natural Methylglucose and Oleic Acid.
Methyl Gluceth DOE 120KC is used in cosmetics as a surfactant, thickener, and emulsifier.
Methyl Gluceth DOE 120KC can reduce the irritation value of the entire formulation.
Methyl Gluceth DOE 120KC's high molecular weight makes it impenetrable to healthy skin.
Methyl Gluceth DOE 120KC is available as a flaky solid or a liquid.

Methyl Gluceth DOE 120KC is used as a surfactant and emulsifier in many cosmetic products.
Methyl Gluceth DOE 120KC provides stability to the product and prevents the oil and water-based components of the product from separating out.
Methyl Gluceth DOE 120KC is an extremely effective, non-ionic, liquid thickener that can be used in numerous surfactant and emulsion systems.
Methyl Gluceth DOE 120KC is typically used at 0.5-3%, depending on the application.

Skin care: Methyl Gluceth DOE 120KC creates a thin layer on the skin forming a barrier.
Methyl Gluceth DOE 120KC protects the skin from moisture loss and increases its water retention capacity thereby making it softer and healthier
Hair care: Methyl Gluceth DOE 120KC conditions the hair and makes them soft and silky.
As a surfactant, Methyl Gluceth DOE 120KC helps the dirt particles trapped on the skin with oil to get mixed with water, so that it gets away rinsed easily with water and is useful for shampoo formulations.
Methyl Gluceth DOE 120KC also thickens the hair product.

Methyl Gluceth DOE 120KC is a non-ionic thickener, a naturally derived glucoside product.
Methyl Gluceth DOE 120KC has good compatibility, does not reduce the foam of surfactant system, has good compounding and thickening effect with AOS, AES sodium salt, sulfosuccinate salt and amphoteric surfactant, no jelly feeling, excellent Synergy.
Methyl Gluceth DOE 120KC has zero eye irritation test results, proving that it is completely non-irritating to the eyes, making it an ideal ingredient for baby shampoos.
In addition, the addition of Methyl Gluceth DOE 120KC thickener to the formulation significantly reduces eye irritation caused by strong harsh surfactants.
Methyl Gluceth DOE 120KC thickener has multiple functions of increasing viscosity and reducing CI, and is often used in cleaning products.
Formulators can use Methyl Gluceth DOE 120KC to formulate products that are easy to pour and provide foam aesthetics without the concern of altering foam characteristics.
METHYL GLUCETH-10
DESCRIPTION:
METHYL GLUCETH-10 is A pale yellow, corn-derived liquid that works as a humectant ingredient helping the skin to cling onto water.
METHYL GLUCETH-10 has a smooth, silky feel and can reduce the tackiness of other humectants.
METHYL GLUCETH-10 humectant is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.


CAS Number: 68239-42-9
EINECS: 7-759
Chem/IUPAC Name: Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, ether with methyl .beta.-d-glucopyranoside (4:1)

CHEMICAL AND PHYSICAL PROPERTIES OF METHYL GLUCETH-10:
Molecular Formula: C15H30O10
Molecular Weight: 370.39
IUPAC Name:
2-[[3,4,5-tris(2-hydroxyethoxy)-6-methoxyoxan-2-yl]methoxy]ethanol
Molecular Weight: 370.39
XLogP3-AA: -3.2
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 10
Rotatable Bond Count: 14
Exact Mass: 370.18389715
Monoisotopic Mass: 370.18389715
Topological Polar Surface Area: 136 Ų
Heavy Atom Count: 25
Formal Charge: 0
Complexity: 319
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 5
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
XlogP3-AA: -3.20 (est)
Molecular Weight: 370.39610000
Formula: C15 H30 O10
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 562.00 to 563.00 °C. @ 760.00 mm Hg (est)
Flash Point: 561.00 °F. TCC ( 294.00 °C. ) (est)
logP (o/w): -4.430 (est)
Soluble in:
water, 1e+006 mg/L @ 25 °C (est)
Appearance: Light, Viscous Liquid
Color, APHA:Max. 80
Hydroxyl value:160-180
Saponification value, mg/g:Max. 1.0
Acid value:Max. 1.0
Water content, %:Max. 1.0
Iodine value:Max. 1.0
Ash, % WT. : Max. 0.5




METHYL GLUCETH-10 is an ethoxylated methyl glucose ether and is 100% active.
Its low irritation potential makes METHYL GLUCETH-10 ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.

USAGE OF METHYL GLUCETH-10:
METHYL GLUCETH-10 is Used in skin care products in all formulas.
Methyl Gluceth-10 is an extremely effective humectant for both rinse off and leave on products.

It is recommended for use in skin care products including lotions, creams and body cleansing formulations as well as in hair care styling formulations.
Moreover Methyl Gluceth-10 helps to form emulsions by reducing the surface tension of the substances to be emulsified.
METHYL GLUCETH-10 is mainly used in our styling products.

BENEFITS OF METHYL GLUCETH-10:
METHYL GLUCETH-10 is Very effective water-retention properties that help prevent water-loss from the skin
METHYL GLUCETH-10 Enhances spreadability of products
METHYL GLUCETH-10 Can significantly reduce skin irritation associated with any anionic and amphoteric surfactants

METHYL GLUCETH-10 has Excellent emollient properties providing a smooth and gentle skin feel
METHYL GLUCETH-10 Has also thickening and emulsifying properties

APPLICATIONS OF METHYL GLUCETH-10:
• Lotions
• Creams
• After-shave products
• Bar soaps
• Bath products
• Shampoos and cleansing products

MEG E-10 is an extremely effective humectant for skin care systems.
MEG E-10 provides the following characteristics to formulations:
• Improved after feel
• Reduced defatting of the skin
• Light, smooth feel
• Prevents cracking in bar soap applications
• Effective processing aid for soap manufacture

MIXING METHOD:
METHYL GLUCETH-10 Mix in the water
METHYL GLUCETH-10 Can withstand heat
METHYL GLUCETH-10 Can be formulated with a pH range of 3-10 (can be used with bar soaps).

RATE OF USE: 0.5-5% ( Use High levels of Methyl Gluceth-10 of more than 2% can cause a sensation of skin heat.
But it doesn't cause any allergy or irritation. )
Product characteristics: Semi-condensed liquid
Solubility: METHYL GLUCETH-10 Can dissolve in water

STORAGE:
METHYL GLUCETH-10 Can be stored at room temperature But close the bottle tightly And sealed from direct sunlight or heat, the product is at least 2 years old

SAFETY INFORMATION ABOUT METHYL GLUCETH-10:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.



METHYL GLUCETH-10
Methyl Gluceth-10 is a cosmetic ingredient that belongs to the family of polyethylene glycol (PEG) ethers of methyl glucose.
Methyl Gluceth-10 a pale yellow, corn-derived liquid that works as a humectant ingredient helping the skin to cling onto water.
Methyl Gluceth-10 has a smooth, silky feel and can reduce the tackiness of other humectants.

CAS Number: 68239-42-9
Molecular Formula: C15H30O10
Molecular Weight: 370.3927

Methyl Gluceth-10 is ethoxylated methyl glucose ether is Humectant helps retain moisture for the skin all day long.
Suitable for use in all skin care formulas.
Natural glucose derivative made as Methyl Gluceth-10.

Due to its exceptional water retention properties methyl gluceth-10 offers a very smooth and gentle skin feel and can be used in various skin and hair care products.
Methyl Gluceth-10 pale yellowish viscous liquid.
Methyl Gluceth-10 is water-soluble.

Methyl Gluceth-10 is a natural GLUCO™se derivative from corn, acting as favorable, mild and no-irritation moisturizer ingredient.
Methyl Gluceth-10 is an outstanding emollient, can impart finished-product gloss and refreshing after-feeling and will decrease tacky feel of a formula.

Methyl Gluceth-10 applied in cream, eye cream, styling product, shampoo, body wash, facial cleanser, skin tonic, alcoholic product, soap, hair treatment and conditioner.
Methyl Gluceth-10 also acts as a good antifreeze agent.

Methyl Gluceth-10 by MakingCosmetics acts as an emollient and moisturizing agent.
Methyl Gluceth-10 is a natural glucose derivative produced as polyethylene glycol ether of methyl glucose.
Methyl Gluceth-10 shows very effective water-retention properties which help to prevent water loss from the skin.

Methyl Gluceth-10 also exhibits thickening- and emulsifying properties.
Methyl Gluceth-10 enhances spreadability of products and imparts a smooth & gentle skin feel.
Methyl Gluceth-10 can significantly reduce skin irritation associated with any anionic and amphoteric surfactants.

Methyl Gluceth-10 is used in lotions & creams, after-shave products, bar soaps, bath products, shampoos and cleansing products.
Methyl Gluceth-10 is vegan certified and preservative-free grade.
Natural glucose derivative made as polyethylene glycol ether of Methyl Gluceth-10.

Methyl Gluceth-10 humectant is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.
Methyl Gluceth-10 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-10 is low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.

Methyl Gluceth-10 is valued for its humectant properties, meaning it helps attract and retain moisture.
This can contribute to keeping the skin hydrated and may be particularly beneficial in moisturizing formulations.
As an emollient, Methyl Gluceth-10 can contribute to the smoothness and softness of the skin by forming a protective barrier.

This barrier helps to prevent water loss and enhances the overall texture of skincare products.
Methyl Gluceth-10 is often used in combination with other ingredients in formulations because of its compatibility with various cosmetic ingredients.
This versatility makes it a popular choice for formulators.

Methyl Gluceth-10 is derived from natural sources such as glucose and methyl alcohol.
This can be appealing to consumers looking for products with ingredients sourced from renewable and sustainable resources.
This ingredient is generally considered to be mild and well-tolerated, making it suitable for a range of skin types.

However, individual sensitivities can vary, so Methyl Gluceth-10's always recommended to perform a patch test when trying new skincare products.
Methyl gluceth-10 is a PEG ether of methyl glucose Methyl gluceth-10 uses and applications include: Emulsifier, humectant, moisturizer, emollient for cosmetics, personal care products; freezing pt. depressant; foam modifier in detergents and shampoos; solvent and solubilizer for topical pharmaceuticals.
Methyl Gluceth-10 is an extremely effective humectant for both rinse off and leave on products.

Methyl Gluceth-10 is recommended for use in skin care products including lotions, creams and body cleansing formulations as well as in hair care styling formulations.
Moreover Methyl Gluceth-10 helps to form emulsions by reducing the surface tension of the substances to be emulsified.
Methyl Gluceth-10's mainly used in our styling products.

Methyl Gluceth-10 is an ingredient in some types of soaps and personal care products.
Methyl Gluceth-10 is used as a substantive conditioning humectant.
This chemical is a type of methyl glucoside derivative, which has been modified by ethoxylation and quaternization.

Methyl Gluceth-10 a synthetic pathway for lauryl methyl gluceth-10 hydroxypropyldimonium chloride and other methyl glucoside humectants has been outlined in trade literature.
Methyl Gluceth-10 is listed as a trade-named raw material, Glucquat 125, in cosmetic and toiletry products.
Methyl Gluceth-10 is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.

Methyl Gluceth-10 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-10 is low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.
Methyl Gluceth-10 is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.

Methyl Gluceth-10 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-10 is low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.
Methyl Gluceth-10 is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.

Methyl Gluceth-10 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-10 is low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.
Methyl Gluceth-10 by Lubrizol is a mild humectant, film plasticizer and moisturizer.

Methyl Gluceth-10 is naturally derived and delivers moisture to the skin while reducing the tacky feel.
Methyl Gluceth-10 is an ethoxylated methyl glucose ether.
Methyl Gluceth-10 offers low irritation, gloss and smooth silky feel.

Methyl Gluceth-10 is a very effective freezing point depressant and does not interfere with foam properties.
Methyl Gluceth-10 is ideal for use in both rinse off and leave on skin care systems.
Methyl Gluceth-10is used in body lotions/creams/gels, body cleansing formulations, color cosmetics, hair removal, hand sanitizer and intimate & mild cleansers.

Methyl Gluceth-10 is commonly used in skincare and personal care products, such as lotions, creams, and cleansers.
This ingredient is known for its moisturizing properties and its ability to enhance the spreadability of products on the skin.
Methyl Gluceth-10 is derived from natural sources, specifically glucose and methyl alcohol.

Methyl Gluceth-10 is often used to improve the overall feel and texture of skincare formulations, making them smoother and more comfortable to apply.
Also, used in hand soaps, wipes, shaving & styling products, eye-, facial-, hand/foot-, lip- and sun care products.
Methyl Gluceth-10 is a substance that promotes the retention of moisture on the skin.

This increased moisture can increase an active ingredient’s solubility, which can then in turn increase the skin penetration.
These ingredients deliver light, satiny after-feel to skin formulations and are effective at reducing the tack of glycerin.
There are several creams on the market containing these IID-listed humectants and formulated with a variety of APIs.

Methyl Gluceth-10 is a natural glucose derivative from corn, acting as favorable, mild and no-irritation moisturizer ingredient.
Methyl Gluceth-10 is an outstanding emollient, can impart finished-product gloss and refreshing after-feeling and will decrease tacky feel of a formula.
Applied in cream, eye cream, styling product, shampoo, body wash, facial cleanser, skin tonic, alcoholic product, soap, hair treatment and conditioner.

Methyl Gluceth-10 also acts as a good antifreeze agent.
Methyl gluceth-20 is made by combining polyethylene glycol with glucose to create a new compound.
In cosmetics, Methyl Gluceth-10 functions as a humectant and conditioning ingredient.

Methyl Gluceth-10 low irritation potential makes it ideal for sensitive skin formulations.
The independent Cosmetic Ingredient Review panel has found Methyl Gluceth-10 safe as used in cosmetics, where concentrations range from 4–15%, with rinse-off products typically containing greater amounts.
Methyl Gluceth-10 is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.

Methyl Gluceth-10 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-10 is low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.
Glucose moisturizers including Methyl Gluceth-10 and methyl gluceth-20 are esters of methyl glucose that can be naturally derived from botanical sources including corn or can be manufactured from corn sugar and starch.

Methyl Gluceth-10 and methyl gluceth-20 are pale yellow liquids.
Methyl Gluceth-10 is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.
Methyl Gluceth-10 is an ethoxylated methyl glucose ether and is 100% active.

Methyl Gluceth-10's low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.
Methyl Gluceth-10 is often used in combination with other ingredients to create synergistic effects.
For example, Methyl Gluceth-10 may be included in formulations alongside other humectants, emollients, or active ingredients to enhance overall skincare benefits.

One of the advantages of using Methyl Gluceth-10 in formulations is its non-greasy feel.
This can be particularly appealing in skincare products, as it allows for a lightweight and comfortable application.
The polyol structure of Methyl Gluceth-10, derived from glucose, contributes to its moisturizing properties.

Methyl Gluceth-10s are compounds that contain multiple hydroxyl groups, which can attract and retain water, aiding in skin hydration.
In addition to its moisturizing and emollient properties, Methyl Gluceth-10 can also serve as a thickening agent in cosmetic formulations.
This is beneficial for achieving the desired consistency and texture in various skincare products.

Methyl Gluceth-10 is a compound that contains a sugar (carbohydrate) molecule which are convertible into sugar (called glycone) and a nonsugar component (called aglycon or genin) by hydrolytic cleavage.
The glycone can consist of a monosaccharide (single sugar component) or oligosaccharide (several sugar groups).
Methyl Gluceth-10 play important roles in living organisms, and thus numerous natural glycosides are studied for medication applications.

Methyl Gluceth-10 is a glycoside in which the sugar constituent is glucose.
Methyl Gluceth-10 and fructoside are glycosides in which the sugar constituents are pentose and fructose respectively.
Methyl Gluceth-10 is used as initiators in the manufacture of rigid polyurethane foams.

Methyl Gluceth-10 also widely used in the synthesis of surfactants.
Methyl Gluceth-10 is effective humectants and viscosity modifiers with low irritant and silky feeling on the skin.

They are recommended for use in both rinse and skin care products such as lotions, creams, shampoo, and body cleanser.
Methyl Gluceth-10 is a component of emulsifier applied for personal care products, skin creams, lotions and other cosmetics, particularly for leave on skin care systems to reduce tacky feel and synergistic humectancy performance.

Odor: at 100.00?%. bland
LogP: -4.430 (est)
EWG's Food Scores: 1

Methyl Gluceth-10 is a natural glucose derivative made as polyethylene glycol ether of methyl glucose.
Very effective water-retention properties that help prevent water-loss from the skin.
Can significantly reduce skin irritation associated with any anionic and amphoteric surfactants.

Excellent emollient properties providing a smooth and gentle skin feel.
Has also thickening and emulsifying properties.
Methyl Gluceth-10 is made by combining polyethylene glycol with glucose to create a new compound.

In cosmetics, Methyl Gluceth-10 functions as a humectant and conditioning ingredient.
According to its manufacturer, Methyl Gluceth-10 low irritation potential makes it ideal for sensitive skin formulations.
In addition to its moisturizing properties, Methyl Gluceth-10 can also act as a surfactant.

Surfactants help to reduce the surface tension of liquids, allowing them to spread more easily.
This property can contribute to the even distribution of a product on the skin.
Methyl Gluceth-10 can enhance the stability of formulations.

Methyl Gluceth-10 is presence in cosmetic products can contribute to maintaining the integrity and quality of the product over time, preventing it from separating or undergoing undesirable changes.
Methyl Gluceth-10 can help stabilize the pH of formulations.
Maintaining the proper pH is crucial for the effectiveness and skin compatibility of cosmetic products.

This ingredient is found in a wide range of skincare and personal care products, including facial cleansers, body lotions, serums, and hair care products.
Methyl Gluceth-10 is versatility makes it suitable for different types of formulations.
This ingredient is water-soluble, which means it can dissolve in water.

This solubility can be advantageous in formulations where water is a major component, such as in lotions and creams.
Methyl Gluceth-10 is commonly found in various personal care and cosmetic products, including moisturizers, cleansers, toners, and other skincare formulations.
Methyl Gluceth-10 is versatility and compatibility with other ingredients make it a popular choice for formulators.

Methyl Gluceth-10, are subject to regulations to ensure their safety and efficacy.
Regulatory bodies in different regions may have specific guidelines and restrictions on the use of cosmetic ingredients, and formulators must adhere to these regulations when creating products for the market.
Methyl Gluceth-10 is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.

Methyl Gluceth-10 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-10 is low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.
Methyl Gluceth-10 is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.

Methyl Gluceth-10 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-10 is low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.
Methyl Gluceth-10 is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.

Methyl Gluceth-10 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-10 is low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.
Methyl Gluceth-10 is a naturally-derived, multi-functional, mild ingredient that delivers a light, satin-like emollient feel in moisturizing systems.

Methyl Gluceth-10 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-10 is low irritation potential makes it ideal for sensitive skin formulations.
In addition, Methyl Gluceth-10 helps prevent soap bars from cracking and acts as a process aid in soap bar extrusion.

Methyl Gluceth-10 is a natural component of the stratum corneum layers of skin that binds water and hydrates skin.
Methyl Gluceth-10 is a component of what are called “natural moisturizing factors” or NMF.
Methyl Gluceth-10 moisturizers, including Methyl gluceth-10 and -20, are naturally derived water-soluble emollients, humectants and moisturizers.

Methyl Gluceth-10 is a corn-based naturally derived emollient noted for its safety and mildness that imparts a smooth and silky feel on the skin.
Methyl Gluceth-10s also improve the richness of shampoos and enhance the foaming properties of cleansers.
Methyl Gluceth-10 is considered a special moisturizing agent used particularly for its moisture retentive qualities and as a surfactant in skin creams and other cosmetics to open pores and follicles.

Methyl Gluceth-10s are frequently used in creams and cosmetics along with other ingredients to improve skin hydration.
Other natural moisturizing factors include amino acids, carboxylic pyrrolidone acid, lactic acid, urea, and mineral ions.
The natural moisturizing factors contained in the corneocytes of skin are formed during epidermal skin cell differentiation and may represent up to ten percent of corneocyte cell mass.

The binding of water to natural moisturizing factors in skin is considered by experts to be the static aspect of cutaneous hydration.
Methyl Gluceth-10 is a water-soluble liquid moisturizer and emollient.

As an ingredient in cosmetic formulations, Methyl Gluceth-10 imparts a smooth and gentle skin feel.
Due to its exceptional water retention properties, Methyl Gluceth-10 finds uses in lotions, creams, after-shave products, bar soaps, bath products, hair wave products and cleansing products.

Uses:
Use High levels of Methyl Gluceth-10 of more than 2% can cause a sensation of skin heat.
In some users But it doesn't cause any allergy or irritation.
Methyl Gluceth-10 is a skin humectant and a preservative.

This is the polyethylene glycol ether of Methyl Gluceth-10.
Methyl Gluceth-10 can be used added to formulas as is.
Methyl Gluceth-10 is often included in moisturizing products such as creams, lotions, and serums.

Methyl Gluceth-10 is humectant properties help attract and retain moisture, promoting hydration and preventing dryness.
This ingredient can be found in facial cleansers and body washes.
Methyl Gluceth-10 is surfactant properties contribute to the even distribution of the product on the skin, and its emollient properties can provide a smooth and gentle cleansing experience.

Methyl Gluceth-10 is used in toners to add hydration and improve the skin feel.
Toners with this ingredient may help balance the skin's moisture levels after cleansing.
Formulators often choose Methyl Gluceth-10 for its versatility in adjusting the consistency and texture of cosmetic products.

Methyl Gluceth-10 is use can contribute to achieving the desired viscosity and spreadability in various formulations.
The humectant properties of Methyl Gluceth-10 can help regulate moisture content on the skin's surface, making it suitable for products designed to provide hydration in different climates and environmental conditions.
Because of its lightweight and non-greasy feel, products containing Methyl Gluceth-10 are often suitable for layering in a skincare routine.

Individuals can comfortably apply multiple products without feeling heavy or sticky.
Methyl Gluceth-10 can contribute to the overall sensorial experience of a product.
Methyl Gluceth-10 is inclusion can result in formulations that feel pleasant on the skin, encouraging regular use.

Methyl Gluceth-10 is compatible with a wide range of cosmetic ingredients, including active compounds and other moisturizing agents.
This compatibility allows formulators to create complex formulations that address multiple skincare needs.
As a derivative of glucose and methyl alcohol, Methyl Gluceth-10 is generally considered to be more biodegradable compared to some synthetic alternatives.

This aspect aligns with growing consumer preferences for environmentally friendly cosmetic ingredients.
Cosmetic formulators consider Methyl Gluceth-10's compliance with regulations in various regions.
Meeting regulatory standards ensures that products containing this ingredient can be marketed globally.

The non-greasy and lightweight feel of products containing Methyl Gluceth-10 can positively influence consumer perception.
Products with these attributes are often favored by those who prefer a comfortable and easily absorbed skincare experience.
Methyl Gluceth-10 is sometimes included in hair care formulations such as conditioners and shampoos to provide conditioning and a smooth texture.

Methyl Gluceth-10 is water-soluble nature makes it suitable for rinse-off hair care products.
Methyl Gluceth-10 can be part of serum formulations, contributing to the overall texture and spreadability of the product.
Methyl Gluceth-10 is moisturizing properties can enhance the serum's ability to hydrate the skin.

Methyl Gluceth-10 is included in sunscreen formulations.
Methyl Gluceth-10 is emollient properties can contribute to the even application of the sunscreen, and its humectant properties can help maintain skin hydration.
Due to its stabilizing properties, Methyl Gluceth-10 can be used to enhance the stability of various formulations, preventing ingredient separation or changes in texture over time.

Methyl Gluceth-10 may be found in certain makeup formulations, such as foundations, concealers, and tinted moisturizers.
Methyl Gluceth-10 is emollient properties can contribute to a smoother application, while its humectant properties help maintain skin hydration.
In skincare masks, particularly hydrating masks, Methyl Gluceth-10 can play a role in providing a moisture boost to the skin.

Methyl Gluceth-10 contributes to the overall texture and feel of the mask.
Due to its moisturizing and skin-conditioning properties, Methyl Gluceth-10 can be included in pre-shave and after-shave products.
Methyl Gluceth-10 helps prepare the skin for shaving and provides post-shave hydration.

Methyl Gluceth-10's mild and hydrating properties make it suitable for use in baby care products such as baby lotions, creams, and mild cleansers.
Given its generally mild nature, Methyl Gluceth-10 may be used in products designed for individuals with sensitive skin.
Methyl Gluceth-10 can contribute to the gentleness of formulations.

In some formulations for intimate care products, Methyl Gluceth-10 can contribute to a comfortable and moisturizing experience.
Methyl Gluceth-10 is surfactant properties make Methyl Gluceth-10 suitable for inclusion in body washes and shower gels, contributing to effective cleansing and a pleasant skin feel.
Methyl Gluceth-10 is often included in multi-functional products that aim to provide various skincare benefits in one formulation, such as combining hydration with other active ingredients.

Methyl Gluceth-10 is often included in formulations with active ingredients, such as antioxidants, vitamins, or peptides.
Methyl Gluceth-10 is compatibility with these actives allows for the creation of comprehensive skincare products that address multiple concerns.
Methyl Gluceth-10 can contribute to stabilizing fragrances, helping to maintain the scent integrity of the product over time.

Methyl Gluceth-10 is water-soluble nature and moisturizing properties make Methyl Gluceth-10 suitable for inclusion in some sunscreens and sun care products.
Methyl Gluceth-10 can enhance the application experience and provide additional skin conditioning.
Formulators often use Methyl Gluceth-10 to enhance the overall aesthetics of a product.

This includes factors such as the color, texture, and appearance, contributing to a visually appealing final product.
The inclusion of Methyl Gluceth-10 in formulations can aid in the delivery of other active ingredients into the skin.
This can be particularly important in products designed to target specific skin concerns.

Due to its mild and hydrating properties, products containing Methyl Gluceth-10 may be suitable for post-procedure skincare, providing a soothing and moisturizing effect.
Dermatologists may recommend products containing Methyl Gluceth-10 for individuals with specific skin conditions or sensitivities, owing to its generally gentle nature.
Methyl Gluceth-10 is widely accepted in the cosmetics industry globally, making it a common ingredient in products available in various markets.

Individuals interested in DIY skincare formulations may choose to incorporate Methyl Gluceth-10 for its emollient and humectant properties, adding it to their creations to achieve desired skincare benefits.
Methyl Gluceth-10 might be included in anti-aging formulations to provide hydration and improve the overall feel of the product on the skin.
Methyl Gluceth-10 is non-greasy feel makes it suitable for inclusion in products designed for daily use.

Safety Profile:
While Methyl Gluceth-10 is known for its mild nature, some individuals may be sensitive or allergic to certain cosmetic ingredients.
Methyl Gluceth-10's recommended to perform a patch test before using a product with Methyl Gluceth-10, especially for those with sensitive skin.
Avoid direct contact with the eyes, as some cosmetic ingredients, including Methyl Gluceth-10, may cause irritation.

Individuals with known allergies to specific components or chemical compounds should carefully review product labels for potential allergens.
Products containing Methyl Gluceth-10 should adhere to regulatory standards set by relevant authorities.
Cosmetic formulations must meet safety guidelines and ingredient restrictions.

The overall safety of a product depends on its complete formulation.
Methyl Gluceth-10's essential to consider the concentration of Methyl Gluceth-10 and its interactions with other ingredients in the product.
While Methyl Gluceth-10 is considered biodegradable, the environmental impact of cosmetic ingredients is an evolving area of concern.

Synonyms:
Methyl gluceth
68239-42-9
2-[[(2R,6R)-3,4,5-tris(2-hydroxyethoxy)-6-methoxyoxan-2-yl]methoxy]ethanol
SCHEMBL9780103
DTXSID80941306
Methyl 2,3,4,6-tetrakis-O-(2-hydroxyethyl)hexopyranoside
195378-75-7
METHYL GLUCETH-20
DESCRIPTION:

Methyl gluceth-20 is an ether of methyl glucose with polyethylene glycol.
Methyl gluceth-20 can also be derived from corn.
Methyl gluceth-20 has great water retention properties.

CAS Number, 68239-42-9
European Community (EC) Number: 614-384-8
Chem/IUPAC Name:, Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, ether with methyl .beta.-d-glucopyranoside (4:1)
Molecular Formula: C15H30O10


Methyl gluceth-20 comes as a pale-yellow viscous liquid.
Methyl gluceth-20 has a faint odor.

USE & BENEFITS OF METHYL GLUCETH-20:
Since Methyl gluceth-20 has tremendous water retention capacity, it is very useful from a formulation point of view.
Methyl gluceth-20 helps with the soft and unbreakable structure of bath soap, smoother texture in lotions and creams.
Methyl gluceth-20 has significant numbers of hydroxyl groups (-OH) in its structure, so it can form a bond with water molecules and that's how it can attract more water.


When applied on the skin, Methyl gluceth-20 draws moisture from the surrounding environment and makes it available for the skin.
For dry skin, it imparts moisture and also does not let it escape by forming a film on the skin surface.

Methyl gluceth-20 gives a gentle and smooth feel to the skin, which is peculiar to this ingredient.
Methyl gluceth-20 is used in Creams, lotions, aftershave products, bathing soaps, cleansing products and hair wave products.


Methyl gluceth-20 is made by combining polyethylene glycol with glucose to create a new compound.
In cosmetics, it functions as a humectant and conditioning ingredient.
According to its manufacturer, methyl gluceth-20’s (also known by its trade name, Glucam ™ E-20) low irritation potential makes it ideal for sensitive skin formulations.

The independent Cosmetic Ingredient Review panel has found methyl gluceth-20 safe as used in cosmetics, where concentrations range from 4–15%, with rinse-off products typically containing greater amounts.


Methyl Gluceth-20 is a water soluble emollient and humectant produced from Glucose and Methyl Alcohol and originally derived from corn sugar and corn starch.
Methyl Gluceth-20 is a versatile, gentle, effective humectant, emollient, and foaming agent that imparts a smooth feel to the skin.
Methyl Gluceth-20 is specifically used for its moisture retentive qualities and ability to open pores and follicles




Methyl Gluceth-20 Is ethoxylated methyl glucose ether is Humectant helps retain moisture for the skin all day long.
Methyl Gluceth-20 Is Suitable for use in all skin care formulas.
Both leave-on and wash-off formulas.

Use High levels of Methyl Gluceth-20, more than 2%, can cause a sensation of skin heat.
In some users But Methyl Gluceth-20 doesn't cause any allergy or irritation.



Methyl Gluceth-20 is Polyethylene glycol ether of methyl glucose.
Methyl Gluceth-20 is a water-soluble liquid moisturizer and emollient.
Methyl Gluceth-20 is used As an ingredient in cosmetic formulations,

Methyl Gluceth-20 imparts a smooth and gentle skin feel.
Due to its exceptional water retention properties, it finds uses in lotions, creams, after-shave products, bar soaps, bath products, hair wave products and cleansing products.



SAFETY INFORMATION ABOUT METHYL GLUCETH-20:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product








CHEMICAL AND PHYSICAL PROPERTIES OF METHYL GLUCETH-20:
Appearance, Light, Viscous Liquid
Color, APHA, Max. 80
Hydroxyl value, 205-225
Saponification value, mg/g, Max. 1.0
Acid value, Max. 1.0
Water content, %, Max. 1.0
Iodine value, Max. 1.0
Ash, % WT., Max. 0.5
Origin: Synthetic
Shelf life: 2 years from mfg. date
Freight Classification: NMFC 43940 S 2 CL 85
Kosher Status: Not Kosher
Flash Point: >175ø C
Melting Point: N/A
API: NO
Allergen: NO
Hazmat: YES
Molecular Weight: 370.39 g/mol
Molecular Weight
370.39 g/mol
XLogP3-AA
-3.2
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
10
Rotatable Bond Count
14
Exact Mass
370.18389715 g/mol
Monoisotopic Mass
370.18389715 g/mol
Topological Polar Surface Area
136Ų
Heavy Atom Count
25
Formal Charge
0
Complexity
319
Isotope Atom Count
0
Defined Atom Stereocenter Count
2
Undefined Atom Stereocenter Count
3
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes

Usage: Used in skin care products in all formulas.
Mixing method: Mix in the water Can withstand heat Can be formulated with a pH range of 3-10 (can be used with bar soaps).
Rate of use: 0.5-5% ( Use High levels of Methyl Gluceth-20, more than 2%, can cause a sensation of skin heat. But it doesn't cause any allergy or irritation. )
Product characteristics: Semi-condensed liquid
Solubility: Can dissolve in water
Storage: Can be stored at room temperature But close the bottle tightly And sealed from direct sunlight or heat, the product is at least 2 years old









SYNONYMS OF METHYL GLUCETH-20:
Methyl gluceth
68239-42-9
2-[[(2R,6R)-3,4,5-tris(2-hydroxyethoxy)-6-methoxyoxan-2-yl]methoxy]ethanol
SCHEMBL9780103
DTXSID80941306
Methyl 2,3,4,6-tetrakis-O-(2-hydroxyethyl)hexopyranoside
195378-75-7




METHYL GLUCETH-20
Methyl Gluceth-20 a pale yellow, corn-derived liquid that works as a humectant ingredient helping the skin to cling onto water.
Methyl Gluceth-20 is a cosmetic ingredient that belongs to the family of polyethylene glycol (PEG) ethers of methyl glucose.
Methyl Gluceth-20 pale yellowish viscous liquid.

CAS Number: 68239-42-9
Molecular Formula: C15H30O10
Molecular Weight: 370.3927

Methyl gluceth, 68239-42-9, 2-[[(2R,6R)-3,4,5-tris(2-hydroxyethoxy)-6-methoxyoxan-2-yl]methoxy]ethanol SCHEMBL9780103, DTXSID80941306, Methyl 2,3,4,6-tetrakis-O-(2-hydroxyethyl)hexopyranoside,195378-75-7.

Methyl Gluceth-20 is ethoxylated methyl glucose ether is Humectant helps retain moisture for the skin all day long.
Suitable for use in all skin care formulas.
Methyl Gluceth-20 is water-soluble.

Methyl Gluceth-20 is a natural GLUCO™se derivative from corn, acting as favorable, mild and no-irritation moisturizer ingredient.
Methyl Gluceth-20 is often used in combination with other ingredients in formulations because of its compatibility with various cosmetic ingredients.

This versatility makes it a popular choice for formulators.
Methyl Gluceth-20 is derived from natural sources such as glucose and methyl alcohol.
This can be appealing to consumers looking for products with ingredients sourced from renewable and sustainable resources.

This ingredient is generally considered to be mild and well-tolerated, making it suitable for a range of skin types.
However, individual sensitivities can vary, so Methyl Gluceth-20's always recommended to perform a patch test when trying new skincare products.
Methyl Gluceth-20 is a PEG ether of methyl glucose Methyl Gluceth-20 uses and applications include: Emulsifier, humectant, moisturizer, emollient for cosmetics, personal care products; freezing pt. depressant; foam modifier in detergents and shampoos; solvent and solubilizer for topical pharmaceuticals.

Methyl Gluceth-20 is an extremely effective humectant for both rinse off and leave on products.
Methyl Gluceth-20 is recommended for use in skin care products including lotions, creams and body cleansing formulations as well as in hair care styling formulations.
Moreover Methyl Gluceth-20 helps to form emulsions by reducing the surface tension of the substances to be emulsified.

Methyl Gluceth-20's mainly used in our styling products.
Methyl Gluceth-20 is an ingredient in some types of soaps and personal care products.
Methyl Gluceth-20 is used as a substantive conditioning humectant.

Methyl Gluceth-20 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-20 is low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.
Methyl Gluceth-20 by Lubrizol is a mild humectant, film plasticizer and moisturizer.

Methyl Gluceth-20 is naturally derived and delivers moisture to the skin while reducing the tacky feel.
Methyl Gluceth-20 is an ethoxylated methyl glucose ether.
Methyl Gluceth-20 offers low irritation, gloss and smooth silky feel.

Methyl Gluceth-20 is a very effective freezing point depressant and does not interfere with foam properties.
Methyl Gluceth-20 is ideal for use in both rinse off and leave on skin care systems.
Methyl Gluceth-20is used in body lotions/creams/gels, body cleansing formulations, color cosmetics, hair removal, hand sanitizer and intimate & mild cleansers.

Methyl Gluceth-20 is commonly used in skincare and personal care products, such as lotions, creams, and cleansers.
This ingredient is known for its moisturizing properties and its ability to enhance the spreadability of products on the skin.
Methyl Gluceth-20 is derived from natural sources, specifically glucose and methyl alcohol.

Methyl Gluceth-20 is often used to improve the overall feel and texture of skincare formulations, making them smoother and more comfortable to apply.
Also, used in hand soaps, wipes, shaving & styling products, eye-, facial-, hand/foot-, lip- and sun care products.
Methyl Gluceth-20 is a substance that promotes the retention of moisture on the skin.

This increased moisture can increase an active ingredient’s solubility, which can then in turn increase the skin penetration.
These ingredients deliver light, satiny after-feel to skin formulations and are effective at reducing the tack of glycerin.
There are several creams on the market containing these IID-listed humectants and formulated with a variety of APIs.

Methyl Gluceth-20 is a natural glucose derivative from corn, acting as favorable, mild and no-irritation moisturizer ingredient.
Methyl Gluceth-20 is an outstanding emollient, can impart finished-product gloss and refreshing after-feeling and will decrease tacky feel of a formula.
Applied in cream, eye cream, styling product, shampoo, body wash, facial cleanser, skin tonic, alcoholic product, soap, hair treatment and conditioner.

Methyl Gluceth-20 also acts as a good antifreeze agent.
Methyl gluceth-20 is made by combining polyethylene glycol with glucose to create a new compound.
In cosmetics, Methyl Gluceth-20 functions as a humectant and conditioning ingredient.

Methyl Gluceth-20 low irritation potential makes it ideal for sensitive skin formulations.
The independent Cosmetic Ingredient Review panel has found Methyl Gluceth-20 safe as used in cosmetics, where concentrations range from 4–15%, with rinse-off products typically containing greater amounts.
Methyl Gluceth-20 is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.

This chemical is a type of methyl glucoside derivative, which has been modified by ethoxylation and quaternization.
Methyl Gluceth-20 a synthetic pathway for lauryl Methyl Gluceth-20 hydroxypropyldimonium chloride and other methyl glucoside humectants has been outlined in trade literature.
Methyl Gluceth-20 is listed as a trade-named raw material, Glucquat 125, in cosmetic and toiletry products.

Methyl Gluceth-20 is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.
Methyl Gluceth-20 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-20 is low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.

Methyl Gluceth-20 is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.
Methyl Gluceth-20 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-20 is low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.

Methyl Gluceth-20 is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.
Methyl Gluceth-20 is an outstanding emollient, can impart finished-product gloss and refreshing after-feeling and will decrease tacky feel of a formula.
Methyl Gluceth-20 applied in cream, eye cream, styling product, shampoo, body wash, facial cleanser, skin tonic, alcoholic product, soap, hair treatment and conditioner.

Methyl Gluceth-20 also acts as a good antifreeze agent.
Methyl Gluceth-20 by MakingCosmetics acts as an emollient and moisturizing agent.
Methyl Gluceth-20 is an ethoxylated methyl glucose ether and is 100% active.

Methyl Gluceth-20 is low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.
Glucose moisturizers including Methyl Gluceth-20 and methyl gluceth-20 are esters of methyl glucose that can be naturally derived from botanical sources including corn or can be manufactured from corn sugar and starch.
Methyl Gluceth-20 and methyl gluceth-20 are pale yellow liquids.

Methyl Gluceth-20 is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.
Methyl Gluceth-20 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-20's low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.

Methyl Gluceth-20 is often used in combination with other ingredients to create synergistic effects.
For example, Methyl Gluceth-20 may be included in formulations alongside other humectants, emollients, or active ingredients to enhance overall skincare benefits.
One of the advantages of using Methyl Gluceth-20 in formulations is its non-greasy feel.

This can be particularly appealing in skincare products, as it allows for a lightweight and comfortable application.
The polyol structure of Methyl Gluceth-20, derived from glucose, contributes to its moisturizing properties.
Methyl Gluceth-20s are compounds that contain multiple hydroxyl groups, which can attract and retain water, aiding in skin hydration.

In addition to its moisturizing and emollient properties, Methyl Gluceth-20 can also serve as a thickening agent in cosmetic formulations.
This is beneficial for achieving the desired consistency and texture in various skincare products.
Methyl Gluceth-20 is a compound that contains a sugar (carbohydrate) molecule which are convertible into sugar (called glycone) and a nonsugar component (called aglycon or genin) by hydrolytic cleavage.

The glycone can consist of a monosaccharide (single sugar component) or oligosaccharide (several sugar groups).
Methyl Gluceth-20 play important roles in living organisms, and thus numerous natural glycosides are studied for medication applications.
Methyl Gluceth-20 is a glycoside in which the sugar constituent is glucose.

Methyl Gluceth-20 and fructoside are glycosides in which the sugar constituents are pentose and fructose respectively.
Methyl Gluceth-20 is used as initiators in the manufacture of rigid polyurethane foams.
Methyl Gluceth-20 also widely used in the synthesis of surfactants.

Methyl Gluceth-20 is effective humectants and viscosity modifiers with low irritant and silky feeling on the skin.
They are recommended for use in both rinse and skin care products such as lotions, creams, shampoo, and body cleanser.
Methyl Gluceth-20 is a component of emulsifier applied for personal care products, skin creams, lotions and other cosmetics, particularly for leave on skin care systems to reduce tacky feel and synergistic humectancy performance.

Methyl Gluceth-20 is a natural glucose derivative produced as polyethylene glycol ether of methyl glucose.
Methyl Gluceth-20 shows very effective water-retention properties which help to prevent water loss from the skin.
Methyl Gluceth-20 also exhibits thickening- and emulsifying properties.

Methyl Gluceth-20 enhances spreadability of products and imparts a smooth & gentle skin feel.
Methyl Gluceth-20 can significantly reduce skin irritation associated with any anionic and amphoteric surfactants.
Methyl Gluceth-20 is used in lotions & creams, after-shave products, bar soaps, bath products, shampoos and cleansing products.

Methyl Gluceth-20 is vegan certified and preservative-free grade.
Natural glucose derivative made as polyethylene glycol ether of Methyl Gluceth-20.
Methyl Gluceth-20 humectant is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.

Methyl Gluceth-20 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-20 is low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.

Odor: at 100.00?%. bland
LogP: -4.430 (est)
EWG's Food Scores: 1

Methyl Gluceth-20 is valued for its humectant properties, meaning it helps attract and retain moisture.
Methyl Gluceth-20 is a natural glucose derivative made as polyethylene glycol ether of methyl glucose.
Very effective water-retention properties that help prevent water-loss from the skin.

Can significantly reduce skin irritation associated with any anionic and amphoteric surfactants.
Excellent emollient properties providing a smooth and gentle skin feel.
Has also thickening and emulsifying properties.

Methyl Gluceth-20 is made by combining polyethylene glycol with glucose to create a new compound.
In cosmetics, Methyl Gluceth-20 functions as a humectant and conditioning ingredient.
According to its manufacturer, Methyl Gluceth-20 low irritation potential makes it ideal for sensitive skin formulations.

In addition to its moisturizing properties, Methyl Gluceth-20 can also act as a surfactant.
Surfactants help to reduce the surface tension of liquids, allowing them to spread more easily.
This property can contribute to the even distribution of a product on the skin.

Methyl Gluceth-20 can enhance the stability of formulations.
Methyl Gluceth-20 is presence in cosmetic products can contribute to maintaining the integrity and quality of the product over time, preventing it from separating or undergoing undesirable changes.
Methyl Gluceth-20 can help stabilize the pH of formulations.

Maintaining the proper pH is crucial for the effectiveness and skin compatibility of cosmetic products.
This ingredient is found in a wide range of skincare and personal care products, including facial cleansers, body lotions, serums, and hair care products.
Methyl Gluceth-20 is versatility makes it suitable for different types of formulations.

This ingredient is water-soluble, which means it can dissolve in water.
Methyl Gluceth-20 is commonly found in various personal care and cosmetic products, including moisturizers, cleansers, toners, and other skincare formulations.
Methyl Gluceth-20 is versatility and compatibility with other ingredients make it a popular choice for formulators.

Methyl Gluceth-20, are subject to regulations to ensure their safety and efficacy.
Regulatory bodies in different regions may have specific guidelines and restrictions on the use of cosmetic ingredients, and formulators must adhere to these regulations when creating products for the market.
Methyl Gluceth-20 is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.

Methyl Gluceth-20 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-20 is low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.
Methyl Gluceth-20 is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.

Methyl Gluceth-20 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-20 is low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.

Methyl Gluceth-20 is a naturally-derived, mild ingredient that delivers moisture to the skin while reducing the tacky feel normally associated with the ingredients typically used in moisturizing skin creams.
Methyl Gluceth-20 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-20 is low irritation potential makes it ideal for use in both rinse off and leave on skin care systems such as lotions, creams, and body cleansing formulations.

Methyl Gluceth-20 is an ethoxylated methyl glucose ether and is 100% active.
Methyl Gluceth-20 is low irritation potential makes it ideal for sensitive skin formulations.

In addition, Methyl Gluceth-20 helps prevent soap bars from cracking and acts as a process aid in soap bar extrusion.
Methyl Gluceth-20 is a natural component of the stratum corneum layers of skin that binds water and hydrates skin.
Methyl Gluceth-20 is a component of what are called “natural moisturizing factors” or NMF.

Methyl Gluceth-20 moisturizers, including Methyl Gluceth-20 and -20, are naturally derived water-soluble emollients, humectants and moisturizers.
Methyl Gluceth-20 is a corn-based naturally derived emollient noted for its safety and mildness that imparts a smooth and silky feel on the skin.
Methyl Gluceth-20s also improve the richness of shampoos and enhance the foaming properties of cleansers.

Methyl Gluceth-20 is considered a special moisturizing agent used particularly for its moisture retentive qualities and as a surfactant in skin creams and other cosmetics to open pores and follicles.
Methyl Gluceth-20s are frequently used in creams and cosmetics along with other ingredients to improve skin hydration.
Other natural moisturizing factors include amino acids, carboxylic pyrrolidone acid, lactic acid, urea, and mineral ions.

The natural moisturizing factors contained in the corneocytes of skin are formed during epidermal skin cell differentiation and may represent up to ten percent of corneocyte cell mass.
The binding of water to natural moisturizing factors in skin is considered by experts to be the static aspect of cutaneous hydration.
Methyl Gluceth-20 is a water-soluble liquid moisturizer and emollient.

As an ingredient in cosmetic formulations, Methyl Gluceth-20 imparts a smooth and gentle skin feel.
Due to its exceptional water retention properties, Methyl Gluceth-20 finds uses in lotions, creams, after-shave products, bar soaps, bath products, hair wave products and cleansing products.
Methyl Gluceth-20 is a naturally-derived, multi-functional, mild ingredient that delivers a light, satin-like emollient feel in moisturizing systems.

This can contribute to keeping the skin hydrated and may be particularly beneficial in moisturizing formulations.
As an emollient, Methyl Gluceth-20 can contribute to the smoothness and softness of the skin by forming a protective barrier.
Methyl Gluceth-20 has a smooth, silky feel and can reduce the tackiness of other humectants.

Uses:
Methyl Gluceth-20 is use can contribute to achieving the desired viscosity and spreadability in various formulations.
The humectant properties of Methyl Gluceth-20 can help regulate moisture content on the skin's surface, making it suitable for products designed to provide hydration in different climates and environmental conditions.
Methyl Gluceth-20 is sometimes included in hair care formulations such as conditioners and shampoos to provide conditioning and a smooth texture.

Methyl Gluceth-20 is water-soluble nature makes it suitable for rinse-off hair care products.
Methyl Gluceth-20 can be part of serum formulations, contributing to the overall texture and spreadability of the product.
Methyl Gluceth-20 is moisturizing properties can enhance the serum's ability to hydrate the skin.

Methyl Gluceth-20 is included in sunscreen formulations.
Methyl Gluceth-20 is emollient properties can contribute to the even application of the sunscreen, and its humectant properties can help maintain skin hydration.
Due to its stabilizing properties, Methyl Gluceth-20 can be used to enhance the stability of various formulations, preventing ingredient separation or changes in texture over time.

Methyl Gluceth-20 may be found in certain makeup formulations, such as foundations, concealers, and tinted moisturizers.
Methyl Gluceth-20 is emollient properties can contribute to a smoother application, while its humectant properties help maintain skin hydration.

In skincare masks, particularly hydrating masks, Methyl Gluceth-20 can play a role in providing a moisture boost to the skin.
Methyl Gluceth-20 contributes to the overall texture and feel of the mask.
Due to its moisturizing and skin-conditioning properties, Methyl Gluceth-20 can be included in pre-shave and after-shave products.

Methyl Gluceth-20 helps prepare the skin for shaving and provides post-shave hydration.
Methyl Gluceth-20's mild and hydrating properties make it suitable for use in baby care products such as baby lotions, creams, and mild cleansers.
Methyl Gluceth-20 is water-soluble nature and moisturizing properties make Methyl Gluceth-20 suitable for inclusion in some sunscreens and sun care products.

Methyl Gluceth-20 can enhance the application experience and provide additional skin conditioning.
Formulators often use Methyl Gluceth-20 to enhance the overall aesthetics of a product.
This includes factors such as the color, texture, and appearance, contributing to a visually appealing final product.

The inclusion of Methyl Gluceth-20 in formulations can aid in the delivery of other active ingredients into the skin.
This can be particularly important in products designed to target specific skin concerns.
Due to its mild and hydrating properties, products containing Methyl Gluceth-20 may be suitable for post-procedure skincare, providing a soothing and moisturizing effect.

Dermatologists may recommend products containing Methyl Gluceth-20 for individuals with specific skin conditions or sensitivities, owing to its generally gentle nature.
Methyl Gluceth-20 is widely accepted in the cosmetics industry globally, making it a common ingredient in products available in various markets.
Individuals interested in DIY skincare formulations may choose to incorporate Methyl Gluceth-20 for its emollient and humectant properties, adding it to their creations to achieve desired skincare benefits.

Methyl Gluceth-20 might be included in anti-aging formulations to provide hydration and improve the overall feel of the product on the skin.
Methyl Gluceth-20 is non-greasy feel makes it suitable for inclusion in products designed for daily use.
Given its generally mild nature, Methyl Gluceth-20 may be used in products designed for individuals with sensitive skin.

Methyl Gluceth-20 can contribute to the gentleness of formulations.
In some formulations for intimate care products, Methyl Gluceth-20 can contribute to a comfortable and moisturizing experience.
Methyl Gluceth-20 is surfactant properties make Methyl Gluceth-20 suitable for inclusion in body washes and shower gels, contributing to effective cleansing and a pleasant skin feel.

Methyl Gluceth-20 is often included in multi-functional products that aim to provide various skincare benefits in one formulation, such as combining hydration with other active ingredients.
Methyl Gluceth-20 is often included in formulations with active ingredients, such as antioxidants, vitamins, or peptides.
Methyl Gluceth-20 is compatibility with these actives allows for the creation of comprehensive skincare products that address multiple concerns.

Methyl Gluceth-20 can contribute to stabilizing fragrances, helping to maintain the scent integrity of the product over time.
Because of its lightweight and non-greasy feel, products containing Methyl Gluceth-20 are often suitable for layering in a skincare routine.
Individuals can comfortably apply multiple products without feeling heavy or sticky.

Methyl Gluceth-20 can contribute to the overall sensorial experience of a product.
Methyl Gluceth-20 is inclusion can result in formulations that feel pleasant on the skin, encouraging regular use.
Methyl Gluceth-20 is compatible with a wide range of cosmetic ingredients, including active compounds and other moisturizing agents.

This compatibility allows formulators to create complex formulations that address multiple skincare needs.
As a derivative of glucose and methyl alcohol, Methyl Gluceth-20 is generally considered to be more biodegradable compared to some synthetic alternatives.
This aspect aligns with growing consumer preferences for environmentally friendly cosmetic ingredients.

Cosmetic formulators consider Methyl Gluceth-20's compliance with regulations in various regions.
Meeting regulatory standards ensures that products containing this ingredient can be marketed globally.
Use High levels of Methyl Gluceth-20 of more than 2% can cause a sensation of skin heat.

In some users But it doesn't cause any allergy or irritation.
Methyl Gluceth-20 is a skin humectant and a preservative.
This is the polyethylene glycol ether of Methyl Gluceth-20.

Methyl Gluceth-20 can be used added to formulas as is.
Methyl Gluceth-20 is often included in moisturizing products such as creams, lotions, and serums.
Methyl Gluceth-20 is humectant properties help attract and retain moisture, promoting hydration and preventing dryness.

This ingredient can be found in facial cleansers and body washes.
Methyl Gluceth-20 is surfactant properties contribute to the even distribution of the product on the skin, and its emollient properties can provide a smooth and gentle cleansing experience.
Methyl Gluceth-20 is used in toners to add hydration and improve the skin feel.

Toners with this ingredient may help balance the skin's moisture levels after cleansing.
Formulators often choose Methyl Gluceth-20 for its versatility in adjusting the consistency and texture of cosmetic products.

Safety Profile:
Methyl Gluceth-20's recommended to perform a patch test before using a product with Methyl Gluceth-20, especially for those with sensitive skin.
Avoid direct contact with the eyes, as some cosmetic ingredients, including Methyl Gluceth-20, may cause irritation.
Individuals with known allergies to specific components or chemical compounds should carefully review product labels for potential allergens.

Products containing Methyl Gluceth-20 should adhere to regulatory standards set by relevant authorities.
Cosmetic formulations must meet safety guidelines and ingredient restrictions.
While Methyl Gluceth-20 is known for its mild nature, some individuals may be sensitive or allergic to certain cosmetic ingredients.

The overall safety of a product depends on its complete formulation.
Methyl Gluceth-20's essential to consider the concentration of Methyl Gluceth-20 and its interactions with other ingredients in the product.
While Methyl Gluceth-20 is considered biodegradable, the environmental impact of cosmetic ingredients is an evolving area of concern.

METHYL GLUCOSE DIOLEATE
METHYL GLUCOSE ISOSTEARATE, Nom INCI : METHYL GLUCOSE ISOSTEARATE. Ses fonctions (INCI). Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile). Agent d'entretien de la peau : Maintient la peau en bon état
Methyl Glucose Isostearate
METHYL GLUCOSE ISOSTEARATE METHYL GLUCOSE ISOSTEARATE is classified as : Emulsifying Skin conditioning COSING REF No: 35294 Chem/IUPAC Name: D-Glucopyranoside, methyl, isooctadecanoate
Methyl Glucose Sesquistearate
METHYL GLUCOSE SESQUISTEARATE is classified as : Emollient; Emulsifying; Skin conditioning; CAS Number 68936-95-8; EINECS 273-049-0; Chem/IUPAC Name: D-Glucopyranoside, methyl, octadecanoate (2:3). PEG 20 Methyl Glucose Sesquistearate is used in beauty products and cosmetics as both an emollient and surfactant. It is the polyethylene glycol ether of the mono and diesters of Methyl Glucose and Stearic Acid, and is minimally absorbed by skin because of its low molecular weight, according to research. Functions: PEG 20 Methyl Glucose Sesquistearate is used in beauty products and cosmetics as both an emollient and surfactant. It is the polyethylene glycol ether of the mono and diesters of Methyl Glucose and Stearic Acid, and is minimally absorbed by skin because of its low molecular weight, according to research. Despite the many fears regarding PEGs, they are seen as an ingredient in a large number of products because of their diverse properties. In a study published in the Toxicology journal in 2005, entitled "Safety assessment on polyethylene glycols (PEGs) and their derivatives as used in cosmetic products," it was concluded that: "Taking into consideration all available information from related compounds, as well as the mode and mechanism of action, no safety concern with regard to these endpoints could be identified. Based on the available data it is therefore concluded that PEGs of a wide molecular weight range (200 to over 10,000), their ethers (laureths, ceteths, ceteareths, steareths, and oleths), and fatty acid esters (laurates, dilaurates, stearates, distearates) are safe for use in cosmetics." PEGs are not considered to be irritants or sensitizers, and are CIR and FDA approved for use, but not on broken skin. A mild, water-loving emulsifier that's safe for sensitive skin or eye-care formulations. It helps to create low viscosity oil-in-water emulsions, ideal for milks, serums, and sprayable formulations. It's derived from natural sources and gives a light, satiny afterfeel.
Methyl heptine carbonate
methyl hexahydrophthalic anhydride (MHHPA); exahydromethylphthalic anhydride; methyl-1,2-cyclohexanedicarboxylic anhydride mixture of isomers; 1,3-Isobenzofurandione, hexahydromethyl-; METHYLAEXAHYDROPHTHALIC ANHYDRIDE(MIXTURE OF 3-AND 4-); 1. Methyl Hexahydrophthalic Anhydride (MHHPA); 3-Isobenzofurandione, hexahydromethyl-1; hexahydromethyl-3-isobenzofurandione; Methylcyclohexane-1,2-dicarboxylic anhydride; Methylhexahydrophthalic anhydride; 1-Methylhexahydrophthalic Anhydride CAS NO:25550-51-0
METHYL ISOBUTYL CARBINOL
DESCRIPTION:
Methyl Isobutyl Carbinol is Alcohol with a low evaporation rate, good solubility in oils, waxes and natural resins.
Methyl Isobutyl Carbinol’ s main application is in mining as a foaming agent, given its high degree of metal recovery, especially precious metals.


CAS NUMBER: 108-11-2
EC-No. : 203-551-7
MOLECULAR FORMULA: C6H14O
MOLECULAR WEIGHT:102.17

Methyl isobutyl carbinol (MIBC) is a liquid derivative of acetone.
Methyl isobutyl carbinol has limited solubility in water but is miscible with most organic solvents.

Methyl isobutyl carbinol is an organic chemical compound commonly used as a “frother” in mineral flotation and in the production of lubricant oil additives.
Frothing, also known as froth flotation, is the process of selectively separating hydrophobic valuable minerals from hydrophilic waste gangue.
In its simplest form, froth flotation is a method whereby minerals can be “skimmed” from the surface of “slurry” that is “foamed” with the assistance of specific chemicals, water and air bubbles.

Methyl isobutyl carbinol is a colorless chemical compound primarily used in lube oil applications (as a chemical intermediate in manufacture of zinc dialkyldithiophosphate) and mining operations (as a flotation frother).
Methyl isobutyl carbinol is also so used in smaller volumes as a coating solvent (in nitrocellulose and hot spray lacquers).


USES OF METHYL ISOBUTYL CARBINOL:
Methyl isobutyl carbinol is a latent solvent for coating films, adjusting the cure rate, reducing viscosity and improving flowability and flare.
The product is slightly soluble in water and miscible with most organic solvents.
Methyl isobutyl carbinol is a colourless stable liquid with a slight scent of alcohol.


AREAS OF APPLICATION:
• Foamer in mining
• Solvent for nitrocellulose and methylcellulose lacquers, oil, ester gums, natural resins, phenols and waxes
• Extractant in essential oils for flavours and fragrances
• Diluent for hydraulic oil
• Process solvents for soap



METHYL ISOBUTYL CARBINOL (MIBC) FOR FROTHING SOLUTIONS
Froth flotation is used in the mining industry to selectively separate valuable hydrophobic minerals from hydrophilic waste gangue.
This technique is especially useful for separating a wide range of sulfides, carbonates, and oxides prior to further refinement.

Methyl isobutyl carbinol is used as a frother in the flotation process.
Methyl isobutyl carbinol absorbs at the water-air interface, aids in the production of bubbles, and stabilizes the flotation froths.
Two major types of frothers in commercial use today are short chain aliphatic alcohols and polyglycols.


SAFETY INFORMATION ABOUT METHYL ISOBUTYL CARBINOL:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product








CHEMICAL AND PHYSICAL PROPERTIES OF METHYL ISOBUTYL CARBINOL:
Chemical Formula: C6H14O
Flash Point: 106°F (USCG, 1999)
Lower Explosive Limit (LEL): 1 % (USCG, 1999)
Upper Explosive Limit (UEL): 5.5 % (USCG, 1999)
Autoignition Temperature: data unavailable
Melting Point: less than -130°F (USCG, 1999)
Vapor Pressure: 3 mmHg (NIOSH, 2022)
Vapor Density (Relative to Air): data unavailable
Specific Gravity: 0.807 at 68°F (USCG, 1999)
Boiling Point: 269.2°F at 760 mmHg (USCG, 1999)
Molecular Weight: 102.18 (USCG, 1999)
Water Solubility: 2 % (NIOSH, 2022)
Appearance : Liquid.
Colour : clear
Odour : sweet
Boiling point/boiling range : 130 - 133 °C
Flash point : 41 °C
Method: IP 170
Evaporation rate : 0,3
Method: ASTM D 3539, nBuAc=1
Upper explosion limit : upper flammability limit 5,5 %(V)
Lower explosion limit : lower flammability limit 1 %(V)
Vapour pressure : 420 Pa (20 °C)
Relative vapour density : 3,5
Relative density : 0,81 (20 °C)
Density : 806 - 808 kg/m3 (20 °C)
Method: ASTM D4052
Solubility(ies)
Water solubility : 16 g/l (20 °C)
Partition coefficient: noctanol/water
log Pow: < 3
Auto-ignition temperature : 305 °C
Method: ASTM E-659
Viscosity, dynamic : 5,2 mPa.s (20 °C) Molecular Weight 102.2 g/mol
Empirical Formula C6H14O
Appearance Colorless Liquid
Freezing Point -90°C (-130°F)
Flash Point – Closed Cup 40.5°C (105°F)
Boiling Point @ 760mmHg 131.7°C (269.1°F)
Autoignition Temperature 305°C
Density @ 20°C 0.81 kg/l
6.76 lb/gal
Vapor Pressure @ 20°C 0.42 kPa
Evaporation Rate (nBuAc = 1) 0.28
Solubility @ 20°C
(in Water)
(Water in)
1.6% m/m
6.3% m/m
Refractive Index @ 25°C 1.410
Viscosity @ 20°C 5.2 cP
Surface Tension @ 20°C 23 dynes/cm
Lower Flammability in Air 1.0% v/v
Upper Flammability in Air 5.5% v/v
Specific Heat @ 20°C 2.4 kJ/kg/°C
Conductivity @ 20°C 0.3 μS/m
Dielectric Constant @ 20°C 10.4
Odor Threshold 1.1 ppm
Heat of Vaporization @ normal
boiling point
413 kJ/kg
Heat of Combustion @ 25°C 36000 kJ/kg





SYNONYMS OF METHYL ISOBUTYL CARBINOL:
1,3-DIMETHYL-1-BUTANOL
DL-METHYLISOBUTYLCARBINOL
ISOBUTYL METHYLMETHANOL
ISOBUTYLMETHYLCARBINOL
ISOBUTYLMETHYLMETHANOL
M.I.B.C.
MAA
MAOH
METHYL AMYL ALCOHOL
METHYL ISOBUTYL CARBINOL
4-METHYL-2-AMYL ALCOHOL
(.+-.)-4-METHYL-2-PENTANOL
4-METHYL-2-PENTANOL
4-METHYL-2-PENTYL ALCOHOL
2-METHYL-4-PENTANOL
METHYLAMYL ALCOHOL
METHYLISOBUTYLCARBINOL
MIBC
MIC
3-MIC



METHYL ISOBUTYL KETONE
METHYL ISOBUTYL KETONE Methyl isobutyl ketone Methyl isobutyl ketone Skeletal formula of methyl isobutyl ketone Ball-and-stick model of the methyl isobutyl ketone molecule Names Preferred IUPAC name 4-Methylpentan-2-one Other names 4-Methyl-2-pentanone, Isopropylacetone, Hexone, Isobutyl methyl ketone, 2-Methylpropyl methyl ketone, 4-Methyl-2-oxopentane, MIK, Isobutylmethyl ketone, MIBK, Isohexanone Identifiers CAS Number 108-10-1 check 3D model (JSmol) Interactive image ChemSpider 7621 ☒ ECHA InfoCard 100.003.228 EC Number 203-550-1 KEGG C19263 check PubChem CID 7909 RTECS number SA9275000 UNII U5T7B88CNP ☒ CompTox Dashboard (EPA) DTXSID5021889 Edit this at Wikidata InChI[show] SMILES[show] Properties Chemical formula C6H12O Molar mass 100.16 g/mol Appearance colorless liquid Odor pleasant[1] Density 0.802 g/mL, liquid Melting point −84.7 °C (−120.5 °F; 188.5 K) Boiling point 117 to 118 °C (243 to 244 °F; 390 to 391 K) Solubility in water 1.91 g/100 mL (20 °C) Vapor pressure 16 mmHg (20 °C)[1] Magnetic susceptibility (χ) -70.05·10−6 cm3/mol Refractive index (nD) 1.3958 Viscosity 0.58 cP at 20.0 °C Structure Dipole moment 2.8 D Hazards EU classification (DSD) (outdated) Flammable (F) Harmful (Xn) R-phrases (outdated) R11, R20, R36/37, R66 S-phrases (outdated) (S2), S9, S16, S29 NFPA 704 (fire diamond) NFPA 704 four-colored diamond 32 Flash point 14 °C (57 °F; 287 K) Autoignition temperature 449 °C (840 °F; 722 K) Explosive limits 1.2–8.0% (93 °C)[1] NIOSH (US health exposure limits): PEL (Permissible) TWA 100 ppm (410 mg/m3)[1] REL (Recommended) TWA 50 ppm (205 mg/m3) ST 75 ppm (300 mg/m3)[1] IDLH (Immediate danger) 500 ppm[1] Related compounds Related ketones Methyl isopropyl ketone 2-Pentanone Diisobutyl ketone Related compounds 2-Methylpentan-4-ol Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ☒ verify (what is check☒ ?) Infobox references Methyl isobutyl ketone (MIBK) is the organic compound with the formula (CH3)2CHCH2C(O)CH3. This colourless liquid, a ketone, is used as a solvent for gums, resins, paints, varnishes, lacquers, and nitrocellulose.[2] Production Methyl isobutyl ketone is made from acetone via a three-step process. Firstly acetone undergoes an aldol reaction to give diacetone alcohol, which readily dehydrates to give mesityl oxide. Mesityl oxide can then be hydrogenated to give MIBK: Synthesis of Methyl isobutyl ketone from acetone Industrially, these three steps are combined. Acetone is treated with a strong acidic, palladium-doped cation exchange resin under medium pressure of hydrogen.[3] Several million kilograms are produced annually.[4] In 2003, the industrial production capacity for Methyl isobutyl ketone in the United States was 88,000 tons.[5] Uses Methyl isobutyl ketone tank car in Europe. Methyl isobutyl ketone is used as a solvent for nitrocellulose, lacquers, and certain polymers and resins.[4] Precursor to 6PPD Another major use is as a precursor to N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylene diamine (6PPD), an antiozonant used in tires. 6PPD is prepared by reductive coupling of Methyl isobutyl ketone with 4-aminodiphenylamine.[6] Solvent and niche applications Unlike the other common ketone solvents, acetone and MEK, Methyl isobutyl ketone has quite low solubility in water, making it useful for liquid-liquid extraction. It has a similar polarity to ethyl acetate, but greater stability towards aqueous acid and base. It can be used to extract gold, silver and other precious metals from cyanide solutions, such as those found at gold mines, to determine the levels of those dissolved metals. Diisobutyl ketone (DIBK), a related lipophilic ketone, is also used for this purpose. Methyl isobutyl ketone is also used as a denaturing agent for denatured alcohol. When mixed with water or isopropyl alcohol Methyl isobutyl ketone serves as a developer for PMMA electron beam lithography resist. Methyl isobutyl ketone is used as a solvent for CS in the preparation of the CS spray used currently by British police forces. Molecular Weight of Methyl isobutyl ketone: 100.16 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) XLogP3 1.3 Computed by XLogP3 3.0 (PubChem release 2019.06.18) Hydrogen Bond Donor Count of Methyl isobutyl ketone: 0 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Hydrogen Bond Acceptor Count of Methyl isobutyl ketone: 1 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Rotatable Bond Count of Methyl isobutyl ketone: 2 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Exact Mass of Methyl isobutyl ketone: 100.088815 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Monoisotopic Mass of Methyl isobutyl ketone: 100.088815 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Topological Polar Surface Area of Methyl isobutyl ketone: 17.1 Ų Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Heavy Atom Count of Methyl isobutyl ketone: 7 Computed by PubChem Formal Charge of Methyl isobutyl ketone: 0 Computed by PubChem Complexity of Methyl isobutyl ketone: 64.6 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Isotope Atom Count of Methyl isobutyl ketone: 0 Computed by PubChem Defined Atom Stereocenter Count of Methyl isobutyl ketone: 0 Computed by PubChem Undefined Atom Stereocenter Count of Methyl isobutyl ketone: 0 Computed by PubChem Defined Bond Stereocenter Count of Methyl isobutyl ketone: 0 Computed by PubChem Undefined Bond Stereocenter Count of Methyl isobutyl ketone: 0 Computed by PubChem Covalently-Bonded Unit Count of Methyl isobutyl ketone: 1 Computed by PubChem Compound of Methyl isobutyl ketone Is Canonicalized Yes Methyl Isobutyl Ketone (MIBK) - part of our Ketones range of high purity oxygenated chemical solvents. Methyl isobutyl ketone is an active solvent with excellent dissolving characteristics, a high tolerance to other hydrocarbon diluents and a medium evaporation rate. Ketones are strong polar solvents thanks to their carbonyl functional group. Their high solvency and excellent stability make them a solvent of choice for coatings, adhesives, inks and cleaning applications. Methyl isobutyl ketone is a ‘true’ or active solvent due to its compatibility with a variety of organic components and its ability to dissolve them on its own without the need for an alcohol, which can help to simplify system formulations. It also has the ability to combine with lower-cost hydrocarbon solvents in solvent blends. Methyl isobutyl ketone is a colourless liquid with a stable chemical nature and a medium boiling range. It is able to dissolve cellulose esters, vinyl polymers and copolymers, and most natural and synthetic resins and is also partially miscible in water. Its relatively low density combined with strong solvency assists coatings formulators in producing high-quality, high-solids formulations that are also able to comply with VOC regulations. Because of its high solvent strength, less solvent is required to dissolve a resin and in applications where the solvent evaporates to the atmosphere during use, lower levels of VOC emissions are produced. Hazard Summary Methyl isobutyl ketone is used as a solvent for gums, resins, paints, varnishes, lacquers, and nitrocellulose. Acute (short-term) exposure to methyl isobutyl ketone may irritate the eyes and mucous membranes, and cause weakness, headache, nausea, lightheadedness, vomiting, dizziness, incoordination, narcosis in humans. Chronic (long-term) occupational exposure to methyl isobutyl ketone has been observed to cause nausea, headache, burning in the eyes, weakness, insomnia, intestinal pain, and slight enlargement of the liver in humans. Lethargy and kidney and liver effects have been observed in rats and mice chronically exposed by gavage (experimentally placing the chemical in the stomach), ingestion, and inhalation. EPA has classified methyl isobutyl ketone as a Group D, not classifiable as to human carcinogenicity. Uses Methyl isobutyl ketone is used as a solvent for gums, resins, paints, varnishes, lacquers, and nitrocellulose, as an alcohol denaturant, in the extraction of rare metals, and as a synthetic flavoring adjuvant. (1,3,9) Sources and Potential Exposure Occupational exposure may occur in the workplace by the inhalation of vapors and by skin and eye contact. (1) The most probable routes of exposure to methyl isobutyl ketone by the general population are by inhalation and dermal contact during the use of consumer products that contain this compound. (1) Methyl isobutyl ketone may be released to the environment in effluent and emissions from its manufacture and use, in exhaust gas from vehicles, and from land disposal and ocean dumping of waste that contains this compound. Since methyl isobutyl ketone is a solvent and denaturant with a wide variety of applications, a large number of industries could potentially release this compound. Some segments of the population may be exposed by the inhalation of contaminated air or by the ingestion of contaminated drinking water. Methyl isobutyl ketone is used as a chemical intermediate, a solvent for manufacturing paints, rubbers, pharmaceuticals, other chemicals, and industrial cleaners. It is used in the semiconductor industry. Methyl isobutyl ketone is very efficient at dissolving resins used in paints, inks, lacquers, and other types of surface coatings. Synonyms for Methyl isobutyl ketone are hexone, isobutyl methyl ketone, and isohexanone. Methyl isobutyl ketone is a Food and Drug Administration (FDA)-approved indirect food additive for adhesives, paper and paperboard, and polymers.
METHYL ISOSTEARATE
Methylpentanol; MIBC; sec-Hexyl Alcohol; MAOH; 2-Methyl-4-pentanol; 4-methyl-2-pentanol; 4-Methylpentan-2-ol; Isobutylmethyl Carbinol; Methyl-2-pentanol; Methylamyl alcohol; Isobutylmethyl Methanol CAS NO:108-11-2
Methyl isobutyl carbinol (MIBC)
Methylpentanol; MIBC; sec-Hexyl Alcohol; MAOH; 2-Methyl-4-pentanol; 4-methyl-2-pentanol; 4-Methylpentan-2-ol; Isobutylmethyl Carbinol; Methyl-2-pentanol; Methylamyl alcohol; Isobutylmethyl Methanol CAS NO:108-11-2
Methyl isobutyl ketone ( MIBK) Méthyl isobutyl cétone
METHYL LACTATE, N° CAS : 27871-49-4 / 547-64-8. Nom INCI : METHYL LACTATE. Nom chimique : 2-Hydroxy-propanoic acid methyl ester, (S)- / 2-hydroxy-propanoic acid methyl ester, N° EINECS/ELINCS : 248-704-9 / 208-930-0. Ses fonctions (INCI). Solvant : Dissout d'autres substances. Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques. Agent arômatisant : Donne un arôme au produit cosmétique
METHYL LACTATE
4,7-Methanoisobenzofuran-1,3-dione, 3a,4,7,7a-tetrahydromethyl-; 5-Norbornene-2,3-dicarboxylic anhydride, methyl-; endo-Methylenemethyltetrahydrophthalic anhydride; Epicure NMA; Hardener HY906; HSDB 6093; Kayahard MCD; MEA 610; Methendic anhydride; Methyl-1,2,3,6-tetrahydro-3,6-endomethylenephthalic anhydride; Methyl-5-norbornene-2,3-dicarboxylic anhydride; Methyl-tetrahydro-3,6-endomethylenephthalic anhydride; Methylbicyclo(2.2.1)heptene-2,3-dicarboxylic anhydride; Methylbicyclo(2.2.1)heptene-2,3-dicarboxylic anhydride isomers; Methylendic anhydride; Methylnorbornene-2,3-dicarboxylic anhydride CAS NO:25134-21-8
Methyl methacrylate Crosspolymer
METHYL METHACRYLATE CROSSPOLYMER;methyl methacrylate/ ethylene glycol dimethacrylate copol.;Methyl methacrylate-Ethylene glycol dimethacrylate copolymer;POLY(METHYL METHACRYLATE-CO-ETHYLENE GLY COL DIMETHACRYLATE), 8 MICRON;POLY(METHYL METHACRYLATE-CO-ETHYLENE GLY COL DIMETHACRYLATE), 50 MICRON;POLY(METHYL METHACRYLATE-CO-ETHYLENE GLY COL DIMETHACRYLATE), 20 MICRON;Poly(methyl methacrylate-co-ethylene glycol dimethacrylate) 50 mum particle size;Diaion? HP2MGL, synthetic adsorbent resin, Highly porous type, 10g/L on polymethacrylate;2-Propenoic acid, 2-methyl-, 1,2-ethanediyl ester, polymer with methyl 2-methyl-2-propenoate CAS Number 25777-71-3
METHYL NICOTINATE
METHYL OLEATE; (Z)-9-octadecenoic acid methyl ester; Methyl 9-octadecenoate; Methyl cis-9-Octadecenoate; Oleic acid Methyl ester; cas no: 112-62-9
METHYL OLEATE
Methyl Oleate IUPAC Name methyl (Z)-octadec-9-enoate Methyl Oleate InChI 1S/C19H36O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19(20)21-2/h10-11H,3-9,12-18H2,1-2H3/b11-10- Methyl Oleate InChI Key QYDYPVFESGNLHU-KHPPLWFESA-N Methyl Oleate Canonical SMILES CCCCCCCCC=CCCCCCCCC(=O)OC Methyl Oleate Isomeric SMILES CCCCCCCC/C=C\CCCCCCCC(=O)OC Methyl Oleate Molecular Formula C19H36O2 Methyl Oleate CAS 112-62-9 Methyl Oleate Deprecated CAS 139152-82-2, 228858-36-4 Methyl Oleate European Community (EC) Number 203-992-5 Methyl Oleate NSC Number 406282 Methyl Oleate UNII 39736AJ06R Methyl Oleate DSSTox Substance ID DTXSID5025811 Methyl Oleate Physical Description Oleic acid methyl ester is a clear to amber liquid. Insoluble in water. Methyl Oleate Color/Form Colorless to amber clear liquid Methyl Oleate Odor Faint fatty odor Methyl Oleate Boiling Point 425.3 °F at 20 mm Hg Methyl Oleate Melting Point -3.8 °F Methyl Oleate Solubility Insoluble Methyl Oleate Density 0.8739 Methyl Oleate Vapor Pressure 6.29e-06 mmHg Methyl Oleate LogP 7.45 Methyl Oleate Decomposition When heated to decomposition it emits acrid smoke and irritating fumes. Methyl Oleate Viscosity Viscosity coefficients = 4.88, 2.62, and 1.64 cP at 30, 60, and 90 °C, respectively Methyl Oleate Heat of Combustion At constant volume, delta Ec = -2837.3 kcal/mol at 25 °C Methyl Oleate Heat of Vaporization 20.17 kcal/mol at 1 torr Methyl Oleate Surface Tension 31.3 dyne/cm at 25 °C; 25.4 dyne/cm at 100 °C; 19.1 dyne/cm at 180 °C Methyl Oleate Refractive Index MAX ABSORPTION (ALCOHOL): 230 NM (LOG E= 3.5); INDEX OF REFRACTION: 1.4522 AT 20 °C; SADTLER REFERENCE NUMBER: 917 (IR, PRISM) Methyl Oleate Molecular Weight 296.5 g/mol Methyl Oleate XLogP3-AA 7.6 Methyl Oleate Hydrogen Bond Donor Count 0 Methyl Oleate Hydrogen Bond Acceptor Count 2 Methyl Oleate Rotatable Bond Count 16 Methyl Oleate Exact Mass 296.27153 g/mol Methyl Oleate Monoisotopic Mass 296.27153 g/mol Methyl Oleate Topological Polar Surface Area 26.3 Ų Methyl Oleate Heavy Atom Count 21 Methyl Oleate Formal Charge 0 Methyl Oleate Complexity 246 Methyl Oleate Isotope Atom Count 0 Methyl Oleate Defined Atom Stereocenter Count 0 Methyl Oleate Undefined Atom Stereocenter Count 0 Methyl Oleate Defined Bond Stereocenter Count 1 Methyl Oleate Undefined Bond Stereocenter Count 0 Methyl Oleate Covalently-Bonded Unit Count 1 Methyl Oleate Compound Is Canonicalized Yes Methyl Oleate is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of oleic acid with methanol. It derives from an oleic acid.Methyl Oleate is exempted from the requirement of a tolerance when used as a surfacant in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops only.Methyl Oleate is exempted from the requirement of a tolerance when used as a surfacant in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops only.Methyl Oleate is an indirect food additive for use only as a component of adhesives.Methyl Oleate WAS TESTED FOR CARCINOGENICITY BY ORAL & SC ADMIN IN ST/A MICE OF BOTH SEXES, BUT A POSITIVE EFFECT COULD NOT BE ASSESSED.Methyl Oleate PROMOTED SKIN TUMOR FORMATION IN MICE. THE RELATION OF MOLECULAR CONFIGURATION & CARCINOGENICITY OF FATTY ACIDS IS DISCUSSED.GROWTH OF THE CRICKET, CRYLLODES SIGILLATUS, WAS SHOWN TO BE INHIBITED BY FATTY ACIDS & SOME FATTY ACID METHYL ESTERS. THE ROUTE OF ENTRY APPEARED TO BE THROUGH THE CUTICLE OF THE TARSI. Methyl Oleate SIGNIFICANTLY RETARDED GROWTH, & RESULTED IN LOWER SURVIVAL.Methyl Oleate was found to be negative when tested for mutagenicity using the Salmonella/microsome preincubation assay, using the standard protocol approved by the National Toxicology Program (NTP). Methyl Oleate was tested in as many as 5 Salmonella typhimurium strains (TA1535, TA1537, TA97, TA98, and TA100) in the presence and absence of rat and hamster liver S-9, at doses of 0.100, 0.333, 1.000, 3.333, and 10.000 mg/plate. The highest negative dose tested in any S. typhimurium strain was 10.000 mg/plate. Slight clearing of the background bacterial lawn occurred at the high dose in cultures without activation.Methyl Oleate's production and use as a synthetic intermediate may result in its release to the environment through various waste streams. If released to air, a vapor pressure of 6.3X10-6 mm Hg at 25 °C indicates Methyl Oleate will exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase Methyl Oleate will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 7.5 hours. Vapor-phase Methyl Oleate will also be degraded in the atmosphere by reaction with ozone; the half-life for this reaction is estimated to be 2.1 hours. Particulate-phase Methyl Oleate will be removed from the atmosphere by wet and dry deposition. If released to soil, Methyl Oleate is expected to have no mobility based upon an estimated Koc of 62,000. Volatilization from moist soil surfaces is expected to be an important fate process based upon an estimated Henry's Law constant of 0.014 atm-cu m/mole. However, adsorption to soil is expected to attenuate volatilization. Methyl Oleate is expected to rapidly biodegrade in aerobic soils as suggested by the rapid biodegradation of structurally similar long-chain fatty acid esters. If released into water, Methyl Oleate is expected to adsorb to suspended solids and sediment in the water column based upon the estimated Koc. Methyl Oleate is expected to rapidly biodegrade in aerobic waters as suggested by the rapid biodegradation of structurally similar long-chain fatty acid esters. Volatilization from water surfaces is expected to be an important fate process based upon this compound's estimated Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 5 hours and 7 days, respectively. However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column. The volatilization half-life from a model pond is estimated to be about 61 hours ignoring adsorption; when considering maximum adsorption the volatilization half-life increases to 18 months. An estimated BCF of 490 suggests the potential for bioconcentration in aquatic organisms is moderate. An estimated base-catalyzed second-order hydrolysis rate constant of 0.011 L/mole-sec corresponds to half-lives of 2 years and 74 days at pH values of 7 and 8, respectively. Occupational exposure to Methyl Oleate may occur through inhalation and dermal contact with this compound at workplaces where Methyl Oleate is produced or used. (SRC)Methyl Oleate's production and use as a synthetic intermediate may result in its release to the environment through various waste streams.TERRESTRIAL FATE: Based on a classification scheme, an estimated Koc value of 62,000(SRC), determined from a structure estimation method, indicates that Methyl Oleate is expected to be immobile in soil(SRC). Volatilization of Methyl Oleate from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 0.014 atm-cu m/mole(SRC), using a fragment constant estimation method. However, adsorption to soil is expected to attenuate volatilization(SRC). Methyl Oleate is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 6.3X10-6 mm Hg. Methyl Oleate is expected to rapidly biodegrade in aerobic soils as suggested by the rapid biodegradation of structurally similar long-chain fatty acid esters.Based on a classification scheme, an estimated Koc value of 62,000(SRC), determined from a structure estimation method, indicates that Methyl Oleate is expected to adsorb to suspended solids and sediment in water(SRC).Methyl Oleate is expected to rapidly biodegrade in aerobic soils as suggested by the rapid biodegradation of structurally similar long-chain fatty acid esters. An estimated base-catalyzed second-order hydrolysis rate constant of 0.011 L/mole-sec(9,SRC) corresponds to half-lives of 2 years and 70 days at pH values of 7 and 8, respectively(11).According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), Methyl Oleate, which has a vapor pressure of 6.3X10-6 mm Hg at 25 °C, will exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase Methyl Oleate is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 7.5 hours(SRC) from its estimated rate constant of 7.4X10-11 cu cm/molecule-sec at 25 °C. Vapor-phase Methyl Oleate is also degraded in the atmosphere by reaction with ozone(SRC); the half-life for this reaction in air is estimated to be 2.1 hours(SRC) from its estimated rate constant of 1.3X10-16 cu cm/molecule-sec at 25 °C. Particulate-phase Methyl Oleate may be removed from the air by wet and dry deposition(SRC).The rate constant for the vapor-phase reaction of Methyl Oleate with photochemically-produced hydroxyl radicals has been estimated as 7.4E-11 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method. This corresponds to an atmospheric half-life of about 7.5 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm. The rate constant for the vapor-phase reaction of Methyl Oleate with ozone has been estimated as 1.3X10-16 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method. This corresponds to an atmospheric half-life of about 2 hours at an atmospheric concentration of 7X10+11 ozone molecules per cu cm. A base-catalyzed second-order hydrolysis rate constant of 0.11 L/mole-sec(SRC) was estimated using a structure estimation method; this corresponds to half-lives of 2 years and 70 days at pH values of 7 and 8, respectively. The predicted near-surface half-life for the photosensitized oxidation of Methyl Oleate in near suface waters in the Southern US is 1100 hrs. Methyl Oleate is not expected to directly photolyze due to the lack of absorption in the environmental UV spectrum.An estimated BCF of 490 was calculated for Methyl Oleate(SRC) using a log Kow of 7.45 and a regression-derived equation. According to a classification scheme, the estimated BCF suggests the potential for bioconcentration in aquatic organisms is moderate.Using a structure estimation method based on molecular connectivity indices, the Koc for Methyl Oleate can be estimated to be about 62,000(SRC). According to a classification scheme, this estimated Koc value suggests that Methyl Oleate is expected to be immobile in soil.The Henry's Law constant for Methyl Oleate is estimated as 0.014 atm-cu m/mole(SRC) using a fragment constant estimation method. This Henry's Law constant indicates that Methyl Oleate is expected to volatilize rapidly from water surfaces. Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec) is estimated as approximately 5 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec) is estimated as approximately 7 days(SRC). The volatilization half-life from a model pond 2 m deep is estimated to be about 61 hours ignoring adsorption; when considering maximum adsorption the volatilization half-life increases to 18 months. Methyl Oleate's Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). Methyl Oleate is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 6.3X10-6 mm Hg.Methyl Oleate was detected in trace quantities in samples from the River Lee, in the UK.Methyl Oleate was identified in 3 of 3 New Jersey POTW effluents, date not provided, at a estimated concentration of 0.3-18 ppb. It was detected in 13 of 13 effluents samples from an olive oil production plant, Spain, at 520-77721 ug/l. It was qualitatively detected in the effluent of a pulp and paper mill in Finland.First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)If you spill this chemical, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with alcohol followed by washing with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should keep this material in a tightly-closed container under an inert atmosphere, and store it at refrigerated temperatures. Methyl oleate is exempted from the requirement of a tolerance when used as a surfacant in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops only.Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. RECOMMENDED GLOVE MATERIALS: Permeation data indicate that neoprene gloves may provide protection to contact with this compound. Neoprene over latex gloves is recommended. However, if this chemical makes direct contact with your gloves, or if a tear, puncture or hole develops, remove them at once. Esters, such as OLEIC ACID METHYL ESTER, react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.Methyl oleate is exempted from the requirement of a tolerance when used as a surfacant in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops only.0.05 ML OF 10% EMULSION OF OLEIC ACID IN NACL SOLN OR 0.05 ML OF 10% SOLN OF SODIUM OLEATE ADJUSTED WITH HCL TO PH 7.2 INJECTED INTO CORNEAS OF RABBITS CAUSED EYES TO BECOME INFLAMED WITHIN FEW HR & TO DEVELOP CORNEAL ABSCESS WITHIN FEW DAYS. ... METHYL OLEATE ALSO PRODUCED NECROSIS & LIPOGENESIS WHEN TESTED IN SAME WAY.Methyl oleate was found to be negative when tested for mutagenicity using the Salmonella/microsome preincubation assay, using the standard protocol approved by the National Toxicology Program (NTP). Methyl oleate was tested in as many as 5 Salmonella typhimurium strains (TA1535, TA1537, TA97, TA98, and TA100) in the presence and absence of rat and hamster liver S-9, at doses of 0.100, 0.333, 1.000, 3.333, and 10.000 mg/plate. The highest negative dose tested in any S. typhimurium strain was 10.000 mg/plate. Slight clearing of the background bacterial lawn occurred at the high dose in cultures without activation.Methyl oleate's production and use as a synthetic intermediate may result in its release to the environment through various waste streams. If released to air, a vapor pressure of 6.3X10-6 mm Hg at 25 °C indicates methyl oleate will exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase methyl oleate will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 7.5 hours. Vapor-phase methyl oleate will also be degraded in the atmosphere by reaction with ozone; the half-life for this reaction is estimated to be 2.1 hours. Particulate-phase methyl oleate will be removed from the atmosphere by wet and dry deposition. If released to soil, methyl oleate is expected to have no mobility based upon an estimated Koc of 62,000. Volatilization from moist soil surfaces is expected to be an important fate process based upon an estimated Henry's Law constant of 0.014 atm-cu m/mole. However, adsorption to soil is expected to attenuate volatilization. Methyl oleate is expected to rapidly biodegrade in aerobic soils as suggested by the rapid biodegradation of structurally similar long-chain fatty acid esters. If released into water, methyl oleate is expected to adsorb to suspended solids and sediment in the water column based upon the estimated Koc. Methyl oleate is expected to rapidly biodegrade in aerobic waters as suggested by the rapid biodegradation of structurally similar long-chain fatty acid esters. Volatilization from water surfaces is expected to be an important fate process based upon this compound's estimated Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 5 hours and 7 days, respectively. However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column. The volatilization half-life from a model pond is estimated to be about 61 hours ignoring adsorption; when considering maximum adsorption the volatilization half-life increases to 18 months. An estimated BCF of 490 suggests the potential for bioconcentration in aquatic organisms is moderate. An estimated base-catalyzed second-order hydrolysis rate constant of 0.011 L/mole-sec corresponds to half-lives of 2 years and 74 days at pH values of 7 and 8, respectively. Occupational exposure to methyl oleate may occur through inhalation and dermal contact with this compound at workplaces where methyl oleate is produced or used. Based on a classification scheme, an estimated Koc value of 62,000(SRC), determined from a structure estimation method, indicates that methyl oleate is expected to be immobile in soil(SRC). Volatilization of methyl oleate from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 0.014 atm-cu m/mole(SRC), using a fragment constant estimation method. However, adsorption to soil is expected to attenuate volatilization(SRC). Methyl oleate is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 6.3X10-6 mm Hg. Methyl oleate is expected to rapidly biodegrade in aerobic soils as suggested by the rapid biodegradation of structurally similar long-chain fatty acid esters.Based on a classification scheme, an estimated Koc value of 62,000(SRC), determined from a structure estimation method, indicates that methyl oleate is expected to adsorb to suspended solids and sediment in water(SRC). Volatilization from water surfaces is expected based upon an estimated Henry's Law constant of 0.014 atm-cu m/mole(SRC), developed using a fragment constant estimation method. Volatilization half-lives for a model river and model lake are 5 hours and 7 days, respectively(SRC), using an estimation method. However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column(SRC). The volatilization half-life from a model pond is estimated to be about 61 hours ignoring adsorption; when considering maximum adsorption the volatilization half-life increases to 18 months. According to a classification scheme, an estimated BCF of 490 from its log Kow of 7.45 and a regression-derived equation suggests the potential for bioconcentration in aquatic organisms is moderate. Methyl oleate is expected to rapidly biodegrade in aerobic soils as suggested by the rapid biodegradation of structurally similar long-chain fatty acid esters. An estimated base-catalyzed second-order hydrolysis rate constant of 0.011 L/mole-sec(SRC) corresponds to half-lives of 2 years and 70 days at pH values of 7 and 8, respectively.According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere, methyl oleate, which has a vapor pressure of 6.3X10-6 mm Hg at 25 °C, will exist in both the vapor and particulate phases in the ambient atmosphere. Vapor-phase methyl oleate is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 7.5 hours(SRC) from its estimated rate constant of 7.4X10-11 cu cm/molecule-sec at 25 °C. Vapor-phase methyl oleate is also degraded in the atmosphere by reaction with ozone(SRC); the half-life for this reaction in air is estimated to be 2.1 hours(SRC) from its estimated rate constant of 1.3X10-16 cu cm/molecule-sec at 25 °C. Particulate-phase methyl oleate may be removed from the air by wet and dry deposition(SRC).The rate constant for the vapor-phase reaction of methyl oleate with photochemically-produced hydroxyl radicals has been estimated as 7.4E-11 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method. This corresponds to an atmospheric half-life of about 7.5 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm. The rate constant for the vapor-phase reaction of methyl oleate with ozone has been estimated as 1.3X10-16 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method. This corresponds to an atmospheric half-life of about 2 hours at an atmospheric concentration of 7X10+11 ozone molecules per cu cm. A base-catalyzed second-order hydrolysis rate constant of 0.11 L/mole-sec(SRC) was estimated using a structure estimation method; this corresponds to half-lives of 2 years and 70 days at pH values of 7 and 8, respectively. The predicted near-surface half-life for the photosensitized oxidation of methyl oleate in near suface waters in the Southern US is 1100 hrs. Methyl oleate is not expected to directly photolyze due to the lack of absorption in the environmental UV spectrum.The Henry's Law constant for methyl oleate is estimated as 0.014 atm-cu m/mole(SRC) using a fragment constant estimation method. This Henry's Law constant indicates that methyl oleate is expected to volatilize rapidly from water surfaces. Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec) is estimated as approximately 5 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec) is estimated as approximately 7 days(SRC). The volatilization half-life from a model pond 2 m deep is estimated to be about 61 hours ignoring adsorption; when considering maximum adsorption the volatilization half-life increases to 18 months. Methyl oleate's Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). Methyl oleate is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 6.3X10-6 mm Hg.Methyl oleate produces small amounts of allylic keto-oleates (with CO on carbons 8-, 9-, 10- and 11), epoxy-stearate or epoxy-oleates (8,9-, 9,10- and 10,11-epoxy), dihydroxy-oleates (8,9-, 9,10-, and 10,11-diOH) and dihydroxystearates (between carbon-9 and carbon-11). The allylic keto-oleates may be derived by dehydration of the corresponding hydroperoxides. 9,10-Epoxystearate may be produced by the reaction of oleate and the hydroperoxides. The other epoxy products can be formed by cyclization of an alkoxy radical formed from the corresponding hydroperoxides of oleate. Accordingly, the 11-hydroperoxide forms the 10,11-epoxy ester, the 8-hydroperoxide forms the 8,9-epoxy ester, and the 9- and 10-hydroperoxides form the 9,10-epoxy ester. The 1,2- and 1,4-dihydroxy esters may be formed from a similar alkoxyl radical that undergoes hydroxyl and hydrogen radical substitution via an allylic hydroxy ester radical.Acrylated methyl oleate (AMO) was synthesized using methods reported by Bunker and Wool [4]. The monomer synthesis requires two steps. First, the unsaturated bond in oleic methyl ester (OME) must be epoxidized by a peroxy acid. The epoxidized fatty acid methyl ester is then acrylated using acrylic acid. The acrylate groups are able to participate in free-radical polymerization. A schematic of the monomer synthesis is shown in Fig. 12.2. The OME can also be derived as a by-product from biodiesel, assuming that we have an efficient fatty acid separation process. The separation process was explored by Bunker and Wool and potentially can be done economically at large scale. This would circumvent the need for the development of specialty high-oleic oils and provide additional utilization of biodiesel plants currently being constructed in Delaware and elsewhere. From a green engineering perspective, the biodiesel is perhaps more valuable as a chemical feedstock rather than a combustible fuel feedstock and can attain this value when the current generation of internal combustion engines is replaced in the future by their fuel-cell equivalents.They also demonstrated that jojoba oil undergoes facile ene addition reactions with these two enophiles. Recently, Biswas et al.119 studied the ene reaction of soybean oil with diethyl azodicarboxylate and observed a self-curing and thickening behavior at room temperature, which are believed to be due to cross-linking ene reactions. The ene adducts between soybean oil and diethyl azodicarboxylate were subjected to hydrolysis and alcoholysis reactions by chemical and enzymatic methods.120 Chemical hydrolysis yielded hydrazino-fatty acids, while enzymatic alcoholysis with methanol, glycerol, and poly(ethylene glycol) yielded the corresponding transesterified products.In sheet metal-forming processes, lubricants that can provide corrosion protection and scratch resistance are necessary to prevent material transfer from the sheet metal to the tool surface and to control friction. While a silane film can give good corrosion protection properties, it is often too thin to prevent such galling. With the desire to use environment-friendly pretreatments in the surface engineering of metal substrates,121 the proper choice of silane pretreatment of a metal surface, along with a vegetable oil coupled to the surface, can provide the desired lubrication properties. The coupling between a vegetable oil and a mercaptosilane was achieved through a photoinduced thiol–ene reaction using UV radiation.122 The thiol–ene coupling reaction of 2-ethyl-(hydroxymethyl)-1,3-propanediol trimercapto acetate and 2-ethyl-(hydroxymethyl)-1,3-propanediol trimercapto propionate with methyl oleate and methyl linoleate was evaluated by Samuelsson et al.123 Both thiols were more prone to add to the monounsaturated methyl oleate than to methyl linoleate, which contains two unconjugated double bonds. Real-time infrared (IR) measurements also showed that the cis-unsaturation in methyl oleate isomerized much more quickly than in methyl linoleate, and this also had an impact on the overall addition rate of the thiols because a trans-unsaturation was more reactive than a cis-unsaturation.Some of the more recent developments utilizing the ene reaction of vegetable oils are in the area of coatings and thermoset resins. Vinyl alkoxysilanes and vinyl acetoxysilanes have been grafted onto unsaturated vegetable oils to synthesize moisture-curable coatings.124 Similarly, butanethiol has been used in UV-initiated thiol–ene reactions with canola and corn oils.125 High butanethiol-to-vegetable-oil ratios and low reaction temperatures were used to effect high conversion of the double bonds and obtain high yields. Rubbery, thermoset polymers have been synthesized using the ene reaction between soybean oil and p-nitrosobenzene.126 High-performance thermosetting resins have also been prepared from DCO and 1,1′-(methylenedi-4,1-phenylene)bismaleimide.127 Similarly, grafted autoxidizable polyester resins for high-solid alkyd coating compositions have been reported, which utilize an ene adduct between natural oils and a diacid or its anhydride.No reproductive or developmental toxicity information was found for biodiesel. Methyl oleate was tested in a limited study design in which female rats, exposed to 100 mg kg−1 day−1 for 12 weeks, were bred to unexposed males. There were no effects to reproductive parameters.Several oils used as feedstocks for biodiesel have been evaluated for reproductive or developmental toxicity potential in limited testing. For tallow, a three-generation study in pigs and a one-generation study in rats failed to identify adverse effects to reproduction or offspring. In the rat study, the fatty acid profiles in fat tissues of newborn rats contained higher 14:0 and 18:0 content, reflecting the tallow composition in the diet. A screening study for developmental toxicity in rats administered palm oil at doses up to 3 ml kg−1 (ca. 2760 mg kg−1 day−1) resulted in prenatal mortality (resorptions), defects, and growth retardation, but the authors hypothesized that the effects may have been due to high vitamin A in the palm oil sample. Testing with palm oil for effects on sexual maturation and endocrine function, with the control group given corn oil and a second group controlling for fat content, found that vaginal opening occurred earlier in female rats given a high-fat diet. To the authors, this suggested that body weight or body fat was a factor in acceleration of vaginal patency, as there were no differences in average body weights at first estrus, no irregularities in estrous cyclicity, and no measured differences during the estrous cycles for estradiol, prolactin, or luteinizing hormone.Biodiesel exhaust (B100 soy-derived, 0.5 mg particulates per cubic meter per day) did not cause developmental toxicity in rats.
METHYL OLEATE ( OLEATE DE METHYLE )
Methyl 4-hydroxybenzoate; Methyl Chemosept; Methyl Parasept; 4-Hydroxybenzoic acid methyl ester; Nipagin M; Tegosept M; Aseptoform; Nipagin; 4-Hydroxy methyl benzoate CAS NO. : 99-76-3
Methyl Palmitate / Oleate
SYNONYMS (C16-18) And C18 Unsaturated Alkylcarboxylic Acid, Methyl Ester;n-Hexadecanoic acid methyl ester, Methyl hexadecanoate, Palmitic acid methyl ester;Z)-9-octadecenoic acid methyl ester;Methyl 9-octadecenoate; Methyl cis-9-Octadecenoate; Oleic acid Methyl ester Cas No:112-62-9
METHYL PARABEN
Chemical name: Methyl 4-Hydroxybenzoate Chemical structure INCI designation Methylparaben Product properties Appearance (20°C): White, crystalline powder. Chemical and physical data Melting point: 125 - 128 oC Assayacc. BP/PH.Eur: 98.0 - 102.0 % EC / List no.: 202-785-7 CAS no.: 99-76-3 Uses METHYL PARABEN is a broad spectrum antimicrobial agent designed for preservation of a wide range of cosmetics, toiletries and topical pharmaceuticals. METHYL PARABEN is suitable to preserve both rinse- off and leave- on formulations. Applications Typical use concentrations of METHYL PARABEN is 0.1 – 0.3 %. Combinations of p- Hydroxybenzoic acid esters, e.g.with Nipasol M, Nipagin A or Nipabutyl exhibit increased activity compared with individual esters. Incorporation METHYL PARABEN is freely soluble in most oils, waxes, fatty alcohols, but have relatively low solubility in water. The low aqueous solubility does not affect the microbiological efficacy of the esters. Most formulations requiring preservation contain a significant amount of water. This may mean that METHYL PARABEN cannot readily be added directly to the formulation. Other methods of incorporation are quite straightforward however, and are listed below. Dissolving in water The solubility of METHYL PARABEN increases greatly as the temperature of the water rises. Therefore a concentrate may be made up by heating an appropriate quantity of water to 60- 100 °C prior to addition of METHYL PARABEN. This concentrate may then be added to the formulation, provided that the ester concentration does not exceed its solubility in the formulation at normal ambient temperatures. Dissolving in organic solvents METHYL PARABEN is readily soluble in polar organic solvents. Where such a solvent is already part of a formulation an METHYL PARABEN concentrate may be made up prior to addition. If a suitable solvent is not already part of the formulation,a highly concentrated solution may be made up e.g. 32 % in Ethanol, which would give insignificant residual levels of ethanol in the end product. Solubilisation in oils, emulsifiers etc. METHYL PARABEN is readily soluble in lipophilic ingredients and may be introduced to a formulation by adding to the oil phase with some warming before any emulsification stage. In multiphase systems, such as emulsions, it is often advisable to use a combination of aqueous dissolution with either of the other methods to ensure adequate preservation. The ester may be incorporated in the water to its maximum solubility and any further quantities may be dissolved in the oil phase, or solvent, as appropriate. pH stability METHYL PARABEN remains fully stable over a wide pH range from 4- 8. In general the lower the pH of the formulation, the more active is METHYL PARABEN. That can result in a lower use concentration when the pH of the formulation is more acidic. Temperature stability METHYL PARABEN is stable up to 80 °C. METHYL PARABEN is the best water soluble short-chain Paraben. Benefits Broad spectrum of activity against bacteria and fungi Low order of toxicity Effectiveness at low concentrations Stability over a broad pH-range Water-soluble Biodegradability at environmental concentrations Global acceptance in personal care applications Solubility The solubility of METHYL PARABEN in different solvents is illustrated in the following table. Solvent % (w/w) Water 10 °C 0.13 Water 25 °C 0.25 Water 80 °C 3.1 Water 100 °C 6.2 Acetone 39 Methanol 37 Ethanol 32 Propylene Glycol 26 Glycerol 3.3 Vegetable oils (arachis) 2.4 Liquid paraffin 0.02 Microbial Activity METHYL PARABEN exhibits microbiostatic activity against a wide range of bacteria, yeast and mould. This is illustrated by the following table which shows the minimum inhibitory concentration (MIC) of METHYL PARABEN against examples of different groups of microorganisms. Microorganisms MIC level (%) Gram Negative Bacteria Pseudomonas aeruginosa 0.20 Escherichia coli 0.10 Klebsiella aerogenes 0.075 Klebsiella pneumoniae 0.10 Serratia marcescens 0.075 Proteus vulgaris 0.10 Salmonella enteritidis 0.15 Salmonella typhi 0.15 Microorganisms MIC level (%) Gram Positive Bacteria Stpahylococcus aureus 0.15 Streptococcus haemolyticus 0.10 Bacillus cereus 0.075 Bacillus subtilis 0.10 Lactobacillus buchneri 0.10 Yeasts Candida albicans 0.10 Saccharomyces cerevisiae 0.10 Molds Aspergillus niger 0.10 Penicillium digitatum 0.05 Rhizopus nigricans 0.05 Storage instructions The product must be stored in tighly closed container in a cool, well- ventilated, dry place. Further information on handling, storage and dispatch is given in the EC safety data sheet Methylparaben, also methyl paraben, one of the parabens, is a preservative with the chemical formula CH3(C6H4(OH)COO). Methylparaben is the methyl ester of p-hydroxybenzoic acid. Natural occurrences Methylparaben serves as a pheromone for a variety of insects and is a component of queen mandibular pheromone. It is a pheromone in wolves produced during estrus associated with the behavior of alpha male wolves preventing other males from mounting females in heat. Uses Methylparaben is an anti-fungal agent often used in a variety of cosmetics and personal-care products. It is also used as a food preservative and has the E number E218. Methylparaben is commonly used as a fungicide in Drosophila food media at 0.1%.[5] To Drosophila, methylparaben is toxic at higher concentrations, has an estrogenic effect (mimicking estrogen in rats and having anti-androgenic activity), and slows the growth rate in the larval and pupal stages at 0.2%.[6] Safety There is controversy about whether methylparaben or propylparabens are harmful at concentrations typically used in body care or cosmetics. Methylparaben and propylparaben are considered generally recognized as safe (GRAS) by the USFDA for food and cosmetic antibacterial preservation. Methylparaben is readily metabolized by common soil bacteria, making it completely biodegradable. Methylparaben is readily absorbed from the gastrointestinal tract or through the skin. It is hydrolyzed to p-hydroxybenzoic acid and rapidly excreted in urine without accumulating in the body. Acute toxicity studies have shown that methylparaben is practically non-toxic by both oral and parenteral administration in animals. In a population with normal skin, methylparaben is practically non-irritating and non-sensitizing; however, allergic reactions to ingested parabens have been reported. A 2008 study found no competitive binding for human estrogen and androgen receptors for methylparaben, but varying levels of competitive binding were seen with butyl- and isobutyl-paraben. Preferred IUPAC name Methyl 4-hydroxybenzoate Other names Methyl paraben; Methyl p-hydroxybenzoate; Methyl parahydroxybenzoate; METHYL PARABEN; E number E218; Tegosept; Mycocten Identifiers CAS Number: 99-76-3 Methyl 4-hydroxybenzoate This information is based on our present state of knowledge and is intended to provide general notes on our products and their uses. It should not therefore be construed as guaranteeing specific properties of the products described on their suitability for a particular application. Any existing industrial property rights must be observed. The quality of our products is guaranteed under our General Conditions of Sale.
Methyl paraben
Methyl 4-hydroxybenzoate, sodium salt; Sodium 4-(methoxycarbonyl)phenolate; Natrium-4-(methoxycarbonyl)phenolat; 4-(metoxicarbonil)fenolato de sodio; 4-(méthoxycarbonyl)phénolate de sodium; Methyl paraben sodium salt; Sodium methyl 4-hydroxybenzoate; methyl-4-oxide-benzoate, sodium salt; Methyl p-hydroxybenzoate, sodium salt CAS NO: 5026-62-0
Methyl paraben sodium
4-hydroxybenzoate de méthyle, méthylparabène parahydroxybenzoate de méthyle, No CAS :99-76-3, Le 4-hydroxybenzoate de méthyle ou méthylparabène (E2184) est un conservateur de la famille des parabènes. Il est utilisé dans les cosmétiques, les médicaments et les aliments, pour ses propriétés antibactériennes et antifongiques.Benzoic acid, p-hydroxy-, methyl ester;Benzoic acid, p-hydroxy-, methyl ester (6CI,8CI), 4-(Carbomethoxy)phenol, 4-(Methoxycarbonyl)phenol, 4-Hydroxybenzoic acid methyl ester, 4-Hydroxymethyl benzoate, Methyl 4-(3'-butenyloxy)benzoate; methyl parabel [INCI]; METHYL PARABEN; methyl-4-hydroxybenzoate
METHYL PARABEN( Paraoxybenzoate de méthyle )
Synonyms: AKOS BBS-00004393;4-(methoxycarbonyl)phenol;4-HYDROXYBENZOIC ACID METHYL ESTER;4-HYDROXYBENZOIC ACID METYL ESTER;4-(carbomethoxy)phenol;METHYLIS PARAHYDROXYBENZOAS;METHYLPARABEN;Methyl parasept CAS: 99-76-3
METHYL P-HYDROXYBENZOATE (METHYL PARABEN)
NMP; n-methyl-2-pyrrolidone; N-Methyl pyrrolidone; N-Methylpyrrolidone; N° CAS : 872-50-4, Nom INCI : METHYL PYRROLIDONE. Nom chimique : N-methyl-2-pyrrolidone. N° EINECS/ELINCS : 212-828-1. Solvant : Dissout d'autres substances, 1-Méthyl-2-pyrrolidone, 1-Methyl-2-pyrrolidinone, 1-methyl-5-pyrrolidinone, 1-METHYLAZACYCLOPENTAN-2-ONE, 1-METHYLPYRROLIDINONE,1-METHYLPYRROLIDONE, 2-Pyrrolidinone, 1-methyl-, M-PYROL, N-METHYL-2-PYRROLIDINONE, n-methyl-2-pyrrolidone, N-METHYL-ALPHA-PYRROLIDINONE, N-METHYL-ALPHA-PYRROLIDONE,N-METHYL-GAMMA-BUTYROLACTAM, N-METHYLPYRROLIDINONE, N-Methylpyrrolidone, NMP, METHYL PYRROLIDONE, Noms français :1-Methyl-2-pyrrolidinone; 1-Methyl-2-pyrrolidone; 1-METHYL-5-PYRROLIDINONE; 1-METHYLAZACYCLOPENTAN-2-ONE; 1-METHYLPYRROLIDINONE; 1-METHYLPYRROLIDONE-2; 2-PYRROLIDINONE, 1-METHYL-; M-Pyrol; METHYLPYRROLIDINONE ;Méthyl-1 pyrrolidinone-2; N-METHYL PYROLIDINONE; N-METHYL-2-PYRROLIDINONE ;N-METHYL-ALPHA-PYRROLIDINONE; N-METHYL-ALPHA-PYRROLIDONE ;N-METHYLPYROLIDINONE; N-METHYLPYROLIDONE ;N-METHYLPYRROLIDINONE; N-Méthyl 2-pyrrolidone; N-Méthyl pyrrolidone; N-Méthyl pyrrolidone-2. Noms anglais :N-Methyl pyrrolidone; N-Methylpyrrolidone Utilisation: La N-méthyl 2-pyrrolidone est un solvant industriel utilisé dans différents secteurs d'activité. Les principales utilisations de la N-méthyl 2-pyrrolidone qu'on peut rencontrer dans les établissements québécois sont : dans les produits de nettoyage industriels que ce soit comme composant principal de décapants à peinture, de dégraisseurs ou de nettoyeurs pour surface de métal (enlèvement des huiles, graisses, suies, dépôts de carbone et autres résidus goudronneux dans les moteurs à combustion) en plus faible concentration dans les nettoyeurs à graffitis et les produits de nettoyage domestiques dans la formulation de peintures et revêtements, dont certaines peintures et finis à base d'eau, des revêtements pour séchage au four et d'autres à base de mélanges de solvants en imprimerie, dans la formulation des encres, comme dispersant de pigments, ou en mélange avec d'autres solvants pour nettoyer les écrans ou autres surfaces en électronique, comme solvant de nettoyage pour les plaques de silicium (semi-conducteur), décapant de résines photosensibles (circuit imprimé), ou solvant de nettoyage de résidus d'enrobage ou autres résines dans l'industrie du plastique, comme solvant pour de nombreux polymères et copolymères ou comme milieu de réaction pour la production de polymères tels que les polyéthersulfones, les polyimides ou les aramides en agrochimie, comme solvant dans la formulation de pesticides dans l'industrie pharmaceutique, comme intermédiaire de synthèse, dans les formulations de médicaments à application topique pour augmenter la pénétration ou comme solvant de produits cosmétiques.N-Methylpyrrolidione; N-Methylpyrrolidone; 106420 [Beilstein]; 1-Methyl-2-pyrrolidinon [German] [ACD/IUPAC Name]; 1-Methyl-2-pyrrolidinone [ACD/IUPAC Name] 1-Méthyl-2-pyrrolidinone [French] [ACD/IUPAC Name]; 1-Methyl-2-pyrrolidone; 1-Methylpyrrolidin-2-on; 1-methylpyrrolidin-2-one; 212-828-1 [EINECS]; 2-Pyrrolidinone, 1-methyl- [ACD/Index Name]; 2-Pyrrolidone, 1-methyl; 872-50-4 [RN]; Methyl pyrrolidone; METHYLPYRROLIDINONE; Methylpyrrolidone [Wiki]; Methylpyrrolidone, N-MFCD00003193 [MDL number] ;N-methyl pyrrolidinone; N-methyl-2-pyrrolidinone; N-Methyl-2-pyrrolidone;N-Methyl-a-pyrrolidinone; N-Methyl-g-butyrolactone; N-methylpyrrolidinone; N-Methyl-α-pyrrolidinone; N-methyl-α-pyrrolidone; N-Methyl-α-pyrrolidone; NMP [Formula]; Pyrrolidinone, methyl-; 185964-60-7 [RN];1-METHYL-2-PYRROLIDI; 1-Methyl-2-pyrrolidon; 1-Methyl-5-pyrrolidinone; 1-methylazacyclopentan-2-one; 1-Methylazacyclopentane-2-one; 1-Methyl-pyrrolidin-2-one; 1-Methylpyrrolidinone; 1-METHYLPYRROLIDINONE-5,5-D2; 1-Methylpyrrolidone; 204-438-5 [EINECS]; 2-Pyrrolidinone, methyl-; 2-Pyrrolidone, 1-methyl-; Agsolex 1; MB3; Methyl-2-pyrrolidinone;METHYLPYRROLIDIN-1-YLNE; M-Pyrol; N-methyl pyrrolidone; N-Methyl-2-ketopyrrolidine; N-methyl-2-pyrolidinone;N-Methyl-2-pyrrolidinone ACS reagent; N-Methylbutyrolactam; N-Methyl-d3-2-pyrrolidinone-d6; N-METHYLPYROLIDONE; N-Methylpyrrolid-2-one; N-methylpyrrolidin-2-one; N-Methylpyrrolidione (en); N-methyl-pyrrolidone; N-methyl-α-pyrrolidinone; N-methyl-γ-butyrolactam; N-Methyl-γ-butyrolactam; N-甲基吡咯烷酮 [Chinese]; pyrrolidin-2-one, 1-methyl-; T5NVTJ A [WLN]; 1-Methyl-2-pyrrolidinone; 1-methyl-2-pyrrolidone; EC Inventory, , , ; 1-Methyl-2-pyrrolidone (NMP); Candidate List; 1-Methyl-5-pyrrolidinone; 1-Methylazacyclopentan-2-one; 1-Methylpyrrolidinone; 1-Methylpyrrolidone; 2-Pyrrolidinone, 1-methyl-; AgsolEx 1; Methylpyrrolidone; Microposit 2001;N-Methyl-2-pyrrolidinone; N-Methyl-2-pyrrolidone; N-Methyl-gamma-butyrolactam; N-Methylpyrrolidinone; N-methylpyrrolidone; NMP; Pharmasolve; Pyrol M; SL 1332; Translated names: 1-methyl-2-pyrrolidon (da); 1-methylpyrrolidin-2-on (cs); 1-metil-2-pirolidon (hr);1-metil-2-pirolidonas (lt); 1-metil-2-pirolidons (lv); 1-metil-2-pirolidonă (ro); 1-metil-2-pirrolidon (hu); 1-metil-2-pirrolidona (es); 1-metil-2-pirrolidone (it); 1-metyl-2-pyrrolidon (no);1-metylo-2-pirolidon (pl); 1-metylpyrolidín-2-ón (sk); 1-metyyli-2-pyrrolidoni (fi); 1-metüül-2-pürrolidoon (et); 1-méthyl-2-pyrrolidone (fr); 1-μεθυλο-πυρρολιδόνη-2 (el); 1-метил-2-пиролидон (bg); N-metil-2-pirolidon (hr); N-methyl-2-pyrrolidon (cs); N-metil-2-pirolidon (sl); N-metil-2-pirolidonas (lt); N-metil-2-pirolidons (lv); N-metil-2-pirolidonă (ro); N-metil-2-pirrolidon (hu); N-metil-2-pirrolidona (es); N-metil-2-pirrolidone (it); N-metyl-2-pyrolidón (sk); N-metyl-2-pyrrolidon (no); N-metylo-2-pirolidon (pl); N-metyyli-2-pyrrolidoni (fi); N-metüül-2-pürrolidoon (et); N-méthyl-2-pyrrolidone (fr); N-μεθυλο-πυρρολιδόνη-2· (el); N-метил-2-пиролидон (bg); : 1-mehyl-2-pyrrolodone; 1-Methyl 2-pyrrolidone; 1-methylpyrrolidin-1-one; 1-methylpyrrolidin-2-one; 1-methylpyrrolidin-2-one,N-METHYLPYRROLIDONE, 1-Methyl-2-pyrrolidinone, N-METHYL-2-PYRROLIDONE; 1-O-butyl 2-O-(phenylmethyl) benzene-1,2-dicarboxylate; 2-Pyrrolidone, 1-methyl; Methyl pyrrolidone; METHYL-N 2-PYRROLIDONE; n methyl 2 pyrrolidone;N-Methyl pyrolidone; N-methyl-2-pyrolidone; N-methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone; NMP (n-methyl-2-pyrrolidone); Trade names;2-Pyrrolidinone, 1-methyl- (7CI, 8CI, 9CI); 2-Pyrrolidinone, 1-methyl-(7Cl, 8Cl, 9Cl); M-Pyrol; N-methyl pyrrolidone; N-Methyl-.alpha.-pyrrolidinone;N-Methyl-.alpha.-pyrrolidone;N-Methyl-.gamma.-butyrolactam; N-METHYLPYROLIDONE;N-Methylpyrrolidon; n-methylpyrrolidon in Lube Green preparation; POLYFLON PTFE SM-3900; Pyrol-M
METHYL PROXITOL GLYCOL ETHER
Methyl Proxitol Glycol Ether has a clear liquid form
Methyl Proxitol Glycol Ether is mainly used as Nitro fiber, alkyd resin and maleic anhydride modified phenolic resin excellent solvent
Methyl Proxitol Glycol Ether is used as jet fuel antifreeze and brake fluid additives;


CAS NUMBER: 107-98-2

EC NUMBER: 203-539-1

MOLECULAR FORMULA: H3CCHOHCH2OCH3

MOLECULAR WEIGHT: 90.12 g/mol

IUPAC NAME: 1-methoxypropan-2-ol


Methyl Proxitol Glycol Ether is mainly used as solvent, dispersant and diluent
Methyl Proxitol Glycol Ether is the methyl ether of propylene glycol (PM)
Methyl Proxitol Glycol Ether acetate is the acetate of the methyl ether of propylene glycol (PMA).

Methyl Proxitol Glycol Ether is used in coating products
Methyl Proxitol Glycol Ether is used in washing & cleaning products
Methyl Proxitol Glycol Ether is used in plant protection products
Methyl Proxitol Glycol Ether is used in adhesives and sealants
Methyl Proxitol Glycol Ether has an industrial use resulting in manufacture of another substance (use of intermediates).

Methyl Proxitol Glycol Ether is used agriculture, cosmetics, electronics, ink, textile and adhesive products.
Methyl Proxitol Glycol Ether (PGMEA, 1-methoxy-2-propanol acetate) is a P-type glycol ether used in inks, coatings, and cleaners.

Methyl Proxitol Glycol Ether is completely water-soluble and is also compatible with many greases, oils and waxes, which makes PM an excellent coupling agent.
Methyl Proxitol Glycol Ether is used in cleaning applications.

Methyl Proxitol Glycol Ether is used in a variety of applications including:
Methyl Proxitol Glycol Ether is used in coatings

Methyl Proxitol Glycol Ether is soluble in water
Methyl Proxitol Glycol Ether is highly flammable.
Methyl Proxitol Glycol Ether is a methoxy alcohol derivative
Methyl Proxitol Glycol Ether is chemical formula is C4H10O2.

In the semiconductor industry, Methyl Proxitol Glycol Ether is a commonly used solvent, primarily for the application of surface adherents such as Bis(trimethylsilyl)amine (HMDS) on silicon wafers.
Methyl Proxitol Glycol Ether is an organic solvent with a wide variety of industrial and commercial uses.

Methyl Proxitol Glycol Ether is also used as a cleaning agent in the LCD and electronics industry.
Methyl Proxitol Glycol Ether is used as a reagent in the synthesis of 2-amino-3-carboxy-4-phenylthiophenes, which acts as a protein kinase C inhibitors.
Methyl Proxitol Glycol Ether is also used as a reagent in the synthesis of metolachlor.
Methyl Proxitol Glycol Ether acts as a good biological indicator.
Further, Methyl Proxitol Glycol Ether is used as a solvent and an antifreeze agent.

Methyl Proxitol Glycol Ether is also used as fuel antifreeze, extractant
Methyl Proxitol Glycol Ether is used in reformulation to compensate for the absence of aromatics to control viscosity and their ability to "double" aqueous and organic phases.

Methyl Proxitol Glycol Ether can be used in automotive industry
Methyl Proxitol Glycol Ether also used in paints

Methyl Proxitol Glycol Ether is used in a variety of applications including:
-Coatings
■ Automotive
■ Industrial Maintenance
■ Architectural
■ Aerospace
■ Speciality Paints

-Cleaners & Inks
■ All-Purpose
■ Oven
■ Industrial
■ Household
■ Flexographic
■ Screen Printing

-Electronics
■ Copper Clad Laminating
■ Laminates
■ Photoresistors

-Other
■ Adhesives
■ Pharmaceuticals
■ Cosmetics
■ Industrial Processes
■ Oil Field Chemicals
■ Mining Chemicals
■ Agricultural Chemicals
■ Textile & Leather Dyes


Methyl Proxitol Glycol Ether also finds use as an industrial and commercial paint stripper.
Methyl Proxitol Glycol Ether is used as an antifreeze in diesel engines.

Methyl Proxitol Glycol Ether is used in manufacturing of cleaners
Methyl Proxitol Glycol Ether is completely water-soluble and is also compatible with many resins, greases, oils and waxes.


PHYSICAL PROPERTIES:

-Molecular Weight: 90.12 g/mol

-XLogP3-AA: -0.2

-Exact Mass: 90.068079557 g/mol

-Monoisotopic Mass: 90.068079557 g/mol

-Topological Polar Surface Area: 29.5Ų

-Physical Description: Clear, colorless liquid with a mild, ethereal odor

-Color: Colorless

-Form: Liquid

-Odor: Weak pleasant odor

-Taste: Bitter Taste

-Boiling Point: 120 °C

-Melting Point: -95 °C

-Flash Point: 97 °F

-Solubility in water: Miscible

-Density: 0.924

-Vapor Density: 3.11

-Vapor Pressure: 12.5 mmHg

-Autoignition Temperature: 270 °C

-Viscosity: 1.81 mPa-s

-Surface Tension: 27.7 dynes/cm

-Refractive Index: 1.4034


Methyl Proxitol Glycol Ether is used as a solvent, dispersant or diluent used in coating, ink, printing and dyeing, pesticide, cellulose, acrylate and other industries.
Methyl Proxitol Glycol Ether can also be used as a fuel antifreeze, a cleaning agent, an extractant, a non-ferrous metal ore dressing agent, etc.
Methyl Proxitol Glycol Ether can also be used as a raw material for organic synthesis.

Methyl Proxitol Glycol Ether is used as a reagent in the synthesis of metolachlor.
Methyl Proxitol Glycol Ether acts as a good biological indicator.
Methyl Proxitol Glycol Ether is a colorless
Methyl Proxitol Glycol Ether is flammable, and liquid organic compound


CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 1

-Hydrogen Bond Acceptor Count: 2

-Rotatable Bond Count: 2

-Heavy Atom Count: 6

-Formal Charge: 0

-Complexity: 28.7

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 1

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 1

-Compound Is Canonicalized: Yes

-Chemical Classes: Solvents -> Glycol Ethers


Methyl Proxitol Glycol Ether (PGME) is used as a solvent material in paint and coating processes, inks, cosmetics and cleaning agents used in industrial and domestic applications.
Methyl Proxitol Glycol Ether is used as a solvent and as an antifreeze agent.

Methyl Proxitol Glycol Ether is a colourless
Methyl Proxitol Glycol Ether is hygroscopic solvent with a volatility, viscosity and solvent power similar to those of ethylene oxide-based glycol ethers.

Methyl Proxitol Glycol Ether is used as an ink thinner:
Methyl Proxitol Glycol Ether provides good solubility for a wide range of resins including acrylic, epoxy, alkyd, polyester, nitrocellulose and polyurethane.

Methyl Proxitol Glycol Ether belongs to the family of glycol ethers.
Methyl Proxitol Glycol Ether is also known as propylene glycol monomethyl ether (PGME) and has the chemical formula C4H10O2.
Methyl Proxitol Glycol Ether is widely used as a solvent
Methyl Proxitol Glycol Ether has a high boiling point

Methyl Proxitol Glycol Ether is colorless transparent volatile liquid.
Methyl Proxitol Glycol Ether's relative density is 0.9234.

Methyl Proxitol Glycol Ether is used Water-based Coatings
Methyl Proxitol Glycol Ether is used Solvent-based Coatings
Methyl Proxitol Glycol Ether is used Household and Industrial cleaners, grease and paint removers, metal cleaners, and hard surface cleaners.

Methyl Proxitol Glycol Ether's boiling Point is 121 °C.
Methyl Proxitol Glycol Ether's Vapor pressure is 1070Pa.

Methyl Proxitol Glycol Ether has low volatility
Methyl Proxitol Glycol Ether has water solubility and this makes it ideal for various industrial processes.
Methyl Proxitol Glycol Ether is a common ingredient in paints, coatings, and printing inks
Methyl Proxitol Glycol Ether is also used in the production of hydraulic fluids, industrial cleaners, and cosmetics.

Methyl Proxitol Glycol Ether is the methyl ether of propylene glycol and has a slightly lower boiling point and higher evaporation rate than its Ethyl Proxitol counterpart.
Methyl Proxitol Glycol Ether is completely water soluble and also compatible with many resins, greases, oils and waxes.

Methyl Proxitol Glycol Ether is soluble in water
Methyl Proxitol Glycol Ether has a high boiling point and low vapor pressure
Methyl Proxitol Glycol Ether is a stable compound
Methyl Proxitol Glycol Ether does not react with most common chemicals.

Methyl Proxitol Glycol Ether can be used in cleansing, smudge removal and masking.
Methyl Proxitol Glycol Ether is also used in the agricultural, cosmetic, and printing industries as a retarder for printing on textiles and polymer products with alcohol-soluble inks.

Methyl Proxitol Glycol Ether is used Agro-chemicals
Methyl Proxitol Glycol Ether is used Printing Chemicals and Inks
Methyl Proxitol Glycol Ether is used as a solvent in paints, inks, nail polish removers, and cleaning agents.

Methyl Proxitol Glycol Ether is an organic solvent with a wide variety of industrial and commercial uses.
Methyl Proxitol Glycol Ether is a hydrophilic glycol ether with a fast evaporation rate and excellent coupling abilities including high water solubility and active solvency.

Methyl Proxitol Glycol Ether is a colorless liquid
Methyl Proxitol Glycol Ether has a sweet ether-like odor and bitter taste.
Methyl Proxitol Glycol Ether is soluble in water, ether, acetone, and benzene.
Methyl Proxitol Glycol Ether is primarily used in the manufacture of lacquers and paints

Methyl Proxitol Glycol Ether is used in finishing leather and in electronics and agriculture.
Methyl Proxitol Glycol Ether is used to make lacquers and paints, as a solvent for resins, celluloses, acrylics, dyes, and inks (gravure, flexographic and silk screening)
Methyl Proxitol Glycol Ether used as antifreeze
Methyl Proxitol Glycol Ether can be used in household cleaners and spot removers.

Methyl Proxitol Glycol Ether is used as an anti-freeze in industrial engines
Methyl Proxitol Glycol Ether is used as a tailing agent for inks used on very high-speed presses
Methyl Proxitol Glycol Ether can be used as a coupling agent for resins and dyes in waterbased inks
Methyl Proxitol Glycol Ether also used as a solvent for celluloses, acrylics, dyes, inks, and stains.

Methyl Proxitol Glycol Ether is used in the following products:
-coating products
-washing & cleaning products
-anti-freeze products
-cosmetics
-personal care products
-biocides (e.g. disinfectants, pest control products)

Methyl Proxitol Glycol Ether is a colourless, hygroscopic solvent with a volatility, viscosity and solvent power similar to those of ethylene oxide-based glycol ethers.
Methyl Proxitol Glycol Ether has a colorless liquid.
Methyl Proxitol Glycol Ether exhibits excellent bonding performance with a variety of resins including acrylics, styrene acrylics and polyvinyl acetates.

Methyl Proxitol Glycol Ether acts as a good biological indicator.
Methyl Proxitol Glycol Ether is mainly used as solvent, dispersant and diluent
Methyl Proxitol Glycol Ether is used as solvent of nitrocellulose, compounding agent of brake oil and detergent, etc.
Methyl Proxitol Glycol Ether widely used in coatings and cleaners.

Ether and alcohol groups give Methyl Proxitol Glycol Ether bifunctionality with excellent binding properties in aqueous-organic systems.
Methyl Proxitol Glycol Ether's flash point is near 89°F.

Methyl Proxitol Glycol Ether is less dense than water.
Methyl Proxitol Glycol Ether's vapors heavier than air.

Methyl Proxitol Glycol Ether has a pleasant smell and can be used in various cleaning agents.
Methyl Proxitol Glycol Ether is particularly suitable when used in cleaning formulations such as wax scrapers and floor cleaners.

Methyl Proxitol Glycol Ether is a solvent for ballpoint pens and pens
Methyl Proxitol Glycol Ether is used as oupling agents and solvents for household and industrial cleaners, derusting agents and hard surface cleaners
Methyl Proxitol Glycol Ether is a colorless, water-miscible liquid with a mild alcohol smell and medium volatility.

Methyl Proxitol Glycol Ether mixes well with water and other organic solvents, dissolves many organic substances well, methoxypropanol can act as a substitute for many glycols (E-series).
Methyl Proxitol Glycol Ether is used as a solvent for printing inks
Methyl Proxitol Glycol Ether provides good solubility for a wide range of resins, including acrylic, epoxy, alkyd, polyester, nitrocellulose and polyurethane.


SYNONYMS:

1-Methoxy-2-propanol
107-98-2
1-Methoxypropan-2-ol
Methoxyisopropanol
Methoxyisopropanol
Propylene glycol methyl ether
Propylene glycol monomethyl ether
Propyleneglycol monomethyl ether
α-Propylene glycol monomethyl ether
(R)-1-Methoxypropan-2-ol
(R)-tert-butyl 3-formylpiperidine-1-carboxylate
(S)-1-Methoxypropan-2-ol
1,2-propylene glycol 1-monomethyl ether
2-Methoxy-1-methylethanol
2-Propanol, methoxy-
PGME
2-Propanol, 1-methoxy-
Closol
Propylene glycol monomethyl ether
Dowtherm 209
1-Methoxy-2-hydroxypropane
Propasol solvent M
Dowanol 33B
PROPYLENE GLYCOL METHYL ETHER
2-Methoxy-1-methylethanol
Methyl proxitol
2-Propanol, methoxy-
Propylene glycol 1-methyl ether
NSC 2409
Dowanol-33B
HSDB 1016
1-methoxy-propan-2-ol
EINECS 203-539-1
UN3092
BRN 1731270
UNII-74Z7JO8V3U
.alpha.-Propylene glycol monomethyl ether
AI3-15573
74Z7JO8V3U
Propyleneglycol monomethyl ether
DTXSID8024284
NSC-2409
EC 203-539-1
DTXCID804284
CAS-107-98-2
propyleneglycol monomethylether
Glycol ether pm
Ucar solvent lm
Solvent PM
Gylcol Ether PM
Icinol PM
methoxy isopropanol
Methoxy-2-propanol
MFCD00004537
1-methoxypropanol-2
1-Metoxipropan-2-ol
1-Metoksy-2-propanol
PME (CHRIS Code)
3-methoxy-propan-2-ol
Propan-1-methoxy-2-ol
2-Propanol, 1-metoxi-
rac-1-methoxy-2-propanol
1- methoxypropan- 2- ol
1,2-PROPYLENE GLYCOL 1-MONOMETHYL ETHER
2-methoxy-1-methyl ethanol
Propan-2-ol, 1-methoxy-
propylene glycol monomethylether
1-Methoxy-2-propanol, 98%
1-Methoxy-2-propanol (PGME)
Methoxypropanol, .alpha. isomer
(+/-)-1-methoxy-2-propanol
1 - methoxypropan - 2 - ol
CHEMBL3186306
METHOXYISOPROPANOL
NSC2409
WLN: QY1 & 1O1
propylene glycol mono methyl ether
(+/-)2-methoxy-1-methylethanol
Propylene Glycol 1-Monomethyl Ether
Tox21_201803
Tox21_303269
LS-444
NA3092
1-Methoxy-2-propanol
AKOS009158246
SB44649
SB44662
NCGC00249123-01
NCGC00256978-01
NCGC00259352-01
Propylene glycol monomethyl ether (PGME)
1-METHOXY-2-HYDROXYPROPANE
1-Methoxy-2-propanol
Propylene Glycol Methyl Ether Reagent Grade
FT-0608005
FT-0647598
FT-0654880
ALPHA-PROPYLENE GLYCOL MONOMETHYL ETHER
ARCOSOLV PM
FT-0655258
M0126
EN300-73396
E72455
PROPYLENE GLYCOL MONOMETHYL ETHER, ALPHA
1-Methoxy-2-propanol
Q1884806
1-Methoxy-2-propanol
Z825742124
InChI=1/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H
1-Methoxy-2-propanol
Z825742124
1-Methoxy-2-propanol
1-Methoxy-2-propanol (Propylene Glycol Methyl Ether)
1-methoxy-2-propanol monopropylene glycol methyl ether
1-Methoxy-2-propanol;
1-Methoxy-2-propanol; 2-Propanol, 1-methoxy-; Closol ...
1-methoxy-2-propanol; monopropylene glycol methyl ether
1-Methoxy-propan-2-ol
propylene glycol methyl ether
Propylene glycol methyl ether
Propylene glycol methyl ether [PGME] (CAS 107-98-2)
Propylene glycol monomethyl ether
Propylene glycol monomethyl ether
propylene glycol monomethylether
Propyleneglycol monomethyl ether
propyleneglycol monomethylether
triphenyl phosphite
METHOXY ETHER OF PROPYLENE GLYCOL
2-METHOXY-1-METHYLETHANOL
1-METHOXY-2-HYDROXYPROPANE
(+/-)-1-METHOXY-2-PROPANOL
1-METHOXY-2-PROPANOL
3-METHOXY-2-PROPANOL
METHOXYISOPROPANOL
METHOXYISOPROPANOL
1-Methoxy-2-propanol
1-Methoxy-2-hydroxypropane
1-Methoxy-2-propanol
1-Méthoxy-2-propanol
1-methoxypropan-2-ol
203-539-1
2-Propanol, 1-methoxy-
METHYL PROXITOL GLYCOL ETHER ACETATE
Methyl PROXITOL Glycol Ether Acetate is a colourless, neutral propylene oxide-based glycol ether acetate with a mild odour and a volatility, viscosity and solvent power similar to those of ethylene glycol-based glycol ether acetates, e.g. methyl and ethyl OXITOL acetates.
Methyl PROXITOL Glycol Ether Acetate is a P-type glycol ether used in inks, coatings, and cleaners.
Methyl PROXITOL Glycol Ether Acetate is sold by Dow Chemical under the name Dowanol PMA, by Shell Chemical under the name methyl proxitol acetate, and by Eastman under the name PM Acetate.

CAS: 108-65-6
MF: C6H12O3
MW: 132.16
EINECS: 203-603-9

In the semiconductor industry, Methyl PROXITOL Glycol Ether Acetate is a commonly used solvent, primarily for the application of surface adherents such as Bis(trimethylsilyl)amine (HMDS) on silicon wafers.
Methyl PROXITOL Glycol Ether Acetate is often the most abundant airborne, molecular contamination (AMC) in semiconductor cleanrooms, due to its evaporation into ambient air.
Methyl PROXITOL Glycol Ether Acetate, also known as propylene glycol monomethyl ether acetate, with molecular formula of C6H12O3, is a colorless hygroscopic liquid with special smell.
Methyl PROXITOL Glycol Ether Acetate is a non pollution solvent with multi-functional groups.

Methyl PROXITOL Glycol Ether Acetate is mainly used as the solvent of ink, paint, ink, textile dye and textile oil agent, and also as the cleaning agent in the production of LCD.
Flammable, may form explosive vapor / air mixture above 42 ° C.
Propylene glycol methyl ether acetate (PGMEA) is an advanced solvent.
Methyl PROXITOL Glycol Ether Acetate's molecule has both ether bond and carbonyl.
Carbonyl forms the structure of ester and contains alkyl at the same time.
In the same molecule, there are both non-polar and polar parts.

The functional groups of these two parts not only restrict and repel each other, but also play their inherent roles.
Therefore, Methyl PROXITOL Glycol Ether Acetate has a certain solubility for non-polar substances and polar substances.
Methyl PROXITOL Glycol Ether Acetate is a material contains polar groups and non polar group , has good ability of dissolving and coupling, commonly used in solvent based coatings and screen printing ink.
Using dipropylene glycol methyl ether and acetic acid as raw material, under the catalysis of solid acid, via esterification reaction to generated crude product and its high purity Methyl PROXITOL Glycol Ether Acetate after distillation.
Methyl PROXITOL Glycol Ether Acetate is a photoresist solvent.

Methyl PROXITOL Glycol Ether Acetate's degradation by microorganisms in different soil types has been investigated.
An oral reference dose (RfD) value of Methyl PROXITOL Glycol Ether Acetate has been obtained from inhalation studies.
The solubility of (5-alkylsulfonyloxyimino-5H-thiophen-2-ylidene)-2-methylphenyl-acetonitriles in Methyl PROXITOL Glycol Ether Acetate has been analyzed.
Methyl PROXITOL Glycol Ether Acetate is a low-toxic high-grade industrial solvent with excellent performance.
Methyl PROXITOL Glycol Ether Acetate has strong dissolving ability for polar and non-polar substances.
Methyl PROXITOL Glycol Ether Acetate is suitable for high-grade coatings and inks, various polymers solvents, including urethane, vinyl, Polyester, cellulose acetate, alkyd resin, acrylic resin, epoxy resin and nitrocellulose, etc.
Methyl PROXITOL Glycol Ether Acetate can also be used as a solvent for paints, inks, textile dyes, and textile oils.

Methyl PROXITOL Glycol Ether Acetate Chemical Properties
Melting point: -87 °C
Boiling point: 145-146 °C(lit.)
Density: 0.970 g/mL at 25 °C(lit.)
Vapor pressure: 3.7 mm Hg ( 20 °C)
Refractive index: n20/D 1.402
Fp: 110 °F
Storage temp.: Store below +30°C.
Solubility water: soluble198g/L at 20°C
Form: Liquid
Color: Clear colorless
PH:4 (200g/l, H2O, 20℃)
Odor: mild fruity odor
Explosive limit: 1.5%(V)
Water Solubility: 19.8 g/L (25 ºC)
BRN: 1751656
Stability: Stable. Flammable. Incompatible with strong oxidizing agents, acids, bases.
InChIKey: LLHKCFNBLRBOGN-UHFFFAOYSA-N
LogP: 1.2 at 20℃
CAS DataBase Reference: 108-65-6(CAS DataBase Reference)
NIST Chemistry Reference: Methyl PROXITOL Glycol Ether Acetate (108-65-6)
EPA Substance Registry System: Methyl PROXITOL Glycol Ether Acetate (108-65-6)

Methyl PROXITOL Glycol Ether Acetate is a clear, slightly hygroscopic liquid with a mild odour.
Methyl PROXITOL Glycol Ether Acetate is freely miscible with most common organic solvents, but has only limited miscibility with water.
By virtue of its ether and ester groups, Methoxypropyl Acetate enters into reactions that are characteristic of ethers and esters and display their solvent power.
For instance, Methyl PROXITOL Glycol Ether Acetate dissolves numerous natural and synthetic resins, waxes, fats and oils.
Since Methyl PROXITOL Glycol Ether Acetate may react with the oxygen in the air to form peroxides, BASF supplies it inhibited with 2.6-di-tert-butyl-para-cresol (butylated hydroxytoluene – BHT).

Uses
Methyl PROXITOL Glycol Ether Acetate is used as a solvent for paints, inks, lacquers, varnishes, cleaners and coatings.
Methyl PROXITOL Glycol Ether Acetate is also used as a solvent for degreasing circuit boards and in food contact applications.
Further, Methyl PROXITOL Glycol Ether Acetate is used in photoresist formulations in the semiconductor industry.
Methyl PROXITOL Glycol Ether Acetate is a high-grade industrial solvent with low toxicity and excellent performance.

Methyl PROXITOL Glycol Ether Acetate has strong solubility for polar and non-polar substances.
Methyl PROXITOL Glycol Ether Acetate is suitable for solvents of various polymers of high-grade coatings and inks, including aminomethyl ester, vinyl, polyester, cellulose acetate, alkyd resin, acrylic resin, epoxy resin and nitrocellulose.
Methyl PROXITOL Glycol Ether Acetate is the best solvent in coatings and inks.
Methyl PROXITOL Glycol Ether Acetate is suitable for unsaturated polyester, polyurethane resin, acrylic resin, epoxy resin, etc.

Synonyms
1-Methoxy-2-propyl acetate
108-65-6
1-methoxypropan-2-yl acetate
Propylene glycol methyl ether acetate
Propylene glycol monomethyl ether acetate
2-Acetoxy-1-methoxypropane
PGMEA
1-Methoxy-2-acetoxypropane
2-Methoxy-1-methylethyl acetate
2-Propanol, 1-methoxy-, acetate
METHOXYISOPROPYL ACETATE
1-METHOXY-2-PROPANOL ACETATE
Propyleneglycol monomethyl ether acetate
NSC 2207
Acetic acid, 2-methoxy-1-methylethyl ester
2-Propanol, 1-methoxy-, 2-acetate
EINECS 203-603-9
Dowanol (R) PMA glycol ether acetate
UNII-PA7O2U6S2Q
PROPYLENEGLYCOLMETHYLETHERACETATE
BRN 1751656
PA7O2U6S2Q
2-(1-Methoxy)propyl acetate
Propylene glycol 1-methyl ether 2-acetate
AI3-18548
DTXSID1026796
Propylene Glycol 1-Monomethyl Ether 2-Acetate
NSC-2207
propylene glycol monomethylether acetate
EC 203-603-9
Arcosolv PMA
Dowanol PMA
MFCD00038500
2-Propanol, acetate
Ektasolve PM Acetate
1,2-Propanediol monomethyl ether acetate
PGN (CHRIS Code)
SU 8 DEVELOPER
1-Metoksy-2-propylacetat
1-Methoxypropyl-2-acetate
1-methoxy-2-acetoxy propane
SCHEMBL15667
2-methoxy-1-methylethylacetat
2-methoxy-1-methylethylacetate
DTXCID106796
CHEMBL3182130
2-Propyl, 1-methoxy-, acetate
HSDB 8443
LLHKCFNBLRBOGN-UHFFFAOYSA-
NSC2207
propyleneglycol methyl ether acetate
Tox21_201436
2-Propanol, 1-metoxi-, 2-acetato
AKOS015837930
Glycol Ether PM Acetate Reagent Grade
METHOXYISOPROPYL ACETATE [INCI]
NCGC00249046-01
NCGC00258987-01
142300-82-1
CAS-108-65-6
FT-0675939
P1171
1,2-Propanediol 1-Monomethyl Ether 2-Acetate
1,2-Propanediol monomethyl ether acetate, 99%
Propylene glycol monomethyl ether acetate, 99%
Actate de l'ther monomthylique du propylne glycol
EN300-1725866
J-504836
Q2170375
Propylene glycol monomethyl ether acetate, >=99.0% (GC)
Propylene glycol monomethyl ether acetate, ReagentPlus(R), >=99.5%
Propylene glycol monomethyl ether acetate, Vetec(TM) reagent grade
Propylene glycol 1-methyl ether 2-acetate 100 microg/mL in Acetonitrile
Propylene glycol monomethyl ether acetate; (1-Methoxypropyl-2-acetate)
METHYL PYRROLIDONE ( N-methyl-2-pyrrolidone) NMP
1,1'-sulfonylbis-methane; DMSO2;MSM; NSC 63345; CAS NO. 67-71-0
Methyl salicylate
Synthetic Wintergreen Oil; Methyl Hydroxybenzoate; Betula Oil; O-hydroxybenzoic Acid Methyl Ester; Gaultheria Oil; Methyl Sweet Birch Oil; O-hydroxybenzoate; 2-(Methoxycarbonyl)Phenol; 2-carbomethoxyphenol; Linsal; Methylester Kyseliny Salicylove (Czech); Salicylic Acid, Methyl Ester; o-Anisic acid CAS NO: 119-36-8
METHYL SILICONATE
DESCRIPTION:
Methyl siliconate is an aqueous solution of methyl Siliconate, water dilutable having slightly yellowish appearance used for the impregnation of mineral construction materials to make them water-repellent without significantly reducing water vapor permeability.
Methyl siliconate provides its water repellent properties by reaction with atmospheric carbon dioxide.
Treatment with Methyl siliconate prevents efflorescence of salts absorbed and makes cleaning of the tiled floor easier and Low fired clay products such as roof tiles, bricks, unglazed floor tiles absorb water and the soluble salts are transported to the surface, disfiguring the product.

CAS No.: 31795-24-1
EINECS No: 250-807-9

CHEMICAL AND PHYSICAL PROPERTIES OF METHYL SILICONATE:
Color and Appearance: Colorless Clear Liquid
Solid Contents: 40-45%
Active Substance: 25-28%
pH Value: 12~13
Density 25/25°C: 1.25~1.29


FEATURES OF METHYL SILICONATE:
• Methyl siliconate Imparts water repellency to a wide variety of substances.
• Methyl siliconate Reduces water absorption into the substrate, thus reducing spilling due to freeze-thaw and efflorescence, thereby increasing the life of the substrate.
• Methyl siliconate is Colorless and non-yellowing protection preserves the natural appearance of the substrate.

• Methyl siliconate Penetrating and breathable.
• Methyl siliconate has Low VOC.
• Methyl siliconate is Nonflammable.

• Methyl siliconate Cures with atmospheric CO2
• Methyl siliconate is Colorless, preserves the natural appearance of the substrate
• Methyl siliconate Forms potassium carbonate as side products
• Methyl siliconate is Suitable for thin and less damp walls

BENEFITS OF METHYL SILICONATE:
Treatment with methylsiliconate prevents efflorescence of salts absorbed and makes cleaning of the tiled floor easier.
Low fired clay products such as roof tiles, bricks, unglazed floor tiles absorb water and the soluble salts are transported to the surface, disfiguring the product.
Damage caused to the wet substrate/ clay product due to growth of moss, lichen and algae is also a common problem spoiling the beauty of the facade.

All the above phenomena are observed only if the masonry surface remains wet.
They will be eliminated if one can prevent or at least reduce water absorption.
Water resistance is an important factor in concrete and masonry construction for safety, health and comfort of building occupants.
As with all siliconates, Methyl siliconate can cause a white deposit on the surface of colored construction materials, or if used outside the application guidelines.

USABLE LIFE & STORAGE OF METHYL SILICONATE:
When stored bellow 45°C in the original unopened containers, Methyl siliconate has a usable life of 12 months from the date of manufacturing.
Methyl siliconate developed to impart water repellency to a wide variety of natural stone and masonry surfaces.
The siliconate reacts with carbon dioxide in the air to form an insoluble repellent surface and reduce water absorption within 24 hours.

Methyl siliconate sealer for concrete is suitable for the surface of natural stone, like sandstone, limestone, and red brick, gray brick, granite, ceramics etc.
Methyl siliconate is not suitable for polished or glazed surfaces.

Methyl siliconate is used to provide the surface of materials with excellent water resistance properties - the surface does not absorb water.

Methyl siliconate is used to make the material frost- and corrosion resistant.
Methyl siliconate is used to reduce the pollution of surface;
In addition, the treated surface does not change its appearance, maintains air permeability - material is not sweated and retains the ability to output pairs.

In addition, the treated surface does not change its appearance, maintains air permeability - material is not sweated and retains the ability to output pairs.
The liquid is methyl hydride siloxane polymer with low viscosity of light-yellow color or colorless.
Methyl siliconate is readily dissoluble in aromatic and chlorinated hydrocarbons, and is undergone to gelation in the presence of amines, amino alcohols, strong acids and alkalis.

No dissolution in lower alcohols and water.
The positive effects of the application of methyl hydride siloxane:

Improved water resistance of various building materials - water remains on the surface in the form of droplets and does not penetrate the material;
Methyl siliconate Increases frost resistance and improves thermal insulation materials;
Methyl siliconate Does not prevent air exchange – the construction outputs pair outside and does not accumulate moisture;
Methyl siliconate Prevents UV and infrared radiation;

Methyl siliconate Preserves the appearance of the material;
Methyl siliconate Extends the service life of materials;
Methyl siliconate Prevents surface mosses and lichens.

Water emulsion of organo silicon the methyl hydride siloxane with additives of emulsifier, biocides and stabilizers Solids content in the emulsion SE 50-94M is 50%.
The color is from white to light gray.

APPLICATION OF METHYL SILICONATE:
Metal manufacture: binding agent in the manufacture of ceramic molds for precision core-mold casting; manufacture of rods exposed to high temperatures; manufacture of non-stick paints
Textile industry: feltproofing of woolen cloths; abatement of carpet shrinkage; antirot and antidust protection of carpets; impregnating compound for filter cloths

Construction engineering: hydrophobization of construction materials, treatment of coated surfaces; porosity decreasing impregnation of concrete; manufacture of acid-resistant cement
Glasswork and cerarnics: antireflection treatment of optical glass; application of light-diffusing coat to electric light bulbs; binding agent for ceramic mixtures, resistant to strongly corrosive mediums, with high manufacture of fireproof material standing temperatures of about 1750 °C and stress of above 127 kg/cm3
Coating industry: paint additives forming quick-drying, thermostable and water-resistant coats with constant gloss.

Methyl siliconate is used in Surface treatment for porous building materials such as bricks, roof tiles, flower pots,etc.
Methyl siliconate is used as Admixture for concrete and mortars, coatings
Methyl siliconate is used as damp roofing agents

USES OF METHYL SILICONATE:
The emulsion oligo methyl hydride siloxane has properties and characteristics similar with the methyl hydride siloxane.
The emulsion is also used to provide various materials with water repellency properties.
However, as oligo methyl hydride siloxane is the water emulsion, it can be applied as an additive in the production of solutions and mixtures that is by the volumetric method.

Methyl siliconate is used for concrete, asbestos, gypsum, ceramic, porcelain
Methyl siliconate is used in the production of waterproof papers and leather;
Methyl siliconate is used in the production of water-resistant fabrics;

Methyl siliconate is used by volumetric method in the manufacture of paving tiles, slabs, curbs, fences of different silicate materials;
Methyl siliconate is used as plasticizer in the preparation of plaster, lime and cement solutions;
Methyl siliconate is used as an air involving admixture in the preparation of cement solution
Methyl siliconate is a mixture of tetra ethoxy silane and polyethoxy siloxanes.

Methyl siliconate is an aqueous solution and used in diluted form for the hydrophobic impregnation of mineral construction materials to make them water-repellent.
Methyl siliconate develops its water-repellent properties by reaction with atmospheric carbon dioxide (CO2).
The active substance formed from the silicone masonry water repellent is polymethylsilicic acid.

As with all siliconates, however, Methyl siliconate can cause a white deposit on the surface of colored construction materials, or if used outside the application guidelines.


CHEMISTRY OF METHYL SILICONATE:
Commercially available siliconates include potassium methyl siliconate (CAS 31795-24-1, CH5KO3Si) and sodium methyl siliconate (CAS 16589-43-8, CH5NaO3Si).
These are supplied as a concentrate in water with an active content of between 30 to 40% by weight.
This solution is further diluted in water prior to their application by spraying, dipping or rolling to a mineral building material, such as brickwork, to make the surface water repellent.

The dilution is clear, stable with a high pH of 13 to 14.
When applied to a surface the siliconate reacts with carbon dioxide in the air to form an insoluble water resistant treatment within 24 hours.
CH5KO3Si + silanol functional substrate OHSi → CH4O3Si + KOH

The methyl group has now attached itself to the substrata.
2KOH + CO2 → K2CO3 + H2O
The salts formed by this reaction are often the cause of white efflorescence when too much of the solution is applied to the surface.

ADVANTAGES OF METHYL SILICONATE IN CONSTRUCTION:
Methyl silicate needs to be diluted with water when it is used.
Methyl silicate can be used for stone and bricks, ceramics, cement mortar, perlite, gypsum and fiber gypsum board, and other materials, especially porous materials.
Methyl silicate Can produce surface waterproof and reduce moisture absorption.

Methyl silicate is permeable and absorbable and can maintain the natural appearance of the substrate without changing the original color and appearance of the substrate.
Methyl silicate can react with carbon dioxide in the air or other acidic compounds to form a surface layer on the substrate.
The insoluble mesh waterproof and breathable membrane has excellent waterproof effect and anti-seepage, moisture-proof, dust-proof, anti-aging, anti-pollution, and other advantages.

Methyl silicate prevents moisture from being absorbed into the substrate, thereby reducing the peeling caused by freeze-thaw and weathering, and increasing the life of the substrate.
The most important thing is to be simple and easy to operate in terms of construction.
Before construction, clean the surface of the substrate.

If there are cracks, fill it with putty or cement slurry, and then slightly moisten the surface of the substrate for absorption, and the entire project is cost-effective and resistant.
Abrasion, scrubbing resistance, high and low-temperature resistance, it can be seen that its performance is superior.


SAFETY INFORMATION ABOUT METHYL SILICONATE:

First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.

SYNONYMS OF METHYL SILICONATE:
potassium methylsilanetriolate
Silanetriol, methyl-, potassium salt
methyl-silanetrio potassium salt
Methylsilanetriol, potassium salt
potassium methylsiliconate solution
potassium methylsiliconate,40% in water
Methylsilanetriol/potassium,(1:x) salt;
Penta 811
potassium methylsilanetriolate
Potassium methyl siliconate
Potassium siliconate
DC 772
KZh 11
HSL 11
GKZh 11
Dryseal C
722 Water repellent
Sodium methylsilicate
Potassium methyl silic
SODIUM METHYLSILICONATE
methyl-silanetriosodiumsalt





METHYL SOYATE (SOYBEAN OIL METHYL ESTER)

Methyl soyate, also known as soybean oil methyl ester, is a chemical compound derived from soybean oil through a process called transesterification.
Transesterification involves reacting a triglyceride (in this case, soybean oil) with an alcohol (methanol) to produce fatty acid methyl esters (FAME), commonly known as biodiesel.
Methyl soyate (soybean oil methyl ester) is one of the resulting methyl esters.

CAS Number: 67784-80-9
EC Number: 267-055-2

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APPLICATIONS


Methyl soyate (soybean oil methyl ester) is widely used as a biodiesel fuel, offering a sustainable alternative to traditional diesel derived from fossil fuels.
Its primary application lies in the transportation sector, where it serves as a renewable and cleaner-burning fuel for diesel engines.

Methyl soyate (soybean oil methyl ester) is employed as a blending component in diesel fuel formulations to enhance their biocontent and reduce environmental impact.
In the agricultural industry, it finds application in formulations for crop protection products, acting as a carrier or solvent.
Its use in pesticide formulations aligns with environmentally conscious agricultural practices due to its biodegradability and low toxicity.

Methyl soyate (soybean oil methyl ester) is utilized in the formulation of eco-friendly cleaning products, providing a safer and sustainable alternative to conventional solvents.
As a solvent, Methyl soyate (soybean oil methyl ester) is effective in removing greases, oils, and other contaminants from surfaces in industrial and household cleaning applications.
Methyl soyate (soybean oil methyl ester) serves as a lubricity improver, enhancing the lubricating properties of certain engine oils and industrial lubricants.
Methyl soyate (soybean oil methyl ester) is an ingredient in hydraulic fluids, contributing to the development of more environmentally friendly formulations.

Due to its low volatility and flash point, it is utilized safely in the formulation of certain industrial fluids and lubricants.
In the cosmetic and personal care industry, methyl soyate can be found in formulations for skin and hair care products.

Its excellent solvency properties make methyl soyate suitable for use in the formulation of paint and coating removers.
Methyl soyate (soybean oil methyl ester) is employed as a component in ink formulations, contributing to the development of more sustainable printing solutions.
The renewable nature of methyl soyate aligns with the development of environmentally friendly and biodegradable adhesives.

In the construction industry, it finds use in formulations for environmentally conscious concrete release agents.
Methyl soyate (soybean oil methyl ester) acts as a carrier in the formulation of certain fragrance and flavor products.
Due to its low toxicity, it is considered a preferable ingredient in certain formulations for eco-friendly insecticides.

Methyl soyate (soybean oil methyl ester) is utilized in the development of bio-based and sustainable asphalt release agents.
Methyl soyate (soybean oil methyl ester) is employed as a key component in formulations for environmentally friendly graffiti removers.
Its compatibility with a variety of materials makes it valuable in the formulation of eco-friendly degreasers.

Methyl soyate (soybean oil methyl ester) is utilized in the production of environmentally conscious metalworking fluids and lubricants.
In the textile industry, it serves as a solvent in formulations for eco-friendly textile dyeing processes.

Methyl soyate (soybean oil methyl ester) is used in the formulation of biodegradable and sustainable fuel additives.
Its application extends to the production of eco-friendly and bio-based transformer oils.
Methyl soyate (soybean oil methyl ester)'s versatility in various formulations contributes to the development of environmentally responsible and sustainable products across multiple industries.

Methyl soyate (soybean oil methyl ester) is utilized as a feedstock in the production of bioplastics, contributing to the development of sustainable packaging materials.
In the pharmaceutical industry, it is explored for potential applications in drug delivery systems due to its biocompatibility and renewable nature.

Methyl soyate (soybean oil methyl ester) serves as a key ingredient in the formulation of environmentally friendly and bio-based paint and coating solutions.
As a renewable and biodegradable ingredient, it is used in the production of eco-friendly household cleaning sprays and wipes.

Methyl soyate (soybean oil methyl ester) acts as a carrier solvent in the development of green and sustainable ink formulations for printing.
Methyl soyate (soybean oil methyl ester) finds applications in the creation of environmentally conscious and bio-based resin systems for composite materials.

Methyl soyate (soybean oil methyl ester) is used as a degreasing agent in automotive and industrial maintenance applications.
In the manufacturing of biodegradable and eco-friendly candles, it serves as a component in certain wax formulations.
Methyl soyate (soybean oil methyl ester) contributes to the formulation of sustainable and bio-based asphalt rejuvenators for road maintenance.
Methyl soyate (soybean oil methyl ester) is explored for its potential use in the development of bio-based and green pesticides for agricultural practices.

As a bio-based alternative, it is considered in the production of sustainable and non-toxic wood preservatives.
Methyl soyate (soybean oil methyl ester) is used in the formulation of environmentally friendly and biodegradable lubricants for industrial machinery.
Methyl soyate (soybean oil methyl ester) serves as a component in the creation of sustainable and biodegradable surfactants for cleaning products.

Methyl soyate (soybean oil methyl ester) is employed in the formulation of eco-friendly and biodegradable air fresheners and deodorizers.
In the automotive industry, Methyl soyate (soybean oil methyl ester) is considered as a component in the production of environmentally conscious and bio-based car care products.
Methyl soyate (soybean oil methyl ester) acts as a carrier solvent in the development of eco-friendly and bio-based adhesive formulations.
Methyl soyate (soybean oil methyl ester) is used as a base fluid in the formulation of biodegradable and sustainable cutting fluids for metalworking applications.

Methyl soyate (soybean oil methyl ester) is explored as a potential component in the formulation of sustainable and bio-based personal care products.
In the agricultural sector, it is considered for the creation of bio-based and eco-friendly plant protection products.
Methyl soyate (soybean oil methyl ester) serves as a component in the formulation of sustainable and biodegradable leather finishing agents.

Methyl soyate (soybean oil methyl ester) is explored for its potential use in the development of eco-friendly and bio-based corrosion inhibitors.
Methyl soyate (soybean oil methyl ester) is utilized in the creation of bio-based and sustainable ink removers and cleaning solutions.
In the formulation of bio-based and eco-friendly refrigeration lubricants, it serves as a key ingredient.

Methyl soyate (soybean oil methyl ester) finds applications in the creation of sustainable and bio-based carpet cleaning solutions.
As a renewable and biodegradable fuel, it contributes to the development of sustainable and green energy solutions for transportation and industrial applications.

Methyl soyate is employed in the formulation of eco-friendly and bio-based rust inhibitors for metal protection.
As a sustainable alternative, it is utilized in the creation of biodegradable and non-toxic graffiti removers.
Methyl soyate finds application as a key ingredient in the production of environmentally friendly and bio-based tire shines.
In the manufacturing of bio-based and green sealants, it acts as a versatile and sustainable base component.

The renewable nature of methyl soyate is harnessed in the creation of bio-based and biodegradable hydraulic fluids.
Methyl soyate (soybean oil methyl ester) is used in the formulation of sustainable and eco-friendly concrete form release agents.
Methyl soyate (soybean oil methyl ester) serves as a valuable component in the production of bio-based and non-toxic wood stain and finishes.

Methyl soyate (soybean oil methyl ester) contributes to the development of bio-based and sustainable metal cleaning and polishing agents.
In the formulation of bio-based and eco-friendly carpet stain removers, it acts as an effective cleaning agent.
Methyl soyate (soybean oil methyl ester) is explored as a potential component in the creation of environmentally friendly and green insect repellents.

Methyl soyate (soybean oil methyl ester) serves as a carrier solvent in the formulation of sustainable and bio-based inkjet printer inks.
Methyl soyate (soybean oil methyl ester) finds application in the creation of bio-based and non-hazardous mold release agents.

In the manufacturing of bio-based and eco-friendly air filter cleaning solutions, it acts as a cleaning agent.
Methyl soyate (soybean oil methyl ester) is used as a key component in the formulation of bio-based and non-toxic degreasers.
As a renewable and biodegradable fuel, it contributes to the development of bio-based marine lubricants.
Methyl soyate (soybean oil methyl ester) serves as a sustainable alternative in the formulation of bio-based and green metal coatings.

In the creation of sustainable and eco-friendly bathroom cleaners, it acts as a powerful cleaning agent.
Methyl soyate (soybean oil methyl ester) is utilized in the production of bio-based and environmentally friendly mold and mildew removers.
Methyl soyate (soybean oil methyl ester) finds applications in the formulation of sustainable and non-toxic driveway and patio cleaners.

Methyl soyate (soybean oil methyl ester) contributes to the creation of bio-based and green industrial hand cleaners and degreasers.
In the formulation of eco-friendly and bio-based automotive appearance products, it acts as a key ingredient.

Methyl soyate (soybean oil methyl ester) is explored as a potential component in the development of bio-based and non-toxic herbicides.
Methyl soyate (soybean oil methyl ester) serves as a carrier solvent in the creation of sustainable and environmentally friendly aerosol products.

Methyl soyate (soybean oil methyl ester) is used in the production of bio-based and biodegradable anti-corrosion coatings.
As a versatile and sustainable ingredient, it contributes to the development of bio-based and non-toxic specialty cleaning products.



DESCRIPTION


Methyl soyate, also known as soybean oil methyl ester, is a chemical compound derived from soybean oil through a process called transesterification.
Transesterification involves reacting a triglyceride (in this case, soybean oil) with an alcohol (methanol) to produce fatty acid methyl esters (FAME), commonly known as biodiesel.
Methyl soyate (soybean oil methyl ester) is one of the resulting methyl esters.

Methyl soyate (soybean oil methyl ester) is a biodiesel derived from soybean oil through transesterification.
Methyl soyate (soybean oil methyl ester) is produced by reacting soybean oil with methanol to form fatty acid methyl esters.

As a clean and sustainable alternative, methyl soyate reduces reliance on traditional petroleum-based diesel.
Its composition mainly comprises fatty acid methyl esters, making it environmentally friendly.
Methyl soyate (soybean oil methyl ester) is recognized for its biodegradability, contributing to lower environmental impact.

Methyl soyate (soybean oil methyl ester) exhibits low volatility and emits fewer greenhouse gases compared to conventional diesel.
Methyl soyate (soybean oil methyl ester) is a key player in the move towards more sustainable and eco-friendly transportation solutions.
Methyl soyate (soybean oil methyl ester) serves as a versatile component in various industrial applications beyond biodiesel fuel.

As a solvent, it is employed in cleaning products, providing a safer alternative to traditional solvents.
Methyl soyate (soybean oil methyl ester) offers improved lubricity, making it suitable for certain industrial lubricants.
In agriculture, methyl soyate finds use in formulations for crop protection products.
Its low toxicity and biodegradability make methyl soyate a preferable choice in certain pesticide formulations.

Methyl soyate (soybean oil methyl ester) is known for its excellent solvency, making it effective in removing grease and oils.
Methyl soyate (soybean oil methyl ester) has a high flash point, contributing to its safety in handling and storage.
The esterification process results in a product with enhanced stability and resistance to degradation.

Methyl soyate (soybean oil methyl ester) exhibits good compatibility with a range of materials, making it suitable for various formulations.
Due to its renewable nature, methyl soyate plays a role in reducing dependence on finite fossil fuels.
As a lubricity improver, it enhances the performance of certain engine oils and lubricants.

Methyl soyate (soybean oil methyl ester) is a preferred choice in applications where reducing volatile organic compound (VOC) emissions is essential.
Its neutral odor and color make methyl soyate suitable for applications where sensory properties are critical.
Methyl soyate (soybean oil methyl ester)'s biodegradability extends to its use in certain eco-friendly hydraulic fluids.
Methyl soyate (soybean oil methyl ester) contributes to the reduction of sulfur and aromatics in comparison to traditional diesel.

Methyl soyate (soybean oil methyl ester)'s multifunctional nature makes it an attractive ingredient in the formulation of diverse consumer products.
Methyl soyate (soybean oil methyl ester) aligns with sustainability goals in both the transportation and industrial sectors.
Methyl soyate (soybean oil methyl ester) stands out as a bio-based solution, embodying the principles of environmental responsibility and resource efficiency.



PROPERTIES


Acid Value: 3 MAX
Saponification Value: 182 – 195
Iodine Value: 113 – 140
Moisture: 0.75% Max by KFR



FIRST AID


Inhalation:

Move to Fresh Air:
If inhaled, promptly move the affected person to an area with fresh air.

Rest and Seek Medical Attention:
If respiratory irritation persists, provide rest and seek medical attention.


Skin Contact:

Remove Contaminated Clothing:
Remove contaminated clothing promptly.

Wash Skin:
Wash the affected skin area thoroughly with soap and water.

Seek Medical Attention:
If irritation persists or if the chemical is absorbed through the skin, seek medical attention.


Eye Contact:

Flush Eyes:
Immediately flush the eyes with gently flowing water for at least 15 minutes, lifting the upper and lower eyelids.

Seek Medical Attention:
Seek immediate medical attention if irritation or symptoms persist.


Ingestion:

Do Not Induce Vomiting:
Do not induce vomiting unless instructed to do so by medical personnel.

Rinse Mouth:
Rinse the mouth with water if the person is conscious.

Seek Medical Attention:
Seek immediate medical attention.


General First Aid Tips:

Keep Person Calm:
Keep the affected person calm to reduce stress and anxiety.

Do Not Ignore Symptoms:
Even if symptoms appear minor, it's essential not to ignore them.
Seek medical attention if there is any doubt about the severity of exposure.

Personal Protection:
Wear appropriate personal protective equipment (PPE) during first aid interventions to avoid exposure.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including gloves and safety glasses, to minimize skin contact and eye exposure.
Use suitable protective clothing to prevent prolonged or repeated skin contact.

Ventilation:
Use the product in a well-ventilated area to control airborne concentrations.
Consider local exhaust ventilation if necessary.

Avoid Contamination:
Prevent contamination by using clean tools, utensils, and equipment.
Avoid contact with incompatible materials, and follow proper procedures to prevent cross-contamination.

Hygiene Practices:
Implement good personal hygiene practices, including regular handwashing, to minimize the risk of accidental ingestion or contact.

Spill and Leak Procedures:
Clean up spills promptly using appropriate absorbent materials.
Avoid creating dust or aerosols during cleanup.
Use vacuum systems or wet methods if possible.

Temperature Control:
Store and handle the product within specified temperature ranges as indicated in the SDS.

Grounding and Bonding:
Use proper grounding and bonding procedures to prevent static electricity buildup.


Storage:

Containers:
Store methyl soyate in approved containers made of materials compatible with the product.
Keep containers tightly closed when not in use to prevent contamination and evaporation.

Segregation:
Store methyl soyate away from incompatible substances, including strong acids, bases, and oxidizing agents.

Labeling:
Ensure containers are properly labeled with the product name, hazard information, and any specific storage instructions.

Fire Prevention:
Take measures to prevent and control fire hazards in storage areas.
Follow fire protection guidelines provided in the SDS.

Ventilation:
Maintain good ventilation in storage areas to prevent the buildup of vapors.
Store in well-ventilated areas away from incompatible materials.

Controlled Environment:
If specified by the manufacturer, store the product in a controlled environment with specific temperature and humidity conditions.

Inventory Management:
Follow a first-in, first-out (FIFO) inventory management system to ensure older stock is used first.

Security Measures:
Implement appropriate security measures to prevent unauthorized access to storage areas.

METHYL SOYATE (SOYBEAN OIL METHYL ESTER)

Methyl soyate, also known as soybean oil methyl ester, is a chemical compound derived from soybean oil through a process known as transesterification.
Methyl soyate (Soybean oil methyl ester) is classified as a fatty acid methyl ester (FAME) and is a type of biodiesel.
Methyl soyate (Soybean oil methyl ester) consists of methyl esters of fatty acids found in soybean oil, making it a renewable and biodegradable alternative to traditional petroleum-based fuels and solvents.
Its chemical structure consists of the methyl esters of various fatty acids present in soybean oil, such as oleic acid, linoleic acid, and stearic acid.



APPLICATIONS


Methyl soyate (Soybean oil methyl ester) has various applications:

Biodiesel Production:
Methyl soyate (Soybean oil methyl ester) is commonly used as a key ingredient in the production of biodiesel, serving as a renewable and eco-friendly alternative to traditional diesel fuel.

Diesel Engine Fuel:
Methyl soyate (Soybean oil methyl ester) can be blended with petroleum diesel and used as a fuel in diesel engines, reducing greenhouse gas emissions and air pollution.

Eco-Friendly Solvent:
Methyl soyate (Soybean oil methyl ester) is employed as a natural and sustainable solvent in various industries, including printing, coatings, and paints.

Ink Formulations:
Methyl soyate (Soybean oil methyl ester) is a component in eco-friendly ink formulations, contributing to reduced volatile organic compound (VOC) emissions.

Paint and Coatings:
Methyl soyate (Soybean oil methyl ester) can be found in environmentally friendly paints and coatings, offering lower toxicity and reduced environmental impact.

Cleaning Products:
Methyl soyate (Soybean oil methyl ester) is used in the formulation of eco-friendly cleaning agents, such as degreasers, graffiti removers, and household cleaners.

Agricultural Applications:
Methyl soyate (Soybean oil methyl ester) serves as an ingredient in herbicides, insecticides, and fungicides, promoting sustainability in agriculture.

Pesticide Formulations:
Methyl soyate (Soybean oil methyl ester) is used as a carrier or diluent for active ingredients in pesticide formulations, enhancing their effectiveness.

Adjuvants:
Methyl soyate (Soybean oil methyl ester) is utilized as an adjuvant to improve the performance of agricultural chemicals.

Lubricants:
In industrial applications, Methyl soyate (Soybean oil methyl ester) serves as a lubricant, offering excellent lubricity and biodegradability.

Hydraulic Fluids:
Methyl soyate (Soybean oil methyl ester) is a component in the production of environmentally friendly hydraulic fluids, suitable for various machinery.

Cosmetics and Personal Care:
Methyl soyate (Soybean oil methyl ester) is used in cosmetics and personal care products, including skin creams and hair care items, as a natural ingredient.

Aromatherapy:
Methyl soyate (Soybean oil methyl ester) serves as a carrier oil for essential oils in aromatherapy practices.

Adhesives:
Methyl soyate (Soybean oil methyl ester) is used in the formulation of eco-friendly adhesives, contributing to reduced VOC emissions.

Textile Industry:
Methyl soyate (Soybean oil methyl ester) can be used as a cleaner and degreaser in the textile industry.

Automotive Care Products:
Methyl soyate (Soybean oil methyl ester) is found in eco-friendly automotive care products, including degreasers, tire shine, and interior cleaners.

Metalworking Fluids:
Methyl soyate (Soybean oil methyl ester) is used as an eco-friendly alternative in metalworking fluids, such as cutting oils and rust preventatives.

Plastics and Composites:
Methyl soyate (Soybean oil methyl ester) can be employed as a mold release agent in plastics and composites manufacturing.

Biodegradable Penetrating Oils:
Methyl soyate-based penetrating oils are used in mechanical applications for loosening rusted or stuck components.

Paint Strippers:
Eco-friendly paint strippers containing methyl soyate are available for removing paint coatings.

Surface Coatings:
Methyl soyate (Soybean oil methyl ester) is used in eco-friendly surface coatings for wood, metal, and concrete substrates.

Electronics Cleaning:
Methyl soyate-based cleaners are used in electronics manufacturing for residue and flux removal.

Printing Ink Cleaners:
Methyl soyate (Soybean oil methyl ester) serves as an effective cleaner for printing presses and ink-related equipment.

Bio-Based Fuel Additives:
Methyl soyate (Soybean oil methyl ester) can be added to conventional fuels as a bio-based additive to improve combustion properties.

Environmental Remediation:
Methyl soyate (Soybean oil methyl ester) is used in environmental remediation processes for cleaning up oil spills and contaminated sites, offering a sustainable solution.

Furniture Polishes:
Methyl soyate (Soybean oil methyl ester) is used in the formulation of eco-friendly furniture polishes, providing a natural shine to wood surfaces.

Concrete Form Release Agents:
Methyl soyate (Soybean oil methyl ester) serves as a bio-based release agent for concrete forms, ensuring easy removal and reducing the need for chemical release agents.

Rubber Manufacturing:
In the rubber industry, Methyl soyate (Soybean oil methyl ester) is employed as a processing aid and lubricant during tire and rubber product manufacturing.

Firefighting Foams:
Methyl soyate (Soybean oil methyl ester) is used in the production of environmentally friendly firefighting foams with reduced environmental impact.

Eco-Friendly Insect Repellents:
Some insect repellent formulations incorporate Methyl soyate as a bio-based and less toxic alternative.

Marine Applications:
Methyl soyate (Soybean oil methyl ester) can be used in marine engine applications, contributing to cleaner emissions in maritime transport.

Graffiti Removal:
Methyl soyate (Soybean oil methyl ester) is effective in graffiti removal products, offering a safer and more sustainable solution for urban maintenance.

Paper Coatings:
Methyl soyate (Soybean oil methyl ester) is used in paper coatings to enhance printability and reduce the environmental footprint of paper products.

Wax Products:
Methyl soyate (Soybean oil methyl ester) is an ingredient in eco-friendly wax products, including candles, providing a clean-burning option.

Firelighters:
Some firelighter products utilize Methyl soyate as a bio-based ignition source for fires.



DESCRIPTION


Methyl soyate, also known as soybean oil methyl ester, is a chemical compound derived from soybean oil through a process known as transesterification.
Methyl soyate (Soybean oil methyl ester) is classified as a fatty acid methyl ester (FAME) and is a type of biodiesel.
Methyl soyate (Soybean oil methyl ester) consists of methyl esters of fatty acids found in soybean oil, making it a renewable and biodegradable alternative to traditional petroleum-based fuels and solvents.
Its chemical structure consists of the methyl esters of various fatty acids present in soybean oil, such as oleic acid, linoleic acid, and stearic acid.
The transesterification process involves reacting soybean oil with methanol, resulting in the production of methyl soyate and glycerol as a byproduct.

Methyl soyate has gained attention as a more environmentally friendly and sustainable option for various applications, including as a biodiesel fuel, solvent, and ingredient in cleaning products.
Methyl soyate (Soybean oil methyl ester) is known for its low toxicity, biodegradability, and reduced greenhouse gas emissions compared to conventional fossil fuels.

Methyl soyate (Soybean oil methyl ester) is a renewable and biodegradable chemical compound.
Methyl soyate (Soybean oil methyl ester) is derived from soybean oil through a process known as transesterification.
The primary component of methyl soyate is the methyl esters of fatty acids found in soybean oil.

Methyl soyate (Soybean oil methyl ester) is considered a type of biodiesel, often used as a sustainable alternative to conventional diesel fuel.
The transesterification process involves reacting soybean oil with methanol or ethanol to produce methyl soyate and glycerol.
Methyl soyate (Soybean oil methyl ester) is known for its eco-friendly properties, as it is biodegradable and has lower emissions compared to fossil fuels.

Methyl soyate (Soybean oil methyl ester) has gained popularity in recent years due to its potential to reduce greenhouse gas emissions.
Methyl soyate (Soybean oil methyl ester) is a clear and colorless liquid with a mild, characteristic odor.
Methyl soyate can be used as a solvent in various applications, such as inks, paints, coatings, and cleaning products.



PROPERTIES


Chemical Formula: Methyl soyate is a mixture of methyl esters of fatty acids found in soybean oil, and its chemical composition varies based on the source and production process.
Molecular Weight: The molecular weight of Methyl soyate can vary depending on the specific fatty acid methyl esters present in the mixture.
Appearance: It is typically a clear and colorless liquid.
Odor: Methyl soyate has a mild, characteristic odor.
Density: The density of Methyl soyate is approximately 0.90 to 0.92 g/cm³ at 20°C (68°F).
Boiling Point: The boiling point of Methyl soyate can range between approximately 210°C to 300°C (410°F to 572°F) due to the mixture's composition.
Melting Point: Methyl soyate does not have a distinct melting point as it is a liquid at room temperature.
Solubility: It is soluble in various organic solvents, such as ethanol and acetone, but its solubility in water is limited.
Flash Point: The flash point of Methyl soyate is typically above 150°C (302°F), making it relatively safe for storage and handling.



FIRST AID


Inhalation:

Move to Fresh Air:
If someone inhales Methyl soyate fumes or vapors and experiences respiratory discomfort, immediately move them to an area with fresh air.

Provide Oxygen:
If breathing difficulties persist, provide oxygen support if available, and seek medical attention promptly.


Skin Contact:

Remove Contaminated Clothing:
If Methyl soyate comes into contact with the skin, promptly remove contaminated clothing and shoes to prevent further exposure.

Wash Skin Thoroughly:
Wash the affected skin area with soap and plenty of running water for at least 15 minutes to remove any residual chemical.

Seek Medical Attention:
If skin irritation, redness, or other adverse reactions occur, seek medical attention.


Eye Contact:

Flush Eyes:
In case of eye contact with Methyl soyate, immediately flush the eyes with gently flowing lukewarm water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.

Seek Medical Attention:
If eye irritation, redness, or pain persists after rinsing, seek immediate medical attention.


Ingestion:

Do Not Induce Vomiting:
If Methyl soyate is ingested accidentally, DO NOT induce vomiting.
This can lead to aspiration of the chemical into the lungs.

Rinse Mouth:
If the person is conscious and alert, rinse their mouth with water but do not swallow.

Seek Medical Attention:
Immediately seek medical assistance or contact a poison control center for guidance.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
When handling Methyl soyate (Soybean oil methyl ester), wear appropriate PPE, including chemical-resistant gloves, safety goggles or face shield, and protective clothing to minimize skin and eye contact.

Ventilation:
Use Methyl soyate (Soybean oil methyl ester) in a well-ventilated area to minimize inhalation exposure.
If working in enclosed spaces, use local exhaust ventilation or wear a respiratory protection device suitable for organic vapors if necessary.

Avoid Open Flames and Sparks:
Methyl soyate (Soybean oil methyl ester) is flammable.
Keep it away from open flames, sparks, and heat sources. Use explosion-proof electrical equipment in areas where flammable vapors may be present.

Static Electricity:
Prevent the buildup of static electricity by grounding all equipment and containers during transfer and handling.

Smoking and Eating:
Do not smoke, eat, or drink while handling Methyl soyate, as it may lead to accidental ingestion or inhalation.

Chemical Compatibility:
Be aware of chemical compatibility when using Methyl soyate.
Avoid contact with strong acids, strong bases, and reactive chemicals that may cause undesirable reactions.

Spill Response:
Have spill response equipment and materials readily available, including absorbent materials and spill containment devices.
In the event of a spill, follow proper cleanup procedures to prevent environmental contamination.

Storage Temperature:
Store Methyl soyate in a cool, dry, and well-ventilated area.
Maintain storage temperatures within the recommended range specified by the manufacturer to prevent degradation.


Storage:

Containers:
Store Methyl soyate in tightly sealed containers made of materials compatible with the chemical, such as high-density polyethylene (HDPE) or stainless steel.

Labeling:
Clearly label all containers with the product name, hazard information, and safety precautions.

Segregation:
Store Methyl soyate away from incompatible substances, such as strong acids, strong bases, and oxidizers, to prevent chemical reactions.

Flammables:
Keep Methyl soyate away from other flammable materials and ignition sources.
Store it in a designated flammable liquids storage area.

Spill Containment:
Use spill containment measures, such as spill berms or trays, to prevent leaks or spills from spreading in case of container damage.

Fire Safety:
Store Methyl soyate away from fire hazards, and ensure that fire extinguishing equipment, such as fire extinguishers and fire blankets, is available and regularly maintained.

Temperature Control:
Avoid exposure to extreme temperatures. Keep containers out of direct sunlight and away from excessive heat sources.

Monitoring:
Regularly inspect containers for signs of damage, leaks, or corrosion. Replace damaged containers promptly.

Security:
Control access to storage areas to prevent unauthorized personnel from handling or accessing Methyl soyate.

Emergency Response:
Ensure that employees are trained in emergency response procedures, including spill cleanup and fire extinguishing techniques.



SYNONYMS


Soy Methyl Ester
Biodiesel Methyl Ester
Soy Methyl Ester Biodiesel
B100 (when referring to pure biodiesel)
Fatty Acid Methyl Ester (FAME)
Vegetable Oil Methyl Ester
Soy Biodiesel
Methylated Soybean Oil
Methyl Ester of Soybean Oil
Biodiesel from Soybean Oil
Soy Methylester Biodiesel
Methylated Soy Ester
Soy Methyl Ester Fuel
Methyl Soybeanate
Bio-Soy Methyl Ester
Soy Methyl Ester Fuel
Biodiesel Derived from Soybean Oil
Soy Oil Methyl Ester
Methyl Ester of Vegetable Oil
Biodiesel Made from Soybean Oil
Soy Methyl Ester Renewable Fuel
Soy Methanol Ester
Renewable Diesel from Soybean Oil
Soybean Oil Methylester
Methyl Esterified Soybean Oil
Soybean Biodiesel
Soy Methylester Diesel
Soybean Oil Ester
Methylated Soybean Ester
Vegetable Methyl Ester
Soybean Oil Methyl Ester Fuel
Soy Biodiesel Fuel
Soybean Oil Methylate
Soy-Based Biodiesel
Soy Methyl Ester Renewable Diesel
Biofuel from Soybean Oil
Soy Ester Biodiesel
Soy Oil Methyl Ester Renewable Fuel
Bio-Methyl Soy Ester
Methylated Soybean Oil Diesel
Biodiesel from Soybean Methyl Ester
Soy Esterified Oil
Soy Methanol Ester Fuel
Soy Methylate Renewable Fuel
Bio-Soy Diesel
Soybean Methyl Ester Biodiesel
Methyl Ester Fuel from Soy Oil
Renewable Diesel Made from Soy
Soybean-Based Renewable Fuel
Biodiesel Fuel Derived from Soy
Soybean Oil Methyl Ester
Soy Methylate Fuel
Methylated Soybean Oil Biodiesel
Soy Ester Renewable Diesel
Bio-Soy Methylate
Soy Methyl Ester Biofuel
Soybean Methylate Renewable Fuel
Biodiesel Fuel from Soy Methyl Ester
Methyl Soybean Ester Renewable Diesel
Soy Methanol Ester Biofuel
Soy Oil Methyl Ester Renewable Energy
B100 Diesel (when referring to pure biodiesel)
Soy Methylated Renewable Fuel
Methyl Ester of Soybean Oil for Energy
Soy Methyl Ester Sustainable Fuel
Soybean Oil Methanol Ester
Biodiesel Fuel Made from Soy Ester
Soy Methyl Ester Green Fuel
Renewable Diesel Derived from Soybean Ester
Soybean Oil Methylester Fuel
Methyl Soy Ester Energy Source
Bio-Methylated Soybean Ester
Soy Ester Biodiesel Renewable Energy
Biodiesel Fuel from Soy Methylate
Soy-Based Methyl Ester Renewable Diesel
METHYL SULFONYL METHANE
1,2,3,6-TETRAHYDRO-3-METHYLPHTHALIC ANHYDRIDE; 1,2,3,6-tetrahydro-4-methylphthalic anhydride; 1-METHYL-5-CYCLOHEXENE-2,3-DICARBOXYLIC ANHYDRIDE; 3a,4,7,7a-tetrahydromethyl-1,3-isobenzofurandione; 3-METHYL-4-CYCLOHEXEN-1,2-DICARBOXYLIC ANHYDRIDE; 3-METHYL-4-CYCLOHEXENE-1,2-DICARBOXYLIC ANHYDRIDE; 3-METHYL-DELTA4-TETRAHYDROPHTHALIC ANHYDRIDE; 3-METHYLTETRAHYDROPHTHALIC ANHYDRIDE 4-METHYL TETRAHYDROPHTHALIC ANHYDRIDE; AC-METHYL METHYL-1,2,3,6-TETRAHYDROPHTHALIC ANHYDRIDE; METHYLCYCLOHEXENE-1,2-DICARBOXYLIC ANHYDRIDE; METHYLTETRAHYDROPHTHALIC ANHYDRIDE; MTHPA MTHPA-600; MTHPA-EG; 3-Isobenzofurandione,tetrahydromethyl-1 tetrahydromethyl-3-isobenzofurandione; 1,3-Isobenzofurandione, tetrahydromethyl; tetrahydromethylphthalic anhydride CAS NO: 11070-44-3
METHYL TERT-BUTYL ETHER
Methyl tert-butyl ether is a volatile, flammable, and colorless liquid that is sparingly soluble in water.
The structure of Methyl tert-butyl ether consists of a methyl group (CH3) attached to a tertiary butyl group (t-butyl) with an oxygen atom in between.
Methyl tert-butyl ether is an organic compound classified as an ether.

CAS Number: 1634-04-4
Molecular Formula: C5H12O
Molecular Weight: 88.15
EINECS: 216-653-1

Methyl tert-Butyl Ether (MTBE) is a man-made chemical that raises the oxygen content of gasoline, allowing it to burn more cleanly in vehicles.
Methyl tert-butyl ether (MTBE), also known as methyl tert-butyl ether and tert-butyl methyl ether, is an organic compound with a structural formula (CH3)3COCH3.
Primarily used as a fuel additive, MTBE is blended into gasoline to increase its octane rating and knock resistance, and reduce unwanted emissions.

Methyl tert-butyl ether (MTBE) is a chemical compound with the molecular formula C5H12O.
Methyl tert-butyl ether is a clear, volatile liquid that is highly flammable.
It has a characteristic odor similar to that of diethyl ether.

Methyl tert-butyl ether was primarily used as a gasoline additive to enhance octane levels and improve the combustion properties of gasoline, thereby reducing engine knocking and improving overall engine performance.
Methyl tert-butyl ether was widely used in reformulated gasoline (RFG) to comply with environmental regulations aimed at reducing air pollution and smog formation.

Methyl tert-butyl ethers impact on groundwater contamination and potential health hazards led to its reduced use and eventual ban in some regions.
Methyl tert-butyl ether is known to be more soluble in water than many other gasoline components, making it a potential groundwater pollutant if gasoline containing Methyl tert-butyl ether leaks from storage tanks or spills occur.

Methyl tert-butyl ether, also known as MTBE or Methyl tert-butyl ether, is a clear, colorless liquid with a low viscosity that is combustible and has a distinct, turpentine-like odor.
It is miscible with organic solvents, but only slightly soluble in water.
Methyl tert-butyl ether is very stable under alkaline, neutral, and weakly acidic conditions.

In the presence of strong acids, Methyl tert-butyl ether is cleaved to methanol and isobutene.
Depending on reaction conditions the latter can form isobutene oligomers.
Methyl tert-butyl ether does not undergo autoxidation and, in contrast to other ethers, it does not form peroxides with atmospheric oxygen.

Methyl tert-butyl ether improves the antiknock properties when added to motor gasoline.
Methyl tert-butyl ether is manufactured via the chemical reaction of methanol and isobutylene.
Methanol is primarily derived from natural gas, where steam reforming converts the various light hydrocarbons in natural gas (primarily methane) into carbon monoxide and hydrogen.

The resulting gases then further react in the presence of a catalyst to form Methyl tert-butyl ether.
Isobutylene can be produced through a variety of methods.
n-butane can be isomerized into isobutane which can be dehydrogenated to isobutylene.

In the Halcon process, Methyl tert-butyl ether derived from isobutane oxygenation is reacted with propylene to produce propylene oxide and t-butanol.
The t-butanol can be dehydrated to isobutylene.
One of the primary reasons for using Methyl tert-butyl ether as a gasoline additive was its ability to boost the octane rating of gasoline.

Octane rating indicates a fuel's resistance to knocking or pre-ignition in internal combustion engines.
Higher octane ratings allow for higher engine compression ratios and improved performance.
Methyl tert-butyl ether has been a subject of environmental concern due to its potential to contaminate groundwater.

Methyl tert-butyl ethers high solubility in water makes it more likely to migrate into underground water sources in the event of gasoline leaks or spills.
Because of this, its use in gasoline has been significantly reduced or banned in many places.
In the 1990s and early 2000s, Methyl tert-butyl ether contamination of groundwater became a significant issue in some areas, particularly in the United States.

Leaks from underground gasoline storage tanks and accidental spills at gas stations were among the major sources of Methyl tert-butyl ether pollution in the environment.
Methyl tert-butyl ether is considered to have low acute toxicity to humans.
However, prolonged exposure to high levels of MTBE vapor or ingestion may cause health issues such as irritation of the respiratory system, skin, and eyes.

Methyl tert-butyl ether is also used in various industrial applications as a solvent in the production of chemicals, pharmaceuticals, and other products.
However, its use in these applications is generally more controlled compared to its use as a gasoline additive.
The regulations and legal status of Methyl tert-butyl ether vary from country to country.

Melting point: -110 °C
Boiling point: 55-56 °C(lit.)
Density: 0.7404
vapor density: 3.1 (vs air)
vapor pressure: 4.05 psi ( 20 °C)
refractive index: n20/D 1.369(lit.)
Flash point: -27 °F
storage temp.: Store at +2°C to +25°C.
solubility: 42g/l
form: Powder or Needles
color APHA: ≤10
Specific Gravity: 0.740
Odor: Characteristic ethereal odor
Relative polarity: 0.124
explosive limit: 1.5-8.5%(V)
Relative density, gas (air=1): 0.74 g/cm3 at 25 °C
Viscosity: 0.464mm2/s
Water Solubility: 51 g/L (20 ºC)
FreezingPoint: -108.6℃
λmax: λ: 210 nm Amax: 1.0
λ: 225 nm Amax: 0.50
λ: 250 nm Amax: 0.10
λ: 300-400 nm Amax: 0.005
Merck: 14,6032
BRN: 1730942
Exposure limits ACGIH: TWA 50 ppm
LogP: 1.06 at 20℃

Methyl tert-butyl ether is a liquid, colorless, volatile organic compound with a terpene-like odor, a vapor pressure of 249 mm Hg at 25° C, a water solubility of 51,000 mg/L, and a specific gravity of 0.74.
When released to the air, it has a 5 to 6 day half life and degrades primarily by reacting with photochemically produced hydroxyl radicals to form tertiary butyl formate.
The exposure to atmospheric UV light alone will not be sufficient to decompose this compound.

The low log Kow (1.24) suggests that Methyl tert-butyl ether will be very mobile in soils.
Methyl tert-butyl ether has a Henry's Constant of 0.022 and hence is not likely to form a vapor plume in the vadose zone above a dissolved phase plume.
Methyl tert-butyl ether is a gasoline additive.

Methyl tert-butyl ether undergoes oxidative degradation in the presence of propane-oxidizing bacterial strains.
The kinetic studies of heat-assisted persulfate oxidation of Methyl tert-butyl ether under various parameters suggests that the reaction follows the pseudo-first-order kinetics.
Methyl tert-butyl ether can be synthesized by acid catalyzed reaction between methanol and isobutene.

Methyl tert-butyl ether is an effective alternative to lead containing additives for enhancing the octane rating of gasoline.
A study suggests that the addition of Methyl tert-butyl ether increases the number of active sites during polymerization of propene by stopped-flow method.
Methyl tert-butyl ether may be used to synthesize fatty acid methyl esters (FAMEs) and glycerol tert-butyl ether via transesterification with canola oil under supercritical conditions.

Methyl tert-butyl ether (MTBE) is a flammable liquid that has been used as an additive for unleaded gasoline since the 1980s.
Methyl tert-butyl ether increases octane and oxygen levels in gasoline and reduces pollution emissions.
Because of concerns for groundwater contamination and water quality, Methyl tert-butyl ether is now banned or limited in several states.

Methyl tert-butyl ether's use as a gasoline additive was primarily as an oxygenate.
Oxygenates are compounds that contain oxygen and are added to gasoline to improve combustion and reduce emissions.
By promoting more complete combustion of fuel in the engine, oxygenates help reduce carbon monoxide (CO) and hydrocarbon emissions.

One of the significant environmental concerns associated with Methyl tert-butyl ether in gasoline was its potential to cause phase separation.
Methyl tert-butyl ether has a tendency to dissolve in water, and if gasoline containing MTBE comes into contact with water (such as in underground fuel storage tanks), it can mix with the water.
This leads to the formation of a separate Methyl tert-butyl ether-water layer at the bottom of the tank, creating a potential source of groundwater contamination.

In many regions, Methyl tert-butyl ether was gradually phased out and replaced with ethanol (ethyl alcohol) as an oxygenate in gasoline.
Ethanol is derived from renewable sources like corn or sugarcane, and its use as a fuel additive has gained popularity due to its lower environmental impact and potential to reduce greenhouse gas emissions compared to Methyl tert-butyl ether.

Methyl tert-butyl ether in Reformulated Gasoline (RFG): Reformulated gasoline, which is required in some areas to meet air quality standards, often included Methyl tert-butyl ether as one of the oxygenates to help reduce emissions.
However, concerns about its impact on the environment and water quality led to the transition away from Methyl tert-butyl ether in RFG formulations.

Methyl tert-butyl ether's use as a gasoline additive was not limited to a single country; it was employed worldwide in various gasoline blends.
The extent of its use, however, varied depending on regional regulations and environmental concerns.

Individuals working in industries where Methyl tert-butyl ether is used or produced may be at risk of occupational exposure.
Occupational health and safety guidelines are in place to protect workers from exposure to hazardous substances like Methyl tert-butyl ether.
Due to its flammable and volatile nature, Methyl tert-butyl ether requires careful handling and transportation to ensure safety.

Preparation
Methyl tert-butyl ether can be prepared by the reaction of potassium tert-butoxide and bromomethane.
Methyl tert-butyl ether also can be obtained by the acid-catalyzed addition of methanol to isobutene.

Suitable catalysts are solid acids such as bentonites, zeolites and – commonly used in industrial world scale MTBE-production units – macroporous acidic ion-exchange resins. The reaction is weakly exothermic with a heat of reaction of -37.7 kJ/mol.

Uses
Methyl tert-butyl ether (MTBE) was primarily used as a gasoline additive in unleaded gasoline in the United States prior to 2005, in the manufacture of isobutene, and as a chromatographic eluent especially in high pressure liquid chromatography.
It is also a pharmaceutical agent and can be injected into the gallbladder to dissolve gallstones (ATSDR, 1996).

Methyl tert-butyl ether is also used in the petrochemical industry.
By reversal of its formation reaction, MTBE can be cracked to isobutene and methanol on acidic catalysts at higher temperature than Methyl tert-butyl ether synthesis.
Methyl tert-butyl ether is used as a fuel component in fuel for gasoline engines.

Methyl tert-butyl ether is one of a group of chemicals commonly known as oxygenates because they raise the oxygen content of gasoline.
Methyl tert-butyl ether was commonly used as an oxygenate in gasoline to enhance its octane rating and improve combustion properties.
By raising the octane level, Methyl tert-butyl ether reduced engine knocking and allowed for higher engine compression ratios, resulting in improved engine performance.

As an oxygenate, Methyl tert-butyl ether helped gasoline burn more completely in engines, which led to reduced emissions of carbon monoxide (CO) and certain hydrocarbons, contributing to improved air quality in areas with high vehicular traffic.
Methyl tert-butyl ether was used in reformulated gasoline, required in some regions to meet air quality standards.

Apart from its use as a gasoline additive, Methyl tert-butyl ether found applications as a solvent in various industrial processes.
Methyl tert-butyl ether was used in the production of chemicals, pharmaceuticals, and other products.
Besides gasoline, Methyl tert-butyl ether was occasionally used as an octane booster in aviation and racing fuels.

Methyl tert-butyl ether is used in the following products: pharmaceuticals, perfumes and fragrances, laboratory chemicals, fuels and pH regulators and water treatment products.
Methyl tert-butyl ether has an industrial use resulting in manufacture of another substance (use of intermediates).
Methyl tert-butyl ether is used in the following areas: formulation of mixtures and/or re-packaging.

Methyl tert-butyl ether is used for the manufacture of: chemicals and rubber products.
Release to the environment of Methyl tert-butyl ether can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release, as processing aid and as processing aid.
Other release to the environment of Methyl tert-butyl ether is likely to occur from: indoor use as reactive substance.

Methyl tert-butyl ether was used as a blending component in gasoline to enhance its octane rating and improve its combustion characteristics.
The ability to increase octane levels without significantly altering other properties of gasoline made Methyl tert-butyl ether an attractive additive for gasoline manufacturers.

As an oxygenate additive in gasoline, Methyl tert-butyl ether helped to increase the oxygen content of the fuel.
The presence of oxygen in the fuel promotes more complete combustion, leading to reduced emissions of carbon monoxide and unburned hydrocarbons, which are harmful pollutants contributing to air pollution and smog formation.

Methyl tert-butyl ether's solubility in gasoline helped improve the stability of gasoline blends during storage.
It acted as a dispersant for certain components, preventing the separation of gasoline constituents over time.

Methyl tert-butyl ether found applications as a solvent in various industries.
It was used in the manufacturing of paints, coatings, adhesives, and other chemical products.
Its solvency properties made it valuable for dissolving and processing various compounds.

Methyl tert-butyl ether was utilized as an extraction solvent in certain chemical processes, especially in the production of butadiene and isobutylene from refinery streams.
In some areas, Methyl tert-butyl ether was used as a cleaner burning alternative to other gasoline additives like ethanol or methylcyclopentadienyl manganese tricarbonyl (MMT).
Methyl tert-butyl ether is also used in small amounts as a laboratory solvent and for some medical applications.

Hazard
Methyl tert-butyl ether slightly toxic by ingestion and inhalation.
Methyl tert-butyl ether, flammable when exposed to heat or flame.
Upper respiratory tract irritant and kidney damage.

Environmental Fate
Methyl tert-butyl ether can be released during manufacturing or blending with gasoline; during the storage, distribution, and transfer of Methyl tert-butyl ether-blended gasoline; and from spills or leaks or fugitive emissions at automotive service stations (U.S. EPA, 1994a).

Vapor emissions from Methyl tert-butyl ether-blended gasoline may also contribute to atmospheric levels (U.S. EPA, 1988).
Methyl tert-butyl ether is not expected to persist in the atmosphere because it undergoes destruction from reactions with hydroxyl radicals.

Synonyms
tert-Butyl methyl ether
Methyl tert-butyl ether
1634-04-4
MTBE
2-Methoxy-2-methylpropane
Methyl t-butyl ether
Propane, 2-methoxy-2-methyl-
T-BUTYL METHYL ETHER
Methyl-tert-butyl ether
Methyl-t-butyl ether
2-Methyl-2-methoxypropane
Methyl tertiary-butyl ether
tert-butylmethylether
Ether, tert-butyl methyl
Methyl 1,1-dimethylethyl ether
tert-Butylmethyl ether
tert-C4H9OCH3
1,1-dimethylethyl methyl ether
2-methoxy-2-methyl-propane
CCRIS 7596
CHEBI:27642
HSDB 5847
methyl-tert-butyl-ether
Methyl tert butyl ether
EINECS 216-653-1
UN2398
Methyl Tertiary Butyl Ether
BRN 1730942
tert-butyl-d9 methyl ether
UNII-29I4YB3S89
DTXSID3020833
29I4YB3S89
MFCD00008812
EC 216-653-1
tBME
4-01-00-01615 (Beilstein Handbook Reference)
tert-BuOMe
methyl-t-butylether
t-butylmethyl ether
methyltertbutyl ether
tertbutylmethyl ether
1219795-06-8
Methyl-tert-butylether
tert-Butyl methyl ether, for HPLC, >=99.8% (GC)
Driveron
MeOtBu
tBuOMe
t-butylmethylether
methylterbutyloxide
methyltertbutylether
tertbutylmethylether
methyl t-butylether
methylt-butyl ether
t-BuOMe
t-butyl methylether
t-butyl-methylether
tert-butylmethyether
MTBE ACS grade
tert.butylmethylether
methyl-t-butyl-ether
t-butyl methyi ether
t-butyl-methyl ether
t-butyl-methyl-ether
methyl tert-butylether
methyl tertbutyl ether
methyl-tert.butylether
methyl-tertbutyl ether
methyl-tertbutyl-ether
methyltert-butyl ether
tert -butylmethylether
tert butylmethyl ether
tert-butyl-methylether
tert. butylmethylether
tert.-butylmethylether
tert.butyl-methylether
tert.butylmethyl ether
tertbutyl methyl ether
tertbutyl(methyl)ether
Tert-butyl methylether
methy tert-butyl ether
methyl ter-butyl ether
metyl tert-butyl ether
ter-butyl methyl ether
tert-buty methyl ether
tert-buyl methyl ether
(tert-butyl)methylether
methyl tert.-butylether
methyl tert.butyl ether
methyl-tert butyl ether
methyl-tert. butylether
methyl-tert.-butylether
methyl-tert.butyl ether
MTBE-HP
tert-butyl-methyl ether
tert-butyl-methyl-ether
tert. butyl-methylether
tert.-butyl methylether
tert.-butyl-methylether
tert.-butylmethyl ether
tert.butyl methyl ether
Tert butyl methyl ether
TERT-BUTOXYMETHANE
methyl tert.-butyl ether
methyl-tert. butyl ether
tert. butyl-methyl-ether
tert.-butyl methyl ether
tert.-butyl-methyl ether
tert.-butyl-methyl-ether
methyl-tertiarybutyl ether
tert. Butyl methyl ether
tertiary butylmethyl ether
methyl tert.- butyl ether
Epitope ID:122671
tertiary-butyl methyl ether
Tertiary butyl methyl ether
(CH3)3COCH3
DTXCID30833
Propano, 2-metoxi-2-metil-
methyl tert-butyl ether (mtbe)
CHEMBL1452799
MTBE (Methyl tert-butyl ether)
(METHYL)(TERT-BUTYL)ETHER
AMY11032
tert-Butylmethyl ether, HPLC Grade
Methyl tertiary butyl ether (MTBE)
T-BUTYL METHYL ETHER [INCI]
Tox21_201184
LS-917
NA2398
tert-Butyl methyl ether, HPLC grade
METHYL TERT-BUTYL ETHER [MI]
AKOS000121105
METHYL TERT-BUTYL ETHER [IARC]
tert-Butyl methyl ether, LR, >=99%
UN 2398
TERT-BUTYLMETHYL ETHER [USP-RS]
NCGC00091717-01
NCGC00091717-02
NCGC00258736-01
tert-Butyl methyl ether, p.a., 99.5%
CAS-1634-04-4
Methyl Tertiary Butyl Ether - High Purity
tert-Butyl methyl ether, AR, >=99.5%
B0991
tert-Butyl methyl ether, analytical standard
tert-Butyl methyl ether, anhydrous, 99.8%
tert-Butyl methyl ether, PRA grade, >=99%
tert-Butyl methyl ether, reagent grade, 98%
tert-Butyl methyl ether, for HPLC, >=99.8%
tert-Butyl methyl ether, for HPLC, >=99.9%
tert-Butyl methyl ether, reagent grade, >=98%
Methyl-tert-butylether 100 microg/mL in Methanol
Q412346
tert-Butyl methyl ether, ACS reagent, >=99.0%
tert-Butylmethyl ether 100 microg/mL in Methanol
InChI=1/C5H12O/c1-5(2,3)6-4/h1-4H
J-509782
Methyl tert-butyl ether 2000 microg/mL in Methanol
Methyl tert-butyl ether [UN2398] [Flammable liquid]
tert-Butyl methyl ether, puriss. p.a., >=99% (GC)
Methyl tert-butyl ether [UN2398] [Flammable liquid]
MTBE ACS grade trace metal grade, stainless steel drum
tert-Butyl methyl ether, HPLC grade, for HPLC, 99.8%
tert-Butyl methyl ether, puriss. p.a., >=99.5% (GC)
tert-Butyl methyl ether, SAJ special grade, >=99.0%
Methyl tert-butyl ether (MTBE) 1000 microg/mL in Methanol
tert-Butyl Methyl Ether, Pharmaceutical Secondary Standard; Certified Reference Material
tert-Butyl methyl ether, United States Pharmacopeia (USP) Reference Standard
METHYL TRIBROMIDE
Methyl Tribromide is a brominated organic solvent, colorless liquid at room temperature, with a high refractive index, very high density, and sweet odor is similar to that of chloroform.
Methyl Tribromide is widely used as a solvent for waxes, oils and greases.
Miscible with Methyl Tribromide, benzene, ethanol, petroleum ether, acetone, diethyl ether and oils.

CAS Number: 75-25-2
EC Number: 200-854-6
Molar Mass: 252.75 g/mol
Chemical Formula: CHBr3

Methyl Tribromide is a brominated organic solvent, colorless liquid at room temperature, with a high refractive index, very high density, and sweet odor is similar to that of chloroform.
Methyl Tribromide is one of the four haloforms, the others being fluoroform, chloroform, and iodoform.

Methyl Tribromide can be prepared by the haloform reaction using acetone and sodium hypobromite, by the electrolysis of potassium bromide in ethanol, or by treating chloroform with aluminium bromide.
Currently Methyl Tribromide main use is as a laboratory reagent.

Methyl Tribromide is widely used as a solvent for waxes, oils and greases.
Methyl Tribromide is utilized for mineral ore separation in geological tests.

Methyl Tribromide is used as an intermediate in chemical synthesis as well as a laboratory reagent.
Methyl Tribromide is the ingredient of fire-resistant chemicals and fluid gauges.
Methyl Tribromide acts as a sedative and as cough reducing agent.

Methyl Tribromide is a brominated organic solvent with the formula CHBr3.
Methyl Tribromide has an odor similar to chloroform and Methyl Tribromide density is very high (2,89).
Miscible with chloroform, benzene, ethanol, petroleum ether, acetone, diethyl ether and oils.

Methyl Tribromide is classified as a member of the Trihalomethanes.
Trihalomethanes are organic compounds in which exactly three of the four hydrogen atoms of methane (CH4) are replaced by halogen atoms.
Trace amounts of 1,2-dibromoethane occur naturally in the ocean, where Methyl Tribromide is formed probably by algae and kelp.

Methyl Tribromide is formally rated as an unfounded non-carcinogenic (IARC 3) potentially toxic compound.
Exposure to Methyl Tribromide may occur from the consumption of chlorinated drinking water.

The acute (short-term) effects from inhalation or ingestion of high levels of Methyl Tribromide in humans and animals consist of nervous system effects such as the slowing down of brain functions, and injury to the liver and kidney.
Chronic (long-term) animal studies indicate effects on the liver, kidney, and central nervous system (CNS) from oral exposure to Methyl Tribromide.

Human data are considered inadequate in providing evidence of cancer by exposure to Methyl Tribromide, while animal data indicate that long-term oral exposure can cause liver and intestinal tumors.
Methyl Tribromide has been classified as a Group B2, probable human carcinogen.
Most of the Methyl Tribromide that enters the environment is formed as disinfection byproducts known as the trihalomethanes when chlorine is added to drinking water or swimming pools to kill bacteria.

In the past, Methyl Tribromide was used as a solvent, sedative and flame retardant, but now Methyl Tribromide is mainly used as a laboratory reagent.
Bromine is a halogen element with the symbol Br and atomic number 35.

Diatomic bromine does not occur naturally, but bromine salts can be found in crustal rock.
Methyl Tribromide is a pale yellow liquid at room temperature, with a high refractive index, very high density, and sweet odor is similar to that of chloroform.

Methyl Tribromide (CHBr3) is a brominated organic solvent, pale yellow liquid at room temperature, with a high refractive index, very highdensity, and sweet odor is similar to that of.
Methyl Tribromide is a trihalomethane, and is one of the four haloforms, the others beingfluoroform, and iodoform.

Methyl Tribromide can be prepared by the haloform reaction using acetone and sodium hypobromite, by the electrolysis of potassium bromide in ethanol, or by treating with aluminum bromide.
Currently Methyl Tribromide main use is as a laboratory reagent.

Methyl Tribromide is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.
Methyl Tribromide is used in formulation or re-packing, at industrial sites and in manufacturing.

Methyl Tribromide (CHBr3) is a pale yellowish liquid with a sweet odor similar to chloroform, a halomethane or haloform.
Methyl Tribromide refractive index is 1.595 (20 °C, D).

Small amounts are formed naturally by plants in the ocean.
Methyl Tribromide is somewhat soluble in water and readily evaporates into the air.
Most of the Methyl Tribromide that enters the environment is formed as byproducts when chlorine is added to drinking water to kill bacteria.

Methyl Tribromide is one of the trihalomethanes closely related with fluoroform, chloroform and iodoform.
Methyl Tribromide is soluble in about 800 parts water and is miscible with alcohol, benzene, chloroform, ether, petroleum ether, acetone, and oils.
Methyl Tribromide LD50 is 7.2 mmol/kg in mice, or 1.8g/kg.

Methyl Tribromide can be prepared by the haloform reaction using acetone and sodium hypobromite or by the electrolysis of alcoholic solution of potassium or sodium bromide.

Methyl Tribromide is used as a solvent and to make pharmaceuticals.
Often stabilized with 1 to 3% ethanol.

Applications of Methyl Tribromide:
Methyl Tribromide is widely used as a solvent for waxes, oils and greases.
Methyl Tribromide is utilized for mineral ore separation in geological tests.

Methyl Tribromide is used as an intermediate in chemical synthesis as well as a laboratory reagent.
Methyl Tribromide is the ingredient of fire-resistant chemicals and fluid gauges.
Methyl Tribromide acts as a sedative and as cough reducing agent.

Uses of Methyl Tribromide:
As a fluid for mineral ore separation; as a laboratory reagent; in the electronics industry for quality assurance programs; formerly as a sedative and antitussive

Methyl Tribromide is a colorless to yellow liquid with a density about three times that of water.
Methyl Tribromide has an odor and sweetish taste similar to chloroform and is not combustible.

Methyl Tribromide has been used as a degreasing solvent, in chemical synthesis, and in fire extinguishers, and is no longer used as a sedative for children with whooping cough.
Currently, Methyl Tribromide is produced only in small amounts for use in laboratories and in geological and electronics testing.

In separating mixtures of minerals.
Methyl Tribromide is used as a fluid for mineral ore separation in geological tests, as a laboratory reagent, and in the electronics industry in quality assurance programs.

Methyl Tribromide was formerly used as a solvent for waxes, greases, and oils, as an ingredient in fire-resistant chemicals and in fluid gauges.
Methyl Tribromide was also used in the early part of this century as a medicine to help children with whooping cough get to sleep.
Currently, Methyl Tribromide is only produced in small amounts for use in laboratories and in geological and electronics testing.

Methyl Tribromide is used as a fluid for mineral ore separation in geological tests, as a laboratory reagent, and in the electronics industry in quality assurance programs.
Methyl Tribromide was formerly used as a solvent for waxes, greases, and oils, as an ingredient in fire-resistant chemicals and in fluid gauges.
Methyl Tribromide has also been used as an intermediate in chemical synthesis, as a sedative, and as a cough suppression agent.

Only small quantities of Methyl Tribromide are currently produced industrially in the United States.
In the past, Methyl Tribromide was used as a solvent, and flame retardant, but now Methyl Tribromide is mainly used as a laboratory reagent, for example as an extraction solvent.

Methyl Tribromide's high density makes Methyl Tribromide useful for separation of minerals by density.
When two samples are mixed with Methyl Tribromide and then allowed to settle, the top layer will contain minerals lighter than Methyl Tribromide, and the bottom layer will contain heavier minerals.
Slightly less dense minerals can be separated in the same way by mixing the Methyl Tribromide with a small amount of a less dense and fully miscible solvent.

Methyl Tribromide is used as a fluid for mineral ore separation in geological tests, as a laboratory reagent, and in the electronics industry in quality assurance programs.
Methyl Tribromide has also been used as an intermediate in chemical synthesis, as a sedative, and as a cough suppression agent.

Only small quantities of Methyl Tribromide are currently produced industrially in the United States.
In the past, Methyl Tribromide was used as a solvent, sedative and flame retardant, but now Methyl Tribromide is mainly used as a laboratory reagent, for example as an extraction solvent.

Methyl Tribromide also has medical uses; injections of Methyl Tribromide are sometimes used instead of epinephrine to treat severe asthma cases.

Methyl Tribromide's high density makes Methyl Tribromide useful for separation of minerals by density.
When two samples are mixed with Methyl Tribromide and then allowed to settle, the top layer will contain minerals less dense than Methyl Tribromide, and the bottom layer will contain denser minerals.
Slightly less dense minerals can be separated in the same way by mixing the Methyl Tribromide with a small amount of a less dense and miscible solvent.

Methyl Tribromide is known as an inhibitor of methanogenesis and is a common component of seaweed.
Following research by CSIRO and Methyl Tribromide spin-off FutureFeed, several companies are now growing seaweed, in particular from the genus Asparagopsis, to use as a feed additive for livestock to reduce methane emissions from ruminants.

Methyl Tribromide is used as a intermediate for pharmaceuticals and other organic compounds.
Methyl Tribromide is also used as a solvent for waxes and oils.

Methyl Tribromide is used for synth of pharmaceuticals; used in shipbuilding, aircraft, and aerospace industries; used in fire extinguishers.
Methyl Tribromide is used as a heavy liquid floatation agent in mineral separation, sedimentary petrographical surveys, and purification of materials such as quartz.

Methyl Tribromide is used as an industrial solvent in liquid-solvent extractions, in nuclear magnetic resonance studies.
Methyl Tribromide is used as a catalyst, initiator, or sensitizer in polymer reactions, and in vulcanization of rubber.

Use Classification of Methyl Tribromide:
Hazardous Air Pollutants (HAPs)

Health Hazards - Carcinogens

Therapeutic Uses of Methyl Tribromide:
Methyl Tribromide was formerly used as an antiseptic and sedative.

Typical Properties of Methyl Tribromide:

Chemical Properties:
Methyl Tribromide is a colorless to pale yellow liquid with a high refractive index, very high density, and sweetish odor is similar to that of chloroform.
Methyl Tribromide is slightly soluble in water and is nonflammable.
Methyl Tribromide can form in drinking water as a by-product from the reaction of chlorine with dissolved organic matter and bromide ions.

Physical properties:
Clear, colorless to yellow liquid with a chloroform-like odor.
Odor threshold concentration in water is 0.3 mg/kg

Methyl Tribromide is a colorless to pale yellow liquid with a sweetish odor.
The chemical formula for Methyl Tribromide is CBr3H and the molecular weight is 252.75 g/mol.

The vapor pressure for Methyl Tribromide is 5 mm Hg at 20 °C, and Methyl Tribromide has an octanol/water partition coefficient(log Kow) of 2.38.
Methyl Tribromide has an odor threshold of 1.3 parts per million (ppm).

Methyl Tribromide is slightly soluble in water and is nonflammable.
Methyl Tribromide can form in drinking water as a by-product from the reaction of chlorine with dissolved organic matter and bromide ions.

Manufacturing Methods of Methyl Tribromide:
Prepared from acetone and sodium hypobromite.

By heating acetone or ethanol with bromine and alkali hyroxide and recovery of distillation (similar to acetone process of chloroform).

Analytic Laboratory Methods of Methyl Tribromide:
To support studies exploring the relation between exposure to trihalomethanes (THMs) and health effects, we have developed an automated analytical method using headspace solid-phase microextraction coupled with capillary gas chromatography and mass spectrometry.

This method quantitates trace levels of THMs (chloroform, bromodichloromethane, dibromochloromethane, and Methyl Tribromide) and methyl tertiary-butyl ether in tap water.
Detection limits of less than 100 ng/L for all analytes and linear ranges of three orders of magnitude are adequate for measuring the THMs in tap water samples tested from across the United States.

Method: NIOSH 1003, Issue 3
Procedure: gas chromatography with flame ionization detection
Analyte: Methyl Tribromide
Matrix: air
Detection Limit: 6.0 ug/sample.

Method: ASTM D5790
Procedure: gas chromatography/mass spectrometry
Analyte: Methyl Tribromide
Matrix: treated drinking water, wastewater, and ground water
Detection Limit: 0.2 ug/L.

Method: EPA-EAD 601
Procedure: gas chromatography with electrolytic conductivity or microcoulometric detector
Analyte: Methyl Tribromide
Matrix: municipal and industrial discharges
Detection Limit: 0.2 ug/L.

Clinical Laboratory Methods of Methyl Tribromide:
To support studies exploring the relation between exposure to trihalomethanes (THMs) and adverse health effects, an automated analytical method was developed using capillary gas chromatography (GC) and high-resolution mass spectrometry (MS) with selected ion mass detection and isotope-dilution techniques.
This method quantified trace levels of THMs (including chloroform, bromodichloromethane, dibromochloromethane, and Methyl Tribromide) and methyl tert-butyl ether (MTBE) in human blood.

Analyte responses were adequate for measuring background levels after extraction of these volatile organic compounds with either purge-and-trap extraction or headspace solid-phase microextraction (SPME).
The SPME method was chosen because of Methyl Tribromide ease of use and higher throughput.

Detection limits for the SPME GC-MS method ranged from 0.3 to 2.4 ng/L, with linear ranges of three orders of magnitude.
This method proved adequate for measuring the THMs and MTBE in most blood samples tested from a diverse U.S. reference population.

Purification Methods of Methyl Tribromide:
The storage and stability of Methyl Tribromide and chloroform are similar.
Ethanol, added as a stabilizer, is removed by washing with H2O or with saturated CaCl2 solution, and the CHBr3, after drying with CaCl2 or K2CO3, is fractionally distilled.

Prior to distillation, CHBr3 has also been washed with conc H2SO4 until the acid layer is no longer coloured, then dilute NaOH or NaHCO3, and H2O.
A further purification step is fractional crystallisation by partial freezing.

Structure of Methyl Tribromide:
The molecule adopts tetrahedral molecular geometry with C3v symmetry.

MeSH Pharmacological Classification of Methyl Tribromide:

Carcinogens:
Substances that increase the risk of NEOPLASMS in humans or animals.
Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.

Teratogens:
An agent that causes the production of physical defects in the developing embryo.

Environment and Toxicology of Methyl Tribromide:
Natural production of Methyl Tribromide by phytoplankton and seaweeds in the ocean is thought to be Methyl Tribromide predominant source in the environment.

However, locally significant amounts of Methyl Tribromide enter the environment formed as disinfection byproducts known as trihalomethanes when chlorine is added to drinking water to kill bacteria.
Methyl Tribromide is somewhat soluble in water and readily evaporates into the air.

Methyl Tribromide is the main trihalomethane produced in beachfront salt water swimming pools with concentrations as high as 1.2 ppm (parts per million).
Concentrations in freshwater pools are 1000 times lower.
Occupational skin exposure limits are set at 0.5 ppm.

Methyl Tribromide may be hazardous to the environment, and special attention should be given to aquatic organisms.
Methyl Tribromide volatility and environmental persistence makes Methyl Tribromide's release, either as liquid or vapor, strongly inadvisable.

Methyl Tribromide can be absorbed into the body by inhalation and through the skin.
Methyl Tribromide is irritating to the respiratory tract, the eyes, and the skin, and may cause effects on the central nervous system and liver, resulting in impaired functions.

Methyl Tribromide is soluble in about 800 parts water and is miscible with alcohol, benzene, chloroform, ether, petroleum ether, acetone, and oils.
Methyl Tribromide LD50 is 7.2 mmol/kg in mice, or 1.8g/kg.

The International Agency for Research on Cancer (IARC) concluded that Methyl Tribromide is not classifiable as to human carcinogenicity.
The EPA classified Methyl Tribromide as a probable human carcinogen.

Safe Storage of Methyl Tribromide:
Separated from strong bases, oxidants, metals and food and feedstuffs.
Keep in the dark.
Ventilation along the floor.

Store only if stabilized.
Store in an area without drain or sewer access.
Provision to contain effluent from fire extinguishing.

Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Reactivity Profile of Methyl Tribromide:
Heating Methyl Tribromide to decomposition produces highly toxic fumes of carbon oxybromide (carbonyl bromide) and hydrogen bromide.
Reaction with powdered potassium or sodium hydroxide, Li or Na/K alloys, is violently exothermic.
Explosive reaction with crown ethers in the presence of potassium hydroxide.

Safety Profile of Methyl Tribromide:
Suspected carcinogen with experimental neoplastigenic data.
A human poison by ingestion.

Moderately toxic by intraperitoneal and subcutaneous routes.
Human mutation data reported.

Methyl Tribromide can damage the liver to a serious degree and cause death.
Methyl Tribromide has anesthetic properties simdar to those of chloroform, but is not sufficiently volatile for inhalation purposes and is far too toxic for human use.
As a sedative and antitussive Methyl Tribromide medicinal application has resulted in numerous poisonings.

Inhalation of small amounts causes irritation, provoking the flow of tears and saliva, and reddening of the face.
Abuse can lead to adhction and serious consequences.
Explosive reaction with crown ethers or potassium hydroxide.

Violent reaction with acetone or bases.
Incompatible with Li or NaK alloys.
When heated to decomposition Methyl Tribromide emits hghly toxic fumes of Br-.

First Aid of Methyl Tribromide:

EYES:
First check the victim for contact lenses and remove if present.
Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center.

Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN:
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing.
Gently wash all affected skin areas thoroughly with soap and water.

IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop.
IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.

INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop.

Provide proper respiratory protection to rescuers entering an unknown atmosphere.
Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION:
DO NOT INDUCE VOMITING.
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center.

Be prepared to transport the victim to a hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body.

DO NOT INDUCE VOMITING.
IMMEDIATELY transport the victim to a hospital.

OTHER:
Since this chemical is a known or suspected carcinogen you should contact a physician for advice regarding the possible long term health effects and potential recommendation for medical monitoring.
Recommendations from the physician will depend upon the specific compound, Methyl Tribromide chemical, physical and toxicity properties, the exposure level, length of exposure, and the route of exposure.

Fire Fighting of Methyl Tribromide:

SMALL FIRE:
Dry chemical, CO2, water spray or regular foam.

LARGE FIRE:
Water spray, fog or regular foam.
Move containers from fire area if you can do Methyl Tribromide without risk.
Dike fire-control water for later disposal; do not scatter Methyl Tribromide.

FIRE INVOLVING TANKS OR CAR/TRAILER LOADS:
Fight fire from maximum distance or use unmanned hose holders or monitor nozzles.
Do not get water inside containers.

Cool containers with flooding quantities of water until well after fire is out.
Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.

ALWAYS stay away from tanks engulfed in fire.
For massive fire, use unmanned hose holders or monitor nozzles; if this is impossible, withdraw from area and let fire burn.

Fire Fighting Procedures of Methyl Tribromide:

Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.

If material on fire or involved in fire:
Do not extinguish fire unless flow can be stopped.
Extinguish fire using agent suitable for type of surrounding fire (Material itself does not burn or burns with difficulty.)

Use water in flooding quantities as fog.
Cool all affected containers with flooding quantities of water.

Apply water from as far a distance as possible.
Use foam, dry chemical, or carbon dioxide.
Keep run-off water out of sewers and water sources.

Isolation and Evacuation of Methyl Tribromide:
As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL:
Increase, in the downwind direction, as necessary, the isolation distance shown above.

FIRE:
If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions.
Also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Spillage Disposal of Methyl Tribromide:

Personal protection:
Complete protective clothing including self-contained breathing apparatus.
Do NOT let this chemical enter the environment.

Collect leaking liquid in sealable containers.
Absorb remaining liquid in sand or inert absorbent.

Then store and dispose of according to local regulations.
Do NOT wash away into sewer.

Personal precautions, protective equipment and emergency procedures:
Wear respiratory protection.
Avoid breathing vapors, mist or gas.

Ensure adequate ventilation.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Disposal Methods of Methyl Tribromide:
Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number U225, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.

Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations.
Concentrations shall be lower than applicable environmental discharge or disposal criteria.

Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur.
Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal.

If Methyl Tribromide is not practicable to manage the chemical in this fashion, Methyl Tribromide must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.
Offer surplus and non-recyclable solutions to a licensed disposal company.

Contact a licensed professional waste disposal service to dispose of Methyl Tribromide.
Dissolve or mix Methyl Tribromide with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber; Contaminated packaging: Dispose of as unused product.

A potential candidate for rotary kiln incineration at a temperature range of 820 to 1,600 °C and residence times of seconds for liquids and gases, and hours for solids.
A potential candidate for liquid injection incineration at a temperature range of 650 to 1,600 °C and a residence time of 0.1 to 2 seconds.

A potential candidate for fluidized bed incineration at a temperature range of 450 to 980 °C and residence times of seconds for liquids and gases, and longer for solids.
If packaged as an aerosol, be careful when releasing in an incinerator or Methyl Tribromide will blow past the combustion zone.

Preventive Measures of Methyl Tribromide:

Personal precautions, protective equipment and emergency procedures:
Wear respiratory protection.
Avoid breathing vapors, mist or gas.

Ensure adequate ventilation.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Precautions for safe handling:
Avoid contact with skin and eyes.
Avoid inhalation of vapor or mist.

Avoid contact with skin, eyes and clothing.
Wash hands before breaks and immediately after handling Methyl Tribromide.

Gloves must be inspected prior to use.
Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with Methyl Tribromide.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.

Nonfire Spill Response of Methyl Tribromide:
Do not touch or walk through spilled material.

Stop leak if you can do Methyl Tribromide without risk.
Fully encapsulating, vapor-protective clothing should be worn for spills and leaks with no fire.

SMALL SPILL:
Pick up with sand or other non-combustible absorbent material and place into containers for later disposal.

LARGE SPILL:
Dike far ahead of liquid spill for later disposal.
Prevent entry into waterways, sewers, basements or confined areas.

Identifiers of Methyl Tribromide:
CAS number: 75-25-2
EC index number: 602-007-00-X
EC number: 200-854-6
Hill Formula: CHBr₃
Molar Mass: 252.75 g/mol
HS Code: 2903 69 19
Quality Level: MQ200

Boiling point: 149.5 °C (1013 mbar)
Density: 2.89 g/cm3 (20 °C)
Flash point: 30 °C does not flash
Melting Point: 8.0 °C
Vapor pressure: 7.5 hPa (25 °C)
Solubility: 3.2 g/l

CAS Number: 75-25-2
Abbreviations: R-20B3
UN: 2515
Beilstein Reference: 1731048
ChEBI: CHEBI:38682
ChEMBL: ChEMBL345248
ChemSpider: 13838404
DrugBank: DB03054
ECHA InfoCard: 100.000.777
EC Number: 200-854-6
Gmelin Reference: 49500
KEGG: C14707
MeSH: Methyl Tribromide
PubChem CID: 5558
RTECS number: PB5600000
UNII: TUT9J99IMU
UN number: 2515
CompTox Dashboard (EPA): DTXSID1021374
InChI: InChI=1S/CHBr3/c2-1(3)4/h1H
Key: DIKBFYAXUHHXCS-UHFFFAOYSA-N
SMILES: BrC(Br)Br

Properties of Methyl Tribromide:
Chemical formula: CHBr3
Molar mass: 252.731 g·mol−1
Appearance: Colorless liquid
Density: 2.89 g mL−1
Melting point: −4 to 16 °C; 25 to 61 °F; 269 to 289 K
Boiling point: 147 to 151 °C; 296 to 304 °F; 420 to 424 K
Solubility in water: 3.2 g L−1 (at 30 °C)
log P: 2.435
Vapor pressure: 670 Pa (at 20.0 °C)
Henry's law constant (kH): 17 μmol Pa−1 kg−1
Acidity (pKa): 13.7
Magnetic susceptibility (χ): -82.60·10−6 cm3/mol
Refractive index (nD): 1.595

Molecular Weight: 252.73
XLogP3-AA: 2.8
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 0
Rotatable Bond Count: 0
Exact Mass: 251.76079
Monoisotopic Mass: 249.76284
Topological Polar Surface Area: 0 Ų
Heavy Atom Count : 4
Complexity: 8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Methyl Tribromide:
Assay (GC, area %) : ≥ 98.0 %
Identity (IR-spectrum): passes test
Density: 2.81
Melting Point: 8°C to 9°C
Boiling Point: 148°C to 150°C
Flash Point: None
UN Number: UN2515
Beilstein: 1731048
Merck Index: 14,1420
Refractive Index: 1.585
Quantity: 250g
Solubility Information: Slightly soluble in water.
Sensitivity: Light sensitive
Formula Weight: 252.73
Percent Purity: 97%
Chemical Name or Material: Methyl Tribromide, Stabilized with ethanol

Thermochemistry of Methyl Tribromide:
Heat capacity (C): 130.5 J K−1 mol−1
Std enthalpy of formation (ΔfH⦵298): 6.1–12.7 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): −549.1–−542.5 kJ mol−1

Related compounds of Methyl Tribromide:

Related alkanes:
Dibromomethane
Tetrabromomethane
1,1-Dibromoethane
1,2-Dibromoethane
Tetrabromoethane

Names of Methyl Tribromide:

Preferred IUPAC name:
Tribromomethane

Other names:
Bromoform
Methenyl tribromide
Methyl tribromide
Tribromomethane

Synonyms of Methyl Tribromide:
Tribromomethane
Methane tribromide
Methyl tribromide
Bromoform
tribromomethane
75-25-2
Methane, tribromo-
Tribrommethan
Methenyl tribromide
Methyl tribromide
Tribrommethaan
Tribromometan
Bromoforme
Bromoformio
CHBr3
RCRA waste number U225
NCI-C55130
UNII-TUT9J99IMU
NSC 8019
TUT9J99IMU
CHEBI:38682
MFCD00000128
Bromoforme
Bromoformio
Tribrommethaan
Tribrommethan
Tribromometan
CCRIS 98
Bromoform
MBR
HSDB 2517
EINECS 200-854-6
UN2515
RCRA waste no. U225
BRN 1731048
bromo form
AI3-28587
Tri bromo methane
WLN: EYEE
Bromoform, technical grade
DSSTox_CID_1374
DSSTox_RID_76118
DSSTox_GSID_21374
SCHEMBL18691
4-01-00-00082
BIDD:ER0622
Bromoform, puriss., 97.0%
CHEMBL345248
DTXSID1021374
NSC8019
Bromoform
AMY21869
BCP10566
Bromoform (stabilized with Ethanol)
NSC-8019
ZINC8101061
Tox21_200189
Bromoform 100 microg/mL in Methanol
Bromoform, 96%, stab. with ethanol
AKOS009031540
AT27291
Bromoform 5000 microg/mL in Methanol
DB03054
UN 2515
CAS-75-25-2
Bromoform, puriss., >=99.0% (GC)
NCGC00091318-01
NCGC00091318-02
NCGC00257743-01
BP-21414
I606
Tribromomethane (stabilized with Ethanol)
Tribromomethane 100 microg/mL in Methanol
B0806
FT-0623248
FT-0623471
S0653
T0348
Bromoform, amylene stabilized, analytical standard
Q409799
J-519947
Bromoform, contains 1-3% ethanol as stabilizer, 96%
F0001-1896
Bromoform - contains 60-120ppm 2-Methyl-2-butene as stabilizer
BROMOFORM (CONTAINS 60-120PPM 2-METHYL-2-BUTENE AS STABILIZER)
Bromoform, contains 60-120 ppm 2-methyl-2-butene as stabilizer, 99%
220-823-0
2909-52-6
Bromform
Bromoform
Bromoforme
Bromoformi
Bromoformio
Bromofórmio
Bromoformo
CHBr3
Methane, tribromo-
methyl tribromide
MFCD00000128
Tribrommethaan
Tribrommethan
tribromometano
tribromometano
tribromomethane
Tribromométhane
[75-25-2]
200-854-6MFCD00000128
4471-18-5
Bromoform - contains 60-120ppm 2-Methyl-2-butene as stabilizer
Bromoform|Tribromomethane
Bromoform-d
Bromoforme
Bromoforme
Bromoformio
Bromoformio
MBR
METHENYL TRIBROMIDE
Tri bromo methane
Tribrommethaan
Tribrommethaan
Tribrommethan
Tribrommethan
tribromo methane
Tribromometan
Tribromometan
Tribromomethane, Methane tribromide, Methyl tribromide
TRIBROMOMETHANE|TRIBROMOMETHANE
WLN: EYEE

MeSH of Methyl Tribromide:
bromoform
tribromomethane
Methylal
3(2H)-Isothiazolone, 5-chloro-2-methyl-, 4-Isothiazolin-3-one, 5-chloro-2-methyl-, 5-Chloro-2-methyl-3(2H)-isothiazolone, 5-Chloro-2-methylisothiazol-3-one, CMIT, Kathon CG 5243, MethylchloroisothiazolinoneMETHYLCHLOROISOTHIAZOLINONE, N° CAS : 26172-55-4 - Methylchloroisothiazolinone. Origine(s) : Synthétique. Autres langues : Methylchlorisothiazolinon, Metilcloroisotiazolinona. Nom INCI : METHYLCHLOROISOTHIAZOLINONE. Nom chimique : 5-Chloro-2-methyl-2H-isothiazol-3-one. N° EINECS/ELINCS : 247-500-7, Classification : Règlementé, Conservateur, La Méthylchloroisothiazolinone plus connue sous l'acronyme de CMIT, est un conservateur utilisé dans les produits cosmétiques et ménagers conjointement avec de la Methylisothiazolinone (MIT). La CMIT ne peut pas être utilisée seule, mais uniquement avec de la MIT. De fait comme la MIT est interdite dans les produits non rincés, la Dans les cosmétiques : Utilisable uniquement avec de la Methylisothiazolinone dans les produits rincés dans les conditions suivantes : 0,0015 % (d'un mélange dans un rapport 3:1 de 5-chloro-2-méthyl-isothiazol-3(2H)-one et de 2-méthylisothiazol-3(2H)-one) Ses fonctions (INCI): Conservateur : Inhibe le développement des micro-organismes dans les produits cosmétiques.Noms français : 3(2H)-ISOTHIAZOLONE, 5-CHLORO-2-METHYL; 4-ISOTHIAZOLIN-3-ONE, 5-CHLORO-2-METHYL-; Chloro-5 méthyl-2 isothiazolin-4 one-3; Chloromethylisothiazolinone; Methylchloroisothiazolinone. Noms anglais : 5-chloro-2-methyl-4-isothiazolin-3-one. Utilisation et sources d'émission: Fabrication de pesticides. 247-500-7 [EINECS] 26172-55-4 [RN] 3(2H)-Isothiazolone, 5-chloro-2-methyl- [ACD/Index Name] 5-Chlor-2-methyl-1,2-thiazol-3(2H)-on [German] [ACD/IUPAC Name] 5-Chloro-2-methyl-1,2-thiazol-3(2H)-one [ACD/IUPAC Name] 5-Chloro-2-méthyl-1,2-thiazol-3(2H)-one [French] [ACD/IUPAC Name] 5-Chloro-2-methyl-4-isothiazolin-3-one 5-Chloro-2-methyl-4-isothiazolin-3-one (CMI) 5-chloro-2-methylisothiazol-3(2h)-one chloromethylisothiazolinone DEL7T5QRPN Methylchloroisothiazolinone [Wiki] MFCD00792550 [MDL number] 1210149 2,3-dihydro-2-methyl-3-oxo-5-chloroisothiazole 2682-20-4 MIT 2-methyl-5-chloro-3-isothiazolone 2-METHYL-5-CHLORO-4-ISOTHIAZOLIN-3-ONE 2-methyl-5-chloroisothiazolin-3-one 4-Isothiazolin-3-one, 5-chloro-2-methyl- 55965-84-9 CMIT, MIT 5-Chloride-2-Methyl-4-Isothiazoline-3-Ketone 5-chloro-2-methyl-1,2-thiazol-3-one 5-chloro-2-methyl-2,3-dihydro-1,2-thiazol-3-one 5-CHLORO-2-METHYL-2H-ISOTHIAZOL-3-ONE 5-Chloro-2-methyl-3(2H)-isothiazolone 5-Chloro-2-methyl-3-isothiazolone 5-chloro-2-methyl-4- isothiazolin-3-one 5-Chloro-2-methyl-4-isothiazol-3-one 5-chloro-2-methyl-4-isothiazolin-3-one (active ingredient >14%, cmi/mi 2.5 - 4.0) 5-chloro-2-methyl-4-isothiazolin-3-one(cmi) 5-chloro-2-methyl-4-isothiazolin-3-one(cmit) 5-chloro-2-methyl-4-isothiazoline-3-one 5-Chloro-2-methyl-isothiazol-3-one 5-chloro-N-methylisothiazolone CMIT EINECS 247-500-7 isothiazolin-3-one, 5-chloro-2-methyl- Kathon CG 5243 Kathon IXE MCI MFCD04041015 Plant preservative mixture|PPM
METHYLAL
Methylal is a colorless liquid with a low boiling point, low viscosity and excellent dissolving power.
Methylal is the dimethyl acetal of formaldehyde.


CAS Number: 109-87-5
EC Number: 203-714-2
MDLNumber: MFCD00008495
Molecular Formula: C3H8O2 / CH2-(OCH3)2
Chemical formula: C3H8O2



SYNONYMS:
Methane, dimethoxy-, Dimethyl formal, Anesthenyl, Dimethoxymethane, Formal, Formaldehyde dimethyl acetal, Methoxymethyl methyl ether, Methylene dimethyl ether, Methylene glycol dimethylether, (CH3O)2CH2, Methylenedioxydimethane, Metylal, UN 1234, Formaldehyde methyl ketal, 2,4-Dioxapentane, Dimethylacetal formaldehyde, Bis(methoxy)methane, dimethoxymethane, formaldehyde dimethylacetal, methoxymethyl methyl ether, methylene dimethyl ether, 2,4-Dioxapentane, Anesthenyl, Bis(methoxy)methane, Dimethoxymethane, Dimethyl formal, Formal, Formaldehyde dimethyl acetal, Formaldehyde, methyl ketal, Methoxymethyl methylether, Methylal, Methylene dimethyl ether, 2,4-Dioxapentane, Anesthenyl, Bis(methoxy)methane, Dimethoxymethane, Dimethyl formal, Formal, Formaldehyde dimethyl acetal, Formaldehyde dimethylacetal, Formaldehyde methyl ketal, Methane, dimethoxy-, Methoxymethyl methyl ether, Methylene dimethyl ether, Metylal [Polish], [ChemIDplus] UN1234, Dimethoxymethane, Formal, Formaldehyde Dimethylacetal, Methoxymethyl Methyl Ether, Methylene Dimethyl Ether, Methane, dimethoxy-, Dimethyl formal, Anesthenyl, Dimethoxymethane, Formal, Formaldehyde dimethyl acetal, Methoxymethyl methyl ether, Methylene dimethyl ether, Methylene glycol dimethylether, (CH3O)2CH2, Methylenedioxydimethane, Metylal, UN 1234, Formaldehyde methyl ketal, 2,4-Dioxapentane, Dimethylacetal formaldehyde, Bis(methoxy)methane, Dimethoxymethane, METHYLAL, 109-87-5,Formal, Methane, dimethoxy-, Formaldehyde dimethyl acetal, Dimethyl formal, Anesthenyl, 2,4-Dioxapentane, Methylene dimethyl ether, Bis(methoxy)methane, Methoxymethyl methyl ether, Metylal, Formaldehyde methyl ketal,
Formaldehyde dimethylacetal, bis(methyloxy)methane, Methylene glycol dimethylether, 7H1M4G2NUE, CHEBI:48341, Dimethoxy methane, MFCD00008495, HSDB 1820,
EINECS 203-714-2, UN1234, UNII-7H1M4G2NUE, Dimethylformal, AI3-16096, CCRIS 9397, Methylene Glycol Dimethyl Ether, Dimethoxy-Methane, Methylenedioxydimethane, METHYLAL [HSDB], METHYLAL [INCI], METHYLAL [MI], Dimethoxymethane 99.5%, Dimethylacetal formaldehyde, METHYLAL [WHO-DD], EC 203-714-2, CHEMBL15537, (CH3O)2CH2, DTXSID1025564, AKOS000120977, UN 1234, Dimethoxymethane, ReagentPlus(R), 99%, Methylal [UN1234], D0637, FT-0625028, NS00003248, Formaldehyde dimethyl acetal, analytical standard, Q411496, J-520340, InChI=1/C3H8O2/c1-4-3-5-2/h3H2,1-2H, F0001-0207, Formaldehyde dimethyl acetal, absolute, over molecular sieve (H2O <=0.01%), >=99.0% (GC), Dimethoxymethane, Formal, Formaldehyde dimethylacetal, Methoxymethyl methyl ether, Methylene dimethyl ether, 2,4-Dioxapentane, Anesthenyl, Bis(methoxy)methane, Dimethoxymethane, Dimethyl formal, Formal, Formaldehyde dimethyl acetal, Formaldehyde dimethylacetal, Formaldehyde methyl ketal, Methane, dimethoxy-, Methoxymethyl methyl ether, Methylene dimethyl ether, UN1234,
dimethoxymethane, formaldehyde dimethylacetal, methoxymethyl methyl ether, methylene dimethyl ether, (CH3O)2CH2, 2,4-Dioxapentane, Anesthenyl, Bis(methoxy)methane, Dimethoxymethane, Dimethyl formal, Dimethylacetal formaldehyde, Formal, Formaldehyde dimethyl acetal, Formaldehyde methyl ketal,
Methane, dimethoxy-, Methoxymethyl methyl ether, Methylene dimethyl ether, Methylene glycol dimethylether, Methylenedioxydimethane, Metylal, UN 1234,
formaldehyde, dimethyl acetal, methanal, dimethyl acetal, 2,4-Dioxapentane, Anesthenyl, Bis(methoxy)methane, Dimethoxymethane, Dimethyl formal, Formal, Formaldehyde dimethyl acetal, Formaldehyde, methyl ketal, Methoxymethyl methylether, Methylal, Methylene dimethyl ether, Formaldehyde Dimethyl Ether, Dimethoxymethane, Formaldehyde dimethyl aceta, Dimethoxymethane, Formal, Formaldehyde Dimethylacetal, Methoxymethyl Methyl Ether, Methylene Dimethyl Ether,
Dimethoxymethane , Formal , Dimethyl Formal , Formaldehyde Dimethyl Acetal, 2,4-Dioxapentane, Anesthenyl, Bis(methoxy)methane, Dimethoxymethane, Dimethyl formal, Formal, Formaldehyde dimethyl acetal, Formaldehyde methyl ketal, Methoxymethyl methylether, Methylal, Methylene dimethyl ether, Dimethoxymethane, Formal, Formaldehyde dimethylacetal, Methoxymethyl methyl ether, Methylene dimethyl ether, 2,4-Dioxapentane, Anesthenyl, Bis(methoxy)methane, Dimethoxymethane, Dimethyl formal, Formal, Formaldehyde dimethyl acetal, Formaldehyde dimethylacetal, Formaldehyde methyl ketal, Methane, dimethoxy-, Methoxymethyl methyl ether, Methylene dimethyl ether, Metylal [Polish], [ChemIDplus] UN1234, Methane, dimethoxy-, Dimethyl formal, Anesthenyl, Dimethoxymethane, Formal, Formaldehyde dimethyl acetal, Methoxymethyl methyl ether, Methylene dimethyl ether, Methylene glycol dimethylether, (CH3O)2CH2, Methylenedioxydimethane, Metylal, UN 1234, Formaldehyde methyl ketal, 2,4-Dioxapentane, Dimethylacetal formaldehyde, Bis(methoxy)methane, Dimethoxymethane, Formal, Formaldehyde dimethyl ether, Methylal, Dimethylformal (DMFL), Formaldehyde dimethylacetal, Methoxymethyl methyl ether, Methylene dimethyl ether, METHYLAL, Methane dimethoxy, Anesthenyl, 2,4-Dioxapentane, Bis(methoxy)methane, Methylene glycol dimethylether, 7H1M4G2NUE, CHEBI:48341, Dimethoxy methane, MFCD00008495, HSDB 1820, UN1234, UNII-7H1M4G2NUE, AI3-16096, CCRIS 9397, Methylene Glycol Dimethyl Ether, Dimethoxy-Methane, Methylenedioxydimethane, Dimethylacetal formaldehyde, METHYLAL [HSDB], METHYLAL [INCI], METHYLAL [MI], METHYLAL [WHO-DD], EC 203-714-2, CHEMBL15537, DTXSID1025564, AKOS000120977, D0637, NS00003248, Q411496, J-520340, F0001-0207, UN 1234, formaldehyde dimethyl acetal, methanal dimethyl acetal, DIMETHYL FORMAL, DIMETHYLACETAL FORMALDEHYDE, METHOXYMETHYL METHYL ETHER, METHYLENE DIMETHYL ETHER, Dimethoxymethane, Dimethyl Formal, Formal, Formaldehyde Dimethyl Acetal, Dimethoxymethane, 109-87-5, METHYLAL, Formal, Methane dimethoxy, Formaldehyde dimethyl acetal, Dimethyl formal, Anesthenyl, 2,4-Dioxapentane, Methylene dimethyl ether, Bis(methoxy)methane, Methoxymethyl methyl ether, Metylal, Formaldehyde methyl ketal, Formaldehyde dimethylacetal, bis(methyloxy)methane, Methylene glycol dimethylether, 7H1M4G2NUE, CHEBI:48341, Dimethoxy methane, Metylal [Polish], MFCD00008495, HSDB 1820, EINECS 203-714-2, UN1234, UNII-7H1M4G2NUE, Dimethylformal, AI3-16096, CCRIS 9397, Methylene Glycol Dimethyl Ether, Dimethoxy-Methane, Methylenedioxydimethane, METHYLAL [HSDB], METHYLAL [MI], Dimethoxymethane 99.5%, Dimethylacetal formaldehyde, METHYLAL [WHO-DD], EC 203-714-2, CHEMBL15537, (CH3O)2CH2, DTXSID1025564, AKOS000120977, UN 1234, Dimethoxymethane, ReagentPlus(R), 99%, Methylal [UN1234], D0637, NS00003248, Formaldehyde dimethyl acetal, analytical standard, Q411496, J-520340, InChI=1/C3H8O2/c1-4-3-5-2/h3H2,1-2H, F0001-0207, Formaldehyde dimethyl acetal, absolute, over molecular sieve (H2O <=0.01%), >=99.0% (GC)



Methylal appears as a clear colorless liquid with a chloroform-like odor.
The flash point of Methylal is 0 °F.
The boiling point of Methylal is 42.3 °C.


The density of Methylal is 0.864 g / cm3 at 68 °F (20 °C).
Methylal is a colorless liquid with a low boiling point, low viscosity and excellent dissolving power.
Methylal has a chloroform-like odor and a pungent taste.


Methylal is the dimethyl acetal of formaldehyde.
Methylal is soluble in three parts water and miscible with most common organic solvents.
Methylal appears as a clear colorless liquid with a chloroform-like odor.


Flash point of Methylal is 0 °F.
Boiling point of Methylal is 42.3 °C.
Methylal's Vapors are heavier than air.


Methylal is an acetal that is the dimethyl acetal derivative of formaldehyde.
Methylal is an acetal and a diether.
Methylal is the dimethyl acetal of formaldehyde.


Methylal is soluble in three parts water and miscible with most common organic solvents
Methylal is a clear colorless liquid with a chloroform-like odor.
Methylal is soluble in water and miscible with common organic solvents like methanol and ethanol.


Methylal is a colorless liquid with the chemical formula C3H8O2.
Methylal is the dimethyl acetal of formaldehyde with unique properties, suitable for different applications.
Methylal is also known as formaldehyde dimethyl acetal, methylene dimethyl ether, and methoxymethyl methyl ether.


Methylal belongs to the following substance groups solvents.
Methylal is a colorless liquid with the chemical formula C3H8O2.
Methylal has a chloroform-like odor and a pungent taste.


Methylal is the dimethyl acetal of formaldehyde.
Methylal exhibits high solvent power, medium to low polarity/surface tension and low to high evaporation rate.
Methylal is functionally related to a methanediol.


Methylal is a colorless liquid.
Methylal is soluble in three parts water and miscible with most common organic solvents.
Methylal is primarily used as a solvent and in the manufacture of perfumes, resins, adhesives, paint strippers and protective coatings. Another useful application of Methylal is to protect alcohols with a MOM ether in organic synthesis.


Methylal is a colorless liquid with a chloroform-like odor.
Methylal is an ether.
Methylal is a partial substitute for alcohols in gel.


In formulations of antibacterial gel and hand sanitizers, Methylal can replace 50% of the alcohol used.
Alcohol is scarce and this can be partly dissolved by using Methylal.
Methylal, also known as Dimethoxymethane or Formaldehyde dimethyl ether, is the dimethyl acetal of formaldehyde used as a solvent as well as in manufacturing resins, perfumes, adhesives, and protective coatings.


Methylal is the triester of ethanol and phosphoric acid and can be called "phosphoric acid, triethyl ester".
Methylal is a clear colorless flammable liquid with a low boiling point, low viscosity and excellent dissolving power.
Density of Methylal is 0.864 g / cm3 at 68 °F (20 °C).


Vapors of Methylal is heavier than air.
Methylal is an acetal that is the dimethyl acetal derivative of formaldehyde.
Methylal is an acetal and a diether.


Methylal is functionally related to a methanediol.
Methylal is a colorless liquid with a harsh, sharp odor.
Methylal is a colorless yet highly volatile acetal solvent that is manufactured from Methanol.


Methylal has a chloroform-like odor and a pungent taste.
Methylal is the dimethyl acetal of formaldehyde.
Methylal is soluble in three parts water and miscible with most common organic solvents.


Another useful application of Methylal is to protect alcohols with a MOM ether in organic synthesis.
Methylal, is a colorless flammable liquid with a low boiling point, low viscosity and excellent dissolving power.
Methylal is a colorless liquid.


Methylal is the triester of ethanol and phosphoric acid and can be called "phosphoric acid, triethyl ester".
Methylal is a clear colorless flammable liquid with a low boiling point, low viscosity and an excellent dissolving power.
Methylal has a chloroform-like odor and a pungent taste.


Methylal is the dimethyl acetal of formaldehyde.
Methylal is a colorless yet highly volatile acetal solvent that is manufactured from Methanol.
Methylal has an extremely low toxicity profile.


Methylal is incompatible with strong oxidizing agents and acids.
Methylal should be kept away from heat, hot surfaces, sparks, open flames and other ignition sources.
Methylal is a colourless liquid with excellent dissolving power.


Methylal is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Methylal is a colorless flammable liquid with a low boiling point, low viscosity and excellent dissolving power.


Methylal has a chloroform-like odor and a pungent taste.
Methylal is a colorless liquid with a chloroform-like odor.



USES and APPLICATIONS of METHYLAL:
Methylal is used as a solvent for adhesives and coatings, a fuel, and an intermediate for other organic compounds.
Methylal has been used as an anesthetic.
Methylal can also be used for blending with diesel.


Methylal is often used as a fuel, to manufacture other organic chemicals, and a compatibilizer of actives in solvent and water based recipes.
In personal care applications, methylal improves spray performance and reduces solvent amount in aerosol cans and pump sprays. Methylal has an extremely low toxicity profile.


Methylal is used as a fuel and a solvent and to manufacture other organic chemicals.
Methylal is used aerosol cans & Pump sprays.
Methylal has a comparable, strong, dissolving capacity, which means that the quality of this substance can be found again.


In the case of Ethyl Alcohol, an improvement in quality is possible, when part of the alcohol is replaced by Methylal, smaller drop sizes are possible and the drying time is greatly shortened.
Further application of Methylal is possible in creams and lotions. The rapid evaporation creates a nice cooling effect.


This property, together with the high dissolving power for UV filters, makes the solvent very useful for sun protection products.
Removing nail polish with Methylal, possibly in combination with Dioxolane, is very effective.
Also as a replacement for Acetone or Ethyl Acetate, Methylal has no intoxicating effect when used on the hands, close to the face.


Methylal is used hand Cleansers, Antibacterial Gels, Hair Sprays, Sun Protection, Nail Polish Remover.
Industrially, Methylal is primarily used as a solvent and in the manufacture of perfumes, resins, adhesives, paint strippers and protective coatings.
Another application of Methylal is as a gasoline-additive for increasing octane number.


Methylal is often used as a fuel, to manufacture other organic chemicals, and a compatibilizer of actives in solvent and water based recipes.
Methylal is used as a solvent for adhesives and coatings, a fuel, and an intermediate for other organic compounds.
Methylal has been used as an anesthetic.


Methylal, or Dimethoxymethane, is a colorless liquid that acts as a solvent.
Methylal has a very strong dissolving capacity and can be used in many different applications.
Because of the rapid evaporation, Methylal is often used in aerosol cans, especially as a replacement for, for example, Methylene chloride or Ethyl alcohol.


Methylal is suitable for use in cosmetics, here it can be used in a number of product groups.
The most commonly used application is hair styling sprays, the Methylal is then usually used as a replacement for Methylene chloride or Ethyl alcohol (CAS 64-17-5).


Methylene chloride contains, among other things, the H351 (suspected carcinogen) warning and has been replaced by other solvents in cosmetic aerosol cans.
In personal care applications, Methylal improves spray performance and reduces solvent amount in aerosol cans and pump sprays.
Methylal is used in removing nail polish.


Methylal acts as a solvent and can be used in many different applications.
Methylal is used as a solvent in different industries.
Methylal is used to produce anion exchange resins, manufacture perfumes, paint stripping, etc.


Methylal is used reaction solvent manufacturing pharmaceuticals,
Adhesives, Gasoline-additive for increasing octane number, and Protective coatings.
Methylal is used Paint Stripping, and Aerosol cans.


Methylal is used as a solvent and in the manufacture of perfumes, resins, adhesives, paint strippers and protective coatings.
Methylal has a very strong dissolving capacity and is used as an extraction solvent in manufacturing pharmaceuticals, aerosols, paints, and varnishes.
Plus, Methylal is used as a fuel additive for smoke reduction.


Methylal, also known, as dimethoxymethane is widely used as a solvent and in the manufacture of perfumes, resins, adhesives.
Besides methylal is applied to increase the octane number of gasoline.
Methylal is primarily used as a solvent and in the manufacture of perfumes, resins, adhesives, paint strippers and protective coatings.


Methylal can be used in many different applications.
Due to the rapid evaporation, Methylal is often used in aerosol cans.
Plus, Methylal is suitable for use in cosmetics.


For example, Methylal is used in hair styling sprays, creams and lotions.
Methylal is mostly used as a solvent in different industries.
Methylal is used as a solvent in the manufacture of pharmaceuticals, aerosols, paints, varnishes and cleanings.


Methylal is used glue formulations fragrances and pesticides.
Methylal is used fuel additive for smoke reduction.
Methylal is used paint stripping.


Methylal is used in the production of creams and lotions. Methylal is a suitable solvent for sun protection products.
Methylal, also known, as dimethoxymethane is widely used as a solvent and in the manufacture of perfumes, resins, adhesives.
Release to the environment of Methylal can occur from industrial use: in processing aids at industrial sites, of substances in closed systems with minimal release, as an intermediate step in further manufacturing of another substance (use of intermediates) and for thermoplastic manufacture.


Release to the environment of Methylal can occur from industrial use: manufacturing of the substance.
Methylal is used in inks and coatings.
Methylal is a clear colourless liquid with a chloroform-like odour.


Methylal is soluble in water and is miscible with common organic solvents.
Methylal is used in different industries.
Methylal is used as a solvent in the manufacture of resins, adhesives, paint strippers and protective coatings.


Methylal is the dimethyl acetal of formaldehyde.
Methylal is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Methylal is used in the following products: coating products, air care products, lubricants and greases, fuels, washing & cleaning products, adhesives and sealants, biocides (e.g. disinfectants, pest control products), fillers, putties, plasters, modelling clay and polishes and waxes.
Other release to the environment of Methylal is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).


Other release to the environment of Methylal is likely to occur from: outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).


Besides Methylal is applied to increase the octane number of gasoline.
Methylal can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines).


Methylal is used in the following products: lubricants and greases, coating products, explosives, fuels, hydraulic fluids, laboratory chemicals, plant protection products, polymers and washing & cleaning products.
Methylal is used for the manufacture of: .


Other release to the environment of Methylal is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).
Release to the environment of Methylal can occur from industrial use: formulation of mixtures and formulation in materials.


Methylal is used in the following products: fuels, hydraulic fluids, lubricants and greases, polymers, coating products, heat transfer fluids, laboratory chemicals, washing & cleaning products and extraction agents.
Methylal has an industrial use resulting in manufacture of another substance (use of intermediates).


-Methylal is a product which can be today biosourced up to 86,5% with incredible properties which can fit in various applications to optimize:
*Wetting
*Viscosity
*Drying time (in spray and aerosols)
*Solubilization of ingredients (resins, actives, grease,..)
That's really the key polyvalent product to improve performances of your formulations.
Moreover, Methylal is only flammable and not label for health or environment issue



SYNTHESIS AND STRUCTURE OF METHYLAL:
Methylal can be manufactured by oxidation of methanol or by the reaction of formaldehyde with methanol.
In aqueous acid, Methylal is hydrolyzed back to formaldehyde and methanol.

Due to the anomeric effect, Methylal has a preference toward the gauche conformation with respect to each of the C–O bonds, instead of the anti conformation.

Since there are two C–O bonds, the most stable conformation is gauche-gauche, which is around 7 kcal/mol more stable than the anti-anti conformation, while the gauche-anti and anti-gauche are intermediate in energy.
Since it is one of the smallest molecules exhibiting this effect, which has great interest in carbohydrate chemistry, Methylal is often used for theoretical studies of the anomeric effect.



METHYLAL MARKET OVERVIEW:
Methylal Market is forecast to reach $445 million by 2026, after growing at a CAGR of 1.5% during the forecast period from 2021-2026.
Methylal is also known as dimethoxymethane and is often produced by oxidizing methanol or through the reaction of formaldehyde and methanol.

Globally, rising demand for methylal as blowing agents for PU foams, growing pharmaceuticals industries, flourishing cosmetic industry, and extensive properties of methylal such as good solubility, low boiling point, and anti-carcinogenic are the prime growth drivers of the methylal market.

In addition, the emergence of methylal as an automotive fuel and diesel modification additive, increase in the adoption of methylal for application in newer industrial verticals will create new opportunities for the methylal market, which will then substantially drive the methylal market during the forecast period.



FUNCTIONS OF METHYLAL IN COSMETIC PRODUCTS:
*SOLVENT
Methylal dissolves other substances



PRODUCTION OF METHYLAL:
Methylal is produced through the reaction of methanol and formaldehyde in the presence of concentrated sulfuric acid.
The resultant methylal is distilled, and unreacted methanol is separated from the product for recycling to obtain methylal with a content of 85% or more.



ADVANTAGES OF METHYLAL:
*Excellent Stability
*A versatile replacement solvent
*Excellent water removal property from organic molecules
*Excellent stability in acidic or alkaline medium
*Good miscibility with water



ADVANTAGES OF METHYLAL INCLUDE:
*Excellent stability
*Excellent water removal property from organic molecules
*Rapid evaporation
*Low viscosity
*Excellent dissolving power



SOME PROPERTIES OF METHYLAL INCLUDE:
*Methylal's molar mass is 09 g. mol-1.
*Methylal's melting point is −105 °C.
*Methylal's boiling point is 42 °C.
*Methylal's density is 821 gcm–3



REAGENT IN ORGANIC SYNTHESIS OF METHYLAL:
Another useful application of Methylal is to protect alcohols with a methoxymethyl (MOM) ether in organic synthesis.
Methylal can be activated with phosphorus pentoxide in dichloromethane or chloroform.

This method is preferred to the use of chloromethyl methyl ether (MOMCl).
Phenols can also be MOM-protected using Methylal, p-toluenesulfonic acid.
Alternatively, MOMCl can be generated as a solution by treating Methylal with an acyl chloride in the presence of a Lewis acid catalyst like zinc bromide:

MeOCH2OMe + RC(=O)Cl → MeOCH2Cl + RC(=O)(OMe)).
Unlike the classical procedure, which uses formaldehyde and hydrogen chloride as starting materials, the highly carcinogenic side product bis(chloromethyl) ether is not generated



PRODUCTION OF METHYLAL:
Methylal is produced through the reaction of methanol and formaldehyde in the presence of an acidic catalyst.
Methylal is generally known that methylal can be produced in the presence of sulfuric acid.
Conventionally, the methylal production is of batch process in which reaction and product isolation are carried out separately.



STORAGE OF METHYLAL:
Methylal is an important raw material and an excellent solvent in industry.
Methylal should be kept separated from strong oxidants and strong bases.
Plus, Methylal should be stored in a cool, dry, and well-ventilated facility.



OTHER STORAGE CONDITIONS OF METHYLAL INCLUDE:
Methylal should be stored in an area without drain or sewer access.
Methylal should be stored away from direct sunlight.

Methylal should be stored in tightly closed containers.
Methylal should be stored away from incompatible substances.
Methylal should be kept away from heat, sparks, and flame.



STORAGE OF METHYLAL:
Methylal should be stored in a tightly closed container, away from direct sunlight.
Methylal should be stored in a cool, dry and well-ventilated facility away from incompatible substances.
Methylal should be kept away from heat, sparks, and flame.



INFORMATION ABOUT METHYLAL:
"Methyl" mostly refers to methanol (methyl alcohol) as alcoholic component or generally the methyl group as the smallest hydrocarbon residue with one carbon atom.
Dimethyl-, trimethyl- etc refer to two, three or more methyl groups.



PHYSICAL and CHEMICAL PROPERTIES of METHYLAL:
Beilstein Number: 1697025
MDL: MFCD00008495
CoE Number: 10031
XlogP3: 0.20 (estimated)
Molecular Weight: 76.09516000
Formula: C3H8O2
Appearance: Colorless clear liquid (estimated)
Assay: 95.00 to 100.00%
Water Content: ~0.1%
Food Chemicals Codex Listed: No
Specific Gravity: 0.85500 to 0.86200 @ 25.00 °C
Pounds per Gallon - (estimated): 7.114 to 7.173
Refractive Index: 1.35000 to 1.35600 @ 20.00 °C

Melting Point: -105.00 °C @ 760.00 mm Hg
Boiling Point: 42.00 °C @ 760.00 mm Hg
Vapor Pressure: 398.000000 mmHg @ 25.00 °C
Flash Point: 1.00 °F TCC (-17.22 °C)
Soluble in alcohol, water (244000 mg/L @ 16°C, experimentally determined)
Physical description: Colorless liquid with a chloroform-like odor.
Boiling point: 111°F
Molecular weight: 76.1
Freezing point/melting point: -157°F
Vapor pressure: 330 mmHg
Flash point: -26°F (open cup)
Vapor density: 2.6
Specific gravity: 0.86

Ionization potential: 10.00 eV
Lower explosive limit (LEL): 1.6%
Upper explosive limit (UEL): 17.6%
NFPA health rating: 1
NFPA fire rating: 3
NFPA reactivity rating: 1
EINECS: 203-714-2
Density: 0.8560 g/cm3
Melting Point: -104.8°C
Boiling Point: 45.238 °C at 760 mmHg
Vapor Pressure: 43.99 kPa at 20 °C
Flash point: -17.8 °C
Explosion Limits, Lower: 1.60 vol%
Explosion Limits, Upper: 17.60 vol%

Molecular formula: C3H8O2
Molecular weight: 76.08 g/mol
CAS number: 109-87-5
EC number: 203-714-2
IUPAC name: Dimethoxymethane
EC name: Dimethoxymethane
EINECS: 203-714-2
Density: 0.8560 g/cm3
Freezing Point/Melting Point: -104.8°C
Boiling Point: 45.238 °C at 760 mmHg
Vapor Pressure: 43.99 kPa at 20 °C
Flash point: -17.8 °C
Explosion Limits, Lower: 1.60 vol%
Upper: 17.60 vol%
Appearance: Colorless transparent liquid

CSA Number: 109-87-5
Molecular Formula: C3H8O2
Molecular Weight: 76.09 g/mol
Appearance: Clear colorless liquid
Flash point: 180°C
Boiling Point: 42°C-44°C
Freezing Point/Melting Point: 105°C
Auto Ignition Temperature: 237°C
IUPAC name: Dimethoxymethane
CAS Number: 109-87-5
Density: 0.821 g/cm3
Boiling Point: 42 °C
Flashpoint: -31 °C
Melting Point: −105 °C

Chemical formula: C3H8O2
Molar mass: 76.095 g•mol−1
Appearance: Colorless liquid
Odor: Chloroform-like
Density: 0.8593 g cm−3 (at 20 °C)
Melting point: −105 °C (−157 °F; 168 K)
Boiling point: 42 °C (108 °F; 315 K)
Solubility in water: 33% (20 °C)
Vapor pressure: 330 mmHg (20 °C)
Magnetic susceptibility (χ): −47.3•10−6 cm3/mol
Molecular Weight: 76.09 g/mol
XLogP3: 0.2

Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 2
Exact Mass: 76.052429494 g/mol
Monoisotopic Mass: 76.052429494 g/mol
Topological Polar Surface Area: 18.5Ų
Heavy Atom Count: 5
Formal Charge: 0
Complexity: 12.4
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Molecular formula: C3H8O2
Molecular weight: 76,08
CAS number: 109-87-5
EC number: 203-714-2
IUPAC name: Dimethoxymethane
EC name: Dimethoxymethane
Boiling point (°C) at 1013 hPa: 42.3
Freezing point (°C) at 1013 hPa: -104.8
Flash-point (°C) at 1013 hPa :-30.5
Relative density at 20°C: 0.861

Vapour pressure (kPa) at 20°C: 40
Surface tension (mN/m) at 20°C: 21.2
Water solubility (g/L) at 20°C Methylal in water: 330
Viscosity (kinematic) (mm²/s) at 25°C: 0.371
Evaporation rate compared to Diethyl ether (= 1): 1.36
Butyl acetate (= 1): 0.11
Physical state: clear, liquid
Color: colorless
Odor: pungent
Melting point/freezing point:
Melting point/range: -105 °C - lit.
Initial boiling point and boiling range: 41 - 42 °C - lit.

Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 19,9 %(V)
Lower explosion limit: 2,2 %(V)
Flash point: -18 °C - closed cup
Autoignition temperature: 260 °C at 1.013 hPa
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 0,325 mPa.s at 20 °C
Water solubility 330 g/l at 20 °C - soluble
Partition coefficient: n-octanol/water: No data available
Vapor pressure: 439,8 hPa at 20 °C 1.548,8 hPa at 55 °C

Density: 0,86 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 21,2 mN/m at 20 °C
Relative vapor density: 2,63 - (Air = 1.0)
Boiling point: 111°F
Molecular weight: 76.1

Freezing point/melting point: -157°F
Vapor pressure: 330 mmHg
Flash point: -26°F (open cup)
Vapor density: 2.6
Specific gravity: 0.86
Ionization potential: 10.00 eV
Lower explosive limit (LEL): 1.6%
Upper explosive limit (UEL): 17.6%
NFPA health rating: 1
NFPA fire rating: 3
NFPA reactivity rating: 1



FIRST AID MEASURES of METHYLAL:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water. Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of METHYLAL:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area



FIRE FIGHTING MEASURES of METHYLAL:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of METHYLAL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Splash contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 120 min
*Body Protection:
Flame retardant antistatic protective clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of METHYLAL:
-Precautions for safe handling:
*Hygiene measures:
Change contaminated clothing.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Handle and open container with care.



STABILITY and REACTIVITY of METHYLAL:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .


METHYLCHLOROISOTHIAZOLINONE (MCI)
Methylchloroisothiazolinone (MCI), also referred to as MCI, is the organic compound with the formula S(C2HCl)C(O)N(CH3).
Methylchloroisothiazolinone (MCI) is a white solid that melts near room temperature.
Methylchloroisothiazolinone (MCI) is an isothiazolinone, a class of heterocycles used as biocides.

CAS: 26172-55-4
MF: C4H4ClNOS
MW: 149.6
EINECS: 247-500-7

Synonyms
4-Isothiazolin-3-one,5-chloro-2-methyl-;5-chloro-2-methyl-3(2h)-isothiazolon;5-chloro-2-methyl-4-isothiazolin-3-on;Isothiazolinone;5-Chloro-2-methyl-4-isothiazolinone;5-CHLORIDE-2-METHYL-4-ISOTHIAZOLINE-3-KETONE;5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE (CMI);5-CHLORO-2-METHYL-3(2H)-ISOTHIAZOLONE MIXED WITH 2-METHYL-3(2H)ISOTHIAZOLONE;5-Chloro-2-methyl-4-isothiazolin-3-one;26172-55-4;Methylchloroisothiazolinone;CMIT;Chloromethylisothiazolinone;5-Chloro-2-methyl-3(2H)-isothiazolone;5-Chloro-2-methyl-3-isothiazolone;3(2H)-Isothiazolone, 5-chloro-2-methyl-;5-Chloro-2-methyl-2H-isothiazol-3-one;5-chloro-N-methylisothiazolone;5-chloro-2-methylisothiazolin-3-one;5-chloro-2-methylisothiazol-3(2h)-one;5-chloro-n-methylisothiazolin-3-one;HS 818;n-methyl-5-chloroisothiazolone;5-chloro-2-methyl-1,2-thiazol-3-one;4-ISOTHIAZOLIN-3-ONE, 5-CHLORO-2-METHYL-;5-chloro-2-methyl-4-isothiazoline-3-one;DEL7T5QRPN;N-Methyl-5-chloroisothiazolin-3-one;5-chloro-2-methyl-3(2H)-isothiazolinone;DTXSID9034286;CHEBI:53621;2,3-Dihydro-2-methyl-3-oxo-5-chloroisothiazole;Kathon CG 5243;NCGC00181041-01;Bioace;5-chloro-2-methyl-1,2-thiazol-3(2H)-one;5-Chloro-2-methyl-3-isothiazolone (~90%);Kathon IXE;5-Chloro-2-methyl-4-isothiazolin-3-one, tech grade, >14% in water. CMI/MI >2.0;5-chloro-2-methyl-2,3-dihydro-1,2-thiazol-3-one;DTXCID7014286;5-Chloro-2-methyl-4-isothiazolin-3-one 100 microg/mL in Acetonitrile;N-Methyl-5-chloroisothiazolone (5-Chloro-2-methyl-4-isothiazolin-3-one);CAS-26172-55-4;A 33 (bactericide);UNII-DEL7T5QRPN;HS 818 (antiseptic);EINECS 247-500-7;BRN 1210149;5-Chloro-2-methyl-4-isothiazolin-3-one D3 (methyl D3);2-Methyl-5-chloro-3-isothiazolone;5-chloro-2-methyl-isothiazol-3-on;2-Methyl-5-chloroisothiazolin-3-one;5-chloro-2-methyl-2h-isothiazolin-3-one;T 360;SCHEMBL20686;SCHEMBL111860;CHEMBL1738962;HSDB 8270;Tox21_112689;Tox21_300199;HS-818;MFCD00792550;AKOS006230760;1ST2157;CS-W022348;DB14197;GS-3223;METHYLCHLOROISOTHIAZOLINONE [II];METHYLCHLOROISOTHIAZOLINONE [MI];5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE (ACTIVE INGREDIENT >14%, CMI/MI 2.5 - 4.0);NCGC00181041-02;NCGC00254127-01;55965-84-9 CMIT, MIT;AM806586;METHYLCHLOROISOTHIAZOLINONE [VANDF];2682-20-4 MIT;5-Chloro-2-methyl-isothiazol-3(2H)-one;METHYLCHLOROISOTHIAZOLINONE [MART.];DB-007017;METHYLCHLOROISOTHIAZOLINONE [WHO-DD];NS00000256;5-CHLOR-2-METHYL-4-ISOTHIAZOLIN-3-ONE;H10371;SBI-0654074.0001;EN300-7409393;Q204121;SR-01000944864;SR-01000944864-1;W-107193;Z2417817741;5-Chloro-2-methyl-4-isothiazolin-3-one (CMI/MI > 2.0)

Methylchloroisothiazolinone (MCI) have an active sulphur moiety that is able to oxidize thiol-containing residues, thereby effectively killing most aerobic and anaerobic bacteria.
Methylchloroisothiazolinone (MCI) is often used in combination with methylisothiazolinone, a mixture known as Kathon.
The Methylchloroisothiazolinone (MCI) have attracted attention because they can cause contact dermatitis.
Methylchloroisothiazolinone (MCI) is effective against gram-positive and gram-negative bacteria, yeast, and fungi.
Methylchloroisothiazolinone (MCI) is a heterocyclic chemical compound related to isothiazole.
Methylchloroisothiazolinone (MCI) is an antimicrobial preservative that is often used to control fungi, bacteria, and algae.

Since water-containing solutions are the breeding grounds for bacteria, Methylchloroisothiazolinone (MCI) can easily be used in such solutions.
Methylchloroisothiazolinone (MCI) is contained, along with methylisothiazolinone (MI), in Kathon cosmetic grade (CG) and MCI/MI.
Methylchloroisothiazolinone (MCI) is irritant and sensitizer.
A Methylchloroisothiazolinone (MCI) bearing a methyl group on the nitrogen atom and a chlorine at C-5.
Methylchloroisothiazolinone (MCI) is a powerful biocide and preservative and is the major active ingredient in the commercial product KathonTM.

Methylchloroisothiazolinone (MCI) is a 1,2-thiazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom and a chlorine at C-5.
Methylchloroisothiazolinone (MCI) is a powerful biocide and preservative and is the major active ingredient in the commercial product Kathon(TM).
Methylchloroisothiazolinone (MCI) has a role as an antimicrobial agent, a xenobiotic and an environmental contaminant.
Methylchloroisothiazolinone (MCI) is a member of 1,2-thiazoles and an organochlorine compound.
Methylchloroisothiazolinone (MCI) is functionally related to a methylisothiazolinone.
Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and antifungal properties.
Methylchloroisothiazolinone (MCI) is found within many commercially available cosmetics, lotions, and makeup removers.
Methylchloroisothiazolinone (MCI) is also a known dermatological sensitizer and allergen; some of its side effects include flaky or scaly skin, breakouts, redness or itchiness, and moderate to severe swelling in the eye area.

Methylchloroisothiazolinone (MCI) Chemical Properties
Melting point: 42-45C
Boiling point: 109.7°C
Density: 1.25 (14% aq.)
Refractive index: n20/D 1.378
Storage temp.: Refrigerator
Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
pka: -4.06±0.40(Predicted)
Form: Liquid
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: 0.240 (est)
CAS DataBase Reference: 26172-55-4(CAS DataBase Reference)
NIST Chemistry Reference: Methylchloroisothiazolinone (MCI)(26172-55-4)
EPA Substance Registry System: Methylchloroisothiazolinone (MCI) (26172-55-4)

Applications
Although Methylchloroisothiazolinone (MCI) have no direct applications, their derivatives such as 5-chloro-2-methyl-4-isothiazolin-3-on and 2-methyl-4-isothiazolin-3 which are used together as preservatives in commercial households and cosmetics products, for instance, cleaners, shampoos, and washing materials.
Notably, various products that use Methylchloroisothiazolinone (MCI) are in the market, including shampoo, hand sanitizer, and lotions.
Methylchloroisothiazolinone (MCI) is used in these products as an inhibitor of microbial activity that could lead to the product spoiling before the expected expiration date.
Methylchloroisothiazolinone (MCI) is a high performance biocide for preserving metal working fluids, hydraulic fluids, polymer emulsions, pigment dispersions.

Suggested applications: preservative concentrate.
Very low level.
Methylchloroisothiazolinone (MCI) is a cost-effective antimicrobial for personal care formulations.
Suggested applications: personal care preservative.
Methylchloroisothiazolinone (MCI) is a high performance industrial microbiocide for use in recirculating water cooling towers, wood, mold and mildew control, pulp and paper mills, air washer systems.
Suggested applications: Industrial water treatment.
Very low use levels.
A Methylchloroisothiazolinone (MCI) derivative as antimicrobial.
Methylchloroisothiazolinone (MCI) was tested for inhibition of PCAF activity. 5-Methylchloroisothiazolinone (MCI) showed the most potent inhibition of PCAF.

Methylchloroisothiazolinone (MCI) is found in many water-based personal care products and cosmetics.
Methylchloroisothiazolinone (MCI) was first used in cosmetics in the 1970s.
Methylchloroisothiazolinone (MCI) is also used in glue production, detergents, paints, fuels, and other industrial processes.
Methylchloroisothiazolinone (MCI) is known by the registered tradename Kathon CG when used in combination with methylisothiazolinone.
Methylchloroisothiazolinone (MCI) may be used in combination with other preservatives including ethylparaben, benzalkonium chloride, bronopol and phenoxyethanol.

Hazards
Methylchloroisothiazolinone (MCI) can cause allergic reactions in some people.
The first publication of the preservative as a contact allergen was in 1988.
Cases of photoaggravated allergic contact dermatitis, i.e. worsening of skin lesions after sun exposure, have also been reported.
In pure form or in high concentrations, Methylchloroisothiazolinone (MCI) is a skin and membrane irritant and causes chemical burns.
In the United States, maximum authorized concentrations are 15 ppm in rinse-offs (of a mixture in the ratio 3:1 of 5-chloro-2-methylisothiazol 3(2H)-one and 2-methylisothiazol-3 (2H)-one).
In Canada, Methylchloroisothiazolinone (MCI) may only be used in rinse-off products in combination with methylisothiazolinone, the total concentration of the combination may not exceed 15 ppm.
Methylchloroisothiazolinone
N° CAS : 35691-65-7, Nom INCI : METHYLDIBROMO GLUTARONITRILE. Conservateur : Inhibe le développement des micro-organismes dans les produits cosmétiques.2-bromo-2-(bromomethyl)pentanedinitrile (DBDCB), Synonymes : methyldibromoglutaronitrile;Glutaronitrile, 2-bromo-2-(bromomethyl)-;1,2-Dibromo-2,4-dicyanobutane;2-Bromo-2-(bromomethyl)pentanedinitrile;1-bromo-(bromoethyl)-1,3-propanedicarbonitrile;1-Bromo-1-(bromomethyl)-1,3-propanedicarbonitrile;2, 3-Dibromo-2,4-cyanobutane;2-Bromo-2-(bromomethyl) pentanedinitrile;2-Bromo-2-(bromomethyl)glutaronitrile;Dibromodicyanobutane;MDBGN;Metacide 38;Pentanedinitrile, 2-bromo-2-(bromomethyl)-;Tektamer 38;USEPA/OPP Pesticide Code: 111001.
METHYLDIBROMO GLUTARONITRILE
N° CAS : 105-59-9, Nom INCI : METHYL DIETHANOLAMINE, Nom chimique : N-Methyldiethanolamine, METHYL DIETHANOLAMINE, Noms français : 2,2'-Methyliminodiethanol; Diethanolmethylamine; Méthyl diethanolamine; Méthylimino diéthanol-2,2'; N-Methyldiethanolamine; N-Méthyl diéthanolamine. Noms anglais : Ethanol, 2,2'-(methylimino)bis-; Methyldiethanolamine ,2'-(Methylimino)diethanol, 2,2'-Methyliminodiethanol, 2,2`-(Methylimino)bis-ethanol, 2-(N-2-Hydroxyethyl-N-methylamino)ethanol, 2-[2-hydroxyethyl(methyl)amino]ethanol, 4-04-00-01517 (Beilstein Handbook Reference), Bis(2-hydroxyethyl) methyl amine, Bis(2-hydroxyethyl)methylamine, C5H13NO2, Diethanolmethylamine, EINECS 203-312-7, Ethanol, 2,2'-(methylimino)bis-, Ethanol, 2,2'-(methylimino)di-, LS-389, MDEA, Methylbis(2-hydroxyethyl)amine, Methyldiethanolamine, Methyliminodiethanol, N,N-Bis(2-hydroxyethyl)methylamine, N,N-Di(2-hydroxyethyl)-N-methylamine, N-Methyl-2,2'-iminodiethanol, N-Methylaminodiglycol, N-METHYLDIETHANOLAMINE, n-methyl diethanolamine,N-Methyldiethanolimine, N-Methylimino-2,2'-diethanol, N-Methyliminodiethanol,N° EINECS/ELINCS : 203-312-7. Ses fonctions (INCI) : Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles. Noms français : 2,2'-Methyliminodiethanol; Diethanolmethylamine; Méthyl diethanolamine; Méthylimino diéthanol-2,2'; N-Methyldiethanolamine; N-Méthyl diéthanolamine. Noms anglais : Ethanol, 2,2'-(methylimino)bis-; Methyldiethanolamine
METHYLDIETHANOLAMINE
Methyldiethanolamine is a colorless liquid.
Methyldiethanolamine is a colorless to yellow liquid tertiary amine compound with an ammonia-like odor.
Methyldiethanolamine is a dihydroxy functional tertiary amine.


CAS Number: 105-59-9
EC Number: 203-312-7
MDL number: MFCD00002848
Molecular Formula: C5H13NO2 / CH3N(C2H4OH)2


Methyldiethanolamine is a colorless liquid.
Methyldiethanolamine is very water soluble .
Methyldiethanolamine is a clear, Colorless or Pale Yellow liquid with Ammonical Odor.


Methyldiethanolamine is miscible with water, alcohol and benzene.
Methyldiethanolamine is also known as a MDEA or N-Methyl Diethanolamine.
Methyldiethanolamine is versatile bifunctional molecules compound that combines the characteristic of Amine and hydroxyl group.


So, during the reaction, Methyldiethanolamine behaves like Alcohol and Amine Group but Amine group usually exhibits the greater activities.
Methyldiethanolamine can be modified with the help of some additives, the product is known as an activated Methyl Diethanolamine.
Methyldiethanolamine is a tertiary amine.


Methyldiethanolamine is capable of undergoing reactions typical of both alcohols and amines, forming Quaternary amine salts, soaps, and esters.
Methyldiethanolamine is an alkyl alkanolamine that is used in gas treatment applications and serves as an intermediate in the synthesis of numerous products.


Methyldiethanolamine is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Methyldiethanolamine is a colorless to yellow liquid tertiary amine compound with an ammonia-like odor.


Methyldiethanolamine is completely soluble in water.
Methyldiethanolamine is a dihydroxy functional tertiary amine.
Methyldiethanolamine is a versatile intermediate with a variety of applications.


Methyldiethanolamine is a versatile, polyfunctional molecule that combines thecharacteristics of amines and alcohols.
Methyldiethanolamine is a colorless or dark yellow oily liquid.
Freezing point of Methyldiethanolamine is -21 °c.


Boiling point of Methyldiethanolamine is 247.2 °c.
Flash point of Methyldiethanolamine is 260 °c.
The relative density of Methyldiethanolamine was 1. 0377.


Refractive index of Methyldiethanolamine is 4678.
Methyldiethanolamine is miscible with water and alcohol.
Methyldiethanolamine is slightly soluble in ether.



USES and APPLICATIONS of METHYLDIETHANOLAMINE:
Methyldiethanolamine is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Methyldiethanolamine is used in the following products: washing & cleaning products.


Other release to the environment of Methyldiethanolamine is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Methyldiethanolamine can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones).
Methyldiethanolamine is used in the following products: coating products, lubricants and greases, metal working fluids, polymers, laboratory chemicals, pH regulators and water treatment products and washing & cleaning products.


Methyldiethanolamine is used in the following areas: building & construction work and scientific research and development.
Methyldiethanolamine is used for the manufacture of: and plastic products.
Other release to the environment of Methyldiethanolamine is likely to occur from: indoor use as processing aid.


Other release to the environment of Methyldiethanolamine is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Methyldiethanolamine is used in the following products: polymers.


Release to the environment of Methyldiethanolamine can occur from industrial use: formulation of mixtures.
Methyldiethanolamine is used in the following products: laboratory chemicals, coating products, pH regulators and water treatment products, lubricants and greases, metal working fluids and polymers.


Release to the environment of Methyldiethanolamine can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release, in the production of articles and as processing aid.


Release to the environment of Methyldiethanolamine can occur from industrial use: manufacturing of the substance.
Methyldiethanolamine is used as a co-initiator for type II photoinitiator combinations.
As a neutralizing agent, Methyldiethanolamine increases resin solubility and improves solution stability by reducing pH drift.


Additionally, Methyldiethanolamine aids pigment dispersion.
Foams and Elastomers: Methyldiethanolamine can be used as a chain extender during the synthesis of polyol-based polyurethane foams and elastomers.
Inks: Methyldiethanolamine is used as a co-initiator for type II photoinitiator combinations.


As a neutralizing agent, Methyldiethanolamine increases resin solubility and improves solution stability by reducing pH drift. Additionally, Methyldiethanolamine aids pigment dispersion.
Metal Working: In metal working fluids, Methyldiethanolamine is used both as a pH buffer as well as an anticorrosion additive.


Textiles: Methyldiethanolamine forms quat salts with fatty acids which then find application in fabric softener formulations.
Methyldiethanolamine is used Urethanes, Paper Chemicals, Textile Softners, Pharmaceuticals, Gas scrubbing (CO2, H2S removal in natural, refining gas, ammonia hydrogen unit), Dyes and Polyurethane


Methyldiethanolamine is also a precursor to mechlorethamine (Bis(2-chloroethyl)methylamine), a nitrogen mustard chemical warfare agent developed for use as a vesicant or blister agent, similar to sulfur mustards.
Itself a dual-use chemical, Methyldiethanolamine has also been used as a chemotherapy agent in the treatment of Hodgkin lymphoma, leukaemia, and lung cancer.


Methyldiethanolamine is used in the following areas: building & construction work and scientific research and development.
Methyldiethanolamine is used for the manufacture of: chemicals, and plastic products.
Uses of Methyldiethanolamine: component of metal-working fluids; industrial chemical intermediate; corrosion inhibitor


Methyldiethanolamine is used as an intermediate in the synthesis of numerous products.
Methyldiethanolamine's unique chemistry has resulted in its use in diverse areas, including coatings, textile lubricants, polishes, detergents, pesticides, personal-care products, pharmaceuticals, urethane catalysts, and water-treatment chemicals.


Methyldiethanolamine is also used in absorption of acidic gases, catalyst for polyurethane foams, pH control agent.
Methyldiethanolamine is a reagent used for protection of boronic acids as N-methyl-O,O-diethanolamine esters.
Methyldiethanolamine is capable of undergoing reactions typical of both alcohols and amines, forming Quaternary amine salts, soaps, and esters.


This makes Methyldiethanolamine a useful intermediate in the synthesis of numerous products, and has resulted in its use in many diverse areas, including coatings, textile lubricants, polishes, detergents,pesticides, personal care products, and pharmaceuticals.
Methyldiethanolamine is widely used as a decarbonizer and Sweating agent in chemical, oil refinery, Gas synthesis, Natural gas & gas.


Methyldiethanolamine is more efficient absorber then MEA & DEA for sulphur contains impurity and acid gases found in natural gas processing.
Textiles : Methyldiethanolamine is used in manufacturing of softener, soap emulsifying agent, Lubricants, Paraffin Emulsion and dyes.
Pharmaceuticals: In synthesis of analgesics and the intermediate product for some products.


Gas absorbent : Purifies the gases particularly natural gas for the bulk removable of Carbon Dioxide and also used as a scrubbing and extracting agent in Gas treatment.
Catalyst : Effective catalyst for urethane and epoxy resin coating system.


Formulators : Methyldiethanolamine is used in lubricating oil, hydraulic fluids, corrosion inhibitor, refractory binder, surface active agent, solvent in water paint formula, Herbicides, Pesticides formulation and for PH control.
Methyldiethanolamine is used as an intermediate, to absorb acidic gases, as catalyst for polyurethane foams, and pH control agent.


Methyldiethanolamine is used in chemical syntheses (i.e. pharmaceuticals and cationic surfactants), as a cleaning-washing agent, pH regulator (coating manufacture), and solvent (removal of acid gases in oil refineries)
Methyldiethanolamine is used to make fine and large scale chemicals, as a catalyst in polymerization reactions, laboratory reagent, additive in coatings and concrete-cement, in gas treatment, and lubricants and metalworking fluids.


Methyldiethanolamine is permitted for use as an inert ingredient in non-food pesticide products;
Methyldiethanolamine is a new solvent with excellent performance for selective desulfurization and decarburization.
Methyldiethanolamine has the advantages of high selectivity, less solvent consumption, remarkable energy saving effect, and not easy to degrade.


Methyldiethanolamine is widely used in oil gas and gas desulfurization purification emulsifier and acid gas absorbent, acid-base control agent, polyurethane foam catalyst.
The carbon dioxide in synthetic ammonia can be removed with the participation of an activator, so that Methyldiethanolamine has been gradually promoted in the absorption of carbon dioxide in flue gas in recent years.


In addition, Methyldiethanolamine can also be used as pesticides, emulsifiers, semi-finished products of fabric additives, intermediates of antineoplastic drug hydrochloric acid nitrogen mustard, catalyst of carbamate coatings, it is also a drying accelerator for paint.
Methyldiethanolamine is mainly used as an emulsifier and an absorbent of acid gas, and is also used as an intermediate for antitumor drugs.


Methyldiethanolamine is used Pharmaceuticals, Water treatment, Fabric treatment, Coatings, and Gas treatment
Commercial Uses: Methyldiethanolamine is known by at least 93 different synonyms3 and has many commercial applications, including in the manufacture of construction and building materials, ink for inkjet printers, film forming, and as a component in fragrances.



BENEFITS OF METHYLDIETHANOLAMINE:
*Versatile
*Polyfunctional
*Combine characteristics of amines and alcohols



REACTIVITY PROFILE OF METHYLDIETHANOLAMINE:
Methyldiethanolamine is an aminoalcohol.
Amines are chemical bases.
They neutralize acids to form salts plus water.
These acid-base reactions are exothermic.
The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base.
Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Methyldiethanolamine may react with oxidizing materials.



PREPARATION OF METHYLDIETHANOLAMINE:
N-methyldiethanolamine is produced by the reaction between ethylene oxide and methylamine.
Preparation of N-methyldiethanolamine



CHEMICAL PROPERTIES OF METHYLDIETHANOLAMINE:
Methyldiethanolamine is a colorless to yellow viscous liquid with an ammonia-like odor.
Methyldiethanolamine is completely soluble in water.
Methyldiethanolamine is an alkyl alkanolamine.
Methyldiethanolamine combines the chemical characteristics of both amines and alcohols so that it is capable of undergoing reactions typical of both alcohols and amines: forming quaternary amine salts, soaps, and esters.



PHYSICAL AND CHEMICAL PROPERTIES OF METHYLDIETHANOLAMINE:
*colorless or yellowish viscous liquid
*boiling point 246~248 ℃
*flash point 260 ℃
*freezing point -21 ℃
*latent heat of vaporization 519.16KJ/Kg
*boiling point 247 ℃
*water-soluble, soluble in water and alcohol, slightly soluble in ether



PHYSICAL and CHEMICAL PROPERTIES of METHYLDIETHANOLAMINE:
Molecular Weight: 119.16 g/mol
XLogP3-AA: -1.1
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 4
Exact Mass: 119.094628657 g/mol
Monoisotopic Mass: 119.094628657 g/mol
Topological Polar Surface Area: 43.7Ų
Heavy Atom Count: 8
Formal Charge: 0
Complexity: 43.7
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical formula: C5H13NO2
Molar mass: 119.164 g·mol−1

Appearance: Colorless liquid
Odor: Ammoniacal
Density: 1.038 g mL−1
Melting point: −21.00 °C; −5.80 °F; 252.15 K
Boiling point: 247.1 °C; 476.7 °F; 520.2 K
Solubility in water: Miscible
Vapor pressure: 1 Pa (at 20 °C)
Refractive index (nD): 1.4694
Viscosity: 101 mPa s (at 20°C)
Physical state: clear, viscous liquid
Color: light yellow
Odor: ammoniacal
Melting point/freezing point:
Melting point/range: -21,3 °C
Initial boiling point and boiling range: 246 - 248 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 8,8 %(V)
Lower explosion limit: 1,4 %(V)
Flash point 127 °C - closed cup
Autoignition temperature: 280 °C at 1.013 hPa
Decomposition temperature: No data available
pH: 11,5 at 100 g/l at 20 °C

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 101 mPa.s at 20 °C
Water solubility: completely miscible
Partition coefficient: n-octanol/water: log Pow: -1,08
Vapor pressure: 0,01 hPa at 20 °C
Density: 1,038 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Dissociation constant: 8,52 at 25 °C
Relative vapor density: 4,11 - (Air = 1.0)
Distillation Range: 240oC – 260oC
Water Content: 0.5 % Max by wt
Specific gravity at 20/20o C: 1.038 - 1.044
Colour 50 APHA max
Freezing Point : -21oC
Refractive Index, n20D: 1.4694
Dynamic Viscosity, at 20oC, m Pas : 101
pH of 0.1N Aq.soln. : > 10
Melting Point: -21°C
Color: Colorless to Yellow
Density: 1.0380 g/mL
Boiling Point: 243°C
Flash Point: 138°C

Infrared Spectrum: Authentic
Assay Percent Range: 99% min. (GC)
Packaging: Glass bottle
Linear Formula: (HOCH2CH2)2NCH3
Refractive Index: 1.4675 to 1.4695
Beilstein: 04, 284
Specific Gravity: 1.038
Solubility Information:
Solubility aq. soln.: miscible.
Other solubilities: miscible with benzene,soluble in most organic solvents
(alcohol,esters,aceton and chlorinated hydrocarbons),soluble in diethylether and aliphatic hydrocarbons.
IUPAC Name: 2-[(2-hydroxyethyl)(methyl)amino]ethan-1-ol
Viscosity: 101 mPa.s (20°C)
Formula Weight: 119.16
Percent Purity: 99+%
Physical Form: Liquid
Chemical Name or Material: N-Methyldiethanolamine, 99+%
Melting point: -21 °C
Boiling point: 246-248 °C(lit.)
Density: 1.038 g/mL at 25 °C(lit.)
vapor density: 4 (vs air)
vapor pressure: 0.01 mm Hg ( 20 °C)
refractive index: n20/D 1.469(lit.)

Flash point: 260 °F
storage temp.: Store below +30°C.
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 14.41±0.10(Predicted)
form: Liquid
color: Clear colorless to light yellow
Odor: Ammonical
PH Range: 11.5 at 100 g/l at 20 °C
PH: 11.5 (100g/l, H2O, 20℃)
explosive limit: 0.9-8.4%(V)
Viscosity: 99.05mm2/s
Water Solubility: MISCIBLE
BRN: 1734441
Stability: Stable.
InChIKey: CRVGTESFCCXCTH-UHFFFAOYSA-N
LogP: -1.16 at 23℃
Chemical name (CAS): 2,2'-(methylimino)bisethanol
CAS number: 105-59-9
Structural formula:
H3C−N
CH2CH2OH
CH2CH2OH

Molecular formula: C5H13NO2
Molecular weight: 119.16
Density: 1.038–1.041 g/cm3 at 20°C
Boiling point: 247°C
Vapour pressure: 2.6 hPa at 40°C
Solubility: miscible with water, low molecular weight
alcohols, esters, acetone, benzene and
chlorinated hydrocarbons; not miscible
with diethylether or aliphatic hydrocarbons
Color: yellow, Clear, Colorless
Density: 1.04 g/cm3 @ 20 °C (68 °F)
Dynamic Viscosity: 34.78 mPa.s @ 40 °C (104 °F)
Flash Point: 116 °C (241 °F)
Kinematic Viscosity: 99.05 mm2/s @ 20 °C (68 °F)
Lower Explosion Limit: 0.9 %(V)
Melting Point: -21 °C (-6 °F)
Odor: ammoniacal, amine-like
Partition Coefficient:
Pow: 25 °C (77 °F) log Pow: -1.08 @ 25 °C (77 °F)
pH: 10.4 - 11.5 @ 20 - 25 °C (68 - 77 °F)
Relative Density: 1.041 @ 20 °C (68 °F) Reference Material: (water = 1)
Relative Vapor Density: 4 @ 20 - 25 °C (68 - 77 °F)

Solubility in Water: completely miscible
Upper Explosion Limit: 10 %(V)
Vapor Pressure: < 0.01 mmHg @ 20 °C (68 °F)
Molecular Formula: C5H13NO2
Molar Mass: 119.16
Density: 1.038g/mLat 25°C(lit.)
Melting Point: -21 °C
Boling Point: 246-248°C(lit.)
Flash Point: 260°F
Water Solubility: MISCIBLE
Vapor Presure: 0.01 mm Hg ( 20 °C)
Vapor Density: 4 (vs air)
Appearance: Liquid
Color: Clear colorless to light yellow
Odor: Ammonical
BRN: 1734441
pKa: 14.41±0.10(Predicted)
PH: 11.5 (100g/l, H2O, 20℃)
Storage Condition: Store below +30°C.
Stability: Stable.
Explosive Limit: 0.9-8.4%(V)
Refractive Index: n20/D 1.469(lit.)

ΔfG°: -171.64 kJ/mol
ΔfH°gas: -383.46 kJ/mol
ΔfusH°: 19.90 kJ/mol
ΔvapH°: 62.12 kJ/mol
log10WS: 0.99
logPoct/wat: -1.097
McVol: 103.030 ml/mol
Pc: 4160.00 kPa
Tboil: [520.20; 520.45]K
Tc: 667.49K
Tfus: [250.00; 252.15]K
Vc: 0.371 m3/kmol
Cp,gas [244.80; 289.41]: J/mol×K [510.60; 667.49]
Cp,liquid [273.00; 304.00]: J/mol×K [303.15; 353.15]
η [0.0041200; 0.1420200]: Pa×s [288.00; 373.15]
ΔvapH [71.50; 73.00]: kJ/mol [422.00; 455.00]
Pvap [2.48; 101.30]: kPa [409.69; 520.28]
n0: [1.46008; 1.46840] [293.15; 303.10]
ρl [936.81; 1048.00]: kg/m3 [283.15; 423.15]
csound,fluid [1490.40; 1598.80]: m/s [288.15; 323.15]
γ [0.04; 0.04]: N/m [288.15; 333.15]



FIRST AID MEASURES of METHYLDIETHANOLAMINE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of METHYLDIETHANOLAMINE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of METHYLDIETHANOLAMINE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of METHYLDIETHANOLAMINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 60 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A (acc. to DIN 3181) for vapours of organic compounds.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of METHYLDIETHANOLAMINE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.



STABILITY and REACTIVITY of METHYLDIETHANOLAMINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available



SYNONYMS:
N-METHYLDIETHANOLAMINE
105-59-9
Methyldiethanolamine
Bis(hydroxyethyl)methylamine
2,2'-(Methylimino)diethanol
Methyl diethanolamine
Ethanol, 2,2'-(methylimino)bis-
N-Methylaminodiglycol
N-Methyliminodiethanol
591248-66-7
N-Methyl-2,2'-iminodiethanol
2,2'-Methyliminodiethanol
N-Methyldiethanolimine
2-[2-hydroxyethyl(methyl)amino]ethanol
USAF DO-52
N,N-Bis(2-hydroxyethyl)methylamine
Bis(2-hydroxyethyl)methylamine
Methylbis(2-hydroxyethyl)amine
Diethanolmethylamine
Methyliminodiethanol
Ethanol, 2,2'-(methylimino)di-
N-methyl diethanolamine
N,N-Di(2-hydroxyethyl)-N-methylamine
Bis(2-hydroxyethyl) methyl amine
NSC 11690
CCRIS 4843
2-(N-2-Hydroxyethyl-N-methylamino)ethanol
EINECS 203-312-7
BRN 1734441
UNII-3IG3K131QJ
3IG3K131QJ
N-Methylimino-2,2'-diethanol
DTXSID8025591
2-[(2-hydroxyethyl)(methyl)amino]ethan-1-ol
HSDB 6804
NSC-11690
EC 203-312-7
4-04-00-01517 (Beilstein Handbook Reference)
Ethanol,2'-(methylimino)di-
Ethanol,2'-(methylimino)bis-
WLN: Q2N1 & 2Q
N-methyl-diethanolamine
Mdea (diol)
N-Methyldethanolamne
methyl diethanol amine
MDE (CHRIS Code)
n-methyl-diethanol amine
N-methyl diethanol-amine
AMINO ALCOHOL MDA
di(hydroxyethyl)methylamine
SCHEMBL17605
bis-(Hydroxyethyl)methylamine
N-Methyl-2,2-iminodiethanol
N-Methyldiethanolamine, 99%
DTXCID605591
METHYLDIETHANOLAMINE, N-
CHEMBL3185149
N-Methyldiethanolamine, >=99%
2,2'-(methylazanediyl)diethanol
Etanol, 2,2'-(metilimino) bis-
NSC11690
NSC49131
NSC51500
METHYL DIETHANOLAMINE [INCI]
Tox21_201199
LS-389
MFCD00002848
N-METHYLDIETHANOLAMINE [HSDB]
NSC-49131
NSC-51500
STL281951
N-(2-Hydroxyethyl)-N-methylethanolam
AKOS009031354
N,N-bis-(2-hydroxyethyl)-methylamine
n-methyl-n,n-bis(2-hydroxyethyl)amine
AT34020
2,2'-(METHYLIMINO)BIS(ETHANOL)
NCGC00248955-01
NCGC00258751-01
CAS-105-59-9
2-[(2-hydroxy-ethyl)methyl-amino]-ethanol
FT-0663293
M0505
2,2'-(METHYLAZANEDIYL)BIS(ETHAN-1-OL)
2-Hydroxy-1-[(2-hydroxyethyl)methylamino]-ethyl
Q252344
J-523676
N-Methyldiethanolamine 1000 microg/mL in Ammonium Hydroxide
InChI=1/C5H13NO2/c1-6(2-4-7)3-5-8/h7-8H,2-5H2,1H
2,2′-(Methylazanediyl)di(ethan-1-ol)
Bis(2-hydroxyethyl)(methyl)amine
2,2′-Methyliminodiethanol
N,N-Bis(2-hydroxyethyl)methylamine
MDEA
Ethanol, 2,2'-(methylimino)bis-
Ethanol, 2,2'-(methylimino)di-
Bis(2-hydroxyethyl)methylamine
Diethanolmethylamine
Methylbis(2-hydroxyethyl)amine
Methyliminodiethanol
N-Methyldiethanolamine
N-Methylimino-2,2'-diethanol
N-Methyliminodiethanol
N,N-Bis(2-hydroxyethyl)methylamine
2,2'-(Methylimino)diethanol
N-Methyl-2,2-iminodiethanol
N-Methyl-2,2'-iminodiethanol
USAF DO-52
2-(N-2-Hydroxyethyl-N-methylamino)ethanol
MDEA; N-Methylaminodiglycol
N-Methyldiethanolimine
Eve
MDEA (diol)
N-(2-Hydroxyethyl)-N-methylethanolam
N,N-Di(2-hydroxyethyl)-N-methylamine
NSC 11690
MDEA, N-Methyl diethanolamin
2,2’Methyliminodiethanol
N- methyl diethanolamine
Methyldiethanolamine
N,N-Bis(2-Hydroxy ethyl)methylamine
Methyldiethanolamin
MDEA
2,2'-(Methylimino)diethanol
2-(N-2-Hydroxyethyl-N-methylamino)ethanol
Bis(2-hydroxyethyl) methyl amine
Bis(2-hydroxyethyl)methylamine
2,2'-Methyliminodiethanol
Ethanol, 2,2'-(methylimino)bis-
Ethanol, 2,2'-(methylimino)di-
N-Methyldiethanolamine.
MDEA; 2,2'-(Methylimino)diethanol
2-(N-2-Hydroxyethyl-N-methylamino)ethanol
Bis(2-hydroxyethyl) methyl amine
Bis(2-hydroxyethyl)methylamine
2,2'-Methyliminodiethanol
Ethanol, 2,2'-(methylimino)bis-
Ethanol, 2,2'-(methylimino)di-
N-Methyldiethanolamine.
MDEA;METHYL DIETHANOLAMINE
Methyldiethanolamin
Methyliminodiethanol
FC MDEA
usafdo-52
USAF DO-52
Mdea (diol)
Diethanolmethylamine
N-Methyldiethanolami
2,2'-(Methylimino)diethanol
2-(N-2-Hydroxyethyl-N-methylamino)ethanol
Bis(2-hydroxyethyl) methyl amine
Bis(2-hydroxyethyl)methylamine
Ethanol, 2,2'-(methylimino)bis-
MDEA
Methylbis(2-hydroxyethyl)amine
N,N-Bis(2-hydroxyethyl)methylamine
N,N-Di(2-hydroxyethyl)-N-methylamine
N-Methyl-2,2'-iminodiethanol
N-Methylaminodiglycol
N-Methyldiethanolimine; N-Methyliminodiethanol
2,2'-Methyliminodiethanol
Ethanol, 2,2'-(methylimino)bis-
Ethanol, 2,2'-(methylimino)di-
Methyl diethanolamine
2,2`-(Methylimino)bis-ethanol
Diethanolmethylamine
EVE; MDEA (diol)
Methyldiethanolamine
Methyliminodiethanol
N-(2-hydroxyethyl)-N-methylethanolamine
N-Methylbis(2-hydroxyethyl)amine
Amietol M12
Methyldiethanolamin
2,2-(Methylimino)Diethanol
2,2-Methyliminodiethanol
N-Methylediethanolamine
N-Methyl Diethanolamine
Methyl Diethanlamine
2-hydroxy-N-(2-hydroxyethyl)-N-methylethanaminium
MDEA
N,N-Bis(2-Hydroxyethyl)Methylamine
MDEA
Methyl Diethanlamine
METHYL DIETHANOLAMINE
N-METHYLDIETHANOLAMINE
N-Methyldiethanolamine
N-Methyl Diethanolamine
N-Methylediethanolamine
2,2-Methyliminodiethanol
2,2-(Methylimino)Diethanol
N-METHYL-2,2'-IMINODIETHANOL
BIS(2-HYDROXYETHYL)METHYLAMINE
N-METHYL-2,2-IMINOBIS(ETHANOL)
N,N-BIS(2-HYDROXYETHYL)METHYLAMINE
N-METHYL-N-(2-HYDROXYETHYL)-2-AMINOETHANOL
2-hydroxy-N-(2-hydroxyethyl)-N-methylethanaminium


METHYLDIGLYCOL
Chemical Characterization Diethylene glycol monomethyl ether 2-(2-Methoxyethoxy)-ethanol CAS-No.: 111-77-3 EINECS-No.: 203-906-6 Product Description Methyl diglycol is a colorless, neutral, weakly hygroscopic and liquid with a mild pleasant odor. It is miscible in any ratio with water and the usual organic solvents e.g. acetone, diethyl ether and methanol. Methyl diglycol is starting material for the production of methyl diglycol acetate. It is also used as a solvent for fats, oils and waxes; constituent of hydraulic fluids; additive in cleaners for soiled surfaces and starting material for syntheses. To prevent dermal exposure methyl diglycol is not suitable for any application in paints and paint strippers. The technical characteristics of methyl diglycol enable it to meet the requirements stipulated for the technical Supply Conditions as drawn up in accordance with MIL-DTL-85470B in addition with an antioxidant (Clariant product name: Methyl diglycol JFA). Storage Advices Glycol ethers and their derivatives tend to form peroxides in the presence of air or oxygen. For further informations please refer to the safety data sheet. Storage tanks should be made from norm-steel or stainless steel. Aluminum and other light metals are not suitable due to alcoholate formation with methyl diglycol. Azeotropic mixtures Methyl diglycol builds no azeotrope with water and diglycol; nevertheless with several other organic solvents. Some of them are listed here: Methyl diglycol (in %)-Azeotrope with-in %-b.p. (°C) (at 1013 mbar) 80-acetophenone-20-191,90 46-amylether-54-179,50 49-dimethylaniline-51-184,85 33-dipentene-67-168,50 70-glycol-30-192,00 23-isoamylether-77-168,85 13-mesitylene-87-162,50 89-naphtaline-11-192,20 52-o-cresol-48-201,50 61-phenol-39-199,65 45-phenylacetate-55-188,60 30-p-cresol-70-208,00 Technical Data METYLDIGLYCOL molar mass-g/mol-120,2 METYLDIGLYCOL solidification point (DIN 51583) °C -65 METYLDIGLYCOL boiling range/1013 hPa °C 190-196 METYLDIGLYCOL flash point(DIN 51755) °C 91 METYLDIGLYCOL ignition temperature (DIN 51794) °C 245 METYLDIGLYCOL density/20°C (DIN 51757) g/cm³ 1,018-1,022 METYLDIGLYCOL kinematic viscosity/20°C (DIN 51562) mm²/s 3,9 METYLDIGLYCOL vapor pressure/20°C mbar 0,3 METYLDIGLYCOL heat of evaporation /1013 hPa kJ/kg 396 METYLDIGLYCOL evaporation number (DIN 53170, Diethylether = 1) ca. 900 METYLDIGLYCOL refractive number nD20 (DIN 51423, part 2) 1,4263 METYLDIGLYCOL surface tension/25°C mN/m 28,5 METYLDIGLYCOL dielectric constant/20°C (DIN 53483) 15,8 METYLDIGLYCOL specific heat /20°C kJ/kgK 2,15 METYLDIGLYCOL thermal conductivity /20°C W/mK 0,18 METYLDIGLYCOL critical density g/cm3 0,322 METYLDIGLYCOL critical temperature °C 357,1 METYLDIGLYCOL critical pressure bar 35,4 METYLDIGLYCOL miscibility with water miscible
Methyldiethanolamine ( METHYL DIETHANOLAMINE)
METHYL GLUCETH-20, N° CAS : 68239-42-9 - Méthyle Gluceth-20, Origine(s) : Synthétique, Nom INCI : METHYL GLUCETH-20. Le méthyle Gluceth-20 est produit à partir de glucose, d'alcool méthylique et de dérivés de sucre. Il est utilisé en cosmétique en tant qu'émollient (adoucit la peau), humectant (retient l'eau) et hydratant. Il est employé principalement dans les soins hydratants et nourrissants pour des peaux plutôt sèches et irritées.Ses fonctions (INCI): Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau. Hydratant : Augmente la teneur en eau de la peau et aide à la maintenir douce et lisse
Méthyle Gluceth-20
METHYLENE BIS MORPHOLINE; N,N-Dimorpholinomethane; Morpholine,4,4-methylenebis-; Bis(4-morpholinyl)methane; N,N'-Methylenebismorpholine; 4,4'-methanediyldimorpholine; 4,4-methylenebis-Morpholine; N,N-Methylene-bis-morpholine cas no: 5625-90-1
METHYLENE BIS MORPHOLINE
N,N'-Methylenebisacrylamide; N-[(Prop-2-enoylamino)methyl]prop-2-enamide cas no: 110-26-9
METHYLENE BISACRYLAMIDE
N,N-Dimorpholinomethane; Morpholine,4,4-methylenebis-; Bis(4-morpholinyl)methane; N,N'-Methylenebismorpholine; 4,4'-methanediyldimorpholine; 4,4-methylenebis-Morpholine; N,N-Methylene-bis-morpholine CAS:5625-90-1
Methylene Bismorpholine
N,N-Dimorpholinomethane; Morpholine,4,4-methylenebis-; Bis(4-morpholinyl)methane; N,N'-Methylenebismorpholine; 4,4'-methanediyldimorpholine; 4,4-methylenebis-Morpholine; N,N-Methylene-bis-morpholine CAS:5625-90-1
METHYLENE CHLORIDE
Dichloromethane; Freon 30; Methylene dichloride; Chlorure De Methylene; Chlorocarbon; Methylene Bichloride; Metylenu Chlorek CAS NO:75-09-2
METHYLENE GLYCOL
Methylenephosphonic Acid; Bis Hexamethylenetriaminepenta(Methylenephosphonic Acid); TPMP; DTMPA; DETA-Phos; [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis- Phosphonic acid; CAS NO: 15827-60-8
Methylene-bis-morpholine
N,N'-Methylene-bis-morpholine helps to increase the life of metalworking fluid with maintaining the stable product function and preserving the fluid from bacteria and fungi. It could be for metalworking fluid concentrate during manufacturing or for tank side treatment. Name: N,N'-Methylene-bis-morpholine CAS: 5625-90-1 N,N'-Methylene-bis-morpholine - CAS 5625-90-1 Molecular Formula: C9H18N2O2 Molecular Weight: 186.251 Name N,N'-Methylene-bis-morpholine Synonyms N,N-Dimorpholinomethane Morpholine,4,4-methylenebis- Bis(4-morpholinyl)methane N,N'-Methylenebismorpholine 4,4'-methanediyldimorpholine 4,4-methylenebis-Morpholine CAS 5625-90-1 EINECS 227-062-3 N,N'-Methylene-bis-morpholine - Physico-chemical Properties Molecular Formula C9H18N2O2 Molar Mass 186.251 g/mol Density 1.09g/cm3 Boling Point 265.1°C at 760 mmHg Flash Point 77.6°C Vapor Presure 0.00935mmHg at 25°C Refractive Index 1.496 1.Product name:N,N'-Methylene-bis-morpholine 2.Molecular weight:186.25 Molecular formula:C9H18N2O2 3.CAS No:5625-90-1 Eiencs No:227-062-3 4.Specification Item Index Purity of Active Content >92% Appearance Colorless liquid Density 1.08-1.10g/m³ Boiling point ℃ 122-124(P=12torr) PH(1% water) 9.0-11.0 Solubility in Water Completely Usage of MBM ( Methylene-bis-morpholine) : 1, a low toxicity broad spectrum fungicide for water-based metalworking fluid 2, anti-Bacteria and fungi effectively 3, fully meet with the requirements of water-based metalworking fluid: low skin irritation, mild odor, low toxicity; formulation compatibility, lasting bactericidal. At higher concentrations, fungi and molds also have better inhibition.Recommended addition amount (mass ratio): Recipe 2-3%, the working liquid 1-2‰; 6.Package: 25kg/ drums or 200kg/ drums Application and Benefits of Methylene-bis-morpholine : Biocide ( Preservative ) in the the metal working fluid composition permits the efficient practice of cutting, grinding, form rolling, press working and plastic working of metallic materials. In addition, the fluid composition is excellent in the antiseptic properties and it is seldom that the fluid composition adversely affects the environment of the earth and the human bodies. The fluid composition comprises a morpholine compound,the fluid composition is significantly improved in the antiseptic properties and the service life of the metal working fluid composition can thus significantly be extended, as compared with conventionally known metal working fluid compositions. As a result, the fluid composition would permit the saving of natural resources, and the reduction of the amount of waste matter (waste fluid) and accordingly, the use thereof would result in the reduction of any adverse effect on the environment of the earth. NO MORE FORMALDEHYDE !! Formaldehyde occurs naturally in the environment as a by-product of metabolic processes in humans, animals and through the natural decay process of plant species. Formaldehyde is even detectable in human breath at low levels. Under the changes planned to the labelling of certain chemicals, formalin-releasing species have been re-classified according to their total potential to release formaldehyde and not through actual measurement in use. Research by several chemical manufacturers supports very low levels, no higher than the surrounding environment, when used well managed metalworking fluid systems. Formaldehyde has long been classed as a category 1B carcinogen. Formaldehyde Depots or ‘donors’ (FADs) have been used to improve the sump life of soluble metalworking fluids. New legislation now affects certain formalin- containing biocides. Under the recent update to CLP regulation, ATP (Adaptation to Technical Progress, review May 4th 2017), any product or treated article which contains certain formalin-containing biocides (to protect the function of the product) will need to be labelled as category 1B. Examples of the biocides affected include methylene bis-morpholine (MBM) and methylene bis[5-methyloxazolidine] (MBO). Methylene bis-morpholine (MBM) is a low toxicity biocide developed for use in metal working concentrates. Nipacide MBM is effective against a wide range of microorganisms including gram positive and gram negative bacteria, yeast and fungi. Microorganisms grow at a rapid rate and without use of the correct biocide, numbers can increase dramatically. Methylene bis-morpholine (MBM)is recommended for preservation of metal working solution concentrates. N,N'-Methylene-bis-morpholine is effective against a wide range of spoilage organisms and effective over a wide pH and temperature range. Use level; Methylene bis morpholine should be evaluated in finished products at levels between 2.0% and 5.0%.
Méthyléther d'hydroquinone/Mequinol
Trisodium dicarboxymethyl alaninate; * N,N-Bis(carboxymethyl)-DL-alanin trisodium salt; N-(1-Carboxyethyl)-iminodiacetic acid; α-Alanindiacetic acid; α-ADA; MGDA-Na3; Trilon M; carboxylatoethyl)iminodiacetate, methylglycinediacetic acid trisodium salt (MGDA-Na3) or trisodium α-DL-alanine diacetate (α-ADA), cas no: 164462-16-2
METHYLGLUCOSE DIOLEATE

Methylglucose dioleate is a versatile cosmetic ingredient derived from natural sources.
Its polyethylene glycol ether composition makes it effective as a surfactant in various cosmetic products.
Methylglucose dioleate acts as a potent thickener, adding a luxurious texture to skincare formulations.
Emulsifying properties enable it to create stable and visually appealing cosmetic emulsions.



APPLICATIONS


Some applications of Methylglucose dioleate include:

Surfactant:
Methylglucose dioleate acts as a surfactant, enabling it to reduce the surface tension between different substances.
Methylglucose dioleate helps in mixing oil and water-based ingredients, creating stable and uniform cosmetic formulations.

Thickener:
Methylglucose dioleate functions as a thickening agent in various cosmetic products, such as creams, lotions, and gels.
Methylglucose dioleate imparts a luxurious and smooth texture to the products, enhancing their application and skin feel.

Emulsifier:
Methylglucose dioleate is an effective emulsifier, allowing the formation of stable oil-in-water emulsions.
This property is particularly valuable in creating emulsified skincare products like creams and lotions.

Skin Irritation Reduction:
Due to its gentle and non-irritating nature, cosmetics containing Methylglucose dioleate can be used in formulations targeted for sensitive skin or products designed to minimize skin irritation.

Moisturizer:
Methylglucose dioleate's ability to form a protective barrier on the skin's surface helps retain moisture, making it a suitable ingredient for moisturizing products.

Eco-friendly and Natural Cosmetics:
Methylglucose dioleate's derivation from natural Methylglucose and Oleic Acid aligns with the growing demand for eco-friendly and naturally derived cosmetic ingredients.

Hypoallergenic Formulations:
Its low potential for causing skin irritation makes it a favored choice in hypoallergenic cosmetic formulations.

Baby Care Products:
Methylglucose dioleate's gentle and non-irritating properties make it a suitable ingredient in baby care products like lotions and creams.

Haircare Products:
Methylglucose dioleate can be used in haircare products to provide conditioning and moisturizing effects, maintaining a balanced moisture level in the hair.

Clean Beauty Standards:
Methylglucose dioleate's natural origin and safe profile align with the principles of clean beauty, appealing to consumers seeking safer and more natural cosmetic options.

Sunscreens:
Methylglucose dioleate can be included in sunscreen formulations to enhance their texture and provide moisturizing benefits.

Makeup Products:
Methylglucose dioleate can be found in various makeup products, such as foundations and concealers, to improve their spreadability and skin feel.

Pharmaceutical Formulations:
Given its non-irritating and skin-friendly nature, Methylglucose dioleate might find applications in pharmaceutical formulations, such as topical creams or ointments.

Drug Delivery Systems:
Its emulsifying properties could potentially be utilized in the development of drug delivery systems, allowing for controlled and targeted release of active pharmaceutical ingredients.

Food Industry:
As an emulsifier and thickener, Methylglucose dioleate could be explored for use in food products, enhancing texture and stability in certain formulations.

Agrochemicals:
The surfactant properties of the compound might have applications in the formulation of agrochemicals, such as herbicides or insecticides.

Industrial Applications:
Methylglucose dioleate could be considered for various industrial applications, such as in lubricants or metalworking fluids due to its emulsification and stabilizing abilities.

Cleaning Products:
Its surfactant properties may make it suitable for use in household or industrial cleaning products to enhance their cleaning efficiency.

Textile Industry:
As a thickener and emulsifier, it could potentially be used in textile applications, such as fabric softeners or specialty finishes.

Paints and Coatings:
Its emulsifying properties might find applications in water-based paints and coatings.


Methylglucose dioleate is widely utilized as a surfactant in various cosmetic formulations, such as cleansers and shampoos.
Its excellent emulsifying properties make it a key ingredient in the production of stable creams and lotions.
Methylglucose dioleate's thickening ability adds a luxurious texture to moisturizers and body butters.

Due to its gentle nature, Methylglucose dioleate is often incorporated into products intended for sensitive and delicate skin, like baby lotions.
Methylglucose dioleate acts as a co-emulsifier in sunscreens, aiding in the uniform distribution of UV filters and enhancing their water-resistance.

In haircare products like conditioners, it helps in detangling and providing smoothness to the hair.
Methylglucose dioleate is used as an emulsifier in foundation formulations, allowing even dispersion of pigments for a smooth application.

Methylglucose dioleate contributes to the creamy texture of lipsticks and lip balms.
Its emulsifying properties extend to body washes and shower gels, creating stable and visually appealing formulations.

As an essential ingredient in bath oils, Methylglucose dioleate ensures the even dispersion of oils in water, enhancing the bathing experience.
Methylglucose dioleate is incorporated into hand creams and moisturizing gloves for its skin-soothing benefits.
Methylglucose dioleate is utilized in facial masks to stabilize the mixture and promote even application on the skin.

Methylglucose dioleate's thickening properties are utilized in hair styling products like gels and mousses.
Methylglucose dioleate acts as an effective emulsifier in makeup removers, enabling the removal of stubborn cosmetics.
Methylglucose dioleate can be found in anti-aging skincare products, helping to disperse active ingredients that promote skin elasticity and hydration.
Methylglucose dioleate's emulsification capabilities are harnessed in body scrubs and exfoliants, combining oil and exfoliating particles.
In baby wipes, Methylglucose dioleate plays a role in evenly distributing cleansing agents while maintaining gentleness.

Methylglucose dioleate can be used in sunless tanning products to ensure an even application of the tanning agent.
Methylglucose dioleate finds application in massage oils, providing a smooth glide and preventing greasiness.
Methylglucose dioleate is employed in moisturizing face masks, improving the product's consistency and hydration benefits.

In post-shave lotions, Methylglucose dioleate aids in soothing the skin while keeping the formulation stable.
Methylglucose dioleate's thickening properties extend to body creams and body soufflés.
Methylglucose dioleate is included in cosmetic serums to enhance the absorption of active ingredients into the skin.

Methylglucose dioleate can be used in waterproof makeup products, ensuring their long-lasting properties.
Methylglucose dioleate's emulsifying capabilities make it useful in natural and organic cosmetic products, adhering to clean beauty principles.



DESCRIPTION


Methylglucose dioleate is a versatile cosmetic ingredient derived from natural sources.
Its polyethylene glycol ether composition makes it effective as a surfactant in various cosmetic products.
Methylglucose dioleate acts as a potent thickener, adding a luxurious texture to skincare formulations.
Emulsifying properties enable it to create stable and visually appealing cosmetic emulsions.

Methylglucose dioleate's gentle nature reduces irritation, making it suitable for sensitive skin types.
Cosmetics featuring this compound provide a soothing and comfortable experience to users.
Its unique molecular structure gives it a high molecular weight, preventing deep skin penetration.

As a result, Methylglucose dioleate forms a protective barrier on the skin's surface, locking in moisture.
Methylglucose dioleate enhances the overall stability and shelf life of cosmetic products.

Methylglucose dioleate imparts a smooth and velvety feel to cosmetic formulations, leaving the skin soft and supple.
Due to its non-greasy nature, Methylglucose dioleate is well-suited for a wide range of skincare and haircare products.
Methylglucose dioleate is known for its compatibility with various active ingredients in cosmetic formulations.

Its eco-friendly and sustainable origin aligns with the growing demand for natural cosmetics.
Cosmetics containing this compound are favored for their mildness and non-comedogenic properties.

Methylglucose dioleate plays a vital role in creating well-balanced and stable oil-in-water emulsions.
The compound's excellent dispersing ability ensures even distribution of ingredients in cosmetic products.
Its low potential for skin irritation makes it a popular choice in hypoallergenic formulations.
Methylglucose dioleate's viscosity-enhancing capabilities lend a luxurious feel to creams and lotions.

Methylglucose dioleate contributes to the elegant appearance and texture of cosmetic products during application.
As an effective emollient, Methylglucose dioleate leaves the skin feeling moisturized and conditioned.
Methylglucose dioleate's natural origin and safe profile align with clean beauty standards.

Methylglucose dioleate is a preferred ingredient in baby care products for its gentle and soothing properties.
When used in haircare products, Methylglucose dioleate aids in maintaining a balanced moisture level in the hair.
The surfactant properties allow Methylglucose dioleate to create gentle yet effective cleansing products.
Methylglucose dioleate exemplifies the innovation in cosmetic science, catering to consumers seeking effective yet skin-friendly formulations.



FIRST AID


Skin Exposure:

Remove contaminated clothing and accessories immediately.
Wash the affected skin area gently but thoroughly with plenty of soap and water.
Rinse the skin with water for at least 15 minutes to ensure complete removal of the chemical.
If skin irritation, redness, or other adverse reactions occur, seek medical attention promptly.
Avoid using any chemical solvents or substances to remove the chemical from the skin, as they may exacerbate the situation.


Eye Exposure:

Flush the affected eye(s) with clean water or saline solution immediately. Use an eye wash station if available.
Hold the eye open while flushing to ensure thorough rinsing of the eye surface.
Continue flushing the eye(s) for at least 15 minutes or until medical help arrives.
Do not rub or put pressure on the eyes as it may worsen any potential damage.
Seek immediate medical attention or contact an ophthalmologist if eye irritation, pain, or vision problems persist.


Inhalation:

If there is accidental inhalation of any unknown substance or chemical, immediately move to an area with fresh air.
If the person exposed to the chemical is experiencing difficulty breathing or any respiratory distress, seek immediate medical attention or call emergency services.


Ingestion:

If the substance is ingested accidentally, do not induce vomiting unless directed to do so by a healthcare professional or poison control center.
Rinse the mouth thoroughly with water if the chemical was swallowed accidentally.
Seek immediate medical attention or contact a poison control center for further guidance.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including safety goggles, chemical-resistant gloves, lab coat or protective clothing, and closed-toe shoes when handling any chemicals.

Ventilation:
Work in a well-ventilated area or use fume hoods or local exhaust ventilation systems to minimize exposure to chemical vapors and fumes.

Avoid Direct Contact:
Avoid direct skin contact with the chemical.
If contact occurs, promptly wash the affected area with soap and water.

Mixing and Dilution:
Follow specific instructions for mixing or diluting the chemical.
Always add chemicals to water slowly, not the other way around, to prevent splashes or releases of energy.

Labeling:
Keep containers properly labeled with the correct chemical name, concentration, hazard symbols, and any other relevant information.

Containment:
Use appropriate containers and storage units to prevent spills and leaks.
Secondary containment measures may be necessary for hazardous materials.

Transfer with Care:
Use appropriate tools and equipment to transfer the chemical safely.
Avoid transferring chemicals by mouth or using equipment not meant for that purpose.

No Eating, Drinking, or Smoking:
Prohibit eating, drinking, or smoking in areas where chemicals are handled to avoid accidental ingestion.


Storage:

Compatibility:
Store chemicals based on compatibility to prevent any undesirable reactions or hazards.
Segregate incompatible substances.

Temperature:
Store chemicals at the recommended temperature range specified in the SDS or as indicated by the supplier.

Light Exposure:
Some chemicals may be light-sensitive.
Store light-sensitive substances in opaque containers or away from direct light.

Moisture:
Protect chemicals from moisture by keeping containers tightly sealed and stored in dry conditions.

Secure Storage:
Store chemicals in a dedicated chemical storage area with limited access to authorized personnel only.

Ventilation:
Ensure the storage area is well-ventilated to prevent the buildup of vapors or fumes.

Shelving and Stability:
Use appropriate shelving and ensure that chemicals are stable and not at risk of falling or collapsing.

Emergency Equipment:
Keep emergency response equipment, such as spill kits and eyewash stations, readily available in the storage area.

Separate from Food and Pharmaceuticals:
Store chemicals separately from food, beverages, pharmaceuticals, and other items not intended for chemical use.



SYNONYMS


Methyl Glucose Oleate Ether
Polyethylene Glycol Ether of Methylglucose Oleate
Methyl Glucose Dioleoyl Ether
Methyl Glucose Oleate Diether
PEG Ether of Methylglucose Oleate
Methyl Glucose Oleate Diester Polyethylene Glycol Ether
Methylglucose Oleate PEG Diester
Methylglucose Oleic Acid Diester PEG Ether
Methylglucose Dioleic Acid Polyethylene Glycol Ether
Methylglucose Dioléate d'Oleic Acid
Oleic Acid Methyl Glucose Diester Ethoxylate
Methyl Glucose Di-Oleate Ethylene Glycol Ether
Oleoyl Methyl Glucose Ether
Methyl Glucose Dioléate PEG Esters
Methyl Glucose Oleyl Ether
Ethoxylated Methyl Glucose Oleate
Methyl Glucose Oleic Acid Ester PEG Ether
Polyethylene Glycol Ether of Methylglucose Dioléate
Methyl Glucose Dioleate Ethoxylate
Methyl Glucose Oleate PEG Diether
Ethylene Glycol Ether of Methylglucose Dioleate
Oleic Acid Methyl Glucose Diol Ether
Methyl Glucose Oleic Acid Diester Ethoxylate
Methyl Glucose Oleic Acid PEG Ester
Methyl Glucose Oleyl Alcohol Diester PEG Ether
Oleic Acid Methyl Glucose Polyethylene Glycol Ether
Methyl Glucose Oleoyl Polyethylene Glycol Ether
Methyl Glucose Oleate Diol PEG Ether
Ethylene Glycol Methyl Glucose Dioléate
Methyl Glucose Oleyl Diester Ethoxylate
Methyl Glucose Dioleate Ethylene Glycol Ester
Oleic Acid Methyl Glucose Oleyl Ether
Methyl Glucose Oleate Diol Polyethylene Glycol Ether
Methylglucose Oleic Acid Diol Ether PEG
Methyl Glucose Dioléate Oleic Acid Ethoxylate
Oleic Acid Methyl Glucose PEG Diether
Ethylene Glycol Ether of Methyl Glucose Oleate
Methyl Glucose Oleyl Polyethylene Glycol Diether
Methyl Glucose Oleic Acid Diester Ethylene Glycol Ether
Methyl Glucose Dioleyl Polyethylene Glycol Ether
Ethoxylated Methyl Glucose Oleic Acid Ester
Methyl Glucose Oleate Ethoxylate Diol
Oleic Acid Methyl Glucose Diether Ethylene Glycol
Methyl Glucose Oleyl Acid Diol PEG Ether
Methyl Glucose Oleic Acid Polyethylene Glycol Diether
Ethylene Glycol Ether of Methyl Glucose Dioleate
Methyl Glucose Oleate Ethoxylated Diol
Methyl Glucose Oleic Acid Diester PEG Esters
Methyl Glucose Dioleic Acid Polyethylene Glycol Ester
Oleic Acid Methyl Glucose Diol Ether PEG
Methyl Glucose Oleate PEG Dioléate
Methyl Glucose Oleyl Diester Ethylene Glycol Ether
Ethylene Glycol Methyl Glucose Oleate Diester
Methyl Glucose Oleic Acid Ethoxylated Diol
Methyl Glucose Dioleate Ethoxylated Oleic Acid
Methyl Glucose Oleic Acid Diol PEG Ether
Oleic Acid Methyl Glucose Diol Polyethylene Glycol Ester

METHYLGLYCINEDIACETIC ACID 
Synonyms: D,L-methylglycinediacetic acid trisodium salt; Trisodium 2-Methylnitrilotriacetate Hydrate; methylglycine-N,N-diacetic CAS No.: 164462-16-2
Methylglycine N,N-diacetic acid, Trisodium Salt
N° CAS : 99-76-3 ; 4-Hydroxybenzoate de méthyle, Autre langue : Metilparabeno, Nom INCI : METHYLPARABEN. Methyl-paraben ,CAS : 99-76-3.Synonymes : 4-(Methoxycarbonyl)phenol;4-Hydroxybenzoic acid methyl ester;Abiol;Aseptoform;Benzoic acid, 4-hydroxy-, methyl ester;Benzoic acid, p-hydroxy-, methyl ester;Maseptol;Metaben;Methyl 4-hydroxybenzoate;Methyl chemosept;Methyl ester of p-hydroxybenzoic acid;Methyl p-hydroxybenzoate;Methyl p-oxybenzoate;Methyl parahydroxybenzoate;Methyl parasept;Methylben;Methylester kyseliny p-hydroxybenzoove;Methylester kyseliny p-hydroxybenzoove (Czech);Metoxyde;Moldex, Nipagin, Nipagin M, p-(methoxycarbonyl)phenol, p-Carbomethoxyphenol, p-Hydroxybenzoic acid methyl ester, p-Hydroxybenzoic methyl ester, p-Oxybenzoesauremethylester, p-Oxybenzoesauremethylester (German), Paridol, Preserval M,Septos, Solbrol, Solbrol M,Tegosept M, Nom chimique : Methyl 4-hydroxybenzoate. N° EINECS/ELINCS : 202-785-7. Additif alimentaire : E218. Noms français : 4-(METHOXYCARBONYL)PHENOL; 4-HYDROXYBENOZIC ACID METHYL ESTER; Ester méthylique de l'acide hydroxy-4 benzoïque; HYDROXY-4 BENZOATE DE METHYLE; METHYL 4-HYDROXYBENZOATE; METHYL ESTER OF P-HYDROXYBENZOIC ACID METHYL P-HYDROXYBENZOATE; METHYL PARA-HYDROXYBENZOATE; METHYL PARAHYDROXYBENZOATE; P-CARBOMETHOXYPHENOL;P-HYDROXYBENZOATE DE METHYLE P-HYDROXYBENZOIC ACID METHYL ESTER; P-METHOXYCARBONYLPHENOL. Utilisation et sources d'émission: Agent antiseptique
METHYLGLYCOL
Chemical Characterization Ethylene glycol monomethylether 1-Hydroxy-2-methoxyethane 2-Methoxyethanol CAS-No.: 109-86-4 EINECS-No.: 203-713-7 Registrations: EINECS (Europe), TSCA (USA), AICS (Australian),DSL (Canada), ECL (Korea), PICCS (Philippines), ENCS (Japan),ASIA-PAC Product Description Methyl glycol is a colorless, neutral, weakly liquid with a mild pleasant odor. It is miscible in any ratio with water and the usual organic solvents (except for saturated hydrocarbons, e. g. special boiling point petroleum spirits).Methyl glycol enters into the typical alcohol reactions like esterification, etherification, oxidation, acetal and alcoholate formation. Therefore it is used as a starting material for syntheses of organic intermediates. Methyl glycol is also used as an antifreeze in aviation fuels for jet aircrafts (about 0.10 - 0.15 % by volume, relative to the fuel). The technical characteristics of methyl glycol enable it to meet the requirements stipulated for the technical Supply Conditions as drawn up in accordance with MIL-DTL-2786G (NATO-Code-Number: S-748) in addition with an antioxidant. Storage Advices Glycol ethers and their derivatives tend to form peroxides in the presence of air or oxygen. To prevent the formation of peroxides the product should be stored under an inert nitrogen atmosphere. Despite the very mild odor of methyl glycol, the general precautionary measures for the handling of solvents must always be observed. For further informations please refer to the safety datasheet. Storage tanks should be made from norm-steel or stainless steel. Aluminium and other light metals are not suitable due to alcoholate formation with methyl glycol. We found the following materials suitable. Technical Data Methyl glycol molar mass g/mol 76,1 Methyl glycol solidification point (DIN 51583) °C -85 Methyl glycol boiling range/1013 hPa °C 123-126 Methyl glycol flash point(DIN 51755) °C 37 Methyl glycol ignition temperature (DIN 51794) °C 325 Methyl glycol density/20°C (DIN 51757) g/cm³ 0,967 Methyl glycol vapor density (Luft = 1) 2,63 Methyl glycol vapor pressure/20°C mbar 8,1 Methyl glycol kinematic viscosity/20°C (DIN 51562) mm²/s 1,71 Methyl glycol dielectric constant/20°C (DIN 53483) 16,9 Methyl glycol critical density g/cm3 0,313 Methyl glycol critical temperature °C 292,2 Methyl glycol critical pressure bar 50,1 Methyl glycol dipole moment/25°C Debye 2,04 Methyl glycol surface tension/25°C mN/m 31,2 Methyl glycol refractive number nD20 (DIN 51423, part 2) 1,402 Methyl glycol heat of evaporation /1013 hPa kJ/kg 519 Methyl glycol evaporation number (DIN 53170, Diethylether = 1) 34 Methyl glycol thermal conductivity /20°C W/mK 0,19 Methyl glycol specific heat /20°C kJ/kg*K 2,30
Methylguanidoacetic acid
Methylguanidoacetic acid; Glycocyamine; 2-Guanidinoacetic acid cas no: 6020-87-7
METHYLHYDROXYETHYL CELLULOSE
Methylhydroxyethyl cellulose, also known as Hydroxyethyl Methyl Cellulose (HEMC)e, is a non-ionic cellulose ether.
Methylhydroxyethyl cellulose is made from natural polymer cellulose through a series of etherification reactions.
Methylhydroxyethyl cellulose is a white, powder.


CAS Number: 9032-42-2
Chem/IUPAC Name: Cellulose methyl ether, 2-hydroxyethyl ether
Chemical formula: variable


Methylhydroxyethyl cellulose is made from highly pure cotton-cellulose by reaction of etherification under alkaline conditions without any organs of animals, fat and other bioactive constituents.
Methylhydroxyethyl cellulose’s a cellulose ether which is based on methyl cellulose.


Compared to other cellulose ether chemistries, the methylcellulose derivatives have a slightly more Newtonian flow characteristic which provides increased high-shear (ICI) viscosity.
Methylhydroxyethyl cellulose has a good stability even though in alkaline environment and provide a good stability in heat environment.


Methylhydroxyethyl cellulose provides viscosity, which can be used as an anti – precipitation agent.
Methylhydroxyethyl cellulose may contain further additives which for example control the dissolution behavior or the thickening power.
Methyl Hydroxyethyl Cellulose (MHEC), in the form of a powder, is a thickening agent.


Methylhydroxyethyl cellulose is more resistant to saline, easily soluble in water and has higher gel temperature. Methylhydroxyethyl cellulose is also known as HEMC, Methyl Hydroxyethyl Cellulose, which can be used as highly efficient water retention agent, stabilizer, adhesives and film-forming agent in construct.


Methylhydroxyethyl cellulose is a modified hydroxyethyl methylcellulose with delayed solubility.
Methylhydroxyethyl cellulose is also called as Hydroxyethyl Methyl Cellulose HEMC.
Methylhydroxyethyl cellulose is a non-ionic cellulose ether made from natural high polymer cellulose.


The properties of Methylhydroxyethyl cellulose and methylcellulose are similar, but the presence of hydroxyethyl makes Methylhydroxyethyl cellulose cellulose more soluble in water, the solution is more compatible with salt and has a higher aggregation temperature.
Methylhydroxyethyl cellulose is also called hypromellose.


Methylhydroxyethyl cellulose is a white, yellow-white or off-white powder or granules, hygroscopic after drying.
Methylhydroxyethyl cellulose is a methylcellulose based cellulose.
Methylhydroxyethyl cellulose's pH value exists between 5.0 and 8.0.


Methylhydroxyethyl cellulose is water soluble nonionic cellulose ethers, which are offered as free flowing powder or in granular form cellulose.
Methylhydroxyethyl cellulose is considered to be non-toxic.
Methylhydroxyethyl cellulose can be described as a modified cellulose polymer consisting of methyl, ethyl, and hydroxyethyl side chains.


Methylhydroxyethyl cellulose is a kind of methyl cellulose derivative which is made from natural high polymer cellulose.
Methylhydroxyethyl cellulose excels in water retention and improves adhesion.
Methylhydroxyethyl cellulose dissolves in hot and cold water, forms a transparent viscous solution and is insoluble in common organic solvents.


Methylhydroxyethyl cellulose is a white, odorless powder.
Methylhydroxyethyl cellulose is a water soluble.
Methylhydroxyethyl cellulose is featured by hygroscopicity and hardly soluble in hot water, acetone, ethanol and toluene.


Methylhydroxyethyl cellulose is a non-ionic cellulose ether made from natural high polymer cellulose.
Methylhydroxyethyl cellulose is an odourless, tasteless and non-toxic white powder, which can be dissolved in cold water to form a transparent viscous solution.


Methylhydroxyethyl cellulose is a kind of odorless, tasteless, non-toxic white powder or granule.
Methylhydroxyethyl cellulose offers many of the same advantages as other methyl cellulose derivatives, such as effective thickening and moisture retention.
Methylhydroxyethyl cellulose has great film formation in construction projects.


Methylhydroxyethyl cellulose is a non-ionic cellulose ether that widely used in construction materials.
Methylhydroxyethyl cellulose could be dissolved in hot or cold water to form a transparent solution with a particular viscosity.
Methylhydroxyethyl cellulose is a safe, strong, and resistant product you can depend on.


Methylhydroxyethyl cellulose is medium-high viscosity construction grade Methyl Hydroxyethyl Cellulose widely used in building materials.
Methylhydroxyethyl cellulose could be soluble in water to form a transparent solution
Methylhydroxyethyl cellulose is a gelling and thickening agent that is derived from cellulose.


The chemical formula of this compound is variable because the number of unit structures per Methylhydroxyethyl cellulose molecule can vary.
Methylhydroxyethyl cellulose stands for methyl hydroxyethyl cellulose.
Methylhydroxyethyl cellulose is a nonionic cellulose derivative that dissolves readily in water, either cold or hot.


Methylhydroxyethyl cellulose is a gelling and thickening agent derived from cellulose.
Methylhydroxyethyl cellulose, also known as Methylcellulose and colloquium, is an organic compound uses in various cosmetic and medical applications, the primary one being as a thickening agent.


Methylhydroxyethyl cellulose is made from highly pure cotton-cellulose by reaction of etherification under alkaline conditions without any organs of animals, fat and other bioactive constituents.
Methylhydroxyethyl cellulose appears to be white powder and is odorless and tasteless.


Methylhydroxyethyl cellulose could dissolve in water and form a clear solution with specific viscosity.
Also called MHEC, it is short-term for methyl hydroxyethyl cellulose.
Methylhydroxyethyl cellulose's produced from a natural renewable polymer, wood pulp, or refined cotton.


The cold water disperses the model product, can make the mix more quick and convenient, and does not produce the mass.
Generate favorable flow characteristics, including low spatter and good leveling, to ensure fine surface finish and prevent the flow of paint.
In cold water Methylhydroxyethyl cellulose will swell into colloidal solution and its solubility is not influenced by PH value.


Similar to methyl cellulose while being added to Hydroxyethyl groups.
Methylhydroxyethyl cellulose is water soluble, nonionic cellulose ethers, which are offered as free flowing powder or in granular form.
Methylhydroxyethyl cellulose can be used in water-based latex paints and printing inks.


Methylhydroxyethyl cellulose is a non-ionic cellulose ether that evolved from the addition of ethylene oxide to methylcellulose.
Methylhydroxyethyl cellulose is ether of cellulose and ethylene oxide mainly used as adhesive protective gelatin, thicker agent and stabilizing agent as well as additives to make emulsion, frozen gelatin, lotion, eye clear agent, suppository and tablets.


Methylhydroxyethyl cellulose can be white to off-white powder, but it's odorless regardless of color, safe for all animal species, and environmentally friendly.
Methylhydroxyethyl cellulose is a kind of methyl cellulose derivative which is made from natural high polymer cellulose.


Methylhydroxyethyl cellulose is nonionic cellulose ether produced from natural polymer material through the processing of etherification reaction.
Methylhydroxyethyl cellulose enhances the liquidity and pumpability, thus improving the efficiency of the flooring.
The term HPMC stands for hydroxypropyl methyl cellulose, while the term Methylhydroxyethyl cellulose stands for methyl hydroxyethyl cellulose.


These two are important as construction chemicals and can be used as thickeners, water retention agents, and air-entraining agents.
Methylhydroxyethyl cellulose is excellent compatibility with other components and high biostability.
Methylhydroxyethyl cellulose dissolves fast and without mass, which helps to simplify the mixing process.



USES and APPLICATIONS of METHYLHYDROXYETHYL CELLULOSE:
A modified Methylhydroxyethyl cellulose developed for cement-based applications, such as cement-based tile adhesives.
Methylhydroxyethyl cellulose is compatible with all conventional mineral binders used.
Methyl Hydroxyethyl Cellulose (MHEC) alone or in combination is the most widely used cellulose in mortar formulations.


Methylhydroxyethyl cellulose provides many of the same benefits as other methylcellulose derivatives, such as the ability to efficiently thicken and provide water retention, Methylhydroxyethyl cellulose is highly effective additives used to improve the quality and processing characteristics of building materials such as plasters and renders, mortars, tile adhesives, joint compounds and emulsion paints.


Methylhydroxyethyl cellulose provides good open time, slip resistance, adhesion and shear strength, according to different storage conditions.
The selected particle size distribution offers quick, lump free dissolution.
Methylhydroxyethyl cellulose has various properties such as thickening, emulsifying, binding, forming, protective colloid and water retention.


In decorative applications, Methylhydroxyethyl cellulose's found most often as a component of toothpaste and cough syrups.
Methylhydroxyethyl cellulose is tasteless and odorless, and in medicine, it is ingested by patients to relieve constipation, diarrhea, and hemorrhoids.
Methylhydroxyethyl cellulose also enhances workability and water retention.


The most significant Methylhydroxyethyl cellulose uses include its use in the production of adhesives, cosmetics, paper and textiles, pharmaceuticals, paint, and a host of other industrial applications.
Uses of Methylhydroxyethyl cellulose: Cement-based tile adhesives.


Methylhydroxyethyl cellulose has good viscosity stability and anti-mildew degeneration during long-term storage.
Methylhydroxyethyl cellulose has a good performance in coatings and building materials.
Methylhydroxyethyl cellulose used as a high efficient water retention agent, stabilizer, adhesive and film-forming agent in kinds of building materials.


Methylhydroxyethyl cellulose, also known as Hydroxyethyl cellulose or hydroxyethyl ether, is a thickening and gelling agent that comes from cellulose which is used in cleaning solutions and in cosmetics.
Methylhydroxyethyl cellulose is also used in cement-based tile adhesives and grouts.


Methylhydroxyethyl cellulose is widely used in many different industries as water retention agent, thickener, adhesive agent and dispersant etc.
Methylhydroxyethyl cellulose is extruded concrete plank.
Methylhydroxyethyl cellulose enhances the processing performance of extruded products, with high bonding strength and lubrication.


Methylhydroxyethyl cellulose improves the adhesiveness of wet strength and sheet extrusion.
Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.


Mainly, these are used in cement and gypsum-based dry mix mortar to increase bond strength, workability, and water retention.
Methylhydroxyethyl cellulose is a product used for manufacturing of wall putty and tiles adhesives
Methylhydroxyethyl cellulose is non surface treated grade, used for various mortars especially under dry mix system.


Methylhydroxyethyl cellulose offers premium level of water retention and strong adhesion.
Methylhydroxyethyl cellulose (HEMC or MHEC) are excellent thickener and water retaining agents in construction industries for tile glue, grouts, skim coat, and cement render.


Methylhydroxyethyl cellulose is used water based paint and paint remover.
Methylhydroxyethyl cellulose enhances the viscosity of the water-based paint remover and organic solvent, so that the paint remover will not flow out of the surface of the workpiece.


Methylhydroxyethyl cellulose has a good anti-mildew ability because it contains hydroxyethyl groups.
Multiple grades and tailored formulations are available to suit various industrial needs.
Methylhydroxyethyl cellulose is also used to control consistency, flow and leveling, high shear viscosity, and storage stability of interior and exterior flat emulsion paints.


Methylhydroxyethyl cellulose is excellent in water solubility, water retention, surface activity, thickening, film formation, adhesion, suspension, and high-temperature resistance.
Methyl Hydroxyethyl Cellulose (MHEC) is a kind of Cellulose Ethers, which is mainly used as adhesive protective gelatin, thicker agent, stabilizing agent as well as additives to make emulsion, frozen gelatin, lotion, eye clear agent, suppository and tablets


Methylhydroxyethyl cellulose is widely used to maintain water content in waterborne coatings and varnishes, control the rheology and consistency of waterborne coatings, stabilize pigments and fillers, as adhesives and viscosity control agents in enamel, as thickeners in printing inks, and as thickeners in textile coatings.


Methylhydroxyethyl cellulose is widely used in various industries, including tile adhesives, grouts, skim coat/wall putty, cement renders, gypsum-based products, cement-based mortars.
Methylhydroxyethyl cellulose is mainly used as water retaining agent and thickener in cement-based materials.


Methylhydroxyethyl cellulose can also shows delayed solubility.
Due to its high degree of methoxylation, Methylhydroxyethyl cellulose is the only cellulose derivative with the best water retention, which is the only reason why MHEC is sold for use in cement-based wall putties and mortars.


Methylhydroxyethyl cellulose can thicken, suspend, agglutinate, float, and provide protective colloid, for this reason, it is mainly used as an adhesive, thickener, and emulsifying additive.
Methylhydroxyethyl cellulose is a high-efficiency water retention agent because its aqueous solution has good hydrophilicity.


Methylhydroxyethyl cellulose offers premium level of water retention and strong adhesion.
According to experts, Methylhydroxyethyl cellulose also improves the performance of cement and gypsum based materials.
Methylhydroxyethyl cellulose ensures fast hydration for reliable performance.


Methylhydroxyethyl cellulose's water retaining function can prevent the base material from absorbing too much and too quickly and prevent the evaporation of water, so as to ensure that there is enough water when the cement is hydrated.
Methylhydroxyethyl cellulose is a water soluble substance.


For industrial usages, Methylhydroxyethyl cellulose's different forms are: water retention agent, stabilizer, adhesives and film forming agent.
Except for the construction industry, Methylhydroxyethyl cellulose is also used in the food industry, daily chemicals, and other fields.
Methylhydroxyethyl cellulose can increase the workability of mortar.


Methylhydroxyethyl cellulose ensures fast hydration for reliable performance.
To avoid the lump formation, Methylhydroxyethyl cellulose is suggested to use it in dry from before the water is added, as it dissolve rapidly.
In the food industry, Methylhydroxyethyl cellulose is used as adhesion, emulsification, film formation, thickening, suspending, dispersing, water retention agents, etc.


In daily chemicals, Methylhydroxyethyl cellulose is used as an additive for toothpaste, cosmetics, and detergent.
According to experts, Methylhydroxyethyl cellulose also improves the performance of cement and gypsum based materials.
Methylhydroxyethyl cellulose is a water soluble substance.


Methylhydroxyethyl cellulose is used as a food additive.
Methylhydroxyethyl cellulose is also playing useful roles in kinds of building materials.
Methylhydroxyethyl cellulose has stronger water retention than methylcellulose, stronger viscosity stability, mildew resistance, and dispersion than hydroxyethyl cellulose.


Make Methylhydroxyethyl cellulose easier for constructors to operate.
As a non-ionic cellulose ether, Methylhydroxyethyl cellulose powder has a good stabilization and thickening effect in paint, which can make the paint produce good wear resistance.


Methylhydroxyethyl cellulose can be used as the adhesive for plastering mortar, gypsum materials, putty powder and other building materials to improve the coating performance and prolong the service time.
Methylhydroxyethyl cellulose is also playing useful roles in kinds of building materials.


Methylhydroxyethyl cellulose is non surface treated grade, used for various mortars especially under dry mix system.
Methylhydroxyethyl cellulose can be used in different building materials: Tile adhesive, Cement mortar, Joint filler, Self-levelling compound, External wall insulation, Gypsum based plaster, Ceramic extrusion.


Methylhydroxyethyl cellulose cellulose powder is widely used in the building industry.
Methylhydroxyethyl cellulose could dissolve in water and form a clear solution with specific viscosity.
Methylhydroxyethyl cellulose have a good stability even though in alkaline environment and provide a good stability in heat environment.


For industrial usages, Methylhydroxyethyl cellulose's different forms are: water retention agent, stabilizer, adhesives and film forming agent.
Methylhydroxyethyl cellulose can also be used to paste ceramic tiles, marble, plastic decoration, paste reinforcing agent, and reduce the amount of corresponding materials.


Methylhydroxyethyl cellulose offers very good temperature stability and compatibility with many materials including surfactants and polymers such as CMC, starch ether, guar gum and alginates.
Methylhydroxyethyl cellulose is widely used in tile adhesives, dry mix mortar, joint filler, wall putty/skim coat, self-leveling floor, gypsum plaster, EIFS, and detergent.


Methylhydroxyethyl cellulose is widely used in wall putty and tile adhesives.
Methylhydroxyethyl cellulose is widely used in many different industries as water retention agent, thickener, adhesive agent and dispersant etc.
The lubricity of Methylhydroxyethyl cellulose can greatly improve the mortar workability (such as improve the bond strength of mortar, reduce water absorption, and enhance anti-sag of mortar), which is helpful for improving work efficiency.


To avoid the lump formation, Methylhydroxyethyl cellulose is suggested to use it in dry form before the water is added, as it dissolve rapidly.
Methylhydroxyethyl cellulose is widely used in drymix mortar industry, oil drilling, detergent and paint & costings etc.
For example, Methylhydroxyethyl cellulose can be used in tile adhesive, joint filler, self-leveling mortar, plaster, skim coat, paint and coatings, etc.


Methylhydroxyethyl cellulose can be used as a protective colloids, suspending agent and binder and stabilizer.
Methylhydroxyethyl cellulose is widely used in drymix mortar industry, oil drilling, detergent and paint & costings etc.
Methylhydroxyethyl cellulose has several properties used in the pharmaceutical and construction industries.


-Dispersing Agent:
When mixed with other chemicals, Methylhydroxyethyl cellulose works as a dispersing agent because it absorbs water to form a gel while keeping the ingredients in suspension.
This makes Methylhydroxyethyl cellulose useful in various applications, including household products like laundry detergent, foods like whipped cream, cosmetics like toothpaste, and pharmaceuticals like cough syrups or eye drops.


-Uses of Methylhydroxyethyl cellulose:
*Construction:
Cement mortar, Concrete mix, Gypsum-based hand and machine plasters
*Painting:
Latex paint, polymer emulsified, Thickening, water retention, retarding Interior paints Exterior paints
*Silicone resin-based paints, Jamb mortars Papermaking:
Sizing agent, Thickener, water-retaining
*Cosmetics:
Toothpaste, shampoo, Detergent, Thickener, stabilizer
*Petroleum Oil:
Widely used in well drilling, filling liquids, Water retention, Thickening, Liquid loss control industrial applications


-Soil Stabilizers:
Methylhydroxyethyl cellulose is used as a soil stabilizer to increase the yield of crops on marginal land and in areas where irrigation is not practical.
Methylhydroxyethyl cellulose can be mixed with water and applied to soil to improve moisture retention during dry periods or when rainfall is sparse.
When incorporated into fertilizer formulas, Methylhydroxyethyl cellulose allows nutrients to remain available to plants over more extended periods than untreated fertilizers.


-Cement plaster:
Methylhydroxyethyl cellulose improve homogeneity, make the mortar more easily coated, and improve the anti-sagging ability.
Methylhydroxyethyl cellulose enhance liquidity and pumpability, thus improving working efficiency.
High water retention, prolong the working time of mortar, improve work efficiency, and facilitate the formation of high mechanical strength during solidification period.
Control the infiltration of air, thus eliminating the microcracks of the coating and forming the ideal smooth surface.


-Food Production:
Methylhydroxyethyl cellulose is commonly used as an ingredient in the production of commercially-made ice cream due to its ability to stabilize the product.
Methylhydroxyethyl cellulose serves as an alternative to gelatin and vegetable gum such as guar gum and locust bean gum.
Methylhydroxyethyl cellulose is also added to baked goods, salad dressings, and salad gums.
Methylhydroxyethyl cellulose helps prevent sugar crystallization and increases the shelf life of food products by controlling moisture content.


-Moisturizer and surfactant:
Methylhydroxyethyl cellulose is also used as a moisturizer and surfactant in cosmetics, baby lotions, shampoos, and bath oils.
Methylhydroxyethyl cellulose is a wetting agent that lowers the surface tension of liquids and allows them to spread over a surface.
Methylhydroxyethyl cellulose can be used as an emulsifier that keeps water-based and oil-based ingredients mixed in cosmetics.


-Applications of Methylhydroxyethyl cellulose:
*Skim coat / wall putty
*Tile adhesives
*Joint fillers
*Cement mortar/Masonry mortar
*Cement based plasters
*External insulation and finish systems (EIFS)
*Grout
*Self Leveling
*Detergent


-Herbicide:
Some farmers use Methylcellulose as an herbicide. When mixed with water and sprinkled on certain plants, Methylhydroxyethyl cellulose can help prevent growth or kill the plant entirely.
Methylhydroxyethyl cellulose helps the herbicide stay in place without being washed away by water or carried away by the wind.


-Tile adhesive:
Methylhydroxyethyl cellulose makes the dry mixing ingredients easy to mix, and will not produce a mass, thus saving working time.
As the application is faster and more effective, Methylhydroxyethyl cellulose can improve the construction and reduce the cost.
Methylhydroxyethyl cellulose improve the efficiency of tiling by lengthening the cooling time. Provides excellent adhesion effect.
Special development model with high anti-skid resistance can be provided.
Self-leveling the ground material.



-Concrete Mixes:
Concrete mixes using Methylhydroxyethyl cellulose are commonly used for their smoothness and strength.
Methylhydroxyethyl cellulose is used to coat the interior surface of concrete pipes, giving them a uniform thickness that reduces wear over time.
This method also produces lines resistant to cracking when exposed to water, heat, or other harsh conditions.


-Applications
*Wall putty/skim coat
*Plaster/render
*Tile grout
*Plaster/render


-Cosmetics:
Methylhydroxyethyl cellulose is found in many cosmetic products, including hair sprays, shampoos, conditioners, toothpaste, and soaps.
Like other uses for methyl hydroxyethyl cellulose, Methylhydroxyethyl cellulose's used to increase the viscosity of these products and make them easier to apply.


-Cosmetic Uses:
*stabilising agents
*viscosity controlling agents


-Binding agent:
Methylhydroxyethyl cellulose is an excellent binding agent or adhesive because it forms a gel when mixed with water.
Methylhydroxyethyl cellulose is often used in the manufacture of pills and capsules because it binds together different pill components to create uniform tablets that are easy to swallow.


-Applications of Methylhydroxyethyl cellulose:
*Adhesives
*Binders
*Coatings
*Construction


-Masonry mortar:
Strengthen the adhesion of the surface of the masonry, and enhance the water retention, so as to improve the strength of mortar.
Improve the lubrication and plasticity so as to improve the construction performance, and use the mortar made of “guaranteed” cellulose ether to make it easier to apply and save time, and improve the cost-effectiveness.

The model with special high water retention can be used for high absorbent bricks.
Methylhydroxyethyl cellulose is used to fill the material.
Excellent water retention, Methylhydroxyethyl cellulose can prolong cooling time and improve working efficiency.

Methylhydroxyethyl cellulosehas high lubricity, make use easier, smooth.
Methylhydroxyethyl cellulose improves the anti-contractility and crack resistance and improve the surface quality.
Methylhydroxyethyl cellulose provides smooth and uniform texture, and make the joint surface more cohesive.


-Drymix Mortar:
Methylhydroxyethyl cellulose for dry mix mortar increases pumping ability and makes the mortar easy to apply.
Maintain enough moisture in the mortar and reach the best performance.


-Paper Production:
Due to the low toxicity of Methylhydroxyethyl cellulose and its ability to improve the properties of paper while decreasing production costs, MHE has gained wide acceptance in the paper manufacturing industry.
Methylhydroxyethyl cellulose can be used as a dry strength agent in paper production to increase tensile strength without increasing gram mage; it can also be used as a pigment binder in paper coatings and water retention agents in paper due to its good properties as a dispersing agent.


-Cement:
Methylhydroxyethyl cellulose helps increase the efficiency of cement by prolonging water retention and hydration reactions.
This helps reduce the amount of glue required during construction projects, ultimately lowering costs.
Methylhydroxyethyl cellulose can also be added to concrete mixes to improve their structural properties, such as flexural strength, compressive strength, and tensile strength.


-Tile Adhesive:
Methylhydroxyethyl cellulose for tile adhesive significantly improves compatibility and stickiness, reduces moisture evaporation, and makes the tiles firmly attach to the wall or floor without sagging or sliding.


-Medicine:
You may have taken Methylhydroxyethyl cellulose without even knowing it.
That's because Methylhydroxyethyl cellulose has been used in manufacturing pharmaceutical products for decades.
Methylhydroxyethyl cellulose works as an excipient (a sense included with an active drug that binds together all ingredients).
Furthermore, Methylhydroxyethyl cellulose can be used to coat pills and help slow down their release into the body.


-Gypsum plaster:
Methylhydroxyethyl cellulose improve homogeneity, make the mortar more easily coated, and improve the anti-sagging ability to enhance the mobility and pumpability.
Thus, the work efficiency is improved.
High water retention, longer working time of mortar, and high mechanical strength during solidification.
A high quality surface coating is formed by controlling the consistency of the mortar.


-Joint Filler:
Methylhydroxyethyl cellulose for joint filler is stable and durable even at high temperatures, particularly in hot weather, and strong cohesiveness boosts construction performance.
Make the construction more straightforward.


-Oil drilling:
Methylhydroxyethyl cellulose uses is also used in oil drilling operations to thicken liquids used in the exploration process.
This helps ensure that Methylhydroxyethyl cellulose can be pumped through pipes without dripping or spilling, making them less effective at their intended function.


-Applications:
Methylhydroxyethyl cellulose is used tile Grouts, Tiles Adhesive, White Cement based wall putty, Water based Latex Paint, Printing Ink, Oil Drilling, Dry & Wet Mortar series, Construction & Building Material, Retaining Water & improving constructability, Thickening Agent, Decorative Plaster, Gypsum, Detergent etc.


-Wall Putty/Skim Coat:
Methylhydroxyethyl cellulose for wall putty/skim coat is a versatile building material for interior and exterior walls.
Methylhydroxyethyl cellulose restrains water loss and maintains a certain level of moisture.


-Paints and coatings:
Methylhydroxyethyl cellulose, also known as MHEC and Methylcellulose, is a thickening agent used in paints and coatings.
Methylhydroxyethyl cellulose can help prevent paint from sagging and dripping when it dries.

The combination can also help provide the color with extra adhesion, making Methylhydroxyethyl cellulose helpful in constructing buildings.
Methylhydroxyethyl cellulose is commonly used as a thickening agent in decorative paints.

Decorative paints are not as strong as structural paints, so they need thickening agents to help them adhere to walls and other surfaces without breaking apart or peeling away.
Methylhydroxyethyl cellulose provides water resistance to decorative paints, making it more difficult for walls to become damaged by exposure to water.
Methylhydroxyethyl cellulose also helps make paint that has been applied easier to clean.


-EIFS:
EIFS is the short form for Exterior Insulation and Finish Systems. Methylhydroxyethyl cellulose in EIFS provides adhering strength with good consistency and is sag resistant.
Methylhydroxyethyl cellulose improves workability and efficiency.


-Thickening agent:
Methylhydroxyethyl cellulose uses to thickener in cosmetic products such as shampoos and conditioners because it can form a film on hair strands.
This film makes hair appear smooth and shiny.
In addition, Methylhydroxyethyl cellulose coats the hair strands to protect them from water damage.
Because Methylhydroxyethyl cellulose is water-soluble, it does not cause build-up on hair strands after repeated use of the product containing it.


-Detergent:
Detergent grade Methylhydroxyethyl cellulose quickly dissolved in cold water, acted as an efective colloidal protective agent, thickener, emulsifier and dispersant, good viscosity stability during long-term storage.


-Self Leveling:
Methylhydroxyethyl cellulose for self leveling compound is a good suspension agent, applicable for indoor floor coverings, water retention power good for liquidity and achieving a smooth surface.


-Applications
◉ Exterior wall adhesive mortar
◉ Interior and exterior wall putty
◉ Good tensile adhesive strength
◉ Tile adhesive glue
◉ Cement-based mortar
◉ Gypsum-based mortar


-Application of Methylhydroxyethyl cellulose:
Methylhydroxyethyl cellulose was specially designed for cement based applications like cement based tiles adhesives, plasters/ render, skim coats/wall putty & External thermal insulation system.



PROPERTIES OF METHYLHYDROXYETHYL CELLULOSE:
*Water retention and adhesive power
*High-temperature resistance
*Dispersant and suspension ability
*A perfect thickener and film formation agent



FEATURES OF METHYLHYDROXYETHYL CELLULOSE:
◉ Excellent water retention capacity
◉ Good salt-resistant capacity
◉ pH stability
◉ Good film-forming ability
◉ Thickening ability
◉ Extensive enzyme resistance



PHYSICAL PROPERTIES OF METHYLHYDROXYETHYL CELLULOSE:
Methylhydroxyethyl cellulose appears to be white powder and is odorless and tasteless.
Methylhydroxyethyl cellulose is featured by hygroscopicity and hardly soluble in hot water, acetone, ethanol and toluene.
In cold water Methylhydroxyethyl cellulose will swell into colloidal solution and its solybility is not influenced by PH value.
Similar to methyl cellulose while being added to Hdroxyethyl groups.
Methylhydroxyethyl cellulose is more resistant to saline, easily soluble in water and has higher gel temperature.



BENEFITS OF METHYLHYDROXYETHYL CELLULOSE:
*Good open time
*Good adhesion and shear strength
*Good water retention at elevated temperatures
*Good adjustment time



PROPERTIES OF METHYLHYDROXYETHYL CELLULOSE:
● Good thickening / thickening efficiency
● Available in a wide range of molecular weight and viscosity
● Excellent properties as a water-retaining agent
● Excellent resistance to dissolved inorganic salts
● Excellent solution clarity
● Low toxicity and environmental protection
● High water retention
● Long open time
● Good workability
● Good heat resistance



WHAT IS THE DIFFERENCE BETWEEN HPMC AND METHYLHYDROXYETHYL CELLULOSE?
HPMC and Methylhydroxyethyl cellulose are modified cellulose forms that are mainly used as gelling agents for thickening properties in different items.
The key difference between HPMC and Methylhydroxyethyl cellulose is that the gel temperature of HPMC is around 60 – 75 ℃ depending on the group content and different production techniques, whereas the gel temperature of MHEC is usually higher than 80 ℃.



KEY PROPERTIES OF METHYLHYDROXYETHYL CELLULOSE:
- Improves workability
- Reduce water absorption
- Increase adhesion strength



WHY METHYLHYDROXYETHYL CELLULOSE IS BEING PREFERRED OVER HPMC FOR CELLULOSE ETHER?
Cellulose Ether is derived from Cellulose and is a water-soluble compound used in several industries.
It finds its usage mainly in the construction, food, pharmaceutical, and cosmetics industries.
Specifically, Cellulose Ether is primarily used in the construction sector as it acts as a binder, thickener, and water retention agent in construction.

There are different grades of Cellulose Ether, which have their applicability and properties.
The two primary grades of Cellulose Ether HPMC (Hydroxypropyl Methyl Cellulose) and Methylhydroxyethyl cellulose have varied similarities, yet one is more preferred than the other in recent days.

Nowadays, Methylhydroxyethyl cellulose grade of Cellulose Ether is more preferred than the HPMC grade in the construction industry.
Though, both are being utilized widely for increasing bond strength and water retention capacity of a dry mixture of cement and gypsum, few properties differentiate them.
The first property differentiating Methylhydroxyethyl cellulose from HPMC is gel temperature; the gel temperature of MHEC is higher than that of Methylhydroxyethyl cellulose.

The gel temperature of HPMC is around 60°c - 70°c, which varies as per its content and production technique; however, the gel temperature of Methylhydroxyethyl cellulose is generally more than 80°C, which makes it a better alternative.
Methylhydroxyethyl cellulose has better thermal stability owing to its high gel temperature, causing better water retention capacity during summers in South Asian Countries.

Furthermore, Methylhydroxyethyl cellulose has a more significant number of Hydrophilic groups in its structure, eventually leading to more hydrophilicity than the HPMC grade.
Having more Hydrophilic groups makes Methylhydroxyethyl cellulose better in water retention, and hence it is preferred more.
In addition, the prices of Methylhydroxyethyl cellulose grades have been lesser than that of HPMC, making them more economical to use.
In India, the prices of Cellulose Ether, with respective to all grades, have been marginally increasing from the first week of April.

According to ChemAnalyst, “Methylhydroxyethyl cellulosegrade would be chosen over HPMC grade in countries including India as summers have already approached.
Construction industries would go for having cellulose ether with higher gel temperature and better hydrophilicity.
Furthermore, the Indian domestic market of Cellulose Ether is most likely to showcase stagnant to a marginal rise in the prices.”



PHYSICAL and CHEMICAL PROPERTIES of METHYLHYDROXYETHYL CELLULOSE:
Appearance: white or off-white
Moisture: ≤5%
Ash: ≤5%
Etherification(MS/DS): 0.8-1.2/1.8-2.0
pH value: 6-8
Gel temperature: 70-85°C
Viscosity: 1,000-75,000 mPa.s (Brookfield RV, 2%)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Molecular Weight: 858.9
Hydrogen Bond Donor Count: 10
Hydrogen Bond Acceptor Count: 24
Rotatable Bond Count: 17
Exact Mass: 858.39440297
Monoisotopic Mass: 858.39440297
Topological Polar Surface Area: 332 Ų
Heavy Atom Count: 58
Formal Charge: 0
Complexity: 884
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 20
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Appearance: White powder
Loss on drying: ≤5%
PH: 4.0-8.0



FIRST AID MEASURES of METHYLHYDROXYETHYL CELLULOSE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated lothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of METHYLHYDROXYETHYL CELLULOSE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of METHYLHYDROXYETHYL CELLULOSE:
-Extinguishing media:
*Suitable extinguishing media:
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of METHYLHYDROXYETHYL CELLULOSE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 240 min
*Body Protection:
Flame retardant antistatic protective clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of METHYLHYDROXYETHYL CELLULOSE:
-Precautions for safe handling:
*Advice on protection against fire and explosion:
Take precautionary measures against static discharge.
*Hygiene measures:
Change contaminated clothing.
Preventive skin protection recommended.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of METHYLHYDROXYETHYL CELLULOSE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available



SYNONYMS:
(2S,3R,4R,5S,6R)-2-(hydroxymethyl)-6-[(2S,3R,4S,5S,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
(2S,3S,4R,5S,6S)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2R,3S,4R,5S,6S)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane
2-hydroxyethyl methyl cellulose
Cellulose, 2-hydroxyethyl methyl ether
Methyl hydroxyethyl cellulose
9032-42-2
methyl 2-hydroxyethyl cellulose
ethane-1,2-diol



METHYLHYDROXYETHYL CELLULOSE
DESCRIPTION:

Methylhydroxyethyl cellulose (MHEC) is a gelling and thickening agent derived from cellulose.
Methylhydroxyethyl cellulose (MHEC) is short-term for methyl hydroxyethyl cellulose.
Methylhydroxyethyl cellulose (MHEC)'s produced from a natural renewable polymer, wood pulp, or refined cotton.



CAS NUMBER: 9032-42-2

MOLECULAR FORMULA: C34H66O24

MOLECULAR WEIGHT: 858.9 g/mol



DESCRIPTION:

Methylhydroxyethyl cellulose (MHEC) is a non-ionic cellulose ether that evolved from the addition of ethylene oxide to methylcellulose.
Methylhydroxyethyl cellulose (MHEC) can be white to off-white powder, but it's odorless regardless of color, safe for all animal species, and environmentally friendly.
Methylhydroxyethyl cellulose (MHEC) is widely used in tile adhesives, dry mix mortar, joint filler, wall putty/skim coat, self-leveling floor, gypsum plaster, EIFS, and detergent.
Methylhydroxyethyl cellulose (MHEC) is non-ionic cellulose ether produced from natural polymer material through the processing of etherification reaction.
Methylhydroxyethyl cellulose (MHEC) is a kind of odorless and tasteless.

Methylhydroxyethyl cellulose (MHEC) is an off-white powder or granule.
Methylhydroxyethyl cellulose (MHEC) dissolves in hot and cold water, forms a transparent viscous solution and is insoluble in common organic solvents.
Methylhydroxyethyl cellulose (MHEC) ether can be used in any area where thickening, gelling, emulsifying, stabilizing processes and providing water retention and good workability properties are required.
Methylhydroxyethyl cellulose (MHEC) is a synthetic substance that is used as a thickening and emulsifying agent in many products, including foods, pharmaceuticals, and cosmetics.

Methylhydroxyethyl cellulose (MHEC) has been shown to inhibit the activity of certain enzymes, such as amylase, lipase, and protease.
In addition to these properties, Methylhydroxyethyl cellulose (MHEC) is also known for its high degree of thermal stability and light resistance.
Methylhydroxyethyl cellulose (MHEC) can be used in a wide range of applications due to its versatility and low cost.
Methylhydroxyethyl cellulose (MHEC) provides many of the same benefits as other methylcellulose derivatives, such as the ability to efficiently thicken and provide water retention.
Methylhydroxyethyl cellulose (MHEC) are highly effective additives used to improve the quality and processing characteristics of building materials such as plasters and renders, mortars, tile adhesives, joint compounds and emulsion paints.

Methylhydroxyethyl cellulose (MHEC) is an organic compound methyl hydroxyethyl cellulose uses in various cosmetic and medical applications, the primary one being as a thickening agent.
Methylhydroxyethyl cellulose (MHEC)'s found most often as a component of toothpaste and cough syrups.
Methylhydroxyethyl cellulose (MHEC) uses to thickener in cosmetic products such as shampoos and conditioners because it can form a film on hair strands.
This film makes hair appear smooth and shiny.
In addition, the material coats the hair strands to protect them from water damage.

Methylhydroxyethyl cellulose (MHEC) is water-soluble, methyl hydroxyethyl cellulose does not cause build-up on hair strands after repeated use of the product containing it.
Methylhydroxyethyl cellulose (MHEC) is a non-ionic water-soluble polymer.
Methylhydroxyethyl cellulose (MHEC) has been used in manufacturing pharmaceutical products for decades.
Methylhydroxyethyl cellulose (MHEC) works as an excipient (a sense included with an active drug that binds together all ingredients).

Methylhydroxyethyl cellulose (MHEC) can be used to coat pills and help slow down their release into the body.
Methylhydroxyethyl cellulose (MHEC) is an excellent binding agent or adhesive because it forms a gel when mixed with water.
Methylhydroxyethyl cellulose (MHEC) is often used in the manufacture of pills and capsules because it binds together different pill components to create uniform tablets that are easy to swallow.
Due to the low toxicity of Methylhydroxyethyl cellulose (MHEC) and its ability to improve the properties of paper while decreasing production costs, Methylhydroxyethyl cellulose (MHEC) has gained wide acceptance in the paper manufacturing industry.

Methylhydroxyethyl cellulose (MHEC) can be used as a dry strength agent in paper production to increase tensile strength without increasing gram mage.
Methylhydroxyethyl cellulose (MHEC) can also be used as a pigment binder in paper coatings and water retention agents in paper due to its good properties as a dispersing agent.
When mixed with other chemicals, Methylhydroxyethyl cellulose (MHEC) works as a dispersing agent because it absorbs water to form a gel while keeping the ingredients in suspension.

This makes it useful in various applications, including household products like laundry detergent, foods like whipped cream, cosmetics like toothpaste, and pharmaceuticals like cough syrups or eye drops.
Methylhydroxyethyl cellulose (MHEC) is used as a soil stabilizer to increase the yield of crops on marginal land and in areas where irrigation is not practical.
Methylhydroxyethyl cellulose (MHEC) can be mixed with water and applied to soil to improve moisture retention during dry periods or when rainfall is sparse.
When incorporated into fertilizer formulas, Methylhydroxyethyl cellulose (MHEC) allows nutrients to remain available to plants over more extended periods than untreated fertilizers.

Methylhydroxyethyl cellulose (MHEC) is also used as a moisturizer and surfactant in cosmetics, baby lotions, shampoos, and bath oils.
A surfactant is a wetting agent that lowers the surface tension of liquids and allows them to spread over a surface.
Methylhydroxyethyl cellulose (MHEC) can be used as an emulsifier that keeps water-based and oil-based ingredients mixed in cosmetics.
Concrete mixes using Methylhydroxyethyl cellulose (MHEC) are commonly used for their smoothness and strength.
Methylhydroxyethyl cellulose (MHEC) is used to coat the interior surface of concrete pipes, giving them a uniform thickness that reduces wear over time.
This method also produces lines resistant to cracking when exposed to water, heat, or other harsh conditions.

Methylhydroxyethyl cellulose (MHEC) is commonly used as an ingredient in the production of commercially-made ice cream due to its ability to stabilize the product.
Methylhydroxyethyl cellulose (MHEC) serves as an alternative to gelatin and vegetable gum such as guar gum and locust bean gum.
Methylhydroxyethyl cellulose (MHEC) is also added to baked goods, salad dressings, and salad gums.
Methylhydroxyethyl cellulose (MHEC) helps prevent sugar crystallization and increases the shelf life of food products by controlling moisture content.
Methylhydroxyethyl cellulose (MHEC) helps increase the efficiency of cement by prolonging water retention and hydration reactions.

Methylhydroxyethyl cellulose (MHEC) helps reduce the amount of glue required during construction projects, ultimately lowering costs.
Methylhydroxyethyl cellulose (MHEC) can also be added to concrete mixes to improve their structural properties, such as flexural strength, compressive strength, and tensile strength.
A modified Methylhydroxyethyl cellulose (MHEC) developed for gypsum-based applications, such as gypsum manualr and spray plasters.
Compatible with all conventional mineral binders used in plaster formulation, Methylhydroxyethyl cellulose (MHEC) provides good mixing properties through adopted particle morphology,high water retentions and adjusted plaster workability, according to specific application segment.
The selected particle size distribution offers quick, lump free dissolution. and prevents the formation of lumps during mixing.

Methylhydroxyethyl cellulose (MHEC) is a nonionic cellulose derivative that dissolves readily in water, either cold or hot.
Methylhydroxyethyl cellulose (MHEC) is a thickening and gelling agent that comes from cellulose which is used in cleaning solutions and in cosmetics.
Methylhydroxyethyl cellulose (MHEC) is a non-ionic, water soluble cellulose ether intended as a water retaining and consistency improving additive to cement based mortars.
Methylhydroxyethyl cellulose (MHEC) is a non-ionic cellulose ether polymer based on cellulose, a natural polymer derived from refine cotton linter.
Methylhydroxyethyl cellulose (MHEC) is a non-ionic cellulose ether made from natural high polymer cellulose.

Methylhydroxyethyl cellulose (MHEC) is an odourless, tasteless and non-toxic white powder, which can be dissolved in cold water to form a transparent viscous solution.
Methylhydroxyethyl cellulose (MHEC) can be used in different building materials.
Methylhydroxyethyl cellulose (MHEC) uses is also used in oil drilling operations to thicken liquids used in the exploration process.
Methylhydroxyethyl cellulose (MHEC) helps ensure that the fluid can be pumped through pipes without dripping or spilling, making them less effective at their intended function.

Methylhydroxyethyl cellulose (MHEC) is used as an excipient in a wide range of pharmaceutical products, including oral tablets and suspensions, and topical gel preparations.
Methylhydroxyethyl cellulose (MHEC) has similar properties to methylcellulose, but the hydroxyethyl groups make it more readily soluble in water and solutions are more tolerant of salts and have a higher coagulation temperature.
Methylhydroxyethyl cellulose (MHEC) is found in many cosmetic products, including hair sprays, shampoos, conditioners, toothpaste, and soaps.
Methylhydroxyethyl cellulose (MHEC) is a thickening agent used in paints and coatings.

Methylhydroxyethyl cellulose (MHEC) can help prevent paint from sagging and dripping when it dries.
The combination can also help provide the color with extra adhesion, making it helpful in constructing buildings.
Methylhydroxyethyl cellulose (MHEC) is commonly used as a thickening agent in decorative paints.
Decorative paints are not as strong as structural paints, so they need thickening agents to help them adhere to walls and other surfaces without breaking apart or peeling away.
Methylhydroxyethyl cellulose (MHEC) provides water resistance to decorative paints, making it more difficult for walls to become damaged by exposure to water.

Methylhydroxyethyl cellulose (MHEC) also helps make paint that has been applied easier to clean.
Methylhydroxyethyl cellulose (MHEC) is a cellulose ether, which is based on methyl cellulose.
Methylhydroxyethyl cellulose (MHEC) has several properties in pharma and construction industries.
Methylhydroxyethyl cellulose (MHEC) is better performance in terms of higher gel temperature and hydrophilicity rely on ethyl substituent groups.
Methylhydroxyethyl cellulose (MHEC) is excellent thickener and water retaining agents in construction industries for tile glue, grouts, skim coat, and cement render.



USES:

-Water retention aid
-thickening agent
-protective colloid
-suspending agent
-binder and stabilizer
-Gypsum spray plaster
-Gypsum manual plaster
-Lime gypsum plaster




USAGE AREAS:

Construction:

-Cement mortar
-Concrete mix
-Gypsum-based hand and Machine plasters


Painting:

-Latex paint
-polymer emulsified
-Thickening
-water retention
-retarding Interior paints Exterior paints Silicone resin-based paints
-Jam mortars


Papermaking:

-Sizing agent
-Thickener
-waterstop


Cosmetics:

-Toothpaste
-shampoo
-Detergent
-Thickener
-stabilizer



USAGE:

-Drymix Mortar
-Drymix Mortar
-Paint & Coatings
-Home Care
-Ceramic



APPLICATION:

HBR can be used as a protective colloid, stabilizer and suspending agent.
It offers very good pseudoplastic flow characteristics and broad compatibility with other materials such as emulsion polymers, natural and synthetic gums, emulsifiers, defoamers, pigments, surfactants and preservatives.


-Interior wall latex paint
-Exterior wall latex paint
-Real stone paint
-Texture paint



BENEFITS:

-Good mixing properties
-Improved workability
-Good water retention at elevated temperatures
-High standing strength



FEATURES:

-Water retention and adhesive power
-High-temperature resistance
-Dispersant and suspension ability
-A perfect thickener and film formation agent
-Excellent stability against enzymes
-Good solubility, easy to use
-Excellent viscosity stability
-Excellent water retention, extended open time
-Suitable for various lotion types



SPECIFICATION:

-Appearance: white or off-white
-Moisture: ≤5%
-Ash: ≤5%
-Etherification(MS/DS): 0.8-1.2/1.8-2.0
-pH value: 6-8
-Gel temperature: 70-85°C
-Viscosity: 1,000-75,000 mPa.s (Brookfield RV, 2%)



PROPERTIES:

-Purity: 98%
-Type: Powder
-Usage: Coating Auxiliary Agents
-Model Number: 250 HHBR
-Appearance: POWDER
-Moisture content, %,: max 5
-Color: white
-Ash content %,: maximum: 5.5
-Hydration time at pH 8.0: 4-25 minutes
-Viscosity: 3400-5000 cps
-Density g/ml: 1.38



PROPERTIES:

-Appearance: White and off-white powder
-Particle size: 98% — 100%
-Moisture content (%): ≤5.0
-PH value: 5.0-8.0



SPECIFICATION:

-surface tension: 45-55 dyn/cm, 20 °C, 0.1 wt. %
-viscosity: 15,000-20,500 cP, 2 wt. % in H2O(20 °C, Brookfield, spindle #6) (20 rpm)(lit.)
-transition temp: flocculation range 60-90 °C (0.5 wt. %)
-Molecular Weight: 858.9 g/mol
-Hydrogen Bond Donor Count: 10
-Hydrogen Bond Acceptor Count: 24
-Rotatable Bond Count: 17
-Exact Mass: 858.39440297 g/mol
-Monoisotopic Mass: 858.39440297 g/mol
-Topological Polar Surface Area: 332Ų
-Heavy Atom Count: 58
-Complexity: 884
-Isotope Atom Count: 0
-Defined Atom Stereocenter Count: 0
-Undefined Atom Stereocenter Count: 20
-Defined Bond Stereocenter Count: 0
-Undefined Bond Stereocenter Count: 0
-Covalently-Bonded Unit Count: 3
-Compound Is Canonicalized: Yes



STORAGE:

Hydroxyethylmethyl cellulose is hygroscopic and should therefore be stored under dry conditions away from heat.



SYNONYM:

methyl 2-hydroxyethyl cellulose
9032-42-2
FT-0612598
METHYLHYDROXYETHYL CELLULOSE (MHEC)
Methylhydroxyethyl cellulose (MHEC) is a gelling and thickening agent derived from cellulose.
Methylhydroxyethyl cellulose (MHEC), also known as Methylcellulose and colloquium, is an organic compound methyl hydroxyethyl cellulose uses in various cosmetic and medical applications, the primary one being as a thickening agent.


CAS Number: 9032-42-2
Chemical formula: variable


Methylhydroxyethyl cellulose (MHEC) is nonionic cellulose ether produced from natural polymer material through the processing of etherification reaction.
Methylhydroxyethyl cellulose (MHEC) is a kind of odorless, tasteless, non-toxic white powder or granule.
Methylhydroxyethyl cellulose (MHEC) dissolves in hot and cold water, forms a transparent viscous solution and is insoluble in common organic solvents.


Methylhydroxyethyl cellulose (MHEC) is a white, odorless powder.
Methylhydroxyethyl cellulose (MHEC) is ether of cellulose and ethylene oxide mainly used as adhesive protective gelatin, thicker agent and stabilizing agent as well as additives to make emulsion, frozen gelatin, lotion, eye clear agent, suppository and tablets.


Methylhydroxyethyl cellulose (MHEC) is a water soluble.
The term HPMC stands for hydroxypropyl methyl cellulose, while the term Methylhydroxyethyl cellulose (MHEC) stands for methyl hydroxyethyl cellulose.
These two are important as construction chemicals and can be used as thickeners, water retention agents, and air-entraining agents.


Methylhydroxyethyl cellulose (MHEC) stands for methyl hydroxyethyl cellulose.
Methylhydroxyethyl cellulose (MHEC) is a gelling and thickening agent that is derived from cellulose.
The chemical formula of this compound is variable because the number of unit structures per Methylhydroxyethyl cellulose (MHEC) molecule can vary.


Therefore, the molar mass also varies accordingly.
Methylhydroxyethyl cellulose (MHEC) is considered to be non-toxic.
Methylhydroxyethyl cellulose (MHEC) can be described as a modified cellulose polymer consisting of methyl, ethyl, and hydroxyethyl side chains.


Methylhydroxyethyl cellulose (MHEC) is a nonionic cellulose derivative that dissolves readily in water, either cold or hot.
Compared to other cellulose ether chemistries, the methylcellulose derivatives have a slightly more Newtonian flow characteristic which provides increased high-shear (ICI) viscosity.


Methylhydroxyethyl cellulose (MHEC) is water soluble, nonionic cellulose ethers, which are offered as free flowing powder or in granular form.
Methylhydroxyethyl cellulose (MHEC) may contain further additives which for example control the dissolution behavior or the thickening power.
Methyl Hydroxyethyl Cellulose (MHEC), in the form of a powder, is a thickening agent.


Methylhydroxyethyl cellulose (MHEC) can be used in water-based latex paints and printing inks.
Methylhydroxyethyl cellulose (MHEC)'s pH value exists between 5.0 and 8.0.
Methylhydroxyethyl cellulose (MHEC) is water soluble nonionic cellulose ethers, which are offered as free flowing powder or in granular form cellulose.


Methylhydroxyethyl cellulose (MHEC) is made from highly pure cotton-cellulose by reaction of etherification under alkaline conditions without any organs of animals, fat and other bioactive constituents.
Methylhydroxyethyl cellulose (MHEC) appears to be white powder and is odorless and tasteless.


Methylhydroxyethyl cellulose (MHEC) is featured by hygroscopicity and hardly soluble in hot water, acetone, ethanol and toluene.
In cold water Methylhydroxyethyl cellulose (MHEC) will swell into colloidal solution and its solubility is not influenced by PH value.
Similar to methyl cellulose while being added to Hydroxyethyl groups.


Methylhydroxyethyl cellulose (MHEC) is more resistant to saline, easily soluble in water and has higher gel temperature. Methylhydroxyethyl cellulose (MHEC) is also known as HEMC, Methyl Hydroxyethyl Cellulose, which can be used as highly efficient water retention agent, stabilizer, adhesives and film-forming agent in construct.
Methylhydroxyethyl cellulose (MHEC) is a kind of methyl cellulose derivative which is made from natural high polymer cellulose.


Methylhydroxyethyl cellulose (MHEC) is medium-high viscosity construction grade Methyl Hydroxyethyl Cellulose widely used in building materials.
Methylhydroxyethyl cellulose (MHEC) could be soluble in water to form a transparent solution
Methylhydroxyethyl cellulose (MHEC) is a non-ionic cellulose ether that widely used in construction materials.


Methylhydroxyethyl cellulose (MHEC) could be dissolved in hot or cold water to form a transparent solution with a particular viscosity.
The properties of Methylhydroxyethyl cellulose (MHEC) and methylcellulose are similar, but the presence of hydroxyethyl makes Methylhydroxyethyl cellulose (MHEC) cellulose more soluble in water, the solution is more compatible with salt and has a higher aggregation temperature.


Methylhydroxyethyl cellulose (MHEC) is a non-ionic cellulose ether made from natural high polymer cellulose.
Methylhydroxyethyl cellulose (MHEC) is an odourless, tasteless and non-toxic white powder, which can be dissolved in cold water to form a transparent viscous solution.
Methylhydroxyethyl cellulose (MHEC) is made from highly pure cotton-cellulose by reaction of etherification under alkaline conditions without any organs of animals, fat and other bioactive constituents.


Methylhydroxyethyl cellulose (MHEC) is also called as Hydroxyethyl Methyl Cellulose HEMC.
Methylhydroxyethyl cellulose (MHEC) is a non-ionic cellulose ether made from natural high polymer cellulose.
Methylhydroxyethyl cellulose (MHEC) offers many of the same advantages as other methyl cellulose derivatives, such as effective thickening and moisture retention.


Methylhydroxyethyl cellulose (MHEC) is a white, yellow-white or off-white powder or granules, hygroscopic after drying.
Methylhydroxyethyl cellulose (MHEC) is a methylcellulose based cellulose.
Methylhydroxyethyl cellulose (MHEC) is a kind of methyl cellulose derivative which is made from natural high polymer cellulose.


Methylhydroxyethyl cellulose (MHEC) could dissolve in water and form a clear solution with specific viscosity.
Methylhydroxyethyl cellulose (MHEC) has a good stability even though in alkaline environment and provide a good stability in heat environment.
Methylhydroxyethyl cellulose (MHEC) provides viscosity, which can be used as an anti – precipitation agent.


Methylhydroxyethyl cellulose (MHEC) enhances the liquidity and pumpability, thus improving the efficiency of the flooring.
Control water retention, thus greatly reducing cracking and shrinkage.
Methylhydroxyethyl cellulose (MHEC) is excellent compatibility with other components and high biostability.


Methylhydroxyethyl cellulose (MHEC) dissolves fast and without mass, which helps to simplify the mixing process.
The cold water disperses the model product, can make the mix more quick and convenient, and does not produce the mass.
Generate favorable flow characteristics, including low spatter and good leveling, to ensure fine surface finish and prevent the flow of paint.



USES and APPLICATIONS of METHYLHYDROXYETHYL CELLULOSE (MHEC):
The most significant Methylhydroxyethyl cellulose (MHEC) uses include its use in the production of adhesives, cosmetics, paper and textiles, pharmaceuticals, paint, and a host of other industrial applications.
Cellulose ether can be used in any area where thickening, gelling, emulsifying, stabilizing processes and providing water retention and good workability properties are required.


Methylhydroxyethyl cellulose (MHEC) provides many of the same benefits as other methylcellulose derivatives, such as the ability to efficiently thicken and provide water retention, Methylhydroxyethyl cellulose (MHEC) is highly effective additives used to improve the quality and processing characteristics of building materials such as plasters and renders, mortars, tile adhesives, joint compounds and emulsion paints.


Methylhydroxyethyl cellulose (MHEC) can thicken, suspend, agglutinate, float, and provide protective colloid, for this reason, it is mainly used as an adhesive, thickener, and emulsifying additive.
Methylhydroxyethyl cellulose (MHEC) is a high-efficiency water retention agent because its aqueous solution has good hydrophilicity.


Methylhydroxyethyl cellulose (MHEC) has a good anti-mildew ability because it contains hydroxyethyl groups.
Methylhydroxyethyl cellulose (MHEC) has good viscosity stability and anti-mildew degeneration during long-term storage.
Methylhydroxyethyl cellulose (MHEC) has a good performance in coatings and building materials.


Methylhydroxyethyl cellulose (MHEC) has stronger water retention than methylcellulose, stronger viscosity stability, mildew resistance, and dispersion than hydroxyethyl cellulose.
Methylhydroxyethyl cellulose (MHEC) used as a high efficient water retention agent, stabilizer, adhesive and film-forming agent in kinds of building materials.


In decorative applications, Methylhydroxyethyl cellulose (MHEC)'s found most often as a component of toothpaste and cough syrups.
Methylhydroxyethyl cellulose (MHEC) is tasteless and odorless, and in medicine, it is ingested by patients to relieve constipation, diarrhea, and hemorrhoids.
Mainly, these are used in cement and gypsum-based dry mix mortar to increase bond strength, workability, and water retention.


Therefore, Methylhydroxyethyl cellulose (MHEC) is used as a food additive.
Methyl Hydroxyethyl Cellulose (MHEC) is a kind of Cellulose Ethers, which is mainly used as adhesive protective gelatin, thicker agent, stabilizing agent as well as additives to make emulsion, frozen gelatin, lotion, eye clear agent, suppository and tablets


Methylhydroxyethyl cellulose (MHEC) is a water soluble substance.
For industrial usages, Methylhydroxyethyl cellulose (MHEC)'s different forms are: water retention agent, stabilizer, adhesives and film forming agent.
Methylhydroxyethyl cellulose (MHEC) is also playing useful roles in kinds of building materials.


Methylhydroxyethyl cellulose (MHEC) is non surface treated grade, used for various mortars especially under dry mix system.
Methylhydroxyethyl cellulose (MHEC) offers premium level of water retention and strong adhesion.
According to experts, Methylhydroxyethyl cellulose (MHEC) also improves the performance of cement and gypsum based materials.


Methylhydroxyethyl cellulose (MHEC) ensures fast hydration for reliable performance.
To avoid the lump formation, Methylhydroxyethyl cellulose (MHEC) is suggested to use it in dry from before the water is added, as it dissolve rapidly.
Methylhydroxyethyl cellulose (MHEC) is a water soluble substance.


For industrial usages, Methylhydroxyethyl cellulose (MHEC)'s different forms are: water retention agent, stabilizer, adhesives and film forming agent.
Methylhydroxyethyl cellulose (MHEC) is also playing useful roles in kinds of building materials.
Methylhydroxyethyl cellulose (MHEC) is non surface treated grade, used for various mortars especially under dry mix system.


Methylhydroxyethyl cellulose (MHEC) offers premium level of water retention and strong adhesion.
According to experts, Methylhydroxyethyl cellulose (MHEC) also improves the performance of cement and gypsum based materials.
Methylhydroxyethyl cellulose (MHEC) ensures fast hydration for reliable performance.


To avoid the lump formation, Methylhydroxyethyl cellulose (MHEC) is suggested to use it in dry form before the water is added, as it dissolve rapidly.
Methylhydroxyethyl cellulose (MHEC) is widely used in wall putty and tile adhesives.
Methylhydroxyethyl cellulose (MHEC) is widely used in many different industries as water retention agent, thickener, adhesive agent and dispersant etc.


Methylhydroxyethyl cellulose (MHEC) could dissolve in water and form a clear solution with specific viscosity.
Methylhydroxyethyl cellulose (MHEC) have a good stability even though in alkaline environment and provide a good stability in heat environment.
Methylhydroxyethyl cellulose (MHEC) is widely used in drymix mortar industry, oil drilling, detergent and paint & costings etc.


Methylhydroxyethyl cellulose (MHEC) can be used in different building materials: Tile adhesive, Cement mortar, Joint filler, Self-levelling compound, External wall insulation, Gypsum based plaster, Ceramic extrusion.
Methylhydroxyethyl cellulose (MHEC) cellulose powder is widely used in the building industry.


For example, Methylhydroxyethyl cellulose (MHEC) can be used in tile adhesive, joint filler, self-leveling mortar, plaster, skim coat, paint and coatings, etc.
As a non-ionic cellulose ether, Methylhydroxyethyl cellulose (MHEC) powder has a good stabilization and thickening effect in paint, which can make the paint produce good wear resistance.


The lubricity of Methylhydroxyethyl cellulose (MHEC) can greatly improve the mortar workability (such as improve the bond strength of mortar, reduce water absorption, and enhance anti-sag of mortar), which is helpful for improving work efficiency.
Except for the construction industry, Methylhydroxyethyl cellulose (MHEC) is also used in the food industry, daily chemicals, and other fields.


In the food industry, Methylhydroxyethyl cellulose (MHEC) is used as adhesion, emulsification, film formation, thickening, suspending, dispersing, water retention agents, etc.
In daily chemicals, Methylhydroxyethyl cellulose (MHEC) is used as an additive for toothpaste, cosmetics, and detergent.


Methylhydroxyethyl cellulose (MHEC) is widely used to maintain water content in waterborne coatings and varnishes, control the rheology and consistency of waterborne coatings, stabilize pigments and fillers, as adhesives and viscosity control agents in enamel, as thickeners in printing inks, and as thickeners in textile coatings.
Methylhydroxyethyl cellulose (MHEC) can be used as a protective colloids, suspending agent and binder and stabilizer.


Methylhydroxyethyl cellulose (MHEC) offers very good temperature stability and compatibility with many materials including surfactants and polymers such as CMC, starch ether, guar gum and alginates.
Methylhydroxyethyl cellulose (MHEC) is also used to control consistency, flow and leveling, high shear viscosity, and storage stability of interior and exterior flat emulsion paints.


Methylhydroxyethyl cellulose (MHEC) can also shows delayed solubility.
Due to its high degree of methoxylation, Methylhydroxyethyl cellulose (MHEC) is the only cellulose derivative with the best water retention, which is the only reason why MHEC is sold for use in cement-based wall putties and mortars.


Methylhydroxyethyl cellulose (MHEC) is also used in cement-based tile adhesives and grouts.
Methylhydroxyethyl cellulose (MHEC) is widely used in many different industries as water retention agent, thickener, adhesive agent and dispersant etc.
Methylhydroxyethyl cellulose (MHEC) is widely used in drymix mortar industry, oil drilling, detergent and paint & costings etc.


Methylhydroxyethyl cellulose (MHEC) has several properties used in the pharmaceutical and construction industries.
Methyl Hydroxyethyl Cellulose (MHEC) alone or in combination is the most widely used cellulose in mortar formulations.
Methylhydroxyethyl cellulose (MHEC) has various properties such as thickening, emulsifying, binding, forming, protective colloid and water retention.


Methylhydroxyethyl cellulose (MHEC) is used water based paint and paint remover.
Methylhydroxyethyl cellulose (MHEC) enhances the viscosity of the water-based paint remover and organic solvent, so that the paint remover will not flow out of the surface of the workpiece.


Methylhydroxyethyl cellulose (MHEC) is extruded concrete plank.
Methylhydroxyethyl cellulose (MHEC) enhances the processing performance of extruded products, with high bonding strength and lubrication.
Methylhydroxyethyl cellulose (MHEC) improves the adhesiveness of wet strength and sheet extrusion.


-Applications:
Methylhydroxyethyl cellulose (MHEC) is used tile Grouts, Tiles Adhesive, White Cement based wall putty, Water based Latex Paint, Printing Ink, Oil Drilling, Dry & Wet Mortar series, Construction & Building Material, Retaining Water & improving constructability, Thickening Agent, Decorative Plaster, Gypsum, Detergent etc.


-Thickening agent:
Methylhydroxyethyl cellulose (MHEC) uses to thickener in cosmetic products such as shampoos and conditioners because it can form a film on hair strands.
This film makes hair appear smooth and shiny.
In addition, Methylhydroxyethyl cellulose (MHEC) coats the hair strands to protect them from water damage.
Because Methylhydroxyethyl cellulose (MHEC) is water-soluble, it does not cause build-up on hair strands after repeated use of the product containing it.


-Medicine:
You may have taken Methylhydroxyethyl cellulose (MHEC) without even knowing it.
That's because Methylhydroxyethyl cellulose (MHEC) has been used in manufacturing pharmaceutical products for decades.
Methylhydroxyethyl cellulose (MHEC) works as an excipient (a sense included with an active drug that binds together all ingredients).
Furthermore, Methylhydroxyethyl cellulose (MHEC) can be used to coat pills and help slow down their release into the body.


-Binding agent:
Methylhydroxyethyl cellulose (MHEC) is an excellent binding agent or adhesive because it forms a gel when mixed with water.
Methylhydroxyethyl cellulose (MHEC) is often used in the manufacture of pills and capsules because it binds together different pill components to create uniform tablets that are easy to swallow.


-Paper Production:
Due to the low toxicity of Methylhydroxyethyl cellulose (MHEC) and its ability to improve the properties of paper while decreasing production costs, MHE has gained wide acceptance in the paper manufacturing industry.
Methylhydroxyethyl cellulose (MHEC) can be used as a dry strength agent in paper production to increase tensile strength without increasing gram mage; it can also be used as a pigment binder in paper coatings and water retention agents in paper due to its good properties as a dispersing agent.


-Dispersing Agent:
When mixed with other chemicals, Methylhydroxyethyl cellulose (MHEC) works as a dispersing agent because it absorbs water to form a gel while keeping the ingredients in suspension.
This makes Methylhydroxyethyl cellulose (MHEC) useful in various applications, including household products like laundry detergent, foods like whipped cream, cosmetics like toothpaste, and pharmaceuticals like cough syrups or eye drops.


-Soil Stabilizers:
Methylhydroxyethyl cellulose (MHEC) is used as a soil stabilizer to increase the yield of crops on marginal land and in areas where irrigation is not practical.
Methylhydroxyethyl cellulose (MHEC) can be mixed with water and applied to soil to improve moisture retention during dry periods or when rainfall is sparse.
When incorporated into fertilizer formulas, Methylhydroxyethyl cellulose (MHEC) allows nutrients to remain available to plants over more extended periods than untreated fertilizers.


-Moisturizer and surfactant:
Methylhydroxyethyl cellulose (MHEC) is also used as a moisturizer and surfactant in cosmetics, baby lotions, shampoos, and bath oils.
Methylhydroxyethyl cellulose (MHEC) is a wetting agent that lowers the surface tension of liquids and allows them to spread over a surface.
Methylhydroxyethyl cellulose (MHEC) can be used as an emulsifier that keeps water-based and oil-based ingredients mixed in cosmetics.


-Herbicide:
Some farmers use Methylcellulose as an herbicide. When mixed with water and sprinkled on certain plants, Methylhydroxyethyl cellulose (MHEC) can help prevent growth or kill the plant entirely.
Methylhydroxyethyl cellulose (MHEC) helps the herbicide stay in place without being washed away by water or carried away by the wind.


-Concrete Mixes:
Concrete mixes using Methylhydroxyethyl cellulose (MHEC) are commonly used for their smoothness and strength.
Methylhydroxyethyl cellulose (MHEC) is used to coat the interior surface of concrete pipes, giving them a uniform thickness that reduces wear over time.
This method also produces lines resistant to cracking when exposed to water, heat, or other harsh conditions.


-Food Production:
Methylhydroxyethyl cellulose (MHEC) is commonly used as an ingredient in the production of commercially-made ice cream due to its ability to stabilize the product.
Methylhydroxyethyl cellulose (MHEC) serves as an alternative to gelatin and vegetable gum such as guar gum and locust bean gum.
Methylhydroxyethyl cellulose (MHEC) is also added to baked goods, salad dressings, and salad gums.
Methylhydroxyethyl cellulose (MHEC) helps prevent sugar crystallization and increases the shelf life of food products by controlling moisture content.


-Uses of Methylhydroxyethyl cellulose (MHEC):
*Construction: Cement mortar, Concrete mix , Gypsum-based hand and machine plasters
*Painting: Latex paint, polymer emulsified, Thickening, water retention, retarding Interior paints Exterior paints
*Silicone resin-based paints, Jamb mortars Papermaking: Sizing agent, Thickener, water-retaining
*Cosmetics: Toothpaste, shampoo, Detergent, Thickener, stabilizer
*Petroleum Oil: Widely used in well drilling, filling liquids, Water retention, Thickening, Liquid loss control industrial applications


-Applications of Methylhydroxyethyl cellulose (MHEC):
*Adhesives
*Binders
*Coatings
*Construction


-Cement:
Methylhydroxyethyl cellulose (MHEC) helps increase the efficiency of cement by prolonging water retention and hydration reactions.
This helps reduce the amount of glue required during construction projects, ultimately lowering costs.
Methylhydroxyethyl cellulose (MHEC) can also be added to concrete mixes to improve their structural properties, such as flexural strength, compressive strength, and tensile strength.


-Oil drilling:
Methylhydroxyethyl cellulose (MHEC) uses is also used in oil drilling operations to thicken liquids used in the exploration process.
This helps ensure that Methylhydroxyethyl cellulose (MHEC) can be pumped through pipes without dripping or spilling, making them less effective at their intended function.


-Cosmetics:
Methylhydroxyethyl cellulose (MHEC) is found in many cosmetic products, including hair sprays, shampoos, conditioners, toothpaste, and soaps.
Like other uses for methyl hydroxyethyl cellulose, Methylhydroxyethyl cellulose (MHEC)'s used to increase the viscosity of these products and make them easier to apply.


-Paints and coatings:
Methylhydroxyethyl cellulose (MHEC), also known as MHEC and Methylcellulose, is a thickening agent used in paints and coatings.
Methylhydroxyethyl cellulose (MHEC) can help prevent paint from sagging and dripping when it dries.
The combination can also help provide the color with extra adhesion, making Methylhydroxyethyl cellulose (MHEC) helpful in constructing buildings.
Methylhydroxyethyl cellulose (MHEC) is commonly used as a thickening agent in decorative paints.
Decorative paints are not as strong as structural paints, so they need thickening agents to help them adhere to walls and other surfaces without breaking apart or peeling away.
Methylhydroxyethyl cellulose (MHEC) provides water resistance to decorative paints, making it more difficult for walls to become damaged by exposure to water.
Methylhydroxyethyl cellulose (MHEC) also helps make paint that has been applied easier to clean.


-Cement plaster:
Methylhydroxyethyl cellulose (MHEC) improve homogeneity, make the mortar more easily coated, and improve the anti-sagging ability.
Methylhydroxyethyl cellulose (MHEC) enhance liquidity and pumpability, thus improving working efficiency.
High water retention, prolong the working time of mortar, improve work efficiency, and facilitate the formation of high mechanical strength during solidification period.
Control the infiltration of air, thus eliminating the microcracks of the coating and forming the ideal smooth surface.


-Gypsum plaster:
Methylhydroxyethyl cellulose (MHEC) improve homogeneity, make the mortar more easily coated, and improve the anti-sagging ability to enhance the mobility and pumpability.
Thus, the work efficiency is improved.
High water retention, longer working time of mortar, and high mechanical strength during solidification.
A high quality surface coating is formed by controlling the consistency of the mortar.


-Masonry mortar:
Strengthen the adhesion of the surface of the masonry, and enhance the water retention, so as to improve the strength of mortar.
Improve the lubrication and plasticity so as to improve the construction performance, and use the mortar made of “guaranteed” cellulose ether to make it easier to apply and save time, and improve the cost-effectiveness.

The model with special high water retention can be used for high absorbent bricks.
Methylhydroxyethyl cellulose (MHEC) is used to fill the material.
Excellent water retention, Methylhydroxyethyl cellulose (MHEC) can prolong cooling time and improve working efficiency.

Methylhydroxyethyl cellulose (MHEC)has high lubricity, make use easier, smooth.
Methylhydroxyethyl cellulose (MHEC) improves the anti-contractility and crack resistance and improve the surface quality.
Methylhydroxyethyl cellulose (MHEC) provides smooth and uniform texture, and make the joint surface more cohesive.


-Tile adhesive:
Methylhydroxyethyl cellulose (MHEC) makes the dry mixing ingredients easy to mix, and will not produce a mass, thus saving working time.
As the application is faster and more effective, Methylhydroxyethyl cellulose (MHEC) can improve the construction and reduce the cost.
Methylhydroxyethyl cellulose (MHEC) improve the efficiency of tiling by lengthening the cooling time. Provides excellent adhesion effect.
Special development model with high anti-skid resistance can be provided.
Self-leveling the ground material.



PHYSICAL PROPERTIES OF METHYLHYDROXYETHYL CELLULOSE (MHEC):
Methylhydroxyethyl cellulose (MHEC) appears to be white powder and is odorless and tasteless.
Methylhydroxyethyl cellulose (MHEC) is featured by hygroscopicity and hardly soluble in hot water, acetone, ethanol and toluene.
In cold water Methylhydroxyethyl cellulose (MHEC) will swell into colloidal solution and its solybility is not influenced by PH value.
Similar to methyl cellulose while being added to Hdroxyethyl groups.
Methylhydroxyethyl cellulose (MHEC) is more resistant to saline, easily soluble in water and has higher gel temperature.



PROPERTIES OF METHYLHYDROXYETHYL CELLULOSE (MHEC):
● Good thickening / thickening efficiency
● Available in a wide range of molecular weight and viscosity
● Excellent properties as a water-retaining agent
● Excellent resistance to dissolved inorganic salts
● Excellent solution clarity
● Low toxicity and environmental protection



KEY PROPERTIES OF METHYLHYDROXYETHYL CELLULOSE (MHEC):
- Improves workability
- Reduce water absorption
- Increase adhesion strength



WHY METHYLHYDROXYETHYL CELLULOSE (MHEC) IS BEING PREFERRED OVER HPMC FOR CELLULOSE ETHER?
Cellulose Ether is derived from Cellulose and is a water-soluble compound used in several industries.
It finds its usage mainly in the construction, food, pharmaceutical, and cosmetics industries.
Specifically, Cellulose Ether is primarily used in the construction sector as it acts as a binder, thickener, and water retention agent in construction.

There are different grades of Cellulose Ether, which have their applicability and properties.
The two primary grades of Cellulose Ether HPMC (Hydroxypropyl Methyl Cellulose) and Methylhydroxyethyl cellulose (MHEC) have varied similarities, yet one is more preferred than the other in recent days.

Nowadays, Methylhydroxyethyl cellulose (MHEC) grade of Cellulose Ether is more preferred than the HPMC grade in the construction industry.
Though, both are being utilized widely for increasing bond strength and water retention capacity of a dry mixture of cement and gypsum, few properties differentiate them.
The first property differentiating Methylhydroxyethyl cellulose (MHEC) from HPMC is gel temperature; the gel temperature of MHEC is higher than that of Methylhydroxyethyl cellulose (MHEC).

The gel temperature of HPMC is around 60°c - 70°c, which varies as per its content and production technique; however, the gel temperature of Methylhydroxyethyl cellulose (MHEC) is generally more than 80°C, which makes it a better alternative.
Methylhydroxyethyl cellulose (MHEC) has better thermal stability owing to its high gel temperature, causing better water retention capacity during summers in South Asian Countries.

Furthermore, Methylhydroxyethyl cellulose (MHEC) has a more significant number of Hydrophilic groups in its structure, eventually leading to more hydrophilicity than the HPMC grade.
Having more Hydrophilic groups makes Methylhydroxyethyl cellulose (MHEC) better in water retention, and hence it is preferred more.
In addition, the prices of Methylhydroxyethyl cellulose (MHEC) grades have been lesser than that of HPMC, making them more economical to use.
In India, the prices of Cellulose Ether, with respective to all grades, have been marginally increasing from the first week of April.

According to ChemAnalyst, “Methylhydroxyethyl cellulose (MHEC)grade would be chosen over HPMC grade in countries including India as summers have already approached.
Construction industries would go for having cellulose ether with higher gel temperature and better hydrophilicity.
Furthermore, the Indian domestic market of Cellulose Ether is most likely to showcase stagnant to a marginal rise in the prices.”



WHAT IS THE DIFFERENCE BETWEEN HPMC AND METHYLHYDROXYETHYL CELLULOSE (MHEC)?
HPMC and Methylhydroxyethyl cellulose (MHEC) are modified cellulose forms that are mainly used as gelling agents for thickening properties in different items.
The key difference between HPMC and Methylhydroxyethyl cellulose (MHEC) is that the gel temperature of HPMC is around 60 – 75 ℃ depending on the group content and different production techniques, whereas the gel temperature of MHEC is usually higher than 80 ℃.



PHYSICAL and CHEMICAL PROPERTIES of METHYLHYDROXYETHYL CELLULOSE (MHEC):
Molecular Weight: 858.9
Hydrogen Bond Donor Count: 10
Hydrogen Bond Acceptor Count: 24
Rotatable Bond Count: 17
Exact Mass: 858.39440297
Monoisotopic Mass: 858.39440297
Topological Polar Surface Area: 332 Ų
Heavy Atom Count: 58
Formal Charge: 0
Complexity: 884
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 20
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Appearance: White powder
Loss on drying: ≤5%
PH: 4.0-8.0



FIRST AID MEASURES of METHYLHYDROXYETHYL CELLULOSE (MHEC):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated lothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of METHYLHYDROXYETHYL CELLULOSE (MHEC):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of METHYLHYDROXYETHYL CELLULOSE (MHEC):
-Extinguishing media:
*Suitable extinguishing media:
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of METHYLHYDROXYETHYL CELLULOSE (MHEC):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 240 min
*Body Protection:
Flame retardant antistatic protective clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of METHYLHYDROXYETHYL CELLULOSE (MHEC):
-Precautions for safe handling:
*Advice on protection against fire and explosion:
Take precautionary measures against static discharge.
*Hygiene measures:
Change contaminated clothing.
Preventive skin protection recommended.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of METHYLHYDROXYETHYL CELLULOSE (MHEC):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available



SYNONYMS:
2-hydroxyethyl methyl cellulose
Cellulose, 2-hydroxyethyl methyl ether
Methyl hydroxyethyl cellulose
9032-42-2
methyl 2-hydroxyethyl cellulose
ethane-1,2-diol
(2S,3R,4R,5S,6R)-2-(hydroxymethyl)-6-[(2S,3R,4S,5S,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
(2S,3S,4R,5S,6S)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2R,3S,4R,5S,6S)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane

METHYLHYDROXYETHYL CELLULOSE (MHEC)


Methylhydroxyethyl cellulose (MHEC) is a chemical compound derived from cellulose, a natural polymer found in plants.
Methylhydroxyethyl cellulose (MHEC) is a cellulose ether, which means it is a modified form of cellulose obtained by chemical reactions.
Methylhydroxyethyl cellulose (MHEC) is commonly used as a thickening agent, stabilizer, and water retention agent in various industries, including construction, pharmaceuticals, cosmetics, and food.

CAS Number: 9032-42-2
EC Number: 618-391-6

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APPLICATIONS


Methylhydroxyethyl cellulose (MHEC) is commonly used as a thickening agent in construction materials.
Methylhydroxyethyl cellulose (MHEC) is added to cement-based products such as mortars, grouts, and tile adhesives to improve their consistency and workability.
Methylhydroxyethyl cellulose (MHEC) enhances the adhesion of construction materials to substrates, ensuring better bonding.

Methylhydroxyethyl cellulose (MHEC) acts as a water retention agent, preventing premature drying and improving the curing process of cementitious formulations.
In pharmaceuticals, MHEC is utilized as a binder and viscosity modifier in tablet formulations.
Methylhydroxyethyl cellulose (MHEC) helps control the release of active ingredients and ensures uniform drug distribution.

Methylhydroxyethyl cellulose (MHEC) is used in ophthalmic solutions to increase viscosity and improve ocular contact time.
In cosmetics and personal care products, MHEC serves as a thickener and stabilizer in creams, lotions, and shampoos.
Methylhydroxyethyl cellulose (MHEC) enhances the texture and appearance of cosmetic formulations and improves their spreadability.

Methylhydroxyethyl cellulose (MHEC) is employed in food products as a thickener, stabilizer, and emulsifier.
Methylhydroxyethyl cellulose (MHEC) enhances the texture and consistency of sauces, dressings, and desserts.
In paints and coatings, MHEC is added to improve viscosity, flow, and leveling.
Methylhydroxyethyl cellulose (MHEC) acts as a rheology modifier, preventing sagging and improving paint film formation.

Methylhydroxyethyl cellulose (MHEC) is used in adhesive formulations to improve tackiness and bonding strength.
Methylhydroxyethyl cellulose (MHEC) is added to wallpaper pastes, wood glues, and other adhesives for better adhesion.
In detergents and cleaning products, MHEC functions as a thickener and stabilizer.
Methylhydroxyethyl cellulose (MHEC) improves the viscosity and suspension properties of liquid and gel formulations.
MHEC is utilized in drilling fluids for oil and gas exploration as a viscosifier and fluid loss control agent.

In textile printing, MHEC is used as a thickener and binder in dye pastes and printing inks.
Methylhydroxyethyl cellulose (MHEC) ensures sharp printing definition and prevents bleeding of colors.
MHEC is employed in ceramic processing as a binder and rheology modifier in ceramic slurries.

Methylhydroxyethyl cellulose (MHEC) improves the green strength and shape retention of ceramic bodies during forming and drying.
In paper coatings, MHEC is added to improve surface smoothness and ink receptivity.
Methylhydroxyethyl cellulose (MHEC) enhances print quality and reduces ink absorption into the paper substrate.
Overall, Methylhydroxyethyl cellulose (MHEC) finds extensive use across various industries for its versatility and performance-enhancing properties.

Methylhydroxyethyl cellulose (MHEC) is utilized in the formulation of drilling muds for the oil and gas industry to provide viscosity control and fluid loss prevention.
In the production of ceramics, MHEC serves as a binder and plasticizer in clay bodies to improve molding and shaping properties.
Methylhydroxyethyl cellulose (MHEC) is added to detergents and cleaning products to thicken solutions and enhance their stability during storage.

Methylhydroxyethyl cellulose (MHEC) is used in air fresheners, fabric softeners, and dishwashing detergents to improve the overall performance of the products.
In the agricultural sector, MHEC is utilized as a thickening agent and adhesion promoter in crop protection formulations such as herbicides and pesticides.
Methylhydroxyethyl cellulose (MHEC) helps improve the sprayability and adherence of the active ingredients to plant surfaces.

Methylhydroxyethyl cellulose (MHEC) is incorporated into fire-retardant coatings and intumescent paints to enhance their fire resistance properties.
Methylhydroxyethyl cellulose (MHEC) forms a protective barrier when exposed to fire, delaying the spread of flames and reducing smoke emissions.
In the manufacturing of batteries, MHEC is used as a binder and thickener in electrolyte pastes for improved conductivity and stability.
Methylhydroxyethyl cellulose (MHEC) is added to ceramic glazes and enamels to adjust viscosity and improve their application properties.

Methylhydroxyethyl cellulose (MHEC) ensures even coating distribution and prevents drips and runs during firing.
In the production of textile printing pastes, MHEC acts as a thickener and rheology modifier to achieve precise printing results.
Methylhydroxyethyl cellulose (MHEC) helps control ink flow and prevents smudging or bleeding of printed designs.
Methylhydroxyethyl cellulose (MHEC) is used in the formulation of polymer dispersions and latex paints as a thickener and stabilizer.

Methylhydroxyethyl cellulose (MHEC) enhances the storage stability and application properties of water-based coatings.
In the manufacturing of asphalt emulsions, MHEC is added as a stabilizer and viscosity modifier to improve mix uniformity and coating durability.
Methylhydroxyethyl cellulose (MHEC) is employed in the production of ceramic membranes for water filtration applications as a binder and pore former.
Methylhydroxyethyl cellulose (MHEC) helps control pore size distribution and improves the filtration efficiency of the membranes.

In the formulation of personal care products such as toothpaste and mouthwash, MHEC acts as a thickener and binder to improve product texture and stability.
Methylhydroxyethyl cellulose (MHEC) is added to hair care products such as styling gels and mousses to provide hold and shape retention.
In the pharmaceutical industry, MHEC is used in controlled-release drug delivery systems to regulate drug release kinetics.
Methylhydroxyethyl cellulose (MHEC) ensures consistent and prolonged release of active ingredients for optimized therapeutic effects.

Methylhydroxyethyl cellulose (MHEC) is employed in the production of ceramic membranes for water treatment applications to remove contaminants and impurities from water sources.
Methylhydroxyethyl cellulose (MHEC) plays a crucial role in improving the efficiency and reliability of water purification processes.
Overall, Methylhydroxyethyl cellulose (MHEC) finds diverse applications across numerous industries due to its versatile properties and compatibility with various formulations and materials.

Methylhydroxyethyl cellulose (MHEC) is used in the formulation of polymer-modified bitumen for road construction applications to enhance durability and performance.
Methylhydroxyethyl cellulose (MHEC) improves the cohesion and adhesion properties of bituminous binders, reducing rutting and cracking.
In the production of fiberglass-reinforced plastics (FRP), MHEC serves as a binder and rheology modifier to improve resin flow and wetting of fibers.

Methylhydroxyethyl cellulose (MHEC) ensures uniform distribution of resin and reinforcement, enhancing the strength and structural integrity of FRP components.
In the agricultural industry, MHEC is added to seed coatings and fertilizers to improve adhesion and release properties.
Methylhydroxyethyl cellulose (MHEC) enhances the dispersibility and effectiveness of agricultural inputs, promoting uniform crop growth and yield.
Methylhydroxyethyl cellulose (MHEC) is used in the formulation of printing inks for packaging and labeling applications to improve print quality and adhesion to substrates.

Methylhydroxyethyl cellulose (MHEC) ensures sharp and vibrant printing results, even on challenging surfaces.
In the production of decorative coatings and textured finishes, MHEC serves as a thickener and rheology modifier to achieve desired aesthetics and surface effects.
Methylhydroxyethyl cellulose (MHEC) imparts body and consistency to coatings, facilitating application and enhancing surface texture.

Methylhydroxyethyl cellulose (MHEC) is employed in the manufacturing of textile sizing agents to improve fiber-to-fiber adhesion and reduce yarn breakage during weaving.
Methylhydroxyethyl cellulose (MHEC) enhances the strength and dimensional stability of woven fabrics, resulting in higher productivity and quality.
In the formulation of metalworking fluids, MHEC acts as a thickener and lubricity enhancer to improve machining performance and tool life.

Methylhydroxyethyl cellulose (MHEC) provides excellent boundary lubrication and chip evacuation, reducing friction and heat generation during metal cutting operations.
Methylhydroxyethyl cellulose (MHEC) is added to drilling fluids for geotechnical and environmental drilling applications to improve hole stability and borehole integrity.
Methylhydroxyethyl cellulose (MHEC) helps control fluid loss and filter cake formation, ensuring efficient drilling operations and environmental protection.

In the production of polymer dispersions for coatings and adhesives, MHEC serves as a thickener and stabilizer to improve formulation consistency and storage stability.
Methylhydroxyethyl cellulose (MHEC) enhances the film-forming properties and adhesion of water-based polymer coatings, ensuring long-lasting performance and durability.
Methylhydroxyethyl cellulose (MHEC) is utilized in the formulation of industrial cleaners and degreasers as a thickener and suspending agent to improve product stability and cleaning effectiveness.
Methylhydroxyethyl cellulose (MHEC) helps suspend and disperse soil and contaminants, facilitating their removal from surfaces.
In the manufacturing of industrial ceramics, MHEC is used as a binder and plasticizer to improve green strength and moldability of ceramic bodies.

Methylhydroxyethyl cellulose (MHEC) ensures uniform particle distribution and enhances the shaping and drying characteristics of ceramic compositions.
Methylhydroxyethyl cellulose (MHEC) is added to gypsum-based products such as plasters and joint compounds to improve workability, sag resistance, and surface finish.
Methylhydroxyethyl cellulose (MHEC) enhances the cohesiveness and smoothness of gypsum formulations, reducing cracking and improving aesthetic appeal.
Overall, Methylhydroxyethyl cellulose (MHEC) continues to find diverse applications across a wide range of industries, contributing to improved performance, efficiency, and quality of various products and processes.



DESCRIPTION


Methylhydroxyethyl cellulose (MHEC) is a chemical compound derived from cellulose, a natural polymer found in plants.
Methylhydroxyethyl cellulose (MHEC) is a cellulose ether, which means it is a modified form of cellulose obtained by chemical reactions.
Methylhydroxyethyl cellulose (MHEC) is commonly used as a thickening agent, stabilizer, and water retention agent in various industries, including construction, pharmaceuticals, cosmetics, and food.

Methylhydroxyethyl cellulose (MHEC) is synthesized through the reaction of cellulose with methyl chloride and ethylene oxide, resulting in the introduction of methyl and hydroxyethyl groups onto the cellulose backbone.
This modification enhances the water solubility and rheological properties of cellulose, making MHEC suitable for a wide range of applications.

In the construction industry, MHEC is commonly used as a thickener and water retention agent in cement-based products such as mortars, grouts, tile adhesives, and self-leveling compounds.
Methylhydroxyethyl cellulose (MHEC) improves the workability, consistency, and open time of these materials, allowing for easier application and better performance.

In pharmaceutical formulations, MHEC is used as a binder, film former, and viscosity modifier in tablet coatings, suspensions, and ophthalmic solutions.
Methylhydroxyethyl cellulose (MHEC) helps control the release of active ingredients, improve drug stability, and enhance the texture and appearance of dosage forms.

In cosmetics and personal care products, MHEC is employed as a thickener, emulsifier, and stabilizer in creams, lotions, shampoos, and other formulations.
Methylhydroxyethyl cellulose (MHEC) provides smooth texture, uniform consistency, and improved stability to these products.

Methylhydroxyethyl cellulose (MHEC) is a versatile cellulose ether widely used in various industries.
Methylhydroxyethyl cellulose (MHEC) is derived from natural cellulose through chemical modification processes.
Methylhydroxyethyl cellulose (MHEC) is a white to off-white, odorless powder with excellent water solubility.

Methylhydroxyethyl cellulose (MHEC) forms transparent and viscous solutions when dissolved in water.
Methylhydroxyethyl cellulose (MHEC) is valued for its thickening, stabilizing, and film-forming properties.

Methylhydroxyethyl cellulose (MHEC) is commonly employed as a thickener and rheology modifier in construction materials.
Methylhydroxyethyl cellulose (MHEC) improves the workability and consistency of cement-based products such as mortars and grouts.
Methylhydroxyethyl cellulose (MHEC) enhances the adhesion, cohesion, and open time of construction formulations.
Methylhydroxyethyl cellulose (MHEC) also acts as a water retention agent, reducing water loss during the curing process.
In pharmaceutical formulations, MHEC serves as a binder and film former in tablet coatings.

Methylhydroxyethyl cellulose (MHEC) controls the release of active ingredients and improves the appearance of dosage forms.
Methylhydroxyethyl cellulose (MHEC) is used in ophthalmic solutions to increase viscosity and prolong ocular contact time.
In cosmetics and personal care products, MHEC functions as a thickener and stabilizer.

Methylhydroxyethyl cellulose (MHEC) imparts smooth texture and uniform consistency to creams, lotions, and shampoos.
Methylhydroxyethyl cellulose (MHEC) enhances the spreadability and moisturizing properties of cosmetic formulations.
In food applications, MHEC acts as a thickener, stabilizer, and emulsifier.

Methylhydroxyethyl cellulose (MHEC) improves the texture, mouthfeel, and shelf life of food products such as sauces and dressings.
Methylhydroxyethyl cellulose (MHEC) is compatible with a wide range of other ingredients and additives.
Methylhydroxyethyl cellulose (MHEC) exhibits excellent compatibility with other polymers, surfactants, and preservatives.

Methylhydroxyethyl cellulose (MHEC) is non-ionic and therefore compatible with both cationic and anionic compounds.
Methylhydroxyethyl cellulose (MHEC) is stable over a wide pH range and in the presence of salts and oxidizing agents.
Methylhydroxyethyl cellulose (MHEC) is biodegradable and environmentally friendly, with low toxicity and eco-toxicity.

Methylhydroxyethyl cellulose (MHEC) undergoes controlled degradation in soil and water without causing harm to ecosystems.
Methylhydroxyethyl cellulose (MHEC) is manufactured under strict quality control standards to ensure consistency and purity.
Overall, Methylhydroxyethyl cellulose (MHEC) is a valuable additive that enhances the performance and functionality of various products across multiple industries.



PROPERTIES


Chemical Formula: Variable, depending on the degree of substitution and molecular weight.
Molecular Weight: Variable, depending on the degree of polymerization and substitution.
Content of Hydroxyethyl: 4%-12%
Content of Methoxy: 21%-31%
Ash Content: 2%-3%
Moisture: ≤5%
PH Value: 5-8.5
Gel Temperature: 65℃ -75℃
Water Retention: 90% - 98%
Viscosity(NDJ-1): 10,000-200,000 Mpas
Viscosity(Brookfield): 40000-85000 Mpas



FIRST AID


Inhalation:

If inhaled, remove the affected individual to fresh air immediately.
Assist the person in finding a comfortable position and encourage deep breathing.
If breathing difficulties persist or if the person is unconscious, seek medical attention immediately.
Provide artificial respiration if the person has stopped breathing but is still responsive.
Keep the affected person warm and calm while awaiting medical assistance.


Skin Contact:

Remove contaminated clothing and shoes immediately.
Wash the affected skin area with soap and water thoroughly for at least 15 minutes.
If irritation or redness develops, seek medical attention.
If skin irritation persists, apply a soothing cream or lotion to alleviate discomfort.
Rinse contaminated clothing and shoes thoroughly before reuse.


Eye Contact:

Flush the eyes with gently flowing lukewarm water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.
Remove contact lenses if present and easily removable after the initial flushing.
Seek immediate medical attention, even if there are no signs of discomfort or irritation.
Protect the unaffected eye from contamination while rinsing the affected eye.
Do not rub the eyes, as it may exacerbate irritation or injury.


Ingestion:

If swallowed accidentally, do not induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth thoroughly with water to remove any residual chemical.
Do not give anything by mouth to an unconscious person.
Seek immediate medical attention or contact a poison control center for further guidance.
Provide medical personnel with information about the ingested amount and time of exposure.


General Measures:

Move the affected person to a well-ventilated area and provide fresh air.
Keep the person warm and calm, reassuring them while administering first aid.
Monitor vital signs such as breathing, pulse, and consciousness level.
Do not leave the affected person unattended, especially if they are experiencing symptoms.
If necessary, provide supportive measures such as oxygen therapy or cardiopulmonary resuscitation (CPR) according to trained personnel's instructions.


Medical Attention:

If symptoms persist or worsen after initial first aid measures, seek medical attention promptly.
Provide medical personnel with safety data sheets (SDS) or other relevant information about the chemical for proper treatment.
Follow any additional instructions or recommendations provided by medical professionals.
Keep the affected person under medical observation for any delayed or secondary effects.
Inform medical personnel of any pre-existing medical conditions or allergies that may affect treatment options.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including chemical-resistant gloves, safety goggles or face shield, and protective clothing, when handling Methylhydroxyethyl cellulose (MHEC).
Use respiratory protection, such as a dust mask or respirator, if there is a risk of inhalation of airborne particles.

Ventilation:
Work in a well-ventilated area or use local exhaust ventilation to control airborne concentrations of dust or aerosols.
Avoid creating dust clouds by using handling techniques that minimize the generation of airborne particles.

Avoidance of Contact:
Avoid skin contact and inhalation of MHEC dust or aerosols.
Use appropriate handling procedures, such as scoops or dust masks, to minimize exposure during transfer or mixing operations.
Do not eat, drink, or smoke while handling MHEC, and wash hands thoroughly after handling to prevent accidental ingestion.

Spill and Leak Procedures:
Clean up spills immediately to prevent accidental exposure and environmental contamination.
Use absorbent materials, such as vermiculite or sand, to contain and absorb spilled material.
Avoid sweeping or blowing dust, as it may become airborne and spread contamination.
Dispose of contaminated materials according to local regulations and guidelines.


Storage:

Container Selection:
Store Methylhydroxyethyl cellulose (MHEC) in tightly sealed containers made of compatible materials, such as high-density polyethylene (HDPE) or glass.
Ensure containers are labeled with the appropriate hazard warnings and handling instructions.

Temperature and Humidity:
Store MHEC in a cool, dry, and well-ventilated area away from direct sunlight and heat sources.
Avoid exposure to high temperatures or humidity, as it may affect the stability and performance of the product.

Compatibility:
Keep MHEC away from incompatible materials, including strong acids, bases, oxidizing agents, and reducing agents.
Store away from sources of ignition or heat to prevent the risk of fire or spontaneous combustion.

Segregation:
Segregate MHEC from food, beverages, and animal feed to prevent contamination.
Store away from sources of contamination, such as pesticides, fertilizers, or other chemicals.

Handling Practices:
Use appropriate handling equipment, such as scoops or funneling devices, to transfer MHEC between containers.
Avoid generating dust or aerosols during handling by minimizing agitation or mechanical stress.
Use caution when opening containers to prevent sudden release of dust or vapors.


Emergency Procedures:

Spills and Releases:
In case of a spill or release, evacuate the area and restrict access to prevent exposure to unprotected individuals.
Notify appropriate personnel, such as supervisors or emergency responders, and follow established spill response procedures.
Wear appropriate PPE, including respiratory protection, when cleaning up spills to avoid inhalation or skin contact.

First Aid:
In the event of exposure, follow the recommended first aid measures outlined in the safety data sheet (SDS) or product label.
Seek medical attention for individuals exposed to significant quantities or experiencing adverse effects.
Provide medical personnel with information about the chemical and exposure route for appropriate treatment.

METHYLISOTHIAZOLINE
Methyl-4-iso;Isothiazolone 14%;METHYLISOTHIAZOLIN; METHYLISOTHIAZOLINE; METHYLISOTHIAZOLONE; METHYLISOTHIAZDINONE; CAS No:2682-20-4
METHYLISOTHIAZOLINONE
Methylisothiazolinone is a chemical substance that is effective in eliminating and controlling the growth of potentially harmful bacteria.
Methylisothiazolinone, MIT, or MI, is the organic compound with the formula S(CH)2C(O)NCH3.
Methylisothiazolinone is a white solid.


CAS Number: 2682-20-4
EC Number: 220-239-6
Chem/IUPAC Name: 2-Methyl-2H-isothiazol-3-one
Chemical formula: C4H5NOS


Methylisothiazolinone is a preservative.
Methylisothiazolinone is a common preservative used in the personal care industry.
Methylisothiazolinone is a clear, colourless liquid that is soluble in water.


Methylisothiazolinone is a preservative commonly used in water-based personal care products.
Methylisothiazolinone is a powerful synthetic biocide and preservative within the group of isothiazolinones.
Methylisothiazolinone has the chemical formula C4H5NOS.


Methylisothiazolinone is a synthetic chemical used for controlling microbial growth in water-containing solutions.
Any product that contains water is particularly susceptible to being spoiled by microbial growth, causing problems such as discoloration, unpleasant odors or breakdown.


Methylisothiazolinone is a chemical substance that is effective in eliminating and controlling the growth of potentially harmful bacteria.
Under certain conditions, microorganisms can even grow to potentially harmful levels.
Preservatives are designed to help prevent these problems.


Methylisothiazolinone is only one of a very limited number of broad spectrum preservatives - meaning it is effective against a variety of bacteria, yeasts and molds.
Methylisothiazolinone is an isothiazolinone based biocide and preservative used in personal care products.


Methylisothiazolinone and Methylchloroisothiazolinone were very common preservatives found in many liquid personal care and leave-in products throughout the 1980's and 90's - Shampoo, conditioner, hair color, body wash, lotion, sunscreen, mascara, shaving cream, baby lotion, baby shampoo, hairspray, makeup remover, liquid soaps and detergents.


Methylisothiazolinone - also known as MI - is a synthetic preservative used in many consumer products, including cosmetics, pharmaceutical products and household cleansers, as well as industrial products and settings like jet fuels, printing inks and cooling tower water.



USES and APPLICATIONS of METHYLISOTHIAZOLINONE:
Isothiazolinones, a class of heterocycles, are used as biocides in numerous personal care products and other industrial applications.
Methylisothiazolinone and related compounds have attracted much attention for their allergenic properties, e.g. contact dermatitis.
Methylisothiazolinone is used for controlling microbial growth in water-containing solutions.


Methylisothiazolinone is typically used in a formulation with 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT), in a 3:1 mixture (CMIT:MIT).
Methylisothiazolinone also has been used to control slime in the manufacture of paper products that contact food.
In addition, Methylisothiazolinone serves as an antimicrobial agent in latex adhesives and in paper coatings that also contact food.


Methylisothiazolinone is used to control slime-forming bacteria, fungi,
and algae in pulp/paper mills, cooling water systems, oil field operations, industrial process waters, and air washer systems and is incorporated into adhesives, coatings, fuels, metal working fluids, resin emulsions, paints, and various other speciality industrial products as a preservative.


Methylisothiazolinone is also used to control the growth of mold, mildew, and sapstain on wood products.
Formulations include soluble concentrated liquids and soluble concentrated solids.
Products containing Methylisothiazolinone are added to systems and industrial products using manual pouring and metered pumping methods, dip tanks and sprayers.


Methylisothiazolinone is a widely-used preservative; has been associated with allergic reactions.
Lab studies on the brain cells of mammals also suggest that Methylisothiazolinone may be neurotoxic.
Methylisothiazolinone is a widely used antiseptic, which can effectively kill algae, bacteria and fungi.


The active monomer, Methylisothiazolinone, can be widely used in industrial cooling water, oil field return tank water, paper industry, pipeline, coating, paint, rubber, cosmetics, photographic film and washing products and other industries.
Methylisothiazolinone can effectively kill a variety of bacteria at low concentrations, especially for the preservation of cosmetics and personal care products.


Methylisothiazolinone enhances the safety and shelf-life of products by preventing the growth of bacteria and yeasts.
Without preservatives like Methylisothiazolinone, products could start to smell unpleasant, change colour or grow moulds which can produce toxins which are harmful to health.


Methylisothiazolinone (MI) is a preservative that' super efficient against bacteria at surprisingly low concentrations.
Methylisothiazolinone is a preservative that is found in a wide array of liquid cosmetics, personal care products and cleaning products on the market today.
Methylisothiazolinone's function is to inhibit the growth of bacteria.


Methylisothiazolinone, along with other isothiazolinones, is a biocide widely used as a preservative in personal care products.
Methylisothiazolinone is also used in many industrial processes, such as paint and paper manufacturing, metalworking, mining, and sanitizing.
Methylisothiazolinone was initially used occupationally, in paints, adhesives/glues and cleaners etc, as a mixture with methylchloroisothiazolinone (MCI).


Since 2005, Methylisothiazolinone has been widely used in cosmetics and household products, such as moist wipes, shampoos, cleaners and liquid laundry products.
Methylisothiazolinone is a preservative that’s active against bacteria, yeast, and fungi.


Methylisothiazolinone’s used in the manufacture of water-based cosmetics and personal care products.
Methylisothiazolinone’s also used in industrial processes, including the manufacture of paper coatings, detergents, paints, glue, cutting oils
Methylisothiazolinone, better known by the acronym MIT, is used as a synthetic preservative in cosmetics.


Methylisothiazolinone is mostly used with CMIT (Methylchloroisothiazolinone).
Methylisothiazolinone can be used by all hair types.
Methylisothiazolinone is more important to be conscious of any allergies or skin you might have before using products containing the ingredient.


Methylisothiazolinone or MIT is a preservative used in many consumer goods including cosmetic products, to preserve product quality and ensure consumer safety by preventing the growth of microbes.
Methylisothiazolinone is used to protect products from contamination by potentially pathogenic microbes (fungi and bacteria).


Methylisothiazolinone's use allows to ensure the product is safe for consumers.
Preservatives that are generally recommended for use only in rinse-off products such as cleansers or shampoos.
Methylisothiazolinone is known to be sensitizing when used in leave-on products.


Methylisothiazolinone is used paints, glues and cooling lubricants, household and industrial cleaning agents, stationery, lubricants, wood care and water treatment agents.
Methylisothiazolinone is a widely used preservative and biocide.


Methylisothiazolinone is used Baby care - lotions, wipes, diaper cream, bubble bath, shampoo, soap.
Methylisothiazolinone is used Industrial products, All purpose cleaner, Automatic dishwasher, Bath and shower cleaner, and Bleach products.
Methylisothiazolinone is used Building materials - adhesives, paints, resins, emulsions, Carpet care, Disinfectant, Fabric softener sheets, and Fabric treatment.


Methylisothiazolinone is used Floor care, Furniture polish, Hand dishwashing, and Household cleaner wipes.
Methylisothiazolinone is used Kitchen cleaners, Laundry detergent, Lice treatment, Metal cleaner, and Metal working fluids.
Methylisothiazolinone is used Oil controller, Oil field operations, Paper mills, Stain remover, and Surface cleaner.


Methylisothiazolinone is used Make-ups, Moisturizers, Nail Polish / Nail Polish Remover, Powders / Sprays, Shampoos / Conditioners, Shaving products, Soaps / Cleansers, Sunscreens and Self-Tanners, and Spermacides.
You will often see methylisothiazolinone mixed with methylchloroisothiazolinone (MCI) to make a particularly effective isothiazolinone preservative.


Methylisothiazolinone is a common preservative used in house cleaning supplies and personal care products, including makeup, lotions, shampoos, conditioners, dish soaps, laundry detergents, and more.
Methylisothiazolinone is also sometimes used for industrial purposes in painting, manufacturing, metalworking, mining, and sanitizing.


Methylisothiazolinone is also used for controlling microbial growth in water-containing solution.
Methylisothiazolinone is used Toilet bowl cleaner, Water cooling and treatment systems, Wood treatment, Skin Care Products / Cosmetics, Antiperspirants / Deodorants, Hair sprays, gels, tonics and lotions, and Hair Colorants / “Permanents-Relaxers.


Methylisothiazolinone is used to study the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites.
Methylisothiazolinone is a common preservative used in industrial products, owing to its strong biocide effect.


You can find Methylisothiazolinone in makeup items like foundation, eye shadow and mascara, as well as personal care items like moisturisers, sunscreen, lotions, gels, mouth wash, shampoos, soaps, body wash and wet wipes, including baby wipes.
Methylisothiazolinone’s also used in some over-the-counter and prescription medicines, along with household cleaning products, laundry detergents, polishes, adhesives, pesticides and so on.


Methylisothiazolinone has multiple commercial and industrial applications.
In cosmetic products, Methylisothiazolinone is most commonly used as a preservative in products such as sunscreens, shampoos, sanitary wipes, makeup and lotions.


Methylisothiazolinone’s industrial use includes energy production, metal working, and paint manufacturing.
Methylisothiazolinone is a commonly used synthetic biocide and preservative and is found in personal care and industrial applications.
Methylisothiazolinone is a preservative that can also be found in shampoos, skin care products and makeup.


Methylisothiazolinone helps maintain product quality and performance over time.
Some people raise concerns about preservatives, because a small number of individuals have allergies to them just as some people have allergies to nuts or bees.
But preservatives play a very important role in food, cosmetics and household products.


Without preservatives, many products would not last more than a week or two before being contaminated by bacteria, mold or yeast.
Methylisothiazolinone and other isothiazolinone-derived biocides are used to prevent microbial growth in liquid formulations, as such MIT is found mostly in liquid cosmetics and personal care formulations.



YOU MIGHT FIND METHYLISOTHIAZOLINONE IN:
*Shampoos and conditioners
*Hair colouring liquids
*Moisturising lotions
*Sun lotions
*Baby lotions
*Hairsprays
*Liquid soaps
*Detergents



WHAT IS METHYLISOTHIAZOLINONE USED FOR?
*Personal care products
*Makeup
*Baby hygiene products
*Sunscreens
*Liquid soaps
*Liquid laundry detergent
*Hair dye and treatments
*Some household cleaners
*Various industrial products like paint, glue, cutting oils, and paper coatings



FUNCTIONS OF METHYLISOTHIAZOLINONE:
*Preservative:
Methylisothiazolinone inhibits the development of microorganisms in cosmetic products.



MAIN BENEFITS OF METHYLISOTHIAZOLINONE:
Methylisothiazolinone prevents bacteria growth in hair products



HOW OFTEN CAN YOU USE METHYLISOTHIAZOLINONE:
Methylisothiazolinone can be used daily



WORKS WELL WITH, METHYLISOTHIAZOLINONE:
There are no known interactions with other ingredients.



WHY IS METHYLISOTHIAZOLINONE USED IN COSMETICS AND PERSONAL CARE PRODUCTS?
Methylisothiazolinone and Methylchloroisothiazolinone (MCI) are preservatives.
Preservatives are natural or man-made ingredients designed to help ensure the safety and quality of products by protecting them against the growth of microorganisms during storage and, most importantly, during use by consumers.

Any product that contains water is particularly susceptible to being spoiled by microbial growth, causing problems such as discoloration, unpleasant odors or breakdown.
Under certain conditions, microorganisms can even grow to potentially harmful levels.

Preservatives are designed to help prevent these problems.
Although Methylisothiazolinone may be used in cosmetics and personal care products alone, it is often used as a mixture with Methylchloroisothiazolinone.
In cosmetics and personal care products historically, Methylisothiazolinone, or the mixture, Methylisothiazolinone and Methylchloroisothiazolinone, was used
in various rinse-off and leave-on formulations including hair products, shampoos, skin care products, bath products, eye and facial makeup, wet wipes and suntan products.



WHAT DOES METHYLISOTHIAZOLINONE DO IN A FORMULATION?
*Preservative



BENEFITS OF METHYLISOTHIAZOLINONE FOR HAIR:
Methylisothiazolinone does not have any benefits specifically for your hair.
Methylisothiazolinone won't make it shiny, more manageable, thicker, or stronger.
Methylisothiazolinone is strictly used in cosmetics as a preservative and bacteria-inhibitor, which is obviously an important thing we all want in a product we're keeping in a warm, damp place like the bathroom.

Even though Methylisothiazolinone doesn't have direct benefits for hair, it does have a number of benefits in a product formulation.
Methylisothiazolinone protects products at a very low-use level.
Methylisothiazolinone's also water soluble, making it very easy to mix in.
Methylisothiazolinone's also stable over a broad pH range, making it suitable for many types of formulas like shampoos and conditioners.



METHYLISOTHIAZOLINONE, A CLINICIAN'S POINT OF VİEW:
Methylisothiazolinone is also used in air fresheners such as Glade Premium Room Spray, and may be a preservative component of a product.
Specifically Methylisothiazolinone can be found in cleansers such as liquid dish soap, liquid laundry soap, all purpose spray cleaners and window cleaning solutions.
Methylisothiazolinone can also be found in products labeled "natural".
Corporations trying to sell "green" (but not so green) cleaners often use Methylisothiazolinone as a preservative.



WHAT ARE METHYLISOTHIAZOLINONE and METHYLCHLOROISOTHIAZOLINONE?
Methylisothiazolinone (MIT) and Methylchloroisothiazolinone (CMIT) are widely used preservatives found in liquid cosmetic and personal care products.
Both chemicals inhibit bacterial growth in cosmetic products on their own, but they are most commonly used as a mixture in products.



HOW TO USE METHYLISOTHIAZOLINONE FOR HAIR:
Methylisothiazolinone is a preservative used in haircare products like shampoos and conditioners.
If you have a known sensitivity be sure to read ingredient statements on cosmetics and personal care products, because of the small percentages used preservatives are typically at the end of the list.
FYI, this doesn't mean that if you do happen to find Methylisothiazolinone in your haircare, that you need to toss your products.



METHYLISOTHIAZOLINONE, FOUND IN:
*Shampoo
*Conditioner
*Hair color
*Body wash
*Lotion
*Sunscreen
*Mascara
*Shaving cream
*Baby lotion
*Baby shampoo
*Hairspray
*Makeup remover
*Liquid soaps and detergents.



FUNCTIONS OF METHYLISOTHIAZOLINONE:
Methylisothiazolinone (MIT) is a new fungicide introduced from Europe.
Isothiazolinone organic compounds can inhibit the growth and reproduction of various microorganisms (such as bacteria, fungi, yeast, etc.), and are widely used broad-spectrum fungicides.
Compared with other types of fungicides, isothiazolinone fungicides have obvious effect and fast action speed in controlling the growth and metabolism of microorganisms and preventing the formation of biofilm.



WHAT ARE SOME PRODUCTS THAT MAY CONTAIN METHYLISOTHIAZOLINONE?
*Body Washes/Hand Soaps/Moisturizers
*Cleaners
*Hair Products
• Hair Dyes
• Shampoos
• Conditioners
*Paint
*Pet Care
*Yard Care Products



PREPARATION OF METHYLISOTHIAZOLINONE:
Methylisothiazolinone is prepared by cyclization of cis-N-methyl-3-thiocyanoacrylamide:
NCSCH=CHC(O)NHCH3⟶SCH=CHC(O)NCH3+HCN



WHERE IS METHYLISOTHIAZOLINONE FOUND?
Methylisothiazolinone is a preservative used in personal hygiene products (such as shampoos, lotions, emulsions, and sun screens), and in industrial cooling oils, cutting oils, and paper finishes.
Methylisothiazolinone is also commonly added to household cleaners as a substitute for formaldehyde.
Methylisothiazolinone is a component in Kathon and Grotan preservatives.



WHAT PRODUCTS IS METHYLISOTHIAZOLINONE IN?
Methylisothiazolinone is found in a multitude of products, including those claiming to be “natural”.
The list includes cleaning products, detergents, lotions, sunscreens, shampoos, conditioners, hair coloring, body washes, mascara, shaving cream, make-up remover, liquid soaps, and baby products including wipes, lotions and shampoos.



PHYSICAL and CHEMICAL PROPERTIES of METHYLISOTHIAZOLINONE:
Chemical formula: C4H5NOS
Molar mass: 115.1 g/mol
Appearance: white solid
Cas No: 2682-20-4
Molecular Formula: C4H5NOS
Molecular Weight: 115.15
Appearance: Yellowish transparent liquid
Purity(%): ≥10; 20; 50
pH value: 4.0~7.0
Density (g/ml): ≥1.02
Physical state: Powder with lumps
Color: dark yellow
Odor: No data available
Melting point/freezing point:
Melting point/range: 46,7 - 48,3 °C
Initial boiling point and boiling range: > 130 °C at 16 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: 396 °C at 1.012 hPa
Decomposition temperature: No data available
pH: 2,58 at 50 g/l at 25 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: soluble
Partition coefficient: n-octanol/water:
log Pow: -0,34 at 30 °C
Bioaccumulation is not expected.
Vapor pressure: 0,0099 hPa at 20 °C
Density: 1,39 g/cm3 at 20 °C
Relative density: 1,39 at 20 °C
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Surface tension 68,8 mN/m at 1g/l at 19,5 °C
Dissociation constant > 2,81 at 21 °C



FIRST AID MEASURES of METHYLISOTHIAZOLINONE:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
Do not attempt to neutralise.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of METHYLISOTHIAZOLINONE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of METHYLISOTHIAZOLINONE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of METHYLISOTHIAZOLINONE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Body Protection:
Acid-resistant protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of METHYLISOTHIAZOLINONE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Air sensitive.
Store under inert gas.



STABILITY and REACTIVITY of METHYLISOTHIAZOLINONE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available



SYNONYMS:
2-Methyl-1,2-thiazol-3(2H)-one
2-Methylisothiazol-3(2H)-one
2-Methyl-4-isothiazolin-3-one
Methylisothiazolinone
2-Methyl-4-Isothiazolin-3-one
2-Methyl-3-isothiazolone
2-Methylisothiazol-3-one
2-Methyl-2H-isothiazol-3-one
2-Methyl-4-isothiazolin-3-one
2-Methyl-3(2H)-isothiazolone
Methylisothiazolinone (MI, MIT)
2-Methyl-4-isothiazolin-3-one
2-Methyl-2,3-dihydroisothiazol-3-one
2-methyl- 3 (2H) -isothiazolone
2-methyl-2H-isothiazol-3-one
2-methyl-3 (2H) -isothiazolone
2-methyl-4-isothiazolin-3-one
3 (2H) -isothiazolone, 2-methyl-
3 (2H) isothiazolone, 2methyl
2-methyl-3 (2H) -isothiazolone
2-methyl-4-isothiazolin-3-one
2-methyl-4-isothiazolin-3-one
2-methyl-2H-isothiazol-3-one
2-Methylisothiazol-3(2H)-one
Neolone 950 preservative
OriStar MIT
Microcare MT
MI
MIT

METHYLISOTHIAZOLINONE
METHYLISOTHIAZOLINONE = 2-METHYL-4-ISOTHIAZOLIN-3-ONE = MI = MIT


CAS Number: 2682-20-4
EC Number: 220-239-6
MDL number: MFCD01742315
Empirical Formula (Hill Notation): C4H5NOS


Methylisothiazolinone is a clear, colourless liquid that is soluble in water.
Methylisothiazolinone enhances the safety and shelf-life of products by preventing the growth of bacteria and yeasts.
Without preservatives like Methylisothiazolinone, products could start to smell unpleasant, change colour or grow moulds which can produce toxins which are harmful to health.


Methylisothiazolinone, also known as MI, is added to substances containing water to stop the growth of microorganisms.
Methylisothiazolinone simply prevents the product from rotting and aging.
Methylisothiazolinone is commonly found in cosmetics, hygiene products, and other body care products.
Methylisothiazolinone, MIT, or MI, is the organic compound with the formula S(CH)2C(O)NCH3.


Methylisothiazolinone is a white solid.
Isothiazolinones, a class of heterocycles, are used as biocides in numerous personal care products and other industrial applications.
Methylisothiazolinone and related compounds have attracted much attention for their allergenic properties, e.g. contact dermatitis.
Methylisothiazolinone (MI) is a preservative that' super efficient against bacteria at surprisingly low concentrations.


Methylisothiazolinone is a component in Kathon and Grotan preservatives.
Methylisothiazolinone is a colorless,clear liquid with amild odor that is completely soluble in water; mostly soluble in acetonitrile, methanol, and hexane; and slightly soluble in xylene.
Methylisothiazolinoneis a heterocyclic organic compound used as a preservative in cosmetics and personal care products in concentrations up to 0.01%.
Methylisothiazolinone is a 1,2-thazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom.


Methylisothiazolinone has a role as an antifouling biocide, an antimicrobial agent and an antifungal agent.
Methylisothiazolinone is a powerful biocide.
That means Methylisothiazolinone’s a chemical substance that can control or kill harmful microorganisms.
Methylisothiazolinone works well as a preservative in products like shampoo and body care products, helping them to last a long time on the shelf and in your bathroom cabinets without becoming contaminated with unwanted bugs, bacteria, and fungi.


Methylisothiazolinone belongs to a group of similar compounds called “isothiazolinones,” which also include the following chemicals:
*Chloromethylisothiazolinone (CMIT)
*Benzisothiazolinone (BIT)
*Octylisothiazolinone (OIT)
*Dichlorooctylisothiazolinone (DCOIT)


Methylisothiazolinone (MI) is an isothiazolinone-derived biocide used for controlling microbial growth in industrial and household products, often in a mixture with 5-chloro-2-methyl-3-isothiazolone (MCI).
Methylisothiazolinone is active against Gram-positive and Gram-negative bacteria, fungi, and yeast with MIC values of 0.0045, 0.0015, >0.01, and 0.0065% (w/w) for S. aureus, P. aeruginosa, A. niger, and C. albicans, respectively, when used alone.
MIC values are 7 to 200-fold lower when Methylisothiazolinone is used in combination with MCI.


Methylisothiazolinonedecreases neurite outgrowth of rat cortical neurons when used at concentrations of 0.1-3 μM and inhibits Src family kinases in cell-free assays.
There are no known interactions with other ingredients.
Methylisothiazolinone (MIT) is a chemical substance that is effective in eliminating and controlling the growth of potentially harmful bacteria,.


Methylisothiazolinone (MI) is a preservative.
Methylisothiazolinone (also called 2-methyl-4-isothiazolin-3-one), is a powerful synthetic biocide and preservative within the group of isothiazolinones.
Methylisothiazolinone is a synthetic chemical used in consumer products for its antimicrobial properties.
Methylisothiazolinone is most often applied to cleaning products as a synthetic preservative.


Methylisothiazolinone was first used in Europe in the 1970s and the United States in the 1980s.
The original European recommendation was to use 0.003% concentration or 30 parts per million (ppm).
In 2000, companies started using methylisothiazolinone in industrial products.
By 2005 some cosmetic companies were using as much as 50 to 100 ppm.



USES and APPLICATIONS of METHYLISOTHIAZOLINONE:
Methylisothiazolinone (MCI) is a preservative that’s active against bacteria, yeast, and fungi.
Methylisothiazolinone’s used in the manufacture of water-based cosmetics and personal care products.
Methylisothiazolinone, better known by the acronym MIT, is used as a synthetic preservative in cosmetic products.
Methylisothiazolinone has been used as a substitute for parabens in so-called "paraben-free" products by a number of brands.


Methylisothiazolinone, or MIT as it is sometimes known, is a preservative used in cosmetics and beauty products.
Methylisothiazolinone is a powerful biocide, or “chemical substance capable of killing living organisms, usually in a selective way.
Biocides are a general term that includes antimicrobial, germicide, antibiotic, and antifungal.
Ultimately, Methylisothiazolinone is used to prevent a wide variety of bacteria and fungi from growing in cosmetics and beauty products, most often in shampoo.


Methylisothiazolinone is only approved for use in rinse-off formulas and at low concentrations.
Methylisothiazolinone is used to control slime-forming bacteria, fungi, and algae in pulp/paper mills, cooling water systems, oil field operations, industrial process waters, and air washer systems.
And Methylisothiazolinone is incorporated into adhesives, coatings, fuels, metal working fluids, resin emulsions, paints, and various other specialty industrial products as a preservative.


Methylisothiazolinone is also used to control the growth of mold, mildew, and sapstain on wood products.
Methylisothiazolinone is generally recommended for use only in rinse-off and leave-on cosmetic products (maximum concentration of 100 ppm) as preservative such as shampoo, conditioner, hair color, body wash, lotion, sunscreen, mascara, shaving cream, baby lotion, baby shampoo, hairspray, makeup remover, liquid soaps, and detergents.


Even though MIT doesn't have direct benefits for hair, it does have a number of benefits in a product formulation.
Methylisothiazolinoneprotects products at a very low-use level.
Methylisothiazolinone's also water soluble, making it very easy to mix in, It's also stable over a broad pH range, making it suitable for many types of formulas like shampoos and conditioners.
Methylisothiazolinone was initially used occupationally, in paints, adhesives/glues and cleaners etc, as a mixture with methylchloroisothiazolinone (MCI).


Since 2005, it has been widely used in cosmetics and household products, such as moist wipes, shampoos, cleaners and liquid laundry products.
Methylisothiazolinone is used as a biocide and preservative in cosmetics, paints, and glues.
Methylisothiazolinone is used as an antimicrobial in cosmetics, hygiene products, paints, emulsions, cutting oils, paper coatings, and water storage and cooling units.
Methylisothiazolinone is used as a biocide in textile production.


Methylisothiazolinone is used as a preservative in pesticide products.
Methylisothiazolinone is used as a biocide in pulp/paper mills, industrial process and cooling water systems, oil field operations, and air cleaner systems, and as a preservative in adhesives, coatings, fuels, metalworking fluids, resin emulsions, paints, and wood products.
Methylisothiazolinone is a biocide and is used to control microbial growth in water containing solutions.


Methylisothiazolinone is used for controlling microbial growth in water-containing solutions.
Methylisothiazolinone is typically used in a formulation with 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT), in a 3:1 mixture (CMIT:MIT) sold commercially.
In addition, Methylisothiazolinone serves as an antimicrobial agent in latex adhesives and in paper coatings that also contact food.
Methylisothiazolinone, along with other isothiazolinones, is a biocide widely used as a preservative in personal care products.


Methylisothiazolinone is also used in many industrial processes, such as paint and paper manufacturing, metalworking, mining, and sanitizing.
Methylisothiazolinone is a widely-used preservative.
Methylisothiazolinone is used preservative to keep home and personal care products in good condition: without them, they could be spoiled by bacteria, yeasts and moulds.


Methylisothiazolinone is a common preservative used in the personal care industry.
Methylisothiazolinone is also used, for example, in dishwashing liquids, liquid cleaning products, paint, glue, etc.
Methylisothiazolinone can be found in liquid construction products such as Ingredients will also be disclosed in such products.
Methylisothiazolinone functions as a biocide and preservative within the group of isothiazolinones and is widely used in cosmetics, shampoos, soaps and body care products, cooling fluids, etc.


Methylisothiazolinone is used as a preservative that’s generally recommended for use only in rinse-off products such as cleansers or shampoos.
Methylisothiazolinone (MIT) is a preservative that is found in a wide array of liquid cosmetics, personal care products and cleaning products on the market today.
Methylisothiazolinone's function is to inhibit the growth of bacteria.


Methylisothiazolinone is a preservative used in personal hygiene products (such as shampoos, lotions, emulsions, and sun screens), and in industrial cooling oils, cutting oils, and paper finishes. It is also commonly added to household cleaners as a substitute for formaldehyde.
Methylisothiazolinone is also used in air fresheners and may be a preservative component of a product.
Specifically, Methylisothiazolinone can be found in cleansers such as liquid dish soap, liquid laundry soap, all purpose spray cleaners and window cleaning solutions.


Methylisothiazolinone is a isothiazolinone based biocide and preservative used in personal care products.
Methylisothiazolinone is also used for controlling microbial growth in water-c ontaining solution.
Although Methylisothiazolinone may be used in cosmetics and personal care products alone, it is often used as a mixture with Methylchloroisothiazolinone [(MCI).


In cosmetics and personal care products historically, Methylisothiazolinone, or the mixture, Methylisothiazolinone and Methylchloroisothiazolinone, was used in various rinse-off and leave-on formulations including hair products, shampoos, skin care products, bath products, eye and facial makeup, wet wipes and suntan products.
Methylisothiazolinone is a widely used preservative and biocide.


Methylisothiazolinone hydrochloride is an isothiazolinone based biocide and preservative used in personal care products.
Methylisothiazolinone is also used for controlling microbial growth in water-containing solutions.
Methylisothiazolinone is used to studying the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites.


Methylisothiazolinone hydrochloride (Methylisothiazolinone hydrochloride) is a common preservative used in industrial products, owing to its strong biocide effect.
You’ll find Methylisothiazolinone and chemicals like it at low concentrations in “rinse-off” products like shampoos, conditioners, hair colors, body washes, laundry detergents, liquid hand soaps, bubble bath, hand dishwashing soaps, and shampoo/conditioner combinations.


Methylisothiazolinone is a preservative used in personal care products to stop fungus, bacteria and other microbes from growing in water solutions.
Methylisothiazolinone helps maintain product quality and performance over time.
Methylisothiazolinone is a biocide, a chemical substance that controls or kills microorganisms.


Methylisothiazolinone is often found in antibacterial and cleaning products and is used as a preservative.
Methylisothiazolinone is a synthetic ingredient that is commonly found in many household cleaners, including many so called "green cleaners" despite existing science that proves it causes harm to human health and aquatic life.
Methylisothiazolinone (MI or MIT) is part of a family of chemical preservatives which also includes benzisothiazolinone (BIT or BI), methylchloroisothiazolinone (MCI, CMI or CMIT), and octylisothiazolinone (OIT or OI).


Isothiazolinones are often used to extend a product’s shelf life and protect you against exposure to bacteria and fungi by inhibiting the growth of those organisms (collectively known as microbes or as we like to call them “bugs”).
Methylisothiazolinone was first registered in the U.S. in 1977 and initially used in paints, adhesives/glues and cleaners, especially in a mixture with methylchloroisothiazolinone.


Methylisothiazolinone is a preservative that can also be found in shampoos, skin care products and makeup.
Methylisothiazolinone helps maintain product quality and performance over time.
Methylisothiazolinone is used to extend a product’s shelf life and protect consumers against exposure to bacteria and mold by inhibiting the growth of those organisms.


Methylisothiazolinone is Preservative that’s generally recommended for use only in rinse-off products such as cleansers or shampoos.
Methylisothiazolinone or MIT is a preservative used in many consumer goods including cosmetic products, to preserve product quality and ensure consumer safety by preventing the growth of microbes.
Methylisothiazolinone is used to protect products from contamination by potentially pathogenic microbes (fungi and bacteria).


Since 2005, they have become widely used in cosmetics and household products.
Methylisothiazolinone is a widely-used preservative in many personal care products, specifically many hair care products.
Methylchloroisothiazolinone is a chemical used in skin care products, household cleaners, and industrial products as a preservative. It is usually mixed with methylisothiazolinone and the combination is sometimes called Kathon CG or Euxyl K 100.


-Methylisothiazolinone’s also used in industrial processes, including the manufacture of:
*paper coatings
*detergents
*paints
*glue
*cutting oils


-Hair Type Considerations:
Methylisothiazolinone can be used by all hair types.
Methylisothiazolinone is more important to be conscious of any allergies or skin you might have before using products containing the ingredient.



FUNCTIONS OF METHYLISOTHIAZOLINONE:
*Preservative:
Inhibits the development of micro-organisms in cosmetic products



WHAT PRODUCTS CAN CONTAIN METHYLISOTHIAZOLINONE?
*Household cleaning products
*Foundations/concealer
*Sunscreens, moisturizers, creams/lotions/gels
*Detergents/cleaners
*Bronzers/self-tanners
*Shampoo/conditioners
*Fabric softeners/ washing detergents
*Eye shadows, mascaras, makeup removes
*Bubble baths
*Polishes
*Soaps/hand washes/body washes
*Baby wet wipes



WHAT ARE SOME PRODUCTS THAT MAY CONTAIN METHYLISOTHIAZOLINONE?
*Body Washes/Hand Soaps/Moisturizers
*Cleaners
*Hair Products
• Hair Dyes
• Shampoos
• Conditioners
*Paint
*Pet Care
*Yard Care Products



BENEFITS OF METHYLISOTHIAZOLINONE FOR HAIR:
MIT does not have any benefits specifically for your hair.
Methylisothiazolinone won't make it shiny, more manageable, thicker, or stronger.
Methylisothiazolinone is strictly used in cosmetics as a preservative and bacteria-inhibitor, which is obviously an important thing we all want in a product we're keeping in a warm, damp place like the bathroom.



WHAT PRODUCTS IS METHYLISOTHIAZOLINONE IN?
Methylisothiazolinone is found in a multitude of products, including those claiming to be “natural”.
The list includes cleaning products, detergents, lotions, sunscreens, shampoos, conditioners, hair coloring, body washes, mascara, shaving cream, make-up remover, liquid soaps, and baby products including wipes, lotions and shampoos.



PREPARATION OF METHYLISOTHIAZOLINONE:
Methylisothiazolinone is prepared by cyclization of cis-N-methyl-3-thiocyanoacrylamide:
NCSCH = CHC(O)NHCH3⟶SCH = CHC(O)NCH3 + HCN



WHY IS METHYLISOTHIAZOLINONE USED IN COSMETICS AND PERSONAL CARE PRODUCTS?
Why is it used in cosmetics and personal care products?
Methylisothiazolinone and Methylchloroisothiazolinone (MCI) are preservatives.
Preservatives are natural or man-made ingredients designed to help ensure the safety and quality of products by protecting them against the growth of microorganisms during storage and, most importantly, during use by consumers.
Any product that contains water is particularly susceptible to being spoiled by microbial growth, causing problems such as discoloration, unpleasant odors or breakdown.
Under certain conditions, microorganisms can even grow to potentially harmful levels.
Preservatives are designed to help prevent these problems.



PHYSICAL and CHEMICAL PROPERTIES of METHYLISOTHIAZOLINONE:
Chemical formula: C4H5NOS
Molar mass: 115.1 g/mol
Appearance: white solid
Physical state Powder with lumps
Color: dark yellow
Odor: No data available
Melting point/freezing point:
Melting point/range: 46,7 - 48,3 °C
Initial boiling point and boiling range: > 130 °C at 16 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: 396 °C at 1.012 hPa
Decomposition temperature: No data available

pH: 2,58 at 50 g/l at 25 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: soluble
Partition coefficient: n-octanol/water:
log Pow: -0,34 at 30 °C
Bioaccumulation is not expected.
Vapor pressure: 0,0099 hPa at 20 °C
Density: 1,39 g/cm3 at 20 °C
Relative density: 1,39 at 20 °C
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none

Other safety information:
Surface tension: 68,8 mN/m at 1g/l at 19,5 °C
Dissociation constant: > 2,81 at 21 °C
Melting point: 254-256 °C(lit.)
Boiling point: bp0.03 93°
Density: 1.25 (14% aq.)
vapor pressure: storage temp.: 2-8°C
solubility: Chloroform, Ethyl Acetate
pka: -2.03±0.20(Predicted)
form: neat
color: Yellow
Water Solubility: 489g/L at 20℃



FIRST AID MEASURES of METHYLISOTHIAZOLINONE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of METHYLISOTHIAZOLINONE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up carefully.
Dispose of properly.



FIRE FIGHTING MEASURES of METHYLISOTHIAZOLINONE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of METHYLISOTHIAZOLINONE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Use tightly fitting safety goggles
*Body Protection:
Acid-resistant protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of METHYLISOTHIAZOLINONE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store under inert gas.



STABILITY and REACTIVITY of METHYLISOTHIAZOLINONE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available



SYNONYMS:
2-Methyl-1,2-thiazol-3(2H)-one
2-Methylisothiazol-3(2H)-one
2-Methyl-4-isothiazolin-3-one
2-METHYL-4-ISOTHIAZOLIN-3-ONE
2-METHYL-3(2H)-ISOTHIAZOLONE
2-Methylisothiazol-3(2H)-one
2-Methyl-4-isothiazolin-3-on
METHYLISOTHIAZOLONE
Casson preservatives
2-methyl-2H-isothiazol-3-one
2-METHYL-4-ISOTHIAZOLINE-3-ONE
2-Methyl-3-isothiazolone
2-Methyl-2H-isothiazole-3-one
2-Methyl-3-isothiazolone
2-Methyl-4-isothiazoline-3-ketone
2-Methyl-4-isothiazoline-3-one
N-Methylisothiazolin-3-one
2-Methyl-3(2H)-isothiazolone
2-Methyl-4-isothiazolin-3-one
2-Methyl-2H-isothiazol-3-one
2-Methyl-4-isothiazolin-3-one calcium chloride
3(2H)-Isothiazolone, 2-methyl-
2-Methyl-2,3-dihydroisothiazol-3-one
Neolone 950
2-Methylisothiazol-3(2H)-one
UN3261
Methylisothiazolinone
3(2H)-Isothiazolone, 2-methyl-
2-Methyl-2H-isothiazol-3-one
2-Methyl-4-isothiazolin-3-one
2-Methyl-3(2H)-isothiazolone
MI
MIT
2-Methyl-4-isothiazoline-3-one
Neolone 950 preservative
OriStar MIT
Microcare MT

METHYLISOTHIAZOLINONE (MI)
Methylisothiazolinone (MI), is a powerful synthetic biocide and preservative within the group of isothiazolinones.
Methylisothiazolinone (MI) is used to control slime-forming bacteria, fungi, and algae in pulp/paper mills, cooling water systems, oil field operations, industrial process waters, and air washer systems.
And Methylisothiazolinone (MI) is incorporated into adhesives, coatings, fuels, metal working fluids, resin emulsions, paints, and various other specialty industrial products as a preservative.

CAS: 2682-20-4
MF: C4H5NOS
MW: 115.15
EINECS: 220-239-6

Synonyms
1-(4-CHLOROPHENYL)-3-(3,4-DICHLOROPHENYL)UREA;2-METHYL-4-ISOTHIAZOLIN-3-ONE;2-METHYL-4-ISOTHIAZOLINE-3-ONE;2-METHYL-3(2H)-ISOTHIAZOLONE;N-METHYL-3-OXODIHYDRO ISOTHIAZOLE;2-methyl-3(2h)-isothiazolon;Isothiazolone,2-methyl-;Methylisothiazolinone;2682-20-4;2-Methyl-4-isothiazolin-3-one;Methylisothiazolinone;2-Methyl-3(2H)-isothiazolone;2-methylisothiazol-3(2h)-one;2-Methyl-4-isothiazoline-3-one;3(2H)-Isothiazolone, 2-methyl-;N-Methyl-3-oxodihydroisothiazole;N-METHYL-3-OXODIHYDRO ISOTHIAZOLE;2-methyl-3-isothiazolone;2-METHYL-2H-ISOTHIAZOL-3-ONE;MIT;2-methyl-1,2-thiazol-3(2H)-one;229D0E1QFA;DTXSID2034259;CHEBI:53620;2682-20-4 (free base);MFCD01742315;Neolone;Caswell No. 572A;Microcare MT;Kordek MLX;EINECS 220-239-6;MIT (biocide);Acticide M 10;Acticide M 20bv;Bestcide 600;Kordek 50;Kordek 50C;2-methyl-1,2-thiazol-3-one;Kordek 573F;Kathon CG 243;n-methylisothiazolin-3-one;UNII-229D0E1QFA
;Neolone 950; 2-Methyl-4-isothiazolin-3-one; 2-Methylisothiazol-3-one;HSDB 8200;MIT 950;MT 10;2-Methyl-4-isothiazoline-3-ketone;KB 838;2-Methyl-4-isothiazolin-3-one (MI);2-methyl-4-isothiazolinone;SCHEMBL17863;SCHEMBL113898;Methylisothiazolinone free base;CHEMBL1620780;DTXCID0014259;METHYLISOTHIAZOLINONE [II];METHYLISOTHIAZOLINONE [MI];2-Methyl-4-isothiazolin-3-one 100 microg/mL in Acetonitrile;2-Methyl-3(2H)-isothiazolone #;METHYLISOTHIAZOLINONE [VANDF];Tox21_303814;BBL104136;METHYLISOTHIAZOLINONE [MART.];STL557951;AKOS007930246;AM84857;CS-W011236;HY-W010520;2-Methyl-4-isothiazolin-3-one, 95%;NCGC00357093-01;CAS-2682-20-4;2-methyl-2,3-dihydro-1,2-thiazol-3-one;DB-005250;NS00003875;F21330;EN300-1708622;Q423870;2-Methyl-4-isothiazolin-3-one, analytical standard

Methylisothiazolinone (MI) is also used to control the growth of mold, mildew, and sapstain on wood products.
Methylisothiazolinone (MI) is generally recommended for use only in rinse-off and leave-on cosmetic products (maximum concentration of 100 ppm) as preservative such as shampoo, conditioner, hair color, body wash, lotion, sunscreen, mascara, shaving cream, baby lotion, baby shampoo, hairspray, makeup remover, liquid soaps, and detergents.
Nevertheless, methylisothiazolinone is allergenic.
Methylisothiazolinone (MI) is reported that methylisothiazolinone in rinse-off products causes allergic contact dermatitis.
Methylisothiazolinone (MI) is an isothiazolinone-derived biocide used for controlling microbial growth in industrial and household products, often in a mixture with 5-chloro-2-methyl-3-isothiazolone (MCI).
Methylisothiazolinone (MI) is active against Gram-positive and Gram-negative bacteria, fungi, and yeast with MIC values of 0.0045, 0.0015, >0.01, and 0.0065% (w/w) for S. aureus, P. aeruginosa, A. niger, and C. albicans, respectively, when used alone.

MIC values are 7 to 200-fold lower when Methylisothiazolinone (MI) is used in combination with MCI.
Methylisothiazolinone (MI) decreases neurite outgrowth of rat cortical neurons when used at concentrations of 0.1-3 μM and inhibits Src family kinases in cell-free assays.
Methylisothiazolinone (MI), alone and as a mixture with MCI, can elicit contact sensitization.
Methylisothiazolinone (MI) is a 1,2-thazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom.
Methylisothiazolinone (MI) is a powerful biocide and preservative and is the minor active ingredient in the commercial product Kathon(TM).
Methylisothiazolinone (MI) has a role as an antifouling biocide, an antimicrobial agent and an antifungal agent.
Methylisothiazolinone (MI), MIT, or MI, is the organic compound with the formula S(CH)2C(O)NCH3.

Methylisothiazolinone (MI) is a white solid.
Isothiazolinones, a class of heterocycles, are used as biocides in numerous personal care products and other industrial applications.
Methylisothiazolinone (MI) and related compounds have attracted much attention for their allergenic properties, e.g. contact dermatitis.
Methylisothiazolinone (MI) and Methylchloroisothiazolinone (CMIT) may be hard to pronounce, but they can be even harder on the body.
These common preservatives are found in many liquid personal care products, and have been linked to lung toxicity, allergic reactions, and possible neurotoxicity.

Methylisothiazolinone (MI) is a synthetic preservative that is commonly used in personal care products and cosmetics due to its ability to inhibit bacterial and fungal growth.
Methylisothiazolinone (MI) extends the shelf life of products and is specifically beneficial for water-based cosmetics.
However, Methylisothiazolinone (MI) comes at a cost - Methylisothiazolinone has garnered attention for potential skin sensitization issues, leading to regulatory scrutiny and label warnings.
In high concentrations, Methylisothiazolinone (MI) can cause skin burns and severe allergies.
Therefore, a lot of personal care brands are opting for alternatives such as Phenoxyethanol in leave-on products.
Other names of Methylisothiazolinone (MI) include Neolone 950 preservative, 2-methyl-4-isothiazoline-3-one, MI, Microcare MT, and OriStar MIT.

Methylisothiazolinone (MI) is a liquid biocide with outstanding advantages such as rapid inhabitation of growth and macromolecule synthesis, broad spectrum activity, effective at low concentration and against biofilm as well as a wide pH range, biodegradable non-persistent in the environment, non-surface activity, infrequent dosing, easily deactivated, compatibility, low toxicity, water soluble, non-foaming, cost effectiveness etc.
The active ingredient is a mixture of two isothiazolines.
Methylisothiazolinone (MI) is ideally suited to meet the requirement of an industrial water treatment biocide for bacteria, fungi and algae paper mill slimicide.

Methylisothiazolinone (MI) Chemical Properties
Melting point: 254-256 °C(lit.)
Boiling point: bp0.03 93°
Density: 1.25 (14% aq.)
Vapor pressure: <0.1 mm Hg ( 25 °C)
Storage temp.: 2-8°C
Solubility: Chloroform, Ethyl Acetate
pka: -2.03±0.20(Predicted)
Form: Solid
Color: Yellow
Water Solubility: 489g/L at 20℃
BRN: 606203
InChIKey: BEGLCMHJXHIJLR-UHFFFAOYSA-N
LogP: -0.486 at 20℃
CAS DataBase Reference: 2682-20-4(CAS DataBase Reference)
NIST Chemistry Reference: Methylisothiazolinone (MI) (2682-20-4)
EPA Substance Registry System: Methylisothiazolinone (MI) (2682-20-4)

Methylisothiazolinone (MI) is a colorless,clear liquid with amild odor that is completely soluble in water; mostly soluble in acetonitrile, methanol, and hexane; and slightly soluble in xylene.
Methylisothiazolinone (MI) is a heterocyclic organic compound used as a preservative in cosmetics and personal care products in concentrations up to 0.01%.

Uses
Methylisothiazolinone (MI), or MIT as it is sometimes known, is a preservative used in cosmetics and beauty products.
Methylisothiazolinone (MI) is a powerful biocide, or “chemical substance capable of killing living organisms, usually in a selective way.”Biocides are a general term that includes antimicrobial, germicide, antibiotic, and antifungal.
Ultimately, Methylisothiazolinone (MI) is used to prevent a wide variety of bacteria and fungi from growing in cosmetics and beauty products, most often in shampoo.
Methylisothiazolinone (MI) is only approved for use in rinse-off formulas and at low concentrations.
Methylisothiazolinone (MI) is a isothiazolinone based biocide and preservative used in personal care products.

Methylisothiazolinone (MI) is also used for controlling microbial growth in water-c ontaining solution.
Methylisothiazolinone (MI) is a preservative compound widely used in cosmetics.
Methylisothiazolinone (MI) is a contact allergen and sensitiser.
Methylisothiazolinone (MI) has recently been identified as a neurotoxin that can damage nerve endings with repeated exposure.
Methylisothiazolinone (MI) or MIT is a powerful antimicrobial and antifungal agent which is widely used in personal care products.
Methylisothiazolinone (MI) is also used in industrial applications as a preservative and antifouling agent.

Preparation
Methylisothiazolinone (MI) is prepared by cyclization of
cis-N-methyl-3-thiocyanoacrylamide: NCSCH=CHC(O)NHCH3?SCH=CHC(O)NCH3+HCN

Preparation
Methylisothiazolinone (MI) is prepared by cyclization of cis-N-methyl-3-thiocyanoacrylamide:

Hazard
Methylisothiazolinone (MI) is allergenic and cytotoxic, and this has led to some concern over its use.
A report released by the European Scientific Committee on Cosmetic Products and Non-food Products Intended for Consumers (SCCNFP) in 2003 also concluded that insufficient information was available to allow for an adequate risk assessment analysis of Methylisothiazolinone (MI).

Side effects
Early on, dermatitis may occur only on part of the exposed skin.
Common patterns include: hand dermatitis,perianal dermatitis, perivulval dermatitis, napkin dermatitis, facial dermatitis, eyelid swelling, and scalp dermatitis.
Later, more extensive and severe whole-body contact dermatitis may occur in very sensitive people.
METHYLPARABEN
Methylparaben is a pheromone in wolves produced during estrus associated with the behavior of alpha male wolves preventing other males from mounting females in heat.
Methylparaben resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol.
Methylparaben is the most frequently used antimicrobial preservative in cosmetics.

CAS Number: 99-76-3
Molecular Formula: C8H8O3
Molecular Weight: 152.15
EINECS Number: 202-785-7

Synonyms: Methylparaben, METHYLPARABEN1, 99-76-3, Methyl paraben, Methyl p-hydroxybenzoate, Nipagin, Methyl parahydroxybenzoate, Tegosept M, Moldex, Maseptol, Preserval M, Methaben, Metoxyde, Preserval, Metaben, Paridol, Septos, Solbrol, Methyl butex, p-Hydroxybenzoic acid methyl ester, p-Methoxycarbonylphenol, Benzoic acid, 4-hydroxy-, methyl ester, Methyl chemosept, p-Carbomethoxyphenol, 4-Hydroxybenzoic acid methyl ester, Methyl parasept, Nipagin M, Aseptoform, Methylben, Abiol, Methyl-p-hydroxybenzoate, Methyl p-oxybenzoate, Solbrol M, 4-(Methoxycarbonyl)phenol, 4-Hydroxybenzoic acid, methyl ester, FEMA No. 2710, Killitol, p-Hydroxybenzoic methyl ester, FEMA Number 2710, Methyl ester of p-hydroxybenzoic acid, p-Oxybenzoesauremethylester, Methylparaben e218, NSC 3827, MFCD00002352, CCRIS 3946, Benzoic acid, p-hydroxy-, methyl ester, HSDB 1184, Methyl paraben (e218), methyl 4- hydroxybenzoate, Methyl-d3Paraben, UNII-A2I8C7HI9T, NSC-3827, p-Hydroxybenzoic acid, methyl ester, EINECS 202-785-7, A2I8C7HI9T, EPA Pesticide Chemical Code 061201, NSC-406127, BRN 0509801, methyl hydroxybenzoate, DTXSID4022529, INS number 218, CHEBI:31835, Methylis hydroxybenzoas, AI3-01336, INS-218, 4-HYDROXY-BENZOIC ACID METHYL ESTER, Methylester kyseliny p-hydroxybenzoove, E218, CHEMBL325372, DTXCID402529, INS NO.218, E-218, NSC3827, EC 202-785-7, 4-Hydroxybenzoic acid-methyl ester, NCGC00159376-02, NCGC00159376-04, E 218, METHYLPARABEN (II), METHYLPARABEN [II], WLN: QR DVO1, METHYLPARABEN (USP-RS), METHYLPARABEN [USP-RS], Methylparaben [USAN], Caswell No. 573PP, 4-Hydroxybenzoic acid-methyl ester 1000 microg/mL in Acetonitrile, METHYL HYDROXYBENZOATE (MART.), METHYL HYDROXYBENZOATE [MART.], CAS-99-76-3, SMR000036660, METHYL PARAHYDROXYBENZOATE (EP MONOGRAPH), METHYL PARAHYDROXYBENZOATE [EP MONOGRAPH], METHYL SALICYLATE IMPURITY C (EP IMPURITY), METHYL SALICYLATE IMPURITY C [EP IMPURITY], p-Oxybenzoesauremethylester [German], Methylparaben [USAN:NF], PROPYL HYDROXYBENZOATE IMPURITY B (EP IMPURITY), PROPYL HYDROXYBENZOATE IMPURITY B [EP IMPURITY], Metagin, METHYL4-HYDROXYBENZOATE, Lexgard M, Paraben M, Methylester kyseliny p-hydroxybenzoove [Czech], (Methyl Paraben), Methylparaben, NF, Methylparaben, FCC, 4-carbomethoxyphenol, Methylparaben (NF), Methylparaben (TN), Solparol (Salt/Mix), methyl 4-hydoxybenzoate, methyl 4 hydroxybenzoate, methyl 4-hydroxylbenzoate, methyl 4-hydroxy-benzoate, methyl-4-hydroxy-benzoate, Methyl 4-?Hydroxybenzoate, METHYLPARABEN [MI], Preserval MS (Salt/Mix), bmse010009, methyl (4-hydroxy)benzoate, METHYLPARABEN [FCC], cid_7456, SCHEMBL4440, isLeaf Tattoo Eyebrow Brown, METHYLIS HYDROXYBENZOAS [WHO-IP LATIN], D01400, Methylparaben, USP, 98.0-102.0%, A846079, Q229987, Q-200479, Methylparaben, SAJ first grade, >=98.0%, Methylparaben, tested according to Ph.Eur., Z19674820, F1908-0119, Methylparaben, BioXtra, >=99.0% (titration), Methylparaben, certified reference material, TraceCERT(R), Methylparaben, ReagentPlus(R), >=99.0%, crystalline, Methylparaben, United States Pharmacopeia (USP) Reference Standard, InChI=1/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H, Methylparaben, BioReagent, suitable for insect cell culture, Methyl parahydroxybenzoate, European Pharmacopoeia (EP) Reference Standard, Methylparaben, Pharmaceutical Secondary Standard; Certified Reference Material

Methylparaben is a pheromone in wolves produced during estrus associated with the behavior of alpha male wolves preventing other males from mounting females in heat.
Methylparaben is an anti-fungal agent often used in a variety of cosmetics, personal-care products and food preservatives.
Methylparaben is used as an anti-fungal agent.

Methylparaben is also used as a preservative in foods, beverages and cosmetics.
Methylparaben acts as an inhibitor of growth of molds and to lesser extent bacteria and as a vehicle for ophthalmic solution.
Methylparaben is a standardized methyl paraben allergen isolated from Yunnan hemlock (Tsuga dumosa).

Methylparaben is commonly used as a stable, non-volatile preservative.
Methylparaben increases histamine release and cellular regulation of immunity, blocks sodium channels, and prevents ischemia-reperfusion injury.
Methylparaben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen.

Methylparaben is a stable, non-volatile compound used as an antimicrobial preservative in foods, drugs and cosmetics.
The physiologic effect of Methylparaben is by means of increased histamine release, and cell-mediated immunity.
Methylparaben is widely used as a preservative in the cosmetic, pharmaceutical, and food industries.

Methylparaben helps prevent the growth of bacteria, mold, and yeast in various products, extending their shelf life.
Methylparaben is often used alongside other parabens for enhanced preservative efficacy.
Methylparaben is listed on ingredient labels under various names, including Methylparaben, METHYLPARABEN, and E218.

While it has been widely used, there has been some debate and research regarding the safety of parabens in cosmetic and personal care products, leading to the development of alternative preservatives in some formulations.
Methylparaben, also called methyl paraben or nipagin, comprises the ester of p-hydroxybenzoic acid.
Methylparaben is present naturally in cloudberry, white wine and bourbon vanilla.

Methylparaben has antimicrobial and antifungal functionality and is commercially used as a preservative in the food, cosmetic and pharmaceutical industry.
Methylparaben has cytotoxic effects on keratinocytes in the presence of sunlight.
Methylparaben upon solar irradiation mediates DNA damage and modulates esterase metabolism resulting in skin damage and favors cancer progression.

Methylparaben has estrogenic functionality and upregulates estrogen-related genes
Methylparaben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen.
Methylparaben sulfate belongs to the class of organic compounds known as phenylsulfates.

Phenylsulfates are compounds containing a sulfuric acid group conjugated to a phenyl group.
Based on a literature review very few articles have been published on Methyl-4-hydroxybenzoate sulfate.
The chemical structure of Methylparaben consists of a benzene ring with a hydroxyl group (-OH) and a methyl ester group (-COOCH3) attached to the para position of the ring.

Methylparaben is known by various common names, including Methylparaben, Methaben, Nipagin M, and Methyl p-hydroxybenzoate.
Methylparaben is widely used as a preservative in cosmetics, skincare products, personal care products, and pharmaceuticals to prevent the growth of microorganisms and increase product shelf life.
Methylparaben is also utilized as a preservative in certain food products.

In pharmaceutical formulations, Methylparaben can be used to preserve the stability of drugs.
Methylparaben, along with other parabens, has been the subject of some research and discussion regarding its safety.
Some studies have suggested potential concerns about parabens being endocrine disruptors, but regulatory bodies have generally deemed them safe for use within established limits.

Regulatory agencies such as the FDA, EFSA, and Cosmetic Ingredient Review (CIR) have reviewed the safety of parabens and set concentration limits for their use in various products.
Due to consumer preferences and evolving regulations, there has been an increased interest in the development and use of alternative preservatives, such as natural or nature-derived preservatives, in some cosmetic and personal care products.

Methylparaben exhibits antimicrobial properties, which is the primary reason for its use as a preservative.
Methylparaben helps prevent the growth of bacteria, yeast, and mold in various products.
Methylparaben is part of a family of parabens, which includes ethylparaben, propylparaben, and butylparaben.

Methylparabens share a similar structure and are used for similar preservative purposes.
Methylparaben is compatible with a wide range of formulations, including creams, lotions, shampoos, and other personal care and cosmetic products.
In the pharmaceutical industry, Methylparaben is sometimes used to preserve the stability of certain medications and prevent microbial contamination.

Regulatory agencies, such as the FDA and the European Commission, have established concentration limits for parabens in cosmetic and personal care products to ensure their safe use.
Methylparaben is also approved for use as a food additive, where it functions as a preservative to extend the shelf life of certain food products.
The safety of Methylparaben has been assessed through various scientific studies, and it has undergone reviews by regulatory bodies to determine its safety for use in cosmetics and other consumer products.

Increased consumer awareness about cosmetic ingredients has led to a demand for transparency in labeling.
Some consumers actively seek products labeled as "paraben-free" due to personal preferences or concerns.
In response to consumer demand, some cosmetic and personal care brands are exploring and using natural or nature-derived preservatives as alternatives to synthetic ones like parabens.

Methylparaben is widely accepted as a preservative in cosmetic and personal care formulations globally.
Methylparaben is use is regulated by various authorities to ensure consumer safety.
Methylparaben is the methyl ester of p-hydroxybenzoic acid.

Methylparaben, commonly known as Methylparaben, is a chemical compound with the molecular formula C8H8O3.
Methylparaben, 99% - one of the parabens, is a preservative with the chemical formula CH3(C6H4(OH)COO).
Methylparaben is also called methylparaben.

This paraben is a white crystalline powder or colorless crystals.
Methylparaben is freely soluble in alcohol, ether, and acetone and very slightly soluble in water.
Methylparaben boiling point is 270~280℃.

Methylparaben by Zhejiang Shengxiao Chemicals is a preservative.
Methylparaben is suitable for cosmetics.
Methylparaben occurs naturally in several fruits, particularly in blueberries.

Methylparaben has a role as a plant metabolite, an antimicrobial food preservative, a neuroprotective agent and an antifungal agent.
Methylparaben is produced through the methanol esterification of p-hydroxybenzoic acid in the presence of sulfuric acid.
Methylparaben is slightly soluble in water but easily dissolves in ethanol, ether, acetone, and other organic solvents.

Methylparaben one of the parabens, is a preservative with the chemical formula CH3(C6H4(OH)COO).
Methylparaben is a colorless crystalline powder with a faint characteristic odor and a slight burning taste.
One gram can dissolve in 2.5 ml of ethanol, approximately 4 ml of propylene glycol, or 400 ml of water at 25°C or about 50 ml of water at 80°C.

Methylparaben is commonly used as a fungistat in soft drinks, non-leavened bakery products, and other products, with a permissible level of up to 0.1%.
To inhibit Gram-positive bacteria, 1000 to 4000 ppm are required, and its effectiveness increases with decreasing pH, similar to benzoates.
Methylparaben is the methyl ester of 4-hydroxybenzoic acid.

Methylparaben is a white, crystalline powder that is soluble in alcohol and slightly soluble in water.
Methylparaben is a type of paraben.
Methylparabens are chemicals that are often used as preservatives to give products a longer shelf life.

Methylparaben one of the parabens, is a preservative with the chemical formula CH3(C6H4(OH)COO).
Methylparaben is the methyl ester of p-hydroxybenzoic acid.
Methylparaben serves as a pheromone for a variety of insects and is a component of queen mandibular pheromone.

The materials are heated in a glass-lined reactor and distilled under reflux.
The resulting acid is neutralized with caustic soda, then crystallized through cooling.
The crystallized product is centrifuged, washed, dried under vacuum, milled and blended, all in corrosion-resistant equipment to avoid metallic contamination.

Methylparaben is basically a methyl ester of p-hydroxybenzoic acid.
Methylparaben is non-toxic, and non-carcinogenic in nature.
Methylparaben is a stable, non-volatile compound and finds application as an anti-microbial preservative in foods, drugs and cosmetics.

Methylparaben is readily absorbed through the skin and gastrointestinal tract.
Upon hydrolyzation, it is hydrolyzed to p-hydroxybenzoic acid, and the conjugates formed get rapidly excreted in the urine.
Methylparaben serves as a pheromone for a variety of insects and is a component of queen mandibular pheromone.

Melting point: 125-128 °C (lit.)
Boiling point: 298.6 °C
Density: 1,46g/cm
vapor pressure: 0.000005 hPa (20 °C)
refractive index: 1.4447 (estimate)
FEMA: 2710 | METHYL P-HYDROXYBENZOATE
Flash point: 280°C
storage temp.: room temp
solubility: ethanol: soluble0.1M, clear, colorless
pka: pKa 8.15(H2O,t =20.0) (Uncertain)
form: Crystalline Powder
color: White to almost white
PH: 5.8 (H2O, 20°C) (saturated solution)
Odor: odorless or faint char. odor, sl. burning taste
Water Solubility: Slightly soluble in water.
FreezingPoint: 131℃
Merck: 14,6107
BRN: 509801
Stability: Stable. Incompatible with strong oxidizing agents, strong bases.
InChIKey: LXCFILQKKLGQFO-UHFFFAOYSA-N
LogP: 1.98 at 20℃

Methylparaben is generally considered to be biodegradable, but its presence in the environment has led to discussions about its potential accumulation and environmental impact.
Formulators often use a combination of preservatives to achieve a broad-spectrum antimicrobial effect while minimizing the concentration of each individual preservative.
The packaging of products containing Methylparaben should be carefully chosen to prevent contamination, as preservatives play a crucial role in maintaining the integrity of the product during its shelf life.

Increased consumer awareness about cosmetic ingredients has led to greater scrutiny of preservatives like Methylparaben.
Some consumers actively seek products labeled as "paraben-free" or opt for alternatives perceived as more natural.
The safety and use of Methylparaben are subject to ongoing evaluation by regulatory bodies, and any new scientific findings may influence regulations and industry practices.

Parabens are esters formed by p-hydroxybenzoic acid and an alcohol.
They are largely used as biocides in cosmetics and toiletries, medicaments, or food.
They have synergistic power with other biocides.

Parabens can induce allergic contact dermatitis, mainly in chronic dermatitis and wounded skin.
Methylparaben is soluble in alcohol and acetone but only slightly soluble in water.
Methylparaben demonstrates good stability under normal storage conditions, which contributes to its effectiveness as a preservative.

Methylparaben is often used in combination with other parabens, such as ethylparaben, propylparaben, and butylparaben, to create a broader spectrum of antimicrobial activity.
Methylparaben has been approved for use as a food additive and preservative by regulatory agencies, including the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA).

Methylparaben should be stored in a well-closed container in a cool, dry place.
Methylparaben is widely accepted in many countries for use in a variety of products, including skincare, haircare, and pharmaceuticals.

Methylparaben is one of the parabens family.
Methylparaben is also listed in the United States Pharmacopeia (USP) and other pharmacopeias as a standard for pharmaceutical formulations.
On ingredient labels, Methylparaben may be listed under its chemical name "Methylparaben," as "METHYLPARABEN," or by its E number "E218."

Methylparaben is widely used globally, and its acceptance as a preservative in various products has led to its inclusion in a wide range of consumer goods.
Ongoing research continues to explore the safety and potential alternatives to parabens in cosmetic and personal care products.
Some companies have opted to formulate products without parabens in response to consumer preferences for "paraben-free" options.

Parabens, including Methylparaben, have been detected in the environment, including in water systems.
Research is ongoing to understand the potential environmental impact of these compounds.
Methylparaben has been in use since the early 20th century and gained popularity for its effectiveness as a preservative in cosmetics and personal care products.

Methylparaben is effective over a wide pH range, making it versatile for use in formulations with varying acidity or alkalinity.
In addition to its antibacterial properties, Methylparaben also exhibits antifungal activity, helping to prevent the growth of mold and yeast in formulations.
Regulatory agencies, such as the Cosmetic Ingredient Review (CIR), have established maximum concentrations for the use of Methylparaben in cosmetic and personal care products to ensure safety.

Storage:
Aqueous solutions of Methylparaben at pH 3–6 may be sterilized by autoclaving at 120°C for 20 minutes, without decomposition.
Aqueous solutions at pH 3–6 are stable (less than 10% decomposition) for up to about 4 years at room temperature, while aqueous solutions at pH 8 or above are subject to rapid hydrolysis (10% or more after about 60 days storage at room temperature);

Uses:
Methylparaben is widely used as a preservative in cosmetics and personal care products, including creams, lotions, shampoos, conditioners, deodorants, and makeup.
Methylparaben helps prevent the growth of bacteria, yeast, and mold, extending the shelf life of these products.
In the pharmaceutical industry, Methylparaben is utilized to preserve the stability of certain medications and prevent microbial contamination.

Methylparaben is commonly found in topical formulations, oral medications, and injectables.
Methylparaben is approved as a food additive, where it functions as a preservative to extend the shelf life of certain food products.
Methylparaben is used in some food items, such as baked goods, beverages, and sauces.

Methylparaben may be used in industrial settings where a preservative is needed to prevent microbial growth in products such as adhesives, lubricants, and cutting fluids.
Some medical and healthcare products, such as ointments, creams, and topical solutions, may contain Methylparaben as a preservative to maintain product integrity.
Methylparaben may be used in laboratories and research settings as a preservative for certain solutions and reagents to prevent contamination.

Methylparaben is often used in combination with other parabens (such as ethylparaben, propylparaben, and butylparaben) to create a synergistic preservative effect, providing a broader spectrum of antimicrobial activity.
This combination enhances the overall efficacy of the preservative system.
In addition to its preservative role, Methylparaben may contribute to the stabilization of formulations.

Methylparaben helps maintain the chemical and physical stability of products over time.
Methylparaben is effective over a range of pH levels, making it versatile for use in various formulations that may have acidic, neutral, or slightly alkaline conditions.
Methylparaben helps prevent the spoilage of cosmetic and personal care products by inhibiting the growth of microorganisms that can lead to changes in color, odor, and
texture.

Methylparaben has received regulatory approval from authorities such as the U.S. Food and Drug Administration (FDA), the European Commission, and other regulatory bodies worldwide for its use as a preservative in cosmetics, pharmaceuticals, and food products.
Due to its solubility in water, Methylparaben is commonly used in water-based formulations, including aqueous solutions, creams, and lotions.
Beyond cosmetics and personal care items, Methylparaben may be present in various consumer goods, including household products, to prevent microbial growth and ensure product longevity.

Methylparaben is compatible with a wide range of ingredients commonly found in cosmetic and personal care formulations, making it a versatile choice for product preservation.
Methylparaben is the ester of methyl alcohol and p-hydroxybenzoic acid, It is a bacteriostatic agent and preservative that was added to local anesthetic agents without vasoconstrictors before 1984 to prevent bacterial growth.

Allergic reactions developed from repeated exposures to parabens led to the removal of this agent from dental anesthetic solutions.
Similar products produced by similar production methods, like ethyl p-hydroxybenzoate (paraben B) and propyl p-hydroxybenzoate (Nepalese c), are also disinfectant preservatives.
Methylparabens are irritating to the skin.

Methylparaben is used as an anti-fungal agent.
Methylparaben is also used as a preservative in foods, beverages and cosmetics.
Methylparaben acts as an inhibitor of growth of molds and to lesser extent bacteria and as a vehicle for ophthalmic solution.

Methylparaben is often used in combination with other parabens, such as ethylparaben, propylparaben, and butylparaben, to create a synergistic preservative effect.
This combination broadens the spectrum of antimicrobial activity.
Methylparaben is effective in preserving aqueous (water-based) solutions, making it suitable for a wide range of formulations where water is a significant component.

Methylparaben exhibits stability over a range of pH levels, making it suitable for use in formulations with varying acidity or alkalinity.
Methylparaben has received regulatory approval for use in cosmetics, personal care products, pharmaceuticals, and food items by various regulatory agencies, including the U.S. FDA, European Commission, and other global authorities.

The primary function of Methylparaben is to prevent microbial spoilage by inhibiting the growth of bacteria, yeast, and mold. This property is crucial for maintaining the safety and quality of various consumer products.
Its solubility in water makes Methylparaben suitable for use in water-based formulations, contributing to its versatility in different types of cosmetic and personal care products.
Methylparaben undergoes stability testing to ensure its effectiveness over the intended shelf life of products.

This is particularly important in formulations where extended stability is required.
Cosmetic and personal care formulators conduct compatibility testing to ensure that Methylparaben does not interfere with the stability or performance of other ingredients in a formulation.
Methylparaben has been in use as a preservative for several decades, and its acceptance in various industries reflects its historical effectiveness and reliability.

Methylparaben and propylparaben are the most common of these. parabens is one of the most commonly used group of preservatives in the cosmetic, pharmaceutical, and food industries.
Parabens provide bacteriostatic and fungistatic activity against a diverse number of organisms, and are considered safe for use in cosmetics, particularly in light of their low sensitizing potential.
An evaluation of preservatives for use in leave-on cosmetic preparations lists parabens among the least sensitizing.

The range of concentrations used in cosmetics varies between 0.03 and 0.30 percent, depending on the conditions for use and the product to which the paraben is added.
Methylparaben is one of the most popular preservatives in beauty products and food items.
According to the National Library of Medicine, the ingredient occurs naturally in a handful of fruits—like blueberries—though it can also be created synthetically.

Methylparaben's found in everything from cream cleansers and moisturizers to primers and foundations and helps these products maintain their effectiveness.
Rabach says that it's chock-full of anti-fungal and antibacterial properties, which work wonders to extend the shelf life of skincare, haircare, and cosmetic products.
Methylparaben is widely used as an antimicrobial preservative in cosmetics, food products, and pharmaceutical formulations; see Table I.

Methylparaben may be used either alone or in combination with other methylparaben is the most frequently used antimicrobial preservative.
The parabens are effective over a wide pH range and have a broad spectrum of antimicrobial activity, although they are most effective against yeasts and molds.
Antimicrobial activity increases as the chain length of the alkyl moiety is increased, but aqueous solubility decreases; therefore a mixture of parabens is frequently used to provide effective preservation.

Preservative efficacy is also improved by the addition of propylene glycol (2–5%), or by using parabens in combination with other antimicrobial agents such as imidurea.
Owing to the poor solubility of the parabens, paraben salts (particularly the sodium salt) are more frequently used in formulations. However, this raises the pH of poorly buffered formulations.
Methylparaben together with propylparaben (0.02%) has been used for the preservation of various parenteral pharmaceutical formulations;

Methylparaben is an anti-fungal agent often used in a variety of cosmetics and personal-care products.
Methylparaben is also used as a food preservative and has the E number E218.

Methylparaben is commonly used as a fungicide in Drosophila food media at 0.1%.
To Drosophila, Methylparaben is toxic at higher concentrations, has an estrogenic effect (mimicking estrogen in rats and having anti-androgenic activity), and slows the growth rate in the larval and pupal stages at 0.2%.

Safety Profile:
Methylparaben and other parabens are widely used as antimicrobial preservatives in cosmetics and oral and topical pharmaceutical formulations.
Although parabens have also been used as preservatives in injections and ophthalmic preparations, they are now generally regarded as being unsuitable for these types of formulations owing to the irritant potential of the parabens.

These experiences may depend on immune responses to enzymatically formed metabolites of the parabens in the skin.
Unexpectedly, preparations containing parabens may be used by patients who have reacted previously with contact dermatitis provided they are applied to another, unaffected, site.
This has been termed the paraben paradox.

Concern has been expressed over the use of methylparaben in infant parenteral products because bilirubin binding may be affected, which is potentially hazardous in hyperbilirubinemic neonates.
There is controversy about whether methylparaben or propylparabens are harmful at concentrations typically used in body care or cosmetics.
Methylparaben and propylparaben are considered generally recognized as safe (GRAS) by the USFDA for food and cosmetic antibacterial preservation.

Methylparabenis readily metabolized by common soil bacteria, making it completely biodegradable.
Methylparaben is readily absorbed from the gastrointestinal tract or through the skin.
Methylparaben is hydrolyzed to p-hydroxybenzoic acid and rapidly excreted in urine without accumulating in the body.

Acute toxicity studies have shown that Methylparaben is practically non-toxic by both oral and parenteral administration in animals.
In a population with normal skin, Methylparaben is practically non-irritating and non-sensitizing; however, allergic reactions to ingested parabens have been reported.
A 2008 study found no competitive binding for human estrogen and androgen receptors for Methylparaben, but varying levels of competitive binding were seen with butyl- and isobutyl-paraben.


METHYLPARABEN ( Hydroxybenzoate de méthyle)
METHYLPROPANEDIOL, N° CAS : 2163-42-0, Nom INCI : METHYLPROPANEDIOL. Nom chimique : 2-Methyl-1,3-propanediol. N° EINECS/ELINCS : 412-350-5. Ses fonctions (INCI), Solvant : Dissout d'autres substances