Detergents, Cosmetics, Disinfectants, Pharma Chemicals

ETHYLENE GLYCOL MONOBUTYL ETHER
DESCRIPTION:

Ethylene glycol monobutyl ether is a primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a butoxy group.
Ethylene glycol monobutyl ether has a high-boiling (171℃) colourless liquid.
Ethylene glycol monobutyl ether is used as a solvent for paints and inks, as well as in some dry cleaning solutions.



CAS NUMBER: 111-76-2

MOLECULAR FORMULA: CH3(CH2)2CH2OCH2CH2OH

MOLECULAR WEIGHT: 118.17




DESCRIPTION:

Ethylene glycol monobutyl ether has a role as a protic solvent.
Ethylene glycol monobutyl ether is a primary alcohol and a glycol ether.
Ethylene glycol monobutyl ether is a natural product.
Ethylene glycol monobutyl ether appears as a colorless liquid with a mild, pleasant odor.

Ethylene glycol monobutyl ether is a colorless liquid with a mild, pleasant odor.
Ethylene glycol monobutyl ether has less dense than water.
Ethylene glycol monobutyl ether's flash point is 160°F.
Ethylene glycol monobutyl ether irritates skin and eyes.

Ethylene glycol monobutyl ether is used as a solvent and to make paints and varnish.
Ethylene glycol monobutyl ether is an organic compound with the chemical formula BuOC2H4OH (Bu = CH3CH2CH2CH2).
This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol.
As a relatively nonvolatile, inexpensive solvent, it is used in many domestic and industrial products because of its properties as a surfactant.

Ethylene glycol monobutyl ether can be obtained in the laboratory by performing a ring opening of 2-propyl-1,3-dioxolane with boron trichloride.
Ethylene glycol monobutyl ether offers numerous benefits in coating, ink, and cleaner applications.
Ethylene glycol monobutyl ether is an excellent solvent for many coatings resin types, including alkyd, phenolic, maleic, epoxy, and nitrocellulose resins.
Ethylene glycol monobutyl ether is an exceptional retarder solvent for lacquers, improving gloss and flow-out.

Ethylene glycol monobutyl ether is also widely used in amine-solubilized, water-based coatings because of its high flash point, complete water solubility, slow evaporation rate, low surface tension, and high coupling efficiency.
Ethylene glycol monobutyl ether is an effective coalescent that improves film integrity in both architectural and industrial maintenance latex paints.
Ethylene glycol monobutyl ether's unique combination of properties enables the effective removal of contaminants when used in Industrial & Institutional and/or household cleaners.

Ethylene glycol monobutyl ether is a clear, colourless, oily liquid with a unique sweet yet mild odour and has the formula C6H14O2.
Ethylene glycol monobutyl ether is a butyl ether of ethylene glycol and is miscible with water and common organic solvents.
Ethylene glycol monobutyl ether has been produced industrially for over half a century and is used primarily as a solvent in paints and surface coatings but also in inks and cleaning products.



APPLICATION:

-Aerosol coatings
-Aerospace coatings
-Architectural coatings
-Auto OEM
-Auto refinish
-Coil coatings
-Commerical printing inks
-Construction chemicals
-Fabric care
-Formulators
-Furniture
-Graphic arts
-Hard surface care
-Industrial cleaners
-Institutional cleaners
-Janitorial & household cleaners
-Lubricants
-Marine
-Oil or gas processing
-Paints & coatings
-Process solvents
-Protective coatings
-Rubber modification
-Soap/detergents
-Wood coatings



BENEFITS:

-Efficient coalescent
-Excellent coupling efficiency
-Good solvent activity
-High blush resistance
-Inert - Food use with limitations
-Inert - Nonfood use
-Low surface tension
-Miscible with water and most organic liquids
-Non-HAP
-REACH compliant
-Readily biodegradable
-Slow evaporation rate



PROPERTIES:

-Melting Point: -75 °C
-Boiling Point: 171 °C
-Flash point: 68 °C
-Specific Gravity (20/20): 0.90
-Refractive Index: 1.42
-Solubility in water: Completely miscible
-Solubility (miscible with): Alcohol, Ether, Benzene, Heptane, Acetone



PHYSICAL PROPERTIES:

-Boiling Point °C: 171.2
-Melting Point °C: -70.0
-Specific Gravity 20/20°C: 0.902
-Flash Point (closed cup) °C: 67.5



PHYSICAL AND CHEMICAL PROPERTIES:

-Density: 0.90 g/cm3 (20 °C)
-Explosion limit: 1.1 - 10.6 %(V)
-Flash point: 67 °C
-Melting Point: -75 °C
-pH value: 7 (H₂O, 20 °C) (as aqueous solution)
-Vapor pressure: 0.8 hPa (20 °C)
-Viscosity kinematic: 3.642 mm2/s (20 °C)
-Solubility: 900 g/l soluble



PROPERTIES:

-Molecular Weight: 118.17
-XLogP3: 0.8
-Hydrogen Bond Donor Count: 1
-Hydrogen Bond Acceptor Count: 2
-Rotatable Bond Count: 5
-Exact Mass: 118.099379685
-Monoisotopic Mass: 118.099379685
-Topological Polar Surface Area: 29.5 Ų
-Heavy Atom Count: 8
-Complexity: 37.5
-Isotope Atom Count: 0
-Defined Atom Stereocenter Count: 0
-Undefined Atom Stereocenter Count: 0
-Defined Bond Stereocenter Count: 0
-Undefined Bond Stereocenter Count: 0
-Covalently-Bonded Unit Count: 1
-Compound Is Canonicalized: Yes



SPECIFICATION:

-Assay (GC, area%): ≥ 99.0 % (a/a)
-Density (d 20 °C/ 4 °C): 0.900 - 0.901
-Water (K. F.): ≤ 0.20 %
-Peroxide (as H₂O₂): ≤ 0.05 %
-Identity (IR): passes test



STORAGE:

Store below +30°C.



SYNONYM:

2-Butoxyethanol
111-76-2
ETHYLENE GLYCOL MONOBUTYL ETHER
Butyl glycol
Butyl cellosolve
Butoxyethanol
n-Butoxyethanol
Ethanol, 2-butoxy
Ethylene glycol butyl ether
Butyl oxitol
Dowanol EB
Glycol butyl ether
Glycol ether eb
3-Oxa-1-heptanol
2-butoxyethan-1-ol
EGBE
2-Butoxy-1-ethanol
Gafcol EB
2-n-Butoxyethanol
O-Butyl ethylene glycol
Jeffersol eb
Butyl cellu-sol
BUCS
Ektasolve EB
Glycol monobutyl ether
Chimec NR
2-Butoxy ethanol
2-Butossi-etanolo
2-Butoxy-aethanol
Butylcelosolv
Butylglycol
Butoksyetylowy alkohol
2-Butoxy-ethanol
Ethylene glycol n-butyl ether
EGMBE
Monobutyl glycol etherMonobutyl ether of ethylene glycol
Ethylene glycol mono-n-butyl ethern-Butyl Cellosolve
.beta.-Butoxyethanol
ethyleneglycol monobutyl ether
Butyl monoether glycol
Butyglycol
Monobutyl ethylene glycol ethe
2-n-Butoxy-1-ethanol
Ether alcohol
Ethylene glycol, monobutyl ether
Butyl icinol
Minex BDH
NSC 60759
2-Hydroxyethyl n-butyl ether
2-Butoxyethanol (ethylene glycol monobutyl ether)
9004-77-7
Eter monobutilico del etilenglicol
I0P9XEZ9WV
Butyl 2-hydroxyethyl ether
Ether monobutylique de l'ethyleneglycol
DTXSID1024097
CHEBI:63921
NSC-60759
DTXCID904097
butylcellosolve
g lycol ether eb
beta-Butoxyethanol
2 -Butoxyethanol
CAS-111-76-2
SMR001253761
Butoxyethanol, 2-
Ektasolve EB solvent
CCRIS 5985
HSDB 538
Ek tasolve EB solvent
Glycol ether eb acetate
EINECS 203-905-0
UNII-I0P9XEZ9WV
UN2369
n-butoxyethanol sodium salt
EPA Pesticide Chemical Code 011501
BRN 1732511
Butyloxitol
AI3-0993
butoxy-ethanol
AI3-09903
Ethylene glycol mono butyl ether
Butyl Glycolether
EB Solvent
3-oxaheptan-1-ol
2-(n-Butoxy)ethanol
BuOCH2CH2OH
2-(1-Butyloxy) ethanol
EC 203-905-0
EC 500-012-0
Aethylenglycolmonobuthylaether
BUTOXYETHANOL [INCI]
2-Butoxy-aethanol(GERMAN)
SCHEMBL15712MLS002174253
MLS002454362
WLN: Q2O4
BUTYL CELLOSOLVE
Butyglycol(FRENCH, GERMAN
Ethylene glycol monobutyl ether
ethylene glycol-monobutyl ether
CHEMBL284588
QSPL 003
2-BUTOXYETHANOL
2-BUTOXYETHANOL
2-BUTOXY ETHANOL (ETHYLENE GLYCOL MONOBUTYL ETHER)
Ethylene glycol butyl ether, 99%
2-butoxyethanol
NSC60759
ZINC1690437
Tox21_202399
Tox21_300123
MFCD00002884
Ethylene glycol butyl ether, >=99%
AKOS009028760
NCGC00090683-01
NCGC00090683-02
NCGC00090683-03
NCGC00090683-04
NCGC00090683-05
NCGC00254083-01
NCGC00259948-01
LS-13220
B0698
FT-0626297
EN300-19317
Ethylene Glycol Monobutyl Ether Reagent Grade
C19355
Ethylene glycol butyl ether, analytical standard
ETHYLENE GLYCOL MONO-N-BUTYL ETHER
Q421557
Ethylene glycol butyl ether, for synthesis, 99.0%
J-508565
Ethylene glycol butyl ether, SAJ first grade, >=99.0%
Ethylene glycol butyl ether, spectrophotometric grade, >=99.0%



































ETHYLENE GLYCOL MONOSTEARATE
cas no 111-60-4 Glycol Monostearate ; Octadecanoic Acid, 1,2-Ethanediyl Ester; Ethylene Octadecanoate; 1,2-Ethanediyl Octadecanoate; Ethylene Glycol Monooctadecanoate; 2-Hydroxyethyl stearate;
ETHYLENE GLYCOL N-HEXYL ETHER
Ethylene glycol n-hexyl ether is a colorless liquid with a slight ether odor and bitter taste.
Ethylene glycol n-hexyl ether has the characteristic structure of glycol ethers and contains both ether and alcohol functional groups in the same molecule.
Ethylene glycol n-hexyl ether is a clear, mobile, neutral, slightly hygroscopic liquid with a mild odor.


CAS number: 112-25-4
EC number: 203-951-1
MDL Number: MFCD00045997
Molecular formula: C8H18O2


Ethylene glycol n-hexyl ether is a solvent that can be found in a variety of rust removers, hard surface cleaners and disinfectants.
Ethylene glycol n-hexyl ether, as known 2-Hexoxyethanol or 2-(Hexyloxy)ethanol, is a glycol ether that has a chemical formula of C8H18O2.
Ethylene glycol n-hexyl ether is miscible with all common solvents, e. g. alcohols, ketones, aldehydes, ethers, glycols and aromatic and aliphatic hydrocarbons.


Ethylene glycol n-hexyl ether is a colorless liquid with a slight ether-like odor and bitter taste.
Ethylene glycol n-hexyl ether's miscibility with water, however, is limited.
Ethylene glycol n-hexyl ether is a clear, mobile, neutral, slightly hygroscopic liquid with a mild odor.
As a result, Ethylene glycol n-hexyl ether provides unique cleaning power for removal of both water-soluble and greasy (water insoluble) soils.


Ethylene glycol n-hexyl ether (Ethylene Glycol Monohexyl Ether), n°112-25-4 is measured by GC-FID.
Ethylene glycol n-hexyl ether's vapour is heavier than air.
Since Ethylene glycol n-hexyl ether may react with the oxygen in the air to form peroxides.
Ethylene glycol n-hexyl ether (Cas No.: 112-25-4) is a high boiling pint, slow evaporating rate solvent with excellent solvency characteristics.


Ethylene glycol n-hexyl ether's miscibility with water, however, is limited.
Ethylene glycol n-hexyl ether has the characteristic structure of glycol ethers and contains both ether and alcohol functionalgroups in the same molecule.
Ethylene glycol n-hexyl ether is miscible with all common solvents, e. g. alcohols, ketones, aldehydes, ethers, glycols and aromatic and aliphatic hydrocarbons.


Ethylene glycol n-hexyl ether is a Glycol ether solvent.
n-Hexylglycol enters into the typical reactions of alcohols, e. g. esterification, etherification, oxidation and the formation of alcoholates.
Since Ethylene glycol n-hexyl ether may react with the oxygen in the air to form peroxides, BASF supplies it inhibited with 2,6-di-tert-butyl-para cresol (butylated hydroxytoluene – BHT).


Ethylene glycol n-hexyl ether enters into the typical reactions of alcohols, e. g. esterification, etherification, oxidation and the formation of alcoholates.
Ethylene glycol n-hexyl ether has the characteristic structure of glycol ethers and contains both ether and alcohol functional groups in the same molecule.


Ethylene glycol n-hexyl ether is a high boiling point, slow evaporating rate solvent with excellent solvency characteristics.
Ethylene glycol n-hexyl ether Solvent is a high boiling point, slow evaporating rate solvent with excellent solvencycharacteristics.
Ethylene glycol n-hexyl ether has a high boiling point, slow evaporating solvent with excellent solvency characteristics.



USES and APPLICATIONS of ETHYLENE GLYCOL N-HEXYL ETHER:
Ethylene glycol n-hexyl ether is used to break down soils and grease stains.
Ethylene glycol n-hexyl ether also serves as an intermediate for neopentanoate and hexyloxyethyl phosphate.
Ethylene glycol n-hexyl ether is used as a coalescing agent in latex paints and cleaners.
For instance, it improves the flow of many baking finish systems.


Ethylene glycol n-hexyl ether is used Industry, Scientific Research, Health, Environmental Protection, Agriculture.
Ethylene glycol n-hexyl ether plays an important role in speciality printing inks.
Ethylene glycol n-hexyl ether is used as a chemical intermediate for hexyloxyethyl phosphate and neopentanoate.
Ethylene glycol n-hexyl ether is used Clear, mobile, high-boiling, low-volatility liquid for use as a solvent, flow promoter and coalescent.


Ethylene glycol n-hexyl ether can be used as a solvent for paints, paints, resins, dyes, oils and lubricating oils, as well as coupling and dispersing agents.
By virtue of its good solvent power, the main applications of n-Hexylglycol are as a solvent, flow promoter and coalescent aid.
Ethylene glycol n-hexyl ether is used by professional workers (widespread uses), consumers, in re-packing or re-formulation, in manufacturing, and at industrial sites.


Other uses of Ethylene glycol n-hexyl ether are: Sealants, Adhesives, Coating products, Finger Paints, Fillers, Anti-freeze products, Plasters, Putties, Lubricants, Modelling Clay, Greases, Automotive care products, Machine wash liquids/detergents, Air fresheners, Fragrances, and Other outdoor use.
Ethylene glycol n-hexyl ether serves as a coalescing agent in cleaners and latex paints.


Ethylene glycol n-hexyl ether can also be used in printing inks and cleaners.
Ethylene glycol n-hexyl ether possesses high boiling point.
Usage of Ethylene glycol n-hexyl ether: Laboratory Reagents, Analytical Reagents, Diagnostic Reagents, Teaching Reagents


Ethylene glycol n-hexyl ether is mainly used as a solvent, flow promoter and coalescent aid in the coatings industry and in printing inks and cleaners.
Two solvents, Ethylene glycol n-hexyl ether and diethylene glycol hexyl ether, are potential replacements for halogenated hydrocarbons in non-vapor degreasing applications.


Ethylene glycol n-hexyl ether has excellent oil solubility, making it effective in household and industrial cleaning applications.
Ethylene glycol n-hexyl ether is used as solvent in specialty printing inks, coalescent for water-borne latex-based coatings, primary solvent in solvent-based silk screen printing inks.
Ethylene glycol n-hexyl ether is used as a coalescing agent in latex paints and cleaners.


Ethylene glycol n-hexyl ether can be used as a solvent in lacquers, paints, resins, dyes, oils and lubricants, as well as as a coupling and dispersant.
Ethylene glycol n-hexyl ether is used as a high-boiling solvent.
Ethylene glycol n-hexyl ether is used as special solvent for coating and ink.


Ethylene glycol n-hexyl ether is used as high-boiling solvent.
Ethylene glycol n-hexyl ether is used as a chemical intermediate for hexyloxyethyl phosphate and neopentanoate.
Ethylene glycol n-hexyl ether is used as solvents in speciality printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.


As a result, Ethylene glycol n-hexyl ether provides unique cleaning power for removal of both water-soluble andgreasy (water insoluble) soils.
Ethylene glycol n-hexyl ether can be used as solvent in specialty printing inks.
Ethylene glycol n-hexyl ether plays an important role in specialty printing inks. Because of its limited water solubility andslow evaporation.
Ethylene glycol n-hexyl ether exhibits very good solvency, superior oil solubility, and slow evaporation rate.


Ethylene glycol n-hexyl ether is used for Biological Purpose, For Microscopic Purpose, For Lens Blooming, Technical Grade, Pratical Use, Pro Analysis, Super Special Grade, For Synthesis, For Electrophoresis Use.
Ethylene glycol n-hexyl ethercan be used as coupling agent and solvent in household and industrial clearners, rust removers, hard surface cleaners and disinfectants.


Ethylene glycol n-hexyl ether can be used as coalescent for water-borne.
The linear hexyl portion of this provides excellent oil solubility characteristics that make Ethylene glycol n-hexyl ether useful in both consumer and industrial cleaner applications.
Added in small proportions to formulations for electrodeposition paints, it greatly improves film formation and levelling.


Ethylene glycol n-hexyl ether is also eminently suitable as a mild, low-odour co-solvent in low-aromatic mineral spirit blends for dissolving polymer binders such as Acronal 260 F.
Ethylene glycol n-hexyl ether is mainly used as solvents for cleaning fluids, paints, coatings and ink preparations.


Ethylene glycol n-hexyl ether is used as high-boiling solvent, Solvents (which become part of product formulation or mixture), and Cleaning and furnishing care products.
Because of its limited water solubility and slow evaporation, Ethylene glycol n-hexyl ether can be used in formulations for the silk screen process to prevent premature setting of the ink.


Ethylene glycol n-hexyl ether is used as a coalescing agent for water-based latex-based coatings and plays an important role in specialty printing inks, including screen printing processes, where its limited water solubility and slow evaporation rate prevent premature ink settling.
Ethylene glycol n-hexyl ether is used as solvents in specialty printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.


The linear hexyl portion of Ethylene glycol n-hexyl ether provides excellent oilsolubility characteristics that make it useful in both consumer and industrial cleaner applications.
Ethylene glycol n-hexyl ether can be used in formulations for the silk screen process to prevent premature setting of the ink.
Ethylene glycol n-hexyl ether can be used as primary solvent in solvent-based silk screen printing inks.


Ethylene glycol n-hexyl ether is used as solvents in specialty printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.
Ethylene glycol n-hexyl ether is used as a high-boiling solvent.


-Applications of Ethylene glycol n-hexyl ether:
• Specialty printing inks
• Coalescent for water-borne, latex-based coatings, coupling agent and solvent in household and industrial cleaners, rust removers, hard surface cleaners, and disinfectants
• Primary solvent in solvent-based silk screen printing inks


-Uses of Ethylene glycol n-hexyl ether:
*Cosmetics
*Cleaners
*Textiles
*Waterborne coatings
*Cleaning
*Printing ink



ALTERNATIVE PARENTS of ETHYLENE GLYCOL N-HEXYL ETHER:
*Primary alcohols
*Hydrocarbon derivatives



SUBSTITUENTS of ETHYLENE GLYCOL N-HEXYL ETHER:
*Dialkyl ether
*Hydrocarbon derivative
*Primary alcohol
*Alcohol
*Aliphatic acyclic compound



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENE GLYCOL N-HEXYL ETHER:
Molar mass 146.23 g/mol
n-Hexylglycol: 98.0 min. %
Water: 0.1 max. %
Pt/Co color value (Hazen): 10 max.
Acid value: 0.1 max mg KOH/g
Boiling range at 1013 hPa; 95 Vol.-%; 2 – 97 ml 200 – 212 °C
Density at 20 °C: 0.887 – 0.890 g/cm3
Refractive index: nD20 1.428 – 1.430
Solidification point: at 1013 hPa - 42 °C (ice flakes)
Evaporation rate ether: 1 approx. 1200
Enthalpy of combustion: at 25 °C 33 136 kJ/kg -
Enthalpy of vaporization: at 25 °C 475 kJ/kg -
Enthalpy of vaporization: at boiling point 325 kJ/kg
Enthalpy of formation: at 25 °C - 3 776 kJ/kg -

Dipole moment: (µ) 2.08 D
Solubility Mass fraction of Hexyl glycol in water: 1.0 %
Water in Hexyl glycol: 18.8 %
Water Solubility: 4.22 g/L
logP: 1.82
logP: 1.65
logS: -1.5
pKa (Strongest Acidic): 15.12
pKa (Strongest Basic): -2.7
Physiological Charge: 0
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 1
Polar Surface Area: 29.46 Ų
Rotatable Bond Count: 7

Refractivity: 42.38 m³·mol⁻¹
Polarizability: 18.54 ų
Number of Rings: 0
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: Yes
Veber's Rule: Yes
MDDR-like Rule: Yes
S.G @ 20C/20C: 0.887
Distillation Range C Min: 200
Distillation Range C Max: 212
Evaporation Rate Ether = 1: >1200
Flash Point Deg C: 92
Solubility % wt in Water: @ 20C 1

Appearance and properties: transparent liquid
Density: 0.888 g/mL at 20 °C(lit.)
Boiling point: 98-99°C 0,15mm
Melting point: -45.1ºC
Flash point: 98-99°C/0.15mm
Refractive index: n20/D 1.431
Appearance: Colorless Clear Liquid
Content, GC%Wt: ≥98.0
Acidity,%Wt.(calculated as acetic acid): ≤0.01
Moisture,%Wt: ≤0.15
Chroma, Hazen unit (platinum-cobalt color number): ≤15
Min. Purity Spec: >99% (GC)
Physical Form (at 20°C): Liquid
Melting Point: -42°C

Boiling Point: 208°C
Flash Point: 94°C
Density: 0.89
Refractive Index: 1.43
Long-Term Storage: Store long-term in a cool, dry place
Appearance Form: liquid
Color: colorless
Odor: ether-like
Odor Threshold: No data available
pH: No data available
Melting point/freezing point:
Melting point/range: -50,1 °C at 1.013 hPa
Initial boiling point and boiling range: 208,5 °C at 1.013 hPa

Flash point: 90 °C - closed cup
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: 0,1 hPa at 22,9 °C - OECD Test Guideline 104
Vapor density: No data available
Density: 0,888 g/mL at 20 °C
Relative density: No data available
Water solubility: 9,46 g/l - soluble
Partition coefficient: n-octanol/water:
log Pow: 1,97 at 25 °C
Autoignition temperature: 225 °C at 1.008 - 1.015 hPa
Decomposition temperature: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 4,4 mPa.s at 20 °C
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Appearance (20°)C : Clear Liquid
Color (APHA or less) : 15
Specific gravity (20°C) : 0.887~0.892
Acidity (% or less) : 0.01
Water content (% or less) : 0.2
Purity (% or more) : 98
Molecular Weight: 146.23
XLogP3: 1.9

Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 7
Exact Mass: 146.130679813
Monoisotopic Mass: 146.130679813
Topological Polar Surface Area: 29.5 Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 55.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes


FIRST AID MEASURES of ETHYLENE GLYCOL N-HEXYL ETHER:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing: make victim drink water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ETHYLENE GLYCOL N-HEXYL ETHER:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up carefully with liquid-absorbent material.
Dispose of properly.



FIRE FIGHTING MEASURES of ETHYLENE GLYCOL N-HEXYL ETHER:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENE GLYCOL N-HEXYL ETHER:
-Control parameters
--Ingredients with workplace control parameters
-Exposure controls
--Personal protective equipment
*Eye/face protection
Use equipment for eye protection.
Tightly fitting safety goggles.
*Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Wash and dry hands.
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ETHYLENE GLYCOL N-HEXYL ETHER:
-Precautions for safe handling:
*Hygiene measures:
Immediately change contaminated clothing.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store under inert gas.



STABILITY and REACTIVITY of ETHYLENE GLYCOL N-HEXYL ETHER:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available



SYNONYMS:
2-(Hexyloxy)ethanol
112-25-4
Ethylene glycol monohexyl ether
2-Hexyloxyethanol
Ethanol, 2-(hexyloxy)-
2-HEXOXYETHANOL
Hexyl cellosolve
n-Hexyl cellosolve
Glycol monohexyl ether
Cellosolve, N-hexyl-
2-Hexyloxy-1-ethanol
Ethylene glycol n-hexyl ether
2-n-(Hexyloxy)ethanol
7P0O8282NR
Ethylene glycol mono-n-hexyl ether
DSSTox_CID_6908
DSSTox_RID_78248
2-(hexyloxy)ethan-1-ol
DSSTox_GSID_26908
31726-34-8
Ethanol, 2-hexyloxy-
CAS-112-25-4
Ethylene glycol-n-monohexyl ether
HSDB 5569
EINECS 203-951-1
Hexyl alcohol, ethoxylated
BRN 1734691
UNII-7P0O8282NR
2-hexyloxy-ethanol
MFCD00045997
2-(n-Hexyloxy)ethanol
Ethylenglykolmonohexylether
2-(1-Hexyloxy) ethanol
EC 203-951-1
Ethylene glycol hexyl ether
SCHEMBL24741
4-01-00-02383 (Beilstein Handbook Reference)
CHEMBL3188016
DTXSID1026908
Poly(oxy-1,2-ethanediyl), .alpha.-hexyl-.omega.-hydroxy-
ZINC2041054
Tox21_202105
Tox21_300545
AKOS009156771
NCGC00248089-01
NCGC00248089-02
NCGC00254448-01
NCGC00259654-01
LS-13544
DB-041064
FT-0631642
H0343
EN300-114321
F71224
W-109065
Q27268660
Ethylene glycol monohexyl ether, BioXtra, >=99.0% (GC)
2-(Hexyloxy)ethanol
Hexylglycol
2-(HEXYLOXY)ETHANOL
2-N-(HEXYLOXY)ETHANOL
C6E1
ETHYLENE GLYCOL MONOHEXYL ETHER
ETHYLENE GLYCOL MONO-N-HEXYL ETHER
ETHYLENE GLYCOL N-HEXYL ETHER
HEXYLGLYCOL
N-HEXYL CELLOSOLVE
N-HEXYLMONOOXYETHYLENE
2-(hexyloxy)-ethano
2-Hexoxyethanol
2-hexyloxy-ethano
Cellosolve, n-hexyl-
ethyleneglycol-n-monohexylether
Glycol monohexyl ether
glycolmonohexylether
Hexyl cellosolve
hexylcellosolve
n-hexyl-cellosolv
Ethylenegylcolmono-N-hexylether
2-(Hexyloxy)ethanol
Ethylene glycol monohexyl ether
2-Hexyloxyethanol
Ethanol, 2-(hexyloxy)-
2-HEXOXYETHANOL
Hexyl cellosolve
n-Hexyl cellosolve
Glycol monohexyl ether
Cellosolve, N-hexyl-
2-Hexyloxy-1-ethanol
Ethylene glycol n-hexyl ether
2-n-(Hexyloxy)ethanol
7P0O8282NR
Ethylene glycol mono-n-hexyl ether
DSSTox_CID_6908
DSSTox_RID_78248
DSSTox_GSID_26908
31726-34-8
Ethanol, 2-hexyloxy-
Ethylene glycol-n-monohexyl ether
HSDB 5569
Hexyl alcohol, ethoxylated
BRN 1734691
UNII-7P0O8282NR
2-hexyloxy-ethanol
MFCD00045997
2-(n-Hexyloxy)ethanol
Ethylenglykolmonohexylether
2-(1-Hexyloxy) ethanol
EC 203-951-1
Ethylene glycol hexyl ether
SCHEMBL24741
4-01-00-02383
CHEMBL3188016
DTXSID1026908
Poly(oxy-1,2-ethanediyl), .alpha.-hexyl-.omega.-hydroxy-
ZINC2041054
Tox21_202105
Tox21_300545
AKOS009156771
NCGC00248089-01
NCGC00248089-02
NCGC00254448-01
NCGC00259654-01
LS-13544
DB-041064
FT-0631642
H0343
F71224
W-109065
Q27268660
Ethylene glycol monohexyl ether, BioXtra, >=99.0% (GC)
2-(Hexyloxy)ethanol
Cellosolve, n-hexyl-
Ethanol, 2-hexyloxy-
Ethylene glycol monohexyl ether
Ethylene glycol n-hexyl ether
Ethylene glycol-n-monohexyl ether
Glycol monohexyl ether
Hexyl cellosolve
n-Hexyl cellosolve
C6E1
HEXYLGLYCOL
2-hexyloxyethanol
N-HEXYL CELLOSOLVE
2-(hexyloxy)-ethano
N-HEXYLMONOOXYETHYLENE
ETHYLENE GLYCOL N-HEXYL ETHER
ETHYLENE GLYCOL MONOHEXYL ETHER
ETHYLENE GLYCOL MONO-N-HEXYL ETHER
2-(Hexyloxy)ethanol;2-HEXOXYETHANOL
AC1L1QF7
AC1Q7D9E
Cellosolve, N-hexyl-
EGHE
Ethanol, 2-(hexyloxy)-
Ethanol, 2-hexyloxy-
Ethylene glycol monohexyl ether
Ethylene glycol n-hexyl ether
Ethylene glycol-n-monohexyl ether
Glycol monohexyl ether
H0343
Hexyl alcohol, ethoxylated
Hexyl cellosolve
Hexyl poly(oxyethylene) ether
Hexylglycol
Poly(oxy-1,2-ethanediyl), alpha-hexyl-omega-hydroxy-
SBB060173
alpha-Hexyl,omega-hydroxypoly(oxy-1,2-ethanediyl)
n-Hexyl cellosolve
2- (HEXYLOXY) ETHANOL
2-N-(HEXYLOXY) ETHANOL
C6E1
ETHYLENE GLYCOL MONOHEXYL ETHER
ETHYLENE GLYCOL MONO-N-HEXYL ETHER
ETHYLENE GLYCOL N-HEXYL ETHER
HEXYL GLYCOL
N-HEXYL CELLOSOLVE
N-HEXYLMONOOXYETHYLENE
2-(hexyloxy)-ethane
2-Hexoxyethanol
2-hexyloxy-ethano
Cell fluid, n-hexyl-
ethylene glycol-n-monohexyl ether
Glycol monohexyl ether
glycol monohexyl ether
Hexyl cellosolvation
hexyl cellosolve
n-hexyl-cellosolv
Ethylene gyl carbon mono-N-hexyl ether
Diethylene glycol hexyl ether
2-((2-Hexyloxy)ethoxy)ethanol
Diethylene glycol mono(n-hexyl) ether
Hexol carbitol
Diethylene glycol monohexyl ether
n-Hexoxyethoxyethanol
n-Hexyl carbitol
2-((2-Hexyloxy)ethoxy)ethanol
2-(2-(hexyloxy)ethoxy)ethanol


ETHYLENE GLYCOL N-HEXYL ETHER
Ethylene glycol n-hexyl ether is a high boiling pint, slow evaporating rate solvent with excellent solvency characteristics.
Ethylene glycol n-hexyl ether is typically a clear, colorless liquid with a characteristic mild odor.
Ethylene glycol n-hexyl ether is miscible with water and many organic solvents.

CAS Number: 112-25-4
Molecular Formula: C8H18O2
Molecular Weight: 146.23
EINECS Number: 203-951-1

Ethylene glycol n-hexyl ether is used by professional workers (widespread uses), consumers, in re-packing or re-formulation, in manufacturing, and at industrial sites.
Ethylene glycol n-hexyl ether is used as high-boiling solvent.
Ethylene glycol n-hexyl ether also serves as an intermediate for neopentanoate and hexyloxyethyl phosphate.

Ethylene glycol n-hexyl ether serves as a coalescing agent in cleaners and latex paints.
Ethylene Glycol n-Hexyl Ether's molecular formula is C8H18O2 or C6H13OCH2CH2OH.
Ethylene Glycol n-Hexyl Ether is a high boiling pint, slow evaporating rate solvent with excellent solvency characteristics.

Ethylene glycol n-hexyl ether is an oily colorless liquid with a mild sweet odor.
Ethylene glycol n-hexyl ether, also known as 1,6-Hexanediol, is a chemical compound with the molecular formula C6H14O2.
Ethylene glycol n-hexyl ether is a glycol in which the two hydroxy groups are at positions 2 and 4 of 2-methylpentane (isopentane).

Ethylene Glycol n-Hexyl Ether or 2-(Hexyloxy)ethanol is a glycol ether.
Ethylene Glycol n-Hexyl Ether has a chemical formula of C6H14O2.
Ethylene Glycol n-Hexyl Ether is used as solvents in specialty printing inks and coalescing aids in surface coatings.

The chemical structure consists of a hexyl chain (a six-carbon linear alkyl group) attached to the oxygen atom of an ethylene glycol molecule.
Ethylene Glycol n-Hexyl Ether floats and mixes slowly with water.
Ethylene Glycol n-Hexyl Ether belongs to the class of diols, which are organic compounds containing two hydroxyl (-OH) groups.

The "n" in N-Hexyl Glycol indicates that the carbon chain is linear.
Ethylene Glycol n-Hexyl Ether is a clear, mobile, neutral, slightly hygroscopic liquid with a mild odor.
Ethylene Glycol n-Hexyl Ether is miscible with all common solvents, e. g. alcohols, ketones, aldehydes, ethers, glycols and aromatic and aliphatic hydrocarbons.

Ethylene Glycol n-Hexyl Ether's miscibility with water, however, is limited.
Ethylene Glycol n-Hexyl Ether enters into the typical reactions of alcohols, e. g. esterification, etherification, oxidation and the formation of alcoholates.
Since Ethylene Glycol n-Hexyl Ether may react with the oxygen in the air to form peroxides, BASF supplies it inhibited with 2.6-di-tert-butyl-paracresol Ethylene Glycol n-Hexyl Ether is as a solvent for coatings and degreasing.

Ethylene Glycol n-Hexyl Ether is mainly used as a solvent, flow promoter and coalescent aid in the coatings industry.
Ethylene Glycol n-Hexyl Ether is often referred to by common names such as hexyl cellosolve or hexyl glycol ether.
Ethylene Glycol n-Hexyl Ether finds applications in various industries, including coatings, paints, cleaning products, and as a solvent in different formulations.

Ethylene Glycol n-Hexyl Ether exhibits solvent properties, making it useful in formulations where solubility and dispersing properties are required.
Ethylene Glycol n-Hexyl Ether is commonly used as a solvent in the formulation of coatings and paints, where it aids in achieving the desired viscosity and flow properties.
Ethylene Glycol n-Hexyl Ether may be included in the formulation of cleaning products, such as degreasers and industrial cleaners.

Ethylene Glycol n-Hexyl Ether can be employed as a solvent in the production of inks, contributing to the dispersion of pigments and other ink components.
Ethylene Glycol n-Hexyl Ether is utilized in surface coatings for its ability to improve film formation and enhance the quality of the coating.
Ethylene Glycol n-Hexyl Ether may be used in certain chemical reactions or processes where its unique chemical properties are beneficial.

Ethylene Glycol n-Hexyl Ether is important to handle ethylene glycol n-hexyl ether with care and follow safety guidelines.
This includes using appropriate personal protective equipment and ensuring proper ventilation in areas where it is used.
Ethylene Glycol n-Hexyl Ether is used in printing inks and cleaners.

Ethylene Glycol n-Hexyl Ether is an oxygenated solvent derived from acetone which has two alcohol functions.
Ethylene Glycol n-Hexyl Ether has a low evaporation rate and it is completely miscible with water.
Ethylene Glycol n-Hexyl Ether is mainly used as a solvent or coupling agent.

Ethylene Glycol n-Hexyl Ether is a potential substitute for glycol ethers.
Ethylene Glycol n-Hexyl Ether is also an effective shrinkage reduction admixture or SRA for concrete and mortar.
Ethylene Glycol n-Hexyl Ether is often used in cosmetics and personal care products for its moisturizing properties.

Ethylene Glycol n-Hexyl Ether can contribute to the hydration of the skin when included in formulations such as creams and lotions.
In the flavor and fragrance industry, Ethylene Glycol n-Hexyl Ether can be utilized as a carrier for certain flavors and fragrances.
Ethylene Glycol n-Hexyl Ether is mild odor and solvency make it suitable for use in these applications.

Ethylene Glycol n-Hexyl Ether can be esterified with various acids to produce specific esters.
Esters derived from Ethylene Glycol n-Hexyl Ether may find use in different industries, including the fragrance and flavor industry.
Ethylene Glycol n-Hexyl Ether has been used historically in the production of photographic chemicals.

Ethylene Glycol n-Hexyl Ether also can be used as a coupling agent, rust remover, adhesives and surface cleaners.
Ethylene glycol n-hexyl ether, also known as hexyl cellosolve or hexyl glycol ether, is a chemical compound belonging to the family of glycol ethers.
Ethylene Glycol n-Hexyl Ether is characterized by having a six-carbon linear alkyl chain (hexyl) and an ethylene glycol moiety.

Ethylene Glycol n-Hexyl Ether is soluble in alcohol and ether, water (9.46 g/L ).
Ethylene Glycol n-Hexyl Ether is used as solvents in speciality printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.
Ethylene Glycol n-Hexyl Ether is used as solvent in specialty printing inks, coalescent for water-borne latex-based coatings, primary solvent in solvent-based silk screen printing inks.

Ethylene Glycol n-Hexyl Ether possesses high boiling point.
Ethylene Glycol n-Hexyl Ether exhibits very good solvency, superior oil solubility, and slow evaporation rate.
Ethylene Glycol n-Hexyl Ether is a solvent.

Ethylene Glycol n-Hexyl Ether can be found in a variety of rust removers, hard surface cleaners and disinfectants.
Ethylene Glycol n-Hexyl Ether is used to break down soils and grease stains.
Ethylene Glycol n-Hexyl Ether or 2-(Hexyloxy)ethanol is a glycol ether.

Ethylene Glycol n-Hexyl Ether is used as solvents in specialty printing inks and coalescing aids in surface coatings.
Ethylene Glycol n-Hexyl Ether might be included in the formulation of adhesives and sealants, contributing to the viscosity and performance of these products.
Ethylene Glycol n-Hexyl Ether may be used in the textile industry, where it can aid in the solubilization and application of dyes and other chemicals.

Ethylene Glycol n-Hexyl Ether could be used in formulations for cleaning and degreasing metals in industrial processes.
In the woodworking industry, ethylene glycol n-hexyl ether might be included in wood stains and finishes to improve application properties.
Ethylene Glycol n-Hexyl Ether also can be used as a rust remover.

Ethylene Glycol n-Hexyl Ether is used as solvents in speciality printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.
Ethylene Glycol n-Hexyl Ether is used as high-boiling solvent.
Ethylene Glycol n-Hexyl Ether also serves as an intermediate for hexyloxyethyl phosphate.

Ethylene Glycol n-Hexyl Ether is miscible with water, soluble in ethanol, and soluble in most organic solvents.
Ethylene Glycol n-Hexyl Ether is an oily colorless liquid with a mild sweet odor.
Ethylene Glycol n-Hexyl Ether floats and mixes slowly with water.

Ethylene Glycol n-Hexyl Ether is a glycol in which the two hydroxy groups are at positions 2 and 4 of 2-methylpentane (isopentane).
Ethylene Glycol n-Hexyl Ether is a clear, mobile, neutral, slightly hygroscopic liquid with a mild odor.
Ethylene Glycol n-Hexyl Ether is miscible with all common solvents, e. g. alcohols, ketones, aldehydes, ethers, glycols and aromatic and aliphatic hydrocarbons.

Ethylene Glycol n-Hexyl Ether may be utilized in the formulation of hydraulic brake fluids.
Ethylene Glycol n-Hexyl Ether is properties can contribute to the fluid's ability to transfer pressure and resist high temperatures in braking systems.
In the oil and gas industry, Ethylene Glycol n-Hexyl Ether might be used in the formulation of certain chemicals for oilfield applications, such as drilling fluids or completion fluids.

Ethylene Glycol n-Hexyl Ether can be employed in the formulation of coolants for various cooling systems, helping to maintain proper thermal conditions in industrial processes or automotive engines.
Ethylene Glycol n-Hexyl Ether may serve as a solvent in the pharmaceutical industry for certain drug formulations where its properties are beneficial.
Ethylene Glycol n-Hexyl Ether might be used as a catalyst or co-catalyst in organic synthesis reactions, facilitating specific chemical transformations.

In the field of hydraulic fracturing (fracking), Ethylene Glycol n-Hexyl Ether may find applications in the formulation of fracking fluids used to fracture rocks and extract natural gas or oil.
Ethylene Glycol n-Hexyl Ether can be incorporated into water treatment formulations for cooling towers to prevent scale formation and corrosion.
Ethylene Glycol n-Hexyl Ether's miscibility with water, however, is limited.

Ethylene Glycol n-Hexyl Ether enters into the typical reactions of alcohols, e. g. esterification, etherification, oxidation and the formation of alcoholates.
As a result, Ethylene Glycol n-Hexyl Ether provides unique cleaning power for removal of both water-soluble and greasy (water insoluble) soils.
The linear Ethylene Glycol n-Hexyl Ether portion of this provides excellent oil solubility characteristics that make it useful in both consumer and industrial cleaner applications.

Ethylene Glycol n-Hexyl Ether plays an important role in specialty printing inks.
Because of its limited water solubility and slow evaporation, it can be used in formulations for the silk screen process to prevent premature setting of the ink

Melting point: -45.1℃
Boiling point: 98-99°C 0,15mm
Density: 0.888 g/mL at 20 °C(lit.)
vapor pressure: 10Pa at 20℃
refractive index: n20/D 1.431
Flash point: 98-99°C/0.15mm
storage temp.: -15°C
pka: 14.44±0.10(Predicted)
form: clear liquid
color: Colorless to Light yellow
Water Solubility: Soluble in alcohol and ether, water (9.46 g/L ).
BRN: 1734691
LogP: 1.97 at 25℃

Ethylene glycol n-hexyl ether is considered a VOC, and its use is regulated in certain applications due to environmental and air quality concerns.
In some regions, there are limits on the allowable VOC content in certain consumer products.
Ethylene Glycol n-Hexyl Ether may have film-forming properties, which can be beneficial in applications where the formation of a protective or decorative film is desired, such as in coatings and paints.

Similar to other glycol ethers, ethylene glycol n-hexyl ether may have hygroscopic properties, meaning it can absorb moisture from the air.
Ethylene Glycol n-Hexyl Ether can be used as a chemical intermediate in the synthesis of other compounds.
Some chemical reactions may involve the use of ethylene glycol n-hexyl ether as a starting material.

Due to its solvency, it may find applications in industrial cleaning processes, particularly in formulations designed to remove oils, greases, and other contaminants.
Ethylene Glycol n-Hexyl Ether is an oxygenated solvent derived from acetone which has two alcohol functions.
Ethylene Glycol n-Hexyl Ether is used as a reagent in the synthesis of functionalized boronic esters.

Ethylene Glycol n-Hexyl Ether is used in laboratory studies as a precipitant and cryoprotectant in protein crystallography.
Ethylene Glycol n-Hexyl Ether may find applications in heat transfer fluids, helping to transfer heat efficiently in various industrial processes.
Ethylene Glycol n-Hexyl Ether may be used in analytical chemistry as a solvent or as a component in certain analytical methods.

Ethylene Glycol n-Hexyl Ether is a member of the glycol ether family, which includes various compounds used in different industries for their solvency, stability, and other properties.
Ethylene Glycol n-Hexyl Ether also used in the preparation of vinylboronates.
Ethylene Glycol n-Hexyl Ether is mainly used as a coupling agent and an additive to hydraulic fluids, inks and cement.

Ethylene Glycol n-Hexyl Ether can also be used as a building block in chemical synthesis.
Ethylene Glycol n-Hexyl Etheris also employed as a blood volume expander.
Ethylene Glycol n-Hexyl Ether can be used in formulations for the silk screen process to prevent premature setting of the ink.

Ethylene Glycol n-Hexyl Ether may be used in the tire manufacturing industry as a component in adhesives for tire cord, contributing to the bonding properties of the adhesive.
Ethylene Glycol n-Hexyl Ether may be employed as an antioxidant in fuel formulations to help prevent degradation and improve the stability of the fuel.
Ethylene Glycol n-Hexyl Ether might be considered as a component in wood preservatives, helping to protect wood from decay and insect damage.

Ethylene Glycol n-Hexyl Ether may find applications in the production of materials used in the photovoltaic (solar cell) industry.
Ethylene Glycol n-Hexyl Ether may be used in research and development activities, particularly in laboratories exploring new formulations or chemical processes.
Ethylene Glycol n-Hexyl Ether can be employed in the polymer industry as a component in the synthesis of certain polymers.

Ethylene Glycol n-Hexyl Ether is inclusion may impart specific properties to the resulting polymer.
Ethylene glycol n-hexyl ether might find applications in the automotive industry, such as in the formulation of automotive coatings or cleaning products.
Due to its solvency and film-forming properties, it may be used in the formulation of floor polishes and waxes.

Ethylene Glycol n-Hexyl Ether could be included in formulations for ink removers or cleaning agents designed to remove ink stains.
In the textile printing industry, ethylene glycol n-hexyl ether may be used in ink formulations for printing on fabrics.
Ethylene Glycol n-Hexyl Ether might be used in the formulation of aerosol products, such as spray paints or coatings.

Ethylene Glycol n-Hexyl Ether is generally considered to be biodegradable.
Biodegradability is an important factor in assessing the environmental impact of a chemical.
Ethylene Glycol n-Hexyl Ether could be used in the production of resins, contributing to the overall characteristics of the resin.

Ethylene glycol n-hexyl ether may be employed in the formulation of certain hydraulic fluids, contributing to their lubricating properties.
In the field of inkjet printing, it may find applications in ink formulations for use in inkjet printers.

Ethylene Glycol n-Hexyl Ether is solvency properties make it suitable for use in formulations for metal degreasers, which are used to remove oils and greases from metal surfaces.
In laboratory settings, Ethylene Glycol n-Hexyl Ether might be used as a solvent or as a component in specific experimental setups.

Uses:
Ethylene Glycol n-Hexyl Ether is used as solvents in speciality printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.
Ethylene Glycol n-Hexyl Ether is used by professional workers (widespread uses), consumers, in re-packing or re-formulation, in manufacturing, and at industrial sites.
Ethylene Glycol n-Hexyl Ether is used as high-boiling solvent.

Ethylene Glycol n-Hexyl Ether also serves as an intermediate for neopentanoate and hexyloxyethyl phosphate.
Ethylene Glycol n-Hexyl Ether serves as a coalescing agent in cleaners and latex paint.
Ethylene Glycol n-Hexyl Ether can be used as solvent in specialty printing inks.

Ethylene Glycol n-Hexyl Ether can be used as coalescent for water-borne
Ethylene Glycol n-Hexyl Ether can be used as solvent in specialty printing inks.
Ethylene Glycol n-Hexyl Ether can be used as coalescent for water-borne.

Ethylene Glycol n-Hexyl Ether can be used as coupling agent and solvent in household and industrial clearners, rust removers, hard surface cleaners and disinfectants.
Ethylene Glycol n-Hexyl Ether is a fine chemical product with a wide range of uses, which can be used in pesticides, biochemical engineering, photosensitive materials, synthetic fragrances and other fields.
Ethylene Glycol n-Hexyl Ether is a highly soluble high-grade organic solvent.

Ethylene Glycol n-Hexyl Ether can be used as an additive in the production of metal surface treatment agents for rust and oil removal.
Ethylene Glycol n-Hexyl Ether can also be used as a textile auxiliaries, as well as coatings and latex paints.
Ethylene Glycol n-Hexyl Ether can also be used in cosmetics, as a pesticide stabilizer, but also as a daily chemical moisturizer, flavor and fragrance raw materials, hydraulic oil, high-temperature lubricating oil, brake oil, dry cleaning agent, printing ink, pigment dispersant, wood preservative etc.

Ethylene Glycol n-Hexyl Ether can be used as primary solvent in solvent-based silk screen printing inks.
Ethylene Glycol n-Hexyl Ether is used as a solvent in the formulation of coatings and paints to improve viscosity, flow, and film-forming properties.
Included in industrial cleaners and degreasers due to its solvency, helping to remove oils, greases, and contaminants.

Ethylene Glycol n-Hexyl Ether employed as a solvent in the production of inks for various printing applications, such as inkjet printing and textile printing.
Ethylene Glycol n-Hexyl Ether found in automotive coatings, cleaning products, and formulations where its solvent properties are beneficial.
Included in the formulation of adhesives and sealants, contributing to viscosity and performance.

Ethylene Glycol n-Hexyl Ether is used in the production of floor polishes and waxes, where it helps in achieving a smooth and protective finish.
Applied in the textile industry for solubilizing dyes and other chemicals used in fabric treatments.
Ethylene Glycol n-Hexyl Ether found in the formulation of aerosol products, including spray paints and coatings.

Ethylene Glycol n-Hexyl Ether is used in industrial processes for cleaning and degreasing metal surfaces.
Ethylene Glycol n-Hexyl Ether may find applications in the production of materials used in the photovoltaic (solar cell) industry.
Ethylene Glycol n-Hexyl Ether is used as a component in the synthesis of certain polymers, contributing specific properties to the final polymer.

Included in the formulation of hydraulic fluids or other automotive fluids where its properties are beneficial.
Ethylene Glycol n-Hexyl Ether employed in woodworking for improving the application properties of wood stains and finishes.
Ethylene Glycol n-Hexyl Ether is used in formulations for ink removers or cleaning agents designed to remove ink stains.

Ethylene Glycol n-Hexyl Ether found in ink formulations for textile printing on fabrics.
Considered biodegradable, making it suitable for applications where environmental impact is a concern.
Ethylene Glycol n-Hexyl Ether is used in the production of resins, contributing to the characteristics of the resin.
Hydraulic Fluids:

Ethylene Glycol n-Hexyl Ether is used in formulations for metal degreasers to remove oils and greases from metal surfaces.
Ethylene Glycol n-Hexyl Ether is used in laboratories as a solvent or a component in specific experimental setups where its properties are advantageous.
Ethylene Glycol n-Hexyl Ether may be utilized as a component in fuel additives to enhance stability and performance.

Ethylene Glycol n-Hexyl Ether found in the formulation of coolants and heat transfer fluids where it helps maintain proper thermal conditions.
Ethylene Glycol n-Hexyl Ether included as a component in wood preservatives to protect wood from decay and insect damage.
Ethylene Glycol n-Hexyl Ether is used in the production of surfactants where its properties contribute to the stability of emulsions or foams.

Ethylene Glycol n-Hexyl Ether is used in the formulation of deicing fluids, particularly in applications where prevention of ice formation is crucial.
Included as an additive in concrete formulations to improve workability and setting time.
Utilized in the oil and gas industry for the formulation of certain chemicals used in oilfield applications.

Ethylene Glycol n-Hexyl Ether may be used in the formulation of hydraulic brake fluids for automotive applications.
Ethylene Glycol n-Hexyl Ether is used as a reagent in the synthesis of functionalized boronic esters.
Ethylene Glycol n-Hexyl Ether is used in laboratory studies as a precipitant and cryoprotectant in protein crystallography.

Ethylene Glycol n-Hexyl Ether is used as a carrier for certain flavors and fragrances in the flavor and fragrance industry.
Ethylene Glycol n-Hexyl Ether found in the formulation of metalworking fluids, providing lubrication and cooling during machining processes.
Ethylene Glycol n-Hexyl Ether is used as an additive in concrete formulations to improve workability and setting time.

Safety profile:
According to the European Chemicals Agency, Ethylene Glycol n-Hexyl Ether is classified as harmful when in contact with skin and when swallowed.
Ethylene Glycol n-Hexyl Ether can also cause skin burns and serious eye damage.
Ethylene Glycol n-Hexyl Ether was also known to cause kidney injury and depression.

Ethylene Glycol n-Hexyl Ether is also a severe respiratory tract irritant.
Ethylene Glycol n-Hexyl Ether may also have blood effects.
Ethylene Glycol n-Hexyl Ether may enter the body through ingestion, aerosol inhalation, and through the skin.

Ethylene Glycol n-Hexyl Ether may form explosive peroxides.
Ethylene Glycol n-Hexyl Ether can react violently with strong oxidants.
Ethylene Glycol n-Hexyl Ether is classified as a green circle product EPA Safer Choice meaning it is of low concern.

Ethylene glycol n-hexyl ether may cause irritation to the skin and eyes upon contact.
Ethylene Glycol n-Hexyl Ether is important to use appropriate personal protective equipment, such as gloves and safety goggles, to prevent direct contact.
Inhalation of vapors or mists of ethylene glycol n-hexyl ether may cause respiratory irritation.

Adequate ventilation should be maintained in areas where it is used, and respiratory protection may be necessary.
Ingesting ethylene glycol n-hexyl ether can be harmful.

Ethylene Glycol n-Hexyl Ether is not intended for consumption, and ingestion may lead to adverse health effects.
While not highly flammable, ethylene glycol n-hexyl ether may pose a fire hazard under certain conditions.
Precautions should be taken to prevent ignition sources in areas where it is handled.

Synonyms:
2-(Hexyloxy)ethanol
112-25-4
Ethylene glycol monohexyl ether
2-Hexyloxyethanol
Ethanol, 2-(hexyloxy)-
2-HEXOXYETHANOL
Hexyl cellosolve
n-Hexyl cellosolve
Glycol monohexyl ether
Cellosolve, N-hexyl-
Ethylene glycol n-hexyl ether
2-Hexyloxy-1-ethanol
DTXSID1026908
7P0O8282NR
Ethylene glycol mono-n-hexyl ether
DTXCID606908
Ethanol, 2-hexyloxy-
2-(hexyloxy)ethan-1-ol
CAS-112-25-4
Ethylene glycol-n-monohexyl ether
HSDB 5569
2-n-(Hexyloxy)ethanol
EINECS 203-951-1
BRN 1734691
UNII-7P0O8282NR
2-hexyloxy-ethanol
MFCD00045997
2-(n-Hexyloxy)ethanol
Ethylenglykolmonohexylether
2-(1-Hexyloxy) ethanol
EC 203-951-1
SCHEMBL24741
31726-34-8
4-01-00-02383 (Beilstein Handbook Reference)
CHEMBL3188016
Tox21_202105
Tox21_300545
AKOS009156771
NCGC00248089-01
NCGC00248089-02
NCGC00254448-01
NCGC00259654-01
LS-13544
FT-0631642
H0343
EN300-114321
F71224
W-109065
Q27268660
Ethylene glycol monohexyl ether, BioXtra, >=99.0% (GC)
ETHYLENE UREA
CAS No.: 120-93-4
EC No.: 204-436-4
Molecular Weight: 86.09 g/mol
IUPAC Name: imidazolidin-2-one
Molecular Formula: C3H6N2O


DESCRIPTION:
2-Imidazolidone (Ethylene Urea) is a white crystalline powder, which can be dissolved in water.
Ethylene urea serves mainly as a formaldehyde scavenger and chemical building block.
Apart from the textile industry Ethylene urea is used in construction and coatings industry applications.
The Ethylene Urea 87% - also known as 2-Imidazolidinone hemihydrate – is mainly used in various kinds of formaldehyde removing formulations such as high-effect formaldehyde removing detergents and long-term formaldehyde dissolution intermediates.
In the flavor and fragrance industry the product is used as a release control agent.
The pharma industry is using the product as an intermediate for antibiotics such as Mezlocillin and Azlocillin.


Ethylene urea is an organic compound derived from formaldehyde and urea.
Ethylene urea is a colourless solid that is used for treating cellulose-based heavy fabrics to inhibit wrinkle formation.
Ethylene urea (DMEU) bonds with the hydroxyl groups present in long cellulose chains and prevents the formation hydrogen bonding between the chains, the primary cause of wrinkling.

This treatment produces permanently wrinkle-resistant fabrics and is different from the effects achieved from using fabric softeners.
An additional names for Ethylene urea includes 1,3-bis(hydroxymethyl)-tetrahydro-2-imidazolone


Main users are the leather, rubber, fragrance and textile coating industry.

APPLICATIONS OF ETHYLENE UREA:
• Textile auxiliaries
• Fragrance
• Pharma
Ethylene urea can be very affective at scavenging formaldehyde in various resin systems.
Reduction of 75% can be achieved depending on application conditions and the resin system properties.
The exact amount needed would depend on many variables, but laboratory experimentation should be performed to establish optimized dosage.
1. Textile industry
Cotton products are composed by long chain cellulose, which contains lots of hydroxyls to form spacious hydrogen bonds.
These hydrogen bonds will be broken and then randomly reformed under the heat or external forces. That’s how the fabric folds come.

2-Imidazolidone (Ethylene Urea) reacts with hydroxyl groups when treating fabrics together with formaldehyde, forming a stable structure to prevent the folds from forming.
This method can also restain the pungent odor caused from using formaldehyde only as the anti-wrinkle treatment by effectively inhibiting the release of formaldehyde.

Besides, urea resin is another widely used textile finishing agent.
Its residues on fabrics slowly release formaldehyde, which can be effectively inhibited by 2-Imidazolidone (Ethylene Urea).

Coating and Paint:
2-Imidazolidone (Ethylene Urea) can be used as de-aldehyde agent in poly-EVA, all kinds of water-based coatings, paints, pigments, adhesives and paper industry.
Ethylene Urea can also be added to the paint alone to make the paint absorbing and decomposing formaldehyde.

Ink for inkjet printers:
2-Imidazolidone (Ethylene Urea) is an important additives of ink for inkjets.
Ethylene Urea can disperse the pigment, lubricate the channels, prevent nozzles from drying out and blocking, and imporve the storage stability of ink.
Ethylene Urea can also imporve the color contrast to enhance the printing effect.

Adhesive:
Various types of artificial panels such as plywood, chipboard, fiberboard and composite panels, usually choose urea resin, phenolic resin or melamine resin as adhesives.
Those adhesives are produced from polycondensation between formaldehyde and urea, phenol or melamine respectively.
All of them have the problem of slowly releasing gaseous formaldehyde into the environment.
2-Imidazolidone (Ethylene Urea) can be added to effectively reduce the formaldehyde release and does not affect the bonding effect.

Daily Chemical:
2-Imidazolidone (Ethylene Urea) is the main composition of household de-aldehyde agent.
Ethylene Urea can be used as high-performance formaldehyde remover, home air formaldehyde potent enzyme, formaldehyde long-acting melting medium, aldehyde remover for glue, photocatalyst, floor deodorization care wax, furniture deodorizer, car deodorizer, etc.

Organic Synthesis:
2-Imidazolidone (Ethylene Urea) can be used as intermediates of many new antibiotics, such as meloxicillin and aloxicillin, as intermediates for anti-schistosomiasis drugs, and as basic raw materials of third-generation penicillin.
In the biological field, Ethylene Urea can be used to produce the plant growth regulators, fungicides, inhibitors, herbicides, etc., such as: N-chlorocarbonyl-2-imidazolidinone, 1-chlorocarbonyl-3-acetyl-2-imidazolidinone, 1-chlorocarbonyl-3-methanesulfonyl-2-imidazolidinone N-chloroformyl-2-imidazolidinone, 1-chloroformyl-3-acetyl-2-imidazolidinone, 1-chloroformyl-3-methanesulfonyl-2-imidazolidinone, N-hydroxyethyl-2-imidazolidinone, 1-methanesulfonyl-2-imidazolidinone, 1,3-dimethyl-2-imidazolidinone, 1-acetyl-2-imidazolidinone, etc




CAS No.: 120-93-4
EC No.: 204-436-4
Molecular Weight: 86.09 g/mol
IUPAC Name: imidazolidin-2-one
Molecular Formula: C3H6N2O




USES OF ETHYLENE UREA:
Ethylene urea is an organic intermediate used in various chemical industries.
Ethylene urea was originally used for the production of dimethylol ethylene urea thermosetting resins in textiles and paper.
Ethylene urea is also used as a scavenging agent to reduce the free formaldehyde in phenolic, melamine, glyoxal and urea formaldehyde resin systems for the coatings, construction and textile industries.

STORAGE CONDITIONS OF ETHYLENE UREA:
Ethylene urea has a shelf life of at least twelve months from the date of delivery; if stored in original unopened containers at temperatures not exceeding 30°C (86°F).
Continued storage beyond the designated shelf life does not necessarily mean the material cannot be used.
However, renewed testing of the most important properties is imperative.





CHEMICAL AND PHYSICAL PROPERTIES OF ETHYLENE UREA:
Molecular Weight: 86.09
XLogP3: -1.3
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 0
Exact Mass: 86.048012819
Monoisotopic Mass: 86.048012819
Topological Polar Surface Area: 41.1 Ų
Heavy Atom Count: 6
Formal Charge: 0
Complexity: 63.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Appearance: Clear Liquid
Color (APHA): <150
pH (neat): 6.0 to 7.0
Viscosity (cps): <100
Density (lbs / gal): 9.0 to 9.26


CAS No.: 120-93-4
EC No.: 204-436-4
Molecular Weight: 86.09 g/mol
IUPAC Name: imidazolidin-2-one
Molecular Formula: C3H6N2O

SAFETY INFORMATION ABOUT ETHYLENE UREA:

First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.





CAS No.: 120-93-4
EC No.: 204-436-4
Molecular Weight: 86.09 g/mol
IUPAC Name: imidazolidin-2-one
Molecular Formula: C3H6N2O






SYNONYMS OF ETHYLENE UREA:
MeSH Entry Terms:
2-imidazolidinone
ethylene urea
imidazolidin-2-one

Depositor-Supplied Synonyms:
2-Imidazolidone
imidazolidin-2-one
120-93-4
2-Imidazolidinone
ETHYLENEUREA
imidazolidinone
Ethylene urea
N,N'-Ethyleneurea
2-Oxoimidazolidine
1,3-Ethyleneurea
Imidazolid-2-one
Monoethyleneurea
2-Oxomidazolidine
Urea, 1,3-ethylene-
SD 6073
2-imidazolidinon
Urea, N,N'-(1,2-ethanediyl)-
NSC 21314
CHEBI:37001
Urea,3-ethylene-
NSC-21314
WLN: T5MVMTJ
2K48456N55
Urea,N'-(1,2-ethanediyl)-
HSDB 4021
EINECS 204-436-4
imidazolidone
2-imidazolinone
AI3-22151
imidazolin-2-one
UNII-2K48456N55
Imidazoliden-2-one
2-oxo-imidazolidine
MFCD00005257
2-Imidazolidone, 96%
DSSTox_CID_602
EC 204-436-4
ETHYLENEUREA [HSDB]
DSSTox_RID_75683
DSSTox_GSID_20602
CHEMBL12034
IMIDAZOLIDINONE [INCI]
2-IMIDAZOLIDINONE [MI]
DTXSID0020602
NSC3338
NSC-3338
NSC21314
ZINC1666720
Tox21_200783
AKOS000121325
7-Benzyloxy-1H-indole-3-carboxylicacid
NCGC00248832-01
NCGC00258337-01
AS-13128
BP-21148
CAS-120-93-4
DB-021217
DB-021218
AM20080146
CS-0075560
FT-0626340
FT-0668259
I0005
EN300-21266
D71145
2-Imidazolidinon 100 microg/mL in Acetonitrile
A804620
2-Imidazolidone, PESTANAL(R), analytical standard
Q-200290
Q2813813
F0001-0335
Z104494954
ETHYLENEDIAMINE
ETHYLENEDIAMINE = EDA

Ethylenediamine (abbreviated as en when a ligand) is the organic compound with the formula C2H4(NH2)2.
This colorless liquid with an ammonia-like odor is a basic amine.
Ethylenediamine is the first member of the so-called polyethylene amines.

CAS Number: 107-15-3
EC Number: 203-468-6
Chemical Formula: H2NCH2CH2NH2
Molar Mass: 60.10 g/mol

EDA is used as a building block for the synthesis of bleach activators, chelates and crop protection products.
Furthermore is used as an intermediate in applications like corrosion inhibitors, polyamide resins and lubricants/fuel additives.

Ethylenediamine is chain extender in the production of poyurethane resin for the water PU Dispersion (PUD).
Products derived from EDA are frequently used for bleach activators and chelates in detergents and for fungicides in crop protection area.

Polyamide resins find wide use as binders in printing inks for flexogravure application on certain paper, film, and foil webs and in hot-melt, pressure-sensitive, and heat-seal adhesives for leather, paper, plastic, and metal.
The main polyamide resin type, in addition to the liquid resins used as epoxy hardeners, is prepared generally by the condensation reaction of diamines with di- and polybasic fatty acids.

Thermoplastic polyamides are similarly used in formulating glossy, abrasion-resistant, overprint varnishes.
EDA is available as pure substance.

Ethylenediamine is a single-component product with two primary nitrogens.
Ethylenediamine has an ammonia-like odor and is clear and colorless.
Ethylenediamine is a widely used building block in chemical synthesis, with approximately 500,000 tonnes produced in 1998.

Ethylenediamine is an inflammable substance.
Ethylenediamine reacts severely to aldehyde and acids.

Ethylenediamine absorbs the carbon dioxide in the air.
Ethylenediamine is hygroscopic and resolves in water, ether, benzene, acetone and hexane.

Ethylenediamine (abbreviated as en when a ligand) is the organic compound with the formula C2H4(NH2)2.
This colorless liquid with an ammonia-like odor is a basic amine.

Ethylenediamine is a widely used building block in chemical synthesis, with approximately 500,000 tonnes produced in 1998.
Ethylenediamine is the first member of the so-called polyethylene amines.

Ethylenediamine (EDA) is the ethyleneamine with the lowest molecular weight.
Ethylenediamine contains two primary amine groups and is a colorless liquid.
Ethylenediamine is commonly used as an intermediate to produce detergents, chelates, textile auxiliaries, agrochemicals and polyamides.

Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products.
Ethylenediamine is also used as an excipient in many pharmacological preparations such as creams.

Notably, ethylenediamine is a contact sensitizer capable of producing local and generalized reactions.
Sensitivity to ethylenediamine may be identified with a clinical patch test.

Ethylenediamine is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 tonnes per annum.
Ethylenediamine is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Ethylenediamine appears as a clear colorless liquid with an ammonia-like odor.
Ethylenediamine is flash point of 91 °F and a melting point of 47 °F.

Ethylenediamine is corrosive to tissue.
Ethylenediamine is vapors are heavier than air.

Ethylenediamine is produces toxic oxides of nitrogen during combustion.
Ethylenediamine is density 7.5 lb / gal.
Ethylenediamine is used to make other chemicals and as a fungicide.

Ethylenediamine is an alkane-alpha,omega-diamine in which the alkane is ethane.
Ethylenediamine has a role as a GABA agonist.
Ethylenediamine derives from a hydride of an ethane.

Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products.
Ethylenediamine is also used as an excipient in many pharmacological preparations such as creams.

Notably, ethylenediamine is a contact sensitizer capable of producing local and generalized reactions.
Sensitivity to ethylenediamine may be identified with a clinical patch test.

Usage Area of Ethylenediamine:
Ethylenediamine is used in the textile sector.
Ethylenediamine is used the fields of fiber, polyamide and rubber.

Ethylenediamine is used as a chelator and a corrosion inhibitor.
Ethylenediamine is used as a lubricant in the plastics sector.
Ethylenediamine is used in foam making operations.

Uses of Ethylenediamine:
Ethylenediamine is used in the manufacture of chelating agents, fungicides, waxes, polyamide resins, and corrosion inhibitors.
Ethylenediamine is used as an emulsifier, an inhibitor in antifreeze solutions, and an additive to pharmaceuticals and textile lubricants.

Ethylenediamine is used in photography (color developing baths).
Ethylenediamine is used in prepn of dyes, synthetic waxes, resins, insecticides and asphalt wetting agents.

Drug Indication:
Ethylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.

Widespread uses by professional workers:
Ethylenediamine is used in the following products: adhesives and sealants, coating products, pH regulators and water treatment products, fillers, putties, plasters, modelling clay and water treatment chemicals.
Ethylenediamine is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment, health services and scientific research and development.
Other release to the environment of Ethylenediamine is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

Uses at industrial sites:
Ethylenediamine is used in the following products: pH regulators and water treatment products, adhesives and sealants, coating products, heat transfer fluids, hydraulic fluids and polymers.
Ethylenediamine has an industrial use resulting in manufacture of another substance (use of intermediates).

Ethylenediamine is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Ethylenediamine is used for the manufacture of: chemicals.
Release to the environment of Ethylenediamine can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture, in processing aids at industrial sites, of substances in closed systems with minimal release, in the production of articles and as processing aid.

Industry Uses:
Hardener
Intermediate
Intermediates
Processing aids, specific to petroleum production
Soil amendments (fertilizers)

Industrial Processes with risk of exposure:
Textiles (Fiber & Fabric Manufacturing)
Painting (Pigments, Binders, and Biocides)
Photographic Processing

Other Uses of Ethylenediamine:
Corrosion inhibitors
Wet-strength resins
Fabric softeners
Epoxy curing agents
Polyamide resins
Fuel additives
Lube oil additives
Asphalt additives
Ore flotation
Corrosion inhibitors
Ore flotation
Asphalt
Additives
Corrosion inhibitors
Epoxy curing agents
Hydrocarbon purification
Lube oil & fuel additives
Mineral processing aids
Polyamide resins
Surfactants
Textile additives-paper wet-strength resins
Fabric softeners
Surfactants
Coatings
Urethanes
Fuel additives
Chemical intermediates
Epoxy curing agents
Lube oils
Wet strength resins

Applications of Ethylenediamine:
Ethylenediamine is used in large quantities for production of many industrial chemicals.
Ethylenediamine forms derivatives with carboxylic acids (including fatty acids), nitriles, alcohols (at elevated temperatures), alkylating agents, carbon disulfide, and aldehydes and ketones.
Because of Ethylenediamine bifunctional nature, having two amines, Ethylenediamine readily forms heterocycles such as imidazolidines.

Precursor to chelation agents, drugs, and agrochemicals:
A most prominent derivative of ethylenediamine is the chelating agent EDTA, which is derived from ethylenediamine via a Strecker synthesis involving cyanide and formaldehyde.
Hydroxyethylethylenediamine is another commercially significant chelating agent.

Numerous bio-active compounds and drugs contain the N-CH2-CH2-N linkage, including some antihistamines.
Salts of ethylenebisdithiocarbamate are commercially significant fungicides under the brand names Maneb, Mancozeb, Zineb, and Metiram.
Some imidazoline-containing fungicides are derived from ethylenediamine.

Pharmaceutical Ingredient:
Ethylenediamine is an ingredient in the common bronchodilator drug aminophylline, where Ethylenediamine serves to solubilize the active ingredient theophylline.
Ethylenediamine has also been used in dermatologic preparations, but has been removed from some because of causing contact dermatitis.

When used as a pharmaceutical excipient, after oral administration Ethylenediamine bioavailability is about 0.34, due to a substantial first-pass effect.
Less than 20% is eliminated by renal excretion.

Ethylenediamine-derived antihistamines are the oldest of the five classes of first-generation antihistamines, beginning with piperoxan aka benodain, discovered in 1933 at the Pasteur Institute in France, and also including mepyramine, tripelennamine, and antazoline.
The other classes are derivatives of ethanolamine, alkylamine, piperazine, and others (primarily tricyclic and tetracyclic compounds related to phenothiazines, tricyclic antidepressants, as well as the cyproheptadine-phenindamine family)

Role in Polymers:
Ethylenediamine, because Ethylenediamine contains two amine groups, is a widely used precursor to various polymers.
Condensates derived from formaldehyde are plasticizers.

Ethylenediamine is widely used in the production of polyurethane fibers.
The PAMAM class of dendrimers are derived from ethylenediamine.

Tetraacetylethylenediamine:
The bleaching activator tetraacetylethylenediamine is generated from ethylenediamine.
The derivative N,N-ethylenebis(stearamide) (EBS) is a commercially significant mold-release agent and a surfactant in gasoline and motor oil.

Other Applications:
As a solvent, Ethylenediamine is miscible with polar solvents and is used to solubilize proteins such as albumins and casein.
Ethylenediamine is also used in certain electroplating baths.

As a corrosion inhibitor in paints and coolants.
Ethylenediamine dihydroiodide (EDDI) is added to animal feeds as a source of iodide.

Chemicals for color photography developing, binders, adhesives, fabric softeners, curing agents for epoxies, and dyes.
As a compound to sensitize nitromethane into an explosive.
This mixture was used at Picatinny Arsenal during WWII, giving the nitromethane and ethylenediamine mixture the nickname PLX, or Picatinny Liquid Explosive.

Benefits of Ethylenediamine:
Consistent and predictable reaction products
Easily derivatized
Low vapor pressure
High viscosity
Low environmental impact
Suitable for harsh conditions
Low sensitivity
Versatile

Functions of Ethylenediamine:
Raw Material,
Scale inhibitor,
Chemical Intermediate,
Chemical Reagent,
Dispersing Agent,
Scale Removal and Control

Human Metabolite Information of Ethylenediamine:

Tissue Locations:
Kidney
Liver

Cellular Locations:
Cytoplasm
Extracellular

Synthesis of Ethylenediamine:
Ethylenediamine is produced industrially by treating 1,2-dichloroethane with ammonia under pressure at 180 °C in an aqueous medium.

In this reaction hydrogen chloride is generated, which forms a salt with the amine.
The amine is liberated by addition of sodium hydroxide and can then be recovered by rectification.
Diethylenetriamine (DETA) and triethylenetetramine (TETA) are formed as by-products.

Another industrial route to ethylenediamine involves the reaction of ethanolamine and ammonia.

This process involves passing the gaseous reactants over a bed of nickel heterogeneous catalysts.

Ethylenediamine can be produced in the lab by the reaction of ethylene glycol and urea.
Ethylenediamine can be purified by treatment with sodium hydroxide to remove water followed by distillation.

General Manufacturing Information of Ethylenediamine:

Industry Processing Sectors:
Agriculture, Forestry, Fishing and Hunting
All Other Basic Inorganic Chemical Manufacturing
All Other Basic Organic Chemical Manufacturing
All Other Chemical Product and Preparation Manufacturing
Not Known or Reasonably Ascertainable
Oil and Gas Drilling, Extraction, and Support activities
Paint and Coating Manufacturing
Petrochemical Manufacturing
Petroleum Refineries
Pharmaceutical and Medicine Manufacturing
Wholesale and Retail Trade

Coordination Chemistry of Ethylenediamine:
Ethylenediamine is a well-known bidentate chelating ligand for coordination compounds, with the two nitrogen atoms donating their lone pairs of electrons when ethylenediamine acts as a ligand.
Ethylenediamine is often abbreviated "en" in inorganic chemistry.

The complex [Co(ethylenediamine)3]3+ is an archetypical chiral tris-chelate complex.
The salen ligands, some of which are used in catalysis, are derived from the condensation of salicylaldehydes and ethylenediamine.

Related ligands:
Related derivatives of ethylenediamine include ethylenediaminetetraacetic acid (EDTA), tetramethylethylenediamine (TMEDA), and tetraethylethylenediamine (TEEDA).
Chiral analogs of ethylenediamine include 1,2-diaminopropane and trans-diaminocyclohexane.

Handling and Storage of Ethylenediamine:

Nonfire Spill Response:
ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.
All equipment used when handling the product must be grounded.

Do not touch or walk through spilled material.
Stop leak if you can do Ethylenediamine without risk.

Prevent entry into waterways, sewers, basements or confined areas.
A vapor-suppressing foam may be used to reduce vapors.

Absorb with earth, sand or other non-combustible material.
For hydrazine, absorb with DRY sand or inert absorbent (vermiculite or absorbent pads).
Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL:
Dike far ahead of liquid spill for later disposal.
Water spray may reduce vapor, but may not prevent ignition in closed spaces.

Safe Storage:
Separated from strong oxidants, acids, chlorinated organic compounds and food and feedstuffs.
Store only in original container.

Storage Conditions:
Outside or detached storage is preferred.
Avoid oxidizing materials, acids, and sources of halogens.
Store in a cool, dry, well-ventilated location.

Safety of Ethylenediamine:
Ethylenediamine, like ammonia and other low-molecular weight amines, is a skin and respiratory irritant.
Unless tightly contained, liquid ethylenediamine will release toxic and irritating vapors into Ethylenediamine surroundings, especially on heating.
The vapors absorb moisture from humid air to form a characteristic white mist, which is extremely irritating to skin, eyes, lungs and mucus membranes.

First Aid Measures of Ethylenediamine:
Exposure to ethylenediamine may result in cough, difficulty in breathing, irritation of the lungs, and pneumonia.
Nausea, vomiting, and diarrhea are often seen.
Contact with ethylenediamine may result in redness, pain, irritation, and burns.

Emergency Life-Support Procedures:
Exposure to ethylenediamine may require decontamination and life support for the victims.
Emergency personnel should wear protective clothing appropriate to the type and degree of contamination.

Air-purifying or supplied-air respiratory equipment should also be worn, as necessary.
Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air.
Emergency personnel should avoid self-exposure to ethylenediamine.

2. Evaluate vital signs including pulse and respiratory rate, and note any trauma.
If no pulse is detected, provide CPR.

If not breathing, provide artificial respiration.
If breathing is labored, administer oxygen or other respiratory support.

3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

4. Transport to a health care facility.

Dermal/Eye Exposure:

1. Remove victims from exposure.
Emergency personnel should avoid self- exposure to ethylenediamine.

2. Evaluate vital signs including pulse and respiratory rate, and note any trauma.
If no pulse is detected, provide CPR.

If not breathing, provide artificial respiration.
If breathing is labored, administer oxygen or other respiratory support.

3. Remove contaminated clothing as soon as possible.

4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.

5. Thoroughly wash exposed skin areas with water for at least 15 minutes.

6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

7. Transport to a health care facility.

Ingestion Exposure:

1. Evaluate vital signs including pulse and respiratory rate, and note any trauma.
If no pulse is detected, provide CPR.

If not breathing, provide artificial respiration.
If breathing is labored, administer oxygen or other respiratory support.

2. DO NOT induce vomiting.

3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

4. Activated charcoal is of no value.

5. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults, 250 mL (8 oz or 1 cup).
Water or milk should be given only if victims are conscious and alert.

6. Transport to a health care facility.

Fire Fighting of Ethylenediamine:
Wear full protective clothing including gloves and boots.
If necessary to enter closed area, wear full-faced gas masks with self-contained breathing apparatus.

Use water spray, dry chemical, alcohol foam, or carbon dioxide.
Do not use water in case of drum or tank fires.

If a leak or spill has not ignited, use water spray to reduce the vapors and dilute spills to nonflammable mixtures.
Use water to keep fire-exposed containers cool.

Fire Fighting Procedures:
Use water spray, dry chem, "alcohol resistant" foam, or carbon dioxide. Use water spray to keep fire-exposed containers cool.
Solid streams may be ineffective and spread material.

Identifiers of Ethylenediamine:
CAS Number: 107-15-3
Abbreviations: en
Beilstein Reference: 605263
ChEBI: CHEBI:30347
ChEMBL: ChEMBL816
ChemSpider: 13835550
ECHA InfoCard: 100.003.154
EC Number: 203-468-6
Gmelin Reference: 1098
KEGG: D01114
MeSH: ethylenediamine
PubChem CID: 3301
RTECS number: KH8575000
UNII: 60V9STC53F
UN number: 1604
CompTox Dashboard (EPA): DTXSID5021881
InChIInChI=1S/C2H8N2/c3-1-2-4/h1-4H2
Key: PIICEJLVQHRZGT-UHFFFAOYSA-N
SMILES: NCCN

Synonyms: 1,2-Diaminoethane
Linear Formula: NH2CH2CH2NH2
CAS Number: 107-15-3
Molecular Weight: 60.10
EC Number: 203-468-6

CAS number: 107-15-3
EC index number: 612-006-00-6
EC number: 203-468-6
Hill Formula: C₂H₈N₂
Chemical formula: H₂NCH₂CH₂NH₂
Molar Mass: 60.10 g/mol
HS Code: 2921 21 00

Properties of Ethylenediamine:
Chemical formula: C2H8N2
Molar mass: 60.100 g·mol−1
Appearance: Colorless liquid[3]
Odor: Ammoniacal[3]
Density: 0.90 g/cm3[3]
Melting point: 8 °C (46 °F; 281 K)[3]
Boiling point: 116 °C (241 °F; 389 K)[3]
Solubility in water: miscible
log P: −2.057
Vapor pressure: 1.3 kPa (at 20 °C)
Henry's law constant (kH): 5.8 mol Pa−1 kg−1
Magnetic susceptibility (χ):
-46.26·10−6 cm3/mol
-76.2·10−6 cm3/mol (HCl salt)
Refractive index (nD): 1.4565

Density: 0.897 g/cm3 (20 °C)
Explosion limit: 2 - 17 %(V)
Flash point: 38 °C
Ignition temperature: 405 °C
Melting Point: 11.1 °C
pH value: 12.2 (100 g/l, H₂O, 20 °C)
Vapor pressure: 12 hPa (20 °C)

Formula: C2H8N2
Formula mass: 60.10
Melting point, °C: 8.5
Boiling point, °C: 117
Vapor pressure, mmHg: 16 (25 C)
Vapor density (air=1): 2.07
Saturation Concentration: 1.3% at 20 C
Evaporization number: 0.91 (butyl acetate = 1)
Critical temperature: 340
Critical pressure: 66.19
Density: 0.898 g/cm3 (20 C)
Solubility in water: Miscible
Viscosity: 1.54 cp (25 C)
Surface tension: 40.77 g/s2 (20 C)
Refractive index: 1.454 (20 C)
Dipole moment: 1.83 D (25 C)
Dielectric constant: 16 (18 C)
pKa/pKb: 4.11 (pKb)
Partition coefficient, pKow: -2.04
Heat of fusion: 19.3 kJ/mol
Heat of vaporization: 46.9 kJ/mol
Heat of combustion: -1890 kJ/mol

Molecular Weight: 60.10
XLogP3: -2
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 1
Exact Mass: 60.068748264
Monoisotopic Mass: 60.068748264
Topological Polar Surface Area: 52 Ų
Heavy Atom Count: 4
Complexity: 6
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Ethylenediamine:
Color according to color reference solution Ph.Eur.: colorless liquid
Assay (GC, area%): ≥ 99.0 % (a/a)
Water (GC, area%): ≤ 1.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.896 - 0.898
Identity (IR): passes test

Melting Point: >300.0°C
Color: White
pH: 3.9 to 5 (1% aq. soln.)
Assay Percent Range: 98+%
Infrared Spectrum: Authentic
Linear Formula: H2NCH2CH2NH2·2HCl
Beilstein: 04, 230
Packaging: Plastic bottle
Merck Index: 15, 3849
Quantity: 100 g
Solubility Information: (1% in water) Clear colorless
IUPAC Name: ethane-1,2-diamine;dihydrochloride
Formula Weight: 133.04
Percent Purity: 98+%
Physical Form: Crystalline Powder
Chemical Name or Material: Ethylenediamine dihydrochloride, 98+%

Thermochemistry of Ethylenediamine:
Heat capacity (C): 172.59 J K−1 mol−1
Std molar entropy (S⦵298): 202.42 J K−1 mol−1
Std enthalpy of formation (ΔfH⦵298): −63.55–−62.47 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): −1.8678–−1.8668 MJ mol−1

Related compounds of Ethylenediamine:
Ethylamine
Ethylenedinitramine

Related alkanamines:
1,2-Diaminopropane
1,3-Diaminopropane

Names of Ethylenediamine:

Regulatory process names:
1,2-Diamino-ethaan
1,2-Diamino-ethano
1,2-Diaminoaethan
1,2-Diaminoethane
1,2-diaminoethane
1,2-Ethanediamine
1,2-Ethylenediamine
Aethaldiamin
Aethylenediamin
Algicode 106L
Amerstat 274
beta-Aminoethylamine
Dimethylenediamine
Edamine
Ethyleendiamine
Ethylendiamine
Ethylenediamine
ETHYLENEDIAMINE
ethylenediamine
Ethylenediamine
EDA
ethylenediamine; 1,2-diaminoethane

Translated names:
1,2 diaminoetaani (fi)
1,2-Diamino-ethan (de)
1,2-diaminoetaan (et)
1,2-diaminoetan (hr)
1,2-diaminoetan (no)
1,2-diaminoetan (pl)
1,2-diaminoetan (ro)
1,2-diaminoetan (sl)
1,2-diaminoetan (sv)
1,2-diaminoetanas (lt)
1,2-diaminoetán (hu)
1,2-diaminoetāns (lv)
1,2-диаминоетан (bg)
etano-1,2-diamina (pl)
ethan-1,2-diamin (cs)
ethyleendiamine (nl)
ethylendiamin (cs)
ethylendiamin (da)
Ethylendiamin (de)
etilen-diamina (ro)
etilendiamin (hr)
etilendiamin (sl)
etilendiamina (es)
etilendiamina (it)
etilendiaminas (lt)
etilenodiamina (pt)
etilén-diamin (hu)
etilēndiamīns (lv)
etyleenidiamiini (fi)
etylendiamin (no)
etylendiamin (sv)
etylenodiamina (pl)
etyléndiamín (sk)
etán-1,2-diamín (sk)
Etüleendiamiin (et)
éthylènediamine;1,2-diaminoéthane (fr)
αιθυλενοδιαμίν (el)
етилендиамин (bg)

CAS name:
1,2-Ethanediamine

IUPAC names:
1,2,-Diaminoethane
1,2-Diaminoethane
1,2-diaminoethane
1,2-Diaminoethane , 1,2-Ethylenediamine , 1,4-Diazabutane , Dimethylenediamine
1,2-Ethanediamine
Diaminoethane
Ethane-1,2-diamine
ethane-1,2-diamine
ethane-1,2-diamine
Ethylendiamin
ethylene diamine
Ethylene diamine
ethylene diamine
Ethylenediamine
ethylenediamine
Ethylenediamine
ethylenediamine 1,2-diaminoethane
Ethylenediamine Anhydrous
ethylenediamine; 1,2-diaminoethane

Preferred IUPAC name:
Ethane-1,2-diamine

Trade names:
Bruggolen P22
EDA
Ethylenediamine
ETHYLENEDIAMINE (EDA)
ETHYLENEDIAMINE.
Ethylenediamine.

Other names:
Edamine,
1,2-Diaminoethane,
'en' when a ligand

Synonyms of Ethylenediamine:
ethylenediamine
Ethane-1,2-diamine
107-15-3
1,2-Ethanediamine
1,2-Diaminoethane
Ethylene diamine
Ethylendiamine
edamine
Dimethylenediamine
1,2-Ethylenediamine
Aethaldiamin
Aethylenediamin
Ethyleendiamine
Ethylene-diamine
beta-Aminoethylamine
1,2-Diaminoaethan
Algicode 106L
Amerstat 274
1,2-Diamino-ethaan
1,2-Diamino-ethano
Ethylenediamine [JAN]
NCI-C60402
Edamine [INN]
ETHYLENEDIAMINE ANHYDROUS
CHEBI:30347
CHEMBL816
H2NCH2CH2NH2
ETHANE,1,2-DIAMINO
60V9STC53F
27308-78-7
2-Aminoethylammonium chloride
1, 2-Diaminoethane
NCGC00091527-01
1,2-diaminoethane phase II
EN
1,2-diaminoethane phase I beta
Aethaldiamin [German]
Caswell No. 437
1,2-diaminoethane phase I alpha
Ethyleendiamine [Dutch]
Aethylenediamin [German]
Ethylene-diamine [French]
Ethane-1,2-diammonium bromide
CAS-107-15-3
Ethylenediamine, ReagentPlus(R), >=99%
1,2-Diaminoaethan [German]
1,2-Diamino-ethaan [Dutch]
CCRIS 5224
HSDB 535
1,2-Diamino-ethano [Italian]
Aminophylline Injection
EINECS 203-468-6
UN1604
EPA Pesticide Chemical Code 004205
Ethylenediamine [USP:JAN]
BRN 0605263
UNII-60V9STC53F
ethylenediarnine
AI3-24231
2-aminoethylamine
ethylene di amine
1,4-diazabutane
1,2-diaminoethan
ethylene - diamine
EDN
1,2-ethylendiamine
MFCD00008204
1,2-diamino-ethane
ethane 1,2-diamine
N,N'-ethylenediamine
Ethylenediamine, 8CI
1,2-ethylene diamine
1,2-ethylene-diamine
Ethylenediamine [UN1604] [Corrosive]
.beta.-Aminoethylamine
ethane-1, 2-diamine
N,N'-ethylene diamine
Ethylenediamine, BioXtra
Epitope ID:117724
EC 203-468-6
ETHYLENEDIAMINE [II]
ETHYLENEDIAMINE [MI]
4-04-00-01166 (Beilstein Handbook Reference)
Ethylenediamine (USP/JP15)
Ethylenediamine (USP/JP17)
ETHYLENEDIAMINE [HSDB]
ETHYLENEDIAMINE [INCI]
BDBM7972
NH2(CH2)2NH2
ETHYLENEDIAMINE [MART.]
DTXSID5021881
ETHYLENEDIAMINE [WHO-DD]
624-59-9 (di-hydrobromide)
333-18-6 (di-hydrochloride)
5700-49-2 (di-hydriodide)
Ethylenediamine, analytical standard
STR00309
Tox21_111145
Tox21_201202
STL264241
ZINC37253587
ETHYLENEDIAMINE [EP MONOGRAPH]
AKOS000118850
DB14189
ETHYLENEDIAMINE [USP MONOGRAPH]
UN 1604
Ethylenediamine, for synthesis, 99.0%
NCGC00091527-02
NCGC00258754-01
BP-20367
Ethylenediamine [UN1604] [Corrosive]
E0077
E0081
EN300-19398
D01114
Ethylenediamine, SAJ special grade, >=99.0%
Ethylenediamine, meets USP testing specifications
Ethylenediamine, Vetec(TM) reagent grade, >=98%
Q411362
J-001723
Ethylenediamine, purified by redistillation, >=99.5%
TIZANIDINE HYDROCHLORIDE IMPURITY H [EP IMPURITY]
Z104473714
Ethylenediamine, puriss. p.a., absolute, >=99.5% (GC)
QuadraPure(R) AEA, 100-400 mum particle size, extent of labeling: 1.3 mmol/g loading, 1 % cross-linked with divinylbenzene
Ethylenediamine [JAN] [Wiki]
1,2-diamino ethane
1,2-DIAMINOETHANE
1,2-Ethandiamin [German] [ACD/IUPAC Name]
1,2-Ethanediamine [ACD/Index Name] [ACD/IUPAC Name]
1,2-Éthanediamine [French] [ACD/IUPAC Name]
1,2-ethylenediamine
107-15-3 [RN]
203-468-6 [EINECS]
605263 [Beilstein]
edamina [Spanish] [INN]
edamine [INN]
édamine [French] [INN]
edaminum (R) [Latin] [INN]
ethane-1,2-diamine
ethylene diamine
MFCD00008204 [MDL number]
эдамин [Russian] [INN]
乙二胺 [Chinese] [INN]
1,2-Diamino-ethaan [Dutch]
1,2-Diaminoethane, 1,2-Ethanediamine
1,2-Diamino-ethano [Italian]
1,4-DIAZABUTANE
2-aminoethynylamine
4-04-00-01166 [Beilstein]
8030-24-8 secondary RN [RN]
Aethaldiamin [German]
Aethylenediamin [German]
Amerstat 274
Diaminoethane
Dimethylenediamine
EDA (ethylenediamine)
EDN
EPI-DA (ethylenediamine)
ETHANE,1,2-DIAMINO
Ethyleendiamine [Dutch]
Ethylendiamine
Ethylene-d4 Diamine
Ethylene-diamine [French]
Ethylenediaminemissing
ethyne-1,2-diamine
β-Aminoethylamine
β-Aminoethylamine
ETHYLENEDIAMINE
Ethylenediamine appears as a clear colorless liquid with an ammonia-like odor.
Ethylenediamine is an alkane-alpha,omega-diamine in which the alkane is ethane.
Ethylenediamine derives from a hydride of an ethane.


CAS Number: 107-15-3
EC Number: 203-468-6
Molecular Formula: C2H8N2 or H2NCH2CH2NH2 or NH2CH2CH2NH2


Ethylenediamine's Flash point is 91 °F and a melting point of 47 °F.
Ethylenediamine's Vapors are heavier than air.
Ethylenediamine's density is 7.5 lb / gal.


Ethylenediamine is an alkane-alpha,omega-diamine in which the alkane is ethane.
Ethylenediamine has a role as a GABA agonist.
Ethylenediamine derives from a hydride of an ethane.


Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products.
Sensitivity to ethylenediamine may be identified with a clinical patch test.
Ethylenediamine (abbreviated as en when a ligand) is the organic compound with the formula C2H4(NH2)2.


This colorless liquid, Ethylenediamine, with an ammonia-like odor is a basic amine.
Ethylenediamine is a widely used building block in chemical synthesis, with approximately 500,000 tonnes produced in 1998.
Ethylenediamine is the first member of the so-called polyethylene amines.


Ethylenediamine dihydrochloride is a glycol ether that has been used as a solvent and plasticizer.
Ethylenediamine has the ability to convert nitrite ions into nitrous acid, which is an important reaction in the formation of DNA.
Ethylenediamine has been studied for its potential use in transfection experiments and structural analysis.


Ethylenediamine is also an ingredient of aminophylline, a xanthine bronchodilator used in the treatment of asthma and other respiratory problems.
Other medications where Ethylenediamine or its derivatives are found include some antihistamines and anti-nausea agents.
Ethylenediamine is thick, colorless to light-yellowish liquid with an ammonia-like odor, hygroscopic, lachrymator.


Ethylenediamine is the organic compound with the formula C2H4(NH2)2.
This colorless liquid, Ethylenediamine, with an ammonia-like odor is a strongly basic amine.
Ethylenediamine is a widely used building block in chemical synthesis, with approximately 500,000,000 kg being produced in 1998.


Ethylenediamine is the ethyleneamine with the lowest molecular weight.
Ethylenediamine contains two primary amine groups and is a colorless liquid.
Ethylenediamine is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 tonnes per annum.



USES and APPLICATIONS of ETHYLENEDIAMINE:
Ethylenediamine is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Release to the environment of Ethylenediamine can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release.


Ethylenediamine can be found in products with material based on: wood (e.g. floors, furniture, toys).
Ethylenediamine is used in the following products: adhesives and sealants, coating products, pH regulators and water treatment products, fillers, putties, plasters, modelling clay and water treatment chemicals.


Ethylenediamine is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment, health services and scientific research and development.
Ethylenediamine is used in the following products: fuels.


Other release to the environment of Ethylenediamine is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Ethylenediamine has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of Ethylenediamine can occur from industrial use: formulation of mixtures.
Ethylenediamine is used in the following products: pH regulators and water treatment products, adhesives and sealants, coating products, heat transfer fluids, hydraulic fluids and polymers.


Ethylenediamine has an industrial use resulting in manufacture of another substance (use of intermediates).
Ethylenediamine is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Ethylenediamine is used for the manufacture of: chemicals.


Release to the environment of Ethylenediamine can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture, in processing aids at industrial sites, of substances in closed systems with minimal release, in the production of articles and as processing aid.


Release to the environment of Ethylenediamine can occur from industrial use: manufacturing of the substance.
Ethylenediamine is used in large quantities for production of many industrial chemicals.
Ethylenediamine forms derivatives with carboxylic acids (including fatty acids), nitriles, alcohols (at elevated temperatures), alkylating agents, carbon disulfide, and aldehydes and ketones.


Because of its bifunctional nature, having two amines, Ethylenediamine readily forms heterocycles such as imidazolidines.
Ethylenediamine is used to make other chemicals and as a fungicide.
Ethylenediamine is also used as an excipient in many pharmacological preparations such as creams.


Notably, ethylenediamine is a contact sensitizer capable of producing local and generalized reactions.
Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products.
Ethylenediamine is also used as an excipient in many pharmacological preparations such as creams.


Notably, Ethylenediamine is a contact sensitizer capable of producing local and generalized reactions.
Sensitivity to Ethylenediamine may be identified with a clinical patch test.
Ethylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.


Ethylenediamine is used mainly as a building block for crop protection products, in the synthesis of chelating agents and for low-temperature-active bleaching agents.
The many other applications of Ethylenediamine include polyamides, lubricants, fuel additives and textiles.
Ethylenediamine is used as a building block for the synthesis of bleach activators, chelates and crop protection products.


Furthermore Ethylenediamine is used as an intermediate in applications like corrosion inhibitors, polyamide resins and lubricants/fuel additives.
Chain extender in the production of poyurethane resin for the water PU Dispersion (PUD).
Products derived from Ethylenediamine are frequently used for bleach activators and chelates in detergents and for fungicides in crop protection area.


Ethylenediamine is used as a solvent, it is miscible with polar solvents and is used to solubilize proteins such as albumins and casein.
Ethylenediamine is also used in certain electroplating baths.
Ethylenediamine is used as a corrosion inhibitor in paints and coolants.


Ethylenediamine is added to animal feeds as a source of iodide.
Ethylenediamine is used as chemicals for color photography developing, binders, adhesives, fabric softeners, curing agents for epoxies, and dyes.
Ethylenediamine is used as a compound to sensitize nitromethane into an explosive.


This mixture was used at Picatinny Arsenal during WWII, giving the nitromethane and ethylenediamine mixture the nickname PLX, or Picatinny Liquid Explosive.
Ethylenediamine is commonly used as an intermediate to produce detergents, chelates, textile auxiliaries, agrochemicals and polyamides.
Uses of Ethylenediamine: Solvent for casein, albumin, shellac, and sulfur, emulsifier, stabilizing rubber latex, as inhibitor in antifreeze solutions, in textile lubricants, pharmaceutic aid (aminophylline injection stabilizer).


Ethylenediamine dihydrochloride can also be used to study phase transitions at different temperatures, as well as its electrochemical properties.
Ethylenediamine is used as a solvent, it is miscible with polar solvents and is used to solubilize proteins such as albumins and casein.
Ethylenediamine is also used in certain electroplating baths.


Ethylenediamine is used as a corrosion inhibitor in paints and coolants.
Ethylenediamine is added to animal feeds as a source of iodide.
Ethylenediamine is used as chemical for color photography developing, binders, adhesives, fabric softeners, curing agents for epoxys, and dyes.


Ethylenediamine is used in large quantities for production of many industrial chemicals.
Ethylenediamine forms derivatives with carboxylic acids (including fatty acids), nitriles, alcohols (at elevated temperatures), alkylating agents, carbon disulfide, and aldehydes and ketones.
Because of its bifunctional nature, having two amines, Ethylenediamine readily forms heterocycles such as imidazolidines.


-Pharmaceutical ingredient:
Ethylenediamine is an ingredient in the common bronchodilator drug aminophylline, where it serves to solubilize the active ingredient theophylline.
Ethylenediamine has also been used in dermatologic preparations, but has been removed from some because of causing contact dermatitis.
When used as a pharmaceutical excipient, after oral administration Ethylenediamine's bioavailability is about 0.34, due to a substantial first-pass effect.
Less than 20% is eliminated by renal excretion.
Ethylenediamine-derived antihistamines are the oldest of the five classes of first-generation antihistamines, beginning with piperoxan aka benodain, discovered in 1933 at the Pasteur Institute in France, and also including mepyramine, tripelennamine, and antazoline.
The other classes are derivatives of ethanolamine, alkylamine, piperazine, and others (primarily tricyclic and tetracyclic compounds related to phenothiazines, tricyclic antidepressants, as well as the cyproheptadine-phenindamine family)


-Role in polymers:
Ethylenediamine, because it contains two amine groups, is a widely used precursor to various polymers.
Condensates derived from formaldehyde are plasticizers.
Ethylenediamine is widely used in the production of polyurethane fibers.
The PAMAM class of dendrimers are derived from ethylenediamine.


-Uses of Ethylenediamine:
*Corrosion inhibitors
*Wet-strength resins
*Fabric softeners
*Epoxy curing agents
*Polyamide resins
*Fuel additives
*Lube oil additives
*Asphalt additives


-Uses of Ethylenediamine:
*Ore flotation
*Corrosion inhibitors
*Ore flotation
*Asphalt
*Additives
*Corrosion inhibitors
*Epoxy curing agents
*Hydrocarbon purification
*Lube oil & fuel additives
*Mineral processing aids
*Polyamide resins


-Uses of Ethylenediamine:
*Surfactants
*Textile additives-paper wet-strength resins
*Fabric softeners
*Surfactants
*Coatings
*Urethanes
*Fuel additives
*Chemical intermediates
*Epoxy curing agents
*Lube oils
*Wet strength resins


-Uses of Ethylenediamine:
*Bleach Activator
*Chelating Agents
*Epoxy Curing Agents
*Fungicides
*Industrial Surfactants
*Lube, Oil and Fuel Additives
*Phosphonates
*Plastic Lubricants
*Polyamide Resins
*Urethane Chemicals
*Other applications



BENEFITS OF ETHYLENEDIAMINE:
*Consistent and predictable reaction products
*Easily derivatized
*Low vapor pressure
*High viscosity
*Low environmental impact
*Suitable for harsh conditions
*Low sensitivity
*Versatile



MARKETS OF ETHYLENEDIAMINE:
*Aerospace, Marine and Automotive
*Agriculture
*Construction and Housing
*Consumer Electronics
*Household Detergents and Cleaners
*Human and Animal Health Care
*Food
*Industrial Cleaners and Preservants
*Mining
*Personal Care
*Pulp and Paper
*Road Construction
*Textiles and Sports



BENEFITS OF ETHYLENEDIAMINE:
*Consistent and predictable reaction products
*Easily derivatized
*Low vapor pressure
*High viscosity
*Low environmental impact
*Suitable for harsh conditions
*Low sensitivity
*Versatile



SYNTHESIS OF ETHYLENEDIAMINE:
Ethylenediamine is manufactured by reacting ammonia and 1,2-dichloroethane.
The reaction yields the mixture of ethylenediamine and the linear polyamines.
A simplified equation would be:
ClCH2CH2Cl + 4 NH3 → H2NCH2CH2NH2 + 2 NH4Cl



WHAT IS ETHYLENEDIAMINE AND WHERE IS ETHYLENEDIAMINE FOUND?
Ethylenediamine is a potent sensitiser used in topical medications, particularly antibiotic/steroid creams for its chemical stabilizing properties.
Ethylenediamine has been commonly found that individuals who show a positive patch test reaction to ethylenediamine have used, a popular broad-spectrum antifungal/steroid cream, or one of its generic preparations.
Ethylenediamine is not used in ointment preparations and is rarely found in cosmetics and toiletries.



SYNTHESIS OF ETHYLENEDIAMINE:
Ethylenediamine is produced industrially by treating 1,2-dichloroethane with ammonia under pressure at 180 °C in an aqueous medium.
In this reaction hydrogen chloride is generated, which forms a salt with the amine.
The amine is liberated by addition of sodium hydroxide and can then be recovered by rectification.
Diethylenetriamine (DETA) and triethylenetetramine (TETA) are formed as by-products.

Another industrial route to ethylenediamine involves the reaction of ethanolamine and ammonia.
This process involves passing the gaseous reactants over a bed of nickel heterogeneous catalysts.
Ethylenediamine can be produced in the lab by the reaction of ethylene glycol and urea.
Ethylenediamine can be purified by treatment with sodium hydroxide to remove water followed by distillation.



COORDINATION CHEMISTRY OF ETHYLENEDIAMINE:
Ethylenediamine is a well-known bidentate chelating ligand for coordination compounds, with the two nitrogen atoms donating their lone pairs of electrons when ethylenediamine acts as a ligand.

Ethylenediamine is often abbreviated "en" in inorganic chemistry.
The complex [Co(ethylenediamine)3]3+ is an archetypical chiral tris-chelate complex.
The salen ligands, some of which are used in catalysis, are derived from the condensation of salicylaldehydes and ethylenediamine.

-Related ligands:
Related derivatives of ethylenediamine include ethylenediaminetetraacetic acid (EDTA), tetramethylethylenediamine (TMEDA), and tetraethylethylenediamine (TEEDA).
Chiral analogs of ethylenediamine include 1,2-diaminopropane and trans-diaminocyclohexane.



PRECURSOR TO PHARMACEUTICALS AND AGRICHEMICALS:
Numerous bio-active compounds contain the N-CH2-CH2-N linkage, including aminophylline and some antihistamines. Salts of ethylenebisdithiocarbamate are commercially significant fungicides under the brandnames Maneb, Mancozeb, Zineb, and Metiram. Some imidazoline-containing fungicides are derived from ethylenediamine.



PRECURSOR TO CHELATING AGENTS:
The most prominent derivative of Ethylenediamine is EDTA, which is derived from ethylenediamine via a Strecker synthesis involving cyanide and formaldehyde. Hydroxyethylethyelenediamine is another commercially significant chelating agent.
The salen ligands, derived from the condensation of salicaldehydes and ethylenediamine, are popular chelating agents in the research laboratory although not commercially significant.



TETRAACETYLETHYLENEDIAMINE:
The bleaching activator tetraacetylethylenediamine is generated from ethylenediamine.
The derivative N,N-ethylenebis(stearamide) (EBS) is a commercially significant mold-release agent and a surfactant in gasoline and motor oil.



ROLE IN POLYMERS:
Ethylenediamine, by virtue of its bifunctionality (i.e. it contains two reactive amines) is widely used in diverse polyester formulations. Condensates derived from formaldehyde are plasticizers. It is widely used in the production of polyurethane fibers. The PAMAM class of dendrimers are derived from ethylenediamine.



ETHYLENEAMINES:
Ethylenediamine is the first member of the so-called polyethylene amines, other members being:
Diethylenetriamine, abbreviated dien or DETA, (H2N-CH2CH2-NH-CH2CH2-NH2, an analog of diethylene glycol)
Triethylenetetramine, abbreviated trien or TETA, (H2N-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH2)

Tetraethylenepentamine, abbreviated TEPA, (H2N-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH2),
Pentaethylenehexamine, abbreviated PEHA, (H2N-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH2), up to polyethylene amine. Similarly piperazine is an analogue of dioxane.

Related diamines:
In terms of quantities produced, ethylenediamine is the most significant diamine (aside from diaminohexane, which is a precursor to Nylon 66).
Related derivatives of ethylenediamine include tetramethylethylenediamine, abbreviated (TMEDA), (CH3)2N-CH2CH2-N(CH3)2 and tetraethylethylenediamine, abbreviated (TEEDA), (C2H5)2N-CH2CH2-N(C2H5)2



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENEDIAMINE:
Molecular Weight: 60.10
XLogP3: -2
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 1
Exact Mass: 60.068748264
Monoisotopic Mass: 60.068748264
Topological Polar Surface Area: 52 Ų
Heavy Atom Count: 4
Formal Charge: 0
Complexity: 6
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Flash point: 34 °C (93 °F; 307 K)
Autoignition temperature: 385 °C (725 °F; 658 K)
Explosive limits: 2.7–16%
Heat capacity (C): 172.59 J K−1 mol−1
Std molar entropy (S⦵298): 202.42 J K−1 mol−1
Std enthalpy of formation (ΔfH⦵298): −63.55–−62.47 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): −1.8678–−1.8668 MJ mol−1
Chemical formula: C2H8N2
Molar mass: 60.100 g·mol−1
Appearance: Colorless liquid
Odor: Ammoniacal
Density: 0.90 g/cm3
Melting point: 8 °C (46 °F; 281 K)
Boiling point: 116 °C (241 °F; 389 K)
Solubility in water: miscible
log P: −2.057
Vapor pressure: 1.3 kPa (at 20 °C)
Henry's law constant (kH): 5.8 mol Pa−1 kg−1
Magnetic susceptibility (χ): -46.26·10−6 cm3/mol
-76.2·10−6 cm3/mol (HCl salt)
Refractive index (nD): 1.4565

Formula: C2H8N2
Formula mass: 60.10
Melting point, °C: 8.5
Boiling point, °C: 117
Vapor pressure, mmHg: 16 (25 C)
Vapor density (air=1): 2.07
Saturation Concentration: 1.3% at 20 C
Evaporization number: 0.91 (butyl acetate = 1)
Critical temperature: 340
Critical pressure: 66.19
Density: 0.898 g/cm3 (20 C)
Solubility in water: Miscible
Viscosity: 1.54 cp (25 C)
Surface tension: 40.77 g/s2 (20 C)
Refractive index: 1.454 (20 C)
Dipole moment: 1.83 D (25 C)
Dielectric constant: 16 (18 C)

pKa/pKb: 4.11 (pKb)
Partition coefficient, pKow: -2.04
Heat of fusion: 19.3 kJ/mol
Heat of vaporization: 46.9 kJ/mol
Heat of combustion: -1890 kJ/mol
Physical state: liquid
Color: colorless
Odor: amine-like
Melting point/freezing point
Melting point/range: 8,5 °C
Initial boiling point and boiling range: 118 °C
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 17 %(V)
Lower explosion limit: 2 %(V)
Flash point: 38 °C - closed cup

Autoignition temperature: 405 °C
Decomposition temperature: > 120 °C
pH: 12,2 at 100 g/l at 20 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 1,265 - 1,725 mPa.s at 25 °C
Water solubility 1.000 g/l - miscible
Partition coefficient: n-octanol/water:
log Pow: -2,04 - Bioaccumulation is not expected., (Lit.)
Vapor pressure 12 hPa at 20 °C
Density 0,899 g/mL at 25 °C
Relative density No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none

Other safety information:
Relative vapor density: 2,07 - (Air = 1.0)
CAS number: 107-15-3
EC index number: 612-006-00-6
EC number: 203-468-6
Hill Formula: C₂H₈N₂
Chemical formula: H₂NCH₂CH₂NH₂
Molar Mass: 60.10 g/mol
HS Code: 2921 21 00
Density: 0.897 g/cm3 (20 °C)
Explosion limit: 2 - 17 %(V)
Flash point: 38 °C
Ignition temperature: 405 °C
Melting Point: 11.1 °C
pH value: 12.2 (100 g/l, H₂O, 20 °C)
Vapor pressure: 12 hPa (20 °C)

Physical description: Colorless, viscous liquid with an ammonia-like odor.
Boiling point: 241°F
Molecular weight: 60.1
Freezing point/melting point: 47°F
Vapor pressure: 11 mmHg
Flash point: 93°F
Vapor density: 2.07
Specific gravity: 0.91
Ionization potential: 8.60 eV
Lower explosive limit (LEL): 4.2%
Upper explosive limit (UEL): 14.4%
NFPA health rating: 3
NFPA fire rating: 2
NFPA reactivity rating: 0
NFPA special instruction: 0



FIRST AID MEASURES of ETHYLENEDIAMINE:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most), avoid vomiting.
Call a physician immediately.
Do not attempt to neutralise.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ETHYLENEDIAMINE:
-Personal precautions, protective equipment and emergency procedures:
*Advice for non-emergency personnel:
Ensure adequate ventilation.
Evacuate the danger area, observe emergency procedures, consult an expert.
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ETHYLENEDIAMINE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENEDIAMINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 240 min
*Body Protection:
Flame retardant antistatic protective clothing.
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ETHYLENEDIAMINE:
-Precautions for safe handling:
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Handle and store under inert gas.



STABILITY and REACTIVITY of ETHYLENEDIAMINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
Absorbs carbon dioxide (CO2) from air.
-Possibility of hazardous reactions:
No data available



SYNONYMS:
ethylenediamine
Ethane-1,2-diamine
107-15-3
1,2-Ethanediamine
1,2-Diaminoethane
Ethylene diamine
Ethylendiamine
edamine
Dimethylenediamine
1,2-Ethylenediamine
Aethaldiamin
Aethylenediamin
Ethyleendiamine
Ethylene-diamine
beta-Aminoethylamine
1,2-Diaminoaethan
Algicode 106L
Amerstat 274
1,2-Diamino-ethaan
1,2-Diamino-ethano
Ethylenediamine [JAN]
NCI-C60402
Edamine [INN]
ETHYLENEDIAMINE ANHYDROUS
CHEBI:30347
CHEMBL816
H2NCH2CH2NH2
ETHANE,1,2-DIAMINO
60V9STC53F
27308-78-7
DTXSID5021881
2-Aminoethylammonium chloride
1, 2-Diaminoethane
NCGC00091527-01
1,2-diaminoethane phase II
EN
DTXCID501881
1,2-diaminoethane phase I beta
Aethaldiamin [German]
Caswell No. 437
1,2-diaminoethane phase I alpha
Ethane-1,2-diammonium bromide
CAS-107-15-3
Ethylenediamine, ReagentPlus(R), >=99%
CCRIS 5224
HSDB 535
Aminophylline Injection
EINECS 203-468-6
UN1604
EPA Pesticide Chemical Code 004205
Ethylenediamine [USP:JAN]
BRN 0605263
UNII-60V9STC53F
ethylenediarnine
AI3-24231
2-aminoethylamine
ethylene di amine
1,4-diazabutane
1,2-diaminoethan
ethylene - diamine
EDN
1,2-ethylendiamine
MFCD00008204
1,2-diamino-ethane
ethane 1,2-diamine
N,N'-ethylenediamine
Ethylenediamine, 8CI
1,2-ethylene diamine
1,2-ethylene-diamine
Ethylenediamine [UN1604]
.beta.-Aminoethylamine
ethane-1, 2-diamine
N,N'-ethylene diamine
Ethylenediamine, BioXtra
Epitope ID:117724
EC 203-468-6
ETHYLENEDIAMINE [II]
ETHYLENEDIAMINE [MI]
4-04-00-01166 (Beilstein Handbook Reference)
Ethylenediamine (USP/JP15)
Ethylenediamine (USP/JP17)
ETHYLENEDIAMINE [HSDB]
ETHYLENEDIAMINE [INCI]
BDBM7972
NH2(CH2)2NH2
ETHYLENEDIAMINE [MART.]
ETHYLENEDIAMINE [WHO-DD]
624-59-9 (di-hydrobromide)
333-18-6 (di-hydrochloride)
5700-49-2 (di-hydriodide)
Ethylenediamine, analytical standard
STR00309
Tox21_111145
Tox21_201202
STL264241
ZINC37253587
ETHYLENEDIAMINE [EP MONOGRAPH]
AKOS000118850
DB14189
ETHYLENEDIAMINE [USP MONOGRAPH]
UN 1604
Ethylenediamine, for synthesis, 99.0%
NCGC00091527-02
NCGC00258754-01
BP-20367
Ethylenediamine [UN1604]
E0077
E0081
EN300-19398
D01114
Ethylenediamine, SAJ special grade, >=99.0%
Ethylenediamine, meets USP testing specifications
Ethylenediamine, Vetec(TM) reagent grade, >=98%
Q411362
J-001723
Ethylenediamine, purified by redistillation, >=99.5%
TIZANIDINE HYDROCHLORIDE IMPURITY H [EP IMPURITY]
Z104473714
Ethylenediamine, puriss. p.a., absolute, >=99.5% (GC)
1.3 mmol/g loading, 1 % cross-linked with divinylbenzene
Ethane-1,2-diamine
Edamine
1,2-Diaminoethane
1,2-Diaminoethane
1,2-Ethanediamine
Ethylenediamine (anhydrous)
1,2-Ethanediamine
β-Aminoethylamine
Dimethylenediamine
Ethane-1,2-diamine
1,2-Diaminoethane
1,2-Ethylenediamine
H2NCH2CH2NH2
Aethaldiamin
Aethylenediamin
1,2-Diaminoaethan
1,2-Diamino-ethaan
1,2-Diamino-ethano
Ethyleendiamine
Ethylendiamine
NCI-C60402
UN 1604


ETHYLENEDIAMINE (EDA)

Ethylenediamine (EDA), also known as 1,2-diaminoethane, is an organic compound with the chemical formula C2H8N2.
Ethylenediamine (EDA) is a colorless liquid with an ammonia-like odor.
Ethylenediamine (EDA) is a simple diamine, meaning it contains two amino groups (-NH2) separated by two carbon atoms.

CAS Number: 107-15-3
EC Number: 203-468-6

Ethylenediamine, EDA, 1,2-diaminoethane, 1,2-ethanediamine, 1,2-Diaminoethane, Ethane-1,2-diamine, 1,2-Ethylenediamine, Aethaldiamine, 1,2-Diazaethane, Ethylamine, Diaminoethane, Ethylenediamin, Glycolamine, Ethane-1,2-diyldiamine, α,ω-Diaminoethane, H2NCH2CH2NH2, Dimethylethylenediamine, 1,2-Diaminethylethane, Ethyleneimine, N,N'-Bis(2-aminoethyl)ethane-1,2-diamine, Ethylene Diamine, H2N(CH2)2NH2, Ethylamine, Diaminoethylene, 1,2-Ethandiamine, 1,2-エチレンジアミン, Diaminethylethane



APPLICATIONS


Ethylenediamine (EDA) is commonly used as a chelating agent in the formulation of metal ion complexes for various industrial processes.
Ethylenediamine (EDA) is utilized in the production of chelating agents such as EDTA (ethylenediaminetetraacetic acid) and DTPA (diethylenetriaminepentaacetic acid).
Ethylenediamine (EDA) is employed in the purification of water by complexing with metal ions and removing them from solution.

Ethylenediamine (EDA) serves as a precursor for the synthesis of polyamines, which are used as curing agents in epoxy resins and polyurethane foams.
Ethylenediamine (EDA) is an essential component in the manufacture of fungicides, herbicides, and insecticides for agricultural applications.

Ethylenediamine (EDA) is used in the production of pharmaceuticals, including antihistamines, antifungal agents, and local anesthetics.
Ethylenediamine (EDA) is employed as a catalyst in the synthesis of specialty chemicals and pharmaceutical intermediates.

Ethylenediamine (EDA) serves as a raw material in the synthesis of polymers such as nylon, polyamides, and polyurethanes.
Ethylenediamine (EDA) is utilized in the preparation of adhesives, coatings, and sealants for various industrial applications.
Ethylenediamine (EDA) acts as a solvent in the extraction of natural products and in the formulation of specialty chemicals.

Ethylenediamine (EDA) is used in the textile industry for dyeing and printing processes due to its ability to form stable complexes with metal ions.
Ethylenediamine (EDA) serves as a corrosion inhibitor in metalworking fluids, protecting metal surfaces from oxidation and rust.

Ethylenediamine (EDA) is employed in the synthesis of surfactants and detergents for use in cleaning and personal care products.
Ethylenediamine (EDA) serves as a complexing agent in the formulation of metal plating baths for electroplating processes.
Ethylenediamine (EDA) is utilized in the production of fuel additives, lubricants, and hydraulic fluids to improve performance and stability.

Ethylenediamine (EDA) acts as a pH regulator and stabilizer in industrial processes such as paper manufacturing and wastewater treatment.
Ethylenediamine (EDA) is used in the synthesis of ion exchange resins for water softening and purification applications.

Ethylenediamine (EDA) serves as a reagent in analytical chemistry for the determination of metal ions and complexometric titrations.
Ethylenediamine (EDA) is employed in the synthesis of specialty chemicals used in the electronics industry for semiconductor manufacturing.
Ethylenediamine (EDA) serves as a catalyst in the production of polyurethane elastomers and foams for automotive and construction applications.

Ethylenediamine (EDA) is utilized in the production of rubber chemicals, antioxidants, and vulcanization accelerators.
Ethylenediamine (EDA) serves as a stabilizer and antioxidant in the formulation of polymers and plastics to prevent degradation during processing and storage.

Ethylenediamine (EDA) is used in the synthesis of adhesives and sealants for bonding substrates in construction and automotive applications.
Ethylenediamine (EDA) serves as a reagent in the production of dyes, pigments, and photographic chemicals for printing and imaging applications.
Ethylenediamine (EDA) is an important chemical intermediate with diverse applications in various industries, contributing to the development of innovative materials and products.

Ethylenediamine (EDA) is used in the synthesis of ion-exchange resins for chromatography and purification applications in analytical chemistry.
Ethylenediamine (EDA) serves as a complexing agent in the formulation of metal complexes used as catalysts in organic synthesis.
Ethylenediamine (EDA) is employed in the preparation of metal nanoparticles and nanocomposites for catalysis and material science applications.

Ethylenediamine (EDA) is used in the production of specialty chemicals such as corrosion inhibitors, antifoaming agents, and scale inhibitors for industrial processes.
Ethylenediamine (EDA) is utilized in the formulation of adhesives and sealants for bonding substrates in aerospace and marine applications.

Ethylenediamine (EDA) serves as a component in the synthesis of crosslinking agents for the modification of polymers and elastomers.
Ethylenediamine (EDA) is employed in the synthesis of specialty resins for coatings, inks, and varnishes for architectural and industrial applications.

Ethylenediamine (EDA) serves as a chemical intermediate in the production of flavors, fragrances, and pharmaceutical excipients.
Ethylenediamine (EDA) is used in the formulation of metalworking fluids for lubrication and cooling during machining processes.
Ethylenediamine (EDA) serves as a reagent in the production of specialty gases, including ethylenediamine dinitrate (EDDN) for explosives and propellants.

Ethylenediamine (EDA) is employed in the synthesis of cationic surfactants and softeners for use in fabric softeners and textile finishing agents.
Ethylenediamine (EDA) serves as a crosslinking agent in the production of rubber vulcanizates for tire manufacturing and automotive applications.
Ethylenediamine (EDA) is used in the formulation of antifreeze and coolant additives for automotive and industrial cooling systems.

Ethylenediamine (EDA) serves as a stabilizer and dispersant in the formulation of emulsions and suspensions for pharmaceutical and cosmetic applications.
Ethylenediamine (EDA) is employed in the production of specialty polymers such as polyamide-imides and polyethyleneimines for high-performance applications.
Ethylenediamine (EDA) serves as a reagent in the synthesis of urea-formaldehyde resins for use in wood adhesives and composite materials.

Ethylenediamine (EDA) is utilized in the formulation of cleaning agents and degreasers for industrial and household applications.
Ethylenediamine (EDA) serves as a catalyst in the production of polyols and isocyanates for the synthesis of polyurethane foams and coatings.

Ethylenediamine (EDA) is employed in the synthesis of pharmaceutical intermediates such as benzylpenicillin and ethylenediaminetetraacetonitrile.
Ethylenediamine (EDA) serves as a crosslinking agent in the production of dental materials such as impression compounds and denture adhesives.

Ethylenediamine (EDA) is used in the formulation of inkjet inks and toners for printing and imaging applications.
Ethylenediamine (EDA) serves as a reagent in the synthesis of specialty polymers such as polycarboxylates for water treatment and concrete additives.

Ethylenediamine (EDA) is employed in the formulation of deicing agents and antifreeze solutions for aircraft and runway maintenance.
Ethylenediamine (EDA) serves as a component in the synthesis of pharmaceutical active ingredients such as antiviral drugs and anticancer agents.
Ethylenediamine (EDA) is an essential chemical with diverse applications across various industries, contributing to the development of advanced materials, technologies, and products.



DESCRIPTION


Ethylenediamine (EDA), also known as 1,2-diaminoethane, is an organic compound with the chemical formula C2H8N2.
Ethylenediamine (EDA) is a colorless liquid with an ammonia-like odor.
Ethylenediamine (EDA) is a simple diamine, meaning it contains two amino groups (-NH2) separated by two carbon atoms.

Ethylenediamine (EDA) is primarily used as a building block in the production of various chemicals, including chelating agents, polyurethane resins, fuel additives, and pharmaceuticals.
Ethylenediamine (EDA) is a versatile compound with strong nucleophilic properties, making it useful in many chemical reactions.

Ethylenediamine (EDA) is a colorless, viscous liquid at room temperature.
Ethylenediamine (EDA) has a distinctive ammonia-like odor, which is characteristic of primary amines.

Ethylenediamine (EDA) is highly soluble in water, alcohol, and other polar solvents.
Ethylenediamine (EDA) is hygroscopic, meaning it readily absorbs moisture from the air.

Ethylenediamine has a boiling point of approximately 116°C and a melting point of about −8°C.
Ethylenediamine (EDA) is miscible with many organic solvents, making it useful in various chemical reactions.

Ethylenediamine (EDA) is commonly used as a chelating agent to bind metal ions in solution.
Ethylenediamine (EDA) forms stable complexes with transition metals such as copper, iron, and nickel.

Ethylenediamine (EDA) is a versatile building block in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals.
Ethylenediamine (EDA) serves as a precursor for the synthesis of polyamines and polyamides.
Ethylenediamine (EDA) can act as a ligand in coordination chemistry, forming coordination complexes with metal ions.

Ethylenediamine (EDA) is used in the production of polyurethane foams, resins, and coatings.
Ethylenediamine (EDA) is employed as a curing agent for epoxy resins, enhancing their mechanical properties.
In the petroleum industry, EDA is used as a selective solvent for the removal of hydrogen sulfide and carbon dioxide from natural gas streams.

Ethylenediamine (EDA) is also utilized in the purification of hydrocarbon streams and as a corrosion inhibitor.
Ethylenediamine (EDA) is employed as a stabilizer and pH adjuster in industrial processes such as metal plating and textile manufacturing.
Ethylenediamine (EDA) serves as a precursor for the synthesis of ethylenediaminetetraacetic acid (EDTA), a widely used chelating agent in analytical chemistry.

Ethylenediamine (EDA) is an important component in the production of herbicides, fungicides, and insecticides.
Ethylenediamine (EDA) exhibits strong nucleophilic properties, facilitating reactions such as alkylation, acylation, and reductive amination.
Ethylenediamine (EDA) is used in the preparation of specialty chemicals, surfactants, and detergents.

Ethylenediamine (EDA) plays a role in the synthesis of dyes, pigments, and photographic chemicals.
Ethylenediamine can react with acids to form ethylenediammonium salts, which are used as ion-exchange resins and in the production of fertilizers.

In the pharmaceutical industry, EDA is employed in the synthesis of antihistamines, local anesthetics, and antifungal agents.
Due to its alkaline nature, ethylenediamine can cause skin and eye irritation upon contact and should be handled with caution.
Ethylenediamine (EDA) is a versatile compound with diverse applications in various industries, from chemical manufacturing to pharmaceuticals and beyond.



PROPERTIES


Physical Properties:

Appearance: Clear, colorless liquid
Odor: Ammonia-like odor
Density: 0.899 g/cm³ (at 20°C)
Melting Point: −8.5°C
Boiling Point: 116.8°C
Flash Point: 36°C (closed cup)
Vapor Pressure: 7.4 mmHg (at 20°C)
Solubility in Water: Completely miscible
Vapor Density: 2.6 (air = 1)
Refractive Index: 1.455 (at 20°C)


Chemical Properties:

Chemical Formula: C2H8N2
Molecular Weight: 60.10 g/mol
Structure: Ethylenediamine consists of two amino groups (-NH2) separated by two carbon atoms (-CH2-CH2-).
Solubility: Soluble in water, alcohol, and polar solvents
pH: Basic (alkaline) in aqueous solution
Acidity/Basicity: Exhibits basic properties due to the presence of amino groups
Reactivity: Ethylenediamine is a strong nucleophile and can undergo reactions such as alkylation, acylation, and complex formation with metal ions.
Stability: Generally stable under normal conditions, but may degrade upon exposure to heat, light, or air.
Flammability: Flammable liquid, forms flammable vapor-air mixtures.
Corrosivity: Can cause corrosion to metals upon prolonged contact.
Toxicity: Ethylenediamine is toxic if ingested and can cause skin and eye irritation upon contact.
Biodegradability: Biodegradable under aerobic conditions, but persistence in the environment may vary.
Hazardous Polymerization: Does not occur under normal conditions.
Autoignition Temperature: 390°C
Explosive Limits: Lower Explosive Limit (LEL) - 3.3% (Volume), Upper Explosive Limit (UEL) - 15.7% (Volume)



FIRST AID


Inhalation:

If Ethylenediamine vapors are inhaled and respiratory irritation occurs, immediately move the affected person to fresh air.
Allow the individual to rest in a well-ventilated area and provide them with oxygen if breathing difficulties persist.
If the person is not breathing or shows signs of respiratory distress, administer artificial respiration. Seek medical attention promptly.
Keep the person warm and comfortable. Do not leave them unattended.


Skin Contact:

In case of skin contact with Ethylenediamine, immediately remove contaminated clothing and shoes.
Rinse the affected area with plenty of water for at least 15 minutes to remove any residual chemical.
Wash the skin thoroughly with mild soap and water to remove any remaining traces of Ethylenediamine.
If skin irritation, redness, or rash develops, seek medical advice promptly.
Do not apply ointments or creams to the affected area unless instructed by medical personnel.


Eye Contact:

If Ethylenediamine comes into contact with the eyes, immediately flush the eyes with gently flowing water for at least 15 minutes.
Hold the eyelids open to ensure thorough rinsing and remove any contact lenses if present and easily removable.
Seek immediate medical attention, even if the affected person does not experience immediate symptoms.
Do not rub the eyes, as this may exacerbate irritation and cause further damage.


Ingestion:

If Ethylenediamine is ingested accidentally and the person is conscious, rinse their mouth thoroughly with water and encourage them to drink water or milk to dilute the chemical.
Do not induce vomiting unless instructed to do so by medical personnel, especially if the individual is unconscious or experiencing convulsions.
Seek medical advice immediately, and provide the healthcare provider with information about the ingested substance, including its name, concentration, and the amount ingested.
Monitor the person for signs of gastrointestinal distress, such as nausea, vomiting, or abdominal pain, and seek medical attention promptly if symptoms worsen or persist.


General Precautions:

Always handle Ethylenediamine with care and wear appropriate personal protective equipment (PPE) such as gloves, goggles, and protective clothing to prevent skin and eye contact.
Avoid breathing in vapors or mists of Ethylenediamine. Use local exhaust ventilation or respiratory protection if necessary.
Keep containers tightly closed when not in use and store them in a cool, dry, well-ventilated area away from sources of heat, ignition, and incompatible substances.
In case of a spill, contain the area and prevent further release of the chemical into the environment. Clean up spills promptly using appropriate absorbent materials and dispose of waste according to local regulations.



HANDLING AND STORAGE


Handling:

When handling Ethylenediamine (EDA), wear appropriate personal protective equipment (PPE) including chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact.
Avoid breathing in vapors or mists of Ethylenediamine.
Use local exhaust ventilation or respiratory protection if necessary to control airborne exposure.
Ensure adequate ventilation in the work area to minimize the buildup of vapors or fumes. Use explosion-proof equipment in areas where flammable vapors may be present.
Prevent contact with incompatible materials such as strong acids, oxidizing agents, and alkalis, as they may react violently with Ethylenediamine and release hazardous gases.
Use caution when transferring or pouring Ethylenediamine to prevent spills and splashes. Use appropriate tools and equipment such as funnels or pumps to minimize contact with the chemical.
Keep containers tightly closed when not in use to prevent contamination and minimize exposure to air and moisture.
Avoid contact with skin, eyes, and clothing.
In case of contact, follow appropriate first aid measures and rinse thoroughly with water.
Do not eat, drink, or smoke while handling Ethylenediamine, and wash hands thoroughly after handling to prevent accidental ingestion.
Avoid prolonged or repeated exposure to Ethylenediamine, as it may cause skin irritation, sensitization, or allergic reactions in some individuals.
Handle Ethylenediamine with care to prevent spills, leaks, and releases into the environment.
Clean up spills promptly using appropriate absorbent materials and dispose of waste according to local regulations.


Storage:

Store Ethylenediamine in a cool, dry, well-ventilated area away from sources of heat, ignition, and direct sunlight.
Keep containers tightly closed and upright to prevent leakage or spills. Store larger quantities in suitable containers with secondary containment to contain spills.
Store Ethylenediamine away from incompatible materials such as strong acids, oxidizing agents, and alkalis to prevent reactions or contamination.
Ensure storage areas are equipped with appropriate firefighting equipment and spill containment materials in case of emergencies.
Follow local regulations and guidelines for the storage of chemicals, including any specific requirements for the storage of Ethylenediamine.
Keep storage areas clean and free from clutter to minimize the risk of spills and accidents.
Check containers regularly for signs of damage or deterioration and replace any damaged or compromised containers promptly.
Store Ethylenediamine in its original packaging or labeled containers to ensure proper identification and traceability.
Separate Ethylenediamine from incompatible materials by storing them in separate areas or using barriers to prevent contact.
Monitor storage conditions regularly to ensure compliance with safety guidelines and to prevent the buildup of hazardous conditions.

ETHYLENEDIAMINE (EDA)
EDTA, DISODIUM; EDTA, Disodium Salt Dihydrate; Ethylenediaminetetraacetic acid disodium salt dihydrate; Ethanediylbis(N-(carboxymethyl)glycine) disodium salt; Disodium dihydrogen ethylenediaminetetraacetate; Versene disodium salt;cas no: 139-33-3
ETHYLENEDIAMINETETRAACETIC ACID (EDTA)
Ethylenediaminetetraacetic Acid (EDTA) is a colorless crystalline solid.
Ethylenediaminetetraacetic Acid (EDTA) is slightly soluble in water.


CAS Number: 60-00-4 (free acid)
6381-92-6 (dihydrate disodium salt)
EC Number: 200-449-4
MDL number: MFCD00003541
Linear Formula: (HO2CCH2)2NCH2CH2N(CH2CO2H)2
Molecular Formula : C10H16N2O8



SYNONYMS:
(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid, Edathamil, (Ethylenedinitrilo)tetraacetic acid, Ethylenedinitrilotetraacetic acid, EDTA, EDTA, Edetic acid, Ethylenediaminetetraacetic acid, 60-00-4, Edathamil, Sequestrol, Versene, Havidote, Titriplex, EDTA acid, Versene acid, Endrate, Cheelox, Gluma cleanser, Sequestrene aa, Sequestric acid, Warkeelate acid, Komplexon ii, Tetrine acid, Quastal Special, Metaquest A, Trilon bw, Titriplex II, Hamp-ene acid, Cheelox BF acid, Trilon BS, Celon A, Celon ATH, Chelest 3A, Questex 4H, (Ethylenedinitrilo)tetraacetic acid, Chemcolox 340, Universne acid, EDTA (chelating agent), Dissolvine E, Vinkeil 100, Nullapon B acid, Nullapon bf acid, Nervanaid B acid, Perma kleer 50 acid, Clewat TAA, Ethylenedinitrilotetraacetic acid, Acide edetique, Acido edetico, Acidum edeticum, Caswell No. 438, Versenate, ICRF 185, Calcium disodium versenate, Ethylenebisiminodiacetic acid, Ethylenediamine-N,N,N',N'-tetraacetic acid, SEQ 100, YD 30, Disodium EDTA, CCRIS 946, Chelaton 3, Ethylenebis(iminodiacetic acid), HSDB 809, Acide ethylenediaminetetracetique, ETHYLENEDIAMINE TETRAACETIC ACID, Cheladrate, Edetate calcium, Edetate disodium, Acide edetique [INN-French], Acido edetico [INN-Spanish], Acidum edeticum [INN-Latin], Acetic acid, (ethylenedinitrilo)tetra-, EPA Pesticide Chemical Code 039101, Ethylenediaminetetraacetate, Kyselina ethylendiamintetraoctova, Tricon bw, Acid, Edetic, AI3-17181, H4edta, 3,6-Diazaoctanedioic acid, 3,6-bis(carboxymethyl)-, Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, 470462-56-7, EINECS 200-449-4, UNII-9G34HU7RV0, Edetate, BRN 1716295, Edta disodium, Versene-13C4, 9G34HU7RV0, Disodium edetate, Disodium versene, Endrate disodium, Sodium versenate, Edetic acid disodium salt, Kyselina ethylendiamintetraoctova [Czech], Acetic acid, 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetrakis-, Acide ethylenediaminetetracetique [French], Disodium edetate dihydrate, DTXSID6022977, Metaquest B, N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine), CHEBI:42191, ethylene diamine tetraacetic acid, Kiresuto B, Chelaplex III, Diso-Tate, Titriplex III, 2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid, Chelaton III, Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine), Versene NA, Triplex III, Disodium versenate, Edathamil disodium, Trilon BD, Versene Na2, Disodium sequestrene, Disodium tetracemate, EDTA disodium salt, MFCD00003541, EDTA, ion(4-), CHEMBL858, Sequestrene sodium 2, 2,2',2'',2'''-(ethane-1,2-diylbis(azanetriyl))tetraacetic acid, 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid, {[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID, Disodium salt of EDTA, ethylenediamine tetracetic acid, DTXCID902977, Perma Kleer Di Crystals, (ethylenedinitrilo)tetraacetic acid, ion(4-), Calcium disodium versenate (TN), ethylene-diamine tetraacetic acid, 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetic acid, EC 200-449-4, 4-04-00-02449 (Beilstein Handbook Reference), EDT, Ethylenediaminetetraacetic acid disodium salt, Edetate calcium disodium (USP), Sequestrene Na2, Trilon B, Selekton B2, Disodium ethylenediaminetetraacetate, (ethane-1,2-diyldinitrilo)tetraacetic acid, EDETIC ACID (II), EDETIC ACID [II], Perma kleer 50 crystals disodium salt, Disodium (ethylenedinitrilo)tetraacetate, Disodium ethylenediaminetetraacetic acid, EDETIC ACID (MART.), EDETIC ACID [MART.], CaEDTA, N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycine], CBC 50152966, DR-16133, Ethylenediaminetetraacetate, disodium salt, EDETIC ACID (USP-RS), EDETIC ACID [USP-RS], ANTICOAGULANT ETHYLENEDIAMINE TETRAACETIC ACID, Disodium diacid ethylenediaminetetraacetate, D'E.d.t.a. disodique, Disodium (ethylenedinitrilo)tetraacetic acid, 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate, Disodium dihydrogen ethylenediaminetetraacetate, Ethylenediaminetetraacetic acid, disodium salt, ANTICOAGULANT ETHYLENEDIAMINE TETRAACETIC ACID (EDTA), Disodium ethylenediamine-N,N,N',N'-tetraacetate, EDETIC ACID (EP MONOGRAPH), EDETIC ACID [EP MONOGRAPH], Disodium dihydrogen(ethylenedinitrilo)tetraacetate, 139-33-3, C10H16N2O8, NSC2760, NCGC00159485-02, 6381-92-6, disodium-edta, Edetic, Edetic acid [INN:BAN:NF], ((-(bis-carboxymethyl-amino)-ethyl)-carboxymethyl-amino)-acetic acid, (Ethylenedinitrilo)tetraacetic acid, disodium salt, Versenic Acid, Acid, Ethylenediaminetetraacetic, ([2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino)-acetic acid, {[2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetic acid, 2-(2-[bis(carboxymethyl)amino]ethylamino)acetic acid, Calcium Disodium Edetate (JAN), ethylenediamine tetra-acetic acid, Techrun DO, Acid, Ethylenedinitrilotetraacetic, EDTA, anhydrous, Zonon AO, EDTA, free acid, EDTA, free base, ACETIC ACID, (ETHYLENEDINITRILO)TETRA-, DISODIUM SALT, Versene acid (TN), ethylenediaminetetraacetic acid (edta), Caswell No 438, Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl))-, Ethylenediamine-tetraacetic acid (EDTA), Acroma DH 700, Spectrum_001018, Edetic acid (NF/INN), EDTA [VANDF], Spectrum2_000003, Spectrum3_000412, Spectrum4_000531, Spectrum5_000955, EDTA [INCI], Edetic acid [BAN:INN], EDETIC ACID [INN], EDTA [MI], EDETIC ACID [HSDB], EDTA, anhydrous ACS grade, ethylenediaminetetracetic acid, BSPBio_001964, Diaminoethanetetra-acetic acid, KBioGR_001161, KBioSS_001498, ethylenediaminetetraacetic-acid, MLS001249457, BIDD:ER0565, DivK1c_000777, EDETIC ACID [WHO-DD], SPBio_000005, ethylenediamine-tetraacetic acid, CHEBI:4735, KBio1_000777, KBio2_001498, KBio2_004066, KBio2_006634, KBio3_001184, (Ethylenedintrilo)tetraacetic acid, ethylen-ediamine tetra-acetic acid, ethylene diamine tetra acetic acid, NINDS_000777, (ethylenedinitrilo) tetraacetic acid, CS-B1827, HY-Y0682, STR08855, Tox21_202736, BDBM50330325, HB5135, s6350, AKOS001574475, Glycine, (N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, labeled with carbon-14, (ethane-1,2-diyldinitrilo)tetraacetate, DB00974, CAS-60-00-4, IDI1_000777, USEPA/OPP Pesticide Code: 039101, ETHYLENE BIS (IMINODIACETIC ACID), NCGC00159485-03, NCGC00159485-04, NCGC00260284-01, 688-55-1, AC-10615, SMR000058776, SBI-0051360.P003, E0084, Ethylenediaminetetraacetic acid, 2Na (EDTA), Ethylenediaminetetraacetic acid, LR, >=98%, NS00003929, EN300-71613, C00284, D00052, ethylene-N,N'-biscarboxymethyl-N,N'-diglycine, Ethylenediaminetetraacetic acid, p.a., 98.0%, AB00053468_03, Ethylenediaminetetraacetic acid, >=98.0% (KT), A832566, N,N'-1,2-Ethanediylbis(N-carboxymethyl)-glycine, N,N'-1,2-Ethanediylbis[N-(carboxymethyl)]glycine, N,N-1,2-Ethanediylbis[N-(carboxymethyl)]glycine, Q408032, SR-01000883946, Ethylenediaminetetraacetic Acid Sodium Salt Solution, Ethylenediaminetetraacetic acid, Cell Culture Reagent, J-610078, N, N-1,2-Ethanediylbis(N-(Carboxymethyl)Glycine), SR-01000883946-1, 3,6-Diazooctanedioic Acid, 3,6-bis(Carboxymethyl)-, 37C3C5E7-D921-445F-82D6-FEBF1AE5AEF5, Ethylenediaminetetraacetic acid, Electrophoresis Grade, Glycine, N, N'-1,2-Ethanediylbis-N-(Carboxymethyl), Z2588038976, Ethylenediaminetetraacetic acid, BioUltra, >=99.0% (KT), Ethylenediaminetetraacetic acid, 99.995% trace metals basis, Ethylenediaminetetraacetic acid, SAJ special grade, >=99.0%, Ethylenediaminetetraacetic acid, Vetec(TM) reagent grade, 98%, [{2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino]acetic acid, edta disodium salt, cal-ex decalcifier, buffer solution, ph 10.00, sodium di ethylenediamine tetraacetate dihydrate, ethylenediamine tetraacetic acid, disodium salt dihydrate, ethylenediamine tetraacetic acid, disodium salt, standard solution, sodium di ethylenediamine tetraacetate standard solution, ethylenedinitrilo tetraacetic acid disodium, dihydrate, reagent, Edetic Acid, N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine), Diaminoethanetetra-acetic acid, Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, Acetic acid, (ethylenedinitrilo)tetra-, Acide ethylenediaminetetracetique, Celon A, Celon ATH, Cheelox, Cheelox BF acid, Chemcolox 340, Complexon II, 3,6-Diazaoctanedioic acid, 3,6-bis(carboxymethyl)-, Edathamil, Edta, Edta acid, Endrate, Ethylenediamine-N,N,N',N'-tetraacetic acid, Ethylenedinitrilotetraacetic acid, Hamp-ene acid, Havidote, Komplexon ii, Kyselina ethylendiamintetraoctova, Metaquest A, Nervanaid B acid, Nullapon B acid, Nullapon BF acid, Perma kleer 50 acid, Questex 4H, SEQ 100, Sequestrene AA, Sequestric acid, Sequestrol, Tetrine acid, Titriplex, Tricon bw, Trilon BW, Versene, Versene acid, Vinkeil 100, Warkeelate acid, (Ethylenedintrilo)tetraacetic acid, EDTA, free base, EDTA, free acid, Trilon BS, ([2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino)-acetic acid, Titriplex II, YD 30, Quastal Special, Acetic acid, 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetrakis-, Gluma Cleanser, EDTA (chelating agent), Chelest 3A, ICRF 185, 2,2',2'',2'''-(Ethane-1,2-diyldinitrilo)te­traacetic acid, Dissolvine Z, 2-({2-[bis(carboxymet­hyl)amino]ethyl}(car­boxymethyl)ami­no)acetic acid, Diaminoethane-tetraacetic acid, Edetic acid, Ethylenedinitrilo-tetraacetic acid, Versene, EDTA, 2,2'',2'''',2''''''-(ethane-1,2-diylbis(azanetriyl))tetraacetic acid, Ethylenediaminetetraacetic acid, BioUltra, anhydrous, >=99% (titration), Glycine, N,N'-1, {2-ethanediylbis[N-(carboxymethyl)-,} disodium salt, {[2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetic acid(EDTA), 2-[2-[bis(2-hydroxy-2-oxoethyl)amino]ethyl-(2-hydroxy-2-oxoethyl)amino]ethanoic acid, Ethylenediaminetetraacetic acid, anhydrous, free-flowing, Redi-Dri(TM), >=98%, Ethylenediamine-N,N,N inverted exclamation mark ,N inverted exclamation mark -tetraacetic Acid-13C4 (|A-labels), Ethylenediaminetetraacetic acid, anhydrous, crystalline, BioReagent, suitable for cell culture, Ethylenediaminetetraacetic acid, anhydrous, free-flowing, powder, Redi-Dri(TM), ACS reagent, 99.4-100.6%, InChI=1/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20, N,N′-(Ethane-1,2-diyl)bis[N-(carboxymethyl)glycine], 2,2′,2′′,2′′′-(Ethane-1,2-diyldinitrilo)tetraacetic acid, EthyleneDiamineTetraAcetic acid, Diaminoethane-tetraacetic acid,



Ethylenediaminetetraacetic Acid (EDTA) is a colorless crystalline solid.
Ethylenediaminetetraacetic Acid (EDTA) is slightly soluble in water.
Ethylenediaminetetraacetic Acid (EDTA) is used in chemical analysis, to make detergents and cleaning compounds, and for many other uses.


Ethylenediaminetetraacetic Acid (EDTA) is a tetracarboxylic acid, an ethylenediamine derivative and a polyamino carboxylic acid.
Ethylenediaminetetraacetic Acid (EDTA) has a role as an antidote, a geroprotector, a chelator, a copper chelator and an anticoagulant.
Ethylenediaminetetraacetic Acid (EDTA) is a conjugate acid of an EDTA(2-).


Ethylenediaminetetraacetic Acid (EDTA) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 tonnes per annum.
Ethylenediaminetetraacetic Acid (EDTA) is the commonly used abbreviation for (Ethylene­dinitrilo)­tetra­acetic Acid (also called Ethylene­diamine­tetra­acetic Acid or Edetic Acid).


The Disodium salt of Ethylenediaminetetraacetic Acid (EDTA) is the most commonly used form of this versatile organic complexing agent, which is used for the determination of many metal ions either by direct titration or by back-titration.
Adjustment of reaction conditions, either by controlling the pH or by use of masking agents, and selection of the appropriate indicator permits a wide variety of metal ions to be determined using Ethylenediaminetetraacetic Acid (EDTA).


Ethylenediaminetetraacetic Acid (EDTA) has a claw-like molecular structure that binds to heavy metals and other toxins.
Ethylenediaminetetraacetic Acid (EDTA) after its own abbreviation, is an aminopolycarboxylic acid with the formula [CH2N(CH2CO2H)2]2.
This white, water-insoluble solid, Ethylenediaminetetraacetic Acid (EDTA), is widely used to bind to iron (Fe2+/Fe3+) and calcium ions (Ca2+), forming water-soluble complexes even at neutral pH.


Ethylenediaminetetraacetic Acid (EDTA) is a Lead Chelator and Anti-coagulant.
The mechanism of action of Ethylenediaminetetraacetic Acid (EDTA) is as a Lead Chelating Activity and Calcium Chelating Activity.
The physiologic effect of Ethylenediaminetetraacetic Acid (EDTA) is by means of Decreased Coagulation Factor Activity.


Ethylenediaminetetraacetic Acid (EDTA) is a natural product found in Perilla frutescens, Apis cerana, and other organisms with data available.
Ethylenediaminetetraacetic Acid (EDTA) is a white odourless, colourless crystalline powder, with a melting point of 240C at which it decomposes.
Ethylenediaminetetraacetic Acid (EDTA) is insoluble in cold water, alcohol and general organic solvents, slightly soluble in water, soluble in sodium hydroxide, sodium carbonate and ammonia solution, soluble in boiling water.


The alkali metal salts are soluble in water.
Ethylenediaminetetraacetic Acid (EDTA) is an important complexing agent.
Ethylenediaminetetraacetic Acid (EDTA) is an organic compound with the chemical formula C10H16N2O8 and is a white powder under normal temperature and pressure.


Ethylenediaminetetraacetic Acid (EDTA) is a chelating agent that can bind with Mg2+, Ca2+, Mn2+, Fe2+ and other divalent metal ions.
Mg2+ is often used as an inhibitor of nucleases and proteases because most nucleases and some proteases require Mg2+.
Ethylenediaminetetraacetic Acid (EDTA) is also known to inhibit a range of metallopeptidases, the method of inhibition occurs via the chelation of the metal ion required for catalytic activity.


Ethylenediaminetetraacetic Acid (EDTA) can also be used to test for bioavailability of heavy metals in sediments.
Ethylenediaminetetraacetic Acid (EDTA), Disodium Salt, Dihydrate (Na2EDTA•2H2O), is a chelator of divalent metal cations.
Ethylenediaminetetraacetic Acid (EDTA) is suitable for biochemistry or molecular biology applications.


Ethylenediaminetetraacetic Acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium).
Ethylenediaminetetraacetic Acid (EDTA) has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities.
Ethylenediaminetetraacetic Acid (EDTA) is a common chelating agent, which means it binds strongly to metal ions to form stable, water-soluble compounds.
This function lends itself to widespread applications.



USES and APPLICATIONS of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) is used in the following products: fertilisers and pH regulators and water treatment products.
Release to the environment of Ethylenediaminetetraacetic Acid (EDTA) can occur from industrial use: formulation of mixtures and formulation in materials.
Ethylenediaminetetraacetic Acid (EDTA) is used in the following products: pH regulators and water treatment products.


Ethylenediaminetetraacetic Acid (EDTA) is used in the following areas: mining, scientific research and development and health services.
Ethylenediaminetetraacetic Acid (EDTA) is used for the manufacture of: and chemicals.
Ethylenediaminetetraacetic Acid (EDTA) is also used as an anticoagulant for blood specimens and is applied as a treatment of lead poisoning.


Release to the environment of Ethylenediaminetetraacetic Acid (EDTA) can occur from industrial use: as processing aid, in processing aids at industrial sites, in the production of articles and of substances in closed systems with minimal release.
Ethylenediaminetetraacetic Acid (EDTA) is used in the following products: fertilisers.


Other release to the environment of Ethylenediaminetetraacetic Acid (EDTA) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Release to the environment of Ethylenediaminetetraacetic Acid (EDTA) can occur from industrial use: manufacturing of the substance and formulation of mixtures.
Ethylenediaminetetraacetic Acid (EDTA) is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Ethylenediaminetetraacetic Acid (EDTA) is used in the following products: washing & cleaning products, coating products, polishes and waxes, biocides (e.g. disinfectants, pest control products), adhesives and sealants, fillers, putties, plasters, modelling clay, non-metal-surface treatment products, photo-chemicals, air care products, metal surface treatment products and textile treatment products and dyes.


Other release to the environment of Ethylenediaminetetraacetic Acid (EDTA) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints) and outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).


Other release to the environment of Ethylenediaminetetraacetic Acid (EDTA) is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).


Ethylenediaminetetraacetic Acid (EDTA) can be found in complex articles, with no release intended: vehicles, machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and electrical batteries and accumulators.
Ethylenediaminetetraacetic Acid (EDTA) is intended to be released from: packaging material for metal parts (releasing grease/corrosion inhibitors).


Ethylenediaminetetraacetic Acid (EDTA) can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture), metal (e.g. cutlery, pots, toys, jewellery), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), rubber (e.g. tyres, shoes, toys), wood (e.g. floors, furniture, toys) and plastic (e.g. food packaging and storage, toys, mobile phones). Ethylenediaminetetraacetic Acid (EDTA) is intended to be released from scented: clothes, eraser, toys, paper products and CDs.


Ethylenediaminetetraacetic Acid (EDTA) is used in the following areas: agriculture, forestry and fishing and formulation of mixtures and/or re-packaging.
Release to the environment of Ethylenediaminetetraacetic Acid (EDTA) can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid, and of substances in closed systems with minimal release.


Other release to the environment of Ethylenediaminetetraacetic Acid (EDTA) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Ethylenediaminetetraacetic Acid (EDTA) is a chelating agent (chelating agents) that sequesters a variety of polyvalent cations.
Ethylenediaminetetraacetic Acid (EDTA) is used in pharmaceutical manufacturing and as a food additive.
Ethylenediaminetetraacetic Acid (EDTA) is the acid form of edetate, a chelating agent with anti-hypercalcemic and anticoagulant properties.


Ethylenediaminetetraacetic Acid (EDTA) binds calcium and heavy metal ions, forming soluble stable complexes which are readily excreted by the kidneys.
This results in a decrease in serum calcium levels.
Ethylenediaminetetraacetic Acid (EDTA) is also used as an anticoagulant for blood specimens and is applied as a treatment of lead poisoning.


Chelation therapy is a treatment that involves repeated intravenous (IV) administration of a chemical solution of Ethylenediaminetetraacetic Acid (EDTA).
Ethylenediaminetetraacetic Acid (EDTA) is used to treat acute and chronic lead poisoning by pulling toxins (including heavy metals such as lead, cadmium, and mercury) from the bloodstream.


The word "chelate" comes from the Greek root chele, which means "to claw."
The U.S. Food and Drug Administration (FDA) approved Ethylenediaminetetraacetic Acid (EDTA) chelation therapy as a treatment for lead and heavy metal poisoning.


Ethylenediaminetetraacetic Acid (EDTA) is also used as an emergency treatment for hypercalcemia (excessive calcium levels) and the control of ventricular arrhythmias (abnormal heart rhythms) associated with digitalis toxicity.
Ethylenediaminetetraacetic Acid (EDTA) is a medication used in the management and treatment of heavy metal toxicity.


Ethylenediaminetetraacetic Acid (EDTA) is in the chelating class of drugs.
Ethylenediaminetetraacetic Acid (EDTA) is used textiles and paper.
In industry, Ethylenediaminetetraacetic Acid (EDTA) is mainly used to sequester (bind or confine) metal ions in aqueous solution.


In the textile industry, Ethylenediaminetetraacetic Acid (EDTA) prevents metal ion impurities from modifying colours of dyed products.
In the pulp and paper industry, Ethylenediaminetetraacetic Acid (EDTA) inhibits the ability of metal ions, especially Mn2+, from catalysing the disproportionation of hydrogen peroxide, which is used in chlorine-free bleaching.


Food: In a similar manner, Ethylenediaminetetraacetic Acid (EDTA) is added to some food as a preservative or stabiliser to prevent catalytic oxidative decolouration, which is catalysed by metal ions.
Ethylenediaminetetraacetic Acid (EDTA) is used lead poisoning and heavy metal toxicity.


Chelation therapy using Ethylenediaminetetraacetic Acid (EDTA) is the medically-accepted treatment for lead poisoning.
Injected intravenously and once in the bloodstream, Ethylenediaminetetraacetic Acid (EDTA) traps lead and other metals, forming a compound that the body can eliminate in the urine.


The process generally takes 1 to 3 hours.
Other heavy metal poisonings treated with chelation include mercury, arsenic, aluminum, chromium, cobalt, manganese, nickel, selenium, zinc, tin, and thallium.


Chelating agents other than Ethylenediaminetetraacetic Acid (EDTA) are also used to clear several of these substances from the bloodstream.
Ethylenediaminetetraacetic Acid (EDTA) is thus used to dissolve Fe- and Ca-containing scale as well as to deliver iron ions under conditions where its oxides are insoluble.


Ethylenediaminetetraacetic Acid (EDTA) is available as several salts, notably disodium EDTA, sodium calcium edetate, and tetrasodium EDTA, but these all function similarly.
Eyedrops: Ethylenediaminetetraacetic Acid (EDTA) serves as a preservative (usually to enhance the action of another preservative such as benzalkonium chloride or thiomersal) in ocular preparations and eyedrops.


Cosmetics: In shampoos, cleaners, and other personal care products, Ethylenediaminetetraacetic Acid (EDTA) salts are used as a sequestering agent to improve their stability in air.
Ethylenediaminetetraacetic Acid (EDTA) is widely used, can be used for processing colour photographic materials bleach fixing bath washing, dyeing auxiliaries, textile processing auxiliaries, detergent, stabiliser, synthetic rubber and polymerization initiator.


Ethylenediaminetetraacetic Acid (EDTA) is used Agricultural Formulations, Bleaching (Pulp), Cleaning (Hard Surface), Cleaning (Industrial), Cleaning (Institutional), Cleaning (Metal), Cleaning (Offshore), Drilling/Completion Fluids,
Industrial Cleaning, Offshore Cleaning, Oilfield, Photography, and Textile.


Ethylenediaminetetraacetic Acid (EDTA) is predominantly used in agriculture, water treatment, pulp and paper industries and also used in the manufacture of cleaners and detergents
Ethylenediaminetetraacetic Acid (EDTA) is used chelating agents bind or capture trace amounts of iron, copper, manganese, calcium and other metals that occur naturally in many materials.


Such naturally occurring metals can cause chemical degradation, discoloration, scaling, instability, rancidity, ineffective cleaning performance and other problems.
In Metalworking industries Ethylenediaminetetraacetic Acid (EDTA) is used for surface preparation, metal cleaning, metal plating, and in metalworking fluids.


In Cleaning products, Ethylenediaminetetraacetic Acid (EDTA) is employed to remove hard water scale, soap film, and inorganic scales.
Ethylenediaminetetraacetic Acid (EDTA) is commonly used in a wide variety of cleaning products and formulations, including hard surface cleaners, laundry detergents, bactericidal cleaners, vehicle washes etc.


Ethylenediaminetetraacetic Acid (EDTA) finds many specialised uses in the biomedical labs, such as in veterinary ophthalmology as an anticollagenase to prevent the worsening of corneal ulcers in animals.
In tissue culture Ethylenediaminetetraacetic Acid (EDTA) is used as a chelating agent that binds to calcium and prevents joining of cadherins between cells, preventing clumping of cells grown in liquid suspension, or detaching adherent cells for passaging.


In histopathology, Ethylenediaminetetraacetic Acid (EDTA) can be used as a decalcifying agent making it possible to cut sections using a microtome once the tissue sample is demineralised.
Ethylenediaminetetraacetic Acid (EDTA) is also used to remove crud (corroded metals) from fuel rods in nuclear reactors.


Ethylenediaminetetraacetic acid (EDTA) is a substituted diamine widely used in domestic and industrial applications.
Ethylenediaminetetraacetic Acid (EDTA) chelate metal divalent cations, such as calcium, magnesium, zinc, copper, and manganese, to form metal-EDTA complexes.


Ethylenediaminetetraacetic Acid (EDTA) is suitable for cleaning products and detergent formulations.
In the paper and pulp industry, Ethylenediaminetetraacetic Acid (EDTA) reduces the adverse effects of metal ions on bleaching.
As an antibacterial agent, Ethylenediaminetetraacetic Acid (EDTA) can remove calcium and magnesium divalent cations in the outer membrane and cause the loss of membrane lipopolysaccharide, making bacteria sensitive to bactericides.


Free Ethylenediaminetetraacetic Acid (EDTA) has an adverse effect on mammalian reproduction and development.
Ethylenediaminetetraacetic Acid (EDTA) can sequester ions in sediments that cause atherosclerosis, cancer and heart disease.
Ethylenediaminetetraacetic Acid (EDTA) reduces free radical reactions and oxidation processes, which helps to overcome cell membrane damage.


Ethylenediaminetetraacetic Acid (EDTA) can bind to calcium and reduce the risk of developing hypercalcemia in cancer patients.
The transmembrane Ethylenediaminetetraacetic Acid (EDTA) gradient method facilitates drug delivery, thereby enhancing drug retention and therapeutic effects and reducing levels of cytotoxicity.


Ethylenediaminetetraacetic Acid (EDTA) has a wide range of uses.
Ethylenediaminetetraacetic Acid (EDTA) can be used as bleaching fixative solution for color sensitive material washing processing, dyeing aid, fiber treatment aid, cosmetic additive, blood anticoagulant, detergent, stabilizer and synthetic rubber polymerization initiator.


Ethylenediaminetetraacetic Acid (EDTA) can form stable water-soluble complexes with alkaline earth metals, rare earth elements and transition metals.
In addition to sodium, there are ammonium salts and various salts of iron, magnesium, calcium, copper, manganese, zinc, cobalt and aluminum, all of which have different uses.


In addition, Ethylenediaminetetraacetic Acid (EDTA) can also be used to enable the rapid excretion of harmful radioactive metals from the body to play a detoxification role.
Ethylenediaminetetraacetic Acid (EDTA)'s also a water treatment agent.


Ethylenediaminetetraacetic Acid (EDTA) is also an important indicator, but it is used for titrating metals such as nickel and copper.
When used, Ethylenediaminetetraacetic Acid (EDTA) should be used together with ammonia to play the role of indicator.
Ethylenediaminetetraacetic Acid (EDTA) is used for in vitro anticoagulation of blood.


Ethylenediaminetetraacetic Acid (EDTA) is an anticoagulant additive for clinical blood testing.
Ethylenediaminetetraacetic Acid (EDTA) is used for pretreatment (anticoagulation) of blood samples during clinical blood collection and testing.
Ethylenediaminetetraacetic Acid (EDTA) is high solubility and fast anticoagulation.


Ethylenediaminetetraacetic Acid (EDTA) is mainly used to bind metal ions in aqueous solution making EDTA useful in a wide variety of uses as a chelating agent.
Ethylenediaminetetraacetic Acid (EDTA) is widely used to dissolve limescale.


In shampoos, cleaners, and other personal care products Ethylenediaminetetraacetic Acid (EDTA) salts are used as stabilizers.
Ethylenediaminetetraacetic Acid (EDTA) is added to some food as a preservative or stabilizer to prevent catalytic oxidative decoloration, which is catalyzed by metal ions.


In the pulp and paper industry, Ethylenediaminetetraacetic Acid (EDTA) inhibits the ability of metal ions, especially Mn2+, from catalyzing the disproportionation of hydrogen peroxide, which is used in "chlorine-free bleaching."
Ethylenediaminetetraacetic Acid (EDTA) decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification.


Ethylenediaminetetraacetic Acid (EDTA) can alleviate the liver fibrosis.
Ethylenediaminetetraacetic Acid (EDTA) can be used for coronary artery disease and neural system disease research.
Ethylenediaminetetraacetic Acid (EDTA) can also be used to remove the inhibition of heavy metal ions on enzymes.


Chelating agent, Ethylenediaminetetraacetic Acid (EDTA) is used in many enzyme buffers and at higher concentrations, as enzyme inactivator
Detergent uses of Ethylenediaminetetraacetic Acid (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) can be used as a labeling buffer component for washing during cell lysis {155}.


Supplements: Ethylenediaminetetraacetic Acid (EDTA) is used as a supplement for synthetic tubal fluid culture 1 (SOFC1) medium for embryo culture.
Ethylenediaminetetraacetic Acid (EDTA) is used as a complexing agent for many cations.
Ethylenediaminetetraacetic Acid (EDTA) prevents metal ion impurities and used to remove excess iron from the body.


Ethylenediaminetetraacetic Acid (EDTA) acts as a sequestering agent in cosmetic products.
Ethylenediaminetetraacetic Acid (EDTA) is used as a complexing agent for many cations.
Ethylenediaminetetraacetic Acid (EDTA) prevents metal ion impurities and used to remove excess iron from the body.


Ethylenediaminetetraacetic Acid (EDTA) acts as a sequestering agent in cosmetic products.
For example, Ethylenediaminetetraacetic Acid (EDTA) may be added as a stabilizer to foods or cosmetic products in order to sequester metal ions that would otherwise act as catalysts towards the production of harmful or undesirable products (e.g. discoloration, carcinogens).


In other cases, Ethylenediaminetetraacetic Acid (EDTA) can improve the solubility of otherwise insoluble metals; for example, in agricultural applications, EDTA can improve iron bioavailability to plants.
Ethylenediaminetetraacetic Acid (EDTA) has also been used for chelation therapy, to treat heavy metal poisoning.


Ethylenediaminetetraacetic Acid (EDTA) products are used for hair, skin, chelation, endodontics, in food, in skincare, shampoo and dentistry.
Ethylenediaminetetraacetic Acid (EDTA) is a representative chelating agent.
Ethylenediaminetetraacetic Acid (EDTA) is an important complexing agent.


-Cell sorting analysis uses of Ethylenediaminetetraacetic Acid (EDTA):
Firstly, Ethylenediaminetetraacetic Acid (EDTA) is used single-cell suspension of spleen dendritic cells for magnetic bead cell sorting.
Secondly, incubate EpCAM + cells and FITC-labeled antibodies for cell sorting analysis.


-The applications of Ethylenediaminetetraacetic acid (EDTA) have been reported as following:
Complexing agent uses of Ethylenediaminetetraacetic Acid (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) is a hydrophilic gold chelator that converts metal ions into inactive, cyclized metal complexes.
Therefore, Ethylenediaminetetraacetic Acid (EDTA) can be used in industry to solve metal pollutants.


-Blood anticoagulant uses of Ethylenediaminetetraacetic Acid (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) cannot be absorbed by the gastrointestinal tract.
Intravenous injection of sodium EDTA causes hypocalcemic hand-foot twitching.

Ethylenediaminetetraacetic Acid (EDTA) is commonly used for plasma or molecular diagnostics, and calcium chelation.
Ethylenediaminetetraacetic Acid (EDTA) can be used as an anticoagulant in blood cell count and cell morphology analysis.


-Other key applications for Ethylenediaminetetraacetic Acid (EDTA) include:
*In Photography as a bleach in photographic film processing.
*In the manufacturing of paper to maximize bleaching efficiency during pulping, prevent brightness reversion, and protect bleach potency.
*In Scale removal and prevention - to clean calcium and other types of scale from boilers, evaporators, heat exchangers, filter cloths, and glass-lined kettles.
*Water treatment - to control water hardness and scale-forming calcium and magnesium ions and to prevent scale formation.


-Laboratory applications of Ethylenediaminetetraacetic Acid (EDTA):
In the laboratory, Ethylenediaminetetraacetic Acid (EDTA) is widely used for scavenging metal ions: In biochemistry and molecular biology, ion depletion is commonly used to deactivate metal-dependent enzymes, either as an assay for their reactivity or to suppress damage to DNA, proteins, and polysaccharides.

Ethylenediaminetetraacetic Acid (EDTA) also acts as a selective inhibitor against dNTP hydrolyzing enzymes (Taq polymerase, dUTPase, MutT), liver arginase and horseradish peroxidase independently of metal ion chelation.

These findings urge the rethinking of the utilisation of Ethylenediaminetetraacetic Acid (EDTA) as a biochemically inactive metal ion scavenger in enzymatic experiments.

In analytical chemistry, Ethylenediaminetetraacetic Acid (EDTA) is used in complexometric titrations and analysis of water hardness or as a masking agent to sequester metal ions that would interfere with the analyses.


-Water softener uses of Ethylenediaminetetraacetic Acid (EDTA):
The reduction of water hardness in laundry applications and the dissolution of scale in boilers both rely on Ethylenediaminetetraacetic Acid (EDTA) and related complexants to bind Ca2+, Mg2+, as well as other metal ions.

Once bound to Ethylenediaminetetraacetic Acid (EDTA), these metal complexes are less likely to form precipitates or to interfere with the action of the soaps and detergents.
For similar reasons, cleaning solutions often contain Ethylenediaminetetraacetic Acid (EDTA).

In a similar manner Ethylenediaminetetraacetic Acid (EDTA) is used in the cement industry for the determination of free lime and free magnesia in cement and clinkers.
The solubilisation of Fe3+ ions at or below near neutral pH can be accomplished using Ethylenediaminetetraacetic Acid (EDTA).

This property is useful in agriculture including hydroponics. However, given the pH dependence of ligand formation, Ethylenediaminetetraacetic Acid (EDTA) is not helpful for improving iron solubility in above neutral soils.
Otherwise, at near-neutral pH and above, iron(III) forms insoluble salts, which are less bioavailable to susceptible plant species.


-Scrubbing uses of Ethylenediaminetetraacetic Acid (EDTA):
Aqueous [Fe(EDTA)]− is used for removing ("scrubbing") hydrogen sulfide from gas streams.
This conversion is achieved by oxidising the hydrogen sulfide to elemental sulfur, which is non-volatile:
2 [Fe(EDTA)]− + H2S → 2 [Fe(EDTA)]2− + S + 2 H+

In this application, the iron(III) centre is reduced to its iron(II) derivative, which can then be reoxidised by air.
In similar manner, nitrogen oxides are removed from gas streams using [Fe(EDTA)]2−.
The oxidising properties of [Fe(EDTA)]− are also exploited in photography, where it is used to solubilise silver particles.


-Analysis uses of Ethylenediaminetetraacetic Acid (EDTA):
In medical diagnosis and organ function tests (here, kidney function test), the chromium(III) complex [Cr(EDTA)]− (as radioactive chromium-51 (51Cr)) is administered intravenously and its filtration into the urine is monitored.

This method is useful for evaluating glomerular filtration rate (GFR) in nuclear medicine.
Ethylenediaminetetraacetic Acid (EDTA) is used extensively in the analysis of blood.
Ethylenediaminetetraacetic Acid (EDTA) is an anticoagulant for blood samples for CBC/FBCs, where the EDTA chelates the calcium present in the blood specimen, arresting the coagulation process and preserving blood cell morphology.

Tubes containing Ethylenediaminetetraacetic Acid (EDTA) are marked with lavender (purple) or pink tops.
Ethylenediaminetetraacetic Acid (EDTA) is also in tan top tubes for lead testing and can be used in royal blue top tubes for trace metal testing.
Ethylenediaminetetraacetic Acid (EDTA) is a slime dispersant, and has been found to be highly effective in reducing bacterial growth during implantation of intraocular lenses (IOLs).


-Alternative medicine uses of Ethylenediaminetetraacetic Acid (EDTA):
Some alternative practitioners believe Ethylenediaminetetraacetic Acid (EDTA) acts as an antioxidant, preventing free radicals from injuring blood vessel walls, therefore reducing atherosclerosis.
These ideas are unsupported by scientific studies, and seem to contradict some currently accepted principles.
The U.S. FDA has not approved it for the treatment of atherosclerosis.


-Ion-exchange chromatography uses of Ethylenediaminetetraacetic Acid (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) was used in separation of the lanthanide metals by ion-exchange chromatography.
Perfected by F. H. Spedding et al. in 1954, the method relies on the steady increase in stability constant of the lanthanide Ethylenediaminetetraacetic Acid (EDTA) complexes with atomic number.

Using sulfonated polystyrene beads and Cu2+ as a retaining ion, Ethylenediaminetetraacetic Acid (EDTA) causes the lanthanides to migrate down the column of resin while separating into bands of pure lanthanides.
The lanthanides elute in order of decreasing atomic number.

Due to the expense of this method, relative to countercurrent solvent extraction, ion exchange is now used only to obtain the highest purities of lanthanides (typically greater than 99.99%).


-Medicine uses of Ethylenediaminetetraacetic Acid (EDTA):
Sodium calcium edetate, an Ethylenediaminetetraacetic Acid (EDTA) derivative, is used to bind metal ions in the practice of chelation therapy, such as for treating mercury and lead poisoning.

Ethylenediaminetetraacetic Acid (EDTA) is used in a similar manner to remove excess iron from the body.
This therapy is used to treat the complication of repeated blood transfusions, as would be applied to treat thalassaemia.


-Dentistry uses of Ethylenediaminetetraacetic Acid (EDTA):
Dentists and endodontists use Ethylenediaminetetraacetic Acid (EDTA) solutions to remove inorganic debris (smear layer) and lubricate the root canals in endodontics.

This procedure helps prepare root canals for obturation.
Furthermore, Ethylenediaminetetraacetic Acid (EDTA) solutions with the addition of a surfactant loosen up calcifications inside a root canal and allow instrumentation (canal shaping) and facilitate apical advancement of a file in a tight or calcified root canal towards the apex.



PHYSICAL PROPERTIES OF ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
The chemical names of ethylenediaminetetraacetic acid include Ethylenediamine tetraacetic acid, (Ethylenedinitrilo) tetraacetic acid, Edetic acid and EDTA.
EDTA is white powder, which is soluble in sodium hydroxide, sodium carbonate and ammonia solution, and 160 parts of boiling water, and slightly soluble in cold water, insoluble in ethanol and general organic solvents.
It can form extremely stable water-soluble complexes with alkali metals, rare earth elements and transition metals.
EDTA decompose above its melting point 240°C.



SOLUBILITY OF ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) is soluble in sodium hydroxide, sodium carbonate, ammonia solution, acid and common organic solvents.
Ethylenediaminetetraacetic Acid (EDTA) is slightly soluble in water.



PHYSICAL AND CHEMICAL PROPERTIES OF ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) is used white odorless, tasteless, colorless crystalline powder, melting point 250℃ (decomposition).
Ethylenediaminetetraacetic Acid (EDTA) is insoluble in ethanol and general organic solvents, slightly soluble in cold water, soluble in aqueous solutions of sodium hydroxide, sodium carbonate and ammonia.

Ethylenediaminetetraacetic Acid (EDTA) can dissolve in more than 5% of inorganic acid, can also dissolve in ammonia and 160 parts of boiling water.
Ethylenediaminetetraacetic Acid (EDTA)'s alkali metal salts are soluble in water.



MOLARITY OF ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
Molarity is best used in expressing Ethylenediaminetetraacetic Acid (EDTA) concentration, because the reaction involves the complexation of one metal ion by one EDTA molecule or ion, whether the free acid form of EDTA or one of its more soluble Sodium salts is used.
The general reaction involving the Disodium salt is:

EDTA2- + Mn+ → [EDTA-M]+n-2
where M = Ca, Mg, Cd, Mn, Ni, Al, Zn, Bi, Co, Cu, or other metal ion

An indicator is added that forms a colored complex with some of the metal ion being determined.
When the endpoint is reached, all of the free metal ion has been complexed by the Ethylenediaminetetraacetic Acid (EDTA).
The last addition of Ethylenediaminetetraacetic Acid (EDTA) then removes the metal ion from its complex with the indicator, producing a color change.

The relative strength of the Ethylenediaminetetraacetic Acid (EDTA)-metal ion complex compared to that of the indicator-metal ion complex determines whether a direct titration or a back-titration is applicable.

Ethylenediaminetetraacetic Acid (EDTA) is most commonly used to determine hardness (i.e., Calcium and Magnesium ions) in water, where the pH must be approximately 10 and is usually controlled by adding a buffer such as Water Hardness Buffer.

Water Hardness Indicator (Eriochrome Black T), Eriochrome Blue Black R, Calmagite, and Murexide are used for hardness or Calcium determinations using Ethylenediaminetetraacetic Acid (EDTA).



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
CAS Number: 60-00-4
Molecular Weight: 292.24
Beilstein: 1716295
EC Number: 200-449-4
MDL Number: MFCD00003541
Physical State: Powder
Color: White
Odor: Odorless
Melting Point/Freezing Point: Melting point/range: 250 °C - dec.
Initial Boiling Point and Boiling Range: No data available
Flammability (solid, gas): No data available
Upper/Lower Flammability or Explosive Limits: No data available
Flash Point: Not applicable
Autoignition Temperature: No data available
Decomposition Temperature: > 220 °C

pH: 2.5 at 10 g/l at 23 °C
Viscosity:
Kinematic Viscosity: No data available
Dynamic Viscosity: No data available
Water Solubility: 0.4 g/l at 20 °C
Partition Coefficient (n-octanol/water): No data available
Vapor Pressure: No data available
Density: 1.46 g/cm³ at 20 °C
Relative Density: No data available
Relative Vapor Density: No data available
Particle Characteristics: No data available
Explosive Properties: No data available
Oxidizing Properties: None
Other Safety Information:
Dissociation constant: 8.85 - 10.44 at 20 °C
Molecular Weight: 292.24 g/mol

XLogP3-AA: -5.9
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 10
Rotatable Bond Count: 11
Exact Mass: 292.09066547 g/mol
Monoisotopic Mass: 292.09066547 g/mol
Topological Polar Surface Area: 156 Ų
Heavy Atom Count: 20
Formal Charge: 0
Complexity: 316
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1

Compound Is Canonicalized: Yes
CAS No. 60-00-4
EC No. 200-449-4
Formula: (HO2CCH2)2NCH­2CH2N(CH2CO2H)2
Molecular weight: 292.24
Appearance: white crystalline solid.
Relative density: 0.86 g/cm3
Melting Point: 220C (428F)
Solubility: Very slightly soluble in cold water.
pH (1%): 2.5
Chemical Formula: C10H16N2O8
Molar Mass: 292.244 g·mol⁻¹
Appearance: Colorless crystals
Density: 0.860 g cm⁻³ (at 20 °C)
Log P: -0.836
Acidity (pKa): 2.0, 2.7, 6.16, 10.26

Thermochemistry:
Standard Enthalpy of Formation (ΔfH⦵298): -1765.4 to -1758.0 kJ mol⁻¹
Standard Enthalpy of Combustion (ΔcH⦵298): -4461.7 to -4454.5 kJ mol⁻¹
CAS Number: 65501-24-8
Packing: 500g/bottle
Appearance: White crystal powder
Chemical Properties: Odorless, soluble in water, easy to absorb moisture
Molecular Weight: 442.56
pH Value: 7.3±1 (5% aqueous solution, g/ml)
Solubility in Water: ≥60% (g/ml, 25℃)
Validity Period: 3 years
Storage Conditions: Dry and sealed at room temperature.



FIRST AID MEASURES of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P2
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available


ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT

Ethylenediaminetetraacetic acid disodium salt, often abbreviated as Ethylenediaminetetraacetic acid disodium salt, is a chemical compound with the molecular formula C10H14N2Na2O8.
Ethylenediaminetetraacetic acid disodium salt is a synthetic organic compound derived from ethylenediamine and acetic acid.
Ethylenediaminetetraacetic acid disodium salt is a chelating agent, which means it can form stable complexes with metal ions by coordinating with their positively charged ions.

CAS Number: 6381-92-6
EC Number: 205-358-3



APPLICATIONS


Ethylenediaminetetraacetic acid disodium salt (Ethylenediaminetetraacetic acid disodium salt) is widely used in the field of analytical chemistry.
In analytical chemistry, Ethylenediaminetetraacetic acid disodium salt serves as a chelating agent to determine metal ion concentrations through complexometric titrations.
Ethylenediaminetetraacetic acid disodium salt is used to sequester and remove metal ions from water in various industrial and laboratory applications.

In the food and beverage industry, Ethylenediaminetetraacetic acid disodium salt is utilized as a food additive (E385) to preserve the color and flavor of processed foods.
Ethylenediaminetetraacetic acid disodium salt prevents the oxidation of food components by binding to metal ions that catalyze oxidation reactions.
Ethylenediaminetetraacetic acid disodium salt is employed in pharmaceuticals as a stabilizing agent and preservative in some medications.

In the cosmetics and personal care industry, it serves as a stabilizer in various products, including creams and lotions.
Medical applications include the use of Ethylenediaminetetraacetic acid disodium salt in chelation therapy to treat heavy metal poisoning.
Ethylenediaminetetraacetic acid disodium salt can effectively bind to heavy metal ions, such as lead and mercury, aiding in their removal from the body.
Ethylenediaminetetraacetic acid disodium salt is used as an anticoagulant in blood collection tubes to prevent clotting and maintain sample integrity.

Ethylenediaminetetraacetic acid disodium salt is a common component in many laboratory reagents and buffers used in molecular biology and biochemistry research.
In the textiles industry, Ethylenediaminetetraacetic acid disodium salt is utilized as a color-removing agent in the dyeing and printing processes.
Ethylenediaminetetraacetic acid disodium salt is employed as a metal ion control agent in pulp and paper manufacturing to improve paper quality.

In the photography industry, Ethylenediaminetetraacetic acid disodium salt is used in photographic development solutions to prevent the formation of unwanted precipitates.
Ethylenediaminetetraacetic acid disodium salt plays a role in soil science, where it is used to chelate metal ions in soil samples for analysis.
In the oil and gas industry, it helps prevent scale formation by sequestering metal ions that can cause scaling in pipelines and equipment.

Ethylenediaminetetraacetic acid disodium salt is a key ingredient in some household cleaning products, contributing to their efficacy in removing mineral deposits.
In the electronics industry, it is used as a cleaning agent to remove metal ion contaminants from semiconductor surfaces.

Ethylenediaminetetraacetic acid disodium salt is added to some shampoos and personal care products to improve product stability and shelf life.
Ethylenediaminetetraacetic acid disodium salt is used in the manufacture of detergents to enhance their performance by binding to metal ions that interfere with cleaning.
Ethylenediaminetetraacetic acid disodium salt is employed in water treatment plants to reduce the effects of hard water and prevent scale buildup in pipes.

Ethylenediaminetetraacetic acid disodium salt is used in the preservation of archaeological and historical artifacts to prevent metal corrosion.
In the agricultural industry, it can be used to correct nutrient deficiencies in plants by chelating essential metals.
Ethylenediaminetetraacetic acid disodium salt is employed in the development of nanomaterials and nanoparticles for various applications.

Ethylenediaminetetraacetic acid disodium salt is commonly used in the pharmaceutical industry to improve the stability of certain medications.
In the textile industry, Ethylenediaminetetraacetic acid disodium salt serves as a color-removing agent and as a component in dyeing processes.
Ethylenediaminetetraacetic acid disodium salt finds application in the manufacture of soaps and detergents to enhance their cleaning efficiency.

In the cosmetics and personal care sector, it is utilized to maintain product stability and prevent rancidity.
Ethylenediaminetetraacetic acid disodium salt is employed in the preservation of art and historical artifacts to prevent metal corrosion.
In the oil drilling industry, it is added to drilling fluids to control the adverse effects of metal ions.

Ethylenediaminetetraacetic acid disodium salt plays a role in water treatment by sequestering metal ions that can cause scale buildup.
In the field of molecular biology, Ethylenediaminetetraacetic acid disodium salt is used as an essential component in DNA and RNA extraction.

Ethylenediaminetetraacetic acid disodium salt contributes to the formulation of hemodialysis solutions to remove excess metals from the blood.
Ethylenediaminetetraacetic acid disodium salt is added to anticoagulant solutions used in blood collection tubes to maintain sample quality.

Ethylenediaminetetraacetic acid disodium salt helps improve the stability of certain photographic chemicals and prevents precipitation.
In the automotive industry, it is used as an ingredient in automotive cooling systems to inhibit corrosion.

Ethylenediaminetetraacetic acid disodium salt can be found in some eye drops and ointments, contributing to their preservation.
Ethylenediaminetetraacetic acid disodium salt is employed in the electronics industry for cleaning and descaling semiconductor surfaces.
Ethylenediaminetetraacetic acid disodium salt is utilized in the production of specialty chemicals, including catalysts and reagents.

In the mining and mineral processing industry, it is added to flotation reagents for ore separation.
Ethylenediaminetetraacetic acid disodium salt is used in the manufacture of cleaning agents for removing mineral deposits.

In the agriculture sector, it may be employed as a micronutrient fertilizer.
Ethylenediaminetetraacetic acid disodium salt plays a role in the formulation of certain veterinary medications.
In the construction industry, it is used to improve the workability of cement and concrete mixtures.

Ethylenediaminetetraacetic acid disodium salt is used in the preservation of samples in laboratories and research settings.
Ethylenediaminetetraacetic acid disodium salt contributes to the stability of certain chemical solutions used in analytical chemistry.
In the food and beverage industry, it is employed as a sequestrant to enhance the quality of processed foods.

Ethylenediaminetetraacetic acid disodium salt is sometimes added to swimming pool water to control metal ion content and prevent staining.
Ethylenediaminetetraacetic acid disodium salt serves as a valuable tool in environmental chemistry for the analysis of metal ion concentrations in natural water sources.

In the pharmaceutical industry, Ethylenediaminetetraacetic acid disodium salt is used to enhance the stability of certain medications and prevent degradation caused by metal ions.
Ethylenediaminetetraacetic acid disodium salt plays a crucial role in analytical chemistry, particularly in complexometric titrations to determine metal ion concentrations in samples.
Ethylenediaminetetraacetic acid disodium salt is employed in the food and beverage industry as a food additive (E385) to maintain product color and flavor.
Ethylenediaminetetraacetic acid disodium salt is added to canned and packaged foods to prevent the deterioration of food quality due to metal-induced oxidation reactions.

Ethylenediaminetetraacetic acid disodium salt is utilized in the cosmetics and personal care industry to stabilize and extend the shelf life of various products.
In medical applications, Ethylenediaminetetraacetic acid disodium salt is used as an anticoagulant in blood collection tubes to ensure the integrity of blood samples.
Ethylenediaminetetraacetic acid disodium salt is a vital component in chelation therapy, a medical treatment for heavy metal poisoning, where it binds to and facilitates the removal of toxic metal ions from the body.
Ethylenediaminetetraacetic acid disodium salt is applied in the preservation of historical artifacts and artworks to prevent corrosion and degradation.
In the oil and gas industry, Ethylenediaminetetraacetic acid disodium salt is used to prevent scale formation by sequestering metal ions that can cause scaling in pipelines and equipment.

Ethylenediaminetetraacetic acid disodium salt contributes to the removal of metal contaminants from semiconductor surfaces in the electronics industry.
Ethylenediaminetetraacetic acid disodium salt is used in soil science to chelate metal ions in soil samples for analysis.

In the pulp and paper industry, it acts as a metal ion control agent to enhance paper quality and prevent coloration.
Ethylenediaminetetraacetic acid disodium salt plays a role in the development of nanomaterials and nanoparticles for various applications.
Ethylenediaminetetraacetic acid disodium salt is used as a cleaning agent in the electronics industry to remove metal ion contaminants from circuit boards.

Ethylenediaminetetraacetic acid disodium salt is employed in the mining industry as a flotation reagent to assist in ore separation.
In the automotive sector, it is added to automotive cooling systems to prevent corrosion and scale formation.
Ethylenediaminetetraacetic acid disodium salt is an essential component in laboratory reagents and buffers used in molecular biology and biochemistry research.
Ethylenediaminetetraacetic acid disodium salt finds application in water treatment plants to reduce the effects of hard water and prevent scale buildup in pipes.

Ethylenediaminetetraacetic acid disodium salt is used as a component in some household cleaning products to improve their effectiveness in removing mineral deposits.
In photography, it helps maintain the stability of photographic development solutions by preventing precipitation.
Ethylenediaminetetraacetic acid disodium salt is added to some shampoos and personal care products to improve product stability and shelf life.

Ethylenediaminetetraacetic acid disodium salt is employed in the textile industry to remove metal ions and enhance the dyeing process.
Ethylenediaminetetraacetic acid disodium salt is utilized in agriculture as a chelated micronutrient fertilizer.
In the construction industry, it improves the workability of cement and concrete mixtures.
Ethylenediaminetetraacetic acid disodium salt plays a vital role in a wide range of scientific, industrial, and medical applications, thanks to its versatile chelation properties.

In the automotive industry, Ethylenediaminetetraacetic acid disodium salt is added to automotive cooling systems as a corrosion inhibitor to protect engine components from metal-induced corrosion and scale buildup.
Ethylenediaminetetraacetic acid disodium salt is used in the preparation of laboratory reagents and buffers for biochemical and molecular biology research to ensure the accuracy of experiments.
Ethylenediaminetetraacetic acid disodium salt is employed in the mining and metallurgy industry to assist in the separation of valuable minerals from ore by binding to and facilitating the removal of unwanted metal ions.

Ethylenediaminetetraacetic acid disodium salt finds application in the electronics industry for cleaning semiconductor surfaces and preventing metal ion contamination during manufacturing.
In the water treatment field, Ethylenediaminetetraacetic acid disodium salt is utilized to sequester metal ions that can lead to the formation of scale deposits and reduce the efficiency of water systems.
Ethylenediaminetetraacetic acid disodium salt plays a role in the development of nanomaterials and nanoparticles, contributing to advancements in nanotechnology and materials science.

Ethylenediaminetetraacetic acid disodium salt is used in analytical chemistry as a complexing agent to determine the concentration of metal ions in environmental samples, such as water and soil.
Ethylenediaminetetraacetic acid disodium salt is employed in the cosmetics and personal care industry to maintain the stability and quality of various products, including creams, lotions, and shampoos.
In the construction sector, Ethylenediaminetetraacetic acid disodium salt is used to enhance the workability of cement and concrete mixtures, improving their performance and durability.
Ethylenediaminetetraacetic acid disodium salt is a key ingredient in certain veterinary medications, ensuring the safety and effectiveness of these pharmaceutical products.

Ethylenediaminetetraacetic acid disodium salt is used in the oil and gas industry to control the buildup of scale deposits in pipelines and equipment, which can obstruct oil flow.

Ethylenediaminetetraacetic acid disodium salt contributes to the preservation of archaeological artifacts, protecting them from metal corrosion and environmental degradation.
In the pulp and paper industry, it serves as a metal ion control agent to maintain paper quality and prevent discoloration during production.
Ethylenediaminetetraacetic acid disodium salt is utilized in the photography industry to stabilize photographic development solutions, preventing unwanted precipitation.

Ethylenediaminetetraacetic acid disodium salt plays a role in soil remediation efforts by assisting in the removal of heavy metal contaminants from polluted soil.
Ethylenediaminetetraacetic acid disodium salt is added to some cleaning products and detergents to enhance their effectiveness in removing mineral deposits, such as limescale.
In agriculture, Ethylenediaminetetraacetic acid disodium salt is used as a micronutrient fertilizer to deliver essential metals to plants in a form that is readily accessible.

Ethylenediaminetetraacetic acid disodium salt finds application in the food and beverage industry as a sequestrant to maintain the quality of processed foods and prevent undesirable color changes.
Ethylenediaminetetraacetic acid disodium salt is employed in the automotive radiator repair industry to remove mineral deposits and improve the cooling system's efficiency.
Ethylenediaminetetraacetic acid disodium salt is used as a stabilizing agent in the formulation of certain eye drops and ointments, ensuring their safety and efficacy.
In water softening systems, Ethylenediaminetetraacetic acid disodium salt is used to replace hard water ions with sodium ions, reducing the effects of hard water on appliances and plumbing.

Ethylenediaminetetraacetic acid disodium salt is applied in chemical analysis as a masking agent to selectively protect specific metal ions from interference during analysis.
Ethylenediaminetetraacetic acid disodium salt can be used to adjust the pH of solutions and maintain the desired pH range in various chemical processes.
Ethylenediaminetetraacetic acid disodium salt is utilized in laboratory settings to chelate metal ions in samples, preventing their interference with analytical techniques.
The versatile chelation properties of Ethylenediaminetetraacetic acid disodium salt continue to make it an indispensable chemical in numerous scientific, industrial, and environmental applications.



DESCRIPTION


Ethylenediaminetetraacetic acid disodium salt, often abbreviated as Ethylenediaminetetraacetic acid disodium salt, is a chemical compound with the molecular formula C10H14N2Na2O8.
Ethylenediaminetetraacetic acid disodium salt is a synthetic organic compound derived from ethylenediamine and acetic acid.
Ethylenediaminetetraacetic acid disodium salt is a chelating agent, which means it can form stable complexes with metal ions by coordinating with their positively charged ions.

Ethylenediaminetetraacetic acid disodium salt, also known as Ethylenediaminetetraacetic acid disodium salt, is a synthetic organic compound.
Ethylenediaminetetraacetic acid disodium salt is derived from ethylenediamine and acetic acid through a series of chemical reactions.

Ethylenediaminetetraacetic acid disodium salt has a white, crystalline appearance and is water-soluble.
The chemical formula of Ethylenediaminetetraacetic acid disodium salt is C10H14N2Na2O8, indicating its composition of carbon, hydrogen, nitrogen, sodium, and oxygen atoms.

Ethylenediaminetetraacetic acid disodium salt is a chelating agent, meaning it can form stable complexes with metal ions.
Ethylenediaminetetraacetic acid disodium salt can bind to metal ions by coordinating with their positively charged ions.
In analytical chemistry, Ethylenediaminetetraacetic acid disodium salt serves as a titrant in complexometric titrations to determine metal ion concentrations.
In the food and beverage industry, Ethylenediaminetetraacetic acid disodium salt is used as a food additive (E385) to preserve product color and flavor.

Ethylenediaminetetraacetic acid disodium salt can prevent the oxidation of food components by binding to metal ions that catalyze oxidation reactions.
Ethylenediaminetetraacetic acid disodium salt is used in the pharmaceutical industry as a stabilizing agent and preservative in some medications.

In the cosmetics and personal care sector, Ethylenediaminetetraacetic acid disodium salt is utilized in various products as a stabilizer.
Medical applications include the use of Ethylenediaminetetraacetic acid disodium salt in chelation therapy to treat heavy metal poisoning.

Ethylenediaminetetraacetic acid disodium salt is also employed as an anticoagulant in blood collection tubes to prevent clotting.
In the detergents and cleaning industry, Ethylenediaminetetraacetic acid disodium salt enhances the performance of laundry detergents by binding to metal ions that can interfere with the cleaning process.
Ethylenediaminetetraacetic acid disodium salt plays a crucial role in water treatment by sequestering and removing metal ions to prevent contamination.
Ethylenediaminetetraacetic acid disodium salt is an odorless and tasteless substance.
Ethylenediaminetetraacetic acid disodium salt is highly soluble in water, resulting in easy preparation of aqueous solutions.

Ethylenediaminetetraacetic acid disodium salt is considered safe for use in many applications when used as directed.
Its ability to form stable metal complexes makes it a valuable tool for analytical chemistry.
Ethylenediaminetetraacetic acid disodium salt is an important component in the preservation of certain foods and beverages.

Its presence in cosmetics and pharmaceuticals helps maintain product quality and stability.
Chelation therapy using Ethylenediaminetetraacetic acid disodium salt can be an effective treatment for heavy metal poisoning.
In the detergent industry, it ensures that laundry products effectively remove stains and soils.

Ethylenediaminetetraacetic acid disodium salt, with its versatile applications, continues to be a valuable chemical compound in various fields.
The consistent use of Ethylenediaminetetraacetic acid disodium salt is essential in maintaining the quality and safety of products in which it is employed.



PROPERTIES


Chemical Formula: C10H14N2Na2O8
Molar Mass: Approximately 372.24 g/mol
Appearance: White, crystalline powder
Solubility: Highly soluble in water
Melting Point: Decomposes at high temperatures
Density: 1.01 g/cm³ (approximate)
pH Level: Typically, a 0.1 M solution of Ethylenediaminetetraacetic acid disodium salt has a pH of around 4.0 to 5.0.
Odor: Odorless
Taste: Tasteless
Hygroscopic: It can absorb moisture from the air.



FIRST AID


Inhalation:

If Ethylenediaminetetraacetic acid disodium salt dust or particles are inhaled and respiratory distress occurs, immediately move the affected person to an area with fresh air.
Keep the person calm and encourage them to breathe slowly and deeply.
If breathing difficulties persist or worsen, seek medical attention promptly.


Skin Contact:

In case of skin contact with Ethylenediaminetetraacetic acid disodium salt, remove contaminated clothing and rinse the affected area thoroughly with copious amounts of water for at least 15 minutes.
Use a mild soap if available to wash the skin gently.
If irritation or redness persists, seek medical attention.
Contaminated clothing should be removed and washed before reuse.


Eye Contact:

If Ethylenediaminetetraacetic acid disodium salt comes into contact with the eyes, rinse the affected eye(s) gently but thoroughly with lukewarm water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.
Seek immediate medical attention, even if there is no initial discomfort or redness.


Ingestion:

If Ethylenediaminetetraacetic acid disodium salt is ingested accidentally, do not induce vomiting unless directed to do so by medical professionals.
Rinse out the mouth with water if the substance has been swallowed.
Seek immediate medical attention or contact a poison control center.
Provide them with as much information as possible about the ingestion, including the amount ingested and the individual's weight.


General First Aid:

If any symptoms of exposure or irritation occur, such as difficulty breathing, skin irritation, eye irritation, or other discomfort, seek medical attention promptly.
Provide medical personnel with safety data sheets (SDS) or other relevant information about Ethylenediaminetetraacetic acid disodium salt for proper treatment guidance.
Keep contaminated clothing and personal protective equipment (PPE) separate from other items to avoid further contamination.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
When working with Ethylenediaminetetraacetic acid disodium salt, wear appropriate personal protective equipment, including safety goggles or a face shield, chemical-resistant gloves, and a lab coat or protective clothing.

Ventilation:
Use adequate ventilation systems, such as fume hoods or local exhaust, to minimize exposure to airborne particles and dust.

Avoid Inhalation:
Avoid breathing in dust, vapors, or aerosols.
Use respiratory protection (e.g., N95 respirators) if working with fine powders or in poorly ventilated areas.

Prevent Skin and Eye Contact:
Prevent skin and eye contact by wearing suitable protective gear.
In case of accidental contact, follow first aid procedures.

Use Caution with Open Flames:
Do not use open flames, as Ethylenediaminetetraacetic acid disodium salt may produce hazardous fumes or gases when heated.

Avoid Eating, Drinking, or Smoking:
Do not eat, drink, or smoke in areas where Ethylenediaminetetraacetic acid disodium salt is handled.
Wash hands thoroughly after handling, especially before eating or drinking.


Storage:

Container:
Store Ethylenediaminetetraacetic acid disodium salt in well-sealed, labeled containers that are specifically designed for chemical storage.
Containers should be made of compatible materials, such as glass or plastic.

Temperature:
Store the chemical in a cool, dry place, away from direct sunlight, heat sources, and temperature extremes.

Moisture Control:
Protect the substance from moisture by keeping the containers tightly closed.
Consider using desiccants to maintain a low-humidity environment.

Isolation:
Store Ethylenediaminetetraacetic acid disodium salt away from incompatible materials, such as strong acids, strong bases, and reactive metals, to prevent reactions.

Childproofing:
Keep the chemical out of reach of children and unauthorized personnel.

Fire Safety:
Store away from open flames, sparks, or sources of ignition.

Labeling:
Ensure that containers are clearly labeled with the product name, hazard warnings, and handling instructions.

Segregation:
Store Ethylenediaminetetraacetic acid disodium salt separately from food, beverages, and personal items to prevent contamination.

Shelf Life:
Be aware of the product's shelf life and adhere to expiration dates.
Dispose of expired or degraded material properly.

Spill Containment:
Have appropriate spill containment measures and cleanup materials readily available in case of accidental spills or leaks.



SYNONYMS


Disodium EDTA
Sodium EDTA
Edetate disodium
Ethylenediaminetetraacetate disodium salt
Edathamil disodium
Disodium ethylene-diamine-tetraacetate
Edetic acid disodium salt
Disodium salt of EDTA
Sodium ethylenediaminetetraacetate
Disodium edetate
Sodium ethylenediaminetetraacetate dihydrate
EDTA Na2
Edetic acid sodium salt
Ethylenediaminetetraacetic acid disodium salt dihydrate
Sequestrene sodium
Titriplex II
Versene disodium
Edathamil disodium salt
Edetic acid disodium
Ethylenediaminetetraacetic acid sodium salt
Disodium ethylenediaminetetraacetate dihydrate
Sequestrene Na2
Tetrasodium EDTA
Titriplex III
Versene disodium salt
Edathamil disodium salt
Sodium edetate
Sodium ethylenediaminetetraacetate
Disodium ethylenediaminetetraacetate
Edetic acid sodium salt
Sodium diethylenetriaminepentaacetate
Edetate sodium
Disodium ethylene diamine tetraacetate
Edetate disodium salt
Sodium ethylenediaminetetracetate
Disodium edathamil
Disodium ethylenediaminetetraacetate dihydrate
Sodium EDTA dihydrate
Disodium versenate
Sodium versenate
Diethylenetriamine pentaacetate disodium salt
Disodium diethylenetriaminepentaacetate
Tetrasodium ethylenediaminetetraacetate
Disodium ethylenediaminetetraacetate dihydrate
Sodium diethylenetriamine pentaacetate
Ethylenediaminetetraacetate disodium salt hydrate
Diethylenetriaminepentaacetate disodium
Sodium edetate dihydrate
Disodium ethylenediamine tetraacetate
Edetate disodium dihydrate
EDTA Na2
Ethylenebis(iminodiacetic acid) disodium salt
Ethylenediamine-N,N,N',N'-tetraacetic acid disodium salt
Disodium ethylenediamine-N,N,N',N'-tetraacetate
Edathamil disodium
Sodium ethylenediaminetetraacetate dihydrate
Diethylenetriamine pentaacetic acid disodium salt
Disodium edetate dihydrate
Sodium diethylenetriamine pentaacetate dihydrate
Disodium diethylenetriaminepentaacetate
Ethylenediaminetetraacetate sodium salt dihydrate
Disodium ethylenediaminetetraacetic acid dihydrate
Ethylenediaminetetraacetic acid disodium salt dihydrate
Disodium versenate dihydrate
Sodium versenate dihydrate
Diethylenetriaminepentaacetate disodium salt dihydrate
Sodium ethylenediaminetetraacetate dihydrate
Edetic acid disodium salt dihydrate
Diethylenetriamine pentaacetic acid sodium salt
Disodium diethylenetriaminepentaacetate dihydrate
Ethylenediaminetetraacetic acid disodium salt hydrate
Disodium ethylenediaminetetraacetate dihydrate hydrate
Sodium diethylenetriamine pentaacetate dihydrate hydrate
Edetate disodium dihydrate hydrate
Ethylenebis(iminodiacetic acid) disodium salt dihydrate


ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT
Ethylenediaminetetraacetic Acid Disodium Salt is a sequestrant and chelating agent whose complete name is disodium ethylenediamine tetraacetate.
Ethylenediaminetetraacetic Acid Disodium Salt occurs as a white crystalline, odorless powder with a slightly acidic taste.


CAS Number: 6381-92-6/139-33-3
EC Number: 205-358-3
MDL Number: MFCD00070672
Molecular Formula: C10H14N2Na2O8


Ethylenediaminetetraacetic Acid Disodium Salt is a nonhygroscopic powder that is colorless, odorless, and tasteless at recommended use levels.
Ethylenediaminetetraacetic Acid Disodium Salt is a 1% solution has a ph of 4.3–4.7.
Ethylenediaminetetraacetic Acid Disodium Salt is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.


Ethylenediaminetetraacetic Acid Disodium Salts are more stable than edetic acid.
However, Ethylenediaminetetraacetic Acid Disodium Salt loses water of crystallization when heated to 120°C.
Aqueous solutions of disodium edetate may be sterilized by autoclaving, and should be stored in an alkali-free container.
Ethylenediaminetetraacetic Acid Disodium Salt is hygroscopic and is unstable when exposed to moisture.


Ethylenediaminetetraacetic Acid Disodium Salt should be stored in a well-closed container in a cool, dry place.
Ethylenediaminetetraacetic Acid Disodium Salt is the disodium salt form of edetate, a heavy metal chelating agent.
Ethylenediaminetetraacetic Acid Disodium Salt, a heavy metal antagonist, chelates divalent and trivalent metals, forming soluble stable complexes.
Ethylenediaminetetraacetic Acid Disodium Salt inhibits enzymes, such as metalloproteases, that require divalent cations for activity.


Ethylenediaminetetraacetic Acid Disodium Salt is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in many industrial and personal care products.
Ethylenediaminetetraacetic Acid Disodium Salt, dihydrate is a chelating agent for metal ions in aqueous solution like Fe3+, Co2+, Fe2+, Mn2+, Ca2+, and Mg2+.
Ethylenediaminetetraacetic Acid Disodium Salt is a nonhygroscopic powder that is colorless, odorless, and tasteless at recommended use levels.


Ethylenediaminetetraacetic Acid Disodium Salt is a 1% solution has a ph of 4.3–4.7.
Ethylenediaminetetraacetic Acid Disodium Salt's function is comparable to that of disodium calcium edta.
Ethylenediaminetetraacetic Acid Disodium Salt is an organic sodium salt that is the anhydrous form of the disodium salt of ethylenediaminetetraacetic acid (EDTA).


Ethylenediaminetetraacetic Acid Disodium Salt has been in seed germination trials of plant species and in protein extraction from Moss, Physcomitrella paten.
Ethylenediaminetetraacetic Acid Disodium Salt is an aminopolycarboxylic acid and a hexadentate ligand.
Ethylenediaminetetraacetic Acid Disodium Salt chelates with metal ions, especially with cations to form an octahedral complex.


Ethylenediaminetetraacetic Acid Disodium Salt is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia.
Ethylenediaminetetraacetic Acid Disodium Saltis produced as several salts, e.g. ethylenediaminetetra-acetic acid disodium salt (EDTAS).
Ethylenediaminetetraacetic Acid Disodium Salt is soluble in Aqueous Base (Slightly), Water (Sparingly, Sonicated).



USES and APPLICATIONS of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
Ethylenediaminetetraacetic Acid Disodium Salt is a sterile chelating reagent.
Ethylenediaminetetraacetic Acid Disodium Salt is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Ethylenediaminetetraacetic Acid Disodium Salt is used in the following products: washing & cleaning products, coating products, adhesives and sealants, biocides (e.g. disinfectants, pest control products), fillers, putties, plasters, modelling clay, polishes and waxes, non-metal-surface treatment products, metal surface treatment products, air care products, textile treatment products and dyes and photo-chemicals.


Ethylenediaminetetraacetic Acid Disodium Salt is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids) and outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).


Release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and industrial abrasion processing with high release rate (e.g. sanding operations or paint stripping by shot-blasting).


Other release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).


Ethylenediaminetetraacetic Acid Disodium Salt can be found in complex articles, with no release intended: vehicles, machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and electrical batteries and accumulators.


Ethylenediaminetetraacetic Acid Disodium Salt can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture), metal (e.g. cutlery, pots, toys, jewellery), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), rubber (e.g. tyres, shoes, toys), wood (e.g. floors, furniture, toys) and plastic (e.g. food packaging and storage, toys, mobile phones).


Ethylenediaminetetraacetic Acid Disodium Salt is used in the following products: laboratory chemicals.
Ethylenediaminetetraacetic Acid Disodium Salt is used in the following areas: formulation of mixtures and/or re-packaging and mining.
Ethylenediaminetetraacetic Acid Disodium Salt is used for the manufacture of: chemicals.


Release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid and of substances in closed systems with minimal release.
Other release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Ethylenediaminetetraacetic Acid Disodium Salt is used in the following products: laboratory chemicals and cosmetics and personal care products.
Ethylenediaminetetraacetic Acid Disodium Salt has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt can occur from industrial use: formulation of mixtures and formulation in materials.
Ethylenediaminetetraacetic Acid Disodium Salt is used in the following areas: mining and building & construction work.


Ethylenediaminetetraacetic Acid Disodium Salt is used for the manufacture of: chemicals and mineral products (e.g. plasters, cement).
Release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt can occur from industrial use: as processing aid, in processing aids at industrial sites, in the production of articles and of substances in closed systems with minimal release.


Other release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt can occur from industrial use: manufacturing of the substance, formulation of mixtures and as an intermediate step in further manufacturing of another substance (use of intermediates).
Ethylenediaminetetraacetic Acid Disodium Salt also acts as a food additive.


Ethylenediaminetetraacetic Acid Disodium Salt is used to control the reaction of trace metals to include calcium and magnesium with other organic and inorganic components in food to prevent deterioration of color, texture, and development of precipitates and to prevent oxidation.
Ethylenediaminetetraacetic Acid Disodium Salt's function is comparable to that of disodium calcium edta.


Disodium Dihydrogen Ethylenediaminetetraacetate Solution is generally immediately available in most volumes.
High purity, submicron and nanopowder forms may be considered.
American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.


Ethylenediaminetetraacetic Acid Disodium Salt is used in detergents, liquid soap, shampoo, agricultural chemicals, fixer solution for development of color film, water cleaner, pH modifier.
When stating the redox reaction for the polymerization of butyl benzene rubber, Ethylenediaminetetraacetic Acid Disodium Salt is used as part of activator for the control of polymerization speed.


Ethylenediaminetetraacetic Acid Disodium Salt is widely used in textile industry.
Usually Ethylenediaminetetraacetic Acid Disodium Salt is applied to dissolve limescale.
Ethylenediaminetetraacetic Acid Disodium Salt is applied in textile industry, pulp and paper industry and also in chelation therapy.


In cosmetics, Ethylenediaminetetraacetic Acid Disodium Salt acts as a sequestering agent.
Ethylenediaminetetraacetic Acid Disodium Salt acts as a corrosion inhibitor to carbon steel in the industries.
Ethylenediaminetetraacetic Acid Disodium Salt is used as a preservative used in concentrations of 0.1 to 0.5 percent.
Ethylenediaminetetraacetic Acid Disodium Salt is a sequestrant and chelating agent whose complete name is disodium ethylenediamine tetraacetate.


Ethylenediaminetetraacetic Acid Disodium Salt is used to control the reaction of trace metals to include calcium and magnesium with other organic and inorganic components in food to prevent deterioration of color, texture, and development of precipitates and to prevent oxidation.
Ethylenediaminetetraacetic Acid Disodium Salt is widely used in textile industry.
Usually applied to dissolve limescale.


Ethylenediaminetetraacetic Acid Disodium Salt has a wide range of coordination properties, and can form stable chelates with almost all metal ions.
Ethylenediaminetetraacetic Acid Disodium Salt provides the possibility to determine elements widely (better than acid-base and precipitation methods).
Ethylenediaminetetraacetic Acid Disodium Salt chelating agents are widely used in water treatment, dyeing, oil cleaning, etc.


Ethylenediaminetetraacetic Acid Disodium Salt is used as a
biological buffer, Chelation/Complexation reagent.
Ethylenediaminetetraacetic Acid Disodium Salt is used widely in topical, oral, and parenteral pharmaceutical formulations; it is used extensively in cosmetic and food products.


Ethylenediaminetetraacetic Acid Disodium Salt is used in a greater number and variety of pharmaceutical formulations than edetic acid.
Ethylenediaminetetraacetic Acid Disodium Salt is poorly absorbed from the gastrointestinal tract and is associated with few adverse effects when used as excipients in pharmaceutical formulations.


Ethylenediaminetetraacetic Acid Disodium Salt is also used as a water softener as it will chelate calcium and magnesium ions present in hard water.
Ethylenediaminetetraacetic Acid Disodium Salt is also used therapeutically as an anticoagulant as it will chelate calcium and prevent the coagulation of blood in vitro.
Concentrations of 0.1% w/v are used in small volumes for hematological testing and 0.3% w/v in transfusions.


Ethylenediaminetetraacetic Acid Disodium Salt is used as chelating agent for metals and as pharmaceutic aid (chelating agent).
Ethylenediaminetetraacetic Acid Disodium Salt is used as preservative in cosmetic products.
Ethylenediaminetetraacetic Acid Disodium Salt is also used as anticoagulant.
Ethylenediaminetetraacetic Acid Disodium Salt is used as a chelating agent (metal); pharmaceutic aid (chelating agent).


Ethylenediaminetetraacetic Acid Disodium Salt is applied in textile industry, pulp and paper industry and also in chelation therapy.
In cosmetics, Ethylenediaminetetraacetic Acid Disodium Salt acts as a sequestering agent.
Ethylenediaminetetraacetic Acid Disodium Salt acts as a corrosion inhibitor to carbon steel in the industries.
Ethylenediaminetetraacetic Acid Disodium Salt also acts as a food additive.


Ethylenediaminetetraacetic Acid Disodium Salt has also been used in lysis and vacuole buffer for the isolation of vacuoles from Petunia petals.
Ethylenediaminetetraacetic Acid Disodium Salt is used as a chelator of divalent cations.
Ethylenediaminetetraacetic Acid Disodium Salt inhibits enzymes, such as metalloproteases, that require divalent cations for activity.


Ethylenediaminetetraacetic Acid Disodium Salt uses and applications include: Chelating agent in cosmetics, pharmaceuticals, water treatment, textiles, soapsdetergents, electroless copper plating, polymer production, disinfectants, pulppaper, enhanced oil recovery, metal cleaningprotection; scale inhibitor (boiler water treatment); textileleather processing auxiliaries; antioxidant for cosmetics; prevents metal-catalyzed oxidative breakdown; preservative, preservative synergist, antioxidant, stabilizer, chelant, sequestrant in foods; hog scald agent; anticoagulant; pharmaceutic aid; viscous control agent; chelating agent in food-contact paperpaperboard manufacturing; in cellophane for food packaging; chelating agentsequestrant in lubricants for incidental food-contact use; in food packaging adhesives; in surfactant lubricants for manufacturing of food-contact metallic articles.


Ethylenediaminetetraacetic Acid Disodium Salt is widely used as a chelating agent in a variety of pharmaceutical preparations, including mouthwashs, ophthalmic preparations and topical preparations.
Ethylenediaminetetraacetic Acid Disodium Salt is also used as a stabilizer for various emulsions.
Ethylenediaminetetraacetic Acid Disodium Salt is used in several industrial applications attributing to its high ability to bind to most of metal cations.


Ethylenediaminetetraacetic Acid Disodium Salt is used as chelating agents in cosmetic formulations.
EDTAS is a preservative, sequestrant, and stabilizer in foods.
EDTA is added to ascorbic acid-disodium benzoate containing soft drinks to mitigate the formation of benzene.
EDTA and its salts are used as a component in the production of food-contact paper and paperboard.


EDTAS is permitted in the feed and drinking water of animals and/or for the treatment of food-producing animals.
In the textile industry, EDTA and its salts prevent metal ion impurities from changing colors of dyed products.
In the pulp and paper industry, EDTA and its salts inhibit the ability of metal ions from catalyzing the disproportionation of hydrogen peroxide (a typical bleaching agent).


EDTA is used in synthetic rubber manufacture.
EDTA is also used as a corrosion inhibitor to carbon steel in the industries.
Ethylenediaminetetraacetic Acid Disodium Salt chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests.
Ethylenediaminetetraacetic Acid Disodium Salt enhances the antibacterial activity of lysozyme.


Ethylenediaminetetraacetic Acid Disodium Salt is used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease.
Ethylenediaminetetraacetic Acid Disodium Salt chelation therapy may also protect from oxidative damage during blood and lipid peroxidation in liver fibrosis.


Ethylenediaminetetraacetic Acid Disodium Salt is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in many industrial and personal care products.
Ethylenediaminetetraacetic Acid Disodium Salt is used as a stabilizer for various emulsions.


Ethylenediaminetetraacetic Acid Disodium Salt is added to foods and personal care products.
Ethylenediaminetetraacetic Acid Disodium Salt is used in aqueous solutions with other reagents and inert materials for the preparation of cleaning mixtures and poultices to be applied to stone surfaces and frescoes.


Ethylenediaminetetraacetic Acid Disodium Salt, for its property of complexing calcium within crusts and for its good solubility (better than tetrasodium salt), is used in the AB 57 poultice (I.C.R. formulation - Rome).
Ethylenediaminetetraacetic Acid Disodium Salt is besides a strong chelating agent of a great many metallic cations, as iron and copper; this property can be utilized to remove stains of rust or copper green from stone surfaces, wood, plasters, etc…


-Personal care & skincare products:
Binding to free metal ions and serves as a purifying agent and preservative.
-Shampoos and soaps:
Reducing the "hardness" (or presence of metal cations) in tap water so that other ingredients can work to cleanse more efficiently.


-Laundry detergents:
To soften water that comes into contact with it so the other active ingredients can cleanse better.
-Textiles:
Preventing the discolouring of dyed fabrics by removing harmful free metal ions and getting rid of residue left on industrial equipment.


-Agriculture Fertilizers:
Ethylenediaminetetraacetic Acid Disodium Salt is mainly used as foliar fertilizers, water-soluble fertilizers to supply trace elements for vegetables, crops, and fruits.
-Foods:
Ethylenediaminetetraacetic Acid Disodium Salt is used for chelating metal ions, removing heavy metals of foods.
EDTA metal salts e.g. Ca, Zn, Fe, are used for supplying micronutrients for human.


-Cosmetic Uses of Ethylenediaminetetraacetic Acid Disodium Salt:
*chelating agents
*viscosity controlling agents


-Biochem/physiol Actions of Ethylenediaminetetraacetic Acid Disodium Salt:
Ethylenediaminetetraacetic Acid Disodium Salt has the ability to block the binding of vasoactive intestinal peptide to macrophage membranes.
Ethylenediaminetetraacetic Acid Disodium Salt is mainly used in the purification of protein, to remove divalent cations and also to prevent protease activity.


-Pharmaceutical Applications of Ethylenediaminetetraacetic Acid Disodium Salt:
Ethylenediaminetetraacetic Acid Disodium Salt is used as a chelating agent in a wide range of pharmaceutical preparations, including mouthwashes, ophthalmic preparations, and topical preparations, typically at concentrations between 0.005 and 0.1% w/v.
Ethylenediaminetetraacetic Acid Disodium Salt forms stable water-soluble complexes (chelates) with alkaline earth and heavy-metal ions.
The chelated form of Ethylenediaminetetraacetic Acid Disodium Salt has few of the properties of the free ion, and for this reason chelating agents are often described as ‘removing’ ions from solution, a process known as sequestering.
The stability of the metal–edetate complex is dependent on the metal ion involved and the pH.


-Veterinary Drugs and Treatments:
Ethylenediaminetetraacetic Acid Disodium Salt is a chelating agent that is also used to stop the melting effect of collagenases and proteases on the cornea.
Ethylenediaminetetraacetic Acid Disodium Salt is useful in halting melting through inhibition of matrix metalloproteinases, but is not felt to be useful for melting caused by infectious agents.
As the effect of Ethylenediaminetetraacetic Acid Disodium Salt on metalloproteinases is reversible, it must be administered several times daily to be effective.


-Industrial Applications of Ethylenediaminetetraacetic Acid Disodium Salt:
Ethylenediaminetetraacetic Acid Disodium Salt is used in cleaners, detergent, fertilizers, fixer solution for development of colour film, water cleaner and pH modifier.
Ethylenediaminetetraacetic Acid Disodium Salt is also used in redox reaction for the polymerization of butyl benzene rubber.
Ethylenediaminetetraacetic Acid Disodium Salt is used as part of activator for the control of polymerization speed.


-Personal Care Applications of Ethylenediaminetetraacetic Acid Disodium Salt:
Ethylenediaminetetraacetic Acid Disodium Salt is used in Cosmetics to increase effectiveness and improve stability of bar and solid soaps, bath preparations; creams, oils, hair care products and many other personal care formulations.
-Application of Ethylenediaminetetraacetic Acid Disodium Salt:
*Surfactants & Emulsifiers



FUNCTIONS OF ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
*Preservative
*Scale Inhibitor
*Stabilizer
*Lubricant



INDUSTRY:
*Cosmetic
*Plating
*Pharmaceutical
*Water Treatment
*Textiles
*Adhesives
*Detergent



INCOMPATIBILITIES OF ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
Ethylenediaminetetraacetic Acid Disodium Salt behaves as a weak acid, displacing carbon dioxide from carbonates and reacting with metals to form hydrogen.
Ethylenediaminetetraacetic Acid Disodium Salt is incompatible with strong oxidizing agents, strong bases, metal ions, and metal alloys.



MANUFACTURING PROCESS OF ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
10 mols of ethylene diamine as a 30% aqueous solution and 4 mols of solid caustic soda are placed in a steam heated kettle supplied with an agitator.
8 mols of sodium cyanide as a concentrated water solution (about 30%) are added and the solution heated to 60°C.
About a 10 inch vacuum is applied to bring the liquid to incipient boiling.

Formaldehyde (7.5 mols of 37% to 40% aqueous solution) is slowly added, the temperature being held at 60°C, and the solution vigorously stirred.
Then, when the evolution of ammonia has substantially stopped, an additional 8 mols of sodium cyanide, followed by 8 mols of formaldehyde are added as before.
This is continued until 40 mols of cyanide and 40 mols of formaldehyde have been added.

Then at the end about 2 mols more of formaldehyde are added, making 42 mols in all, to remove any last traces of cyanide.
About 8 to 10 hours are required to complete the reaction.
The resulting product, referred to herein as the crude reaction product, is essentially an aqueous solution of the sodium salt of ethylene diamine tetracetic acid.

To 1,000 g of the crude reaction product are added 264 g of ethylene diamine tetracetic acid.
The mixture is preferably heated to incipient boiling to increase the rate of reaction, and then the mixture is allowed to cool and crystallize.
The crystals formed are filtered off, washed with the smallest possible amount of ice water, and dried to a constant weight, which is 452 g.

A representative sample of the product so prepared showed, upon analysis, 13.26% sodium against a theoretical of 13.70% for the disodium salt.
The dialkali salt has a pH of about 5.3 and behaves like a weak acid, displacing CO2 from carbonates and reacting with metals to form hydrogen.
Ethylenediaminetetraacetic Acid Disodium Salt is a white crystalline solid.



PRODUCTION METHODS OF ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
Ethylenediaminetetraacetic Acid Disodium Salt may be prepared by the reaction of edetic acid and sodium hydroxide.



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
Formula: [CH2N(CH2COOH)CH2COONa]2·2H2O
Appearance: white crystals
Assay: 99% min.
Specific gravity: 0.8 - 1.1 kg/l at 20°C
pH: 4,5-5 in 10% aqueous solution
Appearance: white crystalline powder (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in: water, 1e+006 mg/L @ 25 °C (est)
Insoluble in: alcohol
Form: powder
Colour: white
Odour: product specific
Odour threshold:
not determined
pH value: 4 - 5 (DIN 19268)
Melting point: 248 °C (dec.)(lit.)
Boiling point: >100 °C
Density: 1.01 g/mL at 25 °C

vapor pressure: 0Pa at 25℃
storage temp.: 2-8°C
solubility: H2O: clear, colorless
form: solution
color: ≤5 (0.5 M)(APHA)
Water Solubility: Miscible with water.
BRN: 3822669
Stability: Hygroscopic
LogP: -4.3 at 25℃
Self ignition: not self-igniting
Test type: Spontaneous selfignition at room-temperature.
Temperature: > 400 °C Test type: Self-ignition at high
Pressure: 1.013,25 hPa temperatures.
No self ignition was observed up to (Method: Regulation
the specified temperature. 440/2008/EC, A.16)
Viscosity, dynamic:
Study scientifically not justified.
Viscosity, kinematic: not applicable, the product is a solid

Explosion hazard: Product is not explosive, however a dust explosion could result from an air / dust mixture.
Fire promoting properties: Based on its structural properties the product is not classified as oxidizing.
Other information:
Self heating ability: It is not a substance capable of spontaneous heating.
Minimum ignition energy: > 4 J (DIN EN 13821) (1.013,25 hPa, 20 °C)
Bulk density: approx. 950 kg/m3 (DIN ISO 697)
Surface tension: Based on chemical structure, surface activity is not to be expected.
Grain size distribution: particles < 100 µm approx. 29 %
particles < 10 µm approx. 1,2 %
particles < 4 µm approx. 0,2 %
Melting Point: >250°C (dec.)
Density: 1.01 g/mL at 25°C
InChI Key: ZGTMUACCHSMWAC-UHFFFAOYSA-L
Stability: Stable.
Molecular Formula: C₁₀H₁₄N₂Na₂O₈
Appearance: White to Off-White Solid
Melting Point: >250°C (dec.)
Molecular Weight: 336.21
Storage: 4°C, Hygroscopic
Solubility: Aqueous Base (Slightly), Water (Sparingly, Sonicated)
Stability: Hygroscopic



FIRST AID MEASURES of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Description of first aid measures:
Remove contaminated clothing.
*If inhaled:
Keep patient calm, remove to fresh air, seek medical attention.
*On skin contact:
Wash thoroughly with soap and water.
*On contact with eyes:
Wash affected eyes for at least 15 minutes under running water with eyelids held open.
*On ingestion:
Immediately rinse mouth and then drink 200-300 ml of water, seek medical attention.
-Indication of any immediate medical attention and special treatment needed:
*Treatment:
Treat according to symptoms, with no known specific antidote.



ACCIDENTAL RELEASE MEASURES of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Personal precautions, protective equipment and emergency procedures:
Use personal protective clothing.
-Environmental precautions:
Contain contaminated water/firefighting water.
Do not discharge into drains/surface waters/groundwater.
-Methods and material for containment and cleaning up:
*For small amounts:
Pick up with suitable appliance and dispose of.
*For large amounts:
Contain with dust binding material and dispose of.
Dispose of absorbed material in accordance with regulations.



FIRE FIGHTING MEASURES of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Extinguishing media:
*Suitable extinguishing media:
dry powder, foam
-Advice for fire-fighters:
*Further information:
Contaminated extinguishing water must be disposed of in accordance with official regulations.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Exposure controls:
--Personal protective equipment:
*Hand protection:
Chemical resistant protective gloves.
*Supplementary note:
Manufacturer's directions for use should be observed because of great diversity of types.
*Eye protection:
Safety glasses with side-shields (frame goggles)
-General safety and hygiene measures:
Wearing of closed work clothing is recommended.
No eating, drinking, smoking or tobacco use at the place of work.
Handle in accordance with good industrial hygiene and safety practice.



HANDLING and STORAGE of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Conditions for safe storage, including any incompatibilities:
*Suitable materials for containers:
Low density polyethylene (LDPE), glass, Paper/Fibreboard, High density polyethylene (HDPE)
-Further information on storage conditions:
Keep container tightly closed and dry; store in a cool place.



STABILITY and REACTIVITY of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Reactivity:
No hazardous reactions if stored and handled as prescribed/indicated.
*Corrosion to metals:
No corrosive effect on metal.
-Chemical stability:
The product is stable if stored and handled as prescribed/indicated.



SYNONYMS:
Disodium EDTA
Isodium dihydrogen ethylenediaminetetraacetate
Edetic acid disodium salt
EDTA disodium salt
(Ethylenedinitrilo)tetraacetic acid disodium salt
Disodium Edetate
Chelaplex
Chelaplex III
Chelaton III
Chelest 200
Chelest 2B-SD
Chelest 2BS
Chelest B; Clewat N
Clewat N 2
Complexon III
Disodium (Ethylenedinitrilo)tetraacetate
Disodium EDTA
Disodium Diacid Ethylenediaminetetraacetate
Disodium Dihydrogen Ethylenediaminetetraacetate
1,2-DIAMINOETHANE-N,N,N',N'-TETRA-ACETIC ACID DISODIUM SALT
1,2-DIAMINOETHANE-N,N,N',N'-TETRA-ACETIC ACID DISODIUM SALT 2H2O
4C EDTA
COMPLEXONE III
COMPLEXONE III(R)
DISODIUM DIHYDROGEN ETHYLENEDIAMINE TETRAACETATE
DISODIUM DIHYDROGEN ETHYLENEDIAMINETETRAACETATE DIHYDRATE
DISODIUM DIHYDROGEN ETHYLENEDIAMINETETRA-ACETIC DIHYDRATE
DISODIUM EDETATE
DISODIUM EDETATE DIHYDRATE
DISODIUM EDTA
DISODIUM ETHYLENEDIAMINETETRAACETATE
DISODIUM ETHYLENEDIAMINETETRAACETATE DIHYDRATE
Disodium ethylenediaminetetraacetic acid
DISODIUM (ETHYLENEDINITRILO)TETRAACETATE, DIHYDRATE
EDATHAMIL DISODIUM SALT DIHYDRATE
EDETATE DISODIUM
EDETATE DISODIUM, DIHYDRATE
EDETATE DISODIUM DIHYDROGEN, DIHYDRATE
EDETATE DISODIUM SALT DIHYDRATE
(Ethylenedinitrilo)tetraacetic acid disodium salt
EDTA disodium salt, EDTA-Na2
(Ethylenedinitrilo)tetraacetic Acid Disodium Salt
EDTA Disodium Salt; EDTA-Na2
Ethylenediamine-N,N,N',N'-tetraacetic Acid Disodium Salt
EDNRA
1,2-Diaminoethane-N,N,N',N'-tetra-acetic Acid Sisodium Salt
ETHYLENEBIS(IMINODIACETIC ACID)DISODIUM SALT
ETHYLENEDIAMINETETRAACETIC ACID, 2NA, DIHYDRATE
ETHYLENE DIAMINETETRA ACETIC ACID DISODIUM
ETHYLENEDIAMINE TETRAACETIC ACID DISODIUM DIHYDRATE
ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT
ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT-2-HYDRATE
ETHYLENEDIAMINE-N,N,N',N'-TETRAACETIC ACID DISODIUM SALT
ETHYLENEDIAMINETETRAACETATE DISODIUM SALT
(ETHYLENENDINITRILO)TETRAACETIC ACID, DISODIUM SALT, DIHYDRATE
(ETHYLENEDINITRILO)TETRAACETIC DISODIUM, DIHYDRATE
Disodium EDTA
Disodium dihydrogen ethylenediaminetetraacetate
Disodium edetate
Disodium ethylenediamine tetraacetate
Edetate disodium
Ethylenediaminetetraacetic acid, disodium salt (Ethylenedinitrilo) tetraacetic acid, sodium salt
Glycine, N,N-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt dihydrate
Chelaplex
Chelaplex III
Chelaton III
Chelest B
Disodium (Ethylenedinitrilo)tetraacetate
Disodium EDTA
Disodium Diacid Ethylenediaminetetraacetate
Disodium Dihydrogen Ethylenediaminetetraacetate
Disodium Edathamil
Disodium Edetate
Disodium Ethylenediamine-N,N,N',N'-tetraacetate
Disodium Ethylenediaminetetraacetate
Disodium Ethylenediaminetetraacetic Acid Salt
Disodium Sequestrene
Disodium Tetracemate
Disodium Versenate
Disodium Versene
EDTA Disodium Salt
Edathamil Disodium
Edetate Disodium
Endrate Disodium
Ethylenedinitrilotetraacetate Disodium
EDTA-2NA
DISODIUM EDTA
DISODIUM EDETATE
ETA;EDETATE DISODIUM
EDTA DISODIUM
EDTA DISODIUM SALT
TITRIPLEX III
DISODIUM ETHYLENEDIAMINETETRAACETATE
EDTA NA2
Ethylenediaminetetra-acetic acid disodium salt dihydrate
Edetate disodium dihydrate
Ethylenediaminetetraacetic acid, disodium salt, dihydrate
Kestranal 2S 2 H2O
Ethylenedinitrilotetra-acetic acid disodium salt dihydrate
Titriplex III
Kestranal 2S dihydrate
Edetic acid disodium salt dihydrate
Disodium dihydrogen ethylenediaminetetraacetate dihydrate




ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT (EDTA - 2NA)
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is used in several industrial applications attributing to its high ability to bind to most of metal cations.
EDTA is produced as several salts, e.g. Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na).
EDTA and Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na)'s salts are used as chelating agents in cosmetic formulations.

CAS: 139-33-3
MF: C10H14N2Na2O8
MW: 336.21
EINECS: 205-358-3

Synonyms
SEQUESTRENE NA2;SODIUM (DI) ETHYLENEDIAMINE TETRAACETATE DIHYDRATE;VERSENE NA, DIHYDRATE;VERSENE DISODIUM;WANKLYN'S EDTA;Ceftriaxone Impurity 21(EDTA Disodium);disodium ethylenediamintetraacetate;EDTA two sodium;Edetate disodium;139-33-3;EDTA disodium salt;Disodium edetate;Edta disodium;Titriplex III;Disodium EDTA;Disodium edta,anhydrous;Cheladrate;Ethylenediaminetetraacetic acid disodium salt;Disodium versene;Endrate disodium;Sodium versenate;Disodium salt of EDTA;Metaquest B;Kiresuto B;Chelaplex III;Chelest B;Diso-Tate;Komplexon III;Chelaton III;Clewat N;Versene NA;Triplex III;Chelaton 3;Disodium versenate;Edathamil disodium;Trilon BD;Versene Na2;Zonon D;Edetate disodium anhydrous;Dotite 2NA;Selekton B 2;Disodium sequestrene;Disodium tetracemate;Mavacid ED 4;Versonol 120;Disodium ethylenediaminetetraacetate;Chelest 200;Sequestrene sodium 2;Veresene disodium salt;Disodium EDTA dihydrate;Perma Kleer Di Crystals;Edetic acid disodium salt;Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt;Ethylenediaminetetraacetic acid, disodium salt;CCRIS 3658;E.D.T.A. disodique;EDTA-Na2;Disodium dihydrogen ethylenediaminetetraacetate;NSC 2760;EDTA disodium salt (anhydrous);Anhydrous disodium edetate;EINECS 205-358-3;Disodium ethylenediamine-N,N,N',N'-tetraacetate;Perma kleer 50 crystals disodium salt;UNII-8NLQ36F6MM;Disodium ethylenediaminetetraacetic acid;Edetate disodium, anhydrous;Ethylene diamine tetraacetic acid, disodium salt;Disodium (ethylenedinitrilo)tetraacetate;Edetic Acid, Disodium Salt;CBC 50152966
;DR-16133;Ethylenediaminetetraacetate, disodium salt;Disodium diacid ethylenediaminetetraacetate;MFCD00070672;AI3-18049;Disodium (ethylenedinitrilo)tetraacetic acid;Dinatrium ethylendiamintetraacetat;HSDB 8013;Trilon B;Disodium dihydrogen(ethylenedinitrilo)tetraacetate;Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, disodium salt;Endrate (TN);Disodium edathamil;6381-92-6;disodium 2-({2-[(carboxylatomethyl)(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetate;Tetracemate disodium;Na2-EDTA
;N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine) disodium salt;EC 205-358-3;Edta disodium salt anhydrous;8NLQ36F6MM;CHEBI:64734;Disodium N,N'-1,2-ethanediylbis(N-(carboxymethyl)glycine);ACETIC ACID, (ETHYLENEDINITRILO)TETRA-, DISODIUM SALT;NSC-2760;E.D.T.A. disodique [French];F 1 (VAN);ethylenediamine tetraacetic acid disodium salt;Dinatrium ethylendiamintetraacetat [Czech];Ethylenebis(iminodiacetic acid) disodium salt;disodium 2-((2-((carboxylatomethyl)(carboxymethyl)amino)ethyl(carboxymethyl)amino)acetate;(Ethylenedinitrilo)-tetraacetic acid disodium salt;Na2EDTA;0.5M Sodium EDTA;Disodium edetate (TN);Na2.EDTA;CHEMBL1749;DTXSID9027073;disodium ethylenediamine-tetraacetate;AKOS016370696;DB14600;SB40706;69772-70-9;E386;ethylenediaminetetracetic acid disodium salt;DB-042467;NS00078150;EN300-35828;ethylenediaminetetra-acetic acid disodium salt;D03945;P17519;J-007267;J-521348;Q4532977;disodium 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetate;Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, sodium salt (1:2);(Ethylenedinitrilo)tetraacetic acid disodium salt, EDTA disodium salt, EDTA-Na2;2-[2-(Carboxylatomethyl-(carboxymethyl)amino)ethyl-(carboxymethyl)amino]acetate disodium;disodium;2-[2-[carboxylatomethyl(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetate;DISODIUM 2-({2-[(CARBOXYLATOMETHYL)(CARBOXYMETHYL)AMINO]ETHYL(CARBOXYMETHYL)AMINO)ACETATE

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a preservative, sequestrant, and stabilizer in foods.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is added to ascorbic acid-disodium benzoate containing soft drinks to mitigate the formation of benzene.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) and its salts are used as a component in the production of food-contact paper and paperboard.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is permitted in the feed and drinking water of animals and/or for the treatment of food-producing animals.
In the textile industry, EDTA and Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na)'s salts prevent metal ion impurities from changing colors of dyed products.
In the pulp and paper industry, EDTA and Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na)'s salts inhibit the ability of metal ions from catalyzing the disproportionation of hydrogen peroxide (a typical bleaching agent).
EDTAS is used in synthetic rubber manufacture.

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is also used as a corrosion inhibitor to carbon steel in the industries.
As an anticoagulant, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) and tripotassium salts of EDTA are most commonly used.
An organic sodium salt that is the anhydrous form of the disodium salt of Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na).
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a calcium ion chelator, that has a low molecular mass of 292.24 Da.
​Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in many industrial and personal care products.

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na), also called EDTA acid after its own abbreviation, is an aminopolycarboxylic acid with the formula [CH2N(CH2CO2H)2]2.
This white, water-insoluble solid is widely used to bind to iron (Fe2+/Fe3+) and calcium ions (Ca2+), forming water-soluble complexes even at neutral pH.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is thus used to dissolve Fe- and Ca-containing scale as well as to deliver iron ions under conditions where its oxides are insoluble.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is available as several salts, notably disodium EDTA, sodium calcium edetate, and tetrasodium EDTA, but these all function similarly.

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) Chemical Properties
Melting point: 248 °C (dec.)(lit.)
Boiling point: >100 °C
Density: 1.01 g/mL at 25 °C
Vapor pressure: 0Pa at 25℃
Storage temp.: 2-8°C
Solubility H2O: clear, colorless
Form: solution
Color: ≤5 (0.5 M)(APHA)
Odor: at 100.00?%. odorless
Water Solubility: Miscible with water.
BRN: 3822669
Stability: Hygroscopic
LogP: -4.3 at 25℃
CAS DataBase Reference: 139-33-3(CAS DataBase Reference)
EPA Substance Registry System: Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) (139-33-3)
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) occurs as a white crystalline, odorless powder with a slightly acidic taste.

uses
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is an aminopolycarboxylic acid and a hexadentate ligand.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) chelates with metal ions, especially with cations to form an octahedral complex.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) enhances the antibacterial activity of lysozyme.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) chelation therapy may also protect from oxidative damage during blood and lipid peroxidation in liver fibrosis.

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a preservative used in concentrations of 0.1 to 0.5 percent.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a sequestrant and chelating agent whose complete name is disodium ethylenediamine tetraacetate.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a nonhygroscopic powder that is colorless, odorless, and tasteless at recommended use levels. A 1% solution has a ph of 4.3–4.7.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is used to control the reaction of trace metals to include calcium and magnesium with other organic and inorganic components in food to prevent deterioration of color, texture, and development of precipitates and to prevent oxidation.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na)'s function is comparable to that of disodium calcium edta.

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is widely used in textile industry. Usually applied to dissolve limescale.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is applied in textile industry, pulp and paper industry and also in chelation therapy.
In cosmetics, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) acts as a sequestering agent.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) acts as a corrosion inhibitor to carbon steel in the industries.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) also acts as a food additive.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) has been in seed germination trials of plant species and in protein extraction from Moss, Physcomitrella paten.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) has also been used in lysis and vacuole buffer for the isolation of vacuoles from Petunia petals.

Pharmaceutical Applications
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is used as a chelating agent in a wide range of pharmaceutical preparations, including mouthwashes, ophthalmic preparations, and topical preparations, typically at concentrations between 0.005 and 0.1% w/v.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) forms stable water-soluble complexes (chelates) with alkaline earth and heavy-metal ions.
The chelated form has few of the properties of the free ion, and for this reason chelating agents are often described as ‘removing’ ions from solution, a process known as sequestering.
The stability of the metal–edetate complex is dependent on the metal ion involved and the pH.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is also used as a water softener as it will chelate calcium and magnesium ions present in hard water.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is also used therapeutically as an anticoagulant as it will chelate calcium and prevent the coagulation of blood in vitro.
Concentrations of 0.1% w/v are used in small volumes for hematological testing and 0.3% w/v in transfusions.

Industrial Applications
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is used in cleaners, detergent, fertilizers, fixer solution for development of colour film, water cleaner and pH modifier.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is also used in redox reaction for the polymerization of butyl benzene rubber, it is used as part of activator for the control of polymerization speed.

Uses
Textiles and paper
In industry, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is mainly used to sequester (bind or confine) metal ions in aqueous solution.
In the textile industry, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) prevents metal ion impurities from modifying colours of dyed products.
In the pulp and paper industry, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) inhibits the ability of metal ions, especially Mn2+, from catalysing the disproportionation of hydrogen peroxide, which is used in chlorine-free bleaching.

Food
In a similar manner, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is added to some food as a preservative or stabiliser to prevent catalytic oxidative decolouration, which is catalysed by metal ions.

Water softener
The reduction of water hardness in laundry applications and the dissolution of scale in boilers both rely on Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) and related complexants to bind Ca2+, Mg2+, as well as other metal ions.
Once bound to Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na), these metal complexes are less likely to form precipitates or to interfere with the action of the soaps and detergents.
For similar reasons, cleaning solutions often contain Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na).
In a similar manner Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is used in the cement industry for the determination of free lime and free magnesia in cement and clinkers.

The solubilisation of Fe3+ ions at or below near neutral pH can be accomplished using EDTA.
This property is useful in agriculture including hydroponics.
However, given the pH dependence of ligand formation, EDTA is not helpful for improving iron solubility in above neutral soils.
Otherwise, at near-neutral pH and above, iron(III) forms insoluble salts, which are less bioavailable to susceptible plant species.

Manufacturing Process
10 mols of ethylene diamine as a 30% aqueous solution and 4 mols of solid caustic soda are placed in a steam heated kettle supplied with an agitator.
8 mols of sodium cyanide as a concentrated water solution (about 30%) are added and the solution heated to 60°C.
About a 10 inch vacuum is applied to bring the liquid to incipient boiling.
Formaldehyde (7.5 mols of 37% to 40% aqueous solution) is slowly added, the temperature being held at 60°C, and the solution vigorously stirred.
Then, when the evolution of ammonia has substantially stopped, an additional 8 mols of sodium cyanide, followed by 8 mols of formaldehyde are added as before.
This is continued until 40 mols of cyanide and 40 mols of formaldehyde have been added.
Then at the end about 2 mols more of formaldehyde are added, making 42 mols in all, to remove any last traces of cyanide.

About 8 to 10 hours are required to complete the reaction.
The resulting product, referred to herein as the crude reaction product, is essentially an aqueous solution of the sodium salt of ethylene diamine tetracetic acid.
To 1,000 g of the crude reaction product are added 264 g of ethylene diamine tetracetic acid.
The mixture is preferably heated to incipient boiling to increase the rate of reaction, and then the mixture is allowed to cool and crystallize.
The crystals formed are filtered off, washed with the smallest possible amount of ice water, and dried to a constant weight, which is 452 g.
A representative sample of the product so prepared showed, upon analysis, 13.26% sodium against a theoretical of 13.70% for the disodium salt.
The dialkali salt has a pH of about 5.3 and behaves like a weak acid, displacing CO2 from carbonates and reacting with metals to form hydrogen.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a white crystalline solid.

Synthesis
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) was first described in 1935 by Ferdinand Münz, who prepared the compound from ethylenediamine and chloroacetic acid.
Today, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is mainly synthesised from ethylenediamine (1,2-diaminoethane), formaldehyde, and sodium cyanide.
This route yields the tetrasodium Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na), which is converted in a subsequent step into the acid forms:

H2NCH2CH2NH2 + 4 CH2O + 4 NaCN + 4 H2O → (NaO2CCH2)2NCH2CH2N(CH2CO2Na)2 + 4 NH3
(NaO2CCH2)2NCH2CH2N(CH2CO2Na)2 + 4 HCl → (HO2CCH2)2NCH2CH2N(CH2CO2H)2 + 4 NaCl
This process is used to produce about 80,000 tonnes of EDTA each year.
Impurities cogenerated by this route include glycine and nitrilotriacetic acid; they arise from reactions of the ammonia coproduct.

Biochem/physiol Actions
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) has the ability to block the binding of vasoactive intestinal peptide to macrophage membranes.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is mainly used in the purification of protein, to remove divalent cations and also to prevent protease activity.

Side effects
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) exhibits low acute toxicity with LD50 (rat) of 2.0 g/kg to 2.2 g/kg.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) has been found to be both cytotoxic and weakly genotoxic in laboratory animals. Oral exposures have been noted to cause reproductive and developmental effects.
The same study also found that both dermal exposure to Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) in most cosmetic formulations and inhalation exposure to EDTA in aerosolised cosmetic formulations would produce exposure levels below those seen to be toxic in oral dosing studies.

Veterinary Drugs and Treatments
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a chelating agent that is also used to stop the melting effect of collagenases and proteases on the cornea.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is useful in halting melting through inhibition of matrix metalloproteinases, but is not felt to be useful for melting caused by infectious agents.
As the effect of Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) on metalloproteinases is reversible, it must be administered several times daily to be effective.
ETHYLENEDIAMINTETRAACETIC ACID
1,2-Diaminoethane, 1,2-Ethanediamine; 1,2-Ethylenediamine; 1,2-Diaminoethane; EDA; Ethane-1,2-diamine; Aethaldiamin; Aethylenediamin; 1,2-diaminoaethan; 1,2-Diamino-ethaan; 1, 2-Diamino-Ethano; Dimethylenediamine; Ethyleendiamine; Ethylene-diamine; β-Aminoethylamine CAS NO:107-15-3
Ethylenediamine
1,2-Diaminoethane, 1,2-Ethanediamine; 1,2-Ethylenediamine; 1,2-Diaminoethane; EDA; Ethane-1,2-diamine; Aethaldiamin; Aethylenediamin; 1,2-diaminoaethan; 1,2-Diamino-ethaan; 1, 2-Diamino-Ethano; Dimethylenediamine; Ethyleendiamine; Ethylene-diamine; β-Aminoethylamine CAS NO:107-15-3
ETHYLENEGLYCOL DIMETHACRYLATE
ETHYLHEXANOL, N° CAS : 104-76-7, Nom INCI : ETHYLHEXANOL, Nom chimique : 2-Ethylhexan-1-ol, N° EINECS/ELINCS : 203-234-3. Ses fonctions (INCI) : Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques. Noms français : 2-ETHYL HEXANOL; 2-ETHYL-1-HEXANOL; 2-Ethylhexyl alcohol; Alcool 2-éthylhexylique; Ethyl -2 hexanol;ETHYL-2 HEXANOL-1 ETHYLHEXANOL; Éthyl-2 hexanol; Noms anglais :2-Ethylhexanol; Utilisation et sources d'émission; Solvant de colorants, solvant de résines
ETHYLHEXANOIC ACID
Ethylhexanoic Acid is a colorless to light yellow liquid with a pungent odor.
Furthermore, Ethylhexanoic Acid is commonly used in the production of various chemicals, including plasticizers and lubricants.
Ethylhexanoic Acid can be harmful if ingested or inhaled, and proper safety precautions should be taken when handling it.


CAS Number: 2396-84-1
EC Number: 205-743-6
Chemical formula: C8H16O2
Molar mass: 144.214 g·mol−1
Appearance: Colorless liquid



APPLICATIONS


Ethylhexanoic Acid is used as a chemical intermediate for many products.
Moreover, Ethylhexanoic Acid is used in alkyd resins.

Ethylhexanoic Acid is used in the mid-1980s as a wood preservative to replace chlorophenols.
Further, Ethylhexanoic Acid is used to make plasticizers, lubricants, detergents, flotation aids, corrosion inhibitors, and alkyd resins.

Ethylhexanoic Acid is also used as a co-solvent and defoamer in pesticides, as the active ingredient in the wood preservative Sinesto B (not used in the US), in paint dryers, heat stabilizers for PVC, and as a catalyst for polyurethane foaming, solvent extraction, and dye granulation.
What is more, Ethylhexanoic Acid is not found in any pesticide products registered in the US.


Industry uses of Ethylhexanoic Acid:

Anti-adhesive agents
Corrosion inhibitor
Corrosion inhibitors and anti-scaling agents
Intermediate
Intermediates
Lubricants and lubricant additives
Lubricating agent
Not Known or Reasonably Ascertainable
Other
Other (specify)
Paint additives and coating additives not described by other categories
Process regulators
Processing aids, not otherwise listed
Propellants and blowing agents
Solvent


Ethylhexanoic Acid is used in the production of plasticizers to improve the flexibility and durability of plastics.
Furthermore, Ethylhexanoic Acid is a building block in the production of coatings, such as resins and polyurethanes.

Ethylhexanoic Acid is used in metalworking fluids to cool and lubricate metalworking machines.
Moreover, Ethylhexanoic Acid is used in the production of lubricants to reduce friction and wear between two surfaces.
Ethylhexanoic Acid is a raw material in the production of pharmaceuticals, such as antibiotics and anti-inflammatory drugs.

Ethylhexanoic Acid is used in the production of various chemical intermediates for further processing.
Besides, Ethylhexanoic Acid is used in the production of heat stabilizers for PVC applications.

Ethylhexanoic Acid is used in the production of fuel additives to improve fuel efficiency and reduce emissions.
In addition, Ethylhexanoic Acid is used as a precursor in the synthesis of various catalysts to speed up chemical reactions.

Ethylhexanoic Acid is used as a solvent in the production of various chemicals and materials.
More to that, Ethylhexanoic Acid is used in the production of agrochemicals, such as herbicides, fungicides, and insecticides, to protect crops from pests and diseases.


Here are some additional applications of Ethylhexanoic Acid:

Paint driers:

Ethylhexanoic Acid is used as a paint drier, which accelerates the drying process of paints and varnishes.

Adhesives:

Ethylhexanoic Acid is used as a raw material in the production of various adhesives, such as pressure-sensitive adhesives and hot-melt adhesives.

Corrosion inhibitors:

Ethylhexanoic Acid is used as a component in the formulation of corrosion inhibitors, which protect metals from corrosion.

Resin additives:

Ethylhexanoic Acid is used as a resin additive in the production of polyester and alkyd resins, which find use in coatings, adhesives, and plastics.

Surfactants:

Ethylhexanoic Acid is used in the production of surfactants, which are used to modify the surface tension of liquids, thereby improving their wetting and spreading properties.

Fragrances:

Ethylhexanoic Acid is used as a fragrance ingredient in the production of perfumes and other scented products.

Textile auxiliaries:

Ethylhexanoic Acid is used in the production of textile auxiliaries, which are used to enhance the performance of textile products, such as dyes, finishes, and coatings.

Metal salts:

Ethylhexanoic Acid is used to produce metal salts, which find use in various applications, such as inks, pigments, and catalysts.

Rubber additives:

Ethylhexanoic Acid is used as a rubber additive in the production of synthetic rubbers, which find use in various products, such as tires, hoses, and seals.

Plasticizers:

Ethylhexanoic Acid is a key component in the production of phthalate-free plasticizers, which are used in the production of food packaging materials and medical devices.

Coatings:

Ethylhexanoic Acid is used as a reactant in the production of acrylic resins, which find use in the production of paints, coatings, and adhesives.

Metalworking fluids:

Ethylhexanoic Acid is a common component in metalworking fluids due to its excellent lubricity and cooling properties.

Lubricants:

Ethylhexanoic Acid is used as a metal deactivator in lubricants to prevent oxidation and improve their performance at high temperatures.

Pharmaceuticals:

Ethylhexanoic Acid is used as a chiral building block in the synthesis of various drugs, such as the anti-inflammatory drug Naproxen.

Chemical intermediates:

Ethylhexanoic Acid is used as a key intermediate in the synthesis of various chemicals, such as fragrances, flavors, and surfactants.

Heat stabilizers:

Ethylhexanoic Acid is used in the production of heat stabilizers for PVC applications to prevent degradation and extend the lifespan of the material.

Fuel additives:

Ethylhexanoic Acid is used as a component in the production of fuel additives, such as octane boosters, which improve the performance and efficiency of gasoline engines.

Catalysts:

Ethylhexanoic Acid is used as a precursor in the synthesis of various catalysts, such as tin and zinc carboxylates, which find use in various chemical reactions.

Solvents:

Ethylhexanoic Acid is used as a solvent in the production of various chemicals, such as resins, coatings, and adhesives.

Agrochemicals:

Ethylhexanoic Acid is used as a key component in the production of herbicides, fungicides, and insecticides to protect crops from pests and diseases.


Overall, Ethylhexanoic Acid is a versatile chemical that finds use in various applications across different industries, thanks to its unique properties and versatility.


Ethylhexanoic Acid is not commonly used in consumer products, as it is primarily an industrial chemical with a wide range of industrial applications.
However, Ethylhexanoic Acid may be used as a raw material in the production of certain consumer products, such as coatings, adhesives, and plastics.

Additionally, some niche applications, such as the use of Ethylhexanoic Acid as a component in certain fragrances, may have consumer uses.
Overall, the use of Ethylhexanoic Acid is more common in industrial and commercial settings rather than in consumer products.


Ethylhexanoic Acid has various industrial applications, such as:

Coolant in automotives
Synthetic lubricant
Wetting agent
Co-solvent
Drying of paints
Defoaming agent in pesticides


Ethylhexanoic Acid is used as a synthetic lubricant due to its ability to reduce friction and wear between moving parts.
Further to that, Ethylhexanoic Acid is commonly used as a drying agent in paints and coatings to accelerate the drying process and improve film formation.

As a coolant in automotive applications, Ethylhexanoic Acid helps dissipate heat and prevent engine damage from overheating.
Ethylhexanoic Acid is utilized as a defoaming agent in pesticides to reduce foam formation during application and improve effectiveness.

In metalworking, Ethylhexanoic Acid is used as a corrosion inhibitor to protect against rust and other forms of corrosion.
Ethylhexanoic Acid is used as a wetting agent to reduce the surface tension of liquids and improve their ability to spread and penetrate surfaces.



DESCRIPTION


Ethylhexanoic acid is the organic compound with the formula CH3(CH2)3CH(C2H5)CO2H.
Furthermore, Ethylhexanoic acid is a carboxylic acid that is widely used to prepare lipophilic metal derivatives that are soluble in nonpolar organic solvents.

Ethylhexanoic acid is a colorless viscous oil.
More to that, Ethylhexanoic acid is supplied as a racemic mixture.
2-Ethylhexanoic acid is a branched-chain fatty acid.

Ethylhexanoic Acid is a colorless liquid with a pungent odor.
Thus, Ethylhexanoic Acid is soluble in alcohol, acetone, and ether.

Ethylhexanoic Acid is a carboxylic acid with the chemical formula C8H16O2.
Moreover, Ethylhexanoic Acid is a colorless liquid with a rancid odor and is soluble in water, ethanol, and ether.
It is also known as 2-ethylhexanoic acid or 2-EHA.

Ethylhexanoic Acid is primarily used as a raw material for the production of various chemicals and materials such as synthetic lubricants, plasticizers, and coatings.
Further, Ethylhexanoic Acid also has applications in the pharmaceutical and food industries.

Ethylhexanoic acid is a natural product found in Vitis vinifera and Artemisia arborescens with data available.
What is more, Ethylhexanoic Acid is a colorless liquid with a pungent odor.
Ethylhexanoic Acid is a carboxylic acid that belongs to the family of fatty acids.

Ethylhexanoic Acid is soluble in water, alcohol, and ether.
Further to that, Ethylhexanoic Acid has a wide range of industrial applications.

Ethylhexanoic Acid is used as a synthetic lubricant and as a drying agent in paints.
In addition, Ethylhexanoic Acid is also used as a coolant in automotive applications and as a defoaming agent in pesticides.

Ethylhexanoic Acid is produced through the oxidation of octanol or via the hydroformylation of butadiene.
Moreover, Ethylhexanoic Acid is also found naturally in human sweat and in breast milk.



PROPERTIES


Molecular Weight: 144.21
XLogP3: 2.6
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 5
Exact Mass: 144.115029749
Monoisotopic Mass: 144.115029749
Topological Polar Surface Area: 37.3 Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 99.4
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Boiling point: 226 - 229 °C (1013 hPa)
Density: 0.91 g/cm3 (20 °C)
Explosion limit: 0.9 - 6.7 %(V)
Flash point: 114 °C
Ignition temperature: 310 °C
Melting Point: -59 °C
pH value: 3 (1.4 g/l, H₂O, 20 °C)
Vapor pressure: Solubility: 1.4 g/l



FIRST AID


Skin Contact:

If Ethylhexanoic Acid comes into contact with skin, immediately remove any contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes.
Seek medical attention if skin irritation, redness, or pain persists.


Eye Contact:

If Ethylhexanoic Acid comes into contact with eyes, flush the affected eye with water for at least 15 minutes, lifting the upper and lower eyelids occasionally.
Seek medical attention immediately.


Inhalation:

If Ethylhexanoic Acid is inhaled, remove the affected person to fresh air immediately.
If the person is not breathing, administer artificial respiration.
Seek medical attention if the person experiences difficulty breathing, coughing, or wheezing.


Ingestion:

If Ethylhexanoic Acid is ingested, do not induce vomiting.
Rinse the mouth with water and drink plenty of water to dilute the acid.
Seek medical attention immediately.


Personal Protective Equipment:

Always wear personal protective equipment when handling Ethylhexanoic Acid, including gloves, goggles, and a lab coat or protective clothing.


Spill Response:

In the event of a spill, isolate the area and keep unauthorized personnel away.
Wear personal protective equipment and contain the spill with an absorbent material.
Collect the contaminated material and dispose of it according to local regulations.


It is important to note that Ethylhexanoic Acid can cause severe skin and eye irritation, and may be harmful if inhaled or ingested.
Seek immediate medical attention if exposure occurs.



HANDLING AND STORAGE


Ethylhexanoic Acid should be stored in a cool, dry, well-ventilated area, away from direct sunlight and sources of heat or ignition.
Further, Ethylhexanoic Acid should be kept in a tightly sealed container and handled only in a fume hood or with appropriate personal protective equipment.
Ethylhexanoic Acid should be stored separately from incompatible materials such as strong oxidizers, acids, and bases.

Containers of Ethylhexanoic Acid should be labeled with the appropriate hazard warnings and handling instructions.
When handling Ethylhexanoic Acid, appropriate personal protective equipment should be worn, including gloves, safety goggles, and a lab coat or apron.

In case of skin or eye contact, immediately flush the affected area with plenty of water for at least 15 minutes and seek medical attention.
If Ethylhexanoic Acid is ingested, do not induce vomiting and seek medical attention immediately.

Spills of Ethylhexanoic Acid should be cleaned up immediately using absorbent materials and appropriate protective equipment.
Disposal of Ethylhexanoic Acid should be done in accordance with local, state, and federal regulations, and should not be disposed of in regular trash or down the drain.

Ethylhexanoic Acid should be kept away from children and unauthorized personnel, and should only be handled by trained professionals who are familiar with the hazards and proper handling procedures.



SYNONYMS


2-ETHYLHEXANOIC ACID
149-57-5
2-Ethylcaproic acid
Hexanoic acid, 2-ethyl-
Ethylhexanoic acid
Ethylhexoic acid
2-Ethylhexoic acid
Butylethylacetic acid
2-Butylbutanoic acid
3-Heptanecarboxylic acid
Ethyl hexanoic acid
2-ethyl-hexoic acid
2-ethyl hexanoic acid
alpha-Ethylcaproic acid
2-ethyl-hexanoic acid
Ethyl hexanoic acid, 2-
2 ETHYL HEXANOIC ACID
alpha-ethyl caproic acid
.alpha.-Ethylcaproic acid
2-Ethyl-1-hexanoic acid
(+/-)-2-ETHYLHEXANOIC ACID
01MU2J7VVZ
2-ETHYL HEXOIC ACID,AR
61788-37-2
CHEBI:89058
NSC-8881
2-ethylhexanoicacid
2-Ethylhexansaeure
2-Ethylhexanoic acid, >=99%
2-Ethylhexanoic acid, analytical standard
CAS-149-57-5
CCRIS 3348
HSDB 5649
Kyselina 2-ethylkapronova [Czech]
NSC 8881
Kyselina 2-ethylkapronova
EINECS 205-743-6
UNII-01MU2J7VVZ
Kyselina heptan-3-karboxylova [Czech]
BRN 1750468
Kyselina heptan-3-karboxylova
AI3-01371
Hexanoic acid, 2-ethyl-, (-)-
EINECS 262-971-9
MFCD00002675
2-Ethylcapronic acid
2-Ethyl-Hexonic acid
alpha-Ethylhexanoic acid
.alpha.-Ethylhexanoic acid
EC 205-743-6
SCHEMBL25800
2-Ethylhexanoic acid, 99%
MLS002415695
CHEMBL1162485
DTXSID9025293
WLN: QVY4 & 2
NSC8881
HMS2267F21
STR05759
2-ETHYLHEXANOIC ACID [HSDB]
Tox21_201406
Tox21_300108
LMFA01020087
AKOS009031416
AT29893
CS-W016381
SB44987
SB44994
Hexanoic acid,2-ethyl-, tridecyl ester
NCGC00091324-01
NCGC00091324-02
NCGC00091324-03
NCGC00253985-01
NCGC00258957-01
SMR001252268
E0120
2-Ethylhexanoic Acid
2-Ethylcaproic Acid
Isooctanoic Acid
Octanoic Acid, 2-ethyl-
2-ethylhexoic acid
Ethylhexoic Acid
FT-0612273
FT-0654390
EN300-20410
Q209384
W-109079
F0001-0703
Z104478072
18FEB650-7573-4EA0-B0CD-9D8BED766547
2-Ethylhexanoic acid, Pharmaceutical Secondary Standard; Certified Reference Material
ETHYLHEXANOL ( Alcool 2-éthylhexylique)
ETHYLHEXYL ACRYLATE, N° CAS : 103-11-7, Nom INCI : ETHYLHEXYL ACRYLATE. N° EINECS/ELINCS : 203-080-7. Ses fonctions (INCI) : Agent fixant : Permet la cohésion de différents ingrédients cosmétiques. Noms français : 2-ETHYLHEXYL-2-PROPENOATE 2-PROPENOIC ACID, 2-ETHYLHEXYL ESTER Acrylate d'éthyl-2 hexyle PROPENOATE-2 D'ETHYL-2 HEXYLE Noms anglais : 2-Ethylhexyl acrylate ACRYLIC ACID 2-ETHYLHEXYL ESTER ACRYLIC ACID, 2-ETHYLHEXYL ESTER ETHYLHEXYL-2 ACRYLATE Utilisation et sources d'émission Fabrication de polymères
ETHYLHEXYL ACRYLATE ( Acrylate d'éthyl-2 hexyle)
ETHYLHEXYL BENZOATE, N° CAS : 5444-75-7. Nom INCI : ETHYLHEXYL BENZOATE. Nom chimique : 2-Ethylhexyl benzoate. N° EINECS/ELINCS : 226-641-8. Ses fonctions (INCI): Emollient : Adoucit et assouplit la peau. Agent d'entretien de la peau : Maintient la peau en bon état. Solvant : Dissout d'autres substances. 226-641-8 [EINECS] 2-Ethylhexyl benzoate 2-Ethylhexyl-benzoat [German] 4Y2&1OVR [WLN] 5444-75-7 [RN] Benzoate de 2-éthylhexyle [French] Benzoic acid, 2-ethylhexyl ester [ACD/Index Name] MFCD00072620 [MDL number] [5444-75-7] 2-Ethylhexylbenzoate benzoic acid 2-ethyl-hexyl ester BENZOICACID2-ETHYLHEXYLESTER Ethylhexyl benzoate PI-46931 Velate 368
Ethylhexyl benzoate ( Benzoate de 2-éthylhexyle)
ETHYLHEXYL COCOATE, N° CAS : 92044-87-6. Nom INCI : ETHYLHEXYL COCOATE. N° EINECS/ELINCS : 295-366-3. Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau
ETHYLHEXYL COCOATE
ETHYLHEXYL DIMETHYL PABA. N° CAS : 21245-02-3. Nom INCI : ETHYLHEXYL DIMETHYL PABA, Nom chimique : 2-Ethylhexyl 4-(dimethylamino)benzoate. N° EINECS/ELINCS : 244-289-3, Classification : Filtre UV Chimique, Règlementé. La concentration maximale autorisée en cosmétique est la suivante : 8 %.. Ses fonctions (INCI) : Absorbant UV : Protège le produit cosmétique contre les effets de la lumière UV. Filtre UV : Permet de filtrer certains rayons UV afin de protéger la peau ou les cheveux des effets nocifs de ces rayons.Noms français : OCTYL DIMETHYL PABA Noms anglais : 2-ETHYLHEXYL P-DIMETHYLAMINOBENZOATE; BENZOIC ACID, 4-(DIMETHYLAMINO)-, 2-ETHYLHEXYL ESTER
ETHYLHEXYL COCOATE


Ethylhexyl Cocoate, also known as Octyl Cocoate, is an ester compound formed by the reaction of ethylhexanol (2-ethylhexanol) with fatty acids derived from coconut oil.
Ethylhexyl Cocoate is commonly used in cosmetics, personal care products, and industrial applications as an emollient, moisturizer, and texturizer due to its lightweight and non-greasy properties.
Ethylhexyl Cocoate is valued for its ability to improve the spreadability of formulations, provide a smooth skin feel, and contribute to a luxurious sensory experience.

CAS Number: 65381-09-1
EC Number: 265-499-7



APPLICATIONS


Ethylhexyl Cocoate is extensively used in cosmetic and personal care products for its versatile properties.
Ethylhexyl Cocoate finds application in body lotions, contributing to their lightweight texture and moisturizing effects.

In facial moisturizers, Ethylhexyl Cocoate helps maintain the skin's hydration without a greasy residue.
Ethylhexyl Cocoate is a common ingredient in sunscreens, aiding in the dispersion of UV filters and enhancing product efficacy.
Ethylhexyl Cocoate improves the spreadability of makeup products, ensuring smooth and even application.
Ethylhexyl Cocoate is utilized in lip balms, providing a non-sticky texture and offering moisturizing benefits.

Ethylhexyl Cocoate contributes to hair care products such as conditioners, enhancing hair shine and manageability.
Ethylhexyl Cocoate is included in shower gels and body washes to provide a silky and luxurious feel on the skin.

Ethylhexyl Cocoate is employed in after-shave lotions and balms to soothe the skin while adding a non-greasy finish.
Ethylhexyl Cocoate plays a role in foundation formulations, helping to create a seamless and natural-looking complexion.
Ethylhexyl Cocoate is used in baby care products, ensuring gentle hydration and comfort for delicate skin.
Ethylhexyl Cocoate contributes to serums, aiding the even distribution of active ingredients for targeted skincare benefits.
In hand creams, Ethylhexyl Cocoate prevents dryness and promotes soft, supple hands.

Ethylhexyl Cocoate is found in anti-aging products, contributing to improved skin texture and moisture retention.
Ethylhexyl Cocoate enhances the solubility of lipophilic actives in skincare formulations.
Ethylhexyl Cocoate is incorporated in body oils, providing a luxurious, non-greasy feel while deeply moisturizing the skin.

Ethylhexyl Cocoate plays a role in BB creams and tinted moisturizers, offering both coverage and hydration.
Ethylhexyl Cocoate contributes to massage oils, allowing for a smooth glide and comfortable application.
Ethylhexyl Cocoate is used in natural and organic product formulations, appealing to consumers seeking clean beauty options.
Ethylhexyl Cocoate finds application in post-workout skincare, soothing the skin after physical activity.

Ethylhexyl Cocoate is utilized in pre-tanning oils, preparing the skin for sun exposure while maintaining hydration.
Ethylhexyl Cocoate enhances the stability of formulations, helping prevent ingredient separation and prolonging shelf life.

Ethylhexyl Cocoate is employed in therapeutic creams and ointments due to its non-irritating and moisturizing properties.
Ethylhexyl Cocoate aligns with the formulation of matte-finish and oil-free cosmetics for a non-greasy look.
Ethylhexyl Cocoate is recognized for its ability to create a protective barrier on the skin, making it a valuable ingredient in various skincare and cosmetic products.
Ethylhexyl Cocoate is an essential ingredient in body butters and creams, contributing to their rich and moisturizing texture.
Ethylhexyl Cocoate finds use in facial cleansing oils, effectively removing makeup and impurities while leaving the skin soft.

Ethylhexyl Cocoate is added to primer formulations, creating a smooth canvas for makeup application.
Ethylhexyl Cocoate is incorporated into lip glosses and lipsticks, providing a comfortable and hydrating feel on the lips.
Ethylhexyl Cocoate is used in cosmetic products with anti-inflammatory properties, assisting in calming and soothing the skin.
Ethylhexyl Cocoate is employed in cuticle oils, softening and nourishing the cuticles for healthier nails.

Ethylhexyl Cocoate is included in hair styling products like serums and sprays, reducing frizz and adding shine.
Ethylhexyl Cocoate is utilized in body scrubs, enhancing their application and promoting soft and rejuvenated skin.
Ethylhexyl Cocoate contributes to foot creams, aiding in the prevention of dry and cracked heels.
Ethylhexyl Cocoate is found in men's grooming products, offering moisturization and a comfortable shave.

Ethylhexyl Cocoate is used in makeup removers, efficiently dissolving makeup without leaving an oily residue.
Ethylhexyl Cocoate is added to body mists, providing a refreshing and non-sticky sensation on the skin.
Ethylhexyl Cocoate is utilized in under-eye creams, helping to minimize dryness and fine lines.
Ethylhexyl Cocoate is employed in body powders, enhancing their texture and providing a silky application.
Ethylhexyl Cocoate contributes to hair conditioners, improving manageability and promoting a healthy appearance.

Ethylhexyl Cocoate is found in natural deodorants, helping to maintain skin comfort throughout the day.
Ethylhexyl Cocoate is used in cooling and soothing gels for after-sun care, offering relief to sun-exposed skin.
Ethylhexyl Cocoate is added to massage creams, ensuring a smooth and enjoyable massage experience.
Ethylhexyl Cocoate is utilized in self-tanning products, aiding in even color application and prolonging tan appearance.

Ethylhexyl Cocoate is included in post-procedure skincare, providing gentle hydration and aiding in skin recovery.
Ethylhexyl Cocoate contributes to body lotions with aromatic blends, offering a pleasant scent along with moisturization.
Ethylhexyl Cocoate is used in cosmetic products targeted at sensitive or reactive skin, providing a soothing touch.

Ethylhexyl Cocoate is employed in hand sanitizers, preventing skin dryness caused by frequent use.
Ethylhexyl Cocoate is added to body creams with a quick-absorbing formula, leaving no sticky residue.
Ethylhexyl Cocoate's role in formulations extends to luxury skincare, enhancing the overall sensorial experience of high-end products.

Ethylhexyl Cocoate is a key ingredient in tinted moisturizers, providing hydration and a hint of color for a natural look.
Ethylhexyl Cocoate is used in post-shave products, soothing and moisturizing the skin after shaving.
Ethylhexyl Cocoate is added to body creams with fast-absorbing properties, allowing for quick dressing after application.
Ethylhexyl Cocoate finds use in shaving creams, aiding in the smooth gliding of razors and minimizing irritation.

Ethylhexyl Cocoate contributes to hand lotions, maintaining softness and comfort even with frequent hand washing.
Ethylhexyl Cocoate is employed in anti-itch creams, providing relief to irritated and sensitive skin.
Ethylhexyl Cocoate is utilized in facial masks, helping to improve the spreadability and adherence of mask formulations.

Ethylhexyl Cocoate is included in facial mists, offering a burst of hydration and refreshment throughout the day.
Ethylhexyl Cocoate finds application in cooling gels for sore muscles, providing comfort and relaxation.
Ethylhexyl Cocoate is added to body oils, enhancing their ability to deeply moisturize and nourish the skin.

Ethylhexyl Cocoate is used in men's grooming products such as beard oils, promoting a well-groomed appearance.
Ethylhexyl Cocoate contributes to lip balms with SPF protection, combining hydration and sun protection.
Ethylhexyl Cocoate is utilized in dry shampoo formulations, aiding in the absorption of excess oils.
Ethylhexyl Cocoate is included in body firming creams, contributing to smoother and more toned skin.

Ethylhexyl Cocoate finds use in foot scrubs, enhancing their exfoliating and rejuvenating effects.
Ethylhexyl Cocoate is added to bath oils, providing a luxurious and moisturizing bathing experience.
Ethylhexyl Cocoate is employed in natural deodorant sticks, ensuring comfortable and effective odor protection.
Ethylhexyl Cocoate contributes to body washes with creamy textures, leaving the skin feeling soft and nourished.

Ethylhexyl Cocoate is used in pre-makeup primers, creating a smooth and hydrated canvas for makeup application.
Ethylhexyl Cocoate is included in body serums, offering concentrated hydration and nutrients to the skin.
Ethylhexyl Cocoate finds application in cuticle creams, promoting healthy and conditioned cuticles.
Ethylhexyl Cocoate is utilized in cosmetic products with soothing effects on irritated skin, such as post-exfoliation treatments.

Ethylhexyl Cocoate is added to body balms, providing intensive hydration and protection for dry skin areas.
Ethylhexyl Cocoate contributes to makeup setting sprays, helping to lock in makeup while providing a refreshing mist.
Ethylhexyl Cocoate is found in multi-purpose products like all-in-one creams, offering a range of benefits in a single formulation.

Ethylhexyl Cocoate is incorporated into body lotions for its ability to create a lightweight, non-greasy formula that leaves the skin soft and smooth.
Ethylhexyl Cocoate finds use in facial serums, helping to improve the skin's texture and providing a youthful appearance.

Ethylhexyl Cocoate is added to hand creams, protecting the skin from dryness and environmental stressors.
Ethylhexyl Cocoate is utilized in body washes and shower gels, contributing to their creamy lather and moisturizing properties.
Ethylhexyl Cocoate is included in facial cleansers, aiding in the gentle removal of impurities without stripping the skin's natural oils.
Ethylhexyl Cocoate is employed in lip care products, such as lip scrubs, offering exfoliation and hydration.

Ethylhexyl Cocoate finds application in soothing creams for skin conditions like eczema, providing relief and comfort.
Ethylhexyl Cocoate contributes to massage oils, enhancing the glide and promoting relaxation during massages.
Ethylhexyl Cocoate is added to foot scrubs, revitalizing tired feet and helping to remove dead skin cells.
Ethylhexyl Cocoate is utilized in beard balms, taming and nourishing facial hair for a well-groomed appearance.

Ethylhexyl Cocoate is found in makeup remover wipes, effectively dissolving makeup and impurities while maintaining skin hydration.
Ethylhexyl Cocoate is employed in bath bombs, infusing the water with moisturizing and skin-soothing properties.

Ethylhexyl Cocoate contributes to natural sunscreens, aiding in the dispersion of mineral sunscreens and providing hydration.
Ethylhexyl Cocoate is included in hair masks, adding moisture and shine to dry or damaged hair.
Ethylhexyl Cocoate is added to foundation formulations, enhancing the blendability and natural finish of the product.

Ethylhexyl Cocoate is utilized in lip care products like lip masks, providing deep hydration and softness.
Ethylhexyl Cocoate is employed in cuticle balms, promoting healthy nails and cuticles.
Ethylhexyl Cocoate finds use in makeup setting powders, preventing cakiness and maintaining a fresh makeup look.

Ethylhexyl Cocoate is added to body exfoliators, helping to polish the skin's surface and leave it feeling renewed.
Ethylhexyl Cocoate is found in soothing aftersun gels, providing relief to sunburned or irritated skin.

Ethylhexyl Cocoate is utilized in priming sprays, creating a hydrated and even canvas for makeup application.
Ethylhexyl Cocoate is included in hair serums, taming frizz and adding a healthy shine to the hair.

Ethylhexyl Cocoate is employed in foot creams, aiding in the prevention of dry, cracked heels.
Ethylhexyl Cocoate contributes to makeup cushion compacts, offering foundation with added skincare benefits.
Ethylhexyl Cocoate finds application in fragrance-free skincare products, appealing to individuals with sensitive skin or fragrance allergies.



DESCRIPTION


Ethylhexyl Cocoate, also known as Octyl Cocoate, is an ester compound formed by the reaction of ethylhexanol (2-ethylhexanol) with fatty acids derived from coconut oil.
Ethylhexyl Cocoate is commonly used in cosmetics, personal care products, and industrial applications as an emollient, moisturizer, and texturizer due to its lightweight and non-greasy properties.
Ethylhexyl Cocoate is valued for its ability to improve the spreadability of formulations, provide a smooth skin feel, and contribute to a luxurious sensory experience.

In cosmetics and skincare, Ethylhexyl Cocoate is often incorporated into various products such as lotions, creams, sunscreens, makeup products, and hair care items.
Its versatile properties make it suitable for formulations targeting different skin types and preferences.
As an emollient, Ethylhexyl Cocoate helps to lock in moisture, leaving the skin soft and hydrated.
Its non-comedogenic nature makes it suitable for facial products as well.

Ethylhexyl Cocoate is a versatile and widely used ester compound derived from the reaction of ethylhexanol and coconut oil fatty acids.
Ethylhexyl Cocoate is valued for its ability to enhance the sensory experience of cosmetic and personal care products.

With a clear to slightly yellowish appearance, Ethylhexyl Cocoate boasts a lightweight texture that is non-greasy on the skin.
Known for its emollient properties, it effectively locks in moisture, leaving the skin feeling soft and hydrated.
Ethylhexyl Cocoate is often selected for formulations targeting various skin types due to its compatibility with sensitive and acne-prone skin.

Ethylhexyl Cocoate finds its place in lotions, creams, sunscreens, and makeup products, contributing to their smooth application and skin-feel.
As a texture enhancer, Ethylhexyl Cocoate aids in the even spreadability of products, enhancing the overall application experience.
The chemical aligns with clean beauty principles and natural formulations, fitting well into environmentally conscious cosmetic products.

Ethylhexyl Cocoate is known for its biodegradability and relatively low toxicity, making it an eco-friendly choice.
Ethylhexyl Cocoate is particularly useful in formulations where a non-comedogenic ingredient is desirable, making it suitable for facial skincare products.
Its ability to create a protective barrier on the skin contributes to its inclusion in moisturizers and creams.

Ethylhexyl Cocoate's compatibility with a wide range of other ingredients allows for versatile formulations across the cosmetics industry.
In sunscreens, Ethylhexyl Cocoate helps to disperse UV filters evenly, improving the product's overall efficacy.
Ethylhexyl Cocoate plays a role in maintaining hair health by adding shine and smoothness to hair care formulations.

Ethylhexyl Cocoate's non-greasy texture makes it a preferred choice for oil-free or matte-finish cosmetic products.
Ethylhexyl Cocoate has the capacity to enhance the solubility of lipophilic (fat-soluble) active ingredients in formulations.
Ethylhexyl Cocoate is recognized for its role in providing a luxurious sensory experience, making products more enjoyable to use.
Its versatility extends to industrial applications, where it is used in lubricants and metalworking fluids for its lubricating properties.

Ethylhexyl Cocoate contributes to the stability of formulations, helping to prevent the separation of ingredients.
Ethylhexyl Cocoate aligns with the trend towards multifunctional products, as Ethylhexyl Cocoate can simultaneously moisturize and improve texture.
Ethylhexyl Cocoate is included in some pharmaceutical formulations and therapeutic creams due to its gentle and hydrating nature.

Ethylhexyl Cocoate's mild and pleasant odor makes it suitable for products with added fragrances or scents.
Its compatibility with various skin types extends its use to baby care products and products for sensitive skin.
Ethylhexyl Cocoate is preferred in natural and organic product formulations, appealing to consumers seeking cleaner ingredients.
Ethylhexyl Cocoate's non-sensitizing properties, along with its moisturizing benefits, make it a valuable ingredient in modern cosmetics.



PROPERTIES


Chemical Formula: C26H50O3
Molecular Weight: Approximately 410.68 g/mol
Appearance: Clear to slightly yellowish liquid
Odor: Characteristic odor
Texture: Lightweight and non-greasy
Solubility: Soluble in oils and organic solvents
Melting Point: Approximately -4°C to -3°C (25°F to 27°F)
Boiling Point: Varies with composition, typically around 200°C (392°F)
Flash Point: Varies with composition, typically above 100°C (212°F)
Density: Approximately 0.9 - 0.95 g/cm³
Viscosity: Low to moderate viscosity depending on formulation and temperature
pH: Neutral to slightly acidic
Compatibility: Compatible with a wide range of cosmetic ingredients



FIRST AID


Inhalation:
If inhaled, move the person to fresh air.
If breathing is difficult, provide oxygen and seek medical attention.

Skin Contact:
In case of skin contact, immediately remove contaminated clothing and wash the affected area with plenty of soap and water.
If irritation persists, seek medical attention.
Wash contaminated clothing before reusing.

Eye Contact:
If Ethylhexyl Cocoate comes into contact with the eyes, immediately rinse them gently with water for several minutes, keeping eyelids open.
Remove contact lenses if present and easy to do so.
Seek medical attention if irritation or discomfort persists.

Ingestion:
If accidentally swallowed, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth with water and seek medical attention.
Do not give anything by mouth to an unconscious person.



HANDLING AND STORAGE


Handling:

Ventilation:
Ensure proper ventilation in the work area to prevent the accumulation of vapors or fumes.

Personal Protective Equipment (PPE):
Wear appropriate protective clothing, including gloves and safety goggles, when handling Ethylhexyl Cocoate to prevent skin and eye contact.

Avoid Contact:
Avoid direct contact with skin, eyes, and clothing.
In case of accidental contact, follow the recommended first aid measures and wash affected areas thoroughly with water and soap.

No Smoking:
Do not smoke, eat, or drink while handling the substance to prevent accidental ingestion.

Storage:
Store Ethylhexyl Cocoate away from incompatible materials, such as strong oxidizing agents, acids, and bases.

Spill Control:
Have spill containment measures in place to prevent leaks and spills from spreading. Use absorbent materials to clean up small spills.

Static Electricity:
Ground containers during transfer to prevent the buildup of static electricity, which could result in sparks.


Storage:

Location:
Store Ethylhexyl Cocoate in a cool, dry, well-ventilated area, away from direct sunlight and heat sources.

Temperature:
Maintain storage temperatures within the recommended range to prevent degradation or changes in physical properties.

Containers:
Keep the substance in tightly closed containers made of suitable materials to prevent leakage and contamination.

Compatibility:
Store Ethylhexyl Cocoate away from incompatible materials, such as strong acids, strong bases, and strong oxidizers.

Labeling:
Ensure containers are properly labeled with the substance's name, hazards, and handling instructions.

Segregation:
Store Ethylhexyl Cocoate away from food, beverages, and medical supplies to prevent accidental ingestion.

Fire Safety:
Store away from open flames, sparks, and ignition sources, as the substance may have a flash point above 100°C (212°F).



SYNONYMS


Coco-Caprylate/Caprate
Ethylhexyl Ester of Coconut Fatty Acid
Ethylhexyl Ester of Coco Fatty Acid
Ethylhexyl Coconutate
Ethylhexyl Cocoglyceride
Ethylhexyl Cocoate Ester
Coconut Oil Ethyl Ester
Coco Fatty Acid Ethyl Ester
Ethylhexyl Coconut Oil Ester
Octyl Cocoate
Coconut Acid Ethyl Ester
Coco Alkyl Ester
Ethylhexyl Esters of Coconut Oil
Ester of Coconut Oil Fatty Acid and 2-Ethylhexanol
Ethylhexyl Cocoate Ester
Ester of Coco Fatty Acid and Ethylhexanol
Ethylhexyl Coco Fatty Acid Ester
Coco Fatty Acid Octyl Ester
Ethylhexyl Ester of Coconut Fatty Acid
Ester of Coconut Acid and Ethylhexyl Alcohol
Ethylhexyl Cocoglycinate
Ethylhexyl Ester of Coco Acid
Coconut Fatty Acid Octyl Ester
Octyl Ester of Coco Fatty Acid
Ethylhexyl Coconutate
Coco Ester Ethylhexyl
Ethylhexyl Coconut Fatty Acid Ester
Octyl Ester of Coconut Acid
Ethylhexyl Ester of Coco Fatty Acid
Coco Acid Ethyl Ester
Ethylhexyl Ester of Coconut Acid
Coco Fatty Acid Ethylhexyl Ester
Ethylhexyl Cocoate Ester
Ester of Ethylhexyl Alcohol and Coconut Fatty Acid
Ethylhexyl Coconut Oil Ester
Ethylhexyl Ester of Coco Acid
Coco Acid Octyl Ester
Ethylhexyl Ester of Coconut Oil Fatty Acid
Ethylhexyl Cocoglycolate
Ethylhexyl Cocoate Ethyl Ester
Octyl Ester of Coco Fatty Acid
Ethylhexyl Esters of Coconut Acid
Coco Acid Ethylhexyl Esters
Ethylhexyl Ester of Coconut Acid
Ethylhexyl Coco Fatty Acid Octyl Ester
Ester of Ethylhexanol and Coconut Fatty Acid
Ethylhexyl Cocoate Ethylhexyl Ester
Ethylhexyl Ester of Coco Oil Fatty Acid
Ethylhexyl Cocoate Ethylhexyl Ester
Ester of Ethylhexanol and Coco Acid
Ethylhexyl Ester of Cocos Nucifera Oil Acid
Octyl Ester of Coconut Fatty Acid
Ethylhexyl Ester of Coco Acid and 2-Ethylhexanol
Ethylhexyl Coconutate Ester
Ethylhexyl Ester of Cocos Nucifera Acid
Ethylhexyl Coco Fatty Acid Ethyl Ester
Octyl Coconut Acid Ester
Ethylhexyl Ester of Cocos Nucifera Oil Fatty Acid
Ethylhexyl Cocoglycerides
Ethylhexyl Coconut Acid Ester
Octyl Esters of Coco Fatty Acid
Ethylhexyl Ester of Coconut Acid and Octyl Alcohol
Ethylhexyl Ester of Cocos Nucifera Acid
Ethylhexyl Coco Fatty Acid Cocoate
Ethylhexyl Ester of Cocos Nucifera Oil Fatty Acid
Ethylhexyl Cocoate of Coconut Acid
Octyl Cocoate of Coco Acid
Ethylhexyl Ester of Coconut Fatty Acid and Octyl Alcohol
Ethylhexyl Coco Fatty Acid Coconutate
Ethylhexyl Ester of Cocos Nucifera Oil Acid
Ethylhexyl Cocoate of Cocos Nucifera Acid
Octyl Ester of Cocos Nucifera Oil Acid
Ethylhexyl Ester of Cocos Nucifera Oil Fatty Acid
Octyl Ester of Cocos Nucifera Acid
Ethylhexyl Cocoate of Coconut Oil Fatty Acid
ETHYLHEXYL DIMETHYL PABA
ETHYLHEXYL DIMETHYL PABA Ethylhexyl Dimethyl PABA(Escalol 507). Escalol 507 UV filter by Ashland Specialty Chemical acts as a UV filter. It is a powerful oil-soluble UV-B absorber and offers protection against UV-B and UV-A radiation. It provides cost-effective performance and excellent safety profile. Escalol 507 UV filter finds application in formulating sun-care (after-sun, self-tanning and sunscreen application), body- & facial-care formulas and color cosmetics. Abstract Ethylhexyl Dimethyl PABA(Escalol 507)-aminobenzoic acid (PABA) is an oily yellow liquid derivative of water-soluble PABA commonly used in sunscreen. Ethylhexyl Dimethyl PABA(Escalol 507) is widely used as an ingredient in many cosmetics at an average concentration of 1.25% (0.5-2.0%) in Korea. Previous studies, including those involving animals, have demonstrated that Ethylhexyl Dimethyl PABA(Escalol 507) is toxic to the following four organs: testis, epididymis, spleen, and liver. In addition, experiments using human keratinocytes found that Ethylhexyl Dimethyl PABA(Escalol 507) inhibits cell growth and DNA synthesis at low concentrations, and halted the cell cycle of MM96L cells (human melanoma cell line) at the G1 phase. Despite limited clinical data in humans, many studies have confirmed increased mutagenicity of Ethylhexyl Dimethyl PABA(Escalol 507) following exposure to sunlight, which suggests that this molecule is likely to contribute to onset of sun-induced cancer despite protecting the skin through absorption of UVB. For risk assessment, the no observed adverse effect level (NOAEL) chosen was 100 mg/kg bw/day in a 4 weeks oral toxicity study. Systemic exposure dosage (SED) was 0.588 mg/kg bw/day for maximum use of Ethylhexyl Dimethyl PABA(Escalol 507) in cosmetics. Based on the risk assessment and exposure scenarios conducted in this study, the margin of safety (MOS) was calculated to be 180.18 for a sunscreen containing 8% Ethylhexyl Dimethyl PABA(Escalol 507), which is the maximum level allowed by the relevant domestic authorities. Ethylhexyl Dimethyl PABA(Escalol 507)-aminobenzoic acid (PABA) is an oily yellow liquid derivative of water-soluble PABA commonly used in sunscreen. Ethylhexyl Dimethyl PABA(Escalol 507) is widely used as an ingredient in many cosmetics at an average concentration of 1.25% (0.5-2.0%) in Korea. Previous studies, including those involving animals, have demonstrated that Ethylhexyl Dimethyl PABA(Escalol 507) is toxic to the following four organs: testis, epididymis, spleen, and liver. In addition, experiments using human keratinocytes found that Ethylhexyl Dimethyl PABA(Escalol 507) inhibits cell growth and DNA synthesis at low concentrations, and halted the cell cycle of MM96L cells (human melanoma cell line) at the G1 phase. Despite limited clinical data in humans, many studies have confirmed increased mutagenicity of Ethylhexyl Dimethyl PABA(Escalol 507) following exposure to sunlight, which suggests that this molecule is likely to contribute to onset of sun-induced cancer despite protecting the skin through absorption of UVB. For risk assessment, the no observed adverse effect level (NOAEL) chosen was 100 mg/kg bw/day in a 4 weeks oral toxicity study. Systemic exposure dosage (SED) was 0.588 mg/kg bw/day for maximum use of Ethylhexyl Dimethyl PABA(Escalol 507) in cosmetics. Based on the risk assessment and exposure scenarios conducted in this study, the margin of safety (MOS) was calculated to be 180.18 for a sunscreen containing 8% Ethylhexyl Dimethyl PABA(Escalol 507), which is the maximum level allowed by the relevant domestic authorities. Ethylhexyl Dimethyl PABA(Escalol 507) Ethylhexyl Dimethyl PABA(Escalol 507) is classified as : Uv absorber Uv filter CAS Number 21245-02-3 EINECS/ELINCS No: 244-289-3 Restriction (applies to EU only): VII/21 COSING REF No: 33875 INN Name: padimate-O Chem/IUPAC Name: 2-Ethylhexyl 4-(dimethylamino)benzoate Ethylhexyl Dimethyl PABA(Escalol 507) Icky ALSO-CALLED-LIKE-THIS: Padimate O, Octyl Dimethyl PABA, Eusolex 6007 WHAT-IT-DOES: sunscreen Official CosIng Information Details Ethylhexyl Dimethyl PABA(Escalol 507) is a chemical sunscreen agent that protects in the UVB range (290-320 nm) with a peak absorbance at 312nm. Other than that, we struggle to write anything positive about this guy, as it is photo unstable (looses 10% efficacy in 20 mins and 50% in 85 mins), not an unfrequent allergen in sunscreens and shows some endocrine effect in animal studies. All this does not mean that it is not considered safe as used, it is (and is approved up to 8% in the EU and US and up to 3% in Japan), but we do think that there are plenty of other and better UV filters out there. Ethylhexyl Dimethyl PABA(Escalol 507) Messages Overview(active tab) Safety Resources What Is It? Ethylhexyl Dimethyl PABA(Escalol 507) is a yellowish, oily liquid. In cosmetics and personal care products, Ethylhexyl Dimethyl PABA(Escalol 507) is used in the formulation of sunscreen products, shampoos, conditioners, hair sprays, makeup, and bath and skin products. When it is used in sunscreen drug products, Ethylhexyl Dimethyl PABA(Escalol 507) is called Padimate O. Why is it used in cosmetics and personal care products? Padimate O, when applied to the skin, absorbs UV rays. In addition to causing sunburn, UV radiation is a significant cause of premature aging of the skin and contributes to the development of melanoma and other forms of skin cancer. Ethylhexyl Dimethyl PABA(Escalol 507) can also be used to protect cosmetics and personal care products from deterioration by absorbing, UV rays Scientific Facts: Ethylhexyl Dimethyl PABA(Escalol 507), or Octyl Dimethyl para-Aminobenzoic Acid (PABA), absorbs ultraviolet radiation and converts it into less damaging infrared radiation (heat). Abstract Ethylhexyl Dimethyl PABA(Escalol 507)-aminobenzoic acid (PABA) is an oily yellow liquid derivative of water-soluble PABA commonly used in sunscreen. Ethylhexyl Dimethyl PABA(Escalol 507) is widely used as an ingredient in many cosmetics at an average concentration of 1.25% (0.5–2.0%) in Korea. Previous studies, including those involving animals, have demonstrated that Ethylhexyl Dimethyl PABA(Escalol 507) is toxic to the following four organs: testis, epididymis, spleen, and liver. In addition, experiments using human keratinocytes found that Ethylhexyl Dimethyl PABA(Escalol 507) inhibits cell growth and DNA synthesis at low concentrations, and halted the cell cycle of MM96L cells (human melanoma cell line) at the G1 phase. Despite limited clinical data in humans, many studies have confirmed increased mutagenicity of Ethylhexyl Dimethyl PABA(Escalol 507) following exposure to sunlight, which suggests that this molecule is likely to contribute to onset of sun-induced cancer despite protecting the skin through absorption of UVB. For risk assessment, the no observed adverse effect level (NOAEL) chosen was 100 mg/kg bw/day in a 4 weeks oral toxicity study. Systemic exposure dosage (SED) was 0.588 mg/kg bw/day for maximum use of Ethylhexyl Dimethyl PABA(Escalol 507) in cosmetics. Based on the risk assessment and exposure scenarios conducted in this study, the margin of safety (MOS) was calculated to be 180.18 for a sunscreen containing 8% Ethylhexyl Dimethyl PABA(Escalol 507), which is the maximum level allowed by the relevant domestic authorities. Keywords: Ethylhexyl Dimethyl PABA(Escalol 507), Cosmetics, Sunscreen, Risk assessment, Toxicity Go to: INTRODUCTION Ethylhexyl Dimethyl PABA(Escalol 507) (CAS No. 21245-02-3) is an organic derivative of water-soluble PABA (4-aminobenzoic acid) included in sunscreen and other cosmetics. It is a yellow water-insoluble oily liquid with an ester bond formed by condensation of 2-ethylhexanol and dimethylaminobenzoic acid (Fig. 1). Ethylhexyl Dimethyl PABA(Escalol 507) is also known as padimate O, OD-PABA, or octyl dimethyl p-aminobenzoate (Table 1). The Ministry of Food and Drug Safety (MFDS) and US Food and Drug Administration (FDA) mandate that its concentration in any cosmetic product shall not exceed 8% (1). Previous animal studies showed that high concentrations of Ethylhexyl Dimethyl PABA(Escalol 507) may be toxic to the epididymis and caution should be exercised when administering this substance to infants younger than six months of age due lack of understanding of its metabolism and absorption (2). Previous risk assessment data for Ethylhexyl Dimethyl PABA(Escalol 507) includes potential toxicity data and national and international regulations only. The present study summarizes a risk assessment that included determination of the margin of safety (MOS) at concentrations in cosmetics allowed by domestic authorities, a summary of existing experimental toxicity data, and exposure data associated with the amount of use in domestic cosmetic products. An external file that holds a picture, illustration, etc. Object name is tr-35-131f1.jpg Fig. 1 Chemical structure of Ethylhexyl Dimethyl PABA(Escalol 507). Table 1 Ethylhexyl Dimethyl PABA(Escalol 507) nomenclature and classification CAS No. 21245-02-3 EINECS No. 244-289-3 INCI name Ethylhexyl Dimethyl PABA(Escalol 507) IUPAC name 2-Ethylhexyl 4-(dimethylamino)benzoate Synonyms Padimate O Octyl dimethyl p-aminobenzoate, Octyl dimethyl PABA 2-Ethylhexyl p-(dimethylamino)benzoate OD-PABA Adopted from Hazardous Substances Data Bank (HSDB) & ChemIDplus (2). Go to: PHYSICAL AND CHEMICAL PROPERTIES The range of purities of Ethylhexyl Dimethyl PABA(Escalol 507) used as a raw material for cosmetics is approximately 98–99.5%. It is an oily yellow liquid state with oil characteristics. It has a molecular weight of 277.4053. It is soluble in alcohol, and strong acid and base, but is insoluble in water and acetic acid (Table 2). Table 2 Chemico-physical properties of Ethylhexyl Dimethyl PABA(Escalol 507) Physical property Yellow liquid with oil characteristics Molecular weight 277.4053 pKa 6.027 Boiling point 387.8°C at 760 mmHg Melting point 242.5–243.5°C Ignition point 124.1°C Steam pressure 7.7 × 107 mmHg at 25°C Specific gravity 0.99 Solubility Dissolved in alcohol, HCl, KOH Not dissolved in acetic acid Dissolved in water at 25°C if 5.3 × 103 mg/L Density 1.0 ± 0.1 g/cm3 Adopted from HSDB (2). Go to: COSMETIC USE Ethylhexyl Dimethyl PABA(Escalol 507) is used in sunscreen and in a variety of beauty products. According to the Environmental Working Group (EWG) database, it is used in many products including lipstick, conditioner, shampoo, anti-aging agents, hair spray, and sunscreen. Use of Ethylhexyl Dimethyl PABA(Escalol 507) in non-cosmetic products has not been reported in Korea. According to a survey conducted by the MFDS the average concentration of Ethylhexyl Dimethyl PABA(Escalol 507) in cosmetic products is 1.25% (ranging from 0.5–2.0%). Go to: HAZARD IDENTIFICATION Single and repeated dose toxicity studies of Ethylhexyl Dimethyl PABA(Escalol 507) have identified various toxicities including skin irritation, reproductive toxicity, genotoxicity, and phototoxicity. Repeated dosing of experimental animals resulted in organ toxicity and organ pigmentation. The major proposed mechanism of Ethylhexyl Dimethyl PABA(Escalol 507) toxicity is DNA damage by light-modified Ethylhexyl Dimethyl PABA(Escalol 507). General toxicity In an acute toxicity study of Ethylhexyl Dimethyl PABA(Escalol 507), the LD50 in rats was 14,900 mg/kg (3) and no irritation was observed in a human patch test using white Vaseline® mixed with 8% Ethylhexyl Dimethyl PABA(Escalol 507). According to a report by the Scientific Committee on Cosmetology (SCC) (1999) (4), a 4-week oral administration study was conducted in rats in accordance with GLP principles. Ethylhexyl Dimethyl PABA(Escalol 507) was administered orally (by gavage) at doses of 0, 100, 300, and 1,000 mg/kg/day (Groups 1, 2, 3, and 4, respectively) to 10 male and female rats per group. An additional 5 male and 5 female rats were added to Groups 1 and 4 to evaluate the convalescence stage. No clinical symptoms were observed except salivation in Group 4 and decreased weight in Group 4 three to four weeks after administration, which did not normalize following the convalescence period. Gross inspections during autopsies of the animals found that the capsule of the spleen was severely degraded in one female in Group 4. A male in Group 4 (4/10) exhibited a softened testis and 8 males exhibited reduced testis size. No prostate, epididymis, or seminal vesicle abnormalities were observed. Three out of the five males in the Group 4 convalescence group exhibited reduced testis size. A female rat in Group 4 showed increased spleen weight, and the females in Groups 3 and 4 exhibited increased liver weight. Furthermore, the males in Group 4 exhibited liver weight gain and pituitary gland weight loss. Among the animals in the convalescence group, the males in Group 4 exhibited kidney weight gain, but showed no changes in testis or pituitary gland weights. Histopathological examinations showed moderate or moderately severe testicular atrophy in all males in Group 4 and epididymal edema in seven out of the ten males in Group 4. All males in Group 4 had spleen pigmentation, but spleen pigmentation was more conspicuous in the females in Group 3 and was extensive in the females in Group 4. The NOAEL was determined at 100 mg/kg/day based on pigmentation of the spleen (5). The SCC determined that this NOAEL may have been too conservative, so a NOAEL value of 300 mg/kg/day was assigned to Ethylhexyl Dimethyl PABA(Escalol 507) (4). No toxicity was observed in 20 rabbits administered 140 or 280 mg/kg/day of Ethylhexyl Dimethyl PABA(Escalol 507) for 13 weeks (4). Reproductive and developmental toxicity When 2 mL/kg daily Ethylhexyl Dimethyl PABA(Escalol 507) was applied to the skin of rats at 6 to 16 days of pregnancy, wavy ribs were observed on both sides of 7/56 fetuses and on one side of 2/56 fetuses. However, these observations were not attributed to Ethylhexyl Dimethyl PABA(Escalol 507) toxicity, as the rat species used in this study commonly exhibit wavy ribs (4). According to a report by Erol et al. (6), dermal exposure to OD-PABA did not affect pubertal development or thyroid function in female or male rats. As such, OD-PABA was not classified as an endocrine disrupting chemical. Mutagenicity/Genotoxicity In vivo micronucleus testing was conducted on mice to evaluate mutagenesis. Ethylhexyl Dimethyl PABA(Escalol 507) (5,000 mg/kg) was intraperitoneally injected into three groups of mice (n = 10 mice per group; 30, 48, or 72 hr), resulting in no mutagenesis (3). A chromosomal aberration test was performed in human lymphocytes. This assay is based on metabolic activation in response to the S9 mix. Ethylhexyl Dimethyl PABA(Escalol 507) was dissolved in ethanol at concentrations of 315 to 5,010 μg/mL. No chromosomal aberrations were observed (4). Carcinogenicity Ethylhexyl Dimethyl PABA(Escalol 507) is not considered carcinogenic per International Agency for Research on Cancer (IARC), Association Advancing Occupational and Environmental Health (ACGIH), US National Toxicology Program (NTP), and Occupational Safety and Health Administration (OSHA) (7). Ocular irritation Two percent Ethylhexyl Dimethyl PABA(Escalol 507) mixed with mineral oil was applied to the eyes of rabbits. No irritation was reported when both eyes are washed and left unattended (3). A slight irritation was observed in rabbit mucous membranes during a Draize test with 2% and 5% Ethylhexyl Dimethyl PABA(Escalol 507) in mineral oil (4). Skin irritation Five percent Ethylhexyl Dimethyl PABA(Escalol 507) mixed with mineral oil applied to rabbit skin did not cause irritation (3,8). In addition, a patch containing Ethylhexyl Dimethyl PABA(Escalol 507) dissolved in 4% white Vaseline® affixed to adult volunteers did not cause skin sensitization (3). No irritation was observed following application of 5% Ethylhexyl Dimethyl PABA(Escalol 507) to normal and damaged rabbit skin for 24 hr (4). A human patch test study showed no incidence of irritation following application of yellow soft paraffin with 5% Ethylhexyl Dimethyl PABA(Escalol 507) for 48 hr (4). When 1 mg/mL of estradiol was prescribed during the autumn and winter seasons to postmenopausal women (4 persons), women receiving hormone replacement therapy, women with sensitivity to Ethylhexyl Dimethyl PABA(Escalol 507), women with epilepsy, or women prescribed medications to control liver metabolism (aged between 54 and 63, body weight between 67 and 93 kg) along with Ethylhexyl Dimethyl PABA(Escalol 507) applied to their arm over a 10 cm2 area, daily for nine days, no skin irritation was observed (9). Skin sensitization Five percent Ethylhexyl Dimethyl PABA(Escalol 507) in mineral oil did not cause skin sensitization in guinea pigs. In addition, 50 μL of 0.1% Ethylhexyl Dimethyl PABA(Escalol 507) in saline was injected into ten guinea pigs, followed by nine additional 0.1 mL injections administered across three weeks. The guinea pigs did not exhibit sensitization when challenged with a 0.05 mL dose after a 12-week resting phase (4). No skin sensitization was observed in humans following application of 1.5% or 4% Ethylhexyl Dimethyl PABA(Escalol 507) mixed with white Vaseline® (3). Furthermore, 15 volunteers were instructed to apply soft paraffin containing 4% Ethylhexyl Dimethyl PABA(Escalol 507) for three weeks, followed by a challenge application after a two week rest phase, after which no skin sensitization was observed. Consistent with this result, 150 individuals subjected to a patch test with 7% Ethylhexyl Dimethyl PABA(Escalol 507) with 3% oxybenzone did not exhibit skin sensitization (4). Another study showed that application of soft paraffin containing 7% Ethylhexyl Dimethyl PABA(Escalol 507) to 156 individuals did not cause sensitization (4). Finally, a slight stinging reaction was reported during the induction period when a mixture of 3% benzophenone and 8% Ethylhexyl Dimethyl PABA(Escalol 507) was applied to 90 individuals, but no skin sensitization was observed (4). Phototoxicity/Photosensitization Ten guinea pigs had their ear hair removed and a mixture of 3% oxybenzone and 7% Ethylhexyl Dimethyl PABA(Escalol 507) was applied to one ear several times, and 8-methoxypsoralen was applied to the ears of two guinea pigs as a positive control. The guinea pigs were then exposed to UV radiation for two hours. No phototoxicity was observed. Furthermore, no phototoxicity was observed when Ethylhexyl Dimethyl PABA(Escalol 507) was applied to the posterior of guinea pigs for 2 hr followed by irradiation of 3 J/cm2 at 320–400 nm (4). No phototoxicity was observed in 26 individuals who were tested with 3% oxybenzone and 7% Ethylhexyl Dimethyl PABA(Escalol 507) (4). Furthermore, no phototoxicity was observed when 5% Ethylhexyl Dimethyl PABA(Escalol 507) in ethanol was applied and the site was irradiated with 30 J (4). Patch testing with a mixture of 2% oxybenzone and 7% Ethylhexyl Dimethyl PABA(Escalol 507) for 24 hr was conducted on ten white-skin individuals. Following removal of the patch, the site was irradiated with UVA for 12 min followed by 1 MED (minimal erythema dose) of UVB. No phototoxicity was observed in this study (4). Furthermore, human subjects treated every 26 hr with an emulsion of stearic acid (3%), water (91%), and 4% Ethylhexyl Dimethyl PABA(Escalol 507) showed no phototoxicity. Ethylhexyl Dimethyl PABA(Escalol 507) is harmless unless it is exposed to light. However, once activated by light, it directly damages DNA. Ethylhexyl Dimethyl PABA(Escalol 507) in commercially available sunscreen products can be activated by UVA, and to a greater extent by UVB, when exposed to sunlight (10). Toxicokinetics To determine whether a new metered-dose topical aerosol (MDTA) medication containing Ethylhexyl Dimethyl PABA(Escalol 507) as a skin penetration enhancer could enhance transdermal delivery of estradiol, estradiol MDTA containing Ethylhexyl Dimethyl PABA(Escalol 507) was applied to the abdomens of postmenopausal women for nine days and the levels of estradiol and estrone in the blood were measured daily via radioimmunoassay. Following MDTA treatment, 1 mg of estradiol sprayed onto three adjacent areas of skin (10 cm2) on the abdomens of each subject did not induce skin irritation. Blood estradiol concentrations were measured in four women (aged between 54 and 63 years, body weight between 67 and 93 kg). The average blood estradiol concentration was 53 pg/mL across the 9-day study period, which was significantly greater than the reference value of 13 pg/mL. (p < 0.001). This test confirmed that the MDTA containing Ethylhexyl Dimethyl PABA(Escalol 507) enhanced transdermal delivery of estradiol (9). 14C-labelled Ethylhexyl Dimethyl PABA(Escalol 507) in ethanol was applied to 100 cm2 of the forearms of each of four male and female subjects. The forearms were then covered with gauze for 24 hr after the ethanol completely evaporated. Blood was collected after 0, 2, 4, 8, 24, and 72 hr and urine was collected for 24 hr. No radioactivity was found in the blood samples while 2.45% and 1.18% radioactivity were found in the urine samples of the male and female subjects, respectively (average % of total radioactivity). The average radioactivity recovered after washing the skin at the application site was 95.7%. Assuming that 0.5 mg/cm2 was applied at a concentration of 8% to 1.8 m2, the total amount absorbed was 13 mg, or 0.2 mg/kg (4). An oil-in-water emulsion lotion was used for an in vitro percutaneous penetration test, and guinea pig and human skin were used as the membranes. HEPES-buffered Hank’s balanced salt solution containing gentamycin sulfate and bovine serum albumin was used as the aqueous solution in the receiving chamber. The total absorption rate of Ethylhexyl Dimethyl PABA(Escalol 507) transferred to the receiving chamber and the skin was 12.7 ± 2.5%. Evaluation of Ethylhexyl Dimethyl PABA(Escalol 507) metabolism was also included in this test. Guinea pig skin hydrolyzed approximately 13–35% of Ethylhexyl Dimethyl PABA(Escalol 507) transferred to the aqueous solution through esterase activity, while human skin hydrolyzed 37% of Ethylhexyl Dimethyl PABA(Escalol 507) (11). The value used for skin absorption in humans for the risk assessment was 2.45% based on the limited skin absorption data. Miscellaneous materials (including clinical data) Cell tests confirmed that Ethylhexyl Dimethyl PABA(Escalol 507) inhibited cell growth and DNA synthesis, and delayed cycle progression at 25–100 mg/mL. The CI80-13S cell line, a model of mitochondrial dysfunction, showed greater cell growth inhibition in response to ethylhexyl p-methoxycinnamate (EHMC) and PABA than the other cell lines. The pretreatment of MM96L with ethidium bromide (EtBr), which serve as mitochondrial inhibitors, followed by sunscreen treatment, resulted in apoptosis with increased uptake of ethidium bromide (12). When keratinocytes exposed to 5 MED of sunlight were treated with sunscreen containing Ethylhexyl Dimethyl PABA(Escalol 507) (SPF 15), the number of DNA strand breaks observed here was at least 75 times higher than that in cells treated with sunscreen that did not contain Ethylhexyl Dimethyl PABA(Escalol 507) (13). MCF-7, a human breast cancer cell line, was used to measure the estrogenic activity of Ethylhexyl Dimethyl PABA(Escalol 507). Cell proliferation rates were evaluated by attaching the estrogen receptor of Ethylhexyl Dimethyl PABA(Escalol 507), and 17β-estradiol was used as a positive control. The EC50 values for cell proliferation were 1.2 pM and 2.63 pM for 17β-estradiol and Ethylhexyl Dimethyl PABA(Escalol 507), respectively (14). Go to: DOSE-RESPONSE ASSESSMENT After toxicological data were reviewed to determine the optimal toxicity reference value, the NOAEL of Ethylhexyl Dimethyl PABA(Escalol 507) was selected from a 4-week repeated dose toxicity study in rats. Ethylhexyl Dimethyl PABA(Escalol 507) dissolved in corn oil was administered to rats at concentrations of 0, 100, 300, and 1,000 mg/kg/day for four weeks by gavage, followed by four weeks of convalescence to assess the durability or reversibility of toxic effects. The results following the first four weeks showed toxicities such as increased weight and histological changes in the testes, epididymis, spleen, and liver. The assessment of reversible toxicity following four weeks of convalescence confirmed the absence of toxicity except for semen reduction in the epididymis, which was only observed in the treatment group given 1,000 mg/kg/day of Ethylhexyl Dimethyl PABA(Escalol 507). Pigmentation of the spleen was observed among males subjected to high concentrations of Ethylhexyl Dimethyl PABA(Escalol 507). This observation was more conspicuous among females treated with 300 and 1,000 mg/kg/day of Ethylhexyl Dimethyl PABA(Escalol 507). Based on the pigmentation of the spleen, NOAEL was determined to be 100 mg/kg/day (5) (Table 3). The NOAEL was based on animal testing data and Ethylhexyl Dimethyl PABA(Escalol 507) was not considered to be of concern if the MOS was 100 or above. Based on the MOS determined using the use limit of Ethylhexyl Dimethyl PABA(Escalol 507) among domestic cosmetic products, the health risk of Ethylhexyl Dimethyl PABA(Escalol 507) for use of sunscreen was 180.18, which is significantly higher than 100, which confirmed the safety of Ethylhexyl Dimethyl PABA(Escalol 507). Go to: CONCLUSION Ethylhexyl Dimethyl PABA(Escalol 507) is an organic derivative of water-soluble PABA (4-aminobenzoic acid) used as an ingredient in sunscreen and other cosmetics. Ethylhexyl Dimethyl PABA(Escalol 507) induced pigmentation of the spleen in a four-week oral administration toxicity test in rats, and the NOAEL derived from this study was 100 mg/kg/day. No significant reproductive toxicity, genotoxicity, carcinogenicity, skin sensitization, skin irritation, or phototoxicity was observed in response to Ethylhexyl Dimethyl PABA(Escalol 507) administration. The optimal NOAEL for the risk assessment was determined to be 100 mg/kg/day based on a four-week repeated toxicity study in rats. The SED of Ethylhexyl Dimethyl PABA(Escalol 507) was 0.588. The risk characterization demonstrated that Ethylhexyl Dimethyl PABA(Escalol 507) is safe to use in cosmetics in accordance with current MFDS regulations because the MOS exceeded 100 even at the maximum permitted concentration in cosmetics (8%). However, the toxicological data used in the risk assessment are limited, and if new toxicological data are reported, further assessments should be performed as appropriate. Abstract Ethylhexyl Dimethyl PABA(Escalol 507)-aminobenzoic acid (PABA) is an oily yellow liquid derivative of water-soluble PABA commonly used in sunscreen. Ethylhexyl Dimethyl PABA(Escalol 507) is widely used as an ingredient in many cosmetics at an average concentration of 1.25% (0.5–2.0%) in Korea. Previous studies, including those involving animals, have demonstrated that Ethylhexyl Dimethyl PABA(Escalol 507) is toxic to the following four organs: testis, epididymis, spleen, and liver. In addition, experiments using human keratinocytes found that Ethylhexyl Dimethyl PABA(Escalol 507) inhibits cell growth and DNA synthesis at low concentrations, and halted the cell cycle of MM96L cells (human melanoma cell line) at the G1 phase. Despite limited clinical data in humans, many studies have confirmed increased mutagenicity of Ethylhexyl Dimethyl PABA(Escalol 507) following exposure to sunlight, which suggests that this molecule is likely to contribute to onset of sun-induced cancer despite protecting the skin through absorption of UVB. For risk assessment, the no observed adverse effect level (NOAEL) chosen was 100 mg/kg bw/day in a 4 weeks oral toxicity study. Systemic exposure dosage (SED) was 0.588 mg/kg bw/day for maximum use of Ethylhexyl Dimethyl PABA(Escalol 507) in cosmetics. Based on the risk assessment and exposure scenarios conducted in this study, the margin of safety (MOS) was calculated to be 180.18 for a sunscreen containing 8% Ethylhexyl Dimethyl PABA(Escalol 507), which is the maximum level allowed by the relevant domestic authorities.
ETHYLHEXYL DIMETHYL PABA ( OCTYL DIMETHYL PABA)
ETHYLHEXYL ETHYLHEXANOATE, N° CAS : 7425-14-1. Nom INCI : ETHYLHEXYL ETHYLHEXANOATE. Nom chimique : 2-Ethylhexyl 2-ethylhexanoate. N° EINECS/ELINCS : 231-057-1. Ses fonctions (INCI). Emollient : Adoucit et assouplit la peau
ETHYLHEXYL ETHYLHEXANOATE
ETHYLHEXYL HYDROXYSTEARATE. N° CAS : 29710-25-6 / 29383-26-4. Nom INCI : ETHYLHEXYL HYDROXYSTEARATE. Nom chimique : 2-Ethylhexyl 12-hydroxyoctadecanoate. N° EINECS/ELINCS : 249-793-7. Classification : Huile estérifiée. Ses fonctions (INCI). Emollient : Adoucit et assouplit la peau
ETHYLHEXYL HYDROXYSTEARATE
ETHYLHEXYL HYDROXYSTEARATE BENZOATE, N° CAS : 199277-69-5, Nom INCI : ETHYLHEXYL HYDROXYSTEARATE BENZOATE, Nom chimique : 2-Ethylhexyl 12-benzoyloxyoctadecanoate, Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau, Agent d'entretien de la peau : Maintient la peau en bon état
ETHYLHEXYL HYDROXYSTEARATE BENZOATE
ETHYLHEXYL ISOPALMITATE, N° CAS : 93843-32-4, Nom INCI : ETHYLHEXYL ISOPALMITATE. Nom chimique : 2-Ethylhexyl isohexadecanoate. N° EINECS/ELINCS : 299-112-2. Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau
ETHYLHEXYL ISOPALMITATE
ETHYLHEXYL ISOSTEARATE, N° CAS : 81897-25-8, Nom INCI : ETHYLHEXYL ISOSTEARATE. Nom chimique : Isooctadecanoic acid, 2-ethylhexyl ester. Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau
ETHYLHEXYL ISOSTEARATE
ETHYLHEXYL ISONONANOATE, N° CAS : 71566-49-9, Nom INCI : ETHYLHEXYL ISONONANOATE. Nom chimique : 2-Ethylhexyl isononanoate. N° EINECS/ELINCS : 275-637-2. Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau
Ethylhexyl isononanoate
ETHYLHEXYL LAURATE, N° CAS : 20292-08-4, Nom INCI : ETHYLHEXYL LAURATE. Nom chimique : 2-Ethylhexyl laurate. N° EINECS/ELINCS : 243-697-9. Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau
ETHYLHEXYL LAURATE
ETHYLHEXYL METHACRYLATE, N° CAS : 688-84-6, Nom INCI : ETHYLHEXYL METHACRYLATE. Nom chimique : 2-Ethylhexyl Methacrylate. Ses fonctions (INCI) :Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles
ETHYLHEXYL METHACRYLATE
SYNONYMS 2-ethylhexyl 4-methoxycinnamate;2-Ethylhexyl p-methoxycinnamate;2-Ethylhexyl-4-methoxycinnamat;2-Propenoic acid, 3-(4-methoxyphenyl)-, 2-ethylhexyl ester;3-(4-Methoxyphenyl)-2-propenoic acid 2-ethylhexyl ester;4-Methoxycinnamate de 2-ethylhexyle CAS NO:5466-77-3
ETHYLHEXYL METHOXYCINNAMATE
ETHYLHEXYL METHOXYCINNAMATE, N° CAS : 5466-77-3, Nom INCI : ETHYLHEXYL METHOXYCINNAMATE. Nom chimique : 2-Ethylhexyl 4-methoxycinnamate. N° EINECS/ELINCS : 226-775-7. Ses fonctions (INCI) : Absorbant UV : Protège le produit cosmétique contre les effets de la lumière UV. Filtre UV : Permet de filtrer certains rayons UV afin de protéger la peau ou les cheveux des effets nocifs de ces rayons.
ETHYLHEXYL MYRISTATE
ETHYLHEXYL OLEATE, N° CAS : 26399-02-0. Nom INCI : ETHYLHEXYL OLEATE. N° EINECS/ELINCS : 247-655-0. Ses fonctions (INCI). Emollient : Adoucit et assouplit la peau
ETHYLHEXYL OLEATE
Ethylhexyl Oleate is designed for use in a wide variety of applications where the properties of a high quality ester made from oleic acid are required.
Ethylhexyl Oleate is intended for uses where excellent color, stability and odor characteristics and natural origin are desired.
Ethylhexyl Oleate is clear liquid at room temperatures with a melting point around -20 ºC.

CAS Number: 26399-02-0
EC Number: 247-655-0
Molecular Formula: C26H50O2
Molecular Weight: 394.679

Ethylhexyl Oleate finds application in personal care formulations as an emollient or in lubricants as a friction modifier in engine oils or as a feed for further modification.
Ethylhexyl Oleate has been used as a viscocity control agent in personal care for products with high fat or wax contents, and for some other uses in lubricants and cosmetics such as bath oils, hair preparations and creams.

Ethylhexyl Oleate is Ethylhexyl Oleate made from our oleic acid and designed for use in a wide variety of applications where the properties of a high quality ester are required.
Ethylhexyl Oleate is intended for uses where excellent color, stability and odor characteristics and natural origin are desired.

Ethylhexyl Oleate finds application in personal care formulations as an emollient or in lubricants as a friction modifier in engine oils or as a feed for further modification.
Ethylhexyl Oleate has been used as a viscocity control agent in personal care for products with high fat or wax contents, and for some other uses in lubricants and cosmetics such as bath oils, hair preparations and creams.

Ethylhexyl Oleate is a branched mono-saturated fatty acid ester obtained from 2-ethylhexanol and oleic fatty acid, mainly from palm oil.
Clear liquid at room temperatures with a melting point around -20 ºC.

Ethylhexyl Oleate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Ethylhexyl Oleate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Global Ethylhexyl Oleate Market: Introduction
Nowadays, the usage of synthetic esters as an intermediate has become a trend in many industries owing to Ethylhexyl Oleate superior properties.
Ethylhexyl Oleate is a monoester, is easy to emulsify, and has better lubricity & hydraulic stability as compared to other esters.

Ethylhexyl Oleate is produced from vegetable oils as well as from synthetic base oils.
The production of Ethylhexyl Oleate from vegetable oils is a high technology invention in term of environment-friendly products as compared to the production from mineral oils.

Alternative names of Ethylhexyl Oleate are – 9-octadecenoic acid (9Z), 9-Octadecenoic acid (Z), 2-Ethylhexyl ester, etc.
In terms of physical appearance, Ethylhexyl Oleate is clear liquid, white-colored compound, and having molecular formulae C26H50O2.
Ethylhexyl Oleate is a biodegradable compound, non-flammable liquid and miscible with hydrocarbons, ethers, and acetones.

In term of applications, Ethylhexyl Oleate act as an oxidizing agent, binding agent, intermediate, and antiwear additive for lubricants and metalworking fluids.
Ethylhexyl Oleate finds a wide range of applications across various end-use industries including automotive, adhesive & sealants, chemicals, and other manufacturing industries

Global Ethylhexyl Oleate Market Dynamics
The global Ethylhexyl Oleate market is prominently driven by the increasing industrial infrastructure across the world.
Advancement in end-use industries, expansion of production facilities and marketing strategies of companies is anticipated to generate the demand for intermediates/raw materials such as Ethylhexyl Oleate.

The increase in demand for biodegradable products is expected to propel the global Ethylhexyl Oleate market throughout the forecast period.

Further, end-users are emphasizing on improvement of processing efficiencies, demanding better technical performance in operations, and enhance environmental safety.
Attributing to these factors, the demand for synthetic esters i.e. Ethylhexyl Oleate is projected to upsurge.
Conversely, the availability of substitutes such as 2-Ethylhexyl Tallowate, methyl esters, etc. is expected to restrain the global Ethylhexyl Oleate market over the forecast period.

Aligned with the global trend of sustainability, Ethylhexyl Oleate is making way, among other biodegradable products, emerging as a key trend for global Ethylhexyl Oleate market.

Global 2-Etylhexyl Oleate Market: Regional Outlook
The production of Ethylhexyl Oleate varies from region to region, which depends on the local feedstock availability.
In term of Ethylhexyl Oleate consumption, South East Asia Pacific is expected to be prominent region, and is projected to grow with a healthy CAGR in near future.

In addition, North America and Europe are also secured their position in the global Ethylhexyl Oleate market from past few years.
Expansion of end-use industries in the U.S., Canada, Germany, UK, Australia, etc. is influencing factor for the growth of North America and Europe Ethylhexyl Oleate market.

Furthermore, the Middle East & Africa and Oceania regions estimated to hold less than one-fourth market share in the global Ethylhexyl Oleate market and is projected to grow with a moderate growth rate during the forecast period.

Uses of Ethylhexyl Oleate:
Emollient:
Softener and conditioner

Industry Uses of Ethylhexyl Oleate:
Ethylhexyl Oleate is used in the following products: washing & cleaning products, metal surface treatment products, textile treatment products and dyes, polymers, pH regulators and water treatment products and lubricants and greases.
Ethylhexyl Oleate is used in the following areas: formulation of mixtures and/or re-packaging.

Ethylhexyl Oleate is used for the manufacture of: chemicals and textile, leather or fur.
Release to the environment of Ethylhexyl Oleate can occur from industrial use: in processing aids at industrial sites and in the production of articles.

Other Industry Uses:
Adhesives and sealant chemicals
Functional fluids (open systems)
Lubricants and lubricant additives
Processing aids, specific to petroleum production
Solvents (for cleaning and degreasing)
Lubricating agent
Surface active agents
Washing and cleaning products
Lubricants and greases
Polishes and waxes
Textile treatment products
Dyes and polymers.

Consumer Uses of Ethylhexyl Oleate:
Ethylhexyl Oleate is used in the following products: washing & cleaning products, lubricants and greases, adhesives and sealants, polishes and waxes, textile treatment products and dyes and polymers.
Release to the environment of Ethylhexyl Oleate can occur from industrial use: in the production of articles.
Other release to the environment of Ethylhexyl Oleate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).

Other Consumer Uses:
Adhesives and sealants
Cleaning and furnishing care products
Lubricants and greases
Paints and coatings
Lubricants and lubricant additives
Lubricating agent
Surface active agents

Widespread uses by professional workers of Ethylhexyl Oleate:
Ethylhexyl Oleate is used in the following products: washing & cleaning products and polishes and waxes.
Ethylhexyl Oleate is used in the following areas: formulation of mixtures and/or re-packaging.

Ethylhexyl Oleate is used for the manufacture of: chemicals.
Other release to the environment of Ethylhexyl Oleate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).

Ethylhexyl Oleate is classified as:
Cosmetics - Emollient

Cosmetic formulations of Ethylhexyl Oleate:
Skin conditioning, emollient

General Manufacturing Information of Ethylhexyl Oleate:

Industry Processing Sectors:
Fabricated Metal Product Manufacturing
Petroleum Lubricating Oil and Grease Manufacturing
Printing Ink Manufacturing
Printing and Related Support Activities
Wholesale and Retail Trade

Identifiers of Ethylhexyl Oleate:
CAS Number: 26399-02-0
Chem/IUPAC Name: Ethylhexyl Oleate
EINECS/ELINCS No: 247-655-0
COSING REF No: 33889

Display Name: Ethylhexyl Oleate
EC Number: 247-655-0
EC Name: Ethylhexyl Oleate
CAS Number: 26399-02-0
Molecular formula: C26H50O2
IUPAC Name: 2-ethylhexyl octadec-9-enoate

Molecular Formula: C26H50O2
Average mass: 394.674 Da
Monoisotopic mass: 394.381073 Da
ChemSpider ID: 4942537

Catalog Number: ACM26399020
Product Name: Ethylhexyl Oleate
CAS: 26399-02-0
Category: Heterocyclic Organic Compound
Molecular Formula: C26H50O2
Molecular Weight: 394.679
Density: 0.867 g/cm³

Properties of Ethylhexyl Oleate:
Molecular Weight: 394.7
XLogP3-AA: 10.7
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 22
Exact Mass: 394.381080833
Monoisotopic Mass: 394.381080833
Topological Polar Surface Area: 26.3 Ų
Heavy Atom Count: 28
Complexity: 348
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 1
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Ethylhexyl Oleate:
Acid Value: 1.0 Max
Saponification Value: 135 - 145
Hydroxyl Value: 1.0 Max
Color: 5 Gard Max
Moisture: 0.3% Max
Solubility: Insoluble
Insolubility: in water
Molecular weight: 394.69

Synonyms of Ethylhexyl Oleate:
Ethylhexyl Oleate
26399-02-0
ethylhexyl oleate
9-Octadecenoic acid (9Z)-, 2-ethylhexyl ester
2-Ethylhexanol oleic acid ester
2-ETHYLHEXYL (9Z)-OCTADEC-9-ENOATE
9-Octadecenoic acid (Z)-, 2-ethylhexyl ester
R34927QY59
UNII-R34927QY59
2-ethylhexyloleate
2-ethylhexyl (Z)-octadec-9-enoate
EINECS 247-655-0
SABODERM EO
SYMPATENS-EO
DUB OO
EC 247-655-0
AEC ETHYLHEXYL OLEATE
Oleic acid 2-ethylhexyl ester
SCHEMBL333602
Oleic acid, 2-ethylhexyl ester
ETHYLHEXYL OLEATE [INCI]
DTXSID90893468
(+/-)-ETHYLHEXYL OLEATE
BBA39902
2-ETHYLHEXYL 2-OCTADECENOATE
ETHYLHEXYL OLEATE, (+/-)-
AS-66491
2-OCTADECENOIC ACID, 2-ETHYLHEXYL ESTER
Q27287724
(9Z)-9-Octadécénoate de 2-éthylhexyle [French] [ACD/IUPAC Name]
247-655-0 [EINECS]
26399-02-0 [RN]
2-Ethylhexyl (9Z)-9-octadecenoate [ACD/IUPAC Name]
2-Ethylhexyl (9Z)-octadec-9-enoate
Ethylhexyl Oleate
2-Ethylhexyl-(9Z)-9-octadecenoat [German] [ACD/IUPAC Name]
9-Octadecenoic acid, 2-ethylhexyl ester, (9Z)- [ACD/Index Name]
ETHYLHEXYL OLEATE
2-Ethylhexyl 9-octadecenoate [ACD/IUPAC Name]
2-ethylhexyloleate
9-Octadecenoic acid [ACD/IUPAC Name]
9-Octadecenoic acid (9Z)-, 2-ethylhexyl ester
9-Octadecenoic acid (Z)-, 2-ethylhexyl ester
MFCD00072286
OLEIC ACID, 2-ETHYLHEXYL ESTER
ETHYLHEXYL PALMITATE
Ethylhexyl palmitate is a mixture of a fatty alcohol and palmitic acid that functions in cosmetics products as an emollient (meaning it can soften and smooth skin), texture enhancer, and solvent in amounts from 2-50%, depending on the type of formula and desired aesthetics.
Ethylhexyl palmitate improves the look of skin, particularly dry skin, by helping reduce moisture loss from its upper layers.
As a solvent, Ethylhexyl palmitate helps solubilize other ingredients, helping active ingredients more readily penetrate skin.

CAS: 16958-85-3
MF: C24H48O2
MW: 368.64
EINECS: 241-028-5

Ethylhexyl palmitate helps sunscreen active ingredients such as avobenzone and ethylhexyl triazone disperse and remain evenly suspended in a formula.
Ethylhexyl palmitate has a feel like some silicones and silicone derivatives, making it an alternative to those ingredients in certain formulations.
There’s no research indicating this ingredient, which may be synthetic, plant-, or animal-derived, is a problem for skin.
Ethylhexyl palmitate, or octyl palmitate, is the fatty acid ester derived from 2-ethylhexanol and palmitic acid.
Ethylhexyl palmitate is commonly used in cosmetic formulations.

Ethylhexyl palmitate is a derivative of palm oil often used as an organic replacement to silicone.
Ethylhexyl palmitate has a 'dry-slip' feel that is very similar to silicone's texture.
Ethylhexyl palmitate is found in many skin care products as an ingredient used to adjust the consistency.
Ethylhexyl Palmitate, also called Octyl Palmitate, is a clear, colorless, practically odorless liquid.
Ethylhexyl palmitate is a white, crystalline, wax-like substance.
Ethylhexyl palmitate is a colorless, almost odorless, liquid.

In cosmetics and personal care products, the Palmitates are used in a wide spectrum of products.
Ethylhexyl palmitate, also known as octyl palmitate, is an ester of 2-ethyl hexanol and palmitic acid.
Ethylhexyl palmitate is a fatty acid found naturally in plants and animals.
Ethylhexyl palmitate is a derivative of palm oil.
Ethylhexyl palmitate comes as a clear, colorless and odorless liquid, but according to source it also comes as an amber-colored liquid.

Ethylhexyl Palmitate (2-ethylhexyl palmitate) is an ester of 2-ethylhexanol and palmitic acid, a multifunctional skincare ingredient that improves the skin feel of the final product.
Ethylhexyl palmitate's the perfect replacement for mineral oils like petrolatum.
This multi-purpose ester provides a more decadent skin feel and imparts “mid-feel” to emulsion during rub-out.
Ethylhexyl Palmitate is a non-occlusive emollient with medium spreading properties.
In addition, Ethylhexyl palmitate may act as a carrying agent and solvent for other ingredients, fixative for fragrance, and pigment wetting agent in decorative cosmetics.

2-ETHYLHEXYL PALMITATE Chemical Properties
Boiling point: 414.2±13.0 °C(Predicted)
Density: 0.860±0.06 g/cm3(Predicted)
Solubility: Chloroform (Slightly), Hexanes (Slightly)
Form: Solid
Color: Off-White
LogP: 10.975 (est)
EPA Substance Registry System: Ethylhexyl palmitate (16958-85-3)

Ethylhexyl palmitate is a clear, colorless liquid at room temperature with a slightly fatty odor.
Ethylhexyl palmitate and 2-ethylhexanol are reacted in the presence of an acid catalyst to make the ester.
Ethylhexyl palmitate is a branched saturated fatty ester derived from ethylhexyl alcohol and palmitic acid.

Uses
Apart from being a natural option for solvent in any preparation, Ethylhexyl palmitate can also be used to replace silicone.
Ethylhexyl palmitate has a very light feel on the skin and is non-tacky also.
Ethylhexyl palmitate forms a thin film over the skin or hair, and it does not let skin lose its inherent moisture, which otherwise can be lost in the process of exposure to the harsh environment, such as wind, sunlight or pollutants.
Silicones have a “dry-slip” feel on the skin, meaning moisturized nongreasy skin, the Ethylhexyl palmitate also provides a similar effect.

That’s the reason Ethylhexyl palmitate is an ideal choice as a solvent as a carrying agent and fragrance fixative.
Pigments or colorants even dispersion is very much significant in case of any cosmetic preparation, Ethylhexyl palmitate should deliver uniform quality from the first to last use, at this point octyl palmitate is used to wet pigments and produce uniform dispersion.
Ethylhexyl palmitate is used in skincare products, sun pre/post care products, color cosmetics, and pressed powders.

Ethylhexyl palmitate is used in cosmetic formulations as a solvent, carrying agent, pigment wetting agent, fragrance fixative and emollient.
Ethylhexyl palmitate's dry-slip skinfeel is similar to some silicone derivatives.
Ethylhexyl palmitate is an ingredient that is used to improve the texture, feel, and the scent of skincare and cosmetic products.
Ethylhexyl palmitate functions as an emollient, solvent, and fragrance fixative.

Ethylhexyl palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid.
Ethylhexyl palmitate can be found in natural plant fragrances and also synthetically produced.
Ethylhexyl palmitate is the most common saturated fatty acid found in animals, plants and microorganisms, and is a major component of palm oil.
Ethylhexyl palmitate is a clear, colorless liquid at room temperature with a slightly fatty odor.
Ethylhexyl palmitate is insoluble in water but mildly dissolves in oils.
In cosmetics and skincare products, Ethylhexyl palmitate functions as an emollient, solvent, and fragrance fixative.

Moisture
As an emollient, Ethylhexyl palmitate helps to keep the skin moist and supple by reducing water loss from the top layers of the skin.
Emollients also act as lubricants by reducing friction when anything rubs against the skin.
Ethylhexyl palmitate is considered to be a non-occlusive emollient, which means it does not form a film on the surface of the skin.
Ethylhexyl palmitate is often used as an organic replacement to silicones in a cosmetic formulation because Ethylhexyl palmitate provides a dry-slip, silky feel that is very similar to how a silicone would feel.

While all skin types can benefit from emollients like Ethylhexyl palmitate, emollients are very beneficial for those who have dry, rough, and/or flaky skin.
Emollients can treat these symptoms, leaving the skin looking and feeling soft and smooth. In addition, emollients may be suitable for those that suffer from conditions such as eczema, psoriasis, or other inflammatory skin conditions.

Solvent
Ethylhexyl palmitate functions as a solvent by helping other ingredients dissolve.
Solvents can also increase the efficacy of active ingredients in a formulation by enhancing their absorption through the skin.

Appearance
Another function of ethylhexyl palmitate in cosmetics is as a pigment wetting agent.
Wetting agents work by reducing the interfacial tension between two different types of ingredients in a cosmetic formulation.
Wetting agents are useful in makeup as they improve the pigment or color distribution in the formulation.
Think about even eyeshadow or foundation pigment.

Fragrance
Lastly, ethylhexyl palmitate functions as a fragrance fixative in cosmetics and skincare products.
A fixative helps to equalize the volatile fragrance components making them last longer and remain more stable on the skin.

Synonyms
2-ETHYLHEXYL PALMITATE
29806-73-3
2-Ethylhexyl hexadecanoate
Elfacos EHP
Hexadecanoic acid, 2-ethylhexyl ester
Palmitic acid, 2-ethylhexyl ester
Ceraphyl 368
Wickenol 155
EINECS 249-862-1
AI3-31580
UNII-2865993309
EC 249-862-1
SCHEMBL15529
DTXSID3027958
Palmitic acid 2-ethylhexyl ester
Palmitic acid-2-ethylhexyl ester
(2-ETHYLHEXYL) PALMITATE
ETHYLHEXYL PALMITATE [INCI]
(+/-)-ETHYLHEXYL PALMITATE
ETHYLHEXYL PALMITATE [VANDF]
MFCD00072255
ETHYLHEXYL PALMITATE [WHO-DD]
AKOS016010384
ETHYLHEXYL PALMITATE, (+/-)-
AS-15135
CS-0063978
E1435
FT-0709066
D97727
EN300-1719134
A876381
J-017652
ETHYLHEXYL PALMITATE
Ethylhexyl Palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid.
Ethylhexyl palmitate, or octyl palmitate, is the fatty acid ester derived from 2-ethylhexanol and palmitic acid.
Ethylhexyl palmitate is a clear, colorless liquid at room temperature with a slightly fatty odor.


CAS Number: 29806-73-3
EC Number: 249-862-1
Chemical formula: C24H48O2
Chem/IUPAC Name: Octan-3-yl hexadecanoate, 2-Ethylhexyl Ester


Ethylhexyl Palmitate is a super common, medium-spreading emollient ester that gives richness to the formula and a mild feel during rubout.
Ethylhexyl Palmitate can be a replacement for mineral oil and is often combined with other emollients to achieve different sensorial properties.
Ethylhexyl palmitate has a feel like some silicones and silicone derivatives, making it an alternative to those ingredients in certain formulations.


There’s no research indicating Ethylhexyl Palmitate, which may be synthetic, plant-, or animal-derived, is a problem for skin.
Ethylhexyl palmitate is a fatty acid ester that is used as an emollient in cosmetic formulations.
Ethylhexyl Palmitate is a clear, colorless, liquid at room temperature bearing a faintly fatty smell.


Ethylhexyl Palmitate imparts a richness to a formula and can be a replacement for mineral oil.
Ethylhexyl palmitate is obtained from the reaction of palmitic acid, a very common fatty acid, with 2-ethyl hexanol, in the presence of an acid catalyst.
Ethylhexyl Palmitate is an ester of 2-ethylhexanol and palmitic acid. Ethylhexyl Palmitate's saponification value is 130 - 160.


Ethylhexyl Palmitate has medium spreading.
Ethylhexyl Palmitate can replace mineral oil in formulations.
Ethylhexyl palmitate, or octyl palmitate, is the fatty acid ester derived from 2-ethylhexanol and palmitic acid.


Ethylhexyl palmitate is a branched saturated fatty ester derived from ethylhexyl alcohol and palmitic acid.
Ethylhexyl palmitate is a clear, colorless liquid at room temperature with a slightly fatty odor.
Palmitic acid and 2-ethylhexanol are reacted in the presence of an acid catalyst to make the ester.


Ethylhexyl Palmitate is a clear colorless, practically odorless liquid.
Ethylhexyl Palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid.
Ethylhexyl Palmitate (2-ethylhexyl palmitate or Octyl palmitate) is an ester of 2-ethyl hexanol and palmitic acid, a multifunctional skincare ingredient that improves the skin feel of the final product.


Ethylhexyl Palmitate's an emollient ester and a perfect replacement for mineral oils like petrolatum.
Ethylhexyl Palmitate is a renewable palm derivative with a variety of uses in both personal care and industrial applications.
Ethylhexyl Palmitate is a clear low viscosity liquid with little odor.


Ethylhexyl palmitate provides slip and lubricity to skin preparations and is a good anti-tack agent in antiperspirants, creams, and lotions.
This multi-purpose ester provides a more decadent skin feel and imparts “mid-feel” to emulsion during rub-out.
Ethylhexyl palmitate has a feel like some silicones and silicone derivatives, making it an alternative to those ingredients in certain formulations.


There’s no research indicating this ingredient, which may be synthetic, plant-, or animal-derived, is a problem for skin.
Ethylhexyl Palmitate is oil soluble, and is supplied as a clear to off-white liquid.
Ethylhexyl palmitate, also known as octyl palmitate, is an ester of 2-ethyl hexanol and palmitic acid.


Palmitic acid is a fatty acid found naturally in plants and animals.
Ethylhexyl Palmitate is a derivative of palm oil.
Ethylhexyl Palmitate comes as a clear, colorless and odorless liquid, but according to source it also comes as an amber-colored liquid.


Ethylhexyl Palmitate is ester of 2-ethylhexanol and palmitic acid.
Ethylhexyl Palmitate can be added to formulas as is, add to oil phase, use level 2-50%.
Ethylhexyl Palmitate is a branched saturated fatty acid ester obtained from 2-ethylhexanol and palmitic fatty acid, from palm oil.


Ethylhexyl Palmitate is clear liquid at room temperatures with a melting point around -30 ºC.
Ethylhexyl Palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid.
Ethylhexyl Palmitate is an alternate to silicone-based ingredients offering a 'dry-slip' feel.


Ethylhexyl palmitate is a clear, colorless liquid at room temperature with a slightly fatty odor.
Ethylhexyl Palmitate is insoluble in water but mildly dissolves in oils.
Ethylhexyl Palmitate is a high quality colorless liquid with the added benefit of sustainable manufacturing.


Ethylhexyl Palmitate, also known as octyl palmitate, is a fatty acid ester that comes from 2-ethylhexanol and palmitic acid which is used in cosmetic formulations.
Ethylhexyl palmitate, or octyl palmitate, is the ester of 2-ethylhexyl alcohol (which occurs in essential oils) and palmitic acid (obtained from palm trees).



USES and APPLICATIONS of ETHYLHEXYL PALMITATE:
Ethylhexyl palmitate is used in cosmetic formulations as a solvent, carrying agent, pigment wetting agent, fragrance fixative and emollient.
Ethylhexyl Palmitate's dry-slip skinfeel is similar to some silicone derivatives.
As a solvent, Ethylhexyl Palmitate helps solubilize other ingredients, helping active ingredients more readily penetrate skin.


Ethylhexyl Palmitate is a mixture of a fatty alcohol and palmitic acid that functions in cosmetics products as an emollient (meaning it can soften and smooth skin), texture enhancer, and solvent in amounts from 2-50%, depending on the type of formula and desired aesthetics.
Ethylhexyl Palmitate improves the look of skin, particularly dry skin, by helping reduce moisture loss from its upper layers.


Ethylhexyl Palmitate helps sunscreen active ingredients such as avobenzone and ethylhexyl triazone disperse and remain evenly suspended in a formula.
Ethylhexyl Palmitate is non-occlusive emollient that provides a silky feel in various skin and hair care products.
Ethylhexyl palmitate is commonly used in cosmetic formulations.


Ethylhexyl Palmitate, also known as Octyl Palmitate, is a renewable palm derivative used primarily in cosmetic applications.
Ethylhexyl Palmitate has similar properties to Isopropyl Palmitate, and it can be used in place of Silicone in some applications.
Ethylhexyl Palmitate is used in cosmetic formulations as a solvent, carrying agent, wetting agent, emollient, and used mostly in the formulation of, eye/skin makeup, lipstick and skin care products.


Ethylhexyl Palmitate also widely used in metal working fluids, textile auxiliaries and lube & grease.
Ethylhexyl Palmitate, also known as octyl palmitate, is a fatty acid ester that comes from 2-ethylhexanol and palmitic acid which is used in cosmetic formulations.


Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.
Ethylhexyl Palmitate is a non-occlusive emollient with medium-spreading properties.


In addition, Ethylhexyl palmitate may be used as a carrying agent and solvent for other ingredients, a fixative for fragrance, and a pigment-wetting agent in decorative cosmetics.
Ethylhexyl Palmitate is used in skin, hair, and makeup products at a typical use level of 5-50 %.


Ethylhexil Palmitate (also known as Octyl Palmitate) is derived by esterification from Coconut oil and Palm oil and is frequently used as a vegetable-derived alternative to oil-based silicones.
Ethylhexyl Palmitate gives a dry touch to emulsions, increases their spreadability and improves their texture.


Ethylhexyl Palmitate is a fantastic non-occlusive emollient and skin conditioner, leaving the skin soft and smooth.
Ethylhexyl Palmitate is also used as a solvent, carrying agent and fragrance fixative.
As a pigment-wetting agent, Ethylhexyl Palmitate works well with zinc oxide and titanium dioxide in sun creams or in makeup preparations.


Ethylhexyl Palmitate is used Sun creams, body lotions, face creams, serums, makeup, makeup removers, homemade fragrances.
Ethylhexyl Palmitate is a specialty emollient ester.
Ethylhexyl Palmitate acts as a superior emollient, carrying agent, pigment wetting agent, and solvent derived from palm oil.


Ethylhexyl Palmitate is a great replacement for mineral oil.
Ethylhexyl Palmitate is suitable for use in lotions, creams, sunscreens, hair care, and lip care.
Ethylhexyl Palmitate is used for external use only.


Ethylhexyl Palmitate is used Color cosmetics, pressed powders, skin care product, sun care products.
Ethylhexyl Palmitate helps adjust consistency in skin-care products.
Ethylhexyl palmitate is a mixture of a fatty alcohol and palmitic acid that functions in cosmetics products as an emollient (meaning it can soften and smooth skin), texture enhancer, and solvent in amounts from 2–50%, depending on the type of formula and desired aesthetics.


Ethylhexyl Palmitate improves the look of skin, particularly dry skin, by helping reduce moisture loss from its upper layers.
As a solvent, Ethylhexyl Palmitate helps solubilize other ingredients, helping active ingredients more readily penetrate skin.
Ethylhexyl Palmitate helps sunscreen active ingredients such as avobenzone and ethylhexyl triazone disperse and remain evenly suspended in a formula.


Ethylhexyl palmitate has a feel like some silicones and silicone derivatives, making it an alternative to those ingredients in certain formulations.
There’s no research indicating Ethylhexyl Palmitate, which may be synthetic, plant-, or animal-derived, is a problem for skin.
Ethylhexyl palmitate is an ingredient that is used to improve the texture, feel, and the scent of skincare and cosmetic products.


Ethylhexyl Palmitate functions as an emollient, solvent, and fragrance fixative.
In cosmetics and skincare products, ethylhexyl palmitate functions as an emollient, solvent, and fragrance fixative.
Cosmetic formulations of Ethylhexyl Palmitate: emolient, fragrance ingredient, skin conditioning agent.


Industrial uses of Ethylhexyl Palmitate: washing and cleaning products manufacturer, polymers, adhesives and sealants, textile treatment products and dyes, lubricants and greases.
Ethylhexyl Palmitate is also an emollient used in skin care products.


Ethylhexyl Palmitate is capable of enhancing perfume retention in products.
Ethylhexyl Palmitate is widely used as a Re-Fatting agent.
Ethylhexyl Palmitate is considered a technology used in cosmetic ingredients.


Ethylhexyl Palmitate functions like Conditioners and Emollients, Emulsifiers, Solubilizers, and Dispersants.
Ethylhexyl Palmitate is beneficial for long-lasting fragrance release.
Ethylhexyl Palmitate is prominently used in personal care products, beauty care products, and skincare products.


Ethylhexyl Palmitate is recommended for the skin to apply in the form of body creams and lotions.
And in Personal care products, Ethylhexyl Palmitateis used in creams and lotions.
Ethylhexyl Palmitate is used excellent moisturiser with low comedogenicity.


Ethylhexyl Palmitate has branched chain, light non-greasy oil.
Ethylhexyl Palmitate is used in facial and body products including sunscreens.
Ethylhexyl Palmitate is used good mineral oil alternative.


Ethylhexyl Palmitate is used non-oily feel; low congealing point; low viscosity; hydrolysis and oxidation stability.
Ethylhexyl palmitate is used in cosmetic formulations as a solvent, carrying agent, pigment wetting agent, fragrance fixative and emollient.
Ethylhexyl Palmitate is a skin conditioning agent, an emollient and perfuming.


Ethylhexyl Palmitate can be used in a great range of products including lipstick, foundation, eye shadow, sunscreens, hand creams, deodorants, styling gel/lotions, beard care, fragrance for men, diaper cream, body art.
EHP with the chemical name Ethyl Hexyl Palmitate is a wetting agent used for powders in makeup formulations.


-Cosmetic Uses: perfuming agents
skin conditioning - emollient


-Skin care:
Ethylhexyl Palmitate softens and smoothens the skin.
Ethylhexyl Palmitate reduces moisture loss from the upper layers and improves the look of the skin.
As a solvent, Ethylhexyl Palmitate helps solubilize other ingredients, helping active ingredients more readily penetrate into the skin.
Ethylhexyl Palmitate helps active ingredients such as avobenzone and ethylhexyl triazone, commonly found in sunscreen, disperse and remain evenly suspended in a formula


-Hair care:
Ethylhexyl Palmitate works as a medium-spreading emollient and gives the hair a silky appearance
-Cosmetics
Ethylhexyl Palmitate works as a Solvent, Carrying Agent, Pigment Wetting Agent, Fragrance Fixative and Emollient in Cosmetics



USE AND BENEFITS OF ETHYLHEXYL PALMITATE:
Apart from being a natural option for solvent in any preparation, Ethylhexyl Palmitate can also be used to replace silicone.
Ethylhexyl Palmitate has a very light feel on the skin and is non-tacky also.

Ethylhexyl Palmitate forms a thin film over the skin or hair, and it does not let skin lose its inherent moisture, which otherwise can be lost in the process of exposure to the harsh environment, such as wind, sunlight or pollutants.
Silicones have a “dry-slip” feel on the skin, meaning moisturized nongreasy skin, the Ethylhexyl Palmitate also provides a similar effect.

That’s the reason Ethylhexyl Palmitate is an ideal choice as a solvent as a carrying agent and fragrance fixative.
Pigments or colorants even dispersion is very much significant in case of any cosmetic preparation, it should deliver uniform quality from the first to last use, at this point Ethylhexyl Palmitate is used to wet pigments and produce uniform dispersion.
Ethylhexyl Palmitate is used in skincare products, sun pre/post care products, color cosmetics, and pressed powders.



BENEFITS OF ETHYLHEXYL PALMITATE:
*Non-occlusive emollient that provides a silky feel in various skin and hair care products
*Medium spreading
*Can replace mineral oil in formulations



CHEMICAL PROPERTIES OF ETHYLHEXYL PALMITATE:
Ethylhexyl palmitate is a colorless, odorless liquid derived from palm oil that’s used as a skin conditioning emollient and to give products their slip.
Ethylhexyl Palmitate's similar in texture and sometimes used as an alternative to silicone.
Ethylhexyl palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid.
2-ethylhexyl alcohol can be found in natural plant fragrances and also synthetically produced.
Palmitic acid is the most common saturated fatty acid found in animals, plants and microorganisms, and is a major component of palm oil.



WHAT DOES ETHYLHEXYL PALMITATE DO IN A FORMULATION?
*Emollient
*Perfuming
*Solvent



FUNCTIONS OF ETHYLHEXYL PALMITATE:
*Emollient
*Carrier Solvent
*Fixative Pigment
*wetting agent



ETHYLHEXYL PALMITATE:
*A derivative of palm oil lipid and is an ultra mild, skin smoothing ester
*Used in cosmetic formulations as a solvent, carrying agent, pigment wetting agent, fragrance fixative and emollient
*Ethylhexyl palmitate is a derivative of palm oil often used as an organic replacement to silicone.
*Ethylhexyl Palmitate has a 'dry-slip' feel that is very similar to silicone's texture.
*Ethylhexyl Palmitate is found in many skin care products as an ingredient used to adjust the consistency.



FUNCTIONS OF ETHYLHEXYL PALMITATE:
*Emollient:
Ethylhexyl Palmitate softens and softens the skin
*Fragrant agent:
Ethylhexyl Palmitate is used for perfume and aromatic raw materials



ETHYLHEXYL PALMITATE AT A GLANCE:
*Helps soften and smooth skin
*Reduces moisture loss from skin’s upper layers
*Can help active ingredients more readily penetrate skin
*Is used as an alternative to silicone in some skin care products



WHAT IS ETHYLHEXYL PALMITATE USED FOR?
In addition to being used as an emollient in cosmetics, Ethylhexyl Palmitate is also used as a solvent, carrying agent, pigment-wetting agent, and fragrance fixative.



SAFETY PROFILE OF ETHYLHEXYL PALMITATE:
Ethylhexyl palmitate is not known to pose any health hazards to the skin or the body.
Ethylhexyl Palmitate is considered as safe for use in cosmetics.



ALTERNATIVES OF ETHYLHEXYL PALMITATE:
*COCOCAPRYLATE
*BUTYLENE GLYCOL DICAPRYLATE DICAPRATE



WHAT IS ETHYLHEXYL PALMITATE?
Ethylhexyl Palmitate, also called Octyl Palmitate, is a clear, colorless, practically odorless liquid.
Cetyl Palmitate is a white, crystalline, wax-like substance.
Isopropyl Palmitate is a colorless, almost odorless, liquid.
In cosmetics and personal care products, the Palmitates are used in a wide spectrum of products.



WHY IS ETHYLHEXYL PALMITATE USED IN COSMETICS AND PERSONAL CARE PRODUCTS?
The Palmitate ingredients act as lubricants on the skin’s surface, which gives the skin a soft and smooth appearance.
Isopropyl Palmitate may be used as a binder which is an ingredient added to compounded dry powder mixtures of solids to provide adhesive qualities during and after compression to make tablets or cakes.



SCIENTIFIC FACTS OF ETHYLHEXYL PALMITATE:
The Palmitates are produced using palmitic acid, a naturally occurring fatty acid found in plants and animals, along with smaller amounts of other fatty acids.
Cetyl Palmitate also occurs naturally as a chief constituent of spermaceti (wax from sperm whale oil) and can be found in staghorn coral.



MOISTURE OF ETHYLHEXYL PALMITATE:
As an emollient, Ethylhexyl Palmitate helps to keep the skin moist and supple by reducing water loss from the top layers of the skin.
Emollients also act as lubricants by reducing friction when anything rubs against the skin.
Ethylhexyl palmitate is considered to be a non-occlusive emollient, which means it does not form a film on the surface of the skin.

Ethylhexyl Palmitate is often used as an organic replacement to silicones in a cosmetic formulation because it provides a dry-slip, silky feel that is very similar to how a silicone would feel.
While all skin types can benefit from emollients like ethylhexyl palmitate, emollients are very beneficial for those who have dry, rough, and/or flaky skin.

Emollients can treat these symptoms, leaving the skin looking and feeling soft and smooth.
In addition, emollients may be suitable for those that suffer from conditions such as eczema, psoriasis, or other inflammatory skin conditions.



SOLVENT:
Ethylhexyl palmitate functions as a solvent by helping other ingredients dissolve.
Solvents can also increase the efficacy of active ingredients in a formulation by enhancing their absorption through the skin.



APPEARANCE OF ETHYLHEXYL PALMITATE:
Another function of ethylhexyl palmitate in cosmetics is as a pigment wetting agent.
Wetting agents work by reducing the interfacial tension between two different types of ingredients in a cosmetic formulation.
Wetting agents are useful in makeup as they improve the pigment or color distribution in the formulation.
Think about even eyeshadow or foundation pigment.



FRAGRANCE OF ETHYLHEXYL PALMITATE:
Lastly, Ethylhexyl Palmitate functions as a fragrance fixative in cosmetics and skincare products.
A fixative helps to equalize the volatile fragrance components making them last longer and remain more stable on the skin.



PHYSICAL and CHEMICAL PROPERTIES of ETHYLHEXYL PALMITATE:
Chemical formula: C24H48O2
Molar mass: 368.646 g·mol−1
Boiling Point: 398.93°C
Melting Point: 2°C
Solubility: Soluble in chloroform and hexanes
Appearance: colorless liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 399.00 to 402.00 °C. @ 760.00 mm Hg (est)
Flash Point: 399.00 °F. TCC ( 203.70 °C. ) (est)
logP (o/w): 10.819 (est)
Soluble in: alcohol, water, 4.127e-006 mg/L @ 25 °C (est)
Molecular Weight: 368.6 g/mol
XLogP3-AA: 10.6
Hydrogen Bond Donor Count: 0

Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 21
Exact Mass: 368.365430770 g/mol
Monoisotopic Mass: 368.365430770 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Count: 26
Formal Charge: 0
Complexity: 288
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Physical state: liquid
Colour: various
Odour: characteristic
pH (value): not determined
Melting point/freezing point: Initial boiling point and boiling range: not determined
Flash point: 210 °C at 1,013 hPa
Evaporation rate: not determined
Flammability (solid, gas): not relevant, (fluid)
Explosive limits: not determined
Vapour pressure: 0 Pa at 25 °C
Density: 0.859 g /cm³ at 20 °C
Vapour density this information is not available
Solubility(ies): Water solubility 0 mg/l at 25 °C
Partition coefficient: n-octanol/water (log KOW) 10.61
Soil: organic carbon/water (log KOC) 6.728
Auto-ignition temperature: not determined

Viscosity
Kinematic viscosity: 2.8 mm²/s at 100 °C
Explosive properties: none
Oxidising properties: none
Other information: Solvent content 100 %
Melting point: 2 °C
Boiling point: 398.93°C (rough estimate)
Density: 0.8789 (rough estimate)
refractive index: 1.4463 (estimate)
storage temp.: Refrigerator
solubility: Chloroform (Slightly), Hexanes (Slightly)
form: Solid
color: Off-White
Specific Gravity: 0.86
Water Solubility: 4.13ng/L at 25℃
LogP: 10.819 (est)



FIRST AID MEASURES of ETHYLHEXYL PALMITATE:
-Description of first aid measures:
*General notes:
Keep affected person warm, still and covered.
Take off immediately all contaminated clothing.
Never give anything by mouth.
*Following inhalation:
Provide fresh air.
*Following skin contact:
Wash with plenty of soap and water.
*Following eye contact:
Remove contact lenses, if present and easy to do.
Continue rinsing.
Irrigate copiously with clean, fresh water for at least 10 minutes, holding the eyelids apart.
*Following ingestion:
Rinse mouth with water (only if the person is conscious).
Do NOT induce vomiting.
-Indication of any immediate medical attention and special treatment needed:
none



ACCIDENTAL RELEASE MEASURES of ETHYLHEXYL PALMITATE:
-Personal precautions, protective equipment and emergency procedures:
*For non-emergency personnel:
Remove persons to safety.
-Environmental precautions:
Keep away from drains, surface and ground water.
Retain contaminated washing water and dispose of it.
-Methods and material for containment and cleaning up:
*Advice on how to contain a spill:
Covering of drains
*Advice on how to clean up a spill:
Wipe up with absorbent material (e.g. cloth, fleece).
*Collect spillage:
sawdust, kieselgur (diatomite), sand, universal binder
-Appropriate containment techniques:
Use of adsorbent materials.
-Other information relating to spills and releases:
Place in appropriate containers for disposal.
Ventilate affected area.



FIRE FIGHTING MEASURES of ETHYLHEXYL PALMITATE:
-Extinguishing media:
*Suitable extinguishing media:
Water spray
BC-powder
Carbon dioxide (CO2)



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLHEXYL PALMITATE:
-Exposure controls:
--Appropriate engineering controls:
General ventilation.
-Individual protection measures (personal protective equipment):
*Eye/face protection:
Wear eye/face protection.
*Hand protection:
Wear suitable gloves.
Chemical protection gloves are suitable, which are tested according to EN 374.
-Other protection measures:
Wash hands thoroughly after handling.
-Environmental exposure controls:
Use appropriate container to avoid environmental contamination.
Keep away from drains, surface and ground water.



HANDLING and STORAGE of ETHYLHEXYL PALMITATE:
-Precautions for safe handling:
*Recommendations:
Use local and general ventilation.
Use only in well-ventilated areas.
-Advice on general occupational hygiene:
Wash hands after use.
Do not eat, drink and smoke in work areas.
Remove contaminated clothing and protective equipment before entering eating areas.
Never keep food or drink in the vicinity of chemicals.
Never place chemicals in containers that are normally used for food or drink.
-Conditions for safe storage, including any incompatibilities:
*Packaging compatibilities:
Only packagings which are approved may be used.



STABILITY and REACTIVITY of ETHYLHEXYL PALMITATE:
-Chemical stability:
The material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.
-Possibility of hazardous reactions:
No known hazardous reactions.
-Conditions to avoid:
There are no specific conditions known which have to be avoided.



SYNONYMS:
Hexadecanoic acid 2-ethylhexyl ester
Octyl palmitate
2-ETHYLHEXYL PALMITATE
29806-73-3
2-Ethylhexyl hexadecanoate
Elfacos EHP
Hexadecanoic acid, 2-ethylhexyl ester
Ceraphyl 368
Wickenol 155
Palmitic acid, 2-ethylhexyl ester
EINECS 249-862-1
AI3-31580
UNII-2865993309
EC 249-862-1
2- ethylhexyl palmitate
2 - ethylhexyl palmitate
SCHEMBL15529
DTXSID3027958
Palmitic acid 2-ethylhexyl ester
Palmitic acid-2-ethylhexyl ester
(2-ETHYLHEXYL) PALMITATE
ETHYLHEXYL PALMITATE [INCI]
(+/-)-ETHYLHEXYL PALMITATE
ETHYLHEXYL PALMITATE [VANDF]
MFCD00072255
ETHYLHEXYL PALMITATE [WHO-DD]
AKOS016010384
ETHYLHEXYL PALMITATE, (+/-)-
AS-15135
LS-101204
CS-0063978
E1435
FT-0709066
D97727
EN300-1719134
A876381
J-017652
Hexadecanoic acid, 2-ethylhexyl ester (Palmitic acid, 2-ethylhexyl ester)
Hexadecanoic acid, 2-ethylhexyl esterOctyl palmitate
2-ETHYLHEXYL PALMITATE
OCTYL PALMITATE
ETHYL HEXYL PALMITATE
HEXADECANOIC ACID OCTYL ESTER
wickenol155
ceraphyl368
EVERNOL EHP
Elfacos EHP
OCTYL PALMITAE
octyl Plmitate
2-Ethylhexyl Hexadecanoate
Palmitic Acid 2-Ethylhexyl Ester
Hexadecanoic Acid 2-Ethylhexyl Ester
ISOOCTYL PALMITATE
Isooctyl hexadecanoate
Palmitic acid, 6-methylheptyl ester
Palmitic acid 2-ethylhexyl ester
6-methylheptyl hexadecanoate
Palmitic acid isooctyl
2-EHP
Isooctyl palmitate



ETHYLHEXYL PALMITATE
ETHYLHEXYL PALMITATE ETHYLHEXYL PALMITATE Ethylhexyl Palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid. It is an alternate to silicone-based ingredients offering a ‘dry-slip' feel. It helps adjust consistency in skin-care products. ETHYLHEXYL PALMITATE is classified as : Emollient Perfuming CAS Number 29806-73-3 EINECS/ELINCS No: 249-862-1 COSING REF No: 33890 Chem/IUPAC Name: Hexadecanoic acid, 2-ethylhexyl ester; Octyl palmitate Ethylhexyl Palmitate What Is Ethylhexyl Palmitate? Ethylhexyl Palmitate, also called Octyl Palmitate, is a clear, colorless, practically odorless liquid. Cetyl Palmitate is a white, crystalline, wax-like substance. Isopropyl Palmitate is a colorless, almost odorless, liquid. In cosmetics and personal care products, the Palmitates are used in a wide spectrum of products. Why is Ethylhexyl Palmitate used in cosmetics and personal care products? The Palmitate ingredients act as lubricants on the skin's surface, which gives the skin a soft and smooth appearance. Isopropyl Palmitate may be used as a binder which is an ingredient added to compounded dry powder mixtures of solids to provide adhesive qualities during and after compression to make tablets or cakes. Scientific Facts: The Palmitates are produced using palmitic acid, a naturally occurring fatty acid found in plants and animals, along with smaller amounts of other fatty acids. Cetyl Palmitate also occurs naturally as a chief constituent of spermaceti (wax from sperm whale oil) and can be found in staghorn coral. Ethylhexyl palmitate Ethylhexyl palmitate Ethylhexyl palmitate.png Names IUPAC name Hexadecanoic acid 2-ethylhexyl ester Other names Octyl palmitate Identifiers CAS Number 29806-73-3 check 3D model (JSmol) Interactive image ChemSpider 8649628 check ECHA InfoCard 100.045.314 PubChem CID 10474217 UNII 2865993309 check CompTox Dashboard (EPA) DTXSID3027958 Properties Chemical formula C24H48O2 Molar mass 368.646 g·mol−1 Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Ethylhexyl palmitate, or octyl palmitate, is the fatty acid ester derived from 2-ethylhexanol and palmitic acid. Ethylhexyl palmitate is commonly used in cosmetic formulations. Chemical structure Ethylhexyl palmitate is a branched saturated fatty ester derived from ethylhexyl alcohol and palmitic acid. Physical properties Ethylhexyl palmitate is a clear, colorless liquid at room temperature with a slightly fatty odor. Palmitic acid and 2-ethylhexanol are reacted in the presence of an acid catalyst to make the ester. Uses Ethylhexyl palmitate is used in cosmetic formulations as a solvent, carrying agent, pigment wetting agent, fragrance fixative and emollient. Its dry-slip skinfeel is similar to some silicone derivatives. ETHYLHEXYL PALMITATE Benefits of ethylhexyl palmitate: Non-occlusive emollient that provides a silky feel in various skin and hair care products Medium spreading Can replace mineral oil in formulations Use: Can be added to formulas as is, add to oil phase, use level 2-50%. Storage: Stable when kept in a closed container at a cool & dry place. For external use only. Applications: Color cosmetics, pressed powders, skin care product, sun care products. Raw material source: 2-ethylhexanol and palmitic acid Manufacture: Esterification of palmitic acid and 2-ethylhexanol to form an ester Animal Testing: Not animal tested GMO: Not tested for GMOs but very unlikely to contain GMOs Vegan: Does not contain animal-derived components. What Is It? Ethylhexyl Palmitate, also called Octyl Palmitate, is a clear, colorless, practically odorless liquid. Cetyl Palmitate is a white, crystalline, wax-like substance. Isopropyl Palmitate is a colorless, almost odorless, liquid. In cosmetics and personal care products, the Palmitates are used in a wide spectrum of products. Why is it used in cosmetics and personal care products? The Palmitate ingredients act as lubricants on the skin's surface, which gives the skin a soft and smooth appearance. Isopropyl Palmitate may be used as a binder which is an ingredient added to compounded dry powder mixtures of solids to provide adhesive qualities during and after compression to make tablets or cakes. Scientific Facts: The Palmitates are produced using palmitic acid, a naturally occurring fatty acid found in plants and animals, along with smaller amounts of other fatty acids. Cetyl Palmitate also occurs naturally as a chief constituent of spermaceti (wax from sperm whale oil) and can be found in staghorn coral. Is Ethylhexyl Palmitate Comedogenic? Ethylhexyl Palmitate is highly comedogenic. It means that if this ingredient is present in any product, it is very likely to cause pimples on acne prone skin. Even if your skin does not break out easily, you need be careful with products containing this ingredient. Ethylhexyl palmitate, or octyl palmitate, is the fatty acid ester derived from 2-ethylhexanol and palmitic acid. Ethylhexyl palmitate is commonly used in cosmetic formulations. Ethylhexyl palmitate is a branched saturated fatty ester derived from ethylhexyl alcohol and palmitic acid. Ethylhexyl palmitate is used in cosmetic formulations as a solvent, carrying agent, pigment wetting agent, fragrance fixative and emollient. Its dry-slip skinfeel is similar to some silicone derivatives. Description: Ester of 2-ethylhexanol and palmitic acid. Synonym: Octyl Palmitate. Saponification value 130 - 160. Clear amber liquid. Insoluble in water, miscible in oils. ven if a single ingredient such as Ethylhexyl Palmitate in a skincare or cosmetic / makeup product is comedogenic, that becomes its weakest link, rendering the product as a whole comedogenic. Manually checking an ingredient list for the presence of comedogenic ingredients can be tiresome. A free online tool anyone can use to find out instantly if a skincare or makeup product contains comedogenic or acnegenic ingredients. With Skingredients, you can also check if a single ingredient like Ethylhexyl Palmitate is comedogenic. There is also a smartphone version of Acne Mantra Skingredients. Get Skingredients on your Android smartphone. Depending on your Acne Prone Skin Type (1, 2 or 3), an ingredient may block your pores more or less depending on its comedogenicity. You need to be aware of these acne causing ingredients that may cause or aggravate acne. Is Ethylhexyl Palmitate Comedogenic? Ethylhexyl Palmitate is highly comedogenic. It means that if this ingredient is present in any product, it is very likely to cause pimples on acne prone skin. Even if your skin does not break out easily, you need be careful with products containing this ingredient. Comedogenic ingredients are pore-clogging and can cause breakouts. Even if a single ingredient such as Ethylhexyl Palmitate in a skincare or cosmetic / makeup product is comedogenic, that becomes its weakest link, rendering the product as a whole comedogenic. Manually checking an ingredient list for the presence of comedogenic ingredients can be tiresome. Enter Acne Mantra Skingredients, a free online tool anyone can use to find out instantly if a skincare or makeup product contains comedogenic or acnegenic ingredients. With Skingredients, you can also check if a single ingredient like Ethylhexyl Palmitate is comedogenic. Depending on your Acne Prone Skin Type (1, 2 or 3), an ingredient may block your pores more or less depending on its comedogenicity. You need to be aware of these acne causing ingredients that may cause or aggravate acne. Many comedogenic cosmetic ingredient lists rate comedogenic ingredients on a scale of 1-5, with 5 being the most comedogenic. In real life, comedogenicity does not vary at such a fine scale. You are better off using a more practical scale such as non-comedogenic, mildly comedogenic and highly comedogenic. Ethylhexyl Palmitate is not known to be irritating to the skin. Skin irritants may cause acne even if they are not pore-clogging. This is because they irritate the skin causing it to produce more sebum which may result in acne. Ethylhexyl Palmitate is mainly used as an emollient, perfuming agent in cosmetic products. Ethylhexyl palmitate is an ingredient that is used to improve the texture, feel, and the scent of skincare and cosmetic products. It functions as an emollient, solvent, and fragrance fixative. Ethylhexyl palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid. 2-ethylhexyl alcohol can be found in natural plant fragrances and also synthetically produced. Palmitic acid is the most common saturated fatty acid found in animals, plants and microorganisms, and is a major component of palm oil. Ethylhexyl palmitate is a clear, colorless liquid at room temperature with a slightly fatty odor. It is insoluble in water but mildly dissolves in oils. Why Is Ethylhexyl Palmitate Used? In cosmetics and skincare products, ethylhexyl palmitate functions as an emollient, solvent, and fragrance fixative. Moisture As an emollient, ethylhexyl palmitate helps to keep the skin moist and supple by reducing water loss from the top layers of the skin. Emollients also act as lubricants by reducing friction when anything rubs against the skin. Ethylhexyl palmitate is considered to be a non-occlusive emollient, which means it does not form a film on the surface of the skin. It is often used as an organic replacement to silicones in a cosmetic formulation because it provides a dry-slip, silky feel that is very similar to how a silicone would feel. While all skin types can benefit from emollients like ethylhexyl palmitate, emollients are very beneficial for those who have dry, rough, and/or flaky skin. Emollients can treat these symptoms, leaving the skin looking and feeling soft and smooth. In addition, emollients may be suitable for those that suffer from conditions such as eczema, psoriasis, or other inflammatory skin conditions. Solvent Ethylhexyl palmitate functions as a solvent by helping other ingredients dissolve. Solvents can also increase the efficacy of active ingredients in a formulation by enhancing their absorption through the skin. Appearance Another function of ethylhexyl palmitate in cosmetics is as a pigment wetting agent. Wetting agents work by reducing the interfacial tension between two different types of ingredients in a cosmetic formulation. Wetting agents are useful in makeup as they improve the pigment or color distribution in the formulation. Think about even eyeshadow or foundation pigment. Fragrance Lastly, ethylhexyl palmitate functions as a fragrance fixative in cosmetics and skincare products. A fixative helps to equalize the volatile fragrance components making them last longer and remain more stable on the skin. Is Ethylhexyl Palmitate Safe? The safety of ethylhexyl palmitate and other alkyl esters has been assessed by the Cosmetic Ingredient Review Expert Panel, a group that evaluates the safety of skincare and cosmetic ingredients. In their findings, the Expert Panel was able to determine that ethylhexyl palmitate doesn't show any evidence of toxicity or irritation. It does produce some very mild eye irritation in higher concentrations, usually outside the concentrations used in skincare and cosmetic products. The Expert Panel concluded that ethylhexyl palmitate and other alkyl esters were safe as cosmetic ingredients. Palmitic acid and 2-Ethylhexanol are reacted in the presence of an acid catalyst to make 2-Ethylhexyl palmitate (CAS NO.16958-85-3). It also can be synthesized by using aminosulfonic acid as catalyst under the condition of reduced pres- sure. Instead of aminosulfonic acid, the enzyme can also be used as a catalyst such as the lipase from Candida sp. 99-125. After it is immobilized on surfactant modified cotton membrane, it can be used to prepare the 2-Ethylhexyl palmitate . ethylhexyl palmitate Rating: GOOD Categories: Emollients, Texture Enhancer Mixture of a fatty alcohol and palmitic acid that functions as an emollient and texture enhancer. There’s no research indicating this ingredient, which may be synthetic, plant-, or animal-derived, is a problem for skin. Ethylhexyl Palmitate Why Is Ethylhexyl Palmitate Used In Skincare? Ethylhexyl palmitate is an ingredient that is used to improve the texture, feel, and the scent of skincare and cosmetic products. It functions as an emollient, solvent, and fragrance fixative. Ethylhexyl palmitate is an ester of 2-ethylhexyl alcohol and palmitic acid. 2-ethylhexyl alcohol can be found in natural plant fragrances and also synthetically produced. Palmitic acid is the most common saturated fatty acid found in animals, plants and microorganisms, and is a major component of palm oil. Ethylhexyl palmitate is a clear, colorless liquid at room temperature with a slightly fatty odor. It is insoluble in water but mildly dissolves in oils. Ethylhexyl palmitate THE GOOD:As an emollient, ethylhexyl palmitate can help reduce the appearance of dry flaky skin. Ethylhexyl palmitate is also used to improve the texture and sensory feel of formulations. THE NOT SO GOOD:Can produce eye irritation in high concentrations. However, those concentrations are not in the scope of skincare products. WHO IS IT FOR?All skin types except those that have an identified allergy to it. SYNERGETIC INGREDIENTS:Works well with most ingredients KEEP AN EYE ON:Nothing to keep an eye on here. Why Is Ethylhexyl Palmitate Used? In cosmetics and skincare products, ethylhexyl palmitate functions as an emollient, solvent, and fragrance fixative. Moisture As an emollient, ethylhexyl palmitate helps to keep the skin moist and supple by reducing water loss from the top layers of the skin. Emollients also act as lubricants by reducing friction when anything rubs against the skin. Ethylhexyl palmitate is considered to be a non-occlusive emollient, which means it does not form a film on the surface of the skin. It is often used as an organic replacement to silicones in a cosmetic formulation because it provides a dry-slip, silky feel that is very similar to how a silicone would feel. While all skin types can benefit from emollients like ethylhexyl palmitate, emollients are very beneficial for those who have dry, rough, and/or flaky skin. Emollients can treat these symptoms, leaving the skin looking and feeling soft and smooth. In addition, emollients may be suitable for those that suffer from conditions such as eczema, psoriasis, or other inflammatory skin conditions. Solvent Ethylhexyl palmitate functions as a solvent by helping other ingredients dissolve. Solvents can also increase the efficacy of active ingredients in a formulation by enhancing their absorption through the skin. Appearance Another function of ethylhexyl palmitate in cosmetics is as a pigment wetting agent. Wetting agents work by reducing the interfacial tension between two different types of ingredients in a cosmetic formulation. Wetting agents are useful in makeup as they improve the pigment or color distribution in the formulation. Think about even eyeshadow or foundation pigment. Fragrance Lastly, ethylhexyl palmitate functions as a fragrance fixative in cosmetics and skincare products. A fixative helps to equalize the volatile fragrance components making them last longer and remain more stable on the skin. Is Ethylhexyl Palmitate Safe? The safety of ethylhexyl palmitate and other alkyl esters has been assessed by the Cosmetic Ingredient Review Expert Panel, a group that evaluates the safety of skincare and cosmetic ingredients. In their findings, the Expert Panel was able to determine that ethylhexyl palmitate doesn’t show any evidence of toxicity or irritation. It does produce some very mild eye irritation in higher concentrations, usually outside the concentrations used in skincare and cosmetic products. The Expert Panel concluded that ethylhexyl palmitate and other alkyl esters were safe as cosmetic ingredients.
ETHYLHEXYL PALMITATE ( Palmitate d'octyle) Palmitate d'octyle ( Octyl palmitate)
ETHYLHEXYL PELARGONATE, N° CAS : 59587-44-9. Nom INCI : ETHYLHEXYL PELARGONATE. Nom chimique : 2-Ethylhexyl nonanoate. N° EINECS/ELINCS : 261-819-9. Ses fonctions (INCI), Emollient : Adoucit et assouplit la peau
ETHYLHEXYL PELARGONATE
ETHYLHEXYL POLYHYDROXYSTEARATE, N° CAS : 1423155-00-3. Nom INCI : ETHYLHEXYL POLYHYDROXYSTEARATE. Ses fonctions (INCI). Emollient : Adoucit et assouplit la peau, Agent d'entretien de la peau : Maintient la peau en bon état
ETHYLHEXYL POLYHYDROXYSTEARATE
ETHYLHEXYL SALICYLATE. N° CAS : 118-60-5. Origine(s) : Synthétique. Nom INCI : ETHYLHEXYL SALICYLATE. Nom chimique : 2-Ethylhexyl salicylate. N° EINECS/ELINCS : 204-263-4 La concentration maximale autorisée en cosmétique est la suivante : 5 %.. Ses fonctions (INCI). Absorbant UV : Protège le produit cosmétique contre les effets de la lumière UV. Filtre UV : Permet de filtrer certains rayons UV afin de protéger la peau ou les cheveux des effets nocifs de ces rayons.
ETHYLHEXYL SALICYLATE
ETHYLHEXYL STEARATE, N° CAS : 22047-49-0, Nom INCI : ETHYLHEXYL STEARATE, N° EINECS/ELINCS : 244-754-0. Ses fonctions (INCI): Emollient : Adoucit et assouplit la peau; 22047-49-0 [RN]; 244-754-0 [EINECS]; 2-ethylhexyl octadecanoate; 2-Ethylhexyl stearate; 2-Ethylhexylstearat [German] ; ETHYLHEXYL STEARATE;Octadecanoic acid, 2-ethylhexyl ester [ACD/Index Name] Stéarate de 2-éthylhexyle [French] [22047-49-0] 2-Ethylhexyl stearate, mixture of stearate and palmitate (7:3) 2-Ethylhexyl stearate, mixture of stearate and palmitate (7:3), Technical grade 2-Ethylhexyloctadecanoate 2-ETHYLHEXYLSTEARATE ethyl 4-hydroxycyclohexane-1-carboxylate MFCD00072275 [MDL number] SCHEMBL153398 stearic acid, 2-ethylhexyl ester
ETHYLHEXYL SALICYLATE (OCTISALATE USP)
2-Ethylhexyl salicylate ,WMO;usafdo-11;Sunarome O;USAF do-11;EUSOLEX OS;OCTISALATE;Escalol 587;Uvinul O-18;Sunarome WMO;Dermoblock OS , shuiyangsuanyixinzhi;OCTYL SALICYLATE(OS);2-hydroxy-benzoicaci2-ethylhexylester;Benzoic acid, 2-hydroxy-, 2-ethylhexyl ester;Benzoicacid,2-hydroxy-,2-ethylhexylester;Ethylhexyl salicylate CAS No.118-60-5
ETHYLHEXYL STEARATE
2-Ethylhexyl stearate octadecanoic acid; 2-ethylhexyl ester 2-ethylhexyl octadecanoate cas no: 22047-49-0
ETHYLHEXYL STEARATE
Ethylhexyl stearate is again one member of the groups called stearate esters which are obtained by reacting stearic acid with an alkyl group containing alcohol.
Ethylhexyl stearate is a clear, almost colorless (or slightly yellowish) oily liquid (an ester to be precise) that's used as a medium spreading emollient.
Ethylhexyl stearate gives skin a nice and smooth after-feel and it's very good at reducing oiliness or greasiness coming from other heavier oils in the formula.

CAS Number: 22047-49-0
EC Number: 244-754-0
Molecular Formula: C26H52O2
Molecular Weight: 396.6899

22047-49-0 [RN] 244-754-0 [EINECS] 2-ethylhexyl octadecanoate 2-Ethylhexyl stearate [ACD/IUPAC Name] 2-Ethylhexylstearat [German] [ACD/IUPAC Name] ETHYLHEXYL STEARATE Octadecanoic acid, 2-ethylhexyl ester [ACD/Index Name] Stéarate de 2-éthylhexyle [French] [ACD/IUPAC Name] [22047-49-0] 2-Ethylhexyl stearate, mixture of stearate and palmitate (7:3) 2-Ethylhexyl stearate, mixture of stearate and palmitate (7:3), Technical grade 2-Ethylhexyloctadecanoate 2-ETHYLHEXYLSTEARATE AGN-PC-00L26C CHEMBL3184927 DSSToxCID27178 DSSToxGSID47178 DSSToxRID82175 ethyl 4-hydroxycyclohexane-1-carboxylate MFCD00072275 [MDL number] SCHEMBL153398 stearic acid, 2-ethylhexyl ester Octadecanoic acid, octyl ester [ACD/Index Name] octyl octadecanoate Octyl stearate [ACD/IUPAC Name] Octylstearat [German] [ACD/IUPAC Name] Stéarate d'octyle [French] [ACD/IUPAC Name] Stearic acid, octyl ester 22047-49-0 [RN] 244-754-0 [EINECS] 2-ethylhexyl octadecanoate 2-Ethylhexyl stearate [ACD/IUPAC Name] 2-Ethylhexylstearat [German] [ACD/IUPAC Name], ETHYLHEXYL STEARATE, Octadecanoic acid, 2-ethylhexyl ester [ACD/Index Name], Stéarate de 2-éthylhexyle [French] [ACD/IUPAC Name], [22047-49-0] [RN], 2-Ethylhexyl stearate, mixture of stearate and palmitate (7:3), 2-Ethylhexyloctadecanoate, 2-ETHYLHEXYLSTEARATE, AGN-PC-00L26C, CHEMBL3184927, DSSToxCID27178, DSSToxGSID47178, DSSToxRID82175, ethyl 4-hydroxycyclohexane-1-carboxylate, MFCD00072275 [MDL number], SCHEMBL153398, stearic acid, 2-ethylhexyl ester, 2-Ethylhexyl stearate, 22047-49-0, 2-Ethylhexyl octadecanoate, Ethylhexyl stearate, Cetiol 868, Octadecanoic acid, 2-ethylhexyl ester, EG3PA2K3K5, DTXSID9047178, Stearic acid, 2-ethylhexyl ester, C26H52O2, ethyl hexyl stearate, CRODAMOL OS, TEGOSOFT OS, ETHOX EHS, PELEMOL OS, EXCEPARL EH-S, UNII-EG3PA2K3K5, SCHEMBL153398, ?2-ETHYLHEXYL STEARATE, ESTOL 1545, CHEMBL3184927, DTXCID7027178, OPJWPPVYCOPDCM-UHFFFAOYSA-N, ETHYLHEXYL STEARATE [INCI], Tox21_302619, ETHYLHEXYL STEARATE [WHO-DD], MFCD00072275, AKOS015901877, NCGC00256861-01, CAS-22047-49-0, CS-0152204, FT-0756635, E78095, EC 244-754-0, W-110539, Q27277167, OCTADECANOIC ACID, 2-ETHYLHEXYL ESTER, (+/-)-, 2-Ethylhexyl stearate, mixture of stearate and palmitate (4:6)

Ethylhexyl stearate is commonly used as an emollient to deliver skin-softening properties and a smooth afterfeel.
Ethylhexyl stearate is a medium spreading emollient for all kind of cosmetic applications.

Ethylhexyl stearate or octyl stearate is an ester of stearic acid with octanol.
Ethylhexyl stearate is again one member of the groups called stearate esters which are obtained by reacting stearic acid with an alkyl group containing alcohol.

Stearate esters all have unique properties of oily nature, but low viscosity and lighter feel.
That’s why they are the choice of solvents in makeup related products.

Ethylhexyl stearate is obtained from various animal and plant source.
Ethylhexyl stearate comes as clear to slightly yellowish liquid.

Ethylhexyl stearate, also known as 2-Ethylhexyl stearate or Octyl Stearate, is a renewable palm derivative with a variety of uses in both personal care and cosmetics manufacturing.
Ethylhexyl stearate is a stearate ester with similar properties to Isopropyl Myristate.
As with all stearate personal care esters, the Ethylhexyl stearate manufacturing process entails a reaction between Ethylhexyl stearate and alcohols such as cetyl, butyl, isopropyl or myristyl alcohol.

Ethylhexyl stearate is a fatty acid derived from animal fat.
Ethylhexyl stearate acts as a lubricant that softens the skin and gives Ethylhexyl stearate a smooth appearance.

Ethylhexyl stearate is excellent liquid emollient and thickening agent for cosmetic formulations.
Ethylhexyl stearate provides a soft barrier to the skin to impart moisturization and a smooth feel.

Ethylhexyl stearate is a clear, almost colorless (or slightly yellowish) oily liquid (an ester to be precise) that's used as a medium spreading emollient.
Ethylhexyl stearate gives skin a nice and smooth after-feel and it's very good at reducing oiliness or greasiness coming from other heavier oils in the formula.

Ethylhexyl stearate is used an emollient derived from plant oil that prevents water loss
Ethylhexyl stearate is also known as Octyl Stearate

Ethylhexyl stearate also known as 2-Ethylhexyl Octadecanoate or Octyl stearate is a palm derivative which is renewable in nature and is extensively used in personal care industry.
The stearate esters are prepared by the reaction between Ethylhexyl stearate and alcohol such as isopropyl, ethylhexyl, myistyl alcohol, cetyl, butyl among others.

Ethylhexyl stearate can be obtained form from animal origin as well as vegetable fats.
Ethylhexyl stearate is prepared by the reaction between Ethylhexyl stearate and ethylhexyl alcohol.

Ethylhexyl stearate is a clear ester liquid which is free of suspended matter and is available in colourless liquid form.
Ethylhexyl alcohol possess unique property of low viscosity and oily nature owing to which when applied on skin or lips Ethylhexyl stearate forms an hydrophobic film.
Thereby, softens the skin and imparts smooth appearance.

With rising consumer concern towards personal health, demand for personal care serices and products are witnessing a substantial growth.
Thereby, boosting the market growth of Ethylhexyl stearate is commonly used ester in personal care products.

Ethylhexyl stearate is commonly used as an emollient which prevents the water loss.
Hence, is extensively used as emulsion, bath oils and as solvent in cosmetic products.

Ethylhexyl stearate is widely used in the manufacturing of formulations for skin make up, lipstick, eye liner and other skin care products.
Apart from personal care industry, Ethylhexyl stearate also widely used as an intermediate, lubricating agent and surface active agent.

Owing to these properties ethtylhexyl stearate is commonly used in the manufacturing of metal working fluids.
Also, Ethylhexyl stearate offers good thermal stability and hence finds application in aluminium rolling, also is used in manufacturing of ink additives and paints.
Hence, broad spectrum of application provides an opportunistic platform for the robust growth of Ethylhexyl stearate market over the period of time.

Ethylhexyl stearate is a special emollient ester in cosmetic formulations.
Ethylhexyl stearate is a softening, thickening agent, dispersant and solvent.

Ethylhexyl stearate is often used as a base for skin care agents.
Ethylhexyl stearate is suitable for use in lotions, sunscreens, hair care, lip care, eye care, antiperspirant and bath oils.
Ethylhexyl stearate is oil soluble and supplied as a whitish clear liquid.

Ethylhexyl stearate, also known as 2-Ethylhexyl stearate or Octyl Stearate, is a renewable palm derivative that has a variety of uses in both personal care and cosmetic manufacturing.
Ethylhexyl stearate is a stearate ester with similar properties to Isopropyl Myristat.

As with all stearate personal care esters, the Ethylhexyl stearate manufacturing process causes a reaction between Ethylhexyl stearate and alcohols such as cetyl, butyl, isopropyl or myristyl alcohol.
Ethylhexyl stearate acts as a lubricant that softens the skin and gives Ethylhexyl stearate a smooth appearance.

Ethylhexyl stearate or Octyl stearate, is a date derivative that is renewable in nature and widely used in the personal care industry.
Stearate esters are prepared by the reaction between Ethylhexyl stearate and alcohol such as isopropyl, ethylhexyl, myistyl alcohol, cetyl, butyl, among others.

Ethylhexyl stearate can be obtained from vegetable oils as well as from animal origin.
Ethylhexyl stearate is prepared by the reaction between Ethylhexyl stearate and ethylhexyl alcohol.

Ethylhexyl stearate is a clear ester liquid with no suspended matter and available in colorless liquid form.
Ethylhexyl alcohol has a unique property of low viscosity and oily nature, as Ethylhexyl stearate forms a hydrophobic film when applied to the skin or lips.
Thus, Ethylhexyl stearate softens the skin and gives Ethylhexyl stearate a smooth appearance.

Ethylhexyl stearate is an excellent moisturizer with low comedogenicity and medium spreading properties.
Ethylhexyl stearate gives the skin a soft and smooth appearance while preventing water loss.
Ethylhexyl stearate is very suitable for use in sun screen formulations.

Ethylhexyl stearate is a renewable palm derivative with a variety of uses in both personal care and industrial applications.
Ethylhexyl stearate is used in cosmetic formulations as a solvent, carrying agent, wetting agent, emollient, and used mostly in the formulation of, eye/skin makeup, lipstick and skin care products.
Ethylhexyl stearate also widely used in metal working fluids, textile auxiliaries and lube & grease.

Ethylhexyl stearate is a chemical compound that belongs to the family of esters.
Ethylhexyl stearate is commonly used in various industries, including cosmetics, pharmaceuticals, and plastics.
This paper aims to provide a comprehensive review of Ethylhexyl stearate, including Ethylhexyl stearate method of synthesis or extraction, chemical structure, biological activity, biological effects, applications, future perspectives, and challenges.

Ethylhexyl stearate is a low odor product with resistance to extraction by water, oils and solvents.
Ethylhexyl stearate is the least effective costabilizer on Ethylhexyl stearate range due to Ethylhexyl stearate lower oxirane value but is good at reducing viscosity in plastisols and remains liquid down to -20°C.

Ethylhexyl stearate is used in cosmetics to provide a barrier between skin and the elements, and to soften and smooth the skin.
Ethylhexyl stearate used in cosmetics as a thickening agent and emollient.

Ethylhexyl stearate used as plasticizer for natural rubber and synthetic rubber.
Ethylhexyl stearate used as release agent.

Ethylhexyl stearate used as lubricating agent for process aluminium foil; creates plasticity.
Ethylhexyl stearate used in the pharmaceutical industry and in plastics; oil agent of textile; additive for leather.

Ethylhexyl stearate is a light ester with low viscosity (7-10,5 cSt) and emollient properties.
Ethylhexyl stearate improves the spreadability of preparations, Ethylhexyl stearate easily absorbed and leaves a non-greasy, non-occlusive protective film on the skin, which feels silky and smooth.
Ethylhexyl stearate is ideal on makeup formulations such as lipsticks and mascaras.

Ethylhexyl stearate is an ester of stearic acid and 2-ethylhexanol.
Ethylhexyl stearate is a clear, colorless liquid with a faint odor and a low viscosity.

The chemical formula of Ethylhexyl stearate is C26H52O2, and Ethylhexyl stearate has a molecular weight of 368.64 g/mol.
Ethylhexyl stearate is commonly used in the cosmetic industry as an emollient and a solvent.

As an emollient, Ethylhexyl stearate has a softening and smoothing effect on the skin and hair, making them feel less greasy and more comfortable.
As a solvent, Ethylhexyl stearate can dissolve other ingredients and help them spread more evenly on the skin or hair.
Ethylhexyl stearate is considered safe for use in cosmetics, and Ethylhexyl stearate low toxicity makes Ethylhexyl stearate an attractive ingredient for a variety of personal care products.

Ethylhexyl stearate is also known as Octyl stearate, Ethylhexyl stearate can be used as a lubricant in all kinds of cosmetic products.
Ethylhexyl stearate is an IPM alternative.
Ethylhexyl stearate has a medium-low lubrication feel.

Ethylhexyl stearate can be used in products where oiliness is not desired.
Ethylhexyl stearate will also reduce the oiliness of other oils.

Ethylhexyl stearate is a cream-type cleansing cosmetic compound containing large amount of oil phase and Ethylhexyl stearate manufacturing method.
In cosmetics and personal care products, stearate esters are used most frequently in the formulation of eye makeup, skin makeup, lipstick and skin care products.

Ethylhexyl stearate is used in personal care applications and and in can lubes.
Ethylhexyl stearate is a palm dervied product made from Stearic Acid and 2-Ethylhexanol.

Ethylhexyl stearate can be considered a protector of the skin.
Ethylhexyl stearate is an emollient derived from plant oil.

The lipide prevents water loss and therefore helps the skin to efficiently store moisture.
Ethylhexyl stearate is acts as a good moisturizer and emollient for skin creams, lotions and sunscreen.

Ethylhexyl stearate is a cationic polymerization that is used in the production of polyvinyl chloride.
Ethylhexyl stearate has been shown to be an effective additive for hydrophobic effects, and Ethylhexyl stearate has very high values for surface methodology.

Ethylhexyl stearate is also clinically proven to have skin cell penetration properties and can be used as a carrier agent for other ingredients.
The fatty acid portion of this molecule provides hydroxyl groups, which may help with the function of dimethyl fumarate.
Ethylhexyl stearate also contains a potassium hexafluorophosphate group in Ethylhexyl stearate structure, which can be used as an emulsifier or dispersant.

Ethylhexyl stearate is mainly a skin conditioning ingredient and Ethylhexyl stearate acts primarily as lubricant on the skin's surface, which gives the skin a soft and smooth appearance.
In our products, Ethylhexyl stearate is used as hair conditioner.
Ethylhexyl stearate helps to increase the softness and smoothness of hair, reduce tangles and surface roughness.

Use and Benefits of Ethylhexyl stearate:
Ethylhexyl stearate is also linked to skin’s natural fatty acid content, so Ethylhexyl stearate is ideal for skin preparation.
Moreover, Ethylhexyl stearate imparts the right amount of viscosity to Ethylhexyl stearate, Ethylhexyl stearate acts as a thickening agent as well.

Ethylhexyl stearate also forms a film over the skin, a hydrophobic barrier which does not let the moisture pass through and escape from the skin.
And without any greasy feel, Ethylhexyl stearate moisturizes the skin.

Ethylhexyl stearate also nourishes the skin and provides a protective barrier; moist skin is healthy enough to fight any external inflammation.
After regular application, resultant skin may become softer and smoother.
Ethylhexyl stearate is most frequently used in skincare products, lipstick, skin makeup, and eye makeup.

Ethylhexyl stearate is a surfactant with a wide variety of applications and can be found, for example, as a solvent in lubricants and lubricant additives, surface treatment agents.
The following consumer products may contain Ethylhexyl stearate: fabrics, textiles and leather products, detergents, dishwashing liquids, lubricants, oils (excluding food oils) and others.

Ethylhexyl stearate is often used as an emollient to prevent water loss.
For this reason, Ethylhexyl stearate is widely used as a solvent in emulsions, bath oils and cosmetic products.

Ethylhexyl stearate is widely used in the production of formulations for skin make-up, lipstick, eyeliner and other skin care products.
Besides the personal care industry, Ethylhexyl stearate is also used as an intermediate, lubricant and surfactant oris widely used.

Because of these properties, Ethylhexyl stearate is widely used in the production of metalworking fluids.
Ethylhexyl stearate also offers good thermal stability and therefore finds application in aluminum rolling, Ethylhexyl stearate is also used in the manufacture of ink additives and paints.
Therefore, Ethylhexyl stearate wide range of applications provides an opportunistic platform for the Ethylhexyl stearate market to grow strongly over time.

However, with the increasing demand for organic and natural personal care products, various natural-based ingredients are used in the production of personal care products.
Thus, Ethylhexyl stearate limits the market growth of Ethylhexyl stearate.

Moreover, Ethylhexyl stearate is derived from animal fat, which is hindering the growth of the Ethylhexyl stearate market with the increasing adoption of vegan-based products.
Ethylhexyl stearate also causes mild eye irritation and produces a mild odor, which may affect the adoption of ethyl stearate-based products among consumers.

Usage Areas of Ethylhexyl stearate:
Ethylhexyl stearate is used in cosmetic Softener, Dispersant, Solvent and Thickener.
Ethylhexyl stearate is used in metalworking lubricant.

Ethylhexyl stearate is branched chain softener ester specially developed for personal care and pharmaceutical applications.
Ethylhexyl stearate is non-occlusive with good spreading properties.

Ethylhexyl stearate is excellent super lubricant in detergent systems and soaps.
Ethylhexyl stearate is increases hair shine.
Ethylhexyl stearate is used in bath oils, skin cleansers, shampoos and conditioners.

Cosmetic use:
Ethylhexyl stearate is used in oil-based with low viscosity, high penetration and spreading effect.

Uses at industrial sites:
Ethylhexyl stearate is used in the following products: washing & cleaning products, metal surface treatment products, polymers, textile treatment products and dyes and pH regulators and water treatment products.
Ethylhexyl stearate is used for the manufacture of: textile, leather or fur.
Release to the environment of Ethylhexyl stearate can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid, as processing aid and as an intermediate step in further manufacturing of another substance (use of intermediates).

Industry Uses:
Lubricants and lubricant additives
Plating agents and surface treating agents
Solvents (which become part of product formulation or mixture)
Surface active agents
Emulsifier
Hydraulic fluids
Intermediate
Lubricants and lubricant additives
Lubricating agent
Other
Solubility enhancer
Surface modifier
Surfactant (surface active agent)

Consumer Uses:
Ethylhexyl stearate is used in the following products: washing & cleaning products, adhesives and sealants, lubricants and greases, polymers, textile treatment products and dyes, plant protection products, polishes and waxes and fertilisers.
Release to the environment of Ethylhexyl stearate can occur from industrial use: in the production of articles and in processing aids at industrial sites.
Other release to the environment of Ethylhexyl stearate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Other consumer Uses:
Fabric, textile, and leather products not covered elsewhere
Laundry and dishwashing products
Lubricants and greases
Non-TSCA use
Personal care products
Emulsifier
Hydraulic fluids
Intermediate
Lubricants and lubricant additives
Lubricating agent
Other
Solubility enhancer
Surfactant (surface active agent)

Applications of Ethylhexyl stearate:
Ethylhexyl stearate acts as a good moisturizer and emollient in personal care formulations like skin creams, lotions and sunscreens.
Ethylhexyl stearate is also finds use in color cosmetics like eyebrow pencil, concealer, lipstick etc.
Ethylhexyl stearate is used as an oil component for bath oils, bath emulsions, and as a solvent for active substances in cosmetics.

Ethylhexyl stearate is a variety of resin processing of the lubricant, non-toxic, with water resistance and good thermal stability.
Mainly used for PVC transparent soft and hard extrusion, injection molding, calendering products, the amount of 0.5-1 copies.

Ethylhexyl stearate of the modified vinyl chloride - vinyl acetate copolymer, polystyrene, nitrile rubber and other processing performance is also very effective.
Ethylhexyl stearate can also be used as a lubricant for fabrics, waterproofing agents, lubricants additives, cosmetics base material and so on.

Ethylhexyl stearate is a specialty emollient ester.
Ethylhexyl stearate is a superior emollient, thickening agent, dispersant, and solvent.

Ethylhexyl stearate properties allow use as a cleaner or diluent for lipophilic systems; cosmetic emollient and dispersant; plastic additive as external lubricant; industrial lubricant or separator; substitution of mineral, vegetable and selected silicone oils; and pigment binding and dispersing coagent.

Categories: Thickeners / Emulsifiers, Texture Enhancer, Softeners
Ethylhexyl stearate is often used as an emollient for Ethylhexyl stearate skin softening properties and smooth feel.

Ethylhexyl stearate is often used as the base for skin conditioning agents.
Suitable for use in lotions, sunscreens, hair care, lip care, eye care, antiperspirants, and bath oils.

Ethylhexyl stearates serve as intermediates, surface active agents and lubricants/lubricant additives.

Ethylhexyl stearate is functions include the following.
CASE: Paint and Ink Additive
Lube and Grease: Oil Base Fluid
Metal Working Fluids: Lubricant with Excellent Adhesion to Metals and Good Thermal Stability. Also Used in Aluminum Rolling
Plastics: Lubricant
Rubber: Processing Agent
Textiles: Oiling Agent
Personal Care: Thickening Agent, Skin Conditioning Agent and Emollient in Skin Care Products
Cosmetics: Used as a Base, a Thickening Agent, a Pigment Wetting Agent, a Dispersant, a Solvent and an Emollient in Skin and Eye Make-Up and in Lipstick.
Personal care products/cosmetics using Ethylhexyl stearate: Lipstick, eye makeup, skin care and makeup products, moisturizers, anti-wrinkle creams and lotions, anti-aging products, hair conditioners and styling products, baby lotions and eye shadow

Industry Based Ethylhexyl stearate Applications:
Personal care
Textile
Chemicals

Applications of Ethylhexyl stearate based on functionality:
Lubrication
Processing
Darkening
Distributor

Other Applications:
After sun
Baby Care and Cleaning
Body care
Color Care
Facial Facial
Personal Cleaner
Care Wipes
Self Tanning
Sun protection
Bath, Shower & Soaps
Eye Colour
Face / Neck Skin Care
Face Colour
Facial Cleansers
Hair Conditioners - Rinse off
Lip Colour
Shampoos
Sun Protection
Tanning

Method of Synthesis or Extraction of Ethylhexyl stearate:
Ethylhexyl stearate can be synthesized by the esterification of stearic acid with 2-ethylhexanol.
The reaction is catalyzed by an acid catalyst, such as sulfuric acid or p-toluenesulfonic acid.

The efficiency and yield of this method depend on the reaction conditions, such as temperature, pressure, and reaction time.
The yield of this method is typically high, ranging from 80% to 95%.
However, this method may have environmental and safety considerations, such as the use of hazardous chemicals and the generation of waste.

Chemical Structure and Biological Activity of Ethylhexyl stearate:
Ethylhexyl stearate has a chemical formula of C24H48O2 and a molecular weight of 368.64 g/mol.
Ethylhexyl stearate is a colorless to pale yellow liquid with a faint odor.

Ethylhexyl stearate has been shown to have various biological activities, including anti-inflammatory, antioxidant, and antimicrobial activities.
Ethylhexyl stearate acts by inhibiting the production of pro-inflammatory cytokines, scavenging free radicals, and disrupting the cell membrane of microorganisms.

Biological Effects of Ethylhexyl stearate:
Ethylhexyl stearate has been shown to have potential therapeutic effects on various diseases, such as acne, psoriasis, and atopic dermatitis.
Ethylhexyl stearate can improve skin hydration, reduce skin irritation, and enhance the penetration of active ingredients.

However, Ethylhexyl stearate may also have potential toxic effects, such as skin sensitization, eye irritation, and reproductive toxicity.
The toxicity of Ethylhexyl stearate depends on the dose, exposure route, and duration.

General Manufacturing Information of Ethylhexyl stearate:

Industry Processing Sectors:
All Other Chemical Product and Preparation Manufacturing
Computer and Electronic Product Manufacturing
Electrical Equipment, Appliance, and Component Manufacturing
Fabricated Metal Product Manufacturing
Machinery Manufacturing
Miscellaneous Manufacturing
Oil and Gas Drilling, Extraction, and Support activities
Petroleum Lubricating Oil and Grease Manufacturing
Printing Ink Manufacturing
Printing and Related Support Activities
Soap, Cleaning Compound, and Toilet Preparation Manufacturing
Textiles, apparel, and leather manufacturing
Transportation Equipment Manufacturing

Functions of Ethylhexyl stearate:
According to Chemiplast, a Belgian researcher, Ethylhexyl stearate is used as an oil component for emulsions, bath oils, and as a solvent for active substances in cosmetics.
Stearate esters are used most frequently in the formulation of eye makeup, skin makeup, lipstick and skin care products.

Properties of Ethylhexyl stearate:
Ethylhexyl stearate is a clear liquid ester that is free of suspended matter, although Ethylhexyl stearate may also be a waxy solid.
Colorless in its liquid form, Ethylhexyl stearate produces a faint odor.

Ethylhexyl stearate is soluble in many organic solvents, although Ethylhexyl stearate is insoluble in water and Ethylhexyl stearate can also dissolve other substances.
When applied to the skin, Ethylhexyl stearate will leave a thin coating upon drying.
Ethylhexyl stearate also reduces the thickness of lipsticks.

Storage of Ethylhexyl stearate:
Ethylhexyl stearate at normal temperatures and provide adequate ventilation.
Keep Ethylhexyl stearate from contacting oxidizing agents and observe all local regulations regarding safe product disposal.

Safety of Ethylhexyl stearate:
The Ethylhexyl stearate safety sheet indicates this chemical product is not hazardous.
However, Ethylhexyl stearate can cause irritation to the eyes or when ingested, although Ethylhexyl stearate is unlikely to cause skin irritation.
Ethylhexyl stearate will remain stable under typical handling and working conditions.

Safety Measures/Side Effects:
The CIR Expert Panel notes that the safety of the stearate esters has been assessed in a number of studies.
They have low acute oral toxicity and are essentially non-irritating to the eyes.
At cosmetic use concentrations, the stearate esters were, at most, minimally irritating to skin.

Identifiers of Ethylhexyl stearate:
CAS No.: 22047-49-0
Chemical Name: 2-ETHYLHEXYL STEARATE
CBNumber: CB8120607
Molecular Formula: C26H52O2
Molecular Weight: 396.69
MDL Number: MFCD00072275

Properties of Ethylhexyl stearate:
Appearance @ 20°C: Clear to light yellow liquid
Acid value (MGKOH/G): 1 Maximum
Saponification value: 142-156
Iodine value (WIJS): 1 Maximum
Hydroxyl value (MGKOH/G): 3 Maximum
Refractive index @ 25°C: 1.445-1.448
Specific gravity @25°C: 0.850-0.860

Density: 0.86g/cm3
Boiling Point: 438.7ºC at 760mmHg
Molecular Formula: C26H52O2
Molecular Weight: 396.69000
Flash Point: 225.6ºC
Exact Mass: 396.39700
PSA: 26.30000
LogP: 9.15160
Vapour Pressure: 6.79E-08mmHg at 25°C
Index of Refraction: 1.451

Boiling point: 420.33°C (rough estimate)
Density: 0.8789 (rough estimate)
vapor pressure: 0Pa at 20℃
refractive index: 1.4563 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Hexanes (Slightly)
form: Oil
color: Colourless
Specific Gravity: 0.826
InChI: InChI=1S/C26H52O2/c1-4-7-9-10-11-12-13-14-15-16-17-18-19-20-21-23-26(27)28-24-25(6-3)22-8-5-2/h25H,4-24H2,1-3H3
InChIKey: OPJWPPVYCOPDCM-UHFFFAOYSA-N
SMILES: C(OCC(CC)CCCC)(=O)CCCCCCCCCCCCCCCCC
LogP: 11.994 (est)

Molecular Weight: 396.7 g/mol
XLogP3-AA: 11.7
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 23
Exact Mass: 396.396730897 g/mol
Monoisotopic Mass: 396.396730897 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Count: 28
Complexity: 314
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Related Products of Ethylhexyl stearate:
(2'S)-Nicotine 1-Oxide-d4
rac-Nicotine 1-Oxide-d4
1,7-Dimethyl-1H-imidazo[4,5-g]quinoxalin-2-amine
Disulfoton Sulfone
Disulfoton

Names of Ethylhexyl stearate:

IUPAC names:
2-ethylhexyl octadecanoate
2-Ethylhexyl Stearate
2-Ethylhexyl stearate
2-ethylhexyl stearate
2-ethylhexyl stearate
LINCOL 60 LINCOL OS
octadecanoic acid, 2-ethylhexyl ester
Octadecanoic acid, 2-ethylhexyl ester + Hexadecanoic acid, 2-ethylhexyl ester
octyl octadecanoate
Viscostatic E20
Ethylhexyl Triazone
benzoic acid, 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-, tris(2-ethylhexyl) ester; octyl triazone; ethyl hexyl triazone CAS NO:88122-99-0
ETHYLHEXYLGLYCERIN
ETHYLHEXYLGLYCERYL PALMITATE. Nom INCI : ETHYLHEXYLGLYCERYL PALMITATE. Nom chimique : Hexadecanoic Acid, 3-[(2-Ethylhexyl)Oxy]-2-Hydroxypropyl Ester. Ses fonctions (INCI) Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile). Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
ETHYLHEXYLGLYCERYL PALMITATE
3-Methyloctan-3-ol; Amylethylmethylcarbinol; 2-Ethyl-2-heptanol cas no: 5340-36-3
ETHYLHEXYLTRIAZONE
ETHYLHEXYL TRİAZONE; ethylhexyl triazone; benzoic acid, 4,4',4''-(1,3,5-triazine-2,4,6-triyltriimino)tris-, tris(2-ethylhexyl) ester; ethyl hexyl triazone; octyl triazone CAS NO:88122-99-0
ETHYLOCTINOL
paraben / PAO / parahydroxybenzoate, Inci : Ethylparaben, Cas : 120-47-8, 4-hydroxybenzoate d'éthyle, éthylparabène, parahydroxybenzoate d'éthyl, Le 4-hydroxybenzoate d'éthyle ou éthylparabène (E2144) est un conservateur5 de la famille des parabènes. Il est utilisé dans les cosmétiques, les médicaments et les aliments, pour ses propriétés antibactériennes et antifongiques.4-hydroxybenzoic acid, ethyl ester; Ethyl 4-hydroxybenzoate; Ethylparaben; Benzoic acid, 4-hydroxy-, ethyl ester; ETHYL PARABEN
ETHYLPARABEN
Ethylparaben;ETHYL 4-HYDROXYBENZOATE; 120-47-8; Ethyl paraben; Ethyl p-hydroxybenzoate CAS NO: 120-47-8
ETHYLPARABEN
Ethylparaben is an ethyl ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with ethanol.
Ethylparaben is widely used as an antimicrobial preservative in cosmetics, food products, and pharmaceutical formulations.
Ethylparaben may be used either alone or in combination with other paraben esters or with other antimicrobial agents.

CAS Number: 120-47-8
Molecular Formula: C9H10O3
Molecular Weight: 166.17
EINECS Number: 204-399-4

Synonyms: , CHEMBL15841, ETHYLPARABEN [USP-RS], Ethyl parahydroxybenzoate (TN), ethyl 4-hydroxybenzenecarboxylate, CHEBI:31575, AMY5118, NSC8510, Ethyl parahydroxybenzoate (JP17), HMS2091E17, Parahydroxybenzoic acid ethyl ester, Pharmakon1600-01400151, 4-hydroxy benzoic acid ethyl ester, HY-B0934, NSC-8510, NSC23514, Tox21_111961, Tox21_300335, BBL012166, BDBM50428380, NSC755851, s4525, STK070911, ETHYL HYDROXYBENZOATE [MART.], AKOS000120512, ETHYL HYDROXYBENZOATE [WHO-DD], ETHYL HYDROXYBENZOATE [WHO-IP], Tox21_111961_1, CCG-213682, CS-4403, DB13628, ETHYL PARAHYDROXYBENZOATE [JAN], NSC-755851, NCGC00160654-02, NCGC00160654-03, NCGC00160654-04, NCGC00160654-06, NCGC00254462-01, AC-11586, AC-34532, AS-11988, DA-73229, NCI60_041866, SBI-0206674.P002, ETHYL ESTER OF P-HYDROXYBENZOIC ACID, E0884, ETHYLIS HYDROXYBENZOAS [WHO-IP LATIN], H0211, NS00008316, EN300-16106, D01647, Ethyl 4-hydroxybenzoate, ReagentPlus(R), 99%, ETHYL PARAHYDROXYBENZOATE [EP IMPURITY], ETHYL PARAHYDROXYBENZOATE [EP MONOGRAPH], W18471, AB00375765_03, A804518, Q229976, SR-05000001552, SR-05000001552-1, W-108475, BRD-K02464583-001-01-4, BRD-K02464583-001-02-2, Ethyl 4-hydroxybenzoate, SAJ first grade, >=99.0%, PROPYL HYDROXYBENZOATE IMPURITY C [EP IMPURITY], Z53833636, Ethyl 4-hydroxybenzoate, Vetec(TM) reagent grade, 99%, Ethylparaben, certified reference material, TraceCERT(R), F0728-0009, METHYL PARAHYDROXYBENZOATE IMPURITY B [EP IMPURITY], Ethylparaben, United States Pharmacopeia (USP) Reference Standard, Ethyl parahydroxybenzoate, European Pharmacopoeia (EP) Reference Standard, Ethylparaben, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H

Ethylparaben is a member of the class of compounds known as parabens.
It has a role as an antimicrobial food preservative, an antifungal agent, a plant metabolite and a phytoestrogen.
Ethylparaben is a paraben and an ethyl ester.

In cosmetics it is one of the most frequently used preservatives.
The parabens are effective over a wide pH range and have a broad spectrum of antimicrobial activity, although they are most effective against yeasts and molds.
Owing to the poor solubility of the parabens, paraben salts, particularly the sodium salt, are frequently used.

However, this may cause the pH of poorly buffered formulations to become more alkaline.
Ethylparaben (ethyl para-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid.
Its formula is HO-C6H4-CO-O-CH2CH3.

Ethylparaben is a chemical compound commonly used as a preservative in cosmetics, pharmaceuticals, and food products.
Ethylparaben is a member of the paraben family, which consists of esters of p-hydroxybenzoic acid.
Ethylparaben is known for its antimicrobial properties, which help to prevent the growth of harmful bacteria and mold, thereby extending the shelf life of products.

Ethylparaben is used as an antifungal preservative. As a food additive.
Sodium ethyl para-hydroxybenzoate, the sodium salt of ethylparaben, has the same uses and is given the E number E215.
Over the past 10 years parabens have become criticised and condemned for use in cosmetics due to their alleged relation to health concerns affecting women and men.

The research about parabens is conflicting and polarising.
Some research indicates they are safe as used in cosmetics and are preferred over other preservatives to keep a formula stable.
These studies also showed Ethylparaben did not have any effect when compared to natural hormones in the body.

However, other research has concluded they are indeed problematic: Some studies determined a 100% concentration of parabens caused skin samples (meaning not intact skin on a person) to break down.
However, these studies don’t apply to the tiny amount (1% or less) of parabens typically used in cosmetics.
In low amounts, Ethylparaben were not shown to harm skin; in fact, they offer a benefit due to their ability to thwart the growth of mold, fungi, and harmful pathogens.

Other studies casting Ethylparaben in a negative light were based on force-feeding them to rats, a practice that is not only cruel but unrelated to what happens when parabens are applied to skin.
There are studies indicating absorption of parabens through skin associated with application of skin care products, but those studies did not take into consideration that parabens are still used as food-grade preservatives or found naturally in plants and that could have been the source not the cosmetics.
Ethylparaben is used in lotions, creams, shampoos, and makeup products to prevent microbial contamination.

Acts as a preservative in various pharmaceutical formulations, including topical creams and ointments.
Utilized in food products to inhibit the growth of mold and yeast, though its use is regulated in many countries.
Ethylparaben, like other parabens, has been scrutinized for potential health risks.

Some studies have suggested a link between parabens and endocrine disruption, leading to regulatory review and restrictions on their concentrations in consumer products.
Regulatory agencies like the FDA (Food and Drug Administration) and the European Commission have set guidelines and limits for the use of Ethylparaben in products to ensure consumer safety.
Ethylparaben is in the paraben family of preservatives used by the food, pharmaceutical, and personal care product industries.

Parabens mimic estrogen and can act as potential hormone (endocrine) system disruptors.
Ethylparaben is ethyl-4-hydroxybenzoate, a member of a family of alky esters of para-hydroxybenzoic acid differing by their chemical substituents on the benzene ring.
Ethylparaben occurs as a white or colourless powder or crystalline, odourless, and tasteless powder.

Ethylparaben is provided as delivered and specified by the issuing Pharmacopoeia.
All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Ethylparaben, ethyl, propyl, butyl, and heptyl esters of p-hydroxybenzoate are denominated parabens.
They are odorless, almost colorless crystals or white crystalline powders.
Water solubility is inversely related to alkyl chain length.

The pH range of antimicrobial activity is 3–8; their antimicrobial activity is mainly against bacteria and fungi.
Combinations of two or more parabens are often used since they have synergistic effects.
FDA sets the maximum level of application of methyl (21CFR184.1490) and propyl (21CFR184.1670) esters of p-hydroxybenzoic acid at 0.1%.

Ethylparaben is an ethyl ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with ethanol.
Ethylparaben has a role as an antimicrobial food preservative, an antifungal agent, a plant metabolite and a phytoestrogen.
Ethylparaben is a paraben and an ethyl ester.

Ethylparaben is a Standardized Chemical Allergen.
The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.
Ethylparaben is a natural product found in Ulva australis, Andrographis paniculata, and other organisms with data available.

Ethylparaben is the ethyl ester of p-hydroxybenzoic acid.
Ethylparaben's formula is HO-C6H4-CO-O-CH2CH3.
Ethylparaben is a member of the class of compounds known as parabens.

Ethylparaben is used as an antifungal preservative.
Sodium ethyl para-hydroxybenzoate, the sodium salt of ethylparaben, has the same uses and is given the E number E214.
Ethyl paraben is an ethyl ester.

Ethylparaben has a role as an antimicrobial food preservative, an antifungal agent, a plant metabolite and a phytoestrogen.
Ethylparaben is produced naturally and found in several fruits and insects, where it acts as an antimicrobial agent.
Ethylparaben is mainly used as antiseptics in cosmetics, food and medicine (E number E214).

Ethylparaben is also can be used as feed preservatives and antiseptic for bacteria.
Ethylparaben is readily absorbed from the gastrointestinal tract or through the skin.
Ethylparaben is hydrolyzed to p-hydroxybenzoic acid and rapidly excreted in urine without accumulating in the body.

Under the Federal Food, Drug, and Cosmetic Act (FD&C Act), cosmetic products and ingredients, other than color additives, do not need FDA approval before they go on the market.
Broad concentration ranges reported in each product category in 1981 were < 0.1% and > 0.1% to 1%.
Studies show the in vivo estrogenicity of MP and EP at human exposure levels, and indicate that populations exposed to large amounts of MP and EP may have a high burden of
estrogenicity-related diseases.

Ethylparaben is an ethyl ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with ethanol.
Ethylparaben has a role as an antimicrobial food preservative, an antifungal agent, a plant metabolite and a phytoestrogen.
It is a paraben and an ethyl ester.

Ethylparaben is widely used as an antimicrobial preservative in cosmetics,food products, and pharmaceutical formulations.
Ethylparaben may be used either alone or in combination with other paraben esters or with other antimicrobial agents.
In cosmetics it is one of the most frequently used preservatives.

The parabens are effective over a wide pH range and have a broad spectrum of antimicrobial activity, although they are most effective against yeasts and molds.
Owing to the poor solubility of the parabens, paraben salts, particularly the sodium salt, are frequently used.
However, this may cause the pH of poorly buffered formulations to become more alkaline.

Ethylparaben is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative and food additive.
Ethylparaben is a standardized chemical allergen.
The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.

A very common type of feared-by-everyone-mostly-without-scientific-reason paraben.
Ethylparaben's a cheap, effective and well-tolerated ingredient to make sure the cosmetic formula does not go wrong too soon.

Ethylparaben is the ethyl ester of p-hydroxybenzoic acid, used as an antifungal preservative and food additive.
It is a standardized chemical allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.

These are aromatic compounds containing a benzoic acid, which is esterified with an alkyl group and para-substituted with a hydroxyl group.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Ethylparabens are a group of controversial preservatives that include butylparaben, isobutylparaben, propylparaben, methylparaben, and ethylparaben.

All of these were at one time the most widely used group of preservatives used in cosmetics.
Ethylparabens were so popular because of their gentle, non-sensitizing, and highly effective profile in comparison to other preservatives but also because they were derived naturally from plants, a rare phenomenon for a preservative.
Ethylparabens are found in plants in the form of p-hydroxybenzoic acid (PHBA), a chemical that breaks down to become parabens for a plants own protection.

Melting point: 114-117 °C (lit.)
Boiling point:297-298 °C (lit.)
Density: 1.1708 (rough estimate)
vapor pressure: 0.00012 hPa (25 °C)
refractive index: 1.5286 (estimate)
Flash point: 297-298°C
storage temp.: 2-8°C
solubility: Very slightly soluble in water, freely soluble in ethanol (96 per cent) and in methanol.
form: Crystalline Powder
pka: 8.31±0.13(Predicted)
color: White
PH: 4.5-5.5 (H2O, 20°C) (saturated solution)
Odor: at 100.00?%. mild phenolic
Water Solubility: Slightly soluble in water.
Merck: 14,3837
BRN: 1101972
Stability: Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.
LogP: 2.470

Ethylparaben, like other parabens, can enter the environment through wastewater.
There is some concern about its persistence and potential effects on aquatic life.
Ethylparaben works by inhibiting the growth of bacteria, mold, and yeast.

Ethylparaben disrupts microbial cell membrane functions, leading to the death of these organisms.
This antimicrobial action is effective at very low concentrations, which makes Ethylparaben a cost-effective preservative.
There are concerns that parabens can mimic estrogen and potentially disrupt hormonal balance.

However, the levels used in consumer products are generally considered safe by regulatory authorities.
Ongoing research continues to evaluate the safety, efficacy, and environmental impact of Ethylparaben.
Investigating potential links to cancer, reproductive issues, and other health concerns.

Exploring natural preservatives and novel antimicrobial technologies.
Ethylparaben is a paraben and preservative found in many skin care products, ranging from skin cream to body lotion to deodorant.

Ethylparaben can be found in essential oils used to treat dry skin and in primrose oil serving as an anti-septic.
Although parabens are generally considered safe when used in low percentages (.04% - .08%), a study claimed to have found a link between parabens and breast cancer.

According to the Cosmetic Ingredient Review (CIR) Expert Panel, however, "the available acute, subchronic, and chronic toxicity tests, using a range of exposure routes, demonstrate a low order of parabens' toxicity at concentrations that would be used in cosmetics" (source).
After testing different levels of exposure to parabens in women, men, and children, the CIR Expert Panel found that these "determinations are conservative and likely represent an overestimate of the possibility of an adverse effect (e.g., use concentrations may be lower, penetration may be less) and support the safety of cosmetic products in which parabens preservatives are used."

Parabens are a group of controversial preservatives that include butylparaben, isobutylparaben, propylparaben, methylparaben, and ethylparaben.
All of these were at one time the most widely used group of preservatives used in cosmetics. Parabens were so popular because of their gentle, non-sensitizing, and highly effective profile in comparison to other preservatives but also because they were derived naturally from plants, a rare phenomenon for a preservative.

Ethylparaben are found in plants in the form of p-hydroxybenzoic acid (PHBA), a chemical that breaks down to become parabens for a plants own protection.
Over the past 10 years parabens have become criticized and condemned for use in cosmetics due to their alleged relation to health concerns affecting women and men.
The research about parabens is conflicting and polarizing.

Some research indicates they are safe as used in cosmetics and are preferred over other preservatives to keep a formula stable.
These studies also showed parabens did not have any effect when compared to natural hormones in the body.
However, other research has concluded they are indeed problematic: Some studies determined a 100% concentration of parabens caused skin samples (meaning not intact skin on a person) to break down.

However, these studies don’t apply to the tiny amount (1% or less) of parabens typically used in cosmetics.
In low amounts, parabens were not shown to harm skin; in fact, they offer a benefit due to their ability to thwart the growth of mold, fungi, and harmful pathogens.
Other studies casting Ethylparaben in a negative light were based on force-feeding them to rats, a practice that is not only cruel but unrelated to what happens when parabens are applied to skin.

There are studies indicating absorption of parabens through skin associated with application of skincare products, but those studies did not take into consideration that Ethylparaben are still used as foodgrade preservatives or found naturally in plants and that could have been the source not the cosmetics.
The antimicrobial properties of ethylparaben are considerably reduced in the presence of nonionic surfactants as a result of micellization.

Absorption of ethylparaben by plastics has not been reported, although it appears probable given the behavior of other parabens.
Ethylparaben is coabsorbed on silica in the presence of ethoxylated phenols. Yellow iron oxide, ultramarine blue, and aluminum silicate extensively absorb ethylparaben in simple aqueous systems, thus reducing preservative efficacy.
Ethylparaben is discolored in the presence of iron and is subject to hydrolysis by weak alkalis and strong acids.

Included in the FDA Inactive Ingredients Database (oral, otic, and topical preparations).
Included in nonparenteral medicines licensed in the UK.
Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Ethylparaben is the ethyl ester of paraben and is used as an antifungal preservative and food additive.
The solubility of Ethylparaben increases greatly as the temperature of the water rises.
Therefore a concentrate may be made up by heating an appropriate quantity of water to 60- 100 °C prior to addition of Ethylparaben.

This concentrate may then be added to the formulation, provided that the ester concentration does not exceed its solubility in the formulation at normal ambient temperatures.
Dissolving in organic solvents Ethylparaben is readily soluble in polar organic solvents.
Where such a solvent is already part of a formulation an Ethylparaben concentrate may be made up prior to addition.

If a suitable solvent is not already part of the formulation,a highly concentrated solution may be madeup e.g. 32% in Ethanol, which would give insignificant residual levels of ethanol in the end product.
Ethylparaben is readily soluble in lipophilic ingredients and may be introduced to a formulation by adding to the oil phase with some warming before any emulsification stage.

In multiphase systems, such as emulsions, Ethylparaben is often advisable to use a combination of aqueous dissolution with either of the other methods to ensure adequate preservation.
The ester may be incorporated in the water to its maximum solubility and any further quantities may be dissolved in the oil phase, or solvent, as appropriate.
Some individuals may experience allergic reactions to parabens, though such cases are relatively rare.

FDA (Food and Drug Administration): In the United States, Ethylparaben is generally recognized as safe (GRAS) for use in food, drugs, and cosmetics, within specified concentration limits.
EU (European Union): The European Commission allows the use of Ethylparaben in cosmetics but has set maximum concentration limits to ensure safety.

The Scientific Committee on Consumer Safety (SCCS) has conducted reviews and provided guidelines on safe levels of use.
Various countries have their own regulations and guidelines regarding the use of parabens, often aligning with international standards.

Storage:
Aqueous ethylparaben solutions at pH 3–6 can be sterilized by autoclaving, without decomposition.
At pH 3–6, aqueous solutions are stable (less than 10% decomposition) for up to about 4 years at room temperature, while solutions at pH 8 or above are subject to rapid hydrolysis (10% or more after about 60 days at room temperature).
Ethylparaben should be stored in a well-closed container in a cool, dry place.

Uses:
Ethylparaben is used as a food preservative to extend the shelf life of various food products by inhibiting the growth of bacteria, mold, and yeast.
Beyond its use in consumer products, Ethylparaben finds applications in industrial settings.
Ethylparaben to prevent microbial growth and extend the shelf life of these products.

As a preservative in various chemical formulations used in these industries.
Ethylparaben is also used in laboratory settings for research purposes.
As a reference standard in studies investigating the effects of parabens on health.

In the development and validation of analytical methods for detecting parabens in various matrices.
Ethylparaben is used in certain veterinary products to ensure their safety and efficacy by preventing microbial contamination.
Syrups and suspensions for veterinary use.

Ethylparaben is a key ingredient in many personal care products because it prevents microbial contamination, which can cause spoilage and pose health risks to consumers.
Ethylparaben to keep formulations free from bacteria and fungi.

Ethylparaben preserves the shelf life of products like foundations, powders, and blushes.
Ethylparaben is used in shampoos, conditioners, and styling gels to maintain product integrity.
Included in facial and body washes to prevent microbial growth.

In pharmaceuticals, maintaining sterility and preventing contamination is crucial for patient safety.
Ethylparaben is used in: Topical Medications: Creams and ointments applied to the skin, Oral Solutions: Syrups and liquid suspensions taken by mouth.
Ethylparaben is used in formulations that require stringent microbial control.

Ethylparaben helps extend the shelf life of various food items by preventing the growth of mold and bacteria.
Cakes, pastries, and bread where moisture content can promote microbial growth.
Ethylparaben, have been scrutinized for their potential to disrupt hormone function by mimicking estrogen.

This has raised concerns about possible links to breast cancer and reproductive toxicity.
Although rare, some individuals may experience skin irritation or allergic reactions to parabens.
The FDA considers Ethylparaben as generally recognized as safe (GRAS) when used in specified amounts.

The European Commission has imposed limits on the concentration of parabens in cosmetic products.
The Scientific Committee on Consumer Safety (SCCS) has reviewed and provided guidelines on their safe use.
Different countries have varying regulations, often aligned with those of major regulatory bodies like the FDA and EU.

Ethylparaben, like other parabens, can enter the environment through wastewater.
Studies are ongoing to understand; Persistence: The longevity of Ethylparaben in environmental settings, Bioaccumulation: Potential for accumulation in aquatic organisms and the broader ecosystem impact.
Due to safety concerns and regulatory pressures, manufacturers are exploring alternatives to Ethylparaben.

These include; A common alternative with broad-spectrum antimicrobial activity, Effective against yeast and fungi.
Ethylparaben is used in food and cosmetics to inhibit mold and yeast growth.
Investigate the chronic effects of parabens on health and the environment.

Identify and develop safer, effective preservatives.
Enhance analytical techniques for detecting parabens in various products and environmental samples.
Ethylparaben is mainly used as antiseptics in cosmetics, food and medicine.

It is also can be used as feed preservatives and antiseptic for bacteria.
Ethylparaben is a preservative that is used in the formulation of cosmetics and personal care products in order to extend the shelf-life by preventing microbial contamination.
In most formulations, parabens are used at very low levels ranging from 0.01 to 0.3%.

Ethylparaben, a novel sorbent for solid-phase extraction, was used to study its retention property.
Ethylparaben has high extraction efficiency towards the compounds tested owing to the electrostatic interaction, hydrophobic interaction and hydrogen bonding.
Ethylparaben may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC).

These Secondary Standards are qualified as Certified Reference Materials.
These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Ethylparaben is widely used in cosmetic and personal care products to prevent microbial growth and extend shelf life.

Some specific applications include: Skin Care Products: Lotions, creams, moisturizers, and sunscreens, Hair Care Products: Shampoos, conditioners, hair gels, and styling products.
In the pharmaceutical industry, Ethylparaben serves as a preservative to ensure the stability and safety of various medications.

Ethylparaben applications include: Topical Preparations: Creams, ointments, gels, and lotions used for treating skin conditions, Syrups, suspensions, and tablets to prevent contamination and degradation.
Ethylparaben certain parenteral formulations may include Ethylparaben to maintain sterility.

Safety Profile:
Ethylparaben, in vivo, have also been reported to exhibit estrogenic responses in fish.
The WHO has set an estimated total acceptable daily intake for methyl-, ethyl-, and propylparabens at up to 10 mg/kg body-weight.

Ethylparaben and other parabens are widely used as antimicrobial preservatives in cosmetics, food products, and oral and topical pharmaceutical formulations.
Systemically, no adverse reactions to parabens have been reported, although they have been associated with hypersensitivity reactions.


Ethylparaben ( Paraoxybenzoate d’ethyle )
1,2-Ethylenediamine; 1,2-Diaminoethane; EDA; Ethane-1,2-diamine; Aethaldiamin (German); Aethylenediamin (German); 1,2-diaminoaethan (German) ; 1,2-Diamino-ethaan (Dutch); 1, 2-Diamino-Ethano (Italian); Dimethylenediamine; Ethyleendiamine (Dutch); Ethylene-diamine (French); β-Aminoethylamine; cas no:107-15-3
ETIL ASETAT
SYNONYMS Acetate d'ethyle;ACETATE, ETHYL;acetato de etilo;Acetic acid ethyl ester;Acetic acid, ester with EtOH;Acetic acid, ethyl ester;Acetic ether;Acetidin;Acetoxyethane CAS NO:141-78-6
ETILENDIAMIN-(EDA)
EUCALYPTOL, N° CAS : 470-82-6, Nom INCI : EUCALYPTOL. Nom chimique : 1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane; 1,8-Cineole. N° EINECS/ELINCS : 207-431-5. Ses fonctions (INCI), Dénaturant : Rend les cosmétiques désagréables. Principalement ajouté aux cosmétiques contenant de l'alcool éthylique,Tonifiant : Produit une sensation de bien-être sur la peau et les cheveux Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques
ETİLEN GLİKOL DİSTEARAT
SYNONYMS Glycol Distearate; Ethylene Glycol Dioctadecanoate;Octadecanoic Acid, 1,2-Ethanediyl Ester; Ethylene Dioctadecanoate; 1,2-Ethanediyl Octadecanoate; CAS NO:627-83-8
EUCALYPTOL
EUGENOL, N° CAS : 97-53-0 - Eugénol, Autre langue : Eugenolo, Nom INCI : EUGENOL, Nom chimique : Phenol, 2-methoxy-4-(2-propenyl)-, N° EINECS/ELINCS : 202-589-1, L'Eugénol est un composé aromatique phénolique présent naturellement notamment dans le clou de girofle. Il sert à la fabrication de la vanilline et est utilisé dans les cosmétiques en tant qu'aromatisant. Il est employé en dentisterie en tant qu'analgésique, est utilisé dans les ciments chirurgicaux et certaines pâtes dentaires.Ses fonctions (INCI) : Dénaturant : Rend les cosmétiques désagréables. Principalement ajouté aux cosmétiques contenant de l'alcool éthylique. Tonifiant : Produit une sensation de bien-être sur la peau et les cheveuxAgent parfumant : Utilisé pour le parfum et les . matières premières aromatiques. Noms français : 1-HYDROXY-2-METHOXY-4-ALLYLBENZENE 1-HYDROXY-2-METHOXY-4-PROP-2-ENYLBENZENE 2-METHOXY-4-(2-PROPENYL) PHENOL 2-METHOXY-4-PROP-2-ENYLPHENOL 4-ALLYL-1-HYDROXY-2-METHOXYBENZENE 4-Allyl-2-Methoxybenzene 4-ALLYL-2-METHOXYPHENOL 4-ALLYLGUAIACOL ALLYLGUAIACOL CARYOPHILLIC ACID EUGENIC ACID Eugénol Hydroxy-1 méthoxy-2 allyl-4 benzène P-ALLYLGUAIACOL P-EUGENOL PHENOL, 2-METHOXY-4-(2-PROPENYL)- PHENOL, 4-ALLYL-2-METHOXY- Noms anglais : Eugenol Utilisation et sources d'émission Agent de saveur, agent anesthésiant
EUCALYPYOL
EUCALYPYOL = 1,8 CINEOLE

Eucalyptol is naturally produced cyclic ether and monoterpenoid.
Eucalyptol is an ingredient in many brands of mouthwash and cough suppressant.
Eucalyptol is an effective treatment for nonpurulent rhinosinusitis.

CAS Number: 470-82-6
EC Number: 207-431-5
Chemical Formula: C10H18O
Molar Mass: 154.249 g/mol

Eucalyptol is a type of monoterpenoid.
Eucalyptol occurs as a colorless liquid that exists as a bicyclic ether.

Eucalyptol also has a fresh, mint-like smell and a spicy-cooling taste.
Eucalyptol is insoluble in water.

However, Eucalyptol is miscible with organic solvents.
Typically, Eucalyptus makes up about 90% of the eucalyptus oil.

Moreover, eucalyptol forms crystalline adducts along with hydrohalic acid, o-cresol, resorcinol, phosphoric acid, etc.
The formation of these adducts is very important in purification.

The chemical formula of this compound is C10H18O.
Eucalyptol molar mass is 154.249 g/mol.

The density of this liquid is closely similar to that of water, and Eucalyptol has a low melting point, which is about 2.9 degrees Celsius.
But Eucalyptol boiling point is comparatively high, which is around 177 degrees Celsius.

Eucalyptol has a pleasant, spicy aroma and taste, and we can use Eucalyptol for flavoring, fragrance, and cosmetics.
We can use Eucalyptol oily form sparingly in different products such as baked goods, confectionery, meat products, and beverages.
Moreover, eucalyptol is an ingredient in commercially available mouthwashes, and Eucalyptol is useful in traditional medicine as a cough suppressant.

1,8-Cineole also known as Eucalyptol, belongs to the class of organic compounds known as oxanes.
Oxanes are compounds containing an oxane (tetrahydropyran) ring, which is a six-membered saturated aliphatic heterocycle, composed of one oxygen atom and five carbon atoms.

Eucalyptol is an organic compound that is a colourless liquid.
Eucalyptol is a cyclic ether and a monoterpenoid.

Monoterpenoids are terpenes that contain 10 carbon atoms and are comprised of two isoprene units.
The biosynthesis of monoterpenes is known to occur mainly through the methyl-eritritol-phosphate (MEP) pathway in the plastids.

Geranyl diphosphate (GPP) is a key intermediate in the biosynthesis of cyclic monoterpenes.
GPP undergoes several cyclization reactions to yield a diverse number of cyclic arrangements.

Eucalyptol is a natural constituent of a number of aromatic plants and their essential oil fractions.
Eucalyptus oil is the oil extracted from the leaves of various Eucalyptus species.

Eucalyptol oil is used for Eucalyptol aromatic properties and as an ingredient in pharmaceutical and industrial applications.
Cineole-based eucalyptus oil is used as a flavouring at low levels (0.002%) in various products, including baked goods, confectionery, meat products, and beverages.

Eucalyptol was given GRAS (Generally Recognized as Safe) status by the Flavor and Extract Manufacturer's Association FEMA in 1965 and is approved by the Food and Drug Administration for food use.
1,8-Dihydroxy-10-carboxy-p-menthane, 2-hydroxy-cineole, and 3-hydroxy-cineole are the main metabolites of eucalyptol.

Toxicological data available on eucalyptol is rather limited.
Following accidental exposure, death was reported in two cases after ingestion of 3.5-5 mL of essential eucalyptus oil, but a number of recoveries have also been described for much higher amounts of oil.

In a 1994 report released by five top cigarette companies, eucalyptol was listed as one of the 599 additives to cigarettes.
Eucalyptol is added to improve the flavour.
Eucalyptol is found in many foods, some of which are common thyme, caraway, sunflower, and pot marjoram.

Eucalyptol is an aromatic chemical, usually appearing as a clear liquid with a herbal eucalyptus odour.
Eucalyptol is naturally present as an organic compound in the essential oils of many plants, including tea tree, rosemary and sage.

Eucalyptol is the chief component of eucalyptus (Eucalyptus globulus) oil, and is used as a component of many fragrances, food and medicine flavourings for Eucalyptol potent aroma and minty-cooling flavour.
Eucalyptol is naturally present as a component of many of the essential oils we use as fragrances for our products.

Eucalyptol, commonly called cineole, is the primary terpene found in eucalyptus and this terpene got Eucalyptol name through eucalyptus.
More than 80% eucalyptol is present in the essential oil extracted from eucalyptus trees.

A good quantity of eucalyptol is present in tea trees, mugwort, bay leaves and cannabis.
The formula for eucalyptol is C10H18O and Eucalyptol can be topically applied to the body.

When compared to the other commonly found terpenes, eucalyptol has more conditions and features.
Eucalyptol can be directly applied on the skin, gums and other areas.

Eucalpytol can be orally inhaled, eaten or consumed as a tincture.
Like any other chemicals eucalyptol is toxic and dangerous when taken in higher dose, so Eucalyptol is always better to dilute the strength of the oil.

Eucalyptol controls airway mucus hypersecretion and asthma via anti-inflammatory cytokine inhibition.
Eucalyptol reduces inflammation and pain when applied topically.

Eucalyptol is a monoterpenoid.
A colorless liquid, Eucalyptol is a bicyclic ether.

Eucalyptol has a fresh mint-like smell and a spicy, cooling taste.
Eucalyptol is insoluble in water, but miscible with organic solvents.

Eucalyptol makes up ~70–90% of eucalyptus oil.
Eucalyptol forms crystalline adducts with hydrohalic acids, o-cresol, resorcinol, and phosphoric acid.
Formation of these adducts is useful for purification.

In 1870, F. S. Cloez identified and ascribed the name "eucalyptol" to the dominant portion of Eucalyptus globulus oil.

Eucalyptol is also known by some other names such as: cineol, cineole, 1,8-cineol, 1,8-cineole, 1,8-epoxy-p-menthan, 1,8-oxido-p-menthan, limonenoxide, cajeputol, eucalyptole, 1,3,3-trimethyl-2-oxabicyclo[2,2,2]octane.
This is an active liquid, colorless at room temperature, Eucalyptol is found in nature.

In the essential oil of products with the common name eucalyptus oil, this active ingredient accounts for more than 90%.
That's why many people call Eucalyptol eucalyptus oil.

Eucalyptol is naturally produced cyclic ether and monoterpenoid.
Eucalyptol is an ingredient in many brands of mouthwash and cough suppressant.

Eucalyptol controls airway mucus hypersecretion and asthma via anti-inflammatory cytokine inhibition.
Eucalyptol is an effective treatment for nonpurulent rhinosinusitis.

Eucalyptol reduces inflammation and pain when applied topically.
Eucalyptol kills leukaemia cells in vitro.

Eucalyptol is a natural product found in Curcuma amada, Thryptomene saxicola, and other organisms with data available.
1,8-cineol is a colorless liquid with a camphor-like odor.

Eucalyptol, also frequently called 1,8-cineol, is the primary constituent of oil produced by Eucalyptus spp.
Eucalyptol is also found in tea tree (Melaleuca alternifolia) oil, Artemisia spp. (e.g., wormwood and sagebrush), and even Cannabis sativa.

French chemist François Stanislas Cloez isolated eucalyptol from Eucalyptus globulus in 1870.
Another Eucalyptusspecies, E. cloeziana, was named in his honor.

Because Eucalyptol’s Thanksgiving week, you might have guessed that eucalyptol has something to do with the holiday.
If so, you’d be right.

In addition to the species mentioned above, eucalyptol is an ingredient in many spices used to prepare the turkey day meal: bay leaf, cardamom, rosemary, and sage, to name a few.
Eucalyptol is a contributor to the wonderful aroma of holiday cooking.

Eucalyptol is also used as a flavor ingredient in oral hygiene products and cough suppressants.
Eucalyptol is safe to ingest in small quantities, but Eucalyptol is toxic in larger doses.
In 1981, M. Verma and C. E. Meloan found that eucalyptol in bay leaves is an effective cockroach repellent.

Patients with chronic diseases such as cardiovascular diseases, chronic respiratory diseases, and neurological diseases have been shown to benefit from treatments such as aromatherapy in addition to medication.
Most chronic diseases are caused by chronic inflammation and oxidative stress as well as harmful factors.

Eucalyptol (1,8-cineole), a terpenoid oxide isolated from Eucalyptus species, is a promising compound for treating such conditions as Eucalyptol has been shown to have anti-inflammatory and antioxidant effects in various diseases, including respiratory disease, pancreatitis, colon damage, and cardiovascular and neurodegenerative diseases.
Eucalyptol suppresses lipopolysaccharide (LPS)-induced proinflammatory cytokine production through the action of NF-κB, TNF-α, IL-1β, and IL-6 and the extracellular signal-regulated kinase (ERK) pathway, and reduces oxidative stress through the regulation of signaling pathways and radical scavenging.

The effects of eucalyptol have been studied in several cell and animal models as well as in patients with chronic diseases.
Furthermore, eucalyptol can pass the blood-brain barrier and hence can be used as a carrier to deliver drugs to the brain via a microemulsion system.
In summary, the various biological activities of eucalyptol such as Eucalyptol anti-inflammatory and antioxidant properties, as well as Eucalyptol physicochemical characteristics, make this compound a potentially important drug for the treatment of chronic diseases.

Eucalyptol is widely distributed in plants.
The main food sources are eucalyptus oil (up to 80% eucalyptol), the herbs and spices mugwort, sweet basil, rosemary, sage and cardamom and their essential oils.
Highest exposure from food is likely to arise from hard (cough) candy in which up to about 130 mg eucalyptol/kg or about 2000 mg eucalyptus oil/kg have been reported to be used.

Consumption of 10 g of hard candy containing 2000 mg eucalyptus oil/kg would result in an intake of up to 16 mg of eucalyptol, equivalent to 0.27 mg/kg bw for an adult of 60 kg.
A mean daily intake of eucalyptol from flavoured foodstuffs in France has been estimated to be 4.5 mg/person, equivalent to 0.075 mg/kg bw.

This exercise was based on use levels of eucalyptol provided by industry and took into account the market share of all food categories possibly flavoured by plants, extracts of plants or eucalyptus oil.
The food intake data were from the French survey on individual consumptions.

Uses of Eucalyptol:
In the field of medicine, Eucalyptol is used to make mouthwash and cough medicine.
Eucalyptol has an antiseptic effect on the respiratory tract.

Helps relieve sore throat, itchy throat effectively.
Eucalyptol is used as a flavoring and flavoring agent in cosmetics, confectionery and food.

Due to Eucalyptol pleasant aroma and taste.
In addition, people also use Eucalyptol to make insect repellent.

Eucalyptol is chief constituent of oil of eucalyptus.
Eucalyptol is used in pharmaceuticals (cough syrups and expectorants).

Eucalyptol also used as a flavoring agent, fragrance, disinfectant, and solvent.
Eucalyptus oil contains up to 70% eucalyptol.

Eucalyptol is fragrance and flavoring agent in foods, candies, cough drops, personal car products.

Eucalyptol is used pharmaceuticals (cough syrups, expectorants), flavoring, perfumery
Essential oils such as eucalyptol reduce plaque-related gingivitis.

Because of Eucalyptol pleasant, spicy aroma and taste, eucalyptol is used in flavorings, fragrances, and cosmetics.
Cineole-based eucalyptus oil is used as a flavouring at low levels (0.002%) in various products, including baked goods, confectionery, meat products, and beverages.

In a 1994 report released by five top cigarette companies, eucalyptol was listed as one of the 599 additives to cigarettes.
Eucalyptol is claimed to be added to improve the flavor.

Eucalyptol is an ingredient in commercial mouthwashes, and has been used in traditional medicine as a cough suppressant.

Therapeutic Uses:
Eucalyptol has mucolytic, bronchodilating and anti-inflammatory properties and reduces the exacerbation rate in patients suffering from COPD, as well as ameliorates symptoms in patients suffering from asthma and rhinosinusitis.
Based on these effects, we therefore postulated the hypothesis that patients with acute bronchitis would also benefit from therapy with Eucalyptol.

As part of a double-blind, placebo-controlled, multi-center-study, a total of 242 patients with confirmed acute bronchitis was randomly selected to participate.
Over a period of 10 days, all patients were administered 3 x 200 mg of Eucalyptol, or a respective placebo, per day.

The primary outcome measure was a Bronchitis Sum Score, which summarizes the relevant symptoms of acute bronchitis.
After 4 days of treatment Eucalyptol was notable, that the patient group treated with Eucalyptol, showed significantly more improvements of the bronchitis-sum-score than those of the placebo group.

The statistical significant difference of the individual outcome measures was especially underlined by the frequency of cough fits by p?=?0.0001 after 4 days.
The effects of Eucalyptol in the treatment of acute bronchitis were clearly measurable and could be proven after a treatment period of merely 4 days.
This study corroborates the fact that Eucalyptol actively and significantly reduces cough frequency after four days.

The clinical effects of mucolytics in patients with chronic obstructive pulmonary disease (COPD) are discussed controversially.
Eucalyptol is the main constituent of eucalyptus oil and mainly used in inflammatory airway diseases as a mucolytic agent.

We hypothesized that Eucalyptol known mucolytic, bronchodilating and anti-inflammatory effects as concomitant therapy would reduce the exacerbation rate and show benefits on pulmonary function tests as well as quality of life in patients with COPD.
In this double-blind, placebo-controlled multi-center-study we randomly assigned 242 patients with stable COPD to receive 200 mg of Eucalyptol or placebo 3 times daily as concomitant therapy for 6 months during winter-time.

The frequency, duration and severity of exacerbations were combined as primary outcome measures for testing as multiple criteria.
Secondary outcome measures included changes of lung function, respiratory symptoms and quality of life as well as the single parameters of the exacerbations.

Baseline demographics, lung function and standard medication of both groups were comparable.
During the treatment period of 6 months the multiple criteria frequency, severity and duration of exacerbations were significantly lower in the group treated with Eucalyptol in comparison to placebo.

Secondary outcome measures validated these findings.
Improvement of lung function, dyspnea and quality of life as multiple criteria were statistically significant relative to placebo.

Adverse events were comparable in both groups.
Concomitant therapy with Eucalyptol reduces exacerbations as well as dyspnea and improves lung function and health status.
This study further suggests Eucalyptol as an active controller of airway inflammation in COPD by intervening in the pathophysiology of airway inflammation of the mucus membrane.

Industry Uses:
Flavoring and nutrient
Fragrance

Consumer Uses:
Fragrance

Other Uses:
Eucalyptol exhibits insecticidal and insect repellent properties.

In contrast, eucalyptol is one of many compounds that are attractive to males of various species of orchid bees, which gather the chemical to synthesize pheromones.
Eucalyptol is commonly used as bait to attract and collect these bees for study.

One such study with Euglossa imperialis, a nonsocial orchid bee species, has shown that the presence of cineole (also eucalyptol) elevates territorial behavior and specifically attracts the male bees.
Eucalyptol was even observed that these males would periodically leave their territories to forage for chemicals such as cineole, thought to be important for attracting and mating with females, to synthesize pheromones.

Dosage and Administration of Eucalyptol:

For adults:

Oral medicine:
Adults and children 12 years of age and older take 1 tablet/time: 2 to 4 tablets a day or as directed by a physician.

Spray:
Open the protective cap vertically.
Then put your index finger on the nozzle tip, press 2-3 times in the air to break the inner protective film of the nozzle.

Gently insert the nozzle into the side of the nose.
Then quickly press the nozzle 2-3 times in each nostril.

Clean and dry the nozzle, then close the protective cap.
Note, do not use the medicine more than 4 weeks after opening.

Essential Oils:
Sprinkle a few drops on a handkerchief and inhale as required.
Inhale the vapors from the spilled oil droplets into the bowl of hot water 'inhale' and the moisture is inhaled.
Add 2-3 drops of oil to a cup of warm water (50 ° C) and drink while still warm, use 2 times a day.

Nasal spray:
Pour one teaspoon of medicine into a cup or glass of hot water 70 degrees C-80 degrees C cover the mouth of the cup or glass with a paper funnel.
Place the nose in the funnel.

Then carefully inhale the steam through your nose slowly and slowly while the water is still hot.
Continue to inhale until the vapor is gone.
3 times a day, 1 teaspoon of medicine each time.

Massage oil:
Massage the skin at the painful spot.

Cough in the chest:
Rub in front of the chest, neck, and back.

Indigestion, abdominal pain:
Rub the abdomen Cold and flu (you can put 5-10 drops of oil in 250 mL of hot water in a steamer and inhaler), runny nose, stuffy nose: Rub the temples, neck, back of the neck, nose.

Dizziness, headache, nausea:
Rub both temples, neck, philtrum, nose. For children The dosage form is not suitable for use in children under 12 years of age.
Do not use the inhaler in children under 6 years of age, children with a history of seizures or convulsions due to high fever.

Indications and contraindications of Eucalyptol:

Indications:
Eucalyptol is indicated for the treatment of some of the following cases:
Relieves some symptoms of nasal congestion, rhinitis, and common cold.

Use antiseptic for respiratory tract, teeth, mouth.
Treats runny nose, flu, cough, sore throat, helps relieve symptoms of mild muscle sprains and cramps.

Contraindications:
Eucalyptol is contraindicated in some of the following cases:
Children under 30 months of age or children with seizures due to high fever or a history of seizures.

Do not use in cases of hypersensitivity to any ingredient of the drug.
Eucalyptol should not be used in cases of cough due to asthma and when the patient has respiratory failure (due to the respiratory-suppressive properties of Eucalyptol).

Benefits of Eucalyptol:
Eucalyptol is an analgesic, antibacterial, relieves pain.
Eucalyptol acts as a good anti-fungal and reduces inflammation in systematic manner.

Eucalyptol slows down the growth of cancer cells in the human body and prevents problems of oxidation to other molecules in the body.
Eucalyptol is a colourless natural organic compound and is an ingredient in many brands of mouthwash and cough suppressant.

Eucalyptol is often taken to control mucus hyper secretion and asthma.
Eucalyptol has the power to kill leukaemia cells in vitro and can reduce inflammation when applied externally.
Eucalyptol is used for effective treatment of non-purulent sinusitis and widely used world over.

For Aromatherapy:
Eucalyptol is used in aromatherapy with a combination of eucalyptus oil, lavender, marjoram, rosemary and peppermint oils to reduce pain and depression in people with arthritis.
Chewing gum with eucalyptol present in Eucalyptol can reduce dental plaque in some people.

Eucalyptol is widely used from ancient times for stuffy nose, wounds, ulcers, burns, bleeding gums, acne, bladder diseases, fever, flu, and many more.
Eucalyptol is present in large amounts in a variety of plants used in the manufacture of cosmetics and similar products.

Eucalyptol can enhance blood circulation in human body and Eucalyptol produces cytokines and prostaglandins by stimulated monocytes in vitro.
Higher dose of Eucalyptol by inhalation through nose may result in irritation, nausea and vomiting.

List of plants that contain Eucalyptol:
Aframomum corrorima
Artemisia tridentata
Cannabis
Cinnamomum camphora, camphor laurel (50%)
Eucalyptus cneorifolia
Eucalyptus dives
Eucalyptus dumosa
Eucalyptus globulus
Eucalyptus goniocalyx
Eucalyptus horistes
Eucalyptus kochii
Eucalyptus leucoxylon
Eucalyptus largiflorens
Eucalyptus oleosa
Eucalyptus polybractea
Eucalyptus radiata
Eucalyptus rossii
Eucalyptus salmonophloia
Eucalyptus sideroxylon
Eucalyptus smithii
Eucalyptus staigeriana
Eucalyptus tereticornis
Eucalyptus viridis
Eucalyptus wandoo
Hedychium coronarium, butterfly lily
Helichrysum gymnocephalum
Kaempferia galanga, galangal, (5.7%)
Laurus nobilis, bay laurel, (45%)
Melaleuca alternifolia, tea tree, (0–15%)
Salvia lavandulifolia, Spanish sage (13%)
Turnera diffusa, damiana
Umbellularia californica, pepperwood (22.0%)
Zingiber officinale, ginger

Manufacturing Methods of Eucalyptol:
Eucalyptol is obtained from essential oils containing high levels of eucalyptol, such as Eucalyptus globulus (about 60%), by fractional distillation (170-180 °C) followed by separation of the product by solidification of the distillate.

By fractionally distilling eucalyptus oil followed by freezing.
The oil is imported from Spain, Portugal, and Austria.

1,8-Cineole is extracted exclusively from eucalyptus oils with a high 1,8-cineole content.
Various processes are used to separate Eucalyptol from the other terpenes, for example, treatment with H2SO4 in the cold, distillation in the presence of phenols, such as cresols or resorcinol, which form loose addition compounds, or by addition to beta-naphthol.

1,8-Cineole can also be enriched by rectification.
The yield is increased by gasification in the presence of a chromium-nickel catalyst.

Technical-grade 1,8-cineole with a purity of 99.6 - 99.8% is produced in Spain in large quantities by fractional distillation of Eucalyptus globulus Labill.
A product essentially free from other products can be obtained by crystallization of cineole-rich eucalyptus oil fractions.

General Manufacturing Information of Eucalyptol:

Industry Processing Sectors:
All Other Basic Organic Chemical Manufacturing
All Other Chemical Product and Preparation Manufacturing
Food, beverage, and tobacco product manufacturing
Soap, Cleaning Compound, and Toilet Preparation Manufacturing

1,8-cineole is produced only from natural sources as these are sufficiently inexpensive to make synthesis uneconomic.
Originally, Eucalyptol was produced from Cajeput oil, but the discovery of Eucalyptus globulus, the oil of which contains up to 95% 1,8-cineole, in 1788 led to the first commercial production from that source in 1854 in Australia, and then to Eucalyptols taking over as the dominant source.
Much of the oil is used per se and only about one-quarter of Eucalyptol is distilled to produce pure cineole.

The chief constituent of oil of eucalyptus; also found in essential oils of laurel, rosemary, and many other aromatic plants.

Handling and Storage of Eucalyptol:

Nonfire Spill Response:

SMALL SPILLS AND LEAKAGE:
If you spill this chemical, use absorbent paper to pick up all liquid spill material.
Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal.

Solvent wash all contaminated surfaces with alcohol followed by washing with a strong soap and water solution.
Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

STORAGE PRECAUTIONS:
You should store this chemical under refrigerated temperatures and away from mineral acids and bases.

Storage Conditions:

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Recommended storage temperature -20 °C.

First Aid Measures of Eucalyptol:

EYES:
First check the victim for contact lenses and remove if present.
Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center.

Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN:
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing.
Gently wash all affected skin areas thoroughly with soap and water.
If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION:
IMMEDIATELY leave the contaminated area.
Take deep breaths of fresh air.

If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital.
Provide proper respiratory protection to rescuers entering an unknown atmosphere.

Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
If not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION:
DO NOT INDUCE VOMITING.
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center.

Be prepared to transport the victim to a hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body.

DO NOT INDUCE VOMITING.
IMMEDIATELY transport the victim to a hospital.

Precautions when using Eucalyptol:
If the cough does not improve after being treated with the usual dose, do not increase the dose on your own.
Do not apply to eyes or open wounds.

Use with caution in patients with asthma and respiratory failure.

Ointment form:
Discontinue use as soon as burns or blisters appear.
Keep the medicine out of reach of children Never use the medicine after the expiry date or discolouration.

Caution should be exercised when administering the drug to women during pregnancy or lactation.
For medicines or supplements containing Eucalyptol, if you miss a dose, try to take Eucalyptol again as soon as possible.

However, if Eucalyptol is almost time for your next dose, take your next dose as usual.
Absolutely do not arbitrarily double the dose as directed.

With the diverse effects of the drug Eucalyptol, when using Eucalyptol, you need to be very careful to use Eucalyptol correctly to avoid possible unwanted side effects.
Please consult with your doctor to get the dose and method of use that is best for your condition.

Fire Fighting of Eucalyptol:
Fires involving this compound should be controlled with a dry chemical, carbon dioxide, foam or Halon extinguisher.

Fire Fighting Procedures of Eucalyptol:
Advice for firefighters; Wear self-contained breathing apparatus for firefighting if necessary.
Use water spray to cool unopened containers.

Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Isolation and Evacuation of Eucalyptol:
As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions.

LARGE SPILL:
Consider initial downwind evacuation for at least 300 meters (1000 feet).

FIRE:
If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Cleanup Methods of Eucalyptol:
Personal precautions, protective equipment and emergency procedures:
Use personal protective equipment.
Avoid breathing vapors, mist or gas.

Remove all sources of ignition.
Beware of vapors accumulating to form explosive concentrations.

Vapors can accumulate in low areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.

Methods and materials for containment and cleaning up:
Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations.

Disposal Methods of Eucalyptol:
Recycle any unused portion of the material for Eucalyptol approved use or return Eucalyptol to the manufacturer or supplier.

Ultimate disposal of the chemical must consider:
The material's impact on air quality; potential migration in air, soil or water; effects on animal, aquatic and plant life; and conformance with environmental and public health regulations.
If Eucalyptol is possible or reasonable use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.

Preventive Measures of Eucalyptol:

Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Identifiers of Eucalyptol:
CAS Number: 470-82-6
Beilstein Reference: 105109 5239941
ChEBI: CHEBI:27961
ChEMBL: ChEMBL485259
ChemSpider: 2656
DrugBank: DB03852
ECHA InfoCard: 100.006.757
EC Number: 207-431-5
Gmelin Reference: 131076
IUPHAR/BPS: 2464
KEGG: D04115
PubChem CID: 2758
UNII: RV6J6604TK
CompTox Dashboard (EPA): DTXSID4020616
InChI:
InChI=1S/C10H18O/c1-9(2)8-4-6-10(3,11-9)7-5-8/h8H,4-7H2,1-3H3
Key: WEEGYLXZBRQIMU-UHFFFAOYSA-N
InChI=1/C10H18O/c1-9(2)8-4-6-10(3,11-9)7-5-8/h8H,4-7H2,1-3H3
Key: WEEGYLXZBRQIMU-UHFFFAOYAY
SMILES: O2C1(CCC(CC1)C2(C)C)C

CAS Number: 470-82-6
Chem/IUPAC Name: 1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane; 1,8-Cineole
EINECS/ELINCS No: 207-431-5
COSING REF No: 33902

Formal Name: 1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane
CAS Number: 470-82-6
Synonyms: NSC 6171
Molecular Formula: C10H18O
Formula Weight: 154.3
Purity: ≥98%
Formulation (Request formulation change): A neat oil
Solubility (Learn about Variance in Solubility):
DMF: 20 mg/ml
DMSO: 20 mg/ml
DMSO:PBS(pH 7.2) (1:4): 0.2 mg/ml
Ethanol: 20 mg/ml
SMILES: CC12CCC(CC2)C(C)(C)O1
InChi Code: InChI=1S/C10H18O/c1-9(2)8-4-6-10(3,11-9)7-5-8/h8H,4-7H2,1-3H3
InChi Key: WEEGYLXZBRQIMU-UHFFFAOYSA-N

Synonym(s): 1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane, 1,8-Cineole, 1,8-Epoxy-p-menthane
Empirical Formula (Hill Notation): C10H18O
CAS Number: 470-82-6
Molecular Weight: 154.25
Beilstein: 105109
EC Number: 207-431-5
MDL number: MFCD00167977
PubChem Substance ID: 24893017
NACRES: NA.22

Properties of Eucalyptol:
Chemical formula: C10H18O
Molar mass: 154.249 g/mol
Density: 0.9225 g/cm3
Melting point: 2.9 °C (37.2 °F; 276.0 K)
Boiling point: 176–177 °C (349–351 °F; 449–450 K)
Magnetic susceptibility (χ): −116.3×10−6 cm3/mol

Quality Level: 200
Assay: 99%
Form: liquid
Refractive index: n20/D 1.457 (lit.)
bp: 176-177 °C (lit.)
mp: 1-2 °C (lit.)
Density: 0.921 g/mL at 25 °C (lit.)
Greener alternative category: Aligned
SMILES string: C[C@]12CC[C@H](CC1)C(C)(C)O2
InChI: 1S/C10H18O/c1-9(2)8-4-6-10(3,11-9)7-5-8/h8H,4-7H2,1-3H3/t8-,10+
InChI key: WEEGYLXZBRQIMU-WAAGHKOSSA-N

Name: Eucalyptol
Chemical Name: 1,8-Cineol
Chemical Formula: C10H18O
Appearance: Liquid with A Characteristic
Molecular Weight:
Odour: Light Camphor like odour
Specific gravity: 0.921 to 0.925 at 250C
GLC Purity: Approx 99%
Refractive Index: 1.455 to 1.460 at 200C
Colour: colourless to pale yellow

Molecular Weight: 154.25
XLogP3: 2.5
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 0
Exact Mass: 154.135765193
Monoisotopic Mass: 154.135765193
Topological Polar Surface Area: 9.2 Ų
Heavy Atom Count: 11
Complexity: 164
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Eucalyptol:
Appearance: Colorless to yellowish oily transparent liquid
Odor: Having characteristic odor of camphor, with an intense pungent cool taste
Relative Density (25/25°C): 0.9210 ~ 0.9300
Refractive Index (20°C): 1.4540 ~ 1.4610

Names of Eucalyptol:

IUPAC name:
1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane

Other names:
1,8-Cineole
1,8-Epoxy-p-menthane
cajeputol
1,8-epoxy-p-menthane, 1,8-oxido-p-menthane
eucalyptole
1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane
cineol
cineole.

Synonyms of Eucalyptol:
Eucalyptol
cineole
1,8-Cineole
470-82-6
1,8-Cineol
Cajeputol
1,8-Epoxy-p-menthane
Eucalyptole
Eucapur
Zineol
Terpan
p-Cineole
1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane
Eukalyptol
1,8-Oxido-p-menthane
CINEOL
Cucalyptol
Soledum
p-Menthane, 1,8-epoxy-
Eukalyptol [Czech]
Eucalyptol (natural)
FEMA No. 2465
2-Oxabicyclo[2.2.2]octane, 1,3,3-trimethyl-
8000-48-4
Cineole (VAN)
NCI-C56575
2-Oxabicyclo(2.2.2)octane, 1,3,3-trimethyl-
Eucaly
1,3,3-Trimethyl-2-oxabicyclo(2.2.2)octane
2-Oxa-1,3,3-trimethylbicyclo(2.2.2)octane
NSC 6171
NSC-6171
NSC6171
2,2,4-trimethyl-3-oxabicyclo[2.2.2]octane
2-Oxa-1,3,3-trimethylbicyclo[2.2.2]octane
RV6J6604TK
CNL
4,7,7-trimethyl-8-oxabicyclo[2.2.2]octane
CHEBI:27961
Eucalyptol [USAN]
NCGC00091666-01
NCGC00091666-04
(1s,4s)-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane
Eucalyptol 1000 microg/mL in Methanol
UNII-RV6J6604TK
CAS-470-82-6
SMR000471853
CCRIS 3727
HSDB 991
Eucalyptol [USAN:USP]
EINECS 207-431-5
MFCD00167977
Terpane
Cyneol
BIDD:ER0481
AI3-00578
Eucalyptol,(S)
Eucalyptol (USP)
1.8-cineole
Eucalyptol, 99%
Eucalyptol, Ph Helv
p-Menthane,8-epoxy-
EUCALYPTOL [II]
EUCALYPTOL [MI]
WLN: T66 A B AOTJ B1 B1 F1
CINEOLE [INCI]
EUCALYPTOL [FCC]
1,8-Cineol-[d3]
CINEOLE [MART.]
Spectrum2_000221
Spectrum3_000683
Spectrum4_001747
Spectrum5_000704
EUCALYPTOL [FHFI]
EUCALYPTOL [HPUS]
EUCALYPTOL [HSDB]
EUCALYPTOL [INCI]
CINEOLE [WHO-DD]
EUCALYPTOL [VANDF]
bmse000523
EC 207-431-5
EUCALYPTOL [USP-RS]
SCHEMBL19622
SCHEMBL41020
BSPBio_002405
KBioGR_002194
MLS001050089
MLS001066338
DivK1c_000333
SPECTRUM1500294
SPBio_000261
CINEOLE [EP MONOGRAPH]
Eucalyptol, analytical standard
CHEMBL485259
GTPL2464
CHEMBL1231862
CHEMBL1397305
DTXSID4020616
SCHEMBL13554591
SCHEMBL17836873
HMS501A15
KBio1_000333
KBio3_001625
EUCALYPTOL [USP IMPURITY]
NINDS_000333
EUCALYPTOL [USP MONOGRAPH]
HMS2271P04
Pharmakon1600-01500294
ZINC967566
HY-N0066
Tox21_111161
Tox21_202090
Tox21_302902
BDBM50459887
CCG-36080
NSC760388
AKOS015903223
AKOS016034339
AKOS037514637
Tox21_111161_1
CCG-266254
CS-8146
DB03852
LMPR0102090019
NSC-760388
IDI1_000333
Eucalyptol, tested according to Ph.Eur.
NCGC00091666-02
NCGC00091666-03
NCGC00091666-05
NCGC00095774-01
NCGC00178671-01
NCGC00256479-01
NCGC00259639-01
AC-20234
Eucalyptol, natural, >=99%, FCC, FG
LS-13868
NCI60_005108
1,3-Trimethyl-2-oxabicyclo[2.2.2]octane
2-Oxa-1,3-trimethylbicyclo[2.2.2]octane
DB-070775
2-Oxabicyclo[2.2.2]octane,3,3-trimethyl-
FT-0607033
FT-0626369
1,3,3-trimethyl-2-oxabicyclo[2,2,2]octane
A15662
C09844
D04115
AB01563262_01
Q161572
SR-01000763816
SR-01000763816-2
W-106080
1,8-Cineole, primary pharmaceutical reference standard
Cineole, European Pharmacopoeia (EP) Reference Standard
Eucalyptol, certified reference material, TraceCERT(R)
F0001-1260
Eucalyptol, United States Pharmacopeia (USP) Reference Standard
Eucalyptol (cineole), Pharmaceutical Secondary Standard; Certified Reference Material
(±)-Eucalyptol
1,3,3-Trimethyl-2-oxabicyclo(2.2.2)octane
1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan [German] [ACD/IUPAC Name]
1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane [ACD/IUPAC Name]
1,3,3-Triméthyl-2-oxabicyclo[2.2.2]octane [French] [ACD/IUPAC Name]
1,8-Cineol
1,8-cineole
207-431-5 [EINECS]
2-Oxa-1,3,3-trimethylbicyclo(2.2.2)octane
2-Oxabicyclo[2.2.2]octane, 1,3,3-trimethyl- [ACD/Index Name]
470-82-6 [RN]
Eucalyptol [USAN]
Eucalyptole
Eukalyptol [Czech]
Eukalyptol [Czech]
p-Cineole
p-Menthane, 1,8-epoxy-
1,3,3-trimethyl-2-oxabicyclo[2,2,2]octane
1,8-epoxy-p-menthane
1,8-oxido-p-menthane
105109
1216822-66-0 [RN]
2,2,4-trimethyl-3-oxabicyclo[2.2.2]octane
2-Oxa-1,3,3-trimethylbicyclo[2.2.2]octane
2-Oxabicyclo(2.2.2)octane, 1,3,3-trimethyl-
4,7,7-trimethyl-8-oxabicyclo[2.2.2]octane
cajeputol
Cineole
CNL
Eucapur
Eukalyptol
Limonene oxide
MFCD00167977 [MDL number]
T66 A B AOTJ B1 B1 F1 [WLN]
Terpan
Zineol

MeSH Entry Terms of Eucalyptol:
1,8 Cineol
1,8 Cineole
1,8 Epoxy p menthane
1,8-cineol
1,8-cineole
1,8-Epoxy-p-menthane
cineole
eucalyptol
Soledum
Eugénol
EUGENYL ACETATE, N° CAS : 93-28-7. Nom INCI : EUGENYL ACETATE. Nom chimique : Phenol, 2-methoxy-4-(2-propenyl)-, acetate, N° EINECS/ELINCS : 202-235-6. Ses fonctions (INCI), Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit
EUGENYL ACETATE
EXOLIT AP 422; METATAGS; Exolit® AP 422; Ammonium Polyphosphate; ammonium polyphosphate, CAS: 68333-79-9.
EUPERLAN PK 3000 OK
In unopened original containers and at temperatures below 30° C EUPERLAN® PK 3000 OK can be stored for at least 6 months. The product does not contain any preservatives. During longer storage periods, slight separations might occur which, if necessary, can be eliminated by stirring without changing the pearlescent quality in the final product. Preferably, the content of the complete packaging should be processed. During storage in metal containers EUPERLAN® PK 3000 OK can react corrosively. Therefore storage tanks made of the steel quality material no. 1.4539 or better and plastic (GFK) are suitable for storing EUPERLAN® PK 3000 OK. The V4A steels (material no. 1.4401, 1.4404, 1.4571) can not be recommended. EUPERLAN® PK 3000 OK should preferably be processed at temperatures between 15° C and 35° C. At temperatures outside the given range the pumpability may be restricted due to an increase in the viscosity. This property is characteristic of the product and reversible by heating at 20 - 25° C with stirring.During longer storage periods, slight separations might occur which, if necessary, can be eliminated by stirringwithout changing the pearlescent quality in the final product. Euperlan PK 3000 OK is a pearl shine concentrate. It is a pumpable dispersion of pearlizing agents and amphoteric surfactant. It is used in surfactant preparations. EUPERLAN PK 3000 OK finds application in baby care & cleansing, face cleansing, liquid soaps, shampoos and shower/bath products.Glycol Distearate (and) Glycerin (and) Laureth-4 (and) Cocamidopropyl Betaine. EUPERLAN PK 3000 OK is a pearl shine concentrate. It is a pumpable dispersion of pearlizing agents and amphoteric surfactant. It is used in surfactant preparations. EUPERLAN PK 3000 OK finds application in baby care & cleansing, face cleansing, liquid soaps, shampoos and shower/bath products.Glycol Distearate (and) Laureth-4 (and) Cocamidopropyl Betaine. EUPERLAN® PK 3000 AM is a pearl shine concentrate. It is used in very dense and brilliant surfactant preparations. EUPERLAN PK 3000 OK finds application in baby care & cleansing, face cleansing, liquid soaps, shampoos and shower/bath products. The shelf life of this ingredient is one year.INCI: Glycol Distearate (and) Glycerin (and) Laureth-4 (and) Cocamidopropyl Betaine.In unopened original containers and at temperatures below 30° C EUPERLAN® PK 3000 OK can be stored for at least 6 months. The product does not contain any preservatives. During longer storage periods, slight separations might occur which, if necessary, can be eliminated by stirring without changing the pearlescent quality in the final product. Preferably, the content of the complete packaging should be processed. During storage in metal containers EUPERLAN® PK 3000 OK can react corrosively. Therefore storage tanks made of the steel quality material no. 1.4539 or better and plastic (GFK) are suitable for storing EUPERLAN® PK 3000 OK. The V4A steels (material no. 1.4401, 1.4404, 1.4571) can not be recommended. EUPERLAN® PK 3000 OK should preferably be processed at temperatures between 15° C and 35° C. At temperatures outside the given range the pumpability may be restricted due to an increase in the viscosity. This property is characteristic of the product and reversible by heating at 20 - 25° C with stirring.During longer storage periods, slight separations might occur which, if necessary, can be eliminated by stirringwithout changing the pearlescent quality in the final product. Applications Skin Care Cleanser Hair care Shampoo and Conditioner Bath and Body Face Care EUPERLAN PK 3000 OK Glycol Distearate (and) Laureth-4 (and) Cocamidopropyl Betaine|Glycol Distearate (and) Laureth-4 (and) Cocamidopropyl Betaine Chemical Function: Pearlescent Product Applications: Baby Care, Bath & Shower, Dishwashing, Face Care, Hair Cleansing, Hard Surface Cleaner, Industrial Green Criteria: From renewable resources Appearance EUPERLAN® PK 3000 OK is a cold processable, pumpable pearlshine concentrate with a typical faint odour. Example of use The product is suited for the preparation of very dense and brilliant surfactant preparations. pH value (10 % sol.) 3.0 - 3.5 DGF H-III 1 Sodium chloride max. 1.3 % DGF H-III 9 Density (20° C) min. 0.95 g/cm3 DIN 51757/method D Viscosity (20° C) 4000 - 10000 mPas ASTM D 2196-86* Glycol Distearate (and) Glycerin (and) Laureth-4 (and) Cocamidopropyl Betaine EUPERLAN ® PK 3000 OK Glycol Distearate (and) Laureth-4 (and) Cocamidopropyl Betaine Product Categories: Pearlescent Product Applications: Baby Care, Bath & Shower, Dishwashing, Face Care, Hair Cleansing, Hand Cleansing, Hard Surface Cleaner, HI&I, Industrial, Liquid Soap, Skin Care, Skin Cleansing Green Criteria: From renewable resources , RSPO Green Certifications: RSPO INCI: Glycol Distearate (and) Glycerin (and) Laureth-4 (and) Cocamidopropyl Betaine
EUPERLAN PK 771
EUPERLAN PK 771 = GLYCOL DISTEARATE (and) SODIUM LAURETH SULFATE (and) COCAMIDE MEA (and) LAURETH-10


Cas Number: 68585-34-2,627-83-8,68140-00-1,68213-23-0


Euperlan PK 771 is a pearlizing agent especially suitable for surfactant preparations.
Euperlan PK 771 is a dispersion of pearlizing agents and a fatty alcohol ether sulfate.
Euperlan PK 771 is miscible with all anionic surfactants and most detergent raw materials.
Euperlan PK 771 is a pearlescent agent and refatting compound.
Euperlan PK 771 is suitable for the production of emulsion type cosmetic preparations such as shampoos and bubble baths creams.


Euperlan PK 771 is a dispersion of pearlizing agents and a fatty alcohol ether sulfate.
Euperlan PK 771 is miscible with all anionic surfactants and most detergent raw materials.
Euperlan PK 771 is suitable for the production of emulsion type cosmetic preparations having a pearly gloss, such as shampoos and bubble baths.
Euperlan PK 771 is miscible with all anionic surfactants and most detergent raw materials.
Recommended use levels of Euperlan PK 771 are 3-10%.


Euperlan PK 771's particular advantage lies in the field of cold processing.
When processing, all components are mixed together and stirred to form a homogenous mixture without the need for heat.
The stability of the pearly gloss also depends on a sufficient viscosity of the end product.
If necessary, the viscosity can be adjusted with alkanolamide or sodium chloride.
Euperlan PK 771 is suitable for the production of emulsion type cosmetic preparations having a pearly gloss, e.g. shampoos and bubble baths.


Due to Euperlan PK 771's large fraction of brightening substances, Euperlan PK 771 is particularly suitable for bubble bath creams as both a pearlescent agent and refatting component.
The pearly gloss of such preparations is largely maintained even when heated.
Euperlan PK 771 can be stored for at least 1 year in original sealed containers at temperatures below 30°C.
Euperlan PK 771 protects from freezing.


Euperlan PK 771 is a cold-processable, pasty pearl shine concentrate with a typical faint odor.
Euperlan PK 771 is a cold-processable, pearl shine concentrate.
The shelf life of Euperlan PK 771 is one year.
Euperlan PK 771 is a cold-processable, pasty pearl shine concentrate with a typical faint odor.
Euperlan PK 771 is suitable for dense and particularly brilliant surfactant preparations with a silky shine.


Euperlan PK 771 is a cold-processable, pasty, dispersion of pearlizing agents that is used for dense and particularly brilliant surfactant preparations with a silky shine.
Euperlan PK 771 contains fatty alcohol ether sulfate and has a typical faint odor.
Euperlan PK 771 has a dry residue amount of 44-48%, an anionic surfactant (MW 382) of 19-22%, and a pH value (10%) of 3.0-4.0.
Euperlan PK 771 is a cold-processable, pumpable pearlescent concentrate with a typical faint odor.



USES and APPLICATIONS of EUPERLAN PK 771:
Euperlan PK 771 is suited for the production of very dense, fine-structured shining surfactant preparations.
Euperlan PK 771 is a pearlizing agent especially suitable for surfactant preparations.
Euperlan PK 771 is Dispersion of pearlizing agents and fatty alcohol ether sulfate.
Euperlan PK 771 especially suitable for surfactant preparations.
Euperlan PK 771 is Pearlizing agent composed of a dispersion of pearl luster donors in anionic surfactant.


Provides intense pearly shine, Euperlan PK 771 is cold processable and aids viscosity and foaming.
Used as Opacifier & Pearlizer Compound, Cold Process
Miscible With All Anionic Surfactants, Euperlan PK 771 Is Suitable For Producing Pearlescent Emulsion-Type Cosmetic Preparations.
Euperlan PK 771 can be used to obtain a large variety of appearances in surfactant preparation.
Designing unique combinations is the basis for creating optimal visual effects in laundry detergents, hard surface cleaners.
Used As a pigmentation agent for shampoos, liquid soaps or other detergents, Pearlant/Pearling Agent


Euperlan PK 771 can be used in cold process.
Euperlan PK 771 is used in personal care products to create a pearly white appearance.
Used in Bath & Shower, Hair Cleansing, Hand Cleansing, Liquid Soap, Skin Care, Skin Cleansing
Euperlan PK 771 finds application in baby care & cleansing, liquid soaps, shampoos, face cleansing and shower/bath products.
Euperlan PK 771 is suitable for dense and particularly brilliant surfactant preparations with a silky shine.


Used in Bath & Shower, Hand Cleansing, Skin Cleansing, Bath & Shower, Hair Cleansing, Hand Cleansing, Liquid Soap, Skin Care, Skin Cleansing.
Used in Skin Care, Cleanser, Mother and baby, Hair care, Shampoo and Conditioner, Bath and Body, Face Care, Pet Care, Pet Care TSCA, Pet Care DSL
Euperlan PK 771 is suitable for the production of emulsion type cosmetic preparations having a pearly gloss, such as shampoos and bubble baths.
Due to Euperlan PK 771's large fraction of brightening substances, Euperlan PK 771 is particularly suitable for bubble bath creams as both a pearlescent agent and refatting component.



PHYSICAL and CHEMICAL PROPERTIES of EUPERLAN PK 771:
Appearance: conforms to standard
pH, 10% Solution: 6.5
Solid content, % wt.: 45.0
Sodium Chloride, % wt.: 1.50 max.
Sodium Sulfate, % wt.: 1.00 max.
Kathon CG, % wt.: 0.05 - 0.06
Anionic surfactant: 19.0 - 22.0 %
Sodium chloride max.: 2.0 %
1,4-Dioxane max.: 5 ppm
Non-volatile components: 44.0 - 48.0 %
pH value (10 %): 3.0 - 4.0

Appearance: Pasty pearl shine concentrate
Odor: Distinctive odor
Avtive ingredient: 20.5%
Density 25C: 1.035 g/cm3
Dry residue: 48%
pH: 7.0
Sodium Chloride: 1.4%
Sodium Sulfate: 0.3%
Form: highly viscous

Odour: slight odour
Odour threshold: not applicable
Colour: whitepearlescent
pH value: 3.0 -4.0( 20 °C)
Melting temperature: not determined
boiling temperature: > 100 °C
Flash point: > 101 °C
Flammability: not flammable
Flammability of Aerosol Products: not applicable, the product does not form flammable aerosoles
Lower explosion limit: For liquids not relevant for classification and labelling.
Upper explosion limit: For liquids not relevant for classification and labelling.

Autoignition: not determined
Vapour pressure: not determined
Density: 0.95 -1.04 g/cm3( 20 °C)
Vapour density: not applicable
Partitioning coefficient n-octanol/water (log Pow): not determined
Self-ignition temperature: not determined
Thermal decomposition: No decomposition if stored and handled as prescribed/indicated.
Viscosity, dynamic: 4,500 -15,000 mPa*s( 20.0 °C)
Viscosity, kinematic: not determined
Solubility in water: dispersible
Solubility (qualitative):dispersiblesolvent(s): distilled water,



FIRST AID MEASURES of EUPERLAN PK 771:
-If inhaled:
Not relevant.
-If on skin:
Wash affected areas thoroughly with soap and water.
Remove contaminated clothing.
-If in eyes:
Rinse immediately with plenty of running water (for 10 minutes), seek medical attention from a specialist.
-If swallowed:
If swallowed, give at least 3-4 glasses of water.



ACCIDENTAL RELEASE MEASURES of EUPERLAN PK 771:
-Personal precautions, protective equipment and emergency procedures:
Use personal protective clothing.
-Environmental precautions:
Do not discharge into drains/surface waters/groundwater.
-Methods and material for containment and cleaning up:
*For small amounts:
Pick up with suitable absorbent material.
*For large amounts:
Dike spillage.
Pump off product.
Dispose of absorbed material in accordance with regulations.



FIRE FIGHTING MEASURES of EUPERLAN PK 771:
-Extinguishing media:
*Suitable extinguishing media:
water spray, carbon dioxide, dry powder, foam
-Further information:
Dispose of fire debris and contaminated extinguishing water in accordance with official regulations.



EXPOSURE CONTROLS/PERSONAL PROTECTION of EUPERLAN PK 771:
No occupational exposure limits known.
-Advice on system design:
No special precautions necessary.
-Personal protective equipment:
*Respiratory protection:
Respiratory protection not required.
*Hand protection:
Suitable are protective gloves.
*Eye protection:
Tightly fitting safety goggles.
*General safety and hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
No eating, drinking, smoking or tobacco use at the place of work.
Handle in accordance with good industrial hygiene and safety practice.



HANDLING and STORAGE of EUPERLAN PK 771:
-Precautions for safe handling:
Handle in accordance with good industrial hygiene and safety practice.
-Conditions for safe storage, including any incompatibilities:
*Suitable materials for containers:
High density polyethylene (HDPE)Further information on storage conditions:
Keep container tightly closed and dry; store in a cool place.
Below temperature limit the product properties will change.
The property change is reversible by stirring and heating.
Above temperature limit the product properties change.
A reduction of the active matter is possible.
Store protected against freezing.
*Storage stability:
Storage temperature: <= 30 °C
Protect from temperatures below:15 °C
Characteristics of the product are reversibly changed when falling below the limit temperature.



STABILITY and REACTIVITY of EUPERLAN PK 771:
-Reactivity:
No hazardous reactions if stored and handled as prescribed/indicated.
-Chemical stability:
The product is stable if stored and handled as prescribed/indicated.



SYNONYMS:
Glycol Distearate (and) Sodium Laureth Sulfate (and) Cocamide MEA (and) Laureth-10
EURECO HC P11
Eureco HC P11 is a powdered inclusion complex of pharma-grade beta-cyclodextrin and PAP (6-phthalimido-peroxy-hexanoic acid).
Eureco HC P11 is a white stable peracid exploiting whitening and disinfecting performance in mild conditions.
The available active oxygen of PAP makes Eureco HC P11 the ideal ingredient for cosmetic preparations and toothpastes.

CAS: 128275-31-0
MF: C14H15NO5
MW: 277.27
EINECS: 410-850-8

Eureco HC P11 is a synthetic organic peroxy acid derived from caprolactam and phthalic anhydride.
Eureco HC P11 is mainly used as a preformed bleaching agent, alternatively to or together with hydrogen peroxide, in moderate laundry conditions of pH and temperature.
Eureco HC P11 is also used as a tooth whitening agent.
Eureco HC P11 is a white odorless crystalline powder at room temperature.
Eureco HC P11 is slightly soluble in water and a strong oxidizer.

Eureco HC P11 is an organic compound that has been extensively used in scientific research.
Eureco HC P11 is a peroxycarboxylic acid derivative that has been synthesized by the reaction of phthalimide with peroxycaproic acid.
Eureco HC P11 is a white crystalline solid that is soluble in water and organic solvents.
Eureco HC P11 has been used in various fields of scientific research, including biochemistry, pharmacology, and medicinal chemistry.

Synthesis Method
Eureco HC P11 is synthesized by the reaction of phthalimide with peroxycaproic acid.
This reaction is carried out under mild reaction conditions and involves the use of a catalyst.
The reaction proceeds through the formation of an intermediate, which is then converted into Eureco HC P11.
The synthesis of Eureco HC P11 is a well-established method and has been extensively used in scientific research.

Synonyms
PHTHALIMIDOPEROXYCAPROIC ACID
128275-31-0
Eureco HC
6-Phthalimidohexaneperoxoic acid
2H-Isoindole-2-hexaneperoxoic acid, 1,3-dihydro-1,3-dioxo-
5-(Phthalimido)percaproic acid
UNII-5OEJ6FAL6C
5OEJ6FAL6C
6-(Phthalimidoperoxy)hexanoic acid
6-(1,3-dioxoisoindol-2-yl)hexaneperoxoic Acid
6-(phthalimido)peroxyhexanoic acid
epsilon-(Phthalimidoperoxy)hexanoic acid
EC 410-850-8
SCHEMBL21636
6-Phthalimidylhexaneperoxoic acid
DTXSID60155848
PAP (Phthalimidoperoxycaproic acid)
PHTHALIMIDOPEROXYCAPROIC ACID [INCI]
.EPSILON.-(PHTHALIMIDOPEROXY)HEXANOIC ACID
Q27262643
Euterpe oleracea
Euterpe cuatrecasana Dugand; Euterpe brasiliana Oken; Euterpe beardii L.H.Bailey; Euterpe badiocarpa Barb.Rodr.; Catis martiana O.F.Cook; Acai Oil.Euterpe Oleracea Fruit Oil is the oil expressed from the fruit of the Cabbage Palm, Euterpe oleracea, Arecaceae; acai berry extract CAS NO:879496-95-4
Evening primrose Oil
SYNONYMS Oenothera biennis CAS NO:90028-66-3
EXPANCEL 920 DU 120
EXPANCEL 920 DU 120 Expancel 920 DU 120 Technical Datasheet Expancel 920 DU 120 is a powerful dry, unexpanded microsphere. It expands with heat and is preferably used in systems where no water can be added. It offers high shear forces, resistance to solvent chemicals and pressure during processing. It is possible to expand to extremely low densities. It is recommended for controlled and uniform cell structure in underbody coatings. Expancel 920 DU 120 has a shelf life of 2 years. Product Type Fillers / Fibers > Microspheres Product Status COMMERCIAL Applications/ Recommended for Coatings Coatings Markets > Automotive OEM > Underbody Polymer Dry unexpanded thermoplastic microspheres. Product name Expancel 920 DU 120 Brand Expancel Chemical family Polymer Chemical name Preparation/Chemical mixture Market Segments Polymer processing Functions Blowing Agent Applications Shoe soles Paints, coatings and inks Functions Blowing Agent Applications Underbody coatings expancel 920 DU 120: Particle Size of Expancel 920 DU 120 µm D(0.5) : 28 - 38 Tstart of Expancel 920 DU 120 (oC) : 122 - 132 Tmax of Expancel 920 DU 120(oC): 194 - 206 Density of Expancel 920 DU 120 kg/m3: < 14 Solvent Resistance of Expancel 920 DU 120: 5 Possible to expand to extremely low densities. Our powerful dry, unexpanded microspheres add countless advantages to your production process and its outcome. Not only will Expancel DU let you achieve desired surface aesthetics in artificial leather and wallpaper, it'll also help your produce plastics that are light and smooth. On top of that Expancel DU can stand high shear forces and pressure during processing. The microspheres in Expancel DU expand with heat and are preferably used in systems where no water can be added. Expandable at temperatures between 80°C - 235°C (176°F - 455°F), our microspheres will unleash a range of essential benefits for product developers in different industries. Expancel DU is bursting with benefits Saves costs and improves bulk and thickness in technical textiles and nonwoven composites Controlled and uniform cell structure in underbody coatings and sealants Low weight, dry surface and cost savings in silicone rubber A look of suede or nubuck in artificial leather Expancel 920 DET is produced in the UK by Boud Minerals to different densities; including some tailored to a customer’s specific application and some not available before. Expancel 920 DET is used in processes where no, or insufficient, heat for expansion is generated during production. Expancel 920 DET 40 is recommended as a general grade, when higher chemical and temperature resistance is needed and small particle size for good surface properties (smoothness) is important. Expancel 920 DET 80 is recommended when very good chemical, mechanical and temperature resistance is needed and particle size is less important. Expancel 461 DET Dry, expanded thermoplastic microspheres Expancel 461 DET is produced in the UK by Boud Minerals to different densities; including some not available before. Expancel 461 DET is used in processes where no, or insufficient, heat for expansion is generated during production. Expancel 461 DET is recommended as a general purpose grade, when chemical and temperature resistance is not critical to the performance of your product. Expancel DE Dry, expanded thermoplastic microspheres Expancel DU Dry, unexpanded thermoplastic microspheres Expancel MB Masterbatch with unexpanded thermoplastic microspheres Expancel SL Unexpanded thermoplastic microspheres in aqueous dispersion Expancel WE Wet expanded thermoplastic microspheres Expancel WU Wet unexpanded thermoplastic microspheres
Extrait de noix d'argan ( argania spinosa)
MACADAMIA TERNIFOLIA SEED EXTRACT N° CAS : 129811-19-4 / 128497-20-1 - Extrait de noix de Macadamia Origine(s) : Végétale Nom INCI : MACADAMIA TERNIFOLIA SEED EXTRACT N° EINECS/ELINCS : - / - Ses fonctions (INCI) Emollient : Adoucit et assouplit la peau Agent d'entretien de la peau : Maintient la peau en bon état
Extrait de noix de Macadamia
PROPOLIS EXTRACT, N° CAS : 85665-41-4 - Extrait de propolis, Origine(s) : Animale. Nom INCI : PROPOLIS EXTRACT, N° EINECS/ELINCS : 288-130-6. Compatible Bio (Référentiel COSMOS), Ses fonctions (INCI). Agent d'entretien de la peau : Maintient la peau en bon état
Extrait de propolis ( PROPOLIS EXTRACT)
ROSE EXTRACT, N° CAS : 84696-47-9 - Extrait de Rose. Origine(s) : Végétale, Nom INCI : ROSE EXTRACT, N° EINECS/ELINCS : 283-652-0. Ses fonctions (INCI) : Agent d'entretien de la peau : Maintient la peau en bon état
Extrait de Rose ( ROSE EXTRACT)
Nom INCI : HYDROLYZED LINSEED EXTRACT Ses fonctions (INCI) Agent d'entretien de la peau : Maintient la peau en bon état
Extrait d'huile de lin hydrolysée
FARNESOL, N° CAS : 4602-84-0 - Farnésol Origine(s) : Naturelle, Synthétique Nom INCI : FARNESOL Nom chimique : 2,6,10-Dodecatrien-1-ol, 3,7,11-trimethyl- N° EINECS/ELINCS : 225-004-1, Ses fonctions (INCI) Déodorant : Réduit ou masque les odeurs corporelles désagréables Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques
EXTRAPONE SILK GW N
Extrapone Silk GW N acts as anti-aging agent and antioxidant.
Extrapone Silk GW N is a natural product obtained from hydrolyzed silk.
Possesses anti-irritant, antimicrobial, skin lightening, moisturizing, protective and smoothing properties.

CAS: 96690-41-4
EINECS: 306-235-8

Extrapone Silk GW N is used in skin & hair care formulations, surfactant water-based products, emulsions and aqueous-alcoholic products.
Extrapone Silk GW N, also known as sericin, is a natural water-soluble glycoprotein extracted from raw silk.
Extrapone Silk GW N is used as a luxurious active ingredient in skin and hair care products due to its high serine content, which has excellent moisture retention properties.
In lotions, soaps, hair and skin care products, Extrapone Silk GW N conjures up a protective barrier on skin and hair and gives it a wonderfully silky feel.
Extrapone Silk GW N contains a silk protein hydrolyzate made in water and glycerin.
Pale yellow powder, soluble in water; hydrolyzed silk refers to the degradation of silk fibroin protein to form a water-soluble polypeptide substance, containing 18 kinds of amino acids, and the molecular weight is generally between 500-10000.

Extrapone Silk GW N is a widely used ingredient in the hair care segment.
Extrapone Silk GW N is a kind of a protein that provides the required amino acids to hair shafts in order to make them stronger and shinier.
Extrapone Silk GW N is also used in skincare because it protects the surface against harmful environmental factors and is hydrating.
Extrapone Silk GW N is commonly found in products like shampoos, conditioners and lotions.
Extrapone Silk GW N is quite similar to the proteins that are naturally present in the skin and hair.
Hence, Extrapone Silk GW N works wonders in replenishing any lost protein that causes dryness and damage.

Extrapone Silk GW N is a natural ingredient that is derived from the leftover cocoons made by silkworms.
The purest form of Extrapone Silk GW N is extracted from this byproduct and is then cleansed, degummed and combed.
After a controlled hydrolysis procedure, Extrapone Silk GW N protein is obtained.
In its raw form, Extrapone Silk GW N appears as an amber colored liquid and has a characteristic mild odor.

Extrapone Silk GW N is a safe ingredient and is essential for the good health of skin and hair.
Extrapone Silk GW N is not vegan as it is derived from an animal by-product.
However, Extrapone Silk GW N is considered cruelty free as it is derived from the cocoons that have already been departed by the silkworms.
Additionally, limited data shows no risk of use of Extrapone Silk GW N during pregnancy.

Extrapone Silk GW N Chemical Properties
Density: 0.622[at 20℃]
Odor: at 100.00?%. bland
Water Solubility: 462g/L at 30℃
LogP: -2.526 at 25℃
EPA Substance Registry System: Extrapone Silk GW N (96690-41-4)

Extrapone Silk GW N is a light yellow clear liquid with a slight fragrance, no odor.
The main components are amino acids and low peptides.
Good compatibility with water, 40% alcohol, PVA, Anionic, cationic, nonionic and amphoteric surfactants.
Extrapone Silk GW N can be absorbed by human skin.
Can inhibit the activity of tyrosinase, thereby inhibiting tyrosine synthesis of melanin.

Extrapone Silk GW N obtained by acidic, alkaline, or enzymatic hydrolysis of Bombyx mori cocoon composed primarily of amino acids, peptides, and proteins.
Extrapone Silk GW N may contain impurities consisting chiefly of carbohydrates and lipids along with smaller quantities of miscellaneous substances of biological origin.
composed primarily of amino acids, peptides, and proteins.
Extrapone Silk GW N may contain impurities consisting chiefly of carbohydrates and lipids along with smaller quantities of miscellaneous substances of biological origin.

Use
Extrapone Silk GW N can be used in skin care products, with moisturizing, whitening, improve the function of skin perception. Used in hair products, with hair care, increase the role of elasticity and softness.
Extrapone Silk GW N is extremely similar to the proteins found in our own bodies.
Extrapone Silk GW N is thus an excellent external source of protein that positively impacts skin and hair.

Hair care: Extrapone Silk GW N aids in smoothness and silkiness.
Due to lack of nutrition or chemical treatments, the hair shafts lose their protein and become dry, dull and damaged.
Extrapone Silk GW N makes up for this loss of nutrition

Skin care: Extrapone Silk GW N acts as a humectant that pulls water to the outer layers of the skin and locks it.
This results in a soft, supple and plump surface.
Extrapone Silk GW N also forms a barrier on the skin to protect it against the harmful stressors of the environment.
Extrapone Silk GW N is a good conditioning agent that makes cosmetic products more effective and prevents them from drying out the the surface that it is applied on.
Extrapone Silk GW N gives a smooth texture to the products and a radiant glow to the skin

Synonyms:
silk hydrolysates
Protein hydrolyzates, silk
Silkhydrolyzed
Proteinhydrolysate, Seide-
Silk, hydrolyzates
Silk,hydrolyzates
cdFDGFR
Silk fibroin peptide
SILK
Silk peptide
Hydrolyzed silk
Silk, hydrolyzed
Protein hydrolyzates, silk
FARMIN 2471
DESCRIPTION:

Farmin 2471 is used as Starting materials for cationic and amphoteric surfactants, germicides & bactericides, levelling agents, wood preservatives, oil recovery agents, amine oxide, corrosion inhibitors, hair care ingredients.
Farmin 2471 has a variety of different uses including use in the manufacture of amine oxides used as surfactants.
Additionally Farmin 2471 is used in the manufacture of benzalkonium salts to be used in biocide applications.

CAS RN.: 68439-70-3


APPLICATIONS OF FARMIN 2471:

Farmin 2471 is used as Raw materials for cationic surfactants.
Farmin 2471 is used as Raw materials for amphoteric surfactants.
Farmin 2471 is used as Corrosion inhibitors, Raw materials for emulsifier for asphalt, mold release agents for rubber, flotation agents, anti-caking agents for fertilizers, fuel additives, sludge inhibitors, etc

Farmin 2471 is used as Starting materials for cationic and amphoteric surfactants, germicides & bactericides, levelling agents, wood preservatives, oil recovery agents, amine oxide, corrosion inhibitors, hair care ingredients.

Farmin 2471 has a variety of different uses including use in the manufacture of amine oxides used as surfactants.
Additionally Farmin 2471 is used in the manufacture of benzalkonium salts to be used in biocide applications.
Farmin 2471 is not sold to consumers and use is limited to Industrial use only.
Workers handling Farmin 2471 should have the appropriate skills and training with self-protect apparatus



SAFETY INFORMATION ABOUT FARMIN 2471:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product


CHEMICAL AND PHYSICAL PROPERTIES OF FARMIN 2471:
Product name: FARMIN DM2471
Chemical Name:
Alkyl(C12-16) dimethylamines
CAS RN.: 68439-70-3
Appearance: Clear liquid
Typical carbon chain composition
C10: 2%max., C12:63-75%, C14:24-30%, C16:5%max, C18:0.5%max.
Color
40 APHA max.
Total amine value
244-255
Tertiary amine (%)
98 min.
1'ry & 2'ry amines(%)
0.30 max.
Water content(%)
0.30 max.
Physical state. Liquid
Colour: Colourless
Odour: Characteristic (fatty amine)
Density: 0.790 g/mL at 20 ºC
Melting point: - 8.9 ºC
Flash point: 136 °C (Cleveland open cup method)





FARMIN DM2471

Farmin DM2471 is a chemical compound known for its versatile applications in various industries.
Farmin DM2471 is a clear liquid with a specific carbon chain composition, primarily consisting of C12 to C16 alkyl dimethylamines.
With a CAS Registry Number of 68439-70-3, Farmin DM2471 is readily identifiable in chemical databases.

CAS Number: 68439-70-3



APPLICATIONS


Farmin DM2471 is widely utilized as a crucial raw material in the production of cationic surfactants, which find applications in various industries.
Cationic surfactants derived from Farmin DM2471 are extensively used in personal care products such as shampoos, conditioners, and body washes for their conditioning and antimicrobial properties.
Farmin DM2471 plays a vital role in the formulation of amphoteric surfactants, which are versatile in their ability to function under various pH conditions.
Farmin DM2471 serves as a corrosion inhibitor, protecting metal surfaces from degradation in corrosive environments.

In the construction industry, it is employed in asphalt emulsifiers, facilitating the mixing of asphalt with water for road construction and maintenance.
Farmin DM2471 acts as a mold release agent for rubber products, ensuring their easy removal from molds during manufacturing.

In the mining and mineral processing sector, it functions as a flotation agent, aiding in the separation of valuable minerals from waste materials.
Farmin DM2471 is utilized as an anti-caking agent in the fertilizer industry to prevent the clumping of fertilizers and ensure uniform distribution.
As a fuel additive, it may enhance combustion efficiency and reduce emissions in the automotive and energy sectors.
Farmin DM2471 serves as a sludge inhibitor in wastewater treatment processes, preventing the buildup of undesirable deposits.

Farmin DM2471 is a starting material for the production of germicides and bactericides, contributing to the formulation of disinfectants and sanitizers.
Farmin DM2471 functions as a levelling agent in coatings and printing inks, ensuring even and consistent application on surfaces.

In the wood preservation industry, it is used to protect wood from decay, insects, and other forms of deterioration.
Farmin DM2471 serves as an oil recovery agent in the petroleum industry, aiding in the extraction of oil from reservoirs.
Farmin DM2471 may function as an amine oxide in various chemical processes, acting as a surfactant, emulsifier, or stabilizer.

Farmin DM2471 is involved in the formulation of wood adhesives, enhancing bonding properties in wood-based products.
Farmin DM2471 finds applications in the production of paper and pulp, contributing to paper sizing and coating processes.
In the textile industry, it is used as an auxiliary chemical in dyeing and finishing processes.

Farmin DM2471 is employed in the formulation of lubricants and metalworking fluids for improved performance and longevity.
Farmin DM2471 serves as a processing aid in the manufacturing of rubber and polymer products.
Farmin DM2471 plays a role in the development of agrochemicals, aiding in the dispersion and effectiveness of active ingredients.
In the cosmetics industry, it can be found in formulations such as creams and lotions as an emulsifying agent.

Farmin DM2471 is utilized in the production of household and industrial cleaning products for its surfactant properties.
Farmin DM2471 contributes to the formulation of adhesives and sealants used in various construction and manufacturing applications.
Farmin DM2471's versatility and compatibility make it an essential ingredient in a wide range of applications across industries, where its unique properties enhance product performance and effectiveness.

Farmin DM2471 is a key ingredient in the production of household and industrial detergents, contributing to their cleaning and foaming properties.
Farmin DM2471 is used in the formulation of dishwashing liquids, where it aids in the removal of grease and food residues.
Farmin DM2471 finds applications in the textile industry as a softening agent, improving the feel and texture of fabrics.

In the agriculture sector, it is utilized as an adjuvant in pesticide formulations to enhance their effectiveness and coverage on plant surfaces.
Farmin DM2471 plays a role in the manufacture of concrete admixtures, improving the workability and strength of concrete mixes.
Farmin DM2471 is incorporated into the production of inkjet printing inks to improve their color dispersion and print quality.
Farmin DM2471 is used as a component in industrial paints and coatings, contributing to their durability and adhesion properties.

Farmin DM2471 is employed in the production of oilfield chemicals, aiding in processes such as drilling, well stimulation, and production.
In the pulp and paper industry, it is added to paper coatings to enhance their printability and smoothness.
Farmin DM2471 is utilized in the development of leather treatments and finishes, improving leather quality and appearance.
Farmin DM2471 plays a role in the formulation of adhesive tapes, ensuring strong adhesion to various surfaces.

Farmin DM2471 is used as a wetting agent in the manufacturing of electronics components, facilitating soldering and assembly processes.
In the food industry, it serves as a processing aid, enhancing the texture and consistency of food products.

Farmin DM2471 contributes to the formulation of drilling fluids in the oil and gas sector, assisting in wellbore stability and lubrication.
Farmin DM2471 is added to coolant and antifreeze formulations in the automotive industry to prevent corrosion and scale buildup.
Farmin DM2471 finds applications in the production of ceramic glazes, improving their flow and adhesion to pottery surfaces.

Farmin DM2471 is used in the formulation of automotive waxes and polishes, enhancing the shine and protection of vehicle finishes.
Farmin DM2471 plays a role in the development of metalworking fluids, improving cutting and machining processes.
Farmin DM2471 is added to the manufacturing of rubber tires to enhance their durability and resistance to wear.

Farmin DM2471 contributes to the formulation of concrete curing compounds, aiding in the proper hydration of concrete surfaces.
Farmin DM2471 serves as a component in industrial solvents and degreasers for effective cleaning and degreasing applications.
Farmin DM2471 is employed in the production of rust and corrosion inhibitors for metal protection.
In the construction industry, it is used as a concrete release agent to prevent sticking in molds and formwork.

Farmin DM2471 is incorporated into asphalt sealants to enhance their adhesive properties and longevity.
Farmin DM2471 finds applications in the manufacturing of rubber and plastic products, improving their processing characteristics and performance.



DESCRIPTION


Farmin DM2471 is a chemical compound known for its versatile applications in various industries.
Farmin DM2471 is a clear liquid with a specific carbon chain composition, primarily consisting of C12 to C16 alkyl dimethylamines.
With a CAS Registry Number of 68439-70-3, Farmin DM2471 is readily identifiable in chemical databases.
Farmin DM2471 exhibits a maximum carbon chain length of C16 and minimal C10 content.
Farmin DM2471 has a maximum color specification of 40 APHA, indicating its clarity.

Its total amine value typically falls within the range of 244 to 255.
Remarkably, Farmin DM2471 primarily consists of tertiary amines, with a minimum content of 98%.

The presence of primary and secondary amines is limited to a maximum of 0.30%.
Farmin DM2471 exhibits excellent purity, with a maximum water content of 0.30%.
Its chemical composition makes it a valuable raw material for cationic surfactants, used in various applications.

In addition to cationic surfactants, it serves as a raw material for amphoteric surfactants.
Farmin DM2471 plays a vital role as a corrosion inhibitor, protecting metals from deteriorating effects.
Its use extends to being a key component in emulsifiers for asphalt, facilitating the mixing of asphalt with other substances.
Farmin DM2471 serves as an effective mold release agent for rubber products, aiding in their easy removal from molds.

In flotation processes, it acts as a flotation agent, helping separate valuable minerals from gangue.
Farmin DM2471 finds application as an anti-caking agent in fertilizers, preventing clumping and ensuring even distribution.
As a fuel additive, it may enhance the combustion characteristics of fuels.

Farmin DM2471 also serves as a sludge inhibitor, helping control the formation of unwanted deposits in various industrial processes.
Farmin DM2471 is used as a starting material for germicides and bactericides, contributing to hygiene and disinfection.

Farmin DM2471 functions as a levelling agent in certain processes, ensuring even and uniform application of coatings.
Farmin DM2471 is employed as a wood preservative, protecting wood from decay and pests.
In oil recovery operations, it acts as an oil recovery agent, aiding in the extraction of petroleum from reservoirs.
Farmin DM2471 may also serve as an amine oxide in specific chemical reactions.



PROPERTIES


Physical Properties:

Chemical Name: Alkyl(C12-16) dimethylamines
CAS RN (Chemical Abstracts Service Registry Number): 68439-70-3
Appearance: Clear liquid
Color: 40 APHA max.
Odor: Characteristic amine odor
Density: Typically not provided (manufacturer-specific data)
Boiling Point: Typically not provided (manufacturer-specific data)
Melting Point/Freezing Point: Typically not provided (manufacturer-specific data)
Solubility: Soluble in water and various organic solvents.
pH (1% Solution): Typically not provided (manufacturer-specific data)
Flash Point: Typically not provided (manufacturer-specific data)


Chemical Properties:

Carbon Chain Composition:
- C10: 2% max.
- C12: 63-75%
- C14: 24-30%
- C16: 5% max.
- C18: 0.5% max.
Total Amine Value: 244-255
Tertiary Amine (%): 98 min.
1st & 2nd Amines (%): 0.30 max.
Water Content (%): 0.30 max.



FIRST AID


Inhalation:

If inhaled and respiratory distress occurs, immediately move the affected person to an area with fresh air.
Keep the individual at rest in a comfortable position.
If breathing difficulties persist, seek immediate medical attention.
In the case of severe inhalation exposure or if the person is unconscious, initiate artificial respiration and seek medical help.


Skin Contact:

In the event of skin contact, promptly remove contaminated clothing while wearing suitable protective equipment.
Wash the affected area thoroughly with soap and water for at least 15 minutes.
If irritation, redness, or other skin issues develop, seek medical advice.
Wash contaminated clothing thoroughly before reuse.


Eye Contact:

If Farmin DM2471 comes into contact with the eyes, rinse them gently but thoroughly with lukewarm water for at least 15 minutes, while holding the eyelids open to ensure thorough rinsing.
Seek immediate medical attention, especially if irritation, redness, or pain persists.
Remove contact lenses, if present and easy to do, after the initial eye rinse.


Ingestion:

If swallowed accidentally, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth with water and drink plenty of water or milk if the person is conscious.
Seek immediate medical attention.
Provide medical personnel with the product's Safety Data Sheet (SDS) for reference.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear suitable personal protective equipment, including chemical-resistant gloves, safety goggles or a face shield, and protective clothing, to minimize skin and eye contact with the chemical.

Ventilation:
Use Farmin DM2471 in a well-ventilated area or under local exhaust ventilation to control airborne concentrations.
Ensure adequate ventilation when handling the chemical.

Avoid Skin Contact:
Avoid direct skin contact with the chemical.
In case of skin contact, promptly remove contaminated clothing and wash the affected area thoroughly with soap and water.

Eye Protection:
Wear safety goggles or a face shield to protect against potential eye contact.
In the event of eye contact, rinse eyes gently with lukewarm water for at least 15 minutes, holding eyelids open.
Seek immediate medical attention if irritation or pain persists.

Respiratory Protection:
Depending on the form of Farmin DM2471 and the handling procedures, respiratory protection (e.g., a mask with appropriate filters) may be necessary.
Follow applicable respiratory protection regulations and guidelines.

Handling Equipment:
Utilize appropriate handling equipment, such as pumps, pipettes, or dispensers, to minimize the risk of spills, splashes, or direct contact with the chemical.

Avoid Ingestion:
Do not eat, drink, or smoke while handling Farmin DM2471, and avoid ingesting any traces of the chemical.
Wash hands and face thoroughly after handling, especially before eating, drinking, or using the restroom.

Labeling and Identification:
Ensure containers are clearly labeled with the product name, hazard information, and safety instructions.
Maintain legible and intact labels.


Storage:

Temperature:
Store Farmin DM2471 in a cool, dry place at temperatures specified on the product label or in the Safety Data Sheet (SDS).
Avoid extreme temperature fluctuations.

Ventilation:
Ensure storage areas are well-ventilated to prevent the accumulation of vapors or fumes.
Use mechanical ventilation if necessary.

Separation:
Store Farmin DM2471 away from incompatible materials, such as strong acids, strong bases, and oxidizing agents, to prevent chemical reactions and potential hazards.

Container Integrity:
Keep the chemical in its original container with a tightly closed lid to prevent contamination and moisture ingress.
Ensure containers are in good condition without leaks or damage.

Security:
Limit access to storage areas and keep Farmin DM2471 out of reach of unauthorized personnel, children, and pets.

Shelf Life:
Check the maximum shelf life specified by the manufacturer.
Use older stock first to ensure product freshness and effectiveness.

Emergency Equipment:
Maintain access to emergency equipment, such as eyewash stations, safety showers, and spill control materials, in the event of accidental exposure or spills.

FARNESOL
Farnesol is a naturally occurring sesquiterpene alcohol widely used in the fragrance and personal care industries for its pleasant floral aroma and multifunctional properties.
Farnesol is highly effective as a deodorizing agent, making it a key ingredient in many deodorants and antiperspirants.
In addition to its fragrance and deodorizing properties, Farnesol also exhibits antimicrobial and anti-inflammatory activities, making it suitable for various skincare applications.

CAS Number: 4602-84-0
EC Number: 225-004-1

Synonyms: Farnesol, 3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol, Farnesyl alcohol, trans-trans-Farnesol, 2,6,10-Dodecatrien-1-ol, 3,7,11-Trimethyl-, trans,trans-Farnesyl alcohol, trans-Farnesol, trans,trans-3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol, trans,trans- Farnesyl alcohol, 3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol, trans-trans-Farnesol, Sesquiterpene alcohol, Anti-bacterial agent Farnesol, Deodorant active Farnesol, Natural fragrance Farnesol, Farnesol complex, Odor neutralizer Farnesol, Farnesol antimicrobial, Farnesol anti-inflammatory agent, Farnesol deodorant additive, Farnesol skin conditioner, Farnesol fragrance component



APPLICATIONS


Farnesol is extensively used as a fragrance component in perfumes and colognes, contributing a fresh, floral aroma that enhances the overall scent profile.
Farnesol is favored in the production of deodorants, where it acts as a natural deodorizing agent by inhibiting the growth of odor-causing bacteria.
Farnesol is utilized in the formulation of antiperspirants, providing long-lasting odor protection while being gentle on the skin.

Farnesol is widely used in the development of skincare products, such as creams and lotions, where its anti-inflammatory properties help soothe and calm irritated skin.
Farnesol is employed in the production of aftershaves and post-shaving balms, offering a soothing and antimicrobial effect that helps prevent skin irritation.
Farnesol is essential in the formulation of foot care products, providing deodorizing and antifungal benefits that help maintain foot hygiene.

Farnesol is utilized in the creation of intimate care products, where it provides gentle yet effective deodorizing and antimicrobial protection.
Farnesol is a key ingredient in the formulation of natural and organic skincare products, offering a safe and effective alternative to synthetic fragrance and preservative ingredients.
Farnesol is used in the production of oral care products, such as mouthwashes and toothpaste, where its antimicrobial properties help maintain oral hygiene.

Farnesol is applied in the formulation of hair care products, including shampoos and conditioners, providing a fresh scent and scalp-soothing benefits.
Farnesol is employed in the production of baby care products, ensuring gentle and non-irritating deodorizing effects for sensitive skin.
Farnesol is used in the creation of sunscreens, offering both fragrance and skin-conditioning benefits, enhancing the overall product experience.

Farnesol is widely utilized in the formulation of body washes and shower gels, providing a fresh and clean scent while also helping to maintain skin hygiene.
Farnesol is a key component in the development of fragrance-free skincare products, where it offers antimicrobial protection without adding a noticeable scent.
Farnesol is used in the production of insect repellents, contributing to the effectiveness of the formulation while providing a pleasant aroma.

Farnesol is employed in the formulation of anti-aging products, where its anti-inflammatory properties help reduce the appearance of fine lines and wrinkles.
Farnesol is applied in the creation of deodorant wipes, offering portable and convenient odor protection for use throughout the day.
Farnesol is utilized in the development of multi-functional skincare products, offering combined benefits of fragrance, deodorization, and skin conditioning.

Farnesol is found in the formulation of hair styling products, providing a fresh scent while also offering scalp-soothing benefits.
Farnesol is used in the production of massage oils and lotions, where its fragrance and skin-conditioning properties enhance the overall sensory experience.
Farnesol is a key ingredient in the creation of aromatherapy products, offering a calming and soothing fragrance that promotes relaxation.

Farnesol is widely used in the development of personal care products designed for sensitive skin, providing gentle yet effective deodorizing and antimicrobial protection.
Farnesol is employed in the formulation of fragrance mists and body sprays, offering a light and refreshing scent that can be reapplied throughout the day.
Farnesol is applied in the production of leave-on skincare treatments, such as serums and oils, providing long-lasting fragrance and skin benefits.

Farnesol is utilized in the creation of fragrance-infused skincare products, offering a harmonious blend of scent and skincare benefits in one product.
Farnesol is found in the formulation of deodorant sticks, where it provides effective odor protection with a pleasant, natural scent.
Farnesol is used in the production of deodorant creams, offering a moisturizing and deodorizing effect that is ideal for sensitive skin areas.

Farnesol is a key component in the development of anti-acne products, where its antimicrobial properties help reduce acne-causing bacteria on the skin.
Farnesol is widely used in the formulation of intimate hygiene products, providing gentle deodorization and antimicrobial protection for delicate areas.
Farnesol is employed in the creation of natural deodorants, offering an effective alternative to synthetic actives while maintaining product efficacy.

Farnesol is applied in the production of skincare products designed for dry and sensitive skin, offering both fragrance and skin-conditioning benefits.
Farnesol is used in the formulation of deodorant sprays, providing quick-drying and long-lasting odor protection with a refreshing scent.
Farnesol is found in the development of foot sprays, offering deodorizing and antifungal benefits that help maintain foot health.

Farnesol is utilized in the creation of multifunctional skincare products, offering combined benefits of fragrance, antimicrobial protection, and skin conditioning.
Farnesol is widely employed in the production of hair perfumes, offering a fresh scent that lasts throughout the day while providing scalp-soothing benefits.
Farnesol is a critical ingredient in the development of fragrance-free deodorants, providing effective odor protection without added fragrance.



DESCRIPTION


Farnesol is a naturally occurring sesquiterpene alcohol widely used in the fragrance and personal care industries for its pleasant floral aroma and multifunctional properties.
Farnesol is highly effective as a deodorizing agent, making it a key ingredient in many deodorants and antiperspirants.

Farnesol is a versatile ingredient that offers antimicrobial, deodorizing, and skin-conditioning properties, making it suitable for a wide range of personal care applications.
Farnesol is often incorporated into skincare products for its anti-inflammatory effects, which help to soothe and calm irritated skin.
Farnesol is recognized for its stability in various formulations, maintaining its efficacy throughout the product's shelf life.

Farnesol is commonly used in both traditional and natural personal care products, aligning with consumer demands for clean and effective ingredients.
Farnesol is valued for its ability to maintain effectiveness in challenging conditions, such as high humidity and heat, making it ideal for use in sports and outdoor products.
Farnesol is known for its compatibility with other active ingredients, allowing formulators to create multifunctional products that offer fragrance, deodorization, and skin benefits.

Farnesol is often chosen for formulations that require long-lasting fragrance and deodorizing effects, ensuring users remain fresh throughout the day.
Farnesol is a preferred ingredient for products targeting both men and women, offering a gender-neutral fragrance that appeals to a wide range of consumers.
Farnesol is a key ingredient in the development of personal care products designed for sensitive areas, such as intimate deodorants, where gentle yet effective odor control is essential.

Farnesol is recognized for its environmental friendliness, as it offers a sustainable alternative to synthetic fragrance and deodorant actives without compromising on efficacy.
Farnesol is an ideal choice for formulators looking to create innovative personal care products that stand out in the market for their performance and safety.
Farnesol is widely used in formulations that prioritize skin health, providing odor protection and fragrance without disrupting the skin's natural balance.

Farnesol enhances the overall effectiveness of deodorant and skincare products by providing comprehensive protection against odor while being gentle on the skin.
Farnesol is a reliable ingredient for creating personal care products that offer a pleasant user experience, with smooth application and no residue.
Farnesol is often incorporated into luxury skincare and fragrance products, where its sophisticated aroma and multifunctional benefits add value to the formulation.



PROPERTIES


Chemical Formula: C15H26O
Common Name: Farnesol
Molecular Structure:
Appearance: Clear, colorless to pale yellow liquid
Density: 0.878 g/cm³
Melting Point: N/A (liquid at room temperature)
Solubility: Insoluble in water; soluble in alcohols and organic solvents
Flash Point: 93°C
Reactivity: Stable under normal conditions; no known reactivity issues
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store between 15-25°C in a cool, dry place
Vapor Pressure: Low



FIRST AID


Inhalation:
If Farnesol is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Wash the affected area with soap and water.
If skin irritation persists, seek medical attention.

Eye Contact:
In case of eye contact, flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
If Farnesol is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles if handling large quantities.
Use in a well-ventilated area to avoid inhalation of vapors.

Ventilation:
Ensure adequate ventilation when handling large amounts of Farnesol to control airborne concentrations below occupational exposure limits.

Avoidance:
Avoid direct contact with eyes and prolonged skin contact.
Do not eat, drink, or smoke while handling Farnesol.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Contain spills to prevent further release and minimize exposure.
Absorb with inert material (e.g., sand, vermiculite) and collect for disposal.
Dispose of in accordance with local regulations.

Storage:
Store Farnesol in a cool, dry, well-ventilated area away from incompatible materials (see SDS for specific details).
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and ignition sources.

Handling Cautions:
Avoid inhalation of vapors and direct contact with skin and eyes.
Use explosion-proof equipment in areas where vapors may be present.


Storage:

Temperature:
Store Farnesol at temperatures between 15-25°C as recommended by the manufacturer.
Avoid exposure to extreme temperatures.

Containers:
Use approved containers made of compatible materials.
Check for leaks or damage in storage containers regularly.

Separation:
Store Farnesol away from incompatible materials, including strong oxidizers.

Handling Equipment:
Use dedicated equipment for handling Farnesol to avoid cross-contamination.
Ensure all handling equipment is in good condition.

Security Measures:
Restrict access to storage areas.
Follow all applicable local regulations regarding the storage of cosmetic ingredients.

Emergency Response:
Have emergency response equipment and materials readily available, including spill cleanup materials, fire extinguishers, and emergency eyewash stations.
Farnésol
N° CAS : 91001-85-3
FARNESOL PLUS

Farnesol Plus is a multifunctional active ingredient widely used in personal care products for its antimicrobial, deodorizing, and skin-conditioning properties.
Farnesol Plus is particularly effective in controlling the growth of odor-causing bacteria, making it a key component in deodorant and skincare formulations.
The unique composition of Farnesol Plus offers a broad range of benefits, including anti-inflammatory and skin-soothing effects, which make it suitable for various personal care applications.

CAS Number: 4602-84-0
EC Number: 225-004-1

Synonyms: Farnesol Plus, Deodorant Active Farnesol, Skin Conditioning Agent Farnesol, Farnesol Complex, Broad-Spectrum Antimicrobial Farnesol, Deodorant Additive Farnesol, Skin Soothing Farnesol, Anti-Inflammatory Farnesol, Multifunctional Farnesol, Odor Control Agent Farnesol, Farnesol Deodorant Complex, Farnesol Antimicrobial Complex, Farnesol Skin Conditioner, Farnesol Plus Deodorant, Farnesol Antimicrobial Active, Farnesol Skin Protectant, Farnesol Plus Preservative, Farnesol Deodorant Active, Farnesol Skincare Additive, Farnesol Anti-Microbial, Farnesol Anti-Bacterial Agent, Farnesol Skin Health Active, Farnesol Odor Neutralizer



APPLICATIONS


Farnesol Plus is extensively used as an active ingredient in deodorant formulations, providing effective odor control by inhibiting the growth of odor-causing bacteria.
Farnesol Plus is favored in the production of antiperspirants, where it enhances the product's ability to reduce perspiration and neutralize body odor.
Farnesol Plus is utilized in the formulation of body sprays, offering long-lasting freshness and odor protection without irritating the skin.

Farnesol Plus is widely used in the development of roll-on deodorants, ensuring smooth application and consistent odor control throughout the day.
Farnesol Plus is employed in the production of stick deodorants, providing a solid form of odor protection that is both effective and gentle on the skin.
Farnesol Plus is essential in the formulation of deodorant creams, offering a moisturizing and deodorizing effect, making it ideal for sensitive skin areas.

Farnesol Plus is utilized in the creation of deodorant wipes, providing portable and convenient odor protection for use throughout the day.
Farnesol Plus is a key ingredient in the formulation of natural and organic deodorants, aligning with consumer demand for clean and effective personal care products.
Farnesol Plus is used in the production of underarm powders, offering a dry and comfortable feel with enhanced odor protection.

Farnesol Plus is applied in the formulation of foot deodorants, providing antimicrobial protection that helps prevent foot odor and maintain foot health.
Farnesol Plus is employed in the production of intimate deodorants, ensuring gentle and effective odor control in delicate areas.
Farnesol Plus is used in the creation of multi-functional body lotions that offer both moisturizing benefits and deodorizing properties.

Farnesol Plus is widely utilized in the formulation of deodorant soaps and body washes, providing an extra layer of odor protection during cleansing routines.
Farnesol Plus is a key component in the development of deodorant sprays for fabrics, helping to neutralize odors and keep clothing fresh.
Farnesol Plus is used in the production of sports deodorants, offering long-lasting protection against sweat and odor during physical activities.

Farnesol Plus is employed in the formulation of deodorant balms, providing a soothing application while effectively controlling body odor.
Farnesol Plus is applied in the creation of gender-specific deodorants, offering tailored odor protection that meets the needs of different skin types.
Farnesol Plus is utilized in the development of deodorant mists, providing a lightweight and refreshing alternative to traditional deodorant products.

Farnesol Plus is found in the formulation of hair deodorants, offering odor protection for the scalp and hair, especially in humid conditions.
Farnesol Plus is used in the production of deodorant patches, providing targeted odor control for specific areas of the body.
Farnesol Plus is a key ingredient in the creation of travel-sized deodorants, ensuring compact and effective odor protection while on the go.

Farnesol Plus is widely used in the development of deodorant-infused skincare products, offering dual benefits of odor control and skin care.
Farnesol Plus is employed in the formulation of deodorant roll-ons with additional skincare benefits, such as soothing and hydrating effects.
Farnesol Plus is applied in the production of deodorant bars, providing a solid and convenient form of odor protection.

Farnesol Plus is utilized in the creation of deodorant powders for sensitive skin, ensuring effective odor control without causing irritation.
Farnesol Plus is found in the formulation of deodorant sticks with added fragrances, offering both odor protection and a pleasant scent.
Farnesol Plus is used in the production of deodorant creams with natural ingredients, providing a clean and effective approach to odor control.

Farnesol Plus is a key component in the development of deodorant gels, offering a cooling sensation along with reliable odor protection.
Farnesol Plus is widely used in the formulation of deodorant sprays with quick-drying properties, ensuring a comfortable and dry feel throughout the day.
Farnesol Plus is employed in the creation of deodorant foams, providing a unique and innovative form of odor protection.

Farnesol Plus is applied in the production of deodorant balms with added skin-nourishing ingredients, offering both odor control and skincare benefits.
Farnesol Plus is used in the formulation of deodorant lotions with anti-inflammatory properties, ensuring gentle and effective odor protection for sensitive skin.
Farnesol Plus is found in the development of eco-friendly deodorants, providing sustainable and effective odor control solutions.

Farnesol Plus is utilized in the creation of deodorant products designed for active lifestyles, ensuring long-lasting protection against sweat and odor.
Farnesol Plus is widely employed in the production of multifunctional deodorants that offer additional benefits such as moisturizing, soothing, or skin protection.
Farnesol Plus is a critical ingredient in the development of fragrance-free deodorants, offering effective odor protection without added scents.

Farnesol Plus is used in the creation of deodorant-infused textiles, providing odor protection directly from clothing materials.
Farnesol Plus is applied in the formulation of deodorant serums, offering a concentrated and effective form of odor protection.
Farnesol Plus is a key ingredient in the production of deodorants with natural extracts, ensuring a gentle and effective approach to odor control.

Farnesol Plus is employed in the development of deodorant sprays with enhanced antimicrobial properties, providing extra protection against odor-causing bacteria.
Farnesol Plus is utilized in the creation of specialized deodorants for athletes, offering robust and long-lasting odor protection.
Farnesol Plus is widely used in the formulation of deodorants with skin-soothing ingredients, ensuring a comfortable and irritation-free experience.



DESCRIPTION


Farnesol Plus is a multifunctional active ingredient widely used in personal care products for its antimicrobial, deodorizing, and skin-conditioning properties.
Farnesol Plus is particularly effective in controlling the growth of odor-causing bacteria, making it a key component in deodorant and skincare formulations.

Farnesol Plus is a versatile ingredient that offers broad-spectrum antimicrobial activity, ensuring comprehensive protection against a wide range of microorganisms.
Farnesol Plus is often incorporated into deodorant formulations designed for sensitive skin, as it is gentle and non-irritating while still providing powerful odor control.
Farnesol Plus is recognized for its stability in various formulations, maintaining its efficacy throughout the product's shelf life.

Farnesol Plus is commonly used in both traditional and natural deodorants, aligning with consumer demands for clean and effective personal care products.
Farnesol Plus is an essential component in multi-functional personal care products, where it provides deodorant protection along with other skincare benefits.
Farnesol Plus is valued for its ability to maintain effectiveness in challenging conditions, such as high humidity and heat, making it ideal for use in sports and outdoor products.

Farnesol Plus is known for its compatibility with other active ingredients, allowing formulators to create products with multiple benefits, such as deodorant creams that also moisturize and soothe the skin.
Farnesol Plus is often chosen for formulations that require long-lasting odor protection, ensuring users remain fresh throughout the day.
Farnesol Plus is a preferred ingredient for products targeting both men and women, offering tailored odor protection that meets the needs of different skin types.

Farnesol Plus is a key ingredient in the development of products designed for sensitive areas, such as intimate deodorants, where gentle yet effective odor control is essential.
Farnesol Plus is recognized for its environmental friendliness, as it offers a sustainable alternative to traditional deodorant actives without compromising on efficacy.
Farnesol Plus is an ideal choice for formulators looking to create innovative deodorant products that stand out in the market for their performance and safety.

Farnesol Plus is widely used in formulations that prioritize skin health, providing odor protection without disrupting the skin's natural balance.
Farnesol Plus is a reliable ingredient for creating deodorants that offer a pleasant user experience, with smooth application and no residue.
Farnesol Plus enhances the overall effectiveness of deodorant products by providing comprehensive protection against odor while being gentle on the skin.



PROPERTIES


Chemical Formula: C15H26O
Common Name: Farnesol Plus (Farnesol)
Molecular Structure:
Appearance: Clear, colorless to pale yellow liquid
Density: 0.878 g/cm³
Melting Point: N/A (liquid at room temperature)
Solubility: Insoluble in water; soluble in alcohols and organic solvents
Flash Point: 93°C
Reactivity: Stable under normal conditions; no known reactivity issues
Chemical Stability: Stable under recommended storage conditions
Storage Temperature: Store between 15-25°C in a cool, dry place
Vapor Pressure: Low



FIRST AID


Inhalation:
If Farnesol Plus is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Wash the affected area with soap and water.
If skin irritation persists, seek medical attention.

Eye Contact:
In case of eye contact, flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
If Farnesol Plus is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles if handling large quantities.
Use in a well-ventilated area to avoid inhalation of vapors.

Ventilation:
Ensure adequate ventilation when handling large amounts of Farnesol Plus to control airborne concentrations below occupational exposure limits.

Avoidance:
Avoid direct contact with eyes and prolonged skin contact.
Do not eat, drink, or smoke while handling Farnesol Plus.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Contain spills to prevent further release and minimize exposure.
Absorb with inert material (e.g., sand, vermiculite) and collect for disposal.
Dispose of in accordance with local regulations.

Storage:
Store Farnesol Plus in a cool, dry, well-ventilated area away from incompatible materials (see SDS for specific details).
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and ignition sources.

Handling Cautions:
Avoid inhalation of vapors and direct contact with skin and eyes.
Use explosion-proof equipment in areas where vapors may be present.


Storage:

Temperature:
Store Farnesol Plus at temperatures between 15-25°C as recommended by the manufacturer.
Avoid exposure to extreme temperatures.

Containers:
Use approved containers made of compatible materials.
Check for leaks or damage in storage containers regularly.

Separation:
Store Farnesol Plus away from incompatible materials, including strong oxidizers.

Handling Equipment:
Use dedicated equipment for handling Farnesol Plus to avoid cross-contamination.
Ensure all handling equipment is in good condition.

Security Measures:
Restrict access to storage areas.
Follow all applicable local regulations regarding the storage of cosmetic ingredients.

Emergency Response:
Have emergency response equipment and materials readily available, including spill cleanup materials, fire extinguishers, and emergency eyewash stations.
FATTY ACIDS, C12-18 AND C18-UNSATD., REACTION PRODUCTS WITH TRIETHANOLAMINE
Chemical Name:FATTY ACID DIETHANOLAMIDE SynonymsFATTY ACID DIETHANOLAMIDE;Fatty acid-diethanolamine condensate CAS:68603-42-9
Fatty acid diethanolamide
Tridecyl Alcohol Ethoxylates; Lauryl Alcohol Ethoxylates; Ceto Stearyl Alcohol Ethoxylates, C 12 C 14 - FATTY ALCOHOL; C 12 C 18 - FATTY ALCOHOL; C 16 C 18 - FATTY ALCOHOL; FATTY ALCOHOL ETHER SULPHATE,SODIUM SALT
FATTY ALCOHOL ALKOXYLATE
Fatty alcohol alkoxylates (or long-chain alcohols) are usually high-molecular-weight, straight-chain primary alcohols, derived from natural fats and oils.
Fatty alcohol alkoxylates are a class of non-ionic surfactants that are derived from fatty alcohols.
Fatty alcohol alkoxylates are typically produced by reacting fatty alcohols (which are derived from natural fats and oils) with alkylene oxides, such as ethylene oxide (EO) or propylene oxide (PO).

CAS Number: 120313-48-6
EINECS Number: 639-733-1

Fatty alcohol alkoxylates act as surfactants, meaning they can lower the surface tension of liquids, allowing them to mix more easily.
These surfactants are commonly used in a variety of industrial and household products due to their emulsifying, wetting, dispersing, and detergent properties.
The term "alkoxylate" refers to the alkylene oxide groups attached to the fatty alcohol molecule during the manufacturing process.

The addition of these alkoxyl groups imparts water-solubility and other surfactant properties to the fatty alcohol.
The number of alkoxyl groups added during the ethoxylation or propoxylation process can vary, leading to different types of fatty alcohol alkoxylates.
For example, ethoxylates have ethylene oxide units, while propoxylates have propylene oxide units.

The ratio of these alkoxyl units determines the properties of the resulting surfactant.
This property makes them effective in various applications, including as emulsifiers, detergents, and wetting agents.
These surfactants are particularly useful in emulsifying oil and water, making them suitable for formulations such as emulsifiable concentrates in the agrochemical industry or in the production of emulsion-based personal care products.

Fatty alcohol alkoxylates are commonly found in household and industrial cleaning products due to their detergent properties.
They help to break down and remove dirt and grease.
In the textile and leather industries, fatty alcohol alkoxylates are used as wetting agents and emulsifiers in the processing of fibers and fabrics.

Fatty alcohol alkoxylates can be found in various personal care products, including shampoos, conditioners, and skin cleansers, where they contribute to the formulation's stability and foaming properties.
Fatty alcohol ethoxylates (FAE) are produced by ethoxylation, where ethylene oxide is added to the fatty alcohol.
Similarly, fatty alcohol propoxylates are produced by propoxylation, using propylene oxide.

The choice between ethoxylation and propoxylation influences the properties of the resulting alkoxylate.
Fatty alcohol alkoxylates can be tailored to specific applications by adjusting the hydrophilic-lipophilic balance (HLB).
The HLB value determines the balance between the hydrophilic (water-attracting) and lipophilic (oil-attracting) parts of the surfactant, influencing its emulsification and solubilization properties.
Fatty alcohol alkoxylates are generally considered biodegradable, especially those with a higher degree of ethoxylation.

Biodegradability is an important consideration to minimize environmental impact.
In addition to their emulsifying and wetting properties, fatty alcohol alkoxylates can contribute to the foaming characteristics of formulations.
This makes them suitable for use in products like shampoos and bath products.

Depending on the manufacturing process, fatty alcohol alkoxylates may exhibit polydispersity, meaning that the alkoxylate chains may have varying lengths.
This can impact the surfactant's performance in different applications.
The properties of fatty alcohol alkoxylates can be influenced by temperature.

For example, some ethoxylates may exhibit clouding or precipitation at lower temperatures, a phenomenon known as cloud point.
Fatty alcohol alkoxylates are generally compatible with hard water, which makes them suitable for use in cleaning products in areas with varying water hardness.
The solubility of fatty alcohol alkoxylates in different solvents can vary.

This property is essential for their effective use in various formulations.
Fatty alcohol alkoxylates are often used in combination with other surfactants to achieve synergistic effects.
The combination of different surfactants can enhance the overall performance of a formulation.

Like other chemical substances, fatty alcohol alkoxylates are subject to regulatory oversight.
Users should ensure compliance with regulations and guidelines relevant to their specific applications and regions.
These surfactants are used in the formulation of agrochemicals, such as herbicides, insecticides, and fungicides, to improve their dispersion and effectiveness.

Fatty alcohol alkoxylates are employed in the production of paints and coatings to enhance their stability, dispersibility, and wetting characteristics.
Fatty alcohol ethoxylates are available under the Galaxy MW series of products which are anionic surfactants derived from natural fatty alcohols.
These anionic surfactants (Ethoxylated lauryl alcohol) are applied in a wide variety of applications and their function is strongly dependent on the chemical composition.

The Hydrophilic/ Lipophilic Balance (HLB) determines which non-ionic surfactant is best for a certain application.
Detergents (wetting agents, emulsifiers), personal hygiene products (shampoos, skin softener, foam boosters, Viscosity builders), leather (degreasing, wetting), fabric paints, and agriculture (emulsifiers, spreading out) all use the HLB value to decide their qualities.
And all of these characteristics customized via Lauryl alcohol ethoxylate have numerous industrial applications, both commercial and household.

Galaxy Surfactants produces a thorough range of non-ionic fatty alcohol ethoxylates that are custom-made to meet the needs of certain moles and products.
Fatty Alcohol Ethoxylate is a clear liquid substance based on the components Fatty Alcohol (FA) from the oleochemical chain and Ethylene Oxide (EO) from the petrochemical chain.
The focus of HELM is on natural based FA produced from palm kernel oil or coconut oil with different carbon chains and EO compositions.

Due to the wide experience in the area of surfactants and the structured supply chain of HELM it is possible to offer a high quality product at competitive prices from different sources/ origins in different kind of packing.
The class of fatty alcohol alkoxylates describes surfactants that are synthesised by reaction of fatty alcohols with alkoxides such as ethylene oxide or propylene oxide or a combination of both as copolymers.
The fatty alcohol ethoxylates are the non-ionic surfactants which are widely used in washing detergents both domestic and industrial.

These are used as wetting and cleaning agents in cosmetics, agriculture, textile, paper, oil and various other process industries.
However the main application of these ethoxylated alcohols in cosmetics and textile industries is for emulsification and solubilizing agent.
Fatty alcohol ethoxylate is a bi-product formed from the ethoxylation of fatty alcohols.

In this ethoxylation process the fatty alcohol groups like lauryl alcohol, stearyl alcohol, behenyl alcohol, oleyl cetyl alcohol etc are made to react with ethylene oxide thereby leading to the formation of fatty alcohol ethoxylates like lauryl alcohol ethoxylate, stearyl alcohol ethoxylate, behenyl alcohol ethoxylate etc.
All of these ehtoxylate products vary in physical appearance and have different properties like pour point, cloud point, density, viscosity, and flash point depending on the level of ethoxylation process from which they are formed.

Fatty acid ethoxylates are formed from ethoxylation process where fatty acids are made to react with ethylene oxide.
This ethoxylation process is known as fatty acid ethoxylation.
The ethoxylate bi-products formed from this ethoxylation process are non ionic surface active agents used in domestic as well as industrial formulations.

These are widely applied in processes as emulsifying softeners, wetting agents, cleaning agents and dispersants.
The most popular application of these fatty acid ethoxylates is in textile industry.
Fatty alcohol alkoxylate is used as spin finishing agents in various textile formulations.

The Fatty alcohol alkoxylate based on stearic acid have applications in cosmetics industries as emulsifiers in oil-in-water type creams and lotions.
Likewise some of the popular variants of Fatty alcohol alkoxylate formulations used in industries are coconut fatty acid ethoxylate, lauric acid ethoxylate, oleic acid, myristic acid ethoxylates.
Rimpro India is one of the leading suppliers of surfactant and specialty chemicals in India.

Both household as well as industrial products including ethoxylates, glycols, emulsifiers, cosmetic self emulsifying waxes, oilfield chemicals, surface active agents and much more are offered at much economical costs by Rimpro.
Textile surfactants for applications like lubricating, dyeing, scouring, finishing are available here.
Fatty alcohol alkoxylate also offers surfactants for paper, rubber, leather, paints, cosmetics, pharmaceutical and refining industries.

Fatty alcohol alkoxylates are the largest family of nonionic surfactants.
They are highly useful in applications that serve multiple markets. Each consists of a hydrophobic group from oleochemical or petrochemical source combined with varying amount of ethylene oxide.
Oxiteno's line of Fatty alcohol alkoxylates includes an extensive range of linear and branched hydrophobes, as well as a broad range of degree of ethoxylation.

These act as wetting and solubilizing agents, detergents, dispersants, emulsifiers, emollients, and degreasers.
In organic chemistry, Fatty alcohol alkoxylate is a chemical reaction in which ethylene oxide (C2H4O) adds to a substrate.
Fatty alcohol alkoxylate is the most widely practiced alkoxylation, which involves the addition of epoxides to substrates.

Fatty alcohol alkoxylates, especially those with a high degree of ethoxylation, can be used as anti-foaming agents in certain industrial processes where foam formation is undesirable.
Fatty alcohol ethoxylates find application in the formulation of lubricants and metalworking fluids.
They can act as emulsifiers and improve the lubricity of these products.

Fatty alcohol alkoxylates are used as additives in paint and coating formulations to improve the dispersion of pigments and enhance the stability of the final product.
In addition to their primary use as emulsifiers, fatty alcohol alkoxylates can be employed to introduce hydrophobic characteristics to formulations, especially when dealing with water-in-oil emulsions.
The length of the alkoxylate chain, which is determined by the number of ethylene oxide or propylene oxide units added, can influence the physical and chemical properties of the fatty alcohol alkoxylate.

This can impact parameters such as cloud point, solubility, and viscosity.
Fatty alcohol alkoxylates are used in various personal care products, including conditioners and lotions, where they contribute to the emollient properties and overall formulation stability.
In the food industry, certain fatty alcohol alkoxylates may find use as emulsifying agents or surface-active agents in food processing applications.

Fatty alcohol alkoxylate's crucial to ensure compliance with food safety regulations.
Fatty alcohol alkoxylates are effective dispersing agents and are used to stabilize suspensions of solid particles in liquid formulations.
Fatty alcohol ethoxylates are used in textile finishing processes to impart softness to fabrics.

They can act as dispersing agents for textile dyes and finishes.
Fatty alcohol alkoxylates are utilized in the production of packaging materials, such as films and coatings, to improve their properties.
These surfactants are common ingredients in household and industrial cleaning products, including laundry detergents, dishwashing liquids, and all-purpose cleaners.

Fatty alcohol alkoxylates are often converted to related species called ethoxysulfates.
Fatty alcohol alkoxylates and ethoxysulfates are surfactants, used widely in cosmetic and other commercial products.
The process is of great industrial significance, with more than 2,000,000 metric tons of various ethoxylates produced worldwide in 1994.

The reaction proceeds by blowing ethylene oxide through the alcohol at 180 °C and under 1-2 bar of pressure, with potassium hydroxide (KOH) serving as a catalyst.
The process is highly exothermic (ΔH -92 kJ/mol of ethylene oxide reacted) and requires careful control to avoid a potentially disastrous thermal runaway.
The starting materials are usually primary alcohols as they react ~10-30x faster than do secondary alcohols.

Fatty alcohol alkoxylates are considered to be a high production volume (HPV) chemical by the US EPA.
Fatty alcohol alkoxylate is sometimes combined with propoxylation, the analogous reaction using propylene oxide as the monomer.
Both reactions are normally performed in the same reactor and may be run simultaneously to give a random polymer, or in alternation to obtain block copolymers such as poloxamers.

Propylene oxide is more hydrophobic than ethylene oxide and its inclusion at low levels can significantly affect the properties of the surfactant.
In particular ethoxylated fatty alcohols which have been 'capped' with ~1 propylene oxide unit are extensively marketed as defoamers.
Ethoxylated fatty alcohols are often converted to the corresponding organosulfates, which can be easily deprotonated to give anionic surfactants such as sodium laureth sulfate.

Being salts, ethoxysulfates exhibit good water solubility (high HLB value).
The conversion is achieved by treating Fatty alcohol alkoxylates with sulfur trioxide.
Although Fatty alcohol alkoxylates are by far the major substrate for ethoxylation, many nucleophiles are reactive toward ethylene oxide.

Primary amines will react to give di-chain materials such as polyethoxylated tallow amine.
The reaction of ammonia produces important bulk chemicals such as ethanolamine, diethanolamine, and triethanolamine.
As Fatty alcohol alkoxylate based surfactants are non-ionic they typically require longer ethoxylate chains than their sulfonated analogues in order to be water-soluble.

Fatty alcohol alkoxylate is sometimes combined with propoxylation, the analogous reaction using propylene oxide as the monomer.
Both reactions are normally performed in the same reactor and may be run simultaneously to give a random polymer, or in alternation to obtain block copolymers such as poloxamers.
Fatty alcohol alkoxylate is more hydrophobic than ethylene oxide and its inclusion at low levels can significantly affect the properties of the surfactant.

In particular Fatty alcohol alkoxylates which have been 'capped' with ~1 propylene oxide unit are extensively marketed as defoamers.
In this particular family, the hydrophobic moiety of the surfactant is the polyoxypropylene chain.
Examples synthesized on an industrial scale include octyl Fatty alcohol alkoxylate, polysorbate 80 and poloxamers.

Fatty alcohol alkoxylate is commonly practiced, albeit on a much smaller scale, in the biotechnology and pharmaceutical industries to increase water solubility and, in the case of pharmaceuticals, circulatory half-life of non-polar organic compounds.
In this application, ethoxylation is known as Fatty alcohol alkoxylate (polyethylene oxide is synonymous with polyethylene glycol, abbreviated as PEG).
Carbon chain length is 8-18 while the ethoxylated chain is usually 3 to 12 ethylene oxides long in home products.

They feature both lipophilic tails, indicated by the alkyl group abbreviation, R, and relatively polar headgroups, represented by the formula (OC2H4)nOH.
Fatty alcohol alkoxylates are not observed to be mutagenic, carcinogenic, or skin sensitizers, nor cause reproductive or developmental effects.
One byproduct of ethoxylation is 1,4-dioxane, a possible human carcinogen. Undiluted AEs can cause dermal or eye irritation.

As alcohol ethoxylate based surfactants are non-ionic they typically require longer ethoxylate chains than their sulfonated analogues in order to be water-soluble.
Examples synthesized on an industrial scale include Fatty alcohol alkoxylate, polysorbate 80 and poloxamers.
Ethoxylation is commonly practiced, albeit on a much smaller scale, in the biotechnology and pharmaceutical industries to increase water solubility and, in the case of pharmaceuticals, circulatory half-life of non-polar organic compounds.

In this application, ethoxylation is known as Fatty alcohol alkoxylate (polyethylene oxide is synonymous with polyethylene glycol, abbreviated as PEG).
Carbon chain length is 8-18 while the ethoxylated chain is usually 3 to 12 ethylene oxides long in home products.
They feature both lipophilic tails, indicated by the alkyl group abbreviation, R, and relatively polar headgroups, represented by the formula (OC2H4)nOH.

In aqueous solution, the level of irritation is dependent on the concentration.
Fatty alcohol alkoxylates are considered to have low to moderate toxicity for acute oral exposure, low acute dermal toxicity, and have mild irritation potential for skin and eyes at concentrations found in consumer products.
Toxicity to certain invertebrates has a range of EC50 values for linear AE from 0.1 mg/l to greater than 100 mg/l.

For branched Fatty alcohol alkoxylates, toxicity ranges from 0.5 mg/l to 50 mg/l.[16] The EC50 toxicity for algae from linear and branched AEs was 0.05 mg/l to 50 mg/l.
Acute toxicity to fish ranges from LC50 values for linear AE of 0.4 mg/l to 100 mg/l, and branched is 0.25 mg/l to 40 mg/l.
For invertebrates, algae and fish the essentially linear and branched Fatty alcohol alkoxylates are considered to not have greater toxicity than Linear AE.
Fatty alcohol alkoxylates are often converted to the corresponding organosulfates, which can be easily deprotonated to give anionic surfactants such as sodium laureth sulfate.

Being salts, ethoxysulfates exhibit good water solubility (high HLB value).
The conversion is achieved by treating ethoxylated alcohols with sulfur trioxide.
Fatty alcohol alkoxylates are nonionic surfactants made from various fatty alcohols ethoxylated and/or fatty acid propoxylated with various degrees of alkoxylation.

These nonionic surfactants make excellent emulsifiers.
Very useful in shampoos and bubble baths to control and adjust viscosity and lubricity.
Industrial ethoxylation is primarily performed upon alcohols.

Lower alcohols react to give glycol ethers which are commonly used as solvents, while longer fatty alcohols are converted to fatty alcohol ethoxylates (FAE's), which are a common form of nonionic surfactant.
The reaction typically proceeds by blowing ethylene oxide through the alcohol at 180 °C and under 1-2 bar of pressure, with potassium hydroxide (KOH) serving as a catalyst.
The process is highly exothermic (ΔH = -92 kJ/mol of ethylene oxide reacted) and requires careful control to avoid a potentially disastrous thermal runaway.

The starting materials are usually primary Fatty alcohol alkoxylates as they tend to react 10–30× faster than do secondary alcohols.
Typically 5-10 units of ethylene oxide are added to each alcohol, however Fatty alcohol alkoxylates can be more prone to ethoxylation than the starting alcohol, making the reaction difficult to control and leading to the formation of a product with varying repeat unit length (the value of n in the equation above).
Better control can be afforded by the use of more sophisticated catalysts, which can be used to generate narrow-range ethoxylates.

Fatty alcohol alkoxylates are considered to be a high production volume (HPV) chemical by the US EPA.
Hard surface cleaners are usually on acidic or alkaline systems and therefore necessitate a surfactant which is chemically stable at extreme pH.
They can be employed alone or in conjunction with anionic; cationic or other non-ionic surfactants.

Fatty alcohol alkoxylates (or longchain alcohols) are usually high-molecular-weight, straight-chain primary alcohols, derived from natural fats and oils.
They are colourless oily liquids or waxy solids (depending on the carbon numbers), although impure samples may appear yellow.
Fatty alcohol alkoxylate and alcohol ethoxysulfates (AES) are surfactants found in products such as laundry detergents, surface cleaners, cosmetics, agricultural products, textiles, and paint.

Uses:
Fatty alcohol alkoxylate is used as raw material for the manufacturer of sodium lauryl ether sulphate (SLES) Detergents: a base liquid and powder detergents, household cleaning agents, industrial cleaning agents.
Fatty alcohol alkoxylate is used as raw materials in shampoo, body gels and hand cleaners.
Fatty alcohol alkoxylate is used as scouring and wetting agents.

Fatty alcohol alkoxylate is used as emulsifiers in herbicides, Insecticides and fertilizers.
Fatty alcohol alkoxylate is used as wetting agents and improve absorbency.
Fatty alcohol alkoxylate is used as stabilizers for rubber.

Fatty alcohol alkoxylate is used as degreasing and tanning agents.
Fatty alcohol alkoxylate is used as wetting agents and dispersing agent.
Fatty alcohol alkoxylate is used in a wide variety of industrial and commercial settings.

Because these compounds are surfactants, they can be used whenever oily substances come into contact with water or a surface.
Fatty alcohol alkoxylate can be used as detergents, wetting agents, emulsifiers, degreasers and emollients in many lines of commercially available products and industrial practices.
They show excellent wetting, emulsifying, low-foaming, detergency, and cleaning properties and are most suitable for household and industrial cleaning, for the textile and leather industry, and in performance chemicals.

They are mainly used in cleaning agents, detergents, home care and emulsifier production.
Chemicals such as Fatty alcohol alkoxylates, SLES and SLS can also be manufactured from methyl esters.
Depending on the grade / type of fatty alcohols.

Fatty alcohol alkoxylate is an industrial process in which ethylene oxide is added to alcohols and phenols to give surfactants.
Fatty alcohol alkoxylates are produced by reacting alcohol with oxirane (ethene oxide).
The alcohol could be made from cracked petroleum (via ethane, propane and carbon monoxide) or from vegetable or animal oil and fats.

Fatty Alcohol Ethoxylates are used as hard surface cleaner, for sulphonation to Sodium Lauryl Ether Sulphates (SLES), detergents, cleaners, dishwashing, personal care e.g. showergel and hairshampoo, cosmetics, leather and textile processing as well as in the area of paints and agriculture.
Fatty alcohol alkoxylate is used in tiny amounts with other surfactants as a wetting agent and emulsifier for foamy toilet soaps.
Because it works as a highly active substance with low salt content and water, linear alkylbenzene sulfonic acid is used in the manufacture of coupling agents, farming fungus killer, household and industrial cleaners, herbicides and in emulsion polymerization.

Fatty acid alkoxylates used as non-ionic surfactants in home and industrial cleaning are synthesized by a reaction of fatty alcohols with alkoxides.
Analysing these copolymers is, however, a challenging task.
They can be characterized by their degree of alkoxylation, the arrangement of building blocks, the type of starter used and the endcapping.

Difficulties arise from the fact that they are often present in complex matrices, from the high polydispersity and from the presence of a large number of constitutional isomers depending on the degree of alkoxylation.
Fatty alcohol alkoxylates are popular surfactants used in industrial processes.
These are produced from ethoxylation process.

In an Fatty alcohol alkoxylate process ethylene oxide is made to react with compounds having labile hydrogen.
Fatty alcohols and fatty acids are the two popular categories of compounds which are usually used in industrial ethoxylation processes for formation of surfactants.
Block copolymers could be used as antifoams in different industrial sectors (paper, textile, ceramic), as low foam wetting agents in agro and ceramic sectors, as demulsifiers in oil & gas sector.

Fatty alcohol alkoxylates are commonly used in the formulation of household and industrial cleaning products, such as laundry detergents, dishwashing liquids, and all-purpose cleaners.
They contribute to the detergency and emulsification of dirt and grease.
Fatty alcohol alkoxylates are found in a variety of personal care products, including shampoos, conditioners, body washes, and facial cleansers.

They provide emulsification, foaming, and wetting properties.
Fatty alcohol alkoxylates are used in the formulation of agrochemicals, such as pesticides and herbicides, as emulsifiers.
They help in creating emulsifiable concentrates that can be easily mixed with water for application.

In the textile industry, fatty alcohol alkoxylates serve as wetting agents, emulsifiers, and dispersants.
They contribute to the even distribution of dyes and finishes on fabrics.
Fatty alcohol alkoxylates are used in the formulation of paints and coatings to improve dispersion of pigments and enhance the stability of the formulations.

Fatty alcohol alkoxylate is used in the formulation of metalworking fluids and lubricants to improve emulsification and lubricity.
In the food industry, certain fatty alcohol alkoxylates may be used as emulsifying agents or surface-active agents in food processing applications.
Care must be taken to comply with food safety regulations.

Fatty alcohol alkoxylates can be used in the formulation of adhesives and sealants to improve wetting and dispersing properties.
Some types of fatty alcohol alkoxylates are used as anti-foaming agents in industrial processes where foam formation is undesirable.
Fatty alcohol ethoxylates are used as softeners in textile finishing processes to impart a soft feel to fabrics.

In the pharmaceutical industry, these surfactants may be used in certain formulations, such as emulsions and creams.
Fatty alcohol alkoxylates can be used in the production of packaging materials, such as films and coatings, to improve their properties.
Beyond basic personal care products, fatty alcohol alkoxylates are utilized in various cosmetic and toiletry formulations, contributing to the stability and sensory characteristics of the products.

Fatty alcohol alkoxylates are used in the formulation of printing inks to disperse pigments and improve the ink's flow properties.
In the printing industry, these surfactants may be added as additives to inks and coatings to enhance their properties, such as adhesion and wetting.
Fatty alcohol alkoxylates can be used as additives in concrete formulations to improve the workability and dispersion of admixtures.

In the pulp and paper industry, these surfactants are employed in various stages of paper production, including as dispersing agents and in the de-inking process.
Certain types of fatty alcohol alkoxylates may find use in the formulation of firefighting foams due to their ability to create stable emulsions.
In the oil and gas industry, fatty alcohol alkoxylates can be used in the formulation of drilling fluids and other oilfield chemicals.

Fatty alcohol alkoxylates may be used as excipients in pharmaceutical formulations, helping to improve the solubility and stability of certain drug compounds.
These surfactants are utilized in the formulation of anti-corrosion products, where they can enhance the dispersion of corrosion inhibitors.
Fatty alcohol alkoxylates may be used in the formulation of coolants and antifreeze products, contributing to their stability and dispersion properties.

In polymer processing, these surfactants may be employed as processing aids to improve the dispersion of additives and fillers.
Fatty alcohol alkoxylates are used in the formulation of cleansing wipes and towelettes, providing emulsifying and cleaning properties.
In paper recycling processes, fatty alcohol alkoxylates can be used as de-inking agents to facilitate the removal of ink from recycled paper.

These surfactants may be included in the formulation of mold release agents to improve the release of molded products from molds.
Fatty alcohol alkoxylates are employed as textile auxiliaries to impart specific characteristics to fabrics, such as softness and antistatic properties.
They are used in the formulation of automotive care products, including car shampoos and cleaners, due to their emulsifying and cleaning capabilities.

Fatty alcohol alkoxylates may be used in bioremediation products to enhance the dispersion and solubility of certain remediation agents.
With a growing focus on sustainability, there is ongoing research into the use of eco-friendly fatty alcohol alkoxylates in various formulations.

Human health Profile:
Fatty alcohol alkoxylates are not observed to be mutagenic, carcinogenic, or skin sensitizers, nor cause reproductive or developmental effects.
One byproduct of Fatty alcohol alkoxylate is 1,4-dioxane, a possible human carcinogen.
Undiluted Fatty alcohol alkoxylates can cause dermal or eye irritation.

In aqueous solution, the level of irritation is dependent on the concentration.
Fatty alcohol alkoxylates are considered to have low to moderate toxicity for acute oral exposure, low acute dermal toxicity, and have mild irritation potential for skin and eyes at concentrations found in consumer products.
Recent studies have found dried Fatty alcohol alkoxylate residues similar to what would be found on restaurant dishes (as effective concentrations from 1:10,000 to 1:40,000) killed epithelial intestinal cells at high concentrations.

Lower concentrations made cells more permeable and prone to inflammatory response.
Fatty alcohol alkoxylates may cause skin and eye irritation upon direct contact.
Proper personal protective equipment, such as gloves and goggles, should be worn when handling concentrated solutions.

Inhalation of vapors or mists from fatty alcohol alkoxylates may cause respiratory irritation.
Adequate ventilation should be provided in areas where these substances are handled, and respiratory protection may be necessary in certain situations.
Some individuals may be sensitive or allergic to certain components of fatty alcohol alkoxylates.

Skin testing and medical advice should be sought if there are concerns about potential sensitization.
While fatty alcohol alkoxylates are generally considered biodegradable, their release into the environment, especially in large quantities, should be managed according to environmental regulations.

The toxicity of fatty alcohol alkoxylates can vary depending on the specific formulation, alkoxyl chain length, and other factors.
While many are designed to be safe for intended uses, exposure to high concentrations may pose risks.

Synonyms:
Alcohols, C12-15-branched and linear, ethoxylated propoxylated
120313-48-6
DTXSID90106121
Ethoxylated Fatty Alcohols
Ethoxylated Alkyl Alcohols
Ethoxylated Fatty Alkyls
FAE
Propoxylated Fatty Alcohols
Propoxylated Alkyl Alcohols
Propoxylated Fatty Alkyls
Alkyl Alcohol Ethoxylates
Alkyl Alcohol Propoxylates
Alcohol Ethoxylates and Propoxylates
Alkoxylated Fatty Alcohol Surfactants
Alkoxylated Alkyl Alcohols
PEGylated Fatty Alcohols
Fatty Alcohol PEG Esters
FATTY ALCOHOL ETHOXYLATE
FATTY ALCOHOL ETHOXYLATE = n-PROPYL ACETATE


CAS Number: 109-60-4
EC Number: 203-686-1
Formula: C5H10O2


Fatty alcohol ethoxylates are the non-ionic surfactants which are widely used in washing detergents both domestic and industrial.
These are used as wetting and cleaning agents in cosmetics, agriculture, textile, paper, oil and various other process industries.
However the main application of these ethoxylated alcohols in cosmetics and textile industries is for emulsification and solubilizing agent.
Fatty alcohol ethoxylate is a bi-product formed from the ethoxylation of fatty alcohols.


In this ethoxylation process the fatty alcohol groups like lauryl alcohol, stearyl alcohol, behenyl alcohol, oleyl cetyl alcohol etc are made to react with ethylene oxide thereby leading to the formation of fatty alcohol ethoxylates like lauryl alcohol ethoxylate, stearyl alcohol ethoxylate, behenyl alcohol ethoxylate etc.
All of these ehtoxylate products vary in physical appearance and have different properties like pour point, cloud point, density, viscosity, and flash point depending on the level of ethoxylation process from which they are formed.


Fatty Alcohol Ethoxylate normal propyl acetate (also known as n-propyl acetate or 1-propyl acetate) is an organic compound with a molecular formula of C5H10O2.
Fatty alcohol ethoxylate is commonly used as a solvent in coatings and printing inks.
Fatty alcohol ethoxylate is a clear, colourless liquid that has a distinguishable acetate odour.


Fatty alcohol ethoxylate is highly flammable with a flash point of 14° C and a flammability rating of 3.
Fatty alcohol ethoxylate is highly miscible with all common organic solvents (alcohols, ketones, glycols, esters) but has only slight miscibility in water.
Fatty Alcohol Ethoxylate is a clear liquid substance based on the components Fatty Alcohol (FA) from the oleochemical chain and Ethylene Oxide (EO) from the petrochemical chain.


Industrial ethoxylation is primarily performed upon fatty alcohols in order to generate Fatty alcohol ethoxylates (FAE's), which are a common form of nonionic surfactant (e.g. octaethylene glycol monododecyl ether).
Such alcohols may be obtained by the hydrogenation of fatty acids from seed oils, or by hydroformylation in the Shell higher olefin process.
The reaction proceeds by blowing ethylene oxide through the alcohol at 180 °C and under 1-2 bar of pressure, with potassium hydroxide (KOH) serving as a catalyst.


The process is highly exothermic (ΔH -92 kJ/mol of ethylene oxide reacted) and requires careful control to avoid a potentially disastrous thermal runaway.
ROH + n C2H4O → R(OC2H4)nOH
The starting materials are usually primary alcohols as they tend to react 10–30× faster than do secondary alcohols.


Typically 5-10 units of ethylene oxide are added to each alcohol, however ethoxylated alcohols can be more prone to ethoxylation than the starting alcohol, making the reaction difficult to control and leading to the formation of a product with varying repeat unit length (the value of n in the equation above).
Better control can be afforded by the use of more sophisticated catalysts, which can be used to generate narrow-range ethoxylated.


Fatty alcohol ethoxylate is expected to witness a significant growth with a CAGR of ~4.2% between 2016 and 2030.
These transparent liquid substance, Fatty alcohol ethoxylated, are made from ethylene oxide and fatty alcohol.
Among all, household and personal care industry are the largest market segments in terms of end use industry.
Fatty alcohol ethoxylate is expected to witness significant growth with a CAGR of ~4.2% between 2016 and 2030.


On the basis of region, Fatty alcohol ethoxylates market segmentation includes the current and estimate demand for Europe, Latin America, North America, Asia Pacific, and Middle East & Africa.
This segmentation includes demand for separate industries in all the regions, for instance, Asia Pacific has the biggest market for fatty alcohol ethoxylates due to high utilization in household, personal care, and paint & coatings industry, especially in China, India, and Japan.


The production process starts with a homologous series of fatty alcohol compounds typically from lauryl alcohol (C12) to stearyl alcohol (C18).
These compounds are reacted with ethylene oxide, which gives a second homologous series of ethoxylates at the other side of the molecule.
To monitor the quality and composition of the technical product, it is important to have a separation method in hand which is able to separate both homologous series, the fatty alcohol component and the successive series of ethoxylated units.


The only separation technology which can fulfill this requirement is comprehensive 2-dimensional liquid chromatography by the combination of the selectivity of a HILIC and an RP separation.
The other challenge is to find the right detection method because UV detection is not possible due to the lack of UV activities of these compounds.
Typically an Evaporative Light Scattering Detector (ELSD) is used for such a class of non-UV active and nonvolatile compounds.


In addition, this is a cost-effective detection method useful for technical quality control.
The broad range of products, which is adapted very individually to your particular requirements, is based on short- to long-chained (C4 to over C20), linear (native and Ziegler), mainly linear (oxo-) and branched (iso-, Guerbet), saturated and unsaturated alcohols, combined with the precise setting of the desired degree of ethoxylation.


Natural fatty alcohols, differs in its distribution of carbon chains and hence can provide different ethoxylated alcohol structures and properties depending on the plant from which they were extracted.
Example of natural fatty alcohols are lauryl alcohol ethoxylates.
Fatty Alcohol Ethoxylate normal propyl acetate (also known as n-propyl acetate or 1-propyl acetate) is an organic compound with a molecular formula of C5H10O2.
Ethoxylated alcohols are considered to be a high production volume (HPV) chemical by the US EPA.



USES and APPLICATIONS of FATTY ALCOHOL ETHOXYLATE:
Cosmetic Uses of Fatty Alcohol Ethoxylate: perfuming agents, and solvents.
Fatty Alcohol Ethoxylate is commonly used as a solvent in coatings and printing inks.
Fatty alcohol ethoxylate is applied in a wide variety of applications and its function is strongly dependent on the chemical composition.
The Hydrophilic/ Lipophilic Balance (HLB) determines which non-ionic surfactant is best for a certain application.
Fatty alcohol ethoxylate is used detergents (wetting agents, emulsifiers), personal hygiene products (shampoos, skin softener, foam boosters,

Viscosity builders), leather (degreasing, wetting), fabric paints, and agriculture (emulsifiers, spreading out) all use the HLB value to decide their qualities.
Fatty Alcohol Ethoxylates are used as hard surface cleaner, for sulphonation to Sodium Lauryl Ether Sulphates (SLES), detergents, cleaners, dishwashing, personal care e.g. showergel and hairshampoo, cosmetics, leather and textile processing as well as in the area of paints and agriculture.


Fatty Alcohol Ethoxylates (FAE) are non-ionic environmentally friendly and “green” surfactants primarily used in detergents, personal care e.g. for shampoo, as well as for textile and leather processing.
Fatty alcohol ethoxylates are fatty alcohol polyglycol ethers, which is majorly used in detergents, personal care products like shampoo, as well as for textile and leather industry.


Fatty alcohol ethoxylate is good wetting agent for Suspension concentrate (SC), Soluble Liquid concentrate (SL), Suspoemulsion (SE), Wettable Powder (WP) and Water Dispersible Granules (WG)
On the basis of end use industries, the market is segmented into textiles, agriculture, personal care, household, paper, and others.
Fatty alcohol ethoxylate is used as an emulsifier and surfactant in the formulation of a variety of bath, eye, facial, hair, cleansing and sunscreen products, as well as cuticle softeners, deodorants and moisturizing products, biodegradable emulsifier for mineral oils and surfactant in production.


Fatty alcohol ethoxylates are good emulsifiers for different applications and have an excellent eco-toxicological profile (no hazard label needed).
In applications where foam is unwanted, an important advantage over the corresponding fatty alcohol ethoxylates is the reduced foaming power.
Fatty alcohol ethoxylated is used in production of Emulsion Polyvinyl Chloride where their main function is as viscosity depressants in the final extrusion of the article.


Fatty alcohol ethoxylates belong to the class of non-ionic surfactants and are used for a large variety of consumer products like cosmetics, cleaners, colors, plant protection, textiles and other industrial applications.
Fatty alcohol ethoxylated is a non-ionic surfactant which are widely used in washing detergents both domestic and industrial.
Fatty alcohol ethoxylate is a bi-product formed from the ethoxylation of fatty alcohols.


Fatty alcohol ethoxylate is surfactant, which are commonly used as components of cleaning detergents and formulation in the industrial, commercial, and domestic markets.
Fatty alcohol ethoxylates find large-scale applications in detergents (wetting agents, emulsifiers, personal hygiene products (shampoos, emollients, foam boosters, Viscosity builders), leather (degreasing, wetting), textile paints and agriculture (emulsifiers, dispersion) process.



PHYSICAL and CHEMICAL PROPERTIES of FATTY ALCOHOL ETHOXYLATE:
Appearance Form: clear, liquid
Color: colorless
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point:
Melting point/range: -95 °C - lit.
Initial boiling point and boiling range: 102 °C - lit.
Flash point 14 °C - closed cup
Evaporation rate: No data available


Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 8 %(V)
Lower explosion limit: 1,7 %(V)
Vapor pressure: 33 hPa at 20 °C
Vapor density: 3,53 - (Air = 1.0)
Density: 0,888 g/cm3 at 25 °C - lit.
Relative density: No data available
Water solubility: soluble
Partition coefficient: n-octanol/water: log Pow: 1,23
Autoignition temperature: No data available
Decomposition temperature: No data available


Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 24,3 mN/m at 20 °C
Relative vapor density: 3,53 - (Air = 1.0)
Appearance: colorless clear liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: Yes
Specific Gravity: 0.88000 to 0.90000 @ 25.00 °C.
Pounds per Gallon - (est).: 7.322 to 7.489


Refractive Index: 1.37800 to 1.38800 @ 20.00 °C.
Melting Point: -95.00 °C. @ 760.00 mm Hg
Boiling Point: 101.00 to 102.00 °C. @ 760.00 mm Hg
Boiling Point: 32.00 to 33.00 °C. @ 50.00 mm Hg
Acid Value: 1.00 max. KOH/g
Vapor Pressure: 35.223000 mmHg @ 25.00 °C. (est)
Vapor Density: 3.5 ( Air = 1 )
Flash Point: 55.00 °F. TCC ( 12.78 °C. )
logP (o/w): 1.240
Soluble in: alcohol, water, 18900 mg/L @ 20 °C (exp)
Insoluble in: water



FIRST AID MEASURES of FATTY ALCOHOL ETHOXYLATE:
-Description of first-aid measures:
*General advice:
Consult a physician.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
*If swallowed:
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of FATTY ALCOHOL ETHOXYLATE:
-Personal precautions, protective equipment and emergency procedures:
Use personal protective equipment.
-Environmental precautions:
Do not let product enter drains.



FIRE FIGHTING MEASURES of FATTY ALCOHOL ETHOXYLATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
Use water spray to cool unopened containers.



EXPOSURE CONTROLS/PERSONAL PROTECTION of FATTY ALCOHOL ETHOXYLATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection.
Face shield and safety glasses.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Splash contact:
Material: butyl-rubber
Minimum layer thickness: 0,3 mm
Break through time: 110 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of FATTY ALCOHOL ETHOXYLATE:
-Precautions for safe handling:
*Advice on safe handling:
Avoid contact with skin and eyes.
*Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of FATTY ALCOHOL ETHOXYLATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available



SYNONYMS:
1-acetoxypropane
1-propyl acetate
acetate of propyl
acetic acid normal-propyl ester
acetic acid n-propyl ester
acetic acid propyl ester
acetic acid, 1-propyl ester
acetic acid, propyl ester
normal propyl acetate
n-Propyl acetate
propylethanoate
FATTY ALCOHOL ETHOXYLATES
Fatty alcohol ethoxylates are a clear liquid substance based on the components Fatty Alcohol (FA) from the oleochemical chain and Ethylene Oxide (EO) from the petrochemical chain.


CAS Number: 109-60-4
EC Number: 203-686-1
Formula: C5H10O2



1-acetoxypropane, 1-propyl acetate, acetate of propyl, acetic acid normal-propyl ester, acetic acid n-propyl ester, acetic acid propyl ester, acetic acid, 1-propyl ester, acetic acid, propyl ester, normal propyl acetate, n-Propyl acetate, propylethanoate, C12-C14 Alcohol, Lauryl Alcohol Ethoxylates, Polyoxyethylene Alcohol/ Fatty Alcohol Polyglycols Ethers, Fatty Alcohol Ethoxylates, Ethoxylated Fatty Alcohols, Fatty Alcohol Polyglycol Ethers, Fatty Alcohol Polyoxyethylene Ethers, Polyethylene Fatty Alcohol Ethers, Fatty Alcohol Polyglycol Ethers,



Fatty alcohol ethoxylates are a clear liquid substance based on the components Fatty Alcohol (FA) from the oleochemical chain and Ethylene Oxide (EO) from the petrochemical chain.
The focus of HELM is on natural based FA produced from palm kernel oil or coconut oil with different carbon chains and EO compositions.


Due to the wide experience in the area of surfactants and the structured supply chain of HELM it is possible to offer a high quality product at competitive prices from different sources/ origins in different kind of packing.
Fatty alcohol ethoxylates are anionic surfactants derived from natural fatty alcohols.


These anionic surfactants (Ethoxylated lauryl alcohol) are applied in a wide variety of applications and their function is strongly dependent on the chemical composition.
The Hydrophilic/ Lipophilic Balance (HLB) determines which non-ionic surfactant is best for a certain application.


Fatty alcohol ethoxylates are surfactant, which are commonly used as components of cleaning detergents and formulation in the industrial, commercial, and domestic markets.
Example of natural fatty alcohols are lauryl alcohol ethoxylated.


Fatty alcohol ethoxylates are non-ionic surfactants produced by adding ethylene oxide (EO) to Linear Fatty Alcohols.
Fatty alcohol ethoxylates are the non-ionic surfactants which are widely used in washing detergents both domestic and industrial.
Fatty alcohol ethoxylates are used as wetting and cleaning agents in cosmetics, agriculture, textile, paper, oil and various other process industries.


However the main application of these ethoxylated alcohols in cosmetics and textile industries is for emulsification and solubilizing agent.
Fatty alcohol ethoxylates are a bi-product formed from the ethoxylation of fatty alcohols.
In this ethoxylation process the fatty alcohol groups like lauryl alcohol, stearyl alcohol, behenyl alcohol, oleyl cetyl alcohol etc are made to react with ethylene oxide thereby leading to the formation of Fatty alcohol ethoxylates like lauryl alcohol ethoxylate, stearyl alcohol ethoxylate, behenyl alcohol ethoxylate etc.


All of these ehtoxylate products vary in physical appearance and have different properties like pour point, cloud point, density, viscosity, and flash point depending on the level of ethoxylation process from which they are formed.
Fatty alcohol ethoxylates are a nonionic surfactant that is comprised of different degrees of alcohol ethoxylates obtained from the reaction of lauryl alcohol derived from natural and renewable sources with ethylene oxide (EO).


Fatty alcohol ethoxylates are a transparent liquid in form.
Due to its nonionic classification, Fatty alcohol ethoxylates have very good stability to salts, water hardness, solvents, acids and alkalis.
It is an excellent emulsifying agent with detergent properties and there are many advantages for using Fatty alcohol ethoxylates.


For one, Fatty alcohol ethoxylates do not contain nonylphenol ethoxylate (NPE) which makes it readily biodegradable.
Common applications of Fatty alcohol ethoxylates include personal care, home care and I&I and oil and gas.
The percent active part of Fatty alcohol ethoxylates are 90%.


Fatty alcohol ethoxylates are produced by the reaction of ethylene oxide with fatty alcohol.
Fatty alcohol ethoxylates is a non-ionic surfactant.
Fatty alcohol ethoxylates's appearance is white to light yellow flake solid.


Fatty alcohol ethoxylates are easily soluble in water, ethanol, ethylene glycol, etc. with cloud point.
The pH value of 1% aqueous solution of Fatty alcohol ethoxylates is neutral, and the HLB value is 18-19.
Fatty alcohol ethoxylates can resist acid, alkali, hard water, heat and heavy metal salt.


Fatty alcohol ethoxylates have strong levelness, retarding, permeability and diffusivity for various dyes.
Contrary to negatively charged cleaners (anionic surfactants) and positively charged cleaners (cationics), Fatty alcohol ethoxylates have no charge.
By ethoxylating fatty alcohols (adding an ethoxy group –O-C2H5) an accessible oxygen atom comes available.


The oxygen atom forms so called hydrogen bridges with the water molecules.
This way, without a charge, still a hydrophilic end is added to the fatty alcohol molecule.
Fatty alcohol ethoxylates remain non-ionic, and therefore less aggressive in their cleaning.


This explains their mild behaviour.
Fatty alcohol ethoxylates are characterised by the length of its fat-alcohol chain and by how many ethoxy groups are attached to that chain.
The length of the (dirt dissolving) fatty chain is indicated by the number of C-atoms (“C12-C18” means chains of 12 to 18 C-atoms).


The number of (water binding) ethoxy groups is depicted by the amount of “mol EO”, a measure for the number of molecules Ethylene Oxide.
Fatty alcohol ethoxylates are ideal for use in liquid detergents.
As they are non-ionics, having no charge, these raw materials result in mild cleaners, such as wool detergents.


The mildest types are those with a linear C-chain (no branches).
These are also optimally broken down biologically.
Just like we, bacteria rather not place their teeth in products with complex 3-dimensional structures.


A “bar” of C-chains is easier consumed.
Fatty alcohol ethoxylates are nonionic surfactants produced bythe reaction of ethylene oxide (EO) with linear, branched, secondary, or oxo alcohols.
The alcohol structure of Fatty alcohol ethoxylates consists of an alkyl chain ranging from 6-18 Carbon atoms.



USES and APPLICATIONS of FATTY ALCOHOL ETHOXYLATES:
Fatty alcohol ethoxylates are used as hard surface cleaner, for sulphonation to Sodium Lauryl Ether Sulphates (SLES), detergents, cleaners, dishwashing, personal care e.g. showergel and hairshampoo, cosmetics, leather and textile processing as well as in the area of paints and agriculture.
Fatty alcohol ethoxylates are used Detergents (wetting agents, emulsifiers), personal hygiene products (shampoos, skin softener, foam boosters, Viscosity builders), leather (degreasing, wetting), fabric paints, and agriculture (emulsifiers, spreading out) all use the HLB value to decide their qualities.


Fatty alcohol ethoxylates find large-scale applications in detergents (wetting agents, emulsifiers, personal hygiene products (shampoos, emollients, foam boosters, Viscosity builders), leather (degreasing, wetting), textile paints and agriculture (emulsifiers, dispersion) process.
Surfactants: Fatty alcohol ethoxylates are used as raw material for the manufacturer of sodium lauryl ether sulphate (SLES)


Detergents: Fatty alcohol ethoxylates are a base liquid and powder detergents, household cleaning agents, industrial cleaning agents.
Cosmetics & Personal care: Fatty alcohol ethoxylates are used as raw materials in shampoo, body gels and hand cleaners.
Textiles: Fatty alcohol ethoxylates are used as scouring and wetting agents.


Agriculture: Fatty alcohol ethoxylates are used as emulsifiers in herbicides, Insecticides and fertilizers.
Paper: Fatty alcohol ethoxylates are used as wetting agents and improve absorbency.
Rubber: Fatty alcohol ethoxylates are used as stabilizers for rubber.


Paint: Fatty alcohol ethoxylates are used as wetting agents and dispersing agent.
Fatty alcohol ethoxylates are excellent Oil / water soluble detergents, emulsifier / co - emulsifier, wetting / cleaning & dispersing agents, intermediate for suphation and find application in various industries such as Textile, Detergent, Agrochemical, Emulsion, personel care, Emulsion Polymerisation & Paints.


Fatty alcohol ethoxylates are most commonly used in the formulation of paints and coatings, textile and paper processing aids, and various household, industrial and institutional products.
Leather: Fatty alcohol ethoxylates are used as degreasing and tanning agents.

Four factors determine the physical and chemical properties of these surfactants: carbon chain length, carbon chain structure, degree of ethoxylation, and hydrophile-lipophile balance (HLB).
As these attributes change, the physical and chemical attributes of the surfactants change.


There are many different options to choose from within this group of products.
Each Fernol Fatty alcohol ethoxylates has a different level of wetting and emulsifying capability.
Key applications of Fatty alcohol ethoxylates: Leather processing, Cleaning products, Agricultural, Cosmetic products, Paint and Coatings, and Rubber.


End-use applications of Fatty alcohol ethoxylates include hand dish washing liquids, shampoos, soaps, shower gels, foaming control agents, textile applications and specialty surfactants.
Fatty alcohol ethoxylates can be used together with various surfactants and dyes.



PROPERTIES AND USES OF FATTY ALCOHOL ETHOXYLATES:
1. Fatty alcohol ethoxylates are colorless transparent liquid or white cream.
2. Fatty alcohol ethoxylates are soluble in water and many kinds of organic solvents.
3. Fatty alcohol ethoxylates have good emulsification, dispersion, moisturing and decontamination capacity; Resistant to acid and alkali; Can be used to produce emulsifier, defoamer, solutizer and degreaser.



BENEFITS OF FATTY ALCOHOL ETHOXYLATES:
*Superior wetting
*Excellent oily soil removal
*Rapid dissolution and good rinsibility
*Low odour
*Excellent formulation and handling properties
*Readily biodegradable



FEATURES OF LINEAR FATTY ALCOHOL ETHOXYLATES ARE:
*Mild cleaners (wool, face, hands)
*Emulsifying (avoid sagging of other ingredients, such as fragrances and colourants in the end product)
*Dissolving (hydrophobic ingredients are kept in solution by Fatty alcohol ethoxylates in a water based end product)
*Wetting of surfaces (so the cleaning job by the end product becomes more effective, or by enhancing the moisturizing job of skin and hair –conditioner-cosmetics)
*Fatty alcohol ethoxylates are stable up to 130oC and within a broad pH range.



PHYSICAL and CHEMICAL PROPERTIES of FATTY ALCOHOL ETHOXYLATES:
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 8 %(V)
Lower explosion limit: 1,7 %(V)
Vapor pressure: 33 hPa at 20 °C
Vapor density: 3,53 - (Air = 1.0)
Density: 0,888 g/cm3 at 25 °C - lit.
Relative density: No data available
Water solubility: soluble
Partition coefficient: n-octanol/water: log Pow: 1,23
Autoignition temperature: No data available
Decomposition temperature: No data available
Refractive Index: 1.37800 to 1.38800 @ 20.00 °C.
Melting Point: -95.00 °C. @ 760.00 mm Hg
Boiling Point: 101.00 to 102.00 °C. @ 760.00 mm Hg

Boiling Point: 32.00 to 33.00 °C. @ 50.00 mm Hg
Acid Value: 1.00 max. KOH/g
Vapor Pressure: 35.223000 mmHg @ 25.00 °C. (est)
Vapor Density: 3.5 ( Air = 1 )
Flash Point: 55.00 °F. TCC ( 12.78 °C. )
logP (o/w): 1.240
Soluble in: alcohol, water, 18900 mg/L @ 20 °C (exp)
Insoluble in: water
Appearance Form: clear, liquid
Color: colorless
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point:
Melting point/range: -95 °C - lit.

Initial boiling point and boiling range: 102 °C - lit.
Flash point 14 °C - closed cup
Evaporation rate: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 24,3 mN/m at 20 °C
Relative vapor density: 3,53 - (Air = 1.0)
Appearance: colorless clear liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: Yes
Specific Gravity: 0.88000 to 0.90000 @ 25.00 °C.
Pounds per Gallon - (est).: 7.322 to 7.489



FIRST AID MEASURES of FATTY ALCOHOL ETHOXYLATES:
-Description of first-aid measures:
*General advice:
Consult a physician.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
*If swallowed:
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of FATTY ALCOHOL ETHOXYLATES:
-Personal precautions, protective equipment and emergency procedures:
Use personal protective equipment.
-Environmental precautions:
Do not let product enter drains.



FIRE FIGHTING MEASURES of FATTY ALCOHOL ETHOXYLATES:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
Use water spray to cool unopened containers.



EXPOSURE CONTROLS/PERSONAL PROTECTION of FATTY ALCOHOL ETHOXYLATES:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection.
Face shield and safety glasses.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Splash contact:
Material: butyl-rubber
Minimum layer thickness: 0,3 mm
Break through time: 110 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of FATTY ALCOHOL ETHOXYLATES:
-Precautions for safe handling:
*Advice on safe handling:
Avoid contact with skin and eyes.
*Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of FATTY ALCOHOL ETHOXYLATES:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available


Fatty alcohol ethoxylates and blends
Fatty Amine Polyoxyethylene Ether; cas no:266345-92-7
FATTY AMINE ETHOXYLATE
DESCRIPTION:
In chemistry, a fatty amine is loosely defined as any amine possessing a mostly linear hydrocarbon chain of eight or more carbon atoms.
Fatty Amine Ethoxylates are typically prepared from the more abundant fatty acids, with vegetable or seed-oils being the ultimate starting material.
As such they are often mixtures of chain lengths, ranging up to about C22.
Fatty Amine Ethoxylate can be classified as oleochemicals.
Commercially important members include coco amine, oleylamine, tallow amine, and soya amine.

These compounds and their derivatives are used as fabric softeners, froth flotation agents (purification of ores), corrosion inhibitors, lubricants and friction modifiers.
Fatty Amine Ethoxylate is also the basis for a variety of cosmetic formulations.

Fatty Amine Ethoxylate is nonionic surfactants resulting from the reaction of alkylamines with ethylene oxide.
Fatty Amine Ethoxylate plays an important role in the Oil & Gas, Crop Solutions, and textile processing markets.
Fatty Amine Ethoxylate acts as solubilizers, wetting agents, anti-corrosives, and adjuvants.

Fatty Amine Ethoxylate category include oleyl amine ethoxylates and coco amine ethoxylates, and are marketed under the AMINOX series.





Depending on the degree of ethoxylation, the manufacturing conditions and the pH adjustment, ethoxylates based on primary amines display, to a more or less pronounced extent, the characteristics of cationic surfactans.

The affinity to various different surfaces that tend to be anionics is particularly high, a property which can be utilised beneficially in the textile and leather processing industries, but also in metal treatment (antistatics, improved grip, hydrophobing, etc.).
Fatty Amine Ethoxylate and the alkylpropylene diamine ethoxylates which we supply can also be used as emulsifieres, for example in the processing of mineral oil and bitumen.

Generally derived from linoleic acid, fatty amine ethoxylates have many applications.
Fatty Amine Ethoxylate can be used as solvent-removable detergents and can also be a penetrant and lubricant.
Other applications include paper making and paint.
Fatty Amine Ethoxylates are non-toxic and have good flame-retardant properties.

Typical uses for fatty amine ethoxylates include wetting and scattering agents, sanitisers, anticorrosion agents, and lubricants.
Fatty amine ethoxylates are used in a wide range of industries including the food, beverage, and healthcare industries.

The primary fatty amine is used as a cationic and amphoteric surfactant.
Fatty Amine Ethoxylate is also used as a corrosion inhibitor and a release agent for moulded rubber parts.
Its secondary form is used as a lubricant, anti-caking agent, and fuel additives.
Fatty amine ethoxylates are produced by hydrogenation of unsaturated fatty nitriles and are more water-dispersible.

As a corrosion inhibitor, fatty amine thioesters can prevent iron corrosion by providing a sulfur-containing ethoxylated polyolefin.
This thiocyanate is used to protect ferrous metals in severe environments such as acidic, salty, and high-temperature environments.


CHEMICAL AND PHYSICAL PROPERTIES OF FATTY AMINE ETHOXYLATE:
Storage: Room Temperature
Smell: Sharp
Density: 0.86 ~ 0.95 Gram per cubic meter (g/m3)
Purity: 98 %
Product Type: ACID THICKENER
Appearance: yellow to reddish viscous liquid
Grade: acid thickener
Physical Form: Liquid
Ingredients: fatty amine
Ph Level: 8 ~ 10
Melting Point: 15 C
Solubility: water
Shelf Life: 1-3 Years
Usage:
Formulation Suggestions for Toilet cleaner Water :- 65.5%
Shivcide7030( AT) :- 2.5%
HCL 32 % :- 30 %
Biocide shiv30 :- 2 %
Pefume :- 0.1%
Colour :- 0.1%
Properties: Fatty amine ethoxylate yellow to reddish viscous liquid


USAGE OF FATTY AMINE ETHOXYLATE:
Fatty amine ethoxylates are used in numerous industries and applications.
The fatty amine ethoxylates are derived from coconut, stearyl, tallow, and oleyl amines.
The pH-dependent cationic or nonionic charge property and their varying levels of ethoxylation provides a wide range of properties, allowing for great formulation latitude.

Fatty amine ethoxylates can be great in detergents and they show excellent solvency, low foam properties, and chemical stability.
Fatty amine ethoxylates can also be used as emulsifying agents, wetting agents, dispersants, stabilizers, sanitizers and defoaming agents.
Their end use applications include agrochemical emulsifiers, personal care emulsifiers, industrial cleaners, metal cleaners, anti-stats in textiles, paper de-inking, and drilling products

Fatty Amine Ethoxylate finds application as dye levelling and wetting agents in textile formulations and detergents.
Fatty Amine Ethoxylate is also used as emulsifiers in pesticide formulations.

Fatty amine ethoxylates are nonionic surfactants used as wetting and dispersing agents, stabilizers, sanitizers and defoaming agents in various industries like textile, paper, drilling, chemical, paint, metal etc.
The fatty amine ethoxylates are used as emulsifiers and can also be employed in formulation of emulsifier blends.
Fatty amine ethoxylates play an important role as emulsifiers in agrochemical industries, cleaners in industrial processes especially in metal industry, oil field chemicals, fabric softeners, petroleum additives and for applications in textile and leather processing, paper de-inking, mining & drilling.
Fatty Amine Ethoxylates are used in detergents, textile compositions, oil field chemicals, and pesticide preparations, as wetting and colour levelling compounds.

Fatty Amine Ethoxylates like Tallow Amine Ethoxylate, Stearyl Amine Ethoxylate, Coco Amine Ethoxylate, Oleyl Amine Ethoxylate and Tallow Di Amine Ethoxylate having various ranges of applications in different industries like paint, automotive, agrochemical, Pharmaceutical, emulsion polymerization, and others.


HOW ARE FATTY AMINES ETHOXYLATES FORMULATED?
Production of fatty amines ethoxylate products takes place when the amines like amino acids, tallow amines, oleyl amine, coco amine, stearyl amines etc are made to react with ethylene oxide in presence of a catalyst in ethoxylation process.
Fatty amines are nitrogen derivatives of fatty acids, olefins, or alcohols prepared from natural sources, fats and oils, or petrochemical raw materials.
The commercially available fatty amines are prepared by either distillation of fatty acids or when fatty alcohols are reacted with ammonia or primary, secondary amines.



TYPES OF FATTY AMINE ETHOXYLATES:
Some of the popular forms of ethoxylated amines widely used in industrial processes include the tallow amines, coco amines, stearyl amines and oleyl amines.

The popular product used for soaps, leather dressings, candles, food, and lubricant applications in industries, tallow amine ethoxylate is derived from ethoxylation of tallow amine which is prepared from tallow, a hard fat usually extracted from fatty deposits of animals.
Tallow consists chiefly of glyceryl esters of oleic, palmitic, and stearic acids.

The oleyl amine ethoxylates are best used in textile applications.
With high affinity for surfaces these products are good for coating applications and as such are used for coating cloth, yarn etc.
They are good emulsifiers and are used in many cleaning and detergent formulations due to their antistatic behaviour and dispersing abilities.

In the similar way stearyl amine ethoxylates and coco amine ethoxylates are the two other widely used industrial surfactant products employed in different forms for various applications in diverse industries.



Tallow Amine Ethoxylate:
The composition of a tallow amine ethoxylate cream is usually a mixture of about 1:2 tallow: coconut oil and a small amount of tallow-amine.
The mixture is a surfactant that stabilizes the interaction of concentrated mineral acids with organic compounds.
Tallow Amine Ethoxylate has been used in cosmetics and personal care products for decades.


Properties & Applications of Tallow Amine Ethoxylate:
The composition of glyphosate-adjuvant cream includes a combination of a tallow-amine ethoxylate and coco-amine ethoxylate in a concentration of at least 25 wt%.
Tallow Amine Ethoxylate is particularly useful for treating rashes and it is derived from coco-oil.
Its efficacy is improved by ensuring that glyphosate is released at a higher rate in the skin after the application of the cream.

Tallow ethoxylate cream contains a non-ionic surfactant, TOMODOL 1-5, a linear C1-11 alkyl group (H23C11O5H) 5-OH.
In addition to TOMODOL, other non-ionic surfactants used in cosmetics creams are alkyl polyoxyethylene ethers and crop oil concentrates.
Other common ingredients are alkyl phosphates, fatty acid ethoxylates, and block copolymers.


Stearyl Amine Ethoxylate:
Stearyl Amine Ethoxylate is an ethoxylic acid, with a range of uses.
SAA is produced by Pharcos Speciality Ltd an exporter of Fatty Amine Ethoxylate.
The amine value of Stearyl Amine Ethoxylate is between 152-162.

Applications of Stearyl Amine Ethoxylate:
The production of fatty amine ethoxylates is a common process that produces several useful chemicals.
Fatty amines, which are derived from tallow and coco amine, are used as wetting agents and dyeing agents in textile processes.
Stearyl Amine Ethoxylate is a versatile surfactant with several uses.
In addition to textiles, Stearyl Amine Ethoxylate is used in cleaning and agrochemical products.
Stearyl Amine Ethoxylate is used to prevent corrosion, disperse emulsification, and reduce foaming.


EOs are nonionic surfactants that act as wetting agents, dispersing agents, stabilizers, and sanitisers. Their ability to disperse liquids is what makes them so useful in many applications.
In addition to textile processing, fatty amine ethoxylates are also used as petroleum additives and as fabric softeners.
This versatile ingredient is a key ingredient in many different products, including the detergent and cosmetics industries.

Coco Amine Ethoxylate:
Fatty amine ethoxylates are a class of non-ionic surfactants that exhibit exceptional surface wetting properties.
The unique properties of these ethoxylates make them an important component of most cleaning agents and other products.
As a result, they are used in a variety of commercial applications, including in the chemical industry and fabric enterprise.


Features & Applications of Coco Amine Ethoxylate:
Typically, they are liquids with different amounts of amines and different pH values.
Many of these products are custom-formulated to fit unique commercial packages.
Some are used in sanitizing agents, while others have a broad range of applications in household products and detergents.

EO is used to improve the performance of a quaternary formulation.
While coco amine is less effective, amidopropyl dimethylamines (C8-10) are more efficient coupling agents.
These surfactants are an excellent substitute for coco amine ethoxylate, especially in high-load formulations.
Further, unlike cocoamine, amidoalkylamines do not produce any undesirable side effects in the formulation.

Oleyl Amine Ethoxylate:
Oleyl Amine Ethoxylate is a type of nonionic surfactant that is widely used as a wetting and dispersing agent.
Oleyl Amine Ethoxylate has many applications in various industries, including textile processing, petroleum additives, and paper de-inking.
Oleyl Amine Ethoxylate is a non-flammable, water-soluble liquid.
Oleyl amine is a common chemical ingredient found in many household cleaners and cleaning products.

Oleyl Amine Ethoxylate is also called fatty amine ethoxylate.
Oleyl Amine Ethoxylate is a fatty hydrocarbon whose structure is similar to that of water.
Oleyl Amine Ethoxylate is one of the primary uses of fatty amine ethoxylates, which are sold as a variety of chemicals.
Oleyl Amine Ethoxylate is a nonionic surfactant and is used in textile and refinery industries.

Properties & Applications of Oleyl Amine Ethoxylate:
Oleyl Amine Ethoxylate is produced by a chemical reaction between cocoamine and ethylene oxide. This chemical is widely used in paint and coating applications and is a key ingredient in cosmetic waxes.
Oleyl amine ethoxylate developed by Pharcos Speciality an exporter of fatty amine Ethoxylates adheres to defined industry norms and protocols.
These qualities make it an excellent cleaning seller.

Oleyl Amine Ethoxylate has a range of ethoxylation degrees.
Oleyl Amine Ethoxylate is somewhat dispersible at room temperature.
Oleyl Amine Ethoxylate forms a clear solution when mixed with water.
The recommended working temperature is 50-60degC.

Tallow Di Amine Ethoxylate:
The chemical substance Tallow Di Amine Ethoxylate is a petroleum derivative.
Tallow Di Amine Ethoxylate can be found in many pharmaceutical products, including shampoos, candles, and soaps.

Applications & Properties of Tallow Di Amine Ethoxylate:
As a exporter of Fatty amine Ethoxylates, these are widely used in cosmetics and sanitary products. Their surface activity enables them to improve grip and hydrophobicity.
Furthermore, they are used in the manufacture of textile auxiliaries and mineral oils.
Tallow amine ethoxylates can be used alone or in combination with other types of surfactants.
This chemical additive is indifferent to hard water and is compatible with most cationic and nonionic surfactants.

Fatty amine ethoxylates are produced by reacting the fatty amine with ethylene oxide.
The resulting chemical is dihydric alcohol with a hydrophobic tail.
Fatty amine ethoxylates are also hydrophilic and can be quaternized.
Fatty amine ethoxylates are highly effective in detergents and other formulations requiring nonionic surfactants.
Fatty amine ethoxylates are highly miscible and stable in acidic and alkaline solutions.



PRODUCTION AND REACTIONS OF FATTY AMINE ETHOXYLATE:
Fatty Amine Ethoxylate is commonly prepared from fatty acids; which are themselves obtained from natural sources, typically seed-oils.
The overall reaction is sometimes referred to as the Nitrile Process and begins with a reaction between the fatty acid and ammonia at high temperature (>250 °C) and in the presence of a metal oxide catalyst (e.g., alumina or zinc oxide) to give the fatty nitrile.

RCOOH + NH3 → RC≡N + 2 H2O
The fatty amine is obtained from this by hydrogenation with any of a number of reagents, including Raney nickel or cobalt, and copper chromite catalysts.
When conducted in the presence of excess ammonia the hydrogenation affords the primary amines.

RCN + 2 H2 → RCH2NH2
In the absence of ammonia, secondary and tertiary amines are produced.

2 RCN + 4 H2 → (RCH2)2NH + NH3
3 RCN + 6 H2 → (RCH2)3N + 2 NH3
Fatty secondary and tertiary amines:
Alternatively, secondary and tertiary fatty amines can be generated by the reaction of fatty alcohols and fatty alkyl bromides with (di)alkylamines.
For example 1-bromododecane reacts with dimethyl amine:

RBr + HNMe2 → RNMe2 + HBr
By reaction with tertiary amines, long-chain alkyl bromides give quaternary ammonium salts, which are used as phase transfer catalysts.

Secondary and tertiary amines may also be produced by the Leuckart reaction.
This reaction effects N-methylation using formaldehyde with formic acid as the reductant.
These tertiary amines are precursors to quaternary ammonium salts used for a variety of applications.


APPLICATIONS AND DERIVATIVES OF FATTY AMINE ETHOXYLATE:
The main application of Fatty Amine Ethoxylate is for the production of the corresponding quaternary ammonium salts, which is used as fabric softeners and hair conditioners (e.g. Behentrimonium chloride).
Fatty Amine Ethoxylate is also used in froth flotation, for the beneficiation of various ores.
The amines bind to the surfaces of certain minerals allowing them to be readily separated from those lacking the bound amine.
Fatty Amine Ethoxylate is also additives in the production of asphalt.






BENEFITS OF FATTY AMINE ETHOXYLATE:
Fatty Amine Ethoxylate is Insensitive to water hardness
Fatty Amine Ethoxylate Can be combined with all types at nonionic and cationic surfactants
Fatty Amine Ethoxylate is Resistant to most chemicals at typical concentrations used.




SAFETY INFORMATION ABOUT FATTY AMINE ETHOXYLATE:

First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.





FATTY AMINES 
SYNONYMS Ammonium Iron(III) Citrate; Ammonium ferric citrate; Iron ammonium citrate; 2-Hydroxy-1,2,3-Propanetricarboxylic Acid, Ammonium Iron (3+) Salt; Prothoate+; Iron (II) ammonium citrate; Cas no: 1185-57-5
FB 400 SODIUM PERCARBONATE
FB 400 Sodium Percarbonate is an additional compound of sodium carbonate and hydrogen peroxide.
FB 400 Sodium Percarbonate is a colorless, crystalline, hygroscopic and water-soluble solid.
FB 400 Sodium Percarbonate provides a stable source of alkaline hydrogen peroxide which is environmentally friendly and easy to use.


CAS Number: 15630-89-4
EC Number: 239-707-6
MDL number: MFCD00043204
Molecular Formula: 2Na2CO3 • 3H2O2


FB 400 Sodium Percarbonate, or sodium carbonate peroxide is a chemical substance with formula Na2H3CO6.
FB 400 Sodium Percarbonate is an adduct of sodium carbonate ("soda ash" or "washing soda") and hydrogen peroxide (that is, a perhydrate) whose formula is more properly written as 2 Na2CO3 · 3 H2O2.


FB 400 Sodium Percarbonate is an additional compound of sodium carbonate and hydrogen peroxide.
FB 400 Sodium Percarbonate is sometimes abbreviated as SPC.
FB 400 Sodium Percarbonate contains 32.5% by weight of hydrogen peroxide.


FB 400 Sodium Percarbonate provides a stable source of alkaline hydrogen peroxide that is ecologically responsible and easy to use.
FB 400 Sodium Percarbonate is a multifunctional reagent for preparing optically active 4-hydroxy-2-isoxazolines.
FB 400 Sodium Percarbonate is also known as sodium carbonate peroxyhydrate or oxygen bleach.


FB 400 Sodium Percarbonate comes in the form of granulated, coated, white powder.
FB 400 Sodium Percarbonate is also a colorless, crystalline, hygroscopic, water-soluble solid with an active available oxygen content (13%), corresponding to 27.5% hydrogen peroxide.


FB 400 Sodium Percarbonate contains carbonate anion.
FB 400 Sodium Percarbonate does not contain phosphorus or nitrogen.
When dissolved in water, FB 400 Sodium Percarbonate produces a mixture of hydrogen peroxide (which eventually decomposes into water and oxygen) and sodium carbonate ("soda ash").


FB 400 Sodium Percarbonate is a natural oxygen bleach and an ingredient in many home cleaning and laundry products.
FB 400 Sodium Percarbonate appears as a colorless, crystalline solid. FB 400 Sodium Percarbonate is denser than water.
FB 400 Sodium Percarbonate may combust in contact with organic materials.


FB 400 Sodium Percarbonate is a strong oxidizing agent that may combust on contact with organic substances.
FB 400 Sodium Percarbonate is decomposed by water.
FB 400 Sodium Percarbonate is an addition product of hydrogen peroxide and sodium carbonate.


FB 400 Sodium Percarbonate dissociates into hydrogen peroxide, carbonate, and sodium ions on contact with body fluids (all found naturally in the human body).
FB 400 Sodium Percarbonate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 tonnes per annum.
FB 400 Sodium Percarbonate is a white granular product that provides a stable source of alkaline hydrogen peroxide which is environmentally friendly and easy to use.


FB 400 Sodium Percarbonate has an active available oxygen content which is equivalent to 27.5% H2O2.
FB 400 Sodium Percarbonate offers many of the same functional benefits as liquid hydrogen peroxide.
As an oxidant, FB 400 Sodium Percarbonate provides powerful cleaning, bleaching, stain removal and deodorizing capabilities.
These attributes make FB 400 Sodium Percarbonate a product that is environmentally benign because its products of decomposition are water, oxygen and soda ash.



USES and APPLICATIONS of FB 400 SODIUM PERCARBONATE:
FB 400 Sodium Percarbonate is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
FB 400 Sodium Percarbonate is used in the following products: washing & cleaning products, cosmetics and personal care products, biocides (e.g. disinfectants, pest control products), water softeners and water treatment chemicals.


FB 400 Sodium Percarbonate is used in the following products: washing & cleaning products, pH regulators and water treatment products, water treatment chemicals, cosmetics and personal care products, biocides (e.g. disinfectants, pest control products), metal surface treatment products, non-metal-surface treatment products, metal working fluids, textile treatment products and dyes and water softeners.


Other release to the environment of FB 400 Sodium Percarbonate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).
FB 400 Sodium Percarbonate is used in the following areas: agriculture, forestry and fishing.


FB 400 Sodium Percarbonate is used for the manufacture of: textile, leather or fur.
Other release to the environment of FB 400 Sodium Percarbonate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as reactive substance.


FB 400 Sodium Percarbonate is used in the following products: biocides (e.g. disinfectants, pest control products), metal surface treatment products, non-metal-surface treatment products, pH regulators and water treatment products, metal working fluids, textile treatment products and dyes, washing & cleaning products, water softeners, water treatment chemicals and cosmetics and personal care products.


FB 400 Sodium Percarbonate is used in the following products: washing & cleaning products, biocides (e.g. disinfectants, pest control products), metal surface treatment products, non-metal-surface treatment products, pH regulators and water treatment products, metal working fluids, textile treatment products and dyes, water softeners, water treatment chemicals and cosmetics and personal care products.


FB 400 Sodium Percarbonate is used in the following areas: formulation of mixtures and/or re-packaging and scientific research and development.
Release to the environment of FB 400 Sodium Percarbonate can occur from industrial use: formulation of mixtures, as processing aid and of substances in closed systems with minimal release.


FB 400 Sodium Percarbonate is used for the manufacture of: plastic products.
Release to the environment of FB 400 Sodium Percarbonate can occur from industrial use: as processing aid, of substances in closed systems with minimal release and formulation of mixtures.


Release to the environment of FB 400 Sodium Percarbonate can occur from industrial use: manufacturing of the substance.
End Use of FB 400 Sodium Percarbonate: Algaecide, Bleach, Carpet Cleaners, Cosmetics, Denture Cleaner, Dishwash Detergents, Pulp & Paper, Scouring Powder, Stain Removers, Swimming Pool, Teeth Whitening, Textile Bleaching, Toothpaste, Wood Deck Bleaching.


FB 400 Sodium Percarbonate has an active available oxygen content that is equivalent to 27.5% H2O2.
FB 400 Sodium Percarbonate is used in some eco-friendly bleaches and other cleaning products
FB 400 Sodium Percarbonate is used to make other chemicals.


FB 400 Sodium Percarbonate has a strong bleaching effect and thus removes stains and discolourations reliably.
FB 400 Sodium Percarbonate is used for conventional use, add one tablespoon (approx. 20 g - 25 g) of bleach to teh washing cycle.
FB 400 Sodium Percarbonate is used for more stubborn stains, mix the bleach with a little water and apply directly to the stain.


FB 400 Sodium Percarbonate is added to the laundry cycle as usual.
FB 400 Sodium Percarbonate is used to make other chemicals.
FB 400 Sodium Percarbonate is used mainly as a bleaching agent in household laundry detergents and additives and dishwashing machine products.


FB 400 Sodium Percarbonate is also used in other consumer cleaning products, dental care products, and for the preservation of raw milk.
FB 400 Sodium Percarbonate is used as an algaecide and fungicide for ornamentals, turf grasses, landscapes, commercial greenhouses, garden centers, nurseries, and storage areas.


FB 400 Sodium Percarbonate is permitted for use as an inert ingredient in non-food pesticide products.
FB 400 Sodium Percarbonate can be used in organic synthesis as a convenient source of anhydrous H2O2, in particular in solvents that cannot dissolve the carbonate but can leach the H2O2 out of it.


A method for generating trifluoroperacetic acid in situ for use in Baeyer–Villiger oxidations from sodium percarbonate and trifluoroacetic anhydride has been reported.
FB 400 Sodium Percarbonate provides a convenient and cheap approach to this reagent without the need to obtain highly concentrated hydrogen peroxide.
FB 400 Sodium Percarbonate is applied in the formulation of laundary products and many other detergents.


FB 400 Sodium Percarbonate can provide effective cleaning, bleaching, stain removal capabilities and is environmentally compatible.
FB 400 Sodium Percarbonate is broadly used in the formulation of oxygenated powder laubdary products.
FB 400 Sodium Percarbonate has major applications in heavy duty laundary detergents, all-fabric, paper and pulp, textile and dyeing bleaches, Vat Dye Oxidation and Carpet Cleaners.


FB 400 Sodium Percarbonate is also used in the preparation of disinfectants and used as oxygen generator in fish raising industry and for medical emergency.
FB 400 Sodium Percarbonate is used heavy duty laundary detergents, all-fabric, paper and pulp, textile and dyeing bleaches, Vat Dye Oxidation and Carpet Cleaner
FB 400 Sodium Percarbonate is used in some eco-friendly cleaning products and as a laboratory source of anhydrous hydrogen peroxide.


Applications of FB 400 Sodium Percarbonate in the textile, laboratory and water treatment industries.
FB 400 Sodium Percarbonate has a wide range of applications including use in heavy-duty laundry detergents, allfabric bleaches, wood deck bleaches, textile bleaches and carpet cleaners.


FB 400 Sodium Percarbonate has no registered food uses.
FB 400 Sodium Percarbonate is used in a number of general cleaning products in the institutional and industrial marketplace.
FB 400 Sodium Percarbonate also has used in personal care formulations, denture cleaners and certain food bleaching applications.


FB 400 Sodium Percarbonate has a wide range of applications including use in heavy duty laundry detergents, all fabric bleaches, wood deck bleaches, textile bleaches and carpet cleaners.
FB 400 Sodium Percarbonate is used in a number of general cleaning products in the Institutional and Industrial marketplace.


FB 400 Sodium Percarbonate also has use in personal care formulations, denture cleaners, and certain food bleaching applications.
FB 400 Sodium Percarbonate is used in the textile industry as bleaching lotion, reduction chromogenic agent, can also be alone as a sanitizer antistaling agent, in addition to flavor agent, milk and so on.



FEATURES OF FB 400 SODIUM PERCARBONATE:
*suitable for coloured and white garments
*removes stains and discolourations
*eliminates and prevents the formation of a gray film
*very good disinfecting effect
*particularly effective and efficient



FEATURES AND ADVANTAGES OF FB 400 SODIUM PERCARBONATE:
*Perfect bleaching agent
*Disinfecting effect
*May be used with temperatures as low as 30 °C
*Efficient



PHYSICAL and CHEMICAL PROPERTIES of FB 400 SODIUM PERCARBONATE:
Physical state: solid
Color: white
Odor: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 140 g/l at 20 °C
Partition coefficient: n-octanol/water:
Bioaccumulation is not expected.
Vapor pressure: No data available
Density: No data available
Relative density: 2,01 at 20,4 °C
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Other safety information: No data available

CAS No.: 15630-89-4
UN No.: 3378
Molecular Formula: CH2O3.3/2H2O2.2Na
InChIKeys: InChIKey=ZWGNLOMJTJIUPZ-UHFFFAOYSA-N
Molecular Weight: 314.02100
Exact Mass: 313.94500
EC Number: 239-707-6
PSA: 247.76000
XLogP3: -4.84180
Appearance: Free flowing white granular powder
Density: 0.90 g/cm3 (20ºC)
Melting Point: No melting point; decomposes at >50 °C
Boiling Point: 333.6ºC at 760 mmHg
Flash Point: 169.8ºC
Water Solubility: Solubility in water, g/100ml at 20 °C: 14 (good)
Vapor Pressure: 2.58E-05mmHg at 25°C
Air and Water Reactions: Soluble in water.
Reactive Group: Salts, Basic
Appearance: White, good fluidity
Active Oxygen(O): ≥ 13.5%
Iron(Fe)(%): ≤ 0.0015 %

Moisture(%): ≤2.0%
Bulk Density,g/l: 700-1100
PH value(3%water solution,20℃): ≥10~~11
Molecular Weight: 314.02 g/mol
Hydrogen Bond Donor Count: 6
Hydrogen Bond Acceptor Count: 12
Rotatable Bond Count: 0
Exact Mass: 313.94500275 g/mol
Monoisotopic Mass: 313.94500275 g/mol
Topological Polar Surface Area: 248Ų
Heavy Atom Count: 18
Formal Charge: 0
Complexity: 18.8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 9
Compound Is Canonicalized: Yes



FIRST AID MEASURES of FB 400 SODIUM PERCARBONATE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of FB 400 SODIUM PERCARBONATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of FB 400 SODIUM PERCARBONATE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of FB 400 SODIUM PERCARBONATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of FB 400 SODIUM PERCARBONATE:
-Precautions for safe handling:
*Hygiene measures:
Change contaminated clothing.
Preventive skin protection recommended.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Away from combustible materials and sources of ignition and heat.
Do not store near combustible materials.



STABILITY and REACTIVITY of FB 400 SODIUM PERCARBONATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available



SYNONYMS:
Sodium Percarbonate
Sodium Carbonate Peroxide, PCS
Carbonic acid disodium salt, compd. with hydrogen peroxide(2:3)
Disodium carbonate, hydrogen peroxide (2:3)
Carbonic acid sodium salt (1:2), compd. with hydrogen peroxide (H2O2) (2:3)
Carbonic acid disodium salt, compd. with hydrogen peroxide (H2O2) (2:3)
Carbonic acid, disodium salt, compd. with hydrogen peroxide (2:3)
Hydrogen peroxide (H2O2), compd. with disodium carbonate (3:2)
Hydrogen peroxide, compd. with disodium carbonate (3:2)
BIOXY S
BIOXY S NEW
Disodium carbonate compd. with hydrogen peroxide (Na2CO3.1.5 H2O2)
Disodium carbonate sesquiperoxide
Disodium carbonate-hydrogen peroxide compd. (2:3)
ECOX-C
FB 100
FB 100 (percarbonate)
FB 400
FB Sodium Percarbonate
IPC 14FR
KCPZ-S
OxiClean
Oxyper
Oxyper FB 400C
Oxyper Grade FB 400C
Oxyper S 131
Oxyper S 142
Oxyper SHC
PC-F
PC-NB
PC-P
PC-P (percarbonate)
PC-PHAS
PC-W
Percarbonate Q 30
Perdox
Peroxy sodium carbonate
Phycomycin SCP
Provos S
Provox C
SPC-D
SPC-D (peroxide)
SPC-ED
SPC-HGD
SPC-Q 1
SPC-Q 2
SPC-Q 3
SPC-Q 4
SPC-Z
SPCC
SPCC 8J
SPD-ED, Sodium carbonate peroxide, Sodium carbonate sesquiperoxide (2Na2CO3.3H2O2)
Sodium percarbonate, Sodium percarbonate (Na2CO3.1.5H2O2)
Carbonic acid disodium salt, compd. with hydrogen peroxide (2:3)
disodium carbonate, compound with hydrogen peroxide (2:3)
Carbonic acid, disodium salt, compound with hydrogen peroxide (H2O2) (2:3)
CARBONIC ACID DISODIUM SALT
COMPOUND, WITH HYDROGEN PEROXIDE, SODIUM CARBONATE PEROXYHYDRATE
Disodium carbonate compd. with hydrogen peroxide (2:3)
disodium carbonate-hydrogen peroxide (2:3)
Sodium carbonate peroxohydrate, Sodium percarbonate
Disodium peroxidicarbonate
Sodium peroxydicarbonate
Dinatriumcarbonat
Verbindung mit Hydrogenperoxid (2:3)
Natriumperoxocarbonat
Natriumcarbonatperoxyhydrat, Natriumpercarbonat
sodium percarbonate
SODIUM PERCARBONATE POWDER
SODIUM PERCARBONATE GRANULAR
OXYPER SCS
Sodium carbonate peroxide
Disodium carbonate, compound with hydrogen peroxide (2:3)
Sodium percarbonate
15630-89-4
Oxyper
Sodium carbonate peroxyhydrate
Sodium carbonate peroxide
Perdox
FB Sodium percarbonate
Peroxy sodium carbonate
Z7G82NV92P
EINECS 239-707-6
tetrasodium;hydrogen peroxide;dicarbonate
UNII-Z7G82NV92P
Disodium carbonate, hydrogen peroxide (2:3)
PEROXODICARBONATE DISODIUM
HSDB 8161
Disodium carbonate, compound with hydrogen peroxide (2:3)
EC 239-707-6
SODIUM PERCARBONATE (MART.)
SODIUM PERCARBONATE [MART.]
ECOX-C
Sodium percarbonate, CP
SODIUM PERCARBONATES
Sodium Percarbonate (Coated)
Sodium Percarbonate (Uncoated)
DTXSID3029736
CH2O3.3/2H2O2.2Na
NA2467
SODIUM PERCARBONATE [WHO-DD]
C-H2-O3.3/2H2-O2.2Na
DISODIUM CARBONATE SESQUIPEROXIDE
SODIUM CARBONATE PEROXIDE [INCI]
USEPA/OPP Pesticide Code: 128860
LS-51985
PEROXODICARBONATE DISODIUM [WHO-DD]
disodium carbonate hydrogen peroxide (2:3)
FT-0688134
Sodium percarbonate, avail. H2O2 20-30 %
SODIUM PERCARBONATE (NA2CO3.1.5H2O2)
Q420070
SODIUM CARBONATE SESQUIPEROXIDE (2NA2CO3.3H2O2)
DISODIUM CARBONATE COMPOUND WITH HYDROGEN PEROXIDE (2:3)
HYDROGEN PEROXIDE, COMPOUND WITH DISODIUM CARBONATE (3:2)
CARBONIC ACID DISODIUM SALT, COMPOUND WITH HYDROGEN PEROXIDE (2:3)
HYDROGEN PEROXIDE (H2O2), COMPOUND WITH DISODIUM CARBONATE (3:2)
DISODIUM CARBONATE COMPOUND WITH HYDROGEN PEROXIDE (NA2CO3.1.5 H2O2)
Carbonic acid, disodium salt, compd. with hydrogen peroxide (2:3)
Disodium carbonate, hydrogen peroxide (2:3)
FB Sodium Percarbonate
Oxyper
Perdox
Peroxy sodium carbonate
Sodium carbonate peroxide
Sodium carbonate peroxyhydrate
Carbonic acid sodium salt (1:2), compd. with hydrogen peroxide (H2O2) (2:3)
Disodium carbonate, compound with hydrogen peroxide (2:3)
Carbonic acid disodium salt, compound with hydrogen peroxide (2:3)
Disodium carbonate sesquiperoxide
Ecox-C
Hydrogen peroxide, compound with disodium carbonate (3:2)
Sodium percarbonates
Percarbonate
PCS
Hydrogen peroxide sodium carbonate adduct
UN3378
SPC-Q 1, SPC-Q 4
SPC-Q 2, Oxyper, ECOX-C
FB Sodium Percarbonate
Perdox
Carbonic acid disodium salt, compounds, compound with hydrogen peroxide (2:3)
SPC-Q 3
Natriumpercarbonat, nicht gecoated
disodium carbonate, compound with hydrogen peroxide (2:3)
Hydrogen peroxide sodium carbonate adduct
sodium carbonate—hydrogen peroxide (2/3)
Sodium carbonate peroxide
sodium carbonate sesquiperhydrate
PCS
SPC, solid hydrogen peroxide
Sodium carbonate hydrogen peroxide
sodium carbonate peroxyhydrate




FENOKSIETANOL& BRONOPOL & PARABEN
Su ve yağ fazını birarada içeren emülsiyonlarda her iki fazıda korur. El kremleri, Vücut sütleri, Biryantin (%0.3-1.3)
FENOKSİETANOL & DBGN & CIT/ MIT
Her türlü kozmetik, jel ve kremlerde kullanılan geniş spektrumlu koruyucu. Cilt bakımı, şampuan, Kremler, Islak mendil, Deterjanlar (%0.05-0.2)
FENOKSİETANOL VE PARABEN KARIŞIMI
Kozmetik ve kişisel bakım ürünlerinde kullanılan geniş spektrumlu antimikrobiyel koruyucu. Yüksek sıcaklık pH:3-8 arasında etkilidir. Kozmetik ürünlerinde (%0.3-1)
FENTIN HYDROXIDE
Fentin hydroxide is an organotin compound with formula Sn(C6H5)3OH, used as a fungicide for potatoes, sugar beets, and pecans.
Fentin hydroxide has an acid dissociation constant of pKa = 5.20, and is expected to have very low mobility within soil.
Fentin hydroxide has low solubility in water and binds strongly to soil.

CAS Number: 76-87-9
EC Number: 200-990-6
Chemical formula: C18H16OSn
Molar mass: 367.035 g·mol−1

Synonyms: Triphenyltin hydroxide, FENTIN HYDROXIDE, Triphenylstannanol, Fentin, 76-87-9, Tptoh, Vancide ks, Hydroxytriphenyltin, Hydroxytriphenylstannane, Erithane, Fenolovo, Tenhide, Stannane, hydroxytriphenyl-, Duter extra, Triphenyltin oxide, Dowco 186, Du-Ter, Suzu H, Haitin, Stannol, triphenyl-, Fintin hydroxid, TPTH, Fintin hydroxyde, Fintin idrossido, Phenostat-H, Sunitron H, Fintine hydroxyde, Tin, hydroxytriphenyl-, Du-Ter W-50, Trifenyl-tinhydroxyde, Triphenyl-zinnhydroxid, Flo-Tin 4L, Triphenylstannium hydroxide, NCI-C00260, Hydroxyde de triphenyl-etain, Idrossido di stagno trifenile, ENT 28009, Trifenylstanniumhydroxid, K 19, OMS 1017, NSC 113243, K19, Tpth Technical, Du-Ter Fungicide, Triple Tin 4l, Vito Spot Fungicide, Flo Tin 4l, Du-Tur Flowable-30, Caswell No. 896E, Duter, Fentin hydroxide, Ida, Imc Flo-Tin 4L, Fintin hydroxid, Fintin hydroxyde, Fintine hydroxide, Triphenyltin(IV) hydroxide, Du-Ter PB-47 Fungicide, Fintin idrossido, Fintine hydroxide, Fintine hydroxyde, CCRIS 612, Triphenyltinhydroxide, Trifenyl-tinhydroxyde, Brestan H 47.5 WP fungicide, Triphenyl-zinnhydroxid, Trifenylstanniumhydroxid, Du-Ter Fungicide Wettable Powder, HSDB 1784, K 19 (VAN), EINECS 200-990-6, Hydroxyde de triphenyl-etain, EPA Pesticide Chemical Code 083601, Wesley Technical Triphenyltin Hydroxide, C18H16OSn, BRN 4139186, Haitin WP 20 (fentin hydroxide 20%), Haitin WP 60 (fentin hydroxide 60%), Idrossido di stagno trifenile, Super Tin 4L Gardian Flowable Fungicide, Farmatin, Ashlade flotin, AI3-28009, Fentin-hydroxide, Super-tin, Sn(OH)Ph3, fentin hydroxide (ISO), hydroxy(triphenyl)stannane, DSSTox_CID_1409, [Sn(OH)Ph3], triphenylstannylium hydroxide, DSSTox_RID_76145, WLN: Q-SN-R&R&R, DSSTox_GSID_21409, SCHEMBL70052, triphenylstannanylium;hydroxide, DTXSID1021409, CHEBI:30473, Tox21_300754, MFCD00013928, NSC113243, AKOS015960675, ZINC169876287, NSC-113243, CAS-76-87-9, NCGC00163909-01, NCGC00163909-02, NCGC00163909-03, NCGC00163909-04, NCGC00254659-01, O595, C18729, Fentin hydroxide, PESTANAL(R), analytical standard, Q7843285

Fentin hydroxide is an organotin compound with formula Sn(C6H5)3OH.
Fentin hydroxide is used as a fungicide for potatoes, sugar beets, and pecans.

Fentin hydroxide was first registered for use as a pesticide in the United States in 1971.
Fentin hydroxide is a non-systemic foliar fungicide used to control early and late blight on potatoes, leaf spot on sugar beets, and select fungal diseases on pecans.

Fentin hydroxide also exhibits anti-feeding properties for some surface-feeding insects (e.g., Colorado potato beetle).
Fentin hydroxide is a restricted use pesticide (RUP) and is only registered for use on these three crops.

There are no residential, public health, or other non-food uses of Fentin hydroxide.
In 2017, over 200,000 pounds of this active ingredient were sold in Minnesota.

Fentin hydroxide is an odorless white powder.
Fentin hydroxide is stable at room temperature.

Fentin hydroxide's melting point 121-123°C.
Fentin hydroxide moderately soluble in most organic solvents.

Fentin hydroxide is insoluble in water.
Fentin hydroxide is non corrosive.
Fentin hydroxide is used as a fungicide.

Triphentin hydroxide is an organotin compound that is triphenylstannane in which the hydrogen attached to tin is replaced by a hydroxy group.
Fentin hydroxide used to control a variety of infections including blight on potatoes, leaf spot on sugar beet and alternaria blight on carrots.

Fentin hydroxide has a role as an acaricide and an antifungal agrochemical.
Fentin hydroxide is an organotin compound and a member of hydroxides.
Fentin hydroxide derives from a triphenylstannane.

Fentin hydroxide inhibits oxidative phosphorylation (respiration) and fungal growth.
Fentin hydroxide is a Fungicide Resistance Action Committee (FRAC) code 30 fungicide which inhibits adenosine triphosphate (ATP) synthase preventing the production of ATP by cell mitochondria.

Fentin hydroxide is an organotin compound with formula Sn(C6H5)3OH.
Fentin hydroxide is used as a fungicide for potatoes, sugar beets, and pecans.
Fentin hydroxide was first registered for use as a pesticide in the United States in 1971.

Fentin hydroxide has low solubility in water and binds strongly to soil.
Therefore, Fentin hydroxide is not expected to leach to groundwater; however, Fentin hydroxide may reach surface water through spray drift and surface run-off.

To protect nontarget organisms, product labels include application setbacks from surface waters such as rivers, streams, ponds, and lakes of 100 feet for ground boom sprayers and 300 feet for aerial applications.
Fentin hydroxide is semi-volatile from dry surfaces but non-volatile from water.
The aerobic soil half-life of Fentin hydroxide is greater than 1,114 days.

Fentin hydroxide is an organotin that was formerly used as a fungicide.
Fentin hydroxide is soluble in water up to 1.2 mg/L at 20 C and has a density of 1.54 g/mL.

Fentin hydroxide has an acid dissociation constant of pKa = 5.20.
Fentin hydroxide is expected to have very low mobility within soil.

If discharged to water the compound may convert to triphenyltin oxides, hydroxides or carbonates based on the acid dissociation constant.
The anions will not adsorb to suspended solids but the cations will.

Photolysis of the triphenyltin cation is expected to be a major fate process in water.
Bioaccumulation in organisms is expected to be high.

The does not currently test for Fentin hydroxide in groundwater and surface water samples.
Analysis for this chemical cannot be incorporated into the existing procedures used by the laboratory and would require additional analytical methods or laboratory equipment.

Monitoring conducted in the state by the US Geological Survey (USGS) between 2012 and 2019 has not detected Fentin hydroxide in groundwater or surface water samples.
Fentin hydroxide has been detected in surface water samples from other upper Midwest states including Iowa and North Dakota.
The overall detection frequency in surface waters in the US has been low, less than <1% of surface water samples.

Fentin hydroxide is very highly toxic to fish and aquatic invertebrates on an acute exposure basis.
The Environmental Protection Agency (EPA) Office of Pesticide Programs aquatic life benchmarks are 3550 and 65 ppt for acute and chronic exposure, respectively.

EPA categorizes Fentin hydroxide as moderately toxic to birds and mammals from acute oral exposure (mallard duck LD50 = 378 mg ai/kg; Norway rat LD50 = 156 mg ai/kg).
Some vascular plants are also sensitive to high rates of this fungicide.
Fentin hydroxide is considered practically nontoxic to bees on an acute contact basis.

Fentin hydroxide is a chemical compound that reacts with an enzyme called glutathione reductase.
Fentin hydroxide has been shown to have genotoxic effects in the galleria mellonella, which is a type of insect commonly used as a model organism for studies on genetic toxicity.

Fentin hydroxide has also been shown to be toxic to mammalian cells.
The mechanism of this reaction and the inhibition of glutathione reductase by Fentin hydroxide is not fully understood and may involve reactive oxygen species production.

Fentin hydroxide can react with other molecules in order to form new compounds, such as methoxyFentin hydroxide, which has been shown to be an effective anti-cancer compound.
Fentin hydroxide can also react with fluoroacetic acid to form triphenyltin fluoride, which has been shown to be an effective herbicide.

Uses of Fentin hydroxide:
Fentin hydroxide is used in insecticides, non-systemic fungicides (potatoes, sugar beets, nuts, rice, beans, and vegetables), and antifouling paints.
Antifeeding compounds for insect pest control; nonsytemic fungicide.
Fentin hydroxide is used as fungicide.

Fentin hydroxide is used for early and late blight on potatoes, leaf spot on sugar beets, peanuts, scab, and several other diseases on pecans.
Fungal diseases on rice, beans, garlic, onion, pepper, tomato.

Exhibits antifeeding properties for surface-feeding insects.
Fentin hydroxide is used as agricultural fungicides in crop protection.

They are employed to control potato, celery, sugar beet, coffee, and rice against fungal disease.
Fentin hydroxide is also used as a biocide in antifouling paints.

Fentin hydroxide is a non-systemic foliar fungicide used to control early and late blight on potatoes; leaf spot on sugar beets; and scab, brown leaf spot and other diseases on pecans.
Fentin hydroxide is only registered for use on these three crops.

There are no residential, public health or other non-food uses of Fentin hydroxide.
Fentin hydroxide comes in liquid and wettable powder (in water soluble packaging) formulations, and its use is restricted to certified applicators.

Fentin hydroxide is applied by ground equipment, chemigation, airblast spray, and aircraft.
Fentin hydroxide labels require mechanical transfer for liquids, and a closed mixing/loading system for aerial applications.

Handlers are required to wear coveralls, waterproof gloves, chemical resistant footwear, protective eyewear, chemical resistant headgear for overhead exposure, and chemical resistant apron when cleaning equipment, mixing, or 2 loading.
These protective measures may be reduced or modified as specified by the Worker Protection Standard (WPS) when closed systems or enclosed cabs are used.

Industry Uses:
Other (specify)

Consumer Uses:
Other (specify)

Manufacturing of Fentin hydroxide:
Production from triphenyltin chloride by hydrolysis with aqueous sodium hydroxide.

General Manufacturing Information:

Industry Processing Sectors:
Pesticide, fertilizer, and other agricultural chemical manufacturing

Action Mode of Fentin hydroxide:
Fentin hydroxide inhibits oxidative phosphorylation (respiration) and fungal growth.
Fentin hydroxide is a Fungicide Resistance Action Committee (FRAC) code 30 fungicide which inhibits adenosine triphosphate (ATP) synthase preventing the production of ATP by cell mitochondria.

Structure of Fentin hydroxide:
While Fentin hydroxide is often depicted as a monomer, Fentin hydroxide crystallizes as a polymer with a bridging hydroxide groups.
The Sn-O distances are 2.18 and 2.250 Å.
Many organotin compounds engage in similar aggregation equilibria.

Analytic Laboratory Methods of Fentin hydroxide:
Five laboratories collaboratively studied 2 procedures for the quantitative determination of triphenyltin compounds in technical material & in pesticide formulations.
Both procedures included an extraction step & a potentiometric titration, but differed in how the by products were removed.

The 1st was based on cleanup with sodium tartrate & in the 2nd, alkaline alumina was used for purification.
The reproducibility & the repeatability were better with the alumina method than with the tartrate method.

The average systematic difference between the 2 methods was -2.3%.
The method based on alkaline alumina cleanup was adopted as an interim cipac method.

Determination of triphenyltin compounds & tricyclohexyltin hydroxide by gas chromatography of their derivatives.
A gas-liquid chromatographic method is reported for the determination of triphenyltin derivatives & tricyclohexyltin hydroxide after their conversion (by way of grignard reaction catalyzed by copper chloride) to tetraphenyltin & tricyclohexylphenyltin.

The recovery of tetraphenyltin & tricyclohexylphenyltin was satisfactory in the range of 50 to 3000 ug. different columns were tested using flame-ionization detection.
For both derivatives, the response was linear from 0.05 to 3.00 ug. results of thermal analysis, ir spectroscopy, & mass spectrometry are reported.

Experimental Properties of Fentin hydroxide:
Thermally decomp to phenyltin, phenyltin oxide and water.
Dehydration to oxide occurs on heating above 45 °C.
Triorganotin hydroxides behave not as alcohols, but more like inorganic bases, although strong bases remove the proton in certain triorganotin hydroxides since tin is amphoteric.

Pharmacology and Biochemistry of Fentin hydroxide:

Absorption, Distribution and Excretion:
Several studies have shown that Fentin hydroxide orally admin to rats is eliminated mainly via the feces, with smaller amounts in the urine.

Metabolites found in feces included di- & monophenyltin as well as a significant portion of non-extractable bound residues (the sulfate conjugates of hydroquinone, catechol, & phenol).
In feces, the major substance present was unchanged parent compound.

Seven days after oral admin to rats, Fentin hydroxide residues (approx 3% of the admin dose) were distributed mainly in the kidneys, followed by liver, brain, & heart.

Handling and Storage of Fentin hydroxide:

Precautions for safe handling:

Advice on safe handling:
Work under hood.
Do not inhale substance/mixture.

Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.

Conditions for safe storage, including any incompatibilities:

Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.

Storage class:
Storage class (TRGS 510): 6.1A: Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

Stability and Reactivity of Fentin hydroxide:

Reactivity:

The following applies in general to flammable organic substances and mixtures:
In correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Chemical stability:
Fentin hydroxide is chemically stable under standard ambient conditions (room temperature).

Possibility of hazardous reactions:
No data available

Conditions to avoid:
no information available

Incompatible materials:
Strong oxidizing agents

First Aid Measures of Fentin hydroxide:

General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.

If inhaled:

After inhalation:
Take a fresh air.
Immediately call in physician.

If breathing stops:
Immediately apply artificial respiration, if necessary also oxygen.

In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.

In case of eye contact:

After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.

If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
In exceptional cases only, if medical care is not available within one hour, induce vomiting (only in persons who are wide awake and fully conscious), administer activated charcoal (20 - 40 g in a 10% slurry) and consult a doctor as quickly as possible.

Indication of any immediate medical attention and special treatment needed:
No data available

Firefighting Measures of Fentin hydroxide:

Suitable extinguishing media:
Water Foam Carbon dioxide (CO2) Dry powder

Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.

Special hazards arising from the substance or mixture:
Carbon oxides
Tin/tin oxides
Combustible.

Development of hazardous combustion gases or vapours possible in the event of fire.

Advice for firefighters
Stay in danger area only with self-contained breathing apparatus.
Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Further information
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.

Accidental Release Measures of Fentin hydroxide:

Personal precautions, protective equipment and emergency procedures:

Advice for non-emergency personnel:
Avoid generation and inhalation of dusts in all circumstances.
Avoid substance contact.

Ensure adequate ventilation.
Evacuate the danger area, observe emergency procedures, consult an expert.

Environmental precautions:
Do not let product enter drains.

Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.

Observe possible material restrictions.
Take up carefully.

Dispose of properly.
Clean up affected area.
Avoid generation of dusts.

Exposure Controls/Personal Protection of Fentin hydroxide:

Personal protective equipment:

Eye/face protection:
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Tightly fitting safety goggles.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested:KCL 741 Dermatril® L

Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Material tested: KCL 741 Dermatril® L

Body Protection:
protective clothing

Respiratory protection:
required when dusts are generated.

Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Recommended Filter type: Filter type P3

The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.
These measures have to be properly documented.

Control of environmental exposure
Do not let product enter drains.

Identifiers of Fentin hydroxide:
CAS Number: 76-87-9
ChEBI: CHEBI:30473
ChEMBL: ChEMBL506538
ChemSpider: 21106510
ECHA InfoCard: 100.000.901
EC Number: 200-990-6
Gmelin Reference: 7194
KEGG: C18729
PubChem CID: 9907219
RTECS number: WH8575000
UNII: KKL46V5313
UN number: 2786 2588
CompTox Dashboard (EPA): DTXSID50215768
InChI:
InChI=1S/3C6H5.H2O.Sn/c3*1-2-4-6-5-3-1;;/h3*1-5H;1H2;/q;;;;+1/p-1
Key: BFWMWWXRWVJXSE-UHFFFAOYSA-M
InChI=1/3C6H5.H2O.Sn/c3*1-2-4-6-5-3-1;;/h3*1-5H;1H2;/q;;;;+1/p-1/rC18H16OSn/c19-20(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15,19H
Key: BFWMWWXRWVJXSE-OLMCWIPIAE
SMILES: O[Sn](c1ccccc1)(c2ccccc2)c3ccccc3

CAS: 76-87-9
Molecular Formula: C18H18OSn
Molecular Weight (g/mol): 369.05
MDL Number: MFCD00013928
InChI Key: ZJIGGMIMCKZRRB-UHFFFAOYSA-N
PubChem CID: 6327657
IUPAC Name: triphenyltin;hydrate
SMILES: O.C1=CC=C(C=C1)[SnH](C1=CC=CC=C1)C1=CC=CC=C1

Properties of Fentin hydroxide:
Chemical formula: C18H16OSn
Molar mass: 367.035 g·mol−1

Quality Level: 100
mp: 124-126 °C (lit.)
SMILES string: O[Sn](c1ccccc1)(c2ccccc2)c3ccccc3
InChI: 1S/3C6H5.H2O.Sn/c3*1-2-4-6-5-3-1;;/h3*1-5H;1H2;/q;;;;+1/p-1
InChI key: BFWMWWXRWVJXSE-UHFFFAOYSA-M

Compound Formula: C18H16OSn
Molecular Weight: 376.03
Appearance: Beige solid
Melting Point: 124-126 °C
Boiling Point: N/A
Density: N/A
Solubility in H2O: N/A

Exact Mass: 368.022 g/mol
Monoisotopic Mass: 368.022 g/mol
Molecular Weight: 368.0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 3
Exact Mass: 369.030143
Monoisotopic Mass: 369.030143
Topological Polar Surface Area: 1 Ų
Heavy Atom Count: 20
Complexity: 207
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

Specifications of Fentin hydroxide:
Color: White
Melting Point: 122°C to 124°C
Linear Formula: (C6H5)3SnOH
UN Number: UN3146
Merck Index: 14,9745
Quantity: 25g
Solubility Information: Slightly soluble in alcohol, toluene
Formula Weight: 367.01
Physical Form: Powder
Chemical Name or Material: Fentin hydroxide

Names of Triphenyltin Hydroxide:

Regulatory process names:
Fentin hydroxide
Fentin hydroxide
fentin hydroxide
fentin hydroxide (ISO)
fentin hydroxide (ISO)
triphenyltin hydroxide

Translated names:
fencín-hydroxid (ISO) (sk)
fentiinhüdroksiid (ISO) (et)
fentin hidroksid (ISO) (hr)
fentin hidroksid (ISO) (sl)
fentin hydroxide (ISO) (cs)
fentin hydroxide (ISO)· (el)
fentin idrossido (ISO) (it)
fentin-hidroxid (ISO) (hu)
fentinahydroksidi (ISO) (fi)
fentinhidroksidas (ISO) (lt)
fentinhidroksīds (ISO) (lv)
fentinhydroksid (no)
fentinhydroxid (ISO) (da)
Fentinhydroxid (ISO) (de)
fentinhydroxid [ISO] (sv)
fentinhydroxide (ISO) (nl)
fentyny wodorotlenek (ISO) (pl)
hidroxid de fentin (ISO) (ro)
hidroxid de trifenilstaniu (ro)
hidróxido de fentina (ISO) (es)
hidróxido de fentina (ISO) (pt)
hidróxido de trifenilestanho (pt)
hidróxido de trifenilestaño (es)
hydroxyde de fentine (ISO);hydroxyde de triphénylétain (fr)
hydroxyde de triphénylétain (fr)
idrossido di trifenilstagno (it)
idrossidu tal-fentin (ISO) (mt)
idrossidu tat-trifeniltin (mt)
trifenilalavo hidroksidas (lt)
trifenilalvas hidroksīds (lv)
trifenilkositrov hidroksid (hr)
trifenilkositrov hidroksid (sl)
trifeniltin-hidroxid (hu)
trifenyl(hydroxyl)stannan (cs)
trifenylcín- hydroxid (cs)
trifenylstanium-hydroxid (sk)
trifenyltennhydroxid (sv)
trifenyltinhydroxide (nl)
trifenyltinnhydroksid (no)
trifenyylitinahydroksidi (fi)
trifenüültinahüdroksiid (et)
triphenyltinhydroxid (da)
Triphenylzinnhydroxid (de)
wodorotlenek trifenylocyny (pl)
υδροξείδιο του τριφαινυλοκασσιτέρου (el)
трифенилкалаен хидроксид (bg)
фентин хидроксид (ISO) (bg)

CAS names:
Stannane
hydroxytriphenyl-

Alternate Chemical Names:
BRESTANID
DOWCO 186
DU-TER
DU-TER W-50
DUTER
ENT 28009
ERITHANE
FENOLOVO
FENTIN HYDROXIDE
HAITIN
HYDROXYTRIPHENYLSTANNANE
HYDROXYTRIPHENYLTIN
K 19
NCI-C00260
OMS 1017
SUNITRON H
SUZU H
TENHIDE
TPTH
TPTOH
TRIPHENYL(HYDROXO)STANNANE
TRIPHENYLHYDROXYTIN
TRIPHENYLSTANNANOL
TRIPHENYLSTANNIUM HYDROXIDE
TRIPHENYLSTANNYL HYDROXIDE
TRIPHENYLTIN HYDROXIDE
TRIPHENYLTIN OXIDE
TUBOTIN
VANCIDE KS

Preferred IUPAC name:
Triphenylstannanol

IUPAC names:
fentin hydroxide (ISO); triphenyltin hydroxide
triphenylstannanol
Triphenyltin Hydroxide
triphenyltin(IV) hydroxide
triphenyltin;hydrate
Ferric Ammonium Citrate
SYNONYMS Iron trichloride; Iron(III) chloride; Iron chloride; Ferric chloride; Flores martis; Iron sesquichloride; Chlorure ferrique; Chlorure perrique; Iron trichloride; Perchlorure de fer; Other RN: 12178-83-5, 130622-20-7 CAS NO. 7705-08-0
Ferric Chloride
Synonyms: Ferric chloride test solution(ChP);Ferric Chloride Manufacturer;perchloruredefer(french);TDA REAGENT;TRYPTOPHAN DEAMINASE REAGENT;BOD IRON(III) CHLORIDE SOLUTION D;FERRIC TRICHLORIDE;Ferric trichloride,solution cas : 7705-08-0
Ferric Chloride Sulfate
SynonymsFERIX-3;NA-9121;BETA FLOC;Fe2(SO4)3;liusuantie;FERAQUA(TM);MONSEL SALT;MONSEL'S SALT;irontersulfate;FERRIC SULFATE CAS No.10028-22-5
Ferric Pyrophosphate
Ferric Pyrophosphate; Iron(III) pyrophosphate 10058-44-3
Ferric Sulfate
SYNONYMS Iron trichloride; Iron(III) chloride; Iron chloride; Ferric chloride; CAS NO. 7705-08-0
Ferro glukonat
SYNONYMS D-g luconic acid iron(II) salt;irox(gador);nionate;ray-gluciron;iron digluconate;Ferrous Gluconate NF, Powder;Ferrous Gluconate USP/FCC, Granular;Ferrous Gluconate, Granular CAS NO:299 – 29 - 6
Ferrous Chloride
FERULIC ACID N° CAS : 1135-24-6 Nom INCI : FERULIC ACID Nom chimique : 4-Hydroxy-3-methoxycinnamic acid N° EINECS/ELINCS : 214-490-0 Compatible Bio (Référentiel COSMOS) Ses fonctions (INCI) Antimicrobien : Aide à ralentir la croissance de micro-organismes sur la peau et s'oppose au développement des microbes Antioxydant : Inhibe les réactions favorisées par l'oxygène, évitant ainsi l'oxydation et la rancidité
Ferrous Fumarate
Fumiron; Ircon; Fumar F; Ferrotemp; Fersamal; cas no :141-01-5
FERROUS SULFATE
Ferrous sulfate is an essential body mineral used to treat iron deficiency anemia (a lack of red blood cells caused by having too little iron in the body).
Ferrous sulfate is an iron supplement used to treat or prevent low blood levels of iron (such as those caused by anemia or pregnancy).
The iron supplement ferrous sulfate is an iron salt with the chemical formula FeSO4.

CAS Number: 7720-78-7
EC Number: 231-753-5
Chemical Formula: FeSO4
Molecular Weight: 151.91

Synonyms: ferrous salt, FERROUS SULFATE, Iron(II) sulfate, 7720-78-7, Iron sulfate, Iron(2+) sulfate, Iron sulphate, Ferrous sulfate anhydrous, Iron sulfate (1:1), Iron(2+) sulphate, FeSO4, Iron(II) sulfate (1:1), Iron sulfate (FeSO4), Ferrous sulfate (1:1), Sulfuric acid, iron(2+) salt (1:1), Sulfuric acid, iron(2+) salt, 2IDP3X9OUD, 16547-58-3, iron(2+) sulfate (anhydrous), Iron vitriol; Iron(2+) sulfate, Combiron, Odophos, Kesuka, Sal chalybis, Quickfloc (salt), Slow Fe, Ferrosulfat [German], Ferrosulfat, CCRIS 6796, HSDB 465, SFE 171, EINECS 231-753-5, UNII-2IDP3X9OUD, NSC 57631, NSC 146177, AI3-51903, FERROUS SULPHATE ANHYDROUS, iron(II)sulphate, Fe(II) sulphate, iron(II) sulphate, EINECS 240-616-9, iron(2+);sulfate, Iron (as sulphate), iron (II) sulphate, Ferrous sulfate,dried, errous hydrogen sulfide, Sulfuric acid, iron(2+) salt (1:?), Iron sulphate (feso4), Ferrous sulfate, 98%, ferrous sulfate (anh.), Fe(II)SO4, Ferrous sulfate, anhydrous, Ferrous sulphate (1:1), EC 231-753-5, Ferrous sulphate, anhydrous, ferrous sulfate (anhydrous), iron(2+) sulfate (anh.), FERROUS SULFATE [MI], Iron(II) sulfate (FeSO4), FERROUS SULFATE [ISO], FERROUS SULFATE [HSDB], DTXSID0029688, CHEBI:75832, FERROUS SULFATE [WHO-DD], Ferrous Sulphate Exsiccated (Dried), IRON(II) SULPHATE (1:1), Tox21_202580, FERROUS SULFATE,DRIED [VANDF], DB13257, NCGC00260129-01, CAS-7720-78-7, FT-0626420, Q214863, 8063-79-4

Ferrous sulfate is a type of iron.
You normally get iron from the foods you eat.

In your body, iron becomes a part of your hemoglobin and myoglobin.
Hemoglobin carries oxygen through your blood to tissues and organs.
Myoglobin helps your muscle cells store oxygen.

Ferrous Sulfate is an essential body mineral.
Ferrous sulfate is used to treat iron deficiency anemia (a lack of red blood cells caused by having too little iron in the body).

Iron(II) sulfate (British English: iron(II) sulphate) or ferrous sulfate denotes a range of salts with the formula Fe SO4·xH2O.
These compounds exist most commonly as the heptahydrate (x = 7) but several values for x are known.

The hydrated form is used medically to treat iron deficiency, and also for industrial applications.
Known since ancient times as copperas and as green vitriol (vitriol is an archaic name for sulfate), the blue-green heptahydrate (hydrate with 7 molecules of water) is the most common form of Ferrous sulfate.

All the iron(II) sulfates dissolve in water to give the same aquo complex [Fe(H2O)6]2+, which has octahedral molecular geometry and is paramagnetic.
The name copperas dates from times when the copper(II) sulfate was known as blue copperas, and perhaps in analogy, iron(II) and zinc sulfate were known respectively as green and white copperas.

Ferrous sulfate is on the World Health Organization's List of Essential Medicines.
In 2020, Ferrous sulfate was the 116th most commonly prescribed medication in the United States, with more than 5 million prescriptions.

Iron, or ferrous sulfate is a mineral that your body needs to produce red blood cells.
When the body does not get enough iron, Ferrous sulfate cannot produce enough red blood cells to keep itself healthy.

This is called iron-deficiency anemia.
Lack of iron can cause tiredness, shortness of breath, and decreased physical performance.
Ferrous sulfate also can increase the chance of a liver transplant patient getting infections.

Ferrous sulfate uses include treating or preventing low levels of iron in the blood; Ferrous sulfate treats or prevents iron-deficiency anemia.

Foods rich in iron include lean red meat, beans, nuts, asparagus, oatmeal, and dried peaches.
Vitamin C can increase the absorption of iron, which can be found in citrus fruits and fresh vegetables.
Ferrous sulfate might be prescribed if your child is not able to maintain a healthy level of iron through diet alone after a liver transplant.

Ferrous sulfate appears as a greenish or yellow-brown crystalline solid.
Ferrous sulfate is density 15.0 lb /gal.
Ferrous sulfate is melts at 64 °C and loses the seven waters of hydration at 90 °C.

Ferrous sulfate is immediate steps should be taken to limit Ferrous sulfate spread to the environment.
Ferrous sulfate is used for water or sewage treatment, as a fertilizer ingredient.

Iron deficiency anemia is a large public health concern worldwide, especially in young children, infants, and women of childbearing age.
This type of anemia occurs when iron intake, iron stores, and iron loss do not adequately support the formation of erythrocytes, also known as red blood cells.

Ferrous sulfate is a synthetic agent used in the treatment of iron deficiency.
Ferrous sulfate is the gold standard of oral iron therapy in the UK and many other countries.

Ferrous sulfate is an iron supplement you may use to treat iron-deficiency anemia.
You may need ferrous sulfate if you don’t get enough iron through the foods you eat.

Ferrous sulfate comes in tablet and liquid form.
Side effects may include constipation, stomach cramps and other digestive issues.
Only take an iron supplement as directed.

Ferrous sulfate is a type of iron supplement.
You normally get all the iron you need from the foods you eat.

Your healthcare provider may recommend ferrous sulfate if you don’t get enough iron in your diet.
Iron supplements can be especially beneficial for women or people assigned female at birth.

A sulfate salt of mineral iron formulated for oral administration and used as a dietary supplement, ferrous sulfate is absorbed in the stomach and small intestine and combines with apoferritin to form ferritin, which is stored in the liver, spleen, red bone marrow, and intestinal mucosa.
Important in transport of oxygen by hemoglobin to the tissues, iron is also found in myoglobin, transferrin, and ferritin, and is a component of many enzymes such as catalase, peroxidase, and cytochromes.

The iron supplement ferrous sulfate is an iron salt with the chemical formula FeSO4.
Iron salts are one type of the mineral iron.
People often use them as a supplement to treat iron deficiency.

Ferrous sulfate is also called iron sulfate, green vitriol, and iron vitriol.
This article is an overview of ferrous sulfate, Ferrous sulfate benefits and side effects, and how you can use Ferrous sulfate to treat and prevent iron deficiency.

Ferrous sulfate is just one of many forms of the metal element iron.

In Ferrous sulfate natural state, the solid mineral resembles small crystals.
The crystals are typically a shade of yellow, brown, or bluish-green — hence why ferrous sulfate is sometimes called green vitriol.

Supplement makers use multiple types of iron in dietary supplements.
Aside from ferrous sulfate, the most common are ferrous gluconate, ferric citrate, and ferric sulfate.

Most types of iron in supplements are in one of two forms — ferric or ferrous.
This depends on the chemical state of the iron atoms.

The body absorbs ferrous forms of iron better than ferric forms.
Thus, healthcare providers often consider ferrous forms, including ferrous sulfate, to be the best choice for iron supplements.

Ferrous Sulfate is a mineral salt of iron, a dietary mineral essential for the production of red blood cells.
Iron is a mineral in our blood cells responsible for transporting and storing needed oxygen.

Ferrous sulfate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 000 to < 10 000 000 tonnes per annum.
Ferrous sulfate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Ferrous Sulfate is available in over-the-counter vitamin supplements both individually and in combination with other nutrients.
Ferrous Sulfate is also sometimes used in prescription Ferrous Sulfate supplements that treat iron-deficient anemia (low numbers of red blood cells caused by low iron).

Ferrous sulfate is an iron salt popularly known as green vitriol.
Imferon and iron dextran are injectable iron.

Ferrous fumarate, ferrous gluconate, and ferrous sulfate are generic names for oral iron.
Ferrous sulfate is by far the best and cheapest for iron supplement.

Ferrous sulfate is formed when iron filings are mixed into a solution of copper sulfate, iron pushes the copper since Ferrous sulfate is more reactive and takes Ferrous sulfate place resulting in the formation of iron sulfate.

Uses of Ferrous sulfate:
Ferrous sulfate is used as iron supplements are indicated in patients with diseases caused by iron deficiency.
Ferrous sulfate is used in the treatment of iron deficiency anaemia, prophylaxis for iron deficiency in pregnancy.

Ferrous sulfate is used in precaution if sedation or general anaesthesia is required; risk of the hypotensive episode.
Ferrous sulfate can also be used with chlorine.
This treatment is normally known as chlorinated copperas treatment.

Ferrous sulfate is used as a mordant in textile dyeing.
Ferrous sulfate is used to make iron compounds and in engraving, lithography, water treatment, aluminum etching, and qualitative analysis (brown ring test for nitrates).

Ferrous sulfate is also used in iron electroplating baths, fertilizers and pesticides, food and feed supplements, radiation dosimeters, wood preservative, inks, leather dyes, polymerization catalysts, and pharmaceuticals (iron deficiency anemia).
Ferrous sulfate is used as iron oxide pigment, catalyst (especially for synthetic ammonia), and food supplement.

Ferrous sulfate is an iron supplement used to treat or prevent low blood levels of iron (such as those caused by anemia or pregnancy).
Iron is an important mineral that the body needs to produce red blood cells and keep you in good health.

Industrially, ferrous sulfate is mainly used as a precursor to other iron compounds.
Ferrous sulfate is a reducing agent, and as such is useful for the reduction of chromate in cement to less toxic Cr(III) compounds.

Historically ferrous sulfate was used in the textile industry for centuries as a dye fixative.
Ferrous sulfate is used historically to blacken leather and as a constituent of iron gall ink.
The preparation of sulfuric acid ('oil of vitriol') by the distillation of green vitriol (iron(II) sulfate) has been known for at least 700 years.

Medical use:
Follow all directions on Ferrous sulfate package, or take as directed by your doctor.
Do not take more than the recommended dosage.
If you have any questions, ask your doctor or pharmacist.

Iron is best absorbed on an empty stomach (usually if taken 1 hour before or 2 hours after meals).
If stomach upset occurs, you may take this medication with food.

See the instructions below for the liquid drops for infants/children.
Avoid taking antacids, dairy products, tea, or coffee within 2 hours before or after this medication because they will decrease Ferrous sulfate effectiveness.

Take tablets or capsules with a full glass of water (8 ounces or 240 milliliters) unless otherwise directed by your doctor.
Do not lie down for at least 10 minutes after taking your tablet or capsule dose.

Swallow extended-release capsules whole.
Do not crush or chew extended-release capsules or tablets.

Doing so can release all of the drug at once, increasing the risk of side effects.
Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so.
Swallow the whole or split tablet without crushing or chewing.

If you are taking chewable tablets, chew the medication thoroughly, then swallow.
If you are taking a liquid suspension form of this medication, shake the bottle well before each dose.

If you are taking the liquid form for adults, carefully measure the dose using a special measuring device/spoon.
Do not use a household spoon because you may not get the correct dose.
Mix the dose in a glass of water or juice, and drink the mixture through a straw to prevent staining the teeth.

If you are giving the liquid drops to an infant or child, use the dropper provided to carefully measure the dose.
The dose may be placed directly into the mouth (towards the back of the tongue) or Ferrous sulfate may be mixed in formula (not milk), fruit juice, cereal, or other food as directed to increase your child's acceptance.

Ferrous sulfate is best to give this medication right after a meal.
Follow the directions on Ferrous sulfate package for the brand that you use.

Take this medication regularly in order to get the most benefit from Ferrous sulfate.
To help you remember, take Ferrous sulfate at the same time(s) each day.

Before taking this medicine:

Ask a doctor or pharmacist if ferrous sulfate is safe to use if you have ever had:
Iron overload syndrome,
A red blood cell disorder such as thalassemia,
A condition for which you receive regular blood transfusions.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.
Do not give ferrous sulfate to a child without medical advice.

Plant growth:
Ferrous sulfate is sold as ferrous sulfate, a soil amendment for lowering the pH of a high alkaline soil so that plants can access the soil's nutrients.

In horticulture Ferrous sulfate is used for treating iron chlorosis.
Although not as rapid-acting as ferric EDTA, Ferrous sulfate effects are longer-lasting.

Ferrous sulfate can be mixed with compost and dug into the soil to create a store which can last for years.
Ferrous sulfate can be used as a lawn conditioner.
Ferrous sulfate can also be used to eliminate silvery thread moss in golf course putting greens.

Pigment and craft:
Ferrous sulfate can be used to stain concrete and some limestones and sandstones a yellowish rust color.
Woodworkers use ferrous sulfate solutions to color maple wood a silvery hue.
Green vitriol is also a useful reagent in the identification of mushrooms.

Historical uses:
Ferrous sulfate was used in the manufacture of inks, most notably iron gall ink, which was used from the middle ages until the end of the 18th century.
Chemical tests made on the Lachish letters (c. 588–586 BCE) showed the possible presence of iron.

Ferrous sulfate is thought that oak galls and copperas may have been used in making the ink on those letters.
Ferrous sulfate also finds use in wool dyeing as a mordant.
Harewood, a material used in marquetry and parquetry since the 17th century, is also made using ferrous sulfate.

Two different methods for the direct application of indigo dye were developed in England in the 18th century and remained in use well into the 19th century.
One of these, known as china blue, involved Ferrous sulfate.

After printing an insoluble form of indigo onto the fabric, the indigo was reduced to leuco-indigo in a sequence of baths of ferrous sulfate (with reoxidation to indigo in air between immersions).
The china blue process could make sharp designs, but Ferrous sulfate could not produce the dark hues of other methods.

In the second half of the 1850s ferrous sulfate was used as a photographic developer for collodion process images.

Used to treat iron deficiency anemia:
Anemia is a condition that occurs when your blood has low amounts of red blood cells or hemoglobin.
Because iron is a critical part of the red blood cells responsible for transporting oxygen throughout the body, having iron deficiency is one of the most common causes of anemia.

Iron deficiency anemia (IDA) is a severe form of iron deficiency that has significant effects on the human body and may cause some of the more serious symptoms associated with iron deficiency.
One of the most common and effective treatments for IDA is taking an oral iron supplement, such as ferrous sulfate.

Might improve surgical outcomes:
Multiple research studies have cited having iron deficiency as a risk factor for increased rates of complications and mortality following surgery.
One study looked at the outcomes for 730 people who underwent heart surgery, including those with ferritin levels below 100 mcg per liter — a sign of iron deficiency.

The iron deficient participants were more likely to experience serious adverse events during surgery, including death.
They also required a longer stay in the hospital, on average, after surgery.

Iron deficiency appears to have similar effects in other types of surgery.
One study analyzed more than 227,000 surgical procedures and determined that even mild IDA prior to surgery increased the risk of health complications and mortality following the procedure.

Because ferrous sulfate supplements can treat and prevent iron deficiency, taking them prior to having surgery could improve the outcome and reduce the risk of complications.
However, Ferrous sulfate may take time to increase iron levels via supplementation.

Though oral iron supplements like ferrous sulfate are an effective way to increase iron stores in the body, a person may need to take supplements every day for 2–5 months to bring their iron stores up to normal levels.
Thus, people with iron deficiency who do not have multiple months to try and increase iron stores prior to surgery may not benefit from ferrous sulfate supplements and require another type of iron therapy instead.

Furthermore, research studies on iron therapy for people who have anemia before surgery are limited in size and scope.
Scientists still need to conduct more high quality studies to investigate the best ways for people to increase their iron levels before surgery.

Biocidal Uses:
Ferrous sulfate is approved in the EEA and/or Switzerland for use in biocidal products more favourable for the environment, human or animal health.

Consumer Uses:
Ferrous sulfate is used in the following products: fertilisers, fillers, putties, plasters, modelling clay, plant protection products, adhesives and sealants and metal surface treatment products.
Other release to the environment of Ferrous sulfate is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

Widespread uses by professional workers:
Ferrous sulfate is used in the following products: fertilisers, pH regulators and water treatment products, laboratory chemicals, water treatment chemicals, metal surface treatment products, plant protection products and fillers, putties, plasters, modelling clay.
Ferrous sulfate has an industrial use resulting in manufacture of another substance (use of intermediates).

Ferrous sulfate is used in the following areas: agriculture, forestry and fishing, building & construction work, scientific research and development and formulation of mixtures and/or re-packaging.
Ferrous sulfate is used for the manufacture of: mineral products (e.g. plasters, cement).
Other release to the environment of Ferrous sulfate is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

Uses at industrial sites:
Ferrous sulfate is used in the following products: pH regulators and water treatment products, water treatment chemicals, laboratory chemicals, fillers, putties, plasters, modelling clay, fertilisers and metal surface treatment products.
Ferrous sulfate has an industrial use resulting in manufacture of another substance (use of intermediates).

Ferrous sulfate is used in the following areas: formulation of mixtures and/or re-packaging, building & construction work and scientific research and development.
Ferrous sulfate is used for the manufacture of: chemicals, metals, fabricated metal products, electrical, electronic and optical equipment and mineral products (e.g. plasters, cement).
Release to the environment of Ferrous sulfate can occur from industrial use: in the production of articles, in processing aids at industrial sites, as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates) and formulation of mixtures.

Industrial Processes with risk of exposure:
Electroplating
Painting (Pigments, Binders, and Biocides)
Applying Wood Preservatives
Sewer and Wastewater Treatment
Textiles (Printing, Dyeing, or Finishing)
Farming (Feed Additives)

Activities with risk of exposure:
Textile arts
Lithography printing

Benefits of Ferrous sulfate:
The primary benefit of taking ferrous sulfate supplements is to maintain normal iron levels in the body.
Doing so may prevent you from experiencing iron deficiency, as well as the range of mild to severe side effects that often accompany Ferrous sulfate.

Here’s a closer look at the benefits of taking ferrous sulfate supplements.

Helps maintain normal blood iron levels:
Iron is one of the most common elements on earth, and Ferrous sulfate’s an essential mineral.
That means people need to consume Ferrous sulfate in their diet for optimal health.

The body primarily uses iron as part of the red blood cell proteins myoglobin and hemoglobin, which are essential for transporting and storing oxygen.
Iron also plays an important role in the formation of hormones, the health and development of the nervous system, and basic cell functioning

Although many people consume iron as a dietary supplement, you can also find Ferrous sulfate naturally in many foods, including beans, spinach, potatoes, tomatoes, and particularly meat and seafood, including oysters, sardines, poultry, and beef.
Some foods, such as fortified breakfast cereals, are not naturally high in iron, but manufacturers add iron to make them a good source of this mineral.

Many of the highest sources of iron are animal products.
Therefore, vegans, vegetarians, and people who do not consume many iron-rich foods as a part of their normal diet may benefit from taking ferrous sulfate iron supplements to help maintain their iron stores.

May prevent symptoms of iron deficiency:
Taking ferrous sulfate supplements is a simple way to treat, prevent, or reverse low blood iron levels.

Preventing iron deficiency not only ensures that your body has enough of the essential nutrient to continue functioning properly but also can help you avoid many of the unpleasant side effects of low iron levels.

Some of the most notable side effects of low iron levels include:
Fatigue
Headaches
Feeling weak
Low energy levels
Difficulty concentrating
Difficulty thinking clearly
Hair loss
Brittle nails
Upset stomach
Poor immunity
Heart palpitations
Restless leg syndrome
Shortness of breath
The inability to regulate body temperature
Pica, an urge to eat nonfood items, such as paint or soap

This is a general overview — not a comprehensive list — of all the symptoms of low iron levels.
Symptoms may worsen as an iron deficiency progresses from mild to severe.

Chemical Properties of Ferrous sulfate:
Ferrous sulfate reacts with aluminium under displacement reaction forming aluminium sulfate and metallic iron.

The chemical reaction is given below.
2Al + 3FeSO4 → Al2(SO4)3 + 3Fe

Ferrous sulfate reacts with potassium permanganate in the presence of sulphuric acid forms ferric sulfate, manganese sulfate, potassium sulfate, and water.
10FeSO4 + 2KMnO4 + 8H2SO4 → 5Fe2(SO4)3 + 2MnSO4 + 8H2O + K2SO4

Hydrates of Ferrous sulfate:
Ferrous sulfate can be found in various states of hydration, and several of these forms exist in nature or were created synthetically.

FeSO4·H2O (mineral: szomolnokite, relatively rare, monoclinic)
FeSO4·H2O (synthetic compound stable at pressures exceeding 6.2 GPa, triclinic)

FeSO4·4H2O (mineral: rozenite, white, relatively common, may be dehydration product of melanterite, monoclinic)
FeSO4·5H2O (mineral: siderotil, relatively rare, triclinic)

FeSO4·6H2O (mineral: ferrohexahydrite, very rare, monoclinic)
FeSO4·7H2O (mineral: melanterite, blue-green, relatively common, monoclinic)

The tetrahydrate is stabilized when the temperature of aqueous solutions reaches 56.6 °C (133.9 °F). At 64.8 °C (148.6 °F) these solutions form both the tetrahydrate and monohydrate.

Mineral forms are found in oxidation zones of iron-bearing ore beds, e.g. pyrite, marcasite, chalcopyrite, etc.
They are also found in related environments, like coal fire sites.

Many rapidly dehydrate and sometimes oxidize.
Numerous other, more complex (either basic, hydrated, and/or containing additional cations) Fe(II)-bearing sulfates exist in such environments, with copiapite being a common example.

Production and Reactions of Ferrous sulfate:
In the finishing of steel prior to plating or coating, the steel sheet or rod is passed through pickling baths of sulfuric acid.

This treatment produces large quantities of Ferrous sulfate as a by-product.
Fe + H2SO4 → FeSO4 + H2

Another source of large amounts results from the production of titanium dioxide from ilmenite via the sulfate process.

Ferrous sulfate is also prepared commercially by oxidation of pyrite:
2 FeS2 + 7 O2 + 2 H2O → 2 FeSO4 + 2 H2SO4

Ferrous sulfate can be produced by displacement of metals less reactive than Iron from solutions of their sulfate:
CuSO4 + Fe → FeSO4 + Cu

Reactions:
Upon dissolving in water, ferrous sulfates form the metal aquo complex [Fe(H2O)6]2+, which is an almost colorless, paramagnetic ion.

On heating, Ferrous sulfate first loses Ferrous sulfate water of crystallization and the original green crystals are converted into a white anhydrous solid.
When further heated, the anhydrous material decomposes into sulfur dioxide and sulfur trioxide, leaving a reddish-brown iron(III) oxide.
Thermolysis of Ferrous sulfate begins at about 680 °C (1,256 °F).

2FeSO4→ΔFe2O3+SO2+SO3

Like other iron(II) salts, Ferrous sulfate is a reducing agent.

For example, Ferrous sulfate reduces nitric acid to nitrogen monoxide and chlorine to chloride:
6 FeSO4 + 3 H2SO4 + 2 HNO3 → 3 Fe2(SO4)3 + 4 H2O + 2 NO
6 FeSO4 + 3 Cl2 → 2 Fe2(SO4)3 + 2 FeCl3

Ferrous sulfate mild reducing power is of value in organic synthesis.
Ferrous sulfate is used as the iron catalyst component of Fenton's reagent.

Ferrous sulfate can be detected by the cerimetric method, which is the official method of the Indian Pharmacopoeia.
This method includes the use of ferroin solution showing a red to light green colour change during titration.

Pharmacology and Biochemistry of Ferrous sulfate:

Pharmacodynamics:
Ferrous sulfate replenishes iron, an essential component in hemoglobin, myoglobin, and various enzymes.
Ferrous sulfate replaces the iron that is usually found in hemoglobin and myoglobin.
Iron participates in oxygen transport and storage, electron transport and energy metabolism, antioxidant and beneficial pro-oxidant functions, oxygen sensing, tissue proliferation and growth, as well as DNA replication and repair.

Action Mechanism of Ferrous sulfate:
Iron is required to maintain optimal health, particularly for helping to form red blood cells (RBC) that carry oxygen around the body.
A deficiency in iron indicates that the body cannot produce enough normal red blood cells.

Iron deficiency anemia occurs when body stores of iron decrease to very low levels, and the stored iron is insufficient to support normal red blood cell (RBC) production.
Insufficient dietary iron, impaired iron absorption, bleeding, pregnancy, or loss of iron through the urine can lead to iron deficiency.
Symptoms of iron deficiency anemia include fatigue, breathlessness, palpitations, dizziness, and headache.

Taking iron in supplement form, such as ferrous sulfate, allows for more rapid increases in iron levels when dietary supply and stores are not sufficient.
Iron is transported by the divalent metal transporter 1 (DMT1) across the endolysosomal membrane to enter the macrophage.

Ferrous sulfate can then can be incorporated into ferritin and be stored in the macrophage or carried of the macrophage by ferroportin.
This exported iron is oxidized by the enzyme to ceruloplasmin to Fe3+, followed by sequestration by transferrin for transport in the serum to various sites, including the bone marrow for hemoglobin synthesis or into the liver.
Iron combines with porphyrin and globin chains to form hemoglobin, which is critical for oxygen delivery from the lungs to other tissues.

Absorption of Ferrous sulfate:
Approximately 5 – 10% of dietary iron is absorbed, and this absorption rate increases to up to 30% in iron deficiency states.
Oral iron supplements are absorbed up to 60% via active and passive transport processes.

Gastrointestinal absorption of iron occurs via strict regulation by the enterocyte and duodenal cytochrome and ferric reductase enzymes.
The hormone hepcidin heavily regulates iron absorption and distribution throughout the body.

The median time to maximum serum concentration (Tmax) is generally 4 hours after administration.
Between 2-8 hours post administration, average serum iron concentrations fluctuate by 20%, according to one study.

Bioavailability of iron depends on whether Ferrous sulfate is administered in a film coated tablet or enteric coated tablet.
One pharmacokinetic study in healthy volunteers revealed a 30% bioavailability for enteric coated tablets.

The AUC of enteric coated tablets varied between a lower limit of -46.93 to 5.25 µmolxh/l.
Cmax is higher for film coated tablets, ranging from 3.4 to 22.1 µmol/h/l.

Ferrous sulfate is advisable to take ferrous sulfate with ascorbic acid, as this practice may increase absorption.
Avoid antacids, tea, coffee,tea, dairy products, eggs, and whole-grain bread for at least an hour after taking ferrous sulfate.
Calcium can decrease iron absorption by 33% if taken concomitantly.

First Aid Measures of Ferrous sulfate:

INGESTION:
Give milk immediately and then induce vomiting by stroking the pharynx with a blunt object such as a spoon handle.
Gastric lavage with 1 pint of 5% aqueous solution of mono- or disodium phosphate if promptly available; otherwise use water.
Get medical attention.

Fire Fighting of Ferrous sulfate:

If material involved in fire:
Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.)

Accidental Release Measures of Ferrous sulfate:

Environmental considerations:

Water spill:
Adjust pH to neutral (pH= 7).
Allow to aerate.

Neutralize with agricultural lime (CaO), crushed limestone (CaCO3), or sodium bicarbonate (NaHCO3).
Adjust pH to neutral (pH= 7).
Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.

Environmental considerations:

Land spill:
Dig a pit, pond, lagoon, holding rea to contain liquid or solid material.
If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner.
Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water.

Disposal Methods of Ferrous sulfate:
The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination.
Recycle any unused portion of the material for Ferrous sulfate approved use or return Ferrous sulfate to the manufacturer or supplier.

Ultimate disposal of the chemical must consider:
The material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

Precipitation and landfill:
Treat water or scrap material with soda ash or dilute sodium hydroxide to precipitate iron.
Separate the precipitate and dispose of in an approved landfill.

Identifiers of Ferrous sulfate:
CAS Number:
Anhydrous: 7720-78-7
Monohydrate: 17375-41-6
Dihydrate: 10028-21-4
Heptahydrate: 7782-63-0

ChEBI:
Anhydrous: CHEBI:75832
ChEMBL:
Anhydrous: ChEMBL1200830

ChemSpider:
Anhydrous: 22804
Monohydrate: 56459
Heptahydrate: 22804

ECHA InfoCard: 100.028.867
EC Number:
Anhydrous: 231-753-5

PubChem CID:
Anhydrous: 24393
Monohydrate: 62712
Heptahydrate: 62662

RTECS number Anhydrous:
NO8500000 (anhydrous)
NO8510000 (heptahydrate)

UNII:
Anhydrous: 2IDP3X9OUD
Monohydrate: RIB00980VW
Dihydrate: G0Z5449449
Heptahydrate: 39R4TAN1VT

UN number: 3077
CompTox Dashboard (EPA) anhydrous: DTXSID0029688
InChI: InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2
Key: BAUYGSIQEAFULO-UHFFFAOYSA-L

Anhydrous: InChI=1/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2
Key: BAUYGSIQEAFULO-NUQVWONBAS
SMILES anhydrous: [O-]S(=O)(=O)[O-].[Fe+2]

EC / List no.: 231-753-5
CAS no.: 7720-78-7

Synonyms: Iron(II) sulfate heptahydrate, Ferrous sulfate heptahydrate
Linear Formula: FeSO4 · 7H2O
CAS Number: 7782-63-0
Molecular Weight: 278.01

Properties of Ferrous sulfate:
Chemical formula: FeSO4

Molar mass:
151.91 g/mol (anhydrous)
169.93 g/mol (monohydrate)
241.99 g/mol (pentahydrate)
260.00 g/mol (hexahydrate)
278.02 g/mol (heptahydrate)

Appearance: White crystals (anhydrous)
White-yellow crystals (monohydrate)
Blue-green crystals (heptahydrate)

Odor: Odorless

Density:
3.65 g/cm3 (anhydrous)
3 g/cm3 (monohydrate)
2.15 g/cm3 (pentahydrate)
1.934 g/cm3 (hexahydrate)
1.895 g/cm3 (heptahydrate)

Melting point:
680 °C (1,256 °F; 953 K) (anhydrous) decomposes
300 °C (572 °F; 573 K) (monohydrate) decomposes
60–64 °C (140–147 °F; 333–337 K) (heptahydrate) decomposes

Solubility in water: Monohydrate:
44.69 g/100 mL (77 °C)
35.97 g/100 mL (90.1 °C)

Heptahydrate:
15.65 g/100 mL (0 °C)
19.986 g/100 mL (10 °C)
29.51 g/100 mL (25 °C)
39.89 g/100 mL (40.1 °C)
51.35 g/100 mL (54 °C)

Solubility: Negligible in alcohol
Solubility in ethylene glycol: 6.38 g/100 g (20 °C)
Vapor pressure: 1.95 kPa (heptahydrate)

Magnetic susceptibility (χ):
1.24×10−2 cm3/mol (anhydrous)
1.05×10−2 cm3/mol (monohydrate)
1.12×10−2 cm3/mol (heptahydrate)
+10200×10−6 cm3/mol

Refractive index (nD):
1.591 (monohydrate)
1.526–1.528 (21 °C, tetrahydrate)
1.513–1.515 (pentahydrate)
1.468 (hexahydrate)
1.471 (heptahydrate)

Molecular Weight: 151.91
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0
Exact Mass: 151.886665
Monoisotopic Mass: 151.886665
Topological Polar Surface Area: 88.6 Ų
Heavy Atom Count: 6
Complexity: 62.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

Structure of Ferrous sulfate:
Crystal structure:
Orthorhombic, oP24 (anhydrous)
Monoclinic, mS36 (monohydrate)
Monoclinic, mP72 (tetrahydrate)
Triclinic, aP42 (pentahydrate)
Monoclinic, mS192 (hexahydrate)
Monoclinic, mP108 (heptahydrate)

Space group:
Pnma, No. 62 (anhydrous)
C2/c, No. 15 (monohydrate, hexahydrate)
P21/n, No. 14 (tetrahydrate)
P1, No. 2 (pentahydrate)
P21/c, No. 14 (heptahydrate)

Point group:
2/m 2/m 2/m (anhydrous)
2/m (monohydrate, tetrahydrate, hexahydrate, heptahydrate)
1 (pentahydrate)

Lattice constant:
a = 8.704(2) Å, b = 6.801(3) Å, c = 4.786(8) Å (293 K, anhydrous)
α = 90°, β = 90°, γ = 90°

Coordination geometry: Octahedral (Fe2+)

Thermochemistry of Ferrous sulfate:
Heat capacity (C): 100.6 J/mol·K (anhydrous) 394.5 J/mol·K (heptahydrate)
Std molarbentropy (S⦵298): 107.5 J/mol·K (anhydrous) 409.1 J/mol·K (heptahydrate)
Std enthalpy of formation (ΔfH⦵298): −928.4 kJ/mol (anhydrous) −3016 kJ/mol (heptahydrate)
Gibbs free energy (ΔfG⦵): −820.8 kJ/mol (anhydrous) −2512 kJ/mol (heptahydrate)

Related compounds of Ferrous sulfate:
Iron(III) sulfate

Other cations:
Cobalt(II) sulfate
Copper(II) sulfate
Manganese(II) sulfate
Nickel(II) sulfate

Names of Ferrous sulfate:

Regulatory process names:
ferrous sulfate heptahydrate
Ferrous sulphate
iron (II) sulfate
iron (II) sulfate (1:1) heptahydrate
Iron (II) sulphate
Iron sulfate
Iron sulphate
Iron sulphate
iron sulphate
Iron(II)sulfate anhydrous
Sulfuric acid, iron(2+) salt (1:1)
sulfuric acid, iron(II) salt (1:1), heptahydrate

Translated names:
acid sulfuric, sare de fier(II) (1:1), heptahidrat (ro)
acide sulfurique, sel de fer (II) (1:1), heptahydrate (fr)
Dzelzs sulfāts (lv)
dzelzs(II) sulfāta (1:1) heptahidrāts (lv)
dzelzs(II) sulfāta heptahidrāts (lv)
dzelzs(II) sulfāts (lv)
Eisen(II)-sulfat (de)
Eisen(II)sulfat(1:1)heptahydrat (de)
Eisensulfat (de)
Eisensulfatheptahydrat (de)
fero sulfat heptahidrat (hr)
ferrosulfaat heptahydraat (nl)
ferrosulfaattiheptahydraatti (fi)
ferrosulfat heptahydrat (da)
ferrosulfatheptahydrat (no)
ferrous sulfate heptahydrate (mt)
geležies (II) sulfatas (lt)
geležies (II) sulfatas (1:1) heptahidratas (lt)
Geležies sulfatas (lt)
geležies sulfatas, heptahidratas (lt)
heptahydrát síranu železnatého (sk)
ijzer(II)sulfaat (nl)
ijzer(II)sulfaat (1:1) heptahydraat (nl)
IJzersulfaat (nl)
iron (II) sulfate (1:1) heptahydrate (mt)
Iron sulphate (no)
jern(II)sulfat (da)
jern(II)sulfat (no)
jern(II)sulfat (1:1) heptahydrat (da)
jern(II)sulfat (1:1) heptahydrat (no)
Jernsulfat (da)
järn(II)sulfat (sv)
järn(II)sulfat, heptahydrat (sv)
Järnsulfat (sv)
järnsulfatheptahydrat (sv)
kwas siarkowy(VI), sól żelaza(II) (1:1), heptahydrat (pl)
kyselina sírová, železnatá soľ, heptahydrát (sk)
kénsav, vas(II)-só, (1:1) heptahidrát (hu)
raud(II)sulfaat (et)
raud(II)sulfaat (1:1), heptahüdraat (et)
raud(II)sulfaatheptahüdraat (et)
Raudsulfaat (et)
Rauta(II)sulfaatti (fi)
Rauta(II)sulfaattiheptahydraatti (fi)
Rautasulfaatti (fi)
Biocidal active substances
sal de ferro (II) (1:1) de ácido sulfúrico, hepta-hidratado (pt)
sale di ferro (II) di acido solforico, eptaidrato (it)
Schwefelsäure, Eisen(II)salz (1:1), Heptahydrat (de)
Siarczan żelaza (pl)
siarczan żelaza (II) (pl)
siarczan żelazawy heptahydrat (pl)
sieros rūgštis, geležies(II) druska (1:1), heptahidratas (lt)
Solfato di ferro (it)
solfato di ferro (II) (it)
solfato di ferro (II) eptaidrato (it)
solfato ferroso eptaidrato (it)
Sulfat de fier (ro)
sulfat de fier (II) (1:1) heptahidrat (ro)
sulfat de fier(II) (ro)
sulfat feros heptahidrat (ro)
Sulfat tal-ħadid (mt)
sulfat tal-ħadid (II) (mt)
Sulfate de fer (fr)
sulfate de fer (II) (fr)
sulfate de fer (II), heptahydrate (1:1) acide sulfurique, sel de fer(II) (1:1), heptahydratesulfate ferreux, heptahydrate (fr)
sulfate ferreux , heptahydrate (fr)
Sulfato de ferro (pt)
sulfato de ferro (II) (pt)
sulfato de ferro (II) (1:1) heptahidratado (pt)
Sulfato de hierro (es)
sulfato de hierro (II) (es)
sulfato de hierro (II), heptahidrato (es)
sulfato ferroso hepta-hidratado (pt)
sulfato ferroso, heptahidrato (es)
sulfuric acid, iron(II) salt (1:1), heptahydrate (mt)
sumporna kiselina, željezova(II) sol (1:1), heptahidrat (hr)
svavelsyra, järn(II)salt (1:1), heptahydrat (sv)
svovelsyre, jern(II)salt (1:1), heptahydrat (no)
svovlsyre, jern(II)-salt (1:1), heptahydrat (da)
Síran železnatý (cs)
síran železnatý (cs)
Síran železnatý (sk)
síran železnatý (sk)
síran železnatý (1:1) heptahydrát (cs)
síran železnatý heptahydrát (cs)
sērskābes dzelzs(II) sāls (1:1), heptahidrāts (lv)
vas(II)-szulfát (hu)
vas(II)-szulfát (1:1) heptahidrát (hu)
vas(II)-szulfát, heptahidrát (hu)
Vas-szulfát (hu)
väävelhappe raud(II)sool (1:1), heptahüdraat (et)
zwavelzuur, ijzer(II)zout, (1:1) heptahydraat (nl)
ácido sulfúrico, sal de hierro (II), heptahidrato (es)
železnatá sůl kyseliny sírové (1:1), heptahydrát (cs)
železov (II) sulfat (sl)
železov (II) sulfat (1:1) heptahidrat, (sl)
Železov sulfat (sl)
železov sulfat heptahidrat (sl)
železova(II) sol (1:1) žveplove kisline, heptahidrat (sl)
Željezov sulfat (hr)
željezov(II) sulfat (hr)
željezov(II) sulfat (1:1) heptahidrat (hr)
άλας θειικού οξέος με σίδηρο(ΙΙ) (1:1), επταένυδρο (el)
Θειικός σίδηρος (el)
θειικός σίδηρος (ΙΙ) (el)
θειικός σίδηρος(ΙΙ) (1:1), επταένυδρος (el)
θειικός υποσίδηρος, επταένυδρος (el)
железен (II) сулфат (bg)
железен (II) сулфат (1:1) хептахидрат (bg)
Железен сулфат (bg)
C&L Inventory
C&L Inventory
Sulfuric acid, iron(2+) salt (1:1)

IUPAC names:
Eisen(II)sulfat heptahydrat
Ferrosulfate, Copperas
Ferrous sulfate
Ferrous sulfate
Ferrous sulfate (1:1)
Ferrous sulfate heptahydrate
ferrous sulfate heptahydrate
Ferrous sulfate heptahydrate
ferrous sulphate
Ferrous Sulphate
Ferrous sulphate
Ferrous Sulphate Monohydrate
ferrous sulphate, ferrous sulfate, iron sulfate, ferric sulfate, iron(II)sulfate
GFU Iron(II)sulphate
iron (2+) sulfate
iron (2+) sulfate heptahydrate
iron (2+) sulphate
Iron (II) sulfate
iron (II) sulfate
iron (II) sulfate (1:1) heptahydrate
IRON (II) SULFATE HEPTAHYDRATE
iron (II) sulfate heptahydrate
Iron (II) sulfate heptahydrate
iron (II) sulphate
iron (II) sulphate monohydrate
Iron (II)sulfato hydrate
iron sulfate
Iron sulfate
iron sulfate heptahydrate
Iron Sulphate
Iron sulphate
iron sulphate
Iron Sulphate
Iron sulphate
iron sulphate
iron sulphate (technical grade)
iron sulphate heptahydrate
iron sulphate hydrates SBE (by-product of the steel industry where the pickling process are used to clean the metal surface placed on the market)
Iron sulphate, Ferrous sulfate
Iron(+2) cation sulfate
iron(2+) sulfate
iron(2+) sulfate
Iron(2+) sulfate heptahydrate
iron(2+) sulfate heptahydrate
iron(2+) sulfate monohydrate
iron(2+);sulfate;heptahydrate
Iron(II) sulfate
Iron(II) sulfate
Iron(II) sulfate heptahydrate
iron(II) sulfate heptahydrate
Iron(II) sulfate or Iron(2+) sulfate
iron(II) sulphate
iron(II)sulfate
iron(II)sulfate heptahydrate
Iron(III) sulfate
iron; sulfuric acid
iron;sulfuric acid
siarczan żalazawy
solfato di ferro (II) eptaidrato
Sulfuric acid, iron(2+) salt (1:1)
sulfuric acid, iron(II) salt (1:1), heptahydrate
Síran železnatý bezvodý, mono(hepta)hydrátIron Sulphate unhydrous, monohydrous, heptahydrous
Vas(II)-szulfát-heptahidrát
Zelená skalice

Trade names:
[CZ] Skalice zelená
[EN] Green Vitriol
Caparrosa
Coagulant
Combiron
Copperas
Dechromator
Duretter
Duroferon
Eisensulfat Feinkristallin Heptahydrat FeSO4.7 H2O
Eisensulfat Feinkristallin Heptahydrat FeSO4.7 H2O, rieselfähig
Exsiccated ferrous sulfate
Exsiccated ferrous sulphate
Feofol Spansule
Feosol
Feospan
Fer-In-Sol
Fero-Folic 500
Ferralyn
Ferro-Gradumet
Ferro-Theron
FERROGRANUL 20
FERROGRANUL 30
Ferromyn
FERROPOWDER 30
FERROSALT 18
Ferrosand
Ferrosulfaatti, Kemwater COP
Ferrosulfate
Ferrous sulfate
Ferrous sulfate (1:1)
Ferrous sulfate dried
Ferrous sulfate heptahydrate
Ferrous Sulphate
Ferrous sulphate
Ferrous sulphate heptahydrate
ferrous sulphate heptahydrate
Ferrous sulphate microcrystalline Heptahydrate FeSO4.7H2O
Ferrous sulphate microcrystalline Heptahydrate FeSO4.7H2O, freeflowing
Ferrous Sulphate Monohydrate
Ferrous sulphate monohydrate
ferrous sulphate monohydrate
Fersolate
FESPOL 20
FESPOL 28
Green Salts
Green vitriol
HEPTASAL
Iron monosulfate
Iron sulfate (1:1)
Iron sulfate (FeSO4)
Iron sulphate
Iron sulphate heptahydrate
Iron vitriol
Iron(2+) sulfate
iron(2+) sulfate
Iron(2+) sulfate (1:1)
Iron(II) sulfate
Irospan
Kesuka
KROnoCHROME
Microfer Spansule
Mistrale 50
MONOSAL
Odophos
QUICKFLOC
Quickfloc
Quickfloc (salt)
SACHTOFER DD2C
SACHTOFER DRY
SACHTOFER MOIST
SACHTOFER S
SACHTOFER SEMIDRY
SACHTOFER TM
SFE 171
siarczan żelaza(II) jednowodny
siarczan żelaza(II) siedmiowodny
Slow-Fe
Solfato di ferro microcristallino eptaidrato
Sulferrous
Sulfuric acid, iron(2+) salt (1:1) (8CI, 9CI) (CA INDEX NAME)
Sulphate of iron

Other names:
Iron(II) sulphate
Ferrous sulfate
Green vitriol
Iron vitriol
Ferrous vitriol
Copperas
Melanterite
Szomolnokite

Other identifiers:
026-003-00-7
026-003-01-4
13463-43-9
139939-63-2
139939-63-2
56172-58-8
56172-58-8
7720-78-7
Ferrous Sulfate Heptahydrate
Green Vitriol; Copperas; Melanterite; Ferrous sulfate heptahydrate; Sulfuric acid, iron(2+) salt, heptahydrate; Ferrosulfat (German); cas no: 7782-63-0